# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- VHS PF00790.14 EMR61256.1 - 1.9e-40 137.7 2.4 2.6e-39 134.0 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EMR61256.1 - 5.5e-16 58.2 4.1 9.3e-16 57.4 2.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EMR61256.1 - 2.5e-05 23.4 14.4 0.0048 16.3 0.5 3.4 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-DHHC PF01529.15 EMR61256.1 - 0.00066 19.1 1.6 0.0014 18.0 1.1 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase FYVE_2 PF02318.11 EMR61256.1 - 0.011 15.5 1.1 0.025 14.4 0.7 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Ribosomal_S30AE PF02482.14 EMR61256.1 - 0.08 13.3 0.3 0.25 11.7 0.2 1.9 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein vMSA PF00695.14 EMR61256.1 - 0.13 11.4 2.7 0.2 10.7 1.8 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus C1_1 PF00130.17 EMR61256.1 - 0.6 9.8 8.2 0.34 10.6 4.1 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Fer4_2 PF12797.2 EMR61256.1 - 2.3 8.2 4.7 8.5 6.5 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain zf-C2H2_2 PF12756.2 EMR61257.1 - 2.8e-28 97.9 2.8 2.8e-28 97.9 1.9 2.9 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) Elf1 PF05129.8 EMR61257.1 - 0.22 11.2 2.0 31 4.3 0.1 3.3 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zf-C2H2 PF00096.21 EMR61257.1 - 0.63 10.4 8.7 11 6.6 0.2 4.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EMR61257.1 - 0.92 9.7 17.6 0.2 11.8 0.3 3.7 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding AMP-binding PF00501.23 EMR61258.1 - 1e-78 264.6 0.0 1.4e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme HECT PF00632.20 EMR61259.1 - 1.7e-66 224.5 0.0 2.5e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Sugar_tr PF00083.19 EMR61260.1 - 1.2e-32 113.1 37.0 2.4e-19 69.2 8.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR61260.1 - 2e-16 59.6 51.2 7.7e-13 47.8 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UCH PF00443.24 EMR61261.1 - 1.9e-23 82.9 0.0 2.8e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMR61261.1 - 7.7e-06 25.5 0.0 1.5e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EMR61261.1 - 0.0046 16.2 0.1 2.7 7.2 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase UCR_Fe-S_N PF10399.4 EMR61261.1 - 0.094 11.8 1.7 1.7 7.9 0.2 2.4 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal GTP_EFTU PF00009.22 EMR61262.1 - 1.4e-48 164.8 0.0 2.5e-48 164.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EMR61262.1 - 2.2e-23 82.1 0.6 5.5e-23 80.8 0.4 1.7 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 EMR61262.1 - 2.4e-09 37.1 0.1 2.3e-05 24.3 0.0 2.8 3 0 0 3 3 3 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EMR61262.1 - 3e-08 33.6 0.1 2.1e-07 30.9 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Miro PF08477.8 EMR61262.1 - 3.9e-06 27.3 0.9 0.0006 20.3 0.0 3.3 2 1 0 2 2 2 1 Miro-like protein GTP_EFTU_D3 PF03143.12 EMR61262.1 - 3.1e-05 24.0 0.1 0.00021 21.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain SRPRB PF09439.5 EMR61262.1 - 0.001 18.2 0.0 0.11 11.7 0.0 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.1 EMR61262.1 - 0.0018 17.8 0.0 0.0041 16.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Arf PF00025.16 EMR61262.1 - 0.0051 16.0 1.0 2.7 7.2 0.0 2.6 2 1 1 3 3 3 2 ADP-ribosylation factor family FeoB_N PF02421.13 EMR61262.1 - 0.01 15.1 0.1 0.22 10.8 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B Ras PF00071.17 EMR61262.1 - 0.023 14.0 0.2 0.37 10.1 0.0 2.3 1 1 1 2 2 2 0 Ras family Dynamin_N PF00350.18 EMR61262.1 - 0.03 14.1 0.3 3.5 7.4 0.0 3.0 1 1 1 2 2 2 0 Dynamin family Septin PF00735.13 EMR61262.1 - 0.051 12.5 0.0 0.098 11.6 0.0 1.4 1 0 0 1 1 1 0 Septin HSP70 PF00012.15 EMR61263.1 - 4.5e-269 893.4 14.6 5.1e-269 893.2 10.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMR61263.1 - 4.3e-19 68.2 1.9 1.6e-17 63.1 0.3 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 EMR61263.1 - 0.0056 15.5 0.7 0.12 11.2 0.2 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EMR61263.1 - 0.025 13.6 0.4 0.025 13.6 0.3 3.2 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EMR61263.1 - 0.14 11.7 0.0 0.83 9.2 0.0 2.3 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EMR61263.1 - 1 9.2 8.6 4.4 7.1 0.1 3.9 3 1 0 3 3 3 0 Cell division protein FtsA Cu-oxidase_3 PF07732.10 EMR61264.1 - 1.9e-38 130.8 2.6 1.9e-38 130.8 1.8 2.5 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMR61264.1 - 1.3e-37 128.4 10.2 5.1e-37 126.4 0.3 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EMR61264.1 - 9.9e-33 113.2 1.2 1.7e-32 112.5 0.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase Dsl1_C PF11989.3 EMR61265.1 - 0.02 14.0 0.4 0.025 13.7 0.2 1.1 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal Muted PF14942.1 EMR61265.1 - 0.049 13.4 0.6 0.071 12.9 0.4 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein YPEB PF14620.1 EMR61265.1 - 0.091 11.7 0.3 0.12 11.4 0.2 1.1 1 0 0 1 1 1 0 YpeB sporulation CBM_X2 PF03442.9 EMR61266.1 - 0.011 15.5 0.0 4.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain X2 Microtub_assoc PF07989.6 EMR61267.1 - 3.5e-19 68.4 7.8 3.5e-19 68.4 5.4 6.7 6 3 1 7 7 7 1 Microtubule associated Mto2_bdg PF12808.2 EMR61267.1 - 4e-08 33.2 11.3 4e-08 33.2 7.8 9.3 11 0 0 11 11 11 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 EMR61267.1 - 0.86 8.7 32.7 0.0061 15.7 1.4 6.0 5 2 1 7 7 7 0 Reovirus sigma C capsid protein adh_short PF00106.20 EMR61268.1 - 8.6e-14 51.7 0.1 1.2e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR61268.1 - 3.8e-06 26.6 0.1 5.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 KR domain EthD PF07110.6 EMR61269.1 - 4e-19 69.3 1.8 4.8e-19 69.0 1.3 1.1 1 0 0 1 1 1 1 EthD domain zf-C2H2 PF00096.21 EMR61271.1 - 0.017 15.4 4.9 0.67 10.4 0.0 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR61271.1 - 0.18 12.1 9.9 1.9 9.0 0.8 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Terminase_GpA PF05876.7 EMR61272.1 - 0.079 11.3 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) IucA_IucC PF04183.7 EMR61273.1 - 9e-07 28.3 0.0 1.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 IucA / IucC family DUF726 PF05277.7 EMR61274.1 - 2.4e-126 421.2 1.6 3.4e-126 420.8 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 EMR61274.1 - 0.069 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) p450 PF00067.17 EMR61275.1 - 6e-42 143.7 0.0 8.2e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PH PF00169.24 EMR61276.1 - 3e-07 30.5 0.1 1.5e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EMR61276.1 - 0.0005 20.2 0.0 0.0013 18.8 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain Peptidase_S9_N PF02897.10 EMR61276.1 - 0.15 10.6 0.1 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain H_lectin PF09458.5 EMR61277.1 - 5e-06 26.0 0.1 1e-05 25.0 0.1 1.5 2 0 0 2 2 2 1 H-type lectin domain SpoIIE PF07228.7 EMR61278.1 - 2.9e-06 27.1 0.1 8.4e-06 25.6 0.1 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EMR61278.1 - 0.00026 20.4 0.0 0.00033 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EMR61278.1 - 0.00078 18.9 0.0 0.11 11.8 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C TBPIP_N PF15517.1 EMR61279.1 - 3.7 7.2 6.2 0.3 10.7 0.6 1.9 2 0 0 2 2 2 0 TBP-interacting protein N-terminus PCI PF01399.22 EMR61280.1 - 2.5e-12 47.0 0.0 6.5e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain Lipase_GDSL_2 PF13472.1 EMR61281.1 - 1.5e-15 57.8 0.0 2.4e-15 57.1 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMR61281.1 - 1.1e-07 31.9 0.0 1.1e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase VPS9 PF02204.13 EMR61283.1 - 2.7e-30 104.4 0.0 4.6e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EMR61283.1 - 8.2e-09 34.7 0.1 7.6e-08 31.7 0.0 2.2 2 0 0 2 2 2 1 CUE domain Fcf1 PF04900.7 EMR61284.1 - 2.1e-24 85.5 0.1 4.6e-24 84.4 0.0 1.6 2 0 0 2 2 2 1 Fcf1 YL1 PF05764.8 EMR61284.1 - 0.1 12.1 11.5 0.17 11.4 8.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 EMR61284.1 - 0.27 9.2 2.9 0.44 8.5 2.0 1.3 1 0 0 1 1 1 0 CDC45-like protein TIMELESS_C PF05029.8 EMR61284.1 - 7.5 5.3 12.5 9.9 4.9 8.6 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region Radical_SAM PF04055.16 EMR61285.1 - 8.5e-17 61.8 1.7 1.1e-16 61.4 0.3 1.9 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.1 EMR61285.1 - 1.4e-07 31.7 0.7 5.4e-07 29.8 0.2 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EMR61285.1 - 8.4e-06 25.8 0.2 2.1e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Tat PF00539.13 EMR61285.1 - 0.21 11.2 4.5 0.36 10.4 0.3 2.8 3 0 0 3 3 3 0 Transactivating regulatory protein (Tat) MFS_1 PF07690.11 EMR61286.1 - 2.2e-38 131.9 28.7 2.2e-38 131.9 19.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR61286.1 - 1.5e-15 56.7 9.0 1.5e-15 56.7 6.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EMR61286.1 - 0.00058 18.0 1.1 0.0012 16.9 0.5 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_cc PF11790.3 EMR61287.1 - 5.5e-50 170.0 2.3 7.7e-50 169.5 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core HSP70 PF00012.15 EMR61288.1 - 9.6e-10 36.9 0.0 3.5e-09 35.1 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein Helicase_C PF00271.26 EMR61289.1 - 5.2e-11 42.2 0.3 8.2e-11 41.6 0.2 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain API5 PF05918.6 EMR61289.1 - 0.41 9.0 7.6 0.41 9.0 5.3 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2763 PF10961.3 EMR61289.1 - 3.5 8.0 9.5 2.7 8.4 5.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) DUF3628 PF12300.3 EMR61289.1 - 3.6 7.5 9.2 5 7.1 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Glyco_hydro_61 PF03443.9 EMR61290.1 - 2.9e-16 59.9 0.1 3.5e-16 59.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PepSY_2 PF13670.1 EMR61290.1 - 0.2 11.5 0.1 0.2 11.5 0.1 1.7 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain RabGAP-TBC PF00566.13 EMR61292.1 - 3.1e-35 121.5 0.1 4e-32 111.4 0.0 2.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain XRCC4 PF06632.7 EMR61293.1 - 1.8e-11 43.4 1.5 3.1e-11 42.7 1.1 1.4 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.3 EMR61293.1 - 0.00016 21.5 4.0 0.00027 20.8 2.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) DUF2514 PF10721.4 EMR61293.1 - 5.9 6.5 13.9 0.059 13.0 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) PepSY_2 PF13670.1 EMR61299.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Oxidored_FMN PF00724.15 EMR61300.1 - 4e-78 262.7 0.0 6.5e-78 262.1 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.6 EMR61300.1 - 0.24 10.9 0.0 0.4 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) polyprenyl_synt PF00348.12 EMR61301.1 - 8.3e-53 178.8 0.0 4.7e-49 166.5 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EMR61301.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Ras PF00071.17 EMR61303.1 - 2.3e-40 137.6 0.0 6.8e-38 129.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EMR61303.1 - 4.3e-18 65.9 0.0 6.1e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMR61303.1 - 5e-10 38.9 0.0 7.7e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMR61303.1 - 0.0031 17.4 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMR61303.1 - 0.014 14.5 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EMR61303.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EMR61303.1 - 0.067 12.6 0.0 7.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EMR61303.1 - 0.092 12.8 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EMR61303.1 - 0.097 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMR61303.1 - 0.12 12.3 1.1 2 8.3 0.1 2.6 3 0 0 3 3 3 0 AAA domain DUF2411 PF10304.4 EMR61303.1 - 0.2 11.2 0.2 0.4 10.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) Metallophos PF00149.23 EMR61305.1 - 7.5e-21 74.4 0.2 5.7e-14 51.9 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Macoilin PF09726.4 EMR61306.1 - 0.11 10.7 12.7 0.14 10.4 8.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4613 PF15390.1 EMR61306.1 - 0.63 8.1 6.9 0.81 7.7 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF1319 PF07028.6 EMR61306.1 - 1 9.5 11.5 2.1 8.5 8.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) IncA PF04156.9 EMR61306.1 - 7.3 6.1 21.8 1.4 8.5 9.4 2.2 1 1 1 2 2 2 0 IncA protein adh_short PF00106.20 EMR61308.1 - 0.072 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DUF427 PF04248.7 EMR61309.1 - 8.7e-30 102.2 3.6 9.7e-30 102.0 2.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Vma12 PF11712.3 EMR61310.1 - 4.7e-36 123.6 0.0 7.2e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase SCIMP PF15050.1 EMR61310.1 - 0.032 14.1 0.7 1.1 9.1 0.1 2.7 2 1 1 3 3 3 0 SCIMP protein DUF4149 PF13664.1 EMR61310.1 - 0.038 14.0 0.1 0.074 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Chordopox_A13L PF05961.6 EMR61310.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein FMN_dh PF01070.13 EMR61311.1 - 2.6e-124 414.6 0.3 3.5e-124 414.2 0.2 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EMR61311.1 - 9.6e-23 79.7 0.0 1.9e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EMR61311.1 - 5e-07 28.9 0.0 8.6e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EMR61311.1 - 0.00022 20.4 0.3 0.00037 19.7 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EMR61311.1 - 0.0015 17.5 0.2 0.0026 16.6 0.2 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EMR61311.1 - 0.031 13.5 0.7 1.7 7.8 0.1 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein DUF1793 PF08760.6 EMR61312.1 - 2.6e-41 141.3 0.6 4.1e-39 134.1 0.4 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 EMR61312.1 - 7.1e-05 22.1 0.1 0.00014 21.0 0.1 1.5 1 0 0 1 1 1 1 beta-Glucocerebrosidase 2 N terminal DUF1446 PF07287.6 EMR61314.1 - 4.4e-112 374.1 0.0 8.8e-112 373.1 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1446) Bystin PF05291.6 EMR61316.1 - 1.4e-125 418.1 0.0 1.9e-125 417.7 0.0 1.1 1 0 0 1 1 1 1 Bystin Sugar_tr PF00083.19 EMR61319.1 - 2.7e-45 154.7 15.3 3.4e-45 154.4 10.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR61319.1 - 1.1e-20 73.7 22.7 1.6e-20 73.1 15.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF383 PF04063.9 EMR61320.1 - 2.6e-63 213.0 0.0 8.1e-63 211.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EMR61320.1 - 1.8e-24 85.0 1.2 3.3e-24 84.1 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Fungal_trans PF04082.13 EMR61322.1 - 5.5e-06 25.4 0.4 1.1e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain NmrA PF05368.8 EMR61323.1 - 2.8e-40 138.0 0.0 3.3e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR61323.1 - 1e-23 84.2 0.3 1.5e-23 83.7 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR61323.1 - 2.2e-09 37.0 0.0 3.8e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR61323.1 - 8e-07 28.0 0.0 1.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EMR61323.1 - 0.0026 18.1 0.1 0.0058 17.0 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EMR61323.1 - 0.0037 17.1 0.1 0.0052 16.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 EMR61323.1 - 0.0069 16.3 1.4 0.016 15.1 1.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 EMR61323.1 - 0.0083 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.7 EMR61323.1 - 0.062 12.2 0.3 0.57 9.0 0.0 2.1 1 1 1 2 2 2 0 Male sterility protein Glyco_trans_4_4 PF13579.1 EMR61323.1 - 0.11 12.6 1.6 0.16 12.1 1.1 1.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain zf-C2H2_3 PF13878.1 EMR61324.1 - 1.1e-08 34.4 0.3 1.9e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO BCAS3 PF12490.3 EMR61325.1 - 0.024 13.9 0.1 0.035 13.4 0.1 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 RTA1 PF04479.8 EMR61326.1 - 5.5e-38 130.6 1.4 7.4e-38 130.2 1.0 1.1 1 0 0 1 1 1 1 RTA1 like protein PALP PF00291.20 EMR61327.1 - 2.4e-34 118.9 0.2 3e-34 118.6 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 EMR61327.1 - 0.0074 15.2 0.1 0.016 14.1 0.0 1.5 2 0 0 2 2 2 1 LytB protein NAD_binding_11 PF14833.1 EMR61328.1 - 1.6e-31 108.9 0.0 1.8e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Anp1 PF03452.9 EMR61330.1 - 4.1e-26 91.7 0.4 6.6e-26 91.0 0.3 1.4 1 1 0 1 1 1 1 Anp1 NTP_transf_3 PF12804.2 EMR61330.1 - 0.013 15.6 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF3477 PF11963.3 EMR61330.1 - 0.17 10.8 0.5 0.25 10.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3477) 2_5_RNA_ligase2 PF13563.1 EMR61331.1 - 0.11 12.1 0.0 2.9 7.5 0.0 2.1 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily Acyl-CoA_dh_1 PF00441.19 EMR61332.1 - 4.6e-32 111.2 0.7 8.6e-32 110.3 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMR61332.1 - 1.6e-30 105.9 0.3 3.2e-30 105.0 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EMR61332.1 - 1.3e-20 72.6 1.1 3e-20 71.4 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMR61332.1 - 3.4e-11 43.5 0.6 3.4e-11 43.5 0.4 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EMR61332.1 - 0.0086 15.4 0.2 0.058 12.7 0.1 2.1 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal TilS PF09179.6 EMR61332.1 - 0.06 13.3 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 TilS substrate binding domain Carboxyl_trans PF01039.17 EMR61335.1 - 3.8e-139 464.2 0.0 4.9e-139 463.8 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EMR61335.1 - 0.0027 16.9 1.4 0.6 9.2 0.0 2.6 3 0 0 3 3 3 2 Malonate decarboxylase gamma subunit (MdcE) adh_short_C2 PF13561.1 EMR61336.1 - 3e-26 92.6 0.0 3.8e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR61336.1 - 5.4e-20 71.9 0.1 7.6e-20 71.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR61336.1 - 9.5e-12 44.9 0.1 1.4e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR61336.1 - 0.00021 20.8 0.1 0.00057 19.3 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pectinesterase PF01095.14 EMR61338.1 - 9.8e-51 172.0 1.9 1.3e-50 171.6 1.3 1.1 1 0 0 1 1 1 1 Pectinesterase FSH1 PF03959.8 EMR61339.1 - 3.4e-26 91.9 0.0 5e-26 91.4 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) p450 PF00067.17 EMR61340.1 - 2.1e-55 188.0 0.0 2.6e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 EMR61341.1 - 8.2e-19 67.3 0.0 1.4e-18 66.6 0.0 1.3 1 1 0 1 1 1 1 Transferase family Glycos_transf_2 PF00535.21 EMR61341.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Esterase_phd PF10503.4 EMR61342.1 - 1e-06 28.2 0.0 1.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 EMR61342.1 - 0.058 13.2 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Mito_fiss_reg PF05308.6 EMR61343.1 - 1.1 8.6 10.2 1.6 8.0 7.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator KR PF08659.5 EMR61344.1 - 3.2e-65 219.2 1.9 7.9e-65 217.8 1.3 1.8 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR61344.1 - 2.2e-52 177.3 0.6 2.2e-52 177.3 0.4 3.3 4 0 0 4 4 4 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 EMR61344.1 - 3.7e-48 164.5 0.4 8.4e-48 163.3 0.3 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EMR61344.1 - 3e-44 151.3 0.0 4.7e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EMR61344.1 - 5.7e-42 142.3 0.1 1.8e-41 140.6 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EMR61344.1 - 2.6e-29 102.4 0.0 6.3e-29 101.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ADH_zinc_N PF00107.21 EMR61344.1 - 1e-19 70.3 0.7 7.9e-19 67.4 0.2 3.0 4 0 0 4 4 4 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR61344.1 - 3.1e-10 41.0 0.1 3.8e-09 37.5 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR61344.1 - 9.3e-09 35.0 0.3 2.8e-08 33.4 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 EMR61344.1 - 6.1e-07 29.1 0.1 1.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMR61344.1 - 9.2e-06 25.8 0.1 2.4e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 EMR61344.1 - 1.4e-05 24.1 0.0 3.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EMR61344.1 - 0.0087 15.3 0.0 0.021 14.0 0.0 1.7 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.12 EMR61344.1 - 0.016 15.6 0.0 0.089 13.2 0.0 2.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EMR61344.1 - 0.016 15.1 0.5 0.016 15.1 0.4 3.4 3 1 0 3 3 3 0 NADH(P)-binding Shikimate_DH PF01488.15 EMR61344.1 - 0.065 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_23 PF13489.1 EMR61345.1 - 7.2e-11 42.0 0.0 1.1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR61345.1 - 7.6e-09 35.3 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR61345.1 - 4e-07 30.4 0.0 7.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR61345.1 - 4.6e-07 30.4 0.0 8.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR61345.1 - 1.4e-06 27.6 0.0 2.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMR61345.1 - 2.6e-06 27.8 0.0 4.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR61345.1 - 0.00022 21.5 0.0 0.00039 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR61345.1 - 0.0011 18.9 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EMR61345.1 - 0.022 14.0 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain p450 PF00067.17 EMR61346.1 - 4.7e-44 150.6 0.0 5.3e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MinE PF03776.9 EMR61346.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE Caps_synth PF05704.7 EMR61347.1 - 5e-11 42.2 0.0 8.3e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EMR61347.1 - 0.00043 20.6 0.0 0.0008 19.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Methyltransf_11 PF08241.7 EMR61348.1 - 3.3e-07 30.6 0.0 5.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR61348.1 - 1.2e-06 28.8 0.0 1.9e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR61348.1 - 0.00021 20.8 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR61348.1 - 0.0064 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR61348.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 EMR61348.1 - 0.031 13.9 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Sigma70_ner PF04546.8 EMR61349.1 - 0.00092 18.8 2.9 0.0012 18.5 2.0 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region CDC45 PF02724.9 EMR61349.1 - 0.1 10.5 1.5 0.13 10.3 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 EMR61349.1 - 0.11 12.0 2.0 0.14 11.6 1.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF2201_N PF13203.1 EMR61349.1 - 0.12 11.5 0.3 0.16 11.1 0.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Nop14 PF04147.7 EMR61349.1 - 0.14 10.0 3.8 0.16 9.8 2.6 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 EMR61349.1 - 2.2 6.9 10.4 2.8 6.5 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 EMR61349.1 - 3.6 6.6 9.1 5.1 6.1 6.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 EMR61349.1 - 5.4 5.3 6.4 6.6 5.0 4.5 1.1 1 0 0 1 1 1 0 Daxx Family Sterol-sensing PF12349.3 EMR61350.1 - 1.3e-34 118.9 8.7 2.3e-34 118.0 6.0 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EMR61350.1 - 4e-09 34.9 1.7 5.5e-09 34.5 1.2 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.27 EMR61350.1 - 0.11 12.3 0.7 0.6 10.0 0.1 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat MMPL PF03176.10 EMR61350.1 - 0.19 10.3 0.0 0.19 10.3 0.0 2.2 2 0 0 2 2 2 0 MMPL family Ribosomal_60s PF00428.14 EMR61351.1 - 0.0063 16.8 0.2 0.0093 16.3 0.1 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Epimerase PF01370.16 EMR61351.1 - 0.098 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family BAF1_ABF1 PF04684.8 EMR61352.1 - 3.8 6.2 14.4 0.7 8.6 3.4 2.8 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor GDA1_CD39 PF01150.12 EMR61353.1 - 5.3e-97 325.0 0.0 6.6e-97 324.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PUL PF08324.6 EMR61354.1 - 3.9e-29 101.2 0.0 8.6e-29 100.1 0.0 1.5 1 1 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 EMR61354.1 - 1.4e-14 53.6 0.0 4.1e-14 52.1 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 EMR61354.1 - 8.9e-05 22.6 0.1 0.0017 18.5 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 EMR61354.1 - 0.0021 17.5 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein DSBA PF01323.15 EMR61354.1 - 0.012 15.1 0.1 4.3 6.8 0.0 2.5 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 EMR61354.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain Redoxin PF08534.5 EMR61354.1 - 0.044 13.3 0.1 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Redoxin Arm PF00514.18 EMR61354.1 - 0.13 12.1 1.3 4.9 7.1 0.0 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RR_TM4-6 PF06459.7 EMR61355.1 - 0.97 9.2 4.8 1.5 8.6 3.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cupin_8 PF13621.1 EMR61356.1 - 4.5e-65 219.6 0.0 5.8e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EMR61356.1 - 5.2e-06 25.9 0.1 0.00098 18.4 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 EMR61356.1 - 0.028 14.6 0.0 0.26 11.5 0.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase Ribosomal_60s PF00428.14 EMR61356.1 - 0.3 11.4 2.7 0.73 10.2 1.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF72 PF01904.13 EMR61357.1 - 0.054 13.2 0.6 0.13 12.0 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF72 Melibiase PF02065.13 EMR61358.1 - 5e-06 25.4 0.0 7.7e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_97 PF10566.4 EMR61358.1 - 0.012 14.6 0.0 0.049 12.7 0.0 1.8 1 1 0 1 1 1 0 Glycoside hydrolase 97 Aminotran_1_2 PF00155.16 EMR61359.1 - 2.7e-33 115.4 0.0 3.5e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II AMP-binding PF00501.23 EMR61360.1 - 1.5e-88 296.9 0.1 2.1e-88 296.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMR61360.1 - 1.2e-21 77.4 0.7 1.3e-19 70.9 0.4 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1967 PF09269.6 EMR61360.1 - 0.1 12.2 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Glyco_hydro_72 PF03198.9 EMR61361.1 - 1.8e-101 339.2 0.0 3.9e-101 338.1 0.0 1.5 3 0 0 3 3 3 1 Glucanosyltransferase Cellulase PF00150.13 EMR61361.1 - 0.003 16.8 0.4 0.018 14.2 0.3 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EMR61361.1 - 0.033 13.0 0.0 0.041 12.7 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_6 PF01341.12 EMR61362.1 - 2.6e-78 263.4 0.0 3.2e-78 263.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 DUF500 PF04366.7 EMR61364.1 - 3.2e-38 130.0 0.0 5.8e-38 129.1 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) HET PF06985.6 EMR61365.1 - 2.3e-16 60.2 2.1 1.3e-15 57.7 0.6 2.7 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) KR PF08659.5 EMR61366.1 - 7.9e-30 103.8 0.0 2.9e-29 102.0 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EMR61366.1 - 6.9e-26 91.1 0.0 2.3e-25 89.4 0.0 1.9 2 0 0 2 2 1 1 short chain dehydrogenase Methyltransf_12 PF08242.7 EMR61366.1 - 1.1e-17 64.3 0.0 8.9e-17 61.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR61366.1 - 9.6e-16 57.9 0.0 8.3e-14 51.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR61366.1 - 8.1e-12 45.4 0.0 1.9e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR61366.1 - 5.9e-11 42.9 0.0 1.8e-09 38.1 0.0 3.2 4 0 0 4 4 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR61366.1 - 3.8e-10 39.5 0.0 4e-09 36.2 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR61366.1 - 1e-06 29.0 0.0 2.6e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR61366.1 - 1.5e-06 28.3 0.1 5.5e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 EMR61366.1 - 1.6e-05 24.1 0.0 3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EMR61366.1 - 0.0012 18.2 0.0 0.0058 16.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EMR61366.1 - 0.014 15.4 0.0 0.059 13.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 EMR61366.1 - 0.051 12.6 0.0 0.94 8.4 0.0 2.2 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EMR61366.1 - 0.083 12.4 0.0 0.85 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 EMR61366.1 - 0.092 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Pkinase PF00069.20 EMR61367.1 - 2.9e-56 190.5 0.0 9.8e-56 188.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR61367.1 - 3.1e-27 95.2 0.0 6.7e-19 67.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMR61367.1 - 0.00034 19.6 0.0 0.33 9.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EMR61367.1 - 0.015 14.3 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.17 EMR61368.1 - 6.6e-15 54.4 0.0 1.1e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR61368.1 - 2e-11 43.7 0.0 3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EMR61368.1 - 7.1e-05 23.1 1.7 7.1e-05 23.1 1.2 3.4 2 1 2 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EMR61368.1 - 7.5e-05 22.5 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EMR61369.1 - 3.5e-07 29.7 7.3 9e-07 28.4 0.6 2.8 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MFS_1 PF07690.11 EMR61370.1 - 2.3e-18 66.0 40.3 3.1e-18 65.6 15.1 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.3 EMR61370.1 - 1.9e-05 23.3 14.1 1.9e-05 23.3 9.8 2.1 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like PTR2 PF00854.16 EMR61370.1 - 0.042 12.6 11.1 0.024 13.4 3.5 2.4 2 0 0 2 2 2 0 POT family DUF1426 PF07234.6 EMR61370.1 - 0.083 12.6 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1426) Sugar_tr PF00083.19 EMR61370.1 - 0.63 8.5 23.4 0.0058 15.2 7.4 2.4 2 1 0 2 2 2 0 Sugar (and other) transporter Acetyltransf_3 PF13302.1 EMR61372.1 - 4.3e-15 56.1 0.0 1.2e-14 54.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR61372.1 - 5.3e-15 55.2 0.1 8.6e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EMR61372.1 - 4e-09 36.5 0.0 6.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMR61372.1 - 5.6e-06 26.3 0.0 8.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR61372.1 - 2e-05 24.6 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR61372.1 - 0.015 15.4 0.1 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR61372.1 - 0.062 13.0 0.1 0.16 11.7 0.0 1.8 1 1 0 1 1 1 0 FR47-like protein zf-C2H2_4 PF13894.1 EMR61373.1 - 0.0066 16.6 0.5 2.4 8.6 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger Rep_fac_C PF08542.6 EMR61376.1 - 2.1e-24 85.3 0.1 6.9e-24 83.6 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EMR61376.1 - 1.7e-11 44.0 0.0 3.5e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 EMR61376.1 - 3.6e-07 30.3 0.7 8.5e-05 22.7 0.2 3.4 1 1 2 3 3 3 1 AAA domain AAA PF00004.24 EMR61376.1 - 1.1e-06 28.8 0.1 2.8e-06 27.5 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMR61376.1 - 0.00027 20.9 1.9 0.029 14.3 0.8 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EMR61376.1 - 0.0012 18.7 0.1 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EMR61376.1 - 0.0051 16.8 0.3 0.23 11.5 0.2 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.22 EMR61376.1 - 0.018 15.3 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EMR61376.1 - 0.021 14.5 0.1 0.07 12.8 0.1 1.9 1 1 0 1 1 1 0 Archaeal ATPase Aconitase_B_N PF11791.3 EMR61376.1 - 0.038 13.8 0.1 2.4 7.9 0.0 2.8 3 0 0 3 3 3 0 Aconitate B N-terminal domain T4SS-DNA_transf PF02534.9 EMR61376.1 - 0.046 12.3 0.1 0.15 10.5 0.0 1.7 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer AAA_10 PF12846.2 EMR61376.1 - 0.051 13.0 0.2 2.1 7.7 0.0 2.5 1 1 0 2 2 2 0 AAA-like domain Rad17 PF03215.10 EMR61376.1 - 0.055 12.1 0.0 0.076 11.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SNF2_N PF00176.18 EMR61376.1 - 0.077 11.7 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF2861 PF11060.3 EMR61376.1 - 0.082 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) AAA_29 PF13555.1 EMR61376.1 - 0.12 11.9 0.1 0.87 9.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EMR61376.1 - 0.19 11.4 0.8 1.4 8.6 0.6 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EMR61376.1 - 0.39 10.2 1.9 1.8 8.1 1.3 2.0 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EMR61377.1 - 1.4e-28 99.6 40.8 8.5e-28 97.0 28.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR61377.1 - 3.8e-19 68.3 15.7 4.8e-19 67.9 10.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cation_ATPase_C PF00689.16 EMR61377.1 - 0.47 9.9 19.2 0.048 13.1 1.4 2.9 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus DUF2919 PF11143.3 EMR61377.1 - 0.6 9.9 4.8 1.9 8.3 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2919) adh_short PF00106.20 EMR61378.1 - 4.1e-17 62.6 0.7 7.8e-17 61.6 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR61378.1 - 3.4e-08 33.3 0.1 5.7e-08 32.6 0.1 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR61378.1 - 2.3e-07 30.8 0.0 2.9e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.13 EMR61378.1 - 0.051 13.5 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain p450 PF00067.17 EMR61379.1 - 9e-50 169.5 0.0 1.4e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GST_N_2 PF13409.1 EMR61380.1 - 9.7e-23 79.9 0.2 6.7e-22 77.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR61380.1 - 1.9e-15 56.5 0.0 5.3e-15 55.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMR61380.1 - 2e-06 27.6 0.0 5.8e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMR61380.1 - 9e-06 25.8 0.1 0.00069 19.7 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMR61380.1 - 0.00044 20.6 0.0 0.00079 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ThiF PF00899.16 EMR61381.1 - 1.5e-51 173.7 0.0 4.7e-31 107.4 0.0 2.7 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EMR61381.1 - 7e-39 132.8 0.1 2.3e-38 131.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EMR61381.1 - 4.1e-37 125.5 4.1 7e-27 92.8 0.2 2.6 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EMR61381.1 - 2e-24 84.6 1.0 5e-21 73.8 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site DDHD PF02862.12 EMR61382.1 - 6.9e-71 238.6 0.1 6.9e-71 238.6 0.0 3.2 2 1 0 2 2 2 1 DDHD domain DUF2305 PF10230.4 EMR61382.1 - 0.063 12.6 0.1 0.23 10.8 0.0 1.9 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2305) NPR3 PF03666.8 EMR61382.1 - 2.8 6.3 6.1 2 6.8 0.0 2.9 3 0 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 UCH PF00443.24 EMR61383.1 - 5.7e-42 143.6 0.0 1.1e-41 142.7 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMR61383.1 - 6e-17 62.0 0.0 1.5e-16 60.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MFS_1 PF07690.11 EMR61384.1 - 1.2e-32 112.9 31.1 1.2e-32 112.9 21.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily zf-CCHC PF00098.18 EMR61386.1 - 2.3e-45 150.4 59.8 2e-08 33.7 3.0 7.4 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EMR61386.1 - 5.1e-08 32.4 43.8 0.033 13.8 0.3 6.8 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EMR61386.1 - 0.00026 20.6 45.5 0.1 12.3 0.4 6.6 4 2 3 7 7 7 5 Zinc knuckle zf-CCHC_2 PF13696.1 EMR61386.1 - 0.019 14.4 7.0 0.062 12.8 0.7 6.2 3 2 3 6 6 6 0 Zinc knuckle RMF PF04957.7 EMR61386.1 - 6.4 6.5 16.0 0.24 11.1 0.5 3.7 3 1 1 4 4 4 0 Ribosome modulation factor SAE2 PF08573.5 EMR61387.1 - 4.9e-22 78.4 3.3 1.7e-21 76.7 0.0 2.8 2 1 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus ATG16 PF08614.6 EMR61387.1 - 0.048 13.4 9.0 0.12 12.1 6.2 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EMR61387.1 - 0.15 11.2 2.2 0.23 10.6 0.4 1.9 2 1 0 2 2 2 0 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 EMR61387.1 - 0.58 10.3 6.1 0.11 12.6 1.0 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 EMR61387.1 - 2.7 8.3 11.5 0.66 10.3 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EMR61387.1 - 7.7 6.8 13.1 18 5.7 3.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) MFS_1 PF07690.11 EMR61388.1 - 1.5e-31 109.4 58.3 1.5e-31 109.4 40.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily RskA PF10099.4 EMR61388.1 - 0.014 15.1 2.4 0.17 11.6 0.1 2.5 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Fungal_trans PF04082.13 EMR61389.1 - 0.0058 15.5 4.9 0.0041 16.0 1.7 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain RNA_pol_Rpb1_5 PF04998.12 EMR61390.1 - 1.3e-81 273.9 0.1 2.5e-81 272.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EMR61390.1 - 9.2e-66 222.3 0.0 2.6e-56 191.3 0.0 2.3 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EMR61390.1 - 5.5e-64 215.1 0.0 1.6e-63 213.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EMR61390.1 - 3.8e-39 133.9 0.0 7.5e-39 132.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EMR61390.1 - 4.6e-28 97.1 1.1 8.3e-28 96.2 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DWNN PF08783.6 EMR61390.1 - 0.088 12.7 0.3 0.27 11.1 0.2 1.8 1 0 0 1 1 1 0 DWNN domain SAP PF02037.22 EMR61391.1 - 0.0031 16.9 3.3 0.0033 16.8 1.1 1.9 2 0 0 2 2 2 1 SAP domain Telomere_Sde2_2 PF13297.1 EMR61391.1 - 0.0042 16.3 0.2 0.0082 15.3 0.2 1.5 1 0 0 1 1 1 1 Telomere stability C-terminal DUF2201_N PF13203.1 EMR61391.1 - 1.9 7.5 14.6 0.22 10.6 0.4 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain Surp PF01805.15 EMR61392.1 - 6.2e-18 64.1 0.0 1.4e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Surp module TAF4 PF05236.9 EMR61392.1 - 4.6 6.4 6.9 0.26 10.5 0.9 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family MFS_1 PF07690.11 EMR61393.1 - 2.1e-42 145.1 29.4 5.1e-33 114.2 8.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR61393.1 - 2.2e-07 29.8 7.6 0.00011 20.9 5.3 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter Folate_carrier PF01770.13 EMR61393.1 - 0.00028 19.5 0.8 0.00033 19.2 0.0 1.5 2 0 0 2 2 2 1 Reduced folate carrier MFS_3 PF05977.8 EMR61393.1 - 0.0018 16.5 14.3 0.068 11.2 2.2 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.2 EMR61393.1 - 0.0034 17.1 3.2 0.079 12.7 0.1 3.1 3 0 0 3 3 3 1 MFS_1 like family DUF791 PF05631.9 EMR61393.1 - 0.031 12.9 1.3 0.064 11.9 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF791) OATP PF03137.15 EMR61393.1 - 0.048 11.7 2.8 0.2 9.6 0.2 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Zip PF02535.17 EMR61393.1 - 0.12 11.2 1.8 0.24 10.3 1.3 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter SCIMP PF15050.1 EMR61393.1 - 0.35 10.7 1.1 27 4.6 0.1 3.0 3 0 0 3 3 3 0 SCIMP protein NOA36 PF06524.7 EMR61393.1 - 6 6.0 5.1 11 5.1 3.6 1.4 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.5 EMR61393.1 - 7.2 5.5 9.3 13 4.7 6.4 1.3 1 0 0 1 1 1 0 BUD22 MFS_1 PF07690.11 EMR61394.1 - 3.7e-27 94.9 32.4 4.4e-26 91.4 18.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR61394.1 - 1.1e-14 53.8 3.8 1.1e-14 53.8 2.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMR61394.1 - 3.3e-07 28.8 1.7 4.9e-07 28.3 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 EMR61394.1 - 0.0017 17.1 1.5 0.0059 15.3 0.0 2.3 2 1 0 2 2 2 1 BT1 family DUF4381 PF14316.1 EMR61394.1 - 0.22 11.6 4.2 1.3 9.1 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) ATG22 PF11700.3 EMR61394.1 - 3 6.1 16.4 0.0058 15.1 1.6 2.9 2 2 1 3 3 3 0 Vacuole effluxer Atg22 like DAO PF01266.19 EMR61395.1 - 6.8e-48 163.3 0.4 1e-47 162.8 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMR61395.1 - 7.5e-08 32.2 0.1 0.014 15.1 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EMR61395.1 - 2.2e-06 27.5 0.0 5.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EMR61395.1 - 0.00028 19.8 0.0 0.0014 17.6 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EMR61395.1 - 0.0047 16.8 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMR61395.1 - 0.0082 14.8 0.0 0.09 11.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EMR61395.1 - 0.033 13.1 0.0 3.9 6.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EMR61395.1 - 0.074 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 EMR61395.1 - 0.084 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase TBP PF00352.16 EMR61396.1 - 1.5e-68 226.1 0.1 4.5e-35 118.8 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EMR61396.1 - 0.00023 21.1 0.0 0.86 9.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 EMR61396.1 - 0.0021 18.4 0.3 0.003 17.8 0.2 1.4 1 0 0 1 1 1 1 Ribonuclease (pollen allergen) KH_1 PF00013.24 EMR61397.1 - 6.6e-71 233.8 26.1 3.2e-13 49.0 0.1 11.7 12 1 0 12 12 12 8 KH domain KH_3 PF13014.1 EMR61397.1 - 1.3e-45 152.2 20.6 1.9e-09 36.9 0.3 10.6 11 0 0 11 11 11 7 KH domain SLS PF14611.1 EMR61397.1 - 2.3e-09 36.9 5.0 0.0048 16.3 0.0 6.5 3 1 4 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 EMR61397.1 - 5e-08 32.3 13.6 0.1 12.2 0.1 6.2 5 1 1 6 6 6 3 KH domain BMC PF00936.14 EMR61397.1 - 0.0036 16.9 0.5 42 3.9 0.0 4.9 5 0 0 5 5 5 0 BMC domain Atx10homo_assoc PF09759.4 EMR61398.1 - 1.1e-08 34.6 0.3 2.9e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain CAP_N PF01213.14 EMR61398.1 - 0.0008 18.7 20.6 0.005 16.1 0.3 2.7 2 0 0 2 2 2 2 Adenylate cyclase associated (CAP) N terminal PPP4R2 PF09184.6 EMR61398.1 - 0.24 10.9 10.6 0.74 9.3 7.3 1.8 1 0 0 1 1 1 0 PPP4R2 Mito_fiss_reg PF05308.6 EMR61398.1 - 0.34 10.2 25.9 0.1 11.9 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator Zip PF02535.17 EMR61398.1 - 0.52 9.2 8.6 0.93 8.4 6.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter BTV_NS2 PF04514.7 EMR61398.1 - 2.9 6.6 9.7 4.8 5.9 6.7 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 NicO PF03824.11 EMR61398.1 - 4.5 6.5 6.5 7 5.8 4.5 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein ARID PF01388.16 EMR61399.1 - 1.5e-15 56.7 0.0 4.7e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Zip PF02535.17 EMR61399.1 - 7 5.5 8.8 11 4.9 6.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ECM11 PF15463.1 EMR61400.1 - 6.3e-39 133.4 3.4 6.3e-39 133.4 2.4 2.0 2 0 0 2 2 2 1 Extracellular mutant protein 11 Utp21 PF04192.7 EMR61401.1 - 7.2e-81 270.7 0.0 9.8e-81 270.3 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EMR61401.1 - 9.1e-25 85.5 21.6 1.8e-05 24.3 0.4 9.1 10 0 0 10 10 10 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EMR61401.1 - 1.9e-05 23.1 0.0 3.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 EMR61401.1 - 0.00026 20.5 0.1 0.13 11.6 0.0 2.8 2 1 0 2 2 2 2 PQQ-like domain Nup160 PF11715.3 EMR61401.1 - 0.0024 16.1 0.6 0.89 7.6 0.0 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 His_Phos_2 PF00328.17 EMR61402.1 - 6.9e-131 436.6 0.2 8.8e-131 436.3 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EMR61402.1 - 4.9e-07 29.4 0.0 9.7e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain MFS_1 PF07690.11 EMR61403.1 - 2.4e-35 121.9 50.4 5.7e-35 120.6 34.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR61403.1 - 0.086 11.3 31.5 0.004 15.7 10.6 2.8 3 0 0 3 3 3 0 Sugar (and other) transporter Cyto_heme_lyase PF01265.12 EMR61404.1 - 9.3e-57 192.5 0.0 1.2e-56 192.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase GHMP_kinases_N PF00288.21 EMR61405.1 - 1e-10 41.4 3.4 3e-10 40.0 1.3 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMR61405.1 - 0.1 12.8 0.0 0.31 11.2 0.0 1.9 1 0 0 1 1 1 0 GHMP kinases C terminal Endosulfine PF04667.12 EMR61406.1 - 3.7e-21 74.8 0.1 7e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region HET PF06985.6 EMR61407.1 - 3.4e-25 88.8 0.2 1e-24 87.2 0.1 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.8 EMR61407.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Ras PF00071.17 EMR61408.1 - 4.1e-18 65.3 0.0 5.7e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR61408.1 - 0.016 15.6 0.0 0.035 14.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Arf PF00025.16 EMR61408.1 - 0.032 13.4 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMR61408.1 - 0.052 12.9 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain TRP PF06011.7 EMR61409.1 - 3.5e-148 493.8 33.1 4.3e-148 493.5 23.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EMR61409.1 - 1.8e-31 109.0 0.2 3.2e-31 108.2 0.1 1.4 1 0 0 1 1 1 1 ML-like domain DUF3433 PF11915.3 EMR61410.1 - 1.8e-45 153.0 16.3 5.8e-26 90.4 0.7 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) ABC2_membrane_3 PF12698.2 EMR61410.1 - 0.38 9.7 5.4 0.49 9.3 0.0 3.1 3 1 0 3 3 3 0 ABC-2 family transporter protein AMP-binding PF00501.23 EMR61411.1 - 1.6e-30 105.8 0.0 2.2e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EMR61411.1 - 1.2e-28 99.7 0.0 2.5e-28 98.6 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EMR61411.1 - 1e-11 44.9 0.0 2e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EMR61411.1 - 2.1e-09 37.1 0.0 9.7e-09 34.9 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EMR61411.1 - 1.9e-07 31.9 0.3 1.2e-06 29.3 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 EMR61411.1 - 0.044 13.6 0.7 0.15 12.0 0.3 2.0 3 0 0 3 3 3 0 short chain dehydrogenase NmrA PF05368.8 EMR61411.1 - 0.069 12.3 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.14 EMR61411.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PS-DH PF14765.1 EMR61412.1 - 9.8e-32 110.2 0.0 1.8e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EMR61412.1 - 6.5e-23 81.3 0.0 2.1e-22 79.6 0.0 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR61412.1 - 1.7e-17 63.8 0.2 1.6e-16 60.6 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_12 PF08242.7 EMR61412.1 - 7.9e-11 42.3 0.0 1.7e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR61412.1 - 7.6e-06 26.3 0.0 1.8e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR61412.1 - 9.9e-05 22.6 0.0 0.00029 21.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR61412.1 - 0.00031 20.3 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR61412.1 - 0.0052 17.0 0.0 0.019 15.2 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EMR61412.1 - 0.007 16.1 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR61412.1 - 0.012 16.2 0.0 0.041 14.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain RNA_pol_Rpc4 PF05132.9 EMR61412.1 - 0.25 11.3 0.0 0.5 10.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Dioxygenase_C PF00775.16 EMR61413.1 - 1.8e-51 173.9 0.0 2.2e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase CarboxypepD_reg PF13620.1 EMR61413.1 - 5.2e-05 23.2 0.0 0.00012 22.0 0.0 1.6 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Dioxygenase_N PF04444.9 EMR61413.1 - 0.017 15.0 0.0 0.091 12.7 0.0 2.1 2 0 0 2 2 2 0 Catechol dioxygenase N terminus Big_1 PF02369.11 EMR61413.1 - 0.052 13.4 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Pkinase PF00069.20 EMR61415.1 - 4.2e-56 189.9 0.0 5.3e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR61415.1 - 1.8e-28 99.3 0.6 2.1e-27 95.8 0.4 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR61415.1 - 0.18 10.7 0.0 0.42 9.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 EMR61416.1 - 7.1e-10 38.4 0.0 2e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR61416.1 - 0.0038 16.3 0.0 0.0088 15.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase zf-LITAF-like PF10601.4 EMR61417.1 - 0.026 14.3 0.5 0.036 13.9 0.4 1.2 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain NmrA PF05368.8 EMR61418.1 - 7.2e-27 94.1 0.0 1.1e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR61418.1 - 6.5e-19 68.6 0.0 8.4e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMR61418.1 - 0.12 11.0 0.1 0.21 10.2 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMR61418.1 - 0.13 11.7 0.0 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Ima1_N PF09779.4 EMR61419.1 - 5e-33 114.3 0.7 9.3e-33 113.5 0.5 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.2 EMR61419.1 - 0.41 10.4 4.5 4.9 7.0 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 EMR61419.1 - 0.63 9.8 4.7 0.51 10.1 1.2 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain NACHT PF05729.7 EMR61420.1 - 2.3e-07 30.6 0.0 3.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMR61420.1 - 8e-06 25.9 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMR61420.1 - 0.00039 20.5 0.0 0.00068 19.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMR61420.1 - 0.0028 17.1 0.0 0.0033 16.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMR61420.1 - 0.003 17.2 0.0 0.0071 16.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain cobW PF02492.14 EMR61420.1 - 0.0085 15.5 0.1 0.013 14.9 0.0 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EMR61420.1 - 0.0099 14.7 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain FtsK_SpoIIIE PF01580.13 EMR61420.1 - 0.012 15.0 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 EMR61420.1 - 0.016 15.0 0.0 0.19 11.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMR61420.1 - 0.023 14.9 0.0 0.043 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMR61420.1 - 0.035 14.9 0.1 0.081 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EMR61420.1 - 0.038 14.1 0.1 0.059 13.5 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EMR61420.1 - 0.04 12.8 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.6 EMR61420.1 - 0.069 13.0 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Torsin ABC_tran PF00005.22 EMR61420.1 - 0.078 13.2 0.0 0.092 13.0 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EMR61420.1 - 0.15 11.9 0.0 0.19 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EMR61420.1 - 0.15 11.5 0.0 0.19 11.2 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Alg14 PF08660.6 EMR61421.1 - 7.9e-39 133.3 0.0 1.1e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Ank_2 PF12796.2 EMR61422.1 - 2.7e-39 133.3 0.0 3e-15 56.3 0.0 3.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMR61422.1 - 6.5e-32 107.7 2.9 8.7e-10 37.9 0.0 6.9 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 EMR61422.1 - 2.2e-23 79.9 0.2 5.5e-05 23.0 0.0 6.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.1 EMR61422.1 - 4.3e-22 78.0 1.8 1.9e-07 31.4 0.0 6.0 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR61422.1 - 5.7e-21 74.0 2.7 0.00025 21.1 0.0 6.6 3 3 5 8 8 8 4 Ankyrin repeats (many copies) DUF3447 PF11929.3 EMR61422.1 - 0.026 14.3 0.0 0.099 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) U3_snoRNA_assoc PF08297.6 EMR61423.1 - 6.9e-09 35.8 2.5 6.9e-09 35.8 1.7 3.3 3 1 0 3 3 3 1 U3 snoRNA associated Ribosomal_S22 PF08136.6 EMR61423.1 - 1.9 8.6 5.0 6.7 6.9 0.1 2.8 2 0 0 2 2 2 0 30S ribosomal protein subunit S22 family GCV_T PF01571.16 EMR61424.1 - 1.9e-19 69.8 0.0 2.7e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EMR61424.1 - 0.0034 17.3 0.0 0.029 14.4 0.0 2.5 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain PH_10 PF15411.1 EMR61425.1 - 6.3e-27 94.0 0.1 1e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EMR61425.1 - 1.3e-10 41.1 0.0 5.7e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EMR61425.1 - 9.7e-09 35.1 0.1 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain PH PF00169.24 EMR61425.1 - 0.075 13.2 0.1 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 PH domain DUF1147 PF06615.6 EMR61425.1 - 0.098 12.5 0.5 0.24 11.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) NAD_synthase PF02540.12 EMR61425.1 - 0.1 11.4 0.0 0.75 8.6 0.0 2.0 2 0 0 2 2 2 0 NAD synthase Hat1_N PF10394.4 EMR61426.1 - 1.2e-37 129.4 0.0 1.9e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 EMR61426.1 - 0.041 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PTPLA PF04387.9 EMR61427.1 - 9.6e-50 168.2 7.3 1.5e-49 167.5 5.1 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Pkinase PF00069.20 EMR61428.1 - 1.6e-51 174.9 0.0 2e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR61428.1 - 6.8e-35 120.3 0.0 8.5e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR61428.1 - 6.6e-08 31.8 0.0 9.6e-08 31.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Amastin PF07344.6 EMR61429.1 - 0.055 13.0 2.3 0.071 12.7 0.6 1.7 1 1 1 2 2 2 0 Amastin surface glycoprotein DIOX_N PF14226.1 EMR61430.1 - 4.5e-21 75.5 0.0 7.2e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMR61430.1 - 3.3e-17 62.5 0.0 5.5e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2457 PF10446.4 EMR61431.1 - 0.012 14.3 8.1 0.013 14.2 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EMR61431.1 - 0.27 9.2 10.1 0.33 8.9 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L37ae PF01780.14 EMR61432.1 - 2.3e-36 123.5 9.0 2.5e-36 123.3 6.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family DUF1364 PF07102.7 EMR61432.1 - 0.0033 17.2 0.6 0.0045 16.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) Abhydrolase_6 PF12697.2 EMR61433.1 - 4.2e-07 30.0 1.0 5.3e-07 29.7 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR61433.1 - 2.2e-06 27.4 8.8 4.5e-05 23.2 6.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EMR61433.1 - 2.6e-05 23.6 0.0 4.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EMR61433.1 - 4.5e-05 23.1 0.0 9.1e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EMR61433.1 - 0.0063 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 EMR61433.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 EMR61433.1 - 0.017 14.7 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EMR61433.1 - 0.024 14.0 0.0 0.073 12.5 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF4366 PF14283.1 EMR61433.1 - 0.14 11.5 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Sel1 PF08238.7 EMR61434.1 - 0.0082 16.7 0.6 0.4 11.3 0.0 3.5 3 0 0 3 3 3 1 Sel1 repeat TPR_19 PF14559.1 EMR61434.1 - 0.012 15.9 0.2 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMR61434.1 - 0.02 14.8 0.2 0.31 11.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMR61434.1 - 0.043 13.4 0.3 0.84 9.3 0.0 2.4 1 1 1 2 2 2 0 TPR repeat Apc3 PF12895.2 EMR61434.1 - 0.05 13.7 0.1 0.13 12.4 0.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EMR61434.1 - 0.059 13.2 0.2 5.8 6.9 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMR61434.1 - 0.11 13.0 2.2 4.7 7.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMR61434.1 - 0.3 11.8 7.9 19 6.2 0.3 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMR61434.1 - 0.49 11.1 5.7 18 6.1 0.7 3.2 2 2 0 2 2 2 0 Tetratricopeptide repeat Saccharop_dh PF03435.13 EMR61435.1 - 1.5e-20 73.5 0.0 4.7e-18 65.3 0.0 2.0 2 0 0 2 2 2 2 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EMR61435.1 - 0.01 16.1 0.0 0.023 14.9 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMR61435.1 - 0.03 14.4 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amidohydro_2 PF04909.9 EMR61436.1 - 2.4e-38 132.2 1.8 3.5e-38 131.7 1.2 1.3 1 1 0 1 1 1 1 Amidohydrolase Asparaginase PF00710.15 EMR61436.1 - 0.041 12.7 0.0 0.08 11.8 0.0 1.4 1 0 0 1 1 1 0 Asparaginase GTP_EFTU PF00009.22 EMR61437.1 - 4e-53 179.6 0.0 7.3e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EMR61437.1 - 6.9e-16 57.9 0.0 1.9e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EMR61437.1 - 3e-09 36.5 0.0 7e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EMR61437.1 - 3.2e-08 33.5 0.0 8.9e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EMR61437.1 - 2e-06 27.3 0.1 0.008 15.7 0.0 3.1 3 1 0 3 3 3 2 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EMR61437.1 - 0.0047 16.8 0.0 0.0095 15.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ribosomal_L30_N PF08079.7 EMR61438.1 - 9.3e-23 80.0 18.4 1.6e-22 79.3 12.7 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EMR61438.1 - 7.8e-18 63.8 2.1 1.1e-17 63.2 0.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_S11 PF00411.14 EMR61439.1 - 2.5e-40 137.0 0.5 3e-40 136.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 EMR61439.1 - 0.074 11.9 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Cpn60_TCP1 PF00118.19 EMR61440.1 - 4.6e-135 450.9 6.4 5.2e-135 450.7 4.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Repressor_Mnt PF11423.3 EMR61440.1 - 0.41 9.9 2.3 1.3 8.3 0.0 2.9 3 0 0 3 3 3 0 Regulatory protein Mnt Fe-S_biosyn PF01521.15 EMR61441.1 - 1.4e-11 44.2 0.0 4.7e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis Clathrin-link PF09268.5 EMR61441.1 - 0.075 12.0 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Clathrin, heavy-chain linker DUF605 PF04652.11 EMR61441.1 - 0.23 10.8 13.3 0.23 10.8 9.2 1.1 1 0 0 1 1 1 0 Vta1 like Glyco_hydro_18 PF00704.23 EMR61442.1 - 1.4e-10 41.1 0.7 2.6e-10 40.2 0.5 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 WD40 PF00400.27 EMR61443.1 - 6e-51 168.5 21.4 4.1e-11 42.3 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EMR61443.1 - 9.2e-13 47.6 0.9 2.2e-12 46.4 0.6 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EMR61443.1 - 2.2e-10 39.3 12.2 0.0075 14.4 0.1 6.7 2 1 5 7 7 7 5 Nucleoporin Nup120/160 F-box PF00646.28 EMR61443.1 - 1.2e-06 27.9 2.3 2.7e-06 26.8 1.6 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EMR61443.1 - 0.0018 17.7 5.0 0.073 12.5 1.7 2.8 1 1 1 2 2 2 2 PQQ-like domain BBS2_Mid PF14783.1 EMR61443.1 - 0.0034 17.1 0.1 0.62 9.8 0.0 3.4 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EMR61443.1 - 0.0047 17.1 6.4 8.7 6.7 0.0 5.7 6 1 0 6 6 6 1 PQQ-like domain Nucleoporin_N PF08801.6 EMR61443.1 - 0.04 12.6 0.2 0.17 10.5 0.1 2.0 1 1 1 2 2 2 0 Nup133 N terminal like AMP-binding PF00501.23 EMR61444.1 - 3.6e-57 193.6 0.0 5.5e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.19 EMR61444.1 - 1.5e-11 43.2 2.0 0.0015 17.9 1.0 5.5 5 1 0 5 5 5 2 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.20 EMR61444.1 - 3.5e-11 43.2 0.0 9e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.1 EMR61444.1 - 0.0095 15.4 11.6 0.012 15.1 0.3 4.5 5 2 0 5 5 5 2 Hexapeptide repeat of succinyl-transferase GH3 PF03321.8 EMR61444.1 - 0.24 9.8 0.1 1.1 7.7 0.1 1.8 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Ribosomal_L12 PF00542.14 EMR61445.1 - 1.6e-20 72.8 3.0 2.4e-20 72.2 2.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 EMR61445.1 - 3.2 8.2 14.0 0.34 11.3 5.1 2.3 1 1 2 3 3 3 0 60s Acidic ribosomal protein Arylsulfotran_2 PF14269.1 EMR61446.1 - 4.4e-109 364.2 1.2 5.1e-109 364.0 0.9 1.0 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EMR61446.1 - 2.9e-11 42.5 0.3 6.2e-10 38.1 0.2 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Paf67 PF10255.4 EMR61447.1 - 1.8e-152 507.9 0.5 2.1e-152 507.6 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EMR61447.1 - 0.034 14.0 0.0 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HMG_box PF00505.14 EMR61449.1 - 1.7e-06 28.2 5.2 1.7e-06 28.2 3.6 2.7 2 1 1 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMR61449.1 - 7.8e-06 26.1 3.4 7.8e-06 26.1 2.3 2.1 2 1 0 2 2 2 1 HMG-box domain bZIP_1 PF00170.16 EMR61449.1 - 0.017 15.0 1.8 0.017 15.0 1.3 3.0 3 1 0 3 3 3 0 bZIP transcription factor DUF972 PF06156.8 EMR61449.1 - 0.28 11.5 0.2 0.28 11.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) KfrA_N PF11740.3 EMR61449.1 - 0.35 11.3 8.7 0.32 11.4 1.8 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DnaJ PF00226.26 EMR61450.1 - 3.7e-14 52.1 0.3 9.8e-14 50.8 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain SNF2_N PF00176.18 EMR61451.1 - 5.2e-68 229.0 0.0 7.6e-68 228.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMR61451.1 - 3.5e-15 55.6 0.0 8.2e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EMR61451.1 - 0.0001 21.2 0.0 0.00043 19.2 0.0 1.9 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EMR61452.1 - 5e-39 133.4 0.0 2.7e-38 131.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR61452.1 - 7.5e-27 93.0 0.0 2e-26 91.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMR61452.1 - 0.00011 21.1 0.0 0.00024 20.0 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 EMR61452.1 - 0.0038 17.0 0.0 0.014 15.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit XRCC4 PF06632.7 EMR61452.1 - 0.064 12.1 1.9 0.12 11.2 1.3 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 GP40 PF11025.3 EMR61452.1 - 0.39 10.2 3.4 0.67 9.5 2.3 1.3 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium BUD22 PF09073.5 EMR61453.1 - 9.6 5.1 16.9 18 4.2 11.7 1.4 1 0 0 1 1 1 0 BUD22 CTK3 PF12243.3 EMR61454.1 - 9e-54 180.8 1.2 1.2e-53 180.4 0.8 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EMR61454.1 - 7.3e-18 64.3 7.1 2e-17 62.9 4.9 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus BAR_3_WASP_bdg PF10456.4 EMR61454.1 - 0.006 15.8 4.2 0.64 9.2 1.5 2.1 2 0 0 2 2 2 2 WASP-binding domain of Sorting nexin protein DUF155 PF02582.9 EMR61455.1 - 1.6e-55 187.7 0.1 2e-55 187.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 P5CR_dimer PF14748.1 EMR61456.1 - 6.9e-16 58.1 1.2 1.3e-15 57.2 0.9 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EMR61456.1 - 2.5e-11 43.8 0.2 5.5e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Cpn10 PF00166.16 EMR61457.1 - 3.9e-28 97.2 0.0 4.4e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Svf1 PF08622.5 EMR61458.1 - 1.3e-127 425.3 0.1 1.6e-127 424.9 0.1 1.1 1 0 0 1 1 1 1 Svf1-like KH_4 PF13083.1 EMR61458.1 - 0.07 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 KH domain Glyco_hydro_61 PF03443.9 EMR61459.1 - 2.8e-44 151.5 0.0 5.5e-44 150.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Spo7 PF03907.8 EMR61460.1 - 1e-68 231.0 0.0 1.5e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein Pyr_redox_2 PF07992.9 EMR61461.1 - 5e-18 65.7 0.0 1.8e-17 63.8 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR61461.1 - 2.4e-11 43.9 2.1 4.3e-09 36.6 1.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR61461.1 - 5e-06 25.6 0.2 0.00019 20.5 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EMR61461.1 - 4.7e-05 23.5 1.6 0.0014 18.7 1.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR61461.1 - 0.0016 17.4 0.3 1.2 7.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 EMR61461.1 - 0.0065 16.2 0.9 1.7 8.3 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Tricorn_PDZ PF14685.1 EMR61461.1 - 0.025 14.3 1.2 0.095 12.4 0.1 2.4 3 0 0 3 3 3 0 Tricorn protease PDZ domain Lipase_GDSL_2 PF13472.1 EMR61461.1 - 0.027 14.6 1.1 0.063 13.4 0.8 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DAO PF01266.19 EMR61461.1 - 0.18 10.7 10.1 1.6 7.5 0.0 3.3 2 2 1 3 3 3 0 FAD dependent oxidoreductase SNF2_N PF00176.18 EMR61462.1 - 9.2e-69 231.5 0.1 1.4e-68 230.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EMR61462.1 - 2.6e-11 43.1 5.2 2.8e-11 43.0 2.1 2.2 2 0 0 2 2 2 1 Ring finger domain Helicase_C PF00271.26 EMR61462.1 - 3.9e-11 42.6 0.0 1.3e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EMR61462.1 - 2.5e-07 30.2 3.7 6.2e-07 28.9 2.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR61462.1 - 2.7e-07 30.2 3.3 6.5e-07 28.9 2.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMR61462.1 - 8.9e-07 28.8 4.2 8.9e-07 28.8 2.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMR61462.1 - 2e-05 24.3 2.1 5.3e-05 22.9 1.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger HIRAN PF08797.6 EMR61462.1 - 2.3e-05 24.2 0.0 5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-C3HC4_3 PF13920.1 EMR61462.1 - 2.9e-05 23.6 1.4 2.9e-05 23.6 1.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMR61462.1 - 3.9e-05 23.6 2.2 0.00012 22.1 1.5 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EMR61462.1 - 0.00059 19.6 2.9 0.0013 18.5 2.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EMR61462.1 - 0.00064 19.1 1.0 0.0018 17.7 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EMR61462.1 - 0.0012 18.5 0.9 0.0073 16.0 1.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger RINGv PF12906.2 EMR61462.1 - 0.13 12.3 3.8 0.37 10.8 2.6 1.8 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EMR61462.1 - 1 9.3 5.2 0.3 11.0 1.3 1.9 2 0 0 2 2 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EMR61462.1 - 3.3 7.3 7.2 0.58 9.7 1.8 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_L11_N PF03946.9 EMR61463.1 - 5.1e-27 93.1 0.0 1.8e-26 91.3 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EMR61463.1 - 8.2e-24 83.5 0.6 1.6e-23 82.6 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain CDO_I PF05995.7 EMR61464.1 - 1.1e-38 132.1 0.1 1.3e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EMR61464.1 - 0.088 12.1 0.0 0.14 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1637) Adenine_glyco PF03352.8 EMR61465.1 - 0.13 11.8 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Methyladenine glycosylase Abhydrolase_6 PF12697.2 EMR61466.1 - 1.3e-28 100.4 0.0 2.1e-28 99.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR61466.1 - 4.7e-17 62.3 0.0 1.8e-16 60.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR61466.1 - 1.1e-12 47.9 0.0 1.6e-11 44.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EMR61466.1 - 4.8e-05 22.5 0.0 0.00015 20.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EMR61466.1 - 6.6e-05 22.4 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 EMR61466.1 - 0.0002 21.6 0.0 0.002 18.4 0.0 2.2 1 1 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.2 EMR61466.1 - 0.0022 16.9 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.13 EMR61466.1 - 0.0057 15.9 0.0 4 6.6 0.0 2.6 2 1 0 2 2 2 2 Dienelactone hydrolase family Lipase_3 PF01764.20 EMR61466.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.6 EMR61466.1 - 0.016 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.3 EMR61466.1 - 0.025 14.3 0.0 0.078 12.8 0.0 1.8 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 EMR61466.1 - 0.033 13.7 0.0 0.38 10.2 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EMR61466.1 - 0.036 13.5 0.0 7.2 5.9 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF2305 PF10230.4 EMR61466.1 - 0.036 13.4 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Cation_ATPase_N PF00690.21 EMR61466.1 - 0.054 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus PGAP1 PF07819.8 EMR61466.1 - 0.098 12.2 0.0 0.48 9.9 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein adh_short_C2 PF13561.1 EMR61467.1 - 8.4e-27 94.4 0.1 9.9e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR61467.1 - 3.9e-19 69.1 0.7 5.3e-19 68.7 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR61467.1 - 2e-05 24.3 0.3 2.9e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 EMR61467.1 - 0.0011 18.5 0.2 0.0016 18.0 0.1 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus 2-Hacid_dh_C PF02826.14 EMR61467.1 - 0.0062 15.7 0.4 0.014 14.5 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EMR61467.1 - 0.011 16.2 0.3 0.02 15.3 0.2 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Polysacc_deac_2 PF04748.8 EMR61467.1 - 0.024 13.6 0.1 0.038 12.9 0.1 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Epimerase PF01370.16 EMR61467.1 - 0.044 13.2 0.4 0.2 11.0 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EMR61467.1 - 0.055 13.1 0.3 0.087 12.4 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMN_red PF03358.10 EMR61467.1 - 0.072 12.5 0.1 4.1 6.8 0.1 2.4 2 0 0 2 2 2 0 NADPH-dependent FMN reductase NmrA PF05368.8 EMR61467.1 - 0.097 11.9 1.1 0.19 10.9 0.7 1.5 2 0 0 2 2 2 0 NmrA-like family End3 PF12761.2 EMR61468.1 - 9.7e-73 243.9 2.5 1.3e-72 243.5 1.7 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EMR61468.1 - 2.5e-47 158.8 0.0 5.2e-46 154.6 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.1 EMR61468.1 - 2.4e-06 27.0 0.1 6.5e-06 25.6 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMR61468.1 - 2.7e-06 26.2 0.2 2.7e-06 26.2 0.2 2.5 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 EMR61468.1 - 7.4e-05 22.8 0.1 0.00034 20.7 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EMR61468.1 - 0.012 14.9 3.6 0.014 14.6 0.1 2.6 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 EMR61468.1 - 0.018 14.8 0.2 0.018 14.8 0.2 2.5 3 0 0 3 3 3 0 EF-hand domain TBPIP PF07106.8 EMR61468.1 - 2 7.9 6.3 13 5.2 3.2 2.6 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) COG2 PF06148.6 EMR61468.1 - 5.4 6.9 6.9 1.4 8.8 0.5 2.9 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DSPc PF00782.15 EMR61469.1 - 9.7e-14 51.0 0.1 1.7e-13 50.3 0.1 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain RNase_H PF00075.19 EMR61470.1 - 6.7e-15 55.5 0.0 8.6e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EMR61470.1 - 2.8e-06 27.0 0.7 0.0025 17.5 0.0 3.1 3 0 0 3 3 3 2 Reverse transcriptase-like ATP-synt_8 PF00895.15 EMR61471.1 - 0.15 12.2 2.2 0.25 11.5 1.5 1.3 1 0 0 1 1 1 0 ATP synthase protein 8 Lamp PF01299.12 EMR61471.1 - 0.39 9.8 2.3 0.51 9.4 1.6 1.3 1 1 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Velvet PF11754.3 EMR61473.1 - 5.9e-12 45.6 0.4 1.6e-06 27.9 0.1 2.2 1 1 1 2 2 2 2 Velvet factor Pax2_C PF12403.3 EMR61473.1 - 0.018 14.6 1.9 0.024 14.2 1.3 1.2 1 0 0 1 1 1 0 Paired-box protein 2 C terminal RhoGEF PF00621.15 EMR61474.1 - 1.9e-35 122.3 2.4 9e-35 120.1 0.0 2.8 2 1 1 3 3 3 1 RhoGEF domain BAR PF03114.13 EMR61474.1 - 9.1e-11 41.6 1.3 9.1e-11 41.6 0.9 2.6 3 0 0 3 3 3 1 BAR domain MAP7 PF05672.6 EMR61474.1 - 0.016 14.6 48.6 0.042 13.2 33.7 1.7 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family FR47 PF08445.5 EMR61475.1 - 3.5e-06 26.6 0.0 6.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EMR61475.1 - 0.0002 21.5 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR61475.1 - 0.00024 21.2 0.0 0.00052 20.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR61475.1 - 0.00053 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EMR61475.1 - 0.029 14.2 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.5 EMR61475.1 - 0.087 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region DUF3602 PF12223.3 EMR61476.1 - 4.6e-17 62.1 17.7 1.5e-14 54.0 0.9 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) URO-D PF01208.12 EMR61477.1 - 7e-116 386.8 0.0 7.9e-116 386.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Zn_clus PF00172.13 EMR61478.1 - 1.2e-08 34.7 8.0 2.3e-08 33.8 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMR61478.1 - 1.8e-08 33.6 0.1 3.6e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Dickkopf_N PF04706.7 EMR61478.1 - 5.1 7.3 10.2 14 5.9 7.0 1.7 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region AAA_18 PF13238.1 EMR61479.1 - 1.1e-28 100.1 0.2 5.8e-28 97.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMR61479.1 - 1.5e-15 58.1 0.4 2.4e-15 57.4 0.3 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMR61479.1 - 3.7e-06 26.8 0.1 0.0048 16.7 0.0 2.5 2 1 1 3 3 3 2 AAA domain AAA_28 PF13521.1 EMR61479.1 - 8.6e-06 25.8 0.2 4.4e-05 23.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain ADK PF00406.17 EMR61479.1 - 1.1e-05 25.3 0.0 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA PF00004.24 EMR61479.1 - 1.3e-05 25.4 0.0 0.0003 20.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 EMR61479.1 - 3.4e-05 23.7 0.0 0.00018 21.4 0.0 1.9 1 1 0 1 1 1 1 Shikimate kinase NTPase_1 PF03266.10 EMR61479.1 - 0.00032 20.4 0.0 0.00062 19.5 0.0 1.5 1 0 0 1 1 1 1 NTPase Thymidylate_kin PF02223.12 EMR61479.1 - 0.00034 20.0 0.1 0.43 9.9 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_22 PF13401.1 EMR61479.1 - 0.0013 18.9 0.0 0.0055 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 EMR61479.1 - 0.0021 18.0 0.1 0.0056 16.5 0.0 1.8 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_16 PF13191.1 EMR61479.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.5 EMR61479.1 - 0.0097 15.1 0.0 0.039 13.1 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 IstB_IS21 PF01695.12 EMR61479.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.9 EMR61479.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EMR61479.1 - 0.014 14.8 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 EMR61479.1 - 0.02 14.4 0.3 0.045 13.2 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 EMR61479.1 - 0.023 14.4 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 EMR61479.1 - 0.03 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EMR61479.1 - 0.031 14.1 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EMR61479.1 - 0.04 12.7 0.0 0.078 11.7 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_10 PF12846.2 EMR61479.1 - 0.049 13.0 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 EMR61479.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.7 2 0 0 2 2 1 0 RNA helicase Viral_helicase1 PF01443.13 EMR61479.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 EMR61479.1 - 0.08 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMR61479.1 - 0.12 12.6 0.1 0.51 10.6 0.1 1.9 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.17 EMR61479.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 EMR61479.1 - 0.16 10.8 0.4 0.35 9.7 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ArsA_ATPase PF02374.10 EMR61479.1 - 0.18 10.8 0.7 2 7.3 0.1 2.2 1 1 1 2 2 2 0 Anion-transporting ATPase NAP PF00956.13 EMR61480.1 - 2.5e-89 298.6 8.0 2.5e-89 298.6 5.5 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Ham1p_like PF01725.11 EMR61481.1 - 5.7e-52 175.8 0.0 6.4e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DMAP1 PF05499.7 EMR61481.1 - 0.13 11.8 0.1 0.42 10.1 0.0 1.8 3 0 0 3 3 3 0 DNA methyltransferase 1-associated protein 1 (DMAP1) 2-Hacid_dh_C PF02826.14 EMR61482.1 - 1.9e-53 180.2 0.0 2.9e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMR61482.1 - 5.2e-34 116.5 0.1 7.5e-34 116.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMR61482.1 - 3.2e-05 23.8 0.5 7e-05 22.7 0.3 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EMR61482.1 - 0.00019 21.2 0.6 0.00048 19.9 0.1 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 EMR61482.1 - 0.00061 19.1 0.4 0.022 14.0 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain ACT PF01842.20 EMR61482.1 - 0.037 13.5 0.0 0.1 12.0 0.0 1.8 1 0 0 1 1 1 0 ACT domain 3HCDH_N PF02737.13 EMR61482.1 - 0.09 12.4 0.9 0.52 9.9 0.4 2.4 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 EMR61482.1 - 0.096 12.9 0.0 0.32 11.3 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Myosin_head PF00063.16 EMR61483.1 - 2.2e-243 809.3 0.1 2.2e-243 809.3 0.0 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EMR61483.1 - 6.8e-35 119.1 3.4 2.4e-34 117.3 2.3 2.0 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EMR61483.1 - 5.9e-11 40.9 36.5 0.00043 19.6 0.3 7.2 7 0 0 7 7 6 6 IQ calmodulin-binding motif GAS PF13851.1 EMR61483.1 - 0.00011 21.4 31.5 0.012 14.7 21.8 2.8 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding AAA_19 PF13245.1 EMR61483.1 - 0.00084 19.0 0.4 0.014 15.1 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EMR61483.1 - 0.0017 18.5 0.0 0.0095 16.0 0.0 2.3 1 0 0 1 1 1 1 AAA domain Reo_sigmaC PF04582.7 EMR61483.1 - 0.2 10.8 4.3 0.48 9.5 3.0 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EMR61483.1 - 0.38 10.5 8.9 2.3 8.0 6.2 2.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 EMR61483.1 - 0.59 9.9 34.7 3 7.7 5.3 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 EMR61483.1 - 1.1 9.3 25.4 0.29 11.1 8.5 3.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Myosin_N PF02736.14 EMR61483.1 - 1.2 8.8 7.2 0.16 11.6 1.8 2.0 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain FlaC_arch PF05377.6 EMR61483.1 - 9.4 6.2 14.4 0.34 10.8 0.2 4.2 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) GMC_oxred_N PF00732.14 EMR61484.1 - 1.3e-49 168.9 0.0 1.9e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR61484.1 - 2.1e-40 138.3 0.0 3.3e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMR61484.1 - 1.6e-07 30.5 0.1 0.0063 15.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR61484.1 - 2.6e-07 29.8 0.1 0.0001 21.3 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR61484.1 - 1.8e-05 24.6 0.1 9.1e-05 22.4 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMR61484.1 - 5.3e-05 22.2 0.0 8e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMR61484.1 - 0.0025 17.7 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR61484.1 - 0.0063 16.8 0.0 0.17 12.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMR61484.1 - 0.0079 15.3 0.1 0.46 9.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMR61484.1 - 0.012 14.2 0.2 0.031 12.9 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 EMR61484.1 - 0.025 13.0 0.1 0.11 10.9 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein DEAD PF00270.24 EMR61485.1 - 1.5e-45 154.6 0.1 7.2e-45 152.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EMR61485.1 - 2.8e-26 90.8 0.0 5.9e-26 89.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EMR61485.1 - 2.1e-19 69.1 0.0 4.3e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR61485.1 - 0.00045 20.1 1.1 0.021 14.6 0.0 3.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Aldedh PF00171.17 EMR61486.1 - 4.5e-151 503.2 0.1 5.6e-151 502.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4633 PF15464.1 EMR61486.1 - 0.19 11.6 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) Anoctamin PF04547.7 EMR61487.1 - 3.2e-95 319.4 0.2 3.8e-95 319.2 0.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel PAPS_reduct PF01507.14 EMR61488.1 - 7.9e-30 103.9 0.0 2.2e-29 102.4 0.0 1.8 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Sad1_UNC PF07738.8 EMR61489.1 - 6.1e-07 29.3 0.3 1e-05 25.3 0.2 2.2 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Baculo_PEP_C PF04513.7 EMR61489.1 - 0.0016 18.3 0.1 0.0033 17.2 0.1 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus ORF6C PF10552.4 EMR61489.1 - 0.04 13.6 1.6 0.06 13.0 0.5 1.7 2 0 0 2 2 2 0 ORF6C domain Erp_C PF06780.6 EMR61489.1 - 0.063 13.1 8.2 0.081 12.7 3.6 2.5 1 1 2 3 3 3 0 Erp protein C-terminus Methyltrn_RNA_2 PF04013.7 EMR61489.1 - 0.072 12.6 0.2 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase FliL PF03748.9 EMR61489.1 - 0.14 12.1 0.9 0.92 9.5 0.6 2.1 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL MgtE_N PF03448.12 EMR61490.1 - 0.0032 17.7 2.0 0.08 13.2 1.3 2.4 1 1 0 1 1 1 1 MgtE intracellular N domain MBOAT_2 PF13813.1 EMR61490.1 - 0.0064 16.5 7.9 45 4.2 5.5 3.4 1 1 0 1 1 1 0 Membrane bound O-acyl transferase family DUF2884 PF11101.3 EMR61490.1 - 0.015 14.6 10.7 1 8.6 7.4 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) DUF697 PF05128.7 EMR61490.1 - 0.015 14.7 2.3 2.8 7.3 1.6 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF697) Trigger_C PF05698.9 EMR61490.1 - 0.6 9.9 5.3 6.2 6.6 0.6 2.3 1 1 1 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus ABC_membrane_2 PF06472.10 EMR61490.1 - 0.86 8.6 14.5 1.5 7.8 4.0 2.1 1 1 1 2 2 2 0 ABC transporter transmembrane region 2 IpaB_EvcA PF03278.8 EMR61490.1 - 1.1 8.4 3.5 4.9 6.3 0.5 2.2 1 1 1 2 2 2 0 IpaB/EvcA family Epimerase PF01370.16 EMR61491.1 - 1.5e-44 152.1 0.0 2.1e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EMR61491.1 - 3.8e-25 87.6 0.1 6.9e-25 86.7 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EMR61491.1 - 1.7e-17 63.0 0.0 6.5e-17 61.1 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMR61491.1 - 5.8e-13 48.3 0.0 6.3e-11 41.7 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EMR61491.1 - 5.9e-12 45.0 0.0 8.9e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EMR61491.1 - 9.1e-11 41.9 0.0 1.4e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EMR61491.1 - 1.9e-08 33.5 0.0 4.3e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EMR61491.1 - 4.6e-07 29.6 0.0 9.3e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR61491.1 - 1.5e-06 28.3 0.0 2.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 EMR61491.1 - 0.00097 18.5 0.2 0.0027 17.1 0.1 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 EMR61491.1 - 0.0015 19.0 0.0 2 9.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain NmrA PF05368.8 EMR61491.1 - 0.0025 17.1 0.0 0.021 14.0 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family DAO PF01266.19 EMR61491.1 - 0.0098 14.8 0.3 0.017 14.0 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EMR61491.1 - 0.05 13.2 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Phage_lysozyme PF00959.14 EMR61491.1 - 0.058 13.6 0.1 0.58 10.4 0.0 2.2 2 0 0 2 2 2 0 Phage lysozyme NAC PF01849.13 EMR61492.1 - 9.9e-07 28.1 0.4 1.9e-06 27.2 0.1 1.6 2 0 0 2 2 2 1 NAC domain DLIC PF05783.6 EMR61492.1 - 0.046 12.3 0.2 0.052 12.2 0.1 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) P12 PF12669.2 EMR61493.1 - 0.0033 17.5 0.8 3.6 7.8 0.0 2.2 2 0 0 2 2 2 2 Virus attachment protein p12 family BUD22 PF09073.5 EMR61493.1 - 0.086 11.8 4.7 0.1 11.6 3.3 1.1 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.1 EMR61493.1 - 0.14 11.7 2.0 4 7.0 2.2 2.1 2 0 0 2 2 2 0 FAM176 family Nucleoplasmin PF03066.10 EMR61493.1 - 0.18 11.3 4.3 0.22 11.0 3.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EMR61493.1 - 0.57 8.1 4.5 0.71 7.8 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 EMR61493.1 - 0.64 10.2 12.8 1.5 9.1 8.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 EMR61493.1 - 0.73 7.6 9.0 0.74 7.6 6.2 1.0 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EMR61493.1 - 1.6 8.4 6.3 1.7 8.2 4.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.7 EMR61493.1 - 2.2 7.4 10.0 0.17 11.0 3.9 1.4 2 0 0 2 2 2 0 NOA36 protein Daxx PF03344.10 EMR61493.1 - 2.7 6.3 6.9 3.2 6.1 4.8 1.1 1 0 0 1 1 1 0 Daxx Family ANAPC15 PF15243.1 EMR61493.1 - 3.9 7.6 11.0 8.6 6.5 7.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 S-antigen PF05756.6 EMR61493.1 - 6.2 6.8 8.1 4.1 7.4 4.1 1.8 2 0 0 2 2 2 0 S-antigen protein EPSP_synthase PF00275.15 EMR61494.1 - 1.6e-130 435.3 0.0 2.4e-130 434.7 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EMR61494.1 - 8.4e-100 333.0 0.0 1.4e-99 332.3 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EMR61494.1 - 2.2e-65 220.4 0.0 5.2e-65 219.2 0.0 1.7 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.17 EMR61494.1 - 1.9e-38 131.8 0.0 9.6e-37 126.2 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EMR61494.1 - 1.1e-23 83.0 0.0 2.9e-23 81.7 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EMR61494.1 - 8.1e-12 45.4 0.0 2.8e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EMR61494.1 - 5.2e-09 35.7 0.0 9.2e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EMR61494.1 - 0.00029 21.6 0.0 0.001 19.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMR61494.1 - 0.065 13.1 0.0 0.54 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EMR61494.1 - 0.075 12.4 0.2 0.19 11.1 0.2 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF770 PF05591.7 EMR61494.1 - 0.16 11.4 0.1 0.62 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF770) Histone PF00125.19 EMR61495.1 - 3.6e-31 107.0 0.4 5.8e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EMR61495.1 - 4.1e-06 26.8 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMR61495.1 - 0.004 17.1 0.3 0.0074 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMR61495.1 - 0.014 15.1 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF1227 PF06777.6 EMR61496.1 - 1.9e-60 202.8 0.5 4.3e-60 201.6 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EMR61496.1 - 1.3e-51 174.4 0.1 2.2e-51 173.7 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EMR61496.1 - 2.9e-43 147.7 0.0 1.1e-42 145.8 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain SNF2_N PF00176.18 EMR61496.1 - 0.00011 21.1 0.0 0.00062 18.6 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_11 PF13086.1 EMR61496.1 - 0.0018 17.8 0.1 0.0056 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EMR61496.1 - 0.004 16.9 0.0 0.015 15.1 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMR61496.1 - 0.0044 16.5 0.0 0.37 10.2 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 EMR61496.1 - 0.04 13.1 0.0 3.9 6.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF3829 PF12889.2 EMR61496.1 - 0.09 11.9 0.1 6.2 5.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Beta-Casp PF10996.3 EMR61496.1 - 0.094 12.6 0.3 7.7 6.4 0.0 3.1 3 0 0 3 3 3 0 Beta-Casp domain RNA_pol_Rpb1_5 PF04998.12 EMR61498.1 - 2.6e-87 292.5 0.0 1.6e-86 289.9 0.0 2.4 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EMR61498.1 - 4.2e-64 215.4 0.1 1.1e-63 214.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EMR61498.1 - 6.4e-30 103.9 0.0 2.2e-29 102.2 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EMR61498.1 - 1.7e-17 63.1 0.0 7.3e-17 61.0 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 EMR61498.1 - 9.7e-14 51.3 1.2 1.1e-06 28.2 2.2 2.7 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 1 Nop14 PF04147.7 EMR61498.1 - 7.8 4.2 24.9 0.37 8.6 10.3 2.1 2 0 0 2 2 2 0 Nop14-like family PRP3 PF08572.5 EMR61499.1 - 5.4e-72 241.7 4.3 7.7e-72 241.2 3.0 1.2 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EMR61499.1 - 2.7e-32 111.1 0.0 6.4e-32 109.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Histone PF00125.19 EMR61500.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EMR61500.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EMR61500.1 - 0.00012 22.1 0.1 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMR61500.1 - 0.00033 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMR61500.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EMR61500.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T AMP-binding PF00501.23 EMR61501.1 - 1e-72 244.8 0.1 3.4e-72 243.1 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EMR61501.1 - 2e-64 216.9 0.0 3.1e-64 216.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EMR61501.1 - 3e-10 39.9 0.0 9.9e-10 38.2 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMR61501.1 - 1.1e-07 32.0 0.0 2.2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EMR61501.1 - 1.5e-07 32.2 0.0 7.2e-07 30.0 0.0 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 EMR61501.1 - 0.00031 20.7 0.0 0.0017 18.3 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMR61501.1 - 0.00091 18.0 0.0 0.0017 17.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMR61501.1 - 0.012 14.4 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EMR61501.1 - 0.027 14.3 2.3 0.042 13.7 0.3 2.4 2 1 0 2 2 2 0 short chain dehydrogenase DUF726 PF05277.7 EMR61502.1 - 6.1e-118 393.6 0.3 9e-118 393.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 EMR61502.1 - 0.00023 21.4 0.0 0.0008 19.7 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EMR61502.1 - 0.00023 21.1 0.3 0.0005 20.0 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pro-NT_NN PF07421.6 EMR61502.1 - 0.0068 15.9 0.0 0.026 14.0 0.0 2.0 2 0 0 2 2 2 1 Neurotensin/neuromedin N precursor Abhydrolase_5 PF12695.2 EMR61502.1 - 0.013 15.2 0.1 0.013 15.2 0.1 2.1 2 1 0 2 2 2 0 Alpha/beta hydrolase family Cutinase PF01083.17 EMR61502.1 - 0.029 14.1 0.1 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Cutinase PE-PPE PF08237.6 EMR61502.1 - 0.038 13.4 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Tubulin_C PF03953.12 EMR61502.1 - 0.048 13.7 0.4 0.11 12.5 0.3 1.6 1 0 0 1 1 1 0 Tubulin C-terminal domain Tyrosinase PF00264.15 EMR61503.1 - 4.8e-54 183.8 0.1 7.1e-54 183.3 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase HEAT PF02985.17 EMR61504.1 - 1.2e-06 28.0 1.4 0.072 13.2 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EMR61504.1 - 0.00073 19.7 0.3 0.032 14.5 0.1 4.9 5 1 1 6 6 6 2 HEAT repeats WHG PF13305.1 EMR61504.1 - 0.12 13.0 0.0 3.1 8.4 0.0 3.3 2 0 0 2 2 2 0 WHG domain Glyco_hydro_49 PF03718.8 EMR61504.1 - 0.12 10.4 0.0 0.18 9.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 HEAT_EZ PF13513.1 EMR61504.1 - 0.17 12.4 2.7 1.6 9.2 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat HK PF02110.10 EMR61505.1 - 1.4e-69 234.0 4.3 2e-69 233.4 3.0 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EMR61505.1 - 7e-56 188.1 0.2 1.2e-55 187.4 0.1 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Acetyltransf_3 PF13302.1 EMR61506.1 - 2e-15 57.2 0.0 3.3e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR61506.1 - 5.8e-07 29.4 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EMR61506.1 - 0.00014 21.7 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMR61506.1 - 0.085 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BP28CT PF08146.7 EMR61509.1 - 2e-44 151.0 2.1 7.5e-44 149.1 0.2 2.9 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EMR61509.1 - 1.2e-23 83.3 0.1 1.2e-23 83.3 0.0 5.4 5 2 1 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EMR61509.1 - 1e-06 28.9 12.4 0.84 9.9 0.6 7.7 8 2 0 8 8 8 3 HEAT repeats HEAT PF02985.17 EMR61509.1 - 0.00031 20.5 14.3 0.52 10.5 0.1 6.4 6 0 0 6 6 6 2 HEAT repeat CactinC_cactus PF09732.4 EMR61509.1 - 0.14 11.7 0.0 4 7.0 0.0 2.3 2 0 0 2 2 2 0 Cactus-binding C-terminus of cactin protein HEAT_EZ PF13513.1 EMR61509.1 - 2.4 8.7 22.7 37 4.9 0.0 8.8 7 2 3 10 10 10 0 HEAT-like repeat Helicase_C PF00271.26 EMR61511.1 - 2.7e-20 72.0 0.0 1.2e-16 60.3 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EMR61511.1 - 1.1e-14 54.3 0.0 4.8e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Arm PF00514.18 EMR61511.1 - 0.21 11.4 0.9 0.59 10.0 0.1 2.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Daxx PF03344.10 EMR61512.1 - 0.069 11.6 6.7 0.11 10.9 4.6 1.3 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 EMR61512.1 - 8 5.6 13.2 12 4.9 9.2 1.2 1 0 0 1 1 1 0 NOA36 protein Pyr_redox_2 PF07992.9 EMR61513.1 - 1.6e-38 132.6 1.0 2.7e-38 131.8 0.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EMR61513.1 - 6.1e-33 113.1 0.1 2.6e-32 111.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EMR61513.1 - 7.5e-18 64.7 0.9 8.5e-16 58.1 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR61513.1 - 9.2e-11 42.1 0.1 1.4e-09 38.3 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR61513.1 - 0.00027 19.5 2.9 1.8 6.9 1.0 3.1 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.1 EMR61513.1 - 0.00058 18.8 0.0 0.0039 16.1 0.0 1.9 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 EMR61513.1 - 0.00099 18.2 0.1 0.0023 17.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EMR61513.1 - 0.016 14.1 0.2 0.039 12.8 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.19 EMR61513.1 - 0.03 13.2 0.6 0.1 11.5 0.2 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EMR61513.1 - 0.035 13.1 0.3 0.07 12.2 0.2 1.5 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 EMR61513.1 - 0.037 13.6 0.5 0.27 10.8 0.0 2.6 2 1 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EMR61513.1 - 0.043 13.8 2.0 0.11 12.5 1.4 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 EMR61513.1 - 0.044 13.3 0.5 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EMR61513.1 - 0.21 10.7 2.2 1.7 7.7 0.0 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EMR61513.1 - 0.27 10.0 3.5 0.44 9.3 1.9 1.7 2 0 0 2 2 2 0 FAD binding domain LsmAD PF06741.8 EMR61514.1 - 1.2e-22 79.8 2.2 1.2e-22 79.8 1.5 2.7 3 0 0 3 3 3 2 LsmAD domain DUF677 PF05055.7 EMR61514.1 - 0.0089 14.7 0.3 0.016 13.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF677) Sulfatase_C PF14707.1 EMR61514.1 - 7.1 6.9 7.7 12 6.2 1.0 2.6 3 0 0 3 3 3 0 C-terminal region of aryl-sulfatase Ydc2-catalyt PF09159.5 EMR61515.1 - 3.2e-66 223.6 0.0 3.8e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.22 EMR61515.1 - 0.00033 20.0 0.0 0.00075 18.9 0.0 1.6 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.8 EMR61515.1 - 0.00039 20.2 0.0 0.86 9.4 0.0 3.3 3 1 0 3 3 3 2 Poxvirus A22 protein Ribosomal_L22 PF00237.14 EMR61517.1 - 1.7e-14 53.6 0.0 6.5e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e DUF2797 PF10977.3 EMR61517.1 - 0.19 11.3 2.9 1.8 8.1 2.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2797) CFEM PF05730.6 EMR61518.1 - 1.4e-08 34.4 5.1 1.9e-08 34.0 3.6 1.3 1 1 0 1 1 1 1 CFEM domain TIL PF01826.12 EMR61518.1 - 0.28 11.3 8.2 0.085 12.9 3.7 1.6 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain 2OG-FeII_Oxy_2 PF13532.1 EMR61519.1 - 1.4e-23 83.7 0.0 2e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nucleo_P87 PF07267.6 EMR61519.1 - 1.1 7.8 4.0 5.6 5.5 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 RXT2_N PF08595.6 EMR61519.1 - 3.5 7.4 9.2 3.6 7.3 1.0 2.8 2 0 0 2 2 2 0 RXT2-like, N-terminal STE2 PF02116.10 EMR61520.1 - 6.1e-30 104.2 0.0 7.9e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Isochorismatase PF00857.15 EMR61521.1 - 3e-26 92.4 0.0 9e-26 90.8 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family Herpes_LMP1 PF05297.6 EMR61521.1 - 0.26 10.1 7.8 0.4 9.5 5.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ribosomal_60s PF00428.14 EMR61521.1 - 3.6 8.0 16.3 0.17 12.3 2.4 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein LRR_4 PF12799.2 EMR61522.1 - 1.5e-17 62.8 0.6 2.6e-05 23.7 0.1 4.5 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMR61522.1 - 1e-15 57.2 2.2 2.4e-08 33.5 0.3 3.9 3 1 1 4 4 4 3 Leucine rich repeat Pkinase_Tyr PF07714.12 EMR61522.1 - 4.5e-15 55.4 0.0 2.9e-14 52.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EMR61522.1 - 1.2e-14 54.0 0.0 1.9e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_1 PF00560.28 EMR61522.1 - 2.9e-10 38.7 3.2 0.0053 16.5 0.0 6.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EMR61522.1 - 4.1e-06 26.1 5.7 0.53 10.7 0.1 5.9 6 0 0 6 6 6 1 Leucine rich repeat Kdo PF06293.9 EMR61522.1 - 4.5e-05 22.6 3.1 9.1e-05 21.6 2.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMR61522.1 - 0.0074 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_6 PF13516.1 EMR61522.1 - 0.016 15.2 0.3 4.6 7.6 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat DUF515 PF04415.7 EMR61522.1 - 0.31 9.2 1.9 0.46 8.6 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Bromo_TP PF07524.8 EMR61523.1 - 5.6e-16 58.0 0.0 5.3e-15 54.9 0.0 2.2 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.4 EMR61523.1 - 9.6e-12 44.7 0.2 3.3e-11 43.0 0.1 1.9 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Glutaredoxin2_C PF04399.8 EMR61523.1 - 0.13 11.8 0.6 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain WD40 PF00400.27 EMR61524.1 - 1.8e-61 201.9 25.9 1.2e-11 43.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EMR61524.1 - 5.9e-05 21.4 7.3 0.25 9.4 0.1 4.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EMR61524.1 - 0.016 13.5 0.0 3.7 5.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain mRNA_stabil PF13929.1 EMR61524.1 - 0.11 11.4 0.1 0.33 9.8 0.0 1.7 2 0 0 2 2 2 0 mRNA stabilisation Sugar_tr PF00083.19 EMR61525.1 - 1.3e-77 261.2 25.1 1.6e-77 261.0 17.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR61525.1 - 5.8e-17 61.4 29.6 1.2e-13 50.5 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro-kuma_activ PF09286.6 EMR61526.1 - 1.2e-41 142.1 0.0 6.2e-41 139.7 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EMR61526.1 - 1.1e-05 24.8 1.2 1.8e-05 24.0 0.9 1.4 1 0 0 1 1 1 1 Subtilase family Disintegrin PF00200.18 EMR61527.1 - 9.4e-17 61.0 37.3 9.4e-17 61.0 25.9 3.9 3 1 2 5 5 5 1 Disintegrin Reprolysin_2 PF13574.1 EMR61527.1 - 0.0054 16.7 2.7 0.016 15.2 0.0 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like GRP PF07172.6 EMR61527.1 - 8.1 6.9 16.5 0.56 10.7 7.4 2.1 2 0 0 2 2 2 0 Glycine rich protein family Glyco_hydro_16 PF00722.16 EMR61529.1 - 2.2e-41 141.1 1.6 3.8e-41 140.4 1.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 p450 PF00067.17 EMR61530.1 - 2.1e-58 197.9 0.0 1.9e-57 194.8 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF258 PF03193.11 EMR61531.1 - 1.8e-08 33.7 0.5 2.6e-07 29.9 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EMR61531.1 - 2e-08 34.1 0.1 6.8e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EMR61531.1 - 1.5e-05 24.1 0.0 0.14 11.2 0.0 3.2 3 0 0 3 3 3 2 AIG1 family FtsK_SpoIIIE PF01580.13 EMR61531.1 - 0.0002 20.9 0.3 0.0013 18.2 0.0 2.4 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_29 PF13555.1 EMR61531.1 - 0.00056 19.3 0.1 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 EMR61531.1 - 0.0011 18.8 1.7 0.59 9.9 0.0 2.9 3 0 0 3 3 2 2 Dynamin family Septin PF00735.13 EMR61531.1 - 0.0021 17.1 0.1 0.0071 15.3 0.1 1.9 1 1 0 1 1 1 1 Septin AAA_23 PF13476.1 EMR61531.1 - 0.0025 18.1 1.6 0.012 15.9 1.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR61531.1 - 0.0048 16.9 0.0 0.016 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain IIGP PF05049.8 EMR61531.1 - 0.0072 15.1 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) T2SE PF00437.15 EMR61531.1 - 0.0072 15.2 0.0 0.019 13.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 EMR61531.1 - 0.0075 16.5 0.2 0.064 13.5 0.0 2.7 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.22 EMR61531.1 - 0.0081 15.6 0.1 0.023 14.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMR61531.1 - 0.0093 16.1 0.0 0.75 9.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EMR61531.1 - 0.022 14.2 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 EMR61531.1 - 0.035 13.5 0.8 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain Miro PF08477.8 EMR61531.1 - 0.035 14.5 0.0 0.25 11.8 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 EMR61531.1 - 0.049 13.8 0.1 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 EMR61531.1 - 0.078 12.6 0.0 0.26 11.0 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EMR61531.1 - 0.26 11.0 2.7 0.31 10.8 0.1 2.4 4 0 0 4 4 4 0 Domain of unknown function DUF87 ATP-synt PF00231.14 EMR61532.1 - 1.3e-72 244.6 5.0 1.5e-72 244.4 3.4 1.0 1 0 0 1 1 1 1 ATP synthase ORC6 PF05460.8 EMR61533.1 - 0.012 14.6 0.2 0.018 14.1 0.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TEBP_beta PF07404.6 EMR61533.1 - 4.5 6.3 8.9 5.9 5.9 6.1 1.2 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) CAF-1_p150 PF11600.3 EMR61534.1 - 0.00062 19.2 36.3 0.00062 19.2 25.2 1.7 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Borrelia_P83 PF05262.6 EMR61534.1 - 8.4 4.5 26.0 14 3.8 18.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein CorA PF01544.13 EMR61535.1 - 8.7e-13 47.9 3.5 1e-12 47.7 2.4 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3169 PF11368.3 EMR61535.1 - 0.0029 16.8 0.1 0.0034 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) TcpE PF12648.2 EMR61535.1 - 0.029 14.5 3.2 0.041 14.0 2.2 1.3 1 0 0 1 1 1 0 TcpE family Adeno_E4 PF05385.6 EMR61537.1 - 0.047 13.6 0.0 0.061 13.2 0.0 1.1 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein Sec1 PF00995.18 EMR61539.1 - 2.2e-70 237.9 0.0 2.7e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family ABM PF03992.11 EMR61540.1 - 2.6e-11 43.3 0.0 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase AAA_2 PF07724.9 EMR61542.1 - 5.2e-13 49.2 0.0 1.6e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EMR61542.1 - 1.2e-11 44.4 0.0 1.9e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EMR61542.1 - 6.2e-07 29.6 0.0 1.3e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EMR61542.1 - 0.00017 20.8 0.0 0.24 10.5 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ClpB_D2-small PF10431.4 EMR61542.1 - 0.0015 18.3 0.1 0.0041 16.9 0.1 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_17 PF13207.1 EMR61542.1 - 0.0022 18.8 0.1 0.017 15.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EMR61542.1 - 0.0053 16.2 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 EMR61542.1 - 0.03 14.2 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.2 EMR61542.1 - 0.049 13.1 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_22 PF13401.1 EMR61542.1 - 0.066 13.3 0.1 0.59 10.2 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 EMR61542.1 - 0.097 12.6 0.2 8.1 6.3 0.0 2.7 1 1 2 3 3 3 0 AAA ATPase domain Topoisom_I_N PF02919.10 EMR61543.1 - 1.8e-96 321.5 3.6 1.8e-96 321.5 2.5 2.8 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EMR61543.1 - 1.8e-86 289.0 8.1 6.9e-86 287.1 5.6 2.0 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EMR61543.1 - 2.6e-31 107.1 0.3 7.1e-31 105.6 0.2 1.8 1 0 0 1 1 1 1 C-terminal topoisomerase domain Aminotran_1_2 PF00155.16 EMR61544.1 - 3.5e-14 52.5 0.0 6.1e-14 51.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EMR61544.1 - 0.00055 18.6 0.0 0.0028 16.2 0.0 1.9 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EMR61544.1 - 0.082 11.9 0.0 0.32 9.9 0.0 1.8 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family NmrA PF05368.8 EMR61545.1 - 1.6e-35 122.4 0.0 2.3e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR61545.1 - 1.1e-18 67.8 0.0 1.6e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EMR61545.1 - 0.15 12.1 0.1 0.45 10.5 0.1 1.9 1 1 0 1 1 1 0 TrkA-N domain Amino_oxidase PF01593.19 EMR61546.1 - 2.2e-69 234.7 0.4 3.3e-69 234.0 0.0 1.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HMG_box PF00505.14 EMR61546.1 - 6.2e-07 29.6 1.0 6.2e-07 29.6 0.7 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMR61546.1 - 1.2e-06 28.7 1.6 2.4e-06 27.7 1.1 1.5 1 0 0 1 1 1 1 HMG-box domain tRNA-synt_His PF13393.1 EMR61547.1 - 1.3e-41 142.6 0.0 4e-35 121.3 0.0 2.3 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EMR61547.1 - 3.7e-18 65.6 0.0 5.9e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMR61547.1 - 1.2e-12 47.5 0.0 2.9e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EMR61547.1 - 6.2e-05 21.9 0.0 0.0032 16.2 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Spectrin PF00435.16 EMR61548.1 - 0.1 12.9 18.9 0.45 10.8 1.9 2.8 2 1 1 3 3 3 0 Spectrin repeat LPP PF04728.8 EMR61548.1 - 0.32 10.8 6.4 3.4 7.5 0.1 3.9 3 1 1 4 4 4 0 Lipoprotein leucine-zipper Uds1 PF15456.1 EMR61548.1 - 0.8 9.7 20.6 0.11 12.4 1.9 2.8 2 1 1 3 3 3 0 Up-regulated During Septation SOBP PF15279.1 EMR61548.1 - 1.8 8.8 6.9 2.3 8.5 4.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Syntaxin-6_N PF09177.6 EMR61548.1 - 1.9 8.9 12.1 4.3 7.8 2.9 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal MxiH PF09392.5 EMR61548.1 - 2.6 8.6 10.5 0.58 10.7 1.2 2.9 2 1 1 3 3 3 0 Type III secretion needle MxiH like PIN_2 PF10130.4 EMR61548.1 - 4.7 7.2 6.7 19 5.2 0.2 2.8 2 1 1 3 3 3 0 PIN domain IncA PF04156.9 EMR61548.1 - 6.2 6.3 24.1 1.3 8.5 3.2 2.2 2 0 0 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 EMR61548.1 - 8 5.5 10.0 7 5.7 0.9 2.0 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF2813 PF11398.3 EMR61548.1 - 8.8 5.2 14.7 0.5 9.3 1.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2813) Pkinase PF00069.20 EMR61549.1 - 5.7e-71 238.6 0.0 8.2e-71 238.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR61549.1 - 9e-35 119.9 0.1 1.5e-34 119.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR61549.1 - 2.4e-05 23.4 0.0 3.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMR61549.1 - 0.0013 17.8 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMR61549.1 - 0.0063 15.8 0.1 0.019 14.2 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL UQ_con PF00179.21 EMR61550.1 - 1.9e-34 118.0 0.0 2.7e-21 75.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.17 EMR61550.1 - 0.0044 16.8 0.0 1.5 8.6 0.0 2.6 2 1 0 2 2 2 2 RWD domain Cep57_MT_bd PF06657.8 EMR61550.1 - 0.075 12.9 1.0 22 5.0 0.0 3.2 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF2417 PF10329.4 EMR61551.1 - 3.2e-82 275.4 2.4 4.2e-82 275.0 1.7 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EMR61551.1 - 1e-06 28.8 0.5 2e-06 27.8 0.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Scs3p PF10261.4 EMR61551.1 - 0.038 13.0 1.9 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM Ribosomal_L29 PF00831.18 EMR61552.1 - 3.1e-16 58.7 1.6 3.1e-16 58.7 1.1 2.3 2 0 0 2 2 2 1 Ribosomal L29 protein 3Beta_HSD PF01073.14 EMR61553.1 - 4e-65 219.3 0.0 5e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMR61553.1 - 2.2e-31 109.1 1.4 2.2e-31 109.1 0.4 1.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR61553.1 - 2.1e-15 57.1 0.5 3e-15 56.7 0.4 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMR61553.1 - 1.9e-14 53.1 1.6 2.4e-12 46.3 1.1 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EMR61553.1 - 2.7e-14 52.7 1.0 3.7e-14 52.3 0.7 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EMR61553.1 - 8.8e-08 32.2 1.7 2e-07 31.1 1.2 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EMR61553.1 - 2.8e-06 26.7 0.1 4.1e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EMR61553.1 - 1.1e-05 24.4 0.1 3.6e-05 22.8 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EMR61553.1 - 2e-05 24.5 0.1 7.5e-05 22.7 0.0 2.0 1 1 1 2 2 2 1 TrkA-N domain KR PF08659.5 EMR61553.1 - 0.00081 19.0 2.6 0.0035 17.0 1.8 2.0 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EMR61553.1 - 0.007 15.3 0.3 0.013 14.5 0.2 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EMR61553.1 - 0.013 15.4 0.0 0.034 14.0 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.11 EMR61553.1 - 0.061 13.7 0.1 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ATP-synt_10 PF05176.9 EMR61555.1 - 3.6e-67 226.2 0.0 4.2e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein PPR_2 PF13041.1 EMR61556.1 - 1.5e-10 40.8 0.1 0.027 14.4 0.0 4.6 4 0 0 4 4 4 4 PPR repeat family PPR_3 PF13812.1 EMR61556.1 - 0.00064 19.8 0.0 22 5.6 0.0 4.9 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 EMR61556.1 - 0.0011 18.8 0.2 20 5.4 0.0 4.3 4 0 0 4 4 4 2 PPR repeat V-SNARE_C PF12352.3 EMR61557.1 - 1.2e-13 50.9 0.2 1.2e-13 50.9 0.1 3.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus UPF0184 PF03670.8 EMR61557.1 - 0.32 11.1 2.7 3.2 7.9 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) FTA4 PF13093.1 EMR61557.1 - 0.48 9.8 6.4 1.6 8.0 4.4 2.0 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 RhoGAP PF00620.22 EMR61558.1 - 2.6e-07 30.3 0.1 0.0012 18.4 0.0 2.4 1 1 1 2 2 2 2 RhoGAP domain Sec66 PF09802.4 EMR61559.1 - 8e-80 266.7 0.3 9.3e-80 266.5 0.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 AAA PF00004.24 EMR61560.1 - 5.5e-16 58.9 0.0 3.3e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EMR61560.1 - 3.3e-13 49.5 0.1 2.8e-07 30.3 0.0 2.8 3 0 0 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.10 EMR61560.1 - 8.5e-13 47.8 0.1 7.3e-09 34.8 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 EMR61560.1 - 7.3e-11 41.9 0.1 1.7e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain RuvB_N PF05496.7 EMR61560.1 - 3.3e-07 29.5 0.0 8e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMR61560.1 - 3.6e-07 30.3 0.1 0.00045 20.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMR61560.1 - 1.3e-05 24.8 0.0 3.8e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EMR61560.1 - 2.4e-05 24.0 0.0 3.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR61560.1 - 2.6e-05 24.3 0.0 0.0013 18.7 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain DNA_pol3_delta PF06144.8 EMR61560.1 - 0.00015 21.3 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 EMR61560.1 - 0.00021 20.4 0.0 0.0096 15.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EMR61560.1 - 0.00059 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMR61560.1 - 0.0027 17.1 0.5 0.022 14.1 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EMR61560.1 - 0.0032 18.2 0.0 0.01 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EMR61560.1 - 0.0032 16.4 0.0 0.0049 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EMR61560.1 - 0.0054 16.4 1.1 0.13 11.9 0.1 3.1 2 2 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EMR61560.1 - 0.0057 16.2 2.6 0.0078 15.8 0.3 2.4 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EMR61560.1 - 0.0061 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 EMR61560.1 - 0.014 14.8 0.0 0.035 13.5 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EMR61560.1 - 0.017 15.4 0.0 0.044 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMR61560.1 - 0.022 14.6 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EMR61560.1 - 0.025 14.1 0.1 0.41 10.2 0.0 2.8 2 2 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMR61560.1 - 0.05 13.0 0.2 1.2 8.5 0.0 2.6 2 1 1 3 3 3 0 AAA-like domain AAA_33 PF13671.1 EMR61560.1 - 0.062 13.1 0.0 0.19 11.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain DEAD PF00270.24 EMR61560.1 - 0.07 12.6 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_3 PF07726.6 EMR61560.1 - 0.073 12.6 0.0 0.45 10.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EMR61560.1 - 0.081 12.6 0.0 0.33 10.6 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase ResIII PF04851.10 EMR61560.1 - 0.084 12.6 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 EMR61560.1 - 0.092 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 EMR61560.1 - 0.1 11.3 0.0 2.6 6.7 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain HMG_box_2 PF09011.5 EMR61561.1 - 2.3e-08 34.2 0.1 2.3e-08 34.2 0.1 3.0 3 0 0 3 3 3 1 HMG-box domain HMG_box PF00505.14 EMR61561.1 - 2.8e-06 27.4 4.7 6e-06 26.4 1.4 2.9 2 1 0 2 2 2 1 HMG (high mobility group) box Med3 PF11593.3 EMR61561.1 - 1.1 8.3 21.3 1.8 7.7 14.8 1.3 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Nop14 PF04147.7 EMR61562.1 - 2.2e-05 22.6 7.4 2.7e-05 22.3 5.1 1.3 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 EMR61562.1 - 0.029 12.4 15.2 0.059 11.3 10.6 1.5 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EMR61562.1 - 1.7 7.8 19.8 3 7.0 13.8 1.3 1 0 0 1 1 1 0 SDA1 NST1 PF13945.1 EMR61562.1 - 2.9 7.9 17.8 0.57 10.2 8.3 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator YL1 PF05764.8 EMR61562.1 - 5.2 6.6 27.5 1.8 8.0 17.0 1.6 2 0 0 2 2 2 0 YL1 nuclear protein FLO_LFY PF01698.11 EMR61562.1 - 5.8 5.6 13.4 11 4.6 9.3 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Glyco_hydro_38 PF01074.17 EMR61563.1 - 2.5e-91 305.7 1.3 4.2e-91 305.0 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EMR61563.1 - 1.5e-70 238.2 0.0 4.5e-70 236.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EMR61563.1 - 1e-25 89.7 0.0 2.1e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain DEAD PF00270.24 EMR61564.1 - 4.8e-46 156.3 0.0 4e-45 153.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR61564.1 - 5.4e-24 83.8 0.0 1.3e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMR61564.1 - 0.00014 20.7 0.0 0.00025 19.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EMR61564.1 - 0.0049 16.7 0.0 0.021 14.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MutS_III PF05192.13 EMR61565.1 - 2.7e-35 121.9 1.9 4.5e-35 121.3 1.3 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EMR61565.1 - 1.2e-18 67.1 0.0 2.2e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EMR61565.1 - 1.5e-09 38.0 0.0 5.7e-09 36.1 0.0 2.0 1 1 0 1 1 1 1 MutS domain II RTC_insert PF05189.8 EMR61567.1 - 2.3e-28 98.2 0.8 4.9e-28 97.1 0.1 1.9 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 EMR61567.1 - 3e-28 98.1 0.1 4.2e-28 97.6 0.1 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Mem_trans PF03547.13 EMR61568.1 - 2.7e-27 95.0 0.1 3.7e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Membrane transport protein Nop14 PF04147.7 EMR61568.1 - 0.044 11.7 0.6 0.051 11.4 0.4 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EMR61568.1 - 0.38 8.7 3.2 0.52 8.2 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.1 EMR61568.1 - 1.3 8.1 5.4 1.8 7.7 3.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4175 PF13779.1 EMR61568.1 - 6.4 4.3 15.4 11 3.6 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PWWP PF00855.12 EMR61570.1 - 2e-10 40.7 0.0 2e-10 40.7 0.0 2.9 3 0 0 3 3 3 1 PWWP domain DUF2217 PF10265.4 EMR61570.1 - 3.3 6.3 9.7 5.1 5.7 6.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) CPSase_L_D2 PF02786.12 EMR61571.1 - 9e-110 364.9 0.0 2.9e-84 281.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EMR61571.1 - 7.8e-40 135.4 0.0 1.8e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EMR61571.1 - 7.1e-39 133.4 0.2 3.1e-21 75.9 0.0 2.6 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 EMR61571.1 - 7e-36 122.6 0.0 6.2e-17 61.6 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EMR61571.1 - 1.2e-24 86.7 0.0 1.5e-08 33.7 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EMR61571.1 - 3.6e-19 68.7 0.0 3.2e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMR61571.1 - 9.6e-17 61.0 0.2 2.5e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EMR61571.1 - 1.3e-07 31.2 0.0 0.00075 19.0 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EMR61571.1 - 2.7e-05 24.0 0.1 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 EMR61571.1 - 3.6e-05 23.4 1.3 0.12 11.9 0.1 2.7 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 EMR61571.1 - 0.00049 19.3 0.0 0.44 9.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain DUF1614 PF07758.6 EMR61571.1 - 0.096 12.4 1.0 17 5.1 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1614) BEX PF04538.7 EMR61572.1 - 0.03 14.5 0.1 0.032 14.4 0.1 1.1 1 0 0 1 1 1 0 Brain expressed X-linked like family NPL4 PF05021.10 EMR61574.1 - 5.3e-127 423.1 0.0 6.7e-127 422.8 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EMR61574.1 - 6.1e-69 230.3 0.1 1e-68 229.6 0.1 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EMR61574.1 - 3.7e-05 23.9 0.0 7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Sec63 PF02889.11 EMR61575.1 - 6.2e-193 639.9 0.3 4.2e-107 358.0 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EMR61575.1 - 2.9e-54 183.0 1.0 1.4e-31 109.3 0.1 4.2 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 EMR61575.1 - 1e-17 64.5 0.0 4.3e-09 36.4 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMR61575.1 - 3.9e-12 45.8 0.0 2.7e-09 36.7 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EMR61575.1 - 5.6e-07 29.7 0.1 0.0047 17.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 EMR61575.1 - 0.00063 19.0 0.0 0.17 11.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_10 PF12846.2 EMR61575.1 - 0.0015 18.0 0.0 3.6 6.9 0.0 3.6 4 0 0 4 4 4 2 AAA-like domain AAA_19 PF13245.1 EMR61575.1 - 0.039 13.7 0.0 7.2 6.4 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 EMR61575.1 - 0.041 14.2 0.3 17 5.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain HET PF06985.6 EMR61576.1 - 2.8e-19 69.6 6.8 2.5e-17 63.3 0.8 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TLD PF07534.11 EMR61577.1 - 1.8e-26 92.7 0.0 7.2e-26 90.8 0.0 2.0 1 1 0 1 1 1 1 TLD MUG2_C PF08593.5 EMR61577.1 - 1.4e-13 50.8 0.1 3.1e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal Rhodanese PF00581.15 EMR61578.1 - 1.3e-25 89.9 0.0 6.5e-15 55.4 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Ribosomal_S5 PF00333.15 EMR61579.1 - 6.9e-28 96.1 2.1 1.5e-27 95.1 1.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EMR61579.1 - 1e-18 66.3 0.0 2.6e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain WSC PF01822.14 EMR61579.1 - 5.4e-10 39.0 0.6 9.9e-10 38.2 0.4 1.4 1 0 0 1 1 1 1 WSC domain HIG_1_N PF04588.8 EMR61581.1 - 3.3e-21 74.7 0.9 7e-21 73.7 0.6 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF1860 PF08949.5 EMR61581.1 - 0.045 13.3 2.2 0.064 12.8 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) EIF_2_alpha PF07541.7 EMR61581.1 - 0.088 12.5 0.2 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Tannase PF07519.6 EMR61582.1 - 3.2e-89 299.8 0.0 6.9e-89 298.7 0.0 1.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase Pec_lyase_C PF00544.14 EMR61583.1 - 3.5e-20 72.3 5.0 8e-20 71.1 3.4 1.5 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EMR61583.1 - 8.3e-06 25.6 11.4 0.00065 19.4 7.7 2.5 1 1 0 1 1 1 1 Right handed beta helix region Acetyltransf_1 PF00583.19 EMR61584.1 - 5.3e-13 48.8 0.0 8.2e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR61584.1 - 7.9e-08 32.3 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR61584.1 - 1.3e-05 25.2 0.0 1.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR61584.1 - 0.0016 18.1 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EMR61584.1 - 0.0021 18.2 0.0 0.0028 17.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMR61584.1 - 0.0029 17.5 0.0 0.004 17.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HET PF06985.6 EMR61585.1 - 7.3e-32 110.4 0.3 7.3e-32 110.4 0.2 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) SDA1 PF05285.7 EMR61585.1 - 0.005 16.1 9.7 0.0083 15.4 6.7 1.4 1 0 0 1 1 1 1 SDA1 Paf1 PF03985.8 EMR61585.1 - 0.016 13.9 6.5 0.024 13.3 4.5 1.1 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.7 EMR61585.1 - 0.19 9.5 21.6 0.33 8.8 15.0 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EMR61585.1 - 0.45 8.4 15.2 0.82 7.6 10.5 1.3 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 EMR61585.1 - 1.3 7.1 9.3 2 6.5 6.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Daxx PF03344.10 EMR61585.1 - 3.3 6.0 21.7 6.2 5.1 15.0 1.3 1 0 0 1 1 1 0 Daxx Family ADH_N PF08240.7 EMR61586.1 - 3.9e-11 42.6 0.0 7.1e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR61586.1 - 5.6e-05 22.6 0.5 0.00011 21.8 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase VWA PF00092.23 EMR61586.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain NmrA PF05368.8 EMR61586.1 - 0.042 13.0 0.1 0.068 12.4 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Fungal_lectin PF07938.7 EMR61587.1 - 0.00019 20.8 1.1 0.011 15.0 0.1 2.9 2 1 1 3 3 3 1 Fungal fucose-specific lectin Caldesmon PF02029.10 EMR61587.1 - 0.058 11.8 19.0 0.082 11.3 13.2 1.1 1 0 0 1 1 1 0 Caldesmon Chon_Sulph_att PF06566.6 EMR61587.1 - 0.069 12.7 1.9 2.6 7.6 0.4 2.5 2 1 1 3 3 3 0 Chondroitin sulphate attachment domain DDHD PF02862.12 EMR61587.1 - 0.25 11.0 3.8 0.4 10.4 2.6 1.2 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 EMR61587.1 - 1 6.9 5.0 1.3 6.6 3.5 1.1 1 0 0 1 1 1 0 Ycf1 U79_P34 PF03064.11 EMR61587.1 - 1.8 8.0 11.6 2.8 7.3 8.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DNA_pol3_a_NII PF11490.3 EMR61587.1 - 8.6 6.0 11.4 14 5.2 7.9 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II PcfK PF14058.1 EMR61587.1 - 8.8 6.4 10.0 16 5.6 6.9 1.3 1 0 0 1 1 1 0 PcfK-like protein PALP PF00291.20 EMR61588.1 - 4.9e-72 242.7 0.5 6.2e-72 242.4 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EMR61588.1 - 1.1e-37 127.4 0.0 2e-20 72.1 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Epimerase PF01370.16 EMR61589.1 - 7.3e-18 64.8 0.0 1.2e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR61589.1 - 4.6e-13 48.4 0.0 8.8e-13 47.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMR61589.1 - 1e-11 45.1 0.3 2.1e-10 40.9 0.3 2.4 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMR61589.1 - 5.8e-11 41.7 0.0 8.3e-10 38.0 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EMR61589.1 - 1.8e-07 31.2 0.1 3.8e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EMR61589.1 - 9.1e-07 28.3 0.1 0.00079 18.7 0.1 2.9 2 1 0 2 2 2 2 NmrA-like family KR PF08659.5 EMR61589.1 - 7.3e-05 22.5 0.1 0.00013 21.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMR61589.1 - 0.00051 19.0 0.0 0.0012 17.7 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EMR61589.1 - 0.00088 19.6 0.2 0.0055 17.1 0.0 2.2 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 EMR61589.1 - 0.041 12.7 0.0 0.091 11.6 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain Bac_luciferase PF00296.15 EMR61590.1 - 8.9e-24 84.1 0.0 1.1e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1443 PF07280.6 EMR61591.1 - 4.6 6.8 9.9 3.9 7.1 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1443) EHN PF06441.7 EMR61592.1 - 5.1e-27 94.0 0.0 9.2e-27 93.1 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EMR61592.1 - 8.3e-08 32.3 7.2 1.6e-07 31.4 5.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR61592.1 - 4.8e-06 26.3 0.3 1.1e-05 25.1 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold MFS_1 PF07690.11 EMR61593.1 - 2.2e-32 112.1 29.4 2.9e-32 111.7 20.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SAC3_GANP PF03399.11 EMR61594.1 - 0.013 15.0 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF892 PF05974.7 EMR61594.1 - 0.048 13.4 0.1 0.073 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF892) TPR_19 PF14559.1 EMR61595.1 - 0.0012 19.1 1.2 0.73 10.2 0.0 3.2 3 1 1 4 4 4 2 Tetratricopeptide repeat Pyr_redox_3 PF13738.1 EMR61596.1 - 1.2e-16 61.3 0.0 8.6e-16 58.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR61596.1 - 3.8e-05 22.7 0.1 0.00047 19.1 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EMR61596.1 - 4e-05 22.0 0.0 0.0015 16.8 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like PHZA_PHZB PF03284.8 EMR61596.1 - 0.071 12.1 0.2 0.25 10.3 0.0 1.9 2 0 0 2 2 2 0 Phenazine biosynthesis protein A/B Abhydrolase_6 PF12697.2 EMR61597.1 - 2.5e-13 50.4 0.0 3.4e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR61597.1 - 0.0051 16.5 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR61597.1 - 0.073 12.6 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold LtrA PF06772.6 EMR61599.1 - 0.21 10.4 20.8 0.014 14.3 6.1 2.9 2 1 1 3 3 3 0 Bacterial low temperature requirement A protein (LtrA) adh_short_C2 PF13561.1 EMR61600.1 - 1.7e-27 96.7 1.9 2e-27 96.4 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR61600.1 - 3.2e-23 82.4 4.1 3.2e-23 82.4 2.9 1.7 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR61600.1 - 4.9e-10 39.3 5.5 1.4e-08 34.6 0.3 2.6 3 0 0 3 3 3 2 KR domain Epimerase PF01370.16 EMR61600.1 - 5.8e-05 22.6 0.2 7.9e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMR61600.1 - 0.0044 15.9 0.1 0.0069 15.3 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Fibrillarin PF01269.12 EMR61600.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Ldh_1_N PF00056.18 EMR61600.1 - 0.29 10.9 2.9 0.26 11.1 0.2 2.0 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EMR61600.1 - 1.6 8.5 6.1 0.14 11.9 0.5 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glycos_transf_2 PF00535.21 EMR61601.1 - 3.9e-33 114.5 0.0 4.7e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMR61601.1 - 1.8e-11 44.2 0.0 3.2e-11 43.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EMR61601.1 - 4.3e-09 35.8 0.0 5.7e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EMR61601.1 - 3.9e-05 22.9 0.0 6.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Amidoligase_2 PF12224.3 EMR61602.1 - 3.5e-12 46.4 0.0 2.3e-08 33.9 0.0 2.7 3 0 0 3 3 3 2 Putative amidoligase enzyme ADH_N PF08240.7 EMR61603.1 - 1.2e-16 60.3 0.1 4e-16 58.7 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR61603.1 - 8.1e-09 35.1 0.1 8.1e-08 31.8 0.1 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EMR61603.1 - 0.13 10.7 0.1 0.24 9.8 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Abhydrolase_3 PF07859.8 EMR61604.1 - 2e-42 145.2 0.1 2.5e-42 144.8 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR61604.1 - 0.00017 21.3 0.2 0.00027 20.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR61604.1 - 0.00061 19.0 0.0 0.081 12.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 EMR61604.1 - 0.009 14.7 0.6 0.021 13.5 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family DLH PF01738.13 EMR61604.1 - 0.012 14.8 0.1 0.074 12.3 0.0 2.2 3 0 0 3 3 3 0 Dienelactone hydrolase family FSH1 PF03959.8 EMR61604.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_M18 PF02127.10 EMR61605.1 - 7.4e-164 545.3 0.0 4.6e-163 542.7 0.0 1.8 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EMR61605.1 - 5.6e-06 25.3 0.3 0.00026 19.8 0.0 2.8 2 1 0 3 3 3 1 M42 glutamyl aminopeptidase Xpo1 PF08389.7 EMR61606.1 - 2.9e-32 111.6 0.5 6.3e-31 107.2 0.0 3.3 3 1 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 EMR61606.1 - 0.0013 18.6 0.6 19 5.6 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat NTF2 PF02136.15 EMR61608.1 - 3.9e-23 82.0 0.8 7.3e-23 81.1 0.5 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EMR61608.1 - 1.3e-06 27.9 0.1 2.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR61608.1 - 0.00065 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMR61608.1 - 0.0033 17.2 0.3 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.1 EMR61608.1 - 0.0085 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sushi_2 PF09014.5 EMR61608.1 - 0.02 14.6 0.1 0.04 13.6 0.1 1.4 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain PAT1 PF09770.4 EMR61608.1 - 5.8 5.0 20.4 7.4 4.6 14.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_hydro_10 PF00331.15 EMR61609.1 - 6.8e-95 317.7 0.0 8.1e-95 317.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.10 EMR61609.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase Pneumo_att_G PF05539.6 EMR61609.1 - 1.2 8.4 17.7 1.6 7.9 12.3 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Mucin PF01456.12 EMR61609.1 - 1.3 8.7 34.5 3 7.6 23.9 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.3 EMR61609.1 - 3.6 6.7 21.6 5.2 6.1 15.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Alpha_GJ PF03229.8 EMR61609.1 - 3.8 7.8 19.8 13 6.1 13.8 2.0 1 0 0 1 1 1 0 Alphavirus glycoprotein J Nipped-B_C PF12830.2 EMR61610.1 - 2.5e-44 151.1 1.5 7.2e-44 149.6 0.4 2.4 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EMR61610.1 - 2.9e-12 46.2 4.2 7.5e-11 41.7 0.3 3.5 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EMR61610.1 - 1.1e-05 25.0 0.1 0.021 14.8 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat Adaptin_N PF01602.15 EMR61610.1 - 0.0015 16.9 4.6 0.0017 16.7 0.2 3.1 3 0 0 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.2 EMR61610.1 - 0.0029 17.4 0.2 0.21 11.4 0.0 3.6 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EMR61611.1 - 1.2e-27 95.9 6.4 2.2e-13 50.2 0.0 3.5 2 2 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 EMR61611.1 - 2.1e-17 61.7 7.7 0.027 14.9 0.0 6.7 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EMR61611.1 - 2.6e-06 27.7 10.9 0.067 13.7 0.6 4.8 2 2 2 4 4 4 3 HEAT-like repeat HEAT PF02985.17 EMR61611.1 - 5.9e-05 22.8 6.6 2.2 8.6 0.0 5.8 7 0 0 7 7 7 3 HEAT repeat DUF3632 PF12311.3 EMR61612.1 - 1.6e-23 83.4 0.0 2.1e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) PNPOx_C PF10590.4 EMR61613.1 - 8.5e-21 73.1 0.3 8.5e-21 73.1 0.2 2.3 3 0 0 3 3 3 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EMR61613.1 - 1.7e-18 66.3 0.0 2.8e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EMR61613.1 - 0.0083 16.4 0.0 0.021 15.1 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Collagen PF01391.13 EMR61614.1 - 0.00094 18.6 12.0 0.00094 18.6 8.3 2.0 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) TFIIS_C PF01096.13 EMR61616.1 - 2.1e-14 52.8 1.5 2.1e-14 52.8 1.1 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EMR61616.1 - 2.3e-05 23.9 4.2 2.3e-05 23.9 2.9 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.1 EMR61616.1 - 0.039 13.4 15.4 0.91 9.0 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.2 EMR61616.1 - 0.047 13.5 7.6 0.13 12.1 0.8 2.6 3 0 0 3 3 3 0 Double zinc ribbon C1_1 PF00130.17 EMR61616.1 - 0.17 11.6 5.9 0.11 12.1 0.8 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 EMR61616.1 - 0.58 9.8 9.4 1.5 8.5 0.7 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Lar_restr_allev PF14354.1 EMR61616.1 - 1.2 9.5 10.0 3 8.2 0.2 3.1 2 1 0 2 2 2 0 Restriction alleviation protein Lar Zn_ribbon_recom PF13408.1 EMR61616.1 - 2.1 8.6 12.2 2.7 8.3 0.0 3.2 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain zf-CHY PF05495.7 EMR61616.1 - 2.3 8.4 8.5 3.8 7.7 0.6 2.3 2 1 0 2 2 2 0 CHY zinc finger HypA PF01155.14 EMR61616.1 - 2.4 7.8 8.9 1.1 8.9 0.6 2.4 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-trcl PF13451.1 EMR61616.1 - 3.4 7.3 8.1 8.4 6.1 0.1 3.2 3 0 0 3 3 3 0 Probable zinc-binding domain IBR PF01485.16 EMR61616.1 - 7.8 6.4 11.2 0.85 9.5 0.8 2.7 2 1 0 2 2 2 0 IBR domain CorA PF01544.13 EMR61618.1 - 3.4e-11 42.7 0.1 4.6e-11 42.2 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4231 PF14015.1 EMR61618.1 - 0.2 11.6 1.5 0.26 11.2 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) IBR PF01485.16 EMR61619.1 - 5.2e-08 32.6 16.1 5.9e-06 26.0 4.0 4.3 4 1 0 4 4 4 2 IBR domain Transferase PF02458.10 EMR61620.1 - 1.5e-08 33.5 0.0 2.9e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 Transferase family DUF2611 PF11022.3 EMR61621.1 - 1.3e-29 102.1 0.2 1.3e-29 102.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) UCR_TM PF02921.9 EMR61623.1 - 2.9e-17 62.6 0.2 2.9e-17 62.6 0.2 1.9 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EMR61623.1 - 1.3e-16 59.9 0.1 3.3e-16 58.6 0.1 1.6 1 1 1 2 2 2 1 Rieske [2Fe-2S] domain adh_short PF00106.20 EMR61624.1 - 1.4e-20 73.9 0.0 2.3e-20 73.1 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR61624.1 - 3.4e-10 39.8 0.0 4.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR61624.1 - 0.00086 18.8 0.0 0.0019 17.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EMR61624.1 - 0.023 13.6 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase MTP18 PF10558.4 EMR61626.1 - 4.7e-69 231.0 0.1 6e-69 230.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Cpn60_TCP1 PF00118.19 EMR61629.1 - 9.5e-143 476.3 12.0 1.1e-142 476.1 8.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GspL_C PF12693.2 EMR61629.1 - 0.076 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 GspL periplasmic domain Phage_int_SAM_1 PF02899.12 EMR61629.1 - 0.11 12.6 0.0 0.57 10.3 0.0 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain zf-MYND PF01753.13 EMR61630.1 - 3.8e-09 36.2 16.3 7e-09 35.4 11.3 1.4 1 0 0 1 1 1 1 MYND finger VGLL4 PF15245.1 EMR61630.1 - 0.018 14.9 0.1 0.026 14.3 0.1 1.2 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 FAA_hydrolase PF01557.13 EMR61632.1 - 4e-52 176.8 0.0 7e-52 176.0 0.0 1.4 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family DUF1722 PF08349.6 EMR61632.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) RhoGEF PF00621.15 EMR61633.1 - 1.9e-15 57.2 1.0 4.1e-07 30.0 0.0 2.5 1 1 1 2 2 2 2 RhoGEF domain DUF3507 PF12015.3 EMR61633.1 - 0.00032 20.2 0.0 0.00066 19.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Aldolase_II PF00596.16 EMR61634.1 - 3.3e-46 157.2 0.2 4.3e-46 156.8 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Acetyltransf_7 PF13508.1 EMR61635.1 - 0.0033 17.5 0.0 0.0083 16.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR61635.1 - 0.0077 16.0 0.0 0.024 14.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR61635.1 - 0.042 13.8 0.2 0.3 11.1 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family NeA_P2 PF12312.3 EMR61635.1 - 0.18 11.0 2.7 0.63 9.2 0.7 2.1 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein CAP_N PF01213.14 EMR61635.1 - 1.8 7.8 8.2 11 5.1 3.4 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EMR61635.1 - 3.8 6.8 12.1 0.44 9.8 2.9 2.5 2 1 0 2 2 2 0 Mitochondrial fission regulator MMS1_N PF10433.4 EMR61636.1 - 7.2e-86 288.3 0.0 1e-85 287.8 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EMR61636.1 - 1.8e-62 211.3 0.0 7e-62 209.3 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region zf-AN1 PF01428.11 EMR61638.1 - 1.6e-23 82.3 19.2 3.2e-12 46.1 4.6 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EMR61638.1 - 0.0016 18.6 15.0 0.098 12.8 1.2 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain IBR PF01485.16 EMR61638.1 - 0.0058 16.4 12.9 0.043 13.6 1.4 2.5 2 0 0 2 2 2 2 IBR domain Rad4 PF03835.10 EMR61639.1 - 1.3e-33 115.4 0.4 1.3e-33 115.4 0.3 2.3 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EMR61639.1 - 5.6e-28 96.4 0.2 1.1e-27 95.5 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EMR61639.1 - 1.5e-18 66.0 0.3 3.9e-18 64.7 0.2 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EMR61639.1 - 5e-14 52.3 0.1 5e-14 52.3 0.1 3.4 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 MatE PF01554.13 EMR61640.1 - 0.04 13.5 0.4 0.061 12.9 0.3 1.3 1 0 0 1 1 1 0 MatE DnaJ PF00226.26 EMR61641.1 - 6.4e-13 48.2 0.4 6.4e-13 48.2 0.3 2.5 3 0 0 3 3 3 1 DnaJ domain DUF202 PF02656.10 EMR61642.1 - 4.4e-20 71.6 3.1 1.3e-19 70.1 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Calcyon PF06387.6 EMR61642.1 - 0.023 14.0 0.3 0.034 13.5 0.2 1.3 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) Tic20 PF09685.5 EMR61642.1 - 0.092 12.7 5.6 2.7 7.9 3.7 2.2 1 1 0 1 1 1 0 Tic20-like protein Tetraspannin PF00335.15 EMR61642.1 - 0.76 9.0 5.1 0.49 9.6 2.0 1.8 2 0 0 2 2 2 0 Tetraspanin family COX4_pro_2 PF07835.7 EMR61642.1 - 0.97 9.4 3.6 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV Daxx PF03344.10 EMR61644.1 - 2.7 6.3 14.9 4.9 5.5 10.3 1.3 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EMR61644.1 - 5.9 4.7 11.6 11 3.8 8.0 1.4 1 0 0 1 1 1 0 CDC45-like protein DEAD PF00270.24 EMR61645.1 - 7.3e-46 155.7 0.1 4.2e-45 153.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR61645.1 - 2.3e-16 59.4 0.0 1.5e-15 56.7 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR61645.1 - 9e-05 22.3 0.0 0.00024 21.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMR61645.1 - 9.1e-05 21.3 0.0 0.00017 20.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain BUD22 PF09073.5 EMR61645.1 - 0.094 11.7 11.4 0.17 10.8 7.9 1.3 1 0 0 1 1 1 0 BUD22 DUF1014 PF06244.7 EMR61646.1 - 8.7e-23 80.8 14.8 4.5e-22 78.5 10.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) DUF4551 PF15087.1 EMR61646.1 - 7.2 4.8 9.2 9.4 4.4 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Mito_carr PF00153.22 EMR61647.1 - 2.4e-32 110.5 0.2 4.5e-20 71.1 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein RdRP_2 PF00978.16 EMR61648.1 - 2.6e-72 243.9 0.0 4e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Vmethyltransf PF01660.12 EMR61648.1 - 1.3e-38 132.5 0.4 2e-38 131.8 0.3 1.2 1 0 0 1 1 1 1 Viral methyltransferase Viral_helicase1 PF01443.13 EMR61648.1 - 6.7e-30 104.3 0.0 1.5e-29 103.2 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase OTT_1508_deam PF14441.1 EMR61650.1 - 2.1e-06 27.5 0.0 4.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase zf-MYND PF01753.13 EMR61650.1 - 1e-05 25.2 9.9 3.5e-05 23.5 6.9 2.0 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EMR61650.1 - 0.00026 20.7 4.7 0.00046 19.9 2.3 2.3 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.11 EMR61650.1 - 0.17 11.5 12.0 0.025 14.2 5.2 2.0 2 0 0 2 2 2 0 HIT zinc finger DEAD PF00270.24 EMR61651.1 - 8.6e-14 51.3 0.0 3.7e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 EMR61651.1 - 0.0012 17.8 0.0 0.013 14.4 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 EMR61651.1 - 0.0015 18.2 0.1 0.0069 16.1 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EMR61651.1 - 0.0033 17.5 0.0 0.0088 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EMR61651.1 - 0.0046 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 EMR61651.1 - 0.011 15.6 0.5 0.045 13.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EMR61651.1 - 0.079 12.5 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynactin_p62 PF05502.8 EMR61652.1 - 1.6e-141 472.4 0.0 2e-141 472.0 0.0 1.2 1 0 0 1 1 1 1 Dynactin p62 family CD99L2 PF12301.3 EMR61652.1 - 0.22 11.1 0.1 0.22 11.1 0.0 3.3 4 0 0 4 4 4 0 CD99 antigen like protein 2 Ribosomal_S7e PF01251.13 EMR61653.1 - 1.8e-81 272.2 0.6 2e-81 272.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e EBP PF05241.7 EMR61654.1 - 1.6e-05 23.9 4.0 2.2e-05 23.5 2.6 1.6 1 1 0 1 1 1 1 Emopamil binding protein MIF4G_like PF09088.6 EMR61657.1 - 2.1e-79 265.4 0.0 3.3e-79 264.7 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EMR61657.1 - 1.1e-51 175.5 0.0 1.7e-51 174.9 0.0 1.3 1 0 0 1 1 1 1 MIF4G like WD40 PF00400.27 EMR61657.1 - 5.5e-40 133.8 12.8 3.9e-07 29.7 0.0 10.8 11 0 0 11 11 11 7 WD domain, G-beta repeat OMP_b-brl PF13505.1 EMR61657.1 - 0.091 12.6 4.1 0.12 12.2 1.6 2.0 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain MIF4G PF02854.14 EMR61657.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 MIF4G domain Fes1 PF08609.5 EMR61658.1 - 1.3e-29 102.4 1.2 1.3e-29 102.4 0.9 2.4 3 1 0 3 3 3 1 Nucleotide exchange factor Fes1 HEAT PF02985.17 EMR61658.1 - 5.2e-05 22.9 1.0 0.059 13.4 0.1 3.6 3 1 0 3 3 3 1 HEAT repeat Arm PF00514.18 EMR61658.1 - 0.0008 19.1 1.8 0.22 11.4 0.1 3.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EMR61658.1 - 0.0011 19.4 2.1 0.31 11.5 0.2 3.1 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.1 EMR61658.1 - 0.0026 18.0 2.1 2.6 8.3 0.0 3.2 2 1 0 2 2 2 2 HEAT repeats UCH_1 PF13423.1 EMR61659.1 - 1.2e-28 100.4 1.8 2.3e-27 96.2 1.2 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Methyltransf_2 PF00891.13 EMR61660.1 - 6.2e-31 107.4 0.0 9.8e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase DUF1774 PF08611.5 EMR61661.1 - 1.8 8.7 6.7 2.4 8.3 2.8 2.3 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) WSC PF01822.14 EMR61662.1 - 2.3e-36 123.5 28.4 2.1e-19 69.1 7.2 2.5 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.18 EMR61662.1 - 4.2e-17 62.3 0.0 8.9e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Peroxidase Porin_3 PF01459.17 EMR61663.1 - 1.1e-76 257.7 0.0 1.3e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin PagL PF09411.5 EMR61663.1 - 0.02 14.9 0.1 0.71 9.9 0.0 2.7 2 1 1 3 3 3 0 Lipid A 3-O-deacylase (PagL) RF-1 PF00472.15 EMR61664.1 - 1.9e-25 88.8 0.2 2.9e-25 88.2 0.2 1.2 1 0 0 1 1 1 1 RF-1 domain PDZ_1 PF12812.2 EMR61665.1 - 2.1e-14 53.1 0.0 8.6e-07 28.7 0.0 3.6 3 0 0 3 3 3 2 PDZ-like domain PDZ_2 PF13180.1 EMR61665.1 - 4.8e-14 52.0 0.7 9.6e-08 31.8 0.0 3.8 3 0 0 3 3 3 2 PDZ domain Trypsin_2 PF13365.1 EMR61665.1 - 4.9e-13 49.1 0.1 1.5e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 EMR61665.1 - 1.8e-08 34.3 0.0 9.6e-05 22.4 0.0 3.4 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Peptidase_S7 PF00949.16 EMR61665.1 - 0.0015 17.9 0.4 0.0035 16.7 0.3 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Trypsin PF00089.21 EMR61665.1 - 0.0028 17.2 0.0 0.016 14.8 0.0 2.2 2 1 0 2 2 2 1 Trypsin Peptidase_S46 PF10459.4 EMR61665.1 - 0.022 13.1 0.1 0.043 12.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase S46 DUF31 PF01732.11 EMR61665.1 - 0.04 13.2 0.1 0.094 12.0 0.0 1.6 2 0 0 2 2 2 0 Putative peptidase (DUF31) Tricorn_PDZ PF14685.1 EMR61665.1 - 0.042 13.6 0.2 0.54 10.0 0.0 2.7 2 0 0 2 2 2 0 Tricorn protease PDZ domain SPC22 PF04573.7 EMR61666.1 - 2.2e-33 114.9 0.9 5.9e-24 84.2 0.1 2.0 2 0 0 2 2 2 2 Signal peptidase subunit Actin PF00022.14 EMR61667.1 - 5.6e-159 528.7 0.0 6.3e-159 528.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EMR61667.1 - 0.039 14.3 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pkinase PF00069.20 EMR61668.1 - 1.9e-59 200.9 0.0 1.2e-58 198.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR61668.1 - 1.2e-22 80.2 0.1 9e-22 77.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR61668.1 - 1.5e-07 30.6 0.0 3.6e-07 29.4 0.0 1.5 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EMR61668.1 - 0.00016 21.4 0.3 0.0038 16.9 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMR61668.1 - 0.017 14.6 0.1 0.066 12.7 0.0 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 EMR61668.1 - 0.062 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Asp_protease_2 PF13650.1 EMR61669.1 - 0.037 14.5 0.0 0.072 13.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease 6PF2K PF01591.13 EMR61670.1 - 4.6e-48 163.2 0.1 1.8e-47 161.3 0.0 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EMR61670.1 - 1e-21 77.7 0.5 1.6e-21 77.0 0.3 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EMR61670.1 - 0.033 14.0 1.2 2.7 7.8 0.0 2.9 2 2 0 2 2 2 0 AAA domain DUF3317 PF11779.3 EMR61671.1 - 4.4e-19 67.6 3.7 5.5e-19 67.3 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Acetyltransf_1 PF00583.19 EMR61672.1 - 4.9e-05 23.2 0.0 0.00013 21.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR61672.1 - 7.5e-05 22.8 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR61672.1 - 0.00048 19.9 0.1 0.0014 18.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR61672.1 - 0.0053 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF336 PF03928.9 EMR61673.1 - 6e-20 71.3 0.0 7.8e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Peptidase_C48 PF02902.14 EMR61674.1 - 7.1e-26 91.1 0.0 1.9e-25 89.7 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain NADH-u_ox-rdase PF10785.4 EMR61675.1 - 0.13 12.5 1.0 0.2 11.9 0.7 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NmrA PF05368.8 EMR61676.1 - 1.5e-14 53.7 0.0 2.1e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR61676.1 - 9.1e-09 35.5 0.1 1e-08 35.4 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EMR61676.1 - 0.0022 18.0 0.0 0.0028 17.7 0.0 1.1 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GARS_N PF02844.10 EMR61676.1 - 0.04 14.3 0.0 0.071 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain E1-E2_ATPase PF00122.15 EMR61677.1 - 1.2e-57 194.5 1.7 3.4e-57 193.1 1.2 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMR61677.1 - 3.6e-47 160.2 3.0 1.5e-46 158.2 0.3 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMR61677.1 - 1.2e-25 91.2 0.1 1.2e-24 87.9 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMR61677.1 - 1.6e-19 69.6 0.0 3.7e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMR61677.1 - 1.1e-14 55.1 0.0 1.8e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMR61677.1 - 2.5e-06 26.8 0.1 2e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMR61677.1 - 3.3e-06 26.8 0.4 7.6e-06 25.6 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L5_C PF00673.16 EMR61678.1 - 1e-15 57.2 0.0 2.1e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EMR61678.1 - 4.6e-06 26.3 0.0 9.8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 ketoacyl-synt PF00109.21 EMR61679.1 - 2.5e-71 240.1 0.0 4.8e-71 239.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMR61679.1 - 1.8e-56 191.7 0.0 2.9e-56 191.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EMR61679.1 - 3.3e-53 180.0 0.1 1.2e-52 178.2 0.0 2.1 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EMR61679.1 - 1.2e-43 149.3 0.1 2.5e-43 148.3 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EMR61679.1 - 2.6e-41 141.3 0.7 1.5e-40 138.8 0.0 2.6 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EMR61679.1 - 1.7e-19 69.6 0.0 1.4e-18 66.7 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ketoacyl-synt_C PF02801.17 EMR61679.1 - 1.4e-16 60.3 0.0 3.1e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_23 PF13489.1 EMR61679.1 - 2.4e-15 56.6 0.0 6e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EMR61679.1 - 1.1e-14 55.4 0.0 1.1e-13 52.2 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMR61679.1 - 1.6e-14 54.1 0.0 4.6e-14 52.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR61679.1 - 1.6e-09 37.5 0.0 3.2e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR61679.1 - 2.4e-09 37.3 0.1 4.2e-08 33.3 0.1 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EMR61679.1 - 5.4e-09 36.6 0.0 1.5e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR61679.1 - 7.2e-08 32.8 0.0 3.1e-07 30.7 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR61679.1 - 1.5e-05 24.2 0.1 3.7e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EMR61679.1 - 7.3e-05 22.2 0.0 0.00019 20.9 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EMR61679.1 - 0.00068 19.9 0.0 0.0021 18.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EMR61679.1 - 0.0043 16.8 0.0 0.0099 15.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EMR61679.1 - 0.0044 16.0 0.1 0.0079 15.2 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EMR61679.1 - 0.041 13.5 1.2 0.46 10.1 0.6 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PCMT PF01135.14 EMR61679.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RTX PF02382.10 EMR61679.1 - 0.54 8.4 0.0 0.96 7.6 0.0 1.3 1 0 0 1 1 1 0 RTX N-terminal domain HORMA PF02301.13 EMR61680.1 - 1.5e-23 83.3 0.0 1.9e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 HORMA domain MFS_1 PF07690.11 EMR61681.1 - 1.8e-53 181.4 30.2 2.2e-53 181.1 20.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR61681.1 - 2e-13 49.7 18.0 3.5e-13 48.9 12.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 EMR61681.1 - 0.054 11.6 11.7 0.0084 14.2 5.1 1.6 1 1 0 1 1 1 0 Transmembrane secretion effector Prefoldin_2 PF01920.15 EMR61682.1 - 1.5e-26 92.2 3.4 1.7e-26 92.0 2.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin-6_N PF09177.6 EMR61682.1 - 0.0011 19.2 2.9 0.26 11.7 0.5 2.1 1 1 1 2 2 2 2 Syntaxin 6, N-terminal IncA PF04156.9 EMR61682.1 - 0.0026 17.3 3.8 0.0032 17.1 2.6 1.1 1 0 0 1 1 1 1 IncA protein DUF915 PF06028.6 EMR61682.1 - 0.0094 15.0 0.5 0.017 14.1 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) V_ATPase_I PF01496.14 EMR61682.1 - 0.01 13.7 1.3 0.012 13.5 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FTA4 PF13093.1 EMR61682.1 - 0.017 14.5 2.1 0.02 14.3 1.4 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4200 PF13863.1 EMR61682.1 - 0.021 14.7 2.3 0.031 14.2 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FliJ PF02050.11 EMR61682.1 - 0.028 14.4 3.7 0.47 10.5 0.6 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Tho2 PF11262.3 EMR61682.1 - 0.028 13.4 3.5 0.91 8.5 2.5 2.0 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF2205 PF10224.4 EMR61682.1 - 0.046 13.3 3.9 0.14 11.7 0.5 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Prefoldin PF02996.12 EMR61682.1 - 0.054 13.1 6.6 1.1 8.9 0.1 2.3 1 1 2 3 3 3 0 Prefoldin subunit MAD PF05557.8 EMR61682.1 - 0.086 10.9 4.7 0.11 10.5 3.3 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF512 PF04459.7 EMR61682.1 - 0.1 11.6 0.2 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Phage_Mu_Gam PF07352.7 EMR61682.1 - 0.15 11.5 2.9 0.2 11.2 2.0 1.1 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein p25-alpha PF05517.7 EMR61682.1 - 0.15 12.2 2.2 0.51 10.5 0.3 2.0 1 1 0 2 2 2 0 p25-alpha GvpK PF05121.7 EMR61682.1 - 0.18 11.6 2.5 0.47 10.2 0.2 2.0 1 1 1 2 2 2 0 Gas vesicle protein K STAT_alpha PF01017.15 EMR61682.1 - 0.19 11.4 6.4 0.28 10.8 4.4 1.2 1 1 0 1 1 1 0 STAT protein, all-alpha domain Cytochrom_B562 PF07361.6 EMR61682.1 - 0.2 12.0 3.1 1.2 9.5 0.5 2.1 2 0 0 2 2 2 0 Cytochrome b562 Mnd1 PF03962.10 EMR61682.1 - 0.33 10.5 4.8 0.74 9.4 3.3 1.5 1 1 0 1 1 1 0 Mnd1 family DUF641 PF04859.7 EMR61682.1 - 0.49 10.1 4.0 1 9.0 0.3 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.3 EMR61682.1 - 0.68 9.7 9.5 0.13 12.0 2.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GAS PF13851.1 EMR61682.1 - 0.73 8.9 7.4 1.4 8.0 5.2 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DASH_Dad3 PF08656.5 EMR61682.1 - 0.78 9.4 4.9 0.43 10.3 1.5 1.8 2 0 0 2 2 2 0 DASH complex subunit Dad3 Seryl_tRNA_N PF02403.17 EMR61682.1 - 1.4 9.0 5.1 2.3 8.3 0.5 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc24 PF08286.6 EMR61682.1 - 2.7 7.6 6.8 9.3 5.9 4.7 1.9 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4351 PF14261.1 EMR61682.1 - 3 7.8 5.5 0.34 10.8 0.4 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4351) p450 PF00067.17 EMR61685.1 - 7.2e-39 133.5 0.7 9.4e-39 133.2 0.5 1.2 1 0 0 1 1 1 1 Cytochrome P450 FliH PF02108.11 EMR61685.1 - 0.011 15.6 1.2 3.5 7.5 0.2 3.2 2 1 1 3 3 3 0 Flagellar assembly protein FliH PCP_red PF08369.5 EMR61685.1 - 0.08 12.8 0.3 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Nop14 PF04147.7 EMR61686.1 - 0.019 12.9 14.9 0.018 12.9 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 EMR61686.1 - 0.041 13.7 16.3 0.05 13.5 11.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.4 EMR61686.1 - 0.19 10.3 21.3 0.3 9.7 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EMR61686.1 - 1.1 7.1 14.2 1.4 6.8 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 EMR61686.1 - 5.2 6.1 20.1 7.1 5.6 13.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Anoctamin PF04547.7 EMR61687.1 - 1.4e-118 396.4 8.1 1.8e-118 396.0 5.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel GRASP55_65 PF04495.9 EMR61688.1 - 2.9e-44 150.4 0.0 4e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Cmc1 PF08583.5 EMR61689.1 - 7.5e-18 64.0 3.6 8.7e-18 63.8 2.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like bZIP_1 PF00170.16 EMR61689.1 - 0.27 11.2 4.7 0.42 10.5 3.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 EMR61689.1 - 0.59 9.9 6.3 0.91 9.3 4.4 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Rho_GDI PF02115.12 EMR61690.1 - 3e-53 180.2 0.3 9.3e-53 178.6 0.1 1.8 2 0 0 2 2 2 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.23 EMR61691.1 - 4.2e-42 143.8 0.6 5.2e-42 143.5 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase p450 PF00067.17 EMR61692.1 - 1.5e-39 135.8 0.0 1.8e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Carn_acyltransf PF00755.15 EMR61693.1 - 2.9e-176 587.0 0.0 3.3e-176 586.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CBFD_NFYB_HMF PF00808.18 EMR61694.1 - 3.9e-29 100.5 0.9 5.2e-29 100.0 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMR61694.1 - 8.1e-07 29.0 0.1 1.3e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EMR61694.1 - 0.00094 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EMR61694.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EMR61694.1 - 0.026 14.7 0.1 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Mon1 PF03164.9 EMR61695.1 - 2.2e-116 388.9 0.0 2.6e-116 388.6 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 PPARgamma_N PF12577.3 EMR61695.1 - 0.03 14.6 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 PPAR gamma N-terminal region WSC PF01822.14 EMR61696.1 - 1.6e-11 43.9 3.2 1.6e-11 43.9 2.2 2.4 2 0 0 2 2 2 1 WSC domain Glyco_hydro_16 PF00722.16 EMR61696.1 - 0.00032 20.0 0.0 0.00061 19.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Tmemb_14 PF03647.8 EMR61697.1 - 2.4e-22 79.1 9.6 2.9e-22 78.8 6.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 EMR61697.1 - 0.0024 18.0 1.4 0.0049 17.0 1.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) DUF1427 PF07235.6 EMR61697.1 - 0.57 10.2 6.5 3 7.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) PfkB PF00294.19 EMR61698.1 - 3.8e-15 55.8 0.0 1.8e-09 37.2 0.3 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase KilA-N PF04383.8 EMR61699.1 - 0.0006 19.4 0.0 0.0093 15.5 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain TATR PF03430.8 EMR61699.1 - 1.6 7.2 7.8 2.1 6.8 5.4 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator IBN_N PF03810.14 EMR61700.1 - 1.3e-10 41.0 0.0 1.5e-09 37.5 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EMR61700.1 - 0.00036 20.4 0.1 0.55 10.1 0.0 4.2 5 0 0 5 5 5 2 Exportin 1-like protein Pyr_redox_3 PF13738.1 EMR61701.1 - 6e-16 59.1 0.0 1.5e-15 57.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR61701.1 - 4.1e-10 39.1 0.0 2.7e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EMR61701.1 - 6.2e-09 34.5 0.0 4.4e-08 31.7 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMR61701.1 - 1.8e-05 24.6 0.0 6.7e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR61701.1 - 0.00016 21.6 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR61701.1 - 0.018 14.1 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EMR61701.1 - 0.018 13.9 0.0 0.032 13.1 0.0 1.4 1 1 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.19 EMR61701.1 - 0.038 12.9 0.1 1.2 7.9 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thioredoxin PF00085.15 EMR61702.1 - 7.6e-65 215.1 6.8 5.7e-32 109.4 0.2 4.0 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EMR61702.1 - 3e-55 186.9 2.7 7.9e-41 139.8 0.6 3.5 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMR61702.1 - 1.9e-13 50.2 0.2 6.3e-07 29.3 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EMR61702.1 - 5.1e-12 45.7 0.1 0.00063 19.8 0.0 4.5 3 1 0 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.12 EMR61702.1 - 1.1e-10 40.8 2.3 1.6e-10 40.3 0.2 2.2 2 1 1 3 3 3 1 Calsequestrin Thioredoxin_2 PF13098.1 EMR61702.1 - 1.9e-10 40.9 5.2 0.00019 21.5 0.1 4.6 2 2 1 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EMR61702.1 - 5.8e-08 32.4 1.8 0.0019 17.8 0.2 3.3 2 1 1 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 EMR61702.1 - 2.6e-07 30.3 4.0 0.0081 15.7 0.0 3.7 3 1 0 3 3 3 2 Redoxin ERp29_N PF07912.8 EMR61702.1 - 8.6e-05 22.4 0.1 2.2 8.2 0.0 3.6 3 0 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 EMR61702.1 - 0.00012 22.1 3.9 0.095 12.7 0.1 3.8 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.1 EMR61702.1 - 0.0018 18.0 1.1 0.022 14.5 0.1 3.0 3 0 0 3 3 3 1 Thioredoxin domain DSBA PF01323.15 EMR61702.1 - 0.016 14.7 0.1 7.3 6.1 0.0 3.6 3 1 1 4 4 4 0 DSBA-like thioredoxin domain NMD3 PF04981.8 EMR61702.1 - 0.053 12.6 0.0 4.3 6.3 0.0 2.3 2 0 0 2 2 2 0 NMD3 family Methyltransf_15 PF09445.5 EMR61703.1 - 2.6e-31 108.3 0.0 4.5e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EMR61703.1 - 0.0053 16.7 0.1 0.0093 15.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR61703.1 - 0.0059 17.1 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR61703.1 - 0.083 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CAP_N PF01213.14 EMR61704.1 - 2.1e-91 306.4 16.9 4.4e-90 302.1 11.7 2.1 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EMR61704.1 - 4.9e-55 185.2 0.1 7.1e-55 184.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal MCM PF00493.18 EMR61705.1 - 1.1e-129 431.9 0.4 1.7e-129 431.4 0.2 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMR61705.1 - 5.9e-17 62.2 0.1 3.1e-16 59.9 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain adh_short PF00106.20 EMR61705.1 - 9.3e-17 61.4 5.5 1.4e-15 57.6 3.8 2.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR61705.1 - 2.4e-09 37.0 1.2 8.7e-09 35.2 0.8 2.0 1 1 0 1 1 1 1 KR domain Mg_chelatase PF01078.16 EMR61705.1 - 5.7e-07 28.9 0.0 6.2e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EMR61705.1 - 0.0057 16.2 0.0 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMR61705.1 - 0.014 14.8 0.0 0.038 13.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain DAD PF02109.11 EMR61706.1 - 2.2e-48 163.0 3.6 2.9e-48 162.6 2.5 1.1 1 0 0 1 1 1 1 DAD family Pex14_N PF04695.8 EMR61706.1 - 0.013 15.5 1.7 0.026 14.5 1.1 1.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Podoplanin PF05808.6 EMR61706.1 - 0.019 14.5 0.8 0.025 14.1 0.5 1.2 1 0 0 1 1 1 0 Podoplanin Rnf-Nqr PF02508.9 EMR61706.1 - 0.03 13.9 0.9 0.035 13.7 0.6 1.2 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein Pil1 PF13805.1 EMR61706.1 - 0.49 9.4 3.8 0.63 9.1 2.6 1.2 1 0 0 1 1 1 0 Eisosome component PIL1 MGC-24 PF05283.6 EMR61706.1 - 0.52 10.0 9.6 0.48 10.1 5.6 1.7 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) MSP1_C PF07462.6 EMR61706.1 - 4.6 5.5 6.1 5.4 5.2 4.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus A_deaminase PF00962.17 EMR61707.1 - 0.00069 18.6 0.0 0.0069 15.3 0.0 2.7 3 1 1 4 4 4 1 Adenosine/AMP deaminase Amidohydro_2 PF04909.9 EMR61707.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.6 1 1 0 1 1 1 0 Amidohydrolase PI31_Prot_N PF11566.3 EMR61708.1 - 5.9e-27 94.1 0.0 9e-27 93.5 0.0 1.3 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EMR61708.1 - 4.7e-10 39.9 21.2 4.7e-10 39.9 14.7 3.6 3 1 1 4 4 4 1 PI31 proteasome regulator NmrA PF05368.8 EMR61709.1 - 3e-20 72.4 0.0 3.9e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR61709.1 - 1.4e-14 54.5 0.2 1.8e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EMR61709.1 - 5e-07 29.0 0.1 6.5e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EMR61709.1 - 0.00021 21.4 1.8 0.0028 17.7 0.1 2.4 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 EMR61709.1 - 0.01 14.5 0.0 0.029 13.0 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EMR61709.1 - 0.12 12.8 1.7 0.44 10.9 0.3 2.5 2 2 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Ribosomal_L32e PF01655.13 EMR61710.1 - 3.9e-47 158.8 0.8 4.6e-47 158.6 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Ecl1 PF12855.2 EMR61711.1 - 0.022 14.0 5.2 0.063 12.5 3.6 1.8 1 0 0 1 1 1 0 Life-span regulatory factor zf-MYND PF01753.13 EMR61711.1 - 0.023 14.5 6.3 0.023 14.5 4.4 2.4 2 0 0 2 2 2 0 MYND finger Vps39_2 PF10367.4 EMR61711.1 - 0.12 12.5 2.0 0.31 11.2 0.4 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Trm112p PF03966.11 EMR61711.1 - 0.17 12.2 1.6 26 5.2 0.4 3.1 2 1 1 3 3 3 0 Trm112p-like protein DUF3138 PF11336.3 EMR61711.1 - 0.37 8.9 4.6 0.51 8.4 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF329 PF03884.9 EMR61711.1 - 0.37 10.3 6.4 0.64 9.6 0.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF329) Zn_Tnp_IS1595 PF12760.2 EMR61711.1 - 4.1 7.2 7.7 19 5.1 2.6 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-RING_4 PF14570.1 EMR61711.1 - 4.9 6.8 8.0 1.2 8.8 0.8 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain HAD PF12710.2 EMR61712.1 - 1.5e-18 67.6 0.0 2.2e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR61712.1 - 3.4e-11 43.9 1.1 2.1e-09 38.1 0.8 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMR61712.1 - 2.4e-08 33.9 0.3 1.9e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMR61712.1 - 5.6e-05 23.4 0.0 0.00014 22.1 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 EMR61712.1 - 0.0014 17.6 0.2 0.0021 17.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Put_Phosphatase PF06888.7 EMR61712.1 - 0.084 12.0 0.1 3.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase Acid_PPase PF12689.2 EMR61712.1 - 0.11 12.0 0.1 0.33 10.5 0.1 1.9 1 1 0 1 1 1 0 Acid Phosphatase Tim44 PF04280.10 EMR61713.1 - 2.3e-08 34.1 0.0 5.5e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Tim44-like domain MBA1 PF07961.6 EMR61713.1 - 2.9e-07 29.5 0.0 3.5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 MBA1-like protein GPI-anchored PF10342.4 EMR61714.1 - 9.8e-06 25.9 0.7 9.4e-05 22.8 0.5 2.3 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family UPF0016 PF01169.14 EMR61715.1 - 2.1e-42 143.1 24.7 2.1e-22 79.0 5.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF718 PF05336.8 EMR61716.1 - 3.8e-34 116.6 0.1 4.4e-34 116.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF718) SLS PF14611.1 EMR61717.1 - 1.1e-26 93.5 8.6 1.1e-26 93.5 5.9 2.3 2 1 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator Daxx PF03344.10 EMR61718.1 - 2.4 6.5 16.2 4.5 5.6 11.2 1.5 1 0 0 1 1 1 0 Daxx Family Autophagy_N PF03986.8 EMR61719.1 - 2.3e-46 157.2 0.1 2.3e-46 157.2 0.1 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EMR61719.1 - 2.4e-22 78.8 1.3 4e-22 78.1 0.3 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EMR61719.1 - 1.4e-14 52.8 0.4 2.4e-14 52.0 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Thioredoxin PF00085.15 EMR61720.1 - 1.4e-07 31.1 0.0 2.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EMR61720.1 - 0.00097 18.7 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 EMR61720.1 - 0.003 17.1 0.0 0.0084 15.6 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin DUF953 PF06110.6 EMR61720.1 - 0.0062 15.9 0.1 0.025 14.0 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.1 EMR61720.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.1 EMR61720.1 - 0.019 15.1 0.0 0.16 12.1 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMR61720.1 - 0.051 13.6 0.1 0.45 10.6 0.0 2.0 1 1 0 2 2 2 0 Thioredoxin-like Ribosomal_L37e PF01907.14 EMR61721.1 - 1.5e-27 95.1 13.0 2.1e-27 94.6 9.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EMR61721.1 - 0.0029 17.3 2.1 0.0046 16.7 1.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EMR61721.1 - 0.074 12.2 1.9 0.27 10.4 1.3 1.9 1 1 2 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EMR61721.1 - 0.18 11.3 3.2 5.6 6.5 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain GFA PF04828.9 EMR61721.1 - 0.56 10.1 4.7 17 5.4 3.3 2.2 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4 PF00097.20 EMR61721.1 - 2.5 7.8 6.0 4.2 7.1 4.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.16 EMR61721.1 - 2.8 7.3 10.2 2.1 7.7 0.2 2.5 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e GTP_EFTU PF00009.22 EMR61722.1 - 3.3e-57 192.9 0.0 5e-57 192.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMR61722.1 - 3.5e-36 123.3 0.1 1e-35 121.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMR61722.1 - 1.3e-16 60.4 1.8 1.3e-16 60.4 1.3 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EMR61722.1 - 0.00061 19.3 0.3 0.0016 18.0 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EMR61722.1 - 0.0009 19.1 0.1 0.0026 17.6 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase MAGE PF01454.14 EMR61723.1 - 1.2e-45 155.2 0.0 1.5e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 MAGE family DUF702 PF05142.7 EMR61723.1 - 0.24 11.5 1.2 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF702) SF3b10 PF07189.6 EMR61724.1 - 3.6e-41 138.8 0.0 4.1e-41 138.6 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Sugar_tr PF00083.19 EMR61725.1 - 1.4e-44 152.4 7.7 6.8e-36 123.8 0.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR61725.1 - 2.5e-11 42.9 7.6 2.4e-10 39.6 5.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily GP41 PF00517.12 EMR61725.1 - 0.13 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Retroviral envelope protein Xan_ur_permease PF00860.15 EMR61726.1 - 7.3e-24 83.9 31.7 6.6e-23 80.8 19.0 2.8 2 1 0 2 2 2 1 Permease family Sulfate_transp PF00916.15 EMR61726.1 - 3e-05 23.1 3.8 3e-05 23.1 2.7 2.2 2 1 1 3 3 3 1 Sulfate transporter family EOS1 PF12326.3 EMR61727.1 - 2.8e-25 88.7 16.1 1.5e-22 79.8 7.8 2.2 1 1 1 2 2 2 2 N-glycosylation protein PAPS_reduct PF01507.14 EMR61728.1 - 9.9e-43 145.9 0.0 1.5e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Adaptin_N PF01602.15 EMR61729.1 - 3.5e-113 378.7 0.4 4.5e-113 378.3 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EMR61729.1 - 3e-58 195.9 1.7 5.9e-58 194.9 1.2 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EMR61729.1 - 1.5e-15 57.2 1.9 2.1e-05 24.7 0.1 6.1 2 1 3 5 5 5 3 HEAT repeats HEAT_PBS PF03130.11 EMR61729.1 - 0.00047 20.3 0.7 0.98 10.0 0.0 4.6 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat CLASP_N PF12348.3 EMR61729.1 - 0.0051 16.1 3.8 0.02 14.2 0.2 3.0 3 0 0 3 3 3 1 CLASP N terminal DUF3730 PF12530.3 EMR61729.1 - 0.03 14.2 2.3 1 9.2 0.6 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3730) HEAT_EZ PF13513.1 EMR61729.1 - 0.61 10.6 5.1 0.8 10.2 0.7 3.2 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.17 EMR61729.1 - 3.7 7.8 12.5 2 8.7 0.2 4.9 7 0 0 7 7 7 0 HEAT repeat SUI1 PF01253.17 EMR61730.1 - 1.6e-28 98.3 3.3 2.1e-28 97.9 2.3 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 NUDIX PF00293.23 EMR61733.1 - 1.8e-05 24.4 0.1 2.9e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain YbjQ_1 PF01906.12 EMR61734.1 - 0.00065 20.0 3.6 0.0012 19.1 2.5 1.5 1 0 0 1 1 1 1 Putative heavy-metal-binding FLO_LFY PF01698.11 EMR61734.1 - 0.002 17.0 3.8 0.0023 16.8 2.6 1.0 1 0 0 1 1 1 1 Floricaula / Leafy protein BLVR PF06375.6 EMR61734.1 - 0.0041 16.9 6.8 0.0045 16.8 4.7 1.1 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) Gag_spuma PF03276.9 EMR61734.1 - 0.0088 14.4 4.3 0.01 14.1 3.0 1.0 1 0 0 1 1 1 1 Spumavirus gag protein Mpp10 PF04006.7 EMR61734.1 - 0.0099 14.2 4.9 0.01 14.2 3.4 1.0 1 0 0 1 1 1 1 Mpp10 protein Glypican PF01153.14 EMR61734.1 - 0.023 13.3 0.6 0.024 13.2 0.4 1.0 1 0 0 1 1 1 0 Glypican DUF3353 PF11833.3 EMR61734.1 - 0.027 13.9 1.6 0.035 13.5 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) DUF912 PF06024.7 EMR61734.1 - 0.029 14.4 4.3 0.039 14.0 3.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pox_Ag35 PF03286.9 EMR61734.1 - 0.037 13.5 8.1 0.045 13.2 5.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Protocadherin PF08374.6 EMR61734.1 - 0.039 13.5 3.8 0.042 13.4 2.6 1.1 1 0 0 1 1 1 0 Protocadherin NST1 PF13945.1 EMR61734.1 - 0.053 13.5 7.9 0.065 13.2 5.4 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF2956 PF11169.3 EMR61734.1 - 0.062 13.2 6.4 0.081 12.8 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Apis_Csd PF11671.3 EMR61734.1 - 0.12 12.1 8.6 0.16 11.7 5.9 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein Menin PF05053.8 EMR61734.1 - 0.18 9.8 3.6 0.18 9.9 2.5 1.1 1 0 0 1 1 1 0 Menin TAF1D PF15333.1 EMR61734.1 - 0.24 11.1 8.6 0.3 10.8 6.0 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D DUF1168 PF06658.7 EMR61734.1 - 0.32 10.5 17.1 0.42 10.1 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) NARP1 PF12569.3 EMR61734.1 - 0.36 9.5 8.6 0.39 9.4 5.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1754 PF08555.5 EMR61734.1 - 0.72 10.4 17.7 0.99 10.0 12.2 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Eapp_C PF10238.4 EMR61734.1 - 0.75 9.6 8.9 1.1 9.1 6.2 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Peroxin-13_N PF04088.8 EMR61734.1 - 1.1 9.2 3.6 1.4 8.9 2.5 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region SR-25 PF10500.4 EMR61734.1 - 1.1 8.6 12.0 1.4 8.3 8.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.5 EMR61734.1 - 1.3 8.8 8.7 2 8.1 6.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PH_4 PF15404.1 EMR61734.1 - 1.6 8.2 7.2 1.8 8.0 5.0 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain DUF2457 PF10446.4 EMR61734.1 - 1.8 7.1 9.6 2.3 6.8 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NPR3 PF03666.8 EMR61734.1 - 2.3 6.6 8.0 2.8 6.3 5.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 OSTbeta PF15048.1 EMR61734.1 - 3.4 7.7 7.3 4.7 7.2 5.1 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein PAP2 PF01569.16 EMR61735.1 - 1e-18 67.2 0.8 2.3e-18 66.0 0.5 1.6 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 EMR61735.1 - 0.002 18.3 0.1 0.0074 16.5 0.1 1.9 1 1 0 1 1 1 1 PAP2 superfamily C-terminal PAP2_3 PF14378.1 EMR61735.1 - 0.068 12.6 2.9 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 PAP2 superfamily Nol1_Nop2_Fmu PF01189.12 EMR61736.1 - 2.8e-98 328.7 0.0 1.3e-97 326.5 0.0 2.0 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EMR61736.1 - 0.0066 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.12 EMR61736.1 - 0.13 11.1 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Cofilin_ADF PF00241.15 EMR61737.1 - 2.4e-22 79.1 0.0 2.7e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Blt1 PF12754.2 EMR61738.1 - 1.6e-31 110.0 0.2 1.3e-29 103.8 0.2 2.3 1 1 0 1 1 1 1 Cell-cycle control medial ring component ubiquitin PF00240.18 EMR61738.1 - 0.0017 17.7 0.0 0.0026 17.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Cutinase PF01083.17 EMR61739.1 - 8.8e-43 146.1 0.1 1.1e-42 145.8 0.1 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EMR61739.1 - 1.9e-06 27.4 0.0 3.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.11 EMR61739.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FSH1 PF03959.8 EMR61739.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) VirJ PF06057.6 EMR61739.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF2296 PF10058.4 EMR61740.1 - 1.2e-18 66.6 0.1 2e-18 65.8 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) CYTL1 PF15153.1 EMR61740.1 - 0.047 13.3 0.0 0.53 9.9 0.0 2.4 3 0 0 3 3 3 0 Cytokine-like protein 1 zf-RanBP PF00641.13 EMR61740.1 - 0.38 9.8 3.1 0.2 10.7 0.3 1.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF605 PF04652.11 EMR61740.1 - 1.6 8.0 11.8 2.3 7.5 8.2 1.2 1 0 0 1 1 1 0 Vta1 like GRIP PF01465.15 EMR61742.1 - 1.7e-14 53.0 0.0 3.5e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 GRIP domain WEMBL PF05701.6 EMR61742.1 - 5.5e-06 25.1 136.6 0.0002 19.9 18.5 5.7 3 1 3 6 6 6 3 Weak chloroplast movement under blue light IncA PF04156.9 EMR61742.1 - 8.8e-05 22.1 139.3 0.48 9.9 15.6 8.7 3 2 5 8 8 8 2 IncA protein GAS PF13851.1 EMR61742.1 - 0.00016 20.9 122.6 0.032 13.4 12.5 8.5 3 2 5 8 8 8 5 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.6 EMR61742.1 - 0.0018 17.7 9.5 0.0018 17.7 6.6 9.4 4 3 3 8 8 7 4 Phage minor structural protein GP20 ERM PF00769.14 EMR61742.1 - 0.0033 16.9 19.9 0.0033 16.9 13.8 7.1 1 1 7 8 8 8 3 Ezrin/radixin/moesin family Fib_alpha PF08702.5 EMR61742.1 - 0.0065 16.6 6.3 0.0065 16.6 4.3 8.4 4 3 3 9 9 9 2 Fibrinogen alpha/beta chain family Filament PF00038.16 EMR61742.1 - 0.0087 15.5 124.9 0.17 11.2 14.2 9.5 3 2 5 8 8 7 3 Intermediate filament protein Reo_sigmaC PF04582.7 EMR61742.1 - 0.013 14.6 49.7 1.2 8.2 1.9 7.3 3 2 4 8 8 8 0 Reovirus sigma C capsid protein Cep57_CLD_2 PF14197.1 EMR61742.1 - 0.016 15.1 1.1 0.016 15.1 0.8 12.6 6 2 6 12 12 9 0 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.4 EMR61742.1 - 0.029 14.2 139.3 0.19 11.5 0.8 9.2 3 2 6 9 9 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EMR61742.1 - 0.042 11.5 151.0 0.013 13.2 19.3 4.8 3 2 1 4 4 4 0 Myosin tail TPR_MLP1_2 PF07926.7 EMR61742.1 - 0.054 13.2 129.8 0.12 12.1 13.5 10.1 4 3 3 7 7 7 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 EMR61742.1 - 0.065 11.6 97.5 0.057 11.8 15.5 6.0 3 1 3 6 6 6 0 AAA domain APG6 PF04111.7 EMR61742.1 - 0.079 11.9 125.3 0.2 10.6 13.5 7.8 3 2 4 7 7 7 0 Autophagy protein Apg6 YvrJ PF12841.2 EMR61742.1 - 1.8 7.9 10.3 1.1 8.6 0.5 4.6 3 0 0 3 3 3 0 YvrJ protein family TBPIP PF07106.8 EMR61742.1 - 1.9 7.9 103.7 0.16 11.5 0.4 11.4 3 2 8 11 11 11 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RCR PF12273.3 EMR61743.1 - 2e-20 73.6 8.0 3.1e-20 73.0 5.6 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 EMR61743.1 - 5.9e-05 22.8 0.1 7.6e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) PgaD PF13994.1 EMR61743.1 - 0.015 14.7 1.6 0.022 14.2 1.1 1.2 1 0 0 1 1 1 0 PgaD-like protein Hum_adeno_E3A PF05393.6 EMR61743.1 - 0.016 14.8 1.8 0.026 14.1 1.2 1.3 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Herpes_gE PF02480.11 EMR61743.1 - 0.046 12.0 0.1 0.063 11.5 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3328 PF11807.3 EMR61743.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) RNA_pol_Rpb2_6 PF00562.23 EMR61744.1 - 1.2e-113 379.7 0.4 1.6e-113 379.3 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_2 PF04561.9 EMR61744.1 - 3.7e-25 88.4 0.0 7e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_1 PF04563.10 EMR61744.1 - 7e-25 87.1 0.0 1.1e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EMR61744.1 - 9.1e-25 86.2 0.0 2.3e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EMR61744.1 - 3.9e-21 74.7 0.0 9.1e-21 73.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EMR61744.1 - 4.2e-15 55.7 0.0 1.9e-14 53.6 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EMR61744.1 - 0.00023 21.0 0.1 0.00059 19.7 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Arf PF00025.16 EMR61745.1 - 5.8e-42 142.8 0.0 6.8e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMR61745.1 - 4.9e-18 65.0 0.0 5.8e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR61745.1 - 3.5e-08 33.9 0.0 6.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EMR61745.1 - 1.3e-06 27.4 0.0 1.9e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.7 EMR61745.1 - 2.2e-05 23.6 0.0 2.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EMR61745.1 - 0.00011 21.4 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMR61745.1 - 0.00022 21.1 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMR61745.1 - 0.0022 17.4 0.0 0.058 12.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EMR61745.1 - 0.039 13.4 0.0 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EMR61745.1 - 0.04 13.2 0.0 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.18 EMR61745.1 - 0.053 13.3 0.1 0.13 12.0 0.1 1.6 1 1 1 2 2 2 0 Dynamin family PTR2 PF00854.16 EMR61746.1 - 8.7e-18 64.2 21.8 1.3e-16 60.3 13.2 3.2 1 1 0 1 1 1 1 POT family DUF1195 PF06708.6 EMR61746.1 - 0.34 10.3 2.1 16 4.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1195) Pex24p PF06398.6 EMR61747.1 - 8.8 5.0 8.2 12 4.5 5.7 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin ADH_N PF08240.7 EMR61748.1 - 1.8e-30 104.8 0.9 1.8e-30 104.8 0.6 2.8 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR61748.1 - 1.2e-13 50.7 0.0 2.1e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR61749.1 - 7.2e-31 106.1 0.5 7.2e-31 106.1 0.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR61749.1 - 3.4e-22 78.3 0.5 5.9e-22 77.6 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR61749.1 - 0.0013 19.5 0.0 0.0031 18.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aminotran_1_2 PF00155.16 EMR61750.1 - 1.2e-36 126.4 0.0 1.5e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EMR61750.1 - 5.3e-07 28.9 0.0 7.8e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EMR61750.1 - 2.4e-05 22.8 0.0 3.4e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EMR61750.1 - 0.013 14.2 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Na_Ca_ex PF01699.19 EMR61751.1 - 1.4e-16 60.3 9.0 1.5e-15 57.0 2.4 2.6 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF2976 PF11190.3 EMR61751.1 - 0.18 11.3 0.1 0.18 11.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) N_methyl_2 PF13544.1 EMR61751.1 - 0.96 9.0 4.8 1.2 8.7 0.0 2.9 2 0 0 2 2 2 0 Type IV pilin N-term methylation site GFxxxE E1-E2_ATPase PF00122.15 EMR61751.1 - 1.6 7.6 7.0 2.3 7.2 0.3 2.5 1 1 2 3 3 3 0 E1-E2 ATPase Sugar_tr PF00083.19 EMR61752.1 - 4.5e-72 243.0 17.8 5.5e-72 242.7 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR61752.1 - 2e-22 79.3 21.0 1.6e-15 56.7 5.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EMR61752.1 - 0.00013 21.9 5.8 0.049 13.6 0.6 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) MFS_2 PF13347.1 EMR61752.1 - 0.00015 20.2 25.1 0.00098 17.6 1.9 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Acyl_transf_1 PF00698.16 EMR61753.1 - 3.3e-45 154.8 0.0 5.7e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EMR61753.1 - 8.5e-30 102.6 0.0 2.1e-29 101.4 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EMR61753.1 - 2.4e-08 33.6 0.3 1.1e-07 31.4 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EMR61753.1 - 0.016 14.9 0.5 4.4 7.1 0.0 3.2 2 1 1 3 3 3 0 N-terminal half of MaoC dehydratase DUF1993 PF09351.5 EMR61754.1 - 1.1e-37 129.4 0.0 1.3e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DeoC PF01791.4 EMR61755.1 - 3.9e-37 127.8 0.4 4.5e-37 127.5 0.3 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase Fungal_trans PF04082.13 EMR61756.1 - 0.023 13.5 0.1 0.027 13.3 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain GOLGA2L5 PF15070.1 EMR61756.1 - 0.11 10.9 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Ank_2 PF12796.2 EMR61757.1 - 1.4e-32 111.8 8.1 3.4e-13 49.7 0.4 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMR61757.1 - 2.8e-20 71.8 6.7 1.1e-08 35.0 0.1 4.5 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EMR61757.1 - 7.6e-20 69.6 12.5 3.6e-08 32.8 0.1 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EMR61757.1 - 3.7e-19 68.6 4.2 1.7e-07 31.5 0.1 3.7 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR61757.1 - 9.9e-15 53.1 6.4 0.00025 20.9 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Cellulase PF00150.13 EMR61759.1 - 5.4e-28 97.9 1.6 7.1e-28 97.6 1.1 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cas_Cas5d PF09704.5 EMR61759.1 - 0.00063 19.4 0.0 0.0009 18.9 0.0 1.3 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas5) Glyco_transf_90 PF05686.7 EMR61760.1 - 3.1e-13 49.2 0.5 1.3e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 Methyltransf_23 PF13489.1 EMR61761.1 - 4.1e-10 39.6 0.0 7.1e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR61761.1 - 4.4e-06 26.3 0.0 1.5e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR61761.1 - 8.6e-05 23.0 0.0 0.00066 20.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR61761.1 - 0.00081 19.8 0.0 0.0021 18.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR61761.1 - 0.003 18.0 0.0 0.0091 16.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR61761.1 - 0.0034 17.4 0.0 0.016 15.1 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 EMR61761.1 - 0.016 14.2 0.0 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 EMR61761.1 - 0.1 12.9 0.0 0.46 10.8 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain DUF1479 PF07350.7 EMR61762.1 - 4.9e-163 542.4 0.0 5.7e-163 542.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 EMR61762.1 - 9.8e-05 22.4 0.3 0.36 10.8 0.1 2.3 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) RrnaAD PF00398.15 EMR61763.1 - 4.6e-05 22.5 0.0 0.00012 21.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase F-box-like PF12937.2 EMR61764.1 - 8.7e-05 22.1 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMR61764.1 - 0.001 18.6 0.0 0.0021 17.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain Cnd1_N PF12922.2 EMR61765.1 - 0.0056 16.3 0.2 0.0056 16.3 0.1 1.9 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Adeno_PIX PF03955.9 EMR61765.1 - 0.0086 16.5 0.4 0.19 12.2 0.0 2.3 1 1 1 2 2 2 1 Adenovirus hexon-associated protein (IX) Ferritin PF00210.19 EMR61765.1 - 0.31 10.7 3.9 0.98 9.1 2.7 1.9 1 1 0 1 1 1 0 Ferritin-like domain DUF2992 PF11208.3 EMR61765.1 - 0.99 9.3 5.1 0.31 10.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) p450 PF00067.17 EMR61766.1 - 1.2e-33 116.3 0.0 1.5e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 KR PF08659.5 EMR61767.1 - 3.4e-52 176.7 0.1 7.8e-52 175.5 0.0 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR61767.1 - 1.3e-42 145.5 0.1 1.3e-42 145.5 0.1 2.4 3 0 0 3 3 2 1 short chain dehydrogenase PS-DH PF14765.1 EMR61767.1 - 5.4e-39 134.1 0.0 1e-38 133.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EMR61767.1 - 2e-30 106.2 0.3 1.4e-29 103.4 0.1 2.3 2 1 0 2 2 2 1 Acyl transferase domain Methyltransf_12 PF08242.7 EMR61767.1 - 1.1e-19 70.7 0.0 2.6e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EMR61767.1 - 9.5e-16 57.5 0.0 4.7e-15 55.2 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EMR61767.1 - 2.3e-13 50.1 0.0 5e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR61767.1 - 1.1e-10 41.5 0.2 5.4e-10 39.3 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.7 EMR61767.1 - 2.6e-10 40.0 0.0 6.4e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 EMR61767.1 - 7.2e-10 39.4 0.0 1.2e-08 35.4 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EMR61767.1 - 2.9e-09 37.8 0.0 1.5e-08 35.5 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EMR61767.1 - 1.3e-08 34.6 0.0 2.9e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR61767.1 - 1.4e-07 31.9 0.0 4.4e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EMR61767.1 - 3.7e-05 23.2 0.0 9.6e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EMR61767.1 - 0.0002 21.6 0.0 0.00061 20.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 EMR61767.1 - 0.00046 19.1 0.0 0.00072 18.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ubie_methyltran PF01209.13 EMR61767.1 - 0.0044 16.1 0.0 0.0093 15.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Epimerase PF01370.16 EMR61767.1 - 0.019 14.3 0.0 0.05 13.0 0.0 1.7 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family YbbR PF07949.7 EMR61767.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 YbbR-like protein NAD_binding_10 PF13460.1 EMR61767.1 - 0.06 13.3 0.9 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 NADH(P)-binding p450 PF00067.17 EMR61768.1 - 1.4e-32 112.8 0.0 7e-17 61.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 NmrA PF05368.8 EMR61769.1 - 2e-09 37.0 0.0 2.8e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family DUF3638 PF12340.3 EMR61770.1 - 9.5e-93 309.3 0.0 1.4e-92 308.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EMR61770.1 - 3.3e-19 67.7 0.6 6.1e-19 66.8 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) AMP-binding PF00501.23 EMR61772.1 - 1.9e-61 207.6 0.0 6.4e-60 202.6 0.0 2.0 1 1 1 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EMR61772.1 - 1.4e-26 93.0 0.0 2.2e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Laminin_EGF PF00053.19 EMR61774.1 - 0.056 13.3 4.6 0.13 12.2 3.2 1.6 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) p450 PF00067.17 EMR61775.1 - 4.4e-40 137.5 0.0 9.9e-40 136.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_M20 PF01546.23 EMR61776.1 - 3.7e-21 75.5 0.1 5.1e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMR61776.1 - 9.9e-13 47.8 0.1 2.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EMR61777.1 - 3.9e-24 85.1 0.0 5.8e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMR61777.1 - 1.8e-11 43.7 0.0 6.5e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMR61777.1 - 0.0016 18.2 0.0 0.0046 16.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 SGL PF08450.7 EMR61778.1 - 3.1e-09 36.5 0.0 9.7e-09 34.9 0.0 1.7 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EMR61778.1 - 0.0018 18.2 0.0 0.0044 17.0 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 EMR61778.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Arylesterase NHL PF01436.16 EMR61778.1 - 0.019 14.8 0.1 3.2 7.8 0.0 2.8 2 0 0 2 2 2 0 NHL repeat EthD PF07110.6 EMR61779.1 - 0.00079 20.3 0.2 0.0084 17.0 0.2 2.0 1 1 0 1 1 1 1 EthD domain SURF6 PF04935.7 EMR61780.1 - 1e-51 175.2 45.7 1e-51 175.2 31.7 3.7 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 EMR61780.1 - 7.4e-06 25.9 2.8 7.4e-06 25.9 2.0 7.3 6 2 0 6 6 6 1 60S ribosome biogenesis protein Rrp14 CAF-1_p150 PF11600.3 EMR61780.1 - 0.00037 19.9 8.7 0.00037 19.9 6.1 3.5 2 1 2 4 4 4 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Tannase PF07519.6 EMR61781.1 - 6.6e-60 203.1 0.1 7.5e-60 202.9 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase RTA1 PF04479.8 EMR61782.1 - 1.4e-48 165.3 14.4 4e-48 163.8 10.0 1.8 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.13 EMR61782.1 - 0.00054 19.8 2.5 0.001 18.9 1.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ALAD PF00490.16 EMR61783.1 - 1.6e-116 388.7 0.0 2e-116 388.4 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase NSP13 PF06460.7 EMR61783.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP13 Peptidase_M28 PF04389.12 EMR61784.1 - 9.3e-35 119.9 0.0 1.4e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMR61784.1 - 1.3e-11 44.1 0.1 2.7e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EMR61784.1 - 0.0015 18.1 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3645 PF12359.3 EMR61784.1 - 0.021 13.9 0.2 1.8 7.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) DUF4288 PF14119.1 EMR61785.1 - 0.15 12.2 0.1 0.33 11.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) Y_phosphatase3 PF13350.1 EMR61788.1 - 5.2e-39 134.1 0.0 8.3e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EMR61788.1 - 1.8e-08 34.3 0.0 5.4e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EMR61788.1 - 9.2e-05 21.8 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EMR61788.1 - 0.0029 16.9 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMR61788.1 - 0.066 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PPR_2 PF13041.1 EMR61790.1 - 1.5e-09 37.6 0.0 0.017 15.0 0.0 4.8 4 1 1 5 5 5 2 PPR repeat family PPR_3 PF13812.1 EMR61790.1 - 3.8e-07 29.8 6.4 0.0016 18.5 0.1 5.6 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 EMR61790.1 - 0.058 13.3 7.6 16 5.7 0.1 4.8 5 0 0 5 5 5 0 PPR repeat PPR_1 PF12854.2 EMR61790.1 - 7.8 6.0 8.8 0.95 8.9 0.1 3.8 4 0 0 4 4 4 0 PPR repeat MFS_1 PF07690.11 EMR61791.1 - 3.9e-15 55.4 53.5 3.9e-15 55.4 37.1 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Ribosomal_S18 PF01084.15 EMR61792.1 - 9.2e-11 41.4 0.1 1.5e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Sensor PF13796.1 EMR61792.1 - 0.14 11.7 0.7 0.23 11.0 0.5 1.2 1 0 0 1 1 1 0 Putative sensor Amidohydro_3 PF07969.6 EMR61793.1 - 1.5e-21 77.0 0.0 9e-17 61.3 0.0 2.1 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EMR61793.1 - 0.012 15.4 0.0 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 Amidohydrolase Amidohydro_1 PF01979.15 EMR61793.1 - 0.017 14.7 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Amidohydrolase family Glyco_transf_34 PF05637.7 EMR61794.1 - 9.7e-70 234.7 0.0 1.2e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EMR61794.1 - 7.1e-05 22.2 0.0 0.33 10.2 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function, DUF273 RINGv PF12906.2 EMR61796.1 - 8.3e-11 41.7 3.8 6e-10 39.0 2.7 2.1 1 1 0 1 1 1 1 RING-variant domain Marek_A PF02124.10 EMR61796.1 - 0.032 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Marek's disease glycoprotein A zf-RING_2 PF13639.1 EMR61796.1 - 0.29 11.0 3.9 0.66 9.8 0.7 2.2 2 0 0 2 2 2 0 Ring finger domain CcoS PF03597.10 EMR61796.1 - 6.1 6.3 10.7 0.055 12.9 1.3 2.1 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type FAD_binding_3 PF01494.14 EMR61797.1 - 5.1e-76 256.0 0.0 6.9e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EMR61797.1 - 6.4e-32 110.4 0.0 1.1e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 EMR61797.1 - 0.00094 19.5 0.0 0.0044 17.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR61797.1 - 0.0054 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EMR61797.1 - 0.0079 15.6 0.8 0.2 11.0 0.0 2.6 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.1 EMR61797.1 - 0.011 16.0 0.1 0.043 14.1 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain HI0933_like PF03486.9 EMR61797.1 - 0.02 13.3 0.0 0.044 12.2 0.0 1.6 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 EMR61797.1 - 0.028 13.3 0.0 0.085 11.7 0.0 1.8 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMR61797.1 - 0.032 14.2 0.0 0.098 12.7 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMR61797.1 - 0.037 13.1 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.14 EMR61797.1 - 0.15 11.2 0.0 0.34 10.0 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 EMR61797.1 - 0.16 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family Pyridoxal_deC PF00282.14 EMR61798.1 - 2.5e-18 65.6 0.0 3.6e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EMR61798.1 - 0.00028 19.7 0.0 0.00048 18.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EMR61798.1 - 0.011 14.8 0.1 0.026 13.5 0.0 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Sugar_tr PF00083.19 EMR61799.1 - 2.5e-86 290.0 25.6 3.1e-86 289.7 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR61799.1 - 5.2e-26 91.2 47.5 5.6e-22 77.9 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Med4 PF10018.4 EMR61800.1 - 0.008 15.5 0.5 0.0091 15.4 0.3 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Tropomyosin_1 PF12718.2 EMR61800.1 - 0.036 13.9 4.1 0.043 13.6 2.8 1.2 1 0 0 1 1 1 0 Tropomyosin like PspA_IM30 PF04012.7 EMR61800.1 - 0.22 10.8 4.6 0.17 11.2 1.5 1.7 1 1 1 2 2 2 0 PspA/IM30 family Ribosomal_L29 PF00831.18 EMR61800.1 - 1.6 8.4 4.7 0.65 9.7 1.3 1.7 2 0 0 2 2 2 0 Ribosomal L29 protein IncA PF04156.9 EMR61800.1 - 2.3 7.7 5.5 7.1 6.1 3.9 1.6 1 1 0 1 1 1 0 IncA protein bZIP_1 PF00170.16 EMR61800.1 - 9.2 6.3 11.5 2 8.4 1.9 2.7 2 1 1 3 3 3 0 bZIP transcription factor Stc1 PF12898.2 EMR61801.1 - 3.4e-18 65.4 3.4 5e-18 64.9 2.3 1.2 1 0 0 1 1 1 1 Stc1 domain DUF2457 PF10446.4 EMR61801.1 - 4.9 5.7 15.0 6.6 5.3 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BCDHK_Adom3 PF10436.4 EMR61803.1 - 4.4e-69 231.1 0.0 7.8e-69 230.3 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EMR61803.1 - 3.2e-17 62.2 0.0 6.5e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMR61803.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sorb PF02208.11 EMR61803.1 - 0.025 13.9 0.2 0.45 9.9 0.0 2.5 2 0 0 2 2 2 0 Sorbin homologous domain RRM_6 PF14259.1 EMR61804.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HupH_C PF04809.8 EMR61804.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region RNA_pol_I_TF PF04090.7 EMR61805.1 - 7.9e-12 44.8 0.0 1.2e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor ETC_C1_NDUFA5 PF04716.9 EMR61806.1 - 1.4e-20 72.5 0.2 1.1e-19 69.6 0.0 2.3 2 0 0 2 2 2 1 ETC complex I subunit conserved region DUF4188 PF13826.1 EMR61806.1 - 0.048 13.7 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) MIF4G PF02854.14 EMR61807.1 - 6.8e-43 146.5 0.0 2.4e-26 92.4 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 EMR61807.1 - 5.1e-33 114.2 20.7 2.6e-19 69.6 10.0 3.1 1 1 1 2 2 2 2 Up-frameshift suppressor 2 CBP4 PF07960.6 EMR61807.1 - 0.051 13.1 0.0 0.051 13.1 0.0 2.8 3 0 0 3 3 3 0 CBP4 Arginosuc_synth PF00764.14 EMR61808.1 - 1.5e-11 43.9 0.0 4.1e-08 32.6 0.0 2.0 1 1 1 2 2 2 2 Arginosuccinate synthase MFS_1 PF07690.11 EMR61809.1 - 1.6e-38 132.3 51.9 1.6e-38 132.3 36.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR61809.1 - 5e-14 51.7 17.3 5e-14 51.7 12.0 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter ADH_zinc_N PF00107.21 EMR61809.1 - 9.7e-09 34.8 0.1 2.3e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR61809.1 - 0.004 16.8 0.0 0.022 14.5 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2530 PF10745.4 EMR61809.1 - 0.028 14.4 8.4 0.48 10.4 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) RRM_1 PF00076.17 EMR61810.1 - 8.9e-06 25.2 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR61810.1 - 5.1e-05 23.1 0.0 0.00013 21.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1998 PF09369.5 EMR61811.1 - 2.4e-15 56.8 0.1 6.8e-15 55.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) DEAD PF00270.24 EMR61811.1 - 4.8e-14 52.1 0.0 9.8e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR61811.1 - 2.8e-10 39.9 0.2 1e-09 38.0 0.1 2.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Ran_BP1 PF00638.13 EMR61812.1 - 9.7e-19 67.6 0.1 1.9e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 RanBP1 domain RTA1 PF04479.8 EMR61813.1 - 1.5e-19 70.3 1.3 2.4e-19 69.7 0.9 1.3 1 0 0 1 1 1 1 RTA1 like protein FUSC-like PF12805.2 EMR61813.1 - 0.99 8.2 5.0 0.29 10.0 1.4 1.6 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Mo-co_dimer PF03404.11 EMR61814.1 - 4.2e-58 194.6 0.2 1.1e-57 193.2 0.0 1.8 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EMR61814.1 - 1.2e-33 115.8 0.0 2e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 EMR61814.1 - 7.4e-29 99.7 0.0 1.3e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EMR61814.1 - 1.3e-22 79.4 0.0 3.7e-22 77.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 EMR61814.1 - 2.5e-11 44.1 0.0 2.1e-10 41.1 0.0 2.2 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EMR61814.1 - 0.055 13.3 0.1 0.26 11.1 0.0 1.9 1 1 0 2 2 2 0 Ferric reductase NAD binding domain Thioredoxin_4 PF13462.1 EMR61814.1 - 0.11 12.4 0.0 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin BAR_2 PF10455.4 EMR61815.1 - 1e-58 198.5 0.2 1.6e-58 197.9 0.1 1.3 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EMR61815.1 - 4.4e-21 75.4 0.2 3.7e-20 72.4 0.1 1.9 1 1 0 1 1 1 1 BAR domain Chitin_synth_2 PF03142.10 EMR61816.1 - 9.9e-22 77.0 2.0 9.9e-22 77.0 1.4 3.1 2 1 1 3 3 3 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EMR61816.1 - 6.9e-19 68.5 0.0 1.8e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMR61816.1 - 1.7e-17 63.7 8.4 1.7e-17 63.7 5.8 2.6 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EMR61816.1 - 0.0088 15.7 0.1 5 6.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Squash PF00299.13 EMR61816.1 - 0.19 11.5 0.8 0.66 9.8 0.3 2.0 2 0 0 2 2 2 0 Squash family serine protease inhibitor 4HBT_3 PF13622.1 EMR61817.1 - 1.5e-41 142.8 1.9 1.7e-41 142.6 1.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily SKG6 PF08693.5 EMR61818.1 - 0.00023 20.4 0.1 0.00053 19.2 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.8 EMR61818.1 - 0.0018 17.0 3.4 0.0021 16.7 0.0 2.1 2 0 0 2 2 2 1 Giardia variant-specific surface protein Podoplanin PF05808.6 EMR61818.1 - 0.01 15.4 0.1 0.016 14.7 0.1 1.3 1 0 0 1 1 1 0 Podoplanin Shisa PF13908.1 EMR61818.1 - 0.01 15.9 0.2 0.046 13.8 0.0 2.1 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator MFS_1 PF07690.11 EMR61819.1 - 8.9e-36 123.3 47.6 8.9e-36 123.3 33.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily S-antigen PF05756.6 EMR61819.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 S-antigen protein FKBP_C PF00254.23 EMR61820.1 - 9.2e-24 83.2 0.0 1.1e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PDZ_2 PF13180.1 EMR61820.1 - 0.077 12.8 0.3 0.2 11.5 0.2 1.6 1 1 1 2 2 2 0 PDZ domain Nop14 PF04147.7 EMR61821.1 - 0.0072 14.3 28.7 0.036 11.9 13.7 2.2 2 0 0 2 2 2 2 Nop14-like family FLO_LFY PF01698.11 EMR61821.1 - 4 6.2 7.1 0.88 8.3 0.2 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein Acylphosphatase PF00708.13 EMR61822.1 - 4.6e-21 74.7 0.4 8.7e-21 73.8 0.3 1.4 1 1 0 1 1 1 1 Acylphosphatase Lactamase_B_3 PF13483.1 EMR61823.1 - 2.4e-05 24.0 0.0 7.5e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF106 PF01956.11 EMR61823.1 - 4 6.9 4.5 1.1e+02 2.2 4.3 2.1 2 0 0 2 2 2 0 Integral membrane protein DUF106 HA2 PF04408.18 EMR61824.1 - 3.5e-26 91.1 0.1 1.3e-25 89.3 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EMR61824.1 - 2.5e-24 85.2 0.0 1.3e-23 83.0 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EMR61824.1 - 2.8e-12 46.2 0.0 7.7e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMR61824.1 - 6e-08 32.3 0.0 1.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMR61824.1 - 5e-05 23.4 0.1 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EMR61824.1 - 0.00079 18.4 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EMR61824.1 - 0.0011 17.8 0.0 0.0027 16.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 EMR61824.1 - 0.0012 18.6 2.1 0.21 11.4 0.0 3.1 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EMR61824.1 - 0.0027 17.3 0.0 0.0077 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 EMR61824.1 - 0.0034 17.1 0.1 0.0069 16.1 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_14 PF13173.1 EMR61824.1 - 0.0077 16.1 0.2 0.063 13.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EMR61824.1 - 0.01 14.7 0.1 0.018 13.8 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.17 EMR61824.1 - 0.012 15.0 0.3 0.027 13.9 0.2 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 EMR61824.1 - 0.027 14.1 0.0 0.027 14.1 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 EMR61824.1 - 0.046 13.1 0.2 10 5.4 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain NACHT PF05729.7 EMR61824.1 - 0.062 12.9 0.1 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EMR61824.1 - 0.068 13.1 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EMR61824.1 - 0.3 11.3 2.7 0.35 11.1 0.0 2.5 4 0 0 4 4 2 0 ABC transporter ChaC PF04752.7 EMR61826.1 - 3.2e-36 124.9 0.0 8.1e-36 123.6 0.0 1.5 1 1 0 1 1 1 1 ChaC-like protein DUF912 PF06024.7 EMR61827.1 - 0.0013 18.7 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) P12 PF12669.2 EMR61827.1 - 0.013 15.6 0.2 0.013 15.6 0.1 1.8 2 1 0 2 2 1 0 Virus attachment protein p12 family SNARE_assoc PF09335.6 EMR61827.1 - 0.025 14.7 0.0 0.028 14.6 0.0 1.1 1 0 0 1 1 1 0 SNARE associated Golgi protein Cytochrom_B561 PF03188.11 EMR61827.1 - 0.056 13.2 0.1 0.068 13.0 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 DUF2615 PF11027.3 EMR61827.1 - 0.079 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF3328 PF11807.3 EMR61827.1 - 0.1 12.2 0.2 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Ctr PF04145.10 EMR61827.1 - 0.12 12.4 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Herpes_gE PF02480.11 EMR61827.1 - 0.13 10.5 0.0 0.13 10.4 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E OAD_gamma PF04277.8 EMR61827.1 - 0.14 12.5 0.1 0.37 11.1 0.0 1.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF1517 PF07466.6 EMR61827.1 - 0.47 9.4 3.1 0.73 8.7 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) RCR PF12273.3 EMR61827.1 - 1.5 9.3 4.1 2.6 8.5 2.8 1.5 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TPP_enzyme_C PF02775.16 EMR61828.1 - 1.5e-46 157.7 0.4 3.6e-46 156.5 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMR61828.1 - 1.1e-35 122.3 0.4 3.2e-35 120.8 0.3 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Helicase_C PF00271.26 EMR61828.1 - 2.3e-06 27.3 0.3 7.3e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMR61828.1 - 7.1e-05 21.7 0.0 0.00017 20.5 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain HpcH_HpaI PF03328.9 EMR61829.1 - 8.5e-36 122.8 0.0 7.1e-34 116.6 0.0 2.0 2 0 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EMR61829.1 - 6.8e-11 41.5 0.0 3.8e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PEPcase_2 PF14010.1 EMR61829.1 - 0.041 12.1 0.0 0.058 11.7 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase PCI PF01399.22 EMR61830.1 - 5.1e-16 58.8 2.4 9.1e-15 54.8 0.0 3.1 3 1 0 3 3 3 1 PCI domain Vps35 PF03635.12 EMR61830.1 - 0.0065 14.6 0.1 0.0087 14.2 0.1 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RRM_1 PF00076.17 EMR61832.1 - 2.6e-18 65.4 0.0 3.3e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR61832.1 - 1.4e-10 40.9 0.0 2.1e-10 40.4 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR61832.1 - 1.2e-06 28.2 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMR61832.1 - 0.0011 18.7 0.0 0.0013 18.4 0.0 1.1 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EMR61832.1 - 0.013 15.3 0.0 0.015 15.1 0.0 1.0 1 0 0 1 1 1 0 RNA binding motif GalKase_gal_bdg PF10509.4 EMR61833.1 - 3.5e-18 64.5 0.0 6.1e-18 63.8 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EMR61833.1 - 4.1e-13 49.3 0.3 2.9e-12 46.6 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EMR61833.1 - 4.4e-13 49.0 1.5 1.7e-12 47.2 1.1 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain RPA_C PF08784.6 EMR61833.1 - 0.047 14.0 0.2 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Replication protein A C terminal Sigma70_r4 PF04545.11 EMR61833.1 - 0.077 12.3 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4_2 PF08281.7 EMR61833.1 - 0.081 12.3 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 GTP_EFTU PF00009.22 EMR61834.1 - 3.3e-38 131.0 0.1 5.3e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EMR61834.1 - 1.6e-36 124.1 0.2 3.4e-36 123.1 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EMR61834.1 - 5.5e-11 42.4 0.3 1.1e-10 41.4 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMR61834.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Hep_59 PF07052.6 EMR61835.1 - 1.2e-08 35.1 2.5 1.2e-08 35.1 1.7 3.3 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 MxiH PF09392.5 EMR61835.1 - 0.036 14.6 0.4 0.16 12.5 0.3 2.1 1 0 0 1 1 1 0 Type III secretion needle MxiH like BTV_NS2 PF04514.7 EMR61835.1 - 1.2 7.9 5.8 0.29 9.9 1.4 2.0 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 MSP1_C PF07462.6 EMR61835.1 - 4.4 5.5 6.3 3.1 6.0 0.3 2.3 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus ADK PF00406.17 EMR61837.1 - 9.9e-44 148.8 0.0 1.7e-43 148.0 0.0 1.4 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EMR61837.1 - 2.8e-08 34.1 0.0 4.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMR61837.1 - 7.4e-08 33.2 0.0 1.4e-07 32.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMR61837.1 - 9.4e-07 28.8 0.1 4.1e-06 26.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EMR61837.1 - 4.7e-05 22.8 0.1 0.051 12.9 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Rap1-DNA-bind PF09197.5 EMR61837.1 - 0.058 13.9 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 Rap1, DNA-binding PAS_7 PF12860.2 EMR61837.1 - 0.12 12.4 0.0 6.9 6.7 0.0 2.1 2 0 0 2 2 2 0 PAS fold PD40 PF07676.7 EMR61837.1 - 0.13 11.9 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 EMR61838.1 - 2.8e-25 87.2 8.1 1.6e-06 27.7 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EMR61838.1 - 5.8e-05 21.4 4.6 0.0004 18.6 0.3 3.1 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMR61838.1 - 0.017 13.8 0.1 22 3.6 0.0 3.2 1 1 0 3 3 3 0 Nup133 N terminal like Pkinase PF00069.20 EMR61839.1 - 5.1e-54 183.1 0.0 6.4e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR61839.1 - 1.3e-24 86.6 0.0 5.3e-24 84.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR61839.1 - 0.0034 16.3 0.0 0.0055 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 EMR61839.1 - 0.037 12.8 0.1 0.057 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EMR61839.1 - 0.13 11.5 0.1 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family NADPH_Ox PF08414.5 EMR61839.1 - 0.16 12.0 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase DUF202 PF02656.10 EMR61840.1 - 0.013 15.7 6.3 0.079 13.1 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF3329 PF11808.3 EMR61840.1 - 0.22 11.6 0.9 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) TMA7 PF09072.5 EMR61841.1 - 3.2e-23 81.9 21.6 3.5e-23 81.8 15.0 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Annexin PF00191.15 EMR61842.1 - 2.3e-71 235.6 4.2 2.3e-21 75.4 0.0 4.3 4 0 0 4 4 4 4 Annexin DUF4424 PF14415.1 EMR61842.1 - 0.031 13.7 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) ABC_tran PF00005.22 EMR61844.1 - 4.9e-45 153.1 0.0 2.4e-26 92.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMR61844.1 - 2.5e-31 109.1 13.0 1.7e-15 57.2 5.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EMR61844.1 - 3.8e-14 52.4 0.1 0.00013 21.2 0.0 4.1 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMR61844.1 - 1.1e-10 41.9 0.2 0.00067 19.7 0.0 4.4 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EMR61844.1 - 3.6e-07 30.3 0.3 0.0018 18.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 EMR61844.1 - 1e-06 28.5 0.3 0.00055 19.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.1 EMR61844.1 - 4.5e-06 27.1 0.4 0.0018 18.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMR61844.1 - 1.4e-05 25.1 0.9 0.083 12.8 0.1 3.0 3 0 0 3 3 3 2 AAA ATPase domain T2SE PF00437.15 EMR61844.1 - 2.7e-05 23.2 0.0 0.19 10.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 EMR61844.1 - 0.00013 21.4 3.4 0.017 14.6 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EMR61844.1 - 0.00014 21.3 0.2 0.094 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EMR61844.1 - 0.00023 20.7 0.1 0.15 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain Miro PF08477.8 EMR61844.1 - 0.00029 21.3 0.1 0.52 10.8 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 EMR61844.1 - 0.00044 19.7 0.2 0.095 12.1 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.24 EMR61844.1 - 0.0012 19.0 0.0 5.8 7.1 0.0 3.6 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EMR61844.1 - 0.0027 17.1 0.8 0.098 12.0 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EMR61844.1 - 0.0037 16.9 1.3 0.43 10.2 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EMR61844.1 - 0.0045 16.8 2.4 0.0061 16.3 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_33 PF13671.1 EMR61844.1 - 0.005 16.7 0.1 4.3 7.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EMR61844.1 - 0.0055 16.6 0.0 5.8 6.8 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 EMR61844.1 - 0.0072 16.0 0.0 0.34 10.5 0.0 2.8 3 0 0 3 3 3 1 Archaeal ATPase DUF258 PF03193.11 EMR61844.1 - 0.0088 15.2 0.0 2.8 7.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EMR61844.1 - 0.011 14.8 1.3 2.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 EMR61844.1 - 0.026 14.4 0.0 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pox_A32 PF04665.7 EMR61844.1 - 0.03 13.6 0.4 6.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein UPF0079 PF02367.12 EMR61844.1 - 0.058 13.0 0.4 0.34 10.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EMR61844.1 - 0.059 13.6 0.0 5.6 7.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.1 EMR61844.1 - 0.068 12.9 4.8 1.9 8.2 0.1 3.0 3 0 0 3 3 2 0 Part of AAA domain DUF2075 PF09848.4 EMR61844.1 - 0.092 11.6 0.6 12 4.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EMR61844.1 - 0.12 12.5 0.0 13 6.0 0.0 2.9 3 0 0 3 3 2 0 RNA helicase ATP_bind_1 PF03029.12 EMR61844.1 - 0.12 11.9 0.6 17 4.8 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.4 EMR61844.1 - 0.19 10.2 2.5 3.2 6.2 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.18 EMR61844.1 - 0.28 10.9 1.6 16 5.3 0.1 2.5 2 0 0 2 2 2 0 Dynamin family EF-hand_1 PF00036.27 EMR61845.1 - 6.3e-26 87.6 6.8 1.1e-06 27.5 0.1 5.4 5 1 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 EMR61845.1 - 4.4e-24 84.4 4.0 3e-09 36.8 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 EMR61845.1 - 2.8e-21 74.8 7.2 1.2e-09 37.6 0.0 4.2 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EMR61845.1 - 9.2e-21 71.8 6.6 0.00021 20.8 0.1 4.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EMR61845.1 - 4.1e-18 63.8 9.4 4.7e-05 22.5 0.2 4.5 4 0 0 4 4 4 4 EF hand DAO PF01266.19 EMR61846.1 - 2e-20 73.0 0.1 2.8e-20 72.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR61846.1 - 0.012 15.6 0.0 0.032 14.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF1188 PF06690.6 EMR61846.1 - 0.12 11.4 0.0 0.45 9.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Cupin_2 PF07883.6 EMR61847.1 - 9.9e-10 37.7 0.1 2.1e-09 36.7 0.1 1.6 1 1 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EMR61847.1 - 0.0062 16.1 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 Cupin MFS_1 PF07690.11 EMR61849.1 - 3.2e-32 111.6 48.9 1.4e-31 109.4 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR61849.1 - 6.3e-12 44.8 33.3 9.4e-08 31.0 5.7 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.2 EMR61849.1 - 0.00074 19.2 3.5 0.81 9.5 0.1 3.4 3 0 0 3 3 3 2 MFS_1 like family Ank_2 PF12796.2 EMR61850.1 - 2.8e-22 78.8 2.9 4.3e-06 26.9 0.1 5.0 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMR61850.1 - 1.3e-14 54.2 3.6 0.0097 16.3 0.0 6.6 5 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 EMR61850.1 - 1.3e-13 50.0 5.5 0.11 12.3 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.1 EMR61850.1 - 4.2e-11 41.9 4.1 0.37 11.1 0.0 8.8 10 1 1 11 11 11 2 Ankyrin repeat Ank_5 PF13857.1 EMR61850.1 - 8.2e-07 29.0 3.1 6.3 7.1 0.0 6.7 4 2 3 7 7 7 3 Ankyrin repeats (many copies) adh_short PF00106.20 EMR61851.1 - 2.6e-13 50.2 3.1 5.9e-11 42.5 2.1 2.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR61851.1 - 0.00018 21.2 1.0 0.001 18.7 0.1 2.1 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMR61851.1 - 0.0026 17.8 0.2 0.0058 16.6 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 EMR61851.1 - 0.023 14.2 0.4 0.039 13.4 0.3 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 EMR61851.1 - 0.067 12.9 0.2 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 EMR61851.1 - 0.09 12.4 0.2 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pox_MCEL PF03291.11 EMR61852.1 - 4.5e-63 213.1 0.0 3.1e-33 115.0 0.0 3.4 3 1 0 3 3 3 3 mRNA capping enzyme Methyltransf_12 PF08242.7 EMR61852.1 - 6.1e-08 33.0 0.0 1.4e-06 28.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR61852.1 - 7.3e-08 32.9 0.0 1.7e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR61852.1 - 2.1e-07 31.3 0.0 2.1e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR61852.1 - 4.9e-05 23.0 0.1 0.00012 21.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR61852.1 - 0.00029 21.1 0.0 0.0014 18.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR61852.1 - 0.0012 18.4 0.0 0.01 15.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EMR61852.1 - 0.0028 16.6 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Ribosomal_60s PF00428.14 EMR61852.1 - 0.023 15.1 3.4 0.023 15.1 2.3 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Methyltransf_26 PF13659.1 EMR61852.1 - 0.037 14.0 0.5 0.24 11.4 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain DDRGK PF09756.4 EMR61852.1 - 0.99 8.7 6.8 0.1 11.9 1.0 1.9 2 0 0 2 2 2 0 DDRGK domain DUF2360 PF10152.4 EMR61852.1 - 3 8.1 6.9 3.2 8.0 0.2 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Amidase PF01425.16 EMR61853.1 - 1.2e-86 291.2 0.1 1.8e-86 290.7 0.1 1.2 1 0 0 1 1 1 1 Amidase CPSase_L_D2 PF02786.12 EMR61853.1 - 7.5e-64 214.8 0.0 1.3e-63 214.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EMR61853.1 - 6.2e-37 126.0 0.1 2e-36 124.4 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EMR61853.1 - 3.2e-24 84.9 0.0 1.4e-23 82.9 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EMR61853.1 - 2.4e-14 53.4 0.0 6.6e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMR61853.1 - 3.4e-11 42.9 0.0 6.1e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EMR61853.1 - 2.6e-09 36.2 0.0 3.3e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.6 EMR61853.1 - 2.1e-05 24.0 0.0 4.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 EMR61853.1 - 0.0021 17.4 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EMR61853.1 - 0.0023 17.8 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Fungal_trans PF04082.13 EMR61854.1 - 2.2e-11 43.1 1.5 8.1e-07 28.1 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR61854.1 - 1.4e-05 24.8 9.0 2.5e-05 24.0 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.16 EMR61855.1 - 1.5e-34 119.5 0.0 2e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RPN7 PF10602.4 EMR61856.1 - 4.6e-54 182.4 0.2 8.2e-54 181.6 0.2 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EMR61856.1 - 2.7e-14 53.3 0.0 5.8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.1 EMR61856.1 - 0.073 13.7 0.0 0.58 10.9 0.0 2.6 1 0 0 1 1 1 0 Tetratricopeptide repeat COesterase PF00135.23 EMR61857.1 - 6.1e-86 289.2 0.0 2.3e-85 287.3 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR61857.1 - 0.0035 16.9 0.0 0.028 14.0 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Gly_kinase PF02595.10 EMR61859.1 - 1.4e-90 303.7 3.7 1.2e-88 297.4 2.6 2.4 1 1 0 1 1 1 1 Glycerate kinase family MFS_1 PF07690.11 EMR61860.1 - 2.7e-37 128.3 19.8 2.7e-37 128.3 13.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR61860.1 - 2.9e-11 42.6 20.7 1.1e-09 37.3 14.4 3.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR61861.1 - 5.3e-36 124.0 29.4 7e-36 123.6 20.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EMR61861.1 - 0.01 16.2 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1228 PF06779.9 EMR61861.1 - 0.046 13.7 0.8 0.046 13.7 0.5 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) DUF3522 PF12036.3 EMR61861.1 - 3.9 7.2 10.3 0.11 12.3 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) DUF3176 PF11374.3 EMR61862.1 - 3.1e-09 36.6 3.1 5.6e-09 35.8 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) adh_short_C2 PF13561.1 EMR61863.1 - 7.9e-29 101.1 0.0 8.4e-28 97.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR61863.1 - 2.2e-20 73.2 2.4 2.7e-12 46.9 0.1 3.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EMR61863.1 - 2e-06 27.5 0.3 6.7e-05 22.6 0.0 2.4 2 1 0 2 2 2 1 KR domain CDC45 PF02724.9 EMR61865.1 - 0.078 11.0 4.4 0.086 10.8 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 EMR61865.1 - 1.6 6.9 9.4 2.1 6.5 6.5 1.2 1 0 0 1 1 1 0 Transmembrane protein Na_trans_assoc PF06512.8 EMR61865.1 - 2.7 7.8 9.6 0.63 9.9 3.9 1.7 2 0 0 2 2 2 0 Sodium ion transport-associated DUF1510 PF07423.6 EMR61865.1 - 3.7 6.8 13.9 1.2 8.4 7.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) ATP_transf PF09830.4 EMR61866.1 - 9.1e-11 41.3 0.0 1.6e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase Sugar_tr PF00083.19 EMR61867.1 - 1.3e-80 271.2 21.7 5.7e-51 173.4 8.2 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR61867.1 - 9.9e-15 54.0 13.7 9.9e-15 54.0 9.5 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EMR61868.1 - 1.6e-08 33.7 19.1 2.7e-08 32.9 12.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-RanBP PF00641.13 EMR61868.1 - 0.083 12.0 0.1 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others NmrA PF05368.8 EMR61869.1 - 3.7e-12 46.0 0.0 5.1e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR61869.1 - 8.6e-12 45.4 0.1 1.1e-11 45.0 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR61869.1 - 3.7e-05 23.2 0.0 5.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMR61869.1 - 7e-05 22.8 0.2 0.00011 22.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR61869.1 - 0.011 15.4 0.1 0.02 14.5 0.1 1.5 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 EMR61869.1 - 0.049 12.5 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Methyltransf_2 PF00891.13 EMR61870.1 - 2.2e-30 105.6 0.0 1e-29 103.4 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase MarR_2 PF12802.2 EMR61870.1 - 0.0015 18.1 0.1 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 EMR61870.1 - 0.11 12.2 0.0 0.4 10.4 0.0 1.9 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB COX4 PF02936.9 EMR61871.1 - 0.3 10.8 0.1 0.3 10.8 0.1 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV HLH PF00010.21 EMR61872.1 - 1.4e-12 47.1 0.1 3.3e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2413 PF10310.4 EMR61872.1 - 4.2 6.0 15.8 0.3 9.8 6.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) TPR_12 PF13424.1 EMR61873.1 - 2.3e-14 53.0 4.1 2.7e-11 43.2 1.5 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMR61873.1 - 3.4e-10 39.4 9.6 1.2e-06 28.0 2.4 2.7 2 1 1 3 3 3 2 TPR repeat zf-MYND PF01753.13 EMR61873.1 - 4.1e-10 39.3 8.7 6.9e-10 38.6 6.0 1.4 1 0 0 1 1 1 1 MYND finger TPR_1 PF00515.23 EMR61873.1 - 8.6e-10 37.8 6.5 2.9e-05 23.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMR61873.1 - 4.8e-08 32.3 8.5 0.00038 20.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMR61873.1 - 2.3e-07 30.0 3.9 0.22 11.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EMR61873.1 - 3.4e-07 29.9 8.0 0.044 13.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMR61873.1 - 7.9e-05 23.2 20.8 0.0025 18.4 3.7 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat PPR PF01535.15 EMR61873.1 - 0.0023 17.7 0.2 1.2 9.2 0.0 3.4 3 0 0 3 3 3 1 PPR repeat TPR_14 PF13428.1 EMR61873.1 - 0.0028 18.1 14.3 0.15 12.8 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMR61873.1 - 0.0043 17.3 5.1 0.013 15.8 1.2 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMR61873.1 - 0.0081 15.8 1.2 0.033 13.9 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMR61873.1 - 0.16 12.2 4.1 4.5 7.7 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMR61873.1 - 0.17 12.3 15.4 0.88 10.1 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Tropomyosin_1 PF12718.2 EMR61875.1 - 9.1e-05 22.3 0.9 0.00026 20.8 0.6 1.8 1 0 0 1 1 1 1 Tropomyosin like DUF1792 PF08759.6 EMR61875.1 - 0.0042 16.7 0.1 0.12 12.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1792) Tropomyosin PF00261.15 EMR61875.1 - 0.0095 15.0 1.9 0.021 13.8 1.3 1.5 1 0 0 1 1 1 1 Tropomyosin FliD_C PF07195.7 EMR61875.1 - 0.019 14.2 0.5 2.4 7.4 0.6 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Streptin-Immun PF11083.3 EMR61875.1 - 0.056 13.4 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein CBFD_NFYB_HMF PF00808.18 EMR61879.1 - 1.1e-10 41.4 0.6 1.7e-10 40.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMR61879.1 - 1.5e-05 25.0 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Herpes_capsid PF06112.6 EMR61879.1 - 0.05 13.6 10.3 0.1 12.6 7.2 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TFIIA PF03153.8 EMR61879.1 - 0.058 13.2 39.6 0.098 12.5 27.4 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PBP_sp32 PF07222.7 EMR61879.1 - 1.3 8.1 10.9 2.5 7.2 7.5 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CDC27 PF09507.5 EMR61879.1 - 2.2 7.4 36.3 0.55 9.4 23.0 1.6 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Na_K-ATPase PF00287.13 EMR61880.1 - 0.072 11.8 0.5 0.11 11.2 0.3 1.2 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain MFS_1 PF07690.11 EMR61881.1 - 5.5e-32 110.8 24.9 5.5e-32 110.8 17.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR61881.1 - 1.3e-11 43.7 17.2 1.3e-11 43.7 11.9 2.8 2 2 0 2 2 2 1 Sugar (and other) transporter DUF3593 PF12159.3 EMR61881.1 - 0.042 13.6 0.1 0.14 11.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Peroxidase_2 PF01328.12 EMR61882.1 - 1.2e-26 93.1 0.0 1.4e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 PCMT PF01135.14 EMR61884.1 - 1.6e-51 174.8 0.0 5.3e-18 65.3 0.0 3.0 3 0 0 3 3 3 3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EMR61884.1 - 3e-06 26.8 0.0 4.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR61884.1 - 8e-06 26.4 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR61884.1 - 0.00012 22.0 0.1 0.00024 21.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMR61884.1 - 0.00039 20.1 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR61884.1 - 0.0018 17.9 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR61884.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.12 EMR61884.1 - 0.025 13.6 0.0 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_11 PF08241.7 EMR61884.1 - 0.042 14.3 0.1 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 EMR61884.1 - 0.054 12.5 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 EMR61884.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain NmrA PF05368.8 EMR61886.1 - 2.2e-31 108.9 0.0 2.9e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR61886.1 - 1e-20 74.5 0.0 1.6e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Amidohydro_2 PF04909.9 EMR61886.1 - 0.025 14.1 0.0 0.074 12.6 0.0 1.7 2 0 0 2 2 2 0 Amidohydrolase F420_oxidored PF03807.12 EMR61886.1 - 0.13 12.7 0.1 0.55 10.6 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_61 PF03443.9 EMR61887.1 - 4.6e-53 180.2 0.0 5.9e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_M43 PF05572.8 EMR61888.1 - 9.8e-14 51.2 0.1 1.7e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EMR61888.1 - 0.034 14.2 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMR61888.1 - 0.034 14.0 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Lactonase PF10282.4 EMR61889.1 - 1e-82 278.0 0.0 1.3e-82 277.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF2370 PF10176.4 EMR61891.1 - 6.3e-85 284.2 0.0 8.2e-85 283.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Mito_carr PF00153.22 EMR61892.1 - 1.6e-57 191.2 3.3 1.1e-21 76.2 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4574 PF15141.1 EMR61892.1 - 0.14 11.9 0.3 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4574) DUF2613 PF11021.3 EMR61892.1 - 0.86 9.3 4.3 0.35 10.6 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) adh_short PF00106.20 EMR61893.1 - 5e-19 68.8 0.1 6.6e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR61893.1 - 4.7e-11 42.6 0.0 6.4e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR61893.1 - 0.023 14.1 0.2 0.068 12.5 0.1 1.7 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMR61893.1 - 0.046 13.4 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EMR61893.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Complex1_LYR PF05347.10 EMR61894.1 - 0.00086 19.0 0.4 0.0013 18.5 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HTH_Tnp_Tc5 PF03221.11 EMR61894.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Tc5 transposase DNA-binding domain DUF1962 PF09227.5 EMR61895.1 - 7e-35 118.8 19.8 8.4e-35 118.6 13.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1962) Amidohydro_3 PF07969.6 EMR61896.1 - 2.3e-29 102.8 6.8 5.5e-29 101.6 4.7 1.6 1 1 0 1 1 1 1 Amidohydrolase family D-aminoacyl_C PF07908.7 EMR61896.1 - 6.1e-20 70.2 0.6 1.7e-19 68.8 0.4 1.9 1 0 0 1 1 1 1 D-aminoacylase, C-terminal region Amidohydro_5 PF13594.1 EMR61896.1 - 4.4e-11 42.4 0.5 1.4e-10 40.7 0.1 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 EMR61896.1 - 1.1e-08 35.5 7.7 0.00092 19.3 1.9 3.0 2 1 1 3 3 3 2 Amidohydrolase Amidohydro_1 PF01979.15 EMR61896.1 - 0.00018 21.2 0.6 0.28 10.8 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family Ank_2 PF12796.2 EMR61897.1 - 6.2e-32 109.7 0.0 1.7e-13 50.7 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMR61897.1 - 1e-20 72.4 3.5 1e-07 31.3 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EMR61897.1 - 1.8e-15 56.9 0.5 1.9e-06 28.2 0.0 5.5 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR61897.1 - 8.8e-15 54.3 4.6 0.0041 17.3 0.0 5.2 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR61897.1 - 5.1e-13 47.8 6.6 0.00017 21.5 0.0 6.2 7 0 0 7 7 7 3 Ankyrin repeat Spindle_Spc25 PF08234.7 EMR61898.1 - 1.8e-21 75.9 0.3 4.5e-21 74.6 0.0 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.6 EMR61898.1 - 0.0055 15.4 4.1 0.0077 14.9 2.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein THOC7 PF05615.8 EMR61898.1 - 0.24 11.6 13.8 0.031 14.5 6.4 1.7 2 0 0 2 2 2 0 Tho complex subunit 7 Atg14 PF10186.4 EMR61898.1 - 0.26 10.1 11.2 0.42 9.5 7.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 EMR61898.1 - 0.65 8.3 4.6 0.87 7.9 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 EMR61898.1 - 1.1 8.2 9.6 1.6 7.6 6.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 EMR61898.1 - 4.4 7.3 17.3 2.6 8.0 8.9 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AAA_23 PF13476.1 EMR61898.1 - 8.2 6.6 7.4 13 5.9 5.1 1.3 1 0 0 1 1 1 0 AAA domain adh_short PF00106.20 EMR61901.1 - 1.2e-22 80.6 0.0 1.4e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR61901.1 - 3.9e-12 46.1 0.0 4.9e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR61901.1 - 1.7e-10 41.1 0.0 2.1e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR61901.1 - 0.0012 18.3 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMR61901.1 - 0.0094 15.7 0.1 0.032 14.0 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF814 PF05670.8 EMR61902.1 - 3.2e-08 33.3 0.0 1.1e-06 28.3 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF814) Cyt-b5 PF00173.23 EMR61903.1 - 1.2e-09 37.8 0.0 2e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain KOW PF00467.24 EMR61904.1 - 2.8e-08 33.1 1.7 2.8e-08 33.1 1.2 1.9 2 0 0 2 2 2 1 KOW motif DUF1223 PF06764.6 EMR61904.1 - 0.099 12.4 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) Ribosomal_L3 PF00297.17 EMR61905.1 - 8.9e-31 107.2 6.1 2.7e-29 102.3 4.3 2.2 1 1 0 1 1 1 1 Ribosomal protein L3 Acetyltransf_7 PF13508.1 EMR61906.1 - 1.7e-05 24.8 0.0 6.2e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR61906.1 - 2.6e-05 24.1 0.0 0.0012 18.8 0.0 2.9 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 EMR61906.1 - 6.6e-05 23.4 0.0 0.45 11.1 0.0 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Mucin PF01456.12 EMR61906.1 - 0.012 15.4 6.6 0.018 14.8 4.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein MOZART1 PF12554.3 EMR61907.1 - 5.6e-26 89.7 0.5 6.5e-26 89.5 0.3 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DUF3893 PF13032.1 EMR61907.1 - 0.14 12.2 0.1 0.16 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3893) Coa1 PF08695.5 EMR61908.1 - 9.9e-39 131.4 0.0 1.3e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 RskA PF10099.4 EMR61908.1 - 0.14 11.8 1.3 0.28 10.9 0.1 1.9 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Mito_carr PF00153.22 EMR61909.1 - 8.5e-67 220.9 4.3 1.5e-23 82.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S25 PF03297.10 EMR61910.1 - 1.4e-33 115.0 7.9 2.2e-33 114.4 5.5 1.3 1 1 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 EMR61910.1 - 0.0054 16.0 0.1 0.0081 15.5 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 EMR61910.1 - 0.011 15.4 0.1 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_DeoR PF08220.7 EMR61910.1 - 0.017 14.6 0.1 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain DDRGK PF09756.4 EMR61910.1 - 0.02 14.3 0.2 0.024 14.0 0.1 1.0 1 0 0 1 1 1 0 DDRGK domain HTH_11 PF08279.7 EMR61910.1 - 0.061 12.9 0.1 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 HTH domain TrmB PF01978.14 EMR61910.1 - 0.072 12.8 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RNA_pol_Rpc34 PF05158.7 EMR61910.1 - 0.1 11.7 0.2 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit HSP70 PF00012.15 EMR61911.1 - 1e-57 195.4 0.2 1.3e-57 195.1 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMR61911.1 - 7.7e-05 21.4 0.1 0.0013 17.4 0.1 2.3 2 0 0 2 2 2 1 MreB/Mbl protein PITH PF06201.8 EMR61912.1 - 1.1e-43 148.6 0.2 5.2e-43 146.4 0.1 1.8 1 1 0 1 1 1 1 PITH domain Nfu_N PF08712.6 EMR61912.1 - 0.1 12.2 0.6 0.29 10.7 0.1 2.0 3 0 0 3 3 3 0 Scaffold protein Nfu/NifU N terminal CENP-X PF09415.5 EMR61913.1 - 1.4e-25 88.8 0.1 2.9e-25 87.8 0.1 1.6 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CD99L2 PF12301.3 EMR61913.1 - 0.35 10.5 9.4 0.49 10.0 6.5 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 Nucleoplasmin PF03066.10 EMR61913.1 - 2.1 7.8 7.6 2.8 7.4 5.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin MGC-24 PF05283.6 EMR61914.1 - 0.0082 15.9 4.8 0.014 15.1 3.3 1.4 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Cu_bind_like PF02298.12 EMR61914.1 - 0.042 13.6 0.4 0.22 11.3 0.3 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain Ribosomal_S7 PF00177.16 EMR61915.1 - 6.1e-41 139.4 1.1 8.8e-41 138.9 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e ATP-synt_G PF04718.10 EMR61916.1 - 2.5e-28 98.7 0.4 2.5e-28 98.7 0.3 1.9 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF3347 PF11827.3 EMR61916.1 - 0.0074 16.3 2.3 0.065 13.2 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3347) Ras PF00071.17 EMR61917.1 - 3.4e-49 166.3 0.0 3.9e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR61917.1 - 2.1e-16 60.4 0.0 3.3e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMR61917.1 - 5.7e-11 41.9 0.0 6.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMR61917.1 - 7e-05 22.0 0.0 8.3e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMR61917.1 - 0.00016 21.1 0.0 0.00046 19.6 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMR61917.1 - 0.0019 18.1 0.0 0.0025 17.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMR61917.1 - 0.0056 16.8 0.0 0.0094 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EMR61917.1 - 0.0098 15.3 0.0 0.053 12.9 0.0 2.1 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EMR61917.1 - 0.029 14.3 0.1 0.044 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EMR61917.1 - 0.033 14.1 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 EMR61917.1 - 0.076 12.2 0.0 0.17 11.0 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 EMR61917.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EMR61917.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain tRNA-synt_2b PF00587.20 EMR61918.1 - 5.1e-35 120.5 0.3 9e-35 119.7 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EMR61918.1 - 2.3e-19 69.4 7.2 4e-19 68.6 5.0 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 EMR61918.1 - 0.94 9.7 3.2 2.5 8.4 2.3 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 EMR61918.1 - 9 5.1 8.8 13 4.6 6.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_S3Ae PF01015.13 EMR61919.1 - 6.9e-82 273.5 4.5 8.4e-82 273.2 3.1 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family mRNA_cap_C PF03919.10 EMR61919.1 - 0.11 12.8 0.3 0.39 11.0 0.0 2.1 2 1 1 3 3 3 0 mRNA capping enzyme, C-terminal domain TPMT PF05724.6 EMR61920.1 - 9.1e-35 120.0 0.0 1.3e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 EMR61920.1 - 2.6e-11 43.3 0.0 4.7e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EMR61920.1 - 3.7e-10 39.7 0.0 5.5e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR61920.1 - 9.7e-10 39.0 0.0 1.6e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR61920.1 - 6.2e-08 33.0 0.0 1.4e-07 31.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR61920.1 - 2.7e-07 30.9 0.0 7.7e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR61920.1 - 1.8e-06 27.9 0.0 5e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR61920.1 - 3.3e-06 27.3 0.0 4.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EMR61920.1 - 0.00075 18.7 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB AdoMet_MTase PF07757.8 EMR61920.1 - 0.021 14.9 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase N2227 PF07942.7 EMR61920.1 - 0.087 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein CheR PF01739.13 EMR61920.1 - 0.17 11.1 0.0 1.3 8.2 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain UPF0020 PF01170.13 EMR61920.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 HMGL-like PF00682.14 EMR61921.1 - 1.3e-62 211.5 0.2 2.2e-62 210.8 0.1 1.3 1 0 0 1 1 1 1 HMGL-like Longin PF13774.1 EMR61922.1 - 7.8e-15 54.1 0.0 1.5e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EMR61922.1 - 1.9e-14 53.0 0.9 2.9e-14 52.4 0.6 1.2 1 0 0 1 1 1 1 Synaptobrevin Abhydrolase_6 PF12697.2 EMR61923.1 - 4.9e-31 108.3 0.0 6.6e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR61923.1 - 4.9e-20 72.0 0.0 9.5e-20 71.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR61923.1 - 1.7e-13 50.5 0.0 3.2e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMR61923.1 - 3.3e-08 33.4 0.1 4.5e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 EMR61923.1 - 0.0089 15.4 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 EMR61923.1 - 0.0098 16.1 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 EMR61923.1 - 0.015 15.1 0.1 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 EMR61923.1 - 0.019 14.5 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.6 EMR61923.1 - 0.063 12.3 0.0 5.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.9 EMR61923.1 - 0.077 11.4 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydro_lipase PF04083.11 EMR61923.1 - 0.092 12.1 0.4 0.41 10.0 0.0 2.1 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region CAF1-p150_C2 PF15539.1 EMR61923.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Ras PF00071.17 EMR61924.1 - 1.2e-13 50.7 0.0 1.3e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Elf1 PF05129.8 EMR61925.1 - 6.4e-30 102.6 0.9 8.8e-30 102.2 0.6 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 EMR61925.1 - 0.047 13.4 1.1 0.094 12.5 0.8 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Cys_rich_CPXG PF14255.1 EMR61925.1 - 0.063 13.1 0.9 0.095 12.5 0.6 1.4 1 0 0 1 1 1 0 Cysteine-rich CPXCG Zn-ribbon_8 PF09723.5 EMR61925.1 - 0.072 13.0 1.8 0.18 11.8 1.2 1.6 1 1 0 1 1 1 0 Zinc ribbon domain zf-BED PF02892.10 EMR61925.1 - 1.2 8.9 4.1 0.64 9.8 0.4 2.0 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 EMR61925.1 - 4.4 7.3 7.3 1.5 8.7 0.9 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger UPRTase PF14681.1 EMR61926.1 - 2e-80 268.8 0.0 2.8e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EMR61926.1 - 8.2e-05 22.3 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EMR61926.1 - 0.099 12.3 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) GTP_CH_N PF12471.3 EMR61927.1 - 1.2e-80 269.7 0.0 9.2e-80 266.8 0.0 2.0 1 1 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EMR61927.1 - 4e-10 39.1 0.0 8.4e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase II Ank_2 PF12796.2 EMR61928.1 - 1.1e-42 144.3 6.1 1.1e-11 44.8 0.1 6.6 4 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 EMR61928.1 - 3.3e-35 118.1 15.1 2e-07 30.4 0.0 10.1 9 1 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 EMR61928.1 - 5.7e-27 93.6 10.5 2.3e-07 31.1 0.2 9.2 5 3 4 9 9 9 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR61928.1 - 4.7e-24 83.8 20.2 0.0024 18.0 0.5 9.1 8 1 1 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR61928.1 - 1.2e-22 77.6 13.3 0.00011 22.1 0.0 10.1 10 1 0 10 10 10 4 Ankyrin repeat F-box-like PF12937.2 EMR61928.1 - 8.1e-05 22.2 0.0 0.00017 21.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like Sdh_cyt PF01127.17 EMR61929.1 - 7.2e-16 58.1 7.4 1e-15 57.6 5.1 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2-Hacid_dh_C PF02826.14 EMR61930.1 - 2.1e-36 124.7 0.0 1.7e-35 121.8 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMR61930.1 - 4.5e-09 35.8 0.1 8.1e-09 35.0 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMR61930.1 - 6.7e-06 26.0 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.19 EMR61930.1 - 0.0048 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EMR61930.1 - 0.025 14.9 0.1 0.078 13.4 0.1 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 EMR61930.1 - 0.055 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold nec1 PF10379.4 EMR61930.1 - 0.11 11.7 0.5 0.2 10.9 0.4 1.3 1 0 0 1 1 1 0 Virulence protein nec1 TIP120 PF08623.5 EMR61932.1 - 3.6e-57 192.6 3.1 4e-54 182.7 0.0 4.7 3 1 1 4 4 4 2 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EMR61932.1 - 2.3e-16 59.8 26.1 0.00033 20.8 0.0 10.2 8 3 2 10 10 10 6 HEAT repeats HEAT PF02985.17 EMR61932.1 - 2.5e-07 30.2 25.5 0.23 11.6 0.0 10.4 11 0 0 11 11 11 4 HEAT repeat DUF2435 PF10363.4 EMR61932.1 - 0.00013 21.8 7.1 0.017 15.0 0.0 6.3 8 0 0 8 8 8 1 Protein of unknown function (DUF2435) Vac14_Fab1_bd PF12755.2 EMR61932.1 - 0.0017 18.6 4.2 3.4 8.1 0.0 6.5 7 1 0 7 7 7 1 Vacuolar 14 Fab1-binding region ATP-cone PF03477.11 EMR61932.1 - 0.0036 17.7 0.1 21 5.6 0.0 4.6 5 0 0 5 5 5 0 ATP cone domain Proteasom_PSMB PF10508.4 EMR61932.1 - 0.16 10.2 3.5 21 3.2 0.0 4.0 4 1 1 5 5 5 0 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.1 EMR61932.1 - 1.3 9.5 35.1 2 9.0 0.0 11.6 12 3 2 14 14 14 0 HEAT-like repeat MFS_1 PF07690.11 EMR61934.1 - 2.5e-24 85.6 38.4 2.5e-24 85.6 26.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR61934.1 - 4.2e-08 32.1 15.4 4.2e-08 32.1 10.6 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1510 PF07423.6 EMR61935.1 - 0.31 10.3 12.8 1.9 7.7 8.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1546 PF07571.8 EMR61936.1 - 1.9e-28 98.3 0.0 4.6e-28 97.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) TAF PF02969.12 EMR61936.1 - 5.9e-23 80.5 0.1 1.6e-22 79.1 0.0 1.8 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EMR61936.1 - 0.00029 20.8 0.1 0.00054 20.0 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMR61936.1 - 0.064 13.3 0.1 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMR61936.1 - 0.085 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Bromodomain associated CAP59_mtransfer PF11735.3 EMR61937.1 - 3.6e-60 203.1 0.0 5e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DBC1 PF14443.1 EMR61937.1 - 0.015 14.7 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 DBC1 EphA2_TM PF14575.1 EMR61939.1 - 0.33 11.3 1.5 0.7 10.3 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CD20 PF04103.10 EMR61939.1 - 3 7.7 7.5 3.1 7.7 1.1 3.2 3 0 0 3 3 3 0 CD20-like family KAT11 PF08214.6 EMR61940.1 - 1.7e-40 139.2 0.0 1.5e-28 99.8 0.0 2.1 1 1 1 2 2 2 2 Histone acetylation protein adh_short PF00106.20 EMR61941.1 - 2.2e-22 79.7 0.0 3e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR61941.1 - 4.7e-10 39.6 0.0 6.4e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMR61941.1 - 1.1e-06 28.8 0.0 2.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMR61941.1 - 1.9e-05 24.4 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMR61941.1 - 0.00018 21.1 0.8 0.00051 19.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EMR61941.1 - 0.018 13.9 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.16 EMR61941.1 - 0.022 14.1 0.0 0.04 13.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EMR61941.1 - 0.031 13.5 0.0 0.076 12.2 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family DUF1593 PF07632.6 EMR61942.1 - 9.3e-83 277.5 0.0 1.2e-82 277.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) ABC2_membrane PF01061.19 EMR61943.1 - 4.9e-83 277.4 37.1 1.9e-41 141.5 9.7 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EMR61943.1 - 1.2e-43 148.7 0.0 1.2e-22 80.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EMR61943.1 - 2.1e-25 88.3 4.5 1.4e-23 82.5 0.1 3.0 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 EMR61943.1 - 5.7e-14 51.9 25.5 5.8e-11 42.0 4.6 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein SMC_N PF02463.14 EMR61943.1 - 2.2e-07 30.3 0.5 0.16 11.2 0.0 4.3 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EMR61943.1 - 1.1e-05 24.6 0.5 0.00094 18.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMR61943.1 - 1.3e-05 25.2 0.1 0.17 12.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EMR61943.1 - 3.4e-05 23.9 0.0 0.0008 19.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR61943.1 - 3.8e-05 23.7 0.4 0.0079 16.2 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EMR61943.1 - 5.3e-05 22.6 1.0 0.00063 19.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EMR61943.1 - 7.8e-05 22.1 0.1 0.0066 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EMR61943.1 - 0.0003 20.4 0.3 0.044 13.4 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EMR61943.1 - 0.0029 17.1 0.2 0.16 11.4 0.1 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EMR61943.1 - 0.0031 17.5 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMR61943.1 - 0.0055 17.0 0.0 0.32 11.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMR61943.1 - 0.0056 16.4 0.1 3.6 7.4 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EMR61943.1 - 0.0056 16.3 0.5 0.31 10.6 0.1 2.8 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 EMR61943.1 - 0.0061 17.3 0.2 0.079 13.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 EMR61943.1 - 0.0068 16.1 0.0 0.65 9.6 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 EMR61943.1 - 0.011 15.2 0.1 0.47 9.8 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EMR61943.1 - 0.012 15.2 0.1 0.35 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EMR61943.1 - 0.014 15.3 0.0 0.93 9.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase T2SE PF00437.15 EMR61943.1 - 0.024 13.5 0.1 4.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 EMR61943.1 - 0.035 14.5 0.0 0.94 9.9 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein SbcCD_C PF13558.1 EMR61943.1 - 0.038 13.9 0.0 0.5 10.3 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EMR61943.1 - 0.042 14.1 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EMR61943.1 - 0.044 13.9 0.1 21 5.3 0.0 3.0 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EMR61943.1 - 0.045 13.6 0.1 0.26 11.1 0.0 2.4 3 0 0 3 3 1 0 AAA domain NB-ARC PF00931.17 EMR61943.1 - 0.056 12.2 0.2 1.8 7.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain ArgK PF03308.11 EMR61943.1 - 0.099 11.3 0.1 0.3 9.8 0.0 1.7 2 0 0 2 2 2 0 ArgK protein AAA_15 PF13175.1 EMR61943.1 - 0.11 11.5 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Ribosomal_S28e PF01200.13 EMR61943.1 - 0.16 11.7 0.0 23 4.8 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S28e Zeta_toxin PF06414.7 EMR61943.1 - 0.34 9.9 1.1 4.3 6.3 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin Amidohydro_5 PF13594.1 EMR61944.1 - 3.3e-12 46.0 1.5 1.2e-11 44.2 1.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EMR61944.1 - 7.3e-06 25.8 0.5 1.7e-05 24.6 0.2 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMR61944.1 - 0.3 11.0 1.6 1.2 9.1 1.1 2.0 1 1 0 1 1 1 0 Amidohydrolase Amidohydro_3 PF07969.6 EMR61944.1 - 2.3 7.3 5.4 11 5.1 0.5 2.6 1 1 1 2 2 2 0 Amidohydrolase family CCDC71L PF15374.1 EMR61945.1 - 0.018 14.3 0.9 0.02 14.2 0.6 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L DUF1659 PF07872.6 EMR61945.1 - 0.047 13.3 0.5 0.092 12.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) S-antigen PF05756.6 EMR61945.1 - 8.7 6.3 11.7 45 4.1 0.0 2.1 1 1 1 2 2 2 0 S-antigen protein Gamma-thionin PF00304.15 EMR61946.1 - 0.016 15.2 13.2 0.17 11.9 2.0 2.3 2 0 0 2 2 2 0 Gamma-thionin family ACI44 PF15270.1 EMR61946.1 - 0.28 11.1 7.6 0.16 11.9 0.9 2.2 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor Colipase-like PF15083.1 EMR61946.1 - 0.52 10.2 7.4 4 7.4 0.6 2.1 2 0 0 2 2 2 0 Colipase-like Toxin_11 PF07473.6 EMR61946.1 - 0.55 10.1 16.2 0.62 9.9 2.8 2.6 2 0 0 2 2 2 0 Spasmodic peptide gm9a Colipase PF01114.13 EMR61946.1 - 0.69 9.4 17.2 0.45 10.0 3.6 2.3 2 0 0 2 2 2 0 Colipase, N-terminal domain DNase_NucA_NucB PF14040.1 EMR61947.1 - 5.7e-06 26.4 2.4 1.9e-05 24.7 0.5 2.2 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB Acetyltransf_1 PF00583.19 EMR61948.1 - 1.4e-19 69.9 0.1 2.1e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMR61948.1 - 9.8e-10 38.5 0.0 1.2e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR61948.1 - 2.1e-09 36.9 0.0 2.5e-08 33.5 0.0 2.4 3 0 0 3 3 3 1 FR47-like protein Acetyltransf_4 PF13420.1 EMR61948.1 - 8.3e-09 35.5 0.0 1.3e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMR61948.1 - 7.1e-08 32.7 0.0 8.5e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR61948.1 - 2.5e-07 30.7 0.0 3.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMR61948.1 - 2.9e-05 23.9 0.0 4.3e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMR61948.1 - 0.0002 21.1 0.1 0.00053 19.8 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EMR61948.1 - 0.0099 15.7 0.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FMN_bind_2 PF04299.7 EMR61949.1 - 1.1e-52 177.8 0.0 1.3e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Putative FMN-binding domain GMC_oxred_C PF05199.8 EMR61950.1 - 3.8e-38 131.0 0.1 6.4e-38 130.2 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR61950.1 - 4.3e-37 127.8 0.0 3.9e-31 108.3 0.0 2.3 1 1 1 2 2 2 2 GMC oxidoreductase DAO PF01266.19 EMR61950.1 - 8.3e-07 28.2 0.0 0.008 15.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR61950.1 - 1.8e-05 24.6 0.0 5.2e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMR61950.1 - 9.8e-05 21.4 0.0 0.00042 19.3 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMR61950.1 - 0.00023 21.1 0.0 0.093 12.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR61950.1 - 0.00096 19.2 0.2 0.52 10.3 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR61950.1 - 0.0023 17.7 0.2 0.075 12.8 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EMR61950.1 - 0.003 16.4 0.0 0.72 8.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 EMR61950.1 - 0.0076 15.1 0.4 0.33 9.7 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Antimicrobial10 PF08105.6 EMR61950.1 - 0.098 12.2 0.1 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Metchnikowin family Ribonucleas_3_3 PF14622.1 EMR61952.1 - 1.1e-25 90.0 0.0 2.5e-25 88.9 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EMR61952.1 - 0.13 12.7 0.0 0.68 10.4 0.0 2.0 1 1 0 1 1 1 0 Ribonuclease III domain Casc1 PF12366.3 EMR61955.1 - 0.054 12.9 1.1 0.19 11.1 0.7 1.8 1 1 0 1 1 1 0 Cancer susceptibility candidate 1 Glyco_hydro_61 PF03443.9 EMR61956.1 - 3.9e-48 164.1 0.0 4.5e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Beta_elim_lyase PF01212.16 EMR61957.1 - 4.4e-53 180.3 0.0 5.3e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EMR61957.1 - 5e-05 21.7 0.0 6.7e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EMR61957.1 - 0.00016 20.8 0.1 0.00029 19.9 0.1 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EMR61957.1 - 0.00039 19.4 0.0 0.00052 19.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMR61957.1 - 0.03 13.0 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V MR_MLE_C PF13378.1 EMR61957.1 - 0.043 13.7 0.1 1.4 8.8 0.0 2.8 3 0 0 3 3 3 0 Enolase C-terminal domain-like OKR_DC_1 PF01276.15 EMR61957.1 - 0.13 10.7 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain TRI12 PF06609.8 EMR61958.1 - 3.9e-38 131.0 34.1 6.5e-16 57.6 4.0 3.0 1 1 1 3 3 3 3 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EMR61958.1 - 1.9e-11 43.3 44.1 1.9e-11 43.3 30.6 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_92 PF07971.7 EMR61961.1 - 2.7e-142 474.9 3.7 3.6e-142 474.5 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Bac_rhodopsin PF01036.13 EMR61963.1 - 9.9e-58 195.0 14.1 1.3e-57 194.6 9.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 EMR61963.1 - 2.8 7.3 8.4 8.5 5.7 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Methyltransf_23 PF13489.1 EMR61965.1 - 6.7e-17 61.6 0.0 9.2e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR61965.1 - 2.3e-14 53.6 0.0 5e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR61965.1 - 2.1e-11 43.6 0.0 5.8e-10 38.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR61965.1 - 2.6e-10 40.6 0.0 2.3e-09 37.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR61965.1 - 7.1e-09 36.2 0.0 1.1e-07 32.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR61965.1 - 2.9e-07 29.8 0.0 3.3e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMR61965.1 - 1.4e-06 28.5 0.0 4.3e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR61965.1 - 0.0039 17.1 0.0 0.021 14.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EMR61965.1 - 0.02 14.5 0.0 0.15 11.6 0.0 2.3 2 1 0 2 2 2 0 Hypothetical methyltransferase CMAS PF02353.15 EMR61965.1 - 0.023 13.7 0.0 0.035 13.1 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EMR61965.1 - 0.024 13.6 0.0 0.097 11.7 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase UPF0146 PF03686.8 EMR61965.1 - 0.03 14.1 0.0 0.071 12.9 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Diphthamide_syn PF01866.12 EMR61966.1 - 5.1e-46 157.3 0.0 3.7e-45 154.4 0.0 2.1 1 1 0 1 1 1 1 Putative diphthamide synthesis protein YqfQ PF14181.1 EMR61966.1 - 0.73 9.8 5.7 0.094 12.7 0.6 1.9 2 0 0 2 2 2 0 YqfQ-like protein Transferase PF02458.10 EMR61967.1 - 9.1e-08 30.9 0.0 1.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Transferase family DUF758 PF05527.6 EMR61968.1 - 0.0098 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF758) PAF-AH_p_II PF03403.8 EMR61969.1 - 6.5e-27 93.8 0.0 9.2e-26 90.0 0.0 2.1 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EMR61969.1 - 3.2e-13 49.6 0.2 5.2e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMR61969.1 - 1.6e-08 33.7 0.0 0.00016 20.6 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.6 EMR61969.1 - 2e-06 26.8 0.1 0.0019 17.0 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase Abhydrolase_6 PF12697.2 EMR61969.1 - 2.4e-05 24.3 7.8 5.9e-05 23.0 5.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMR61969.1 - 0.06 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF4136 PF13590.1 EMR61970.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4136) AAA PF00004.24 EMR61971.1 - 1.5e-18 67.2 0.0 8.2e-18 64.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMR61971.1 - 0.0022 18.7 0.0 0.044 14.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EMR61971.1 - 0.01 15.9 0.2 0.59 10.2 0.0 2.5 1 1 1 2 2 2 0 AAA domain RuvB_N PF05496.7 EMR61971.1 - 0.034 13.1 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EMR61971.1 - 0.051 13.5 0.3 0.2 11.6 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 EMR61971.1 - 0.052 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EMR61971.1 - 0.12 12.6 0.0 0.59 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 EMR61972.1 - 1e-18 67.1 31.7 4.3e-18 65.1 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_17 PF13207.1 EMR61973.1 - 5.9e-05 23.8 0.0 0.00011 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMR61973.1 - 7.2e-05 22.9 0.0 0.00018 21.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMR61973.1 - 0.00016 21.7 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EMR61973.1 - 0.00021 21.5 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EMR61973.1 - 0.0011 19.3 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMR61973.1 - 0.0038 16.3 0.1 0.008 15.2 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin KTI12 PF08433.5 EMR61973.1 - 0.005 16.0 0.0 0.0093 15.2 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Complex1_LYR_1 PF13232.1 EMR61973.1 - 0.005 17.0 0.3 0.031 14.4 0.2 2.3 1 1 0 1 1 1 1 Complex1_LYR-like AAA_5 PF07728.9 EMR61973.1 - 0.011 15.4 0.0 0.038 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EMR61973.1 - 0.021 14.5 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EMR61973.1 - 0.026 14.7 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 EMR61973.1 - 0.029 13.9 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMR61973.1 - 0.037 13.8 0.0 0.09 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EMR61973.1 - 0.038 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ArgK PF03308.11 EMR61973.1 - 0.039 12.7 0.3 0.21 10.3 0.0 1.9 2 0 0 2 2 2 0 ArgK protein Torsin PF06309.6 EMR61973.1 - 0.051 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Torsin AAA_14 PF13173.1 EMR61973.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EMR61973.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PAM2 PF07145.10 EMR61975.1 - 0.0028 17.0 0.3 0.057 12.9 0.1 2.4 2 0 0 2 2 2 1 Ataxin-2 C-terminal region MFS_1 PF07690.11 EMR61976.1 - 6.5e-30 104.0 31.6 9.6e-30 103.4 18.8 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MMPL PF03176.10 EMR61976.1 - 0.44 9.1 4.5 0.14 10.8 0.5 2.0 2 0 0 2 2 2 0 MMPL family DUF87 PF01935.12 EMR61977.1 - 0.0002 21.2 0.0 0.63 9.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_10 PF12846.2 EMR61977.1 - 0.0015 18.0 0.0 0.0025 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain Arch_ATPase PF01637.13 EMR61977.1 - 0.0017 18.1 0.0 0.56 9.8 0.0 2.2 2 0 0 2 2 2 2 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EMR61977.1 - 0.045 13.2 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EMR61977.1 - 0.082 12.8 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EMR61977.1 - 0.091 12.8 0.0 0.67 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 EMR61978.1 - 7e-43 146.6 0.0 3.1e-42 144.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR61978.1 - 2.8e-30 105.2 0.0 4.4e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_S8 PF00082.17 EMR61978.1 - 1.4e-27 96.6 9.8 2.2e-27 95.9 6.8 1.3 1 0 0 1 1 1 1 Subtilase family Kdo PF06293.9 EMR61978.1 - 0.00097 18.2 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMR61978.1 - 0.1 11.5 0.0 0.29 10.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.20 EMR61979.1 - 3.6e-26 91.8 0.0 1.3e-25 90.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR61979.1 - 7.5e-07 28.4 0.0 0.0064 15.5 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EMR61979.1 - 0.0053 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EMR61979.1 - 0.054 12.5 0.0 0.19 10.7 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RPE65 PF03055.10 EMR61981.1 - 1.5e-109 366.8 0.0 2.8e-59 200.9 0.0 2.0 1 1 1 2 2 2 2 Retinal pigment epithelial membrane protein PAD PF03068.10 EMR61982.1 - 8.1e-50 169.3 0.0 1.4e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Ank_5 PF13857.1 EMR61983.1 - 4.6e-05 23.5 0.4 0.0007 19.7 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMR61983.1 - 7e-05 23.0 0.0 0.00011 22.4 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMR61983.1 - 0.00092 18.9 0.0 0.0066 16.1 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EMR61983.1 - 0.0013 19.1 0.0 0.087 13.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR61983.1 - 0.078 13.2 0.6 0.34 11.3 0.0 2.5 3 1 0 3 3 3 0 Ankyrin repeat PSDC PF12588.3 EMR61984.1 - 1e-41 141.8 0.0 1.6e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EMR61984.1 - 2e-30 105.5 0.0 2.8e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_S8 PF00082.17 EMR61985.1 - 2.3e-09 36.8 0.0 3.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Glyco_hydro_61 PF03443.9 EMR61986.1 - 1.4e-45 155.7 0.0 1.6e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NACHT PF05729.7 EMR61987.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 EMR61987.1 - 2.9e-11 42.7 0.0 6.1e-11 41.7 0.0 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_14 PF13173.1 EMR61987.1 - 5.2e-06 26.3 0.0 0.00025 20.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR61987.1 - 1.6e-05 24.9 0.1 0.00015 21.7 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMR61987.1 - 2.2e-05 24.6 0.0 0.0001 22.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EMR61987.1 - 3.1e-05 24.1 0.0 0.00012 22.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EMR61987.1 - 9.3e-05 22.2 0.0 0.017 14.8 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase NB-ARC PF00931.17 EMR61987.1 - 0.00015 20.7 0.0 0.00028 19.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 EMR61987.1 - 0.0083 16.2 0.2 0.037 14.1 0.0 2.3 2 1 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 EMR61987.1 - 0.013 15.3 0.0 0.038 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMR61987.1 - 0.037 13.1 0.1 0.2 10.7 0.0 2.1 2 1 0 2 2 2 0 KaiC PIG-S PF10510.4 EMR61988.1 - 1.6e-116 390.0 1.2 2e-116 389.7 0.8 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein AMP-binding PF00501.23 EMR61989.1 - 7.3e-70 235.4 0.0 1e-69 234.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMR61989.1 - 2.5e-11 44.3 0.1 6.8e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NmrA PF05368.8 EMR61990.1 - 1.5e-24 86.5 4.0 1.9e-24 86.2 2.7 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR61990.1 - 3.5e-18 66.2 1.5 4.7e-18 65.8 1.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EMR61990.1 - 1.8e-08 33.7 0.7 1.8e-08 33.7 0.5 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 EMR61990.1 - 6.3e-08 32.3 0.4 1.6e-07 30.9 0.2 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMR61990.1 - 6.9e-06 26.0 0.5 1.5e-05 24.9 0.3 1.7 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EMR61990.1 - 1.9e-05 23.5 0.3 7.2e-05 21.6 0.2 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.1 EMR61990.1 - 5.7e-05 23.3 1.0 0.00011 22.3 0.7 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EMR61990.1 - 0.00077 19.5 0.3 0.0014 18.7 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 EMR61990.1 - 0.0021 17.6 1.9 0.0024 17.4 0.3 1.8 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 EMR61990.1 - 0.0026 17.7 0.7 0.0049 16.8 0.2 1.6 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.12 EMR61990.1 - 0.0033 17.8 0.7 0.0085 16.4 0.5 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EMR61990.1 - 0.0064 16.3 0.6 0.013 15.3 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase THF_DHG_CYH_C PF02882.14 EMR61990.1 - 0.0077 15.3 2.1 0.018 14.1 0.7 2.2 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain XdhC_C PF13478.1 EMR61990.1 - 0.0084 16.4 0.1 0.015 15.6 0.1 1.3 1 0 0 1 1 1 1 XdhC Rossmann domain KR PF08659.5 EMR61990.1 - 0.012 15.2 1.3 0.048 13.3 0.9 2.1 1 1 0 1 1 1 0 KR domain DAO PF01266.19 EMR61990.1 - 0.026 13.4 0.1 0.042 12.7 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EMR61990.1 - 0.057 12.9 1.0 0.11 12.0 0.7 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 EMR61990.1 - 0.073 13.1 0.1 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EMR61990.1 - 0.12 11.5 0.2 0.22 10.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.10 EMR61990.1 - 0.22 11.1 2.8 0.12 11.9 0.4 1.6 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein DUF2236 PF09995.4 EMR61991.1 - 6.8e-05 22.2 2.9 0.00036 19.9 2.0 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Polysacc_synt_4 PF04669.8 EMR61992.1 - 2.3e-23 82.5 1.6 1.7e-22 79.7 1.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis Amidoligase_2 PF12224.3 EMR61993.1 - 1.9e-20 73.5 0.0 2.3e-16 60.1 0.0 2.6 2 1 0 2 2 2 2 Putative amidoligase enzyme Abi_2 PF07751.6 EMR61993.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Abi-like protein Ribosomal_L37e PF01907.14 EMR61993.1 - 0.12 12.1 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L37e p450 PF00067.17 EMR61994.1 - 1.4e-48 165.6 0.0 3.2e-48 164.4 0.0 1.5 1 1 1 2 2 2 1 Cytochrome P450 NUP PF06516.6 EMR61995.1 - 4.3e-101 337.8 0.0 5.4e-101 337.5 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Kelch_1 PF01344.20 EMR61996.1 - 3.5e-39 132.1 16.2 2.1e-09 36.7 0.1 7.1 7 1 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 EMR61996.1 - 9.3e-31 104.7 17.0 7.8e-08 32.1 0.0 7.2 3 2 4 7 7 7 6 Kelch motif Kelch_3 PF13415.1 EMR61996.1 - 1.1e-26 92.3 12.2 6e-08 32.6 0.3 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EMR61996.1 - 2.6e-16 59.0 27.5 0.0012 18.5 0.2 7.0 5 3 2 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EMR61996.1 - 8.9e-14 51.0 10.9 0.059 13.3 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EMR61996.1 - 7.9e-13 47.6 15.8 0.027 14.2 0.0 7.1 6 3 0 6 6 6 5 Kelch motif DUF3239 PF11580.3 EMR61996.1 - 0.17 11.9 0.2 4.1 7.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3239) PQQ_3 PF13570.1 EMR61996.1 - 0.87 9.9 20.6 2 8.8 4.4 4.8 4 1 1 5 5 5 0 PQQ-like domain 7TMR-DISM_7TM PF07695.6 EMR61997.1 - 0.017 14.8 8.3 0.1 12.2 3.1 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF3149 PF11346.3 EMR61997.1 - 0.12 11.9 7.0 0.2 11.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) DUF4384 PF14326.1 EMR61998.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) ABC_tran PF00005.22 EMR61999.1 - 1.2e-54 184.3 0.0 5.8e-26 91.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMR61999.1 - 6e-45 153.7 19.9 3.1e-30 105.5 9.4 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EMR61999.1 - 2.2e-13 49.9 0.1 1e-06 28.1 0.0 5.1 5 1 0 6 6 6 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMR61999.1 - 1.9e-12 47.7 0.4 0.0052 16.7 0.1 4.1 4 0 0 4 4 4 3 AAA domain DUF258 PF03193.11 EMR61999.1 - 4.8e-08 32.3 0.4 0.0036 16.4 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMR61999.1 - 1.5e-07 32.2 0.3 0.008 16.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EMR61999.1 - 1.6e-07 30.7 5.1 0.0006 19.2 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EMR61999.1 - 1.6e-07 31.4 0.1 0.03 14.4 0.1 3.8 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EMR61999.1 - 4e-06 26.9 2.6 0.031 14.2 0.2 3.3 4 0 0 4 4 3 2 AAA ATPase domain AAA_18 PF13238.1 EMR61999.1 - 1.7e-05 25.1 0.1 0.068 13.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 EMR61999.1 - 2.4e-05 23.1 0.0 1.3 7.4 0.0 4.6 5 0 0 5 5 5 1 Predicted ATPase of the ABC class AAA_10 PF12846.2 EMR61999.1 - 2.7e-05 23.7 2.3 0.087 12.2 0.1 2.9 2 0 0 2 2 2 2 AAA-like domain AAA_25 PF13481.1 EMR61999.1 - 9e-05 21.9 0.5 0.25 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EMR61999.1 - 0.00024 20.9 0.2 0.92 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EMR61999.1 - 0.00026 20.9 0.7 0.49 10.3 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 EMR61999.1 - 0.00031 21.1 0.6 0.06 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMR61999.1 - 0.00053 20.1 0.2 1.3 9.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.1 EMR61999.1 - 0.00066 19.5 0.0 1.4 8.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EMR61999.1 - 0.0011 18.1 0.0 0.081 12.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.9 EMR61999.1 - 0.0012 18.6 0.0 2.1 8.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Miro PF08477.8 EMR61999.1 - 0.0014 19.1 0.1 0.35 11.3 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 EMR61999.1 - 0.0019 17.9 0.5 1.3 8.6 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EMR61999.1 - 0.014 14.9 0.4 12 5.3 0.0 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family SbcCD_C PF13558.1 EMR61999.1 - 0.016 15.1 0.0 2.7 7.9 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 EMR61999.1 - 0.028 14.0 0.4 8.6 5.9 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AIG1 PF04548.11 EMR61999.1 - 0.029 13.4 0.2 0.092 11.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family DUF3987 PF13148.1 EMR61999.1 - 0.037 12.5 0.0 1 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF87 PF01935.12 EMR61999.1 - 0.044 13.5 2.2 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 Arch_ATPase PF01637.13 EMR61999.1 - 0.061 13.0 1.3 6.8 6.3 0.0 3.0 2 1 0 2 2 2 0 Archaeal ATPase Septin PF00735.13 EMR61999.1 - 0.064 12.2 0.0 11 4.8 0.0 2.3 2 0 0 2 2 2 0 Septin Mg_chelatase PF01078.16 EMR61999.1 - 0.13 11.4 0.2 0.82 8.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EMR61999.1 - 0.2 11.8 0.0 11 6.1 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EMR61999.1 - 0.23 10.9 0.0 4.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 EMR61999.1 - 0.5 9.1 0.3 20 3.9 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.10 EMR61999.1 - 0.62 8.6 0.1 1.1 7.8 0.1 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 EMR61999.1 - 1.6 8.3 2.9 9.2 5.7 0.2 2.2 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.7 EMR62000.1 - 0.17 10.4 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 COG5 PF10392.4 EMR62001.1 - 5.2e-38 129.9 3.0 7e-38 129.5 0.2 2.4 3 0 0 3 3 3 1 Golgi transport complex subunit 5 adh_short PF00106.20 EMR62002.1 - 3.9e-19 69.1 0.1 5.7e-19 68.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR62002.1 - 5.2e-11 42.5 0.1 8.9e-11 41.7 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR62002.1 - 4.4e-06 26.6 0.0 6.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR62002.1 - 0.00087 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR62002.1 - 0.011 15.6 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 EMR62002.1 - 0.056 13.5 0.1 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 EMR62002.1 - 0.058 13.1 0.3 0.15 11.9 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase tRNA-synt_1 PF00133.17 EMR62003.1 - 8.9e-39 132.9 0.0 6.8e-26 90.4 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EMR62003.1 - 9.7e-19 67.2 0.0 1.4e-09 37.0 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EMR62003.1 - 2.5e-13 50.0 0.1 5e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EMR62003.1 - 1e-08 34.7 0.0 1.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Tape_meas_lam_C PF09718.5 EMR62004.1 - 0.026 14.4 3.1 0.041 13.7 1.1 1.9 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) SseC PF04888.7 EMR62004.1 - 0.31 10.3 7.1 0.37 10.0 4.9 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family EspB PF05802.6 EMR62004.1 - 0.33 9.8 4.7 0.37 9.6 3.2 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein Synuclein PF01387.12 EMR62004.1 - 0.51 10.2 8.1 5.3 6.9 5.1 2.4 1 1 0 1 1 1 0 Synuclein Chlorosome_CsmC PF11098.3 EMR62004.1 - 4.9 6.8 15.3 7.6 6.2 10.6 1.4 1 1 0 1 1 1 0 Chlorosome envelope protein C Epimerase PF01370.16 EMR62005.1 - 3.8e-11 42.8 0.0 8.3e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR62005.1 - 2e-05 24.6 0.0 9.2e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMR62005.1 - 8.3e-05 22.5 0.0 0.00019 21.3 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EMR62005.1 - 0.0048 16.1 0.1 0.0095 15.2 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EMR62005.1 - 0.085 11.7 0.0 0.25 10.1 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.7 EMR62005.1 - 0.099 11.5 0.0 0.9 8.4 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Glyco_transf_20 PF00982.16 EMR62006.1 - 2.9e-148 494.2 0.0 4.5e-148 493.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EMR62006.1 - 2.4e-76 255.7 0.7 5e-76 254.6 0.0 1.9 3 0 0 3 3 3 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EMR62006.1 - 0.00027 20.5 0.0 0.054 13.0 0.0 2.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMR62006.1 - 0.0088 16.2 0.0 0.54 10.3 0.0 2.5 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase PPV_E1_N PF00524.13 EMR62006.1 - 0.027 14.6 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 E1 Protein, N terminal domain Glyco_trans_1_4 PF13692.1 EMR62006.1 - 0.12 12.4 0.0 0.52 10.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 MFS_1 PF07690.11 EMR62007.1 - 2.2e-12 46.3 9.4 4.6e-09 35.4 4.2 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3278 PF11683.3 EMR62007.1 - 0.33 10.9 0.0 0.33 10.9 0.0 2.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3278) FtsX PF02687.16 EMR62007.1 - 3.9 7.2 9.5 0.092 12.5 1.1 2.1 2 0 0 2 2 2 0 FtsX-like permease family Oxidored_FMN PF00724.15 EMR62010.1 - 2.1e-63 214.4 0.0 1.5e-62 211.5 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Clat_adaptor_s PF01217.15 EMR62011.1 - 1.4e-56 190.1 2.1 1.6e-56 189.9 1.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LCM PF04072.9 EMR62012.1 - 9e-23 80.7 0.0 1.8e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Lipase_GDSL_2 PF13472.1 EMR62012.1 - 7e-14 52.3 0.1 1.9e-13 50.9 0.1 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMR62012.1 - 6.2e-09 36.0 0.0 1.3e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EMR62012.1 - 0.0015 18.3 0.0 0.0063 16.2 0.0 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Fungal_trans PF04082.13 EMR62013.1 - 1.5e-07 30.5 0.0 0.00066 18.6 0.0 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR62013.1 - 0.00012 21.9 11.7 0.00023 21.0 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2421 PF10334.4 EMR62014.1 - 5.1e-06 26.2 0.0 7.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EMR62014.1 - 0.025 13.2 0.0 0.038 12.6 0.0 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Fructosamin_kin PF03881.9 EMR62015.1 - 1.8e-27 96.0 0.0 2.3e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EMR62015.1 - 0.014 15.1 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family GMC_oxred_N PF00732.14 EMR62016.1 - 1.3e-23 83.5 0.0 1e-16 60.9 0.0 3.1 3 0 0 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR62016.1 - 2.1e-23 83.2 0.0 3.4e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EMR62016.1 - 6.1e-06 26.1 0.1 1.4e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR62016.1 - 0.0004 19.3 0.0 0.00075 18.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 EMR62016.1 - 0.00045 19.6 0.0 0.00092 18.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 EMR62016.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR62016.1 - 0.0044 15.9 1.0 0.0065 15.3 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMR62016.1 - 0.0092 14.4 0.2 0.013 13.9 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EMR62016.1 - 0.0099 14.8 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMR62016.1 - 0.013 15.6 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMR62016.1 - 0.15 11.0 0.2 0.24 10.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EMR62016.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EMR62016.1 - 0.22 10.3 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TFIID-18kDa PF02269.11 EMR62017.1 - 3.6e-29 100.4 1.3 3.2e-28 97.3 0.1 2.5 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.13 EMR62017.1 - 0.021 13.9 1.5 0.041 13.0 1.1 1.4 1 0 0 1 1 1 0 Myc amino-terminal region SCHIP-1 PF10148.4 EMR62017.1 - 0.13 11.6 0.5 0.29 10.4 0.4 1.5 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Ist1 PF03398.9 EMR62019.1 - 5.3e-64 214.5 0.4 6.6e-64 214.2 0.3 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Pkinase PF00069.20 EMR62020.1 - 5.5e-13 48.6 0.0 2.4e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR62020.1 - 0.00033 19.7 0.0 0.014 14.4 0.0 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMR62020.1 - 0.00042 20.1 0.3 0.018 14.8 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Mito_fiss_reg PF05308.6 EMR62020.1 - 0.33 10.3 1.8 0.52 9.6 1.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator EB1 PF03271.12 EMR62021.1 - 5.3e-18 64.7 0.7 1.1e-17 63.8 0.5 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EMR62021.1 - 1.4e-06 28.2 1.0 2.4e-06 27.5 0.7 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain LMSTEN PF07988.7 EMR62021.1 - 0.042 13.1 0.9 0.15 11.3 0.3 2.0 2 0 0 2 2 2 0 LMSTEN motif Tyrosinase PF00264.15 EMR62022.1 - 4.2e-36 125.2 0.0 5.4e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase TPR_12 PF13424.1 EMR62023.1 - 1.7e-10 40.6 14.2 0.51 10.2 0.2 10.1 9 1 1 10 10 10 3 Tetratricopeptide repeat NACHT PF05729.7 EMR62023.1 - 2e-09 37.3 0.9 7.5e-09 35.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EMR62023.1 - 9.2e-06 25.8 0.0 5.7e-05 23.2 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR62023.1 - 3.2e-05 23.9 0.2 0.00014 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EMR62023.1 - 0.00018 22.2 0.1 0.0023 18.7 0.0 2.9 1 1 0 1 1 1 1 AAA domain TPR_2 PF07719.12 EMR62023.1 - 0.0056 16.5 8.3 2.3 8.3 0.4 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR62023.1 - 0.0062 16.8 1.0 0.038 14.3 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat AAA_33 PF13671.1 EMR62023.1 - 0.0086 15.9 0.1 0.1 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EMR62023.1 - 0.0096 16.1 0.1 0.055 13.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EMR62023.1 - 0.011 15.5 0.0 0.043 13.5 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EMR62023.1 - 0.032 14.5 0.1 0.37 11.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain Apc3 PF12895.2 EMR62023.1 - 0.034 14.2 17.8 0.058 13.5 0.2 6.3 8 0 0 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EMR62023.1 - 0.04 13.5 3.7 2.2 8.0 0.4 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Dendrin PF15498.1 EMR62023.1 - 0.29 9.6 2.4 0.43 9.0 1.7 1.1 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin Acetyltransf_3 PF13302.1 EMR62024.1 - 1.5e-15 57.6 0.0 2e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR62024.1 - 1.7e-05 24.7 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EMR62024.1 - 1.9e-05 24.6 0.0 3.2e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMR62024.1 - 0.0065 16.3 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain D123 PF07065.9 EMR62025.1 - 0.0017 17.4 0.0 0.022 13.8 0.0 2.0 1 1 0 1 1 1 1 D123 DnaJ PF00226.26 EMR62027.1 - 7.1e-18 64.1 0.1 1.4e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Vfa1 PF08432.5 EMR62027.1 - 1.3 8.9 13.1 0.29 11.1 6.6 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 UcrQ PF02939.11 EMR62028.1 - 2.7e-29 100.8 0.3 3.3e-29 100.5 0.2 1.1 1 0 0 1 1 1 1 UcrQ family RGS PF00615.14 EMR62029.1 - 5.3e-05 23.2 0.0 0.00029 20.9 0.0 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain MFS_3 PF05977.8 EMR62029.1 - 0.022 12.8 0.0 0.033 12.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector Mdv1 PF11542.3 EMR62029.1 - 0.11 12.4 0.1 0.39 10.6 0.0 2.0 1 0 0 1 1 1 0 Mitochondrial division protein 1 SNARE PF05739.14 EMR62030.1 - 1.9e-09 37.0 8.0 4.5e-09 35.8 5.5 1.7 1 0 0 1 1 1 1 SNARE domain DUF3499 PF12005.3 EMR62030.1 - 0.12 12.4 1.5 8.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) BLOC1_2 PF10046.4 EMR62030.1 - 1.5 9.0 6.0 1 9.5 2.4 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF745 PF05335.8 EMR62030.1 - 3.9 6.9 8.7 0.46 9.9 1.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF745) p450 PF00067.17 EMR62031.1 - 3.1e-45 154.5 0.0 3.8e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EMR62032.1 - 2.2e-09 36.8 0.4 3.6e-08 32.9 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF2415 PF10313.4 EMR62032.1 - 0.00018 21.1 0.1 0.021 14.4 0.0 2.8 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) Cytochrom_D1 PF02239.11 EMR62032.1 - 0.0021 16.4 0.0 0.017 13.4 0.0 2.1 1 1 1 2 2 2 1 Cytochrome D1 heme domain TFIIIC_delta PF12657.2 EMR62032.1 - 0.0039 16.9 0.0 0.0068 16.1 0.0 1.3 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term PQQ_2 PF13360.1 EMR62032.1 - 0.018 14.5 0.0 0.58 9.5 0.0 2.4 1 1 1 2 2 2 0 PQQ-like domain Chitin_synth_2 PF03142.10 EMR62033.1 - 2.6e-290 963.3 0.1 3.4e-290 962.9 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EMR62033.1 - 2.8e-17 63.0 5.9 1.3e-16 60.8 3.1 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMR62033.1 - 4.7e-14 52.7 0.0 2.1e-12 47.3 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EMR62033.1 - 1e-12 47.6 0.1 3.4e-10 39.5 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EMR62033.1 - 0.00038 19.7 0.0 0.0038 16.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 DASH_Dad4 PF08650.5 EMR62034.1 - 1.8e-25 88.6 7.9 2.1e-25 88.3 5.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.12 EMR62034.1 - 0.13 12.1 0.5 0.16 11.9 0.3 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor DASH_Dad1 PF08649.5 EMR62034.1 - 0.44 10.2 3.4 0.66 9.7 2.3 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad1 TPR_MLP1_2 PF07926.7 EMR62034.1 - 0.53 10.0 4.6 4 7.2 1.5 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Got1 PF04178.7 EMR62035.1 - 4.2e-19 68.7 11.0 4.8e-19 68.6 7.6 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 EMR62035.1 - 1.8 8.3 10.2 0.19 11.4 2.8 2.2 2 0 0 2 2 2 0 YrhK-like protein Profilin PF00235.14 EMR62036.1 - 3.4e-39 133.6 1.1 3.8e-39 133.5 0.7 1.0 1 0 0 1 1 1 1 Profilin Macoilin PF09726.4 EMR62037.1 - 2.2 6.4 11.7 2.2 6.4 8.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Actin PF00022.14 EMR62038.1 - 1.6e-31 109.1 0.0 2.1e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Actin V_ATPase_I PF01496.14 EMR62038.1 - 0.81 7.4 2.9 1.1 7.0 2.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YL1_C PF08265.6 EMR62039.1 - 6.6e-15 54.3 0.1 9.9e-15 53.8 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF1751 PF08551.5 EMR62040.1 - 3.4e-28 97.8 4.2 7.5e-28 96.7 2.9 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EMR62040.1 - 0.12 12.3 10.1 0.3 11.1 7.0 1.6 1 1 0 1 1 1 0 Rhomboid family RseC_MucC PF04246.7 EMR62040.1 - 0.93 9.0 5.8 2.4 7.7 0.2 2.6 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF4366 PF14283.1 EMR62042.1 - 0.0061 16.0 2.9 1 8.7 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4366) TUG-UBL1 PF11470.3 EMR62043.1 - 1e-23 83.0 0.2 1.9e-23 82.1 0.1 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 EMR62043.1 - 8.7e-05 22.5 0.0 0.00044 20.2 0.0 2.1 2 0 0 2 2 2 1 UBX domain Rad60-SLD PF11976.3 EMR62043.1 - 0.00058 19.5 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF605 PF04652.11 EMR62043.1 - 0.071 12.4 12.3 0.092 12.1 8.5 1.2 1 0 0 1 1 1 0 Vta1 like RBD PF02196.10 EMR62043.1 - 0.085 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain bZIP_C PF12498.3 EMR62043.1 - 0.35 12.1 12.2 0.13 13.5 1.2 2.4 1 1 1 2 2 2 0 Basic leucine-zipper C terminal AMP-binding PF00501.23 EMR62044.1 - 4e-88 295.6 0.0 4.7e-88 295.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMR62044.1 - 3.6e-11 43.8 0.0 6.6e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 EMR62045.1 - 5.4e-66 222.3 0.0 7.6e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR62045.1 - 5.9e-42 143.5 0.0 8.6e-42 142.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR62045.1 - 5.6e-09 35.3 0.0 1.4e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like POLO_box PF00659.13 EMR62045.1 - 1.1e-07 31.6 0.0 0.00039 20.3 0.0 3.0 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 EMR62045.1 - 0.002 17.2 0.0 0.0037 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Suf PF05843.9 EMR62046.1 - 8.5e-07 28.9 5.1 0.00083 19.1 0.0 3.4 3 0 0 3 3 3 3 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EMR62046.1 - 2.4e-06 28.0 0.0 0.0002 21.9 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMR62046.1 - 0.00017 21.9 3.9 2.9 8.7 0.0 6.2 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR62046.1 - 0.093 13.0 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_17 PF00332.13 EMR62047.1 - 3.7e-05 22.9 0.0 0.00021 20.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 RNB PF00773.14 EMR62048.1 - 1.6e-56 191.9 0.0 2.2e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 RNB domain SR-25 PF10500.4 EMR62048.1 - 0.19 11.2 2.9 0.34 10.3 2.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ras PF00071.17 EMR62049.1 - 2.4e-49 166.8 0.0 2.9e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR62049.1 - 2e-15 57.3 0.0 4.1e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMR62049.1 - 6.3e-11 41.8 0.0 8.9e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EMR62049.1 - 0.00034 20.7 0.2 0.003 17.6 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EMR62049.1 - 0.0019 17.3 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 EMR62049.1 - 0.025 13.9 0.1 0.043 13.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 EMR62049.1 - 0.046 12.3 2.4 0.77 8.3 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 EMR62049.1 - 0.053 13.6 0.3 0.2 11.7 0.1 2.1 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.5 EMR62049.1 - 0.063 12.4 0.0 0.11 11.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 EMR62049.1 - 0.063 13.1 0.1 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EMR62049.1 - 0.098 12.6 0.3 0.41 10.6 0.1 1.9 1 1 1 2 2 2 0 50S ribosome-binding GTPase Proteasome PF00227.21 EMR62050.1 - 4.8e-41 140.1 0.0 5.6e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit AAA PF00004.24 EMR62051.1 - 8.1e-46 155.5 0.0 1.3e-43 148.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EMR62051.1 - 1.3e-05 24.6 0.2 0.00013 21.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMR62051.1 - 5.5e-05 23.9 0.0 0.00015 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMR62051.1 - 5.7e-05 22.2 0.0 0.00018 20.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMR62051.1 - 0.00011 22.3 0.0 0.0016 18.5 0.0 2.6 2 1 1 3 3 3 1 AAA domain Parvo_NS1 PF01057.12 EMR62051.1 - 0.00021 20.2 0.0 0.00039 19.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 EMR62051.1 - 0.0003 20.8 5.5 0.0094 15.9 0.0 3.8 3 1 0 4 4 4 1 AAA ATPase domain IstB_IS21 PF01695.12 EMR62051.1 - 0.0004 19.8 0.0 0.00084 18.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EMR62051.1 - 0.00064 19.6 0.0 0.0023 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EMR62051.1 - 0.0012 18.5 0.0 0.0059 16.3 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EMR62051.1 - 0.0013 17.9 1.0 0.017 14.3 0.0 2.8 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EMR62051.1 - 0.0028 17.7 0.0 0.011 15.9 0.0 2.1 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 EMR62051.1 - 0.0036 16.0 0.0 0.0053 15.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EMR62051.1 - 0.0048 16.6 0.0 0.028 14.1 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) KaiC PF06745.8 EMR62051.1 - 0.011 14.8 0.0 0.027 13.6 0.0 1.5 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 EMR62051.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 EMR62051.1 - 0.015 14.8 2.3 0.11 12.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EMR62051.1 - 0.016 15.1 0.1 0.049 13.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 EMR62051.1 - 0.017 15.0 0.0 0.083 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EMR62051.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMR62051.1 - 0.027 14.7 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EMR62051.1 - 0.036 13.0 0.0 0.063 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PPV_E1_C PF00519.12 EMR62051.1 - 0.11 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Sel1 PF08238.7 EMR62052.1 - 1.7e-38 130.1 33.0 2.4e-07 31.1 0.4 7.6 8 0 0 8 8 8 7 Sel1 repeat TPR_11 PF13414.1 EMR62052.1 - 0.036 13.7 3.6 2 8.1 0.2 3.2 3 1 0 3 3 3 0 TPR repeat SBDS PF01172.13 EMR62053.1 - 8.7e-25 86.3 0.7 1.1e-24 86.0 0.5 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 EMR62053.1 - 0.034 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Phage XkdN-like protein ATP11 PF06644.6 EMR62054.1 - 8.3e-75 251.7 0.0 9.7e-75 251.4 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Rotamase_2 PF13145.1 EMR62054.1 - 0.018 15.6 0.8 0.039 14.5 0.5 1.5 1 0 0 1 1 1 0 PPIC-type PPIASE domain peroxidase PF00141.18 EMR62055.1 - 7.1e-48 163.0 0.0 1.3e-47 162.2 0.0 1.4 1 0 0 1 1 1 1 Peroxidase DUF4366 PF14283.1 EMR62055.1 - 0.05 13.0 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) E1-E2_ATPase PF00122.15 EMR62057.1 - 4.3e-63 212.4 6.6 1.1e-62 211.1 3.9 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMR62057.1 - 7e-47 159.3 4.3 1.5e-46 158.2 2.9 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMR62057.1 - 3.1e-32 112.7 0.0 5.5e-31 108.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMR62057.1 - 1.8e-23 82.2 0.0 3.5e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMR62057.1 - 1.9e-18 65.6 0.0 4.4e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMR62057.1 - 6.1e-17 62.4 0.1 2e-16 60.6 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMR62057.1 - 5.8e-09 35.9 1.4 1.2e-06 28.2 1.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMR62057.1 - 0.11 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase OPA3 PF07047.7 EMR62058.1 - 2.5e-40 137.3 2.0 4.9e-40 136.4 1.4 1.5 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) IncA PF04156.9 EMR62058.1 - 0.0046 16.5 0.3 0.0046 16.5 0.2 1.6 2 0 0 2 2 2 1 IncA protein Spore_YpjB PF09577.5 EMR62058.1 - 0.1 12.1 0.7 5.4 6.5 0.0 2.0 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) DUF607 PF04678.8 EMR62058.1 - 0.13 12.2 1.0 2.9 7.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Tropomyosin PF00261.15 EMR62058.1 - 0.22 10.5 11.1 0.04 12.9 1.5 2.1 2 0 0 2 2 2 0 Tropomyosin HOOK PF05622.7 EMR62058.1 - 0.31 8.8 7.4 0.017 12.9 1.3 1.5 2 0 0 2 2 2 0 HOOK protein FemAB PF02388.11 EMR62058.1 - 0.71 8.4 6.0 0.42 9.2 0.2 2.0 2 0 0 2 2 2 0 FemAB family DUF3552 PF12072.3 EMR62058.1 - 5 6.2 13.8 1.2 8.3 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF4140 PF13600.1 EMR62058.1 - 6.7 7.2 8.6 0.43 11.0 0.9 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) XhlA PF10779.4 EMR62058.1 - 8.1 6.4 7.0 0.75 9.7 0.5 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Syja_N PF02383.13 EMR62059.1 - 6.3e-65 219.0 0.0 8.5e-55 185.7 0.0 2.6 1 1 1 2 2 2 2 SacI homology domain Exo_endo_phos PF03372.18 EMR62059.1 - 0.00032 20.7 0.0 0.32 10.8 0.0 2.4 1 1 1 2 2 2 2 Endonuclease/Exonuclease/phosphatase family SH3BGR PF04908.10 EMR62060.1 - 0.0032 17.3 0.0 0.0032 17.3 0.0 3.0 3 1 0 3 3 3 1 SH3-binding, glutamic acid-rich protein 14-3-3 PF00244.15 EMR62061.1 - 3.9e-114 379.6 1.9 4.9e-114 379.2 1.3 1.1 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 EMR62061.1 - 0.013 15.3 0.2 7.3 6.6 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat HisKA PF00512.20 EMR62061.1 - 0.09 12.7 1.7 19 5.3 0.0 3.3 4 0 0 4 4 4 0 His Kinase A (phospho-acceptor) domain MCM_N PF14551.1 EMR62061.1 - 0.77 10.2 4.0 25 5.3 2.8 2.3 1 1 0 1 1 1 0 MCM N-terminal domain Ribosomal_L36e PF01158.13 EMR62062.1 - 2.6e-38 129.9 4.8 2.9e-38 129.7 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EMR62062.1 - 0.0026 16.8 0.2 0.003 16.6 0.1 1.1 1 0 0 1 1 1 1 LemA family INT_SG_DDX_CT_C PF15300.1 EMR62062.1 - 0.082 12.3 0.4 0.37 10.2 0.0 2.0 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Herpes_TAF50 PF03326.8 EMR62063.1 - 0.88 8.4 7.9 1 8.2 5.5 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF605 PF04652.11 EMR62063.1 - 8.3 5.6 8.3 9.8 5.4 5.8 1.0 1 0 0 1 1 1 0 Vta1 like PDZ_2 PF13180.1 EMR62064.1 - 0.0012 18.6 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EMR62064.1 - 0.0025 17.9 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Dynactin_p22 PF07426.6 EMR62064.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 MAD PF05557.8 EMR62064.1 - 0.14 10.2 0.0 0.19 9.8 0.0 1.3 1 1 0 1 1 1 0 Mitotic checkpoint protein ELO PF01151.13 EMR62065.1 - 2e-78 263.1 8.9 2.4e-78 262.9 6.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4636 PF15468.1 EMR62065.1 - 0.0088 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4636) GMC_oxred_N PF00732.14 EMR62066.1 - 5.2e-31 107.8 2.2 6.4e-31 107.6 0.2 1.9 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR62066.1 - 7.2e-23 81.4 1.8 2.3e-21 76.6 0.0 2.8 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EMR62066.1 - 4.2e-07 29.1 1.0 1.6e-05 23.9 0.3 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR62066.1 - 1.1e-06 27.7 0.5 2e-06 26.9 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMR62066.1 - 3.8e-06 26.9 0.1 6.4e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMR62066.1 - 2.9e-05 23.2 0.9 4.9e-05 22.5 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMR62066.1 - 4e-05 23.5 1.3 4e-05 23.5 0.9 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMR62066.1 - 4.5e-05 22.6 0.3 0.00012 21.3 0.2 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EMR62066.1 - 0.0023 16.4 1.6 0.0037 15.7 0.3 1.9 3 0 0 3 3 3 1 HI0933-like protein 3HCDH_N PF02737.13 EMR62066.1 - 0.0068 16.0 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EMR62066.1 - 0.022 15.1 0.1 0.051 13.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Myc_N PF01056.13 EMR62066.1 - 0.041 13.0 1.3 0.065 12.3 0.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region FAD_oxidored PF12831.2 EMR62066.1 - 0.07 12.1 1.9 0.13 11.2 1.3 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EMR62066.1 - 0.09 12.1 3.4 0.14 11.5 2.3 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain LRR_6 PF13516.1 EMR62067.1 - 0.07 13.2 5.2 0.084 12.9 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeat DUF155 PF02582.9 EMR62069.1 - 1.1e-55 188.2 0.2 1.7e-55 187.6 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ADH_N PF08240.7 EMR62070.1 - 4.5e-08 32.8 0.0 8.1e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fungal_trans_2 PF11951.3 EMR62072.1 - 0.00023 19.8 0.2 0.00029 19.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 EMR62073.1 - 2.1e-12 46.8 1.7 1.7e-06 27.3 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 EMR62073.1 - 1.7e-05 23.8 0.3 3.2e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR62073.1 - 5.4e-05 22.2 0.1 0.00053 19.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR62073.1 - 0.00025 21.0 0.4 0.00097 19.1 0.3 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMR62073.1 - 0.0019 17.3 0.1 0.0042 16.2 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR62073.1 - 0.008 14.6 0.1 0.014 13.9 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EMR62073.1 - 0.0088 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR62073.1 - 0.034 13.2 0.9 0.43 9.6 0.1 2.4 3 0 0 3 3 3 0 Thi4 family Lycopene_cycl PF05834.7 EMR62073.1 - 0.16 10.8 2.0 3.3 6.5 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein SUR7 PF06687.7 EMR62074.1 - 0.0027 17.3 15.7 0.005 16.4 10.9 1.4 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EMR62074.1 - 0.61 9.7 19.0 0.15 11.6 7.3 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction RDD PF06271.7 EMR62074.1 - 0.61 9.9 5.4 1 9.2 0.8 2.3 2 1 0 2 2 2 0 RDD family GFO_IDH_MocA PF01408.17 EMR62075.1 - 2.8e-16 60.1 0.0 5.8e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMR62075.1 - 2.7e-05 23.9 0.0 7.9e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Whib PF02467.11 EMR62075.1 - 0.072 13.3 0.1 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 Transcription factor WhiB Peptidase_M10 PF00413.19 EMR62077.1 - 1.5e-08 34.5 2.3 1.8e-07 30.9 1.4 2.4 2 1 0 2 2 2 1 Matrixin Astacin PF01400.19 EMR62077.1 - 2.2e-06 27.2 0.0 4.5e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.1 EMR62077.1 - 3.6e-05 23.3 0.0 5.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMR62077.1 - 0.0017 18.4 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EMR62077.1 - 0.011 16.2 0.6 0.033 14.7 0.2 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMR62077.1 - 0.02 14.8 0.1 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Erv26 PF04148.8 EMR62080.1 - 2.4e-86 288.4 2.1 2.8e-86 288.2 1.4 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3377 PF11857.3 EMR62080.1 - 0.0015 18.1 0.0 0.0047 16.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) Cytochrom_C_asm PF01578.15 EMR62080.1 - 0.0016 18.0 0.1 0.0016 18.0 0.0 1.8 2 1 0 2 2 2 1 Cytochrome C assembly protein DUF996 PF06195.8 EMR62080.1 - 0.0034 17.3 1.8 0.0054 16.7 1.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF996) SprT-like PF10263.4 EMR62081.1 - 3.9e-06 26.6 0.0 7.7e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 SprT-like family DUF1996 PF09362.5 EMR62083.1 - 7.9e-89 297.3 0.6 1e-88 297.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Aldo_ket_red PF00248.16 EMR62084.1 - 1.3e-47 161.9 0.0 1.7e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ABC_tran PF00005.22 EMR62085.1 - 2.8e-51 173.3 0.1 2.2e-27 96.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMR62085.1 - 1e-23 84.7 0.0 1.2e-05 25.4 0.0 4.5 3 1 0 4 4 4 4 AAA domain ABC2_membrane_3 PF12698.2 EMR62085.1 - 5.8e-17 61.7 23.7 5.8e-17 61.7 16.4 2.4 2 0 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.14 EMR62085.1 - 5.4e-08 32.3 0.1 1 8.5 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMR62085.1 - 2.5e-07 31.2 0.1 0.014 15.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EMR62085.1 - 2e-06 27.2 1.1 0.023 14.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMR62085.1 - 1e-05 24.7 0.0 0.01 15.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMR62085.1 - 2.1e-05 24.6 0.2 0.12 12.3 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EMR62085.1 - 2.2e-05 24.5 0.0 0.32 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.10 EMR62085.1 - 3.8e-05 22.5 0.1 0.055 12.1 0.1 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein SRP54 PF00448.17 EMR62085.1 - 0.00018 20.9 0.3 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EMR62085.1 - 0.0013 18.3 0.3 0.84 9.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EMR62085.1 - 0.0014 18.5 0.1 1.8 8.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EMR62085.1 - 0.0022 17.1 0.1 1.3 8.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_10 PF12846.2 EMR62085.1 - 0.0022 17.4 0.0 2.1 7.6 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_19 PF13245.1 EMR62085.1 - 0.0028 17.3 6.3 0.67 9.7 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain ABC2_membrane_4 PF12730.2 EMR62085.1 - 0.0044 16.2 44.7 0.011 14.8 16.7 3.8 3 2 0 3 3 3 2 ABC-2 family transporter protein AAA_14 PF13173.1 EMR62085.1 - 0.0057 16.5 0.0 4.2 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EMR62085.1 - 0.007 15.9 0.9 1.3 8.6 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EMR62085.1 - 0.0076 15.9 0.0 5 6.7 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase AAA PF00004.24 EMR62085.1 - 0.0088 16.2 1.4 5.8 7.1 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EMR62085.1 - 0.015 14.9 0.5 2.3 7.8 0.1 2.8 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EMR62085.1 - 0.021 15.0 0.0 2.4 8.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.12 EMR62085.1 - 0.021 14.2 0.6 17 4.8 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_PrkA PF08298.6 EMR62085.1 - 0.022 13.4 0.0 3 6.4 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain AAA_24 PF13479.1 EMR62085.1 - 0.023 14.2 0.2 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EMR62085.1 - 0.024 14.6 1.4 4.1 7.3 0.2 3.0 4 0 0 4 4 2 0 AAA domain AAA_25 PF13481.1 EMR62085.1 - 0.033 13.6 0.4 10 5.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF2305 PF10230.4 EMR62085.1 - 0.037 13.4 0.0 0.091 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) AAA_15 PF13175.1 EMR62085.1 - 0.069 12.1 0.0 17 4.3 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain MobB PF03205.9 EMR62085.1 - 0.073 12.7 0.1 7.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EMR62085.1 - 0.1 13.4 0.1 13 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EMR62085.1 - 0.15 10.8 0.1 7.7 5.2 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain T2SE PF00437.15 EMR62085.1 - 0.16 10.8 0.5 3.3 6.5 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 EMR62085.1 - 0.2 11.1 0.8 12 5.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.1 EMR62085.1 - 0.3 9.5 0.1 6.2 5.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EMR62085.1 - 0.67 8.5 0.1 5.4 5.5 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit DUF3602 PF12223.3 EMR62086.1 - 2.2e-13 50.3 14.2 1.5e-12 47.7 4.4 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) WBS_methylT PF12589.3 EMR62087.1 - 5.7e-18 65.1 4.2 1.1e-17 64.2 2.9 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EMR62087.1 - 2.8e-10 40.5 0.0 5.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR62087.1 - 3.2e-07 30.6 0.0 7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR62087.1 - 1.1e-05 25.0 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR62087.1 - 0.00014 22.3 0.0 0.00037 20.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR62087.1 - 0.00028 21.4 0.1 0.00051 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMR62087.1 - 0.00039 20.0 0.0 0.00072 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EMR62087.1 - 0.00043 20.0 0.0 0.00064 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMR62087.1 - 0.0048 16.0 0.0 0.011 14.8 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EMR62087.1 - 0.0083 16.1 0.2 0.018 15.0 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain AAA_16 PF13191.1 EMR62088.1 - 0.00067 19.6 0.0 0.00096 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EMR62088.1 - 0.00096 19.3 0.2 0.0028 17.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMR62088.1 - 0.007 17.1 0.7 0.023 15.4 0.2 2.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMR62088.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EMR62088.1 - 0.016 15.3 0.1 0.029 14.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EMR62088.1 - 0.024 13.7 0.5 0.26 10.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 EMR62088.1 - 0.036 14.3 0.2 0.13 12.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EMR62088.1 - 0.042 12.9 0.2 0.075 12.1 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.6 EMR62088.1 - 0.046 13.6 0.4 0.19 11.5 0.1 2.0 2 1 0 2 2 2 0 Torsin AAA_24 PF13479.1 EMR62088.1 - 0.059 12.9 0.3 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMR62088.1 - 0.066 12.9 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 EMR62088.1 - 0.085 12.4 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EMR62088.1 - 0.12 11.9 0.5 0.41 10.1 0.1 2.1 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EMR62088.1 - 0.18 10.7 1.5 0.92 8.4 1.0 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EMR62088.1 - 0.29 10.5 2.3 0.23 10.8 0.4 1.6 2 0 0 2 2 2 0 AAA domain DUF1524 PF07510.6 EMR62090.1 - 4.4e-14 52.5 0.0 5.2e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) DEC-1_N PF04625.8 EMR62090.1 - 0.78 8.3 3.0 1.1 7.8 2.1 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region MFS_1 PF07690.11 EMR62091.1 - 2.9e-26 92.0 23.3 4.6e-26 91.3 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DWNN PF08783.6 EMR62092.1 - 0.14 12.0 0.4 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 DWNN domain DEAD PF00270.24 EMR62093.1 - 1.5e-13 50.5 0.0 1.8e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EMR62093.1 - 6.9e-12 45.5 0.0 9.5e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMR62093.1 - 0.046 12.5 0.0 0.052 12.3 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF2075 PF09848.4 EMR62093.1 - 0.13 11.1 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Exonuc_VII_L PF02601.10 EMR62094.1 - 0.0008 18.6 1.4 0.00083 18.6 1.0 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit IncA PF04156.9 EMR62094.1 - 0.0019 17.8 2.0 0.0023 17.5 1.4 1.2 1 0 0 1 1 1 1 IncA protein Clp1 PF06807.9 EMR62094.1 - 0.067 12.9 0.2 0.085 12.6 0.2 1.1 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 KfrA_N PF11740.3 EMR62094.1 - 0.15 12.4 7.6 0.3 11.5 5.3 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term bZIP_Maf PF03131.12 EMR62095.1 - 0.093 13.0 2.5 0.26 11.5 1.8 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor Phage_HK97_TLTM PF06120.6 EMR62096.1 - 0.00016 21.1 5.0 0.00019 20.8 3.5 1.0 1 0 0 1 1 1 1 Tail length tape measure protein CALCOCO1 PF07888.6 EMR62096.1 - 0.0077 14.5 3.3 0.0092 14.3 2.3 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.9 EMR62096.1 - 0.028 14.0 0.2 0.036 13.6 0.2 1.2 1 0 0 1 1 1 0 IncA protein LXG PF04740.7 EMR62096.1 - 0.039 13.7 0.9 0.08 12.7 0.7 1.5 1 1 0 1 1 1 0 LXG domain of WXG superfamily GIDA_assoc_3 PF13932.1 EMR62096.1 - 0.048 13.7 0.8 3.5 7.7 0.1 2.3 1 1 1 2 2 2 0 GidA associated domain 3 HsbA PF12296.3 EMR62096.1 - 0.059 13.2 0.6 0.62 9.9 0.0 2.0 1 1 1 2 2 2 0 Hydrophobic surface binding protein A GvpK PF05121.7 EMR62096.1 - 0.059 13.1 2.5 0.58 10.0 0.6 2.3 1 1 1 2 2 2 0 Gas vesicle protein K V-SNARE PF05008.10 EMR62096.1 - 0.087 13.0 1.5 0.16 12.1 0.2 2.0 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Syntaxin-6_N PF09177.6 EMR62096.1 - 0.12 12.8 1.8 0.88 10.0 1.2 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal MSC PF09402.5 EMR62097.1 - 1.4e-96 323.1 0.0 1.8e-96 322.7 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EMR62097.1 - 6.9e-16 57.5 0.1 1.3e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain Ashwin PF15323.1 EMR62097.1 - 0.084 12.8 2.6 0.27 11.1 1.8 1.9 1 0 0 1 1 1 0 Developmental protein SAP PF02037.22 EMR62097.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 SAP domain RRM_1 PF00076.17 EMR62098.1 - 1.2e-39 133.7 0.3 3.2e-19 68.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR62098.1 - 1.4e-28 98.6 0.0 1.5e-13 50.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR62098.1 - 7.5e-11 41.7 0.0 0.00044 20.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDUFB10 PF10249.4 EMR62099.1 - 0.0005 20.2 0.2 0.00055 20.0 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.9 EMR62099.1 - 0.051 14.0 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase TAP_C PF03943.8 EMR62100.1 - 1.8e-13 49.6 0.3 3.3e-13 48.8 0.2 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EMR62100.1 - 6.8e-05 22.3 7.1 0.0013 18.3 0.2 2.6 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 EMR62100.1 - 0.0041 17.4 0.0 0.013 15.8 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Amidoligase_2 PF12224.3 EMR62101.1 - 1.2e-09 38.1 0.0 1.4e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 Putative amidoligase enzyme MRC1 PF09444.5 EMR62101.1 - 0.0027 18.0 1.6 0.45 10.8 0.0 2.5 2 0 0 2 2 2 2 MRC1-like domain DUF3439 PF11921.3 EMR62101.1 - 0.075 12.7 1.9 0.13 11.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) GST_N PF02798.15 EMR62102.1 - 2.6e-17 62.7 0.0 5.2e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMR62102.1 - 4.3e-16 58.6 0.0 9.1e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMR62102.1 - 2.7e-14 53.1 0.0 5.5e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR62102.1 - 6.6e-14 51.6 0.0 2.6e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMR62102.1 - 1.2e-07 31.5 0.0 2.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR62102.1 - 1.3e-05 25.5 0.1 2.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EMR62102.1 - 0.022 15.1 0.0 0.036 14.4 0.0 1.3 1 0 0 1 1 1 0 MetRS-N binding domain Pyr_redox_3 PF13738.1 EMR62103.1 - 4.5e-19 69.3 0.0 1e-18 68.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR62103.1 - 6.8e-18 64.1 0.0 1.5e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMR62103.1 - 2e-07 30.9 0.0 5.9e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EMR62103.1 - 8.6e-06 24.8 0.0 0.0011 17.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EMR62103.1 - 0.0024 17.9 0.0 0.52 10.4 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EMR62103.1 - 0.0076 16.1 0.0 0.22 11.3 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR62103.1 - 0.065 13.0 0.1 3.5 7.3 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding MFS_1 PF07690.11 EMR62104.1 - 1.1e-31 109.8 22.9 1.2e-31 109.7 15.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.1 EMR62105.1 - 6.5e-28 98.1 0.0 8.1e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR62105.1 - 2.5e-23 82.7 0.2 3.5e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR62105.1 - 1.1e-10 41.4 0.1 2e-10 40.5 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR62105.1 - 5.1e-05 22.8 0.2 9.3e-05 21.9 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AAA_17 PF13207.1 EMR62106.1 - 8e-07 29.9 0.1 3.3e-06 27.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMR62106.1 - 0.00023 21.4 0.0 0.001 19.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 EMR62106.1 - 0.00036 20.0 0.0 0.00051 19.5 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain NACHT PF05729.7 EMR62106.1 - 0.00046 19.8 0.0 0.00077 19.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMR62106.1 - 0.00048 20.1 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ArgK PF03308.11 EMR62106.1 - 0.0014 17.5 0.0 0.0022 16.7 0.0 1.3 1 0 0 1 1 1 1 ArgK protein PRK PF00485.13 EMR62106.1 - 0.0027 17.2 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.9 EMR62106.1 - 0.004 16.1 0.0 0.0046 15.9 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_19 PF13245.1 EMR62106.1 - 0.0058 16.3 0.1 3.7 7.3 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EMR62106.1 - 0.0064 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EMR62106.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 EMR62106.1 - 0.014 15.5 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EMR62106.1 - 0.017 15.4 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EMR62106.1 - 0.019 14.8 0.0 0.051 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EMR62106.1 - 0.026 14.1 0.1 0.09 12.4 0.1 1.8 1 1 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 EMR62106.1 - 0.029 14.1 0.0 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ArsA_ATPase PF02374.10 EMR62106.1 - 0.044 12.8 0.1 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase Zeta_toxin PF06414.7 EMR62106.1 - 0.048 12.7 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 EMR62106.1 - 0.054 12.3 0.0 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 EMR62106.1 - 0.059 13.0 0.2 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 NTPase IstB_IS21 PF01695.12 EMR62106.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_29 PF13555.1 EMR62106.1 - 0.092 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EMR62106.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF35_N PF12172.3 EMR62107.1 - 0.093 12.6 1.5 0.2 11.6 1.0 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) KH_1 PF00013.24 EMR62109.1 - 9.8e-42 140.4 13.1 1.2e-14 53.6 0.9 3.5 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EMR62109.1 - 2e-29 100.7 19.0 1.3e-10 40.7 1.1 4.3 5 0 0 5 5 5 3 KH domain KH_2 PF07650.12 EMR62109.1 - 3.2e-13 49.0 2.6 0.0035 16.8 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EMR62109.1 - 1.1e-08 34.5 4.3 0.052 13.1 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EMR62109.1 - 5.6e-06 26.0 1.9 0.85 9.4 0.0 3.7 4 0 0 4 4 4 3 NusA-like KH domain Homeobox PF00046.24 EMR62110.1 - 4.9e-20 70.9 4.8 9.2e-20 70.0 3.3 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EMR62110.1 - 0.00013 21.6 0.6 0.00039 20.0 0.4 1.9 1 0 0 1 1 1 1 Homeobox KN domain SPX PF03105.14 EMR62111.1 - 1.6e-05 24.8 5.7 2e-05 24.4 4.0 1.1 1 0 0 1 1 1 1 SPX domain HHV6-IE PF03753.8 EMR62111.1 - 0.02 12.4 7.4 0.025 12.0 5.2 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein CCDC32 PF14989.1 EMR62111.1 - 1.2 8.9 9.2 1.1 9.0 4.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing 32 DUF4187 PF13821.1 EMR62112.1 - 1.5e-18 66.1 2.1 4.6e-18 64.5 1.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EMR62112.1 - 3.7e-07 29.8 1.0 0.00022 20.9 0.2 2.6 2 0 0 2 2 2 2 G-patch domain Protocadherin PF08374.6 EMR62112.1 - 0.61 9.6 4.1 1.3 8.5 2.8 1.5 1 0 0 1 1 1 0 Protocadherin Pkinase PF00069.20 EMR62113.1 - 2.3e-33 115.4 0.0 1.3e-16 60.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR62113.1 - 6.4e-11 41.8 0.0 9.7e-05 21.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EMR62113.1 - 4.3e-07 29.9 0.0 5.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMR62113.1 - 0.041 12.8 0.0 3.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Menin PF05053.8 EMR62113.1 - 0.26 9.3 3.3 0.36 8.9 2.3 1.1 1 0 0 1 1 1 0 Menin Chorion_2 PF03964.10 EMR62114.1 - 0.018 15.6 0.8 0.018 15.6 0.6 2.0 2 0 0 2 2 2 0 Chorion family 2 BTB PF00651.26 EMR62114.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Ribosomal_L10 PF00466.15 EMR62116.1 - 4.5e-25 87.4 0.2 9.9e-25 86.3 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EMR62116.1 - 1.9e-15 57.0 6.0 8.7e-15 54.8 3.1 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein SopA PF13981.1 EMR62116.1 - 0.072 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 SopA-like central domain VirE_N PF08800.5 EMR62116.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 VirE N-terminal domain Phage_holin PF04688.8 EMR62116.1 - 0.13 11.7 0.2 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Phage lysis protein, holin CAP_GLY PF01302.20 EMR62117.1 - 9.4e-18 63.6 0.3 2.4e-17 62.3 0.2 1.6 1 0 0 1 1 1 1 CAP-Gly domain Med4 PF10018.4 EMR62117.1 - 0.0035 16.7 3.4 0.0035 16.7 2.4 3.5 3 1 1 5 5 4 1 Vitamin-D-receptor interacting Mediator subunit 4 AAA_13 PF13166.1 EMR62117.1 - 0.011 14.1 14.2 0.0035 15.8 6.7 1.9 1 1 1 2 2 2 0 AAA domain NPV_P10 PF05531.7 EMR62117.1 - 0.014 15.6 6.1 0.58 10.4 0.5 2.9 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EMR62117.1 - 0.018 14.2 2.8 0.22 10.6 1.2 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 EMR62117.1 - 0.083 13.0 13.3 0.4 10.8 1.8 3.4 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Flagellin_N PF00669.15 EMR62117.1 - 0.086 12.6 6.5 0.19 11.5 0.2 3.1 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region BAR_2 PF10455.4 EMR62117.1 - 0.12 11.2 18.6 2.9 6.7 7.0 2.3 1 1 1 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF305 PF03713.8 EMR62117.1 - 0.12 12.1 9.3 1.4 8.7 4.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF305) Tup_N PF08581.5 EMR62117.1 - 0.2 11.9 0.1 0.2 11.9 0.1 4.6 4 2 2 6 6 6 0 Tup N-terminal Baculo_PEP_C PF04513.7 EMR62117.1 - 0.26 11.0 2.8 3.7 7.3 0.6 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 EMR62117.1 - 0.38 9.3 24.1 0.18 10.4 1.3 3.2 2 1 1 4 4 4 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 EMR62117.1 - 0.93 9.3 40.7 0.078 12.7 2.9 5.7 3 1 2 5 5 5 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.6 EMR62117.1 - 1.1 8.7 20.0 0.032 13.6 1.5 3.6 3 1 0 4 4 4 0 Phage minor structural protein GP20 DivIC PF04977.10 EMR62117.1 - 1.2 8.6 0.0 1.2 8.6 0.0 5.0 5 1 0 5 5 5 0 Septum formation initiator zf-CCHC_4 PF14392.1 EMR62117.1 - 2 8.1 3.8 8.6 6.1 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle FlxA PF14282.1 EMR62117.1 - 2.6 8.0 12.1 2.4 8.1 1.1 3.6 2 1 2 4 4 4 0 FlxA-like protein EMP24_GP25L PF01105.19 EMR62117.1 - 2.7 7.6 7.9 3 7.5 0.5 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD FUSC PF04632.7 EMR62117.1 - 6.4 5.0 15.4 0.42 8.9 7.0 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.7 EMR62117.1 - 6.9 6.4 22.4 20 4.9 0.4 3.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein MutS_V PF00488.16 EMR62118.1 - 1.9e-59 200.8 0.1 3.5e-59 200.0 0.1 1.4 1 1 0 1 1 1 1 MutS domain V BAH PF01426.13 EMR62119.1 - 0.00017 21.3 0.4 0.00058 19.6 0.0 2.2 2 0 0 2 2 2 1 BAH domain GATA PF00320.22 EMR62119.1 - 0.038 13.3 0.6 0.038 13.3 0.4 2.4 2 0 0 2 2 2 0 GATA zinc finger Mif2_N PF15624.1 EMR62119.1 - 3 8.4 7.2 1.9 9.0 3.2 2.0 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal WD40 PF00400.27 EMR62120.1 - 0.0016 18.2 0.1 0.24 11.3 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat NSP2_assoc PF14758.1 EMR62120.1 - 0.024 14.7 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Non-essential region of nsp2 of arterivirus polyprotein MxiM PF11441.3 EMR62120.1 - 0.15 12.1 0.0 0.56 10.2 0.0 1.8 1 1 0 2 2 2 0 Pilot protein MxiM Nop14 PF04147.7 EMR62121.1 - 3.5e-205 683.5 57.8 1.1e-161 539.7 23.2 2.0 1 1 1 2 2 2 2 Nop14-like family MFS_1 PF07690.11 EMR62122.1 - 8.3e-18 64.2 26.7 8.3e-18 64.2 18.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR62122.1 - 2.4e-06 26.2 12.0 2.4e-06 26.2 8.3 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.19 EMR62122.1 - 0.0022 16.6 24.7 0.0092 14.5 15.1 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3938 PF13074.1 EMR62122.1 - 0.0039 17.0 0.2 0.012 15.4 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3938) DUF2811 PF10929.3 EMR62122.1 - 0.018 15.0 0.1 0.044 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) SpoIISA_toxin PF14171.1 EMR62122.1 - 1.7 7.8 7.2 0.091 12.0 0.8 1.8 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system EF-hand_6 PF13405.1 EMR62123.1 - 2.9e-07 29.8 1.0 0.00087 18.9 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EMR62123.1 - 1.9e-05 24.7 0.8 1.9e-05 24.7 0.6 2.2 2 2 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EMR62123.1 - 2.6e-05 23.1 0.3 0.0003 19.8 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 EMR62123.1 - 3.1e-05 23.0 1.4 7.8e-05 21.8 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EMR62123.1 - 0.0013 18.3 1.0 0.0033 17.0 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair LigA PF07746.6 EMR62123.1 - 0.16 12.0 0.3 0.55 10.2 0.0 2.0 2 1 0 2 2 2 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit PI3K_p85B PF02192.11 EMR62123.1 - 0.25 10.7 1.2 3 7.3 0.3 2.3 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain NUDIX PF00293.23 EMR62124.1 - 1.8e-17 63.2 1.1 2.7e-17 62.6 0.7 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4083 PF13314.1 EMR62126.1 - 0.3 10.9 0.8 0.59 10.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) SNN_transmemb PF09049.5 EMR62126.1 - 1.2 8.8 4.9 2.2 8.0 3.4 1.4 1 0 0 1 1 1 0 Stannin transmembrane Tn7_Tnp_TnsA_C PF08721.6 EMR62127.1 - 0.064 13.2 0.6 0.15 12.1 0.2 1.8 2 0 0 2 2 2 0 TnsA endonuclease C terminal adh_short PF00106.20 EMR62128.1 - 3.3e-28 98.6 4.8 4.4e-28 98.2 3.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR62128.1 - 9.5e-24 84.4 0.1 1.1e-23 84.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR62128.1 - 2.2e-11 43.7 2.1 4.6e-11 42.7 1.5 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR62128.1 - 0.00015 21.3 0.2 0.0003 20.2 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CVNH PF08881.5 EMR62129.1 - 0.00016 21.8 0.0 0.0011 19.1 0.0 1.9 1 1 0 1 1 1 1 CVNH domain ORC6 PF05460.8 EMR62130.1 - 1.5e-37 129.5 0.1 1.5e-37 129.5 0.1 1.4 2 0 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) Glyco_hydro_12 PF01670.11 EMR62131.1 - 3e-33 114.8 0.4 3e-33 114.8 0.2 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 Phage_holin_5 PF06946.6 EMR62131.1 - 1.1 9.4 7.5 0.35 11.0 1.2 2.5 1 1 1 2 2 2 0 Phage holin Mito_carr PF00153.22 EMR62132.1 - 1e-45 153.3 8.2 3.3e-16 58.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Osmo_MPGsynth PF09488.5 EMR62133.1 - 2.7e-132 441.0 0.0 3.9e-132 440.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) PhyH PF05721.8 EMR62135.1 - 1.6e-18 67.4 0.0 3.1e-18 66.5 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) GNAT_acetyltr_2 PF13718.1 EMR62136.1 - 6e-78 260.6 0.0 1e-77 259.8 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EMR62136.1 - 6e-67 224.6 0.1 2.7e-66 222.5 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EMR62136.1 - 4.6e-38 128.7 0.2 1.8e-37 126.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EMR62136.1 - 7.3e-33 112.6 0.5 2e-32 111.3 0.3 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_22 PF13401.1 EMR62136.1 - 0.00059 19.9 0.0 0.065 13.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain Acetyltransf_7 PF13508.1 EMR62136.1 - 0.052 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3336 PF11815.3 EMR62137.1 - 2.3e-40 137.4 1.9 3.5e-40 136.8 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EMR62137.1 - 1.1e-21 77.7 0.0 1.7e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase p450 PF00067.17 EMR62138.1 - 2.8e-69 233.8 0.0 3.3e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AhpC-TSA PF00578.16 EMR62139.1 - 1.8e-31 108.4 0.0 2.5e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EMR62139.1 - 1.3e-12 47.1 0.2 2.8e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EMR62139.1 - 2.9e-11 43.1 0.0 3.8e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin NMT_C PF02799.10 EMR62140.1 - 1.2e-75 253.0 0.1 1.8e-75 252.5 0.1 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EMR62140.1 - 3.6e-74 247.7 0.0 7.2e-74 246.8 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 EMR62140.1 - 0.015 15.1 0.0 0.08 12.8 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Dynamin_N PF00350.18 EMR62142.1 - 4.5e-30 104.6 0.3 1.6e-29 102.8 0.1 2.1 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EMR62142.1 - 4.9e-16 58.3 0.0 2.6e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EMR62142.1 - 1.1e-05 25.3 0.0 6e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 EMR62142.1 - 0.00017 21.4 0.1 0.0006 19.6 0.0 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain AAA_21 PF13304.1 EMR62142.1 - 0.0035 17.3 0.0 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EMR62142.1 - 0.014 15.8 0.0 0.036 14.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 EMR62142.1 - 0.027 13.7 0.0 3.5 6.8 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_29 PF13555.1 EMR62142.1 - 0.036 13.5 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ZZ PF00569.12 EMR62143.1 - 1.3e-10 40.6 7.4 2.6e-10 39.6 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 EMR62143.1 - 9e-10 37.1 3.8 0.0011 18.1 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EMR62143.1 - 1.5e-06 28.2 6.7 1.7e-05 24.8 2.7 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 EMR62143.1 - 1.2e-05 24.7 1.5 0.039 13.5 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EMR62143.1 - 3.8e-05 23.2 4.6 0.071 13.0 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain VID27 PF08553.5 EMR62143.1 - 0.62 8.2 7.0 1.3 7.2 4.8 1.4 1 0 0 1 1 1 0 VID27 cytoplasmic protein C1_3 PF07649.7 EMR62143.1 - 0.92 9.6 9.2 1.6 8.8 6.4 1.4 1 0 0 1 1 1 0 C1-like domain PEP_mutase PF13714.1 EMR62144.1 - 4.1e-39 134.2 0.1 5.3e-39 133.8 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EMR62144.1 - 6.2e-11 41.1 0.0 1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Isocitrate lyase family Peptidase_M50B PF13398.1 EMR62145.1 - 1.3e-54 184.6 21.5 1.6e-54 184.3 14.9 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 EMR62145.1 - 0.012 14.5 0.4 0.012 14.5 0.3 2.8 2 2 2 4 4 4 0 Peptidase family M50 Patched PF02460.13 EMR62145.1 - 1.5 6.6 5.5 2.4 5.9 3.8 1.3 1 0 0 1 1 1 0 Patched family MLANA PF14991.1 EMR62145.1 - 6.3 6.8 8.5 5.7 6.9 1.6 2.4 1 1 1 2 2 2 0 Protein melan-A Abhydrolase_6 PF12697.2 EMR62146.1 - 1.1e-28 100.6 0.0 1.3e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR62146.1 - 7.6e-13 48.5 0.0 8.9e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR62146.1 - 7.1e-11 42.0 0.0 1e-10 41.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMR62146.1 - 0.00021 21.0 0.0 0.00051 19.8 0.0 1.6 1 1 0 1 1 1 1 Putative lysophospholipase tRNA-synt_1c PF00749.16 EMR62147.1 - 7.2e-52 175.9 0.0 4.3e-33 114.3 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EMR62147.1 - 1.1e-28 100.0 0.0 5.7e-28 97.7 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Sugar_tr PF00083.19 EMR62148.1 - 3.2e-59 200.6 8.4 2.3e-54 184.6 3.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter NmrA PF05368.8 EMR62148.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Abhydrolase_6 PF12697.2 EMR62149.1 - 2.1e-12 47.4 0.2 3.6e-12 46.6 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR62149.1 - 1.4e-11 44.3 0.1 2.3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMR62149.1 - 2e-05 24.2 0.1 3e-05 23.7 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EMR62149.1 - 0.00012 21.7 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMR62149.1 - 0.00046 19.4 0.6 0.0046 16.2 0.6 2.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EMR62149.1 - 0.0013 18.1 0.4 0.0018 17.7 0.3 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 EMR62149.1 - 0.0083 15.9 0.2 0.022 14.5 0.1 1.7 1 1 1 2 2 2 1 Putative lysophospholipase Cutinase PF01083.17 EMR62149.1 - 0.015 15.0 0.1 0.02 14.6 0.1 1.1 1 0 0 1 1 1 0 Cutinase Adeno_PX PF05829.7 EMR62149.1 - 0.059 12.8 0.4 0.13 11.7 0.3 1.5 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) Abhydrolase_2 PF02230.11 EMR62149.1 - 0.067 12.6 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase SHMT PF00464.14 EMR62149.1 - 0.082 11.2 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Exo_endo_phos PF03372.18 EMR62150.1 - 0.0001 22.3 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4462 PF14692.1 EMR62150.1 - 0.14 11.3 0.1 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) Fungal_trans PF04082.13 EMR62151.1 - 3.3e-17 62.2 1.3 3.3e-17 62.2 0.9 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR62151.1 - 2.9e-14 52.6 19.7 1e-08 34.9 7.5 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 EMR62151.1 - 2.1 6.5 11.6 3.3 5.8 8.1 1.2 1 0 0 1 1 1 0 Transmembrane protein NmrA PF05368.8 EMR62152.1 - 2.2e-25 89.2 0.0 5e-25 88.1 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR62152.1 - 7.9e-10 39.0 1.7 3.4e-09 36.9 1.2 1.9 1 1 0 1 1 1 1 NADH(P)-binding ADH_N PF08240.7 EMR62153.1 - 8.4e-07 28.7 0.0 4.6e-06 26.3 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2314 PF10077.4 EMR62153.1 - 0.0053 16.8 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2314) DnaJ PF00226.26 EMR62155.1 - 2.3e-10 40.0 0.0 4.5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain HXXSHH PF07586.6 EMR62155.1 - 0.041 12.8 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Nucleoplasmin PF03066.10 EMR62156.1 - 0.0027 17.2 2.0 0.0049 16.4 1.4 1.4 1 0 0 1 1 1 1 Nucleoplasmin AAA PF00004.24 EMR62156.1 - 0.043 14.0 0.2 0.19 11.9 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) NOA36 PF06524.7 EMR62156.1 - 0.19 10.9 5.8 0.26 10.5 4.0 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 EMR62156.1 - 0.44 10.8 10.6 1.3 9.3 7.4 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Iso_dh PF00180.15 EMR62157.1 - 5.3e-87 291.9 0.0 6.6e-87 291.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NAD_binding_1 PF00175.16 EMR62158.1 - 1.3e-29 102.9 0.0 2.1e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EMR62158.1 - 2.9e-25 87.8 0.2 5e-25 87.1 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 EMR62158.1 - 3.5e-24 84.7 0.0 6e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EMR62158.1 - 7.8e-06 25.8 0.0 0.0014 18.5 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EMR62158.1 - 0.0015 18.4 0.0 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Glyco_hydro_43 PF04616.9 EMR62159.1 - 1.8e-52 178.2 5.5 2.2e-52 177.9 3.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EMR62159.1 - 6.3e-05 22.4 2.1 8.3e-05 22.0 0.5 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain DUF377 PF04041.8 EMR62159.1 - 0.008 14.9 0.0 0.074 11.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF377) DUF4448 PF14610.1 EMR62160.1 - 4.1e-35 120.9 0.1 6.5e-35 120.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Kringle PF00051.13 EMR62160.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Kringle domain Abhydrolase_6 PF12697.2 EMR62161.1 - 2.8e-22 79.7 0.3 3.5e-22 79.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR62161.1 - 4.5e-15 55.8 0.0 1.7e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR62161.1 - 2.2e-08 33.9 0.0 4.8e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EMR62161.1 - 0.0073 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein DUF1100 PF06500.6 EMR62161.1 - 0.017 13.7 0.0 0.023 13.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) UPF0227 PF05728.7 EMR62161.1 - 0.024 14.3 0.0 5.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.8 EMR62161.1 - 0.025 14.1 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 EMR62161.1 - 0.037 14.2 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.3 EMR62161.1 - 0.077 12.8 0.0 0.34 10.7 0.0 2.2 2 0 0 2 2 2 0 Putative lysophospholipase Amidoligase_2 PF12224.3 EMR62162.1 - 2.4e-14 53.5 1.5 5.7e-13 49.0 0.1 2.4 3 0 0 3 3 3 2 Putative amidoligase enzyme DcpS_C PF11969.3 EMR62163.1 - 1.2e-21 77.0 0.0 2.7e-21 75.9 0.0 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EMR62163.1 - 1.6e-19 70.2 0.0 1.1e-17 64.4 0.0 2.3 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Fungal_trans PF04082.13 EMR62164.1 - 8.3e-26 90.4 0.0 4.8e-25 87.9 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_47 PF01532.15 EMR62165.1 - 3.3e-93 312.8 0.0 4.4e-93 312.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 EMR62165.1 - 0.038 13.3 0.1 0.081 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) MFS_1 PF07690.11 EMR62166.1 - 1.5e-32 112.7 45.9 1.5e-32 112.7 31.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR62166.1 - 2.6e-10 39.1 7.5 2.6e-10 39.1 5.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2937 PF11157.3 EMR62166.1 - 0.086 12.1 0.7 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Myb_Cef PF11831.3 EMR62167.1 - 7.6e-59 198.7 8.0 7.6e-59 198.7 5.5 4.2 4 1 1 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EMR62167.1 - 6.2e-22 77.3 4.1 2.5e-10 40.2 0.2 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMR62167.1 - 1.8e-20 72.7 9.4 9.7e-14 51.2 2.7 3.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.3 EMR62167.1 - 5.4 6.9 10.2 0.48 10.3 0.1 3.8 3 1 1 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain GILT PF03227.11 EMR62168.1 - 2.2e-12 46.7 1.1 2.4e-12 46.6 0.2 1.5 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Na_Ca_ex PF01699.19 EMR62169.1 - 3.4e-37 127.1 29.2 9.5e-23 80.3 8.5 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CASP_C PF08172.7 EMR62170.1 - 0.0095 14.9 0.9 0.011 14.8 0.6 1.0 1 0 0 1 1 1 1 CASP C terminal Ank PF00023.25 EMR62172.1 - 5.4e-06 25.9 0.0 1.9e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 EMR62172.1 - 9.4e-05 22.5 0.2 0.00036 20.6 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMR62172.1 - 0.00012 22.3 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMR62172.1 - 0.00025 21.4 0.1 0.0084 16.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR62172.1 - 0.035 14.3 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat Glyco_hydro_76 PF03663.9 EMR62175.1 - 6.2e-129 430.5 4.3 8.1e-129 430.2 3.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 TauD PF02668.11 EMR62176.1 - 2.4e-36 125.7 0.1 2.9e-36 125.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAG1 PF05454.6 EMR62176.1 - 0.025 13.7 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Med3 PF11593.3 EMR62177.1 - 0.32 10.1 2.6 0.52 9.5 1.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DNA_pol3_a_NII PF11490.3 EMR62177.1 - 0.57 9.8 5.4 0.092 12.3 0.3 1.9 1 1 1 2 2 2 0 DNA polymerase III polC-type N-terminus II DUF4266 PF14086.1 EMR62177.1 - 2.8 8.5 7.1 13 6.3 4.9 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) DUF2514 PF10721.4 EMR62177.1 - 7.5 6.2 23.1 12 5.5 16.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) p450 PF00067.17 EMR62178.1 - 2.2e-43 148.4 0.0 2.5e-42 144.9 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 SUZ PF12752.2 EMR62178.1 - 2 9.0 4.7 0.69 10.4 0.7 2.1 2 0 0 2 2 2 0 SUZ domain Sulfatase PF00884.18 EMR62179.1 - 3.7e-46 157.7 0.0 4.8e-45 154.0 0.0 2.2 1 1 0 1 1 1 1 Sulfatase Amidase PF01425.16 EMR62180.1 - 6.4e-26 91.1 5.5 5.5e-21 74.9 4.2 3.6 3 1 0 3 3 3 3 Amidase GWT1 PF06423.7 EMR62181.1 - 1.1e-43 148.5 1.9 2.4e-43 147.5 1.3 1.6 1 0 0 1 1 1 1 GWT1 tRNA-synt_1b PF00579.20 EMR62182.1 - 1.9e-58 197.8 0.1 2.7e-58 197.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PAP_central PF04928.12 EMR62183.1 - 6.8e-24 84.0 0.0 1.4e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain DUF504 PF04457.7 EMR62183.1 - 4e-11 42.8 0.2 7.5e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF504) NTP_transf_2 PF01909.18 EMR62183.1 - 0.00011 22.4 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_RNA-bind PF04926.10 EMR62183.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain Nrap PF03813.9 EMR62183.1 - 0.0065 14.0 0.0 0.009 13.6 0.0 1.1 1 0 0 1 1 1 1 Nrap protein LZ_Tnp_IS66 PF13007.2 EMR62183.1 - 0.13 12.9 1.1 0.31 11.7 0.8 1.6 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain ClpS PF02617.12 EMR62184.1 - 1.3e-06 28.0 0.1 2.9e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.15 EMR62184.1 - 0.0002 21.0 0.2 0.00062 19.4 0.1 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 EMR62184.1 - 0.006 16.3 3.4 0.006 16.3 2.4 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMR62184.1 - 0.35 10.9 11.2 1.2 9.2 1.5 3.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CAP_N PF01213.14 EMR62184.1 - 0.66 9.2 2.1 1.5 8.0 1.3 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.20 EMR62185.1 - 0.021 13.9 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain HAD_2 PF13419.1 EMR62187.1 - 1.2e-28 100.4 0.1 1.7e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR62187.1 - 2.5e-05 23.8 0.0 4.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EMR62187.1 - 0.011 16.2 0.0 0.16 12.3 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ApoO PF09769.4 EMR62188.1 - 2e-44 151.1 0.0 3.1e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Apolipoprotein O FKBP_C PF00254.23 EMR62189.1 - 2.3e-31 107.6 0.1 8.7e-31 105.8 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2031 PF09592.5 EMR62189.1 - 0.3 10.1 3.2 0.64 9.1 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Mago-bind PF09282.5 EMR62190.1 - 3.8e-12 45.5 2.2 7.7e-12 44.5 1.5 1.5 1 0 0 1 1 1 1 Mago binding RR_TM4-6 PF06459.7 EMR62190.1 - 0.029 14.2 8.0 0.036 13.9 5.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TATR PF03430.8 EMR62190.1 - 0.52 8.8 3.6 0.71 8.4 2.5 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator FA_desaturase PF00487.19 EMR62191.1 - 6.7e-19 68.3 34.2 7.1e-19 68.2 21.5 2.4 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.3 EMR62191.1 - 0.02 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Pkinase PF00069.20 EMR62192.1 - 6.7e-30 104.0 0.0 2.8e-23 82.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR62192.1 - 1.5e-12 47.1 0.0 5e-11 42.1 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.19 EMR62192.1 - 0.0028 18.1 3.2 0.085 13.3 2.2 2.5 1 1 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 EMR62192.1 - 0.0062 16.2 3.0 0.011 15.4 0.1 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMR62192.1 - 0.1 11.5 0.0 0.25 10.2 0.0 1.5 2 0 0 2 2 2 0 Kinase-like IMS PF00817.15 EMR62193.1 - 5.7e-40 136.5 0.0 1.2e-39 135.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EMR62193.1 - 8.6e-17 61.2 0.0 1.7e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EMR62193.1 - 7.5e-09 35.4 23.0 9.9e-05 22.2 4.6 4.0 2 2 0 2 2 2 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 EMR62193.1 - 0.0017 18.3 0.3 0.012 15.6 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif F420_ligase PF01996.11 EMR62193.1 - 0.011 14.8 0.0 0.024 13.7 0.0 1.5 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase PSRT PF07636.6 EMR62194.1 - 0.04 13.3 1.1 0.1 12.1 0.8 1.6 1 0 0 1 1 1 0 PSRT DUF605 PF04652.11 EMR62194.1 - 5.8 6.2 21.4 8 5.7 14.8 1.2 1 0 0 1 1 1 0 Vta1 like Thioredoxin PF00085.15 EMR62195.1 - 2.5e-28 97.8 0.1 2.9e-28 97.6 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EMR62195.1 - 4.6e-06 26.7 0.3 7.2e-05 22.9 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMR62195.1 - 4.8e-06 26.5 0.1 0.00045 20.2 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EMR62195.1 - 3.3e-05 23.4 0.1 3.8e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EMR62195.1 - 8.8e-05 22.4 0.1 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.19 EMR62195.1 - 0.001 18.9 0.1 0.0027 17.6 0.0 1.7 1 1 1 2 2 2 1 Glutaredoxin AhpC-TSA PF00578.16 EMR62195.1 - 0.0023 17.6 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMR62195.1 - 0.015 14.8 0.1 0.06 12.8 0.1 1.8 1 1 0 1 1 1 0 Redoxin Glycophorin_A PF01102.13 EMR62196.1 - 0.0086 15.8 2.2 0.0086 15.8 1.6 2.3 1 1 1 2 2 2 1 Glycophorin A Pex14_N PF04695.8 EMR62196.1 - 0.029 14.4 8.4 0.67 10.0 0.6 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Adeno_E3_CR2 PF02439.10 EMR62196.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PspC PF04024.7 EMR62196.1 - 0.14 11.6 0.4 0.28 10.6 0.3 1.4 1 0 0 1 1 1 0 PspC domain Plasmodium_Vir PF05795.6 EMR62196.1 - 0.26 10.4 1.9 0.32 10.1 0.9 1.4 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Granulin PF00396.13 EMR62196.1 - 0.46 10.6 4.6 0.73 9.9 3.2 1.3 1 0 0 1 1 1 0 Granulin Mito_carr PF00153.22 EMR62197.1 - 1.5e-68 226.5 0.5 8.2e-23 79.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 EMR62197.1 - 0.01 15.7 0.0 7.6 6.5 0.0 2.6 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Adaptin_N PF01602.15 EMR62198.1 - 9.2e-20 70.4 0.0 1e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Ivy PF08816.6 EMR62198.1 - 0.07 13.1 0.0 6.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Inhibitor of vertebrate lysozyme (Ivy) Nop14 PF04147.7 EMR62198.1 - 1.7 6.4 27.4 2.7 5.8 19.0 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 EMR62198.1 - 6.7 6.0 20.3 3.1 7.0 11.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Fungal_trans_2 PF11951.3 EMR62199.1 - 1e-76 258.0 0.0 1.3e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR62199.1 - 1.6e-06 27.9 9.1 2.7e-06 27.1 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.9 EMR62200.1 - 5.5e-63 212.6 0.1 7.1e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 2OG-FeII_Oxy PF03171.15 EMR62201.1 - 0.004 17.4 0.0 0.014 15.7 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EMR62201.1 - 0.0086 16.5 0.0 0.038 14.4 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF1235 PF06822.7 EMR62201.1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) MFS_1 PF07690.11 EMR62202.1 - 1.9e-23 82.7 60.9 2.2e-22 79.2 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SAM_2 PF07647.12 EMR62203.1 - 6.1e-06 25.9 0.1 1.3e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMR62203.1 - 8.1e-06 25.9 0.1 1.8e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EMR62203.1 - 0.0011 18.7 0.1 0.0029 17.3 0.1 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PH PF00169.24 EMR62203.1 - 0.0027 17.8 0.0 0.03 14.5 0.0 2.6 2 1 0 2 2 2 1 PH domain Ste50p-SAM PF09235.5 EMR62203.1 - 0.059 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Adaptin_N PF01602.15 EMR62204.1 - 4e-31 107.9 0.0 4.9e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 EMR62204.1 - 0.011 15.7 0.0 0.031 14.3 0.0 1.9 1 0 0 1 1 1 0 HEAT repeat CLASP_N PF12348.3 EMR62204.1 - 0.043 13.1 0.2 0.18 11.1 0.0 1.9 1 1 0 2 2 2 0 CLASP N terminal CRISPR_Cse2 PF09485.5 EMR62204.1 - 0.13 12.3 0.6 0.2 11.6 0.4 1.3 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) XdhC_C PF13478.1 EMR62205.1 - 0.13 12.6 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain Exo_endo_phos PF03372.18 EMR62206.1 - 2.4e-23 83.3 0.2 3.3e-23 82.9 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 EMR62207.1 - 2.7e-52 172.8 15.6 6.3e-12 44.8 0.0 8.1 7 1 1 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EMR62207.1 - 2.1e-05 22.8 0.7 0.028 12.5 0.0 3.3 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMR62207.1 - 4.9e-05 22.2 0.0 0.0028 16.4 0.0 3.1 3 1 1 4 4 4 1 Nup133 N terminal like BBS2_Mid PF14783.1 EMR62207.1 - 0.0018 18.0 0.0 0.067 12.9 0.0 2.9 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region IKI3 PF04762.7 EMR62207.1 - 0.0062 14.4 0.0 0.016 13.1 0.0 1.6 2 0 0 2 2 2 1 IKI3 family Cytochrom_D1 PF02239.11 EMR62207.1 - 0.0065 14.8 0.2 3 6.0 0.0 3.1 3 0 0 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.7 EMR62207.1 - 0.095 12.3 1.5 15 5.4 0.0 3.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nuf2 PF03800.9 EMR62208.1 - 5.8e-39 133.4 0.0 5.8e-39 133.4 0.0 2.7 4 0 0 4 4 4 1 Nuf2 family Reo_sigmaC PF04582.7 EMR62208.1 - 0.93 8.6 8.2 3.8 6.5 2.8 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CENP-Q PF13094.1 EMR62208.1 - 1.1 9.2 53.4 0.074 13.0 14.6 3.4 1 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Bacillus_HBL PF05791.6 EMR62208.1 - 6.7 6.0 21.5 0.76 9.1 2.9 3.5 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) WSC PF01822.14 EMR62209.1 - 5e-09 35.9 11.6 4e-06 26.6 4.9 2.4 2 1 0 2 2 2 2 WSC domain MFS_1 PF07690.11 EMR62210.1 - 5.3e-36 124.0 81.5 7.2e-27 94.0 33.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMR62210.1 - 7e-05 22.5 6.4 0.0087 15.8 1.3 3.5 3 0 0 3 3 3 2 MFS_1 like family Sod_Fe_C PF02777.13 EMR62211.1 - 7.2e-12 45.0 0.0 5e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EMR62211.1 - 0.0025 18.0 0.0 0.0039 17.4 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain IU_nuc_hydro PF01156.14 EMR62212.1 - 2.8e-82 276.4 0.0 3.2e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Aminotran_3 PF00202.16 EMR62213.1 - 2.3e-66 223.9 0.0 2.7e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Gag_p24 PF00607.15 EMR62213.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Exo70 PF03081.10 EMR62214.1 - 2.7e-69 233.7 0.1 4e-69 233.1 0.1 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Baculo_PEP_C PF04513.7 EMR62214.1 - 0.00015 21.5 5.8 0.033 14.0 0.2 3.5 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EMR62214.1 - 0.0048 16.5 1.4 9.5 5.7 0.0 3.2 3 0 0 3 3 3 2 IncA protein Apolipoprotein PF01442.13 EMR62214.1 - 0.027 13.9 3.0 0.1 12.1 0.0 2.6 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.5 EMR62214.1 - 1.4 9.0 5.9 10 6.2 0.0 4.0 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family RED_N PF07808.8 EMR62215.1 - 7.2e-08 31.9 11.0 7.2e-08 31.9 7.6 2.2 2 0 0 2 2 2 1 RED-like protein N-terminal region NmrA PF05368.8 EMR62216.1 - 4.8e-12 45.6 0.0 6.2e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR62216.1 - 6.3e-08 32.8 0.0 1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding ABC_tran PF00005.22 EMR62218.1 - 1.1e-51 174.6 0.1 6.1e-29 101.0 0.1 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMR62218.1 - 4.2e-47 160.8 11.0 4.2e-47 160.8 7.6 3.6 3 1 1 4 4 4 1 ABC transporter transmembrane region SMC_N PF02463.14 EMR62218.1 - 1.3e-09 37.6 4.5 0.0015 17.7 0.1 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMR62218.1 - 9.7e-07 28.9 0.4 0.0067 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EMR62218.1 - 2.2e-05 23.7 0.5 0.024 13.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EMR62218.1 - 0.00023 21.0 0.5 1.1 9.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EMR62218.1 - 0.00032 20.1 0.0 0.37 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EMR62218.1 - 0.00069 20.1 0.1 2 8.9 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EMR62218.1 - 0.0012 18.2 0.5 1.7 8.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 EMR62218.1 - 0.0068 16.2 0.2 1.1 9.0 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.1 EMR62218.1 - 0.014 15.3 0.6 20 5.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 EMR62218.1 - 0.014 15.7 3.9 0.62 10.3 0.0 3.0 4 0 0 4 4 4 0 AAA domain AAA_5 PF07728.9 EMR62218.1 - 0.019 14.7 0.0 30 4.3 0.0 3.7 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EMR62218.1 - 0.024 14.3 0.5 0.18 11.4 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 EMR62218.1 - 0.03 14.4 1.4 4.1 7.5 0.0 3.3 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EMR62218.1 - 0.031 13.7 0.1 2.8 7.3 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EMR62218.1 - 0.046 13.1 0.9 2.9 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 EMR62218.1 - 0.069 12.9 4.3 0.41 10.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 EMR62218.1 - 0.098 12.8 0.0 5.9 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AIG1 PF04548.11 EMR62218.1 - 0.14 11.2 0.9 5 6.1 0.0 2.4 2 0 0 2 2 2 0 AIG1 family SbcCD_C PF13558.1 EMR62218.1 - 0.18 11.7 0.6 5.9 6.8 0.2 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MFS_1 PF07690.11 EMR62219.1 - 3.5e-18 65.4 10.6 4.9e-11 41.9 0.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Cullin PF00888.17 EMR62220.1 - 4e-125 418.6 0.0 6.1e-125 418.0 0.0 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EMR62220.1 - 4.4e-20 71.2 5.6 1.1e-18 66.7 1.1 2.5 2 0 0 2 2 2 2 Cullin protein neddylation domain Zeta_toxin PF06414.7 EMR62221.1 - 2.6e-36 124.6 0.0 7.8e-36 123.0 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EMR62221.1 - 0.027 14.4 0.3 0.12 12.3 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain Kri1 PF05178.7 EMR62221.1 - 0.16 12.2 0.1 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 KRI1-like family p450 PF00067.17 EMR62222.1 - 2.7e-14 52.5 0.0 5e-14 51.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Clr5 PF14420.1 EMR62223.1 - 1.4e-17 63.2 6.7 2e-17 62.7 4.6 1.3 1 0 0 1 1 1 1 Clr5 domain AA_permease_2 PF13520.1 EMR62224.1 - 1.3e-38 132.6 47.6 1.6e-38 132.3 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMR62224.1 - 6.6e-20 70.9 37.3 1.2e-19 70.0 25.8 1.3 1 0 0 1 1 1 1 Amino acid permease DUF3842 PF12953.2 EMR62224.1 - 0.68 10.0 2.9 18 5.4 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3842) PfkB PF00294.19 EMR62225.1 - 7.4e-42 143.5 0.2 9.6e-42 143.1 0.2 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ank_2 PF12796.2 EMR62226.1 - 1.3e-101 333.0 12.3 2.7e-22 78.9 0.0 4.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EMR62226.1 - 2.9e-56 184.5 3.8 3.3e-09 36.0 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.1 EMR62226.1 - 1.9e-39 129.7 0.8 4e-05 23.4 0.0 8.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 EMR62226.1 - 3.8e-32 110.0 3.1 2.8e-08 34.0 0.1 5.9 2 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR62226.1 - 7.1e-32 108.7 8.0 1.4e-07 31.5 0.2 6.7 2 1 5 7 7 7 7 Ankyrin repeats (many copies) PEGA PF08308.6 EMR62226.1 - 0.024 14.3 0.1 1.5 8.6 0.0 3.2 3 0 0 3 3 3 0 PEGA domain zf-C2H2_4 PF13894.1 EMR62226.1 - 0.043 14.1 10.8 0.087 13.1 0.5 4.4 4 1 0 4 4 4 0 C2H2-type zinc finger UDPG_MGDP_dh_C PF03720.10 EMR62226.1 - 0.085 13.0 0.0 69 3.6 0.0 4.1 3 1 1 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Abhydrolase_1 PF00561.15 EMR62227.1 - 6.5e-28 97.8 0.0 3.7e-27 95.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR62227.1 - 1.2e-23 84.1 0.1 1.9e-23 83.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR62227.1 - 4.3e-12 45.9 0.0 1.9e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR62227.1 - 8.9e-05 21.8 0.0 0.032 13.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EMR62227.1 - 0.0069 15.8 0.5 0.029 13.7 0.3 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.9 EMR62227.1 - 0.014 13.8 0.0 0.019 13.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.3 EMR62227.1 - 0.017 14.9 0.0 0.056 13.3 0.0 2.0 1 1 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 EMR62227.1 - 0.017 14.5 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIP PF03583.9 EMR62227.1 - 0.042 13.0 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Peptidase_S28 PF05577.7 EMR62227.1 - 0.053 12.0 0.0 0.096 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 HET PF06985.6 EMR62228.1 - 3.6e-21 75.8 0.1 5.4e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PIF PF05092.7 EMR62228.1 - 0.068 11.5 0.0 0.084 11.2 0.0 1.1 1 0 0 1 1 1 0 Per os infectivity RE_Bpu10I PF09549.5 EMR62229.1 - 0.11 12.0 0.1 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Bpu10I restriction endonuclease bZIP_1 PF00170.16 EMR62230.1 - 2.1e-05 24.3 4.7 3.6e-05 23.6 3.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMR62230.1 - 0.002 17.9 6.8 0.0032 17.2 4.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper U79_P34 PF03064.11 EMR62230.1 - 0.42 10.1 4.8 0.56 9.6 3.3 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF605 PF04652.11 EMR62230.1 - 1.3 8.3 17.2 1.7 7.9 11.9 1.2 1 0 0 1 1 1 0 Vta1 like SEEEED PF14797.1 EMR62230.1 - 2.9 8.0 8.0 7.1 6.7 5.6 1.6 1 1 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Methyltransf_23 PF13489.1 EMR62231.1 - 1e-21 77.3 0.0 1.4e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR62231.1 - 2.9e-13 50.3 0.0 7.6e-12 45.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR62231.1 - 5.2e-12 46.1 0.0 8e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR62231.1 - 1.1e-11 44.5 0.0 8.9e-11 41.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR62231.1 - 2.4e-11 43.9 0.0 2.6e-10 40.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR62231.1 - 2.6e-06 27.7 0.0 8.5e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EMR62231.1 - 1.3e-05 24.7 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 EMR62231.1 - 2.7e-05 23.2 0.0 5.9e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EMR62231.1 - 0.00012 21.4 0.0 0.00068 19.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 EMR62231.1 - 0.00046 19.5 0.0 0.00071 18.9 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 EMR62231.1 - 0.0006 19.8 0.0 0.0043 17.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMR62231.1 - 0.00088 19.3 0.0 0.002 18.1 0.0 1.5 1 1 0 2 2 2 1 FtsJ-like methyltransferase CMAS PF02353.15 EMR62231.1 - 0.0051 15.9 0.0 0.0077 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EMR62231.1 - 0.0053 15.9 0.0 0.056 12.5 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF1817 PF08847.6 EMR62231.1 - 0.032 13.7 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1817) DUF938 PF06080.7 EMR62231.1 - 0.056 12.9 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_3 PF01596.12 EMR62231.1 - 0.088 11.8 0.0 0.36 9.8 0.0 1.9 1 1 0 1 1 1 0 O-methyltransferase Na_H_Exchanger PF00999.16 EMR62232.1 - 1.5e-60 204.7 37.5 1.1e-32 113.0 10.1 2.2 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family Glyco_transf_41 PF13844.1 EMR62233.1 - 5.6e-83 278.4 0.0 8.9e-47 159.1 0.0 3.3 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EMR62233.1 - 3.6e-23 80.9 0.4 2.6e-05 23.7 0.0 4.8 4 0 0 4 4 4 4 TPR repeat TPR_1 PF00515.23 EMR62233.1 - 8.5e-19 66.3 0.0 0.00061 19.2 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EMR62233.1 - 2.9e-15 54.8 0.0 0.14 12.1 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMR62233.1 - 1.2e-13 49.7 0.0 0.0021 17.6 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMR62233.1 - 1.4e-13 50.5 0.4 2.5e-06 27.3 0.1 4.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMR62233.1 - 1.2e-11 44.1 0.1 0.031 14.8 0.0 6.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMR62233.1 - 1.1e-10 40.8 0.0 0.063 13.4 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMR62233.1 - 2.7e-09 36.6 0.2 1.3 9.0 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMR62233.1 - 3.3e-06 27.5 0.4 2.7 8.7 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMR62233.1 - 1.3e-05 24.6 0.3 0.84 9.5 0.0 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMR62233.1 - 0.00016 21.9 1.6 2.6 8.4 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat BTAD PF03704.12 EMR62233.1 - 0.003 17.8 0.4 1.5 9.1 0.1 3.0 3 0 0 3 3 3 1 Bacterial transcriptional activator domain Apc3 PF12895.2 EMR62233.1 - 0.0039 17.2 0.5 1.8 8.7 0.0 3.3 3 1 1 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EMR62233.1 - 0.011 15.6 0.4 7.5 6.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMR62233.1 - 0.012 16.0 0.1 34 5.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 EMR62234.1 - 4.2e-26 90.7 1.6 3.6e-12 46.1 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMR62234.1 - 1.1e-17 63.9 3.6 3.5e-10 39.8 0.0 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.1 EMR62234.1 - 0.00074 18.9 0.3 0.37 10.3 0.0 3.2 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain HTH_23 PF13384.1 EMR62234.1 - 0.012 15.2 0.6 0.14 11.8 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain Zip PF02535.17 EMR62234.1 - 0.022 13.7 11.5 0.033 13.2 8.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 EMR62234.1 - 4.2 6.1 20.0 6.7 5.4 13.9 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NicO PF03824.11 EMR62234.1 - 8.9 5.5 6.1 12 5.0 4.2 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Sec23_trunk PF04811.10 EMR62235.1 - 2.4e-79 266.1 0.0 3.3e-79 265.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMR62235.1 - 1.5e-34 117.4 1.4 4.8e-34 115.8 0.1 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMR62235.1 - 4e-30 104.1 0.2 8.1e-30 103.1 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EMR62235.1 - 6.9e-16 57.5 6.8 1.4e-15 56.5 4.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EMR62235.1 - 2.1e-12 46.5 0.0 5.4e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L11_N PF03946.9 EMR62236.1 - 4.1e-18 64.5 0.1 6.3e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EMR62236.1 - 9.7e-10 38.4 0.1 1.6e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Tfb2 PF03849.9 EMR62237.1 - 1.1e-87 294.0 0.0 1.3e-87 293.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 TMV_coat PF00721.16 EMR62238.1 - 1.8 8.4 5.6 0.24 11.3 0.3 2.2 2 1 0 2 2 2 0 Virus coat protein (TMV like) IBN_N PF03810.14 EMR62240.1 - 0.00014 21.6 0.0 0.0011 18.8 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EMR62240.1 - 0.007 16.2 2.4 0.043 13.7 0.0 3.3 4 1 0 4 4 4 1 Exportin 1-like protein Cse1 PF08506.5 EMR62240.1 - 0.017 13.7 0.2 0.033 12.7 0.1 1.4 1 0 0 1 1 1 0 Cse1 Pex2_Pex12 PF04757.9 EMR62241.1 - 7e-39 133.5 0.4 1.2e-38 132.8 0.3 1.4 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EMR62241.1 - 0.032 14.0 4.1 0.07 13.0 2.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ferric_reduct PF01794.14 EMR62241.1 - 0.22 11.5 2.3 0.48 10.5 1.6 1.5 1 0 0 1 1 1 0 Ferric reductase like transmembrane component zf-C3HC4_2 PF13923.1 EMR62241.1 - 0.93 9.5 9.3 0.62 10.1 3.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) tRNA-synt_1b PF00579.20 EMR62242.1 - 7.1e-75 251.8 0.0 9.7e-75 251.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NPR2 PF06218.6 EMR62244.1 - 2.4e-113 379.0 0.0 3.4e-113 378.5 0.0 1.2 1 0 0 1 1 1 1 Nitrogen permease regulator 2 Ribosomal_60s PF00428.14 EMR62244.1 - 0.086 13.2 6.8 0.17 12.2 4.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Macoilin PF09726.4 EMR62244.1 - 0.79 7.9 2.3 1.2 7.2 1.6 1.2 1 0 0 1 1 1 0 Transmembrane protein CybS PF05328.7 EMR62245.1 - 1.7e-51 173.2 0.0 2.3e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 EMR62245.1 - 0.046 13.5 0.3 1.7 8.4 0.0 2.1 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Vps53_N PF04100.7 EMR62246.1 - 3e-99 332.3 0.0 4.6e-99 331.7 0.0 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EMR62246.1 - 7.3e-07 28.3 0.7 1.5e-06 27.3 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Spc7 PF08317.6 EMR62246.1 - 0.0042 15.7 0.3 0.0073 15.0 0.2 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF2451 PF10474.4 EMR62246.1 - 0.028 14.1 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Fungal_trans PF04082.13 EMR62247.1 - 5.7e-16 58.1 1.8 8.2e-16 57.6 0.2 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Na_H_Exchanger PF00999.16 EMR62248.1 - 2e-29 102.2 18.4 2.6e-29 101.9 12.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EMR62248.1 - 0.008 16.0 1.0 0.041 13.8 0.1 2.8 2 1 0 2 2 2 1 YrhC-like protein MFS_1 PF07690.11 EMR62249.1 - 3.4e-39 134.5 28.2 4.1e-39 134.2 19.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily CRAL_TRIO PF00650.15 EMR62251.1 - 5.1e-08 32.5 0.6 5.2e-07 29.2 0.4 2.1 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMR62251.1 - 0.00091 19.3 0.0 0.0077 16.3 0.0 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Colicin_im PF03857.8 EMR62252.1 - 0.093 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Colicin immunity protein Glyco_hydro_18 PF00704.23 EMR62253.1 - 5.7e-47 160.8 0.0 7.2e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MFS_1 PF07690.11 EMR62254.1 - 2.4e-36 125.2 25.6 2.9e-36 124.9 17.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR62254.1 - 6.7e-14 51.3 14.6 7.2e-13 47.9 10.2 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EMR62254.1 - 8.6e-10 37.4 0.5 1.3e-09 36.8 0.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EMR62254.1 - 0.0019 16.3 3.5 0.31 9.0 0.3 2.6 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family SET PF00856.23 EMR62255.1 - 6.7e-12 46.0 0.0 6.3e-11 42.8 0.0 2.2 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EMR62255.1 - 5.3e-09 35.7 10.0 5.3e-09 35.7 6.9 2.4 2 1 0 2 2 2 1 MYND finger Ecl1 PF12855.2 EMR62255.1 - 0.13 11.5 2.7 5.6 6.3 1.5 2.5 2 0 0 2 2 2 0 Life-span regulatory factor Fer4_2 PF12797.2 EMR62255.1 - 0.88 9.6 4.8 0.6 10.1 1.5 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Aldo_ket_red PF00248.16 EMR62256.1 - 2.9e-46 157.5 0.0 3.4e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAA_hydrolase PF01557.13 EMR62257.1 - 2.3e-59 200.4 0.0 2.9e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Aldedh PF00171.17 EMR62258.1 - 1.7e-154 514.5 0.5 1.9e-154 514.4 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF423 PF04241.10 EMR62259.1 - 6.7e-25 86.8 1.9 6.7e-25 86.8 1.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF423) Na_Ca_ex PF01699.19 EMR62259.1 - 0.038 13.6 0.2 0.25 10.9 0.2 1.9 1 1 0 1 1 1 0 Sodium/calcium exchanger protein YwiC PF14256.1 EMR62259.1 - 0.13 12.3 2.4 2.8 8.0 0.2 2.1 1 1 1 2 2 2 0 YwiC-like protein DUF3054 PF11255.3 EMR62260.1 - 5 6.9 7.4 7.1 6.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) AAA PF00004.24 EMR62261.1 - 4.2e-50 169.3 0.0 1.8e-38 131.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR62261.1 - 6.2e-09 36.0 0.4 0.00051 20.1 0.0 3.9 2 2 1 3 3 3 2 AAA domain AAA_14 PF13173.1 EMR62261.1 - 6.2e-08 32.5 0.0 0.0031 17.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMR62261.1 - 1.1e-07 32.0 0.0 0.012 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EMR62261.1 - 1.4e-07 32.3 0.1 0.002 18.9 0.1 2.7 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 EMR62261.1 - 6.4e-07 28.4 0.0 0.011 14.5 0.0 2.1 2 0 0 2 2 2 2 TIP49 C-terminus AAA_2 PF07724.9 EMR62261.1 - 1.5e-06 28.2 0.0 1.9e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) CDC48_N PF02359.13 EMR62261.1 - 2.6e-06 27.2 0.0 1.3e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 EMR62261.1 - 2.7e-06 26.9 0.1 4.9e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_19 PF13245.1 EMR62261.1 - 7.3e-06 25.6 1.2 0.023 14.4 0.0 3.2 3 0 0 3 3 3 2 Part of AAA domain AAA_5 PF07728.9 EMR62261.1 - 1.5e-05 24.7 0.0 0.0012 18.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EMR62261.1 - 2.1e-05 24.4 0.0 0.21 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EMR62261.1 - 2.3e-05 23.6 0.1 0.0032 16.6 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EMR62261.1 - 2.8e-05 23.9 0.1 0.47 10.1 0.0 3.2 2 1 1 3 3 3 1 Archaeal ATPase AAA_18 PF13238.1 EMR62261.1 - 3.2e-05 24.2 0.0 0.0034 17.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EMR62261.1 - 4.1e-05 23.0 0.1 0.06 12.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.7 EMR62261.1 - 8.5e-05 21.7 0.1 0.029 13.4 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EMR62261.1 - 0.00023 21.2 0.0 0.085 13.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase KaiC PF06745.8 EMR62261.1 - 0.00034 19.8 0.2 0.0054 15.8 0.1 2.3 2 0 0 2 2 2 1 KaiC Zeta_toxin PF06414.7 EMR62261.1 - 0.00038 19.5 0.1 0.31 10.1 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.1 EMR62261.1 - 0.0004 20.0 0.5 0.13 11.8 0.2 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EMR62261.1 - 0.00053 19.5 0.0 0.52 9.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EMR62261.1 - 0.00061 19.2 1.7 0.82 9.0 0.0 3.6 2 2 1 4 4 4 1 AAA domain NACHT PF05729.7 EMR62261.1 - 0.0033 17.1 1.9 1.4 8.5 0.0 3.1 4 0 0 4 4 3 1 NACHT domain ABC_tran PF00005.22 EMR62261.1 - 0.0038 17.5 0.5 0.1 12.9 0.0 2.4 2 0 0 2 2 2 1 ABC transporter PhoH PF02562.11 EMR62261.1 - 0.004 16.4 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein NB-ARC PF00931.17 EMR62261.1 - 0.0041 16.0 0.0 1.6 7.5 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain UPF0079 PF02367.12 EMR62261.1 - 0.0089 15.6 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 EMR62261.1 - 0.019 13.9 0.1 0.51 9.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EMR62261.1 - 0.025 14.5 0.0 0.88 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMR62261.1 - 0.052 13.1 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EMR62261.1 - 0.074 12.6 0.0 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EMR62261.1 - 0.17 11.4 0.0 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EMR62261.1 - 0.19 10.5 0.1 0.41 9.4 0.0 1.5 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EMR62261.1 - 0.25 10.2 0.0 15 4.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.4 EMR62261.1 - 0.3 9.6 0.1 5.3 5.5 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Sugar_tr PF00083.19 EMR62262.1 - 2.1e-19 69.4 20.7 3.9e-14 52.0 0.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR62262.1 - 6.8e-13 48.0 26.8 9.9e-11 40.9 2.6 3.1 3 0 0 3 3 3 2 Major Facilitator Superfamily Folate_carrier PF01770.13 EMR62262.1 - 0.015 13.8 4.7 0.026 13.0 3.2 1.3 1 0 0 1 1 1 0 Reduced folate carrier RNase_PH PF01138.16 EMR62264.1 - 0.0001 22.6 0.0 0.00028 21.2 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Spt20 PF12090.3 EMR62264.1 - 0.0016 17.8 0.1 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Spt20 family Suf PF05843.9 EMR62264.1 - 0.0081 15.9 4.0 0.011 15.5 2.8 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) RNase_PH_C PF03725.10 EMR62264.1 - 0.012 15.4 0.2 0.023 14.6 0.2 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Ilar_coat PF01787.11 EMR62264.1 - 0.013 15.0 1.4 0.019 14.5 1.0 1.2 1 0 0 1 1 1 0 Ilarvirus coat protein PEARLI-4 PF05278.7 EMR62264.1 - 0.017 14.4 0.6 0.026 13.8 0.4 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) FimP PF09766.4 EMR62264.1 - 0.038 13.0 6.4 0.055 12.5 4.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein VID27 PF08553.5 EMR62264.1 - 0.11 10.6 1.4 0.14 10.3 1.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein CagX PF03524.10 EMR62264.1 - 0.13 11.5 4.1 0.2 10.9 2.8 1.2 1 0 0 1 1 1 0 Conjugal transfer protein RAB3GAP2_N PF14655.1 EMR62264.1 - 0.2 10.6 2.3 0.3 10.0 1.6 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus APC_CDC26 PF10471.4 EMR62264.1 - 0.22 12.2 14.8 0.5 11.1 10.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 E_Pc_C PF06752.7 EMR62264.1 - 0.3 10.5 8.8 0.48 9.9 6.1 1.4 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus LIM_bind PF01803.11 EMR62264.1 - 0.4 9.7 5.6 0.56 9.2 3.9 1.1 1 0 0 1 1 1 0 LIM-domain binding protein ERF PF04404.7 EMR62264.1 - 2.1 7.8 13.4 3.5 7.1 9.3 1.3 1 0 0 1 1 1 0 ERF superfamily DUF4175 PF13779.1 EMR62264.1 - 2.5 5.6 15.6 3.5 5.2 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 EMR62264.1 - 3.7 5.6 16.0 5 5.2 11.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Methyltransf_23 PF13489.1 EMR62265.1 - 6e-12 45.5 0.0 8.3e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR62265.1 - 2.7e-09 37.3 0.0 4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR62265.1 - 3.4e-07 30.6 0.0 5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR62265.1 - 2e-06 27.4 0.0 3.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR62265.1 - 0.00015 22.3 0.0 0.00021 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EMR62265.1 - 0.006 15.3 0.0 0.0075 15.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Myb_DNA-bind_6 PF13921.1 EMR62266.1 - 9.1e-08 32.0 0.1 1.6e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMR62266.1 - 0.0011 18.9 0.2 0.0023 17.9 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain PBP1_TM PF14812.1 EMR62266.1 - 0.0021 18.3 5.3 0.0021 18.3 3.7 1.9 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Myb_DNA-bind_4 PF13837.1 EMR62266.1 - 0.0024 17.9 0.2 0.0047 17.0 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain AAA_22 PF13401.1 EMR62267.1 - 0.016 15.3 0.0 0.061 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain SapB_1 PF05184.10 EMR62267.1 - 0.089 12.6 2.2 1 9.2 0.0 3.7 4 0 0 4 4 4 0 Saposin-like type B, region 1 Pro-rich_19 PF15455.1 EMR62267.1 - 0.19 10.7 0.0 0.34 9.8 0.0 1.3 1 0 0 1 1 1 0 Proline-rich 19 DUF924 PF06041.6 EMR62268.1 - 2e-11 43.9 0.0 7.2e-11 42.1 0.0 1.8 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) p450 PF00067.17 EMR62269.1 - 2.6e-23 82.3 0.0 2.9e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 EMR62270.1 - 7.5e-33 113.7 0.1 1.4e-32 112.8 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EMR62270.1 - 0.0049 16.6 0.0 0.012 15.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 EMR62270.1 - 0.05 13.4 0.1 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain MFS_1 PF07690.11 EMR62271.1 - 2.3e-13 49.6 55.7 2.7e-09 36.2 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 EMR62272.1 - 6.1e-42 140.0 13.3 1.3e-07 31.1 0.2 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat PUL PF08324.6 EMR62272.1 - 1.4e-40 138.8 0.0 1.9e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 EMR62272.1 - 1.7e-40 137.6 0.4 3e-40 136.8 0.3 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) Nucleoporin_N PF08801.6 EMR62272.1 - 0.0057 15.4 0.0 4.9 5.7 0.0 3.2 2 1 0 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 EMR62272.1 - 0.067 11.3 0.9 1.6 6.7 0.0 3.0 4 1 0 4 4 4 0 Nucleoporin Nup120/160 WD40 PF00400.27 EMR62273.1 - 3.8e-36 121.6 5.8 1.2e-11 44.0 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat SRR1 PF07985.7 EMR62276.1 - 4e-08 33.0 0.0 6.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 SRR1 Oxidored_FMN PF00724.15 EMR62277.1 - 7.3e-39 133.6 0.0 1e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aa_trans PF01490.13 EMR62278.1 - 1.5e-26 92.8 36.0 2.1e-26 92.3 25.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RNase_T PF00929.19 EMR62280.1 - 2e-23 83.4 0.0 2.5e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Rhomboid PF01694.17 EMR62281.1 - 6.2e-07 29.5 0.5 1.3e-06 28.5 0.4 1.5 1 0 0 1 1 1 1 Rhomboid family DUF3918 PF13056.1 EMR62281.1 - 0.14 11.5 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) 2-Hacid_dh_C PF02826.14 EMR62283.1 - 7.2e-36 122.9 0.0 2.5e-22 78.8 0.0 2.8 2 1 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EMR62283.1 - 0.0056 16.7 0.0 0.018 15.0 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh PF00389.25 EMR62283.1 - 0.02 14.3 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Gp_dh_N PF00044.19 EMR62283.1 - 0.024 14.6 0.1 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EMR62283.1 - 0.033 14.6 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 EMR62283.1 - 0.17 12.3 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2450 PF10475.4 EMR62284.1 - 0.0064 15.4 0.4 0.012 14.5 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF1664 PF07889.7 EMR62284.1 - 0.012 15.3 0.7 0.03 14.1 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 EMR62284.1 - 0.041 11.7 3.7 0.049 11.4 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lectin_C PF00059.16 EMR62284.1 - 0.058 14.0 3.5 0.11 13.1 1.7 1.9 2 0 0 2 2 2 0 Lectin C-type domain Spc24 PF08286.6 EMR62284.1 - 0.11 12.1 0.2 0.11 12.1 0.2 2.4 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.3 EMR62284.1 - 0.14 12.0 11.6 0.2 11.5 3.9 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 EMR62284.1 - 0.27 11.0 11.2 0.11 12.2 4.8 2.0 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) TSC22 PF01166.13 EMR62284.1 - 7 6.6 9.7 1.5 8.8 1.0 3.1 3 1 1 4 4 4 0 TSC-22/dip/bun family HSP70 PF00012.15 EMR62285.1 - 4.1e-06 24.9 0.0 1.6e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Hsp70 protein SLR1-BP PF07333.7 EMR62286.1 - 0.0024 18.0 1.8 0.0027 17.8 1.3 1.1 1 0 0 1 1 1 1 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) DUF2667 PF10868.3 EMR62286.1 - 0.011 16.0 1.5 0.013 15.9 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2667) Defensin_2 PF01097.13 EMR62286.1 - 0.37 10.5 4.3 0.52 10.0 3.0 1.2 1 0 0 1 1 1 0 Arthropod defensin Cupin_5 PF06172.6 EMR62287.1 - 4e-29 101.2 0.0 5.8e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) TIM-br_sig_trns PF09370.5 EMR62288.1 - 4.9e-130 432.3 0.0 5.6e-130 432.1 0.0 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 EMR62288.1 - 0.00027 20.1 0.0 0.00041 19.6 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase PcrB PF01884.12 EMR62288.1 - 0.0026 17.0 0.6 1.9 7.6 0.1 3.1 2 1 1 3 3 3 2 PcrB family Radical_SAM PF04055.16 EMR62288.1 - 0.005 17.0 0.0 0.029 14.5 0.0 2.1 2 1 0 2 2 2 1 Radical SAM superfamily PEP_mutase PF13714.1 EMR62288.1 - 0.067 12.3 0.1 0.18 10.9 0.1 1.8 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Zn_clus PF00172.13 EMR62289.1 - 3.8 7.5 9.6 2.9 7.8 0.4 1.9 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MAPEG PF01124.13 EMR62290.1 - 1.3e-20 73.3 0.1 1.4e-20 73.1 0.1 1.0 1 0 0 1 1 1 1 MAPEG family Aminotran_3 PF00202.16 EMR62291.1 - 6.7e-108 360.5 0.0 8.2e-108 360.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EMR62291.1 - 4.2e-05 22.8 0.0 6.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EMR62291.1 - 0.0027 16.7 0.0 0.0047 15.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II COesterase PF00135.23 EMR62292.1 - 1.3e-53 182.5 0.0 2.1e-53 181.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR62292.1 - 1.9e-07 30.9 0.2 4.1e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Y_phosphatase3C PF13348.1 EMR62292.1 - 0.018 15.1 0.1 0.38 10.8 0.1 2.8 2 0 0 2 2 2 0 Tyrosine phosphatase family C-terminal region DUF1771 PF08590.5 EMR62293.1 - 1e-14 54.2 9.5 1.6e-14 53.6 6.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EMR62293.1 - 4e-10 39.7 0.0 1.2e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Smr domain Polysacc_lyase PF14099.1 EMR62294.1 - 0.023 14.3 3.9 0.03 13.9 2.7 1.2 1 0 0 1 1 1 0 Polysaccharide lyase UPF0261 PF06792.6 EMR62296.1 - 3e-128 427.7 4.3 3.3e-106 355.1 0.7 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0261) CoA_trans PF01144.18 EMR62296.1 - 0.013 14.6 0.0 0.027 13.6 0.0 1.6 1 0 0 1 1 1 0 Coenzyme A transferase Abhydrolase_5 PF12695.2 EMR62297.1 - 7.4e-08 32.2 0.0 2e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR62297.1 - 1.6e-07 31.4 0.0 8e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR62297.1 - 0.00098 18.7 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMR62297.1 - 0.11 11.7 0.0 0.78 8.9 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family DEAD PF00270.24 EMR62298.1 - 1.1e-28 99.8 0.0 1.8e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR62298.1 - 2e-17 62.7 0.0 4.2e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR62298.1 - 0.0032 17.3 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMR62298.1 - 0.19 10.5 0.0 0.37 9.5 0.0 1.5 1 1 0 1 1 1 0 SNF2 family N-terminal domain SNARE_assoc PF09335.6 EMR62300.1 - 3.2e-14 53.2 8.3 3.2e-14 53.2 5.8 2.4 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF1049 PF06305.6 EMR62300.1 - 2.8 7.4 5.1 1 8.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DEAD PF00270.24 EMR62301.1 - 7.1e-44 149.2 1.4 1.3e-43 148.4 1.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR62301.1 - 8e-28 96.1 0.1 6.1e-27 93.3 0.1 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR62301.1 - 0.0016 18.3 0.0 0.0033 17.2 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EMR62301.1 - 0.0054 16.3 0.1 0.016 14.8 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMR62301.1 - 0.02 15.0 0.1 0.075 13.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMR62301.1 - 0.027 14.2 0.1 0.086 12.6 0.1 1.9 1 1 0 1 1 1 0 Part of AAA domain CMS1 PF14617.1 EMR62301.1 - 0.055 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 EMR62301.1 - 0.077 12.7 0.1 0.34 10.6 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.20 EMR62301.1 - 0.085 11.9 0.0 0.42 9.6 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Fanconi_A PF03511.9 EMR62301.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein Pkinase PF00069.20 EMR62302.1 - 3.9e-30 104.8 0.0 5e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR62302.1 - 2.3e-23 82.5 0.0 2.7e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMR62302.1 - 0.00011 21.9 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMR62302.1 - 0.059 12.4 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Na_H_Exchanger PF00999.16 EMR62303.1 - 6.7e-70 235.5 30.2 7.9e-70 235.2 20.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TIP41 PF04176.8 EMR62304.1 - 4e-63 211.9 0.1 9.4e-62 207.4 0.0 2.1 1 1 0 1 1 1 1 TIP41-like family HBS1_N PF08938.5 EMR62305.1 - 0.0013 18.7 0.3 0.0068 16.4 0.0 2.0 2 0 0 2 2 2 1 HBS1 N-terminus zf-CCCH PF00642.19 EMR62305.1 - 0.0016 18.0 0.3 0.0026 17.3 0.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CUE PF02845.11 EMR62305.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 CUE domain FMN_dh PF01070.13 EMR62306.1 - 1.9e-109 365.7 0.0 2.7e-109 365.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EMR62306.1 - 1.6e-19 69.5 0.1 4.6e-19 68.0 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.10 EMR62306.1 - 7.3e-05 22.0 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 EMR62306.1 - 0.0001 21.4 0.0 0.077 12.0 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EMR62306.1 - 0.00065 18.7 0.1 0.00092 18.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EMR62306.1 - 0.00073 18.5 1.3 0.0048 15.8 0.1 2.6 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EMR62306.1 - 0.013 14.7 0.3 0.87 8.8 0.0 2.4 1 1 0 2 2 2 0 Histidine biosynthesis protein RhoGAP PF00620.22 EMR62307.1 - 3.4e-35 120.9 0.0 5.6e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Med7 PF05983.6 EMR62307.1 - 0.019 14.7 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 MED7 protein CsbD PF05532.7 EMR62309.1 - 2.8e-06 26.8 8.0 0.0062 16.1 0.3 2.3 1 1 1 2 2 2 2 CsbD-like DUF4438 PF14505.1 EMR62309.1 - 0.14 10.8 2.5 0.15 10.8 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4438) DnaJ PF00226.26 EMR62311.1 - 6.6e-25 86.6 0.5 1.2e-24 85.7 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EMR62311.1 - 3.2e-21 74.9 0.3 4.2e-17 61.8 0.0 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EMR62311.1 - 8.8e-14 51.3 17.9 1.6e-13 50.4 12.4 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EMR62311.1 - 0.0011 18.6 9.1 0.036 13.7 1.3 2.3 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 EMR62311.1 - 2.9 8.2 6.7 2.5 8.4 2.0 2.7 1 1 2 3 3 3 0 Restriction alleviation protein Lar Ank PF00023.25 EMR62312.1 - 2.2e-23 80.8 0.0 3.9e-05 23.2 0.0 8.3 8 2 0 8 8 8 4 Ankyrin repeat Ank_2 PF12796.2 EMR62312.1 - 3.9e-23 81.5 0.0 1.3e-07 31.8 0.0 4.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMR62312.1 - 1.4e-15 56.9 0.7 8.5e-06 25.8 0.0 5.5 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR62312.1 - 4.2e-14 51.2 0.0 0.011 15.9 0.0 6.6 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.1 EMR62312.1 - 1.6e-12 47.5 0.1 0.05 14.1 0.0 5.9 4 3 1 5 5 5 3 Ankyrin repeats (many copies) F-box PF00646.28 EMR62312.1 - 2.3e-05 23.8 0.4 7.9e-05 22.2 0.3 1.9 1 0 0 1 1 1 1 F-box domain BCNT PF07572.7 EMR62313.1 - 2.1e-26 91.6 2.9 4.9e-26 90.4 2.0 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development Mucin PF01456.12 EMR62313.1 - 2.2 8.0 8.3 0.9 9.3 4.0 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3543 PF12063.3 EMR62314.1 - 6.4e-91 303.8 0.7 1e-90 303.1 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EMR62314.1 - 6.5e-63 212.2 0.0 1.3e-62 211.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR62314.1 - 4.1e-42 144.0 0.0 8.4e-42 143.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR62314.1 - 0.037 12.9 0.0 0.21 10.5 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.6 EMR62314.1 - 0.067 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase p450 PF00067.17 EMR62315.1 - 7.2e-57 192.9 0.0 2.6e-56 191.0 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 AAA PF00004.24 EMR62316.1 - 8e-18 64.9 0.0 1.6e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR62316.1 - 1.2e-05 25.4 0.1 0.00059 19.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EMR62316.1 - 0.00052 20.0 0.0 0.0021 18.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EMR62316.1 - 0.0013 18.5 0.0 0.003 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EMR62316.1 - 0.011 16.0 0.0 0.037 14.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMR62316.1 - 0.012 15.0 0.0 0.035 13.5 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 EMR62316.1 - 0.016 16.0 0.6 0.066 14.0 0.0 2.5 2 1 0 2 2 1 0 AAA domain AAA_33 PF13671.1 EMR62316.1 - 0.025 14.4 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMR62316.1 - 0.038 13.7 0.1 0.13 12.0 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 EMR62316.1 - 0.042 12.9 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EMR62316.1 - 0.045 13.3 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S18 PF01084.15 EMR62316.1 - 0.13 12.1 0.3 0.32 10.8 0.2 1.7 1 0 0 1 1 1 0 Ribosomal protein S18 ArgK PF03308.11 EMR62316.1 - 0.14 10.9 0.1 0.59 8.8 0.0 1.9 2 0 0 2 2 2 0 ArgK protein KaiC PF06745.8 EMR62316.1 - 0.24 10.5 1.7 1.3 8.1 0.2 2.6 3 0 0 3 3 3 0 KaiC DUF4611 PF15387.1 EMR62316.1 - 0.34 11.0 6.6 2.6 8.2 0.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) MAPEG PF01124.13 EMR62317.1 - 1.4e-15 57.0 3.3 1.6e-15 56.8 2.3 1.1 1 0 0 1 1 1 1 MAPEG family BTP PF05232.7 EMR62317.1 - 0.86 9.3 5.9 0.5 10.1 0.6 2.2 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family RicinB_lectin_2 PF14200.1 EMR62319.1 - 3.5e-16 59.4 1.0 4e-14 52.8 0.3 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EMR62319.1 - 0.022 14.7 0.5 0.033 14.2 0.3 1.3 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain FGF PF00167.13 EMR62319.1 - 0.098 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Fibroblast growth factor Acyl_transf_1 PF00698.16 EMR62320.1 - 2.9e-22 79.4 0.0 4.4e-12 45.9 0.0 2.0 1 1 1 2 2 2 2 Acyl transferase domain DUF915 PF06028.6 EMR62320.1 - 0.017 14.2 0.0 0.09 11.8 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) F-box-like PF12937.2 EMR62321.1 - 0.0013 18.3 0.0 0.0039 16.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like FAD_binding_2 PF00890.19 EMR62322.1 - 4.8e-41 140.9 1.2 8.4e-41 140.1 0.8 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR62322.1 - 1.8e-08 33.7 2.2 1.8e-08 33.7 1.6 2.8 2 2 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EMR62322.1 - 1e-07 31.4 0.3 3.1e-07 29.8 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR62322.1 - 2e-05 23.2 4.9 0.0005 18.6 0.1 3.4 3 1 1 4 4 4 2 HI0933-like protein GMC_oxred_N PF00732.14 EMR62322.1 - 0.00018 20.7 0.0 0.037 13.1 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.9 EMR62322.1 - 0.00032 20.6 0.0 0.042 13.7 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR62322.1 - 0.00043 19.2 4.5 0.0023 16.8 0.2 2.9 3 1 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EMR62322.1 - 0.0061 16.6 0.1 0.05 13.6 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR62322.1 - 0.025 14.6 0.4 0.087 12.8 0.3 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EMR62322.1 - 0.085 11.8 0.1 0.17 10.8 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EMR62322.1 - 0.092 11.6 0.1 0.2 10.5 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein LCM PF04072.9 EMR62324.1 - 8.6e-40 136.2 0.1 1.1e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase HET PF06985.6 EMR62325.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Lactamase_B_2 PF12706.2 EMR62326.1 - 4.7e-10 39.3 0.0 7.7e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMR62326.1 - 0.00051 19.7 0.0 0.00085 19.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Methyltransf_2 PF00891.13 EMR62327.1 - 2e-26 92.6 0.0 3e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PI-PLC-X PF00388.14 EMR62328.1 - 1.1e-62 209.7 0.0 1.7e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EMR62328.1 - 2.5e-37 127.4 0.0 5.4e-37 126.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EMR62328.1 - 0.00012 21.8 0.0 0.00099 18.9 0.0 2.4 2 0 0 2 2 2 1 C2 domain EF-hand_like PF09279.6 EMR62328.1 - 0.0032 17.4 0.1 0.2 11.7 0.0 2.5 1 1 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like Amidohydro_1 PF01979.15 EMR62329.1 - 1.3e-19 71.0 0.0 9.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EMR62329.1 - 5.4e-15 54.9 0.0 1.4e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EMR62329.1 - 4.4e-10 40.0 0.2 5.5e-07 29.8 0.2 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMR62329.1 - 2.5e-07 30.2 0.8 0.002 17.4 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Rad21_Rec8_N PF04825.8 EMR62330.1 - 4.5e-28 97.4 0.0 6.8e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EMR62330.1 - 4.1e-05 22.6 0.0 9.9e-05 21.4 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein RNase_PH PF01138.16 EMR62331.1 - 3.5e-19 69.4 0.0 1.2e-18 67.6 0.0 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Flavin_Reduct PF01613.13 EMR62331.1 - 0.005 16.7 0.4 0.0094 15.8 0.3 1.5 1 0 0 1 1 1 1 Flavin reductase like domain PBP1_TM PF14812.1 EMR62331.1 - 0.047 13.9 1.0 0.16 12.2 0.7 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Chorion_S16 PF05836.7 EMR62332.1 - 0.033 14.0 0.6 0.037 13.9 0.4 1.2 1 0 0 1 1 1 0 Chorion protein S16 IncA PF04156.9 EMR62333.1 - 6 6.4 8.9 11 5.5 6.2 1.5 1 1 0 1 1 1 0 IncA protein Lzipper-MIP1 PF14389.1 EMR62333.1 - 6.2 7.0 10.3 0.4 10.8 2.7 2.1 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Tyrosinase PF00264.15 EMR62334.1 - 2e-32 113.1 3.0 2e-32 113.1 2.1 1.6 2 0 0 2 2 2 1 Common central domain of tyrosinase Ferric_reduct PF01794.14 EMR62335.1 - 3.2e-19 69.2 3.6 3.2e-19 69.2 2.5 2.6 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EMR62335.1 - 1.5e-14 53.7 0.0 5.4e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EMR62335.1 - 3.3e-09 36.8 0.0 4.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EMR62335.1 - 0.031 14.8 0.0 0.072 13.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain NAD_binding_8 PF13450.1 EMR62336.1 - 1.2e-10 41.2 0.2 3.6e-10 39.7 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMR62336.1 - 2.5e-09 36.7 0.0 3.6e-09 36.2 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EMR62336.1 - 9.5e-06 24.7 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EMR62336.1 - 2.1e-05 23.8 0.2 3.3e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR62336.1 - 5.1e-05 22.3 0.6 7.2e-05 21.7 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMR62336.1 - 0.00011 20.8 0.2 0.00015 20.3 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EMR62336.1 - 0.00035 20.9 0.3 0.0032 17.8 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR62336.1 - 0.00084 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 EMR62336.1 - 0.0039 16.5 0.1 0.0057 16.0 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Thi4 PF01946.12 EMR62336.1 - 0.0058 15.7 0.3 0.0091 15.1 0.2 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EMR62336.1 - 0.0059 16.6 0.0 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMR62336.1 - 0.021 13.9 0.2 0.029 13.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 EMR62336.1 - 0.024 14.0 0.3 0.092 12.1 0.1 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EMR62336.1 - 0.033 14.4 0.3 0.17 12.1 0.2 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EMR62336.1 - 0.044 13.5 0.1 0.11 12.2 0.1 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GDI PF00996.13 EMR62337.1 - 3.6e-31 107.9 0.0 4.7e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor TPR_10 PF13374.1 EMR62338.1 - 0.16 11.9 5.5 2 8.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat MitMem_reg PF13012.1 EMR62339.1 - 1.4e-13 50.8 0.0 2.4e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EMR62339.1 - 2.6e-12 46.5 0.0 4.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3446 PF11928.3 EMR62339.1 - 0.077 13.1 1.8 0.17 12.0 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) GRP PF07172.6 EMR62339.1 - 0.089 13.2 14.0 0.17 12.3 9.7 1.4 1 0 0 1 1 1 0 Glycine rich protein family Ribosomal_L17 PF01196.14 EMR62340.1 - 3.2e-30 104.5 0.1 6.4e-30 103.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L17 DUF3926 PF13080.1 EMR62342.1 - 0.038 13.5 0.8 3.5 7.2 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) DUF1253 PF06862.7 EMR62343.1 - 8.2e-146 485.8 0.0 1e-145 485.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 EMR62343.1 - 0.095 12.1 0.0 9 5.7 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase cwf18 PF08315.7 EMR62344.1 - 1.2e-41 142.2 3.4 1.2e-41 142.2 2.4 2.3 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor Pam16 PF03656.8 EMR62344.1 - 0.012 15.3 0.7 0.012 15.3 0.5 1.9 2 0 0 2 2 2 0 Pam16 Myc_N PF01056.13 EMR62344.1 - 5 6.1 7.6 1 8.4 0.5 2.2 2 0 0 2 2 2 0 Myc amino-terminal region Cofilin_ADF PF00241.15 EMR62347.1 - 1.6e-14 53.9 0.0 1.7e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PD40 PF07676.7 EMR62348.1 - 9.8e-50 165.5 18.3 3.2e-07 29.8 0.0 9.9 9 1 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 EMR62348.1 - 2e-12 46.3 5.9 0.018 13.6 0.1 7.3 4 2 1 6 6 6 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region TruB_C PF09142.6 EMR62348.1 - 0.024 14.2 0.0 9.6 5.9 0.0 4.1 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal Gmad1 PF10647.4 EMR62348.1 - 0.036 13.4 4.0 0.15 11.4 0.3 3.4 3 2 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain DUF1513 PF07433.6 EMR62348.1 - 0.057 12.3 0.0 13 4.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) WD40 PF00400.27 EMR62348.1 - 9.4 6.2 9.6 1e+02 3.0 0.1 6.1 8 0 0 8 8 8 0 WD domain, G-beta repeat F-box-like PF12937.2 EMR62349.1 - 0.014 15.1 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like IKI3 PF04762.7 EMR62350.1 - 2.6e-94 316.8 0.5 4.1e-84 283.0 0.5 2.1 1 1 1 2 2 2 2 IKI3 family Tom5 PF10642.4 EMR62350.1 - 0.26 10.9 1.2 0.62 9.7 0.3 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase NuiA PF07924.6 EMR62351.1 - 0.088 12.7 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein RabGAP-TBC PF00566.13 EMR62353.1 - 3.2e-15 56.2 0.3 5.7e-15 55.3 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 EMR62353.1 - 1.9e-06 27.8 0.7 5.3e-05 23.2 0.2 3.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EMR62353.1 - 4.1e-05 22.5 3.2 0.03 13.6 0.1 4.1 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.1 EMR62353.1 - 7.1e-05 22.3 2.8 0.0056 16.4 0.2 3.9 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.1 EMR62353.1 - 0.0046 16.2 2.4 0.035 13.4 0.6 3.3 3 0 0 3 3 3 1 EF hand Sigma70_ner PF04546.8 EMR62353.1 - 1.5 8.3 8.9 6.1 6.4 1.4 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region WSC PF01822.14 EMR62354.1 - 8.1e-23 80.1 32.0 2.3e-08 33.8 6.0 3.7 3 0 0 3 3 3 3 WSC domain Baculo_44 PF04631.7 EMR62354.1 - 0.065 11.8 0.8 0.47 9.0 0.0 2.1 2 0 0 2 2 2 0 Baculovirus hypothetical protein zf-RING_2 PF13639.1 EMR62355.1 - 0.0063 16.3 4.0 0.0063 16.3 2.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EMR62355.1 - 0.021 14.5 2.8 0.052 13.2 2.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger FYDLN_acid PF09538.5 EMR62355.1 - 1.1 9.8 4.4 25 5.4 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C3HC4_2 PF13923.1 EMR62355.1 - 2 8.5 9.7 0.15 12.1 2.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) EIIBC-GUT_N PF03612.9 EMR62355.1 - 3 7.4 4.9 4.5 6.8 3.4 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus PAT1 PF09770.4 EMR62355.1 - 3.9 5.5 29.2 4.7 5.3 20.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-RING_5 PF14634.1 EMR62355.1 - 5.7 6.7 10.6 0.091 12.4 2.0 2.1 2 0 0 2 2 2 0 zinc-RING finger domain TFIIA PF03153.8 EMR62355.1 - 6.9 6.4 18.6 9.4 6.0 12.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec62 PF03839.11 EMR62355.1 - 7.1 5.9 8.7 9.8 5.5 6.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 zf-C3HC4_3 PF13920.1 EMR62355.1 - 7.4 6.3 8.6 1.5 8.5 2.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MFS_1 PF07690.11 EMR62356.1 - 2.4e-22 79.1 36.0 2.4e-22 79.1 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2975 PF11188.3 EMR62356.1 - 3.3 7.4 13.9 1.4 8.6 1.0 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF2975) ALO PF04030.9 EMR62357.1 - 4.6e-91 304.9 2.6 6.5e-91 304.5 1.8 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EMR62357.1 - 1e-27 96.3 0.0 1.6e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BTB PF00651.26 EMR62358.1 - 4e-22 78.3 0.4 1.3e-11 44.4 0.3 2.9 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.2 EMR62358.1 - 6.1e-10 39.3 0.0 1.7e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMR62358.1 - 1.4e-09 37.2 0.8 2.6e-05 23.7 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EMR62358.1 - 1e-08 35.4 0.1 2.5e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR62358.1 - 6.7e-07 28.9 0.2 0.0031 17.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EMR62358.1 - 3.9e-06 26.9 0.1 1.1e-05 25.4 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Pkinase PF00069.20 EMR62359.1 - 1.7e-63 214.2 0.0 1.9e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR62359.1 - 2.2e-32 112.1 0.0 2.8e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR62359.1 - 8.1e-06 25.0 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMR62359.1 - 0.00097 18.9 0.2 0.0081 15.9 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EMR62359.1 - 0.031 13.1 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 EMR62360.1 - 1.9e-48 164.8 0.1 5.7e-48 163.3 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR62360.1 - 9.9e-32 110.0 0.0 6.9e-31 107.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase NCA2 PF08637.5 EMR62360.1 - 0.012 14.5 0.0 0.04 12.7 0.0 1.8 2 0 0 2 2 2 0 ATP synthase regulation protein NCA2 DUF99 PF01949.11 EMR62360.1 - 0.038 13.1 0.3 0.071 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF99 OmpH PF03938.9 EMR62360.1 - 0.64 9.9 12.5 0.52 10.2 6.8 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HI0933_like PF03486.9 EMR62360.1 - 0.84 8.0 2.8 1.4 7.3 1.9 1.2 1 0 0 1 1 1 0 HI0933-like protein Matrilin_ccoil PF10393.4 EMR62360.1 - 9.7 5.6 11.0 6.1 6.3 0.9 2.7 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Glyco_hydro_65C PF03633.10 EMR62361.1 - 0.39 10.8 4.7 5.5 7.1 0.0 3.7 4 0 0 4 4 4 0 Glycosyl hydrolase family 65, C-terminal domain DUF2205 PF10224.4 EMR62363.1 - 0.0039 16.7 2.3 0.0039 16.7 1.6 1.9 1 1 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) ERM PF00769.14 EMR62363.1 - 0.0078 15.7 6.7 0.01 15.4 4.6 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family HALZ PF02183.13 EMR62363.1 - 0.011 15.3 1.0 0.011 15.3 0.7 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper MAD PF05557.8 EMR62363.1 - 0.07 11.2 6.5 0.087 10.9 4.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Uds1 PF15456.1 EMR62363.1 - 0.11 12.4 0.7 0.11 12.4 0.5 2.3 1 1 1 2 2 2 0 Up-regulated During Septation APG6 PF04111.7 EMR62363.1 - 0.16 11.0 2.5 0.21 10.6 1.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF904 PF06005.7 EMR62363.1 - 0.2 11.9 4.1 0.52 10.6 2.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) IncA PF04156.9 EMR62363.1 - 0.59 9.6 7.7 0.92 9.0 5.4 1.3 1 0 0 1 1 1 0 IncA protein TPR_MLP1_2 PF07926.7 EMR62363.1 - 1 9.0 6.3 1.8 8.3 4.4 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Choline_kinase PF01633.15 EMR62364.1 - 0.028 13.9 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase MARVEL PF01284.18 EMR62365.1 - 0.044 13.5 7.5 0.051 13.3 4.1 1.6 1 1 1 2 2 2 0 Membrane-associating domain DUF846 PF05832.7 EMR62365.1 - 1.3 8.6 8.5 0.3 10.7 1.4 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) COX7C PF02935.11 EMR62366.1 - 2.5e-13 49.6 1.7 3.3e-13 49.2 1.1 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc CPSF73-100_C PF11718.3 EMR62367.1 - 2.2e-72 242.9 1.9 7.3e-70 234.6 1.9 2.9 2 1 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EMR62367.1 - 3.9e-33 114.0 0.0 8.1e-33 113.0 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EMR62367.1 - 1.4e-14 54.2 0.8 3.8e-14 52.7 0.6 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMR62367.1 - 9.3e-12 44.8 5.1 1.1e-11 44.6 0.4 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EMR62367.1 - 3.8e-08 33.0 0.2 7.6e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EMR62367.1 - 1.4e-05 24.8 0.1 1.4e-05 24.8 0.1 1.9 2 0 0 2 2 1 1 Beta-lactamase superfamily domain Myc_N PF01056.13 EMR62367.1 - 0.03 13.4 6.6 0.057 12.5 4.6 1.4 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.9 EMR62367.1 - 2.4 6.0 10.3 4.4 5.2 7.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.6 EMR62367.1 - 6.1 5.4 7.0 9.5 4.7 4.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RRN3 PF05327.6 EMR62367.1 - 9.8 4.1 8.4 15 3.5 5.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Spore_coat_CotO PF14153.1 EMR62367.1 - 10 5.5 10.5 21 4.5 7.3 1.5 1 0 0 1 1 1 0 Spore coat protein CotO CN_hydrolase PF00795.17 EMR62368.1 - 2e-22 79.4 0.2 2.5e-20 72.5 0.0 2.8 1 1 1 2 2 2 1 Carbon-nitrogen hydrolase Mucin PF01456.12 EMR62368.1 - 0.08 12.7 15.8 0.13 12.0 11.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2407_C PF13373.1 EMR62369.1 - 2.4e-30 105.3 0.0 3.3e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EMR62369.1 - 4.2e-26 90.9 0.0 9.7e-26 89.8 0.0 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Ala_racemase_N PF01168.15 EMR62370.1 - 3.5e-37 128.0 0.1 4.8e-37 127.6 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain LSM14 PF12701.2 EMR62371.1 - 1.4e-33 114.5 0.0 2.4e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EMR62371.1 - 1.2e-20 73.9 0.7 2.3e-20 73.0 0.5 1.5 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 EMR62371.1 - 2.8e-05 23.9 0.0 6.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain LPP PF04728.8 EMR62371.1 - 0.3 10.9 3.1 4.9 7.0 0.4 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper NAD_binding_4 PF07993.7 EMR62372.1 - 1.7e-06 27.1 0.0 2.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein rRNA_proc-arch PF13234.1 EMR62373.1 - 5.1e-85 284.8 0.0 9.6e-85 283.9 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EMR62373.1 - 1.3e-58 197.2 0.7 1.3e-58 197.2 0.5 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EMR62373.1 - 5.5e-23 81.2 0.0 2.5e-22 79.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR62373.1 - 4.7e-09 35.9 0.0 1.1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR62373.1 - 0.0054 16.5 0.8 0.053 13.3 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EMR62373.1 - 0.024 13.5 0.0 0.087 11.7 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2514 PF10721.4 EMR62374.1 - 0.0068 16.1 3.4 0.012 15.3 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) Muted PF14942.1 EMR62374.1 - 0.011 15.6 1.4 0.015 15.2 0.5 1.5 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF2265 PF10023.4 EMR62374.1 - 0.022 13.9 4.5 0.028 13.5 3.1 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Nop14 PF04147.7 EMR62374.1 - 0.023 12.6 9.4 0.026 12.4 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family Tymo_45kd_70kd PF03251.8 EMR62374.1 - 0.097 11.3 1.0 0.14 10.8 0.7 1.1 1 0 0 1 1 1 0 Tymovirus 45/70Kd protein OmpH PF03938.9 EMR62374.1 - 0.26 11.1 11.3 0.52 10.2 7.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Presenilin PF01080.12 EMR62374.1 - 0.59 8.9 1.6 1.1 7.9 1.1 1.4 1 0 0 1 1 1 0 Presenilin TGF_beta_GS PF08515.7 EMR62374.1 - 0.75 9.1 3.5 1.6 8.0 2.4 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Spore_coat_CotO PF14153.1 EMR62374.1 - 2.2 7.6 10.3 0.14 11.6 2.8 1.9 2 0 0 2 2 2 0 Spore coat protein CotO Pox_Ag35 PF03286.9 EMR62374.1 - 2.6 7.5 15.0 0.19 11.2 0.7 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein BLVR PF06375.6 EMR62374.1 - 3.3 7.4 14.6 0.12 12.1 1.0 2.4 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) TAF4 PF05236.9 EMR62376.1 - 3.2e-08 33.1 5.4 0.00078 18.7 0.9 3.6 4 1 0 4 4 4 3 Transcription initiation factor TFIID component TAF4 family HicB PF05534.7 EMR62376.1 - 0.034 13.7 0.0 0.087 12.4 0.0 1.7 1 0 0 1 1 1 0 HicB family DUF202 PF02656.10 EMR62377.1 - 6.6e-14 51.8 3.8 6.6e-14 51.8 2.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Bax1-I PF01027.15 EMR62377.1 - 0.22 11.0 7.7 0.3 10.6 5.4 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Phageshock_PspG PF09583.5 EMR62377.1 - 0.32 11.0 0.3 0.32 11.0 0.2 2.4 3 0 0 3 3 3 0 Phage shock protein G (Phageshock_PspG) DUF2189 PF09955.4 EMR62377.1 - 0.73 9.7 7.4 0.12 12.3 1.7 1.8 1 1 2 3 3 3 0 Predicted integral membrane protein (DUF2189) NAD_binding_6 PF08030.7 EMR62378.1 - 1.2e-14 54.4 0.0 1.5e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMR62378.1 - 3e-13 49.9 13.8 7.6e-13 48.6 9.6 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EMR62378.1 - 3.4e-13 49.3 0.0 9.4e-13 47.9 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 EMR62378.1 - 0.031 14.8 0.0 7.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain SID-1_RNA_chan PF13965.1 EMR62378.1 - 0.59 8.2 7.7 0.43 8.6 4.5 1.3 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 RTA1 PF04479.8 EMR62379.1 - 1e-21 77.4 11.2 1.4e-21 77.0 7.8 1.1 1 0 0 1 1 1 1 RTA1 like protein TMEM125 PF15109.1 EMR62379.1 - 0.022 14.8 1.6 0.067 13.2 0.0 2.3 2 1 0 2 2 2 0 TMEM125 protein family DUF3446 PF11928.3 EMR62381.1 - 4.5 7.5 7.2 0.3 11.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) RRM_6 PF14259.1 EMR62382.1 - 2.4e-16 59.4 0.0 4.1e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR62382.1 - 2.9e-16 58.8 0.0 4.4e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR62382.1 - 6.7e-05 22.6 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fmp27_WPPW PF10359.4 EMR62382.1 - 0.054 11.9 0.9 0.064 11.6 0.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HrpA_pilin PF09589.5 EMR62382.1 - 0.58 10.5 2.4 0.9 9.9 1.7 1.2 1 0 0 1 1 1 0 HrpA pilus formation protein IncA PF04156.9 EMR62382.1 - 1.4 8.5 4.2 1.8 8.1 2.9 1.1 1 0 0 1 1 1 0 IncA protein Fez1 PF06818.10 EMR62384.1 - 3.6e-05 23.8 8.5 0.00035 20.6 8.5 4.1 2 1 2 4 4 4 2 Fez1 TBPIP PF07106.8 EMR62384.1 - 5.7e-05 22.7 46.9 0.00022 20.8 0.6 5.2 4 1 2 6 6 6 4 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG16 PF08614.6 EMR62384.1 - 0.0071 16.1 47.5 0.094 12.5 8.9 4.6 2 1 0 3 3 3 2 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EMR62384.1 - 0.013 14.6 8.1 0.044 12.9 0.1 3.3 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Antimicrobial_6 PF08036.6 EMR62384.1 - 0.047 13.4 3.8 24 4.7 0.0 4.0 4 0 0 4 4 4 0 Diapausin family of antimicrobial peptide HALZ PF02183.13 EMR62384.1 - 0.053 13.2 0.3 0.053 13.2 0.2 3.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF3573 PF12097.3 EMR62384.1 - 0.15 10.6 0.0 0.15 10.6 0.0 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3573) MbeD_MobD PF04899.7 EMR62384.1 - 0.5 10.3 13.5 0.059 13.2 1.0 4.6 5 0 0 5 5 5 0 MbeD/MobD like ADIP PF11559.3 EMR62384.1 - 5.4 6.9 53.0 0.5 10.2 1.0 5.9 3 1 3 6 6 6 0 Afadin- and alpha -actinin-Binding Vps53_N PF04100.7 EMR62384.1 - 6 5.5 28.0 0.027 13.2 6.6 3.5 2 1 3 5 5 5 0 Vps53-like, N-terminal Ion_trans PF00520.26 EMR62385.1 - 1.9e-05 24.0 3.0 3.2e-05 23.2 2.1 1.3 1 0 0 1 1 1 1 Ion transport protein Srg PF02118.16 EMR62385.1 - 0.0084 15.5 0.2 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 Srg family chemoreceptor Frigida PF07899.6 EMR62385.1 - 0.0097 14.7 0.4 0.022 13.5 0.0 1.6 2 0 0 2 2 2 1 Frigida-like protein Mto2_bdg PF12808.2 EMR62385.1 - 0.013 15.6 0.7 0.025 14.6 0.5 1.4 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_1 PF00170.16 EMR62385.1 - 0.081 12.8 0.2 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor ABC2_membrane PF01061.19 EMR62385.1 - 0.099 11.7 0.2 0.11 11.5 0.2 1.1 1 0 0 1 1 1 0 ABC-2 type transporter CTP_transf_2 PF01467.21 EMR62386.1 - 7.6e-22 78.0 0.0 1.2e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Fungal_trans PF04082.13 EMR62387.1 - 3.9e-11 42.3 0.4 7.7e-11 41.3 0.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain OPT PF03169.10 EMR62387.1 - 0.024 13.1 0.1 0.041 12.3 0.1 1.3 1 0 0 1 1 1 0 OPT oligopeptide transporter protein UnbV_ASPIC PF07593.7 EMR62387.1 - 0.094 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 ASPIC and UnbV DUF624 PF04854.9 EMR62387.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF624 Glyco_hydro_88 PF07470.8 EMR62388.1 - 1.7e-55 188.4 3.2 2e-55 188.1 2.2 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_9 PF00759.14 EMR62388.1 - 0.0026 16.7 1.8 0.0044 15.9 1.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF1680 PF07944.7 EMR62388.1 - 0.047 11.9 0.4 0.068 11.4 0.2 1.2 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) F-box-like PF12937.2 EMR62389.1 - 0.0036 17.0 0.1 0.0081 15.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like TAT_signal PF10518.4 EMR62389.1 - 0.081 12.9 2.6 0.18 11.8 1.8 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Methyltransf_23 PF13489.1 EMR62390.1 - 6.8e-21 74.6 0.0 1.1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR62390.1 - 2.9e-11 43.6 0.0 9.7e-11 42.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR62390.1 - 7e-09 36.2 0.0 2.3e-07 31.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR62390.1 - 7.2e-09 36.0 0.0 9.9e-08 32.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR62390.1 - 2e-08 33.9 0.0 3.7e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR62390.1 - 5.6e-06 25.6 0.1 0.0001 21.4 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMR62390.1 - 0.00029 21.1 0.0 0.001 19.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMR62390.1 - 0.001 18.1 0.1 0.0036 16.3 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.4 EMR62390.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EMR62390.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EMR62390.1 - 0.006 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.7 EMR62390.1 - 0.0086 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) FtsJ PF01728.14 EMR62390.1 - 0.013 15.4 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EMR62390.1 - 0.032 14.2 0.0 0.29 11.1 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain FAM181 PF15238.1 EMR62390.1 - 0.18 11.8 2.5 0.28 11.1 1.8 1.2 1 0 0 1 1 1 0 FAM181 HECT PF00632.20 EMR62391.1 - 2e-92 309.7 0.0 2.8e-92 309.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EMR62391.1 - 1.3e-31 108.0 21.9 1.2e-10 41.0 0.2 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EMR62391.1 - 1.6e-14 53.4 0.1 4.8e-14 51.9 0.1 1.8 1 0 0 1 1 1 1 C2 domain Tctex-1 PF03645.8 EMR62393.1 - 2.4e-32 110.8 0.0 2.8e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DHO_dh PF01180.16 EMR62395.1 - 8e-12 44.7 0.2 1.7e-08 33.8 0.1 2.8 2 1 0 2 2 2 2 Dihydroorotate dehydrogenase Oxidored_q6 PF01058.17 EMR62396.1 - 2.5e-22 78.8 0.0 3.7e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit F_actin_cap_B PF01115.12 EMR62397.1 - 0.054 12.6 1.5 0.058 12.5 1.1 1.0 1 0 0 1 1 1 0 F-actin capping protein, beta subunit Presenilin PF01080.12 EMR62397.1 - 4.5 5.9 7.1 4.8 5.9 4.9 1.0 1 0 0 1 1 1 0 Presenilin Hamartin PF04388.7 EMR62397.1 - 5.6 5.5 7.5 6.4 5.3 5.2 1.1 1 0 0 1 1 1 0 Hamartin protein DUF966 PF06136.8 EMR62397.1 - 8.3 5.7 7.8 9.5 5.5 5.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) NAD_binding_8 PF13450.1 EMR62399.1 - 1.1e-05 25.3 1.2 2.4e-05 24.2 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMR62399.1 - 1.3e-05 24.3 1.4 2.5e-05 23.3 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EMR62399.1 - 3.6e-05 23.0 3.4 0.02 13.9 0.5 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.9 EMR62399.1 - 0.00015 21.7 0.1 0.00029 20.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR62399.1 - 0.00033 19.6 1.1 0.00033 19.6 0.8 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMR62399.1 - 0.0023 16.6 0.2 1.1 7.8 0.1 2.3 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.17 EMR62399.1 - 0.0024 16.8 1.2 0.0034 16.2 0.2 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EMR62399.1 - 0.0074 14.7 0.5 0.013 14.0 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EMR62399.1 - 0.045 14.1 0.8 0.11 12.9 0.6 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR62399.1 - 0.054 12.4 0.5 7.6 5.3 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EMR62399.1 - 0.32 10.0 2.5 0.38 9.7 0.9 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EMR62399.1 - 0.6 9.6 2.5 0.55 9.7 0.3 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lumazine_bd_2 PF12893.2 EMR62400.1 - 0.074 13.5 0.1 0.19 12.2 0.0 1.7 2 0 0 2 2 2 0 Putative lumazine-binding DUF1992 PF09350.5 EMR62401.1 - 1.7e-25 88.6 0.2 6.3e-25 86.8 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) PEP_mutase PF13714.1 EMR62402.1 - 5e-51 173.2 2.6 5.8e-51 172.9 1.8 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EMR62402.1 - 5.1e-22 77.7 0.5 5.1e-21 74.4 0.8 1.9 2 0 0 2 2 2 1 Isocitrate lyase family DUF3433 PF11915.3 EMR62404.1 - 1e-23 83.3 9.8 4.2e-18 65.3 0.9 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) MFS_1 PF07690.11 EMR62405.1 - 1.2e-25 90.0 47.9 6.8e-24 84.2 32.4 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR62405.1 - 8.8e-22 77.0 19.9 1.2e-21 76.5 13.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3464 PF11947.3 EMR62405.1 - 0.39 10.1 2.4 1.4 8.3 1.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) AcetylCoA_hydro PF02550.10 EMR62406.1 - 6.7e-50 169.5 0.0 1.3e-49 168.6 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EMR62406.1 - 2.4e-37 127.9 0.0 3.6e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain 7TM_GPCR_Srd PF10317.4 EMR62407.1 - 0.029 13.3 3.1 0.047 12.6 2.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Bromodomain PF00439.20 EMR62408.1 - 2e-18 66.0 0.0 4.5e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain BTB PF00651.26 EMR62408.1 - 5.7e-10 39.1 0.0 4.3e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Neur_chan_memb PF02932.11 EMR62409.1 - 4.2 7.1 5.7 6.6 6.5 4.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAP30_Sin3_bdg PF13867.1 EMR62411.1 - 4.4e-12 45.6 0.5 1.8e-10 40.5 0.1 2.3 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 Mit_KHE1 PF10173.4 EMR62412.1 - 2.6e-60 203.4 0.2 4.1e-60 202.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related DUF588 PF04535.7 EMR62413.1 - 0.0017 17.9 0.4 0.0024 17.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF588) 7tm_1 PF00001.16 EMR62413.1 - 0.036 13.1 0.2 0.051 12.7 0.1 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) RDD PF06271.7 EMR62413.1 - 0.21 11.4 3.0 6.4 6.6 0.3 2.2 2 0 0 2 2 2 0 RDD family DUF4014 PF13198.1 EMR62413.1 - 0.31 11.4 1.9 0.74 10.2 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4014) PGG PF13962.1 EMR62413.1 - 2.4 7.8 6.4 0.49 10.0 1.7 1.8 2 0 0 2 2 2 0 Domain of unknown function BRO1 PF03097.13 EMR62414.1 - 6.6e-130 433.2 2.4 6.6e-130 433.2 1.7 2.0 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EMR62414.1 - 2e-94 315.8 16.1 5.3e-94 314.4 11.1 1.7 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF4407 PF14362.1 EMR62414.1 - 7.7 5.3 19.7 0.22 10.4 5.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Avl9 PF09794.4 EMR62415.1 - 1.8e-62 211.0 0.2 2.2e-36 125.1 0.0 2.2 1 1 1 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.4 EMR62415.1 - 0.033 13.4 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) PAS PF00989.19 EMR62416.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 PAS fold CTDII PF01556.13 EMR62417.1 - 6.2e-29 99.7 0.9 3.9e-22 77.9 0.1 3.4 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EMR62417.1 - 4e-23 80.9 3.0 7e-23 80.1 2.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EMR62417.1 - 7.5e-10 38.7 21.6 1.4e-09 37.8 15.0 1.5 1 0 0 1 1 1 1 DnaJ central domain SerH PF06873.6 EMR62417.1 - 0.063 11.8 7.0 0.093 11.3 4.8 1.1 1 0 0 1 1 1 0 Cell surface immobilisation antigen SerH FYVE PF01363.16 EMR62417.1 - 3.8 7.4 7.3 2.6 8.0 0.4 2.3 2 0 0 2 2 2 0 FYVE zinc finger Cullin PF00888.17 EMR62418.1 - 1.9e-202 673.9 12.4 2.4e-202 673.6 8.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EMR62418.1 - 5.3e-27 93.4 6.9 5.5e-27 93.3 2.2 2.8 3 0 0 3 3 3 1 Cullin protein neddylation domain Glyco_hydro_67M PF07488.7 EMR62419.1 - 3.3e-150 499.5 0.3 4.2e-150 499.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 EMR62419.1 - 4.3e-93 310.8 1.0 6.9e-93 310.1 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 EMR62419.1 - 4.2e-27 94.5 0.0 7.5e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 EMR62419.1 - 0.017 15.6 0.0 0.052 14.0 0.0 1.8 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 DUF2457 PF10446.4 EMR62420.1 - 0.033 12.9 15.0 0.043 12.5 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EMR62420.1 - 0.12 10.4 6.0 0.15 10.0 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein ANAPC15 PF15243.1 EMR62420.1 - 0.12 12.4 8.8 0.33 11.0 6.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 RXT2_N PF08595.6 EMR62420.1 - 2.6 7.8 5.5 4.2 7.1 3.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 EMR62420.1 - 8.3 5.9 11.0 14 5.1 7.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Glyco_hydro_88 PF07470.8 EMR62421.1 - 4.4e-37 127.8 1.6 5.3e-37 127.6 1.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Clp1 PF06807.9 EMR62422.1 - 5.6e-09 36.0 0.0 0.00055 19.7 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 AAA_17 PF13207.1 EMR62422.1 - 0.02 15.6 0.0 0.065 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Iso_dh PF00180.15 EMR62424.1 - 3e-80 269.7 0.0 3.5e-80 269.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CMD PF02627.15 EMR62425.1 - 0.0016 18.2 0.4 0.022 14.5 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family DUF3176 PF11374.3 EMR62426.1 - 6.7e-22 77.4 0.5 1.2e-21 76.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Pkinase PF00069.20 EMR62427.1 - 2e-68 230.3 0.0 3.3e-68 229.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR62427.1 - 8.9e-51 172.4 0.0 1.9e-50 171.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR62427.1 - 0.0095 14.9 0.0 0.033 13.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PAT1 PF09770.4 EMR62427.1 - 7 4.7 28.4 9.1 4.3 19.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF925 PF06042.6 EMR62428.1 - 1.7e-36 125.2 0.2 1.7e-35 121.9 0.1 1.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF925) Glyco_hydro_16 PF00722.16 EMR62429.1 - 5.8e-35 120.2 3.7 8.6e-35 119.6 2.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.11 EMR62430.1 - 5e-16 58.3 56.5 5e-16 58.3 39.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2819 PF10995.3 EMR62431.1 - 0.041 12.6 0.2 0.079 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2819) TrkH PF02386.11 EMR62432.1 - 3.3e-71 239.7 13.1 1.1e-65 221.5 4.4 3.0 2 1 0 2 2 2 2 Cation transport protein DUF805 PF05656.9 EMR62433.1 - 0.046 13.5 13.3 0.066 13.0 5.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF805) DUF4064 PF13273.1 EMR62433.1 - 0.3 11.2 6.1 19 5.4 2.8 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2721 PF11026.3 EMR62433.1 - 2.1 8.0 6.9 2.8 7.5 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) DNA_methylase PF00145.12 EMR62434.1 - 1.6e-56 191.8 0.0 1.5e-44 152.4 0.0 2.0 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Met_10 PF02475.11 EMR62434.1 - 0.0053 16.3 0.0 0.011 15.3 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_2 PF00891.13 EMR62435.1 - 4.3e-29 101.4 0.0 1.7e-28 99.4 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase p450 PF00067.17 EMR62436.1 - 5e-21 74.7 0.0 8.1e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.17 EMR62437.1 - 2.2e-06 27.1 0.0 6.9e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR62437.1 - 5.5e-06 26.2 0.0 0.00023 21.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FleQ PF06490.6 EMR62437.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ AA_permease_2 PF13520.1 EMR62438.1 - 1.1e-37 129.6 51.8 1.4e-37 129.2 35.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMR62438.1 - 3e-17 62.1 49.9 4.7e-17 61.5 34.6 1.2 1 0 0 1 1 1 1 Amino acid permease NmrA PF05368.8 EMR62440.1 - 5.5e-12 45.4 0.0 8.6e-12 44.7 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR62440.1 - 3.6e-11 43.4 0.0 5.4e-11 42.8 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Myc_N PF01056.13 EMR62441.1 - 2.1 7.4 9.4 4.2 6.4 6.5 1.4 1 0 0 1 1 1 0 Myc amino-terminal region DNA_pol_phi PF04931.8 EMR62441.1 - 2.8 5.5 4.5 3.7 5.1 3.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi GST_N_2 PF13409.1 EMR62442.1 - 7.6e-15 54.6 0.0 1.6e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR62442.1 - 2.6e-07 30.4 0.0 1.7e-06 27.8 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMR62442.1 - 0.0055 16.8 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMR62442.1 - 0.0063 16.9 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ATP-grasp_2 PF08442.5 EMR62444.1 - 9e-07 28.4 0.0 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain MFS_1 PF07690.11 EMR62445.1 - 7.9e-11 41.2 20.6 7.9e-11 41.2 14.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Citrate_synt PF00285.16 EMR62446.1 - 5.5e-19 68.1 0.0 1.5e-16 60.1 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 EMR62446.1 - 6.9e-18 64.9 0.0 2.2e-17 63.3 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 EMR62446.1 - 4.7e-14 52.2 0.3 9.1e-14 51.3 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EMR62446.1 - 5.9e-05 22.6 0.2 0.0018 17.9 0.0 2.6 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CDH PF02611.10 EMR62447.1 - 0.019 14.2 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase Zn_clus PF00172.13 EMR62448.1 - 0.00017 21.4 6.5 0.00041 20.1 4.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.3 EMR62448.1 - 0.087 12.5 4.1 0.14 11.8 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Med3 PF11593.3 EMR62448.1 - 0.27 10.4 4.0 16 4.5 2.5 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Herpes_capsid PF06112.6 EMR62448.1 - 4 7.4 5.3 50 3.9 0.0 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Hexokinase_1 PF00349.16 EMR62449.1 - 0.05 12.9 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Hexokinase Cu-oxidase_2 PF07731.9 EMR62450.1 - 1.4e-36 125.0 1.0 6.4e-36 122.9 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EMR62450.1 - 4.4e-29 101.4 0.0 1.2e-28 99.9 0.0 1.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EMR62450.1 - 1.5e-25 89.2 0.8 3.5e-23 81.5 0.3 2.8 2 0 0 2 2 2 2 Multicopper oxidase Hexapep PF00132.19 EMR62451.1 - 1.6e-07 30.4 0.2 0.0003 20.1 0.0 2.6 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) DMP1 PF07263.6 EMR62451.1 - 0.022 13.4 2.8 0.028 13.1 2.0 1.0 1 0 0 1 1 1 0 Dentin matrix protein 1 (DMP1) Hexapep_2 PF14602.1 EMR62451.1 - 0.056 13.0 3.8 7.4 6.2 1.4 3.6 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase zf-C2H2_4 PF13894.1 EMR62452.1 - 2.8e-06 27.2 17.5 0.0032 17.6 2.0 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMR62452.1 - 2.6e-05 24.3 15.3 0.00078 19.6 1.3 3.3 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMR62452.1 - 0.002 18.3 14.4 0.0038 17.4 4.6 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EMR62452.1 - 0.013 15.4 1.1 0.044 13.6 0.8 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.2 EMR62452.1 - 0.022 14.9 1.6 0.061 13.5 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PyrI_C PF02748.10 EMR62452.1 - 0.039 13.3 1.9 0.082 12.3 1.3 1.5 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.3 EMR62452.1 - 0.067 13.3 4.6 0.12 12.6 0.5 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EMR62452.1 - 0.78 9.9 7.5 2.5 8.3 5.2 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Meth_synt_2 PF01717.13 EMR62453.1 - 5.2e-143 475.8 0.0 3.5e-138 460.0 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EMR62453.1 - 3.2e-122 407.6 0.1 1.4e-109 366.1 0.0 3.3 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Alpha_L_fucos PF01120.12 EMR62453.1 - 0.094 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-fucosidase Tudor-knot PF11717.3 EMR62454.1 - 2.5e-09 36.6 0.0 4.4e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EMR62454.1 - 0.018 14.7 0.1 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RAP1 PF07218.6 EMR62455.1 - 0.12 10.5 1.0 0.15 10.1 0.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Abhydrolase_2 PF02230.11 EMR62456.1 - 5.8e-24 84.7 0.0 4.4e-23 81.8 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EMR62456.1 - 7.4e-05 22.5 0.0 0.00016 21.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR62456.1 - 0.00013 21.2 0.0 0.00027 20.2 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMR62456.1 - 0.00028 20.8 2.2 0.047 13.5 1.5 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EMR62456.1 - 0.00079 18.7 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase FSH1 PF03959.8 EMR62456.1 - 0.002 17.6 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EMR62456.1 - 0.0081 15.7 0.0 3.9 6.9 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold CENP-Q PF13094.1 EMR62457.1 - 1.2e-25 90.4 0.3 2.3e-24 86.2 0.0 2.7 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Cnl2_NKP2 PF09447.5 EMR62458.1 - 5.1e-23 80.5 1.5 1.2e-22 79.3 1.1 1.7 1 0 0 1 1 1 1 Cnl2/NKP2 family protein Syntaxin_2 PF14523.1 EMR62458.1 - 0.0072 16.3 2.7 0.35 10.9 0.0 2.2 2 0 0 2 2 2 1 Syntaxin-like protein DUF972 PF06156.8 EMR62458.1 - 0.016 15.5 2.3 3.3 8.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Fzo_mitofusin PF04799.8 EMR62458.1 - 0.05 12.9 3.9 1.5 8.2 0.3 2.1 2 0 0 2 2 2 0 fzo-like conserved region Hom_end_hint PF05203.11 EMR62458.1 - 0.059 13.0 1.2 0.073 12.7 0.8 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Mnd1 PF03962.10 EMR62458.1 - 0.066 12.8 4.9 0.7 9.5 0.1 2.0 2 0 0 2 2 2 0 Mnd1 family V_ATPase_I PF01496.14 EMR62458.1 - 0.07 10.9 2.7 0.08 10.7 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mt_ATP-synt_B PF05405.9 EMR62458.1 - 0.12 11.8 1.9 0.94 8.9 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4613 PF15390.1 EMR62458.1 - 0.38 8.8 2.4 0.44 8.6 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) LXG PF04740.7 EMR62458.1 - 0.63 9.7 5.5 3.4 7.4 0.2 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily TMCO5 PF14992.1 EMR62458.1 - 0.84 8.7 7.5 0.58 9.2 0.2 2.2 2 0 0 2 2 2 0 TMCO5 family DUF572 PF04502.8 EMR62458.1 - 1 8.4 6.8 4 6.5 4.8 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF572) zf-C4H2 PF10146.4 EMR62458.1 - 1.8 8.5 6.2 3.6 7.5 4.2 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein ANAPC15 PF15243.1 EMR62458.1 - 1.8 8.7 6.9 4.7 7.3 0.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Steroid_dh PF02544.11 EMR62459.1 - 1.8e-22 79.7 0.8 7.7e-22 77.6 0.6 2.0 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EMR62459.1 - 4.8e-07 29.3 0.3 9.7e-07 28.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) HET PF06985.6 EMR62460.1 - 1.1e-17 64.4 0.0 4.7e-17 62.4 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Gly_transf_sug PF04488.10 EMR62461.1 - 4e-10 40.0 0.0 1.1e-09 38.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EMR62461.1 - 7.3e-07 28.6 0.0 1.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 EMR62461.1 - 0.013 14.0 0.0 0.018 13.5 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Spt20 PF12090.3 EMR62463.1 - 0.00056 19.2 0.1 0.00056 19.2 0.1 6.8 4 2 1 5 5 5 2 Spt20 family NmrA PF05368.8 EMR62464.1 - 2.5e-33 115.2 0.0 3.3e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR62464.1 - 6.5e-12 45.8 0.0 8.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR62464.1 - 6.4e-07 29.0 0.0 1e-06 28.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR62464.1 - 5.9e-06 25.1 0.0 8.1e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EMR62464.1 - 0.00015 21.4 0.2 0.00022 20.9 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EMR62464.1 - 0.00086 18.3 0.0 0.025 13.5 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EMR62464.1 - 0.0011 18.8 0.2 0.0022 17.9 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.12 EMR62464.1 - 0.11 12.8 0.1 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ATG27 PF09451.5 EMR62465.1 - 1.5e-71 240.8 0.0 2.1e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EMR62465.1 - 0.00051 19.8 0.3 0.68 9.6 0.1 3.1 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat Ribosomal_L30 PF00327.15 EMR62466.1 - 2e-16 59.2 0.1 2.6e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MRG PF05712.8 EMR62467.1 - 9.5e-57 191.0 0.0 1.4e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 MRG BCDHK_Adom3 PF10436.4 EMR62468.1 - 1.9e-43 147.8 0.0 2.8e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EMR62468.1 - 6.1e-16 58.1 0.0 2.7e-15 56.0 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Chitin_synth_2 PF03142.10 EMR62469.1 - 7e-253 839.8 1.0 1e-252 839.2 0.7 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EMR62469.1 - 3.8e-167 557.3 0.0 5.2e-167 556.9 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 EMR62469.1 - 1.9e-17 62.7 0.4 1.4e-16 59.9 0.3 2.3 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 EMR62469.1 - 1.2e-16 60.2 0.1 1.5e-11 43.9 0.1 3.2 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 EMR62469.1 - 1.6e-13 50.9 0.1 4e-10 39.8 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMR62469.1 - 1.6e-13 50.7 7.6 1.6e-13 50.7 5.3 2.4 2 1 0 2 2 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EMR62469.1 - 3.6e-05 23.5 0.0 0.0071 16.0 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.1 EMR62469.1 - 0.0024 17.9 0.2 0.0068 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMR62469.1 - 0.0024 17.9 0.4 0.04 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Glyco_transf_21 PF13506.1 EMR62469.1 - 0.0035 16.6 0.1 0.04 13.2 0.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 21 AAA_25 PF13481.1 EMR62469.1 - 0.017 14.5 0.2 0.19 11.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EMR62469.1 - 0.017 14.6 0.2 0.1 12.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 EMR62469.1 - 0.1 12.2 0.2 0.53 9.9 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EMR62469.1 - 0.12 12.6 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMR62469.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.5 EMR62469.1 - 0.47 9.6 1.3 1.2 8.2 0.3 2.2 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Fungal_trans PF04082.13 EMR62470.1 - 5.1e-19 68.1 0.0 9.9e-19 67.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR62470.1 - 1.4e-09 37.7 10.4 2.1e-09 37.1 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XkdN PF08890.6 EMR62470.1 - 0.13 12.0 0.2 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Phage XkdN-like protein Chitin_synth_2 PF03142.10 EMR62472.1 - 4.9e-229 761.1 0.0 7.1e-229 760.5 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EMR62472.1 - 1.6e-46 158.7 0.0 6.3e-46 156.7 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EMR62472.1 - 2.8e-21 75.0 0.0 3.3e-11 42.8 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EMR62472.1 - 2.3e-16 60.0 2.9 2.3e-16 60.0 2.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 EMR62472.1 - 1.5e-14 53.5 0.8 1.8e-13 50.0 0.6 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 EMR62472.1 - 1.6e-14 54.2 0.0 7.9e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EMR62472.1 - 4.5e-06 26.0 0.0 2.1e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EMR62472.1 - 0.00092 18.9 0.0 0.06 13.0 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Jiv90 PF14901.1 EMR62472.1 - 0.096 12.6 0.8 4.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone DASH_Ask1 PF08655.5 EMR62473.1 - 1.2e-32 111.4 0.1 2e-32 110.7 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 Gly_rich PF12810.2 EMR62473.1 - 0.46 10.0 6.2 0.37 10.3 1.6 2.1 2 0 0 2 2 2 0 Glycine rich protein DUF663 PF04950.7 EMR62474.1 - 3.1e-82 275.8 0.0 3.1e-82 275.8 0.0 1.9 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EMR62474.1 - 3.7e-27 93.6 0.0 4.5e-26 90.2 0.0 2.4 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA_22 PF13401.1 EMR62474.1 - 6.8e-06 26.2 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EMR62474.1 - 1.1e-05 24.9 0.8 0.0033 16.8 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EMR62474.1 - 1.2e-05 25.4 0.0 3.6e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 EMR62474.1 - 0.00039 20.3 0.0 0.00095 19.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EMR62474.1 - 0.0005 20.2 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EMR62474.1 - 0.00054 19.6 0.0 0.0016 18.1 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 EMR62474.1 - 0.00056 19.6 0.1 0.0017 18.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 EMR62474.1 - 0.00059 20.1 0.3 0.0029 17.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 EMR62474.1 - 0.00085 19.8 0.1 0.004 17.6 0.0 2.2 2 0 0 2 2 1 1 Miro-like protein PduV-EutP PF10662.4 EMR62474.1 - 0.0012 18.2 0.0 0.0031 17.0 0.0 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EMR62474.1 - 0.0019 17.9 0.0 0.0072 16.0 0.0 2.0 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EMR62474.1 - 0.0021 18.8 0.0 0.0021 18.8 0.0 4.9 4 1 2 6 6 3 1 AAA domain AAA_25 PF13481.1 EMR62474.1 - 0.0025 17.2 0.0 0.0062 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMR62474.1 - 0.0032 17.3 0.0 0.008 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMR62474.1 - 0.0043 16.9 0.4 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMR62474.1 - 0.006 16.8 0.0 0.006 16.8 0.0 3.7 4 1 0 4 4 2 1 AAA domain RNA_helicase PF00910.17 EMR62474.1 - 0.0096 16.0 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.17 EMR62474.1 - 0.011 14.6 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 EMR62474.1 - 0.012 15.3 0.2 0.024 14.3 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.14 EMR62474.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EMR62474.1 - 0.014 15.0 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EMR62474.1 - 0.016 14.6 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 EMR62474.1 - 0.045 12.9 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EMR62474.1 - 0.076 12.7 0.1 0.26 10.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EMR62474.1 - 3.7 7.0 8.2 2.1 7.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain p450 PF00067.17 EMR62475.1 - 3.1e-44 151.2 0.0 3.7e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.1 EMR62477.1 - 2.3e-13 50.5 0.1 1e-12 48.4 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR62477.1 - 3.4e-05 23.2 0.0 5.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EMR62477.1 - 0.00058 19.8 0.2 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EMR62477.1 - 0.028 13.9 0.1 0.053 13.0 0.1 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.16 EMR62477.1 - 0.12 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Inhibitor_I9 PF05922.11 EMR62478.1 - 4.4e-15 56.0 0.1 4.8e-15 55.8 0.1 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ribosom_S12_S23 PF00164.20 EMR62479.1 - 1.8e-42 143.6 0.5 2.1e-42 143.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acyl-CoA_dh_N PF02771.11 EMR62480.1 - 3.6e-29 101.6 0.1 6.4e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EMR62480.1 - 5.5e-16 57.8 0.1 1.1e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EMR62480.1 - 0.014 15.4 0.2 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EMR62480.1 - 0.14 11.4 0.2 0.65 9.3 0.1 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PLDc_N PF13396.1 EMR62481.1 - 3.1e-13 49.1 4.5 3.1e-13 49.1 3.1 1.7 1 1 0 1 1 1 1 Phospholipase_D-nuclease N-terminal BCD PF15461.1 EMR62481.1 - 0.045 13.1 2.0 0.049 13.0 1.4 1.1 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase DUF3784 PF12650.2 EMR62481.1 - 0.057 13.3 2.1 0.095 12.6 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) DUF3169 PF11368.3 EMR62481.1 - 0.066 12.4 0.3 0.089 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) O-antigen_lig PF13425.1 EMR62481.1 - 0.085 12.8 1.0 0.15 12.0 0.7 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein HAP PF03866.8 EMR62481.1 - 0.11 12.3 0.3 0.18 11.5 0.2 1.5 1 1 0 1 1 1 0 Hydrophobic abundant protein (HAP) DUF3951 PF13131.1 EMR62481.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) DUF3278 PF11683.3 EMR62481.1 - 0.15 12.0 0.6 0.19 11.7 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DUF2207 PF09972.4 EMR62481.1 - 0.16 10.5 0.8 0.19 10.3 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF606 PF04657.8 EMR62481.1 - 0.23 11.5 3.8 0.21 11.6 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF606 Glucos_trans_II PF14264.1 EMR62481.1 - 0.33 9.8 4.0 0.19 10.6 1.8 1.3 1 1 0 1 1 1 0 Glucosyl transferase GtrII DUF4199 PF13858.1 EMR62481.1 - 0.88 9.4 4.6 0.12 12.2 0.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF805 PF05656.9 EMR62481.1 - 4.2 7.2 5.8 19 5.1 4.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF805) MpPF26 PF07666.6 EMR62481.1 - 9 6.2 8.6 11 5.8 6.0 1.4 1 1 0 1 1 1 0 M penetrans paralogue family 26 Glyco_hydro_18 PF00704.23 EMR62482.1 - 5.2e-77 259.6 7.5 7.5e-77 259.0 5.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 adh_short PF00106.20 EMR62483.1 - 1.4e-24 86.8 1.1 1.8e-24 86.5 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR62483.1 - 1.9e-24 86.7 0.0 2.4e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR62483.1 - 2.7e-09 36.9 0.3 4.6e-09 36.2 0.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR62483.1 - 0.011 15.1 0.1 0.016 14.6 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR62483.1 - 0.061 12.0 0.0 0.091 11.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Esterase PF00756.15 EMR62484.1 - 1e-05 25.1 0.0 1.5e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EMR62484.1 - 0.00077 18.7 0.0 0.0016 17.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMR62484.1 - 0.0024 17.8 0.1 0.0032 17.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR62484.1 - 0.0029 17.3 0.1 0.0044 16.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMR62484.1 - 0.0034 16.8 0.0 0.008 15.6 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 EMR62484.1 - 0.0063 15.7 0.2 0.017 14.4 0.1 1.7 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 EMR62484.1 - 0.054 13.0 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ribosomal_L7Ae PF01248.21 EMR62485.1 - 2.3e-21 75.1 0.6 3.7e-21 74.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EMR62485.1 - 0.0062 16.3 0.0 0.0093 15.8 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 Pam17 PF08566.5 EMR62485.1 - 0.094 12.4 0.0 0.23 11.1 0.0 1.6 2 1 0 2 2 2 0 Mitochondrial import protein Pam17 MFS_1 PF07690.11 EMR62486.1 - 5.8e-21 74.5 52.3 1e-12 47.4 13.8 3.1 2 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR62486.1 - 1.9e-08 32.9 21.6 2.7e-08 32.5 15.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF872 PF05915.7 EMR62486.1 - 2.1 8.2 4.9 1.3 8.9 0.5 2.7 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) AMP-binding PF00501.23 EMR62487.1 - 3.4e-80 269.4 0.0 5.8e-80 268.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EMR62487.1 - 2.7e-78 262.9 0.0 8.5e-78 261.3 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EMR62487.1 - 4.5e-47 160.0 0.0 5e-45 153.3 0.0 3.3 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 EMR62487.1 - 7.9e-47 160.1 0.1 1.5e-46 159.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EMR62487.1 - 1.2e-46 159.2 0.0 2.1e-46 158.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EMR62487.1 - 1.4e-43 148.8 0.0 2.7e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 EMR62487.1 - 1.5e-40 138.8 0.1 5.1e-37 127.3 0.0 3.7 3 0 0 3 3 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 EMR62487.1 - 4.1e-33 114.3 0.0 9.6e-33 113.1 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EMR62487.1 - 2.8e-31 107.8 0.0 9.6e-31 106.0 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EMR62487.1 - 6.9e-18 64.6 0.1 8e-10 38.8 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EMR62487.1 - 2.7e-17 63.0 0.0 1e-16 61.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 EMR62487.1 - 3.2e-12 46.6 0.0 9.6e-12 45.0 0.0 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain Epimerase PF01370.16 EMR62487.1 - 3.2e-12 46.3 0.0 5.1e-08 32.6 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 EMR62487.1 - 1.2e-11 44.6 0.0 3.8e-11 42.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR62487.1 - 1.1e-10 41.3 0.0 2.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR62487.1 - 3.6e-09 36.9 0.0 1.3e-08 35.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR62487.1 - 2.3e-07 31.3 0.0 1.9e-06 28.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain 3Beta_HSD PF01073.14 EMR62487.1 - 1.8e-06 26.9 0.0 1.3e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.4 EMR62487.1 - 1.6e-05 24.4 0.0 3.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Thiolase_N PF00108.18 EMR62487.1 - 2.1e-05 23.6 0.0 4.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EMR62487.1 - 0.00059 19.0 0.0 0.0016 17.6 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NAD_binding_10 PF13460.1 EMR62487.1 - 0.0012 18.8 0.0 0.73 9.8 0.0 3.1 2 0 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EMR62487.1 - 0.029 13.2 0.0 7.9 5.2 0.0 2.7 2 1 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.8 EMR62487.1 - 0.031 13.5 0.0 3.6 6.7 0.0 2.4 2 0 0 2 2 2 0 NmrA-like family Saccharop_dh PF03435.13 EMR62487.1 - 0.081 11.8 0.0 9.2 5.1 0.0 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase PCMT PF01135.14 EMR62487.1 - 0.23 10.9 0.0 0.91 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) EF-hand_1 PF00036.27 EMR62488.1 - 8.2e-15 52.9 7.2 0.00011 21.2 0.3 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EMR62488.1 - 2.9e-14 52.9 0.8 1.4e-08 34.7 0.0 2.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EMR62488.1 - 7.9e-14 50.2 5.7 6.8e-05 22.4 0.3 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 EMR62488.1 - 6.1e-12 44.9 2.9 1.5e-07 30.9 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMR62488.1 - 2.3e-07 29.8 4.8 0.055 12.8 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EMR62488.1 - 0.00086 19.1 0.0 0.0096 15.8 0.0 2.5 2 2 2 4 4 4 1 EF-hand domain Caleosin PF05042.8 EMR62488.1 - 0.017 14.7 0.0 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 Caleosin related protein EF-hand_4 PF12763.2 EMR62488.1 - 0.052 13.2 0.1 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand FAD_binding_3 PF01494.14 EMR62489.1 - 2.4e-21 76.1 0.3 1.9e-12 46.9 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMR62489.1 - 2.6e-06 27.3 0.0 6.4e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR62489.1 - 3.1e-05 23.0 0.0 0.12 11.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR62489.1 - 7.6e-05 23.0 0.1 0.1 12.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMR62489.1 - 0.0018 17.4 0.0 0.023 13.7 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EMR62489.1 - 0.0056 15.5 0.0 0.014 14.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EMR62489.1 - 0.0056 16.7 0.1 0.054 13.5 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR62489.1 - 0.0076 16.1 0.0 0.027 14.3 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EMR62489.1 - 0.044 12.6 0.0 0.076 11.8 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.12 EMR62489.1 - 0.063 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 EMR62489.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Transketolase_N PF00456.16 EMR62490.1 - 1.2e-115 385.8 0.0 3.3e-115 384.4 0.0 1.6 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EMR62490.1 - 2.8e-36 124.6 0.0 5.7e-36 123.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 EMR62490.1 - 1.2e-07 30.9 0.2 2.1e-05 23.6 0.0 2.5 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 EMR62490.1 - 1.7e-06 27.9 0.0 3.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 EMR62490.1 - 0.00012 20.9 0.3 0.00019 20.2 0.2 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component GSHPx PF00255.14 EMR62490.1 - 0.001 18.4 0.1 0.099 12.0 0.0 2.5 2 0 0 2 2 2 1 Glutathione peroxidase SnoaL_2 PF12680.2 EMR62490.1 - 0.032 14.6 0.0 0.18 12.2 0.0 2.3 2 0 0 2 2 2 0 SnoaL-like domain NACHT PF05729.7 EMR62491.1 - 1.9e-06 27.6 0.1 6.5e-06 25.8 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EMR62491.1 - 1.9e-06 28.0 0.0 1.3e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMR62491.1 - 0.0048 16.9 3.2 0.013 15.5 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EMR62491.1 - 0.0085 16.9 0.8 0.064 14.0 0.0 2.8 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 EMR62491.1 - 0.0096 16.2 0.1 0.083 13.1 0.0 2.2 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.17 EMR62491.1 - 0.011 14.6 0.0 0.038 12.8 0.0 1.9 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 EMR62491.1 - 0.014 15.6 0.1 5.7 7.1 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EMR62491.1 - 0.02 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EMR62491.1 - 0.025 14.2 0.0 0.071 12.7 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 EMR62491.1 - 0.033 13.6 0.3 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 EMR62491.1 - 0.036 13.6 0.1 0.092 12.2 0.1 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EMR62491.1 - 0.039 13.1 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EMR62491.1 - 0.046 13.8 0.1 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EMR62491.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMR62491.1 - 0.077 13.3 0.1 0.3 11.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 EMR62491.1 - 0.079 13.2 0.3 3.1 8.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain Phage_GPO PF05929.6 EMR62491.1 - 0.95 8.6 3.9 2 7.6 0.3 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DivIC PF04977.10 EMR62492.1 - 0.024 14.1 0.3 0.058 12.8 0.2 1.6 1 0 0 1 1 1 0 Septum formation initiator Mto2_bdg PF12808.2 EMR62492.1 - 0.026 14.6 3.5 0.064 13.3 2.4 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region APH PF01636.18 EMR62493.1 - 1.1e-19 71.0 0.1 1.1e-19 71.0 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Nucleoplasmin PF03066.10 EMR62493.1 - 4.2 6.8 9.6 7.2 6.1 6.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin OCD_Mu_crystall PF02423.10 EMR62494.1 - 1.5e-11 43.6 9.4 2e-11 43.2 0.0 2.5 3 0 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EMR62494.1 - 0.0036 17.3 0.1 0.07 13.2 0.0 2.4 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Ribosomal_60s PF00428.14 EMR62494.1 - 0.0085 16.4 2.4 0.023 15.0 1.3 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein Mucin PF01456.12 EMR62494.1 - 0.1 12.3 8.6 0.22 11.2 5.9 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Corona_nucleoca PF00937.13 EMR62494.1 - 3.6 6.4 12.0 5.4 5.8 8.3 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Thiolase_N PF00108.18 EMR62495.1 - 3.6e-78 262.2 1.0 5.2e-78 261.6 0.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMR62495.1 - 5.3e-43 145.3 0.1 1e-42 144.4 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMR62495.1 - 0.017 14.6 2.0 0.047 13.1 0.5 2.3 2 1 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain LMWSLP_N PF12211.3 EMR62495.1 - 0.023 14.5 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Low molecular weight S layer protein N terminal ACP_syn_III_C PF08541.5 EMR62495.1 - 0.031 14.3 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal An_peroxidase PF03098.10 EMR62496.1 - 6.9e-91 305.2 0.0 9.4e-89 298.1 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EMR62496.1 - 4.3e-05 22.2 0.0 0.00011 20.9 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 DEAD PF00270.24 EMR62497.1 - 2.6e-35 121.4 0.0 5.7e-35 120.2 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EMR62497.1 - 3.1e-18 65.0 0.0 6.1e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EMR62497.1 - 6.3e-18 64.4 0.0 1.4e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR62497.1 - 0.0027 17.5 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EMR62497.1 - 0.018 14.7 0.0 0.075 12.7 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain Fungal_trans PF04082.13 EMR62498.1 - 2.6e-13 49.4 0.0 5.6e-13 48.3 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2867 PF11066.3 EMR62498.1 - 0.078 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2867) DUF2235 PF09994.4 EMR62499.1 - 4.9e-75 252.4 0.0 2.8e-74 249.9 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EMR62499.1 - 0.084 12.6 0.0 0.67 9.6 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Cuticle_2 PF08184.6 EMR62499.1 - 0.13 12.1 1.3 0.28 10.9 0.9 1.6 1 0 0 1 1 1 0 Cuticle protein 7 isoform family Phage_CRI PF05144.9 EMR62500.1 - 0.052 12.6 0.1 0.095 11.7 0.1 1.3 1 0 0 1 1 1 0 Phage replication protein CRI MFS_1 PF07690.11 EMR62502.1 - 1.5e-42 145.5 42.9 1.5e-42 145.5 29.7 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR62502.1 - 6.6e-14 51.0 18.8 1.3e-13 50.0 13.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.20 EMR62503.1 - 0.089 11.9 0.0 0.17 10.9 0.0 1.6 1 1 1 2 2 2 0 Protein kinase domain DIOX_N PF14226.1 EMR62504.1 - 1.2e-28 99.9 0.0 2.2e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMR62504.1 - 3.5e-17 62.5 0.0 5.7e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GFO_IDH_MocA PF01408.17 EMR62505.1 - 7.9e-21 74.7 0.0 1.7e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EMR62505.1 - 9.7e-07 29.1 0.0 2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.12 EMR62505.1 - 0.0013 18.5 0.0 0.0037 17.0 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain MFS_1 PF07690.11 EMR62506.1 - 9.8e-20 70.5 20.3 9.8e-20 70.5 14.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 EMR62507.1 - 0.00013 21.9 0.0 0.00027 20.8 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMR62507.1 - 0.00092 18.8 0.6 0.014 14.9 0.0 2.9 2 2 1 3 3 3 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EMR62507.1 - 0.0055 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EMR62507.1 - 0.014 14.6 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ATP_bind_3 PF01171.15 EMR62508.1 - 3.5e-10 39.6 0.0 5.2e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EMR62508.1 - 0.0009 19.5 0.0 0.0022 18.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 EMR62508.1 - 0.0015 17.9 0.5 0.0015 17.9 0.3 2.2 3 0 0 3 3 3 1 RecR protein Birna_VP4 PF01768.11 EMR62508.1 - 0.12 11.4 0.3 0.27 10.2 0.1 1.6 2 0 0 2 2 2 0 Birnavirus VP4 protein Mito_carr PF00153.22 EMR62509.1 - 1.2e-56 188.3 2.8 6.5e-20 70.6 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EMR62509.1 - 0.01 15.8 0.9 0.044 13.8 0.2 2.6 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family DUF3147 PF11345.3 EMR62509.1 - 0.044 13.8 0.2 0.87 9.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3147) Band_7 PF01145.20 EMR62510.1 - 7.9e-28 97.5 3.4 1.5e-27 96.6 2.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family F-box-like PF12937.2 EMR62511.1 - 4.8e-05 22.9 0.1 0.00014 21.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMR62511.1 - 0.0011 18.6 0.6 0.0047 16.5 0.3 2.2 2 0 0 2 2 2 1 F-box domain p450 PF00067.17 EMR62512.1 - 8.5e-24 83.8 0.0 2.5e-22 79.0 0.0 2.7 1 1 0 1 1 1 1 Cytochrome P450 DUF3732 PF12532.3 EMR62512.1 - 0.021 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) ADH_zinc_N PF00107.21 EMR62513.1 - 6.7e-09 35.3 0.0 1.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR62513.1 - 1.9e-08 34.0 0.2 1.1e-07 31.5 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Nup96 PF12110.3 EMR62514.1 - 3.9e-89 298.6 0.3 5.4e-89 298.1 0.2 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EMR62514.1 - 7.5e-45 152.2 0.0 1.2e-44 151.4 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EMR62514.1 - 5.5e-21 74.9 364.2 1.7e-10 41.1 33.0 10.0 3 3 6 9 9 9 6 Nucleoporin FG repeat region ORC6 PF05460.8 EMR62514.1 - 0.054 12.5 4.5 0.14 11.2 3.1 1.7 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FAD_binding_4 PF01565.18 EMR62515.1 - 8.4e-16 57.7 0.7 1.4e-15 56.9 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Mito_carr PF00153.22 EMR62516.1 - 1.1e-55 185.2 2.9 6.4e-20 70.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 EMR62517.1 - 4.3e-21 74.4 3.1 4.4e-08 32.7 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2077 PF09850.4 EMR62517.1 - 0.12 11.7 1.1 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF2413 PF10310.4 EMR62517.1 - 0.27 10.0 6.2 0.058 12.2 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) APH PF01636.18 EMR62518.1 - 9.8e-08 32.0 0.1 0.00026 20.8 0.2 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMR62518.1 - 4.6e-06 26.3 0.0 0.0025 17.3 0.0 2.1 1 1 1 2 2 2 2 Choline/ethanolamine kinase Pkinase PF00069.20 EMR62518.1 - 0.001 18.3 0.1 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.6 EMR62518.1 - 0.0073 15.5 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.9 EMR62518.1 - 0.012 14.6 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M28 PF04389.12 EMR62519.1 - 5e-38 130.6 0.0 6.7e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Pro_CA PF00484.14 EMR62520.1 - 3e-44 150.7 0.2 3.5e-44 150.4 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase ENTH PF01417.15 EMR62521.1 - 2.9e-48 162.8 0.1 4.5e-48 162.2 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EMR62521.1 - 0.0018 17.0 0.0 0.0026 16.4 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.1 EMR62521.1 - 0.012 14.9 0.1 0.021 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) DUF1510 PF07423.6 EMR62521.1 - 0.26 10.6 5.9 1.5 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) AAA PF00004.24 EMR62523.1 - 1.5e-10 41.3 0.0 4.8e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMR62523.1 - 3.2e-05 23.9 0.1 6.6e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMR62523.1 - 0.00045 20.3 0.0 0.00091 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMR62523.1 - 0.0019 17.9 0.0 0.0068 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EMR62523.1 - 0.026 14.2 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 EMR62523.1 - 0.03 13.7 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.7 EMR62523.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus P5CR_dimer PF14748.1 EMR62524.1 - 1.7e-36 124.4 2.6 1.7e-36 124.4 1.8 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EMR62524.1 - 3.9e-19 68.8 0.6 3.9e-19 68.8 0.4 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EMR62524.1 - 2.4e-06 27.3 3.9 5.8e-05 22.8 2.0 2.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EMR62524.1 - 2.1e-05 24.4 0.1 3.6e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.12 EMR62524.1 - 0.0064 15.4 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_7 PF13241.1 EMR62524.1 - 0.04 14.1 0.0 0.092 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding IlvN PF07991.7 EMR62524.1 - 0.053 12.9 0.3 0.12 11.7 0.2 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 EMR62524.1 - 0.069 13.2 1.5 0.12 12.4 0.4 2.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3447 PF11929.3 EMR62526.1 - 0.017 14.8 0.2 11 5.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) IL7 PF01415.11 EMR62526.1 - 0.021 14.5 3.0 0.56 9.8 0.0 2.3 1 1 1 2 2 2 0 Interleukin 7/9 family COX2 PF00116.15 EMR62526.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, periplasmic domain Citrate_synt PF00285.16 EMR62527.1 - 2e-116 388.6 0.0 2.6e-116 388.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Beta-lactamase PF00144.19 EMR62528.1 - 1.3e-35 122.9 0.0 1.7e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase BUD22 PF09073.5 EMR62530.1 - 2.8e-71 240.8 52.9 1.2e-70 238.7 36.7 2.0 1 1 0 1 1 1 1 BUD22 Amidoligase_2 PF12224.3 EMR62531.1 - 1.1e-17 64.5 0.0 2.3e-15 56.9 0.0 2.2 2 0 0 2 2 2 2 Putative amidoligase enzyme SKG6 PF08693.5 EMR62532.1 - 0.001 18.3 0.2 0.001 18.3 0.1 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Lsm_interact PF05391.6 EMR62532.1 - 0.0041 16.4 0.8 0.0092 15.3 0.6 1.6 1 0 0 1 1 1 1 Lsm interaction motif Syndecan PF01034.15 EMR62532.1 - 0.0044 16.6 0.2 0.011 15.3 0.1 1.7 1 0 0 1 1 1 1 Syndecan domain Amnionless PF14828.1 EMR62532.1 - 0.0089 14.5 0.0 0.015 13.8 0.0 1.3 1 0 0 1 1 1 1 Amnionless VSP PF03302.8 EMR62532.1 - 0.019 13.6 0.3 0.025 13.2 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Podoplanin PF05808.6 EMR62532.1 - 0.035 13.6 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Podoplanin Mid2 PF04478.7 EMR62532.1 - 0.042 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.1 EMR62532.1 - 0.049 14.0 0.3 0.32 11.4 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.1 EMR62532.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Herpes_gE PF02480.11 EMR62532.1 - 0.084 11.1 0.0 0.12 10.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 EMR62532.1 - 0.13 11.8 0.2 0.13 11.8 0.1 2.4 3 0 0 3 3 2 0 Adenovirus E3 region protein CR2 BTB PF00651.26 EMR62533.1 - 7.2e-15 54.9 0.0 3.6e-09 36.5 0.0 2.7 2 1 0 2 2 2 2 BTB/POZ domain adh_short PF00106.20 EMR62534.1 - 4e-17 62.6 4.4 7.4e-16 58.5 3.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR62534.1 - 1.2e-08 34.9 0.1 1.5e-07 31.4 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR62534.1 - 7.9e-07 28.9 0.8 1.1e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EMR62534.1 - 0.0023 18.0 0.2 0.0046 17.0 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Orbi_VP6 PF01516.11 EMR62535.1 - 3.9 6.4 20.5 4.6 6.1 14.2 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 MOZ_SAS PF01853.13 EMR62536.1 - 3.1e-79 264.6 0.0 4.3e-79 264.1 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 EMR62536.1 - 0.032 13.9 6.8 0.018 14.7 2.2 2.2 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.17 EMR62536.1 - 0.092 12.4 1.1 0.23 11.2 0.8 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MIF4G PF02854.14 EMR62538.1 - 7.2e-52 175.8 0.0 1.5e-51 174.8 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EMR62538.1 - 5.2e-20 71.1 0.0 5.2e-20 71.1 0.0 2.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 Eno-Rase_FAD_bd PF07055.7 EMR62538.1 - 0.013 15.4 0.0 0.053 13.4 0.0 2.0 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain DUF1770 PF08589.5 EMR62539.1 - 1.3e-29 102.7 2.2 1.8e-29 102.2 1.5 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) E1_dh PF00676.15 EMR62540.1 - 2.3e-112 374.5 0.1 2.9e-112 374.2 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EMR62540.1 - 0.0026 16.7 0.0 0.0045 15.9 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DNA_pol_B PF00136.16 EMR62541.1 - 5.1e-111 371.7 1.1 7.7e-111 371.1 0.7 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EMR62541.1 - 2.2e-61 206.5 0.0 4e-61 205.6 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EMR62541.1 - 2.2e-37 128.6 0.0 4e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EMR62541.1 - 3.7e-24 84.3 10.0 3.7e-24 84.3 6.9 2.7 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal WHIM1 PF15612.1 EMR62542.1 - 0.0041 16.9 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 IFT57 PF10498.4 EMR62542.1 - 6.2 5.4 8.8 13 4.4 6.1 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 NOA36 PF06524.7 EMR62542.1 - 9.1 5.4 13.0 21 4.2 9.0 1.5 1 0 0 1 1 1 0 NOA36 protein PDT PF00800.13 EMR62543.1 - 1.1e-59 201.0 0.0 2e-59 200.2 0.0 1.4 1 1 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EMR62543.1 - 0.0007 19.0 0.0 0.0036 16.7 0.0 2.2 2 0 0 2 2 2 1 ACT domain Pex14_N PF04695.8 EMR62543.1 - 0.039 14.0 2.8 0.85 9.6 0.0 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PPR_2 PF13041.1 EMR62544.1 - 6.6e-23 80.4 0.3 7.3e-12 45.0 0.0 4.4 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.1 EMR62544.1 - 3.9e-13 48.5 3.3 0.049 13.9 0.0 7.3 9 0 0 9 9 9 3 Pentatricopeptide repeat domain PPR PF01535.15 EMR62544.1 - 2.1e-06 27.2 5.5 0.032 14.2 0.0 5.5 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.2 EMR62544.1 - 0.00049 19.5 2.1 4.6 6.8 0.3 4.7 5 0 0 5 5 5 2 PPR repeat MNE1 PF13762.1 EMR62544.1 - 0.0007 19.6 0.0 0.45 10.5 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial splicing apparatus component ATP13 PF12921.2 EMR62544.1 - 0.086 12.1 0.0 1.2 8.5 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial ATPase expression TPR_6 PF13174.1 EMR62544.1 - 0.84 10.2 5.7 40 4.9 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat eRF1_2 PF03464.10 EMR62545.1 - 6.4e-47 159.2 0.1 1.3e-46 158.1 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EMR62545.1 - 1.1e-39 135.2 0.5 2.3e-39 134.1 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EMR62545.1 - 2.4e-28 98.3 0.0 4.6e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 EMR62545.1 - 0.062 12.8 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Velvet PF11754.3 EMR62546.1 - 5.5e-39 133.8 0.0 8.6e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 Velvet factor PBP1_TM PF14812.1 EMR62546.1 - 0.24 11.7 2.8 0.44 10.8 2.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPT PF03151.11 EMR62547.1 - 5.6e-20 71.5 10.7 5.6e-20 71.5 7.5 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EMR62547.1 - 3.1e-09 36.1 15.5 5.6e-09 35.3 10.7 1.3 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EMR62547.1 - 0.0049 15.9 5.7 0.4 9.7 1.2 2.7 1 1 1 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 EMR62547.1 - 0.012 15.6 1.0 0.012 15.6 0.7 3.2 2 1 1 3 3 3 0 EamA-like transporter family DUF2614 PF11023.3 EMR62547.1 - 0.55 10.0 4.2 8.8 6.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) UDPG_MGDP_dh_N PF03721.9 EMR62549.1 - 8e-54 181.8 0.0 1.3e-53 181.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EMR62549.1 - 7.8e-31 106.1 0.0 1.6e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EMR62549.1 - 5.4e-30 103.6 0.0 1e-24 86.7 0.0 3.3 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 EMR62549.1 - 0.036 13.7 0.1 0.34 10.6 0.1 2.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldh_1_N PF00056.18 EMR62549.1 - 0.045 13.5 0.1 12 5.6 0.0 3.3 2 1 1 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EMR62549.1 - 0.053 12.4 0.0 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Methyltransf_2 PF00891.13 EMR62549.1 - 0.1 11.7 0.0 0.24 10.5 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase 14-3-3 PF00244.15 EMR62549.1 - 0.15 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 14-3-3 protein DASH_Spc34 PF08657.5 EMR62550.1 - 2.6e-55 187.9 1.8 1.1e-54 185.8 1.3 1.7 1 1 0 1 1 1 1 DASH complex subunit Spc34 IER PF05760.7 EMR62550.1 - 0.054 13.4 1.2 0.071 13.0 0.8 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) DASH_Spc19 PF08287.6 EMR62550.1 - 0.19 11.3 2.7 0.3 10.7 1.9 1.3 1 0 0 1 1 1 0 Spc19 IncA PF04156.9 EMR62550.1 - 0.32 10.5 3.4 0.46 10.0 2.4 1.2 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EMR62550.1 - 0.87 7.3 2.8 1.1 6.9 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3176 PF11374.3 EMR62551.1 - 3.6e-25 87.9 0.5 8.2e-25 86.8 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Glyco_hydro_cc PF11790.3 EMR62552.1 - 1.3e-21 77.1 0.0 1.7e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core NOA36 PF06524.7 EMR62552.1 - 3 7.0 6.7 3.7 6.7 4.7 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 EMR62552.1 - 4.1 6.0 12.7 5.5 5.6 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) OPT PF03169.10 EMR62553.1 - 1.3e-107 360.7 30.7 1.4e-88 297.9 15.1 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Hce2 PF14856.1 EMR62554.1 - 1.1e-16 60.4 0.1 1.3e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor adh_short PF00106.20 EMR62555.1 - 1.4e-18 67.4 0.2 2.2e-18 66.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR62555.1 - 6.4e-08 32.4 0.2 1.4e-07 31.3 0.0 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMR62555.1 - 0.00038 20.3 0.0 0.00052 19.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase LcrG PF07216.7 EMR62556.1 - 0.053 13.5 0.2 0.16 11.9 0.1 1.9 1 0 0 1 1 1 0 LcrG protein BBE PF08031.7 EMR62557.1 - 2.9e-05 23.8 0.0 5.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EMR62557.1 - 0.00012 21.5 3.3 0.0002 20.8 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 EMR62557.1 - 0.0086 15.4 0.2 0.3 10.3 0.1 2.4 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain Glyco_transf_22 PF03901.12 EMR62559.1 - 0.0019 17.2 1.6 0.0029 16.6 1.1 1.3 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PrsW-protease PF13367.1 EMR62559.1 - 0.011 14.9 0.5 0.011 14.9 0.4 1.5 2 0 0 2 2 2 0 Protease prsW family Polysacc_synt PF01943.12 EMR62559.1 - 0.032 13.4 3.1 0.051 12.8 2.2 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NrfD PF03916.9 EMR62559.1 - 0.056 12.8 6.9 0.049 13.0 3.9 1.4 1 1 0 1 1 1 0 Polysulphide reductase, NrfD DUF4013 PF13197.1 EMR62559.1 - 0.077 12.3 8.1 0.022 14.0 3.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4013) MerC PF03203.9 EMR62559.1 - 5.1 7.4 13.1 29 5.0 6.9 2.6 2 1 0 2 2 2 0 MerC mercury resistance protein Glyco_hydro_43 PF04616.9 EMR62561.1 - 2.9e-14 52.8 0.4 4.5e-14 52.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EMR62561.1 - 0.035 13.4 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain SET PF00856.23 EMR62562.1 - 4.3e-11 43.3 0.0 1.6e-09 38.2 0.0 2.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EMR62562.1 - 6.4e-08 32.3 9.5 6.4e-08 32.3 6.6 2.6 2 0 0 2 2 2 1 MYND finger CpXC PF14353.1 EMR62562.1 - 0.93 9.4 8.9 0.045 13.7 0.7 2.5 2 0 0 2 2 2 0 CpXC protein Fer4_21 PF14697.1 EMR62562.1 - 4.8 7.1 9.7 0.91 9.4 3.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain RasGAP PF00616.14 EMR62563.1 - 6.7e-44 149.9 0.1 4e-43 147.3 0.0 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EMR62563.1 - 2.5e-29 101.7 6.5 2.5e-29 101.7 4.5 2.1 2 0 0 2 2 2 1 RasGAP C-terminus MeMO_Hyd_G PF02964.11 EMR62563.1 - 0.043 13.7 0.2 0.12 12.2 0.2 1.7 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain DUF972 PF06156.8 EMR62563.1 - 4.2 7.7 13.6 10 6.5 0.7 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Pectinesterase PF01095.14 EMR62564.1 - 6.6e-13 47.8 0.0 9.3e-13 47.3 0.0 1.1 1 0 0 1 1 1 1 Pectinesterase BBE PF08031.7 EMR62565.1 - 0.15 11.9 0.0 0.39 10.6 0.0 1.7 2 0 0 2 2 2 0 Berberine and berberine like DSBA PF01323.15 EMR62567.1 - 1.7e-39 135.3 0.0 2e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EMR62567.1 - 0.00016 21.6 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 EMR62567.1 - 0.021 14.6 0.0 0.84 9.4 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain PTR2 PF00854.16 EMR62568.1 - 4.4e-23 81.6 0.2 6e-23 81.2 0.1 1.1 1 0 0 1 1 1 1 POT family PUCC PF03209.10 EMR62568.1 - 0.034 12.8 0.6 0.052 12.2 0.4 1.2 1 0 0 1 1 1 0 PUCC protein MFS_1 PF07690.11 EMR62568.1 - 0.61 8.7 13.1 0.016 13.9 4.1 2.0 2 1 0 2 2 2 0 Major Facilitator Superfamily HET PF06985.6 EMR62569.1 - 9.3e-17 61.4 0.0 1.5e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) His_Phos_1 PF00300.17 EMR62570.1 - 2.3e-15 57.0 0.0 4.3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NTF2 PF02136.15 EMR62571.1 - 6.3e-31 107.2 0.2 7e-31 107.0 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Amidoligase_2 PF12224.3 EMR62572.1 - 4e-17 62.6 0.0 6.2e-14 52.2 0.0 2.1 2 0 0 2 2 2 2 Putative amidoligase enzyme WD40 PF00400.27 EMR62573.1 - 8.6e-25 85.6 6.0 2.5e-10 39.8 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EMR62573.1 - 2.8e-17 62.3 0.0 7.2e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex IU_nuc_hydro PF01156.14 EMR62574.1 - 9.3e-24 84.2 0.0 1.1e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase COesterase PF00135.23 EMR62575.1 - 7.1e-87 292.3 0.1 9.1e-87 291.9 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR62575.1 - 1.3e-05 24.8 2.5 0.00015 21.4 0.6 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR62575.1 - 0.016 14.9 0.5 0.031 14.0 0.1 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Helicase_C PF00271.26 EMR62576.1 - 5.8e-11 42.1 0.0 1.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EMR62576.1 - 3e-05 23.6 10.8 6.2e-05 22.6 7.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMR62576.1 - 5.4e-05 22.7 11.8 0.00014 21.4 8.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMR62576.1 - 0.00015 21.4 8.4 0.00023 20.9 5.3 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMR62576.1 - 0.00025 21.0 10.0 0.00025 21.0 6.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EMR62576.1 - 0.00048 19.6 8.1 0.0014 18.1 5.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EMR62576.1 - 0.001 18.7 5.8 0.0025 17.4 4.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-H2C2_2 PF13465.1 EMR62576.1 - 0.25 11.6 0.0 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-C3HC4_4 PF15227.1 EMR62576.1 - 0.83 9.5 11.2 4.5 7.2 7.8 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EMR62576.1 - 1.5 8.3 8.2 4.5 6.8 5.7 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Bradykinin PF06753.7 EMR62577.1 - 0.042 13.3 0.1 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 Bradykinin FA_desaturase PF00487.19 EMR62578.1 - 2.3e-24 86.2 27.8 3.6e-24 85.5 19.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EMR62578.1 - 4.7e-08 33.1 0.0 9e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) zf-C3HC4_2 PF13923.1 EMR62579.1 - 0.0044 17.0 2.7 0.006 16.5 0.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR62579.1 - 0.0074 15.9 6.6 0.034 13.8 4.6 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMR62579.1 - 0.012 15.3 0.1 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMR62579.1 - 0.025 14.4 0.5 0.19 11.6 0.1 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Ima1_N PF09779.4 EMR62579.1 - 0.064 13.7 0.0 0.096 13.1 0.0 1.2 1 0 0 1 1 1 0 Ima1 N-terminal domain zf-C3HC4 PF00097.20 EMR62579.1 - 0.11 12.2 5.3 0.38 10.4 3.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMR62579.1 - 0.13 12.1 2.8 0.27 11.0 0.7 2.1 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.1 EMR62579.1 - 0.13 11.8 0.5 0.13 11.8 0.4 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FYVE PF01363.16 EMR62579.1 - 0.21 11.4 4.1 0.8 9.6 2.8 2.0 1 1 0 1 1 1 0 FYVE zinc finger zinc-ribbons_6 PF07191.7 EMR62579.1 - 0.91 9.3 5.0 0.34 10.7 1.3 1.8 2 1 0 2 2 2 0 zinc-ribbons CrtC PF07143.6 EMR62580.1 - 1.5e-14 53.9 2.4 9.1e-14 51.4 1.7 1.9 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) MarB PF13999.1 EMR62580.1 - 0.074 12.6 0.5 0.14 11.7 0.4 1.4 1 0 0 1 1 1 0 MarB protein SNF2_N PF00176.18 EMR62581.1 - 8.5e-19 67.4 0.0 1.3e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EMR62581.1 - 3.7e-05 23.6 0.0 0.00019 21.3 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMR62581.1 - 0.024 14.1 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF3337 PF11816.3 EMR62581.1 - 0.49 9.7 8.1 0.63 9.3 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) EthD PF07110.6 EMR62582.1 - 1.4e-06 29.1 0.0 1.8e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 EthD domain Cpn60_TCP1 PF00118.19 EMR62583.1 - 5.1e-142 473.9 2.1 6e-142 473.6 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MFS_1 PF07690.11 EMR62584.1 - 5e-34 117.5 23.1 7.1e-34 117.0 16.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FtsX PF02687.16 EMR62584.1 - 2.4 7.9 0.0 2.4 7.9 0.0 4.0 3 1 2 5 5 5 0 FtsX-like permease family TFIID_20kDa PF03847.8 EMR62585.1 - 3.8e-16 59.1 0.0 8.7e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EMR62585.1 - 0.0015 18.5 0.2 0.023 14.7 0.0 2.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMR62585.1 - 0.046 13.8 3.2 0.066 13.3 0.3 2.4 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 US2 PF02476.10 EMR62585.1 - 0.58 10.6 4.3 0.22 11.9 0.8 2.0 2 0 0 2 2 2 0 US2 family MFS_1 PF07690.11 EMR62586.1 - 4.2e-33 114.5 27.3 7.3e-33 113.7 16.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MOZ_SAS PF01853.13 EMR62587.1 - 4.7e-48 162.9 0.0 1.1e-30 106.2 0.0 2.9 3 0 0 3 3 3 2 MOZ/SAS family DUF2360 PF10152.4 EMR62587.1 - 0.13 12.5 3.3 5.1 7.3 0.1 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) MSA-2c PF12238.3 EMR62587.1 - 0.76 9.4 4.3 0.53 9.9 0.1 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c Abhydrolase_6 PF12697.2 EMR62588.1 - 1.1e-21 77.7 0.1 4.2e-21 75.8 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR62588.1 - 9e-16 58.1 0.2 7.2e-14 51.8 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR62588.1 - 0.00011 21.9 0.1 0.0018 18.0 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family MutS_V PF00488.16 EMR62591.1 - 2.8e-95 318.2 0.0 4.1e-95 317.6 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMR62591.1 - 5.8e-39 133.9 0.5 1.4e-38 132.7 0.4 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EMR62591.1 - 6.8e-25 87.7 0.7 2.1e-23 82.8 0.1 2.9 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.15 EMR62591.1 - 4.4e-17 62.1 0.0 2.2e-16 59.9 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EMR62591.1 - 2.3e-16 59.7 1.8 2.3e-16 59.7 1.3 2.7 3 0 0 3 3 3 1 MutS family domain IV Peptidase_M16 PF00675.15 EMR62591.1 - 0.078 12.7 0.2 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Serglycin PF04360.7 EMR62591.1 - 0.093 12.4 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Serglycin SCAN PF02023.12 EMR62591.1 - 0.13 11.7 1.3 0.37 10.2 0.9 1.8 1 0 0 1 1 1 0 SCAN domain AAA_23 PF13476.1 EMR62591.1 - 2.1 8.6 8.8 36 4.5 0.0 3.3 2 1 0 2 2 2 0 AAA domain Methyltransf_2 PF00891.13 EMR62592.1 - 1.7e-35 122.3 0.0 2.6e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EMR62592.1 - 0.0025 18.3 0.0 0.013 16.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR62592.1 - 0.012 16.0 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain HTH_24 PF13412.1 EMR62592.1 - 0.019 14.3 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.7 EMR62592.1 - 0.034 13.6 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EMR62592.1 - 0.043 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Sigma70_r3 PF04539.11 EMR62592.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 GMC_oxred_C PF05199.8 EMR62593.1 - 7.5e-16 58.7 0.0 1.1e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Choline_kinase PF01633.15 EMR62594.1 - 0.0011 18.6 0.0 0.036 13.6 0.0 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase tRNA_m1G_MT PF01746.16 EMR62595.1 - 1.1e-35 122.9 0.0 1.6e-23 83.2 0.0 2.5 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Auxin_canalis PF05703.6 EMR62595.1 - 0.0018 18.1 1.8 0.0037 17.1 1.2 1.5 1 0 0 1 1 1 1 Auxin canalisation Peptidase_S30 PF01577.11 EMR62595.1 - 0.12 11.7 6.1 0.26 10.6 4.2 1.5 1 0 0 1 1 1 0 Potyvirus P1 protease ATP-synt_C PF00137.16 EMR62596.1 - 2.7e-16 59.2 10.5 4.9e-16 58.3 7.3 1.5 1 0 0 1 1 1 1 ATP synthase subunit C MFS_3 PF05977.8 EMR62596.1 - 0.063 11.3 8.3 1.2 7.1 2.7 2.0 1 1 1 2 2 2 0 Transmembrane secretion effector PSD5 PF07637.6 EMR62596.1 - 0.085 12.9 0.1 0.85 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) F-box-like PF12937.2 EMR62597.1 - 0.00022 20.9 0.8 0.00075 19.1 0.1 2.3 2 0 0 2 2 2 1 F-box-like Rpn3_C PF08375.6 EMR62599.1 - 6.2e-25 87.3 2.2 1.8e-24 85.9 1.5 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EMR62599.1 - 3.6e-21 75.4 0.9 2.5e-20 72.7 0.0 2.7 4 0 0 4 4 4 1 PCI domain TPR_2 PF07719.12 EMR62599.1 - 0.025 14.4 0.1 0.092 12.7 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat ADH_zinc_N_2 PF13602.1 EMR62600.1 - 1.3e-18 68.1 0.7 2.1e-18 67.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMR62600.1 - 1.9e-14 53.3 0.1 3.6e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR62600.1 - 6.8e-05 22.5 0.0 0.0012 18.6 0.0 2.5 2 2 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ras PF00071.17 EMR62601.1 - 1.3e-58 196.9 0.3 1.5e-58 196.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR62601.1 - 3.6e-19 69.4 0.1 6.1e-19 68.6 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMR62601.1 - 1.4e-15 56.9 0.1 1.7e-15 56.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMR62601.1 - 2.3e-08 33.4 0.0 2.7e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMR62601.1 - 4.1e-08 32.8 0.0 5.9e-08 32.3 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMR62601.1 - 1.1e-05 25.3 0.0 1.5e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMR62601.1 - 0.029 14.4 0.1 2.4 8.2 0.0 2.5 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 EMR62601.1 - 0.038 13.1 0.3 0.16 11.1 0.0 2.0 2 1 0 3 3 3 0 Protein of unknown function, DUF258 G-alpha PF00503.15 EMR62601.1 - 0.15 10.7 0.4 10 4.7 0.0 2.3 1 1 1 2 2 2 0 G-protein alpha subunit KR PF08659.5 EMR62602.1 - 6.5e-23 81.3 0.1 1.2e-20 73.9 0.0 2.7 3 0 0 3 3 3 2 KR domain adh_short PF00106.20 EMR62602.1 - 1.9e-17 63.6 0.4 3.1e-16 59.7 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EMR62602.1 - 2.3e-16 59.4 1.3 5e-16 58.4 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR62602.1 - 3.8e-05 23.4 0.0 9.2e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMR62602.1 - 0.00032 21.5 0.1 0.0013 19.6 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cupin_2 PF07883.6 EMR62603.1 - 5.2e-11 41.8 1.3 1.3e-05 24.6 0.1 2.9 2 1 1 3 3 3 2 Cupin domain Cupin_1 PF00190.17 EMR62603.1 - 8.4e-07 28.5 0.1 1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EMR62603.1 - 0.00018 20.7 0.1 0.00056 19.2 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF861) 3-HAO PF06052.7 EMR62603.1 - 0.00076 18.9 0.6 0.0078 15.6 0.4 2.0 1 1 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Pirin PF02678.11 EMR62603.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 Pirin Peptidase_S8 PF00082.17 EMR62606.1 - 9.4e-54 182.4 1.3 1.6e-53 181.6 0.7 1.6 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.15 EMR62606.1 - 3.8e-28 97.0 2.7 4.7e-28 96.7 1.1 1.8 2 0 0 2 2 2 1 Proprotein convertase P-domain Metaviral_G PF09595.5 EMR62606.1 - 0.086 12.4 18.1 0.15 11.7 12.6 1.3 1 0 0 1 1 1 0 Metaviral_G glycoprotein Pectate_lyase_3 PF12708.2 EMR62607.1 - 2.8e-10 40.6 7.4 1.1e-09 38.7 0.2 2.2 2 0 0 2 2 2 2 Pectate lyase superfamily protein DUF2561 PF10812.3 EMR62608.1 - 0.096 12.2 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) MFS_1 PF07690.11 EMR62609.1 - 8.6e-37 126.6 29.0 8.6e-37 126.6 20.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily HSP20 PF00011.16 EMR62610.1 - 3.6e-18 65.3 0.4 8.4e-14 51.2 0.0 2.5 2 1 0 2 2 2 2 Hsp20/alpha crystallin family AATase PF07247.7 EMR62612.1 - 9.4e-08 31.0 0.0 1.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EMR62612.1 - 0.00066 18.6 0.3 0.0021 16.9 0.0 1.9 2 0 0 2 2 2 1 Condensation domain DUF336 PF03928.9 EMR62612.1 - 0.078 12.7 0.5 0.14 11.9 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF336) DUF2668 PF10873.3 EMR62612.1 - 0.094 12.8 0.2 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) BNR_2 PF13088.1 EMR62613.1 - 1e-06 28.3 0.0 0.0013 18.1 0.0 2.6 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EMR62613.1 - 0.00014 21.1 4.7 0.27 11.1 0.1 3.7 3 0 0 3 3 3 2 BNR/Asp-box repeat Glyco_hydro_62 PF03664.8 EMR62613.1 - 0.034 13.2 0.1 0.059 12.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 62 Sugar_tr PF00083.19 EMR62614.1 - 2.6e-80 270.2 27.8 3e-80 269.9 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR62614.1 - 3.4e-14 52.3 33.4 2.7e-12 46.0 20.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4408 PF14364.1 EMR62615.1 - 0.31 10.6 2.4 0.65 9.5 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) DUF3328 PF11807.3 EMR62616.1 - 1.2e-28 100.3 0.1 1.6e-28 99.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FAD_binding_4 PF01565.18 EMR62617.1 - 3.1e-24 85.0 1.7 5.7e-24 84.1 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR62617.1 - 0.00094 19.0 0.1 0.0022 17.8 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like ABC_tran PF00005.22 EMR62618.1 - 1.1e-35 122.9 0.2 5.8e-28 97.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMR62618.1 - 7.7e-12 45.1 21.7 9.7e-12 44.8 4.5 3.1 2 1 0 2 2 2 1 ABC transporter transmembrane region AAA_22 PF13401.1 EMR62618.1 - 2.4e-08 34.1 0.4 0.0014 18.8 0.0 3.2 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 EMR62618.1 - 3.6e-08 32.9 3.7 0.02 14.0 0.1 3.2 2 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMR62618.1 - 7.9e-08 32.6 0.1 0.18 11.7 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_25 PF13481.1 EMR62618.1 - 1.2e-07 31.3 0.1 0.0016 17.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.13 EMR62618.1 - 2.8e-07 30.2 0.1 0.0031 17.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 EMR62618.1 - 5.3e-07 28.8 0.3 0.016 14.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MobB PF03205.9 EMR62618.1 - 6.1e-07 29.2 0.4 0.023 14.3 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EMR62618.1 - 1e-06 28.1 0.2 0.0087 15.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EMR62618.1 - 1.8e-06 28.7 0.1 0.072 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EMR62618.1 - 2.8e-06 27.8 0.1 0.011 16.2 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF87 PF01935.12 EMR62618.1 - 4.2e-06 26.7 1.1 0.0061 16.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 EMR62618.1 - 4.6e-06 27.0 0.2 0.074 13.3 0.1 2.3 2 0 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.4 EMR62618.1 - 1e-05 24.3 2.2 0.022 13.3 0.0 2.6 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.1 EMR62618.1 - 1.9e-05 24.7 0.2 0.43 10.5 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EMR62618.1 - 3.1e-05 23.2 0.5 0.094 11.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EMR62618.1 - 4.1e-05 23.8 0.0 0.062 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMR62618.1 - 9.9e-05 22.2 0.0 0.58 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Pox_A32 PF04665.7 EMR62618.1 - 0.0001 21.6 0.1 0.37 10.0 0.0 2.3 2 0 0 2 2 2 2 Poxvirus A32 protein cobW PF02492.14 EMR62618.1 - 0.00012 21.5 0.8 0.15 11.4 0.2 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EMR62618.1 - 0.00021 20.8 2.5 0.17 11.2 0.2 2.5 2 1 0 2 2 2 2 AAA-like domain NTPase_1 PF03266.10 EMR62618.1 - 0.00021 21.0 0.7 0.15 11.7 0.0 3.2 3 0 0 3 3 3 1 NTPase Arch_ATPase PF01637.13 EMR62618.1 - 0.00025 20.8 0.1 0.18 11.4 0.0 2.6 2 1 0 2 2 2 1 Archaeal ATPase ATP_bind_1 PF03029.12 EMR62618.1 - 0.001 18.6 0.3 0.98 8.9 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EMR62618.1 - 0.0012 18.7 1.0 1.8 8.5 0.1 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.7 EMR62618.1 - 0.0014 18.3 0.7 2 8.0 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.1 EMR62618.1 - 0.0017 18.2 0.0 6.8 6.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EMR62618.1 - 0.002 18.2 0.2 1.6 8.9 0.0 2.9 3 0 0 3 3 2 1 RNA helicase UPF0079 PF02367.12 EMR62618.1 - 0.0029 17.2 0.2 0.97 9.0 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 EMR62618.1 - 0.0031 17.0 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 EMR62618.1 - 0.0059 16.3 0.5 1.2 8.8 0.1 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EMR62618.1 - 0.0098 15.6 0.2 1.5 8.6 0.1 2.9 2 0 0 2 2 2 1 Part of AAA domain Dynamin_N PF00350.18 EMR62618.1 - 0.01 15.6 0.3 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family PPV_E1_C PF00519.12 EMR62618.1 - 0.013 14.1 0.1 0.18 10.4 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase DEAD PF00270.24 EMR62618.1 - 0.016 14.7 0.6 2.1 7.7 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.13 EMR62618.1 - 0.02 14.4 0.2 5.9 6.3 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EMR62618.1 - 0.021 15.0 0.5 1.4 9.1 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 EMR62618.1 - 0.027 13.5 0.0 3.5 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Adeno_IVa2 PF02456.10 EMR62618.1 - 0.032 12.8 0.4 4.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_11 PF13086.1 EMR62618.1 - 0.045 13.3 0.0 4.4 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EMR62618.1 - 0.062 12.8 0.2 13 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EMR62618.1 - 0.08 11.9 0.3 6.9 5.5 0.0 2.2 2 0 0 2 2 2 0 Septin Zot PF05707.7 EMR62618.1 - 0.091 12.2 0.1 11 5.4 0.0 2.6 3 0 0 3 3 2 0 Zonular occludens toxin (Zot) SRP54 PF00448.17 EMR62618.1 - 0.097 12.1 0.4 2.8 7.3 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 EMR62618.1 - 0.11 11.6 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.13 EMR62618.1 - 0.12 11.8 0.2 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_PrkA PF08298.6 EMR62618.1 - 0.13 10.9 0.0 0.98 8.0 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain IstB_IS21 PF01695.12 EMR62618.1 - 0.14 11.5 1.7 4.6 6.6 0.0 3.3 4 0 0 4 4 3 0 IstB-like ATP binding protein KaiC PF06745.8 EMR62618.1 - 1.6 7.7 8.1 1.9 7.5 0.0 3.5 4 0 0 4 4 4 0 KaiC HMG-CoA_red PF00368.13 EMR62619.1 - 1.1e-155 517.8 5.0 1.5e-155 517.5 3.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EMR62619.1 - 1.9e-43 147.8 1.4 3.2e-43 147.0 0.9 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EMR62619.1 - 5e-13 48.7 4.8 1.1e-10 41.1 3.4 2.5 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EMR62619.1 - 8.6e-08 30.5 2.0 8.6e-08 30.5 1.4 1.5 2 0 0 2 2 2 1 Patched family Mitofilin PF09731.4 EMR62620.1 - 2e-141 472.5 6.2 3.2e-141 471.8 4.3 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein ATP-synt_B PF00430.13 EMR62620.1 - 0.015 15.0 3.2 0.015 15.0 2.2 2.5 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) HMG_box_5 PF14887.1 EMR62621.1 - 0.067 12.9 0.6 0.095 12.5 0.4 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box 5 p450 PF00067.17 EMR62622.1 - 1.1e-45 156.0 1.6 1.2e-34 119.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Isochorismatase PF00857.15 EMR62624.1 - 1.1e-30 106.8 0.0 1.7e-30 106.2 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family Syja_N PF02383.13 EMR62625.1 - 5.1e-87 291.6 0.0 6.2e-87 291.3 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain FAD_binding_4 PF01565.18 EMR62626.1 - 4e-11 42.5 0.2 1.1e-10 41.1 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR62626.1 - 0.087 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like Abhydrolase_3 PF07859.8 EMR62627.1 - 1.6e-25 89.9 0.2 1.9e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EMR62627.1 - 2.7e-11 42.7 0.0 8e-11 41.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Glyco_hydro_31 PF01055.21 EMR62628.1 - 1.6e-130 435.8 0.9 2e-130 435.5 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMR62628.1 - 4.3e-05 23.2 0.4 0.00036 20.3 0.1 2.6 2 1 0 2 2 2 1 Galactose mutarotase-like adh_short PF00106.20 EMR62629.1 - 1e-16 61.3 0.4 1.8e-16 60.4 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR62629.1 - 1.2e-07 31.5 0.2 2e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 KR domain p450 PF00067.17 EMR62630.1 - 1.1e-32 113.2 0.0 1.6e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth PF01397.16 EMR62630.1 - 0.013 14.8 0.0 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain MR_MLE_C PF13378.1 EMR62631.1 - 1.9e-18 66.4 0.2 4.3e-18 65.3 0.2 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EMR62631.1 - 3.8e-11 43.3 0.2 2.1e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EMR62631.1 - 0.00031 20.7 0.2 0.0028 17.6 0.1 2.3 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain CFEM PF05730.6 EMR62632.1 - 1.6e-13 50.2 11.3 2.8e-13 49.4 7.8 1.4 1 0 0 1 1 1 1 CFEM domain DUF3852 PF12963.2 EMR62632.1 - 0.041 13.9 0.1 0.041 13.9 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3852) SKG6 PF08693.5 EMR62632.1 - 0.36 10.1 2.7 0.92 8.8 1.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain p450 PF00067.17 EMR62633.1 - 2e-68 231.0 0.0 2.6e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zip PF02535.17 EMR62634.1 - 1.1e-25 90.3 50.5 1.2e-12 47.5 5.6 4.0 2 1 3 5 5 5 3 ZIP Zinc transporter Tannase PF07519.6 EMR62635.1 - 2.5e-93 313.3 0.0 2.9e-93 313.1 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EMR62635.1 - 5.5e-05 23.1 0.2 0.0009 19.1 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR62635.1 - 0.00015 21.0 0.1 0.13 11.5 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMR62635.1 - 0.0018 18.0 0.1 0.45 10.2 0.1 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrophobin_2 PF06766.6 EMR62638.1 - 3.8e-30 103.3 9.6 5.3e-30 102.9 6.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin MFS_1 PF07690.11 EMR62640.1 - 3.1e-37 128.1 32.6 3.8e-37 127.8 21.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_U4 PF03419.8 EMR62640.1 - 0.065 12.3 3.9 0.13 11.3 2.7 1.4 1 0 0 1 1 1 0 Sporulation factor SpoIIGA JmjC PF02373.17 EMR62641.1 - 2.2e-10 40.7 0.2 7.6e-10 39.0 0.2 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EMR62641.1 - 0.012 15.1 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Glyco_hydro_43 PF04616.9 EMR62642.1 - 4.6e-28 98.1 2.3 6.2e-28 97.6 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GatB_Yqey PF02637.13 EMR62643.1 - 0.05 13.3 0.6 0.093 12.4 0.3 1.6 1 1 1 2 2 2 0 GatB domain DUF1996 PF09362.5 EMR62644.1 - 1.1e-87 293.5 0.8 1.5e-87 293.1 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Asp PF00026.18 EMR62646.1 - 1.1e-73 248.2 8.8 1.4e-73 247.9 6.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMR62646.1 - 3.3e-08 33.6 2.3 5.2e-08 33.0 0.3 2.2 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMR62646.1 - 0.00033 21.1 2.4 0.023 15.1 0.6 3.1 2 1 0 2 2 2 1 Aspartyl protease DEAD PF00270.24 EMR62647.1 - 2.4e-45 154.0 0.2 3.9e-44 150.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR62647.1 - 2.4e-20 72.1 0.1 6.7e-20 70.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EMR62647.1 - 0.0029 16.1 1.0 0.54 8.6 0.0 3.4 1 1 3 4 4 4 1 Protein of unknown function (DUF1253) ResIII PF04851.10 EMR62647.1 - 0.033 14.0 0.0 0.39 10.5 0.0 2.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit BCAS3 PF12490.3 EMR62647.1 - 0.085 12.1 0.3 0.19 10.9 0.2 1.5 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 DUF2183 PF09949.4 EMR62648.1 - 2.6e-33 113.9 0.0 5.8e-33 112.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 EMR62648.1 - 0.0064 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Dioxygenase_C PF00775.16 EMR62650.1 - 0.003 16.8 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Nucleos_tra2_C PF07662.8 EMR62651.1 - 1.6e-71 240.1 3.2 1.6e-71 240.1 2.2 2.4 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EMR62651.1 - 9.9e-20 70.6 4.5 9.9e-20 70.6 3.1 2.8 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus dCMP_cyt_deam_1 PF00383.17 EMR62652.1 - 7.1e-09 35.2 0.0 1.5e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EMR62652.1 - 0.018 14.9 1.2 0.061 13.1 0.9 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase Fungal_trans PF04082.13 EMR62653.1 - 2.8e-09 36.2 1.0 5e-09 35.4 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DIOX_N PF14226.1 EMR62654.1 - 1.9e-20 73.5 0.1 5.2e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMR62654.1 - 6.7e-17 61.6 0.0 1.4e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyoxalase PF00903.20 EMR62655.1 - 1.1e-12 48.0 0.1 2.3e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMR62655.1 - 7.3e-12 45.8 0.1 1.1e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EMR62655.1 - 4.6e-07 29.8 0.0 7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TauD PF02668.11 EMR62657.1 - 3.2e-36 125.3 0.1 5e-36 124.7 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_3 PF01494.14 EMR62658.1 - 1.4e-18 67.0 2.2 5.1e-18 65.2 1.5 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EMR62658.1 - 4.4e-05 23.2 0.9 0.0023 17.7 0.6 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EMR62658.1 - 0.00037 20.4 0.1 0.0012 18.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR62658.1 - 0.00052 19.0 1.0 0.0037 16.2 0.1 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMR62658.1 - 0.014 14.3 0.7 2.1 7.1 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.19 EMR62658.1 - 0.067 12.2 0.1 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase SE PF08491.5 EMR62658.1 - 0.1 11.4 0.0 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox PF00070.22 EMR62658.1 - 0.11 12.8 0.3 0.3 11.5 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EMR62659.1 - 1.6e-25 89.9 0.6 2.1e-25 89.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR62659.1 - 8.1e-18 65.0 0.0 1e-17 64.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR62659.1 - 3.7e-10 39.7 0.5 5.3e-10 39.2 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR62659.1 - 1.5e-09 38.1 0.4 2.2e-09 37.5 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR62659.1 - 0.00022 20.5 0.1 0.00031 20.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DUF1776 PF08643.5 EMR62659.1 - 0.0022 17.1 0.0 0.21 10.7 0.0 2.7 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EMR62659.1 - 0.037 13.8 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Brix PF04427.13 EMR62660.1 - 5.2e-56 189.3 0.0 7.1e-56 188.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain Macoilin PF09726.4 EMR62660.1 - 0.024 12.9 5.3 0.032 12.5 3.7 1.3 1 0 0 1 1 1 0 Transmembrane protein Transp_cyt_pur PF02133.10 EMR62661.1 - 8.3e-74 248.7 26.8 7e-49 166.5 6.2 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin p450 PF00067.17 EMR62662.1 - 6.1e-30 104.1 0.1 2.4e-28 98.8 0.1 2.1 1 1 0 1 1 1 1 Cytochrome P450 CIA30 PF08547.7 EMR62663.1 - 0.085 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) DEAD PF00270.24 EMR62664.1 - 1.3e-46 158.1 0.0 2.1e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR62664.1 - 5.7e-27 93.3 0.0 1.3e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR62664.1 - 0.00034 20.5 0.0 0.0011 18.8 0.0 1.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMR62664.1 - 0.043 12.6 0.0 0.11 11.2 0.0 1.6 2 0 0 2 2 2 0 SNF2 family N-terminal domain API5 PF05918.6 EMR62664.1 - 2.1 6.7 5.4 3.6 5.9 3.4 1.6 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) TauD PF02668.11 EMR62665.1 - 1.2e-32 113.5 0.1 2.4e-32 112.6 0.1 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RrnaAD PF00398.15 EMR62667.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FAD_binding_4 PF01565.18 EMR62667.1 - 0.16 11.4 1.1 0.29 10.5 0.5 1.7 2 0 0 2 2 2 0 FAD binding domain PLRV_ORF5 PF01690.12 EMR62667.1 - 0.22 10.6 21.9 0.32 10.0 15.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF1180 PF06679.7 EMR62667.1 - 0.22 11.3 1.4 0.5 10.2 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Lamp PF01299.12 EMR62667.1 - 1.2 8.1 7.2 1.9 7.5 5.0 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) GPP34 PF05719.6 EMR62669.1 - 6.7e-64 215.7 0.2 8.7e-64 215.3 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) HUN PF08729.5 EMR62670.1 - 1.6e-13 50.3 0.3 3.8e-13 49.0 0.2 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Glyco_hydro_61 PF03443.9 EMR62671.1 - 3e-32 112.2 0.0 1.4e-31 110.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 EMR62672.1 - 7.1e-44 149.9 38.8 1.9e-41 142.0 26.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR62672.1 - 2.6e-17 62.2 19.9 3.6e-17 61.7 13.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMR62672.1 - 1.4e-14 53.5 5.5 1.4e-14 53.5 3.8 3.4 3 1 1 4 4 4 2 Sugar (and other) transporter MFS_2 PF13347.1 EMR62672.1 - 2.2e-07 29.6 30.4 1.1e-05 24.0 5.8 3.4 3 1 0 3 3 3 2 MFS/sugar transport protein Glyco_hydro_45 PF02015.11 EMR62673.1 - 2.5e-89 298.6 18.3 2.9e-89 298.4 12.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 NIF3 PF01784.13 EMR62674.1 - 1.9e-46 158.6 0.0 9.3e-46 156.3 0.0 1.8 1 1 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) F-box PF00646.28 EMR62675.1 - 3e-07 29.9 0.7 6.1e-07 28.9 0.5 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMR62675.1 - 0.00024 20.7 0.6 0.00045 19.8 0.4 1.4 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EMR62675.1 - 0.2 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 PRANC domain p450 PF00067.17 EMR62676.1 - 1.1e-50 172.5 0.0 3.1e-50 171.0 0.0 1.5 1 1 1 2 2 2 1 Cytochrome P450 PHY PF00360.15 EMR62676.1 - 0.053 12.6 0.1 0.09 11.9 0.1 1.3 1 0 0 1 1 1 0 Phytochrome region XPC-binding PF09280.6 EMR62676.1 - 2.5 7.6 5.0 3.1 7.3 0.1 2.8 3 0 0 3 3 3 0 XPC-binding domain FMO-like PF00743.14 EMR62677.1 - 9.8e-28 96.6 0.0 1.4e-15 56.5 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMR62677.1 - 1.4e-19 70.9 0.1 1.6e-18 67.4 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR62677.1 - 2.8e-09 36.3 1.0 2.3e-07 30.0 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMR62677.1 - 1.8e-07 31.2 0.0 3.6e-05 23.7 0.1 3.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR62677.1 - 4.5e-07 29.7 0.8 1.3e-05 25.0 0.2 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EMR62677.1 - 0.00015 21.6 0.0 0.00069 19.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR62677.1 - 0.0059 15.5 2.2 1 8.1 0.1 2.6 2 1 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 EMR62677.1 - 0.019 14.0 0.4 0.084 11.9 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 EMR62677.1 - 0.12 12.5 0.2 1.6 8.8 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EMR62677.1 - 5.3 7.5 5.0 10 6.6 0.2 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase BolA PF01722.13 EMR62678.1 - 1.8e-20 72.6 0.0 2.2e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein adh_short PF00106.20 EMR62679.1 - 7.5e-18 64.9 0.3 1.4e-16 60.8 0.2 2.0 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR62679.1 - 2.2e-08 33.9 0.1 3.5e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR62679.1 - 0.00038 20.3 0.0 0.00056 19.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EMR62679.1 - 0.0029 16.5 0.0 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMR62679.1 - 0.043 13.8 0.0 0.15 12.0 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EMR62679.1 - 0.046 13.1 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Asparaginase PF00710.15 EMR62681.1 - 4.5e-39 134.1 0.0 5.7e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Asparaginase MFS_1 PF07690.11 EMR62683.1 - 5.3e-52 176.6 21.6 1.2e-47 162.3 6.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EMR62683.1 - 1.3e-05 24.1 0.1 1.3e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 BT1 family OATP PF03137.15 EMR62683.1 - 3.1e-05 22.2 0.1 0.059 11.4 1.5 2.2 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family PUCC PF03209.10 EMR62683.1 - 0.00031 19.5 0.3 0.00031 19.5 0.2 2.8 3 1 0 3 3 3 1 PUCC protein PGAMP PF07644.6 EMR62683.1 - 0.0018 17.9 0.4 0.0035 17.0 0.3 1.5 1 0 0 1 1 1 1 Planctomycete PGAMP Mem_trans PF03547.13 EMR62683.1 - 0.011 14.0 0.0 0.028 12.7 0.0 1.7 1 0 0 1 1 1 0 Membrane transport protein Folate_carrier PF01770.13 EMR62683.1 - 0.028 12.9 0.0 0.061 11.8 0.0 1.7 1 0 0 1 1 1 0 Reduced folate carrier Vps51 PF08700.6 EMR62684.1 - 1.2e-27 95.5 0.0 1.9e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 EMR62684.1 - 0.0022 16.5 0.2 0.0029 16.1 0.1 1.2 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 EMR62684.1 - 0.043 13.7 0.1 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 BBP1_C PF15272.1 EMR62684.1 - 0.12 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal CENP-F_N PF10481.4 EMR62684.1 - 0.25 10.6 0.1 0.25 10.6 0.1 1.7 2 0 0 2 2 2 0 Cenp-F N-terminal domain RPAP1_C PF08620.5 EMR62686.1 - 1e-27 95.7 0.0 1.9e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EMR62686.1 - 2e-17 62.5 1.7 3.6e-17 61.6 1.2 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal DIT1_PvcA PF05141.7 EMR62687.1 - 1.4e-76 257.4 0.0 1.1e-38 133.1 0.0 2.1 1 1 1 2 2 2 2 Pyoverdine/dityrosine biosynthesis protein PALP PF00291.20 EMR62688.1 - 1.7e-27 96.4 0.0 3.2e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 EMR62688.1 - 1.6e-08 34.9 0.0 4.9e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain NAD_synthase PF02540.12 EMR62689.1 - 1.8e-25 89.2 0.0 1.1e-24 86.6 0.0 2.0 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 EMR62689.1 - 3.1e-24 85.3 0.0 8.8e-24 83.8 0.0 1.8 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase NAD_binding_4 PF07993.7 EMR62690.1 - 1.5e-35 122.2 0.0 2.2e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EMR62690.1 - 1.2e-09 37.9 0.0 1.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMR62690.1 - 2.6e-05 24.4 0.1 7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.23 EMR62690.1 - 5.9e-05 21.6 0.0 0.0024 16.3 0.0 2.6 2 1 1 3 3 3 1 AMP-binding enzyme 3Beta_HSD PF01073.14 EMR62690.1 - 0.0031 16.2 0.0 0.0088 14.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMR62690.1 - 0.0046 15.8 0.0 0.0084 15.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EMR62690.1 - 0.035 14.0 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Saccharop_dh PF03435.13 EMR62690.1 - 0.043 12.7 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase MFS_1 PF07690.11 EMR62691.1 - 5.9e-19 67.9 30.2 8.4e-15 54.3 6.0 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily Cation_ATPase_C PF00689.16 EMR62691.1 - 1.2 8.6 7.5 2.3 7.6 0.0 3.7 2 1 2 4 4 4 0 Cation transporting ATPase, C-terminus DUF3353 PF11833.3 EMR62691.1 - 5.7 6.3 7.2 0.36 10.2 0.7 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) Polysacc_deac_1 PF01522.16 EMR62692.1 - 2.6e-28 98.1 0.0 3.5e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Abhydrolase_2 PF02230.11 EMR62693.1 - 5.9e-05 22.6 0.1 0.00017 21.1 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase RseA_C PF03873.8 EMR62693.1 - 1.7 8.6 6.2 0.26 11.2 1.2 1.9 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain FAD_binding_3 PF01494.14 EMR62695.1 - 7.3e-56 189.7 0.0 1e-55 189.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR62695.1 - 8.3e-13 47.9 0.2 1.1e-05 24.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR62695.1 - 6.5e-06 24.8 0.0 0.01 14.3 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 EMR62695.1 - 3.6e-05 24.0 0.0 0.046 14.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR62695.1 - 0.00035 19.7 0.0 0.00064 18.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EMR62695.1 - 0.0041 17.1 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR62695.1 - 0.0055 16.7 0.6 0.036 14.0 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Abhydrolase_1 PF00561.15 EMR62696.1 - 3.3e-18 66.1 0.1 1.7e-16 60.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EMR62696.1 - 4.4e-14 52.2 0.0 1.2e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_6 PF12697.2 EMR62696.1 - 1.4e-06 28.3 1.3 5.3e-06 26.4 0.9 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.2 EMR62697.1 - 2.6e-16 59.7 0.3 1.1e-12 48.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMR62697.1 - 1.5e-10 41.3 0.2 6.8e-08 32.8 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMR62697.1 - 1.6e-08 33.9 0.7 6e-06 25.8 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EMR62697.1 - 4.8e-07 29.3 0.2 0.00046 20.1 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 EMR62697.1 - 8.8e-06 25.8 0.6 0.00011 22.3 0.1 2.9 1 1 1 3 3 3 1 Ankyrin repeats (many copies) ADH_N PF08240.7 EMR62698.1 - 1.9e-27 95.1 4.2 4e-27 94.1 2.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR62698.1 - 2.1e-14 53.1 0.0 1.2e-13 50.7 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMR62698.1 - 0.001 18.2 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EMR62698.1 - 0.071 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Aminotran_3 PF00202.16 EMR62699.1 - 1e-41 142.9 0.0 1.6e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III DUF1767 PF08585.7 EMR62700.1 - 0.0005 20.2 0.0 0.0005 20.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1767) Menin PF05053.8 EMR62700.1 - 0.018 13.2 2.1 0.021 13.0 1.5 1.1 1 0 0 1 1 1 0 Menin Adaptin_N PF01602.15 EMR62701.1 - 1.8e-114 382.9 4.1 1.1e-101 340.8 1.2 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.2 EMR62701.1 - 4.9e-20 72.1 0.1 1.7e-19 70.3 0.0 1.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EMR62701.1 - 6.3e-14 52.0 0.1 6.5e-07 29.5 0.0 3.9 3 2 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EMR62701.1 - 2e-09 36.7 2.4 0.0089 16.0 0.0 5.0 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EMR62701.1 - 0.0019 18.6 0.0 11 6.6 0.0 4.7 5 0 0 5 5 5 1 HEAT-like repeat Arm PF00514.18 EMR62701.1 - 0.0048 16.6 0.5 25 4.8 0.0 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat UNC45-central PF11701.3 EMR62701.1 - 0.0084 15.7 0.1 0.74 9.4 0.1 2.7 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central Atx10homo_assoc PF09759.4 EMR62701.1 - 0.047 13.4 0.0 1 9.1 0.0 2.7 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 EMR62701.1 - 0.057 12.7 0.1 2.2 7.6 0.0 2.9 2 1 1 3 3 3 0 CLASP N terminal Bac_luciferase PF00296.15 EMR62703.1 - 6.8e-55 186.3 0.2 2.3e-54 184.6 0.1 1.7 1 1 1 2 2 2 1 Luciferase-like monooxygenase PAP2 PF01569.16 EMR62704.1 - 2.2e-21 75.8 1.9 2.2e-21 75.8 1.3 2.4 2 1 1 3 3 3 1 PAP2 superfamily DUF983 PF06170.7 EMR62704.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) MFS_1 PF07690.11 EMR62706.1 - 1.6e-20 73.1 42.4 1.6e-20 73.1 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Na_K-ATPase PF00287.13 EMR62706.1 - 0.26 10.0 1.1 5.8 5.5 0.2 2.1 2 0 0 2 2 2 0 Sodium / potassium ATPase beta chain MFS_1 PF07690.11 EMR62707.1 - 4.3e-19 68.4 18.1 5e-10 38.6 6.2 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 EMR62707.1 - 0.34 10.7 5.8 0.18 11.6 0.5 2.7 3 0 0 3 3 3 0 MFS_1 like family SRP54 PF00448.17 EMR62708.1 - 4.1e-77 258.0 1.7 6.8e-77 257.3 1.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EMR62708.1 - 1.8e-25 89.1 3.1 1.8e-25 89.1 2.1 4.3 4 1 1 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 EMR62708.1 - 2.2e-12 46.8 0.1 6.3e-12 45.4 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EMR62708.1 - 1.1e-08 34.7 0.1 2.6e-08 33.5 0.1 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EMR62708.1 - 8.3e-08 32.2 0.0 2.6e-07 30.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 EMR62708.1 - 1e-05 25.2 0.1 3.4e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EMR62708.1 - 1.6e-05 25.7 0.0 3.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EMR62708.1 - 0.00018 21.0 0.1 0.00052 19.4 0.1 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EMR62708.1 - 0.0012 18.8 0.0 0.36 10.7 0.0 2.7 2 1 0 3 3 3 1 AAA domain APS_kinase PF01583.15 EMR62708.1 - 0.0013 18.4 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 EMR62708.1 - 0.0016 17.6 0.0 0.0032 16.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin ATP_bind_1 PF03029.12 EMR62708.1 - 0.0016 18.0 0.1 0.041 13.4 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EMR62708.1 - 0.0021 18.2 0.0 0.0061 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR62708.1 - 0.0026 17.7 0.1 0.0065 16.4 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EMR62708.1 - 0.0028 17.9 0.0 0.0067 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EMR62708.1 - 0.0033 16.8 0.1 0.018 14.4 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase ArgK PF03308.11 EMR62708.1 - 0.0059 15.4 0.9 0.0059 15.4 0.6 2.3 2 1 0 2 2 2 1 ArgK protein AAA_10 PF12846.2 EMR62708.1 - 0.0093 15.4 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain SRPRB PF09439.5 EMR62708.1 - 0.0097 15.1 0.8 2.2 7.4 0.1 3.1 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit TrwB_AAD_bind PF10412.4 EMR62708.1 - 0.0099 14.5 0.0 0.021 13.4 0.0 1.5 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.1 EMR62708.1 - 0.025 14.5 0.3 0.057 13.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMR62708.1 - 0.035 13.8 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain 6PF2K PF01591.13 EMR62708.1 - 0.038 13.0 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Arf PF00025.16 EMR62708.1 - 0.069 12.3 0.0 0.25 10.5 0.0 1.9 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA PF00004.24 EMR62708.1 - 0.07 13.3 0.3 0.3 11.3 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 EMR62708.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Torsin Glyco_hydro_43 PF04616.9 EMR62709.1 - 2.2e-55 187.7 14.2 3.8e-49 167.3 1.5 2.5 2 1 1 3 3 3 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EMR62709.1 - 1.5e-09 37.7 1.6 0.00084 18.7 0.0 2.9 3 1 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain LysM PF01476.15 EMR62710.1 - 2.4e-11 43.3 0.0 0.00096 18.9 0.0 4.4 4 0 0 4 4 4 3 LysM domain NLPC_P60 PF00877.14 EMR62710.1 - 0.01 15.6 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 NlpC/P60 family UPF0203 PF05254.7 EMR62710.1 - 0.098 12.5 4.2 0.44 10.4 0.1 3.5 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0203) HET PF06985.6 EMR62711.1 - 4.2e-14 52.8 0.0 7.9e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pro_dh PF01619.13 EMR62713.1 - 1.8e-29 102.7 0.2 6.4e-29 100.9 0.1 1.7 1 1 0 1 1 1 1 Proline dehydrogenase Aa_trans PF01490.13 EMR62714.1 - 1.9e-14 52.9 19.9 1.6e-09 36.7 7.8 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EMR62714.1 - 1.7e-05 23.8 9.8 1.7e-05 23.8 6.8 2.2 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Aldedh PF00171.17 EMR62716.1 - 1.1e-88 297.6 0.0 1.3e-88 297.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SNF PF00209.13 EMR62717.1 - 4.7e-75 253.0 29.3 8.3e-74 248.9 20.3 2.2 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF3810 PF12725.2 EMR62717.1 - 0.1 11.4 0.6 0.19 10.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Dus PF01207.12 EMR62718.1 - 2.2e-54 184.3 0.0 5.3e-54 183.1 0.0 1.6 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) adh_short_C2 PF13561.1 EMR62720.1 - 4.6e-20 72.4 0.0 6e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR62720.1 - 1.1e-17 64.4 0.1 1.5e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Peptidase_C7 PF01830.13 EMR62720.1 - 0.065 12.3 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase C7 family GST_N_2 PF13409.1 EMR62721.1 - 3e-08 33.5 0.0 7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR62721.1 - 4.3e-07 29.8 0.0 9.1e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMR62721.1 - 5.2e-07 29.7 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR62721.1 - 7e-06 25.8 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NAS PF03059.11 EMR62722.1 - 2.7e-62 210.4 0.0 3.3e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.1 EMR62722.1 - 6.2e-06 25.8 0.0 1.2e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR62722.1 - 0.0085 16.6 0.0 0.014 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EMR62723.1 - 1.3e-28 99.8 0.0 2.6e-28 98.8 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase HTH_24 PF13412.1 EMR62723.1 - 0.053 12.9 0.0 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.15 EMR62723.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Put_DNA-bind_N PF06971.8 EMR62723.1 - 0.13 12.0 0.1 2.9 7.7 0.1 2.2 1 1 1 2 2 2 0 Putative DNA-binding protein N-terminus TP_methylase PF00590.15 EMR62724.1 - 6.9e-41 140.2 5.7 5.1e-40 137.4 2.2 2.7 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EMR62724.1 - 3.2e-13 49.8 0.1 6.1e-12 45.6 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EMR62724.1 - 3.6e-08 32.5 0.1 3.3e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EMR62724.1 - 1.1e-05 24.2 0.0 2.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central CW_binding_2 PF04122.7 EMR62724.1 - 0.034 14.3 0.1 15 5.8 0.0 3.0 3 0 0 3 3 3 0 Putative cell wall binding repeat 2 Abhydrolase_2 PF02230.11 EMR62725.1 - 4e-36 124.4 0.0 6e-29 101.0 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EMR62725.1 - 1.6e-07 31.4 0.5 2.9e-07 30.5 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR62725.1 - 2.9e-06 27.0 0.0 7.5e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR62725.1 - 2.7e-05 23.4 0.0 0.00012 21.4 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EMR62725.1 - 0.00015 21.3 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EMR62725.1 - 0.044 13.0 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Cutinase PF01083.17 EMR62725.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase Dscam_C PF12355.3 EMR62726.1 - 0.087 13.0 0.5 11 6.3 0.1 2.4 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal NmrA PF05368.8 EMR62727.1 - 4e-16 58.9 0.0 7.4e-15 54.8 0.0 2.0 1 1 1 2 2 2 1 NmrA-like family KR PF08659.5 EMR62727.1 - 0.001 18.8 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR62727.1 - 0.0013 18.7 0.0 0.0081 16.1 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMR62727.1 - 0.031 14.2 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase TFR_dimer PF04253.10 EMR62729.1 - 1.1e-22 79.9 0.1 1.8e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EMR62729.1 - 4.1e-16 59.2 0.0 8.9e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMR62729.1 - 2.3e-07 30.4 0.2 4e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 PA domain Pex26 PF07163.7 EMR62729.1 - 0.093 11.6 0.5 0.21 10.4 0.0 1.6 2 0 0 2 2 2 0 Pex26 protein PhyH PF05721.8 EMR62730.1 - 6.5e-35 121.0 0.0 8.1e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) BBE PF08031.7 EMR62730.1 - 0.041 13.7 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 Berberine and berberine like DUF1479 PF07350.7 EMR62730.1 - 0.1 11.0 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) AMP-binding PF00501.23 EMR62731.1 - 2.6e-106 355.4 0.0 4.2e-106 354.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EMR62731.1 - 1.5e-87 293.2 0.3 3e-87 292.3 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMR62731.1 - 2.9e-66 223.9 0.0 6.5e-66 222.8 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EMR62731.1 - 1.3e-63 213.9 1.0 3.4e-61 206.0 0.8 2.9 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EMR62731.1 - 9.7e-57 191.5 0.6 4.1e-54 182.9 0.8 3.0 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EMR62731.1 - 3.4e-50 170.2 0.0 8.6e-49 165.7 0.0 2.4 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EMR62731.1 - 8.9e-47 157.8 0.5 1.9e-46 156.7 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EMR62731.1 - 1.1e-22 80.0 0.0 2e-11 43.9 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 EMR62731.1 - 2.9e-14 53.0 0.0 2e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EMR62731.1 - 1e-07 32.7 0.0 2.8e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.18 EMR62731.1 - 5.8e-06 25.4 0.4 1.2e-05 24.4 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain NmrA PF05368.8 EMR62731.1 - 0.0011 18.2 0.3 0.85 8.8 0.0 2.6 2 0 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.14 EMR62731.1 - 0.0015 17.2 0.1 0.74 8.4 0.0 2.5 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMR62731.1 - 0.0026 17.8 2.5 0.038 14.0 0.0 3.3 3 1 0 3 3 3 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMR62731.1 - 0.026 13.4 0.0 0.4 9.5 0.0 2.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Ribosomal_L30 PF00327.15 EMR62731.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e PTS-HPr PF00381.14 EMR62731.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 PTS HPr component phosphorylation site RasGAP_C PF03836.10 EMR62732.1 - 5.4e-47 159.0 1.9 1.7e-46 157.4 1.3 2.0 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EMR62732.1 - 1.4e-42 145.5 0.0 3.8e-42 144.1 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EMR62732.1 - 2.5e-29 98.0 39.7 0.0018 17.7 0.1 15.1 15 0 0 15 15 15 10 IQ calmodulin-binding motif CH PF00307.26 EMR62732.1 - 3.9e-10 39.7 0.0 1.2e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain MFS_1 PF07690.11 EMR62733.1 - 2.8e-31 108.5 47.3 3.5e-25 88.4 8.3 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR62733.1 - 3.1e-11 42.5 5.8 3.1e-11 42.5 4.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MtrG PF04210.8 EMR62733.1 - 0.079 12.6 0.4 4.3 7.0 0.4 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Herpes_capsid PF06112.6 EMR62733.1 - 1.8 8.5 11.6 3.5 7.6 8.1 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF508 PF04370.7 EMR62733.1 - 7.7 6.1 8.9 13 5.3 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) SR-25 PF10500.4 EMR62733.1 - 8.1 5.8 12.6 12 5.2 8.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein E1-E2_ATPase PF00122.15 EMR62734.1 - 7.9e-53 178.8 0.2 7.9e-53 178.8 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EMR62734.1 - 9.6e-46 156.8 0.3 1.7e-45 156.0 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EMR62734.1 - 5.9e-17 61.5 0.0 1.4e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 EMR62734.1 - 7.5e-15 55.6 0.0 1.5e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMR62734.1 - 4.7e-06 26.3 3.5 0.0002 21.0 0.8 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 EMR62735.1 - 3.6e-13 48.9 0.0 7.3e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA PF00004.24 EMR62736.1 - 5.7e-13 49.2 0.0 2.5e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMR62736.1 - 0.0012 18.9 0.3 0.0046 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EMR62736.1 - 0.034 13.8 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EMR62736.1 - 0.038 14.1 0.1 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EMR62736.1 - 0.04 13.8 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Nucleoplasmin PF03066.10 EMR62736.1 - 0.14 11.6 6.9 0.3 10.5 4.8 1.5 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EMR62736.1 - 1.1 8.8 5.0 2.2 7.8 3.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 EMR62736.1 - 4.4 5.9 15.7 8.5 4.9 10.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 EMR62736.1 - 9.4 5.3 8.3 16 4.6 5.8 1.3 1 0 0 1 1 1 0 NOA36 protein APH PF01636.18 EMR62737.1 - 1.2e-11 44.8 0.1 2.6e-11 43.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMR62737.1 - 0.0047 16.5 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EMR62737.1 - 0.01 14.4 0.0 0.015 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RIO1 PF01163.17 EMR62737.1 - 0.078 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family IMPDH PF00478.20 EMR62738.1 - 2.3e-130 434.6 2.6 2.8e-130 434.3 1.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EMR62738.1 - 1.6e-13 50.1 0.0 1.4e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EMR62738.1 - 3.4e-09 36.0 0.7 1e-08 34.4 0.1 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EMR62738.1 - 3.7e-08 32.9 7.5 0.0019 17.4 0.0 2.6 3 0 0 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 EMR62738.1 - 0.00013 21.3 2.2 0.0015 17.8 1.5 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 EMR62738.1 - 0.0027 16.8 1.3 0.15 11.1 0.4 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Gly_transf_sug PF04488.10 EMR62739.1 - 1e-16 61.2 0.0 1.6e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMR62739.1 - 0.08 11.4 0.4 0.13 10.7 0.3 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain PAD PF03068.10 EMR62740.1 - 1.7e-51 174.8 0.0 6.3e-35 120.3 0.0 2.1 2 0 0 2 2 2 2 Protein-arginine deiminase (PAD) DUF3180 PF11377.3 EMR62740.1 - 0.23 11.2 1.5 0.28 11.0 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) UPF0052 PF01933.13 EMR62741.1 - 2e-49 168.5 0.0 1.9e-48 165.3 0.0 2.3 2 1 0 2 2 2 1 Uncharacterised protein family UPF0052 MSP1_C PF07462.6 EMR62741.1 - 2.9 6.1 4.1 13 3.9 2.9 1.9 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus MCPVI PF02993.9 EMR62742.1 - 9.9 6.2 15.4 18 5.3 10.7 1.4 1 0 0 1 1 1 0 Minor capsid protein VI Ldh_1_N PF00056.18 EMR62743.1 - 3.5e-43 146.8 0.0 6.3e-43 145.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EMR62743.1 - 1.2e-42 145.5 0.0 1.9e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EMR62743.1 - 0.00043 19.0 0.0 0.00065 18.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EMR62743.1 - 0.079 13.2 0.2 0.43 10.9 0.0 2.3 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain GSH_synth_ATP PF03917.12 EMR62744.1 - 1.9e-74 250.5 0.0 8.1e-74 248.4 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EMR62744.1 - 9.4e-21 73.8 0.0 1.5e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF2599 PF10783.4 EMR62744.1 - 0.12 12.9 0.0 0.23 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2599) APH PF01636.18 EMR62745.1 - 0.0013 18.5 1.7 0.0013 18.5 1.2 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Abhydrolase_6 PF12697.2 EMR62746.1 - 1.4e-18 67.6 6.9 2.3e-18 66.9 4.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EMR62746.1 - 4.9e-15 55.4 2.2 1.8e-06 27.3 2.0 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_5 PF12695.2 EMR62746.1 - 2.2e-14 53.4 1.6 4.2e-14 52.5 1.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR62746.1 - 0.00032 20.0 0.3 0.21 10.7 0.4 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EMR62746.1 - 0.001 18.6 2.2 0.0079 15.7 1.2 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 EMR62746.1 - 0.011 15.0 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family HEAT PF02985.17 EMR62748.1 - 1.1e-14 53.1 16.4 0.0026 17.6 0.0 10.3 12 0 0 12 12 12 3 HEAT repeat HEAT_2 PF13646.1 EMR62748.1 - 1.1e-14 54.3 8.2 1.7e-06 28.2 0.0 6.9 1 1 5 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 EMR62748.1 - 1.3e-14 54.1 3.3 3.3e-08 33.7 0.0 7.5 6 1 2 8 8 8 1 HEAT-like repeat IBN_N PF03810.14 EMR62748.1 - 2.1e-09 37.1 3.3 2.1e-09 37.1 2.3 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF3554 PF12074.3 EMR62748.1 - 1e-05 25.1 5.5 3.3e-05 23.5 0.3 3.7 2 2 1 4 4 4 1 Domain of unknown function (DUF3554) CLASP_N PF12348.3 EMR62748.1 - 0.00014 21.2 5.4 3.1 7.0 0.0 6.0 3 2 3 7 7 7 2 CLASP N terminal RIX1 PF08167.7 EMR62748.1 - 0.0036 16.9 2.0 0.69 9.5 0.0 4.7 2 1 3 6 6 6 1 rRNA processing/ribosome biogenesis DUF1981 PF09324.5 EMR62748.1 - 0.008 15.6 1.0 4.8 6.7 0.0 4.7 4 1 2 6 6 6 1 Domain of unknown function (DUF1981) DUF1548 PF07579.6 EMR62748.1 - 0.12 12.4 2.2 0.81 9.8 0.1 3.1 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1548) RsbRD_N PF14361.1 EMR62748.1 - 9.7 6.7 11.1 4.1 7.8 1.7 4.3 5 1 1 6 6 6 0 RsbT co-antagonist protein rsbRD N-terminal domain HMGL-like PF00682.14 EMR62749.1 - 2.2e-57 194.4 0.0 4e-57 193.5 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EMR62749.1 - 9.7e-23 80.4 0.0 2e-22 79.4 0.0 1.5 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain Ribosomal_S9 PF00380.14 EMR62750.1 - 8.4e-40 135.7 0.4 9.5e-40 135.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 O-antigen_lig PF13425.1 EMR62751.1 - 0.047 13.6 1.4 0.053 13.4 0.1 1.6 1 1 1 2 2 2 0 O-antigen ligase like membrane protein Lactate_perm PF02652.9 EMR62751.1 - 0.15 10.5 0.0 0.19 10.1 0.0 1.2 1 1 0 1 1 1 0 L-lactate permease Acyl_transf_3 PF01757.17 EMR62751.1 - 0.16 10.7 6.6 0.21 10.4 4.6 1.2 1 0 0 1 1 1 0 Acyltransferase family DUF4131 PF13567.1 EMR62751.1 - 1.8 7.9 7.4 13 5.1 5.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) AAR2 PF05282.6 EMR62752.1 - 2.1e-48 165.1 0.0 5.8e-48 163.6 0.0 1.6 1 1 0 1 1 1 1 AAR2 protein S1 PF00575.18 EMR62753.1 - 5e-85 279.6 40.4 5.3e-14 52.0 0.3 13.2 13 0 0 13 13 13 12 S1 RNA binding domain TPR_14 PF13428.1 EMR62753.1 - 1.8e-05 24.9 7.9 2.8 8.8 0.0 6.0 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMR62753.1 - 0.00061 20.0 5.0 2.6 8.4 0.2 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMR62753.1 - 0.0014 19.2 4.0 0.11 13.1 0.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMR62753.1 - 0.0018 18.3 0.3 3.1 8.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMR62753.1 - 0.019 15.4 3.3 7.9 7.1 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Suf PF05843.9 EMR62753.1 - 0.063 13.0 7.3 0.18 11.5 0.2 3.2 2 1 1 3 3 3 0 Suppressor of forked protein (Suf) Lactonase PF10282.4 EMR62754.1 - 0.00017 20.7 0.0 0.78 8.7 0.0 3.8 2 2 1 3 3 3 2 Lactonase, 7-bladed beta-propeller Methyltransf_16 PF10294.4 EMR62755.1 - 7.6e-29 100.3 0.0 1.6e-28 99.3 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EMR62755.1 - 6.5e-05 22.7 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR62755.1 - 0.0052 17.3 0.0 0.02 15.4 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EMR62755.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Apt1 PF10351.4 EMR62756.1 - 8.9e-173 575.3 0.8 8.9e-173 575.3 0.5 1.7 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27 PF10344.4 EMR62756.1 - 1.1e-165 552.7 0.0 2e-165 551.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.4 EMR62756.1 - 1.8e-151 504.7 0.7 1.8e-151 504.7 0.5 1.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EMR62756.1 - 3.1e-54 183.1 0.0 7.7e-54 181.8 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EMR62756.1 - 5.7e-34 117.1 0.0 1.5e-33 115.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EMR62756.1 - 1.5e-33 115.2 0.1 8.1e-33 112.9 0.0 2.4 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain HsbA PF12296.3 EMR62756.1 - 0.22 11.3 2.6 1.3 8.8 0.0 3.0 3 0 0 3 3 3 0 Hydrophobic surface binding protein A EAP30 PF04157.11 EMR62757.1 - 3.3e-64 216.1 0.0 4e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Acyl-CoA_dh_1 PF00441.19 EMR62758.1 - 9.3e-34 116.7 3.7 9.3e-34 116.7 2.6 2.2 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMR62758.1 - 2.1e-19 70.1 2.2 6.1e-19 68.6 1.5 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EMR62758.1 - 1.6e-15 56.3 0.1 1e-14 53.7 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMR62758.1 - 3.4e-15 56.4 4.9 3.4e-15 56.4 3.4 2.8 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Sulfate_transp PF00916.15 EMR62759.1 - 8.7e-64 215.2 11.6 1.6e-63 214.3 8.0 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMR62759.1 - 5.6e-29 99.6 1.5 5.6e-29 99.6 1.0 3.2 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMR62759.1 - 9.4e-09 34.7 0.0 1.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EMR62759.1 - 0.034 14.1 2.4 0.34 10.9 0.1 2.7 2 0 0 2 2 2 0 STAS domain DUF1700 PF08006.6 EMR62759.1 - 1.9 7.7 10.8 7.6 5.7 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) ADH_N PF08240.7 EMR62760.1 - 6.1e-30 103.1 1.7 1.4e-29 102.0 1.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR62760.1 - 5.2e-15 55.1 0.0 7.5e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EMR62760.1 - 0.0073 16.3 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 EMR62760.1 - 0.047 13.7 1.0 4.5 7.4 0.4 2.5 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Ribosomal_L36 PF00444.13 EMR62760.1 - 0.98 9.4 4.6 0.26 11.3 0.3 2.1 2 0 0 2 2 2 0 Ribosomal protein L36 ATP-sulfurylase PF01747.12 EMR62761.1 - 1.7e-87 292.2 0.0 2.4e-87 291.7 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EMR62761.1 - 1.8e-55 186.9 0.0 2.9e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EMR62761.1 - 3.4e-54 182.5 0.0 5.3e-54 181.9 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Mucin PF01456.12 EMR62762.1 - 8.5e-06 25.5 10.3 2.2e-05 24.2 7.1 1.7 1 0 0 1 1 1 1 Mucin-like glycoprotein PAN_4 PF14295.1 EMR62762.1 - 0.0021 17.7 1.9 0.004 16.8 1.3 1.4 1 0 0 1 1 1 1 PAN domain ODV-E18 PF10717.4 EMR62762.1 - 0.074 12.4 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2140 PF09911.4 EMR62762.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) SpoIIIAH PF12685.2 EMR62762.1 - 0.73 9.2 2.9 0.28 10.6 0.2 1.5 2 0 0 2 2 2 0 SpoIIIAH-like protein BAF1_ABF1 PF04684.8 EMR62762.1 - 4.8 5.9 7.8 8.4 5.1 5.4 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Kinocilin PF15033.1 EMR62763.1 - 0.8 9.2 4.4 1.2 8.7 0.2 2.5 2 0 0 2 2 2 0 Kinocilin protein Ribosomal_60s PF00428.14 EMR62763.1 - 1 9.7 36.3 0.3 11.5 4.3 4.1 4 0 0 4 4 4 0 60s Acidic ribosomal protein Ldh_1_N PF00056.18 EMR62764.1 - 5.7e-43 146.1 0.1 8e-43 145.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EMR62764.1 - 1.9e-41 141.6 0.0 2.7e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EMR62764.1 - 0.0019 16.9 0.0 0.0027 16.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pectate_lyase_3 PF12708.2 EMR62765.1 - 2.4e-32 112.9 16.2 5.6e-23 82.2 3.9 2.7 3 1 0 3 3 3 2 Pectate lyase superfamily protein Ribosomal_L28e PF01778.12 EMR62766.1 - 6.3e-41 139.4 0.3 8e-41 139.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.5 EMR62767.1 - 9.8e-48 161.1 0.0 1.1e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) FA_hydroxylase PF04116.8 EMR62768.1 - 1.9e-13 50.8 22.0 1.3e-12 48.1 12.0 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily WD40 PF00400.27 EMR62769.1 - 3.3e-71 232.8 11.8 1.4e-10 40.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EMR62769.1 - 1.5e-21 76.3 11.4 2.4e-21 75.6 7.9 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 EMR62769.1 - 0.00077 17.7 1.2 0.28 9.2 0.0 3.6 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMR62769.1 - 0.0081 14.9 0.1 0.76 8.4 0.1 3.1 1 1 1 2 2 2 1 Nup133 N terminal like Nbas_N PF15492.1 EMR62769.1 - 0.042 12.9 0.1 19 4.2 0.0 3.2 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 EMR62769.1 - 0.044 12.0 0.2 0.73 8.0 0.1 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain LXG PF04740.7 EMR62769.1 - 0.047 13.4 2.7 0.07 12.9 1.8 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Laminin_II PF06009.7 EMR62769.1 - 0.35 10.6 2.0 0.52 10.0 1.4 1.2 1 0 0 1 1 1 0 Laminin Domain II Glyco_hydro_76 PF03663.9 EMR62770.1 - 5.6e-53 180.6 3.4 6.8e-53 180.3 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1680 PF07944.7 EMR62770.1 - 0.00094 17.5 0.0 0.52 8.5 0.0 2.2 1 1 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_88 PF07470.8 EMR62770.1 - 0.01 14.8 0.1 0.3 10.0 0.0 2.3 1 1 0 2 2 2 0 Glycosyl Hydrolase Family 88 DUF1183 PF06682.7 EMR62771.1 - 1e-77 261.9 4.4 1.3e-77 261.5 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) EGF_CA PF07645.10 EMR62771.1 - 0.033 14.1 1.0 0.068 13.1 0.7 1.5 1 0 0 1 1 1 0 Calcium-binding EGF domain DUF202 PF02656.10 EMR62771.1 - 0.11 12.6 0.2 0.47 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Aminotran_3 PF00202.16 EMR62772.1 - 5.4e-95 318.1 0.0 6.6e-95 317.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III ABC_membrane PF00664.18 EMR62773.1 - 1.3e-85 287.1 41.5 4.4e-44 150.9 10.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMR62773.1 - 1.2e-67 226.4 0.0 1.7e-33 115.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMR62773.1 - 4.2e-12 45.7 0.0 0.0004 19.6 0.0 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMR62773.1 - 1.2e-09 38.5 0.2 0.36 10.7 0.0 4.3 2 2 1 3 3 3 3 AAA domain AAA_29 PF13555.1 EMR62773.1 - 6.7e-09 35.1 1.6 0.00018 20.9 0.2 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EMR62773.1 - 4e-07 30.8 0.0 0.044 14.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EMR62773.1 - 4.5e-07 28.8 3.5 0.0094 14.5 0.1 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EMR62773.1 - 8.3e-07 28.3 0.0 0.14 11.3 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMR62773.1 - 2e-06 27.8 5.7 0.0076 16.2 0.0 3.4 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 EMR62773.1 - 0.00014 22.0 0.6 1.7 8.8 0.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EMR62773.1 - 0.00079 18.8 6.9 0.35 10.2 0.0 3.9 5 0 0 5 5 5 2 AAA domain SbcCD_C PF13558.1 EMR62773.1 - 0.00082 19.2 2.6 1.2 9.0 0.1 3.6 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EMR62773.1 - 0.0019 18.4 0.0 2.4 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EMR62773.1 - 0.0039 17.0 0.0 2.1 8.2 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.1 EMR62773.1 - 0.0046 16.9 0.6 0.65 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EMR62773.1 - 0.0048 17.2 0.0 0.3 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMR62773.1 - 0.0049 16.7 0.0 5.4 6.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMR62773.1 - 0.0082 15.8 0.5 9.4 5.9 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EMR62773.1 - 0.011 15.5 3.3 1.4 8.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EMR62773.1 - 0.017 14.6 0.1 0.5 9.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family G-alpha PF00503.15 EMR62773.1 - 0.018 13.7 0.0 2 7.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DUF815 PF05673.8 EMR62773.1 - 0.034 13.0 0.0 3.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 EMR62773.1 - 0.076 12.4 2.8 14 4.9 0.3 3.6 4 0 0 4 4 4 0 AAA-like domain MobB PF03205.9 EMR62773.1 - 0.098 12.3 1.8 15 5.2 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EMR62773.1 - 0.11 12.4 0.1 8.9 6.3 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 EMR62773.1 - 0.17 12.0 0.1 15 5.7 0.0 2.9 2 0 0 2 2 2 0 RNA helicase BRE1 PF08647.6 EMR62774.1 - 7.9e-23 80.2 6.4 7.9e-23 80.2 4.4 6.3 4 2 2 6 6 6 1 BRE1 E3 ubiquitin ligase Reo_sigmaC PF04582.7 EMR62774.1 - 0.0087 15.2 28.5 0.021 14.0 2.2 4.4 3 2 1 4 4 4 4 Reovirus sigma C capsid protein Filament PF00038.16 EMR62774.1 - 1 8.7 63.2 3.5 6.9 29.4 5.5 2 1 1 3 3 3 0 Intermediate filament protein Pectate_lyase_3 PF12708.2 EMR62775.1 - 7.5e-82 274.7 26.8 1.7e-66 224.5 9.2 3.2 2 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EMR62775.1 - 5.5e-06 25.7 1.2 0.053 12.9 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Serglycin PF04360.7 EMR62775.1 - 6.8 6.4 9.1 0.72 9.5 2.5 2.1 3 0 0 3 3 3 0 Serglycin Rab5-bind PF09311.6 EMR62776.1 - 0.0022 17.9 12.1 0.0028 17.5 8.4 1.1 1 0 0 1 1 1 1 Rabaptin-like protein Jnk-SapK_ap_N PF09744.4 EMR62776.1 - 0.0053 16.7 10.6 0.0071 16.3 7.3 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 APG6 PF04111.7 EMR62776.1 - 0.0083 15.2 3.9 0.011 14.8 2.7 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 TMPIT PF07851.8 EMR62776.1 - 0.62 9.0 2.2 0.33 9.9 0.4 1.3 2 0 0 2 2 2 0 TMPIT-like protein SlyX PF04102.7 EMR62776.1 - 0.76 10.1 7.9 0.29 11.5 2.1 2.5 1 1 0 2 2 2 0 SlyX BTV_NS2 PF04514.7 EMR62776.1 - 1.3 7.8 8.7 1.6 7.5 6.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Atg14 PF10186.4 EMR62776.1 - 2.4 7.0 9.6 8.6 5.2 6.0 1.7 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EMR62776.1 - 3.3 6.2 9.5 7.6 5.0 6.7 1.4 1 1 1 2 2 2 0 Spc7 kinetochore protein SRI PF08236.6 EMR62778.1 - 2.9e-22 78.3 10.1 7.7e-22 77.0 7.0 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 EMR62778.1 - 3.2e-20 73.0 0.2 3.2e-20 73.0 0.2 3.8 3 2 0 3 3 3 1 SET domain WW PF00397.21 EMR62778.1 - 0.0032 17.3 1.2 0.0071 16.1 0.8 1.7 1 0 0 1 1 1 1 WW domain Hydantoinase_B PF02538.9 EMR62778.1 - 0.046 11.9 1.2 0.058 11.6 0.0 1.6 2 0 0 2 2 2 0 Hydantoinase B/oxoprolinase Smoothelin PF12510.3 EMR62778.1 - 0.22 11.4 8.1 2.3 8.1 2.8 2.9 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein Myb_DNA-binding PF00249.26 EMR62779.1 - 3.9e-06 26.8 0.0 9.3e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMR62779.1 - 0.0048 16.9 0.4 0.019 15.0 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain TAT_signal PF10518.4 EMR62779.1 - 0.047 13.7 2.3 0.11 12.5 1.6 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Scs3p PF10261.4 EMR62781.1 - 2.6e-64 216.5 0.8 3.4e-64 216.1 0.5 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM XPC-binding PF09280.6 EMR62782.1 - 1.1e-24 85.6 12.9 1.7e-24 85.0 9.0 1.3 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EMR62782.1 - 3.5e-19 67.9 0.6 5.3e-19 67.3 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EMR62782.1 - 1.4e-18 66.1 3.9 3.3e-09 36.3 0.2 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EMR62782.1 - 3.9e-10 39.2 0.5 7.3e-10 38.4 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 EMR62782.1 - 0.0008 18.9 0.0 0.38 10.3 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain DUF2407 PF10302.4 EMR62782.1 - 0.0039 17.3 0.0 0.0099 16.0 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain MCM_N PF14551.1 EMR62782.1 - 0.006 17.0 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 MCM N-terminal domain Rad60-SLD_2 PF13881.1 EMR62782.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 EMR62782.1 - 0.049 13.1 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 CUE domain Phosphodiest PF01663.17 EMR62783.1 - 8.2e-11 41.8 0.4 1.5e-10 41.0 0.3 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMR62783.1 - 4.8e-05 22.6 0.0 8.3e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EMR62783.1 - 0.00023 20.6 0.4 0.00039 19.9 0.2 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.12 EMR62783.1 - 0.51 8.7 0.0 0.72 8.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) LTV PF04180.9 EMR62784.1 - 8.4e-99 331.9 10.9 1e-98 331.6 7.5 1.1 1 0 0 1 1 1 1 Low temperature viability protein M16C_assoc PF08367.6 EMR62785.1 - 5.4e-59 199.0 0.0 8e-59 198.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EMR62785.1 - 6.2e-36 123.7 0.0 8.3e-21 74.4 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMR62785.1 - 3.6e-07 30.0 0.0 1.4e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Acyltransferase PF01553.16 EMR62786.1 - 0.073 12.5 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Acyltransferase Aldo_ket_red PF00248.16 EMR62787.1 - 4.3e-57 193.1 0.0 5e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acyl_transf_1 PF00698.16 EMR62788.1 - 4.6e-62 210.1 0.0 7.5e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EMR62788.1 - 4.5e-60 202.4 1.0 1.6e-59 200.6 0.7 2.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR62788.1 - 5e-49 166.4 1.3 5e-49 166.4 0.9 3.2 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 EMR62788.1 - 4.1e-45 154.1 0.0 6.4e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EMR62788.1 - 3.5e-34 117.2 0.0 1.4e-33 115.2 0.0 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EMR62788.1 - 1.7e-25 89.9 0.0 4.3e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ADH_zinc_N PF00107.21 EMR62788.1 - 9.2e-19 67.2 0.2 5.7e-18 64.7 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR62788.1 - 1.1e-12 48.9 0.0 7.7e-12 46.2 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR62788.1 - 1.1e-09 37.9 1.4 2.4e-09 36.9 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 EMR62788.1 - 4.3e-05 23.0 0.7 0.0063 15.9 0.1 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMR62788.1 - 0.0019 18.4 1.1 0.0088 16.2 0.3 2.5 3 0 0 3 3 3 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 EMR62788.1 - 0.0032 16.4 0.0 0.0075 15.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMR62788.1 - 0.018 15.0 1.2 0.23 11.4 0.1 2.8 2 0 0 2 2 2 0 NADH(P)-binding Saccharop_dh PF03435.13 EMR62788.1 - 0.036 13.0 0.6 2.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NmrA PF05368.8 EMR62788.1 - 0.039 13.1 0.1 0.083 12.1 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family Shikimate_DH PF01488.15 EMR62788.1 - 0.071 13.2 0.3 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase RelA_SpoT PF04607.12 EMR62789.1 - 0.00059 19.8 0.1 0.016 15.2 0.0 2.8 2 1 0 2 2 2 1 Region found in RelA / SpoT proteins Orn_Arg_deC_N PF02784.11 EMR62790.1 - 7e-77 257.9 0.0 9.5e-77 257.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EMR62790.1 - 1.6e-30 105.2 0.1 2.8e-30 104.4 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain tRNA-synt_2 PF00152.15 EMR62791.1 - 2.6e-63 213.8 0.6 2.4e-62 210.6 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMR62791.1 - 8.1e-05 22.4 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ComFB PF10719.4 EMR62791.1 - 0.0051 16.5 1.9 0.0079 15.9 0.3 2.0 1 1 1 2 2 2 1 Late competence development protein ComFB Peptidase_M16_C PF05193.16 EMR62792.1 - 1.6e-24 86.6 0.0 2.2e-17 63.3 0.0 3.7 3 0 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMR62792.1 - 5e-06 26.3 0.0 2.9e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DDE_Tnp_IS1 PF03400.8 EMR62792.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 IS1 transposase CDC45 PF02724.9 EMR62792.1 - 0.2 9.6 3.8 0.33 8.9 2.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EMR62792.1 - 0.78 9.2 9.2 2 7.9 6.4 1.6 1 0 0 1 1 1 0 Nucleoplasmin M16C_assoc PF08367.6 EMR62792.1 - 1.1 8.0 6.3 10 4.8 0.0 2.4 2 0 0 2 2 2 0 Peptidase M16C associated Cu-oxidase_3 PF07732.10 EMR62793.1 - 2.3e-31 107.9 0.5 1.1e-30 105.7 0.0 2.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EMR62793.1 - 7.2e-26 90.9 0.0 2.4e-25 89.2 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMR62793.1 - 6.5e-24 84.0 2.3 8.1e-20 70.7 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase adh_short PF00106.20 EMR62794.1 - 1.8e-06 28.0 0.0 3.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR62794.1 - 0.0019 17.8 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR62794.1 - 0.012 15.3 0.1 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMR62794.1 - 0.066 13.2 0.0 0.73 9.8 0.0 2.5 1 1 0 1 1 1 0 NADH(P)-binding NAD_binding_4 PF07993.7 EMR62794.1 - 0.066 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Taxilin PF09728.4 EMR62795.1 - 2.9e-79 266.3 58.6 3.6e-52 177.3 29.0 2.3 2 0 0 2 2 2 2 Myosin-like coiled-coil protein TMF_TATA_bd PF12325.3 EMR62795.1 - 0.00035 20.2 47.6 0.052 13.2 1.6 4.7 3 1 1 4 4 4 3 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 EMR62795.1 - 0.0017 18.1 6.2 0.0017 18.1 4.3 4.8 2 1 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_MT_bd PF06657.8 EMR62795.1 - 0.002 18.0 2.8 0.002 18.0 1.9 3.4 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 GAS PF13851.1 EMR62795.1 - 0.0056 15.9 6.6 0.0056 15.9 4.6 4.1 2 1 2 4 4 4 1 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.14 EMR62795.1 - 0.023 12.4 59.3 0.013 13.3 2.4 2.0 2 0 0 2 2 2 0 Myosin tail IncA PF04156.9 EMR62795.1 - 0.035 13.6 0.2 0.035 13.6 0.1 4.3 2 1 1 3 3 3 0 IncA protein DUF1654 PF07867.6 EMR62795.1 - 0.041 13.2 1.9 0.19 11.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) ABC_membrane PF00664.18 EMR62796.1 - 8.4e-24 84.4 9.4 1.2e-23 83.9 6.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Lysis_S PF04971.7 EMR62796.1 - 0.13 11.9 1.2 1.9 8.2 0.3 2.8 2 0 0 2 2 2 0 Lysis protein S FHA PF00498.21 EMR62797.1 - 1.1e-08 35.0 0.1 1.9e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 FHA domain Pkinase PF00069.20 EMR62797.1 - 5e-05 22.5 0.0 9e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain ILVD_EDD PF00920.16 EMR62798.1 - 2.3e-210 699.4 0.4 2.9e-210 699.1 0.3 1.1 1 0 0 1 1 1 1 Dehydratase family GTP_EFTU_D4 PF14578.1 EMR62798.1 - 0.072 12.7 2.8 7.4 6.2 0.0 3.6 3 0 0 3 3 3 0 Elongation factor Tu domain 4 Phosphonate-bd PF12974.2 EMR62799.1 - 2.4e-05 23.8 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.6 EMR62799.1 - 0.00026 20.6 0.0 0.0065 16.0 0.0 2.4 1 1 1 2 2 2 2 NMT1/THI5 like SBP_bac_3 PF00497.15 EMR62799.1 - 0.00071 18.8 0.0 0.004 16.4 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 PC_rep PF01851.17 EMR62799.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Proteasome/cyclosome repeat adh_short PF00106.20 EMR62800.1 - 7e-28 97.6 0.7 8.8e-28 97.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR62800.1 - 1.6e-18 67.4 0.0 1.9e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR62800.1 - 4.2e-07 29.8 0.2 6.9e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EMR62800.1 - 6.2e-05 22.7 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EMR62800.1 - 0.00019 21.5 0.2 0.004 17.1 0.2 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR62800.1 - 0.00022 20.7 0.0 0.00044 19.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.10 EMR62800.1 - 0.00043 19.9 0.0 0.00068 19.3 0.0 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.14 EMR62800.1 - 0.013 14.5 0.1 0.033 13.2 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.10 EMR62800.1 - 0.017 14.0 0.0 0.021 13.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.5 EMR62800.1 - 0.025 13.7 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) UDPG_MGDP_dh_N PF03721.9 EMR62800.1 - 0.032 13.6 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RmlD_sub_bind PF04321.12 EMR62800.1 - 0.04 12.7 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Methyltransf_26 PF13659.1 EMR62800.1 - 0.054 13.5 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 3Beta_HSD PF01073.14 EMR62800.1 - 0.054 12.1 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 EMR62800.1 - 0.069 13.5 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain AlaDh_PNT_C PF01262.16 EMR62800.1 - 0.072 12.6 0.2 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EMR62800.1 - 0.074 13.0 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Ldh_1_N PF00056.18 EMR62800.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.8 EMR62801.1 - 1.7e-09 37.5 0.0 3.2e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_2 PF00891.13 EMR62802.1 - 4.4e-27 94.8 0.0 7.4e-27 94.0 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EMR62802.1 - 0.00078 20.0 0.0 0.0013 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Glyco_hydro_31 PF01055.21 EMR62803.1 - 4.2e-153 510.3 1.7 5.5e-153 509.9 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMR62803.1 - 1.7e-23 82.2 0.3 4.1e-23 81.0 0.2 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like NDK PF00334.14 EMR62804.1 - 5.5e-54 181.6 0.0 6.2e-54 181.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_tran_28_C PF04101.11 EMR62805.1 - 1.2e-09 38.0 0.1 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.13 EMR62805.1 - 1.2e-08 33.9 0.1 2.2e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Fungal_trans PF04082.13 EMR62806.1 - 2.6e-10 39.6 5.4 8.1e-10 38.0 3.8 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR62806.1 - 2.9e-10 39.9 10.4 2.9e-10 39.9 7.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MinE PF03776.9 EMR62806.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE FLILHELTA PF10306.4 EMR62807.1 - 8.2e-20 70.6 0.0 1.4e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EMR62807.1 - 0.02 15.1 0.0 0.039 14.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) MMR_HSR1 PF01926.18 EMR62808.1 - 2.6e-17 62.8 0.2 2.4e-15 56.5 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMR62808.1 - 3.1e-07 29.7 0.3 1.7e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EMR62808.1 - 0.0002 20.5 0.0 0.00037 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EMR62808.1 - 0.00088 19.1 1.0 0.069 12.9 0.2 2.7 2 1 0 2 2 2 1 Dynamin family AIG1 PF04548.11 EMR62808.1 - 0.0028 16.7 0.1 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EMR62808.1 - 0.041 14.3 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein CNTF PF01110.12 EMR62808.1 - 0.092 12.0 1.3 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Ciliary neurotrophic factor MMR_HSR1 PF01926.18 EMR62809.1 - 0.0002 21.2 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Methyltransf_29 PF03141.11 EMR62809.1 - 0.029 12.7 0.0 0.05 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Dynamin_N PF00350.18 EMR62809.1 - 0.25 11.1 0.0 0.25 11.1 0.0 3.0 2 2 0 2 2 2 0 Dynamin family Phytase PF02333.10 EMR62810.1 - 6.5e-33 113.9 6.4 7.7e-29 100.5 0.5 3.0 2 1 1 3 3 3 2 Phytase EGF_2 PF07974.8 EMR62810.1 - 0.17 12.0 6.5 0.33 11.1 4.5 1.5 1 0 0 1 1 1 0 EGF-like domain Hydrolase_6 PF13344.1 EMR62811.1 - 5.8e-22 77.5 0.0 1.1e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR62811.1 - 2.7e-18 65.4 0.0 8.4e-18 63.8 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EMR62811.1 - 0.00041 20.6 0.1 0.075 13.2 0.0 2.9 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR62811.1 - 0.0047 17.3 0.0 0.28 11.5 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EMR62811.1 - 0.16 11.3 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Cupin_2 PF07883.6 EMR62812.1 - 0.00037 19.9 0.1 0.0014 18.1 0.0 1.9 2 0 0 2 2 2 1 Cupin domain DUF4390 PF14334.1 EMR62812.1 - 0.04 13.1 0.0 0.09 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) Med13_C PF06333.7 EMR62813.1 - 0.19 10.2 7.5 0.23 9.9 5.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Kinesin PF00225.18 EMR62814.1 - 8.1e-86 287.7 0.0 8.1e-86 287.7 0.0 1.7 2 1 0 2 2 2 1 Kinesin motor domain DEAD PF00270.24 EMR62814.1 - 0.0067 15.9 0.0 0.79 9.1 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase Laminin_II PF06009.7 EMR62814.1 - 0.025 14.3 25.1 0.28 10.9 7.9 3.8 1 1 3 4 4 4 0 Laminin Domain II Tropomyosin PF00261.15 EMR62814.1 - 0.046 12.8 57.0 0.69 8.9 35.5 4.0 1 1 2 3 3 3 0 Tropomyosin AAA_22 PF13401.1 EMR62814.1 - 0.078 13.1 6.9 0.12 12.5 0.0 3.6 2 1 1 3 3 3 0 AAA domain AdoHcyase_NAD PF00670.16 EMR62814.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Reo_sigmaC PF04582.7 EMR62814.1 - 0.17 11.0 3.0 1.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EMR62814.1 - 0.62 9.8 50.3 0.016 14.9 6.6 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein MFS_1 PF07690.11 EMR62815.1 - 4e-46 157.3 50.1 1.4e-45 155.5 34.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR62815.1 - 1.6e-08 33.2 22.4 2.4e-08 32.6 15.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMR62815.1 - 8.9e-05 21.2 37.7 9.8e-05 21.1 9.4 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter EXS PF03124.9 EMR62815.1 - 0.05 12.6 0.5 0.11 11.5 0.2 1.5 1 1 0 1 1 1 0 EXS family Cerato-platanin PF07249.7 EMR62817.1 - 0.00012 22.0 1.9 0.00013 21.9 0.1 1.9 2 1 1 3 3 3 1 Cerato-platanin Pyridoxal_deC PF00282.14 EMR62818.1 - 2.2e-113 378.4 0.0 2.6e-113 378.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain GTP1_OBG PF01018.17 EMR62818.1 - 1.2 8.7 10.2 1.7 8.2 1.4 2.5 2 0 0 2 2 2 0 GTP1/OBG EIF_2_alpha PF07541.7 EMR62819.1 - 1.3e-37 128.0 0.0 2.3e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EMR62819.1 - 2.3e-13 49.9 0.7 5.2e-13 48.8 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DUF1013 PF06242.6 EMR62819.1 - 0.086 12.8 0.2 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) Ras PF00071.17 EMR62820.1 - 9.1e-65 216.9 0.0 1.1e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR62820.1 - 3.3e-19 69.5 0.0 5.2e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMR62820.1 - 2.5e-13 49.6 0.0 3.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMR62820.1 - 2.7e-06 26.9 0.1 4.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMR62820.1 - 9.8e-06 24.8 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMR62820.1 - 0.003 17.5 0.2 0.0078 16.1 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.15 EMR62820.1 - 0.03 13.0 0.5 3 6.4 0.1 2.7 1 1 1 2 2 2 0 G-protein alpha subunit DUF2589 PF11655.3 EMR62820.1 - 0.033 14.3 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2589) FeoB_N PF02421.13 EMR62820.1 - 0.038 13.2 0.0 0.19 11.0 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 EMR62820.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 EMR62820.1 - 0.12 12.5 0.0 6.2 7.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR62820.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain NCA2 PF08637.5 EMR62821.1 - 9.6e-92 306.9 0.1 1.8e-91 306.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.1 EMR62821.1 - 0.24 10.1 0.1 0.4 9.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Imm41 PF15583.1 EMR62822.1 - 0.056 13.2 0.1 0.94 9.2 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 41 SE PF08491.5 EMR62825.1 - 2.2e-83 279.2 0.0 3e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EMR62825.1 - 4e-12 45.8 0.1 1e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR62825.1 - 3.4e-10 39.3 1.5 2.4e-08 33.2 0.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EMR62825.1 - 5.4e-05 22.3 0.0 0.0001 21.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EMR62825.1 - 7e-05 22.7 0.4 0.0002 21.3 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMR62825.1 - 0.00014 20.8 0.1 0.00027 19.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EMR62825.1 - 0.00017 20.6 0.6 0.00085 18.2 0.4 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EMR62825.1 - 0.0002 20.3 0.5 0.018 13.9 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.13 EMR62825.1 - 0.00042 20.0 0.1 0.00069 19.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMR62825.1 - 0.0006 19.9 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EMR62825.1 - 0.00072 19.9 0.1 0.0015 18.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMR62825.1 - 0.00094 18.3 1.7 0.0044 16.1 1.5 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.11 EMR62825.1 - 0.0017 17.7 0.1 0.0029 17.0 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 EMR62825.1 - 0.0034 17.2 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EMR62825.1 - 0.005 16.5 0.1 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 EMR62825.1 - 0.063 13.1 0.4 0.13 12.0 0.3 1.5 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.9 EMR62825.1 - 0.075 11.4 0.2 0.11 10.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FA_hydroxylase PF04116.8 EMR62826.1 - 2.4e-14 53.6 21.6 2.4e-14 53.6 15.0 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily AAA PF00004.24 EMR62827.1 - 4.1e-52 175.8 0.0 6.2e-40 136.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EMR62827.1 - 9.6e-08 31.9 0.0 0.0025 17.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMR62827.1 - 1.7e-06 28.2 0.0 0.017 15.2 0.0 3.8 3 2 1 4 4 4 2 AAA domain AAA_16 PF13191.1 EMR62827.1 - 3e-06 27.3 1.1 0.024 14.6 0.1 4.2 2 2 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 EMR62827.1 - 1.1e-05 24.9 0.9 0.37 10.1 0.0 4.0 2 2 2 4 4 4 2 AAA domain AAA_5 PF07728.9 EMR62827.1 - 2.2e-05 24.2 0.1 0.0078 15.9 0.0 3.5 3 2 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EMR62827.1 - 2.6e-05 24.1 0.0 0.0015 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EMR62827.1 - 3e-05 24.0 0.0 0.038 13.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EMR62827.1 - 0.00012 22.1 0.0 0.68 10.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 EMR62827.1 - 0.0002 21.0 0.3 0.18 11.4 0.0 3.3 2 1 1 3 3 3 1 NACHT domain AAA_2 PF07724.9 EMR62827.1 - 0.00028 20.8 0.0 0.003 17.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EMR62827.1 - 0.0017 17.4 0.0 0.065 12.2 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMR62827.1 - 0.0018 18.0 0.0 0.076 12.7 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 EMR62827.1 - 0.003 16.7 0.2 0.32 10.1 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EMR62827.1 - 0.0034 16.4 0.0 4 6.4 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_17 PF13207.1 EMR62827.1 - 0.0062 17.3 0.0 1.9 9.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain CDC48_N PF02359.13 EMR62827.1 - 0.0097 15.8 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain TIP49 PF06068.8 EMR62827.1 - 0.019 13.7 0.0 0.067 11.8 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus Arch_ATPase PF01637.13 EMR62827.1 - 0.064 12.9 0.0 1.1 8.8 0.0 2.6 2 1 0 2 2 2 0 Archaeal ATPase DAP3 PF10236.4 EMR62827.1 - 0.23 10.3 0.0 2.9 6.7 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 KaiC PF06745.8 EMR62827.1 - 0.31 10.1 0.9 66 2.5 0.0 3.1 2 1 1 3 3 3 0 KaiC Mito_carr PF00153.22 EMR62828.1 - 8.1e-45 150.4 0.7 9.4e-20 70.1 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Lipase_GDSL_2 PF13472.1 EMR62829.1 - 2.9e-16 60.1 0.1 3.7e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMR62829.1 - 2e-12 47.4 0.0 3e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MRP-L51 PF10244.4 EMR62829.1 - 0.032 14.2 0.1 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit Peptidase_S24 PF00717.18 EMR62830.1 - 7.1e-06 25.5 0.0 1.5e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EMR62830.1 - 0.0018 17.7 0.0 0.02 14.3 0.0 2.1 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 SR-25 PF10500.4 EMR62831.1 - 0.063 12.7 32.2 0.82 9.1 1.4 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Pterin_4a PF01329.14 EMR62832.1 - 1.8e-06 27.5 0.0 2.2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DnaJ PF00226.26 EMR62834.1 - 1.5e-11 43.8 0.0 2.3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Peptidase_M43 PF05572.8 EMR62835.1 - 1.9e-13 50.2 0.0 2.9e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EMR62835.1 - 0.0013 18.7 0.3 0.002 18.0 0.2 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 EMR62835.1 - 0.0019 17.9 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.1 EMR62835.1 - 0.0023 17.9 0.2 0.0046 17.0 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMR62835.1 - 0.0052 16.3 0.1 0.0099 15.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EMR62835.1 - 0.029 13.2 0.4 0.046 12.5 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 LNS2 PF08235.8 EMR62836.1 - 3.6e-69 231.3 0.0 5.8e-69 230.6 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EMR62836.1 - 2.4e-39 133.4 0.0 1.4e-38 130.9 0.0 2.1 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EMR62836.1 - 0.00036 19.9 0.0 0.091 12.1 0.0 2.6 2 0 0 2 2 2 2 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.16 EMR62837.1 - 2.5e-09 37.1 0.0 5.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain DUF3584 PF12128.3 EMR62837.1 - 1.3 6.3 34.6 2 5.6 24.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Amidohydro_1 PF01979.15 EMR62838.1 - 1.8e-28 100.1 0.9 2.4e-28 99.7 0.7 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMR62838.1 - 1.5e-06 28.5 13.2 1.2e-05 25.5 9.1 2.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EMR62838.1 - 3.7e-06 26.6 0.0 1.5e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EMR62838.1 - 0.00089 18.5 4.4 0.021 14.0 0.9 2.6 2 1 0 2 2 2 2 Amidohydrolase family SSXT PF05030.7 EMR62839.1 - 0.0007 19.1 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Met_10 PF02475.11 EMR62839.1 - 0.00081 19.0 0.0 0.0057 16.2 0.0 2.1 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EMR62839.1 - 0.0064 16.5 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Pkinase_Tyr PF07714.12 EMR62840.1 - 0.04 12.9 0.0 3 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Luteo_Vpg PF01659.11 EMR62841.1 - 0.011 15.3 1.0 0.019 14.6 0.7 1.3 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein CAP59_mtransfer PF11735.3 EMR62842.1 - 8.2e-78 260.9 0.0 1.1e-77 260.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 zf-H2C2_2 PF13465.1 EMR62843.1 - 1.9e-15 56.2 8.7 2.1e-08 34.0 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EMR62843.1 - 9.6e-14 50.8 12.2 3.2e-06 27.1 1.6 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR62843.1 - 4.3e-12 45.4 12.3 1.6e-05 24.9 1.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMR62843.1 - 8.5e-09 35.3 1.6 0.012 15.7 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMR62843.1 - 6.9e-06 26.0 2.3 0.0056 16.8 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EMR62843.1 - 0.033 14.3 1.6 0.06 13.4 1.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EMR62843.1 - 0.063 13.1 7.9 4.4 7.3 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger LIM PF00412.17 EMR62843.1 - 0.15 12.1 4.0 2.6 8.1 2.9 2.4 1 1 1 2 2 2 0 LIM domain Elf1 PF05129.8 EMR62843.1 - 0.16 11.7 1.2 0.36 10.5 0.8 1.6 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Corona_nucleoca PF00937.13 EMR62843.1 - 0.27 10.1 5.2 0.44 9.4 3.6 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Zn_ribbon_recom PF13408.1 EMR62843.1 - 0.29 11.4 2.9 0.18 12.0 0.4 1.9 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C2H2_2 PF12756.2 EMR62843.1 - 0.56 10.3 2.8 2.1 8.5 0.1 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.16 EMR62843.1 - 2.4 8.1 6.8 4.7 7.1 4.7 1.6 1 1 0 1 1 1 0 FYVE zinc finger zf-BED PF02892.10 EMR62843.1 - 3.7 7.3 7.2 81 3.0 3.7 2.9 1 1 0 1 1 1 0 BED zinc finger LSM PF01423.17 EMR62844.1 - 2.7e-19 68.4 0.1 3.1e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMR62844.1 - 0.00045 20.0 0.1 0.00052 19.8 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain IceA2 PF05862.6 EMR62844.1 - 0.084 12.5 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein SpoA PF01052.15 EMR62844.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) Rad60-SLD PF11976.3 EMR62846.1 - 4.2e-17 61.5 0.3 9.2e-17 60.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Pol_alpha_B_N PF08418.5 EMR62846.1 - 0.33 10.4 13.9 0.28 10.6 8.0 1.9 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF4246 PF14033.1 EMR62847.1 - 5.6e-150 500.2 0.0 8.5e-109 364.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) DUF3272 PF11676.3 EMR62847.1 - 0.099 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3272) AroM PF07302.6 EMR62847.1 - 0.21 10.8 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 AroM protein MDM31_MDM32 PF08118.6 EMR62848.1 - 2.8e-184 613.2 0.0 1.9e-183 610.5 0.0 1.8 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Trypan_PARP PF05887.6 EMR62849.1 - 5.4e-05 23.0 88.5 0.00012 21.8 25.4 21.2 8 5 12 21 21 21 6 Procyclic acidic repetitive protein (PARP) adh_short PF00106.20 EMR62850.1 - 1.4e-05 25.0 0.9 1.6e-05 24.8 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR62850.1 - 0.00046 19.9 0.3 0.00056 19.6 0.2 1.1 1 0 0 1 1 1 1 KR domain eIF3_subunit PF08597.5 EMR62851.1 - 5.1e-69 232.5 20.8 5.6e-69 232.4 14.4 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CodY PF06018.9 EMR62851.1 - 0.087 12.1 0.2 1.5 8.1 0.0 2.3 1 1 1 2 2 2 0 CodY GAF-like domain MRP-S31 PF15433.1 EMR62851.1 - 0.29 10.5 10.9 0.95 8.8 3.2 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 PRP4 PF08799.6 EMR62851.1 - 0.49 9.7 3.1 0.94 8.8 2.2 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Spore_coat_CotO PF14153.1 EMR62851.1 - 0.57 9.5 14.6 0.027 13.8 5.2 1.9 2 0 0 2 2 2 0 Spore coat protein CotO CDC27 PF09507.5 EMR62851.1 - 3.8 6.6 25.2 0.22 10.7 11.4 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 GAGA_bind PF06217.7 EMR62851.1 - 6.6 6.6 10.5 1.1 9.1 2.5 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family KH_1 PF00013.24 EMR62852.1 - 0.00013 21.5 1.0 0.00032 20.2 0.7 1.6 1 0 0 1 1 1 1 KH domain Methyltransf_11 PF08241.7 EMR62853.1 - 5e-12 46.1 0.0 1.2e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR62853.1 - 3.7e-05 22.9 0.0 5.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EMR62853.1 - 4.4e-05 24.0 0.0 8.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR62853.1 - 9.3e-05 22.8 0.0 0.00024 21.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR62853.1 - 0.0002 21.1 0.0 0.00032 20.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR62853.1 - 0.00022 21.2 0.1 0.00055 19.9 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF3197 PF11432.3 EMR62853.1 - 0.023 14.6 0.2 0.052 13.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) Methyltransf_31 PF13847.1 EMR62853.1 - 0.044 13.3 0.0 0.39 10.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain W_rich_C PF07483.6 EMR62853.1 - 0.045 13.4 0.5 5.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain Methyltransf_25 PF13649.1 EMR62853.1 - 0.046 14.0 0.0 0.084 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Tim17 PF02466.14 EMR62854.1 - 3.3e-28 98.2 0.8 5.2e-28 97.6 0.5 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family AOX PF01786.12 EMR62856.1 - 5.7e-63 212.0 0.3 7.6e-34 116.9 0.1 2.0 1 1 1 2 2 2 2 Alternative oxidase LSM PF01423.17 EMR62858.1 - 1.6e-16 59.5 0.4 2.2e-16 59.1 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMR62858.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.3 EMR62858.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Rrn6 PF10214.4 EMR62859.1 - 0.9 7.5 6.9 1.4 6.9 4.8 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor NAD_binding_10 PF13460.1 EMR62860.1 - 6.3e-10 39.3 0.0 6.2e-09 36.1 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR62860.1 - 2.1e-06 27.3 0.0 3.5e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR62860.1 - 0.0011 17.7 0.0 0.0016 17.1 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EMR62860.1 - 0.0094 15.2 0.1 0.014 14.6 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EMR62860.1 - 0.069 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MS_channel PF00924.13 EMR62861.1 - 5.3e-17 61.8 4.0 9.4e-17 61.0 2.8 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EMR62861.1 - 0.0032 16.6 0.1 0.0084 15.3 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EMR62861.1 - 0.0049 16.1 0.1 0.012 14.8 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EMR62861.1 - 0.029 14.2 0.0 0.091 12.6 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 EMR62861.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Spore_YabQ PF09578.5 EMR62861.1 - 0.064 13.2 9.7 0.52 10.2 1.0 2.5 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) VIT1 PF01988.14 EMR62861.1 - 2.7 7.4 7.7 0.51 9.7 0.2 2.3 2 0 0 2 2 2 0 VIT family His_Phos_1 PF00300.17 EMR62863.1 - 1.1e-13 51.5 0.0 1.6e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Aldo_ket_red PF00248.16 EMR62865.1 - 1.4e-52 178.3 0.0 1.6e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Thi4 PF01946.12 EMR62865.1 - 0.067 12.2 0.0 0.15 11.0 0.0 1.6 1 0 0 1 1 1 0 Thi4 family GMC_oxred_N PF00732.14 EMR62867.1 - 3.3e-49 167.6 0.0 3.9e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMR62867.1 - 4.6e-06 25.7 0.0 0.0028 16.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR62867.1 - 1.5e-05 24.0 0.0 0.0056 15.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 EMR62867.1 - 2.3e-05 23.4 1.2 0.12 11.1 0.3 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EMR62867.1 - 4.8e-05 22.4 0.0 6.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMR62867.1 - 0.0018 18.1 0.2 0.0066 16.3 0.1 2.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR62867.1 - 0.0021 18.0 0.1 0.0053 16.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMR62867.1 - 0.0072 16.1 0.2 0.016 14.9 0.1 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EMR62867.1 - 0.01 14.3 0.1 0.074 11.5 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 EMR62867.1 - 0.027 14.5 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR62867.1 - 0.071 13.5 0.7 0.14 12.6 0.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMR62867.1 - 0.092 11.3 0.5 0.13 10.8 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 EMR62867.1 - 0.51 9.3 2.8 1 8.3 1.9 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_24 PF13578.1 EMR62868.1 - 0.032 15.0 0.0 0.1 13.4 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain SSP160 PF06933.6 EMR62868.1 - 0.049 11.6 1.3 0.066 11.1 0.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Methyltransf_18 PF12847.2 EMR62868.1 - 0.13 12.8 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EMR62869.1 - 3.6e-27 95.3 0.1 4.3e-27 95.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR62869.1 - 1e-20 74.5 0.0 1.3e-20 74.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR62869.1 - 4.6e-12 45.9 0.1 6.2e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR62869.1 - 0.0063 16.5 0.2 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF236 PF03057.9 EMR62869.1 - 0.0076 16.2 0.1 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function YjeF_N PF03853.10 EMR62869.1 - 0.012 15.1 0.1 0.019 14.5 0.1 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus T2SE PF00437.15 EMR62870.1 - 0.077 11.8 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PIG-P PF08510.7 EMR62872.1 - 0.019 14.5 0.8 0.035 13.7 0.6 1.5 1 0 0 1 1 1 0 PIG-P PilM_2 PF11104.3 EMR62872.1 - 0.17 10.7 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; GMC_oxred_N PF00732.14 EMR62873.1 - 6.3e-59 199.5 0.0 1.2e-58 198.6 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR62873.1 - 8.6e-37 126.6 0.2 1.7e-36 125.6 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMR62873.1 - 2.1e-05 23.6 0.2 0.00083 18.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR62873.1 - 8.1e-05 21.6 0.1 0.0026 16.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EMR62873.1 - 0.00013 21.0 0.1 0.0002 20.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMR62873.1 - 0.00015 21.7 0.1 0.00038 20.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR62873.1 - 0.0006 19.7 0.0 0.0016 18.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMR62873.1 - 0.011 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EMR62873.1 - 0.016 13.7 0.0 0.021 13.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EMR62873.1 - 0.032 14.6 0.2 0.1 13.0 0.0 2.0 3 0 0 3 3 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR62873.1 - 0.039 14.0 0.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMR62873.1 - 0.069 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 EMR62873.1 - 0.084 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EMR62873.1 - 0.11 11.1 0.1 0.18 10.4 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Tyr-DNA_phospho PF06087.7 EMR62874.1 - 7.8e-27 93.9 0.0 1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EMR62874.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain DUF1680 PF07944.7 EMR62876.1 - 4.5e-17 61.5 0.0 8.7e-17 60.5 0.0 1.3 1 1 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_3_C PF01915.17 EMR62877.1 - 5e-55 186.5 0.1 6.4e-55 186.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR62877.1 - 9.1e-15 54.3 0.1 3.3e-14 52.5 0.1 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EMR62877.1 - 2.5e-11 43.4 0.3 7.7e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 PA14 domain DUF11 PF01345.13 EMR62877.1 - 0.0026 17.7 0.7 0.01 15.8 0.5 2.0 1 0 0 1 1 1 1 Domain of unknown function DUF11 CARDB PF07705.6 EMR62877.1 - 0.014 15.4 0.4 0.092 12.8 0.2 2.5 2 1 1 3 3 3 0 CARDB Wzt_C PF14524.1 EMR62877.1 - 0.045 13.4 0.1 9.8 5.8 0.0 2.7 3 0 0 3 3 3 0 Wzt C-terminal domain DUF3488 PF11992.3 EMR62878.1 - 0.01 14.4 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) zf-C2H2_4 PF13894.1 EMR62880.1 - 7.9e-07 28.9 13.2 0.0041 17.3 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMR62880.1 - 1e-05 25.5 11.0 0.14 12.5 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMR62880.1 - 0.01 16.0 6.4 0.03 14.6 0.5 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 EMR62880.1 - 0.016 15.0 0.4 0.22 11.4 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Cation_efflux PF01545.16 EMR62881.1 - 1.2e-74 250.9 4.7 1.5e-74 250.6 3.3 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EMR62881.1 - 0.0019 17.3 8.3 0.002 17.2 5.1 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Clp1 PF06807.9 EMR62882.1 - 5.6e-19 68.6 0.0 1.8e-17 63.7 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MMR_HSR1 PF01926.18 EMR62882.1 - 8.2e-07 28.9 0.0 6.9e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EMR62882.1 - 5.3e-06 26.1 0.0 9.4e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EMR62882.1 - 0.00013 21.6 0.0 0.00059 19.4 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 EMR62882.1 - 0.0038 17.1 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EMR62882.1 - 0.005 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMR62882.1 - 0.005 17.6 0.0 0.014 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EMR62882.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 EMR62882.1 - 0.028 14.7 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 EMR62882.1 - 0.045 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein ArgK PF03308.11 EMR62882.1 - 0.067 11.9 0.2 0.11 11.2 0.1 1.3 1 0 0 1 1 1 0 ArgK protein Dynamin_N PF00350.18 EMR62882.1 - 0.069 12.9 0.0 4.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Dynamin family AAA_16 PF13191.1 EMR62882.1 - 0.082 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PPC PF04151.10 EMR62882.1 - 0.097 13.6 0.5 0.097 13.6 0.4 2.9 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain DUF258 PF03193.11 EMR62882.1 - 0.11 11.6 0.0 4.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 KTI12 PF08433.5 EMR62882.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Arb1 PF09692.5 EMR62883.1 - 8.9e-103 344.1 0.0 1.1e-102 343.8 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.11 EMR62884.1 - 2.9e-48 164.1 0.0 3.8e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase NdhM PF10664.4 EMR62884.1 - 0.041 13.7 0.6 0.38 10.7 0.2 2.4 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M Methyltransf_2 PF00891.13 EMR62885.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF3608 PF12257.3 EMR62886.1 - 8.8e-61 205.2 0.1 3.1e-60 203.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EMR62886.1 - 4.1e-30 103.3 0.1 9.3e-30 102.2 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) adh_short PF00106.20 EMR62887.1 - 1.7e-18 67.0 0.1 2.6e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR62887.1 - 5.9e-08 32.5 0.1 9.4e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR62887.1 - 7.7e-08 32.3 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR62887.1 - 9.7e-06 25.1 0.1 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR62887.1 - 0.0011 17.9 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein FGGY_N PF00370.16 EMR62887.1 - 0.012 14.9 0.2 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain CENP-H PF05837.7 EMR62887.1 - 0.013 15.6 1.9 0.017 15.3 0.2 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Polysacc_synt_2 PF02719.10 EMR62887.1 - 0.014 14.3 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1537 PF07005.6 EMR62887.1 - 0.067 12.8 0.0 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF1537 DUF1342 PF07072.6 EMR62887.1 - 0.075 12.6 0.2 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1342) adh_short_C2 PF13561.1 EMR62888.1 - 2.3e-25 89.7 0.0 4.1e-13 49.6 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR62888.1 - 1.4e-22 80.4 1.9 1.4e-21 77.1 1.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR62888.1 - 1.1e-11 44.6 0.1 1.6e-11 44.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR62888.1 - 9e-05 22.0 0.0 0.0036 16.7 0.0 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EMR62888.1 - 0.0052 16.0 0.2 0.023 13.9 0.2 1.9 1 1 0 1 1 1 1 NmrA-like family YjeF_N PF03853.10 EMR62888.1 - 0.042 13.4 0.2 0.068 12.7 0.2 1.5 1 1 0 1 1 1 0 YjeF-related protein N-terminus DFP PF04127.10 EMR62888.1 - 0.13 11.8 3.6 1.9 8.1 2.5 2.2 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Na_Ca_ex PF01699.19 EMR62889.1 - 1.5e-37 128.3 30.4 2.3e-20 72.6 9.1 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF1180 PF06679.7 EMR62889.1 - 0.21 11.4 0.3 20 5.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Tad PF13400.1 EMR62889.1 - 0.24 11.4 11.1 3.1 7.9 0.1 4.4 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like DUF1996 PF09362.5 EMR62890.1 - 1.2e-75 254.2 0.0 1.3e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) A2L_zn_ribbon PF08792.5 EMR62891.1 - 5.6 6.5 6.7 4.6 6.8 0.5 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain CAP PF00188.21 EMR62892.1 - 1.1e-22 80.7 5.1 1.5e-22 80.3 3.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MCPVI PF02993.9 EMR62892.1 - 2.2 8.3 8.2 3.3 7.7 5.7 1.3 1 0 0 1 1 1 0 Minor capsid protein VI ADH_zinc_N PF00107.21 EMR62893.1 - 9.9e-10 38.0 0.1 1.9e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR62893.1 - 1.1e-05 25.0 0.0 2.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EMR62893.1 - 0.00039 20.4 2.7 0.0019 18.2 0.0 2.7 2 1 0 3 3 3 1 NADH(P)-binding ADH_zinc_N_2 PF13602.1 EMR62893.1 - 0.00049 20.9 0.1 0.0013 19.6 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.8 EMR62893.1 - 0.00096 18.4 2.9 0.0024 17.1 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family AlaDh_PNT_C PF01262.16 EMR62893.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.20 EMR62893.1 - 0.2 11.5 4.0 0.72 9.7 0.2 2.4 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_10 PF13460.1 EMR62894.1 - 1.8e-07 31.3 0.0 2.5e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR62894.1 - 1.1e-05 24.9 0.0 1.7e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR62894.1 - 0.00015 20.7 0.0 0.026 13.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein DapB_N PF01113.15 EMR62894.1 - 0.0021 17.9 0.0 0.0055 16.6 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 EMR62894.1 - 0.0029 16.3 0.0 0.0093 14.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EMR62894.1 - 0.0061 15.8 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EMR62894.1 - 0.017 15.4 0.0 0.077 13.3 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EMR62894.1 - 0.16 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PNGaseA PF12222.3 EMR62895.1 - 1.8e-131 438.9 1.8 2.2e-131 438.6 1.2 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Het-C PF07217.6 EMR62897.1 - 3.8e-40 137.6 0.1 4.6e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Peptidase_M28 PF04389.12 EMR62898.1 - 1.7e-33 115.8 0.0 4e-33 114.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 DUF1725 PF08333.6 EMR62898.1 - 0.96 8.8 2.6 7.3 6.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) SinI PF08671.5 EMR62899.1 - 0.21 11.0 2.4 0.63 9.5 1.3 2.1 2 0 0 2 2 2 0 Anti-repressor SinI DUF1656 PF07869.7 EMR62899.1 - 0.78 9.5 4.9 0.35 10.6 1.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) CDP-OH_P_transf PF01066.16 EMR62900.1 - 7.2e-18 64.7 2.3 7.2e-18 64.7 1.6 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ribophorin_II PF05817.9 EMR62902.1 - 8e-21 73.9 0.7 4.1e-20 71.5 0.5 1.8 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Glyco_transf_15 PF01793.11 EMR62904.1 - 3.7e-130 433.7 0.4 4.8e-130 433.3 0.3 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EcKinase PF02958.15 EMR62905.1 - 4.2e-17 62.2 0.0 8.7e-11 41.4 0.0 2.1 2 0 0 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.6 EMR62905.1 - 3.1e-09 35.9 0.0 4.5e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.18 EMR62905.1 - 1.2e-07 31.7 0.9 1.9e-07 31.0 0.6 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family AAA PF00004.24 EMR62906.1 - 2.6e-05 24.4 0.0 6.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pribosyltran_N PF13793.1 EMR62907.1 - 6.4e-41 138.7 0.0 1.6e-40 137.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EMR62907.1 - 3.3e-34 118.2 0.0 1.5e-28 99.8 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EMR62907.1 - 8.4e-06 25.5 0.2 0.021 14.5 0.0 2.7 3 0 0 3 3 3 2 Phosphoribosyl transferase domain Fungal_trans PF04082.13 EMR62908.1 - 1.3e-29 102.9 0.0 2.2e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EMR62910.1 - 4.8e-33 114.4 0.2 5.6e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR62910.1 - 1.5e-12 47.5 0.0 1.8e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR62910.1 - 2.1e-11 44.0 0.0 2.7e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EMR62910.1 - 0.0058 16.4 0.5 0.026 14.2 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AAA_17 PF13207.1 EMR62911.1 - 1.6e-07 32.1 0.2 5e-06 27.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMR62911.1 - 0.00017 21.8 0.1 0.00062 20.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 EMR62911.1 - 0.00022 20.8 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 EMR62911.1 - 0.00053 20.0 0.1 0.0013 18.7 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EMR62911.1 - 0.00058 19.0 0.0 0.00096 18.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EMR62911.1 - 0.00058 19.7 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EMR62911.1 - 0.00095 18.1 0.0 0.007 15.2 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein NB-ARC PF00931.17 EMR62911.1 - 0.0018 17.2 0.0 0.0025 16.7 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EMR62911.1 - 0.0088 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 EMR62911.1 - 0.013 15.2 0.1 0.039 13.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EMR62911.1 - 0.014 15.5 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EMR62911.1 - 0.017 14.8 0.1 0.025 14.2 0.1 1.2 1 0 0 1 1 1 0 NTPase Thymidylate_kin PF02223.12 EMR62911.1 - 0.053 12.8 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase cobW PF02492.14 EMR62911.1 - 0.053 12.9 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 EMR62911.1 - 0.057 12.9 0.1 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.5 EMR62911.1 - 0.066 12.4 0.0 0.092 11.9 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 EMR62911.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain GvpD PF07088.6 EMR62911.1 - 0.092 11.0 0.0 0.094 11.0 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein MobB PF03205.9 EMR62911.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EMR62911.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 ArgK protein PRELI PF04707.9 EMR62913.1 - 1.2e-42 145.1 0.2 1.4e-42 144.9 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.9 EMR62913.1 - 0.031 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_M24 PF00557.19 EMR62914.1 - 6.8e-40 136.8 0.1 8.8e-40 136.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Methyltransf_11 PF08241.7 EMR62915.1 - 1e-05 25.9 0.0 6.9e-05 23.2 0.0 2.3 2 1 1 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR62915.1 - 0.00016 20.8 0.1 0.0027 16.8 0.0 2.3 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EMR62915.1 - 0.016 14.7 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EMR62915.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Gln-synt_C PF00120.19 EMR62916.1 - 2.6e-51 174.2 0.0 3.8e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EMR62916.1 - 2.1e-26 93.1 0.3 1.3e-25 90.5 0.0 2.3 3 0 0 3 3 3 1 Amidohydrolase TraW_N PF12477.3 EMR62916.1 - 0.78 9.7 3.8 0.35 10.8 0.6 1.9 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal 3Beta_HSD PF01073.14 EMR62917.1 - 7e-53 179.1 0.3 8.9e-53 178.8 0.2 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMR62917.1 - 2.3e-30 105.7 0.1 2.9e-30 105.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR62917.1 - 7.2e-13 48.0 0.4 8.2e-08 31.4 0.1 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EMR62917.1 - 1e-06 27.8 0.1 2e-06 26.9 0.1 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EMR62917.1 - 3.2e-05 22.9 1.1 3.2e-05 22.9 0.8 2.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EMR62917.1 - 0.00025 21.0 0.3 0.001 19.0 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMR62917.1 - 0.00034 20.6 0.0 0.00061 19.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMR62917.1 - 0.09 12.4 0.9 1.2 8.7 0.6 2.3 1 1 0 1 1 1 0 KR domain MSP1_C PF07462.6 EMR62919.1 - 6.1 5.1 5.0 1.6 7.0 0.6 1.9 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Pkinase PF00069.20 EMR62921.1 - 2.4e-34 118.6 0.0 3.8e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR62921.1 - 6.9e-21 74.4 0.0 9.5e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Beta-lactamase PF00144.19 EMR62922.1 - 1.7e-32 112.7 1.5 3.5e-18 65.7 0.1 2.1 1 1 1 2 2 2 2 Beta-lactamase Peptidase_S11 PF00768.15 EMR62922.1 - 0.034 13.4 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Peptidase_S13 PF02113.10 EMR62922.1 - 0.053 12.0 0.1 0.078 11.4 0.1 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family p450 PF00067.17 EMR62923.1 - 1.9e-47 161.8 0.0 1.8e-46 158.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Aminotran_3 PF00202.16 EMR62924.1 - 8.2e-36 123.5 0.1 9.4e-36 123.3 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_3 PF00202.16 EMR62925.1 - 4.2e-11 42.3 0.0 9.6e-11 41.1 0.0 1.5 1 1 1 2 2 2 1 Aminotransferase class-III GST_N PF02798.15 EMR62926.1 - 1.5e-09 37.8 0.0 3.8e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMR62926.1 - 6e-09 36.2 0.1 9.6e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMR62926.1 - 6.8e-09 35.5 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMR62926.1 - 1.8e-08 34.4 0.0 3.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMR62926.1 - 2e-08 34.1 0.0 4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR62926.1 - 6e-08 32.4 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ADH_zinc_N PF00107.21 EMR62927.1 - 1.5e-30 105.4 0.6 2.5e-30 104.6 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR62927.1 - 3.5e-15 57.0 0.1 1.2e-14 55.3 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EMR62927.1 - 0.00027 20.9 0.0 0.00059 19.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ADH_N PF08240.7 EMR62927.1 - 0.0073 16.0 0.1 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 EMR62927.1 - 0.059 12.9 0.1 0.093 12.2 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 EMR62927.1 - 0.076 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Myb_DNA-bind_4 PF13837.1 EMR62928.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EMR62928.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain PDZ_1 PF12812.2 EMR62929.1 - 2.8e-52 174.5 0.1 4.7e-32 109.7 0.0 2.8 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EMR62929.1 - 1.6e-15 56.7 0.3 3.5e-07 30.0 0.0 4.5 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 EMR62929.1 - 2.9e-15 56.2 0.2 2.1e-12 47.0 0.0 2.8 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ PF00595.19 EMR62929.1 - 9.8e-12 44.8 0.0 1.9e-05 24.7 0.0 4.0 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EMR62929.1 - 5e-05 23.0 0.6 0.014 15.1 0.0 3.5 3 0 0 3 3 3 1 Tricorn protease PDZ domain Trypsin PF00089.21 EMR62929.1 - 0.00026 20.6 0.0 0.0007 19.2 0.0 1.7 1 0 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.16 EMR62929.1 - 0.16 11.3 0.2 0.44 9.9 0.1 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease FAM196 PF15265.1 EMR62930.1 - 0.75 8.9 16.8 0.95 8.6 11.6 1.1 1 0 0 1 1 1 0 FAM196 family MAP65_ASE1 PF03999.7 EMR62930.1 - 2.3 6.7 11.0 3.3 6.1 7.6 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) MIP-T3 PF10243.4 EMR62930.1 - 4.2 5.7 10.3 5.3 5.3 7.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Plasmodium_Vir PF05795.6 EMR62930.1 - 6 5.9 7.3 7.8 5.5 5.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pollen_allerg_2 PF01620.11 EMR62931.1 - 9.7 6.5 12.3 4.9 7.4 0.5 2.1 1 1 1 2 2 2 0 Ribonuclease (pollen allergen) HsbA PF12296.3 EMR62932.1 - 0.0011 18.8 0.1 0.002 17.9 0.1 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Pneumo_att_G PF05539.6 EMR62932.1 - 9.8 5.4 9.9 15 4.7 6.9 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF3176 PF11374.3 EMR62933.1 - 8.3e-25 86.8 0.4 1.7e-24 85.8 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) EOS1 PF12326.3 EMR62933.1 - 0.035 13.7 0.0 0.087 12.4 0.0 1.6 1 0 0 1 1 1 0 N-glycosylation protein DUF4588 PF15251.1 EMR62934.1 - 9.5e-06 25.7 8.4 2.5e-05 24.3 5.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) MFS_1 PF07690.11 EMR62935.1 - 1.2e-31 109.7 47.2 2.2e-20 72.7 8.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR62935.1 - 4.2e-09 35.3 22.0 6.6e-08 31.3 11.3 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein SNF2_N PF00176.18 EMR62936.1 - 3.4e-83 278.8 0.3 3.4e-83 278.8 0.2 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 EMR62936.1 - 1.7e-45 153.5 4.1 4.1e-45 152.3 2.9 1.7 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 EMR62936.1 - 4.9e-32 110.6 3.7 4.9e-32 110.6 2.5 3.4 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 EMR62936.1 - 3e-15 55.8 0.0 8.6e-15 54.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR62936.1 - 4e-07 30.0 3.2 5.2e-07 29.6 0.0 3.0 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMR62936.1 - 3.5e-05 23.3 0.0 8.9e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 EMR62936.1 - 0.0039 17.2 0.0 0.13 12.3 0.0 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain DEAD_2 PF06733.10 EMR62936.1 - 0.027 13.8 0.1 0.059 12.7 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 EMR62936.1 - 0.03 14.2 0.2 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain p450 PF00067.17 EMR62937.1 - 9.3e-38 129.9 0.0 2e-35 122.2 0.0 2.9 1 1 1 2 2 2 2 Cytochrome P450 Rho_N PF07498.7 EMR62938.1 - 0.034 13.9 0.1 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain WD40 PF00400.27 EMR62939.1 - 4.4e-31 105.6 1.0 1.4e-11 43.8 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 EMR62939.1 - 0.0064 14.6 0.0 0.0081 14.3 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Gmad1 PF10647.4 EMR62939.1 - 0.0078 15.6 1.7 0.03 13.7 0.3 1.9 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain eIF2A PF08662.6 EMR62939.1 - 0.011 15.4 0.2 0.46 10.1 0.1 2.7 1 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EMR62939.1 - 0.026 13.9 0.2 0.54 9.6 0.1 2.4 1 1 0 1 1 1 0 PQQ-like domain Nucleoporin_N PF08801.6 EMR62939.1 - 0.039 12.7 0.0 0.14 10.8 0.0 1.8 1 1 0 1 1 1 0 Nup133 N terminal like Peptidase_S9 PF00326.16 EMR62940.1 - 1.7e-35 122.2 0.0 2.7e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.16 EMR62940.1 - 0.00027 19.6 0.3 0.0044 15.6 0.1 2.4 1 1 1 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 EMR62940.1 - 0.0048 16.5 1.1 0.63 9.7 0.0 3.3 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Arylesterase PF01731.15 EMR62940.1 - 0.1 12.5 0.1 3.2 7.8 0.0 3.2 3 0 0 3 3 3 0 Arylesterase F-box-like PF12937.2 EMR62941.1 - 3.5e-06 26.6 0.1 9.3e-06 25.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMR62941.1 - 0.006 16.2 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain Sulfate_transp PF00916.15 EMR62942.1 - 0.064 12.2 18.0 0.026 13.5 8.0 3.1 1 1 2 3 3 3 0 Sulfate transporter family Fork_head PF00250.13 EMR62943.1 - 5.8e-13 48.7 0.0 1.4e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EMR62943.1 - 5.8e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain DUF2132 PF09905.4 EMR62943.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2132) Closter_coat PF01785.12 EMR62944.1 - 0.07 12.1 0.5 0.23 10.4 0.1 1.9 2 0 0 2 2 2 0 Closterovirus coat protein I-set PF07679.11 EMR62945.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain FTHFS PF01268.14 EMR62946.1 - 6.3e-257 853.0 0.1 8.4e-257 852.6 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EMR62946.1 - 2.3e-69 231.5 0.6 2.3e-69 231.5 0.4 2.3 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EMR62946.1 - 1.7e-37 128.0 0.9 3.4e-37 127.0 0.6 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF2618 PF10940.3 EMR62947.1 - 0.41 10.4 0.1 0.41 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2618) EamA PF00892.15 EMR62948.1 - 1.6e-24 86.3 28.8 1.6e-12 47.5 7.2 2.6 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EMR62948.1 - 0.0071 16.5 27.1 0.083 13.0 4.5 3.0 2 2 1 3 3 3 2 Multidrug resistance efflux transporter WD40 PF00400.27 EMR62949.1 - 3.9e-48 159.6 21.0 9.1e-10 38.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EMR62949.1 - 0.00015 21.4 0.0 0.08 12.6 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A AMP-binding PF00501.23 EMR62950.1 - 2.1e-50 171.3 0.0 2.5e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMR62950.1 - 3.1e-06 28.0 0.1 2.2e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF2436 PF10365.4 EMR62950.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) zf-RanBP PF00641.13 EMR62951.1 - 0.13 11.3 1.8 0.24 10.5 1.2 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Amidase PF01425.16 EMR62952.1 - 2.4e-96 323.2 0.3 3.1e-96 322.9 0.2 1.1 1 0 0 1 1 1 1 Amidase Terpene_synth_C PF03936.11 EMR62953.1 - 2.4e-06 26.9 0.2 0.0062 15.7 0.0 2.6 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain Prenyltrans_1 PF13243.1 EMR62953.1 - 0.00027 20.9 0.1 1.1 9.2 0.0 2.8 2 0 0 2 2 2 2 Prenyltransferase-like Aminotran_1_2 PF00155.16 EMR62954.1 - 7.1e-59 199.5 0.0 1e-58 199.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMR62954.1 - 0.0011 18.2 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase FAD_binding_4 PF01565.18 EMR62955.1 - 9e-25 86.7 1.8 2.1e-24 85.5 1.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR62955.1 - 0.00017 21.4 0.1 0.00046 20.0 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like CRCB PF02537.10 EMR62956.1 - 7.2e-11 42.0 0.3 2.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 CrcB-like protein YEATS PF03366.11 EMR62957.1 - 9.7e-24 82.9 0.1 2.2e-23 81.7 0.1 1.6 1 0 0 1 1 1 1 YEATS family UPRTase PF14681.1 EMR62959.1 - 4.9e-75 251.2 0.0 5.5e-75 251.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EMR62959.1 - 5.7e-06 26.0 0.0 1.9e-05 24.3 0.0 1.8 2 1 0 2 2 2 1 Phosphoribosyl transferase domain TMP-TENI PF02581.12 EMR62959.1 - 0.0094 15.0 0.8 0.23 10.5 0.1 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase/TENI NmrA PF05368.8 EMR62960.1 - 1.2e-30 106.4 0.0 2e-28 99.2 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR62960.1 - 4.1e-11 43.2 0.2 6.6e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EMR62960.1 - 0.00025 20.9 0.2 0.00037 20.3 0.2 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EMR62960.1 - 0.00078 18.5 0.3 0.0011 18.0 0.2 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EMR62960.1 - 0.00087 19.5 0.2 0.0014 18.9 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 EMR62960.1 - 0.0019 18.7 0.1 0.0035 17.8 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase F420_oxidored PF03807.12 EMR62960.1 - 0.0071 16.7 0.2 0.017 15.5 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 EMR62960.1 - 0.084 12.5 0.3 0.17 11.5 0.2 1.5 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 EMR62960.1 - 0.15 10.7 0.1 0.2 10.3 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family YjeF_N PF03853.10 EMR62961.1 - 7.6e-37 126.5 0.0 1.1e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EMR62961.1 - 4.7e-12 46.3 0.3 4.7e-12 46.3 0.2 2.7 3 0 0 3 3 3 1 FDF domain Glyco_hydro_18 PF00704.23 EMR62962.1 - 1.2e-50 172.9 1.0 1.3e-50 172.7 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 A_deaminase PF00962.17 EMR62963.1 - 2.2e-29 102.4 0.0 2.9e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Fungal_trans PF04082.13 EMR62964.1 - 4e-11 42.2 0.4 7.5e-11 41.3 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 EMR62965.1 - 1.2e-11 43.8 0.0 1.4e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AurF PF11583.3 EMR62965.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF Alpha-amylase PF00128.19 EMR62966.1 - 6.3e-94 314.9 0.0 8.4e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EMR62966.1 - 0.00046 19.2 0.0 0.00071 18.5 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme DNA_ligase_A_M PF01068.16 EMR62967.1 - 5.1e-45 153.3 0.0 9.8e-45 152.3 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 EMR62967.1 - 2.1e-16 60.0 0.1 8.4e-16 58.1 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EMR62967.1 - 1.7e-08 34.4 0.0 3.5e-05 23.8 0.0 2.9 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 EMR62967.1 - 0.00024 20.7 0.7 0.00051 19.7 0.0 2.0 2 0 0 2 2 2 1 DNA ligase IV PTCB-BRCT PF12738.2 EMR62967.1 - 0.0088 15.8 1.3 0.32 10.8 0.0 2.9 3 0 0 3 3 3 1 twin BRCT domain mRNA_cap_enzyme PF01331.14 EMR62967.1 - 0.027 14.1 0.1 0.59 9.7 0.1 2.4 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain PIF1 PF05970.9 EMR62968.1 - 2.1e-52 178.2 0.7 1.7e-43 148.9 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EMR62968.1 - 1.8e-17 63.5 0.0 3.7e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMR62968.1 - 6.5e-07 29.5 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMR62968.1 - 7e-06 25.7 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 EMR62968.1 - 2.6e-05 22.2 0.1 0.00016 19.5 0.0 1.9 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 EMR62968.1 - 2.6e-05 24.2 0.2 0.00016 21.7 0.0 2.4 2 1 0 2 2 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 EMR62968.1 - 5.4e-05 22.5 0.0 0.00053 19.2 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 EMR62968.1 - 0.00019 20.4 0.0 0.00032 19.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EMR62968.1 - 0.0002 21.3 0.0 0.00049 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EMR62968.1 - 0.00027 21.1 0.0 0.00057 20.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EMR62968.1 - 0.0023 17.5 2.3 0.016 14.8 0.0 2.8 2 1 1 3 3 2 1 AAA domain ABC_tran PF00005.22 EMR62968.1 - 0.0025 18.1 0.1 0.0086 16.3 0.0 1.9 1 1 1 2 2 2 1 ABC transporter AAA_14 PF13173.1 EMR62968.1 - 0.0033 17.3 0.0 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain TEX33 PF15400.1 EMR62968.1 - 0.008 16.5 0.1 0.019 15.3 0.1 1.6 1 0 0 1 1 1 1 Testis-expressed sequence 33 protein family AAA_33 PF13671.1 EMR62968.1 - 0.009 15.8 0.0 0.094 12.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.21 EMR62968.1 - 0.0096 15.4 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_29 PF13555.1 EMR62968.1 - 0.0098 15.4 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 EMR62968.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 EMR62968.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EMR62968.1 - 0.017 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EMR62968.1 - 0.017 14.5 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Viral_helicase1 PF01443.13 EMR62968.1 - 0.017 14.6 0.0 2.9 7.3 0.0 2.8 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EMR62968.1 - 0.019 14.4 0.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain ResIII PF04851.10 EMR62968.1 - 0.021 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.9 EMR62968.1 - 0.026 14.2 0.1 2.1 8.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.10 EMR62968.1 - 0.027 13.1 0.0 0.045 12.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein NTPase_1 PF03266.10 EMR62968.1 - 0.028 14.1 0.1 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 NTPase MobB PF03205.9 EMR62968.1 - 0.029 14.0 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.4 EMR62968.1 - 0.029 13.3 0.0 0.067 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 EMR62968.1 - 0.031 14.3 0.0 0.065 13.2 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EMR62968.1 - 0.042 13.5 0.0 0.098 12.3 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase Parvo_NS1 PF01057.12 EMR62968.1 - 0.055 12.3 0.0 0.093 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EMR62968.1 - 0.059 12.2 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.16 EMR62968.1 - 0.064 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.2 EMR62968.1 - 0.089 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 DUF815 PF05673.8 EMR62968.1 - 0.095 11.6 0.0 0.21 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SAM_2 PF07647.12 EMR62969.1 - 7.4e-14 51.3 0.0 2.2e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.18 EMR62969.1 - 1.3e-13 51.2 0.0 2.9e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 EMR62969.1 - 2.1e-13 50.2 0.0 3.9e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1993 PF09351.5 EMR62971.1 - 7.5e-43 146.2 0.0 8.6e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) FAD_binding_3 PF01494.14 EMR62972.1 - 7.8e-25 87.6 0.0 5.6e-24 84.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EMR62972.1 - 9.7e-06 24.7 0.1 9.1e-05 21.5 0.0 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EMR62972.1 - 2.8e-05 24.4 0.1 0.0077 16.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR62972.1 - 0.0002 21.2 0.2 0.00053 19.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR62972.1 - 0.0017 18.4 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR62972.1 - 0.0028 17.5 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR62972.1 - 0.0035 15.8 0.2 1.6 7.1 0.0 2.5 3 0 0 3 3 3 2 HI0933-like protein SE PF08491.5 EMR62972.1 - 0.0042 15.9 0.0 0.25 10.1 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase FAD_binding_2 PF00890.19 EMR62972.1 - 0.005 15.7 0.1 0.0075 15.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR62972.1 - 0.0053 15.7 0.2 0.023 13.5 0.1 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EMR62972.1 - 0.0082 15.2 0.0 2.5 7.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 EMR62972.1 - 0.02 14.4 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CH PF00307.26 EMR62972.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Calponin homology (CH) domain GST_N PF02798.15 EMR62973.1 - 4.7e-06 26.6 0.0 8.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR62973.1 - 0.00018 21.4 0.0 0.00031 20.6 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR62973.1 - 0.00037 20.9 0.1 0.00098 19.5 0.1 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMR62973.1 - 0.035 13.9 0.2 0.084 12.7 0.1 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMR62973.1 - 0.083 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GFA PF04828.9 EMR62975.1 - 5.3e-21 74.3 0.0 7.4e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EMR62975.1 - 0.008 15.3 1.1 0.042 13.0 0.1 2.6 3 0 0 3 3 3 1 zinc-ribbon domain DNA_ligase_ZBD PF03119.11 EMR62975.1 - 0.015 14.9 1.0 0.028 14.1 0.2 1.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain NMD3 PF04981.8 EMR62975.1 - 0.071 12.2 0.1 0.51 9.3 0.0 1.9 2 0 0 2 2 2 0 NMD3 family zinc_ribbon_2 PF13240.1 EMR62975.1 - 0.092 12.2 2.3 0.12 11.9 0.1 2.3 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.1 EMR62975.1 - 0.16 11.6 0.0 0.16 11.6 0.0 2.9 3 0 0 3 3 3 0 Nudix N-terminal DZR PF12773.2 EMR62975.1 - 0.17 11.7 3.3 0.41 10.5 1.1 2.3 2 1 1 3 3 3 0 Double zinc ribbon UPF0547 PF10571.4 EMR62975.1 - 3.5 7.3 5.5 2.1 8.1 0.3 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 RNA_POL_M_15KD PF02150.11 EMR62975.1 - 8.1 6.2 6.5 1.3 8.7 0.2 2.6 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Arginase PF00491.16 EMR62976.1 - 3.4e-70 236.4 0.0 6.6e-34 117.4 0.1 2.0 2 0 0 2 2 2 2 Arginase family UPF0489 PF12640.2 EMR62976.1 - 0.064 13.4 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 UPF0489 domain SpoU_methylase PF00588.14 EMR62977.1 - 1.6e-28 99.3 0.0 2.2e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EMR62977.1 - 0.0038 17.3 0.0 0.0072 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.1 EMR62981.1 - 8.6e-65 217.2 9.4 2e-64 216.0 6.5 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EMR62981.1 - 6.6e-55 186.0 0.0 9.5e-55 185.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMR62981.1 - 6.5e-15 54.7 0.0 1.5e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EMR62981.1 - 1.7e-10 40.2 0.4 5.8e-10 38.4 0.3 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EMR62981.1 - 8.3e-05 22.4 0.0 0.00045 20.0 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMR62981.1 - 0.00018 21.0 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.24 EMR62981.1 - 0.0025 17.4 3.1 0.0025 17.4 2.2 4.0 3 2 1 4 4 4 2 PHD-finger Chromo PF00385.19 EMR62981.1 - 0.0039 16.8 1.1 1.2 8.8 0.4 3.5 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain PHD_2 PF13831.1 EMR62981.1 - 0.012 14.8 0.9 0.012 14.8 0.6 3.4 3 0 0 3 3 3 0 PHD-finger HET PF06985.6 EMR62982.1 - 1.2e-23 83.7 6.3 4.8e-21 75.3 4.4 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cytochrom_B561 PF03188.11 EMR62982.1 - 1.1e-10 41.5 10.6 1.1e-10 41.5 7.3 2.0 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EMR62982.1 - 9.6e-07 28.3 2.8 2.8e-06 26.8 1.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Ferric_reduct PF01794.14 EMR62982.1 - 0.11 12.5 7.0 1.1 9.4 3.9 2.9 1 1 0 1 1 1 0 Ferric reductase like transmembrane component Cytochrom_B_N PF00033.14 EMR62982.1 - 0.25 10.6 13.4 1.5 8.1 9.4 2.1 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB AAA PF00004.24 EMR62983.1 - 2e-18 66.8 0.0 4.1e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMR62983.1 - 4.5e-05 24.2 0.0 0.00017 22.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMR62983.1 - 0.00083 19.6 0.1 0.0049 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMR62983.1 - 0.0012 19.0 0.0 0.0097 16.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EMR62983.1 - 0.0013 17.8 0.0 0.0032 16.5 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EMR62983.1 - 0.0015 18.5 0.4 0.0049 16.8 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EMR62983.1 - 0.013 15.1 0.1 0.1 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMR62983.1 - 0.014 15.2 0.0 0.48 10.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EMR62983.1 - 0.024 14.3 0.4 0.065 12.9 0.3 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EMR62983.1 - 0.096 12.5 0.0 0.22 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain FMN_dh PF01070.13 EMR62984.1 - 1.7e-113 379.1 0.0 1.9e-113 378.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EMR62984.1 - 2.3e-06 26.7 0.4 4e-06 25.9 0.3 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EMR62984.1 - 0.0012 17.7 0.1 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EMR62984.1 - 0.0033 16.7 0.1 0.012 14.8 0.0 1.9 1 1 1 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.16 EMR62984.1 - 0.039 12.8 0.2 0.096 11.6 0.1 1.6 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase ThiG PF05690.9 EMR62984.1 - 0.092 11.8 0.2 0.27 10.2 0.2 1.8 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG NMO PF03060.10 EMR62984.1 - 0.17 11.0 1.2 0.26 10.4 0.8 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase AA_permease PF00324.16 EMR62985.1 - 8.9e-107 357.3 40.9 1.1e-106 357.0 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR62985.1 - 2.7e-25 88.7 44.7 3.5e-25 88.4 31.0 1.1 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.17 EMR62986.1 - 4.3e-42 144.0 1.4 1.2e-27 96.3 0.0 4.0 1 1 2 3 3 3 3 Aldehyde dehydrogenase family PEPCK_ATP PF01293.15 EMR62987.1 - 4.4e-216 717.8 0.0 5.3e-216 717.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 EMR62987.1 - 0.034 13.6 0.0 0.088 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EMR62987.1 - 0.037 14.3 0.1 11 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EMR62987.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMR62987.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Abhydrolase_6 PF12697.2 EMR62988.1 - 1e-16 61.5 1.5 3.5e-16 59.7 1.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR62988.1 - 3.4e-07 30.1 0.0 5.9e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR62988.1 - 0.029 13.9 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ribosomal_S17 PF00366.15 EMR62989.1 - 7.3e-30 102.8 0.4 1.2e-29 102.1 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 RGCC PF15151.1 EMR62990.1 - 0.00086 19.7 0.9 0.0038 17.6 0.1 1.9 1 1 1 2 2 2 1 Response gene to complement 32 protein family MAP7 PF05672.6 EMR62990.1 - 0.0043 16.4 5.0 0.007 15.7 3.5 1.3 1 1 0 1 1 1 1 MAP7 (E-MAP-115) family PPK2 PF03976.9 EMR62990.1 - 0.04 13.2 0.8 0.055 12.7 0.6 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) NAD_binding_10 PF13460.1 EMR62990.1 - 0.046 13.7 0.1 0.087 12.8 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding APG6 PF04111.7 EMR62991.1 - 6.2e-117 390.1 0.0 7.2e-117 389.9 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 Spc24 PF08286.6 EMR62991.1 - 0.013 15.1 1.7 0.39 10.4 3.3 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 IncA PF04156.9 EMR62991.1 - 0.06 12.9 11.4 0.089 12.3 7.9 1.2 1 0 0 1 1 1 0 IncA protein DUF3584 PF12128.3 EMR62991.1 - 0.079 10.2 10.8 0.099 9.9 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-C4H2 PF10146.4 EMR62991.1 - 0.086 12.8 11.2 0.32 10.9 7.8 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein DUF972 PF06156.8 EMR62991.1 - 0.097 13.0 4.9 0.094 13.0 2.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EMR62991.1 - 0.12 12.2 8.4 0.35 10.7 5.8 1.8 1 0 0 1 1 1 0 Basic region leucine zipper DUF904 PF06005.7 EMR62991.1 - 0.15 12.4 7.9 0.34 11.2 5.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) AAA_26 PF13500.1 EMR62991.1 - 0.25 10.9 0.6 0.39 10.2 0.4 1.5 1 1 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EMR62991.1 - 0.28 8.9 6.0 0.39 8.5 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EMR62991.1 - 0.42 8.9 2.9 0.63 8.4 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MIS13 PF08202.6 EMR62991.1 - 0.5 9.3 10.3 0.6 9.1 6.8 1.3 1 1 0 1 1 1 0 Mis12-Mtw1 protein family FUSC PF04632.7 EMR62991.1 - 0.91 7.8 4.6 1.6 7.0 3.2 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4140 PF13600.1 EMR62991.1 - 1.6 9.2 11.4 15 6.1 6.4 3.1 1 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4337 PF14235.1 EMR62991.1 - 7.5 6.3 10.7 14 5.4 7.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Atg14 PF10186.4 EMR62992.1 - 2.7e-41 141.5 0.0 3.1e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 FAD_binding_4 PF01565.18 EMR62993.1 - 2.4e-11 43.2 0.0 5.9e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR62993.1 - 0.06 13.2 2.2 0.13 12.1 0.3 2.3 2 0 0 2 2 2 0 Berberine and berberine like CHCH PF06747.8 EMR62994.1 - 1.1 9.2 4.4 1.8 8.5 0.6 2.3 2 0 0 2 2 2 0 CHCH domain adh_short PF00106.20 EMR62995.1 - 1.5e-18 67.3 0.2 9.3e-17 61.4 0.2 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR62995.1 - 7.2e-06 25.9 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR62995.1 - 0.00079 19.1 0.1 0.0095 15.6 0.0 2.3 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMR62995.1 - 0.0024 17.8 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR62995.1 - 0.0069 15.8 0.0 0.25 10.7 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMR62995.1 - 0.015 15.0 0.1 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 EMR62995.1 - 0.034 13.5 0.2 0.17 11.2 0.1 2.0 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA YjeF_N PF03853.10 EMR62995.1 - 0.046 13.3 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.13 EMR62995.1 - 0.097 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMR62995.1 - 0.11 12.2 0.1 7.8 6.2 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Vps8 PF12816.2 EMR62996.1 - 1.6e-76 255.9 0.0 3.2e-75 251.6 0.0 2.5 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EMR62996.1 - 4e-08 32.9 0.2 0.0025 17.4 0.0 3.3 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EMR62996.1 - 0.086 12.6 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EMR62996.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMR62996.1 - 0.26 11.3 0.0 0.8 9.7 0.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNase_H PF00075.19 EMR62997.1 - 3e-16 59.9 0.0 7.4e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 RNase H Glyco_hydro_2_N PF02837.13 EMR62998.1 - 1.2e-36 125.8 0.0 3.4e-36 124.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EMR62998.1 - 3.5e-28 98.3 0.0 1e-27 96.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EMR62998.1 - 4.6e-16 59.2 0.3 9.8e-16 58.1 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EMR62998.1 - 0.00018 21.7 0.1 0.061 13.5 0.0 3.6 4 0 0 4 4 4 1 Beta-galactosidase jelly roll domain COPR5 PF15340.1 EMR62998.1 - 0.013 15.8 0.1 0.028 14.7 0.1 1.5 1 0 0 1 1 1 0 Cooperator of PRMT5 family DUF3752 PF12572.3 EMR62999.1 - 2.4e-36 125.1 11.6 2.4e-36 125.1 8.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3752) Caps_synth PF05704.7 EMR63001.1 - 3e-08 33.1 0.0 5.9e-08 32.2 0.0 1.4 2 0 0 2 2 2 1 Capsular polysaccharide synthesis protein DUF3807 PF12720.2 EMR63002.1 - 6.5e-41 140.3 12.0 8.6e-41 139.9 8.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) GAGA_bind PF06217.7 EMR63002.1 - 0.024 14.6 4.8 0.033 14.1 3.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SRP-alpha_N PF04086.8 EMR63002.1 - 0.26 10.6 11.6 0.36 10.1 8.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pkinase PF00069.20 EMR63003.1 - 8.8e-61 205.3 0.0 1e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR63003.1 - 5.8e-19 68.1 0.0 8.5e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMR63003.1 - 3.2e-08 33.5 0.0 9.6e-06 25.4 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMR63003.1 - 0.0077 15.8 0.2 0.027 14.0 0.1 1.9 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EMR63003.1 - 0.019 13.9 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EMR63003.1 - 0.045 12.8 0.2 0.087 11.8 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMR63003.1 - 0.088 12.1 0.3 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Oxidored_FMN PF00724.15 EMR63005.1 - 1.4e-66 224.8 0.0 1.7e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PcrB PF01884.12 EMR63005.1 - 0.055 12.7 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 PcrB family ACT PF01842.20 EMR63005.1 - 0.12 11.9 0.0 0.6 9.6 0.0 2.2 2 0 0 2 2 2 0 ACT domain Dus PF01207.12 EMR63005.1 - 0.19 10.5 0.0 0.88 8.3 0.0 1.8 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Spc7_N PF15402.1 EMR63007.1 - 7.8e-218 725.7 58.5 1.2e-129 433.9 28.9 2.3 1 1 1 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EMR63007.1 - 7.8e-118 392.8 6.9 7.8e-118 392.8 4.8 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 EMR63007.1 - 2.5e-15 55.8 0.6 8e-15 54.2 0.4 1.9 1 0 0 1 1 1 1 Spc7_C2 APT PF03440.9 EMR63007.1 - 0.1 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain TPR_MLP1_2 PF07926.7 EMR63007.1 - 3.1 7.5 18.9 0.059 13.1 5.2 3.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Mnd1 PF03962.10 EMR63007.1 - 3.2 7.3 25.3 0.18 11.4 3.8 4.0 3 1 1 4 4 4 0 Mnd1 family Seryl_tRNA_N PF02403.17 EMR63007.1 - 8.2 6.4 16.7 0.12 12.3 5.1 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ICL PF00463.16 EMR63009.1 - 3.9e-195 649.0 0.0 4.4e-195 648.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family adh_short PF00106.20 EMR63010.1 - 6.2e-27 94.5 2.7 8.4e-27 94.1 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR63010.1 - 5.1e-14 52.6 0.1 6.3e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR63010.1 - 4.7e-10 39.4 1.6 7.4e-10 38.7 1.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMR63010.1 - 0.00016 20.7 0.5 0.00023 20.1 0.1 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EMR63010.1 - 0.00017 21.3 0.2 0.00036 20.2 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EMR63010.1 - 0.0049 16.3 0.1 0.0075 15.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR63010.1 - 0.015 14.0 0.3 0.073 11.7 0.1 2.0 1 1 2 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_N PF03721.9 EMR63010.1 - 0.04 13.3 0.1 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 EMR63010.1 - 0.054 14.0 0.1 0.15 12.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EMR63010.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 EMR63010.1 - 0.4 10.5 2.9 0.56 10.0 0.9 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SIN1 PF05422.7 EMR63011.1 - 1.1e-37 129.7 0.8 9.5e-20 70.5 0.0 3.1 3 0 0 3 3 3 3 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EMR63011.1 - 0.0026 17.6 0.1 0.0057 16.5 0.1 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG DctQ PF04290.7 EMR63012.1 - 1.3 8.7 9.3 1.7 8.3 5.5 1.9 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Pkinase PF00069.20 EMR63013.1 - 2.2e-07 30.3 0.5 0.0017 17.5 0.1 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR63013.1 - 6.1e-05 22.2 0.0 0.04 12.9 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EMR63013.1 - 0.0035 17.0 3.6 0.0098 15.6 0.1 2.9 2 2 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMR63013.1 - 0.01 14.9 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase SET PF00856.23 EMR63015.1 - 2.5e-10 40.9 0.0 4.3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 SET domain Abhydrolase_6 PF12697.2 EMR63016.1 - 2.2e-06 27.7 0.0 2.4e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3077 PF11275.3 EMR63016.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3077) Ank_2 PF12796.2 EMR63017.1 - 2.4e-94 309.8 21.9 4.4e-17 62.1 0.3 9.1 3 2 4 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 EMR63017.1 - 4.8e-70 228.0 51.6 5.1e-07 29.1 0.1 19.6 20 0 0 20 20 20 14 Ankyrin repeat Ank_4 PF13637.1 EMR63017.1 - 1.3e-61 203.9 18.6 4.1e-10 39.8 0.0 14.1 8 4 7 15 15 15 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR63017.1 - 7.2e-51 169.0 34.5 2.3e-05 24.4 0.1 15.5 7 4 10 17 17 17 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR63017.1 - 1.5e-48 157.9 28.9 9.7e-05 22.2 0.0 18.4 19 0 0 19 19 19 11 Ankyrin repeat Abhydrolase_6 PF12697.2 EMR63017.1 - 6.8e-06 26.1 0.2 3.5e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_22 PF13401.1 EMR63017.1 - 2.7e-05 24.2 0.0 0.00018 21.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain PGAP1 PF07819.8 EMR63017.1 - 0.0056 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EMR63017.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) 4HBT_3 PF13622.1 EMR63018.1 - 9.8e-13 48.4 0.1 1.3e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMR63018.1 - 0.00011 21.8 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA thioesterase Glyco_hydro_20 PF00728.17 EMR63020.1 - 1e-87 294.6 0.0 1.3e-87 294.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EMR63020.1 - 1.1e-21 77.8 0.2 2.1e-21 76.9 0.1 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EMR63020.1 - 4.6e-05 23.9 0.1 0.00024 21.6 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Aldedh PF00171.17 EMR63021.1 - 4.5e-183 608.8 0.0 5.1e-183 608.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ACOX PF01756.14 EMR63022.1 - 4.8e-34 117.3 0.1 1e-33 116.2 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EMR63022.1 - 4.8e-15 55.9 0.0 9.6e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EMR63022.1 - 8.1e-06 25.2 0.1 4.4e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EMR63022.1 - 0.00061 19.9 3.4 0.0059 16.7 2.4 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_hydro_61 PF03443.9 EMR63023.1 - 4.5e-66 222.7 0.1 5.2e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cerato-platanin PF07249.7 EMR63024.1 - 3.6e-09 36.6 2.2 4.5e-08 33.0 0.1 2.1 2 0 0 2 2 2 2 Cerato-platanin BHD_3 PF10405.4 EMR63025.1 - 3e-24 84.5 0.0 4.8e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EMR63025.1 - 4.1e-22 77.4 0.0 8.7e-22 76.4 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EMR63025.1 - 2.7e-12 46.8 0.0 7.4e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.10 EMR63025.1 - 0.033 13.5 0.1 0.071 12.5 0.0 1.6 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain Caps_synth_GfcC PF06251.6 EMR63025.1 - 0.13 11.4 0.3 0.19 10.8 0.2 1.1 1 0 0 1 1 1 0 Capsule biosynthesis GfcC ProSAAS PF07259.7 EMR63025.1 - 0.42 10.1 2.5 1.1 8.7 0.9 2.1 2 0 0 2 2 2 0 ProSAAS precursor VHS PF00790.14 EMR63026.1 - 1.6e-23 82.9 0.0 3.1e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EMR63026.1 - 7.8e-11 41.8 0.6 1.8e-10 40.6 0.4 1.6 1 0 0 1 1 1 1 GAT domain Abhydrolase_3 PF07859.8 EMR63027.1 - 5e-20 71.9 0.1 7.3e-20 71.4 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tyrosinase PF00264.15 EMR63028.1 - 2.8e-26 93.0 0.3 4.3e-26 92.4 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Abhydrolase_3 PF07859.8 EMR63029.1 - 0.001 18.7 0.0 0.0026 17.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DHDPS PF00701.17 EMR63030.1 - 2.8e-37 127.9 0.0 3.9e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family IU_nuc_hydro PF01156.14 EMR63030.1 - 0.072 12.2 0.1 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 Inosine-uridine preferring nucleoside hydrolase ABC_tran PF00005.22 EMR63032.1 - 1.9e-46 157.7 0.2 9.3e-25 87.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMR63032.1 - 5e-22 79.2 5.1 6.9e-06 26.2 0.0 4.4 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 EMR63032.1 - 1.7e-09 37.0 2.2 0.00042 19.7 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EMR63032.1 - 9.9e-08 31.4 0.7 0.23 10.6 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMR63032.1 - 6.6e-06 26.5 3.2 0.051 13.9 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMR63032.1 - 0.00011 22.3 0.5 0.61 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EMR63032.1 - 0.00044 19.4 0.9 0.25 10.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EMR63032.1 - 0.0068 15.8 0.1 1.2 8.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EMR63032.1 - 0.01 14.9 0.0 8.1 5.3 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.1 EMR63032.1 - 0.013 15.1 0.3 5.1 6.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EMR63032.1 - 0.027 13.8 0.5 5.9 6.2 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EMR63032.1 - 0.048 13.8 0.1 10 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain MutS_V PF00488.16 EMR63032.1 - 0.067 12.5 0.1 14 5.0 0.0 2.5 2 0 0 2 2 2 0 MutS domain V AAA_10 PF12846.2 EMR63032.1 - 0.072 12.5 0.5 8.1 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_13 PF13166.1 EMR63032.1 - 0.077 11.4 0.1 1.4 7.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EMR63032.1 - 0.08 12.0 0.4 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 EMR63032.1 - 0.086 12.7 0.1 11 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EMR63032.1 - 0.15 12.2 0.0 31 4.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 EMR63032.1 - 0.27 11.0 5.1 15 5.3 0.0 3.4 3 0 0 3 3 3 0 Part of AAA domain Mg_chelatase PF01078.16 EMR63032.1 - 0.28 10.3 1.2 28 3.7 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.12 EMR63032.1 - 0.35 10.6 1.4 23 4.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_28 PF13521.1 EMR63032.1 - 0.45 10.4 1.2 31 4.4 0.5 2.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EMR63032.1 - 0.68 8.5 0.2 5.8 5.5 0.2 2.0 2 0 0 2 2 2 0 G-protein alpha subunit FAD_binding_4 PF01565.18 EMR63033.1 - 5.7e-17 61.4 0.0 1.2e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Amidase PF01425.16 EMR63034.1 - 6.8e-80 269.0 0.2 9.3e-80 268.6 0.2 1.2 1 0 0 1 1 1 1 Amidase INCENP_ARK-bind PF03941.10 EMR63035.1 - 1.1e-16 60.4 0.3 1.1e-16 60.4 0.2 2.8 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region UPF0147 PF03685.8 EMR63035.1 - 0.019 14.8 0.6 0.019 14.8 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) PTS_2-RNA PF01885.11 EMR63036.1 - 3.2e-59 199.3 0.0 4e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 EMR63036.1 - 0.047 13.5 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 La domain Transferase PF02458.10 EMR63037.1 - 2.4e-15 55.9 0.0 5.6e-13 48.1 0.0 2.0 2 0 0 2 2 2 2 Transferase family Mob1_phocein PF03637.12 EMR63038.1 - 2.6e-53 180.2 0.0 3e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Mito_carr PF00153.22 EMR63039.1 - 3.9e-17 61.7 3.2 2.1e-16 59.3 0.2 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Fungal_trans PF04082.13 EMR63041.1 - 2.5e-30 105.2 0.0 4.2e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tautomerase_3 PF14832.1 EMR63042.1 - 3.1e-21 75.8 0.1 3.3e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 EMR63042.1 - 0.076 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Tautomerase enzyme ADH_zinc_N PF00107.21 EMR63043.1 - 1.9e-12 46.8 0.2 3.2e-12 46.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR63043.1 - 6.2e-08 33.5 0.3 1.1e-07 32.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR63043.1 - 3.1e-07 30.1 0.0 6.6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.3 EMR63043.1 - 0.026 13.6 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) PigN PF04987.9 EMR63044.1 - 7.3e-116 387.4 35.1 1.1e-81 274.7 11.2 3.4 2 1 1 3 3 3 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EMR63044.1 - 4.5e-10 39.3 1.5 1.5e-08 34.3 0.2 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMR63044.1 - 8.1e-08 31.8 0.4 1.3e-07 31.1 0.3 1.3 1 0 0 1 1 1 1 Sulfatase Peptidase_S8 PF00082.17 EMR63045.1 - 5.7e-58 196.2 0.0 4.2e-56 190.1 0.0 2.4 2 1 0 2 2 2 1 Subtilase family DUF1034 PF06280.7 EMR63045.1 - 4.1e-15 56.1 0.1 7.8e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) FixG_C PF11614.3 EMR63045.1 - 0.0031 17.5 0.0 0.0076 16.3 0.0 1.6 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF916 PF06030.7 EMR63045.1 - 0.071 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) TPR_2 PF07719.12 EMR63047.1 - 0.21 11.5 0.9 10 6.3 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Hemerythrin PF01814.18 EMR63048.1 - 2.6e-11 43.7 1.7 4.6e-11 42.9 1.1 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TauE PF01925.14 EMR63049.1 - 0.0049 16.3 0.7 0.0066 15.9 0.5 1.2 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE VSP PF03302.8 EMR63049.1 - 0.013 14.1 4.8 0.017 13.7 3.3 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein SCF PF02404.10 EMR63049.1 - 0.23 10.5 4.8 0.34 10.0 3.3 1.1 1 0 0 1 1 1 0 Stem cell factor DUF822 PF05687.8 EMR63049.1 - 5.5 7.3 7.8 8.8 6.6 5.4 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Vps26 PF03643.10 EMR63051.1 - 3e-21 75.4 0.0 3.4e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 DUF432 PF04254.8 EMR63051.1 - 0.011 15.6 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF432) Arrestin_N PF00339.24 EMR63051.1 - 0.028 14.2 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Ribosomal_L6 PF00347.18 EMR63052.1 - 4.7e-26 91.0 8.7 1.3e-13 51.2 1.8 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 TRI12 PF06609.8 EMR63053.1 - 2.5e-21 75.5 9.6 3e-21 75.2 6.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EMR63053.1 - 5.9e-08 31.8 12.8 5.9e-08 31.8 8.9 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily MNSV_P7B PF06692.6 EMR63053.1 - 0.037 13.8 0.4 0.17 11.7 0.1 2.1 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein FPN1 PF06963.7 EMR63053.1 - 0.3 9.4 7.8 0.036 12.4 0.7 2.1 1 1 1 2 2 2 0 Ferroportin1 (FPN1) adh_short PF00106.20 EMR63057.1 - 1.2e-28 100.1 1.5 2e-28 99.4 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR63057.1 - 3.8e-23 82.4 0.1 5e-23 82.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR63057.1 - 3.2e-18 66.0 1.2 4.3e-18 65.6 0.3 1.5 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 EMR63057.1 - 0.02 13.6 0.0 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family YjeF_N PF03853.10 EMR63057.1 - 0.022 14.3 0.1 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Epimerase PF01370.16 EMR63057.1 - 0.024 14.0 0.1 0.036 13.4 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMR63057.1 - 0.065 12.1 0.6 0.1 11.4 0.4 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain SRP14 PF02290.10 EMR63059.1 - 2.4e-25 88.2 0.0 3.3e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein MIF4G PF02854.14 EMR63060.1 - 1e-16 60.9 0.0 1.7e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EMR63060.1 - 0.00028 20.5 0.1 0.001 18.7 0.0 2.0 3 0 0 3 3 3 1 MA3 domain RRM_1 PF00076.17 EMR63061.1 - 1.1e-43 146.7 0.0 4.5e-18 64.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR63061.1 - 1.9e-34 117.4 0.0 5.3e-14 51.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR63061.1 - 7.9e-21 73.6 0.0 2e-06 27.5 0.0 3.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMR63061.1 - 0.0001 22.0 0.0 1.5 8.6 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 EMR63061.1 - 0.0086 15.8 0.0 1.2 8.9 0.0 3.1 3 1 0 3 3 3 1 Limkain b1 ATP-grasp_2 PF08442.5 EMR63061.1 - 0.012 14.9 0.1 1.4 8.2 0.0 3.5 4 0 0 4 4 4 0 ATP-grasp domain MFS_1 PF07690.11 EMR63062.1 - 1.1e-18 67.0 55.2 7.4e-10 38.0 19.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily KR PF08659.5 EMR63063.1 - 2.5e-38 131.5 0.1 5.8e-38 130.3 0.1 1.7 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EMR63063.1 - 1.9e-30 105.9 0.3 6e-30 104.3 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase ketoacyl-synt PF00109.21 EMR63063.1 - 7.3e-24 84.6 2.1 9.2e-17 61.3 0.0 4.1 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ADH_zinc_N PF00107.21 EMR63063.1 - 1.9e-15 56.5 0.0 4.7e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ketoacyl-synt_C PF02801.17 EMR63063.1 - 4.3e-13 49.1 0.0 1.1e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_N PF08240.7 EMR63063.1 - 1.2e-06 28.2 0.3 2.9e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AAA_29 PF13555.1 EMR63064.1 - 0.17 11.4 0.3 16 5.0 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain SMP PF04927.7 EMR63065.1 - 1.8e-06 27.7 3.1 2.8e-06 27.2 2.2 1.3 1 0 0 1 1 1 1 Seed maturation protein UPF0278 PF08745.6 EMR63066.1 - 0.018 14.2 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 UPF0278 family LysM PF01476.15 EMR63069.1 - 5.8e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 LysM domain Epimerase PF01370.16 EMR63070.1 - 6.2e-11 42.1 0.0 8.5e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR63070.1 - 3e-05 23.0 1.1 8.4e-05 21.6 0.1 1.8 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EMR63070.1 - 0.006 16.5 0.3 0.064 13.1 0.1 2.2 1 1 1 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMR63070.1 - 0.039 13.9 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding tRNA-synt_2b PF00587.20 EMR63071.1 - 2.9e-21 75.7 0.0 5.9e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 EMR63071.1 - 4.7e-21 74.4 0.1 1.1e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EMR63071.1 - 1e-16 60.5 0.0 2.4e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain ABC_membrane PF00664.18 EMR63072.1 - 2.9e-68 230.2 25.5 3e-40 138.3 0.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMR63072.1 - 6.8e-66 220.7 0.0 2.7e-32 111.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMR63072.1 - 2.6e-13 49.7 5.2 0.0002 20.6 0.0 4.4 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMR63072.1 - 5.5e-10 38.6 0.9 0.0013 18.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EMR63072.1 - 1.1e-09 38.7 0.1 0.62 9.9 0.0 4.2 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 EMR63072.1 - 2.6e-07 31.4 0.0 0.0041 17.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMR63072.1 - 2.4e-06 26.8 0.0 0.054 12.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 EMR63072.1 - 2.7e-06 27.3 0.7 0.00076 19.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_25 PF13481.1 EMR63072.1 - 6.3e-06 25.7 3.1 0.047 13.0 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.1 EMR63072.1 - 1.4e-05 24.8 0.6 0.04 13.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EMR63072.1 - 3.1e-05 24.1 0.1 0.28 11.3 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EMR63072.1 - 6.7e-05 23.2 0.0 0.08 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMR63072.1 - 0.00013 21.1 0.1 0.081 12.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_23 PF13476.1 EMR63072.1 - 0.00015 22.1 0.0 0.11 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMR63072.1 - 0.00022 20.9 0.0 1.2 8.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EMR63072.1 - 0.00029 20.3 1.2 0.48 9.8 0.1 3.3 3 0 0 3 3 3 1 AAA-like domain G-alpha PF00503.15 EMR63072.1 - 0.00033 19.4 0.0 0.6 8.7 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit SbcCD_C PF13558.1 EMR63072.1 - 0.00037 20.3 1.7 2.7 7.9 0.1 4.0 3 1 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 EMR63072.1 - 0.0024 17.8 7.3 0.089 12.7 0.8 3.0 2 2 0 2 2 2 1 AAA ATPase domain PRK PF00485.13 EMR63072.1 - 0.0028 17.2 0.3 2.9 7.4 0.0 2.6 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.16 EMR63072.1 - 0.0054 15.9 0.0 2.6 7.1 0.0 3.0 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EMR63072.1 - 0.012 15.5 0.5 5.5 6.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.15 EMR63072.1 - 0.013 15.1 0.2 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 EMR63072.1 - 0.021 14.7 0.9 12 5.8 0.1 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF927 PF06048.6 EMR63072.1 - 0.022 14.0 0.1 0.46 9.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF927) AAA_19 PF13245.1 EMR63072.1 - 0.023 14.4 2.6 2.3 8.0 0.0 3.3 3 0 0 3 3 2 0 Part of AAA domain MobB PF03205.9 EMR63072.1 - 0.043 13.5 0.1 3 7.5 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EMR63072.1 - 0.045 12.6 0.4 3.6 6.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain SRP54 PF00448.17 EMR63072.1 - 0.047 13.1 0.2 5.6 6.3 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF3987 PF13148.1 EMR63072.1 - 0.072 11.6 1.4 0.98 7.9 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3987) AAA_14 PF13173.1 EMR63072.1 - 0.12 12.2 0.0 28 4.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EMR63072.1 - 0.15 12.2 0.1 29 4.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.1 EMR63072.1 - 0.78 8.7 0.0 30 3.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain GMC_oxred_N PF00732.14 EMR63073.1 - 2.8e-30 105.5 0.0 2.5e-28 99.0 0.0 2.7 1 1 1 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR63073.1 - 6.7e-30 104.2 0.0 1e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMR63073.1 - 0.00069 18.5 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMR63073.1 - 0.0051 15.3 0.0 0.0082 14.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EMR63073.1 - 0.0084 16.0 0.0 0.029 14.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR63073.1 - 0.015 15.4 0.0 1.2 9.0 0.0 3.1 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR63073.1 - 0.022 14.7 0.1 0.1 12.6 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR63073.1 - 0.025 13.4 0.0 0.072 11.9 0.0 1.8 1 0 0 1 1 1 0 FAD dependent oxidoreductase NADHdh_A3 PF14987.1 EMR63073.1 - 0.095 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Lycopene_cycl PF05834.7 EMR63073.1 - 0.11 11.3 0.1 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NPP1 PF05630.6 EMR63075.1 - 1.4e-36 126.1 0.1 1.8e-21 76.8 0.0 2.1 1 1 1 2 2 2 2 Necrosis inducing protein (NPP1) HET PF06985.6 EMR63076.1 - 4.8e-14 52.6 0.0 1e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APC_CDC26 PF10471.4 EMR63077.1 - 0.27 11.9 0.0 0.27 11.9 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 MARVEL PF01284.18 EMR63078.1 - 0.00018 21.3 9.9 0.00026 20.8 6.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3671 PF12420.3 EMR63078.1 - 0.066 13.1 1.4 0.22 11.5 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function ArsA_ATPase PF02374.10 EMR63078.1 - 0.15 11.1 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase CbiQ PF02361.11 EMR63078.1 - 1.7 8.1 13.2 2.7 7.4 9.1 1.3 1 1 0 1 1 1 0 Cobalt transport protein DUF4131 PF13567.1 EMR63078.1 - 1.8 7.9 12.7 2.2 7.6 4.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3366 PF11846.3 EMR63078.1 - 4.6 7.0 8.1 2.6 7.8 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) SET PF00856.23 EMR63080.1 - 0.0011 19.2 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 SET domain MMR_HSR1_C PF08438.5 EMR63081.1 - 3.2e-30 104.5 0.0 5.5e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EMR63081.1 - 3.5e-19 68.8 0.0 6.7e-19 67.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMR63081.1 - 6.1e-09 35.3 0.1 1.4e-07 30.9 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EMR63081.1 - 0.00036 20.0 0.3 0.32 10.4 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EMR63081.1 - 0.01 16.1 0.0 0.38 11.0 0.0 2.6 2 1 0 2 2 2 0 ABC transporter ArgK PF03308.11 EMR63081.1 - 0.012 14.3 0.1 0.11 11.2 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 EMR63081.1 - 0.014 15.2 0.2 0.14 11.9 0.1 2.4 3 0 0 3 3 3 0 Dynamin family AAA_30 PF13604.1 EMR63081.1 - 0.041 13.4 0.0 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain VirB8 PF04335.8 EMR63081.1 - 0.099 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 VirB8 protein ATP_bind_1 PF03029.12 EMR63081.1 - 0.12 11.8 0.1 12 5.3 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein KTI12 PF08433.5 EMR63081.1 - 0.17 11.0 0.0 0.87 8.7 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Glyco_tran_28_C PF04101.11 EMR63082.1 - 1.8e-15 56.9 0.1 2.5e-10 40.2 0.0 2.7 2 1 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain SUZ PF12752.2 EMR63082.1 - 4.4 7.9 7.3 2.5 8.6 1.1 2.3 2 0 0 2 2 2 0 SUZ domain MRP-S28 PF10213.4 EMR63084.1 - 3.5e-47 159.6 1.7 7.7e-47 158.5 0.1 2.2 3 0 0 3 3 3 1 Mitochondrial ribosomal subunit protein Ribosomal_L18e PF00828.14 EMR63086.1 - 1.7e-24 86.5 0.0 1.7e-24 86.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Aldo_ket_red PF00248.16 EMR63087.1 - 1.6e-68 230.5 0.0 1.9e-68 230.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UTP15_C PF09384.5 EMR63088.1 - 4.4e-43 146.5 0.0 7.5e-43 145.7 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EMR63088.1 - 1.7e-27 94.2 1.5 2.2e-07 30.4 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EMR63088.1 - 0.061 11.6 0.1 6.6 4.9 0.0 2.4 2 0 0 2 2 2 0 Cytochrome D1 heme domain RRM_5 PF13893.1 EMR63089.1 - 3.5e-05 23.5 0.0 5.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR63089.1 - 5e-05 22.8 0.1 0.00017 21.1 0.1 1.7 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR63089.1 - 0.034 14.1 0.1 0.14 12.1 0.1 1.9 1 1 1 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EMR63089.1 - 5 5.4 12.5 6.3 5.1 8.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mito_carr PF00153.22 EMR63090.1 - 9.7e-74 243.1 4.4 1.4e-24 85.5 0.0 3.7 3 1 1 4 4 4 3 Mitochondrial carrier protein Oxidored_FMN PF00724.15 EMR63091.1 - 1.5e-78 264.1 0.0 1.7e-78 264.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 EMR63091.1 - 0.023 13.9 0.0 2.5 7.3 0.0 3.0 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel Fungal_trans PF04082.13 EMR63092.1 - 1.3e-33 115.9 0.8 2.7e-33 114.9 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR63092.1 - 2.1e-08 33.9 14.4 4.2e-08 32.9 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 EMR63092.1 - 0.15 10.3 0.2 0.23 9.6 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein ECH PF00378.15 EMR63093.1 - 2.1e-38 131.8 0.1 6.6e-38 130.2 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EMR63093.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region p25-alpha PF05517.7 EMR63093.1 - 0.057 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 p25-alpha ADH_N PF08240.7 EMR63094.1 - 2.9e-10 39.8 0.3 6.9e-10 38.6 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR63094.1 - 1.6e-06 27.6 0.1 3.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.20 EMR63095.1 - 9.5e-13 47.8 0.0 1.7e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EMR63095.1 - 0.0038 16.9 0.0 0.013 15.2 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EMR63095.1 - 0.024 13.6 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Syndecan PF01034.15 EMR63096.1 - 0.34 10.5 1.6 0.65 9.6 1.1 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 EMR63096.1 - 0.51 9.6 4.2 0.93 8.8 2.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF159 PF02586.9 EMR63097.1 - 6.7e-58 195.6 0.0 1.5e-57 194.4 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised ACR, COG2135 DUF4551 PF15087.1 EMR63097.1 - 9.9 4.3 6.3 15 3.7 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-CCHC PF00098.18 EMR63098.1 - 3.5e-57 187.7 100.3 8.9e-07 28.5 2.4 11.3 11 0 0 11 11 11 11 Zinc knuckle zf-CCHC_4 PF14392.1 EMR63098.1 - 2.3e-05 23.9 80.0 0.4 10.3 2.1 11.2 11 0 0 11 11 11 10 Zinc knuckle zf-CCHC_3 PF13917.1 EMR63098.1 - 6.9e-05 22.4 80.9 0.0039 16.8 1.2 10.8 3 3 7 10 10 10 9 Zinc knuckle zf-CCHC_2 PF13696.1 EMR63098.1 - 0.019 14.4 1.1 0.019 14.4 0.7 9.4 6 3 6 12 12 12 0 Zinc knuckle zf-CCHC_6 PF15288.1 EMR63098.1 - 0.069 12.8 0.2 0.069 12.8 0.2 11.2 7 4 4 11 11 11 0 Zinc knuckle WD40 PF00400.27 EMR63099.1 - 1.1e-43 145.6 26.8 1.9e-08 33.8 0.1 10.1 11 0 0 11 11 11 7 WD domain, G-beta repeat DUF3639 PF12341.3 EMR63099.1 - 0.084 12.8 0.1 0.084 12.8 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3639) IKI3 PF04762.7 EMR63099.1 - 0.24 9.1 0.0 4.5 4.9 0.0 2.1 2 0 0 2 2 2 0 IKI3 family Ank_2 PF12796.2 EMR63100.1 - 6.6e-46 154.5 3.0 2.7e-10 40.4 0.1 7.2 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMR63100.1 - 4.1e-36 119.3 2.5 0.0034 17.4 0.0 9.9 10 0 0 10 10 10 8 Ankyrin repeat Ank PF00023.25 EMR63100.1 - 8.5e-36 120.0 4.9 0.00025 20.6 0.0 9.7 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 EMR63100.1 - 2.6e-35 119.6 0.1 0.00077 19.6 0.0 9.1 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR63100.1 - 5.7e-31 106.3 2.8 2.5e-07 31.0 0.0 7.8 5 2 3 8 8 8 7 Ankyrin repeats (many copies) SPRY PF00622.23 EMR63100.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 SPRY domain SRI PF08236.6 EMR63100.1 - 0.024 14.5 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Thr_synth_N PF14821.1 EMR63100.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonine synthase N terminus WD40 PF00400.27 EMR63101.1 - 1.2e-67 221.5 19.2 3.7e-12 45.6 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tbf5 PF06331.7 EMR63101.1 - 1.3e-19 69.6 1.0 2.4e-19 68.8 0.7 1.4 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Nup160 PF11715.3 EMR63101.1 - 1.2e-09 36.8 3.9 0.00027 19.2 0.1 4.1 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMR63101.1 - 0.0026 16.5 1.3 3.5 6.2 0.0 3.4 1 1 3 4 4 4 2 Nup133 N terminal like LisH PF08513.6 EMR63101.1 - 0.0055 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 LisH Ank_2 PF12796.2 EMR63102.1 - 1.2e-10 41.5 0.6 1.4e-08 34.9 0.4 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMR63102.1 - 1.7e-09 37.5 2.8 5.2e-06 26.5 0.2 3.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EMR63102.1 - 3.6e-08 32.8 0.4 0.0017 18.0 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMR63102.1 - 6.3e-07 29.7 1.4 0.012 16.0 0.0 4.3 4 2 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR63102.1 - 1.6e-06 27.7 2.2 0.00065 19.7 0.0 4.6 5 1 0 5 5 5 1 Ankyrin repeat SLA_LP_auto_ag PF05889.8 EMR63102.1 - 0.091 11.2 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Frataxin_Cyay PF01491.11 EMR63103.1 - 2.6e-21 75.4 0.0 3.2e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain DUF3632 PF12311.3 EMR63104.1 - 7.8e-36 123.5 0.1 9.5e-36 123.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Fic PF02661.13 EMR63106.1 - 6.2e-17 62.0 0.0 1.3e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family Glyco_transf_15 PF01793.11 EMR63106.1 - 0.066 12.1 0.0 0.14 11.0 0.0 1.5 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase Pil1 PF13805.1 EMR63107.1 - 2.4e-155 515.5 0.7 3.1e-155 515.1 0.5 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EMR63107.1 - 0.029 13.7 3.0 0.054 12.8 2.1 1.4 1 0 0 1 1 1 0 FAM92 protein Gas_vesicle_C PF01304.12 EMR63107.1 - 0.058 13.0 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain APG6 PF04111.7 EMR63107.1 - 0.26 10.2 2.9 7.1 5.5 0.5 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 SET PF00856.23 EMR63108.1 - 2.4e-23 83.1 0.4 2.4e-23 83.1 0.2 3.0 2 2 0 2 2 2 1 SET domain Abhydrolase_3 PF07859.8 EMR63110.1 - 5.2e-12 45.7 0.2 7.1e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMR63110.1 - 6.9e-10 38.4 0.0 4.4e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMR63110.1 - 2.6e-08 34.0 5.8 3.9e-08 33.4 4.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR63110.1 - 3.4e-08 33.3 0.2 5e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMR63110.1 - 1.7e-07 30.7 0.0 2.5e-05 23.6 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EMR63110.1 - 0.004 16.7 0.0 2.7 7.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF829 PF05705.9 EMR63110.1 - 0.0058 16.3 0.0 0.0076 15.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF2048 PF09752.4 EMR63110.1 - 0.014 14.2 0.2 0.023 13.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) BAAT_C PF08840.6 EMR63110.1 - 0.031 13.9 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.5 EMR63110.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein YjeF_N PF03853.10 EMR63110.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Esterase_phd PF10503.4 EMR63110.1 - 0.087 12.0 0.7 7.5 5.7 0.2 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Peptidase_S15 PF02129.13 EMR63110.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LIP PF03583.9 EMR63110.1 - 0.17 11.0 0.2 0.35 10.0 0.0 1.5 2 0 0 2 2 2 0 Secretory lipase SLT PF01464.15 EMR63111.1 - 4.7e-12 45.4 0.1 7.9e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain p450 PF00067.17 EMR63112.1 - 7.5e-05 21.4 0.0 8.6e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L44 PF00935.14 EMR63113.1 - 2.8e-35 120.1 10.5 4.1e-35 119.6 7.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 EMR63113.1 - 4.6 7.5 8.8 1.4 9.1 0.9 2.7 2 1 0 2 2 2 0 Ribosomal protein L33 Terpene_synth_C PF03936.11 EMR63114.1 - 1.3e-15 57.3 0.0 2e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Ctr PF04145.10 EMR63115.1 - 3e-31 108.4 0.6 3.4e-31 108.2 0.4 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Cytadhesin_P30 PF07271.6 EMR63115.1 - 0.15 11.3 0.1 0.26 10.5 0.1 1.4 1 1 0 1 1 1 0 Cytadhesin P30/P32 MFS_1 PF07690.11 EMR63116.1 - 3.2e-22 78.7 55.8 2.1e-15 56.2 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Lamp PF01299.12 EMR63116.1 - 3.3 6.7 3.7 5.1 6.1 2.6 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Asp PF00026.18 EMR63118.1 - 1e-63 215.5 1.2 1.2e-63 215.2 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMR63118.1 - 4.2e-11 43.0 1.2 1.6e-10 41.1 0.4 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EMR63118.1 - 0.031 13.8 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal FMO-like PF00743.14 EMR63119.1 - 4.3e-26 91.2 0.0 8.8e-11 40.6 0.0 3.2 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMR63119.1 - 1.1e-16 61.5 0.0 3.7e-15 56.5 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR63119.1 - 5.7e-08 32.0 0.0 0.027 13.4 0.0 3.8 4 0 0 4 4 4 3 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMR63119.1 - 8.4e-07 29.0 0.0 0.00024 21.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR63119.1 - 1.2e-05 25.1 0.1 0.00044 20.0 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EMR63119.1 - 0.00034 20.5 0.0 0.00094 19.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMR63119.1 - 0.033 13.2 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.15 EMR63119.1 - 0.11 12.6 0.7 0.43 10.6 0.0 2.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EMR63119.1 - 0.11 12.7 0.0 4.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Cornichon PF03311.9 EMR63120.1 - 2.9e-55 185.8 10.6 3.3e-55 185.6 7.3 1.0 1 0 0 1 1 1 1 Cornichon protein Ribosomal_S8 PF00410.14 EMR63121.1 - 2.3e-17 63.0 0.0 3.2e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Dabb PF07876.7 EMR63123.1 - 1.1e-18 67.4 0.0 1.2e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Aminotran_1_2 PF00155.16 EMR63124.1 - 1.2e-40 139.5 0.0 1.9e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMR63124.1 - 2.8e-07 29.1 0.0 4.3e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EMR63124.1 - 7.1e-07 28.6 0.0 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EMR63124.1 - 8.5e-07 28.0 0.0 2e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_MocR PF12897.2 EMR63124.1 - 2.6e-05 22.9 0.0 3.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EMR63124.1 - 0.00021 20.4 0.1 0.00034 19.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 EMR63124.1 - 0.07 11.7 0.0 0.29 9.7 0.0 1.8 2 0 0 2 2 2 0 Allinase WD40 PF00400.27 EMR63125.1 - 1.3e-39 132.6 7.8 9.8e-09 34.7 0.0 7.3 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EMR63125.1 - 0.00045 19.9 0.5 1.3 8.7 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EMR63125.1 - 0.003 15.7 0.7 0.41 8.7 0.0 2.7 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EMR63125.1 - 0.15 10.8 0.1 0.4 9.4 0.0 1.7 2 1 0 2 2 2 0 Coatomer WD associated region ABC2_membrane PF01061.19 EMR63127.1 - 1.1e-36 126.0 20.6 2.1e-36 125.0 14.2 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EMR63127.1 - 1.2e-24 87.1 0.0 2.6e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMR63127.1 - 8.1e-09 35.8 0.0 4e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EMR63127.1 - 5.5e-06 25.6 26.2 5.5e-06 25.6 18.2 2.2 1 1 1 2 2 2 1 ABC-2 family transporter protein hEGF PF12661.2 EMR63127.1 - 2.4e-05 24.1 20.7 0.0086 16.0 2.2 4.3 3 0 0 3 3 3 2 Human growth factor-like EGF ABC2_membrane_2 PF12679.2 EMR63127.1 - 0.00013 20.8 17.5 0.0016 17.3 4.0 2.4 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_15 PF13175.1 EMR63127.1 - 0.0038 16.3 0.0 0.63 9.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EMR63127.1 - 0.0045 16.4 0.1 0.0099 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EMR63127.1 - 0.0046 16.3 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMR63127.1 - 0.0083 15.3 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMR63127.1 - 0.018 15.1 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMR63127.1 - 0.043 14.6 0.0 0.096 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMR63127.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EMR63127.1 - 0.049 13.9 0.1 0.09 13.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMR63127.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMR63127.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EMR63127.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain SurE PF01975.12 EMR63128.1 - 1.6e-39 135.2 0.0 2.2e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE NGP1NT PF08153.7 EMR63129.1 - 4.8e-47 159.1 0.5 8.2e-47 158.4 0.3 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EMR63129.1 - 3.3e-19 68.9 0.0 1.4e-14 53.9 0.0 2.5 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMR63129.1 - 7.7e-05 22.5 0.2 0.32 10.8 0.0 3.4 2 1 1 3 3 3 2 Dynamin family FeoB_N PF02421.13 EMR63129.1 - 8.4e-05 21.9 0.1 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EMR63129.1 - 0.00055 19.4 0.1 0.092 12.1 0.0 3.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EMR63129.1 - 0.00085 18.6 0.2 0.32 10.2 0.0 2.5 1 1 1 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 EMR63129.1 - 0.00089 18.4 0.0 0.0033 16.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 PAN_4 PF14295.1 EMR63130.1 - 4.1e-06 26.3 3.0 1.3e-05 24.7 2.1 2.0 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EMR63130.1 - 0.0016 18.1 0.4 0.004 16.8 0.2 1.6 1 0 0 1 1 1 1 PAN domain DUF2668 PF10873.3 EMR63130.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Herpes_US9 PF06072.6 EMR63130.1 - 0.49 10.2 2.6 0.9 9.4 1.8 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 FMN_red PF03358.10 EMR63131.1 - 1.8e-10 40.5 0.0 2.3e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EMR63131.1 - 1e-09 38.5 0.1 2.4e-09 37.3 0.1 1.8 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EMR63131.1 - 2.8e-07 30.2 0.0 3.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EMR63131.1 - 0.00016 21.6 0.0 0.0032 17.4 0.0 2.1 1 1 1 2 2 2 1 Flavodoxin domain Flavodoxin_4 PF12682.2 EMR63131.1 - 0.0037 16.6 0.0 0.031 13.6 0.0 2.2 1 1 0 1 1 1 1 Flavodoxin G_glu_transpept PF01019.16 EMR63132.1 - 2.5e-164 547.5 0.4 2.9e-164 547.3 0.2 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase But2 PF09792.4 EMR63133.1 - 4.2e-17 62.2 0.0 5.2e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain GLTT PF01744.15 EMR63135.1 - 5.9e-07 28.7 4.9 5.9e-07 28.7 3.4 2.1 2 0 0 2 2 2 1 GLTT repeat (6 copies) Exo_endo_phos PF03372.18 EMR63136.1 - 1.2e-10 41.7 0.7 1.8e-10 41.1 0.5 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NAD_binding_10 PF13460.1 EMR63137.1 - 6.9e-14 52.2 0.0 1.1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR63137.1 - 6.2e-10 38.9 0.0 2e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EMR63137.1 - 0.011 16.1 0.2 0.18 12.2 0.1 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 EMR63137.1 - 0.015 14.5 0.1 0.028 13.6 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.7 EMR63137.1 - 0.021 13.7 0.2 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein FGF-BP1 PF06473.7 EMR63138.1 - 0.85 9.1 4.0 0.88 9.1 2.7 1.0 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Mucin PF01456.12 EMR63138.1 - 1.4 8.7 10.6 1.5 8.5 7.4 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein GTP_EFTU PF00009.22 EMR63139.1 - 1.5e-56 190.8 0.2 3.1e-56 189.8 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EMR63139.1 - 3.9e-31 106.7 0.0 7.4e-31 105.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EMR63139.1 - 1.1e-30 105.6 0.0 2.4e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EMR63139.1 - 4.3e-23 80.9 0.0 1.2e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMR63139.1 - 6.3e-14 51.8 0.0 1.5e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF442 PF04273.8 EMR63139.1 - 0.0057 16.5 0.1 0.18 11.6 0.0 3.0 2 0 0 2 2 2 1 Putative phosphatase (DUF442) Peptidase_M24 PF00557.19 EMR63141.1 - 7.5e-43 146.5 0.0 9.4e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EMR63141.1 - 0.00043 20.0 5.1 0.00043 20.0 3.6 2.3 2 0 0 2 2 2 1 MYND finger CR6_interact PF10147.4 EMR63142.1 - 0.00075 18.8 1.7 0.0013 18.1 1.2 1.4 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Protocadherin PF08374.6 EMR63142.1 - 0.031 13.9 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.1 EMR63142.1 - 0.052 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 EMR63142.1 - 0.075 13.2 0.7 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator SpoIIIAH PF12685.2 EMR63142.1 - 0.08 12.4 0.1 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Ctr PF04145.10 EMR63142.1 - 0.81 9.7 2.1 1.1 9.2 0.0 2.0 2 1 0 2 2 2 0 Ctr copper transporter family Iso_dh PF00180.15 EMR63143.1 - 7.5e-96 321.0 0.0 1.5e-95 320.1 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase A_deamin PF02137.13 EMR63144.1 - 6.7e-56 190.0 0.0 4.4e-55 187.3 0.0 2.2 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain MxiH PF09392.5 EMR63148.1 - 0.042 14.4 0.8 3.4 8.3 0.0 2.9 2 1 0 2 2 2 0 Type III secretion needle MxiH like DASH_Dad2 PF08654.5 EMR63148.1 - 0.077 12.9 2.0 0.34 10.9 0.0 2.9 3 1 1 4 4 4 0 DASH complex subunit Dad2 Antimicrobial_3 PF08025.6 EMR63148.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Spider antimicrobial peptide Cluap1 PF10234.4 EMR63148.1 - 1.2 8.3 4.8 0.98 8.5 0.1 2.7 3 1 0 3 3 3 0 Clusterin-associated protein-1 PHD PF00628.24 EMR63148.1 - 2 8.1 10.7 2.8 7.6 7.0 1.6 1 1 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.1 EMR63149.1 - 7.5e-07 28.7 13.9 1.3e-06 27.9 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAM24 PF15193.1 EMR63149.1 - 0.08 13.1 5.4 0.16 12.1 3.7 1.5 1 0 0 1 1 1 0 FAM24 family zf-C2H2_2 PF12756.2 EMR63150.1 - 6.3e-25 87.2 5.0 6.3e-25 87.2 3.5 1.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EMR63150.1 - 0.036 14.2 1.0 0.036 14.2 0.7 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RNase_PH PF01138.16 EMR63151.1 - 4.3e-28 98.2 0.1 9.2e-28 97.1 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Glyco_trans_1_4 PF13692.1 EMR63151.1 - 0.0092 16.1 0.0 0.056 13.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 tRNA_int_endo PF01974.12 EMR63152.1 - 1.8e-13 50.0 0.0 3.8e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF605 PF04652.11 EMR63152.1 - 0.058 12.7 8.1 0.074 12.4 5.6 1.1 1 0 0 1 1 1 0 Vta1 like FimP PF09766.4 EMR63153.1 - 4.1e-28 98.4 10.7 5e-28 98.2 7.4 1.1 1 0 0 1 1 1 1 Fms-interacting protein K-box PF01486.12 EMR63153.1 - 0.011 15.4 1.2 0.011 15.4 0.8 3.3 2 2 1 3 3 3 0 K-box region CENP-F_leu_zip PF10473.4 EMR63153.1 - 0.11 12.3 12.2 0.32 10.8 3.5 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SusD PF07980.6 EMR63153.1 - 0.22 10.9 0.9 0.3 10.5 0.6 1.2 1 0 0 1 1 1 0 SusD family Pinin_SDK_memA PF04696.8 EMR63153.1 - 2.1 7.9 12.3 1.1 8.9 4.0 2.3 2 1 0 2 2 2 0 pinin/SDK/memA/ protein conserved region PP28 PF10252.4 EMR63153.1 - 3.9 7.5 12.1 0.55 10.2 2.7 2.4 2 1 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 DUF4200 PF13863.1 EMR63153.1 - 5.1 7.0 17.1 2.6 7.9 1.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) RabGAP-TBC PF00566.13 EMR63154.1 - 6.2e-31 107.5 0.0 4.8e-26 91.5 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Ammonium_transp PF00909.16 EMR63155.1 - 2.8e-113 378.4 29.5 3.2e-113 378.2 20.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HlyIII PF03006.15 EMR63156.1 - 2.1e-56 190.8 21.3 2.6e-56 190.5 14.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Phage_lysis PF03245.8 EMR63156.1 - 0.061 13.3 0.6 0.11 12.5 0.4 1.3 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Pol_alpha_B_N PF08418.5 EMR63157.1 - 0.023 14.2 0.1 0.023 14.2 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal U3_assoc_6 PF08640.6 EMR63157.1 - 0.05 13.3 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 DUF1117 PF06547.7 EMR63157.1 - 2.9 7.9 10.9 1.1 9.3 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) SR-25 PF10500.4 EMR63157.1 - 4.4 6.6 23.6 0.91 8.9 7.9 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CRT10 PF08728.5 EMR63158.1 - 0.15 10.0 0.0 0.19 9.6 0.0 1.1 1 0 0 1 1 1 0 CRT10 Sporozoite_P67 PF05642.6 EMR63158.1 - 0.27 9.0 0.5 0.36 8.6 0.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TauD PF02668.11 EMR63159.1 - 1.9e-08 34.3 0.3 2.3e-08 34.0 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EMR63159.1 - 0.024 13.5 0.2 0.03 13.2 0.2 1.1 1 0 0 1 1 1 0 CsiD Sulfate_transp PF00916.15 EMR63161.1 - 3.2e-74 249.4 11.5 5.9e-74 248.5 8.0 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMR63161.1 - 8.8e-31 105.4 3.1 8.8e-31 105.4 2.1 3.3 3 1 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMR63161.1 - 6.3e-09 35.2 0.0 1.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 STAS domain Yip1 PF04893.12 EMR63162.1 - 8.9e-13 48.0 14.3 1.2e-12 47.6 9.9 1.1 1 0 0 1 1 1 1 Yip1 domain Nuc_sug_transp PF04142.10 EMR63162.1 - 0.08 12.0 0.8 0.12 11.4 0.6 1.3 1 0 0 1 1 1 0 Nucleotide-sugar transporter RNA_pol_Rpb4 PF03874.11 EMR63163.1 - 4.7e-27 94.3 5.7 5.5e-27 94.1 4.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 TerB PF05099.8 EMR63163.1 - 0.042 13.5 0.4 0.08 12.6 0.3 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TerB dsDNA_bind PF01984.15 EMR63163.1 - 0.091 12.7 2.6 0.59 10.1 0.0 2.4 2 1 0 2 2 2 0 Double-stranded DNA-binding domain Spexin PF15171.1 EMR63163.1 - 0.13 12.2 0.3 0.27 11.2 0.1 1.6 2 0 0 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin RabGAP-TBC PF00566.13 EMR63164.1 - 5.7e-21 74.9 0.0 7.6e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF35_N PF12172.3 EMR63165.1 - 0.023 14.6 0.9 0.091 12.7 0.6 2.1 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) RRN7 PF11781.3 EMR63165.1 - 0.14 11.6 3.2 0.34 10.4 2.2 1.7 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Arv1 PF04161.8 EMR63166.1 - 7.6e-47 159.9 0.0 9.9e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family TPR_10 PF13374.1 EMR63167.1 - 1.2e-07 31.3 0.4 5.4e-07 29.3 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMR63167.1 - 2.8e-07 30.3 0.1 1.3e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_22 PF13401.1 EMR63167.1 - 9.9e-06 25.7 0.0 3.4e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EMR63167.1 - 4.2e-05 22.5 0.0 6.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EMR63167.1 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EMR63167.1 - 0.0017 17.8 0.0 0.0037 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EMR63167.1 - 0.097 11.6 0.0 7.5 5.4 0.0 2.2 2 0 0 2 2 2 0 Anion-transporting ATPase DUF619 PF04768.8 EMR63168.1 - 2.8e-49 166.7 0.0 4.5e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Methyltransf_11 PF08241.7 EMR63169.1 - 3.7e-12 46.5 0.0 8.5e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR63169.1 - 9.5e-06 25.4 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR63169.1 - 0.013 15.8 0.0 0.037 14.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EMR63169.1 - 0.016 15.6 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EMR63169.1 - 0.049 14.2 0.0 0.23 12.0 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Ubie_methyltran PF01209.13 EMR63169.1 - 0.2 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Sybindin PF04099.7 EMR63170.1 - 5.7e-49 165.4 0.0 7.2e-49 165.1 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EMR63170.1 - 2.6e-09 37.0 0.0 2.7e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Alk_phosphatase PF00245.15 EMR63171.1 - 3.8e-75 253.1 0.0 1.9e-36 125.6 0.0 2.0 1 1 1 2 2 2 2 Alkaline phosphatase Glycos_transf_4 PF00953.16 EMR63172.1 - 9.7e-32 109.9 10.7 9.7e-32 109.9 7.4 1.9 2 1 0 2 2 2 1 Glycosyl transferase family 4 ATP_synt_H PF05493.8 EMR63173.1 - 5.1e-27 93.7 1.9 5.7e-27 93.5 1.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 EMR63173.1 - 0.0079 15.6 0.8 0.0081 15.5 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) OppC_N PF12911.2 EMR63173.1 - 0.011 15.0 0.0 0.37 10.2 0.0 2.0 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF1129 PF06570.6 EMR63173.1 - 0.014 14.7 0.4 0.015 14.5 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) ABC2_membrane_2 PF12679.2 EMR63173.1 - 0.025 13.4 2.4 0.029 13.2 1.7 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein MFS_1 PF07690.11 EMR63173.1 - 0.036 12.7 0.9 0.037 12.7 0.6 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF2142 PF09913.4 EMR63173.1 - 0.059 12.0 0.3 0.062 11.9 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) 5TM-5TMR_LYT PF07694.7 EMR63173.1 - 0.12 11.7 1.4 0.13 11.5 1.0 1.0 1 0 0 1 1 1 0 5TMR of 5TMR-LYT ABC2_membrane_4 PF12730.2 EMR63173.1 - 0.42 9.7 3.4 0.48 9.5 2.3 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein eIF-5a PF01287.15 EMR63174.1 - 2.6e-26 91.3 1.5 3.7e-26 90.8 1.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 EMR63174.1 - 0.0049 16.7 0.5 0.011 15.5 0.0 1.9 3 0 0 3 3 3 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 EMR63174.1 - 0.0083 15.8 0.3 0.02 14.6 0.2 1.7 1 0 0 1 1 1 1 KOW motif NAD_binding_2 PF03446.10 EMR63175.1 - 7.3e-29 100.7 0.1 1.3e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EMR63175.1 - 6.8e-10 39.1 0.0 1.1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EMR63175.1 - 7.2e-10 39.1 0.2 1.9e-09 37.8 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 EMR63175.1 - 1.6e-09 37.8 0.1 3e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Saccharop_dh PF03435.13 EMR63175.1 - 2.9e-05 23.2 0.0 3.7e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EMR63175.1 - 5.9e-05 23.0 0.2 0.00015 21.6 0.1 1.7 1 1 0 1 1 1 1 TrkA-N domain OCD_Mu_crystall PF02423.10 EMR63175.1 - 0.00083 18.2 0.1 0.0013 17.6 0.1 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.17 EMR63175.1 - 0.0094 16.4 0.0 0.026 15.0 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Vps52 PF04129.7 EMR63176.1 - 1.7e-120 402.9 0.0 2.3e-120 402.5 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EMR63176.1 - 1.7e-05 23.2 2.5 0.00012 20.4 1.7 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec3 Mer2 PF09074.5 EMR63176.1 - 0.027 14.3 0.1 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 Mer2 DUF1664 PF07889.7 EMR63176.1 - 0.081 12.7 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CPSF_A PF03178.10 EMR63177.1 - 0.06 12.4 0.0 7.5 5.5 0.0 2.1 2 0 0 2 2 2 0 CPSF A subunit region DUF3417 PF11897.3 EMR63177.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) VWA_2 PF13519.1 EMR63178.1 - 2.8e-11 43.8 0.1 4.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EMR63178.1 - 3.4e-10 39.8 0.1 4.8e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 EMR63178.1 - 3.3e-05 23.6 0.2 4.9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EMR63178.1 - 0.00028 20.1 1.0 0.00097 18.5 0.7 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif GTP_EFTU PF00009.22 EMR63179.1 - 3.4e-32 111.4 0.0 1.3e-31 109.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EMR63179.1 - 4.4e-18 65.1 0.0 1.1e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EMR63179.1 - 3.6e-09 36.5 10.6 5.9e-08 32.7 0.3 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMR63179.1 - 2.8e-06 27.2 0.1 1.3e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EMR63179.1 - 0.0024 17.4 0.1 0.0094 15.5 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Miro PF08477.8 EMR63179.1 - 0.0032 17.9 0.4 0.016 15.7 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein TrkA_C PF02080.16 EMR63179.1 - 0.026 14.1 1.6 0.7 9.5 0.1 3.2 3 0 0 3 3 3 0 TrkA-C domain AAA_16 PF13191.1 EMR63179.1 - 0.097 12.6 0.0 0.097 12.6 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain Nbl1_Borealin_N PF10444.4 EMR63180.1 - 8e-22 76.3 6.0 1.5e-21 75.4 4.2 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Radical_SAM PF04055.16 EMR63181.1 - 2.9e-08 34.0 0.0 4.6e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EMR63181.1 - 6.4e-06 26.3 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EMR63181.1 - 0.0007 19.6 0.1 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain FGGY_C PF02782.11 EMR63181.1 - 0.053 13.1 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain WD40 PF00400.27 EMR63182.1 - 3.6e-21 74.1 0.2 9e-06 25.3 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat BNR PF02012.15 EMR63182.1 - 1.4 9.0 6.5 0.16 11.9 0.8 2.5 2 0 0 2 2 2 0 BNR/Asp-box repeat adh_short PF00106.20 EMR63183.1 - 9.2e-19 67.9 0.0 1.2e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR63183.1 - 1.4e-12 47.9 0.0 1.6e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR63183.1 - 4e-08 33.1 0.0 5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 KR domain HSP70 PF00012.15 EMR63184.1 - 4.4e-166 553.3 5.4 4.4e-166 553.3 3.7 2.3 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EMR63184.1 - 2.2e-11 42.9 0.0 1.4e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 EMR63184.1 - 0.002 17.9 1.0 0.47 10.3 0.0 3.1 2 2 0 2 2 2 2 Cell division protein FtsA GMC_oxred_N PF00732.14 EMR63185.1 - 2e-68 230.7 0.0 2.5e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR63185.1 - 4.7e-29 101.5 0.0 7.7e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMR63185.1 - 0.00029 19.8 2.9 0.0054 15.6 0.4 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR63185.1 - 0.0021 18.0 0.3 0.0052 16.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMR63185.1 - 0.057 12.3 0.0 0.094 11.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EMR63185.1 - 0.17 10.6 1.2 0.72 8.6 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain ubiquitin PF00240.18 EMR63186.1 - 1.3e-34 117.3 0.9 1.7e-34 117.0 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EMR63186.1 - 3.1e-30 103.5 9.6 4.8e-30 102.9 6.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EMR63186.1 - 5.1e-19 67.7 0.5 7.1e-19 67.2 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMR63186.1 - 8.2e-06 25.9 0.1 3.2e-05 24.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EMR63186.1 - 0.00067 19.3 0.0 0.00096 18.8 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EMR63186.1 - 0.0091 15.8 0.0 0.017 14.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMR63186.1 - 0.014 15.6 0.1 0.014 15.6 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EMR63186.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Peptidase_S10 PF00450.17 EMR63187.1 - 3.8e-89 299.7 0.5 5e-89 299.3 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Aldo_ket_red PF00248.16 EMR63188.1 - 7.9e-43 146.2 0.0 9.6e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CRAL_TRIO PF00650.15 EMR63189.1 - 3.4e-22 78.6 0.0 9.4e-22 77.1 0.0 1.7 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMR63189.1 - 7.6e-12 45.1 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ThiF PF00899.16 EMR63190.1 - 3.6e-37 127.2 0.3 1.1e-36 125.7 0.0 1.7 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EMR63190.1 - 4.7e-28 96.7 0.1 8.6e-28 95.9 0.0 1.5 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EMR63190.1 - 1.1e-25 89.0 0.2 2e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein Shikimate_DH PF01488.15 EMR63190.1 - 0.00011 22.3 0.1 0.00031 20.8 0.1 1.8 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.1 EMR63190.1 - 0.00041 20.4 0.0 0.0021 18.1 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_C PF09358.5 EMR63190.1 - 0.0065 16.6 0.0 0.017 15.2 0.0 1.7 2 0 0 2 2 1 1 Ubiquitin-activating enzyme e1 C-terminal domain MoeZ_MoeB PF05237.8 EMR63190.1 - 0.037 13.6 0.1 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 MoeZ/MoeB domain DUF3419 PF11899.3 EMR63190.1 - 0.078 11.6 0.1 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) DAO PF01266.19 EMR63190.1 - 0.08 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 EMR63190.1 - 0.087 12.2 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EMR63190.1 - 0.094 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 EMR63190.1 - 0.095 13.1 0.1 0.27 11.6 0.0 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Ecm33 PF12454.3 EMR63190.1 - 0.098 12.5 3.1 0.2 11.5 2.1 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein F-box PF00646.28 EMR63191.1 - 2.3e-08 33.4 1.7 2.9e-07 29.9 0.1 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EMR63191.1 - 3.5e-08 33.0 3.0 3.7e-07 29.7 0.2 2.7 2 0 0 2 2 2 1 F-box-like Corona_S2 PF01601.11 EMR63192.1 - 0.011 13.8 0.1 0.014 13.5 0.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF4398 PF14346.1 EMR63192.1 - 0.027 14.5 0.6 0.034 14.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) Chalcone PF02431.10 EMR63192.1 - 0.058 12.7 0.0 0.067 12.5 0.0 1.1 1 0 0 1 1 1 0 Chalcone-flavanone isomerase DUF1523 PF07509.6 EMR63192.1 - 0.066 12.4 0.6 0.11 11.7 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1523) Pex2_Pex12 PF04757.9 EMR63193.1 - 3.6e-55 186.8 2.2 4.5e-55 186.5 1.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EMR63193.1 - 0.0017 18.3 2.5 0.003 17.5 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMR63193.1 - 0.0031 17.3 1.3 0.0052 16.5 0.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMR63193.1 - 0.022 14.3 1.1 0.033 13.8 0.8 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMR63193.1 - 0.097 12.3 1.8 0.17 11.5 1.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMR63193.1 - 0.2 11.5 1.8 0.35 10.7 1.3 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_3 PF14369.1 EMR63193.1 - 2.6 8.0 5.7 1 9.4 0.3 2.3 2 0 0 2 2 2 0 zinc-finger DDHD PF02862.12 EMR63194.1 - 0.68 9.6 3.3 0.78 9.4 2.3 1.1 1 0 0 1 1 1 0 DDHD domain Glyoxalase PF00903.20 EMR63195.1 - 2.2e-06 27.6 5.6 8.6e-06 25.7 0.9 2.7 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMR63195.1 - 0.0007 20.1 1.8 0.089 13.4 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain BioW PF03744.8 EMR63195.1 - 0.032 13.6 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase TPR_1 PF00515.23 EMR63195.1 - 0.13 11.8 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EMR63196.1 - 4.5e-26 92.1 3.7 8.1e-26 91.3 2.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR63196.1 - 3.3e-15 56.2 0.0 2.2e-10 40.5 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR63196.1 - 6.1e-12 45.5 0.0 2.1e-11 43.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMR63196.1 - 0.0025 17.1 0.1 0.41 9.8 0.0 2.5 2 1 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.3 EMR63196.1 - 0.0039 17.0 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EMR63196.1 - 0.14 11.5 0.0 18 4.7 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF4360 PF14273.1 EMR63197.1 - 5.2e-16 58.8 0.1 6.2e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) SH3_9 PF14604.1 EMR63198.1 - 1.1e-08 34.4 0.5 1.1e-07 31.3 0.4 2.4 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.12 EMR63198.1 - 0.00035 19.9 0.4 0.00067 19.0 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMR63198.1 - 0.032 13.6 2.9 0.11 11.9 1.7 2.0 2 0 0 2 2 2 0 SH3 domain Pyr_redox_3 PF13738.1 EMR63199.1 - 3e-20 73.1 0.0 6.9e-19 68.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR63199.1 - 1.9e-11 42.8 0.2 6.9e-11 41.0 0.1 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMR63199.1 - 1e-09 37.7 0.1 1.6e-06 27.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMR63199.1 - 8e-09 35.6 0.0 1.6e-07 31.3 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMR63199.1 - 5.1e-08 32.3 0.0 0.00038 19.6 0.0 3.1 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.22 EMR63199.1 - 3.3e-07 30.6 0.1 0.004 17.5 0.0 3.6 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR63199.1 - 4.9e-05 23.2 0.0 0.0014 18.6 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 EMR63199.1 - 0.0008 18.6 0.1 0.01 15.0 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 EMR63199.1 - 0.003 16.6 0.0 0.5 9.4 0.0 2.5 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EMR63199.1 - 0.0051 15.7 0.3 0.81 8.5 0.0 3.2 4 0 0 4 4 4 1 FAD dependent oxidoreductase SnoaL_4 PF13577.1 EMR63199.1 - 0.0084 16.0 1.2 0.091 12.6 0.9 2.6 1 1 0 1 1 1 1 SnoaL-like domain FAD_binding_2 PF00890.19 EMR63199.1 - 0.013 14.3 0.0 0.04 12.7 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EMR63199.1 - 0.027 13.4 0.1 0.088 11.7 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein DUF928 PF06051.7 EMR63199.1 - 0.038 13.5 0.1 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) SnoaL_2 PF12680.2 EMR63199.1 - 0.068 13.5 1.3 0.46 10.9 0.0 2.9 3 1 0 3 3 3 0 SnoaL-like domain NAD_binding_9 PF13454.1 EMR63199.1 - 0.11 12.2 0.6 44 3.8 0.0 3.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding CPSase_L_chain PF00289.17 EMR63199.1 - 0.13 12.3 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Telomere_reg-2 PF10193.4 EMR63200.1 - 3e-39 133.8 0.0 8.5e-39 132.3 0.0 1.8 1 0 0 1 1 1 1 Telomere length regulation protein Tannase PF07519.6 EMR63201.1 - 1.2e-87 294.5 0.3 1.5e-87 294.3 0.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 EMR63201.1 - 0.035 13.3 0.0 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family KR PF08659.5 EMR63202.1 - 4.2e-59 199.2 0.1 1.1e-58 197.8 0.0 1.8 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR63202.1 - 6.1e-49 166.1 0.2 1.9e-48 164.5 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 EMR63202.1 - 2.3e-48 165.1 0.1 4.2e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EMR63202.1 - 5.5e-44 150.5 0.0 6.3e-35 120.8 0.0 2.5 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMR63202.1 - 3.1e-35 120.5 0.4 1.1e-34 118.7 0.3 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EMR63202.1 - 3.6e-27 95.3 0.0 6.2e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 EMR63202.1 - 1.2e-09 37.7 0.0 3.8e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EMR63202.1 - 5.7e-05 23.2 0.0 0.00017 21.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site PSCyt2 PF07583.6 EMR63202.1 - 0.38 10.2 0.0 0.78 9.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) Esterase_phd PF10503.4 EMR63203.1 - 7e-08 31.9 0.5 1.6e-06 27.5 0.0 3.1 2 1 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EMR63203.1 - 3.8e-06 26.7 0.0 8.4e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR63203.1 - 0.00065 18.9 0.1 0.0013 17.9 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 EMR63203.1 - 0.014 13.9 0.0 0.048 12.1 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) G-alpha PF00503.15 EMR63204.1 - 1.7e-55 188.3 0.0 1.9e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMR63204.1 - 0.007 15.6 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_29 PF13555.1 EMR63204.1 - 0.02 14.3 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 EMR63205.1 - 3.2e-17 62.9 0.0 6.4e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMR63205.1 - 9e-05 23.2 0.0 0.00045 21.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMR63205.1 - 0.0013 18.8 0.0 0.0094 16.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EMR63205.1 - 0.0035 16.7 0.0 0.01 15.2 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 EMR63205.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMR63205.1 - 0.035 13.8 0.0 0.094 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EMR63205.1 - 0.048 12.6 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Acid_PPase PF12689.2 EMR63206.1 - 4e-58 195.7 0.1 7.1e-58 194.9 0.0 1.4 2 0 0 2 2 2 1 Acid Phosphatase HAD_2 PF13419.1 EMR63206.1 - 0.025 14.8 0.7 5.8 7.1 0.0 3.1 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Phosphorylase PF00343.15 EMR63207.1 - 0 1069.4 0.0 0 1069.2 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase Fringe PF02434.11 EMR63207.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Fringe-like Coatomer_b_Cpla PF14806.1 EMR63207.1 - 0.082 12.6 0.1 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Fungal_trans PF04082.13 EMR63208.1 - 8.6e-18 64.1 0.8 4.1e-16 58.6 0.2 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain RNA_pol_A_bac PF01000.21 EMR63209.1 - 4.1e-25 88.1 0.0 9.1e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EMR63209.1 - 1.5e-14 52.8 0.0 1.9e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GYF PF02213.11 EMR63209.1 - 0.037 13.6 0.5 0.12 12.0 0.3 1.9 2 0 0 2 2 2 0 GYF domain RPEL PF02755.10 EMR63209.1 - 0.11 11.8 0.2 0.31 10.4 0.1 1.7 1 0 0 1 1 1 0 RPEL repeat RVT_3 PF13456.1 EMR63210.1 - 0.0007 19.3 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like zf-ZPR1 PF03367.8 EMR63211.1 - 6.1e-105 347.3 0.0 1.8e-52 176.7 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain PAF-AH_p_II PF03403.8 EMR63212.1 - 2.8e-35 121.3 0.0 8.1e-32 109.9 0.0 2.1 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EMR63212.1 - 2.5e-13 50.0 0.1 5.8e-13 48.8 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR63212.1 - 2e-09 37.6 0.1 4.6e-09 36.4 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMR63212.1 - 9e-07 28.0 0.2 9e-06 24.7 0.1 2.0 1 1 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EMR63212.1 - 0.0015 17.8 0.1 0.17 11.0 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EMR63212.1 - 0.0016 18.2 0.1 0.015 15.1 0.0 2.3 2 0 0 2 2 2 1 Putative lysophospholipase Chlorophyllase PF07224.6 EMR63212.1 - 0.0053 15.5 0.0 0.01 14.6 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_3 PF07859.8 EMR63212.1 - 0.012 15.1 0.0 0.038 13.5 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Roughex PF06020.6 EMR63213.1 - 0.083 11.5 0.1 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein PA14_2 PF10528.4 EMR63214.1 - 7e-17 61.4 0.0 1.5e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 GLEYA domain Baculo_PEP_C PF04513.7 EMR63215.1 - 0.093 12.5 13.6 0.84 9.4 9.2 2.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_72 PF03198.9 EMR63216.1 - 2.2e-72 243.7 0.0 6.1e-72 242.2 0.0 1.6 1 1 0 1 1 1 1 Glucanosyltransferase DUF1504 PF07399.6 EMR63216.1 - 0.12 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1504) DUF3040 PF11239.3 EMR63217.1 - 0.066 13.2 0.6 0.52 10.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) VanW PF04294.8 EMR63217.1 - 0.17 11.0 1.2 3.6 6.7 0.2 2.3 2 0 0 2 2 2 0 VanW like protein Ank_2 PF12796.2 EMR63219.1 - 3.2e-35 120.3 0.2 2.2e-10 40.7 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMR63219.1 - 3.2e-30 102.4 3.5 9.3e-07 28.3 0.1 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 EMR63219.1 - 1.8e-24 85.1 1.1 1.6e-07 31.3 0.0 6.4 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR63219.1 - 3.5e-22 78.3 0.1 1.6e-05 25.2 0.0 7.2 3 2 5 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR63219.1 - 7e-17 59.8 0.2 0.00091 19.2 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat TraQ PF09679.5 EMR63220.1 - 0.1 12.5 0.1 0.32 10.9 0.1 1.8 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) DNA_pol_viral_N PF00242.12 EMR63220.1 - 3.8 6.4 15.7 6.9 5.6 10.9 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain HeLo PF14479.1 EMR63221.1 - 2.3e-23 83.0 1.4 4.1e-23 82.2 1.0 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.20 EMR63221.1 - 0.0013 17.9 0.0 0.0046 16.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain GFO_IDH_MocA PF01408.17 EMR63222.1 - 1.2e-21 77.3 0.1 2.6e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EMR63222.1 - 3.6e-06 27.2 0.0 6.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ank_2 PF12796.2 EMR63223.1 - 3.4e-69 229.2 3.2 1.3e-18 67.0 0.0 5.9 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 EMR63223.1 - 4.5e-55 180.8 10.4 3.1e-06 26.7 0.1 11.1 12 0 0 12 12 12 9 Ankyrin repeat Ank_3 PF13606.1 EMR63223.1 - 1.8e-45 148.3 0.6 0.00013 21.8 0.0 11.9 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.1 EMR63223.1 - 1.4e-42 142.7 5.7 1.1e-08 34.9 0.0 6.9 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR63223.1 - 9.6e-41 137.4 4.4 1.1e-07 32.1 0.0 8.4 3 2 5 9 9 9 8 Ankyrin repeats (many copies) PIR PF00399.14 EMR63224.1 - 0.00039 19.6 27.7 0.0028 16.9 0.6 4.7 4 0 0 4 4 4 4 Yeast PIR protein repeat Totivirus_coat PF05518.6 EMR63224.1 - 1.7 6.3 13.2 2.2 6.0 9.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein HET PF06985.6 EMR63225.1 - 1.1e-33 116.3 0.2 1.9e-33 115.5 0.0 1.5 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EMR63225.1 - 7.6e-11 42.2 0.2 2.5e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMR63225.1 - 1.2e-08 34.2 0.0 7e-05 22.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EMR63225.1 - 1.8e-07 31.4 0.0 4.6e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR63225.1 - 2.5e-06 27.5 0.0 1.1e-05 25.5 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR63225.1 - 9.4e-05 22.2 0.0 0.038 14.2 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat NAD_binding_10 PF13460.1 EMR63226.1 - 4.1e-18 66.0 0.0 4.7e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR63226.1 - 2.4e-09 36.7 0.0 3.4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EMR63226.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.16 EMR63226.1 - 0.024 14.0 0.0 0.059 12.7 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EMR63226.1 - 0.14 11.1 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Bestrophin PF01062.16 EMR63228.1 - 8.1e-40 136.5 0.5 2.3e-38 131.8 0.3 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel zf-U1 PF06220.7 EMR63229.1 - 1.5e-06 27.6 0.3 2.4e-06 27.0 0.2 1.3 1 0 0 1 1 1 1 U1 zinc finger Transferase PF02458.10 EMR63230.1 - 1.8e-17 62.9 0.0 2.4e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Transferase family Tyrosinase PF00264.15 EMR63231.1 - 7.7e-33 114.5 0.1 1.1e-32 114.0 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2126 PF09899.4 EMR63232.1 - 0.0036 15.4 0.7 0.0047 15.0 0.5 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme (DUF2126) adh_short_C2 PF13561.1 EMR63235.1 - 1.2e-27 97.1 0.5 1.5e-27 96.9 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR63235.1 - 3.9e-24 85.4 0.2 1.7e-23 83.3 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR63235.1 - 9e-10 38.5 0.3 3.4e-09 36.6 0.1 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EMR63235.1 - 0.046 12.6 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_11 PF08241.7 EMR63236.1 - 0.00018 21.9 0.0 0.00074 19.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR63236.1 - 0.00033 21.1 0.1 0.00055 20.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR63236.1 - 0.0032 17.4 0.4 0.0084 16.1 0.3 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR63236.1 - 0.0066 16.1 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR63236.1 - 0.055 13.0 0.0 0.085 12.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EMR63236.1 - 0.094 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain adh_short_C2 PF13561.1 EMR63237.1 - 9.4e-12 45.2 0.0 1.6e-06 28.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR63237.1 - 1.4e-11 44.5 0.0 1.8e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR63237.1 - 0.00012 21.7 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR63237.1 - 0.0071 16.3 0.5 0.058 13.3 0.2 2.3 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EMR63237.1 - 0.32 10.8 1.5 1.3 8.8 1.1 2.0 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase STE3 PF02076.10 EMR63238.1 - 4.1e-31 108.1 6.8 5e-26 91.4 2.0 2.1 2 0 0 2 2 2 2 Pheromone A receptor MFMR PF07777.6 EMR63238.1 - 0.023 14.6 0.1 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 G-box binding protein MFMR DUF3429 PF11911.3 EMR63238.1 - 0.19 11.7 0.0 0.19 11.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3429) Aldo_ket_red PF00248.16 EMR63239.1 - 2.4e-50 170.9 0.0 2.7e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_1 PF00232.13 EMR63240.1 - 3e-63 213.6 3.1 3.1e-61 206.9 2.1 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Erf4 PF10256.4 EMR63243.1 - 8.6e-31 106.2 0.0 1.1e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF2654 PF10849.3 EMR63244.1 - 0.21 11.3 3.6 3.5 7.4 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) adh_short PF00106.20 EMR63245.1 - 4.5e-27 95.0 0.0 5.6e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR63245.1 - 2.3e-18 66.8 0.0 3.1e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR63245.1 - 2.1e-11 43.8 0.0 3e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR63245.1 - 1.9e-06 27.9 0.0 2.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EMR63245.1 - 0.00011 21.8 0.2 0.00036 20.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EMR63245.1 - 0.0027 16.8 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Choline_transpo PF04515.7 EMR63246.1 - 1.5e-13 50.1 16.0 1.3e-11 43.9 8.9 2.1 2 0 0 2 2 2 2 Plasma-membrane choline transporter Cys_Met_Meta_PP PF01053.15 EMR63247.1 - 3.1e-146 486.5 0.0 3.6e-146 486.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EMR63247.1 - 5.2e-11 42.2 0.3 8.9e-11 41.4 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EMR63247.1 - 4.6e-10 38.7 0.1 6.1e-09 35.0 0.1 2.2 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EMR63247.1 - 1.1e-09 37.7 0.0 1.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMR63247.1 - 3.9e-09 36.0 0.0 1e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EMR63247.1 - 0.00013 20.4 0.0 0.0002 19.8 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 EMR63247.1 - 0.021 13.5 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein SLA_LP_auto_ag PF05889.8 EMR63247.1 - 0.05 12.0 0.0 0.072 11.5 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Ribosomal_60s PF00428.14 EMR63247.1 - 0.53 10.7 5.6 0.92 9.9 0.3 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein MARVEL PF01284.18 EMR63248.1 - 9.4e-15 54.6 16.3 1.2e-14 54.3 11.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Fig1 PF12351.3 EMR63248.1 - 8 6.3 8.5 10 5.9 1.1 2.1 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Ribosomal_L27e PF01777.13 EMR63249.1 - 1.2e-36 124.6 2.6 1.6e-36 124.2 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EMR63249.1 - 0.0015 18.2 0.7 0.0036 16.9 0.5 1.7 1 0 0 1 1 1 1 KOW motif Glyoxalase PF00903.20 EMR63250.1 - 2.4e-19 69.5 0.1 2e-12 47.1 0.0 2.8 2 1 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EMR63250.1 - 4.4e-15 55.6 0.1 2.2e-07 30.8 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMR63250.1 - 5.9e-12 46.1 0.2 6.7e-05 23.4 0.1 2.6 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EMR63250.1 - 2e-06 27.8 0.4 0.23 11.3 0.2 3.3 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EMR63250.1 - 0.0034 17.3 0.1 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal WW PF00397.21 EMR63251.1 - 0.0031 17.3 0.5 0.0059 16.4 0.4 1.5 1 0 0 1 1 1 1 WW domain Sugar_tr PF00083.19 EMR63252.1 - 9.5e-67 225.5 8.6 3.8e-65 220.2 5.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR63252.1 - 4.9e-24 84.7 7.9 6.2e-24 84.3 5.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF791 PF05631.9 EMR63252.1 - 9.6e-05 21.2 1.2 0.00015 20.5 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_2 PF13347.1 EMR63252.1 - 0.00025 19.5 3.8 0.00025 19.5 2.6 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 EMR63252.1 - 0.01 15.5 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 MFS_1 like family FAD_binding_3 PF01494.14 EMR63253.1 - 2e-22 79.7 3.9 5.1e-15 55.3 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EMR63253.1 - 5.4e-05 23.3 0.1 9.8e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR63253.1 - 0.00025 21.0 0.7 0.0012 18.8 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMR63253.1 - 0.0026 16.7 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EMR63253.1 - 0.0036 16.0 0.2 0.017 13.7 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EMR63253.1 - 0.0066 16.3 0.0 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR63253.1 - 0.01 14.7 3.3 0.46 9.3 0.7 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EMR63253.1 - 0.023 13.8 1.1 0.039 13.0 0.1 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EMR63253.1 - 0.033 13.0 1.4 0.059 12.2 1.0 1.4 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 EMR63253.1 - 0.048 13.4 0.1 0.091 12.5 0.1 1.4 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.22 EMR63253.1 - 0.089 13.2 0.4 0.089 13.2 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR63253.1 - 0.19 10.1 0.5 0.28 9.5 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein TPT PF03151.11 EMR63254.1 - 1.2e-28 99.6 13.0 1.2e-28 99.6 9.0 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EMR63254.1 - 0.065 12.1 25.4 0.89 8.4 17.6 2.1 1 1 0 1 1 1 0 UAA transporter family Ssl1 PF04056.9 EMR63255.1 - 2.6e-70 235.9 0.0 8.1e-70 234.3 0.0 1.7 1 1 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EMR63255.1 - 1.5e-15 56.9 7.4 1.5e-15 56.9 5.1 3.6 3 1 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.1 EMR63255.1 - 2.3e-10 40.8 0.0 3.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 EMR63255.1 - 3.4 6.8 6.7 0.89 8.7 2.3 1.7 2 0 0 2 2 2 0 Transcription factor Tfb4 TPR_11 PF13414.1 EMR63256.1 - 0.013 15.1 0.2 0.19 11.3 0.0 2.4 2 0 0 2 2 2 0 TPR repeat DUF2122 PF09895.4 EMR63256.1 - 0.037 14.2 0.0 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 RecB-family nuclease (DUF2122) HTH_Tnp_Tc3_1 PF11427.3 EMR63256.1 - 0.075 12.6 0.5 0.99 9.0 0.0 2.7 2 1 1 3 3 3 0 Tc3 transposase Chs3p PF12271.3 EMR63257.1 - 7e-95 317.3 3.7 8.6e-95 317.0 2.6 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF1218 PF06749.7 EMR63257.1 - 7.7 7.0 8.1 1.5 9.3 0.2 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1218) Ras PF00071.17 EMR63258.1 - 9.8e-48 161.5 0.0 2.6e-36 124.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EMR63258.1 - 3.6e-15 56.4 0.0 2.3e-13 50.6 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMR63258.1 - 3.4e-08 32.9 0.0 1.2e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMR63258.1 - 8e-07 28.6 0.1 3e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMR63258.1 - 2.3e-06 26.9 0.0 6.6e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMR63258.1 - 0.0015 18.4 0.0 0.0071 16.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMR63258.1 - 0.023 14.8 0.0 0.094 12.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain Antibiotic_NAT PF02522.9 EMR63258.1 - 0.031 13.5 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase AAA_16 PF13191.1 EMR63258.1 - 0.13 12.2 0.1 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF2012 PF09430.5 EMR63259.1 - 1.4e-22 79.8 0.0 2.3e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) PMT PF02366.13 EMR63260.1 - 4.2e-77 258.8 18.4 4.2e-77 258.8 12.8 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EMR63260.1 - 2e-37 128.6 0.4 3e-37 128.0 0.3 1.3 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.3 EMR63260.1 - 0.13 11.7 2.2 0.96 9.0 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DAO PF01266.19 EMR63261.1 - 8.6e-30 103.8 0.0 1.1e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glyco_hydro_76 PF03663.9 EMR63262.1 - 1.6e-113 379.8 2.4 2e-113 379.5 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Fungal_trans PF04082.13 EMR63263.1 - 6.5e-14 51.4 0.0 1.1e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR63263.1 - 1.5e-07 31.2 7.6 3e-07 30.2 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.7 EMR63263.1 - 1.5 8.5 7.8 5.1 6.8 5.4 1.8 1 1 0 1 1 1 0 Serglycin CENP-Q PF13094.1 EMR63264.1 - 0.22 11.5 1.3 0.29 11.1 0.9 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Ank_2 PF12796.2 EMR63265.1 - 1e-12 48.2 0.1 6.1e-05 23.2 0.0 3.4 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) NACHT PF05729.7 EMR63265.1 - 6.2e-11 42.2 0.0 1.8e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.1 EMR63265.1 - 1.5e-10 41.2 0.3 0.0053 17.2 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR63265.1 - 3.5e-10 39.1 0.2 0.89 9.9 0.0 6.2 6 0 0 6 6 5 2 Ankyrin repeat AAA_22 PF13401.1 EMR63265.1 - 6.1e-06 26.4 0.0 0.00033 20.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EMR63265.1 - 3.3e-05 23.9 0.0 0.00011 22.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Ank PF00023.25 EMR63265.1 - 3.7e-05 23.3 0.1 1.1 9.1 0.0 5.3 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 EMR63265.1 - 5.6e-05 23.2 0.4 0.61 10.4 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) AAA_10 PF12846.2 EMR63265.1 - 0.0056 16.1 0.1 0.098 12.0 0.0 2.6 2 1 0 3 3 3 1 AAA-like domain TrwB_AAD_bind PF10412.4 EMR63265.1 - 0.0097 14.5 0.0 0.18 10.3 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 EMR63265.1 - 0.01 15.3 0.0 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.12 EMR63265.1 - 0.014 15.2 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 Arch_ATPase PF01637.13 EMR63265.1 - 0.016 14.9 0.0 0.049 13.3 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase SNF2_N PF00176.18 EMR63265.1 - 0.021 13.6 0.0 0.029 13.1 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 EMR63265.1 - 0.054 13.3 0.1 0.25 11.1 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EMR63265.1 - 0.066 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DAP3 PF10236.4 EMR63265.1 - 0.092 11.6 0.0 0.7 8.7 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Aldo_ket_red PF00248.16 EMR63266.1 - 1.8e-27 95.9 0.0 2.2e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family AAA PF00004.24 EMR63267.1 - 1.9e-20 73.3 0.0 5.1e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EMR63267.1 - 9.1e-05 22.4 0.0 0.00032 20.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EMR63267.1 - 0.00016 21.7 0.3 0.015 15.4 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.1 EMR63267.1 - 0.00047 20.0 0.0 0.0059 16.5 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMR63267.1 - 0.00097 18.8 0.0 0.0043 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMR63267.1 - 0.0021 18.0 0.2 0.0021 18.0 0.1 2.7 3 1 0 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.21 EMR63267.1 - 0.006 16.0 0.2 0.18 11.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 EMR63267.1 - 0.0064 16.2 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EMR63267.1 - 0.021 14.2 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 EMR63267.1 - 0.024 14.4 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EMR63267.1 - 0.029 14.1 3.2 0.23 11.2 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EMR63267.1 - 0.059 13.6 0.0 0.059 13.6 0.0 3.2 3 1 0 3 3 2 0 AAA domain AAA_25 PF13481.1 EMR63267.1 - 0.063 12.6 0.2 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 EMR63267.1 - 0.08 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_17 PF13207.1 EMR63267.1 - 0.13 13.1 0.1 0.13 13.1 0.0 3.2 3 3 0 3 3 3 0 AAA domain ArgK PF03308.11 EMR63267.1 - 0.15 10.7 1.5 0.37 9.5 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_11 PF13086.1 EMR63267.1 - 0.16 11.5 5.3 0.17 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Striatin PF08232.7 EMR63267.1 - 3.3 8.0 13.2 0.62 10.3 6.1 2.1 2 0 0 2 2 1 0 Striatin family Cyt-b5 PF00173.23 EMR63269.1 - 2.4e-19 68.8 0.3 9.5e-19 66.9 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EMR63269.1 - 1.9e-07 31.5 27.2 2.4e-07 31.1 17.5 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EMR63269.1 - 0.024 14.6 0.1 0.068 13.1 0.1 1.7 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region DUF1996 PF09362.5 EMR63270.1 - 9.1e-92 306.9 1.6 1.1e-91 306.6 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SGT1 PF07093.6 EMR63271.1 - 5e-61 206.8 46.6 3.5e-36 124.7 23.0 3.6 1 1 2 3 3 3 2 SGT1 protein AAA PF00004.24 EMR63271.1 - 1.1e-36 125.9 0.0 2.9e-36 124.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EMR63271.1 - 1.2e-06 28.2 0.0 4.7e-05 23.1 0.0 2.9 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EMR63271.1 - 2.2e-05 24.6 0.3 0.00031 20.8 0.1 2.8 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EMR63271.1 - 4.7e-05 23.4 0.7 0.0051 16.8 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EMR63271.1 - 5.3e-05 22.3 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EMR63271.1 - 0.00034 20.0 0.0 0.0018 17.6 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.8 EMR63271.1 - 0.0011 17.7 0.0 0.0023 16.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EMR63271.1 - 0.0037 16.9 0.0 0.011 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EMR63271.1 - 0.005 16.0 0.1 0.01 15.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EMR63271.1 - 0.0064 16.2 0.0 0.031 14.0 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EMR63271.1 - 0.016 15.0 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EMR63271.1 - 0.019 13.9 0.0 0.04 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 EMR63271.1 - 0.027 14.3 0.0 0.081 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EMR63271.1 - 0.028 13.9 0.0 0.084 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 EMR63271.1 - 0.049 12.8 0.2 5.6 6.1 0.0 3.1 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_17 PF13207.1 EMR63271.1 - 0.19 12.5 5.0 0.21 12.4 0.0 3.5 3 1 0 3 3 2 0 AAA domain Wzy_C PF04932.10 EMR63271.1 - 0.28 10.9 0.0 1.6 8.4 0.0 1.9 2 0 0 2 2 2 0 O-Antigen ligase AAA_28 PF13521.1 EMR63271.1 - 0.29 11.0 0.0 0.29 11.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.1 EMR63271.1 - 0.41 10.1 0.0 0.41 10.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EMR63271.1 - 0.53 9.6 4.6 0.28 10.5 0.1 2.8 3 1 0 4 4 3 0 AAA domain SMC_N PF02463.14 EMR63272.1 - 3.1e-21 75.6 16.1 3.9e-10 39.3 0.0 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMR63272.1 - 1.6e-09 38.4 36.8 1.6e-09 38.4 25.5 4.8 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EMR63272.1 - 5.3e-08 33.1 0.3 0.00011 22.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EMR63272.1 - 8.5e-06 25.0 6.4 8.5e-06 25.0 4.5 2.3 2 1 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 EMR63272.1 - 0.0001 22.1 0.0 0.0003 20.6 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EMR63272.1 - 0.0006 19.2 0.0 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_hinge PF06470.8 EMR63272.1 - 0.0011 18.8 0.1 0.0096 15.8 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain WEMBL PF05701.6 EMR63272.1 - 0.0016 17.0 6.2 0.0016 17.0 4.3 4.8 2 2 2 4 4 4 1 Weak chloroplast movement under blue light DUF869 PF05911.6 EMR63272.1 - 0.073 11.3 66.8 0.21 9.7 12.4 3.8 2 1 2 4 4 4 0 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 EMR63272.1 - 7.3 5.6 7.9 27 3.8 1.8 3.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein EthD PF07110.6 EMR63273.1 - 7.4e-10 39.6 0.0 9e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 EthD domain Pirin PF02678.11 EMR63274.1 - 2.2e-17 62.8 3.5 2.2e-16 59.6 2.4 2.4 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EMR63274.1 - 0.022 14.2 0.9 4.9 6.7 0.0 3.0 3 0 0 3 3 3 0 Cupin domain AraC_binding_2 PF14525.1 EMR63274.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AraC-binding-like domain Glyco_hydro_18 PF00704.23 EMR63275.1 - 9.3e-17 61.4 0.3 3.2e-16 59.7 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Hormone_4 PF00220.12 EMR63275.1 - 0.034 13.7 1.6 12 5.8 0.1 3.2 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain DNA_pol_phi PF04931.8 EMR63276.1 - 7.4 4.1 7.4 11 3.5 5.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi RNase_PH PF01138.16 EMR63278.1 - 4.7e-35 120.7 0.5 6.9e-35 120.2 0.3 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ADH_N PF08240.7 EMR63279.1 - 1.7e-27 95.3 2.1 3.8e-27 94.2 1.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR63279.1 - 5.4e-19 68.0 0.0 8.6e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR63279.1 - 0.00031 21.6 0.0 0.00056 20.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EMR63279.1 - 0.00076 19.1 0.4 0.0012 18.4 0.3 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase POR PF01558.13 EMR63279.1 - 0.0046 16.8 0.0 0.0065 16.3 0.0 1.2 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase 2-Hacid_dh_C PF02826.14 EMR63279.1 - 0.015 14.4 0.1 0.026 13.6 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding PF02629.14 EMR63279.1 - 0.1 13.1 0.4 0.26 11.8 0.1 1.7 2 0 0 2 2 2 0 CoA binding domain Scs3p PF10261.4 EMR63279.1 - 0.12 11.4 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM NIF PF03031.13 EMR63281.1 - 5.7e-38 130.0 0.0 9.5e-38 129.3 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase adh_short_C2 PF13561.1 EMR63282.1 - 8.9e-34 117.3 0.2 1.1e-33 116.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR63282.1 - 3.2e-27 95.5 0.4 4.3e-27 95.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR63282.1 - 2.1e-11 43.8 0.2 4.7e-11 42.6 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EMR63282.1 - 2.4e-06 27.1 0.2 5.7e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR63282.1 - 0.00055 19.9 0.3 0.0012 18.8 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EMR63282.1 - 0.0038 16.1 0.3 0.0052 15.7 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EMR63282.1 - 0.011 14.6 0.1 0.023 13.5 0.1 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EMR63282.1 - 0.054 13.2 0.9 0.054 13.2 0.6 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 EMR63282.1 - 0.083 11.5 0.2 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF605 PF04652.11 EMR63283.1 - 1.9e-70 238.1 0.8 2.3e-70 237.9 0.5 1.0 1 0 0 1 1 1 1 Vta1 like DUF812 PF05667.6 EMR63283.1 - 0.029 12.8 0.7 0.038 12.5 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Thioredoxin PF00085.15 EMR63284.1 - 4.6e-32 109.7 0.2 5.4e-25 87.0 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EMR63284.1 - 1.1e-09 38.3 0.0 4.9e-06 26.4 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EMR63284.1 - 2.2e-06 27.8 6.4 0.0017 18.5 0.1 3.3 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMR63284.1 - 2.6e-06 27.4 0.2 0.0051 16.9 0.0 3.6 3 2 0 3 3 3 2 Thioredoxin-like ERp29_N PF07912.8 EMR63284.1 - 0.0033 17.3 0.1 0.092 12.6 0.0 2.6 2 1 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_7 PF13899.1 EMR63284.1 - 0.0039 17.1 0.1 0.012 15.6 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EMR63284.1 - 0.034 13.7 0.0 0.12 11.9 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin NST1 PF13945.1 EMR63284.1 - 0.058 13.4 3.5 0.1 12.6 2.4 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator HyaE PF07449.6 EMR63284.1 - 0.13 12.2 0.0 2.6 8.0 0.0 2.8 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 EMR63284.1 - 0.36 10.6 4.2 0.7 9.7 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin domain Glyco_hydro_61 PF03443.9 EMR63285.1 - 3.1e-22 79.4 0.0 9.3e-21 74.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase PF00069.20 EMR63286.1 - 2.2e-53 181.0 0.0 3.2e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR63286.1 - 1.1e-24 86.9 0.0 1.5e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR63286.1 - 4.9e-07 28.9 0.0 7.2e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMR63286.1 - 0.014 14.4 0.0 0.034 13.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMR63286.1 - 0.027 14.1 0.1 0.29 10.8 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family RGS PF00615.14 EMR63287.1 - 3.9e-12 46.3 0.0 6e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain GST_C_2 PF13410.1 EMR63289.1 - 1.7e-09 37.3 0.9 3.8e-09 36.3 0.6 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR63289.1 - 3.5e-05 24.1 0.1 6.5e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMR63289.1 - 0.0043 17.0 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAD_binding_3 PF01494.14 EMR63290.1 - 1.1e-18 67.3 0.3 9.1e-15 54.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 EMR63290.1 - 1.5e-05 24.7 1.0 0.0056 16.4 0.1 3.4 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EMR63290.1 - 0.00012 22.0 0.2 0.00037 20.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR63290.1 - 0.014 14.3 0.8 0.22 10.4 0.4 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR63290.1 - 0.017 15.5 0.1 0.052 13.9 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EMR63290.1 - 0.028 13.2 0.0 0.098 11.4 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.9 EMR63290.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR63290.1 - 0.13 11.1 0.0 0.42 9.4 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Methyltransf_11 PF08241.7 EMR63291.1 - 1.2e-15 57.7 0.0 2.4e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR63291.1 - 3.8e-12 46.2 0.0 5.2e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR63291.1 - 8.4e-12 45.6 0.0 8.7e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR63291.1 - 1.4e-09 38.2 0.0 2.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR63291.1 - 1.6e-09 38.0 0.0 2.3e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR63291.1 - 1.7e-08 34.4 0.0 3.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR63291.1 - 3.4e-08 33.1 0.0 4.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EMR63291.1 - 0.00014 21.3 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EMR63291.1 - 0.00019 20.8 0.0 0.00029 20.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EMR63291.1 - 0.004 16.2 0.0 0.0052 15.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.11 EMR63291.1 - 0.0082 14.5 0.0 0.01 14.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.15 EMR63291.1 - 0.0086 15.1 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ank_4 PF13637.1 EMR63292.1 - 2.6e-13 50.1 0.1 5.8e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR63292.1 - 8.2e-12 44.9 0.4 3.6e-06 27.0 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMR63292.1 - 1.1e-11 44.9 0.0 3.4e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMR63292.1 - 2.5e-10 39.5 0.1 7.6e-05 22.5 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 EMR63292.1 - 4.4e-10 38.8 2.8 2.2e-05 24.0 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Oest_recep PF02159.10 EMR63292.1 - 5.9 7.0 15.0 0.36 10.9 5.9 2.3 1 1 1 2 2 2 0 Oestrogen receptor Atg14 PF10186.4 EMR63293.1 - 1.1e-19 70.5 0.1 3.6e-19 68.8 0.1 1.8 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EMR63293.1 - 0.28 9.8 2.9 0.43 9.1 2.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TauD PF02668.11 EMR63294.1 - 4.7e-41 141.1 0.0 7.8e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family WD40 PF00400.27 EMR63294.1 - 9.4e-16 57.0 4.1 9.1e-06 25.3 0.2 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Ax_dynein_light PF10211.4 EMR63294.1 - 0.079 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Glyco_hydro_18 PF00704.23 EMR63295.1 - 4.3e-17 62.5 7.0 3.6e-16 59.5 4.8 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 EMR63295.1 - 7.7e-09 35.0 12.4 2.3e-08 33.5 8.6 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain SMC_N PF02463.14 EMR63296.1 - 1.4e-07 30.9 0.0 9.4e-07 28.2 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.22 EMR63296.1 - 9.3e-05 22.7 0.2 0.27 11.5 0.0 2.9 1 1 0 2 2 2 2 ABC transporter SbcCD_C PF13558.1 EMR63296.1 - 0.0021 17.9 0.0 0.0053 16.6 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Myb_DNA-bind_3 PF12776.2 EMR63297.1 - 0.00042 20.8 0.6 0.00073 20.1 0.0 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain SET PF00856.23 EMR63298.1 - 6.3e-16 59.0 0.0 2.3e-14 54.0 0.0 2.2 1 1 0 1 1 1 1 SET domain UQ_con PF00179.21 EMR63299.1 - 3.1e-46 156.3 0.0 3.8e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMR63299.1 - 0.00014 21.6 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMR63299.1 - 0.00066 19.5 0.1 0.00083 19.2 0.1 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EMR63299.1 - 0.0049 16.5 0.1 0.0089 15.7 0.0 1.4 1 1 0 1 1 1 1 UEV domain MFS_1 PF07690.11 EMR63300.1 - 6.1e-29 100.8 29.3 6.1e-29 100.8 20.3 1.4 1 1 1 2 2 2 1 Major Facilitator Superfamily P22_AR_C PF10548.4 EMR63304.1 - 0.0027 17.5 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 P22AR C-terminal domain NPV_P10 PF05531.7 EMR63304.1 - 0.034 14.4 1.8 6.7 7.0 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Flagellin_C PF00700.16 EMR63304.1 - 0.034 14.2 0.3 9.7 6.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region DUF948 PF06103.6 EMR63304.1 - 0.077 12.8 1.7 1.7 8.5 0.1 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) V-SNARE PF05008.10 EMR63304.1 - 0.26 11.4 2.0 10 6.3 0.4 2.9 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Tet_JBP PF12851.2 EMR63305.1 - 4.5e-09 35.8 0.0 8.3e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Methyltransf_2 PF00891.13 EMR63309.1 - 2.9e-36 124.8 0.0 4e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EMR63309.1 - 1.7e-09 38.2 0.0 3.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR63309.1 - 1.8e-06 27.6 0.0 2.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR63309.1 - 9.8e-06 25.9 0.0 1.9e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR63309.1 - 0.0001 22.0 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR63309.1 - 0.00011 21.6 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 EMR63309.1 - 0.0018 17.5 0.0 0.0038 16.5 0.0 1.5 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Sigma70_r4 PF04545.11 EMR63309.1 - 0.0045 16.2 0.1 0.0091 15.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 DUF2413 PF10310.4 EMR63310.1 - 2.1e-138 461.8 0.0 5.3e-138 460.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 EMR63310.1 - 0.024 14.6 0.1 0.065 13.2 0.1 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Myc_N PF01056.13 EMR63310.1 - 4.9 6.2 12.0 0.061 12.4 2.9 1.8 2 0 0 2 2 2 0 Myc amino-terminal region PCI PF01399.22 EMR63312.1 - 0.0061 16.8 0.0 0.015 15.6 0.0 1.6 1 1 0 1 1 1 1 PCI domain Spt5_N PF11942.3 EMR63312.1 - 0.73 10.4 6.7 0.24 12.0 2.4 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal NUDIX PF00293.23 EMR63313.1 - 1.8e-10 40.5 0.0 2.1e-09 37.1 0.0 2.3 1 1 0 1 1 1 1 NUDIX domain GMC_oxred_N PF00732.14 EMR63314.1 - 8.6e-25 87.4 0.0 4.9e-24 85.0 0.0 2.2 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR63314.1 - 2.3e-18 66.8 0.1 4.9e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMR63314.1 - 4.9e-05 22.3 1.0 7.7e-05 21.7 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EMR63314.1 - 6e-05 23.2 0.0 0.029 14.4 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR63314.1 - 0.00016 20.2 0.4 0.00016 20.2 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EMR63314.1 - 0.00018 20.7 0.5 0.00027 20.0 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMR63314.1 - 0.00019 21.4 0.6 0.00048 20.0 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR63314.1 - 0.00023 21.1 0.8 0.0013 18.6 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR63314.1 - 0.00031 19.9 0.1 0.00062 18.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EMR63314.1 - 0.00036 19.5 0.9 0.0039 16.1 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EMR63314.1 - 0.0026 16.9 1.5 0.0065 15.5 1.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMR63314.1 - 0.0064 15.4 0.1 0.01 14.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 EMR63314.1 - 0.028 13.3 0.5 0.043 12.6 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Bd3614_N PF14442.1 EMR63314.1 - 6.1 6.8 8.0 1.2 9.1 2.7 1.9 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Ribosomal_L14 PF00238.14 EMR63316.1 - 1e-32 112.4 0.0 1.2e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF3317 PF11779.3 EMR63317.1 - 3e-14 52.1 1.7 3.8e-14 51.8 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) UPRTase PF14681.1 EMR63319.1 - 9.4e-37 126.2 0.6 1.4e-36 125.6 0.1 1.5 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase HAD PF12710.2 EMR63319.1 - 0.0001 22.5 0.0 0.00042 20.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.1 EMR63319.1 - 0.00051 20.8 0.1 0.0014 19.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain Pribosyltran PF00156.22 EMR63319.1 - 0.0028 17.3 0.1 0.051 13.2 0.1 2.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain ArgK PF03308.11 EMR63319.1 - 0.008 14.9 0.0 0.019 13.7 0.0 1.6 2 0 0 2 2 2 1 ArgK protein KAP_NTPase PF07693.9 EMR63319.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_14 PF13173.1 EMR63319.1 - 0.021 14.7 0.2 0.11 12.4 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 EMR63319.1 - 0.043 14.1 0.0 0.13 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EMR63319.1 - 0.072 11.9 0.0 0.2 10.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.1 EMR63319.1 - 0.077 13.1 0.0 3.4 7.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EMR63319.1 - 0.08 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Hydrolase_3 PF08282.7 EMR63319.1 - 0.11 12.1 0.0 0.58 9.6 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase AAA PF00004.24 EMR63319.1 - 0.11 12.6 0.1 1.2 9.3 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.10 EMR63319.1 - 0.22 10.1 0.0 0.44 9.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein Kinesin PF00225.18 EMR63320.1 - 6e-115 383.5 0.0 8.8e-115 382.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL14 PF03580.9 EMR63320.1 - 0.0053 16.5 3.5 0.012 15.3 2.4 1.5 1 0 0 1 1 1 1 Herpesvirus UL14-like protein DUF1397 PF07165.6 EMR63320.1 - 0.053 12.7 1.5 0.12 11.5 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) zf-C2H2 PF00096.21 EMR63321.1 - 1.9e-06 27.8 3.4 0.007 16.6 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR63321.1 - 0.00027 21.0 1.6 0.052 13.8 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMR63321.1 - 0.037 14.1 3.3 5.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EMR63321.1 - 0.25 11.4 2.1 2.7 8.2 0.7 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EMR63321.1 - 0.83 9.8 3.7 3.1 7.9 0.8 2.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DEAD PF00270.24 EMR63323.1 - 2.4e-42 144.2 0.0 1.2e-41 142.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR63323.1 - 1.3e-19 69.8 0.2 3e-19 68.6 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR63323.1 - 8.1e-05 22.5 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMR63323.1 - 0.00093 18.0 0.0 0.0017 17.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 EMR63323.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.4 1 1 0 1 1 1 0 SecA DEAD-like domain Ceramidase PF05875.7 EMR63324.1 - 1.6e-51 174.9 0.0 1.9e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Ceramidase WSC PF01822.14 EMR63325.1 - 4.4e-13 48.9 9.5 4.4e-13 48.9 6.6 2.0 2 0 0 2 2 2 1 WSC domain Abhydrolase_5 PF12695.2 EMR63325.1 - 1.4e-05 24.8 0.2 4.9e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR63325.1 - 0.001 18.9 0.1 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EMR63325.1 - 0.084 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) NmrA PF05368.8 EMR63326.1 - 2.2e-11 43.4 0.0 3.2e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR63326.1 - 4.7e-10 39.7 0.3 7.4e-10 39.1 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR63326.1 - 0.00044 19.7 0.2 0.00072 19.0 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EMR63326.1 - 0.00096 19.0 0.2 0.0022 17.9 0.1 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 EMR63326.1 - 0.012 15.2 0.2 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 EMR63326.1 - 0.017 13.8 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EMR63326.1 - 0.017 15.5 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.18 EMR63326.1 - 0.039 13.7 0.6 0.062 13.1 0.4 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EMR63326.1 - 0.069 13.4 0.2 0.14 12.4 0.1 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Malic_M PF03949.10 EMR63327.1 - 7.7e-82 274.6 0.1 9.7e-82 274.3 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EMR63327.1 - 2.4e-61 206.5 0.0 4.2e-61 205.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain AlaDh_PNT_C PF01262.16 EMR63327.1 - 0.021 14.4 0.2 0.036 13.6 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4484 PF14831.1 EMR63328.1 - 0.023 14.8 4.4 0.036 14.1 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) MFMR PF07777.6 EMR63328.1 - 0.11 12.3 3.2 0.19 11.6 2.2 1.3 1 0 0 1 1 1 0 G-box binding protein MFMR GLE1 PF07817.8 EMR63328.1 - 0.18 10.7 0.3 0.27 10.1 0.2 1.2 1 0 0 1 1 1 0 GLE1-like protein PI3K_1B_p101 PF10486.4 EMR63328.1 - 0.4 8.1 4.0 0.51 7.8 2.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nop14 PF04147.7 EMR63328.1 - 1.1 7.1 10.4 1.5 6.6 7.2 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 EMR63328.1 - 1.6 8.2 6.2 2.3 7.8 3.8 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.9 EMR63328.1 - 2.6 5.9 13.6 3.5 5.5 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 EMR63328.1 - 7.6 4.1 12.4 10 3.7 8.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.4 EMR63328.1 - 9.9 4.7 15.4 13 4.3 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TauD PF02668.11 EMR63329.1 - 8.8e-15 55.0 0.4 1.4e-14 54.3 0.3 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pkinase PF00069.20 EMR63330.1 - 2.5e-68 230.0 0.0 4.1e-68 229.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR63330.1 - 4.2e-31 107.9 0.0 2e-29 102.4 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR63330.1 - 0.00014 20.9 0.3 0.29 10.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EMR63330.1 - 0.065 12.9 0.0 0.82 9.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EMR63330.1 - 0.13 11.0 0.2 0.2 10.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase JAB PF01398.16 EMR63331.1 - 9.6e-35 118.7 0.0 1.8e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EMR63331.1 - 9.9e-27 93.3 0.8 9.9e-27 93.3 0.5 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EMR63331.1 - 9.6e-09 34.7 0.0 1.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.14 EMR63332.1 - 4e-79 266.1 0.2 7.3e-79 265.2 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain Hce2 PF14856.1 EMR63333.1 - 0.038 13.8 2.2 0.063 13.1 1.3 1.5 1 1 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor Eclosion PF04736.7 EMR63333.1 - 0.096 12.1 2.7 0.9 9.0 0.0 2.9 3 0 0 3 3 3 0 Eclosion hormone Ribosomal_L31e PF01198.14 EMR63334.1 - 5e-39 131.8 1.9 6.7e-39 131.4 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e M20_dimer PF07687.9 EMR63334.1 - 0.082 12.6 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Peptidase dimerisation domain DUF4188 PF13826.1 EMR63335.1 - 1.3e-31 109.1 0.0 1.9e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 EMR63335.1 - 0.076 12.0 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase DHDPS PF00701.17 EMR63337.1 - 3e-42 144.2 0.0 3.4e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family alpha-hel2 PF14456.1 EMR63338.1 - 0.022 13.5 0.3 0.027 13.2 0.2 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 DUF1399 PF07173.7 EMR63339.1 - 3.9e-13 49.8 1.0 1.2e-12 48.2 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1399) DUF1045 PF06299.7 EMR63339.1 - 0.18 11.4 1.5 0.28 10.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) Peptidase_S10 PF00450.17 EMR63340.1 - 2.6e-79 267.3 0.2 4.3e-79 266.6 0.1 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase DUF2828 PF11443.3 EMR63341.1 - 9.3e-170 565.3 0.0 7.4e-168 559.0 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF2828) GCIP PF13324.1 EMR63341.1 - 0.085 12.0 3.4 0.15 11.2 2.4 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.7 EMR63341.1 - 0.51 8.1 12.1 0.009 13.9 2.4 1.9 2 0 0 2 2 2 0 Nop14-like family Glyco_hydro_28 PF00295.12 EMR63343.1 - 3.1e-35 121.7 7.6 4.5e-35 121.1 5.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Lysozyme_like PF13702.1 EMR63344.1 - 0.0018 17.7 0.8 0.0052 16.2 0.5 1.7 1 1 0 1 1 1 1 Lysozyme-like SLT PF01464.15 EMR63344.1 - 0.028 13.9 1.1 0.12 11.8 0.8 2.0 1 1 0 1 1 1 0 Transglycosylase SLT domain APH PF01636.18 EMR63345.1 - 3.2e-08 33.6 0.1 9e-08 32.1 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMR63345.1 - 0.0003 20.4 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase CENP-T PF15511.1 EMR63345.1 - 0.013 14.7 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T GTP_cyclohydroI PF01227.17 EMR63346.1 - 1.1e-72 243.0 0.2 1.7e-72 242.4 0.1 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EMR63346.1 - 0.00052 19.9 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein OmpH PF03938.9 EMR63346.1 - 0.16 11.9 1.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SR-25 PF10500.4 EMR63346.1 - 0.2 11.1 20.4 0.28 10.6 14.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LysM PF01476.15 EMR63347.1 - 8.6e-12 44.7 0.0 0.0005 19.8 0.0 3.4 3 0 0 3 3 3 2 LysM domain PLRV_ORF5 PF01690.12 EMR63347.1 - 0.1 11.6 0.2 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Glyco_hydro_18 PF00704.23 EMR63348.1 - 3.8e-40 138.3 0.1 6.6e-40 137.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TAFII28 PF04719.9 EMR63349.1 - 2.4e-18 65.7 0.2 2.4e-17 62.4 0.1 2.1 1 1 0 1 1 1 1 hTAFII28-like protein conserved region tRNA-synt_2c PF01411.14 EMR63350.1 - 2.1e-210 699.7 2.3 2.2e-210 699.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EMR63350.1 - 7.9e-16 57.6 0.5 2.1e-15 56.3 0.3 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EMR63350.1 - 4e-05 23.2 0.9 0.00014 21.4 0.6 2.0 1 0 0 1 1 1 1 DHHA1 domain Methyltransf_28 PF02636.12 EMR63351.1 - 2.5e-38 131.9 0.0 5.6e-38 130.7 0.0 1.6 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 EMR63351.1 - 0.011 14.7 0.0 0.021 13.7 0.0 1.5 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 EMR63351.1 - 0.11 12.4 0.1 0.31 11.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PALP PF00291.20 EMR63352.1 - 2e-51 175.0 3.2 3.3e-51 174.3 2.2 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme BRF1 PF07741.8 EMR63352.1 - 0.0061 16.7 3.0 0.0061 16.7 2.1 2.3 2 1 0 2 2 2 1 Brf1-like TBP-binding domain DUF3824 PF12868.2 EMR63352.1 - 0.078 13.9 0.7 0.21 12.5 0.5 1.7 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) zf-ZPR1 PF03367.8 EMR63352.1 - 0.13 11.4 0.1 0.24 10.5 0.1 1.4 1 0 0 1 1 1 0 ZPR1 zinc-finger domain U1snRNP70_N PF12220.3 EMR63352.1 - 0.46 10.8 8.2 0.098 12.9 3.1 1.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2956 PF11169.3 EMR63352.1 - 0.62 10.0 10.3 0.55 10.2 5.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) NARP1 PF12569.3 EMR63352.1 - 3.4 6.3 7.6 5.2 5.7 5.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TFIIS_M PF07500.9 EMR63353.1 - 1.2e-26 93.0 1.2 2.5e-26 91.9 0.9 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EMR63353.1 - 4.3e-18 64.6 8.2 4.3e-18 64.6 5.7 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EMR63353.1 - 3.3e-10 39.2 0.2 7e-10 38.2 0.1 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF1019 PF06254.6 EMR63353.1 - 0.0069 16.5 0.9 0.013 15.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1019) Borrelia_REV PF03978.8 EMR63353.1 - 0.051 13.2 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Elf1 PF05129.8 EMR63353.1 - 0.069 12.8 3.0 0.15 11.7 2.0 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Ten1 PF12658.2 EMR63353.1 - 0.088 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Telomere capping, CST complex subunit Evr1_Alr PF04777.8 EMR63353.1 - 0.16 11.8 4.6 1 9.2 1.4 2.5 1 1 1 2 2 2 0 Erv1 / Alr family Sgf11 PF08209.6 EMR63353.1 - 0.31 10.3 6.4 4.9 6.5 0.2 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) 4HBT_2 PF13279.1 EMR63354.1 - 2.9e-08 34.1 0.0 4.4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily ELO PF01151.13 EMR63356.1 - 2.4e-63 213.7 14.7 2.9e-63 213.5 10.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ABC_tran PF00005.22 EMR63358.1 - 1.8e-40 138.4 0.0 8.6e-21 74.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMR63358.1 - 7e-21 74.8 11.4 7e-21 74.8 7.9 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.1 EMR63358.1 - 8.4e-15 55.4 0.1 0.0049 16.8 0.0 4.3 3 1 0 4 4 4 4 AAA domain AAA_16 PF13191.1 EMR63358.1 - 2.5e-08 34.1 0.9 6.7e-05 22.9 0.4 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EMR63358.1 - 8.9e-08 31.5 0.4 0.0089 15.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EMR63358.1 - 1.2e-07 31.1 5.9 0.1 11.8 0.2 5.1 4 2 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EMR63358.1 - 2.4e-07 31.5 0.0 0.035 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EMR63358.1 - 2.8e-06 27.2 0.0 0.023 14.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EMR63358.1 - 4e-06 26.3 0.1 0.014 14.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMR63358.1 - 8.2e-06 25.9 0.0 0.083 13.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EMR63358.1 - 1.6e-05 25.1 0.0 0.052 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EMR63358.1 - 2.8e-05 23.1 0.0 0.22 10.4 0.0 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein DUF258 PF03193.11 EMR63358.1 - 6.6e-05 22.1 0.2 0.28 10.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 EMR63358.1 - 0.00015 21.4 0.4 0.26 10.9 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EMR63358.1 - 0.00023 21.6 0.0 0.17 12.3 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 EMR63358.1 - 0.00039 19.9 0.1 0.2 11.1 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 EMR63358.1 - 0.00041 19.8 0.0 0.35 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain MMR_HSR1 PF01926.18 EMR63358.1 - 0.0006 19.7 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMR63358.1 - 0.00062 19.6 0.1 0.087 12.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.1 EMR63358.1 - 0.00071 19.9 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain ATP_bind_1 PF03029.12 EMR63358.1 - 0.0041 16.7 0.6 0.46 9.9 0.1 3.1 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 EMR63358.1 - 0.024 14.5 0.0 13 5.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 EMR63358.1 - 0.087 12.3 0.5 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 EMR63358.1 - 0.14 11.9 0.6 0.26 11.0 0.0 1.6 2 0 0 2 2 1 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 EMR63358.1 - 0.19 11.8 0.0 17 5.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Septin PF00735.13 EMR63358.1 - 0.3 10.0 0.0 16 4.3 0.0 2.2 2 0 0 2 2 2 0 Septin ABC_ATPase PF09818.4 EMR63358.1 - 2.9 6.3 4.3 7.3 5.0 0.0 2.9 4 0 0 4 4 4 0 Predicted ATPase of the ABC class EamA PF00892.15 EMR63359.1 - 4.7e-13 49.2 6.6 6.4e-09 35.9 1.3 2.7 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EMR63359.1 - 6.8e-05 23.0 13.6 0.029 14.5 0.1 3.1 3 1 0 3 3 3 2 Multidrug resistance efflux transporter DUF4203 PF13886.1 EMR63359.1 - 0.013 14.9 0.1 0.013 14.9 0.1 2.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4203) RII_binding_1 PF10522.4 EMR63359.1 - 0.22 11.7 3.3 0.53 10.6 2.3 1.7 1 0 0 1 1 1 0 RII binding domain MFS_1 PF07690.11 EMR63360.1 - 3e-06 26.2 12.8 0.00052 18.8 0.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S10 PF00450.17 EMR63361.1 - 1.3e-36 126.7 0.0 3e-35 122.1 0.0 2.3 1 1 0 1 1 1 1 Serine carboxypeptidase APH PF01636.18 EMR63361.1 - 3.9e-10 39.8 0.1 1.4e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMR63361.1 - 6.3e-05 22.2 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EMR63361.1 - 0.00066 19.3 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF3328 PF11807.3 EMR63363.1 - 8.1e-21 74.7 0.1 9.3e-21 74.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Polyketide_cyc PF03364.15 EMR63364.1 - 1.8e-07 31.2 0.4 9.9 6.1 0.0 5.8 1 1 4 5 5 5 3 Polyketide cyclase / dehydrase and lipid transport Alpha-2-MRAP_N PF06400.6 EMR63364.1 - 4e-07 29.7 0.2 15 5.2 0.0 5.8 1 1 5 6 6 6 2 Alpha-2-macroglobulin RAP, N-terminal domain RHS_repeat PF05593.9 EMR63364.1 - 0.00058 19.9 10.2 52 4.1 0.0 6.1 6 0 0 6 6 6 0 RHS Repeat TetR_C_6 PF13977.1 EMR63364.1 - 0.0022 17.9 0.1 20 5.2 0.0 4.5 1 1 5 6 6 6 1 Bacterial transcriptional repressor CAP_assoc_N PF14504.1 EMR63364.1 - 0.015 15.0 0.3 5.7 6.6 0.0 3.7 2 2 4 6 6 6 0 CAP-associated N-terminal Gemini_AC4_5_2 PF08464.5 EMR63364.1 - 0.053 13.2 1.3 4.3e+02 0.7 0.0 5.3 6 0 0 6 6 6 0 Geminivirus AC4/5 conserved region DUF3328 PF11807.3 EMR63365.1 - 4.3e-29 101.7 0.1 5.6e-29 101.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 EMR63366.1 - 6.3e-18 64.6 58.0 2.6e-11 42.8 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1446 PF07287.6 EMR63368.1 - 1.2e-119 399.0 0.1 1.4e-119 398.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Aldo_ket_red PF00248.16 EMR63370.1 - 6.8e-23 80.8 0.0 3.5e-22 78.5 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family DUF964 PF06133.6 EMR63370.1 - 0.071 13.1 0.2 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF964) RBD-FIP PF09457.5 EMR63370.1 - 0.17 11.7 3.1 1.4 8.7 0.7 2.5 2 0 0 2 2 2 0 FIP domain Beta-lactamase PF00144.19 EMR63372.1 - 2.6e-34 118.7 0.1 3.8e-34 118.2 0.1 1.3 1 1 0 1 1 1 1 Beta-lactamase Nrap PF03813.9 EMR63374.1 - 1.5e-299 995.9 0.0 1.8e-299 995.6 0.0 1.0 1 0 0 1 1 1 1 Nrap protein MFS_1 PF07690.11 EMR63375.1 - 2e-35 122.1 23.8 3e-35 121.5 16.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cu_bind_like PF02298.12 EMR63376.1 - 0.26 11.1 1.0 0.96 9.2 0.7 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain PH PF00169.24 EMR63377.1 - 2.4e-10 40.5 0.0 5.6e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 EMR63377.1 - 0.006 14.1 0.5 0.0091 13.5 0.3 1.2 1 0 0 1 1 1 1 Prominin Acyl_CoA_thio PF02551.10 EMR63377.1 - 0.051 13.1 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Acyl-CoA thioesterase tRNA-synt_2b PF00587.20 EMR63378.1 - 3.3e-45 153.7 0.3 5.7e-45 152.9 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMR63378.1 - 4.3e-18 65.0 0.2 1e-17 63.8 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EMR63378.1 - 5.4e-12 45.3 0.0 1.1e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EMR63378.1 - 1.1e-10 41.1 0.0 2.5e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain AMP-binding PF00501.23 EMR63379.1 - 7.7e-67 225.4 0.1 6.5e-48 163.1 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme PP-binding PF00550.20 EMR63379.1 - 4.3e-11 42.8 0.0 1e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.15 EMR63379.1 - 9.3e-10 37.8 0.0 1.6e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.1 EMR63379.1 - 0.0067 17.3 0.0 0.018 15.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EMR63380.1 - 5.6e-15 55.4 0.0 8.5e-15 54.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR63380.1 - 5.8e-12 44.9 0.0 8.6e-12 44.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMR63380.1 - 5.4e-11 42.8 0.2 1e-10 41.9 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMR63380.1 - 1.7e-10 41.0 1.7 2.9e-10 40.3 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR63380.1 - 3.3e-08 33.3 0.1 6.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EMR63380.1 - 4.1e-08 32.7 0.1 5.7e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EMR63380.1 - 8.3e-08 31.4 0.0 1.5e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EMR63380.1 - 3.7e-05 22.7 0.0 5.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EMR63380.1 - 0.019 13.8 0.1 0.28 10.0 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Semialdhyde_dh PF01118.19 EMR63380.1 - 0.028 14.7 0.0 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMR63380.1 - 0.078 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_5 PF12695.2 EMR63381.1 - 3.7e-08 33.2 0.0 6.2e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR63381.1 - 9.4e-05 22.3 0.1 0.00079 19.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR63381.1 - 0.0017 17.9 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 EMR63381.1 - 0.0049 16.1 1.8 0.0049 16.1 1.3 2.0 2 1 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.8 EMR63381.1 - 0.028 14.0 0.0 0.14 11.7 0.0 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMR63381.1 - 0.044 13.0 0.1 0.43 9.7 0.0 2.2 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EMR63381.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF1100 PF06500.6 EMR63381.1 - 0.099 11.1 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF3328 PF11807.3 EMR63382.1 - 6e-43 147.0 1.0 7.7e-43 146.6 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TPP_enzyme_N PF02776.13 EMR63383.1 - 9.2e-34 116.4 0.1 1.5e-33 115.7 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMR63383.1 - 9.9e-28 96.5 0.0 2.1e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EMR63383.1 - 2.3e-15 56.4 0.1 7.9e-15 54.7 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain OCC1 PF15506.1 EMR63383.1 - 0.033 14.0 1.5 1.2 9.0 0.3 2.8 2 0 0 2 2 2 0 OCC1 family E1-N PF14463.1 EMR63383.1 - 0.038 13.6 0.1 0.13 11.8 0.1 2.0 1 0 0 1 1 1 0 E1 N-terminal domain Med3 PF11593.3 EMR63384.1 - 0.25 10.5 4.8 0.3 10.2 3.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SKG6 PF08693.5 EMR63384.1 - 0.4 10.0 4.2 0.16 11.3 0.9 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Gar1 PF04410.9 EMR63385.1 - 3.7e-40 136.8 0.2 3.7e-40 136.8 0.1 2.2 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region Arylsulfotran_2 PF14269.1 EMR63386.1 - 1.3e-42 146.0 1.0 1.8e-42 145.5 0.7 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EMR63386.1 - 7.9e-16 57.6 0.2 8.4e-15 54.2 0.1 2.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Peptidase_C14 PF00656.17 EMR63387.1 - 3.8e-73 246.2 0.0 4.5e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Caspase domain DUF3340 PF11818.3 EMR63387.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Raptor_N PF14538.1 EMR63387.1 - 0.12 12.1 0.1 0.61 9.9 0.0 2.1 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain TLD PF07534.11 EMR63388.1 - 3.4e-24 85.4 0.0 1e-12 48.2 0.0 2.2 2 0 0 2 2 2 2 TLD Lamp PF01299.12 EMR63388.1 - 0.02 14.0 0.6 0.035 13.2 0.4 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Transglut_core2 PF13369.1 EMR63390.1 - 2.8e-12 46.3 0.0 5.6e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.6 EMR63390.1 - 2.6e-11 43.3 0.0 5.6e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box PF00646.28 EMR63390.1 - 0.11 12.1 1.7 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 F-box domain AAA_13 PF13166.1 EMR63390.1 - 0.16 10.4 0.0 0.21 9.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain EI24 PF07264.6 EMR63391.1 - 8.4e-08 31.9 3.1 1.7e-07 30.9 1.6 1.7 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) ADH_N PF08240.7 EMR63392.1 - 2.8e-10 39.9 0.0 7.3e-10 38.5 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR63392.1 - 1.1e-08 34.6 0.1 2.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Evr1_Alr PF04777.8 EMR63393.1 - 2e-29 101.3 1.5 2.4e-29 101.0 0.2 1.6 2 0 0 2 2 2 1 Erv1 / Alr family Bd3614-deam PF14439.1 EMR63393.1 - 0.013 15.3 0.2 0.1 12.4 0.0 2.1 2 1 0 2 2 2 0 Bd3614-like deaminase Plant_NMP1 PF06694.6 EMR63393.1 - 0.28 10.0 1.2 0.35 9.7 0.8 1.1 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) MFS_1 PF07690.11 EMR63394.1 - 2.8e-09 36.1 3.7 3.4e-09 35.8 2.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_43 PF04616.9 EMR63395.1 - 1.5e-09 37.4 9.9 1.5e-05 24.2 2.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 DUF3328 PF11807.3 EMR63396.1 - 5.2e-50 170.1 0.7 6.6e-50 169.7 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FATC PF02260.15 EMR63396.1 - 0.017 14.5 0.4 0.032 13.6 0.3 1.4 1 0 0 1 1 1 0 FATC domain CoA_trans PF01144.18 EMR63397.1 - 2.7e-98 327.4 0.6 2.8e-60 203.1 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EMR63397.1 - 0.0019 17.8 0.0 0.0078 15.8 0.0 1.8 1 1 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain adh_short_C2 PF13561.1 EMR63398.1 - 1.6e-17 64.1 0.0 1.9e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR63398.1 - 8.9e-10 38.7 0.5 2.3e-09 37.4 0.2 1.9 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR63398.1 - 3.1e-05 23.7 0.1 0.00037 20.2 0.0 2.1 2 0 0 2 2 2 1 KR domain Ribophorin_II PF05817.9 EMR63398.1 - 0.039 12.1 0.1 0.061 11.5 0.1 1.3 1 1 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II DFP PF04127.10 EMR63398.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Abhydrolase_6 PF12697.2 EMR63399.1 - 7e-12 45.7 0.2 1.1e-11 45.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR63399.1 - 8.2e-07 28.8 0.3 2.4e-06 27.3 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR63399.1 - 0.019 14.5 0.1 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0029 PF01205.14 EMR63400.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 Microtub_assoc PF07989.6 EMR63401.1 - 1.1e-27 95.6 4.3 1.1e-27 95.6 3.0 12.6 8 4 5 13 13 12 2 Microtubule associated PACT_coil_coil PF10495.4 EMR63401.1 - 5.3e-09 35.8 1.5 1.2e-07 31.5 1.0 2.9 1 1 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein MscS_porin PF12795.2 EMR63401.1 - 5.9e-07 29.0 195.6 0.0003 20.2 12.9 8.4 1 1 6 7 7 7 4 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 EMR63401.1 - 2e-06 26.6 133.5 0.02 13.3 18.0 6.2 1 1 4 6 6 6 6 AAA domain Reo_sigmaC PF04582.7 EMR63401.1 - 0.00032 20.0 55.2 0.14 11.3 2.0 7.8 1 1 8 9 9 9 7 Reovirus sigma C capsid protein IncA PF04156.9 EMR63401.1 - 0.00055 19.5 218.5 0.0012 18.4 18.3 10.7 1 1 9 10 10 9 5 IncA protein CENP-F_leu_zip PF10473.4 EMR63401.1 - 0.00077 19.3 17.3 0.00077 19.3 12.0 11.1 2 2 9 11 11 11 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 EMR63401.1 - 0.00083 19.2 214.2 0.044 13.6 25.8 11.1 1 1 12 14 14 14 6 Tropomyosin like ATG16 PF08614.6 EMR63401.1 - 0.0014 18.4 16.4 0.0014 18.4 11.4 12.2 1 1 11 12 12 12 6 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 EMR63401.1 - 0.0017 18.0 3.5 0.0017 18.0 2.4 11.8 3 2 8 11 11 11 6 TPR/MLP1/MLP2-like protein Laminin_II PF06009.7 EMR63401.1 - 0.0044 16.7 115.4 0.0086 15.8 4.2 10.6 3 2 8 12 12 12 6 Laminin Domain II Spc7 PF08317.6 EMR63401.1 - 0.71 8.4 162.1 0.0056 15.3 16.4 8.2 1 1 7 8 8 8 0 Spc7 kinetochore protein Halo_GVPC PF05465.8 EMR63401.1 - 1.5 8.8 11.7 21 5.1 0.0 6.0 6 0 0 6 6 6 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF2013 PF09431.5 EMR63402.1 - 1e-50 171.1 2.7 2.4e-50 169.9 1.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Clr5 PF14420.1 EMR63403.1 - 6.3e-20 70.8 0.8 1.2e-19 69.9 0.6 1.5 1 0 0 1 1 1 1 Clr5 domain Glyco_hydro_cc PF11790.3 EMR63404.1 - 1.5e-47 162.0 0.7 1.9e-47 161.7 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 EMR63404.1 - 0.031 13.0 0.1 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 PhyH PF05721.8 EMR63406.1 - 1.3e-10 41.7 0.1 2.8e-10 40.5 0.1 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.11 EMR63406.1 - 0.1 12.2 0.2 0.51 9.9 0.0 2.2 2 1 1 3 3 3 0 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_92 PF07971.7 EMR63407.1 - 2.5e-169 564.1 0.0 2.8e-169 563.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Pectate_lyase_3 PF12708.2 EMR63408.1 - 6.5e-84 281.5 22.5 9.3e-67 225.4 6.6 3.4 2 1 1 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EMR63408.1 - 2.4e-07 30.0 2.1 0.013 14.9 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Dynamin_N PF00350.18 EMR63410.1 - 1.8e-28 99.4 0.0 3.2e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EMR63410.1 - 4.6e-05 23.3 0.0 0.00015 21.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 EMR63410.1 - 0.00037 20.3 0.1 0.0092 15.8 0.0 2.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain Dynamin_M PF01031.15 EMR63410.1 - 0.001 17.9 0.2 0.014 14.2 0.0 2.5 3 0 0 3 3 3 1 Dynamin central region Miro PF08477.8 EMR63410.1 - 0.0061 17.0 0.0 0.021 15.3 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 EMR63410.1 - 0.028 14.3 0.1 0.25 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain JAB PF01398.16 EMR63411.1 - 3.1e-07 30.1 0.0 7.2e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EMR63411.1 - 0.00031 20.7 0.8 0.0041 17.1 0.4 2.7 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function Acp26Ab PF05777.7 EMR63411.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) Cupin_2 PF07883.6 EMR63412.1 - 6.9e-18 63.9 0.1 1.3e-17 63.0 0.1 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EMR63412.1 - 7.7e-07 28.8 0.1 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EMR63412.1 - 5.9e-06 25.7 0.0 7.3e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EMR63412.1 - 0.0001 21.9 0.0 0.00012 21.8 0.0 1.1 1 0 0 1 1 1 1 Cupin ARD PF03079.9 EMR63412.1 - 0.00028 20.8 0.4 0.00057 19.8 0.0 1.6 2 0 0 2 2 2 1 ARD/ARD' family Cupin_3 PF05899.7 EMR63412.1 - 0.00054 19.2 0.1 0.001 18.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) JmjC PF02373.17 EMR63412.1 - 0.0094 16.1 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.6 EMR63412.1 - 0.014 14.4 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) DUF2269 PF10027.4 EMR63413.1 - 0.001 18.8 0.2 0.0021 17.8 0.2 1.4 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) YWFCY PF14293.1 EMR63413.1 - 0.22 11.4 0.0 0.42 10.4 0.0 1.4 1 0 0 1 1 1 0 YWFCY protein DASH_Spc34 PF08657.5 EMR63413.1 - 0.4 10.2 8.6 0.13 11.9 1.2 2.2 2 0 0 2 2 2 0 DASH complex subunit Spc34 2-Hacid_dh_C PF02826.14 EMR63414.1 - 2.4e-40 137.5 0.0 4e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMR63414.1 - 3.7e-26 91.1 0.0 4.7e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Tmemb_14 PF03647.8 EMR63414.1 - 7.6e-19 67.9 4.8 1.6e-18 66.9 3.3 1.5 1 0 0 1 1 1 1 Transmembrane proteins 14C IlvN PF07991.7 EMR63414.1 - 0.016 14.5 0.0 0.15 11.3 0.0 2.4 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 EMR63414.1 - 0.022 14.5 0.5 0.088 12.6 0.4 1.8 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.12 EMR63414.1 - 0.055 13.9 0.1 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GRAM PF02893.15 EMR63415.1 - 1.8e-17 62.5 0.0 3.9e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 GRAM domain ADH_N PF08240.7 EMR63416.1 - 2.1e-25 88.6 1.7 4e-25 87.7 1.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR63416.1 - 5.8e-16 58.2 0.1 1.4e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 EMR63416.1 - 0.027 14.5 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMR63416.1 - 0.036 13.4 0.1 0.087 12.1 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EMR63416.1 - 0.051 13.2 0.3 0.08 12.5 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EMR63416.1 - 0.064 13.0 0.5 0.12 12.2 0.3 1.4 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.13 EMR63416.1 - 0.07 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.1 EMR63416.1 - 0.089 12.8 0.5 0.28 11.2 0.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR63416.1 - 0.09 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EMR63416.1 - 0.11 12.0 0.2 0.27 10.7 0.1 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CENP-Q PF13094.1 EMR63417.1 - 0.021 14.8 2.9 0.021 14.8 2.0 3.3 3 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Dor1 PF04124.7 EMR63417.1 - 2.3 6.6 5.8 0.88 7.9 0.2 2.5 3 0 0 3 3 3 0 Dor1-like family DUF972 PF06156.8 EMR63417.1 - 5.7 7.3 6.5 26 5.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) SMC_Nse1 PF07574.8 EMR63419.1 - 8.3e-35 120.2 0.0 1.1e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EMR63419.1 - 6.6e-12 45.2 11.5 1.1e-11 44.5 8.0 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 EMR63419.1 - 0.031 14.0 8.2 0.25 11.1 5.4 2.2 2 0 0 2 2 2 0 Ring finger domain DUF2161 PF09929.4 EMR63419.1 - 0.048 13.5 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2161) Nucleoplasmin PF03066.10 EMR63419.1 - 0.61 9.6 5.3 1 8.8 3.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin IBR PF01485.16 EMR63419.1 - 4.3 7.2 9.0 38 4.2 6.2 2.1 1 1 0 1 1 1 0 IBR domain Vps5 PF09325.5 EMR63420.1 - 3.4e-15 55.9 0.2 5e-15 55.4 0.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EMR63420.1 - 2.9e-08 33.4 0.0 5.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 PX domain Cyclin_N PF00134.18 EMR63421.1 - 0.049 13.2 0.0 0.2 11.2 0.0 2.0 1 1 0 1 1 1 0 Cyclin, N-terminal domain GST_N PF02798.15 EMR63422.1 - 2.3e-13 50.1 0.0 3.8e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMR63422.1 - 1e-06 28.6 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMR63422.1 - 1.8e-06 28.0 0.0 3.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR63422.1 - 2.1e-06 27.5 0.1 1.1e-05 25.2 0.1 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMR63422.1 - 6.1e-06 26.1 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR63422.1 - 0.0026 18.2 0.0 0.0086 16.5 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain EFG_II PF14492.1 EMR63423.1 - 7.8e-21 73.7 0.0 1.9e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU PF00009.22 EMR63423.1 - 1.1e-16 60.8 0.0 1.7e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EMR63423.1 - 1.6e-15 56.6 0.0 3.9e-14 52.2 0.0 2.6 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMR63423.1 - 4.2e-05 23.5 0.0 0.00015 21.7 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Kelch_5 PF13854.1 EMR63425.1 - 4.3e-18 64.8 8.5 2.2e-08 33.8 0.2 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 EMR63425.1 - 2.3e-11 43.2 7.0 0.026 14.2 0.0 6.0 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EMR63425.1 - 7.4e-11 41.9 12.6 0.00023 21.2 0.1 6.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EMR63425.1 - 4.7e-07 29.6 13.2 0.13 12.5 0.1 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 EMR63425.1 - 0.00029 20.2 9.7 0.16 11.5 0.1 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 EMR63425.1 - 0.00052 19.6 10.3 0.087 12.6 0.0 5.1 7 0 0 7 7 7 2 Kelch motif Zn-ribbon_8 PF09723.5 EMR63427.1 - 0.0036 17.2 2.4 1.2 9.1 0.3 2.6 2 0 0 2 2 2 2 Zinc ribbon domain zf-IS66 PF13005.2 EMR63427.1 - 0.019 14.9 1.5 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 DZR PF12773.2 EMR63427.1 - 0.071 12.9 0.8 6.6 6.6 0.3 2.5 2 0 0 2 2 2 0 Double zinc ribbon UPF0547 PF10571.4 EMR63427.1 - 4.5 7.0 7.9 8.7 6.1 0.1 3.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.1 EMR63427.1 - 5.3 6.3 6.8 2.7 7.3 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain UBA_3 PF09288.5 EMR63428.1 - 0.25 10.9 0.9 1.2 8.8 0.0 2.5 4 0 0 4 4 4 0 Fungal ubiquitin-associated domain CUE PF02845.11 EMR63429.1 - 2.5e-11 42.8 0.0 4.2e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.3 EMR63429.1 - 0.014 15.0 0.0 0.047 13.3 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 UBA PF00627.26 EMR63429.1 - 0.032 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain OPT PF03169.10 EMR63430.1 - 1.4e-169 565.4 50.2 1.6e-169 565.2 34.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FlgM PF04316.8 EMR63430.1 - 0.00042 20.1 1.4 0.00084 19.2 1.0 1.5 1 0 0 1 1 1 1 Anti-sigma-28 factor, FlgM AMP-binding PF00501.23 EMR63431.1 - 5e-36 123.9 0.0 6.4e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme TFR_dimer PF04253.10 EMR63432.1 - 4.5e-19 68.2 0.0 7.1e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EMR63432.1 - 8.9e-11 41.8 0.0 4.4e-10 39.5 0.0 2.1 1 1 1 2 2 2 1 Peptidase family M28 PA PF02225.17 EMR63432.1 - 3.2e-06 26.7 0.2 7.7e-06 25.5 0.2 1.6 1 0 0 1 1 1 1 PA domain Myosin_tail_1 PF01576.14 EMR63433.1 - 0.00037 18.3 5.7 0.00047 18.0 3.9 1.0 1 0 0 1 1 1 1 Myosin tail TPR_MLP1_2 PF07926.7 EMR63433.1 - 0.00071 19.3 5.2 0.0011 18.6 3.6 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein ERM PF00769.14 EMR63433.1 - 0.0022 17.5 6.5 0.0027 17.2 4.5 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family AAA_13 PF13166.1 EMR63433.1 - 0.0023 16.4 0.5 0.0027 16.2 0.4 1.0 1 0 0 1 1 1 1 AAA domain Filament PF00038.16 EMR63433.1 - 0.0044 16.5 2.9 0.0055 16.2 2.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein DUF342 PF03961.8 EMR63433.1 - 0.0065 14.9 0.2 0.0067 14.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 EMR63433.1 - 0.0066 16.4 2.7 0.022 14.7 0.7 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Muted PF14942.1 EMR63433.1 - 0.0087 15.9 1.8 0.012 15.4 1.2 1.2 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein DUF972 PF06156.8 EMR63433.1 - 0.011 16.1 1.5 0.014 15.6 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIVA PF05103.8 EMR63433.1 - 0.014 15.4 5.8 0.034 14.1 4.0 1.6 1 1 0 1 1 1 0 DivIVA protein Laminin_II PF06009.7 EMR63433.1 - 0.015 15.0 2.4 0.086 12.5 0.4 2.0 1 1 1 2 2 2 0 Laminin Domain II HlyD PF00529.15 EMR63433.1 - 0.017 14.4 0.8 0.02 14.2 0.6 1.0 1 0 0 1 1 1 0 HlyD family secretion protein V_ATPase_I PF01496.14 EMR63433.1 - 0.02 12.7 1.4 0.023 12.6 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 EMR63433.1 - 0.027 13.6 3.0 0.039 13.1 2.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding V-SNARE PF05008.10 EMR63433.1 - 0.028 14.5 3.9 2.6 8.2 1.2 2.4 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DivIC PF04977.10 EMR63433.1 - 0.031 13.7 1.6 0.031 13.7 1.1 2.1 2 0 0 2 2 2 0 Septum formation initiator Leu_zip PF15294.1 EMR63433.1 - 0.032 13.3 5.0 1.1 8.3 0.1 2.0 1 1 1 2 2 2 0 Leucine zipper DUF2203 PF09969.4 EMR63433.1 - 0.035 14.3 0.3 0.042 14.0 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) APG6 PF04111.7 EMR63433.1 - 0.041 12.9 6.1 0.052 12.5 4.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4200 PF13863.1 EMR63433.1 - 0.045 13.6 5.5 1.1 9.2 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3496 PF12001.3 EMR63433.1 - 0.046 13.9 0.6 0.06 13.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) Sipho_Gp157 PF05565.6 EMR63433.1 - 0.066 12.7 1.2 0.089 12.3 0.8 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 DUF3373 PF11853.3 EMR63433.1 - 0.077 11.5 0.5 0.087 11.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) TMPIT PF07851.8 EMR63433.1 - 0.077 12.0 0.9 0.089 11.8 0.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Spc24 PF08286.6 EMR63433.1 - 0.08 12.6 6.7 0.23 11.1 4.6 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 CHDCT2 PF08074.6 EMR63433.1 - 0.085 12.5 1.2 1.5 8.5 0.1 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain RasGAP_C PF03836.10 EMR63433.1 - 0.087 12.5 0.2 0.1 12.2 0.2 1.2 1 0 0 1 1 1 0 RasGAP C-terminus DUF4140 PF13600.1 EMR63433.1 - 0.13 12.7 8.7 0.13 12.7 2.1 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CENP-F_leu_zip PF10473.4 EMR63433.1 - 0.16 11.8 7.3 0.32 10.8 5.0 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.1 EMR63433.1 - 0.17 10.8 1.9 0.19 10.6 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SseC PF04888.7 EMR63433.1 - 0.17 11.2 1.3 0.23 10.7 0.9 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family PEARLI-4 PF05278.7 EMR63433.1 - 0.18 11.1 2.3 0.23 10.8 1.6 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4201 PF13870.1 EMR63433.1 - 0.18 11.2 6.5 0.12 11.7 1.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TBPIP PF07106.8 EMR63433.1 - 0.21 11.1 2.9 0.39 10.2 2.0 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PspA_IM30 PF04012.7 EMR63433.1 - 0.23 10.7 10.1 0.7 9.2 7.0 1.7 1 1 0 1 1 1 0 PspA/IM30 family Spc42p PF11544.3 EMR63433.1 - 0.25 11.3 1.8 0.35 10.8 1.2 1.4 1 0 0 1 1 1 0 Spindle pole body component Spc42p Prefoldin_2 PF01920.15 EMR63433.1 - 0.25 11.0 7.6 0.33 10.7 2.0 2.2 1 1 0 2 2 2 0 Prefoldin subunit DUF3166 PF11365.3 EMR63433.1 - 0.27 11.7 4.1 1 9.8 2.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) Sec2p PF06428.6 EMR63433.1 - 0.27 11.1 4.5 3.5 7.5 0.4 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p bZIP_1 PF00170.16 EMR63433.1 - 0.35 10.8 5.5 0.71 9.8 0.8 2.4 1 1 1 2 2 2 0 bZIP transcription factor Tropomyosin PF00261.15 EMR63433.1 - 0.47 9.4 14.2 0.12 11.4 6.8 1.8 1 1 0 1 1 1 0 Tropomyosin DUF4337 PF14235.1 EMR63433.1 - 0.49 10.2 8.5 1.3 8.8 5.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) ADIP PF11559.3 EMR63433.1 - 0.5 10.2 6.6 1.1 9.1 4.6 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 EMR63433.1 - 0.54 10.2 5.9 0.67 9.9 4.1 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EMR63433.1 - 0.56 9.7 8.9 0.92 9.0 6.1 1.3 1 1 0 1 1 1 0 IncA protein Pox_A_type_inc PF04508.7 EMR63433.1 - 0.8 9.6 6.0 13 5.9 0.4 3.2 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat TMF_DNA_bd PF12329.3 EMR63433.1 - 1.5 8.6 11.1 4.8 7.0 7.8 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.10 EMR63433.1 - 1.6 8.6 7.3 0.62 9.9 0.9 2.5 2 1 0 2 2 2 0 Basic region leucine zipper Mnd1 PF03962.10 EMR63433.1 - 2.1 7.9 6.9 3.9 7.0 4.8 1.4 1 1 0 1 1 1 0 Mnd1 family Bap31 PF05529.7 EMR63433.1 - 3.1 7.2 5.6 1.3 8.4 1.6 1.7 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Cwf_Cwc_15 PF04889.7 EMR63433.1 - 3.2 7.3 9.7 4.2 7.0 6.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GrpE PF01025.14 EMR63433.1 - 3.2 7.2 8.3 6 6.3 5.6 1.4 1 1 0 1 1 1 0 GrpE DUF4164 PF13747.1 EMR63433.1 - 7.5 6.7 12.3 13 5.9 2.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Vps35 PF03635.12 EMR63434.1 - 0 1024.4 0.0 0 1024.2 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Peptidase_M9_N PF08453.5 EMR63434.1 - 0.018 14.3 0.5 0.23 10.7 0.1 2.3 2 0 0 2 2 2 0 Peptidase family M9 N-terminal Meth_synt_2 PF01717.13 EMR63435.1 - 4.1e-18 65.4 0.0 5.3e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EMR63435.1 - 1.1e-07 31.4 0.0 0.015 14.5 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SNARE PF05739.14 EMR63436.1 - 4.6e-13 48.6 3.4 9.4e-13 47.6 2.3 1.6 1 0 0 1 1 1 1 SNARE domain LysM PF01476.15 EMR63437.1 - 3.1e-35 119.7 0.3 9.4e-07 28.6 0.0 5.9 6 0 0 6 6 6 4 LysM domain HTH_23 PF13384.1 EMR63437.1 - 1.1e-08 34.4 0.0 0.072 12.7 0.0 3.5 3 0 0 3 3 3 3 Homeodomain-like domain HTH_28 PF13518.1 EMR63437.1 - 2.3e-07 30.7 0.2 0.2 11.7 0.0 3.8 4 0 0 4 4 4 2 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EMR63437.1 - 1.1e-06 28.4 2.3 0.076 12.9 0.0 4.1 5 0 0 5 5 5 2 Transposase NLPC_P60 PF00877.14 EMR63437.1 - 0.00028 20.6 1.0 15 5.4 0.0 4.7 5 0 0 5 5 5 0 NlpC/P60 family CarbpepA_inh PF02977.10 EMR63437.1 - 0.0062 16.0 16.0 2.8 7.5 1.5 5.2 5 0 0 5 5 5 2 Carboxypeptidase A inhibitor HTH_7 PF02796.10 EMR63437.1 - 0.026 14.3 0.0 7 6.6 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase CENP-B_N PF04218.8 EMR63437.1 - 0.065 12.6 0.0 8.9 5.8 0.0 2.4 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain DUF3982 PF13138.1 EMR63437.1 - 0.16 11.8 4.1 2.6 7.9 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3982) UPF0203 PF05254.7 EMR63437.1 - 0.62 9.9 3.2 43 4.0 0.0 3.6 4 0 0 4 4 3 0 Uncharacterised protein family (UPF0203) zf-TFIIB PF13453.1 EMR63437.1 - 3.9 6.7 7.3 22 4.3 0.0 3.8 4 0 0 4 4 4 0 Transcription factor zinc-finger Glyco_hydro_18 PF00704.23 EMR63439.1 - 6.4e-46 157.3 0.8 9.5e-46 156.8 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EMR63439.1 - 8.6e-08 31.9 0.0 0.0015 18.3 0.0 2.6 2 0 0 2 2 2 2 LysM domain DUF3142 PF11340.3 EMR63439.1 - 0.019 14.6 0.0 0.048 13.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3142) DUF3165 PF11364.3 EMR63439.1 - 0.033 14.3 2.1 0.056 13.5 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) Phage_holin_1 PF04531.8 EMR63439.1 - 0.22 11.5 0.3 0.52 10.3 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage holin Mit_ribos_Mrp51 PF11709.3 EMR63440.1 - 0.0085 15.3 0.1 0.011 14.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Cep57_CLD_2 PF14197.1 EMR63440.1 - 0.067 13.1 4.2 0.12 12.3 2.9 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF1625 PF07787.7 EMR63440.1 - 0.73 9.0 5.6 1.3 8.2 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) Tetraspannin PF00335.15 EMR63440.1 - 4.7 6.4 7.4 8.2 5.6 5.1 1.3 1 0 0 1 1 1 0 Tetraspanin family Abhydrolase_5 PF12695.2 EMR63441.1 - 4.2e-23 81.7 0.0 6e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR63441.1 - 2.7e-15 56.8 0.0 1.2e-08 35.1 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR63441.1 - 4.7e-06 26.3 0.0 0.0089 15.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 EMR63441.1 - 2.6e-05 22.8 0.1 0.58 8.6 0.0 3.2 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 EMR63441.1 - 5.4e-05 22.8 0.0 8.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.7 EMR63441.1 - 0.00034 19.4 0.0 0.00048 18.9 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.13 EMR63441.1 - 0.00085 18.6 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EMR63441.1 - 0.0015 18.0 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EMR63441.1 - 0.0017 17.6 0.0 0.6 9.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.8 EMR63441.1 - 0.0067 15.8 0.0 0.08 12.3 0.0 2.1 1 1 1 2 2 2 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 EMR63441.1 - 0.052 13.2 0.0 2.1 8.0 0.0 2.2 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Amidoligase_2 PF12224.3 EMR63442.1 - 1.6e-18 67.2 0.0 6.2e-15 55.4 0.0 2.3 2 1 0 2 2 2 2 Putative amidoligase enzyme Pex2_Pex12 PF04757.9 EMR63443.1 - 4.5e-44 150.5 4.1 6.2e-44 150.1 2.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EMR63443.1 - 4.5e-12 45.5 7.9 9e-12 44.6 5.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMR63443.1 - 5.6e-12 45.4 7.7 9.9e-12 44.6 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMR63443.1 - 1.6e-10 40.4 4.7 2.6e-10 39.8 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMR63443.1 - 3.1e-10 39.5 6.3 5.9e-10 38.6 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR63443.1 - 1.9e-08 33.9 4.7 3.2e-08 33.1 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMR63443.1 - 6.3e-06 25.9 8.2 1.1e-05 25.1 5.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMR63443.1 - 0.00045 19.8 4.6 0.00099 18.7 3.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EMR63443.1 - 0.00068 19.6 6.6 0.0026 17.8 4.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EMR63443.1 - 0.0024 17.6 2.2 0.005 16.6 1.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EMR63443.1 - 0.24 11.0 8.5 0.45 10.1 5.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EMR63443.1 - 0.24 10.9 1.3 0.48 9.9 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ctr PF04145.10 EMR63443.1 - 0.27 11.2 1.3 0.97 9.4 0.9 2.1 1 1 0 1 1 1 0 Ctr copper transporter family EXS PF03124.9 EMR63444.1 - 5.9e-96 321.4 0.2 6.8e-96 321.2 0.1 1.0 1 0 0 1 1 1 1 EXS family MR_MLE_C PF13378.1 EMR63445.1 - 9.6e-33 112.4 0.1 1.8e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EMR63445.1 - 2.5e-08 34.3 0.0 5.8e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain F-box-like PF12937.2 EMR63446.1 - 0.0041 16.8 2.1 0.005 16.5 0.2 2.2 2 0 0 2 2 2 1 F-box-like Peptidase_M43 PF05572.8 EMR63447.1 - 1.7e-19 69.9 1.1 2.8e-19 69.2 0.8 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EMR63447.1 - 2.8e-06 27.4 0.2 4.1e-06 26.9 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EMR63447.1 - 0.00015 21.4 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.1 EMR63447.1 - 0.00045 20.1 3.7 0.00063 19.7 2.4 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMR63447.1 - 0.0005 20.5 0.6 0.0011 19.4 0.4 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMR63447.1 - 0.001 18.6 2.4 0.0015 18.1 1.7 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Cyt-b5 PF00173.23 EMR63448.1 - 8e-13 48.0 0.0 1.1e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PRA1 PF03208.14 EMR63448.1 - 0.066 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 PRA1 family protein Terpene_synth_C PF03936.11 EMR63449.1 - 1.8e-08 33.9 0.0 3.1e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Sec39 PF08314.6 EMR63449.1 - 0.13 10.2 0.0 0.17 9.7 0.0 1.1 1 0 0 1 1 1 0 Secretory pathway protein Sec39 Abhydrolase_3 PF07859.8 EMR63450.1 - 3.4e-55 186.8 0.0 4.4e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMR63450.1 - 2e-06 27.1 0.0 3.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMR63450.1 - 1e-05 25.5 1.6 1.7e-05 24.8 0.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR63450.1 - 5.4e-05 22.9 0.0 8.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EMR63450.1 - 0.00016 20.5 0.1 0.00039 19.2 0.1 1.6 1 1 1 2 2 2 1 Carboxylesterase family DLH PF01738.13 EMR63450.1 - 0.0037 16.5 0.0 0.0093 15.2 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family Glyco_transf_15 PF01793.11 EMR63453.1 - 1.3e-111 372.7 0.1 1.7e-111 372.3 0.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase zf-LYAR PF08790.6 EMR63454.1 - 5.6e-08 32.3 0.5 1.1e-07 31.4 0.4 1.5 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger MFS_1 PF07690.11 EMR63455.1 - 6.7e-24 84.2 28.4 1.1e-17 63.7 8.9 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR63455.1 - 2.7e-08 32.8 0.6 2.7e-08 32.8 0.4 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter ATG22 PF11700.3 EMR63455.1 - 0.0055 15.2 0.1 0.0055 15.2 0.0 3.4 2 2 1 3 3 3 2 Vacuole effluxer Atg22 like 7tm_1 PF00001.16 EMR63455.1 - 0.033 13.3 0.6 0.19 10.8 0.1 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF2615 PF11027.3 EMR63455.1 - 0.059 13.2 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) 7TM_GPCR_Srv PF10323.4 EMR63455.1 - 0.1 11.7 0.8 0.19 10.8 0.1 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv TMEM192 PF14802.1 EMR63455.1 - 0.2 10.5 0.0 0.4 9.4 0.0 1.4 1 0 0 1 1 1 0 TMEM192 family Ferrochelatase PF00762.14 EMR63456.1 - 1.6e-69 234.3 0.0 6.7e-47 159.9 0.0 2.0 1 1 1 2 2 2 2 Ferrochelatase Ku PF02735.11 EMR63457.1 - 2.7e-35 121.6 0.0 6.8e-35 120.2 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EMR63457.1 - 1.8e-33 115.8 0.2 3.2e-33 115.0 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EMR63457.1 - 1.1e-14 54.7 1.0 3.7e-14 53.0 0.7 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EMR63457.1 - 4.5e-11 41.9 1.4 4.5e-11 41.9 1.0 2.3 2 0 0 2 2 2 1 SAP domain LETM1 PF07766.8 EMR63457.1 - 0.095 11.7 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 LETM1-like protein Het-C PF07217.6 EMR63459.1 - 1.6e-274 911.7 0.4 2.5e-273 907.8 0.3 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C RabGAP-TBC PF00566.13 EMR63460.1 - 2.4e-51 174.2 0.0 3.3e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_tranf_2_3 PF13641.1 EMR63461.1 - 2.7e-14 53.5 0.0 3.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMR63461.1 - 0.00058 19.5 0.0 0.00086 19.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMR63461.1 - 0.002 17.4 0.1 0.016 14.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 p450 PF00067.17 EMR63462.1 - 5.2e-43 147.2 0.0 7e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_5 PF06172.6 EMR63463.1 - 1.1e-41 142.0 0.0 1.2e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) GYF PF02213.11 EMR63464.1 - 4.4e-18 64.5 0.1 9.4e-18 63.5 0.1 1.6 1 0 0 1 1 1 1 GYF domain Hid1 PF12722.2 EMR63464.1 - 3.4 5.2 2.6 5.8 4.4 1.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CN_hydrolase PF00795.17 EMR63465.1 - 9.8e-17 60.8 0.0 1.4e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase V-SNARE_C PF12352.3 EMR63468.1 - 1.3e-14 54.0 2.9 2.8e-14 52.9 0.1 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EMR63468.1 - 1.2e-05 24.9 0.0 3.6e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Sec20 Sigma70_r4 PF04545.11 EMR63468.1 - 0.032 13.5 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 MscS_porin PF12795.2 EMR63468.1 - 0.87 8.8 6.9 0.074 12.3 1.1 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain TPR_16 PF13432.1 EMR63469.1 - 4.9e-10 39.7 1.1 4.9e-10 39.7 0.8 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMR63469.1 - 1.1e-09 37.8 0.7 4.8e-06 26.1 0.2 3.8 3 1 2 5 5 5 3 TPR repeat TPR_1 PF00515.23 EMR63469.1 - 1.1e-06 27.9 0.4 0.0045 16.5 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMR63469.1 - 1.4e-06 27.8 7.0 0.002 17.9 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMR63469.1 - 8.6e-06 25.9 3.0 0.0021 18.5 0.1 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMR63469.1 - 1.1e-05 24.8 0.1 0.058 13.2 0.0 3.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMR63469.1 - 6.1e-05 22.8 1.3 0.0059 16.5 0.4 3.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMR63469.1 - 0.00023 20.7 0.0 0.01 15.5 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMR63469.1 - 0.0025 17.6 0.2 0.011 15.6 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat Peptidase_C12 PF01088.16 EMR63470.1 - 1.2e-49 168.3 1.2 1.4e-32 112.6 0.2 3.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 Mito_carr PF00153.22 EMR63471.1 - 7.3e-62 205.1 5.7 6.3e-23 80.2 0.1 4.0 2 2 2 4 4 4 4 Mitochondrial carrier protein CDP-OH_P_transf PF01066.16 EMR63474.1 - 6.8e-14 52.0 3.5 1.3e-13 51.1 2.4 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase HET PF06985.6 EMR63475.1 - 2e-30 105.8 0.2 3.6e-30 104.9 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APG9 PF04109.11 EMR63476.1 - 1.3e-71 241.5 1.5 1.6e-71 241.2 1.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 BAF1_ABF1 PF04684.8 EMR63476.1 - 3.2 6.5 6.3 4.6 5.9 4.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Fungal_trans_2 PF11951.3 EMR63477.1 - 5.9e-11 41.5 0.2 1.9e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR63477.1 - 2.5e-06 27.2 12.3 2.5e-06 27.2 8.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FA_desaturase PF00487.19 EMR63478.1 - 7.4e-35 120.6 27.3 1.1e-34 120.0 18.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EMR63478.1 - 1.1e-10 41.0 0.0 2.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Metallopep PF12044.3 EMR63480.1 - 2.6e-144 480.7 0.0 3.1e-144 480.5 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 EMR63480.1 - 0.0064 16.3 0.0 0.018 14.9 0.0 1.7 1 1 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.1 EMR63480.1 - 0.043 13.7 0.4 0.066 13.1 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EMR63480.1 - 0.057 13.4 0.5 0.1 12.6 0.4 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Paf1 PF03985.8 EMR63482.1 - 3.6 6.2 10.7 0.13 11.0 3.1 1.6 2 0 0 2 2 2 0 Paf1 Syndecan PF01034.15 EMR63483.1 - 0.038 13.6 1.1 0.071 12.7 0.7 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 EMR63483.1 - 4 6.8 8.1 1.3 8.3 0.5 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DnaJ PF00226.26 EMR63484.1 - 1.8e-23 82.0 3.9 1.9e-23 81.9 1.0 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_8 PF13181.1 EMR63484.1 - 1.9e-16 58.4 2.8 0.0034 17.0 0.0 7.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMR63484.1 - 2.9e-16 58.8 14.7 1.3e-09 37.5 0.0 5.8 2 2 6 8 8 8 5 TPR repeat TPR_16 PF13432.1 EMR63484.1 - 8.9e-13 48.5 9.7 0.00078 20.0 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMR63484.1 - 1.5e-12 46.5 5.4 0.0035 16.9 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMR63484.1 - 7.3e-12 44.2 12.1 0.0093 15.8 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMR63484.1 - 1.8e-08 34.2 8.3 0.043 14.4 0.0 6.7 4 2 4 8 8 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMR63484.1 - 2.7e-08 33.3 2.5 0.0052 16.8 0.1 5.9 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMR63484.1 - 2.7e-07 30.3 1.7 9.6e-05 22.1 0.0 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMR63484.1 - 6.3e-07 28.7 8.5 0.0017 17.9 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR63484.1 - 4.2e-06 26.9 11.2 0.094 13.0 0.1 5.2 3 1 4 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 EMR63484.1 - 7.7e-06 26.0 12.2 0.16 12.5 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMR63484.1 - 2.3e-05 24.2 14.7 0.38 10.7 0.0 5.8 2 2 5 7 7 7 2 Tetratricopeptide repeat HemY_N PF07219.8 EMR63484.1 - 0.03 13.8 0.4 0.03 13.8 0.3 2.4 3 0 0 3 3 3 0 HemY protein N-terminus DUF3220 PF11516.3 EMR63484.1 - 0.053 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Apc3 PF12895.2 EMR63484.1 - 0.16 12.1 12.5 0.17 12.0 0.0 3.9 4 1 1 5 5 3 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 EMR63484.1 - 0.21 11.9 9.1 0.99 9.7 0.0 4.4 3 1 2 5 5 5 0 Bacterial transcriptional activator domain DUF3856 PF12968.2 EMR63484.1 - 0.67 9.7 5.6 1.6 8.5 0.2 3.6 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) Glyco_hydro_71 PF03659.9 EMR63485.1 - 1.2e-65 221.5 0.0 1.8e-65 220.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 COG6 PF06419.6 EMR63486.1 - 4.2e-228 758.5 4.5 4.8e-228 758.3 3.1 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 RmuC PF02646.11 EMR63486.1 - 0.021 13.6 1.6 0.038 12.8 0.4 1.9 2 0 0 2 2 2 0 RmuC family DASH_Dad3 PF08656.5 EMR63486.1 - 0.035 13.7 6.3 0.24 11.1 0.1 4.2 4 2 0 4 4 4 0 DASH complex subunit Dad3 DUF948 PF06103.6 EMR63486.1 - 0.12 12.2 1.1 0.44 10.4 0.3 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Whi5 PF08528.6 EMR63487.1 - 8.5e-11 41.1 0.2 1.6e-10 40.3 0.2 1.5 1 0 0 1 1 1 1 Whi5 like eIF_4EBP PF05456.6 EMR63487.1 - 0.13 11.9 3.7 0.22 11.2 1.4 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CBS PF00571.23 EMR63488.1 - 0.0023 17.6 0.1 0.05 13.4 0.0 2.7 2 1 0 2 2 2 1 CBS domain AA_permease_2 PF13520.1 EMR63489.1 - 2.9e-71 240.2 41.2 3.5e-71 239.9 28.6 1.1 1 0 0 1 1 1 1 Amino acid permease SurE PF01975.12 EMR63490.1 - 2.8e-32 111.6 0.0 3.9e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_trans_4_4 PF13579.1 EMR63490.1 - 0.02 15.0 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain PGM_PMM_I PF02878.11 EMR63491.1 - 4.1e-34 117.0 0.0 6e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EMR63491.1 - 8.9e-25 86.9 0.0 1.7e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EMR63491.1 - 6.7e-15 55.2 0.0 1.4e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EMR63491.1 - 1.6e-07 31.2 0.0 3.7e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Glyco_hydro_cc PF11790.3 EMR63492.1 - 5.8e-28 97.9 0.1 7e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core MFS_1 PF07690.11 EMR63493.1 - 2.3e-20 72.6 41.6 6.8e-20 71.0 28.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR63493.1 - 4.9e-08 31.9 16.8 4.9e-08 31.9 11.6 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Polysacc_lyase PF14099.1 EMR63494.1 - 3.6e-42 144.5 9.3 4.4e-42 144.2 6.4 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Laminin_G_3 PF13385.1 EMR63494.1 - 0.036 14.3 5.6 0.043 14.0 3.6 1.5 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Methyltransf_18 PF12847.2 EMR63496.1 - 1.9e-10 41.3 0.0 3.9e-10 40.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR63496.1 - 3.9e-09 36.8 0.0 9.9e-08 32.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR63496.1 - 8.6e-09 35.3 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR63496.1 - 2.3e-08 34.4 0.0 9.7e-07 29.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR63496.1 - 6.9e-07 29.5 0.0 3.4e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR63496.1 - 2.1e-05 24.1 0.0 0.00023 20.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EMR63496.1 - 0.00018 20.6 0.0 0.012 14.6 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EMR63496.1 - 0.00074 19.5 0.1 0.0014 18.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR63496.1 - 0.0061 15.9 0.0 0.96 8.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EMR63496.1 - 0.058 12.5 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.9 EMR63496.1 - 0.082 12.0 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_7 PF03492.10 EMR63496.1 - 0.14 10.9 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Ank_5 PF13857.1 EMR63498.1 - 9.3e-13 47.9 0.1 5.9e-11 42.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR63498.1 - 7.2e-07 29.5 0.0 0.0012 19.3 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMR63498.1 - 8.6e-07 29.2 0.3 8.1e-05 22.8 0.1 2.6 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) VPS9 PF02204.13 EMR63498.1 - 6.3e-05 22.9 0.1 0.00013 21.9 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank PF00023.25 EMR63498.1 - 9.8e-05 21.9 0.2 0.0055 16.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EMR63498.1 - 0.0025 17.8 0.3 0.56 10.6 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat AMIN PF11741.3 EMR63498.1 - 0.074 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 AMIN domain RNase_T PF00929.19 EMR63499.1 - 9.6e-25 87.7 0.1 1.1e-24 87.5 0.1 1.0 1 0 0 1 1 1 1 Exonuclease LIX1 PF14954.1 EMR63499.1 - 0.095 11.6 0.5 1.1 8.2 0.1 2.0 2 0 0 2 2 2 0 Limb expression 1 Cupin_2 PF07883.6 EMR63500.1 - 3.7e-07 29.5 0.0 5.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EMR63500.1 - 0.00033 19.9 0.0 0.00047 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EMR63500.1 - 0.072 12.6 0.0 0.08 12.5 0.0 1.1 1 0 0 1 1 1 0 Cupin adh_short PF00106.20 EMR63503.1 - 4.7e-15 55.9 0.0 5.5e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR63503.1 - 3.1e-06 26.9 0.0 5.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR63503.1 - 6.1e-06 25.8 0.0 8.1e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMR63503.1 - 0.06 12.2 0.0 0.12 11.2 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EMR63503.1 - 0.12 11.3 0.0 0.24 10.3 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase Abhydrolase_3 PF07859.8 EMR63504.1 - 1.9e-07 30.8 1.9 3.1e-07 30.1 1.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR63504.1 - 8.9e-05 22.2 0.5 0.00017 21.3 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EMR63504.1 - 0.00025 19.9 0.1 0.00055 18.7 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EMR63504.1 - 0.00039 20.3 1.9 0.00039 20.3 1.3 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DEAD PF00270.24 EMR63505.1 - 7.2e-30 103.6 0.2 3.6e-19 68.8 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase DUF4217 PF13959.1 EMR63505.1 - 4.3e-22 77.4 0.3 9.1e-22 76.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EMR63505.1 - 3.1e-21 75.0 0.0 5.9e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2457 PF10446.4 EMR63505.1 - 2.6e-05 23.1 16.5 3.7e-05 22.6 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Daxx PF03344.10 EMR63505.1 - 0.034 12.6 17.0 0.047 12.1 11.8 1.1 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 EMR63505.1 - 0.57 9.1 19.2 0.82 8.6 13.3 1.2 1 0 0 1 1 1 0 BUD22 ResIII PF04851.10 EMR63505.1 - 1.5 8.6 5.4 0.88 9.3 0.1 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Red1 PF07964.6 EMR63505.1 - 1.5 6.8 9.9 2.1 6.4 6.9 1.1 1 0 0 1 1 1 0 Rec10 / Red1 DIOX_N PF14226.1 EMR63506.1 - 1.1e-08 35.6 0.0 2.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMR63506.1 - 3.1e-07 30.5 0.0 5.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAA_hydrolase PF01557.13 EMR63508.1 - 1.3e-43 149.0 0.0 1.5e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family CaATP_NAI PF12515.3 EMR63509.1 - 0.041 13.3 0.0 0.12 11.8 0.0 1.8 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain 2OG-FeII_Oxy_3 PF13640.1 EMR63510.1 - 1.7e-05 25.2 0.1 3.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMR63510.1 - 3.1e-05 24.1 0.0 6.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cellulase PF00150.13 EMR63512.1 - 5.2e-12 45.5 1.7 1.2e-11 44.3 1.1 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short PF00106.20 EMR63513.1 - 1.6e-16 60.6 2.1 2.4e-16 60.1 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR63513.1 - 1.1e-09 38.1 0.6 1.7e-09 37.6 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR63513.1 - 0.039 13.3 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F-box PF00646.28 EMR63514.1 - 0.0013 18.2 0.1 0.0073 15.9 0.0 2.2 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.2 EMR63514.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 F-box-like Alpha_L_fucos PF01120.12 EMR63515.1 - 1.7e-29 102.8 0.1 1.4e-28 99.8 0.0 2.3 1 1 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.20 EMR63515.1 - 1.7e-12 47.2 1.1 2.8e-12 46.5 0.0 1.9 2 0 0 2 2 2 1 F5/8 type C domain GHL6 PF14871.1 EMR63515.1 - 0.064 13.2 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Methyltransf_25 PF13649.1 EMR63518.1 - 3.4e-10 40.2 0.3 8.8e-10 38.8 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR63518.1 - 1.5e-05 25.3 0.1 3.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR63518.1 - 5.3e-05 23.6 0.0 0.00017 22.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR63518.1 - 0.00063 20.3 0.1 0.0015 19.0 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR63518.1 - 0.0013 18.3 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR63518.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 EMR63520.1 - 3e-55 182.2 13.5 2.4e-09 36.7 0.1 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box PF00646.28 EMR63520.1 - 2e-11 43.2 2.6 3.9e-11 42.2 0.6 2.4 2 1 1 3 3 3 1 F-box domain F-box-like PF12937.2 EMR63520.1 - 5.8e-11 41.9 0.4 1.1e-10 41.0 0.3 1.5 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.1 EMR63520.1 - 0.00049 19.6 1.0 1.4 8.3 0.0 3.1 2 1 0 3 3 3 2 PQQ-like domain PRANC PF09372.5 EMR63520.1 - 0.053 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 PRANC domain UMPH-1 PF05822.7 EMR63520.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) GST_N_3 PF13417.1 EMR63521.1 - 2.3e-14 53.3 0.0 1.4e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMR63521.1 - 1.6e-11 44.0 0.0 3.4e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMR63521.1 - 1.7e-11 44.0 0.0 1e-10 41.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR63521.1 - 2.7e-10 40.0 0.0 4.6e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMR63521.1 - 1.8e-09 37.3 0.1 2.9e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR63521.1 - 4e-08 33.6 0.1 6.7e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PMP1_2 PF08114.6 EMR63522.1 - 0.0041 16.5 0.7 0.0073 15.7 0.5 1.4 1 0 0 1 1 1 1 ATPase proteolipid family MliC PF09864.4 EMR63522.1 - 0.0072 16.0 0.3 0.019 14.7 0.2 1.9 1 0 0 1 1 1 1 Membrane-bound lysozyme-inhibitor of c-type lysozyme Protocadherin PF08374.6 EMR63522.1 - 0.11 12.1 0.1 0.63 9.6 0.0 1.9 2 0 0 2 2 2 0 Protocadherin Arylsulfotran_2 PF14269.1 EMR63523.1 - 3.1e-55 187.4 3.3 3.8e-55 187.1 2.3 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EMR63523.1 - 5.3e-18 64.7 2.0 1.4e-17 63.3 1.4 1.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DAO PF01266.19 EMR63524.1 - 6.6e-28 97.6 8.2 3.6e-27 95.1 5.7 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR63524.1 - 0.0017 18.4 0.0 0.61 10.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR63524.1 - 0.01 15.6 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR63524.1 - 0.064 13.0 0.4 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding 4HBT PF03061.17 EMR63525.1 - 0.0013 18.8 0.9 0.046 13.8 0.1 2.3 2 0 0 2 2 2 2 Thioesterase superfamily TPR_11 PF13414.1 EMR63528.1 - 0.1 12.2 0.8 1.3 8.6 0.0 2.8 3 0 0 3 3 3 0 TPR repeat Pirin PF02678.11 EMR63530.1 - 8.8e-32 109.1 0.0 1.5e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EMR63530.1 - 3.2e-25 88.2 0.0 1.1e-23 83.3 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EMR63530.1 - 1.5e-06 27.5 0.4 2.6e-05 23.6 0.2 2.4 2 0 0 2 2 2 1 Cupin domain Het-C PF07217.6 EMR63531.1 - 0.026 12.7 0.4 0.33 9.0 0.6 1.9 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C Cellulose_synt PF03552.9 EMR63531.1 - 0.082 11.1 0.1 0.11 10.7 0.1 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF2956 PF11169.3 EMR63531.1 - 0.092 12.7 2.2 0.2 11.6 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Ctr PF04145.10 EMR63531.1 - 0.14 12.1 4.1 4.3 7.3 1.6 2.4 2 0 0 2 2 2 0 Ctr copper transporter family Secretin_N_2 PF07655.8 EMR63531.1 - 2.1 8.7 20.1 1.4 9.3 0.1 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Pex14_N PF04695.8 EMR63531.1 - 2.7 8.0 10.1 0.82 9.7 2.8 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAD_binding_3 PF01494.14 EMR63532.1 - 4.8e-24 85.0 0.0 1.3e-23 83.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR63532.1 - 5.5e-10 38.6 0.0 9.5e-05 21.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR63532.1 - 6.1e-07 28.2 0.0 9.3e-05 21.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EMR63532.1 - 7.2e-07 29.2 0.3 8.2e-06 25.8 0.2 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR63532.1 - 8.6e-07 28.1 0.0 1.5e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMR63532.1 - 1.9e-06 27.8 0.0 5.5e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMR63532.1 - 1.2e-05 24.5 0.1 3.6e-05 23.0 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EMR63532.1 - 0.0003 19.7 0.0 0.011 14.6 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EMR63532.1 - 0.00052 20.1 0.0 0.0019 18.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR63532.1 - 0.0032 17.2 0.1 0.033 13.9 0.1 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EMR63532.1 - 0.0049 17.2 0.0 0.064 13.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR63532.1 - 0.0062 15.4 0.0 0.25 10.2 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 EMR63532.1 - 0.035 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EMR63532.1 - 0.06 11.9 0.1 2.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_10 PF13460.1 EMR63532.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding ABC_tran PF00005.22 EMR63533.1 - 2.8e-45 153.9 0.1 5.5e-23 81.7 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMR63533.1 - 1.7e-17 64.3 0.0 0.00066 19.7 0.0 4.6 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EMR63533.1 - 5.1e-15 55.2 0.1 9.5e-05 21.7 0.0 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMR63533.1 - 2.8e-11 44.1 3.1 8.4e-06 26.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EMR63533.1 - 5.7e-10 38.5 0.0 0.0014 18.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EMR63533.1 - 5.7e-08 33.6 0.0 0.0052 17.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMR63533.1 - 2.8e-07 29.8 0.0 0.0016 17.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EMR63533.1 - 4e-07 29.7 0.1 0.13 11.6 0.0 3.7 4 0 0 4 4 4 2 AAA-like domain AAA_28 PF13521.1 EMR63533.1 - 4.9e-07 29.8 0.0 0.013 15.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMR63533.1 - 5.3e-07 29.8 0.0 0.0045 17.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EMR63533.1 - 5.6e-07 29.5 0.0 0.0063 16.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 EMR63533.1 - 1.5e-06 27.5 3.3 0.14 11.1 0.0 4.9 4 1 1 5 5 5 1 AAA ATPase domain Dynamin_N PF00350.18 EMR63533.1 - 2.1e-06 27.6 0.0 0.00037 20.3 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.1 EMR63533.1 - 2.5e-06 27.3 0.0 0.13 12.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EMR63533.1 - 9.7e-06 25.9 0.5 0.22 11.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 EMR63533.1 - 1.7e-05 25.2 0.0 0.068 13.6 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein MobB PF03205.9 EMR63533.1 - 1.8e-05 24.4 0.0 0.25 11.0 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 EMR63533.1 - 1.9e-05 24.4 0.0 0.05 13.5 0.0 3.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EMR63533.1 - 2.2e-05 24.6 0.0 0.41 10.8 0.0 4.0 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 EMR63533.1 - 2.8e-05 23.0 0.1 0.14 10.9 0.0 2.5 2 0 0 2 2 2 2 ArgK protein PduV-EutP PF10662.4 EMR63533.1 - 9.4e-05 21.9 0.0 0.11 11.9 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EMR63533.1 - 0.00012 22.2 0.0 1 9.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.1 EMR63533.1 - 0.00014 21.7 0.0 1 9.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 EMR63533.1 - 0.00015 21.4 0.1 0.059 13.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EMR63533.1 - 0.00024 21.1 0.1 0.93 9.4 0.0 3.5 4 0 0 4 4 3 1 AAA ATPase domain AAA_13 PF13166.1 EMR63533.1 - 0.00032 19.3 2.1 1.3 7.3 0.0 3.7 3 1 1 4 4 4 1 AAA domain Arch_ATPase PF01637.13 EMR63533.1 - 0.0009 19.0 0.0 1.2 8.7 0.0 2.8 2 0 0 2 2 2 1 Archaeal ATPase DUF87 PF01935.12 EMR63533.1 - 0.0012 18.7 0.8 0.75 9.5 0.0 3.3 3 0 0 3 3 2 1 Domain of unknown function DUF87 Septin PF00735.13 EMR63533.1 - 0.0018 17.3 1.0 1.8 7.4 0.0 3.4 3 0 0 3 3 3 1 Septin AAA_30 PF13604.1 EMR63533.1 - 0.0027 17.3 0.0 4.8 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EMR63533.1 - 0.0027 17.1 0.6 1.9 7.8 0.0 3.1 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EMR63533.1 - 0.0032 16.9 0.1 1.3 8.3 0.0 3.3 4 0 0 4 4 2 1 AAA domain MutS_V PF00488.16 EMR63533.1 - 0.0068 15.8 0.1 0.56 9.5 0.0 2.4 2 0 0 2 2 2 1 MutS domain V ATP-synt_ab PF00006.20 EMR63533.1 - 0.0069 15.9 0.0 0.68 9.3 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 EMR63533.1 - 0.018 14.6 0.1 7 6.1 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 EMR63533.1 - 0.024 13.7 0.0 4.9 6.2 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 EMR63533.1 - 0.03 13.8 0.1 3.2 7.1 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family HEAT_2 PF13646.1 EMR63533.1 - 0.04 14.1 0.0 0.59 10.4 0.0 2.7 1 1 1 2 2 2 0 HEAT repeats PRK PF00485.13 EMR63533.1 - 0.045 13.3 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.16 EMR63533.1 - 0.064 12.4 0.1 5.8 6.0 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EMR63533.1 - 0.065 12.1 0.0 11 4.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) T2SE PF00437.15 EMR63533.1 - 0.074 11.9 0.1 6.5 5.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 EMR63533.1 - 0.092 12.1 0.0 16 4.8 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.1 EMR63533.1 - 0.093 12.4 0.0 6 6.6 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain Ifi-6-16 PF06140.8 EMR63533.1 - 0.14 11.9 0.3 0.3 10.9 0.2 1.5 1 0 0 1 1 1 0 Interferon-induced 6-16 family ParcG PF10274.4 EMR63533.1 - 0.15 11.9 0.3 2.3 8.0 0.0 2.5 1 1 1 2 2 2 0 Parkin co-regulated protein BDHCT PF08072.6 EMR63533.1 - 1.8 8.7 3.5 3.1 7.9 0.1 2.5 2 0 0 2 2 2 0 BDHCT (NUC031) domain WD40 PF00400.27 EMR63535.1 - 1.2e-34 116.9 4.0 7.8e-09 35.0 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EMR63535.1 - 3.8e-27 93.9 0.3 1.6e-26 92.0 0.1 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Apc4_WD40 PF12894.2 EMR63535.1 - 0.0017 17.7 0.1 0.14 11.6 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4059 PF13268.1 EMR63535.1 - 0.16 12.1 0.2 0.46 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) CENP-I PF07778.6 EMR63536.1 - 7.4e-55 186.0 0.2 7.4e-42 143.2 0.0 2.1 1 1 1 2 2 2 2 Mis6 DUF410 PF04190.8 EMR63538.1 - 1.6e-49 168.8 0.0 1.9e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Aminotran_1_2 PF00155.16 EMR63539.1 - 3e-08 32.9 0.0 8.5e-08 31.5 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Cse1 PF08506.5 EMR63540.1 - 6e-153 508.7 3.3 8.9e-153 508.2 2.3 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 EMR63540.1 - 1.3e-119 399.3 0.0 1.1e-71 241.4 0.0 2.4 1 1 1 2 2 2 2 CAS/CSE protein, C-terminus IBN_N PF03810.14 EMR63540.1 - 1.2e-11 44.3 0.1 3.6e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EMR63540.1 - 0.0074 16.2 3.0 0.41 10.5 0.0 4.2 4 1 0 4 4 4 1 Exportin 1-like protein CAF1A PF12253.3 EMR63541.1 - 5.2e-20 71.3 4.8 5.2e-20 71.3 3.3 3.2 4 0 0 4 4 4 1 Chromatin assembly factor 1 subunit A Bud13 PF09736.4 EMR63541.1 - 0.26 11.5 15.6 0.7 10.1 10.8 1.8 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex GBP_C PF02841.9 EMR63541.1 - 2.1 7.4 23.6 3.7 6.6 16.4 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain CAF-1_p150 PF11600.3 EMR63541.1 - 3.2 7.0 53.0 2.1 7.6 32.9 2.8 2 1 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Vfa1 PF08432.5 EMR63541.1 - 7.8 6.4 29.3 21 5.0 17.2 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 FAM60A PF15396.1 EMR63541.1 - 8 6.1 13.4 15 5.2 9.3 1.5 1 0 0 1 1 1 0 Protein Family FAM60A FHIPEP PF00771.15 EMR63541.1 - 8.2 4.6 6.9 11 4.2 4.8 1.2 1 0 0 1 1 1 0 FHIPEP family LMBR1 PF04791.11 EMR63541.1 - 9.1 4.7 5.5 15 4.0 3.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Ribosomal_60s PF00428.14 EMR63542.1 - 0.04 14.3 3.3 0.072 13.4 2.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein RAI1 PF08652.6 EMR63543.1 - 1e-28 98.8 0.0 2.7e-28 97.5 0.0 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease MTHFR PF02219.12 EMR63544.1 - 2.5e-99 332.0 0.0 5e-99 331.0 0.0 1.4 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase TB2_DP1_HVA22 PF03134.14 EMR63545.1 - 5e-31 106.2 6.5 7.3e-31 105.7 4.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4407 PF14362.1 EMR63545.1 - 0.26 10.2 0.7 1.8 7.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Bestrophin PF01062.16 EMR63545.1 - 1 8.2 10.7 7.6 5.3 7.4 1.9 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel ABC_tran PF00005.22 EMR63546.1 - 6.3e-16 58.9 0.0 6.5e-15 55.6 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMR63546.1 - 2.4e-09 37.6 0.0 0.00038 20.5 0.1 2.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EMR63546.1 - 0.00033 20.1 0.1 0.0006 19.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 EMR63546.1 - 0.00077 16.9 0.2 0.00099 16.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_15 PF13175.1 EMR63546.1 - 0.00096 18.3 0.0 0.28 10.1 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain PduV-EutP PF10662.4 EMR63546.1 - 0.0041 16.6 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.14 EMR63546.1 - 0.0064 15.7 0.0 2.9 7.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMR63546.1 - 0.0069 16.3 0.4 0.015 15.2 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 EMR63546.1 - 0.01 15.8 0.3 0.019 14.9 0.2 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EMR63546.1 - 0.011 15.1 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 EMR63546.1 - 0.013 14.8 0.3 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EMR63546.1 - 0.017 15.4 0.0 0.024 14.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMR63546.1 - 0.017 15.9 0.2 0.029 15.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EMR63546.1 - 0.025 14.0 0.1 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.24 EMR63546.1 - 0.025 14.7 0.1 0.085 13.0 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR63546.1 - 0.043 13.9 0.2 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EMR63546.1 - 0.06 12.5 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EMR63546.1 - 0.093 12.6 0.0 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 EMR63546.1 - 0.1 11.8 0.0 0.24 10.6 0.0 1.6 2 0 0 2 2 1 0 ADP-ribosylation factor family NACHT PF05729.7 EMR63546.1 - 0.15 11.7 0.2 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 EMR63546.1 - 0.15 11.9 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EMR63546.1 - 0.16 11.8 0.1 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 Dynamin family AAA_13 PF13166.1 EMR63546.1 - 0.16 10.3 0.0 0.21 9.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EMR63546.1 - 0.17 11.2 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain cobW PF02492.14 EMR63546.1 - 0.2 11.1 0.3 0.36 10.2 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AA_kinase PF00696.23 EMR63548.1 - 1.4e-33 116.4 0.2 3.6e-33 115.1 0.0 1.8 2 1 0 2 2 2 1 Amino acid kinase family ACT PF01842.20 EMR63548.1 - 1.7e-15 56.1 1.5 6.8e-10 38.2 0.1 2.9 2 1 0 2 2 2 2 ACT domain ACT_7 PF13840.1 EMR63548.1 - 2.8e-13 49.1 5.3 6e-10 38.5 0.3 2.6 2 0 0 2 2 2 2 ACT domain DUF3384 PF11864.3 EMR63549.1 - 1.6e-99 333.4 0.0 3e-99 332.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EMR63549.1 - 7.3e-57 191.7 0.0 2.7e-56 189.9 0.0 1.9 2 0 0 2 2 2 1 Rap/ran-GAP Tuberin PF03542.11 EMR63549.1 - 7.5e-10 38.4 0.4 2.9e-08 33.1 0.1 2.3 2 0 0 2 2 2 1 Tuberin IucA_IucC PF04183.7 EMR63549.1 - 0.019 14.2 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 IucA / IucC family IF4E PF01652.13 EMR63550.1 - 3.1e-49 166.6 0.2 4.3e-49 166.2 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1917 PF08939.5 EMR63550.1 - 0.011 15.5 1.1 0.018 14.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) XRN_N PF03159.13 EMR63551.1 - 4.8e-103 343.6 0.0 7.6e-103 342.9 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Glyco_hydro_3 PF00933.16 EMR63552.1 - 7.7e-81 271.3 0.1 1.1e-80 270.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR63552.1 - 2.7e-54 184.0 0.0 2.6e-53 180.8 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR63552.1 - 3.2e-23 81.4 0.6 6.6e-23 80.4 0.4 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF2181 PF10223.4 EMR63553.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) zf-RanBP PF00641.13 EMR63554.1 - 2.1e-18 65.1 13.3 7.1e-11 41.0 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EMR63554.1 - 9.8e-09 34.7 0.0 2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EMR63554.1 - 8.1e-06 26.2 0.0 1.3e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 EMR63554.1 - 9.4e-06 25.5 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 EMR63554.1 - 4.8 7.0 11.3 0.85 9.4 0.9 2.4 2 0 0 2 2 2 0 Double zinc ribbon Kin17_mid PF10357.4 EMR63555.1 - 1.4e-29 102.3 6.6 8.8e-21 73.8 0.1 2.8 2 1 1 3 3 3 2 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EMR63555.1 - 7.6e-06 25.9 0.4 1.3e-05 25.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMR63555.1 - 5.4e-05 23.2 0.8 9.4e-05 22.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMR63555.1 - 0.0037 17.3 0.2 0.0068 16.5 0.2 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Menin PF05053.8 EMR63555.1 - 0.13 10.4 4.9 0.17 9.9 3.4 1.2 1 0 0 1 1 1 0 Menin Acetyltransf_1 PF00583.19 EMR63556.1 - 5.8e-08 32.6 0.1 3.4e-07 30.1 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EMR63556.1 - 6.2e-06 26.0 0.0 0.00015 21.5 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR63556.1 - 5.6e-05 23.2 0.1 0.00022 21.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR63556.1 - 0.0017 18.4 0.1 0.0035 17.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EMR63556.1 - 0.055 13.0 0.2 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR63556.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Glyco_hydro_88 PF07470.8 EMR63557.1 - 8.8e-13 47.9 0.6 8.2e-12 44.8 0.1 1.9 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 Ribosomal_L4 PF00573.17 EMR63558.1 - 3.2e-39 134.3 0.3 4.2e-39 133.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EMR63558.1 - 6.4e-27 93.2 0.5 6.4e-27 93.2 0.3 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Peptidase_M35 PF02102.10 EMR63559.1 - 3.9e-67 226.4 22.3 1.3e-66 224.6 15.4 1.6 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EMR63559.1 - 3.1e-09 37.4 1.3 4.8e-09 36.8 0.6 1.5 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase IceA2 PF05862.6 EMR63559.1 - 0.089 12.5 1.9 20 5.0 0.0 3.3 3 0 0 3 3 3 0 Helicobacter pylori IceA2 protein Big_4 PF07532.6 EMR63559.1 - 0.11 12.0 0.1 0.29 10.6 0.1 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) Cyclase PF04199.8 EMR63560.1 - 6e-08 32.5 0.0 8.1e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.19 EMR63561.1 - 3.2e-65 220.4 13.9 3.7e-65 220.2 9.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1996 PF09362.5 EMR63562.1 - 4.4e-65 219.6 0.0 6.8e-65 219.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EMR63562.1 - 2.5e-32 110.6 24.6 2.5e-16 59.3 6.8 2.6 2 0 0 2 2 2 2 WSC domain Peptidase_M1 PF01433.15 EMR63563.1 - 3e-10 39.7 0.1 0.0015 17.7 0.0 3.2 3 0 0 3 3 3 3 Peptidase family M1 HEAT PF02985.17 EMR63563.1 - 3.8 7.8 4.5 33 4.9 0.0 3.4 4 0 0 4 4 4 0 HEAT repeat ERO1 PF04137.10 EMR63564.1 - 8.4e-138 459.2 0.0 1.3e-137 458.6 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Prok-TraM PF09228.5 EMR63564.1 - 0.07 13.2 0.5 0.21 11.7 0.1 1.9 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM PBP1_TM PF14812.1 EMR63564.1 - 0.65 10.3 7.3 0.48 10.7 1.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fasciclin PF02469.17 EMR63565.1 - 0.0056 16.6 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain DUF3176 PF11374.3 EMR63567.1 - 1.2e-27 95.9 0.0 4.4e-27 94.1 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) YycH PF07435.6 EMR63567.1 - 0.03 13.0 0.1 0.042 12.5 0.1 1.1 1 0 0 1 1 1 0 YycH protein FAD_binding_2 PF00890.19 EMR63568.1 - 9.5e-86 288.2 0.7 1.2e-85 287.9 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EMR63568.1 - 5.4e-21 74.1 0.4 1.1e-19 69.9 0.0 3.2 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EMR63568.1 - 1.5e-12 47.0 3.2 1.6e-11 43.7 2.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EMR63568.1 - 1.5e-10 40.7 0.6 6e-10 38.7 0.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR63568.1 - 3.2e-09 36.9 0.0 2.4e-07 30.8 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR63568.1 - 5e-08 32.8 3.0 1.1e-07 31.6 0.4 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMR63568.1 - 5.3e-05 22.4 1.1 0.0094 15.0 0.4 2.6 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 EMR63568.1 - 0.00018 20.1 4.2 0.0087 14.5 0.2 3.2 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.14 EMR63568.1 - 0.00049 19.2 3.2 0.0017 17.5 2.2 1.8 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EMR63568.1 - 0.00079 18.6 0.2 0.27 10.2 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase GIDA PF01134.17 EMR63568.1 - 0.00081 18.3 2.8 0.1 11.4 1.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EMR63568.1 - 0.00094 18.9 0.6 0.0086 15.8 0.2 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMR63568.1 - 0.031 14.3 3.0 0.066 13.2 1.3 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR63568.1 - 0.096 13.1 5.4 1.7 9.0 1.3 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR63569.1 - 3.4e-18 66.4 0.0 9.4e-18 65.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR63569.1 - 7.9e-12 44.1 0.0 1.3e-10 40.0 0.0 2.7 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMR63569.1 - 1.1e-09 38.1 0.2 4e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMR63569.1 - 0.006 16.3 0.3 0.32 10.7 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMR63569.1 - 0.013 14.4 0.0 0.056 12.3 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EMR63569.1 - 0.021 13.7 0.0 0.66 8.8 0.0 2.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase SAS4 PF15460.1 EMR63570.1 - 4.5e-08 32.8 1.2 7.4e-08 32.1 0.1 2.0 1 1 1 2 2 2 1 Something about silencing, SAS, complex subunit 4 Nop14 PF04147.7 EMR63570.1 - 0.0022 16.0 19.1 0.0028 15.6 13.3 1.1 1 0 0 1 1 1 1 Nop14-like family MCPVI PF02993.9 EMR63570.1 - 0.042 13.9 1.7 0.062 13.4 1.2 1.3 1 0 0 1 1 1 0 Minor capsid protein VI TFIIF_alpha PF05793.7 EMR63570.1 - 0.043 12.1 17.0 0.055 11.8 11.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_primase_lrg PF04104.9 EMR63570.1 - 0.051 12.8 0.5 0.067 12.4 0.4 1.2 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit BUD22 PF09073.5 EMR63570.1 - 0.13 11.3 18.4 0.17 10.8 12.7 1.3 1 0 0 1 1 1 0 BUD22 TMEM51 PF15345.1 EMR63570.1 - 0.22 11.1 5.2 0.35 10.5 3.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Ycf1 PF05758.7 EMR63570.1 - 0.28 8.8 4.3 0.29 8.7 3.0 1.1 1 0 0 1 1 1 0 Ycf1 Daxx PF03344.10 EMR63570.1 - 0.28 9.6 19.4 0.36 9.2 13.5 1.2 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 EMR63570.1 - 0.56 9.2 21.3 0.84 8.7 14.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pox_Ag35 PF03286.9 EMR63570.1 - 0.63 9.5 17.5 0.56 9.6 9.4 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein TFIIA PF03153.8 EMR63570.1 - 4.8 6.9 18.6 7 6.4 12.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MscS_TM PF12794.2 EMR63570.1 - 4.9 5.6 5.5 6.8 5.1 3.8 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2146 PF10220.4 EMR63570.1 - 8.1 4.2 8.5 9.7 4.0 5.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) MIP PF00230.15 EMR63571.1 - 6.1e-45 153.4 12.7 7.2e-45 153.1 8.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.11 EMR63572.1 - 9.1e-14 50.9 4.8 1.1e-13 50.7 3.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily 2TM PF13239.1 EMR63572.1 - 0.095 12.7 0.3 0.34 10.9 0.2 2.1 1 1 0 1 1 1 0 2TM domain DUF3129 PF11327.3 EMR63573.1 - 2e-57 194.0 5.2 2e-57 194.0 3.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3129) CENP-B_dimeris PF09026.5 EMR63573.1 - 0.001 19.2 3.0 0.001 19.2 2.1 1.7 2 0 0 2 2 2 1 Centromere protein B dimerisation domain Myc_N PF01056.13 EMR63573.1 - 0.0031 16.7 3.2 0.0051 16.0 2.2 1.4 1 0 0 1 1 1 1 Myc amino-terminal region PBP1_TM PF14812.1 EMR63573.1 - 0.0033 17.7 2.8 0.0033 17.7 1.9 2.0 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 EMR63573.1 - 0.048 11.7 7.9 0.063 11.3 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 EMR63573.1 - 0.25 11.0 10.6 0.42 10.2 7.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.8 EMR63573.1 - 0.53 9.8 6.8 0.88 9.1 4.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EMR63573.1 - 0.72 9.3 9.5 1.3 8.5 6.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 EMR63573.1 - 2.2 6.1 15.0 2.9 5.7 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 EMR63573.1 - 2.9 7.5 5.1 6.5 6.4 3.6 1.6 1 0 0 1 1 1 0 FAM176 family Endonuclease_NS PF01223.18 EMR63574.1 - 6.8e-60 202.2 0.0 8.6e-60 201.9 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Chitin_synth_2 PF03142.10 EMR63578.1 - 3.2e-42 144.6 5.2 1.4e-32 112.7 1.4 2.0 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EMR63578.1 - 4.8e-09 36.1 5.0 7.9e-09 35.5 3.5 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EMR63578.1 - 4e-07 29.8 0.0 0.0062 16.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EMR63578.1 - 8.7e-05 22.4 0.2 0.0055 16.5 0.1 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_hydro_18 PF00704.23 EMR63579.1 - 4.5e-62 210.5 0.0 5.1e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 E_Pc_C PF06752.7 EMR63579.1 - 0.0027 17.2 0.4 0.0044 16.5 0.2 1.2 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus DUF3115 PF11312.3 EMR63579.1 - 0.044 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) Metallophos PF00149.23 EMR63582.1 - 6.8e-06 25.6 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMR63582.1 - 0.0054 16.5 0.0 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sugar_tr PF00083.19 EMR63583.1 - 3.5e-86 289.5 17.0 4.1e-86 289.3 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR63583.1 - 2e-22 79.3 33.7 7.2e-18 64.4 7.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR63583.1 - 0.00016 20.0 2.9 0.00034 18.9 2.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UDPG_MGDP_dh_N PF03721.9 EMR63584.1 - 2.7e-23 82.3 0.0 1.5e-21 76.6 0.0 2.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EMR63584.1 - 5.2e-19 68.2 0.0 1.1e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.10 EMR63584.1 - 5.8e-06 26.2 0.0 9.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.10 EMR63584.1 - 3.5e-05 23.9 0.0 9.5e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Methyltransf_18 PF12847.2 EMR63584.1 - 0.00018 22.0 0.0 0.0017 18.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain TrkA_N PF02254.13 EMR63584.1 - 0.00043 20.2 0.0 0.0027 17.6 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain Methyltransf_25 PF13649.1 EMR63584.1 - 0.0016 18.7 0.0 0.0038 17.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR63584.1 - 0.0024 18.3 0.0 0.0073 16.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.13 EMR63584.1 - 0.0074 15.9 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EMR63584.1 - 0.016 15.6 0.0 0.074 13.4 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EMR63584.1 - 0.037 12.9 0.1 9.5 5.0 0.0 2.6 3 0 0 3 3 3 0 Saccharopine dehydrogenase Methyltransf_12 PF08242.7 EMR63584.1 - 0.093 13.2 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Semialdhyde_dh PF01118.19 EMR63584.1 - 0.12 12.6 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Anp1 PF03452.9 EMR63585.1 - 3.6e-23 82.0 0.0 5.3e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Anp1 FAD_binding_4 PF01565.18 EMR63586.1 - 5.2e-21 74.5 1.0 9.6e-21 73.7 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR63586.1 - 0.0069 16.2 0.1 0.018 14.9 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like HALZ PF02183.13 EMR63587.1 - 0.022 14.4 1.9 0.043 13.5 1.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Sulfatase_C PF14707.1 EMR63587.1 - 0.27 11.5 1.7 0.42 10.9 0.2 1.8 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase DUF3106 PF11304.3 EMR63587.1 - 0.53 10.7 7.7 0.58 10.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DUF904 PF06005.7 EMR63587.1 - 1 9.6 6.6 0.31 11.3 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Fzo_mitofusin PF04799.8 EMR63587.1 - 1.2 8.5 4.7 5.3 6.3 3.2 1.8 1 1 0 1 1 1 0 fzo-like conserved region DivIC PF04977.10 EMR63587.1 - 1.8 8.1 7.6 0.35 10.4 0.9 2.1 2 0 0 2 2 2 0 Septum formation initiator Atg14 PF10186.4 EMR63587.1 - 1.8 7.4 6.6 2.6 6.9 4.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 EMR63587.1 - 4.2 7.7 5.1 3.6 7.9 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) GOLGA2L5 PF15070.1 EMR63587.1 - 5.5 5.3 10.3 0.22 9.9 1.6 1.9 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Cation_efflux PF01545.16 EMR63588.1 - 3.2e-18 65.8 9.7 1.4e-16 60.4 1.2 2.1 2 0 0 2 2 2 2 Cation efflux family AAA_12 PF13087.1 EMR63589.1 - 4.9e-54 182.7 0.0 6.9e-54 182.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMR63589.1 - 3.8e-41 141.2 0.2 1.6e-20 73.7 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 EMR63589.1 - 7.7e-13 48.4 0.0 4.7e-12 45.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMR63589.1 - 1.1e-11 44.2 0.0 2.6e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EMR63589.1 - 1.2e-06 28.1 0.3 0.14 11.6 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EMR63589.1 - 5.4e-05 22.9 0.0 0.00013 21.7 0.0 1.7 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 EMR63589.1 - 0.0003 20.2 0.0 0.00056 19.3 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 EMR63589.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MobB PF03205.9 EMR63589.1 - 0.0018 17.9 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.9 EMR63589.1 - 0.0019 17.2 0.1 0.02 13.8 0.0 2.0 1 1 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.1 EMR63589.1 - 0.0019 18.1 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.18 EMR63589.1 - 0.0082 15.5 0.4 0.024 14.0 0.2 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 EMR63589.1 - 0.0088 15.4 0.0 0.022 14.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EMR63589.1 - 0.01 15.2 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain RuvB_N PF05496.7 EMR63589.1 - 0.025 13.6 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 EMR63589.1 - 0.032 13.1 0.0 0.077 11.9 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EMR63589.1 - 0.042 14.0 0.3 0.28 11.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EMR63589.1 - 0.043 13.2 0.1 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 EMR63589.1 - 0.052 13.7 0.1 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMR63589.1 - 0.064 12.9 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EMR63589.1 - 0.073 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_33 PF13671.1 EMR63589.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EMR63589.1 - 0.089 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein DUF853 PF05872.7 EMR63589.1 - 0.095 11.0 0.1 0.15 10.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) UvrD_C PF13361.1 EMR63589.1 - 0.15 11.4 0.0 16 4.8 0.0 2.7 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain DUF21 PF01595.15 EMR63590.1 - 7.8e-32 110.0 0.0 1.2e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EMR63590.1 - 5.3e-06 26.1 0.5 0.022 14.5 0.0 2.8 2 0 0 2 2 2 2 CBS domain GP40 PF11025.3 EMR63590.1 - 0.013 15.1 1.5 0.028 14.0 1.1 1.5 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Fungal_trans PF04082.13 EMR63592.1 - 2.1e-05 23.5 0.0 7.2e-05 21.7 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EMR63593.1 - 2e-26 92.4 0.0 3e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain COX15-CtaA PF02628.10 EMR63594.1 - 2e-95 319.1 10.2 2.5e-95 318.8 7.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Zip PF02535.17 EMR63595.1 - 6.7e-48 163.3 0.8 8.9e-48 162.9 0.6 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Chromo_shadow PF01393.14 EMR63596.1 - 1e-12 47.6 0.0 2.6e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Chromo shadow domain Chromo PF00385.19 EMR63596.1 - 1.7e-09 37.2 0.8 1.7e-09 37.2 0.6 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AT_hook PF02178.14 EMR63596.1 - 0.092 12.4 0.7 0.25 11.1 0.5 1.8 1 0 0 1 1 1 0 AT hook motif Glyco_hydro_16 PF00722.16 EMR63597.1 - 6.2e-43 146.2 7.8 6.2e-43 146.2 5.4 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF2135 PF09906.4 EMR63597.1 - 0.18 11.7 1.2 0.98 9.4 0.8 2.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) Mitofilin PF09731.4 EMR63597.1 - 1.9 7.0 10.3 2.5 6.6 7.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ApbA_C PF08546.6 EMR63598.1 - 5.9e-27 94.1 0.0 1.3e-26 92.9 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EMR63598.1 - 5e-11 42.2 0.0 9.2e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lactonase PF10282.4 EMR63599.1 - 1.1e-19 70.7 0.0 1.5e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HisKA PF00512.20 EMR63600.1 - 2.5e-12 46.5 0.6 1e-11 44.6 0.4 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.21 EMR63600.1 - 9.2e-11 41.4 0.1 1.9e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMR63600.1 - 2.3e-10 40.4 0.0 3.8e-09 36.5 0.0 2.9 2 1 0 2 2 2 1 Response regulator receiver domain PAS_2 PF08446.6 EMR63600.1 - 4.3e-08 33.5 0.0 1.5e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 PAS fold GAF PF01590.21 EMR63600.1 - 0.00024 21.2 0.0 0.00053 20.1 0.0 1.6 1 0 0 1 1 1 1 GAF domain PAS_9 PF13426.1 EMR63600.1 - 0.014 15.7 0.0 0.05 13.9 0.0 1.9 1 0 0 1 1 1 0 PAS domain HATPase_c_3 PF13589.1 EMR63600.1 - 0.12 12.0 0.1 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dioxygenase_C PF00775.16 EMR63601.1 - 9.7e-49 165.0 0.0 1.3e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EMR63601.1 - 9.2e-10 38.3 0.1 1.6e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EMR63601.1 - 0.0026 17.7 0.0 0.0096 15.9 0.0 2.0 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Na_H_Exchanger PF00999.16 EMR63602.1 - 1e-17 63.7 21.8 2.5e-13 49.3 11.4 2.1 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family DUF4083 PF13314.1 EMR63602.1 - 6.6 6.6 6.1 1.3 8.9 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) RNB PF00773.14 EMR63604.1 - 2.9e-94 315.9 0.1 5e-94 315.2 0.0 1.4 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EMR63604.1 - 3e-10 40.3 0.5 1.7e-09 37.8 0.2 2.5 2 1 0 2 2 2 1 PIN domain OB_RNB PF08206.6 EMR63604.1 - 0.031 13.7 0.2 0.14 11.6 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain Trs65 PF12735.2 EMR63605.1 - 3e-58 197.5 0.0 6.3e-57 193.2 0.0 2.7 3 1 0 3 3 3 1 TRAPP trafficking subunit Trs65 Sigma70_ner PF04546.8 EMR63605.1 - 0.1 12.1 4.0 0.19 11.3 2.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 EMR63605.1 - 0.58 9.9 2.8 1.1 9.0 1.9 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 EMR63605.1 - 4.3 6.8 10.0 8.7 5.8 6.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin SIR2 PF02146.12 EMR63606.1 - 4.6e-27 94.8 0.0 1.2e-26 93.5 0.0 1.7 1 1 0 1 1 1 1 Sir2 family Dicty_REP PF05086.7 EMR63606.1 - 2.3 5.8 6.8 3 5.5 4.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_hydro_72 PF03198.9 EMR63607.1 - 6e-37 127.3 0.0 7e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EMR63607.1 - 0.09 11.9 0.0 0.33 10.1 0.0 1.7 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Phytase PF02333.10 EMR63607.1 - 0.092 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Phytase CRC_subunit PF08624.5 EMR63608.1 - 3.4e-55 185.7 0.0 4.9e-55 185.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit SNF2_N PF00176.18 EMR63609.1 - 1.7e-65 220.7 0.1 7.6e-65 218.6 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 EMR63609.1 - 3.6e-26 90.5 6.2 4e-15 55.2 0.1 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EMR63609.1 - 9.2e-14 51.0 0.0 2.6e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Med16 PF11635.3 EMR63610.1 - 5.8e-57 193.2 0.0 1.6e-33 115.6 0.0 3.1 1 1 2 3 3 3 3 Mediator complex subunit 16 Imm48 PF15587.1 EMR63610.1 - 0.022 14.1 0.1 0.045 13.1 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 48 ABC_tran PF00005.22 EMR63611.1 - 2e-31 109.1 0.0 5.4e-15 55.8 0.0 2.5 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 EMR63611.1 - 2.8e-14 52.4 5.9 2.8e-14 52.4 4.1 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EMR63611.1 - 2.7e-11 43.9 2.9 0.02 14.9 0.0 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EMR63611.1 - 6.5e-09 35.3 0.5 0.00017 20.9 0.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EMR63611.1 - 2.7e-06 28.2 0.1 0.055 14.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EMR63611.1 - 7.9e-06 26.1 0.0 0.098 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Fer4 PF00037.22 EMR63611.1 - 9.2e-06 25.0 2.7 9.2e-06 25.0 1.9 2.6 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_15 PF13175.1 EMR63611.1 - 1.2e-05 24.6 0.1 2.5 7.0 0.0 4.0 5 0 0 5 5 5 2 AAA ATPase domain AAA_29 PF13555.1 EMR63611.1 - 1.2e-05 24.6 0.4 0.064 12.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 EMR63611.1 - 1.3e-05 25.3 0.0 0.0075 16.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR63611.1 - 1.7e-05 24.9 0.0 0.0059 16.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMR63611.1 - 7.9e-05 21.8 0.9 0.53 9.4 0.0 3.2 4 0 0 4 4 4 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EMR63611.1 - 0.00013 22.3 0.1 0.0078 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMR63611.1 - 0.00019 21.4 0.4 0.067 13.1 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain UPF0079 PF02367.12 EMR63611.1 - 0.00021 20.9 0.3 0.0024 17.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EMR63611.1 - 0.00021 20.7 0.0 0.1 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EMR63611.1 - 0.00028 20.5 1.3 0.033 13.8 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EMR63611.1 - 0.00043 19.9 1.3 0.061 12.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Fer4_21 PF14697.1 EMR63611.1 - 0.00056 19.7 11.0 0.0011 18.8 7.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain RNA_helicase PF00910.17 EMR63611.1 - 0.00069 19.7 0.0 0.32 11.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase VirE PF05272.6 EMR63611.1 - 0.00082 18.8 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E Fer4_6 PF12837.2 EMR63611.1 - 0.0019 17.9 11.7 0.0065 16.2 1.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_5 PF07728.9 EMR63611.1 - 0.0033 17.1 0.2 0.13 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.12 EMR63611.1 - 0.0033 16.8 0.2 1.4 8.2 0.0 3.1 3 0 0 3 3 3 1 Thymidylate kinase Fer4_7 PF12838.2 EMR63611.1 - 0.0041 17.4 6.4 0.0059 16.9 0.2 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_33 PF13671.1 EMR63611.1 - 0.0049 16.7 0.0 0.34 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EMR63611.1 - 0.0062 15.9 2.9 0.13 11.6 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NB-ARC PF00931.17 EMR63611.1 - 0.011 14.6 0.0 2.7 6.7 0.0 2.4 3 0 0 3 3 2 0 NB-ARC domain AAA_13 PF13166.1 EMR63611.1 - 0.011 14.1 1.3 0.015 13.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.10 EMR63611.1 - 0.012 14.2 0.0 0.069 11.8 0.0 1.9 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 EMR63611.1 - 0.016 15.1 0.3 0.96 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMR63611.1 - 0.017 14.7 0.1 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EMR63611.1 - 0.018 15.5 0.0 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein SbcCD_C PF13558.1 EMR63611.1 - 0.04 13.8 0.0 13 5.7 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 EMR63611.1 - 0.052 13.0 2.1 0.32 10.4 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_16 PF13484.1 EMR63611.1 - 0.062 14.0 0.1 0.062 14.0 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 EMR63611.1 - 0.086 12.8 7.5 0.29 11.2 5.4 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain KaiC PF06745.8 EMR63611.1 - 0.12 11.4 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 EMR63611.1 - 0.13 12.1 1.6 9.2 6.1 0.0 3.1 2 2 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EMR63611.1 - 0.14 11.8 2.6 3.2 7.4 0.1 2.5 2 0 0 2 2 2 0 NTPase ArgK PF03308.11 EMR63611.1 - 0.21 10.3 0.2 1.5 7.5 0.0 2.0 2 0 0 2 2 2 0 ArgK protein AAA_19 PF13245.1 EMR63611.1 - 0.25 11.1 1.2 0.6 9.8 0.0 2.2 2 0 0 2 2 1 0 Part of AAA domain AAA_24 PF13479.1 EMR63611.1 - 0.48 9.9 2.8 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_10 PF13237.1 EMR63611.1 - 0.8 9.5 15.5 0.029 14.1 1.2 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EMR63611.1 - 1.4 9.0 12.0 0.21 11.5 1.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.1 EMR63611.1 - 1.5 9.1 13.6 0.071 13.3 1.6 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain FF PF01846.14 EMR63612.1 - 3.1e-52 174.2 12.9 5.8e-13 48.5 0.1 6.6 6 0 0 6 6 6 6 FF domain WW PF00397.21 EMR63612.1 - 3.6e-18 65.0 15.8 2.4e-10 40.0 3.9 2.6 2 0 0 2 2 2 2 WW domain Rick_17kDa_Anti PF05433.10 EMR63613.1 - 0.071 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycine zipper 2TM domain Lamp PF01299.12 EMR63613.1 - 1.7 7.6 5.8 3 6.8 4.0 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Abhydrolase_3 PF07859.8 EMR63614.1 - 1.7e-09 37.5 0.0 2.4e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1241 PF06840.6 EMR63615.1 - 0.0041 16.3 0.3 0.013 14.7 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1241) Baculo_PEP_C PF04513.7 EMR63615.1 - 0.015 15.1 0.3 0.53 10.1 0.0 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 EMR63615.1 - 0.023 12.0 5.7 0.029 11.7 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-C4H2 PF10146.4 EMR63615.1 - 0.037 14.0 2.6 0.067 13.2 1.8 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein ADIP PF11559.3 EMR63615.1 - 0.14 12.0 3.2 0.24 11.3 2.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Cytochrom_B562 PF07361.6 EMR63615.1 - 0.22 11.9 2.8 0.54 10.6 1.4 2.0 1 1 0 1 1 1 0 Cytochrome b562 PROL5-SMR PF15621.1 EMR63615.1 - 0.26 11.7 3.9 0.55 10.6 2.7 1.5 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family RRN3 PF05327.6 EMR63615.1 - 0.36 8.8 2.2 0.48 8.4 1.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1664 PF07889.7 EMR63615.1 - 0.4 10.4 2.5 0.66 9.7 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Nup88 PF10168.4 EMR63615.1 - 0.51 8.1 2.8 0.79 7.4 1.9 1.3 1 0 0 1 1 1 0 Nuclear pore component Atg14 PF10186.4 EMR63615.1 - 0.92 8.3 4.9 1.4 7.8 3.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EMR63615.1 - 0.93 8.0 5.2 1.2 7.6 3.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EMR63615.1 - 1.3 8.6 4.0 2.1 7.8 2.8 1.4 1 0 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 EMR63615.1 - 2.5 8.1 6.9 13 5.8 1.7 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BCS1_N PF08740.6 EMR63617.1 - 2.9e-50 170.4 1.0 2.9e-50 170.4 0.7 2.2 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 EMR63617.1 - 2.6e-16 60.0 0.0 8.5e-08 32.4 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMR63617.1 - 0.00011 21.9 0.0 0.002 17.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMR63617.1 - 0.0019 18.2 0.1 0.0081 16.1 0.0 2.0 1 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EMR63617.1 - 0.0079 15.6 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMR63617.1 - 0.024 13.6 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMR63617.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 EMR63617.1 - 0.044 12.8 0.0 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.1 EMR63617.1 - 0.045 13.9 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMR63617.1 - 0.051 13.4 0.0 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EMR63617.1 - 0.1 13.4 0.0 0.1 13.4 0.0 3.2 3 1 0 3 3 2 0 AAA domain NARP1 PF12569.3 EMR63617.1 - 0.56 8.8 25.0 1.1 7.9 17.3 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_11 PF13086.1 EMR63617.1 - 1.1 8.8 15.9 9.2 5.7 11.0 2.2 1 1 0 1 1 1 0 AAA domain U79_P34 PF03064.11 EMR63617.1 - 1.5 8.3 16.3 3.6 7.0 11.3 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RNase_H2-Ydr279 PF09468.5 EMR63617.1 - 2.3 7.3 16.6 5.4 6.1 11.5 1.7 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Spore_coat_CotO PF14153.1 EMR63617.1 - 3.7 6.9 23.3 12 5.3 16.1 1.9 1 0 0 1 1 1 0 Spore coat protein CotO TAF4 PF05236.9 EMR63617.1 - 8.2 5.6 22.5 78 2.3 16.0 2.2 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family XAP5 PF04921.9 EMR63618.1 - 0.0056 16.2 0.8 0.0064 16.0 0.6 1.0 1 0 0 1 1 1 1 XAP5, circadian clock regulator DNA_pol_alpha_N PF12254.3 EMR63618.1 - 0.051 13.3 0.4 0.081 12.7 0.3 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Glyco_tranf_2_3 PF13641.1 EMR63620.1 - 0.022 14.5 0.0 0.027 14.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Nop14 PF04147.7 EMR63620.1 - 6.8 4.4 23.6 8 4.2 16.3 1.0 1 0 0 1 1 1 0 Nop14-like family CorA PF01544.13 EMR63621.1 - 0.028 13.4 0.1 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HMG_CoA_synt_C PF08540.5 EMR63622.1 - 7e-104 347.2 0.8 8.7e-104 346.9 0.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EMR63622.1 - 6.5e-95 315.5 0.4 9.1e-95 315.1 0.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal zf-MYND PF01753.13 EMR63623.1 - 1.9e-09 37.2 9.8 4.7e-09 35.9 6.8 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EMR63623.1 - 0.77 9.4 7.2 1.9 8.2 5.0 1.7 1 0 0 1 1 1 0 HIT zinc finger Suc_Fer-like PF06999.7 EMR63624.1 - 3.9e-34 118.6 0.0 1.1e-33 117.1 0.0 1.7 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Opiods_neuropep PF01160.13 EMR63624.1 - 0.6 9.9 2.6 0.37 10.5 0.4 1.7 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide PfkB PF00294.19 EMR63625.1 - 1.1e-21 77.2 0.0 8.6e-21 74.3 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF4340 PF14238.1 EMR63626.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4340) Epimerase PF01370.16 EMR63627.1 - 1.8e-12 47.2 0.2 3.6e-12 46.2 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR63627.1 - 7.4e-06 25.0 0.2 0.0025 16.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 EMR63627.1 - 4.4e-05 22.8 0.1 7.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EMR63627.1 - 0.00014 22.1 0.0 0.00027 21.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EMR63627.1 - 0.00027 19.7 0.1 0.052 12.2 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMR63627.1 - 0.0041 17.1 0.0 0.0067 16.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EMR63627.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus mTERF PF02536.9 EMR63627.1 - 0.18 10.3 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 mTERF NAD_kinase PF01513.16 EMR63628.1 - 8.9e-65 218.2 0.0 9.9e-34 116.4 0.0 2.3 1 1 0 2 2 2 2 ATP-NAD kinase Glyco_hydro_72 PF03198.9 EMR63629.1 - 4.5e-119 397.1 2.2 6.2e-119 396.6 1.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EMR63629.1 - 3.1e-23 82.0 1.6 8.9e-23 80.5 1.1 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 EMR63629.1 - 0.0014 17.6 0.1 0.003 16.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Arg_repressor_C PF02863.13 EMR63629.1 - 0.099 12.1 0.3 0.49 9.9 0.1 2.1 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain Cyanate_lyase PF02560.9 EMR63630.1 - 5.8e-24 83.4 0.0 9e-24 82.8 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.17 EMR63630.1 - 0.00098 18.9 0.1 0.0015 18.3 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix Sigma70_r4_2 PF08281.7 EMR63630.1 - 0.0019 17.6 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_26 PF13443.1 EMR63630.1 - 0.021 15.0 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Sigma70_r4 PF04545.11 EMR63630.1 - 0.041 13.2 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 UreF PF01730.11 EMR63630.1 - 0.045 13.8 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 UreF HTH_19 PF12844.2 EMR63630.1 - 0.083 12.9 0.1 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain adh_short PF00106.20 EMR63631.1 - 3.8e-19 69.2 3.0 2.8e-18 66.4 2.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMR63631.1 - 6e-08 32.9 1.7 2.2e-06 27.7 0.2 2.2 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EMR63631.1 - 1.5e-05 24.6 3.5 2.5e-05 24.0 0.8 2.4 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMR63631.1 - 9.6e-05 22.2 0.4 0.00055 19.7 0.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR63631.1 - 0.0015 17.9 0.4 0.0036 16.7 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMR63631.1 - 0.0078 15.9 0.1 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1402 PF07182.6 EMR63631.1 - 0.016 14.0 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1402) RmlD_sub_bind PF04321.12 EMR63631.1 - 0.035 12.9 0.3 0.055 12.3 0.2 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 EMR63631.1 - 0.041 13.1 1.1 0.14 11.3 0.3 2.1 2 1 0 2 2 2 0 NmrA-like family Radical_SAM PF04055.16 EMR63632.1 - 9.1e-16 58.4 0.0 2.6e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EMR63632.1 - 6.9e-11 42.0 0.0 1.6e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family UQ_con PF00179.21 EMR63633.1 - 3.2e-26 91.4 0.0 6e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EMR63633.1 - 0.00056 19.5 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 UEV domain GFO_IDH_MocA PF01408.17 EMR63634.1 - 9.2e-23 81.0 0.0 1.9e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMR63634.1 - 1.1e-10 41.3 0.0 1.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EMR63634.1 - 0.021 15.0 0.0 0.059 13.6 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EMR63634.1 - 0.035 14.4 0.0 0.09 13.1 0.0 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF1213 PF06740.7 EMR63635.1 - 0.67 10.1 0.1 0.67 10.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1213) MT0933_antitox PF14013.1 EMR63635.1 - 9.9 6.3 10.1 0.73 9.9 3.1 2.1 2 1 0 2 2 2 0 MT0933-like antitoxin protein RNB PF00773.14 EMR63636.1 - 8.3e-72 242.2 0.0 1.6e-71 241.2 0.0 1.5 1 0 0 1 1 1 1 RNB domain Helicase_C PF00271.26 EMR63637.1 - 3.3e-12 46.0 0.1 8e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EMR63637.1 - 3.6e-12 46.1 0.0 1e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMR63637.1 - 4.9e-11 42.5 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 EMR63637.1 - 5.1e-10 39.1 0.4 1.2e-09 37.8 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMR63637.1 - 2.8e-05 24.2 0.1 7.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 EMR63637.1 - 0.00078 19.2 0.1 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 EMR63637.1 - 0.0031 17.3 0.0 0.44 10.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1424 PF07232.6 EMR63637.1 - 0.092 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative rep protein (DUF1424) 2-Hacid_dh_C PF02826.14 EMR63638.1 - 6.8e-51 171.9 0.0 1e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMR63638.1 - 7.5e-16 57.8 0.0 1.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMR63638.1 - 0.0015 18.3 0.0 0.0061 16.4 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Amidohydro_2 PF04909.9 EMR63639.1 - 2.5e-42 145.3 0.1 3e-42 145.0 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 EMR63639.1 - 0.18 10.9 0.0 0.44 9.7 0.0 1.7 1 1 0 1 1 1 0 TatD related DNase UQ_con PF00179.21 EMR63640.1 - 4.8e-42 142.7 0.0 6.3e-42 142.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EMR63640.1 - 8.1e-07 28.5 0.6 1.4e-06 27.8 0.4 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain RWD PF05773.17 EMR63640.1 - 0.033 14.0 0.1 0.057 13.3 0.1 1.5 1 1 0 1 1 1 0 RWD domain ATP-synt_ab PF00006.20 EMR63641.1 - 1.6e-113 377.4 0.0 2.3e-113 377.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMR63641.1 - 5.4e-18 65.5 0.3 1.1e-17 64.5 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMR63641.1 - 3.6e-14 52.7 4.3 7.8e-14 51.6 1.8 2.5 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain NAD_kinase PF01513.16 EMR63642.1 - 6.1e-51 172.8 0.0 2e-50 171.1 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase TIMELESS PF04821.9 EMR63643.1 - 1.7e-89 299.6 0.2 1.7e-89 299.6 0.1 3.1 4 0 0 4 4 4 1 Timeless protein TIMELESS_C PF05029.8 EMR63643.1 - 4.9e-32 111.6 41.4 4.9e-32 111.6 28.7 3.3 2 1 0 2 2 2 1 Timeless protein C terminal region PBP1_TM PF14812.1 EMR63643.1 - 0.13 12.5 0.2 0.13 12.5 0.1 7.1 5 2 2 7 7 7 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Acyltransferase PF01553.16 EMR63644.1 - 1e-21 76.7 0.0 1.6e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ank_4 PF13637.1 EMR63645.1 - 0.019 15.4 0.0 0.038 14.5 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMR63645.1 - 0.1 12.9 0.0 0.14 12.5 0.0 1.3 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Abhydrolase_6 PF12697.2 EMR63646.1 - 2.4e-31 109.3 6.4 2.8e-31 109.1 4.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR63646.1 - 6.2e-13 48.8 0.0 6.6e-11 42.2 0.0 2.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR63646.1 - 4.5e-12 45.9 0.1 2.7e-11 43.4 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMR63646.1 - 1.3e-09 37.7 0.1 3.1e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_C80 PF11713.3 EMR63647.1 - 0.06 13.1 0.1 0.073 12.8 0.0 1.0 1 0 0 1 1 1 0 Peptidase C80 family TruB_N PF01509.13 EMR63649.1 - 2.2e-44 151.2 0.0 4.8e-44 150.1 0.0 1.5 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TROVE PF05731.6 EMR63649.1 - 0.0038 16.0 0.0 0.0058 15.4 0.0 1.2 1 0 0 1 1 1 1 TROVE domain EXOSC1 PF10447.4 EMR63650.1 - 4.9e-30 103.3 0.7 9.7e-30 102.3 0.5 1.5 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EMR63650.1 - 3.6e-13 48.5 0.1 7.1e-13 47.6 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Sec2p PF06428.6 EMR63650.1 - 9.4e-11 41.4 1.7 1.8e-10 40.5 1.2 1.5 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p S1 PF00575.18 EMR63650.1 - 0.036 14.1 0.3 0.25 11.4 0.2 2.1 1 1 0 1 1 1 0 S1 RNA binding domain Cupin_1 PF00190.17 EMR63651.1 - 6.9e-12 45.0 0.1 1.9e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EMR63651.1 - 0.0038 16.6 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 1 Cupin domain ERG2_Sigma1R PF04622.7 EMR63652.1 - 4.5e-96 320.2 0.0 5.1e-96 320.0 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Nop14 PF04147.7 EMR63653.1 - 0.036 12.0 9.9 0.048 11.5 6.9 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EMR63653.1 - 8.7 5.4 19.6 2.2 7.4 10.7 1.8 2 0 0 2 2 2 0 NOA36 protein Metallophos PF00149.23 EMR63654.1 - 1.3e-14 54.0 0.5 2.4e-14 53.1 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMR63654.1 - 5.2e-06 26.3 0.0 1.1e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Syntaxin-6_N PF09177.6 EMR63655.1 - 1.4e-24 86.3 1.0 6.8e-24 84.1 0.0 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EMR63655.1 - 2.1e-11 43.3 2.9 2.1e-11 43.3 2.0 3.0 3 0 0 3 3 3 1 SNARE domain FlxA PF14282.1 EMR63655.1 - 0.0028 17.5 2.3 0.0028 17.5 1.6 2.4 2 0 0 2 2 2 1 FlxA-like protein Cwf_Cwc_15 PF04889.7 EMR63655.1 - 0.011 15.4 6.9 0.019 14.6 4.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Lectin_N PF03954.9 EMR63655.1 - 0.019 14.3 0.2 0.019 14.3 0.2 2.1 3 0 0 3 3 2 0 Hepatic lectin, N-terminal domain Daxx PF03344.10 EMR63655.1 - 0.042 12.3 10.9 0.057 11.9 7.6 1.2 1 0 0 1 1 1 0 Daxx Family BRF1 PF07741.8 EMR63655.1 - 0.23 11.6 3.6 0.12 12.6 0.9 1.7 2 0 0 2 2 2 0 Brf1-like TBP-binding domain AATF-Che1 PF13339.1 EMR63655.1 - 0.8 9.8 9.0 1.9 8.6 3.2 2.8 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor COG2 PF06148.6 EMR63655.1 - 2.7 7.8 7.3 3 7.7 1.8 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc24 PF08286.6 EMR63655.1 - 3.3 7.4 8.6 5.5 6.7 1.5 3.1 2 2 0 2 2 2 0 Spc24 subunit of Ndc80 TBCA PF02970.11 EMR63655.1 - 4.7 7.3 7.4 0.48 10.5 0.1 2.9 3 1 0 3 3 3 0 Tubulin binding cofactor A ACT_7 PF13840.1 EMR63656.1 - 1.2e-21 76.0 0.3 7e-17 60.7 0.0 2.5 2 0 0 2 2 2 2 ACT domain Glyco_hydro_43 PF04616.9 EMR63658.1 - 2.7e-40 138.2 7.1 3e-40 138.1 4.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Methyltransf_32 PF13679.1 EMR63659.1 - 2.9e-20 72.3 0.0 6e-20 71.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR63659.1 - 0.045 14.3 0.1 0.16 12.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DNA_ligase_A_M PF01068.16 EMR63660.1 - 7.1e-14 51.6 0.5 5.6e-09 35.6 0.1 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain GILT PF03227.11 EMR63660.1 - 0.018 14.8 0.2 0.13 12.1 0.1 2.3 2 0 0 2 2 2 0 Gamma interferon inducible lysosomal thiol reductase (GILT) TSSC4 PF15264.1 EMR63660.1 - 0.13 12.7 0.1 0.3 11.5 0.1 1.7 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 Ribosomal_L35p PF01632.14 EMR63660.1 - 0.27 11.1 2.0 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L35 DUF4048 PF13257.1 EMR63661.1 - 1.2e-20 74.2 29.7 4.2e-20 72.4 9.4 3.0 3 1 1 4 4 4 2 Domain of unknown function (DUF4048) 3HCDH_N PF02737.13 EMR63662.1 - 2.5e-51 173.9 2.3 6.7e-51 172.4 1.6 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EMR63662.1 - 3.2e-33 113.9 0.0 6.5e-33 113.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EMR63662.1 - 0.00016 21.5 0.8 0.00041 20.2 0.6 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 EMR63662.1 - 0.0002 20.4 0.3 0.00025 20.1 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DAO PF01266.19 EMR63662.1 - 0.0036 16.2 0.1 0.0048 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EMR63662.1 - 0.0065 16.2 0.7 0.016 14.9 0.4 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EMR63662.1 - 0.015 14.7 0.3 0.059 12.8 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EMR63662.1 - 0.026 13.6 0.2 0.069 12.2 0.1 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EMR63662.1 - 0.11 12.9 2.4 0.66 10.4 1.7 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent K_channel_TID PF07941.6 EMR63662.1 - 7 6.9 7.6 10 6.4 1.2 2.8 2 1 1 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain ATG22 PF11700.3 EMR63663.1 - 4.4e-122 407.9 25.7 5.1e-122 407.7 17.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like SHOCT PF09851.4 EMR63663.1 - 0.13 11.7 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Short C-terminal domain HupH_C PF04809.8 EMR63663.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region GLE1 PF07817.8 EMR63665.1 - 1.6e-24 86.2 0.0 2.1e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 GLE1-like protein NUDIX PF00293.23 EMR63666.1 - 4.7e-15 55.4 0.1 7.1e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Ferritin_2 PF13668.1 EMR63667.1 - 1.3e-39 135.2 0.1 2.3e-39 134.4 0.1 1.4 1 0 0 1 1 1 1 Ferritin-like domain PP2C PF00481.16 EMR63668.1 - 2.8e-61 207.1 0.4 1.4e-49 168.8 0.1 3.9 3 1 1 4 4 4 3 Protein phosphatase 2C Cation_efflux PF01545.16 EMR63669.1 - 8.2e-27 93.9 2.1 1.1e-26 93.5 1.4 1.1 1 0 0 1 1 1 1 Cation efflux family p450 PF00067.17 EMR63670.1 - 1.4e-31 109.5 0.0 1.8e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EMR63671.1 - 1e-08 35.0 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR63671.1 - 1.6e-07 31.0 0.0 4.7e-07 29.5 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR63671.1 - 6.5e-06 26.7 0.0 1.3e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR63671.1 - 5.2e-05 23.6 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR63671.1 - 0.0014 18.9 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR63671.1 - 0.0026 17.8 0.0 0.0068 16.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMR63671.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMR63671.1 - 0.019 15.4 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HlyC PF02794.11 EMR63671.1 - 0.04 13.5 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 RTX toxin acyltransferase family FtsJ PF01728.14 EMR63671.1 - 0.042 13.8 0.0 0.42 10.5 0.0 2.1 1 1 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EMR63671.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Snf7 PF03357.16 EMR63672.1 - 1.3e-34 119.0 19.0 1.3e-34 119.0 13.2 1.3 1 1 0 1 1 1 1 Snf7 CaMBD PF02888.11 EMR63672.1 - 0.0066 16.2 3.1 0.0066 16.2 2.2 2.0 1 1 1 2 2 2 1 Calmodulin binding domain V_ATPase_I PF01496.14 EMR63672.1 - 0.037 11.9 3.3 0.045 11.6 2.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ist1 PF03398.9 EMR63672.1 - 0.1 11.9 6.6 0.18 11.2 4.6 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DFF40 PF09230.5 EMR63672.1 - 2.3 7.5 5.6 2.6 7.3 3.5 1.2 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa Hpt PF01627.18 EMR63672.1 - 4.9 7.2 7.1 3.6 7.6 1.7 2.6 1 1 1 2 2 2 0 Hpt domain adh_short PF00106.20 EMR63673.1 - 1.4e-16 60.9 2.3 9.8e-15 54.8 1.6 2.2 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMR63673.1 - 0.0009 19.2 1.4 0.002 18.1 0.8 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR63673.1 - 0.0011 18.4 0.1 0.083 12.3 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.5 EMR63673.1 - 0.0025 17.5 0.3 0.027 14.1 0.1 2.2 2 0 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.12 EMR63673.1 - 0.069 12.0 0.1 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Ank_2 PF12796.2 EMR63674.1 - 4.4e-11 42.9 0.0 3.5e-10 40.0 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMR63674.1 - 1.4e-10 40.4 3.3 7.6e-07 28.6 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat NACHT PF05729.7 EMR63674.1 - 1.8e-09 37.4 0.1 7.1e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 EMR63674.1 - 4.1e-09 35.7 0.0 7.3e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Ank_4 PF13637.1 EMR63674.1 - 3.3e-08 33.8 0.7 1.7e-07 31.5 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR63674.1 - 1.7e-07 31.2 0.1 5.8e-07 29.5 0.0 2.1 2 0 0 2 2 1 1 Ankyrin repeats (many copies) AAA_16 PF13191.1 EMR63674.1 - 7.2e-07 29.3 0.0 9.6e-06 25.7 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.1 EMR63674.1 - 1.4e-05 24.8 0.3 0.0011 18.9 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat AAA PF00004.24 EMR63674.1 - 0.0076 16.4 0.0 0.14 12.3 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EMR63674.1 - 0.01 16.0 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EMR63674.1 - 0.041 14.0 0.0 0.19 11.8 0.0 2.2 2 1 0 2 2 1 0 AAA domain RuvB_N PF05496.7 EMR63674.1 - 0.084 11.9 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus OPT PF03169.10 EMR63677.1 - 6.3e-11 41.4 1.2 7.2e-11 41.2 0.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NRPS PF08415.5 EMR63677.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Nonribosomal peptide synthase peroxidase PF00141.18 EMR63678.1 - 9.3e-29 100.5 3.0 4.3e-28 98.3 2.0 1.8 1 1 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 EMR63678.1 - 2.4e-05 24.0 0.0 5.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) zf-FPG_IleRS PF06827.9 EMR63679.1 - 0.11 12.1 0.2 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS DUF676 PF05057.9 EMR63680.1 - 3.3e-45 154.0 0.0 6.1e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EMR63680.1 - 0.0023 17.5 0.0 0.0045 16.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EMR63680.1 - 0.0041 16.8 0.0 0.011 15.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMR63680.1 - 0.0063 16.1 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF4536 PF15055.1 EMR63681.1 - 3.6e-05 23.7 1.7 5.6e-05 23.1 1.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) SPT16 PF08644.6 EMR63682.1 - 1.4e-56 190.5 0.2 1.4e-56 190.5 0.1 3.0 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EMR63682.1 - 2.7e-50 170.0 1.0 2.7e-50 170.0 0.7 2.2 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EMR63682.1 - 1e-22 80.7 0.0 1.8e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EMR63682.1 - 1.1e-22 79.8 0.0 3.3e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Toprim_3 PF13362.1 EMR63682.1 - 0.065 13.4 0.0 0.32 11.2 0.0 2.2 1 0 0 1 1 1 0 Toprim domain TPR_12 PF13424.1 EMR63683.1 - 0.00096 19.0 2.1 0.008 16.1 0.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMR63683.1 - 0.003 17.4 0.9 0.32 10.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat MARVEL PF01284.18 EMR63684.1 - 9.8e-23 80.5 15.2 1.2e-22 80.3 10.6 1.0 1 0 0 1 1 1 1 Membrane-associating domain MpPF26 PF07666.6 EMR63684.1 - 0.044 13.6 4.1 0.062 13.1 1.3 2.2 2 1 0 2 2 2 0 M penetrans paralogue family 26 HhH-GPD PF00730.20 EMR63685.1 - 1.5e-16 60.6 0.0 2.6e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EMR63685.1 - 4.5e-08 32.3 0.0 1.1e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SUR7 PF06687.7 EMR63686.1 - 5.4e-23 81.6 9.9 7.9e-23 81.1 6.9 1.3 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EMR63686.1 - 3.9e-05 23.4 5.7 3.9e-05 23.4 3.9 2.0 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PNTB PF02233.11 EMR63686.1 - 0.024 13.4 3.6 0.042 12.6 2.5 1.3 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit RseC_MucC PF04246.7 EMR63686.1 - 0.026 14.0 6.1 0.06 12.9 1.2 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC RCR PF12273.3 EMR63686.1 - 0.13 12.7 0.2 0.13 12.7 0.2 1.9 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF4064 PF13273.1 EMR63686.1 - 0.25 11.4 8.6 0.14 12.2 1.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Trp_oprn_chp PF09534.5 EMR63686.1 - 0.25 10.9 10.2 0.19 11.3 4.3 2.3 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2207 PF09972.4 EMR63686.1 - 0.58 8.6 4.5 8.7 4.7 3.1 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.1 EMR63686.1 - 0.66 10.4 3.3 27 5.2 0.0 3.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain zf-DHHC PF01529.15 EMR63686.1 - 1.1 8.6 4.0 3.7 6.9 1.8 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase TFIIA PF03153.8 EMR63687.1 - 0.73 9.6 9.3 1 9.1 6.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4267 PF14087.1 EMR63688.1 - 6.6e-15 54.6 0.5 8e-15 54.4 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Pkinase PF00069.20 EMR63689.1 - 1.6e-31 109.4 2.4 2.2e-31 108.9 1.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR63689.1 - 1.8e-16 60.0 0.6 2.3e-16 59.6 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMR63689.1 - 0.00029 20.6 0.0 0.0042 16.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMR63689.1 - 0.0019 17.8 2.1 0.0061 16.1 1.2 2.0 1 1 1 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 EMR63689.1 - 0.025 13.9 0.3 0.047 13.0 0.0 1.5 2 0 0 2 2 2 0 RIO1 family ADH_N PF08240.7 EMR63690.1 - 5.9e-23 80.7 3.1 9.8e-23 79.9 2.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR63690.1 - 6.4e-20 71.0 0.3 1.2e-19 70.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EMR63690.1 - 0.012 16.2 0.1 0.027 15.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PBP1_TM PF14812.1 EMR63691.1 - 0.045 14.0 1.1 0.045 14.0 0.7 3.4 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2146 PF10220.4 EMR63691.1 - 5.5 4.8 6.1 9.6 4.0 4.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) TPR_11 PF13414.1 EMR63692.1 - 5.8e-08 32.2 0.2 0.0026 17.3 0.0 2.8 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EMR63692.1 - 2e-05 24.1 0.0 1.6 8.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMR63692.1 - 0.0001 21.7 0.1 0.61 9.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMR63692.1 - 0.0044 17.6 0.0 3.2 8.5 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMR63692.1 - 0.01 16.3 0.0 1.5 9.6 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMR63692.1 - 0.029 14.1 0.2 9 6.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 EMR63692.1 - 0.047 13.4 1.7 0.43 10.4 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMR63692.1 - 0.048 14.1 1.4 2.9 8.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMR63692.1 - 0.071 13.0 0.2 2.6 8.0 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat GSDH PF07995.6 EMR63693.1 - 1.8e-06 27.2 0.2 9e-05 21.7 0.4 2.9 2 2 0 2 2 2 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 EMR63693.1 - 3.6e-05 23.2 0.0 0.012 15.0 0.0 3.0 2 1 1 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region SBBP PF06739.6 EMR63693.1 - 0.00055 19.6 0.0 1.3 8.8 0.0 2.8 2 0 0 2 2 2 2 Beta-propeller repeat NHL PF01436.16 EMR63693.1 - 0.019 14.9 0.0 20 5.3 0.0 4.0 3 1 0 3 3 3 0 NHL repeat Glyco_hydro_43 PF04616.9 EMR63694.1 - 2.8e-61 207.1 2.9 3.6e-61 206.7 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sigma70_ner PF04546.8 EMR63695.1 - 0.081 12.5 0.2 0.081 12.5 0.1 3.4 2 1 1 3 3 3 0 Sigma-70, non-essential region BBE PF08031.7 EMR63696.1 - 0.002 17.9 0.5 0.0044 16.9 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like Caps_synth PF05704.7 EMR63697.1 - 2.6e-19 69.4 0.8 4.1e-19 68.8 0.5 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EMR63697.1 - 1.1e-05 25.7 0.0 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif GHMP_kinases_N PF00288.21 EMR63698.1 - 5.1e-16 58.5 1.1 5.1e-16 58.5 0.8 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMR63698.1 - 2.4e-06 27.6 0.0 1.6e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal Pkinase PF00069.20 EMR63699.1 - 2.6e-21 75.9 0.0 5.7e-21 74.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR63699.1 - 3.3e-12 46.0 0.0 2.9e-10 39.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EMR63699.1 - 0.024 13.4 0.0 0.053 12.3 0.0 1.5 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase 7tm_6 PF02949.15 EMR63699.1 - 0.17 10.6 0.1 0.29 9.9 0.1 1.3 1 0 0 1 1 1 0 7tm Odorant receptor MCM PF00493.18 EMR63700.1 - 2.3e-134 447.4 0.2 3.8e-134 446.6 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMR63700.1 - 1.4e-16 61.1 0.1 3.5e-15 56.5 0.0 2.7 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMR63700.1 - 9.6e-08 31.4 0.0 9.9e-07 28.1 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EMR63700.1 - 0.00031 20.2 0.0 0.00071 19.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EMR63700.1 - 0.00061 19.4 0.3 0.0054 16.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMR63700.1 - 0.02 14.6 0.0 0.054 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AA_permease PF00324.16 EMR63701.1 - 1.2e-12 47.0 3.5 1.5e-12 46.6 2.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR63701.1 - 8e-07 27.9 6.1 5.2e-06 25.2 4.1 1.9 1 1 1 2 2 2 1 Amino acid permease FLgD_tudor PF13861.1 EMR63701.1 - 0.11 12.5 0.1 3.1 7.8 0.0 2.2 2 0 0 2 2 2 0 FlgD Tudor-like domain Bax1-I PF01027.15 EMR63701.1 - 0.2 11.2 7.2 0.36 10.4 5.0 1.3 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Aminotran_1_2 PF00155.16 EMR63702.1 - 2.9e-08 33.0 0.0 3.2e-06 26.3 0.0 3.2 2 1 0 2 2 2 1 Aminotransferase class I and II MOZ_SAS PF01853.13 EMR63703.1 - 1.8e-84 281.7 0.6 2.7e-84 281.1 0.4 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EMR63703.1 - 1.9e-16 59.4 0.1 7.3e-16 57.6 0.0 2.1 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 EMR63703.1 - 0.068 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR63703.1 - 0.097 12.8 0.0 0.27 11.4 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Adenylsucc_synt PF00709.16 EMR63704.1 - 1.6e-75 254.3 0.1 2.2e-65 221.0 0.0 2.7 2 1 1 3 3 3 2 Adenylosuccinate synthetase RNase_T PF00929.19 EMR63704.1 - 1.6e-24 87.0 0.0 2.9e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Exonuclease RNase_H2_suC PF08615.6 EMR63705.1 - 3.3e-10 39.9 0.0 3.8e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Ferric_reduct PF01794.14 EMR63706.1 - 2.2e-20 73.0 13.6 2.2e-20 73.0 9.4 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EMR63706.1 - 5.4e-12 45.8 0.0 9.3e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMR63706.1 - 1.4e-10 40.9 0.0 2.5e-09 36.9 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EMR63706.1 - 0.0019 18.7 0.0 3 8.4 0.0 2.4 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain Ribosomal_60s PF00428.14 EMR63706.1 - 0.027 14.8 3.3 0.066 13.6 2.3 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein PTP_N PF12453.3 EMR63706.1 - 0.03 13.9 0.1 0.088 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal Nop53 PF07767.6 EMR63707.1 - 7.2e-102 341.2 27.6 8.9e-102 340.9 19.1 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF16 PF01519.11 EMR63707.1 - 8.3 6.6 14.4 1.5e+04 -3.9 10.0 3.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 EthD PF07110.6 EMR63708.1 - 1.7e-09 38.4 0.5 2.3e-09 38.0 0.3 1.2 1 0 0 1 1 1 1 EthD domain PASTA PF03793.14 EMR63709.1 - 1.3 8.7 8.4 12 5.5 0.1 3.3 3 0 0 3 3 3 0 PASTA domain BTK PF00779.14 EMR63710.1 - 0.0025 17.3 4.9 0.0051 16.3 3.4 1.6 1 0 0 1 1 1 1 BTK motif BTV_NS2 PF04514.7 EMR63710.1 - 7.3 5.3 15.0 10 4.9 10.1 1.4 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Borrelia_P83 PF05262.6 EMR63710.1 - 8.5 4.5 19.2 11 4.1 13.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ras PF00071.17 EMR63712.1 - 4.6e-42 143.1 0.1 5.8e-42 142.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EMR63712.1 - 7.3e-12 44.8 0.5 9.5e-12 44.4 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EMR63712.1 - 5e-11 43.1 0.1 1.2e-10 41.9 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EMR63712.1 - 7.1e-07 28.8 0.0 9.4e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMR63712.1 - 0.0046 16.1 0.1 0.0061 15.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region zf-RING_2 PF13639.1 EMR63713.1 - 2.6e-10 39.9 3.8 1.1e-08 34.7 1.8 3.0 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMR63713.1 - 8.6e-07 28.5 3.8 2.8e-05 23.6 0.2 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMR63713.1 - 1.4e-06 28.3 2.3 2.5e-06 27.4 0.3 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMR63713.1 - 5.2e-06 26.3 0.2 5.2e-06 26.3 0.1 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR63713.1 - 0.00024 20.7 1.0 0.00024 20.7 0.7 2.8 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMR63713.1 - 0.00051 19.6 0.2 0.00051 19.6 0.1 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMR63713.1 - 0.0022 17.8 0.2 0.0022 17.8 0.1 3.3 5 0 0 5 5 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EMR63713.1 - 0.0055 16.5 5.8 0.018 14.9 1.7 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 EMR63713.1 - 0.022 14.5 2.7 2 8.2 0.0 3.0 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_UBOX PF13445.1 EMR63713.1 - 0.031 14.0 0.0 0.031 14.0 0.0 2.8 2 1 1 3 3 2 0 RING-type zinc-finger zf-RING_3 PF14369.1 EMR63713.1 - 0.044 13.7 2.9 6.2 6.9 0.4 2.9 2 0 0 2 2 2 0 zinc-finger Pellino PF04710.9 EMR63713.1 - 0.064 11.8 1.0 0.16 10.6 0.1 1.8 1 1 1 2 2 2 0 Pellino zf-RING_4 PF14570.1 EMR63713.1 - 0.22 11.1 6.1 4.7 6.8 0.3 2.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ribbon_3 PF13248.1 EMR63713.1 - 1.6 8.0 7.6 3.6 6.9 0.1 3.2 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EMR63713.1 - 2.9 7.5 7.1 9.6 5.8 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain HET PF06985.6 EMR63714.1 - 0.069 13.3 0.3 0.28 11.3 0.2 2.0 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EMR63716.1 - 1.4e-16 60.1 26.2 1.7e-16 59.8 18.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily COX2-transmemb PF09125.5 EMR63717.1 - 7.3 6.2 7.6 2.1 7.9 0.2 2.9 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane ETC_C1_NDUFA4 PF04800.7 EMR63718.1 - 2.6e-36 123.5 0.3 3.8e-36 122.9 0.2 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.4 EMR63719.1 - 1.1e-38 131.3 0.6 1.2e-38 131.2 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi FAD_binding_3 PF01494.14 EMR63720.1 - 6.1e-06 25.5 0.0 8.4e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMR63720.1 - 0.0013 18.6 0.1 0.0038 17.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR63720.1 - 0.026 13.4 0.5 0.039 12.8 0.4 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMR63720.1 - 0.027 14.2 0.0 0.35 10.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EMR63720.1 - 0.066 13.6 0.4 0.31 11.4 0.1 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR63720.1 - 0.1 11.4 0.0 0.26 10.1 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein DIT1_PvcA PF05141.7 EMR63721.1 - 1.1e-87 293.9 0.0 1.3e-87 293.7 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein RSS_P20 PF11757.3 EMR63721.1 - 0.027 14.5 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like PAP_assoc PF03828.14 EMR63722.1 - 1.9e-18 66.1 0.1 3.3e-17 62.1 0.0 2.7 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EMR63722.1 - 0.028 14.7 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Zip PF02535.17 EMR63722.1 - 0.28 10.1 0.2 0.45 9.4 0.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter RAP1 PF07218.6 EMR63723.1 - 2.2 6.2 10.8 2.9 5.8 7.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) p450 PF00067.17 EMR63724.1 - 4.5e-55 187.0 0.0 4.7e-54 183.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Cu-oxidase PF00394.17 EMR63725.1 - 3.5e-33 114.7 0.0 5.3e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMR63725.1 - 4.1e-19 68.4 0.8 1.3e-18 66.8 0.5 1.8 1 0 0 1 1 1 1 Multicopper oxidase WSC PF01822.14 EMR63726.1 - 3.6e-73 241.5 65.2 1.6e-20 72.7 9.6 4.1 4 0 0 4 4 4 4 WSC domain Cytomega_gL PF01801.11 EMR63726.1 - 0.046 13.2 2.3 27 4.1 0.0 3.1 3 0 0 3 3 3 0 Cytomegalovirus glycoprotein L HAD_2 PF13419.1 EMR63727.1 - 3.8e-06 27.2 0.1 0.058 13.6 0.0 2.4 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Prenyltrans_2 PF13249.1 EMR63727.1 - 0.0017 18.7 0.0 2.3 8.6 0.0 2.4 2 0 0 2 2 2 2 Prenyltransferase-like Hydrolase_like PF13242.1 EMR63727.1 - 0.033 13.8 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like NIR_SIR PF01077.17 EMR63728.1 - 5e-52 175.4 0.1 2.7e-46 156.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EMR63728.1 - 1.2e-29 101.7 0.1 2.2e-14 52.8 0.1 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EMR63728.1 - 1.8e-29 102.5 0.0 4.5e-29 101.2 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EMR63728.1 - 1.6e-09 37.5 0.0 9.2e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg UPRTase PF14681.1 EMR63729.1 - 7.4e-34 116.7 0.0 1.1e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Methyltransf_11 PF08241.7 EMR63730.1 - 1.1e-06 29.0 0.0 1.9e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR63730.1 - 0.032 13.3 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMR63731.1 - 0.00033 20.9 0.0 0.00061 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR63731.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ABM PF03992.11 EMR63732.1 - 0.00022 21.2 0.1 0.0003 20.7 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3733 PF12534.3 EMR63732.1 - 0.096 11.9 0.2 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 Rib_5-P_isom_A PF06026.9 EMR63733.1 - 3.5e-38 130.6 0.0 5.1e-37 126.8 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) FAD_binding_3 PF01494.14 EMR63734.1 - 2.3e-61 207.8 0.0 3.5e-61 207.2 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EMR63734.1 - 4.3e-08 32.4 1.0 7.1e-07 28.4 0.7 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EMR63734.1 - 3.8e-07 29.3 0.7 0.011 14.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR63734.1 - 6.6e-06 24.8 0.4 0.00031 19.3 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EMR63734.1 - 3.2e-05 24.0 0.1 0.00019 21.5 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR63734.1 - 0.00046 20.1 0.1 0.0015 18.4 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMR63734.1 - 0.00061 20.1 0.1 0.0086 16.4 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMR63734.1 - 0.0013 17.9 0.1 0.0039 16.3 0.0 2.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR63734.1 - 0.0071 16.2 0.1 0.025 14.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR63734.1 - 0.02 13.9 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EMR63734.1 - 0.038 12.8 0.2 0.067 12.0 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Pantoate_ligase PF02569.10 EMR63735.1 - 2.2e-81 272.7 0.0 4.5e-81 271.6 0.0 1.5 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase TENA_THI-4 PF03070.11 EMR63736.1 - 4e-06 26.7 3.0 0.012 15.4 0.2 2.1 2 0 0 2 2 2 2 TENA/THI-4/PQQC family Bud13 PF09736.4 EMR63737.1 - 1.3e-36 126.0 1.5 1.3e-36 126.0 1.0 2.4 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DUF4010 PF13194.1 EMR63737.1 - 0.2 10.9 2.6 0.15 11.3 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) DUF2229 PF09989.4 EMR63737.1 - 1.6 8.1 3.3 2.9 7.3 2.3 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Pyr_redox_2 PF07992.9 EMR63738.1 - 2.2e-22 79.9 0.0 3.2e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR63738.1 - 3.7e-12 46.4 0.0 3.1e-10 40.3 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EMR63738.1 - 1.1e-06 27.5 0.5 2.3e-06 26.4 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EMR63738.1 - 5.6e-05 23.2 0.1 0.00014 21.9 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMR63738.1 - 0.00016 21.2 0.9 0.00016 21.2 0.6 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EMR63738.1 - 0.00018 20.6 2.2 0.00042 19.5 1.5 1.6 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.1 EMR63738.1 - 0.019 15.0 0.0 1.4 8.9 0.0 2.5 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR63738.1 - 0.042 12.6 0.1 0.74 8.5 0.1 2.7 3 0 0 3 3 3 0 FAD binding domain Methyltransf_23 PF13489.1 EMR63739.1 - 0.00013 21.7 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain HET PF06985.6 EMR63740.1 - 1.1e-29 103.3 5.2 1.1e-29 103.3 3.6 3.5 2 2 0 2 2 2 1 Heterokaryon incompatibility protein (HET) ORC6 PF05460.8 EMR63740.1 - 0.0026 16.9 12.4 0.0042 16.2 8.6 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Trep_Strep PF09605.5 EMR63740.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF2146 PF10220.4 EMR63740.1 - 0.67 7.8 7.9 0.99 7.3 5.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF2201_N PF13203.1 EMR63740.1 - 0.95 8.5 6.8 1.7 7.7 4.7 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain SR-25 PF10500.4 EMR63740.1 - 2.1 7.7 26.2 6 6.2 16.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MFS_1 PF07690.11 EMR63741.1 - 6e-29 100.8 45.3 2.8e-27 95.3 31.3 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR63741.1 - 9.1e-12 44.2 1.4 9.1e-12 44.2 1.0 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EMR63741.1 - 5e-06 25.0 20.6 1.1e-05 23.8 14.3 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TP_methylase PF00590.15 EMR63742.1 - 4.3e-19 69.0 0.0 6.9e-19 68.3 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases V-ATPase_H_N PF03224.9 EMR63743.1 - 0.022 13.9 0.2 0.12 11.4 0.1 1.9 2 0 0 2 2 2 0 V-ATPase subunit H Glyco_transf_90 PF05686.7 EMR63744.1 - 3.2e-12 45.8 0.1 4.1e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 90 DUF809 PF05663.6 EMR63744.1 - 0.0009 19.1 4.7 0.0017 18.3 3.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF809) Coatomer_WDAD PF04053.9 EMR63745.1 - 5.4e-170 565.9 0.0 3.2e-169 563.4 0.0 2.1 2 1 1 3 3 3 1 Coatomer WD associated region WD40 PF00400.27 EMR63745.1 - 5.9e-46 152.7 7.5 2e-10 40.1 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EMR63745.1 - 7.6e-05 21.0 2.5 0.014 13.5 0.7 3.5 2 1 1 3 3 3 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EMR63745.1 - 0.00063 19.4 0.0 0.92 9.3 0.0 3.6 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region NOA36 PF06524.7 EMR63745.1 - 6 6.0 4.8 8.6 5.5 3.3 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.14 EMR63745.1 - 7.9 6.9 12.4 11 6.5 7.8 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pkinase PF00069.20 EMR63746.1 - 2.4e-70 236.6 0.0 3e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR63746.1 - 4.6e-33 114.3 0.0 6.2e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EMR63746.1 - 1.5e-10 41.4 1.4 4.3e-10 39.9 1.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMR63746.1 - 0.00072 18.5 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMR63746.1 - 0.11 11.5 0.1 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 EMR63747.1 - 1.2e-18 67.3 0.0 4.4e-18 65.5 0.0 2.0 3 0 0 3 3 3 1 PAS domain RGS PF00615.14 EMR63747.1 - 1.4e-10 41.3 0.0 2.4e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS_4 PF08448.5 EMR63747.1 - 1.2e-07 31.7 0.0 2.1e-06 27.7 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.6 EMR63747.1 - 0.0041 17.1 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 PAS fold PAS PF00989.19 EMR63747.1 - 0.013 15.2 0.0 0.036 13.8 0.0 1.8 1 1 0 1 1 1 0 PAS fold Baculo_p74 PF04583.7 EMR63747.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae p74 conserved region AhpC-TSA PF00578.16 EMR63748.1 - 5.5e-39 132.6 0.0 7.4e-39 132.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMR63748.1 - 1e-13 51.0 0.0 1.4e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EMR63748.1 - 1.1e-12 47.3 0.0 2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin adh_short_C2 PF13561.1 EMR63749.1 - 1e-22 81.1 0.0 1.2e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR63749.1 - 1.9e-18 66.9 0.0 6e-18 65.3 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR63749.1 - 0.00022 20.9 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Pyridox_oxidase PF01243.15 EMR63751.1 - 3.4e-09 36.5 0.0 5.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Mannitol_dh_C PF08125.8 EMR63752.1 - 3.5e-46 157.3 0.1 5.3e-46 156.7 0.1 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EMR63752.1 - 7.8e-22 77.8 1.4 3.2e-21 75.8 0.0 2.4 3 0 0 3 3 3 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 EMR63752.1 - 0.021 14.2 0.4 0.051 12.9 0.2 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PGI PF00342.14 EMR63753.1 - 4.9e-121 404.5 0.1 5.7e-121 404.3 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase zf-C2H2_jaz PF12171.3 EMR63754.1 - 2.2e-06 27.6 0.1 3.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMR63754.1 - 5.1e-05 23.3 0.1 8.8e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 EMR63754.1 - 0.00014 21.7 12.6 0.00014 21.7 8.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-DBF PF07535.7 EMR63754.1 - 0.016 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 DBF zinc finger TFIIB PF00382.14 EMR63755.1 - 1.1e-38 130.9 2.4 1.4e-24 85.6 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EMR63755.1 - 2e-14 52.6 0.7 3.1e-14 52.0 0.5 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 EMR63755.1 - 0.0018 18.2 0.1 0.12 12.2 0.1 2.4 1 1 1 2 2 2 1 Cyclin, C-terminal domain HTH_Tnp_ISL3 PF13542.1 EMR63755.1 - 0.036 13.2 0.1 0.18 11.0 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 RB_B PF01857.15 EMR63755.1 - 0.07 12.6 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain HTH_5 PF01022.15 EMR63755.1 - 0.14 11.7 0.0 50 3.6 0.0 3.1 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family PHD PF00628.24 EMR63756.1 - 3.3e-08 33.0 10.0 5.2e-08 32.4 6.9 1.3 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 EMR63756.1 - 0.0071 15.6 4.4 0.013 14.7 3.0 1.4 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EMR63756.1 - 0.01 15.5 7.2 0.01 15.5 5.0 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EMR63756.1 - 0.039 13.2 10.6 0.26 10.6 7.4 2.2 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EMR63756.1 - 0.081 12.6 4.0 0.15 11.8 2.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Tnp_zf-ribbon_2 PF13842.1 EMR63756.1 - 0.72 10.3 7.6 0.7 10.3 2.9 2.2 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon SART-1 PF03343.8 EMR63757.1 - 0.00017 20.1 10.5 0.00021 19.8 7.3 1.1 1 0 0 1 1 1 1 SART-1 family LMBR1 PF04791.11 EMR63757.1 - 0.081 11.4 0.4 0.082 11.4 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Otopetrin PF03189.8 EMR63757.1 - 0.13 11.2 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 Otopetrin Med15 PF09606.5 EMR63757.1 - 0.36 8.9 27.6 0.43 8.7 19.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.11 EMR63757.1 - 1.5 8.6 3.6 1.8 8.4 2.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GvpL_GvpF PF06386.6 EMR63757.1 - 3.2 7.2 16.1 5.2 6.5 11.1 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Activator_LAG-3 PF11498.3 EMR63757.1 - 6.1 5.4 36.5 7.8 5.1 25.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SOBP PF15279.1 EMR63757.1 - 8.3 6.6 12.6 11 6.3 8.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein GMC_oxred_C PF05199.8 EMR63758.1 - 4.4e-09 36.7 0.0 7.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR63758.1 - 2.5e-08 33.4 0.1 6e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase CoA_transf_3 PF02515.12 EMR63759.1 - 2.3e-58 196.6 0.0 2.6e-57 193.1 0.0 2.1 2 0 0 2 2 2 1 CoA-transferase family III AA_permease_2 PF13520.1 EMR63760.1 - 1.2e-48 165.7 44.5 1.4e-48 165.4 30.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMR63760.1 - 4e-28 97.9 41.6 5.3e-28 97.6 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1356 PF07092.7 EMR63760.1 - 0.21 10.7 0.8 0.37 9.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) NARP1 PF12569.3 EMR63762.1 - 2.2e-193 643.7 22.1 4.6e-193 642.6 7.0 2.8 2 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 EMR63762.1 - 2.3e-20 72.6 27.9 0.0035 17.6 4.0 8.1 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 EMR63762.1 - 9.6e-20 70.7 33.3 5e-06 27.0 3.5 8.6 9 3 2 11 11 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 EMR63762.1 - 1.5e-17 63.0 28.7 1.9e-06 27.4 0.3 7.7 5 1 2 8 8 7 6 TPR repeat TPR_14 PF13428.1 EMR63762.1 - 4.3e-17 61.0 23.3 0.0027 18.1 0.0 10.4 7 4 4 11 11 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMR63762.1 - 6.3e-13 47.5 39.1 4.7e-05 22.9 0.2 11.4 12 1 0 12 12 11 3 Tetratricopeptide repeat TPR_9 PF13371.1 EMR63762.1 - 1.5e-12 47.1 16.1 0.00012 21.8 0.8 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMR63762.1 - 5.2e-10 38.4 26.1 3.4e-06 26.4 0.2 8.5 10 1 0 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMR63762.1 - 3.9e-09 36.0 16.0 0.24 11.7 0.0 10.1 10 1 1 11 11 11 1 Tetratricopeptide repeat Apc3 PF12895.2 EMR63762.1 - 3.7e-07 30.1 19.2 0.014 15.4 0.7 5.7 4 3 2 6 6 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EMR63762.1 - 3.6e-06 26.3 18.0 0.0049 16.5 0.0 7.2 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMR63762.1 - 8.8e-06 25.5 34.0 0.00086 19.2 0.2 7.5 5 3 3 8 8 7 3 Tetratricopeptide repeat TPR_15 PF13429.1 EMR63762.1 - 8.5e-05 21.7 22.0 0.042 12.9 0.9 5.4 3 2 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMR63762.1 - 0.00036 20.3 13.7 1.9 8.4 0.2 5.4 5 0 0 5 5 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 EMR63762.1 - 0.0013 18.3 15.5 1.4 8.9 0.0 7.4 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_3 PF07720.7 EMR63762.1 - 0.014 15.1 3.9 0.048 13.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMR63762.1 - 0.05 14.0 12.5 0.8 10.3 0.3 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMR63762.1 - 0.12 12.4 21.7 3.2 7.8 0.1 6.8 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMR63762.1 - 2.1 9.0 37.3 0.51 10.9 0.1 9.5 11 1 0 11 11 9 0 Tetratricopeptide repeat zf-GRF PF06839.7 EMR63763.1 - 3.7e-05 23.5 6.3 0.041 13.8 0.4 2.7 2 0 0 2 2 2 2 GRF zinc finger YrzO PF14142.1 EMR63763.1 - 0.14 11.8 0.2 0.31 10.6 0.2 1.5 1 0 0 1 1 1 0 YrzO-like protein DUF2454 PF10521.4 EMR63764.1 - 1.4e-61 207.9 0.0 2e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Peptidase_S8 PF00082.17 EMR63765.1 - 7.8e-43 146.6 0.0 2.5e-42 144.9 0.0 1.8 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EMR63765.1 - 2.6e-13 50.3 0.0 7.9e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EMR63765.1 - 0.0017 18.0 0.0 0.0054 16.3 0.0 1.9 1 0 0 1 1 1 1 PA domain MFS_1 PF07690.11 EMR63766.1 - 7.5e-33 113.6 39.4 7.5e-33 113.6 27.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR63766.1 - 1.5e-05 23.8 29.6 0.00053 18.6 20.6 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TPR_12 PF13424.1 EMR63767.1 - 1.7e-10 40.6 0.2 0.13 12.2 0.0 6.9 6 1 0 6 6 6 2 Tetratricopeptide repeat Suf PF05843.9 EMR63767.1 - 4.9e-09 36.3 8.0 0.1 12.3 1.8 6.0 3 2 2 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EMR63767.1 - 1.7e-07 31.2 15.2 0.89 10.3 0.0 10.3 9 3 4 13 13 12 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMR63767.1 - 3.5e-06 26.5 0.5 1.2 8.8 0.0 6.1 6 0 0 6 6 6 1 TPR repeat TPR_15 PF13429.1 EMR63767.1 - 1.2e-05 24.5 9.4 0.00024 20.2 1.2 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMR63767.1 - 2e-05 25.1 6.2 0.033 14.8 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EMR63767.1 - 2.7e-05 23.9 4.8 2.9 7.6 0.1 6.2 6 0 0 6 6 6 2 Mad3/BUB1 homology region 1 TPR_19 PF14559.1 EMR63767.1 - 0.001 19.3 0.4 22 5.5 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat NRDE-2 PF08424.5 EMR63767.1 - 0.0017 17.3 9.7 0.57 8.9 0.1 5.1 2 2 2 4 4 4 2 NRDE-2, necessary for RNA interference RPN7 PF10602.4 EMR63767.1 - 0.0018 17.7 1.6 0.033 13.5 0.2 3.3 3 2 0 3 3 3 1 26S proteasome subunit RPN7 TPR_8 PF13181.1 EMR63767.1 - 0.0021 17.7 3.4 1.7 8.5 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMR63767.1 - 0.046 13.6 15.4 11 6.2 0.0 6.8 8 0 0 8 8 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EMR63767.1 - 0.067 12.4 0.0 1.5 8.0 0.0 2.9 2 0 0 2 2 2 0 SHNi-TPR Pol_alpha_B_N PF08418.5 EMR63767.1 - 0.14 11.6 0.2 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal TPR_10 PF13374.1 EMR63767.1 - 0.58 10.1 4.3 79 3.3 0.5 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMR63767.1 - 1.4 9.4 4.9 69 4.2 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Sugar_tr PF00083.19 EMR63768.1 - 8e-45 153.2 16.7 2.1e-44 151.8 11.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR63768.1 - 1.8e-11 43.3 19.2 8.5e-11 41.1 13.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily PolyA_pol PF01743.15 EMR63769.1 - 1.4e-25 89.9 0.1 2.4e-25 89.1 0.1 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EMR63769.1 - 6.2e-07 28.9 0.0 1.3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EMR63769.1 - 8.2e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative ATP-synt_D PF01813.12 EMR63770.1 - 4.8e-31 107.8 4.5 3.3e-25 88.8 0.1 3.0 1 1 2 3 3 3 2 ATP synthase subunit D HisKA_3 PF07730.8 EMR63770.1 - 0.061 13.6 0.2 0.63 10.4 0.1 2.6 2 0 0 2 2 2 0 Histidine kinase RRN3 PF05327.6 EMR63770.1 - 0.18 9.8 3.3 0.24 9.4 2.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ribonuc_L-PSP PF01042.16 EMR63771.1 - 5.5e-21 74.5 0.0 6.8e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP FAD_binding_9 PF08021.6 EMR63771.1 - 0.0068 16.3 0.2 0.22 11.5 0.0 2.1 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain Pec_lyase_C PF00544.14 EMR63773.1 - 1.5e-19 70.2 2.5 2.2e-19 69.7 1.7 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EMR63773.1 - 0.00043 20.0 15.5 0.0033 17.1 10.8 2.2 1 1 0 1 1 1 1 Right handed beta helix region Syja_N PF02383.13 EMR63774.1 - 8.1e-91 304.0 0.0 1.7e-90 303.0 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain Mito_fiss_reg PF05308.6 EMR63774.1 - 0.28 10.5 13.9 0.08 12.2 7.0 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator Citrate_synt PF00285.16 EMR63776.1 - 4e-100 335.0 0.0 4.7e-100 334.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase DUF4360 PF14273.1 EMR63777.1 - 2.5e-69 232.6 4.4 2.8e-69 232.4 3.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MIP PF00230.15 EMR63778.1 - 2e-26 92.8 1.2 2.6e-26 92.4 0.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein Arch_ATPase PF01637.13 EMR63779.1 - 1.8e-06 27.8 0.1 3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EMR63779.1 - 1.9e-06 27.9 2.4 2.4e-05 24.4 0.7 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EMR63779.1 - 0.015 14.7 0.1 0.071 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EMR63779.1 - 0.018 14.5 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.8 EMR63779.1 - 0.05 12.5 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 EMR63779.1 - 0.074 13.1 0.6 0.23 11.6 0.4 1.8 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EMR63779.1 - 0.14 12.6 0.1 2.2 8.7 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein Med9 PF07544.8 EMR63780.1 - 0.091 12.5 0.5 0.18 11.5 0.3 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 NYD-SP28_assoc PF14775.1 EMR63780.1 - 4.6 7.0 6.4 0.63 9.7 0.2 2.5 3 0 0 3 3 3 0 Sperm tail C-terminal domain IF-2B PF01008.12 EMR63782.1 - 8e-45 152.9 0.0 1e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family RepL PF05732.6 EMR63782.1 - 0.025 13.7 0.0 0.05 12.8 0.0 1.5 1 1 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Transp_cyt_pur PF02133.10 EMR63783.1 - 4.2e-95 318.8 35.0 5.3e-95 318.5 24.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin adh_short PF00106.20 EMR63784.1 - 5.8e-12 45.8 0.5 1.6e-11 44.4 0.4 1.7 1 0 0 1 1 1 1 short chain dehydrogenase GMC_oxred_C PF05199.8 EMR63784.1 - 1.2e-10 41.7 0.1 1.1e-08 35.4 0.0 3.4 4 0 0 4 4 4 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR63784.1 - 1e-06 28.1 0.0 3.6e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMR63784.1 - 0.00026 19.9 0.3 0.0005 19.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_1 PF00561.15 EMR63784.1 - 0.00033 20.3 0.0 0.032 13.7 0.0 2.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold KR PF08659.5 EMR63784.1 - 0.00045 19.9 0.2 0.0012 18.5 0.1 1.7 1 0 0 1 1 1 1 KR domain NAD_binding_8 PF13450.1 EMR63784.1 - 0.015 15.2 0.7 0.048 13.6 0.5 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMR63784.1 - 0.092 11.8 0.4 0.14 11.2 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR63784.1 - 0.096 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF900 PF05990.7 EMR63784.1 - 0.17 11.2 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) GIDA PF01134.17 EMR63784.1 - 0.21 10.3 0.1 0.32 9.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Malic_M PF03949.10 EMR63785.1 - 3.8e-87 292.0 0.0 4.9e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EMR63785.1 - 7e-69 231.0 0.0 1.2e-68 230.3 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF3632 PF12311.3 EMR63786.1 - 1.6e-16 60.6 0.3 2.3e-16 60.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) ELFV_dehydrog PF00208.16 EMR63787.1 - 1.5e-29 103.3 0.1 1.6e-29 103.1 0.0 1.0 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Qn_am_d_aIV PF09100.5 EMR63787.1 - 0.014 15.0 0.1 0.017 14.8 0.1 1.2 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV Ras PF00071.17 EMR63788.1 - 2.1e-65 219.0 0.5 2.5e-65 218.7 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR63788.1 - 1.7e-21 76.9 0.0 2.5e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMR63788.1 - 3.4e-16 58.9 0.1 4.2e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMR63788.1 - 3.1e-05 23.2 0.1 4.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMR63788.1 - 4.7e-05 22.9 0.1 9.6e-05 21.8 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMR63788.1 - 0.0001 22.1 0.0 0.00022 21.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMR63788.1 - 0.00057 19.1 0.0 0.00086 18.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 EMR63788.1 - 0.0014 18.8 0.0 0.14 12.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR63788.1 - 0.0018 18.4 0.0 0.0032 17.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EMR63788.1 - 0.0051 16.0 0.0 0.033 13.4 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EMR63788.1 - 0.012 14.8 0.0 0.031 13.4 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 G-alpha PF00503.15 EMR63788.1 - 0.014 14.1 0.1 0.31 9.6 0.0 2.3 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 EMR63788.1 - 0.025 14.5 0.1 0.064 13.2 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EMR63788.1 - 0.034 14.0 0.2 0.11 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMR63788.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EMR63788.1 - 0.079 12.6 0.0 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TFIIE_beta PF02186.10 EMR63788.1 - 0.084 12.8 0.0 0.91 9.5 0.0 2.2 2 0 0 2 2 2 0 TFIIE beta subunit core domain ABC_tran PF00005.22 EMR63788.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter BUD22 PF09073.5 EMR63789.1 - 0.00091 18.4 5.7 0.0012 18.0 4.0 1.2 1 0 0 1 1 1 1 BUD22 SelP_N PF04592.9 EMR63789.1 - 0.0018 17.7 0.7 0.015 14.6 1.3 1.7 2 0 0 2 2 2 1 Selenoprotein P, N terminal region PBP1_TM PF14812.1 EMR63789.1 - 0.022 15.0 5.1 0.25 11.6 0.8 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Senescence_reg PF04520.8 EMR63789.1 - 0.082 13.4 2.8 0.23 11.9 1.7 1.8 2 0 0 2 2 2 0 Senescence regulator RP-C_C PF11800.3 EMR63789.1 - 0.12 12.0 0.9 0.17 11.5 0.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region BTV_NS2 PF04514.7 EMR63789.1 - 0.61 8.9 3.5 0.8 8.5 2.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RTA1 PF04479.8 EMR63790.1 - 1.5e-19 70.3 9.7 2.9e-19 69.4 6.7 1.4 1 0 0 1 1 1 1 RTA1 like protein F-box-like PF12937.2 EMR63790.1 - 0.00022 20.9 0.2 0.00056 19.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like p450 PF00067.17 EMR63792.1 - 2.7e-57 194.3 0.0 3.5e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C50 PF03568.12 EMR63792.1 - 0.2 10.2 0.0 0.77 8.3 0.0 1.7 2 0 0 2 2 2 0 Peptidase family C50 Metallothio_2 PF01439.13 EMR63792.1 - 0.93 10.0 9.8 1.4 9.5 6.1 1.8 2 0 0 2 2 2 0 Metallothionein RNA_pol_Rpb6 PF01192.17 EMR63793.1 - 1.9e-23 81.9 0.2 3.5e-23 81.0 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 SDA1 PF05285.7 EMR63793.1 - 0.14 11.3 7.7 0.18 11.0 5.4 1.1 1 0 0 1 1 1 0 SDA1 p450 PF00067.17 EMR63794.1 - 8.5e-35 120.1 0.0 1.2e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.21 EMR63795.1 - 4.1e-26 89.6 43.3 0.00017 21.7 0.1 10.4 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR63795.1 - 5.3e-23 79.6 46.5 0.00056 20.0 0.2 10.4 10 0 0 10 10 10 10 C2H2-type zinc finger zf-met PF12874.2 EMR63795.1 - 3.3e-09 36.6 2.5 0.37 11.0 0.0 6.3 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EMR63795.1 - 2.7e-08 33.6 13.4 0.00017 21.7 0.4 10.4 12 1 0 12 12 12 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMR63795.1 - 8.1e-07 29.0 27.6 0.18 11.9 1.0 9.6 10 0 0 10 10 10 3 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.7 EMR63795.1 - 0.011 15.3 1.4 0.17 11.5 0.3 2.8 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-H2C2_5 PF13909.1 EMR63795.1 - 5.3 7.4 41.8 0.71 10.2 0.5 9.5 9 1 1 10 10 10 0 C2H2-type zinc-finger domain Esterase PF00756.15 EMR63796.1 - 8.4e-53 179.3 0.0 9.7e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EMR63796.1 - 5.5e-07 29.4 0.0 7.4e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR63796.1 - 8.7e-06 25.7 0.1 1.6e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR63796.1 - 0.0093 15.1 0.1 0.02 14.1 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EMR63796.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EMR63796.1 - 0.022 13.6 0.0 0.039 12.8 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Esterase_phd PF10503.4 EMR63796.1 - 0.069 12.3 0.1 0.088 12.0 0.1 1.3 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.8 EMR63797.1 - 2.8e-21 76.0 0.2 2.8e-21 76.0 0.1 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR63797.1 - 2.7e-06 27.2 0.1 3e-06 27.0 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EMR63797.1 - 8.9e-06 25.3 0.0 1e-05 25.1 0.0 1.0 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EMR63797.1 - 4.7e-05 23.3 0.9 5.1e-05 23.2 0.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EMR63797.1 - 9e-05 22.8 0.0 0.00011 22.5 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 EMR63797.1 - 0.00025 20.3 0.0 0.00082 18.6 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EMR63797.1 - 0.00071 19.0 0.0 0.00074 19.0 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase LIP PF03583.9 EMR63797.1 - 0.0018 17.4 0.0 0.0022 17.2 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase Esterase PF00756.15 EMR63797.1 - 0.0029 17.0 0.0 0.0031 16.9 0.0 1.1 1 0 0 1 1 1 1 Putative esterase DUF2974 PF11187.3 EMR63797.1 - 0.0051 16.2 0.0 0.0052 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) AXE1 PF05448.7 EMR63797.1 - 0.011 14.2 0.0 0.011 14.2 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.20 EMR63797.1 - 0.014 15.0 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Lipase (class 3) Esterase_phd PF10503.4 EMR63797.1 - 0.021 14.0 0.2 0.028 13.6 0.1 1.5 1 1 0 1 1 1 0 Esterase PHB depolymerase DUF2048 PF09752.4 EMR63797.1 - 0.032 13.0 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DLH PF01738.13 EMR63797.1 - 0.036 13.3 0.0 0.045 13.0 0.0 1.3 1 1 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.6 EMR63797.1 - 0.086 12.5 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal VirJ PF06057.6 EMR63797.1 - 0.1 12.3 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) MFS_1 PF07690.11 EMR63798.1 - 9.6e-24 83.7 20.7 7.9e-17 60.9 4.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CPSF_A PF03178.10 EMR63798.1 - 0.045 12.8 0.0 0.12 11.3 0.0 1.6 1 1 0 1 1 1 0 CPSF A subunit region 2-Hacid_dh_C PF02826.14 EMR63799.1 - 5.3e-42 142.9 0.0 7e-42 142.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMR63799.1 - 3e-11 42.9 0.0 3.7e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMR63799.1 - 0.005 16.6 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMR63799.1 - 0.066 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Baculo_PEP_C PF04513.7 EMR63801.1 - 0.0041 16.9 0.7 2.2 8.1 0.0 3.3 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3357 PF11837.3 EMR63801.1 - 0.0045 16.8 3.0 6.1 6.7 0.0 3.6 4 0 0 4 4 4 2 Domain of unknown function (DUF3357) PAPA-1 PF04795.7 EMR63802.1 - 1.2e-25 90.0 2.9 1.2e-25 90.0 2.0 3.2 4 1 1 5 5 5 1 PAPA-1-like conserved region DUF1307 PF06998.6 EMR63803.1 - 0.018 15.0 7.1 1.2 9.2 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1307) NLE PF08154.7 EMR63803.1 - 0.089 12.8 2.1 22 5.1 0.0 3.2 3 0 0 3 3 3 0 NLE (NUC135) domain AraC_N PF06719.8 EMR63803.1 - 0.45 9.8 2.5 26 4.0 0.1 3.1 2 1 1 3 3 3 0 AraC-type transcriptional regulator N-terminus Mesd PF10185.4 EMR63803.1 - 8.8 5.9 19.7 4.8 6.8 0.4 3.2 3 0 0 3 3 3 0 Chaperone for wingless signalling and trafficking of LDL receptor Pex14_N PF04695.8 EMR63804.1 - 5.7e-18 65.2 3.8 5.7e-18 65.2 2.6 2.3 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RecX PF02631.11 EMR63804.1 - 0.016 15.4 0.6 0.028 14.6 0.4 1.4 1 0 0 1 1 1 0 RecX family FAP PF07174.6 EMR63804.1 - 2.2 7.4 16.2 0.91 8.7 7.8 2.1 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Gluconate_2-dh3 PF13618.1 EMR63805.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Methyltransf_23 PF13489.1 EMR63806.1 - 1.1e-15 57.7 0.0 1.5e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR63806.1 - 1.9e-11 44.4 0.0 3.6e-10 40.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR63806.1 - 2.4e-10 40.7 0.0 3e-09 37.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR63806.1 - 1.4e-09 37.7 0.0 9e-09 35.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR63806.1 - 4.9e-08 33.3 0.0 1e-07 32.3 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR63806.1 - 7.6e-06 26.2 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMR63806.1 - 0.0012 17.9 0.0 0.02 13.9 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EMR63806.1 - 0.0014 18.0 0.0 0.022 14.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EMR63806.1 - 0.0032 17.5 0.0 0.059 13.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMR63806.1 - 0.0046 16.0 0.0 0.0071 15.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EMR63806.1 - 0.013 15.4 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EMR63806.1 - 0.024 13.7 0.0 0.16 11.0 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family p450 PF00067.17 EMR63807.1 - 5.6e-70 236.1 0.0 7.2e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EMR63807.1 - 1.3e-29 103.2 0.1 2.1e-29 102.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EMR63807.1 - 1e-18 67.7 0.0 2.2e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EMR63807.1 - 1.7e-15 57.4 0.0 7.1e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain SIS_2 PF13580.1 EMR63807.1 - 0.07 12.8 0.1 1 9.0 0.0 2.7 3 0 0 3 3 3 0 SIS domain p450 PF00067.17 EMR63808.1 - 6.6e-63 212.8 0.0 1.4e-62 211.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Dicty_REP PF05086.7 EMR63808.1 - 0.14 9.8 2.7 0.2 9.4 1.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein VIT1 PF01988.14 EMR63808.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 VIT family FAD_binding_4 PF01565.18 EMR63809.1 - 1.8e-12 46.9 0.2 7.1e-11 41.7 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain adh_short PF00106.20 EMR63810.1 - 2.7e-17 63.1 2.4 2.4e-11 43.8 0.2 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EMR63810.1 - 1.1e-09 38.3 0.6 1.7e-08 34.5 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMR63810.1 - 1.7e-05 24.9 0.1 2.7e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR63810.1 - 9.8e-05 21.7 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.21 EMR63810.1 - 0.00053 19.5 0.0 0.00083 18.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1776 PF08643.5 EMR63810.1 - 0.00093 18.4 0.0 0.0019 17.3 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_2 PF03446.10 EMR63810.1 - 0.0012 18.7 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.10 EMR63810.1 - 0.0049 16.5 0.1 0.0071 15.9 0.1 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein F420_oxidored PF03807.12 EMR63810.1 - 0.0076 16.6 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EMR63810.1 - 0.024 14.3 0.1 0.055 13.1 0.1 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EMR63810.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EMR63810.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SET PF00856.23 EMR63811.1 - 0.0012 19.1 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 SET domain CtaG_Cox11 PF04442.9 EMR63812.1 - 1.3e-55 187.3 0.0 2.2e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 NAD_binding_8 PF13450.1 EMR63812.1 - 7.3e-12 45.1 0.0 1.8e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMR63812.1 - 1.3e-09 37.6 0.0 0.0019 17.3 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EMR63812.1 - 2.3e-05 24.5 0.0 0.0042 17.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR63812.1 - 0.00011 21.2 1.2 0.0021 17.0 0.8 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMR63812.1 - 0.0016 18.2 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMR63812.1 - 0.0067 16.3 0.0 0.06 13.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR63812.1 - 0.11 10.8 0.0 2.6 6.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Peptidase_S32 PF05579.8 EMR63814.1 - 0.0014 17.6 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Trypsin_2 PF13365.1 EMR63814.1 - 0.0069 16.3 0.1 0.093 12.7 0.0 2.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain RNase_H PF00075.19 EMR63815.1 - 3.8e-05 24.0 0.0 7.3e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 RNase H WD40 PF00400.27 EMR63816.1 - 2e-40 135.2 11.7 9.6e-09 34.8 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 EMR63816.1 - 3.1e-30 104.0 15.7 5.4e-30 103.2 10.9 1.4 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 EMR63816.1 - 9.3e-06 25.4 1.3 0.00016 21.4 0.2 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 EMR63816.1 - 1.6e-05 24.6 0.0 2.5 7.8 0.0 4.5 2 2 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 EMR63816.1 - 0.0022 16.8 5.1 0.14 10.8 0.0 3.6 1 1 0 3 3 3 1 Nup133 N terminal like PCI PF01399.22 EMR63817.1 - 2e-19 69.8 0.5 7.7e-19 67.9 0.0 2.2 3 0 0 3 3 3 1 PCI domain TPR_8 PF13181.1 EMR63817.1 - 4e-05 23.0 0.8 2.4 8.1 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat DDRGK PF09756.4 EMR63817.1 - 8.7e-05 22.0 0.1 0.00017 21.0 0.1 1.4 1 0 0 1 1 1 1 DDRGK domain TPR_7 PF13176.1 EMR63817.1 - 0.00081 19.0 1.4 5.5 7.0 0.3 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Med2 PF11214.3 EMR63817.1 - 0.016 15.2 2.3 0.064 13.2 0.0 2.9 3 1 0 3 3 3 0 Mediator complex subunit 2 TPR_1 PF00515.23 EMR63817.1 - 0.066 12.8 0.7 18 5.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2497 PF10691.4 EMR63817.1 - 0.083 12.8 0.2 0.64 10.0 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2497) TPR_2 PF07719.12 EMR63817.1 - 0.38 10.7 5.2 18 5.5 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMR63817.1 - 1.4 8.8 14.4 1.1 9.2 0.3 4.8 2 2 3 6 6 6 0 Tetratricopeptide repeat AMPKBI PF04739.10 EMR63818.1 - 1.2e-28 98.9 1.9 1.7e-28 98.4 0.6 1.9 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain FAM104 PF15434.1 EMR63819.1 - 0.38 10.9 10.6 0.29 11.3 4.6 2.3 2 0 0 2 2 2 0 Family 104 adh_short PF00106.20 EMR63820.1 - 2.5e-05 24.2 0.0 0.00024 21.0 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_8 PF13450.1 EMR63820.1 - 0.051 13.6 0.9 10 6.2 0.2 3.0 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 EMR63820.1 - 0.055 12.6 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OmdA PF13376.1 EMR63820.1 - 0.13 11.8 0.2 0.46 10.1 0.0 1.9 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Nop53 PF07767.6 EMR63820.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Activator_LAG-3 PF11498.3 EMR63821.1 - 0.0013 17.5 3.9 0.0018 17.1 2.7 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Red1 PF07964.6 EMR63821.1 - 0.023 12.8 7.8 0.029 12.5 5.4 1.1 1 0 0 1 1 1 0 Rec10 / Red1 DUF3523 PF12037.3 EMR63821.1 - 0.15 10.9 15.5 0.22 10.5 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Ycf1 PF05758.7 EMR63821.1 - 0.59 7.7 4.7 0.59 7.7 3.3 1.1 1 0 0 1 1 1 0 Ycf1 Macoilin PF09726.4 EMR63821.1 - 3.1 5.9 12.3 3.8 5.6 8.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Borrelia_P83 PF05262.6 EMR63821.1 - 3.4 5.8 13.9 4 5.5 9.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Vfa1 PF08432.5 EMR63821.1 - 4 7.4 18.3 6.3 6.7 12.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDRGK PF09756.4 EMR63821.1 - 6 6.2 24.1 8.3 5.7 16.7 1.1 1 0 0 1 1 1 0 DDRGK domain DUF2870 PF11069.3 EMR63821.1 - 6.9 6.7 12.8 0.71 9.9 4.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) V_ATPase_I PF01496.14 EMR63821.1 - 7.7 4.2 6.6 10 3.8 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MCPVI PF02993.9 EMR63821.1 - 7.7 6.5 10.9 10 6.2 7.5 1.3 1 0 0 1 1 1 0 Minor capsid protein VI POT1 PF02765.12 EMR63822.1 - 6.1e-08 32.6 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 adh_short PF00106.20 EMR63823.1 - 5.5e-22 78.4 0.1 1.1e-21 77.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR63823.1 - 6e-06 26.2 0.1 1.3e-05 25.0 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR63823.1 - 0.00011 21.9 1.5 0.0019 17.9 1.0 2.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR63823.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding VWA_2 PF13519.1 EMR63824.1 - 0.053 13.6 0.0 0.11 12.5 0.0 1.4 1 1 0 1 1 1 0 von Willebrand factor type A domain Yip1 PF04893.12 EMR63825.1 - 0.089 12.2 5.1 0.18 11.2 3.5 1.5 1 1 0 1 1 1 0 Yip1 domain PTR2 PF00854.16 EMR63826.1 - 1.7e-24 86.3 8.9 1.9e-13 49.9 0.7 2.1 2 0 0 2 2 2 2 POT family IncA PF04156.9 EMR63826.1 - 9.4 5.7 7.6 20 4.6 5.3 1.5 1 0 0 1 1 1 0 IncA protein GFO_IDH_MocA PF01408.17 EMR63827.1 - 8.7e-12 45.6 1.3 4.2e-11 43.4 0.9 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.1 EMR63827.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain NAD_binding_3 PF03447.11 EMR63827.1 - 0.1 12.9 0.2 0.2 12.0 0.1 1.6 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Rox3 PF08633.5 EMR63828.1 - 2.2e-46 158.5 0.3 3.2e-46 158.0 0.2 1.2 1 0 0 1 1 1 1 Rox3 mediator complex subunit UQ_con PF00179.21 EMR63829.1 - 7.8e-37 125.8 0.0 9.9e-37 125.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMR63829.1 - 0.065 12.9 0.0 0.22 11.2 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 EMR63829.1 - 0.28 11.0 1.0 0.84 9.5 0.7 1.8 1 1 0 1 1 1 0 RWD domain EBP PF05241.7 EMR63830.1 - 3.8e-72 241.4 3.9 4.4e-72 241.1 2.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein Cauli_VI PF01693.11 EMR63831.1 - 4.4e-23 81.0 4.9 1.3e-12 47.5 0.2 2.7 3 0 0 3 3 3 2 Caulimovirus viroplasmin MARVEL PF01284.18 EMR63832.1 - 2.6e-08 33.7 7.6 3.8e-08 33.2 5.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.1 EMR63832.1 - 0.095 12.8 2.1 0.16 12.0 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) CbiM PF01891.11 EMR63832.1 - 0.14 11.7 3.0 0.18 11.3 2.1 1.1 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region zf-RING_2 PF13639.1 EMR63833.1 - 4e-12 45.7 5.6 8.6e-12 44.7 3.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMR63833.1 - 4.9e-08 32.9 2.0 1.4e-07 31.4 1.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMR63833.1 - 2.1e-07 30.8 5.9 2.1e-07 30.8 4.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMR63833.1 - 6.7e-07 28.8 5.4 6.7e-07 28.8 3.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMR63833.1 - 1.7e-05 24.4 4.0 1.7e-05 24.4 2.7 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR63833.1 - 0.00013 21.6 4.1 0.00013 21.6 2.8 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EMR63833.1 - 0.00019 21.1 2.4 0.00048 19.9 1.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EMR63833.1 - 0.00022 21.2 4.0 0.00043 20.2 2.8 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.1 EMR63833.1 - 0.0094 15.6 0.9 0.0094 15.6 0.6 2.4 1 1 1 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.3 EMR63833.1 - 0.024 14.5 6.5 0.039 13.9 3.5 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EMR63833.1 - 0.025 14.4 4.3 0.097 12.5 3.0 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 EMR63833.1 - 0.13 12.3 0.9 0.27 11.2 0.6 1.5 1 0 0 1 1 1 0 RING-like domain DHDPS PF00701.17 EMR63835.1 - 3.9e-34 117.5 0.0 4.5e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family SMC_N PF02463.14 EMR63836.1 - 4.3e-51 173.2 29.9 1.7e-50 171.3 20.7 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EMR63836.1 - 3e-24 85.2 0.0 2.6e-23 82.2 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain Reo_sigmaC PF04582.7 EMR63836.1 - 2.1e-10 40.3 23.4 5.5e-07 29.0 0.6 5.2 4 1 2 6 6 6 2 Reovirus sigma C capsid protein AAA_29 PF13555.1 EMR63836.1 - 2.7e-08 33.2 0.0 6.3e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EMR63836.1 - 1.3e-06 28.6 22.8 0.00011 22.3 0.2 4.1 3 2 0 3 3 3 2 AAA domain DUF3584 PF12128.3 EMR63836.1 - 8e-06 23.5 109.9 0.0015 16.0 13.9 4.3 4 0 0 4 4 4 4 Protein of unknown function (DUF3584) Spc7 PF08317.6 EMR63836.1 - 0.00064 18.4 19.5 0.00064 18.4 13.5 7.1 3 2 4 7 7 7 3 Spc7 kinetochore protein SbcCD_C PF13558.1 EMR63836.1 - 0.0023 17.7 0.0 0.013 15.4 0.0 2.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ADIP PF11559.3 EMR63836.1 - 0.0071 16.2 4.7 0.0071 16.2 3.3 8.3 4 2 2 7 7 6 3 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 EMR63836.1 - 0.047 13.5 116.8 0.011 15.6 13.8 6.7 5 2 0 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 EMR63836.1 - 0.11 10.9 114.5 0.092 11.1 0.1 6.2 4 2 2 6 6 6 0 AAA domain WEMBL PF05701.6 EMR63836.1 - 0.35 9.2 116.5 0.68 8.3 5.2 5.3 4 1 0 4 4 4 0 Weak chloroplast movement under blue light AAA_22 PF13401.1 EMR63836.1 - 2.3 8.3 7.6 9.9 6.3 0.0 4.6 4 1 0 5 5 4 0 AAA domain DASH_Dam1 PF08653.5 EMR63836.1 - 4.9 7.0 5.7 22 4.9 0.1 3.8 3 1 0 3 3 3 0 DASH complex subunit Dam1 UBA_4 PF14555.1 EMR63837.1 - 6.3e-08 32.0 0.1 1.2e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Takusan PF04822.8 EMR63837.1 - 1.9 8.3 5.6 0.74 9.6 1.5 2.0 2 0 0 2 2 2 0 Takusan DnaJ PF00226.26 EMR63838.1 - 2.9e-26 90.9 4.1 4.4e-26 90.3 2.8 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EMR63838.1 - 4.9e-23 80.8 2.4 1.1e-19 70.1 0.1 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DUF2823 PF11034.3 EMR63839.1 - 4.9e-27 93.8 17.1 5.5e-27 93.6 11.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) DUF3756 PF12581.3 EMR63839.1 - 0.15 11.7 0.3 2.4 7.9 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3756) BTB PF00651.26 EMR63842.1 - 2.1e-16 59.8 0.0 2.4e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Fungal_trans_2 PF11951.3 EMR63843.1 - 2.6e-50 171.1 1.0 4.1e-50 170.4 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nop16 PF09420.5 EMR63844.1 - 7.9e-50 169.1 6.7 1.2e-49 168.6 4.6 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Prothymosin PF03247.9 EMR63844.1 - 0.0056 16.8 18.7 0.0056 16.8 12.9 2.1 1 1 1 2 2 2 1 Prothymosin/parathymosin family CDC45 PF02724.9 EMR63844.1 - 0.017 13.2 9.3 0.022 12.7 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EMR63844.1 - 0.035 12.0 7.5 0.038 11.9 5.2 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EMR63844.1 - 0.042 12.9 10.2 0.058 12.4 7.1 1.3 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.7 EMR63844.1 - 1.4 8.0 5.4 1.8 7.7 3.7 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2838 PF10998.3 EMR63845.1 - 6.5e-45 151.5 11.8 6.5e-45 151.5 8.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) Apolipoprotein PF01442.13 EMR63845.1 - 0.0038 16.7 4.0 0.0069 15.9 2.2 1.7 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Mnd1 PF03962.10 EMR63845.1 - 0.018 14.7 0.4 0.018 14.7 0.3 1.6 2 0 0 2 2 2 0 Mnd1 family Fzo_mitofusin PF04799.8 EMR63845.1 - 0.059 12.7 0.3 0.16 11.3 0.2 1.7 1 1 0 1 1 1 0 fzo-like conserved region Atg14 PF10186.4 EMR63845.1 - 0.36 9.7 4.5 0.62 8.9 3.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2458 PF10454.4 EMR63845.1 - 0.51 10.2 3.8 0.64 9.8 1.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) DUF3584 PF12128.3 EMR63845.1 - 0.75 7.0 5.4 1 6.5 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF349 PF03993.7 EMR63845.1 - 0.9 9.7 7.0 1.9 8.7 4.9 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) MFS_1 PF07690.11 EMR63846.1 - 2.6e-38 131.6 43.4 5.1e-38 130.6 30.1 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR63846.1 - 3.7e-14 52.1 11.9 3.7e-14 52.1 8.2 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EMR63846.1 - 0.0056 14.9 12.4 0.0081 14.3 7.6 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FUSC_2 PF13515.1 EMR63847.1 - 0.33 10.8 6.3 0.46 10.3 4.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein-like APH PF01636.18 EMR63849.1 - 2.7e-08 33.8 6.0 4.4e-08 33.1 4.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMR63849.1 - 0.0022 17.6 0.3 0.018 14.6 0.1 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase Glyco_hydro_71 PF03659.9 EMR63850.1 - 3.6e-161 535.9 4.6 4.7e-161 535.5 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF2406 PF10295.4 EMR63851.1 - 6.1e-20 71.5 0.2 6.1e-20 71.5 0.1 2.7 2 1 0 2 2 2 1 Uncharacterised protein (DUF2406) Ribosomal_L35Ae PF01247.13 EMR63852.1 - 2.8e-42 142.4 0.7 3.1e-42 142.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EMR63852.1 - 5.4e-05 23.0 0.1 0.029 14.3 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Sugar_tr PF00083.19 EMR63853.1 - 3.5e-80 269.7 24.2 4.4e-80 269.4 16.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR63853.1 - 1.7e-24 86.2 32.3 8.8e-24 83.8 22.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR63853.1 - 1.1e-06 27.2 3.4 1.7e-06 26.5 2.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ABC_membrane PF00664.18 EMR63854.1 - 3.6e-83 279.1 36.1 8.1e-50 169.7 13.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMR63854.1 - 3.1e-63 212.1 0.0 1.3e-29 103.2 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMR63854.1 - 1.1e-14 54.1 3.7 1.5e-06 27.6 2.5 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMR63854.1 - 3.9e-13 50.0 0.2 9.4e-05 22.5 0.2 3.4 2 1 0 3 3 3 3 AAA domain ABC_ATPase PF09818.4 EMR63854.1 - 1.2e-09 37.3 0.0 0.005 15.4 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EMR63854.1 - 5e-09 36.4 0.8 0.0019 18.2 0.2 4.0 3 1 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EMR63854.1 - 4.7e-08 32.3 0.0 0.0019 17.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMR63854.1 - 7.6e-08 33.2 0.9 0.0081 16.9 0.5 2.8 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMR63854.1 - 1.3e-07 31.8 0.5 0.03 14.4 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EMR63854.1 - 2.4e-07 30.1 0.7 0.0004 19.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF3987 PF13148.1 EMR63854.1 - 6.2e-06 25.0 1.0 2.6e-05 22.9 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_15 PF13175.1 EMR63854.1 - 3e-05 23.2 3.1 0.015 14.4 2.1 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.24 EMR63854.1 - 0.00011 22.4 0.7 8.9 6.5 0.0 4.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EMR63854.1 - 0.00014 21.7 1.1 0.52 10.2 0.1 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EMR63854.1 - 0.00017 21.8 0.4 0.24 11.7 0.3 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMR63854.1 - 0.00018 21.0 0.4 0.77 9.1 0.0 3.2 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.1 EMR63854.1 - 0.00025 20.7 0.3 0.029 14.1 0.0 3.2 3 0 0 3 3 2 1 Part of AAA domain AAA_14 PF13173.1 EMR63854.1 - 0.00083 19.2 0.5 0.23 11.3 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EMR63854.1 - 0.00092 18.9 0.1 1.7 8.4 0.0 3.3 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EMR63854.1 - 0.0011 18.4 0.0 0.029 13.7 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain AAA_30 PF13604.1 EMR63854.1 - 0.0013 18.3 6.4 0.52 9.8 0.1 4.2 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.1 EMR63854.1 - 0.0017 18.2 0.2 0.14 12.0 0.0 3.0 4 0 0 4 4 2 1 AAA domain ATP-synt_ab PF00006.20 EMR63854.1 - 0.0021 17.6 0.2 0.41 10.1 0.0 2.8 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.13 EMR63854.1 - 0.0034 16.9 0.0 2 7.9 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 EMR63854.1 - 0.0057 15.7 0.0 6.4 5.8 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_23 PF13476.1 EMR63854.1 - 0.0061 16.9 11.9 0.67 10.2 6.4 3.0 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.10 EMR63854.1 - 0.0065 15.2 0.0 0.29 9.7 0.1 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 EMR63854.1 - 0.014 15.3 0.2 2.6 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EMR63854.1 - 0.03 13.1 0.1 1.4 7.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_11 PF13086.1 EMR63854.1 - 0.033 13.7 0.2 0.15 11.5 0.2 1.9 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 EMR63854.1 - 0.033 14.6 0.8 14 6.1 0.2 2.9 2 0 0 2 2 2 0 Miro-like protein VMA21 PF09446.5 EMR63855.1 - 3.6e-16 58.8 7.7 5e-16 58.3 5.3 1.2 1 0 0 1 1 1 1 VMA21-like domain Peptidase_C48 PF02902.14 EMR63856.1 - 1.6e-15 57.2 0.1 4.1e-15 55.9 0.1 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SAICAR_synt PF01259.13 EMR63857.1 - 1.6e-40 138.7 0.0 1.9e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase G6PD_C PF02781.11 EMR63858.1 - 1.7e-134 447.2 0.0 2.3e-134 446.8 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EMR63858.1 - 1.8e-63 214.1 0.0 3e-63 213.3 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain AMP-binding PF00501.23 EMR63860.1 - 5.7e-24 84.2 0.1 9.1e-24 83.6 0.1 1.3 1 1 0 1 1 1 1 AMP-binding enzyme Tet_JBP PF12851.2 EMR63861.1 - 8.4e-06 25.1 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Sugar_tr PF00083.19 EMR63862.1 - 5.6e-72 242.7 20.8 6.3e-72 242.5 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR63862.1 - 1.9e-25 89.3 28.9 3.2e-25 88.5 19.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR63862.1 - 5e-05 21.7 1.9 5e-05 21.7 1.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PUCC PF03209.10 EMR63862.1 - 0.31 9.7 17.3 0.011 14.4 4.4 3.1 2 2 1 3 3 3 0 PUCC protein DUF3437 PF11919.3 EMR63864.1 - 2.1e-31 107.4 0.0 5.5e-31 106.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EMR63864.1 - 0.0054 16.6 0.2 20 5.6 0.1 4.8 4 0 0 4 4 4 1 HEAT repeat RPAP3_C PF13877.1 EMR63864.1 - 0.01 15.7 0.1 0.04 13.8 0.0 2.1 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 PWI PF01480.12 EMR63865.1 - 0.054 13.6 0.6 2.1 8.5 0.0 3.2 3 1 0 3 3 3 0 PWI domain GST_C_3 PF14497.1 EMR63867.1 - 4.7e-09 36.6 0.0 6.7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMR63867.1 - 0.00052 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain adh_short PF00106.20 EMR63868.1 - 6.4e-07 29.4 0.0 1.8e-06 27.9 0.0 1.7 1 1 1 2 2 2 1 short chain dehydrogenase adh_short PF00106.20 EMR63869.1 - 2e-16 60.3 0.0 3e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR63869.1 - 6.5e-07 29.1 0.0 8.6e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR63869.1 - 0.0011 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TPR_11 PF13414.1 EMR63870.1 - 0.0055 16.3 0.9 4.9 6.8 0.1 3.2 3 0 0 3 3 3 2 TPR repeat Fungal_trans_2 PF11951.3 EMR63870.1 - 0.13 10.8 6.2 5.1 5.5 3.0 2.9 2 1 0 2 2 2 0 Fungal specific transcription factor domain Fungal_trans PF04082.13 EMR63871.1 - 5.9e-18 64.6 1.0 9.2e-18 64.0 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TT_ORF2a PF08197.6 EMR63872.1 - 0.079 12.7 0.1 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 pORF2a truncated protein DUF202 PF02656.10 EMR63872.1 - 0.095 12.9 2.1 3.5 7.9 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) PRA1 PF03208.14 EMR63872.1 - 0.62 9.3 3.1 1 8.6 2.1 1.5 1 1 0 1 1 1 0 PRA1 family protein MFS_1 PF07690.11 EMR63873.1 - 4.9e-24 84.7 50.0 1.6e-16 59.9 13.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3318 PF11780.3 EMR63873.1 - 1.3 8.5 4.0 1.4 8.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3318) Urotensin_II PF02083.10 EMR63873.1 - 4.9 6.6 5.6 19 4.8 0.7 2.5 2 0 0 2 2 2 0 Urotensin II LUC7 PF03194.10 EMR63874.1 - 6.6e-65 219.1 0.0 8.3e-65 218.8 0.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DASH_Duo1 PF08651.5 EMR63874.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Duo1 zf-DHHC PF01529.15 EMR63876.1 - 9.5e-08 31.6 4.3 9.5e-08 31.6 3.0 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase Pkinase PF00069.20 EMR63877.1 - 0.00065 18.9 0.0 0.4 9.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Ribonuc_L-PSP PF01042.16 EMR63878.1 - 3.3e-19 68.8 0.0 4.9e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP NOGCT PF08155.6 EMR63878.1 - 0.11 12.2 0.1 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 NOGCT (NUC087) domain Sec7_N PF12783.2 EMR63879.1 - 9.8e-37 125.9 0.2 2.2e-35 121.5 0.0 2.3 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Gpi16 PF04113.9 EMR63880.1 - 2.7e-229 761.9 0.0 3.3e-229 761.5 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component RRM_1 PF00076.17 EMR63881.1 - 0.0081 15.7 0.0 0.31 10.6 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAF-1_p150 PF11600.3 EMR63883.1 - 0.055 12.8 12.8 0.1 11.9 8.8 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1682 PF07946.9 EMR63883.1 - 1.6 7.5 6.5 2 7.1 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF1479 PF07350.7 EMR63884.1 - 2.7e-115 385.2 0.0 3.3e-115 384.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 EMR63884.1 - 0.041 13.9 0.1 3.4 7.6 0.2 2.9 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) p450 PF00067.17 EMR63886.1 - 1.2e-54 185.6 0.0 2e-54 184.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 EMR63886.1 - 5.9e-18 65.5 0.3 3.5e-17 62.9 0.2 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR63886.1 - 1.4e-13 51.0 4.1 6.7e-13 48.8 2.9 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR63886.1 - 0.00042 20.0 1.8 0.0026 17.4 0.1 2.3 2 0 0 2 2 2 1 KR domain AAA PF00004.24 EMR63887.1 - 1.9e-25 89.5 0.0 3.5e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMR63887.1 - 1.1e-06 27.8 0.0 1.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EMR63887.1 - 1.2e-05 26.1 0.0 3.6e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMR63887.1 - 6.1e-05 23.1 0.0 0.00021 21.4 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 EMR63887.1 - 0.00032 20.7 0.2 0.0018 18.3 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EMR63887.1 - 0.00071 19.8 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMR63887.1 - 0.0011 18.6 0.0 0.0063 16.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EMR63887.1 - 0.0019 17.7 1.3 0.031 13.8 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EMR63887.1 - 0.0022 17.4 0.1 0.0093 15.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain BCS1_N PF08740.6 EMR63887.1 - 0.0048 16.5 0.0 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA_33 PF13671.1 EMR63887.1 - 0.0064 16.3 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMR63887.1 - 0.007 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EMR63887.1 - 0.0079 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EMR63887.1 - 0.013 15.4 0.0 0.052 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EMR63887.1 - 0.032 13.1 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 EMR63887.1 - 0.035 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain TIP49 PF06068.8 EMR63887.1 - 0.06 12.0 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_11 PF13086.1 EMR63887.1 - 0.13 11.8 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain Tyrosinase PF00264.15 EMR63889.1 - 7.3e-18 65.5 0.1 1.3e-17 64.7 0.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase PE_PPE_C PF12484.3 EMR63889.1 - 1.3 9.9 5.9 5.3 8.0 4.1 1.9 1 1 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal HSP70 PF00012.15 EMR63890.1 - 3.5e-05 21.9 0.0 4.9e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein DUF1693 PF07984.7 EMR63890.1 - 0.024 13.8 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1693) Cellulase PF00150.13 EMR63891.1 - 6.2e-23 81.3 1.2 1.2e-22 80.4 0.3 1.9 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) FlxA PF14282.1 EMR63891.1 - 0.033 14.1 48.7 0.3 11.0 4.1 6.8 2 2 3 6 6 6 0 FlxA-like protein DUF3439 PF11921.3 EMR63891.1 - 8.1 6.2 6.9 1.7 8.3 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) TRAUB PF08164.7 EMR63892.1 - 8.1e-30 102.7 0.0 8.1e-30 102.7 0.0 2.9 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EMR63892.1 - 1.2e-26 93.4 5.9 1.2e-26 93.4 4.1 2.7 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor Glyco_hydro_16 PF00722.16 EMR63893.1 - 2.8e-18 65.8 0.1 1.1e-17 63.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EMR63893.1 - 2.4e-05 22.7 0.9 0.0016 16.7 0.2 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Sulfatase PF00884.18 EMR63894.1 - 5.1e-77 259.0 0.0 6.4e-77 258.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 EMR63894.1 - 0.015 15.5 0.1 0.3 11.3 0.1 2.5 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Glyco_hydro_72 PF03198.9 EMR63895.1 - 8.9e-115 382.9 3.8 1.2e-114 382.5 2.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EMR63895.1 - 4e-21 75.2 6.7 4e-21 75.2 4.6 1.8 2 0 0 2 2 2 1 X8 domain DUF4537 PF15057.1 EMR63896.1 - 0.017 14.8 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Rad9_Rad53_bind PF08605.5 EMR63896.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding ParA PF10609.4 EMR63897.1 - 5.1e-28 96.7 0.4 9.6e-28 95.8 0.3 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EMR63897.1 - 3.8e-12 46.0 0.0 6.2e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EMR63897.1 - 2.6e-08 33.9 0.0 1.8e-07 31.2 0.0 2.0 1 1 1 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EMR63897.1 - 3.2e-05 23.2 0.1 0.12 11.5 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.6 EMR63897.1 - 0.00045 19.3 0.1 0.0011 18.0 0.0 1.6 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 EMR63897.1 - 0.00083 18.4 0.3 0.026 13.5 0.1 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EMR63897.1 - 0.0081 15.5 0.3 0.016 14.5 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.1 EMR63897.1 - 0.01 15.4 0.6 0.43 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain YhjQ PF06564.7 EMR63897.1 - 0.037 13.3 0.4 0.11 11.8 0.1 1.8 2 0 0 2 2 2 0 YhjQ protein AAA_19 PF13245.1 EMR63897.1 - 0.085 12.6 0.5 6.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain DUF533 PF04391.7 EMR63898.1 - 0.15 11.3 0.6 0.19 11.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DUF2235 PF09994.4 EMR63901.1 - 1.1e-103 346.4 1.4 1.5e-103 346.0 0.9 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Fungal_trans_2 PF11951.3 EMR63902.1 - 8.6e-06 24.5 0.3 1.1e-05 24.2 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 EMR63904.1 - 1.2e-18 67.2 0.0 1.9e-18 66.5 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR63904.1 - 6.5e-08 32.7 0.3 1.8e-07 31.3 0.1 1.9 2 1 0 2 2 2 1 NADH(P)-binding HET PF06985.6 EMR63905.1 - 2.2e-22 79.7 0.0 3.7e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3632 PF12311.3 EMR63906.1 - 1.7e-08 34.4 0.2 2.4e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Alginate_lyase PF05426.7 EMR63907.1 - 2.5e-08 33.6 3.7 7.4e-08 32.0 2.6 1.7 1 1 0 1 1 1 1 Alginate lyase DUF3612 PF12268.3 EMR63907.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) Abhydrolase_5 PF12695.2 EMR63909.1 - 1.9e-08 34.1 0.0 2.4e-08 33.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR63909.1 - 3.2e-06 27.1 0.1 4.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMR63909.1 - 0.0002 20.7 0.0 0.00028 20.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 EMR63909.1 - 0.22 11.2 1.1 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4551 PF15087.1 EMR63910.1 - 0.029 12.7 0.7 0.042 12.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) HET PF06985.6 EMR63911.1 - 2e-14 53.9 0.0 5.7e-10 39.4 0.0 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) BAF1_ABF1 PF04684.8 EMR63911.1 - 0.64 8.7 3.6 1.6 7.5 2.5 1.6 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FAD_binding_4 PF01565.18 EMR63912.1 - 7.8e-15 54.5 0.0 1.2e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_6 PF08030.7 EMR63913.1 - 1e-31 109.9 0.0 2.4e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMR63913.1 - 4.1e-21 74.8 0.0 1.2e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EMR63913.1 - 4.8e-16 58.9 9.1 4.8e-16 58.9 6.3 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EMR63913.1 - 0.00044 20.3 0.0 0.00094 19.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Abhydrolase_6 PF12697.2 EMR63914.1 - 1.1e-06 28.7 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family COX6B PF02297.12 EMR63917.1 - 8e-21 73.8 4.6 1.1e-20 73.4 3.2 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.6 EMR63917.1 - 0.0019 18.2 0.2 0.0028 17.7 0.1 1.3 1 0 0 1 1 1 1 Prolamin-like SYS1 PF09801.4 EMR63918.1 - 1.2e-49 168.0 4.9 1.4e-49 167.8 3.4 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Kinocilin PF15033.1 EMR63918.1 - 0.023 14.2 0.7 0.055 12.9 0.1 1.8 1 1 1 2 2 2 0 Kinocilin protein Tet_JBP PF12851.2 EMR63919.1 - 2.9e-06 26.6 0.0 5.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily AAA PF00004.24 EMR63920.1 - 4.4e-19 68.9 0.0 8e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR63920.1 - 3e-05 24.1 0.1 0.00028 21.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EMR63920.1 - 0.00013 22.7 0.0 0.00028 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR63920.1 - 0.0002 21.4 0.1 0.00057 19.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EMR63920.1 - 0.00083 19.1 0.0 0.0014 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EMR63920.1 - 0.0022 17.9 0.0 0.0071 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EMR63920.1 - 0.013 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.17 EMR63920.1 - 0.027 13.9 0.1 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EMR63920.1 - 0.028 14.2 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMR63920.1 - 0.039 14.2 0.1 0.09 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMR63920.1 - 0.044 13.5 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 EMR63920.1 - 0.055 12.4 0.0 0.087 11.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Torsin PF06309.6 EMR63920.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_3 PF07726.6 EMR63920.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.7 EMR63920.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zot PF05707.7 EMR63920.1 - 0.12 11.8 0.1 3.9 6.8 0.0 2.4 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) Zeta_toxin PF06414.7 EMR63920.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 EMR63920.1 - 0.16 11.9 0.3 6 6.8 0.1 2.4 1 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EMR63920.1 - 0.17 11.5 0.4 1.8 8.1 0.0 2.5 2 1 1 3 3 3 0 NACHT domain HET PF06985.6 EMR63921.1 - 1.8e-24 86.4 0.0 3.8e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_tran_28_C PF04101.11 EMR63921.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF563 PF04577.9 EMR63922.1 - 6.7e-26 91.4 0.1 1.1e-25 90.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF563) IPK PF03770.11 EMR63922.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 Inositol polyphosphate kinase p450 PF00067.17 EMR63923.1 - 3.8e-32 111.4 0.0 4.6e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pec_lyase_C PF00544.14 EMR63924.1 - 3.4e-30 105.0 3.0 5e-30 104.4 1.9 1.4 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EMR63924.1 - 1.2e-08 34.8 12.2 0.00022 20.9 5.1 2.4 1 1 1 2 2 2 2 Right handed beta helix region Helicase_C PF00271.26 EMR63925.1 - 2.3e-11 43.3 0.0 5.7e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ligase_CoA PF00549.14 EMR63925.1 - 0.057 13.0 0.2 0.5 9.9 0.1 2.1 1 1 0 1 1 1 0 CoA-ligase Choline_transpo PF04515.7 EMR63928.1 - 2.2e-101 338.9 17.5 2.2e-101 338.9 12.2 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter UQ_con PF00179.21 EMR63929.1 - 2.7e-51 172.6 0.0 3.1e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMR63929.1 - 6.5e-05 22.6 0.0 7.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMR63929.1 - 0.0052 16.6 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EMR63929.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain adh_short PF00106.20 EMR63931.1 - 2.5e-10 40.5 0.1 3.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR63931.1 - 0.0037 17.0 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EMR63931.1 - 0.068 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RdRP PF05183.7 EMR63932.1 - 2e-66 224.9 0.0 3.3e-66 224.2 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase PIP5K PF01504.13 EMR63933.1 - 5e-71 238.7 0.1 9.9e-71 237.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PUF PF00806.14 EMR63934.1 - 2.5e-14 51.8 0.0 0.058 12.9 0.0 6.6 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat Met_synt_B12 PF02965.12 EMR63934.1 - 0.061 12.5 0.0 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain Acyl-CoA_dh_N PF02771.11 EMR63935.1 - 2.1e-23 83.0 0.1 4.2e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EMR63935.1 - 3e-21 76.1 0.5 5.4e-21 75.2 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMR63935.1 - 4.1e-17 61.4 0.0 1e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMR63935.1 - 6.5e-07 29.6 0.4 1.1e-06 28.9 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RraB PF06877.6 EMR63937.1 - 0.12 13.0 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 Regulator of ribonuclease activity B NAD_binding_4 PF07993.7 EMR63938.1 - 3.8e-34 117.7 0.0 5.7e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EMR63938.1 - 1.5e-14 54.0 0.0 2.8e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMR63938.1 - 1.9e-06 28.0 0.0 5.9e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 EMR63938.1 - 0.00022 21.1 0.2 0.011 15.6 0.0 2.6 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EMR63938.1 - 0.00058 18.8 0.1 0.16 10.8 0.0 2.5 2 1 0 2 2 2 2 RmlD substrate binding domain KR PF08659.5 EMR63938.1 - 0.00071 19.2 0.7 0.37 10.4 0.0 3.0 3 0 0 3 3 3 2 KR domain Polysacc_synt_2 PF02719.10 EMR63938.1 - 0.047 12.5 0.0 0.095 11.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RE_Alw26IDE PF09665.5 EMR63938.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) Dynamin_N PF00350.18 EMR63939.1 - 1.4e-27 96.5 0.0 2.5e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EMR63939.1 - 2.6e-16 59.2 0.0 4.5e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EMR63939.1 - 0.0032 17.3 0.0 0.018 14.9 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMR63939.1 - 0.005 17.3 0.0 0.018 15.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Glyco_hydro_43 PF04616.9 EMR63940.1 - 2.3e-13 49.8 1.3 8.7e-11 41.4 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Lipoxygenase PF00305.14 EMR63943.1 - 1.5e-25 89.2 0.0 2.6e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Lipoxygenase Peptidase_S8 PF00082.17 EMR63944.1 - 9.1e-31 107.0 12.3 4.9e-30 104.6 8.5 1.9 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMR63944.1 - 3.2e-11 43.6 0.2 2e-10 41.0 0.2 2.1 1 1 0 1 1 1 1 Peptidase inhibitor I9 Asp PF00026.18 EMR63945.1 - 7.6e-05 22.1 0.1 0.00028 20.2 0.1 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease EGF_2 PF07974.8 EMR63946.1 - 0.002 18.2 10.4 0.0035 17.4 7.2 1.4 1 0 0 1 1 1 1 EGF-like domain Glyco_hydro_43 PF04616.9 EMR63946.1 - 0.0033 16.5 4.9 0.13 11.3 0.1 3.1 1 1 2 3 3 3 2 Glycosyl hydrolases family 43 hEGF PF12661.2 EMR63946.1 - 0.051 13.6 1.0 0.14 12.2 0.7 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF EB PF01683.13 EMR63946.1 - 0.18 11.8 4.3 0.32 11.1 3.0 1.3 1 0 0 1 1 1 0 EB module Squash PF00299.13 EMR63946.1 - 3.8 7.4 7.3 10 6.0 5.1 1.7 1 1 0 1 1 1 0 Squash family serine protease inhibitor Lactonase PF10282.4 EMR63947.1 - 1.9e-39 135.7 0.0 2.4e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Amidase PF01425.16 EMR63948.1 - 1.6e-48 165.6 0.2 1.9e-45 155.5 0.2 2.1 2 0 0 2 2 2 2 Amidase YadA_stalk PF05662.9 EMR63948.1 - 0.22 11.3 2.0 0.27 11.0 0.1 2.2 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin XFP_N PF09364.5 EMR63949.1 - 1.5e-147 491.1 0.0 1.9e-147 490.7 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EMR63949.1 - 4.6e-82 273.9 0.0 1.3e-81 272.4 0.0 1.8 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EMR63949.1 - 1.1e-62 211.0 0.1 5.7e-62 208.7 0.0 2.0 1 1 1 2 2 2 1 XFP C-terminal domain Virulence_fact PF13769.1 EMR63949.1 - 0.11 12.3 0.1 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 Virulence factor PRANC PF09372.5 EMR63950.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 PRANC domain DUF1348 PF07080.6 EMR63951.1 - 3.1e-58 195.6 7.9 3.8e-58 195.3 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 EMR63951.1 - 4.7e-08 33.3 3.6 6.8e-08 32.8 2.5 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EMR63951.1 - 8.5e-06 25.9 0.7 1.3e-05 25.3 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 EMR63951.1 - 0.021 14.4 0.1 0.036 13.6 0.1 1.5 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Ribosomal_L24e PF01246.15 EMR63952.1 - 1.4e-20 72.9 0.4 1.4e-20 72.9 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e CMS1 PF14617.1 EMR63953.1 - 8e-55 185.6 0.1 1.3e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EMR63953.1 - 1.9e-05 24.2 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Chorion_2 PF03964.10 EMR63953.1 - 0.031 14.7 6.4 0.072 13.6 4.4 1.6 1 0 0 1 1 1 0 Chorion family 2 NapE PF06796.6 EMR63953.1 - 3 7.2 4.9 6.3 6.1 3.4 1.5 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE GSu_C4xC__C2xCH PF09698.5 EMR63953.1 - 6.7 6.9 6.0 0.92 9.7 1.0 2.0 2 0 0 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Redoxin PF08534.5 EMR63954.1 - 7.7e-36 122.8 0.1 8.6e-36 122.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EMR63954.1 - 1.2e-10 41.1 0.0 1.6e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family RGS PF00615.14 EMR63955.1 - 1.1e-05 25.4 0.2 0.0013 18.8 0.0 2.5 2 1 0 2 2 2 2 Regulator of G protein signaling domain Dak1 PF02733.12 EMR63956.1 - 1.1e-104 349.5 0.0 1.4e-104 349.1 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EMR63956.1 - 2e-37 128.5 2.5 3.8e-37 127.6 1.8 1.5 1 0 0 1 1 1 1 DAK2 domain F_bP_aldolase PF01116.15 EMR63957.1 - 3.1e-85 285.7 0.2 3.5e-85 285.5 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II NAD_binding_11 PF14833.1 EMR63958.1 - 8.7e-38 129.1 0.3 2.1e-24 85.8 0.0 2.3 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EMR63958.1 - 6.3e-33 113.9 0.1 1.7e-32 112.5 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMR63958.1 - 7.8e-05 23.0 0.0 0.001 19.4 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EMR63958.1 - 0.00075 19.1 0.1 0.0014 18.2 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EMR63958.1 - 0.0009 18.7 0.0 0.0021 17.5 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EMR63958.1 - 0.0042 16.4 0.0 0.057 12.7 0.0 2.4 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2758 PF10957.3 EMR63959.1 - 0.031 14.0 2.2 0.059 13.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2758) ATG16 PF08614.6 EMR63959.1 - 0.094 12.5 2.4 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4200 PF13863.1 EMR63959.1 - 1.5 8.7 7.1 0.33 10.8 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) PepX_C PF08530.5 EMR63960.1 - 1.7e-25 90.2 0.7 2.2e-25 89.8 0.5 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 EMR63960.1 - 7e-08 32.2 0.2 0.007 15.8 0.0 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DNA_ligase_A_C PF04679.10 EMR63960.1 - 0.057 13.8 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region LacAB_rpiB PF02502.13 EMR63961.1 - 6e-40 136.1 0.2 6.8e-40 135.9 0.2 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase MIT PF04212.13 EMR63964.1 - 2.4e-14 52.9 0.9 5.7e-14 51.7 0.6 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain GAS PF13851.1 EMR63965.1 - 0.0028 16.8 63.5 0.034 13.3 15.2 4.9 1 1 3 4 4 4 2 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 EMR63965.1 - 1.5 8.5 63.5 0.54 10.0 6.1 5.7 1 1 5 6 6 6 0 TATA element modulatory factor 1 TATA binding DUF3562 PF12085.3 EMR63965.1 - 1.7 8.5 12.8 2.6 7.9 0.1 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3562) SCO1-SenC PF02630.9 EMR63965.1 - 1.8 8.1 6.5 2.6 7.6 0.2 2.9 3 1 0 3 3 3 0 SCO1/SenC Reo_sigmaC PF04582.7 EMR63965.1 - 6.8 5.7 15.4 1.7 7.7 1.1 2.6 1 1 1 3 3 3 0 Reovirus sigma C capsid protein APG6 PF04111.7 EMR63965.1 - 9 5.2 69.1 0.097 11.7 15.3 4.0 1 1 3 4 4 4 0 Autophagy protein Apg6 Lipase_GDSL PF00657.17 EMR63966.1 - 6e-05 22.9 0.0 7.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.11 EMR63967.1 - 1.1e-12 47.3 13.6 1.1e-12 47.3 9.4 3.1 2 1 1 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR63967.1 - 2.6e-09 35.8 15.6 3.9e-05 22.0 1.9 3.0 2 1 1 3 3 3 3 Fungal trichothecene efflux pump (TRI12) FAD_binding_3 PF01494.14 EMR63969.1 - 2e-64 217.8 0.0 2.7e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF1989 PF09347.5 EMR63969.1 - 3.1e-47 160.1 0.0 5.2e-46 156.1 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.16 EMR63969.1 - 4.5e-19 68.2 0.0 8.7e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DAO PF01266.19 EMR63969.1 - 3.9e-05 22.7 0.1 8e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR63969.1 - 8.4e-05 22.5 0.4 0.00032 20.6 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Phe_hydrox_dim PF07976.7 EMR63969.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 EMR63969.1 - 0.00016 20.8 0.0 0.00027 20.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 EMR63969.1 - 0.0014 17.3 0.0 0.0045 15.6 0.0 1.8 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.19 EMR63969.1 - 0.0042 15.9 0.0 0.0069 15.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMR63969.1 - 0.005 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR63969.1 - 0.0051 16.7 0.4 0.039 13.8 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR63969.1 - 0.0062 15.5 0.0 0.0089 14.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EMR63969.1 - 0.0071 14.8 0.0 0.011 14.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein DUF2334 PF10096.4 EMR63969.1 - 0.0085 15.5 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.4 EMR63969.1 - 0.24 9.4 0.0 0.36 8.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) Herpes_UL6 PF01763.11 EMR63970.1 - 0.0068 14.6 0.5 0.0068 14.6 0.4 2.2 1 1 1 2 2 2 1 Herpesvirus UL6 like ARGLU PF15346.1 EMR63970.1 - 2.2 8.0 37.2 4.6 7.0 21.1 3.2 2 1 0 2 2 2 0 Arginine and glutamate-rich 1 DUF4192 PF13830.1 EMR63970.1 - 2.6 7.6 6.0 4.8 6.7 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF4407 PF14362.1 EMR63970.1 - 5.7 5.7 22.2 0.26 10.2 11.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF445 PF04286.7 EMR63970.1 - 9.7 5.6 18.4 20 4.5 12.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Helicase_C PF00271.26 EMR63971.1 - 0.0018 18.1 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ATP-gua_PtransN PF02807.10 EMR63973.1 - 0.036 14.2 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 ATP:guanido phosphotransferase, N-terminal domain TIM PF00121.13 EMR63975.1 - 4.8e-49 166.6 0.0 7e-47 159.5 0.0 2.7 1 1 0 1 1 1 1 Triosephosphate isomerase B12-binding PF02310.14 EMR63976.1 - 0.03 14.1 0.1 0.044 13.6 0.1 1.4 1 1 0 1 1 1 0 B12 binding domain Glyco_hydro_61 PF03443.9 EMR63978.1 - 3.6e-11 43.3 0.0 6.4e-11 42.4 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 FAD_binding_3 PF01494.14 EMR63979.1 - 6e-56 190.0 0.0 8e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain RNA_ligase PF09414.5 EMR63980.1 - 2.8e-14 53.3 0.0 2.4e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 RNA ligase Ribosomal_60s PF00428.14 EMR63981.1 - 0.031 14.6 14.0 0.079 13.3 9.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein K_channel_TID PF07941.6 EMR63981.1 - 0.053 13.7 5.9 0.16 12.2 4.1 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain UQ_con PF00179.21 EMR63982.1 - 1.1e-26 92.9 0.1 1.4e-26 92.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MFS_1 PF07690.11 EMR63983.1 - 3.8e-18 65.3 23.4 1.5e-16 60.0 16.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Lectin_N PF03954.9 EMR63983.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain MFS_1_like PF12832.2 EMR63983.1 - 0.26 11.0 9.2 0.029 14.1 1.1 3.1 4 0 0 4 4 4 0 MFS_1 like family DctQ PF04290.7 EMR63984.1 - 0.012 15.3 2.4 0.012 15.3 1.7 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Herpes_US9 PF06072.6 EMR63984.1 - 0.27 11.0 2.5 2.5 7.9 0.0 3.0 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 DUF572 PF04502.8 EMR63985.1 - 3e-55 187.6 0.0 5.5e-55 186.8 0.0 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF572) RRM_6 PF14259.1 EMR63985.1 - 0.035 14.0 0.1 12 5.9 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Med3 PF11593.3 EMR63985.1 - 0.22 10.7 2.6 0.29 10.3 1.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ABC2_membrane PF01061.19 EMR63986.1 - 3.5e-98 326.9 66.4 4.3e-51 173.0 15.0 3.5 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EMR63986.1 - 8.3e-34 116.8 0.0 1.1e-16 61.3 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EMR63986.1 - 2e-33 114.1 19.7 6.6e-33 112.4 0.1 3.6 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EMR63986.1 - 2.8e-22 78.5 0.1 9.2e-22 76.9 0.0 2.0 1 1 1 2 2 2 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 EMR63986.1 - 1.7e-07 31.4 0.9 2.8e-06 27.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EMR63986.1 - 3e-07 30.0 0.0 0.00016 21.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMR63986.1 - 8.2e-07 28.9 0.1 0.0081 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 EMR63986.1 - 1.7e-05 24.3 1.0 0.0027 17.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EMR63986.1 - 2e-05 23.8 0.1 0.00058 19.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMR63986.1 - 4.3e-05 22.9 0.8 0.0016 17.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 EMR63986.1 - 0.00011 21.3 56.2 0.00019 20.5 11.4 4.0 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 EMR63986.1 - 0.00015 21.8 0.0 0.25 11.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMR63986.1 - 0.00038 20.6 0.1 0.3 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMR63986.1 - 0.0015 18.8 0.3 0.028 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EMR63986.1 - 0.0019 17.5 0.0 1.2 8.2 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EMR63986.1 - 0.0022 18.8 0.0 0.042 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMR63986.1 - 0.0027 17.3 0.3 0.42 10.2 0.1 2.5 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 EMR63986.1 - 0.005 16.4 0.5 1.7 8.3 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EMR63986.1 - 0.013 15.2 2.6 3.5 7.4 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 EMR63986.1 - 0.014 15.3 0.5 0.19 11.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EMR63986.1 - 0.018 14.6 0.8 0.6 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EMR63986.1 - 0.025 14.7 0.2 8 6.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EMR63986.1 - 0.028 14.7 0.2 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMR63986.1 - 0.042 13.4 0.5 0.84 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EMR63986.1 - 0.069 13.6 0.0 22 5.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein IstB_IS21 PF01695.12 EMR63986.1 - 0.099 12.0 0.1 8.4 5.7 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SE PF00437.15 EMR63986.1 - 0.11 11.3 0.3 3 6.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EMR63986.1 - 0.34 10.6 0.4 15 5.2 0.1 2.9 3 0 0 3 3 3 0 NTPase AAA_15 PF13175.1 EMR63986.1 - 1.1 8.2 0.0 2 7.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane_2 PF12679.2 EMR63986.1 - 3.6 6.3 22.6 2.2 7.0 4.3 2.6 2 0 0 2 2 2 0 ABC-2 family transporter protein Beta-lactamase PF00144.19 EMR63987.1 - 1.1e-32 113.3 0.0 2e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_7 PF00840.15 EMR63988.1 - 6.9e-147 489.3 12.6 8.3e-147 489.0 8.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Cyclase PF04199.8 EMR63989.1 - 1.9e-17 63.4 0.3 2.8e-17 62.9 0.2 1.3 1 0 0 1 1 1 1 Putative cyclase AvrB_AvrC PF05394.6 EMR63989.1 - 0.021 13.8 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Avirulence protein DOPA_dioxygen PF08883.6 EMR63990.1 - 3.4e-29 100.9 0.1 4.8e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family GFA PF04828.9 EMR63991.1 - 7.5e-23 80.2 0.0 1e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 EMR63991.1 - 0.018 14.7 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Aldedh PF00171.17 EMR63992.1 - 1.2e-147 491.9 0.0 1.4e-147 491.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.17 EMR63993.1 - 2.4e-41 141.7 0.0 2.9e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CK_II_beta PF01214.13 EMR63994.1 - 2.2e-77 258.7 0.0 1.3e-76 256.1 0.0 1.9 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EMR63994.1 - 0.0028 18.2 6.6 0.0028 18.2 4.6 2.4 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Nop25 PF09805.4 EMR63994.1 - 1.1 9.3 7.3 0.23 11.5 2.3 1.8 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) VID27 PF08553.5 EMR63994.1 - 1.6 6.8 4.6 2.4 6.2 3.2 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nucleoplasmin PF03066.10 EMR63994.1 - 2 7.9 12.2 1.2 8.6 5.3 2.1 2 0 0 2 2 2 0 Nucleoplasmin Myc_N PF01056.13 EMR63994.1 - 3.1 6.8 9.7 0.055 12.6 2.1 1.4 2 0 0 2 2 2 0 Myc amino-terminal region FAM176 PF14851.1 EMR63994.1 - 5.7 6.5 6.9 0.98 9.0 1.5 1.9 2 0 0 2 2 2 0 FAM176 family F-box-like PF12937.2 EMR63995.1 - 3.6e-06 26.5 0.1 6.2e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMR63995.1 - 0.0012 18.3 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain BUD22 PF09073.5 EMR63995.1 - 0.0036 16.4 0.2 0.0036 16.4 0.2 1.6 2 0 0 2 2 2 1 BUD22 Cnd2 PF05786.9 EMR63995.1 - 0.045 12.2 5.8 0.078 11.4 4.1 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 Glypican PF01153.14 EMR63995.1 - 0.5 8.9 0.9 0.64 8.5 0.7 1.1 1 0 0 1 1 1 0 Glypican HSP90 PF00183.13 EMR63995.1 - 0.89 7.8 7.9 1.6 7.0 5.5 1.3 1 0 0 1 1 1 0 Hsp90 protein ABC2_membrane PF01061.19 EMR63996.1 - 1.2e-79 266.3 57.1 5.4e-41 140.0 13.6 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EMR63996.1 - 1.6e-35 122.4 0.0 1.5e-16 60.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EMR63996.1 - 6.9e-28 96.3 3.3 3.1e-24 84.6 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EMR63996.1 - 1.5e-08 34.5 0.0 5.2e-08 32.8 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EMR63996.1 - 2.3e-07 30.4 0.6 0.0035 16.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EMR63996.1 - 4.4e-07 30.7 0.0 0.0035 18.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EMR63996.1 - 5.4e-06 26.3 0.0 0.0096 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EMR63996.1 - 2.5e-05 24.3 0.0 0.079 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMR63996.1 - 4.4e-05 23.6 0.0 0.089 12.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EMR63996.1 - 7e-05 22.2 0.2 0.0054 16.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EMR63996.1 - 0.00012 21.5 1.1 0.0062 16.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EMR63996.1 - 0.00025 21.0 0.1 0.027 14.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EMR63996.1 - 0.00053 19.6 0.4 0.56 9.9 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain DUF258 PF03193.11 EMR63996.1 - 0.00068 18.8 0.0 0.0063 15.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 EMR63996.1 - 0.001 18.2 45.0 0.002 17.2 15.0 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.1 EMR63996.1 - 0.0012 19.1 0.0 0.14 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EMR63996.1 - 0.0016 18.0 1.3 1.3 8.6 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EMR63996.1 - 0.0021 18.0 0.9 0.19 11.6 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EMR63996.1 - 0.0026 17.4 0.2 1.9 8.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 EMR63996.1 - 0.006 15.8 0.0 0.66 9.1 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 EMR63996.1 - 0.018 14.4 0.2 0.91 8.9 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 EMR63996.1 - 0.024 14.8 0.0 9.3 6.4 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EMR63996.1 - 0.038 13.4 0.2 2.6 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 EMR63996.1 - 0.046 13.4 0.0 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase DnaB_C PF03796.10 EMR63996.1 - 0.063 12.1 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ATP-synt_ab PF00006.20 EMR63996.1 - 0.067 12.6 0.0 0.8 9.1 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 EMR63996.1 - 0.071 12.6 0.3 3.3 7.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EMR63996.1 - 0.072 12.5 0.5 2.3 7.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mor PF08765.6 EMR63996.1 - 0.075 12.8 0.0 0.79 9.5 0.0 2.4 2 0 0 2 2 2 0 Mor transcription activator family AAA_23 PF13476.1 EMR63996.1 - 0.078 13.2 0.0 0.51 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EMR63996.1 - 0.082 13.4 0.0 6.1 7.3 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_15 PF13175.1 EMR63996.1 - 0.54 9.2 0.0 3.4 6.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Pyr_redox_3 PF13738.1 EMR63997.1 - 4.6e-15 56.2 0.0 6.9e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR63997.1 - 3.4e-14 51.9 0.0 1.7e-13 49.6 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMR63997.1 - 2.4e-12 46.4 0.0 4.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DUF4147 PF13660.1 EMR63997.1 - 0.06 12.4 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Pyr_redox PF00070.22 EMR63997.1 - 0.14 12.6 0.2 0.35 11.3 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amidoligase_2 PF12224.3 EMR63998.1 - 0.044 13.3 0.2 0.15 11.6 0.2 1.8 1 1 0 1 1 1 0 Putative amidoligase enzyme Lambda_CIII PF02061.11 EMR63998.1 - 0.076 13.0 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Lambda Phage CIII Peptidase_M64 PF09471.5 EMR63999.1 - 8.3e-18 64.9 0.0 2e-11 44.0 0.0 2.2 1 1 1 2 2 2 2 IgA Peptidase M64 DUF2970 PF11174.3 EMR64000.1 - 0.07 12.7 0.1 0.07 12.7 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) 5TM-5TMR_LYT PF07694.7 EMR64000.1 - 0.1 11.9 5.1 0.11 11.7 3.5 1.0 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Ferric_reduct PF01794.14 EMR64000.1 - 0.15 12.1 3.5 1.7 8.7 0.2 2.1 1 1 1 2 2 2 0 Ferric reductase like transmembrane component DUF805 PF05656.9 EMR64000.1 - 0.85 9.4 3.1 1.1 9.0 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Tetraspannin PF00335.15 EMR64000.1 - 4 6.6 7.1 5.2 6.2 4.9 1.2 1 0 0 1 1 1 0 Tetraspanin family Nop14 PF04147.7 EMR64001.1 - 0.2 9.5 10.2 0.33 8.8 7.1 1.3 1 0 0 1 1 1 0 Nop14-like family AT_hook PF02178.14 EMR64001.1 - 1.8 8.4 14.9 1.2 9.0 5.7 2.7 2 0 0 2 2 2 0 AT hook motif Pro_isomerase PF00160.16 EMR64002.1 - 3.1e-48 163.8 0.0 3.6e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sgf11 PF08209.6 EMR64003.1 - 1.4 8.2 8.2 0.23 10.8 2.2 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Acyl_transf_3 PF01757.17 EMR64004.1 - 1.2e-20 73.6 18.5 1.8e-20 73.0 12.8 1.3 1 0 0 1 1 1 1 Acyltransferase family TFIIS_C PF01096.13 EMR64005.1 - 3.5e-19 68.1 0.9 3.5e-19 68.1 0.6 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EMR64005.1 - 0.0036 16.9 1.1 0.011 15.4 0.2 2.0 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Elf1 PF05129.8 EMR64005.1 - 0.031 13.9 0.9 4.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like CN_hydrolase PF00795.17 EMR64006.1 - 7.4e-20 71.0 0.0 1e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FDC-SP PF15215.1 EMR64007.1 - 0.45 10.8 5.4 0.51 10.6 1.8 2.4 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide Med31 PF05669.7 EMR64009.1 - 4.8e-37 125.8 2.8 5.4e-37 125.6 1.9 1.0 1 0 0 1 1 1 1 SOH1 SMC_N PF02463.14 EMR64010.1 - 1.2e-25 89.9 0.0 4.7e-25 88.1 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMR64010.1 - 1.1e-11 45.4 59.5 1.8e-11 44.7 17.8 5.2 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.1 EMR64010.1 - 7.3e-06 26.1 0.4 0.0011 18.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain Reo_sigmaC PF04582.7 EMR64010.1 - 0.00099 18.3 13.3 0.012 14.7 0.7 4.8 2 2 2 5 5 5 1 Reovirus sigma C capsid protein AAA_29 PF13555.1 EMR64010.1 - 0.0072 15.8 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EMR64010.1 - 0.01 15.2 0.9 0.077 12.3 0.0 2.9 2 2 0 2 2 2 0 AAA domain AAA PF00004.24 EMR64010.1 - 0.025 14.7 0.0 0.39 10.9 0.0 3.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR64010.1 - 0.076 13.1 4.4 1.7 8.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain Lipl32 PF12103.3 EMR64010.1 - 0.17 11.2 0.7 0.84 9.0 0.5 2.1 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order IFT46_B_C PF12317.3 EMR64010.1 - 1.2 8.5 16.3 0.09 12.1 0.2 3.8 3 0 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal AAA_16 PF13191.1 EMR64010.1 - 9.2 6.2 12.6 0.53 10.2 0.2 3.7 3 2 0 3 3 3 0 AAA ATPase domain Acetyltransf_1 PF00583.19 EMR64011.1 - 7.6e-06 25.8 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR64011.1 - 0.047 13.8 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EMR64012.1 - 1.9e-30 105.8 27.6 1.9e-30 105.8 19.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1286 PF06939.6 EMR64012.1 - 0.055 13.6 0.5 0.23 11.6 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1286) AA_permease_2 PF13520.1 EMR64013.1 - 1.4e-47 162.2 51.1 3.2e-34 118.1 23.8 2.0 2 0 0 2 2 2 2 Amino acid permease Peptidase_A22B PF04258.8 EMR64014.1 - 3.8e-49 167.7 3.0 3e-48 164.8 2.1 2.1 1 1 0 1 1 1 1 Signal peptide peptidase DEC-1_C PF04626.8 EMR64014.1 - 0.5 10.5 4.1 0.82 9.8 2.8 1.3 1 0 0 1 1 1 0 Dec-1 protein, C terminal region UPF0233 PF06781.7 EMR64014.1 - 0.62 9.7 0.0 0.62 9.7 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) Ank_2 PF12796.2 EMR64015.1 - 1.2e-10 41.5 0.0 2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMR64015.1 - 9.1e-09 34.7 0.1 0.023 14.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.25 EMR64015.1 - 1e-08 34.5 0.1 0.096 12.5 0.0 4.0 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EMR64015.1 - 3.3e-08 33.8 0.1 6.7e-06 26.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR64015.1 - 5e-07 29.7 1.2 0.074 13.3 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PBP1_TM PF14812.1 EMR64015.1 - 1.2 9.4 5.8 2.7 8.3 4.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Lyase_1 PF00206.15 EMR64016.1 - 5e-110 367.5 0.0 6.7e-110 367.1 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EMR64016.1 - 2.1e-22 78.9 0.0 5.4e-22 77.6 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus HET PF06985.6 EMR64018.1 - 5.5e-30 104.3 0.4 5.5e-30 104.3 0.3 2.4 2 2 1 3 3 3 1 Heterokaryon incompatibility protein (HET) Malate_synthase PF01274.17 EMR64019.1 - 1.7e-233 775.3 0.0 2e-233 775.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HSP70 PF00012.15 EMR64020.1 - 2.4e-10 39.0 0.3 3e-09 35.3 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EMR64020.1 - 0.0029 17.2 0.1 0.0069 16.0 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger Hexokinase_1 PF00349.16 EMR64021.1 - 5.1e-65 218.6 0.0 7.5e-65 218.1 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EMR64021.1 - 2.1e-63 213.7 0.0 3.9e-63 212.9 0.0 1.4 1 1 0 1 1 1 1 Hexokinase adh_short PF00106.20 EMR64021.1 - 0.016 15.1 1.0 0.024 14.5 0.2 1.6 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 EMR64021.1 - 0.016 14.8 0.1 0.031 13.9 0.1 1.3 1 0 0 1 1 1 0 KR domain HHH PF00633.18 EMR64021.1 - 0.2 11.4 1.1 7 6.5 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sugar_tr PF00083.19 EMR64022.1 - 3.3e-81 273.1 25.0 5.7e-45 153.7 4.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR64022.1 - 1.5e-27 96.3 36.2 1e-25 90.2 20.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR64022.1 - 2.9e-06 25.7 4.0 2.9e-06 25.7 2.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Fringe PF02434.11 EMR64023.1 - 2e-08 33.7 0.1 6.7e-07 28.7 0.0 2.2 1 1 0 1 1 1 1 Fringe-like Hexapep PF00132.19 EMR64024.1 - 1.1e-09 37.3 21.1 6e-06 25.5 2.0 4.3 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMR64024.1 - 0.00012 21.6 0.7 0.00012 21.6 0.5 3.1 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EMR64024.1 - 0.07 11.6 0.1 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase 4HBT_2 PF13279.1 EMR64025.1 - 1e-07 32.4 0.0 1.8e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily FliT PF05400.8 EMR64026.1 - 0.024 15.0 1.3 0.033 14.5 0.1 1.7 2 0 0 2 2 2 0 Flagellar protein FliT Dmrt1 PF12374.3 EMR64026.1 - 0.05 13.9 4.6 0.074 13.4 3.2 1.3 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 Glyco_hydro_43 PF04616.9 EMR64028.1 - 1.5e-24 86.5 0.2 2.1e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 TMEM51 PF15345.1 EMR64029.1 - 4.8 6.8 7.0 8 6.0 4.9 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 CFEM PF05730.6 EMR64030.1 - 7.6e-11 41.6 14.3 1.3e-10 40.9 9.9 1.4 1 0 0 1 1 1 1 CFEM domain DAP10 PF07213.6 EMR64030.1 - 5.7 6.7 6.4 1.3 8.8 0.1 2.5 2 0 0 2 2 2 0 DAP10 membrane protein EcKinase PF02958.15 EMR64032.1 - 1.4e-20 73.6 0.0 1.6e-18 66.9 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EMR64032.1 - 8.3e-10 37.8 0.0 7.8e-09 34.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) APH PF01636.18 EMR64032.1 - 1e-08 35.2 0.1 1.4e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EMR64032.1 - 0.0013 17.7 0.0 0.37 9.7 0.0 2.2 2 0 0 2 2 2 2 Fructosamine kinase GTP_cyclohydro2 PF00925.15 EMR64033.1 - 4e-55 185.6 0.0 1.3e-52 177.4 0.0 2.1 1 1 0 2 2 2 2 GTP cyclohydrolase II COesterase PF00135.23 EMR64034.1 - 4.6e-53 180.7 0.0 1.4e-43 149.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR64034.1 - 5.2e-09 35.9 0.0 9.1e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR64034.1 - 0.002 17.9 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Arf PF00025.16 EMR64035.1 - 5.9e-74 247.0 0.4 6.9e-74 246.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EMR64035.1 - 2.8e-13 49.5 0.0 3.3e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EMR64035.1 - 5.5e-13 48.3 2.4 8.5e-10 37.8 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EMR64035.1 - 1.7e-12 46.9 0.1 2.1e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EMR64035.1 - 6.8e-11 41.7 0.1 8.1e-11 41.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMR64035.1 - 6.5e-08 33.0 0.0 8.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMR64035.1 - 0.00024 21.0 0.0 0.00033 20.5 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EMR64035.1 - 0.028 13.4 0.2 0.056 12.5 0.2 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 EMR64035.1 - 0.11 12.3 0.2 1 9.2 0.2 2.2 1 1 0 1 1 1 0 AAA domain p450 PF00067.17 EMR64036.1 - 1.1e-59 202.1 0.0 1.5e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PMI_typeI PF01238.16 EMR64037.1 - 1.2e-140 468.7 0.0 1.4e-140 468.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I RRM_1 PF00076.17 EMR64038.1 - 8.7e-15 54.1 0.0 1.4e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR64038.1 - 2e-11 43.7 0.0 4e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 EMR64038.1 - 1.1e-10 41.9 0.0 1.9e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_5 PF13893.1 EMR64038.1 - 1.9e-08 34.0 0.0 3.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDUF_B7 PF05676.8 EMR64039.1 - 2.5e-31 106.8 2.7 2.9e-31 106.6 1.8 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EMR64039.1 - 0.0025 17.5 1.5 0.0034 17.1 1.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like zinc_ribbon_4 PF13717.1 EMR64041.1 - 0.047 13.3 0.1 0.091 12.4 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EMR64041.1 - 0.052 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DUF629 PF04780.7 EMR64041.1 - 0.086 11.3 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.1 EMR64041.1 - 0.12 12.3 0.4 0.17 11.8 0.3 1.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EMR64041.1 - 0.14 12.5 0.5 0.24 11.8 0.3 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger Asp_Glu_race PF01177.17 EMR64042.1 - 7.4e-17 61.9 0.0 9.3e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Pkinase PF00069.20 EMR64043.1 - 2.6e-62 210.3 0.0 3.7e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64043.1 - 1.2e-30 106.4 0.0 1.9e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR64043.1 - 0.00014 20.9 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMR64043.1 - 0.046 13.4 0.0 0.24 11.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family SHS2_Rpb7-N PF03876.12 EMR64044.1 - 0.00038 20.5 0.0 0.00076 19.5 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Parvo_coat PF00740.13 EMR64044.1 - 5.6 5.8 11.9 1.2 8.0 5.4 1.7 2 0 0 2 2 2 0 Parvovirus coat protein VP2 NmrA PF05368.8 EMR64045.1 - 4.1e-31 108.0 0.0 4.9e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR64045.1 - 3.1e-08 33.8 0.0 2.9e-07 30.6 0.0 2.2 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EMR64045.1 - 3.3e-06 26.7 0.0 0.00054 19.4 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR64045.1 - 5.2e-06 25.3 0.0 9.9e-06 24.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EMR64045.1 - 0.0062 16.2 0.0 0.0095 15.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMR64045.1 - 0.011 14.6 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EMR64045.1 - 0.013 15.7 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Actin PF00022.14 EMR64046.1 - 8.7e-116 386.5 0.0 1.1e-115 386.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMR64046.1 - 0.025 13.2 0.0 0.14 10.6 0.0 2.0 1 1 0 1 1 1 0 MreB/Mbl protein DUF1325 PF07039.6 EMR64048.1 - 3.2e-22 78.5 1.5 3.4e-21 75.1 0.0 2.6 2 0 0 2 2 2 1 SGF29 tudor-like domain FAD_binding_3 PF01494.14 EMR64050.1 - 1.4e-14 53.9 0.4 1.4e-06 27.6 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMR64050.1 - 0.00029 20.7 0.0 0.00098 19.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMR64050.1 - 0.012 16.0 0.0 0.029 14.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NACHT PF05729.7 EMR64051.1 - 8.3e-09 35.3 0.0 1.6e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 EMR64051.1 - 0.0049 17.1 1.0 0.38 11.0 0.7 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR64051.1 - 0.005 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EMR64051.1 - 0.0062 15.4 0.0 0.0082 15.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 EMR64051.1 - 0.013 15.7 0.2 0.053 13.7 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EMR64051.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 EMR64051.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EMR64051.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EMR64051.1 - 0.11 12.1 0.0 0.51 9.9 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_17 PF13207.1 EMR64051.1 - 0.16 12.8 1.0 1.1 10.1 0.7 2.3 1 1 0 1 1 1 0 AAA domain Peptidase_S28 PF05577.7 EMR64052.1 - 2.5e-46 158.1 4.6 2.3e-35 121.9 0.2 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Oxidored_FMN PF00724.15 EMR64053.1 - 2e-51 175.0 0.0 2.8e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EMR64053.1 - 0.07 11.9 0.0 0.34 9.6 0.0 2.1 2 1 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF561 PF04481.7 EMR64053.1 - 0.19 10.6 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) EF-hand_1 PF00036.27 EMR64054.1 - 1.9e-11 42.3 0.5 0.03 13.6 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EMR64054.1 - 3.9e-09 36.5 0.1 0.0007 19.6 0.1 3.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 EMR64054.1 - 9.6e-08 31.3 3.5 0.27 11.2 0.2 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EMR64054.1 - 0.00028 20.4 0.1 4.9 6.8 0.0 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EMR64054.1 - 0.00031 19.9 2.7 2.5 7.5 0.0 4.1 4 0 0 4 4 4 2 EF hand Glyco_transf_90 PF05686.7 EMR64055.1 - 1.3e-10 40.5 0.0 9.7e-10 37.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 90 SR-25 PF10500.4 EMR64055.1 - 0.0002 20.9 40.9 0.019 14.4 1.2 3.2 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein DUF3446 PF11928.3 EMR64055.1 - 0.011 15.9 30.8 0.54 10.4 4.9 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) Macoilin PF09726.4 EMR64055.1 - 0.35 9.1 10.2 0.015 13.6 1.5 2.0 2 0 0 2 2 2 0 Transmembrane protein dCMP_cyt_deam_1 PF00383.17 EMR64056.1 - 1.1e-22 79.5 1.9 1.7e-22 79.0 1.3 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 EMR64056.1 - 3.8e-05 24.4 0.1 0.00016 22.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMR64056.1 - 0.0037 17.5 0.0 0.018 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMR64056.1 - 0.035 13.9 0.1 0.068 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain zf-RING_2 PF13639.1 EMR64057.1 - 0.027 14.2 7.6 0.07 12.9 5.3 1.8 1 1 0 1 1 1 0 Ring finger domain Ank PF00023.25 EMR64057.1 - 0.035 13.9 0.1 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat zf-ribbon_3 PF13248.1 EMR64057.1 - 0.06 12.5 0.1 0.18 11.0 0.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain zf-C3HC4_4 PF15227.1 EMR64057.1 - 0.1 12.4 2.6 0.24 11.3 1.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EMR64057.1 - 1.8 8.6 6.9 0.28 11.2 1.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-CSL PF05207.8 EMR64057.1 - 2.1 7.9 5.9 0.26 10.8 1.1 1.6 1 1 0 1 1 1 0 CSL zinc finger DUF1993 PF09351.5 EMR64058.1 - 3.6e-43 147.2 0.0 4e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) NVEALA PF14055.1 EMR64059.1 - 0.1 12.2 1.8 4.1 7.1 0.7 2.1 2 0 0 2 2 2 0 NVEALA protein Proteasome PF00227.21 EMR64060.1 - 3.3e-47 160.2 0.0 4.5e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMR64060.1 - 4.3e-12 45.1 1.2 6.8e-12 44.4 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2011 PF09428.5 EMR64061.1 - 0.001 18.9 0.1 0.0026 17.6 0.1 1.7 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) ORC5_C PF14630.1 EMR64061.1 - 0.028 13.8 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus SIS PF01380.17 EMR64062.1 - 8.8e-14 51.2 0.0 2.8e-13 49.5 0.0 1.9 1 1 0 1 1 1 1 SIS domain DUF2332 PF10094.4 EMR64062.1 - 0.028 13.4 0.1 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) Kinesin PF00225.18 EMR64063.1 - 2.3e-51 174.4 0.0 6.8e-51 172.9 0.0 1.9 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EMR64063.1 - 7.4e-46 155.3 0.0 1.6e-45 154.2 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein KIF1B PF12423.3 EMR64063.1 - 1.8e-06 27.8 1.2 1.8e-06 27.8 0.8 2.0 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.24 EMR64063.1 - 0.00095 19.3 0.0 0.031 14.4 0.0 2.8 2 1 0 2 2 2 1 PH domain Erp_C PF06780.6 EMR64063.1 - 3.8 7.3 17.4 0.021 14.6 4.8 2.5 3 0 0 3 3 3 0 Erp protein C-terminus V_ATPase_I PF01496.14 EMR64063.1 - 4.8 4.9 8.9 0.98 7.1 3.0 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Claudin_2 PF13903.1 EMR64064.1 - 3.2e-05 23.7 4.5 4.8e-05 23.1 3.1 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 EMR64064.1 - 9.4e-05 22.4 0.6 0.00023 21.1 0.4 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Peptidase_U4 PF03419.8 EMR64064.1 - 0.21 10.6 1.2 0.33 9.9 0.8 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Cyt-b5 PF00173.23 EMR64065.1 - 2.1e-17 62.6 0.2 2.3e-17 62.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EFP_N PF08207.7 EMR64065.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain V-ATPase_H_C PF11698.3 EMR64065.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.3 1 1 0 1 1 1 0 V-ATPase subunit H DUF2373 PF10180.4 EMR64066.1 - 3.4e-16 58.5 0.0 7.1e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Serglycin PF04360.7 EMR64066.1 - 0.021 14.5 1.7 0.021 14.5 1.2 2.4 2 1 0 2 2 2 0 Serglycin adh_short PF00106.20 EMR64067.1 - 9.8e-09 35.3 0.0 1.4e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR64067.1 - 8.2e-07 29.0 0.0 1e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EMR64067.1 - 0.0019 17.5 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EMR64067.1 - 0.027 13.8 0.0 0.037 13.4 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 EMR64068.1 - 4.8e-48 163.8 0.0 6.6e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3040 PF11239.3 EMR64068.1 - 5.4 7.1 5.5 4.1 7.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Hormone_4 PF00220.12 EMR64069.1 - 2.4 8.0 9.3 7.8 6.4 0.2 3.7 3 0 0 3 3 3 0 Neurohypophysial hormones, N-terminal Domain Peptidase_M1 PF01433.15 EMR64070.1 - 3.1e-49 168.1 0.0 1.1e-40 139.9 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EMR64070.1 - 2.7e-36 124.3 0.2 6.5e-36 123.0 0.0 1.8 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EMR64070.1 - 8.7e-08 32.2 0.0 1.8e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2697 PF10906.3 EMR64070.1 - 0.019 14.9 0.0 0.054 13.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2697) MFS_1 PF07690.11 EMR64072.1 - 3e-28 98.5 31.7 3e-28 98.5 22.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR64072.1 - 3.6e-21 75.2 21.8 7.1e-17 61.1 4.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter ThiF PF00899.16 EMR64073.1 - 1.8e-27 95.8 0.0 4.7e-27 94.4 0.0 1.7 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 EMR64073.1 - 0.026 14.6 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_M20 PF01546.23 EMR64074.1 - 1.5e-15 57.2 0.0 3.4e-15 56.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMR64074.1 - 2.7e-09 36.7 0.2 6.6e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Uds1 PF15456.1 EMR64075.1 - 8.3e-22 77.4 5.0 2.4e-15 56.6 1.5 2.6 1 1 1 2 2 2 2 Up-regulated During Septation PAP_central PF04928.12 EMR64075.1 - 0.01 14.6 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain DUF1140 PF06600.6 EMR64075.1 - 0.034 14.2 0.5 0.059 13.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) FtsJ PF01728.14 EMR64076.1 - 4.8e-42 143.9 0.0 6e-41 140.4 0.0 2.0 1 1 1 2 2 2 2 FtsJ-like methyltransferase VCBS PF13517.1 EMR64077.1 - 0.64 10.4 8.7 5.7 7.3 0.3 5.0 3 2 3 6 6 6 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella ABC_tran PF00005.22 EMR64078.1 - 8.5e-62 207.4 0.0 2.2e-31 108.9 0.0 2.7 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMR64078.1 - 6.5e-55 186.4 30.3 1.1e-33 116.8 9.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EMR64078.1 - 1.7e-15 56.8 0.5 7.6e-05 22.0 0.0 4.0 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMR64078.1 - 1.1e-11 45.1 0.1 3.6e-05 23.8 0.0 3.5 4 0 0 4 4 4 2 AAA ATPase domain AAA_21 PF13304.1 EMR64078.1 - 1.1e-10 41.9 0.0 0.072 13.0 0.0 4.2 2 2 1 3 3 3 3 AAA domain AAA_29 PF13555.1 EMR64078.1 - 8.2e-09 34.8 0.6 0.00012 21.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EMR64078.1 - 5.4e-08 33.6 0.0 0.0095 16.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMR64078.1 - 1.1e-07 32.0 1.2 0.053 13.6 0.1 3.8 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMR64078.1 - 1.7e-07 30.5 0.0 0.01 15.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EMR64078.1 - 3.1e-07 30.1 0.4 0.023 14.1 0.0 3.9 4 0 0 4 4 3 2 AAA-like domain ABC_ATPase PF09818.4 EMR64078.1 - 3.3e-07 29.2 0.3 0.005 15.4 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA PF00004.24 EMR64078.1 - 1.1e-06 28.8 0.4 1.3 9.2 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EMR64078.1 - 1.5e-05 25.2 0.0 0.27 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EMR64078.1 - 2.7e-05 23.8 0.2 0.93 9.0 0.0 3.8 4 0 0 4 4 4 2 AAA domain SbcCD_C PF13558.1 EMR64078.1 - 4.7e-05 23.2 1.5 0.24 11.3 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EMR64078.1 - 8.3e-05 22.4 0.0 0.37 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EMR64078.1 - 0.0001 22.0 0.2 1.3 8.7 0.0 3.6 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 EMR64078.1 - 0.00017 21.1 0.1 0.33 10.4 0.0 3.2 3 1 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 EMR64078.1 - 0.00025 19.8 0.0 0.025 13.2 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 EMR64078.1 - 0.0004 19.8 0.3 1.9 7.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 EMR64078.1 - 0.00042 20.0 0.0 0.41 10.3 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EMR64078.1 - 0.00042 20.0 0.2 2.1 8.1 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain AAA_23 PF13476.1 EMR64078.1 - 0.00068 20.0 0.2 1.5 9.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.17 EMR64078.1 - 0.00086 18.7 0.0 1.4 8.2 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_28 PF13521.1 EMR64078.1 - 0.0012 18.7 0.0 0.39 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EMR64078.1 - 0.0031 16.9 1.1 2.4 7.5 0.0 3.4 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EMR64078.1 - 0.0045 17.1 0.0 1.3 9.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 EMR64078.1 - 0.0057 16.5 0.0 6 6.7 0.0 3.8 4 0 0 4 4 4 0 AAA domain ATP_bind_1 PF03029.12 EMR64078.1 - 0.0058 16.1 0.1 0.64 9.5 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Synapsin_N PF10581.4 EMR64078.1 - 0.012 15.3 0.0 0.55 10.1 0.0 2.4 2 0 0 2 2 2 0 Synapsin N-terminal APS_kinase PF01583.15 EMR64078.1 - 0.068 12.8 0.0 15 5.1 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.13 EMR64078.1 - 0.078 12.5 0.0 3.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 EMR64078.1 - 0.089 11.6 0.1 2 7.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.18 EMR64078.1 - 0.13 12.2 0.3 30 4.5 0.0 3.0 4 0 0 4 4 2 0 50S ribosome-binding GTPase AAA_24 PF13479.1 EMR64078.1 - 0.13 11.8 0.1 9.2 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 EMR64079.1 - 1.4e-18 66.7 29.5 1.4e-18 66.7 20.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily CENP-B_N PF04218.8 EMR64079.1 - 0.0072 15.7 0.1 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain DUF3708 PF12501.3 EMR64079.1 - 0.0083 15.9 0.1 0.023 14.5 0.1 1.8 1 0 0 1 1 1 1 Phosphate ATP-binding cassette transporter DUF2681 PF10883.3 EMR64079.1 - 0.42 10.8 2.1 4.8 7.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Amidase PF01425.16 EMR64080.1 - 1.8e-27 96.2 0.0 3.5e-23 82.1 0.0 2.8 2 1 1 3 3 3 2 Amidase Kinesin PF00225.18 EMR64081.1 - 6.6e-41 140.1 0.0 1.4e-40 139.0 0.0 1.4 1 1 0 1 1 1 1 Kinesin motor domain DUF87 PF01935.12 EMR64081.1 - 0.14 11.9 0.3 0.37 10.5 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function DUF87 Methyltransf_23 PF13489.1 EMR64082.1 - 7.5e-13 48.5 0.0 9.1e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR64082.1 - 6.9e-09 36.2 0.0 7e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR64082.1 - 8.5e-08 31.9 0.0 2.8e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR64082.1 - 0.00078 19.7 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR64082.1 - 0.0018 18.6 0.0 0.0088 16.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMR64082.1 - 0.0043 16.1 0.0 0.0071 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EMR64082.1 - 0.01 14.9 0.0 0.013 14.5 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EMR64082.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EMR64082.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 EMR64082.1 - 0.026 14.5 0.0 0.05 13.5 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Peptidase_M48 PF01435.13 EMR64083.1 - 9.2e-38 130.0 0.0 1.3e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 HSP70 PF00012.15 EMR64084.1 - 9.2e-08 30.4 0.1 7.7e-07 27.4 0.0 1.9 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMR64084.1 - 0.11 11.0 0.0 0.22 10.0 0.0 1.6 1 0 0 1 1 1 0 MreB/Mbl protein FAD_binding_4 PF01565.18 EMR64085.1 - 1.2e-06 28.0 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Tet_JBP PF12851.2 EMR64086.1 - 0.0098 15.2 0.0 0.024 13.9 0.0 1.6 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Mpv17_PMP22 PF04117.7 EMR64087.1 - 3.4e-09 36.2 1.6 2.3e-08 33.5 1.3 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family Chitin_bind_3 PF03067.10 EMR64088.1 - 6.3e-11 42.8 0.0 9.4e-11 42.3 0.0 1.3 1 1 0 1 1 1 1 Chitin binding domain Myb_DNA-bind_6 PF13921.1 EMR64089.1 - 1.6e-09 37.6 0.1 2.5e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMR64089.1 - 3.8e-05 23.6 0.0 8.8e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Vint PF14623.1 EMR64090.1 - 1.3e-48 164.5 0.0 2.1e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 EMR64090.1 - 1.7e-27 95.3 0.0 3.1e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 EMR64090.1 - 1.2e-20 74.3 0.0 2.8e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EMR64090.1 - 9.9e-17 61.2 0.0 1.6e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EMR64090.1 - 5.6e-13 48.8 0.0 1.8e-10 40.7 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.9 EMR64090.1 - 0.011 14.8 0.0 0.027 13.6 0.0 1.5 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Hint PF01079.15 EMR64090.1 - 0.15 11.2 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 Hint module CorA PF01544.13 EMR64091.1 - 0.039 12.9 1.5 5.5 5.9 0.1 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Methyltransf_18 PF12847.2 EMR64092.1 - 7.5e-11 42.6 0.1 1.2e-10 41.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR64092.1 - 3e-09 36.7 0.0 4.4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR64092.1 - 3.5e-09 37.0 0.0 5.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR64092.1 - 6.9e-09 36.0 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR64092.1 - 1.3e-08 34.8 0.0 2.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR64092.1 - 7.9e-08 32.5 0.0 1.2e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR64092.1 - 1.9e-06 27.1 0.0 2.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EMR64092.1 - 0.00017 20.8 0.0 0.00024 20.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EMR64092.1 - 0.00019 21.0 0.0 0.00037 20.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR64092.1 - 0.00023 20.5 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 EMR64092.1 - 0.00065 19.1 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) NAD_synthase PF02540.12 EMR64093.1 - 1.4e-10 40.4 0.0 2.2e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 NAD synthase GATase PF00117.23 EMR64093.1 - 9e-06 25.2 0.0 2.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Asn_synthase PF00733.16 EMR64093.1 - 1.7e-05 24.4 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.15 EMR64093.1 - 0.0001 21.8 0.0 0.00032 20.2 0.0 1.7 2 0 0 2 2 2 1 PP-loop family QueC PF06508.8 EMR64093.1 - 0.00026 20.3 0.0 0.0017 17.6 0.0 1.9 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.14 EMR64093.1 - 0.0029 17.4 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.9 EMR64093.1 - 0.003 17.0 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 EMR64093.1 - 0.0058 15.2 0.1 0.0097 14.4 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase SRF-TF PF00319.13 EMR64094.1 - 8.3e-24 82.5 0.4 1.2e-23 82.1 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 EMR64094.1 - 0.022 12.8 0.4 0.026 12.5 0.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MRI PF15325.1 EMR64094.1 - 2 9.4 4.6 1.6 9.7 0.1 2.4 2 0 0 2 2 2 0 Modulator of retrovirus infection eIF-1a PF01176.14 EMR64096.1 - 1e-28 98.5 0.1 1.5e-28 98.0 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Gas_vesicle_C PF01304.12 EMR64097.1 - 6.1 6.5 6.8 0.27 10.8 0.7 1.8 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain ERCC4 PF02732.10 EMR64098.1 - 1.1e-23 83.5 0.0 2.2e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain Tetraspannin PF00335.15 EMR64101.1 - 1.9e-05 24.0 7.3 3.1e-05 23.3 5.0 1.3 1 0 0 1 1 1 1 Tetraspanin family p450 PF00067.17 EMR64102.1 - 1e-34 119.8 0.0 1.1e-34 119.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TruB_C PF09142.6 EMR64102.1 - 0.13 11.8 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal PTCB-BRCT PF12738.2 EMR64103.1 - 8.7e-12 44.7 0.0 2.2e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EMR64103.1 - 4e-09 36.4 0.0 7.7e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 EMR64103.1 - 0.00042 20.3 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 EMR64103.1 - 0.0029 17.3 0.1 0.009 15.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) CorA PF01544.13 EMR64104.1 - 0.004 16.2 3.1 0.006 15.6 2.0 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Glycoprotein_B PF00606.13 EMR64105.1 - 0.0054 14.8 2.5 0.0059 14.6 1.7 1.0 1 0 0 1 1 1 1 Herpesvirus Glycoprotein B Vps16_N PF04841.8 EMR64106.1 - 2.4e-97 326.0 0.0 3.7e-97 325.4 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EMR64106.1 - 2.4e-73 246.8 0.0 3.4e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Syntaxin PF00804.20 EMR64107.1 - 0.0061 16.7 0.0 0.064 13.4 0.0 2.1 2 0 0 2 2 2 1 Syntaxin Surfac_D-trimer PF09006.6 EMR64107.1 - 0.27 11.0 1.6 0.43 10.3 0.3 2.0 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation MscS_porin PF12795.2 EMR64107.1 - 0.54 9.5 4.2 0.88 8.8 0.7 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain HET PF06985.6 EMR64108.1 - 1.4e-21 77.1 0.0 2.2e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fcf2 PF08698.6 EMR64109.1 - 4.8e-30 103.5 0.5 1.4e-29 101.9 0.4 1.8 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing DUF4633 PF15464.1 EMR64109.1 - 0.067 13.0 1.5 2.9 7.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) Glyco_hydro_1 PF00232.13 EMR64110.1 - 2.3e-150 500.7 0.0 2.7e-150 500.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Sec15 PF04091.7 EMR64111.1 - 2.7e-101 338.9 6.7 5.2e-101 338.0 1.0 3.1 2 1 1 3 3 3 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.1 EMR64111.1 - 0.00023 20.6 4.7 0.00027 20.4 1.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Mod_r PF07200.8 EMR64111.1 - 1.1 9.1 12.0 0.11 12.4 2.1 3.3 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein B3_4 PF03483.12 EMR64112.1 - 6.4e-25 87.6 0.0 1.2e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EMR64112.1 - 1.4e-15 56.8 0.0 1.5e-12 47.1 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain WD40 PF00400.27 EMR64113.1 - 5.4e-24 83.1 20.6 2.1e-05 24.1 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat MraZ PF02381.13 EMR64113.1 - 0.094 12.4 0.0 18 5.1 0.0 2.5 2 0 0 2 2 2 0 MraZ protein BBS2_N PF14781.1 EMR64113.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal PHTB1_N PF14727.1 EMR64113.1 - 0.23 10.3 0.1 10 4.9 0.0 2.2 1 1 1 2 2 2 0 PTHB1 N-terminus Fructosamin_kin PF03881.9 EMR64114.1 - 2e-25 89.3 0.0 2.6e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EMR64114.1 - 5.2e-15 55.8 0.0 7.4e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMR64114.1 - 0.0066 16.0 0.0 0.0097 15.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EMR64114.1 - 0.011 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase SNF2_N PF00176.18 EMR64115.1 - 1.5e-83 280.0 1.2 1.5e-83 280.0 0.8 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EMR64115.1 - 1.5e-20 72.8 0.1 7.8e-20 70.5 0.0 2.2 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 EMR64115.1 - 3.5e-19 68.4 0.0 2.8e-16 59.1 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 EMR64115.1 - 2e-16 59.8 0.7 2e-16 59.8 0.5 3.3 3 1 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EMR64115.1 - 1.8e-14 53.2 12.6 1.8e-14 53.2 8.7 3.7 5 0 0 5 5 5 1 HSA QLQ PF08880.6 EMR64115.1 - 6e-09 35.1 8.0 6e-09 35.1 5.6 3.4 3 0 0 3 3 3 1 QLQ Sad1_UNC PF07738.8 EMR64116.1 - 4.2e-34 117.2 0.0 8e-34 116.3 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CBFD_NFYB_HMF PF00808.18 EMR64117.1 - 1.3e-19 69.9 0.6 1.9e-19 69.4 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMR64117.1 - 2.5e-11 43.5 0.1 3.6e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EMR64117.1 - 0.02 14.6 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X RRM_2 PF04059.7 EMR64118.1 - 2e-32 111.0 0.2 3.1e-32 110.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EMR64118.1 - 0.016 14.8 0.0 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR64119.1 - 3.5e-11 42.9 0.0 6.6e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR64119.1 - 8.4e-11 41.3 0.0 8.4e-11 41.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR64119.1 - 0.00031 20.5 0.0 0.00078 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT PF02985.17 EMR64120.1 - 1.8e-43 142.6 18.5 0.0029 17.5 0.1 13.2 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 EMR64120.1 - 9.5e-31 105.9 2.9 1e-07 32.1 0.0 7.7 3 3 5 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.2 EMR64120.1 - 9e-11 42.0 2.1 0.0075 16.6 0.1 7.5 5 2 4 9 9 9 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EMR64120.1 - 4.7e-08 31.8 9.5 0.051 11.8 0.1 5.3 3 2 2 6 6 6 4 Adaptin N terminal region HEAT_EZ PF13513.1 EMR64120.1 - 1.1e-06 28.9 14.9 0.22 12.0 0.1 9.1 8 2 2 10 10 10 2 HEAT-like repeat CLASP_N PF12348.3 EMR64120.1 - 0.00025 20.5 1.7 1.5 8.0 0.1 4.5 3 2 1 4 4 4 2 CLASP N terminal DUF2435 PF10363.4 EMR64120.1 - 0.0092 15.8 5.3 3.1 7.7 0.1 4.6 4 1 1 5 5 5 1 Protein of unknown function (DUF2435) Arm PF00514.18 EMR64120.1 - 0.015 15.1 4.6 1.7 8.5 0.0 4.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 EMR64120.1 - 0.022 13.7 0.5 0.21 10.5 0.1 2.6 3 1 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain Proteasom_PSMB PF10508.4 EMR64120.1 - 0.04 12.2 2.8 0.46 8.6 0.0 3.0 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit RIX1 PF08167.7 EMR64120.1 - 0.045 13.4 0.0 0.92 9.1 0.0 3.0 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis Mg_trans_NIPA PF05653.9 EMR64121.1 - 5.2e-36 124.1 0.5 3.8e-32 111.4 0.1 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EMR64121.1 - 0.00014 22.0 1.1 0.00014 22.0 0.7 2.2 3 0 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EMR64121.1 - 0.00055 19.9 2.8 0.00055 19.9 1.9 2.9 3 0 0 3 3 3 1 EamA-like transporter family LRR19-TM PF15176.1 EMR64121.1 - 0.0027 17.3 0.0 0.0061 16.2 0.0 1.6 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain DUF914 PF06027.7 EMR64121.1 - 0.013 14.3 0.4 0.018 13.8 0.3 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) NicO PF03824.11 EMR64121.1 - 0.03 13.6 0.2 0.22 10.7 0.1 1.9 2 0 0 2 2 2 0 High-affinity nickel-transport protein Polysacc_synt_C PF14667.1 EMR64121.1 - 0.062 13.0 4.3 0.082 12.7 1.3 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Shisa PF13908.1 EMR64121.1 - 0.13 12.4 0.0 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Myotub-related PF06602.9 EMR64123.1 - 4.6e-85 285.5 0.0 6.8e-85 284.9 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EMR64123.1 - 0.019 15.2 0.0 0.054 13.7 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 EMR64123.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Methyltransf_18 PF12847.2 EMR64124.1 - 6.8e-12 45.9 0.1 1.3e-11 45.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR64124.1 - 5e-10 39.1 0.0 7e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EMR64124.1 - 2.5e-05 24.2 0.0 5.4e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR64124.1 - 0.00036 20.9 0.4 0.00096 19.5 0.3 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR64124.1 - 0.0048 17.2 0.0 0.009 16.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMR64124.1 - 0.0071 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR64124.1 - 0.011 16.2 0.1 0.027 14.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DUF162 PF02589.10 EMR64124.1 - 0.023 14.1 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 ADH_N PF08240.7 EMR64126.1 - 2.6e-28 97.9 0.1 7.4e-28 96.4 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR64126.1 - 2.7e-22 78.7 0.5 3.8e-22 78.2 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR64126.1 - 2e-05 25.4 0.0 3.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.11 EMR64127.1 - 6.9e-13 48.0 62.0 1.5e-11 43.6 40.5 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyoxalase_2 PF12681.2 EMR64128.1 - 1e-05 26.0 1.1 0.5 10.9 0.0 3.1 2 1 1 3 3 3 3 Glyoxalase-like domain Glyoxalase PF00903.20 EMR64128.1 - 9.3e-05 22.4 0.7 0.0014 18.6 0.4 2.4 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EMR64128.1 - 0.014 15.3 0.3 0.23 11.4 0.0 2.7 2 2 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pyr_redox_2 PF07992.9 EMR64131.1 - 2.2e-08 34.2 0.1 1.7e-07 31.3 0.1 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR64131.1 - 0.00029 19.8 1.1 0.0022 16.9 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMR64131.1 - 0.00071 19.3 0.0 0.0085 15.8 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EMR64131.1 - 0.00087 18.0 0.8 0.0026 16.4 0.2 2.0 3 0 0 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EMR64131.1 - 0.0074 15.2 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMR64131.1 - 0.013 15.5 0.1 0.049 13.6 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR64131.1 - 0.019 14.9 0.0 0.054 13.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain PTR2 PF00854.16 EMR64132.1 - 7e-08 31.6 0.3 9.9e-08 31.1 0.2 1.2 1 0 0 1 1 1 1 POT family DELLA PF12041.3 EMR64132.1 - 0.024 14.3 0.0 2.2 7.9 0.0 2.9 3 0 0 3 3 3 0 Transcriptional regulator DELLA protein N terminal FAD_binding_3 PF01494.14 EMR64133.1 - 4e-42 144.5 0.0 8.5e-41 140.1 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EMR64133.1 - 7.8e-05 21.8 0.1 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EMR64133.1 - 0.0014 17.5 0.3 0.0021 16.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMR64133.1 - 0.0018 18.1 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR64133.1 - 0.002 18.1 0.1 0.0052 16.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR64133.1 - 0.0064 16.5 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR64133.1 - 0.0065 15.4 0.5 0.019 13.8 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR64133.1 - 0.029 12.8 0.1 0.042 12.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 EMR64133.1 - 0.12 11.2 0.2 0.31 9.8 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EMR64133.1 - 0.14 12.6 0.3 0.55 10.6 0.2 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_PK PF05891.7 EMR64134.1 - 1e-81 273.4 0.0 1.1e-81 273.2 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 EMR64134.1 - 6.8e-05 23.4 0.0 0.0001 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR64134.1 - 9.9e-05 22.1 0.0 0.00016 21.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR64134.1 - 0.0012 19.2 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR64134.1 - 0.0085 16.5 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMR64134.1 - 0.1 11.6 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF221 PF02714.10 EMR64135.1 - 3.6e-93 311.9 17.0 4.6e-93 311.6 11.8 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF4463 PF14703.1 EMR64135.1 - 8.3e-18 64.6 0.0 1.4e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Anoctamin PF04547.7 EMR64135.1 - 0.00078 18.2 1.6 0.0017 17.0 1.1 1.5 1 0 0 1 1 1 1 Calcium-activated chloride channel RRM_6 PF14259.1 EMR64135.1 - 0.0043 17.0 0.1 0.87 9.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR64135.1 - 0.087 12.6 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_20 PF00982.16 EMR64136.1 - 1.4e-160 534.8 0.1 2.1e-160 534.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EMR64136.1 - 1.2e-42 145.4 0.0 2.2e-42 144.6 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 EMR64136.1 - 0.084 12.3 0.4 0.18 11.2 0.3 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain Lactonase PF10282.4 EMR64137.1 - 1.7e-17 63.5 0.0 7.9e-17 61.3 0.0 1.8 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.6 EMR64137.1 - 0.056 12.3 0.1 0.12 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) Sugar_tr PF00083.19 EMR64138.1 - 4.4e-91 305.7 25.5 5.1e-91 305.5 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR64138.1 - 4e-20 71.8 38.5 2e-17 62.9 18.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR64138.1 - 8.3e-05 20.9 1.5 0.00019 19.8 1.1 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EMR64139.1 - 1.6e-33 115.8 21.4 2e-33 115.5 14.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR64139.1 - 2.6e-13 49.3 16.6 5.6e-13 48.2 11.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter NfeD PF01957.13 EMR64139.1 - 3.7 7.6 15.6 0.78 9.8 0.5 3.9 2 2 2 4 4 4 0 NfeD-like C-terminal, partner-binding PIF1 PF05970.9 EMR64140.1 - 1.2e-29 103.4 0.0 1.8e-17 63.3 0.0 2.6 2 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EMR64140.1 - 1.6e-09 37.6 0.0 1.8e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain Herpes_Helicase PF02689.9 EMR64140.1 - 1.3e-06 26.5 0.0 1.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EMR64140.1 - 8.4e-05 22.6 0.1 0.00025 21.1 0.0 1.9 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EMR64140.1 - 0.0076 15.7 0.0 0.076 12.5 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase OrfB_Zn_ribbon PF07282.6 EMR64140.1 - 0.1 12.3 0.2 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Peptidase_S8 PF00082.17 EMR64141.1 - 5.8e-19 68.3 4.1 3e-17 62.7 2.5 2.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMR64141.1 - 2.6e-12 47.1 0.4 4.4e-12 46.3 0.3 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 EcKinase PF02958.15 EMR64142.1 - 7.4e-15 54.8 0.0 1.2e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.18 EMR64142.1 - 8.5e-08 32.2 0.2 8.5e-08 32.2 0.1 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family AA_permease_2 PF13520.1 EMR64143.1 - 2.3e-96 322.9 36.0 2.3e-96 322.9 25.0 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMR64143.1 - 2e-21 75.9 30.3 4e-21 74.9 21.0 1.4 1 1 0 1 1 1 1 Amino acid permease adh_short PF00106.20 EMR64145.1 - 1e-25 90.5 6.4 2.3e-25 89.4 4.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR64145.1 - 7.3e-15 55.3 0.0 9e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR64145.1 - 6.9e-08 32.3 1.5 1.2e-07 31.5 1.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMR64145.1 - 6.9e-08 31.9 0.0 3e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EMR64145.1 - 0.0004 20.4 3.0 0.0011 19.0 2.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR64145.1 - 0.0038 16.5 0.6 0.0053 16.0 0.3 1.4 1 1 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.15 EMR64145.1 - 0.028 14.5 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 EMR64145.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_18 PF12847.2 EMR64145.1 - 0.18 12.3 1.0 0.85 10.2 0.7 2.1 1 1 0 1 1 1 0 Methyltransferase domain Aminotran_4 PF01063.14 EMR64146.1 - 2e-23 83.0 0.0 2.8e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Glyco_hydro_43 PF04616.9 EMR64147.1 - 6.6e-50 169.8 7.3 1.1e-49 169.0 5.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Laminin_G_1 PF00054.18 EMR64147.1 - 0.00069 19.6 0.2 0.0022 18.0 0.0 1.9 3 0 0 3 3 3 1 Laminin G domain Laminin_G_2 PF02210.19 EMR64147.1 - 0.0023 17.9 0.1 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Laminin G domain CBM_4_9 PF02018.12 EMR64147.1 - 0.0038 17.2 1.4 2.8 7.9 0.1 2.7 2 0 0 2 2 2 2 Carbohydrate binding domain MutS_V PF00488.16 EMR64148.1 - 2.9e-18 66.1 0.1 2.5e-11 43.4 0.2 2.2 1 1 1 2 2 2 2 MutS domain V MutS_V PF00488.16 EMR64149.1 - 1.5e-76 256.9 0.0 1.5e-75 253.5 0.0 2.2 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMR64149.1 - 1.5e-39 135.8 3.7 3.3e-39 134.7 2.6 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EMR64149.1 - 2.7e-28 98.2 0.0 6.1e-28 97.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EMR64149.1 - 9.3e-10 38.6 0.4 8e-09 35.6 0.0 2.7 2 1 1 3 3 3 1 MutS domain II MutS_IV PF05190.13 EMR64149.1 - 4.6e-06 26.7 0.0 1.5e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV MFS_1 PF07690.11 EMR64151.1 - 1.3e-12 47.1 18.6 1.8e-12 46.6 12.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Virul_fac_BrkB PF03631.10 EMR64151.1 - 0.05 12.9 6.8 0.072 12.4 4.0 1.7 1 1 1 2 2 2 0 Virulence factor BrkB Sugar_tr PF00083.19 EMR64151.1 - 0.091 11.3 6.8 0.1 11.1 4.7 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter HPP PF04982.8 EMR64152.1 - 6.8e-38 129.2 5.5 8.9e-38 128.8 3.8 1.1 1 0 0 1 1 1 1 HPP family FAD-oxidase_C PF02913.14 EMR64153.1 - 1.8e-20 73.3 0.0 2.7e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMR64153.1 - 7.9e-15 54.5 0.2 1.6e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_4 PF01565.18 EMR64154.1 - 2.5e-15 56.1 1.1 5.3e-15 55.1 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR64154.1 - 9.1e-10 38.2 0.0 1.7e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like EF-hand_7 PF13499.1 EMR64155.1 - 4.4e-13 49.1 0.2 1.9e-08 34.2 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMR64155.1 - 4e-10 38.7 0.6 0.00085 19.0 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 EMR64155.1 - 7.3e-10 38.6 0.0 0.00026 20.8 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EMR64155.1 - 1.9e-08 32.9 0.4 0.013 14.7 0.0 3.4 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EMR64155.1 - 1.7e-06 27.5 2.2 0.0018 17.8 0.1 3.4 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EMR64155.1 - 0.15 11.4 2.1 2.4 7.6 0.7 2.6 2 0 0 2 2 2 0 EF hand Pyr_redox_3 PF13738.1 EMR64157.1 - 3.6e-22 79.4 0.0 2.6e-21 76.6 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR64157.1 - 8.5e-17 60.5 0.0 5.9e-16 57.7 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EMR64157.1 - 4e-10 39.9 0.0 3e-05 24.0 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR64157.1 - 1e-08 34.4 0.0 9.6e-06 24.7 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMR64157.1 - 2.5e-06 27.3 1.1 2.5e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR64157.1 - 6.4e-06 25.2 0.4 2.2e-05 23.5 0.0 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EMR64157.1 - 0.0001 22.4 0.1 0.046 13.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EMR64157.1 - 0.00012 22.3 5.2 0.05 14.0 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EMR64157.1 - 0.0014 18.2 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EMR64157.1 - 0.013 15.2 0.4 0.15 11.8 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EMR64157.1 - 0.032 12.6 1.5 0.5 8.7 0.2 2.5 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.19 EMR64157.1 - 0.046 12.5 2.9 0.14 10.9 0.8 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 EMR64157.1 - 0.08 13.2 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 EMR64157.1 - 0.12 11.2 1.6 2.1 7.0 0.3 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EMR64157.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EMR64157.1 - 0.65 9.3 2.1 0.64 9.3 0.1 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain p450 PF00067.17 EMR64158.1 - 7.2e-26 90.7 0.6 1.1e-17 63.7 0.6 2.0 1 1 1 2 2 2 2 Cytochrome P450 DHO_dh PF01180.16 EMR64159.1 - 2e-61 207.5 0.0 2.9e-50 170.9 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 EMR64159.1 - 0.017 14.4 1.3 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 PcrB family QCR10 PF09796.4 EMR64160.1 - 1.6e-20 72.4 0.2 2.1e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 EMR64160.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.7 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Peptidase_M3 PF01432.15 EMR64161.1 - 8.6e-123 410.7 0.0 1.2e-122 410.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 EMR64161.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Effector protein DPBB_1 PF03330.13 EMR64162.1 - 6.2e-06 26.1 0.0 1e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EMR64162.1 - 0.00037 20.1 0.2 0.0005 19.7 0.1 1.3 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 EMR64162.1 - 0.011 15.7 0.5 0.022 14.7 0.2 1.6 1 1 1 2 2 2 0 Cerato-platanin Aminotran_3 PF00202.16 EMR64163.1 - 2.5e-48 164.6 2.5 4.1e-47 160.6 1.8 2.0 1 1 0 1 1 1 1 Aminotransferase class-III PhageMin_Tail PF10145.4 EMR64163.1 - 0.069 12.7 0.1 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Phage-related minor tail protein DIOX_N PF14226.1 EMR64164.1 - 6.8e-28 97.5 0.1 1.2e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMR64164.1 - 2.2e-20 72.7 0.0 1.2e-19 70.4 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily OKR_DC_1_N PF03709.10 EMR64164.1 - 0.032 14.2 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Polysacc_deac_1 PF01522.16 EMR64165.1 - 7.3e-25 86.9 0.1 1.1e-24 86.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1996 PF09362.5 EMR64166.1 - 5.2e-73 245.5 5.4 2.5e-37 128.7 2.2 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) EMP70 PF02990.11 EMR64167.1 - 2.1e-197 656.7 2.9 2.7e-197 656.3 2.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 PIRT PF15099.1 EMR64167.1 - 0.22 10.7 1.8 0.52 9.5 1.3 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Transp_cyt_pur PF02133.10 EMR64168.1 - 1.2e-60 205.2 21.0 1.4e-60 205.0 14.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Med4 PF10018.4 EMR64169.1 - 3.7e-39 134.0 0.1 7.1e-39 133.1 0.1 1.5 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 SART-1 PF03343.8 EMR64169.1 - 0.00031 19.2 2.3 0.00031 19.2 1.6 1.5 2 0 0 2 2 2 1 SART-1 family Neuropep_like PF15161.1 EMR64169.1 - 0.03 13.8 0.3 0.48 9.9 0.2 2.3 2 0 0 2 2 2 0 Neuropeptide-like Sporozoite_P67 PF05642.6 EMR64169.1 - 0.12 10.2 16.7 2.3 5.9 0.0 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF4011 PF13195.1 EMR64169.1 - 0.26 11.2 4.0 0.13 12.2 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) DIE2_ALG10 PF04922.7 EMR64170.1 - 1.7e-40 139.2 22.8 1.9e-14 53.4 2.2 4.1 3 1 1 4 4 4 4 DIE2/ALG10 family Mg_trans_NIPA PF05653.9 EMR64171.1 - 3.2e-86 288.9 25.1 4.5e-86 288.5 17.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EMR64171.1 - 4.7e-07 29.9 6.4 4.7e-07 29.9 4.4 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EMR64171.1 - 3e-05 24.0 7.5 3e-05 24.0 5.2 2.8 3 1 0 3 3 3 1 EamA-like transporter family DUF914 PF06027.7 EMR64171.1 - 0.0012 17.7 2.3 0.0012 17.7 1.6 2.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) DUF3292 PF11696.3 EMR64171.1 - 0.22 9.3 0.4 0.37 8.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Sas10_Utp3 PF04000.10 EMR64172.1 - 3.2e-15 56.0 2.8 7.3e-15 54.9 2.0 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family SAGA-Tad1 PF12767.2 EMR64172.1 - 0.18 11.4 2.0 0.52 9.9 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit RNA12 PF10443.4 EMR64173.1 - 6.2e-159 529.1 0.2 7.6e-159 528.8 0.1 1.1 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EMR64173.1 - 1.6e-05 24.7 0.1 0.00013 21.7 0.1 2.2 1 1 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 EMR64173.1 - 2.9e-05 23.6 0.0 0.0003 20.3 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR64173.1 - 0.00035 20.3 0.0 0.00098 18.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 EMR64173.1 - 0.0048 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) AAA_16 PF13191.1 EMR64173.1 - 0.015 15.2 0.2 0.44 10.5 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain RRM_6 PF14259.1 EMR64173.1 - 0.016 15.1 0.0 0.13 12.2 0.0 2.4 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AAA_14 PF13173.1 EMR64173.1 - 0.016 15.1 0.0 0.28 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 EMR64173.1 - 0.047 12.6 0.2 5.2 5.9 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 adh_short PF00106.20 EMR64174.1 - 2.9e-20 72.8 0.3 8.2e-20 71.3 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR64174.1 - 6e-11 42.5 0.0 1.2e-10 41.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR64174.1 - 0.0011 18.6 0.1 0.0015 18.1 0.0 1.4 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 EMR64174.1 - 0.069 12.3 0.2 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EMR64174.1 - 0.1 12.6 0.2 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding BLOC1_2 PF10046.4 EMR64175.1 - 0.16 12.1 0.0 0.76 9.9 0.0 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BNR PF02012.15 EMR64176.1 - 0.088 12.6 0.6 0.32 10.9 0.4 2.0 1 0 0 1 1 1 0 BNR/Asp-box repeat Mo25 PF08569.6 EMR64177.1 - 8e-126 419.5 0.0 9e-126 419.4 0.0 1.0 1 0 0 1 1 1 1 Mo25-like GFA PF04828.9 EMR64178.1 - 2.6e-16 59.3 0.0 3.7e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Laminin_G_3 PF13385.1 EMR64179.1 - 0.028 14.6 0.1 0.26 11.4 0.0 2.4 3 0 0 3 3 3 0 Concanavalin A-like lectin/glucanases superfamily Mito_carr PF00153.22 EMR64180.1 - 1.1e-29 101.9 0.2 1.8e-15 56.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SWIB PF02201.13 EMR64181.1 - 6.7e-12 44.9 0.0 1.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain PBP1_TM PF14812.1 EMR64181.1 - 4.6 7.6 11.3 0.27 11.5 2.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal OPT PF03169.10 EMR64182.1 - 1.2e-142 476.5 18.4 1.4e-142 476.2 12.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RGS PF00615.14 EMR64183.1 - 2.6e-05 24.3 0.0 0.0002 21.4 0.0 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain Tannase PF07519.6 EMR64184.1 - 3e-89 299.9 0.4 1.9e-88 297.2 0.3 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EMR64184.1 - 0.00047 19.9 0.5 0.013 15.2 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR64184.1 - 0.0082 15.3 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF3128 PF11326.3 EMR64186.1 - 6.3e-25 87.1 4.2 9.5e-25 86.5 2.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) tRNA-synt_1 PF00133.17 EMR64187.1 - 2.1e-214 713.0 2.1 3.5e-214 712.2 0.2 2.2 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMR64187.1 - 1e-25 90.2 0.0 5.1e-25 88.0 0.0 2.1 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EMR64187.1 - 1.9e-19 69.5 1.3 2.8e-08 32.8 0.1 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EMR64187.1 - 0.013 14.6 0.0 0.084 11.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain APC_CDC26 PF10471.4 EMR64188.1 - 7.5e-06 26.5 15.1 5.6e-05 23.8 0.0 4.3 4 0 0 4 4 4 3 Anaphase-promoting complex APC subunit 1 DUF1962 PF09227.5 EMR64189.1 - 2.7e-05 24.1 9.5 5e-05 23.2 6.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1962) Toxin_24 PF08094.6 EMR64189.1 - 0.23 11.0 4.2 0.5 10.0 2.9 1.7 1 1 0 1 1 1 0 Conotoxin TVIIA/GS family Pkinase PF00069.20 EMR64190.1 - 1.7e-68 230.6 0.0 2e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64190.1 - 1.5e-35 122.4 0.0 2.4e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR64190.1 - 1.6e-05 24.0 0.4 0.0025 16.8 0.0 2.8 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 EMR64190.1 - 9.8e-05 21.5 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMR64190.1 - 0.00098 18.9 0.1 0.0048 16.6 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EMR64190.1 - 0.045 12.5 0.1 2 7.0 0.0 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EMR64190.1 - 0.075 12.3 0.1 0.2 10.9 0.0 1.8 1 1 0 1 1 1 0 RIO1 family Sugar_tr PF00083.19 EMR64191.1 - 3.9e-85 286.1 34.1 4.6e-85 285.8 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR64191.1 - 1.4e-26 93.0 38.6 1.4e-26 93.0 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR64191.1 - 0.0011 17.2 15.5 0.002 16.4 10.8 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SIR2_2 PF13289.1 EMR64191.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 SIR2-like domain CCSMST1 PF15013.1 EMR64191.1 - 0.25 11.3 0.1 0.25 11.3 0.1 2.2 3 0 0 3 3 3 0 CCSMST1 family Saccharop_dh PF03435.13 EMR64192.1 - 1.2e-21 77.1 0.8 1.6e-21 76.7 0.5 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EMR64192.1 - 3.8e-08 33.5 0.0 7.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding GCV_H PF01597.14 EMR64192.1 - 0.12 12.0 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Glycine cleavage H-protein RNA_pol_Rpc82 PF05645.8 EMR64193.1 - 9.3e-56 189.2 0.0 3.7e-54 183.9 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EMR64193.1 - 0.0066 16.2 3.4 0.06 13.2 0.2 3.6 4 1 1 5 5 5 2 RNA polymerase III subunit RPC82 helix-turn-helix domain Rav1p_C PF12234.3 EMR64194.1 - 6.5e-240 797.6 0.0 1.3e-226 753.7 0.0 2.9 2 1 0 2 2 2 2 RAVE protein 1 C terminal WD40 PF00400.27 EMR64194.1 - 0.023 14.5 0.2 0.8 9.6 0.0 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat ERF PF04404.7 EMR64194.1 - 0.38 10.2 0.0 0.38 10.2 0.0 3.0 4 0 0 4 4 4 0 ERF superfamily adh_short PF00106.20 EMR64195.1 - 5.2e-29 101.2 7.7 1e-28 100.3 5.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR64195.1 - 9.3e-24 84.5 1.8 1.2e-23 84.0 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR64195.1 - 1.3e-15 57.5 4.2 4e-15 55.9 3.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EMR64195.1 - 1.6e-06 27.7 0.6 4.2e-06 26.3 0.4 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ribonucleas_3_3 PF14622.1 EMR64195.1 - 1.3e-05 25.1 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like NAD_binding_10 PF13460.1 EMR64195.1 - 0.0003 20.8 3.4 0.00079 19.4 2.4 1.7 1 1 0 1 1 1 1 NADH(P)-binding Pyridoxal_deC PF00282.14 EMR64195.1 - 0.054 11.9 0.1 0.094 11.1 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Glyco_trans_4_4 PF13579.1 EMR64195.1 - 0.057 13.5 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain HSP70 PF00012.15 EMR64196.1 - 1.3e-269 895.2 5.2 1.4e-269 895.1 3.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMR64196.1 - 2.4e-16 59.2 0.0 3.2e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EMR64196.1 - 0.005 15.9 0.0 0.019 14.0 0.0 1.9 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EMR64196.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EMR64196.1 - 0.03 14.1 2.5 0.93 9.3 1.8 3.3 1 1 0 1 1 1 0 Cell division protein FtsA StbA PF06406.6 EMR64196.1 - 0.062 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 StbA protein PMBR PF09373.5 EMR64196.1 - 0.29 11.1 1.3 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 Pseudomurein-binding repeat Sfi1 PF08457.5 EMR64197.1 - 2.2e-29 102.2 75.0 1.3e-18 66.7 15.3 6.1 4 1 1 6 6 6 5 Sfi1 spindle body protein ADH_zinc_N_2 PF13602.1 EMR64198.1 - 6.5e-11 43.2 0.1 1.5e-10 42.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMR64198.1 - 7.9e-10 38.3 0.0 1.8e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR64198.1 - 5.9e-09 35.6 0.0 1.8e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Dynamin_N PF00350.18 EMR64199.1 - 5.2e-29 101.2 1.8 5.9e-29 101.0 0.0 2.0 3 0 0 3 3 3 1 Dynamin family GED PF02212.13 EMR64199.1 - 1.8e-07 30.9 2.5 3.7e-07 29.9 0.5 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain Miro PF08477.8 EMR64199.1 - 0.0013 19.1 0.0 0.0067 16.9 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Dynamin_M PF01031.15 EMR64199.1 - 0.0016 17.2 0.0 0.0043 15.8 0.0 1.7 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EMR64199.1 - 0.0021 17.9 0.0 0.012 15.5 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.1 EMR64199.1 - 0.0025 17.8 0.0 0.0044 17.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EMR64199.1 - 0.0055 16.9 0.0 0.065 13.5 0.0 2.4 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EMR64199.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pilus_CpaD PF09476.5 EMR64199.1 - 0.021 14.3 0.1 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) AAA_23 PF13476.1 EMR64199.1 - 0.023 15.0 3.5 0.3 11.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMR64199.1 - 0.12 12.3 2.8 15 5.5 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain XPG_I PF00867.13 EMR64200.1 - 4.1e-26 90.8 0.0 1.1e-25 89.4 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EMR64200.1 - 2e-08 34.4 0.0 5.1e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain Actin PF00022.14 EMR64202.1 - 5.5e-08 31.6 0.0 0.0032 15.9 0.0 2.4 2 0 0 2 2 2 2 Actin Med15 PF09606.5 EMR64202.1 - 1.6 6.7 8.0 2.6 6.1 5.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3135 PF11333.3 EMR64203.1 - 0.014 15.5 0.4 1.2 9.3 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3135) DUF3138 PF11336.3 EMR64203.1 - 0.54 8.3 5.3 0.33 9.0 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3138) DUF2795 PF11387.3 EMR64203.1 - 0.87 9.5 20.1 41 4.1 0.2 7.3 3 2 3 7 7 7 0 Protein of unknown function (DUF2795) adh_short PF00106.20 EMR64205.1 - 2.9e-17 63.0 5.3 1.3e-16 61.0 3.7 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR64205.1 - 1.6e-12 47.7 1.1 4.1e-12 46.4 0.7 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR64205.1 - 5.1e-07 29.5 2.2 5.1e-07 29.5 1.5 1.7 2 0 0 2 2 2 1 KR domain TrkA_N PF02254.13 EMR64205.1 - 0.0024 17.8 0.6 0.0041 17.1 0.4 1.3 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.1 EMR64205.1 - 0.0033 17.4 1.0 0.0058 16.6 0.5 1.6 2 0 0 2 2 2 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 EMR64205.1 - 0.0036 16.8 1.1 1.7 8.1 0.9 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.16 EMR64205.1 - 0.0036 16.7 2.7 0.0088 15.5 0.3 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.22 EMR64205.1 - 0.01 16.2 1.7 0.035 14.5 0.9 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3Beta_HSD PF01073.14 EMR64205.1 - 0.013 14.2 0.4 0.019 13.7 0.3 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_tran_WecB PF03808.8 EMR64205.1 - 0.013 14.9 0.2 0.8 9.0 0.2 3.0 2 2 2 4 4 4 0 Glycosyl transferase WecB/TagA/CpsF family 3HCDH_N PF02737.13 EMR64205.1 - 0.032 13.8 2.8 0.05 13.2 2.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EMR64205.1 - 0.06 12.3 0.8 0.081 11.8 0.5 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase HI0933_like PF03486.9 EMR64205.1 - 0.76 8.1 3.4 2.1 6.7 1.5 1.9 1 1 1 2 2 2 0 HI0933-like protein RRM_1 PF00076.17 EMR64206.1 - 2.4e-08 33.4 0.0 2e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR64206.1 - 1e-05 25.3 0.0 0.00012 22.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR64206.1 - 3.6e-05 23.5 0.0 6.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DLH PF01738.13 EMR64207.1 - 3e-18 65.9 0.0 4.5e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMR64207.1 - 0.00012 21.8 0.1 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EMR64207.1 - 0.0021 17.8 0.0 0.0077 15.9 0.0 1.7 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 EMR64207.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) tRNA-synt_2b PF00587.20 EMR64208.1 - 1.5e-59 200.4 0.1 2.4e-59 199.7 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMR64208.1 - 2.4e-20 72.2 0.1 2.4e-20 72.2 0.1 3.0 3 1 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.20 EMR64209.1 - 7.2e-22 77.7 0.0 1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EMR64209.1 - 3.6e-12 46.2 4.0 3.1e-05 23.9 2.4 2.2 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain CAF-1_p150 PF11600.3 EMR64209.1 - 0.00059 19.2 4.9 0.00097 18.5 3.4 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal ERM PF00769.14 EMR64209.1 - 0.053 13.0 8.1 0.067 12.7 5.2 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Ribosomal_L29 PF00831.18 EMR64209.1 - 0.17 11.5 4.9 0.092 12.4 1.7 1.7 2 0 0 2 2 2 0 Ribosomal L29 protein DUF972 PF06156.8 EMR64209.1 - 1.4 9.3 3.6 0.83 10.0 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fungal_trans_2 PF11951.3 EMR64210.1 - 0.00014 20.6 0.2 0.0012 17.4 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Bac_rhamnosid PF05592.6 EMR64211.1 - 2.8e-170 566.9 0.0 3.4e-170 566.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EMR64211.1 - 8.2e-51 171.9 0.9 1.4e-50 171.1 0.1 1.8 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain GTP1_OBG PF01018.17 EMR64212.1 - 2.5e-31 108.4 3.6 7.5e-25 87.4 3.3 4.0 5 0 0 5 5 5 2 GTP1/OBG MMR_HSR1 PF01926.18 EMR64212.1 - 1.8e-19 69.8 0.0 5.2e-19 68.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMR64212.1 - 5.8e-08 32.1 0.0 1.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EMR64212.1 - 0.002 16.9 0.0 0.15 10.8 0.0 2.4 2 0 0 2 2 2 1 ArgK protein GTP_EFTU PF00009.22 EMR64212.1 - 0.02 14.2 0.0 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EMR64212.1 - 0.04 14.2 0.0 0.087 13.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Arf PF00025.16 EMR64212.1 - 0.04 13.1 0.0 0.28 10.3 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF3987 PF13148.1 EMR64212.1 - 0.071 11.6 0.1 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_18 PF13238.1 EMR64212.1 - 0.086 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF3439 PF11921.3 EMR64212.1 - 2.3 7.9 8.2 4.1 7.1 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 EMR64212.1 - 3.2 5.6 7.9 4.6 5.0 5.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MOSC_N PF03476.11 EMR64214.1 - 1.2e-13 50.8 0.0 2.6e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EMR64214.1 - 1.1e-10 41.1 0.0 2.4e-10 39.9 0.0 1.7 1 1 0 1 1 1 1 MOSC domain TFCD_C PF12612.3 EMR64215.1 - 5.2e-13 48.8 0.1 8.4e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal RNA_pol_Rpb5_C PF01191.14 EMR64216.1 - 3.2e-33 113.1 0.6 5.9e-33 112.3 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EMR64216.1 - 1.2e-25 89.7 0.0 2.2e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain CENP-B_N PF04218.8 EMR64216.1 - 0.082 12.3 0.1 11 5.5 0.0 2.5 1 1 1 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_CodY PF08222.6 EMR64216.1 - 0.12 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain eIF3g PF12353.3 EMR64217.1 - 5.5e-46 155.6 5.1 8e-46 155.1 3.5 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EMR64217.1 - 4.2e-15 55.1 0.0 8.2e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR64217.1 - 3.7e-12 46.0 0.1 7.3e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR64217.1 - 2.2e-07 30.6 0.3 4.5e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PEMT PF04191.8 EMR64219.1 - 1.1e-54 183.0 7.8 3.9e-33 113.7 0.5 2.5 2 0 0 2 2 2 2 Phospholipid methyltransferase CBM-like PF14683.1 EMR64221.1 - 8.8e-10 38.4 0.0 1.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EMR64221.1 - 1.3e-08 34.8 0.2 4.4e-08 33.1 0.1 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EMR64221.1 - 0.0013 18.7 0.2 0.14 12.2 0.0 3.0 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Glyco_hydro_76 PF03663.9 EMR64222.1 - 2.4e-43 148.9 12.3 4.8e-43 147.9 8.5 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EMR64222.1 - 0.0028 16.7 0.3 0.04 12.9 0.3 2.2 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Nol1_Nop2_Fmu PF01189.12 EMR64223.1 - 1.3e-30 106.7 0.0 3e-17 62.9 0.0 5.1 4 1 1 5 5 5 5 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EMR64223.1 - 8.6e-05 22.5 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMR64223.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EMR64223.1 - 0.15 11.6 0.0 6.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain DUF3359 PF11839.3 EMR64224.1 - 4.9 7.5 6.8 0.88 9.9 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) Pkinase PF00069.20 EMR64225.1 - 5.8e-73 245.2 0.0 7.3e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64225.1 - 1.4e-31 109.5 0.0 1.9e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMR64225.1 - 1.4e-05 24.2 0.0 5.2e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMR64225.1 - 0.00023 20.2 0.0 0.031 13.2 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EMR64225.1 - 0.00023 20.9 0.1 0.0011 18.7 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMR64225.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FAT PF02259.18 EMR64226.1 - 9.9e-74 248.4 6.4 2.4e-73 247.1 4.4 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EMR64226.1 - 1.3e-26 93.5 0.2 5.8e-26 91.3 0.1 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EMR64226.1 - 9.3e-09 34.5 0.1 3e-08 32.9 0.1 2.0 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 EMR64226.1 - 0.0029 17.2 7.5 8.3 6.1 0.1 4.7 4 0 0 4 4 4 2 TPR repeat HEAT PF02985.17 EMR64226.1 - 0.014 15.4 1.9 8.6 6.7 0.1 4.7 4 0 0 4 4 4 0 HEAT repeat TPR_8 PF13181.1 EMR64226.1 - 0.043 13.5 11.1 0.21 11.4 0.9 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMR64226.1 - 0.053 13.1 7.4 1.8 8.3 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMR64226.1 - 0.13 12.2 9.7 1.9 8.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat NPP1 PF05630.6 EMR64227.1 - 3.3e-78 262.1 2.2 3.8e-78 261.9 1.6 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) AIG2 PF06094.7 EMR64228.1 - 5.7e-16 58.8 0.1 9.6e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family UDPG_MGDP_dh_N PF03721.9 EMR64229.1 - 3.8e-47 160.0 0.0 6.1e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EMR64229.1 - 8.1e-29 99.6 0.0 1.6e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EMR64229.1 - 2.2e-27 95.2 0.0 1.8e-19 69.8 0.0 3.3 2 1 1 3 3 3 3 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.13 EMR64229.1 - 0.0016 18.1 0.0 0.0066 16.1 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMR64229.1 - 0.049 13.3 1.1 0.91 9.2 0.3 2.9 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Epimerase PF01370.16 EMR64230.1 - 1.5e-39 135.8 0.0 1.9e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR64230.1 - 8.9e-11 41.0 0.0 1.1e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMR64230.1 - 3.6e-10 39.1 0.0 2.1e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EMR64230.1 - 4.6e-07 29.0 0.0 3.1e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EMR64230.1 - 5.8e-06 25.4 0.0 0.006 15.5 0.0 2.3 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein Epimerase_Csub PF13950.1 EMR64230.1 - 0.00056 19.7 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit NAD_binding_10 PF13460.1 EMR64230.1 - 0.0012 18.8 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMR64230.1 - 0.0083 16.0 0.0 0.033 14.1 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR64230.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 KR domain Ldh_2 PF02615.9 EMR64231.1 - 2.1e-96 322.6 0.0 2.4e-96 322.3 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase 6PF2K PF01591.13 EMR64232.1 - 2.4e-77 258.9 0.0 3.2e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EMR64232.1 - 3.4e-21 75.9 0.0 7.5e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EMR64232.1 - 9e-10 38.5 0.0 1.4e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EMR64232.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EMR64232.1 - 0.0042 17.8 0.0 0.019 15.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMR64232.1 - 0.073 12.1 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Ribosomal_S4e PF00900.15 EMR64233.1 - 4e-32 109.6 0.2 8.4e-32 108.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EMR64233.1 - 9.8e-18 63.7 4.3 2e-17 62.7 3.0 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EMR64233.1 - 4.1e-05 22.9 0.0 7.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EMR64233.1 - 5.1e-05 22.8 1.6 5.1e-05 22.8 1.1 3.0 4 0 0 4 4 4 1 KOW motif Myb_DNA-binding PF00249.26 EMR64234.1 - 3.5e-13 49.3 0.6 9.9e-07 28.7 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMR64234.1 - 1.6e-11 44.1 1.0 3.1e-05 23.9 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain CHDCT2 PF08074.6 EMR64234.1 - 0.082 12.6 0.6 1.1 8.9 0.0 2.4 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Sugar_tr PF00083.19 EMR64235.1 - 5.5e-78 262.5 24.1 6.8e-78 262.2 16.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Amidohydro_1 PF01979.15 EMR64235.1 - 3.8e-30 105.6 0.0 5.1e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family MFS_1 PF07690.11 EMR64235.1 - 2.2e-23 82.5 27.9 9.9e-21 73.8 12.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_3 PF07969.6 EMR64235.1 - 1.1e-08 34.6 0.2 6.1e-05 22.4 0.0 2.9 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 EMR64235.1 - 1.1e-06 28.8 0.0 1.1e-05 25.6 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EMR64235.1 - 4.5e-05 23.1 0.0 0.00014 21.5 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase MFS_2 PF13347.1 EMR64235.1 - 0.00042 18.8 3.4 0.00042 18.8 2.4 2.9 2 2 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 EMR64235.1 - 0.0018 16.5 2.4 0.0028 15.9 1.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) A_deaminase PF00962.17 EMR64235.1 - 0.029 13.3 0.0 0.056 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase Alpha-L-AF_C PF06964.7 EMR64236.1 - 5.8e-32 110.8 0.0 1.1e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CorA PF01544.13 EMR64237.1 - 0.00012 21.2 1.3 0.00029 19.9 0.9 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Pkinase PF00069.20 EMR64238.1 - 2.4e-70 236.6 0.0 2.7e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64238.1 - 2.9e-37 128.1 0.0 3.6e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR64238.1 - 2.5e-08 33.2 0.0 3.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HD PF01966.17 EMR64239.1 - 0.00018 21.5 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 HD domain Lectin_leg-like PF03388.8 EMR64240.1 - 2.4e-65 219.8 0.0 3.2e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EMR64240.1 - 0.0048 16.2 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain PBP1_TM PF14812.1 EMR64240.1 - 0.098 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal KA1 PF02149.14 EMR64241.1 - 1.8e-17 62.5 0.1 2.9e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Ribos_L4_asso_C PF14374.1 EMR64241.1 - 0.0037 17.1 0.0 0.0089 15.8 0.0 1.7 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain BAT2_N PF07001.6 EMR64242.1 - 0.064 13.5 5.7 0.081 13.2 4.0 1.1 1 0 0 1 1 1 0 BAT2 N-terminus Asr PF06392.6 EMR64242.1 - 7.9 6.9 9.5 5.9 7.3 4.7 2.0 2 0 0 2 2 2 0 Acid shock protein repeat adh_short PF00106.20 EMR64243.1 - 4.6e-31 107.9 0.5 6.6e-31 107.4 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR64243.1 - 4.1e-29 102.0 0.1 5.4e-29 101.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR64243.1 - 6.5e-13 48.7 0.1 1e-12 48.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR64243.1 - 1.6e-05 24.4 0.1 5.6e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.17 EMR64243.1 - 3.3e-05 23.5 0.3 0.00023 20.8 0.1 2.2 2 0 0 2 2 2 1 PA domain Polysacc_synt_2 PF02719.10 EMR64243.1 - 0.019 13.8 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMR64243.1 - 0.045 12.4 0.0 0.063 11.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2493 PF10686.4 EMR64243.1 - 0.11 12.0 0.1 2.3 7.8 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2493) Patatin PF01734.17 EMR64244.1 - 2.4e-08 34.1 0.0 4.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4_2 PF13923.1 EMR64244.1 - 0.069 13.1 5.7 0.18 11.8 3.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMR64244.1 - 0.2 11.3 3.7 0.4 10.3 2.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rcd1 PF04078.8 EMR64245.1 - 7.2e-131 434.7 4.2 9.8e-131 434.3 2.9 1.2 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like OSCP PF00213.13 EMR64245.1 - 0.33 10.8 3.5 2 8.2 0.0 2.9 3 2 0 3 3 3 0 ATP synthase delta (OSCP) subunit BAF1_ABF1 PF04684.8 EMR64245.1 - 0.77 8.5 7.2 1.2 7.9 5.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor V-ATPase_H_N PF03224.9 EMR64245.1 - 1.1 8.3 7.0 7.2 5.6 2.8 2.8 1 1 0 1 1 1 0 V-ATPase subunit H Pkinase PF00069.20 EMR64246.1 - 5.4e-49 166.6 0.0 2e-28 99.2 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64246.1 - 2.3e-30 105.5 0.4 2.6e-15 56.2 0.0 2.4 2 1 1 3 3 3 2 Protein tyrosine kinase Borrelia_P83 PF05262.6 EMR64247.1 - 2.6 6.2 10.9 1.9 6.6 1.7 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein PHD PF00628.24 EMR64248.1 - 3.9e-12 45.6 7.5 3.9e-12 45.6 5.2 2.3 2 0 0 2 2 2 1 PHD-finger Macoilin PF09726.4 EMR64248.1 - 0.00034 19.0 3.3 0.00034 19.0 2.3 1.2 1 0 0 1 1 1 1 Transmembrane protein TATR PF03430.8 EMR64248.1 - 2.1 6.8 7.6 3 6.3 5.2 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Mucin PF01456.12 EMR64248.1 - 2.5 7.8 16.1 5.5 6.7 11.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein SCO1-SenC PF02630.9 EMR64249.1 - 1e-59 201.0 0.0 1.4e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EMR64249.1 - 5.4e-06 26.0 0.0 1e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EMR64249.1 - 0.00045 20.2 0.0 0.00082 19.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EMR64249.1 - 0.0083 15.6 0.0 0.16 11.5 0.0 2.3 1 1 0 1 1 1 1 Redoxin BCA_ABC_TP_C PF12399.3 EMR64249.1 - 0.031 13.9 0.2 0.26 11.0 0.1 2.3 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter SCIMP PF15050.1 EMR64250.1 - 0.013 15.3 0.0 0.013 15.3 0.0 2.9 2 1 1 3 3 3 0 SCIMP protein Choline_kinase PF01633.15 EMR64251.1 - 5.2e-60 202.6 0.0 1.3e-59 201.3 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EMR64251.1 - 1.4e-22 78.9 0.0 2.5e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EMR64251.1 - 8.7e-07 28.9 0.2 1.8e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Hydrolase_like PF13242.1 EMR64252.1 - 1.4e-18 66.3 0.2 1.5e-17 63.0 0.1 2.7 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EMR64252.1 - 1.4e-16 60.2 0.0 2.9e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMR64252.1 - 4.2e-06 27.0 0.0 0.0059 16.8 0.0 3.2 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR64252.1 - 5.1e-05 23.7 0.0 0.54 10.6 0.0 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Peptidase_M35 PF02102.10 EMR64253.1 - 7.1e-92 307.8 18.3 7.8e-92 307.6 12.7 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EMR64253.1 - 2.5e-06 28.0 0.6 4.5e-06 27.2 0.4 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase CARDB PF07705.6 EMR64253.1 - 0.093 12.7 0.1 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 CARDB Potyvirid-P3 PF13608.1 EMR64253.1 - 0.13 11.3 0.4 0.18 10.9 0.3 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein DUF3433 PF11915.3 EMR64254.1 - 2.6e-26 91.6 0.4 2.6e-26 91.6 0.3 4.2 5 0 0 5 5 5 3 Protein of unknown function (DUF3433) DFP PF04127.10 EMR64255.1 - 2.6e-14 53.2 0.0 1.4e-05 24.7 0.0 3.4 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein DUF4557 PF15101.1 EMR64255.1 - 0.023 14.5 1.4 0.041 13.7 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF702 PF05142.7 EMR64255.1 - 0.24 11.5 4.2 3.1 7.9 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) WSC PF01822.14 EMR64256.1 - 6.5e-12 45.2 5.1 2.4e-11 43.4 3.5 2.1 1 0 0 1 1 1 1 WSC domain ORC6 PF05460.8 EMR64256.1 - 0.14 11.2 2.7 0.3 10.1 1.9 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SKG6 PF08693.5 EMR64256.1 - 1.6 8.1 4.4 6.3 6.1 3.0 2.1 1 1 0 1 1 1 0 Transmembrane alpha-helix domain GATA PF00320.22 EMR64257.1 - 8.1e-17 60.2 1.9 1.6e-16 59.3 1.3 1.5 1 0 0 1 1 1 1 GATA zinc finger Peptidase_S28 PF05577.7 EMR64258.1 - 2.2e-41 141.8 4.4 7.8e-40 136.7 0.4 2.5 1 1 1 2 2 2 2 Serine carboxypeptidase S28 Pkinase PF00069.20 EMR64259.1 - 8.6e-59 198.7 0.2 1.1e-38 132.9 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64259.1 - 4.1e-28 98.1 0.6 4.5e-20 71.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EMR64259.1 - 3.2e-06 27.5 0.2 1.2e-05 25.7 0.2 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMR64259.1 - 0.0014 17.6 0.0 0.0064 15.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMR64259.1 - 0.0092 15.7 0.3 0.27 10.9 0.0 2.9 1 1 2 3 3 3 1 Phosphotransferase enzyme family FMN_dh PF01070.13 EMR64260.1 - 1.4e-109 366.2 0.0 3.4e-109 364.9 0.0 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EMR64260.1 - 2.6e-07 29.9 0.0 4.2e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EMR64260.1 - 3.1e-05 23.0 0.4 0.00018 20.5 0.2 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EMR64260.1 - 0.0026 16.9 0.3 0.004 16.3 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.16 EMR64260.1 - 0.055 12.4 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 EMR64260.1 - 0.083 12.1 0.0 0.41 9.8 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein CFEM PF05730.6 EMR64261.1 - 0.011 15.5 8.5 0.25 11.1 5.9 2.5 1 1 0 1 1 1 0 CFEM domain Pyrid_oxidase_2 PF13883.1 EMR64262.1 - 1.3e-44 151.9 0.0 2.2e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3716 PF12511.3 EMR64263.1 - 4.6e-10 38.9 0.7 8.7e-10 38.0 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) zf-RING_6 PF14835.1 EMR64263.1 - 0.33 10.7 8.8 0.33 10.7 4.4 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein adh_short PF00106.20 EMR64264.1 - 2.8e-18 66.3 0.6 6.7e-18 65.1 0.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR64264.1 - 7.4e-08 32.2 0.1 1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EMR64264.1 - 4.8e-05 22.5 0.5 6.6e-05 22.0 0.4 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase SIMPL PF04402.9 EMR64264.1 - 0.078 12.8 0.2 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF541) ApbA PF02558.11 EMR64265.1 - 2.9e-33 114.4 0.1 3.8e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EMR64265.1 - 4e-29 101.1 0.0 5.8e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal MFS_1 PF07690.11 EMR64266.1 - 2.3e-36 125.2 51.1 3.2e-29 101.7 20.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR64266.1 - 7.5e-08 31.1 10.6 7.5e-08 31.1 7.4 1.8 1 1 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.19 EMR64266.1 - 6.3e-05 21.7 20.1 7e-05 21.5 9.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EMR64266.1 - 0.14 11.9 4.9 0.071 12.9 0.4 2.4 2 0 0 2 2 2 0 MFS_1 like family MFS_1 PF07690.11 EMR64267.1 - 4.8e-38 130.7 41.5 1.8e-37 128.8 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR64267.1 - 1.6e-07 30.2 3.7 1.6e-07 30.2 2.6 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1752 PF08550.5 EMR64268.1 - 7.1e-11 41.4 2.8 7.1e-11 41.4 2.0 1.7 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) Wbp11 PF09429.5 EMR64269.1 - 2.3e-23 81.9 8.5 2.3e-23 81.9 5.9 2.0 2 0 0 2 2 2 1 WW domain binding protein 11 Lipoprotein_7 PF01540.11 EMR64269.1 - 0.0087 15.1 2.3 0.012 14.6 1.6 1.1 1 0 0 1 1 1 1 Adhesin lipoprotein DUF2294 PF10057.4 EMR64269.1 - 0.048 13.3 0.2 0.083 12.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) DUF3306 PF11748.3 EMR64269.1 - 0.92 10.1 10.3 4.2 8.0 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) MFS_1 PF07690.11 EMR64270.1 - 4e-33 114.5 30.6 4e-33 114.5 21.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_1 PF00561.15 EMR64271.1 - 0.00021 20.9 0.0 0.0038 16.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF3129 PF11327.3 EMR64272.1 - 3.8e-54 183.3 13.4 3.8e-54 183.3 9.3 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) I-set PF07679.11 EMR64272.1 - 0.072 12.9 0.1 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin I-set domain Stm1_N PF09598.5 EMR64273.1 - 3.3e-13 50.1 2.5 3.3e-13 50.1 1.7 4.4 3 2 1 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.10 EMR64273.1 - 2e-06 28.2 4.2 2e-06 28.2 2.9 3.3 4 1 0 4 4 4 1 Hyaluronan / mRNA binding family Peptidase_S10 PF00450.17 EMR64276.1 - 1.1e-93 314.6 0.2 1.5e-93 314.1 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_M20 PF01546.23 EMR64277.1 - 4.2e-22 78.5 0.1 7.2e-22 77.8 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMR64277.1 - 4.5e-07 29.5 0.0 9.8e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.11 EMR64278.1 - 7.7e-27 93.9 40.5 7.7e-27 93.9 28.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2721 PF11026.3 EMR64278.1 - 0.026 14.1 0.6 0.026 14.1 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) PA PF02225.17 EMR64279.1 - 1.1e-07 31.4 0.0 2.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 PA domain KNOX1 PF03790.8 EMR64280.1 - 0.11 11.7 0.1 0.32 10.3 0.1 1.7 1 0 0 1 1 1 0 KNOX1 domain DUF2396 PF09654.5 EMR64280.1 - 0.13 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) GMC_oxred_C PF05199.8 EMR64281.1 - 4.2e-32 111.4 0.0 7.2e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR64281.1 - 2.1e-29 102.6 0.0 3.6e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMR64281.1 - 0.00054 18.9 0.1 0.0013 17.6 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR64281.1 - 0.00096 18.0 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMR64281.1 - 0.0032 17.3 0.0 0.0047 16.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HHH PF00633.18 EMR64281.1 - 0.26 11.0 1.2 6.9 6.5 0.1 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif GMC_oxred_C PF05199.8 EMR64282.1 - 1.7e-35 122.3 0.0 2.3e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase CorA PF01544.13 EMR64283.1 - 6.5e-05 22.1 6.7 0.00075 18.6 4.6 2.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Chitin_synth_1 PF01644.12 EMR64284.1 - 1.1e-80 269.1 0.5 1.6e-80 268.6 0.3 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EMR64284.1 - 2.1e-33 113.8 0.0 3.8e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EMR64284.1 - 3.2e-23 81.9 2.1 1.3e-16 60.0 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EMR64284.1 - 4.8e-07 29.8 0.0 2.4e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EMR64284.1 - 5.7e-07 29.4 9.3 5.7e-07 29.4 6.5 3.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Prominin PF05478.6 EMR64284.1 - 0.013 13.0 0.0 0.022 12.3 0.0 1.3 1 0 0 1 1 1 0 Prominin SLAC1 PF03595.12 EMR64285.1 - 2.2e-64 217.1 42.0 2.5e-64 217.0 29.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Peptidase_M50 PF02163.17 EMR64285.1 - 0.022 13.7 0.3 0.35 9.7 0.0 2.8 1 1 1 2 2 2 0 Peptidase family M50 Adeno_E3 PF06040.6 EMR64285.1 - 0.024 14.5 1.3 3.8 7.4 0.1 2.7 3 0 0 3 3 3 0 Adenovirus E3 protein PulS_OutS PF09691.5 EMR64286.1 - 0.097 12.6 0.2 0.16 11.9 0.2 1.6 1 1 0 1 1 1 0 Bacterial chaperone lipoprotein (PulS_OutS) Pectate_lyase PF03211.8 EMR64287.1 - 4e-74 248.6 2.7 4.6e-74 248.4 1.9 1.0 1 0 0 1 1 1 1 Pectate lyase Actin PF00022.14 EMR64290.1 - 1.7e-131 438.3 0.0 1.9e-131 438.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMR64290.1 - 0.034 12.7 0.0 5.2 5.5 0.0 2.6 2 1 0 2 2 2 0 MreB/Mbl protein CorA PF01544.13 EMR64291.1 - 0.064 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Amidoligase_2 PF12224.3 EMR64292.1 - 1.2e-18 67.6 0.0 2.5e-14 53.5 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme zf-CCCH PF00642.19 EMR64294.1 - 0.0019 17.8 1.6 0.0033 17.0 1.1 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EMR64294.1 - 0.0021 17.9 4.3 0.0035 17.2 3.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type DUF4065 PF13274.1 EMR64294.1 - 3.3 8.4 6.1 0.69 10.6 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF4065) Myc_N PF01056.13 EMR64295.1 - 0.028 13.5 0.7 0.045 12.9 0.5 1.4 1 0 0 1 1 1 0 Myc amino-terminal region DUF572 PF04502.8 EMR64295.1 - 3.8 6.6 13.3 7.6 5.6 9.2 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF572) Fig1 PF12351.3 EMR64297.1 - 0.0023 17.8 7.5 0.0043 16.9 5.2 1.4 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 YtxH PF12732.2 EMR64297.1 - 0.024 15.0 0.1 5.4 7.4 0.1 2.8 2 1 0 2 2 2 0 YtxH-like protein Imm15 PF15590.1 EMR64297.1 - 0.082 11.9 0.1 0.19 10.8 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 15 Baculo_PEP_C PF04513.7 EMR64297.1 - 0.13 12.1 0.2 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MT0933_antitox PF14013.1 EMR64297.1 - 0.14 12.2 2.8 0.29 11.2 1.0 2.0 2 0 0 2 2 2 0 MT0933-like antitoxin protein Glyco_hydro_76 PF03663.9 EMR64298.1 - 1.3e-42 146.5 3.9 1.3e-42 146.5 2.7 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EMR64298.1 - 0.00025 20.1 0.3 0.0025 16.8 0.0 2.6 1 1 1 2 2 2 1 Glycosyl Hydrolase Family 88 DUF3602 PF12223.3 EMR64299.1 - 1.6e-14 54.0 13.7 4.1e-11 43.1 1.7 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) RtxA PF07634.6 EMR64299.1 - 2.4 8.6 8.5 1.2 9.6 0.1 3.3 3 1 0 3 3 3 0 RtxA repeat TPR_14 PF13428.1 EMR64300.1 - 2e-05 24.8 1.5 0.0019 18.6 0.1 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMR64300.1 - 3.2e-05 23.4 6.6 0.00091 18.9 0.5 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMR64300.1 - 4.4e-05 22.9 5.1 0.0017 18.0 0.2 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EMR64300.1 - 0.00029 20.9 2.4 0.0035 17.4 1.2 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EMR64300.1 - 0.00032 20.9 4.1 0.0092 16.3 2.6 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMR64300.1 - 0.0025 18.4 4.3 0.0063 17.1 0.1 3.4 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMR64300.1 - 0.0041 16.7 5.1 0.026 14.1 1.9 2.7 1 1 1 2 2 2 1 TPR repeat TPR_12 PF13424.1 EMR64300.1 - 0.0054 16.6 5.2 0.59 10.1 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMR64300.1 - 0.0066 16.8 4.2 0.029 14.8 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMR64300.1 - 0.014 15.2 1.7 0.13 12.1 0.1 2.7 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Adaptin_N PF01602.15 EMR64300.1 - 0.015 13.6 0.0 0.021 13.1 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region TPR_17 PF13431.1 EMR64300.1 - 0.029 14.5 0.2 16 6.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.5 EMR64300.1 - 0.031 13.3 0.5 0.045 12.8 0.3 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_7 PF13176.1 EMR64300.1 - 0.046 13.5 3.6 0.054 13.3 0.3 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 EMR64300.1 - 0.076 13.1 0.3 0.076 13.1 0.2 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 EMR64300.1 - 0.081 13.2 1.5 0.27 11.5 0.2 2.2 2 1 1 3 3 3 0 Bacterial transcriptional activator domain Glyco_hydro_92 PF07971.7 EMR64300.1 - 0.087 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 TPR_1 PF00515.23 EMR64300.1 - 0.1 12.2 1.2 1.4 8.6 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMR64300.1 - 0.14 12.1 2.0 4.6 7.3 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribonucleas_3_3 PF14622.1 EMR64301.1 - 0.00023 21.1 0.4 0.022 14.7 0.0 2.2 1 1 1 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EMR64301.1 - 0.0037 17.7 0.2 0.018 15.4 0.1 1.9 1 1 0 1 1 1 1 Ribonuclease III domain PemK PF02452.12 EMR64302.1 - 0.082 13.1 0.1 0.21 11.7 0.1 1.7 1 1 0 1 1 1 0 PemK-like protein Nop14 PF04147.7 EMR64302.1 - 0.74 7.6 2.9 0.96 7.2 2.0 1.0 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EMR64302.1 - 9.7 5.8 9.9 13 5.3 6.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_M36 PF02128.10 EMR64305.1 - 1.3e-124 415.9 5.1 2e-124 415.2 3.5 1.3 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EMR64305.1 - 2.6e-09 36.3 3.1 8.9e-09 34.6 1.7 2.2 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_MA_2 PF13485.1 EMR64305.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Flavoprotein PF02441.14 EMR64306.1 - 1.4e-26 92.6 0.4 9.5e-20 70.5 0.0 2.2 2 0 0 2 2 2 2 Flavoprotein DUF3720 PF12517.3 EMR64306.1 - 4.9 7.9 10.4 0.58 10.8 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) Sec1 PF00995.18 EMR64307.1 - 2.4e-105 353.3 0.0 7e-105 351.7 0.0 1.6 1 1 0 1 1 1 1 Sec1 family PhyH PF05721.8 EMR64309.1 - 3.4e-21 76.2 0.0 5.2e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pkinase PF00069.20 EMR64310.1 - 3.4e-12 46.0 0.1 1.9e-09 37.0 0.0 2.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64310.1 - 2.4e-07 30.0 0.0 8.1e-06 25.0 0.0 2.4 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMR64310.1 - 0.0022 17.7 0.1 1 9.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EMR64310.1 - 0.08 11.9 0.1 0.19 10.6 0.0 1.5 1 1 1 2 2 2 0 Fructosamine kinase PhyH PF05721.8 EMR64311.1 - 1.6e-29 103.4 0.1 2e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.11 EMR64312.1 - 2.5e-51 174.4 36.8 3.5e-51 173.9 25.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR64312.1 - 3.3e-07 29.2 20.3 3.3e-07 29.2 14.0 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter BSMAP PF12280.3 EMR64312.1 - 0.24 11.2 0.1 0.39 10.5 0.0 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein OATP PF03137.15 EMR64312.1 - 0.32 8.9 17.4 1.1 7.2 0.2 3.2 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.14 EMR64313.1 - 4.9e-13 48.8 0.8 3e-06 26.5 0.0 3.2 3 1 0 3 3 3 2 FAD binding domain DAO PF01266.19 EMR64313.1 - 5.6e-11 41.9 4.7 1.1e-06 27.7 0.1 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR64313.1 - 3e-09 36.2 0.1 6.4e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMR64313.1 - 7.1e-08 32.3 0.2 3e-07 30.3 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMR64313.1 - 3.7e-07 29.5 0.4 1.3e-06 27.7 0.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR64313.1 - 5.8e-07 28.3 0.0 2.7e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EMR64313.1 - 6.5e-06 25.2 0.1 0.0001 21.3 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EMR64313.1 - 7.8e-06 25.9 0.1 0.00011 22.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR64313.1 - 3.8e-05 22.7 0.1 0.15 10.9 0.1 2.5 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.22 EMR64313.1 - 6.8e-05 23.1 0.1 0.0032 17.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR64313.1 - 0.00017 21.6 0.1 0.00072 19.6 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMR64313.1 - 0.00061 18.5 0.3 0.083 11.5 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Amino_oxidase PF01593.19 EMR64313.1 - 0.001 18.2 0.7 1.6 7.7 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 EMR64313.1 - 0.0041 16.2 0.0 0.0095 15.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EMR64313.1 - 0.024 14.4 0.4 5 6.8 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EMR64313.1 - 0.049 12.9 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EMR64313.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EMR64313.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans_2 PF11951.3 EMR64314.1 - 6.5e-32 110.5 0.0 8.5e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain G_glu_transpept PF01019.16 EMR64315.1 - 5.9e-138 460.5 0.0 7e-138 460.2 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MFS_1 PF07690.11 EMR64318.1 - 7.9e-12 44.5 13.5 4.3e-07 28.9 0.1 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily UPF0118 PF01594.11 EMR64319.1 - 0.1 11.5 0.2 1.5 7.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF20 Filament PF00038.16 EMR64320.1 - 0.00058 19.4 8.0 0.00074 19.0 3.7 1.9 2 0 0 2 2 2 1 Intermediate filament protein HAUS6_N PF14661.1 EMR64320.1 - 0.0098 15.2 2.5 0.014 14.7 1.7 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus CCDC155 PF14662.1 EMR64320.1 - 0.017 14.7 4.4 0.036 13.6 3.0 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DASH_Spc34 PF08657.5 EMR64320.1 - 0.022 14.4 7.0 0.012 15.2 3.5 1.5 1 1 0 1 1 1 0 DASH complex subunit Spc34 Fib_alpha PF08702.5 EMR64320.1 - 0.072 13.2 5.8 0.16 12.1 2.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.6 EMR64320.1 - 0.094 12.1 6.4 2.4 7.6 0.7 2.7 1 1 2 3 3 3 0 Phage minor structural protein GP20 Atg14 PF10186.4 EMR64320.1 - 0.15 11.0 10.2 0.076 11.9 5.2 1.7 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FlxA PF14282.1 EMR64320.1 - 0.16 11.9 4.4 0.3 11.0 2.4 1.9 2 0 0 2 2 2 0 FlxA-like protein Kinesin-relat_1 PF12711.2 EMR64320.1 - 0.2 12.0 4.2 0.29 11.5 1.0 2.3 2 0 0 2 2 2 0 Kinesin motor FliD_C PF07195.7 EMR64320.1 - 0.32 10.2 4.7 1.5 8.0 3.3 2.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus V_ATPase_I PF01496.14 EMR64320.1 - 0.32 8.7 3.1 0.36 8.6 2.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spectrin PF00435.16 EMR64320.1 - 0.35 11.1 7.4 0.62 10.3 2.5 2.8 1 1 2 3 3 3 0 Spectrin repeat HALZ PF02183.13 EMR64320.1 - 0.37 10.5 7.9 0.42 10.3 3.3 2.7 2 1 0 2 2 2 0 Homeobox associated leucine zipper MbeD_MobD PF04899.7 EMR64320.1 - 0.41 10.5 4.6 3.9 7.4 0.7 2.6 1 1 1 2 2 2 0 MbeD/MobD like DWNN PF08783.6 EMR64320.1 - 0.46 10.4 4.9 4.2 7.3 0.1 2.9 1 1 1 3 3 3 0 DWNN domain TMPIT PF07851.8 EMR64320.1 - 0.46 9.4 2.4 0.78 8.7 1.6 1.4 1 1 0 1 1 1 0 TMPIT-like protein Sec8_exocyst PF04048.9 EMR64320.1 - 0.73 9.4 6.6 1.4 8.5 2.7 2.3 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF4200 PF13863.1 EMR64320.1 - 0.74 9.7 9.2 0.53 10.2 3.0 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) DUF3450 PF11932.3 EMR64320.1 - 0.91 8.7 7.0 1.9 7.6 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Phage_GPO PF05929.6 EMR64320.1 - 1.1 8.4 7.9 1 8.5 4.0 1.8 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Occludin_ELL PF07303.8 EMR64320.1 - 1.2 9.8 5.9 9.5 7.0 2.3 2.7 1 1 1 2 2 2 0 Occludin homology domain Cortex-I_coil PF09304.5 EMR64320.1 - 2.1 8.4 9.5 2.1 8.4 4.9 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil IncA PF04156.9 EMR64320.1 - 3.7 7.0 13.9 5.4 6.5 5.9 2.2 1 1 1 2 2 2 0 IncA protein Baculo_PEP_C PF04513.7 EMR64320.1 - 4.8 7.0 9.1 5.9 6.7 2.8 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C4H2 PF10146.4 EMR64320.1 - 6.6 6.6 7.4 7.4 6.5 3.0 1.9 1 1 1 2 2 2 0 Zinc finger-containing protein Wbp11 PF09429.5 EMR64320.1 - 9.7 6.2 8.9 1.1 9.2 1.0 2.7 2 1 1 3 3 3 0 WW domain binding protein 11 Glutaredoxin PF00462.19 EMR64321.1 - 1.4e-14 53.7 0.0 2.6e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin PRELI PF04707.9 EMR64322.1 - 2.7e-23 82.2 0.5 2.6e-20 72.5 0.1 2.1 2 0 0 2 2 2 2 PRELI-like family DUF2505 PF10698.4 EMR64322.1 - 0.094 12.2 0.2 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) Aldo_ket_red PF00248.16 EMR64323.1 - 1.2e-70 237.6 0.0 1.3e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Caps_synth PF05704.7 EMR64324.1 - 1.7e-09 37.3 0.0 3.9e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EMR64324.1 - 0.0012 19.1 0.1 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Fe-S_biosyn PF01521.15 EMR64325.1 - 4.5e-19 68.4 0.0 6e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis TFIIA PF03153.8 EMR64325.1 - 8.8 6.1 11.2 11 5.8 7.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aa_trans PF01490.13 EMR64326.1 - 4.2e-16 58.4 9.0 4.9e-16 58.2 6.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4282 PF14110.1 EMR64326.1 - 0.51 10.5 6.6 1.3 9.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) MFS_1 PF07690.11 EMR64327.1 - 3.1e-10 39.3 33.7 5.3e-07 28.6 9.4 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily GMC_oxred_C PF05199.8 EMR64328.1 - 3.7e-16 59.7 0.0 6.2e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR64328.1 - 0.00074 18.7 0.1 0.015 14.4 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EMR64328.1 - 0.0059 16.6 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR64328.1 - 0.016 15.1 0.0 0.044 13.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR64328.1 - 0.019 13.8 0.2 0.044 12.6 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR64328.1 - 0.021 13.6 0.0 0.039 12.8 0.0 1.4 2 0 0 2 2 2 0 FAD binding domain Aminotran_3 PF00202.16 EMR64329.1 - 3.8e-80 269.2 0.0 4.5e-80 269.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Fer2_2 PF01799.15 EMR64329.1 - 0.65 9.9 3.6 11 6.0 0.0 2.8 2 1 0 2 2 2 0 [2Fe-2S] binding domain DUF1741 PF08427.5 EMR64330.1 - 6.4e-86 287.6 0.0 1.5e-85 286.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) DUF3632 PF12311.3 EMR64331.1 - 5.5e-31 107.8 5.2 7.3e-31 107.3 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Serglycin PF04360.7 EMR64332.1 - 0.0019 17.9 0.5 0.0019 17.9 0.3 1.9 2 0 0 2 2 2 1 Serglycin Pkinase PF00069.20 EMR64333.1 - 5e-58 196.2 0.0 2.2e-57 194.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64333.1 - 6.2e-35 120.5 0.0 4.2e-33 114.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMR64333.1 - 2e-08 33.5 0.0 2.3e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EMR64333.1 - 0.00023 20.9 0.2 0.00049 19.9 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family p450 PF00067.17 EMR64334.1 - 1.3e-08 33.8 0.0 6.3e-08 31.5 0.0 1.8 1 1 1 2 2 2 1 Cytochrome P450 OPT PF03169.10 EMR64335.1 - 1.8e-28 99.4 0.0 2.2e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GCN5L1 PF06320.8 EMR64336.1 - 2.6e-06 27.2 0.1 4.7e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Serglycin PF04360.7 EMR64336.1 - 0.2 11.4 7.4 0.57 9.9 5.1 1.9 1 1 0 1 1 1 0 Serglycin PAT1 PF09770.4 EMR64336.1 - 1.5 6.9 24.8 2.5 6.2 17.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Steroid_dh PF02544.11 EMR64337.1 - 4e-29 101.3 1.7 6.7e-29 100.6 1.2 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EMR64337.1 - 0.011 15.8 0.3 0.011 15.8 0.2 2.3 3 0 0 3 3 3 0 Phospholipid methyltransferase DUF1295 PF06966.7 EMR64337.1 - 0.069 12.4 0.3 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) p450 PF00067.17 EMR64338.1 - 8.7e-35 120.1 0.0 9.4e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trypsin PF00089.21 EMR64339.1 - 2.8e-10 40.1 0.0 4.9e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EMR64339.1 - 2e-08 34.2 0.0 4.1e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Sec5 PF15469.1 EMR64339.1 - 0.081 12.6 0.2 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 Imm29 PF15575.1 EMR64339.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 29 4HBT_3 PF13622.1 EMR64340.1 - 1.7e-33 116.4 2.3 1.9e-33 116.2 1.6 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily ATP-synt_DE_N PF02823.11 EMR64340.1 - 0.07 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain HET PF06985.6 EMR64341.1 - 1e-10 41.9 0.1 4.3e-07 30.1 0.0 2.8 3 0 0 3 3 3 2 Heterokaryon incompatibility protein (HET) CinA PF02464.12 EMR64342.1 - 1.7e-34 118.4 2.1 1.9e-34 118.3 1.5 1.0 1 0 0 1 1 1 1 Competence-damaged protein FSH1 PF03959.8 EMR64343.1 - 4e-16 59.1 0.0 5.5e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.6 EMR64343.1 - 0.076 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain PGP_phosphatase PF09419.5 EMR64344.1 - 5e-36 123.5 0.0 6.2e-36 123.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EMR64344.1 - 1.5e-05 24.6 0.0 1.9e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 HAD-hyrolase-like DUF2092 PF09865.4 EMR64344.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) p450 PF00067.17 EMR64345.1 - 1.1e-39 136.3 0.1 5.6e-24 84.4 0.0 2.8 2 1 0 2 2 2 2 Cytochrome P450 FAD_binding_3 PF01494.14 EMR64345.1 - 1e-11 44.5 0.6 3.1e-05 23.2 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR64345.1 - 0.00097 18.1 0.4 0.027 13.3 0.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR64345.1 - 0.0073 16.3 0.1 0.021 14.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMR64345.1 - 0.009 14.9 0.2 0.017 14.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMR64345.1 - 0.073 11.5 0.1 0.12 10.8 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EMR64345.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR64345.1 - 0.14 12.0 0.1 0.46 10.3 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CVNH PF08881.5 EMR64346.1 - 7.2e-31 106.4 0.2 8e-31 106.3 0.2 1.0 1 0 0 1 1 1 1 CVNH domain Gly-zipper_OmpA PF13436.1 EMR64347.1 - 0.099 12.3 1.9 0.39 10.3 1.3 1.8 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain ArgJ PF01960.13 EMR64348.1 - 2.3e-139 464.1 0.2 3.3e-139 463.5 0.1 1.2 1 0 0 1 1 1 1 ArgJ family Rep_fac_C PF08542.6 EMR64348.1 - 4.4e-18 65.0 0.0 9.7e-18 63.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EMR64348.1 - 1.1e-10 41.8 0.0 2.4e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EMR64348.1 - 1.5e-10 41.0 0.0 5.3e-09 35.9 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EMR64348.1 - 1.1e-06 28.5 0.0 2.4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR64348.1 - 1.2e-05 25.3 0.0 0.00053 20.0 0.0 3.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMR64348.1 - 0.0001 22.4 0.1 0.017 15.2 0.1 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMR64348.1 - 0.00011 21.3 0.0 0.00029 19.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 EMR64348.1 - 0.00043 19.8 0.0 0.00085 18.8 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EMR64348.1 - 0.001 18.6 0.0 0.0029 17.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EMR64348.1 - 0.0017 17.8 0.0 0.15 11.4 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain AAA_19 PF13245.1 EMR64348.1 - 0.0034 17.0 0.0 0.022 14.4 0.0 2.4 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EMR64348.1 - 0.011 14.8 0.0 0.05 12.7 0.0 1.9 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 EMR64348.1 - 0.022 13.4 0.0 0.66 8.5 0.0 2.5 2 1 1 3 3 3 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 EMR64348.1 - 0.042 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_31 PF13614.1 EMR64348.1 - 0.05 13.5 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EMR64348.1 - 0.052 13.0 0.1 0.45 9.9 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase DNA_pol3_delta PF06144.8 EMR64348.1 - 0.053 13.0 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_25 PF13481.1 EMR64348.1 - 0.053 12.9 0.1 0.27 10.6 0.0 2.2 1 1 1 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EMR64348.1 - 0.064 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.9 EMR64348.1 - 0.089 12.5 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EMR64348.1 - 0.089 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EMR64348.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 EMR64348.1 - 0.16 12.2 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain KR PF08659.5 EMR64351.1 - 2.9e-46 157.4 0.3 2.5e-27 95.7 0.1 2.8 1 1 1 2 2 2 2 KR domain adh_short PF00106.20 EMR64351.1 - 1.8e-34 119.0 0.3 1e-18 67.8 0.1 2.7 1 1 1 2 2 2 2 short chain dehydrogenase PS-DH PF14765.1 EMR64351.1 - 8.9e-29 100.5 0.0 1.4e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 EMR64351.1 - 2.6e-19 69.0 0.0 5.6e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR64351.1 - 1.1e-13 52.1 0.0 4.8e-13 50.1 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR64351.1 - 5.1e-07 29.4 0.4 1.3e-06 28.1 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_12 PF08242.7 EMR64351.1 - 1.4e-06 28.6 0.0 3.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR64351.1 - 7.7e-06 26.0 0.0 2.2e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site RrnaAD PF00398.15 EMR64351.1 - 0.094 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 EMR64351.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMR64351.1 - 0.12 12.7 0.0 0.46 10.8 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.12 EMR64351.1 - 0.14 11.5 0.0 0.45 9.8 0.0 1.8 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Rax2 PF12768.2 EMR64352.1 - 0.055 12.6 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Methyltransf_2 PF00891.13 EMR64353.1 - 3.5e-25 88.6 0.0 6.5e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase HTH_IclR PF09339.5 EMR64353.1 - 0.029 13.9 0.1 0.065 12.8 0.1 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain MFS_1 PF07690.11 EMR64354.1 - 0.014 14.1 0.6 0.017 13.8 0.4 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily CAP59_mtransfer PF11735.3 EMR64355.1 - 0.031 13.4 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 GFA PF04828.9 EMR64356.1 - 1.4e-05 24.9 1.4 1.4e-05 24.9 1.0 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Myticin-prepro PF10690.4 EMR64356.1 - 1.7 8.7 6.0 0.44 10.5 2.0 1.6 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel CutC PF03932.9 EMR64357.1 - 3.6e-29 101.4 1.7 2.1e-15 56.5 0.1 3.5 3 1 0 3 3 3 3 CutC family His_biosynth PF00977.16 EMR64357.1 - 0.068 12.4 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein TIM PF00121.13 EMR64357.1 - 0.083 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Triosephosphate isomerase DER1 PF04511.10 EMR64358.1 - 2.1e-12 46.9 0.6 2.5e-12 46.7 0.4 1.0 1 0 0 1 1 1 1 Der1-like family SSPI PF14098.1 EMR64358.1 - 0.033 14.1 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Small, acid-soluble spore protein I DUF1689 PF07954.6 EMR64358.1 - 0.082 12.7 0.1 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) ORC2 PF04084.9 EMR64359.1 - 4e-94 315.1 0.0 4.9e-94 314.8 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 MS_channel PF00924.13 EMR64360.1 - 2.3e-20 72.8 1.3 4.3e-20 71.9 0.9 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.1 EMR64360.1 - 0.0041 16.8 0.0 1.1 9.3 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EMR64360.1 - 0.036 13.3 0.4 0.098 12.0 0.2 1.8 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 EMR64360.1 - 0.085 13.0 0.3 0.46 10.6 0.0 2.2 2 1 1 3 3 3 0 EF-hand domain pair FAD_binding_4 PF01565.18 EMR64361.1 - 1.2e-17 63.6 1.4 2.8e-17 62.4 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR64361.1 - 1.5e-06 27.9 0.4 3.7e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like NmrA PF05368.8 EMR64362.1 - 3.2e-34 118.2 0.0 3.9e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR64362.1 - 5.3e-14 52.6 0.7 6.6e-14 52.3 0.5 1.1 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMR64362.1 - 0.0001 22.2 1.2 0.0002 21.3 0.4 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR64362.1 - 0.00016 21.3 0.5 0.00049 19.8 0.1 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EMR64362.1 - 0.00022 20.7 0.2 0.0004 19.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3798 PF12683.2 EMR64362.1 - 0.00044 19.4 0.1 0.00079 18.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3798) 3Beta_HSD PF01073.14 EMR64362.1 - 0.002 16.9 0.1 0.0036 16.0 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMR64362.1 - 0.021 13.7 0.0 0.087 11.7 0.1 2.0 2 1 0 2 2 2 0 Male sterility protein Saccharop_dh PF03435.13 EMR64362.1 - 0.067 12.1 0.2 0.094 11.6 0.2 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase AnfO_nitrog PF09582.5 EMR64364.1 - 0.75 8.8 5.1 0.17 10.9 0.4 2.1 3 0 0 3 3 3 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) PI-PLC-X PF00388.14 EMR64365.1 - 6.8e-56 187.7 0.0 1.3e-55 186.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EMR64365.1 - 3.5e-39 133.4 0.1 1.1e-38 131.8 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EMR64365.1 - 3e-07 30.2 0.2 3.8e-06 26.6 0.0 2.6 2 0 0 2 2 2 1 C2 domain PH PF00169.24 EMR64365.1 - 0.00037 20.6 1.0 0.00075 19.6 0.1 2.0 2 0 0 2 2 2 1 PH domain Mcp5_PH PF12814.2 EMR64365.1 - 0.0017 18.3 0.1 0.0042 16.9 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology EF-hand_like PF09279.6 EMR64365.1 - 0.0059 16.5 0.2 0.17 11.9 0.0 2.8 1 1 1 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.27 EMR64365.1 - 0.0062 15.7 0.0 0.03 13.6 0.0 2.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EMR64365.1 - 0.014 15.5 0.1 0.11 12.7 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 EMR64365.1 - 0.015 15.1 0.7 0.072 13.0 0.1 2.6 3 0 0 3 3 3 0 EF-hand domain TrmE_N PF10396.4 EMR64366.1 - 8.5e-21 74.0 0.0 2.8e-20 72.4 0.0 1.9 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EMR64366.1 - 3.4e-16 59.3 1.5 2.5e-15 56.6 0.0 2.9 2 1 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EMR64366.1 - 7.6e-16 58.1 0.1 2.1e-15 56.6 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMR64366.1 - 3.1e-05 23.3 0.0 6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EMR64366.1 - 3.2e-05 23.7 0.0 5.6e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Dynamin family Miro PF08477.8 EMR64366.1 - 0.0011 19.4 0.0 0.0025 18.2 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EMR64366.1 - 0.0031 16.7 0.0 0.0073 15.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EMR64366.1 - 0.0039 16.6 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 EMR64366.1 - 0.021 14.7 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMR64366.1 - 0.027 14.7 0.0 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter NMO PF03060.10 EMR64367.1 - 1.6e-68 231.2 7.3 2e-68 230.9 5.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EMR64367.1 - 8.8e-07 28.1 1.6 1.1e-05 24.5 1.1 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EMR64367.1 - 0.00034 19.5 9.5 0.0006 18.7 6.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EMR64367.1 - 0.38 9.6 6.8 0.61 8.9 4.7 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase UQ_con PF00179.21 EMR64368.1 - 6.1e-50 168.2 0.0 6.9e-50 168.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pmp3 PF01679.12 EMR64369.1 - 4.4e-20 71.1 8.3 5.5e-20 70.7 5.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Ribosomal_L28e PF01778.12 EMR64370.1 - 7.8e-35 119.8 3.1 1.8e-34 118.5 1.2 2.1 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EMR64370.1 - 1.5e-20 73.1 42.0 2.5e-17 62.7 23.4 3.4 2 1 0 2 2 2 1 Mak16 protein C-terminal region Methyltransf_11 PF08241.7 EMR64371.1 - 0.016 15.6 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EMR64371.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family BCS1_N PF08740.6 EMR64372.1 - 8.6e-28 97.2 0.0 1.6e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EMR64372.1 - 3.2e-19 69.4 0.0 2.6e-10 40.5 0.0 2.6 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMR64372.1 - 0.00048 20.9 0.0 0.0019 18.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EMR64372.1 - 0.00096 18.6 0.0 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMR64372.1 - 0.008 15.9 0.1 0.026 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EMR64372.1 - 0.0082 16.4 0.0 0.021 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMR64372.1 - 0.015 14.3 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 EMR64372.1 - 0.019 14.1 0.0 0.061 12.4 0.0 1.8 1 1 0 1 1 1 0 KaiC AAA_28 PF13521.1 EMR64372.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EMR64372.1 - 0.022 13.4 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_11 PF13086.1 EMR64372.1 - 0.024 14.2 0.0 0.054 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMR64372.1 - 0.035 13.8 0.0 0.25 11.0 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 EMR64372.1 - 0.04 13.4 0.4 0.11 12.1 0.3 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMR64372.1 - 0.048 13.8 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EMR64372.1 - 0.097 12.0 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EMR64372.1 - 0.1 12.5 0.1 0.45 10.4 0.0 2.3 1 1 0 1 1 1 0 AAA ATPase domain IPT PF01745.11 EMR64372.1 - 0.14 11.2 0.0 0.33 10.0 0.0 1.6 2 0 0 2 2 2 0 Isopentenyl transferase Polyoma_lg_T_C PF06431.6 EMR64372.1 - 1.1 7.8 4.1 18 3.8 0.0 2.2 1 1 1 2 2 2 0 Polyomavirus large T antigen C-terminus zf-DHHC PF01529.15 EMR64374.1 - 2.6e-40 137.6 10.8 4e-40 137.0 7.5 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DZR PF12773.2 EMR64374.1 - 0.081 12.7 6.1 0.15 11.9 4.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon YfhO PF09586.5 EMR64374.1 - 3.8 5.3 6.3 0.17 9.8 0.3 1.6 2 0 0 2 2 2 0 Bacterial membrane protein YfhO adh_short PF00106.20 EMR64375.1 - 2.3e-16 60.1 0.0 5.6e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EMR64375.1 - 0.0038 16.6 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EMR64375.1 - 0.014 15.0 0.1 0.072 12.7 0.1 2.2 1 1 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.3 EMR64375.1 - 0.019 14.7 0.9 0.042 13.6 0.3 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UQ_con PF00179.21 EMR64376.1 - 1.1e-21 76.6 0.0 1.6e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EMR64376.1 - 0.033 14.0 0.2 0.08 12.8 0.0 1.7 2 0 0 2 2 2 0 RWD domain Prok-E2_B PF14461.1 EMR64376.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B MCM PF00493.18 EMR64377.1 - 2.9e-143 476.6 0.1 4.3e-143 476.0 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMR64377.1 - 2.7e-18 66.6 1.0 1.4e-17 64.2 0.3 2.4 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMR64377.1 - 6.9e-07 28.6 0.0 0.0002 20.6 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMR64377.1 - 3.6e-05 23.5 0.0 7.6e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EMR64377.1 - 0.00036 20.1 0.0 0.0018 17.9 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EMR64377.1 - 0.019 15.1 0.9 0.38 10.9 0.0 3.2 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMR64377.1 - 0.035 13.5 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Lon_2 PF13337.1 EMR64377.1 - 0.046 12.0 0.2 0.91 7.7 0.0 2.1 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease Mg_chelatase_2 PF13335.1 EMR64377.1 - 0.1 12.9 0.6 0.27 11.6 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI F-box-like PF12937.2 EMR64378.1 - 0.00084 19.0 0.2 0.0018 17.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMR64378.1 - 0.013 15.1 0.2 0.03 13.9 0.1 1.6 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.2 EMR64378.1 - 0.12 12.0 0.0 61 3.3 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) FAD_binding_3 PF01494.14 EMR64379.1 - 4e-09 36.0 7.6 0.0005 19.2 2.6 3.6 3 1 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EMR64379.1 - 0.0017 18.3 1.3 0.0066 16.4 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMR64379.1 - 0.0041 16.9 0.2 0.0092 15.7 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding p450 PF00067.17 EMR64380.1 - 7.3e-33 113.7 0.4 2.8e-32 111.8 0.3 1.8 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EMR64381.1 - 7.5e-19 68.2 2.8 2e-18 66.9 1.9 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR64381.1 - 5.9e-09 35.8 0.2 7.2e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR64381.1 - 7.6e-08 32.4 0.0 1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR64381.1 - 9.4e-08 31.7 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR64381.1 - 2.8e-05 24.2 0.6 3.8e-05 23.7 0.4 1.4 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR64381.1 - 0.099 11.8 0.3 0.14 11.3 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family S_layer_C PF05124.7 EMR64382.1 - 0.01 15.5 1.4 0.016 14.8 1.0 1.3 1 0 0 1 1 1 1 S-layer like family, C-terminal region Vps54 PF07928.7 EMR64383.1 - 3.4e-46 156.7 0.2 1.5e-45 154.6 0.0 1.9 2 0 0 2 2 2 1 Vps54-like protein DUF3150 PF11348.3 EMR64383.1 - 0.019 14.0 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) DUF4398 PF14346.1 EMR64384.1 - 0.051 13.6 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DUF1996 PF09362.5 EMR64385.1 - 7.5e-82 274.5 2.8 9e-82 274.2 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) zf-C2H2 PF00096.21 EMR64386.1 - 2e-12 46.6 16.8 0.013 15.8 0.7 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR64386.1 - 9.1e-11 41.3 12.2 0.012 15.9 0.2 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMR64386.1 - 6e-10 38.9 9.4 0.014 15.5 0.7 5.4 4 1 1 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMR64386.1 - 3.2e-09 36.6 10.9 0.051 13.7 0.2 5.4 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EMR64386.1 - 1.2e-07 31.7 18.9 3.7e-05 23.7 1.2 3.5 2 1 1 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EMR64386.1 - 5.8e-06 26.3 17.7 0.37 10.9 0.6 4.4 2 2 1 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EMR64386.1 - 6.6e-05 23.0 19.0 1.1 9.6 0.5 5.6 5 0 0 5 5 5 2 Zinc-finger double domain FdhE PF04216.7 EMR64386.1 - 0.00039 20.2 0.8 0.0013 18.5 0.2 2.0 2 0 0 2 2 2 1 Protein involved in formate dehydrogenase formation zinc_ribbon_5 PF13719.1 EMR64386.1 - 0.013 15.0 20.9 1.3 8.6 0.0 5.4 4 1 1 5 5 5 0 zinc-ribbon domain Prok-RING_1 PF14446.1 EMR64386.1 - 0.03 14.0 10.1 9.5 6.0 0.3 4.9 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 zinc_ribbon_4 PF13717.1 EMR64386.1 - 0.031 13.9 22.3 1.4 8.6 0.0 5.4 4 1 1 5 5 5 0 zinc-ribbon domain RRN7 PF11781.3 EMR64386.1 - 0.12 11.8 3.4 16 5.1 0.1 3.5 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Med25_NR-box PF11244.3 EMR64386.1 - 0.24 11.8 3.0 0.68 10.4 2.1 1.8 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing TerY-C PF15616.1 EMR64386.1 - 0.24 11.3 0.1 0.24 11.3 0.1 2.7 3 0 0 3 3 3 0 TerY-C metal binding domain zf-DNA_Pol PF08996.5 EMR64386.1 - 0.38 10.0 10.6 2.8 7.2 0.8 2.8 2 1 1 3 3 3 0 DNA Polymerase alpha zinc finger DUF2225 PF09986.4 EMR64386.1 - 0.48 9.8 12.3 3.2 7.1 1.2 3.9 4 1 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_6 PF13912.1 EMR64386.1 - 0.87 9.5 18.9 2.2 8.2 0.1 5.7 6 0 0 6 6 6 0 C2H2-type zinc finger IBR PF01485.16 EMR64386.1 - 0.92 9.4 11.4 2.1 8.2 0.4 3.5 3 1 0 3 3 3 0 IBR domain zf-RING_2 PF13639.1 EMR64386.1 - 2.7 7.9 14.1 10 6.0 2.3 3.8 3 1 0 3 3 3 0 Ring finger domain DZR PF12773.2 EMR64386.1 - 2.7 7.8 10.9 13 5.7 2.6 3.2 2 1 0 2 2 2 0 Double zinc ribbon PHD PF00628.24 EMR64386.1 - 2.9 7.6 8.9 17 5.1 0.4 3.5 3 0 0 3 3 3 0 PHD-finger OrfB_Zn_ribbon PF07282.6 EMR64386.1 - 5.2 6.7 10.7 0.64 9.7 0.4 3.4 3 1 0 3 3 3 0 Putative transposase DNA-binding domain LIM PF00412.17 EMR64386.1 - 6 7.0 9.0 4.2 7.5 1.6 3.1 2 2 0 2 2 2 0 LIM domain Cys_rich_KTR PF14205.1 EMR64386.1 - 6.7 6.2 6.9 21 4.6 0.1 3.2 3 0 0 3 3 3 0 Cysteine-rich KTR C1_4 PF07975.7 EMR64386.1 - 8.6 6.4 16.2 57 3.8 0.4 4.0 2 2 1 3 3 3 0 TFIIH C1-like domain DUF4407 PF14362.1 EMR64387.1 - 4.3 6.1 7.5 5.3 5.9 5.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gloverin PF10793.4 EMR64388.1 - 0.98 9.0 9.3 4.4 6.9 4.6 2.5 1 1 1 2 2 2 0 Gloverin-like protein FARP PF01581.11 EMR64388.1 - 5.5 7.7 10.6 66 4.5 0.4 4.2 4 0 0 4 4 4 0 FMRFamide related peptide family DUF2293 PF10056.4 EMR64389.1 - 1.3e-24 85.9 2.6 1.3e-24 85.9 1.8 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) FAD_binding_1 PF00667.15 EMR64390.1 - 1.3e-43 148.9 0.0 2.1e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EMR64390.1 - 1.6e-09 38.3 0.0 3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain BBE PF08031.7 EMR64391.1 - 4.2e-11 42.5 0.4 7.2e-11 41.8 0.3 1.4 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EMR64391.1 - 4.2e-09 36.0 1.6 9e-09 34.9 1.1 1.6 1 0 0 1 1 1 1 FAD binding domain DUF2129 PF09902.4 EMR64391.1 - 0.022 14.5 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) Cytokin-bind PF09265.5 EMR64391.1 - 0.056 12.5 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.18 EMR64393.1 - 1.4e-29 102.2 0.2 2.6e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DUF4185 PF13810.1 EMR64397.1 - 4.4e-05 22.5 0.0 5.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Pkinase PF00069.20 EMR64398.1 - 2e-07 30.4 0.0 0.0095 15.1 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64398.1 - 0.00093 18.3 0.0 0.017 14.2 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase SDA1 PF05285.7 EMR64399.1 - 0.032 13.5 11.2 0.044 13.0 7.7 1.2 1 0 0 1 1 1 0 SDA1 Polyketide_cyc2 PF10604.4 EMR64400.1 - 6.7e-16 58.7 0.1 7.5e-16 58.5 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ADH_N PF08240.7 EMR64401.1 - 4.2e-09 36.1 0.0 2.3e-08 33.7 0.0 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR64401.1 - 2.1e-08 33.7 0.0 3.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.20 EMR64406.1 - 6.6e-32 110.6 2.3 9.8e-25 87.1 0.2 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64406.1 - 1.7e-12 46.9 0.6 6.2e-11 41.8 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 EMR64406.1 - 0.11 11.8 0.1 0.25 10.6 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Zip PF02535.17 EMR64408.1 - 0.35 9.8 3.0 0.56 9.1 2.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Med26 PF08711.6 EMR64409.1 - 1.1e-12 47.2 0.1 2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Fungal_trans PF04082.13 EMR64410.1 - 5.3e-19 68.0 0.2 8e-19 67.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EMR64411.1 - 1.3e-13 51.2 0.0 1.9e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR64411.1 - 3.1e-07 30.2 0.0 4.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR64411.1 - 0.0021 17.8 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Brr6_like_C_C PF10104.4 EMR64412.1 - 8.8e-28 96.4 0.2 1.4e-27 95.8 0.1 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain GP41 PF00517.12 EMR64412.1 - 0.24 10.9 0.0 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 Retroviral envelope protein APC_CDC26 PF10471.4 EMR64412.1 - 1.2 9.9 13.2 0.29 11.8 5.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 p450 PF00067.17 EMR64413.1 - 7.6e-55 186.2 0.0 1.1e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3336 PF11815.3 EMR64414.1 - 5.2e-48 162.2 1.6 8e-48 161.6 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EMR64414.1 - 5.9e-19 68.8 0.2 1e-13 51.6 0.2 2.7 2 1 1 3 3 3 2 Patatin-like phospholipase Smoothelin PF12510.3 EMR64414.1 - 0.046 13.5 0.3 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein dsDNA_bind PF01984.15 EMR64414.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Double-stranded DNA-binding domain DEAD PF00270.24 EMR64416.1 - 5.6e-41 139.8 0.4 1.4e-40 138.5 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR64416.1 - 4.1e-29 100.2 0.2 9.1e-29 99.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 EMR64416.1 - 0.017 14.7 0.8 0.039 13.5 0.5 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMR64416.1 - 0.019 14.6 0.2 0.048 13.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 EMR64416.1 - 0.027 14.2 0.1 0.076 12.8 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EMR64416.1 - 0.045 13.4 0.3 0.15 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 EMR64416.1 - 0.11 12.6 1.0 0.49 10.5 0.7 2.0 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 EMR64416.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Helicase Amino_oxidase PF01593.19 EMR64418.1 - 2.1e-10 40.3 0.0 2.8e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMR64418.1 - 7.7e-09 35.4 0.0 1.9e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMR64418.1 - 0.00099 18.2 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EMR64418.1 - 0.0015 17.4 0.1 0.0024 16.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR64418.1 - 0.0035 17.4 0.0 0.0066 16.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR64418.1 - 0.006 15.4 0.0 0.0073 15.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EMR64418.1 - 0.019 14.0 0.1 0.029 13.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Rrp15p PF07890.7 EMR64419.1 - 1.6e-32 112.2 3.8 1.6e-32 112.2 2.6 2.7 2 1 0 2 2 2 1 Rrp15p CAF1A PF12253.3 EMR64419.1 - 0.88 9.7 14.8 0.091 12.8 0.7 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A CENP-B_dimeris PF09026.5 EMR64419.1 - 6.6 7.0 14.9 0.56 10.4 3.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Macoilin PF09726.4 EMR64419.1 - 7.1 4.7 20.1 9.7 4.3 13.9 1.1 1 0 0 1 1 1 0 Transmembrane protein K_trans PF02705.11 EMR64420.1 - 6.2e-156 519.8 1.8 7.5e-156 519.6 1.3 1.1 1 0 0 1 1 1 1 K+ potassium transporter Macoilin PF09726.4 EMR64421.1 - 0.016 13.5 5.5 0.017 13.4 3.8 1.2 1 0 0 1 1 1 0 Transmembrane protein RNA12 PF10443.4 EMR64421.1 - 0.021 13.3 1.0 0.024 13.1 0.7 1.1 1 0 0 1 1 1 0 RNA12 protein Gon7 PF08738.5 EMR64421.1 - 0.47 10.4 3.3 1.1 9.2 1.5 2.0 2 0 0 2 2 2 0 Gon7 family TipAS PF07739.8 EMR64421.1 - 0.7 10.2 6.1 4.6 7.5 4.2 2.0 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain Mito_carr PF00153.22 EMR64422.1 - 2.2e-14 52.9 0.0 7.7e-05 22.3 0.1 4.2 3 1 1 4 4 4 4 Mitochondrial carrier protein Glyco_hydro_47 PF01532.15 EMR64423.1 - 8.2e-164 545.5 0.0 9.5e-164 545.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Fer2 PF00111.22 EMR64424.1 - 2.6e-12 46.3 0.6 3.4e-12 45.9 0.4 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 EMR64426.1 - 8e-61 201.7 5.4 4.8e-20 71.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3449 PF11931.3 EMR64427.1 - 3.6e-70 235.5 0.2 9.4e-69 230.8 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3449) zf-met PF12874.2 EMR64427.1 - 2.6e-09 36.9 3.0 1.4e-07 31.4 0.6 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMR64427.1 - 6e-09 35.8 3.9 4.2e-08 33.0 1.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding SF3a60_bindingd PF12108.3 EMR64427.1 - 6.3e-09 35.2 0.0 1.3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_2 PF12756.2 EMR64427.1 - 0.00016 21.7 0.6 0.0038 17.2 0.1 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 EMR64427.1 - 0.0022 17.6 1.1 0.0022 17.6 0.8 2.2 2 1 0 2 2 2 1 DBF zinc finger DUF951 PF06107.6 EMR64427.1 - 0.054 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) Myb_CC_LHEQLE PF14379.1 EMR64427.1 - 0.12 11.9 3.4 0.45 10.1 2.3 2.0 1 1 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif zf-C2H2_4 PF13894.1 EMR64427.1 - 0.69 10.3 2.7 17 6.0 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger C1_2 PF03107.11 EMR64427.1 - 2.6 8.2 4.2 4.2 7.5 0.5 2.4 2 0 0 2 2 2 0 C1 domain PLU-1 PF08429.6 EMR64428.1 - 2.3e-102 342.3 13.9 9.6e-100 333.7 10.1 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EMR64428.1 - 7.8e-43 145.3 0.4 1.8e-42 144.1 0.3 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.11 EMR64428.1 - 2.1e-13 50.0 8.1 4.6e-13 49.0 5.6 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 EMR64428.1 - 3.6e-08 32.9 8.9 3.6e-08 32.9 6.2 4.1 3 1 0 3 3 3 1 PHD-finger Amino_oxidase PF01593.19 EMR64429.1 - 5.2e-28 98.3 0.4 6e-28 98.1 0.3 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Fungal_trans PF04082.13 EMR64433.1 - 2.7e-16 59.2 0.9 2.7e-16 59.2 0.6 2.6 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR64433.1 - 3.9e-08 33.0 9.6 7.7e-08 32.1 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 EMR64435.1 - 6.6e-14 52.0 0.0 1.8e-05 24.9 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMR64435.1 - 4.4e-07 29.5 0.2 0.058 13.6 0.0 5.7 5 1 1 6 6 6 1 Ankyrin repeat Ank PF00023.25 EMR64435.1 - 4.1e-06 26.3 0.5 0.31 10.9 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeat F-box-like PF12937.2 EMR64435.1 - 0.00049 19.7 0.0 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like Ank_4 PF13637.1 EMR64435.1 - 0.032 14.7 1.1 2.1 8.9 0.0 4.1 5 2 0 5 5 5 0 Ankyrin repeats (many copies) DUF515 PF04415.7 EMR64435.1 - 0.2 9.8 0.0 0.36 9.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF515) TauD PF02668.11 EMR64437.1 - 2.2e-52 178.2 0.1 2.8e-52 177.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EMR64437.1 - 0.012 14.5 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 CsiD DUF971 PF06155.7 EMR64437.1 - 0.013 15.9 0.0 0.04 14.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF971) ADH_zinc_N PF00107.21 EMR64438.1 - 1.6e-05 24.4 0.6 9.3e-05 21.9 0.4 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NAD_synthase PF02540.12 EMR64438.1 - 0.0027 16.6 0.1 1.5 7.6 0.0 2.1 2 0 0 2 2 2 2 NAD synthase Eno-Rase_NADH_b PF12242.3 EMR64438.1 - 0.1 12.3 0.3 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N_2 PF13602.1 EMR64438.1 - 0.13 13.1 0.0 0.32 11.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase IBR PF01485.16 EMR64439.1 - 1.2e-12 47.4 21.0 3.6e-08 33.1 2.8 4.1 4 0 0 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 EMR64439.1 - 4.9e-05 23.2 6.8 4.9e-05 23.2 4.7 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 EMR64439.1 - 5.2e-05 23.1 0.0 0.0029 17.5 0.0 3.5 4 0 0 4 4 4 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 EMR64439.1 - 0.00083 19.1 8.2 0.00083 19.1 5.7 4.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMR64439.1 - 0.0014 18.2 8.1 0.0014 18.2 5.6 4.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMR64439.1 - 0.0018 18.1 6.7 0.0018 18.1 4.7 3.6 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EMR64439.1 - 0.0041 16.8 8.5 0.0041 16.8 5.9 3.4 3 0 0 3 3 3 1 zinc-RING finger domain RRM_1 PF00076.17 EMR64439.1 - 0.023 14.3 0.0 0.47 10.1 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SLS PF14611.1 EMR64439.1 - 0.028 13.8 0.5 0.99 8.7 0.0 2.9 2 1 1 3 3 3 0 Mitochondrial inner-membrane-bound regulator RcsC PF09456.5 EMR64440.1 - 0.19 11.4 0.7 2.9 7.6 0.0 2.8 3 0 0 3 3 3 0 RcsC Alpha-Beta-Loop (ABL) MFS_1 PF07690.11 EMR64441.1 - 3.6e-26 91.7 25.3 1.2e-24 86.7 17.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EMR64442.1 - 6.7e-13 47.9 0.3 4.1e-06 25.6 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR64442.1 - 5.6e-05 22.9 10.1 5.6e-05 22.9 7.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Utp13 PF08625.6 EMR64443.1 - 7.5e-44 148.8 0.4 1e-43 148.3 0.3 1.2 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.27 EMR64443.1 - 1.6e-36 122.8 8.8 5.1e-07 29.3 0.0 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat Utp12 PF04003.7 EMR64443.1 - 0.032 14.1 0.4 0.056 13.3 0.2 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family Nucleoporin_N PF08801.6 EMR64443.1 - 0.092 11.4 0.2 2.4 6.7 0.0 3.0 4 0 0 4 4 4 0 Nup133 N terminal like Dehydratase_hem PF13816.1 EMR64444.1 - 1.5e-98 329.7 0.0 2e-98 329.2 0.0 1.2 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 EMR64444.1 - 0.00059 19.9 0.0 0.61 10.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) AA_permease_2 PF13520.1 EMR64445.1 - 7.7e-48 163.0 57.4 9.5e-48 162.7 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMR64445.1 - 2e-29 102.2 53.8 2.5e-29 101.9 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.3 EMR64445.1 - 0.15 11.7 0.5 0.33 10.6 0.4 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) DUF2592 PF10766.4 EMR64445.1 - 2.3 7.6 10.2 0.18 11.1 1.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2592) MBOAT_2 PF13813.1 EMR64446.1 - 2.7e-15 56.1 3.2 6.4e-15 55.0 2.2 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family XPG_I PF00867.13 EMR64447.1 - 5.1e-18 64.9 0.0 9e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EMR64447.1 - 0.00055 20.1 0.0 0.0024 18.1 0.0 2.1 1 1 0 1 1 1 1 XPG N-terminal domain Bax1-I PF01027.15 EMR64448.1 - 0.013 15.0 2.9 0.019 14.5 2.0 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 CopD PF05425.8 EMR64448.1 - 0.017 15.3 1.6 0.049 13.8 1.1 1.7 1 1 1 2 2 2 0 Copper resistance protein D P12 PF12669.2 EMR64448.1 - 0.046 13.9 0.2 0.046 13.9 0.1 1.7 2 0 0 2 2 2 0 Virus attachment protein p12 family PMT_2 PF13231.1 EMR64448.1 - 0.49 10.2 6.4 0.7 9.7 4.4 1.2 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase RseC_MucC PF04246.7 EMR64448.1 - 1 8.9 6.7 21 4.6 4.7 2.1 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Lipase_GDSL_2 PF13472.1 EMR64449.1 - 1.1e-08 35.4 0.2 1.3e-08 35.1 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMR64449.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.11 EMR64450.1 - 1.9e-14 53.1 16.1 1.9e-14 53.1 11.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMR64450.1 - 0.00057 19.4 0.8 0.002 17.6 0.6 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Chol_subst-bind PF09129.6 EMR64450.1 - 0.062 12.4 0.2 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding DUF2365 PF10157.4 EMR64451.1 - 4.5e-05 23.3 0.7 5.7e-05 23.0 0.5 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) HSBP1 PF06825.7 EMR64451.1 - 0.018 14.6 3.4 0.69 9.5 0.2 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 PLU-1 PF08429.6 EMR64451.1 - 0.025 13.4 0.8 0.033 13.0 0.6 1.2 1 0 0 1 1 1 0 PLU-1-like protein DUF3450 PF11932.3 EMR64451.1 - 0.047 12.9 7.4 0.099 11.8 4.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DASH_Dad2 PF08654.5 EMR64451.1 - 0.052 13.5 1.0 0.71 9.9 0.3 2.3 1 1 2 3 3 3 0 DASH complex subunit Dad2 Occludin_ELL PF07303.8 EMR64451.1 - 0.19 12.5 3.0 3.8 8.3 0.6 2.3 1 1 0 1 1 1 0 Occludin homology domain Retrotrans_gag PF03732.12 EMR64451.1 - 0.22 11.6 2.6 0.46 10.5 0.1 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein DUF4164 PF13747.1 EMR64451.1 - 0.33 11.1 4.2 6.7 6.9 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) FliJ PF02050.11 EMR64451.1 - 0.43 10.6 11.8 0.43 10.6 2.9 2.6 1 1 1 3 3 3 0 Flagellar FliJ protein CENP-F_leu_zip PF10473.4 EMR64451.1 - 0.59 9.9 4.2 3.3 7.5 0.1 2.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EMR64451.1 - 0.79 9.2 10.1 1.1 8.8 7.0 1.2 1 0 0 1 1 1 0 IncA protein PspB PF06667.7 EMR64451.1 - 1.9 8.5 6.3 0.91 9.4 0.4 2.5 2 1 0 2 2 2 0 Phage shock protein B V-SNARE PF05008.10 EMR64451.1 - 2.9 8.0 7.5 2.4 8.3 2.6 2.7 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Tup_N PF08581.5 EMR64451.1 - 7.9 6.7 10.1 3.3 7.9 5.2 1.8 2 1 0 2 2 2 0 Tup N-terminal Lipase_GDSL_2 PF13472.1 EMR64452.1 - 1.3e-09 38.4 0.1 4.7e-09 36.6 0.1 1.9 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMR64452.1 - 5.2e-08 33.0 4.0 4.4e-07 29.9 2.7 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EMR64452.1 - 0.0057 16.4 0.0 2.6 7.7 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Med4 PF10018.4 EMR64453.1 - 0.01 15.2 4.3 0.66 9.3 0.4 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Lebercilin PF15619.1 EMR64453.1 - 0.027 13.8 11.5 0.64 9.4 0.7 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4238 PF14022.1 EMR64453.1 - 0.044 13.0 1.7 0.052 12.8 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Spc7 PF08317.6 EMR64453.1 - 0.091 11.4 9.2 0.12 11.0 6.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2968 PF11180.3 EMR64453.1 - 0.13 11.6 5.8 0.17 11.2 3.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Atg14 PF10186.4 EMR64453.1 - 0.23 10.3 7.4 0.3 9.9 5.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 EMR64453.1 - 0.27 11.1 8.0 0.46 10.3 5.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 EMR64453.1 - 0.49 10.4 12.6 0.026 14.5 3.0 2.0 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF641 PF04859.7 EMR64453.1 - 0.51 10.0 5.8 0.48 10.1 1.7 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) IncA PF04156.9 EMR64453.1 - 0.69 9.4 13.8 1.3 8.5 9.6 1.5 1 1 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EMR64453.1 - 3.8 5.2 6.3 4.8 4.9 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 EMR64453.1 - 7.5 6.4 12.1 94 2.9 6.6 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding AKAP7_NLS PF10469.4 EMR64455.1 - 8.7e-27 94.1 0.0 1.9e-26 93.0 0.0 1.5 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 EMR64455.1 - 0.00046 19.9 0.0 0.0007 19.3 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily FHA PF00498.21 EMR64456.1 - 1.6e-15 56.9 0.0 2.8e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain DUF2410 PF10307.4 EMR64457.1 - 6.5e-78 260.6 0.0 9.1e-78 260.1 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) DUF3104 PF11302.3 EMR64457.1 - 0.043 13.2 0.2 0.043 13.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) Glyco_hydro_18 PF00704.23 EMR64458.1 - 1.7e-72 244.7 0.1 1.6e-68 231.6 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Tim17 PF02466.14 EMR64459.1 - 3.1e-13 49.8 7.3 4.1e-13 49.4 5.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TraT PF05818.7 EMR64459.1 - 0.13 11.7 2.7 0.19 11.1 1.5 1.5 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein adh_short PF00106.20 EMR64462.1 - 3.6e-21 75.7 2.0 1.3e-20 73.9 1.4 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR64462.1 - 7.2e-09 35.5 0.5 5.3e-08 32.7 0.1 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EMR64462.1 - 2e-06 27.3 0.4 3.7e-06 26.5 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR64462.1 - 3.3e-06 27.2 0.4 5.4e-06 26.5 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EMR64462.1 - 6.8e-05 22.7 0.0 0.0026 17.5 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EMR64462.1 - 0.00039 19.7 0.3 0.00061 19.1 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.15 EMR64462.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HK97-gp10_like PF04883.7 EMR64462.1 - 0.014 16.3 0.0 0.038 14.9 0.0 1.7 2 0 0 2 2 1 0 Bacteriophage HK97-gp10, putative tail-component 3Beta_HSD PF01073.14 EMR64462.1 - 0.016 13.9 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EMR64462.1 - 0.039 13.9 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.12 EMR64462.1 - 0.049 12.5 0.0 0.081 11.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_transf_9 PF01075.12 EMR64462.1 - 0.052 12.7 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Methyltransf_26 PF13659.1 EMR64462.1 - 0.085 12.8 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.13 EMR64462.1 - 0.12 11.9 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Transferase PF02458.10 EMR64464.1 - 1.1e-07 30.7 0.0 0.069 11.5 0.0 3.0 2 1 1 3 3 3 3 Transferase family DUF167 PF02594.11 EMR64465.1 - 2.2e-19 69.1 0.1 3.2e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Tautomerase PF01361.16 EMR64465.1 - 0.1 12.2 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Tautomerase enzyme ADH_zinc_N PF00107.21 EMR64466.1 - 1.4e-31 108.7 0.1 2.3e-31 108.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR64466.1 - 3.8e-18 66.6 0.0 8.9e-18 65.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR64466.1 - 1.8e-10 40.5 0.1 9.4e-10 38.2 0.1 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NB-ARC PF00931.17 EMR64467.1 - 1.4e-07 30.6 0.0 1.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Peptidase_C15 PF01470.12 EMR64468.1 - 2.4e-14 53.6 0.0 1.9e-11 44.2 0.0 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase DNA_primase_S PF01896.14 EMR64469.1 - 3.3e-54 182.6 0.0 5.4e-54 181.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit PRCC PF10253.4 EMR64469.1 - 4.7 7.8 10.2 3.1 8.4 4.9 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting UCH PF00443.24 EMR64470.1 - 5.1e-36 124.1 0.0 9.2e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMR64470.1 - 3.4e-15 56.2 0.0 8.1e-10 38.6 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 EMR64470.1 - 0.00035 20.2 0.0 0.0015 18.2 0.0 2.1 1 0 0 1 1 1 1 PUB domain Flavin_Reduct PF01613.13 EMR64471.1 - 1.5e-17 63.8 6.3 4.6e-16 59.0 0.2 2.6 2 1 0 2 2 2 2 Flavin reductase like domain Mito_fiss_reg PF05308.6 EMR64471.1 - 1.4 8.1 6.1 0.63 9.3 1.9 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator Flavodoxin_1 PF00258.20 EMR64473.1 - 9.7e-23 80.7 0.0 2.4e-22 79.4 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.15 EMR64473.1 - 1.3e-09 37.8 0.0 1.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_5 PF12724.2 EMR64473.1 - 0.00043 20.3 0.0 0.00084 19.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_NdrI PF07972.6 EMR64473.1 - 0.003 17.4 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 NrdI Flavodoxin like p450 PF00067.17 EMR64473.1 - 0.0091 14.5 0.1 0.013 14.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_A21 PF03566.8 EMR64473.1 - 0.054 11.5 0.3 0.085 10.9 0.2 1.2 1 0 0 1 1 1 0 Peptidase family A21 Pkinase PF00069.20 EMR64475.1 - 3.3e-48 164.0 0.0 4e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64475.1 - 1.9e-25 89.3 0.0 2.6e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR64475.1 - 0.023 13.6 0.0 0.54 9.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EMR64475.1 - 0.024 14.3 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Med11 PF10280.4 EMR64477.1 - 3.2e-25 88.4 0.0 3.9e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein DUF3829 PF12889.2 EMR64477.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF3574 PF12098.3 EMR64478.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) FAD_binding_3 PF01494.14 EMR64479.1 - 6.6e-26 91.1 0.0 1.6e-25 89.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR64479.1 - 2.5e-10 39.8 0.3 0.00025 20.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR64479.1 - 9e-06 25.6 0.0 2.6e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMR64479.1 - 4e-05 23.9 0.7 0.0025 18.1 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EMR64479.1 - 8.8e-05 22.1 0.0 0.00021 20.9 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 EMR64479.1 - 0.00024 21.2 0.0 0.00072 19.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR64479.1 - 0.0012 17.7 0.1 0.0026 16.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EMR64479.1 - 0.0015 17.5 0.0 0.0038 16.2 0.0 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EMR64479.1 - 0.0028 16.8 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EMR64479.1 - 0.0029 16.7 0.0 0.0069 15.5 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMR64479.1 - 0.0032 16.1 0.1 0.092 11.3 0.0 2.7 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EMR64479.1 - 0.0052 16.6 0.2 0.03 14.2 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR64479.1 - 0.0099 14.3 0.0 0.16 10.4 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.5 EMR64479.1 - 0.016 14.0 0.0 0.055 12.2 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Amino_oxidase PF01593.19 EMR64479.1 - 0.02 14.0 0.0 0.25 10.3 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.17 EMR64479.1 - 0.044 12.6 0.1 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A CLP_protease PF00574.18 EMR64480.1 - 2.6e-63 212.9 0.1 1.2e-62 210.7 0.1 1.7 1 1 0 1 1 1 1 Clp protease SDH_sah PF01972.11 EMR64480.1 - 0.011 14.5 0.2 0.02 13.7 0.1 1.5 1 1 1 2 2 2 0 Serine dehydrogenase proteinase Cep57_CLD_2 PF14197.1 EMR64480.1 - 0.044 13.7 0.2 0.064 13.2 0.2 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 UDPGT PF00201.13 EMR64481.1 - 4.8e-05 22.1 0.0 7.1e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Vps5 PF09325.5 EMR64482.1 - 3.3e-87 291.6 6.3 5.3e-87 290.9 4.3 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EMR64482.1 - 2.3e-24 85.3 0.1 5.3e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR PF03114.13 EMR64482.1 - 0.0001 21.9 5.2 0.00016 21.2 3.6 1.2 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EMR64482.1 - 0.00076 18.4 1.8 0.0032 16.4 1.5 1.8 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3_WASP_bdg PF10456.4 EMR64482.1 - 0.0061 15.8 1.1 0.068 12.4 0.6 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PEP-utilisers_N PF05524.8 EMR64482.1 - 0.45 10.3 5.6 0.34 10.7 0.5 3.0 2 2 0 2 2 2 0 PEP-utilising enzyme, N-terminal KR PF08659.5 EMR64483.1 - 8e-59 198.3 4.5 3.3e-58 196.3 0.1 3.2 4 0 0 4 4 4 1 KR domain adh_short PF00106.20 EMR64483.1 - 3.1e-46 157.3 5.0 1.1e-44 152.3 0.1 3.0 3 0 0 3 3 3 2 short chain dehydrogenase PS-DH PF14765.1 EMR64483.1 - 4.4e-25 88.4 0.0 1.1e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 EMR64483.1 - 2.1e-20 73.0 0.0 2.9e-19 69.3 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain ADH_zinc_N PF00107.21 EMR64483.1 - 2.5e-18 65.8 0.2 1.7e-17 63.1 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR64483.1 - 1.5e-15 58.2 0.0 1.7e-14 54.8 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EMR64483.1 - 4.8e-14 52.3 0.0 1.5e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR64483.1 - 1e-08 35.5 0.0 1.5e-07 31.7 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR64483.1 - 1.5e-07 31.1 0.0 4.3e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR64483.1 - 4.2e-07 30.5 0.0 2.2e-06 28.2 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR64483.1 - 1.2e-06 27.8 0.0 4.1e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EMR64483.1 - 9.6e-05 22.5 0.8 0.00036 20.7 0.1 2.4 3 0 0 3 3 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 EMR64483.1 - 0.0014 18.9 0.0 0.011 16.0 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain WD40 PF00400.27 EMR64484.1 - 9.7e-52 171.1 26.9 9.6e-13 47.4 2.2 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EMR64484.1 - 4.2e-39 133.8 0.0 6.2e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 EMR64484.1 - 5.7e-06 25.8 0.0 1.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 EMR64484.1 - 5e-05 23.0 0.0 0.0011 18.7 0.0 2.6 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EMR64484.1 - 0.074 11.1 3.0 4.5 5.2 0.1 3.4 3 1 0 4 4 4 0 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.1 EMR64484.1 - 0.13 11.2 0.0 0.28 10.1 0.0 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Orbi_VP6 PF01516.11 EMR64484.1 - 4.9 6.1 11.7 9.4 5.1 8.1 1.4 1 0 0 1 1 1 0 Orbivirus helicase VP6 HSP90 PF00183.13 EMR64485.1 - 3.1e-256 850.8 32.5 3.7e-256 850.6 22.6 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EMR64485.1 - 2.6e-11 43.2 0.0 4.8e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMR64485.1 - 4e-11 42.7 0.2 4e-11 42.7 0.1 2.7 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 EMR64485.1 - 0.087 12.6 1.0 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 Tumour suppressor protein PVL_ORF50 PF07768.6 EMR64485.1 - 1 9.3 13.1 0.24 11.3 4.4 2.7 2 0 0 2 2 2 0 PVL ORF-50-like family Peptidase_S10 PF00450.17 EMR64485.1 - 1.5 7.9 5.3 1 8.4 0.0 2.3 1 1 0 2 2 2 0 Serine carboxypeptidase Tet_JBP PF12851.2 EMR64486.1 - 3e-08 33.1 0.0 5.9e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily FMO-like PF00743.14 EMR64487.1 - 0.0062 14.7 0.0 0.0091 14.2 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Lipase_3 PF01764.20 EMR64488.1 - 2.4e-35 121.2 0.0 3.9e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 EMR64488.1 - 1.2e-05 24.9 0.5 3e-05 23.7 0.3 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region DUF676 PF05057.9 EMR64488.1 - 3e-05 23.4 0.0 4.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EMR64488.1 - 0.0065 16.2 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR64488.1 - 0.0079 16.0 0.1 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Msg2_C PF12373.3 EMR64488.1 - 0.07 12.3 3.3 0.18 11.0 0.3 2.6 2 0 0 2 2 2 0 Major surface glycoprotein 2 C terminal PGAP1 PF07819.8 EMR64488.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Cutinase PF01083.17 EMR64488.1 - 0.14 11.8 4.0 0.055 13.1 0.2 2.3 2 1 0 2 2 2 0 Cutinase NUDIX PF00293.23 EMR64489.1 - 1.8e-10 40.5 0.1 3e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain DUF932 PF06067.6 EMR64489.1 - 0.063 12.5 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Mito_morph_reg PF14972.1 EMR64489.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator Abhydrolase_6 PF12697.2 EMR64490.1 - 1e-27 97.5 2.3 1.4e-27 97.0 1.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR64490.1 - 8.3e-11 41.8 0.2 9.2e-10 38.4 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR64490.1 - 7.2e-10 38.7 0.8 1.6e-09 37.6 0.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMR64490.1 - 0.00041 20.1 0.0 0.00088 19.0 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Glyco_hydro_43 PF04616.9 EMR64491.1 - 2e-26 92.7 0.6 2.4e-26 92.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Rad52_Rad22 PF04098.10 EMR64492.1 - 6.3e-62 207.8 0.0 7.6e-62 207.6 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Filament PF00038.16 EMR64493.1 - 1.2e-05 24.9 21.0 1.2e-05 24.9 14.6 3.9 2 1 0 3 3 3 2 Intermediate filament protein Vfa1 PF08432.5 EMR64493.1 - 0.012 15.6 18.4 0.012 15.6 12.7 4.7 3 1 1 4 4 4 0 AAA-ATPase Vps4-associated protein 1 Reo_sigmaC PF04582.7 EMR64493.1 - 0.46 9.6 10.1 0.84 8.7 0.3 2.4 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Shugoshin_N PF07558.6 EMR64493.1 - 5.2 6.8 15.7 12 5.6 0.1 5.4 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region NPV_P10 PF05531.7 EMR64493.1 - 9 6.6 9.2 7.7 6.8 0.1 4.3 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Lipase_GDSL_2 PF13472.1 EMR64494.1 - 1.3e-10 41.7 3.0 1.9e-10 41.1 2.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMR64494.1 - 1.8e-09 37.8 1.1 2.4e-09 37.3 0.7 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pkinase PF00069.20 EMR64495.1 - 3.4e-60 203.3 0.0 4.4e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64495.1 - 1.3e-38 132.5 0.0 1.7e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR64495.1 - 9.4e-06 24.7 0.0 2.1e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EMR64495.1 - 0.04 12.7 0.0 0.065 12.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 EMR64495.1 - 0.083 12.4 0.0 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Hydrolase PF00702.21 EMR64496.1 - 5.1e-08 33.5 0.2 6.4e-06 26.7 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMR64496.1 - 1.1e-07 32.1 0.0 0.00032 20.9 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR64496.1 - 2.2e-07 30.5 1.5 4e-07 29.6 0.8 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like Cu-oxidase_2 PF07731.9 EMR64497.1 - 2.8e-39 133.7 8.6 1e-35 122.2 0.5 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EMR64497.1 - 5.9e-37 126.0 7.2 2.6e-35 120.6 0.1 3.8 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EMR64497.1 - 2.7e-28 98.8 1.3 2.3e-25 89.3 0.1 2.8 2 1 1 3 3 3 2 Multicopper oxidase Acyl_transf_1 PF00698.16 EMR64499.1 - 7.4e-50 170.0 0.0 1.5e-49 169.0 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EMR64499.1 - 2.6e-49 168.0 0.1 4.6e-49 167.1 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thioesterase PF00975.15 EMR64499.1 - 2.4e-42 145.7 0.0 1.2e-41 143.4 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 EMR64499.1 - 3.6e-36 123.6 0.6 9.7e-36 122.2 0.4 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EMR64499.1 - 1.6e-21 76.2 2.5 1.9e-10 40.8 0.1 2.5 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EMR64499.1 - 5.5e-09 35.6 0.0 1.4e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 EMR64499.1 - 9.5e-08 32.1 0.4 0.00014 21.8 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR64499.1 - 3e-06 27.0 0.1 0.06 13.0 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EMR64499.1 - 9.9e-05 21.4 0.3 0.0005 19.1 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain DUF2974 PF11187.3 EMR64499.1 - 0.14 11.5 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SH2_2 PF14633.1 EMR64500.1 - 2.3e-83 278.6 0.1 2.3e-83 278.6 0.1 2.0 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 EMR64500.1 - 6e-38 129.4 4.4 6e-38 129.4 3.1 4.7 4 1 0 4 4 4 1 Death-like domain of SPT6 HHH_7 PF14635.1 EMR64500.1 - 1.4e-30 105.4 0.0 2.8e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EMR64500.1 - 1.7e-29 102.3 0.0 6.6e-29 100.4 0.0 2.1 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 EMR64500.1 - 4.8e-22 77.9 34.0 4.8e-22 77.9 23.6 6.4 5 1 1 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EMR64500.1 - 1.1e-19 70.5 1.8 2.6e-18 66.1 1.3 2.9 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 S1 PF00575.18 EMR64500.1 - 8.1e-07 29.0 0.5 3e-06 27.2 0.4 2.1 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.19 EMR64500.1 - 1e-05 25.2 0.0 4.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 SH2 domain HHH_3 PF12836.2 EMR64500.1 - 0.0048 16.8 0.0 0.024 14.5 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF3298 PF11738.3 EMR64500.1 - 0.072 13.6 0.1 0.72 10.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) adh_short_C2 PF13561.1 EMR64501.1 - 4.5e-10 39.7 0.0 5.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Oxysterol_BP PF01237.13 EMR64502.1 - 1.6e-100 336.0 0.0 1.8e-100 335.8 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein PAP1 PF08601.5 EMR64503.1 - 1e-40 140.5 3.5 1e-40 140.5 2.5 4.5 1 1 2 4 4 3 2 Transcription factor PAP1 bZIP_1 PF00170.16 EMR64503.1 - 1.4e-10 40.9 10.6 2.8e-10 39.9 7.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF904 PF06005.7 EMR64503.1 - 0.00049 20.3 4.3 0.0011 19.2 3.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF812 PF05667.6 EMR64503.1 - 0.0069 14.9 1.3 0.0097 14.4 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) IncA PF04156.9 EMR64503.1 - 0.007 15.9 4.0 0.03 13.9 3.2 1.6 2 0 0 2 2 2 1 IncA protein bZIP_2 PF07716.10 EMR64503.1 - 0.0073 16.0 15.5 0.048 13.4 10.8 2.3 1 1 0 1 1 1 1 Basic region leucine zipper IFP_35_N PF07334.8 EMR64503.1 - 0.0077 16.1 0.7 0.022 14.6 0.5 1.8 1 0 0 1 1 1 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus Adeno_PIX PF03955.9 EMR64503.1 - 0.015 15.8 0.5 0.015 15.8 0.4 1.7 2 0 0 2 2 1 0 Adenovirus hexon-associated protein (IX) CENP-H PF05837.7 EMR64503.1 - 0.015 15.4 3.6 0.03 14.4 2.5 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) dsrm PF00035.20 EMR64503.1 - 0.037 14.6 0.3 0.3 11.6 0.0 2.4 2 0 0 2 2 2 0 Double-stranded RNA binding motif ACCA PF03255.9 EMR64503.1 - 0.042 13.4 0.3 0.069 12.7 0.2 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF972 PF06156.8 EMR64503.1 - 0.048 13.9 1.1 0.11 12.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_Maf PF03131.12 EMR64503.1 - 0.071 13.4 9.3 0.13 12.5 6.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor FlaC_arch PF05377.6 EMR64503.1 - 0.096 12.5 2.3 0.18 11.7 1.6 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF603 PF04645.7 EMR64503.1 - 0.11 12.4 2.2 0.19 11.6 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF603 DivIC PF04977.10 EMR64503.1 - 0.16 11.4 4.0 0.29 10.6 2.8 1.5 1 0 0 1 1 1 0 Septum formation initiator TMF_DNA_bd PF12329.3 EMR64503.1 - 0.16 11.7 8.9 0.38 10.5 6.2 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Macoilin PF09726.4 EMR64503.1 - 0.31 9.2 7.0 0.43 8.7 4.9 1.2 1 0 0 1 1 1 0 Transmembrane protein GAS PF13851.1 EMR64503.1 - 0.34 10.0 9.1 0.59 9.2 6.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EMR64503.1 - 0.35 9.8 3.7 0.61 9.0 2.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin PF02996.12 EMR64503.1 - 0.42 10.2 4.1 0.76 9.4 2.8 1.4 1 0 0 1 1 1 0 Prefoldin subunit DUF641 PF04859.7 EMR64503.1 - 1.5 8.5 6.6 2.6 7.7 4.6 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Sigma70_ner PF04546.8 EMR64503.1 - 1.9 8.0 8.8 4.5 6.8 6.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Bap31 PF05529.7 EMR64503.1 - 6.6 6.1 7.4 12 5.3 5.1 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Tet_JBP PF12851.2 EMR64504.1 - 7.9e-06 25.2 0.0 1.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Glyco_hydro_31 PF01055.21 EMR64505.1 - 9.9e-110 367.3 0.1 1.2e-109 367.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMR64505.1 - 7.5e-16 57.7 1.3 4e-15 55.4 0.0 2.8 3 0 0 3 3 3 1 Galactose mutarotase-like Ceramidase_alk PF04734.8 EMR64506.1 - 1e-257 856.4 1.4 3.4e-256 851.4 0.9 2.0 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Utp14 PF04615.8 EMR64507.1 - 2.1e-169 565.1 70.8 2.1e-169 565.1 49.1 2.4 1 1 1 2 2 2 1 Utp14 protein Glucosamine_iso PF01182.15 EMR64508.1 - 9e-18 64.7 0.0 1.5e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NIR_SIR PF01077.17 EMR64510.1 - 6.8e-29 100.2 0.0 1.3e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 EMR64510.1 - 9.5e-27 94.1 0.2 1.8e-26 93.2 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR64510.1 - 4e-16 59.1 2.7 8.8e-14 51.6 0.6 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 EMR64510.1 - 1.3e-14 53.9 2.2 4.6e-12 45.8 2.3 2.8 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.1 EMR64510.1 - 7.7e-13 48.0 0.0 1.9e-05 24.3 0.0 2.6 2 0 0 2 2 2 2 Rieske-like [2Fe-2S] domain Rieske PF00355.21 EMR64510.1 - 2.2e-11 43.1 0.1 1e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 EMR64510.1 - 2.2e-09 36.7 0.0 4.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 EMR64510.1 - 6.5e-08 32.8 0.1 0.00072 19.6 0.0 3.3 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR64510.1 - 0.00042 20.1 1.0 3.4 7.4 0.0 3.9 2 2 2 4 4 4 2 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EMR64510.1 - 0.018 14.1 0.2 2.7 6.9 0.0 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 EMR64510.1 - 0.029 13.2 0.0 0.086 11.7 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Hexokinase_2 PF03727.11 EMR64511.1 - 1.9e-34 118.9 0.0 3.4e-27 95.2 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EMR64511.1 - 9.5e-32 109.9 0.0 1.4e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Abhydrolase_3 PF07859.8 EMR64512.1 - 2.4e-40 138.3 0.1 1.3e-31 109.8 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EMR64512.1 - 3.4e-16 58.8 0.0 7.8e-16 57.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EMR64512.1 - 1.6e-05 23.8 0.0 0.085 11.5 0.0 2.3 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 EMR64512.1 - 0.00031 20.5 0.0 0.00072 19.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR64512.1 - 0.001 19.0 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family BSD PF03909.12 EMR64513.1 - 9.2e-16 57.3 0.1 2.1e-15 56.1 0.1 1.7 1 0 0 1 1 1 1 BSD domain Suf PF05843.9 EMR64513.1 - 0.0067 16.1 1.5 0.0067 16.1 1.1 2.2 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) HTH_23 PF13384.1 EMR64515.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.10 EMR64515.1 - 0.065 13.0 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Phage_AlpA PF05930.7 EMR64515.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) WGG PF10273.4 EMR64516.1 - 6.1e-31 106.3 0.0 8.7e-31 105.8 0.0 1.2 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 KfrA_N PF11740.3 EMR64516.1 - 0.0016 18.8 0.1 0.004 17.5 0.0 1.5 1 1 0 1 1 1 1 Plasmid replication region DNA-binding N-term CENP-B_dimeris PF09026.5 EMR64516.1 - 2.9 8.1 7.1 6.8 6.9 4.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Glyco_hydro_3_C PF01915.17 EMR64517.1 - 3.2e-57 193.6 0.1 6e-57 192.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EMR64517.1 - 2.4e-56 190.9 0.0 6.4e-35 120.5 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 EMR64517.1 - 1.9e-22 78.9 1.6 2.1e-22 78.8 0.1 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.8 EMR64517.1 - 0.065 12.1 0.0 0.19 10.6 0.0 1.7 1 0 0 1 1 1 0 Putative sugar-binding domain Pkinase PF00069.20 EMR64518.1 - 3.1e-58 196.9 0.0 4.2e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64518.1 - 7.7e-31 107.0 0.0 1e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR64518.1 - 8.7e-05 21.6 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMR64518.1 - 0.011 15.5 2.6 0.011 15.4 0.2 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EMR64518.1 - 0.06 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tubulin PF00091.20 EMR64519.1 - 1.6e-70 237.3 0.0 2.7e-70 236.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMR64519.1 - 3.6e-49 165.9 0.1 6.1e-49 165.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EMR64519.1 - 1.7e-05 24.8 0.0 4.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EMR64519.1 - 0.0043 16.5 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF1604 PF07713.8 EMR64520.1 - 1.5e-34 117.5 13.1 1.7e-29 101.4 2.3 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1604) G-patch PF01585.18 EMR64520.1 - 2.7e-06 27.0 2.7 2.7e-06 27.0 1.9 2.7 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.2 EMR64520.1 - 0.011 15.5 0.3 0.011 15.5 0.2 3.5 5 1 0 5 5 5 0 DExH-box splicing factor binding site Ank PF00023.25 EMR64521.1 - 1.4e-22 78.3 4.1 8.6e-07 28.4 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.2 EMR64521.1 - 3.1e-22 78.6 2.0 2.4e-08 34.1 0.2 4.3 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMR64521.1 - 2.8e-17 62.6 2.1 3.5e-05 24.1 0.0 4.7 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR64521.1 - 4.4e-17 60.4 1.1 0.00059 19.8 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EMR64521.1 - 5.2e-12 45.6 1.7 0.028 14.6 0.0 4.8 4 1 0 4 4 4 3 Ankyrin repeats (many copies) F-box-like PF12937.2 EMR64521.1 - 1.1e-05 25.0 0.0 3.5e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like Asparaginase_II PF06089.7 EMR64522.1 - 2e-110 368.5 0.7 2.4e-110 368.2 0.5 1.1 1 0 0 1 1 1 1 L-asparaginase II MRP-L27 PF09809.4 EMR64523.1 - 1.1e-16 60.4 0.3 1.3e-16 60.1 0.2 1.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 B12D PF06522.6 EMR64524.1 - 1.6e-07 30.8 0.0 2.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Glyco_hydro_10 PF00331.15 EMR64525.1 - 4.7e-95 318.2 0.0 5.4e-95 318.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 FAR1 PF03101.10 EMR64526.1 - 2.1e-05 24.9 0.2 3.3e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 EMR64526.1 - 0.0058 16.8 0.2 0.0083 16.3 0.1 1.3 1 0 0 1 1 1 1 Transcription factor AFT WASH_WAHD PF11945.3 EMR64526.1 - 0.0062 15.8 0.0 0.0087 15.3 0.0 1.1 1 0 0 1 1 1 1 WAHD domain of WASH complex Matrilin_ccoil PF10393.4 EMR64526.1 - 0.079 12.3 0.0 5.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin MFS_1 PF07690.11 EMR64527.1 - 3.1e-45 154.4 58.1 3e-43 147.8 39.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Arrestin_C PF02752.17 EMR64528.1 - 4e-09 36.6 0.3 2.3e-08 34.2 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EMR64528.1 - 4.1e-05 23.4 0.0 0.047 13.5 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Rhomboid PF01694.17 EMR64529.1 - 9.9e-39 132.6 17.0 1.6e-37 128.7 7.1 2.9 3 0 0 3 3 3 2 Rhomboid family Corona_S2 PF01601.11 EMR64529.1 - 1.8 6.5 6.0 2.6 6.0 4.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein SnoaL_4 PF13577.1 EMR64530.1 - 3.1e-07 30.3 0.0 5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Cnd3 PF12719.2 EMR64531.1 - 1.3e-90 303.3 0.2 6.2e-90 301.1 0.0 2.2 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EMR64531.1 - 1.4e-09 38.1 14.4 1e-05 25.7 0.5 5.7 4 2 2 6 6 6 2 HEAT repeats HEAT PF02985.17 EMR64531.1 - 6.9e-07 28.8 5.0 0.16 12.1 0.0 6.9 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.2 EMR64531.1 - 0.019 14.7 0.2 0.63 9.8 0.2 3.4 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.1 EMR64531.1 - 0.026 13.8 0.8 0.66 9.1 0.1 3.1 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF1546 PF07571.8 EMR64531.1 - 0.05 13.7 0.5 0.66 10.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 EMR64531.1 - 2.8 8.5 20.7 0.24 11.9 0.9 7.1 4 1 3 7 7 7 0 HEAT-like repeat Iso_dh PF00180.15 EMR64532.1 - 6.3e-70 235.8 0.0 7.5e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2543 PF10820.3 EMR64532.1 - 0.12 12.4 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) Ank PF00023.25 EMR64533.1 - 0.0088 15.8 3.4 0.9 9.4 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EMR64533.1 - 0.11 12.9 0.0 2.9 8.2 0.0 2.9 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Arrestin_N PF00339.24 EMR64534.1 - 3.2e-13 49.7 0.0 1.4e-07 31.4 0.0 3.3 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EMR64534.1 - 0.017 15.1 0.1 1.8 8.6 0.8 3.1 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Bul1_C PF04426.7 EMR64534.1 - 0.043 12.9 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Bul1 C terminus FAM110_C PF14160.1 EMR64534.1 - 0.14 13.0 0.2 0.29 12.0 0.1 1.4 1 0 0 1 1 1 0 Centrosome-associated C terminus zf-DHHC PF01529.15 EMR64534.1 - 0.21 10.9 0.1 0.34 10.2 0.1 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase HABP4_PAI-RBP1 PF04774.10 EMR64535.1 - 0.013 15.9 3.0 0.02 15.3 2.1 1.4 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family Meth_synt_2 PF01717.13 EMR64536.1 - 3.7e-10 39.3 0.0 5.6e-07 28.8 0.0 2.6 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EMR64536.1 - 0.0089 15.3 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Glyco_hydro_18 PF00704.23 EMR64537.1 - 2e-34 119.6 3.5 2e-34 119.6 2.4 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.15 EMR64537.1 - 1.2e-18 66.6 0.1 1e-08 34.8 0.0 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EMR64537.1 - 0.00012 21.9 3.3 0.00012 21.9 2.3 3.7 3 0 0 3 3 3 1 Chitin recognition protein CIAPIN1 PF05093.8 EMR64539.1 - 4.5e-34 116.5 3.1 6.8e-34 115.9 2.2 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis AMP-binding PF00501.23 EMR64540.1 - 5.3e-72 242.4 0.0 6.3e-36 123.6 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EMR64540.1 - 3.9e-11 43.7 0.9 8.2e-11 42.6 0.7 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_3 PF07859.8 EMR64541.1 - 2.3e-48 164.5 0.1 3e-48 164.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMR64541.1 - 4.4e-11 42.1 0.1 1.1e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EMR64541.1 - 4.4e-06 26.5 0.2 6.1e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 EMR64542.1 - 2.7e-29 99.9 3.3 2.7e-06 27.0 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMR64542.1 - 0.0058 15.4 0.1 0.19 10.4 0.0 2.3 2 1 0 2 2 2 2 Nup133 N terminal like adh_short PF00106.20 EMR64544.1 - 1.4e-21 77.1 0.1 2.2e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR64544.1 - 9.2e-14 51.7 0.1 1.2e-13 51.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EMR64544.1 - 3.7e-08 32.8 0.0 9.7e-06 24.9 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) KR PF08659.5 EMR64544.1 - 7.9e-07 28.9 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR64544.1 - 8.5e-05 22.6 0.1 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR64544.1 - 0.035 13.3 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Hce2 PF14856.1 EMR64545.1 - 1.4e-17 63.3 0.0 1.9e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Adeno_E3_CR1 PF02440.10 EMR64545.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 NmrA PF05368.8 EMR64546.1 - 1.8e-28 99.4 0.0 2.1e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR64546.1 - 6.2e-05 23.0 0.0 8.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMR64546.1 - 0.024 14.2 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 EMR64546.1 - 0.15 11.9 0.1 0.33 10.8 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Tubulin PF00091.20 EMR64547.1 - 8.4e-74 248.0 0.0 1.2e-73 247.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMR64547.1 - 6e-46 155.5 0.3 1.3e-45 154.5 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EMR64547.1 - 3.2e-08 33.6 0.0 7.1e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain PepX_C PF08530.5 EMR64548.1 - 6.5e-19 68.6 0.0 9.2e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 EMR64548.1 - 0.0036 16.7 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FA_hydroxylase PF04116.8 EMR64553.1 - 0.022 15.1 0.2 0.022 15.1 0.1 2.3 2 1 0 2 2 2 0 Fatty acid hydroxylase superfamily TMP-TENI PF02581.12 EMR64553.1 - 0.12 11.4 0.0 2.8 7.0 0.0 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Glyco_hydro_2_N PF02837.13 EMR64554.1 - 2.6e-36 124.7 0.0 5.1e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EMR64554.1 - 5.6e-28 97.6 0.0 1.8e-27 96.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EMR64554.1 - 1.2e-18 67.5 0.2 2.4e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EMR64554.1 - 3.5e-05 24.0 0.0 0.00011 22.3 0.0 2.0 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Abhydrolase_6 PF12697.2 EMR64555.1 - 1.8e-12 47.6 0.3 3e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR64555.1 - 3.2e-08 33.4 0.0 6.9e-07 29.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR64555.1 - 0.0013 18.3 0.0 0.0094 15.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMR64555.1 - 0.023 13.9 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family IER PF05760.7 EMR64556.1 - 0.02 14.8 5.6 0.022 14.6 3.9 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF4407 PF14362.1 EMR64556.1 - 3.8 6.3 8.4 4.7 6.0 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ketoacyl-synt PF00109.21 EMR64557.1 - 1.4e-64 218.0 0.8 3.7e-64 216.6 0.6 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMR64557.1 - 1.8e-58 198.3 0.2 1.1e-57 195.7 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 EMR64557.1 - 2.2e-55 187.1 0.2 7e-55 185.4 0.2 2.0 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EMR64557.1 - 5.8e-41 140.5 2.1 1.1e-40 139.6 1.5 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EMR64557.1 - 1.9e-40 138.5 4.4 2.6e-40 138.0 0.1 3.3 4 0 0 4 4 4 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMR64557.1 - 4e-35 120.2 0.0 1.3e-34 118.6 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EMR64557.1 - 4.6e-17 61.7 0.7 2e-16 59.7 0.2 2.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMR64557.1 - 2.6e-15 56.6 0.0 8.4e-15 55.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR64557.1 - 4.1e-11 42.8 0.0 1.1e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR64557.1 - 1.8e-10 41.1 0.0 5.4e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR64557.1 - 9.2e-10 38.3 0.0 2.1e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR64557.1 - 9.2e-08 32.2 0.0 4.1e-07 30.1 0.0 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EMR64557.1 - 2.1e-07 31.5 0.0 8.1e-07 29.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR64557.1 - 8.3e-06 25.0 0.0 1.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 EMR64557.1 - 7e-05 21.9 0.1 0.00017 20.6 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EMR64557.1 - 0.006 16.2 2.4 0.0083 15.7 0.6 2.1 2 0 0 2 2 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF915 PF06028.6 EMR64557.1 - 1.1 8.3 0.0 1.9 7.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.2 EMR64558.1 - 1e-07 32.1 0.7 1.2e-07 31.8 0.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR64558.1 - 0.073 12.6 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Tautomerase_3 PF14832.1 EMR64559.1 - 7.3e-12 45.4 0.0 9.8e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme MFS_1 PF07690.11 EMR64560.1 - 2e-10 39.9 11.7 2.9e-10 39.3 8.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR64560.1 - 0.55 8.7 15.0 0.2 10.1 0.9 1.6 1 1 1 2 2 2 0 Sugar (and other) transporter DUF202 PF02656.10 EMR64560.1 - 4.5 7.5 6.5 2.3 8.5 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Sugar_tr PF00083.19 EMR64561.1 - 3.8e-96 322.4 19.1 4.6e-96 322.1 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR64561.1 - 1.5e-26 92.9 51.5 1.1e-22 80.2 18.5 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMR64561.1 - 0.04 13.6 0.1 0.04 13.6 0.1 3.5 3 0 0 3 3 3 0 MFS_1 like family VCBS PF13517.1 EMR64562.1 - 1.9e-31 108.1 61.5 4.5e-11 42.9 1.3 7.2 3 2 4 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EMR64562.1 - 4e-16 58.1 35.6 0.0016 18.0 0.6 7.2 7 0 0 7 7 7 5 FG-GAP repeat Lipase_GDSL_2 PF13472.1 EMR64562.1 - 9.7e-12 45.3 0.6 2.4e-11 44.0 0.4 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMR64562.1 - 1.1e-11 45.0 0.2 1.9e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.3 EMR64562.1 - 7.3e-06 25.5 16.1 0.091 12.1 0.0 6.3 6 1 1 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region BBS2_C PF14782.1 EMR64562.1 - 0.074 11.5 0.6 13 4.2 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal DUF3688 PF12461.3 EMR64562.1 - 0.1 12.9 0.4 2.8 8.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3688) Ank_2 PF12796.2 EMR64563.1 - 2.8e-21 75.6 3.9 3.8e-12 46.3 0.7 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMR64563.1 - 6.4e-13 48.8 0.7 9.8e-08 32.3 0.0 4.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR64563.1 - 1e-10 41.4 1.8 9.8e-07 28.8 0.2 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) CorA PF01544.13 EMR64563.1 - 3.8e-09 36.0 0.1 8.8e-09 34.7 0.1 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ank PF00023.25 EMR64563.1 - 4.9e-09 35.5 1.8 0.00017 21.2 0.0 5.0 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.1 EMR64563.1 - 3.6e-08 32.8 1.0 0.056 13.6 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat TPR_12 PF13424.1 EMR64563.1 - 2.3e-06 27.4 0.1 0.00068 19.5 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMR64563.1 - 0.025 15.1 0.4 5.7 7.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMR64563.1 - 0.026 14.3 0.1 6 6.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.20 EMR64565.1 - 1.8e-16 60.5 0.0 2.2e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR64565.1 - 8.1e-09 35.3 0.0 1.1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF2456 PF10445.4 EMR64566.1 - 1.8e-07 30.9 2.1 4.8e-07 29.6 1.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2456) cobW PF02492.14 EMR64567.1 - 1.1e-34 119.3 0.0 1.4e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EMR64567.1 - 7.9e-07 28.1 0.2 0.00092 18.0 0.1 2.0 2 0 0 2 2 2 2 ArgK protein AAA_23 PF13476.1 EMR64567.1 - 0.013 15.8 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EMR64567.1 - 0.026 14.4 0.0 0.067 13.1 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 EMR64567.1 - 0.035 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain TMEM51 PF15345.1 EMR64567.1 - 0.081 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 IstB_IS21 PF01695.12 EMR64567.1 - 0.12 11.8 0.0 0.26 10.6 0.0 1.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 EMR64567.1 - 0.12 13.1 0.1 0.21 12.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMR64567.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) CbiA PF01656.18 EMR64567.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_21 PF13304.1 EMR64567.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 EMR64567.1 - 0.16 11.2 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein CENP-C_C PF11699.3 EMR64568.1 - 3.9e-31 106.8 0.9 7e-31 106.0 0.2 1.7 2 0 0 2 2 2 1 Mif2/CENP-C like Mif2_N PF15624.1 EMR64568.1 - 6.9e-27 94.6 2.5 6.9e-27 94.6 1.7 3.7 2 1 2 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 EMR64568.1 - 7.8e-08 31.7 0.0 1.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EMR64568.1 - 0.019 14.3 0.0 0.047 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF861) BING4CT PF08149.6 EMR64569.1 - 1.5e-39 133.3 0.0 3.4e-37 125.8 0.0 3.5 3 0 0 3 3 3 1 BING4CT (NUC141) domain Coatomer_WDAD PF04053.9 EMR64569.1 - 0.0067 15.2 0.1 0.031 13.0 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region ParBc_2 PF08857.6 EMR64569.1 - 0.011 15.5 0.2 0.035 13.9 0.1 2.0 1 1 0 1 1 1 0 Putative ParB-like nuclease WD40 PF00400.27 EMR64569.1 - 0.041 13.7 0.0 20 5.2 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat HET PF06985.6 EMR64570.1 - 4.7e-20 72.1 0.1 1.2e-19 70.8 0.1 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RNase_HII PF01351.13 EMR64571.1 - 5e-43 147.0 0.0 2.3e-38 131.8 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease HII DUF663 PF04950.7 EMR64572.1 - 2.1e-101 338.8 0.0 3.1e-101 338.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EMR64572.1 - 1.2e-22 79.2 0.0 2.7e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Sigma_reg_N PF13800.1 EMR64573.1 - 0.0023 17.9 0.5 0.66 10.0 0.0 3.1 3 0 0 3 3 3 2 Sigma factor regulator N-terminal DUF4448 PF14610.1 EMR64573.1 - 0.04 13.4 2.0 0.064 12.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) Peroxin-13_N PF04088.8 EMR64573.1 - 0.35 10.8 1.5 0.93 9.4 0.1 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region RHD3 PF05879.7 EMR64574.1 - 3.6e-291 967.5 0.0 6.6e-289 960.0 0.0 2.0 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EMR64574.1 - 1.3e-07 30.9 0.1 2.3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EMR64574.1 - 7.4e-07 29.1 0.0 1.6e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EMR64574.1 - 1.3e-06 28.3 0.0 3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMR64574.1 - 0.00024 21.5 0.1 0.00048 20.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EMR64574.1 - 0.00037 20.4 0.0 0.0014 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain Cys_Met_Meta_PP PF01053.15 EMR64574.1 - 0.058 11.6 0.1 0.091 11.0 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Septin PF00735.13 EMR64574.1 - 0.094 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Septin NUC173 PF08161.7 EMR64574.1 - 0.1 11.9 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 NUC173 domain NACHT PF05729.7 EMR64575.1 - 3.2e-07 30.1 0.0 6.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMR64575.1 - 0.00021 21.3 1.1 0.0018 18.2 0.0 2.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMR64575.1 - 0.0015 18.6 0.0 0.0058 16.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMR64575.1 - 0.054 13.2 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 EMR64575.1 - 0.079 11.8 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 EMR64575.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRF-TF PF00319.13 EMR64576.1 - 4.3e-24 83.4 0.1 5.3e-24 83.1 0.1 1.1 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3591 PF12157.3 EMR64578.1 - 1e-175 584.5 1.2 1.6e-175 583.9 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Ala_racemase_N PF01168.15 EMR64579.1 - 1.3e-13 51.0 0.0 1.9e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Metallophos PF00149.23 EMR64580.1 - 2.7e-09 36.7 0.0 3.8e-07 29.7 0.0 2.6 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMR64580.1 - 5.9e-07 29.4 0.0 1.9e-06 27.7 0.0 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain PT PF04886.7 EMR64580.1 - 1.5 8.1 10.6 2.7 7.3 7.3 1.4 1 0 0 1 1 1 0 PT repeat VSP PF03302.8 EMR64581.1 - 9.8 4.6 14.1 0.031 12.9 0.5 2.1 2 0 0 2 2 2 0 Giardia variant-specific surface protein Transaldolase PF00923.14 EMR64582.1 - 6e-92 307.8 1.0 7e-92 307.6 0.7 1.0 1 0 0 1 1 1 1 Transaldolase GMC_oxred_N PF00732.14 EMR64584.1 - 1.2e-40 139.5 0.1 2.1e-33 115.7 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR64584.1 - 1.4e-23 83.8 0.0 3.7e-23 82.4 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EMR64584.1 - 8.6e-06 24.8 0.2 0.0023 16.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMR64584.1 - 1.4e-05 24.1 0.0 2.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMR64584.1 - 3.1e-05 23.9 0.0 0.00017 21.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMR64584.1 - 0.00074 19.8 0.0 0.34 11.3 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase BolA PF01722.13 EMR64585.1 - 4.7e-28 96.9 0.5 5.6e-28 96.7 0.4 1.1 1 0 0 1 1 1 1 BolA-like protein Sulfotransfer_3 PF13469.1 EMR64586.1 - 4e-05 24.5 2.2 0.00013 22.9 1.5 1.9 1 1 0 1 1 1 1 Sulfotransferase family RNA_pol_Rpc34 PF05158.7 EMR64587.1 - 3.8e-79 266.2 0.0 4.6e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 EMR64587.1 - 0.00019 21.2 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_27 PF13463.1 EMR64587.1 - 0.013 15.7 0.1 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_24 PF13412.1 EMR64587.1 - 0.037 13.4 0.2 0.092 12.1 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GntR PF00392.16 EMR64587.1 - 0.1 12.0 0.1 17 4.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_36 PF13730.1 EMR64587.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain PIP5K PF01504.13 EMR64590.1 - 6e-61 205.7 0.5 1.8e-60 204.1 0.4 1.7 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF2404 PF10296.4 EMR64591.1 - 0.0099 15.9 0.0 0.052 13.6 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Myc_N PF01056.13 EMR64591.1 - 4.6 6.3 4.7 6.4 5.8 0.1 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Oxidored_FMN PF00724.15 EMR64592.1 - 4e-70 236.4 0.0 4.9e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.16 EMR64592.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme AMP-binding PF00501.23 EMR64594.1 - 1.3e-67 227.9 0.0 2.4e-67 227.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMR64594.1 - 1.8e-12 48.0 0.1 5.9e-12 46.3 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans_2 PF11951.3 EMR64595.1 - 1.8e-38 132.1 0.0 9.8e-37 126.4 0.0 3.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR64595.1 - 2.2e-07 30.6 6.7 2.2e-07 30.6 4.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ctr PF04145.10 EMR64596.1 - 2.9e-41 140.9 0.4 3.8e-41 140.4 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Sensor PF13796.1 EMR64596.1 - 0.0043 16.6 0.4 0.55 9.8 0.0 2.1 2 0 0 2 2 2 2 Putative sensor Cytochrom_B_N PF00033.14 EMR64596.1 - 0.018 14.4 1.4 0.038 13.3 0.3 2.1 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF1673 PF07895.6 EMR64596.1 - 0.061 12.8 0.1 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF3169 PF11368.3 EMR64596.1 - 0.12 11.5 1.6 0.89 8.7 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF1049 PF06305.6 EMR64596.1 - 0.16 11.4 4.7 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF2273 PF10031.4 EMR64596.1 - 0.33 10.5 9.0 4.6 6.9 2.5 2.5 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) DUF2530 PF10745.4 EMR64596.1 - 1.8 8.5 6.9 2.9 7.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF3021 PF11457.3 EMR64596.1 - 6.7 6.5 9.4 23 4.8 5.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) DUF4407 PF14362.1 EMR64596.1 - 7.4 5.4 5.6 13 4.6 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MFS_1 PF07690.11 EMR64597.1 - 2.2e-46 158.1 64.3 2.6e-45 154.6 41.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR64597.1 - 4.7e-21 74.6 19.0 6.4e-21 74.1 13.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMR64597.1 - 1.2e-14 53.7 13.0 1.2e-14 53.7 9.0 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter GST_N_2 PF13409.1 EMR64598.1 - 7.4e-22 77.1 0.0 1.9e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR64598.1 - 2.8e-14 52.7 0.1 1.7e-13 50.2 0.2 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMR64598.1 - 2.8e-05 24.2 0.0 0.0013 18.9 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMR64598.1 - 6.1e-05 23.4 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMR64598.1 - 0.00037 20.4 0.0 0.0007 19.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MARVEL PF01284.18 EMR64599.1 - 5.3e-05 23.0 8.5 0.00014 21.6 5.9 1.7 1 1 0 1 1 1 1 Membrane-associating domain BCLP PF12304.3 EMR64599.1 - 0.42 10.0 3.2 0.72 9.2 2.2 1.3 1 0 0 1 1 1 0 Beta-casein like protein Zip PF02535.17 EMR64601.1 - 1.5e-30 106.3 0.0 1.8e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.7 EMR64601.1 - 0.019 14.2 4.4 0.036 13.3 3.1 1.4 1 0 0 1 1 1 0 HupE / UreJ protein Peptidase_S8 PF00082.17 EMR64605.1 - 5.5e-45 153.6 15.9 7.1e-45 153.3 11.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMR64605.1 - 5.7e-17 62.0 0.1 1.3e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Plug_translocon PF10559.4 EMR64606.1 - 0.1 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Plug domain of Sec61p PAT1 PF09770.4 EMR64606.1 - 0.85 7.7 21.9 1 7.5 15.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GST_N_2 PF13409.1 EMR64607.1 - 2.5e-06 27.3 0.0 5.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMR64607.1 - 1.1e-05 25.5 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR64607.1 - 8.1e-05 22.5 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMR64607.1 - 0.00028 20.7 0.0 0.00053 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMR64607.1 - 0.00079 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Pyr_redox_3 PF13738.1 EMR64608.1 - 4.3e-13 49.7 0.0 1.4e-12 48.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR64608.1 - 1.7e-09 37.0 0.1 5.9e-05 22.1 0.0 2.9 1 1 2 3 3 3 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR64608.1 - 2.2e-09 37.2 0.0 6e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMR64608.1 - 1.2e-05 24.5 0.0 0.00077 18.6 0.0 2.3 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase FMO-like PF00743.14 EMR64608.1 - 0.00019 19.8 0.1 0.0053 15.0 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.7 EMR64608.1 - 0.00079 18.4 0.0 0.013 14.4 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 EMR64608.1 - 0.00085 18.2 0.0 0.29 9.9 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EMR64608.1 - 0.0022 17.9 0.1 0.3 10.9 0.0 2.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR64608.1 - 0.0029 17.9 0.0 0.07 13.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR64608.1 - 0.0031 16.6 0.0 0.014 14.5 0.0 2.0 3 0 0 3 3 3 1 Thi4 family K_oxygenase PF13434.1 EMR64608.1 - 0.017 14.0 0.3 6.8 5.4 0.0 3.0 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Mqo PF06039.10 EMR64608.1 - 0.066 11.3 0.0 6.3 4.8 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.19 EMR64608.1 - 0.1 11.4 0.0 0.27 10.0 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 EMR64608.1 - 0.26 11.0 1.4 16 5.2 0.0 3.0 2 1 0 3 3 3 0 FAD-NAD(P)-binding MFS_1 PF07690.11 EMR64609.1 - 8.7e-41 139.7 51.9 2.2e-39 135.1 36.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR64609.1 - 3.1e-14 52.1 20.3 2.4e-13 49.1 13.7 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4448 PF14610.1 EMR64609.1 - 0.017 14.5 0.1 0.085 12.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) ENTH PF01417.15 EMR64610.1 - 9.1e-31 106.3 0.2 1.6e-30 105.5 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EMR64610.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 ANTH domain Pkinase PF00069.20 EMR64611.1 - 4e-37 127.7 0.0 5.4e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64611.1 - 8.9e-18 64.2 0.0 1.9e-17 63.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR64611.1 - 0.00018 20.5 0.1 0.0014 17.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like IF4E PF01652.13 EMR64613.1 - 1e-59 200.7 0.1 1.2e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DAO PF01266.19 EMR64614.1 - 3.1e-17 62.5 0.0 1e-15 57.5 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR64614.1 - 7.4e-05 23.0 0.1 0.00016 21.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EMR64614.1 - 0.0018 17.7 0.0 0.0049 16.3 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 EMR64614.1 - 0.0034 16.3 0.1 0.0077 15.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMR64614.1 - 0.0036 17.2 0.1 0.0084 16.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR64614.1 - 0.0046 16.8 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EMR64614.1 - 0.0052 16.4 0.0 0.008 15.8 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMR64614.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EMR64614.1 - 0.031 13.6 0.2 0.049 13.0 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 EMR64614.1 - 0.034 13.1 0.5 0.053 12.5 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 EMR64614.1 - 0.043 14.0 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.12 EMR64614.1 - 0.055 12.5 0.1 0.088 11.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 EMR64614.1 - 0.059 12.9 0.1 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 EMR64614.1 - 0.082 12.9 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding GIDA PF01134.17 EMR64614.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pro_isomerase PF00160.16 EMR64615.1 - 6.8e-39 133.5 0.4 7.8e-39 133.3 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FAM101 PF15068.1 EMR64616.1 - 0.055 12.9 0.6 0.087 12.2 0.4 1.3 1 0 0 1 1 1 0 FAM101 family DUF310 PF03750.8 EMR64617.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF310) DUF1195 PF06708.6 EMR64617.1 - 0.15 11.4 0.4 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1195) Menin PF05053.8 EMR64617.1 - 0.28 9.2 1.3 0.39 8.8 0.9 1.1 1 0 0 1 1 1 0 Menin DUF605 PF04652.11 EMR64617.1 - 2 7.7 14.7 2.6 7.3 10.2 1.1 1 0 0 1 1 1 0 Vta1 like TPR_11 PF13414.1 EMR64618.1 - 3e-55 183.7 29.5 2.2e-17 62.4 0.4 6.6 7 0 0 7 7 7 6 TPR repeat TPR_1 PF00515.23 EMR64618.1 - 3.6e-43 143.4 29.0 1.9e-06 27.2 0.1 10.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 EMR64618.1 - 1.9e-34 114.7 26.1 4.2e-05 23.1 0.0 10.1 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 EMR64618.1 - 6.1e-18 64.5 10.7 5.3e-09 35.8 0.4 6.2 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMR64618.1 - 8.9e-18 64.4 9.0 0.00061 20.3 0.0 6.5 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EMR64618.1 - 3.5e-15 55.1 13.3 0.28 11.9 0.0 9.2 7 3 4 11 11 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 EMR64618.1 - 4.7e-15 54.4 6.6 0.0073 16.4 0.0 8.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMR64618.1 - 5.5e-14 51.7 0.7 0.0003 20.5 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMR64618.1 - 1.1e-13 49.8 24.6 3.2e-05 23.4 0.1 8.3 9 1 1 10 10 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMR64618.1 - 7.8e-12 44.0 8.9 0.0031 17.1 0.0 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR64618.1 - 1.6e-10 41.2 11.2 0.094 13.0 0.3 6.7 4 3 3 7 7 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EMR64618.1 - 7.8e-06 25.9 10.8 0.0039 17.2 1.4 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMR64618.1 - 0.0023 18.2 14.5 1.8 9.2 0.0 7.1 8 0 0 8 8 6 1 Tetratricopeptide repeat Tcf25 PF04910.9 EMR64618.1 - 0.025 13.5 0.2 0.049 12.5 0.2 1.6 1 0 0 1 1 1 0 Transcriptional repressor TCF25 SHNi-TPR PF10516.4 EMR64618.1 - 0.038 13.2 0.7 16 4.8 0.0 4.0 4 0 0 4 4 4 0 SHNi-TPR XPC-binding PF09280.6 EMR64618.1 - 7.1 6.1 14.0 5.3 6.5 1.5 3.9 3 1 1 4 4 4 0 XPC-binding domain p450 PF00067.17 EMR64619.1 - 1.6e-51 175.3 0.0 4e-33 114.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 60KD_IMP PF02096.15 EMR64620.1 - 5.1e-13 49.1 0.0 8.8e-13 48.3 0.0 1.4 1 1 0 1 1 1 1 60Kd inner membrane protein DUF4129 PF13559.1 EMR64621.1 - 0.002 18.0 0.0 0.006 16.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) NICE-3 PF07406.6 EMR64621.1 - 0.069 12.6 0.5 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 NICE-3 protein DUF829 PF05705.9 EMR64623.1 - 8.2e-33 114.0 0.0 9.9e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Syntaxin_2 PF14523.1 EMR64624.1 - 5.3e-24 84.2 8.3 8.3e-24 83.5 0.8 2.4 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EMR64624.1 - 3.5e-16 58.6 3.3 8.7e-16 57.3 2.3 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EMR64624.1 - 0.00069 19.7 7.8 0.00086 19.4 0.2 2.5 2 1 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 EMR64624.1 - 0.019 14.5 0.1 0.1 12.1 0.2 2.1 2 0 0 2 2 2 0 Synaptobrevin SH3BGR PF04908.10 EMR64624.1 - 0.054 13.4 2.4 1.2 9.0 0.1 2.4 1 1 1 2 2 2 0 SH3-binding, glutamic acid-rich protein T2SF PF00482.18 EMR64624.1 - 0.094 12.6 0.5 0.4 10.6 0.4 2.2 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F MCPsignal PF00015.16 EMR64624.1 - 0.15 11.5 4.0 0.25 10.8 0.4 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2580 PF10824.3 EMR64624.1 - 0.22 11.9 1.9 0.73 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) DUF1664 PF07889.7 EMR64624.1 - 1.1 9.0 4.2 1 9.1 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spectrin PF00435.16 EMR64624.1 - 5.6 7.2 9.1 0.8 10.0 1.6 2.4 2 1 1 3 3 3 0 Spectrin repeat Ndc1_Nup PF09531.5 EMR64625.1 - 4.5e-122 408.4 0.0 5.1e-122 408.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Glycos_transf_1 PF00534.15 EMR64626.1 - 1.8e-19 69.8 0.0 3.1e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMR64626.1 - 3.6e-10 40.1 0.1 6.3e-09 36.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Adap_comp_sub PF00928.16 EMR64627.1 - 2.4e-17 62.8 0.0 3.8e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMR64627.1 - 2.5e-07 30.4 0.2 4.4e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 EMR64627.1 - 0.017 15.2 0.2 0.035 14.2 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) ADH_N PF08240.7 EMR64628.1 - 2.5e-29 101.2 0.6 4.6e-29 100.3 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR64628.1 - 7.7e-26 90.1 0.2 1.3e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 EMR64628.1 - 0.36 10.6 1.9 0.81 9.5 1.3 1.5 1 0 0 1 1 1 0 ThiF family Pro_isomerase PF00160.16 EMR64630.1 - 8.9e-43 146.1 0.0 2.1e-42 144.9 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 EMR64630.1 - 5.2e-06 26.3 0.0 1.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 U-box domain AMP-binding PF00501.23 EMR64631.1 - 1.5e-67 227.8 0.0 1.8e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMR64631.1 - 1.2e-16 61.3 0.1 2.6e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain KTI12 PF08433.5 EMR64632.1 - 4e-72 242.6 0.0 6.1e-72 242.0 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EMR64632.1 - 1.6e-05 24.7 0.0 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMR64632.1 - 0.0011 19.3 0.1 0.0043 17.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMR64632.1 - 0.0012 19.6 0.0 0.0022 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMR64632.1 - 0.0033 17.5 0.0 0.0064 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR64632.1 - 0.015 15.2 0.2 0.34 10.8 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain DUF1792 PF08759.6 EMR64632.1 - 0.022 14.3 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) AAA_14 PF13173.1 EMR64632.1 - 0.042 13.7 0.2 0.25 11.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain 6PF2K PF01591.13 EMR64632.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Alg6_Alg8 PF03155.10 EMR64633.1 - 4e-37 128.1 6.8 4.9e-37 127.8 4.7 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lung_7-TM_R PF06814.8 EMR64634.1 - 2.7e-53 180.8 16.1 3.2e-41 141.2 7.8 2.1 1 1 1 2 2 2 2 Lung seven transmembrane receptor DUF1980 PF09323.5 EMR64634.1 - 0.078 12.7 0.8 0.16 11.6 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) NADH_dh_m_C1 PF15088.1 EMR64634.1 - 0.49 9.9 2.8 0.52 9.8 0.3 2.1 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial DUF1673 PF07895.6 EMR64634.1 - 2.6 7.5 9.8 0.25 10.8 3.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF4131 PF13567.1 EMR64634.1 - 4.8 6.5 14.9 1.9 7.8 3.9 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF373 PF04123.8 EMR64635.1 - 0.029 13.3 5.0 0.038 13.0 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF3397 PF11877.3 EMR64635.1 - 1.2 9.1 7.2 1.1 9.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3397) CAAD PF14159.1 EMR64635.1 - 3.7 7.2 7.0 2.2 7.9 0.2 3.6 3 1 1 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Methyltransf_28 PF02636.12 EMR64636.1 - 3.5e-80 269.0 0.0 4.2e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Lectin_leg-like PF03388.8 EMR64637.1 - 9.1e-22 77.3 0.0 1.8e-21 76.3 0.0 1.5 2 0 0 2 2 2 1 Legume-like lectin family Tropomyosin_1 PF12718.2 EMR64637.1 - 0.0062 16.3 0.2 0.0062 16.3 0.1 2.1 2 0 0 2 2 2 1 Tropomyosin like Baculo_PEP_C PF04513.7 EMR64637.1 - 0.015 15.1 0.1 3.1 7.6 0.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EMR64637.1 - 0.031 13.8 4.3 0.092 12.3 3.0 1.7 1 1 0 1 1 1 0 IncA protein Transcrip_act PF04949.8 EMR64637.1 - 0.067 12.8 0.1 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 Transcriptional activator BAF1_ABF1 PF04684.8 EMR64637.1 - 0.73 8.6 7.6 1 8.1 5.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4175 PF13779.1 EMR64637.1 - 1.9 6.0 15.1 2.8 5.5 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Apc4 PF12896.2 EMR64639.1 - 5.5e-24 84.6 0.0 1.1e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 WD40 PF00400.27 EMR64639.1 - 0.015 15.1 0.1 0.18 11.7 0.0 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat TruB-C_2 PF09157.6 EMR64639.1 - 0.031 14.1 0.5 6 6.7 0.0 2.9 2 0 0 2 2 2 0 Pseudouridine synthase II TruB, C-terminal T2SS-T3SS_pil_N PF13629.1 EMR64639.1 - 0.13 11.7 0.0 0.37 10.3 0.0 1.7 1 0 0 1 1 1 0 Pilus formation protein N terminal region Pkinase PF00069.20 EMR64640.1 - 1.1e-52 178.8 0.0 1.5e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64640.1 - 9.7e-22 77.2 0.0 2e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMR64640.1 - 0.00099 18.9 0.3 0.00099 18.9 0.2 2.9 3 1 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EMR64640.1 - 0.0032 16.4 0.0 0.0052 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMR64640.1 - 0.0044 16.0 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sporozoite_P67 PF05642.6 EMR64640.1 - 1.9 6.2 6.9 2.7 5.7 4.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SAPS PF04499.10 EMR64640.1 - 2.8 6.4 5.0 3.3 6.2 3.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TLP-20 PF06088.6 EMR64640.1 - 9.7 5.8 8.2 18 4.9 5.7 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) WAC_Acf1_DNA_bd PF10537.4 EMR64641.1 - 2.9e-39 133.3 0.0 9.7e-39 131.6 0.0 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EMR64641.1 - 1e-17 63.6 0.3 1.8e-17 62.8 0.2 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EMR64641.1 - 2e-11 43.2 0.3 4.6e-11 42.1 0.2 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 EMR64641.1 - 0.099 12.6 0.7 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 DUF966 PF06136.8 EMR64642.1 - 0.016 14.6 3.0 0.019 14.3 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) MFS_1 PF07690.11 EMR64643.1 - 1.8e-25 89.4 24.1 3.5e-15 55.5 3.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR64643.1 - 5.2e-07 28.5 8.8 5.2e-07 28.5 6.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Ndc1_Nup PF09531.5 EMR64643.1 - 2 6.7 6.7 0.47 8.8 1.1 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Tom22 PF04281.8 EMR64644.1 - 5.4e-45 152.2 0.1 7.9e-45 151.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Mid2 PF04478.7 EMR64645.1 - 0.0047 16.3 4.9 0.69 9.3 4.4 2.5 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor GRA6 PF05084.8 EMR64645.1 - 0.02 14.4 0.3 0.041 13.4 0.2 1.5 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DUF3348 PF11828.3 EMR64645.1 - 0.069 12.5 0.8 0.12 11.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) PfkB PF00294.19 EMR64646.1 - 1.4e-65 221.3 0.5 1.7e-65 221.1 0.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EMR64646.1 - 8.4e-06 25.1 0.0 1.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DOT1 PF08123.8 EMR64647.1 - 8.2e-70 234.2 0.0 1.3e-69 233.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EMR64647.1 - 0.0088 16.0 0.0 0.037 14.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR64647.1 - 0.013 16.0 0.1 0.066 13.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain RE_SinI PF09570.5 EMR64647.1 - 0.017 14.0 0.0 0.04 12.9 0.0 1.6 1 0 0 1 1 1 0 SinI restriction endonuclease Methyltransf_31 PF13847.1 EMR64647.1 - 0.12 11.9 0.3 0.27 10.8 0.2 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF566 PF04484.7 EMR64647.1 - 3.9 6.9 13.6 6.1 6.2 9.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Scytalone_dh PF02982.9 EMR64648.1 - 2.4e-88 293.7 0.4 2.7e-88 293.5 0.3 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EMR64648.1 - 1.8e-09 37.5 0.3 2.4e-09 37.1 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 EMR64648.1 - 0.028 14.9 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative lumazine-binding Dynamin_N PF00350.18 EMR64649.1 - 1.7e-33 115.8 0.0 3.9e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EMR64649.1 - 1.6e-13 50.0 0.1 4.9e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EMR64649.1 - 8.2e-05 22.5 0.1 0.00041 20.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.1 EMR64649.1 - 0.021 14.8 0.0 0.091 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EMR64649.1 - 0.032 14.7 0.1 0.14 12.7 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein DUF2478 PF10649.4 EMR64649.1 - 0.054 12.8 0.0 0.17 11.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) GED PF02212.13 EMR64649.1 - 0.12 12.3 1.4 0.46 10.4 0.1 2.7 3 0 0 3 3 3 0 Dynamin GTPase effector domain SR-25 PF10500.4 EMR64650.1 - 0.59 9.5 9.0 0.53 9.7 0.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-C2H2 PF00096.21 EMR64650.1 - 0.98 9.9 10.6 3.9 7.9 0.4 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type Ank_2 PF12796.2 EMR64652.1 - 5.8e-71 234.8 0.1 4.1e-16 59.0 0.1 9.8 4 2 4 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EMR64652.1 - 1.2e-59 195.2 12.4 1.2e-09 37.5 0.0 16.0 15 2 1 16 16 16 10 Ankyrin repeat Ank_3 PF13606.1 EMR64652.1 - 2.1e-41 135.7 13.4 9.4e-07 28.4 0.1 16.4 17 1 0 17 17 17 9 Ankyrin repeat Ank_4 PF13637.1 EMR64652.1 - 2.4e-41 139.4 7.4 2e-05 24.9 0.0 13.9 8 3 6 14 14 14 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR64652.1 - 2.3e-38 129.3 9.6 2e-05 24.6 0.0 12.6 10 2 5 15 15 15 9 Ankyrin repeats (many copies) Astro_capsid PF03115.9 EMR64652.1 - 2.4 6.2 4.4 3.4 5.7 3.0 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RRM_5 PF13893.1 EMR64653.1 - 9.6e-06 25.3 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR64653.1 - 1.8e-05 24.2 0.0 3.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR64653.1 - 0.001 18.9 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Complex1_LYR PF05347.10 EMR64654.1 - 8.7e-07 28.6 0.2 2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMR64654.1 - 7.5e-06 26.0 0.2 1.3e-05 25.2 0.2 1.7 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EMR64654.1 - 0.0014 19.0 0.6 0.0018 18.7 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Phosphoesterase PF04185.9 EMR64654.1 - 0.025 13.7 0.1 0.026 13.7 0.1 1.1 1 0 0 1 1 1 0 Phosphoesterase family G10 PF01125.12 EMR64655.1 - 7.4e-61 203.9 4.4 8.3e-61 203.7 3.0 1.0 1 0 0 1 1 1 1 G10 protein p450 PF00067.17 EMR64657.1 - 4e-57 193.7 0.0 5.6e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.16 EMR64658.1 - 1.9e-32 112.0 4.4 3.6e-32 111.1 3.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Pkinase PF00069.20 EMR64659.1 - 3.7e-50 170.5 0.0 5.5e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64659.1 - 5.1e-24 84.7 0.3 1.1e-23 83.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EMR64659.1 - 0.00024 20.9 0.1 0.00024 20.9 0.0 2.6 3 1 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMR64659.1 - 0.0012 18.1 0.3 0.0051 16.1 0.2 1.9 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EMR64659.1 - 0.27 10.7 3.4 0.26 10.8 0.2 2.4 2 1 1 3 3 3 0 Choline/ethanolamine kinase PAT1 PF09770.4 EMR64659.1 - 0.52 8.4 25.2 0.71 8.0 17.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EMR64659.1 - 1.5 8.6 12.5 2.5 7.9 8.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EST1_DNA_bind PF10373.4 EMR64660.1 - 1.2e-22 80.4 1.0 3.8e-22 78.8 0.0 2.1 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EMR64660.1 - 1.1e-10 41.5 0.2 2.4e-10 40.5 0.2 1.5 1 0 0 1 1 1 1 Telomerase activating protein Est1 FAD_binding_4 PF01565.18 EMR64661.1 - 3.6e-08 32.9 4.9 5.4e-07 29.1 0.5 2.5 2 1 1 3 3 3 2 FAD binding domain BBE PF08031.7 EMR64661.1 - 5.1e-07 29.5 0.8 1.4e-06 28.0 0.1 2.0 2 0 0 2 2 2 1 Berberine and berberine like ATG16 PF08614.6 EMR64662.1 - 2.5e-49 167.7 1.9 3e-49 167.5 1.3 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CCDC144C PF14915.1 EMR64662.1 - 1.3e-05 24.3 5.3 6.3e-05 22.0 3.2 1.9 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region bZIP_1 PF00170.16 EMR64662.1 - 0.054 13.4 8.7 1.3 9.0 0.0 3.8 2 1 2 4 4 4 0 bZIP transcription factor GAS PF13851.1 EMR64662.1 - 0.12 11.5 6.8 0.2 10.8 0.4 2.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EMR64662.1 - 0.14 11.1 3.1 0.26 10.3 2.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Nup54 PF13874.1 EMR64662.1 - 0.15 11.7 5.6 0.22 11.1 1.3 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF972 PF06156.8 EMR64662.1 - 0.43 10.9 4.2 17 5.8 1.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EMR64662.1 - 2.1 8.7 8.8 2.2e+02 2.2 0.0 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 EMR64662.1 - 2.1 7.8 5.8 3 7.3 2.3 2.2 1 1 1 2 2 2 0 IncA protein TMF_DNA_bd PF12329.3 EMR64662.1 - 2.3 8.0 10.2 1.4 8.7 2.4 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Cep57_CLD_2 PF14197.1 EMR64662.1 - 3 7.8 14.1 4.7 7.2 3.4 3.9 3 2 0 3 3 3 0 Centrosome localisation domain of PPC89 HET PF06985.6 EMR64663.1 - 9.3e-21 74.4 8.6 6.5e-19 68.4 3.3 2.6 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 EMR64664.1 - 2.9e-27 95.3 0.0 3.7e-22 78.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 PBP_like PF12727.2 EMR64664.1 - 0.15 11.0 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 PBP superfamily domain RRM_1 PF00076.17 EMR64665.1 - 3.7e-61 202.6 0.0 1e-21 76.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR64665.1 - 3.4e-45 151.8 0.0 4.3e-15 55.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR64665.1 - 1.3e-32 111.4 0.0 9e-11 41.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMR64665.1 - 1.4e-08 34.3 0.0 0.0051 16.5 0.0 3.5 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EMR64665.1 - 0.0032 17.3 0.0 3.4 7.6 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_3 PF08777.6 EMR64665.1 - 0.069 12.9 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif RNA_pol_L_2 PF13656.1 EMR64667.1 - 1.3e-30 104.6 0.0 1.8e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EMR64667.1 - 1.2e-11 43.5 0.0 1.6e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PLRV_ORF5 PF01690.12 EMR64668.1 - 3.6 6.6 5.8 6.6 5.7 4.0 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Terpene_synth_C PF03936.11 EMR64669.1 - 1.4e-06 27.7 0.0 4.3e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain 2OG-Fe_Oxy_2 PF10014.4 EMR64670.1 - 5.8e-38 130.2 0.2 7.3e-38 129.9 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe dioxygenase Nha1_C PF08619.5 EMR64671.1 - 4e-88 296.5 43.7 5.5e-84 282.9 21.3 2.0 1 1 1 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EMR64671.1 - 1.3e-65 221.3 19.7 1.6e-65 221.1 13.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pox_A12 PF04651.8 EMR64671.1 - 0.55 10.3 11.7 2.6 8.1 8.1 2.2 1 1 0 1 1 1 0 Poxvirus A12 protein YrhC PF14143.1 EMR64671.1 - 0.61 10.0 3.3 0.42 10.5 0.2 2.3 2 0 0 2 2 2 0 YrhC-like protein p450 PF00067.17 EMR64672.1 - 1.1e-55 189.0 0.0 1.3e-55 188.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L2_C PF03947.13 EMR64674.1 - 8.4e-39 132.3 2.6 1.4e-38 131.6 1.8 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EMR64674.1 - 3.3e-14 52.5 0.1 6.4e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MFS_1 PF07690.11 EMR64675.1 - 7.9e-27 93.8 26.9 7.9e-27 93.8 18.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MerC PF03203.9 EMR64675.1 - 3.6 7.9 10.7 1.1 9.6 1.1 3.6 2 2 0 2 2 2 0 MerC mercury resistance protein UPF0154 PF03672.8 EMR64676.1 - 0.098 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Pkinase PF00069.20 EMR64676.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Myosin_tail_1 PF01576.14 EMR64677.1 - 3.4e-07 28.4 42.9 3.4e-07 28.4 29.7 3.4 2 1 1 3 3 3 2 Myosin tail CENP-F_leu_zip PF10473.4 EMR64677.1 - 6.1e-07 29.3 93.4 0.17 11.7 7.7 8.1 2 2 5 7 7 7 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2353 PF09789.4 EMR64677.1 - 3.2e-06 26.6 60.0 0.0093 15.2 7.2 4.1 1 1 3 4 4 4 4 Uncharacterized coiled-coil protein (DUF2353) IncA PF04156.9 EMR64677.1 - 3.7e-06 26.6 95.2 7.9e-05 22.3 9.0 6.5 1 1 3 5 5 4 3 IncA protein TPR_MLP1_2 PF07926.7 EMR64677.1 - 3.1e-05 23.7 71.8 0.00023 20.9 4.3 7.6 3 2 3 6 6 6 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EMR64677.1 - 5.4e-05 22.5 31.7 0.034 13.3 2.1 5.8 2 2 3 6 6 6 3 Reovirus sigma C capsid protein Cortex-I_coil PF09304.5 EMR64677.1 - 0.0061 16.5 11.8 0.0061 16.5 8.2 7.6 2 2 6 8 8 8 2 Cortexillin I, coiled coil DUF869 PF05911.6 EMR64677.1 - 0.067 11.4 69.8 0.026 12.8 14.3 4.3 2 1 2 4 4 4 0 Plant protein of unknown function (DUF869) AAA_13 PF13166.1 EMR64677.1 - 0.081 11.3 58.8 0.16 10.3 15.2 4.3 2 1 2 4 4 4 0 AAA domain NPV_P10 PF05531.7 EMR64677.1 - 0.21 11.8 0.2 0.21 11.8 0.1 7.8 6 3 1 9 9 9 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 EMR64677.1 - 0.43 9.5 84.6 0.013 14.5 4.9 6.1 2 2 4 6 6 5 0 Autophagy protein Apg6 HAMP PF00672.20 EMR64677.1 - 0.72 10.0 3.9 6.2 7.0 0.1 2.9 2 0 0 2 2 2 0 HAMP domain DUF3584 PF12128.3 EMR64677.1 - 2.2 5.5 83.9 0.009 13.4 16.7 3.9 1 1 3 4 4 3 0 Protein of unknown function (DUF3584) Filament PF00038.16 EMR64677.1 - 2.4 7.5 78.3 0.048 13.1 22.3 6.0 2 2 4 6 6 6 0 Intermediate filament protein ERM PF00769.14 EMR64677.1 - 6.3 6.2 83.0 0.37 10.2 13.8 5.2 1 1 4 5 5 5 0 Ezrin/radixin/moesin family DUF972 PF06156.8 EMR64677.1 - 6.5 7.1 68.9 0.27 11.5 2.9 9.0 3 3 6 9 9 9 0 Protein of unknown function (DUF972) GAS PF13851.1 EMR64677.1 - 6.8 5.8 83.8 0.016 14.3 3.4 7.4 2 2 5 7 7 7 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 EMR64677.1 - 9.9 5.0 62.3 0.2 10.5 4.8 5.2 2 2 3 5 5 4 0 UV radiation resistance protein and autophagy-related subunit 14 DHDPS PF00701.17 EMR64678.1 - 4.5e-34 117.3 0.0 2.2e-16 59.3 0.0 2.0 1 1 1 2 2 2 2 Dihydrodipicolinate synthetase family Acetyltransf_2 PF00797.12 EMR64679.1 - 9.5e-42 143.2 4.0 1.8e-36 125.9 1.3 3.0 2 1 0 2 2 2 2 N-acetyltransferase Peptidase_C71 PF12386.3 EMR64679.1 - 0.027 13.9 0.1 0.071 12.5 0.1 1.6 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei eIF3_N PF09440.5 EMR64680.1 - 5.4e-45 152.8 1.4 1.1e-44 151.7 1.0 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EMR64680.1 - 1.7e-11 44.3 0.5 3.9e-11 43.1 0.1 1.9 2 0 0 2 2 2 1 PCI domain DDRGK PF09756.4 EMR64680.1 - 0.039 13.3 1.3 1 8.7 0.2 2.6 2 0 0 2 2 2 0 DDRGK domain XhlA PF10779.4 EMR64680.1 - 0.28 11.1 3.0 1.8 8.5 0.0 2.9 2 1 1 3 3 3 0 Haemolysin XhlA FAD_binding_4 PF01565.18 EMR64682.1 - 2.6e-18 65.8 0.5 5e-18 64.9 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR64682.1 - 7.9e-13 48.0 0.2 1.7e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EMR64682.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Methyltransf_2 PF00891.13 EMR64683.1 - 4e-29 101.4 0.0 5.9e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EMR64683.1 - 0.00011 22.7 0.0 0.00024 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR64683.1 - 0.014 14.9 0.0 0.035 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NmrA PF05368.8 EMR64684.1 - 5.1e-18 65.1 0.0 6.8e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR64684.1 - 1.6e-09 38.0 0.0 2.5e-09 37.3 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR64684.1 - 1.5e-05 24.5 0.1 0.00064 19.2 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMR64684.1 - 0.0016 18.3 0.1 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR64684.1 - 0.043 13.4 0.1 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 KR domain Methyltransf_2 PF00891.13 EMR64685.1 - 5.2e-26 91.3 0.0 7.5e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase adh_short PF00106.20 EMR64686.1 - 7.2e-21 74.8 0.0 9.2e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR64686.1 - 1.5e-19 70.7 0.0 1.9e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EMR64686.1 - 0.00045 19.4 0.0 0.0007 18.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EMR64686.1 - 0.00046 19.9 0.0 0.00071 19.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR64686.1 - 0.0014 18.7 0.0 0.0026 17.8 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR64686.1 - 0.0028 17.1 0.0 0.004 16.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMR64686.1 - 0.0046 15.8 0.0 0.01 14.7 0.0 1.6 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.12 EMR64686.1 - 0.018 15.4 0.0 0.034 14.5 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CFEM PF05730.6 EMR64687.1 - 4.2e-14 52.0 11.3 6.1e-14 51.5 7.8 1.2 1 0 0 1 1 1 1 CFEM domain Colicin_C PF12106.3 EMR64687.1 - 0.091 12.3 0.9 0.89 9.1 0.0 2.3 2 0 0 2 2 2 0 Colicin C terminal ribonuclease domain TIL PF01826.12 EMR64687.1 - 1.2 9.2 5.7 1.3 9.2 3.2 1.6 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Trypsin_2 PF13365.1 EMR64688.1 - 0.0016 18.3 0.0 0.0021 18.0 0.0 1.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain 2-Hacid_dh_C PF02826.14 EMR64689.1 - 5.4e-48 162.4 0.1 8.6e-48 161.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMR64689.1 - 6.4e-07 28.9 0.0 9.5e-07 28.3 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMR64689.1 - 5.3e-05 23.1 0.1 0.00015 21.6 0.0 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sugar_tr PF00083.19 EMR64690.1 - 6.1e-77 259.1 19.3 6.9e-77 258.9 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR64690.1 - 1.4e-14 53.6 32.2 2.7e-08 32.9 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-LITAF-like PF10601.4 EMR64690.1 - 0.043 13.6 0.3 0.19 11.6 0.2 2.1 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain TPR_11 PF13414.1 EMR64691.1 - 1e-37 127.6 25.8 7.1e-08 31.9 0.4 11.7 9 2 3 12 12 12 9 TPR repeat TPR_2 PF07719.12 EMR64691.1 - 1.1e-26 90.5 27.4 0.0011 18.7 0.0 14.2 14 0 0 14 14 13 8 Tetratricopeptide repeat TPR_12 PF13424.1 EMR64691.1 - 3.3e-26 91.0 38.8 9e-06 25.5 0.0 12.2 6 4 6 13 13 13 9 Tetratricopeptide repeat TPR_16 PF13432.1 EMR64691.1 - 4.6e-26 90.8 35.2 3.3e-05 24.4 0.1 11.7 11 2 2 13 13 11 6 Tetratricopeptide repeat TPR_1 PF00515.23 EMR64691.1 - 1.5e-24 84.5 20.2 0.00066 19.1 0.0 13.3 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_14 PF13428.1 EMR64691.1 - 1.2e-21 75.2 25.0 0.023 15.3 0.0 13.1 11 4 2 13 13 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 EMR64691.1 - 1e-19 70.5 14.6 0.017 15.4 0.0 9.3 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 EMR64691.1 - 3.2e-18 64.3 9.6 0.0045 17.0 0.0 13.2 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMR64691.1 - 4.7e-14 51.0 25.9 0.011 15.4 0.0 11.9 13 1 1 14 14 13 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMR64691.1 - 1.2e-11 43.4 22.2 0.023 14.4 0.0 11.7 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_6 PF13174.1 EMR64691.1 - 1.7e-06 28.0 27.2 0.15 12.5 0.0 12.4 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMR64691.1 - 2.2e-06 27.4 8.4 1.8 8.4 0.0 6.3 4 2 2 6 6 6 3 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 EMR64691.1 - 0.0028 16.5 0.1 0.013 14.3 0.0 2.0 2 0 0 2 2 2 1 Coatomer WD associated region TPR_10 PF13374.1 EMR64691.1 - 0.032 14.1 8.9 77 3.4 0.1 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat ChAPs PF09295.5 EMR64691.1 - 0.057 12.1 0.4 15 4.2 0.0 3.6 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Foie-gras_1 PF11817.3 EMR64691.1 - 0.25 10.7 5.6 0.11 11.9 0.3 3.0 3 1 1 4 4 4 0 Foie gras liver health family 1 DUF2225 PF09986.4 EMR64691.1 - 0.35 10.3 5.9 2.9 7.2 0.0 4.5 4 2 2 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2225) Glyco_hydro_43 PF04616.9 EMR64692.1 - 1.1e-51 175.6 1.3 1.3e-51 175.4 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBS PF00571.23 EMR64693.1 - 1.2e-41 140.1 7.8 1.6e-10 40.5 0.0 5.4 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EMR64693.1 - 2.1e-08 33.6 0.1 6.3e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 PB1 domain Myc_N PF01056.13 EMR64693.1 - 0.057 12.5 2.2 0.15 11.2 1.5 1.6 1 0 0 1 1 1 0 Myc amino-terminal region Pkinase PF00069.20 EMR64694.1 - 8.4e-60 202.0 0.0 1.3e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64694.1 - 8.7e-43 146.2 0.0 1.2e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR64694.1 - 4.6e-09 35.6 0.0 2.7e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMR64694.1 - 0.0028 16.7 0.0 0.0049 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1843 PF08898.5 EMR64694.1 - 0.034 14.1 0.2 6 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) APH PF01636.18 EMR64694.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sulfate_transp PF00916.15 EMR64695.1 - 2.1e-74 250.0 12.6 2.1e-74 250.0 8.8 1.5 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMR64695.1 - 9.2e-28 95.7 5.6 9.2e-28 95.7 3.9 4.3 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMR64695.1 - 4e-09 35.8 0.0 8.2e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain Epimerase PF01370.16 EMR64696.1 - 3.3e-23 82.3 0.0 4.4e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR64696.1 - 1.2e-10 40.5 0.0 1.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMR64696.1 - 7.7e-06 26.0 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMR64696.1 - 8.8e-06 24.8 0.1 0.00046 19.1 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EMR64696.1 - 2.2e-05 23.4 0.0 3.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EMR64696.1 - 4.4e-05 23.4 0.0 7.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR64696.1 - 0.0004 20.0 0.0 0.00071 19.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EMR64696.1 - 0.003 16.5 0.0 0.0042 16.1 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 EMR64696.1 - 0.005 16.1 0.0 0.015 14.5 0.0 1.7 2 1 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EMR64696.1 - 0.0089 14.9 0.0 0.078 11.8 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 EMR64696.1 - 0.024 14.4 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain zf-MYND PF01753.13 EMR64697.1 - 1e-09 38.1 15.4 2.1e-09 37.1 10.7 1.6 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EMR64697.1 - 0.17 11.1 3.2 0.41 9.9 2.2 1.6 1 0 0 1 1 1 0 Life-span regulatory factor Ribosomal_S2 PF00318.15 EMR64698.1 - 1.9e-48 164.5 0.0 5.9e-48 162.8 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S2 Bac_DNA_binding PF00216.16 EMR64698.1 - 0.041 13.8 0.3 0.087 12.8 0.2 1.5 1 0 0 1 1 1 0 Bacterial DNA-binding protein Aldo_ket_red PF00248.16 EMR64699.1 - 6.4e-66 222.0 0.0 7.6e-66 221.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TRI9 PF08195.6 EMR64699.1 - 0.032 13.8 0.1 0.058 13.0 0.1 1.4 1 0 0 1 1 1 0 TRI9 protein zf-H2C2_2 PF13465.1 EMR64700.1 - 8.5e-10 38.4 11.7 0.00013 22.0 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EMR64700.1 - 9.4e-10 38.2 22.0 4.6e-05 23.5 3.3 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR64700.1 - 3.6e-05 23.7 16.3 0.054 13.8 0.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 EMR64700.1 - 0.36 11.1 7.1 5.8 7.2 1.6 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMR64700.1 - 1.1 9.2 10.6 0.13 12.1 0.3 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger BNR_2 PF13088.1 EMR64701.1 - 4.1e-13 49.2 0.0 4.6e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 EMR64701.1 - 0.026 14.3 0.3 0.072 12.9 0.2 1.8 1 0 0 1 1 1 0 BNR/Asp-box repeat Imm17 PF15591.1 EMR64701.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 17 Fringe PF02434.11 EMR64702.1 - 1.9e-07 30.5 0.0 7.9e-05 21.9 0.1 3.0 2 1 0 2 2 2 1 Fringe-like Methyltransf_2 PF00891.13 EMR64702.1 - 0.0032 16.7 0.0 0.0055 15.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EMR64702.1 - 0.011 15.5 0.1 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain PAN_4 PF14295.1 EMR64702.1 - 0.015 15.0 0.4 0.039 13.6 0.3 1.7 1 0 0 1 1 1 0 PAN domain Put_DNA-bind_N PF06971.8 EMR64702.1 - 0.1 12.4 0.2 0.5 10.1 0.0 2.2 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus FMN_dh PF01070.13 EMR64703.1 - 2e-96 322.9 0.0 2.3e-96 322.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EMR64703.1 - 0.00017 20.6 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EMR64703.1 - 0.00098 18.0 1.2 0.0054 15.6 0.2 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EMR64703.1 - 0.007 15.5 0.1 0.047 12.8 0.0 2.0 1 1 1 2 2 2 1 Nitronate monooxygenase GST_C PF00043.20 EMR64704.1 - 8.6e-16 57.7 0.0 1.8e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMR64704.1 - 4.5e-13 49.1 0.0 2.9e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMR64704.1 - 5.5e-11 42.5 0.1 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMR64704.1 - 2.8e-10 40.0 0.1 7e-10 38.7 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR64704.1 - 2.5e-08 33.6 0.0 4.7e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR64704.1 - 1.2e-07 32.1 0.1 2.1e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FadA PF09403.5 EMR64705.1 - 0.017 15.1 0.6 0.017 15.1 0.4 5.5 4 1 2 7 7 7 0 Adhesion protein FadA Reo_sigmaC PF04582.7 EMR64705.1 - 0.018 14.2 32.6 0.061 12.4 0.0 4.9 2 2 3 5 5 5 0 Reovirus sigma C capsid protein MinE PF03776.9 EMR64705.1 - 0.032 13.7 4.9 1.1 8.8 0.1 3.5 3 0 0 3 3 3 0 Septum formation topological specificity factor MinE CENP-F_leu_zip PF10473.4 EMR64705.1 - 4.1 7.2 71.1 0.21 11.4 1.5 6.2 3 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Amidase PF01425.16 EMR64706.1 - 3.9e-84 283.0 3.3 2.3e-57 194.8 0.0 3.1 2 2 0 2 2 2 2 Amidase CAP_N PF01213.14 EMR64707.1 - 0.36 10.0 0.0 0.36 10.0 0.0 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Sec10 PF07393.6 EMR64708.1 - 4.5e-217 722.6 0.2 5.3e-217 722.4 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Cupin_8 PF13621.1 EMR64709.1 - 8e-32 110.6 0.0 1.3e-31 110.0 0.0 1.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EMR64709.1 - 5.8e-11 42.1 0.0 3.5e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 EMR64709.1 - 9.4e-05 22.6 0.0 0.0045 17.2 0.0 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EMR64709.1 - 0.0074 15.7 0.0 0.044 13.2 0.0 2.1 2 0 0 2 2 2 1 Cupin domain Lactonase PF10282.4 EMR64711.1 - 0.0011 18.0 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Methyltransf_2 PF00891.13 EMR64712.1 - 2.3e-26 92.4 0.0 3.3e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase adh_short PF00106.20 EMR64713.1 - 4.3e-15 56.0 0.1 7.7e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR64713.1 - 0.00011 21.8 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR64713.1 - 0.00061 19.2 0.0 0.0025 17.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMR64713.1 - 0.00063 19.5 0.0 0.0014 18.4 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EMR64713.1 - 0.0032 17.2 0.2 0.013 15.2 0.1 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EMR64713.1 - 0.0057 16.6 0.2 0.01 15.8 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding EHN PF06441.7 EMR64714.1 - 1.2e-28 99.2 0.1 2.4e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EMR64714.1 - 4.1e-05 23.5 0.1 0.00029 20.7 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.20 EMR64715.1 - 1.7e-26 93.1 7.0 2.3e-26 92.6 4.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR64715.1 - 9.7e-15 54.6 3.1 1.4e-14 54.1 2.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR64715.1 - 3.7e-11 43.2 0.2 5e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR64715.1 - 1.9e-06 27.5 0.2 3.2e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMR64715.1 - 0.0039 16.9 0.1 0.01 15.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EMR64715.1 - 0.016 14.1 0.2 0.02 13.7 0.2 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EMR64715.1 - 0.027 14.5 0.7 0.093 12.8 0.5 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DFP PF04127.10 EMR64715.1 - 0.043 13.4 0.8 0.15 11.6 0.5 1.8 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Amidase PF01425.16 EMR64716.1 - 2.9e-63 214.2 0.0 4.5e-49 167.4 0.0 3.0 1 1 1 2 2 2 2 Amidase Fumble PF03630.9 EMR64717.1 - 8.8e-128 425.9 0.0 1.3e-126 422.0 0.0 2.4 1 1 0 1 1 1 1 Fumble Ran_BP1 PF00638.13 EMR64718.1 - 8.4e-51 171.1 0.3 1.5e-50 170.3 0.2 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EMR64718.1 - 0.0015 18.2 0.0 0.0058 16.3 0.0 1.8 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 EMR64718.1 - 0.068 12.7 0.6 0.12 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) Phosducin PF02114.11 EMR64721.1 - 1.1e-11 44.0 0.1 3.9e-10 38.9 0.0 2.3 1 1 1 2 2 2 2 Phosducin DUF2235 PF09994.4 EMR64721.1 - 0.039 13.3 0.2 0.054 12.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF4211 PF13926.1 EMR64723.1 - 6.9e-36 122.9 1.2 1e-34 119.1 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) L51_S25_CI-B8 PF05047.11 EMR64724.1 - 1.1e-14 53.9 0.1 1.5e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.3 EMR64725.1 - 2.4e-28 98.3 1.7 3.8e-28 97.6 1.2 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EMR64725.1 - 1.3e-09 37.5 0.1 9.9e-09 34.7 0.1 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR64725.1 - 3.5e-07 30.1 0.0 7.8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR64725.1 - 0.07 12.9 0.5 0.89 9.4 0.3 2.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.15 EMR64726.1 - 7.4e-21 73.9 0.0 1.2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 zf-Tim10_DDP PF02953.10 EMR64727.1 - 5e-20 70.5 2.3 5e-20 70.5 1.6 1.4 2 0 0 2 2 2 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EMR64727.1 - 0.0018 17.7 1.3 0.0053 16.2 0.9 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) FliT PF05400.8 EMR64727.1 - 0.28 11.6 4.0 0.83 10.1 2.2 1.9 1 1 1 2 2 2 0 Flagellar protein FliT CCDC144C PF14915.1 EMR64727.1 - 0.46 9.3 7.2 0.053 12.4 2.0 1.5 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region IGPS PF00218.16 EMR64728.1 - 4.1e-95 317.6 0.0 6.6e-95 316.9 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 EMR64728.1 - 8.2e-51 172.1 0.0 1.7e-50 171.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.17 EMR64728.1 - 4.5e-42 143.8 0.0 1.5e-38 132.3 0.0 2.6 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 EMR64728.1 - 2.2e-05 24.0 0.0 5.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 FMN_dh PF01070.13 EMR64728.1 - 0.0065 15.3 0.5 0.029 13.2 0.1 2.1 1 1 1 2 2 2 1 FMN-dependent dehydrogenase QRPTase_C PF01729.14 EMR64728.1 - 0.11 12.0 0.1 0.11 12.0 0.1 2.6 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain TIM PF00121.13 EMR64729.1 - 1.7e-86 289.2 0.3 1.9e-86 289.0 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF3837 PF12939.2 EMR64729.1 - 0.0045 16.9 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3837) CutC PF03932.9 EMR64729.1 - 0.023 13.9 0.0 0.046 12.9 0.0 1.4 1 1 0 1 1 1 0 CutC family DLIC PF05783.6 EMR64730.1 - 2.2e-23 82.6 0.0 4.6e-21 75.0 0.0 2.5 3 0 0 3 3 3 2 Dynein light intermediate chain (DLIC) FAD_binding_7 PF03441.9 EMR64732.1 - 7.2e-55 186.1 0.3 1.1e-54 185.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EMR64732.1 - 3.5e-06 26.8 0.0 6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Thioredox_DsbH PF03190.10 EMR64734.1 - 9.7e-55 184.7 0.0 1.6e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EMR64734.1 - 2.6e-06 27.3 0.0 5.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like DUF468 PF04318.7 EMR64734.1 - 0.0083 16.6 0.1 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF468) DUF1680 PF07944.7 EMR64734.1 - 0.049 11.9 0.2 0.088 11.0 0.1 1.3 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) Mucin PF01456.12 EMR64734.1 - 8.1 6.2 25.1 6 6.6 9.0 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein AMIN PF11741.3 EMR64735.1 - 0.059 13.3 0.3 0.14 12.0 0.2 1.7 2 1 0 2 2 2 0 AMIN domain TRAM_LAG1_CLN8 PF03798.11 EMR64736.1 - 8.7e-34 116.8 16.0 1.4e-33 116.1 11.1 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EMR64736.1 - 1.2e-18 66.3 0.4 3.8e-18 64.7 0.3 1.9 1 0 0 1 1 1 1 TRAM1-like protein RelA_SpoT PF04607.12 EMR64737.1 - 1.1e-09 38.3 0.0 2.6e-09 37.0 0.0 1.6 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins Peptidase_S10 PF00450.17 EMR64738.1 - 7.9e-80 269.0 0.0 1.1e-79 268.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RRM_1 PF00076.17 EMR64739.1 - 1.2e-13 50.5 0.0 9.5e-13 47.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR64739.1 - 7.7e-08 32.2 0.0 2.6e-07 30.5 0.0 1.9 1 1 1 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR64739.1 - 0.00025 20.8 0.0 0.00097 18.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bax1-I PF01027.15 EMR64740.1 - 1.8e-49 168.1 25.3 2.2e-49 167.8 17.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Septin PF00735.13 EMR64741.1 - 1e-107 359.3 0.1 2.2e-107 358.2 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EMR64741.1 - 0.0003 20.7 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMR64741.1 - 0.0028 17.5 3.8 0.91 9.3 0.0 3.0 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EMR64741.1 - 0.0029 16.7 0.2 0.0089 15.2 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMR64741.1 - 0.012 15.8 0.1 0.043 13.9 0.0 2.0 2 2 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EMR64741.1 - 0.013 16.2 3.6 0.067 14.0 0.1 2.8 2 2 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EMR64741.1 - 0.033 13.6 0.1 0.11 11.9 0.1 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EMR64741.1 - 0.045 13.6 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EMR64741.1 - 0.052 14.0 0.3 0.14 12.6 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EMR64741.1 - 0.17 11.3 0.0 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF3653 PF12375.3 EMR64741.1 - 0.64 10.2 4.2 17 5.7 1.9 2.9 2 1 0 2 2 2 0 Phage protein V_ATPase_I PF01496.14 EMR64741.1 - 4.4 5.0 4.7 7 4.3 3.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C2H2 PF00096.21 EMR64742.1 - 3.3e-08 33.3 18.6 0.0093 16.2 1.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR64742.1 - 4.5e-07 29.7 16.7 0.0016 18.6 0.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 EMR64742.1 - 0.033 14.3 4.5 0.033 14.3 3.1 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EMR64742.1 - 0.18 12.1 26.8 0.88 9.9 1.3 4.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMR64742.1 - 1.6 8.9 9.3 4.6 7.5 1.3 3.9 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PX PF00787.19 EMR64744.1 - 5.7e-19 67.9 0.2 1.4e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EMR64744.1 - 0.00064 19.0 0.0 0.00089 18.5 0.0 1.1 1 0 0 1 1 1 1 Vps5 C terminal like DUF3140 PF11338.3 EMR64744.1 - 0.019 15.0 0.3 0.046 13.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) PH PF00169.24 EMR64745.1 - 6e-10 39.2 0.0 1.6e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMR64745.1 - 2.3e-07 31.0 0.1 5.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EMR64745.1 - 0.0017 18.3 0.0 0.0075 16.3 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain DUF3409 PF11889.3 EMR64745.1 - 0.0084 15.7 0.5 0.021 14.4 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3409) Gastrin PF00918.12 EMR64745.1 - 0.065 14.0 0.7 0.33 11.7 0.0 2.5 3 0 0 3 3 3 0 Gastrin/cholecystokinin family zf-MIZ PF02891.15 EMR64746.1 - 1.9e-09 36.9 5.6 1.5e-07 30.8 0.1 2.3 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EMR64746.1 - 0.00078 18.9 1.6 0.0024 17.3 1.1 1.9 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Peptidase_S10 PF00450.17 EMR64747.1 - 5.2e-113 378.3 0.1 6.4e-113 378.0 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Act-Frag_cataly PF09192.5 EMR64747.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic p450 PF00067.17 EMR64748.1 - 1.3e-29 103.0 0.0 1.5e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EMR64749.1 - 9.2e-14 51.2 2.9 7.6e-12 44.9 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 EMR64749.1 - 0.00023 20.0 0.0 0.0004 19.2 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 EMR64749.1 - 0.00065 19.6 0.6 0.0026 17.7 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMR64749.1 - 0.0055 16.5 1.8 0.0092 15.7 0.1 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EMR64749.1 - 0.0073 15.2 0.7 0.026 13.4 0.1 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMR64749.1 - 0.016 13.8 0.2 1.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.22 EMR64749.1 - 0.03 14.7 0.1 0.085 13.2 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 EMR64750.1 - 5.9e-10 39.4 0.1 7.7e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR64750.1 - 1.1e-06 28.2 0.0 1.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR64750.1 - 2.7e-06 26.4 0.0 0.005 15.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EMR64750.1 - 3.8e-05 22.5 0.0 5.3e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EMR64750.1 - 0.00058 19.7 0.1 0.0016 18.3 0.1 1.8 1 1 1 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 EMR64750.1 - 0.0086 15.3 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family But2 PF09792.4 EMR64751.1 - 0.017 14.9 0.2 0.03 14.0 0.1 1.5 1 1 1 2 2 2 0 Ubiquitin 3 binding protein But2 C-terminal domain PhyH PF05721.8 EMR64752.1 - 5.8e-12 46.0 0.0 7.9e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.11 EMR64752.1 - 0.031 13.9 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family DNA_pol_A_exo1 PF01612.15 EMR64753.1 - 5.3e-09 35.7 0.0 6.8e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 3'-5' exonuclease Pyr_redox_2 PF07992.9 EMR64754.1 - 3.2e-12 46.7 0.2 1.2e-11 44.9 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR64754.1 - 4.2e-07 29.1 2.0 9.9e-06 24.6 0.2 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMR64754.1 - 2.4e-06 27.3 0.1 0.029 14.1 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EMR64754.1 - 4.6e-05 22.4 0.0 9.8e-05 21.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMR64754.1 - 4.8e-05 23.3 0.1 9.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EMR64754.1 - 4.9e-05 21.9 0.1 0.00022 19.8 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EMR64754.1 - 0.00013 20.9 0.1 0.0084 15.0 0.0 2.3 1 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EMR64754.1 - 0.00052 19.1 0.2 0.0008 18.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EMR64754.1 - 0.00099 19.2 0.0 0.071 13.1 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR64754.1 - 0.0026 16.8 0.1 0.0043 16.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EMR64754.1 - 0.0078 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMR64754.1 - 0.014 14.3 0.0 0.074 11.9 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EMR64754.1 - 0.02 13.5 0.2 0.89 8.0 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 EMR64754.1 - 0.028 13.7 0.1 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 EMR64754.1 - 0.11 12.9 0.1 0.53 10.7 0.0 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RCC1 PF00415.13 EMR64755.1 - 3.1e-50 168.1 14.7 5.1e-09 36.1 0.0 8.5 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMR64755.1 - 6.2e-30 102.1 39.1 2.7e-08 33.1 1.8 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Glyco_hydro_76 PF03663.9 EMR64756.1 - 4.9e-148 493.4 12.6 6.2e-148 493.1 8.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EMR64756.1 - 0.00042 19.4 4.5 0.023 13.7 0.0 2.8 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 adh_short PF00106.20 EMR64758.1 - 1.8e-14 53.9 0.1 3.1e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR64758.1 - 3.7e-07 29.9 0.0 7.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 EMR64759.1 - 2e-20 72.8 12.2 5.3e-20 71.4 8.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1430 PF07242.6 EMR64759.1 - 0.08 13.0 0.5 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Phage_holin_5 PF06946.6 EMR64759.1 - 0.41 10.8 2.8 0.51 10.5 0.1 2.3 1 1 1 2 2 2 0 Phage holin Peptidase_S15 PF02129.13 EMR64760.1 - 3.4e-37 128.3 4.9 1.6e-35 122.8 0.4 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EMR64760.1 - 2.3e-17 63.6 0.0 4e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EMR64760.1 - 0.0066 16.3 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pyr_redox_2 PF07992.9 EMR64761.1 - 2.1e-05 24.4 0.0 2.3e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMR64761.1 - 0.00019 20.5 0.1 0.00026 20.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EMR64761.1 - 0.0027 16.6 0.2 0.0035 16.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR64761.1 - 0.0034 16.3 0.6 0.004 16.0 0.4 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR64761.1 - 0.0059 16.5 0.1 0.022 14.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMR64761.1 - 0.0089 14.9 0.1 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EMR64761.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EMR64761.1 - 0.012 15.4 0.6 0.019 14.7 0.3 1.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EMR64761.1 - 0.034 12.6 0.1 0.047 12.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 EMR64761.1 - 0.09 11.3 0.5 0.13 10.8 0.1 1.4 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.13 EMR64761.1 - 0.1 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Ank_2 PF12796.2 EMR64762.1 - 8.3e-06 26.0 0.0 0.0068 16.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMR64762.1 - 0.018 14.8 0.0 0.54 10.1 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.1 EMR64762.1 - 0.053 14.0 0.0 6.7 7.3 0.0 3.5 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Mic1 PF07035.7 EMR64762.1 - 0.14 11.4 0.0 0.42 9.9 0.0 1.7 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like Y_phosphatase2 PF03162.8 EMR64764.1 - 3.2e-45 153.4 0.0 4e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EMR64764.1 - 6.5e-10 39.4 0.0 2.4e-09 37.6 0.0 1.7 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EMR64764.1 - 0.00014 21.4 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMR64764.1 - 0.00063 19.1 0.0 0.00098 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DAO PF01266.19 EMR64765.1 - 1.9e-14 53.3 0.0 2.1e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Frataxin_Cyay PF01491.11 EMR64766.1 - 0.22 11.3 1.3 0.24 11.2 0.9 1.2 1 0 0 1 1 1 0 Frataxin-like domain Glyoxalase PF00903.20 EMR64767.1 - 1.8e-10 40.8 0.0 5.2e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMR64767.1 - 2.2e-10 41.0 0.0 3.7e-09 37.1 0.0 2.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EMR64767.1 - 4.3e-07 29.9 0.0 0.00033 20.6 0.0 2.0 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3767 PF12597.3 EMR64768.1 - 0.045 13.4 0.2 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) OPT PF03169.10 EMR64771.1 - 6.3e-125 417.9 33.3 1e-123 414.0 23.1 1.9 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Sigma70_r3 PF04539.11 EMR64771.1 - 0.17 11.7 0.6 0.56 10.1 0.4 1.8 2 0 0 2 2 2 0 Sigma-70 region 3 TMEM117 PF15113.1 EMR64772.1 - 0.056 12.0 0.3 0.11 11.0 0.0 1.5 2 0 0 2 2 2 0 TMEM117 protein family Med13_C PF06333.7 EMR64772.1 - 2.9 6.3 10.5 4.5 5.6 7.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal PBP_sp32 PF07222.7 EMR64772.1 - 3.6 6.7 9.9 6.4 5.8 6.8 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Daxx PF03344.10 EMR64772.1 - 5.3 5.4 25.7 0.011 14.2 10.0 1.9 2 0 0 2 2 2 0 Daxx Family PKD PF00801.15 EMR64774.1 - 0.0023 17.6 2.0 0.0062 16.2 0.6 2.3 2 0 0 2 2 2 1 PKD domain Tannase PF07519.6 EMR64774.1 - 0.0055 15.4 1.4 0.28 9.8 0.0 2.4 2 0 0 2 2 2 2 Tannase and feruloyl esterase DsrH PF04077.7 EMR64776.1 - 0.0069 16.0 2.7 0.0097 15.5 0.2 2.4 3 0 0 3 3 3 1 DsrH like protein DUF1640 PF07798.6 EMR64776.1 - 0.028 14.4 12.5 0.43 10.6 8.6 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1664 PF07889.7 EMR64776.1 - 7.1 6.4 10.1 0.88 9.3 0.1 3.4 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) GMC_oxred_N PF00732.14 EMR64778.1 - 4e-55 187.0 0.0 5.7e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR64778.1 - 5.1e-30 104.6 0.0 2.3e-29 102.5 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EMR64778.1 - 6.9e-09 35.0 0.2 6.8e-05 21.9 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMR64778.1 - 2.4e-05 23.4 0.0 3.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMR64778.1 - 2.5e-05 24.2 0.0 6.8e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR64778.1 - 0.00017 21.7 0.0 0.22 11.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR64778.1 - 0.0021 16.9 0.4 0.078 11.8 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EMR64778.1 - 0.0055 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EMR64778.1 - 0.015 15.2 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR64778.1 - 0.089 11.2 0.0 0.16 10.4 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 EMR64778.1 - 0.11 11.4 0.1 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EMR64778.1 - 0.15 11.8 0.2 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF4282 PF14110.1 EMR64780.1 - 0.018 15.2 0.8 0.018 15.2 0.5 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF4282) DUF1772 PF08592.6 EMR64780.1 - 2 8.1 6.0 10 5.8 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DNA_pol_A_exo1 PF01612.15 EMR64781.1 - 7.7e-40 136.2 0.2 1.6e-39 135.2 0.1 1.6 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EMR64781.1 - 1.2e-23 83.2 1.1 4.1e-23 81.5 0.8 2.0 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 EMR64781.1 - 3.5e-12 45.8 0.0 1e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 HRDC domain UPF0233 PF06781.7 EMR64782.1 - 0.0035 16.9 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0233) Abhydrolase_6 PF12697.2 EMR64783.1 - 9.9e-24 84.4 0.1 1.3e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR64783.1 - 7e-12 45.3 0.0 9.8e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR64783.1 - 6.5e-08 32.4 0.0 7.3e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EMR64783.1 - 2.3e-05 24.7 0.0 3.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 EMR64783.1 - 0.00039 20.2 0.0 0.00069 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EMR64783.1 - 0.11 11.9 0.1 4.1 6.7 0.1 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DUF3237 PF11578.3 EMR64784.1 - 1.6e-10 40.4 0.0 1.9e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) CdhD PF03599.11 EMR64784.1 - 0.13 10.6 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit DAO PF01266.19 EMR64785.1 - 9e-07 28.1 0.5 3.6e-05 22.8 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 EMR64785.1 - 2.1e-06 27.1 0.0 2.4e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 EMR64785.1 - 3.2e-06 27.1 0.2 0.00014 21.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR64785.1 - 2.7e-05 23.1 0.4 4.8e-05 22.3 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EMR64785.1 - 0.0002 21.3 0.9 0.00038 20.4 0.6 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMR64785.1 - 0.00061 18.8 0.1 0.00087 18.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMR64785.1 - 0.0051 16.8 0.1 0.035 14.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMR64785.1 - 0.0053 15.4 0.3 0.0058 15.3 0.2 1.1 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.9 EMR64785.1 - 0.011 14.1 0.1 0.011 14.1 0.1 1.4 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EMR64785.1 - 0.017 14.2 0.1 0.025 13.6 0.1 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EMR64785.1 - 0.039 13.7 0.2 0.039 13.7 0.1 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Inositol_P PF00459.20 EMR64786.1 - 6.2e-63 212.6 0.2 7.2e-63 212.4 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family ADH_N PF08240.7 EMR64787.1 - 2.7e-25 88.2 6.7 3.1e-25 88.0 3.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR64787.1 - 3.2e-17 62.2 0.1 5.1e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EMR64787.1 - 0.0023 17.5 0.2 0.0045 16.6 0.2 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 EMR64787.1 - 0.0029 17.1 0.1 0.0052 16.3 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GTP_EFTU_D2 PF03144.20 EMR64787.1 - 0.004 17.2 0.1 0.012 15.7 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 2-Hacid_dh_C PF02826.14 EMR64787.1 - 0.004 16.3 0.1 0.006 15.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 EMR64787.1 - 0.05 14.4 0.0 0.13 13.1 0.0 1.8 1 1 1 2 2 2 0 Zinc-binding dehydrogenase GMC_oxred_C PF05199.8 EMR64788.1 - 1e-34 119.9 0.0 2e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR64788.1 - 2.5e-19 69.5 0.0 3.3e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.11 EMR64790.1 - 1.1e-32 113.1 51.0 6.2e-31 107.3 35.3 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR64790.1 - 6.5e-08 31.5 8.7 6.5e-08 31.5 6.0 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter His_Phos_2 PF00328.17 EMR64791.1 - 6.2e-53 180.3 0.0 7.4e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ras PF00071.17 EMR64792.1 - 4.1e-44 149.8 0.0 1.6e-32 112.1 0.0 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 EMR64792.1 - 5.3e-12 46.2 0.0 3.2e-06 27.6 0.0 2.4 1 1 1 2 2 2 2 Miro-like protein Arf PF00025.16 EMR64792.1 - 2.1e-06 27.1 0.0 0.025 13.8 0.0 2.3 1 1 1 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMR64792.1 - 0.0037 16.7 0.0 0.016 14.6 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMR64792.1 - 0.021 14.9 0.0 0.06 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMR64792.1 - 0.052 13.5 0.1 0.12 12.3 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain AAA_2 PF07724.9 EMR64793.1 - 7.4e-47 159.4 0.0 3e-45 154.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EMR64793.1 - 5.1e-28 97.9 0.3 4.6e-15 55.9 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EMR64793.1 - 6.2e-24 83.7 0.6 2.8e-23 81.6 0.4 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EMR64793.1 - 2e-16 60.5 9.5 6.5e-06 26.2 0.0 6.0 4 2 1 7 7 6 2 AAA ATPase domain AAA_5 PF07728.9 EMR64793.1 - 1.9e-15 56.8 0.2 1.5e-09 37.7 0.0 3.2 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMR64793.1 - 9.2e-13 48.4 0.0 0.00014 22.0 0.0 3.8 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EMR64793.1 - 8e-09 35.1 0.0 3.1e-05 23.4 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 EMR64793.1 - 1e-08 36.0 4.0 0.013 16.2 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EMR64793.1 - 2.2e-07 30.5 0.2 0.029 14.1 0.1 3.2 3 0 0 3 3 2 2 Part of AAA domain IstB_IS21 PF01695.12 EMR64793.1 - 4.5e-07 29.4 0.0 0.025 13.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EMR64793.1 - 1.1e-06 29.0 2.6 0.02 15.1 0.0 3.9 4 0 0 4 4 3 2 AAA domain Clp_N PF02861.15 EMR64793.1 - 1.2e-06 28.3 9.2 0.00059 19.7 0.0 4.9 5 0 0 5 5 4 1 Clp amino terminal domain Arch_ATPase PF01637.13 EMR64793.1 - 4.6e-06 26.5 6.5 0.0096 15.6 0.1 5.0 4 1 0 4 4 4 1 Archaeal ATPase AAA_33 PF13671.1 EMR64793.1 - 8.9e-06 25.6 0.2 0.21 11.4 0.0 3.6 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EMR64793.1 - 2.3e-05 23.6 0.1 0.13 11.4 0.0 3.4 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EMR64793.1 - 2.4e-05 24.3 0.0 0.26 11.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EMR64793.1 - 5.5e-05 23.2 0.0 0.46 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase T2SE PF00437.15 EMR64793.1 - 9.6e-05 21.4 0.1 0.01 14.7 0.0 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 EMR64793.1 - 0.00019 21.1 0.0 0.85 9.3 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 EMR64793.1 - 0.00026 20.8 0.8 0.12 12.2 0.0 3.8 3 1 1 4 4 3 1 Type III restriction enzyme, res subunit AAA_3 PF07726.6 EMR64793.1 - 0.00031 20.3 0.0 2 8.0 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EMR64793.1 - 0.00058 19.3 3.5 1.6 8.0 0.0 4.5 4 1 0 5 5 5 2 AAA domain ABC_tran PF00005.22 EMR64793.1 - 0.0006 20.1 0.4 0.84 9.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_24 PF13479.1 EMR64793.1 - 0.00084 18.9 0.0 1.1 8.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EMR64793.1 - 0.00098 18.6 0.0 0.82 9.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EMR64793.1 - 0.0011 18.2 0.0 0.46 9.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Torsin PF06309.6 EMR64793.1 - 0.0026 17.6 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 Torsin NTPase_1 PF03266.10 EMR64793.1 - 0.0028 17.3 0.0 0.27 10.9 0.0 3.5 3 0 0 3 3 3 1 NTPase AAA_10 PF12846.2 EMR64793.1 - 0.0033 16.8 5.6 0.67 9.3 0.0 5.1 4 2 0 5 5 5 1 AAA-like domain NACHT PF05729.7 EMR64793.1 - 0.0042 16.7 0.0 0.35 10.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.17 EMR64793.1 - 0.014 14.8 0.1 3.9 6.8 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_21 PF13304.1 EMR64793.1 - 0.015 15.2 0.4 2.3 8.1 0.0 3.3 4 0 0 4 4 3 0 AAA domain UPF0079 PF02367.12 EMR64793.1 - 0.033 13.8 0.0 8.7 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 EMR64793.1 - 0.09 12.3 0.0 10 5.5 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein V_ATPase_I PF01496.14 EMR64793.1 - 0.092 10.5 3.0 0.17 9.7 2.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MMR_HSR1 PF01926.18 EMR64793.1 - 0.12 12.3 0.1 3.1 7.7 0.0 3.3 3 1 0 3 3 3 0 50S ribosome-binding GTPase Peptidase_M16 PF00675.15 EMR64793.1 - 0.31 10.7 2.3 15 5.3 0.0 2.8 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Macoilin PF09726.4 EMR64793.1 - 0.39 8.9 11.6 0.64 8.2 8.0 1.2 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 EMR64793.1 - 1.5 8.4 7.6 3.9 7.0 5.2 1.7 1 0 0 1 1 1 0 IncA protein DUF724 PF05266.9 EMR64793.1 - 1.7 8.2 9.3 0.21 11.1 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) AAA_23 PF13476.1 EMR64793.1 - 2.1 8.6 0.0 2.1 8.6 0.0 3.9 3 1 0 3 3 2 0 AAA domain Viral_P18 PF04521.8 EMR64793.1 - 4.6 6.7 6.9 6.1 6.3 0.5 2.5 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Imm49 PF15660.1 EMR64794.1 - 0.086 12.8 0.6 0.086 12.8 0.4 1.8 2 0 0 2 2 2 0 Immunity protein 49 2OG-FeII_Oxy_3 PF13640.1 EMR64794.1 - 0.5 10.9 2.7 1.6 9.3 1.9 1.9 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily zf-C3HC4_3 PF13920.1 EMR64795.1 - 0.0011 18.5 11.6 0.0019 17.7 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EMR64795.1 - 0.0022 17.7 6.7 0.0033 17.1 4.6 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 EMR64795.1 - 0.47 10.5 13.7 0.78 9.8 9.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR64795.1 - 0.6 9.8 13.0 0.95 9.2 9.0 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Peptidase_C50 PF03568.12 EMR64796.1 - 6.2e-105 351.0 0.0 3.4e-104 348.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase family C50 CHAT PF12770.2 EMR64796.1 - 4e-07 29.4 1.9 5.8e-05 22.3 1.3 2.2 1 1 0 1 1 1 1 CHAT domain Mito_fiss_reg PF05308.6 EMR64796.1 - 0.02 14.2 2.8 0.036 13.4 1.9 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EMR64796.1 - 1.4 8.1 3.3 2.5 7.3 2.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NARG2_C PF10505.4 EMR64797.1 - 0.085 12.0 0.1 0.099 11.8 0.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus Mhr1 PF12829.2 EMR64798.1 - 1.1e-23 82.8 0.0 2e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Sulfotransfer_3 PF13469.1 EMR64799.1 - 0.035 15.0 0.0 0.091 13.6 0.0 1.7 1 1 0 1 1 1 0 Sulfotransferase family Fungal_trans PF04082.13 EMR64800.1 - 8.7e-09 34.6 0.0 1.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PI3_PI4_kinase PF00454.22 EMR64801.1 - 3e-31 108.6 0.0 5e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase CBFD_NFYB_HMF PF00808.18 EMR64802.1 - 5.5e-15 55.1 2.0 9.8e-15 54.3 1.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMR64802.1 - 1.2e-07 31.7 0.5 1.8e-07 31.1 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 ORC3_N PF07034.6 EMR64802.1 - 0.012 14.6 1.3 0.014 14.3 0.9 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus DTHCT PF08070.6 EMR64802.1 - 0.23 12.1 5.3 0.13 12.9 1.7 2.0 1 1 0 1 1 1 0 DTHCT (NUC029) region Myc_N PF01056.13 EMR64802.1 - 0.26 10.4 2.5 0.31 10.1 1.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Kri1 PF05178.7 EMR64803.1 - 2.5e-27 95.1 24.0 2.5e-27 95.1 16.6 5.5 5 2 1 6 6 6 1 KRI1-like family Kri1_C PF12936.2 EMR64803.1 - 3.8e-26 90.8 1.8 3.8e-26 90.8 1.2 4.0 3 1 1 4 4 4 1 KRI1-like family C-terminal RQC PF09382.5 EMR64804.1 - 0.039 13.6 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 RQC domain FGGY_C PF02782.11 EMR64805.1 - 3.9e-27 95.1 0.0 7e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Cation_efflux PF01545.16 EMR64805.1 - 2e-23 82.8 0.1 4.4e-23 81.7 0.0 1.6 2 0 0 2 2 2 1 Cation efflux family FGGY_N PF00370.16 EMR64805.1 - 5.8e-18 65.0 0.0 7.7e-13 48.3 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain PIG-X PF08320.7 EMR64806.1 - 1e-64 217.6 0.0 2e-64 216.6 0.0 1.5 2 0 0 2 2 2 1 PIG-X / PBN1 SnoaL_4 PF13577.1 EMR64807.1 - 5e-09 36.1 0.1 7.6e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EMR64807.1 - 0.00067 19.8 0.1 0.00098 19.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) FSH1 PF03959.8 EMR64808.1 - 2.6e-23 82.6 0.0 2.2e-22 79.5 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EMR64808.1 - 0.00012 22.0 0.1 0.00016 21.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_11 PF13414.1 EMR64811.1 - 5.9e-07 29.0 5.7 0.017 14.7 0.6 4.8 3 2 1 4 4 4 3 TPR repeat TPR_16 PF13432.1 EMR64811.1 - 7.2e-05 23.3 7.0 0.44 11.2 0.2 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMR64811.1 - 8.2e-05 22.9 5.4 0.025 15.2 0.0 4.3 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMR64811.1 - 0.00069 19.9 3.7 0.32 11.3 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMR64811.1 - 0.011 15.8 0.6 13 6.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMR64811.1 - 0.026 14.4 5.1 16 5.7 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMR64811.1 - 0.14 12.1 6.1 1.5 8.7 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMR64811.1 - 1.2 8.8 8.1 32 4.3 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Arrestin_N PF00339.24 EMR64812.1 - 6.2e-15 55.3 0.0 8.9e-14 51.5 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EMR64812.1 - 6.1e-13 49.0 0.0 9.9e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EMR64812.1 - 0.034 13.6 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like MraY_sig1 PF10555.4 EMR64813.1 - 0.011 14.9 1.4 65 3.1 0.0 5.0 8 0 0 8 8 8 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Bcl-2 PF00452.14 EMR64813.1 - 0.62 10.2 7.9 11 6.2 0.2 3.5 1 1 3 4 4 4 0 Apoptosis regulator proteins, Bcl-2 family KRTAP PF11759.3 EMR64813.1 - 1.4 9.2 10.2 95 3.3 7.1 2.4 1 1 0 1 1 1 0 Keratin-associated matrix zf-Nse PF11789.3 EMR64814.1 - 3e-20 71.4 0.2 5.3e-20 70.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 EMR64814.1 - 0.0079 15.6 0.2 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 EMR64814.1 - 0.0081 15.8 0.8 0.024 14.3 0.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EMR64814.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tho2 PF11262.3 EMR64814.1 - 0.49 9.3 2.4 1.2 8.1 1.6 1.7 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF3584 PF12128.3 EMR64814.1 - 2.6 5.2 19.8 0.023 12.0 8.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) MR_MLE_C PF13378.1 EMR64815.1 - 3.3e-19 68.9 0.0 1.6e-18 66.6 0.0 2.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EMR64815.1 - 1.7e-13 50.8 0.1 4.9e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EMR64815.1 - 0.00034 20.5 0.0 0.0007 19.5 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 EMR64815.1 - 0.026 13.4 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus PH PF00169.24 EMR64816.1 - 7.5e-06 26.1 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 PH domain EF_assoc_2 PF08356.7 EMR64817.1 - 1.5e-33 114.3 0.0 2.7e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 EF hand associated Miro PF08477.8 EMR64817.1 - 6.9e-26 91.0 0.0 3.2e-19 69.5 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 EMR64817.1 - 1.2e-16 60.5 0.0 1.1e-15 57.4 0.0 2.0 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 EMR64817.1 - 0.00027 20.8 0.0 0.00093 19.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_7 PF13499.1 EMR64817.1 - 0.00031 20.8 0.1 0.00088 19.3 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EMR64817.1 - 0.0033 16.6 0.0 0.01 15.0 0.0 1.8 1 0 0 1 1 1 1 EF hand AAA_24 PF13479.1 EMR64817.1 - 0.0075 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain EF-hand_6 PF13405.1 EMR64817.1 - 0.013 15.3 0.1 0.038 13.8 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain AAA_22 PF13401.1 EMR64817.1 - 0.03 14.4 0.0 0.077 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMR64817.1 - 0.08 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain EF-hand_10 PF14788.1 EMR64817.1 - 0.098 12.3 0.1 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.1 EMR64817.1 - 0.12 11.7 0.1 0.43 10.0 0.0 2.0 2 0 0 2 2 2 0 EF hand MobB PF03205.9 EMR64817.1 - 0.16 11.6 0.1 0.39 10.4 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1772 PF08592.6 EMR64818.1 - 6.3e-05 22.7 1.1 8.4e-05 22.3 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) WD40 PF00400.27 EMR64820.1 - 2e-08 33.7 0.2 4.8e-05 23.0 0.0 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Leptin PF02024.10 EMR64820.1 - 0.025 14.2 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Leptin ECR1_N PF14382.1 EMR64820.1 - 0.039 13.2 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region Clr5 PF14420.1 EMR64821.1 - 3.3e-15 55.7 0.2 4.5e-15 55.2 0.1 1.2 1 0 0 1 1 1 1 Clr5 domain AAA PF00004.24 EMR64822.1 - 7.1e-08 32.7 0.0 2.5e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.7 EMR64822.1 - 0.019 14.4 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Hex_IIIa PF02455.11 EMR64822.1 - 0.99 8.0 11.2 1.4 7.4 7.8 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) peroxidase PF00141.18 EMR64823.1 - 4.6e-49 166.9 0.0 6.6e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase adh_short PF00106.20 EMR64824.1 - 6.5e-12 45.6 0.0 9.5e-11 41.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMR64824.1 - 0.00042 20.3 0.0 0.00073 19.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMR64824.1 - 0.0055 16.3 0.0 0.0095 15.6 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR64824.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EMR64824.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EMR64824.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Acetyltransf_2 PF00797.12 EMR64825.1 - 0.002 17.7 0.0 0.0025 17.4 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase ADH_zinc_N PF00107.21 EMR64826.1 - 3.2e-12 46.1 0.2 5.6e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR64826.1 - 2.1e-07 30.6 0.1 7.4e-07 28.9 0.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Lon_C PF05362.8 EMR64829.1 - 3.5e-64 215.9 0.0 6.2e-64 215.0 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EMR64829.1 - 5.7e-32 111.0 0.0 1.3e-31 109.8 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EMR64829.1 - 9.5e-22 77.6 0.0 2.2e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EMR64829.1 - 1.5e-07 30.9 0.0 4e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EMR64829.1 - 4.3e-07 29.7 0.0 1.1e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMR64829.1 - 1.7e-06 28.0 0.0 5.1e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EMR64829.1 - 1.5e-05 25.1 0.0 0.00044 20.4 0.0 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMR64829.1 - 2.8e-05 23.3 0.0 0.0011 18.0 0.0 3.0 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_PrkA PF08298.6 EMR64829.1 - 3.5e-05 22.6 0.0 7.4e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 EMR64829.1 - 6.3e-05 23.7 0.0 0.00035 21.3 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EMR64829.1 - 0.00012 22.0 1.2 0.0035 17.3 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 EMR64829.1 - 0.004 17.4 0.8 0.026 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ClpB_D2-small PF10431.4 EMR64829.1 - 0.0062 16.4 0.2 0.0062 16.4 0.2 2.6 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_14 PF13173.1 EMR64829.1 - 0.0076 16.1 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 EMR64829.1 - 0.009 15.5 0.1 0.21 11.0 0.0 2.7 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 EMR64829.1 - 0.019 14.6 0.0 0.054 13.1 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SKI PF01202.17 EMR64829.1 - 0.027 14.3 0.2 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase IstB_IS21 PF01695.12 EMR64829.1 - 0.032 13.6 0.0 0.079 12.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 EMR64829.1 - 0.035 13.3 0.0 0.08 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EMR64829.1 - 0.037 14.2 0.0 0.12 12.5 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EMR64829.1 - 0.055 12.8 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EMR64829.1 - 0.079 11.6 2.9 0.85 8.2 0.0 2.7 3 0 0 3 3 3 0 TIP49 C-terminus AAA_33 PF13671.1 EMR64829.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMR64829.1 - 0.42 10.8 4.3 0.59 10.4 0.0 2.7 3 0 0 3 3 2 0 ABC transporter ADH_N PF08240.7 EMR64830.1 - 1.8e-11 43.7 0.0 4.2e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR64830.1 - 4.2e-09 36.0 0.1 7.5e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MutL_C PF08676.6 EMR64831.1 - 5.7e-18 64.9 1.9 5.8e-17 61.6 0.7 2.9 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EMR64831.1 - 1.2e-14 54.1 0.0 6.6e-14 51.7 0.0 2.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EMR64831.1 - 1.9e-12 46.8 0.0 5e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.20 EMR64832.1 - 0.00018 20.7 0.0 0.00034 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain CoA_binding_2 PF13380.1 EMR64834.1 - 2.4e-28 98.6 0.0 3.1e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain MFS_1 PF07690.11 EMR64835.1 - 1.3e-34 119.5 19.0 1.6e-34 119.1 13.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR64835.1 - 4.3e-09 35.4 10.5 5.5e-09 35.1 7.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EMR64835.1 - 1.1e-08 33.8 6.9 1.3e-08 33.5 4.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 EMR64835.1 - 2.6e-06 26.1 8.5 3.2e-06 25.8 5.9 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_2 PF13347.1 EMR64835.1 - 8.6e-06 24.4 2.4 8.6e-06 24.4 1.7 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein COX2-transmemb PF09125.5 EMR64835.1 - 0.13 11.7 2.3 0.18 11.3 0.2 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane Sugar_tr PF00083.19 EMR64836.1 - 3.1e-52 177.6 11.2 3.9e-52 177.3 7.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR64836.1 - 3.7e-13 48.9 16.0 3.7e-13 48.9 11.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Imm16 PF15565.1 EMR64836.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 16 MFS_1 PF07690.11 EMR64837.1 - 2.5e-09 36.3 18.2 2.5e-09 36.3 12.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EMR64838.1 - 7.1e-49 166.5 0.0 2.9e-48 164.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DLH PF01738.13 EMR64839.1 - 3.9e-22 78.5 0.0 4.6e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMR64839.1 - 1.5e-06 28.0 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR64839.1 - 0.0047 16.8 0.0 0.007 16.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Radical_SAM_N PF08497.5 EMR64839.1 - 0.014 14.3 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal adh_short PF00106.20 EMR64840.1 - 5.4e-22 78.4 0.0 7.4e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR64840.1 - 7.9e-11 42.1 0.0 1.1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR64840.1 - 9.1e-07 28.7 0.0 1.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR64840.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Transp_cyt_pur PF02133.10 EMR64841.1 - 5.7e-39 133.8 23.6 5.7e-39 133.8 16.4 1.8 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin SNF5 PF04855.7 EMR64842.1 - 8.6e-82 274.2 0.0 1.2e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 PIG-X PF08320.7 EMR64842.1 - 0.17 11.1 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 PIG-X / PBN1 GATA PF00320.22 EMR64842.1 - 3.6 7.0 8.8 0.49 9.7 2.9 2.1 2 1 0 2 2 2 0 GATA zinc finger Amidase PF01425.16 EMR64843.1 - 2e-79 267.5 4.4 2.8e-65 220.9 3.0 2.0 1 1 1 2 2 2 2 Amidase Methyltransf_11 PF08241.7 EMR64844.1 - 4.1e-17 62.4 0.0 1.1e-16 61.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR64844.1 - 1.9e-13 50.9 0.0 4.9e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR64844.1 - 1.9e-08 34.2 0.0 4.9e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR64844.1 - 2.8e-08 34.1 0.0 7.3e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR64844.1 - 4.5e-07 30.1 0.0 1.4e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR64844.1 - 1.3e-06 28.1 0.0 3.1e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR64844.1 - 1.3e-06 28.4 1.0 9.7e-06 25.6 0.1 2.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR64844.1 - 0.00017 20.7 0.0 0.0004 19.5 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EMR64844.1 - 0.0052 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 EMR64844.1 - 0.0072 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 EMR64844.1 - 0.074 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 EMR64844.1 - 0.081 13.7 0.0 0.41 11.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Fungal_trans PF04082.13 EMR64845.1 - 8.2e-29 100.2 0.2 1.2e-28 99.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Erg28 PF03694.8 EMR64846.1 - 2.1e-41 140.3 2.2 2.7e-41 140.0 1.5 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF1625 PF07787.7 EMR64846.1 - 0.21 10.8 1.8 0.23 10.6 1.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1625) SWIRM PF04433.12 EMR64847.1 - 1.5e-12 47.4 0.0 4.9e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain MRP-S31 PF15433.1 EMR64847.1 - 0.023 14.1 4.1 0.043 13.2 2.9 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 SHOCT PF09851.4 EMR64847.1 - 5.9 6.5 9.1 0.072 12.5 0.7 2.1 2 0 0 2 2 2 0 Short C-terminal domain Rhodanese PF00581.15 EMR64848.1 - 4.5e-10 39.8 0.1 3.1e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 Rhodanese-like domain Ribonuc_L-PSP PF01042.16 EMR64849.1 - 7.9e-16 57.9 0.0 9.6e-16 57.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP GalP_UDP_tr_C PF02744.12 EMR64850.1 - 7.7e-55 184.9 0.0 1.2e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.17 EMR64850.1 - 1.9e-31 109.5 0.0 1.5e-29 103.4 0.0 2.2 2 0 0 2 2 2 2 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.18 EMR64850.1 - 0.00031 21.1 0.0 0.0032 17.9 0.0 2.2 2 0 0 2 2 2 1 HIT domain O-FucT PF10250.4 EMR64852.1 - 2.2e-14 53.3 0.1 5e-06 25.8 0.0 2.8 3 1 0 3 3 3 2 GDP-fucose protein O-fucosyltransferase Polysacc_deac_1 PF01522.16 EMR64853.1 - 9.3e-11 41.4 0.0 1.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase FMN_dh PF01070.13 EMR64854.1 - 5.3e-76 255.7 3.4 2.3e-51 174.7 0.9 3.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase DHO_dh PF01180.16 EMR64854.1 - 0.00014 20.9 0.1 0.49 9.2 0.0 2.6 2 1 1 3 3 3 2 Dihydroorotate dehydrogenase IMPDH PF00478.20 EMR64854.1 - 0.00058 18.8 0.4 0.003 16.5 0.1 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EMR64854.1 - 0.00073 18.5 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EMR64854.1 - 0.015 14.5 0.1 0.98 8.6 0.0 2.5 1 1 0 2 2 2 0 Histidine biosynthesis protein PhyH PF05721.8 EMR64855.1 - 1.9e-12 47.6 0.0 3e-12 47.0 0.0 1.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SBP_bac_6 PF13343.1 EMR64856.1 - 9.3e-16 57.8 0.1 1.8e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein ADH_zinc_N_2 PF13602.1 EMR64856.1 - 1.4e-15 58.3 0.0 1.2e-14 55.2 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMR64856.1 - 3e-11 42.9 0.2 7.1e-11 41.7 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR64856.1 - 3.1e-09 36.5 0.0 4.1e-07 29.7 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain SBP_bac_11 PF13531.1 EMR64856.1 - 9.6e-09 35.2 0.1 4e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 EMR64856.1 - 0.025 14.3 1.2 0.15 11.7 0.8 2.2 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein adh_short_C2 PF13561.1 EMR64856.1 - 0.08 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DHH PF01368.15 EMR64857.1 - 3.7e-06 26.6 0.0 5.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 DHH family Nucleoporin_C PF03177.9 EMR64858.1 - 7.8e-120 401.1 7.2 1.1e-119 400.6 5.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EMR64858.1 - 9.3e-62 209.1 0.0 1.4e-61 208.5 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Ribosomal_S19e PF01090.14 EMR64859.1 - 0.9 8.9 2.9 3.4 7.1 0.1 2.2 1 1 0 2 2 2 0 Ribosomal protein S19e DUF3516 PF12029.3 EMR64859.1 - 4.3 6.0 7.3 9.5 4.9 0.1 3.0 1 1 3 4 4 4 0 Domain of unknown function (DUF3516) DUF1972 PF09314.6 EMR64859.1 - 4.3 6.7 9.0 53 3.2 0.1 3.8 1 1 1 3 3 3 0 Domain of unknown function (DUF1972) DUF3328 PF11807.3 EMR64860.1 - 5.7e-49 166.7 0.2 7.9e-49 166.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_61 PF03443.9 EMR64861.1 - 7.7e-46 156.6 0.1 8.7e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 p450 PF00067.17 EMR64862.1 - 1.8e-46 158.6 0.0 2.3e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CcmH PF03918.9 EMR64862.1 - 0.15 11.0 0.3 0.29 10.1 0.2 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Cupin_8 PF13621.1 EMR64864.1 - 7.9e-24 84.5 0.0 1.8e-23 83.3 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 EMR64864.1 - 0.00056 19.3 0.0 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.17 EMR64864.1 - 0.00079 19.6 0.0 0.0028 17.8 0.0 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 EMR64864.1 - 0.0017 17.6 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein UPF0220 PF05255.6 EMR64867.1 - 6.8e-62 207.5 4.0 7.6e-62 207.4 2.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Mito_carr PF00153.22 EMR64868.1 - 1.6e-38 130.2 0.4 1.3e-19 69.6 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein SMI1_KNR4 PF09346.5 EMR64869.1 - 6.2e-23 81.2 0.0 1.4e-22 80.0 0.0 1.6 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Aldolase_II PF00596.16 EMR64871.1 - 2.3e-48 164.2 0.1 2.8e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TES PF08034.6 EMR64871.1 - 0.11 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Trematode eggshell synthesis protein Urm1 PF09138.6 EMR64872.1 - 1.8e-34 117.7 0.0 2.1e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EMR64872.1 - 0.0012 19.1 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 ThiS family dCMP_cyt_deam_1 PF00383.17 EMR64873.1 - 9.5e-17 60.5 0.2 1.3e-16 60.0 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EMR64873.1 - 2.5e-08 33.9 0.1 3.4e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EMR64873.1 - 0.00018 20.9 0.5 0.055 12.8 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Sugar_tr PF00083.19 EMR64875.1 - 5.2e-94 315.3 28.7 6.4e-94 315.0 19.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR64875.1 - 1.4e-20 73.3 19.4 1.4e-20 73.3 13.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR64875.1 - 0.36 9.1 30.3 0.037 12.4 10.6 3.4 2 2 2 4 4 4 0 MFS/sugar transport protein DUF3361 PF11841.3 EMR64876.1 - 0.0092 15.7 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) HEAT PF02985.17 EMR64876.1 - 0.02 14.9 0.1 0.089 12.9 0.0 2.2 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.1 EMR64876.1 - 0.061 13.8 0.2 0.29 11.6 0.1 2.0 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.1 EMR64876.1 - 0.094 13.0 0.1 0.24 11.6 0.0 1.7 2 1 0 2 2 2 0 HEAT repeats Abhydrolase_6 PF12697.2 EMR64877.1 - 1.5e-23 83.9 3.0 2.6e-23 83.1 2.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR64877.1 - 4e-12 46.1 0.0 1.8e-11 44.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR64877.1 - 4.8e-10 39.3 0.0 1.2e-09 38.0 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMR64877.1 - 3.1e-06 26.9 0.0 7.2e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EMR64877.1 - 0.00025 20.3 0.0 0.00076 18.8 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.15 EMR64877.1 - 0.024 14.0 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.8 EMR64877.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF2048 PF09752.4 EMR64877.1 - 0.11 11.3 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF676 PF05057.9 EMR64877.1 - 0.14 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EMR64877.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ndr PF03096.9 EMR64877.1 - 0.18 10.2 0.1 3.1 6.1 0.1 2.1 2 0 0 2 2 2 0 Ndr family LRS4 PF10422.4 EMR64877.1 - 0.23 10.7 0.1 0.33 10.2 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 adh_short_C2 PF13561.1 EMR64878.1 - 6.4e-13 49.0 0.0 7.5e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR64878.1 - 2.8e-08 33.8 0.2 4.5e-08 33.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR64878.1 - 0.0099 15.5 0.4 0.017 14.8 0.3 1.3 1 0 0 1 1 1 1 KR domain DUF1772 PF08592.6 EMR64879.1 - 0.01 15.5 1.9 0.01 15.5 1.3 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) PepSY_TM_2 PF13703.1 EMR64879.1 - 1.1 9.5 4.2 0.35 11.0 0.3 2.0 2 0 0 2 2 2 0 PepSY-associated TM helix PfkB PF00294.19 EMR64880.1 - 3.9e-10 39.3 0.0 3e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EMR64880.1 - 0.049 12.8 0.0 0.78 8.8 0.0 2.1 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase adh_short_C2 PF13561.1 EMR64881.1 - 3.3e-21 76.1 0.0 4.6e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR64881.1 - 3.2e-20 72.7 1.0 4.2e-20 72.3 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR64881.1 - 2.6e-08 33.7 1.5 1.1e-07 31.7 1.1 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR64881.1 - 0.076 12.4 0.1 0.24 10.7 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMR64883.1 - 6.7e-25 87.9 2.3 1.6e-24 86.7 1.6 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR64883.1 - 2.6e-12 47.0 0.0 3.9e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR64883.1 - 3.5e-07 30.0 3.8 3.9e-06 26.6 2.6 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR64883.1 - 2.6e-05 23.7 0.4 6.2e-05 22.5 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR64883.1 - 0.00024 21.1 0.1 0.00045 20.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMR64883.1 - 0.0024 16.6 0.2 0.0034 16.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.14 EMR64883.1 - 0.0085 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EMR64883.1 - 0.048 13.3 1.0 0.096 12.3 0.7 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EMR64883.1 - 0.08 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.13 EMR64883.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain zf-GRF PF06839.7 EMR64884.1 - 2.9e-09 36.6 6.9 5.6e-09 35.7 4.8 1.5 1 0 0 1 1 1 1 GRF zinc finger DUF1764 PF08576.5 EMR64884.1 - 0.072 13.8 0.0 0.072 13.8 0.0 3.8 5 0 0 5 5 5 0 Eukaryotic protein of unknown function (DUF1764) FUSC PF04632.7 EMR64884.1 - 0.61 8.4 7.2 0.89 7.9 5.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family ERM PF00769.14 EMR64884.1 - 4.8 6.6 11.1 0.4 10.1 2.4 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Glyco_hydro_63 PF03200.11 EMR64885.1 - 1.5e-08 33.0 7.0 9e-07 27.1 0.1 4.1 4 1 0 4 4 4 2 Mannosyl oligosaccharide glucosidase Aldo_ket_red PF00248.16 EMR64886.1 - 2.4e-64 216.9 0.0 2.7e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FMN_red PF03358.10 EMR64887.1 - 5.3e-14 51.9 0.0 9.2e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EMR64887.1 - 2.8e-06 26.9 0.0 4.7e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold Corona_3 PF04694.7 EMR64887.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Coronavirus ORF3 protein Ribosomal_S27e PF01667.12 EMR64887.1 - 0.13 11.8 0.3 0.25 10.9 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 adh_short_C2 PF13561.1 EMR64888.1 - 2.9e-27 95.9 0.0 3.5e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR64888.1 - 9.2e-27 93.9 0.0 1.2e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR64888.1 - 6.2e-09 35.7 0.0 9.1e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DNA_pol3_beta_3 PF02768.10 EMR64888.1 - 0.052 13.1 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain DUF1921 PF09081.5 EMR64888.1 - 0.27 11.2 1.9 0.32 10.9 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1921) SNF2_N PF00176.18 EMR64889.1 - 2.4e-10 39.7 0.0 8.2e-09 34.6 0.0 2.6 2 1 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 EMR64889.1 - 2.7e-05 24.0 1.4 0.18 11.5 0.1 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMR64889.1 - 4.9e-05 23.1 0.0 0.00017 21.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMR64889.1 - 9.6e-05 21.9 0.0 0.02 14.3 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase FAD_binding_3 PF01494.14 EMR64890.1 - 8.1e-27 94.1 0.0 1.2e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR64890.1 - 1e-11 44.3 4.0 1.1e-05 24.5 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR64890.1 - 2.3e-07 31.0 0.3 0.0012 19.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR64890.1 - 7.4e-07 29.2 0.0 2.4e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR64890.1 - 6.5e-06 24.8 2.4 0.00092 17.7 0.8 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EMR64890.1 - 1.5e-05 24.0 4.1 2.3e-05 23.4 2.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EMR64890.1 - 9.2e-05 22.5 0.0 0.00022 21.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR64890.1 - 0.00034 19.6 0.2 0.0029 16.5 0.4 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EMR64890.1 - 0.00041 19.5 2.5 0.00078 18.6 1.7 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR64890.1 - 0.00051 20.0 1.0 0.0013 18.7 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EMR64890.1 - 0.0015 17.4 0.0 0.0071 15.2 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Thi4 PF01946.12 EMR64890.1 - 0.0029 16.7 0.4 0.0046 16.0 0.3 1.2 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 EMR64890.1 - 0.044 12.8 0.0 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EMR64890.1 - 0.11 11.1 0.9 0.18 10.4 0.3 1.5 1 1 1 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.16 EMR64890.1 - 0.12 11.9 0.2 0.23 11.0 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EMR64890.1 - 0.19 10.6 1.5 1.2 7.9 1.0 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.11 EMR64891.1 - 6.6e-17 61.2 12.6 8e-17 60.9 8.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3505 PF12013.3 EMR64892.1 - 0.044 14.0 0.1 0.092 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) adh_short PF00106.20 EMR64893.1 - 4.8e-26 91.6 0.4 7.5e-26 91.0 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR64893.1 - 1.7e-24 86.9 0.0 2.1e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR64893.1 - 0.0001 22.0 0.1 0.00013 21.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMR64893.1 - 0.006 16.3 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 EMR64893.1 - 0.028 14.0 0.6 0.13 11.8 0.4 1.9 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.16 EMR64893.1 - 0.042 13.2 0.1 0.066 12.6 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family LytR_C PF13399.1 EMR64893.1 - 0.046 14.1 0.2 2.4 8.6 0.5 2.5 2 2 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator THF_DHG_CYH_C PF02882.14 EMR64893.1 - 0.067 12.2 0.3 1.6 7.7 0.0 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Bromodomain PF00439.20 EMR64894.1 - 5.8e-28 96.6 0.8 1.1e-27 95.7 0.5 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EMR64894.1 - 1.8e-09 37.6 0.1 4.3e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR64894.1 - 5e-09 36.0 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_hydro_43 PF04616.9 EMR64895.1 - 2e-22 79.6 0.0 2.3e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Rad1 PF02144.11 EMR64897.1 - 1.9e-51 174.4 0.0 2.2e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 GFA PF04828.9 EMR64898.1 - 3.6e-19 68.4 6.8 1.1e-10 41.3 0.2 3.4 2 1 1 3 3 3 3 Glutathione-dependent formaldehyde-activating enzyme KH_1 PF00013.24 EMR64899.1 - 0.083 12.5 0.1 0.34 10.5 0.1 2.0 1 1 0 1 1 1 0 KH domain F-box-like PF12937.2 EMR64900.1 - 9.1e-05 22.1 1.2 0.0017 18.0 0.8 2.4 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EMR64900.1 - 0.018 14.7 0.1 6.5 6.5 0.1 2.4 2 0 0 2 2 2 0 F-box domain FAA_hydrolase PF01557.13 EMR64901.1 - 1.2e-49 168.7 0.0 1.7e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EMR64901.1 - 2.6e-23 82.0 0.0 5e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal PBP1_TM PF14812.1 EMR64902.1 - 0.16 12.2 9.1 0.22 11.8 6.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2201_N PF13203.1 EMR64902.1 - 2.4 7.2 8.5 3.5 6.7 5.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Gly-zipper_OmpA PF13436.1 EMR64902.1 - 2.6 7.7 13.1 3.8 7.1 8.8 1.5 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain NTP_transferase PF00483.18 EMR64903.1 - 1.1e-26 93.7 0.0 1.3e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EMR64903.1 - 5.2e-09 35.2 5.8 1.3e-05 24.4 0.0 4.0 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EMR64903.1 - 8.8e-06 25.8 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EMR64903.1 - 0.062 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF2968 PF11180.3 EMR64903.1 - 0.092 12.1 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Peptidase_M54 PF07998.6 EMR64905.1 - 5.4e-08 32.8 0.2 1.3e-07 31.5 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M54 Glyco_hydro_43 PF04616.9 EMR64906.1 - 3.9e-33 114.7 1.4 1.1e-31 110.0 1.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Aldedh PF00171.17 EMR64907.1 - 6.5e-76 255.5 2.7 4.6e-41 140.6 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family DUF605 PF04652.11 EMR64908.1 - 4.2 6.6 12.1 5.4 6.3 8.4 1.1 1 0 0 1 1 1 0 Vta1 like WEMBL PF05701.6 EMR64909.1 - 0.00096 17.7 20.1 0.0016 17.0 13.9 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light TSC22 PF01166.13 EMR64909.1 - 0.65 10.0 7.1 0.66 9.9 0.2 3.7 2 2 3 5 5 5 0 TSC-22/dip/bun family Reo_sigmaC PF04582.7 EMR64909.1 - 0.83 8.7 11.8 0.16 11.1 2.7 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Mto2_bdg PF12808.2 EMR64909.1 - 0.84 9.7 12.7 0.63 10.1 0.2 3.5 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PLRV_ORF5 PF01690.12 EMR64909.1 - 1.1 8.2 12.6 1.5 7.9 8.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein AbiH PF14253.1 EMR64909.1 - 1.2 8.7 11.5 8.2 5.9 5.9 2.4 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH ATG16 PF08614.6 EMR64909.1 - 3.3 7.4 25.8 1.1 9.0 10.2 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CALCOCO1 PF07888.6 EMR64909.1 - 5 5.2 21.2 9.5 4.3 14.7 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.6 EMR64909.1 - 5.2 5.6 24.4 0.26 9.9 6.0 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF641 PF04859.7 EMR64909.1 - 5.5 6.7 16.8 1.3 8.7 2.6 4.0 1 1 4 5 5 5 0 Plant protein of unknown function (DUF641) GrpE PF01025.14 EMR64909.1 - 6.5 6.2 18.3 45 3.5 12.7 2.2 1 1 0 1 1 1 0 GrpE USP8_interact PF08941.5 EMR64909.1 - 7.3 5.8 9.4 0.19 11.0 0.7 2.6 2 1 1 4 4 4 0 USP8 interacting Epimerase PF01370.16 EMR64910.1 - 3.9e-08 33.0 0.1 0.0035 16.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR64910.1 - 5.3e-06 25.5 0.1 1.3e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EMR64910.1 - 0.00011 21.5 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EMR64910.1 - 0.00097 19.4 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EMR64910.1 - 0.0011 19.0 0.4 0.0032 17.4 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding DXP_reductoisom PF02670.11 EMR64910.1 - 0.025 15.1 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF1996 PF09362.5 EMR64911.1 - 5.7e-88 294.5 1.0 6.9e-88 294.2 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF605 PF04652.11 EMR64912.1 - 0.42 9.9 40.0 0.47 9.7 27.8 1.0 1 0 0 1 1 1 0 Vta1 like PLRV_ORF5 PF01690.12 EMR64912.1 - 1.8 7.6 28.4 2.1 7.4 19.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SOBP PF15279.1 EMR64912.1 - 4.1 7.6 24.8 5.3 7.3 17.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein TFIIA PF03153.8 EMR64912.1 - 6.5 6.5 42.6 7.3 6.3 29.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fungal_trans PF04082.13 EMR64914.1 - 4.5e-11 42.1 0.8 2.1e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain TetR_N PF00440.18 EMR64914.1 - 0.33 10.6 1.8 0.4 10.3 0.0 2.0 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family DHDPS PF00701.17 EMR64915.1 - 2.1e-67 226.7 0.0 2.4e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Proteasome PF00227.21 EMR64916.1 - 2.2e-60 203.1 0.1 2.7e-60 202.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMR64916.1 - 2.8e-14 52.0 0.4 6.9e-14 50.8 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EMR64916.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit TFIIS_M PF07500.9 EMR64917.1 - 3.1e-15 56.2 2.3 7.7e-15 54.9 1.6 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EMR64917.1 - 2.8e-13 50.3 0.0 8.2e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 SPOC domain PHD PF00628.24 EMR64917.1 - 5.3e-09 35.6 7.3 9.5e-09 34.8 5.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EMR64917.1 - 0.16 11.3 2.9 0.29 10.4 2.0 1.4 1 0 0 1 1 1 0 PHD-finger PHD_3 PF13922.1 EMR64917.1 - 1.3 9.3 4.4 7.1 6.9 3.1 2.4 1 1 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx BSP_II PF05432.6 EMR64918.1 - 0.0044 16.3 16.4 0.007 15.6 11.4 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) BUD22 PF09073.5 EMR64918.1 - 0.016 14.3 3.5 0.02 13.9 2.5 1.2 1 0 0 1 1 1 0 BUD22 Adeno_E3_CR2 PF02439.10 EMR64918.1 - 0.027 14.0 0.1 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 EMR64918.1 - 0.044 14.1 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CDC45 PF02724.9 EMR64918.1 - 0.05 11.6 0.8 0.064 11.2 0.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BatD PF13584.1 EMR64918.1 - 0.052 12.1 0.0 0.077 11.5 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance eIF-3c_N PF05470.7 EMR64918.1 - 0.062 11.3 0.4 0.073 11.1 0.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Shisa PF13908.1 EMR64918.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 EMR64918.1 - 0.16 10.2 0.7 0.86 7.8 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 EMR64918.1 - 0.46 9.8 4.0 0.84 8.9 2.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2457 PF10446.4 EMR64918.1 - 0.86 8.2 9.3 1.5 7.4 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CcmD PF04995.9 EMR64918.1 - 1.4 8.7 5.8 0.46 10.2 0.4 2.2 1 1 1 2 2 2 0 Heme exporter protein D (CcmD) Daxx PF03344.10 EMR64918.1 - 1.9 6.8 13.5 0.16 10.4 5.1 1.9 2 0 0 2 2 2 0 Daxx Family Mpp10 PF04006.7 EMR64918.1 - 7.1 4.8 14.0 12 4.1 9.7 1.2 1 0 0 1 1 1 0 Mpp10 protein DUF1109 PF06532.6 EMR64919.1 - 0.038 13.4 0.2 0.07 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1109) DGF-1_C PF11040.3 EMR64919.1 - 0.043 13.6 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus p450 PF00067.17 EMR64920.1 - 1.3e-73 248.1 0.0 1.6e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Formyl_trans_N PF00551.14 EMR64921.1 - 4.4e-38 130.6 0.2 5.6e-38 130.2 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 EMR64921.1 - 2.2e-11 43.0 0.0 1.3e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 EMR64921.1 - 0.00013 21.5 0.0 0.00051 19.6 0.0 2.0 2 0 0 2 2 2 1 ACT domain RWD PF05773.17 EMR64923.1 - 1.9e-24 85.7 0.5 2.6e-24 85.2 0.3 1.2 1 0 0 1 1 1 1 RWD domain GreA_GreB_N PF03449.10 EMR64923.1 - 0.057 13.4 0.4 0.057 13.4 0.3 2.1 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal SUV3_C PF12513.3 EMR64923.1 - 0.11 11.9 0.3 0.67 9.4 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal CPL PF08144.6 EMR64925.1 - 9e-16 58.0 2.6 3.4e-15 56.1 0.0 3.1 4 0 0 4 4 4 1 CPL (NUC119) domain Rhomboid PF01694.17 EMR64926.1 - 1.8e-18 66.9 14.1 1.8e-18 66.9 9.7 1.4 2 0 0 2 2 2 1 Rhomboid family TPR_12 PF13424.1 EMR64927.1 - 2.2e-11 43.4 12.8 4.7e-06 26.4 4.5 3.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMR64927.1 - 2.3e-09 37.6 36.6 0.00031 21.3 11.3 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMR64927.1 - 7.3e-09 34.8 20.9 8.6e-06 25.2 0.5 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMR64927.1 - 2.4e-08 33.8 29.7 0.0047 17.4 1.2 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMR64927.1 - 1.1e-07 31.0 11.1 9.2e-05 21.9 0.2 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMR64927.1 - 2.5e-06 26.8 0.4 0.00093 18.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR64927.1 - 3.7e-06 27.1 30.0 0.073 13.4 1.2 4.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMR64927.1 - 1.2e-05 24.8 17.2 0.0048 16.5 0.2 4.1 4 2 3 7 7 7 4 TPR repeat TPR_1 PF00515.23 EMR64927.1 - 0.00016 21.1 0.3 0.00016 21.1 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMR64927.1 - 0.00058 19.8 1.3 11 6.5 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMR64927.1 - 0.00071 19.8 10.5 3.5 8.2 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 EMR64927.1 - 0.065 13.6 0.6 0.065 13.6 0.4 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Asp PF00026.18 EMR64928.1 - 1.6e-67 228.0 5.8 2e-67 227.6 4.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EMR64928.1 - 1.2e-06 28.8 1.6 0.01 16.2 0.4 3.8 2 2 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EMR64928.1 - 2.4e-06 27.6 0.2 2.4e-06 27.6 0.2 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EMR64928.1 - 2e-05 24.1 0.0 4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal ATP-synt_C PF00137.16 EMR64929.1 - 5.1e-12 45.5 24.1 1.8e-09 37.3 6.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Preseq_ALAS PF09029.5 EMR64929.1 - 0.14 12.2 0.1 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence MFS_1 PF07690.11 EMR64930.1 - 1.1e-17 63.8 30.9 1.8e-17 63.0 21.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR64930.1 - 1.4e-15 56.5 10.0 1.9e-15 56.1 7.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMR64930.1 - 2.4e-05 23.0 11.6 2.4e-05 23.0 8.1 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3021 PF11457.3 EMR64930.1 - 0.89 9.4 6.0 1.7 8.5 0.2 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF3021) Acyl_transf_3 PF01757.17 EMR64931.1 - 8.5e-26 90.5 13.9 8.6e-19 67.5 5.3 2.3 2 0 0 2 2 2 2 Acyltransferase family Lactamase_B_2 PF12706.2 EMR64933.1 - 2.1e-24 86.1 0.0 2.6e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMR64933.1 - 4.3e-13 49.3 0.0 6.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMR64933.1 - 0.035 13.7 2.3 0.064 12.9 1.6 1.5 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily E1-E2_ATPase PF00122.15 EMR64934.1 - 1.2e-61 207.7 7.2 2.1e-61 206.8 5.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMR64934.1 - 4.1e-30 105.8 0.1 1.3e-24 87.8 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EMR64934.1 - 5.5e-30 104.2 2.5 5.5e-30 104.2 1.7 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EMR64934.1 - 4.6e-15 55.3 0.0 8.7e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMR64934.1 - 1.2e-13 51.7 3.9 2.7e-13 50.4 2.7 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMR64934.1 - 2e-05 24.2 1.8 0.0002 21.0 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Peptidase_S8 PF00082.17 EMR64935.1 - 9.2e-51 172.6 10.9 1.3e-50 172.1 7.5 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMR64935.1 - 6.9e-14 52.1 1.5 1.3e-13 51.2 1.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Amidohydro_3 PF07969.6 EMR64936.1 - 1e-56 192.9 4.5 1.3e-56 192.5 3.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMR64936.1 - 7.6e-09 35.2 0.1 2.4e-08 33.6 0.1 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EMR64936.1 - 4.5e-07 29.8 0.1 0.034 13.7 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family Vps16_C PF04840.7 EMR64936.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Vps16, C-terminal region Amidohydro_4 PF13147.1 EMR64936.1 - 0.18 11.8 0.1 0.18 11.8 0.1 3.6 3 1 0 3 3 3 0 Amidohydrolase Sugar_tr PF00083.19 EMR64937.1 - 1e-79 268.2 36.0 6.8e-66 222.6 18.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR64937.1 - 2.3e-25 89.0 26.7 7.4e-25 87.3 15.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR64937.1 - 0.00012 20.4 3.5 0.00025 19.3 2.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CKAP2_C PF15297.1 EMR64938.1 - 0.81 8.4 6.3 4.2 6.0 4.2 2.0 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus Cu-oxidase_3 PF07732.10 EMR64939.1 - 5.3e-42 142.2 1.2 5.3e-42 142.2 0.9 3.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMR64939.1 - 4.6e-41 139.5 6.4 5.7e-38 129.5 0.7 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EMR64939.1 - 1.6e-33 115.8 0.1 2e-32 112.2 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Zn_clus PF00172.13 EMR64940.1 - 0.00021 21.1 11.8 0.00037 20.3 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2461 PF09365.5 EMR64940.1 - 0.064 12.6 0.1 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) Mtc PF03820.12 EMR64941.1 - 1.5e-102 342.3 0.3 9.7e-102 339.7 0.2 1.8 1 1 0 1 1 1 1 Tricarboxylate carrier VIT1 PF01988.14 EMR64942.1 - 0.0096 15.4 2.2 0.0096 15.4 1.5 1.1 1 0 0 1 1 1 1 VIT family DUF4018 PF13210.1 EMR64942.1 - 0.014 14.8 0.4 0.016 14.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) MAPEG PF01124.13 EMR64942.1 - 0.059 12.9 5.2 0.074 12.6 3.6 1.2 1 0 0 1 1 1 0 MAPEG family DUF4131 PF13567.1 EMR64942.1 - 1.4 8.3 5.0 1.5 8.1 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pkinase PF00069.20 EMR64943.1 - 6e-34 117.3 0.0 7.5e-28 97.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR64943.1 - 1.6e-13 50.3 0.0 2.4e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1357 PF07094.6 EMR64943.1 - 4.8e-07 29.4 0.7 0.0014 18.1 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1357) Pox_ser-thr_kin PF05445.6 EMR64943.1 - 0.036 12.8 0.1 0.053 12.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EMR64943.1 - 0.078 12.3 0.1 0.34 10.2 0.0 2.1 2 1 0 2 2 2 0 RIO1 family Exo_endo_phos PF03372.18 EMR64945.1 - 1.3e-15 58.0 0.7 1.8e-15 57.5 0.5 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family He_PIG PF05345.7 EMR64945.1 - 0.014 15.3 6.0 0.057 13.4 4.2 2.1 1 0 0 1 1 1 0 Putative Ig domain Exo_endo_phos_2 PF14529.1 EMR64945.1 - 0.079 12.5 0.0 0.79 9.3 0.0 2.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Aldo_ket_red PF00248.16 EMR64946.1 - 1.2e-72 244.1 0.0 1.4e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fe-ADH PF00465.14 EMR64947.1 - 9.2e-50 169.2 1.1 8.6e-34 116.7 0.2 2.0 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EMR64947.1 - 3.5e-10 39.6 0.0 5.3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF1237 PF06824.6 EMR64948.1 - 6.4e-154 512.6 0.0 7.3e-154 512.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) RNase_H PF00075.19 EMR64949.1 - 0.00061 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 RNase H DUF3812 PF12757.2 EMR64949.1 - 0.95 9.4 5.1 1.3 8.9 0.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3812) CAP18_C PF12153.3 EMR64949.1 - 6 6.5 7.2 1.1 8.9 0.4 2.4 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) LigB PF02900.13 EMR64950.1 - 5.5e-46 156.7 0.0 6.3e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MFS_1 PF07690.11 EMR64951.1 - 1.3e-25 89.9 20.5 1.3e-25 89.9 14.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR64951.1 - 4.1e-07 28.5 6.3 6.5e-07 27.9 4.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HgmA PF04209.8 EMR64953.1 - 8.1e-131 436.2 0.3 2.8e-105 352.1 0.0 2.0 1 1 1 2 2 2 2 homogentisate 1,2-dioxygenase Fungal_trans_2 PF11951.3 EMR64954.1 - 6e-46 156.7 0.2 9.7e-46 156.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2434 PF10361.4 EMR64955.1 - 1.6e-107 359.0 4.5 2e-107 358.7 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) MFS_1 PF07690.11 EMR64955.1 - 2.7 6.6 14.3 0.7 8.5 4.6 2.2 1 1 1 2 2 2 0 Major Facilitator Superfamily COesterase PF00135.23 EMR64957.1 - 4.2e-24 85.1 0.0 3.2e-17 62.4 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family adh_short PF00106.20 EMR64958.1 - 7.5e-05 22.6 0.7 0.0002 21.3 0.5 1.7 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EMR64958.1 - 0.00061 18.7 0.1 0.00078 18.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EMR64958.1 - 0.0022 18.0 0.1 0.0032 17.4 0.1 1.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR64958.1 - 0.005 16.2 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF883 PF05957.8 EMR64959.1 - 0.029 14.7 6.2 0.038 14.4 4.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Occludin_ELL PF07303.8 EMR64959.1 - 0.036 14.8 1.9 0.05 14.3 1.3 1.3 1 0 0 1 1 1 0 Occludin homology domain Macoilin PF09726.4 EMR64959.1 - 0.037 12.3 5.8 0.036 12.3 4.0 1.0 1 0 0 1 1 1 0 Transmembrane protein GP41 PF00517.12 EMR64959.1 - 0.038 13.5 0.9 0.045 13.3 0.6 1.1 1 0 0 1 1 1 0 Retroviral envelope protein SATase_N PF06426.9 EMR64959.1 - 0.072 13.3 1.6 0.093 12.9 1.0 1.4 1 1 0 1 1 1 0 Serine acetyltransferase, N-terminal DUF3584 PF12128.3 EMR64959.1 - 0.12 9.6 7.8 0.12 9.7 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4446 PF14584.1 EMR64959.1 - 0.13 12.0 1.2 0.19 11.5 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2514 PF10721.4 EMR64959.1 - 0.15 11.7 14.6 0.17 11.6 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) ATP-synt_B PF00430.13 EMR64959.1 - 0.18 11.6 11.5 0.26 11.0 8.0 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DivIVA PF05103.8 EMR64959.1 - 0.25 11.3 9.9 0.32 11.0 6.9 1.2 1 0 0 1 1 1 0 DivIVA protein Phage_lysis PF03245.8 EMR64959.1 - 0.29 11.1 9.7 0.33 10.9 6.7 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein DUF2229 PF09989.4 EMR64959.1 - 0.37 10.2 2.4 0.37 10.2 1.6 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Fmp27_WPPW PF10359.4 EMR64959.1 - 0.38 9.1 4.2 0.39 9.0 2.9 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Mnd1 PF03962.10 EMR64959.1 - 0.61 9.7 5.9 0.66 9.6 4.1 1.1 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 EMR64959.1 - 0.63 9.6 5.8 0.66 9.5 4.1 1.1 1 0 0 1 1 1 0 IncA protein DUF4407 PF14362.1 EMR64959.1 - 0.65 8.8 5.6 0.64 8.9 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_Mu_Gam PF07352.7 EMR64959.1 - 0.9 9.0 7.6 1.2 8.6 5.3 1.1 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DivIC PF04977.10 EMR64959.1 - 1.3 8.5 9.8 0.24 10.8 3.2 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF4337 PF14235.1 EMR64959.1 - 1.7 8.4 8.1 2 8.2 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3391 PF11871.3 EMR64959.1 - 2.1 8.5 5.7 2.8 8.1 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) GrpE PF01025.14 EMR64959.1 - 3 7.3 9.6 2.9 7.4 6.0 1.4 1 1 1 2 2 2 0 GrpE Atg14 PF10186.4 EMR64959.1 - 3.2 6.5 6.3 3.7 6.4 4.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DASH_Spc19 PF08287.6 EMR64959.1 - 3.5 7.2 8.7 0.45 10.1 0.2 2.0 1 1 1 2 2 2 0 Spc19 DUF1423 PF07227.6 EMR64959.1 - 4.3 5.8 7.3 4.6 5.7 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) APG6 PF04111.7 EMR64959.1 - 4.9 6.0 9.1 4.9 6.0 6.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 ATP-synt_E PF05680.7 EMR64959.1 - 5.5 7.0 8.0 6.4 6.8 5.6 1.2 1 0 0 1 1 1 0 ATP synthase E chain Bap31 PF05529.7 EMR64959.1 - 6.3 6.2 7.2 7.2 6.0 5.0 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like NmrA PF05368.8 EMR64960.1 - 1.1e-61 208.0 0.2 1.7e-61 207.4 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Aldedh PF00171.17 EMR64960.1 - 7.2e-52 176.2 1.4 4.2e-36 124.2 0.1 2.6 2 1 1 3 3 3 2 Aldehyde dehydrogenase family NAD_binding_10 PF13460.1 EMR64960.1 - 3.8e-10 40.0 0.1 1.2e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMR64960.1 - 0.037 12.7 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aminotran_3 PF00202.16 EMR64961.1 - 2.2e-78 263.4 0.0 2.8e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EMR64961.1 - 3.4e-05 22.9 0.0 0.0002 20.4 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Aa_trans PF01490.13 EMR64962.1 - 3.1e-60 203.7 38.5 3.6e-60 203.5 26.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein 2OG-FeII_Oxy PF03171.15 EMR64963.1 - 1.2e-12 48.0 0.0 3.3e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMR64963.1 - 9.5e-11 42.2 0.0 2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal NAP PF00956.13 EMR64964.1 - 2e-27 95.8 0.2 2.7e-27 95.4 0.2 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) EF-hand_1 PF00036.27 EMR64965.1 - 1.1e-21 74.4 1.9 2.9e-09 35.5 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EMR64965.1 - 6.8e-20 70.4 1.0 6.6e-14 51.2 0.1 3.3 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 EMR64965.1 - 1.4e-18 66.7 0.1 1.1e-12 47.9 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EMR64965.1 - 1.5e-13 49.3 0.0 0.00016 21.2 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 EMR64965.1 - 8.9e-10 37.4 7.1 4.7e-05 22.5 0.2 3.2 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 EMR64965.1 - 3.8e-08 33.1 0.0 8.5e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.2 EMR64965.1 - 2.4e-05 24.0 0.1 0.00028 20.5 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Tricorn_C1 PF14684.1 EMR64965.1 - 0.012 15.4 0.1 0.08 12.8 0.0 2.4 3 1 1 4 4 3 0 Tricorn protease C1 domain SPARC_Ca_bdg PF10591.4 EMR64965.1 - 0.013 15.5 0.1 0.46 10.5 0.0 2.5 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EMR64965.1 - 0.039 13.5 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) AAA_35 PF14516.1 EMR64965.1 - 0.058 12.0 0.0 2.1 6.8 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain Adenine_glyco PF03352.8 EMR64965.1 - 0.066 12.7 0.1 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 Methyladenine glycosylase DnaB_2 PF07261.6 EMR64965.1 - 0.12 11.9 0.3 5.9 6.5 0.0 2.8 3 0 0 3 3 3 0 Replication initiation and membrane attachment DNase_II PF03265.10 EMR64965.1 - 0.13 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Deoxyribonuclease II UPF0506 PF11703.3 EMR64966.1 - 0.028 14.3 0.2 0.042 13.8 0.1 1.3 1 0 0 1 1 1 0 UPF0506 Amidohydro_1 PF01979.15 EMR64967.1 - 1e-21 77.9 1.0 2.7e-11 43.7 0.5 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EMR64967.1 - 5.5e-12 46.2 15.0 3.6e-11 43.6 10.4 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EMR64967.1 - 5.3e-11 42.1 1.1 9.6e-10 38.1 0.1 2.8 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 EMR64967.1 - 0.0071 15.6 13.9 0.032 13.4 0.9 2.8 2 2 1 3 3 3 2 Amidohydrolase family Rep_fac-A_C PF08646.5 EMR64968.1 - 2.1e-57 192.9 3.6 1.4e-54 183.7 0.5 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EMR64968.1 - 4.3e-19 68.1 0.0 9.2e-19 67.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EMR64968.1 - 1.6e-17 63.1 1.2 2.7e-11 43.1 0.0 5.0 4 1 1 5 5 5 3 OB-fold nucleic acid binding domain DUF223 PF02721.9 EMR64968.1 - 0.0018 18.3 0.2 0.0039 17.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF223 zf-like PF04071.7 EMR64968.1 - 0.045 13.4 0.2 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain DUF753 PF05444.7 EMR64968.1 - 0.068 13.0 1.0 0.94 9.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF753) MFS_1 PF07690.11 EMR64969.1 - 3.2e-14 52.4 46.0 3.2e-14 52.4 31.9 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMR64969.1 - 1.8e-06 27.5 4.1 1.8e-06 27.5 2.9 2.8 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 AMP-binding PF00501.23 EMR64970.1 - 0.011 14.1 0.0 0.018 13.4 0.0 1.3 1 0 0 1 1 1 0 AMP-binding enzyme SR-25 PF10500.4 EMR64970.1 - 0.041 13.3 13.7 0.05 13.0 9.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 EMR64970.1 - 0.72 9.9 14.8 1.3 9.0 10.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AF-4 PF05110.8 EMR64970.1 - 2.3 5.9 15.0 2.6 5.7 10.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ADH_zinc_N PF00107.21 EMR64971.1 - 9.3e-23 80.2 0.1 2e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR64971.1 - 3e-17 63.6 0.2 1.1e-16 61.8 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR64971.1 - 8.6e-10 38.3 0.0 4.1e-09 36.1 0.0 2.0 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Bac_rhodopsin PF01036.13 EMR64972.1 - 5.1e-48 163.3 19.2 7e-48 162.8 13.3 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Ctr PF04145.10 EMR64973.1 - 0.065 13.2 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family CENP-T PF15511.1 EMR64973.1 - 0.26 10.4 8.8 0.34 10.0 6.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T 2Fe-2S_thioredx PF01257.14 EMR64974.1 - 2e-60 202.6 0.1 2.5e-60 202.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Kelch_3 PF13415.1 EMR64975.1 - 7.1e-34 115.2 15.3 2.4e-09 37.0 0.1 9.1 8 1 0 8 8 8 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EMR64975.1 - 2.2e-24 84.9 13.6 1.4e-08 34.3 0.0 7.0 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EMR64975.1 - 9.7e-24 82.8 0.1 9.8e-05 22.2 0.0 6.9 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.1 EMR64975.1 - 2.7e-17 62.0 3.3 0.00056 19.9 0.1 5.8 4 2 2 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EMR64975.1 - 3.6e-15 55.2 6.4 4.3e-05 22.9 0.0 5.5 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EMR64975.1 - 1.8e-13 49.6 1.3 0.00019 21.0 0.0 5.4 5 0 0 5 5 5 3 Kelch motif dCMP_cyt_deam_1 PF00383.17 EMR64976.1 - 5.3e-07 29.2 0.0 0.00013 21.5 0.0 2.9 3 0 0 3 3 3 2 Cytidine and deoxycytidylate deaminase zinc-binding region BAF1_ABF1 PF04684.8 EMR64976.1 - 2 7.1 15.2 3 6.5 10.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SerH PF06873.6 EMR64977.1 - 0.011 14.4 2.3 0.013 14.1 1.6 1.1 1 0 0 1 1 1 0 Cell surface immobilisation antigen SerH DLH PF01738.13 EMR64978.1 - 2.6e-23 82.4 0.0 1.2e-21 76.9 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMR64978.1 - 3e-10 40.0 0.1 4.4e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR64978.1 - 7.1e-05 22.7 0.2 0.032 14.0 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMR64978.1 - 0.0098 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AhpC-TSA PF00578.16 EMR64979.1 - 3.6e-26 91.2 0.0 6e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMR64979.1 - 8.6e-17 61.0 0.0 1.2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EMR64979.1 - 0.00027 20.8 0.0 0.0024 17.7 0.0 2.1 1 1 1 2 2 2 1 AhpC/TSA antioxidant enzyme CBS PF00571.23 EMR64979.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 CBS domain Mito_fiss_reg PF05308.6 EMR64979.1 - 1.6 8.0 6.6 3.1 7.0 4.6 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator PCI PF01399.22 EMR64980.1 - 0.063 13.5 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 PCI domain HrpB1_HrpK PF09613.5 EMR64980.1 - 0.17 11.3 1.4 0.59 9.6 0.0 2.3 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) p450 PF00067.17 EMR64981.1 - 6.5e-48 163.3 0.0 5e-30 104.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF4452 PF14618.1 EMR64983.1 - 0.77 9.5 6.8 0.17 11.6 2.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4452) Methyltransf_12 PF08242.7 EMR64984.1 - 0.036 14.5 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMR64984.1 - 0.063 13.7 0.0 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EMR64984.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cu-oxidase_3 PF07732.10 EMR64985.1 - 2.5e-40 136.8 6.4 1.9e-37 127.6 1.1 3.9 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMR64985.1 - 6.7e-39 132.5 0.1 6.7e-39 132.5 0.1 3.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EMR64985.1 - 1.7e-36 125.4 1.2 8.2e-35 120.0 0.1 2.6 2 0 0 2 2 2 1 Multicopper oxidase FTR1 PF03239.9 EMR64986.1 - 9e-83 277.7 8.8 1.1e-82 277.4 6.1 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4231 PF14015.1 EMR64986.1 - 0.71 9.8 6.1 0.13 12.2 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Myb_DNA-bind_4 PF13837.1 EMR64988.1 - 5.3e-05 23.2 0.2 0.00021 21.3 0.0 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MSP1_C PF07462.6 EMR64988.1 - 0.07 11.5 2.8 0.083 11.2 1.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus HoxA13_N PF12284.3 EMR64988.1 - 0.73 9.9 4.9 1.1 9.3 3.4 1.3 1 0 0 1 1 1 0 Hox protein A13 N terminal DEC-1_N PF04625.8 EMR64988.1 - 6.2 5.3 11.3 8.4 4.9 7.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region NPDC1 PF06809.6 EMR64989.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) Saccharop_dh PF03435.13 EMR64991.1 - 1.5e-127 425.7 0.0 1.7e-127 425.5 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EMR64991.1 - 0.00016 21.7 0.1 0.00027 20.9 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EMR64991.1 - 0.00018 21.6 0.1 0.00028 21.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 EMR64991.1 - 0.016 14.5 0.2 0.067 12.5 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain GFO_IDH_MocA PF01408.17 EMR64991.1 - 0.035 14.6 0.1 0.064 13.7 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Mcp5_PH PF12814.2 EMR64992.1 - 1.3e-48 163.9 0.9 2.8e-48 162.8 0.0 2.1 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 EMR64992.1 - 0.0036 17.0 9.0 0.0036 17.0 6.2 2.3 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein DivIC PF04977.10 EMR64992.1 - 4.9 6.7 6.5 0.4 10.1 0.2 2.3 1 1 1 2 2 2 0 Septum formation initiator PALP PF00291.20 EMR64993.1 - 2.2e-08 33.7 0.3 3.6e-08 33.0 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme UQ_con PF00179.21 EMR64994.1 - 2.6e-36 124.1 0.0 3.4e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMR64994.1 - 0.0084 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMR64994.1 - 0.042 13.7 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 EMR64994.1 - 0.094 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain HAD_2 PF13419.1 EMR64995.1 - 1.4e-22 80.7 0.0 2.9e-22 79.7 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR64995.1 - 3e-09 37.6 0.0 4.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR64995.1 - 8e-06 25.4 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like IlvC PF01450.14 EMR64996.1 - 9.5e-46 155.3 0.0 1.3e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 EMR64996.1 - 2.2e-21 75.9 0.0 3.7e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NmrA PF05368.8 EMR64997.1 - 8.3e-63 211.7 0.0 1e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR64997.1 - 9.2e-13 48.5 0.0 1.4e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMR64997.1 - 1.3e-06 27.3 0.0 1.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EMR64997.1 - 0.0081 15.1 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase GMC_oxred_C PF05199.8 EMR64998.1 - 4.9e-27 94.9 0.0 5.4e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase p450 PF00067.17 EMR64999.1 - 3.4e-18 65.4 0.0 5.1e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EMR64999.1 - 1.3e-09 37.5 0.0 2.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EMR64999.1 - 0.0015 17.4 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein PIG-U PF06728.8 EMR65000.1 - 9.8e-123 409.7 29.9 1.1e-122 409.5 20.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.8 EMR65000.1 - 3.9e-05 23.4 0.4 3.9e-05 23.4 0.3 1.8 1 1 1 2 2 2 1 Mannosyltransferase (PIG-M) Peroxin-13_N PF04088.8 EMR65001.1 - 6.7e-57 191.8 0.0 9.3e-57 191.4 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EMR65001.1 - 3.7e-09 35.9 0.0 6.7e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMR65001.1 - 3.6e-08 32.8 0.1 6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMR65001.1 - 9.9e-08 31.2 0.0 1.9e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 SH3 domain Mito_fiss_reg PF05308.6 EMR65001.1 - 5.2 6.3 6.3 9 5.5 4.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Beta_elim_lyase PF01212.16 EMR65003.1 - 0.024 13.8 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase Prp19_bind PF06991.6 EMR65003.1 - 0.11 11.7 0.4 0.13 11.5 0.3 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Pkinase_Tyr PF07714.12 EMR65004.1 - 0.092 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase FAD_binding_4 PF01565.18 EMR65005.1 - 6.2e-21 74.3 1.0 1.4e-20 73.2 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR65005.1 - 7.2e-08 32.2 0.0 1.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Bax1-I PF01027.15 EMR65007.1 - 3.5e-31 108.4 11.4 5.1e-31 107.8 7.9 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Abhydrolase_6 PF12697.2 EMR65008.1 - 2.9e-20 73.1 0.1 3.8e-20 72.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR65008.1 - 1e-16 61.2 0.1 4.8e-16 59.0 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR65008.1 - 2e-07 30.8 0.0 6.5e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EMR65008.1 - 0.011 16.0 0.1 0.014 15.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S15 PF02129.13 EMR65008.1 - 0.025 14.0 0.0 0.044 13.1 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Fungal_trans PF04082.13 EMR65009.1 - 1.9e-11 43.3 0.5 3e-11 42.7 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EMR65011.1 - 4.4e-78 262.8 22.4 5.1e-78 262.6 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR65011.1 - 4.6e-29 101.2 49.7 4.7e-28 97.9 18.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2 PF04550.7 EMR65011.1 - 0.062 13.3 1.3 0.19 11.8 0.9 1.9 1 0 0 1 1 1 0 Phage holin family 2 DUF2401 PF10287.4 EMR65012.1 - 2.2e-74 249.9 0.1 3e-74 249.4 0.1 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EMR65012.1 - 7.2e-20 70.9 0.0 1.7e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Transp_cyt_pur PF02133.10 EMR65013.1 - 2e-40 138.7 36.0 2.2e-38 131.9 24.9 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ank_2 PF12796.2 EMR65014.1 - 4.3e-28 97.4 1.6 1.6e-16 60.4 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMR65014.1 - 9e-24 82.0 5.5 3.6e-06 26.4 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EMR65014.1 - 2.2e-19 69.4 0.3 9.2e-08 32.4 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) NACHT PF05729.7 EMR65014.1 - 4.4e-13 49.2 0.1 7.2e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.1 EMR65014.1 - 6.1e-12 45.3 0.3 3.5e-05 23.8 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR65014.1 - 5.4e-09 35.4 0.5 0.1 12.8 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat PNP_UDP_1 PF01048.15 EMR65014.1 - 4.7e-06 25.7 0.0 8.6e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 EMR65014.1 - 9.4e-05 22.4 0.1 0.00039 20.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EMR65014.1 - 0.00012 21.0 0.0 0.00023 20.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 EMR65014.1 - 0.00023 21.3 0.0 0.014 15.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EMR65014.1 - 0.0026 17.4 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EMR65014.1 - 0.0036 17.4 0.0 0.0079 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMR65014.1 - 0.0044 16.9 0.1 0.099 12.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain cNMP_binding PF00027.24 EMR65015.1 - 1.9e-20 72.4 0.0 4.2e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EMR65015.1 - 4.9e-16 56.9 3.8 0.055 13.5 0.0 7.7 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.28 EMR65015.1 - 1.2e-08 33.7 4.9 3.2 8.1 0.0 7.0 5 2 0 5 5 5 3 Leucine Rich Repeat LRR_8 PF13855.1 EMR65015.1 - 4e-06 26.4 0.1 0.75 9.5 0.0 4.5 3 1 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 EMR65015.1 - 2.7e-05 23.6 0.0 0.43 10.2 0.0 4.8 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EMR65015.1 - 0.00055 19.6 7.8 3.2 8.3 0.0 6.5 7 0 0 7 7 7 1 Leucine rich repeat F-box-like PF12937.2 EMR65015.1 - 0.024 14.3 0.5 0.086 12.5 0.3 2.0 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EMR65015.1 - 0.4 10.4 2.6 1.2 8.8 0.5 2.7 2 1 0 2 2 2 0 F-box domain RPE65 PF03055.10 EMR65016.1 - 7.1e-72 242.5 0.0 9e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Adenine_glyco PF03352.8 EMR65016.1 - 0.035 13.6 0.1 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyladenine glycosylase Epimerase PF01370.16 EMR65017.1 - 1.2e-10 41.2 0.1 1.9e-10 40.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR65017.1 - 1.2e-05 24.2 0.0 1.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMR65017.1 - 7.6e-05 22.7 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMR65017.1 - 0.00011 21.1 0.0 0.0007 18.5 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.8 EMR65017.1 - 0.043 13.0 0.1 0.24 10.6 0.1 2.0 1 1 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 EMR65017.1 - 0.048 12.5 0.6 0.4 9.5 0.1 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EMR65017.1 - 0.049 13.5 0.4 7.5 6.4 0.2 2.6 1 1 1 2 2 2 0 short chain dehydrogenase Fungal_trans PF04082.13 EMR65018.1 - 1.9e-19 69.5 0.1 4.1e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR65018.1 - 3.9e-08 33.0 9.9 7.6e-08 32.1 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 EMR65019.1 - 6.7e-08 32.7 0.5 1.2e-06 28.7 0.4 2.1 1 1 1 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EMR65019.1 - 2e-06 27.2 0.3 0.0028 16.9 0.2 2.2 1 1 1 2 2 2 2 NmrA-like family KR PF08659.5 EMR65019.1 - 0.00018 21.1 0.4 0.0003 20.5 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR65019.1 - 0.00082 19.3 0.3 0.0012 18.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EMR65019.1 - 0.0034 16.8 0.1 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EMR65019.1 - 0.0072 16.7 1.0 0.13 12.6 0.6 2.5 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EMR65019.1 - 0.024 13.3 0.1 0.042 12.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3842 PF12953.2 EMR65019.1 - 0.12 12.4 0.2 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) GMC_oxred_C PF05199.8 EMR65020.1 - 7.2e-22 78.2 0.0 1.2e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR65020.1 - 5.9e-16 58.4 0.0 1.1e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase TPR_11 PF13414.1 EMR65021.1 - 9.5e-15 54.0 2.1 2.3e-09 36.7 0.0 2.3 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EMR65021.1 - 4.4e-12 44.9 2.5 1.3e-05 24.7 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMR65021.1 - 7.2e-08 31.7 1.4 0.041 13.5 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMR65021.1 - 1.4e-07 31.4 1.7 4.9e-05 23.5 0.3 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMR65021.1 - 0.00013 21.7 3.9 0.019 14.7 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMR65021.1 - 0.0002 21.2 6.8 0.0049 16.7 5.0 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMR65021.1 - 0.00061 20.3 7.4 0.0014 19.2 0.8 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMR65021.1 - 0.0036 16.9 3.2 0.54 10.1 0.2 3.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMR65021.1 - 0.006 16.9 3.6 0.048 14.1 0.3 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMR65021.1 - 0.01 15.7 0.6 0.049 13.5 0.1 2.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 EMR65021.1 - 0.02 15.2 3.6 0.074 13.4 2.5 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat SET PF00856.23 EMR65021.1 - 0.053 13.8 0.0 0.15 12.3 0.0 1.7 2 1 0 2 2 2 0 SET domain TPR_17 PF13431.1 EMR65021.1 - 0.26 11.5 2.5 36 4.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ADH_zinc_N PF00107.21 EMR65022.1 - 1e-22 80.0 0.0 1.6e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR65022.1 - 2.2e-19 70.6 0.0 4e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR65022.1 - 1.1e-07 31.5 0.1 2.6e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PMSR PF01625.16 EMR65023.1 - 1.6e-57 193.7 0.1 1.9e-57 193.5 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase FAD_binding_3 PF01494.14 EMR65024.1 - 1e-17 64.2 0.7 5.8e-15 55.2 0.5 3.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMR65024.1 - 0.00094 19.1 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR65024.1 - 0.028 13.3 0.1 0.1 11.5 0.0 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.20 EMR65025.1 - 2e-13 50.5 0.0 2.8e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR65025.1 - 1.7e-05 24.6 0.0 3e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR65025.1 - 0.00014 21.6 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR65025.1 - 0.00035 20.0 0.0 0.00049 19.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR65025.1 - 0.0049 16.9 0.0 0.025 14.5 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EMR65025.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EMR65025.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 EMR65026.1 - 3.2e-20 73.3 0.2 5.7e-20 72.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMR65026.1 - 1.2e-19 70.1 1.0 1.8e-19 69.5 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR65026.1 - 7.1e-13 48.2 0.0 1.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ribosomal_S11 PF00411.14 EMR65026.1 - 0.075 13.2 0.3 1.7 8.8 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S11 DUF2306 PF10067.4 EMR65027.1 - 1.1e-13 51.1 7.7 1.1e-13 51.1 5.3 1.9 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) Hexokinase_2 PF03727.11 EMR65029.1 - 1.1e-77 260.5 0.0 1.7e-77 259.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EMR65029.1 - 4.4e-62 209.0 0.0 6.3e-62 208.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase FAM91_C PF14648.1 EMR65029.1 - 0.061 12.1 0.0 0.089 11.6 0.0 1.1 1 0 0 1 1 1 0 FAM91 C-terminus HET PF06985.6 EMR65030.1 - 4.3e-20 72.2 1.0 2.5e-16 60.0 0.1 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Peptidase_S8 PF00082.17 EMR65031.1 - 7.8e-44 149.9 0.0 3.8e-43 147.6 0.0 2.0 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EMR65031.1 - 5.2e-12 46.1 0.1 1.3e-11 44.8 0.1 1.8 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) ADH_N PF08240.7 EMR65032.1 - 1.7e-17 63.1 0.0 2.2e-16 59.5 0.0 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR65032.1 - 3.8e-12 45.8 1.2 9.4e-11 41.3 0.8 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR65032.1 - 0.0025 18.6 0.0 0.0053 17.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1353 PF07087.6 EMR65032.1 - 0.057 12.9 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) ADH_N_assoc PF13823.1 EMR65032.1 - 0.061 12.9 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated HNH_2 PF13391.1 EMR65033.1 - 1.3e-08 34.4 0.0 2.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Beta_helix PF13229.1 EMR65034.1 - 5.4e-09 35.9 13.7 8.6e-07 28.8 2.8 2.8 2 1 1 3 3 3 2 Right handed beta helix region Chondroitinas_B PF14592.1 EMR65034.1 - 0.00063 18.6 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Chondroitinase B DUF1565 PF07602.6 EMR65034.1 - 0.018 14.1 0.1 0.018 14.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1565) Glyco_hydro_47 PF01532.15 EMR65035.1 - 7.7e-163 542.3 0.7 9e-163 542.1 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Abhydrolase_4 PF08386.5 EMR65036.1 - 1.9e-22 79.0 0.0 3.9e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EMR65036.1 - 1.2e-06 28.2 0.1 0.17 11.4 0.0 3.2 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR65036.1 - 0.00062 19.7 0.1 0.0056 16.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pescadillo_N PF06732.6 EMR65037.1 - 1.5e-113 378.7 0.1 1.5e-113 378.7 0.1 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EMR65037.1 - 2.3e-09 37.2 0.0 1.1e-08 35.0 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Flavodoxin_5 PF12724.2 EMR65037.1 - 0.011 15.6 1.3 0.026 14.5 0.9 1.5 1 0 0 1 1 1 0 Flavodoxin domain EBV-NA3 PF05009.7 EMR65037.1 - 0.85 8.8 4.4 2.1 7.5 3.1 1.6 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) GMC_oxred_N PF00732.14 EMR65038.1 - 4.5e-14 52.3 0.1 2.5e-12 46.5 0.0 2.4 1 1 0 1 1 1 1 GMC oxidoreductase Abhydrolase_3 PF07859.8 EMR65040.1 - 3.3e-27 95.4 0.1 2.4e-22 79.5 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMR65040.1 - 0.038 13.1 0.0 0.088 12.0 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Glyco_hydro_16 PF00722.16 EMR65041.1 - 4.8e-16 58.5 1.8 1e-15 57.5 1.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EMR65041.1 - 0.011 13.9 2.9 0.047 11.8 0.1 2.1 2 0 0 2 2 2 0 Beta-glucan synthesis-associated protein (SKN1) Pyr_redox_3 PF13738.1 EMR65042.1 - 9.5e-25 87.8 0.0 1.9e-23 83.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR65042.1 - 3.7e-07 30.0 0.0 4.4e-06 26.6 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMR65042.1 - 0.00045 20.0 0.1 0.041 13.6 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMR65042.1 - 0.00073 18.5 0.0 0.022 13.6 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EMR65042.1 - 0.0032 17.5 0.0 0.024 14.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EMR65042.1 - 0.0091 15.8 0.0 5.9 6.7 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EMR65043.1 - 3.9e-43 147.5 23.5 3.9e-43 147.5 16.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EMR65043.1 - 0.0012 17.0 0.7 0.0012 17.0 0.5 2.6 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family AP_endonuc_2 PF01261.19 EMR65044.1 - 6.3e-32 110.5 0.1 8.4e-32 110.1 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SOBP PF15279.1 EMR65044.1 - 0.77 10.0 4.1 1.1 9.5 2.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Cellulase PF00150.13 EMR65046.1 - 1.4e-48 165.5 0.8 1.9e-48 165.1 0.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.11 EMR65048.1 - 7.5e-07 28.1 9.8 1e-06 27.7 6.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TENA_THI-4 PF03070.11 EMR65049.1 - 5.6e-12 45.8 0.5 2.5e-06 27.4 0.0 2.4 2 1 0 2 2 2 2 TENA/THI-4/PQQC family Glyco_hydro_3 PF00933.16 EMR65050.1 - 1.5e-51 175.1 0.0 1.8e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR65050.1 - 5.5e-10 39.1 0.3 4.8e-09 36.0 0.0 2.1 1 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain OCD_Mu_crystall PF02423.10 EMR65051.1 - 4.7e-18 65.0 0.0 1e-17 63.9 0.0 1.6 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EMR65051.1 - 7.2e-07 29.3 0.1 2.1e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase PA14_2 PF10528.4 EMR65052.1 - 2e-11 43.8 0.1 3.1e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.7 EMR65052.1 - 2.6e-07 30.3 0.0 3.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 PA14 domain HhH-GPD PF00730.20 EMR65053.1 - 6.7e-11 42.4 0.0 1.4e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EMR65053.1 - 0.0014 18.1 0.0 0.0036 16.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Adeno_VII PF03228.9 EMR65053.1 - 0.017 15.6 0.2 0.067 13.7 0.4 1.7 2 0 0 2 2 2 0 Adenoviral core protein VII Aldo_ket_red PF00248.16 EMR65054.1 - 5.4e-30 104.1 0.0 1.3e-18 66.8 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family Proteasom_Rpn13 PF04683.8 EMR65054.1 - 0.026 14.5 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Proteasome complex subunit Rpn13 ubiquitin receptor PrpF PF04303.8 EMR65055.1 - 3.5e-18 65.4 0.5 3.2e-15 55.7 0.3 3.5 2 1 0 2 2 2 2 PrpF protein Mad3_BUB1_I PF08311.7 EMR65056.1 - 2.8e-42 143.4 0.1 3.8e-42 143.0 0.1 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EMR65057.1 - 1.4e-11 44.0 0.0 4.4e-11 42.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR65057.1 - 0.018 14.0 0.0 0.17 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase SDA1 PF05285.7 EMR65057.1 - 3 7.0 14.2 6.2 6.0 9.8 1.5 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 EMR65057.1 - 9 5.2 13.7 14 4.5 9.5 1.3 1 0 0 1 1 1 0 BUD22 7tm_2 PF00002.19 EMR65058.1 - 1.6e-10 40.5 12.8 9.1e-10 38.0 8.5 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 EMR65058.1 - 1.1e-07 31.2 0.0 2.5e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EMR65058.1 - 1.1e-06 27.8 11.7 1.9e-06 27.0 8.1 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EMR65058.1 - 1.7e-05 24.4 11.0 2.9e-05 23.7 7.6 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EMR65058.1 - 0.011 15.5 1.4 0.18 11.5 0.0 2.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term HCV_NS5a PF01506.14 EMR65058.1 - 1.8 8.3 7.7 1.2 8.9 0.2 2.6 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor polyprenyl_synt PF00348.12 EMR65059.1 - 6.5e-39 133.3 0.1 7.8e-39 133.0 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DRMBL PF07522.9 EMR65060.1 - 4.6e-30 103.8 0.0 1e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EMR65060.1 - 9e-11 41.6 0.0 2.4e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sugar_tr PF00083.19 EMR65062.1 - 6.9e-20 71.0 24.6 1.8e-17 63.0 17.0 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2686 PF10887.3 EMR65062.1 - 0.024 13.3 0.0 0.041 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) DUF2333 PF10095.4 EMR65062.1 - 0.026 13.1 0.0 0.046 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Fungal_trans PF04082.13 EMR65063.1 - 2.8e-10 39.5 0.0 5e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EMR65065.1 - 1.8e-34 119.0 24.1 2e-34 118.8 16.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily ADH_N PF08240.7 EMR65068.1 - 2.8e-28 97.8 2.1 8.4e-28 96.3 1.5 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR65068.1 - 4.9e-18 64.9 0.4 1e-17 63.9 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMR65068.1 - 0.039 13.3 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EMR65068.1 - 0.082 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.1 EMR65068.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-U1 PF06220.7 EMR65069.1 - 6.7e-22 76.7 3.4 9.9e-22 76.2 2.3 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EMR65069.1 - 0.025 14.7 3.5 0.051 13.7 2.4 1.5 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding adh_short PF00106.20 EMR65071.1 - 1.4e-11 44.5 0.0 2.2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR65071.1 - 0.00023 20.8 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR65071.1 - 0.002 17.9 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase tRNA-synt_2 PF00152.15 EMR65072.1 - 1.8e-79 266.9 0.1 2.5e-79 266.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EMR65072.1 - 3.5e-20 72.0 0.0 5.3e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EMR65072.1 - 1.9e-08 34.0 0.0 4.7e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMR65072.1 - 0.015 14.5 0.1 2.9 7.0 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) SGL PF08450.7 EMR65073.1 - 0.00062 19.2 2.5 0.0069 15.7 0.9 2.5 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region GDPD PF03009.12 EMR65074.1 - 4.5e-35 121.3 0.0 1.1e-33 116.8 0.0 2.1 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EMR65074.1 - 0.00026 21.0 0.5 0.0034 17.5 0.4 2.4 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family EMP24_GP25L PF01105.19 EMR65075.1 - 3.8e-41 140.8 0.0 4.3e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MBF1 PF08523.5 EMR65076.1 - 1e-22 79.8 2.3 2.1e-22 78.9 1.6 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EMR65076.1 - 1.2e-08 34.6 0.1 1.9e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EMR65076.1 - 2.3e-07 30.8 0.0 4.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EMR65076.1 - 0.00094 19.1 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4604 PF15377.1 EMR65077.1 - 0.0085 16.3 0.0 0.012 15.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Nucleopor_Nup85 PF07575.8 EMR65078.1 - 0.00016 20.0 1.3 0.00055 18.2 0.0 2.4 3 1 0 3 3 3 1 Nup85 Nucleoporin eIF3_p135 PF12807.2 EMR65078.1 - 0.0059 16.5 1.0 0.015 15.2 0.7 1.7 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 Leader_Trp PF08255.6 EMR65078.1 - 0.05 13.2 0.3 0.19 11.4 0.2 2.0 1 0 0 1 1 1 0 Trp-operon Leader Peptide Daxx PF03344.10 EMR65078.1 - 9.9 4.5 19.9 16 3.8 13.8 1.2 1 0 0 1 1 1 0 Daxx Family PIG-F PF06699.6 EMR65079.1 - 3.8e-54 183.5 1.4 5.6e-54 182.9 1.0 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Translin PF01997.11 EMR65079.1 - 4.6e-35 121.0 0.2 6.3e-35 120.5 0.1 1.1 1 0 0 1 1 1 1 Translin family DUF1616 PF07760.6 EMR65079.1 - 0.045 12.8 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF1993 PF09351.5 EMR65080.1 - 1.1e-35 122.9 0.0 1.3e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) VBS PF08913.5 EMR65080.1 - 0.073 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Vinculin Binding Site WxL PF13731.1 EMR65080.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 WxL domain surface cell wall-binding TPR_19 PF14559.1 EMR65080.1 - 0.18 12.1 3.0 4.5 7.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Sdh5 PF03937.11 EMR65081.1 - 1e-21 76.3 0.1 1.9e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase 7tm_2 PF00002.19 EMR65082.1 - 0.014 14.4 0.9 0.024 13.7 0.7 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Transthyretin PF00576.16 EMR65083.1 - 2.6e-26 91.6 0.5 2.8e-16 59.3 0.3 2.0 1 1 1 2 2 2 2 HIUase/Transthyretin family Saccharop_dh PF03435.13 EMR65084.1 - 7.4e-87 291.8 0.0 5.8e-85 285.5 0.0 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EMR65084.1 - 6.3e-08 32.7 0.1 1.3e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EMR65084.1 - 6.7e-05 23.2 0.1 0.00014 22.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EMR65084.1 - 0.048 13.9 0.1 0.089 13.1 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EMR65084.1 - 0.055 13.7 0.1 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_3 PF03447.11 EMR65084.1 - 0.11 12.9 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain adh_short PF00106.20 EMR65086.1 - 2.9e-13 50.0 0.0 4.7e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMR65086.1 - 7.5e-06 26.0 0.1 1.7e-05 24.9 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR65086.1 - 0.00067 19.1 0.0 0.0012 18.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EMR65086.1 - 0.0042 16.7 0.0 0.0086 15.7 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR65086.1 - 0.014 15.1 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EMR65086.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EMR65086.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EMR65086.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Aft1_HRR PF11787.3 EMR65087.1 - 1.6e-15 57.9 6.0 1.6e-15 57.9 4.2 3.5 3 1 1 4 4 4 1 Aft1 HRR domain bZIP_1 PF00170.16 EMR65087.1 - 7.3e-14 51.4 6.5 1.2e-13 50.8 4.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMR65087.1 - 2.3e-07 30.5 6.2 4.5e-07 29.5 4.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMR65087.1 - 0.00053 20.2 2.7 0.00053 20.2 1.9 2.1 3 0 0 3 3 3 1 bZIP Maf transcription factor Macoilin PF09726.4 EMR65087.1 - 0.24 9.6 10.0 0.27 9.4 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF334 PF03904.8 EMR65087.1 - 0.27 10.5 1.9 0.41 9.9 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) NpwBP PF12622.2 EMR65087.1 - 0.44 11.0 6.6 0.35 11.3 1.1 2.8 2 0 0 2 2 2 0 mRNA biogenesis factor Abhydrolase_3 PF07859.8 EMR65088.1 - 3e-42 144.5 0.0 3.8e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMR65088.1 - 1.1e-08 34.2 0.1 2.3e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EMR65088.1 - 0.00023 20.9 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMR65088.1 - 0.057 12.8 0.1 0.31 10.4 0.1 1.9 1 1 0 1 1 1 0 Putative esterase DUF2424 PF10340.4 EMR65088.1 - 0.12 11.0 0.0 0.31 9.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Ctr PF04145.10 EMR65089.1 - 2.5e-19 69.7 1.4 5.5e-19 68.6 1.0 1.6 1 1 0 1 1 1 1 Ctr copper transporter family PAP2 PF01569.16 EMR65089.1 - 4.2 7.0 6.9 37 4.0 4.8 2.1 1 1 0 1 1 1 0 PAP2 superfamily PNP_UDP_1 PF01048.15 EMR65090.1 - 2.1e-14 53.0 0.2 3.1e-14 52.5 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 EMR65090.1 - 3.9e-09 36.3 0.3 7.4e-09 35.4 0.2 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMR65090.1 - 2e-05 24.6 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMR65090.1 - 0.00044 20.3 0.0 0.00087 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EMR65090.1 - 0.0024 17.3 0.6 0.0063 16.0 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EMR65090.1 - 0.0095 16.2 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EMR65090.1 - 0.014 16.2 0.0 0.075 13.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EMR65090.1 - 0.019 15.2 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EMR65090.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 EMR65090.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMR65090.1 - 0.16 12.1 0.2 0.63 10.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase DUF258 PF03193.11 EMR65090.1 - 0.17 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ferric_reduct PF01794.14 EMR65091.1 - 1.9e-12 47.3 14.6 1.9e-12 47.3 10.1 2.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EMR65091.1 - 9.1e-11 41.9 0.0 1.3e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMR65091.1 - 4.2e-09 36.2 0.0 9.1e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain CoA_trans PF01144.18 EMR65091.1 - 0.028 13.6 0.1 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase Pox_Ag35 PF03286.9 EMR65092.1 - 5.8 6.3 9.9 11 5.4 6.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 EMR65092.1 - 8.1 4.3 9.2 12 3.7 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein PTPA PF03095.10 EMR65093.1 - 5.7e-84 281.8 1.9 6.7e-84 281.5 1.3 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RNase_PH PF01138.16 EMR65094.1 - 8.6e-13 48.7 0.0 2e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EMR65094.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 HrpF PF06266.7 EMR65094.1 - 0.069 13.2 0.5 1.2 9.3 0.1 2.3 1 1 1 2 2 2 0 HrpF protein Anp1 PF03452.9 EMR65095.1 - 7.3e-108 359.8 0.0 9.1e-108 359.4 0.0 1.0 1 0 0 1 1 1 1 Anp1 DUF3357 PF11837.3 EMR65095.1 - 0.032 14.0 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Glycos_transf_2 PF00535.21 EMR65095.1 - 0.055 13.1 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 NAD_kinase PF01513.16 EMR65096.1 - 7.1e-72 241.5 0.0 9.7e-72 241.1 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Aldedh PF00171.17 EMR65098.1 - 5.1e-137 456.9 0.0 6e-137 456.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMR65098.1 - 0.001 17.9 0.0 0.0022 16.7 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) VWA_2 PF13519.1 EMR65099.1 - 0.00058 20.0 0.0 0.005 16.9 0.0 1.9 1 1 1 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EMR65099.1 - 0.0027 17.4 0.0 0.0061 16.2 0.0 1.6 1 1 1 2 2 2 1 von Willebrand factor type A domain Glycos_transf_2 PF00535.21 EMR65099.1 - 0.077 12.6 0.3 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 Peptidase_S10 PF00450.17 EMR65100.1 - 8.2e-82 275.5 1.5 9.9e-81 272.0 1.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase Ald_Xan_dh_C2 PF02738.13 EMR65101.1 - 1e-185 618.2 0.0 1.4e-185 617.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EMR65101.1 - 9.1e-50 168.4 0.0 1.6e-49 167.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 EMR65101.1 - 1.4e-30 105.6 0.0 3e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EMR65101.1 - 7.8e-29 99.3 0.0 1.6e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.12 EMR65101.1 - 2e-28 98.3 0.1 8.2e-28 96.3 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.22 EMR65101.1 - 6.2e-08 32.2 1.9 7.7e-08 31.9 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain EBP PF05241.7 EMR65101.1 - 0.19 10.7 0.1 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Emopamil binding protein PPR_2 PF13041.1 EMR65102.1 - 6.1e-16 58.1 0.0 8.7e-05 22.4 0.0 4.8 4 1 1 5 5 5 4 PPR repeat family PPR_3 PF13812.1 EMR65102.1 - 9.9e-16 56.6 0.4 0.00066 19.7 0.0 6.0 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.15 EMR65102.1 - 1.2e-13 49.9 4.0 7.4e-05 22.4 0.0 4.9 4 1 0 4 4 4 2 PPR repeat PPR_1 PF12854.2 EMR65102.1 - 6.2e-09 35.1 0.7 0.035 13.6 0.0 3.8 3 1 0 3 3 3 3 PPR repeat PSDC PF12588.3 EMR65103.1 - 3.1e-29 101.3 0.1 6.3e-29 100.3 0.1 1.5 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EMR65103.1 - 2.9e-20 72.4 0.0 4.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase AIP3 PF03915.8 EMR65103.1 - 0.082 11.8 0.0 0.2 10.5 0.0 1.6 1 0 0 1 1 1 0 Actin interacting protein 3 MRP-S25 PF13741.1 EMR65104.1 - 7.5e-74 248.0 8.7 1.4e-71 240.6 6.0 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 EMR65104.1 - 7.5e-06 25.8 3.3 3.4e-05 23.7 2.3 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 RNase_H2-Ydr279 PF09468.5 EMR65105.1 - 0.0088 15.2 0.7 0.0094 15.1 0.5 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Cullin PF00888.17 EMR65106.1 - 6.6e-50 170.2 0.0 1.3e-49 169.2 0.0 1.4 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 EMR65106.1 - 2.5e-20 72.4 0.0 4.8e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.5 EMR65106.1 - 0.018 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator RasGEF_N PF00618.15 EMR65106.1 - 0.039 14.0 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 RasGEF N-terminal motif Csm1 PF12539.3 EMR65107.1 - 8.2e-26 90.3 0.2 3.8e-25 88.1 0.0 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 Taxilin PF09728.4 EMR65107.1 - 0.00098 18.2 7.5 0.0017 17.5 5.2 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Filament PF00038.16 EMR65107.1 - 0.0024 17.4 10.2 0.0054 16.2 7.1 1.6 1 0 0 1 1 1 1 Intermediate filament protein BBP1_C PF15272.1 EMR65107.1 - 0.01 15.3 5.7 0.02 14.4 3.9 1.5 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal IncA PF04156.9 EMR65107.1 - 0.052 13.1 15.8 0.086 12.4 9.5 2.1 1 1 1 2 2 2 0 IncA protein Rootletin PF15035.1 EMR65107.1 - 0.082 12.8 13.0 0.22 11.5 9.0 1.7 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF342 PF03961.8 EMR65107.1 - 0.084 11.2 4.1 0.16 10.3 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MMPL PF03176.10 EMR65107.1 - 0.1 11.3 7.5 0.16 10.6 5.2 1.2 1 0 0 1 1 1 0 MMPL family TPR_MLP1_2 PF07926.7 EMR65107.1 - 0.11 12.2 20.3 0.47 10.1 14.1 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3571 PF12095.3 EMR65107.1 - 0.12 12.6 5.2 0.29 11.3 3.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3571) Reo_sigmaC PF04582.7 EMR65107.1 - 0.13 11.4 2.0 0.2 10.8 1.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3138 PF11336.3 EMR65107.1 - 0.14 10.2 11.4 0.22 9.6 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spc7 PF08317.6 EMR65107.1 - 0.15 10.6 9.3 0.24 9.9 6.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 EMR65107.1 - 0.25 9.1 3.4 0.34 8.7 2.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bap31 PF05529.7 EMR65107.1 - 0.3 10.5 8.6 0.73 9.2 6.0 1.7 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Atg14 PF10186.4 EMR65107.1 - 0.39 9.6 11.1 0.66 8.8 7.7 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 EMR65107.1 - 0.82 8.0 8.0 1.4 7.3 5.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family 5_nucleotid PF05761.9 EMR65107.1 - 1.9 6.8 4.7 3 6.2 3.3 1.2 1 0 0 1 1 1 0 5' nucleotidase family CDC37_N PF03234.9 EMR65107.1 - 2.4 8.4 10.1 3.4 7.9 6.4 1.8 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding APG6 PF04111.7 EMR65107.1 - 2.6 7.0 13.2 4.4 6.2 9.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EMR65107.1 - 6.2 7.2 11.0 1.5 9.2 2.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APH PF01636.18 EMR65108.1 - 5.2e-40 137.6 4.0 5.2e-40 137.6 2.7 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMR65108.1 - 1e-06 28.1 0.2 3.7e-06 26.2 0.0 2.0 2 1 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.15 EMR65108.1 - 0.023 14.2 0.0 0.053 13.0 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase OAD_gamma PF04277.8 EMR65108.1 - 2.2 8.7 4.1 1.3e+02 2.9 0.0 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Cys_Met_Meta_PP PF01053.15 EMR65109.1 - 1.6e-134 448.0 0.0 1.9e-134 447.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EMR65109.1 - 4.3e-06 25.7 0.0 2.2e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 EMR65109.1 - 1.9e-05 23.1 0.1 5.2e-05 21.7 0.1 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.12 EMR65109.1 - 0.00023 20.3 0.1 0.00072 18.6 0.0 1.8 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EMR65109.1 - 0.0015 17.7 0.0 0.0042 16.2 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase AAA PF00004.24 EMR65110.1 - 2.2e-38 131.4 0.0 3.5e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMR65110.1 - 2.6e-06 27.5 0.1 0.00011 22.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EMR65110.1 - 3.4e-06 26.9 0.0 6.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMR65110.1 - 5e-06 26.6 0.1 0.00019 21.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMR65110.1 - 1.1e-05 24.6 0.0 1.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EMR65110.1 - 1.5e-05 24.7 0.1 0.00016 21.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMR65110.1 - 3.8e-05 24.4 0.0 8.7e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EMR65110.1 - 4.7e-05 23.3 0.0 8.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EMR65110.1 - 0.00061 19.6 0.0 0.0014 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMR65110.1 - 0.00071 18.7 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EMR65110.1 - 0.00074 19.2 0.2 0.0043 16.7 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 EMR65110.1 - 0.00084 18.5 0.1 0.0018 17.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EMR65110.1 - 0.00089 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 EMR65110.1 - 0.0016 18.4 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EMR65110.1 - 0.0018 17.7 1.4 0.063 12.6 0.1 2.7 2 1 1 3 3 3 1 AAA domain NACHT PF05729.7 EMR65110.1 - 0.0024 17.5 0.1 0.011 15.4 0.0 2.1 2 1 1 3 3 3 1 NACHT domain RNA_helicase PF00910.17 EMR65110.1 - 0.0031 17.6 0.0 0.0076 16.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.17 EMR65110.1 - 0.0081 15.0 0.0 0.046 12.5 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain Sigma54_activat PF00158.21 EMR65110.1 - 0.0084 15.5 0.0 0.022 14.2 0.0 1.6 2 0 0 2 2 1 1 Sigma-54 interaction domain Oxidored_nitro PF00148.14 EMR65110.1 - 0.01 14.4 0.0 0.064 11.8 0.0 2.0 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase AAA_24 PF13479.1 EMR65110.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EMR65110.1 - 0.014 14.3 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 EMR65110.1 - 0.015 15.2 0.1 0.033 14.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 EMR65110.1 - 0.019 14.6 0.0 0.11 12.1 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase Bac_DnaA PF00308.13 EMR65110.1 - 0.023 14.3 0.0 0.052 13.1 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein TIP49 PF06068.8 EMR65110.1 - 0.024 13.3 0.1 0.08 11.6 0.0 1.9 2 0 0 2 2 2 0 TIP49 C-terminus AAA_18 PF13238.1 EMR65110.1 - 0.03 14.6 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EMR65110.1 - 0.032 13.8 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMR65110.1 - 0.048 13.9 0.0 0.1 12.8 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.12 EMR65110.1 - 0.079 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EMR65110.1 - 0.093 12.3 0.0 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 EMR65110.1 - 0.1 11.2 0.0 0.17 10.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 EMR65110.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase P34-Arc PF04045.9 EMR65111.1 - 9.7e-103 342.6 0.8 1.2e-102 342.3 0.6 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Radical_SAM PF04055.16 EMR65111.1 - 0.072 13.2 0.0 0.46 10.6 0.0 2.0 2 1 0 2 2 2 0 Radical SAM superfamily WD40 PF00400.27 EMR65112.1 - 8.2e-70 228.4 19.1 2.2e-09 36.8 0.1 11.5 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp12 PF04003.7 EMR65112.1 - 3.9e-19 68.5 1.6 6.5e-19 67.8 1.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EMR65112.1 - 7e-06 24.4 9.1 7.4e-05 21.0 0.4 4.6 3 1 1 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EMR65112.1 - 0.00054 18.8 7.0 1.2 7.8 0.1 5.7 3 1 1 6 6 6 2 Nup133 N terminal like DUF4243 PF14027.1 EMR65113.1 - 5.4e-80 269.2 0.0 6.6e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) zf-C2H2_4 PF13894.1 EMR65114.1 - 0.0002 21.4 4.2 0.075 13.3 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMR65114.1 - 0.0022 18.2 6.9 0.12 12.8 0.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMR65114.1 - 0.0047 17.1 0.4 0.13 12.6 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EMR65114.1 - 0.026 14.4 1.3 5.6 7.0 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.1 EMR65114.1 - 0.069 12.3 0.3 0.14 11.4 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EMR65114.1 - 2.3 8.2 4.8 0.65 9.9 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain SMC_N PF02463.14 EMR65115.1 - 3.4e-70 235.6 32.2 2.8e-69 232.6 22.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EMR65115.1 - 2.2e-27 95.4 0.1 1.3e-26 92.8 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EMR65115.1 - 1.4e-12 48.2 6.5 1.8e-05 24.8 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EMR65115.1 - 3e-10 40.7 3.5 3e-10 40.7 2.5 6.5 2 2 1 3 3 1 1 AAA domain Reo_sigmaC PF04582.7 EMR65115.1 - 0.00023 20.4 1.6 0.00023 20.4 1.1 4.9 3 2 2 6 6 6 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 EMR65115.1 - 0.00032 20.1 0.0 0.00065 19.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IncA PF04156.9 EMR65115.1 - 0.003 17.1 12.4 0.003 17.1 8.6 8.3 3 2 5 8 8 8 4 IncA protein DivIC PF04977.10 EMR65115.1 - 0.0031 16.9 2.7 0.0031 16.9 1.9 11.6 7 3 6 13 13 12 1 Septum formation initiator Laminin_II PF06009.7 EMR65115.1 - 0.0038 17.0 2.2 0.0038 17.0 1.5 9.0 3 2 6 9 9 8 2 Laminin Domain II Tropomyosin_1 PF12718.2 EMR65115.1 - 0.006 16.4 20.5 0.006 16.4 14.2 9.0 4 3 3 8 8 6 1 Tropomyosin like DUF4164 PF13747.1 EMR65115.1 - 0.0088 16.1 0.6 0.0088 16.1 0.4 8.2 6 2 3 10 10 9 2 Domain of unknown function (DUF4164) Ribosomal_S26e PF01283.14 EMR65116.1 - 1.2e-50 170.5 9.9 1.4e-50 170.3 6.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 EMR65116.1 - 0.041 14.2 1.0 1.2 9.6 0.4 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Zn_ribbon_2 PF12674.2 EMR65116.1 - 0.077 13.3 0.3 7.8 6.9 0.0 2.3 1 1 1 2 2 2 0 Putative zinc ribbon domain DUF1918 PF08940.6 EMR65116.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Isochorismatase PF00857.15 EMR65117.1 - 1.8e-31 109.4 0.0 4.5e-31 108.1 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family ubiquitin PF00240.18 EMR65118.1 - 1.6e-34 117.1 0.9 2.7e-34 116.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EMR65118.1 - 3.7e-28 97.0 2.1 7.5e-28 96.1 1.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EMR65118.1 - 5.8e-20 70.7 0.7 1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMR65118.1 - 8.4e-06 25.9 0.2 3.9e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EMR65118.1 - 0.00012 21.7 0.1 0.00019 21.1 0.0 1.3 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EMR65118.1 - 0.00069 19.4 0.7 0.0015 18.4 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMR65118.1 - 0.004 17.3 0.4 0.0055 16.8 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EMR65118.1 - 0.057 13.4 0.7 0.1 12.6 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EMR65118.1 - 0.087 11.1 2.4 2.2 6.5 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain ELYS PF13934.1 EMR65119.1 - 1.5e-55 188.3 0.5 1.8e-55 188.1 0.4 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly DUF2489 PF10675.4 EMR65119.1 - 0.0078 15.8 1.3 0.049 13.3 1.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2489) Terpene_synth_C PF03936.11 EMR65120.1 - 0.00024 20.4 0.0 0.00028 20.2 0.0 1.0 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain FAD_binding_3 PF01494.14 EMR65121.1 - 1.3e-69 234.9 2.3 6e-69 232.7 1.6 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EMR65121.1 - 0.023 14.7 0.5 0.092 12.7 0.4 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EMR65121.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Nop PF01798.13 EMR65122.1 - 4.5e-57 191.5 0.1 9.5e-57 190.5 0.1 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOP5NT PF08156.8 EMR65122.1 - 4e-21 74.9 0.3 4e-21 74.9 0.2 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain NOSIC PF08060.8 EMR65122.1 - 2.2e-20 72.2 0.0 4.5e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain RNA_polI_A34 PF08208.6 EMR65122.1 - 0.24 11.0 18.4 0.5 10.0 12.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 EMR65122.1 - 0.97 9.3 8.4 1.7 8.5 5.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family adh_short PF00106.20 EMR65123.1 - 9.5e-29 100.4 0.9 1.3e-28 100.0 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR65123.1 - 1.2e-13 51.1 0.5 1.7e-13 50.6 0.3 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR65123.1 - 3.7e-12 46.5 0.0 5e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR65123.1 - 1.6e-05 24.4 0.1 0.00012 21.5 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMR65123.1 - 1.7e-05 23.8 0.4 2.1e-05 23.6 0.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EMR65123.1 - 0.0039 17.3 0.1 0.007 16.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EMR65123.1 - 0.015 15.3 0.3 0.024 14.6 0.2 1.5 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EMR65123.1 - 0.038 13.7 0.1 0.079 12.7 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Med16 PF11635.3 EMR65123.1 - 0.066 11.1 0.0 0.084 10.8 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 CW_binding_2 PF04122.7 EMR65123.1 - 0.14 12.3 0.6 0.29 11.3 0.4 1.5 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 NAD_binding_6 PF08030.7 EMR65124.1 - 0.0054 16.6 0.0 0.0066 16.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain p450 PF00067.17 EMR65125.1 - 3.2e-41 141.3 0.0 4.5e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pneumo_att_G PF05539.6 EMR65126.1 - 1.3 8.3 5.3 1.5 8.1 3.7 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Chorion_2 PF03964.10 EMR65126.1 - 3.9 8.0 10.5 8.7 6.9 7.3 1.6 1 1 0 1 1 1 0 Chorion family 2 SLD3 PF08639.5 EMR65127.1 - 5.1e-54 183.7 6.3 6.1e-54 183.4 4.3 1.1 1 0 0 1 1 1 1 DNA replication regulator SLD3 CDK5_activator PF03261.10 EMR65127.1 - 1.1 8.5 8.1 1.8 7.8 5.6 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein MFS_1 PF07690.11 EMR65128.1 - 3.8e-25 88.3 35.0 5.6e-25 87.7 24.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR65128.1 - 7.6e-10 37.9 14.8 7.6e-10 37.9 10.3 2.6 2 1 0 3 3 3 2 Sugar (and other) transporter TMEM192 PF14802.1 EMR65128.1 - 1.3 7.8 3.4 3.4 6.4 1.3 2.1 2 0 0 2 2 2 0 TMEM192 family DUF1072 PF06380.6 EMR65128.1 - 1.5 8.5 5.5 1.8 8.2 1.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) PFK PF00365.15 EMR65129.1 - 1.4e-163 542.5 0.2 2.5e-118 394.1 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase PRF PF06875.6 EMR65129.1 - 0.16 11.1 0.1 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF BRCT PF00533.21 EMR65130.1 - 0.00019 21.5 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain ArsA_ATPase PF02374.10 EMR65130.1 - 0.42 9.6 2.0 0.75 8.7 1.4 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase Sigma70_ner PF04546.8 EMR65130.1 - 1.7 8.1 12.2 0.058 13.0 3.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2890 PF11081.3 EMR65130.1 - 3.5 7.6 13.9 0.092 12.8 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Troponin-I_N PF11636.3 EMR65130.1 - 8 6.2 9.6 8.8 6.1 3.2 2.7 2 0 0 2 2 2 0 Troponin I residues 1-32 DUF1510 PF07423.6 EMR65130.1 - 9.2 5.5 12.7 0.43 9.8 4.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) p450 PF00067.17 EMR65131.1 - 1.1e-44 152.7 0.0 1.5e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 VPS11_C PF12451.3 EMR65131.1 - 0.0059 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal KR PF08659.5 EMR65132.1 - 5.2e-52 176.1 0.2 9.6e-52 175.2 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR65132.1 - 1.5e-40 138.8 0.1 4.1e-40 137.4 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EMR65132.1 - 1.3e-16 60.3 0.0 4e-16 58.7 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMR65132.1 - 4.2e-16 59.2 0.0 1.3e-15 57.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR65132.1 - 7.3e-13 48.5 0.0 1.6e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EMR65132.1 - 3.1e-12 47.4 0.0 1.5e-11 45.2 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EMR65132.1 - 1.7e-08 34.5 0.2 6.6e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EMR65132.1 - 2.2e-08 34.6 0.0 4.1e-07 30.5 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR65132.1 - 6.9e-07 28.9 0.0 3.5e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR65132.1 - 1e-06 29.1 0.0 3.9e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 EMR65132.1 - 0.00016 21.2 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase ADH_N PF08240.7 EMR65132.1 - 0.00041 20.0 0.0 0.0014 18.3 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NmrA PF05368.8 EMR65132.1 - 0.041 13.1 0.1 0.25 10.5 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Ubie_methyltran PF01209.13 EMR65132.1 - 0.098 11.7 0.0 0.36 9.8 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family YqzL PF14006.1 EMR65133.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 YqzL-like protein Serglycin PF04360.7 EMR65133.1 - 1.3 8.7 4.7 5 6.8 2.7 2.2 2 0 0 2 2 2 0 Serglycin ketoacyl-synt PF00109.21 EMR65134.1 - 2e-66 224.0 0.0 3.5e-66 223.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMR65134.1 - 5.4e-51 173.8 0.1 9e-51 173.0 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EMR65134.1 - 9.4e-41 138.3 0.0 2.2e-40 137.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EMR65134.1 - 0.0036 16.3 0.0 0.0071 15.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EMR65134.1 - 0.0044 16.6 0.8 0.0084 15.7 0.1 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III BPD_transp_1 PF00528.17 EMR65135.1 - 0.0026 17.2 2.7 0.0046 16.4 1.7 1.5 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component CytB6-F_Fe-S PF08802.5 EMR65135.1 - 0.024 14.6 0.9 0.089 12.8 0.6 2.0 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit ADH_zinc_N PF00107.21 EMR65137.1 - 4.5e-25 87.6 0.1 8e-25 86.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR65137.1 - 6.4e-13 49.7 0.0 1.3e-12 48.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR65137.1 - 4e-08 32.9 0.0 1.5e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EMR65137.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 EMR65138.1 - 2.5e-25 89.1 0.5 4e-25 88.5 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMR65138.1 - 1.7e-09 37.8 0.1 3e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EMR65138.1 - 0.00051 20.4 0.1 0.0023 18.3 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EMR65138.1 - 0.015 15.3 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PH_10 PF15411.1 EMR65139.1 - 1.1e-44 151.3 0.3 2.1e-44 150.4 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EMR65139.1 - 3.1e-30 105.3 0.1 6.2e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 EMR65139.1 - 7e-24 83.7 0.0 5.7e-23 80.7 0.0 2.3 2 0 0 2 2 2 1 CDC24 Calponin PB1 PF00564.19 EMR65139.1 - 1.5e-09 37.4 0.0 3.5e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 PB1 domain DNA_pol_phi PF04931.8 EMR65140.1 - 0.15 9.7 0.0 0.22 9.2 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pkinase_Tyr PF07714.12 EMR65140.1 - 0.18 10.8 0.0 4.9 6.1 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase EHN PF06441.7 EMR65142.1 - 2.4e-32 111.1 0.3 3.6e-32 110.5 0.2 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EMR65142.1 - 3e-08 33.8 0.1 5.2e-08 33.0 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR65142.1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_3 PF00933.16 EMR65144.1 - 4.4e-50 170.3 0.1 6.2e-50 169.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR65144.1 - 7.3e-47 159.7 0.0 1.6e-46 158.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR65144.1 - 6.8e-21 73.9 0.1 1.3e-20 73.1 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Epimerase PF01370.16 EMR65145.1 - 7.1e-20 71.4 0.0 2.3e-19 69.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR65145.1 - 3.6e-18 65.2 0.0 1.2e-17 63.5 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMR65145.1 - 4.2e-16 59.4 0.1 9.3e-16 58.3 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMR65145.1 - 2e-13 49.8 0.0 9.6e-07 27.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 EMR65145.1 - 8.1e-09 35.0 0.0 1.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EMR65145.1 - 2.6e-07 29.8 0.0 3.6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EMR65145.1 - 2.2e-06 27.6 0.3 5.1e-06 26.5 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR65145.1 - 0.00039 20.1 0.6 0.013 15.1 0.4 2.3 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EMR65145.1 - 0.015 14.2 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.15 EMR65145.1 - 0.05 13.5 0.1 0.79 9.6 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.10 EMR65145.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GST_C PF00043.20 EMR65146.1 - 1.4e-11 44.2 0.0 2.3e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMR65146.1 - 2e-09 37.1 0.1 4.9e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMR65146.1 - 1.5e-07 31.4 0.1 5e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMR65146.1 - 4.5e-07 29.9 0.0 8.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMR65146.1 - 1.7e-05 25.1 0.0 2.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMR65146.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DIOX_N PF14226.1 EMR65147.1 - 6.8e-14 52.3 0.0 7.2e-13 49.0 0.0 2.4 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMR65147.1 - 3.5e-08 33.6 0.0 6.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DHDPS PF00701.17 EMR65148.1 - 8.8e-49 165.6 0.0 9.9e-49 165.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 EMR65148.1 - 0.00036 19.8 0.0 0.00053 19.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase RNase_H PF00075.19 EMR65149.1 - 3.3e-17 63.0 0.0 5e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EMR65149.1 - 5.1e-05 22.9 0.0 0.0025 17.5 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase-like UPF0242 PF06785.6 EMR65149.1 - 0.044 12.4 0.2 0.062 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Nucleoplasmin PF03066.10 EMR65149.1 - 0.29 10.6 1.7 0.46 9.9 1.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EMR65149.1 - 1.2 9.4 5.9 2.3 8.5 4.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MFS_1 PF07690.11 EMR65150.1 - 5.5e-19 68.0 27.1 1.3e-16 60.3 16.5 3.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Med18 PF09637.5 EMR65151.1 - 9e-30 104.0 0.0 1e-29 103.8 0.0 1.0 1 0 0 1 1 1 1 Med18 protein Sugar_tr PF00083.19 EMR65152.1 - 4.4e-33 114.5 21.7 5.9e-29 100.9 5.5 3.0 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR65152.1 - 2e-08 33.3 24.8 7.4e-06 24.9 4.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily XPC-binding PF09280.6 EMR65152.1 - 0.033 13.6 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 XPC-binding domain WPP PF13943.1 EMR65152.1 - 0.068 13.3 0.1 20 5.4 0.0 2.4 2 0 0 2 2 2 0 WPP domain DUF3767 PF12597.3 EMR65152.1 - 0.083 12.5 1.3 0.24 11.0 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) p450 PF00067.17 EMR65153.1 - 1.8e-43 148.7 0.0 2.3e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Snf7 PF03357.16 EMR65154.1 - 1.1e-34 119.2 7.4 1.2e-34 119.1 5.1 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 EMR65154.1 - 0.0029 17.0 9.8 0.0034 16.8 5.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) Sec34 PF04136.10 EMR65154.1 - 0.062 12.9 2.9 0.52 9.9 1.5 2.1 2 0 0 2 2 2 0 Sec34-like family Methyltransf_6 PF03737.10 EMR65154.1 - 0.12 12.2 0.1 0.36 10.6 0.1 1.7 2 0 0 2 2 2 0 Demethylmenaquinone methyltransferase DUF342 PF03961.8 EMR65154.1 - 0.12 10.7 4.4 0.16 10.3 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF848 PF05852.6 EMR65154.1 - 0.14 11.9 6.8 0.039 13.7 2.6 1.7 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) BLOC1_2 PF10046.4 EMR65154.1 - 0.17 12.0 6.2 0.13 12.4 1.8 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4208 PF13907.1 EMR65154.1 - 0.18 12.0 2.3 0.33 11.1 1.1 1.9 1 1 1 2 2 1 0 Domain of unknown function (DUF4208) AAA_13 PF13166.1 EMR65154.1 - 0.19 10.1 5.8 0.41 9.0 4.1 1.4 1 1 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.15 EMR65154.1 - 0.21 11.3 13.9 1.3 8.8 0.0 3.6 2 1 0 2 2 2 0 Prefoldin subunit Phage_GP20 PF06810.6 EMR65154.1 - 0.21 11.0 6.0 0.19 11.1 2.9 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 H-kinase_dim PF02895.9 EMR65154.1 - 0.29 11.4 6.4 5.8 7.3 3.8 2.9 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DUF3584 PF12128.3 EMR65154.1 - 0.3 8.3 10.8 0.36 8.1 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.7 EMR65154.1 - 0.41 10.9 3.7 0.53 10.5 1.2 2.3 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein DNA_topoisoIV PF00521.15 EMR65154.1 - 1.1 7.9 5.5 1.4 7.6 3.8 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF2312 PF10073.4 EMR65154.1 - 1.4 8.3 6.0 1.5 8.2 0.5 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF724 PF05266.9 EMR65154.1 - 1.9 8.0 10.8 2 8.0 6.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 EMR65154.1 - 3 5.5 7.4 4.3 5.0 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 EMR65154.1 - 3.3 7.4 9.8 0.7 9.6 4.6 1.5 2 0 0 2 2 2 0 Laminin Domain II NYD-SP28_assoc PF14775.1 EMR65154.1 - 7 6.4 7.2 39 4.0 0.2 2.7 1 1 1 2 2 2 0 Sperm tail C-terminal domain Mnd1 PF03962.10 EMR65154.1 - 9.6 5.8 14.3 54 3.3 9.9 1.9 1 1 0 1 1 1 0 Mnd1 family Hydantoinase_B PF02538.9 EMR65155.1 - 1.4e-166 554.8 0.1 2.1e-85 286.9 0.0 2.1 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EMR65155.1 - 1.3e-94 316.5 0.0 3.1e-94 315.3 0.0 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EMR65155.1 - 1.4e-44 151.6 0.7 1.7e-42 144.9 0.0 2.9 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 EMR65155.1 - 0.034 13.4 0.2 0.077 12.3 0.2 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Aminotran_1_2 PF00155.16 EMR65156.1 - 6.6e-56 189.8 0.0 1.7e-49 168.7 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II GST_N PF02798.15 EMR65158.1 - 4.1e-08 33.2 0.2 1e-07 32.0 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR65158.1 - 4.4e-08 33.0 0.0 7.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMR65158.1 - 2.3e-07 30.9 0.0 4.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR65158.1 - 6.1e-07 29.2 0.0 2.4e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMR65158.1 - 0.00021 21.2 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMR65158.1 - 0.0022 18.4 0.0 0.0039 17.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WD40 PF00400.27 EMR65159.1 - 5.8e-39 130.6 7.3 2.6e-07 30.2 0.0 7.3 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 EMR65159.1 - 7.5e-13 47.9 0.2 2.3e-12 46.4 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMR65159.1 - 1.9e-07 30.5 0.0 5.7e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 F-box domain DUF605 PF04652.11 EMR65159.1 - 0.00058 19.3 20.0 0.00092 18.7 13.9 1.3 1 0 0 1 1 1 1 Vta1 like BBS2_Mid PF14783.1 EMR65159.1 - 0.015 15.0 0.1 9.5 6.0 0.0 3.8 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PAT1 PF09770.4 EMR65159.1 - 1.7 6.8 30.9 2.7 6.1 21.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glu-tRNAGln PF02686.10 EMR65163.1 - 0.0051 16.5 0.0 0.011 15.5 0.0 1.5 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit Creb_binding PF09030.5 EMR65163.1 - 0.017 15.2 3.4 0.031 14.4 2.4 1.4 1 0 0 1 1 1 0 Creb binding V-SNARE PF05008.10 EMR65164.1 - 1.3e-22 79.6 2.5 1.3e-22 79.6 1.8 2.2 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EMR65164.1 - 2.6e-17 62.6 4.0 2.6e-17 62.6 2.8 2.3 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EMR65164.1 - 9.3e-06 25.2 1.8 1.3e-05 24.7 0.2 2.1 2 1 0 2 2 2 1 Sec20 Fusion_gly PF00523.13 EMR65164.1 - 0.00022 19.4 1.5 0.005 14.9 0.3 2.2 2 0 0 2 2 2 1 Fusion glycoprotein F0 Laminin_I PF06008.9 EMR65164.1 - 0.0069 15.7 0.4 0.0069 15.7 0.3 2.2 2 0 0 2 2 2 1 Laminin Domain I Prominin PF05478.6 EMR65164.1 - 0.045 11.2 0.4 0.13 9.8 0.0 1.7 2 0 0 2 2 2 0 Prominin YqjK PF13997.1 EMR65164.1 - 0.077 13.1 1.1 3 8.0 0.1 2.8 3 0 0 3 3 3 0 YqjK-like protein CTNNBL PF08216.6 EMR65164.1 - 0.14 11.7 0.4 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear YvbH_ext PF11724.3 EMR65164.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 YvbH-like oligomerisation region Synaptobrevin PF00957.16 EMR65164.1 - 0.29 10.7 4.8 0.64 9.6 3.0 1.9 1 1 1 2 2 2 0 Synaptobrevin NUC173 PF08161.7 EMR65165.1 - 3.6e-80 267.9 0.0 4.1e-76 254.7 0.0 3.7 3 0 0 3 3 3 2 NUC173 domain TFCD_C PF12612.3 EMR65165.1 - 0.0091 15.4 1.4 1.2 8.5 0.0 3.9 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 EMR65165.1 - 0.039 14.2 7.7 1.2 9.5 0.5 4.6 4 0 0 4 4 4 0 HEAT repeats Glypican PF01153.14 EMR65165.1 - 0.046 12.3 0.4 0.086 11.4 0.3 1.4 1 0 0 1 1 1 0 Glypican HEAT PF02985.17 EMR65165.1 - 0.048 13.7 0.5 15 5.9 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat Vac14_Fab1_bd PF12755.2 EMR65165.1 - 0.08 13.3 0.1 10 6.5 0.0 3.7 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Nucleo_P87 PF07267.6 EMR65165.1 - 0.32 9.6 2.7 0.13 10.9 0.1 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 BUD22 PF09073.5 EMR65165.1 - 0.44 9.5 28.7 0.04 12.9 14.6 2.5 2 1 0 2 2 2 0 BUD22 FLO_LFY PF01698.11 EMR65165.1 - 2.7 6.7 4.5 5.6 5.6 3.1 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein SNAP PF14938.1 EMR65166.1 - 2.4e-117 391.1 7.7 2.7e-117 390.9 5.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EMR65166.1 - 5.6e-07 29.4 10.1 0.0011 18.8 0.9 3.3 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMR65166.1 - 1.8e-05 24.2 14.4 0.22 11.5 0.8 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMR65166.1 - 6.1e-05 23.5 10.2 0.043 14.4 0.0 4.0 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMR65166.1 - 0.00011 21.7 14.5 0.037 13.6 0.3 3.8 1 1 3 4 4 4 3 TPR repeat TPR_6 PF13174.1 EMR65166.1 - 0.0007 19.8 9.9 27 5.5 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMR65166.1 - 0.0052 16.4 10.1 1.6 8.6 0.0 5.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMR65166.1 - 0.34 10.7 11.1 22 5.1 0.4 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMR65166.1 - 0.68 9.6 18.6 1.5 8.5 1.1 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat RasGEF PF00617.14 EMR65167.1 - 7.4e-45 152.9 0.3 1.2e-44 152.3 0.2 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMR65167.1 - 3.8e-12 46.2 0.0 1e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.17 EMR65167.1 - 9e-06 25.1 0.0 2.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR65167.1 - 1.7e-05 25.2 0.0 0.0001 22.7 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein DUF726 PF05277.7 EMR65168.1 - 3.4e-101 338.5 0.1 4.9e-101 338.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 EMR65168.1 - 0.01 15.6 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR65168.1 - 0.038 13.5 0.0 0.089 12.3 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold CPSF100_C PF13299.1 EMR65168.1 - 0.15 12.2 1.6 0.41 10.8 1.1 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FAD_binding_4 PF01565.18 EMR65170.1 - 4.7e-22 77.9 0.3 8.8e-22 77.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR65170.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like Acetyltransf_8 PF13523.1 EMR65171.1 - 5.6e-27 94.4 0.2 8.8e-27 93.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NmrA PF05368.8 EMR65172.1 - 1.3e-18 67.0 0.0 2.1e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR65172.1 - 7.8e-12 45.5 0.2 6.6e-08 32.7 0.0 2.7 2 1 0 2 2 2 2 NADH(P)-binding Mito_carr PF00153.22 EMR65173.1 - 3.3e-42 142.0 9.7 8.9e-17 60.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pyr_redox_3 PF13738.1 EMR65176.1 - 1.2e-19 71.1 0.0 2.3e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR65176.1 - 2.2e-11 42.6 0.0 3.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMR65176.1 - 6.1e-10 38.5 0.0 1.8e-09 37.0 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMR65176.1 - 3.1e-08 33.7 0.0 3.7e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR65176.1 - 3e-05 23.9 0.1 0.00019 21.3 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR65176.1 - 0.0021 17.0 0.1 0.96 8.2 0.0 2.6 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EMR65176.1 - 0.0043 16.1 0.0 0.0093 15.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EMR65176.1 - 0.019 13.8 0.0 0.049 12.5 0.0 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EMR65176.1 - 0.064 12.0 0.1 8.6 5.0 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 EMR65176.1 - 0.097 12.4 0.0 2.4 7.9 0.0 2.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding MFS_1 PF07690.11 EMR65177.1 - 1.3e-23 83.2 37.7 1.3e-23 83.2 26.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR65177.1 - 7.2e-14 51.2 29.5 1.1e-13 50.6 20.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.13 EMR65177.1 - 0.24 11.0 0.7 0.52 9.9 0.5 1.4 1 0 0 1 1 1 0 Ribose/Galactose Isomerase Fungal_trans_2 PF11951.3 EMR65178.1 - 1.3e-05 24.0 0.2 1.9e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR65179.1 - 4.2e-07 29.7 7.2 7.5e-07 28.9 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMR65179.1 - 7.5e-07 28.2 0.2 1.5e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_18 PF00704.23 EMR65180.1 - 1.2e-91 307.6 0.1 1.4e-91 307.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DEAD PF00270.24 EMR65181.1 - 1.7e-41 141.5 0.0 2.5e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR65181.1 - 2e-23 82.0 0.1 4e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAT1 PF09770.4 EMR65181.1 - 9.9 4.2 16.1 14 3.7 11.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 adh_short PF00106.20 EMR65182.1 - 1.3e-15 57.7 0.2 8.7e-15 55.0 0.0 2.2 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 EMR65182.1 - 4e-06 26.6 0.0 9.5e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EMR65182.1 - 0.0094 15.4 0.0 0.025 14.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMR65182.1 - 0.028 14.1 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EMR65182.1 - 0.035 13.3 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family GIT1_C PF12205.3 EMR65182.1 - 0.16 11.8 0.0 0.41 10.4 0.0 1.6 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term GatB_N PF02934.10 EMR65183.1 - 1e-98 329.7 0.0 1.3e-98 329.4 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EMR65183.1 - 2.7e-10 40.1 0.0 4.6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 GatB domain Glyco_hydro_31 PF01055.21 EMR65184.1 - 4.1e-81 273.0 3.7 5.7e-81 272.5 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Lipase_GDSL_2 PF13472.1 EMR65186.1 - 3.7e-15 56.5 1.1 4.5e-15 56.2 0.8 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMR65186.1 - 1.9e-09 37.7 0.3 2.4e-09 37.3 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cytomega_UL20A PF05984.7 EMR65186.1 - 0.036 14.2 1.2 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein KR PF08659.5 EMR65187.1 - 5.9e-53 179.2 0.1 5.9e-52 175.9 0.1 2.7 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EMR65187.1 - 3.9e-40 137.4 6.7 5.5e-40 137.0 0.1 3.9 5 0 0 5 5 5 1 short chain dehydrogenase PS-DH PF14765.1 EMR65187.1 - 1.1e-19 70.6 0.2 3.2e-19 69.1 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 EMR65187.1 - 1.6e-07 30.9 0.1 4.9e-07 29.3 0.1 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR65187.1 - 1.3e-06 28.1 0.0 6e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EMR65187.1 - 4.1e-05 23.7 0.0 8.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EMR65187.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMR65187.1 - 0.0044 15.9 0.5 0.012 14.5 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMR65187.1 - 0.059 12.0 0.1 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ThiF PF00899.16 EMR65187.1 - 0.061 13.1 1.1 0.2 11.4 0.8 1.9 1 1 0 1 1 1 0 ThiF family DUF619 PF04768.8 EMR65188.1 - 3.9e-47 159.8 0.5 6.9e-47 159.0 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EMR65188.1 - 3.6e-31 107.9 0.0 1.6e-30 105.9 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EMR65188.1 - 6.1e-25 88.1 0.0 1.3e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family GFO_IDH_MocA PF01408.17 EMR65188.1 - 0.0007 20.0 0.0 0.0021 18.5 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EMR65188.1 - 0.01 15.7 0.0 0.039 13.8 0.0 2.1 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Asp PF00026.18 EMR65190.1 - 2.4e-69 234.0 2.6 3e-69 233.6 1.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMR65190.1 - 9e-09 35.4 0.0 1.1e-07 31.9 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMR65190.1 - 0.00053 20.4 0.6 1.9 9.0 0.0 3.5 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.1 EMR65190.1 - 0.0015 18.3 0.4 0.18 11.6 0.1 2.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Sulfatase PF00884.18 EMR65190.1 - 0.012 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Sulfatase CTDII PF01556.13 EMR65191.1 - 9.3e-19 67.1 0.0 2.7e-17 62.4 0.0 2.8 3 0 0 3 3 3 1 DnaJ C terminal domain Cob_adeno_trans PF01923.13 EMR65191.1 - 0.0027 17.5 1.2 0.024 14.4 0.1 2.3 1 1 1 2 2 2 1 Cobalamin adenosyltransferase DUF2408 PF10303.4 EMR65191.1 - 0.053 13.6 2.3 0.19 11.8 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Syntaxin-6_N PF09177.6 EMR65191.1 - 0.067 13.6 1.8 12 6.3 0.1 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Amidohydro_5 PF13594.1 EMR65192.1 - 2.7e-14 52.7 2.0 3.4e-14 52.3 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EMR65192.1 - 3.3e-14 53.2 0.0 7.8e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMR65192.1 - 2.9e-05 24.2 3.3 0.0097 15.9 0.1 2.8 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EMR65192.1 - 0.0012 18.0 5.1 0.049 12.8 1.3 2.4 1 1 0 1 1 1 1 Amidohydrolase family Hemerythrin PF01814.18 EMR65194.1 - 1.9e-12 47.5 0.5 2.4e-12 47.1 0.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Cyclase PF04199.8 EMR65195.1 - 4.2e-14 52.5 0.0 6.2e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase EzrA PF06160.7 EMR65196.1 - 1.7e-05 23.2 7.9 0.0039 15.4 0.6 2.1 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA Tropomyosin_1 PF12718.2 EMR65196.1 - 2.2e-05 24.3 0.8 2.2e-05 24.3 0.6 2.9 1 1 2 3 3 3 1 Tropomyosin like Sipho_Gp157 PF05565.6 EMR65196.1 - 0.0026 17.3 18.3 0.99 8.9 4.0 3.1 2 1 1 3 3 3 3 Siphovirus Gp157 DUF1664 PF07889.7 EMR65196.1 - 0.0053 16.5 13.5 0.01 15.6 0.9 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 EMR65196.1 - 0.0086 15.9 6.0 0.78 9.5 1.3 3.3 1 1 2 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 EMR65196.1 - 0.017 13.6 11.4 0.042 12.3 7.8 1.7 1 1 0 1 1 1 0 AAA domain SDH_alpha PF03313.10 EMR65196.1 - 0.023 13.7 1.4 2.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Serine dehydratase alpha chain Reo_sigmaC PF04582.7 EMR65196.1 - 0.031 13.4 5.1 0.056 12.6 3.3 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EMR65196.1 - 0.089 13.0 7.4 8.9 6.6 0.4 3.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 EMR65196.1 - 0.16 12.0 10.3 0.11 12.6 0.3 3.0 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Surfac_D-trimer PF09006.6 EMR65196.1 - 0.16 11.6 10.1 9.9 5.9 0.1 5.0 6 1 0 6 6 6 0 Lung surfactant protein D coiled-coil trimerisation TPX2 PF06886.6 EMR65196.1 - 0.21 11.6 12.3 1.5 8.9 1.6 3.4 2 1 1 3 3 3 0 Targeting protein for Xklp2 (TPX2) Laminin_II PF06009.7 EMR65196.1 - 0.28 10.9 9.3 0.32 10.7 0.2 2.8 1 1 0 2 2 2 0 Laminin Domain II Bacillus_HBL PF05791.6 EMR65196.1 - 0.39 10.0 5.0 0.29 10.4 1.1 2.4 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF3086 PF11285.3 EMR65196.1 - 0.63 8.7 8.0 0.3 9.8 3.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) HR1 PF02185.11 EMR65196.1 - 0.71 9.6 14.4 7 6.4 2.0 4.1 3 2 0 3 3 3 0 Hr1 repeat Fmp27_WPPW PF10359.4 EMR65196.1 - 1.1 7.5 11.8 3 6.1 0.2 2.4 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain KfrA_N PF11740.3 EMR65196.1 - 1.2 9.6 18.0 0.14 12.6 5.9 3.0 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term BLOC1_2 PF10046.4 EMR65196.1 - 1.4 9.1 12.8 1.9 8.6 0.5 4.0 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF342 PF03961.8 EMR65196.1 - 2.6 6.3 14.9 0.31 9.4 4.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) COG2 PF06148.6 EMR65196.1 - 2.7 7.8 13.6 7.3 6.4 0.4 3.8 1 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Noelin-1 PF12308.3 EMR65196.1 - 2.8 7.8 7.6 2.3 8.0 0.1 3.2 2 1 3 5 5 5 0 Neurogenesis glycoprotein GP41 PF00517.12 EMR65196.1 - 3.5 7.1 7.3 4.7 6.7 0.2 3.4 4 0 0 4 4 4 0 Retroviral envelope protein Allexi_40kDa PF05549.6 EMR65196.1 - 4.1 6.6 10.7 12 5.0 0.9 3.1 1 1 2 3 3 3 0 Allexivirus 40kDa protein FlaC_arch PF05377.6 EMR65196.1 - 6.1 6.8 11.5 20 5.1 0.8 4.5 2 1 2 5 5 5 0 Flagella accessory protein C (FlaC) FUSC PF04632.7 EMR65196.1 - 9.5 4.5 9.6 4.6 5.5 4.7 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family 2OG-FeII_Oxy_3 PF13640.1 EMR65197.1 - 1.4e-09 38.3 0.0 2.3e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EMR65197.1 - 5e-06 26.0 0.1 9.9e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMR65197.1 - 0.016 15.4 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Tet_JBP PF12851.2 EMR65197.1 - 0.058 12.6 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily YL1 PF05764.8 EMR65198.1 - 2.9e-57 194.0 24.8 2.9e-57 194.0 17.2 2.7 3 0 0 3 3 3 1 YL1 nuclear protein MFS_1 PF07690.11 EMR65199.1 - 3.5e-08 32.5 9.4 3.5e-08 32.5 6.5 1.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR65199.1 - 0.00021 20.0 1.5 0.00025 19.7 1.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter CAP_N PF01213.14 EMR65199.1 - 0.43 9.8 4.8 0.6 9.3 3.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EMR65199.1 - 3.4 6.9 7.0 4.5 6.5 4.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator MFS_1 PF07690.11 EMR65200.1 - 1e-19 70.5 34.3 1.2e-14 53.8 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR65200.1 - 8.3e-10 37.8 17.0 1.2e-09 37.2 11.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Colicin_C PF12106.3 EMR65200.1 - 0.1 12.2 0.3 0.1 12.2 0.2 2.0 2 0 0 2 2 2 0 Colicin C terminal ribonuclease domain Ferric_reduct PF01794.14 EMR65201.1 - 2.3e-12 47.1 6.6 3.8e-12 46.3 4.6 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EMR65201.1 - 3.5e-11 42.8 0.0 5.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMR65201.1 - 0.00096 19.0 0.0 0.0029 17.5 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Gln-synt_C PF00120.19 EMR65202.1 - 2.9e-39 134.7 0.0 4.6e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Aldedh PF00171.17 EMR65203.1 - 2.9e-133 444.5 0.1 3.4e-133 444.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DnaJ-X PF14308.1 EMR65204.1 - 3.2e-69 232.3 3.8 3.2e-69 232.3 2.7 2.2 2 1 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EMR65204.1 - 3.3e-25 87.5 1.4 8e-25 86.3 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain Activator-TraM PF11657.3 EMR65204.1 - 0.93 8.9 6.7 0.11 12.0 1.3 1.9 2 0 0 2 2 2 0 Transcriptional activator TraM Synaphin PF05835.7 EMR65205.1 - 0.028 14.5 6.2 0.073 13.2 4.3 1.6 1 0 0 1 1 1 0 Synaphin protein DUF3496 PF12001.3 EMR65205.1 - 0.044 14.0 3.8 0.2 11.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) PGA_cap PF09587.5 EMR65205.1 - 0.063 12.6 0.3 0.084 12.2 0.2 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap KdpC PF02669.10 EMR65205.1 - 0.066 12.8 0.5 0.099 12.3 0.4 1.2 1 0 0 1 1 1 0 K+-transporting ATPase, c chain DUF4613 PF15390.1 EMR65205.1 - 0.16 10.1 6.5 0.18 9.9 4.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Utp11 PF03998.8 EMR65205.1 - 0.27 11.0 12.0 0.45 10.3 8.3 1.4 1 0 0 1 1 1 0 Utp11 protein V_ATPase_I PF01496.14 EMR65205.1 - 4.3 5.0 8.6 5.3 4.7 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADH_N PF08240.7 EMR65206.1 - 6.4e-25 87.0 1.2 1.3e-24 86.0 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EMR65206.1 - 4.2e-09 35.8 2.3 2.4e-08 33.4 0.1 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 EMR65206.1 - 5e-08 32.5 0.2 0.00027 20.4 0.0 2.7 3 0 0 3 3 3 2 Zinc-binding dehydrogenase Fungal_trans PF04082.13 EMR65207.1 - 1.7e-11 43.4 0.4 1.7e-11 43.4 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain BAF1_ABF1 PF04684.8 EMR65207.1 - 0.02 13.7 11.9 0.029 13.2 8.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FCP1_C PF09309.5 EMR65207.1 - 0.98 8.6 5.5 1.6 7.9 3.4 1.5 2 0 0 2 2 2 0 FCP1, C-terminal DUF1996 PF09362.5 EMR65208.1 - 1.4e-63 214.7 0.0 2.1e-63 214.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EMR65208.1 - 6.6e-16 58.0 4.9 1.3e-15 57.0 3.4 1.5 1 0 0 1 1 1 1 WSC domain Hydrolase_6 PF13344.1 EMR65210.1 - 3.2e-23 81.5 0.0 6.4e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR65210.1 - 8.5e-13 47.8 0.0 1.7e-11 43.6 0.0 2.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EMR65210.1 - 0.002 18.6 0.0 0.0088 16.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMR65210.1 - 0.0026 18.0 0.0 3 8.0 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase FSH1 PF03959.8 EMR65211.1 - 2.1e-28 99.2 0.0 4.9e-27 94.7 0.0 2.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EMR65211.1 - 9e-06 25.7 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EMR65211.1 - 0.13 10.9 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Carboxylesterase family AAA PF00004.24 EMR65212.1 - 9.9e-35 119.6 0.0 7.3e-34 116.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR65212.1 - 5.9e-06 26.4 0.1 0.0024 17.9 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EMR65212.1 - 6.6e-05 22.9 0.0 0.0079 16.2 0.0 3.2 2 2 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EMR65212.1 - 8.4e-05 23.3 0.1 0.00099 19.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMR65212.1 - 8.7e-05 22.2 0.0 0.00029 20.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EMR65212.1 - 0.0001 22.1 0.0 0.00039 20.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EMR65212.1 - 0.0001 21.7 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EMR65212.1 - 0.00018 20.6 0.0 0.00039 19.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EMR65212.1 - 0.0016 18.3 0.0 0.0055 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EMR65212.1 - 0.0022 16.7 0.2 0.013 14.2 0.1 2.1 2 1 1 3 3 3 1 TIP49 C-terminus Arch_ATPase PF01637.13 EMR65212.1 - 0.004 16.9 0.0 1.7 8.2 0.0 3.0 3 1 0 3 3 2 1 Archaeal ATPase Sigma54_activ_2 PF14532.1 EMR65212.1 - 0.0051 16.8 0.0 0.029 14.4 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 EMR65212.1 - 0.0055 16.4 0.2 0.018 14.7 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 EMR65212.1 - 0.0065 15.9 0.1 0.029 13.8 0.0 2.2 2 1 0 2 2 2 1 Sigma-54 interaction domain IPT PF01745.11 EMR65212.1 - 0.0072 15.5 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Isopentenyl transferase AAA_18 PF13238.1 EMR65212.1 - 0.0098 16.1 0.0 0.059 13.6 0.0 2.4 3 0 0 3 3 1 1 AAA domain RNA_helicase PF00910.17 EMR65212.1 - 0.012 15.7 0.0 0.062 13.4 0.0 2.3 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EMR65212.1 - 0.024 14.0 0.1 0.21 10.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.1 EMR65212.1 - 0.027 14.0 0.1 0.13 11.7 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_2 PF07724.9 EMR65212.1 - 0.034 14.0 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EMR65212.1 - 0.039 13.0 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.12 EMR65212.1 - 0.04 12.8 0.0 0.079 11.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 EMR65212.1 - 0.046 13.6 0.1 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 EMR65212.1 - 0.047 13.3 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_24 PF13479.1 EMR65212.1 - 0.052 13.1 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EMR65212.1 - 0.059 12.7 0.0 3 7.2 0.0 2.6 1 1 1 2 2 2 0 AAA-like domain Mg_chelatase PF01078.16 EMR65212.1 - 0.1 11.7 0.1 0.37 9.9 0.0 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EMR65212.1 - 0.16 11.5 0.0 0.76 9.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SHMT PF00464.14 EMR65213.1 - 3.3e-158 526.2 0.0 4.1e-158 525.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase V-ATPase_G PF03179.10 EMR65214.1 - 1.3e-27 96.1 13.9 1.5e-27 95.9 9.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit FAM91_C PF14648.1 EMR65214.1 - 0.1 11.3 2.6 0.13 11.1 1.8 1.0 1 0 0 1 1 1 0 FAM91 C-terminus DUF2201_N PF13203.1 EMR65214.1 - 0.11 11.6 4.7 0.12 11.5 3.3 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Striatin PF08232.7 EMR65214.1 - 0.21 11.9 6.1 0.25 11.6 4.2 1.1 1 0 0 1 1 1 0 Striatin family OmpH PF03938.9 EMR65214.1 - 0.24 11.3 7.2 0.29 11.0 5.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2870 PF11069.3 EMR65214.1 - 0.37 10.8 5.0 0.49 10.4 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) RRF PF01765.14 EMR65214.1 - 0.52 9.7 9.7 0.64 9.4 6.7 1.2 1 0 0 1 1 1 0 Ribosome recycling factor U79_P34 PF03064.11 EMR65214.1 - 0.8 9.1 9.1 0.83 9.1 6.3 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SAPS PF04499.10 EMR65214.1 - 1.2 7.7 7.1 1.2 7.6 4.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.5 EMR65214.1 - 1.6 8.7 10.4 1.8 8.5 7.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1912 PF08930.5 EMR65214.1 - 3.1 7.9 6.4 1.1 9.4 2.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1912) DUF4407 PF14362.1 EMR65214.1 - 3.6 6.4 7.2 3.7 6.4 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.1 EMR65214.1 - 4 7.2 8.3 5.2 6.8 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HA2 PF04408.18 EMR65215.1 - 4.1e-19 68.5 2.1 5.9e-19 67.9 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMR65215.1 - 1e-13 50.9 0.2 3.7e-13 49.1 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EMR65215.1 - 5.4e-07 29.4 0.0 1.7e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EMR65215.1 - 4.5e-05 23.0 0.1 0.0001 21.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase His_Phos_1 PF00300.17 EMR65216.1 - 1.8e-17 63.9 0.0 2.3e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4037 PF13228.1 EMR65216.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) FAD_binding_4 PF01565.18 EMR65217.1 - 1.8e-17 63.0 1.7 2.9e-17 62.4 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR65217.1 - 2.4e-08 33.7 0.0 7.4e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like Abhydrolase_4 PF08386.5 EMR65218.1 - 4.7e-17 61.7 0.0 1.2e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EMR65218.1 - 3.2e-13 49.7 0.0 1.3e-10 41.2 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Epimerase PF01370.16 EMR65218.1 - 3.4e-12 46.3 0.1 1.6e-11 44.0 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_6 PF12697.2 EMR65218.1 - 1.1e-10 41.8 0.1 4.3e-10 39.8 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family NAD_binding_10 PF13460.1 EMR65218.1 - 1.9e-10 41.0 0.3 4.7e-10 39.7 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMR65218.1 - 9.1e-08 31.1 0.0 5.5e-07 28.5 0.0 2.2 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EMR65218.1 - 5.3e-07 29.1 0.3 9e-07 28.3 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Abhydrolase_5 PF12695.2 EMR65218.1 - 2.8e-05 23.9 0.1 0.00061 19.5 0.0 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family TrkA_N PF02254.13 EMR65218.1 - 4e-05 23.6 0.3 8.8e-05 22.4 0.2 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.10 EMR65218.1 - 0.00076 19.3 0.1 0.0014 18.4 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 EMR65218.1 - 0.0037 16.2 0.3 0.0055 15.7 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 EMR65218.1 - 0.0042 16.0 0.0 0.18 10.6 0.1 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain ApbA PF02558.11 EMR65218.1 - 0.01 15.2 0.1 0.02 14.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EMR65218.1 - 0.016 14.3 0.0 0.042 13.0 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EMR65218.1 - 0.028 13.8 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 EMR65218.1 - 0.045 13.3 0.1 0.093 12.2 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EMR65218.1 - 0.053 13.1 0.3 0.09 12.4 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EMR65218.1 - 0.074 13.4 0.1 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4350 PF14258.1 EMR65218.1 - 0.16 12.1 0.8 35 4.7 0.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4350) Pox_D5 PF03288.11 EMR65219.1 - 0.012 15.8 0.1 0.014 15.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus D5 protein-like Glyco_hydro_2_N PF02837.13 EMR65220.1 - 7.3e-26 90.6 0.2 1.9e-25 89.3 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EMR65220.1 - 1.4e-11 43.8 0.2 2.2e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EMR65220.1 - 2.1e-10 41.0 0.1 2.1e-09 37.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 zf-MYND PF01753.13 EMR65221.1 - 2.1e-10 40.2 15.0 4.1e-10 39.3 10.4 1.5 1 0 0 1 1 1 1 MYND finger Cyt-b5 PF00173.23 EMR65222.1 - 1.1e-13 50.7 0.0 2e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RNA_pol_Rpb2_6 PF00562.23 EMR65223.1 - 5.9e-125 417.0 0.1 1.9e-124 415.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EMR65223.1 - 5.1e-57 192.0 0.0 8.2e-57 191.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EMR65223.1 - 1.9e-47 161.1 0.0 3.8e-47 160.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EMR65223.1 - 6e-30 103.3 0.0 1.4e-29 102.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EMR65223.1 - 7.2e-25 86.7 1.0 1.7e-24 85.5 0.7 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EMR65223.1 - 1.2e-22 79.4 0.1 3.4e-22 77.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 EMR65223.1 - 3.9e-21 74.6 0.1 1e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 KR PF08659.5 EMR65224.1 - 8e-61 204.8 1.1 8e-61 204.8 0.8 3.4 4 0 0 4 4 3 1 KR domain Acyl_transf_1 PF00698.16 EMR65224.1 - 1.1e-53 182.6 1.7 1.9e-53 181.8 1.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EMR65224.1 - 5.2e-51 173.5 0.0 9.4e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 EMR65224.1 - 1.1e-50 172.5 0.2 3.1e-49 167.7 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 EMR65224.1 - 1.1e-46 158.7 0.9 1.1e-46 158.7 0.6 2.8 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMR65224.1 - 4.2e-35 120.1 0.4 1.2e-34 118.7 0.3 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EMR65224.1 - 2.3e-20 72.4 0.0 1.2e-19 70.1 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMR65224.1 - 1.9e-17 63.5 0.0 8.1e-16 58.3 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 EMR65224.1 - 8.4e-11 41.6 0.1 2.2e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EMR65224.1 - 1.4e-10 41.5 0.0 1.6e-09 38.1 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR65224.1 - 1.5e-10 41.0 0.0 3.5e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR65224.1 - 4.5e-08 33.6 0.0 2.4e-07 31.3 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR65224.1 - 3.2e-06 26.7 0.0 1.1e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR65224.1 - 0.00022 21.5 0.0 0.0014 18.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EMR65224.1 - 0.0003 21.0 0.0 0.00089 19.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 EMR65224.1 - 0.0028 16.7 0.0 0.0072 15.4 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EMR65224.1 - 0.0061 16.5 0.0 0.056 13.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain DUF915 PF06028.6 EMR65224.1 - 0.033 13.2 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Phage_Coat_B PF05356.6 EMR65224.1 - 0.038 13.6 1.3 0.095 12.4 0.1 2.3 2 0 0 2 2 1 0 Phage Coat protein B adh_short PF00106.20 EMR65225.1 - 1.7e-24 86.6 0.6 2.2e-24 86.2 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR65225.1 - 6.9e-20 71.8 0.0 8.6e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR65225.1 - 2e-09 37.3 0.3 3.3e-09 36.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMR65225.1 - 0.038 13.7 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EMR65225.1 - 0.056 12.5 0.0 0.32 10.0 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF706 PF05153.10 EMR65226.1 - 6.9e-128 425.2 1.4 9.9e-128 424.7 1.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) AAA PF00004.24 EMR65226.1 - 9.3e-08 32.3 0.0 1.8e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MR_MLE_C PF13378.1 EMR65227.1 - 7.7e-20 70.9 0.0 2e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EMR65227.1 - 7.6e-12 45.5 0.0 2e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EMR65227.1 - 5.7e-10 39.2 0.0 9.2e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain HEAT PF02985.17 EMR65229.1 - 5.4e-37 122.5 43.8 0.0054 16.7 0.0 22.3 24 0 0 24 24 23 8 HEAT repeat HEAT_2 PF13646.1 EMR65229.1 - 1.1e-36 124.9 49.1 1.2e-09 38.2 0.1 16.6 8 3 8 16 16 16 10 HEAT repeats HEAT_EZ PF13513.1 EMR65229.1 - 3e-34 116.6 57.7 5.4e-06 26.7 0.0 22.6 15 4 8 24 24 23 12 HEAT-like repeat DUF3554 PF12074.3 EMR65229.1 - 3e-28 99.2 3.1 8.8e-16 58.2 0.1 4.7 3 1 1 4 4 4 2 Domain of unknown function (DUF3554) Vac14_Fab1_bd PF12755.2 EMR65229.1 - 1.5e-16 60.5 0.0 0.48 10.8 0.0 9.7 7 2 3 10 10 10 4 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EMR65229.1 - 1.4e-13 50.7 0.0 0.0072 15.7 0.0 6.8 5 1 2 7 7 7 4 CLASP N terminal Cnd1 PF12717.2 EMR65229.1 - 8.3e-12 45.3 0.1 0.85 9.4 0.0 8.5 7 2 2 9 9 9 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EMR65229.1 - 8.9e-12 45.2 2.0 0.00084 19.2 0.0 5.5 6 0 0 6 6 6 3 Parkin co-regulated protein MMS19_C PF12460.3 EMR65229.1 - 2e-06 26.8 12.0 0.25 10.0 0.1 7.5 7 0 0 7 7 7 3 RNAPII transcription regulator C-terminal Ipi1_N PF12333.3 EMR65229.1 - 3.4e-05 23.7 0.1 0.015 15.2 0.0 5.4 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation DUF4563 PF15124.1 EMR65229.1 - 0.082 12.4 0.0 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4563) DUF3896 PF13035.1 EMR65229.1 - 4.2 7.5 4.6 15 5.7 3.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) RRM_1 PF00076.17 EMR65230.1 - 1.5e-41 139.8 0.1 2.7e-12 46.1 0.1 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR65230.1 - 5.7e-38 128.7 0.0 1.6e-10 40.8 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR65230.1 - 3.1e-19 68.5 0.0 8.8e-07 28.6 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMR65230.1 - 1.2e-05 25.0 0.0 0.12 12.1 0.0 3.7 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 EMR65230.1 - 9.2e-05 21.7 0.1 0.00024 20.4 0.1 1.7 1 0 0 1 1 1 1 Lsm interaction motif Nup35_RRM PF05172.8 EMR65230.1 - 0.014 15.1 0.1 0.12 12.1 0.0 2.5 3 1 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF3306 PF11748.3 EMR65230.1 - 0.21 12.2 6.9 0.18 12.4 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Ribosomal_L19e PF01280.15 EMR65231.1 - 1.6e-60 203.1 7.9 1.6e-60 203.1 5.5 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 EMR65231.1 - 0.018 14.2 0.9 0.018 14.2 0.6 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF3043 PF11241.3 EMR65231.1 - 5.2 6.6 13.8 11 5.5 9.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) CTNNBL PF08216.6 EMR65232.1 - 6.9e-31 106.0 0.3 2e-29 101.3 0.0 2.7 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear IMS_C PF11799.3 EMR65232.1 - 0.039 13.8 0.1 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 impB/mucB/samB family C-terminal domain Glyco_transf_22 PF03901.12 EMR65234.1 - 1.6e-26 93.2 8.2 2e-26 92.9 5.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Phospholip_A2_3 PF09056.6 EMR65235.1 - 0.065 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic phospholipase A2 Mito_carr PF00153.22 EMR65236.1 - 3e-51 171.1 6.4 3.3e-19 68.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF998 PF06197.8 EMR65236.1 - 0.02 14.2 0.1 0.32 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF998) DUF218 PF02698.12 EMR65237.1 - 7.9e-32 109.8 0.0 1.1e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain AA_permease_2 PF13520.1 EMR65238.1 - 3.2e-24 85.2 12.4 3.2e-24 85.2 8.6 2.8 2 1 1 3 3 3 2 Amino acid permease AA_permease PF00324.16 EMR65238.1 - 1.4e-10 40.1 28.1 2.9e-09 35.7 10.1 2.3 2 1 0 2 2 2 2 Amino acid permease Ubie_methyltran PF01209.13 EMR65240.1 - 1.5e-13 50.4 0.0 3.3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EMR65240.1 - 9.9e-11 41.9 0.0 1.9e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR65240.1 - 2.7e-10 40.0 0.0 7.7e-10 38.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR65240.1 - 5.5e-08 32.6 0.0 1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR65240.1 - 6.4e-08 32.9 0.1 5.8e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR65240.1 - 3.7e-07 30.4 0.0 7.5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR65240.1 - 0.00018 21.5 0.0 0.00036 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMR65240.1 - 0.1 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.6 EMR65240.1 - 0.17 10.8 0.1 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) RRM_1 PF00076.17 EMR65241.1 - 9.7e-09 34.7 0.0 1.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR65241.1 - 3.2e-08 33.3 0.0 5.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR65241.1 - 1.8e-05 24.6 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMR65241.1 - 0.0003 20.4 0.0 0.00062 19.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EMR65241.1 - 0.071 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif F-box-like PF12937.2 EMR65243.1 - 0.00012 21.7 0.0 0.00085 18.9 0.0 2.4 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EMR65243.1 - 0.0071 16.0 0.0 0.022 14.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like domain Xylo_C PF12529.3 EMR65243.1 - 0.021 14.2 0.1 1.1 8.6 0.1 2.2 2 0 0 2 2 2 0 Xylosyltransferase C terminal DnaJ PF00226.26 EMR65246.1 - 4e-20 71.3 0.7 4e-20 71.3 0.5 2.7 2 1 0 2 2 2 1 DnaJ domain Ald_Xan_dh_C2 PF02738.13 EMR65246.1 - 0.016 13.5 5.5 0.69 8.1 2.6 2.2 2 0 0 2 2 2 0 Molybdopterin-binding domain of aldehyde dehydrogenase Peptidase_M14 PF00246.19 EMR65247.1 - 2.3e-64 217.7 0.0 2.6e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Complex1_LYR PF05347.10 EMR65248.1 - 1.8e-07 30.8 0.0 2.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMR65248.1 - 2.5e-06 27.5 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF924 PF06041.6 EMR65248.1 - 0.073 12.8 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) Complex1_LYR_2 PF13233.1 EMR65248.1 - 0.11 12.9 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like PA14_2 PF10528.4 EMR65249.1 - 1.3e-22 79.9 3.1 1.3e-22 79.9 2.1 2.6 3 0 0 3 3 3 1 GLEYA domain DUF4394 PF14339.1 EMR65250.1 - 0.00084 18.7 1.4 1.7 7.8 0.1 3.3 2 1 2 4 4 4 4 Domain of unknown function (DUF4394) SdiA-regulated PF06977.6 EMR65250.1 - 0.12 11.2 0.0 0.25 10.2 0.0 1.4 2 0 0 2 2 2 0 SdiA-regulated MCM PF00493.18 EMR65251.1 - 3.4e-139 463.2 0.3 4.7e-139 462.8 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EMR65251.1 - 2e-31 109.0 39.8 2e-31 109.0 27.6 2.7 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EMR65251.1 - 3.1e-21 76.0 0.4 8.5e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMR65251.1 - 2.4e-07 30.1 0.0 6.6e-06 25.4 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMR65251.1 - 1.1e-05 25.1 0.0 2.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EMR65251.1 - 0.0024 17.3 0.2 0.01 15.3 0.2 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EMR65251.1 - 0.0043 16.6 0.1 0.053 13.1 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MFS_1 PF07690.11 EMR65252.1 - 9.1e-15 54.2 22.4 9.1e-15 54.2 15.5 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily 4HBT PF03061.17 EMR65253.1 - 4.3e-08 33.1 1.0 6.4e-08 32.6 0.5 1.4 1 1 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EMR65253.1 - 9.8e-05 22.2 0.6 0.00013 21.8 0.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT_2 PF13279.1 EMR65253.1 - 0.02 15.3 0.0 0.02 15.3 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily MaoC_dehydratas PF01575.14 EMR65253.1 - 0.053 12.9 0.1 0.079 12.3 0.1 1.2 1 0 0 1 1 1 0 MaoC like domain IDO PF01231.13 EMR65254.1 - 1.6e-159 530.9 0.0 1.8e-159 530.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Peptidase_S8 PF00082.17 EMR65255.1 - 6.2e-40 137.1 12.7 9.2e-40 136.5 8.8 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMR65255.1 - 1.3e-13 51.3 0.0 2.7e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 adh_short PF00106.20 EMR65256.1 - 3.8e-31 108.2 0.7 5.5e-31 107.7 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR65256.1 - 3.4e-26 92.4 0.0 4e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR65256.1 - 2.8e-15 56.4 0.6 4.4e-15 55.8 0.4 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMR65256.1 - 0.021 13.7 0.1 0.025 13.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EMR65256.1 - 0.043 13.4 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EPO_TPO PF00758.13 EMR65256.1 - 0.051 13.2 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin DLH PF01738.13 EMR65257.1 - 1.6e-17 63.5 0.0 3.6e-17 62.3 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMR65257.1 - 0.00013 21.7 0.0 0.00024 20.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Rep_N PF08724.5 EMR65259.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Rep protein catalytic domain like SPDY PF03771.11 EMR65259.1 - 0.039 13.4 0.4 0.085 12.3 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF317) DUF3716 PF12511.3 EMR65260.1 - 2.4e-14 52.6 2.3 3.9e-14 52.0 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Zn_clus PF00172.13 EMR65260.1 - 5.1 7.1 7.8 16 5.4 1.2 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Arylsulfotran_2 PF14269.1 EMR65261.1 - 3.2e-54 184.1 1.4 4.9e-54 183.5 0.5 1.6 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EMR65261.1 - 1.8e-22 79.5 1.0 3.6e-22 78.5 0.7 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) zf-UBR PF02207.15 EMR65262.1 - 6.1e-16 57.9 8.2 6.1e-16 57.9 5.7 3.3 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Nop14 PF04147.7 EMR65262.1 - 1.1 7.0 6.5 1.8 6.3 4.5 1.2 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.11 EMR65263.1 - 4.2e-18 65.1 28.6 9.6e-12 44.2 14.2 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR65263.1 - 0.019 13.5 21.0 0.086 11.3 2.4 2.7 2 1 0 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.11 EMR65264.1 - 1.9e-28 99.1 40.6 2.5e-28 98.7 28.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 EMR65264.1 - 0.0099 15.8 0.4 0.0099 15.8 0.3 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) Vps23_core PF09454.5 EMR65265.1 - 8e-20 70.2 0.0 1.4e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain mTERF PF02536.9 EMR65265.1 - 0.15 10.6 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 mTERF Sugar_tr PF00083.19 EMR65266.1 - 5.4e-93 312.0 11.0 6.3e-93 311.7 7.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR65266.1 - 1.8e-34 119.0 36.9 8e-27 93.8 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EMR65266.1 - 0.00014 21.8 5.7 0.056 13.4 0.4 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) OATP PF03137.15 EMR65266.1 - 0.0006 17.9 5.9 0.011 13.8 0.6 2.1 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 EMR65266.1 - 0.0018 16.7 2.6 0.0018 16.7 1.8 3.3 2 2 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EMR65266.1 - 0.054 11.6 8.9 0.0083 14.3 1.1 2.5 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Hce2 PF14856.1 EMR65267.1 - 3.3e-07 30.1 0.2 4.4e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor SPX PF03105.14 EMR65269.1 - 0.02 14.6 13.2 0.099 12.4 2.5 2.2 2 0 0 2 2 2 0 SPX domain DUF4613 PF15390.1 EMR65269.1 - 1.2 7.2 7.7 1.8 6.6 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) FTA4 PF13093.1 EMR65270.1 - 8.4e-52 175.6 0.0 1.1e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 UCR_14kD PF02271.11 EMR65270.1 - 2.3 8.0 5.3 0.55 10.0 0.1 2.3 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex 14kD subunit KfrA_N PF11740.3 EMR65270.1 - 4 7.9 13.2 9.2 6.7 1.2 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term p450 PF00067.17 EMR65271.1 - 7.3e-05 21.4 0.0 0.0061 15.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 ATP-synt_ab_C PF00306.22 EMR65271.1 - 0.13 12.7 0.1 0.34 11.3 0.1 1.8 1 1 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain Beta-lactamase PF00144.19 EMR65273.1 - 8.4e-50 169.6 0.0 1.2e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EMR65273.1 - 6.3e-06 25.9 0.1 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase2 PF13354.1 EMR65273.1 - 0.00051 19.5 0.0 0.0071 15.8 0.0 2.5 3 0 0 3 3 3 1 Beta-lactamase enzyme family DUF3320 PF11784.3 EMR65273.1 - 0.13 11.8 0.2 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) Pkip-1 PF06878.6 EMR65273.1 - 0.19 11.5 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Pkip-1 protein CoA_transf_3 PF02515.12 EMR65274.1 - 6.9e-30 103.7 0.0 5.9e-29 100.6 0.0 2.2 2 0 0 2 2 2 1 CoA-transferase family III bZIP_1 PF00170.16 EMR65274.1 - 0.00019 21.2 1.4 0.0005 19.9 1.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF2285 PF10074.4 EMR65274.1 - 0.0016 18.7 1.7 0.095 13.0 0.0 2.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2285) Dynamin_N PF00350.18 EMR65274.1 - 0.19 11.5 1.1 2.7 7.7 0.7 2.2 2 0 0 2 2 2 0 Dynamin family IncA PF04156.9 EMR65274.1 - 2.8 7.5 5.4 3 7.4 2.2 2.1 3 0 0 3 3 3 0 IncA protein TMPIT PF07851.8 EMR65274.1 - 3.9 6.4 3.8 6.4 5.7 2.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein bZIP_2 PF07716.10 EMR65274.1 - 7.7 6.4 16.0 0.021 14.6 3.8 2.1 2 0 0 2 2 2 0 Basic region leucine zipper UBA_3 PF09288.5 EMR65275.1 - 0.018 14.6 0.0 0.098 12.2 0.0 2.0 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Retrotrans_gag PF03732.12 EMR65275.1 - 0.042 13.9 1.8 0.076 13.1 0.4 2.2 2 1 0 2 2 2 0 Retrotransposon gag protein GST_C PF00043.20 EMR65275.1 - 0.12 12.3 0.1 0.35 10.8 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_3 PF00933.16 EMR65276.1 - 9.1e-81 271.1 0.0 1.3e-80 270.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR65276.1 - 5e-71 238.8 0.0 1.4e-70 237.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR65276.1 - 6.4e-25 86.8 0.2 1.5e-24 85.7 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EMR65276.1 - 3.9e-12 46.0 0.1 7.1e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Peptidase_C2 PF00648.16 EMR65277.1 - 4e-56 190.2 2.7 1.5e-37 129.2 0.8 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Syndecan PF01034.15 EMR65278.1 - 0.008 15.8 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 Syndecan domain Yip1 PF04893.12 EMR65278.1 - 0.056 12.9 0.0 0.079 12.4 0.0 1.1 1 0 0 1 1 1 0 Yip1 domain DUF1191 PF06697.7 EMR65278.1 - 0.07 11.9 0.0 0.091 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Phage_HK97_TLTM PF06120.6 EMR65278.1 - 0.12 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein DUF1517 PF07466.6 EMR65278.1 - 0.12 11.3 0.0 0.12 11.3 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1517) Herpes_gE PF02480.11 EMR65278.1 - 0.16 10.1 0.0 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E P12 PF12669.2 EMR65278.1 - 0.17 12.1 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF605 PF04652.11 EMR65278.1 - 0.39 10.0 9.5 0.49 9.7 6.6 1.3 1 0 0 1 1 1 0 Vta1 like Shisa PF13908.1 EMR65278.1 - 3.1 7.9 7.2 1.8e+02 2.1 5.0 2.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Methyltransf_11 PF08241.7 EMR65279.1 - 5.2e-23 81.3 0.0 7.9e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR65279.1 - 1.3e-19 70.2 0.0 1.8e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR65279.1 - 5.8e-16 58.6 0.0 9.1e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR65279.1 - 6.2e-16 58.9 0.0 1e-15 58.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR65279.1 - 9.7e-15 54.6 0.0 1.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR65279.1 - 3.3e-14 53.1 0.0 5.5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR65279.1 - 1.8e-13 50.7 0.0 3.1e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR65279.1 - 2.1e-12 46.6 0.0 3.1e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EMR65279.1 - 3.5e-08 33.0 0.0 5.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EMR65279.1 - 1.8e-05 23.9 0.0 0.00015 20.8 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 EMR65279.1 - 1.8e-05 24.3 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EMR65279.1 - 0.00011 21.3 0.0 0.00022 20.3 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.11 EMR65279.1 - 0.00012 20.5 0.0 0.00019 19.9 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.1 EMR65279.1 - 0.00015 21.4 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EMR65279.1 - 0.0006 18.9 0.0 0.00086 18.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.7 EMR65279.1 - 0.0018 17.7 0.0 0.0043 16.4 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.14 EMR65279.1 - 0.0027 17.7 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase FmrO PF07091.6 EMR65279.1 - 0.0031 16.5 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_8 PF05148.10 EMR65279.1 - 0.0088 15.6 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase UPF0020 PF01170.13 EMR65279.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 NodS PF05401.6 EMR65279.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 1 0 1 1 1 0 Nodulation protein S (NodS) PrmA PF06325.8 EMR65279.1 - 0.02 14.0 0.1 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.13 EMR65279.1 - 0.023 14.0 0.0 3.1 7.0 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain NNMT_PNMT_TEMT PF01234.12 EMR65279.1 - 0.054 12.4 0.0 3.4 6.5 0.0 2.2 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.6 EMR65279.1 - 0.066 11.8 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Nol1_Nop2_Fmu PF01189.12 EMR65279.1 - 0.088 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 NOL1/NOP2/sun family 3HCDH_N PF02737.13 EMR65279.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sulfotransfer_3 PF13469.1 EMR65281.1 - 3.2e-06 28.1 0.6 5.5e-06 27.3 0.4 1.5 1 1 0 1 1 1 1 Sulfotransferase family CytB6-F_Fe-S PF08802.5 EMR65281.1 - 0.016 15.2 0.3 0.039 13.9 0.2 1.7 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit Decorin_bind PF02352.10 EMR65282.1 - 0.098 12.6 3.9 0.14 12.1 2.7 1.2 1 0 0 1 1 1 0 Decorin binding protein V-ATPase_G PF03179.10 EMR65282.1 - 5.6 7.3 12.6 15 5.8 2.7 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF883 PF05957.8 EMR65282.1 - 8.9 6.7 7.9 14 6.1 1.2 2.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) PRP1_N PF06424.7 EMR65283.1 - 2.9e-52 176.5 7.1 7.7e-52 175.1 4.9 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EMR65283.1 - 2.7e-35 117.6 48.2 0.00088 19.7 0.4 14.3 3 2 12 15 15 14 11 Tetratricopeptide repeat TPR_19 PF14559.1 EMR65283.1 - 4e-29 100.7 23.2 5.8e-10 39.3 0.9 9.7 6 2 2 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EMR65283.1 - 7e-25 87.1 34.0 1.2e-06 28.9 0.1 9.0 5 2 5 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 EMR65283.1 - 2.1e-17 62.5 13.5 3.2e-06 26.7 0.1 7.6 5 2 1 7 7 7 3 TPR repeat TPR_2 PF07719.12 EMR65283.1 - 8.9e-14 50.2 20.0 0.073 13.0 0.0 10.7 11 1 1 12 12 11 4 Tetratricopeptide repeat TPR_8 PF13181.1 EMR65283.1 - 6.4e-09 34.9 0.2 0.17 11.7 0.0 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat NARP1 PF12569.3 EMR65283.1 - 1.7e-07 30.3 5.0 0.2 10.3 0.0 6.0 4 2 2 6 6 6 2 NMDA receptor-regulated protein 1 TPR_17 PF13431.1 EMR65283.1 - 1.9e-07 30.7 9.4 0.5 10.7 0.0 9.1 11 1 0 11 11 7 1 Tetratricopeptide repeat TPR_15 PF13429.1 EMR65283.1 - 2e-07 30.3 27.0 0.007 15.4 2.2 7.0 2 2 3 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EMR65283.1 - 7.7e-07 29.1 0.5 0.099 12.7 0.0 5.5 5 2 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EMR65283.1 - 1.4e-06 27.6 4.4 0.1 12.2 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMR65283.1 - 4.8e-06 26.4 16.9 0.04 13.8 0.0 7.3 8 2 1 9 9 8 2 Tetratricopeptide repeat Suf PF05843.9 EMR65283.1 - 3.1e-05 23.8 0.2 1.2 8.7 0.0 5.1 4 1 1 6 6 6 1 Suppressor of forked protein (Suf) TPR_6 PF13174.1 EMR65283.1 - 4.8e-05 23.5 21.2 12 6.6 0.0 9.7 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMR65283.1 - 0.00092 18.8 5.3 11 6.1 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMR65283.1 - 0.001 18.8 0.1 0.001 18.8 0.1 5.5 4 1 2 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EMR65283.1 - 0.0026 16.7 0.8 0.0026 16.7 0.6 5.3 4 2 1 5 5 5 3 NRDE-2, necessary for RNA interference TPR_21 PF09976.4 EMR65283.1 - 0.0062 16.4 3.7 0.0062 16.4 2.5 4.8 5 1 1 6 6 3 2 Tetratricopeptide repeat ChAPs PF09295.5 EMR65283.1 - 0.028 13.1 1.0 0.13 11.0 0.2 2.1 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF3808 PF10300.4 EMR65283.1 - 0.21 10.1 4.7 3.9 5.9 0.0 3.8 3 1 1 5 5 5 0 Protein of unknown function (DUF3808) TPR_10 PF13374.1 EMR65283.1 - 1.7 8.6 12.9 4.8 7.2 0.1 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat RrnaAD PF00398.15 EMR65284.1 - 1.5e-59 201.2 0.0 2.1e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EMR65284.1 - 4e-10 39.7 0.0 6.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR65284.1 - 3.4e-07 30.8 0.0 7.1e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR65284.1 - 3.9e-06 26.3 0.0 6.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EMR65284.1 - 5e-05 22.9 0.0 0.0001 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR65284.1 - 0.00017 21.3 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR65284.1 - 0.00019 21.8 0.0 0.00038 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMR65284.1 - 0.0004 19.9 0.0 0.00072 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EMR65284.1 - 0.00065 18.8 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EMR65284.1 - 0.0044 17.4 0.0 0.0098 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EMR65284.1 - 0.0085 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_2 PF00891.13 EMR65284.1 - 0.02 14.0 0.0 0.041 13.0 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.8 EMR65284.1 - 0.045 12.8 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EMR65284.1 - 0.05 12.6 0.0 0.098 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EMR65284.1 - 0.059 12.4 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMR65284.1 - 0.061 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EMR65284.1 - 0.15 11.4 0.0 0.5 9.7 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW DREV PF05219.7 EMR65284.1 - 0.16 10.7 0.0 0.41 9.4 0.0 1.6 2 0 0 2 2 2 0 DREV methyltransferase FAD_binding_3 PF01494.14 EMR65285.1 - 8.9e-22 77.6 0.0 4e-21 75.4 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR65285.1 - 1e-06 27.9 0.2 0.0018 17.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR65285.1 - 3.9e-05 23.9 0.7 0.0037 17.6 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR65285.1 - 0.00042 19.3 0.2 0.0062 15.5 0.1 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMR65285.1 - 0.00045 20.1 0.0 0.0015 18.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR65285.1 - 0.022 14.6 0.1 0.05 13.4 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR65285.1 - 0.082 12.9 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMR65286.1 - 5.1e-50 170.5 0.2 6.1e-50 170.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EMR65286.1 - 0.0046 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain IF-2B PF01008.12 EMR65287.1 - 5.4e-22 78.0 0.0 6.2e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Aldo_ket_red PF00248.16 EMR65288.1 - 1.3e-44 152.1 0.0 1.6e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 EMR65289.1 - 1.2e-31 109.8 0.0 1.4e-15 56.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 SprT-like PF10263.4 EMR65290.1 - 2.5e-41 140.9 4.9 4e-41 140.2 3.4 1.3 1 0 0 1 1 1 1 SprT-like family DASH_Dam1 PF08653.5 EMR65291.1 - 2.7e-27 94.2 1.9 4e-27 93.7 1.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Silic_transp PF03842.8 EMR65291.1 - 0.029 12.4 0.0 0.034 12.2 0.0 1.1 1 0 0 1 1 1 0 Silicon transporter Coatomer_WDAD PF04053.9 EMR65292.1 - 2.3e-149 497.9 0.0 4.3e-149 497.0 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 EMR65292.1 - 5.9e-84 282.0 0.0 8.5e-84 281.5 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EMR65292.1 - 3.1e-50 166.3 15.4 5.4e-09 35.6 0.0 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat Clathrin PF00637.15 EMR65292.1 - 0.011 15.2 0.2 0.063 12.8 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS Nup160 PF11715.3 EMR65292.1 - 0.082 11.0 5.6 0.38 8.8 0.1 3.3 2 1 2 4 4 4 0 Nucleoporin Nup120/160 SnoaL PF07366.7 EMR65293.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase HIT PF01230.18 EMR65294.1 - 1.8e-22 79.7 0.1 2.6e-22 79.2 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EMR65294.1 - 2.4e-13 50.3 0.0 3.2e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EMR65294.1 - 3.7e-05 23.3 0.0 5.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.1 EMR65294.1 - 0.054 13.5 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Fez1 PF06818.10 EMR65295.1 - 0.00011 22.2 32.5 0.00027 21.0 13.3 2.2 1 1 1 2 2 2 2 Fez1 Tropomyosin PF00261.15 EMR65295.1 - 0.002 17.2 21.6 0.002 17.2 15.0 2.5 1 1 1 2 2 2 1 Tropomyosin WEMBL PF05701.6 EMR65295.1 - 0.0026 16.2 35.3 0.0057 15.1 24.4 1.5 1 1 0 1 1 1 1 Weak chloroplast movement under blue light AAA_13 PF13166.1 EMR65295.1 - 0.0041 15.6 25.7 0.0055 15.2 17.8 1.1 1 0 0 1 1 1 1 AAA domain TMF_DNA_bd PF12329.3 EMR65295.1 - 0.0051 16.5 7.0 0.0051 16.5 4.9 4.2 1 1 1 2 2 1 1 TATA element modulatory factor 1 DNA binding Pox_A_type_inc PF04508.7 EMR65295.1 - 0.037 13.7 9.0 0.34 10.8 0.1 4.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat bZIP_2 PF07716.10 EMR65295.1 - 0.068 13.0 0.4 0.068 13.0 0.3 5.3 3 2 2 5 5 5 0 Basic region leucine zipper DUF4636 PF15468.1 EMR65295.1 - 0.22 10.9 0.1 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4636) ATG16 PF08614.6 EMR65295.1 - 0.29 10.9 32.0 9.3 6.0 11.3 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Atg14 PF10186.4 EMR65295.1 - 0.41 9.5 36.9 0.083 11.8 8.9 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 GAS PF13851.1 EMR65295.1 - 0.53 9.4 34.3 1.6 7.9 8.3 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.6 EMR65295.1 - 0.76 9.7 11.6 0.27 11.1 0.2 4.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Peptidase_S64 PF08192.6 EMR65295.1 - 0.86 7.8 14.3 1 7.5 9.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 CENP-F_leu_zip PF10473.4 EMR65295.1 - 0.88 9.4 36.0 0.91 9.3 7.8 2.6 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_27 PF13514.1 EMR65295.1 - 0.96 7.0 32.3 1.2 6.7 21.8 1.5 1 1 0 1 1 1 0 AAA domain Spc7 PF08317.6 EMR65295.1 - 1.3 7.6 33.0 0.45 9.1 13.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein TSC22 PF01166.13 EMR65295.1 - 1.5 8.8 17.0 3.4 7.7 1.1 4.6 1 1 2 4 4 4 0 TSC-22/dip/bun family DUF3584 PF12128.3 EMR65295.1 - 1.5 6.0 36.1 0.047 11.0 18.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) IncA PF04156.9 EMR65295.1 - 1.6 8.2 37.5 4.2 6.9 14.7 2.7 1 1 2 3 3 3 0 IncA protein Tropomyosin_1 PF12718.2 EMR65295.1 - 2.3 8.0 39.7 0.074 12.8 9.1 2.3 1 1 1 2 2 2 0 Tropomyosin like Fib_alpha PF08702.5 EMR65295.1 - 2.9 7.9 19.7 0.37 10.9 0.4 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Filament PF00038.16 EMR65295.1 - 3.4 7.0 31.9 24 4.2 22.1 1.9 1 1 0 1 1 1 0 Intermediate filament protein Sulfatase_C PF14707.1 EMR65295.1 - 4.9 7.4 7.9 1.6 9.0 1.6 2.4 1 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Prominin PF05478.6 EMR65295.1 - 6.2 4.2 16.9 8.8 3.7 11.7 1.2 1 0 0 1 1 1 0 Prominin TPR_MLP1_2 PF07926.7 EMR65295.1 - 8.3 6.1 41.7 9.3 6.0 6.1 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein SAC3_GANP PF03399.11 EMR65296.1 - 6e-26 91.2 0.0 1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EMR65296.1 - 2e-19 69.7 0.0 2.9e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Sel1 PF08238.7 EMR65297.1 - 4.3e-15 55.7 22.9 2.1e-08 34.5 0.1 6.9 7 0 0 7 7 7 4 Sel1 repeat TPR_11 PF13414.1 EMR65297.1 - 0.86 9.2 3.9 3.6 7.3 0.0 3.1 3 0 0 3 3 3 0 TPR repeat N6-adenineMlase PF10237.4 EMR65298.1 - 2.1e-57 193.2 0.0 2.6e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Mog1 PF04603.7 EMR65299.1 - 2.7e-16 59.8 0.0 6.8e-14 52.0 0.0 2.0 2 0 0 2 2 2 2 Ran-interacting Mog1 protein Peptidase_S8 PF00082.17 EMR65300.1 - 2e-43 148.5 12.9 3e-43 148.0 8.9 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMR65300.1 - 1.4e-13 51.1 0.0 2.6e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Lactamase_B PF00753.22 EMR65301.1 - 3.1e-25 88.9 3.6 4.2e-25 88.5 2.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMR65301.1 - 1.5e-05 24.6 0.1 2.4e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMR65301.1 - 0.026 14.2 0.1 0.05 13.3 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PCI PF01399.22 EMR65302.1 - 5.1e-06 26.7 0.0 1.6e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 PCI domain RE_TaqI PF09573.5 EMR65302.1 - 0.032 13.3 0.2 0.061 12.4 0.1 1.4 1 0 0 1 1 1 0 TaqI restriction endonuclease Apc5 PF12862.2 EMR65302.1 - 0.49 10.2 5.8 2.3 8.1 1.4 2.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 CRAL_TRIO PF00650.15 EMR65303.1 - 4.2e-41 140.1 0.0 7e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMR65303.1 - 1.2e-14 54.2 1.9 1.4e-14 53.9 0.1 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EMR65303.1 - 3.3e-10 40.0 0.0 8.8e-10 38.6 0.0 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Gaa1 PF04114.9 EMR65304.1 - 1.9e-92 310.5 3.5 6.2e-88 295.6 0.0 2.3 2 1 0 2 2 2 2 Gaa1-like, GPI transamidase component Calici_PP_N PF08405.6 EMR65304.1 - 0.17 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal Glyco_hydro_17 PF00332.13 EMR65305.1 - 5.7e-07 28.8 0.2 1.4e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.8 EMR65305.1 - 0.0039 16.0 0.0 0.22 10.2 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 53 Aconitase PF00330.15 EMR65306.1 - 1.2e-171 571.2 0.0 2.1e-171 570.5 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMR65306.1 - 3.8e-45 153.1 0.0 6.8e-45 152.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ytp1 PF10355.4 EMR65307.1 - 4.2e-107 357.3 5.6 6.8e-107 356.6 3.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EMR65307.1 - 1.9e-34 117.4 5.7 1.9e-34 117.4 4.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF3481 PF11980.3 EMR65307.1 - 1.8 8.4 5.5 2.5 7.9 0.0 3.5 4 1 1 5 5 5 0 Domain of unknown function (DUF3481) Xol-1_N PF09108.5 EMR65308.1 - 0.039 13.6 0.1 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 Switch protein XOL-1, N-terminal CytochromB561_N PF09786.4 EMR65308.1 - 0.19 10.1 11.7 0.29 9.5 8.1 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Mito_carr PF00153.22 EMR65309.1 - 3.2e-28 97.2 1.2 2.1e-14 52.9 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF606 PF04657.8 EMR65309.1 - 0.013 15.5 2.4 0.21 11.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF606 DUF3054 PF11255.3 EMR65309.1 - 0.19 11.5 2.1 0.2 11.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) Lgl_C PF08596.5 EMR65310.1 - 1.8e-117 392.1 0.0 2.8e-117 391.5 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EMR65310.1 - 2.8e-06 26.9 2.0 0.0025 17.6 0.1 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat NAD_binding_10 PF13460.1 EMR65312.1 - 6.1e-12 45.9 0.0 8.3e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR65312.1 - 4.9e-07 29.2 0.0 6.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EMR65312.1 - 1e-06 28.3 0.2 2.2e-06 27.3 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR65312.1 - 1.6e-05 23.7 0.1 0.00011 20.9 0.0 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EMR65312.1 - 0.0036 16.2 0.1 0.016 14.1 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain zf-C2H2_jaz PF12171.3 EMR65313.1 - 1.9e-08 34.2 0.2 1.9e-08 34.2 0.1 1.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMR65313.1 - 0.031 14.4 0.1 0.067 13.4 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMR65313.1 - 0.049 13.7 0.0 0.09 12.8 0.0 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EMR65313.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EMR65313.1 - 0.11 12.9 0.8 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger SNF2_N PF00176.18 EMR65314.1 - 3.6e-68 229.5 0.0 4.9e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EMR65314.1 - 9.9e-61 204.9 0.6 3.9e-60 203.0 0.4 1.9 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 EMR65314.1 - 7.2e-13 48.2 0.0 2.8e-12 46.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EMR65314.1 - 1.5e-06 27.2 0.0 5e-06 25.5 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EMR65314.1 - 9e-05 22.3 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMR65314.1 - 0.12 12.4 0.1 1.3 9.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain Peptidase_S66 PF02016.10 EMR65316.1 - 1.3e-51 175.2 0.0 1.7e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 LD-carboxypeptidase Glucan_synthase PF02364.10 EMR65317.1 - 0 1449.0 0.0 0 1448.2 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EMR65317.1 - 4.4e-39 133.0 0.1 1.1e-38 131.7 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 dsDNA_bind PF01984.15 EMR65318.1 - 0.63 10.0 5.5 0.31 11.0 0.8 2.1 2 0 0 2 2 2 0 Double-stranded DNA-binding domain UDP-g_GGTase PF06427.6 EMR65319.1 - 1.5e-62 210.7 0.0 2.8e-62 209.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EMR65319.1 - 6.4e-05 22.4 0.7 0.00014 21.2 0.4 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Aminotran_1_2 PF00155.16 EMR65320.1 - 2.3e-39 135.4 0.0 2.7e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMR65320.1 - 0.032 12.5 0.0 0.05 11.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Acetyltransf_7 PF13508.1 EMR65321.1 - 8.1e-07 29.1 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR65321.1 - 1e-06 28.6 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMR65321.1 - 0.0019 18.2 0.0 0.0027 17.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR65321.1 - 0.003 17.4 0.0 0.0046 16.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Rhomboid PF01694.17 EMR65322.1 - 1e-14 54.8 13.1 1e-14 54.8 9.1 1.6 2 0 0 2 2 2 1 Rhomboid family AAA PF00004.24 EMR65323.1 - 4.5e-10 39.8 0.0 1.9e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMR65323.1 - 0.035 13.8 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMR65323.1 - 0.058 14.2 0.1 0.11 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain UCH PF00443.24 EMR65324.1 - 2.9e-30 105.3 7.3 1.3e-20 73.6 1.6 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMR65324.1 - 1.8e-11 44.0 7.8 5.6e-11 42.4 1.8 2.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMR65324.1 - 4.9e-05 23.3 0.4 4.9e-05 23.3 0.3 2.4 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Rsa3 PF14615.1 EMR65325.1 - 7.6e-20 69.9 0.4 1.1e-19 69.4 0.3 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 ELH PF02323.10 EMR65325.1 - 0.029 13.5 0.1 0.029 13.5 0.1 1.2 1 0 0 1 1 1 0 Egg-laying hormone precursor DUF3869 PF12985.2 EMR65326.1 - 0.33 11.4 5.9 0.078 13.4 1.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3869) Ribosomal_S8e PF01201.17 EMR65327.1 - 6.8e-47 158.9 2.1 7.9e-47 158.7 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EMR65327.1 - 0.092 13.0 1.6 0.11 12.7 0.2 1.9 2 0 0 2 2 2 0 Small acidic protein family AA_permease_2 PF13520.1 EMR65328.1 - 9.1e-54 182.6 45.2 1e-53 182.4 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMR65328.1 - 8.1e-28 96.9 35.5 1e-27 96.6 24.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3355 PF11835.3 EMR65328.1 - 0.2 11.4 0.7 0.32 10.7 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) Ctf8 PF09696.5 EMR65329.1 - 1.8e-22 79.3 0.5 2e-22 79.2 0.3 1.0 1 0 0 1 1 1 1 Ctf8 Ribosomal_S6e PF01092.14 EMR65330.1 - 7.1e-61 203.4 0.4 1.3e-60 202.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Cadherin_C PF01049.12 EMR65330.1 - 0.11 12.4 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic region WW PF00397.21 EMR65331.1 - 3.6e-07 29.9 0.3 7.3e-07 28.9 0.2 1.6 1 0 0 1 1 1 1 WW domain Tubulin PF00091.20 EMR65332.1 - 1.4e-70 237.5 0.0 2.2e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMR65332.1 - 1.9e-47 160.3 0.0 3.3e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EMR65332.1 - 0.0024 17.3 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Cellulase PF00150.13 EMR65334.1 - 3.3e-54 184.0 4.3 3.9e-54 183.7 3.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short_C2 PF13561.1 EMR65335.1 - 3.3e-28 99.0 0.5 4e-28 98.8 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR65335.1 - 4.8e-24 85.1 2.1 6.7e-24 84.6 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR65335.1 - 1.9e-12 47.2 1.1 2.8e-12 46.6 0.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR65335.1 - 0.002 17.5 0.5 0.0035 16.8 0.4 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 EMR65335.1 - 0.019 14.5 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.21 EMR65335.1 - 0.03 13.8 0.2 0.52 9.8 0.1 2.4 2 1 0 2 2 2 0 Zinc-binding dehydrogenase TFIID_30kDa PF03540.8 EMR65336.1 - 2.2e-24 85.0 0.4 4.2e-24 84.1 0.3 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 EMR65336.1 - 0.046 14.1 0.9 0.094 13.1 0.6 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Pribosyltran_N PF13793.1 EMR65337.1 - 1.3e-43 147.3 1.4 6.1e-42 142.0 0.1 2.9 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EMR65337.1 - 6.3e-39 133.6 6.2 1.8e-33 115.8 3.1 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EMR65337.1 - 2.2e-12 46.7 1.3 1.1e-11 44.4 0.5 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EMR65337.1 - 0.0033 16.6 0.5 0.0058 15.8 0.3 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF218 PF02698.12 EMR65337.1 - 0.059 12.8 0.1 0.32 10.4 0.0 2.0 1 1 0 1 1 1 0 DUF218 domain Chlorosome_CsmC PF11098.3 EMR65337.1 - 0.17 11.5 5.0 0.27 10.9 2.9 1.8 1 1 1 2 2 2 0 Chlorosome envelope protein C AIP3 PF03915.8 EMR65338.1 - 5.3e-160 532.9 16.0 6.3e-160 532.7 11.1 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 DUF3348 PF11828.3 EMR65338.1 - 0.0044 16.4 1.5 0.011 15.2 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3348) Lectin_N PF03954.9 EMR65338.1 - 0.0047 16.3 1.7 0.0047 16.3 1.1 2.5 2 1 0 2 2 2 1 Hepatic lectin, N-terminal domain Baculo_p24 PF05073.7 EMR65338.1 - 0.031 13.8 3.1 0.1 12.1 0.0 2.7 3 0 0 3 3 3 0 Baculovirus P24 capsid protein Thymidylat_synt PF00303.14 EMR65338.1 - 0.055 12.4 0.2 0.41 9.6 0.0 2.1 2 0 0 2 2 2 0 Thymidylate synthase DUF3138 PF11336.3 EMR65338.1 - 0.14 10.3 0.9 0.2 9.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FlaC_arch PF05377.6 EMR65338.1 - 0.33 10.8 7.6 96 2.9 0.1 5.4 3 3 2 6 6 6 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 EMR65338.1 - 0.98 9.2 10.9 0.5 10.1 1.2 3.8 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) TraF_2 PF13729.1 EMR65338.1 - 5.6 5.6 10.9 1.2 7.9 0.3 3.5 2 1 0 3 3 3 0 F plasmid transfer operon, TraF, protein DUF4510 PF14971.1 EMR65338.1 - 7.7 6.6 11.9 0.11 12.6 0.6 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4510) DUF2763 PF10961.3 EMR65339.1 - 0.32 11.4 4.0 0.25 11.7 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2763) Epimerase PF01370.16 EMR65340.1 - 1.4e-18 67.2 0.0 1.9e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR65340.1 - 7.6e-13 47.7 0.0 1e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMR65340.1 - 3.6e-12 46.6 0.3 6.6e-12 45.8 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMR65340.1 - 5.2e-10 39.5 0.3 1.6e-09 37.9 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EMR65340.1 - 9.6e-09 34.5 0.0 2.5e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EMR65340.1 - 3.4e-05 23.5 0.1 6.7e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMR65340.1 - 0.00032 19.6 0.0 0.00043 19.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EMR65340.1 - 0.00052 19.3 0.0 0.033 13.4 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 EMR65340.1 - 0.091 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ribosomal_S19 PF00203.16 EMR65341.1 - 3.9e-22 77.6 0.0 5.8e-22 77.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Ufd2P_core PF10408.4 EMR65342.1 - 1e-177 592.2 0.0 1.2e-177 592.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EMR65342.1 - 1e-19 70.2 0.4 2.9e-19 68.7 0.2 1.8 1 0 0 1 1 1 1 U-box domain Med9 PF07544.8 EMR65342.1 - 0.2 11.4 1.4 8.4 6.2 0.0 3.2 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 RabGAP-TBC PF00566.13 EMR65343.1 - 1.6e-46 158.5 0.4 1.1e-44 152.4 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Microtub_assoc PF07989.6 EMR65343.1 - 0.0033 17.2 14.7 0.095 12.5 4.1 3.2 2 0 0 2 2 2 2 Microtubule associated IFP_35_N PF07334.8 EMR65343.1 - 0.2 11.6 8.8 0.85 9.6 0.9 3.2 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus HALZ PF02183.13 EMR65343.1 - 2.6 7.8 14.2 1.4 8.7 0.8 3.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF4131 PF13567.1 EMR65344.1 - 0.16 11.3 5.2 0.24 10.7 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) EF-hand_4 PF12763.2 EMR65346.1 - 2.6e-30 104.2 0.0 1.7e-11 43.7 0.0 3.6 2 1 1 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EMR65346.1 - 9.9e-10 38.4 0.2 0.0001 22.3 0.0 4.3 3 2 3 6 6 5 3 EF-hand domain pair UBA PF00627.26 EMR65346.1 - 2.5e-07 30.3 0.0 5.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 EMR65346.1 - 2.5e-06 26.3 0.2 6.4 6.3 0.0 5.7 6 0 0 6 6 6 0 EF hand EF-hand_6 PF13405.1 EMR65346.1 - 2.6e-05 23.7 1.1 0.23 11.4 0.1 5.1 5 1 1 6 6 5 1 EF-hand domain CENP-F_leu_zip PF10473.4 EMR65346.1 - 0.00054 19.8 12.7 0.00054 19.8 8.8 2.7 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rab5-bind PF09311.6 EMR65346.1 - 0.00087 19.2 7.2 0.00087 19.2 5.0 3.2 1 1 2 3 3 3 1 Rabaptin-like protein DUF1664 PF07889.7 EMR65346.1 - 0.0015 18.3 5.6 0.0015 18.3 3.9 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) TBPIP PF07106.8 EMR65346.1 - 0.002 17.6 9.9 0.002 17.6 6.9 2.5 1 1 1 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 EMR65346.1 - 0.0026 17.4 23.2 0.083 12.5 5.4 2.2 2 0 0 2 2 2 2 Mnd1 family IncA PF04156.9 EMR65346.1 - 0.006 16.1 25.6 0.006 16.1 17.7 2.2 1 1 1 2 2 2 1 IncA protein ATG16 PF08614.6 EMR65346.1 - 0.0084 15.9 30.2 0.097 12.4 8.8 2.5 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) WEMBL PF05701.6 EMR65346.1 - 0.016 13.6 23.5 0.024 13.1 16.3 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 EMR65346.1 - 0.023 12.4 27.3 0.026 12.2 13.2 1.9 1 1 1 2 2 2 0 Myosin tail AAA_27 PF13514.1 EMR65346.1 - 0.046 11.4 18.9 0.073 10.7 13.1 1.2 1 0 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.3 EMR65346.1 - 0.052 13.2 28.5 0.18 11.5 4.3 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3584 PF12128.3 EMR65346.1 - 0.059 10.7 31.3 0.082 10.2 21.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EMR65346.1 - 0.085 11.3 23.5 0.12 10.7 16.3 1.1 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 EMR65346.1 - 0.15 11.8 31.8 1.7 8.4 14.5 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 EMR65346.1 - 0.24 10.0 28.6 0.91 8.1 5.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EMR65346.1 - 0.24 10.5 5.8 0.26 10.4 3.0 1.7 1 1 0 1 1 1 0 Reovirus sigma C capsid protein HrpB7 PF09486.5 EMR65346.1 - 0.39 10.6 12.3 0.67 9.8 8.2 1.7 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF3450 PF11932.3 EMR65346.1 - 0.44 9.7 29.6 0.15 11.2 8.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) GAS PF13851.1 EMR65346.1 - 0.45 9.6 29.8 0.055 12.6 12.3 2.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding MAD PF05557.8 EMR65346.1 - 0.67 7.9 26.0 0.96 7.4 18.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Seryl_tRNA_N PF02403.17 EMR65346.1 - 0.68 9.9 30.0 1.4 9.0 6.5 3.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4047 PF13256.1 EMR65346.1 - 0.72 9.8 13.1 0.1 12.5 5.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) EzrA PF06160.7 EMR65346.1 - 0.76 7.8 23.8 0.065 11.4 11.8 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA FUSC PF04632.7 EMR65346.1 - 0.85 7.9 5.2 1.3 7.3 3.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6 PF04111.7 EMR65346.1 - 0.93 8.4 27.9 0.24 10.3 13.7 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 FH2 PF02181.18 EMR65346.1 - 1 8.1 19.6 0.22 10.3 4.0 2.3 1 1 1 2 2 2 0 Formin Homology 2 Domain Atg14 PF10186.4 EMR65346.1 - 1.2 8.0 32.1 1.7 7.4 9.4 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Lebercilin PF15619.1 EMR65346.1 - 1.3 8.3 30.3 3.3 7.0 21.0 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.16 EMR65346.1 - 2 7.7 27.1 3.3 7.1 6.2 2.1 1 1 1 2 2 2 0 Intermediate filament protein TMF_DNA_bd PF12329.3 EMR65346.1 - 4.1 7.2 36.5 2 8.3 6.9 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF812 PF05667.6 EMR65346.1 - 5.8 5.3 23.7 3.9 5.8 14.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DivIC PF04977.10 EMR65346.1 - 8.2 5.9 32.8 6.1 6.4 3.5 4.5 1 1 3 4 4 4 0 Septum formation initiator USP8_interact PF08941.5 EMR65347.1 - 0.036 13.3 2.7 0.052 12.8 1.9 1.3 1 0 0 1 1 1 0 USP8 interacting ECSIT PF06239.6 EMR65347.1 - 0.038 12.8 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway TMF_DNA_bd PF12329.3 EMR65347.1 - 0.065 13.0 5.9 0.13 12.0 0.5 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 EMR65347.1 - 0.082 13.2 9.5 0.15 12.4 1.9 2.5 1 1 1 2 2 2 0 SlyX UPF0242 PF06785.6 EMR65347.1 - 0.1 11.2 4.2 0.18 10.4 2.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) TerB PF05099.8 EMR65347.1 - 0.11 12.2 5.3 0.19 11.4 3.7 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TerB Mnd1 PF03962.10 EMR65347.1 - 0.14 11.8 5.4 0.18 11.4 3.8 1.3 1 0 0 1 1 1 0 Mnd1 family NPV_P10 PF05531.7 EMR65347.1 - 0.19 12.0 7.6 6 7.1 2.9 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.1 EMR65347.1 - 0.36 9.7 8.3 0.44 9.4 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Swi5 PF07061.6 EMR65347.1 - 0.42 10.4 4.1 1.5 8.6 1.8 2.2 1 1 1 2 2 2 0 Swi5 FUSC PF04632.7 EMR65347.1 - 0.49 8.7 5.1 0.54 8.6 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Adeno_PIX PF03955.9 EMR65347.1 - 0.7 10.4 5.2 1.5 9.3 1.6 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Cob_adeno_trans PF01923.13 EMR65347.1 - 0.79 9.4 6.2 3.7 7.3 0.5 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF1732 PF08340.6 EMR65347.1 - 0.88 9.4 8.0 1.3 8.8 2.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1732) DivIC PF04977.10 EMR65347.1 - 3.4 7.2 6.6 1.6 8.2 1.2 2.3 1 1 1 2 2 2 0 Septum formation initiator Phage_Gp23 PF10669.4 EMR65347.1 - 4.1 7.5 9.5 5.8 7.0 3.4 2.8 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) Phage_GP20 PF06810.6 EMR65347.1 - 7.2 6.0 10.9 7 6.0 1.1 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DNase_NucA_NucB PF14040.1 EMR65348.1 - 3.6e-28 98.0 0.9 6.9e-28 97.0 0.6 1.5 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB DUF913 PF06025.7 EMR65349.1 - 8.5e-111 370.3 0.0 8.5e-111 370.3 0.0 3.9 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) HECT PF00632.20 EMR65349.1 - 1.6e-94 316.6 0.0 2.7e-94 315.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EMR65349.1 - 1.4e-87 294.0 0.5 1.4e-87 294.0 0.4 3.4 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EMR65349.1 - 9.4e-32 109.1 8.8 9.4e-32 109.1 6.1 4.5 5 1 0 5 5 5 1 Domain of unknown function (DUF4414) Aida_N PF08910.5 EMR65352.1 - 0.012 15.7 0.9 0.015 15.5 0.6 1.2 1 0 0 1 1 1 0 Aida N-terminus PGBA_C PF15437.1 EMR65352.1 - 0.037 14.1 3.0 0.072 13.2 2.1 1.6 1 1 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal RP-C_C PF11800.3 EMR65352.1 - 0.053 13.2 2.3 0.066 12.9 1.6 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region PPP4R2 PF09184.6 EMR65352.1 - 0.12 11.8 5.3 0.13 11.7 3.7 1.0 1 0 0 1 1 1 0 PPP4R2 NOC3p PF07540.6 EMR65352.1 - 0.12 12.6 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Nucleolar complex-associated protein Ndc1_Nup PF09531.5 EMR65352.1 - 0.22 9.8 2.2 0.27 9.6 1.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup p450 PF00067.17 EMR65353.1 - 4.2e-19 68.4 0.1 1.8e-18 66.3 0.1 1.8 1 1 0 1 1 1 1 Cytochrome P450 GPI2 PF06432.6 EMR65354.1 - 9.8e-121 402.4 4.2 1.4e-120 401.9 2.9 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase VCBS PF13517.1 EMR65355.1 - 0.00015 22.0 10.6 0.022 15.1 2.5 4.4 1 1 2 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EMR65355.1 - 0.00019 21.0 0.7 0.4 10.4 0.1 3.1 3 0 0 3 3 3 2 FG-GAP repeat TcdB_toxin_midN PF12256.3 EMR65355.1 - 0.00052 19.5 0.1 0.47 9.8 0.0 2.3 2 0 0 2 2 2 2 Insecticide toxin TcdB middle/N-terminal region P_proprotein PF01483.15 EMR65355.1 - 0.0077 15.9 0.8 12 5.8 0.0 4.0 2 1 1 4 4 4 1 Proprotein convertase P-domain FaeA PF04703.7 EMR65355.1 - 0.027 14.6 0.8 16 5.7 0.0 3.2 3 0 0 3 3 3 0 FaeA-like protein DUF756 PF05506.7 EMR65355.1 - 0.037 14.4 4.9 13 6.3 0.1 4.2 3 2 2 5 5 5 0 Domain of unknown function (DUF756) EF-hand_6 PF13405.1 EMR65355.1 - 0.1 12.5 0.1 3.4 7.7 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 EMR65355.1 - 0.1 11.9 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 EF hand adh_short PF00106.20 EMR65356.1 - 2.5e-06 27.5 0.3 0.00047 20.1 0.0 2.6 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EMR65356.1 - 0.034 13.8 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 KR domain Annexin PF00191.15 EMR65357.1 - 6e-17 61.3 0.0 0.0018 18.1 0.0 4.5 4 0 0 4 4 4 4 Annexin Cyt-b5 PF00173.23 EMR65358.1 - 2.9e-16 59.0 0.0 4.2e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MFS_1 PF07690.11 EMR65359.1 - 1.3e-11 43.8 30.3 1.3e-11 43.8 21.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR65359.1 - 1.1e-08 34.0 9.8 1.1e-08 34.0 6.8 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter UNC-93 PF05978.11 EMR65359.1 - 3.2e-08 33.2 3.5 9.5e-08 31.6 2.4 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Amidohydro_2 PF04909.9 EMR65360.1 - 6.4e-39 134.1 0.8 8.6e-39 133.7 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase DAO PF01266.19 EMR65361.1 - 3.9e-50 170.7 0.0 4.5e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR65361.1 - 0.0014 18.5 0.0 0.34 10.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR65361.1 - 0.0018 18.0 0.2 0.21 11.3 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding F420_oxidored PF03807.12 EMR65361.1 - 0.0057 17.0 0.1 0.02 15.2 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.1 EMR65361.1 - 0.03 14.3 0.0 6.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EMR65361.1 - 0.13 12.0 0.0 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 ThiF family Trp_halogenase PF04820.9 EMR65361.1 - 0.14 10.7 0.1 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 EMR65361.1 - 0.19 10.5 0.0 2.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FHA PF00498.21 EMR65362.1 - 1.1e-09 38.2 0.0 2.5e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 EMR65362.1 - 0.2 11.8 0.3 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain RRM_1 PF00076.17 EMR65363.1 - 9.7e-17 60.3 0.0 1.4e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR65363.1 - 1.8e-13 50.2 0.0 3.4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR65363.1 - 1.3e-08 34.5 0.0 2.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L31 PF09784.4 EMR65364.1 - 4.2e-46 155.2 2.7 4.6e-46 155.1 1.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Histone_HNS PF00816.16 EMR65364.1 - 0.076 13.5 0.5 0.1 13.1 0.4 1.2 1 0 0 1 1 1 0 H-NS histone family TPR_1 PF00515.23 EMR65365.1 - 5.1e-41 136.6 15.1 2.2e-07 30.1 0.0 9.8 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.1 EMR65365.1 - 2.7e-38 129.4 30.6 2.1e-12 46.5 1.1 7.8 5 3 2 7 7 7 7 TPR repeat TPR_2 PF07719.12 EMR65365.1 - 2.5e-37 123.7 24.5 7.3e-06 25.5 0.1 10.5 11 0 0 11 11 10 8 Tetratricopeptide repeat Apc3 PF12895.2 EMR65365.1 - 2.1e-27 95.0 33.2 2e-21 75.9 0.5 5.4 4 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EMR65365.1 - 8.7e-26 87.7 10.5 0.0003 20.3 0.1 9.2 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 EMR65365.1 - 3.6e-25 87.6 28.0 3.7e-06 26.7 1.2 7.7 6 2 1 7 7 7 7 Tetratricopeptide repeat TPR_19 PF14559.1 EMR65365.1 - 5.7e-22 77.8 17.6 6.7e-08 32.7 3.5 6.8 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMR65365.1 - 7.4e-22 75.6 10.2 0.0097 16.0 0.0 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 EMR65365.1 - 2.2e-20 72.7 32.2 7.2e-06 26.5 0.3 8.1 5 3 3 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 EMR65365.1 - 4e-20 70.4 11.8 0.05 14.2 1.2 10.3 4 2 6 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 EMR65365.1 - 3e-16 57.8 13.7 0.0033 17.0 0.0 8.8 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 EMR65365.1 - 4.9e-12 45.4 15.7 0.48 11.0 0.0 10.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMR65365.1 - 8.3e-06 25.5 12.7 0.13 12.1 0.5 6.1 4 2 1 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.4 EMR65365.1 - 0.0013 18.1 5.8 4.7 6.6 2.7 3.8 2 2 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) APP_E2 PF12925.2 EMR65365.1 - 0.061 12.8 10.4 14 5.2 0.0 4.6 3 2 1 4 4 4 0 E2 domain of amyloid precursor protein Fis1_TPR_C PF14853.1 EMR65365.1 - 0.075 12.9 0.3 0.075 12.9 0.2 3.6 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 EMR65365.1 - 0.15 12.5 6.6 8 7.2 0.3 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Histone PF00125.19 EMR65366.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EMR65366.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EMR65366.1 - 0.00012 22.1 0.1 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMR65366.1 - 0.00033 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EMR65366.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EMR65366.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF3439 PF11921.3 EMR65367.1 - 3.1 7.5 13.6 0.055 13.2 4.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) NAD_binding_1 PF00175.16 EMR65368.1 - 7.9e-27 93.9 0.0 1.3e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMR65368.1 - 2.1e-26 91.9 0.0 3.2e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EMR65368.1 - 0.00013 21.9 0.0 0.0075 16.1 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EMR65368.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain FliT PF05400.8 EMR65369.1 - 0.86 10.0 15.1 0.13 12.7 3.1 3.4 3 0 0 3 3 3 0 Flagellar protein FliT AATF-Che1 PF13339.1 EMR65369.1 - 2.5 8.2 10.5 1.9 8.6 3.4 2.4 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Sedlin_N PF04628.8 EMR65370.1 - 8.2e-40 135.7 0.0 9.4e-40 135.5 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EMR65370.1 - 0.00049 19.8 0.0 0.0081 15.8 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family Isy1 PF06246.7 EMR65372.1 - 1.2e-88 296.8 0.8 1.4e-88 296.6 0.5 1.0 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 EMR65372.1 - 0.007 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 YolD-like protein Metallophos PF00149.23 EMR65373.1 - 0.00087 18.7 0.2 0.0023 17.3 0.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.11 EMR65374.1 - 1.4e-20 73.2 55.2 6e-10 38.3 21.7 3.5 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 EMR65374.1 - 3.3e-08 32.2 23.0 4.3e-08 31.8 16.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Amidase PF01425.16 EMR65375.1 - 5.5e-83 279.2 0.0 6.8e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF2760 PF10816.3 EMR65375.1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) Beach PF02138.13 EMR65376.1 - 5.5e-82 275.2 0.0 7.6e-82 274.7 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EMR65376.1 - 6.9e-09 35.2 7.0 0.023 14.5 0.2 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-rbx1 PF12678.2 EMR65377.1 - 0.085 12.9 6.7 3.1 7.9 4.7 2.5 1 1 0 1 1 1 0 RING-H2 zinc finger DUF766 PF05571.7 EMR65377.1 - 0.18 11.0 1.2 0.29 10.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF766) zf-RING_2 PF13639.1 EMR65377.1 - 0.22 11.3 10.1 0.48 10.2 7.0 1.6 1 0 0 1 1 1 0 Ring finger domain RINGv PF12906.2 EMR65377.1 - 1.2 9.2 9.4 5 7.2 6.6 2.0 1 1 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 EMR65377.1 - 1.5 8.5 8.3 1.4 8.6 4.2 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UQ_con PF00179.21 EMR65379.1 - 3.1e-46 156.2 0.0 3.5e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMR65379.1 - 0.00036 20.2 0.0 0.00048 19.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMR65379.1 - 0.03 14.1 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 EMR65379.1 - 0.071 12.7 0.1 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 UEV domain PRP38 PF03371.10 EMR65380.1 - 5.1e-62 208.5 0.0 6.3e-62 208.2 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.2 EMR65380.1 - 0.038 14.5 32.1 0.076 13.5 22.3 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Peptidase_S8 PF00082.17 EMR65381.1 - 2.5e-49 167.9 7.0 4e-49 167.2 4.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMR65381.1 - 1.1e-21 77.2 0.2 2.8e-21 75.8 0.1 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1450 PF07293.6 EMR65381.1 - 0.091 12.7 0.2 2.2 8.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) Phasin PF05597.6 EMR65381.1 - 0.097 12.4 0.5 0.18 11.5 0.4 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) NmrA PF05368.8 EMR65382.1 - 2.1e-34 118.8 0.1 4.2e-34 117.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR65382.1 - 1e-14 54.9 1.5 1.9e-14 54.0 1.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR65382.1 - 1.8e-06 27.5 0.0 8.3e-06 25.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EMR65382.1 - 0.00056 19.6 0.4 0.00096 18.8 0.3 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EMR65382.1 - 0.0041 15.8 0.0 0.0073 15.0 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMR65382.1 - 0.011 15.6 0.8 0.02 14.8 0.6 1.5 1 0 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.12 EMR65382.1 - 0.11 12.9 0.3 0.31 11.4 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SIP1 PF04938.7 EMR65383.1 - 1.9e-06 27.4 0.2 0.039 13.2 0.0 3.2 3 0 0 3 3 3 3 Survival motor neuron (SMN) interacting protein 1 (SIP1) Pyridoxal_deC PF00282.14 EMR65384.1 - 4.3e-60 203.1 0.0 5.8e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EMR65384.1 - 0.00019 20.3 0.0 0.00039 19.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V WD40 PF00400.27 EMR65385.1 - 1.5e-10 40.5 18.7 3.8e-05 23.3 0.4 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat RWD PF05773.17 EMR65385.1 - 0.00091 19.1 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 EMR65385.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme ADH_zinc_N PF00107.21 EMR65386.1 - 7.9e-15 54.5 0.1 1.5e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACC_epsilon PF13822.1 EMR65386.1 - 0.059 13.7 0.2 0.059 13.7 0.1 2.3 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit DDOST_48kD PF03345.9 EMR65387.1 - 8.5e-170 564.8 0.0 9.5e-170 564.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta WD40 PF00400.27 EMR65388.1 - 3.6e-16 58.3 1.6 0.16 11.8 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat SAPS PF04499.10 EMR65388.1 - 0.096 11.3 2.6 0.12 10.9 1.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 EMR65388.1 - 0.32 8.9 17.9 0.71 7.8 11.9 1.7 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 EMR65388.1 - 0.5 8.2 24.2 0.64 7.8 16.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 EMR65388.1 - 8.3 5.7 20.5 13 5.0 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1680 PF07944.7 EMR65389.1 - 0.00048 18.5 0.1 0.00051 18.4 0.1 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) CBM_11 PF03425.8 EMR65389.1 - 0.078 12.6 0.0 0.083 12.5 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) Oxidored_FMN PF00724.15 EMR65390.1 - 1.7e-100 336.3 0.0 2e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ank_2 PF12796.2 EMR65391.1 - 3.9e-59 196.9 23.7 6.2e-12 45.6 0.1 6.1 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EMR65391.1 - 1.7e-39 131.6 19.1 9.6e-05 22.0 0.1 10.8 10 0 0 10 10 10 10 Ankyrin repeat Ank_4 PF13637.1 EMR65391.1 - 1.3e-35 121.1 19.5 4.9e-07 30.1 0.7 9.7 4 2 5 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR65391.1 - 5.3e-33 109.7 11.6 0.00019 21.3 0.0 11.3 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.1 EMR65391.1 - 1.8e-30 104.2 12.9 5.2e-09 36.0 0.0 8.6 5 3 4 9 9 9 7 Ankyrin repeats (many copies) zf-C2H2_4 PF13894.1 EMR65392.1 - 0.0021 18.2 9.4 0.0033 17.6 0.2 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EMR65392.1 - 0.0036 17.5 13.6 0.024 14.9 0.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type Tombus_P33 PF08500.5 EMR65392.1 - 0.055 13.2 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Tombusvirus p33 zf-RING_UBOX PF13445.1 EMR65392.1 - 0.13 12.0 0.7 0.25 11.1 0.1 1.8 2 0 0 2 2 2 0 RING-type zinc-finger UPF0547 PF10571.4 EMR65392.1 - 0.97 9.1 7.4 1.7 8.3 0.4 2.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Acyl_transf_3 PF01757.17 EMR65393.1 - 3.2e-28 98.5 26.9 4.1e-28 98.2 18.7 1.1 1 0 0 1 1 1 1 Acyltransferase family EF-hand_1 PF00036.27 EMR65394.1 - 0.05 12.9 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 EF hand DUF4116 PF13475.1 EMR65394.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Glyco_transf_54 PF04666.8 EMR65395.1 - 6.9e-11 41.4 0.0 8.2e-10 37.8 0.0 2.3 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region zf-RING_2 PF13639.1 EMR65396.1 - 7e-10 38.5 5.4 7e-10 38.5 3.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 EMR65396.1 - 1e-05 25.2 2.0 1e-05 25.2 1.4 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 EMR65396.1 - 3.5e-05 23.4 6.7 0.0026 17.4 1.4 2.5 1 1 1 2 2 2 2 Prokaryotic RING finger family 1 zf-RING_5 PF14634.1 EMR65396.1 - 5.2e-05 22.8 5.5 5.2e-05 22.8 3.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EMR65396.1 - 0.00015 21.8 2.7 0.00015 21.8 1.9 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger FANCL_C PF11793.3 EMR65396.1 - 0.00031 20.6 3.6 0.00031 20.6 2.5 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain PHD PF00628.24 EMR65396.1 - 0.00067 19.3 6.6 0.0014 18.2 4.5 1.6 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_2 PF13923.1 EMR65396.1 - 0.0012 18.8 5.7 0.0012 18.8 3.9 2.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) SWIM PF04434.12 EMR65396.1 - 0.0012 18.2 1.2 0.0023 17.3 0.9 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-C3HC4_3 PF13920.1 EMR65396.1 - 0.002 17.7 3.5 0.002 17.7 2.4 2.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMR65396.1 - 0.017 14.7 6.0 0.017 14.7 4.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EMR65396.1 - 0.028 14.3 4.2 0.069 13.0 2.9 1.6 1 0 0 1 1 1 0 FYVE zinc finger RINGv PF12906.2 EMR65396.1 - 0.086 12.8 5.6 0.23 11.5 3.9 1.8 1 0 0 1 1 1 0 RING-variant domain zf-Di19 PF05605.7 EMR65396.1 - 0.15 12.2 0.2 0.15 12.2 0.2 3.0 3 1 1 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding Ndc1_Nup PF09531.5 EMR65396.1 - 0.18 10.1 1.8 0.18 10.1 1.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-RING_4 PF14570.1 EMR65396.1 - 0.26 10.9 12.0 0.065 12.8 5.7 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3987 PF13148.1 EMR65396.1 - 0.26 9.8 4.2 0.41 9.1 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Ferritin_2 PF13668.1 EMR65397.1 - 3.4e-15 56.2 0.0 5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Polysacc_synt_C PF14667.1 EMR65398.1 - 0.0046 16.7 2.3 0.0069 16.1 1.5 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain DUF2975 PF11188.3 EMR65398.1 - 0.087 12.5 2.8 0.12 12.0 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) PepSY_TM_2 PF13703.1 EMR65398.1 - 3.1 8.0 8.6 7.9 6.7 1.2 2.1 1 1 1 2 2 2 0 PepSY-associated TM helix RRM_5 PF13893.1 EMR65399.1 - 0.0088 15.8 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GFO_IDH_MocA PF01408.17 EMR65400.1 - 6.2e-28 97.7 0.2 9.2e-28 97.1 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMR65400.1 - 1.3e-13 50.7 0.0 2.5e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EMR65400.1 - 0.00069 19.9 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 EMR65400.1 - 0.0087 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EMR65400.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CoA_binding_2 PF13380.1 EMR65400.1 - 0.11 12.6 0.1 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain OCD_Mu_crystall PF02423.10 EMR65400.1 - 0.14 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Shikimate_dh_N PF08501.6 EMR65401.1 - 7.4e-22 77.2 0.0 1.2e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EMR65401.1 - 1.8e-10 41.0 0.0 2.9e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DHquinase_I PF01487.10 EMR65402.1 - 2e-40 138.8 0.0 3.7e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 EMR65402.1 - 3.6e-20 71.7 0.0 9.9e-20 70.3 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EMR65402.1 - 1.6e-11 44.4 0.0 3.6e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SKI PF01202.17 EMR65402.1 - 1.3e-10 41.3 0.1 3.1e-10 40.1 0.1 1.7 2 0 0 2 2 2 1 Shikimate kinase F420_oxidored PF03807.12 EMR65402.1 - 0.0026 18.1 0.0 0.0059 17.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EMR65402.1 - 0.22 10.4 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DHquinase_II PF01220.14 EMR65403.1 - 1.2e-59 199.6 0.1 1.3e-59 199.5 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Peroxidase_2 PF01328.12 EMR65404.1 - 8.4e-45 152.8 0.3 1.1e-44 152.4 0.2 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 AP_endonuc_2 PF01261.19 EMR65405.1 - 1.5e-27 96.3 0.0 2.1e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Sugar_tr PF00083.19 EMR65406.1 - 8.2e-130 433.3 22.8 9.3e-130 433.1 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR65406.1 - 1.9e-26 92.6 36.2 1.9e-26 92.6 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YebO PF13974.1 EMR65406.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 YebO-like protein CorA PF01544.13 EMR65406.1 - 2.5 7.0 6.5 14 4.5 0.1 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein adh_short PF00106.20 EMR65407.1 - 9.9e-08 32.0 0.0 1.2e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR65407.1 - 0.018 14.7 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.1 EMR65407.1 - 0.02 14.6 0.0 0.026 14.3 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Pyr_redox PF00070.22 EMR65407.1 - 0.083 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_43 PF04616.9 EMR65408.1 - 5.8e-33 114.1 5.9 8.2e-33 113.7 4.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Phage_min_tail PF05939.8 EMR65408.1 - 0.081 12.8 0.1 11 6.0 0.0 2.7 3 0 0 3 3 3 0 Phage minor tail protein Lactamase_B PF00753.22 EMR65411.1 - 3.6e-11 43.0 1.1 5.6e-11 42.4 0.8 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMR65411.1 - 0.0014 18.1 0.2 0.0025 17.3 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain AMP-binding PF00501.23 EMR65412.1 - 1.3e-85 287.3 0.0 1.7e-85 286.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMR65412.1 - 8.4e-14 52.2 3.1 2.4e-13 50.8 0.5 2.9 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain TPR_10 PF13374.1 EMR65413.1 - 0.015 15.1 1.2 3.9 7.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 EMR65413.1 - 0.051 13.6 2.0 5.7 7.1 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ACC_epsilon PF13822.1 EMR65413.1 - 0.068 13.5 0.3 0.068 13.5 0.2 2.9 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit TPR_16 PF13432.1 EMR65413.1 - 2.3 9.0 11.4 7.1 7.4 1.6 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3246 PF11596.3 EMR65414.1 - 0.00043 19.6 2.4 0.0006 19.1 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) MSP1_C PF07462.6 EMR65414.1 - 0.34 9.2 2.0 0.46 8.8 1.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Arb2 PF09757.4 EMR65415.1 - 2.7e-21 75.8 0.0 5e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Arb2 domain Prok-E2_D PF14460.1 EMR65415.1 - 0.00044 19.7 0.0 0.00067 19.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family D 2OG-FeII_Oxy_2 PF13532.1 EMR65416.1 - 6.8e-20 71.7 0.0 1.3e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMR65416.1 - 0.0029 17.8 0.0 0.0061 16.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4191 PF13829.1 EMR65418.1 - 0.017 14.2 0.5 0.017 14.2 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF1469 PF07332.6 EMR65418.1 - 2.6 7.8 11.1 1.9 8.2 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Ribosomal_S14 PF00253.16 EMR65419.1 - 9e-16 56.9 1.3 1.1e-15 56.7 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e RRM_1 PF00076.17 EMR65419.1 - 0.026 14.1 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tet_JBP PF12851.2 EMR65420.1 - 1.1e-06 28.1 0.0 2.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Amino_oxidase PF01593.19 EMR65421.1 - 1e-34 120.4 0.1 9.6e-28 97.4 0.2 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMR65421.1 - 2.7e-06 27.3 0.0 5.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain RAI16-like PF10257.4 EMR65421.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein FAD_binding_3 PF01494.14 EMR65421.1 - 0.16 10.9 0.4 0.46 9.4 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain MIP PF00230.15 EMR65422.1 - 5.4e-41 140.5 5.4 6.9e-41 140.1 3.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein TauE PF01925.14 EMR65422.1 - 5.3 6.4 11.3 0.39 10.1 4.1 1.8 2 1 0 2 2 2 0 Sulfite exporter TauE/SafE 3Beta_HSD PF01073.14 EMR65423.1 - 3.1e-18 65.4 0.0 4.4e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMR65423.1 - 1.8e-17 63.6 0.0 2.5e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR65423.1 - 9.4e-15 55.0 0.0 1.5e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMR65423.1 - 2.9e-09 36.2 0.0 1.8e-08 33.6 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EMR65423.1 - 4.4e-07 29.9 0.0 1.1e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EMR65423.1 - 1.1e-05 24.8 0.0 2.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EMR65423.1 - 0.00056 18.9 0.0 0.0014 17.5 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EMR65423.1 - 0.0035 17.0 0.0 0.011 15.4 0.0 1.7 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EMR65423.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase RRM_1 PF00076.17 EMR65424.1 - 4e-82 269.8 4.1 1.3e-20 72.7 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR65424.1 - 2.8e-54 180.9 1.0 4.5e-14 52.1 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR65424.1 - 2.6e-40 136.0 0.0 2e-09 37.1 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EMR65424.1 - 5.1e-29 99.7 2.0 2.1e-28 97.7 1.2 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EMR65424.1 - 0.00055 19.6 0.2 2.8 7.7 0.0 4.4 4 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Nab6_mRNP_bdg PF10567.4 EMR65424.1 - 0.0038 16.2 0.8 0.014 14.3 0.3 2.0 2 0 0 2 2 2 1 RNA-recognition motif Limkain-b1 PF11608.3 EMR65424.1 - 0.023 14.4 3.3 12 5.7 0.0 4.0 4 0 0 4 4 4 0 Limkain b1 CbiG_mid PF11761.3 EMR65424.1 - 0.023 14.9 0.1 4.2 7.6 0.0 3.6 3 0 0 3 3 3 0 Cobalamin biosynthesis central region OB_RNB PF08206.6 EMR65424.1 - 0.052 13.0 1.7 8.2 6.0 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain p450 PF00067.17 EMR65425.1 - 9.9e-32 110.0 0.0 1.5e-27 96.2 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Flu_M2 PF00599.12 EMR65425.1 - 0.049 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M2) BLVR PF06375.6 EMR65425.1 - 0.36 10.6 8.2 0.59 9.9 5.7 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) NST1 PF13945.1 EMR65425.1 - 0.42 10.6 6.9 0.69 9.9 4.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator XFP_N PF09364.5 EMR65426.1 - 0.065 11.7 0.0 0.26 9.8 0.0 1.8 2 0 0 2 2 2 0 XFP N-terminal domain Baculo_PEP_C PF04513.7 EMR65426.1 - 0.14 11.9 0.0 0.54 10.0 0.0 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Usp PF00582.21 EMR65427.1 - 3.2e-15 56.5 0.1 1.7e-14 54.2 0.0 2.1 2 0 0 2 2 2 1 Universal stress protein family HECT PF00632.20 EMR65428.1 - 6.1e-82 275.2 0.0 7.7e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Mucin PF01456.12 EMR65429.1 - 0.92 9.2 25.5 0.2 11.4 14.7 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein Med3 PF11593.3 EMR65429.1 - 1.7 7.7 13.0 2.3 7.3 9.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TrkH PF02386.11 EMR65431.1 - 9.9e-86 287.4 0.0 1.5e-85 286.8 0.0 1.3 1 0 0 1 1 1 1 Cation transport protein F-box-like PF12937.2 EMR65432.1 - 0.0076 15.9 0.3 0.019 14.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like Chitin_bind_3 PF03067.10 EMR65433.1 - 0.00063 20.0 0.0 0.00079 19.7 0.0 1.3 1 0 0 1 1 1 1 Chitin binding domain Dus PF01207.12 EMR65435.1 - 1.7e-34 119.0 0.0 1.1e-25 90.1 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EMR65435.1 - 0.039 13.6 7.3 1.7 8.4 0.8 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4576 PF15144.1 EMR65435.1 - 2.6 7.7 4.0 0.88 9.2 0.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4576) zf-met2 PF12907.2 EMR65436.1 - 0.00031 20.6 1.9 0.00053 19.9 1.3 1.4 1 0 0 1 1 1 1 Zinc-binding DUF1479 PF07350.7 EMR65437.1 - 3.9e-144 480.2 0.0 1.1e-142 475.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.8 EMR65437.1 - 0.014 15.4 2.0 0.59 10.1 0.1 3.0 4 0 0 4 4 4 0 Phytanoyl-CoA dioxygenase (PhyH) HHH PF00633.18 EMR65437.1 - 0.02 14.5 0.1 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Kelch_4 PF13418.1 EMR65438.1 - 2.8e-23 81.4 7.5 7.7e-06 25.5 0.0 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 EMR65438.1 - 6.1e-21 73.7 0.5 7.3e-05 22.2 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 EMR65438.1 - 2.1e-20 71.9 2.8 0.00046 20.2 0.1 4.7 2 1 2 4 4 4 4 Kelch motif Kelch_5 PF13854.1 EMR65438.1 - 9e-20 70.2 3.7 3.7e-06 26.7 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.10 EMR65438.1 - 1.5e-18 65.7 3.8 3.8e-05 23.2 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 EMR65438.1 - 4.6e-17 61.6 2.5 2.6e-07 30.6 0.0 4.9 4 0 0 4 4 4 3 Galactose oxidase, central domain BTB PF00651.26 EMR65438.1 - 5.6e-10 39.1 0.1 9.7e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 EMR65438.1 - 0.0074 16.1 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Rax2 PF12768.2 EMR65438.1 - 0.1 11.7 0.0 0.55 9.3 0.0 2.2 2 1 1 3 3 3 0 Cortical protein marker for cell polarity Tannase PF07519.6 EMR65439.1 - 7.3e-68 229.3 0.0 1.2e-65 222.1 0.0 2.2 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EMR65439.1 - 0.00025 21.0 0.0 0.00069 19.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR65439.1 - 0.00061 19.0 0.0 0.56 9.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EMR65439.1 - 0.0011 18.5 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR65439.1 - 0.0019 17.9 0.0 0.033 13.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Kelch_4 PF13418.1 EMR65440.1 - 8.3e-45 150.3 18.7 4.8e-12 45.4 0.1 6.8 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EMR65440.1 - 2.7e-40 135.6 12.5 1.5e-07 31.2 0.0 6.9 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EMR65440.1 - 6.4e-36 121.6 11.8 5.3e-09 35.4 0.4 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EMR65440.1 - 2e-32 109.9 15.1 9.1e-09 35.1 0.1 6.6 4 2 2 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EMR65440.1 - 2e-30 103.3 13.1 1.4e-08 34.1 0.1 6.9 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 EMR65440.1 - 2.9e-30 103.6 49.6 6.3e-10 38.9 0.1 9.5 9 2 0 9 9 9 6 Galactose oxidase, central domain MIP-T3 PF10243.4 EMR65440.1 - 1.9 6.8 28.4 0.0096 14.4 13.8 1.4 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 ADH_N PF08240.7 EMR65441.1 - 2.5e-26 91.5 3.7 2.5e-26 91.5 2.6 2.0 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR65441.1 - 2e-15 56.4 0.0 3.8e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 EMR65441.1 - 0.016 14.8 0.3 0.25 11.1 0.0 2.5 1 1 1 2 2 2 0 S1-like DIOX_N PF14226.1 EMR65442.1 - 2.5e-30 105.3 0.0 2e-29 102.4 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMR65442.1 - 1.2e-14 54.3 0.0 2.4e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 EMR65443.1 - 5.4e-24 83.1 16.9 1.7e-06 27.6 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EMR65443.1 - 7.3e-06 25.8 0.5 0.00033 20.4 0.1 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EMR65443.1 - 0.053 13.0 0.0 0.56 9.7 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain HIG_1_N PF04588.8 EMR65444.1 - 2.2e-08 33.6 1.6 6e-08 32.3 1.1 1.8 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Bap31 PF05529.7 EMR65445.1 - 6.6e-60 201.8 4.6 8.1e-60 201.5 3.2 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Filament PF00038.16 EMR65445.1 - 0.0075 15.7 1.0 0.011 15.2 0.7 1.2 1 0 0 1 1 1 1 Intermediate filament protein She9_MDM33 PF05546.6 EMR65445.1 - 0.1 12.1 0.6 0.21 11.1 0.4 1.5 1 0 0 1 1 1 0 She9 / Mdm33 family ATG2_CAD PF13329.1 EMR65449.1 - 6.3e-51 172.0 0.5 1.4e-50 170.8 0.1 1.8 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EMR65449.1 - 7e-30 103.0 0.2 1.8e-29 101.7 0.1 1.7 1 0 0 1 1 1 1 ATG C terminal domain YibE_F PF07907.6 EMR65449.1 - 0.22 10.6 0.2 0.34 10.0 0.1 1.2 1 0 0 1 1 1 0 YibE/F-like protein Glyco_hydro_43 PF04616.9 EMR65451.1 - 3.1e-69 233.2 0.7 4.1e-69 232.8 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Chorein_N PF12624.2 EMR65452.1 - 0.02 14.4 1.2 0.029 13.8 0.1 1.8 2 0 0 2 2 2 0 N-terminal region of Chorein, a TM vesicle-mediated sorter zf-C2H2_4 PF13894.1 EMR65453.1 - 0.00045 20.3 14.7 1.2 9.5 0.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger HALZ PF02183.13 EMR65453.1 - 0.00067 19.3 1.2 0.0013 18.4 0.0 2.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper GAS PF13851.1 EMR65453.1 - 0.0073 15.5 1.1 0.012 14.8 0.8 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Rootletin PF15035.1 EMR65453.1 - 0.029 14.3 4.4 0.057 13.3 3.1 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion zf-C2H2 PF00096.21 EMR65453.1 - 0.11 12.9 15.3 0.81 10.1 1.9 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type FadA PF09403.5 EMR65453.1 - 0.12 12.4 0.3 0.22 11.5 0.2 1.4 1 0 0 1 1 1 0 Adhesion protein FadA DUF904 PF06005.7 EMR65453.1 - 0.12 12.6 1.8 0.27 11.5 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF4259 PF14078.1 EMR65453.1 - 0.18 12.3 0.2 0.38 11.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Macoilin PF09726.4 EMR65453.1 - 0.3 9.3 3.0 0.28 9.4 1.0 1.6 2 0 0 2 2 2 0 Transmembrane protein IncA PF04156.9 EMR65453.1 - 1.1 8.8 3.0 1.7 8.1 2.1 1.2 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 EMR65455.1 - 1.3e-23 81.9 17.8 5.6e-09 35.5 0.3 6.2 5 1 1 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 EMR65455.1 - 0.00054 18.2 0.6 0.65 8.0 0.0 3.4 3 1 0 4 4 4 3 Nucleoporin Nup120/160 Kinetocho_Slk19 PF12709.2 EMR65456.1 - 2.6e-21 75.4 0.5 2.6e-21 75.4 0.4 5.3 6 0 0 6 6 6 2 Central kinetochore-associated Spt20 PF12090.3 EMR65456.1 - 0.19 11.0 12.7 0.23 10.7 3.3 2.4 2 0 0 2 2 2 0 Spt20 family LpxB PF02684.10 EMR65456.1 - 0.34 9.5 6.6 2.1 6.9 1.1 2.4 2 0 0 2 2 2 0 Lipid-A-disaccharide synthetase Eapp_C PF10238.4 EMR65456.1 - 5.2 6.9 15.5 7.9 6.3 1.0 3.3 3 0 0 3 3 3 0 E2F-associated phosphoprotein Acyl-CoA_dh_1 PF00441.19 EMR65457.1 - 3.6e-34 118.0 0.3 5.7e-34 117.3 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EMR65457.1 - 7.7e-19 67.2 0.0 1.8e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EMR65457.1 - 7.7e-17 60.5 0.5 1.7e-16 59.4 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EMR65457.1 - 1.5e-06 28.7 0.3 7.5e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMR65457.1 - 0.0044 17.2 0.0 0.013 15.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_S20p PF01649.13 EMR65457.1 - 0.11 12.8 0.1 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S20 AA_permease PF00324.16 EMR65458.1 - 7.1e-100 334.6 46.6 2.7e-99 332.6 32.3 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR65458.1 - 6.1e-25 87.6 44.1 8.5e-25 87.1 30.5 1.1 1 0 0 1 1 1 1 Amino acid permease Cellulase PF00150.13 EMR65458.1 - 2.9e-17 62.7 0.0 6.8e-12 45.1 0.0 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 EMR65458.1 - 0.00055 19.3 0.1 0.0011 18.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 Peroxidase_2 PF01328.12 EMR65459.1 - 4.6e-32 110.9 0.3 1.3e-31 109.5 0.2 1.7 1 1 0 1 1 1 1 Peroxidase, family 2 PS_Dcarbxylase PF02666.10 EMR65460.1 - 4.9e-53 179.4 0.0 7.4e-53 178.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EMR65460.1 - 1.2e-33 114.8 0.0 2.1e-16 59.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 EMR65460.1 - 0.0054 16.8 0.1 0.014 15.4 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EMR65460.1 - 0.0096 15.7 0.5 0.033 14.0 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain CEP76-C2 PF15627.1 EMR65460.1 - 0.032 13.7 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 CEP76 C2 domain EF-hand_1 PF00036.27 EMR65460.1 - 0.045 13.0 0.3 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 EF hand ADIP PF11559.3 EMR65461.1 - 5.6e-14 52.3 10.5 8.7e-10 38.6 0.2 4.9 4 1 1 5 5 5 2 Afadin- and alpha -actinin-Binding DUF2365 PF10157.4 EMR65461.1 - 0.023 14.5 0.0 0.072 12.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) AFG1_ATPase PF03969.11 EMR65462.1 - 4.2e-55 187.0 0.1 6.7e-26 90.9 0.0 5.1 4 1 1 5 5 5 5 AFG1-like ATPase AAA_16 PF13191.1 EMR65462.1 - 2.5e-05 24.3 0.2 0.006 16.5 0.0 2.9 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EMR65462.1 - 0.0011 18.5 0.1 0.11 12.1 0.0 2.7 2 1 0 2 2 2 1 NACHT domain AAA_5 PF07728.9 EMR65462.1 - 0.0012 18.5 0.0 0.0049 16.6 0.0 2.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMR65462.1 - 0.017 15.2 0.0 0.079 13.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMR65462.1 - 0.047 13.9 0.3 7.9 6.7 0.0 2.6 1 1 1 2 2 2 0 ABC transporter AAA PF00004.24 EMR65462.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 EMR65462.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase KAP_NTPase PF07693.9 EMR65462.1 - 0.12 11.3 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.1 EMR65462.1 - 0.12 11.9 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Bac_DnaA PF00308.13 EMR65462.1 - 0.18 11.4 0.0 1.3 8.6 0.0 2.2 2 1 0 2 2 2 0 Bacterial dnaA protein DUF952 PF06108.7 EMR65463.1 - 7.8e-20 70.5 0.0 9.7e-20 70.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Pkinase PF00069.20 EMR65464.1 - 3.3e-25 88.7 0.0 5.5e-24 84.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR65464.1 - 8.4e-11 41.4 0.0 4.2e-10 39.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase WW PF00397.21 EMR65464.1 - 0.0025 17.6 4.2 0.0096 15.7 0.1 3.1 3 0 0 3 3 3 1 WW domain Amino_oxidase PF01593.19 EMR65465.1 - 5.6e-12 45.4 1.8 4e-06 26.1 0.9 2.3 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EMR65465.1 - 0.099 12.4 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Peptidase_M64 PF09471.5 EMR65466.1 - 0.04 13.5 1.7 0.12 11.9 0.2 1.9 2 0 0 2 2 2 0 IgA Peptidase M64 MFS_1 PF07690.11 EMR65467.1 - 1e-16 60.6 18.2 1e-15 57.3 12.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EMR65467.1 - 2.5 8.5 0.0 2.5 8.5 0.0 3.2 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) IDO PF01231.13 EMR65468.1 - 6.7e-35 120.3 0.0 2.3e-34 118.5 0.0 1.7 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase zf-AN1 PF01428.11 EMR65469.1 - 6.6e-11 41.9 11.6 9.5e-11 41.4 8.0 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger p450 PF00067.17 EMR65470.1 - 5.7e-66 222.9 0.0 7.2e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.12 EMR65470.1 - 0.03 13.9 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 Reticulon DUF1970 PF09301.5 EMR65470.1 - 0.038 14.0 0.0 0.96 9.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) CP_ATPgrasp_1 PF04174.8 EMR65471.1 - 7.6e-78 261.4 0.0 1.1e-77 260.8 0.0 1.3 1 0 0 1 1 1 1 A circularly permuted ATPgrasp GCS2 PF04107.8 EMR65471.1 - 1.9e-43 148.6 0.2 3e-43 148.0 0.1 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) CP_ATPgrasp_2 PF14403.1 EMR65471.1 - 3.1e-05 22.8 0.0 7.2e-05 21.6 0.0 1.6 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 ATP-grasp_4 PF13535.1 EMR65471.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Coatomer_E PF04733.9 EMR65472.1 - 4.2e-59 200.1 5.1 4.8e-59 199.9 3.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit Apc3 PF12895.2 EMR65472.1 - 6.3e-08 32.6 0.4 0.048 13.7 0.0 4.1 3 1 3 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EMR65472.1 - 5.1e-07 29.9 20.3 0.0031 17.8 1.7 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMR65472.1 - 1.1e-05 25.5 18.0 0.00096 19.5 0.3 6.4 6 2 2 8 8 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMR65472.1 - 1.2e-05 24.9 4.5 0.0011 18.5 0.0 4.4 4 2 1 5 5 5 1 TPR repeat TPR_16 PF13432.1 EMR65472.1 - 3.1e-05 24.5 13.3 0.0015 19.1 0.2 5.1 3 3 2 5 5 5 1 Tetratricopeptide repeat Type_III_YscG PF09477.5 EMR65472.1 - 3.8e-05 23.7 2.6 0.0011 18.9 0.1 3.2 1 1 0 2 2 2 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_1 PF00515.23 EMR65472.1 - 0.0001 21.7 0.6 1.3 8.7 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EMR65472.1 - 0.00015 20.9 2.8 0.16 10.9 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMR65472.1 - 0.00048 20.4 7.2 0.6 10.6 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMR65472.1 - 0.002 17.7 0.1 24 5.0 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMR65472.1 - 0.0029 17.6 1.0 3.5 8.0 0.0 4.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMR65472.1 - 0.0086 15.9 13.6 0.017 14.9 0.1 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat B12-binding PF02310.14 EMR65472.1 - 0.021 14.7 0.1 0.04 13.7 0.1 1.5 1 0 0 1 1 1 0 B12 binding domain TPR_12 PF13424.1 EMR65472.1 - 0.022 14.6 9.4 5.9 6.9 0.1 5.1 2 2 4 6 6 6 0 Tetratricopeptide repeat Arg_tRNA_synt_N PF03485.11 EMR65472.1 - 0.055 14.0 0.2 0.13 12.7 0.2 1.6 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain Apc5 PF12862.2 EMR65472.1 - 0.68 9.8 3.6 38 4.2 0.1 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_20 PF14561.1 EMR65472.1 - 0.73 9.9 5.2 5.1 7.2 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMR65472.1 - 1.2 9.0 6.9 6.6 6.6 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat ATP-synt_DE PF00401.15 EMR65472.1 - 2.2 8.2 8.8 3.7 7.5 0.7 3.1 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain TPR_4 PF07721.9 EMR65472.1 - 2.3 8.8 0.1 2.3 8.8 0.0 6.1 8 0 0 8 8 5 0 Tetratricopeptide repeat DUF3328 PF11807.3 EMR65473.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) HAD PF12710.2 EMR65475.1 - 5.4e-09 36.5 0.1 8.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR65475.1 - 0.0014 19.0 0.0 0.17 12.2 0.1 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EMR65475.1 - 0.0046 16.1 0.1 0.55 9.3 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase UMPH-1 PF05822.7 EMR65475.1 - 0.018 14.3 0.1 0.12 11.6 0.0 2.3 3 1 0 3 3 3 0 Pyrimidine 5'-nucleotidase (UMPH-1) Cut8_C PF08559.5 EMR65476.1 - 4.1e-46 156.3 0.0 5.4e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EMR65476.1 - 1.1e-15 57.1 0.7 2e-15 56.3 0.5 1.4 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 EMR65476.1 - 1.2e-07 31.5 1.4 2.2e-07 30.7 1.0 1.5 1 0 0 1 1 1 1 Cut8 proteasome-binding domain Nucleoporin_N PF08801.6 EMR65477.1 - 3.7e-77 259.8 0.2 5.1e-77 259.3 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 EMR65477.1 - 1.2e-73 248.6 16.6 1.9e-73 247.9 11.5 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Transcrip_act PF04949.8 EMR65477.1 - 0.062 12.9 3.1 0.24 11.0 0.0 2.9 3 0 0 3 3 3 0 Transcriptional activator DNA_pol_E_B PF04042.11 EMR65478.1 - 9.8e-55 185.0 0.0 1.5e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B BUD22 PF09073.5 EMR65478.1 - 0.08 12.0 7.7 0.13 11.2 5.3 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 EMR65478.1 - 0.22 9.5 4.3 0.44 8.5 3.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Cnd2 PF05786.9 EMR65478.1 - 0.47 8.8 8.2 0.75 8.2 5.7 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 Nop14 PF04147.7 EMR65478.1 - 0.59 7.9 8.1 0.86 7.4 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.10 EMR65478.1 - 0.8 8.2 3.4 1.3 7.5 2.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3439 PF11921.3 EMR65478.1 - 1.1 9.0 10.3 3.3 7.4 7.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TRAP_alpha PF03896.11 EMR65478.1 - 9.7 5.0 7.5 16 4.3 5.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Laminin_G_3 PF13385.1 EMR65479.1 - 1.5e-07 31.7 0.5 2.1e-07 31.3 0.4 1.4 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_16 PF00722.16 EMR65479.1 - 3e-05 23.3 0.2 4.7e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 VKOR PF07884.9 EMR65481.1 - 0.22 11.3 2.4 0.24 11.2 0.2 1.8 2 0 0 2 2 2 0 Vitamin K epoxide reductase family E1-E2_ATPase PF00122.15 EMR65482.1 - 1.6e-45 154.9 6.0 1.6e-45 154.9 4.2 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EMR65482.1 - 2.2e-24 87.0 0.2 3.8e-24 86.3 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMR65482.1 - 1.2e-12 48.3 0.0 2.4e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMR65482.1 - 7.7e-07 28.9 0.1 0.0021 17.6 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HMA PF00403.21 EMR65482.1 - 2e-05 24.6 0.1 5.6e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain S6PP PF05116.8 EMR65482.1 - 0.093 12.0 0.0 13 4.9 0.0 2.5 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase DUF3439 PF11921.3 EMR65482.1 - 1.2 8.8 12.0 0.17 11.6 2.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) KAR9 PF08580.5 EMR65483.1 - 8.4e-31 106.9 0.9 1e-30 106.7 0.7 1.0 1 0 0 1 1 1 1 Yeast cortical protein KAR9 SIS PF01380.17 EMR65484.1 - 3e-55 185.4 0.0 4.4e-30 103.9 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EMR65484.1 - 5.8e-28 97.6 0.0 9.5e-19 67.3 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMR65484.1 - 3.6e-19 69.0 0.0 8.7e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EMR65484.1 - 2.9e-11 43.1 0.0 9e-11 41.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EMR65484.1 - 2.2e-06 26.5 0.0 4.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Helicase_C PF00271.26 EMR65485.1 - 4.1e-18 64.9 0.0 1.4e-17 63.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RQC PF09382.5 EMR65485.1 - 4.9e-15 55.1 0.5 2.8e-14 52.7 0.1 2.2 2 0 0 2 2 2 1 RQC domain DEAD PF00270.24 EMR65485.1 - 3.2e-07 29.9 0.0 1.5e-05 24.5 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase HRDC PF00570.18 EMR65485.1 - 0.043 13.5 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 HRDC domain CpeT PF06206.6 EMR65487.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) AAA_16 PF13191.1 EMR65488.1 - 2.5e-15 56.9 0.1 1.9e-14 54.1 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMR65488.1 - 1.4e-12 47.8 0.0 3.4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMR65488.1 - 4.8e-11 42.9 0.0 1.2e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EMR65488.1 - 6.4e-05 22.7 0.0 0.00025 20.8 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EMR65488.1 - 0.00032 20.4 0.0 0.0006 19.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DUF815 PF05673.8 EMR65488.1 - 0.00057 18.8 0.0 0.001 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EMR65488.1 - 0.00082 19.5 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 EMR65488.1 - 0.00095 19.0 0.0 0.0022 17.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMR65488.1 - 0.0025 17.5 0.0 0.14 11.8 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 EMR65488.1 - 0.0033 16.1 0.0 0.0067 15.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EMR65488.1 - 0.0074 17.1 0.0 0.018 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EMR65488.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.17 EMR65488.1 - 0.014 14.2 0.0 0.042 12.7 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain PPV_E1_C PF00519.12 EMR65488.1 - 0.015 13.9 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_18 PF13238.1 EMR65488.1 - 0.017 15.4 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA12 PF10443.4 EMR65488.1 - 0.018 13.5 0.0 0.028 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein KAP_NTPase PF07693.9 EMR65488.1 - 0.022 13.7 0.0 0.069 12.1 0.0 1.7 1 1 1 2 2 2 0 KAP family P-loop domain AAA_30 PF13604.1 EMR65488.1 - 0.023 14.2 0.0 0.078 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EMR65488.1 - 0.034 13.7 0.0 0.051 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EMR65488.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 NTPase AAA_32 PF13654.1 EMR65488.1 - 0.053 12.1 0.0 0.081 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMR65488.1 - 0.062 13.0 0.0 0.15 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Miro PF08477.8 EMR65488.1 - 0.065 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein RuvB_N PF05496.7 EMR65488.1 - 0.073 12.1 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 EMR65488.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 EMR65488.1 - 0.18 10.5 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Proteasome PF00227.21 EMR65489.1 - 1.3e-24 86.4 0.0 7.2e-24 84.1 0.0 1.9 1 1 0 1 1 1 1 Proteasome subunit Peptidase_C97 PF05903.9 EMR65490.1 - 0.02 14.6 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 PPPDE putative peptidase domain DUF3716 PF12511.3 EMR65491.1 - 1.1e-13 50.6 2.9 1.8e-13 49.8 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) AAA PF00004.24 EMR65492.1 - 5e-43 146.4 0.0 8.8e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMR65492.1 - 7.4e-08 32.5 0.1 6.4e-06 26.2 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EMR65492.1 - 1.7e-06 27.8 0.1 3.7e-05 23.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMR65492.1 - 2.7e-06 27.5 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EMR65492.1 - 2.8e-06 27.3 0.0 7.7e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EMR65492.1 - 7.5e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EMR65492.1 - 0.00029 19.8 0.0 0.00058 18.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EMR65492.1 - 0.0003 20.4 0.0 0.00075 19.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EMR65492.1 - 0.00063 20.5 0.5 0.0023 18.7 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EMR65492.1 - 0.0011 19.2 0.1 0.0081 16.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMR65492.1 - 0.0013 18.5 0.0 0.0063 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EMR65492.1 - 0.0014 18.5 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EMR65492.1 - 0.0015 17.3 0.0 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EMR65492.1 - 0.0026 17.1 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EMR65492.1 - 0.003 16.7 0.0 0.0062 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF4200 PF13863.1 EMR65492.1 - 0.0045 16.9 1.4 0.0099 15.8 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) RNA_helicase PF00910.17 EMR65492.1 - 0.0051 16.9 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EMR65492.1 - 0.0055 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EMR65492.1 - 0.0074 15.7 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EMR65492.1 - 0.0091 15.4 0.1 0.047 13.0 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 EMR65492.1 - 0.0092 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EMR65492.1 - 0.018 14.9 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EMR65492.1 - 0.019 14.5 0.1 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMR65492.1 - 0.022 13.8 0.1 0.11 11.5 0.0 2.3 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.1 EMR65492.1 - 0.025 14.6 0.0 0.064 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Thymidylate_kin PF02223.12 EMR65492.1 - 0.026 13.8 0.0 1.4 8.2 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase ResIII PF04851.10 EMR65492.1 - 0.028 14.2 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 EMR65492.1 - 0.03 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 EMR65492.1 - 0.033 13.8 0.0 0.14 11.8 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase AAA_11 PF13086.1 EMR65492.1 - 0.039 13.5 0.3 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EMR65492.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EMR65492.1 - 0.051 13.2 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EMR65492.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EMR65492.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EMR65492.1 - 0.11 11.3 0.0 0.4 9.4 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain DAP3 PF10236.4 EMR65492.1 - 0.11 11.3 0.0 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_23 PF13476.1 EMR65492.1 - 2 8.6 6.6 3.4 7.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain HCNGP PF07818.8 EMR65493.1 - 8.4e-22 77.0 0.0 1.4e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 HCNGP-like protein Herpes_LMP2 PF07415.6 EMR65493.1 - 4.2 5.8 6.7 5.9 5.3 4.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein p450 PF00067.17 EMR65494.1 - 1.3e-59 201.9 0.0 1.8e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SIR2 PF02146.12 EMR65495.1 - 7.4e-45 152.8 0.0 1.3e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Sir2 family Lipoxygenase PF00305.14 EMR65495.1 - 5.7e-29 100.6 0.4 6.4e-23 80.6 0.0 3.0 1 1 1 2 2 2 2 Lipoxygenase Abhydrolase_3 PF07859.8 EMR65496.1 - 1.7e-51 174.7 1.2 2.7e-51 174.1 0.8 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMR65496.1 - 1.9e-09 36.8 0.2 4e-09 35.7 0.2 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EMR65496.1 - 0.00018 21.2 0.1 0.00023 20.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR65496.1 - 0.016 14.4 0.3 0.023 13.9 0.2 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EMR65496.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Fungal_trans PF04082.13 EMR65497.1 - 5.8e-13 48.3 0.0 1.5e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR65497.1 - 1.8e-05 24.5 11.9 2.9e-05 23.8 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Isochorismatase PF00857.15 EMR65498.1 - 4.3e-30 104.9 0.0 5.1e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.11 EMR65499.1 - 2.6e-39 134.9 21.6 5.3e-39 133.9 15.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR65499.1 - 7.8e-14 51.0 9.6 7.8e-14 51.0 6.7 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMR65499.1 - 1.4e-08 33.3 0.9 2.2e-08 32.8 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EMR65499.1 - 1.5e-05 23.6 0.6 1.5e-05 23.6 0.4 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 EMR65499.1 - 9.1e-05 20.7 0.4 0.00016 19.9 0.3 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.2 EMR65499.1 - 0.049 13.4 1.1 0.63 9.8 0.0 3.2 3 0 0 3 3 3 0 MFS_1 like family zf-Di19 PF05605.7 EMR65501.1 - 0.0025 17.8 0.1 0.17 12.0 0.1 2.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-RAG1 PF10426.4 EMR65501.1 - 0.045 13.7 0.8 0.19 11.6 0.1 2.2 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain zf-H2C2_5 PF13909.1 EMR65501.1 - 0.26 11.6 1.1 1.6 9.1 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF4448 PF14610.1 EMR65502.1 - 0.00033 20.1 0.0 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 EMR65502.1 - 0.0077 15.5 0.8 0.0077 15.5 0.6 2.5 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 EMR65502.1 - 0.054 13.0 1.3 0.084 12.4 0.0 2.0 2 0 0 2 2 2 0 Podoplanin ECH_C PF13766.1 EMR65502.1 - 0.077 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Glyco_trans_2_3 PF13632.1 EMR65503.1 - 2.3e-18 66.6 0.7 4.6e-18 65.6 0.5 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 HET PF06985.6 EMR65504.1 - 3.4e-13 49.9 2.3 9.9e-11 41.9 0.0 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF1543 PF07566.7 EMR65504.1 - 0.13 11.7 0.1 0.6 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1543) Aldedh PF00171.17 EMR65505.1 - 7e-136 453.2 0.9 8.4e-136 452.9 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family YtxC PF08812.6 EMR65505.1 - 0.031 13.8 0.3 0.061 12.8 0.0 1.5 2 0 0 2 2 2 0 YtxC-like family adh_short_C2 PF13561.1 EMR65506.1 - 2.2e-25 89.8 0.0 3.1e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR65506.1 - 1.6e-21 76.9 6.9 2.5e-21 76.3 4.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR65506.1 - 5.6e-12 45.6 1.2 9.8e-12 44.9 0.8 1.5 1 0 0 1 1 1 1 KR domain ADH_N PF08240.7 EMR65507.1 - 4.6e-29 100.3 1.4 6.1e-29 99.9 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR65507.1 - 2.8e-22 78.6 0.2 2.8e-22 78.6 0.2 1.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR65507.1 - 4.3e-05 24.3 0.2 0.0001 23.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMR65507.1 - 0.011 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 EMR65507.1 - 0.016 13.7 0.9 0.023 13.1 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein AdoHcyase_NAD PF00670.16 EMR65507.1 - 0.017 14.9 0.9 0.034 13.9 0.6 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EMR65507.1 - 0.022 14.1 0.1 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 EMR65507.1 - 0.024 15.1 0.0 0.045 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.16 EMR65507.1 - 0.036 13.6 0.6 0.059 12.9 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EMR65507.1 - 0.043 14.2 0.8 0.28 11.5 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR65507.1 - 0.35 10.7 2.2 0.92 9.3 1.6 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_2_N PF02837.13 EMR65508.1 - 2.9e-12 46.4 0.4 8.4e-12 44.9 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EMR65508.1 - 6.7e-11 42.6 0.1 2.3e-10 40.9 0.1 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EMR65508.1 - 0.023 13.6 0.1 0.039 12.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain HET PF06985.6 EMR65510.1 - 1.8e-23 83.2 0.2 3.4e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3136 PF11334.3 EMR65510.1 - 0.051 12.9 0.1 0.14 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Amidohydro_2 PF04909.9 EMR65511.1 - 4.3e-35 121.6 0.3 5e-35 121.3 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase FAD_binding_4 PF01565.18 EMR65512.1 - 1.1e-16 60.5 0.5 1.9e-16 59.7 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 EMR65513.1 - 8.3e-40 136.5 26.6 1.3e-39 135.9 18.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PgaD PF13994.1 EMR65513.1 - 0.087 12.3 0.8 0.42 10.0 0.0 2.6 3 0 0 3 3 3 0 PgaD-like protein Glyco_transf_90 PF05686.7 EMR65514.1 - 1.8e-05 23.6 0.1 0.00047 18.9 0.1 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 90 Pkinase PF00069.20 EMR65515.1 - 1.4e-63 214.4 0.0 3.9e-63 213.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR65515.1 - 1.7e-36 125.6 0.0 4.7e-31 107.7 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMR65515.1 - 1.7e-06 27.2 0.0 0.0041 16.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EMR65515.1 - 0.0031 17.2 0.0 0.0068 16.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EMR65515.1 - 0.0061 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EMR65515.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMR65515.1 - 0.088 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Methyltrans_SAM PF10672.4 EMR65516.1 - 0.12 11.1 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase p450 PF00067.17 EMR65517.1 - 3.6e-42 144.4 0.0 5.6e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ras PF00071.17 EMR65517.1 - 2.2e-31 108.4 0.0 3.7e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR65517.1 - 1.5e-08 35.1 0.0 2.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMR65517.1 - 1.1e-05 24.7 0.0 3.8e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMR65517.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DEAD PF00270.24 EMR65519.1 - 1e-26 93.4 0.1 5.1e-26 91.1 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR65519.1 - 5.7e-24 83.7 0.1 2.3e-23 81.8 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR65519.1 - 0.0004 20.2 0.0 0.00087 19.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PRK PF00485.13 EMR65520.1 - 2.5e-05 23.9 0.2 0.0039 16.7 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 EMR65520.1 - 0.091 13.0 0.2 0.42 10.9 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 EMR65520.1 - 0.16 12.7 3.0 0.48 11.2 2.1 2.0 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 EMR65520.1 - 0.18 11.6 0.2 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 SHS2_Rpb7-N PF03876.12 EMR65523.1 - 1.6e-15 56.9 0.0 3e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EMR65523.1 - 3.5e-11 43.0 0.0 5.1e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain LAM_C PF12544.3 EMR65524.1 - 2.4e-05 24.3 0.0 4.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.16 EMR65524.1 - 0.0005 20.2 0.0 0.00099 19.3 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EMR65524.1 - 0.037 14.0 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_12 PF13353.1 EMR65524.1 - 0.042 13.9 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF962 PF06127.6 EMR65525.1 - 9.8e-09 34.9 0.1 1.2e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) SNF5 PF04855.7 EMR65526.1 - 3.8e-73 245.9 0.2 7.6e-73 244.9 0.1 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 TolB_N PF04052.8 EMR65526.1 - 0.1 12.6 0.0 2.9 8.0 0.0 2.6 1 1 1 2 2 2 0 TolB amino-terminal domain TraV PF09676.5 EMR65526.1 - 4.6 7.9 7.5 1 10.0 2.6 1.8 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Peptidase_M24 PF00557.19 EMR65527.1 - 4.6e-10 39.4 0.1 6.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Epimerase PF01370.16 EMR65528.1 - 9.4e-56 188.8 0.0 1.2e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR65528.1 - 1e-21 76.8 0.0 1.4e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMR65528.1 - 1.1e-21 76.9 0.3 7.9e-21 74.1 0.2 1.9 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EMR65528.1 - 5.6e-21 74.7 0.0 6.1e-20 71.3 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EMR65528.1 - 1e-18 67.2 0.0 1.4e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EMR65528.1 - 1.2e-08 35.1 0.0 2.1e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMR65528.1 - 0.0022 17.9 0.0 0.036 13.9 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EMR65528.1 - 0.038 13.2 0.1 0.074 12.2 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family PHD PF00628.24 EMR65529.1 - 3.8e-14 52.0 17.5 1.4e-08 34.2 6.9 2.4 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.1 EMR65529.1 - 0.011 15.8 8.3 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-PHD-like PF15446.1 EMR65529.1 - 0.014 14.6 8.2 0.086 12.1 2.0 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.6 EMR65529.1 - 0.027 14.4 0.6 0.027 14.4 0.4 2.5 2 0 0 2 2 2 0 RING-like domain PHD_2 PF13831.1 EMR65529.1 - 0.19 11.0 8.2 1.4 8.2 3.0 2.8 2 0 0 2 2 2 0 PHD-finger Glyco_tranf_2_5 PF13712.1 EMR65530.1 - 0.047 12.9 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family AAA PF00004.24 EMR65531.1 - 2e-14 53.9 0.0 3.6e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR65531.1 - 0.00059 19.9 1.0 0.022 14.9 0.7 2.6 1 1 0 1 1 1 1 AAA domain Torsin PF06309.6 EMR65531.1 - 0.00098 19.0 0.0 0.0027 17.6 0.0 1.7 1 1 0 1 1 1 1 Torsin AAA_5 PF07728.9 EMR65531.1 - 0.018 14.7 0.0 0.044 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EMR65531.1 - 0.018 14.9 0.1 0.23 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EMR65531.1 - 0.023 14.1 0.0 0.051 13.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Phage_int_SAM_2 PF12834.2 EMR65531.1 - 0.025 14.9 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal AAA_16 PF13191.1 EMR65531.1 - 0.025 14.5 0.1 0.056 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EMR65531.1 - 0.027 14.1 0.1 0.11 12.2 0.0 2.0 3 0 0 3 3 3 0 Part of AAA domain DUF4135 PF13575.1 EMR65531.1 - 0.056 12.4 0.1 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) CPT PF07931.7 EMR65531.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein T2SE PF00437.15 EMR65531.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 EMR65531.1 - 0.11 11.8 0.2 0.22 10.9 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein Acetyltransf_1 PF00583.19 EMR65532.1 - 3.4e-11 42.9 0.0 5.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMR65532.1 - 4.3e-10 39.7 0.0 6.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR65532.1 - 7.7e-08 32.4 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMR65532.1 - 2.3e-06 27.6 0.0 4.1e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMR65532.1 - 7.3e-06 25.9 0.1 1.1e-05 25.3 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMR65532.1 - 6.3e-05 23.1 0.0 8.4e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR65532.1 - 0.018 14.9 0.1 0.077 12.8 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Lactamase_B_4 PF13691.1 EMR65532.1 - 0.045 13.2 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 tRNase Z endonuclease FR47 PF08445.5 EMR65532.1 - 0.13 12.0 0.0 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein Pep3_Vps18 PF05131.9 EMR65533.1 - 9.3e-47 158.1 0.0 2e-46 157.0 0.0 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EMR65533.1 - 1.9e-09 37.2 6.1 1e-07 31.6 0.0 3.5 3 2 1 4 4 4 1 Region in Clathrin and VPS Methyltransf_18 PF12847.2 EMR65533.1 - 8.7e-06 26.2 0.0 7.1e-05 23.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR65533.1 - 4.9e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR65533.1 - 8.3e-05 22.9 0.2 0.00044 20.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMR65533.1 - 0.00057 18.9 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EMR65533.1 - 0.0066 16.0 0.0 0.031 13.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain zf-RING_2 PF13639.1 EMR65533.1 - 0.016 15.0 1.0 0.016 15.0 0.7 1.8 2 0 0 2 2 1 0 Ring finger domain CMAS PF02353.15 EMR65533.1 - 0.017 14.1 0.2 0.037 13.0 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase zf-RING_5 PF14634.1 EMR65533.1 - 0.019 14.6 0.7 0.042 13.5 0.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.2 EMR65533.1 - 0.1 12.7 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger YEATS PF03366.11 EMR65534.1 - 3.1e-11 42.8 0.7 5.2e-11 42.1 0.5 1.3 1 0 0 1 1 1 1 YEATS family Abhydrolase_6 PF12697.2 EMR65536.1 - 5.3e-21 75.5 5.6 7.2e-21 75.1 3.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR65536.1 - 4.7e-11 42.6 4.1 2e-10 40.5 2.9 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR65536.1 - 1.2e-06 28.2 3.0 2e-06 27.5 2.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EMR65536.1 - 0.00016 21.2 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_8 PF06259.7 EMR65536.1 - 0.0014 18.1 1.2 0.0021 17.5 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase PGAP1 PF07819.8 EMR65536.1 - 0.0096 15.5 0.1 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S15 PF02129.13 EMR65536.1 - 0.032 13.6 0.5 0.17 11.3 0.3 1.9 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF676 PF05057.9 EMR65536.1 - 0.048 12.9 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF914 PF06027.7 EMR65538.1 - 5.4e-101 337.7 20.0 7.1e-101 337.4 13.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EMR65538.1 - 6.3e-05 23.0 10.4 6.3e-05 23.0 7.2 2.5 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 EMR65538.1 - 0.012 15.2 1.8 0.012 15.2 1.3 2.9 3 1 0 3 3 3 0 Triose-phosphate Transporter family FUSC-like PF12805.2 EMR65538.1 - 1.1 8.1 9.8 0.054 12.4 2.0 2.1 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Methyltransf_2 PF00891.13 EMR65540.1 - 7.5e-29 100.6 0.0 1.1e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Glyco_hydro_47 PF01532.15 EMR65541.1 - 4.6e-18 65.1 0.0 5e-18 64.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TPR_1 PF00515.23 EMR65542.1 - 1.1e-49 164.1 19.6 3.2e-08 32.8 0.0 9.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 EMR65542.1 - 2.9e-41 136.0 15.2 1e-05 25.0 0.0 9.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 EMR65542.1 - 2.7e-39 132.6 14.9 5.4e-14 51.5 1.0 5.7 2 2 2 5 5 5 5 TPR repeat TPR_8 PF13181.1 EMR65542.1 - 1.1e-35 118.7 13.2 5.8e-06 25.7 0.5 9.4 8 1 1 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 EMR65542.1 - 2e-27 95.2 10.3 5.6e-05 23.6 0.3 6.7 5 2 2 7 7 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 EMR65542.1 - 1.1e-25 89.3 18.9 1.7e-06 27.9 0.1 6.5 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 EMR65542.1 - 1.3e-25 87.4 8.1 0.01 15.9 0.1 9.0 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_14 PF13428.1 EMR65542.1 - 2.8e-25 86.4 7.2 0.00072 19.9 0.0 8.7 4 3 5 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.1 EMR65542.1 - 7.3e-23 80.7 5.9 0.0001 22.5 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 EMR65542.1 - 1.6e-20 71.2 8.0 0.0012 18.5 0.0 8.4 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 EMR65542.1 - 3.6e-19 67.8 14.2 0.0021 18.4 0.0 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 EMR65542.1 - 3.9e-17 62.1 5.7 1.6e-08 34.5 0.8 3.5 3 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EMR65542.1 - 4.1e-11 42.4 2.6 0.00044 19.3 0.0 3.9 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 EMR65542.1 - 1.2e-10 41.0 8.4 0.00055 19.7 0.1 6.0 1 1 7 8 8 8 4 Tetratricopeptide repeat TPR_20 PF14561.1 EMR65542.1 - 3.6e-06 26.9 0.6 0.42 10.7 0.1 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.4 EMR65542.1 - 0.00024 21.0 12.6 0.12 12.3 1.5 4.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMR65542.1 - 0.2 11.6 15.3 14 5.7 0.1 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat Aldedh PF00171.17 EMR65543.1 - 2e-169 563.8 0.5 2.3e-169 563.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF126 PF01989.11 EMR65543.1 - 3.5 7.3 5.0 44 3.8 0.3 3.6 3 1 1 4 4 4 0 Protein of unknown function DUF126 CDK2AP PF09806.4 EMR65545.1 - 0.057 13.6 4.2 0.1 12.8 2.9 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein RRF PF01765.14 EMR65546.1 - 1e-14 54.3 1.2 1.3e-09 37.7 0.0 2.2 1 1 1 2 2 2 2 Ribosome recycling factor MFS_1 PF07690.11 EMR65547.1 - 1.7e-27 96.0 61.2 1.2e-26 93.3 28.2 3.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2243 PF10002.4 EMR65547.1 - 0.011 15.4 0.1 0.034 13.9 0.1 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2243) DUF3784 PF12650.2 EMR65547.1 - 3.8 7.5 12.2 0.5 10.3 0.1 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) GFO_IDH_MocA PF01408.17 EMR65548.1 - 3.3e-16 59.9 0.2 1.1e-15 58.1 0.1 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMR65548.1 - 0.032 14.0 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain QRPTase_C PF01729.14 EMR65548.1 - 0.096 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF3669 PF12417.3 EMR65548.1 - 0.14 11.9 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 Zinc finger protein DUF4066 PF13278.1 EMR65550.1 - 2.5e-18 65.8 0.0 3.4e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EMR65550.1 - 7.6e-11 41.6 0.0 1e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EMR65550.1 - 0.0076 15.7 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S8 PF00082.17 EMR65551.1 - 2.2e-31 109.0 9.8 2.2e-31 109.0 6.8 1.6 2 0 0 2 2 2 1 Subtilase family Defensin_propep PF00879.13 EMR65551.1 - 0.043 13.7 0.4 0.13 12.2 0.3 1.8 1 0 0 1 1 1 0 Defensin propeptide Exo_endo_phos PF03372.18 EMR65552.1 - 8.8e-09 35.6 0.1 1.5e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thiolase_C PF02803.13 EMR65553.1 - 1.3e-11 43.9 0.4 5.9e-11 41.8 0.0 2.3 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EMR65553.1 - 1.1e-05 24.9 0.1 0.00089 18.8 0.0 2.6 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EMR65553.1 - 9.8e-05 21.4 0.3 0.00021 20.3 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EMR65553.1 - 0.00039 19.9 0.1 0.0012 18.4 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMR65553.1 - 0.0029 17.4 0.1 0.072 12.9 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Polysacc_lyase PF14099.1 EMR65554.1 - 2.1e-36 125.6 2.9 2.5e-36 125.4 2.0 1.0 1 0 0 1 1 1 1 Polysaccharide lyase P16-Arc PF04699.9 EMR65555.1 - 1.4e-57 194.0 0.0 1.6e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Tcf25 PF04910.9 EMR65556.1 - 5.4e-73 246.0 0.0 1.1e-72 244.9 0.0 1.5 1 0 0 1 1 1 1 Transcriptional repressor TCF25 NST1 PF13945.1 EMR65556.1 - 0.2 11.7 6.8 0.45 10.5 4.7 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF4544 PF15077.1 EMR65556.1 - 0.55 9.7 4.3 1.1 8.6 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Glypican PF01153.14 EMR65556.1 - 1 7.8 3.5 2 6.9 2.4 1.4 1 0 0 1 1 1 0 Glypican Fungal_trans PF04082.13 EMR65557.1 - 5.1e-20 71.4 0.3 7.7e-20 70.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_8 PF01501.15 EMR65558.1 - 4e-20 72.2 0.0 1.6e-15 57.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 8 adh_short PF00106.20 EMR65559.1 - 1.3e-22 80.5 0.1 6.9e-22 78.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR65559.1 - 2.8e-14 53.1 0.0 4.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR65559.1 - 1e-08 35.2 0.1 3.4e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR65559.1 - 9.1e-05 22.0 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMR65559.1 - 0.00087 18.2 0.2 0.0013 17.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMR65559.1 - 0.01 15.8 0.1 0.057 13.4 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding SASP PF00269.15 EMR65559.1 - 0.013 15.3 0.5 5.7 6.8 0.0 2.8 2 0 0 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type 3Beta_HSD PF01073.14 EMR65559.1 - 0.021 13.5 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Phage_GP20 PF06810.6 EMR65559.1 - 0.027 13.9 0.1 0.041 13.3 0.1 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Methyltransf_11 PF08241.7 EMR65560.1 - 6.7e-07 29.7 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR65560.1 - 1.8e-06 27.7 0.0 2.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR65560.1 - 4.8e-05 23.7 0.0 7.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR65560.1 - 0.00047 19.7 0.0 0.00075 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain HMA PF00403.21 EMR65562.1 - 5.2e-15 55.3 1.0 6.8e-15 54.9 0.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain NQRA_SLBB PF11973.3 EMR65563.1 - 0.15 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 NQRA C-terminal domain DnaJ PF00226.26 EMR65564.1 - 1.4e-13 50.3 0.9 2.7e-13 49.4 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain CorA PF01544.13 EMR65564.1 - 0.051 12.5 0.6 0.07 12.1 0.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CENP-F_leu_zip PF10473.4 EMR65564.1 - 0.077 12.8 5.2 0.4 10.5 0.0 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3504 PF12012.3 EMR65564.1 - 0.4 10.4 4.0 0.1 12.3 0.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) DUF3899 PF13038.1 EMR65564.1 - 1.4 9.0 4.2 1.4 9.1 1.5 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) Adaptin_N PF01602.15 EMR65565.1 - 1.1e-121 406.7 7.8 1.3e-121 406.4 5.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EMR65565.1 - 4.3e-46 155.5 0.0 1.6e-45 153.7 0.0 2.0 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EMR65565.1 - 1.4e-18 67.2 0.0 2.7e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Apc13p PF05839.6 EMR65566.1 - 6.3e-35 119.0 0.3 7.3e-35 118.8 0.2 1.0 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.11 EMR65567.1 - 1.7e-34 118.5 0.0 2.1e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CRAL_TRIO PF00650.15 EMR65568.1 - 1.5e-42 144.7 0.0 3e-42 143.7 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMR65568.1 - 2.9e-07 30.5 0.4 2.9e-07 30.5 0.3 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EMR65568.1 - 3.2e-06 27.1 0.0 4.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.5 EMR65569.1 - 1.7e-54 185.0 2.6 7.2e-31 107.6 0.0 2.1 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EMR65569.1 - 1.2e-15 57.4 0.0 1.8e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Flavokinase PF01687.12 EMR65571.1 - 5.4e-35 119.9 0.0 6.8e-35 119.6 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase DUF1180 PF06679.7 EMR65571.1 - 1.7 8.4 7.2 3.1 7.6 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2413 PF10310.4 EMR65571.1 - 3.6 6.3 7.7 4.5 5.9 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF605 PF04652.11 EMR65571.1 - 6.1 6.1 16.3 8.1 5.7 11.3 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 EMR65571.1 - 6.2 4.9 6.0 7.6 4.6 4.2 1.0 1 0 0 1 1 1 0 Transmembrane protein SPX PF03105.14 EMR65573.1 - 1.8e-25 90.2 11.9 2.8e-21 76.5 8.3 2.4 1 1 0 1 1 1 1 SPX domain Ank_2 PF12796.2 EMR65573.1 - 5.1e-09 36.3 0.2 8.8e-08 32.3 0.1 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMR65573.1 - 1.7e-08 34.4 0.2 6.1e-05 23.1 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR65573.1 - 4.7e-08 33.3 0.1 2.2e-06 28.0 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EMR65573.1 - 5.1e-06 26.0 1.0 0.0019 17.8 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EMR65573.1 - 0.00021 21.1 0.9 0.013 15.7 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat Rsa3 PF14615.1 EMR65573.1 - 0.24 10.6 1.6 0.56 9.5 0.2 2.2 2 0 0 2 2 2 0 Ribosome-assembly protein 3 MFS_1 PF07690.11 EMR65575.1 - 8.5e-34 116.8 36.2 8.5e-34 116.8 25.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 EMR65575.1 - 0.058 13.4 5.0 0.11 12.5 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) ABM PF03992.11 EMR65576.1 - 1e-05 25.4 1.2 1e-05 25.4 0.8 1.4 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Citrate_synt PF00285.16 EMR65577.1 - 5.3e-101 337.8 0.0 6.9e-101 337.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EMR65577.1 - 0.038 13.4 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Fungal_trans PF04082.13 EMR65579.1 - 2.2e-10 39.8 0.1 3.6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Microtub_assoc PF07989.6 EMR65580.1 - 9.1e-05 22.2 2.7 0.00019 21.1 1.9 1.6 1 0 0 1 1 1 1 Microtubule associated bZIP_1 PF00170.16 EMR65580.1 - 0.0062 16.4 5.1 0.029 14.3 1.1 3.0 2 1 1 3 3 3 1 bZIP transcription factor Fmp27_WPPW PF10359.4 EMR65580.1 - 0.011 14.1 2.3 0.014 13.8 1.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF904 PF06005.7 EMR65580.1 - 0.017 15.4 7.4 0.3 11.3 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 EMR65580.1 - 0.031 14.1 3.2 0.031 14.1 2.3 2.9 3 1 2 5 5 5 0 Basic region leucine zipper FadA PF09403.5 EMR65580.1 - 0.37 10.8 5.5 0.14 12.1 1.7 1.9 2 0 0 2 2 2 0 Adhesion protein FadA DUF2072 PF09845.4 EMR65580.1 - 0.49 10.3 2.5 0.85 9.5 1.7 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Atg14 PF10186.4 EMR65580.1 - 0.74 8.7 3.4 1.1 8.0 2.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EMR65580.1 - 4.6 6.7 6.9 10 5.6 4.8 1.5 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EMR65580.1 - 7.7 6.0 10.1 6.4 6.3 0.8 2.4 1 1 1 2 2 2 0 Septum formation initiator E1-E2_ATPase PF00122.15 EMR65581.1 - 1.9e-62 210.3 5.9 4.3e-62 209.1 4.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMR65581.1 - 1.3e-22 81.3 0.0 3.1e-22 80.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMR65581.1 - 3.3e-13 50.2 0.0 8.4e-13 48.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMR65581.1 - 2.4e-10 39.7 0.0 6.3e-10 38.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMR65581.1 - 0.0013 18.3 0.1 0.0028 17.2 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RRM_5 PF13893.1 EMR65582.1 - 2.5e-06 27.2 0.0 4.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR65582.1 - 1.3e-05 24.7 0.0 2.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EMR65582.1 - 5.8e-05 23.2 0.2 0.00017 21.7 0.1 1.8 1 1 0 1 1 1 1 RNA polymerase II-binding domain. RRM_6 PF14259.1 EMR65582.1 - 0.00041 20.2 0.0 0.00083 19.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.22 EMR65583.1 - 5.3e-27 93.3 4.5 1.8e-11 43.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MatE PF01554.13 EMR65584.1 - 2.6e-05 23.8 0.2 3.5e-05 23.4 0.2 1.2 1 0 0 1 1 1 1 MatE PDCD2_C PF04194.8 EMR65585.1 - 5.2e-49 165.9 0.4 3.6e-48 163.2 0.0 2.4 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain MgtE_N PF03448.12 EMR65586.1 - 0.0053 17.0 4.4 0.99 9.7 0.1 2.1 1 1 1 2 2 2 2 MgtE intracellular N domain Beta_elim_lyase PF01212.16 EMR65586.1 - 3.5 6.6 15.5 4.4e+03 -3.5 10.7 2.9 1 1 0 1 1 1 0 Beta-eliminating lyase TBCC PF07986.7 EMR65588.1 - 8.9e-31 105.7 0.0 1.4e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TFIIA PF03153.8 EMR65588.1 - 0.047 13.5 2.6 0.061 13.2 1.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3439 PF11921.3 EMR65588.1 - 0.29 10.8 5.8 0.55 9.9 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 EMR65588.1 - 1.3 6.6 6.2 1.6 6.3 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Chitin_synth_1 PF01644.12 EMR65589.1 - 2.1e-67 226.0 0.0 3.1e-67 225.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EMR65589.1 - 1.9e-26 92.5 0.0 2.9e-21 75.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 EMR65589.1 - 1.1e-25 89.1 0.0 2.2e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EMR65589.1 - 2.3e-12 47.0 1.5 2.6e-12 46.8 0.0 1.9 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMR65589.1 - 1.4e-08 34.8 0.0 2.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Med9 PF07544.8 EMR65590.1 - 7.3e-19 67.2 0.1 1.5e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 HemX PF04375.9 EMR65590.1 - 0.043 12.4 6.5 0.057 11.9 4.5 1.1 1 0 0 1 1 1 0 HemX DUF812 PF05667.6 EMR65590.1 - 0.044 12.2 0.3 0.053 12.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1178 PF06676.6 EMR65590.1 - 0.23 11.6 3.1 0.53 10.4 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) Dicty_REP PF05086.7 EMR65590.1 - 0.26 9.0 6.2 0.3 8.7 4.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PAP1 PF08601.5 EMR65590.1 - 6.5 6.3 11.4 8.2 5.9 7.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 iPGM_N PF06415.8 EMR65591.1 - 4.7e-74 248.4 0.0 6.7e-74 247.9 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 EMR65591.1 - 3.2e-72 242.9 0.0 3.6e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 EMR65591.1 - 4.2e-06 26.3 0.0 1.4e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMR65591.1 - 9.5e-06 24.9 0.0 4.6e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.7 EMR65591.1 - 0.099 12.2 0.0 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 PglZ domain PCI_Csn8 PF10075.4 EMR65592.1 - 1.9e-37 128.2 0.0 2.7e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EMR65592.1 - 6.6e-21 74.8 0.0 8.7e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family MFS_1 PF07690.11 EMR65593.1 - 6.8e-13 48.0 41.4 2.6e-11 42.8 28.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily HATPase_c PF02518.21 EMR65594.1 - 2.3e-21 75.5 0.0 4.5e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMR65594.1 - 3e-16 59.4 0.1 9.6e-16 57.7 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain PAS_8 PF13188.1 EMR65594.1 - 1.4e-06 27.9 0.0 0.018 14.9 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_9 PF13426.1 EMR65594.1 - 1.9e-05 24.9 0.0 0.0013 19.0 0.0 2.7 2 0 0 2 2 2 1 PAS domain HisKA PF00512.20 EMR65594.1 - 0.098 12.6 0.1 0.26 11.3 0.0 1.8 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Fer2 PF00111.22 EMR65595.1 - 8.9e-12 44.5 1.5 4.5e-11 42.3 1.2 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.19 EMR65595.1 - 3.3e-05 23.9 0.0 6.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain MOSC PF03473.12 EMR65595.1 - 4e-05 23.0 0.0 8.3e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 MOSC domain NAD_binding_1 PF00175.16 EMR65595.1 - 0.00062 20.3 0.0 0.0022 18.5 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EMR65595.1 - 0.00067 19.6 0.7 0.026 14.4 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Transferase PF02458.10 EMR65596.1 - 2.3e-30 105.3 0.0 3e-12 45.7 0.0 3.1 3 0 0 3 3 3 3 Transferase family Aldo_ket_red PF00248.16 EMR65597.1 - 9.2e-58 195.2 0.0 1.2e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UFD1 PF03152.9 EMR65598.1 - 1.4e-25 89.4 0.0 1.8e-10 40.2 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin fusion degradation protein UFD1 zf-Mss51 PF13824.1 EMR65598.1 - 2.1 8.2 11.9 0.91 9.4 3.0 2.8 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Aldose_epim PF01263.15 EMR65599.1 - 1.6e-45 155.5 0.0 1.7e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Actin PF00022.14 EMR65600.1 - 6.3e-100 334.3 0.0 7.4e-100 334.1 0.0 1.0 1 0 0 1 1 1 1 Actin zf-B_box PF00643.19 EMR65601.1 - 3.5 7.6 10.3 1.3 8.9 4.6 2.2 2 0 0 2 2 2 0 B-box zinc finger adh_short PF00106.20 EMR65603.1 - 1.1e-25 90.5 3.1 1.3e-25 90.2 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR65603.1 - 8.9e-22 78.0 0.0 1.8e-21 77.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR65603.1 - 5.5e-12 45.7 1.2 1.1e-11 44.7 0.9 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR65603.1 - 0.0035 16.7 0.1 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EMR65603.1 - 0.0042 16.2 0.0 0.0067 15.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EMR65603.1 - 0.0049 15.9 0.2 0.008 15.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EMR65603.1 - 0.0071 15.2 0.0 0.0095 14.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMR65603.1 - 0.0084 14.8 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EMR65603.1 - 0.014 15.2 0.2 0.022 14.6 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 EMR65603.1 - 0.054 13.5 0.4 0.084 12.8 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding F420_oxidored PF03807.12 EMR65603.1 - 0.097 13.1 0.2 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 EMR65603.1 - 0.11 11.3 0.4 0.32 9.8 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain Shikimate_DH PF01488.15 EMR65603.1 - 0.15 12.1 0.2 0.3 11.1 0.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 EMR65604.1 - 3.1e-88 296.3 21.5 3.6e-88 296.1 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR65604.1 - 3.7e-26 91.6 30.7 7.9e-25 87.3 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 EMR65605.1 - 6.1e-32 109.6 0.4 6.1e-32 109.6 0.2 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR65605.1 - 6.6e-24 83.9 0.4 1.1e-23 83.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR65605.1 - 2.7e-07 31.5 0.0 7.1e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CMAS PF02353.15 EMR65605.1 - 0.00019 20.6 0.0 0.0003 19.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase 2-Hacid_dh_C PF02826.14 EMR65605.1 - 0.0051 15.9 0.1 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 EMR65605.1 - 0.0053 17.3 0.1 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR65605.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR65605.1 - 0.012 16.1 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMR65605.1 - 0.084 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EMR65605.1 - 0.086 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.16 EMR65605.1 - 0.51 10.1 3.1 1.8 8.4 0.6 2.4 2 1 1 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AAA_19 PF13245.1 EMR65606.1 - 2.7e-06 27.0 0.5 8e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EMR65606.1 - 2.8e-06 28.1 0.1 1e-05 26.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMR65606.1 - 4.3e-05 23.4 0.1 0.00024 20.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMR65606.1 - 6.1e-05 22.5 0.0 8.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMR65606.1 - 9.7e-05 21.5 0.1 0.00019 20.5 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EMR65606.1 - 0.00047 20.4 0.0 0.0014 18.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EMR65606.1 - 0.00057 20.0 0.0 0.0014 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EMR65606.1 - 0.001 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMR65606.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EMR65606.1 - 0.0014 18.1 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA PF00004.24 EMR65606.1 - 0.0017 18.5 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EMR65606.1 - 0.0019 17.6 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PRK PF00485.13 EMR65606.1 - 0.0072 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.1 EMR65606.1 - 0.009 16.3 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EMR65606.1 - 0.013 14.5 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_28 PF13521.1 EMR65606.1 - 0.014 15.4 0.2 0.054 13.4 0.0 1.8 1 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EMR65606.1 - 0.014 15.0 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 EMR65606.1 - 0.015 14.1 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_31 PF13614.1 EMR65606.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 EMR65606.1 - 0.02 14.3 0.3 0.027 13.8 0.2 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.5 EMR65606.1 - 0.021 14.0 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.9 EMR65606.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EMR65606.1 - 0.025 13.4 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EMR65606.1 - 0.031 13.8 0.0 0.055 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EMR65606.1 - 0.04 12.8 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PhoH PF02562.11 EMR65606.1 - 0.041 13.0 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 EMR65606.1 - 0.058 13.2 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 EMR65606.1 - 0.06 12.9 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMR65606.1 - 0.076 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 EMR65606.1 - 0.081 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EMR65606.1 - 0.089 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EMR65606.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.7 EMR65606.1 - 0.13 11.3 0.1 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 EMR65606.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_11 PF13086.1 EMR65606.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EMR65606.1 - 0.15 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 EMR65606.1 - 0.15 11.6 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 EMR65606.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 KaiC Ubiquitin_2 PF14560.1 EMR65607.1 - 0.064 13.5 0.0 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like domain Stimulus_sens_1 PF13756.1 EMR65607.1 - 0.07 13.5 0.0 0.26 11.6 0.0 2.0 2 1 0 2 2 2 0 Stimulus-sensing domain OPT PF03169.10 EMR65608.1 - 7.1e-129 431.0 34.3 8.1e-129 430.8 23.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase PF00069.20 EMR65609.1 - 3.7e-54 183.6 0.0 8.3e-54 182.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR65609.1 - 1.5e-29 102.8 0.0 2.3e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR65609.1 - 2.3e-10 39.9 0.0 3.5e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMR65609.1 - 0.08 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aa_trans PF01490.13 EMR65611.1 - 8.4e-45 152.9 24.6 8.4e-23 80.4 6.9 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EMR65611.1 - 8.5e-05 21.5 20.1 0.0031 16.3 3.9 2.2 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family ATP-synt_DE_N PF02823.11 EMR65612.1 - 6e-21 74.0 0.1 8.4e-21 73.5 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 2Fe-2S_Ferredox PF11591.3 EMR65612.1 - 6.8 6.4 7.2 5.3 6.7 3.4 1.9 2 0 0 2 2 2 0 Ferredoxin chloroplastic transit peptide Opi1 PF08618.5 EMR65613.1 - 0.053 12.4 20.5 0.035 13.0 12.5 1.8 1 1 1 2 2 2 0 Transcription factor Opi1 Macoilin PF09726.4 EMR65613.1 - 0.16 10.1 11.0 0.18 10.0 7.6 1.0 1 0 0 1 1 1 0 Transmembrane protein CDC27 PF09507.5 EMR65613.1 - 0.55 9.4 7.9 0.71 9.0 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SRP-alpha_N PF04086.8 EMR65613.1 - 0.59 9.4 4.6 0.77 9.0 3.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DNA_pol_viral_N PF00242.12 EMR65613.1 - 1 8.2 5.2 1.1 8.2 3.6 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Sec10 PF07393.6 EMR65613.1 - 1.3 7.1 4.0 1.5 6.9 2.8 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Peptidase_S64 PF08192.6 EMR65613.1 - 3.2 5.9 7.8 3.9 5.6 5.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF3827 PF12877.2 EMR65613.1 - 5.3 5.0 8.1 6.9 4.6 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) ABC_tran PF00005.22 EMR65614.1 - 7.5e-34 116.9 0.0 1.5e-33 115.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EMR65614.1 - 6.5e-26 91.3 6.7 9.6e-26 90.7 4.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EMR65614.1 - 3.8e-05 23.7 0.1 0.043 13.7 0.0 2.7 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EMR65614.1 - 0.0013 18.7 0.0 0.0034 17.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 EMR65614.1 - 0.0015 17.8 0.1 0.028 13.6 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EMR65614.1 - 0.0015 17.7 0.0 0.0033 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMR65614.1 - 0.0027 17.2 0.1 0.0073 15.8 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EMR65614.1 - 0.0098 15.7 1.6 0.048 13.5 0.1 2.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF815 PF05673.8 EMR65614.1 - 0.016 14.1 0.1 0.048 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 EMR65614.1 - 0.027 13.9 0.0 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 EMR65614.1 - 0.068 13.3 0.2 0.52 10.4 0.1 2.3 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EMR65614.1 - 0.21 11.0 1.4 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FDF PF09532.5 EMR65615.1 - 3 8.4 7.9 7.6 7.1 2.2 2.5 2 0 0 2 2 2 0 FDF domain Pex14_N PF04695.8 EMR65615.1 - 9.7 6.2 11.5 11 6.0 3.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Arf PF00025.16 EMR65616.1 - 1.2e-66 223.2 0.0 1.3e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EMR65616.1 - 4e-12 45.5 0.1 2e-08 33.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EMR65616.1 - 1.9e-08 33.7 0.0 2.5e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EMR65616.1 - 7.8e-08 32.8 0.0 1.1e-07 32.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMR65616.1 - 2.1e-07 30.9 0.0 2.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EMR65616.1 - 5.4e-07 29.1 0.0 7.2e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EMR65616.1 - 1e-05 24.8 0.0 1.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMR65616.1 - 0.0021 17.4 0.0 0.11 11.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EMR65616.1 - 0.08 12.4 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.3 EMR65616.1 - 0.088 12.0 0.0 0.21 10.7 0.0 1.5 2 0 0 2 2 2 0 Centromere protein M (CENP-M) AAA PF00004.24 EMR65617.1 - 1.4e-97 323.0 0.0 2e-47 160.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EMR65617.1 - 1.1e-19 70.1 0.8 3.5e-19 68.5 0.2 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EMR65617.1 - 8.4e-14 51.8 0.0 1.9e-07 31.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EMR65617.1 - 1.3e-13 50.5 0.0 3.5e-06 26.2 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EMR65617.1 - 1e-12 47.9 0.4 1.5e-06 28.0 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EMR65617.1 - 1.7e-12 47.3 0.0 3.1e-05 23.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EMR65617.1 - 7e-12 45.6 0.2 0.00068 19.7 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EMR65617.1 - 5.9e-11 43.2 0.0 0.00033 21.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMR65617.1 - 8e-11 42.2 0.0 0.00035 20.6 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 EMR65617.1 - 3e-09 36.1 0.1 0.0008 18.2 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EMR65617.1 - 9.4e-09 34.9 5.8 0.032 13.6 0.0 4.8 3 2 1 5 5 4 3 AAA domain IstB_IS21 PF01695.12 EMR65617.1 - 1.9e-08 33.9 0.0 0.0034 16.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EMR65617.1 - 3.4e-08 33.1 1.1 0.012 15.3 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain AAA_14 PF13173.1 EMR65617.1 - 5.1e-08 32.8 0.0 0.0014 18.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EMR65617.1 - 7e-08 31.8 0.0 0.0094 15.0 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin Mg_chelatase PF01078.16 EMR65617.1 - 1.8e-07 30.5 0.3 0.0065 15.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.12 EMR65617.1 - 3.2e-07 29.8 0.0 9.7e-07 28.3 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 KaiC PF06745.8 EMR65617.1 - 4.3e-07 29.2 0.6 0.22 10.6 0.0 3.5 2 1 1 3 3 3 2 KaiC DUF815 PF05673.8 EMR65617.1 - 5.2e-07 28.8 0.0 0.0015 17.5 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function (DUF815) AAA_18 PF13238.1 EMR65617.1 - 1.2e-06 28.9 0.0 0.069 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EMR65617.1 - 1.4e-06 28.4 0.0 0.076 13.1 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_28 PF13521.1 EMR65617.1 - 2.6e-06 27.4 0.1 0.072 13.0 0.0 2.7 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 EMR65617.1 - 2.8e-06 27.3 0.0 0.002 18.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 EMR65617.1 - 1e-05 25.6 0.0 0.044 13.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EMR65617.1 - 1.1e-05 25.6 0.0 0.15 12.3 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_24 PF13479.1 EMR65617.1 - 1.9e-05 24.3 1.1 0.14 11.7 0.0 3.3 4 0 0 4 4 2 2 AAA domain Parvo_NS1 PF01057.12 EMR65617.1 - 2.7e-05 23.1 0.0 0.17 10.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EMR65617.1 - 3e-05 23.5 0.0 0.2 11.1 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EMR65617.1 - 3.5e-05 23.6 0.1 5.7 6.5 0.0 4.0 2 2 2 4 4 4 0 Archaeal ATPase NACHT PF05729.7 EMR65617.1 - 3.6e-05 23.4 0.1 0.2 11.2 0.0 3.3 3 0 0 3 3 3 1 NACHT domain PhoH PF02562.11 EMR65617.1 - 7.9e-05 21.9 0.2 0.3 10.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Bac_DnaA PF00308.13 EMR65617.1 - 0.00013 21.7 0.0 0.25 10.9 0.0 3.1 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_3 PF07726.6 EMR65617.1 - 0.00023 20.7 0.0 0.56 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EMR65617.1 - 0.00027 20.5 0.0 0.68 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 EMR65617.1 - 0.00038 20.2 0.1 0.0019 18.0 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain NTPase_1 PF03266.10 EMR65617.1 - 0.0007 19.3 0.3 0.65 9.6 0.0 3.9 3 0 0 3 3 3 1 NTPase AAA_11 PF13086.1 EMR65617.1 - 0.00072 19.1 0.0 0.95 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EMR65617.1 - 0.0016 17.4 0.1 1.8 7.3 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain DUF2075 PF09848.4 EMR65617.1 - 0.0034 16.4 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EMR65617.1 - 0.0055 16.2 0.0 0.25 10.8 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 EMR65617.1 - 0.0094 14.9 0.3 1 8.2 0.0 3.1 2 2 1 3 3 3 1 KAP family P-loop domain IPT PF01745.11 EMR65617.1 - 0.01 15.0 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_10 PF12846.2 EMR65617.1 - 0.012 15.0 0.9 0.54 9.6 0.0 3.4 3 1 1 4 4 4 0 AAA-like domain UPF0079 PF02367.12 EMR65617.1 - 0.021 14.4 0.1 8.9 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EMR65617.1 - 0.038 12.8 0.0 1.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein KTI12 PF08433.5 EMR65617.1 - 0.081 12.1 0.7 5.7 6.0 0.0 2.8 3 0 0 3 3 2 0 Chromatin associated protein KTI12 Zot PF05707.7 EMR65617.1 - 0.09 12.2 0.2 13 5.1 0.1 3.8 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) MobB PF03205.9 EMR65617.1 - 0.097 12.3 0.7 2.8 7.6 0.0 3.2 4 0 0 4 4 2 0 Molybdopterin guanine dinucleotide synthesis protein B SKI PF01202.17 EMR65617.1 - 0.098 12.5 0.1 8.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AFG1_ATPase PF03969.11 EMR65617.1 - 0.11 11.2 0.0 13 4.4 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase ATP-synt_ab PF00006.20 EMR65617.1 - 0.13 11.7 0.0 4.7 6.6 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TRAM_LAG1_CLN8 PF03798.11 EMR65618.1 - 3.7e-35 121.2 22.3 3.7e-35 121.2 15.4 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EMR65618.1 - 7e-25 86.3 0.0 1.9e-24 84.9 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein DUF2457 PF10446.4 EMR65619.1 - 1e-93 314.6 60.8 2.4e-77 260.6 25.4 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 EMR65620.1 - 7.7 6.9 17.8 1 9.6 4.8 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Brix PF04427.13 EMR65621.1 - 2.2e-38 131.8 0.0 2.9e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain Hist_deacetyl PF00850.14 EMR65622.1 - 5.2e-91 305.1 0.0 7.2e-91 304.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EMR65622.1 - 2.1e-40 138.0 0.0 3.1e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain cwf21 PF08312.7 EMR65623.1 - 0.022 14.6 0.8 0.022 14.6 0.6 2.4 2 0 0 2 2 2 0 cwf21 domain Troponin PF00992.15 EMR65623.1 - 0.022 14.8 6.0 0.022 14.8 4.2 1.6 2 0 0 2 2 2 0 Troponin DUF2526 PF10735.4 EMR65623.1 - 0.14 12.1 1.3 0.42 10.6 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) PAT1 PF09770.4 EMR65623.1 - 0.16 10.1 9.5 0.2 9.8 6.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-box PF00646.28 EMR65624.1 - 0.0052 16.4 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain Ras PF00071.17 EMR65625.1 - 2.1e-63 212.5 0.2 2.5e-63 212.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR65625.1 - 2e-21 76.7 0.1 2.7e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMR65625.1 - 3.9e-13 49.0 0.1 5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMR65625.1 - 2.9e-08 33.6 0.1 4.9e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMR65625.1 - 4.6e-05 22.9 0.1 0.00016 21.2 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMR65625.1 - 9.8e-05 21.5 0.1 0.00017 20.8 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EMR65625.1 - 0.00012 22.2 0.1 0.00033 20.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMR65625.1 - 0.0015 18.4 0.1 0.0034 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EMR65625.1 - 0.0019 17.2 0.1 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EMR65625.1 - 0.0026 16.9 0.1 0.0062 15.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 EMR65625.1 - 0.0074 16.1 0.1 0.096 12.6 0.0 2.1 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 EMR65625.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EMR65625.1 - 0.017 14.6 0.1 0.053 13.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EMR65625.1 - 0.018 15.3 0.1 0.032 14.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EMR65625.1 - 0.024 14.5 0.4 0.046 13.7 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 EMR65625.1 - 0.088 12.0 0.1 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EMR65625.1 - 0.094 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EMR65625.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF1128 PF06569.6 EMR65625.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) HET PF06985.6 EMR65626.1 - 4.9e-10 39.7 0.0 1.3e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GIT_SHD PF08518.6 EMR65626.1 - 7.2 6.0 6.2 3.7 7.0 0.1 2.6 3 0 0 3 3 3 0 Spa2 homology domain (SHD) of GIT TauD PF02668.11 EMR65627.1 - 5.4e-45 154.0 0.4 2.7e-34 119.0 0.1 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family p450 PF00067.17 EMR65628.1 - 1.1e-27 96.6 0.0 1.4e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.12 EMR65629.1 - 5.6e-23 81.1 0.0 7.5e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.17 EMR65630.1 - 4.4e-57 193.6 0.0 6.4e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMR65631.1 - 5.2e-50 170.3 0.0 8e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EMR65632.1 - 2e-20 72.8 29.5 5.8e-19 68.0 20.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1049 PF06305.6 EMR65632.1 - 0.17 11.3 0.2 0.17 11.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) FAD_binding_3 PF01494.14 EMR65633.1 - 4.3e-31 108.2 2.0 3.8e-30 105.1 1.4 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR65633.1 - 3e-08 32.9 0.1 2.6e-05 23.2 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR65633.1 - 4.7e-07 29.7 1.0 4.3e-06 26.6 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMR65633.1 - 1.9e-06 27.2 0.8 0.024 13.7 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EMR65633.1 - 2.1e-05 23.6 0.8 0.013 14.4 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.2 EMR65633.1 - 0.00031 19.9 0.1 0.00048 19.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR65633.1 - 0.00041 18.9 0.2 0.0024 16.4 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EMR65633.1 - 0.0006 19.9 0.2 0.0017 18.4 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR65633.1 - 0.00072 19.9 2.2 0.0022 18.3 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR65633.1 - 0.00084 18.3 1.0 0.0028 16.5 0.7 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EMR65633.1 - 0.001 17.9 1.1 0.0022 16.8 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EMR65633.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR65633.1 - 0.0067 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.16 EMR65633.1 - 0.031 13.8 0.2 0.061 12.8 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EMR65633.1 - 0.034 12.7 0.0 0.066 11.8 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase p450 PF00067.17 EMR65634.1 - 2.6e-08 32.8 0.0 4.7e-08 31.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 SUR7 PF06687.7 EMR65635.1 - 2.9e-31 108.7 5.6 4.3e-31 108.1 3.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EMR65635.1 - 0.00023 20.9 9.8 0.00023 20.9 6.8 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction FliT PF05400.8 EMR65636.1 - 0.034 14.5 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein FliT p450 PF00067.17 EMR65637.1 - 4.7e-37 127.6 0.1 5.7e-37 127.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_21 PF05050.7 EMR65638.1 - 2.1e-22 79.8 0.0 2.9e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_18 PF12847.2 EMR65638.1 - 6.1e-07 30.0 0.0 9.1e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain V_cholerae_RfbT PF05575.6 EMR65638.1 - 0.0025 16.9 0.0 0.047 12.7 0.0 2.0 2 0 0 2 2 2 1 Vibrio cholerae RfbT protein MTS PF05175.9 EMR65638.1 - 0.0077 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 EMR65638.1 - 0.0083 15.7 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein SnoaL_2 PF12680.2 EMR65639.1 - 0.0004 20.7 0.0 0.00048 20.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EMR65639.1 - 0.01 15.4 0.0 0.014 14.9 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_4 PF13577.1 EMR65639.1 - 0.053 13.4 0.0 0.059 13.2 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Transferase PF02458.10 EMR65640.1 - 0.00018 20.0 0.0 0.00026 19.5 0.0 1.1 1 0 0 1 1 1 1 Transferase family adh_short PF00106.20 EMR65641.1 - 7.9e-13 48.6 0.0 1.6e-11 44.3 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR65641.1 - 8.2e-07 28.8 0.0 2.7e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 KR domain UDPGT PF00201.13 EMR65641.1 - 0.0025 16.4 0.0 0.0038 15.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Methyltransf_12 PF08242.7 EMR65642.1 - 1.3e-15 57.6 0.0 3.8e-15 56.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 EMR65642.1 - 4.5e-13 49.2 0.1 9.6e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_23 PF13489.1 EMR65642.1 - 1.4e-12 47.5 0.0 2.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR65642.1 - 7.1e-10 38.6 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR65642.1 - 6.3e-08 32.8 0.0 1.8e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 EMR65642.1 - 6.3e-08 32.4 0.1 1.4e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_11 PF08241.7 EMR65642.1 - 2.1e-06 28.1 0.0 4.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.16 EMR65642.1 - 9e-06 25.0 0.0 1.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Methyltransf_18 PF12847.2 EMR65642.1 - 1.3e-05 25.7 0.0 8.3e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Abhydrolase_6 PF12697.2 EMR65642.1 - 2.4e-05 24.3 2.1 0.0017 18.2 0.9 3.4 3 1 0 3 3 3 1 Alpha/beta hydrolase family Ubie_methyltran PF01209.13 EMR65642.1 - 0.00011 21.4 0.0 0.00028 20.0 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EMR65642.1 - 0.0005 19.5 0.0 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 EMR65642.1 - 0.0014 18.6 0.0 0.0071 16.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Abhydrolase_2 PF02230.11 EMR65642.1 - 0.018 14.5 0.0 0.56 9.6 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 EMR65642.1 - 0.056 12.7 0.0 0.22 10.7 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family RrnaAD PF00398.15 EMR65642.1 - 0.079 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF2984 PF11203.3 EMR65642.1 - 0.1 12.7 0.0 3.4 7.8 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2984) LIP PF03583.9 EMR65642.1 - 0.11 11.7 0.0 0.59 9.2 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase Epimerase PF01370.16 EMR65643.1 - 1.1e-26 93.7 0.0 4e-14 52.6 0.0 2.2 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMR65643.1 - 0.0092 14.9 0.0 0.021 13.7 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase_Csub PF13950.1 EMR65643.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit RRM_1 PF00076.17 EMR65644.1 - 0.00051 19.6 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Terpene_synth_C PF03936.11 EMR65645.1 - 9.5e-17 61.1 2.1 1.3e-16 60.6 1.5 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain ketoacyl-synt PF00109.21 EMR65646.1 - 1.5e-72 244.1 0.0 4.6e-72 242.5 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Carn_acyltransf PF00755.15 EMR65646.1 - 3.5e-72 243.3 0.0 4.8e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Acyl_transf_1 PF00698.16 EMR65646.1 - 1.1e-62 212.2 0.2 2.8e-62 210.9 0.1 1.7 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EMR65646.1 - 8e-53 179.5 0.0 1.6e-52 178.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EMR65646.1 - 2.2e-43 148.0 1.7 1.2e-42 145.5 0.2 3.0 3 0 0 3 3 3 1 KR domain Ketoacyl-synt_C PF02801.17 EMR65646.1 - 3.3e-37 126.9 0.1 1.4e-36 124.9 0.0 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EMR65646.1 - 5.9e-35 120.6 3.6 8.3e-34 116.9 0.7 3.2 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_12 PF08242.7 EMR65646.1 - 1.6e-09 38.1 0.0 1e-08 35.5 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR65646.1 - 1.5e-08 34.5 0.0 3.8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR65646.1 - 2e-08 34.3 0.1 5.3e-08 33.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EMR65646.1 - 8.4e-06 26.1 0.0 0.00023 21.6 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR65646.1 - 0.00014 21.5 0.0 0.00083 18.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.21 EMR65646.1 - 0.00028 20.4 0.0 0.0012 18.3 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.13 EMR65646.1 - 0.00061 18.9 0.0 0.0015 17.7 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EMR65646.1 - 0.0077 16.8 0.0 0.07 13.7 0.0 2.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EMR65646.1 - 0.029 14.1 0.0 0.076 12.7 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.14 EMR65646.1 - 0.17 10.5 0.0 0.29 9.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Calici_coat PF00915.15 EMR65647.1 - 0.024 13.5 0.1 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Calicivirus coat protein LRR_4 PF12799.2 EMR65648.1 - 0.085 12.5 1.7 0.82 9.3 0.0 3.1 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) AAA PF00004.24 EMR65649.1 - 1e-40 139.0 0.0 5.1e-16 59.0 0.0 4.8 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 EMR65649.1 - 3.9e-36 124.3 1.2 1.2e-35 122.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 EMR65649.1 - 1.1e-16 61.1 29.2 2.3e-14 53.5 0.0 6.7 5 1 0 5 5 5 1 AAA domain AAA_22 PF13401.1 EMR65649.1 - 2.1e-11 44.0 8.1 0.0041 17.2 0.3 6.6 4 3 0 4 4 3 3 AAA domain AAA_19 PF13245.1 EMR65649.1 - 4.1e-11 42.4 0.7 0.045 13.4 0.0 4.0 3 0 0 3 3 3 3 Part of AAA domain AAA_5 PF07728.9 EMR65649.1 - 1.5e-09 37.7 0.6 0.066 12.9 0.0 4.4 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMR65649.1 - 3.9e-09 37.3 6.7 0.069 13.9 0.0 4.7 4 0 0 4 4 3 3 AAA domain AAA_16 PF13191.1 EMR65649.1 - 7.7e-09 35.7 3.0 0.11 12.5 0.0 4.6 4 0 0 4 4 4 3 AAA ATPase domain Mg_chelatase PF01078.16 EMR65649.1 - 1.1e-08 34.4 0.0 0.04 13.0 0.0 3.6 3 0 0 3 3 3 3 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 EMR65649.1 - 1.7e-08 34.3 0.1 0.051 13.0 0.0 5.2 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EMR65649.1 - 1e-06 28.4 4.7 3.5 7.1 0.0 5.4 5 1 0 5 5 5 1 AAA domain RuvB_N PF05496.7 EMR65649.1 - 2.8e-06 26.5 0.0 0.38 9.7 0.0 3.9 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EMR65649.1 - 3.4e-06 26.9 1.8 0.48 10.2 0.0 4.3 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.1 EMR65649.1 - 8.7e-06 25.4 4.3 0.19 11.2 0.1 4.1 3 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 EMR65649.1 - 1.2e-05 25.3 0.1 1.5 9.0 0.0 3.9 3 0 0 3 3 3 2 RNA helicase IstB_IS21 PF01695.12 EMR65649.1 - 1.7e-05 24.3 0.1 1.8 7.9 0.0 3.6 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_10 PF12846.2 EMR65649.1 - 0.00027 20.5 5.3 7.8 5.8 0.1 6.1 5 1 1 6 6 6 0 AAA-like domain Torsin PF06309.6 EMR65649.1 - 0.00053 19.8 0.0 8.5 6.2 0.0 3.6 3 0 0 3 3 3 0 Torsin NTPase_1 PF03266.10 EMR65649.1 - 0.014 15.1 1.3 23 4.6 0.0 3.8 3 0 0 3 3 3 0 NTPase AAA_29 PF13555.1 EMR65649.1 - 0.016 14.7 0.1 12 5.5 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain SRP54 PF00448.17 EMR65649.1 - 0.1 12.0 4.0 0.36 10.2 0.0 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain MobB PF03205.9 EMR65649.1 - 0.12 12.0 3.0 14 5.3 0.0 4.0 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EMR65649.1 - 0.26 11.5 20.1 1.3 9.3 0.0 5.0 5 0 0 5 5 3 0 AAA domain AAA_25 PF13481.1 EMR65649.1 - 4.5 6.6 7.2 60 2.9 0.0 4.3 4 0 0 4 4 3 0 AAA domain Aldo_ket_red PF00248.16 EMR65650.1 - 1.5e-68 230.7 0.0 2e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.14 EMR65651.1 - 2.1e-25 89.4 0.0 3.4e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR65651.1 - 2.2e-21 76.6 0.8 4.5e-21 75.6 0.6 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMR65651.1 - 1.9e-07 30.3 4.0 1.5e-06 27.3 2.8 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EMR65651.1 - 1e-06 28.1 4.7 2.1e-06 27.1 3.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EMR65651.1 - 1.2e-06 27.6 1.7 0.00012 21.1 0.7 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR65651.1 - 2.2e-06 26.4 1.3 3.8e-06 25.6 0.9 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EMR65651.1 - 7.3e-06 25.0 0.1 1.1e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EMR65651.1 - 2.1e-05 23.7 0.8 3.9e-05 22.8 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMR65651.1 - 3.6e-05 23.7 1.1 9.5e-05 22.3 0.7 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR65651.1 - 0.00023 21.1 1.5 0.00061 19.7 1.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMR65651.1 - 0.00033 19.8 0.4 0.00066 18.8 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EMR65651.1 - 0.0018 17.2 1.0 0.0049 15.8 0.7 1.7 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EMR65651.1 - 0.0033 16.1 0.6 0.0052 15.4 0.4 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 EMR65651.1 - 0.0081 16.2 0.2 0.031 14.3 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR65651.1 - 0.041 14.2 0.3 0.14 12.5 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Raptor_N PF14538.1 EMR65652.1 - 6.4e-66 220.9 0.0 1.3e-65 220.0 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EMR65652.1 - 9.2e-10 38.0 3.0 0.7 9.8 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EMR65652.1 - 0.0073 16.0 0.1 1.7 8.4 0.1 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.1 EMR65652.1 - 0.0094 16.2 0.2 0.28 11.4 0.0 3.3 4 0 0 4 4 4 1 HEAT repeats Cnd1 PF12717.2 EMR65652.1 - 0.6 9.9 2.0 20 4.9 0.0 3.2 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Kelch_4 PF13418.1 EMR65653.1 - 3.1e-37 126.0 8.6 2.6e-08 33.5 0.3 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EMR65653.1 - 6.6e-33 112.1 16.4 3.5e-10 39.6 0.1 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.1 EMR65653.1 - 3.8e-32 109.6 12.4 1.5e-08 34.5 0.1 7.3 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_1 PF01344.20 EMR65653.1 - 9.2e-29 98.7 5.5 8.3e-11 41.2 0.3 6.7 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.1 EMR65653.1 - 1.2e-28 98.0 7.6 6.7e-12 45.0 0.4 6.8 6 1 1 7 7 7 6 Kelch motif Kelch_2 PF07646.10 EMR65653.1 - 6e-21 73.3 9.2 3.9e-08 32.7 0.1 6.7 6 1 0 6 6 6 5 Kelch motif RAG2 PF03089.9 EMR65653.1 - 0.0074 15.0 0.2 0.4 9.3 0.0 3.4 4 0 0 4 4 4 1 Recombination activating protein 2 NAD_binding_8 PF13450.1 EMR65654.1 - 3.2e-14 52.7 0.2 7.6e-14 51.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMR65654.1 - 2.7e-13 49.8 1.3 6.9e-13 48.4 0.1 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EMR65654.1 - 2.8e-13 49.5 0.8 8.9e-07 28.1 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR65654.1 - 5.3e-06 25.5 4.4 5.5e-05 22.1 2.0 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EMR65654.1 - 7.8e-06 24.6 0.9 0.0024 16.4 1.4 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EMR65654.1 - 2.8e-05 24.2 0.0 0.0028 17.7 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR65654.1 - 8e-05 22.5 0.0 0.00019 21.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMR65654.1 - 9.5e-05 21.6 5.4 0.01 14.9 3.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EMR65654.1 - 0.0021 17.1 0.6 0.0021 17.1 0.4 1.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EMR65654.1 - 0.014 14.4 0.9 0.033 13.2 0.5 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 EMR65654.1 - 0.066 13.6 4.8 2.3 8.6 1.4 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EMR65654.1 - 0.13 11.7 0.5 0.28 10.6 0.3 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EMR65654.1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EMR65654.1 - 0.17 11.6 2.5 0.32 10.7 0.4 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 EMR65654.1 - 0.27 10.0 4.8 0.37 9.6 2.9 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EMR65654.1 - 0.57 9.8 1.8 1.2 8.7 1.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EAF PF09816.4 EMR65656.1 - 2.2e-21 75.8 0.3 4.7e-21 74.8 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor TauD PF02668.11 EMR65657.1 - 1.6e-53 181.9 0.1 2.1e-53 181.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CBM_21 PF03370.8 EMR65658.1 - 1e-32 112.4 0.9 2.5e-32 111.2 0.0 2.1 3 0 0 3 3 3 1 Putative phosphatase regulatory subunit Pkinase PF00069.20 EMR65659.1 - 5.9e-25 87.8 0.0 3.4e-20 72.2 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR65659.1 - 3e-07 29.7 0.0 0.0019 17.3 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EMR65659.1 - 0.014 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Syja_N PF02383.13 EMR65660.1 - 1.6e-93 313.0 0.0 2.5e-93 312.3 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EMR65660.1 - 1.8e-30 104.6 0.0 3.8e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Inositol phosphatase DNA_pol_B_2 PF03175.8 EMR65660.1 - 0.22 10.1 0.1 0.33 9.5 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral p450 PF00067.17 EMR65661.1 - 7.8e-52 176.3 0.0 1.1e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CsbD PF05532.7 EMR65662.1 - 1.9e-15 56.2 24.1 7.1e-09 35.2 4.3 3.3 2 1 1 3 3 3 3 CsbD-like DUF3292 PF11696.3 EMR65662.1 - 0.003 15.5 1.6 0.0049 14.8 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) NSP2_assoc PF14758.1 EMR65662.1 - 0.023 14.8 2.2 0.027 14.6 1.2 1.4 1 1 0 1 1 1 0 Non-essential region of nsp2 of arterivirus polyprotein DUF3430 PF11912.3 EMR65663.1 - 0.0027 17.5 0.1 0.003 17.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Trypan_glycop_C PF10659.4 EMR65663.1 - 0.066 13.4 0.0 0.092 13.0 0.0 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain VanZ PF04892.7 EMR65663.1 - 0.071 13.0 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 VanZ like family NmrA PF05368.8 EMR65664.1 - 5.8e-09 35.5 0.0 4.6e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR65664.1 - 2.7e-07 30.7 0.0 5.2e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EMR65664.1 - 0.00014 21.9 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EMR65664.1 - 0.018 15.0 0.1 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 EMR65664.1 - 0.044 12.7 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase GARS_N PF02844.10 EMR65664.1 - 0.047 14.1 0.0 0.093 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain NAD_binding_7 PF13241.1 EMR65664.1 - 0.13 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding ZZ PF00569.12 EMR65665.1 - 8.8e-17 60.3 61.7 2e-05 24.0 5.4 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type PC4 PF02229.11 EMR65666.1 - 1.9e-20 71.8 0.0 3.4e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) CCP_MauG PF03150.9 EMR65667.1 - 0.021 15.1 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase AhpC-TSA_2 PF13911.1 EMR65669.1 - 4.6e-16 58.7 0.0 1.7e-15 56.9 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EMR65669.1 - 0.001 18.7 0.0 0.0027 17.3 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMR65669.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Redoxin Clat_adaptor_s PF01217.15 EMR65670.1 - 1.3e-51 174.0 1.2 1.5e-51 173.8 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CDC50 PF03381.10 EMR65671.1 - 6.2e-93 310.9 0.0 7.7e-93 310.6 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SET PF00856.23 EMR65672.1 - 4.7e-15 56.2 0.0 1e-14 55.1 0.0 1.6 1 1 0 1 1 1 1 SET domain Mucin PF01456.12 EMR65672.1 - 0.14 11.8 17.1 1.8 8.3 6.8 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3446 PF11928.3 EMR65672.1 - 0.23 11.6 8.5 7 6.9 2.7 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3446) AAA_12 PF13087.1 EMR65673.1 - 2.2e-59 200.1 0.0 4.1e-59 199.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.5 EMR65673.1 - 5.8e-57 191.5 0.0 7.8e-56 187.8 0.0 2.4 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.1 EMR65673.1 - 1.1e-55 188.7 1.2 1.9e-55 188.0 0.9 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMR65673.1 - 7.4e-14 51.2 0.1 1.8e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EMR65673.1 - 1.2e-12 47.8 0.1 6.3e-11 42.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EMR65673.1 - 2.3e-07 30.8 0.0 4.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EMR65673.1 - 0.0001 22.0 0.0 0.00024 20.8 0.0 1.7 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EMR65673.1 - 0.00026 20.5 0.1 1.4 8.3 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PIF1 PF05970.9 EMR65673.1 - 0.00086 18.3 0.0 0.25 10.2 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase DUF2075 PF09848.4 EMR65673.1 - 0.0016 17.4 0.9 0.0045 16.0 0.0 2.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EMR65673.1 - 0.0018 17.6 0.0 0.068 12.4 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EMR65673.1 - 0.0026 17.2 0.1 0.0053 16.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase KaiC PF06745.8 EMR65673.1 - 0.015 14.4 0.0 0.1 11.6 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.1 EMR65673.1 - 0.02 14.9 0.1 0.045 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.17 EMR65673.1 - 0.025 14.0 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EMR65673.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain UvrD_C_2 PF13538.1 EMR65673.1 - 0.12 12.5 0.0 0.39 10.8 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain T2SE PF00437.15 EMR65673.1 - 0.13 11.1 0.0 0.26 10.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 EMR65673.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EMR65673.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Asp PF00026.18 EMR65674.1 - 3.2e-68 230.3 2.5 4.2e-68 229.9 1.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMR65674.1 - 6.1e-10 39.2 0.0 3.5e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMR65674.1 - 4.5e-06 27.0 1.0 0.19 12.2 0.2 3.0 2 1 0 2 2 2 2 Aspartyl protease CMD PF02627.15 EMR65675.1 - 3.5e-11 42.8 1.0 9.8e-11 41.3 0.1 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family ATP-synt_C PF00137.16 EMR65676.1 - 6e-31 106.1 30.9 1.1e-18 66.8 8.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EMR65676.1 - 0.18 11.3 3.4 0.065 12.7 0.4 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A PT PF04886.7 EMR65677.1 - 0.0014 17.9 7.1 0.0014 17.9 4.9 6.1 3 2 1 4 4 4 3 PT repeat P68HR PF08061.6 EMR65677.1 - 0.0044 16.7 17.8 0.52 10.0 0.2 6.3 4 3 1 5 5 5 4 P68HR (NUC004) repeat Brix PF04427.13 EMR65678.1 - 1.5e-34 119.3 0.1 5.8e-34 117.4 0.1 1.7 1 1 0 1 1 1 1 Brix domain MFS_1 PF07690.11 EMR65679.1 - 1.1e-26 93.4 22.2 1e-21 77.0 5.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR65679.1 - 9.8e-07 27.5 10.3 9.8e-07 27.5 7.1 2.0 2 0 0 2 2 2 1 MFS/sugar transport protein DUF1673 PF07895.6 EMR65679.1 - 0.14 11.6 0.2 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) LacY_symp PF01306.14 EMR65679.1 - 0.37 9.2 11.4 0.61 8.5 0.1 2.2 2 0 0 2 2 2 0 LacY proton/sugar symporter Vps55 PF04133.9 EMR65679.1 - 0.82 9.4 5.5 0.13 12.0 0.5 2.1 2 1 0 2 2 2 0 Vacuolar protein sorting 55 Zip PF02535.17 EMR65680.1 - 0.15 11.0 0.7 0.18 10.7 0.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.2 EMR65680.1 - 0.85 7.2 4.2 1 6.9 2.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spt5_N PF11942.3 EMR65680.1 - 1 10.0 23.4 0.6 10.7 8.3 3.0 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Ycf1 PF05758.7 EMR65680.1 - 2.8 5.5 5.0 3.3 5.3 3.5 1.0 1 0 0 1 1 1 0 Ycf1 Maf1 PF09174.5 EMR65681.1 - 3e-56 190.1 0.0 4.9e-56 189.4 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator TPR_11 PF13414.1 EMR65682.1 - 4.5e-53 176.7 16.6 6.5e-13 48.1 0.0 6.4 5 1 1 6 6 6 6 TPR repeat TPR_2 PF07719.12 EMR65682.1 - 7.6e-40 131.6 16.7 5.2e-05 22.8 0.0 10.9 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.23 EMR65682.1 - 6.1e-39 130.0 17.6 2.1e-05 23.9 0.0 11.5 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 EMR65682.1 - 7.4e-29 99.7 13.9 5.5e-07 30.0 0.2 6.7 6 1 1 7 7 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 EMR65682.1 - 3e-25 87.9 22.2 3.3e-07 30.1 0.0 7.4 3 1 4 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 EMR65682.1 - 1e-21 75.2 6.0 0.00025 20.9 0.0 9.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMR65682.1 - 2.5e-16 58.6 16.6 0.025 15.1 0.5 9.2 5 3 5 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 EMR65682.1 - 6.7e-16 56.8 11.5 0.31 10.9 0.1 8.8 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.1 EMR65682.1 - 6.6e-15 53.6 14.7 0.012 15.3 0.0 8.7 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 EMR65682.1 - 1.7e-12 46.9 16.5 1.7e-05 24.5 0.5 6.4 4 2 2 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMR65682.1 - 4.7e-12 46.0 20.5 5.3e-05 23.4 0.3 6.6 6 1 2 8 8 7 4 Tetratricopeptide repeat Apc3 PF12895.2 EMR65682.1 - 4.5e-11 42.7 10.4 0.0017 18.4 0.1 6.0 2 2 5 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.2 EMR65682.1 - 6.2e-05 22.8 7.2 3.2 7.5 0.0 5.8 3 1 2 6 6 6 1 Domain of Unknown Function (DUF3856) MAS20 PF02064.10 EMR65682.1 - 9.4e-05 22.3 2.5 2.9 7.8 0.0 4.1 4 0 0 4 4 4 1 MAS20 protein import receptor TPR_6 PF13174.1 EMR65682.1 - 0.00014 22.0 20.5 3.4 8.3 0.0 8.6 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMR65682.1 - 0.00026 20.8 13.1 2.7 8.0 0.8 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EMR65682.1 - 0.00043 19.4 14.4 0.68 9.2 0.0 6.8 7 0 0 7 7 7 2 SHNi-TPR NARP1 PF12569.3 EMR65682.1 - 0.00045 19.1 20.5 0.023 13.4 0.3 5.3 3 1 3 6 6 6 2 NMDA receptor-regulated protein 1 BLVR PF06375.6 EMR65682.1 - 0.0014 18.5 2.0 0.0034 17.2 1.4 1.6 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) BTAD PF03704.12 EMR65682.1 - 0.083 13.1 8.9 1.9 8.7 0.0 4.5 3 2 0 3 3 3 0 Bacterial transcriptional activator domain Sel1 PF08238.7 EMR65682.1 - 0.089 13.4 4.1 2.7 8.7 0.2 4.0 3 0 0 3 3 3 0 Sel1 repeat TPR_20 PF14561.1 EMR65682.1 - 0.42 10.7 9.9 0.24 11.5 0.3 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMR65682.1 - 1.4 9.5 9.4 39 5.0 0.0 4.9 4 0 0 4 4 3 0 Tetratricopeptide repeat SNARE PF05739.14 EMR65683.1 - 8.9e-14 50.9 3.3 8.9e-14 50.9 2.3 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EMR65683.1 - 1.3e-09 38.1 2.5 2.2e-09 37.4 0.1 2.1 2 0 0 2 2 2 1 Syntaxin Rifin_STEVOR PF02009.11 EMR65683.1 - 0.0021 17.7 0.2 0.0029 17.2 0.1 1.3 1 0 0 1 1 1 1 Rifin/stevor family DUF912 PF06024.7 EMR65683.1 - 0.0093 16.0 0.5 0.026 14.5 0.4 1.8 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) GP41 PF00517.12 EMR65683.1 - 0.0099 15.4 0.7 0.65 9.5 0.3 2.4 2 0 0 2 2 2 1 Retroviral envelope protein Peptidase_S46 PF10459.4 EMR65683.1 - 0.045 12.1 7.7 0.06 11.7 5.4 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF1469 PF07332.6 EMR65683.1 - 0.12 12.1 2.9 0.27 10.9 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Tweety PF04906.8 EMR65683.1 - 0.15 10.4 2.8 0.079 11.3 0.6 1.5 2 0 0 2 2 2 0 Tweety Mito_fiss_reg PF05308.6 EMR65683.1 - 0.3 10.4 2.9 0.8 9.0 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator T2SF PF00482.18 EMR65683.1 - 0.3 11.0 2.1 0.5 10.2 0.2 2.2 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Fib_alpha PF08702.5 EMR65683.1 - 5.6 7.0 6.8 3.6 7.6 0.6 2.8 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family V-SNARE PF05008.10 EMR65683.1 - 6.7 6.9 7.6 9.3 6.4 0.2 3.4 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus SHNi-TPR PF10516.4 EMR65685.1 - 1.2e-14 53.2 0.3 1.2e-14 53.2 0.2 2.7 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.1 EMR65685.1 - 2.3e-10 40.2 8.4 2e-05 24.4 0.4 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMR65685.1 - 2.1e-06 27.2 9.9 5.8e-05 22.6 0.5 3.4 2 1 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 EMR65685.1 - 3.5e-06 27.5 4.4 4.5e-05 24.0 0.6 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EMR65685.1 - 4.8e-06 26.6 0.2 0.00092 19.3 0.1 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 EMR65685.1 - 0.0012 18.5 2.7 0.0012 18.5 1.9 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR65685.1 - 0.0021 18.3 0.5 0.0021 18.3 0.4 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMR65685.1 - 0.0034 17.1 14.1 0.06 13.2 1.2 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF3856 PF12968.2 EMR65685.1 - 0.0081 15.9 3.9 0.19 11.5 0.1 3.1 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_17 PF13431.1 EMR65685.1 - 0.014 15.5 1.2 4.3 7.7 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMR65685.1 - 0.1 12.5 2.3 0.16 11.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMR65685.1 - 0.26 11.1 5.1 1.9 8.4 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMR65685.1 - 0.72 10.6 6.8 3.5 8.5 0.4 3.9 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMR65685.1 - 1.1 8.9 8.6 0.5 10.0 0.8 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMR65685.1 - 3.9 7.4 8.6 15 5.6 1.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat PTCB-BRCT PF12738.2 EMR65686.1 - 1.4e-05 24.8 1.6 0.00013 21.7 1.1 2.2 1 1 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EMR65686.1 - 0.00021 21.3 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain MFS_1 PF07690.11 EMR65687.1 - 8.2e-26 90.5 18.1 4.6e-17 61.7 6.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily FUSC_2 PF13515.1 EMR65688.1 - 3.8e-26 91.4 6.5 3.8e-26 91.4 4.5 3.0 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.7 EMR65688.1 - 5.1e-09 35.1 11.9 1.1e-07 30.7 6.0 2.6 3 0 0 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.3 EMR65688.1 - 9.2e-08 31.1 12.5 0.0012 17.5 2.2 3.3 3 0 0 3 3 3 3 Aluminium activated malate transporter DUF2421 PF10334.4 EMR65688.1 - 1.1e-06 28.4 1.8 0.00033 20.3 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2421) DUF2422 PF10337.4 EMR65688.1 - 7.6e-05 21.6 0.8 7.6e-05 21.6 0.5 3.3 2 1 2 4 4 4 2 Protein of unknown function (DUF2422) FUSC-like PF12805.2 EMR65688.1 - 0.078 11.8 4.1 13 4.6 0.1 3.6 2 1 1 3 3 3 0 FUSC-like inner membrane protein yccS PS_pyruv_trans PF04230.8 EMR65688.1 - 0.19 11.4 0.1 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase Aldo_ket_red PF00248.16 EMR65689.1 - 9.6e-11 41.0 0.0 1.3e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Response_reg PF00072.19 EMR65690.1 - 7.9e-29 99.9 0.2 1.3e-28 99.2 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EMR65690.1 - 2.9e-13 49.5 0.4 8.3e-13 48.0 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3794 PF12673.2 EMR65690.1 - 0.089 12.9 0.2 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3794) Ribosomal_L7Ae PF01248.21 EMR65691.1 - 4.1e-27 93.5 0.1 4.9e-27 93.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EMR65691.1 - 0.00026 20.8 0.1 0.0003 20.6 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EMR65691.1 - 0.051 13.3 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Pectate_lyase PF03211.8 EMR65692.1 - 6.4e-76 254.5 2.5 7.8e-76 254.2 1.7 1.0 1 0 0 1 1 1 1 Pectate lyase Transketolase_N PF00456.16 EMR65693.1 - 1.3e-150 500.8 0.0 2e-150 500.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EMR65693.1 - 5e-47 159.6 0.0 1.1e-46 158.5 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EMR65693.1 - 2.1e-13 50.2 0.0 4.5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EMR65693.1 - 2.9e-05 23.1 0.0 7.1e-05 21.8 0.0 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase RRP7 PF12923.2 EMR65694.1 - 3.5e-35 120.8 10.5 3.5e-35 120.8 7.3 2.2 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Usp PF00582.21 EMR65694.1 - 0.64 10.2 6.9 1.3 9.2 0.3 2.4 2 1 0 2 2 2 0 Universal stress protein family Aminotran_5 PF00266.14 EMR65695.1 - 8.3e-95 317.6 0.0 1.1e-94 317.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMR65695.1 - 3.9e-07 29.5 0.0 5.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EMR65695.1 - 8.7e-05 21.7 0.0 0.00041 19.5 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family B12-binding PF02310.14 EMR65695.1 - 0.066 13.0 0.0 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain Pyridoxal_deC PF00282.14 EMR65695.1 - 0.079 11.3 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Pro-kuma_activ PF09286.6 EMR65696.1 - 1.9e-37 128.4 0.0 3.7e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EMR65696.1 - 6.5e-07 28.7 0.1 9.6e-07 28.2 0.1 1.2 1 0 0 1 1 1 1 Subtilase family COPIIcoated_ERV PF07970.7 EMR65698.1 - 1.7e-34 119.3 0.1 2.4e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EMR65698.1 - 5.2e-22 77.6 0.0 8.9e-22 76.8 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3115 PF11312.3 EMR65700.1 - 2.5e-77 259.8 0.0 1.4e-61 208.1 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF3115) Pex14_N PF04695.8 EMR65700.1 - 0.048 13.7 18.3 0.42 10.6 0.1 3.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Serglycin PF04360.7 EMR65700.1 - 0.67 9.6 3.8 0.35 10.6 0.3 2.1 2 0 0 2 2 2 0 Serglycin Fructosamin_kin PF03881.9 EMR65701.1 - 6.6e-14 51.5 0.0 2e-13 49.9 0.0 1.6 1 1 1 2 2 2 1 Fructosamine kinase APH PF01636.18 EMR65702.1 - 6e-07 29.4 4.3 0.00032 20.5 1.5 3.1 2 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMR65702.1 - 2.3e-06 26.8 0.0 0.0034 16.4 0.0 3.0 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EMR65702.1 - 3.3e-05 23.1 0.0 8e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR65702.1 - 0.0014 17.7 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EMR65702.1 - 0.02 14.2 0.0 3.1 7.0 0.0 2.4 2 0 0 2 2 2 0 RIO1 family A_deaminase PF00962.17 EMR65703.1 - 3.5e-42 144.4 0.0 6.1e-42 143.7 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase Btz PF09405.5 EMR65704.1 - 2e-20 73.1 1.5 2e-20 73.1 1.0 2.2 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Ebola_NP PF05505.7 EMR65704.1 - 0.3 9.1 2.7 0.34 8.9 1.9 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Gln-synt_C PF00120.19 EMR65705.1 - 7.4e-60 202.2 0.0 9.2e-60 201.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EMR65705.1 - 3.8e-18 64.8 0.0 7.8e-18 63.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Hydantoinase_B PF02538.9 EMR65706.1 - 5.4e-198 658.4 0.0 8.4e-191 634.7 0.0 2.1 2 0 0 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EMR65706.1 - 2.2e-93 312.5 0.8 4.8e-93 311.4 0.5 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EMR65706.1 - 1e-55 187.9 0.2 8e-54 181.7 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MOSC PF03473.12 EMR65707.1 - 1.1e-19 70.1 0.0 2.2e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.22 EMR65707.1 - 5e-11 42.1 1.0 1.3e-10 40.8 0.7 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 EMR65707.1 - 7.6e-09 36.1 0.3 6.4e-08 33.1 0.0 2.7 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain 3-alpha PF03475.9 EMR65707.1 - 0.0045 16.6 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 3-alpha domain NAD_binding_6 PF08030.7 EMR65707.1 - 0.043 13.7 0.0 6.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Rabaptin PF03528.10 EMR65708.1 - 0.13 12.1 0.2 0.35 10.7 0.1 1.7 1 1 0 1 1 1 0 Rabaptin PsbX PF06596.6 EMR65708.1 - 1.6 8.4 5.3 3.6 7.3 3.7 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) BAR PF03114.13 EMR65709.1 - 2.5e-64 216.9 6.7 3.1e-64 216.6 4.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EMR65709.1 - 3.9e-15 54.9 0.0 7.1e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMR65709.1 - 1.2e-14 53.5 0.0 2.1e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMR65709.1 - 7.2e-10 38.2 0.0 1.8e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain APG6 PF04111.7 EMR65709.1 - 0.33 9.9 7.7 0.42 9.6 2.5 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Topoisom_I_N PF02919.10 EMR65709.1 - 0.46 9.7 7.9 0.027 13.7 1.8 1.5 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment TMF_DNA_bd PF12329.3 EMR65709.1 - 8.2 6.3 11.5 0.31 10.8 3.6 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding p450 PF00067.17 EMR65710.1 - 2.3e-47 161.6 0.0 2.1e-46 158.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Yae1_N PF09811.4 EMR65711.1 - 8.6e-06 25.1 9.2 3.4e-05 23.2 6.4 1.9 1 1 0 1 1 1 1 Essential protein Yae1, N terminal HD PF01966.17 EMR65712.1 - 3.1e-08 33.6 0.1 6.2e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 HD domain NFRKB_winged PF14465.1 EMR65713.1 - 0.027 14.3 0.8 0.74 9.6 0.0 3.3 3 2 1 4 4 4 0 NFRKB Winged Helix-like DWNN PF08783.6 EMR65714.1 - 1.6e-29 101.6 0.1 2.9e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EMR65714.1 - 4.4e-05 22.8 5.1 0.00013 21.3 3.5 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EMR65714.1 - 0.0011 18.7 1.5 0.0011 18.7 1.0 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-RING_6 PF14835.1 EMR65714.1 - 0.0027 17.4 1.7 0.0048 16.6 1.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-CCHC_3 PF13917.1 EMR65714.1 - 0.016 14.8 0.4 0.045 13.5 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle FYVE_2 PF02318.11 EMR65714.1 - 0.02 14.7 1.5 0.02 14.7 1.0 1.9 2 0 0 2 2 1 0 FYVE-type zinc finger U-box PF04564.10 EMR65714.1 - 0.021 14.7 0.7 0.079 12.9 0.0 2.4 2 0 0 2 2 2 0 U-box domain zf-Nse PF11789.3 EMR65714.1 - 0.26 10.8 4.9 0.59 9.6 3.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 EMR65714.1 - 0.59 9.9 12.7 0.062 13.0 4.9 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EMR65714.1 - 1.3 8.7 9.5 2.7 7.7 6.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMR65714.1 - 1.5 8.7 9.3 4.3 7.3 6.4 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EMR65714.1 - 2.1 8.4 14.9 0.14 12.2 6.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RNase_T PF00929.19 EMR65716.1 - 2.8e-05 24.4 0.0 0.016 15.5 0.0 2.1 2 0 0 2 2 2 2 Exonuclease Abhydrolase_3 PF07859.8 EMR65717.1 - 1e-06 28.5 0.0 1.2e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Glyoxalase PF00903.20 EMR65718.1 - 1.6e-13 50.7 0.1 2.3e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMR65718.1 - 9.9e-11 42.2 0.0 1.6e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EMR65718.1 - 0.017 15.1 0.1 0.14 12.1 0.0 2.4 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 EMR65718.1 - 0.026 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 CppA N-terminal Amidohydro_2 PF04909.9 EMR65719.1 - 1.8e-20 73.6 0.0 3.6e-20 72.6 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase SUR7 PF06687.7 EMR65720.1 - 8.9e-24 84.2 10.6 1.2e-23 83.7 7.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EMR65720.1 - 0.39 10.5 12.6 0.49 10.2 8.7 1.1 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 UcrQ PF02939.11 EMR65721.1 - 2.1e-33 113.9 1.4 2.5e-33 113.7 1.0 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.20 EMR65722.1 - 6.1e-25 88.1 5.1 1.2e-24 87.2 3.5 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 EMR65722.1 - 0.0086 15.4 1.9 0.013 14.8 0.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2884) Prenylcys_lyase PF07156.9 EMR65722.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Prenylcysteine lyase ArsA_ATPase PF02374.10 EMR65723.1 - 4.7e-109 364.1 0.0 5.5e-109 363.8 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EMR65723.1 - 3.1e-15 56.0 0.1 7.6e-15 54.8 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EMR65723.1 - 6e-08 32.7 0.0 8.6e-06 25.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EMR65723.1 - 2e-06 27.1 0.2 4.4e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EMR65723.1 - 4e-05 23.1 0.0 0.0014 18.1 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 EMR65723.1 - 0.0071 16.0 0.0 0.023 14.4 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EMR65723.1 - 0.012 15.0 0.1 0.021 14.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMR65723.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein YhjQ PF06564.7 EMR65723.1 - 0.026 13.8 0.0 0.062 12.6 0.0 1.5 1 0 0 1 1 1 0 YhjQ protein MipZ PF09140.6 EMR65723.1 - 0.027 13.5 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ NB-ARC PF00931.17 EMR65723.1 - 0.085 11.6 0.1 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 EMR65723.1 - 0.13 11.1 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 EMR65723.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NAD_Gly3P_dh_N PF01210.18 EMR65725.1 - 1.1e-46 158.4 0.1 2.1e-46 157.4 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EMR65725.1 - 4.1e-41 140.1 0.4 6.1e-41 139.6 0.3 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus DUF2358 PF10184.4 EMR65725.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) AIG2_2 PF13772.1 EMR65726.1 - 4.2e-05 23.5 0.0 0.00043 20.3 0.0 2.4 3 0 0 3 3 3 1 AIG2-like family Acetyltransf_1 PF00583.19 EMR65727.1 - 1e-07 31.8 0.1 5.4e-07 29.5 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR65727.1 - 4.7e-06 26.6 0.3 0.00063 19.8 0.0 2.9 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR65727.1 - 0.00064 19.5 0.2 0.0082 15.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMR65727.1 - 0.00087 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EMR65727.1 - 0.0038 17.3 0.5 0.039 14.0 0.0 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain hDGE_amylase PF14701.1 EMR65728.1 - 2.8e-178 593.1 0.0 3.6e-178 592.7 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EMR65728.1 - 2.6e-114 381.8 0.0 4.1e-114 381.1 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EMR65728.1 - 4.9e-88 294.6 0.0 2.3e-87 292.4 0.0 2.0 2 0 0 2 2 2 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EMR65728.1 - 1.9e-27 94.9 0.0 4.5e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EMR65728.1 - 0.00044 19.7 0.0 0.99 8.7 0.0 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain adh_short PF00106.20 EMR65730.1 - 9.9e-21 74.3 0.2 1.3e-12 47.9 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EMR65730.1 - 3e-17 63.1 0.0 1.3e-14 54.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR65730.1 - 3.3e-05 23.6 0.1 0.017 14.8 0.0 2.3 1 1 1 2 2 2 2 KR domain DUF1776 PF08643.5 EMR65730.1 - 0.00069 18.8 0.0 0.00097 18.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EMR65731.1 - 3.2e-12 46.2 0.0 2.7e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR65731.1 - 3e-06 27.3 0.0 1.2e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EMR65731.1 - 0.025 14.8 0.0 0.16 12.2 0.0 2.4 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EMR65731.1 - 0.055 12.8 0.0 0.34 10.3 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR65731.1 - 0.15 10.9 0.0 12 4.6 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein p450 PF00067.17 EMR65732.1 - 5.1e-28 97.8 0.1 5.8e-28 97.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 XAP5 PF04921.9 EMR65733.1 - 3.2e-71 239.6 0.0 1.2e-70 237.8 0.0 2.0 1 1 0 1 1 1 1 XAP5, circadian clock regulator Cu_amine_oxid PF01179.15 EMR65735.1 - 6.9e-127 423.5 0.0 4.3e-126 420.9 0.0 1.9 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EMR65735.1 - 1.5e-07 31.4 0.0 3.2e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EMR65735.1 - 1.5e-07 31.3 0.0 3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain DAO PF01266.19 EMR65736.1 - 4.3e-46 157.4 1.1 4.8e-46 157.2 0.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR65736.1 - 0.00039 20.3 0.8 0.029 14.2 0.5 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR65736.1 - 0.0018 18.2 0.0 0.0047 16.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMR65736.1 - 0.0031 17.2 0.6 0.62 9.8 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EMR65736.1 - 0.007 16.6 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding HI0933_like PF03486.9 EMR65736.1 - 0.0085 14.6 0.7 0.039 12.4 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein TrkA_N PF02254.13 EMR65736.1 - 0.015 15.3 0.2 0.069 13.1 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.7 EMR65736.1 - 0.015 14.2 0.1 0.027 13.3 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EMR65736.1 - 0.045 12.3 5.8 0.5 8.9 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.11 EMR65736.1 - 0.062 12.7 1.1 0.15 11.4 0.7 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 EMR65736.1 - 0.071 13.5 1.8 0.1 12.9 0.4 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR65736.1 - 0.57 8.9 3.9 1.1 8.0 2.7 1.6 1 1 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EMR65736.1 - 1.1 8.0 5.2 0.93 8.2 1.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.11 EMR65737.1 - 1.7e-07 30.3 31.7 8e-06 24.8 18.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EMR65737.1 - 7.6e-06 25.4 8.7 7.6e-06 25.4 6.0 2.3 1 1 1 2 2 2 1 Ion channel regulatory protein UNC-93 MASE2 PF05230.6 EMR65737.1 - 0.33 10.9 3.5 0.93 9.5 2.0 2.2 1 1 0 1 1 1 0 MASE2 domain DUF4064 PF13273.1 EMR65737.1 - 4.9 7.3 9.8 2.9 8.0 3.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF4131 PF13567.1 EMR65737.1 - 4.9 6.5 10.8 0.32 10.3 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Trep_Strep PF09605.5 EMR65737.1 - 5.4 6.6 18.8 0.11 12.1 5.7 3.0 2 1 1 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Nucleoporin_FG PF13634.1 EMR65738.1 - 1.5e-12 47.7 90.7 5.9e-09 36.1 18.4 3.6 2 1 1 3 3 3 2 Nucleoporin FG repeat region Baculo_PEP_C PF04513.7 EMR65738.1 - 0.055 13.3 0.2 6.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fungal_trans PF04082.13 EMR65739.1 - 4.2e-11 42.2 0.0 7.6e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AFT PF08731.6 EMR65740.1 - 0.00021 21.4 1.8 0.00053 20.1 1.2 1.6 1 0 0 1 1 1 1 Transcription factor AFT GAS PF13851.1 EMR65740.1 - 0.00043 19.5 0.1 0.067 12.3 0.0 2.2 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding FAR1 PF03101.10 EMR65740.1 - 0.0011 19.4 1.9 0.002 18.6 1.3 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain Methyltransf_10 PF05971.7 EMR65741.1 - 1.3e-57 195.2 0.0 1.8e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 EMR65741.1 - 1.4e-07 31.5 0.0 2.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR65741.1 - 9.3e-07 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EMR65741.1 - 2e-05 25.1 0.0 4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMR65741.1 - 0.00026 20.2 0.0 0.00041 19.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EMR65741.1 - 0.003 17.1 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR65741.1 - 0.0078 16.6 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EMR65741.1 - 0.058 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 N6_Mtase PF02384.11 EMR65741.1 - 0.081 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase SOR_SNZ PF01680.12 EMR65743.1 - 2.7e-105 350.5 6.1 3.8e-105 350.0 4.2 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EMR65743.1 - 5.9e-08 32.0 10.1 5e-06 25.7 0.7 2.5 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EMR65743.1 - 6.1e-05 22.3 0.4 0.013 14.8 0.0 3.2 2 1 1 3 3 3 1 Histidine biosynthesis protein Dus PF01207.12 EMR65743.1 - 0.00083 18.2 0.1 0.52 9.0 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 EMR65743.1 - 0.0058 15.6 0.3 0.11 11.4 0.0 2.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 EMR65743.1 - 0.0089 15.1 0.3 0.026 13.5 0.0 1.9 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase NMO PF03060.10 EMR65743.1 - 1.3 8.0 9.4 0.077 12.1 0.5 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase Fip1 PF05182.8 EMR65744.1 - 5e-21 73.7 2.1 1.2e-20 72.4 1.5 1.6 1 0 0 1 1 1 1 Fip1 motif Sigma70_ner PF04546.8 EMR65744.1 - 7 6.2 10.1 14 5.1 7.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region GMC_oxred_C PF05199.8 EMR65746.1 - 5.4e-29 101.3 0.0 1e-28 100.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR65746.1 - 1.5e-19 70.3 0.0 2.2e-18 66.4 0.0 2.5 2 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 EMR65746.1 - 0.00033 20.6 0.0 0.027 14.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR65746.1 - 0.0034 16.3 0.1 0.02 13.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR65746.1 - 0.014 15.4 0.2 0.014 15.4 0.2 2.7 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMR65746.1 - 0.048 12.5 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Fig1 PF12351.3 EMR65747.1 - 4.9e-30 104.7 8.2 5.8e-30 104.5 5.7 1.0 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EMR65747.1 - 0.00018 21.1 6.4 0.00022 20.8 4.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EMR65747.1 - 0.00082 18.3 6.4 0.00088 18.2 4.4 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) Yip1 PF04893.12 EMR65747.1 - 0.031 13.7 11.0 0.043 13.3 7.6 1.2 1 0 0 1 1 1 0 Yip1 domain DUF202 PF02656.10 EMR65747.1 - 0.057 13.6 0.1 0.057 13.6 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Cation_ATPase_C PF00689.16 EMR65747.1 - 0.076 12.5 5.9 0.12 11.8 4.1 1.4 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF4131 PF13567.1 EMR65747.1 - 0.2 11.0 0.1 0.2 11.0 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) MpPF26 PF07666.6 EMR65747.1 - 0.39 10.6 10.0 1.2 9.0 4.5 2.1 2 0 0 2 2 2 0 M penetrans paralogue family 26 Tic20 PF09685.5 EMR65747.1 - 1 9.3 12.8 3.3e+02 1.2 8.8 2.1 1 1 0 1 1 1 0 Tic20-like protein PgaD PF13994.1 EMR65747.1 - 3.2 7.2 7.6 44 3.5 0.0 2.6 2 1 0 2 2 2 0 PgaD-like protein ABC2_membrane_3 PF12698.2 EMR65747.1 - 4.7 6.1 17.2 4.9 6.0 1.6 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein HMG_box PF00505.14 EMR65749.1 - 5.1e-25 87.5 0.8 7.1e-25 87.0 0.6 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMR65749.1 - 2.1e-18 66.4 1.3 3.4e-18 65.7 0.9 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EMR65749.1 - 0.00058 19.6 0.7 0.0011 18.7 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DEADboxA PF12343.3 EMR65749.1 - 0.23 11.7 4.6 7.5 6.8 3.2 2.2 1 1 0 1 1 1 0 Cold shock protein DEAD box A ADH_zinc_N PF00107.21 EMR65750.1 - 6.4e-29 100.1 1.5 1e-28 99.4 1.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR65750.1 - 5.5e-16 59.6 1.0 1.1e-15 58.5 0.1 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR65750.1 - 5.3e-13 48.6 0.0 1.6e-12 47.1 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EMR65750.1 - 0.00082 18.9 0.1 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EMR65750.1 - 0.0023 17.8 0.0 0.0063 16.5 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.1 EMR65750.1 - 0.04 13.9 0.2 0.061 13.3 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding ELFV_dehydrog PF00208.16 EMR65750.1 - 0.041 13.4 0.1 0.082 12.4 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CENP-H PF05837.7 EMR65751.1 - 1.2e-24 86.4 0.5 1.5e-24 86.1 0.4 1.1 1 0 0 1 1 1 1 Centromere protein H (CENP-H) DUF2216 PF10226.4 EMR65751.1 - 0.0027 17.2 0.8 0.0032 16.9 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved proteins (DUF2216) Myosin_tail_1 PF01576.14 EMR65751.1 - 0.022 12.5 3.4 0.027 12.2 2.3 1.0 1 0 0 1 1 1 0 Myosin tail Trans_reg_C PF00486.23 EMR65751.1 - 0.09 12.7 0.5 0.5 10.3 0.1 2.1 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal DUF3829 PF12889.2 EMR65751.1 - 0.098 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Tmemb_18A PF09771.4 EMR65751.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 188 APG6 PF04111.7 EMR65751.1 - 0.16 11.0 0.8 0.19 10.7 0.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3708 PF12501.3 EMR65751.1 - 0.26 11.1 2.6 0.31 10.8 1.8 1.1 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter HALZ PF02183.13 EMR65751.1 - 0.45 10.2 3.2 1.8 8.3 0.3 2.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper ATG11 PF10377.4 EMR65752.1 - 7e-38 129.4 0.0 7e-38 129.4 0.0 3.4 4 0 0 4 4 4 1 Autophagy-related protein 11 Tropomyosin PF00261.15 EMR65752.1 - 0.0015 17.7 8.7 0.0015 17.7 6.0 6.5 4 1 3 7 7 7 3 Tropomyosin AA_permease PF00324.16 EMR65753.1 - 2.7e-125 418.4 41.8 3.1e-125 418.2 29.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR65753.1 - 2e-30 105.7 47.7 2.6e-30 105.3 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease WSC PF01822.14 EMR65754.1 - 1.2e-12 47.5 7.9 1.2e-12 47.5 5.5 1.7 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 EMR65754.1 - 4.2e-07 29.1 2.6 4.2e-07 29.1 1.8 2.2 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 EMR65754.1 - 0.0092 15.5 0.6 0.015 14.9 0.4 1.3 1 0 0 1 1 1 1 Podoplanin DUF4366 PF14283.1 EMR65754.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Med3 PF11593.3 EMR65754.1 - 0.03 13.5 1.2 0.039 13.1 0.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4448 PF14610.1 EMR65754.1 - 0.03 13.7 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1517 PF07466.6 EMR65754.1 - 0.037 13.0 1.8 0.055 12.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Adeno_E3_CR2 PF02439.10 EMR65754.1 - 0.053 13.0 1.3 0.13 11.8 0.9 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rax2 PF12768.2 EMR65754.1 - 0.12 11.6 0.2 0.53 9.4 0.0 1.9 2 0 0 2 2 2 0 Cortical protein marker for cell polarity DUF202 PF02656.10 EMR65754.1 - 0.13 12.5 0.3 0.32 11.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) MAGE_N PF12440.3 EMR65754.1 - 3.2 8.1 13.2 0.5 10.6 5.4 2.3 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal Cu_bind_like PF02298.12 EMR65755.1 - 0.0018 18.0 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 2 Plastocyanin-like domain Copper-bind PF00127.15 EMR65755.1 - 0.057 13.6 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Glyco_hydro_47 PF01532.15 EMR65756.1 - 9.1e-174 578.3 0.0 1.3e-173 577.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CFEM PF05730.6 EMR65757.1 - 1.9e-05 24.3 2.4 1.9e-05 24.3 1.7 3.1 2 0 0 2 2 2 1 CFEM domain Mitofilin PF09731.4 EMR65757.1 - 0.52 8.9 6.5 0.69 8.4 4.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Sigma70_r2 PF04542.9 EMR65758.1 - 0.063 12.8 0.4 0.18 11.4 0.2 1.9 2 0 0 2 2 2 0 Sigma-70 region 2 DUF4449 PF14613.1 EMR65759.1 - 0.012 15.4 0.0 0.077 12.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) DUF4208 PF13907.1 EMR65759.1 - 0.19 11.9 4.6 0.93 9.7 0.3 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) CHORD PF04968.7 EMR65760.1 - 9.8 6.5 9.7 2 8.7 0.3 2.9 1 1 1 2 2 2 0 CHORD Abhydro_lipase PF04083.11 EMR65761.1 - 1.7e-22 78.5 0.1 3.5e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EMR65761.1 - 3.8e-19 69.1 0.1 1.1e-18 67.6 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR65761.1 - 1.1e-06 28.6 0.0 2e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR65761.1 - 0.00032 20.4 0.0 0.0019 17.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EMR65761.1 - 0.00069 19.1 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Pet191_N PF10203.4 EMR65762.1 - 3.7e-28 97.3 3.7 4.9e-28 96.9 2.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Clusterin PF01093.12 EMR65762.1 - 0.57 8.9 2.9 0.71 8.6 2.0 1.1 1 0 0 1 1 1 0 Clusterin Cmc1 PF08583.5 EMR65762.1 - 3.1 7.6 6.6 4.4 7.1 0.3 2.6 2 1 0 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like eIF-5a PF01287.15 EMR65765.1 - 3.1e-05 23.8 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Myosin_head PF00063.16 EMR65766.1 - 4.3e-246 818.2 0.0 4.3e-246 818.2 0.0 2.5 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EMR65766.1 - 1.6e-22 79.1 108.1 5.5e-22 77.3 52.6 6.2 2 2 3 5 5 5 4 Myosin tail Filament PF00038.16 EMR65766.1 - 0.0025 17.3 32.0 0.0025 17.3 22.2 10.2 1 1 7 9 9 9 5 Intermediate filament protein Ank_5 PF13857.1 EMR65767.1 - 1e-05 25.5 0.0 2.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMR65767.1 - 0.04 14.2 0.0 0.073 13.4 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Wound_ind PF08186.6 EMR65767.1 - 1.3 8.9 10.9 0.043 13.7 1.4 3.0 2 1 1 3 3 3 0 Wound-inducible basic protein family Peptidase_C1_2 PF03051.10 EMR65768.1 - 1.5e-149 498.3 0.0 1.7e-149 498.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EMR65768.1 - 1e-07 32.0 0.3 0.00026 20.9 0.4 2.5 2 1 0 2 2 2 2 Papain family cysteine protease MFS_1 PF07690.11 EMR65769.1 - 4.2e-15 55.3 42.9 1.8e-08 33.5 7.3 3.1 1 1 1 3 3 3 3 Major Facilitator Superfamily DUF2304 PF10066.4 EMR65769.1 - 0.22 11.3 1.8 0.97 9.2 1.2 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) GWT1 PF06423.7 EMR65769.1 - 4.7 7.3 7.6 0.43 10.6 0.8 2.3 3 0 0 3 3 3 0 GWT1 Viral_P18 PF04521.8 EMR65770.1 - 0.074 12.4 2.8 0.56 9.6 0.1 2.4 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein zf-C3H1 PF10650.4 EMR65770.1 - 0.21 11.1 1.4 0.31 10.5 1.0 1.3 1 0 0 1 1 1 0 Putative zinc-finger domain Tropomyosin_1 PF12718.2 EMR65770.1 - 0.25 11.1 7.9 0.15 11.9 2.1 2.1 2 0 0 2 2 2 0 Tropomyosin like SlyX PF04102.7 EMR65770.1 - 1.6 9.1 7.1 17 5.8 0.3 2.8 2 0 0 2 2 2 0 SlyX HET PF06985.6 EMR65771.1 - 9.5e-11 42.0 0.0 1.8e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3441 PF11923.3 EMR65772.1 - 1e-34 118.4 0.1 4.3e-34 116.4 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EMR65772.1 - 3.6e-34 118.0 7.9 3.6e-34 118.0 5.5 1.7 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EMR65772.1 - 6.3e-23 80.4 0.0 1.4e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Peptidase_A4 PF01828.12 EMR65774.1 - 5.5e-28 97.4 2.6 7.6e-28 97.0 1.8 1.2 1 0 0 1 1 1 1 Peptidase A4 family p450 PF00067.17 EMR65777.1 - 2.2e-45 155.0 0.0 3.1e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SR-25 PF10500.4 EMR65778.1 - 0.0044 16.5 0.9 0.0052 16.2 0.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CobA_CobO_BtuR PF02572.10 EMR65778.1 - 0.011 15.3 0.2 0.013 15.1 0.1 1.0 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Nop53 PF07767.6 EMR65778.1 - 0.016 14.2 0.5 0.019 13.9 0.3 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ADIP PF11559.3 EMR65778.1 - 0.037 13.9 3.8 0.049 13.5 2.6 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Mre11_DNA_bind PF04152.9 EMR65778.1 - 0.055 13.3 1.0 0.071 12.9 0.7 1.1 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain DUF4661 PF15576.1 EMR65778.1 - 0.099 12.2 0.2 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF2464 PF10240.4 EMR65778.1 - 0.15 11.3 0.4 0.17 11.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) Dmrt1 PF12374.3 EMR65778.1 - 2 8.8 7.9 3 8.2 5.5 1.3 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 Zn_clus PF00172.13 EMR65779.1 - 6.9e-08 32.2 8.4 1.4e-07 31.2 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGAP PF00620.22 EMR65781.1 - 5.4e-47 159.2 0.0 1.3e-45 154.7 0.0 2.6 1 1 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EMR65781.1 - 3.4e-15 56.0 2.8 1.7e-14 53.7 0.5 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain PmrD PF11183.3 EMR65781.1 - 0.097 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD p450 PF00067.17 EMR65782.1 - 1.1e-30 106.5 0.0 1.5e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Med12 PF09497.5 EMR65784.1 - 2.1e-19 69.2 0.1 7.9e-19 67.4 0.1 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 SLAC1 PF03595.12 EMR65785.1 - 5.2e-85 285.0 36.6 5.9e-85 284.8 25.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF1469 PF07332.6 EMR65785.1 - 1.3 8.7 13.1 0.25 11.0 0.5 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1469) DUF605 PF04652.11 EMR65786.1 - 0.088 12.1 6.1 0.092 12.1 4.2 1.0 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 EMR65786.1 - 0.47 10.1 5.5 0.48 10.1 3.8 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.3 EMR65786.1 - 1.2 7.7 19.8 1.5 7.4 13.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.5 EMR65786.1 - 1.3 7.1 21.7 1.5 6.9 15.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Gag_spuma PF03276.9 EMR65786.1 - 1.3 7.2 14.2 1.4 7.1 9.8 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DUF2201_N PF13203.1 EMR65786.1 - 1.5 7.9 8.0 1.5 7.8 5.5 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4175 PF13779.1 EMR65786.1 - 3.3 5.3 15.4 3.3 5.3 10.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Baculo_PP31 PF05311.6 EMR65786.1 - 4.9 6.3 6.7 6.3 5.9 4.7 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) NUDE_C PF04880.8 EMR65787.1 - 2.6e-18 66.9 4.9 2.6e-18 66.9 3.4 1.9 2 0 0 2 2 1 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 EMR65787.1 - 1.6e-05 23.5 31.1 2.1e-05 23.2 21.6 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light IncA PF04156.9 EMR65787.1 - 0.00057 19.5 32.8 0.033 13.7 7.4 2.1 1 1 1 2 2 2 2 IncA protein DUF904 PF06005.7 EMR65787.1 - 0.0019 18.4 30.8 0.0025 18.0 4.9 3.6 1 1 2 3 3 3 2 Protein of unknown function (DUF904) ERM PF00769.14 EMR65787.1 - 0.013 15.0 31.1 0.05 13.1 7.1 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ADIP PF11559.3 EMR65787.1 - 0.022 14.6 9.6 0.022 14.6 6.7 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 EMR65787.1 - 0.046 13.5 34.6 0.69 9.7 10.1 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EMR65787.1 - 0.1 12.0 30.8 0.44 9.9 21.3 2.1 1 1 0 1 1 1 0 Intermediate filament protein ATG16 PF08614.6 EMR65787.1 - 0.2 11.4 27.6 1.9 8.2 9.3 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Perilipin PF03036.11 EMR65787.1 - 0.31 9.8 9.6 0.41 9.4 6.7 1.1 1 0 0 1 1 1 0 Perilipin family TPR_MLP1_2 PF07926.7 EMR65787.1 - 0.4 10.4 32.4 2.9 7.6 13.6 3.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 EMR65787.1 - 0.99 9.2 36.6 3.7 7.3 16.6 3.1 1 1 1 2 2 2 0 Tropomyosin like DUF972 PF06156.8 EMR65787.1 - 1 9.7 23.2 0.81 10.0 3.9 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 EMR65787.1 - 1.1 7.6 25.6 2.5 6.4 17.8 1.4 1 1 0 1 1 1 0 AAA domain TBPIP PF07106.8 EMR65787.1 - 1.4 8.4 25.2 0.58 9.6 7.7 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF664 PF04978.7 EMR65787.1 - 1.7 8.8 7.8 0.74 10.0 1.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF664) Prefoldin_2 PF01920.15 EMR65787.1 - 2.6 7.8 32.3 0.69 9.7 5.3 4.6 1 1 4 5 5 5 0 Prefoldin subunit WXG100 PF06013.7 EMR65787.1 - 3.1 7.8 12.3 4.3 7.3 2.6 3.8 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DMPK_coil PF08826.5 EMR65787.1 - 4.3 7.3 27.4 0.12 12.2 2.1 3.5 3 0 0 3 3 3 0 DMPK coiled coil domain like RTBV_P46 PF06216.6 EMR65787.1 - 4.6 5.9 13.2 2.2 7.0 1.3 2.3 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein Peptidase_S8 PF00082.17 EMR65789.1 - 1.1e-44 152.7 0.0 2.3e-44 151.6 0.0 1.6 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EMR65789.1 - 3e-16 59.8 0.1 6.6e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EMR65789.1 - 2e-08 33.8 0.0 6.2e-08 32.2 0.0 1.9 1 0 0 1 1 1 1 PA domain Inhibitor_I9 PF05922.11 EMR65789.1 - 0.00071 20.0 0.1 0.0015 19.0 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 FlgD_ig PF13860.1 EMR65789.1 - 0.028 14.1 0.1 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 FlgD Ig-like domain Methyltransf_2 PF00891.13 EMR65790.1 - 2e-33 115.6 0.0 3.1e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EMR65790.1 - 0.0045 16.7 0.0 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_23 PF13489.1 EMR65790.1 - 0.11 12.2 0.0 0.38 10.4 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain GLTT PF01744.15 EMR65791.1 - 0.44 10.0 5.8 0.84 9.1 4.0 1.4 1 0 0 1 1 1 0 GLTT repeat (6 copies) Sugar_tr PF00083.19 EMR65792.1 - 1.6e-47 162.1 31.3 2e-26 92.5 14.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR65792.1 - 4.5e-19 68.3 38.7 3.1e-15 55.7 7.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR65792.1 - 0.0023 16.2 6.5 0.0033 15.6 4.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EMR65792.1 - 0.0041 16.8 0.2 0.019 14.7 0.2 2.1 1 0 0 1 1 1 1 MFS_1 like family Gate PF07670.9 EMR65792.1 - 0.055 13.3 7.9 0.028 14.3 2.9 2.4 2 1 0 2 2 2 0 Nucleoside recognition LOH1CR12 PF10158.4 EMR65793.1 - 0.002 17.9 0.5 0.0031 17.2 0.3 1.2 1 0 0 1 1 1 1 Tumour suppressor protein DUF972 PF06156.8 EMR65793.1 - 0.055 13.8 0.6 0.095 13.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TSC22 PF01166.13 EMR65793.1 - 0.078 12.9 0.2 0.078 12.9 0.1 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Leu_zip PF15294.1 EMR65793.1 - 0.2 10.7 5.3 0.28 10.2 3.7 1.1 1 0 0 1 1 1 0 Leucine zipper MFS_1 PF07690.11 EMR65794.1 - 1.1e-53 182.2 36.7 1.1e-53 182.2 25.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR65794.1 - 7.4e-14 51.1 20.0 7.4e-14 51.1 13.9 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMR65794.1 - 1.5e-07 29.9 2.9 2.9e-07 29.0 2.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EMR65794.1 - 1.3e-05 23.5 5.1 2e-05 22.9 3.5 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector 60KD_IMP PF02096.15 EMR65794.1 - 1.4 8.5 5.2 0.43 10.2 0.3 2.5 2 1 0 2 2 2 0 60Kd inner membrane protein SR-25 PF10500.4 EMR65796.1 - 0.00025 20.5 15.6 0.00028 20.4 10.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Lectin_N PF03954.9 EMR65796.1 - 0.19 11.1 1.5 0.24 10.8 1.0 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain KdpC PF02669.10 EMR65796.1 - 0.37 10.4 1.8 0.42 10.2 1.3 1.1 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Nop53 PF07767.6 EMR65796.1 - 0.53 9.2 10.8 0.6 9.0 7.5 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4407 PF14362.1 EMR65796.1 - 1.1 8.1 6.1 1.3 7.9 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tmemb_cc2 PF10267.4 EMR65796.1 - 1.1 7.7 9.3 1.3 7.5 6.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Period_C PF12114.3 EMR65796.1 - 2.1 7.8 15.4 2.6 7.6 10.6 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Neur_chan_memb PF02932.11 EMR65796.1 - 2.9 7.6 7.5 3.3 7.5 5.2 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.4 EMR65796.1 - 4.3 5.4 12.5 5 5.2 8.7 1.0 1 0 0 1 1 1 0 Transmembrane protein SGT1 PF07093.6 EMR65796.1 - 9.6 4.4 11.9 12 4.1 8.3 1.0 1 0 0 1 1 1 0 SGT1 protein NESP55 PF06390.7 EMR65797.1 - 0.03 13.6 0.8 0.038 13.3 0.5 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Toxin_66 PF15544.1 EMR65797.1 - 0.28 10.4 1.5 0.38 9.9 1.0 1.3 1 1 0 1 1 1 0 Putative toxin 66 AA_permease PF00324.16 EMR65798.1 - 1.7e-98 330.0 42.8 2.1e-98 329.7 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR65798.1 - 3.1e-20 72.1 44.4 3.8e-20 71.8 30.8 1.0 1 0 0 1 1 1 1 Amino acid permease Myb_DNA-bind_6 PF13921.1 EMR65799.1 - 3.5e-16 59.0 3.1 1.1e-10 41.4 0.1 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMR65799.1 - 2.3e-12 46.7 6.2 9e-05 22.4 0.0 4.2 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EMR65799.1 - 8.2e-05 22.6 7.3 0.00049 20.1 0.4 3.3 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain Abhydrolase_1 PF00561.15 EMR65801.1 - 1.5e-09 37.8 0.0 1.4e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR65801.1 - 7.9e-09 35.7 0.1 1.7e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Drc1-Sld2 PF11719.3 EMR65803.1 - 1.6e-56 192.2 16.6 1.8e-56 192.0 11.5 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein TPR_12 PF13424.1 EMR65805.1 - 2.8e-12 46.3 1.0 2.1e-05 24.3 0.5 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMR65805.1 - 1.1e-08 34.6 0.9 0.0013 18.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMR65805.1 - 2e-06 27.1 1.2 0.0034 17.0 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMR65805.1 - 8e-06 25.4 0.3 0.21 11.2 0.0 3.1 2 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 EMR65805.1 - 1.4e-05 24.4 1.3 0.088 12.6 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMR65805.1 - 2e-05 24.1 4.2 0.049 13.5 0.1 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMR65805.1 - 0.00013 21.4 4.3 0.17 11.5 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMR65805.1 - 0.0032 17.9 4.3 1.1 10.0 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMR65805.1 - 0.028 15.1 5.6 3.7 8.3 1.5 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMR65805.1 - 0.066 13.6 0.1 76 4.0 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L24e PF01246.15 EMR65805.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L24e Glyco_hydro_28 PF00295.12 EMR65806.1 - 1.3e-41 142.6 1.0 1.8e-41 142.2 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 ECH PF00378.15 EMR65807.1 - 6e-41 140.1 0.2 9.9e-32 109.9 0.8 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family DUF3439 PF11921.3 EMR65807.1 - 1.7 8.3 7.0 2.8 7.7 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) K_oxygenase PF13434.1 EMR65808.1 - 9.9e-11 41.1 0.0 4.3e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EMR65808.1 - 6.6e-10 39.3 0.0 2.7e-07 30.8 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR65808.1 - 5.3e-06 25.5 0.6 0.42 9.4 0.0 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR65808.1 - 1.1e-05 25.4 0.0 0.018 14.9 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR65808.1 - 0.0002 21.1 0.1 0.06 13.1 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EMR65808.1 - 0.0064 15.4 0.0 0.26 10.1 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EMR65808.1 - 0.018 15.4 3.5 0.75 10.2 0.1 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR65808.1 - 0.022 13.2 0.1 2 6.7 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 EMR65808.1 - 0.04 12.9 3.0 0.23 10.4 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain Nucleoplasmin PF03066.10 EMR65808.1 - 0.094 12.2 1.0 0.16 11.4 0.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin Thi4 PF01946.12 EMR65808.1 - 0.11 11.6 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 EMR65808.1 - 0.23 11.5 0.8 2.3 8.2 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF4611 PF15387.1 EMR65808.1 - 1.6 8.9 5.6 3.7 7.7 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 EMR65808.1 - 5.9 7.2 8.6 8.9 6.7 4.8 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Abhydrolase_3 PF07859.8 EMR65809.1 - 1.4e-41 142.4 0.3 2.6e-41 141.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR65809.1 - 8.4e-07 28.8 0.1 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EMR65809.1 - 4.4e-06 25.6 0.0 7.6e-05 21.6 0.0 2.2 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EMR65809.1 - 0.0026 17.0 0.0 0.0097 15.1 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMR65809.1 - 0.0036 17.1 3.1 0.0077 16.1 2.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMR65809.1 - 0.013 14.8 0.0 0.013 14.8 0.0 1.8 3 0 0 3 3 3 0 Dienelactone hydrolase family Eno-Rase_NADH_b PF12242.3 EMR65809.1 - 0.021 14.5 0.0 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AXE1 PF05448.7 EMR65809.1 - 0.11 10.9 0.1 0.21 10.0 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) HTH_Tnp_Tc3_2 PF01498.13 EMR65809.1 - 0.29 11.2 2.5 3.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Transposase DUF2196 PF09962.4 EMR65810.1 - 1.3e-21 76.1 2.8 2.1e-21 75.4 1.9 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) HAS-barrel PF09378.5 EMR65810.1 - 0.034 14.0 0.1 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 HAS barrel domain TOBE_2 PF08402.5 EMR65810.1 - 0.055 13.4 0.4 0.17 11.9 0.2 1.9 2 0 0 2 2 2 0 TOBE domain zf-H2C2_5 PF13909.1 EMR65810.1 - 0.065 13.4 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Mac PF12464.3 EMR65811.1 - 8.8e-23 80.0 0.0 1.4e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 EMR65811.1 - 1.9e-13 49.2 8.8 1.9e-12 46.1 2.4 3.2 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMR65811.1 - 2e-13 49.6 6.6 3.1e-13 49.0 1.3 2.8 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Subtilosin_A PF11420.3 EMR65811.1 - 0.02 14.9 0.1 0.058 13.4 0.1 1.8 1 0 0 1 1 1 0 Bacteriocin subtilosin A PWI PF01480.12 EMR65813.1 - 6.2e-10 39.0 1.4 1e-09 38.3 0.3 1.9 2 0 0 2 2 2 1 PWI domain Rif1_N PF12231.3 EMR65813.1 - 0.047 12.6 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal Ribosomal_S21 PF01165.15 EMR65814.1 - 2.9e-13 49.0 4.5 6.8e-13 47.8 3.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S21 TPT PF03151.11 EMR65815.1 - 6.6e-31 107.0 18.6 1.2e-30 106.1 6.7 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EMR65815.1 - 7.8e-05 21.7 3.0 7.8e-05 21.7 2.1 2.2 2 0 0 2 2 2 1 UAA transporter family DUF914 PF06027.7 EMR65815.1 - 0.073 11.8 12.2 0.29 9.9 8.5 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EMR65815.1 - 1.6 8.7 23.4 0.082 12.9 4.7 3.0 3 0 0 3 3 3 0 EamA-like transporter family p450 PF00067.17 EMR65817.1 - 2.2e-09 36.3 0.0 2.4e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 EMR65819.1 - 0.0029 16.2 1.7 0.01 14.4 0.2 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Rnk_N PF14760.1 EMR65819.1 - 0.093 12.8 0.9 0.18 11.8 0.6 1.5 1 0 0 1 1 1 0 Rnk N-terminus Las1 PF04031.8 EMR65820.1 - 7.8e-61 204.2 0.3 1.3e-60 203.4 0.2 1.4 1 0 0 1 1 1 1 Las1-like Lactamase_B PF00753.22 EMR65820.1 - 3.6e-23 82.2 3.4 1.3e-22 80.4 2.4 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMR65820.1 - 2.6e-05 23.8 0.1 4.7e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Cation_efflux PF01545.16 EMR65821.1 - 1.1e-25 90.2 14.6 5.8e-21 74.7 8.7 2.1 2 0 0 2 2 2 2 Cation efflux family Sec10 PF07393.6 EMR65822.1 - 2.4e-158 528.5 0.0 2.9e-158 528.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 U79_P34 PF03064.11 EMR65822.1 - 3.7 6.9 7.7 0.058 12.9 0.2 1.6 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Abhydrolase_1 PF00561.15 EMR65823.1 - 4.8e-11 42.6 0.0 7.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR65823.1 - 3.4e-09 36.9 0.0 5.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR65823.1 - 0.00013 21.7 0.1 0.0004 20.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Alpha-amylase_C PF02806.13 EMR65823.1 - 0.066 13.3 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain MSP1_C PF07462.6 EMR65824.1 - 0.28 9.5 0.4 0.47 8.7 0.2 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Mid1 PF12929.2 EMR65825.1 - 6.4e-119 397.4 0.2 8.1e-119 397.1 0.1 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EMR65825.1 - 0.0042 17.4 1.9 0.055 13.8 0.3 2.4 2 0 0 2 2 2 1 Fz domain Cohesin_load PF10345.4 EMR65826.1 - 2.6e-89 300.1 2.1 3.1e-89 299.8 1.5 1.0 1 0 0 1 1 1 1 Cohesin loading factor RAMP4 PF06624.7 EMR65827.1 - 3.6e-08 32.8 0.0 4.7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF4199 PF13858.1 EMR65827.1 - 0.069 13.0 0.0 0.071 13.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF1206 PF06724.6 EMR65827.1 - 0.082 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) SMAP PF15477.1 EMR65828.1 - 5.9e-18 64.9 4.5 5.9e-18 64.9 3.1 6.2 5 3 0 5 5 5 1 Small acidic protein family SpoIIE PF07228.7 EMR65829.1 - 9.2e-11 41.7 0.0 7.5e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EMR65829.1 - 6.1e-09 35.5 0.3 1.1e-08 34.6 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EMR65829.1 - 2.2e-08 33.8 0.1 0.0058 16.0 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C GPI-anchored PF10342.4 EMR65830.1 - 4.1e-06 27.1 0.0 5.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Fer2_3 PF13085.1 EMR65831.1 - 1.7e-32 111.5 0.0 2.8e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.1 EMR65831.1 - 4.1e-09 36.3 4.3 4.1e-09 36.3 3.0 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 EMR65831.1 - 5.5e-09 36.2 6.2 5.5e-09 36.2 4.3 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EMR65831.1 - 1.3e-05 25.5 1.4 1.3e-05 25.5 1.0 2.7 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EMR65831.1 - 7.4e-05 22.9 4.0 0.02 15.1 0.4 3.2 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 EMR65831.1 - 9.2e-05 22.7 2.8 9.2e-05 22.7 2.0 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EMR65831.1 - 0.00021 20.9 4.4 0.00021 20.9 3.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EMR65831.1 - 0.0014 18.3 3.0 0.0026 17.4 0.2 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 EMR65831.1 - 0.25 11.9 0.2 0.25 11.9 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain AMP-binding PF00501.23 EMR65833.1 - 2.6e-48 164.4 0.1 2.6e-35 121.6 0.0 2.1 1 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EMR65833.1 - 3.1e-14 53.6 0.1 8.2e-14 52.3 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Arginase PF00491.16 EMR65834.1 - 2.1e-82 276.5 0.5 2.8e-82 276.1 0.4 1.1 1 0 0 1 1 1 1 Arginase family Abhydrolase_6 PF12697.2 EMR65835.1 - 2.4e-05 24.3 2.6 0.00021 21.2 1.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR65835.1 - 3.6e-05 23.5 0.1 6.3e-05 22.7 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMR65835.1 - 0.00017 21.2 2.0 0.0042 16.6 1.4 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EMR65835.1 - 0.054 13.7 0.2 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Thioesterase domain MobB PF03205.9 EMR65835.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TauD PF02668.11 EMR65836.1 - 1.3e-49 169.2 0.5 1.5e-49 169.0 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EMR65836.1 - 0.00066 20.1 0.2 0.34 11.4 0.1 2.5 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily Glyco_hydro_28 PF00295.12 EMR65837.1 - 2e-12 46.6 1.5 3.6e-09 36.0 0.0 2.4 2 1 0 2 2 2 2 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 EMR65837.1 - 6.8e-12 45.9 6.5 3.7e-11 43.5 3.7 2.6 1 1 1 2 2 2 1 Pectate lyase superfamily protein Beta_helix PF13229.1 EMR65837.1 - 0.014 15.1 4.1 2 8.1 1.2 2.8 2 1 0 2 2 2 0 Right handed beta helix region p450 PF00067.17 EMR65838.1 - 2.2e-21 75.9 0.0 5.5e-21 74.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_62 PF03664.8 EMR65839.1 - 7.5e-145 481.0 9.4 8.8e-145 480.8 6.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Aminotran_5 PF00266.14 EMR65840.1 - 3.8e-09 35.7 0.0 1.1e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EMR65840.1 - 0.0039 16.2 0.0 0.0052 15.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Asp PF00026.18 EMR65842.1 - 7.9e-54 183.0 0.0 9.7e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMR65842.1 - 5.5e-09 36.1 0.0 2.5e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMR65842.1 - 0.0086 16.5 0.6 0.45 11.0 0.0 2.8 3 0 0 3 3 3 1 Aspartyl protease OPT PF03169.10 EMR65843.1 - 1.3e-72 245.1 42.0 3.4e-59 200.8 19.6 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein NmrA PF05368.8 EMR65844.1 - 3.8e-16 59.0 0.0 4.7e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR65844.1 - 3e-15 56.7 1.5 4.7e-15 56.0 1.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EMR65844.1 - 4.2e-07 30.3 0.9 1.3e-06 28.7 0.1 2.0 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EMR65844.1 - 2.6e-05 24.1 0.0 0.00012 21.9 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 EMR65844.1 - 0.00018 21.8 1.7 0.0021 18.4 0.4 2.6 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EMR65844.1 - 0.0061 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_4 PF07993.7 EMR65844.1 - 0.012 14.5 0.0 0.03 13.2 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein Epimerase PF01370.16 EMR65844.1 - 0.013 14.9 0.0 0.11 11.9 0.0 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EMR65844.1 - 0.021 14.9 0.1 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EMR65844.1 - 0.12 11.5 0.1 0.34 10.0 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EMR65844.1 - 0.14 10.8 0.0 0.25 10.0 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMR65844.1 - 0.26 11.2 3.8 0.27 11.1 0.9 2.2 2 1 0 2 2 2 0 short chain dehydrogenase NAD_binding_8 PF13450.1 EMR65845.1 - 1.6e-08 34.4 0.6 3.4e-08 33.4 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR65845.1 - 9.2e-06 24.7 4.6 1.7e-05 23.8 2.5 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMR65845.1 - 5.7e-05 22.3 3.8 0.0014 17.7 2.6 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMR65845.1 - 5.9e-05 23.0 0.1 0.00012 21.9 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR65845.1 - 7.1e-05 23.1 0.8 0.00017 21.9 0.6 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR65845.1 - 0.0012 17.8 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EMR65845.1 - 0.0035 16.4 0.0 0.0053 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR65845.1 - 0.0049 15.7 4.0 0.02 13.7 2.9 1.8 1 1 1 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 EMR65845.1 - 0.013 14.5 0.2 0.28 10.1 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.18 EMR65845.1 - 0.034 13.8 0.5 0.055 13.2 0.3 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 EMR65845.1 - 0.036 12.9 2.1 0.052 12.4 1.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Rossmann-like PF10727.4 EMR65845.1 - 0.052 13.2 0.2 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 Rossmann-like domain Lactamase_B_2 PF12706.2 EMR65845.1 - 0.093 12.2 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain NAD_binding_2 PF03446.10 EMR65845.1 - 0.12 12.1 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.9 EMR65845.1 - 0.23 9.8 2.3 0.34 9.3 1.6 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 EMR65845.1 - 0.46 10.5 3.6 0.33 10.9 0.9 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EMR65845.1 - 1.8 8.2 6.9 0.13 11.8 1.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 EMR65846.1 - 4.9e-33 114.2 6.6 7e-28 97.5 0.0 3.3 3 1 1 4 4 4 2 KR domain adh_short PF00106.20 EMR65846.1 - 8.1e-23 81.1 3.8 5.5e-18 65.4 0.0 3.0 2 1 1 3 3 2 2 short chain dehydrogenase ADH_zinc_N PF00107.21 EMR65846.1 - 2.2e-22 78.9 0.0 6.4e-22 77.4 0.0 1.8 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMR65846.1 - 3e-17 62.8 0.0 1.1e-16 61.0 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EMR65846.1 - 3.2e-14 53.9 0.0 1.6e-13 51.6 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EMR65846.1 - 4e-12 46.1 0.0 1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR65846.1 - 1.4e-11 44.2 0.0 4.4e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR65846.1 - 2.3e-08 34.3 0.0 9.6e-08 32.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR65846.1 - 2.9e-08 34.2 0.0 1.3e-07 32.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EMR65846.1 - 4.3e-07 29.6 0.2 8.3e-06 25.5 0.1 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EMR65846.1 - 2e-05 24.7 0.0 5.6e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site NodS PF05401.6 EMR65846.1 - 0.00025 20.5 0.0 0.00052 19.4 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 EMR65846.1 - 0.00036 19.7 0.0 0.0013 17.8 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EMR65846.1 - 0.00094 18.6 0.0 0.0025 17.2 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_28 PF02636.12 EMR65846.1 - 0.042 13.2 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 EMR65846.1 - 0.066 13.2 0.0 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain APH PF01636.18 EMR65848.1 - 4e-18 66.0 0.0 8.1e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMR65848.1 - 0.0037 16.8 0.1 0.0067 16.0 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EMR65848.1 - 0.0043 16.4 0.3 0.17 11.2 0.1 2.3 2 0 0 2 2 2 1 RIO1 family EcKinase PF02958.15 EMR65848.1 - 0.011 14.8 0.0 0.024 13.7 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase Fructosamin_kin PF03881.9 EMR65848.1 - 0.06 12.3 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Fructosamine kinase MFS_1 PF07690.11 EMR65849.1 - 1.7e-09 36.9 9.4 2e-09 36.6 6.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR65849.1 - 1.8e-05 23.4 9.5 3.2e-05 22.6 6.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EMR65849.1 - 0.00062 18.0 0.6 0.00076 17.7 0.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MRAP PF15183.1 EMR65849.1 - 0.052 13.1 0.2 0.094 12.3 0.1 1.5 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Glycos_transf_1 PF00534.15 EMR65849.1 - 0.078 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 SspH PF08141.7 EMR65849.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Small acid-soluble spore protein H family PX PF00787.19 EMR65850.1 - 2.1e-17 62.9 0.0 3.6e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 PX domain F-box PF00646.28 EMR65851.1 - 2.8e-11 42.7 2.8 7.6e-11 41.3 1.6 2.0 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.2 EMR65851.1 - 4.1e-11 42.4 2.7 8.8e-11 41.3 1.9 1.6 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EMR65851.1 - 2.9e-08 33.2 8.9 0.0023 17.7 0.0 4.1 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 EMR65851.1 - 0.15 10.2 3.1 0.57 8.2 0.0 2.9 4 0 0 4 4 4 0 Nucleoporin Nup120/160 FAD-oxidase_C PF02913.14 EMR65852.1 - 3e-41 141.3 1.6 9.7e-41 139.7 1.1 1.6 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain Ribosomal_L18e PF00828.14 EMR65853.1 - 2.5e-16 60.2 0.1 5.6e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Trp_halogenase PF04820.9 EMR65853.1 - 0.00051 18.7 0.5 0.75 8.3 0.1 3.3 2 1 0 3 3 3 3 Tryptophan halogenase Sec62 PF03839.11 EMR65855.1 - 0.59 9.5 10.3 1.1 8.6 7.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 MIP-T3 PF10243.4 EMR65855.1 - 1.3 7.3 21.7 1.4 7.2 15.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Med19 PF10278.4 EMR65855.1 - 1.4 8.5 17.7 0.038 13.6 7.7 1.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 GST_C PF00043.20 EMR65856.1 - 3.1e-08 33.5 0.0 4.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMR65856.1 - 0.00024 20.9 0.1 0.00041 20.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMR65856.1 - 0.00076 19.6 0.0 0.0022 18.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMR65856.1 - 0.0058 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.11 EMR65857.1 - 5.6e-15 54.9 19.0 5.6e-15 54.9 13.1 2.7 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF2206 PF09971.4 EMR65857.1 - 0.26 10.0 2.3 0.47 9.2 1.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF1183 PF06682.7 EMR65859.1 - 0.046 13.3 0.1 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Amidoligase_2 PF12224.3 EMR65860.1 - 3.1e-05 23.7 0.0 0.044 13.3 0.0 2.9 2 1 0 2 2 2 2 Putative amidoligase enzyme Trehalase PF01204.13 EMR65861.1 - 2.5e-119 399.2 0.0 7.1e-118 394.4 0.0 2.1 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.9 EMR65861.1 - 3.4e-05 22.7 0.0 5.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase WD40 PF00400.27 EMR65862.1 - 1.1e-17 63.1 6.0 6.9e-07 28.9 0.0 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat SnoaL_2 PF12680.2 EMR65863.1 - 0.00021 21.6 0.0 0.00026 21.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EMR65863.1 - 0.048 13.8 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Ank_2 PF12796.2 EMR65864.1 - 3.1e-52 174.8 0.0 1.3e-16 60.6 0.0 8.6 3 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EMR65864.1 - 8.2e-48 157.9 6.4 4.3e-06 26.2 0.0 13.4 15 0 0 15 15 15 7 Ankyrin repeat Ank_5 PF13857.1 EMR65864.1 - 2.8e-37 125.9 2.2 0.00013 22.1 0.0 10.6 11 0 0 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR65864.1 - 7.6e-37 121.6 2.7 0.00039 20.4 0.0 12.4 14 0 0 14 14 14 6 Ankyrin repeat Ank_4 PF13637.1 EMR65864.1 - 3.3e-29 100.7 4.0 1.6e-06 28.4 0.0 11.1 11 1 1 12 12 12 5 Ankyrin repeats (many copies) Acetyltransf_3 PF13302.1 EMR65865.1 - 8.4e-32 110.2 0.0 1e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMR65865.1 - 8.4e-08 32.3 0.0 9.7e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR65865.1 - 1.1e-07 31.8 0.2 1.7e-07 31.1 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EMR65865.1 - 1.5e-05 24.8 0.0 2.9e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_transf_17 PF04724.8 EMR65866.1 - 4.3e-50 170.7 0.2 5.9e-50 170.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 STT3 PF02516.9 EMR65867.1 - 1.3e-126 423.3 41.0 8.7e-126 420.7 28.4 2.0 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Sel1 PF08238.7 EMR65869.1 - 5.9e-17 61.7 5.4 0.0007 20.1 0.1 4.4 4 0 0 4 4 4 4 Sel1 repeat ATP-synt_E PF05680.7 EMR65870.1 - 3.2e-24 84.6 0.1 3.5e-24 84.5 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain Drf_GBD PF06371.8 EMR65870.1 - 0.019 14.3 0.2 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain COPIIcoated_ERV PF07970.7 EMR65871.1 - 2e-73 246.7 0.2 4.1e-71 239.1 0.1 2.1 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EMR65871.1 - 8.7e-35 118.5 0.0 2.7e-34 117.0 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Beta_elim_lyase PF01212.16 EMR65872.1 - 1.2e-65 221.5 0.0 1.8e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EMR65872.1 - 2.7e-05 23.3 0.0 3.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMR65872.1 - 0.00034 19.0 0.0 0.00061 18.1 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EMR65872.1 - 0.011 14.7 0.1 0.028 13.4 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family NAD_binding_10 PF13460.1 EMR65873.1 - 9.3e-05 22.5 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding DXP_reductoisom PF02670.11 EMR65873.1 - 0.023 15.2 0.0 0.037 14.5 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Saccharop_dh PF03435.13 EMR65873.1 - 0.078 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EMR65873.1 - 0.081 11.8 0.0 0.35 9.7 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein CENP-L PF13092.1 EMR65874.1 - 2e-45 154.4 0.0 6.5e-45 152.8 0.0 1.8 2 1 0 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 DUF4588 PF15251.1 EMR65874.1 - 0.073 13.0 5.6 1.3 8.9 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4588) Ank_2 PF12796.2 EMR65875.1 - 3e-14 53.1 0.2 2.5e-05 24.5 0.0 3.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMR65875.1 - 4.5e-14 52.4 1.5 3.9e-07 30.4 0.1 3.8 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EMR65875.1 - 3.5e-11 42.3 1.6 6.3e-05 22.5 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EMR65875.1 - 2.3e-10 40.3 0.1 0.00067 19.8 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR65875.1 - 2.8e-10 39.3 0.1 0.0023 18.0 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EMR65875.1 - 0.0013 18.3 0.9 0.0013 18.3 0.6 2.6 2 1 0 2 2 2 1 KilA-N domain SKG6 PF08693.5 EMR65875.1 - 0.21 10.9 1.3 0.48 9.7 0.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3166 PF11365.3 EMR65875.1 - 0.49 10.8 4.4 0.68 10.4 0.2 3.2 2 2 0 3 3 3 0 Protein of unknown function (DUF3166) Fez1 PF06818.10 EMR65875.1 - 7.7 6.4 13.9 24 4.8 9.6 1.8 1 1 0 1 1 1 0 Fez1 Rbsn PF11464.3 EMR65876.1 - 0.00024 20.5 1.0 0.00051 19.5 0.2 2.0 2 0 0 2 2 2 1 Rabenosyn Rab binding domain Seryl_tRNA_N PF02403.17 EMR65876.1 - 0.0033 17.4 2.0 0.0039 17.1 0.1 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain CotJB PF12652.2 EMR65876.1 - 0.032 14.3 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 CotJB protein SpaB_C PF14028.1 EMR65876.1 - 0.21 11.1 4.4 0.059 12.9 0.9 1.6 2 0 0 2 2 2 0 SpaB C-terminal domain Pol_alpha_B_N PF08418.5 EMR65876.1 - 0.38 10.2 6.6 0.64 9.5 4.6 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal TMF_TATA_bd PF12325.3 EMR65876.1 - 2.1 8.1 7.3 1.1 9.0 2.7 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 EMR65876.1 - 2.8 8.3 4.8 50 4.3 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Acetyltransf_1 PF00583.19 EMR65877.1 - 4.8e-15 55.3 0.1 7.1e-15 54.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMR65877.1 - 4.7e-08 32.6 0.0 7.7e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EMR65877.1 - 7.8e-08 32.3 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR65877.1 - 1.5e-05 25.0 0.0 2.2e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMR65877.1 - 0.00011 22.3 0.0 0.00018 21.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMR65877.1 - 0.0044 16.9 0.0 0.016 15.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4349 PF14257.1 EMR65877.1 - 0.013 14.7 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Acetyltransf_9 PF13527.1 EMR65877.1 - 0.023 14.5 0.0 0.1 12.4 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EMR65877.1 - 0.085 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAD_binding_7 PF13241.1 EMR65878.1 - 4.5e-29 100.7 0.0 9.5e-29 99.6 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EMR65878.1 - 4.3e-23 80.3 0.0 6.8e-23 79.7 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EMR65878.1 - 2e-14 52.2 0.4 3.5e-14 51.4 0.3 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.1 EMR65878.1 - 0.0066 16.5 0.1 0.018 15.0 0.0 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Ead_Ea22 PF13935.1 EMR65878.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein Cuticle_3 PF11018.3 EMR65879.1 - 1.3 9.1 26.6 1.6 8.8 18.5 1.2 1 0 0 1 1 1 0 Pupal cuticle protein C1 p450 PF00067.17 EMR65880.1 - 4.3e-51 173.8 0.0 5.4e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.26 EMR65881.1 - 2.6e-11 43.4 0.0 7.8e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain MFS_1 PF07690.11 EMR65882.1 - 2.3e-29 102.2 30.8 2.3e-29 102.2 21.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EMR65883.1 - 1.5e-24 86.3 81.4 4.1e-17 61.9 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclin PF08613.6 EMR65885.1 - 3.5e-38 131.3 3.7 2.2e-22 80.0 0.1 2.5 2 1 1 3 3 3 2 Cyclin RNA_pol_3_Rpc31 PF11705.3 EMR65885.1 - 0.26 11.1 6.8 0.4 10.5 4.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4484 PF14831.1 EMR65885.1 - 3.8 7.5 6.0 7.2 6.6 1.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4484) DUF1175 PF06672.6 EMR65886.1 - 0.1 11.8 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) Peptidase_M19 PF01244.16 EMR65887.1 - 1.3e-103 346.2 0.1 1.6e-103 346.0 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) SIS PF01380.17 EMR65887.1 - 0.086 12.4 0.0 2 8.0 0.0 2.3 1 1 1 2 2 2 0 SIS domain Amidase PF01425.16 EMR65888.1 - 4.7e-16 58.6 0.0 7.4e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Amidase Peptidase_S8 PF00082.17 EMR65889.1 - 4.5e-46 157.2 22.8 6.3e-46 156.7 15.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMR65889.1 - 3.2e-09 37.2 0.0 7e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Proteasome PF00227.21 EMR65890.1 - 1e-45 155.3 0.4 1.2e-45 155.1 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit MFS_1 PF07690.11 EMR65891.1 - 3.4e-12 45.7 19.9 5.5e-09 35.1 1.9 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR65891.1 - 1.1e-06 27.5 2.7 1.1e-06 27.5 1.8 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EMR65891.1 - 0.015 13.7 0.4 0.015 13.7 0.2 2.7 1 1 2 3 3 3 0 MFS/sugar transport protein DUF4131 PF13567.1 EMR65891.1 - 0.37 10.1 3.0 0.68 9.3 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Evr1_Alr PF04777.8 EMR65892.1 - 2.4e-27 94.6 0.1 3.4e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Toxin-deaminase PF14424.1 EMR65892.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases C2 PF00168.25 EMR65893.1 - 6.4e-10 38.7 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain p450 PF00067.17 EMR65894.1 - 2.7e-48 164.6 0.0 3.3e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3425 PF11905.3 EMR65895.1 - 1.2e-30 106.1 0.1 1.8e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) HeLo PF14479.1 EMR65896.1 - 4.5e-06 26.5 0.7 0.012 15.4 0.0 3.0 2 1 1 3 3 3 2 Prion-inhibition and propagation adh_short PF00106.20 EMR65897.1 - 4e-19 69.1 0.0 5.8e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR65897.1 - 4.1e-09 36.3 0.1 6.6e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR65897.1 - 4.5e-06 26.6 0.0 7.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR65897.1 - 1.4e-05 24.6 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR65897.1 - 0.012 15.6 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding TIR-like PF10137.4 EMR65897.1 - 0.064 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain tRNA-synt_1d PF00750.14 EMR65898.1 - 5.6e-81 272.1 7.7 2.4e-80 270.0 5.3 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EMR65898.1 - 9.3e-28 96.5 0.1 1.9e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EMR65898.1 - 0.0075 16.7 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain DUF4473 PF14747.1 EMR65898.1 - 0.52 10.5 4.6 0.21 11.8 0.8 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) Herpes_capsid PF06112.6 EMR65900.1 - 3.1 7.8 6.8 4.9 7.1 4.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ferric_reduct PF01794.14 EMR65901.1 - 6.6e-17 61.7 13.2 6.6e-17 61.7 9.2 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EMR65901.1 - 2.9e-16 59.7 0.2 4.3e-16 59.2 0.2 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMR65901.1 - 9.2e-14 51.1 0.0 1.8e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain DAGK_cat PF00781.19 EMR65901.1 - 0.097 12.1 0.3 1.1 8.6 0.1 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain DUF788 PF05620.6 EMR65901.1 - 1.7 8.5 5.1 0.37 10.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF788) DUF4405 PF14358.1 EMR65901.1 - 6.8 6.9 12.8 12 6.1 2.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) p450 PF00067.17 EMR65902.1 - 1.5e-55 188.5 0.0 2.2e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RINGv PF12906.2 EMR65903.1 - 4e-16 58.7 9.3 6.8e-16 58.0 6.4 1.4 1 0 0 1 1 1 1 RING-variant domain zf-Apc11 PF12861.2 EMR65903.1 - 0.073 12.9 1.9 0.17 11.7 1.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EMR65903.1 - 0.1 12.4 8.4 0.18 11.6 5.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 EMR65903.1 - 6 6.5 6.5 11 5.7 4.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EMR65903.1 - 8.7 6.4 6.7 19 5.3 4.7 1.6 1 0 0 1 1 1 0 RING-like domain DUF3328 PF11807.3 EMR65904.1 - 8.9e-41 139.9 2.2 1.3e-40 139.3 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) 4HBT_3 PF13622.1 EMR65905.1 - 5.4e-18 65.6 6.7 2e-17 63.7 4.6 1.7 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMR65905.1 - 7.3e-12 45.0 0.0 3.5e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 Acyl-CoA thioesterase p450 PF00067.17 EMR65907.1 - 3.4e-10 39.0 0.0 3.8e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ODC_AZ PF02100.12 EMR65907.1 - 0.066 12.7 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Ornithine decarboxylase antizyme Esterase_phd PF10503.4 EMR65908.1 - 3.2e-25 88.6 0.7 4.9e-25 88.0 0.5 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EMR65908.1 - 2.9e-09 36.4 0.6 4.5e-09 35.8 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMR65908.1 - 2e-06 27.6 0.1 3.4e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR65908.1 - 8.9e-06 25.7 0.1 1.9e-05 24.6 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EMR65908.1 - 0.0037 16.0 0.7 0.0052 15.5 0.1 1.6 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S10 PF00450.17 EMR65908.1 - 0.0041 16.3 0.2 0.0066 15.6 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_3 PF07859.8 EMR65908.1 - 0.0045 16.5 0.1 0.0071 15.9 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EMR65908.1 - 0.0065 16.0 0.6 0.018 14.6 0.4 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glycos_transf_1 PF00534.15 EMR65909.1 - 2.1e-36 124.9 0.0 3e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMR65909.1 - 4e-18 65.8 0.0 7.4e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMR65909.1 - 3.5e-12 46.7 0.1 9.6e-12 45.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EMR65909.1 - 2.6e-11 43.6 0.0 5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EMR65909.1 - 9e-06 25.5 0.0 0.00033 20.4 0.0 2.6 2 1 0 2 2 2 1 Glycosyltransferase Family 4 NAD_binding_4 PF07993.7 EMR65910.1 - 2.4e-12 46.3 0.0 3.4e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EMR65911.1 - 2.7e-87 292.8 0.0 1.5e-83 280.5 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EMR65911.1 - 2.8e-56 190.5 0.0 2.6e-34 118.4 0.0 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EMR65911.1 - 2.4e-28 98.1 0.6 8.2e-15 54.8 0.0 3.6 3 0 0 3 3 3 2 Phosphopantetheine attachment site PknH_C PF14032.1 EMR65911.1 - 0.0016 18.0 1.1 0.0032 17.0 0.8 1.5 1 0 0 1 1 1 1 PknH-like extracellular domain Inositol_P PF00459.20 EMR65912.1 - 3.6e-50 170.7 0.1 1.5e-49 168.7 0.1 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family Abhydrolase_6 PF12697.2 EMR65913.1 - 2.9e-24 86.2 0.6 4.9e-24 85.4 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR65913.1 - 8.1e-15 55.0 0.1 1.2e-13 51.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR65913.1 - 2e-08 34.0 0.0 5.3e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EMR65913.1 - 0.0032 16.0 0.0 0.0055 15.2 0.0 1.4 1 0 0 1 1 1 1 Ndr family ISN1 PF06437.6 EMR65913.1 - 0.11 11.1 0.0 0.44 9.1 0.0 1.9 3 0 0 3 3 3 0 IMP-specific 5'-nucleotidase Fungal_trans PF04082.13 EMR65914.1 - 1.2e-17 63.6 0.3 2.5e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.17 EMR65915.1 - 1.7e-14 54.3 0.0 2.7e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Clr5 PF14420.1 EMR65916.1 - 1.3e-20 73.0 0.7 2.6e-20 72.0 0.5 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_16 PF13432.1 EMR65916.1 - 0.21 12.2 4.0 2.2 9.0 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF718 PF05336.8 EMR65917.1 - 0.025 14.3 2.8 0.041 13.6 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF718) DUF722 PF05263.6 EMR65917.1 - 0.055 13.5 2.1 0.13 12.3 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Chordopox_L2 PF05803.7 EMR65917.1 - 2.1 8.0 4.9 2.9 7.5 0.1 2.7 2 1 0 2 2 2 0 Chordopoxvirus L2 protein FAD_binding_3 PF01494.14 EMR65918.1 - 2.6e-21 76.0 0.0 4.4e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR65918.1 - 1.9e-05 23.7 0.0 0.0054 15.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR65918.1 - 0.003 17.5 0.0 0.0067 16.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMR65918.1 - 0.006 16.9 0.0 0.45 10.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR65918.1 - 0.0095 15.7 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EMR65918.1 - 0.02 13.5 0.0 4.2 5.8 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Sugar_tr PF00083.19 EMR65919.1 - 1.3e-43 149.1 5.9 1.6e-43 148.9 4.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR65919.1 - 3.6e-09 35.8 10.5 4.4e-09 35.5 7.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily AAA PF00004.24 EMR65920.1 - 2.1e-08 34.4 0.0 5.4e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cu_amine_oxid PF01179.15 EMR65921.1 - 1.6e-171 570.5 0.0 2e-171 570.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EMR65921.1 - 1e-16 60.7 0.1 2.2e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EMR65921.1 - 4.3e-10 39.5 0.0 8.2e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain HgmA PF04209.8 EMR65922.1 - 2.1e-169 563.4 0.0 2.4e-169 563.2 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase MFS_1 PF07690.11 EMR65923.1 - 5.9e-28 97.5 8.3 7.1e-28 97.3 5.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_Mycoplasma PF07672.8 EMR65923.1 - 0.037 13.1 0.2 0.037 13.1 0.2 2.0 2 2 0 2 2 2 0 Mycoplasma MFS transporter DUF3094 PF11293.3 EMR65923.1 - 0.29 10.6 1.6 7.9 6.0 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3094) 4HBT PF03061.17 EMR65924.1 - 1.9e-07 31.0 0.0 3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Pyr_redox_3 PF13738.1 EMR65925.1 - 5.4e-19 69.0 0.1 2e-12 47.6 0.0 2.9 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR65925.1 - 1.6e-12 47.2 0.0 3.5e-09 36.5 0.0 3.0 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EMR65925.1 - 4.7e-10 38.2 0.0 4e-07 28.6 0.0 2.8 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like DAO PF01266.19 EMR65925.1 - 1.5e-08 33.9 1.1 0.00012 21.1 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 EMR65925.1 - 5.3e-08 32.2 0.2 5.6e-05 22.3 0.0 3.0 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.9 EMR65925.1 - 5.2e-07 29.7 0.0 0.022 14.6 0.1 3.3 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR65925.1 - 6.7e-06 25.2 0.1 0.0003 19.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EMR65925.1 - 9.4e-06 25.9 0.0 0.013 15.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EMR65925.1 - 8.4e-05 22.6 0.0 0.07 13.2 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EMR65925.1 - 0.00011 21.2 0.7 0.00032 19.6 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EMR65925.1 - 0.00022 21.0 0.7 0.66 9.7 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EMR65925.1 - 0.00035 19.6 0.3 0.015 14.2 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 EMR65925.1 - 0.0023 17.7 0.0 0.005 16.5 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 EMR65925.1 - 0.0071 15.2 4.4 0.021 13.6 0.1 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A ApbA PF02558.11 EMR65925.1 - 0.009 15.4 0.2 0.044 13.2 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EMR65925.1 - 0.011 14.2 0.8 0.029 12.8 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EMR65925.1 - 0.011 15.3 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 EMR65925.1 - 0.031 13.3 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EMR65925.1 - 0.047 13.9 0.0 0.35 11.1 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 EMR65925.1 - 0.055 12.0 1.4 4.5 5.7 0.1 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Strep_67kDa_ant PF06100.6 EMR65925.1 - 0.16 10.2 0.0 0.33 9.2 0.0 1.4 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Oxysterol_BP PF01237.13 EMR65926.1 - 1.5e-53 181.5 0.0 5.3e-43 146.8 0.0 2.2 2 0 0 2 2 2 2 Oxysterol-binding protein FAM110_C PF14160.1 EMR65928.1 - 0.017 16.0 1.2 0.035 15.0 0.8 1.5 1 0 0 1 1 1 0 Centrosome-associated C terminus Pex14_N PF04695.8 EMR65928.1 - 0.078 13.0 11.1 0.03 14.3 2.9 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_S49_N PF08496.5 EMR65928.1 - 0.85 9.3 3.6 1.4 8.6 2.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TFIIA PF03153.8 EMR65928.1 - 2.2 8.1 17.5 0.69 9.7 5.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 EMR65928.1 - 9.6 5.8 16.2 0.49 10.0 5.4 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) zf-C2H2_3 PF13878.1 EMR65929.1 - 0.014 14.9 3.6 0.037 13.5 0.1 2.8 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Sugar_tr PF00083.19 EMR65930.1 - 5e-31 107.7 22.6 1.4e-29 102.9 15.7 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR65930.1 - 7.7e-29 100.4 23.4 7.7e-29 100.4 16.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.11 EMR65930.1 - 0.027 13.2 3.7 0.034 12.8 1.1 1.9 1 1 1 2 2 2 0 BT1 family Transp_cyt_pur PF02133.10 EMR65931.1 - 5.4e-84 282.2 31.0 6.6e-84 281.9 21.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transaldolase PF00923.14 EMR65932.1 - 3.3e-48 164.2 0.1 3.8e-48 164.0 0.1 1.0 1 0 0 1 1 1 1 Transaldolase Xan_ur_permease PF00860.15 EMR65933.1 - 3.2e-64 216.8 36.0 7.4e-63 212.3 24.9 2.0 1 1 0 1 1 1 1 Permease family WD40 PF00400.27 EMR65934.1 - 3.7e-08 32.9 4.8 0.00012 21.8 0.1 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ_2 PF13360.1 EMR65934.1 - 0.017 14.6 0.2 0.1 12.0 0.1 2.2 1 1 0 1 1 1 0 PQQ-like domain Apc4_WD40 PF12894.2 EMR65934.1 - 0.048 13.1 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain CobT PF06213.7 EMR65934.1 - 0.9 8.6 7.1 1.3 8.0 5.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 EMR65934.1 - 1.1 7.0 7.5 1.5 6.6 5.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EMR65934.1 - 3.4 5.5 12.4 5 5.0 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Oxidored_molyb PF00174.14 EMR65935.1 - 5.8e-52 175.5 0.0 8.2e-52 175.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EMR65935.1 - 3.1e-25 88.3 5.0 5.8e-17 61.5 0.4 3.5 5 0 0 5 5 5 2 Mo-co oxidoreductase dimerisation domain Sugar_tr PF00083.19 EMR65937.1 - 3.7e-119 398.2 27.5 4.6e-119 397.9 19.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR65937.1 - 9.8e-27 93.5 36.2 2.9e-21 75.5 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR65937.1 - 2e-06 26.4 34.0 0.00058 18.3 9.6 3.4 3 1 0 3 3 3 2 MFS/sugar transport protein Lysis_S PF04971.7 EMR65937.1 - 0.011 15.4 0.2 0.042 13.5 0.1 2.0 1 0 0 1 1 1 0 Lysis protein S UbiA PF01040.13 EMR65939.1 - 4.4e-30 104.7 20.5 5.6e-30 104.4 14.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Mito_carr PF00153.22 EMR65939.1 - 0.017 14.8 0.2 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial carrier protein mRNA_triPase PF02940.10 EMR65940.1 - 8.5e-48 162.9 0.0 1.2e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Dicty_REP PF05086.7 EMR65940.1 - 0.25 9.0 0.2 0.33 8.6 0.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein adh_short PF00106.20 EMR65941.1 - 5.3e-10 39.4 0.0 8.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR65941.1 - 2.7e-07 30.4 0.0 3.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR65941.1 - 0.00011 21.6 0.0 0.00017 21.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR65941.1 - 0.00015 20.7 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein MutS_V PF00488.16 EMR65943.1 - 2.3e-78 262.8 0.3 4.9e-78 261.7 0.0 1.6 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EMR65943.1 - 2.3e-53 180.9 0.1 4.3e-53 180.1 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EMR65943.1 - 4.3e-33 113.7 0.1 8.9e-33 112.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EMR65943.1 - 1.9e-13 50.6 0.6 8.2e-13 48.6 0.0 2.3 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EMR65943.1 - 2.3e-12 46.9 1.0 6e-12 45.5 0.7 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 EMR65943.1 - 0.00088 19.6 4.6 0.0022 18.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EMR65943.1 - 0.02 14.4 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EMR65943.1 - 0.042 13.8 3.0 0.072 13.0 0.2 2.6 2 0 0 2 2 2 0 AAA domain Ribonuc_red_2_N PF08471.5 EMR65943.1 - 0.08 13.0 1.6 0.13 12.3 0.3 2.0 2 0 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase Peptidase_C6 PF00851.13 EMR65943.1 - 0.17 10.5 0.2 0.29 9.6 0.2 1.3 1 0 0 1 1 1 0 Helper component proteinase PC_rep PF01851.17 EMR65944.1 - 2.7e-42 140.6 20.0 5.2e-08 32.6 0.0 10.0 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EMR65944.1 - 5.7e-17 61.7 0.0 2.7e-12 46.7 0.0 4.7 3 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EMR65944.1 - 7.4e-09 34.9 0.0 0.75 10.0 0.0 6.1 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EMR65944.1 - 3.5e-08 33.6 0.3 0.00016 22.0 0.0 4.9 4 1 0 4 4 4 1 HEAT-like repeat Codanin-1_C PF15296.1 EMR65944.1 - 0.093 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Codanin-1 C-terminus AP_endonuc_2 PF01261.19 EMR65945.1 - 4.2e-25 88.2 0.0 6.5e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AATase PF07247.7 EMR65946.1 - 1.5e-09 36.9 0.0 4.8e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 Alcohol acetyltransferase Condensation PF00668.15 EMR65946.1 - 1.7e-06 27.1 0.0 2.9e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.7 EMR65947.1 - 5e-30 104.2 0.0 3.4e-29 101.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EMR65947.1 - 1.4e-17 63.2 0.0 2.2e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EMR65947.1 - 1.2e-11 44.5 0.0 1.9e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMR65947.1 - 2.9e-09 37.0 0.0 5.5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EMR65947.1 - 2.8e-05 22.9 0.0 4.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMR65947.1 - 0.04 13.8 0.4 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Methyltransf_3 PF01596.12 EMR65948.1 - 1.2e-11 44.0 0.0 1.3e-11 43.9 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 EMR65948.1 - 0.00017 21.2 0.1 0.00019 21.0 0.1 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Crystall_2 PF09076.5 EMR65948.1 - 0.073 12.8 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin GCD14 PF08704.5 EMR65948.1 - 0.14 11.6 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit GDPD PF03009.12 EMR65949.1 - 1.1e-13 51.3 0.0 1.6e-13 50.8 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF3431 PF11913.3 EMR65950.1 - 6.4e-40 136.9 1.0 1.2e-29 103.3 0.0 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3431) Trypan_PARP PF05887.6 EMR65950.1 - 0.11 12.3 13.5 0.19 11.5 9.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AAA_22 PF13401.1 EMR65951.1 - 0.0017 18.4 0.0 0.0041 17.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EMR65951.1 - 0.0018 18.5 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 EMR65951.1 - 0.0018 17.7 0.2 0.0037 16.7 0.0 1.5 2 0 0 2 2 2 1 AAA-like domain NACHT PF05729.7 EMR65951.1 - 0.0045 16.6 0.9 0.016 14.8 0.6 2.0 1 1 0 1 1 1 1 NACHT domain DUF258 PF03193.11 EMR65951.1 - 0.0095 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EMR65951.1 - 0.01 15.7 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EMR65951.1 - 0.026 14.8 0.1 0.081 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMR65951.1 - 0.042 13.4 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMR65951.1 - 0.043 13.3 0.1 0.091 12.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EMR65951.1 - 0.044 13.7 0.0 0.14 12.0 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 EMR65951.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 EMR65951.1 - 0.13 13.0 0.0 0.77 10.5 0.0 2.3 3 1 0 3 3 3 0 AAA domain Peroxidase_2 PF01328.12 EMR65952.1 - 3.5e-12 45.6 1.8 7.7e-12 44.4 0.8 1.9 2 1 0 2 2 2 1 Peroxidase, family 2 Glyco_hydro_18 PF00704.23 EMR65953.1 - 1.4e-52 179.2 0.0 1.7e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 YadA_anchor PF03895.10 EMR65953.1 - 0.037 14.0 0.3 0.09 12.8 0.2 1.6 1 0 0 1 1 1 0 YadA-like C-terminal region Glyco_hydro_47 PF01532.15 EMR65954.1 - 2.9e-154 514.0 0.0 3.3e-154 513.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FAD_binding_4 PF01565.18 EMR65955.1 - 2.5e-23 82.0 0.2 5.7e-23 80.9 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR65955.1 - 0.00025 20.8 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like MARVEL PF01284.18 EMR65956.1 - 1.2e-10 41.3 26.9 2e-10 40.6 18.7 1.4 1 1 0 1 1 1 1 Membrane-associating domain Myb_DNA-bind_6 PF13921.1 EMR65957.1 - 1.6e-07 31.2 0.6 5.6e-07 29.5 0.4 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMR65957.1 - 0.0013 18.7 0.0 0.0029 17.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rap1_C PF11626.3 EMR65957.1 - 0.009 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain ADH_N PF08240.7 EMR65958.1 - 3.5e-18 65.3 0.6 1.1e-17 63.7 0.2 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR65958.1 - 4e-08 32.8 0.6 2.2e-06 27.2 0.4 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EMR65958.1 - 0.00028 20.4 0.5 0.00028 20.4 0.4 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 EMR65958.1 - 0.00052 18.5 0.6 0.00074 18.0 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EMR65958.1 - 0.016 14.1 0.7 0.022 13.6 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR65958.1 - 0.042 12.7 0.8 0.078 11.8 0.6 1.4 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EMR65958.1 - 0.075 12.4 0.2 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NACHT PF05729.7 EMR65959.1 - 2.4e-12 46.8 0.2 7e-12 45.3 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMR65959.1 - 7.7e-09 35.7 1.2 9.1e-08 32.2 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMR65959.1 - 4e-08 33.4 0.0 1.1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EMR65959.1 - 0.0015 18.8 0.0 0.0051 17.1 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 EMR65959.1 - 0.002 17.5 0.2 0.059 12.8 0.1 3.0 1 1 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 EMR65959.1 - 0.0021 18.8 0.4 0.018 15.8 0.0 2.7 3 1 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EMR65959.1 - 0.0043 17.3 0.0 0.013 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EMR65959.1 - 0.006 16.5 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 EMR65959.1 - 0.0062 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 EMR65959.1 - 0.025 13.5 0.2 1.3 7.9 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain AAA_29 PF13555.1 EMR65959.1 - 0.038 13.5 0.1 0.085 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 EMR65959.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EMR65959.1 - 0.057 13.1 0.1 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 EMR65959.1 - 0.075 12.8 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EMR65959.1 - 0.093 12.6 0.0 0.34 10.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMR65959.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Miro PF08477.8 EMR65959.1 - 0.17 12.4 0.1 0.53 10.8 0.0 1.9 2 0 0 2 2 1 0 Miro-like protein AAA_23 PF13476.1 EMR65959.1 - 0.39 11.0 5.0 9.8 6.4 0.9 2.5 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EMR65960.1 - 7.9e-17 61.5 0.0 7.9e-17 61.5 0.0 2.7 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EMR65960.1 - 2.2e-09 37.2 0.1 9.2e-09 35.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMR65960.1 - 3e-07 30.0 0.3 2.1e-06 27.2 0.2 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.8 EMR65960.1 - 0.0028 16.5 0.0 0.0074 15.1 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EMR65960.1 - 0.064 13.7 0.1 0.67 10.4 0.1 2.6 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EMR65960.1 - 0.074 12.6 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Peptidase_C78 PF07910.8 EMR65961.1 - 8.8e-49 165.5 0.0 6.1e-46 156.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase family C78 Hemerythrin PF01814.18 EMR65962.1 - 2.7e-15 56.6 4.2 3.7e-15 56.2 2.9 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PLU-1 PF08429.6 EMR65962.1 - 0.013 14.4 0.5 0.018 13.9 0.4 1.1 1 0 0 1 1 1 0 PLU-1-like protein DUF39 PF01837.11 EMR65962.1 - 0.16 10.5 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF39 FAD_binding_4 PF01565.18 EMR65963.1 - 6.8e-17 61.2 0.1 1.2e-14 53.9 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 EMR65964.1 - 9.1e-36 123.2 14.2 9.1e-36 123.2 9.8 2.5 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR65964.1 - 1.8e-11 43.3 9.6 1.8e-11 43.3 6.7 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EMR65964.1 - 2.5e-06 26.0 3.7 4.6e-06 25.1 2.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HMG_box PF00505.14 EMR65965.1 - 1.6e-21 76.3 0.4 3.6e-21 75.2 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMR65965.1 - 9.3e-06 25.9 0.1 9.3e-06 25.9 0.1 1.9 2 0 0 2 2 2 1 HMG-box domain KGG PF10685.4 EMR65966.1 - 9.6e-25 85.9 17.6 8.3e-11 41.5 0.4 3.6 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif SAP25 PF15476.1 EMR65966.1 - 2.7 7.4 5.7 8.4 5.8 0.5 2.0 1 1 1 2 2 2 0 Histone deacetylase complex subunit SAP25 GHL6 PF14871.1 EMR65968.1 - 4.3e-21 75.3 0.0 9.5e-21 74.2 0.0 1.6 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 Glyco_hydro_42M PF08532.5 EMR65968.1 - 2e-09 36.9 0.0 6.6e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase trimerisation domain Glyco_hydro_42 PF02449.10 EMR65968.1 - 1.8e-05 24.0 0.0 7.5e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase DUF187 PF02638.10 EMR65968.1 - 0.013 14.3 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 DUF4350 PF14258.1 EMR65968.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) LigB PF02900.13 EMR65970.1 - 9.2e-16 57.6 0.1 1.6e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Aldedh PF00171.17 EMR65970.1 - 2.8e-12 45.7 0.1 9.7e-09 34.0 0.0 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family adh_short_C2 PF13561.1 EMR65971.1 - 1.7e-25 90.2 0.0 2.1e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR65971.1 - 1.3e-23 83.7 0.0 1.7e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR65971.1 - 1e-07 31.7 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR65971.1 - 0.099 12.0 0.0 0.21 10.9 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Histidinol_dh PF00815.15 EMR65973.1 - 9.9e-117 390.0 0.1 1.2e-116 389.7 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase PepX_C PF08530.5 EMR65975.1 - 2.7e-33 115.7 0.2 4e-33 115.1 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 EMR65975.1 - 1.7e-21 76.8 0.0 2.6e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FAD_binding_3 PF01494.14 EMR65976.1 - 8.8e-23 80.9 0.0 1.3e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.6 EMR65976.1 - 1.6e-14 53.8 0.0 2.4e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.1 EMR65976.1 - 8.8e-08 32.0 0.5 2.6e-07 30.5 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR65976.1 - 9.6e-08 31.3 0.1 2.3e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Cupin_2 PF07883.6 EMR65976.1 - 2.1e-07 30.3 0.0 5.8e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Pyr_redox_2 PF07992.9 EMR65976.1 - 1.9e-05 24.6 0.1 5.4e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR65976.1 - 0.0002 20.3 0.4 0.00032 19.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMR65976.1 - 0.0003 21.1 0.2 0.0022 18.3 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR65976.1 - 0.0028 16.7 0.0 0.0067 15.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 EMR65976.1 - 0.0031 16.2 0.0 0.011 14.3 0.0 1.9 3 0 0 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EMR65976.1 - 0.0034 16.3 0.0 0.63 8.9 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMR65976.1 - 0.011 15.7 0.0 0.06 13.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EMR65976.1 - 0.018 14.6 0.1 0.047 13.2 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cupin_3 PF05899.7 EMR65976.1 - 0.097 12.0 0.0 0.28 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Haem_bd PF14376.1 EMR65976.1 - 0.13 11.9 0.1 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Haem-binding domain HI0933_like PF03486.9 EMR65976.1 - 0.15 10.5 0.3 0.22 9.9 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_10 PF13460.1 EMR65977.1 - 9e-07 29.0 0.0 1.8e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR65977.1 - 1.5e-05 24.4 0.0 3.2e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family SRP19 PF01922.12 EMR65978.1 - 1.1e-27 96.3 0.1 1.7e-27 95.8 0.1 1.3 1 0 0 1 1 1 1 SRP19 protein adh_short PF00106.20 EMR65979.1 - 2.4e-19 69.8 3.5 6.7e-19 68.4 2.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR65979.1 - 3.3e-14 53.2 0.2 4e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR65979.1 - 2.2e-08 33.9 0.8 3.5e-08 33.3 0.6 1.2 1 0 0 1 1 1 1 KR domain Metallophos PF00149.23 EMR65980.1 - 0.05 12.9 0.8 0.17 11.2 0.6 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Slp PF03843.8 EMR65980.1 - 0.058 12.3 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family F-box PF00646.28 EMR65982.1 - 0.093 12.4 0.4 0.093 12.4 0.3 1.7 2 0 0 2 2 2 0 F-box domain TIP49 PF06068.8 EMR65983.1 - 9e-185 614.0 0.1 1e-184 613.8 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EMR65983.1 - 3.3e-10 40.2 0.7 3.2e-06 27.3 0.1 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMR65983.1 - 3.9e-09 35.8 0.2 7.9e-06 25.0 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMR65983.1 - 1.7e-05 25.0 0.4 0.11 12.5 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 EMR65983.1 - 4.3e-05 23.1 0.1 0.00013 21.6 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EMR65983.1 - 9.7e-05 22.4 0.0 0.0084 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 EMR65983.1 - 0.0001 22.3 0.1 0.00025 21.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMR65983.1 - 0.0017 18.1 0.3 0.044 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EMR65983.1 - 0.0036 16.7 0.0 0.021 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EMR65983.1 - 0.0075 15.7 0.3 0.015 14.6 0.2 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2075 PF09848.4 EMR65983.1 - 0.011 14.7 0.1 0.027 13.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EMR65983.1 - 0.013 15.7 0.1 0.031 14.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EMR65983.1 - 0.019 14.4 0.1 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 EMR65983.1 - 0.02 14.0 0.1 0.56 9.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EMR65983.1 - 0.039 14.7 0.1 0.096 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EMR65983.1 - 0.1 11.7 0.2 0.24 10.4 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin Phytase-like PF13449.1 EMR65984.1 - 7.3e-27 94.4 0.0 1e-26 94.0 0.0 1.4 1 1 0 1 1 1 1 Esterase-like activity of phytase FAD_binding_3 PF01494.14 EMR65985.1 - 3.2e-14 52.7 0.0 3.7e-13 49.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR65985.1 - 6.2e-05 22.0 0.4 9e-05 21.5 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMR65985.1 - 0.0008 18.4 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EMR65985.1 - 0.01 14.4 0.0 1.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 120_Rick_ant PF12574.3 EMR65985.1 - 0.038 13.1 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen Med10 PF09748.4 EMR65986.1 - 4.9e-40 136.2 3.5 8.6e-40 135.5 2.4 1.4 1 1 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex NEMO PF11577.3 EMR65986.1 - 0.039 13.7 0.2 0.9 9.3 0.0 2.1 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO ETS_PEA3_N PF04621.8 EMR65986.1 - 0.061 12.5 0.5 0.071 12.3 0.4 1.1 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Sporozoite_P67 PF05642.6 EMR65986.1 - 0.15 9.8 6.0 0.23 9.2 3.3 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen SSP160 PF06933.6 EMR65986.1 - 0.74 7.7 8.5 0.97 7.3 5.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF515 PF04415.7 EMR65986.1 - 7.2 4.7 8.6 9.6 4.3 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Iso_dh PF00180.15 EMR65987.1 - 9.7e-126 419.3 0.0 1.1e-125 419.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase p450 PF00067.17 EMR65988.1 - 7.1e-17 61.0 0.1 8.2e-17 60.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 EMR65989.1 - 0.082 11.3 0.4 1.5 7.1 0.2 2.2 1 1 0 1 1 1 0 Transferase family RPA_C PF08784.6 EMR65990.1 - 3.8e-17 62.5 0.0 7.7e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EMR65990.1 - 9.3e-10 38.2 0.1 2e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain 2OG-FeII_Oxy PF03171.15 EMR65991.1 - 1.2e-19 70.4 0.0 1.9e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMR65991.1 - 8.3e-16 58.5 0.0 1.3e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal NUDIX PF00293.23 EMR65992.1 - 3.8e-29 101.0 0.0 5.8e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_7 PF13508.1 EMR65993.1 - 3.4e-07 30.3 0.1 6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR65993.1 - 1.5e-05 24.9 0.1 3.1e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EMR65993.1 - 0.0014 18.4 0.1 0.0031 17.3 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR65993.1 - 0.0016 18.5 0.1 0.0041 17.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR65993.1 - 0.012 15.3 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 EMR65993.1 - 0.032 14.1 0.0 0.082 12.8 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase bZIP_1 PF00170.16 EMR65994.1 - 2.5e-08 33.7 14.2 4.8e-08 32.8 9.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 EMR65994.1 - 0.00012 21.9 3.5 0.00086 19.0 2.5 2.1 1 1 0 1 1 1 1 Transcription factor PAP1 bZIP_Maf PF03131.12 EMR65994.1 - 0.00075 19.7 9.2 0.0013 19.0 6.3 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF972 PF06156.8 EMR65994.1 - 0.023 15.0 0.7 0.049 13.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ADIP PF11559.3 EMR65994.1 - 0.029 14.2 11.4 0.31 10.9 8.4 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CCDC155 PF14662.1 EMR65994.1 - 0.039 13.5 6.7 0.096 12.2 4.2 1.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 LMSTEN PF07988.7 EMR65994.1 - 0.058 12.6 0.4 6.5 6.1 0.0 2.5 2 0 0 2 2 2 0 LMSTEN motif BLOC1_2 PF10046.4 EMR65994.1 - 0.089 12.9 1.5 0.22 11.6 1.0 1.6 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 EMR65994.1 - 0.1 12.5 1.4 0.18 11.7 1.0 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.10 EMR65994.1 - 0.12 12.1 16.7 0.12 12.1 9.2 2.2 1 1 1 2 2 2 0 Basic region leucine zipper Adeno_PIX PF03955.9 EMR65994.1 - 0.13 12.8 1.8 0.26 11.8 1.3 1.5 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) PEP-utilisers_N PF05524.8 EMR65994.1 - 0.17 11.7 4.9 0.19 11.5 2.5 1.7 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal APG6 PF04111.7 EMR65994.1 - 0.3 10.1 3.4 0.63 9.0 2.3 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Glutaredoxin2_C PF04399.8 EMR65994.1 - 0.3 10.6 2.7 0.51 9.9 1.9 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain NAM-associated PF14303.1 EMR65994.1 - 0.34 11.2 7.0 0.51 10.6 4.9 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DivIC PF04977.10 EMR65994.1 - 0.72 9.3 4.5 1.6 8.2 3.1 1.6 1 0 0 1 1 1 0 Septum formation initiator M PF02370.11 EMR65994.1 - 5.2 7.7 7.9 4.7 7.9 0.8 2.8 1 1 0 2 2 2 0 M protein repeat UDPGT PF00201.13 EMR65995.1 - 1.4e-07 30.4 0.0 1.8e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EMR65995.1 - 0.00015 21.4 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.15 EMR65995.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_1_3 PF13528.1 EMR65995.1 - 0.18 10.9 0.0 0.53 9.4 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 1 TauD PF02668.11 EMR65996.1 - 4.6e-40 137.9 0.1 5.9e-40 137.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RIH_assoc PF08454.6 EMR65996.1 - 0.16 11.5 0.1 2 8.0 0.1 2.2 2 0 0 2 2 2 0 RyR and IP3R Homology associated DUF4238 PF14022.1 EMR65997.1 - 3.6e-35 121.5 1.1 5.4e-35 120.9 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Spore_YpjB PF09577.5 EMR65997.1 - 0.1 12.1 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) DUF1485 PF07364.7 EMR65998.1 - 1.8e-75 253.8 0.0 2.5e-75 253.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1485) MlrC_C PF07171.7 EMR65998.1 - 4.9e-39 133.6 0.0 9.2e-39 132.8 0.0 1.5 1 0 0 1 1 1 1 MlrC C-terminus Pox_F11 PF04943.7 EMR65999.1 - 0.0054 15.6 0.6 0.0054 15.6 0.4 1.5 2 0 0 2 2 2 1 Poxvirus F11 protein Laminin_II PF06009.7 EMR65999.1 - 0.06 13.1 3.2 0.5 10.1 1.3 2.7 2 1 0 2 2 2 0 Laminin Domain II Prominin PF05478.6 EMR65999.1 - 0.11 9.9 3.8 0.27 8.7 2.6 1.5 1 1 0 1 1 1 0 Prominin DUF1664 PF07889.7 EMR65999.1 - 0.32 10.8 5.2 0.22 11.3 0.8 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) HisKA_3 PF07730.8 EMR65999.1 - 1.3 9.3 5.0 42 4.5 0.2 4.0 2 1 3 5 5 5 0 Histidine kinase DUF791 PF05631.9 EMR66000.1 - 8.1e-31 106.9 1.5 5e-25 87.9 0.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF791) MFS_1 PF07690.11 EMR66000.1 - 1.5e-13 50.2 14.2 1e-12 47.4 4.1 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMR66000.1 - 5.5e-05 22.8 0.1 0.00024 20.8 0.0 2.2 2 0 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.19 EMR66000.1 - 0.00018 20.2 0.5 0.00018 20.2 0.3 2.7 4 1 1 5 5 5 1 Sugar (and other) transporter ATG22 PF11700.3 EMR66000.1 - 0.034 12.6 5.8 0.79 8.1 0.4 3.0 3 0 0 3 3 3 0 Vacuole effluxer Atg22 like adh_short PF00106.20 EMR66001.1 - 2.6e-20 73.0 0.0 3.9e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR66001.1 - 9.6e-07 28.6 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR66001.1 - 0.00032 20.5 0.0 0.0004 20.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EMR66001.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Clr5 PF14420.1 EMR66002.1 - 3.7e-20 71.5 3.0 8.8e-20 70.3 2.1 1.7 1 0 0 1 1 1 1 Clr5 domain RTA1 PF04479.8 EMR66003.1 - 2.3e-11 43.6 7.9 2.1e-10 40.5 5.5 2.0 1 1 0 1 1 1 1 RTA1 like protein NmrA PF05368.8 EMR66005.1 - 3.4e-16 59.2 0.0 4.3e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR66005.1 - 2e-12 47.4 0.2 2.9e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EMR66005.1 - 0.0042 17.3 0.3 0.01 16.1 0.2 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EMR66005.1 - 0.0097 15.3 0.1 0.034 13.5 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.11 EMR66005.1 - 0.01 16.3 0.2 0.03 14.8 0.1 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_4 PF07993.7 EMR66005.1 - 0.02 13.8 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Transferase PF02458.10 EMR66007.1 - 4.3e-18 64.9 0.0 7.5e-17 60.8 0.0 2.0 1 1 0 1 1 1 1 Transferase family Peptidase_M24 PF00557.19 EMR66008.1 - 2.8e-38 131.5 0.1 4.1e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EMR66008.1 - 1.1e-10 42.1 0.0 1.6e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Pectate_lyase PF03211.8 EMR66009.1 - 1.6e-78 263.0 1.9 2.1e-78 262.6 1.3 1.1 1 0 0 1 1 1 1 Pectate lyase AAA PF00004.24 EMR66010.1 - 7.1e-40 136.2 0.0 1.3e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMR66010.1 - 0.00012 21.7 0.1 0.00056 19.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMR66010.1 - 0.00014 21.9 0.1 0.0099 15.8 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EMR66010.1 - 0.00022 20.3 0.0 0.00047 19.2 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EMR66010.1 - 0.00052 20.1 0.9 0.015 15.4 0.0 2.7 2 1 0 3 3 2 1 AAA domain AAA_2 PF07724.9 EMR66010.1 - 0.0011 18.8 0.0 0.0066 16.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EMR66010.1 - 0.0032 16.7 0.2 0.035 13.3 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EMR66010.1 - 0.0049 16.0 0.1 0.013 14.6 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EMR66010.1 - 0.006 15.5 0.0 0.012 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EMR66010.1 - 0.0092 15.8 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMR66010.1 - 0.014 15.1 0.4 0.035 13.8 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EMR66010.1 - 0.018 15.8 0.1 0.062 14.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMR66010.1 - 0.019 14.3 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EMR66010.1 - 0.027 13.8 1.5 0.3 10.4 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EMR66010.1 - 0.044 13.3 0.1 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EMR66010.1 - 0.08 12.8 0.0 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EMR66010.1 - 0.095 11.7 0.1 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Acyl_transf_1 PF00698.16 EMR66012.1 - 5.9e-12 45.5 0.9 9.3e-07 28.4 0.8 2.1 1 1 1 2 2 2 2 Acyl transferase domain RRM_1 PF00076.17 EMR66014.1 - 5.4e-38 128.4 2.0 1.7e-18 65.9 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR66014.1 - 1.1e-29 102.1 0.2 8.5e-15 54.5 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR66014.1 - 1.8e-13 50.0 0.2 5e-05 23.0 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMR66014.1 - 0.0045 16.7 0.1 1.4 8.7 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Mgr1 PF08602.5 EMR66014.1 - 0.094 11.7 1.3 0.14 11.1 0.9 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit MAS20 PF02064.10 EMR66014.1 - 9.2 6.2 9.5 21 5.0 6.6 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor Cons_hypoth698 PF03601.9 EMR66015.1 - 0.099 11.2 0.5 0.12 11.0 0.4 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 698 MENTAL PF10457.4 EMR66015.1 - 0.11 12.1 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Cholesterol-capturing domain DUF3154 PF11351.3 EMR66015.1 - 0.18 11.5 2.5 0.22 11.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) MFS_1 PF07690.11 EMR66015.1 - 0.56 8.8 8.8 0.3 9.7 3.6 1.9 2 0 0 2 2 2 0 Major Facilitator Superfamily ADH_zinc_N PF00107.21 EMR66016.1 - 3.1e-11 42.9 0.5 2.1e-10 40.2 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EMR66016.1 - 1.3e-06 28.5 0.1 2.3e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding ADH_N PF08240.7 EMR66016.1 - 1.7e-06 27.7 0.1 8e-06 25.5 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EMR66016.1 - 0.00029 20.4 0.2 0.0005 19.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.8 EMR66016.1 - 0.00048 19.4 0.3 0.00077 18.7 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family FAD_binding_2 PF00890.19 EMR66018.1 - 8.4e-95 318.0 0.5 9.7e-95 317.8 0.3 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR66018.1 - 7.4e-09 34.9 2.1 5.6e-07 28.7 0.1 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR66018.1 - 3.2e-08 33.4 0.8 1.3e-07 31.5 0.6 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMR66018.1 - 2.6e-07 30.0 0.2 5.5e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMR66018.1 - 3.2e-07 29.7 0.5 3.2e-07 29.7 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EMR66018.1 - 2e-06 27.8 0.0 6.5e-05 22.8 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR66018.1 - 7.5e-06 25.0 0.6 1.5e-05 24.0 0.4 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EMR66018.1 - 3.2e-05 23.1 0.3 8.1e-05 21.8 0.2 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EMR66018.1 - 0.00011 22.5 1.0 0.042 14.2 0.3 3.7 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR66018.1 - 0.00013 22.1 0.3 0.00028 21.0 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR66018.1 - 0.00082 17.9 0.2 0.00082 17.9 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 EMR66018.1 - 0.0031 16.5 0.0 0.0052 15.7 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein GMC_oxred_N PF00732.14 EMR66018.1 - 0.061 12.4 0.3 6 5.9 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase Amino_oxidase PF01593.19 EMR66018.1 - 0.13 11.2 0.1 0.13 11.2 0.1 2.5 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.9 EMR66018.1 - 0.27 10.5 0.8 1.1 8.6 0.2 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aminotran_4 PF01063.14 EMR66019.1 - 1.6e-22 80.1 0.0 2.2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Glyco_hydro_18 PF00704.23 EMR66020.1 - 0.056 12.8 1.5 0.069 12.5 1.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 Nsp1_C PF05064.8 EMR66020.1 - 0.23 11.1 3.4 0.65 9.6 0.1 2.4 2 1 0 2 2 2 0 Nsp1-like C-terminal region Cwf_Cwc_15 PF04889.7 EMR66020.1 - 0.33 10.6 11.9 0.4 10.3 8.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2524 PF10732.4 EMR66020.1 - 0.45 10.6 4.5 2 8.5 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) Prominin PF05478.6 EMR66020.1 - 0.54 7.7 3.1 0.66 7.4 2.1 1.2 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.10 EMR66020.1 - 1.8 7.6 7.2 5.6 6.0 5.0 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit ATP-synt_B PF00430.13 EMR66020.1 - 2.1 8.1 6.6 1.3 8.7 0.1 2.6 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) INO80_Ies4 PF08193.6 EMR66021.1 - 3.4e-70 236.4 23.3 4.2e-70 236.1 16.1 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 DUF1793 PF08760.6 EMR66022.1 - 2.5e-63 212.9 0.6 4.2e-63 212.2 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Mpp10 PF04006.7 EMR66023.1 - 4e-88 296.2 82.8 1.4e-85 287.9 57.4 3.0 1 1 0 1 1 1 1 Mpp10 protein Bac_luciferase PF00296.15 EMR66024.1 - 3.8e-57 193.7 1.3 6.6e-57 192.9 0.9 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase CTP_transf_2 PF01467.21 EMR66025.1 - 2.6e-18 66.5 0.0 2.9e-14 53.3 0.0 3.2 2 1 0 2 2 2 2 Cytidylyltransferase ERG4_ERG24 PF01222.12 EMR66027.1 - 4.1e-143 477.0 21.8 4.9e-143 476.7 15.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DAO PF01266.19 EMR66028.1 - 2.8e-55 187.6 0.7 4.2e-54 183.8 0.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR66028.1 - 2.6e-05 24.1 0.4 0.00017 21.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR66028.1 - 0.00047 20.0 0.0 0.00082 19.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR66028.1 - 0.0015 17.6 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EMR66028.1 - 0.0017 17.2 6.6 0.0026 16.6 0.8 2.3 2 1 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EMR66028.1 - 0.0019 17.1 0.0 0.0019 17.1 0.0 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein Mqo PF06039.10 EMR66028.1 - 0.0075 14.4 0.0 0.01 14.0 0.0 1.1 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.14 EMR66028.1 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain RabGAP-TBC PF00566.13 EMR66029.1 - 7.6e-44 149.7 0.1 1.1e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SSF PF00474.12 EMR66030.1 - 2e-21 76.1 28.6 3.3e-21 75.3 19.8 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family PhyH PF05721.8 EMR66031.1 - 3.9e-57 193.6 0.0 5.8e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EMR66031.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase MFS_1 PF07690.11 EMR66032.1 - 4.6e-41 140.7 19.4 5.7e-40 137.1 13.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2776 PF10951.3 EMR66032.1 - 0.011 14.8 5.3 0.095 11.7 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2776) DUF3169 PF11368.3 EMR66032.1 - 0.017 14.3 0.3 2.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) ESSS PF10183.4 EMR66032.1 - 0.027 14.8 0.0 0.082 13.3 0.0 1.9 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pox_A14 PF05767.7 EMR66032.1 - 0.23 11.4 2.1 2.2 8.2 0.0 3.0 3 1 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF4231 PF14015.1 EMR66032.1 - 0.32 10.9 2.5 4.8 7.1 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) NfeD PF01957.13 EMR66032.1 - 0.48 10.5 6.6 24 5.0 1.4 3.3 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding Ank PF00023.25 EMR66033.1 - 1.4e-14 53.0 2.1 1.4e-05 24.6 0.6 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EMR66033.1 - 9.7e-14 51.4 0.4 5.4e-07 29.8 0.4 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMR66033.1 - 7.6e-12 45.0 3.7 0.00011 22.3 0.0 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR66033.1 - 4.8e-11 41.7 1.3 0.0063 16.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EMR66033.1 - 9.9e-10 38.6 1.9 0.01 16.3 0.0 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) DUF1888 PF08985.6 EMR66033.1 - 0.061 12.9 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1888) PPR_2 PF13041.1 EMR66034.1 - 3.4e-12 46.1 0.1 1.1e-05 25.3 0.0 3.8 4 1 1 5 5 5 2 PPR repeat family PPR_1 PF12854.2 EMR66034.1 - 1.1e-10 40.7 0.0 8.3e-06 25.1 0.0 3.4 3 0 0 3 3 3 2 PPR repeat PPR PF01535.15 EMR66034.1 - 1.5e-10 40.3 0.2 0.00097 18.9 0.0 4.0 3 1 0 4 4 4 2 PPR repeat PPR_3 PF13812.1 EMR66034.1 - 1e-08 34.7 0.2 0.0029 17.7 0.0 4.2 4 0 0 4 4 4 2 Pentatricopeptide repeat domain CorA PF01544.13 EMR66035.1 - 2e-10 40.1 0.3 2.8e-10 39.7 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GPDPase_memb PF10110.4 EMR66035.1 - 0.054 12.9 0.5 0.11 11.9 0.4 1.4 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF1539 PF07560.6 EMR66035.1 - 0.16 11.8 0.0 0.52 10.1 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Ceramidase_alk PF04734.8 EMR66036.1 - 4.5e-271 900.5 0.0 1.3e-270 899.0 0.0 1.6 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Pkinase PF00069.20 EMR66038.1 - 2.3e-76 256.3 0.0 3.2e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR66038.1 - 6.9e-39 133.4 0.0 9.8e-39 132.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EMR66038.1 - 1.5e-17 63.5 0.2 4.6e-17 61.9 0.2 1.9 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EMR66038.1 - 7.5e-08 31.6 0.0 4.2e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EMR66038.1 - 0.00045 19.6 0.4 0.00088 18.6 0.3 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EMR66038.1 - 0.0028 16.2 0.1 0.0045 15.6 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EMR66038.1 - 0.037 13.7 1.1 0.48 10.1 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EMR66038.1 - 0.072 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adap_comp_sub PF00928.16 EMR66039.1 - 4e-60 203.1 0.0 1.5e-59 201.2 0.0 1.7 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMR66039.1 - 0.00043 20.0 0.0 0.00063 19.4 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain cNMP_binding PF00027.24 EMR66040.1 - 1.9e-39 133.3 0.0 2.7e-19 68.7 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain BNR_2 PF13088.1 EMR66041.1 - 9.3e-09 34.9 0.2 0.00026 20.3 0.0 2.3 2 0 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EMR66041.1 - 0.096 12.5 2.6 0.38 10.7 1.8 2.1 1 0 0 1 1 1 0 BNR/Asp-box repeat CLTH PF10607.4 EMR66042.1 - 9.9e-36 122.5 0.1 1.6e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EMR66042.1 - 5.1e-20 71.8 0.1 9e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EMR66042.1 - 4.3e-06 26.3 0.4 2.2e-05 24.0 0.1 2.4 2 0 0 2 2 2 1 LisH DUF387 PF04079.11 EMR66042.1 - 0.037 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) BCAS2 PF05700.6 EMR66043.1 - 5.3e-40 137.2 0.3 6.3e-40 136.9 0.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) tRNA_U5-meth_tr PF05958.6 EMR66045.1 - 2e-11 43.1 0.0 1.1e-09 37.4 0.0 2.9 3 1 0 3 3 3 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EMR66045.1 - 2.4e-06 27.1 0.0 4.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR66045.1 - 2.2e-05 24.9 0.0 6.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EMR66045.1 - 0.00024 20.6 0.0 0.00041 19.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRAM PF01938.15 EMR66045.1 - 0.00026 20.7 0.2 0.00076 19.2 0.1 1.8 1 0 0 1 1 1 1 TRAM domain Methyltransf_26 PF13659.1 EMR66045.1 - 0.0017 18.3 0.1 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR66045.1 - 0.011 16.1 0.1 0.058 13.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMR66045.1 - 0.072 13.4 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EMR66045.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UNC45-central PF11701.3 EMR66046.1 - 3.3e-42 143.8 0.1 4.5e-41 140.1 0.0 3.0 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 EMR66046.1 - 0.0019 18.4 18.1 0.027 14.7 0.3 5.1 4 2 1 5 5 5 2 HEAT repeats Arm PF00514.18 EMR66046.1 - 0.011 15.5 15.1 6.1 6.8 0.0 8.1 9 1 0 9 9 9 0 Armadillo/beta-catenin-like repeat G_glu_transpept PF01019.16 EMR66047.1 - 6.8e-155 516.4 1.4 9.8e-155 515.8 1.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1479 PF07350.7 EMR66048.1 - 2e-122 408.6 0.0 2.3e-122 408.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) DUF4279 PF14106.1 EMR66049.1 - 0.094 12.5 1.7 0.23 11.3 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) BLOC1_2 PF10046.4 EMR66049.1 - 2.6 8.2 10.5 0.17 12.0 0.2 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin PF02996.12 EMR66049.1 - 3.4 7.3 7.0 4.2 7.0 0.6 3.0 2 1 0 2 2 2 0 Prefoldin subunit Spc7 PF08317.6 EMR66049.1 - 3.6 6.1 15.2 0.22 10.1 6.2 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein ATP_transf PF09830.4 EMR66050.1 - 1.4e-16 60.0 0.1 2.7e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase EamA PF00892.15 EMR66051.1 - 6.6 6.7 22.0 0.31 11.0 2.2 2.9 3 0 0 3 3 3 0 EamA-like transporter family HET PF06985.6 EMR66053.1 - 3.4e-18 66.1 4.8 1.7e-14 54.1 3.3 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HTH_IclR PF09339.5 EMR66054.1 - 0.014 15.0 0.0 2.8 7.5 0.0 3.3 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_24 PF13412.1 EMR66054.1 - 0.11 11.9 0.0 0.51 9.7 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HET PF06985.6 EMR66056.1 - 3.1e-25 88.9 0.0 5.2e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribonuc_L-PSP PF01042.16 EMR66058.1 - 1.1e-23 83.3 0.0 1.4e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Utp12 PF04003.7 EMR66058.1 - 0.1 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Dip2/Utp12 Family FMO-like PF00743.14 EMR66059.1 - 1.2e-14 53.4 0.0 1.1e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMR66059.1 - 3e-14 53.5 0.0 1.7e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR66059.1 - 6e-10 38.9 0.0 1.2e-08 34.8 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR66059.1 - 2e-08 34.3 0.0 2.3e-07 30.8 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR66059.1 - 1e-07 31.1 0.0 9.4e-06 24.7 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMR66059.1 - 1.7e-07 31.1 0.2 1.1e-06 28.5 0.0 2.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EMR66059.1 - 0.00054 19.1 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EMR66059.1 - 0.0019 17.1 0.0 0.021 13.7 0.0 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR66059.1 - 0.0039 17.5 0.1 7.3 7.0 0.1 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMR66059.1 - 0.0098 15.0 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EMR66059.1 - 0.041 12.9 0.0 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EMR66059.1 - 0.15 10.5 0.0 0.23 9.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein SR-25 PF10500.4 EMR66059.1 - 9.9 5.5 7.5 16 4.8 5.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF334 PF03904.8 EMR66060.1 - 0.064 12.5 5.3 0.11 11.7 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) RHSP PF07999.6 EMR66060.1 - 0.22 10.0 2.7 0.41 9.1 0.3 2.0 2 0 0 2 2 2 0 Retrotransposon hot spot protein Med11 PF10280.4 EMR66060.1 - 0.55 10.2 10.6 8.1 6.5 7.4 3.0 1 1 0 1 1 1 0 Mediator complex protein AAA_13 PF13166.1 EMR66060.1 - 0.79 8.1 14.4 2.2 6.6 0.2 2.2 1 1 0 2 2 2 0 AAA domain HisKA PF00512.20 EMR66060.1 - 0.94 9.5 15.2 8 6.5 0.2 4.8 4 0 0 4 4 4 0 His Kinase A (phospho-acceptor) domain DUF4618 PF15397.1 EMR66060.1 - 3.3 6.9 18.8 0.055 12.8 5.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) RRF PF01765.14 EMR66060.1 - 9.8 5.6 11.9 1.5 8.3 3.1 2.8 2 2 1 3 3 3 0 Ribosome recycling factor Glyco_transf_90 PF05686.7 EMR66061.1 - 2.4e-25 89.0 1.8 3.2e-25 88.6 1.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EMR66061.1 - 0.0051 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 2-Hacid_dh_C PF02826.14 EMR66062.1 - 1.9e-53 180.2 0.0 2.9e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMR66062.1 - 2.1e-32 111.3 0.0 2.5e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMR66062.1 - 0.00051 19.9 0.0 0.002 18.0 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sulfatase PF00884.18 EMR66063.1 - 4.3e-60 203.5 0.7 5.8e-60 203.0 0.5 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EMR66063.1 - 0.047 12.1 0.0 0.073 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) TFR_dimer PF04253.10 EMR66064.1 - 1.5e-16 60.1 0.0 2.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EMR66064.1 - 1.8e-16 60.4 0.0 3e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EMR66064.1 - 0.0012 18.4 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 adh_short PF00106.20 EMR66065.1 - 1.3e-24 86.9 0.1 2.5e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR66065.1 - 5.4e-22 78.7 0.0 7.8e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAD_binding_3 PF01494.14 EMR66065.1 - 2e-19 69.9 3.4 3.4e-10 39.5 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain KR PF08659.5 EMR66065.1 - 1.2e-05 25.0 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMR66065.1 - 0.00014 21.0 0.0 0.0003 20.0 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_8 PF13450.1 EMR66065.1 - 0.0002 21.2 0.3 0.002 18.1 0.0 2.9 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EMR66065.1 - 0.00034 20.3 0.0 0.088 12.4 0.0 2.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EMR66065.1 - 0.0036 17.2 0.0 0.43 10.5 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.11 EMR66065.1 - 0.0051 16.2 0.0 3.4 7.1 0.0 2.5 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Epimerase PF01370.16 EMR66065.1 - 0.007 15.8 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR66065.1 - 0.017 15.1 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 0 NADH(P)-binding Sox_N PF12444.3 EMR66065.1 - 0.021 15.9 0.0 0.062 14.4 0.0 1.8 1 0 0 1 1 1 0 Sox developmental protein N terminal Pyr_redox PF00070.22 EMR66065.1 - 0.037 14.4 0.0 0.2 12.0 0.0 2.3 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EMR66065.1 - 0.04 13.3 0.0 2.6 7.3 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RmlD_sub_bind PF04321.12 EMR66065.1 - 0.067 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Pyr_redox_2 PF07992.9 EMR66065.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EMR66065.1 - 0.17 10.7 0.0 5 5.8 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase Methyltransf_16 PF10294.4 EMR66067.1 - 9.6e-26 90.2 0.1 1.4e-25 89.7 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EMR66067.1 - 4.4e-08 32.6 0.0 6.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EMR66067.1 - 4.6e-08 32.6 0.1 7.1e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EMR66067.1 - 3.7e-07 30.7 0.1 6.3e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR66067.1 - 7.5e-06 26.3 0.1 1.3e-05 25.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR66067.1 - 9.3e-06 25.2 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR66067.1 - 1.6e-05 24.9 0.1 2.5e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR66067.1 - 0.00026 20.7 0.0 0.00037 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EMR66067.1 - 0.00035 20.2 0.1 0.00093 18.8 0.1 1.7 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.7 EMR66067.1 - 0.0015 19.0 0.1 0.0032 17.9 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EMR66067.1 - 0.0025 16.9 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.10 EMR66067.1 - 0.0074 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 EMR66067.1 - 0.016 15.5 0.1 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EMR66067.1 - 0.084 12.3 0.1 0.25 10.8 0.1 1.8 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Esterase_phd PF10503.4 EMR66069.1 - 2.1e-07 30.3 3.3 3.9e-07 29.5 2.3 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EMR66069.1 - 2.1e-05 24.2 1.7 4.5e-05 23.2 0.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR66069.1 - 0.00056 19.1 0.3 0.0022 17.2 0.2 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 EMR66069.1 - 0.0014 17.2 0.3 0.0034 15.9 0.2 1.6 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 EMR66069.1 - 0.0035 17.2 0.6 0.023 14.5 0.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMR66069.1 - 0.051 12.9 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.8 EMR66069.1 - 0.057 12.8 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EMR66069.1 - 0.15 11.4 1.1 4.6 6.6 0.0 2.9 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase SSP160 PF06933.6 EMR66070.1 - 0.0085 14.1 12.9 0.011 13.7 9.0 1.0 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 EMR66070.1 - 0.055 13.2 6.8 0.079 12.7 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 EMR66070.1 - 0.46 8.1 1.5 0.54 7.9 1.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Asp PF00026.18 EMR66071.1 - 3.9e-46 157.7 6.6 3.3e-36 125.1 2.2 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMR66071.1 - 5.1e-09 36.2 0.1 2e-08 34.3 0.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EMR66071.1 - 0.00049 19.6 0.2 0.045 13.3 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Kelch_4 PF13418.1 EMR66071.1 - 0.0074 16.0 0.4 0.026 14.2 0.1 2.0 2 0 0 2 2 2 1 Galactose oxidase, central domain Glyco_hydro_61 PF03443.9 EMR66073.1 - 3e-46 157.9 0.2 3.5e-46 157.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 tRNA-synt_1c PF00749.16 EMR66074.1 - 1e-94 316.7 0.0 1.3e-94 316.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EMR66074.1 - 4.7e-29 101.2 0.0 1.4e-28 99.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Sugar_tr PF00083.19 EMR66075.1 - 1.1e-73 248.3 19.9 1.4e-73 247.9 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR66075.1 - 2.6e-18 65.8 41.7 8.2e-17 60.9 15.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NPP1 PF05630.6 EMR66076.1 - 5.9e-70 235.2 0.0 7e-70 234.9 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) CN_hydrolase PF00795.17 EMR66078.1 - 4.1e-20 71.9 0.0 6e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FAD_binding_3 PF01494.14 EMR66079.1 - 6e-26 91.3 0.0 1.2e-25 90.3 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR66079.1 - 0.025 13.4 1.7 0.25 10.1 0.9 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR66079.1 - 0.041 13.8 0.3 0.1 12.6 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 EMR66079.1 - 0.12 11.2 0.0 0.29 9.9 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Glyco_hydro_61 PF03443.9 EMR66080.1 - 2.1e-46 158.4 0.6 2.6e-46 158.1 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cgr1 PF03879.9 EMR66083.1 - 5e-25 87.7 31.1 5.3e-25 87.7 21.6 1.0 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.7 EMR66083.1 - 2.3 8.5 14.1 2.8 8.2 9.7 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal CAF-1_p150 PF11600.3 EMR66083.1 - 2.8 7.2 27.6 3.3 7.0 19.1 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ndufs5 PF10200.4 EMR66083.1 - 4.6 7.2 9.7 9.1 6.3 6.7 1.6 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Birna_RdRp PF04197.7 EMR66083.1 - 6.1 4.7 9.9 6 4.7 6.9 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Spc7 PF08317.6 EMR66084.1 - 0.0083 14.8 0.4 0.011 14.4 0.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Fib_alpha PF08702.5 EMR66084.1 - 0.034 14.2 0.7 0.17 12.0 0.5 1.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 EMR66084.1 - 0.045 14.0 0.9 0.1 12.9 0.6 1.7 1 1 0 1 1 1 0 Snapin/Pallidin AAA_13 PF13166.1 EMR66084.1 - 0.058 11.8 0.3 0.08 11.3 0.2 1.1 1 0 0 1 1 1 0 AAA domain DHC_N1 PF08385.7 EMR66084.1 - 0.063 11.6 0.2 0.086 11.2 0.2 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Ax_dynein_light PF10211.4 EMR66084.1 - 0.066 13.0 2.1 0.093 12.5 0.5 1.8 1 1 1 2 2 2 0 Axonemal dynein light chain DUF3357 PF11837.3 EMR66084.1 - 0.071 12.9 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) ABC2_membrane_2 PF12679.2 EMR66084.1 - 0.078 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein EMP24_GP25L PF01105.19 EMR66084.1 - 0.11 12.2 0.5 0.16 11.6 0.3 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Nup54 PF13874.1 EMR66084.1 - 0.12 12.0 2.1 0.45 10.1 0.3 2.4 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Syntaxin-6_N PF09177.6 EMR66084.1 - 0.22 11.9 5.5 1.4 9.3 1.9 2.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Syntaxin PF00804.20 EMR66084.1 - 0.29 11.3 4.6 0.97 9.6 1.8 2.4 2 1 0 2 2 1 0 Syntaxin IncA PF04156.9 EMR66084.1 - 0.58 9.7 9.7 0.51 9.8 3.5 2.5 1 1 1 2 2 2 0 IncA protein COG2 PF06148.6 EMR66084.1 - 0.62 9.9 3.7 0.69 9.7 1.0 2.1 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Med9 PF07544.8 EMR66084.1 - 0.84 9.4 5.8 1.5 8.6 2.4 2.5 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Seryl_tRNA_N PF02403.17 EMR66084.1 - 1.3 9.0 6.0 4.2 7.4 1.3 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 EMR66084.1 - 1.6 8.2 4.5 1.2 8.6 0.9 2.3 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.7 EMR66084.1 - 2.3 8.6 6.0 0.82 10.0 0.8 2.5 3 0 0 3 3 2 0 SlyX DUF904 PF06005.7 EMR66084.1 - 3.4 8.0 6.3 6.3 7.1 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF904) FAD_binding_2 PF00890.19 EMR66085.1 - 6.6e-125 417.2 2.3 8e-125 416.9 1.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EMR66085.1 - 4e-46 156.0 0.2 5.9e-46 155.5 0.2 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 EMR66085.1 - 2.9e-06 26.5 0.2 0.0017 17.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.9 EMR66085.1 - 5.7e-05 23.0 0.1 0.036 13.9 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR66085.1 - 0.00023 20.1 0.7 0.038 12.8 0.9 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EMR66085.1 - 0.0015 17.5 0.1 0.0054 15.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMR66085.1 - 0.013 14.6 0.1 0.021 13.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EMR66085.1 - 0.15 10.4 0.8 0.47 8.8 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein DUF3818 PF12825.2 EMR66086.1 - 1.3e-134 448.1 3.8 1.9e-134 447.6 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EMR66086.1 - 9.1e-43 145.1 0.3 2.2e-42 143.9 0.2 1.6 1 0 0 1 1 1 1 PX-associated Myc_N PF01056.13 EMR66086.1 - 0.0035 16.5 1.3 0.0058 15.8 0.9 1.2 1 0 0 1 1 1 1 Myc amino-terminal region PX PF00787.19 EMR66086.1 - 0.0036 17.0 3.3 0.13 12.0 0.9 3.1 2 1 0 2 2 2 1 PX domain UQ_con PF00179.21 EMR66087.1 - 1.2e-28 99.2 0.0 1.5e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMR66087.1 - 0.06 13.1 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 EMR66087.1 - 0.13 12.1 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain DUF3433 PF11915.3 EMR66088.1 - 3.7e-08 33.3 0.2 8.7e-08 32.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) MFS_1 PF07690.11 EMR66089.1 - 5.3e-30 104.3 23.7 5.6e-30 104.2 15.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 EMR66091.1 - 5.1e-26 91.5 0.4 1.6e-24 86.7 0.1 2.0 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR66091.1 - 7.9e-25 88.0 0.0 9.4e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR66091.1 - 6.6e-06 25.9 0.1 8.3e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 EMR66091.1 - 0.003 17.3 0.1 0.0071 16.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EMR66091.1 - 0.056 12.8 0.0 0.098 12.0 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family BTV_NS2 PF04514.7 EMR66092.1 - 0.05 12.4 21.3 0.17 10.7 10.5 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 DUF4551 PF15087.1 EMR66092.1 - 5.2 5.3 8.2 6.9 4.8 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-CCHC PF00098.18 EMR66093.1 - 2.3e-45 150.4 57.2 4.1e-08 32.7 2.0 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EMR66093.1 - 2e-10 40.1 40.9 0.075 12.7 0.7 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EMR66093.1 - 6e-07 29.0 42.3 0.013 15.2 0.0 6.9 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.1 EMR66093.1 - 0.022 14.4 47.5 0.065 12.9 0.1 6.8 6 1 1 7 7 7 0 Zinc knuckle zf-CCHC_2 PF13696.1 EMR66093.1 - 0.078 12.4 0.3 0.078 12.4 0.2 7.1 4 2 3 7 7 7 0 Zinc knuckle Sporozoite_P67 PF05642.6 EMR66093.1 - 0.94 7.2 4.7 0.92 7.2 3.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_16 PF00722.16 EMR66094.1 - 2.7e-16 59.4 0.0 4.7e-16 58.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EMR66094.1 - 7.5e-08 30.9 0.2 0.0039 15.4 0.1 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Lipocalin_4 PF13648.1 EMR66094.1 - 0.046 14.3 1.5 2.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Lipocalin-like domain Abhydrolase_6 PF12697.2 EMR66097.1 - 1.6e-18 67.4 0.0 1.5e-17 64.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR66097.1 - 0.0017 18.1 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR66097.1 - 0.0054 16.3 0.0 0.021 14.3 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMR66097.1 - 0.024 14.4 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Ndr PF03096.9 EMR66097.1 - 0.037 12.5 0.0 0.066 11.6 0.0 1.3 1 0 0 1 1 1 0 Ndr family Sulfatase PF00884.18 EMR66098.1 - 3e-75 253.2 0.0 3.5e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 EMR66098.1 - 2.2e-05 24.7 1.3 0.00057 20.1 0.1 2.5 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 EMR66098.1 - 0.0015 17.9 0.0 0.068 12.4 0.0 2.3 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EMR66098.1 - 0.032 12.6 0.0 0.048 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) adh_short PF00106.20 EMR66099.1 - 6.5e-16 58.6 0.0 8.6e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR66099.1 - 4.2e-06 26.5 0.0 6.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR66099.1 - 0.00028 20.9 0.0 0.00049 20.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EMR66099.1 - 0.002 17.9 0.0 0.0027 17.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR66099.1 - 0.022 14.1 0.0 0.056 12.8 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EMR66099.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1751 PF08551.5 EMR66100.1 - 6.7e-05 23.1 0.6 0.00013 22.1 0.4 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EMR66100.1 - 0.034 14.1 4.1 0.098 12.6 2.8 1.7 1 1 0 1 1 1 0 Rhomboid family Sugar_tr PF00083.19 EMR66102.1 - 0.0026 16.4 7.0 0.0026 16.4 4.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 EMR66102.1 - 0.031 12.4 0.8 0.049 11.7 0.5 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector FlhC PF05280.6 EMR66102.1 - 0.066 12.6 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) MFS_1 PF07690.11 EMR66102.1 - 0.15 10.7 13.8 0.074 11.7 7.1 1.9 2 0 0 2 2 2 0 Major Facilitator Superfamily DUF983 PF06170.7 EMR66102.1 - 0.25 11.4 1.6 0.63 10.1 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Myco_19_kDa PF05481.7 EMR66102.1 - 0.85 9.4 4.2 1.3 8.8 2.6 1.6 1 1 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen HET PF06985.6 EMR66103.1 - 6.4e-24 84.7 0.5 6.4e-24 84.7 0.4 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AAA PF00004.24 EMR66103.1 - 1.3e-15 57.7 0.0 4.9e-15 55.9 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR66103.1 - 0.0013 18.8 0.0 0.0062 16.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR66103.1 - 0.0088 16.0 0.0 0.035 14.0 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EMR66103.1 - 0.016 14.9 0.1 0.13 11.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EMR66103.1 - 0.049 13.9 0.2 0.36 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EMR66103.1 - 0.051 14.4 4.3 0.058 14.2 0.0 3.2 3 1 1 4 4 4 0 AAA domain Zeta_toxin PF06414.7 EMR66103.1 - 0.067 12.2 0.1 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Vps36_ESCRT-II PF11605.3 EMR66103.1 - 0.078 12.7 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 AAA_19 PF13245.1 EMR66103.1 - 0.089 12.5 0.4 0.23 11.2 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EMR66103.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 EMR66104.1 - 1.5e-34 118.1 0.0 7.2e-14 51.9 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMR66104.1 - 3.9e-22 77.7 1.9 2.9e-05 24.1 0.1 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EMR66104.1 - 8.4e-22 75.8 6.5 2.4e-05 23.9 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EMR66104.1 - 1.2e-19 70.2 1.5 0.00014 22.2 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR66104.1 - 1.6e-17 61.8 2.3 0.0035 17.4 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat GST_C_3 PF14497.1 EMR66105.1 - 5.1e-08 33.3 0.0 9.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMR66105.1 - 2.5e-06 27.5 0.1 9.1e-05 22.5 0.0 2.8 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR66105.1 - 7.2e-06 25.9 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMR66105.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMR66105.1 - 0.023 14.9 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glyco_hydro_76 PF03663.9 EMR66106.1 - 0.00046 19.6 0.0 0.00057 19.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 adh_short PF00106.20 EMR66107.1 - 1.5e-06 28.2 0.4 2.5e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase Uds1 PF15456.1 EMR66108.1 - 9.1e-31 106.4 2.4 9.1e-31 106.4 1.7 5.9 3 1 3 6 6 6 2 Up-regulated During Septation Myosin_tail_1 PF01576.14 EMR66108.1 - 0.00017 19.4 55.7 0.00017 19.4 38.6 3.1 3 1 0 3 3 3 1 Myosin tail HR1 PF02185.11 EMR66108.1 - 0.0034 17.1 0.4 0.0034 17.1 0.3 5.9 4 2 1 5 5 5 2 Hr1 repeat DUF4164 PF13747.1 EMR66108.1 - 0.0045 17.0 10.2 0.0045 17.0 7.1 6.5 6 2 2 8 8 8 2 Domain of unknown function (DUF4164) DUF4140 PF13600.1 EMR66108.1 - 0.16 12.4 0.2 0.16 12.4 0.2 9.2 4 1 3 7 7 7 0 N-terminal domain of unknown function (DUF4140) AAA_13 PF13166.1 EMR66108.1 - 0.19 10.1 42.0 0.036 12.5 17.0 3.3 2 1 1 3 3 3 0 AAA domain Reo_sigmaC PF04582.7 EMR66108.1 - 0.35 10.0 12.5 0.62 9.1 0.7 3.2 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Cast PF10174.4 EMR66108.1 - 1.9 6.4 65.8 0.13 10.3 11.6 4.4 1 1 2 3 3 3 0 RIM-binding protein of the cytomatrix active zone MtrG PF04210.8 EMR66108.1 - 2.8 7.6 6.0 28 4.4 0.0 4.1 4 1 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G PHD PF00628.24 EMR66109.1 - 4.7e-10 39.0 7.8 8.1e-10 38.2 5.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EMR66109.1 - 0.0057 15.9 2.0 0.01 15.1 1.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EMR66109.1 - 0.063 13.4 3.1 0.22 11.7 2.1 1.9 1 1 1 2 2 2 0 PHD-like zinc-binding domain Epimerase PF01370.16 EMR66110.1 - 5.7e-05 22.6 0.0 7.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR66110.1 - 0.033 14.1 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_4 PF07993.7 EMR66110.1 - 0.033 13.0 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Pyr_redox_2 PF07992.9 EMR66111.1 - 5.4e-06 26.4 0.0 1.3e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMR66111.1 - 0.0017 17.5 0.1 0.0034 16.5 0.1 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase His_Phos_2 PF00328.17 EMR66112.1 - 1.2e-34 120.2 0.0 5e-20 72.1 0.0 2.1 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) V_ATPase_I PF01496.14 EMR66113.1 - 9.4e-298 989.3 0.0 1.1e-297 989.1 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ERM PF00769.14 EMR66113.1 - 0.098 12.1 3.4 0.16 11.5 0.1 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Filament PF00038.16 EMR66113.1 - 0.11 11.9 12.5 0.059 12.8 0.6 2.4 2 1 0 2 2 2 0 Intermediate filament protein Laminin_II PF06009.7 EMR66113.1 - 0.39 10.4 5.5 5.2 6.8 0.2 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF4140 PF13600.1 EMR66113.1 - 0.6 10.5 4.2 6.8 7.1 0.2 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CCDC-167 PF15188.1 EMR66113.1 - 0.65 9.9 6.8 3.1 7.7 0.2 2.8 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 IncA PF04156.9 EMR66113.1 - 1.2 8.7 12.6 0.12 11.9 1.5 3.1 3 0 0 3 3 3 0 IncA protein GAS PF13851.1 EMR66113.1 - 1.9 7.6 10.9 1.3 8.2 3.1 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 EMR66113.1 - 3.2 6.0 4.9 1.8 6.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Nup54 PF13874.1 EMR66113.1 - 3.9 7.1 7.9 0.7 9.5 1.1 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Rootletin PF15035.1 EMR66113.1 - 4.1 7.3 11.7 8.8 6.2 1.5 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.10 EMR66113.1 - 5.9 6.4 11.2 0.23 10.9 0.8 3.1 2 1 0 2 2 2 0 Septum formation initiator CENP-F_leu_zip PF10473.4 EMR66113.1 - 6.6 6.5 9.1 6.1 6.7 2.5 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Peptidase_S9 PF00326.16 EMR66114.1 - 7.2e-12 44.9 0.0 1.1e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMR66114.1 - 5.3e-07 29.7 1.7 9.1e-07 28.9 1.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR66114.1 - 6.7e-07 29.1 2.2 2.3e-06 27.4 1.6 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMR66114.1 - 5.9e-05 22.7 0.1 0.00051 19.6 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EMR66114.1 - 0.0025 17.6 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein K_channel_TID PF07941.6 EMR66114.1 - 0.01 16.0 2.3 0.01 16.0 1.6 3.1 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain DLH PF01738.13 EMR66114.1 - 0.057 12.6 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family RIP PF00161.14 EMR66115.1 - 2.4e-28 98.7 0.0 5e-28 97.6 0.0 1.5 2 0 0 2 2 2 1 Ribosome inactivating protein FAD_binding_4 PF01565.18 EMR66117.1 - 1.1e-24 86.5 0.8 1.7e-24 85.8 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR66117.1 - 9.2e-08 31.8 0.0 1.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Acetyltransf_1 PF00583.19 EMR66118.1 - 7.7e-06 25.8 0.0 2.1e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR66118.1 - 0.0018 18.4 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR66118.1 - 0.0018 18.3 0.0 0.0054 16.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR66118.1 - 0.018 14.9 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Prenyltransf PF01255.14 EMR66119.1 - 1.7e-85 285.6 0.0 2.9e-85 284.9 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase NBP1 PF08537.5 EMR66120.1 - 0.052 12.7 0.5 0.068 12.3 0.3 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 zf-C2H2 PF00096.21 EMR66120.1 - 0.13 12.6 0.2 0.24 11.8 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type APC_CDC26 PF10471.4 EMR66120.1 - 0.19 12.5 6.2 0.41 11.4 4.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Med3 PF11593.3 EMR66120.1 - 0.41 9.8 6.2 0.45 9.7 4.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal APG6 PF04111.7 EMR66120.1 - 0.46 9.4 3.0 0.58 9.1 2.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TP53IP5 PF15331.1 EMR66120.1 - 0.56 10.0 3.9 0.68 9.8 2.7 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 MSA_2 PF00985.12 EMR66120.1 - 1.7 8.7 5.8 2.7 8.0 4.0 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family DUF3987 PF13148.1 EMR66120.1 - 2.5 6.6 8.4 3.1 6.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) NARP1 PF12569.3 EMR66120.1 - 2.5 6.7 8.9 3.1 6.4 6.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 5-FTHF_cyc-lig PF01812.15 EMR66121.1 - 3e-13 49.9 0.0 3.8e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family GTP_EFTU PF00009.22 EMR66122.1 - 5.7e-64 215.0 0.2 8.3e-64 214.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EMR66122.1 - 1e-36 125.1 0.0 2.8e-36 123.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EMR66122.1 - 4.4e-21 74.5 0.0 2.9e-20 71.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMR66122.1 - 2.4e-13 49.9 1.6 8e-13 48.3 0.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EMR66122.1 - 3.1e-12 46.1 0.0 9.7e-12 44.5 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EMR66122.1 - 1.1e-05 25.3 0.2 2.5e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DAGK_cat PF00781.19 EMR66123.1 - 8.5e-07 28.4 0.1 2.8e-06 26.7 0.1 2.0 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain TRM PF02005.11 EMR66124.1 - 1.4e-100 336.8 0.0 2.6e-98 329.4 0.0 2.4 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 EMR66124.1 - 6e-05 23.0 0.1 0.00018 21.5 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EMR66124.1 - 0.0047 15.9 0.0 0.0094 15.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 EMR66124.1 - 0.013 14.9 0.0 0.079 12.3 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase small domain Met_10 PF02475.11 EMR66124.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.1 EMR66124.1 - 0.027 14.0 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EMR66124.1 - 0.033 14.7 0.0 0.071 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.17 EMR66125.1 - 1.6e-15 56.4 0.2 1.9e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain Img2 PF05046.9 EMR66125.1 - 0.14 12.3 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) DUF4231 PF14015.1 EMR66126.1 - 0.18 11.8 2.1 0.21 11.5 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) ABC_tran PF00005.22 EMR66127.1 - 3e-37 127.9 10.2 1.2e-22 80.6 0.0 3.6 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EMR66127.1 - 7.7e-13 49.0 0.2 0.0016 18.4 0.0 3.5 3 0 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EMR66127.1 - 4.7e-10 38.8 0.8 0.00033 20.1 0.0 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EMR66127.1 - 4.7e-08 32.9 0.1 0.0043 16.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EMR66127.1 - 9.2e-08 32.3 0.2 0.004 17.3 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EMR66127.1 - 1.9e-07 31.8 0.9 0.033 14.9 0.1 3.1 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 EMR66127.1 - 1.5e-06 28.7 0.1 0.055 13.9 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_28 PF13521.1 EMR66127.1 - 3.3e-06 27.1 0.4 0.0018 18.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMR66127.1 - 4.1e-06 27.1 3.8 0.081 13.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EMR66127.1 - 1.1e-05 24.6 0.9 0.018 14.2 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMR66127.1 - 1.2e-05 25.3 9.5 0.00064 19.7 0.7 3.0 2 1 0 2 2 2 2 AAA ATPase domain ABC_tran_2 PF12848.2 EMR66127.1 - 1.6e-05 24.6 5.0 1.6e-05 24.6 3.4 2.5 2 1 1 3 3 2 1 ABC transporter MobB PF03205.9 EMR66127.1 - 6.9e-05 22.5 0.4 0.54 9.9 0.0 2.9 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EMR66127.1 - 7.2e-05 22.5 0.0 0.052 13.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain ArgK PF03308.11 EMR66127.1 - 8.7e-05 21.4 1.4 0.044 12.5 0.1 2.5 2 0 0 2 2 2 2 ArgK protein AAA PF00004.24 EMR66127.1 - 0.00011 22.4 0.2 0.023 14.8 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EMR66127.1 - 0.00013 21.8 3.7 0.036 13.7 0.0 3.0 3 0 0 3 3 3 2 Archaeal ATPase AAA_30 PF13604.1 EMR66127.1 - 0.00016 21.3 2.4 0.15 11.6 0.0 3.2 3 1 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.13 EMR66127.1 - 0.00032 20.2 0.1 0.041 13.3 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_14 PF13173.1 EMR66127.1 - 0.00033 20.5 1.0 0.13 12.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 EMR66127.1 - 0.0004 20.2 12.7 0.058 13.2 0.1 3.6 3 1 0 3 3 3 2 Domain of unknown function DUF87 SMC_N PF02463.14 EMR66127.1 - 0.00054 19.2 8.7 0.73 9.0 0.0 4.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EMR66127.1 - 0.00057 19.7 3.7 0.21 11.4 0.0 3.1 3 1 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 EMR66127.1 - 0.0014 18.8 0.1 0.32 11.1 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_10 PF12846.2 EMR66127.1 - 0.0014 18.1 5.1 0.25 10.7 0.1 3.3 3 1 1 4 4 4 2 AAA-like domain AAA_19 PF13245.1 EMR66127.1 - 0.0016 18.1 1.2 0.11 12.2 0.0 3.4 4 0 0 4 4 3 1 Part of AAA domain DUF815 PF05673.8 EMR66127.1 - 0.0018 17.2 2.0 0.26 10.2 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 EMR66127.1 - 0.0021 17.4 0.0 0.14 11.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMR66127.1 - 0.0023 17.6 1.1 0.072 12.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 EMR66127.1 - 0.0031 17.0 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.4 EMR66127.1 - 0.0053 15.4 0.0 0.1 11.1 0.0 2.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class NTPase_1 PF03266.10 EMR66127.1 - 0.0067 16.1 0.2 2.7 7.7 0.0 2.6 2 0 0 2 2 2 1 NTPase Arf PF00025.16 EMR66127.1 - 0.0096 15.1 0.7 0.44 9.7 0.1 2.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Thymidylate_kin PF02223.12 EMR66127.1 - 0.011 15.0 4.6 1.3 8.3 0.0 3.4 3 0 0 3 3 3 0 Thymidylate kinase Dynamin_N PF00350.18 EMR66127.1 - 0.011 15.5 8.4 1.1 9.0 1.7 3.4 3 1 0 3 3 3 0 Dynamin family Viral_helicase1 PF01443.13 EMR66127.1 - 0.013 14.9 0.1 2 7.9 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_15 PF13175.1 EMR66127.1 - 0.036 13.1 10.2 0.36 9.8 0.2 3.9 3 1 0 4 4 3 0 AAA ATPase domain SbcCD_C PF13558.1 EMR66127.1 - 0.074 12.9 0.0 0.46 10.4 0.0 2.5 3 0 0 3 3 1 0 Putative exonuclease SbcCD, C subunit cobW PF02492.14 EMR66127.1 - 0.47 9.8 5.6 4.1 6.8 0.2 2.9 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EMR66127.1 - 8.7 6.6 36.4 0.6 10.3 0.2 4.0 2 1 0 2 2 1 0 AAA domain Xpo1 PF08389.7 EMR66128.1 - 1.9e-30 105.7 5.2 8.1e-30 103.6 0.4 3.7 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 EMR66128.1 - 0.00096 19.0 0.1 0.0033 17.3 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Ribosomal_S5_C PF03719.10 EMR66128.1 - 0.14 11.4 0.0 0.36 10.1 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain Adaptin_N PF01602.15 EMR66128.1 - 0.36 9.0 5.6 0.43 8.8 0.3 3.2 4 1 0 4 4 4 0 Adaptin N terminal region AMP-binding PF00501.23 EMR66129.1 - 2.1e-58 197.7 1.2 2.8e-22 78.7 0.0 4.8 4 2 1 5 5 5 4 AMP-binding enzyme DMAP_binding PF06464.6 EMR66129.1 - 2.3e-10 41.0 0.0 1.1e-09 38.8 0.0 2.0 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.7 EMR66129.1 - 0.039 13.7 0.4 0.11 12.3 0.3 1.7 1 0 0 1 1 1 0 Gas vesicle protein G PDEase_II PF02112.10 EMR66130.1 - 1.6e-25 89.7 0.0 3.3e-18 65.7 0.0 2.0 2 0 0 2 2 2 2 cAMP phosphodiesterases class-II CN_hydrolase PF00795.17 EMR66131.1 - 1.5e-17 63.5 0.1 6.2e-17 61.5 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.11 EMR66132.1 - 5.2e-13 48.4 31.1 5.2e-13 48.4 21.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMR66132.1 - 1.6e-09 37.4 4.2 4.9e-09 35.8 2.9 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EMR66132.1 - 0.2 10.2 20.3 1.9 6.9 13.5 2.3 1 1 0 1 1 1 0 Sugar (and other) transporter Glyco_hydro_3 PF00933.16 EMR66133.1 - 7.8e-91 304.1 0.0 1.1e-90 303.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR66133.1 - 5.2e-52 176.6 0.0 2.4e-51 174.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Peptidase_C48 PF02902.14 EMR66134.1 - 1.6e-07 31.1 0.0 1.8e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Flavin_Reduct PF01613.13 EMR66135.1 - 4.1e-19 68.9 0.1 5.9e-19 68.4 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Pkinase PF00069.20 EMR66136.1 - 0.0018 17.4 0.0 0.034 13.3 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR66136.1 - 0.0024 16.9 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_61 PF03443.9 EMR66139.1 - 1.6e-53 181.7 0.0 1.8e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TauD PF02668.11 EMR66141.1 - 7.4e-35 120.8 0.0 9.5e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EMR66142.1 - 1.2e-07 30.8 33.7 1.2e-07 30.8 23.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMR66142.1 - 2.7e-06 26.9 5.0 2.7e-06 26.9 3.4 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 FtsX PF02687.16 EMR66142.1 - 0.013 15.2 1.5 0.013 15.2 1.0 3.7 2 2 1 3 3 3 0 FtsX-like permease family UPF0154 PF03672.8 EMR66142.1 - 1.6 8.4 3.6 1.7 8.3 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) ATPase_gene1 PF09527.5 EMR66142.1 - 3.2 7.6 18.0 0.18 11.6 0.2 3.7 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit (ATPase_gene1) Lactamase_B_2 PF12706.2 EMR66143.1 - 2.6e-32 111.9 0.2 4.6e-32 111.1 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EMR66143.1 - 4.1e-25 87.0 0.1 1.4e-24 85.3 0.0 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 EMR66143.1 - 1.7e-15 57.2 0.4 5.2e-15 55.6 0.3 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_hydro_16 PF00722.16 EMR66144.1 - 4.2e-10 39.2 0.9 7.3e-10 38.4 0.6 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 C1-set PF07654.10 EMR66144.1 - 0.13 12.3 0.3 0.47 10.4 0.0 2.0 2 1 1 3 3 3 0 Immunoglobulin C1-set domain Epimerase PF01370.16 EMR66145.1 - 6.3e-12 45.4 0.0 1.2e-11 44.4 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR66145.1 - 6.9e-11 41.3 0.0 9.1e-11 40.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMR66145.1 - 1.3e-06 27.5 0.0 4.3e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EMR66145.1 - 2e-06 26.8 0.0 9.9e-06 24.6 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMR66145.1 - 1.4e-05 25.2 0.1 7.7e-05 22.7 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMR66145.1 - 0.00016 21.6 0.1 0.00038 20.3 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EMR66145.1 - 0.035 13.3 0.3 0.064 12.5 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family 2-Hacid_dh_C PF02826.14 EMR66145.1 - 0.078 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lyase_aromatic PF00221.14 EMR66146.1 - 2.9e-159 530.5 2.2 3.5e-159 530.2 1.6 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase CO_deh_flav_C PF03450.12 EMR66146.1 - 0.13 12.1 0.5 18 5.2 0.0 2.7 2 0 0 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain UbiA PF01040.13 EMR66147.1 - 3.6e-28 98.4 16.2 4.6e-28 98.1 11.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family FAD_binding_3 PF01494.14 EMR66148.1 - 5.3e-23 81.6 0.0 2.5e-22 79.4 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR66148.1 - 8.3e-11 41.3 0.1 5.4e-07 28.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR66148.1 - 5.1e-07 29.6 1.9 7.5e-07 29.0 0.4 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMR66148.1 - 1e-06 29.0 0.1 6e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR66148.1 - 2e-06 26.5 0.2 0.0011 17.4 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.19 EMR66148.1 - 2.1e-06 27.1 0.3 0.0034 16.5 0.3 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EMR66148.1 - 1.1e-05 24.4 0.1 1.4e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMR66148.1 - 0.00017 21.5 0.1 0.00078 19.3 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR66148.1 - 0.00093 19.3 0.0 0.0016 18.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMR66148.1 - 0.00098 17.8 0.2 0.022 13.4 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 EMR66148.1 - 0.0016 17.5 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EMR66148.1 - 0.0032 16.4 0.0 0.13 11.1 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 EMR66148.1 - 0.0038 16.1 0.4 0.0054 15.6 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.11 EMR66148.1 - 0.0039 16.6 0.5 0.0094 15.3 0.2 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EMR66148.1 - 0.0085 15.7 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EMR66148.1 - 0.0088 15.1 0.2 0.031 13.3 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMR66148.1 - 0.053 13.2 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_10 PF13460.1 EMR66148.1 - 0.085 12.8 0.3 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 EMR66148.1 - 0.14 11.5 0.1 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMR66148.1 - 0.14 11.9 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ADH_N PF08240.7 EMR66149.1 - 3.2e-08 33.2 0.0 8.5e-08 31.9 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR66149.1 - 6.4e-06 25.7 1.6 0.00013 21.4 0.3 2.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EMR66149.1 - 0.031 13.8 0.1 0.061 12.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.20 EMR66150.1 - 7.6e-12 45.4 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EMR66150.1 - 0.00042 19.8 0.0 0.015 14.7 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EMR66150.1 - 0.0069 16.0 0.0 0.016 14.8 0.0 1.6 2 0 0 2 2 2 1 KR domain NmrA PF05368.8 EMR66150.1 - 0.025 13.8 0.1 0.04 13.1 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family DUF3533 PF12051.3 EMR66151.1 - 0.048 12.4 1.4 0.082 11.6 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) p450 PF00067.17 EMR66152.1 - 1e-64 218.8 0.0 1.3e-64 218.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S7 PF00177.16 EMR66153.1 - 2.3e-13 50.0 0.1 1.1e-12 47.7 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S7p/S5e HET PF06985.6 EMR66154.1 - 1.5e-07 31.6 0.0 2.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mito_fiss_reg PF05308.6 EMR66154.1 - 0.11 11.8 6.9 0.23 10.8 4.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Pex14_N PF04695.8 EMR66154.1 - 0.9 9.5 3.3 1.7 8.7 1.6 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MFS_1 PF07690.11 EMR66155.1 - 5.2e-17 61.5 30.4 7e-17 61.1 21.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 EMR66156.1 - 9e-22 78.1 0.0 1.7e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR66156.1 - 3.8e-15 55.0 0.0 1.7e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMR66156.1 - 2.3e-09 36.6 0.6 6.4e-08 31.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMR66156.1 - 7e-09 35.5 0.0 2e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMR66156.1 - 1.9e-05 24.5 0.0 0.0034 17.1 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMR66156.1 - 0.00015 21.6 0.0 0.013 15.3 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EMR66156.1 - 0.0032 17.5 0.1 1.9 8.6 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EMR66156.1 - 0.012 14.4 0.0 0.29 9.9 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF4147 PF13660.1 EMR66156.1 - 0.02 14.0 0.0 0.11 11.5 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4147) Mqo PF06039.10 EMR66156.1 - 0.1 10.7 0.0 0.59 8.2 0.0 1.9 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) DUF1996 PF09362.5 EMR66158.1 - 1.1e-63 215.1 0.8 1.5e-63 214.6 0.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Nol1_Nop2_Fmu PF01189.12 EMR66159.1 - 3.2e-16 59.5 0.0 2.3e-10 40.3 0.0 2.9 2 1 0 2 2 2 2 NOL1/NOP2/sun family MFS_1 PF07690.11 EMR66160.1 - 4e-38 131.0 42.5 4e-38 131.0 29.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Whi5 PF08528.6 EMR66162.1 - 7e-09 35.0 0.0 1.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Whi5 like IR1-M PF12185.3 EMR66162.1 - 0.1 12.2 1.5 1.2 8.9 1.8 2.0 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain CDC45 PF02724.9 EMR66162.1 - 1 7.3 3.8 1.2 7.0 2.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Gtr1_RagA PF04670.7 EMR66163.1 - 2.3e-68 229.8 0.1 2.8e-68 229.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EMR66163.1 - 0.00064 19.0 0.0 0.0016 17.6 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 EMR66163.1 - 0.005 17.3 0.0 0.023 15.2 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Neurexophilin PF06312.7 EMR66164.1 - 0.032 13.4 0.6 0.033 13.4 0.4 1.1 1 0 0 1 1 1 0 Neurexophilin Ank_2 PF12796.2 EMR66165.1 - 6.7e-14 51.9 0.3 2e-05 24.8 0.0 4.2 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMR66165.1 - 2.2e-10 40.7 1.3 7.3e-06 26.3 0.0 4.7 3 2 1 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.25 EMR66165.1 - 1.8e-08 33.7 2.2 0.058 13.2 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EMR66165.1 - 2.6e-08 33.3 0.1 0.0038 17.3 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EMR66165.1 - 3.6e-08 33.4 1.3 0.0073 16.5 0.0 5.4 4 2 1 5 5 5 1 Ankyrin repeats (many copies) FAD_binding_4 PF01565.18 EMR66166.1 - 6.7e-10 38.5 2.1 0.00026 20.4 0.5 2.9 1 1 1 2 2 2 2 FAD binding domain BBE PF08031.7 EMR66166.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like SET PF00856.23 EMR66168.1 - 1e-08 35.6 0.4 2.2e-08 34.5 0.1 1.7 2 0 0 2 2 2 1 SET domain TPR_12 PF13424.1 EMR66168.1 - 1.1e-05 25.2 1.9 2.6e-05 24.0 1.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMR66168.1 - 1.8 9.4 5.5 4.5 8.1 2.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat peroxidase PF00141.18 EMR66169.1 - 2.9e-22 79.3 0.1 4.8e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 Peroxidase Hydantoinase_B PF02538.9 EMR66171.1 - 5.9e-148 493.3 0.0 4.9e-147 490.3 0.0 2.1 2 1 0 2 2 2 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EMR66171.1 - 4.1e-84 282.1 0.6 6.4e-84 281.4 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EMR66171.1 - 2.1e-54 183.6 0.0 7.3e-53 178.6 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.11 EMR66172.1 - 8.3e-28 97.1 35.1 5.1e-21 74.7 12.9 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily zf-RING_2 PF13639.1 EMR66173.1 - 2.4e-09 36.8 8.2 5.2e-09 35.7 5.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMR66173.1 - 7.9e-08 32.3 2.5 2.3e-07 30.8 1.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EMR66173.1 - 3e-06 27.0 9.3 1.3e-05 25.0 6.5 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EMR66173.1 - 0.00011 21.9 2.4 0.00032 20.4 1.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 EMR66173.1 - 0.00042 19.9 3.5 0.00042 19.9 2.4 2.0 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 EMR66173.1 - 0.00057 19.4 10.1 0.0012 18.4 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EMR66173.1 - 0.00065 19.6 8.5 0.0017 18.3 5.9 1.8 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_3 PF13920.1 EMR66173.1 - 0.0012 18.5 5.6 0.0022 17.5 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMR66173.1 - 0.0043 17.0 9.1 0.01 15.8 6.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EMR66173.1 - 0.076 13.0 8.2 0.16 12.0 5.7 1.6 1 0 0 1 1 1 0 RING-like domain Baculo_RING PF05883.6 EMR66173.1 - 0.13 12.1 2.3 0.26 11.1 1.6 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain PHD PF00628.24 EMR66173.1 - 1.2 8.9 7.4 2.4 7.8 5.1 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 EMR66173.1 - 1.6 8.3 8.1 32 4.2 5.6 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 EMR66173.1 - 4.4 7.1 6.8 22 4.8 4.9 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 RhoGAP PF00620.22 EMR66174.1 - 1.2e-18 67.1 0.0 3.3e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain SBF PF01758.11 EMR66175.1 - 5.1e-49 166.2 11.8 5.1e-49 166.2 8.2 2.7 4 0 0 4 4 4 1 Sodium Bile acid symporter family Glyco_hydro_30 PF02055.11 EMR66176.1 - 8.1e-17 60.5 0.7 1.6e-09 36.5 0.1 2.1 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EMR66176.1 - 2.4e-11 43.1 3.0 7e-10 38.3 0.0 2.5 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 PI-PLC-X PF00388.14 EMR66177.1 - 1.2e-45 154.4 0.0 2e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EMR66177.1 - 2.8e-32 111.1 0.0 4.7e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain YL1 PF05764.8 EMR66177.1 - 0.02 14.4 0.7 0.042 13.4 0.5 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Fungal_trans PF04082.13 EMR66178.1 - 7.2e-28 97.1 0.0 3e-27 95.1 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1707 PF08044.6 EMR66178.1 - 0.0019 17.9 1.6 0.0046 16.6 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) DUF3067 PF11267.3 EMR66178.1 - 0.22 11.6 0.4 0.76 9.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3067) Hist_deacetyl PF00850.14 EMR66179.1 - 3.4e-29 102.1 0.0 5.8e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.6 EMR66179.1 - 0.048 13.3 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 RTP801 C-terminal region PAT1 PF09770.4 EMR66179.1 - 9.7 4.2 22.6 6 4.9 14.7 1.3 1 1 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GCD14_N PF14801.1 EMR66180.1 - 0.13 11.8 0.7 0.2 11.2 0.4 1.4 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Palm_thioest PF02089.10 EMR66181.1 - 1.1e-57 195.1 0.0 1.3e-57 194.8 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 EMR66181.1 - 0.017 14.2 0.0 0.052 12.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.13 EMR66181.1 - 0.033 13.4 0.0 0.19 10.9 0.0 1.9 1 1 0 1 1 1 0 Lipase (class 2) DUF3425 PF11905.3 EMR66182.1 - 4.6e-24 84.8 0.0 1.3e-23 83.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EMR66182.1 - 0.047 13.6 2.6 0.078 12.9 1.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor Plasmodium_Vir PF05795.6 EMR66182.1 - 0.1 11.7 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein bZIP_2 PF07716.10 EMR66182.1 - 0.14 12.0 3.4 0.25 11.2 2.4 1.3 1 0 0 1 1 1 0 Basic region leucine zipper ParA PF10609.4 EMR66183.1 - 8.7e-34 115.2 0.0 1.8e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EMR66183.1 - 1.8e-15 56.9 0.0 2.5e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EMR66183.1 - 1.1e-05 25.3 0.0 3.5e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EMR66183.1 - 0.00028 20.0 0.0 0.00062 18.9 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EMR66183.1 - 0.00049 19.2 0.2 0.0018 17.3 0.1 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EMR66183.1 - 0.0037 16.6 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMR66183.1 - 0.0098 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_26 PF13500.1 EMR66183.1 - 0.023 14.2 0.1 5.1 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EMR66183.1 - 0.027 15.2 0.1 0.047 14.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 EMR66183.1 - 0.051 12.7 0.0 0.27 10.3 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.1 EMR66183.1 - 0.056 13.5 0.0 0.14 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EMR66183.1 - 0.056 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 EMR66183.1 - 0.07 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EMR66183.1 - 0.079 12.5 0.2 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain Zn_Tnp_IS1595 PF12760.2 EMR66183.1 - 0.093 12.5 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NTPase_1 PF03266.10 EMR66183.1 - 0.1 12.3 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 NTPase T2SE PF00437.15 EMR66183.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein SNF2_N PF00176.18 EMR66184.1 - 6e-46 156.5 0.0 4.6e-35 120.8 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EMR66184.1 - 5.6e-11 42.1 0.1 1.3e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LEP503 PF15221.1 EMR66184.1 - 0.12 12.0 0.0 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 BCS1_N PF08740.6 EMR66185.1 - 9.1e-41 139.5 0.1 1.2e-40 139.0 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EMR66185.1 - 1e-17 64.5 0.0 1.8e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMR66185.1 - 1.4e-05 25.9 0.0 4.8e-05 24.1 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EMR66185.1 - 6.6e-05 22.3 0.0 0.0002 20.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EMR66185.1 - 0.00022 20.3 0.1 0.0058 15.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EMR66185.1 - 0.0008 19.3 0.0 0.0024 17.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMR66185.1 - 0.0028 17.3 0.0 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EMR66185.1 - 0.0031 16.9 0.0 0.0079 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.8 EMR66185.1 - 0.0035 16.2 0.0 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_21 PF13304.1 EMR66185.1 - 0.0064 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EMR66185.1 - 0.0065 16.7 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EMR66185.1 - 0.0088 16.1 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR66185.1 - 0.012 15.5 0.0 0.038 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EMR66185.1 - 0.019 14.0 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EMR66185.1 - 0.024 14.9 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EMR66185.1 - 0.042 14.3 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 1 0 Miro-like protein MMR_HSR1 PF01926.18 EMR66185.1 - 0.047 13.6 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase Herpes_Helicase PF02689.9 EMR66185.1 - 0.061 11.0 0.0 1.1 6.9 0.0 2.0 2 0 0 2 2 2 0 Helicase DUF258 PF03193.11 EMR66185.1 - 0.063 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EMR66185.1 - 0.068 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 EMR66185.1 - 0.083 13.0 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PPV_E1_C PF00519.12 EMR66185.1 - 0.13 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase DUF2464 PF10240.4 EMR66186.1 - 0.23 10.7 2.4 0.24 10.7 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) DUF3632 PF12311.3 EMR66187.1 - 6e-12 45.7 0.0 2.2e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) Glyco_hydro_3 PF00933.16 EMR66188.1 - 3.7e-82 275.6 0.0 5.3e-82 275.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR66188.1 - 2.1e-41 141.9 0.1 3.1e-40 138.0 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR66188.1 - 6.1e-22 77.3 0.0 1.1e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Cofilin_ADF PF00241.15 EMR66190.1 - 3.4e-12 46.3 0.0 3.9e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ank PF00023.25 EMR66191.1 - 6.5e-17 60.4 3.3 0.048 13.4 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.2 EMR66191.1 - 6.8e-16 58.3 0.0 6.6e-08 32.7 0.0 4.2 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMR66191.1 - 8.4e-14 50.3 0.5 0.47 10.8 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EMR66191.1 - 6.8e-08 32.8 0.4 5.1 7.7 0.0 6.1 6 1 0 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR66191.1 - 7.5e-06 26.0 5.2 5.5 7.3 0.0 6.2 6 1 0 6 6 6 2 Ankyrin repeats (many copies) Nod_GRP PF07806.6 EMR66191.1 - 0.12 12.0 3.2 0.19 11.3 2.2 1.3 1 0 0 1 1 1 0 Nodule-specific GRP repeat SicP-binding PF09119.5 EMR66191.1 - 0.15 11.7 0.2 8.7 6.1 0.1 2.6 2 0 0 2 2 2 0 SicP binding MFS_1 PF07690.11 EMR66193.1 - 9.9e-23 80.4 5.8 2.7e-14 52.6 1.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3413 PF11893.3 EMR66193.1 - 0.68 8.7 3.7 0.55 9.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) MIP PF00230.15 EMR66194.1 - 6.2e-49 166.5 14.4 7.7e-49 166.1 10.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein NACHT PF05729.7 EMR66196.1 - 7.1e-12 45.2 1.9 2e-11 43.8 1.3 1.8 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EMR66196.1 - 1.3e-07 31.8 0.0 2.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR66196.1 - 1.9e-07 31.2 0.1 3.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EMR66196.1 - 0.00022 20.2 0.0 0.00097 18.0 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.9 EMR66196.1 - 0.0021 17.1 0.2 0.48 9.3 0.0 2.2 1 1 0 2 2 2 2 KAP family P-loop domain AAA_17 PF13207.1 EMR66196.1 - 0.0034 18.1 0.1 0.015 16.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EMR66196.1 - 0.0036 17.5 0.0 0.0072 16.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 EMR66196.1 - 0.0039 17.0 0.0 0.098 12.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 EMR66196.1 - 0.0048 17.1 0.0 0.027 14.6 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EMR66196.1 - 0.014 14.8 0.1 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EMR66196.1 - 0.021 14.5 0.0 0.056 13.1 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 EMR66196.1 - 0.028 14.7 0.1 0.12 12.7 0.1 2.2 2 1 0 2 2 1 0 AAA domain AAA_19 PF13245.1 EMR66196.1 - 0.028 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EMR66196.1 - 0.03 13.7 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain NTPase_1 PF03266.10 EMR66196.1 - 0.036 13.7 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.17 EMR66196.1 - 0.048 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EMR66196.1 - 0.058 12.7 0.1 0.25 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 EMR66196.1 - 0.074 11.8 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Rad17 PF03215.10 EMR66196.1 - 0.08 11.6 0.0 0.34 9.5 0.0 1.8 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 EMR66196.1 - 0.087 12.7 0.0 0.27 11.2 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 EMR66196.1 - 0.092 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Viral_helicase1 PF01443.13 EMR66196.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 EMR66196.1 - 0.17 10.9 0.0 0.42 9.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin MTHFR PF02219.12 EMR66197.1 - 2.7e-110 368.0 0.0 5.1e-110 367.0 0.0 1.4 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase Peptidase_M20 PF01546.23 EMR66198.1 - 2.5e-24 85.8 0.0 3.8e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMR66198.1 - 6.9e-05 22.5 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMR66198.1 - 8.7e-05 22.3 0.0 0.00025 20.8 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 APH PF01636.18 EMR66199.1 - 2.3e-11 43.9 0.7 3.2e-11 43.4 0.5 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMR66199.1 - 0.035 13.6 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cyclin_N PF00134.18 EMR66200.1 - 5.3e-09 35.7 0.0 1.2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Zn-ribbon_8 PF09723.5 EMR66200.1 - 0.012 15.5 0.3 0.025 14.5 0.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain UQ_con PF00179.21 EMR66201.1 - 1.7e-23 82.6 0.1 2.9e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EMR66201.1 - 0.0016 18.0 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 EMR66201.1 - 0.0062 16.3 0.1 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMR66201.1 - 0.033 14.0 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 RWD domain FluMu_gp41 PF10109.4 EMR66203.1 - 0.086 12.7 0.1 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Mu-like prophage FluMu protein gp41 Ribosomal_L1 PF00687.16 EMR66205.1 - 1.7e-51 174.7 0.1 1.7e-51 174.7 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family F-box-like PF12937.2 EMR66206.1 - 8.3e-05 22.2 0.1 0.00028 20.5 0.1 2.0 1 0 0 1 1 1 1 F-box-like Peptidase_M19 PF01244.16 EMR66207.1 - 2.2e-31 109.0 0.0 8.1e-25 87.4 0.0 2.1 1 1 1 2 2 2 2 Membrane dipeptidase (Peptidase family M19) PTS_2-RNA PF01885.11 EMR66208.1 - 8.9e-17 60.9 0.0 1.4e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 EMR66208.1 - 0.094 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 La domain AA_permease_2 PF13520.1 EMR66209.1 - 1.2e-62 211.8 33.5 1.5e-62 211.5 23.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMR66209.1 - 3.2e-23 81.8 25.1 3.2e-23 81.8 17.4 2.0 2 0 0 2 2 2 2 Amino acid permease Helicase_C PF00271.26 EMR66210.1 - 3.6e-05 23.5 0.0 0.00094 19.0 0.0 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain Ligase_CoA PF00549.14 EMR66210.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 CoA-ligase 2-Hacid_dh_C PF02826.14 EMR66211.1 - 3e-45 153.5 0.0 3.9e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMR66211.1 - 5.2e-10 38.9 0.0 7.7e-10 38.3 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMR66211.1 - 5.6e-05 23.0 0.0 9.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMR66211.1 - 0.008 16.5 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent SIS PF01380.17 EMR66211.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 SIS domain zf-C2H2_4 PF13894.1 EMR66212.1 - 5.6e-10 38.8 17.6 0.0028 17.8 0.6 5.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMR66212.1 - 2.7e-09 36.8 18.2 0.00033 20.7 0.6 4.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type NACHT PF05729.7 EMR66212.1 - 1.1e-08 34.9 0.0 2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain zf-H2C2_2 PF13465.1 EMR66212.1 - 2.4e-06 27.5 25.9 1.1e-05 25.5 0.3 5.6 6 0 0 6 6 5 2 Zinc-finger double domain zf-met PF12874.2 EMR66212.1 - 2.3e-05 24.4 2.1 0.16 12.2 0.1 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type AAA_16 PF13191.1 EMR66212.1 - 7.8e-05 22.7 0.1 0.00088 19.3 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain zf-C2H2_jaz PF12171.3 EMR66212.1 - 8.1e-05 22.6 6.7 0.016 15.3 0.1 3.7 3 0 0 3 3 2 2 Zinc-finger double-stranded RNA-binding AAA_22 PF13401.1 EMR66212.1 - 0.0019 18.3 0.1 0.012 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EMR66212.1 - 0.0026 16.6 0.1 0.019 13.8 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.17 EMR66212.1 - 0.0048 17.0 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase zf-C2H2_6 PF13912.1 EMR66212.1 - 0.017 15.0 9.8 0.049 13.5 0.2 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger AAA_14 PF13173.1 EMR66212.1 - 0.038 13.8 0.1 0.13 12.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EMR66212.1 - 0.065 12.9 0.6 0.16 11.6 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase HypA PF01155.14 EMR66212.1 - 0.12 12.0 0.5 0.26 10.9 0.3 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family AAA_19 PF13245.1 EMR66212.1 - 0.24 11.1 0.0 0.53 10.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain zf-BED PF02892.10 EMR66212.1 - 1.7 8.4 6.3 3.9 7.3 0.5 3.0 1 1 1 2 2 2 0 BED zinc finger p450 PF00067.17 EMR66213.1 - 7.5e-37 126.9 0.0 2.7e-32 111.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Exo_endo_phos PF03372.18 EMR66215.1 - 1.3e-11 44.9 0.2 1.5e-11 44.7 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NmrA PF05368.8 EMR66216.1 - 4e-28 98.2 0.0 3.5e-27 95.1 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR66216.1 - 1.2e-07 31.8 0.2 2e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EMR66216.1 - 0.00025 21.0 0.1 0.0007 19.5 0.0 1.8 1 1 1 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.14 EMR66216.1 - 0.012 14.3 0.1 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMR66216.1 - 0.022 14.1 0.1 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMR66216.1 - 0.12 12.2 0.5 0.29 11.0 0.3 1.7 1 1 0 1 1 1 0 short chain dehydrogenase Ras PF00071.17 EMR66217.1 - 1.6e-59 199.9 0.1 1.8e-59 199.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR66217.1 - 1.2e-18 67.7 0.0 1.8e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMR66217.1 - 1.4e-07 30.8 0.0 1.6e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMR66217.1 - 9.5e-07 28.4 0.1 4e-06 26.3 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMR66217.1 - 0.0018 18.1 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMR66217.1 - 0.0062 15.8 0.0 0.012 14.9 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EMR66217.1 - 0.016 14.3 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 EMR66217.1 - 0.042 13.2 0.9 0.63 9.4 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 EMR66217.1 - 0.062 12.4 0.1 0.14 11.3 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EMR66217.1 - 0.16 11.5 1.4 2.3 7.6 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 EMR66217.1 - 0.17 11.2 0.1 0.29 10.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain DUF3292 PF11696.3 EMR66218.1 - 0.19 9.5 1.1 0.28 9.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Sigma_reg_N PF13800.1 EMR66218.1 - 1.5 8.8 5.8 7.3 6.7 0.1 3.1 3 0 0 3 3 3 0 Sigma factor regulator N-terminal FAD_binding_3 PF01494.14 EMR66220.1 - 9.8e-14 51.1 1.6 9.2e-09 34.8 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR66220.1 - 1.7e-06 27.2 0.5 0.0002 20.3 0.3 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR66220.1 - 0.0006 20.1 0.3 0.003 17.9 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR66220.1 - 0.019 15.0 0.2 0.04 13.9 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EMR66220.1 - 0.073 11.6 0.6 1.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.15 EMR66220.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MoCF_biosynth PF00994.19 EMR66221.1 - 9.7e-17 60.7 0.0 1.8e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain NAD_binding_4 PF07993.7 EMR66222.1 - 8e-37 126.5 0.0 1.1e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EMR66222.1 - 6.2e-24 84.1 0.0 8.8e-23 80.3 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EMR66222.1 - 1.2e-13 51.0 0.0 1.8e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR66222.1 - 3.5e-09 35.7 0.0 6.4e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMR66222.1 - 3.7e-05 23.8 0.2 0.00048 20.1 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMR66222.1 - 0.00013 21.9 0.1 0.0003 20.7 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 EMR66222.1 - 0.00044 20.4 0.2 0.002 18.3 0.1 2.1 1 1 0 1 1 1 1 Phosphopantetheine attachment site Adenylsucc_synt PF00709.16 EMR66223.1 - 3.3e-137 457.5 0.0 4.1e-134 447.3 0.0 2.0 1 1 1 2 2 2 2 Adenylosuccinate synthetase MCD PF05292.6 EMR66223.1 - 0.15 10.7 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase (MCD) Pribosyltran PF00156.22 EMR66224.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain HD_3 PF13023.1 EMR66225.1 - 3.7e-46 156.8 0.0 4.7e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 HD domain Esterase_phd PF10503.4 EMR66226.1 - 1.1e-23 83.6 1.6 1.5e-23 83.1 1.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EMR66226.1 - 8.6e-07 28.3 1.1 1.6e-06 27.4 0.6 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMR66226.1 - 5.1e-06 26.2 0.6 7.4e-06 25.7 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR66226.1 - 0.0076 16.1 3.4 0.011 15.6 1.5 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.23 EMR66226.1 - 0.013 14.2 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR66226.1 - 0.028 13.9 0.1 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold F-box-like PF12937.2 EMR66228.1 - 0.00018 21.1 0.7 0.00035 20.2 0.5 1.5 1 0 0 1 1 1 1 F-box-like Phyto_Pns9_10 PF05878.6 EMR66230.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 NMO PF03060.10 EMR66231.1 - 9.8e-33 113.6 4.5 1.5e-32 113.1 3.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EMR66231.1 - 3.3e-09 36.0 6.6 4.7e-09 35.5 4.6 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EMR66231.1 - 0.00013 21.0 0.1 0.00013 21.0 0.1 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 EMR66231.1 - 0.00045 19.2 0.6 0.00082 18.3 0.4 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain PcrB PF01884.12 EMR66231.1 - 4.6 6.4 5.5 15 4.7 0.6 2.2 2 0 0 2 2 2 0 PcrB family GSDH PF07995.6 EMR66232.1 - 5.1e-08 32.3 0.0 9.6e-08 31.4 0.0 1.5 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NAD_binding_2 PF03446.10 EMR66233.1 - 1.1e-21 77.4 0.3 1.2e-21 77.2 0.2 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase KAP_NTPase PF07693.9 EMR66233.1 - 0.067 12.1 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Shikimate_DH PF01488.15 EMR66233.1 - 0.072 13.1 0.0 0.099 12.7 0.0 1.4 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_71 PF03659.9 EMR66234.1 - 3.8e-132 440.4 0.4 4.4e-132 440.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF218 PF02698.12 EMR66235.1 - 3.1e-07 30.0 0.0 7.7e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 DUF218 domain Mur_ligase_M PF08245.7 EMR66235.1 - 1.7e-05 24.9 0.0 3.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EMR66235.1 - 0.0055 16.7 0.0 0.031 14.2 0.0 2.3 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Sugar_tr PF00083.19 EMR66236.1 - 1.1e-82 278.0 24.7 1.4e-82 277.7 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR66236.1 - 2.4e-29 102.1 35.7 1.4e-23 83.1 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 EMR66236.1 - 0.0049 15.6 9.5 0.01 14.5 6.6 1.5 1 0 0 1 1 1 1 PUCC protein MFS_1_like PF12832.2 EMR66236.1 - 0.0079 15.9 2.1 5.1 6.9 0.0 3.6 3 1 0 3 3 3 2 MFS_1 like family PhyH PF05721.8 EMR66237.1 - 1.6e-20 74.0 0.0 1.9e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aldedh PF00171.17 EMR66238.1 - 5.8e-136 453.4 0.0 6.6e-136 453.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.20 EMR66239.1 - 4.3e-16 59.2 0.3 7.7e-16 58.4 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR66239.1 - 1.9e-08 34.1 0.1 2.9e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR66239.1 - 0.0049 16.6 0.0 0.0073 16.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Toprim_4 PF13662.1 EMR66239.1 - 0.12 12.3 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Toprim domain FHA PF00498.21 EMR66240.1 - 4.4e-09 36.3 0.0 1.1e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 FHA domain Peptidase_M20 PF01546.23 EMR66241.1 - 2.7e-22 79.1 0.2 3.4e-22 78.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMR66241.1 - 1.7e-07 30.9 0.1 3.7e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMR66241.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 Glyco_hydro_71 PF03659.9 EMR66242.1 - 2.1e-128 428.1 4.2 2.4e-128 427.9 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 EMR66242.1 - 0.026 14.2 0.0 0.29 10.8 0.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) AP_endonuc_2 PF01261.19 EMR66242.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Pkinase PF00069.20 EMR66243.1 - 5.9e-54 182.9 0.0 3.6e-45 154.1 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR66243.1 - 1.4e-34 119.3 0.0 1.1e-28 100.0 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMR66243.1 - 8.7e-05 21.6 0.0 0.00082 18.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Ric8 PF10165.4 EMR66243.1 - 0.00024 20.0 0.0 0.00073 18.4 0.0 1.8 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Kdo PF06293.9 EMR66243.1 - 0.13 11.3 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT PF02985.17 EMR66244.1 - 1.4e-10 40.3 5.7 0.14 12.3 0.0 5.5 5 0 0 5 5 5 4 HEAT repeat Pkinase PF00069.20 EMR66244.1 - 1.9e-06 27.2 0.0 3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR66244.1 - 3.1e-06 26.4 0.0 5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EMR66244.1 - 5.7e-05 23.3 0.5 0.016 15.4 0.2 2.9 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 EMR66244.1 - 0.00094 19.5 1.3 1.9 9.0 0.0 4.0 2 2 1 3 3 3 1 HEAT-like repeat FlhE PF06366.8 EMR66244.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein FlhE Kinase-like PF14531.1 EMR66244.1 - 0.03 13.2 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like CLASP_N PF12348.3 EMR66244.1 - 0.033 13.5 0.0 5.2 6.3 0.0 2.5 1 1 1 2 2 2 0 CLASP N terminal Adaptin_N PF01602.15 EMR66244.1 - 0.046 12.0 0.0 0.95 7.6 0.0 2.0 1 1 1 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.2 EMR66244.1 - 0.094 12.5 0.0 0.23 11.2 0.0 1.5 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 FAD_binding_3 PF01494.14 EMR66246.1 - 0.002 17.2 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NmrA PF05368.8 EMR66247.1 - 1.4e-15 57.1 0.0 1.9e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family IFRD PF05004.8 EMR66248.1 - 7.8e-35 120.4 3.3 1e-34 120.0 2.3 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.1 EMR66248.1 - 0.0023 18.3 2.9 3.3 8.3 0.0 4.1 1 1 3 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.1 EMR66248.1 - 0.0062 16.7 2.4 1.7 8.9 0.1 2.6 1 1 2 3 3 3 3 HEAT repeats Citrate_synt PF00285.16 EMR66249.1 - 2.7e-94 315.8 0.0 3.1e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase UvrC_HhH_N PF08459.6 EMR66249.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal LigB PF02900.13 EMR66251.1 - 5.9e-47 159.9 0.0 7.5e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase NmrA PF05368.8 EMR66252.1 - 4.1e-22 78.5 0.0 5.4e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR66252.1 - 6.5e-13 49.0 0.2 4.1e-12 46.4 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMR66252.1 - 0.011 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 KR domain Peripla_BP_6 PF13458.1 EMR66252.1 - 0.045 13.1 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Semialdhyde_dh PF01118.19 EMR66252.1 - 0.083 13.2 0.1 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EMR66252.1 - 0.1 13.0 0.1 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Lipase_GDSL PF00657.17 EMR66253.1 - 7e-14 52.2 0.3 9e-14 51.8 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EMR66253.1 - 2.3e-12 47.3 0.1 3.2e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EMR66253.1 - 0.0028 17.4 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ADH_N PF08240.7 EMR66254.1 - 1.1e-14 54.0 0.3 2.6e-14 52.9 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR66254.1 - 1.3e-13 50.5 0.0 3.5e-08 33.0 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR66254.1 - 1.1e-06 29.5 0.1 3e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EMR66254.1 - 0.0026 17.1 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 EMR66254.1 - 0.0075 16.8 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR66254.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EMR66254.1 - 0.055 12.6 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMR66255.1 - 8.4e-40 135.8 0.0 1.2e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMR66255.1 - 9.1e-22 76.9 0.0 1.1e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 EMR66255.1 - 0.00014 21.7 0.4 0.00028 20.7 0.1 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_10 PF13460.1 EMR66255.1 - 0.048 13.6 1.0 0.08 12.9 0.6 1.4 1 1 0 1 1 1 0 NADH(P)-binding XdhC_C PF13478.1 EMR66255.1 - 0.049 13.9 0.0 0.53 10.5 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain Abhydrolase_5 PF12695.2 EMR66257.1 - 7.4e-08 32.2 0.1 1.2e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR66257.1 - 9.6e-07 28.9 0.2 1.3e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sugar_tr PF00083.19 EMR66258.1 - 4.5e-105 351.8 23.2 5.6e-105 351.5 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR66258.1 - 1.2e-21 76.8 34.5 1.4e-15 56.8 5.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1761 PF08570.5 EMR66258.1 - 7 6.6 16.8 0.028 14.4 2.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1761) WD40 PF00400.27 EMR66260.1 - 2.4e-46 154.0 17.8 5e-11 42.0 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EMR66260.1 - 9.7e-05 20.6 6.4 0.63 8.1 0.1 4.6 4 1 1 5 5 5 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 EMR66260.1 - 0.013 13.7 0.0 0.022 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) HPS3_N PF14761.1 EMR66260.1 - 0.14 11.5 0.0 0.73 9.1 0.0 2.0 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 Nucleoporin_N PF08801.6 EMR66260.1 - 0.15 10.7 3.6 1.1 7.9 1.0 3.0 1 1 1 2 2 2 0 Nup133 N terminal like Glyco_hydro_61 PF03443.9 EMR66261.1 - 5.5e-75 251.9 0.3 5.5e-75 251.9 0.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 DUF3403 PF11883.3 EMR66261.1 - 0.019 15.2 1.8 0.24 11.6 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) SOBP PF15279.1 EMR66261.1 - 0.34 11.2 6.0 0.51 10.6 4.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF1326 PF07040.6 EMR66262.1 - 0.14 11.9 0.1 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) Fungal_trans PF04082.13 EMR66263.1 - 1.7e-10 40.2 0.0 2.3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EMR66264.1 - 3.1e-21 75.4 0.3 6.2e-21 74.4 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR66264.1 - 0.028 14.3 1.5 0.052 13.4 1.0 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EMR66265.1 - 6.9e-33 113.8 27.9 9.3e-33 113.3 19.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3814 PF12769.2 EMR66265.1 - 0.033 14.3 5.3 0.047 13.8 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3814) Sec62 PF03839.11 EMR66265.1 - 0.2 11.0 0.4 0.57 9.5 0.0 1.8 2 0 0 2 2 2 0 Translocation protein Sec62 GHMP_kinases_N PF00288.21 EMR66267.1 - 8.7e-13 48.1 0.0 2.2e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMR66267.1 - 1.4e-05 25.2 0.0 3.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal FAD_binding_4 PF01565.18 EMR66268.1 - 3.7e-24 84.7 0.3 6.9e-24 83.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_4 PF01565.18 EMR66269.1 - 1.8e-17 63.1 0.3 3.2e-17 62.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR66269.1 - 0.00014 21.6 0.3 0.00032 20.5 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Aldolase_II PF00596.16 EMR66270.1 - 5.1e-50 169.6 0.2 6.3e-50 169.3 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PLAC8 PF04749.12 EMR66271.1 - 1.4e-20 73.8 15.1 1.7e-20 73.5 10.4 1.1 1 0 0 1 1 1 1 PLAC8 family ThiF PF00899.16 EMR66273.1 - 8e-12 45.1 0.0 1.8e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 ThiF family Delta_lysin PF05372.6 EMR66273.1 - 7.6 5.9 6.1 3.6 7.0 1.0 2.7 3 0 0 3 3 3 0 Delta lysin family Methyltransf_3 PF01596.12 EMR66274.1 - 6.5e-29 100.4 0.1 1.6e-14 53.4 0.0 2.0 2 0 0 2 2 2 2 O-methyltransferase Methyltransf_24 PF13578.1 EMR66274.1 - 4.2e-09 37.1 0.0 7.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR66274.1 - 7.2e-06 26.5 0.1 1.5e-05 25.5 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR66274.1 - 0.0043 17.0 1.0 0.0098 15.9 0.5 1.7 1 1 0 1 1 1 1 Methyltransferase domain NST1 PF13945.1 EMR66276.1 - 0.029 14.4 4.0 0.045 13.8 2.8 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator VID27 PF08553.5 EMR66277.1 - 0 1133.9 0.0 0 1133.6 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein FAD_binding_3 PF01494.14 EMR66279.1 - 2.1e-10 40.1 0.0 2.5e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_4 PF01565.18 EMR66280.1 - 1.4e-21 76.4 0.1 2.7e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR66280.1 - 0.0018 18.1 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans_2 PF11951.3 EMR66281.1 - 3.3e-19 68.7 0.2 1e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain SNF2_N PF00176.18 EMR66282.1 - 4.8e-58 196.3 0.0 1.2e-57 195.0 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMR66282.1 - 1.7e-11 43.8 0.0 3.5e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR66282.1 - 0.00044 20.1 0.0 0.00089 19.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NMO PF03060.10 EMR66283.1 - 7.8e-27 94.2 0.1 1.2e-26 93.6 0.1 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EMR66283.1 - 2.7e-05 23.2 0.0 3.6e-05 22.8 0.0 1.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain adh_short PF00106.20 EMR66284.1 - 1.4e-26 93.3 0.0 1.8e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR66284.1 - 3.9e-26 92.3 0.0 5e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR66284.1 - 4.8e-11 42.6 0.0 6.2e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMR66284.1 - 6.5e-05 22.6 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EMR66284.1 - 0.003 17.0 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMR66284.1 - 0.0094 14.8 0.1 0.057 12.3 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DUF1776 PF08643.5 EMR66284.1 - 0.023 13.8 0.0 0.039 13.0 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_7 PF13241.1 EMR66284.1 - 0.024 14.8 0.1 0.04 14.1 0.1 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 EMR66285.1 - 9.6e-46 155.1 0.0 1.3e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMR66285.1 - 0.0013 18.2 0.0 0.0051 16.2 0.0 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_10 PF13460.1 EMR66285.1 - 0.0014 18.7 0.5 0.0039 17.2 0.2 1.8 2 0 0 2 2 2 1 NADH(P)-binding XdhC_C PF13478.1 EMR66285.1 - 0.0024 18.1 0.0 0.006 16.9 0.0 1.6 2 0 0 2 2 2 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.16 EMR66285.1 - 0.0029 17.4 0.0 0.0078 16.0 0.0 1.6 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ELFV_dehydrog PF00208.16 EMR66285.1 - 0.16 11.4 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MFS_1 PF07690.11 EMR66286.1 - 9.9e-24 83.6 15.6 2.9e-23 82.1 10.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Syndecan PF01034.15 EMR66286.1 - 0.019 14.6 0.1 0.046 13.3 0.1 1.6 1 0 0 1 1 1 0 Syndecan domain DUF4381 PF14316.1 EMR66286.1 - 0.093 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) AMP-binding PF00501.23 EMR66287.1 - 1.7e-83 280.3 0.0 2.6e-83 279.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EMR66287.1 - 1.3e-25 89.8 0.0 5.3e-20 71.4 0.0 2.4 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EMR66287.1 - 2.9e-08 33.8 0.0 6.2e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site HET PF06985.6 EMR66288.1 - 1.6e-07 31.5 0.0 2.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EMR66289.1 - 1.2e-08 35.2 0.0 1.7e-07 31.4 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMR66289.1 - 7.3e-08 31.8 0.1 0.00025 20.7 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 EMR66289.1 - 1.2e-05 25.0 0.1 0.016 15.4 0.0 3.9 2 1 1 3 3 3 1 Ankyrin repeat F-box-like PF12937.2 EMR66289.1 - 2.5e-05 23.9 0.1 9.1e-05 22.1 0.1 1.9 2 0 0 2 2 2 1 F-box-like Ank_5 PF13857.1 EMR66289.1 - 0.00012 22.1 0.0 0.011 15.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR66289.1 - 0.0028 18.1 0.0 0.11 13.0 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) DUF2690 PF10901.3 EMR66289.1 - 0.055 13.4 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2690) MFS_1 PF07690.11 EMR66291.1 - 5.1e-20 71.4 12.4 6.3e-17 61.3 4.0 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily O-antigen_lig PF13425.1 EMR66291.1 - 9.4 6.2 13.8 3.7 7.5 1.3 3.4 2 1 0 3 3 3 0 O-antigen ligase like membrane protein PdxA PF04166.7 EMR66292.1 - 6.6e-79 265.2 0.0 8.2e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Fungal_trans PF04082.13 EMR66293.1 - 1.2e-08 34.1 1.0 3.4e-08 32.6 0.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR66293.1 - 0.00033 20.4 9.9 0.00059 19.6 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EMR66294.1 - 8.7e-35 120.0 57.2 3.4e-34 118.0 35.2 3.3 2 1 0 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.14 EMR66294.1 - 2.5e-08 32.9 0.4 2.5e-08 32.9 0.3 2.6 3 0 0 3 3 3 1 LacY proton/sugar symporter CcmD PF04995.9 EMR66294.1 - 0.38 10.5 2.9 0.87 9.3 0.8 2.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) AAA PF00004.24 EMR66295.1 - 3.2e-32 111.4 0.1 1.9e-13 50.7 0.0 4.7 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMR66295.1 - 7e-12 46.2 7.9 0.00011 23.0 0.0 5.3 4 2 0 4 4 4 2 AAA domain AAA_5 PF07728.9 EMR66295.1 - 2.5e-11 43.4 0.1 0.0081 15.8 0.0 4.2 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMR66295.1 - 3.5e-11 43.3 1.8 0.01 15.9 0.0 6.1 5 3 0 6 6 6 2 AAA domain RuvB_N PF05496.7 EMR66295.1 - 2.2e-09 36.7 0.0 0.011 14.8 0.0 4.8 5 1 0 5 5 4 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMR66295.1 - 1.5e-08 34.2 0.1 0.0015 18.2 0.1 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 EMR66295.1 - 2.5e-07 30.6 0.2 0.046 13.6 0.0 3.9 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.1 EMR66295.1 - 8.2e-07 29.3 7.9 0.023 14.9 0.0 4.7 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.1 EMR66295.1 - 3.1e-06 27.3 0.1 0.037 13.9 0.0 3.9 3 0 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.17 EMR66295.1 - 5.7e-06 26.4 0.1 0.17 12.0 0.0 3.8 4 0 0 4 4 3 2 RNA helicase Torsin PF06309.6 EMR66295.1 - 8.2e-06 25.7 0.0 0.92 9.4 0.0 3.9 3 0 0 3 3 3 2 Torsin Mg_chelatase PF01078.16 EMR66295.1 - 1.1e-05 24.6 0.0 0.22 10.6 0.0 3.2 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EMR66295.1 - 1.8e-05 24.3 1.6 0.049 13.0 0.0 3.4 3 1 0 3 3 2 2 AAA-like domain IstB_IS21 PF01695.12 EMR66295.1 - 1.8e-05 24.2 0.0 0.13 11.7 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_24 PF13479.1 EMR66295.1 - 3.3e-05 23.5 0.1 0.19 11.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EMR66295.1 - 0.00023 21.1 0.2 0.65 9.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EMR66295.1 - 0.0003 20.4 1.4 0.5 9.9 0.1 4.2 4 1 0 4 4 4 1 AAA domain MobB PF03205.9 EMR66295.1 - 0.00044 19.9 0.1 0.22 11.2 0.0 3.4 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EMR66295.1 - 0.00074 19.0 0.0 0.32 10.4 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 EMR66295.1 - 0.0052 15.9 0.0 1.2 8.1 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.21 EMR66295.1 - 0.006 16.0 0.0 12 5.3 0.0 4.1 5 0 0 5 5 4 0 Sigma-54 interaction domain KTI12 PF08433.5 EMR66295.1 - 0.0062 15.7 0.0 2.6 7.1 0.0 2.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 SRP54 PF00448.17 EMR66295.1 - 0.0079 15.6 0.1 4.5 6.6 0.0 3.1 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain tRNA_lig_kinase PF08303.6 EMR66295.1 - 0.027 14.3 0.0 6.9 6.5 0.0 2.6 2 0 0 2 2 2 0 tRNA ligase kinase domain DUF258 PF03193.11 EMR66295.1 - 0.03 13.5 0.1 2.2 7.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_11 PF13086.1 EMR66295.1 - 0.033 13.7 0.4 3.2 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 EMR66295.1 - 0.036 13.7 0.4 1 9.0 0.1 2.8 2 0 0 2 2 2 0 NTPase SKI PF01202.17 EMR66295.1 - 0.059 13.2 0.0 19 5.0 0.0 3.3 3 0 0 3 3 3 0 Shikimate kinase AAA_25 PF13481.1 EMR66295.1 - 0.084 12.2 0.2 5.3 6.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_3 PF07726.6 EMR66295.1 - 0.091 12.3 0.0 9.8 5.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EMR66295.1 - 0.14 11.7 0.5 18 4.9 0.0 3.3 3 1 1 4 4 4 0 NACHT domain ABC_tran PF00005.22 EMR66295.1 - 0.22 11.8 4.2 2.1 8.6 0.0 4.0 4 1 0 4 4 3 0 ABC transporter DUF1282 PF06930.7 EMR66296.1 - 0.0016 18.1 0.1 0.0018 17.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Yip1 PF04893.12 EMR66296.1 - 0.026 14.0 0.6 0.03 13.8 0.4 1.1 1 0 0 1 1 1 0 Yip1 domain DUF4064 PF13273.1 EMR66296.1 - 0.064 13.3 1.3 0.29 11.2 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF3810 PF12725.2 EMR66296.1 - 0.16 10.8 0.1 0.2 10.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) TMEMspv1-c74-12 PF11044.3 EMR66296.1 - 1 8.9 4.6 1.2 8.7 0.1 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein MACPF PF01823.14 EMR66297.1 - 0.075 12.7 0.3 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 MAC/Perforin domain zf-B_box PF00643.19 EMR66297.1 - 0.13 12.2 7.0 4.4 7.2 1.4 2.9 2 0 0 2 2 2 0 B-box zinc finger FYVE PF01363.16 EMR66297.1 - 2.8 7.8 13.4 0.03 14.2 2.9 2.4 2 1 0 2 2 2 0 FYVE zinc finger DUF1712 PF08217.6 EMR66298.1 - 2.7e-11 42.4 0.0 2.5e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) He_PIG PF05345.7 EMR66299.1 - 5.6e-12 45.4 14.0 0.0018 18.2 0.2 5.4 5 0 0 5 5 5 4 Putative Ig domain Herpes_gE PF02480.11 EMR66299.1 - 0.22 9.7 0.0 0.38 8.9 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 EMR66299.1 - 0.3 10.7 0.0 0.3 10.7 0.0 2.6 3 0 0 3 3 3 0 TMEM154 protein family ICL PF00463.16 EMR66300.1 - 3.6e-278 923.0 0.3 4.1e-278 922.8 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EMR66300.1 - 2.4e-12 46.6 0.3 4.5e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DPBB_1 PF03330.13 EMR66301.1 - 0.0003 20.7 0.0 0.00062 19.7 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel PAT1 PF09770.4 EMR66301.1 - 0.74 7.9 10.9 0.95 7.6 7.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAP PF07174.6 EMR66301.1 - 4.1 6.6 28.9 9.3 5.4 20.0 1.6 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF605 PF04652.11 EMR66301.1 - 4.7 6.5 21.2 5.8 6.1 14.7 1.2 1 0 0 1 1 1 0 Vta1 like RNA_Me_trans PF04252.8 EMR66302.1 - 2.7e-45 154.2 0.0 3.3e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase adh_short PF00106.20 EMR66303.1 - 6.7e-23 81.4 0.4 3.9e-22 78.9 0.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR66303.1 - 8.1e-13 48.6 0.0 3.4e-12 46.6 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR66303.1 - 1e-08 35.0 1.3 1.2e-08 34.8 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EMR66303.1 - 0.022 14.1 0.1 0.2 11.0 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR66303.1 - 0.077 13.0 0.4 0.18 11.8 0.1 1.8 2 1 0 2 2 2 0 NADH(P)-binding Yippee-Mis18 PF03226.9 EMR66304.1 - 3.6e-17 62.1 0.0 5.4e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Methyltransf_16 PF10294.4 EMR66305.1 - 5.8e-23 81.2 0.0 6.8e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Pro_isomerase PF00160.16 EMR66306.1 - 4.8e-44 150.2 0.2 7.6e-44 149.6 0.2 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EMR66306.1 - 3.3e-06 26.6 9.6 0.0076 15.8 1.3 2.5 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EMR66306.1 - 6.5e-05 22.5 10.9 0.00011 21.8 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMR66306.1 - 0.00054 19.4 0.1 0.00054 19.4 0.1 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMR66306.1 - 0.0088 15.7 0.2 0.064 13.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMR66306.1 - 0.021 14.7 6.4 0.023 14.6 1.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMR66306.1 - 0.048 14.2 2.0 0.048 14.2 1.4 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMR66306.1 - 0.079 13.4 0.2 0.079 13.4 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMR66306.1 - 0.43 10.4 7.9 0.21 11.4 3.8 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M20 PF01546.23 EMR66307.1 - 1.7e-33 115.7 0.1 4.4e-33 114.3 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMR66307.1 - 8.3e-13 48.0 0.0 1.5e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain RasGAP PF00616.14 EMR66308.1 - 1.4e-16 60.7 0.6 9.2e-14 51.5 0.0 3.2 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EMR66308.1 - 0.012 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 C2 domain CaM-KIIN PF15170.1 EMR66308.1 - 0.016 15.2 0.0 7.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Calcium/calmodulin-dependent protein kinase II inhibitor Gmad2 PF10648.4 EMR66308.1 - 0.16 12.1 0.0 4.3 7.5 0.0 2.5 3 0 0 3 3 3 0 Immunoglobulin-like domain of bacterial spore germination Sugar_tr PF00083.19 EMR66309.1 - 1.6e-87 293.9 21.0 2e-87 293.6 14.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR66309.1 - 2.6e-24 85.6 27.2 4.2e-17 61.8 4.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR66309.1 - 0.016 13.4 7.0 0.022 12.9 0.5 2.4 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Tyr_Deacylase PF02580.11 EMR66310.1 - 4e-46 156.5 0.3 4.7e-46 156.3 0.2 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Glyco_trans_2_3 PF13632.1 EMR66311.1 - 2.3e-44 151.4 2.8 2.3e-44 151.4 1.9 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMR66311.1 - 5.4e-08 32.9 0.1 6.3e-07 29.4 0.1 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMR66311.1 - 2.8e-05 23.8 0.0 0.00018 21.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMR66311.1 - 0.0028 16.9 0.0 0.007 15.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF2561 PF10812.3 EMR66311.1 - 0.019 14.5 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) TFIIIC_sub6 PF10419.4 EMR66313.1 - 8e-10 38.0 0.0 1.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit API5 PF05918.6 EMR66313.1 - 0.024 13.1 0.3 0.041 12.4 0.2 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Gly-rich_Ago1 PF12764.2 EMR66313.1 - 0.72 10.5 3.9 0.54 10.9 0.7 2.1 2 0 0 2 2 2 0 Glycine-rich region of argonaut Ino80_Iec3 PF14612.1 EMR66314.1 - 6.3e-55 186.7 13.7 6.3e-31 108.2 3.0 2.6 2 1 1 3 3 3 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling CDK2AP PF09806.4 EMR66314.1 - 0.043 14.0 2.3 0.088 13.0 1.6 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2201_N PF13203.1 EMR66314.1 - 0.33 10.0 12.5 0.28 10.2 7.0 1.9 2 0 0 2 2 2 0 Putative metallopeptidase domain Not3 PF04065.10 EMR66315.1 - 8.3e-100 332.8 25.9 8.3e-100 332.8 17.9 1.6 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EMR66315.1 - 4.6e-41 139.8 10.0 4.6e-41 139.8 6.9 2.2 1 1 1 2 2 2 1 NOT2 / NOT3 / NOT5 family Cep57_MT_bd PF06657.8 EMR66315.1 - 0.0033 17.3 6.9 0.026 14.4 0.7 3.0 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 DUF2373 PF10180.4 EMR66315.1 - 0.0048 16.4 4.0 0.01 15.3 2.8 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.6 EMR66315.1 - 0.031 14.0 1.6 0.031 14.0 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Snapin_Pallidin PF14712.1 EMR66315.1 - 0.06 13.6 12.0 0.096 12.9 0.3 2.8 2 1 0 2 2 2 0 Snapin/Pallidin Syntaxin PF00804.20 EMR66315.1 - 1.3 9.2 18.4 0.2 11.8 4.8 2.8 3 0 0 3 3 3 0 Syntaxin MMPL PF03176.10 EMR66315.1 - 1.4 7.5 3.5 2.7 6.6 2.4 1.5 1 1 0 1 1 1 0 MMPL family CorA PF01544.13 EMR66315.1 - 2 7.3 6.2 0.95 8.4 0.3 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Poty_PP PF08440.5 EMR66315.1 - 2.5 7.0 8.2 0.13 11.3 1.2 2.0 3 0 0 3 3 3 0 Potyviridae polyprotein Sec5 PF15469.1 EMR66315.1 - 2.7 7.6 12.7 0.95 9.1 1.8 2.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 LMBR1 PF04791.11 EMR66315.1 - 3.5 6.1 5.3 4 5.9 3.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3810 PF12725.2 EMR66315.1 - 3.6 6.4 9.4 2.7 6.8 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) Trehalase PF01204.13 EMR66316.1 - 4.4e-191 635.9 0.0 5.5e-191 635.6 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EMR66316.1 - 3.6e-17 61.3 0.6 5.8e-17 60.7 0.4 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF1680 PF07944.7 EMR66317.1 - 7.1e-104 347.9 1.6 1.1e-48 165.8 0.1 3.4 3 1 0 3 3 3 3 Putative glycosyl hydrolase of unknown function (DUF1680) MRP-L20 PF12824.2 EMR66318.1 - 1.2e-53 181.4 9.2 1.4e-53 181.1 6.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 EMR66318.1 - 0.0018 18.1 0.1 0.0018 18.1 0.1 1.6 2 0 0 2 2 2 1 Neugrin CAF-1_p150 PF11600.3 EMR66318.1 - 0.069 12.5 7.5 0.013 14.8 2.5 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PPR_2 PF13041.1 EMR66319.1 - 6.4e-05 22.8 0.0 0.026 14.5 0.0 3.8 2 1 1 3 3 3 1 PPR repeat family PPR_3 PF13812.1 EMR66319.1 - 0.13 12.5 3.4 4.9 7.6 0.0 4.4 5 0 0 5 5 5 0 Pentatricopeptide repeat domain ODC_AZ PF02100.12 EMR66320.1 - 2.9e-27 94.2 0.0 5.5e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme PP2C PF00481.16 EMR66321.1 - 3.1e-82 275.7 0.0 4.6e-82 275.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMR66321.1 - 0.00057 19.3 0.1 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C His_biosynth PF00977.16 EMR66322.1 - 6.1e-42 143.4 1.2 2.3e-40 138.2 0.8 3.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EMR66322.1 - 5.8e-27 94.4 0.0 8.8e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EMR66322.1 - 8.3e-09 35.3 0.0 4.2e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EMR66322.1 - 7.3e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EMR66322.1 - 0.026 13.9 0.1 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 Dus PF01207.12 EMR66322.1 - 0.086 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) BPL_N PF09825.4 EMR66322.1 - 0.12 11.1 0.0 0.39 9.4 0.0 1.8 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal DUF946 PF06101.6 EMR66323.1 - 8.1e-11 40.6 0.2 1.6e-10 39.6 0.2 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) LSM PF01423.17 EMR66324.1 - 3.7e-15 55.2 0.4 5.2e-15 54.7 0.3 1.2 1 0 0 1 1 1 1 LSM domain NAD_binding_10 PF13460.1 EMR66325.1 - 1e-05 25.6 0.0 4.7e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMR66325.1 - 0.0028 16.5 0.0 1.3 7.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein DapB_N PF01113.15 EMR66325.1 - 0.023 14.5 0.0 0.074 12.9 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EMR66325.1 - 0.11 11.9 0.3 0.83 9.0 0.1 2.4 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EMR66325.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain WD40 PF00400.27 EMR66326.1 - 3.2e-46 153.6 21.9 4.9e-09 35.7 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EMR66326.1 - 7.2e-05 22.5 0.9 0.016 14.9 0.2 2.9 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EMR66326.1 - 0.046 12.4 0.5 0.61 8.7 0.2 2.4 2 1 0 2 2 2 0 Nup133 N terminal like MBOAT PF03062.14 EMR66327.1 - 6.8e-21 74.7 12.9 9.9e-21 74.1 8.6 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EMR66327.1 - 0.0015 18.5 1.2 0.0043 17.1 0.8 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family HRXXH PF13933.1 EMR66328.1 - 4.6e-104 347.2 0.0 6.1e-104 346.7 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family HCV_NS5a_1a PF08300.8 EMR66328.1 - 0.11 12.4 0.7 0.26 11.2 0.5 1.6 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain Podoplanin PF05808.6 EMR66328.1 - 6.6 6.2 7.3 7.6 6.0 3.2 2.0 2 0 0 2 2 2 0 Podoplanin ATP13 PF12921.2 EMR66329.1 - 2e-14 53.0 0.0 5.3e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial ATPase expression Glyco_hydro_28 PF00295.12 EMR66331.1 - 6.3e-47 160.1 12.6 9.6e-47 159.5 8.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EMR66331.1 - 1.4 8.6 23.1 22 4.7 15.5 2.9 1 1 0 1 1 1 0 Right handed beta helix region Kp4 PF09044.5 EMR66332.1 - 6e-21 74.5 4.0 6.8e-21 74.4 2.7 1.0 1 0 0 1 1 1 1 Kp4 DUF3464 PF11947.3 EMR66333.1 - 0.0032 16.9 0.0 0.004 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3464) ORC6 PF05460.8 EMR66333.1 - 0.054 12.6 0.1 0.057 12.5 0.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PIG-L PF02585.12 EMR66334.1 - 5e-25 88.4 0.0 9.1e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF1242 PF06842.7 EMR66334.1 - 0.15 11.5 0.8 0.31 10.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) Ribonuclease_T2 PF00445.13 EMR66335.1 - 8.3e-42 142.9 0.8 1.4e-41 142.1 0.6 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family HATPase_c PF02518.21 EMR66336.1 - 2.1e-24 85.4 0.0 4.1e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMR66336.1 - 1e-21 76.9 0.1 2.6e-21 75.7 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EMR66336.1 - 6.1e-15 55.4 0.1 2.7e-05 24.4 0.0 4.2 3 1 1 4 4 4 3 PAS domain PAS_8 PF13188.1 EMR66336.1 - 5.4e-11 41.9 0.0 0.00042 20.0 0.0 4.5 4 0 0 4 4 4 2 PAS domain PAS_4 PF08448.5 EMR66336.1 - 1.1e-08 35.0 0.0 0.071 13.1 0.0 4.7 4 0 0 4 4 4 2 PAS fold HisKA PF00512.20 EMR66336.1 - 2.6e-07 30.5 0.1 1.7e-06 27.9 0.0 2.5 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 EMR66336.1 - 1.1e-06 28.3 0.1 0.062 13.0 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.6 EMR66336.1 - 7.8e-06 25.9 0.0 0.0055 16.7 0.0 2.8 2 0 0 2 2 2 2 PAS fold HATPase_c_3 PF13589.1 EMR66336.1 - 0.0035 16.9 0.0 0.013 15.1 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.1 EMR66336.1 - 0.055 13.5 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 GAF domain Ank_2 PF12796.2 EMR66337.1 - 3.8e-17 62.4 8.5 3.8e-08 33.5 1.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMR66337.1 - 6.1e-13 47.8 11.7 1.3e-06 27.9 1.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EMR66337.1 - 1.5e-10 40.9 5.7 2.7e-05 24.2 2.0 4.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR66337.1 - 1.8e-10 40.0 10.6 0.0016 18.4 0.2 5.6 4 1 1 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EMR66337.1 - 5.4e-08 33.1 8.6 0.00019 21.8 0.5 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) FlhD PF05247.8 EMR66337.1 - 0.087 12.8 0.3 2.6 8.1 0.1 2.3 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhD) SnoaL_4 PF13577.1 EMR66338.1 - 1.7e-19 69.9 0.0 2.2e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 EMR66338.1 - 5.9e-06 26.8 0.0 7.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Putative lumazine-binding DUF1831 PF08866.5 EMR66338.1 - 0.0012 19.0 0.1 0.0017 18.5 0.0 1.1 1 0 0 1 1 1 1 Putative amino acid metabolism SnoaL_2 PF12680.2 EMR66338.1 - 0.0074 16.6 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EMR66338.1 - 0.031 14.4 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Methyltransf_6 PF03737.10 EMR66339.1 - 0.0002 21.2 0.1 0.00035 20.4 0.0 1.4 2 0 0 2 2 2 1 Demethylmenaquinone methyltransferase Antitoxin-MazE PF04014.13 EMR66339.1 - 0.06 13.0 0.1 2.2 8.1 0.0 2.2 1 1 1 2 2 2 0 Antidote-toxin recognition MazE Dabb PF07876.7 EMR66341.1 - 2.5e-09 37.4 0.0 9.1e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Peptidase_S58 PF03576.9 EMR66341.1 - 0.0087 15.2 0.0 0.01 15.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S58 DAO PF01266.19 EMR66342.1 - 6.3e-44 150.3 2.7 7.6e-44 150.0 1.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HSP70 PF00012.15 EMR66343.1 - 2.2e-266 884.6 16.6 2.5e-266 884.4 11.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMR66343.1 - 3.3e-16 58.8 4.3 3.3e-14 52.2 0.9 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EMR66343.1 - 0.00027 20.6 0.0 0.00068 19.2 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DnaG_DnaB_bind PF08278.6 EMR66343.1 - 0.22 11.7 2.4 0.77 9.9 1.7 2.0 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding DUF4363 PF14276.1 EMR66343.1 - 0.23 11.1 4.1 0.52 10.0 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Hydantoinase_A PF01968.13 EMR66343.1 - 1.4 7.9 7.2 1.3 8.0 0.0 3.1 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase MFS_1 PF07690.11 EMR66344.1 - 4.6e-13 48.5 1.1 6.9e-13 48.0 0.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TPR_7 PF13176.1 EMR66344.1 - 0.0015 18.1 0.3 0.041 13.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR66344.1 - 0.012 15.9 1.3 4.2 7.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMR66344.1 - 0.23 12.1 5.7 19 6.0 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMR66344.1 - 0.34 10.9 1.4 37 4.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMR66344.1 - 4.4 8.2 14.7 6.9 7.6 0.4 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMR66344.1 - 4.8 7.9 11.8 0.35 11.4 3.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat V-ATPase_H_N PF03224.9 EMR66345.1 - 2.1e-73 247.1 0.0 2.5e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EMR66345.1 - 2.7e-38 130.5 0.0 8.3e-38 128.9 0.0 1.9 1 0 0 1 1 1 1 V-ATPase subunit H HEAT_2 PF13646.1 EMR66345.1 - 0.029 14.6 1.1 0.55 10.5 0.0 3.1 2 2 0 2 2 2 0 HEAT repeats HEAT PF02985.17 EMR66345.1 - 0.083 13.0 0.0 1.1 9.5 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat Cu-oxidase_2 PF07731.9 EMR66346.1 - 5.7e-16 58.2 10.5 8e-13 48.0 0.6 2.8 2 1 1 3 3 3 2 Multicopper oxidase adh_short PF00106.20 EMR66347.1 - 6.9e-20 71.6 2.6 1.1e-19 70.9 1.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR66347.1 - 5.6e-10 39.3 0.1 1.2e-09 38.3 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR66347.1 - 7.3e-06 25.7 2.1 2.3e-05 24.1 1.5 1.9 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMR66347.1 - 0.0066 15.6 0.0 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EMR66347.1 - 0.14 11.3 0.0 0.3 10.3 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family Glyco_hydro_1 PF00232.13 EMR66348.1 - 6.4e-75 252.0 0.9 8.2e-73 245.1 0.6 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 EMR66348.1 - 0.00061 19.2 0.1 0.0028 17.0 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core Inositol_P PF00459.20 EMR66350.1 - 7.5e-52 176.2 1.6 1.3e-51 175.4 1.1 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family RCC1 PF00415.13 EMR66351.1 - 5.6e-60 199.3 0.5 8.7e-10 38.6 0.0 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMR66351.1 - 4.9e-35 118.3 23.0 2.9e-07 29.9 0.3 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Bd3614_N PF14442.1 EMR66351.1 - 0.052 13.5 1.9 0.12 12.3 1.3 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal CN_hydrolase PF00795.17 EMR66353.1 - 2.2e-28 98.8 0.0 2.9e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Tht1 PF04163.7 EMR66354.1 - 1.1e-07 30.6 0.3 1.8e-07 29.9 0.2 1.3 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein Cid2 PF09774.4 EMR66354.1 - 0.049 13.7 0.2 0.079 13.0 0.1 1.3 1 0 0 1 1 1 0 Caffeine-induced death protein 2 DUF1351 PF07083.6 EMR66354.1 - 0.053 13.1 0.3 0.078 12.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) NPV_P10 PF05531.7 EMR66354.1 - 0.082 13.1 0.2 0.17 12.1 0.2 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF3482 PF11981.3 EMR66354.1 - 0.11 11.6 0.3 0.15 11.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Rap1_C PF11626.3 EMR66355.1 - 1.3e-22 79.4 0.7 2.8e-22 78.4 0.3 1.7 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EMR66355.1 - 3.1e-08 33.2 2.4 3.6e-08 33.0 0.0 2.4 2 0 0 2 2 2 1 Rap1 Myb domain ARID PF01388.16 EMR66355.1 - 0.0025 17.6 0.7 0.0062 16.3 0.0 1.9 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain E1-E2_ATPase PF00122.15 EMR66356.1 - 1.3e-47 161.7 0.1 2.6e-47 160.7 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMR66356.1 - 7.8e-34 117.9 2.0 2.4e-28 100.0 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMR66356.1 - 1.9e-14 54.3 0.0 5.1e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EMR66356.1 - 9.2e-10 38.5 0.1 7.4e-09 35.6 0.0 2.4 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EMR66356.1 - 0.00018 21.1 1.3 0.0018 17.8 1.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2675 PF11247.3 EMR66356.1 - 0.1 12.7 0.1 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2675) HAD_2 PF13419.1 EMR66356.1 - 0.16 12.2 0.0 0.4 10.8 0.0 1.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Ribosomal_L6 PF00347.18 EMR66357.1 - 9.1e-20 70.9 0.0 6.3e-11 42.6 0.0 3.3 3 1 0 3 3 3 2 Ribosomal protein L6 zf-C3HC PF07967.8 EMR66358.1 - 4e-42 143.1 0.2 2.6e-36 124.3 0.1 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EMR66358.1 - 1.2e-27 95.5 4.4 2.8e-27 94.3 0.0 2.6 2 1 0 2 2 2 1 Rsm1-like BIR PF00653.16 EMR66358.1 - 2.2e-05 24.7 0.1 0.0014 19.0 0.1 2.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain PAP_assoc PF03828.14 EMR66359.1 - 1.3e-14 53.8 0.0 2.7e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EMR66359.1 - 5.3e-09 36.3 0.0 9.8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF1777 PF08648.7 EMR66359.1 - 0.00021 21.1 14.5 0.00044 20.0 10.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) zf-DHHC PF01529.15 EMR66360.1 - 5.5e-33 113.8 0.2 9.5e-33 113.0 0.1 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase FAD_binding_1 PF00667.15 EMR66361.1 - 4.8e-60 202.7 0.0 1.3e-59 201.3 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 EMR66361.1 - 2.6e-10 40.8 0.0 7.1e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 EMR66361.1 - 4.1e-06 26.8 0.0 9.1e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EMR66361.1 - 0.022 14.6 0.4 0.063 13.2 0.3 1.7 1 0 0 1 1 1 0 Transketolase, C-terminal domain NRDE PF05742.7 EMR66362.1 - 1.1e-40 139.7 0.0 1.5e-39 135.9 0.0 1.9 1 1 0 1 1 1 1 NRDE protein APG12 PF04110.8 EMR66363.1 - 3.5e-24 84.8 0.0 4.9e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EMR66363.1 - 0.0023 17.8 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Tfb2 PF03849.9 EMR66364.1 - 4.1e-26 91.4 0.6 1.7e-25 89.4 0.3 1.8 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EMR66364.1 - 1.2e-06 28.2 0.1 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 EMR66364.1 - 0.0041 16.5 0.0 0.016 14.6 0.0 2.0 2 0 0 2 2 2 1 Anti-repressor SinI p450 PF00067.17 EMR66365.1 - 2.7e-43 148.1 0.0 3.5e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.9 EMR66366.1 - 2.9e-31 108.6 6.7 3.6e-31 108.3 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pantoate_transf PF02548.10 EMR66367.1 - 2.4e-101 338.2 0.2 2.7e-101 338.0 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EMR66367.1 - 2.4e-09 36.7 0.6 3.4e-09 36.2 0.4 1.4 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase dCMP_cyt_deam_1 PF00383.17 EMR66368.1 - 3.8e-08 32.9 0.0 8.9e-08 31.7 0.0 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EMR66368.1 - 0.0066 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Bd3614-like deaminase DUF4603 PF15376.1 EMR66368.1 - 0.12 9.5 1.7 0.15 9.2 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) SseC PF04888.7 EMR66370.1 - 0.55 9.5 5.3 0.62 9.3 3.6 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Glycoprotein_B PF00606.13 EMR66370.1 - 0.67 7.9 2.2 0.67 7.9 1.6 1.2 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Peptidase_S3 PF00944.14 EMR66370.1 - 1.5 8.2 4.4 1.5 8.1 2.7 1.3 1 1 0 1 1 1 0 Alphavirus core protein rve_3 PF13683.1 EMR66371.1 - 0.13 11.7 2.7 11 5.6 0.2 2.8 3 0 0 3 3 3 0 Integrase core domain FAM176 PF14851.1 EMR66371.1 - 0.23 11.1 5.6 0.072 12.7 1.5 1.9 2 0 0 2 2 2 0 FAM176 family SR-25 PF10500.4 EMR66371.1 - 0.47 9.8 34.5 0.016 14.6 13.1 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2231 PF09990.4 EMR66372.1 - 0.0033 17.7 0.1 0.0056 16.9 0.1 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) MARVEL PF01284.18 EMR66372.1 - 0.018 14.8 0.4 0.045 13.5 0.0 1.7 1 1 1 2 2 2 0 Membrane-associating domain Peptidase_M24 PF00557.19 EMR66373.1 - 9.4e-49 165.8 0.0 2.7e-48 164.3 0.0 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.11 EMR66373.1 - 3.2e-33 113.9 0.0 6.3e-33 113.0 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain COesterase PF00135.23 EMR66374.1 - 1.2e-71 242.0 1.2 1.8e-46 158.9 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR66374.1 - 0.00084 18.9 0.0 0.0021 17.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMR66374.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Dfp1_Him1_M PF08630.5 EMR66375.1 - 2.2e-44 150.2 0.0 6.8e-44 148.6 0.0 1.9 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EMR66375.1 - 4.2e-06 26.3 1.9 1e-05 25.0 1.3 1.7 1 0 0 1 1 1 1 DBF zinc finger Kringle PF00051.13 EMR66375.1 - 5.3 7.2 7.1 11 6.1 1.2 2.5 2 0 0 2 2 2 0 Kringle domain Sugar_tr PF00083.19 EMR66377.1 - 5.3e-45 153.8 31.3 3.1e-32 111.7 12.4 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 EMR66377.1 - 5.8e-25 87.7 47.2 1.2e-17 63.7 13.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Rad51 PF08423.6 EMR66378.1 - 3.2e-135 448.9 0.0 4.1e-135 448.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EMR66378.1 - 4.1e-13 49.1 0.0 5.9e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EMR66378.1 - 3.7e-07 29.5 0.0 4.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 EMR66378.1 - 1.7e-06 28.0 0.7 4e-06 26.9 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain KaiC PF06745.8 EMR66378.1 - 1.3e-05 24.4 0.0 2.5e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 KaiC PAXNEB PF05625.6 EMR66378.1 - 0.027 13.2 0.1 0.062 12.1 0.0 1.5 2 0 0 2 2 2 0 PAXNEB protein DnaB_C PF03796.10 EMR66378.1 - 0.048 12.5 0.0 0.086 11.7 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Aha1_N PF09229.6 EMR66379.1 - 7.4e-35 119.7 0.1 1.2e-34 119.1 0.1 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EMR66379.1 - 1.6e-18 67.0 0.6 1.6e-18 67.0 0.4 1.8 2 1 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein DUF2454 PF10521.4 EMR66379.1 - 0.15 11.0 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) Tannase PF07519.6 EMR66380.1 - 3.3e-60 204.1 0.0 1e-34 120.1 0.0 3.0 1 1 2 3 3 3 3 Tannase and feruloyl esterase Nuc_sug_transp PF04142.10 EMR66381.1 - 1.4e-77 260.1 3.8 2e-77 259.6 2.6 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EMR66381.1 - 2e-07 30.7 19.5 6.7e-05 22.5 0.8 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EMR66381.1 - 5.3e-07 28.8 10.7 2.2e-06 26.8 7.1 1.9 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EMR66381.1 - 1.3e-06 28.5 12.2 0.00012 22.2 0.5 2.4 2 0 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 EMR66381.1 - 2.2e-05 24.4 25.0 0.00066 19.7 3.7 2.7 2 1 0 2 2 2 2 EamA-like transporter family cobW PF02492.14 EMR66382.1 - 1e-46 158.6 2.5 2.7e-33 114.8 0.3 2.2 1 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EMR66382.1 - 2.2e-19 68.9 0.4 3.6e-14 52.2 0.1 2.7 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain ArgK PF03308.11 EMR66382.1 - 0.0013 17.5 0.3 1.1 7.9 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_16 PF13191.1 EMR66382.1 - 0.019 14.9 0.7 0.069 13.1 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EMR66382.1 - 0.024 14.1 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EMR66382.1 - 0.038 14.2 1.5 0.21 11.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EMR66382.1 - 0.044 13.4 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CDC45 PF02724.9 EMR66382.1 - 0.045 11.7 0.5 0.077 11.0 0.3 1.3 1 0 0 1 1 1 0 CDC45-like protein T2SE PF00437.15 EMR66382.1 - 0.062 12.1 0.6 0.098 11.5 0.4 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 EMR66382.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 EMR66382.1 - 0.091 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EMR66382.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Nop53 PF07767.6 EMR66382.1 - 0.55 9.1 6.4 1.1 8.1 4.4 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.7 EMR66382.1 - 1.2 6.9 7.9 2.1 6.1 5.4 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 EMR66382.1 - 6.9 6.2 11.0 1.8 8.1 4.2 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF1754 PF08555.5 EMR66383.1 - 0.041 14.4 4.9 0.06 13.9 0.3 2.1 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Nop14 PF04147.7 EMR66383.1 - 0.41 8.5 9.9 0.48 8.2 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF605 PF04652.11 EMR66383.1 - 0.54 9.6 6.0 0.62 9.3 4.2 1.1 1 0 0 1 1 1 0 Vta1 like CDC45 PF02724.9 EMR66383.1 - 2.9 5.7 6.7 3.5 5.5 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EMR66383.1 - 7 5.8 13.6 8.7 5.5 9.4 1.1 1 0 0 1 1 1 0 SDA1 DEAD PF00270.24 EMR66384.1 - 1.7e-29 102.4 0.0 3.6e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.11 EMR66384.1 - 2.1e-26 92.8 0.0 3.9e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.26 EMR66384.1 - 1.6e-09 37.5 0.0 3.8e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR66384.1 - 1.9e-09 37.6 0.0 4.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMR66384.1 - 0.0011 19.1 0.0 0.0041 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.9 EMR66384.1 - 0.008 15.8 0.0 0.035 13.7 0.0 2.1 2 0 0 2 2 2 1 Helicase SNF2_N PF00176.18 EMR66384.1 - 0.022 13.5 0.1 0.043 12.6 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain UvrD-helicase PF00580.16 EMR66384.1 - 0.039 13.2 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 EMR66384.1 - 0.043 13.5 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 EMR66384.1 - 0.2 11.9 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EMR66384.1 - 0.22 10.3 0.0 0.55 9.0 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein SLA_LP_auto_ag PF05889.8 EMR66384.1 - 0.24 9.8 0.0 0.41 9.0 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Abhydrolase_3 PF07859.8 EMR66387.1 - 9e-45 152.8 0.1 1.2e-44 152.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMR66387.1 - 3.7e-06 25.9 0.0 6.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family DLH PF01738.13 EMR66387.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EMR66387.1 - 0.079 12.1 0.0 3.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Vps26 PF03643.10 EMR66388.1 - 3.7e-102 340.7 0.9 5e-102 340.3 0.6 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 MMR_HSR1 PF01926.18 EMR66388.1 - 5.7e-17 61.7 0.0 1.4e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMR66388.1 - 2.3e-06 27.1 0.0 1.9e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMR66388.1 - 7.8e-05 21.9 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 EMR66388.1 - 0.0044 16.9 0.6 1.3 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EMR66388.1 - 0.062 14.1 0.5 1.4 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EMR66388.1 - 0.079 12.2 0.0 0.45 9.7 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.18 EMR66388.1 - 0.17 11.6 2.4 0.41 10.4 0.0 2.8 3 0 0 3 3 3 0 Dynamin family MFS_1 PF07690.11 EMR66389.1 - 1.4e-13 50.3 32.0 5.4e-08 31.9 11.4 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR66389.1 - 9.4e-08 31.0 13.4 2.8e-06 26.1 2.1 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter YL1_C PF08265.6 EMR66389.1 - 0.13 11.8 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain p450 PF00067.17 EMR66390.1 - 4.4e-35 121.0 0.0 5.2e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_2_C PF02836.12 EMR66391.1 - 1.3e-98 329.5 0.0 2e-98 328.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 EMR66391.1 - 4.3e-51 172.7 0.3 1.6e-50 170.9 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Bgal_small_N PF02929.12 EMR66391.1 - 4.7e-48 163.5 0.1 8.3e-48 162.7 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2 PF00703.16 EMR66391.1 - 2.3e-11 44.0 1.0 5.4e-10 39.6 0.0 2.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 bZIP_2 PF07716.10 EMR66391.1 - 3.3 7.6 6.2 0.71 9.7 1.2 2.0 2 0 0 2 2 2 0 Basic region leucine zipper MFS_1 PF07690.11 EMR66392.1 - 3.7e-16 58.7 19.8 3.7e-16 58.7 13.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EMR66392.1 - 1.6e-05 23.4 8.4 6.6e-05 21.4 1.7 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein DUF4131 PF13567.1 EMR66392.1 - 0.14 11.5 9.5 0.089 12.2 0.2 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) CopD PF05425.8 EMR66392.1 - 0.94 9.7 0.0 0.94 9.7 0.0 3.5 3 1 0 3 3 3 0 Copper resistance protein D TPP_enzyme_N PF02776.13 EMR66393.1 - 1e-35 122.7 0.2 1.7e-35 122.0 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMR66393.1 - 3.7e-18 65.6 0.0 9e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EMR66393.1 - 1.4e-16 60.4 0.1 8.8e-15 54.5 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Amidase PF01425.16 EMR66394.1 - 1.6e-93 313.9 0.0 1e-92 311.2 0.0 1.8 1 1 0 1 1 1 1 Amidase FAD_binding_3 PF01494.14 EMR66395.1 - 3.8e-71 239.9 0.0 5.4e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EMR66395.1 - 6.6e-34 116.9 0.0 1.2e-33 116.0 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.1 EMR66395.1 - 1.5e-05 24.9 0.0 3.8e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMR66395.1 - 2e-05 23.8 0.0 3.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EMR66395.1 - 7.9e-05 21.7 0.1 0.00013 20.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR66395.1 - 0.00012 22.0 0.0 0.00032 20.6 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR66395.1 - 0.00038 19.4 0.2 0.00066 18.6 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EMR66395.1 - 0.0014 17.6 0.3 0.0029 16.5 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EMR66395.1 - 0.0019 18.3 0.1 0.0077 16.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR66395.1 - 0.0027 16.2 0.0 0.0041 15.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EMR66395.1 - 0.0085 16.4 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.1 EMR66395.1 - 0.0091 16.3 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain Trp_halogenase PF04820.9 EMR66395.1 - 0.013 14.1 0.1 0.022 13.3 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 EMR66395.1 - 0.022 13.6 0.1 0.041 12.7 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EMR66395.1 - 0.029 13.4 0.4 0.053 12.5 0.1 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EMR66395.1 - 0.046 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EMR66395.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMR66395.1 - 0.06 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.1 EMR66395.1 - 0.072 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMR66395.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_4 PF01565.18 EMR66396.1 - 4.6e-28 97.4 0.3 9.2e-28 96.4 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain PD40 PF07676.7 EMR66397.1 - 1.5e-09 37.2 1.9 0.0014 18.2 0.0 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ring_hydroxyl_A PF00848.14 EMR66398.1 - 4.2e-33 114.7 1.7 4.2e-33 114.7 1.2 1.8 2 0 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EMR66398.1 - 2.5e-13 49.3 0.0 5.4e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAD_binding_3 PF01494.14 EMR66399.1 - 1.1e-17 64.1 0.1 7.6e-12 44.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR66399.1 - 2.8e-10 39.6 3.1 0.00033 19.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMR66399.1 - 4.9e-07 28.7 3.9 0.002 16.8 0.6 2.1 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EMR66399.1 - 1.6e-06 28.0 1.9 7.6e-05 22.6 1.3 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EMR66399.1 - 0.0011 17.5 3.7 0.041 12.3 2.9 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EMR66399.1 - 0.0012 19.1 1.0 0.043 14.2 0.7 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR66399.1 - 0.0015 17.5 1.5 0.0092 14.9 1.0 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMR66399.1 - 0.0022 18.0 0.2 0.0034 17.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR66399.1 - 0.0048 15.7 6.9 0.0048 15.7 4.8 2.0 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 EMR66399.1 - 0.0057 15.7 0.8 0.021 13.9 0.2 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EMR66399.1 - 0.0093 15.8 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMR66399.1 - 0.011 14.7 0.5 0.015 14.4 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EMR66399.1 - 0.041 13.4 0.8 0.19 11.2 0.3 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EMR66399.1 - 0.095 12.3 1.7 0.16 11.6 1.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EMR66399.1 - 0.9 8.3 7.7 0.56 9.0 4.2 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Oxidored_FMN PF00724.15 EMR66400.1 - 1.3e-80 271.0 0.0 5.4e-80 268.9 0.0 1.7 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.6 EMR66400.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Fungal_trans PF04082.13 EMR66402.1 - 1.8e-38 131.9 0.0 3e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Polysacc_deac_1 PF01522.16 EMR66403.1 - 2.5e-21 75.5 0.0 4.9e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EMR66403.1 - 8.4e-05 22.0 0.2 0.003 17.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2334) adh_short_C2 PF13561.1 EMR66404.1 - 7.2e-22 78.3 0.0 8.5e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR66404.1 - 2.3e-19 69.9 3.9 2.8e-19 69.6 2.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR66404.1 - 5.2e-09 36.0 1.0 1e-08 35.0 0.6 1.4 1 1 0 1 1 1 1 KR domain Glyco_transf_28 PF03033.15 EMR66404.1 - 0.0005 19.8 0.2 0.0089 15.7 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain MFS_1 PF07690.11 EMR66405.1 - 2.8e-34 118.3 29.4 2.8e-34 118.3 20.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF308 PF03729.8 EMR66405.1 - 1.3 9.0 25.1 0.22 11.5 6.2 3.9 2 1 2 4 4 4 0 Short repeat of unknown function (DUF308) DIOX_N PF14226.1 EMR66406.1 - 2.2e-29 102.3 0.0 3.3e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMR66406.1 - 6.6e-23 80.8 0.0 1.3e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aldedh PF00171.17 EMR66407.1 - 4.3e-119 397.8 0.0 5.1e-119 397.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMR66407.1 - 0.027 13.1 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF3359 PF11839.3 EMR66407.1 - 0.19 12.0 1.3 0.22 11.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) DIOX_N PF14226.1 EMR66408.1 - 1.2e-16 61.2 0.0 2.4e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMR66408.1 - 1.9e-13 50.5 0.0 3.2e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily THUMP PF02926.12 EMR66408.1 - 0.036 13.9 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 THUMP domain MFS_1 PF07690.11 EMR66409.1 - 1.5e-11 43.5 35.9 1.5e-06 27.2 16.1 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Abhydrolase_1 PF00561.15 EMR66410.1 - 3.3e-17 62.8 0.0 4.5e-16 59.0 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR66410.1 - 3e-10 40.3 3.6 1.7e-09 37.9 2.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EMR66410.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Aldo_ket_red PF00248.16 EMR66411.1 - 2.3e-53 180.8 0.0 3.4e-53 180.3 0.0 1.2 1 1 0 1 1 1 1 Aldo/keto reductase family Med21 PF11221.3 EMR66412.1 - 4.4e-46 156.4 7.5 4.9e-46 156.2 5.2 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Cast PF10174.4 EMR66412.1 - 0.0028 15.8 4.9 0.0044 15.1 3.4 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Med9 PF07544.8 EMR66412.1 - 0.0067 16.1 11.8 0.0074 15.9 0.9 3.1 2 2 1 3 3 3 2 RNA polymerase II transcription mediator complex subunit 9 TMCO5 PF14992.1 EMR66412.1 - 0.012 14.8 5.2 0.014 14.5 3.6 1.2 1 0 0 1 1 1 0 TMCO5 family GAS PF13851.1 EMR66412.1 - 0.016 14.4 8.5 0.86 8.7 3.6 2.1 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cauli_AT PF03233.8 EMR66412.1 - 0.13 11.9 2.7 0.2 11.3 1.9 1.3 1 0 0 1 1 1 0 Aphid transmission protein Fib_alpha PF08702.5 EMR66412.1 - 0.44 10.6 4.8 1.1 9.3 3.1 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spore_III_AB PF09548.5 EMR66412.1 - 1.4 8.6 4.4 2.2 8.0 3.0 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) TMF_DNA_bd PF12329.3 EMR66412.1 - 2.4 8.0 12.5 0.62 9.9 5.9 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 EMR66412.1 - 2.5 7.0 9.5 3.3 6.6 6.6 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 EMR66412.1 - 4.7 6.8 10.7 1.8 8.1 4.5 2.0 1 1 1 2 2 2 0 Mnd1 family DUF515 PF04415.7 EMR66413.1 - 2.9 6.0 6.1 4 5.5 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DNA_pol_phi PF04931.8 EMR66413.1 - 3.9 5.1 5.1 4.8 4.8 3.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi Ank_2 PF12796.2 EMR66414.1 - 1.3e-61 204.9 10.3 1.4e-17 63.7 0.0 5.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EMR66414.1 - 1.1e-59 195.3 13.5 1.8e-07 30.5 0.1 9.5 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 EMR66414.1 - 2.6e-50 167.9 11.2 1.2e-09 38.4 0.7 8.1 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR66414.1 - 9.9e-45 146.0 5.0 0.00031 20.7 0.0 9.4 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.1 EMR66414.1 - 1.2e-42 142.8 10.6 1.1e-09 38.1 0.0 7.2 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ligase_CoA PF00549.14 EMR66414.1 - 0.011 15.2 0.0 0.032 13.8 0.0 1.7 2 0 0 2 2 2 0 CoA-ligase HAD_2 PF13419.1 EMR66415.1 - 3.8e-27 95.6 0.1 4.7e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR66415.1 - 2.1e-06 28.2 0.0 4.7e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR66415.1 - 0.062 13.0 0.1 0.26 11.0 0.0 2.0 1 1 0 1 1 1 0 HAD-hyrolase-like CorA PF01544.13 EMR66416.1 - 2.2e-07 30.2 5.3 2.2e-07 30.2 3.7 2.8 2 2 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.4 EMR66416.1 - 0.0084 14.7 0.1 0.012 14.2 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF605 PF04652.11 EMR66417.1 - 0.36 10.1 11.1 0.36 10.1 7.7 1.1 1 0 0 1 1 1 0 Vta1 like KH_1 PF00013.24 EMR66418.1 - 8.4e-29 99.0 2.9 1.1e-07 31.4 0.2 7.3 7 0 0 7 7 7 6 KH domain KH_3 PF13014.1 EMR66418.1 - 1.3e-27 94.9 4.7 1.6e-06 27.5 0.0 6.8 7 0 0 7 7 7 5 KH domain TGT PF01702.13 EMR66420.1 - 5.4e-72 241.9 0.0 2.9e-70 236.2 0.0 2.0 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase GFA PF04828.9 EMR66421.1 - 0.0036 17.2 1.2 0.0036 17.2 0.8 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme YihI PF04220.7 EMR66422.1 - 6.6 6.0 6.1 2.3 7.5 1.7 1.8 2 0 0 2 2 2 0 Der GTPase activator (YihI) Sugar_tr PF00083.19 EMR66423.1 - 1e-91 307.8 29.9 1.2e-91 307.5 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR66423.1 - 3.7e-19 68.6 29.1 3.7e-19 68.6 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_11 PF08241.7 EMR66424.1 - 3.9e-13 49.6 0.0 9.2e-13 48.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR66424.1 - 7.6e-10 39.3 0.0 1.4e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR66424.1 - 2.2e-09 37.7 0.0 3.9e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR66424.1 - 3.9e-07 29.7 0.0 1e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR66424.1 - 4.7e-07 29.6 0.0 7.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR66424.1 - 1e-06 28.7 0.1 5.6e-06 26.3 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR66424.1 - 1.1e-06 28.9 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR66424.1 - 0.0021 17.2 0.0 0.0044 16.1 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EMR66424.1 - 0.11 11.5 0.0 0.32 10.0 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase 2OG-FeII_Oxy_2 PF13532.1 EMR66425.1 - 6.6e-29 101.1 0.0 9.9e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 EMR66425.1 - 5.1e-10 39.1 3.6 9e-10 38.3 2.5 1.4 1 0 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 EMR66425.1 - 0.0073 16.5 0.0 0.019 15.2 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NAD_binding_4 PF07993.7 EMR66427.1 - 4.9e-32 110.8 0.0 7.3e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EMR66427.1 - 1.3e-15 56.7 0.0 5.3e-14 51.4 0.0 2.7 2 1 1 3 3 3 1 AMP-binding enzyme Epimerase PF01370.16 EMR66427.1 - 1.3e-10 41.1 0.0 2.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMR66427.1 - 1.2e-05 25.4 0.0 3.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EMR66427.1 - 0.00024 20.0 0.0 0.016 14.1 0.0 2.6 2 1 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 EMR66427.1 - 0.00028 20.8 0.1 0.0014 18.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 EMR66427.1 - 0.041 14.1 0.0 0.26 11.6 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EMR66427.1 - 0.044 13.4 1.0 0.093 12.3 0.0 2.0 2 0 0 2 2 2 0 KR domain Isochorismatase PF00857.15 EMR66429.1 - 8.4e-36 123.5 0.0 9.5e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family NAD_binding_2 PF03446.10 EMR66430.1 - 1.1e-35 122.8 0.0 2.5e-35 121.6 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMR66430.1 - 2.5e-14 53.3 1.5 3.6e-14 52.8 1.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EMR66430.1 - 4.6e-05 23.7 0.0 0.00042 20.6 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EMR66430.1 - 0.03 13.4 0.0 0.16 11.1 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMR66430.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EMR66430.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EMR66430.1 - 0.12 11.9 0.0 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Aldo_ket_red PF00248.16 EMR66431.1 - 8.2e-67 224.9 0.2 9.3e-67 224.8 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PHA_synth_III_E PF09712.5 EMR66431.1 - 0.037 13.4 0.4 0.076 12.4 0.3 1.4 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) FAD_binding_3 PF01494.14 EMR66432.1 - 5.9e-26 91.3 0.1 7.7e-15 54.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR66432.1 - 3.3e-07 29.5 0.8 0.0011 17.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR66432.1 - 2e-05 24.7 0.0 5.7e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR66432.1 - 3.4e-05 24.1 0.2 0.0014 19.0 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR66432.1 - 7.7e-05 22.6 0.5 0.0003 20.7 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMR66432.1 - 0.0075 15.3 0.1 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EMR66432.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EMR66432.1 - 0.04 13.3 0.1 0.074 12.4 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF2204 PF09970.4 EMR66432.1 - 0.044 13.2 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) UDPG_MGDP_dh_N PF03721.9 EMR66432.1 - 0.094 12.0 0.2 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Myb_DNA-bind_3 PF12776.2 EMR66433.1 - 1.7e-17 63.8 0.3 3.2e-17 62.9 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RFX5_DNA_bdg PF14621.1 EMR66433.1 - 0.42 10.1 3.7 0.69 9.4 2.6 1.3 1 0 0 1 1 1 0 RFX5 DNA-binding domain RAP1 PF07218.6 EMR66433.1 - 1.7 6.6 4.1 2.1 6.3 2.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cutinase PF01083.17 EMR66435.1 - 6.3e-49 166.1 10.6 7.2e-49 165.9 7.3 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EMR66435.1 - 6.7e-06 25.6 0.1 9.4e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 EMR66435.1 - 0.002 17.7 0.1 0.011 15.2 0.0 2.1 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR66435.1 - 0.068 13.0 0.3 0.12 12.2 0.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 EMR66435.1 - 0.12 11.9 0.8 1.5 8.4 0.0 2.7 4 0 0 4 4 4 0 Lipase (class 3) Sec63 PF02889.11 EMR66436.1 - 7.3e-154 511.6 0.0 9.8e-98 327.2 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EMR66436.1 - 3.1e-51 173.2 0.4 2.2e-27 95.6 0.4 3.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR66436.1 - 1.3e-16 60.1 0.0 6.6e-07 29.1 0.0 3.4 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EMR66436.1 - 2e-14 53.8 0.2 1.2e-05 25.2 0.0 2.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMR66436.1 - 1.8e-07 31.3 0.1 0.06 13.4 0.1 4.0 3 2 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EMR66436.1 - 4.8e-05 23.0 1.5 0.017 14.8 0.0 3.2 3 0 0 3 3 3 1 Part of AAA domain SNF2_N PF00176.18 EMR66436.1 - 0.00071 18.4 0.3 0.78 8.4 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain IstB_IS21 PF01695.12 EMR66436.1 - 0.0072 15.7 0.3 8.7 5.7 0.0 3.9 4 0 0 4 4 4 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EMR66436.1 - 0.009 15.5 0.0 0.91 8.9 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF3365 PF11845.3 EMR66436.1 - 0.024 14.5 0.4 0.089 12.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) AAA_10 PF12846.2 EMR66436.1 - 0.06 12.7 0.0 30 3.8 0.0 3.7 4 0 0 4 4 4 0 AAA-like domain Phage_XkdX PF09693.5 EMR66437.1 - 0.089 12.3 0.2 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) TPR_MLP1_2 PF07926.7 EMR66438.1 - 6.9e-27 93.7 21.6 6.9e-27 93.7 15.0 18.5 6 3 11 17 17 17 2 TPR/MLP1/MLP2-like protein IncA PF04156.9 EMR66438.1 - 0.00024 20.7 13.9 0.00024 20.7 9.6 15.9 2 1 9 13 13 13 1 IncA protein CENP-F_leu_zip PF10473.4 EMR66438.1 - 0.006 16.4 0.9 0.006 16.4 0.6 18.5 8 5 11 19 19 19 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fungal_trans PF04082.13 EMR66439.1 - 0.00044 19.2 0.0 0.00063 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SKG6 PF08693.5 EMR66440.1 - 4e-05 22.8 0.4 8.4e-05 21.8 0.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 EMR66440.1 - 0.007 15.2 0.0 0.015 14.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Squash PF00299.13 EMR66440.1 - 0.21 11.4 3.5 6.2 6.7 0.3 2.4 2 0 0 2 2 2 0 Squash family serine protease inhibitor Rick_17kDa_Anti PF05433.10 EMR66443.1 - 0.041 13.5 4.6 0.1 12.3 3.2 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain Ilar_coat PF01787.11 EMR66443.1 - 0.059 12.9 1.8 0.099 12.2 1.2 1.2 1 0 0 1 1 1 0 Ilarvirus coat protein DUF2456 PF10445.4 EMR66444.1 - 2.3e-17 62.6 1.4 2.3e-17 62.6 1.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) MMR_HSR1 PF01926.18 EMR66445.1 - 7.4e-06 25.9 0.0 6e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF3712 PF12505.3 EMR66446.1 - 7.5e-10 38.9 0.2 2.2e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF3310 PF11753.3 EMR66446.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknwon function (DUF3310) L51_S25_CI-B8 PF05047.11 EMR66447.1 - 3.3e-22 77.9 0.0 6e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Arylsulfotran_2 PF14269.1 EMR66448.1 - 9.2e-47 159.6 0.0 1.3e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EMR66448.1 - 6.1e-19 67.8 0.0 2.4e-18 65.8 0.0 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) adh_short PF00106.20 EMR66449.1 - 4.3e-12 46.2 3.7 2.2e-11 43.9 2.6 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR66449.1 - 6.6e-07 29.1 0.4 1.2e-06 28.3 0.3 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMR66449.1 - 0.0059 15.5 0.0 0.0083 15.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF3383 PF11863.3 EMR66449.1 - 0.033 12.8 0.3 0.043 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) PPI_Ypi1 PF07491.6 EMR66451.1 - 3.8e-24 84.0 6.0 4.7e-23 80.5 4.1 2.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor MFS_1 PF07690.11 EMR66452.1 - 0.026 13.2 14.4 0.075 11.7 10.0 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR66452.1 - 0.17 10.4 6.1 0.29 9.6 4.0 1.6 1 1 0 1 1 1 0 Sugar (and other) transporter Cobl PF09469.5 EMR66453.1 - 0.0089 15.9 0.3 1.1 9.2 0.0 2.3 2 0 0 2 2 2 2 Cordon-bleu ubiquitin-like domain Rbsn PF11464.3 EMR66453.1 - 0.016 14.7 0.1 0.039 13.5 0.1 1.6 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Peptidase_S8 PF00082.17 EMR66455.1 - 1.4e-12 47.3 0.5 1.4e-12 47.3 0.4 1.9 2 1 0 2 2 2 1 Subtilase family Ank_2 PF12796.2 EMR66455.1 - 2.8e-07 30.7 5.4 0.00022 21.5 0.3 3.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMR66455.1 - 0.00084 19.0 0.1 3.8 7.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMR66455.1 - 0.0013 18.8 0.1 0.18 12.1 0.0 3.6 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR66455.1 - 0.0028 18.1 0.0 11 6.6 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR66455.1 - 0.085 13.1 2.2 12 6.5 0.0 4.4 4 0 0 4 4 4 0 Ankyrin repeat MT0933_antitox PF14013.1 EMR66455.1 - 0.11 12.6 0.2 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 MT0933-like antitoxin protein Serglycin PF04360.7 EMR66456.1 - 0.28 10.9 1.9 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 Serglycin DUF1680 PF07944.7 EMR66457.1 - 2.1e-131 438.7 2.6 2.4e-131 438.5 1.8 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) GMC_oxred_C PF05199.8 EMR66458.1 - 8.9e-35 120.0 0.1 3.1e-34 118.3 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR66458.1 - 3.8e-27 95.2 0.0 5.3e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 EMR66458.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IMS PF00817.15 EMR66459.1 - 1.9e-32 112.1 0.0 8.2e-32 110.0 0.0 2.0 1 1 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.3 EMR66459.1 - 0.0052 16.7 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif GET2 PF08690.5 EMR66460.1 - 2.5e-13 49.9 0.0 1.1e-07 31.3 0.0 3.1 3 0 0 3 3 3 3 GET complex subunit GET2 WD40 PF00400.27 EMR66461.1 - 3.7e-14 51.9 18.1 0.00052 19.7 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EMR66461.1 - 0.00051 18.3 1.3 0.17 9.9 0.0 2.9 2 1 0 3 3 3 2 Nucleoporin Nup120/160 DUF627 PF04781.7 EMR66461.1 - 0.007 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF627) HLH PF00010.21 EMR66462.1 - 3.1e-09 36.3 3.3 1.6e-08 34.1 0.0 3.4 4 0 0 4 4 4 1 Helix-loop-helix DNA-binding domain DNA_pol3_a_NII PF11490.3 EMR66462.1 - 6.4 6.4 11.7 38 3.9 3.2 3.2 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus II DUF4091 PF13320.1 EMR66463.1 - 0.12 12.2 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) WD40 PF00400.27 EMR66465.1 - 4.5e-27 92.9 7.1 1.5e-09 37.3 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF3639 PF12341.3 EMR66465.1 - 6.1e-09 35.7 1.4 2e-08 34.0 0.9 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 EMR66465.1 - 5.6e-08 32.0 0.0 1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.6 EMR66465.1 - 3.6e-05 23.5 0.0 0.00056 19.6 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EMR66465.1 - 0.0027 15.6 0.0 0.0084 13.9 0.0 1.7 2 0 0 2 2 2 1 IKI3 family DNA_pol_alpha_N PF12254.3 EMR66465.1 - 0.0031 17.3 0.9 0.012 15.4 0.6 2.0 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DUF3312 PF11768.3 EMR66465.1 - 0.14 10.3 0.0 3.9 5.5 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3312) PBP1_TM PF14812.1 EMR66465.1 - 6.4 7.1 12.3 1 9.7 3.5 2.6 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal dDENN PF03455.14 EMR66466.1 - 1.1e-16 60.5 0.3 1.8e-16 59.9 0.2 1.2 1 0 0 1 1 1 1 dDENN domain C1_1 PF00130.17 EMR66466.1 - 0.032 13.9 8.7 0.055 13.2 6.0 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 EMR66466.1 - 0.28 11.0 7.0 0.57 10.0 4.9 1.6 1 0 0 1 1 1 0 Ring finger domain C1_3 PF07649.7 EMR66466.1 - 0.77 9.8 5.9 1.4 9.0 4.1 1.4 1 0 0 1 1 1 0 C1-like domain PHD PF00628.24 EMR66466.1 - 1.1 9.0 9.8 2.1 8.0 6.8 1.5 1 0 0 1 1 1 0 PHD-finger OrfB_Zn_ribbon PF07282.6 EMR66466.1 - 1.4 8.6 8.0 2.5 7.8 5.5 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF974 PF06159.8 EMR66467.1 - 6.9e-80 268.0 0.0 8.2e-80 267.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Transp_cyt_pur PF02133.10 EMR66468.1 - 5.4e-89 298.7 39.3 7e-89 298.3 27.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ank_2 PF12796.2 EMR66469.1 - 1.2e-212 688.9 47.4 7.6e-20 71.0 0.0 16.8 3 3 17 20 20 20 20 Ankyrin repeats (3 copies) Ank PF00023.25 EMR66469.1 - 1.9e-140 450.2 42.6 2.7e-07 30.0 0.1 30.2 31 0 0 31 31 31 26 Ankyrin repeat Ank_4 PF13637.1 EMR66469.1 - 1.2e-107 350.6 18.6 5.5e-09 36.2 0.1 21.7 9 6 13 23 23 23 22 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR66469.1 - 4.4e-95 309.5 37.5 8.4e-09 35.3 0.0 25.2 11 6 16 27 27 27 24 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR66469.1 - 4.5e-86 274.0 18.4 3.8e-05 23.5 0.0 29.1 32 0 0 32 32 32 19 Ankyrin repeat SPRY PF00622.23 EMR66469.1 - 1e-15 57.9 0.3 2.2e-15 56.8 0.2 1.6 1 0 0 1 1 1 1 SPRY domain Acetyltransf_1 PF00583.19 EMR66470.1 - 0.0089 16.0 0.0 0.026 14.5 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR66470.1 - 0.058 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidase PF01425.16 EMR66471.1 - 3.5e-88 296.3 0.0 4e-88 296.1 0.0 1.0 1 0 0 1 1 1 1 Amidase HECT PF00632.20 EMR66472.1 - 1.1e-73 248.1 0.0 9.9e-73 245.0 0.0 2.0 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF998 PF06197.8 EMR66473.1 - 0.002 17.4 9.0 0.24 10.6 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF998) Con-6 PF10346.4 EMR66474.1 - 2.4e-07 30.0 0.4 4.2e-07 29.2 0.3 1.5 1 0 0 1 1 1 1 Conidiation protein 6 DUF4145 PF13643.1 EMR66474.1 - 0.049 13.4 0.2 0.069 13.0 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4145) TauD PF02668.11 EMR66476.1 - 3.5e-50 171.0 0.7 5.1e-50 170.5 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family C2 PF00168.25 EMR66477.1 - 3.6e-21 74.7 0.0 1.3e-14 53.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain Vfa1 PF08432.5 EMR66478.1 - 0.6 10.1 3.8 0.6 10.1 1.3 1.9 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 GFO_IDH_MocA PF01408.17 EMR66479.1 - 1.1e-16 61.3 0.0 2.6e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMR66479.1 - 0.00017 21.3 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PseudoU_synth_2 PF00849.17 EMR66480.1 - 4.4e-15 55.8 0.1 7.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Barwin PF00967.12 EMR66480.1 - 0.092 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Barwin family bZIP_1 PF00170.16 EMR66481.1 - 0.00025 20.9 14.5 0.00043 20.1 5.9 2.2 1 1 1 2 2 2 2 bZIP transcription factor ATG16 PF08614.6 EMR66481.1 - 0.089 12.6 9.1 0.14 11.9 6.3 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Mnd1 PF03962.10 EMR66481.1 - 0.29 10.7 3.4 0.4 10.3 2.3 1.2 1 0 0 1 1 1 0 Mnd1 family adh_short PF00106.20 EMR66482.1 - 1.2e-20 74.0 0.0 4.6e-19 68.9 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR66482.1 - 2.1e-08 34.0 0.0 3.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR66482.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EMR66482.1 - 0.0027 17.4 0.7 0.0075 16.0 0.3 1.8 1 1 1 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 EMR66482.1 - 0.02 15.1 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 EMR66482.1 - 0.024 14.6 0.2 0.046 13.7 0.2 1.5 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EMR66482.1 - 0.027 13.9 0.0 0.069 12.5 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Helicase_RecD PF05127.9 EMR66482.1 - 0.076 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Helicase Linker_histone PF00538.14 EMR66483.1 - 2e-22 79.0 0.2 2e-22 79.0 0.1 1.9 2 0 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.6 EMR66483.1 - 0.037 13.8 75.1 0.069 13.0 52.1 1.5 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Asp-B-Hydro_N PF05279.6 EMR66483.1 - 9.4 6.0 16.2 11 5.7 11.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Zip PF02535.17 EMR66484.1 - 0.9 8.4 5.4 0.25 10.3 0.8 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Sulfotransfer_3 PF13469.1 EMR66486.1 - 4.7e-06 27.6 0.7 1.4e-05 26.0 0.5 1.7 1 1 0 1 1 1 1 Sulfotransferase family DUF4234 PF14018.1 EMR66486.1 - 0.023 14.4 0.4 0.043 13.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) PsbN PF02468.10 EMR66486.1 - 0.17 11.5 3.3 0.34 10.5 2.3 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Zip PF02535.17 EMR66488.1 - 0.016 14.2 4.5 0.018 14.0 3.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.4 EMR66488.1 - 0.38 9.5 6.8 0.48 9.2 4.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.6 EMR66488.1 - 4.2 5.3 17.0 5.1 5.0 11.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 EMR66488.1 - 6.2 4.9 13.8 8.1 4.5 9.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Tmemb_cc2 PF10267.4 EMR66488.1 - 6.4 5.2 8.3 7.6 5.0 5.7 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Glyco_hydro_43 PF04616.9 EMR66489.1 - 2.6e-13 49.7 2.8 4.9e-13 48.8 1.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Coa1 PF08695.5 EMR66489.1 - 0.077 12.5 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Cytochrome oxidase complex assembly protein 1 DDE_1 PF03184.14 EMR66490.1 - 0.012 14.7 0.0 0.1 11.7 0.0 1.9 1 1 1 2 2 2 0 DDE superfamily endonuclease Sugar_tr PF00083.19 EMR66491.1 - 5.9e-63 212.9 18.5 6.9e-63 212.7 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR66491.1 - 1.1e-20 73.6 34.7 4.8e-20 71.5 10.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF554 PF04474.7 EMR66491.1 - 0.0059 15.7 6.9 0.0073 15.4 2.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF554) HET PF06985.6 EMR66492.1 - 0.0069 16.5 0.0 0.022 14.8 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Neugrin PF06413.6 EMR66493.1 - 1.2e-08 35.1 0.3 1.2e-08 35.1 0.2 2.8 2 1 1 3 3 3 1 Neugrin PPP4R2 PF09184.6 EMR66493.1 - 6.2 6.2 17.3 2.7 7.4 10.3 1.5 1 1 0 1 1 1 0 PPP4R2 RNA_pol_A_bac PF01000.21 EMR66494.1 - 6.5e-31 106.7 0.0 1.1e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EMR66494.1 - 5.8e-12 44.5 0.0 1.3e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain His_Phos_2 PF00328.17 EMR66494.1 - 3.7e-08 33.0 0.0 1.1e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Proteasome PF00227.21 EMR66495.1 - 8.2e-53 178.5 0.0 6.9e-29 100.4 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EMR66495.1 - 1.9e-11 43.0 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Mito_carr PF00153.22 EMR66496.1 - 6.3e-52 173.2 0.5 1.2e-21 76.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Calcipressin PF04847.7 EMR66497.1 - 1.2e-52 178.2 0.0 1.5e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Calcipressin Pyr_redox_3 PF13738.1 EMR66498.1 - 1.8e-24 86.9 0.0 5e-24 85.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR66498.1 - 3.3e-17 61.8 0.0 3.2e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMR66498.1 - 1.8e-11 43.8 0.0 3.4e-10 39.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Fringe PF02434.11 EMR66498.1 - 1.4e-09 37.5 0.0 2.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Fringe-like DAO PF01266.19 EMR66498.1 - 3.8e-08 32.6 0.0 0.00011 21.2 0.0 3.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EMR66498.1 - 2e-06 27.0 2.4 7.3e-05 21.8 0.0 3.2 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EMR66498.1 - 7.4e-05 21.9 0.1 0.0016 17.6 0.0 2.5 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.22 EMR66498.1 - 0.00014 22.1 0.1 0.43 11.0 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR66498.1 - 0.00028 20.7 1.7 0.26 11.0 0.0 4.3 3 1 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMR66498.1 - 0.00043 20.2 0.0 1.2 8.9 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR66498.1 - 0.0017 17.3 0.1 0.24 10.2 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein PAN_4 PF14295.1 EMR66498.1 - 0.044 13.4 4.9 0.18 11.5 3.4 2.0 1 1 0 1 1 1 0 PAN domain NAD_binding_7 PF13241.1 EMR66498.1 - 0.16 12.2 0.0 0.53 10.5 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 EMR66498.1 - 0.23 10.8 0.5 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EMR66498.1 - 0.24 11.1 0.3 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Mei4 PF13971.1 EMR66498.1 - 0.25 10.2 0.0 0.43 9.4 0.0 1.3 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 Shikimate_DH PF01488.15 EMR66498.1 - 0.26 11.3 0.1 7.6 6.6 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Ribonuclease_3 PF00636.21 EMR66499.1 - 3.6e-37 127.2 0.0 3e-22 79.2 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EMR66499.1 - 1e-27 96.6 0.0 1.3e-15 57.4 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.24 EMR66499.1 - 1e-18 67.4 0.0 2.9e-18 65.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR66499.1 - 9.1e-18 63.9 0.0 2.3e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 EMR66499.1 - 6.7e-14 51.4 0.0 1.4e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.10 EMR66499.1 - 6.1e-12 45.7 0.0 2.3e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMR66499.1 - 0.011 14.6 0.0 0.022 13.5 0.0 1.6 1 1 0 1 1 1 0 SNF2 family N-terminal domain Pec_lyase_C PF00544.14 EMR66500.1 - 5.6e-48 163.0 4.6 7.5e-48 162.6 3.2 1.1 1 0 0 1 1 1 1 Pectate lyase GrpE PF01025.14 EMR66502.1 - 5.2e-49 165.9 10.7 1.1e-48 164.9 7.4 1.5 1 1 0 1 1 1 1 GrpE PsbQ PF05757.6 EMR66502.1 - 0.042 13.2 2.9 0.06 12.7 2.0 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) tRNA-synt_2d PF01409.15 EMR66504.1 - 5.4e-48 163.3 0.1 1.5e-24 86.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EMR66504.1 - 3.6e-25 87.9 0.0 7.3e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain HATPase_c_2 PF13581.1 EMR66504.1 - 0.031 14.0 0.1 0.071 12.9 0.1 1.6 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain Gly-zipper_OmpA PF13436.1 EMR66506.1 - 0.0022 17.6 2.8 0.026 14.1 0.1 2.6 1 1 1 2 2 2 2 Glycine-zipper containing OmpA-like membrane domain DUF4235 PF14019.1 EMR66506.1 - 0.0066 16.2 1.1 0.042 13.6 0.8 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4235) AATF-Che1 PF13339.1 EMR66507.1 - 0.38 10.8 4.6 0.2 11.8 1.5 1.7 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor ADH_N PF08240.7 EMR66508.1 - 4.3e-08 32.8 0.1 1.1e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR66508.1 - 0.0033 16.9 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Inhibitor_I68 PF10468.4 EMR66509.1 - 0.11 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 Bacillus_HBL PF05791.6 EMR66509.1 - 0.25 10.6 9.2 4.7 6.5 3.6 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TMF_DNA_bd PF12329.3 EMR66509.1 - 5.9 6.7 23.0 1.9 8.3 6.1 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding 4F5 PF04419.9 EMR66511.1 - 5.9e-08 33.3 16.1 5.9e-08 33.3 11.2 2.4 1 1 1 2 2 2 1 4F5 protein family Ead_Ea22 PF13935.1 EMR66511.1 - 3.4 7.9 10.2 3.7 7.8 7.0 1.0 1 0 0 1 1 1 0 Ead/Ea22-like protein Selenoprotein_S PF06936.6 EMR66511.1 - 7.4 6.0 8.8 7.4 6.0 6.1 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) GRAB PF10375.4 EMR66512.1 - 2.4e-08 33.2 0.1 4.5e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain CENP-F_leu_zip PF10473.4 EMR66512.1 - 0.014 15.2 21.9 0.014 15.2 15.2 3.8 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tup_N PF08581.5 EMR66512.1 - 0.014 15.5 2.6 0.014 15.5 1.8 4.2 3 1 1 4 4 4 0 Tup N-terminal Reo_sigmaC PF04582.7 EMR66512.1 - 0.016 14.3 10.7 0.12 11.5 2.6 2.9 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Bacillus_HBL PF05791.6 EMR66512.1 - 0.054 12.8 21.3 0.14 11.5 2.2 3.5 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Filament PF00038.16 EMR66512.1 - 0.058 12.8 57.0 0.36 10.2 26.2 2.5 1 1 0 2 2 2 0 Intermediate filament protein Spc7 PF08317.6 EMR66512.1 - 0.098 11.3 46.7 0.16 10.5 12.2 3.4 1 1 2 3 3 3 0 Spc7 kinetochore protein AAA_27 PF13514.1 EMR66512.1 - 0.39 8.3 60.0 1.3 6.6 41.6 1.7 1 1 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 EMR66512.1 - 0.49 10.2 15.3 2.7 7.7 2.5 3.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 EMR66512.1 - 0.58 10.0 22.3 4.3 7.3 0.5 5.3 3 1 3 6 6 6 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 EMR66512.1 - 0.87 8.5 55.3 0.043 12.8 20.3 2.9 1 1 2 3 3 3 0 Autophagy protein Apg6 DUF1664 PF07889.7 EMR66512.1 - 1.1 9.1 21.1 0.19 11.4 1.7 4.0 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 EMR66512.1 - 1.2 9.2 24.8 3.7 7.6 7.5 3.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 EMR66512.1 - 1.3 9.3 15.6 1.9 8.8 0.9 4.3 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 EMR66512.1 - 8 3.6 61.0 1.7 5.8 32.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 EMR66512.1 - 9.6 5.9 69.3 0.057 13.1 15.2 5.1 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein Cu_bind_like PF02298.12 EMR66513.1 - 0.02 14.7 0.0 0.073 12.8 0.0 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain RRM_1 PF00076.17 EMR66514.1 - 9.5e-14 50.7 0.0 2.5e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR66514.1 - 9.9e-09 34.9 0.1 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR66514.1 - 2e-07 30.9 0.0 3.7e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1731 PF08338.6 EMR66514.1 - 0.037 13.5 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Nup35_RRM_2 PF14605.1 EMR66514.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Aa_trans PF01490.13 EMR66515.1 - 4e-61 206.7 24.8 1.1e-33 116.3 7.1 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein CHD5 PF04420.9 EMR66516.1 - 9.6e-59 197.6 1.1 1.2e-58 197.3 0.7 1.1 1 0 0 1 1 1 1 CHD5-like protein DUF4133 PF13571.1 EMR66518.1 - 0.16 12.1 1.1 0.29 11.3 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4133) Asp PF00026.18 EMR66519.1 - 2e-66 224.4 3.5 3.2e-66 223.7 2.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMR66519.1 - 1.4e-11 44.6 1.2 2.7e-11 43.6 0.2 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EMR66519.1 - 1.8e-05 24.3 0.1 0.00033 20.2 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EMR66519.1 - 0.00087 19.7 0.4 0.24 11.8 0.0 3.2 2 1 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EMR66519.1 - 0.036 13.9 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease zf-C2H2_4 PF13894.1 EMR66520.1 - 0.001 19.2 1.1 2.4 8.6 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EMR66520.1 - 0.0034 17.0 1.9 0.33 10.6 0.1 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type Zn_Tnp_IS91 PF14319.1 EMR66520.1 - 0.01 15.3 0.7 0.24 10.9 0.0 2.4 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-C2H2 PF00096.21 EMR66520.1 - 0.035 14.4 2.3 5.9 7.4 0.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMR66520.1 - 0.058 13.7 1.4 4.3 7.7 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double domain C1_1 PF00130.17 EMR66520.1 - 0.13 11.9 1.5 23 4.7 0.0 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EMR66520.1 - 0.44 10.3 4.9 6.2 6.6 0.0 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2H2_6 PF13912.1 EMR66520.1 - 1.8 8.6 5.9 4.7 7.2 0.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Bac_rhamnosid PF05592.6 EMR66521.1 - 1.3e-181 604.2 0.1 1.6e-181 604.0 0.1 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EMR66521.1 - 5.4e-61 205.0 0.2 1.1e-60 204.1 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain SFTA2 PF15210.1 EMR66521.1 - 0.18 11.4 0.0 0.45 10.1 0.0 1.6 1 0 0 1 1 1 0 Surfactant-associated protein 2 CopD PF05425.8 EMR66522.1 - 0.00062 19.9 2.7 0.0062 16.7 0.0 2.8 3 0 0 3 3 3 1 Copper resistance protein D DUF3382 PF11862.3 EMR66522.1 - 0.17 11.8 7.6 0.66 9.9 0.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) DUF161 PF02588.10 EMR66522.1 - 0.65 10.3 4.2 0.14 12.5 0.3 1.8 2 0 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 Glyoxalase_3 PF13468.1 EMR66523.1 - 0.00014 21.8 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain Cyclin_N PF00134.18 EMR66524.1 - 2.8e-38 130.3 0.8 3.7e-38 129.9 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMR66524.1 - 1.8e-12 47.2 1.5 6.1e-12 45.5 1.0 1.9 1 1 0 1 1 1 1 Cyclin, C-terminal domain DUF3526 PF12040.3 EMR66524.1 - 0.074 13.1 0.2 1.8 8.7 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3526) TFIIA PF03153.8 EMR66525.1 - 4e-81 273.7 1.5 6.7e-81 273.0 1.1 1.3 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ADH_N PF08240.7 EMR66528.1 - 1.2e-13 50.7 0.6 3.1e-13 49.4 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR66528.1 - 3.8e-10 39.4 0.4 3.7e-09 36.2 0.1 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMR66528.1 - 3.3e-05 23.1 0.0 5.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EMR66528.1 - 0.0036 16.8 0.0 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EMR66528.1 - 0.019 14.6 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EMR66528.1 - 0.023 14.5 0.0 0.048 13.5 0.0 1.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 EMR66528.1 - 0.21 11.3 0.7 0.37 10.5 0.5 1.3 1 0 0 1 1 1 0 ThiF family Aldo_ket_red PF00248.16 EMR66529.1 - 4.1e-54 183.3 0.0 4.6e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_S8 PF00082.17 EMR66531.1 - 2.3e-46 158.2 6.9 3.1e-46 157.7 4.8 1.1 1 0 0 1 1 1 1 Subtilase family Aminotran_3 PF00202.16 EMR66532.1 - 1e-90 304.0 0.0 1.2e-90 303.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Peptidase_M19 PF01244.16 EMR66533.1 - 1.7e-52 178.3 0.1 2e-52 178.1 0.1 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF3425 PF11905.3 EMR66534.1 - 1.6e-29 102.5 0.1 2.3e-29 102.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Zot PF05707.7 EMR66535.1 - 0.15 11.5 0.1 0.52 9.7 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) MFS_1 PF07690.11 EMR66536.1 - 6.9e-34 117.0 29.9 1.1e-33 116.4 19.0 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily IKI3 PF04762.7 EMR66537.1 - 1.7e-136 456.4 0.1 2e-136 456.1 0.1 1.0 1 0 0 1 1 1 1 IKI3 family WD40 PF00400.27 EMR66537.1 - 0.00034 20.3 3.1 16 5.5 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Hpt PF01627.18 EMR66538.1 - 6.8e-15 54.8 0.0 9.4e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 Hpt domain DUF3984 PF13136.1 EMR66539.1 - 7.7e-33 114.0 12.6 4.7e-24 85.2 2.7 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3984) F-box-like PF12937.2 EMR66540.1 - 3.8e-12 45.7 0.0 1.9e-11 43.4 0.0 2.3 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 EMR66540.1 - 6.1e-08 31.9 8.6 0.15 12.1 0.0 7.7 9 0 0 9 9 9 1 Leucine Rich repeat LRR_1 PF00560.28 EMR66540.1 - 9.7e-06 24.9 17.3 0.047 13.7 0.0 7.8 7 2 0 7 7 7 2 Leucine Rich Repeat F-box PF00646.28 EMR66540.1 - 6.9e-05 22.3 0.0 0.00022 20.7 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 EMR66540.1 - 9.4e-05 22.0 10.1 0.013 15.2 0.1 4.6 3 1 1 4 4 4 1 Leucine rich repeat LRR_4 PF12799.2 EMR66540.1 - 0.00013 21.5 18.7 0.016 14.8 0.0 6.0 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) Recep_L_domain PF01030.19 EMR66540.1 - 0.07 13.1 2.7 1.8 8.5 0.6 2.8 3 0 0 3 3 3 0 Receptor L domain LRR_7 PF13504.1 EMR66540.1 - 1.3 9.4 22.6 0.92 9.9 0.1 7.8 9 0 0 9 9 9 0 Leucine rich repeat adh_short PF00106.20 EMR66541.1 - 2.3e-29 102.4 5.8 1.2e-26 93.6 4.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR66541.1 - 1.3e-17 64.4 0.2 8e-16 58.5 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR66541.1 - 4.4e-14 52.5 3.1 2.3e-12 46.9 2.2 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR66541.1 - 0.00092 18.7 0.2 0.0055 16.1 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EMR66541.1 - 0.045 12.8 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Str_synth PF03088.11 EMR66541.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Strictosidine synthase FAD_binding_4 PF01565.18 EMR66545.1 - 2.1e-17 62.8 1.1 3.9e-17 62.0 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR66545.1 - 5.2e-10 39.0 0.5 1.2e-09 37.9 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like Caldesmon PF02029.10 EMR66546.1 - 0.06 11.7 37.6 0.087 11.2 26.1 1.2 1 0 0 1 1 1 0 Caldesmon DUF3347 PF11827.3 EMR66546.1 - 2.4 8.1 13.1 5.3 6.9 9.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) HSP70 PF00012.15 EMR66547.1 - 7.4e-232 770.5 8.5 8.3e-232 770.3 5.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMR66547.1 - 3.6e-15 55.3 0.1 3e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EMR66547.1 - 0.00057 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EMR66547.1 - 0.0096 15.7 2.7 4.4 7.1 0.7 3.6 2 1 0 2 2 2 2 Cell division protein FtsA DUF726 PF05277.7 EMR66549.1 - 1.3e-104 349.8 0.3 1.7e-104 349.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 EMR66549.1 - 1.3e-07 31.7 0.8 3.6e-07 30.2 0.5 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EMR66549.1 - 1.9e-05 24.9 0.0 6.2e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.2 EMR66549.1 - 0.00057 19.6 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EMR66549.1 - 0.031 13.6 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 PE-PPE domain Cutinase PF01083.17 EMR66549.1 - 0.031 14.0 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.20 EMR66549.1 - 0.17 11.4 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Anophelin PF10731.4 EMR66549.1 - 0.46 10.6 3.1 12 6.1 0.4 2.6 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito DUF3419 PF11899.3 EMR66550.1 - 9.5e-155 514.9 0.0 1.3e-154 514.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EMR66550.1 - 1.1e-14 54.4 0.0 2.2e-13 50.2 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR66550.1 - 1.9e-09 38.1 0.0 1.3e-08 35.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR66550.1 - 1.1e-07 31.6 0.0 1.5e-06 27.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR66550.1 - 1.1e-07 31.2 0.0 0.0009 18.4 0.0 2.5 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMR66550.1 - 1.4e-07 31.9 0.0 4.7e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR66550.1 - 6.5e-07 29.3 0.0 0.00026 21.0 0.0 3.6 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR66550.1 - 6.3e-05 23.3 0.0 0.0041 17.5 0.0 3.4 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR66550.1 - 7.3e-05 23.0 0.0 0.00022 21.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMR66550.1 - 0.00075 19.0 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.12 EMR66550.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.12 EMR66550.1 - 0.024 13.6 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.1 EMR66550.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain LRR_4 PF12799.2 EMR66552.1 - 1.8e-40 135.8 30.5 8.1e-14 50.8 1.6 6.7 2 2 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMR66552.1 - 2.8e-19 68.6 34.2 2.6e-08 33.5 1.4 4.7 1 1 3 5 5 5 5 Leucine rich repeat LRR_6 PF13516.1 EMR66552.1 - 7.9e-11 40.8 23.2 0.35 11.0 0.0 9.6 6 4 4 10 10 10 4 Leucine Rich repeat LRR_7 PF13504.1 EMR66552.1 - 3e-09 35.5 15.7 2.8 8.5 0.0 9.2 9 1 0 9 9 9 3 Leucine rich repeat LRR_1 PF00560.28 EMR66552.1 - 3.6e-09 35.3 29.4 2.8 8.3 0.1 10.5 10 1 1 11 11 11 4 Leucine Rich Repeat LRR_9 PF14580.1 EMR66552.1 - 7.6e-08 32.1 11.3 0.00055 19.5 1.1 3.4 1 1 4 5 5 5 4 Leucine-rich repeat UDG PF03167.14 EMR66553.1 - 1.1e-23 83.3 0.0 1.4e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily PQ-loop PF04193.9 EMR66555.1 - 3.7e-18 64.8 1.2 8.7e-08 31.5 0.1 3.3 2 1 0 2 2 2 2 PQ loop repeat TMEM37 PF15108.1 EMR66555.1 - 0.015 14.9 0.8 0.015 14.9 0.6 1.6 2 0 0 2 2 2 0 Voltage-dependent calcium channel gamma-like subunit protein family Cation_efflux PF01545.16 EMR66555.1 - 0.12 11.4 4.4 0.2 10.6 3.1 1.3 1 0 0 1 1 1 0 Cation efflux family DUF2061 PF09834.4 EMR66555.1 - 0.61 10.3 3.3 2.7 8.2 0.5 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2061) Piwi PF02171.12 EMR66556.1 - 1.2e-70 237.9 0.0 7.1e-70 235.3 0.0 1.9 1 1 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EMR66556.1 - 7e-15 54.1 0.1 1.9e-14 52.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EMR66556.1 - 3e-14 52.4 0.0 7.9e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 PAZ domain Colicin_V PF02674.11 EMR66557.1 - 0.49 10.2 3.8 0.32 10.8 0.2 2.1 2 0 0 2 2 2 0 Colicin V production protein Aldo_ket_red PF00248.16 EMR66558.1 - 1.6e-46 158.4 0.0 1.9e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SPX PF03105.14 EMR66559.1 - 2.7 7.7 11.6 14 5.3 7.9 2.1 1 1 0 1 1 1 0 SPX domain Fungal_trans PF04082.13 EMR66561.1 - 3e-10 39.3 0.2 4.2e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_2c PF01411.14 EMR66562.1 - 2.9e-08 32.4 0.2 4e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EMR66562.1 - 1.4e-05 24.8 0.4 2.8e-05 23.9 0.3 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF1857 PF08982.6 EMR66563.1 - 6.6e-45 152.3 0.0 7.4e-45 152.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) DUF4188 PF13826.1 EMR66565.1 - 1.7e-28 99.0 0.3 2.5e-28 98.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 EMR66565.1 - 0.00014 21.0 0.1 0.00019 20.5 0.1 1.2 1 0 0 1 1 1 1 Haem-containing dehydratase LMBR1 PF04791.11 EMR66566.1 - 2.5e-15 56.0 8.6 2.4e-13 49.5 6.0 2.3 1 1 0 1 1 1 1 LMBR1-like membrane protein GRP PF07172.6 EMR66566.1 - 0.062 13.7 0.3 0.062 13.7 0.2 3.6 5 0 0 5 5 5 0 Glycine rich protein family DUF3357 PF11837.3 EMR66566.1 - 0.16 11.8 7.5 6.5 6.6 0.0 5.6 6 1 1 7 7 7 0 Domain of unknown function (DUF3357) DUF1980 PF09323.5 EMR66566.1 - 3.9 7.1 7.6 7.3 6.2 0.4 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF1980) UDPGP PF01704.13 EMR66567.1 - 1.3e-43 149.0 0.0 7.6e-42 143.2 0.0 2.0 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EMR66567.1 - 0.0027 17.7 0.0 0.0055 16.8 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain MFS_1 PF07690.11 EMR66568.1 - 6.7e-41 140.1 34.8 3.5e-39 134.4 7.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR66568.1 - 1e-11 44.1 3.3 1e-11 44.1 2.3 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EMR66568.1 - 7.8e-06 24.5 18.5 6e-05 21.6 2.9 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein Nuc_H_symport PF03825.11 EMR66568.1 - 0.00031 19.6 6.5 0.0005 18.9 0.1 2.2 2 0 0 2 2 2 1 Nucleoside H+ symporter Fungal_trans PF04082.13 EMR66569.1 - 9.8e-06 24.6 0.1 9.6e-05 21.3 0.0 2.1 1 1 1 2 2 2 1 Fungal specific transcription factor domain UbiA PF01040.13 EMR66570.1 - 7.4e-17 61.4 0.1 7.2e-09 35.2 0.1 2.1 1 1 1 2 2 2 2 UbiA prenyltransferase family CENP-B_dimeris PF09026.5 EMR66571.1 - 0.052 13.7 7.1 0.095 12.9 4.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 EMR66571.1 - 2.2 7.8 8.0 3.5 7.2 5.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region E1-E2_ATPase PF00122.15 EMR66572.1 - 4.3e-17 61.9 0.0 9.4e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EMR66572.1 - 3.2e-16 60.4 0.2 4.7e-15 56.5 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMR66572.1 - 5.4e-14 52.7 0.0 1.4e-13 51.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMR66572.1 - 8.2e-08 32.1 0.0 3e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMR66572.1 - 0.017 14.7 0.1 0.062 12.8 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4254 PF14063.1 EMR66572.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Hydrolase_6 PF13344.1 EMR66572.1 - 0.14 12.1 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2512 PF10710.4 EMR66572.1 - 9.4 5.7 9.1 2.7 7.4 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2512) Caleosin PF05042.8 EMR66573.1 - 5.7e-58 195.3 0.0 6.8e-58 195.0 0.0 1.0 1 0 0 1 1 1 1 Caleosin related protein TPR_9 PF13371.1 EMR66574.1 - 0.01 15.6 0.2 0.056 13.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3123 PF11321.3 EMR66574.1 - 4.3 7.6 8.6 21 5.4 3.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Peptidase_M20 PF01546.23 EMR66575.1 - 1.7e-06 27.7 0.1 2.6e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMR66575.1 - 1.2e-05 24.9 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain GMC_oxred_N PF00732.14 EMR66576.1 - 4.3e-62 209.9 0.0 5.7e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR66576.1 - 1.2e-29 103.4 0.0 3.8e-29 101.8 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMR66576.1 - 1.2e-09 37.4 0.0 9e-05 21.4 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR66576.1 - 8.1e-08 31.5 0.0 0.00015 20.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR66576.1 - 7.4e-05 22.7 0.0 0.00095 19.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR66576.1 - 8e-05 21.7 0.4 0.00017 20.6 0.2 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMR66576.1 - 0.00057 19.8 0.2 0.0022 17.9 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR66576.1 - 0.0014 18.7 0.1 0.32 11.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR66576.1 - 0.0033 15.9 0.1 0.0062 15.0 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EMR66576.1 - 0.0085 15.2 0.2 0.014 14.4 0.2 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EMR66576.1 - 0.016 14.9 0.1 0.2 11.4 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EMR66576.1 - 0.017 15.4 0.9 0.052 13.9 0.0 2.3 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMR66576.1 - 0.021 14.7 0.7 0.082 12.9 0.1 2.3 2 1 1 3 3 3 0 TrkA-N domain Trp_halogenase PF04820.9 EMR66576.1 - 0.024 13.2 0.3 0.034 12.7 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.14 EMR66576.1 - 0.03 13.3 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HSCB_C PF07743.8 EMR66577.1 - 5e-17 62.1 2.7 5e-17 62.1 1.9 2.2 3 0 0 3 3 3 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EMR66577.1 - 7e-07 28.8 0.0 1.7e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain TFIIA PF03153.8 EMR66578.1 - 1.8 8.3 7.5 2 8.2 5.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.17 EMR66579.1 - 2.1e-42 145.2 0.0 2.5e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EMR66580.1 - 2e-27 95.3 1.1 3.2e-27 94.7 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR66580.1 - 0.022 14.6 0.0 0.071 13.0 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like Sugar_tr PF00083.19 EMR66581.1 - 1.2e-87 294.3 19.1 2e-87 293.6 13.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR66581.1 - 1.1e-30 106.5 24.2 4.1e-23 81.6 4.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR66581.1 - 4.8e-06 25.2 21.8 1e-05 24.1 1.8 3.4 2 2 1 3 3 3 2 MFS/sugar transport protein MFS_2 PF13347.1 EMR66583.1 - 4.8e-10 38.4 12.0 4.8e-10 38.4 8.3 2.3 2 1 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.10 EMR66583.1 - 0.0072 15.0 2.5 0.018 13.8 1.8 1.7 1 1 0 1 1 1 1 PUCC protein MFS_1_like PF12832.2 EMR66583.1 - 0.02 14.6 0.0 0.11 12.3 0.0 2.3 1 0 0 1 1 1 0 MFS_1 like family SdpI PF13630.1 EMR66583.1 - 4.9 6.9 0.0 4.9 6.9 0.0 4.7 7 1 1 8 8 8 0 SdpI/YhfL protein family HisG PF01634.13 EMR66584.1 - 2.8e-48 163.5 0.0 9.8e-39 132.5 0.0 2.3 2 0 0 2 2 2 2 ATP phosphoribosyltransferase HisG_C PF08029.6 EMR66584.1 - 3.1e-24 84.6 0.3 5.5e-24 83.9 0.2 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain DUF1697 PF08002.6 EMR66584.1 - 0.019 15.0 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) NMT1 PF09084.6 EMR66584.1 - 0.06 12.9 0.0 2.1 7.8 0.0 2.5 2 1 0 2 2 2 0 NMT1/THI5 like MBOAT_2 PF13813.1 EMR66585.1 - 9.4e-16 57.6 6.1 3.9e-15 55.6 4.2 2.0 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family RVT_1 PF00078.22 EMR66586.1 - 1.9e-11 43.7 0.0 3.3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3402 PF11882.3 EMR66587.1 - 7.7e-150 499.4 0.2 3.3e-149 497.4 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EMR66587.1 - 1.8e-30 105.8 9.8 8.9e-24 83.8 0.6 2.6 3 0 0 3 3 3 2 N1221-like protein AAA_23 PF13476.1 EMR66587.1 - 0.64 10.3 5.1 0.86 9.8 1.2 2.3 2 0 0 2 2 2 0 AAA domain DUF2011 PF09428.5 EMR66588.1 - 7.8e-25 87.2 23.6 4.6e-24 84.7 16.4 2.1 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Herpes_LMP2 PF07415.6 EMR66588.1 - 0.069 11.7 0.1 0.081 11.5 0.0 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein NDT80_PhoG PF05224.7 EMR66589.1 - 1.3e-32 113.2 0.0 1.3e-32 113.2 0.0 2.8 4 0 0 4 4 4 1 NDT80 / PhoG like DNA-binding family FCP1_C PF09309.5 EMR66589.1 - 0.15 11.3 10.7 0.57 9.4 1.9 2.4 2 0 0 2 2 2 0 FCP1, C-terminal SPO22 PF08631.5 EMR66590.1 - 1.1e-27 96.7 5.5 1.9e-19 69.8 0.1 3.7 3 1 1 4 4 4 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 EMR66590.1 - 0.014 15.3 1.2 3.8 7.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMR66590.1 - 0.042 13.7 2.2 46 4.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat F_actin_bind PF08919.5 EMR66590.1 - 0.054 13.2 0.1 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 F-actin binding Sec6 PF06046.8 EMR66591.1 - 2.6e-162 540.8 10.3 3.5e-162 540.4 7.1 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 OmdA PF13376.1 EMR66591.1 - 0.0087 15.6 1.3 0.17 11.5 0.0 3.1 3 1 0 3 3 3 1 Bacteriocin-protection, YdeI or OmpD-Associated MutS_III PF05192.13 EMR66591.1 - 0.019 14.7 2.6 3.2 7.4 2.6 3.3 1 1 0 1 1 1 0 MutS domain III Vps53_N PF04100.7 EMR66591.1 - 0.048 12.4 9.1 0.0067 15.2 1.4 2.8 2 1 0 2 2 2 0 Vps53-like, N-terminal NPV_P10 PF05531.7 EMR66591.1 - 0.048 13.9 5.7 12 6.2 0.1 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF104 PF01954.11 EMR66592.1 - 0.092 12.7 0.1 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF104 Abhydrolase_6 PF12697.2 EMR66593.1 - 3.2e-20 73.0 0.1 5.3e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR66593.1 - 5.1e-13 49.1 0.6 6.2e-08 32.4 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR66593.1 - 3.9e-10 39.6 0.2 5.9e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMR66593.1 - 2.8e-07 30.2 0.4 6.2e-07 29.1 0.3 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF3140 PF11338.3 EMR66594.1 - 1.5e-31 108.3 0.3 1.8e-31 108.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) TauD PF02668.11 EMR66595.1 - 2.5e-21 76.5 0.0 4.8e-21 75.6 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DOMON PF03351.12 EMR66596.1 - 0.0035 17.2 0.0 0.0088 15.9 0.0 1.7 1 1 0 1 1 1 1 DOMON domain PHR PF08005.7 EMR66596.1 - 0.038 14.1 0.1 0.064 13.4 0.1 1.4 1 0 0 1 1 1 0 PHR domain Acetyltransf_7 PF13508.1 EMR66598.1 - 0.00044 20.3 0.0 0.0011 19.0 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR66598.1 - 0.00096 19.1 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.1 EMR66598.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.1 EMR66598.1 - 0.021 14.7 0.0 0.047 13.5 0.0 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EMR66598.1 - 0.045 13.5 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GMC_oxred_N PF00732.14 EMR66599.1 - 3.5e-34 118.3 0.0 4.5e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR66599.1 - 4.4e-32 111.3 0.0 7.5e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMR66599.1 - 0.0051 15.7 0.1 0.0082 15.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Tcp10_C PF07202.8 EMR66599.1 - 0.17 11.4 0.1 0.3 10.6 0.1 1.3 1 0 0 1 1 1 0 T-complex protein 10 C-terminus FAD_binding_3 PF01494.14 EMR66600.1 - 3.4e-08 32.9 0.1 0.00087 18.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 EMR66600.1 - 0.00083 19.7 0.2 0.0018 18.6 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR66600.1 - 0.0039 17.1 0.2 0.01 15.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR66600.1 - 0.024 14.5 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR66600.1 - 0.073 11.9 0.2 0.11 11.2 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 EMR66600.1 - 0.13 11.1 3.2 1.3 7.8 1.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase EHN PF06441.7 EMR66601.1 - 4.6e-38 129.5 0.3 6.4e-37 125.9 0.1 2.5 3 0 0 3 3 3 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EMR66601.1 - 1.6e-09 37.9 3.2 1.6e-09 37.9 2.3 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR66601.1 - 3.1e-08 33.4 0.7 8.5e-08 32.0 0.0 2.0 3 0 0 3 3 3 1 alpha/beta hydrolase fold p450 PF00067.17 EMR66602.1 - 6.7e-38 130.3 0.0 8.2e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EMR66603.1 - 6e-22 77.5 0.1 9.4e-22 76.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR66603.1 - 8.6e-08 33.1 0.0 3.2e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.20 EMR66605.1 - 1.4e-13 51.1 0.1 3.1e-13 49.9 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR66605.1 - 2.1e-07 30.7 0.0 7.9e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMR66605.1 - 1e-05 25.4 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR66605.1 - 0.011 15.2 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PhyH PF05721.8 EMR66607.1 - 5.4e-17 62.5 0.0 8.5e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.19 EMR66608.1 - 1.1e-86 291.1 18.3 1.3e-86 290.9 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR66608.1 - 7e-18 64.4 27.3 3.9e-16 58.7 14.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR66608.1 - 1.9e-07 29.8 22.4 0.00014 20.3 1.2 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Glyco_hydro_61 PF03443.9 EMR66609.1 - 1.3e-58 198.3 0.0 1.6e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Chlam_vir PF05475.6 EMR66609.1 - 0.07 12.2 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlamydia virulence protein PGP3-D adh_short PF00106.20 EMR66610.1 - 2e-13 50.5 0.2 2e-12 47.3 0.2 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR66610.1 - 2e-05 24.3 0.5 7.9e-05 22.3 0.3 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR66610.1 - 0.043 13.2 0.0 0.2 11.0 0.0 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR66610.1 - 0.15 12.0 2.0 6.5 6.7 0.2 2.6 2 1 0 2 2 2 0 NADH(P)-binding Chitin_bind_3 PF03067.10 EMR66611.1 - 1.4e-10 41.7 0.4 7.1e-08 32.9 0.3 2.3 1 1 0 1 1 1 1 Chitin binding domain MFS_1 PF07690.11 EMR66612.1 - 3.9e-30 104.7 35.2 6e-30 104.1 23.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily RCR PF12273.3 EMR66612.1 - 0.0097 16.4 0.8 7.2 7.1 0.0 2.5 2 0 0 2 2 2 2 Chitin synthesis regulation, resistance to Congo red DJ-1_PfpI PF01965.19 EMR66613.1 - 1.8e-12 46.9 0.1 9.2e-12 44.6 0.1 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EMR66613.1 - 0.00014 21.1 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase SNO PF01174.14 EMR66613.1 - 0.00025 20.7 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EMR66613.1 - 0.063 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.11 EMR66614.1 - 1.5e-48 165.3 44.2 1.5e-48 165.3 30.6 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR66614.1 - 1.2e-17 63.3 21.3 1.7e-17 62.8 14.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMR66614.1 - 9.7e-15 54.0 10.5 9.7e-15 54.0 7.3 2.8 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 EMR66614.1 - 2.6e-05 22.5 7.4 2.9e-05 22.4 0.2 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector Glyco_hydro_61 PF03443.9 EMR66616.1 - 3.6e-61 206.7 0.0 6.4e-61 205.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ALAD PF00490.16 EMR66617.1 - 0.0041 16.0 0.0 0.0048 15.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase RICH PF05062.7 EMR66617.1 - 0.03 14.4 0.4 0.27 11.3 0.0 2.3 2 0 0 2 2 2 0 RICH domain Spc7 PF08317.6 EMR66617.1 - 0.079 11.6 0.2 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein IZUMO PF15005.1 EMR66617.1 - 0.099 12.6 0.2 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion FlgN PF05130.7 EMR66617.1 - 0.11 12.7 1.8 0.67 10.1 0.8 2.0 1 1 1 2 2 2 0 FlgN protein FliT PF05400.8 EMR66617.1 - 0.14 12.5 1.1 0.25 11.7 0.8 1.4 1 0 0 1 1 1 0 Flagellar protein FliT DUF2827 PF10933.3 EMR66617.1 - 0.14 10.5 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) adh_short PF00106.20 EMR66618.1 - 1e-10 41.7 0.0 2.2e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR66618.1 - 6.1e-08 32.7 0.0 7.9e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR66618.1 - 3.6e-05 23.3 0.0 0.00017 21.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EMR66618.1 - 0.00028 20.6 0.0 0.00073 19.2 0.0 1.7 2 0 0 2 2 2 1 KR domain NmrA PF05368.8 EMR66618.1 - 0.0016 17.7 0.0 0.0032 16.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR66618.1 - 0.019 14.9 0.1 0.32 10.9 0.0 2.4 2 1 0 2 2 2 0 NADH(P)-binding TrkA_N PF02254.13 EMR66618.1 - 0.054 13.5 0.1 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain HAD_2 PF13419.1 EMR66619.1 - 9.4e-21 74.8 0.4 1.9e-18 67.3 0.3 2.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR66619.1 - 0.0084 15.8 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like TPR_16 PF13432.1 EMR66619.1 - 0.063 13.9 0.0 0.19 12.4 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TGFb_propeptide PF00688.13 EMR66619.1 - 0.094 11.9 0.3 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 TGF-beta propeptide ArsR PF09824.4 EMR66619.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator Zip PF02535.17 EMR66619.1 - 0.24 10.3 4.4 0.32 9.9 3.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Alpha-amylase PF00128.19 EMR66620.1 - 1.3e-93 313.8 0.0 1.8e-93 313.4 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EMR66620.1 - 0.034 13.0 0.0 0.049 12.5 0.0 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Mac PF12464.3 EMR66622.1 - 7.9e-21 73.8 0.0 1.8e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Fungal_trans_2 PF11951.3 EMR66622.1 - 9.3e-14 50.8 0.3 1.3e-13 50.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hexapep PF00132.19 EMR66622.1 - 1.3e-12 46.6 7.1 5.7e-11 41.4 3.3 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMR66622.1 - 1.4e-12 46.9 4.7 2.8e-10 39.5 2.3 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase PDR_CDR PF06422.7 EMR66623.1 - 3 7.5 5.5 1 9.0 1.1 2.1 2 1 1 3 3 3 0 CDR ABC transporter DUF1996 PF09362.5 EMR66624.1 - 6.8e-77 258.2 1.0 8.5e-77 257.9 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Fungal_trans PF04082.13 EMR66625.1 - 0.048 12.5 0.1 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ribosomal_60s PF00428.14 EMR66625.1 - 0.28 11.6 6.3 0.32 11.4 0.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Chorion_2 PF03964.10 EMR66625.1 - 3 8.4 8.7 4.7 7.8 0.5 2.5 2 0 0 2 2 2 0 Chorion family 2 POPLD PF08170.7 EMR66626.1 - 8.4e-29 99.2 0.1 8.4e-29 99.2 0.1 2.0 2 1 0 2 2 2 1 POPLD (NUC188) domain Aldo_ket_red PF00248.16 EMR66628.1 - 7.4e-45 152.9 0.0 9e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2062 PF09835.4 EMR66629.1 - 0.021 14.4 0.1 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) MASE1 PF05231.9 EMR66629.1 - 0.036 13.0 0.1 0.055 12.4 0.1 1.2 1 0 0 1 1 1 0 MASE1 Zip PF02535.17 EMR66629.1 - 0.77 8.7 3.4 7.4 5.4 1.3 2.1 1 1 1 2 2 2 0 ZIP Zinc transporter NT-C2 PF10358.4 EMR66630.1 - 1.6e-20 73.0 0.0 3e-16 59.1 0.0 2.3 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins SNARE PF05739.14 EMR66631.1 - 5.1e-18 64.5 0.4 1.8e-17 62.7 0.3 2.0 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EMR66631.1 - 1.2e-06 28.5 0.4 1.2e-06 28.5 0.3 3.4 2 1 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 EMR66631.1 - 0.0015 18.1 2.2 0.016 14.7 0.2 2.4 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-18_N PF10496.4 EMR66631.1 - 0.03 14.1 1.2 0.5 10.2 0.1 2.5 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Host_attach PF10116.4 EMR66631.1 - 0.038 14.2 1.9 0.038 14.2 1.3 1.6 2 0 0 2 2 2 0 Protein required for attachment to host cells Sed5p PF11416.3 EMR66631.1 - 0.043 13.2 0.1 0.043 13.2 0.0 2.5 3 0 0 3 3 3 0 Integral membrane protein Sed5p GMC_oxred_N PF00732.14 EMR66632.1 - 2.9e-61 207.2 0.0 3.8e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR66632.1 - 1.8e-33 115.8 0.0 3.1e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMR66632.1 - 0.00023 20.1 0.0 0.07 12.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR66632.1 - 0.00041 20.3 0.1 0.00098 19.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMR66632.1 - 0.00096 18.1 0.2 0.017 13.9 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EMR66632.1 - 0.0025 16.8 0.1 0.0053 15.7 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EMR66632.1 - 0.0042 15.6 0.2 0.18 10.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EMR66632.1 - 0.014 15.4 0.0 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR66632.1 - 0.023 14.5 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMR66632.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 EMR66632.1 - 0.16 12.3 0.3 2.5 8.5 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.1 EMR66633.1 - 1.4e-16 60.6 0.0 2.2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR66633.1 - 1.3e-14 54.3 0.0 2.2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR66633.1 - 3.1e-14 52.8 0.0 4.1e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR66633.1 - 4.3e-08 33.7 0.0 7.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR66633.1 - 7.7e-08 31.7 0.0 6.9e-06 25.3 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMR66633.1 - 1.2e-07 31.9 0.1 2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR66633.1 - 3e-07 30.8 0.0 5.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMR66633.1 - 5.2e-07 29.0 0.0 7.4e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EMR66633.1 - 3e-06 27.2 0.2 6e-06 26.2 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR66633.1 - 0.0001 21.7 0.0 0.00027 20.3 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase small domain MetW PF07021.7 EMR66633.1 - 0.0017 17.7 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Couple_hipA PF13657.1 EMR66633.1 - 0.0024 18.1 0.0 0.0043 17.3 0.0 1.4 1 0 0 1 1 1 1 HipA N-terminal domain TehB PF03848.9 EMR66633.1 - 0.0062 15.7 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.6 EMR66633.1 - 0.032 12.9 0.1 0.064 11.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) HSP70 PF00012.15 EMR66634.1 - 3.8e-80 269.4 1.0 4.7e-80 269.2 0.7 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMR66634.1 - 5.7e-06 25.1 0.0 8.7e-06 24.5 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EMR66634.1 - 0.024 13.7 0.1 0.11 11.6 0.1 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase CsgE PF10627.4 EMR66634.1 - 0.035 13.9 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Curli assembly protein CsgE AAA_33 PF13671.1 EMR66634.1 - 0.07 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain BRAP2 PF07576.7 EMR66634.1 - 0.078 12.5 0.1 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 YbaB_DNA_bd PF02575.11 EMR66634.1 - 0.099 12.5 0.4 0.56 10.1 0.0 2.4 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family Lipase_GDSL PF00657.17 EMR66636.1 - 4.8e-17 62.5 0.0 5.8e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase p450 PF00067.17 EMR66638.1 - 1.7e-74 251.0 0.0 2.2e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMR66639.1 - 3.9e-49 167.4 0.0 4.9e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 S_100 PF01023.14 EMR66639.1 - 0.064 12.5 0.2 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain GYF PF02213.11 EMR66640.1 - 1.1e-10 40.8 0.2 3.2e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 GYF domain Herpes_US9 PF06072.6 EMR66640.1 - 0.082 12.7 0.4 0.082 12.7 0.3 1.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Reo_sigmaC PF04582.7 EMR66641.1 - 0.00066 18.9 28.1 0.025 13.7 1.7 4.8 3 1 2 5 5 5 3 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EMR66641.1 - 0.003 17.6 15.2 0.0093 16.0 1.1 6.8 3 2 4 7 7 6 3 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.15 EMR66641.1 - 0.02 14.6 0.6 0.02 14.6 0.4 10.6 7 4 2 10 10 9 0 Prefoldin subunit FlaC_arch PF05377.6 EMR66641.1 - 0.024 14.5 1.0 0.024 14.5 0.7 7.3 7 1 1 8 8 8 0 Flagella accessory protein C (FlaC) AAA_13 PF13166.1 EMR66641.1 - 0.13 10.7 61.1 0.13 10.7 17.3 3.7 2 1 2 4 4 4 0 AAA domain CorA PF01544.13 EMR66641.1 - 0.15 11.1 28.4 0.066 12.2 6.4 4.9 4 1 1 5 5 5 0 CorA-like Mg2+ transporter protein MGC-24 PF05283.6 EMR66641.1 - 0.23 11.2 2.3 0.56 9.9 1.1 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) COG2 PF06148.6 EMR66641.1 - 0.62 9.9 35.9 1.9 8.3 0.9 7.6 3 3 5 8 8 8 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.6 EMR66641.1 - 2.7 7.8 27.4 1.8 8.4 0.4 6.2 5 2 1 6 6 6 0 Bacterial protein of unknown function (DUF948) RTBV_P46 PF06216.6 EMR66641.1 - 7.6 5.2 15.2 2 7.1 2.5 3.4 2 1 0 3 3 3 0 Rice tungro bacilliform virus P46 protein CHDCT2 PF08074.6 EMR66641.1 - 8.4 6.0 17.8 0.64 9.7 6.2 3.3 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain Myb_DNA-bind_4 PF13837.1 EMR66642.1 - 0.035 14.2 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Gp_dh_C PF02800.15 EMR66643.1 - 2e-76 254.7 0.1 3e-76 254.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EMR66643.1 - 8e-61 204.4 0.6 1.3e-60 203.7 0.4 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EMR66643.1 - 0.0057 16.5 0.9 0.028 14.3 0.4 2.4 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Peptidase_M28 PF04389.12 EMR66644.1 - 5.9e-17 61.9 0.2 1.3e-16 60.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.10 EMR66644.1 - 1.7e-12 47.0 0.0 3e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EMR66644.1 - 0.00018 21.1 0.4 0.0008 19.0 0.1 2.2 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EMR66644.1 - 0.00071 19.1 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Hpt PF01627.18 EMR66644.1 - 0.045 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Hpt domain UFD1 PF03152.9 EMR66646.1 - 1.6e-66 222.8 0.0 2e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Pyr_redox_3 PF13738.1 EMR66648.1 - 3.6e-26 92.4 0.0 2.7e-24 86.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR66648.1 - 3.9e-17 62.1 0.0 4e-13 49.0 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMR66648.1 - 4.9e-16 59.2 0.0 8.1e-13 48.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR66648.1 - 8.6e-16 57.2 0.0 1.5e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox PF00070.22 EMR66648.1 - 1.7e-10 41.1 0.1 0.031 14.6 0.0 3.5 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR66648.1 - 4.8e-09 36.1 0.8 0.021 14.6 0.0 3.9 3 1 1 4 4 4 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EMR66648.1 - 2.7e-08 33.2 0.9 1.7e-06 27.3 0.2 2.4 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.19 EMR66648.1 - 4.3e-07 29.1 2.2 0.17 10.7 0.0 3.9 3 2 0 4 4 4 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EMR66648.1 - 1.1e-06 28.7 0.0 0.006 16.6 0.0 3.2 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 EMR66648.1 - 2.9e-06 27.2 0.0 2.3e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EMR66648.1 - 9.2e-06 24.7 0.5 0.28 10.0 0.0 3.3 3 1 0 3 3 3 2 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EMR66648.1 - 1.3e-05 24.3 0.0 0.016 14.1 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EMR66648.1 - 4.3e-05 22.5 0.2 0.012 14.5 0.0 3.1 3 1 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EMR66648.1 - 0.0001 21.5 0.0 0.062 12.4 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EMR66648.1 - 0.00057 19.5 0.0 0.17 11.5 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EMR66648.1 - 0.0016 17.0 0.1 0.21 9.9 0.0 3.1 4 0 0 4 4 4 1 HI0933-like protein F420_oxidored PF03807.12 EMR66648.1 - 0.002 18.5 0.0 1.6 9.1 0.0 3.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent FAD_oxidored PF12831.2 EMR66648.1 - 0.0021 17.2 0.1 0.15 11.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase ThiF PF00899.16 EMR66648.1 - 0.0047 16.7 0.6 4 7.2 0.0 2.6 2 0 0 2 2 2 2 ThiF family Malic_M PF03949.10 EMR66648.1 - 0.012 15.1 0.1 3.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain NAD_binding_7 PF13241.1 EMR66648.1 - 0.014 15.6 0.0 0.75 10.0 0.0 2.7 3 0 0 3 3 2 0 Putative NAD(P)-binding ApbA PF02558.11 EMR66648.1 - 0.034 13.5 0.0 0.11 11.9 0.0 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 EMR66648.1 - 0.042 13.4 0.0 5.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EMR66648.1 - 0.074 12.1 0.1 1.3 8.0 0.0 2.5 3 0 0 3 3 3 0 Thi4 family IlvN PF07991.7 EMR66648.1 - 0.1 11.9 0.0 1.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 EMR66648.1 - 0.13 12.0 0.0 16 5.1 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TIP49 PF06068.8 EMR66649.1 - 4.7e-171 568.8 1.8 5.5e-171 568.6 1.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EMR66649.1 - 7e-08 32.7 0.2 3.6e-05 23.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMR66649.1 - 5.9e-07 28.7 0.3 0.00012 21.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EMR66649.1 - 2.4e-06 26.6 0.3 3.8e-06 25.9 0.2 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 EMR66649.1 - 0.00032 20.8 0.1 0.87 9.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EMR66649.1 - 0.00069 19.6 0.1 0.0037 17.2 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 EMR66649.1 - 0.00086 18.5 0.8 0.0083 15.3 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EMR66649.1 - 0.0057 16.5 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EMR66649.1 - 0.029 13.7 0.1 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMR66649.1 - 0.033 13.9 0.6 0.12 12.1 0.3 2.0 1 1 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 EMR66649.1 - 0.042 13.3 0.0 7.5 5.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 EMR66649.1 - 0.047 13.4 0.1 3 7.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EMR66649.1 - 0.084 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RRP14 PF15459.1 EMR66650.1 - 0.15 12.1 1.7 0.34 11.0 1.2 1.6 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 p450 PF00067.17 EMR66651.1 - 4.3e-44 150.7 0.0 5.5e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HemY_N PF07219.8 EMR66652.1 - 0.013 15.0 3.1 0.019 14.5 1.7 1.7 2 1 0 2 2 2 0 HemY protein N-terminus p450 PF00067.17 EMR66653.1 - 2.3e-40 138.5 0.0 3.6e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ORC6 PF05460.8 EMR66654.1 - 0.14 11.2 2.6 0.15 11.0 1.8 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) vMSA PF00695.14 EMR66654.1 - 0.23 10.6 0.6 0.24 10.5 0.4 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus HTH_12 PF08461.5 EMR66655.1 - 0.042 13.5 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF936 PF06075.7 EMR66655.1 - 0.21 10.4 3.1 0.24 10.2 2.2 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) p450 PF00067.17 EMR66656.1 - 3.5e-27 95.0 0.0 7.6e-27 93.9 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 DUF917 PF06032.7 EMR66657.1 - 1.2e-108 362.8 0.9 1.2e-108 362.8 0.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EMR66657.1 - 7e-53 179.6 5.5 8.5e-51 172.7 1.0 4.1 3 2 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EMR66657.1 - 3.2e-28 98.4 2.3 4.3e-26 91.4 0.0 3.2 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 EMR66657.1 - 9.5e-06 25.0 4.4 0.00057 19.2 0.1 3.3 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.1 EMR66657.1 - 0.0014 17.0 5.0 0.02 13.2 0.0 2.5 3 0 0 3 3 3 2 MutL protein StbA PF06406.6 EMR66657.1 - 0.0052 15.7 0.9 0.64 8.9 0.1 2.4 2 0 0 2 2 2 2 StbA protein DUF1640 PF07798.6 EMR66658.1 - 8e-55 185.6 6.9 8.8e-55 185.4 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Peptidase_S46 PF10459.4 EMR66658.1 - 0.018 13.5 2.0 0.019 13.3 1.4 1.0 1 0 0 1 1 1 0 Peptidase S46 Syntaxin PF00804.20 EMR66658.1 - 0.023 14.8 4.6 0.023 14.8 3.2 2.3 1 1 1 2 2 2 0 Syntaxin Lzipper-MIP1 PF14389.1 EMR66658.1 - 0.048 13.7 5.1 0.52 10.4 0.0 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 HrpB7 PF09486.5 EMR66658.1 - 0.066 13.1 5.4 0.088 12.7 3.3 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) cwf21 PF08312.7 EMR66658.1 - 0.085 12.7 4.2 0.38 10.6 2.9 2.2 1 1 0 1 1 1 0 cwf21 domain DUF1383 PF07134.6 EMR66658.1 - 0.27 10.0 2.1 0.26 10.1 0.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1383) DUF342 PF03961.8 EMR66658.1 - 1.3 7.4 6.2 1.4 7.2 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FTA4 PF13093.1 EMR66658.1 - 2.4 7.5 9.4 4.3 6.7 6.5 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Matrilin_ccoil PF10393.4 EMR66658.1 - 6.2 6.2 6.6 16 4.9 0.5 3.5 3 1 1 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Lactamase_B_2 PF12706.2 EMR66659.1 - 1.1e-33 116.4 0.0 1.5e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMR66659.1 - 6.6e-11 42.1 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMR66659.1 - 1.1e-07 31.6 0.0 9.4e-07 28.6 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily MPC PF03650.8 EMR66660.1 - 6e-33 113.3 0.0 7.1e-33 113.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Glyco_transf_15 PF01793.11 EMR66661.1 - 7.1e-141 468.9 6.6 8.8e-141 468.6 4.6 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.14 EMR66661.1 - 0.028 14.2 0.7 0.028 14.2 0.5 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Clathrin PF00637.15 EMR66662.1 - 8.2e-201 657.6 30.9 1.6e-32 112.0 1.1 7.9 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EMR66662.1 - 8.5e-30 102.4 0.1 3e-29 100.6 0.0 2.1 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 EMR66662.1 - 1.4e-28 97.1 3.4 0.0027 17.8 0.0 7.6 7 0 0 7 7 7 6 Clathrin propeller repeat TPR_12 PF13424.1 EMR66662.1 - 2.7e-06 27.1 0.7 0.34 10.8 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMR66662.1 - 8.3e-06 25.2 7.2 4.4 7.3 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat Clathrin-link PF09268.5 EMR66662.1 - 0.035 13.1 0.2 1.1 8.3 0.0 2.7 2 0 0 2 2 2 0 Clathrin, heavy-chain linker TPR_14 PF13428.1 EMR66662.1 - 0.053 14.1 17.0 41 5.1 0.0 9.2 11 1 0 11 11 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMR66662.1 - 0.057 13.7 4.6 15 6.0 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Nucleoporin_N PF08801.6 EMR66662.1 - 0.12 11.0 0.2 0.65 8.6 0.1 2.0 2 1 1 3 3 3 0 Nup133 N terminal like TPR_2 PF07719.12 EMR66662.1 - 0.93 9.5 10.3 5.7 7.1 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMR66662.1 - 0.97 9.1 8.8 5.7 6.7 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Ribosomal_L5_C PF00673.16 EMR66664.1 - 3.3e-22 78.0 0.0 4.6e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EMR66664.1 - 1.1e-19 69.9 0.1 3.5e-19 68.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 Sin_N PF04801.8 EMR66665.1 - 2.7e-19 69.3 0.2 2.5e-09 36.5 0.0 2.5 2 1 0 2 2 2 2 Sin-like protein conserved region LSM PF01423.17 EMR66666.1 - 6.5e-18 64.0 0.0 1e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain RRM_6 PF14259.1 EMR66667.1 - 2.9e-05 23.9 0.0 6.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR66667.1 - 0.0018 17.8 0.0 0.0095 15.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhoGAP PF00620.22 EMR66668.1 - 1.2e-42 145.1 0.4 2.5e-42 144.0 0.3 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EMR66668.1 - 2.5e-11 43.6 0.0 5.4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMR66668.1 - 6.3e-08 32.8 0.0 1.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EMR66668.1 - 0.0083 16.1 0.0 0.082 12.9 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain NAD_binding_9 PF13454.1 EMR66669.1 - 1.9e-06 27.7 1.1 0.013 15.3 0.0 2.8 2 1 1 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EMR66669.1 - 0.00026 20.9 0.2 0.00072 19.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EMR66669.1 - 0.00027 20.0 0.1 0.15 11.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.19 EMR66669.1 - 0.00033 19.8 0.0 0.0004 19.5 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EMR66669.1 - 0.00037 19.5 1.1 0.032 13.1 0.2 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMR66669.1 - 0.0042 16.0 0.0 0.28 10.0 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EMR66669.1 - 0.011 16.0 1.1 0.19 12.1 0.1 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR66669.1 - 0.17 11.7 1.6 0.46 10.3 0.1 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PAT1 PF09770.4 EMR66670.1 - 2.2e-232 773.7 8.2 2.7e-232 773.4 5.7 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Transp_cyt_pur PF02133.10 EMR66671.1 - 3.1e-80 269.8 38.9 4.6e-80 269.3 27.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2516 PF10724.4 EMR66671.1 - 2 8.4 8.4 6.6 6.8 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2516) MFS_1 PF07690.11 EMR66672.1 - 0.87 8.2 6.8 0.32 9.6 0.2 2.1 1 1 0 1 1 1 0 Major Facilitator Superfamily zf-LITAF-like PF10601.4 EMR66673.1 - 0.28 11.0 2.5 0.81 9.5 1.7 1.8 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain DUF2714 PF10896.3 EMR66673.1 - 0.48 10.2 4.0 0.95 9.2 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2714) Abhydrolase_6 PF12697.2 EMR66674.1 - 3.8e-10 40.0 0.0 4.3e-07 30.0 0.0 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR66674.1 - 1.4e-06 27.9 0.1 3.9e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR66674.1 - 0.0023 17.7 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family RNA_ligase PF09414.5 EMR66675.1 - 1.6e-18 67.1 0.0 3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_M PF01068.16 EMR66675.1 - 0.0068 15.7 0.1 0.82 9.0 0.1 3.6 2 1 0 2 2 2 1 ATP dependent DNA ligase domain Abhydrolase_6 PF12697.2 EMR66676.1 - 2.6e-22 79.8 0.2 3.2e-22 79.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR66676.1 - 2.3e-18 66.3 0.1 3.7e-18 65.6 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR66676.1 - 0.00021 20.5 0.1 0.028 13.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.7 EMR66676.1 - 0.00038 19.0 0.0 0.042 12.3 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 EMR66676.1 - 0.0043 16.6 0.0 0.67 9.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 EMR66676.1 - 0.036 13.3 0.0 0.23 10.7 0.0 2.0 2 1 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EMR66676.1 - 0.06 12.7 0.0 0.24 10.7 0.0 2.0 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 EMR66676.1 - 0.1 12.1 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein adh_short_C2 PF13561.1 EMR66677.1 - 3.4e-15 56.4 0.5 4e-15 56.2 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR66677.1 - 5.6e-10 39.3 6.1 8.9e-10 38.7 4.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR66677.1 - 0.00013 21.7 2.1 0.00025 20.7 1.5 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR66677.1 - 0.037 13.4 2.4 0.22 10.9 0.2 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EMR66677.1 - 0.037 13.1 1.0 0.048 12.7 0.1 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EMR66677.1 - 0.044 13.5 2.3 0.13 12.1 1.6 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MTS PF05175.9 EMR66677.1 - 0.045 13.1 0.1 0.073 12.4 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain NAD_binding_7 PF13241.1 EMR66677.1 - 0.047 13.9 0.1 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FLgD_tudor PF13861.1 EMR66677.1 - 0.12 12.3 0.6 0.23 11.4 0.4 1.5 1 0 0 1 1 1 0 FlgD Tudor-like domain NmrA PF05368.8 EMR66678.1 - 1.8e-30 105.8 0.0 2.5e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR66678.1 - 4.8e-09 36.4 0.1 7.9e-09 35.7 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EMR66678.1 - 0.0004 20.2 0.2 0.00078 19.3 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EMR66678.1 - 0.00041 20.6 0.3 0.0009 19.5 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EMR66678.1 - 0.00073 19.2 0.1 0.0016 18.1 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR66678.1 - 0.00094 19.1 0.2 0.0017 18.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 EMR66678.1 - 0.0019 17.2 0.4 0.006 15.6 0.2 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 EMR66678.1 - 0.0066 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR66678.1 - 0.043 12.5 0.4 0.072 11.7 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EMR66678.1 - 0.085 13.3 0.0 0.37 11.2 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_5 PF07994.7 EMR66678.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Glyco_hydro_43 PF04616.9 EMR66679.1 - 2.6e-60 203.9 0.2 3.3e-60 203.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Peptidase_M20 PF01546.23 EMR66680.1 - 2.3e-17 63.1 0.1 3.5e-17 62.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 EMR66680.1 - 0.0028 17.3 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.9 EMR66680.1 - 0.022 14.4 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase dimerisation domain Hce2 PF14856.1 EMR66681.1 - 1.1e-07 31.6 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor RTA1 PF04479.8 EMR66682.1 - 1.2e-54 185.2 11.1 1.5e-54 184.8 7.7 1.1 1 0 0 1 1 1 1 RTA1 like protein Kei1 PF08552.6 EMR66682.1 - 0.028 14.0 0.2 0.028 14.0 0.1 1.8 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 TrbE PF11100.3 EMR66682.1 - 0.65 9.8 6.1 1.2 8.9 0.0 3.1 3 0 0 3 3 3 0 Conjugal transfer protein TrbE DctQ PF04290.7 EMR66682.1 - 1 9.1 16.8 0.076 12.7 1.5 2.8 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Tetraspannin PF00335.15 EMR66682.1 - 1 8.5 14.5 0.48 9.6 0.6 2.5 2 1 1 3 3 3 0 Tetraspanin family DUF3112 PF11309.3 EMR66682.1 - 1.2 8.9 11.6 3.1 7.5 8.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) DUF2975 PF11188.3 EMR66682.1 - 2.9 7.6 15.2 0.12 12.1 4.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2975) Herpes_capsid PF06112.6 EMR66683.1 - 2.3 8.2 12.5 5.2 7.1 8.7 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Macoilin PF09726.4 EMR66683.1 - 5.4 5.1 5.8 6.3 4.9 4.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S8 PF00082.17 EMR66684.1 - 5.9e-43 147.0 7.7 7.2e-43 146.7 5.4 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMR66684.1 - 0.0001 22.7 0.1 0.00028 21.4 0.1 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 RRM_1 PF00076.17 EMR66684.1 - 0.086 12.4 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRI12 PF06609.8 EMR66686.1 - 1.5e-129 432.9 33.5 7.6e-79 265.4 5.2 3.0 1 1 2 3 3 3 3 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EMR66686.1 - 2.2e-15 56.2 43.5 2.2e-15 56.2 30.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR66686.1 - 1.7e-10 40.0 7.3 1.7e-10 40.0 5.0 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EMR66686.1 - 1.2e-05 23.8 0.6 1.2e-05 23.8 0.4 3.6 1 1 2 3 3 3 1 MFS/sugar transport protein ADH_N PF08240.7 EMR66687.1 - 8.2e-27 93.1 0.9 1.4e-26 92.3 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR66687.1 - 1e-20 73.6 0.6 1e-20 73.6 0.4 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR66687.1 - 4e-16 60.0 0.6 9.4e-16 58.8 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-DHHC PF01529.15 EMR66687.1 - 0.67 9.3 5.5 0.98 8.7 3.8 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Prim_Zn_Ribbon PF08273.7 EMR66689.1 - 0.13 12.3 0.5 7.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Sugar_tr PF00083.19 EMR66690.1 - 1.7e-68 231.2 21.2 2.3e-67 227.5 14.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR66690.1 - 2.5e-15 56.0 31.0 4.5e-10 38.7 7.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily PspC PF04024.7 EMR66690.1 - 0.56 9.7 8.0 0.19 11.1 0.6 3.3 3 0 0 3 3 3 0 PspC domain DUF3007 PF11460.3 EMR66690.1 - 1.5 8.9 4.8 11 6.2 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3007) NUDIX_2 PF13869.1 EMR66691.1 - 1.4e-81 272.3 0.0 1.7e-81 272.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase PDEase_I PF00233.14 EMR66692.1 - 3.5e-46 157.8 0.0 9.6e-42 143.3 0.0 2.1 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase UPF0047 PF01894.12 EMR66693.1 - 1.8e-40 137.3 0.0 2.3e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Mito_fiss_reg PF05308.6 EMR66693.1 - 0.68 9.2 4.9 0.94 8.7 3.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EMR66693.1 - 0.9 8.7 3.5 1.2 8.3 2.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.20 EMR66694.1 - 7.8e-47 159.5 0.0 9.5e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR66694.1 - 9.4e-16 57.6 0.0 1.3e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR66694.1 - 3.3e-09 36.1 0.0 4.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EMR66694.1 - 6.9e-05 22.2 0.3 0.00013 21.3 0.1 1.5 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EMR66694.1 - 0.00013 21.7 0.1 0.00023 20.9 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EMR66694.1 - 0.00027 20.0 0.1 0.00044 19.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M16_C PF05193.16 EMR66695.1 - 2.1e-32 112.2 0.0 1.2e-19 70.7 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMR66695.1 - 5.2e-32 110.6 0.8 2.5e-31 108.4 0.0 2.6 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) UCH PF00443.24 EMR66696.1 - 4.6e-58 196.4 0.0 1.5e-57 194.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMR66696.1 - 6.8e-15 55.2 0.0 2.4e-10 40.3 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-ribbon_3 PF13248.1 EMR66696.1 - 0.1 11.8 1.2 1.3 8.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Dynamin_N PF00350.18 EMR66697.1 - 2.3e-13 50.3 1.2 2.6e-12 46.8 0.0 3.0 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EMR66697.1 - 5.8e-06 26.2 0.4 0.013 15.4 0.0 3.2 2 1 0 3 3 3 2 50S ribosome-binding GTPase DUF258 PF03193.11 EMR66697.1 - 3.3e-05 23.1 0.1 0.0018 17.4 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function, DUF258 DUF2458 PF10454.4 EMR66697.1 - 0.00013 21.9 2.5 0.00013 21.9 1.8 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2458) ABC_tran PF00005.22 EMR66697.1 - 0.0027 18.0 3.1 0.0027 18.0 2.2 4.1 3 2 0 3 3 3 1 ABC transporter PBP1_TM PF14812.1 EMR66697.1 - 0.013 15.7 7.2 0.013 15.7 5.0 3.9 3 1 1 4 4 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Adeno_IVa2 PF02456.10 EMR66697.1 - 0.013 14.1 0.0 0.025 13.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein GTP_EFTU PF00009.22 EMR66697.1 - 0.017 14.5 0.1 0.15 11.4 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMR66697.1 - 0.05 13.7 0.1 0.61 10.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EMR66697.1 - 0.21 11.4 2.7 1.2 8.9 0.2 3.5 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EMR66697.1 - 0.3 11.2 1.8 3.1 7.9 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_10 PF12846.2 EMR66697.1 - 1.3 8.3 7.6 1.5 8.2 0.0 3.4 3 1 0 4 4 4 0 AAA-like domain zf-CHCC PF10276.4 EMR66698.1 - 2.6e-10 39.9 0.2 3.8e-10 39.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain Glyco_hydro_31 PF01055.21 EMR66699.1 - 2.7e-161 537.3 1.9 3.2e-161 537.0 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 FAD_binding_2 PF00890.19 EMR66700.1 - 2.2e-34 119.0 0.0 3.1e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMR66700.1 - 0.00041 20.2 0.0 0.027 14.3 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR66700.1 - 0.0065 15.4 0.0 0.028 13.3 0.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Cadherin_2 PF08266.7 EMR66700.1 - 0.085 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Cadherin-like NUMOD1 PF07453.8 EMR66700.1 - 0.097 12.5 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 NUMOD1 domain EthD PF07110.6 EMR66701.1 - 2.6e-08 34.6 0.1 2.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 EthD domain Tannase PF07519.6 EMR66702.1 - 1.3e-93 314.3 0.2 2.7e-93 313.2 0.1 1.5 1 1 0 1 1 1 1 Tannase and feruloyl esterase KR PF08659.5 EMR66702.1 - 4.7e-59 199.0 0.2 2.5e-58 196.7 0.0 2.3 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EMR66702.1 - 4.2e-53 180.7 0.1 7.8e-53 179.8 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EMR66702.1 - 7e-46 156.1 0.7 4e-45 153.7 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase ketoacyl-synt PF00109.21 EMR66702.1 - 1.3e-39 136.2 0.0 3.5e-27 95.4 0.0 2.9 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EMR66702.1 - 3.3e-39 134.8 0.0 5.9e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EMR66702.1 - 8.4e-39 132.0 0.1 2.5e-38 130.5 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EMR66702.1 - 1.9e-20 73.1 0.0 5.6e-20 71.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR66702.1 - 1.4e-13 50.8 0.0 5.3e-13 49.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR66702.1 - 2.9e-12 46.4 0.0 7.6e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EMR66702.1 - 3.3e-12 46.0 5.3 6.3e-11 41.9 0.2 3.5 3 1 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 EMR66702.1 - 1.1e-10 41.8 0.0 5e-10 39.7 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR66702.1 - 1.9e-10 41.3 0.0 6e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EMR66702.1 - 1.2e-08 35.9 0.0 5e-07 30.6 0.0 3.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.13 EMR66702.1 - 9.3e-07 28.1 0.0 2.7e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMR66702.1 - 6.9e-06 26.3 0.0 2.2e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR66702.1 - 1.3e-05 25.3 0.0 4.2e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EMR66702.1 - 0.00029 20.5 0.1 0.00083 19.0 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PIF1 PF05970.9 EMR66702.1 - 0.0026 16.7 0.0 0.0047 15.9 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase Polysacc_synt_2 PF02719.10 EMR66702.1 - 0.022 13.6 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_16 PF10294.4 EMR66702.1 - 0.03 13.7 0.0 0.086 12.2 0.0 1.7 1 1 0 1 1 1 0 Putative methyltransferase NAS PF03059.11 EMR66702.1 - 0.044 12.9 0.0 0.086 11.9 0.0 1.4 1 0 0 1 1 1 0 Nicotianamine synthase protein NodS PF05401.6 EMR66702.1 - 0.053 12.9 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) UvrD_C_2 PF13538.1 EMR66702.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Methyltransf_23 PF13489.1 EMR66704.1 - 4.4e-12 46.0 0.0 9.9e-12 44.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR66704.1 - 5.3e-09 36.4 0.0 6.9e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR66704.1 - 6.8e-06 25.7 0.0 2.2e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR66704.1 - 1.3e-05 25.6 0.0 3.5e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR66704.1 - 8.9e-05 23.0 0.1 0.0051 17.3 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR66704.1 - 0.00013 21.2 0.0 0.00019 20.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EMR66704.1 - 0.0092 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR66704.1 - 0.01 16.1 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF4518 PF15008.1 EMR66705.1 - 0.093 11.7 0.1 0.093 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Kelch_5 PF13854.1 EMR66707.1 - 5.9e-13 48.4 2.1 1.5e-09 37.6 0.2 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 EMR66707.1 - 8.5e-05 22.6 14.5 0.0025 17.9 0.1 5.4 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_4 PF13418.1 EMR66707.1 - 0.00084 19.0 11.2 0.029 14.1 0.4 4.0 2 2 1 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EMR66707.1 - 0.003 17.2 8.5 2.2 8.1 0.2 4.4 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 EMR66707.1 - 0.0053 16.8 7.7 1.1 9.5 0.1 3.7 3 1 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 EMR66707.1 - 8.6 6.0 12.5 3.7 7.1 1.8 3.8 3 1 0 3 3 3 0 Kelch motif Glyco_hydro_6 PF01341.12 EMR66709.1 - 2e-94 316.3 1.5 2.5e-94 316.0 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Sigma54_activ_2 PF14532.1 EMR66709.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MFS_1 PF07690.11 EMR66710.1 - 6.2e-07 28.4 6.6 4.8e-06 25.5 4.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MARVEL PF01284.18 EMR66712.1 - 5.1e-15 55.5 12.6 6.2e-15 55.2 8.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2976 PF11190.3 EMR66712.1 - 0.12 11.8 2.1 0.35 10.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Colicin_V PF02674.11 EMR66712.1 - 3.8 7.3 11.7 7.1 6.4 3.8 2.1 1 1 1 2 2 2 0 Colicin V production protein MFS_1 PF07690.11 EMR66713.1 - 1.5e-10 40.3 9.3 1.9e-05 23.5 0.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OST3_OST6 PF04756.8 EMR66714.1 - 4e-24 84.9 0.2 5.7e-24 84.4 0.2 1.1 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EMR66714.1 - 0.0056 16.3 0.0 0.009 15.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin SbcCD_C PF13558.1 EMR66715.1 - 0.081 12.8 1.2 0.14 12.0 0.6 1.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Sugar_tr PF00083.19 EMR66717.1 - 7.6e-80 268.6 16.6 2.9e-51 174.4 5.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR66717.1 - 1.1e-19 70.3 29.3 2.3e-14 52.8 1.4 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EMR66717.1 - 0.0009 18.0 0.1 0.002 16.8 0.0 1.5 1 1 0 1 1 1 1 BT1 family Phage_holin_2 PF04550.7 EMR66717.1 - 0.07 13.2 0.6 0.18 11.9 0.4 1.7 1 0 0 1 1 1 0 Phage holin family 2 MFS_1 PF07690.11 EMR66718.1 - 6.9e-39 133.5 34.2 6.9e-39 133.5 23.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4400 PF14348.1 EMR66718.1 - 0.46 9.8 14.6 1.5 8.1 0.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4400) Vma12 PF11712.3 EMR66718.1 - 5.6 6.6 10.9 40 3.9 0.1 2.7 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pkinase PF00069.20 EMR66720.1 - 7.5e-48 162.9 0.0 3.6e-47 160.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR66720.1 - 9.8e-27 93.6 0.0 4.2e-26 91.5 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR66720.1 - 0.0043 16.0 0.0 0.011 14.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like DIOX_N PF14226.1 EMR66721.1 - 2.1e-24 86.2 0.2 3.5e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMR66721.1 - 3.5e-15 56.0 0.0 6.5e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Patatin PF01734.17 EMR66722.1 - 3.2e-05 23.9 0.0 4.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase UQ_con PF00179.21 EMR66723.1 - 1.8e-46 157.0 0.0 2e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMR66723.1 - 0.012 15.3 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 EMR66723.1 - 0.089 12.6 0.4 0.18 11.6 0.3 1.6 1 1 0 1 1 1 0 RWD domain DUF530 PF04409.7 EMR66724.1 - 0.015 13.4 0.1 0.029 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF530) AIM24 PF01987.12 EMR66725.1 - 4e-48 163.7 0.2 5e-48 163.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Reo_sigmaC PF04582.7 EMR66726.1 - 3.9 6.5 17.0 0.8 8.8 3.6 2.9 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Ureidogly_hydro PF04115.7 EMR66727.1 - 1.6e-46 157.6 0.0 2.2e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate hydrolase DUF758 PF05527.6 EMR66728.1 - 0.03 13.9 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF758) MRC1 PF09444.5 EMR66729.1 - 3.8e-38 131.0 15.6 3.8e-38 131.0 10.8 7.8 6 2 2 8 8 8 1 MRC1-like domain DUF267 PF03268.9 EMR66729.1 - 1.6 7.4 1.5 2.3 6.9 1.0 1.1 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 Gly_rich PF12810.2 EMR66729.1 - 2.9 7.4 21.3 0.072 12.6 9.4 2.2 2 0 0 2 2 2 0 Glycine rich protein Med1 PF10744.4 EMR66732.1 - 2e-37 128.9 0.1 4.5e-24 84.9 0.0 2.1 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 Cyt-b5 PF00173.23 EMR66733.1 - 2.3e-17 62.5 0.0 5.3e-14 51.7 0.0 3.6 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_1 PF00667.15 EMR66733.1 - 2.7e-12 46.5 0.0 5.8e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain IDO PF01231.13 EMR66733.1 - 5.9e-10 38.1 0.0 5e-09 35.0 0.0 2.1 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase NAD_binding_1 PF00175.16 EMR66733.1 - 1.1e-08 35.5 0.0 3.5e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Peptidase_S6 PF02395.11 EMR66734.1 - 0.041 12.0 0.0 0.057 11.5 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin A1 protease Mucin PF01456.12 EMR66734.1 - 1.2 8.8 15.9 1.8 8.3 11.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein ArsB PF02040.10 EMR66735.1 - 3.3e-10 39.4 23.4 4e-07 29.3 8.8 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein Spc97_Spc98 PF04130.8 EMR66736.1 - 1.2e-100 337.3 1.0 1.6e-100 337.0 0.7 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Ribosomal_60s PF00428.14 EMR66736.1 - 0.073 13.4 0.5 3.7 8.0 0.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein APG17 PF04108.7 EMR66736.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 SAGA-Tad1 PF12767.2 EMR66737.1 - 3.8e-28 98.8 0.0 5e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Peptidase_S8 PF00082.17 EMR66738.1 - 1.3e-41 142.5 5.5 2.1e-41 141.9 3.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMR66738.1 - 8.3e-11 42.3 0.0 1.5e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 EMP24_GP25L PF01105.19 EMR66740.1 - 1.6e-52 177.9 0.0 1.8e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3328 PF11807.3 EMR66741.1 - 8.2e-32 110.6 2.8 9.1e-32 110.4 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) HET PF06985.6 EMR66742.1 - 1.3e-22 80.4 0.0 2.6e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4560 PF15118.1 EMR66742.1 - 0.025 14.3 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4560) HET PF06985.6 EMR66743.1 - 1.6e-22 80.1 0.9 4.2e-19 69.0 0.1 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EMR66743.1 - 1.2e-14 54.3 0.0 3.1e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMR66743.1 - 5.8e-13 47.9 0.1 4.2e-08 32.6 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EMR66743.1 - 1e-10 41.7 0.0 3.3e-07 30.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR66743.1 - 2.6e-09 37.0 0.3 7.4e-09 35.5 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR66743.1 - 2.8e-09 36.3 0.5 3.7e-07 29.7 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat DNA_methylase PF00145.12 EMR66744.1 - 6.4e-14 51.8 0.7 1.9e-05 23.9 0.0 3.7 3 1 0 3 3 3 2 C-5 cytosine-specific DNA methylase SNF2_N PF00176.18 EMR66744.1 - 1.1e-12 47.4 0.0 2.2e-08 33.2 0.0 2.9 3 0 0 3 3 3 2 SNF2 family N-terminal domain HC2 PF07382.6 EMR66744.1 - 2e-05 24.5 17.1 5.1e-05 23.2 11.9 1.6 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Peptidase_M43 PF05572.8 EMR66745.1 - 7.6e-09 35.3 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EMR66745.1 - 0.0003 20.7 0.1 0.00046 20.1 0.0 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMR66745.1 - 0.0051 17.3 1.2 0.0083 16.6 0.8 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EMR66745.1 - 0.0056 15.5 0.8 0.0085 15.0 0.6 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_4 PF13583.1 EMR66745.1 - 0.023 14.2 0.1 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMR66745.1 - 0.034 14.2 1.9 0.039 14.0 1.3 1.3 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CorA PF01544.13 EMR66747.1 - 9.3e-09 34.7 0.3 1.5e-08 34.0 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DnaJ PF00226.26 EMR66748.1 - 1.9e-17 62.7 0.3 3.6e-17 61.8 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain ABC1 PF03109.11 EMR66749.1 - 4.5e-32 110.5 0.0 7.8e-32 109.7 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Asn_synthase PF00733.16 EMR66750.1 - 4.8e-69 232.7 0.0 6.6e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EMR66750.1 - 3e-36 123.8 0.0 4.8e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EMR66750.1 - 8.4e-29 100.2 0.0 4.5e-28 97.8 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EMR66750.1 - 6.2e-07 28.8 0.0 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EMR66750.1 - 0.00059 18.8 0.0 0.0014 17.6 0.0 1.7 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 EMR66750.1 - 0.0047 15.6 0.0 0.053 12.2 0.0 2.2 1 1 2 3 3 3 1 Glutamine amidotransferases class-II Snf7 PF03357.16 EMR66751.1 - 3.1e-28 98.2 22.8 3.1e-28 98.2 15.8 2.0 1 1 1 2 2 2 1 Snf7 MutS_III PF05192.13 EMR66751.1 - 0.0065 16.2 3.2 0.0092 15.7 2.2 1.2 1 0 0 1 1 1 1 MutS domain III Allexi_40kDa PF05549.6 EMR66751.1 - 0.069 12.4 8.6 0.12 11.6 6.0 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein Macro_2 PF14519.1 EMR66751.1 - 0.12 11.4 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Macro-like domain HK97-gp10_like PF04883.7 EMR66751.1 - 6.2 7.8 6.8 6.4 7.7 0.1 2.9 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component Cellulase PF00150.13 EMR66752.1 - 0.0038 16.4 0.0 0.0062 15.7 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.20 EMR66753.1 - 2.3e-36 125.2 0.0 2.9e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR66753.1 - 1.2e-14 54.0 0.0 1.5e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMR66753.1 - 0.014 15.1 0.0 0.52 9.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family NACHT PF05729.7 EMR66754.1 - 4.2e-10 39.5 0.0 1.1e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMR66754.1 - 2.5e-06 27.5 0.0 3.4e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMR66754.1 - 4e-05 23.7 0.0 0.00016 21.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EMR66754.1 - 0.0017 17.3 0.1 0.23 10.4 0.3 2.3 1 1 1 2 2 2 2 KAP family P-loop domain AAA_10 PF12846.2 EMR66754.1 - 0.0032 16.9 0.0 1.5 8.1 0.0 2.5 3 0 0 3 3 3 2 AAA-like domain Porin_3 PF01459.17 EMR66755.1 - 3e-62 210.4 8.2 3.3e-62 210.2 5.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin Pex19 PF04614.7 EMR66756.1 - 6.8e-67 225.6 19.4 6.8e-67 225.6 13.5 1.6 1 1 0 1 1 1 1 Pex19 protein family Rrn6 PF10214.4 EMR66756.1 - 0.00065 17.9 2.2 0.0023 16.1 1.6 1.6 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Dam PF05869.6 EMR66756.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) DUF445 PF04286.7 EMR66756.1 - 0.096 12.1 1.9 1.2 8.5 1.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF445) TraG_N PF07916.6 EMR66756.1 - 0.34 9.2 2.2 0.51 8.7 1.5 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF1517 PF07466.6 EMR66757.1 - 0.018 14.0 1.6 0.024 13.6 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF1180 PF06679.7 EMR66757.1 - 0.12 12.2 1.5 0.23 11.3 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NLBH PF05211.7 EMR66757.1 - 0.21 10.7 0.0 0.31 10.2 0.0 1.1 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) Zn_clus PF00172.13 EMR66758.1 - 1.9e-08 34.0 8.3 3e-08 33.4 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Collagen PF01391.13 EMR66759.1 - 4.5e-05 22.9 16.9 4.5e-05 22.9 11.7 5.2 4 1 1 5 5 5 3 Collagen triple helix repeat (20 copies) Glyco_hydro_31 PF01055.21 EMR66760.1 - 1.3e-170 568.0 0.5 1.6e-170 567.7 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMR66760.1 - 4.5e-10 39.2 1.1 4.7e-09 35.9 0.3 2.8 2 0 0 2 2 2 1 Galactose mutarotase-like Ribosomal_L7Ae PF01248.21 EMR66761.1 - 2.3e-19 68.7 0.2 1.5e-18 66.0 0.1 2.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hid1 PF12722.2 EMR66761.1 - 5.1 4.6 5.9 6.6 4.2 4.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1761 PF08570.5 EMR66762.1 - 2.3e-21 76.1 1.8 2.6e-21 75.9 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) DUF1413 PF07205.6 EMR66763.1 - 0.048 13.2 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) Clc-like PF07062.7 EMR66764.1 - 0.098 11.9 0.5 0.5 9.5 0.1 2.1 1 1 1 2 2 2 0 Clc-like MFS_1 PF07690.11 EMR66766.1 - 1.1e-37 129.5 39.8 1.1e-37 129.5 27.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR66766.1 - 1.4e-10 40.3 16.2 1.4e-10 40.3 11.2 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter CDP-OH_P_transf PF01066.16 EMR66768.1 - 3.8e-17 62.4 1.1 3.8e-17 62.4 0.8 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase FixP_N PF14715.1 EMR66768.1 - 0.94 8.9 7.2 4 6.8 0.9 3.1 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF1690 PF07956.6 EMR66769.1 - 3.5e-36 124.2 3.0 4.2e-36 124.0 2.1 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF3708 PF12501.3 EMR66769.1 - 0.019 14.8 1.8 0.027 14.2 1.3 1.3 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter PAP_central PF04928.12 EMR66769.1 - 0.029 13.2 2.0 0.039 12.7 1.4 1.3 1 0 0 1 1 1 0 Poly(A) polymerase central domain Erp_C PF06780.6 EMR66769.1 - 0.029 14.2 0.6 0.039 13.8 0.4 1.2 1 0 0 1 1 1 0 Erp protein C-terminus Lectin_N PF03954.9 EMR66769.1 - 0.065 12.6 0.5 0.083 12.2 0.4 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Lzipper-MIP1 PF14389.1 EMR66769.1 - 0.092 12.8 11.2 0.11 12.6 2.1 2.6 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 FUSC PF04632.7 EMR66769.1 - 1.5 7.1 4.3 1.7 6.9 3.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Matrilin_ccoil PF10393.4 EMR66769.1 - 2.1 7.7 5.1 12 5.3 0.1 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Atg14 PF10186.4 EMR66769.1 - 3.7 6.3 8.8 4.6 6.0 6.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SSF PF00474.12 EMR66770.1 - 1e-07 31.0 32.4 1e-06 27.7 22.4 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family MDH PF02315.11 EMR66770.1 - 0.041 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit RRM_1 PF00076.17 EMR66771.1 - 1.3e-23 82.3 0.1 4.3e-11 42.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR66771.1 - 1.6e-16 59.9 0.3 1.3e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR66771.1 - 1.6e-09 37.4 0.7 0.0016 18.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EMR66771.1 - 0.0024 17.5 0.2 0.073 12.8 0.0 2.4 2 0 0 2 2 2 1 Limkain b1 TYW3 PF02676.9 EMR66772.1 - 6.5e-62 208.3 0.0 8.6e-62 207.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF2014 PF09427.5 EMR66773.1 - 2.3e-104 348.1 3.8 3.6e-104 347.5 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) Nitrate_red_del PF02613.10 EMR66773.1 - 0.029 14.2 0.2 0.068 13.0 0.1 1.6 1 0 0 1 1 1 0 Nitrate reductase delta subunit NDT80_PhoG PF05224.7 EMR66774.1 - 4.8e-33 114.7 0.0 1e-32 113.6 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_3 PF00933.16 EMR66775.1 - 7.3e-53 179.4 0.0 1e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 EMR66775.1 - 0.0028 17.6 0.0 0.0066 16.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMR66775.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR66775.1 - 0.021 14.9 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidohydro_4 PF13147.1 EMR66776.1 - 1.4e-13 51.5 1.3 8.5e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EMR66776.1 - 6.9e-06 25.9 0.0 0.0036 17.0 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EMR66776.1 - 9.4e-05 21.7 0.0 0.00019 20.7 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMR66776.1 - 0.00011 21.9 0.0 0.00031 20.4 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase SSB PF00436.20 EMR66777.1 - 3.7e-19 68.5 0.0 4.6e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family ADH_zinc_N PF00107.21 EMR66778.1 - 8e-09 35.1 0.0 1.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR66778.1 - 2e-08 33.9 0.0 3.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Nrf1_DNA-bind PF10491.4 EMR66778.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 EF-hand_6 PF13405.1 EMR66779.1 - 5.8e-11 41.3 0.0 0.00012 21.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EMR66779.1 - 1.6e-09 36.3 0.4 0.00014 20.9 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 EMR66779.1 - 8.8e-07 28.0 3.2 0.0033 16.6 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EMR66779.1 - 1.6e-06 28.1 0.0 2.1e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EMR66779.1 - 0.00013 21.5 0.0 0.41 10.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair DUF1183 PF06682.7 EMR66781.1 - 0.014 15.0 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Sugar_tr PF00083.19 EMR66782.1 - 3.2e-56 190.8 4.6 3.2e-56 190.8 3.2 1.9 1 1 1 2 2 2 2 Sugar (and other) transporter Ribosomal_L14 PF00238.14 EMR66783.1 - 1.8e-43 147.1 1.9 2e-43 147.0 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Glyco_hydro_28 PF00295.12 EMR66784.1 - 4e-35 121.3 3.3 7.1e-35 120.5 2.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Actin PF00022.14 EMR66785.1 - 7.1e-29 100.4 0.0 1.6e-19 69.6 0.0 2.8 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EMR66785.1 - 0.016 13.8 0.0 0.075 11.6 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein MFS_1 PF07690.11 EMR66786.1 - 1.3e-25 89.8 29.4 1.7e-25 89.4 14.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily RTA1 PF04479.8 EMR66788.1 - 2.7e-44 151.3 0.6 3.4e-44 150.9 0.4 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3593 PF12159.3 EMR66788.1 - 0.067 12.9 4.9 0.45 10.3 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3593) RTA1 PF04479.8 EMR66789.1 - 3.4e-43 147.7 0.4 4.8e-43 147.2 0.3 1.1 1 0 0 1 1 1 1 RTA1 like protein NfeD PF01957.13 EMR66789.1 - 0.089 12.9 0.2 0.089 12.9 0.1 2.6 2 2 2 4 4 4 0 NfeD-like C-terminal, partner-binding Fungal_trans PF04082.13 EMR66790.1 - 1.5e-22 79.7 0.0 3.6e-22 78.5 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain PRP1_N PF06424.7 EMR66790.1 - 0.026 14.8 0.0 0.063 13.6 0.0 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Sugar_tr PF00083.19 EMR66791.1 - 6.5e-106 354.6 25.1 7.9e-106 354.3 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR66791.1 - 1.1e-27 96.7 28.3 1.2e-20 73.5 4.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR66791.1 - 3.4e-05 22.4 27.3 4.4e-05 22.0 3.0 3.0 2 2 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EMR66791.1 - 0.00039 18.7 1.5 0.00039 18.7 1.0 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 EMR66791.1 - 0.016 15.2 1.3 0.11 12.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) IlvC PF01450.14 EMR66791.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain MFS_3 PF05977.8 EMR66791.1 - 0.41 8.7 7.1 0.068 11.2 0.2 2.4 2 1 1 3 3 3 0 Transmembrane secretion effector Catalase PF00199.14 EMR66792.1 - 1.1e-162 541.0 1.4 1.4e-162 540.7 1.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EMR66792.1 - 1.4e-19 69.7 0.1 2.5e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EMR66792.1 - 9.6e-13 47.8 0.0 2e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family TPP_enzyme_N PF02776.13 EMR66793.1 - 1.3e-39 135.3 1.0 7.1e-39 133.0 0.4 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EMR66793.1 - 3e-15 56.1 0.0 5.5e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMR66793.1 - 2.7e-14 53.1 0.0 5.6e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Alk_phosphatase PF00245.15 EMR66794.1 - 2.5e-76 257.0 0.0 2.9e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EMR66794.1 - 0.061 12.7 0.3 0.1 11.9 0.2 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily AAA_3 PF07726.6 EMR66794.1 - 0.086 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4451 PF14616.1 EMR66795.1 - 1.9e-29 101.9 0.1 3.4e-29 101.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Acetyltransf_3 PF13302.1 EMR66796.1 - 2.1e-32 112.2 0.0 2.7e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMR66796.1 - 0.00027 20.9 0.0 0.0027 17.6 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR66796.1 - 0.008 16.1 0.1 0.1 12.6 0.1 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EMR66796.1 - 0.084 12.7 0.0 0.68 9.8 0.0 2.1 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Skp1 PF01466.14 EMR66797.1 - 4.3e-39 132.3 1.0 4.3e-39 132.3 0.7 1.9 3 0 0 3 3 3 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EMR66797.1 - 1.4e-22 79.5 0.1 2.9e-22 78.5 0.1 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 EMR66797.1 - 0.032 14.2 0.5 0.074 13.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) GMC_oxred_N PF00732.14 EMR66798.1 - 6.5e-62 209.3 0.0 8.6e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR66798.1 - 1.4e-30 106.5 0.0 2.3e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EMR66798.1 - 0.00029 19.9 0.3 0.00042 19.3 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EMR66798.1 - 0.052 12.3 0.9 4.8 5.9 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EMR66798.1 - 0.19 10.7 0.1 0.33 10.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EMR66798.1 - 0.3 9.6 0.3 0.43 9.1 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Sugar_tr PF00083.19 EMR66799.1 - 3.8e-28 98.2 4.6 9.7e-23 80.4 3.8 3.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR66799.1 - 2.3e-09 36.4 23.3 1.1e-07 30.8 8.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinocilin PF15033.1 EMR66799.1 - 0.02 14.4 0.1 0.037 13.5 0.0 1.5 2 0 0 2 2 2 0 Kinocilin protein SNF2_N PF00176.18 EMR66800.1 - 1.6e-48 165.0 0.2 4.3e-48 163.6 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMR66800.1 - 4.3e-18 64.9 0.1 8.7e-16 57.5 0.1 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Prominin PF05478.6 EMR66800.1 - 0.05 11.1 0.3 0.082 10.4 0.2 1.2 1 0 0 1 1 1 0 Prominin MFS_1 PF07690.11 EMR66801.1 - 8.8e-14 50.9 34.7 1.3e-07 30.6 9.3 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EMR66801.1 - 2.1e-07 29.6 3.5 2.7e-05 22.7 1.0 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein ATG22 PF11700.3 EMR66801.1 - 1.1e-05 24.1 0.0 0.00019 20.0 0.0 2.5 1 1 0 2 2 2 1 Vacuole effluxer Atg22 like Zip PF02535.17 EMR66801.1 - 0.0053 15.8 0.0 0.17 10.8 0.4 2.5 1 1 1 2 2 2 1 ZIP Zinc transporter DUF4131 PF13567.1 EMR66801.1 - 0.47 9.8 8.6 0.73 9.2 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) HeLo PF14479.1 EMR66803.1 - 7.3e-27 94.5 1.9 9.6e-27 94.1 1.3 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation GRP PF07172.6 EMR66805.1 - 2.8e-06 27.7 1.6 3.9e-06 27.2 1.1 1.3 1 0 0 1 1 1 1 Glycine rich protein family DUF429 PF04250.8 EMR66805.1 - 0.015 14.5 0.3 0.024 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF429) U79_P34 PF03064.11 EMR66805.1 - 0.05 13.1 4.7 0.062 12.8 3.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 HemY_N PF07219.8 EMR66805.1 - 0.18 11.3 6.6 2 7.9 4.8 2.1 1 1 0 1 1 1 0 HemY protein N-terminus Tom5 PF10642.4 EMR66805.1 - 0.26 10.9 1.5 0.84 9.3 1.1 1.8 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Chorion_3 PF05387.6 EMR66805.1 - 0.73 9.2 3.2 0.97 8.8 2.2 1.1 1 0 0 1 1 1 0 Chorion family 3 OAD_gamma PF04277.8 EMR66805.1 - 0.78 10.1 3.3 0.46 10.8 0.6 1.8 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain FadA PF09403.5 EMR66805.1 - 1.9 8.5 6.8 0.45 10.5 0.6 2.1 2 0 0 2 2 2 0 Adhesion protein FadA Synaphin PF05835.7 EMR66805.1 - 2.2 8.4 8.1 2.1 8.5 0.8 2.1 2 0 0 2 2 2 0 Synaphin protein Serglycin PF04360.7 EMR66805.1 - 6.4 6.5 6.0 13 5.5 4.0 1.5 1 1 0 1 1 1 0 Serglycin GSH_synth_ATP PF03917.12 EMR66806.1 - 1e-96 323.8 0.0 4.7e-96 321.5 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EMR66806.1 - 4.1e-31 107.1 0.0 6.3e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Serglycin PF04360.7 EMR66807.1 - 0.085 12.5 3.9 0.16 11.6 2.7 1.4 1 0 0 1 1 1 0 Serglycin GATase_5 PF13507.1 EMR66809.1 - 9.8e-96 319.6 0.0 1.5e-95 319.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EMR66809.1 - 4.1e-43 147.0 0.0 1.1e-21 77.4 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EMR66809.1 - 1.5e-13 50.8 0.0 4.8e-13 49.1 0.0 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Ral PF11058.3 EMR66810.1 - 0.074 12.4 0.3 0.14 11.5 0.2 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral SET PF00856.23 EMR66812.1 - 3.1e-08 34.0 0.0 1.5e-07 31.8 0.0 2.2 1 0 0 1 1 1 1 SET domain Pyr_redox_2 PF07992.9 EMR66813.1 - 1.3e-05 25.1 0.0 4.3e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Arf PF00025.16 EMR66814.1 - 6.4e-59 198.0 0.2 1.8e-57 193.3 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EMR66814.1 - 1.8e-08 33.5 0.1 4.4e-08 32.2 0.1 1.6 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.17 EMR66814.1 - 3.4e-07 29.7 0.0 4.5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EMR66814.1 - 3.6e-06 26.3 0.0 4.3e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EMR66814.1 - 1.7e-05 24.1 0.0 2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EMR66814.1 - 6.3e-05 23.4 0.0 8.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EMR66814.1 - 0.00044 19.7 0.0 0.00054 19.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EMR66814.1 - 0.029 13.1 0.1 0.11 11.2 0.0 1.8 1 1 0 1 1 1 0 ArgK protein DUF3986 PF13143.1 EMR66814.1 - 0.062 13.7 0.2 0.21 12.0 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) PTCB-BRCT PF12738.2 EMR66815.1 - 1.4e-31 108.1 0.0 2.8e-18 65.5 0.0 4.2 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 EMR66815.1 - 1.9e-26 91.9 0.0 1.1e-11 44.7 0.0 4.7 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain Podoplanin PF05808.6 EMR66815.1 - 9.7 5.7 15.6 0.23 10.9 2.3 2.8 1 1 1 2 2 2 0 Podoplanin CybS PF05328.7 EMR66816.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 CybS DUF1996 PF09362.5 EMR66817.1 - 4.8e-80 268.5 3.5 4.8e-80 268.5 2.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) WD40 PF00400.27 EMR66818.1 - 0.0033 17.2 0.2 0.0063 16.3 0.1 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat PNRC PF15365.1 EMR66818.1 - 2.4 8.2 7.2 0.31 11.0 1.1 2.1 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator CN_hydrolase PF00795.17 EMR66820.1 - 3.3e-35 121.1 0.0 4.4e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TPR_11 PF13414.1 EMR66821.1 - 1.2e-35 121.0 15.1 1.3e-15 56.7 0.3 5.7 4 1 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 EMR66821.1 - 4e-35 117.9 8.0 3.1e-08 32.8 0.1 8.2 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 EMR66821.1 - 1.8e-30 102.3 10.3 3.9e-06 26.3 0.0 8.4 6 1 2 8 8 8 5 Tetratricopeptide repeat DnaJ PF00226.26 EMR66821.1 - 1.9e-28 97.9 5.9 7.2e-28 96.1 3.1 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.1 EMR66821.1 - 2.7e-20 72.4 10.0 4.6e-08 33.2 0.0 5.7 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMR66821.1 - 5.2e-20 71.5 18.7 1.3e-07 32.0 0.0 6.0 7 1 1 8 8 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMR66821.1 - 1.3e-16 59.0 0.1 0.00013 21.4 0.0 5.8 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMR66821.1 - 2.7e-16 58.5 13.1 0.00011 22.4 0.0 7.8 4 3 4 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 EMR66821.1 - 2.4e-14 53.0 8.1 8.9e-06 25.5 0.0 5.2 3 1 2 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMR66821.1 - 2.4e-14 52.2 10.8 0.0081 16.2 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.1 EMR66821.1 - 8.9e-13 47.9 8.1 0.0077 16.0 0.6 5.0 3 1 1 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EMR66821.1 - 1.4e-12 47.6 5.2 2.9e-05 24.0 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EMR66821.1 - 5.2e-09 35.2 4.7 0.057 13.2 0.0 6.4 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMR66821.1 - 6.2e-09 35.7 7.7 0.04 14.3 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 EMR66821.1 - 6.2e-08 32.0 8.3 0.037 13.0 0.0 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMR66821.1 - 2e-05 24.3 3.7 4.8 7.1 0.0 4.6 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 EMR66821.1 - 0.00044 20.4 0.6 6.6 7.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.12 EMR66821.1 - 0.0045 17.3 12.4 0.13 12.5 0.1 4.8 4 1 0 4 4 4 1 Bacterial transcriptional activator domain TPR_20 PF14561.1 EMR66821.1 - 0.0051 16.9 10.6 1 9.5 0.0 4.8 3 3 3 6 6 6 1 Tetratricopeptide repeat Coatomer_E PF04733.9 EMR66821.1 - 0.0056 15.8 0.1 2.3 7.3 0.0 3.2 3 0 0 3 3 3 1 Coatomer epsilon subunit Alkyl_sulf_dimr PF14863.1 EMR66821.1 - 0.0057 16.9 1.1 0.63 10.2 0.0 3.5 2 1 1 3 3 3 1 Alkyl sulfatase dimerisation TPR_21 PF09976.4 EMR66821.1 - 0.0081 16.1 10.7 0.13 12.2 0.2 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat NatB_MDM20 PF09797.4 EMR66821.1 - 0.02 13.6 0.3 0.045 12.4 0.0 1.7 2 0 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF3856 PF12968.2 EMR66821.1 - 0.028 14.2 1.4 36 4.1 0.0 4.9 4 2 2 6 6 6 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.1 EMR66821.1 - 3.3 7.7 14.8 27 4.8 0.0 6.0 6 1 0 6 6 6 0 Tetratricopeptide repeat IER PF05760.7 EMR66822.1 - 0.064 13.1 2.5 0.063 13.1 1.7 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Ribosomal_L37 PF08561.5 EMR66822.1 - 0.47 10.0 2.8 0.66 9.5 1.8 1.4 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L37 DUF4203 PF13886.1 EMR66823.1 - 8.6e-31 107.0 25.3 1.2e-30 106.6 17.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Aldedh PF00171.17 EMR66824.1 - 2.9e-120 401.7 0.3 1.1e-85 287.7 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family MFS_1 PF07690.11 EMR66825.1 - 4.9e-14 51.8 14.4 4.9e-14 51.8 10.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR66825.1 - 1.4e-09 37.1 11.6 2.6e-09 36.2 8.0 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EMR66825.1 - 0.016 13.4 7.1 0.6 8.2 2.9 2.0 1 1 1 2 2 2 0 Fungal trichothecene efflux pump (TRI12) YrhC PF14143.1 EMR66825.1 - 0.32 10.9 2.0 29 4.6 0.0 2.9 2 1 0 2 2 2 0 YrhC-like protein DUF1211 PF06736.6 EMR66825.1 - 1.1 9.4 7.7 11 6.2 2.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1211) Sulfotransfer_3 PF13469.1 EMR66826.1 - 0.016 16.1 0.2 0.036 14.9 0.1 1.8 1 1 0 1 1 1 0 Sulfotransferase family Zn_clus PF00172.13 EMR66827.1 - 0.012 15.4 0.3 0.023 14.5 0.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MIP-T3 PF10243.4 EMR66828.1 - 0.08 11.4 8.7 0.14 10.6 6.0 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 adh_short PF00106.20 EMR66829.1 - 5.6e-09 36.1 0.0 4.8e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR66829.1 - 0.0012 18.5 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 KR domain p450 PF00067.17 EMR66830.1 - 4.7e-44 150.6 0.0 5.9e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mpv17_PMP22 PF04117.7 EMR66831.1 - 9.3e-21 73.2 0.1 1.9e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family GtrA PF04138.9 EMR66831.1 - 0.049 13.5 3.1 0.11 12.4 0.0 2.2 2 1 0 2 2 2 0 GtrA-like protein SURF4 PF02077.10 EMR66833.1 - 4.7e-97 324.5 6.1 5.3e-97 324.3 4.2 1.0 1 0 0 1 1 1 1 SURF4 family Peptidase_A24 PF01478.13 EMR66833.1 - 1.6 8.8 13.0 0.89 9.7 0.5 2.7 2 1 0 2 2 2 0 Type IV leader peptidase family Wzy_C PF04932.10 EMR66833.1 - 7.3 6.3 10.5 0.73 9.6 2.2 2.2 2 0 0 2 2 2 0 O-Antigen ligase GMC_oxred_N PF00732.14 EMR66835.1 - 7.8e-48 163.1 0.0 1.1e-47 162.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR66835.1 - 1.6e-42 145.2 0.0 3e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMR66835.1 - 3.9e-06 25.9 0.2 0.0013 17.7 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR66835.1 - 4e-05 22.7 0.5 0.00023 20.2 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR66835.1 - 0.00075 19.4 0.1 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR66835.1 - 0.0032 16.4 0.8 0.0056 15.6 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMR66835.1 - 0.0044 17.0 0.5 0.012 15.5 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EMR66835.1 - 0.012 14.2 0.5 0.021 13.4 0.4 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EMR66835.1 - 0.012 15.6 0.1 0.036 14.1 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR66835.1 - 0.055 13.2 0.4 0.15 11.8 0.3 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EMR66835.1 - 0.059 12.4 0.3 1.4 7.8 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Sugar_tr PF00083.19 EMR66836.1 - 2.5e-80 270.2 15.5 2.9e-80 270.0 10.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR66836.1 - 3.9e-30 104.7 18.1 5.7e-30 104.2 12.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EMR66836.1 - 4e-07 28.7 11.0 2.1e-06 26.4 1.0 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EMR66836.1 - 2.8e-06 25.8 2.9 0.00021 19.6 0.4 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.11 EMR66836.1 - 0.0049 16.3 1.1 0.017 14.6 0.8 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 OATP PF03137.15 EMR66836.1 - 0.023 12.7 3.2 0.041 11.9 2.2 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.13 EMR66837.1 - 1.2e-06 28.3 9.7 2.5e-06 27.2 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bul1_N PF04425.7 EMR66838.1 - 3.2e-06 25.9 0.3 0.0019 16.8 0.0 3.1 2 1 1 3 3 3 2 Bul1 N terminus Bul1_C PF04426.7 EMR66838.1 - 0.00014 21.1 0.0 0.00052 19.3 0.0 1.8 2 0 0 2 2 2 1 Bul1 C terminus ABC2_membrane PF01061.19 EMR66839.1 - 1.7e-91 305.0 53.9 5.5e-47 159.6 11.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EMR66839.1 - 1.2e-33 116.3 0.4 1.7e-15 57.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 EMR66839.1 - 3.7e-32 110.0 0.3 5.8e-26 90.1 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EMR66839.1 - 1.2e-07 31.0 26.5 0.00055 19.0 6.3 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EMR66839.1 - 2.3e-06 27.8 0.1 0.0043 17.0 0.1 3.3 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 EMR66839.1 - 3.9e-06 26.4 0.1 0.00058 19.3 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EMR66839.1 - 1.2e-05 24.8 0.0 0.44 9.9 0.0 3.6 3 1 0 3 3 3 2 AAA domain ABC_trans_N PF14510.1 EMR66839.1 - 1.4e-05 25.0 0.0 3.6e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 EMR66839.1 - 3.2e-05 23.1 0.0 0.00071 18.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMR66839.1 - 3.8e-05 23.1 0.3 0.19 11.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.1 EMR66839.1 - 8.2e-05 22.6 0.4 0.0054 16.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EMR66839.1 - 0.00019 21.2 0.1 0.036 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EMR66839.1 - 0.00028 20.8 0.0 0.076 12.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMR66839.1 - 0.00028 21.0 0.1 0.38 10.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMR66839.1 - 0.00041 20.3 1.3 0.084 12.8 0.5 2.7 2 1 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EMR66839.1 - 0.00045 19.7 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_18 PF13238.1 EMR66839.1 - 0.00058 20.1 0.0 0.017 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EMR66839.1 - 0.0008 18.6 0.5 0.056 12.6 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EMR66839.1 - 0.0021 18.8 0.0 0.12 13.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMR66839.1 - 0.0085 15.7 0.2 0.3 10.7 0.2 2.4 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 EMR66839.1 - 0.0096 15.5 0.3 0.089 12.4 0.1 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 INCENP_ARK-bind PF03941.10 EMR66839.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region AAA_24 PF13479.1 EMR66839.1 - 0.016 14.7 0.2 0.24 10.9 0.2 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EMR66839.1 - 0.017 13.9 0.1 2.4 6.9 0.1 2.6 3 0 0 3 3 3 0 NB-ARC domain ArgK PF03308.11 EMR66839.1 - 0.027 13.2 0.0 3.1 6.5 0.0 2.7 3 0 0 3 3 3 0 ArgK protein T2SE PF00437.15 EMR66839.1 - 0.073 11.9 0.4 6.2 5.6 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein APS_kinase PF01583.15 EMR66839.1 - 0.096 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP-synt_ab PF00006.20 EMR66839.1 - 0.096 12.1 0.0 0.92 8.9 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.13 EMR66839.1 - 0.12 11.4 0.4 0.37 9.7 0.1 1.9 2 0 0 2 2 2 0 Septin Miro PF08477.8 EMR66839.1 - 0.14 12.6 0.1 3.2 8.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 EMR66839.1 - 0.21 11.0 0.8 0.45 9.9 0.3 1.7 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation GBP PF02263.14 EMR66839.1 - 0.23 10.4 0.0 0.42 9.6 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_10 PF12846.2 EMR66839.1 - 0.27 10.6 1.7 7.4 5.9 0.2 2.5 2 0 0 2 2 2 0 AAA-like domain OAD_gamma PF04277.8 EMR66839.1 - 0.32 11.3 1.8 0.39 11.1 0.1 2.0 2 0 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain AAA_15 PF13175.1 EMR66839.1 - 0.51 9.3 0.0 21 4.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Clat_adaptor_s PF01217.15 EMR66840.1 - 3.2e-15 56.1 1.4 2e-14 53.4 0.9 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Sua5_yciO_yrdC PF01300.13 EMR66841.1 - 3.5e-54 182.7 0.0 5.9e-54 182.0 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EMR66841.1 - 3.4e-26 91.7 0.0 1.3e-25 89.8 0.0 1.9 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding MCM PF00493.18 EMR66842.1 - 2.9e-139 463.5 0.0 3.6e-139 463.1 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family AAA_5 PF07728.9 EMR66842.1 - 4.4e-07 29.7 0.0 2.6e-06 27.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EMR66842.1 - 2.1e-06 27.0 0.0 0.00025 20.2 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EMR66842.1 - 0.00031 20.3 0.0 0.0018 17.8 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EMR66842.1 - 0.014 14.8 0.2 1.9 7.8 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_32 PF13654.1 EMR66842.1 - 0.04 12.5 0.9 0.088 11.4 0.6 1.5 1 0 0 1 1 1 0 AAA domain PWI PF01480.12 EMR66843.1 - 5.5e-30 103.3 0.0 1.1e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 PWI domain Shisa PF13908.1 EMR66843.1 - 0.08 13.1 1.3 0.16 12.1 0.9 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator IBR PF01485.16 EMR66844.1 - 9.3e-09 35.0 36.3 2.7e-06 27.1 8.7 3.5 3 0 0 3 3 3 2 IBR domain COG4 PF08318.7 EMR66845.1 - 1.4e-72 244.2 0.0 3.6e-56 190.3 0.0 3.0 1 1 1 2 2 2 2 COG4 transport protein Glyco_hydro_2_N PF02837.13 EMR66846.1 - 1.4e-15 57.2 0.0 2.6e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EMR66846.1 - 4.8e-15 55.2 0.0 2.3e-14 53.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EMR66846.1 - 3.6e-10 40.2 0.0 1.4e-09 38.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 Abhydrolase_3 PF07859.8 EMR66847.1 - 2e-13 50.3 0.0 2.6e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Zip PF02535.17 EMR66848.1 - 2.9e-59 200.6 5.4 8.2e-59 199.1 3.7 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter FAA_hydrolase PF01557.13 EMR66849.1 - 3.1e-51 173.9 0.0 3.7e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ZU5 PF00791.15 EMR66849.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 ZU5 domain TBCA PF02970.11 EMR66850.1 - 1.2e-17 63.7 10.2 2.4e-17 62.7 7.1 1.4 1 1 0 1 1 1 1 Tubulin binding cofactor A Syntaxin PF00804.20 EMR66850.1 - 0.034 14.2 2.1 0.043 13.9 1.4 1.3 1 0 0 1 1 1 0 Syntaxin Herpes_UL14 PF03580.9 EMR66850.1 - 0.076 12.8 2.6 0.099 12.4 1.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL14-like protein TMF_DNA_bd PF12329.3 EMR66850.1 - 2.2 8.1 14.2 2.9 7.7 7.0 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding PTR2 PF00854.16 EMR66851.1 - 1.1e-40 139.5 13.6 4e-39 134.4 9.4 2.6 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 EMR66851.1 - 1.6e-05 23.7 28.8 0.00023 20.0 3.4 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Glyco_hydro_18 PF00704.23 EMR66852.1 - 1.2e-94 317.6 8.2 1.4e-94 317.4 5.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 COX17 PF05051.8 EMR66853.1 - 5.3e-20 71.1 4.9 6.8e-20 70.8 3.4 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.7 EMR66853.1 - 0.11 12.3 2.8 0.3 10.9 1.9 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Alg6_Alg8 PF03155.10 EMR66854.1 - 4.5e-128 428.0 25.2 1.1e-79 268.4 7.5 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Cap_synth_GfcB PF11102.3 EMR66855.1 - 0.0018 17.8 0.2 0.0025 17.3 0.1 1.3 1 0 0 1 1 1 1 Group 4 capsule polysaccharide formation lipoprotein gfcB PXA PF02194.10 EMR66855.1 - 0.25 10.9 1.2 0.34 10.4 0.8 1.2 1 0 0 1 1 1 0 PXA domain DDE_1 PF03184.14 EMR66856.1 - 1.2e-29 103.0 0.0 2.2e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EMR66856.1 - 7e-10 38.2 0.7 1.6e-09 37.1 0.2 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EMR66856.1 - 8.4e-05 22.3 0.4 0.00029 20.5 0.1 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CUE PF02845.11 EMR66857.1 - 6.8e-12 44.6 0.0 1.1e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain TSSC4 PF15264.1 EMR66857.1 - 0.053 13.9 1.9 0.092 13.1 1.3 1.5 1 1 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 TMEM171 PF15471.1 EMR66857.1 - 0.58 8.8 4.0 1.1 8.0 2.8 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Conotoxin PF02950.12 EMR66857.1 - 0.72 10.7 2.6 2.1 9.1 0.0 2.6 2 1 1 3 3 3 0 Conotoxin FAM177 PF14774.1 EMR66858.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 FAM177 family DEAD PF00270.24 EMR66859.1 - 2.9e-40 137.5 0.0 1.1e-39 135.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR66859.1 - 5.5e-23 80.6 0.2 1.4e-22 79.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EMR66859.1 - 0.02 14.8 0.0 0.062 13.2 0.0 1.7 2 0 0 2 2 2 0 Helicase C-terminal domain ResIII PF04851.10 EMR66859.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit FAD_binding_4 PF01565.18 EMR66860.1 - 6e-14 51.7 2.6 6e-14 51.7 1.8 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EMR66860.1 - 0.0014 17.7 1.8 0.0021 17.1 0.5 1.8 2 0 0 2 2 2 1 Thi4 family DUF4160 PF13711.1 EMR66860.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) WD40 PF00400.27 EMR66861.1 - 2.4e-22 77.9 3.9 2.7e-07 30.1 0.4 5.6 6 0 0 6 6 6 5 WD domain, G-beta repeat SMC_N PF02463.14 EMR66862.1 - 3e-35 121.4 12.9 3e-35 121.4 8.9 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EMR66862.1 - 1.2e-21 76.8 1.3 6.1e-21 74.6 0.1 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EMR66862.1 - 1.4e-06 28.5 0.6 3.5e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Reo_sigmaC PF04582.7 EMR66862.1 - 3.3e-05 23.2 34.1 9.5e-05 21.7 0.3 6.8 3 2 4 8 8 8 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 EMR66862.1 - 6e-05 22.4 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 EMR66862.1 - 0.0029 16.8 8.5 0.0029 16.8 5.9 8.0 2 2 5 8 8 8 2 Growth-arrest specific micro-tubule binding MscS_porin PF12795.2 EMR66862.1 - 0.0038 16.5 24.8 0.0038 16.5 17.2 6.2 4 3 2 6 6 6 2 Mechanosensitive ion channel porin domain COG2 PF06148.6 EMR66862.1 - 0.0081 16.0 2.3 0.0081 16.0 1.6 9.5 5 2 3 8 8 8 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF4250 PF14056.1 EMR66862.1 - 0.016 14.8 2.6 9.6 6.0 0.0 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) GFA PF04828.9 EMR66863.1 - 1.9e-19 69.3 2.9 1.1e-08 34.8 0.1 3.0 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.8 EMR66863.1 - 0.11 12.0 6.9 0.27 10.7 1.5 2.5 2 0 0 2 2 2 0 CSL zinc finger Nudix_N_2 PF14803.1 EMR66863.1 - 1.5 8.6 11.8 9.5 6.0 0.1 4.3 4 0 0 4 4 4 0 Nudix N-terminal 4HBT_2 PF13279.1 EMR66864.1 - 0.0049 17.3 0.0 0.0064 16.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Tyrosinase PF00264.15 EMR66865.1 - 8.3e-31 107.8 0.0 1.4e-30 107.1 0.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Thioredoxin PF00085.15 EMR66866.1 - 2.4e-63 210.3 0.0 5.1e-31 106.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EMR66866.1 - 2.2e-23 82.6 6.1 2.7e-23 82.4 0.8 3.0 4 0 0 4 4 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EMR66866.1 - 2.6e-19 69.4 0.2 6.1e-09 36.0 0.0 3.1 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMR66866.1 - 3.6e-14 52.5 0.0 2.5e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EMR66866.1 - 3.2e-13 49.6 0.0 1e-05 25.5 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 EMR66866.1 - 2.1e-09 37.1 0.1 0.00085 19.0 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EMR66866.1 - 3e-07 30.0 0.3 0.00089 18.8 0.0 2.3 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.8 EMR66866.1 - 8.6e-06 25.7 0.7 4.8e-05 23.2 0.0 2.5 3 1 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 EMR66866.1 - 1.1e-05 25.5 3.1 0.16 12.0 0.1 4.3 3 2 2 5 5 5 2 Thioredoxin Thioredoxin_3 PF13192.1 EMR66866.1 - 2.3e-05 24.1 0.0 0.066 13.0 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_9 PF14595.1 EMR66866.1 - 2.8e-05 23.6 0.0 0.088 12.3 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin HyaE PF07449.6 EMR66866.1 - 0.0012 18.7 0.0 0.059 13.2 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 EMR66866.1 - 0.0029 17.5 0.1 4.9 7.2 0.1 2.9 2 1 0 2 2 2 2 Glutaredoxin DSBA PF01323.15 EMR66866.1 - 0.0047 16.5 3.4 5.2 6.5 0.6 3.3 2 1 1 3 3 3 2 DSBA-like thioredoxin domain Mu-like_Com PF10122.4 EMR66866.1 - 0.28 10.2 1.0 6.2 5.9 0.1 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com GTP_EFTU PF00009.22 EMR66867.1 - 6.1e-60 201.8 0.3 8e-60 201.4 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMR66867.1 - 1e-26 92.9 0.0 7.3e-26 90.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMR66867.1 - 2.6e-17 62.7 2.2 2.6e-17 62.7 1.5 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMR66867.1 - 7.3e-06 25.9 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EMR66867.1 - 0.00065 19.2 0.3 0.0022 17.5 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EMR66867.1 - 0.001 19.5 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EMR66867.1 - 0.068 12.6 0.2 8 5.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EMR66867.1 - 0.087 11.9 0.1 0.31 10.1 0.1 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S14 PF00253.16 EMR66868.1 - 5.1e-17 61.0 3.0 8.1e-17 60.3 2.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EMR66868.1 - 0.017 14.8 0.2 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Herpes_gE PF02480.11 EMR66869.1 - 0.074 11.3 0.0 0.12 10.6 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E ATP_transf PF09830.4 EMR66870.1 - 9.8e-20 70.1 0.0 1.9e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 EMR66870.1 - 0.02 15.3 0.2 0.036 14.5 0.1 1.4 1 0 0 1 1 1 0 HIT domain Neurochondrin PF05536.6 EMR66871.1 - 1.8e-82 277.4 0.0 2.4e-82 277.0 0.0 1.1 1 0 0 1 1 1 1 Neurochondrin DUF4551 PF15087.1 EMR66872.1 - 1.5 7.1 4.5 1.9 6.7 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Shisa PF13908.1 EMR66873.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DNA_pol_A PF00476.15 EMR66874.1 - 2.5e-98 329.2 0.0 3.4e-98 328.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A DUF3405 PF11885.3 EMR66875.1 - 7.1e-155 516.0 0.0 2.7e-123 411.8 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) PRKCSH PF07915.8 EMR66876.1 - 3.2e-18 66.3 0.5 1.7e-17 63.9 0.0 2.4 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EMR66876.1 - 0.00052 19.5 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein MFS_1 PF07690.11 EMR66878.1 - 3.4e-06 26.0 20.2 0.0078 14.9 14.8 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR66878.1 - 6.6e-06 24.6 2.7 6.6e-06 24.6 1.9 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Cu-oxidase_2 PF07731.9 EMR66879.1 - 3.5e-37 127.0 1.9 4.1e-37 126.7 0.2 2.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EMR66879.1 - 4.4e-31 107.9 0.0 8.5e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase TFIID-18kDa PF02269.11 EMR66880.1 - 4.1e-17 61.7 0.0 6.7e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EMR66880.1 - 0.027 14.1 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TAF PF02969.12 EMR66880.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EMR66880.1 - 0.077 13.0 0.0 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMR66880.1 - 0.082 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF3720 PF12517.3 EMR66880.1 - 0.32 11.6 6.5 0.5 11.0 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) Tcp11 PF05794.8 EMR66881.1 - 1.6e-67 228.1 0.0 1.4e-59 202.0 0.0 2.1 2 0 0 2 2 2 2 T-complex protein 11 p450 PF00067.17 EMR66882.1 - 1.9e-59 201.3 0.0 2.5e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tfb4 PF03850.9 EMR66883.1 - 1.8e-88 296.4 0.0 2.3e-88 296.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 Atrophin-1 PF03154.10 EMR66883.1 - 0.33 9.0 8.0 0.47 8.5 5.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family Actin PF00022.14 EMR66884.1 - 1.3e-87 293.7 0.0 2.9e-87 292.6 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMR66884.1 - 0.04 12.5 0.1 2.4 6.6 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.13 EMR66885.1 - 1.4e-36 125.7 2.3 2.3e-21 75.8 0.0 2.3 2 0 0 2 2 2 2 Asparaginase Phage_cap_P2 PF05125.7 EMR66886.1 - 0.037 12.9 0.1 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Phage major capsid protein, P2 family Glyco_hydro_88 PF07470.8 EMR66887.1 - 1.8e-63 214.6 13.1 2.1e-63 214.4 9.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 adh_short PF00106.20 EMR66888.1 - 7.7e-11 42.1 5.9 2.9e-09 37.0 0.0 3.3 3 1 1 4 4 4 2 short chain dehydrogenase KR PF08659.5 EMR66888.1 - 8.1e-05 22.3 0.3 0.015 14.9 0.0 2.6 3 0 0 3 3 3 2 KR domain BRF1 PF07741.8 EMR66888.1 - 0.024 14.8 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain XRN_N PF03159.13 EMR66888.1 - 0.048 13.0 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus TraC PF07820.7 EMR66888.1 - 0.069 13.3 1.1 0.14 12.4 0.4 1.7 2 0 0 2 2 2 0 TraC-like protein ERF PF04404.7 EMR66888.1 - 0.14 11.6 6.0 0.26 10.8 4.2 1.3 1 0 0 1 1 1 0 ERF superfamily CcmD PF04995.9 EMR66888.1 - 0.76 9.5 3.1 1.5 8.6 2.1 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) TPR_12 PF13424.1 EMR66889.1 - 3.3e-22 78.2 17.5 1.1e-08 34.9 0.6 5.3 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 EMR66889.1 - 2.5e-13 49.4 17.2 0.03 14.2 1.2 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMR66889.1 - 3.8e-10 39.2 10.4 4.1e-06 26.3 1.4 4.5 3 1 1 4 4 4 3 TPR repeat NB-ARC PF00931.17 EMR66889.1 - 4.8e-10 38.7 0.0 3.2e-06 26.2 0.0 2.1 1 1 1 2 2 2 2 NB-ARC domain TPR_7 PF13176.1 EMR66889.1 - 1.3e-07 30.8 6.7 0.17 11.7 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMR66889.1 - 2.3e-06 27.7 13.5 0.3 11.8 0.0 6.3 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 EMR66889.1 - 2.7e-06 27.2 3.1 0.39 11.2 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMR66889.1 - 8.4e-06 25.1 12.9 0.0013 18.2 0.7 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMR66889.1 - 1.4e-05 24.6 11.8 0.28 11.2 0.9 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR66889.1 - 1.5e-05 25.2 2.9 0.62 10.4 0.1 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMR66889.1 - 4.6e-05 22.9 8.7 1.4 8.8 0.4 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMR66889.1 - 5e-05 23.1 1.1 6.2 7.2 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.15 EMR66889.1 - 0.0019 18.0 0.1 0.28 11.2 0.0 3.4 3 0 0 3 3 3 1 PPR repeat TPR_16 PF13432.1 EMR66889.1 - 0.0025 18.4 14.1 0.039 14.6 0.1 5.1 4 1 1 5 5 4 1 Tetratricopeptide repeat PPR_3 PF13812.1 EMR66889.1 - 0.0032 17.6 0.3 5.9 7.4 0.1 3.0 2 0 0 2 2 2 2 Pentatricopeptide repeat domain TPR_6 PF13174.1 EMR66889.1 - 0.068 13.6 7.3 31 5.3 0.6 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat NPFF PF15085.1 EMR66890.1 - 0.013 15.8 0.1 0.051 13.8 0.0 2.0 2 0 0 2 2 2 0 Neuropeptide FF BUD22 PF09073.5 EMR66890.1 - 9.3 5.2 7.3 11 4.9 4.7 1.4 1 1 0 1 1 1 0 BUD22 Ank_2 PF12796.2 EMR66892.1 - 3.2e-50 168.3 0.0 3.7e-16 59.2 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMR66892.1 - 2.1e-36 121.9 0.2 2.1e-08 33.5 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat zf-DHHC PF01529.15 EMR66892.1 - 1e-35 122.7 7.9 2.2e-35 121.6 5.5 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_5 PF13857.1 EMR66892.1 - 1.7e-28 97.9 3.7 5.2e-08 32.8 0.0 5.3 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR66892.1 - 3e-27 94.4 5.0 8.9e-09 35.6 0.0 4.9 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR66892.1 - 4.4e-24 82.1 1.5 8.1e-07 28.6 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat GtrA PF04138.9 EMR66892.1 - 3.1 7.7 13.2 0.067 13.1 3.4 2.4 3 0 0 3 3 3 0 GtrA-like protein MtrB PF05440.7 EMR66893.1 - 0.062 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B PcfK PF14058.1 EMR66894.1 - 0.032 14.3 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 PcfK-like protein LMP PF04778.7 EMR66894.1 - 0.034 13.9 0.6 0.04 13.6 0.4 1.2 1 0 0 1 1 1 0 LMP repeated region Prominin PF05478.6 EMR66895.1 - 0.0022 15.6 1.4 0.0029 15.2 1.0 1.1 1 0 0 1 1 1 1 Prominin BLOC1_2 PF10046.4 EMR66895.1 - 0.0066 16.5 0.5 0.019 15.0 0.0 2.0 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 EMR66895.1 - 0.031 14.5 3.9 0.059 13.6 0.1 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MitMem_reg PF13012.1 EMR66895.1 - 0.051 13.6 0.5 0.19 11.8 0.0 2.1 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function ERCC4 PF02732.10 EMR66897.1 - 4.1e-22 78.4 0.0 7.5e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain Herpes_UL25 PF01499.11 EMR66897.1 - 0.0096 14.2 1.0 0.01 14.1 0.7 1.2 1 0 0 1 1 1 1 Herpesvirus UL25 family Ycf1 PF05758.7 EMR66897.1 - 0.034 11.8 5.9 0.048 11.3 4.1 1.1 1 0 0 1 1 1 0 Ycf1 SR-25 PF10500.4 EMR66897.1 - 0.19 11.1 30.2 0.051 13.0 15.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cellulose_synt PF03552.9 EMR66897.1 - 0.38 8.9 4.3 0.51 8.5 3.0 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF3530 PF12048.3 EMR66897.1 - 2.2 7.2 13.7 0.32 9.9 6.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) RR_TM4-6 PF06459.7 EMR66897.1 - 5.2 6.8 12.6 8.3 6.2 8.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tho2 PF11262.3 EMR66897.1 - 7.1 5.5 11.7 12 4.8 8.1 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 V_ATPase_I PF01496.14 EMR66897.1 - 8.2 4.1 6.4 11 3.7 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAD_binding_4 PF01565.18 EMR66899.1 - 6.1e-28 97.0 0.3 2.2e-27 95.2 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EMR66899.1 - 0.0053 16.6 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Sugar_tr PF00083.19 EMR66900.1 - 4.3e-34 117.8 26.6 9.9e-19 67.2 6.8 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR66900.1 - 3e-24 85.4 41.5 3.2e-14 52.4 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR66900.1 - 1.8e-07 29.9 22.7 1.4e-05 23.6 3.2 2.6 1 1 0 2 2 2 2 MFS/sugar transport protein DUF2231 PF09990.4 EMR66900.1 - 0.12 12.7 7.5 1 9.7 4.2 2.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Peptidase_M24 PF00557.19 EMR66901.1 - 3.3e-37 128.0 0.0 5.5e-24 84.9 0.0 2.3 2 0 0 2 2 2 2 Metallopeptidase family M24 Creatinase_N PF01321.13 EMR66901.1 - 0.00023 21.6 0.0 0.00045 20.7 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain His_Phos_1 PF00300.17 EMR66902.1 - 1.4e-16 60.9 0.0 2.9e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CP12 PF02672.10 EMR66903.1 - 0.014 15.8 1.0 0.014 15.8 0.7 2.2 2 0 0 2 2 2 0 CP12 domain DUF572 PF04502.8 EMR66903.1 - 4.6 6.3 7.9 8.9 5.4 5.4 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF572) PBP1_TM PF14812.1 EMR66903.1 - 7.5 6.9 11.4 5.9 7.2 1.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAD_binding_2 PF00890.19 EMR66904.1 - 4.9e-62 210.1 6.8 5.8e-62 209.8 4.7 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR66904.1 - 5.3e-09 35.4 3.5 2.5e-08 33.2 2.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR66904.1 - 9.3e-08 31.9 2.4 1.7e-07 31.1 1.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMR66904.1 - 9.2e-07 28.2 1.6 1.4e-06 27.6 1.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR66904.1 - 1.6e-06 28.1 0.9 1.1e-05 25.4 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR66904.1 - 3e-05 24.3 0.2 0.0026 18.1 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR66904.1 - 3e-05 23.2 1.1 5.6e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EMR66904.1 - 5.3e-05 22.4 0.1 8.5e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EMR66904.1 - 8.3e-05 21.6 0.9 8.3e-05 21.6 0.6 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EMR66904.1 - 9.5e-05 22.5 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR66904.1 - 0.00048 18.7 0.5 0.00048 18.7 0.3 2.7 3 1 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.7 EMR66904.1 - 0.047 12.6 0.7 0.072 11.9 0.3 1.6 1 1 1 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EMR66904.1 - 0.054 13.1 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Strep_67kDa_ant PF06100.6 EMR66904.1 - 0.062 11.6 0.1 0.083 11.2 0.1 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_7 PF13241.1 EMR66904.1 - 0.072 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.12 EMR66906.1 - 1.8e-104 347.8 0.0 2.2e-104 347.5 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EMR66906.1 - 5.7e-10 38.6 0.2 2e-08 33.5 0.2 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMR66906.1 - 5.2e-06 25.6 0.3 1.5e-05 24.1 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMR66906.1 - 1.2e-05 25.2 0.4 3.2e-05 23.8 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMR66906.1 - 2.7e-05 24.0 0.0 8.2e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EMR66906.1 - 7.1e-05 21.8 2.4 0.0028 16.5 0.1 2.9 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 EMR66906.1 - 0.00021 21.3 0.1 0.0003 20.8 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR66906.1 - 0.0004 20.3 0.4 0.00088 19.2 0.2 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMR66906.1 - 0.022 13.8 0.1 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMR66906.1 - 0.08 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EMR66906.1 - 0.086 11.4 0.2 0.13 10.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 EMR66906.1 - 0.097 11.1 0.3 0.15 10.5 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein PARP PF00644.15 EMR66908.1 - 2.3e-09 36.9 0.5 4.1e-09 36.1 0.4 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Sod_Cu PF00080.15 EMR66909.1 - 8.3e-46 155.6 6.2 9.6e-46 155.4 4.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SNase PF00565.12 EMR66911.1 - 1.2e-66 221.6 0.0 2.8e-21 75.8 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EMR66911.1 - 4.5e-25 87.8 0.0 2e-24 85.7 0.0 2.0 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 EMR66911.1 - 2.2e-06 27.0 0.0 6.7e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) DUF3334 PF11813.3 EMR66911.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) HATPase_c_3 PF13589.1 EMR66912.1 - 7.3e-07 28.9 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DPBB_1 PF03330.13 EMR66913.1 - 2.2e-06 27.5 0.0 3.4e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EMR66913.1 - 0.0025 17.4 0.2 0.0032 17.1 0.2 1.2 1 0 0 1 1 1 1 Barwin family Robl_LC7 PF03259.12 EMR66914.1 - 1.9e-08 33.7 0.2 4.1e-07 29.4 0.1 2.1 2 0 0 2 2 2 1 Roadblock/LC7 domain Menin PF05053.8 EMR66914.1 - 0.0042 15.3 3.7 0.0037 15.5 2.5 1.1 1 0 0 1 1 1 1 Menin Macoilin PF09726.4 EMR66914.1 - 0.054 11.7 6.7 0.053 11.8 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Pex14_N PF04695.8 EMR66914.1 - 6.2 6.8 11.2 66 3.5 7.8 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AMP-binding PF00501.23 EMR66916.1 - 3.6e-73 246.3 0.1 6.8e-73 245.4 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMR66916.1 - 1.9e-05 25.4 0.0 5.6e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DEAD PF00270.24 EMR66917.1 - 1.8e-37 128.3 0.0 3.1e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR66917.1 - 3.2e-24 84.5 0.0 4.8e-23 80.8 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR66917.1 - 4e-07 30.0 0.2 1.1e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EMR66917.1 - 0.00022 20.6 0.0 0.00029 20.2 0.0 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain CMS1 PF14617.1 EMR66917.1 - 0.034 13.2 0.1 0.22 10.5 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EMR66918.1 - 1.4e-39 135.2 0.0 2.4e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR66918.1 - 1.3e-20 72.9 1.9 1.3e-20 72.9 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMR66918.1 - 6.5e-06 25.1 0.0 9.6e-06 24.5 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 EMR66918.1 - 0.016 13.6 0.1 0.31 9.4 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 EMR66918.1 - 0.073 13.0 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain HPHLAWLY PF14925.1 EMR66919.1 - 0.00037 18.6 1.8 0.00065 17.8 1.1 1.4 1 1 1 2 2 2 1 Domain of unknown function Mg_trans_NIPA PF05653.9 EMR66919.1 - 0.0004 19.4 1.5 0.00048 19.1 1.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Metallophos PF00149.23 EMR66921.1 - 2.2e-13 50.0 0.0 1.3e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMR66921.1 - 1.5e-06 28.1 0.0 6.1e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RP-C_C PF11800.3 EMR66921.1 - 0.005 16.5 0.0 0.0076 15.9 0.0 1.2 1 0 0 1 1 1 1 Replication protein C C-terminal region ECH PF00378.15 EMR66922.1 - 3.6e-63 212.9 0.4 5.1e-63 212.4 0.3 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EMR66922.1 - 0.00098 18.9 0.1 0.0076 16.0 0.0 2.1 1 1 1 2 2 2 1 Peptidase family S49 ECH_C PF13766.1 EMR66922.1 - 0.084 13.0 0.0 0.22 11.6 0.0 1.6 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region Myc_N PF01056.13 EMR66923.1 - 0.69 9.0 6.8 1.6 7.7 4.7 1.6 1 1 0 1 1 1 0 Myc amino-terminal region PGA2 PF07543.7 EMR66923.1 - 4.7 6.9 10.9 10 5.8 7.5 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 MFMR PF07777.6 EMR66923.1 - 9.2 6.1 8.4 18 5.1 5.9 1.4 1 0 0 1 1 1 0 G-box binding protein MFMR Aminotran_1_2 PF00155.16 EMR66924.1 - 8.8e-20 70.9 0.0 5.4e-16 58.5 0.0 2.3 1 1 1 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMR66924.1 - 0.12 11.5 0.0 1.3 8.1 0.0 1.9 1 1 1 2 2 2 0 Beta-eliminating lyase DUF4411 PF14367.1 EMR66924.1 - 0.17 11.5 0.0 12 5.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4411) CorA PF01544.13 EMR66925.1 - 1.3e-15 57.2 0.4 1.9e-15 56.6 0.3 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sipho_Gp157 PF05565.6 EMR66925.1 - 0.0062 16.1 1.5 0.19 11.3 0.1 2.2 2 0 0 2 2 2 2 Siphovirus Gp157 DNA_repr_REX1B PF14966.1 EMR66925.1 - 0.12 12.8 0.1 12 6.3 0.0 2.3 2 0 0 2 2 2 0 DNA repair REX1-B Glyco_tran_WbsX PF14307.1 EMR66926.1 - 4.4e-36 124.7 0.2 7.8e-24 84.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase WbsX vATP-synt_E PF01991.13 EMR66927.1 - 3.8e-59 199.3 1.0 4.3e-59 199.1 0.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Ipi1_N PF12333.3 EMR66928.1 - 9.5e-18 64.0 0.0 1.7e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation CNH PF00780.17 EMR66929.1 - 5.8e-64 216.1 0.0 9.8e-64 215.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EMR66929.1 - 7.2e-28 97.6 0.6 1.1e-27 97.0 0.4 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EMR66929.1 - 2.1e-07 30.9 0.2 1.8e-06 27.9 0.0 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain Tropomyosin PF00261.15 EMR66929.1 - 0.0076 15.3 1.3 0.015 14.3 0.9 1.4 1 0 0 1 1 1 1 Tropomyosin SQS_PSY PF00494.14 EMR66930.1 - 1.7e-58 198.0 0.7 2.1e-58 197.7 0.5 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase 4HBT PF03061.17 EMR66931.1 - 6.3e-06 26.2 0.5 2.5e-05 24.3 0.1 2.0 2 0 0 2 2 2 1 Thioesterase superfamily Pex14_N PF04695.8 EMR66931.1 - 0.13 12.2 1.9 0.46 10.5 0.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CPSase_L_D2 PF02786.12 EMR66932.1 - 6.5e-113 375.1 0.3 5.2e-84 280.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EMR66932.1 - 2.2e-45 153.3 0.1 6.8e-45 151.7 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EMR66932.1 - 2.6e-44 150.9 0.0 8e-44 149.3 0.0 1.9 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EMR66932.1 - 4.3e-42 143.1 0.0 9.6e-42 141.9 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 EMR66932.1 - 1.8e-41 140.6 0.0 3.9e-20 72.0 0.0 3.7 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 EMR66932.1 - 4.5e-40 136.2 0.0 1.1e-39 135.0 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EMR66932.1 - 2.8e-36 125.0 0.2 7.8e-23 81.1 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 EMR66932.1 - 4.4e-35 120.9 0.0 9.4e-35 119.8 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 EMR66932.1 - 3.3e-23 81.9 0.0 2e-12 46.4 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EMR66932.1 - 2.2e-22 78.7 0.0 1.3e-21 76.2 0.0 2.5 2 0 0 2 2 1 1 MGS-like domain ATP-grasp PF02222.17 EMR66932.1 - 8.7e-18 64.2 0.2 7.1e-09 35.2 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMR66932.1 - 1.9e-14 53.5 0.8 1.2e-06 28.1 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.8 EMR66932.1 - 2.9e-06 26.8 0.4 8.1e-05 22.1 0.3 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 EMR66932.1 - 1.1e-05 25.3 0.5 0.11 12.2 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 EMR66932.1 - 2.3e-05 23.8 0.1 5.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family GARS_A PF01071.14 EMR66932.1 - 0.0032 17.0 0.2 3.6 7.1 0.0 2.9 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Aminotran_1_2 PF00155.16 EMR66933.1 - 1.8e-58 198.2 0.0 2.1e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 EMR66933.1 - 0.05 12.2 0.0 0.065 11.8 0.0 1.2 1 0 0 1 1 1 0 Allinase Cys_Met_Meta_PP PF01053.15 EMR66933.1 - 0.076 11.2 0.0 0.16 10.2 0.0 1.5 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Spc24 PF08286.6 EMR66934.1 - 1.3e-43 147.4 0.3 3.6e-40 136.3 0.0 2.1 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 Nsp1_C PF05064.8 EMR66934.1 - 0.0033 17.0 3.1 0.094 12.3 0.2 2.2 2 0 0 2 2 2 1 Nsp1-like C-terminal region Prefoldin_2 PF01920.15 EMR66934.1 - 0.0053 16.4 4.2 0.62 9.8 0.1 2.4 2 1 0 2 2 2 2 Prefoldin subunit Reo_sigmaC PF04582.7 EMR66934.1 - 0.0057 15.8 3.2 0.007 15.5 2.2 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein PTS_IIA PF02255.11 EMR66934.1 - 0.066 13.0 1.2 0.085 12.7 0.5 1.5 1 1 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit GvpG PF05120.7 EMR66934.1 - 0.093 12.5 2.9 0.22 11.3 2.0 1.6 1 0 0 1 1 1 0 Gas vesicle protein G APG6 PF04111.7 EMR66934.1 - 0.1 11.6 4.7 0.13 11.2 3.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Streptin-Immun PF11083.3 EMR66934.1 - 0.14 12.1 1.9 1.3 9.0 0.2 2.1 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein DUF4164 PF13747.1 EMR66934.1 - 0.21 11.7 8.2 0.29 11.2 5.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Vps5 PF09325.5 EMR66934.1 - 0.21 10.8 7.7 0.38 9.9 5.3 1.4 1 1 0 1 1 1 0 Vps5 C terminal like FlaC_arch PF05377.6 EMR66934.1 - 0.51 10.2 3.1 1.3 9.0 0.1 2.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) BRE1 PF08647.6 EMR66934.1 - 0.82 9.6 6.8 2.1 8.3 4.3 1.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Viral_P18 PF04521.8 EMR66934.1 - 2.9 7.3 6.8 0.79 9.1 0.9 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein IncA PF04156.9 EMR66934.1 - 3.1 7.3 14.2 8.5 5.9 9.8 1.6 1 1 0 1 1 1 0 IncA protein NTPase_I-T PF01931.13 EMR66936.1 - 0.097 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF84 MxiH PF09392.5 EMR66936.1 - 0.94 10.0 6.4 13 6.4 0.0 3.2 2 1 0 2 2 2 0 Type III secretion needle MxiH like Ndc1_Nup PF09531.5 EMR66936.1 - 2 6.7 7.7 0.15 10.4 2.2 1.4 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF1929 PF09118.6 EMR66938.1 - 2.2e-24 85.3 0.6 6.6e-24 83.8 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.20 EMR66938.1 - 5.9e-24 84.3 1.0 1.6e-23 82.9 0.7 1.7 1 0 0 1 1 1 1 F5/8 type C domain Kelch_6 PF13964.1 EMR66938.1 - 3e-14 52.4 6.7 4.2e-06 26.7 0.0 5.1 5 1 1 6 6 6 3 Kelch motif Kelch_4 PF13418.1 EMR66938.1 - 7.1e-12 44.9 10.4 2.3e-05 24.0 0.0 5.8 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EMR66938.1 - 9.5e-12 44.2 0.2 0.0003 20.2 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Glyoxal_oxid_N PF07250.6 EMR66938.1 - 4.2e-10 39.0 0.1 1.2e-05 24.5 0.3 2.5 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_3 PF13415.1 EMR66938.1 - 4.2e-06 26.7 10.6 0.086 13.0 0.0 5.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EMR66938.1 - 1.7e-05 24.3 0.1 0.89 9.4 0.1 3.7 3 0 0 3 3 3 2 Kelch motif DPBB_1 PF03330.13 EMR66938.1 - 0.013 15.4 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel RabGAP-TBC PF00566.13 EMR66939.1 - 8.4e-46 156.1 0.1 2.8e-45 154.4 0.0 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF1054 PF06335.7 EMR66939.1 - 1.6 8.3 5.8 2.2 7.9 1.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1054) Zip PF02535.17 EMR66940.1 - 0.16 10.9 8.9 0.27 10.1 6.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EMR66940.1 - 0.17 11.2 14.2 0.36 10.1 9.8 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.4 EMR66940.1 - 4.4 5.4 8.2 5.8 5.0 5.7 1.3 1 0 0 1 1 1 0 Transmembrane protein SHR3_chaperone PF08229.6 EMR66941.1 - 1.8e-70 235.9 0.0 2.1e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 MFS_1 PF07690.11 EMR66941.1 - 0.044 12.5 3.8 0.28 9.8 3.7 1.4 2 0 0 2 2 2 0 Major Facilitator Superfamily Pyridox_oxase_2 PF12766.2 EMR66942.1 - 1.8e-21 76.3 0.0 2.8e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DNA_topoisoIV PF00521.15 EMR66943.1 - 6e-112 374.6 0.9 6e-112 374.6 0.6 2.7 2 2 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EMR66943.1 - 1.8e-33 115.1 3.9 4.5e-33 113.9 2.7 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EMR66943.1 - 9.3e-13 48.0 0.0 4.1e-12 45.9 0.0 2.2 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EMR66943.1 - 7.3e-10 38.5 0.0 1.9e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_76 PF03663.9 EMR66944.1 - 1.3e-120 403.2 13.0 1.5e-120 402.9 9.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Reticulon PF02453.12 EMR66945.1 - 1.3e-39 135.4 2.8 2.1e-39 134.8 2.0 1.3 1 0 0 1 1 1 1 Reticulon DUF1043 PF06295.7 EMR66945.1 - 0.085 12.4 1.3 0.23 11.1 0.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) DUF2937 PF11157.3 EMR66945.1 - 0.12 11.7 2.0 0.46 9.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) FUSC_2 PF13515.1 EMR66945.1 - 0.28 11.1 4.8 0.93 9.4 0.2 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein-like TatD_DNase PF01026.16 EMR66946.1 - 3.9e-31 108.1 0.0 6.5e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase Trypan_PARP PF05887.6 EMR66946.1 - 0.00075 19.3 1.1 0.0021 17.9 0.8 1.8 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) RskA PF10099.4 EMR66947.1 - 0.0079 15.9 0.0 0.0086 15.8 0.0 1.0 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Cob_adeno_trans PF01923.13 EMR66947.1 - 0.13 12.0 0.1 0.13 12.0 0.1 1.0 1 0 0 1 1 1 0 Cobalamin adenosyltransferase TPR_11 PF13414.1 EMR66948.1 - 5.2e-11 42.0 3.8 4.7e-07 29.3 0.2 2.8 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EMR66948.1 - 1.4e-06 27.6 1.7 0.19 11.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMR66948.1 - 0.00011 21.7 6.3 0.31 11.0 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EMR66948.1 - 0.1 12.7 0.2 0.28 11.3 0.0 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ndc1_Nup PF09531.5 EMR66948.1 - 0.32 9.3 0.5 0.41 9.0 0.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_7 PF13176.1 EMR66948.1 - 0.38 10.6 6.5 3.7 7.5 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMR66948.1 - 0.85 10.4 4.1 1.1 10.0 1.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.27 EMR66949.1 - 1.5e-06 27.8 5.4 0.039 13.8 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat EHN PF06441.7 EMR66949.1 - 0.076 12.9 0.1 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Epoxide hydrolase N terminus zf-RING_2 PF13639.1 EMR66950.1 - 0.0052 16.5 3.9 0.006 16.3 0.3 2.2 2 0 0 2 2 2 1 Ring finger domain YjgP_YjgQ PF03739.9 EMR66951.1 - 0.18 10.5 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family RAP1 PF07218.6 EMR66951.1 - 7.4 4.5 8.1 12 3.8 5.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Fis1_TPR_C PF14853.1 EMR66952.1 - 8.7e-24 83.1 1.9 1.5e-23 82.3 1.3 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EMR66952.1 - 8.5e-18 63.3 0.0 1.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_16 PF13432.1 EMR66952.1 - 0.0039 17.8 0.2 0.0077 16.8 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMR66952.1 - 0.018 14.8 2.8 0.04 13.8 1.9 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_hydro_43 PF04616.9 EMR66953.1 - 2.8e-27 95.5 0.3 3.7e-27 95.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Mcp5_PH PF12814.2 EMR66954.1 - 1e-42 144.9 0.1 3.6e-42 143.1 0.0 2.1 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Glyco_hydro_61 PF03443.9 EMR66955.1 - 1.6e-53 181.7 0.1 1.8e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 EMR66957.1 - 7.4e-23 80.8 46.7 7.4e-23 80.8 32.4 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily zf-CCCH PF00642.19 EMR66958.1 - 4.1e-08 32.7 2.4 7.6e-08 31.8 1.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 EMR66958.1 - 8.3e-08 32.1 8.9 1.4e-07 31.3 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMR66958.1 - 1.1e-07 31.4 3.9 1.7e-07 30.8 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMR66958.1 - 3.2e-06 26.8 6.4 5.2e-06 26.1 4.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMR66958.1 - 6.4e-06 25.7 7.4 1.2e-05 24.8 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR66958.1 - 6.5e-06 25.7 6.7 1.1e-05 25.0 4.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMR66958.1 - 0.00089 19.0 7.9 0.002 17.9 5.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMR66958.1 - 0.012 15.3 3.1 0.035 13.8 2.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 EMR66958.1 - 0.082 13.0 0.4 0.21 11.7 0.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger Cript PF10235.4 EMR66958.1 - 7.2 7.0 9.0 3.2 8.1 3.7 2.4 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT adh_short PF00106.20 EMR66959.1 - 1.7e-26 93.1 0.4 1.5e-25 90.0 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR66959.1 - 3.1e-18 66.4 0.6 7.3e-18 65.2 0.4 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR66959.1 - 1.1e-09 38.1 0.7 3.3e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EMR66959.1 - 5e-07 29.8 0.5 6.3e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EMR66959.1 - 0.00031 20.8 0.2 0.0011 19.0 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 EMR66959.1 - 0.00033 19.7 0.2 0.00046 19.2 0.1 1.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase ADH_zinc_N PF00107.21 EMR66959.1 - 0.0043 16.5 0.2 0.01 15.3 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.10 EMR66959.1 - 0.016 14.0 0.2 0.027 13.3 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EMR66959.1 - 0.035 13.5 0.1 0.096 12.1 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EMR66959.1 - 0.09 13.2 0.2 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Snf7 PF03357.16 EMR66961.1 - 2.3e-07 30.3 28.4 2.5e-07 30.2 19.1 1.6 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.9 EMR66961.1 - 0.021 14.2 6.9 0.048 13.0 4.8 1.6 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway SATase_N PF06426.9 EMR66961.1 - 1.4 9.1 8.3 0.96 9.7 2.9 2.5 1 1 1 2 2 2 0 Serine acetyltransferase, N-terminal HD PF01966.17 EMR66962.1 - 1.5e-05 24.9 0.3 2.9e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 HD domain Peptidase_C12 PF01088.16 EMR66963.1 - 6.8e-61 205.1 0.0 7.7e-61 204.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Fungal_trans PF04082.13 EMR66964.1 - 9.6e-15 54.1 0.0 1.9e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDV3 PF15359.1 EMR66964.1 - 0.0096 15.9 1.3 0.02 14.9 0.9 1.4 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 zf-C4H2 PF10146.4 EMR66964.1 - 0.47 10.4 4.9 0.33 10.9 1.1 2.2 3 0 0 3 3 3 0 Zinc finger-containing protein NADH-u_ox-rdase PF10785.4 EMR66965.1 - 4.4e-36 122.9 0.5 8.7e-36 122.0 0.4 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EMR66965.1 - 1.2e-31 108.2 0.0 1.9e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Curlin_rpt PF07012.7 EMR66966.1 - 1.6 8.5 12.5 2.9 7.7 1.5 3.4 3 2 1 4 4 4 0 Curlin associated repeat bZIP_2 PF07716.10 EMR66967.1 - 5.2e-08 32.5 13.0 1e-07 31.6 9.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EMR66967.1 - 3.7e-06 26.7 18.9 6.5e-06 26.0 13.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EMR66967.1 - 0.0055 16.9 11.6 0.0096 16.1 8.0 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor AAA_13 PF13166.1 EMR66967.1 - 0.014 13.8 0.9 0.019 13.4 0.6 1.1 1 0 0 1 1 1 0 AAA domain Herpes_UL25 PF01499.11 EMR66967.1 - 0.078 11.2 1.5 0.096 10.9 1.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF641 PF04859.7 EMR66967.1 - 0.11 12.2 4.9 0.19 11.5 3.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) TMEM247 PF15444.1 EMR66967.1 - 0.2 11.4 3.1 0.4 10.4 2.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 Atg14 PF10186.4 EMR66967.1 - 1 8.2 6.0 1.4 7.7 4.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EMR66967.1 - 1.9 7.4 5.6 2.8 6.9 3.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 EMR66967.1 - 2.2 7.9 8.4 3.5 7.2 5.8 1.2 1 0 0 1 1 1 0 Mnd1 family Pex16 PF08610.5 EMR66968.1 - 2e-101 339.3 0.1 2.2e-101 339.2 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Nucleos_tra2_N PF01773.15 EMR66968.1 - 0.16 12.3 0.8 9.1 6.7 0.1 2.3 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus BNR_2 PF13088.1 EMR66969.1 - 2.1e-20 73.1 1.4 2.7e-15 56.4 0.1 2.4 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EMR66969.1 - 0.00053 19.4 28.6 0.027 14.2 0.6 6.2 6 1 0 6 6 6 4 BNR/Asp-box repeat Bravo_FIGEY PF13882.1 EMR66969.1 - 0.13 13.2 0.0 0.27 12.1 0.0 1.5 1 0 0 1 1 1 0 Bravo-like intracellular region Swi3 PF07962.7 EMR66970.1 - 2.4e-30 103.9 0.3 5.7e-30 102.7 0.2 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Pectinesterase PF01095.14 EMR66971.1 - 9.2e-150 497.2 102.1 2.4e-46 157.6 4.1 7.6 8 1 1 9 9 9 5 Pectinesterase DSHCT PF08148.7 EMR66972.1 - 5.5e-61 204.9 0.9 9.7e-61 204.1 0.6 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EMR66972.1 - 1.9e-20 73.0 0.0 5e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR66972.1 - 1.7e-06 27.8 1.4 3.1e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 EMR66972.1 - 0.0071 15.5 0.9 0.076 12.1 0.1 2.4 3 0 0 3 3 3 1 rRNA-processing arch domain ResIII PF04851.10 EMR66972.1 - 0.025 14.4 0.0 0.33 10.7 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Cellulase PF00150.13 EMR66973.1 - 3.2e-19 69.2 4.6 4.8e-19 68.6 3.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Oxysterol_BP PF01237.13 EMR66974.1 - 8.5e-124 412.6 0.0 2.4e-123 411.1 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 EMR66974.1 - 9.4e-17 61.1 0.0 9.7e-11 41.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMR66974.1 - 1.4e-15 56.9 0.7 3.2e-08 33.5 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EMR66974.1 - 7.3e-15 53.9 0.2 0.00038 20.1 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EMR66974.1 - 3.5e-13 48.3 0.0 0.001 19.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EMR66974.1 - 3.8e-13 49.5 0.1 2.3e-06 27.9 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.24 EMR66974.1 - 1.2e-12 47.9 0.2 2.7e-12 46.7 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMR66974.1 - 6.6e-10 39.2 1.0 1.8e-09 37.8 0.7 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EMR66974.1 - 3.1e-08 33.5 0.9 8e-08 32.2 0.6 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain ACPS PF01648.15 EMR66976.1 - 1.1e-05 25.1 0.0 2.9e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DLH PF01738.13 EMR66977.1 - 1e-12 47.7 0.0 1.2e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMR66977.1 - 2.2e-05 24.2 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR66977.1 - 0.0068 16.3 0.0 0.017 15.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Xpo1 PF08389.7 EMR66979.1 - 0.016 15.1 0.0 0.24 11.2 0.0 2.4 2 0 0 2 2 2 0 Exportin 1-like protein 4HBT_3 PF13622.1 EMR66980.1 - 5.5e-45 154.1 10.5 1.8e-44 152.4 7.3 1.7 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMR66980.1 - 1.7e-23 82.7 0.0 3.7e-11 42.7 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Peptidase_M28 PF04389.12 EMR66981.1 - 7.4e-28 97.4 0.4 7.4e-28 97.4 0.3 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EMR66981.1 - 0.0003 20.3 1.1 0.00052 19.5 0.7 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DEP PF00610.16 EMR66981.1 - 0.015 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP12 PF07542.6 EMR66982.1 - 1.5e-28 99.2 0.0 2.4e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein DUF4317 PF14199.1 EMR66984.1 - 0.068 11.9 0.0 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) MOSC PF03473.12 EMR66985.1 - 3.4e-07 29.8 0.2 6.2e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.22 EMR66985.1 - 6.5e-07 29.0 0.9 1.5e-06 27.8 0.6 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.19 EMR66985.1 - 7.2e-06 26.0 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMR66985.1 - 0.028 15.0 0.1 0.15 12.6 0.1 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Fer2_3 PF13085.1 EMR66985.1 - 0.14 12.0 0.4 0.34 10.7 0.3 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Peptidase_S49_N PF08496.5 EMR66986.1 - 0.034 13.9 2.0 0.1 12.3 1.4 1.8 1 1 0 1 1 1 0 Peptidase family S49 N-terminal Metallophos PF00149.23 EMR66987.1 - 7.4e-05 22.2 0.4 0.00024 20.5 0.3 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Antimicrobial11 PF08106.6 EMR66987.1 - 9.7 6.2 7.0 0.5 10.2 0.9 1.9 2 0 0 2 2 2 0 Formaecin family DUF1996 PF09362.5 EMR66988.1 - 2e-61 207.6 0.0 2.4e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Abhydrolase_5 PF12695.2 EMR66990.1 - 2.2e-09 37.2 0.3 3.7e-09 36.4 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EMR66990.1 - 5.5e-08 32.3 3.3 9.4e-08 31.5 2.0 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EMR66990.1 - 4.8e-07 29.2 0.0 7.9e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EMR66990.1 - 3.4e-05 23.5 0.1 6.4e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR66990.1 - 0.0001 22.2 7.1 0.00066 19.6 4.9 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EMR66990.1 - 0.0048 15.4 0.1 0.0066 14.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 EMR66990.1 - 0.081 12.4 1.2 0.23 10.9 0.6 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold YL1 PF05764.8 EMR66991.1 - 0.026 14.1 8.4 0.035 13.7 5.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 EMR66991.1 - 0.13 10.3 8.6 0.16 9.9 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Upf2 PF04050.9 EMR66991.1 - 0.21 11.3 5.0 0.31 10.7 3.4 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Nop14 PF04147.7 EMR66991.1 - 0.51 8.1 14.5 0.64 7.8 10.0 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EMR66991.1 - 0.79 8.1 7.2 0.98 7.8 5.0 1.1 1 0 0 1 1 1 0 Daxx Family NDUF_B12 PF08122.7 EMR66992.1 - 0.084 12.6 0.4 0.48 10.1 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF1049 PF06305.6 EMR66992.1 - 1.4 8.4 4.9 1.2 8.7 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Septin PF00735.13 EMR66993.1 - 4.5e-112 373.6 0.6 5.3e-112 373.4 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EMR66993.1 - 2.1e-06 27.6 0.0 4.2e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EMR66993.1 - 1.5e-05 24.2 0.0 2.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 EMR66993.1 - 3.6e-05 23.2 0.6 0.014 14.8 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMR66993.1 - 0.00013 21.1 0.0 0.00025 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EMR66993.1 - 0.00091 19.0 1.2 0.65 9.8 0.1 2.6 2 1 1 3 3 3 2 Dynamin family AAA_10 PF12846.2 EMR66993.1 - 0.0024 17.3 0.1 0.0024 17.3 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EMR66993.1 - 0.015 15.4 0.0 0.036 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMR66993.1 - 0.019 15.2 0.8 0.029 14.6 0.4 1.7 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EMR66993.1 - 0.022 15.1 0.0 0.044 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EMR66993.1 - 0.024 14.1 0.1 0.054 12.9 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EMR66993.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 EMR66993.1 - 0.032 13.1 0.0 0.097 11.5 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 EMR66993.1 - 0.032 13.0 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Gtr1_RagA PF04670.7 EMR66993.1 - 0.04 13.0 0.1 0.58 9.2 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EMR66993.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PAP2 PF01569.16 EMR66994.1 - 3.1e-16 59.2 4.2 3.1e-16 59.2 2.9 2.1 2 1 0 2 2 2 1 PAP2 superfamily MFS_1 PF07690.11 EMR66995.1 - 3.3e-30 105.0 23.8 3.9e-30 104.7 16.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EMR66995.1 - 0.0002 21.1 0.6 0.0002 21.1 0.4 2.4 2 0 0 2 2 2 1 MFS_1 like family zf-MYND PF01753.13 EMR66996.1 - 2.8e-11 43.0 11.6 4.8e-11 42.3 8.0 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EMR66996.1 - 2.4 7.8 7.9 3.1 7.4 2.5 2.3 2 0 0 2 2 2 0 HIT zinc finger Fer4_21 PF14697.1 EMR66998.1 - 4 7.3 7.3 7 6.5 5.1 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain MFS_1 PF07690.11 EMR66999.1 - 2.9e-33 115.0 11.6 4.9e-33 114.3 7.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily 7TM-7TMR_HD PF07698.6 EMR66999.1 - 0.0056 16.1 0.3 0.0056 16.1 0.2 2.7 3 1 0 3 3 3 1 7TM receptor with intracellular HD hydrolase Macro PF01661.16 EMR67000.1 - 5.7e-23 81.0 0.0 1.3e-22 79.8 0.0 1.6 1 1 0 1 1 1 1 Macro domain DNA_pol_delta_4 PF04081.8 EMR67001.1 - 5.1e-30 104.3 3.2 7.2e-30 103.8 2.2 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Rrp15p PF07890.7 EMR67001.1 - 0.041 13.9 8.2 0.063 13.3 5.7 1.2 1 0 0 1 1 1 0 Rrp15p PRP1_N PF06424.7 EMR67001.1 - 0.052 13.8 3.1 0.073 13.3 2.1 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal CDC45 PF02724.9 EMR67001.1 - 0.12 10.3 2.6 0.15 10.0 1.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 EMR67001.1 - 0.23 11.2 3.9 0.33 10.7 2.7 1.2 1 0 0 1 1 1 0 DDHD domain TauD PF02668.11 EMR67003.1 - 2.5e-50 171.5 1.4 3.2e-50 171.2 0.9 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Beta_helix PF13229.1 EMR67003.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Right handed beta helix region Glyco_hydro_43 PF04616.9 EMR67004.1 - 2.1e-32 112.3 2.5 3.3e-32 111.7 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 APH PF01636.18 EMR67004.1 - 2.9e-11 43.5 0.0 1.5e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EMR67004.1 - 0.0013 17.4 0.0 0.0019 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EMR67004.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 EMR67004.1 - 0.25 10.8 0.0 0.43 10.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase tRNA_int_end_N2 PF12928.2 EMR67005.1 - 1.4e-17 62.8 0.4 5.1e-17 61.0 0.3 1.9 1 1 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term ThiF PF00899.16 EMR67006.1 - 6.1e-41 139.4 0.2 1.3e-40 138.3 0.1 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EMR67006.1 - 3.5e-30 103.3 2.0 4.9e-30 102.9 0.2 2.2 3 0 0 3 3 3 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 EMR67006.1 - 1.1e-20 73.5 0.9 1.1e-20 73.5 0.6 2.3 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 EMR67006.1 - 2.7e-20 71.4 0.6 2.7e-20 71.4 0.4 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EMR67006.1 - 0.0002 21.4 0.1 0.00042 20.4 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EMR67006.1 - 0.00043 20.4 0.1 0.0016 18.6 0.1 2.0 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.22 EMR67006.1 - 0.02 15.2 0.1 0.39 11.1 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 EMR67006.1 - 0.077 11.9 0.3 0.16 10.9 0.2 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase ADH_zinc_N PF00107.21 EMR67007.1 - 5.5e-27 93.8 0.2 9.2e-27 93.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR67007.1 - 6.8e-15 56.0 0.1 1.5e-14 54.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR67007.1 - 7.3e-10 38.5 0.0 1.3e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EMR67007.1 - 0.032 13.8 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EMR67007.1 - 0.073 13.0 0.0 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain DUF2419 PF10343.4 EMR67009.1 - 3e-101 338.4 0.0 5e-76 255.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2419) DUF1563 PF07599.6 EMR67009.1 - 0.038 13.8 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) Tet_JBP PF12851.2 EMR67010.1 - 2e-06 27.1 0.0 3.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily WD40 PF00400.27 EMR67011.1 - 8.8e-29 98.3 11.6 1.3e-10 40.7 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EMR67011.1 - 0.00073 19.2 0.0 0.04 13.6 0.0 3.0 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EMR67011.1 - 0.0021 16.3 0.0 0.01 14.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome D1 heme domain Nbas_N PF15492.1 EMR67011.1 - 0.024 13.7 0.1 9.5 5.2 0.0 3.2 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EMR67011.1 - 0.06 11.4 0.0 5 5.1 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DNA_binding_1 PF01035.15 EMR67012.1 - 3.3e-25 87.6 0.0 5.9e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ribosomal_60s PF00428.14 EMR67012.1 - 0.0064 16.8 5.5 0.01 16.2 3.8 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein PBP1_TM PF14812.1 EMR67012.1 - 0.014 15.6 0.5 0.025 14.8 0.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 EMR67012.1 - 0.026 13.6 4.2 0.036 13.2 2.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 EMR67012.1 - 0.043 12.3 6.6 0.056 11.9 4.6 1.0 1 0 0 1 1 1 0 Daxx Family DUF4599 PF15371.1 EMR67012.1 - 0.059 13.4 0.3 0.059 13.4 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) Pro_Al_protease PF02983.9 EMR67013.1 - 0.00021 21.1 3.1 0.00021 21.1 2.2 2.6 2 0 0 2 2 2 1 Alpha-lytic protease prodomain MFS_1 PF07690.11 EMR67014.1 - 6e-07 28.4 26.2 6e-07 28.4 18.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMR67014.1 - 2.1e-05 24.0 5.4 3.5e-05 23.3 2.7 2.2 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EMR67014.1 - 0.02 13.5 10.1 0.042 12.4 6.7 1.5 1 1 0 1 1 1 0 Sugar (and other) transporter Sulfatase PF00884.18 EMR67015.1 - 4.4e-35 121.3 0.1 8.2e-35 120.4 0.1 1.4 1 0 0 1 1 1 1 Sulfatase F-box-like PF12937.2 EMR67016.1 - 6e-08 32.2 0.1 1.7e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMR67016.1 - 1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain Rhabdo_M2 PF04785.7 EMR67016.1 - 0.019 14.0 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 Git3_C PF11970.3 EMR67017.1 - 4.2e-17 61.6 0.1 4.2e-17 61.6 0.1 2.5 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Nucleoplasmin PF03066.10 EMR67017.1 - 0.11 11.9 2.4 6.8 6.2 2.9 2.1 2 0 0 2 2 2 0 Nucleoplasmin Cu-oxidase_3 PF07732.10 EMR67017.1 - 0.64 9.7 4.7 0.98 9.1 3.2 1.2 1 0 0 1 1 1 0 Multicopper oxidase Nop14 PF04147.7 EMR67017.1 - 3.5 5.4 9.9 4.9 4.9 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4611 PF15387.1 EMR67017.1 - 3.9 7.6 8.8 36 4.5 5.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RXT2_N PF08595.6 EMR67017.1 - 6.9 6.4 8.3 27 4.5 2.5 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Hydantoinase_B PF02538.9 EMR67018.1 - 5e-172 572.8 0.0 6.3e-172 572.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EMR67018.1 - 1.4e-90 303.3 0.2 3.2e-90 302.1 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EMR67018.1 - 1.1e-56 191.1 1.1 7.4e-55 185.1 0.0 3.3 4 0 0 4 4 4 1 Hydantoinase/oxoprolinase N-terminal region Arrestin_C PF02752.17 EMR67019.1 - 1.8e-13 50.7 0.1 2.4e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain adh_short PF00106.20 EMR67020.1 - 4.1e-25 88.6 5.5 1.6e-24 86.7 3.8 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR67020.1 - 2.3e-23 83.2 0.1 2.9e-23 82.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR67020.1 - 2.9e-06 27.0 2.3 5.2e-06 26.2 1.6 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR67020.1 - 0.00018 20.9 1.6 0.022 14.2 0.4 3.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EMR67020.1 - 0.0031 17.1 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EMR67020.1 - 0.0092 15.7 0.2 0.023 14.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EMR67020.1 - 0.012 14.6 0.0 0.095 11.7 0.0 2.2 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GspH PF12019.3 EMR67020.1 - 0.039 14.1 0.4 0.064 13.4 0.3 1.3 1 0 0 1 1 1 0 Type II transport protein GspH NAD_binding_10 PF13460.1 EMR67020.1 - 0.08 12.9 2.5 0.44 10.5 0.8 2.1 1 1 1 2 2 2 0 NADH(P)-binding Glyco_hydro_72 PF03198.9 EMR67021.1 - 2.8e-114 381.3 0.3 3.4e-114 381.0 0.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EMR67021.1 - 0.00095 18.1 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Lectin_N PF03954.9 EMR67021.1 - 0.012 14.9 2.9 0.045 13.1 2.0 1.9 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DAO PF01266.19 EMR67022.1 - 1e-37 129.9 0.0 4e-37 127.9 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR67022.1 - 6.2e-06 26.1 0.0 1.9e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMR67022.1 - 0.00021 20.2 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EMR67022.1 - 0.00025 20.8 0.3 0.0016 18.1 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EMR67022.1 - 0.0012 19.1 0.0 1.3 9.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR67022.1 - 0.0016 18.3 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EMR67022.1 - 0.0028 17.4 0.0 0.0067 16.2 0.0 1.6 1 0 0 1 1 1 1 ThiF family Pyr_redox_3 PF13738.1 EMR67022.1 - 0.0037 17.3 0.0 0.009 16.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMR67022.1 - 0.017 15.1 0.0 0.04 13.9 0.0 1.6 2 0 0 2 2 1 0 TrkA-N domain FAD_binding_3 PF01494.14 EMR67022.1 - 0.024 13.6 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 EMR67022.1 - 0.054 13.6 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 EMR67022.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EMR67022.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 EMR67022.1 - 0.21 10.3 0.0 0.76 8.5 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_4 PF07993.7 EMR67023.1 - 6.9e-33 113.6 0.0 1.1e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EMR67023.1 - 6.1e-09 35.6 0.0 2.2e-08 33.8 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMR67023.1 - 1.6e-06 28.2 0.0 4.2e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.19 EMR67023.1 - 0.00017 21.9 0.1 0.001 19.3 0.0 2.4 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EMR67023.1 - 0.013 14.2 0.0 0.03 13.0 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family P2X_receptor PF00864.14 EMR67023.1 - 0.17 10.5 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 ATP P2X receptor Pro_isomerase PF00160.16 EMR67024.1 - 1.3e-41 142.4 0.0 1.4e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ubiquitin PF00240.18 EMR67025.1 - 0.0017 17.7 0.0 0.0027 17.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Glyco_hydro_16 PF00722.16 EMR67026.1 - 2.9e-15 56.0 1.1 4.1e-15 55.5 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EMR67026.1 - 0.067 11.3 6.8 0.38 8.8 4.7 1.9 1 1 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Laminin_G_2 PF02210.19 EMR67026.1 - 0.095 12.7 0.0 0.77 9.8 0.0 2.1 2 0 0 2 2 2 0 Laminin G domain tRNA_bind_2 PF13725.1 EMR67027.1 - 0.076 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain GATase PF00117.23 EMR67028.1 - 8.9e-12 44.8 0.0 1.1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EMR67028.1 - 0.00028 20.3 0.1 0.0017 17.8 0.1 2.0 2 1 0 2 2 2 1 Peptidase C26 GATase_3 PF07685.9 EMR67028.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.11 EMR67029.1 - 1.3e-39 135.9 71.3 2.4e-32 112.0 26.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YesK PF14150.1 EMR67029.1 - 0.8 9.8 8.6 0.055 13.5 0.8 2.9 4 0 0 4 4 4 0 YesK-like protein LRR_8 PF13855.1 EMR67030.1 - 0.005 16.5 1.6 2 8.2 0.1 3.5 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EMR67030.1 - 0.081 12.5 1.4 0.17 11.5 0.2 2.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) AA_permease PF00324.16 EMR67031.1 - 3.6e-98 328.9 28.8 4.1e-98 328.8 20.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR67031.1 - 2.2e-30 105.5 33.7 2.4e-30 105.4 23.3 1.0 1 0 0 1 1 1 1 Amino acid permease FUSC-like PF12805.2 EMR67031.1 - 4.8 6.0 11.1 2 7.2 3.4 2.1 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Med8 PF10232.4 EMR67032.1 - 0.018 14.5 0.6 0.025 14.0 0.4 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Shisa PF13908.1 EMR67033.1 - 7.5e-05 22.9 11.8 0.00012 22.2 0.2 2.3 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 EMR67033.1 - 0.0042 16.7 0.4 0.015 15.0 0.3 2.0 1 1 0 1 1 1 1 TMEM154 protein family Rax2 PF12768.2 EMR67033.1 - 0.0075 15.5 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Romo1 PF10247.4 EMR67033.1 - 0.036 14.2 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF605 PF04652.11 EMR67033.1 - 0.054 12.8 5.2 0.067 12.5 3.6 1.1 1 0 0 1 1 1 0 Vta1 like Gram_pos_anchor PF00746.16 EMR67033.1 - 0.23 11.3 3.5 0.44 10.4 2.4 1.5 1 0 0 1 1 1 0 Gram positive anchor Podoplanin PF05808.6 EMR67033.1 - 0.33 10.5 5.6 0.64 9.5 3.2 1.8 1 1 1 2 2 2 0 Podoplanin Alpha_GJ PF03229.8 EMR67033.1 - 3.4 8.0 9.7 0.4 11.0 3.0 2.1 1 1 1 2 2 2 0 Alphavirus glycoprotein J Nitrate_red_gam PF02665.9 EMR67033.1 - 3.6 6.8 4.3 0.78 9.0 0.2 1.9 3 0 0 3 3 3 0 Nitrate reductase gamma subunit Trp_DMAT PF11991.3 EMR67034.1 - 7.6e-66 222.7 0.0 1.2e-65 222.0 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Peptidase_M20 PF01546.23 EMR67035.1 - 2.5e-08 33.6 0.0 3.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMR67035.1 - 9.3e-07 28.5 0.0 1.7e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase dimerisation domain Acetyltransf_1 PF00583.19 EMR67036.1 - 0.00023 21.1 0.0 0.00045 20.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 EMR67036.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EMR67036.1 - 0.1 12.4 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Abi_HHR PF07815.9 EMR67037.1 - 0.026 14.6 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Abl-interactor HHR Sugar_tr PF00083.19 EMR67038.1 - 2.2e-54 184.7 15.3 1.1e-47 162.6 7.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR67038.1 - 4.2e-07 29.0 22.2 5.3e-07 28.6 15.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ketoacyl-synt PF00109.21 EMR67039.1 - 1.1e-64 218.3 0.0 2.1e-64 217.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMR67039.1 - 4.8e-34 116.7 0.0 1.1e-33 115.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EMR67039.1 - 4.6e-29 101.7 0.0 1.4e-26 93.5 0.0 2.3 2 0 0 2 2 2 2 Acyl transferase domain NAD_binding_4 PF07993.7 EMR67039.1 - 9.5e-16 57.4 0.0 1.7e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EMR67039.1 - 1.5e-14 54.2 0.0 6.6e-14 52.1 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 EMR67039.1 - 3.6e-11 43.1 0.3 9.1e-11 41.8 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 EMR67039.1 - 5.3e-10 39.0 0.0 1.4e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR67039.1 - 2e-07 30.8 0.0 1.1e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Amidase PF01425.16 EMR67039.1 - 1.9e-06 27.0 0.0 3.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Amidase Methyltransf_11 PF08241.7 EMR67039.1 - 4.1e-06 27.1 0.0 3.1e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 EMR67039.1 - 1.4e-05 24.1 0.1 5.8e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 EMR67039.1 - 1.9e-05 24.6 0.0 0.00024 21.0 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR67039.1 - 6.1e-05 23.5 0.0 0.00026 21.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR67039.1 - 9.9e-05 22.6 0.0 0.00038 20.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR67039.1 - 0.042 12.9 0.0 0.09 11.8 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.6 EMR67039.1 - 0.063 12.6 0.0 0.24 10.7 0.0 1.9 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_31 PF13847.1 EMR67040.1 - 2.4e-07 30.4 0.0 1.5e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR67040.1 - 7.9e-06 25.6 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR67040.1 - 3.6e-05 24.2 0.0 0.00034 21.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR67040.1 - 0.00038 20.9 0.0 0.00079 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR67040.1 - 0.011 16.1 0.0 0.029 14.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EMR67040.1 - 0.028 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMR67040.1 - 0.043 14.1 0.0 0.15 12.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EMR67040.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 EMR67041.1 - 2.8e-29 102.0 0.1 1.5e-28 99.6 0.1 2.0 1 1 0 1 1 1 1 O-methyltransferase FAD_binding_4 PF01565.18 EMR67042.1 - 1.9e-14 53.2 0.2 1e-11 44.4 0.0 2.7 2 1 1 3 3 3 2 FAD binding domain BBE PF08031.7 EMR67042.1 - 5e-06 26.3 0.6 9.7e-06 25.4 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like FAD_binding_4 PF01565.18 EMR67043.1 - 5.2e-13 48.6 0.0 8.1e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF1479 PF07350.7 EMR67044.1 - 4.8e-113 377.7 0.9 3.3e-72 243.2 1.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.8 EMR67044.1 - 0.0064 16.5 0.4 0.47 10.4 0.1 2.4 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) PAS_3 PF08447.6 EMR67044.1 - 0.05 13.7 0.1 4.1 7.5 0.0 2.6 2 0 0 2 2 2 0 PAS fold Amino_oxidase PF01593.19 EMR67047.1 - 6.6e-57 193.5 0.0 8.9e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMR67047.1 - 1.9e-09 37.3 0.0 1.5e-08 34.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR67047.1 - 0.00019 21.5 0.0 0.00073 19.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR67047.1 - 0.00029 19.8 0.0 0.00047 19.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR67047.1 - 0.0007 18.5 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EMR67047.1 - 0.003 16.7 0.1 0.0053 15.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EMR67047.1 - 0.0039 16.2 0.4 0.0065 15.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMR67047.1 - 0.0047 17.2 0.4 0.031 14.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR67047.1 - 0.018 13.5 0.4 0.027 12.9 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EMR67047.1 - 0.066 12.9 0.2 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding DIOX_N PF14226.1 EMR67048.1 - 1.5e-28 99.6 0.0 2.1e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMR67048.1 - 1.9e-22 79.4 0.0 5e-22 78.0 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 EMR67049.1 - 3.9e-09 36.6 0.0 8.4e-09 35.5 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR67049.1 - 0.0024 17.5 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR67049.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EMR67049.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Snf7 PF03357.16 EMR67050.1 - 1.6e-36 125.2 3.9 2e-36 124.9 2.7 1.1 1 0 0 1 1 1 1 Snf7 Nup54 PF13874.1 EMR67050.1 - 0.049 13.2 10.1 0.29 10.8 0.0 3.1 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 OSCP PF00213.13 EMR67051.1 - 1.6e-42 145.3 4.3 2.1e-42 144.9 3.0 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Acyl_transf_1 PF00698.16 EMR67052.1 - 6.3e-54 183.4 0.0 9.9e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EMR67052.1 - 8.2e-47 159.8 0.0 1.2e-28 100.3 0.0 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMR67052.1 - 2.8e-37 127.1 0.2 2e-36 124.4 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EMR67052.1 - 2.7e-35 121.9 0.0 5.1e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EMR67052.1 - 1.1e-23 83.8 0.1 6.8e-23 81.2 0.0 2.4 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.21 EMR67052.1 - 5.1e-21 74.5 0.0 3e-20 72.0 0.0 2.4 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMR67052.1 - 8.1e-15 55.1 0.0 4e-14 52.8 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.20 EMR67052.1 - 2.6e-14 53.5 0.0 8e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EMR67052.1 - 3.8e-12 47.2 0.0 6.7e-11 43.1 0.0 3.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EMR67052.1 - 1.8e-11 44.0 0.0 5.2e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR67052.1 - 5.2e-10 39.1 0.0 1.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR67052.1 - 9.3e-08 32.4 0.0 2.8e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR67052.1 - 5.5e-07 30.1 0.0 2.8e-06 27.8 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR67052.1 - 0.00064 20.0 0.0 0.0025 18.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR67052.1 - 0.0012 17.9 0.0 0.0026 16.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EMR67052.1 - 0.043 13.8 0.0 0.17 11.9 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 EMR67052.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_PK PF05891.7 EMR67052.1 - 0.13 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase 2OG-FeII_Oxy_3 PF13640.1 EMR67054.1 - 2e-11 44.3 0.0 4.1e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EMR67054.1 - 9.9e-06 25.1 0.1 3.6e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SNF2_N PF00176.18 EMR67055.1 - 4e-70 235.9 2.1 4e-70 235.9 1.4 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 EMR67055.1 - 5.4e-52 175.5 15.1 5.4e-52 175.5 10.5 5.1 4 2 1 5 5 5 1 DNA-binding domain Helicase_C PF00271.26 EMR67055.1 - 2.3e-16 59.4 0.0 6.6e-16 57.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Lipase_3 PF01764.20 EMR67056.1 - 1.8e-21 76.2 0.0 3.4e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EMR67056.1 - 0.12 11.7 0.1 4.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) RAI16-like PF10257.4 EMR67057.1 - 2.2e-46 158.4 0.0 3.7e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein 2OG-FeII_Oxy_3 PF13640.1 EMR67058.1 - 0.0028 18.1 0.0 0.007 16.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMR67058.1 - 0.035 14.4 0.0 0.62 10.3 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily ABC_tran PF00005.22 EMR67059.1 - 5.8e-45 152.9 0.0 2.6e-21 76.3 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EMR67059.1 - 3e-19 68.6 7.4 3e-19 68.6 5.1 3.3 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 EMR67059.1 - 4.4e-18 66.2 0.1 0.0015 18.5 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EMR67059.1 - 1.6e-11 43.8 0.0 0.00018 20.8 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMR67059.1 - 8.7e-09 35.9 2.1 0.021 15.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EMR67059.1 - 1.2e-08 34.2 0.0 0.0049 16.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EMR67059.1 - 4.7e-07 30.6 0.0 0.0096 16.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EMR67059.1 - 1.5e-06 28.5 2.1 0.017 15.4 0.0 3.3 4 0 0 4 4 2 2 AAA domain DUF258 PF03193.11 EMR67059.1 - 1.9e-06 27.1 0.0 0.0029 16.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EMR67059.1 - 5.7e-06 26.4 1.4 1.7 8.8 0.0 3.6 3 0 0 3 3 3 2 RNA helicase AAA_22 PF13401.1 EMR67059.1 - 7.4e-06 26.1 0.0 0.14 12.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EMR67059.1 - 1.1e-05 25.3 0.4 0.069 13.1 0.1 3.1 3 1 0 3 3 2 2 50S ribosome-binding GTPase Miro PF08477.8 EMR67059.1 - 1.9e-05 25.1 0.0 0.064 13.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_28 PF13521.1 EMR67059.1 - 3e-05 24.0 0.0 0.02 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMR67059.1 - 3.5e-05 23.5 0.1 0.16 11.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_5 PF07728.9 EMR67059.1 - 5e-05 23.0 0.1 0.25 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMR67059.1 - 5.1e-05 23.3 1.7 0.29 11.0 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.24 EMR67059.1 - 5.7e-05 23.3 0.0 0.43 10.7 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EMR67059.1 - 8.7e-05 22.3 0.1 0.15 11.7 0.0 3.2 3 0 0 3 3 3 1 Archaeal ATPase AAA_15 PF13175.1 EMR67059.1 - 0.00014 21.0 0.0 0.11 11.4 0.0 3.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 EMR67059.1 - 0.00017 21.5 0.1 0.12 12.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EMR67059.1 - 0.00062 19.2 0.0 1.5 8.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.1 EMR67059.1 - 0.0008 19.3 0.0 2.3 8.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EMR67059.1 - 0.0016 17.9 1.7 1.2 8.5 0.2 3.0 4 0 0 4 4 3 2 AAA-like domain DAP3 PF10236.4 EMR67059.1 - 0.0036 16.2 0.5 2.2 7.1 0.0 3.5 4 0 0 4 4 4 1 Mitochondrial ribosomal death-associated protein 3 MobB PF03205.9 EMR67059.1 - 0.0038 16.9 0.0 0.22 11.2 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2813 PF11398.3 EMR67059.1 - 0.0089 15.1 1.5 0.82 8.6 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) NB-ARC PF00931.17 EMR67059.1 - 0.0092 14.8 0.6 1.5 7.6 0.0 3.1 4 0 0 4 4 4 1 NB-ARC domain Dynamin_N PF00350.18 EMR67059.1 - 0.015 15.1 0.9 12 5.6 0.0 3.4 3 1 1 4 4 4 0 Dynamin family SbcCD_C PF13558.1 EMR67059.1 - 0.032 14.1 0.5 1.2 9.1 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 EMR67059.1 - 0.032 13.7 0.6 6.8 6.1 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 EMR67059.1 - 0.038 12.9 0.0 2.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 EMR67059.1 - 0.042 13.5 0.1 7 6.3 0.1 2.7 2 0 0 2 2 2 0 NTPase MCM PF00493.18 EMR67059.1 - 0.058 12.1 0.9 8 5.1 0.0 2.6 3 0 0 3 3 3 0 MCM2/3/5 family ArgK PF03308.11 EMR67059.1 - 0.069 11.9 1.7 11 4.7 0.0 3.2 3 0 0 3 3 3 0 ArgK protein DUF87 PF01935.12 EMR67059.1 - 0.074 12.8 0.2 14 5.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_13 PF13166.1 EMR67059.1 - 5.1 5.4 7.5 7.9 4.7 0.0 3.6 4 0 0 4 4 4 0 AAA domain UPF0233 PF06781.7 EMR67060.1 - 0.43 10.2 0.0 0.43 10.2 0.0 2.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) Hydrophobin PF01185.13 EMR67061.1 - 4.7e-15 55.7 8.2 6.1e-15 55.4 5.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin BTV_NS2 PF04514.7 EMR67062.1 - 0.88 8.3 24.9 0.84 8.4 12.5 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Sec3_C PF09763.4 EMR67063.1 - 2.8e-202 673.6 5.5 3.5e-189 630.3 1.6 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec3 Sec3_C_2 PF15278.1 EMR67063.1 - 0.017 15.2 0.5 3 8.0 0.0 3.3 3 0 0 3 3 3 0 Sec3 exocyst complex subunit FAD_binding_4 PF01565.18 EMR67064.1 - 1.1e-21 76.7 0.9 1.9e-21 76.0 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR67064.1 - 0.044 13.6 0.2 0.092 12.6 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like HOK_GEF PF01848.11 EMR67064.1 - 0.045 13.0 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Hok/gef family DLH PF01738.13 EMR67064.1 - 0.081 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family MFS_1 PF07690.11 EMR67065.1 - 5.9e-31 107.4 23.3 1.6e-30 105.9 16.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EMR67065.1 - 0.019 14.7 1.4 0.23 11.2 0.6 2.4 2 0 0 2 2 2 0 MFS_1 like family Formyl_trans_N PF00551.14 EMR67066.1 - 4.8e-22 78.3 0.0 7.7e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase DUF3407 PF11887.3 EMR67066.1 - 0.082 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) Fapy_DNA_glyco PF01149.19 EMR67067.1 - 3.8e-26 91.7 0.0 6.8e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EMR67067.1 - 1.7e-20 72.5 0.0 3.7e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EMR67067.1 - 0.00059 18.4 2.2 0.046 12.2 0.0 2.9 2 1 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) Tannase PF07519.6 EMR67068.1 - 1.8e-118 396.2 1.8 2.4e-118 395.8 1.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EMR67068.1 - 0.0046 16.7 0.0 0.05 13.3 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR67068.1 - 0.032 13.4 0.0 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ribosomal_S14 PF00253.16 EMR67068.1 - 0.11 11.9 0.1 0.36 10.2 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e Pribosyl_synth PF14572.1 EMR67069.1 - 5.4e-44 150.1 1.1 1.1e-37 129.6 0.2 2.1 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EMR67069.1 - 9.8e-13 47.9 0.1 1.9e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran_N PF13793.1 EMR67069.1 - 5.9e-06 26.0 0.0 4.8e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase PEX11 PF05648.9 EMR67070.1 - 1e-71 240.7 0.3 1.2e-71 240.5 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) RE_XamI PF09572.5 EMR67070.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 XamI restriction endonuclease FBPase PF00316.15 EMR67071.1 - 6e-125 416.3 0.0 6.8e-125 416.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Cwf_Cwc_15 PF04889.7 EMR67072.1 - 1.8e-88 296.3 20.4 2e-88 296.2 14.1 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 EMR67072.1 - 0.097 11.9 22.2 0.13 11.5 15.4 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EMR67072.1 - 0.15 9.9 23.3 0.18 9.7 16.1 1.1 1 0 0 1 1 1 0 Nop14-like family FAM91_C PF14648.1 EMR67072.1 - 0.17 10.6 0.6 0.2 10.4 0.4 1.1 1 0 0 1 1 1 0 FAM91 C-terminus Glypican PF01153.14 EMR67072.1 - 0.78 8.2 5.6 0.99 7.9 3.9 1.2 1 0 0 1 1 1 0 Glypican Daxx PF03344.10 EMR67072.1 - 1.9 6.8 22.2 2.5 6.5 15.4 1.2 1 0 0 1 1 1 0 Daxx Family IncA PF04156.9 EMR67072.1 - 4.7 6.7 7.1 7.5 6.0 5.0 1.3 1 0 0 1 1 1 0 IncA protein PPP4R2 PF09184.6 EMR67072.1 - 6 6.3 22.3 8.8 5.7 15.4 1.2 1 0 0 1 1 1 0 PPP4R2 Arf PF00025.16 EMR67073.1 - 6.7e-40 136.1 0.2 1.9e-25 89.1 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EMR67073.1 - 1.4e-11 43.7 0.0 2.7e-07 29.6 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EMR67073.1 - 2.8e-08 33.3 0.0 0.00063 19.1 0.0 2.1 2 0 0 2 2 2 2 Ras family Gtr1_RagA PF04670.7 EMR67073.1 - 1.6e-07 30.6 0.0 1.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EMR67073.1 - 2.2e-07 30.2 0.0 7.2e-05 22.0 0.0 2.1 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Miro PF08477.8 EMR67073.1 - 0.00019 21.9 0.0 0.0012 19.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EMR67073.1 - 0.00034 20.0 0.0 0.00086 18.7 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EMR67073.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Lipase_GDSL_2 PF13472.1 EMR67075.1 - 4e-15 56.3 0.5 3.6e-14 53.2 0.1 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family SBDS_C PF09377.5 EMR67076.1 - 1.6e-52 176.4 0.5 2.7e-52 175.7 0.4 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EMR67076.1 - 3e-29 100.6 0.0 5.6e-29 99.7 0.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF3050 PF11251.3 EMR67077.1 - 0.17 11.1 0.6 0.87 8.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3050) DUF2422 PF10337.4 EMR67077.1 - 0.17 10.6 0.0 0.3 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) PAT1 PF09770.4 EMR67077.1 - 5.1 5.2 8.7 8 4.5 6.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PBP PF01161.15 EMR67079.1 - 1.4e-22 80.0 0.0 2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pkinase PF00069.20 EMR67082.1 - 3.6e-08 32.8 0.0 8.5e-05 21.8 0.0 2.9 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR67082.1 - 3.8e-05 22.8 0.0 1.1 8.2 0.0 3.2 2 1 1 3 3 3 3 Protein tyrosine kinase Ribosomal_S13 PF00416.17 EMR67083.1 - 9e-41 138.6 1.7 1.1e-40 138.3 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EMR67083.1 - 0.0063 15.1 0.0 0.0064 15.0 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.3 EMR67083.1 - 0.1 12.7 0.2 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) PP28 PF10252.4 EMR67083.1 - 0.1 12.5 0.6 0.22 11.5 0.4 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Peptidase_S10 PF00450.17 EMR67084.1 - 4e-133 444.6 4.1 4.9e-133 444.3 2.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EMR67084.1 - 2.1e-05 24.4 0.0 0.00021 21.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Carbpep_Y_N PF05388.6 EMR67084.1 - 0.0043 17.1 0.0 0.0082 16.2 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Cas1_AcylT PF07779.7 EMR67085.1 - 5.8e-34 117.3 0.0 1.2e-23 83.3 0.0 2.4 2 0 0 2 2 2 2 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 EMR67085.1 - 9.8e-14 51.7 0.0 1.7e-13 51.0 0.0 1.4 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Peptidase_S10 PF00450.17 EMR67086.1 - 3.8e-85 286.5 0.6 4.7e-85 286.2 0.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ribonuclease PF00545.15 EMR67087.1 - 1.4e-17 63.5 0.1 2.2e-17 62.8 0.1 1.3 1 1 0 1 1 1 1 ribonuclease MtrE PF04206.7 EMR67087.1 - 0.047 12.7 0.1 0.06 12.3 0.1 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E HpcH_HpaI PF03328.9 EMR67088.1 - 8.4e-36 122.9 0.0 1e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 EMR67088.1 - 0.099 11.8 0.5 14 4.7 0.0 2.9 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase DENN PF02141.16 EMR67089.1 - 2.6e-39 134.8 0.0 4.3e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain Elongin_A PF06881.6 EMR67089.1 - 0.003 17.9 1.4 0.003 17.9 1.0 2.6 3 0 0 3 3 3 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2570 PF10828.3 EMR67089.1 - 0.29 10.7 7.2 0.33 10.5 3.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Pkinase PF00069.20 EMR67090.1 - 3.2e-05 23.2 0.0 0.017 14.2 0.0 2.8 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR67090.1 - 0.00016 20.8 0.0 0.063 12.3 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase PBP1_TM PF14812.1 EMR67090.1 - 1.2 9.4 8.4 0.22 11.8 1.1 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal cobW PF02492.14 EMR67092.1 - 8.1e-37 126.3 0.0 1.1e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EMR67092.1 - 0.0056 16.4 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain MobB PF03205.9 EMR67092.1 - 0.0056 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.9 EMR67092.1 - 0.0078 15.9 0.0 0.076 12.7 0.0 2.6 2 1 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain Viral_helicase1 PF01443.13 EMR67092.1 - 0.026 14.0 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EMR67092.1 - 0.043 12.7 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 EMR67092.1 - 0.058 12.8 0.0 0.25 10.7 0.0 1.8 1 1 1 2 2 2 0 AAA-like domain AAA_18 PF13238.1 EMR67092.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EMR67092.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMR67092.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF2796 PF10986.3 EMR67093.1 - 0.026 14.4 2.5 0.031 14.2 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) BUD22 PF09073.5 EMR67093.1 - 0.056 12.5 13.1 0.053 12.5 9.1 1.1 1 0 0 1 1 1 0 BUD22 DDRGK PF09756.4 EMR67093.1 - 0.085 12.2 9.6 0.12 11.7 6.7 1.2 1 0 0 1 1 1 0 DDRGK domain Thg1C PF14413.1 EMR67093.1 - 0.087 12.5 1.6 0.15 11.7 1.1 1.3 1 0 0 1 1 1 0 Thg1 C terminal domain RRN3 PF05327.6 EMR67093.1 - 0.094 10.8 9.0 0.11 10.5 6.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.7 EMR67093.1 - 0.18 11.0 21.1 0.17 11.1 14.7 1.1 1 0 0 1 1 1 0 SDA1 DUF2722 PF10846.3 EMR67093.1 - 0.29 10.1 4.4 0.3 10.0 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Daxx PF03344.10 EMR67093.1 - 0.39 9.1 24.0 0.45 8.9 16.6 1.1 1 0 0 1 1 1 0 Daxx Family Mpp10 PF04006.7 EMR67093.1 - 0.4 8.9 19.1 0.39 9.0 13.3 1.1 1 0 0 1 1 1 0 Mpp10 protein HSP90 PF00183.13 EMR67093.1 - 0.66 8.3 16.0 0.74 8.1 11.1 1.1 1 0 0 1 1 1 0 Hsp90 protein eIF-3c_N PF05470.7 EMR67093.1 - 0.68 7.9 5.7 0.66 7.9 4.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ycf1 PF05758.7 EMR67093.1 - 0.7 7.5 3.9 0.62 7.7 2.7 1.0 1 0 0 1 1 1 0 Ycf1 Rhabdo_ncap PF00945.13 EMR67093.1 - 0.73 8.3 11.6 1 7.9 8.0 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Pox_Ag35 PF03286.9 EMR67093.1 - 0.77 9.2 10.1 1 8.8 7.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 EMR67093.1 - 1.4 6.8 17.7 2 6.3 12.2 1.2 1 0 0 1 1 1 0 CDC45-like protein ABC_trans_N PF14510.1 EMR67093.1 - 1.9 8.6 4.5 54 3.9 0.0 2.2 2 0 0 2 2 2 0 ABC-transporter extracellular N-terminal DUF2457 PF10446.4 EMR67093.1 - 2.1 7.0 31.0 2.6 6.6 21.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DDHD PF02862.12 EMR67093.1 - 3.8 7.2 5.0 5 6.8 3.5 1.1 1 0 0 1 1 1 0 DDHD domain Sigma70_ner PF04546.8 EMR67093.1 - 4.1 6.9 21.1 6.8 6.2 14.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.7 EMR67093.1 - 7.2 6.2 18.1 12 5.5 12.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Prothymosin PF03247.9 EMR67093.1 - 8.2 6.6 39.1 18 5.5 27.1 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family zf-CCHC PF00098.18 EMR67096.1 - 8.8e-12 44.3 10.2 8.9e-06 25.3 0.5 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EMR67096.1 - 8.6e-09 34.9 0.2 1.6e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EMR67096.1 - 4.1e-07 29.6 8.2 0.0013 18.4 2.4 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EMR67096.1 - 1.1e-05 24.9 0.2 2.8e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 EMR67096.1 - 0.00028 20.4 8.6 0.072 12.7 0.4 2.7 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EMR67096.1 - 0.0012 18.4 6.4 0.28 10.8 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle ECH PF00378.15 EMR67097.1 - 6.9e-23 81.0 0.0 9e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EMR67097.1 - 0.073 12.8 0.0 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 Ras PF00071.17 EMR67098.1 - 6.2e-35 119.9 0.0 8.3e-35 119.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR67098.1 - 2.8e-15 56.8 0.0 5.1e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMR67098.1 - 0.0016 17.6 0.0 0.003 16.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMR67098.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TRAPP PF04051.11 EMR67099.1 - 4.4e-29 100.9 0.0 5.3e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF2763 PF10961.3 EMR67099.1 - 2.9 8.3 7.7 4.8 7.6 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) DUF2423 PF10338.4 EMR67100.1 - 3.7e-17 62.0 6.2 3.7e-17 62.0 4.3 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF2423) TRAP_alpha PF03896.11 EMR67100.1 - 0.32 9.9 2.6 0.41 9.6 1.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PINIT PF14324.1 EMR67101.1 - 1.7e-24 86.5 0.0 5.5e-24 84.8 0.0 1.9 2 0 0 2 2 2 1 PINIT domain Alpha_L_fucos PF01120.12 EMR67102.1 - 1.1e-63 215.2 9.5 3.7e-34 118.1 6.7 2.1 1 1 1 2 2 2 2 Alpha-L-fucosidase DUF2272 PF10030.4 EMR67102.1 - 0.055 12.9 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2272) DUF1996 PF09362.5 EMR67103.1 - 2.7e-91 305.4 0.9 3.7e-91 304.9 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) F-box-like PF12937.2 EMR67104.1 - 0.00011 21.8 0.4 0.00044 19.9 0.0 2.2 2 0 0 2 2 2 1 F-box-like HhH-GPD PF00730.20 EMR67105.1 - 3e-20 72.4 0.0 8.6e-20 71.0 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 EMR67105.1 - 1.5e-15 56.6 0.0 4.3e-15 55.1 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.18 EMR67105.1 - 0.00048 19.6 0.2 0.0014 18.1 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EMR67105.1 - 0.018 15.2 0.0 3.6 7.8 0.0 3.3 3 1 0 3 3 3 0 Helix-hairpin-helix domain Glyco_hydro_92 PF07971.7 EMR67106.1 - 1.8e-169 564.6 0.2 2.1e-169 564.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Sec23_trunk PF04811.10 EMR67107.1 - 3.6e-51 173.8 0.0 1e-50 172.3 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMR67107.1 - 1.2e-23 82.4 0.0 2.1e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMR67107.1 - 8.9e-17 61.3 0.0 1.6e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EMR67107.1 - 3.8e-16 58.3 4.1 3.8e-16 58.3 2.9 2.0 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EMR67107.1 - 4.7e-05 22.9 0.0 0.00013 21.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Glyco_hydro_92 PF07971.7 EMR67108.1 - 2.7e-146 488.1 0.0 3.5e-146 487.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Musclin PF11037.3 EMR67110.1 - 0.07 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle Flagellin_N PF00669.15 EMR67110.1 - 4.8 6.9 7.7 0.33 10.7 0.6 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region zf-H2C2 PF09337.5 EMR67113.1 - 1e-15 56.8 2.7 1.9e-15 55.9 1.8 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 EMR67113.1 - 1e-05 25.4 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EMR67113.1 - 6.2e-05 22.9 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMR67113.1 - 0.00032 20.8 0.0 0.00054 20.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR67113.1 - 0.033 13.9 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.1 EMR67113.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_92 PF07971.7 EMR67114.1 - 1.5e-146 488.9 0.0 1.2e-109 367.3 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 adh_short PF00106.20 EMR67115.1 - 2.4e-15 56.8 0.0 3.7e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR67115.1 - 5.6e-08 32.6 0.0 8.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR67115.1 - 0.00045 19.7 0.0 0.00084 18.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMR67115.1 - 0.0015 18.3 0.0 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMR67115.1 - 0.0055 16.7 0.0 0.0085 16.1 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EMR67115.1 - 0.0089 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EMR67115.1 - 0.025 13.4 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_tran_WecB PF03808.8 EMR67115.1 - 0.089 12.1 0.0 0.85 8.9 0.0 2.1 2 1 1 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family Amidohydro_4 PF13147.1 EMR67117.1 - 3.1e-09 37.2 8.7 3.8e-09 36.9 2.0 3.2 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EMR67117.1 - 9.9e-07 28.7 1.6 1.2e-05 25.1 0.0 3.0 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_3 PF07969.6 EMR67117.1 - 3e-06 26.7 0.0 9.2e-06 25.1 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMR67117.1 - 0.001 18.8 0.0 0.0058 16.4 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase Beta-Casp PF10996.3 EMR67118.1 - 2.4e-26 92.1 0.0 5.7e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Asp PF00026.18 EMR67119.1 - 6.9e-32 110.9 0.6 1e-31 110.4 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMR67119.1 - 0.00064 19.7 1.9 0.0037 17.2 1.3 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal SIR2_2 PF13289.1 EMR67122.1 - 8.9e-20 71.0 0.0 1.5e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 SIR2-like domain CBP4 PF07960.6 EMR67123.1 - 4.7e-37 126.4 0.8 6.1e-37 126.1 0.5 1.0 1 0 0 1 1 1 1 CBP4 ERCC4 PF02732.10 EMR67123.1 - 0.029 14.1 0.3 0.035 13.8 0.2 1.1 1 0 0 1 1 1 0 ERCC4 domain DUF576 PF04507.7 EMR67123.1 - 0.055 12.3 0.1 0.056 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF576 DUF2852 PF11014.3 EMR67123.1 - 0.3 11.0 5.9 0.039 13.8 1.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) RRM_6 PF14259.1 EMR67124.1 - 1.5e-06 28.1 0.0 2.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR67124.1 - 0.024 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.23 EMR67125.1 - 6.9e-13 49.2 0.0 1.4e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 SET domain Aconitase PF00330.15 EMR67126.1 - 5.8e-46 156.9 0.0 3.5e-39 134.5 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMR67126.1 - 2.4e-25 89.1 0.0 5.2e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain SecE PF00584.15 EMR67127.1 - 1.6e-12 46.8 0.0 1.7e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.27 EMR67128.1 - 2.4e-22 77.9 10.4 6.5e-09 35.3 0.5 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EMR67128.1 - 0.00031 19.1 1.6 0.21 9.8 0.0 3.8 3 1 2 5 5 5 2 Cytochrome D1 heme domain BBS2_Mid PF14783.1 EMR67128.1 - 0.03 14.0 0.0 1.3 8.8 0.0 3.1 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 EMR67128.1 - 0.03 13.9 0.2 0.33 10.6 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nucleo_P87 PF07267.6 EMR67128.1 - 9.3 4.7 5.0 16 4.0 3.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Histidinol_dh PF00815.15 EMR67129.1 - 1.2e-179 597.2 4.9 1.6e-179 596.8 3.4 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EMR67129.1 - 9.5e-25 86.0 0.1 2e-24 85.0 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EMR67129.1 - 1.9e-10 40.8 1.2 5.6e-10 39.3 0.1 2.3 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Tannase PF07519.6 EMR67130.1 - 7.5e-106 354.6 0.6 9.1e-106 354.3 0.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EMR67130.1 - 0.00059 19.6 0.1 0.12 12.1 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Enolase_C PF00113.17 EMR67130.1 - 0.2 10.6 1.5 0.27 10.1 0.0 1.7 2 0 0 2 2 2 0 Enolase, C-terminal TIM barrel domain SNARE PF05739.14 EMR67131.1 - 8.7e-10 38.1 6.1 8.7e-10 38.1 4.2 3.2 3 1 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EMR67131.1 - 7e-08 32.5 11.2 5.6e-07 29.6 3.2 2.4 2 0 0 2 2 2 2 Syntaxin DUF4094 PF13334.1 EMR67131.1 - 0.0089 16.3 1.1 6.1 7.3 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) Foamy_virus_ENV PF03408.9 EMR67131.1 - 0.021 12.3 1.4 0.03 11.8 1.0 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein YlqD PF11068.3 EMR67131.1 - 0.024 14.6 1.7 0.024 14.6 1.2 3.1 1 1 1 2 2 1 0 YlqD protein OppC_N PF12911.2 EMR67131.1 - 0.039 13.3 0.2 0.08 12.3 0.1 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PilJ PF13675.1 EMR67131.1 - 0.044 14.0 15.9 2.9 8.2 4.6 3.1 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Allexi_40kDa PF05549.6 EMR67131.1 - 0.066 12.4 6.7 0.11 11.7 0.7 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein WXG100 PF06013.7 EMR67131.1 - 0.12 12.4 12.6 1.2 9.1 1.7 3.4 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Rifin_STEVOR PF02009.11 EMR67131.1 - 0.17 11.5 11.0 0.021 14.4 3.2 2.0 1 1 1 2 2 2 0 Rifin/stevor family Laminin_II PF06009.7 EMR67131.1 - 0.22 11.2 12.5 0.52 10.0 1.3 2.5 2 1 0 2 2 2 0 Laminin Domain II Seryl_tRNA_N PF02403.17 EMR67131.1 - 0.43 10.6 10.0 1 9.3 0.2 3.2 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.4 EMR67131.1 - 0.88 9.7 8.3 1.3 9.1 0.5 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EURL PF06937.6 EMR67131.1 - 1 8.7 11.1 1.5 8.1 7.7 1.2 1 0 0 1 1 1 0 EURL protein FlaC_arch PF05377.6 EMR67131.1 - 1.7 8.6 5.5 18 5.2 0.1 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DASH_Dam1 PF08653.5 EMR67131.1 - 2 8.2 3.8 3.7 7.3 0.2 2.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 AAA_13 PF13166.1 EMR67131.1 - 3.8 5.8 12.3 0.93 7.8 1.9 2.0 1 1 1 2 2 2 0 AAA domain DUF2866 PF11065.3 EMR67131.1 - 3.8 7.4 5.1 0.45 10.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2866) IFT46_B_C PF12317.3 EMR67131.1 - 4 6.7 5.7 2.9 7.2 0.6 2.3 1 1 2 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal Shisa PF13908.1 EMR67132.1 - 0.013 15.6 0.3 0.022 14.9 0.2 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DAP10 PF07213.6 EMR67132.1 - 0.043 13.5 0.6 0.085 12.6 0.4 1.4 1 0 0 1 1 1 0 DAP10 membrane protein Herpes_gE PF02480.11 EMR67132.1 - 0.071 11.3 0.0 0.088 11.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E VSP PF03302.8 EMR67132.1 - 0.16 10.6 1.7 0.21 10.2 1.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein AlaDh_PNT_N PF05222.10 EMR67133.1 - 4.4e-28 97.9 0.0 6.2e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EMR67133.1 - 1.2e-17 64.0 0.0 1.6e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Zn_clus PF00172.13 EMR67134.1 - 3.2e-08 33.3 12.4 5.4e-08 32.6 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.12 EMR67135.1 - 1.9 8.2 13.6 2.7 7.7 9.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Memo PF01875.12 EMR67136.1 - 4.4e-59 199.6 0.0 6.5e-58 195.7 0.0 1.9 1 1 0 1 1 1 1 Memo-like protein RNA_binding PF01877.12 EMR67137.1 - 0.011 15.7 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 RNA binding Cupin_2 PF07883.6 EMR67139.1 - 0.033 13.6 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Cupin domain MFS_1 PF07690.11 EMR67140.1 - 7.9e-33 113.6 25.3 1.2e-32 113.0 17.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF21 PF01595.15 EMR67140.1 - 0.13 11.5 5.2 0.13 11.5 2.0 2.3 1 1 0 1 1 1 0 Domain of unknown function DUF21 Glyco_hydro_88 PF07470.8 EMR67141.1 - 1e-85 287.8 3.3 1.2e-85 287.5 2.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 EMR67141.1 - 0.00036 18.9 0.6 0.00052 18.4 0.4 1.1 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) LANC_like PF05147.8 EMR67141.1 - 0.0097 14.5 0.2 5.4 5.4 0.0 3.3 4 0 0 4 4 4 1 Lanthionine synthetase C-like protein Glyco_hydro_76 PF03663.9 EMR67141.1 - 0.02 14.2 8.7 0.11 11.8 1.6 2.5 1 1 1 2 2 2 0 Glycosyl hydrolase family 76 MiaE PF06175.6 EMR67141.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) IDO PF01231.13 EMR67142.1 - 1.6e-135 451.8 0.0 2e-135 451.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EMR67142.1 - 0.0019 16.8 0.0 1.2 7.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1864) Methyltransf_23 PF13489.1 EMR67143.1 - 1.9e-14 53.7 0.0 2.6e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR67143.1 - 4.3e-09 36.7 0.0 7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR67143.1 - 1.1e-08 35.6 0.0 3.4e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR67143.1 - 1.4e-08 34.5 0.0 3.4e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMR67143.1 - 3.3e-06 26.2 0.0 1.7e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 EMR67143.1 - 7.5e-05 23.1 0.0 0.00021 21.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR67143.1 - 0.0018 18.2 0.0 0.0068 16.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EMR67143.1 - 0.003 16.8 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_8 PF05148.10 EMR67143.1 - 0.004 16.7 0.0 0.0058 16.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_25 PF13649.1 EMR67143.1 - 0.0092 16.3 0.0 0.024 14.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMR67143.1 - 0.013 15.4 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase PrmA PF06325.8 EMR67143.1 - 0.016 14.3 0.0 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.8 EMR67143.1 - 0.035 13.3 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.9 EMR67143.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.15 EMR67143.1 - 0.17 10.9 0.0 0.37 9.8 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase GidB PF02527.10 EMR67143.1 - 0.17 11.0 0.0 2.1 7.4 0.0 2.1 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G QRPTase_C PF01729.14 EMR67144.1 - 1.6e-54 183.9 0.1 2e-54 183.6 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EMR67144.1 - 1.2e-21 76.3 0.0 4.7e-21 74.3 0.0 2.1 3 1 0 3 3 3 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.17 EMR67144.1 - 0.036 13.6 0.1 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Ubie_methyltran PF01209.13 EMR67146.1 - 7.2e-59 198.7 0.0 8.5e-59 198.4 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EMR67146.1 - 2.9e-09 37.2 0.0 4.5e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR67146.1 - 1e-07 32.2 0.0 1.7e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR67146.1 - 1.6e-07 31.0 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR67146.1 - 3.1e-06 26.9 0.0 4.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR67146.1 - 3.4e-05 24.1 0.0 6.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR67146.1 - 0.00037 21.0 0.1 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR67146.1 - 0.0029 17.6 0.6 0.07 13.1 0.4 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR67146.1 - 0.13 11.6 0.1 0.38 10.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_8 PF05148.10 EMR67146.1 - 0.14 11.7 0.0 1.5 8.3 0.0 2.3 3 0 0 3 3 3 0 Hypothetical methyltransferase NmrA PF05368.8 EMR67147.1 - 1.8e-11 43.7 0.0 3.2e-10 39.6 0.0 2.5 2 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EMR67147.1 - 2.8e-08 33.9 1.0 6.2e-08 32.8 0.2 1.8 2 0 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EMR67147.1 - 0.0015 18.8 0.0 0.0032 17.7 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EMR67147.1 - 0.032 12.9 0.0 0.055 12.1 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMR67147.1 - 0.059 13.2 0.5 0.71 9.7 0.0 2.5 3 0 0 3 3 3 0 short chain dehydrogenase ATP-grasp_3 PF02655.9 EMR67149.1 - 1.1e-09 38.3 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EMR67149.1 - 6.1e-06 26.0 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMR67149.1 - 0.00024 20.5 0.0 0.00047 19.6 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EMR67149.1 - 0.011 15.2 0.0 0.3 10.5 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATPgrasp_Ter PF15632.1 EMR67149.1 - 0.1 11.3 0.0 0.2 10.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon LtrA PF06772.6 EMR67150.1 - 2.1e-09 36.7 3.6 2.1e-09 36.7 2.5 3.0 2 1 1 3 3 3 2 Bacterial low temperature requirement A protein (LtrA) DUF3112 PF11309.3 EMR67150.1 - 0.35 10.6 5.9 0.15 11.8 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) PNP_UDP_1 PF01048.15 EMR67151.1 - 6.4e-10 38.3 0.1 3.2e-09 36.1 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily GST_N_3 PF13417.1 EMR67152.1 - 1.8e-17 63.2 0.0 4.1e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMR67152.1 - 1.5e-13 50.5 0.0 2.8e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMR67152.1 - 4.3e-10 39.6 0.0 7.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EMR67152.1 - 1.4e-05 24.9 0.0 0.00078 19.3 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin GST_C_2 PF13410.1 EMR67152.1 - 0.0012 18.6 0.0 0.0035 17.1 0.0 1.6 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMR67152.1 - 0.0091 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 EMR67153.1 - 6.4e-13 48.1 33.2 2.9e-08 32.8 6.3 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily CFEM PF05730.6 EMR67154.1 - 2e-08 33.9 7.5 3.2e-08 33.2 5.2 1.3 1 0 0 1 1 1 1 CFEM domain RFC1 PF08519.7 EMR67155.1 - 2.2e-56 189.9 0.0 2.2e-56 189.9 0.0 2.2 3 0 0 3 3 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EMR67155.1 - 2.9e-14 52.9 0.0 6.2e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EMR67155.1 - 5.9e-09 36.2 0.0 1.7e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR67155.1 - 1.5e-06 28.3 0.2 5.6e-06 26.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EMR67155.1 - 9.2e-05 23.2 0.0 9.2e-05 23.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.10 EMR67155.1 - 0.0005 18.8 0.0 0.00092 18.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EMR67155.1 - 0.0005 19.7 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EMR67155.1 - 0.00066 19.9 0.1 0.00066 19.9 0.1 3.1 3 0 0 3 3 2 1 AAA domain DNA_pol3_delta PF06144.8 EMR67155.1 - 0.00087 18.8 0.0 0.0046 16.4 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EMR67155.1 - 0.0014 18.4 0.0 0.004 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR67155.1 - 0.0064 16.4 0.3 0.045 13.7 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain NTPase_1 PF03266.10 EMR67155.1 - 0.041 13.6 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.1 EMR67155.1 - 0.052 13.4 0.0 0.19 11.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EMR67155.1 - 0.081 12.5 0.0 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Glyco_hydro_18 PF00704.23 EMR67156.1 - 3.2e-40 138.6 0.3 4.1e-40 138.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HCNGP PF07818.8 EMR67156.1 - 0.12 12.3 0.1 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 HCNGP-like protein Gly-zipper_Omp PF13488.1 EMR67156.1 - 0.39 10.4 2.6 2.6 7.7 0.1 2.4 2 0 0 2 2 2 0 Glycine zipper DUF1996 PF09362.5 EMR67157.1 - 4.9e-84 281.6 4.2 6.9e-84 281.1 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF721 PF05258.7 EMR67159.1 - 0.034 14.3 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF721) Glyco_hydro_88 PF07470.8 EMR67160.1 - 3.4e-42 144.6 3.1 4.1e-42 144.4 2.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Rgp1 PF08737.5 EMR67161.1 - 4.4e-120 401.5 0.0 8.8e-119 397.2 0.0 2.5 3 0 0 3 3 3 1 Rgp1 Nucleoplasmin PF03066.10 EMR67161.1 - 0.0012 18.3 0.8 0.0021 17.5 0.6 1.3 1 0 0 1 1 1 1 Nucleoplasmin Arrestin_N PF00339.24 EMR67161.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain API5 PF05918.6 EMR67161.1 - 0.17 10.3 3.9 0.24 9.8 2.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2457 PF10446.4 EMR67161.1 - 0.45 9.1 12.6 0.71 8.5 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 EMR67161.1 - 1.3 8.5 4.8 2.2 7.8 3.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 EMR67161.1 - 1.7 7.8 8.0 2.6 7.2 5.6 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 EMR67161.1 - 2.2 8.5 12.8 2.1 8.6 6.9 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BAF1_ABF1 PF04684.8 EMR67161.1 - 2.5 6.8 8.9 3.8 6.2 6.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4611 PF15387.1 EMR67161.1 - 4.9 7.3 9.3 11 6.1 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.6 EMR67161.1 - 5.4 6.8 6.6 7.2 6.3 4.0 1.5 2 0 0 2 2 2 0 RXT2-like, N-terminal DASH_Dad3 PF08656.5 EMR67162.1 - 1.3e-29 101.7 1.1 1.5e-29 101.4 0.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 VBS PF08913.5 EMR67162.1 - 0.12 12.6 0.0 2 8.6 0.0 1.9 1 1 1 2 2 2 0 Vinculin Binding Site Ribosomal_S5_C PF03719.10 EMR67163.1 - 1.9e-18 65.5 0.1 3.5e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EMR67163.1 - 2e-07 30.6 0.1 4.4e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain CorA PF01544.13 EMR67164.1 - 0.00025 20.1 0.0 0.00054 19.0 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Abhydrolase_6 PF12697.2 EMR67165.1 - 2.9e-21 76.4 0.0 9.9e-13 48.4 0.0 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR67165.1 - 3.3e-13 49.7 0.1 4.6e-08 32.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR67165.1 - 1.4e-09 37.8 0.0 2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMR67165.1 - 0.03 14.1 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S15 PF02129.13 EMR67165.1 - 0.13 11.6 0.2 0.36 10.2 0.1 1.7 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF843 PF05814.6 EMR67166.1 - 0.0037 17.0 0.1 0.0048 16.6 0.1 1.1 1 0 0 1 1 1 1 Baculovirus protein of unknown function (DUF843) UPF0542 PF15086.1 EMR67166.1 - 0.0069 16.0 0.0 0.0083 15.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 DcuC PF03606.10 EMR67166.1 - 0.012 13.8 0.4 0.28 9.3 0.0 1.9 1 1 1 2 2 2 0 C4-dicarboxylate anaerobic carrier DUF3609 PF12259.3 EMR67166.1 - 0.032 12.8 0.0 0.035 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Baculo_11_kDa PF06143.6 EMR67166.1 - 0.041 13.2 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family OAD_gamma PF04277.8 EMR67166.1 - 0.042 14.2 0.0 0.071 13.4 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TLC PF03219.9 EMR67166.1 - 0.046 12.2 0.0 0.047 12.1 0.0 1.0 1 0 0 1 1 1 0 TLC ATP/ADP transporter BatD PF13584.1 EMR67166.1 - 0.061 11.9 0.0 0.068 11.7 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance Vpu PF00558.14 EMR67166.1 - 0.063 12.8 0.2 0.084 12.4 0.1 1.2 1 0 0 1 1 1 0 Vpu protein Chordopox_A13L PF05961.6 EMR67166.1 - 0.07 13.0 0.2 0.093 12.6 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus A13L protein CLASP_N PF12348.3 EMR67167.1 - 1.2e-116 387.9 2.0 7e-85 284.0 0.0 4.2 4 1 1 5 5 5 3 CLASP N terminal HEAT PF02985.17 EMR67167.1 - 0.0014 18.5 0.3 23 5.4 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat CDC45 PF02724.9 EMR67168.1 - 7.8 4.3 7.2 9.9 4.0 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_92 PF07971.7 EMR67170.1 - 6.3e-86 289.0 0.0 9.1e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Acetyltransf_1 PF00583.19 EMR67170.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Iso_dh PF00180.15 EMR67171.1 - 4.4e-98 328.4 0.0 5.4e-98 328.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IclR PF01614.13 EMR67171.1 - 0.02 14.5 0.2 0.044 13.4 0.1 1.5 1 0 0 1 1 1 0 Bacterial transcriptional regulator Sec5 PF15469.1 EMR67172.1 - 2.1e-26 92.7 0.0 2.4e-19 69.7 0.0 3.1 1 1 1 2 2 2 2 Exocyst complex component Sec5 BSP PF04450.7 EMR67173.1 - 7.6e-78 260.6 0.0 9.3e-78 260.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EMR67173.1 - 8.2e-07 29.1 0.1 6.1e-06 26.2 0.1 2.1 1 1 0 1 1 1 1 Peptidase MA superfamily Pex14_N PF04695.8 EMR67173.1 - 0.095 12.7 2.2 0.15 12.1 1.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Menin PF05053.8 EMR67173.1 - 6.5 4.7 5.6 8.2 4.4 3.9 1.1 1 0 0 1 1 1 0 Menin Acetyltransf_10 PF13673.1 EMR67174.1 - 1.7e-05 24.8 0.1 0.068 13.3 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR67174.1 - 0.00012 22.0 0.0 0.00032 20.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR67174.1 - 0.001 19.1 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1183 PF06682.7 EMR67174.1 - 1.5 8.3 14.0 0.82 9.2 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) rRNA_processing PF08524.6 EMR67175.1 - 0.00041 20.1 12.9 0.00041 20.1 8.9 2.2 1 1 1 2 2 2 1 rRNA processing Nop25 PF09805.4 EMR67175.1 - 0.00049 20.1 13.7 0.00049 20.1 9.5 2.4 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) Nop53 PF07767.6 EMR67175.1 - 0.099 11.6 26.2 0.18 10.7 18.2 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RhoGAP PF00620.22 EMR67176.1 - 2.2e-46 157.2 1.1 7.9e-46 155.4 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain ARD PF03079.9 EMR67176.1 - 0.7 9.8 4.5 0.2 11.6 0.4 2.0 2 0 0 2 2 2 0 ARD/ARD' family DUF948 PF06103.6 EMR67176.1 - 6.3 6.7 9.4 11 5.9 0.4 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) zf-BED PF02892.10 EMR67177.1 - 0.00018 21.2 0.3 0.00033 20.3 0.2 1.4 1 0 0 1 1 1 1 BED zinc finger Zn-ribbon_8 PF09723.5 EMR67177.1 - 0.068 13.1 0.2 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Cu-oxidase_3 PF07732.10 EMR67178.1 - 2.5e-36 123.9 7.0 3.7e-28 97.6 2.7 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EMR67178.1 - 1.1e-17 64.3 0.0 2.4e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase DUF1295 PF06966.7 EMR67179.1 - 3.6e-24 85.3 0.0 4.9e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EMR67179.1 - 0.0019 18.3 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EMR67179.1 - 0.0089 16.1 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase Adeno_PIX PF03955.9 EMR67179.1 - 0.11 13.0 0.3 38 4.8 0.0 3.9 3 2 2 5 5 5 0 Adenovirus hexon-associated protein (IX) Steroid_dh PF02544.11 EMR67179.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.12 EMR67179.1 - 0.21 10.1 0.0 0.31 9.5 0.0 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DNA_methylase PF00145.12 EMR67180.1 - 9.2e-34 117.0 0.0 1.4e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EMR67180.1 - 0.021 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 BAH domain Ank_2 PF12796.2 EMR67181.1 - 1.6e-19 70.0 2.3 2.3e-09 37.4 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMR67181.1 - 6.9e-17 61.0 1.3 9.8e-09 35.1 0.0 4.2 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EMR67181.1 - 3.4e-15 54.9 0.4 0.0015 18.2 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EMR67181.1 - 8.6e-12 45.2 0.3 3.4e-08 33.7 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR67181.1 - 6.3e-09 35.2 0.5 0.5 10.7 0.0 6.1 7 0 0 7 7 7 2 Ankyrin repeat zf-C4pol PF14260.1 EMR67181.1 - 0.0097 15.8 1.3 3.4 7.7 0.1 2.5 2 0 0 2 2 2 2 C4-type zinc-finger of DNA polymerase delta VBS PF08913.5 EMR67181.1 - 0.063 13.5 0.2 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 Vinculin Binding Site DivIVA PF05103.8 EMR67181.1 - 0.61 10.1 4.1 0.3 11.1 0.3 2.4 3 0 0 3 3 3 0 DivIVA protein CFEM PF05730.6 EMR67182.1 - 6.5e-09 35.4 5.3 9.4e-09 34.9 3.6 1.4 1 0 0 1 1 1 1 CFEM domain Isochorismatase PF00857.15 EMR67183.1 - 5.2e-27 94.8 0.1 1.1e-26 93.8 0.1 1.5 1 1 0 1 1 1 1 Isochorismatase family ACC_central PF08326.7 EMR67184.1 - 1.7e-247 823.0 0.0 2.2e-247 822.7 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EMR67184.1 - 5.1e-171 569.3 0.0 6.6e-171 568.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EMR67184.1 - 1.6e-51 174.5 0.0 3e-51 173.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EMR67184.1 - 5.5e-24 84.4 0.1 1.5e-23 83.0 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EMR67184.1 - 2e-21 75.9 0.0 4.4e-20 71.6 0.0 2.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EMR67184.1 - 1.7e-17 62.8 0.4 4.1e-17 61.5 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EMR67184.1 - 2.8e-09 36.9 0.0 7.6e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMR67184.1 - 4.6e-06 25.5 0.0 0.025 13.3 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EMR67184.1 - 0.013 14.8 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EMR67184.1 - 0.048 13.3 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EMR67184.1 - 0.11 12.4 0.0 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain AAA PF00004.24 EMR67187.1 - 2.8e-14 53.4 0.0 7.9e-14 51.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR67187.1 - 0.0054 16.8 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EMR67187.1 - 0.024 14.8 0.0 0.069 13.3 0.0 1.8 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 EMR67187.1 - 0.067 12.8 0.0 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 EMR67187.1 - 0.17 11.6 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain SelR PF01641.13 EMR67188.1 - 2.2e-51 172.7 0.1 2.5e-51 172.5 0.1 1.0 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 EMR67188.1 - 0.033 14.0 2.6 3.4 7.5 0.1 2.4 2 1 0 2 2 2 0 Double zinc ribbon DUF2296 PF10058.4 EMR67188.1 - 0.072 12.8 0.3 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) TF_Zn_Ribbon PF08271.7 EMR67188.1 - 0.073 12.4 1.1 0.28 10.5 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding Ribosomal_S27e PF01667.12 EMR67188.1 - 0.12 11.9 0.3 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S27 RRN7 PF11781.3 EMR67188.1 - 0.25 10.8 3.2 3.6 7.1 0.8 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-Mss51 PF13824.1 EMR67188.1 - 0.51 10.2 2.9 41 4.1 0.1 3.2 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 PP2C PF00481.16 EMR67189.1 - 2.8e-33 115.3 0.0 9.5e-28 97.2 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EMR67189.1 - 0.0054 16.1 0.0 0.013 14.8 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C DUF382 PF04037.8 EMR67190.1 - 2.3e-62 208.5 1.5 2.3e-62 208.5 1.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EMR67190.1 - 7.1e-20 70.1 7.0 1.7e-19 68.9 4.9 1.7 1 0 0 1 1 1 1 PSP Nucleoplasmin PF03066.10 EMR67190.1 - 4 6.9 16.8 1.2 8.6 5.6 2.7 2 0 0 2 2 2 0 Nucleoplasmin Snf7 PF03357.16 EMR67192.1 - 3.8e-22 78.4 0.7 3.8e-22 78.4 0.5 1.9 2 0 0 2 2 2 1 Snf7 GAS PF13851.1 EMR67192.1 - 1.8 7.7 5.1 0.18 11.0 0.4 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2870 PF11069.3 EMR67192.1 - 2 8.4 5.3 2.8 8.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Ribosomal_60s PF00428.14 EMR67192.1 - 6.7 7.1 12.2 0.43 11.0 4.4 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4470 PF14737.1 EMR67193.1 - 1.4e-16 60.0 0.0 3e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) ATP-synt_ab PF00006.20 EMR67194.1 - 5.9e-62 208.9 0.0 8.9e-62 208.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMR67194.1 - 3.3e-24 85.5 0.2 6.1e-24 84.6 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMR67194.1 - 4.1e-24 84.5 0.7 1.1e-23 83.1 0.2 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.24 EMR67194.1 - 0.0059 16.7 0.1 0.43 10.7 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EMR67194.1 - 0.0089 15.4 0.1 0.048 13.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EMR67194.1 - 0.01 15.5 0.1 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EMR67194.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 EMR67194.1 - 0.017 14.3 0.1 0.03 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KaiC PF06745.8 EMR67194.1 - 0.019 14.0 0.1 0.032 13.3 0.1 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EMR67194.1 - 0.027 14.1 0.1 0.069 12.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EMR67194.1 - 0.048 13.6 0.3 0.31 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EMR67194.1 - 0.052 13.6 0.1 0.18 11.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EMR67194.1 - 0.066 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EMR67194.1 - 0.1 11.4 0.8 0.61 8.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain DUF1675 PF07897.6 EMR67195.1 - 0.44 10.3 7.7 0.033 14.0 1.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) TPT PF03151.11 EMR67196.1 - 3.7e-39 133.8 1.3 7.8e-39 132.7 0.9 1.5 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.6 EMR67196.1 - 1.2e-06 27.6 10.5 4.5e-06 25.8 7.3 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EMR67196.1 - 0.0042 17.1 27.7 0.0079 16.2 3.5 3.1 3 1 0 3 3 3 2 EamA-like transporter family M-factor PF03855.8 EMR67196.1 - 0.061 13.3 0.3 0.16 11.9 0.2 1.7 1 0 0 1 1 1 0 M-factor Multi_Drug_Res PF00893.14 EMR67196.1 - 7 7.1 12.4 5.1 7.6 0.9 3.8 4 0 0 4 4 4 0 Small Multidrug Resistance protein CS PF04969.11 EMR67197.1 - 1.7e-09 38.1 0.0 2.5e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 CS domain Flavin_Reduct PF01613.13 EMR67198.1 - 5.1e-15 55.6 0.0 9.5e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain VirionAssem_T7 PF11653.3 EMR67198.1 - 0.12 13.1 4.0 2 9.2 0.3 2.3 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein Oxidored_FMN PF00724.15 EMR67199.1 - 2.2e-37 128.8 0.0 3.4e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family adh_short PF00106.20 EMR67199.1 - 1e-17 64.5 0.0 6.8e-17 61.8 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR67199.1 - 5.5e-08 32.8 0.0 1.7e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR67199.1 - 0.00075 19.2 0.0 0.0061 16.2 0.0 2.5 2 1 1 3 3 3 1 KR domain DUF1776 PF08643.5 EMR67199.1 - 0.055 12.6 0.0 1.6 7.8 0.0 2.5 3 0 0 3 3 3 0 Fungal family of unknown function (DUF1776) SCIMP PF15050.1 EMR67200.1 - 0.007 16.2 0.2 0.017 14.9 0.1 1.6 1 1 0 1 1 1 1 SCIMP protein DUF605 PF04652.11 EMR67200.1 - 1.9 7.7 8.6 2.3 7.5 5.9 1.1 1 0 0 1 1 1 0 Vta1 like Sugar_tr PF00083.19 EMR67201.1 - 3.6e-70 236.7 18.4 1e-69 235.2 12.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR67201.1 - 1e-10 40.8 35.0 1.3e-05 24.0 9.3 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EMR67201.1 - 0.00018 20.0 20.1 0.0058 15.0 3.9 3.9 3 1 0 4 4 4 2 MFS/sugar transport protein SIR2 PF02146.12 EMR67202.1 - 6e-24 84.7 0.1 1.7e-14 53.9 0.1 2.8 2 1 0 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 EMR67202.1 - 0.087 12.5 0.1 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain adh_short PF00106.20 EMR67204.1 - 7.7e-13 48.7 0.6 1.5e-12 47.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR67204.1 - 1.7e-05 24.5 0.3 1.7e-05 24.5 0.2 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMR67204.1 - 0.00044 20.1 0.1 0.00079 19.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EMR67204.1 - 0.042 13.9 0.1 0.068 13.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EMR67204.1 - 0.052 13.3 1.4 0.34 10.7 0.1 2.1 1 1 1 2 2 2 0 ThiF family FAD_binding_3 PF01494.14 EMR67205.1 - 9.8e-11 41.2 1.5 1.3e-06 27.7 0.1 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMR67205.1 - 5.6e-06 26.2 0.4 1.8e-05 24.6 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR67205.1 - 1.2e-05 24.3 0.1 0.0026 16.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR67205.1 - 3.7e-05 22.7 0.1 6.2e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMR67205.1 - 5.8e-05 21.7 0.1 0.0041 15.6 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EMR67205.1 - 0.00023 20.1 0.0 0.0005 19.0 0.0 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EMR67205.1 - 0.00034 20.5 1.0 0.0013 18.6 0.7 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR67205.1 - 0.00092 19.5 0.4 0.022 15.1 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR67205.1 - 0.0015 18.6 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMR67205.1 - 0.011 14.7 0.7 0.016 14.2 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMR67205.1 - 0.033 13.1 0.0 0.85 8.4 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EMR67205.1 - 0.037 13.5 0.1 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aldo_ket_red PF00248.16 EMR67206.1 - 3.5e-47 160.5 0.0 4.1e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Macro PF01661.16 EMR67208.1 - 7.6e-39 132.2 0.1 1.8e-38 131.1 0.0 1.6 2 0 0 2 2 2 1 Macro domain Neuromodulin PF06614.6 EMR67208.1 - 0.0032 17.4 7.6 0.0032 17.4 5.3 1.5 2 0 0 2 2 2 1 Neuromodulin Ank_2 PF12796.2 EMR67209.1 - 9.8e-29 99.5 0.1 3e-08 33.8 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMR67209.1 - 2.3e-23 82.1 3.2 2.6e-05 24.6 0.0 6.3 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 EMR67209.1 - 2.1e-19 68.2 6.7 0.00014 21.5 0.0 8.7 9 1 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.1 EMR67209.1 - 1.4e-14 53.7 0.5 0.0063 16.7 0.0 6.2 3 3 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR67209.1 - 9.7e-14 50.1 4.8 0.14 12.4 0.0 8.1 7 1 0 7 7 7 3 Ankyrin repeat ZZ PF00569.12 EMR67209.1 - 0.0008 18.8 9.0 0.0014 18.0 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.11 EMR67209.1 - 9 6.5 10.2 15 5.7 7.0 1.4 1 0 0 1 1 1 0 C1 domain Zip PF02535.17 EMR67211.1 - 1e-27 97.0 9.3 7.8e-21 74.4 2.7 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter Mito_carr PF00153.22 EMR67213.1 - 1.9e-28 98.0 0.2 3.9e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein SCA7 PF08313.7 EMR67214.1 - 1e-34 117.9 0.6 3.1e-34 116.4 0.5 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain MFS_1 PF07690.11 EMR67216.1 - 2.9e-17 62.4 11.5 2.9e-17 62.4 8.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Iso_dh PF00180.15 EMR67218.1 - 1.1e-86 290.9 0.0 1.2e-86 290.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Abhydrolase_6 PF12697.2 EMR67219.1 - 6.1e-37 127.6 1.8 7.2e-37 127.4 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR67219.1 - 8.3e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR67219.1 - 3.4e-13 49.5 0.0 5.7e-13 48.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EMR67219.1 - 1.3e-06 28.7 0.0 3.6e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 EMR67219.1 - 1.7e-06 27.7 0.0 4.7e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EMR67219.1 - 0.0015 17.8 0.0 0.028 13.7 0.0 2.6 2 1 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 EMR67219.1 - 0.0031 16.0 0.0 0.0092 14.5 0.0 1.8 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.6 EMR67219.1 - 0.004 15.9 0.0 0.018 13.8 0.0 1.8 1 1 0 1 1 1 1 Chlorophyllase Ndr PF03096.9 EMR67219.1 - 0.023 13.1 0.0 0.19 10.1 0.0 2.1 2 0 0 2 2 2 0 Ndr family Chlorophyllase2 PF12740.2 EMR67219.1 - 0.078 11.8 0.0 0.97 8.2 0.0 2.1 1 1 0 1 1 1 0 Chlorophyllase enzyme Pkinase PF00069.20 EMR67220.1 - 3.7e-68 229.4 0.0 6.8e-68 228.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR67220.1 - 2.6e-36 125.0 0.0 6.4e-36 123.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR67220.1 - 4e-09 35.8 0.0 8.7e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMR67220.1 - 0.0047 16.6 0.1 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EMR67220.1 - 0.035 12.9 0.0 0.064 12.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2855 PF11017.3 EMR67221.1 - 1.6e-42 145.7 0.1 1e-41 143.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2855) zf-C2H2_jaz PF12171.3 EMR67222.1 - 1.3e-11 44.2 33.6 0.00058 19.9 0.6 7.1 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMR67222.1 - 1.5e-11 44.2 28.8 0.042 13.9 1.3 6.6 2 2 5 7 7 7 5 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EMR67222.1 - 2.1e-11 43.4 40.3 0.082 13.2 0.3 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR67222.1 - 5.4e-11 42.0 25.1 0.2 12.0 0.6 7.5 6 1 1 7 7 7 5 C2H2-type zinc finger zf-met PF12874.2 EMR67222.1 - 7.6e-10 38.6 31.6 0.0031 17.6 0.3 7.0 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EMR67222.1 - 2.6e-08 33.7 26.4 0.15 12.4 0.3 7.5 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_6 PF13912.1 EMR67222.1 - 0.00011 21.9 22.9 0.21 11.5 0.5 6.8 7 0 0 7 7 7 3 C2H2-type zinc finger zf-Di19 PF05605.7 EMR67222.1 - 0.12 12.4 0.3 0.12 12.4 0.2 4.8 3 2 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 EMR67222.1 - 0.16 11.6 20.1 2.4 7.9 0.4 5.9 6 0 0 6 6 6 0 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.9 EMR67222.1 - 0.43 10.0 2.1 27 4.3 0.0 3.7 4 0 0 4 4 4 0 Rad50 zinc hook motif HNH_5 PF14279.1 EMR67222.1 - 1.8 8.5 11.0 30 4.6 0.4 4.1 3 1 0 3 3 3 0 HNH endonuclease Churchill PF06573.6 EMR67222.1 - 3.9 7.5 11.1 1.6 8.7 1.2 2.4 1 1 1 2 2 2 0 Churchill protein AKAP95 PF04988.7 EMR67222.1 - 5 6.8 14.2 0.54 10.0 0.4 3.6 2 1 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) Elf1 PF05129.8 EMR67222.1 - 5.8 6.6 14.4 1.1 9.0 0.3 3.9 2 1 2 4 4 4 0 Transcription elongation factor Elf1 like NmrA PF05368.8 EMR67223.1 - 0.00073 18.8 0.0 0.0016 17.7 0.0 1.6 1 1 1 2 2 2 1 NmrA-like family adh_short PF00106.20 EMR67223.1 - 0.0019 18.1 0.0 0.0031 17.4 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR67223.1 - 0.0027 17.5 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.12 EMR67223.1 - 0.019 13.8 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 EMR67223.1 - 0.066 13.2 0.0 0.097 12.6 0.0 1.3 1 1 0 1 1 1 0 NADH(P)-binding Fungal_trans PF04082.13 EMR67224.1 - 1.9e-07 30.2 0.0 2.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1772 PF08592.6 EMR67225.1 - 2.2e-24 85.7 6.9 2.6e-24 85.5 4.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DoxX_2 PF13564.1 EMR67225.1 - 0.086 12.8 3.5 3.5 7.6 0.4 2.3 2 0 0 2 2 2 0 DoxX-like family Lactamase_B PF00753.22 EMR67226.1 - 1.8e-24 86.5 3.5 2.4e-24 86.0 2.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMR67226.1 - 1.7e-05 24.4 0.9 3.4e-05 23.4 0.6 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain PG_binding_3 PF09374.5 EMR67227.1 - 0.00036 20.4 9.3 8.9 6.3 0.3 4.9 1 1 4 5 5 5 5 Predicted Peptidoglycan domain GlcNAc PF11397.3 EMR67227.1 - 0.37 9.8 3.5 51 2.8 0.0 4.0 1 1 4 5 5 5 0 Glycosyltransferase (GlcNAc) XLF PF09302.6 EMR67228.1 - 6.9e-30 104.0 0.1 1e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 XLF (XRCC4-like factor) HTH_24 PF13412.1 EMR67229.1 - 0.032 13.6 0.0 0.079 12.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_31 PF13560.1 EMR67229.1 - 0.053 13.7 0.0 3.3 7.9 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EMR67229.1 - 0.079 12.1 0.0 0.29 10.3 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_3 PF01381.17 EMR67229.1 - 0.092 12.6 0.0 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix adh_short PF00106.20 EMR67230.1 - 4.1e-18 65.8 0.1 1.7e-17 63.8 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.11 EMR67230.1 - 2.5e-13 49.4 44.5 3.2e-12 45.8 30.6 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily KR PF08659.5 EMR67230.1 - 3.1e-09 36.7 0.0 4.9e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 KR domain TRI12 PF06609.8 EMR67230.1 - 6.9e-09 34.4 16.2 1.1e-08 33.7 11.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Saccharop_dh PF03435.13 EMR67230.1 - 0.012 14.6 0.1 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EMR67230.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GST_C PF00043.20 EMR67231.1 - 5e-12 45.6 0.0 1.2e-11 44.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMR67231.1 - 2.3e-10 40.5 0.0 4.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMR67231.1 - 8.1e-08 32.3 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR67231.1 - 5.7e-07 29.3 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR67231.1 - 1.6e-06 28.4 0.0 2.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMR67231.1 - 0.0002 21.2 0.0 0.00042 20.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain adh_short PF00106.20 EMR67232.1 - 1.9e-19 70.1 1.2 3.7e-19 69.2 0.8 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR67232.1 - 4.9e-12 45.8 0.4 1.1e-11 44.7 0.4 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMR67233.1 - 1.6e-23 83.7 0.4 3.9e-22 79.2 0.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR67233.1 - 7.2e-21 74.8 0.4 2.6e-20 72.9 0.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR67233.1 - 6.7e-07 29.1 0.1 1.6e-06 27.9 0.1 1.7 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMR67233.1 - 0.048 12.7 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ketoacyl-synt PF00109.21 EMR67234.1 - 8.8e-74 248.1 0.1 5.9e-72 242.1 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMR67234.1 - 5.8e-46 157.2 1.1 1.2e-45 156.2 0.4 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EMR67234.1 - 3.6e-31 107.4 4.4 5.4e-31 106.9 1.8 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EMR67234.1 - 6e-12 45.6 0.3 1.5e-11 44.4 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EMR67234.1 - 6.9e-05 21.9 0.1 0.00034 19.6 0.1 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 EMR67234.1 - 0.005 16.5 0.1 0.014 15.1 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family GMC_oxred_C PF05199.8 EMR67235.1 - 1.7e-38 132.1 0.1 2.6e-38 131.5 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR67235.1 - 8.7e-36 123.5 0.0 1.9e-35 122.4 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase NAD_binding_10 PF13460.1 EMR67236.1 - 1.4e-12 47.9 0.0 1.9e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR67236.1 - 1.3e-07 31.1 0.0 1.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EMR67236.1 - 0.0018 17.7 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR67236.1 - 0.006 15.3 0.0 0.0079 14.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMR67236.1 - 0.0073 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EMR67236.1 - 0.067 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.7 EMR67236.1 - 0.12 11.3 0.0 0.3 9.9 0.0 1.7 1 1 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.19 EMR67236.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.17 EMR67238.1 - 2.9e-51 174.4 0.0 3.4e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2621 PF11084.3 EMR67238.1 - 0.089 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) HTH_34 PF13601.1 EMR67238.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain GMC_oxred_C PF05199.8 EMR67239.1 - 3.3e-31 108.5 0.0 5.4e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR67239.1 - 2.2e-19 69.7 0.0 2.9e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase DUF4243 PF14027.1 EMR67240.1 - 1.4e-83 281.0 0.2 1.9e-83 280.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Scytalone_dh PF02982.9 EMR67241.1 - 1.9e-69 232.2 2.0 2.2e-69 232.1 1.4 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EMR67241.1 - 1.2e-08 34.8 0.7 1.5e-08 34.6 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain Methyltransf_4 PF02390.12 EMR67241.1 - 0.0044 16.0 0.0 2.2 7.2 0.0 2.1 1 1 1 2 2 2 2 Putative methyltransferase SnoaL_3 PF13474.1 EMR67241.1 - 0.0049 16.9 2.7 0.31 11.0 1.9 2.2 1 1 0 1 1 1 1 SnoaL-like domain RNA_pol_3_Rpc31 PF11705.3 EMR67242.1 - 3.6e-21 76.1 47.9 6.4e-15 55.7 8.5 3.2 1 1 1 2 2 2 2 DNA-directed RNA polymerase III subunit Rpc31 Gly-rich_Ago1 PF12764.2 EMR67242.1 - 6.4 7.4 10.9 0.31 11.6 2.7 2.3 2 0 0 2 2 2 0 Glycine-rich region of argonaut AAA PF00004.24 EMR67243.1 - 3.8e-13 49.7 0.0 1.5e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EMR67243.1 - 0.0035 17.0 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EMR67243.1 - 0.035 13.8 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMR67243.1 - 0.039 14.7 1.6 0.22 12.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain SyrA PF11089.3 EMR67243.1 - 0.33 10.7 0.0 0.58 10.0 0.0 1.3 1 0 0 1 1 1 0 Exopolysaccharide production repressor AAA_22 PF13401.1 EMR67243.1 - 0.47 10.5 2.6 3.7 7.6 0.1 2.9 2 1 1 3 3 3 0 AAA domain SlyX PF04102.7 EMR67243.1 - 6.8 7.1 9.2 1.9 8.9 3.3 2.3 2 0 0 2 2 2 0 SlyX Proteasom_PSMB PF10508.4 EMR67244.1 - 0.0067 14.7 0.8 0.026 12.8 0.0 1.9 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit Fungal_trans PF04082.13 EMR67245.1 - 9.3e-16 57.4 0.1 1.5e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain M_domain PF12938.2 EMR67246.1 - 0.0069 16.2 2.7 0.0098 15.7 1.8 1.2 1 0 0 1 1 1 1 M domain of GW182 CbiG_N PF11760.3 EMR67246.1 - 0.036 13.7 0.9 0.036 13.7 0.6 1.9 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal MFS_1 PF07690.11 EMR67247.1 - 8.1e-39 133.3 26.7 2.2e-34 118.7 14.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PKD_channel PF08016.7 EMR67248.1 - 4e-05 22.2 21.6 0.00023 19.7 15.0 2.0 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 EMR67248.1 - 0.00013 21.2 26.1 0.049 12.8 18.1 2.4 1 1 0 1 1 1 1 Ion transport protein HALZ PF02183.13 EMR67248.1 - 0.12 12.1 1.0 0.28 10.9 0.7 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Sec7 PF01369.15 EMR67249.1 - 3e-64 216.1 0.1 1.3e-63 214.0 0.1 2.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EMR67249.1 - 1.8e-36 125.1 7.6 1.4e-20 73.4 0.1 3.6 2 1 1 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EMR67249.1 - 6.8e-30 102.4 0.0 6.8e-30 102.4 0.0 4.7 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) 2-oxoacid_dh PF00198.18 EMR67250.1 - 2.2e-77 259.4 0.3 2.9e-77 259.0 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EMR67250.1 - 1.6e-18 66.1 2.2 4.2e-18 64.7 1.5 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EMR67250.1 - 2.2e-11 43.1 0.5 5.3e-11 41.9 0.3 1.7 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.3 EMR67250.1 - 0.022 15.0 0.1 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) Fungal_trans_2 PF11951.3 EMR67251.1 - 2.6e-09 36.1 1.8 2e-08 33.2 1.2 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain MOSC_N PF03476.11 EMR67252.1 - 3.7e-14 52.4 0.0 8e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EMR67252.1 - 1.2e-09 37.7 0.0 2.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 MOSC domain NOT2_3_5 PF04153.13 EMR67253.1 - 5.5e-31 107.2 3.2 8.3e-31 106.6 2.2 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Mob1_phocein PF03637.12 EMR67254.1 - 3.5e-25 88.6 0.1 6e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 Mob1/phocein family AAA_2 PF07724.9 EMR67255.1 - 1.8e-33 115.9 0.1 2e-29 102.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EMR67255.1 - 8.6e-11 42.1 0.0 2.1e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EMR67255.1 - 3.8e-08 33.1 0.1 9.4e-08 31.8 0.1 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EMR67255.1 - 2.7e-05 23.9 0.0 5.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EMR67255.1 - 0.0067 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMR67255.1 - 0.0076 17.0 0.3 0.023 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Pex14_N PF04695.8 EMR67255.1 - 0.008 16.2 2.9 0.21 11.6 0.0 2.3 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_16 PF13191.1 EMR67255.1 - 0.024 14.6 0.2 1 9.2 0.0 2.3 2 1 0 3 3 3 0 AAA ATPase domain L27_1 PF09058.5 EMR67255.1 - 0.055 13.3 0.2 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 L27_1 AAA_22 PF13401.1 EMR67255.1 - 0.059 13.5 0.2 0.59 10.2 0.1 2.5 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 EMR67255.1 - 0.076 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase MCM PF00493.18 EMR67255.1 - 0.14 10.9 2.2 0.29 9.8 0.0 2.2 2 1 0 2 2 2 0 MCM2/3/5 family ORC5_C PF14630.1 EMR67256.1 - 2.4e-59 201.0 0.0 1.2e-58 198.6 0.0 1.9 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EMR67256.1 - 4.8e-12 46.2 0.3 1.6e-11 44.5 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMR67256.1 - 0.002 18.2 0.0 0.0062 16.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EMR67256.1 - 0.029 14.0 0.0 0.16 11.6 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Alpha-amylase_C PF02806.13 EMR67258.1 - 1.8e-25 88.9 0.1 4.1e-25 87.7 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EMR67258.1 - 1.1e-19 71.0 0.1 1.3e-14 54.3 0.1 2.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EMR67258.1 - 3.2e-18 65.5 0.0 1.1e-17 63.8 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) eIF-3c_N PF05470.7 EMR67259.1 - 4.7e-176 586.3 20.2 1.3e-146 489.2 1.2 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EMR67259.1 - 5.1e-14 52.4 0.1 6.2e-13 48.9 0.0 2.7 2 0 0 2 2 2 1 PCI domain CDC45 PF02724.9 EMR67259.1 - 3.2 5.6 21.0 5.2 4.9 14.6 1.4 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EMR67259.1 - 5.2 5.4 30.9 8.8 4.6 21.4 1.4 1 0 0 1 1 1 0 Daxx Family AAA_12 PF13087.1 EMR67260.1 - 2.9e-26 92.0 0.1 1.6e-25 89.6 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 EMR67260.1 - 1.1e-10 41.5 0.0 2.2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EMR67260.1 - 0.0048 16.4 0.2 0.94 8.9 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EMR67260.1 - 0.12 11.9 0.1 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3829 PF12889.2 EMR67261.1 - 0.016 14.4 1.5 0.02 14.0 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Uds1 PF15456.1 EMR67261.1 - 0.023 14.7 2.3 0.028 14.3 1.6 1.1 1 0 0 1 1 1 0 Up-regulated During Septation Rapamycin_bind PF08771.6 EMR67261.1 - 0.14 12.2 0.6 0.18 11.8 0.4 1.2 1 0 0 1 1 1 0 Rapamycin binding domain DUF4200 PF13863.1 EMR67261.1 - 0.42 10.5 5.5 0.072 13.0 0.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) NmrA PF05368.8 EMR67262.1 - 1.6e-32 112.6 0.0 2.2e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR67262.1 - 4.9e-10 39.7 0.0 8.6e-10 38.9 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR67262.1 - 0.0018 17.7 0.0 0.0035 16.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMR67262.1 - 0.0083 16.0 0.1 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EMR67262.1 - 0.024 13.5 0.1 0.57 9.0 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.14 EMR67262.1 - 0.041 12.5 0.1 0.072 11.7 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3553 PF12073.3 EMR67262.1 - 0.079 12.2 0.3 0.16 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) HET PF06985.6 EMR67263.1 - 7e-21 74.8 4.8 1.9e-17 63.7 0.6 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF2346 PF09803.4 EMR67264.1 - 0.00052 19.8 5.2 0.001 18.8 3.6 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) FAD_binding_4 PF01565.18 EMR67265.1 - 2.7e-24 85.2 0.6 5.4e-24 84.2 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_11 PF00457.12 EMR67265.1 - 0.011 15.1 0.2 0.019 14.3 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 DUF1772 PF08592.6 EMR67266.1 - 1e-13 51.1 0.9 1.3e-13 50.8 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Hemerythrin PF01814.18 EMR67267.1 - 6.2e-15 55.5 0.1 8.4e-15 55.1 0.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HEAT_2 PF13646.1 EMR67269.1 - 8.9e-14 51.5 6.1 0.0068 16.6 0.0 7.5 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.17 EMR67269.1 - 1.6e-09 37.0 19.5 0.12 12.5 0.0 10.6 11 0 0 11 11 11 3 HEAT repeat Vac14_Fab1_bd PF12755.2 EMR67269.1 - 8e-08 32.5 0.0 0.055 13.8 0.0 6.0 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EMR67269.1 - 2.5e-06 27.0 6.0 0.17 11.2 0.0 5.5 4 1 1 5 5 5 2 CLASP N terminal DUF3554 PF12074.3 EMR67269.1 - 8e-05 22.2 4.7 2.1 7.7 0.1 4.2 4 0 0 4 4 4 3 Domain of unknown function (DUF3554) V-ATPase_H_C PF11698.3 EMR67269.1 - 0.014 15.3 0.0 0.12 12.2 0.0 2.7 3 0 0 3 3 3 0 V-ATPase subunit H Adaptin_N PF01602.15 EMR67269.1 - 0.015 13.6 3.9 5.1 5.2 0.0 4.7 5 0 0 5 5 5 0 Adaptin N terminal region FAD_binding_3 PF01494.14 EMR67270.1 - 7e-10 38.4 0.1 0.00016 20.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 EMR67270.1 - 0.093 11.1 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Transcrip_reg PF01709.15 EMR67272.1 - 9.7e-44 149.2 0.0 1.2e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator Motile_Sperm PF00635.21 EMR67273.1 - 6.9e-19 67.5 0.1 1.2e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF756 PF05506.7 EMR67273.1 - 0.14 12.7 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF756) FA_desaturase PF00487.19 EMR67274.1 - 7.2e-34 117.3 14.2 1.1e-33 116.8 9.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EMR67274.1 - 2.3e-19 68.3 1.3 3e-19 67.9 0.2 1.7 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) Na_Ca_ex PF01699.19 EMR67275.1 - 1.9e-09 37.2 0.7 2.3e-09 37.0 0.5 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein MARVEL PF01284.18 EMR67275.1 - 0.017 14.9 0.3 0.018 14.8 0.2 1.1 1 0 0 1 1 1 0 Membrane-associating domain HemY_N PF07219.8 EMR67275.1 - 0.41 10.2 2.9 0.65 9.5 2.0 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Cnd2 PF05786.9 EMR67276.1 - 1.8e-194 648.3 0.1 2e-130 436.5 0.0 2.0 1 1 1 2 2 2 2 Condensin complex subunit 2 Gag_p15 PF08723.5 EMR67276.1 - 0.12 12.3 0.2 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 Gag protein p15 SAM_1 PF00536.25 EMR67277.1 - 3.4e-09 36.7 0.4 6.3e-09 35.8 0.0 1.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box PF00505.14 EMR67277.1 - 1.9e-07 31.2 10.3 4.7e-07 29.9 1.7 2.6 2 1 1 3 3 3 2 HMG (high mobility group) box SAM_2 PF07647.12 EMR67277.1 - 4.6e-07 29.5 0.0 8.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.5 EMR67277.1 - 4.2e-06 27.0 1.8 4.2e-06 27.0 1.3 2.6 2 1 1 3 3 3 1 HMG-box domain Gly-zipper_OmpA PF13436.1 EMR67277.1 - 0.073 12.7 2.1 0.16 11.6 1.4 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain HMG_box_5 PF14887.1 EMR67277.1 - 0.12 12.1 4.0 0.13 12.0 0.7 2.0 1 1 1 2 2 2 0 HMG (high mobility group) box 5 DUF3811 PF11656.3 EMR67277.1 - 0.4 10.7 3.8 0.77 9.8 2.6 1.4 1 0 0 1 1 1 0 YjbD family (DUF3811) PMM PF03332.8 EMR67278.1 - 1.7e-101 338.3 0.0 2e-101 338.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EMR67278.1 - 0.00014 21.4 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Glyco_hydro_92 PF07971.7 EMR67280.1 - 8.4e-26 90.6 0.0 9.3e-26 90.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 RhgB_N PF09284.5 EMR67284.1 - 3.5e-67 226.3 2.9 5.9e-67 225.6 2.0 1.4 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EMR67284.1 - 7.7e-47 159.0 2.7 1.3e-46 158.2 0.1 2.4 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EMR67284.1 - 1.6e-15 56.9 1.3 1.6e-15 56.9 0.9 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EMR67284.1 - 0.0059 16.6 1.4 0.015 15.3 0.2 2.4 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain RicinB_lectin_2 PF14200.1 EMR67284.1 - 0.045 14.1 2.6 0.12 12.7 0.0 3.0 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like F-box-like PF12937.2 EMR67285.1 - 1.1e-08 34.6 0.0 5.3e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMR67285.1 - 1.4e-07 30.9 0.8 3.6e-07 29.6 0.0 2.1 2 1 0 2 2 2 1 F-box domain PRANC PF09372.5 EMR67285.1 - 0.14 12.1 0.2 0.36 10.8 0.1 1.7 1 0 0 1 1 1 0 PRANC domain Vac7 PF12751.2 EMR67286.1 - 6.4e-73 245.8 13.9 5.1e-57 193.4 5.8 2.7 2 1 1 3 3 3 2 Vacuolar segregation subunit 7 DUF2110 PF09883.4 EMR67288.1 - 0.0062 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2110) BAF1_ABF1 PF04684.8 EMR67288.1 - 0.11 11.3 7.1 0.22 10.3 4.9 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Amidohydro_2 PF04909.9 EMR67289.1 - 2.2e-07 30.7 0.0 3.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EMR67289.1 - 0.00028 21.0 0.0 0.00032 20.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Ribosomal_L7Ae PF01248.21 EMR67290.1 - 2.5e-25 87.8 0.0 2.8e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.13 EMR67291.1 - 4.1e-31 107.4 0.1 5.2e-31 107.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e SKG6 PF08693.5 EMR67292.1 - 5.3e-05 22.4 0.5 0.0001 21.5 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.8 EMR67292.1 - 0.021 13.4 0.3 0.028 13.0 0.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Herpes_gE PF02480.11 EMR67292.1 - 0.075 11.2 0.0 0.083 11.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E AAA_2 PF07724.9 EMR67293.1 - 8.3e-06 25.8 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EMR67293.1 - 0.018 14.9 0.0 0.056 13.3 0.0 1.9 1 1 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EMR67293.1 - 0.032 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EMR67293.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Spt20 PF12090.3 EMR67294.1 - 0.23 10.7 8.0 0.91 8.8 1.9 2.4 2 0 0 2 2 2 0 Spt20 family Reo_sigmaC PF04582.7 EMR67296.1 - 0.002 17.4 3.1 0.0034 16.6 2.1 1.4 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Z1 PF10593.4 EMR67296.1 - 0.046 12.9 5.8 0.096 11.8 4.0 1.6 1 0 0 1 1 1 0 Z1 domain LMBR1 PF04791.11 EMR67296.1 - 0.39 9.2 7.9 0.57 8.7 5.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Tweety PF04906.8 EMR67296.1 - 0.54 8.6 3.2 0.81 8.0 2.2 1.2 1 0 0 1 1 1 0 Tweety HeLo PF14479.1 EMR67296.1 - 0.58 9.8 10.8 2.2 7.9 7.5 2.0 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF87 PF01935.12 EMR67296.1 - 0.86 9.3 8.6 11 5.7 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 V_ATPase_I PF01496.14 EMR67296.1 - 1.7 6.3 16.8 1.3 6.8 8.6 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.3 EMR67296.1 - 2.7 7.1 20.2 4.2 6.5 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) IncA PF04156.9 EMR67296.1 - 2.8 7.5 38.7 0.13 11.8 15.0 3.1 3 0 0 3 3 3 0 IncA protein Laminin_II PF06009.7 EMR67296.1 - 6.1 6.5 16.0 26 4.5 8.5 2.6 2 1 0 2 2 2 0 Laminin Domain II HAUS6_N PF14661.1 EMR67296.1 - 6.4 6.0 15.4 20 4.4 10.6 1.9 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Fib_alpha PF08702.5 EMR67296.1 - 6.8 6.8 20.3 3.9 7.5 5.4 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CwfJ_C_1 PF04677.10 EMR67297.1 - 3.5e-29 100.9 0.0 6.2e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EMR67297.1 - 2.1e-24 85.8 0.0 7e-24 84.1 0.0 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 BTB PF00651.26 EMR67299.1 - 4.6e-08 33.0 0.0 1.2e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Peptidase_S24 PF00717.18 EMR67300.1 - 4e-07 29.5 0.0 6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like TFIIB PF00382.14 EMR67301.1 - 1.3e-27 95.4 0.0 1.4e-18 66.4 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EMR67301.1 - 2.1e-22 79.1 0.4 2.1e-22 79.1 0.3 3.7 4 0 0 4 4 4 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 EMR67301.1 - 0.0023 17.5 0.2 0.43 10.1 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF3606 PF12244.3 EMR67302.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Arginosuc_synth PF00764.14 EMR67303.1 - 2.5e-131 438.2 0.0 3.1e-131 437.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase SRR1 PF07985.7 EMR67305.1 - 0.008 16.0 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 SRR1 Pyridox_oxidase PF01243.15 EMR67307.1 - 2.1e-05 24.4 0.0 7.9e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ThiC-associated PF13667.1 EMR67307.1 - 0.023 14.2 0.5 0.48 10.0 0.1 2.3 2 0 0 2 2 2 0 ThiC-associated domain ketoacyl-synt PF00109.21 EMR67308.1 - 3.2e-83 279.0 2.0 6.7e-83 278.0 0.0 2.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMR67308.1 - 4.1e-59 200.5 0.6 2.2e-49 168.4 0.3 3.0 2 1 1 3 3 3 2 Acyl transferase domain KR PF08659.5 EMR67308.1 - 3.9e-58 196.1 0.0 7.9e-58 195.0 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR67308.1 - 1.1e-50 171.8 0.0 2.5e-50 170.6 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMR67308.1 - 2.7e-39 133.6 2.7 7.3e-39 132.2 1.2 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EMR67308.1 - 1e-14 54.3 0.0 2.4e-14 53.1 0.0 1.6 1 1 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EMR67308.1 - 2.1e-08 34.3 0.0 5.6e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 EMR67308.1 - 3.6e-05 23.8 0.0 0.00013 22.0 0.0 2.0 1 0 0 1 1 1 1 NADH(P)-binding Thiolase_N PF00108.18 EMR67308.1 - 3.7e-05 22.8 0.1 8.9e-05 21.5 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 EMR67308.1 - 0.2 10.5 0.0 0.35 9.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EMR67309.1 - 1.4e-09 37.7 0.7 0.00018 21.0 0.0 2.3 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR67309.1 - 0.00033 19.4 0.0 0.077 11.6 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMR67309.1 - 0.00039 20.4 0.0 0.03 14.3 0.0 2.4 1 1 1 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EMR67309.1 - 0.011 15.0 0.0 0.1 11.8 0.0 2.2 1 1 1 2 2 2 0 NmrA-like family NAD_binding_4 PF07993.7 EMR67309.1 - 0.023 13.6 0.1 0.41 9.5 0.0 2.1 1 1 1 2 2 2 0 Male sterility protein adh_short PF00106.20 EMR67309.1 - 0.032 14.1 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 short chain dehydrogenase Cupin_2 PF07883.6 EMR67310.1 - 0.0042 16.5 0.4 0.015 14.7 0.1 1.9 2 0 0 2 2 2 1 Cupin domain Arginase PF00491.16 EMR67311.1 - 6.2e-86 288.1 0.0 7.8e-86 287.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family DUF3414 PF11894.3 EMR67312.1 - 0 1188.1 2.6 1.7e-211 704.8 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3414) Voltage_CLC PF00654.15 EMR67313.1 - 3e-33 115.3 12.7 4e-33 114.9 8.8 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 EMR67313.1 - 3.3e-07 29.9 0.0 0.036 13.8 0.0 2.7 2 0 0 2 2 2 2 CBS domain LacI PF00356.16 EMR67313.1 - 0.32 10.6 1.2 0.7 9.5 0.9 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF1301 PF06979.7 EMR67313.1 - 0.39 10.8 4.6 6.6 6.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1301) His_Phos_2 PF00328.17 EMR67314.1 - 2.3e-22 79.8 0.0 5.9e-21 75.1 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RTA1 PF04479.8 EMR67315.1 - 1.9e-20 73.3 0.1 2.7e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4045 PF13254.1 EMR67316.1 - 5.4e-35 121.4 6.9 5.4e-35 121.4 4.8 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EMR67316.1 - 3.8e-09 36.0 0.0 0.00018 21.1 0.0 3.7 3 1 0 3 3 3 2 Gelsolin repeat RRM_6 PF14259.1 EMR67317.1 - 1.2e-39 134.1 0.2 5.7e-11 42.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR67317.1 - 3.2e-34 116.3 0.3 8.9e-11 41.2 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR67317.1 - 2.5e-19 68.8 2.5 4.8e-05 23.1 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EMR67317.1 - 6.5e-12 44.8 2.6 6.5e-12 44.8 1.8 3.7 4 0 0 4 4 4 1 Putative RRM domain RRM_3 PF08777.6 EMR67317.1 - 1e-05 25.3 0.5 0.016 15.0 0.1 2.6 2 0 0 2 2 2 2 RNA binding motif RNA_bind PF08675.6 EMR67317.1 - 0.0077 16.1 0.2 0.087 12.8 0.0 2.6 3 1 0 3 3 3 1 RNA binding domain Nup35_RRM_2 PF14605.1 EMR67317.1 - 0.044 13.5 0.1 21 4.9 0.0 3.2 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.1 EMR67317.1 - 0.055 12.9 0.0 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Ferric_reduct PF01794.14 EMR67318.1 - 1.4e-19 70.3 5.3 1.4e-19 70.3 3.7 1.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EMR67318.1 - 5.6e-17 62.0 0.0 7.5e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMR67318.1 - 1.7e-16 60.0 0.0 3e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EMR67318.1 - 0.15 12.6 0.0 0.99 9.9 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Arf PF00025.16 EMR67319.1 - 2.6e-67 225.4 0.5 2.9e-67 225.2 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EMR67319.1 - 2.2e-12 46.4 1.1 3.3e-07 29.3 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EMR67319.1 - 3.5e-12 46.0 0.0 4.1e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EMR67319.1 - 7e-10 38.4 0.0 8.1e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMR67319.1 - 1.6e-09 38.2 0.0 2.2e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMR67319.1 - 1.5e-08 34.5 0.0 2.1e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMR67319.1 - 2e-07 30.4 0.0 2.4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EMR67319.1 - 6.4e-05 22.4 0.0 0.0025 17.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EMR67319.1 - 0.0054 17.5 0.1 0.0072 17.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EMR67319.1 - 0.013 15.1 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 EMR67319.1 - 0.088 12.3 0.1 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EMR67319.1 - 0.11 11.8 0.3 0.27 10.5 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B ATHILA PF03078.10 EMR67319.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family AAA_33 PF13671.1 EMR67319.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.13 EMR67319.1 - 0.15 11.1 0.1 0.38 9.7 0.0 1.6 1 1 0 2 2 2 0 6-phosphofructo-2-kinase PI3_PI4_kinase PF00454.22 EMR67320.1 - 9.2e-47 159.4 0.0 1.5e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EMR67320.1 - 4.5e-08 32.3 0.1 8.7e-08 31.4 0.0 1.5 1 0 0 1 1 1 1 FATC domain FAT PF02259.18 EMR67320.1 - 0.0013 17.7 2.2 0.0013 17.7 1.5 1.9 2 0 0 2 2 2 1 FAT domain FAM74 PF15026.1 EMR67320.1 - 0.021 14.4 0.5 0.054 13.1 0.3 1.7 1 0 0 1 1 1 0 FAM74 protein DUF2381 PF09544.5 EMR67320.1 - 0.09 11.8 2.5 0.13 11.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2381) PPR_2 PF13041.1 EMR67321.1 - 5.6e-23 80.6 0.0 1.1e-07 31.6 0.0 7.1 6 1 1 7 7 7 4 PPR repeat family PPR_3 PF13812.1 EMR67321.1 - 1.3e-12 46.9 6.6 0.81 10.1 0.0 10.4 11 0 0 11 11 11 3 Pentatricopeptide repeat domain PPR PF01535.15 EMR67321.1 - 3.6e-10 39.1 0.0 0.22 11.5 0.0 6.8 8 0 0 8 8 8 3 PPR repeat PPR_1 PF12854.2 EMR67321.1 - 1.7e-07 30.6 0.0 0.21 11.1 0.0 5.4 6 0 0 6 6 6 2 PPR repeat TPR_14 PF13428.1 EMR67321.1 - 0.0059 17.1 0.5 13 6.7 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR67321.1 - 0.049 13.9 0.9 1.2 9.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TCTP PF00838.12 EMR67322.1 - 1.3e-56 191.1 0.1 1.5e-56 190.9 0.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DndB PF14072.1 EMR67322.1 - 0.077 12.1 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 DNA-sulfur modification-associated AA_permease PF00324.16 EMR67323.1 - 3.2e-126 421.4 40.3 4e-126 421.1 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR67323.1 - 1.3e-37 129.3 45.5 1.6e-37 129.0 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease ATP-synt_D PF01813.12 EMR67324.1 - 0.024 14.1 2.3 0.031 13.8 0.1 2.1 2 0 0 2 2 2 0 ATP synthase subunit D U1snRNP70_N PF12220.3 EMR67324.1 - 4 7.8 8.7 0.27 11.5 0.2 2.4 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal YqzE PF14038.1 EMR67324.1 - 4.4 7.1 7.6 0.41 10.4 0.1 2.3 2 0 0 2 2 2 0 YqzE-like protein FA_hydroxylase PF04116.8 EMR67325.1 - 4.3e-10 39.9 10.1 8.6e-10 39.0 5.3 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF454 PF04304.8 EMR67326.1 - 1.3 9.1 7.3 8.7 6.4 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF454) Mis12 PF05859.7 EMR67327.1 - 3.3e-38 130.7 0.0 1.6e-37 128.4 0.0 2.0 2 0 0 2 2 2 1 Mis12 protein Nucleo_P87 PF07267.6 EMR67327.1 - 0.021 13.5 2.9 0.029 13.0 2.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1676 PF07898.8 EMR67327.1 - 0.072 13.3 0.8 0.27 11.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) PBP1_TM PF14812.1 EMR67327.1 - 0.19 12.0 14.6 0.44 10.8 10.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glypican PF01153.14 EMR67327.1 - 0.37 9.3 2.0 0.41 9.1 0.4 1.7 2 0 0 2 2 2 0 Glypican Hepatitis_core PF00906.15 EMR67327.1 - 6.8 6.2 7.6 13 5.4 5.3 1.4 1 0 0 1 1 1 0 Hepatitis core antigen PCI PF01399.22 EMR67328.1 - 7.4e-19 68.0 0.4 2.7e-18 66.1 0.0 2.2 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EMR67328.1 - 3.5e-06 26.8 0.1 1e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 EMR67328.1 - 0.00082 18.9 0.2 0.073 12.8 0.0 3.7 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMR67328.1 - 0.0069 16.3 2.9 0.037 13.9 0.2 3.2 2 1 0 3 3 3 1 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 EMR67328.1 - 0.0071 15.4 0.7 0.075 12.0 0.2 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4423 PF14394.1 EMR67328.1 - 0.014 14.9 0.1 0.62 9.5 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4423) TPR_10 PF13374.1 EMR67328.1 - 0.015 15.2 0.0 2.1 8.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMR67328.1 - 0.015 14.8 0.1 0.47 10.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMR67328.1 - 0.021 14.6 3.2 0.15 12.0 0.0 4.0 6 0 0 6 6 5 0 Tetratricopeptide repeat FeoC PF09012.5 EMR67328.1 - 0.029 14.0 0.0 0.082 12.6 0.0 1.8 1 0 0 1 1 1 0 FeoC like transcriptional regulator TPR_11 PF13414.1 EMR67328.1 - 0.068 12.8 1.2 0.36 10.5 0.0 2.9 3 1 1 4 4 3 0 TPR repeat Ipi1_N PF12333.3 EMR67328.1 - 0.1 12.5 0.2 0.44 10.5 0.1 2.0 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation TPR_8 PF13181.1 EMR67328.1 - 0.62 9.9 4.4 0.62 9.9 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Sigma70_ner PF04546.8 EMR67328.1 - 8.6 5.9 10.2 2.8 7.4 4.9 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region GSDH PF07995.6 EMR67329.1 - 1.3e-116 389.2 0.1 1.6e-116 389.0 0.0 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.6 EMR67329.1 - 0.0015 18.2 1.4 3.3 8.0 0.0 4.0 3 0 0 3 3 3 2 Two component regulator propeller NHL PF01436.16 EMR67329.1 - 0.0068 16.3 0.0 1 9.4 0.0 3.5 3 0 0 3 3 3 1 NHL repeat NUDIX PF00293.23 EMR67330.1 - 7.3e-18 64.5 0.1 1.1e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Med17 PF10156.4 EMR67331.1 - 2.4e-63 214.0 0.0 3.2e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Methyltransf_2 PF00891.13 EMR67332.1 - 9.3e-31 106.8 0.0 4.3e-30 104.6 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase PP2C PF00481.16 EMR67334.1 - 1.7e-36 125.9 0.0 3.5e-36 124.9 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMR67334.1 - 6.7e-06 25.6 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EMR67334.1 - 0.012 15.2 0.1 3.4 7.3 0.0 3.1 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) p450 PF00067.17 EMR67335.1 - 1.3e-64 218.4 0.0 1.6e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EMR67336.1 - 4.1e-29 101.6 5.2 6.3e-29 101.0 3.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR67336.1 - 2.8e-12 46.9 0.8 3.7e-12 46.5 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR67336.1 - 7.5e-09 35.4 1.6 1.1e-08 34.9 1.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR67336.1 - 0.00032 20.2 0.4 0.0006 19.3 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EMR67336.1 - 0.00088 18.9 0.4 0.0015 18.1 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EMR67336.1 - 0.0015 17.3 0.0 0.0024 16.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EMR67336.1 - 0.0037 16.5 0.7 0.007 15.6 0.5 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR67336.1 - 0.022 14.7 3.6 0.03 14.3 1.1 2.2 2 1 0 2 2 2 0 NADH(P)-binding F420_oxidored PF03807.12 EMR67336.1 - 0.022 15.1 1.0 0.042 14.2 0.2 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 EMR67336.1 - 0.036 12.9 0.1 0.062 12.1 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain THF_DHG_CYH_C PF02882.14 EMR67336.1 - 0.039 13.0 0.4 0.069 12.2 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 EMR67336.1 - 0.063 13.1 0.3 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMR67336.1 - 0.26 10.4 1.2 0.64 9.1 0.2 1.9 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F-box PF00646.28 EMR67337.1 - 6.6e-06 25.6 0.1 6.6e-06 25.6 0.0 2.5 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EMR67337.1 - 8.2e-06 25.4 2.2 1.2e-05 24.9 0.1 2.3 2 0 0 2 2 2 1 F-box-like Aminotran_1_2 PF00155.16 EMR67337.1 - 0.036 13.0 0.0 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II Ras PF00071.17 EMR67338.1 - 3.8e-53 179.2 0.0 4.6e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR67338.1 - 3.8e-16 59.6 0.0 5.3e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMR67338.1 - 1.1e-09 37.7 0.0 5.3e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMR67338.1 - 3.5e-05 23.0 0.0 4.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EMR67338.1 - 0.0031 17.4 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EMR67338.1 - 0.0037 16.5 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EMR67338.1 - 0.0059 15.3 0.0 0.0066 15.1 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.22 EMR67338.1 - 0.039 13.3 0.0 0.098 12.0 0.0 1.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ribosomal_60s PF00428.14 EMR67338.1 - 0.063 13.6 0.2 0.063 13.6 0.1 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein ABC_tran PF00005.22 EMR67338.1 - 0.09 13.0 0.0 0.15 12.3 0.0 1.4 1 1 0 1 1 1 0 ABC transporter EMP70 PF02990.11 EMR67339.1 - 0.45 8.9 3.1 0.56 8.6 2.2 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 CWC25 PF12542.3 EMR67340.1 - 1.2e-22 80.1 0.1 1.2e-22 80.1 0.0 4.1 4 2 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EMR67340.1 - 6.7e-14 51.6 2.3 6.7e-14 51.6 1.6 2.9 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR RNase_H PF00075.19 EMR67341.1 - 4.2e-14 53.0 0.0 6.4e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 RNase H PhageP22-tail PF09251.5 EMR67341.1 - 0.026 12.8 0.0 0.031 12.5 0.0 1.1 1 0 0 1 1 1 0 Salmonella phage P22 tail-spike Trypan_PARP PF05887.6 EMR67342.1 - 0.0023 17.7 10.6 0.0023 17.7 7.4 1.5 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) SNF2_N PF00176.18 EMR67344.1 - 1.9e-46 158.2 0.5 2.8e-33 114.9 0.1 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EMR67344.1 - 8.3e-13 48.0 0.0 2e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EMR67344.1 - 2e-08 33.7 2.1 3.4e-08 33.0 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMR67344.1 - 1.4e-07 31.2 4.6 3e-07 30.1 3.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMR67344.1 - 2.2e-07 30.7 4.6 4.6e-07 29.7 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMR67344.1 - 1.1e-06 28.1 5.1 2.9e-06 26.8 3.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR67344.1 - 3.6e-06 26.5 4.4 9.4e-06 25.2 3.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.10 EMR67344.1 - 9.8e-06 25.5 1.4 3e-05 23.9 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.1 EMR67344.1 - 2.6e-05 24.0 5.8 2.6e-05 24.0 4.0 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMR67344.1 - 0.0008 19.0 1.3 0.0019 17.8 0.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Baculo_IE-1 PF05290.6 EMR67344.1 - 0.012 15.3 0.9 0.05 13.3 0.1 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 EMR67344.1 - 0.014 14.9 4.7 0.038 13.5 3.2 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.2 EMR67344.1 - 0.027 14.2 5.5 0.06 13.1 3.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon LOH1CR12 PF10158.4 EMR67344.1 - 0.031 14.0 0.2 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 Tumour suppressor protein zf-MIZ PF02891.15 EMR67344.1 - 0.24 10.9 2.1 0.55 9.7 1.4 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger ketoacyl-synt PF00109.21 EMR67345.1 - 1.9e-75 253.6 0.0 3.5e-75 252.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EMR67345.1 - 7.6e-50 169.0 0.0 6.7e-48 162.7 0.0 2.6 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EMR67345.1 - 1.1e-41 142.5 0.0 5.5e-38 130.4 0.0 2.6 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 EMR67345.1 - 6.3e-39 133.3 0.0 1.1e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.16 EMR67345.1 - 6.4e-38 130.8 0.3 1.2e-37 129.9 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EMR67345.1 - 4.2e-28 97.5 0.0 1.3e-27 96.0 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.16 EMR67345.1 - 1.4e-13 50.8 0.0 1.9e-11 43.8 0.0 2.6 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family PS-DH PF14765.1 EMR67345.1 - 4e-13 49.1 0.1 1.1e-10 41.1 0.1 2.6 1 1 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 EMR67345.1 - 1e-07 32.3 0.0 2.6e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR67345.1 - 2.8e-07 30.3 0.0 8.1e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 EMR67345.1 - 1.9e-05 23.4 0.0 5.4e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.1 EMR67345.1 - 0.00022 20.8 0.0 0.0007 19.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR67345.1 - 0.00022 21.6 0.0 0.00055 20.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR67345.1 - 0.00069 19.8 0.3 0.0064 16.7 0.1 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EMR67345.1 - 0.0047 15.9 0.0 0.0096 14.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 EMR67345.1 - 0.0081 16.7 0.0 0.05 14.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Semialdhyde_dh PF01118.19 EMR67345.1 - 0.12 12.7 0.0 0.39 11.0 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ubie_methyltran PF01209.13 EMR67345.1 - 0.49 9.4 0.0 0.92 8.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Trp_DMAT PF11991.3 EMR67346.1 - 2.4e-80 270.4 0.0 6.6e-80 269.0 0.0 1.7 2 1 0 2 2 2 1 Tryptophan dimethylallyltransferase BPL_LplA_LipB PF03099.14 EMR67347.1 - 1.7e-07 31.2 0.0 3.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF3938 PF13074.1 EMR67348.1 - 0.032 14.0 0.5 0.064 13.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) Clr5 PF14420.1 EMR67349.1 - 1.2e-19 69.8 0.5 2.8e-19 68.7 0.3 1.7 1 0 0 1 1 1 1 Clr5 domain SR-25 PF10500.4 EMR67349.1 - 0.86 9.0 11.4 1.5 8.2 7.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ran-binding PF05508.6 EMR67350.1 - 4.8e-42 143.8 0.0 6.8e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein NMO PF03060.10 EMR67351.1 - 0.0027 16.9 0.0 0.0029 16.8 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase DUF1902 PF08972.6 EMR67351.1 - 0.056 12.9 0.0 0.099 12.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1902) GTP_EFTU PF00009.22 EMR67352.1 - 9.9e-32 109.8 0.1 1.2e-29 103.1 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMR67352.1 - 8.7e-21 73.9 0.5 2e-20 72.7 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMR67352.1 - 4.8e-09 36.2 1.5 2.5e-08 33.9 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RCR PF12273.3 EMR67352.1 - 0.53 10.8 12.8 1.5 9.3 8.9 1.9 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Med15 PF09606.5 EMR67352.1 - 3 5.9 25.9 4.4 5.3 18.0 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal G-alpha PF00503.15 EMR67352.1 - 9 4.8 9.9 46 2.5 6.9 1.9 1 1 0 1 1 1 0 G-protein alpha subunit SNF2_N PF00176.18 EMR67353.1 - 2.9e-75 252.8 0.4 6e-75 251.8 0.3 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMR67353.1 - 3.9e-11 42.6 0.0 8.7e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 EMR67353.1 - 0.0025 17.2 0.0 0.0025 17.2 0.0 2.1 2 0 0 2 2 2 1 DEAD_2 FAD_binding_3 PF01494.14 EMR67355.1 - 3.2e-17 62.6 1.9 4.5e-10 39.1 0.4 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMR67355.1 - 1.4e-05 24.9 0.1 3.8e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR67355.1 - 0.0098 15.7 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR67355.1 - 0.011 14.6 0.0 0.5 9.2 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EMR67355.1 - 0.052 12.6 0.0 0.3 10.0 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EMR67355.1 - 0.062 13.7 0.1 0.37 11.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EMR67358.1 - 1.7e-39 134.7 0.1 1.4e-38 131.8 0.0 2.5 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.8 EMR67358.1 - 5.9e-21 74.7 0.9 1e-20 74.0 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EMR67358.1 - 1.5e-11 44.6 0.4 4.8e-11 42.9 0.2 2.0 3 0 0 3 3 3 1 NADH(P)-binding 2-Hacid_dh PF00389.25 EMR67358.1 - 2.2e-08 33.6 0.0 6.5e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Semialdhyde_dh PF01118.19 EMR67358.1 - 0.00094 19.4 1.3 0.14 12.4 0.1 3.0 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EMR67358.1 - 0.0015 17.2 0.1 0.0028 16.3 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMR67358.1 - 0.028 13.8 0.3 0.12 11.8 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family MukB PF04310.7 EMR67358.1 - 0.072 12.4 0.5 0.16 11.2 0.3 1.5 1 0 0 1 1 1 0 MukB N-terminal DapB_N PF01113.15 EMR67358.1 - 0.14 12.0 2.9 1.2 9.0 0.2 2.8 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus PhrC_PhrF PF11131.3 EMR67359.1 - 1.2 8.7 0.0 1.2 8.7 0.0 2.5 3 0 0 3 3 3 0 Rap-phr extracellular signalling adh_short PF00106.20 EMR67360.1 - 4.7e-23 81.9 0.8 7.9e-23 81.1 0.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR67360.1 - 1e-11 44.8 0.1 1.8e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EMR67360.1 - 0.0075 15.0 0.1 0.15 10.7 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Kinesin PF00225.18 EMR67362.1 - 6.7e-65 218.9 0.1 6.7e-65 218.9 0.1 3.2 3 1 1 4 4 4 1 Kinesin motor domain AAA_22 PF13401.1 EMR67362.1 - 0.2 11.8 0.0 0.2 11.8 0.0 3.8 4 0 0 4 4 4 0 AAA domain p450 PF00067.17 EMR67364.1 - 6.4e-11 41.4 0.0 7.4e-11 41.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_3 PF00933.16 EMR67365.1 - 1.1e-52 178.9 0.0 1.5e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR67365.1 - 2.4e-42 145.0 0.0 4e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR67365.1 - 3.8e-07 29.9 0.0 7.6e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Alpha-L-AF_C PF06964.7 EMR67366.1 - 5.1e-38 130.6 0.0 7.4e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Glyco_hydro_25 PF01183.15 EMR67367.1 - 2.3e-39 135.0 0.1 2.6e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 BTB PF00651.26 EMR67368.1 - 0.01 15.8 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain Podoplanin PF05808.6 EMR67369.1 - 0.027 14.0 0.1 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 Podoplanin Herpes_gE PF02480.11 EMR67369.1 - 0.04 12.1 0.3 0.079 11.2 0.2 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Mito_fiss_reg PF05308.6 EMR67369.1 - 0.18 11.1 12.4 0.1 11.9 6.9 1.8 1 1 0 1 1 1 0 Mitochondrial fission regulator EMG1 PF03587.9 EMR67370.1 - 1.4e-77 259.5 0.0 1.6e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase CorA PF01544.13 EMR67371.1 - 0.0033 16.5 6.1 0.0094 15.0 4.2 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PrgI PF12666.2 EMR67371.1 - 0.0037 17.3 0.4 0.0082 16.2 0.3 1.5 1 0 0 1 1 1 1 PrgI family protein PgaD PF13994.1 EMR67371.1 - 0.022 14.2 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 PgaD-like protein Ribosomal_S17 PF00366.15 EMR67372.1 - 3.4e-08 33.4 0.7 5.7e-08 32.6 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 eIF2A PF08662.6 EMR67374.1 - 8.4e-37 126.7 2.1 1.1e-33 116.6 0.1 4.1 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 EMR67374.1 - 8.8e-06 25.4 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EMR67374.1 - 0.00017 21.3 0.4 1.8 8.6 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat RRM_6 PF14259.1 EMR67374.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR67374.1 - 0.0017 17.9 0.0 0.0035 16.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EMR67375.1 - 4.1e-44 150.6 0.0 6.2e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EMR67375.1 - 3.9e-41 139.9 0.0 7.6e-41 138.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EMR67375.1 - 6.7e-24 84.3 0.0 8.6e-23 80.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 EMR67375.1 - 1e-06 27.9 0.1 0.0058 16.1 0.0 3.6 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.1 EMR67375.1 - 4e-05 23.1 0.5 0.0001 21.8 0.4 1.6 1 0 0 1 1 1 1 PQQ-like domain APH PF01636.18 EMR67375.1 - 0.0051 16.5 0.5 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EMR67375.1 - 0.02 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EMR67375.1 - 0.026 13.5 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EMR67375.1 - 0.45 9.2 0.0 0.69 8.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cpn60_TCP1 PF00118.19 EMR67376.1 - 2.8e-131 438.4 8.9 3.3e-131 438.2 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1132 PF06575.7 EMR67376.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) TipAS PF07739.8 EMR67377.1 - 0.068 13.4 0.0 0.093 13.0 0.0 1.2 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain FA_desaturase PF00487.19 EMR67378.1 - 4.3e-27 95.1 13.1 6.7e-27 94.5 9.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EMR67378.1 - 6.2e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) RHS_repeat PF05593.9 EMR67380.1 - 0.00058 19.9 58.0 0.21 11.7 0.4 14.7 11 3 5 16 16 16 6 RHS Repeat Gly-zipper_OmpA PF13436.1 EMR67380.1 - 0.72 9.5 5.1 1.7 8.3 3.5 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain RabGAP-TBC PF00566.13 EMR67381.1 - 7.8e-32 110.4 0.0 1.4e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf-C3HC4_3 PF13920.1 EMR67383.1 - 0.0017 18.0 10.3 0.0017 18.0 7.2 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_10 PF00331.15 EMR67385.1 - 3.1e-87 292.5 0.0 3.5e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF1653 PF07866.6 EMR67385.1 - 0.017 15.2 0.0 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1653) AP_endonuc_2 PF01261.19 EMR67385.1 - 0.089 12.0 0.0 0.27 10.4 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel SWIB PF02201.13 EMR67386.1 - 1.4e-26 91.9 1.8 1.6e-26 91.7 0.3 1.9 3 0 0 3 3 3 1 SWIB/MDM2 domain DEK_C PF08766.6 EMR67386.1 - 9.7e-15 54.0 0.9 3.4e-14 52.3 0.3 2.0 2 0 0 2 2 2 1 DEK C terminal domain Interfer-bind PF09294.5 EMR67386.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III DUF2413 PF10310.4 EMR67386.1 - 0.24 10.1 12.4 0.3 9.8 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) BTV_NS2 PF04514.7 EMR67386.1 - 1.2 7.9 10.2 1.6 7.4 7.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Glyco_hydro_3 PF00933.16 EMR67387.1 - 8.5e-78 261.3 0.0 1.2e-77 260.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR67387.1 - 2.7e-58 197.2 0.0 3.9e-58 196.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR67387.1 - 3.6e-22 78.0 0.1 8e-22 76.9 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EMR67387.1 - 1.9e-15 56.8 0.0 3.7e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Phage_tail_X PF05489.7 EMR67387.1 - 0.04 13.4 0.1 0.099 12.1 0.1 1.6 1 0 0 1 1 1 0 Phage Tail Protein X FlxA PF14282.1 EMR67388.1 - 0.0051 16.7 3.1 0.0052 16.7 1.6 1.4 1 1 0 1 1 1 1 FlxA-like protein Ead_Ea22 PF13935.1 EMR67388.1 - 0.0061 16.8 7.2 0.24 11.7 2.7 2.0 1 1 1 2 2 2 2 Ead/Ea22-like protein Med9 PF07544.8 EMR67388.1 - 0.023 14.4 1.1 4.1 7.2 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Sec6 PF06046.8 EMR67388.1 - 0.041 11.9 2.5 0.05 11.6 1.7 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec6 Prefoldin_2 PF01920.15 EMR67388.1 - 0.064 13.0 2.7 2.1 8.1 0.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit AATF-Che1 PF13339.1 EMR67388.1 - 0.098 12.8 5.0 0.13 12.4 3.4 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor ApoO PF09769.4 EMR67388.1 - 0.1 12.3 2.2 0.21 11.2 0.2 2.0 1 1 1 2 2 2 0 Apolipoprotein O Sec8_exocyst PF04048.9 EMR67388.1 - 0.13 11.8 1.6 0.14 11.8 0.3 1.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain SRP-alpha_N PF04086.8 EMR67388.1 - 0.2 10.9 7.7 0.23 10.8 5.3 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Fez1 PF06818.10 EMR67388.1 - 0.46 10.4 7.4 0.56 10.1 5.1 1.1 1 0 0 1 1 1 0 Fez1 THOC7 PF05615.8 EMR67388.1 - 2 8.7 7.5 1.7 8.9 0.6 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 DUF604 PF04646.7 EMR67391.1 - 3.9e-10 39.3 0.0 7.7e-09 35.1 0.0 2.1 1 1 0 2 2 2 1 Protein of unknown function, DUF604 Fringe PF02434.11 EMR67391.1 - 2.5e-08 33.4 0.0 5.3e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Fringe-like Cytokin_check_N PF10407.4 EMR67392.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus Aldolase_II PF00596.16 EMR67394.1 - 5.3e-48 163.0 0.6 6.7e-48 162.7 0.4 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Abhydrolase_3 PF07859.8 EMR67395.1 - 5.8e-31 107.7 0.0 7.7e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMR67395.1 - 1.3e-05 24.1 0.2 4.3e-05 22.4 0.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EMR67395.1 - 0.00015 21.5 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EMR67395.1 - 0.027 12.9 0.0 0.042 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EMR67395.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Glyco_transf_90 PF05686.7 EMR67396.1 - 7.1e-14 51.2 0.2 7.5e-10 38.0 0.0 3.5 3 1 0 3 3 3 3 Glycosyl transferase family 90 DHH PF01368.15 EMR67397.1 - 1.3e-07 31.3 0.0 2.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 DHH family UBA_4 PF14555.1 EMR67397.1 - 0.059 12.9 0.3 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 UBA-like domain Mpv17_PMP22 PF04117.7 EMR67398.1 - 2.6e-17 62.2 3.7 2.6e-17 62.2 2.6 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family UreE_C PF05194.7 EMR67398.1 - 0.084 12.9 2.3 0.45 10.6 1.0 2.1 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain ApbA PF02558.11 EMR67399.1 - 1.6e-24 86.0 0.0 1.8e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EMR67399.1 - 0.02 14.6 2.4 0.16 11.8 1.0 2.1 2 0 0 2 2 2 0 ThiF family Shikimate_DH PF01488.15 EMR67399.1 - 0.061 13.4 1.1 0.25 11.4 0.3 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EMR67399.1 - 0.074 12.9 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EMR67399.1 - 0.096 12.9 0.0 0.16 12.2 0.0 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding CoA_binding PF02629.14 EMR67399.1 - 0.097 13.2 0.4 0.37 11.3 0.3 1.9 1 1 0 1 1 1 0 CoA binding domain FAD_binding_3 PF01494.14 EMR67399.1 - 0.097 11.7 0.4 0.12 11.4 0.3 1.1 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 EMR67399.1 - 0.11 11.3 1.0 0.24 10.1 0.8 1.4 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EMR67399.1 - 0.18 10.6 0.8 0.34 9.7 0.4 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A WD40 PF00400.27 EMR67401.1 - 3.1e-20 71.2 1.0 1.1e-08 34.5 0.4 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 EMR67401.1 - 2e-05 22.9 1.1 0.021 13.0 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EMR67401.1 - 0.00024 20.8 0.1 0.00064 19.4 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EMR67401.1 - 0.0023 16.7 0.1 0.16 10.7 0.0 2.0 1 1 1 2 2 2 2 Nup133 N terminal like Coatomer_WDAD PF04053.9 EMR67401.1 - 0.0078 15.0 0.0 0.026 13.3 0.0 1.6 1 1 1 2 2 2 1 Coatomer WD associated region TFIIIC_delta PF12657.2 EMR67401.1 - 0.028 14.1 0.1 4.6 6.9 0.1 2.3 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Cytochrom_D1 PF02239.11 EMR67401.1 - 0.03 12.6 0.0 0.046 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Phage_term_sma PF07141.6 EMR67401.1 - 0.074 12.6 0.0 0.1 12.1 0.0 1.4 1 1 0 1 1 1 0 Putative bacteriophage terminase small subunit Hira PF07569.6 EMR67401.1 - 0.16 11.1 0.3 1.5 7.9 0.0 2.3 1 1 1 3 3 3 0 TUP1-like enhancer of split Ank_5 PF13857.1 EMR67402.1 - 2e-11 43.7 0.1 5.8e-09 35.9 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR67402.1 - 1.3e-06 28.7 0.1 1.6e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMR67402.1 - 4.7e-05 23.6 0.1 0.00054 20.2 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMR67402.1 - 0.00043 19.9 0.7 0.0079 15.9 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 EMR67402.1 - 0.00052 20.0 2.0 0.0039 17.3 0.2 3.0 3 0 0 3 3 3 1 Ankyrin repeat HWE_HK PF07536.9 EMR67402.1 - 0.004 17.5 0.0 0.03 14.7 0.0 2.1 2 0 0 2 2 2 1 HWE histidine kinase Mito_carr PF00153.22 EMR67403.1 - 2.3e-45 152.2 3.1 1.6e-18 66.1 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Glycos_transf_3 PF00591.16 EMR67404.1 - 9.6e-63 211.9 0.0 1.9e-62 210.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EMR67404.1 - 7e-10 38.3 0.0 1.7e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Vac_ImportDeg PF09783.4 EMR67406.1 - 1.6e-61 206.8 0.6 1.6e-61 206.8 0.4 1.7 2 1 0 2 2 2 1 Vacuolar import and degradation protein DUF3439 PF11921.3 EMR67406.1 - 0.031 14.0 0.1 0.031 14.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) RNA_lig_T4_1 PF09511.5 EMR67407.1 - 4.1e-79 265.1 0.0 6.8e-79 264.4 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 EMR67407.1 - 4.1e-75 252.3 0.0 6.6e-75 251.6 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 EMR67407.1 - 9.4e-55 185.0 0.7 1.7e-54 184.1 0.5 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain 2_5_RNA_ligase2 PF13563.1 EMR67407.1 - 0.049 13.3 0.0 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily SGL PF08450.7 EMR67408.1 - 7.3e-06 25.5 0.0 0.00045 19.6 0.0 2.3 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region ABC2_membrane PF01061.19 EMR67409.1 - 1.9e-28 99.0 33.1 1.3e-22 80.0 11.9 2.9 2 1 1 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EMR67409.1 - 7e-12 44.9 4.4 8.7e-12 44.6 0.0 3.0 3 0 0 3 3 3 1 CDR ABC transporter ABC_tran PF00005.22 EMR67409.1 - 3.1e-07 30.7 0.1 5.6e-07 29.9 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 EMR67409.1 - 5.6e-06 25.8 0.1 9.4e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EMR67409.1 - 0.0022 17.4 0.4 0.0033 16.8 0.3 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EMR67409.1 - 0.0023 17.4 0.1 0.0054 16.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EMR67409.1 - 0.0027 16.8 0.0 0.0043 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EMR67409.1 - 0.014 15.7 0.1 0.037 14.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMR67409.1 - 0.02 14.8 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 EMR67409.1 - 0.023 14.6 0.2 0.038 13.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMR67409.1 - 0.041 14.1 0.1 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMR67409.1 - 0.053 14.3 0.1 0.11 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMR67409.1 - 0.079 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EMR67409.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EMR67409.1 - 0.15 11.7 0.2 0.34 10.5 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Ribosomal_L10 PF00466.15 EMR67410.1 - 0.00051 19.9 0.0 0.0031 17.4 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L10 TPR_11 PF13414.1 EMR67411.1 - 7.6e-05 22.2 13.8 0.19 11.3 1.2 5.5 5 1 0 5 5 5 3 TPR repeat TPR_14 PF13428.1 EMR67411.1 - 0.0021 18.5 5.7 1.7 9.4 0.5 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat GreA_GreB_N PF03449.10 EMR67412.1 - 0.22 11.5 6.2 20 5.2 1.2 3.3 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal Occludin_ELL PF07303.8 EMR67412.1 - 0.68 10.6 5.0 0.36 11.5 1.0 2.1 2 0 0 2 2 2 0 Occludin homology domain UPF0020 PF01170.13 EMR67413.1 - 3.9e-11 42.8 0.0 7.5e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EMR67413.1 - 2.1e-06 27.7 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF4477 PF14780.1 EMR67413.1 - 0.18 11.1 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) ChAPs PF09295.5 EMR67415.1 - 1.1e-159 531.4 0.0 1.5e-159 531.0 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 EMR67415.1 - 2.1e-07 30.9 0.7 0.7 10.6 0.2 5.5 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMR67415.1 - 4.7e-07 29.1 0.5 0.077 12.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMR67415.1 - 1.1e-06 28.1 1.2 0.011 15.4 0.1 3.6 4 0 0 4 4 4 2 TPR repeat TPR_8 PF13181.1 EMR67415.1 - 3.4e-05 23.3 0.3 0.45 10.4 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMR67415.1 - 6.8e-05 22.4 1.1 0.11 12.5 1.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMR67415.1 - 7.1e-05 22.5 0.1 0.094 12.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMR67415.1 - 0.00068 19.9 0.1 1.4 9.3 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EMR67415.1 - 0.00088 19.3 1.8 0.37 10.9 0.0 3.6 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EMR67415.1 - 0.0013 18.2 0.5 2 8.1 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMR67415.1 - 0.0045 16.8 0.8 9 6.3 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMR67415.1 - 0.015 15.6 0.7 31 5.3 0.0 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF2007 PF09413.5 EMR67415.1 - 0.075 12.8 0.0 0.54 10.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2007) PPR_3 PF13812.1 EMR67415.1 - 0.089 13.1 0.0 24 5.5 0.0 3.7 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TPR_16 PF13432.1 EMR67415.1 - 0.11 13.2 2.3 4.9 7.9 0.2 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Vg_Tdu PF07545.9 EMR67415.1 - 0.12 11.8 0.0 0.47 9.9 0.0 2.0 2 0 0 2 2 2 0 Vestigial/Tondu family AdoHcyase PF05221.12 EMR67417.1 - 7.2e-136 451.4 0.2 8.3e-136 451.2 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EMR67417.1 - 1e-83 279.0 3.2 1.6e-83 278.3 2.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EMR67417.1 - 1.9e-05 23.8 0.2 4.3e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EMR67417.1 - 0.021 14.1 0.4 0.04 13.3 0.3 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ELFV_dehydrog PF00208.16 EMR67417.1 - 0.042 13.4 0.1 0.074 12.6 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Mago_nashi PF02792.9 EMR67418.1 - 3.1e-44 150.1 0.1 3.3e-44 150.0 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein JAB PF01398.16 EMR67419.1 - 1.7e-05 24.5 0.2 0.00079 19.1 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Sec39 PF08314.6 EMR67420.1 - 3e-137 458.5 2.3 1.5e-56 191.7 1.4 3.1 1 1 2 3 3 3 3 Secretory pathway protein Sec39 MFS_1 PF07690.11 EMR67421.1 - 8.5e-29 100.3 23.3 8.5e-29 100.3 16.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1218 PF06749.7 EMR67421.1 - 0.0068 16.8 0.9 0.014 15.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1218) DUF3169 PF11368.3 EMR67421.1 - 0.048 12.8 1.3 0.82 8.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) Med5 PF08689.5 EMR67422.1 - 3.7e-51 173.9 0.0 4.2e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 TIP120 PF08623.5 EMR67422.1 - 0.16 11.5 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) SRP72 PF08492.7 EMR67423.1 - 6.6e-16 58.4 1.7 1.8e-15 57.0 1.2 1.7 1 0 0 1 1 1 1 SRP72 RNA-binding domain Apc3 PF12895.2 EMR67423.1 - 1.6e-05 24.9 1.4 0.0016 18.5 0.6 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EMR67423.1 - 0.0024 18.1 11.8 1.9 8.8 1.5 5.8 4 2 2 6 6 6 1 Tetratricopeptide repeat SPO22 PF08631.5 EMR67423.1 - 0.0025 16.9 0.2 0.0085 15.2 0.0 1.9 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.1 EMR67423.1 - 0.025 15.1 20.8 11 7.0 0.0 7.7 5 3 3 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 EMR67423.1 - 0.047 13.6 15.0 1.5 8.9 0.3 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4633 PF15464.1 EMR67423.1 - 0.053 13.3 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) TPR_16 PF13432.1 EMR67423.1 - 0.6 10.8 19.8 0.28 11.9 1.6 4.9 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.7 EMR67423.1 - 1.6 8.6 4.9 13 5.7 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMR67423.1 - 3.7 7.3 8.5 4.9 6.9 0.2 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Exo_endo_phos PF03372.18 EMR67424.1 - 1.2e-10 41.7 0.0 2.2e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_60s PF00428.14 EMR67424.1 - 0.14 12.5 0.3 0.14 12.5 0.2 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein SNARE PF05739.14 EMR67425.1 - 2e-19 69.0 1.6 1.1e-18 66.5 0.7 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EMR67425.1 - 5.4e-08 32.9 0.2 5.4e-08 32.9 0.2 2.6 2 1 0 2 2 2 1 Syntaxin DUF4611 PF15387.1 EMR67425.1 - 0.026 14.6 0.9 0.094 12.8 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) P12 PF12669.2 EMR67425.1 - 0.31 11.2 2.3 0.67 10.2 1.6 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family MCPsignal PF00015.16 EMR67425.1 - 0.44 10.0 13.6 0.3 10.5 1.2 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3391 PF11871.3 EMR67425.1 - 4.9 7.3 8.4 0.65 10.2 0.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) DUF1793 PF08760.6 EMR67426.1 - 1.6e-47 161.5 0.3 1.9e-46 158.0 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF1793) NAD_binding_1 PF00175.16 EMR67427.1 - 7.7e-06 26.4 0.0 0.0098 16.4 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMR67427.1 - 0.0015 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EMR67427.1 - 0.0072 16.2 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain EF-hand_1 PF00036.27 EMR67428.1 - 1.6e-37 123.9 13.6 1.2e-09 36.7 0.6 4.8 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 EMR67428.1 - 2e-33 114.2 7.0 4.9e-17 61.8 1.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EMR67428.1 - 1.2e-30 104.8 13.9 8.4e-16 57.3 0.6 3.9 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.1 EMR67428.1 - 6e-27 91.0 7.9 1.3e-09 37.1 0.1 4.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EMR67428.1 - 2.5e-24 83.4 7.6 1.5e-06 27.2 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EMR67428.1 - 3.2e-14 52.5 0.3 2.4e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EMR67428.1 - 1.3e-08 34.4 1.9 0.0029 17.3 0.1 2.3 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 EMR67428.1 - 4.7e-08 32.5 0.0 0.024 14.2 0.0 3.3 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 EMR67428.1 - 8.2e-08 32.2 0.3 0.01 15.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 EMR67428.1 - 0.00014 21.6 0.1 0.31 10.7 0.0 2.2 2 0 0 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EMR67428.1 - 0.0005 19.6 0.3 0.09 12.3 0.0 2.9 1 1 3 4 4 4 1 Caleosin related protein EFhand_Ca_insen PF08726.5 EMR67428.1 - 0.00094 19.1 2.6 0.035 14.0 0.3 3.1 2 2 0 2 2 2 1 Ca2+ insensitive EF hand RNA_pol_Rpb4 PF03874.11 EMR67428.1 - 0.001 19.0 0.3 0.48 10.4 0.1 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb4 Tenui_NCP PF04876.7 EMR67428.1 - 0.0031 17.0 0.1 0.21 11.0 0.0 2.3 1 1 0 2 2 2 1 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 EMR67428.1 - 0.0059 16.9 1.1 2.2 8.6 0.0 2.5 1 1 1 2 2 2 2 Toprim-like DUF3349 PF11829.3 EMR67428.1 - 0.036 14.5 0.4 9 6.8 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3349) HMG_box_2 PF09011.5 EMR67428.1 - 0.12 12.7 0.0 3.4 8.0 0.0 2.5 2 0 0 2 2 2 0 HMG-box domain EF-hand_10 PF14788.1 EMR67428.1 - 0.15 11.7 1.5 0.94 9.1 0.1 2.8 2 1 1 3 3 3 0 EF hand PB1 PF00564.19 EMR67428.1 - 0.57 9.8 2.3 44 3.8 0.1 3.3 2 1 1 3 3 3 0 PB1 domain WD40 PF00400.27 EMR67430.1 - 1.5e-19 69.0 5.0 7.1e-08 32.0 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 EMR67430.1 - 0.0092 14.1 0.0 0.015 13.4 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 COX7a PF02238.10 EMR67431.1 - 0.58 9.9 4.0 0.26 11.0 0.7 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa Glyco_hydro_47 PF01532.15 EMR67432.1 - 5.6e-161 536.2 0.0 6.5e-161 535.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TPR_11 PF13414.1 EMR67435.1 - 2.3e-10 39.9 0.7 1.3e-06 27.9 0.2 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMR67435.1 - 4.4e-08 32.4 7.9 0.0001 21.8 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMR67435.1 - 2.1e-05 24.3 1.7 0.0008 19.2 0.4 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMR67435.1 - 2.4e-05 23.7 0.6 0.042 13.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR67435.1 - 5.2e-05 23.5 1.3 0.00043 20.5 0.9 2.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMR67435.1 - 0.00034 21.2 2.7 0.00034 21.2 1.8 2.7 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMR67435.1 - 0.0022 18.4 10.1 0.038 14.6 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMR67435.1 - 0.0036 16.9 0.0 0.086 12.6 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMR67435.1 - 0.024 15.0 1.1 0.76 10.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMR67435.1 - 0.15 11.9 6.9 1.6 8.6 0.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMR67435.1 - 0.59 10.7 11.2 0.6 10.7 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Med5 PF08689.5 EMR67436.1 - 2.7e-29 101.5 0.0 2.9e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 SSF PF00474.12 EMR67436.1 - 0.0073 14.9 0.6 0.0089 14.7 0.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family RRM_1 PF00076.17 EMR67437.1 - 1.1e-19 69.8 0.0 1.6e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR67437.1 - 9.9e-16 57.4 0.0 1.5e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR67437.1 - 2.1e-11 43.4 0.0 2.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_8 PF01501.15 EMR67439.1 - 3.1e-21 75.8 0.1 1e-20 74.1 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EMR67439.1 - 0.0052 16.1 0.0 0.0092 15.3 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative RapA_C PF12137.3 EMR67440.1 - 0.052 12.3 0.2 0.073 11.9 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Nop14 PF04147.7 EMR67440.1 - 0.25 9.2 5.6 0.23 9.3 3.9 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EMR67440.1 - 3 7.3 12.0 5.5 6.4 8.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin Hydrolase_4 PF12146.3 EMR67441.1 - 1.2e-21 76.2 0.0 2.8e-21 75.1 0.0 1.6 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EMR67441.1 - 3.5e-20 72.8 2.0 4.4e-20 72.5 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR67441.1 - 2.4e-16 59.8 0.0 5.4e-16 58.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR67441.1 - 4.2e-06 26.1 0.3 0.0038 16.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EMR67441.1 - 0.0001 21.9 0.5 0.00027 20.5 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2786 PF10979.3 EMR67441.1 - 0.094 12.4 0.4 0.18 11.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) PGAP1 PF07819.8 EMR67441.1 - 0.18 11.3 0.0 0.39 10.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Adaptin_N PF01602.15 EMR67442.1 - 1e-128 429.9 0.6 1.3e-128 429.6 0.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EMR67442.1 - 5.2e-20 71.8 0.0 1.1e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EMR67442.1 - 7.1e-07 29.4 0.3 0.081 13.2 0.0 4.4 3 2 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EMR67442.1 - 0.00049 20.5 0.5 5.2 7.6 0.0 5.1 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 EMR67442.1 - 0.0009 19.1 0.2 0.023 14.5 0.1 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EMR67442.1 - 0.0022 17.9 1.7 16 5.8 0.0 5.4 5 1 1 6 6 6 1 HEAT repeat TIP120 PF08623.5 EMR67442.1 - 0.011 15.2 1.1 0.062 12.8 0.1 2.7 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) API5 PF05918.6 EMR67442.1 - 0.012 14.1 0.0 0.022 13.2 0.0 1.4 1 1 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Arm PF00514.18 EMR67442.1 - 0.044 13.6 0.2 96 3.0 0.0 5.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF1897 PF09005.5 EMR67443.1 - 0.24 10.8 3.7 0.47 9.9 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) zf-C2H2_4 PF13894.1 EMR67444.1 - 1.8e-06 27.8 14.0 0.072 13.4 0.0 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EMR67444.1 - 7.3e-05 22.8 21.6 0.9 10.0 0.0 4.8 4 1 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EMR67444.1 - 0.0014 18.4 1.6 0.06 13.2 0.4 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 EMR67444.1 - 0.46 10.7 3.5 5.2 7.4 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type IBR PF01485.16 EMR67444.1 - 1.4 8.8 8.2 4.6 7.1 0.1 3.0 1 1 1 2 2 2 0 IBR domain PPR_3 PF13812.1 EMR67445.1 - 0.00034 20.6 0.1 2.9 8.3 0.0 4.2 3 0 0 3 3 3 2 Pentatricopeptide repeat domain Nitroreductase PF00881.19 EMR67446.1 - 3e-24 85.6 0.0 5.1e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Nitroreductase family TRAP_alpha PF03896.11 EMR67447.1 - 4.8e-11 42.1 1.1 2.1e-10 40.0 0.7 2.0 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF4352 PF11611.3 EMR67447.1 - 0.069 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) ABC_membrane PF00664.18 EMR67448.1 - 8e-49 166.5 11.1 1.1e-48 165.9 7.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EMR67448.1 - 4.3e-35 121.0 0.0 1.4e-34 119.2 0.0 2.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EMR67448.1 - 1.1e-05 24.8 0.0 0.00043 19.5 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMR67448.1 - 2.2e-05 24.5 0.0 5.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EMR67448.1 - 0.00028 20.9 0.1 0.62 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMR67448.1 - 0.002 18.2 0.2 0.024 14.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EMR67448.1 - 0.0025 17.3 0.2 0.0063 16.0 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EMR67448.1 - 0.0039 17.9 0.1 0.014 16.2 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMR67448.1 - 0.019 15.1 0.5 0.87 9.7 0.4 2.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EMR67448.1 - 0.023 14.6 0.7 0.2 11.6 0.5 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EMR67448.1 - 0.028 14.1 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.4 EMR67448.1 - 0.043 12.3 0.3 0.089 11.3 0.0 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.1 EMR67448.1 - 0.045 13.1 0.3 0.26 10.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EMR67448.1 - 0.1 12.0 0.6 0.68 9.3 0.2 2.3 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EMR67448.1 - 0.13 11.7 0.8 1 8.7 0.0 2.4 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.1 EMR67448.1 - 0.17 12.1 2.1 0.31 11.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain CTD_bind PF04818.8 EMR67449.1 - 3.7e-20 71.9 1.0 6e-20 71.2 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.3 EMR67449.1 - 0.035 13.7 0.1 0.059 13.0 0.1 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Clathrin_lg_ch PF01086.12 EMR67450.1 - 4.7e-68 229.4 7.2 5.4e-68 229.2 5.0 1.0 1 0 0 1 1 1 1 Clathrin light chain rve_3 PF13683.1 EMR67450.1 - 0.11 12.0 0.5 0.23 11.0 0.3 1.5 1 0 0 1 1 1 0 Integrase core domain DUF4407 PF14362.1 EMR67450.1 - 3.2 6.6 6.0 0.76 8.6 1.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pept_tRNA_hydro PF01195.14 EMR67451.1 - 5.6e-27 94.4 0.0 7.4e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase AIG2 PF06094.7 EMR67454.1 - 0.0012 19.3 0.0 0.0032 17.9 0.0 1.9 1 1 0 1 1 1 1 AIG2-like family WD40 PF00400.27 EMR67456.1 - 6.4e-20 70.2 19.6 3.1e-08 33.1 0.0 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 EMR67456.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity RRM_5 PF13893.1 EMR67458.1 - 0.00011 22.0 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR67458.1 - 0.0037 16.8 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR67458.1 - 0.038 13.9 0.1 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Herpes_capsid PF06112.6 EMR67458.1 - 0.4 10.7 4.4 0.51 10.3 3.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF846 PF05832.7 EMR67459.1 - 6.6e-53 178.2 7.4 7.9e-53 177.9 5.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4191 PF13829.1 EMR67459.1 - 0.42 9.6 1.8 5.8 5.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF3445 PF11927.3 EMR67460.1 - 3.4e-79 265.7 0.0 4.4e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) SopA PF13981.1 EMR67460.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 SopA-like central domain Cupin_2 PF07883.6 EMR67461.1 - 1.8e-09 36.9 0.3 3.2e-09 36.1 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EMR67461.1 - 0.00033 19.9 0.0 0.00065 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 EMR67461.1 - 0.0027 17.3 0.1 0.004 16.8 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 EMR67461.1 - 0.0035 16.9 0.1 0.0045 16.6 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase EutQ PF06249.7 EMR67461.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ FdtA PF05523.6 EMR67461.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal DUF4191 PF13829.1 EMR67462.1 - 4.9 6.2 5.7 2 7.4 2.4 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Glyco_hydro_31 PF01055.21 EMR67463.1 - 6.5e-92 308.6 0.1 8.4e-92 308.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMR67463.1 - 7e-13 48.2 0.0 2.6e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like p450 PF00067.17 EMR67464.1 - 1.5e-05 23.7 0.0 0.014 13.9 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 Zn_clus PF00172.13 EMR67465.1 - 3.5e-09 36.4 7.9 6.9e-09 35.4 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMR67465.1 - 0.00041 19.3 0.5 0.00096 18.1 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Mito_fiss_reg PF05308.6 EMR67465.1 - 0.059 12.7 0.1 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator adh_short PF00106.20 EMR67466.1 - 2.6e-18 66.4 0.3 3.8e-18 65.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR67466.1 - 4e-10 39.6 0.2 5.5e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR67466.1 - 0.0006 19.6 0.0 0.00096 18.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMR67466.1 - 0.0021 18.0 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding TIR-like PF10137.4 EMR67466.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Epimerase PF01370.16 EMR67466.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Prp19 PF08606.6 EMR67466.1 - 0.047 13.4 0.1 0.098 12.3 0.1 1.5 1 0 0 1 1 1 0 Prp19/Pso4-like THF_DHG_CYH_C PF02882.14 EMR67466.1 - 0.07 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EMR67466.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 EMR67467.1 - 2.3e-31 108.7 31.0 2.3e-31 108.7 21.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Herpes_US9 PF06072.6 EMR67467.1 - 0.017 14.9 1.2 0.056 13.2 0.0 2.6 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF2500 PF10694.4 EMR67467.1 - 0.081 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) FAD_binding_4 PF01565.18 EMR67470.1 - 2.8e-17 62.4 0.9 2.8e-17 62.4 0.6 1.9 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.23 EMR67471.1 - 4e-06 26.5 0.0 0.067 13.0 0.0 2.7 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain HET PF06985.6 EMR67472.1 - 2.5e-13 50.3 0.4 5.5e-13 49.2 0.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF747 PF05346.6 EMR67473.1 - 2.1e-42 145.3 0.0 2.4e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic membrane protein family WBP-1 PF11669.3 EMR67473.1 - 0.052 13.6 0.2 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 WW domain-binding protein 1 Myc_target_1 PF15179.1 EMR67473.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Myc target protein 1 Peptidase_M16 PF00675.15 EMR67475.1 - 8.3e-16 58.0 0.0 1.6e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EMR67475.1 - 1.3e-13 51.0 0.0 1e-12 48.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain LEA_3 PF03242.8 EMR67475.1 - 0.8 9.9 3.6 0.55 10.5 0.4 2.3 2 0 0 2 2 2 0 Late embryogenesis abundant protein DsbC PF11412.3 EMR67476.1 - 0.029 14.1 0.2 0.63 9.8 0.1 2.2 2 0 0 2 2 2 0 Disulphide bond corrector protein DsbC Dioxygenase_C PF00775.16 EMR67477.1 - 6.1e-07 28.8 0.0 1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Mak10 PF04112.8 EMR67478.1 - 2.8e-49 166.5 0.0 4.3e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Cnd2 PF05786.9 EMR67478.1 - 5.1 5.4 4.0 7 5.0 2.8 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Mito_carr PF00153.22 EMR67480.1 - 1.8e-46 155.7 0.5 4.2e-16 58.4 0.2 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein RAB3GAP2_C PF14656.1 EMR67480.1 - 0.066 11.3 0.0 0.092 10.8 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus UcrQ PF02939.11 EMR67480.1 - 0.075 12.8 0.1 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 UcrQ family ATP-synt_Eps PF04627.8 EMR67481.1 - 3.1e-16 58.6 5.3 7e-16 57.5 0.2 2.5 3 0 0 3 3 3 2 Mitochondrial ATP synthase epsilon chain CorA PF01544.13 EMR67482.1 - 3.1e-06 26.4 0.3 3.1e-06 26.4 0.2 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein RRM_3 PF08777.6 EMR67482.1 - 0.13 12.1 0.7 0.24 11.2 0.5 1.4 1 0 0 1 1 1 0 RNA binding motif Beta-lactamase PF00144.19 EMR67483.1 - 2.7e-33 115.3 0.0 2e-32 112.5 0.0 2.2 1 1 1 2 2 2 1 Beta-lactamase Ecm33 PF12454.3 EMR67483.1 - 1.3 8.9 3.7 0.64 9.9 0.1 2.2 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Lactamase_B PF00753.22 EMR67484.1 - 1.1e-06 28.4 6.2 2.7e-05 23.9 0.1 2.4 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMR67484.1 - 0.00081 18.9 0.2 0.0012 18.3 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain WSC PF01822.14 EMR67485.1 - 7.7e-05 22.5 19.7 9.9e-05 22.1 1.0 4.2 4 0 0 4 4 4 2 WSC domain Peptidase_M28 PF04389.12 EMR67486.1 - 6.7e-26 91.1 0.0 1e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMR67486.1 - 5.1e-14 51.8 0.1 9.4e-14 50.9 0.1 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EMR67486.1 - 5e-05 22.8 0.0 8.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Mis14 PF08641.7 EMR67487.1 - 9.8e-06 25.6 0.3 0.00013 22.0 0.0 2.5 3 0 0 3 3 3 1 Kinetochore protein Mis14 like Sec7 PF01369.15 EMR67488.1 - 1.7e-43 148.5 0.1 3.2e-43 147.6 0.1 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EMR67488.1 - 9.2e-19 67.7 0.0 2.4e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain SPT2 PF08243.6 EMR67488.1 - 0.014 15.7 0.7 0.03 14.6 0.5 1.6 1 0 0 1 1 1 0 SPT2 chromatin protein Prefoldin PF02996.12 EMR67491.1 - 3.8e-34 116.9 0.7 8.8e-34 115.7 0.1 1.7 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 EMR67491.1 - 0.0003 20.4 1.0 0.0056 16.4 0.1 2.7 1 1 0 2 2 2 1 Prefoldin subunit Filament PF00038.16 EMR67491.1 - 0.00068 19.1 2.8 0.012 15.1 0.4 1.9 2 0 0 2 2 2 2 Intermediate filament protein DUF4201 PF13870.1 EMR67491.1 - 0.026 13.9 0.9 0.56 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) HR1 PF02185.11 EMR67491.1 - 0.099 12.3 0.2 0.84 9.4 0.0 2.2 2 1 0 2 2 2 0 Hr1 repeat DUF4200 PF13863.1 EMR67491.1 - 0.44 10.5 3.6 6.3 6.7 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Folliculin PF11704.3 EMR67492.1 - 1e-05 25.2 0.0 3.3e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Mid2 PF04478.7 EMR67493.1 - 0.0019 17.6 0.0 0.0019 17.6 0.0 2.4 2 1 0 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 EMR67493.1 - 0.0054 16.0 4.0 0.013 14.8 2.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain ADH_N PF08240.7 EMR67494.1 - 4.2e-23 81.1 5.4 6.9e-23 80.4 3.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR67494.1 - 2.1e-16 59.6 0.0 3.4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR67494.1 - 2.1e-09 38.3 0.0 4.6e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zinc-ribbons_6 PF07191.7 EMR67494.1 - 0.029 14.1 0.9 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbons 2-Hacid_dh_C PF02826.14 EMR67494.1 - 0.074 12.1 0.2 0.13 11.3 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AAA PF00004.24 EMR67496.1 - 3.1e-45 153.5 0.1 1.2e-44 151.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMR67496.1 - 4.2e-09 36.2 0.3 1.5e-08 34.4 0.1 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMR67496.1 - 5.5e-08 32.9 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EMR67496.1 - 4.8e-07 29.9 0.0 1.5e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMR67496.1 - 8.3e-07 29.2 0.6 0.00027 21.0 0.4 2.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EMR67496.1 - 3.7e-06 26.0 0.0 7e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EMR67496.1 - 0.00021 21.2 0.1 0.00097 19.0 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 EMR67496.1 - 0.0005 20.0 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMR67496.1 - 0.00055 19.0 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EMR67496.1 - 0.00057 19.5 0.3 0.056 13.0 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 EMR67496.1 - 0.0011 19.8 0.0 0.0051 17.6 0.0 2.1 3 0 0 3 3 1 1 AAA domain RNA_helicase PF00910.17 EMR67496.1 - 0.0011 19.0 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 EMR67496.1 - 0.0013 17.5 0.0 0.0023 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EMR67496.1 - 0.0014 18.3 0.2 0.0037 16.9 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 EMR67496.1 - 0.0021 17.7 0.0 0.0074 16.0 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_11 PF13086.1 EMR67496.1 - 0.0038 16.8 0.3 0.015 14.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMR67496.1 - 0.0042 16.1 0.1 0.012 14.7 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.6 EMR67496.1 - 0.0043 16.6 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EMR67496.1 - 0.0054 16.4 0.5 0.052 13.2 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase UPF0079 PF02367.12 EMR67496.1 - 0.0055 16.3 0.0 0.046 13.3 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EMR67496.1 - 0.0056 16.5 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EMR67496.1 - 0.0069 15.5 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EMR67496.1 - 0.0072 15.7 1.0 0.075 12.4 0.1 2.4 1 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EMR67496.1 - 0.013 15.1 0.7 0.03 13.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EMR67496.1 - 0.013 14.9 0.3 0.03 13.7 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 EMR67496.1 - 0.014 15.7 0.7 0.85 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMR67496.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 EMR67496.1 - 0.032 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_18 PF13238.1 EMR67496.1 - 0.033 14.4 0.0 0.1 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EMR67496.1 - 0.038 13.1 1.3 0.47 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.21 EMR67496.1 - 0.05 13.0 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 EMR67496.1 - 0.07 11.9 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Viral_Hsp90 PF03225.9 EMR67496.1 - 0.081 11.2 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Sigma54_activ_2 PF14532.1 EMR67496.1 - 0.089 12.8 0.1 0.41 10.6 0.0 2.2 2 1 0 2 2 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EMR67496.1 - 0.14 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EMR67496.1 - 0.17 10.7 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF427 PF04248.7 EMR67497.1 - 5.7e-31 106.0 0.0 4.8e-22 77.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF427) FAD_binding_3 PF01494.14 EMR67498.1 - 2e-23 83.0 0.0 2.6e-12 46.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EMR67498.1 - 7.8e-08 32.6 0.0 5e-07 29.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR67498.1 - 5.9e-06 26.2 0.4 3.4e-05 23.7 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR67498.1 - 0.00014 20.8 0.3 0.0051 15.7 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR67498.1 - 0.00015 20.4 0.1 0.0055 15.2 0.0 2.7 3 1 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 EMR67498.1 - 0.0012 19.2 0.2 0.034 14.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR67498.1 - 0.0015 17.6 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EMR67498.1 - 0.0018 18.0 0.3 0.22 11.3 0.1 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EMR67498.1 - 0.0043 15.9 0.6 0.042 12.6 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain TrkA_N PF02254.13 EMR67498.1 - 0.015 15.2 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain K_oxygenase PF13434.1 EMR67498.1 - 0.027 13.3 0.0 0.1 11.4 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EMR67498.1 - 0.056 12.3 2.3 0.073 11.9 0.1 2.3 2 2 1 3 3 3 0 Lycopene cyclase protein ApbA PF02558.11 EMR67498.1 - 0.065 12.6 0.2 0.38 10.1 0.2 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Ala_racemase_N PF01168.15 EMR67499.1 - 4.6e-28 98.2 0.3 5.5e-28 98.0 0.2 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.1 EMR67499.1 - 1.5e-16 60.3 0.0 3e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Glyco_trans_4_4 PF13579.1 EMR67499.1 - 0.0018 18.4 0.2 0.02 15.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain SDH_alpha PF03313.10 EMR67499.1 - 0.0092 15.0 1.2 1.3 8.0 0.0 2.2 2 0 0 2 2 2 2 Serine dehydratase alpha chain ArgK PF03308.11 EMR67499.1 - 0.037 12.8 0.9 0.7 8.6 0.0 2.2 2 0 0 2 2 2 0 ArgK protein GTP_CH_N PF12471.3 EMR67499.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.6 1 1 0 1 1 1 0 GTP cyclohydrolase N terminal CRAL_TRIO PF00650.15 EMR67500.1 - 4.7e-31 107.4 0.0 8.1e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EMR67500.1 - 5.2e-09 36.0 1.2 7.5e-09 35.5 0.2 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EMR67500.1 - 0.00034 20.5 0.0 0.0027 17.6 0.0 2.1 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain AA_permease PF00324.16 EMR67501.1 - 1.8e-101 339.8 37.9 5.6e-80 268.9 13.6 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EMR67501.1 - 1.6e-21 76.3 32.8 1.1e-18 67.0 14.6 2.0 1 1 1 2 2 2 2 Amino acid permease Y_phosphatase PF00102.22 EMR67502.1 - 2.4e-44 151.4 0.0 2.7e-43 148.0 0.0 2.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMR67502.1 - 7.4e-07 29.3 0.0 1.3e-05 25.3 0.0 2.8 3 0 0 3 3 3 1 Inositol hexakisphosphate DSPc PF00782.15 EMR67502.1 - 0.00052 19.5 0.0 0.0016 18.0 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EMR67502.1 - 0.011 15.9 0.0 0.029 14.6 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family HSP20 PF00011.16 EMR67503.1 - 3.3e-11 42.9 0.0 5.4e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PhoD PF09423.5 EMR67504.1 - 1.9e-05 23.4 0.7 0.00033 19.3 0.1 2.0 2 0 0 2 2 2 2 PhoD-like phosphatase DSPc PF00782.15 EMR67505.1 - 2.1e-16 59.7 0.0 5.5e-16 58.3 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DSPn PF14671.1 EMR67505.1 - 2e-12 47.3 0.0 2.9e-10 40.2 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half Y_phosphatase PF00102.22 EMR67505.1 - 1e-06 28.3 0.0 1.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pacs-1 PF10254.4 EMR67505.1 - 0.0092 14.6 1.2 0.015 13.9 0.8 1.2 1 0 0 1 1 1 1 PACS-1 cytosolic sorting protein PTPlike_phytase PF14566.1 EMR67505.1 - 0.033 14.2 0.0 0.083 12.9 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EMR67505.1 - 0.23 11.6 1.2 0.31 11.2 0.1 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family p450 PF00067.17 EMR67506.1 - 3.4e-56 190.6 0.0 5.2e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 OmdA PF13376.1 EMR67507.1 - 8.8e-15 54.1 0.2 8.2e-14 51.0 0.1 2.5 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated Gag_p12 PF01141.13 EMR67507.1 - 0.049 13.7 0.4 0.1 12.7 0.3 1.5 1 0 0 1 1 1 0 Gag polyprotein, inner coat protein p12 DUF4648 PF15505.1 EMR67507.1 - 0.26 11.4 3.4 0.14 12.3 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) Mito_carr PF00153.22 EMR67510.1 - 1.8e-39 133.3 7.0 7.2e-17 60.8 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NPV_P10 PF05531.7 EMR67511.1 - 0.072 13.3 0.3 0.16 12.2 0.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.20 EMR67512.1 - 7.6e-69 231.7 0.0 1.1e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR67512.1 - 4.4e-41 140.6 0.0 6.6e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR67512.1 - 2.9e-10 39.5 0.0 4.2e-08 32.5 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 EMR67512.1 - 0.002 17.2 0.0 0.0047 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMR67512.1 - 0.0044 16.7 2.9 0.11 12.2 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family CD20 PF04103.10 EMR67513.1 - 0.081 12.8 8.2 0.14 12.0 0.2 2.8 2 1 0 2 2 2 0 CD20-like family PSII_BNR PF14870.1 EMR67514.1 - 5.4e-08 32.1 6.8 1.5e-05 24.1 0.1 3.7 1 1 1 4 4 4 2 Photosynthesis system II assembly factor YCF48 BNR PF02012.15 EMR67514.1 - 0.00066 19.1 30.7 0.19 11.6 0.8 6.4 7 0 0 7 7 7 5 BNR/Asp-box repeat BNR_2 PF13088.1 EMR67514.1 - 0.015 14.5 5.5 0.46 9.7 0.7 3.3 1 1 1 2 2 2 0 BNR repeat-like domain p450 PF00067.17 EMR67515.1 - 1.4e-49 168.8 0.0 2.1e-49 168.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_20 PF00982.16 EMR67516.1 - 8.4e-197 654.3 0.0 9.7e-197 654.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 EMR67516.1 - 0.012 15.0 0.1 1.3 8.4 0.0 2.5 2 1 0 2 2 2 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EMR67516.1 - 0.034 13.6 0.7 0.087 12.2 0.2 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain IBR PF01485.16 EMR67517.1 - 9e-14 51.0 13.2 1.9e-07 30.8 1.6 2.3 2 0 0 2 2 2 2 IBR domain zf-AN1 PF01428.11 EMR67517.1 - 0.024 14.4 3.1 0.024 14.4 2.1 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EMR67517.1 - 0.055 13.6 9.2 0.63 10.3 1.0 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain U79_P34 PF03064.11 EMR67517.1 - 0.19 11.2 8.1 0.28 10.6 5.6 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1675 PF07897.6 EMR67517.1 - 0.27 11.0 4.5 0.45 10.3 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CAF-1_p150 PF11600.3 EMR67517.1 - 1.1 8.5 25.6 1.6 8.0 17.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Borrelia_P83 PF05262.6 EMR67517.1 - 1.3 7.2 10.5 1.4 7.0 7.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Caldesmon PF02029.10 EMR67517.1 - 1.8 6.9 19.7 2.2 6.5 13.7 1.1 1 0 0 1 1 1 0 Caldesmon Atg14 PF10186.4 EMR67517.1 - 2.7 6.8 12.4 3.7 6.4 8.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EMR67517.1 - 7.8 5.4 14.2 10 5.0 9.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_11 PF13086.1 EMR67517.1 - 9.9 5.6 6.6 13 5.2 4.6 1.1 1 0 0 1 1 1 0 AAA domain CENP-T PF15511.1 EMR67518.1 - 1.2e-96 324.4 19.7 1.2e-96 324.4 13.7 1.8 2 1 0 2 2 2 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EMR67518.1 - 2.5e-08 33.9 0.1 5.1e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EMR67518.1 - 4.8e-05 23.3 0.0 9.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMR67518.1 - 0.00011 22.1 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EMR67518.1 - 0.034 13.8 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated dsDNA_bind PF01984.15 EMR67519.1 - 1.4e-28 99.0 10.8 1.5e-28 98.8 7.5 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 EMR67519.1 - 0.0074 16.5 1.5 0.011 15.9 0.4 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4615) Sas10_Utp3 PF04000.10 EMR67520.1 - 3.1e-17 62.5 0.2 3.1e-17 62.5 0.2 2.1 2 1 0 2 2 2 1 Sas10/Utp3/C1D family NPV_P10 PF05531.7 EMR67520.1 - 0.2 11.9 1.5 3.9 7.7 0.1 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Nucleo_P87 PF07267.6 EMR67520.1 - 1.5 7.4 8.0 1.9 7.0 5.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Spt5_N PF11942.3 EMR67520.1 - 3.6 8.2 9.4 11 6.6 2.4 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Ras PF00071.17 EMR67521.1 - 7.7e-54 181.4 0.0 8.8e-54 181.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR67521.1 - 8e-18 65.0 0.0 1.1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMR67521.1 - 1.5e-06 27.5 0.0 2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RdRP PF05183.7 EMR67522.1 - 4e-171 570.6 0.1 5.5e-171 570.1 0.1 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF955 PF06114.8 EMR67522.1 - 0.066 12.9 0.3 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF955) ApbA_C PF08546.6 EMR67523.1 - 4.7e-15 55.6 0.0 1.8e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EMR67523.1 - 1.4e-06 27.8 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Herpes_UL79 PF03049.9 EMR67523.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 UL79 family Coq4 PF05019.8 EMR67524.1 - 2.5e-73 245.6 0.0 2.9e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 UBX PF00789.15 EMR67525.1 - 1.4e-07 31.4 0.0 3.2e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 UBX domain TFIIA PF03153.8 EMR67525.1 - 0.0002 21.3 23.3 0.00029 20.8 16.2 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit HNF-1_N PF04814.8 EMR67525.1 - 0.068 13.2 0.3 0.068 13.2 0.2 2.9 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus CDC27 PF09507.5 EMR67525.1 - 2.7 7.0 31.7 4 6.5 22.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PAT1 PF09770.4 EMR67525.1 - 5.5 5.0 31.0 7.7 4.6 21.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Kelch_4 PF13418.1 EMR67526.1 - 0.02 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Galactose oxidase, central domain DUF2076 PF09849.4 EMR67527.1 - 1.3e-09 38.4 13.6 1.5e-09 38.2 9.4 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EMR67527.1 - 0.00079 19.2 5.0 0.0013 18.6 3.5 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EMR67527.1 - 0.0032 17.5 0.8 0.0064 16.5 0.5 1.6 1 1 0 1 1 1 1 GCK domain DUF605 PF04652.11 EMR67527.1 - 0.05 12.9 7.1 0.058 12.7 4.9 1.1 1 0 0 1 1 1 0 Vta1 like SURF1 PF02104.10 EMR67528.1 - 1.6e-63 214.4 0.1 2.2e-63 213.9 0.1 1.2 1 0 0 1 1 1 1 SURF1 family RE_TdeIII PF09520.5 EMR67529.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII Hex_IIIa PF02455.11 EMR67529.1 - 4 6.0 14.9 0.4 9.3 6.4 1.9 1 1 0 2 2 2 0 Hexon-associated protein (IIIa) NmrA PF05368.8 EMR67531.1 - 3.5e-42 144.2 0.2 4.4e-42 143.9 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR67531.1 - 5.7e-07 29.7 0.8 3.5e-06 27.1 0.6 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMR67531.1 - 0.0018 17.0 0.0 0.0027 16.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Melibiase PF02065.13 EMR67532.1 - 4.2e-08 32.2 0.0 2.6e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 Melibiase DUF905 PF06006.7 EMR67532.1 - 0.078 12.3 0.2 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) UCH PF00443.24 EMR67534.1 - 8.7e-21 74.2 0.0 1.1e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMR67534.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DNA_pol_E_B PF04042.11 EMR67535.1 - 1.5e-11 43.9 0.0 1.8e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B COMPASS-Shg1 PF05205.7 EMR67536.1 - 1.2e-24 86.6 0.3 1.2e-24 86.6 0.2 2.7 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 Rep_fac-A_3 PF08661.6 EMR67537.1 - 3.1e-20 72.0 0.0 3.5e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Hydrolase_like PF13242.1 EMR67538.1 - 1.9e-07 30.6 0.0 3.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EMR67538.1 - 7e-07 29.6 0.0 3.6e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR67538.1 - 0.00015 22.2 0.0 0.00034 21.0 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2628 PF10947.3 EMR67539.1 - 0.081 12.7 0.4 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Dak1 PF02733.12 EMR67540.1 - 3.8e-113 377.3 4.7 5.2e-113 376.9 3.2 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EMR67540.1 - 4.2e-44 150.2 0.4 8.1e-44 149.3 0.3 1.5 1 0 0 1 1 1 1 DAK2 domain Antiterm PF03589.8 EMR67540.1 - 0.12 12.4 0.1 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Antitermination protein Prp19_bind PF06991.6 EMR67541.1 - 2.6e-49 167.9 35.6 2.6e-49 167.9 24.7 2.1 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain TPR_12 PF13424.1 EMR67542.1 - 5.4e-17 61.5 7.9 1.1e-07 31.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat NB-ARC PF00931.17 EMR67542.1 - 1.8e-13 50.0 0.0 4.1e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.1 EMR67542.1 - 0.00032 21.2 5.9 1.9 9.2 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EMR67542.1 - 0.001 18.6 7.1 0.012 15.2 0.1 3.4 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 EMR67542.1 - 0.0026 17.5 11.5 4 7.5 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.1 EMR67542.1 - 0.0035 17.4 0.0 0.027 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMR67542.1 - 0.0045 16.9 0.1 0.016 15.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain TPR_10 PF13374.1 EMR67542.1 - 0.011 15.5 10.3 0.076 12.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EMR67542.1 - 0.037 14.3 1.0 25 5.3 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Dehydratase_LU PF02286.10 EMR67542.1 - 0.038 12.2 0.1 0.064 11.5 0.0 1.3 1 0 0 1 1 1 0 Dehydratase large subunit TPR_4 PF07721.9 EMR67542.1 - 0.082 13.3 3.8 4.8 7.9 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EMR67542.1 - 0.13 11.9 5.0 4 7.2 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMR67542.1 - 3.1 8.7 9.3 3.7 8.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Dicty_REP PF05086.7 EMR67543.1 - 0.072 10.8 1.3 0.096 10.4 0.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Scs3p PF10261.4 EMR67543.1 - 0.16 11.0 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Nop14 PF04147.7 EMR67543.1 - 0.52 8.1 4.8 0.74 7.6 3.4 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EMR67543.1 - 2 7.5 8.5 3.1 7.0 5.9 1.2 1 0 0 1 1 1 0 SDA1 DUF3295 PF11702.3 EMR67543.1 - 2.8 6.8 5.7 3.4 6.5 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Daxx PF03344.10 EMR67543.1 - 3.2 6.1 7.0 4.1 5.7 4.9 1.1 1 0 0 1 1 1 0 Daxx Family Zn_clus PF00172.13 EMR67544.1 - 5.4e-09 35.8 11.8 8.4e-09 35.2 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMR67544.1 - 1.8e-06 26.7 0.3 3.4e-06 25.9 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain bZIP_1 PF00170.16 EMR67545.1 - 9.7e-10 38.2 15.5 9.7e-10 38.2 10.7 2.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EMR67545.1 - 3.6e-08 33.1 15.8 3.6e-08 33.1 10.9 2.6 2 1 1 3 3 3 1 Basic region leucine zipper HALZ PF02183.13 EMR67545.1 - 0.0024 17.5 1.5 0.0049 16.5 1.1 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF342 PF03961.8 EMR67545.1 - 0.34 9.2 4.3 0.46 8.8 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 EMR67545.1 - 2.8 8.0 18.2 5.8 6.9 12.6 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 EMR67545.1 - 4.5 6.2 10.7 7.1 5.5 7.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CAF-1_p150 PF11600.3 EMR67545.1 - 6 6.1 25.2 0.05 12.9 10.9 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DivIC PF04977.10 EMR67545.1 - 7.1 6.1 18.6 1 8.8 1.5 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF3675 PF12428.3 EMR67545.1 - 9.2 6.5 7.1 1.8 8.8 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) TPT PF03151.11 EMR67546.1 - 6.3e-21 74.6 16.3 6.3e-21 74.6 11.3 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EMR67546.1 - 0.23 10.3 16.8 0.39 9.5 11.6 1.4 1 0 0 1 1 1 0 UAA transporter family IF-2B PF01008.12 EMR67547.1 - 3.2e-48 164.1 0.0 9e-48 162.6 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Macoilin PF09726.4 EMR67547.1 - 0.92 7.7 4.7 1.4 7.0 3.3 1.2 1 0 0 1 1 1 0 Transmembrane protein PBP PF01161.15 EMR67548.1 - 5.3e-10 39.3 0.0 9.9e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RuBisCO_large_N PF02788.11 EMR67548.1 - 0.4 10.3 2.2 0.7 9.5 1.5 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain DUF2360 PF10152.4 EMR67548.1 - 0.67 10.2 9.0 0.35 11.1 4.6 1.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) TFIIA PF03153.8 EMR67548.1 - 1.2 8.9 4.9 1.6 8.5 3.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LSM PF01423.17 EMR67549.1 - 3e-13 49.0 0.0 4e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain Baculo_44 PF04631.7 EMR67549.1 - 0.086 11.4 0.0 0.099 11.2 0.0 1.1 1 0 0 1 1 1 0 Baculovirus hypothetical protein KAR9 PF08580.5 EMR67550.1 - 4.3 5.4 11.7 4.9 5.2 8.1 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 TALPID3 PF15324.1 EMR67550.1 - 6.5 3.9 12.2 7.7 3.7 8.5 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Alb1 PF09135.6 EMR67551.1 - 3.7e-23 82.2 7.7 3.7e-23 82.2 5.4 1.7 1 1 0 1 1 1 1 Alb1 PRA-PH PF01503.12 EMR67551.1 - 0.5 10.6 2.4 0.42 10.9 0.6 1.7 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Ribosomal_L4 PF00573.17 EMR67552.1 - 6.5e-47 159.4 0.0 8.3e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Scm3 PF10384.4 EMR67552.1 - 0.017 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Centromere protein Scm3 ECH_C PF13766.1 EMR67553.1 - 8.9e-38 129.0 0.0 2.1e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EMR67553.1 - 6.6e-27 94.1 0.1 6.4e-26 90.9 0.0 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SPRY PF00622.23 EMR67554.1 - 2e-20 73.0 0.0 2.5e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 SPRY domain SET PF00856.23 EMR67555.1 - 2e-07 31.4 0.8 8.7e-07 29.3 0.0 2.3 3 0 0 3 3 3 1 SET domain TPR_12 PF13424.1 EMR67555.1 - 0.00052 19.9 0.4 0.0011 18.8 0.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMR67555.1 - 0.21 11.6 1.1 2.7 8.1 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMR67555.1 - 0.42 10.5 1.8 0.82 9.6 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Condensation PF00668.15 EMR67556.1 - 1.4e-07 30.6 0.0 1.9e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Condensation domain HxxPF_rpt PF13745.1 EMR67556.1 - 2.1e-07 31.1 0.1 5.5e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain Ribophorin_I PF04597.9 EMR67558.1 - 1.1e-125 419.6 0.8 1.2e-125 419.4 0.6 1.0 1 0 0 1 1 1 1 Ribophorin I Hexokinase_2 PF03727.11 EMR67559.1 - 5.3e-90 300.8 0.0 7.4e-90 300.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EMR67559.1 - 2.2e-77 259.0 0.0 1.5e-76 256.3 0.0 1.9 2 0 0 2 2 2 1 Hexokinase RNA_pol_I_A49 PF06870.7 EMR67560.1 - 0.29 9.6 1.4 0.41 9.1 1.0 1.1 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor Complex1_49kDa PF00346.14 EMR67561.1 - 3.2e-131 436.3 0.0 4.1e-131 435.9 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Maff2 PF12750.2 EMR67561.1 - 0.13 11.8 0.0 0.33 10.4 0.0 1.7 1 0 0 1 1 1 0 Maff2 family SSF PF00474.12 EMR67562.1 - 4.5e-09 35.4 17.0 6.5e-09 34.9 11.8 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3325 PF11804.3 EMR67562.1 - 0.017 15.0 10.6 0.017 15.0 7.4 3.8 3 2 1 4 4 4 0 Protein of unknown function (DUF3325) ARL6IP6 PF15062.1 EMR67562.1 - 0.068 13.0 1.4 0.64 9.9 0.0 2.5 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Methyltransf_30 PF05430.6 EMR67562.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase adh_short PF00106.20 EMR67564.1 - 2.7e-29 102.2 1.3 3.4e-29 101.9 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR67564.1 - 7.2e-24 84.8 0.0 9.6e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR67564.1 - 7.8e-16 58.2 0.5 1.1e-15 57.8 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR67564.1 - 0.036 13.4 0.2 0.053 12.9 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR67564.1 - 0.037 14.0 1.0 0.055 13.4 0.7 1.5 1 1 0 1 1 1 0 NADH(P)-binding Rho_Binding PF08912.6 EMR67564.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 Rho Binding Osteopontin PF00865.13 EMR67567.1 - 0.023 13.9 2.4 0.039 13.2 1.6 1.3 1 0 0 1 1 1 0 Osteopontin F-box PF00646.28 EMR67568.1 - 9.7e-05 21.9 0.1 0.00028 20.4 0.1 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 EMR67568.1 - 0.001 18.6 0.3 0.89 9.2 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Ubie_methyltran PF01209.13 EMR67568.1 - 0.042 12.9 0.1 0.071 12.2 0.1 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Peptidase_M28 PF04389.12 EMR67569.1 - 1.8e-24 86.4 0.0 3e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EMR67569.1 - 7.7e-07 28.8 0.0 1.7e-05 24.4 0.0 2.1 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 XFP PF03894.10 EMR67569.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Pectate_lyase_3 PF12708.2 EMR67570.1 - 3.8e-59 200.5 16.7 8.8e-51 173.1 3.9 3.9 3 1 0 3 3 3 2 Pectate lyase superfamily protein VTC PF09359.5 EMR67571.1 - 5.4e-100 334.0 0.2 5.4e-100 334.0 0.2 1.6 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EMR67571.1 - 3.8e-27 95.7 5.4 2.4e-13 50.5 0.9 3.1 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EMR67571.1 - 2.8e-12 46.6 1.1 5.3e-12 45.7 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Pil1 PF13805.1 EMR67572.1 - 3.6e-102 341.1 3.5 5.3e-102 340.5 2.4 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 FAD_binding_3 PF01494.14 EMR67572.1 - 3.5e-23 82.2 0.1 1.1e-20 74.0 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EMR67572.1 - 0.00064 18.7 0.5 0.0056 15.6 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EMR67572.1 - 0.0046 16.7 0.0 0.019 14.7 0.0 2.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMR67572.1 - 0.0075 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR67572.1 - 0.038 12.8 0.0 0.072 11.9 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMR67572.1 - 0.064 13.2 0.1 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 EMR67572.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Lin-8 PF03353.10 EMR67573.1 - 7.5 5.7 12.1 17 4.5 8.4 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist AAA PF00004.24 EMR67574.1 - 5.3e-07 29.8 0.1 2.3e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Aspzincin_M35 PF14521.1 EMR67576.1 - 0.055 13.9 0.1 0.12 12.9 0.0 1.6 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase DUF3405 PF11885.3 EMR67577.1 - 8.3e-183 608.1 9.0 1.4e-182 607.3 6.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) LRR19-TM PF15176.1 EMR67578.1 - 0.41 10.3 2.9 0.49 10.1 0.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain AFG1_ATPase PF03969.11 EMR67579.1 - 5.5e-72 242.5 0.0 4.1e-67 226.5 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase LigB PF02900.13 EMR67580.1 - 2.6e-28 98.7 0.1 4.1e-28 98.1 0.1 1.3 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase BBS1 PF14779.1 EMR67580.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 MFS_1 PF07690.11 EMR67581.1 - 2.5e-26 92.2 32.9 3.4e-26 91.8 22.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3775 PF12616.3 EMR67581.1 - 0.038 13.7 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) Abi PF02517.11 EMR67581.1 - 3.7 7.7 10.6 0.18 11.9 0.5 3.4 3 1 0 3 3 3 0 CAAX protease self-immunity Ank_2 PF12796.2 EMR67582.1 - 0.00029 21.1 0.0 0.00068 19.9 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) ketoacyl-synt PF00109.21 EMR67583.1 - 1.3e-45 155.8 0.0 4.4e-36 124.6 0.0 2.2 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMR67583.1 - 6.9e-30 103.3 0.2 1.7e-29 102.0 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Pkinase_Tyr PF07714.12 EMR67586.1 - 0.082 11.9 0.0 4.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Amidase PF01425.16 EMR67587.1 - 6.2e-54 183.5 0.5 2.6e-51 174.8 0.2 2.1 2 0 0 2 2 2 2 Amidase MFS_1 PF07690.11 EMR67588.1 - 1.4e-09 37.1 20.9 2.7e-09 36.2 14.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMR67588.1 - 1.4e-06 27.8 3.1 1.4e-06 27.8 2.1 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EMR67589.1 - 2.4e-14 52.8 29.3 2.4e-13 49.5 7.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 EMR67590.1 - 1.1e-19 71.3 0.0 2.6e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR67590.1 - 2e-12 46.0 0.1 1.1e-11 43.6 0.0 2.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMR67590.1 - 6.9e-11 42.0 0.0 1.1e-09 38.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EMR67590.1 - 1.1e-06 27.8 0.0 1.3e-05 24.3 0.0 2.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMR67590.1 - 2.9e-06 27.3 0.0 5.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR67590.1 - 5.6e-05 22.2 0.1 0.013 14.3 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Mqo PF06039.10 EMR67590.1 - 0.00012 20.4 0.3 0.22 9.6 0.0 2.2 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.1 EMR67590.1 - 0.00017 21.4 0.0 0.19 11.5 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EMR67590.1 - 0.0027 16.8 0.3 0.0063 15.6 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EMR67590.1 - 0.14 12.6 3.1 13 6.2 0.4 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.19 EMR67590.1 - 0.21 11.9 0.5 22 5.3 0.0 3.3 4 0 0 4 4 4 0 Semialdehyde dehydrogenase, NAD binding domain Bac_luciferase PF00296.15 EMR67591.1 - 9e-64 215.5 0.9 1.3e-63 215.0 0.6 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase BNIP3 PF06553.7 EMR67592.1 - 6.9 5.9 7.2 53 3.1 5.4 1.9 1 1 1 2 2 2 0 BNIP3 HTH_25 PF13413.1 EMR67593.1 - 0.13 11.8 0.2 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Bac_luciferase PF00296.15 EMR67594.1 - 1.7e-62 211.2 2.7 2.3e-62 210.9 1.9 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Fe_dep_repress PF01325.14 EMR67594.1 - 0.14 12.0 0.2 0.32 10.9 0.2 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain AAA_23 PF13476.1 EMR67595.1 - 1.8e-12 47.9 36.5 1.8e-12 47.9 25.3 7.6 1 1 2 3 3 3 1 AAA domain SbcCD_C PF13558.1 EMR67595.1 - 7e-12 45.0 0.0 2.4e-11 43.4 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EMR67595.1 - 3.5e-06 26.3 0.0 3.5e-06 26.3 0.0 5.8 3 2 0 4 4 4 1 AAA ATPase domain AAA_21 PF13304.1 EMR67595.1 - 4e-05 23.7 20.0 0.0047 16.9 2.7 4.6 4 1 0 4 4 4 2 AAA domain AAA_13 PF13166.1 EMR67595.1 - 0.0015 17.1 0.1 0.0015 17.1 0.1 7.1 1 1 5 7 7 7 3 AAA domain AAA_29 PF13555.1 EMR67595.1 - 0.0019 17.6 0.1 0.0094 15.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain TMF_TATA_bd PF12325.3 EMR67595.1 - 0.0069 16.1 6.3 0.0069 16.1 4.4 10.0 4 4 6 11 11 11 1 TATA element modulatory factor 1 TATA binding ABC_tran PF00005.22 EMR67595.1 - 0.11 12.8 0.0 0.11 12.8 0.0 7.8 3 2 1 5 5 5 0 ABC transporter AAA_22 PF13401.1 EMR67595.1 - 0.15 12.2 0.1 0.15 12.2 0.0 5.3 6 3 0 6 6 6 0 AAA domain GATA PF00320.22 EMR67598.1 - 6.1e-16 57.4 4.9 1e-15 56.7 3.4 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EMR67598.1 - 3.8e-09 36.5 0.0 6.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EMR67598.1 - 1.3e-08 34.8 0.0 2.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EMR67598.1 - 1.7e-06 27.7 0.1 7.4e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EMR67598.1 - 4e-06 27.1 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 EMR67598.1 - 0.002 18.1 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold DUF2400 PF09674.5 EMR67598.1 - 0.0075 16.0 0.1 0.16 11.6 0.0 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2400) TF_Zn_Ribbon PF08271.7 EMR67598.1 - 0.18 11.1 0.6 1 8.7 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.1 EMR67598.1 - 3.3 7.5 4.9 0.63 9.8 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) HET PF06985.6 EMR67600.1 - 2.5e-27 95.7 0.0 3.6e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF829 PF05705.9 EMR67601.1 - 7e-43 147.0 0.2 8.6e-43 146.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Ish1 PF10281.4 EMR67602.1 - 5.2e-76 250.2 31.5 1.1e-14 54.1 0.1 8.6 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EMR67602.1 - 1.6e-08 33.7 0.0 9.8 5.8 0.0 8.0 9 0 0 9 9 9 1 SAP domain Slx4 PF09494.5 EMR67602.1 - 1e-05 25.2 3.1 16 5.3 0.1 6.6 8 0 0 8 8 8 1 Slx4 endonuclease HeH PF12949.2 EMR67602.1 - 2.5e-05 23.7 0.0 4.4 6.9 0.0 5.1 5 0 0 5 5 5 1 HeH/LEM domain APC2 PF08672.6 EMR67602.1 - 0.0029 17.8 2.4 50 4.2 0.0 5.9 7 0 0 7 7 7 0 Anaphase promoting complex (APC) subunit 2 Thioredoxin_6 PF13848.1 EMR67602.1 - 0.0055 16.5 0.2 1.8 8.3 0.0 3.8 3 2 2 5 5 5 1 Thioredoxin-like domain Phage_CRI PF05144.9 EMR67602.1 - 0.057 12.5 0.2 0.057 12.5 0.2 2.0 2 0 0 2 2 2 0 Phage replication protein CRI LEM PF03020.10 EMR67602.1 - 0.11 11.9 0.0 19 4.7 0.0 4.1 4 0 0 4 4 4 0 LEM domain SAM_2 PF07647.12 EMR67602.1 - 0.15 11.9 1.5 2.2 8.2 0.1 3.3 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) CinA PF02464.12 EMR67603.1 - 1.1e-36 125.6 2.2 2.5e-36 124.4 1.5 1.6 1 1 0 1 1 1 1 Competence-damaged protein UPF0254 PF06787.6 EMR67603.1 - 0.13 11.7 0.2 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) DUF4360 PF14273.1 EMR67605.1 - 7.8e-39 133.2 0.0 9.2e-39 132.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Glyco_hydro_7 PF00840.15 EMR67607.1 - 5.4e-189 628.0 13.7 6.1e-189 627.8 9.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 NAD_binding_8 PF13450.1 EMR67607.1 - 0.061 13.3 0.0 0.27 11.3 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF3764 PF12594.3 EMR67607.1 - 0.082 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) Methyltransf_11 PF08241.7 EMR67608.1 - 2.1e-23 82.6 0.0 3.9e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR67608.1 - 1.1e-19 70.5 0.0 1.4e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR67608.1 - 1.3e-15 57.1 0.0 2e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMR67608.1 - 6.5e-14 52.2 0.0 9.9e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR67608.1 - 1.9e-13 50.4 0.0 2.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR67608.1 - 1.4e-11 44.9 0.0 2.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR67608.1 - 4.8e-09 36.4 0.0 8.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR67608.1 - 8.5e-08 32.2 0.2 1.8e-07 31.1 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR67608.1 - 4.1e-05 23.0 0.0 7.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.11 EMR67608.1 - 4.8e-05 21.9 0.0 6.4e-05 21.4 0.0 1.2 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 EMR67608.1 - 0.00021 20.7 0.0 0.00042 19.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EMR67608.1 - 0.036 13.1 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EMR67608.1 - 0.066 12.5 0.0 0.17 11.2 0.0 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EMR67608.1 - 0.091 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EMR67608.1 - 0.15 11.1 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CheR PF01739.13 EMR67608.1 - 0.16 11.2 0.0 0.63 9.2 0.0 1.7 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain adh_short PF00106.20 EMR67609.1 - 2.8e-19 69.6 0.0 4.5e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR67609.1 - 1.2e-11 44.8 0.0 1.5e-11 44.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR67609.1 - 2.5e-08 33.7 0.0 3.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMR67609.1 - 0.035 13.2 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_4 PF07993.7 EMR67609.1 - 0.051 12.4 0.1 0.27 10.1 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein Hydrophobin_2 PF06766.6 EMR67611.1 - 2e-26 91.4 9.4 2.6e-26 91.0 6.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Recep_L_domain PF01030.19 EMR67612.1 - 0.011 15.6 0.7 0.031 14.2 0.4 1.7 1 1 0 1 1 1 0 Receptor L domain LRR_8 PF13855.1 EMR67612.1 - 0.11 12.2 1.0 0.31 10.8 0.4 2.0 2 1 0 2 2 2 0 Leucine rich repeat Glyco_hydro_35 PF01301.14 EMR67613.1 - 2.8e-80 270.0 0.0 1.7e-79 267.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EMR67613.1 - 2e-07 31.2 0.0 0.00076 19.7 0.0 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.10 EMR67613.1 - 0.00042 19.5 0.0 0.0016 17.6 0.0 1.9 1 1 0 1 1 1 1 Beta-galactosidase ALF PF03752.8 EMR67613.1 - 0.51 10.2 5.9 1.5 8.7 4.1 1.8 1 0 0 1 1 1 0 Short repeats of unknown function Kinesin PF00225.18 EMR67614.1 - 2.3e-55 187.6 0.0 5e-55 186.5 0.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain Jnk-SapK_ap_N PF09744.4 EMR67614.1 - 0.42 10.6 5.8 0.059 13.3 0.7 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 GST_N_3 PF13417.1 EMR67615.1 - 1.9e-08 34.3 0.0 4.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMR67615.1 - 7.1e-08 32.3 0.0 1.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR67615.1 - 1.3e-06 28.2 0.0 2.1e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR67615.1 - 1e-05 25.9 0.0 1.6e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMR67615.1 - 2.1e-05 24.3 0.7 4.5e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMR67615.1 - 8.1e-05 22.7 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SH3_9 PF14604.1 EMR67617.1 - 0.002 17.6 0.0 0.27 10.8 0.0 3.1 3 0 0 3 3 3 1 Variant SH3 domain DUF3805 PF12712.2 EMR67617.1 - 0.074 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3805) zf-C2H2_4 PF13894.1 EMR67617.1 - 0.46 10.9 2.6 2.8 8.4 0.6 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger FAD_binding_4 PF01565.18 EMR67619.1 - 8.6e-26 90.0 7.4 1.5e-23 82.8 4.0 2.8 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.7 EMR67619.1 - 0.00017 21.4 0.1 0.0005 19.9 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_31 PF01055.21 EMR67620.1 - 7.7e-123 410.5 0.7 9.4e-123 410.2 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EMR67620.1 - 9e-07 28.6 0.3 1.1e-05 25.1 0.0 2.7 3 0 0 3 3 3 1 Galactose mutarotase-like Fungal_trans PF04082.13 EMR67621.1 - 0.0014 17.5 0.1 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mannosyl_trans3 PF11051.3 EMR67622.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative NmrA PF05368.8 EMR67623.1 - 1e-13 51.0 0.0 1.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR67623.1 - 4.5e-12 46.3 0.0 7.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR67623.1 - 0.0052 16.2 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 EMR67623.1 - 0.0054 16.9 0.0 0.044 14.0 0.0 2.3 2 1 0 2 2 2 1 Putative NAD(P)-binding Glyco_trans_4_4 PF13579.1 EMR67623.1 - 0.0071 16.5 2.9 0.045 13.8 0.2 2.8 2 2 0 2 2 2 1 Glycosyl transferase 4-like domain Uma2 PF05685.7 EMR67624.1 - 0.015 14.6 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Putative restriction endonuclease Asp PF00026.18 EMR67625.1 - 6.3e-08 32.2 0.1 1e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.5 EMR67625.1 - 5.1e-06 25.6 2.1 1e-05 24.7 1.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 EMR67625.1 - 0.0015 18.0 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 Podoplanin Peptidase_M43 PF05572.8 EMR67627.1 - 5.9e-12 45.4 2.1 1.5e-11 44.1 0.1 2.0 1 1 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EMR67627.1 - 9.7e-05 22.8 0.2 0.00018 22.0 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMR67627.1 - 0.00011 22.2 0.2 0.00016 21.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EMR67627.1 - 0.00077 19.5 0.2 0.001 19.1 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EMR67627.1 - 0.001 18.8 0.4 0.0025 17.5 0.2 1.5 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.1 EMR67627.1 - 0.016 14.7 0.1 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EMR67627.1 - 0.065 12.0 0.1 0.088 11.6 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_S10 PF00450.17 EMR67629.1 - 4.7e-80 269.7 0.0 5.9e-80 269.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EMR67629.1 - 0.0078 16.1 0.0 0.025 14.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 EMR67630.1 - 4.4e-40 137.5 0.0 3.2e-37 128.1 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 PI3_PI4_kinase PF00454.22 EMR67631.1 - 9.5e-43 146.3 0.0 3.7e-42 144.4 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EMR67631.1 - 4.4e-22 78.1 0.0 8.2e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) FMO-like PF00743.14 EMR67632.1 - 2.2e-40 138.3 0.0 2.6e-19 68.8 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMR67632.1 - 1.1e-22 81.1 2.1 1.2e-21 77.6 1.1 2.3 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR67632.1 - 4.1e-12 46.3 0.0 0.00024 21.0 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMR67632.1 - 7.5e-11 41.7 0.1 0.00042 19.5 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 EMR67632.1 - 1.9e-09 36.9 2.6 5.7e-08 32.0 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMR67632.1 - 1e-08 35.0 0.1 4.7e-07 29.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR67632.1 - 1.3e-07 30.8 12.5 5e-06 25.6 3.4 3.8 3 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR67632.1 - 2.1e-07 31.2 7.0 0.00076 19.8 1.3 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR67632.1 - 3.6e-07 30.1 6.4 6.5e-05 22.7 1.6 4.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EMR67632.1 - 2.1e-06 26.9 3.0 0.00033 19.8 0.8 2.2 2 0 0 2 2 2 2 Thi4 family FAD_oxidored PF12831.2 EMR67632.1 - 6.9e-06 25.4 1.4 1e-05 24.8 1.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EMR67632.1 - 0.00043 20.4 1.7 0.59 10.2 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EMR67632.1 - 0.00061 18.7 1.7 0.00061 18.7 1.2 2.1 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 EMR67632.1 - 0.00073 19.1 1.8 0.32 10.5 0.1 2.6 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EMR67632.1 - 0.0011 17.8 3.9 0.005 15.7 1.4 2.3 2 1 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EMR67632.1 - 0.0038 16.9 1.8 0.089 12.4 0.8 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EMR67632.1 - 0.0087 14.5 4.4 0.017 13.5 1.0 2.6 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.14 EMR67632.1 - 0.024 13.7 0.9 0.024 13.7 0.6 2.2 3 0 0 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.1 EMR67632.1 - 0.025 14.8 0.4 12 6.2 0.1 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_2 PF03446.10 EMR67632.1 - 0.042 13.6 0.2 0.18 11.6 0.1 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 EMR67632.1 - 0.083 12.8 8.1 6 6.8 0.0 3.2 2 1 1 3 3 3 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 EMR67632.1 - 0.14 11.2 0.9 4 6.5 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EMR67632.1 - 0.15 11.3 1.3 2.7 7.3 0.3 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Lycopene_cycl PF05834.7 EMR67632.1 - 0.17 10.7 2.1 0.29 10.0 0.4 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein HSP20 PF00011.16 EMR67633.1 - 7.6e-18 64.2 0.4 3.1e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family DUF4139 PF13598.1 EMR67633.1 - 0.028 13.7 0.3 0.077 12.3 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4139) Glyco_hydro_53 PF07745.8 EMR67634.1 - 3.1e-99 331.9 0.2 4e-99 331.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 TMEM154 PF15102.1 EMR67634.1 - 0.0045 16.6 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Herpes_gE PF02480.11 EMR67634.1 - 0.0079 14.5 0.0 0.015 13.5 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 EMR67634.1 - 0.04 12.7 0.0 0.22 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) SKG6 PF08693.5 EMR67634.1 - 0.065 12.5 0.3 0.15 11.3 0.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CcmD PF04995.9 EMR67634.1 - 0.071 12.8 3.8 0.2 11.4 2.6 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Ribosomal_60s PF00428.14 EMR67634.1 - 4.6 7.7 9.2 0.88 10.0 2.1 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein DMRL_synthase PF00885.14 EMR67635.1 - 1.2e-43 148.2 0.0 1.3e-40 138.4 0.0 2.1 1 1 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Polysacc_deac_1 PF01522.16 EMR67636.1 - 4.3e-22 78.0 0.0 7.4e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase RskA PF10099.4 EMR67636.1 - 0.0045 16.7 1.0 0.0089 15.7 0.7 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Polysacc_deac_2 PF04748.8 EMR67636.1 - 0.023 13.7 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Leader_Erm PF08253.6 EMR67637.1 - 0.036 13.5 1.8 0.084 12.3 1.3 1.6 1 0 0 1 1 1 0 Erm Leader peptide DUF3080 PF11279.3 EMR67637.1 - 0.06 12.4 0.1 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) NmrA PF05368.8 EMR67638.1 - 2.2e-15 56.5 0.0 3.5e-15 55.8 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR67638.1 - 1.3e-12 48.0 0.1 2.6e-12 47.1 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR67638.1 - 4.6e-06 26.2 0.5 9.7e-05 21.9 0.1 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR67638.1 - 0.0044 15.7 0.0 0.0083 14.8 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EMR67638.1 - 0.011 15.3 0.1 0.022 14.4 0.1 1.5 1 0 0 1 1 1 0 KR domain F420_oxidored PF03807.12 EMR67638.1 - 0.014 15.8 0.0 0.044 14.2 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EMR67638.1 - 0.019 14.8 0.3 0.041 13.8 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EMR67638.1 - 0.037 12.9 0.1 0.22 10.3 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_1 PF00175.16 EMR67639.1 - 2.1e-26 92.5 0.0 4.5e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EMR67639.1 - 7.6e-08 32.4 0.0 0.0015 18.4 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EMR67639.1 - 9.7e-05 22.4 0.0 0.00027 21.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Glyco_hydro_17 PF00332.13 EMR67640.1 - 0.045 12.7 0.3 0.13 11.2 0.1 1.9 1 1 0 1 1 1 0 Glycosyl hydrolases family 17 HIT PF01230.18 EMR67641.1 - 1.4e-20 73.6 0.0 2.7e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EMR67641.1 - 0.0018 18.5 0.0 1.2 9.4 0.0 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding SSP160 PF06933.6 EMR67641.1 - 0.22 9.4 7.9 0.29 9.0 5.5 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MSP1_C PF07462.6 EMR67641.1 - 0.99 7.7 3.5 1.2 7.4 2.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus 3Beta_HSD PF01073.14 EMR67642.1 - 1.4e-25 89.6 0.0 5.6e-25 87.5 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMR67642.1 - 2.1e-14 53.5 0.0 3.1e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR67642.1 - 2.7e-11 42.8 0.0 7.3e-11 41.4 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EMR67642.1 - 5.3e-09 36.2 0.0 1.3e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR67642.1 - 1.5e-07 31.2 0.0 3.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMR67642.1 - 1.3e-06 27.5 0.0 2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMR67642.1 - 1e-05 25.6 0.0 9e-05 22.5 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding Polyketide_cyc2 PF10604.4 EMR67644.1 - 0.012 15.7 0.5 0.072 13.2 0.1 2.3 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport PQQ PF01011.16 EMR67644.1 - 0.23 11.0 2.4 0.69 9.5 0.6 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Cys_Met_Meta_PP PF01053.15 EMR67645.1 - 1.5e-55 188.1 0.0 2.8e-54 183.8 0.0 2.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EMR67645.1 - 0.038 12.7 0.0 0.068 11.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Cation_efflux PF01545.16 EMR67646.1 - 2.8e-30 105.3 12.3 3.4e-30 105.0 8.5 1.1 1 0 0 1 1 1 1 Cation efflux family Proteasome PF00227.21 EMR67647.1 - 1.3e-30 106.1 0.1 2.7e-30 105.0 0.1 1.5 1 1 0 1 1 1 1 Proteasome subunit Kinesin PF00225.18 EMR67648.1 - 1.2e-75 254.2 1.3 1.4e-74 250.7 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain DUF1643 PF07799.7 EMR67648.1 - 0.092 12.4 1.3 0.59 9.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1643) Torsin PF06309.6 EMR67648.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA PF00004.24 EMR67649.1 - 6.9e-12 45.7 0.0 1.6e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR67649.1 - 6.6e-07 29.5 0.0 2.1e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMR67649.1 - 0.0001 22.1 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMR67649.1 - 0.00016 21.4 0.0 0.00035 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EMR67649.1 - 0.00017 20.7 0.8 0.01 14.9 0.1 2.5 2 0 0 2 2 2 1 Zeta toxin RuvB_N PF05496.7 EMR67649.1 - 0.00022 20.3 0.0 0.00043 19.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EMR67649.1 - 0.00043 20.1 0.1 0.002 18.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EMR67649.1 - 0.00054 18.7 0.0 0.00094 17.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EMR67649.1 - 0.0011 18.7 2.3 0.0017 18.0 0.0 2.6 3 0 0 3 3 2 1 Part of AAA domain AAA_16 PF13191.1 EMR67649.1 - 0.0032 17.4 0.3 0.015 15.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EMR67649.1 - 0.0033 18.2 0.0 0.013 16.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMR67649.1 - 0.016 14.4 0.1 0.061 12.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 EMR67649.1 - 0.016 15.5 0.0 0.044 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EMR67649.1 - 0.026 13.4 0.0 0.053 12.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 EMR67649.1 - 0.03 13.8 0.1 2.6 7.6 0.0 2.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EMR67649.1 - 0.032 13.6 1.0 1.1 8.6 0.2 2.9 2 1 1 3 3 3 0 AAA domain NTPase_1 PF03266.10 EMR67649.1 - 0.039 13.6 0.7 0.27 10.9 0.1 2.5 2 1 0 2 2 2 0 NTPase AAA_28 PF13521.1 EMR67649.1 - 0.073 13.0 0.0 0.23 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Amidoligase_2 PF12224.3 EMR67650.1 - 8e-22 78.0 0.0 5.2e-18 65.5 0.0 2.6 3 0 0 3 3 3 2 Putative amidoligase enzyme DUF3508 PF12018.3 EMR67651.1 - 0.17 10.8 0.1 0.3 10.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) FAM176 PF14851.1 EMR67651.1 - 1.7 8.3 6.8 1.1 8.9 0.8 2.9 3 0 0 3 3 3 0 FAM176 family DUF3246 PF11596.3 EMR67652.1 - 0.089 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) ADH_zinc_N PF00107.21 EMR67654.1 - 1.3e-08 34.4 0.0 2.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR67654.1 - 0.0027 17.4 0.3 0.11 12.3 0.1 3.0 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 EMR67655.1 - 3.9e-41 141.0 0.0 4.6e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EMR67656.1 - 3.3e-36 124.7 46.4 1.8e-35 122.2 32.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR67656.1 - 4e-12 45.4 14.0 4e-12 45.4 9.7 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EMR67656.1 - 9.3e-09 34.0 13.9 1.4e-08 33.4 9.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1707 PF08044.6 EMR67657.1 - 0.076 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Transferase PF02458.10 EMR67658.1 - 1.3e-10 40.3 0.0 2.8e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 Transferase family ketoacyl-synt PF00109.21 EMR67659.1 - 6.7e-42 143.7 0.2 2.3e-41 141.9 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.7 EMR67659.1 - 1.2e-30 106.3 0.0 3.4e-30 104.8 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EMR67659.1 - 6e-19 68.0 0.1 1.5e-18 66.7 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EMR67659.1 - 1.5e-13 51.0 0.0 6.4e-13 49.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR67659.1 - 3.1e-13 49.7 0.6 6.3e-11 42.3 0.2 2.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EMR67659.1 - 1.3e-12 47.7 0.0 1.8e-11 44.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR67659.1 - 3e-11 43.1 0.0 1.2e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Acyl_transf_1 PF00698.16 EMR67659.1 - 3.4e-09 36.4 0.0 7.1e-07 28.8 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain Methyltransf_25 PF13649.1 EMR67659.1 - 2.3e-08 34.3 0.0 1.7e-07 31.4 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR67659.1 - 2.2e-07 31.2 0.0 8.3e-07 29.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EMR67659.1 - 3.6e-06 26.5 0.0 1.6e-05 24.4 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 EMR67659.1 - 6e-06 26.8 0.0 2.9e-05 24.5 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.20 EMR67659.1 - 0.00018 21.4 0.0 0.00065 19.6 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_26 PF13659.1 EMR67659.1 - 0.00074 19.5 0.1 0.0029 17.6 0.1 2.1 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 EMR67659.1 - 0.042 12.7 0.0 0.078 11.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMR67659.1 - 0.12 11.0 0.0 8.3 5.0 0.0 2.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_32 PF13679.1 EMR67659.1 - 0.25 11.0 0.0 0.72 9.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.14 EMR67660.1 - 3.3e-28 98.7 1.2 1.5e-26 93.3 0.8 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR67660.1 - 2.9e-06 26.4 5.4 3.5e-06 26.1 1.9 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR67660.1 - 0.00014 21.8 0.5 0.00046 20.1 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMR67660.1 - 0.0051 17.1 2.2 0.012 15.9 1.4 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR67660.1 - 0.043 13.6 0.7 0.081 12.7 0.5 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EMR67660.1 - 0.051 13.2 0.4 0.088 12.4 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PrsW-protease PF13367.1 EMR67660.1 - 0.096 11.8 0.4 0.38 9.9 0.0 2.1 3 0 0 3 3 3 0 Protease prsW family Trp_halogenase PF04820.9 EMR67660.1 - 0.22 10.1 1.9 15 4.0 1.3 2.1 1 1 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 EMR67660.1 - 0.37 9.2 1.7 0.53 8.7 1.2 1.2 1 0 0 1 1 1 0 HI0933-like protein LIP PF03583.9 EMR67661.1 - 9.6e-66 221.9 0.2 1.3e-65 221.4 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase MFS_1 PF07690.11 EMR67662.1 - 3.2e-12 45.8 25.7 3.2e-12 45.8 17.8 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR67662.1 - 2e-10 39.5 0.8 2e-10 39.5 0.5 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PrgI PF12666.2 EMR67662.1 - 4.5 7.4 7.5 0.38 10.9 1.0 2.5 2 1 1 3 3 3 0 PrgI family protein Pkinase_Tyr PF07714.12 EMR67663.1 - 0.12 11.3 0.0 13 4.7 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase ABC_tran PF00005.22 EMR67664.1 - 7.2e-34 117.0 0.0 1.4e-33 116.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMR67664.1 - 0.00019 21.4 0.1 0.014 15.3 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EMR67664.1 - 0.00023 21.1 0.0 0.00055 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC_membrane PF00664.18 EMR67664.1 - 0.00026 20.5 4.6 0.00026 20.5 3.2 1.7 2 1 0 2 2 2 1 ABC transporter transmembrane region DUF258 PF03193.11 EMR67664.1 - 0.00064 18.9 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EMR67664.1 - 0.0035 16.4 0.0 0.0064 15.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.24 EMR67664.1 - 0.0041 17.3 0.2 0.15 12.2 0.1 2.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR67664.1 - 0.0043 17.1 0.1 0.026 14.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EMR67664.1 - 0.0054 16.2 0.1 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EMR67664.1 - 0.012 15.9 0.1 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMR67664.1 - 0.04 14.7 0.1 0.22 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMR67664.1 - 0.044 13.2 0.2 0.48 9.8 0.1 2.2 1 1 0 2 2 2 0 AAA-like domain Sigma54_activat PF00158.21 EMR67664.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain SMC_N PF02463.14 EMR67664.1 - 0.057 12.6 0.0 1.2 8.2 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EMR67664.1 - 0.077 13.3 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EMR67664.1 - 0.1 12.3 0.1 0.32 10.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EMR67664.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_M24 PF00557.19 EMR67665.1 - 1.2e-27 96.8 1.4 3.7e-23 82.1 0.2 2.1 1 1 1 2 2 2 2 Metallopeptidase family M24 zf-MYND PF01753.13 EMR67665.1 - 0.039 13.8 2.6 0.039 13.8 1.8 1.9 2 0 0 2 2 2 0 MYND finger Isochorismatase PF00857.15 EMR67666.1 - 1e-14 54.8 0.0 1.4e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF867 PF05908.6 EMR67666.1 - 0.0031 16.6 0.0 0.0045 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF867) TrbH PF07283.6 EMR67666.1 - 0.017 14.9 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Conjugal transfer protein TrbH Con-6 PF10346.4 EMR67666.1 - 0.16 11.3 0.4 0.3 10.5 0.3 1.4 1 0 0 1 1 1 0 Conidiation protein 6 adh_short PF00106.20 EMR67667.1 - 1.3e-21 77.1 0.3 1.5e-21 77.0 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR67667.1 - 5.1e-16 59.1 0.0 6.2e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR67667.1 - 0.00039 20.1 0.1 0.00058 19.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR67667.1 - 0.00044 19.7 0.1 0.00064 19.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EMR67667.1 - 0.004 16.3 0.0 0.17 11.0 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EMR67667.1 - 0.0097 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR67667.1 - 0.025 13.8 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family PAE PF03283.8 EMR67667.1 - 0.072 11.7 0.0 0.098 11.2 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Peptidase_M24 PF00557.19 EMR67668.1 - 9.4e-37 126.6 0.1 1.2e-36 126.2 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF1387 PF07139.6 EMR67668.1 - 0.24 10.9 5.8 0.036 13.6 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) GMC_oxred_N PF00732.14 EMR67669.1 - 1.7e-54 184.9 0.0 5.4e-54 183.3 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR67669.1 - 6.7e-36 123.7 0.0 1.2e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMR67669.1 - 1.4e-05 24.2 0.0 0.0023 16.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR67669.1 - 1.6e-05 24.8 0.2 0.00016 21.6 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR67669.1 - 3.1e-05 23.9 0.1 0.019 14.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR67669.1 - 0.00015 20.7 0.1 0.012 14.4 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EMR67669.1 - 0.00023 21.2 0.0 0.97 9.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR67669.1 - 0.00072 18.5 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EMR67669.1 - 0.0022 16.5 0.1 0.061 11.7 0.0 2.6 3 0 0 3 3 3 1 HI0933-like protein tRNA-Thr_ED PF08915.6 EMR67669.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase GIDA PF01134.17 EMR67669.1 - 0.031 13.1 0.0 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 EMR67669.1 - 0.09 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EMR67669.1 - 0.12 10.9 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase RTA1 PF04479.8 EMR67670.1 - 2e-54 184.4 11.6 3e-54 183.8 8.0 1.2 1 0 0 1 1 1 1 RTA1 like protein Kei1 PF08552.6 EMR67670.1 - 0.0034 17.0 0.2 0.0087 15.7 0.1 1.7 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Glyco_hydro_3 PF00933.16 EMR67673.1 - 5.6e-57 193.0 0.0 6.2e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_transf_28 PF03033.15 EMR67674.1 - 8.2e-13 48.3 0.0 2.1e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EMR67674.1 - 9.1e-05 21.1 0.0 0.00013 20.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EMR67674.1 - 0.00092 18.9 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain HCV_capsid PF01543.12 EMR67674.1 - 0.0057 16.6 0.7 0.013 15.4 0.5 1.6 1 0 0 1 1 1 1 Hepatitis C virus capsid protein DUF3824 PF12868.2 EMR67674.1 - 0.023 15.6 6.3 0.039 14.8 4.3 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Cas_Csy4 PF09618.5 EMR67674.1 - 0.09 12.5 3.0 0.14 11.9 2.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) DUF2217 PF10265.4 EMR67674.1 - 0.61 8.7 1.7 0.96 8.1 1.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) MFS_1 PF07690.11 EMR67675.1 - 2.1e-09 36.5 8.6 7e-07 28.2 6.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Kinetochor_Ybp2 PF08568.5 EMR67677.1 - 2.7e-88 296.8 0.0 3.3e-88 296.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin ATP_synt_I PF03899.10 EMR67677.1 - 0.093 12.8 0.5 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 ATP synthase I chain R3H PF01424.17 EMR67678.1 - 4.9e-10 38.9 0.0 9.1e-10 38.0 0.0 1.4 1 0 0 1 1 1 1 R3H domain Abhydrolase_5 PF12695.2 EMR67678.1 - 0.084 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sugar_tr PF00083.19 EMR67679.1 - 1.4e-79 267.7 20.8 1.7e-79 267.5 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR67679.1 - 5.9e-17 61.4 43.8 1e-12 47.5 9.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EMR67679.1 - 0.53 10.3 11.7 3.3 7.8 0.8 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Ank_2 PF12796.2 EMR67680.1 - 8.4e-19 67.7 0.0 3.8e-10 39.9 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMR67680.1 - 1e-14 53.4 0.1 0.052 13.3 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 EMR67680.1 - 4.9e-12 44.8 0.0 0.054 13.7 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 EMR67680.1 - 1.9e-08 34.2 0.0 2.1 8.7 0.0 5.3 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR67680.1 - 5.5e-08 33.1 0.1 2.1 8.9 0.0 5.6 2 2 4 6 6 6 4 Ankyrin repeats (many copies) adh_short PF00106.20 EMR67681.1 - 0.0034 17.3 0.0 0.096 12.5 0.0 2.6 3 0 0 3 3 3 1 short chain dehydrogenase Tyrosinase PF00264.15 EMR67683.1 - 6.8e-37 127.7 0.0 1.1e-36 127.1 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Pec_lyase_C PF00544.14 EMR67684.1 - 1.2e-39 135.9 5.5 1.7e-39 135.4 3.8 1.2 1 0 0 1 1 1 1 Pectate lyase p450 PF00067.17 EMR67685.1 - 1.3e-58 198.6 0.0 1.8e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMR67686.1 - 5.3e-75 252.7 0.0 6.2e-75 252.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IL13 PF03487.8 EMR67687.1 - 0.0082 15.8 0.5 0.12 12.1 0.0 2.6 2 0 0 2 2 2 1 Interleukin-13 Prenyltrans_2 PF13249.1 EMR67687.1 - 0.059 13.7 0.5 0.13 12.6 0.2 1.7 2 0 0 2 2 2 0 Prenyltransferase-like TraV PF09676.5 EMR67687.1 - 0.25 12.0 3.9 0.2 12.3 1.2 1.7 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) DUF2193 PF09959.4 EMR67688.1 - 0.28 9.4 1.8 0.4 8.8 1.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) Peptidase_M43 PF05572.8 EMR67689.1 - 3.2e-13 49.5 0.1 6.3e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EMR67689.1 - 0.00023 21.2 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMR67689.1 - 0.00075 19.4 0.7 0.0014 18.5 0.5 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EMR67689.1 - 0.0014 18.2 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EMR67689.1 - 0.0039 16.9 0.3 0.0075 15.9 0.2 1.4 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EMR67689.1 - 0.0067 15.3 0.1 0.0091 14.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.1 EMR67689.1 - 0.01 16.3 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EMR67689.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase QCR10 PF09796.4 EMR67690.1 - 0.9 9.2 5.0 2.6 7.7 0.1 3.3 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) CBF PF03914.12 EMR67691.1 - 5.9e-47 159.1 0.6 2.2e-46 157.3 0.1 2.3 2 0 0 2 2 2 1 CBF/Mak21 family p450 PF00067.17 EMR67692.1 - 2e-49 168.3 0.0 2.5e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APS_kinase PF01583.15 EMR67693.1 - 3.2e-70 234.8 0.0 4.3e-70 234.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EMR67693.1 - 8.7e-06 25.6 0.0 1.5e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMR67693.1 - 2.2e-05 25.2 0.0 3.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMR67693.1 - 0.00032 21.0 0.0 0.00043 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EMR67693.1 - 0.00089 18.5 0.0 0.0011 18.2 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 EMR67693.1 - 0.032 13.7 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EMR67693.1 - 0.091 12.9 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase FAD_binding_4 PF01565.18 EMR67694.1 - 6.6e-13 48.3 2.2 4e-11 42.5 1.5 2.5 1 1 0 1 1 1 1 FAD binding domain V-ATPase_C PF03223.10 EMR67695.1 - 4.9e-120 400.8 0.2 5.5e-120 400.6 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 EMR67695.1 - 0.033 14.5 0.2 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain AA_permease PF00324.16 EMR67697.1 - 1.7e-46 158.6 42.7 1.2e-42 145.8 24.9 2.0 1 1 1 2 2 2 2 Amino acid permease Chitin_bind_3 PF03067.10 EMR67698.1 - 1e-17 64.9 1.5 1.7e-17 64.2 1.1 1.3 1 0 0 1 1 1 1 Chitin binding domain Serglycin PF04360.7 EMR67698.1 - 0.00028 20.6 1.4 0.00045 19.9 1.0 1.4 1 0 0 1 1 1 1 Serglycin Glypican PF01153.14 EMR67698.1 - 0.07 11.7 0.2 0.099 11.2 0.2 1.1 1 0 0 1 1 1 0 Glypican Mucin PF01456.12 EMR67698.1 - 0.28 10.9 20.2 0.59 9.9 14.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Glyco_hydro_76 PF03663.9 EMR67699.1 - 2e-46 159.0 10.5 8.3e-46 157.0 7.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EMR67699.1 - 9.2e-05 21.6 0.0 0.00026 20.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 EMR67699.1 - 0.0026 17.0 0.0 0.038 13.2 0.0 2.8 3 1 1 4 4 4 1 D-glucuronyl C5-epimerase C-terminus YABBY PF04690.8 EMR67699.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 YABBY protein peroxidase PF00141.18 EMR67701.1 - 2.1e-20 73.2 0.0 2.9e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Abhydrolase_6 PF12697.2 EMR67702.1 - 1.4e-13 51.3 3.7 2.2e-13 50.6 2.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR67702.1 - 1.5e-13 50.7 0.0 2.4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMR67702.1 - 1.4e-07 31.3 0.0 2.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EMR67702.1 - 0.00023 20.7 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMR67702.1 - 0.015 14.5 0.0 0.081 12.1 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family adh_short PF00106.20 EMR67703.1 - 4.1e-30 104.8 4.2 6.1e-30 104.3 2.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR67703.1 - 4.4e-22 79.0 0.7 5.3e-22 78.7 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR67703.1 - 3.5e-14 52.8 1.6 1e-13 51.3 1.1 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMR67703.1 - 6.7e-06 25.1 0.3 5e-05 22.3 0.1 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EMR67703.1 - 5.3e-05 22.7 1.1 0.00012 21.6 0.8 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.1 EMR67704.1 - 1.2e-23 84.2 0.0 2.3e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR67704.1 - 2.6e-16 58.9 0.1 6.2e-14 51.0 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMR67704.1 - 1e-09 37.8 0.1 1.8e-07 30.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EMR67704.1 - 1.7e-09 37.5 0.0 1.7e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMR67704.1 - 1.6e-06 28.0 0.0 0.00021 21.0 0.0 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EMR67704.1 - 0.00029 20.9 0.0 0.0034 17.4 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EMR67704.1 - 0.00071 18.5 0.4 0.005 15.8 0.3 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMR67704.1 - 0.0027 16.6 0.0 0.0053 15.7 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 EMR67704.1 - 0.0033 16.6 0.0 0.006 15.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EMR67704.1 - 0.02 15.1 0.0 0.053 13.8 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Thi4 PF01946.12 EMR67704.1 - 0.037 13.1 0.0 0.48 9.4 0.0 2.6 3 0 0 3 3 3 0 Thi4 family FAD_binding_2 PF00890.19 EMR67704.1 - 0.089 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain KxDL PF10241.4 EMR67705.1 - 5.5e-30 103.1 2.6 7.4e-30 102.6 1.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Mating_C PF12737.2 EMR67705.1 - 5.7e-05 22.1 1.7 0.046 12.6 0.0 2.2 2 0 0 2 2 2 2 C-terminal domain of homeodomain 1 Syntaxin PF00804.20 EMR67705.1 - 0.029 14.5 1.7 0.042 14.0 0.4 1.8 1 1 1 2 2 2 0 Syntaxin XylR_N PF06505.6 EMR67705.1 - 0.032 13.6 0.6 0.15 11.5 0.1 2.1 2 0 0 2 2 2 0 Activator of aromatic catabolism DUF883 PF05957.8 EMR67705.1 - 3.2 8.2 8.4 5.9 7.3 0.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Cir_N PF10197.4 EMR67706.1 - 0.0019 18.1 1.7 0.0019 18.1 1.2 5.8 4 2 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR adh_short PF00106.20 EMR67707.1 - 3.5e-27 95.3 2.9 4.6e-27 94.9 2.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR67707.1 - 4e-27 95.5 0.4 4.7e-27 95.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR67707.1 - 7.9e-11 41.9 1.4 1.2e-10 41.4 1.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EMR67707.1 - 0.0018 17.9 0.1 0.0031 17.1 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain VOMI PF03762.12 EMR67707.1 - 0.065 13.1 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) NAD_binding_10 PF13460.1 EMR67707.1 - 0.19 11.6 3.2 1.5 8.7 2.0 2.4 1 1 1 2 2 2 0 NADH(P)-binding Rick_17kDa_Anti PF05433.10 EMR67708.1 - 0.02 14.5 0.4 0.044 13.4 0.3 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain GMC_oxred_N PF00732.14 EMR67709.1 - 3.4e-56 190.5 0.0 4.2e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EMR67709.1 - 8.1e-08 31.5 0.0 0.00011 21.2 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.19 EMR67709.1 - 8.6e-08 31.4 0.3 0.0077 15.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GMC_oxred_C PF05199.8 EMR67709.1 - 8.7e-08 32.5 0.0 1.5e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EMR67709.1 - 0.00021 21.2 0.0 0.00048 20.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMR67709.1 - 0.00046 19.1 0.4 0.063 12.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 EMR67709.1 - 0.0005 19.0 0.2 0.15 10.8 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EMR67709.1 - 0.00059 19.7 0.1 0.19 11.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR67709.1 - 0.11 12.9 0.3 0.4 11.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR67709.1 - 0.11 12.5 0.1 9 6.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMR67709.1 - 0.15 10.6 0.1 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase CAF-1_p150 PF11600.3 EMR67711.1 - 0.00033 20.1 21.1 0.00033 20.1 14.6 2.7 2 1 1 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal TMPIT PF07851.8 EMR67711.1 - 1.4 7.8 3.1 2.9 6.8 1.7 1.7 2 0 0 2 2 2 0 TMPIT-like protein Pox_Ag35 PF03286.9 EMR67711.1 - 2.6 7.5 28.2 0.58 9.6 1.7 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Borrelia_P83 PF05262.6 EMR67711.1 - 5.4 5.1 20.3 0.12 10.6 6.9 2.2 2 0 0 2 2 2 0 Borrelia P83/100 protein Sporozoite_P67 PF05642.6 EMR67712.1 - 7e-05 20.9 2.4 6.1 4.5 0.0 3.1 2 1 1 3 3 3 1 Sporozoite P67 surface antigen DUF4646 PF15496.1 EMR67712.1 - 0.022 14.8 0.0 6.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) HAP1_N PF04849.8 EMR67712.1 - 0.43 9.4 11.0 0.0097 14.8 2.8 1.6 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Abhydrolase_6 PF12697.2 EMR67713.1 - 4.1e-18 66.1 0.1 5.5e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR67713.1 - 1e-07 31.8 0.2 2e-07 30.8 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMR67713.1 - 0.055 13.3 0.3 0.14 12.0 0.2 1.7 1 1 0 1 1 1 0 Putative lysophospholipase Acetyltransf_1 PF00583.19 EMR67714.1 - 1e-14 54.3 0.1 2.2e-14 53.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMR67714.1 - 2e-06 27.4 0.1 3.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EMR67714.1 - 0.00085 19.4 0.0 0.0016 18.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR67714.1 - 0.0029 17.7 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR67714.1 - 0.006 16.4 0.1 0.014 15.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Cnd2 PF05786.9 EMR67714.1 - 0.12 10.8 2.3 0.17 10.3 1.6 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Fructosamin_kin PF03881.9 EMR67715.1 - 4.7e-24 84.8 0.1 6.1e-24 84.4 0.1 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EMR67715.1 - 0.0017 18.1 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMR67715.1 - 0.0071 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase TPR_12 PF13424.1 EMR67716.1 - 1.2e-16 60.4 8.9 1.1e-09 38.0 0.1 3.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMR67716.1 - 8.6e-11 41.3 3.2 9.3e-07 28.4 1.4 3.9 3 1 0 3 3 3 2 TPR repeat NB-ARC PF00931.17 EMR67716.1 - 2.4e-10 39.7 0.0 2.3e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.12 EMR67716.1 - 1.5e-08 33.9 5.3 0.0062 16.3 0.7 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMR67716.1 - 9.6e-08 31.3 2.7 0.0045 16.5 0.9 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMR67716.1 - 5.6e-05 22.9 3.8 0.22 11.4 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMR67716.1 - 0.00012 21.5 0.1 1 9.3 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMR67716.1 - 0.00061 20.1 2.8 0.15 12.7 0.0 4.3 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMR67716.1 - 0.0057 16.3 1.2 1.4 8.9 0.2 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EMR67716.1 - 0.072 13.2 0.1 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EMR67716.1 - 0.074 13.7 10.8 0.1 13.2 0.1 4.4 4 1 1 5 5 4 0 Tetratricopeptide repeat AAA_22 PF13401.1 EMR67716.1 - 0.081 13.0 0.0 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain TPR_6 PF13174.1 EMR67716.1 - 0.18 12.3 3.3 3.2 8.4 0.2 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat IF-2B PF01008.12 EMR67717.1 - 3.5e-33 114.8 0.2 9.9e-33 113.3 0.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family Alpha_L_fucos PF01120.12 EMR67718.1 - 4.7e-86 288.8 3.5 6.5e-86 288.3 2.5 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.1 EMR67718.1 - 0.0031 17.5 0.4 0.018 15.0 0.0 2.4 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 p450 PF00067.17 EMR67719.1 - 1.5e-37 129.2 0.0 3.8e-23 81.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Pyr_redox_2 PF07992.9 EMR67720.1 - 7.2e-30 104.3 0.2 8.9e-30 104.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR67720.1 - 1.8e-15 57.0 0.1 2e-12 47.3 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR67720.1 - 4.3e-09 36.7 0.1 3e-06 27.4 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR67720.1 - 2.5e-07 29.9 2.7 0.0019 17.1 0.0 3.1 2 1 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 EMR67720.1 - 9.7e-05 21.5 0.4 0.00077 18.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.15 EMR67720.1 - 0.00033 20.7 0.2 0.35 10.9 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EMR67720.1 - 0.00068 18.6 4.2 0.63 8.8 0.1 4.1 4 1 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EMR67720.1 - 0.0009 19.4 0.1 0.3 11.3 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EMR67720.1 - 0.0023 16.8 3.6 0.3 9.8 0.2 3.1 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMR67720.1 - 0.0026 17.7 0.4 0.11 12.5 0.0 2.7 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EMR67720.1 - 0.0099 14.8 0.1 0.11 11.4 0.0 2.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EMR67720.1 - 0.011 14.2 1.0 3.6 5.9 0.2 3.0 2 1 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.9 EMR67720.1 - 0.024 13.2 0.2 0.27 9.8 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase ThiF PF00899.16 EMR67720.1 - 0.083 12.7 0.0 12 5.7 0.0 2.7 3 0 0 3 3 3 0 ThiF family NAD_binding_9 PF13454.1 EMR67720.1 - 0.088 12.5 0.1 8.3 6.1 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pribosyltran PF00156.22 EMR67721.1 - 2.8e-14 52.9 0.0 4.9e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GPCR_chapero_1 PF11904.3 EMR67721.1 - 0.047 12.8 0.0 0.062 12.4 0.0 1.1 1 0 0 1 1 1 0 GPCR-chaperone WD40 PF00400.27 EMR67722.1 - 3.1e-62 204.4 16.8 1.9e-14 52.8 1.3 6.5 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EMR67722.1 - 1.9e-06 26.3 1.9 0.0076 14.4 0.0 3.3 1 1 1 3 3 3 3 Nucleoporin Nup120/160 NLE PF08154.7 EMR67722.1 - 0.029 14.3 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 NLE (NUC135) domain MFS_1_like PF12832.2 EMR67723.1 - 1.8e-14 53.2 2.0 3e-14 52.5 0.0 2.5 3 0 0 3 3 3 1 MFS_1 like family Nucleoplasmin PF03066.10 EMR67723.1 - 0.77 9.2 2.8 1.3 8.5 1.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin PH_6 PF15406.1 EMR67724.1 - 3.4e-44 149.4 2.6 3.4e-44 149.4 1.8 2.5 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 EMR67724.1 - 3.2e-05 24.0 0.0 9.6e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 PH domain ABC_tran PF00005.22 EMR67726.1 - 2e-29 102.6 0.0 3.3e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EMR67726.1 - 1.3e-09 37.6 3.2 8.5e-07 28.4 0.2 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMR67726.1 - 6.3e-06 26.2 0.3 1.1e-05 25.4 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EMR67726.1 - 2.5e-05 24.3 0.6 0.014 15.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EMR67726.1 - 0.00051 19.5 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EMR67726.1 - 0.00054 20.1 2.1 0.0053 16.8 1.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMR67726.1 - 0.0011 18.7 0.1 0.11 12.1 0.1 3.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 EMR67726.1 - 0.0016 18.4 0.2 0.0051 16.7 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EMR67726.1 - 0.0019 17.9 0.2 0.006 16.2 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EMR67726.1 - 0.002 17.9 1.1 0.015 15.0 0.8 2.1 1 1 0 1 1 1 1 Domain of unknown function DUF87 Miro PF08477.8 EMR67726.1 - 0.0025 18.3 0.4 0.019 15.4 0.0 2.4 3 0 0 3 3 3 1 Miro-like protein SbcCD_C PF13558.1 EMR67726.1 - 0.0053 16.6 0.3 0.024 14.5 0.2 2.0 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 EMR67726.1 - 0.012 15.3 0.3 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 NTPase Arch_ATPase PF01637.13 EMR67726.1 - 0.014 15.1 0.0 0.084 12.5 0.0 2.2 2 1 0 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 EMR67726.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EMR67726.1 - 0.021 14.2 1.2 0.17 11.2 0.8 2.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EMR67726.1 - 0.026 14.1 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.1 EMR67726.1 - 0.07 12.7 0.2 0.43 10.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EMR67726.1 - 0.07 12.5 0.2 0.39 10.1 0.1 2.0 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EMR67726.1 - 0.074 12.9 0.4 0.41 10.5 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EMR67726.1 - 0.085 13.6 3.5 1.8 9.4 2.5 2.9 1 1 1 2 2 2 0 AAA domain IIGP PF05049.8 EMR67726.1 - 0.099 11.4 0.0 0.19 10.4 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Hpr_kinase_C PF07475.7 EMR67726.1 - 0.13 11.6 0.4 0.54 9.5 0.0 1.9 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_10 PF12846.2 EMR67726.1 - 0.19 11.1 4.4 0.64 9.3 0.3 2.6 1 1 0 2 2 2 0 AAA-like domain Aminotran_4 PF01063.14 EMR67727.1 - 2.5e-22 79.4 0.0 3.7e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV OPT PF03169.10 EMR67728.1 - 1e-148 496.6 50.9 1.2e-148 496.3 35.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_S10 PF00450.17 EMR67729.1 - 2.7e-93 313.3 0.0 3.5e-93 313.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase 2-Hacid_dh_C PF02826.14 EMR67729.1 - 3.3e-38 130.6 0.0 6.9e-38 129.5 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 EMR67729.1 - 0.0033 17.3 0.1 0.38 10.5 0.0 2.5 2 1 0 2 2 2 2 Alpha/beta hydrolase family Fungal_trans_2 PF11951.3 EMR67730.1 - 2.4e-10 39.5 3.4 6e-10 38.2 2.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.18 EMR67731.1 - 1.7e-08 34.2 5.5 2.2e-08 33.8 3.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region GFO_IDH_MocA PF01408.17 EMR67732.1 - 1.2e-21 77.4 0.1 2.2e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EMR67732.1 - 6.8e-05 23.2 0.1 0.00014 22.1 0.1 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sugar_tr PF00083.19 EMR67733.1 - 9.9e-57 192.4 32.4 1.3e-34 119.5 13.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR67733.1 - 4.3e-11 42.1 32.9 2.5e-08 33.0 4.2 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily T_cell_tran_alt PF15128.1 EMR67733.1 - 0.02 14.2 0.1 0.054 12.9 0.1 1.7 1 0 0 1 1 1 0 T-cell leukemia translocation-altered DUF1228 PF06779.9 EMR67733.1 - 0.18 11.8 0.2 0.18 11.8 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) ADH_zinc_N PF00107.21 EMR67734.1 - 3e-07 30.0 0.0 3.1e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR67734.1 - 1.2e-05 24.9 0.1 5.6e-05 22.8 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain HI0933_like PF03486.9 EMR67734.1 - 0.00061 18.3 0.1 0.0008 17.9 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EMR67734.1 - 0.011 14.6 0.4 0.015 14.1 0.3 1.1 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 EMR67734.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EMR67734.1 - 0.12 12.3 0.3 0.2 11.6 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FtsK_SpoIIIE PF01580.13 EMR67735.1 - 0.00053 19.5 0.0 0.0014 18.1 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 EMR67735.1 - 0.094 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain GFO_IDH_MocA PF01408.17 EMR67736.1 - 3.5e-12 46.9 0.0 6.4e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMR67736.1 - 0.00021 21.0 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F-box-like PF12937.2 EMR67737.1 - 0.00088 18.9 0.0 0.0031 17.1 0.0 2.0 1 0 0 1 1 1 1 F-box-like FTA2 PF13095.1 EMR67738.1 - 1.7e-16 60.4 0.0 6.2e-16 58.6 0.0 1.7 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 adh_short PF00106.20 EMR67739.1 - 1.5e-19 70.5 0.1 2.2e-19 69.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR67739.1 - 1.2e-07 31.5 0.1 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR67739.1 - 5.7e-06 26.2 0.1 6.5e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UbiD PF01977.11 EMR67739.1 - 0.16 10.3 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Glyco_hydro_114 PF03537.8 EMR67740.1 - 9.3e-21 73.3 0.1 1.7e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 ADH_zinc_N PF00107.21 EMR67741.1 - 1.9e-10 40.3 0.0 3.5e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR67741.1 - 1.2e-07 31.4 0.0 2.6e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NB-ARC PF00931.17 EMR67742.1 - 1.2e-07 30.9 0.3 2.3e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.7 EMR67742.1 - 5.9e-07 29.2 0.2 1.4e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EMR67742.1 - 1e-05 25.6 0.0 3.2e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR67742.1 - 4.2e-05 23.6 0.7 0.00017 21.6 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EMR67742.1 - 0.00015 21.5 0.0 0.00041 20.1 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase KAP_NTPase PF07693.9 EMR67742.1 - 0.0017 17.3 0.0 0.078 11.9 0.0 2.4 1 1 1 2 2 2 1 KAP family P-loop domain Sigma54_activ_2 PF14532.1 EMR67742.1 - 0.076 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain But2 PF09792.4 EMR67743.1 - 1.9e-48 163.8 0.6 1.9e-48 163.8 0.4 3.2 3 0 0 3 3 3 1 Ubiquitin 3 binding protein But2 C-terminal domain 2OG-FeII_Oxy_3 PF13640.1 EMR67744.1 - 3.5e-10 40.3 0.0 6.6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EMR67744.1 - 0.00091 18.8 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 EMR67745.1 - 8.7e-18 64.0 0.0 9.9e-17 60.5 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 KR PF08659.5 EMR67746.1 - 1.9e-21 76.5 1.6 1.3e-20 73.8 1.1 2.3 1 1 1 2 2 2 1 KR domain ketoacyl-synt PF00109.21 EMR67746.1 - 5.6e-20 71.8 1.5 4.1e-10 39.5 0.0 3.3 1 1 2 3 3 3 3 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 EMR67746.1 - 1e-13 51.5 0.3 3e-13 50.0 0.2 1.8 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EMR67746.1 - 2e-09 37.0 0.0 5.8e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Ketoacyl-synt_C PF02801.17 EMR67746.1 - 9.3e-06 25.4 0.1 2.5e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EMR67746.1 - 1.7e-05 24.9 0.0 5.8e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Terminase_1 PF03354.10 EMR67746.1 - 0.099 11.0 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 Phage Terminase Glyco_hydro_2 PF00703.16 EMR67749.1 - 4.6e-10 39.9 0.1 2.4e-09 37.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EMR67749.1 - 3.6e-07 29.8 0.0 1.2e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EMR67749.1 - 0.046 12.6 0.1 0.086 11.7 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF2735 PF10931.3 EMR67749.1 - 0.055 13.7 1.6 2.9 8.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2735) Fungal_trans PF04082.13 EMR67751.1 - 5.4e-10 38.5 0.0 6.6e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box PF00646.28 EMR67752.1 - 9.7e-06 25.1 0.7 9.5e-05 21.9 0.0 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EMR67752.1 - 0.0053 16.4 0.7 0.011 15.4 0.1 1.9 2 0 0 2 2 2 1 F-box-like Pam17 PF08566.5 EMR67753.1 - 4.5e-61 205.5 0.0 6e-61 205.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Pex14_N PF04695.8 EMR67753.1 - 0.35 10.9 6.2 0.45 10.5 3.7 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF566 PF04484.7 EMR67753.1 - 6.2 6.2 7.4 8.4 5.7 5.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Transp_cyt_pur PF02133.10 EMR67754.1 - 4.8e-56 190.1 15.1 6.3e-56 189.7 10.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PRRSV_2b PF07069.6 EMR67754.1 - 0.12 12.6 1.1 0.66 10.3 0.0 2.5 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b 2TM PF13239.1 EMR67754.1 - 7.4 6.7 17.0 3.5 7.7 0.4 3.7 4 0 0 4 4 4 0 2TM domain ThiF PF00899.16 EMR67755.1 - 1.7e-38 131.4 0.0 2.6e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EMR67755.1 - 3.6e-22 77.7 0.4 5.1e-18 64.4 0.1 2.4 2 0 0 2 2 2 2 MoeZ/MoeB domain Rhodanese PF00581.15 EMR67755.1 - 1.2e-13 51.4 0.0 2.2e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EMR67755.1 - 0.00066 19.7 0.1 0.0024 17.9 0.0 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MscS_porin PF12795.2 EMR67755.1 - 0.0014 17.9 0.8 0.0022 17.3 0.5 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain NUDE_C PF04880.8 EMR67755.1 - 0.2 12.0 1.1 0.44 10.8 0.7 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region GIDA PF01134.17 EMR67755.1 - 0.82 8.4 2.4 1.1 7.9 1.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lamp PF01299.12 EMR67756.1 - 5.3 6.1 5.9 7.6 5.5 4.1 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) SLX9 PF15341.1 EMR67757.1 - 1.4e-33 115.9 5.9 2.1e-33 115.3 4.1 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Tet_JBP PF12851.2 EMR67759.1 - 0.00026 20.3 0.0 0.00052 19.3 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily adh_short PF00106.20 EMR67760.1 - 1.8e-11 44.2 1.0 1.5e-10 41.2 0.7 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR67760.1 - 1.1e-06 28.4 0.4 1.1e-05 25.2 0.3 2.2 1 1 0 1 1 1 1 KR domain Dak2 PF02734.12 EMR67760.1 - 0.062 12.9 0.2 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 DAK2 domain Tmemb_14 PF03647.8 EMR67760.1 - 0.11 12.8 0.2 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 Transmembrane proteins 14C p450 PF00067.17 EMR67761.1 - 1.5e-38 132.5 0.0 2.3e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EMR67762.1 - 6e-08 32.1 0.2 2.1e-07 30.3 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR67762.1 - 2.3e-05 23.4 3.7 0.0012 17.8 2.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR67762.1 - 0.00017 21.5 1.8 0.00045 20.1 1.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMR67762.1 - 0.00084 18.5 0.2 0.57 9.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EMR67762.1 - 0.0011 18.8 0.1 0.0016 18.3 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR67762.1 - 0.0049 15.7 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EMR67762.1 - 0.014 14.5 0.4 0.023 13.7 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 EMR67762.1 - 0.041 13.9 1.1 0.085 12.9 0.8 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EMR67762.1 - 0.057 13.1 0.1 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 EMR67762.1 - 0.094 13.1 3.1 0.14 12.5 0.7 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EMR67762.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EMR67762.1 - 0.39 9.1 1.4 0.65 8.3 0.9 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EMR67762.1 - 0.86 9.3 2.9 2.1 8.1 1.0 2.2 2 1 0 2 2 2 0 FAD-NAD(P)-binding E1-E2_ATPase PF00122.15 EMR67763.1 - 1e-21 77.0 0.1 3.5e-21 75.3 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EMR67763.1 - 2.3e-15 57.2 0.0 2.5e-14 53.8 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR67763.1 - 2.1e-14 54.4 0.1 3e-10 40.8 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMR67763.1 - 1.7e-11 43.9 0.0 5.8e-11 42.1 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMR67763.1 - 0.00027 20.6 0.0 0.00077 19.1 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMR67763.1 - 0.056 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF3317 PF11779.3 EMR67763.1 - 0.5 9.8 6.8 0.032 13.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) Tannase PF07519.6 EMR67764.1 - 2e-57 194.9 2.4 1.1e-52 179.3 0.1 3.0 1 1 1 2 2 2 2 Tannase and feruloyl esterase GMC_oxred_N PF00732.14 EMR67765.1 - 2.8e-61 207.2 0.0 4.8e-39 134.2 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR67765.1 - 3e-38 131.3 0.0 5.4e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMR67765.1 - 6.8e-05 21.9 0.0 0.0038 16.1 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMR67765.1 - 0.0012 17.8 0.1 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EMR67765.1 - 0.019 14.0 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EMR67765.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR67765.1 - 0.13 11.0 0.1 0.82 8.4 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Cse1 PF08506.5 EMR67765.1 - 0.3 9.6 0.0 0.49 8.9 0.0 1.2 1 0 0 1 1 1 0 Cse1 Pkinase PF00069.20 EMR67766.1 - 2.4e-17 62.9 0.0 2.4e-16 59.6 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR67766.1 - 1.9e-05 23.9 0.0 0.0016 17.5 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Nop10p PF04135.7 EMR67767.1 - 1.4e-18 66.3 0.1 1.7e-18 66.0 0.1 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family 4HBT_3 PF13622.1 EMR67768.1 - 4.9e-41 141.1 8.5 6.2e-41 140.8 5.9 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMR67768.1 - 4.4e-05 23.1 0.0 0.00016 21.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA thioesterase Glyco_transf_25 PF01755.12 EMR67769.1 - 4.1e-06 26.5 0.0 8.2e-06 25.6 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) adh_short PF00106.20 EMR67770.1 - 2.5e-26 92.5 0.2 3.7e-26 92.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR67770.1 - 1.1e-15 58.0 0.0 1.4e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR67770.1 - 4.3e-07 29.7 0.1 6.3e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR67770.1 - 5.5e-05 22.7 0.0 7.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR67770.1 - 7.6e-05 22.7 0.1 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EMR67770.1 - 0.0053 15.9 0.0 0.0068 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.21 EMR67770.1 - 0.027 14.0 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.13 EMR67770.1 - 0.043 13.8 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.14 EMR67771.1 - 2.5e-09 36.6 5.5 1.6e-05 24.1 0.4 2.7 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMR67771.1 - 7.7e-05 22.6 1.1 0.0018 18.2 0.2 3.0 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR67771.1 - 0.00023 20.1 5.1 0.1 11.4 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Ribosomal_S5_C PF03719.10 EMR67771.1 - 0.022 14.0 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain Thi4 PF01946.12 EMR67771.1 - 0.038 13.0 0.3 0.068 12.2 0.2 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EMR67771.1 - 0.039 13.7 1.3 0.97 9.1 0.2 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMR67771.1 - 0.047 13.5 0.2 0.071 12.9 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMR67771.1 - 0.073 11.6 6.1 2.2 6.8 1.2 2.9 2 1 1 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.9 EMR67771.1 - 0.12 10.7 0.4 0.2 10.1 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EMR67771.1 - 0.13 12.6 0.3 0.3 11.5 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RVT_1 PF00078.22 EMR67772.1 - 1.4e-08 34.3 0.0 3.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MerR-DNA-bind PF09278.6 EMR67772.1 - 0.089 13.1 4.0 0.19 12.1 1.1 2.9 3 0 0 3 3 3 0 MerR, DNA binding Lyase_aromatic PF00221.14 EMR67773.1 - 2.7e-140 467.9 8.5 3.8e-140 467.4 5.9 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase NOB1_Zn_bind PF08772.6 EMR67775.1 - 1.3e-30 104.9 0.9 2.2e-30 104.2 0.6 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 EMR67775.1 - 0.007 15.8 1.3 0.007 15.8 0.9 2.5 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain AF1Q PF15017.1 EMR67775.1 - 0.0075 16.1 11.7 0.0075 16.1 8.1 2.2 2 1 0 2 2 2 1 Drug resistance and apoptosis regulator HypA PF01155.14 EMR67775.1 - 0.083 12.5 0.0 0.66 9.6 0.1 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family ADH_N PF08240.7 EMR67776.1 - 2.5e-25 88.3 0.1 3.9e-25 87.7 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR67776.1 - 9.2e-14 51.1 0.0 1.3e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR67776.1 - 0.00091 20.1 0.1 0.0016 19.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EMR67776.1 - 0.016 15.1 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.1 EMR67776.1 - 0.04 13.9 0.1 0.057 13.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.19 EMR67778.1 - 1.5e-60 205.0 34.7 3.6e-40 137.9 15.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR67778.1 - 3.4e-15 55.6 36.5 1.6e-10 40.2 2.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily SNARE_assoc PF09335.6 EMR67778.1 - 0.0024 18.0 0.2 0.0024 18.0 0.1 3.7 2 1 1 3 3 3 1 SNARE associated Golgi protein MFS_1_like PF12832.2 EMR67778.1 - 0.033 13.9 0.1 0.033 13.9 0.1 3.6 2 1 2 4 4 4 0 MFS_1 like family DUF697 PF05128.7 EMR67778.1 - 0.065 12.7 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF697) ADH_N PF08240.7 EMR67779.1 - 4.9e-26 90.6 5.3 1e-25 89.6 3.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR67779.1 - 7e-15 54.7 0.0 1.4e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMR67779.1 - 5.6e-05 22.3 0.3 9.6e-05 21.6 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Apolipoprotein PF01442.13 EMR67780.1 - 0.00043 19.8 0.7 0.00073 19.0 0.5 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Pyr_redox_3 PF13738.1 EMR67782.1 - 4.5e-28 98.6 0.0 3.9e-27 95.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR67782.1 - 2.3e-27 95.4 0.0 7.7e-25 87.0 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EMR67782.1 - 3.2e-16 59.8 0.0 2e-12 47.3 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR67782.1 - 4.1e-15 55.5 0.7 2.8e-11 42.9 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EMR67782.1 - 1.9e-07 30.4 0.4 0.0018 17.3 0.2 3.1 2 1 1 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EMR67782.1 - 5.4e-07 28.9 0.1 0.023 13.8 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EMR67782.1 - 1.2e-06 28.4 1.2 0.26 11.0 0.2 3.7 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 EMR67782.1 - 3.6e-06 27.2 0.1 0.015 15.6 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR67782.1 - 1.2e-05 25.2 0.1 0.0002 21.2 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EMR67782.1 - 1.9e-05 24.6 0.9 0.2 11.6 0.0 3.6 4 0 0 4 4 3 1 TrkA-N domain 3HCDH_N PF02737.13 EMR67782.1 - 5.3e-05 22.9 0.1 0.036 13.7 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EMR67782.1 - 6.7e-05 21.5 0.8 0.035 12.5 0.0 3.6 4 0 0 4 4 4 1 HI0933-like protein GIDA PF01134.17 EMR67782.1 - 7.5e-05 21.7 0.0 1.6 7.5 0.0 3.9 4 0 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EMR67782.1 - 0.00027 21.1 0.0 0.041 14.1 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EMR67782.1 - 0.00028 19.9 0.0 0.039 12.8 0.0 3.2 4 0 0 4 4 4 1 Lycopene cyclase protein Thi4 PF01946.12 EMR67782.1 - 0.00032 19.8 0.0 0.38 9.7 0.0 3.6 4 0 0 4 4 4 1 Thi4 family Shikimate_DH PF01488.15 EMR67782.1 - 0.0004 20.4 0.1 0.43 10.6 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EMR67782.1 - 0.0011 17.8 0.2 0.089 11.6 0.0 3.0 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.16 EMR67782.1 - 0.0029 17.2 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.7 EMR67782.1 - 0.003 16.9 0.1 0.039 13.3 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 EMR67782.1 - 0.0031 16.9 0.1 2 7.8 0.0 2.6 3 0 0 3 3 2 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 EMR67782.1 - 0.0033 16.3 0.2 1.8 7.3 0.0 3.6 4 0 0 4 4 4 1 FAD dependent oxidoreductase SnoaL_2 PF12680.2 EMR67782.1 - 0.0088 16.4 0.0 0.033 14.5 0.0 1.9 2 0 0 2 2 1 1 SnoaL-like domain ThiF PF00899.16 EMR67782.1 - 0.01 15.6 0.1 0.99 9.2 0.0 2.6 2 0 0 2 2 2 0 ThiF family F420_oxidored PF03807.12 EMR67782.1 - 0.011 16.0 0.0 4.7 7.7 0.0 3.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.16 EMR67782.1 - 0.016 14.8 0.3 0.04 13.5 0.2 1.6 2 0 0 2 2 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 EMR67782.1 - 0.043 13.8 0.1 4.9 7.1 0.0 2.7 3 0 0 3 3 2 0 NADH(P)-binding NTF2 PF02136.15 EMR67782.1 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain NAD_binding_2 PF03446.10 EMR67782.1 - 0.13 12.1 0.1 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EMR67782.1 - 0.15 11.7 0.1 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EMR67782.1 - 0.18 11.1 0.1 2 7.7 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain THF_DHG_CYH_C PF02882.14 EMR67782.1 - 0.19 10.7 0.1 7.4 5.6 0.0 2.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fungal_trans PF04082.13 EMR67783.1 - 2.6e-26 92.0 0.0 3.9e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR67783.1 - 5.2e-07 29.4 12.4 8.2e-07 28.8 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2776 PF10951.3 EMR67783.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) WD40 PF00400.27 EMR67784.1 - 9.8e-23 79.1 9.3 2.6e-07 30.2 0.5 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMR67784.1 - 0.053 12.2 0.0 1.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like G-alpha PF00503.15 EMR67785.1 - 5.8e-134 446.6 3.0 7.2e-134 446.3 2.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMR67785.1 - 2.5e-15 56.1 1.7 2.3e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EMR67785.1 - 9.3e-05 21.9 0.0 0.00041 19.8 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EMR67785.1 - 0.0015 19.0 0.6 2.7 8.5 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EMR67785.1 - 0.0056 15.8 2.9 0.27 10.3 0.0 2.6 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EMR67785.1 - 0.0098 15.3 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EMR67785.1 - 0.031 13.7 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.18 EMR67785.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family MMR_HSR1 PF01926.18 EMR67785.1 - 0.11 12.4 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EMR67785.1 - 0.11 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family D123 PF07065.9 EMR67786.1 - 2.3e-79 266.6 0.0 3.8e-79 265.8 0.0 1.4 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 EMR67786.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) TMEM171 PF15471.1 EMR67786.1 - 2.6 6.7 5.0 4.6 5.9 3.5 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF3716 PF12511.3 EMR67787.1 - 3.3e-16 58.6 8.1 5.5e-16 57.9 5.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Med3 PF11593.3 EMR67787.1 - 0.086 12.0 6.3 0.12 11.5 4.3 1.3 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Nnf1 PF03980.9 EMR67788.1 - 1.3e-14 54.0 2.4 2.3e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 Nnf1 SOG2 PF10428.4 EMR67788.1 - 0.38 9.3 11.1 0.49 9.0 7.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.8 EMR67788.1 - 0.86 9.4 14.2 0.93 9.3 9.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Podoplanin PF05808.6 EMR67788.1 - 1.2 8.7 6.8 1.6 8.2 4.7 1.2 1 0 0 1 1 1 0 Podoplanin Suf PF05843.9 EMR67788.1 - 2.4 7.8 6.0 2.7 7.6 4.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RAP1 PF07218.6 EMR67788.1 - 4.8 5.1 7.8 5.8 4.8 5.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAT1 PF09770.4 EMR67788.1 - 7.1 4.7 17.6 7.3 4.6 12.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4203 PF13886.1 EMR67789.1 - 0.14 11.6 4.2 0.2 11.1 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) cwf21 PF08312.7 EMR67790.1 - 4.3e-19 68.0 7.3 1.5e-18 66.3 5.0 2.0 1 0 0 1 1 1 1 cwf21 domain DUF1640 PF07798.6 EMR67791.1 - 0.0018 18.3 10.8 0.0062 16.6 7.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) Apolipoprotein PF01442.13 EMR67791.1 - 0.0096 15.4 6.8 0.012 15.1 4.7 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain FlxA PF14282.1 EMR67791.1 - 0.022 14.7 10.2 0.19 11.6 7.1 2.2 1 1 0 1 1 1 0 FlxA-like protein DUF1191 PF06697.7 EMR67791.1 - 0.04 12.7 0.1 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4635 PF15466.1 EMR67791.1 - 0.054 12.7 1.3 5.6 6.2 0.2 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4635) ALMT PF11744.3 EMR67791.1 - 0.059 12.0 1.3 0.07 11.7 0.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Tnp_P_element PF12017.3 EMR67791.1 - 0.58 9.3 5.0 1 8.5 2.5 1.9 1 1 1 2 2 2 0 Transposase protein Fzo_mitofusin PF04799.8 EMR67791.1 - 3.2 7.0 7.1 8.9 5.6 3.6 2.2 1 1 2 3 3 3 0 fzo-like conserved region adh_short PF00106.20 EMR67792.1 - 9.8e-22 77.6 0.0 1.3e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR67792.1 - 1.7e-10 40.8 0.0 2.7e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR67792.1 - 3.6e-06 26.9 0.0 5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMR67792.1 - 0.00011 22.2 0.8 0.00095 19.2 0.6 2.2 1 1 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EMR67792.1 - 0.00063 19.8 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 EMR67792.1 - 0.00078 19.1 0.3 0.0023 17.6 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 EMR67792.1 - 0.001 19.4 0.0 0.0089 16.4 0.1 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding_2 PF13380.1 EMR67792.1 - 0.0083 16.2 0.2 0.035 14.2 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain THF_DHG_CYH_C PF02882.14 EMR67792.1 - 0.0088 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EMR67792.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 EMR67792.1 - 0.036 14.3 0.0 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Sas10 PF09368.5 EMR67793.1 - 1.9e-22 79.2 9.0 1.9e-22 79.2 6.2 2.6 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EMR67793.1 - 5.7e-12 45.6 1.3 1.6e-11 44.2 0.1 2.5 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Med3 PF11593.3 EMR67793.1 - 0.17 11.1 3.6 0.46 9.6 2.4 1.7 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1771 PF08590.5 EMR67794.1 - 4.2e-23 81.1 9.2 4.2e-23 81.1 6.4 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.16 EMR67794.1 - 2.2e-16 59.8 0.3 2.2e-16 59.8 0.2 2.4 2 1 0 2 2 2 1 Smr domain Zip PF02535.17 EMR67794.1 - 0.44 9.5 5.0 0.61 9.0 3.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter HET PF06985.6 EMR67795.1 - 0.00056 20.0 4.2 0.011 15.9 0.1 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EMR67796.1 - 1.4e-30 106.1 28.4 1.4e-30 106.1 19.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MSA-2c PF12238.3 EMR67797.1 - 5.6 6.5 5.7 7.2 6.2 4.0 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c APH PF01636.18 EMR67798.1 - 1.1e-20 74.4 0.0 1.3e-20 74.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMR67798.1 - 8.1e-06 25.5 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EMR67798.1 - 0.0051 15.9 0.0 0.3 10.1 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.6 EMR67798.1 - 0.15 10.6 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) VanZ PF04892.7 EMR67799.1 - 1.2e-08 34.9 0.7 1.6e-08 34.5 0.5 1.2 1 0 0 1 1 1 1 VanZ like family Nop14 PF04147.7 EMR67799.1 - 0.0035 15.3 18.7 0.0044 15.0 13.0 1.0 1 0 0 1 1 1 1 Nop14-like family DUF4401 PF14351.1 EMR67799.1 - 0.13 11.2 4.2 0.25 10.3 2.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) CENP-T PF15511.1 EMR67799.1 - 0.15 11.2 13.7 0.19 10.9 9.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2457 PF10446.4 EMR67799.1 - 0.32 9.6 20.5 0.44 9.2 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.5 EMR67799.1 - 0.45 9.5 14.6 0.53 9.3 10.1 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.7 EMR67799.1 - 0.81 8.8 13.7 1.1 8.5 9.5 1.2 1 0 0 1 1 1 0 NOA36 protein Vfa1 PF08432.5 EMR67799.1 - 1.2 9.1 7.3 1.6 8.7 5.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2890 PF11081.3 EMR67799.1 - 1.4 8.9 11.1 2.2 8.3 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Tim54 PF11711.3 EMR67799.1 - 1.6 7.2 4.8 2.2 6.7 3.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Paf1 PF03985.8 EMR67799.1 - 1.8 7.2 12.1 3 6.4 8.4 1.3 1 0 0 1 1 1 0 Paf1 Sigma70_ner PF04546.8 EMR67799.1 - 1.8 8.1 13.4 3.1 7.3 9.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 EMR67799.1 - 2.5 6.0 14.8 3.2 5.6 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 EMR67799.1 - 6.1 4.5 10.5 8 4.1 7.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen eIF-3c_N PF05470.7 EMR67799.1 - 9.4 4.1 8.3 12 3.8 5.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus EMP24_GP25L PF01105.19 EMR67800.1 - 0.48 10.1 9.3 0.36 10.5 0.3 3.3 3 1 0 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF4546 PF15079.1 EMR67800.1 - 1.6 7.8 6.5 1 8.4 3.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4546) Fib_alpha PF08702.5 EMR67800.1 - 6.9 6.7 17.9 5.7 7.0 1.5 4.4 3 3 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF310 PF03750.8 EMR67800.1 - 8.5 6.5 7.3 7.7 6.7 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF310) DUF4470 PF14737.1 EMR67801.1 - 1.4e-15 56.8 0.0 3.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 EMR67801.1 - 1.1e-06 28.1 0.3 3.1e-06 26.7 0.1 1.8 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EMR67801.1 - 0.0094 15.8 0.1 0.28 11.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMR67801.1 - 0.04 13.8 0.3 0.098 12.6 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMR67801.1 - 0.13 12.5 0.0 0.44 10.8 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat XPG_I PF00867.13 EMR67802.1 - 1.3e-30 105.3 0.0 1.3e-30 105.3 0.0 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EMR67802.1 - 1.3e-29 102.4 0.0 1.3e-29 102.4 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EMR67802.1 - 3.4e-06 27.2 0.3 4e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF262 PF03235.9 EMR67802.1 - 0.092 12.6 4.0 0.25 11.2 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF262 SRR1 PF07985.7 EMR67803.1 - 0.0025 17.7 0.0 0.0049 16.7 0.0 1.5 1 0 0 1 1 1 1 SRR1 NYN_YacP PF05991.6 EMR67804.1 - 4.5e-05 23.2 0.1 0.00016 21.4 0.0 1.7 2 0 0 2 2 2 1 YacP-like NYN domain DUF2791 PF10923.3 EMR67804.1 - 0.1 11.1 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) adh_short_C2 PF13561.1 EMR67805.1 - 1.4e-27 97.0 0.1 1.6e-27 96.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR67805.1 - 2.8e-27 95.6 1.5 3.4e-27 95.3 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR67805.1 - 7.4e-14 51.8 0.6 9.9e-14 51.3 0.4 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 EMR67805.1 - 0.31 10.5 2.1 0.89 9.1 0.4 2.6 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Acetyltransf_2 PF00797.12 EMR67806.1 - 2e-11 43.9 0.1 1.2e-10 41.3 0.1 2.0 1 1 0 1 1 1 1 N-acetyltransferase Clr5 PF14420.1 EMR67807.1 - 6.5e-13 48.3 0.1 1.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Clr5 domain BH3 PF15285.1 EMR67808.1 - 0.014 14.8 0.1 0.033 13.7 0.1 1.7 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Acyl-CoA_dh_1 PF00441.19 EMR67809.1 - 3.2e-40 137.6 0.5 4.5e-40 137.1 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMR67809.1 - 1.1e-20 72.9 0.2 2e-20 72.0 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EMR67809.1 - 8.1e-19 67.2 0.6 1.5e-18 66.3 0.4 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EMR67809.1 - 1.1e-17 64.5 0.0 2.5e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EMR67809.1 - 1.1e-07 32.1 0.0 2.2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cys_rich_VLP PF14194.1 EMR67809.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich VLP Acetyltransf_1 PF00583.19 EMR67810.1 - 9e-10 38.4 0.0 1.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMR67810.1 - 1.3e-07 31.7 0.3 9.4e-07 28.9 0.1 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR67810.1 - 7.2e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EMR67810.1 - 7.4e-05 22.8 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR67810.1 - 0.0012 18.7 0.0 0.027 14.3 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMR67810.1 - 0.0037 17.1 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EMR67810.1 - 0.012 15.8 0.3 0.073 13.2 0.2 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 EMR67811.1 - 1.3e-29 103.7 5.6 1.7e-29 103.3 3.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR67811.1 - 8.4e-14 51.5 0.4 3e-13 49.7 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR67811.1 - 0.00035 20.2 0.0 0.0008 19.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EMR67811.1 - 0.033 13.7 0.0 0.31 10.5 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein adh_short PF00106.20 EMR67812.1 - 2.9e-17 63.0 0.0 3.9e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR67812.1 - 2.2e-07 30.9 0.0 2.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMR67812.1 - 1.3e-05 25.2 0.1 2.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMR67812.1 - 0.00031 20.4 0.0 0.00075 19.2 0.0 1.6 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EMR67812.1 - 0.00037 20.6 0.0 0.00068 19.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EMR67812.1 - 0.013 14.8 0.0 0.38 10.1 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EMR67812.1 - 0.014 14.3 0.1 0.021 13.8 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ApbA PF02558.11 EMR67812.1 - 0.027 13.8 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Eno-Rase_NADH_b PF12242.3 EMR67812.1 - 0.058 13.1 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_2 PF03446.10 EMR67812.1 - 0.059 13.2 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Thioesterase PF00975.15 EMR67814.1 - 5e-16 59.6 0.0 6.2e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EMR67814.1 - 0.0002 21.2 2.0 0.00054 19.9 1.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR67814.1 - 0.014 15.0 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR67814.1 - 0.033 13.9 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family MARVEL PF01284.18 EMR67815.1 - 0.18 11.5 20.2 0.78 9.5 14.0 1.8 1 1 0 1 1 1 0 Membrane-associating domain Glyco_hydro_43 PF04616.9 EMR67816.1 - 2e-22 79.5 0.0 3.8e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_11 PF00457.12 EMR67817.1 - 1.7e-63 213.2 14.1 1.9e-63 213.1 9.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 ubiquitin PF00240.18 EMR67818.1 - 0.0017 17.7 0.0 0.0044 16.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family NACHT PF05729.7 EMR67820.1 - 0.0034 17.0 0.3 0.0074 15.9 0.2 1.5 1 0 0 1 1 1 1 NACHT domain Glyco_hydro_61 PF03443.9 EMR67821.1 - 1.2e-47 162.5 0.0 1.5e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HAD_2 PF13419.1 EMR67822.1 - 2.1e-22 80.1 0.0 2.9e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR67822.1 - 5.9e-09 35.5 0.0 1.2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EMR67822.1 - 6.6e-08 33.2 0.0 1.6e-07 31.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Methyltransf_23 PF13489.1 EMR67823.1 - 2.6e-11 43.5 0.0 2.9e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR67823.1 - 9.8e-07 29.1 0.0 1.3e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR67823.1 - 5.7e-05 23.5 0.0 8.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR67823.1 - 0.00075 18.6 0.0 0.00098 18.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EMR67823.1 - 0.0017 17.9 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR67823.1 - 0.075 13.6 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMR67823.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pyridoxal_deC PF00282.14 EMR67824.1 - 6.4e-73 245.3 0.0 2.1e-62 210.7 0.0 2.4 3 0 0 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EMR67824.1 - 1.5e-05 23.9 0.0 2.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMR67824.1 - 0.00022 20.4 0.0 0.00028 20.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase ABC_membrane PF00664.18 EMR67825.1 - 2.8e-36 125.3 12.8 3.7e-36 124.9 8.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EMR67825.1 - 3.9e-34 117.8 0.0 1.2e-32 113.1 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EMR67825.1 - 1.1e-06 28.8 0.0 0.0052 16.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 EMR67825.1 - 3e-05 23.3 0.0 0.013 14.7 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMR67825.1 - 4.1e-05 23.6 0.1 0.00059 19.8 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EMR67825.1 - 6.1e-05 23.8 0.0 0.00015 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMR67825.1 - 6.6e-05 22.1 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EMR67825.1 - 0.0005 19.9 0.0 0.003 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMR67825.1 - 0.001 19.2 0.0 0.0052 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EMR67825.1 - 0.0033 16.9 0.0 0.0087 15.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EMR67825.1 - 0.0034 17.3 0.2 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EMR67825.1 - 0.0039 16.6 0.0 0.017 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EMR67825.1 - 0.0079 15.6 0.0 0.021 14.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMR67825.1 - 0.0092 16.2 0.1 0.049 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EMR67825.1 - 0.011 15.7 0.0 0.057 13.3 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 EMR67825.1 - 0.012 15.4 0.6 0.064 13.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EMR67825.1 - 0.017 14.8 0.0 0.052 13.2 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EMR67825.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 EMR67825.1 - 0.039 14.1 0.0 0.24 11.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EMR67825.1 - 0.057 13.9 0.1 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 EMR67825.1 - 0.059 13.0 0.3 0.27 10.8 0.0 2.2 3 0 0 3 3 3 0 NACHT domain AAA_23 PF13476.1 EMR67825.1 - 0.13 12.5 3.5 0.3 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Bromodomain PF00439.20 EMR67826.1 - 1.4e-18 66.5 0.3 1.4e-18 66.5 0.2 2.4 3 0 0 3 3 3 1 Bromodomain Bromo_TP PF07524.8 EMR67826.1 - 1.7e-09 37.2 0.0 4.2e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated FUSC PF04632.7 EMR67826.1 - 9.1 4.5 7.6 21 3.3 5.2 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family 3Beta_HSD PF01073.14 EMR67828.1 - 2.4e-15 56.0 0.0 2.5e-14 52.6 0.0 2.4 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EMR67828.1 - 3.2e-12 46.4 0.0 4.2e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR67828.1 - 3e-06 27.3 0.1 2.5e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMR67828.1 - 3.3e-06 26.1 0.0 0.00036 19.5 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EMR67828.1 - 4e-05 23.5 0.0 0.0001 22.2 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR67828.1 - 9.9e-05 22.0 0.0 0.00024 20.8 0.0 1.6 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMR67828.1 - 0.00063 18.7 0.0 0.00094 18.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EMR67828.1 - 0.0087 14.9 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NOSIC PF08060.8 EMR67828.1 - 0.13 12.0 0.1 0.33 10.7 0.0 1.6 2 0 0 2 2 2 0 NOSIC (NUC001) domain Glyco_hydro_16 PF00722.16 EMR67829.1 - 1.3e-14 53.9 0.1 1.8e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EMR67829.1 - 0.00012 20.4 2.7 0.03 12.4 0.4 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Abhydrolase_6 PF12697.2 EMR67830.1 - 4.4e-13 49.6 1.8 5e-13 49.4 1.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR67830.1 - 6.4e-09 35.7 0.4 7.4e-09 35.5 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2408 PF10303.4 EMR67832.1 - 1.7e-36 125.2 6.3 4.3e-17 62.4 1.8 5.3 2 2 2 4 4 4 3 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.1 EMR67832.1 - 0.001 19.3 4.0 0.14 12.4 0.1 3.9 4 1 0 4 4 4 2 Snapin/Pallidin DUF2984 PF11203.3 EMR67832.1 - 0.18 11.8 1.5 0.74 9.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) YCII PF03795.9 EMR67833.1 - 1.2e-10 41.3 0.0 1.5e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain G-patch PF01585.18 EMR67834.1 - 1.2e-12 47.4 1.0 3.4e-12 45.9 0.7 1.8 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EMR67834.1 - 6.9e-06 25.8 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR67834.1 - 0.0016 18.0 0.0 0.0059 16.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3548 PF12068.3 EMR67834.1 - 0.043 13.0 0.3 0.082 12.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3548) RRM_6 PF14259.1 EMR67834.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Recep_L_domain PF01030.19 EMR67835.1 - 1.9e-12 47.1 0.5 0.021 14.8 0.0 3.7 2 1 1 3 3 3 3 Receptor L domain Ecm33 PF12454.3 EMR67835.1 - 0.027 14.3 3.0 0.027 14.3 2.1 2.2 3 0 0 3 3 3 0 GPI-anchored cell wall organization protein UBX PF00789.15 EMR67836.1 - 0.0022 18.0 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain Pol_alpha_B_N PF08418.5 EMR67836.1 - 0.0035 16.9 7.8 0.0041 16.7 5.4 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Nha1_C PF08619.5 EMR67836.1 - 0.034 13.4 11.9 0.038 13.2 8.2 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus TP53IP5 PF15331.1 EMR67836.1 - 0.3 10.9 8.4 0.4 10.5 5.8 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Selenoprotein_S PF06936.6 EMR67836.1 - 1.1 8.8 15.1 1.6 8.2 10.4 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) Phage_B PF02304.10 EMR67836.1 - 1.4 9.1 8.9 2.3 8.5 6.2 1.3 1 0 0 1 1 1 0 Scaffold protein B AIF-MLS PF14962.1 EMR67836.1 - 1.8 8.1 11.0 2.4 7.7 7.6 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence AF-4 PF05110.8 EMR67836.1 - 4.6 4.9 18.2 5.3 4.7 12.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ribosomal_L18_c PF14204.1 EMR67837.1 - 4e-35 120.2 6.2 5e-35 119.9 4.3 1.1 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 EMR67837.1 - 0.12 12.4 0.6 2 8.5 0.1 2.7 2 1 0 2 2 2 0 Threonine synthase N terminus Ribosomal_L6e PF01159.14 EMR67837.1 - 0.85 9.8 3.4 0.67 10.2 1.4 1.5 1 1 1 2 2 2 0 Ribosomal protein L6e FTCD_C PF04961.7 EMR67837.1 - 2.4 7.5 5.7 1.9 7.8 0.9 2.1 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase DUF3449 PF11931.3 EMR67838.1 - 0.077 12.4 0.5 0.15 11.5 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) TLP-20 PF06088.6 EMR67838.1 - 2.8 7.5 5.3 0.69 9.5 1.3 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PBP1_TM PF14812.1 EMR67838.1 - 9.2 6.6 8.2 7.5 6.9 1.7 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AMP-binding PF00501.23 EMR67839.1 - 2.4e-74 250.2 0.0 7.1e-73 245.3 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMR67839.1 - 8.5e-17 61.8 0.2 2.4e-16 60.4 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_60s PF00428.14 EMR67840.1 - 6.4e-25 87.3 10.0 7.8e-25 87.1 6.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein LEA_6 PF10714.4 EMR67840.1 - 0.068 12.9 3.2 0.1 12.3 2.2 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 AP_endonuc_2 PF01261.19 EMR67841.1 - 8.9e-32 110.0 0.0 1.2e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Aldedh PF00171.17 EMR67842.1 - 2.3e-98 329.5 0.0 2.7e-98 329.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMR67842.1 - 0.014 14.1 0.0 0.034 12.8 0.0 1.6 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) OmdA PF13376.1 EMR67842.1 - 0.66 9.6 3.3 2 8.1 1.7 2.1 1 1 1 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF1510 PF07423.6 EMR67843.1 - 0.019 14.3 2.5 0.028 13.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1469 PF07332.6 EMR67843.1 - 0.031 13.9 0.2 0.031 13.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF3169 PF11368.3 EMR67845.1 - 0.081 12.1 3.5 0.23 10.6 2.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DnaJ PF00226.26 EMR67846.1 - 4e-14 52.1 0.0 9.8e-14 50.8 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF1510 PF07423.6 EMR67846.1 - 0.29 10.4 17.9 0.1 11.9 5.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Trypan_PARP PF05887.6 EMR67846.1 - 0.69 9.7 13.9 0.33 10.7 1.6 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Cu_amine_oxid PF01179.15 EMR67847.1 - 2.2e-119 398.8 6.7 2e-105 352.9 2.0 3.0 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EMR67847.1 - 5.7e-08 32.7 0.1 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Methyltransf_2 PF00891.13 EMR67848.1 - 8.9e-25 87.2 0.0 1.2e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase HTH_24 PF13412.1 EMR67848.1 - 0.003 16.9 0.2 0.0097 15.2 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.5 EMR67848.1 - 0.0033 16.9 0.0 0.0099 15.4 0.0 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_AsnC-type PF13404.1 EMR67848.1 - 0.0041 16.6 0.0 0.012 15.0 0.0 1.8 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.11 EMR67848.1 - 0.013 14.8 0.0 0.031 13.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4_2 PF08281.7 EMR67848.1 - 0.015 14.7 0.1 0.059 12.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 Sigma70_r3 PF04539.11 EMR67848.1 - 0.062 13.1 0.8 0.57 10.1 0.1 2.3 2 0 0 2 2 2 0 Sigma-70 region 3 Glyco_hydro_3 PF00933.16 EMR67849.1 - 4.7e-91 304.8 0.0 6.5e-91 304.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR67849.1 - 3.6e-52 177.1 1.4 1.1e-51 175.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR67849.1 - 3.5e-24 84.5 0.1 6.8e-24 83.5 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Fungal_trans PF04082.13 EMR67850.1 - 5.6e-05 22.1 0.2 7.2e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2474 PF10617.4 EMR67850.1 - 1.8 8.2 6.0 1.4 8.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) NESP55 PF06390.7 EMR67851.1 - 0.003 16.9 10.4 0.003 16.9 7.2 1.8 2 0 0 2 2 2 1 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.6 EMR67851.1 - 0.52 10.1 7.1 0.98 9.2 4.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Kelch_5 PF13854.1 EMR67852.1 - 6.3e-13 48.3 3.3 6.3e-13 48.3 2.3 4.5 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 EMR67852.1 - 0.046 13.2 7.4 0.39 10.2 0.0 3.8 3 0 0 3 3 3 0 Kelch motif Creb_binding PF09030.5 EMR67852.1 - 0.1 12.8 1.5 0.28 11.3 1.0 1.7 1 0 0 1 1 1 0 Creb binding Smr PF01713.16 EMR67853.1 - 5.5e-09 36.0 0.1 1.5e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.5 EMR67853.1 - 0.0045 16.9 3.9 0.0089 16.0 2.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Epimerase PF01370.16 EMR67854.1 - 2e-19 69.9 0.0 3.4e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR67854.1 - 4.5e-11 41.9 0.0 5.9e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMR67854.1 - 6.3e-11 42.6 0.0 3.8e-10 40.0 0.0 2.1 2 1 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EMR67854.1 - 0.0011 18.3 0.0 0.0027 16.9 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family Band_7 PF01145.20 EMR67855.1 - 3.8e-11 43.2 0.2 3.8e-11 43.2 0.1 2.9 3 1 0 3 3 3 1 SPFH domain / Band 7 family Patched PF02460.13 EMR67856.1 - 1.3e-76 258.1 10.5 7.5e-76 255.6 7.3 1.9 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EMR67856.1 - 3.3e-51 172.7 5.7 3.3e-51 172.7 3.9 3.1 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EMR67856.1 - 7.3e-06 24.9 5.9 7.3e-06 24.9 4.1 3.3 4 1 0 4 4 4 1 MMPL family DUF4526 PF15029.1 EMR67856.1 - 0.02 14.4 0.7 0.053 13.0 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) ACR_tran PF00873.14 EMR67856.1 - 4.5 4.5 21.3 0.47 7.7 9.4 2.3 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family DUF1785 PF08699.5 EMR67859.1 - 1.6e-10 40.1 0.5 2.8e-10 39.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Pyridox_oxidase PF01243.15 EMR67860.1 - 8.9e-09 35.2 0.0 1.5e-05 24.8 0.0 2.7 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase DUF1860 PF08949.5 EMR67860.1 - 2 7.9 13.5 0.41 10.2 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1860) CTP_transf_2 PF01467.21 EMR67861.1 - 8e-27 94.2 0.0 1e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Mnd1 PF03962.10 EMR67861.1 - 0.099 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Mnd1 family p450 PF00067.17 EMR67862.1 - 2.5e-26 92.2 0.0 8.8e-20 70.6 0.0 2.9 2 1 1 3 3 3 3 Cytochrome P450 Abhydrolase_6 PF12697.2 EMR67864.1 - 1.1e-14 54.9 6.0 2.2e-14 53.8 3.6 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family LIP PF03583.9 EMR67864.1 - 1.6e-12 47.2 1.1 3.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_5 PF12695.2 EMR67864.1 - 3.1e-12 46.4 0.3 5.7e-12 45.6 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR67864.1 - 1.2e-06 27.9 0.0 0.029 13.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EMR67864.1 - 0.00099 18.7 0.3 0.062 12.8 0.0 2.7 3 0 0 3 3 3 1 alpha/beta hydrolase fold PE-PPE PF08237.6 EMR67864.1 - 0.02 14.3 0.1 0.053 12.9 0.0 1.7 2 0 0 2 2 2 0 PE-PPE domain Thioesterase PF00975.15 EMR67864.1 - 0.034 14.3 0.1 0.063 13.4 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain TauD PF02668.11 EMR67865.1 - 2.9e-49 168.0 0.0 3.4e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Abhydrolase_3 PF07859.8 EMR67866.1 - 1.8e-25 89.7 0.0 5e-25 88.3 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMR67866.1 - 0.032 13.4 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family AXE1 PF05448.7 EMR67866.1 - 0.077 11.4 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EMR67866.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase MFS_1 PF07690.11 EMR67867.1 - 3.9e-29 101.4 27.9 4.6e-29 101.2 19.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_16 PF00722.16 EMR67868.1 - 1.5e-12 47.1 7.3 2.2e-12 46.6 5.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.1 EMR67868.1 - 0.33 11.1 7.3 0.7 10.1 5.1 1.8 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily GMC_oxred_N PF00732.14 EMR67869.1 - 3.3e-59 200.4 0.0 5.5e-59 199.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR67869.1 - 1.1e-32 113.2 0.0 1.8e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EMR67869.1 - 3.8e-06 26.0 0.1 6.7e-06 25.2 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMR67869.1 - 0.0002 21.2 0.1 0.018 14.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR67869.1 - 0.00027 19.9 0.1 0.004 16.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EMR67869.1 - 0.0066 15.3 0.8 0.0099 14.8 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR67869.1 - 0.017 15.1 0.1 0.052 13.5 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EMR67869.1 - 0.029 13.0 0.1 0.046 12.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 EMR67869.1 - 0.039 13.0 0.3 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EMR67869.1 - 0.054 12.5 0.1 0.2 10.6 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EMR67869.1 - 0.12 10.8 0.2 0.22 9.9 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein APG17 PF04108.7 EMR67870.1 - 1.1e-100 337.3 0.1 1.2e-100 337.2 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Hormone_1 PF00103.15 EMR67870.1 - 0.03 13.6 0.2 0.099 11.9 0.1 1.8 1 0 0 1 1 1 0 Somatotropin hormone family Rabaptin PF03528.10 EMR67870.1 - 4.1 7.3 8.6 3.4 7.6 0.3 3.3 3 1 0 3 3 3 0 Rabaptin Flavokinase PF01687.12 EMR67871.1 - 1.2e-13 51.0 0.0 2.3e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Riboflavin kinase Ferric_reduct PF01794.14 EMR67872.1 - 1.1e-15 57.7 10.4 1.1e-15 57.7 7.2 2.0 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EMR67872.1 - 7.7e-11 41.8 0.0 6.2e-10 38.8 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMR67872.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain KR PF08659.5 EMR67873.1 - 3e-26 92.1 0.4 8.1e-26 90.7 0.3 1.7 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 EMR67873.1 - 7.8e-21 73.9 0.1 2.7e-20 72.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMR67873.1 - 6e-20 71.5 0.0 2e-19 69.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EMR67873.1 - 4.6e-18 65.6 0.2 1.3e-17 64.2 0.1 1.8 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EMR67873.1 - 1.1e-14 55.4 0.0 1.8e-13 51.4 0.0 2.8 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 EMR67873.1 - 1.3e-12 48.0 0.0 5e-12 46.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR67873.1 - 1.5e-11 44.4 0.1 4.4e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EMR67873.1 - 1.8e-11 44.0 0.0 5e-11 42.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR67873.1 - 6.8e-11 41.9 0.0 2.3e-10 40.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR67873.1 - 1.3e-09 38.6 0.0 1.4e-08 35.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR67873.1 - 7.2e-08 31.8 0.0 1.8e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EMR67873.1 - 0.0059 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 EMR67873.1 - 0.031 14.2 0.0 0.14 12.1 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain ADH_N PF08240.7 EMR67873.1 - 0.08 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain PCMT PF01135.14 EMR67873.1 - 0.09 12.2 0.0 19 4.7 0.0 2.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 EMR67873.1 - 0.12 11.7 0.2 0.69 9.3 0.0 2.2 2 1 0 2 2 2 0 Putative methyltransferase GST_N_2 PF13409.1 EMR67874.1 - 8.1e-09 35.3 0.0 1.8e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMR67874.1 - 2.3e-07 30.8 0.0 4.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMR67874.1 - 1.9e-06 27.9 0.0 3.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR67874.1 - 0.0016 18.4 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMR67874.1 - 0.0017 18.1 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Abhydrolase_6 PF12697.2 EMR67875.1 - 6.8e-17 62.1 6.1 1.1e-16 61.3 4.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR67875.1 - 6e-11 42.3 0.1 8.8e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR67875.1 - 4.9e-08 32.8 0.2 6.6e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR67875.1 - 0.0051 16.0 0.0 0.0089 15.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EMR67875.1 - 0.045 13.1 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.3 EMR67875.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Cu-oxidase_2 PF07731.9 EMR67876.1 - 7.8e-25 86.9 2.5 9.6e-22 76.9 0.5 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EMR67876.1 - 8.2e-20 70.7 0.0 2.5e-19 69.1 0.0 1.9 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 EMR67876.1 - 9e-05 22.4 0.0 0.00042 20.2 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase adh_short PF00106.20 EMR67878.1 - 1.8e-13 50.7 1.2 8.9e-12 45.2 0.9 2.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR67878.1 - 7.3e-07 29.2 0.1 1.4e-06 28.3 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR67878.1 - 3.1e-05 23.7 1.5 0.0043 16.7 0.0 2.7 2 1 0 2 2 2 2 KR domain Shikimate_DH PF01488.15 EMR67878.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amidase PF01425.16 EMR67879.1 - 4e-73 246.7 0.1 1.6e-72 244.7 0.1 1.8 1 1 0 1 1 1 1 Amidase PHD PF00628.24 EMR67880.1 - 3.1e-10 39.5 5.3 3.1e-10 39.5 3.7 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EMR67880.1 - 0.62 9.4 4.4 1.1 8.5 3.0 1.5 1 0 0 1 1 1 0 PHD-finger UIM PF02809.15 EMR67880.1 - 2.1 8.1 10.1 0.082 12.5 2.0 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif NARP1 PF12569.3 EMR67881.1 - 0.32 9.7 2.6 0.45 9.2 1.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MMR_HSR1 PF01926.18 EMR67882.1 - 8e-11 41.9 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMR67882.1 - 0.0019 18.0 0.1 0.069 12.9 0.0 2.3 1 1 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 EMR67882.1 - 0.021 14.1 0.0 0.059 12.6 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 EMR67882.1 - 0.043 13.8 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EMR67882.1 - 0.047 14.0 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 EMR67882.1 - 0.047 12.5 0.0 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_17 PF13207.1 EMR67882.1 - 0.052 14.3 0.0 0.32 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EMR67882.1 - 0.072 12.5 0.0 2.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.16 EMR67882.1 - 0.074 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF258 PF03193.11 EMR67882.1 - 0.089 11.9 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 E1-E2_ATPase PF00122.15 EMR67884.1 - 1e-66 224.2 3.1 1.2e-66 224.0 0.0 2.6 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EMR67884.1 - 3e-24 86.6 0.0 8e-24 85.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMR67884.1 - 2.5e-13 50.6 0.0 4.5e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMR67884.1 - 1.2e-12 47.1 1.3 2e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMR67884.1 - 0.0013 18.3 0.1 0.0029 17.2 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GNVR PF13807.1 EMR67884.1 - 0.072 12.8 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase DUF3994 PF13159.1 EMR67885.1 - 0.92 9.8 7.5 0.053 13.7 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) RRM_1 PF00076.17 EMR67886.1 - 2.7e-23 81.3 0.0 5.7e-13 48.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR67886.1 - 1.3e-16 60.1 0.0 3.3e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR67886.1 - 1.8e-15 56.6 0.0 5.7e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Yae1_N PF09811.4 EMR67886.1 - 1e-12 47.3 4.2 1e-12 47.3 2.9 2.2 2 0 0 2 2 2 1 Essential protein Yae1, N terminal OB_NTP_bind PF07717.11 EMR67889.1 - 4.2e-29 100.6 0.1 1.3e-28 99.1 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMR67889.1 - 2.2e-28 98.2 0.3 2.2e-28 98.2 0.2 2.2 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMR67889.1 - 2.9e-12 46.2 0.0 7.2e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EMR67889.1 - 6.3e-12 45.4 0.3 1.3e-11 44.4 0.2 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EMR67889.1 - 6.4e-06 25.7 0.2 1.4e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMR67889.1 - 1.6e-05 25.0 0.1 7.3e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EMR67889.1 - 9e-05 21.4 0.0 0.0002 20.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EMR67889.1 - 0.004 16.7 0.0 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMR67889.1 - 0.0049 16.5 0.2 0.016 14.9 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 EMR67889.1 - 0.0069 16.6 0.5 0.14 12.4 0.1 3.0 2 1 1 3 3 3 1 ABC transporter AAA_14 PF13173.1 EMR67889.1 - 0.029 14.2 0.1 0.21 11.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EMR67889.1 - 0.031 13.7 0.0 0.12 11.8 0.0 1.9 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 EMR67889.1 - 0.045 12.6 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.17 EMR67889.1 - 0.045 13.1 0.2 0.13 11.7 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ResIII PF04851.10 EMR67889.1 - 0.061 13.1 0.1 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.11 EMR67889.1 - 0.076 12.2 0.1 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DAP3 PF10236.4 EMR67889.1 - 0.085 11.7 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 KaiC PF06745.8 EMR67889.1 - 0.12 11.4 0.1 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 EMR67889.1 - 0.15 11.6 0.0 0.43 10.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Myosin_head PF00063.16 EMR67889.1 - 0.26 9.2 0.0 0.41 8.6 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) Herpes_ori_bp PF02399.10 EMR67889.1 - 0.27 9.1 0.0 0.39 8.6 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein AAA_23 PF13476.1 EMR67889.1 - 0.51 10.6 0.0 0.51 10.6 0.0 2.5 3 0 0 3 3 1 0 AAA domain Abhydrolase_4 PF08386.5 EMR67890.1 - 6.6e-20 70.9 0.0 8.7e-20 70.5 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein p450 PF00067.17 EMR67891.1 - 1e-15 57.2 0.0 1.1e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 EMR67892.1 - 9.4e-23 81.2 0.0 1.2e-22 80.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR67892.1 - 1.6e-11 44.1 0.0 2.2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EMR67892.1 - 0.0045 16.4 0.0 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Pro_dh PF01619.13 EMR67892.1 - 0.029 13.3 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Proline dehydrogenase Chlorophyllase2 PF12740.2 EMR67892.1 - 0.051 12.4 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EMR67892.1 - 0.064 12.4 0.0 0.16 11.1 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EMR67892.1 - 0.072 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase FAD_binding_3 PF01494.14 EMR67893.1 - 6.3e-06 25.4 0.0 7.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EMR67893.1 - 0.00031 19.6 0.0 0.00045 19.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase CYSTM PF12734.2 EMR67894.1 - 0.0019 18.2 32.8 0.0019 18.2 22.8 6.5 3 3 0 3 3 3 1 Cysteine-rich TM module stress tolerance Pro-rich PF15240.1 EMR67894.1 - 0.059 13.4 53.2 0.073 13.1 36.9 1.1 1 0 0 1 1 1 0 Proline-rich adh_short PF00106.20 EMR67895.1 - 4.8e-09 36.3 3.0 0.00016 21.6 0.1 2.5 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EMR67897.1 - 1.9e-30 105.8 0.1 3.7e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR67897.1 - 4.2e-20 72.3 0.1 9.7e-20 71.1 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.20 EMR67897.1 - 2e-08 34.3 0.0 4.4e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site FSH1 PF03959.8 EMR67898.1 - 3e-28 98.7 0.0 4.5e-28 98.1 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EMR67898.1 - 2.6e-07 30.7 0.2 0.00013 21.9 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR67898.1 - 3.9e-05 23.4 0.0 6.6e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EMR67898.1 - 0.013 14.2 0.0 0.017 13.8 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family Ketoacyl-synt_C PF02801.17 EMR67899.1 - 2.1e-33 114.6 0.0 2.9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EMR67899.1 - 8.3e-09 35.2 0.0 1.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Peroxidase_2 PF01328.12 EMR67900.1 - 3.1e-36 124.6 0.1 3.9e-36 124.3 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 PAH PF02671.16 EMR67901.1 - 2e-50 168.1 0.9 3e-17 61.9 0.5 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EMR67901.1 - 2.4e-37 126.7 0.1 1e-36 124.7 0.0 2.1 2 0 0 2 2 2 1 Sin3 family co-repressor WD40 PF00400.27 EMR67903.1 - 1.2e-27 94.7 4.8 2.6e-08 33.4 0.0 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EMR67903.1 - 3.7e-05 23.5 0.2 0.025 14.2 0.0 2.9 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Fungal_trans_2 PF11951.3 EMR67904.1 - 0.038 12.5 0.0 0.052 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain NAD_binding_10 PF13460.1 EMR67905.1 - 1.2e-08 35.1 0.0 2.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR67905.1 - 0.009 15.2 0.0 0.02 14.1 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Thiolase_N PF00108.18 EMR67906.1 - 4.9e-98 327.3 0.7 4.9e-98 327.3 0.5 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMR67906.1 - 1.5e-46 156.7 1.3 2.6e-46 156.0 0.2 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMR67906.1 - 0.00024 20.6 1.1 0.00024 20.6 0.8 2.4 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EMR67906.1 - 0.2 11.3 5.2 1.1 8.9 0.1 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ret_tiss PF10044.4 EMR67907.1 - 0.00088 19.7 0.7 60 4.2 0.0 6.8 4 3 2 7 7 7 0 Retinal tissue protein CTP_transf_3 PF02348.14 EMR67907.1 - 0.015 14.9 0.1 5.2 6.6 0.0 3.6 2 1 2 4 4 4 0 Cytidylyltransferase DHC_N1 PF08385.7 EMR67907.1 - 0.017 13.5 6.6 4.2 5.6 0.1 5.6 5 1 2 7 7 7 0 Dynein heavy chain, N-terminal region 1 Proteasom_Rpn13 PF04683.8 EMR67907.1 - 0.02 14.9 0.0 7.6 6.7 0.0 4.3 6 0 0 6 6 6 0 Proteasome complex subunit Rpn13 ubiquitin receptor Adaptin_N PF01602.15 EMR67907.1 - 0.033 12.5 0.4 23 3.1 0.0 3.6 2 1 0 3 3 3 0 Adaptin N terminal region Antimicrobial_7 PF08102.6 EMR67907.1 - 0.058 13.4 1.2 34 4.5 0.0 4.0 3 0 0 3 3 3 0 Scorpion antimicrobial peptide DUF3368 PF11848.3 EMR67907.1 - 1.4 8.5 38.0 1.3 8.6 0.0 15.2 18 0 0 18 18 18 0 Domain of unknown function (DUF3368) DUF4423 PF14394.1 EMR67907.1 - 2.7 7.5 3.9 14 5.2 0.0 3.8 5 1 1 6 6 6 0 Domain of unknown function (DUF4423) GMC_oxred_C PF05199.8 EMR67908.1 - 3e-32 111.9 0.1 5e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR67908.1 - 7.3e-24 84.4 0.7 1.8e-14 53.6 0.2 2.9 1 1 0 2 2 2 2 GMC oxidoreductase Epimerase PF01370.16 EMR67909.1 - 1.1e-07 31.4 0.1 4.8e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR67909.1 - 1.8e-05 24.8 0.2 4.3e-05 23.6 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EMR67909.1 - 0.00098 18.1 0.0 0.0062 15.4 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.8 EMR67909.1 - 0.0073 15.5 0.5 0.014 14.6 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.19 EMR67909.1 - 0.019 15.2 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.12 EMR67910.1 - 5e-18 64.9 0.2 1.7e-17 63.2 0.1 1.9 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 EMR67910.1 - 4e-15 56.4 0.0 7.5e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CENP-T PF15511.1 EMR67911.1 - 0.058 12.6 3.0 0.081 12.1 2.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ribosomal_60s PF00428.14 EMR67911.1 - 1.2 9.5 10.5 0.16 12.3 1.7 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein GTP_EFTU PF00009.22 EMR67913.1 - 3.7e-42 143.8 0.0 5.3e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EMR67913.1 - 2.1e-21 75.7 0.0 1.6e-20 72.8 0.0 2.4 1 1 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EMR67913.1 - 7.6e-17 60.9 0.0 1.8e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EMR67913.1 - 1.8e-07 30.9 0.1 7.1e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EMR67913.1 - 3.2e-06 27.1 0.0 7.4e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMR67913.1 - 6.9e-05 22.7 0.1 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMR67913.1 - 0.0057 17.1 0.1 0.018 15.5 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Tox-PL PF15644.1 EMR67913.1 - 0.12 13.0 0.0 0.63 10.8 0.0 2.0 2 0 0 2 2 2 0 Papain fold toxin 1 adh_short_C2 PF13561.1 EMR67914.1 - 9.6e-22 77.9 0.0 1.2e-21 77.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR67914.1 - 6e-11 42.5 0.8 1.5e-10 41.2 0.6 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR67914.1 - 2e-07 30.8 0.1 5e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.8 EMR67914.1 - 0.011 15.2 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Eno-Rase_NADH_b PF12242.3 EMR67914.1 - 0.26 11.1 4.2 3.7 7.3 0.9 2.9 2 1 1 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase His_Phos_1 PF00300.17 EMR67915.1 - 0.00079 19.5 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Rad51 PF08423.6 EMR67915.1 - 0.0019 17.1 0.0 0.0026 16.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 DUF1768 PF08719.6 EMR67916.1 - 2.2e-41 141.2 0.1 8.8e-41 139.2 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) NAD_binding_1 PF00175.16 EMR67917.1 - 2.2e-28 98.9 0.0 7.4e-28 97.2 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMR67917.1 - 2.2e-21 75.7 0.0 4.9e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EMR67917.1 - 2.6e-07 30.6 0.0 0.0011 18.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EMR67917.1 - 0.00036 20.4 0.0 0.00085 19.2 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain AstE_AspA PF04952.9 EMR67918.1 - 1e-29 103.3 0.0 1.4e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family RnfC_N PF13375.1 EMR67918.1 - 0.012 15.2 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Peptidase_M14 PF00246.19 EMR67918.1 - 0.17 11.4 0.0 1.6 8.2 0.0 2.0 1 1 1 2 2 2 0 Zinc carboxypeptidase MnhB PF04039.8 EMR67919.1 - 0.28 11.2 8.5 0.45 10.5 5.9 1.5 1 1 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter MFS_1 PF07690.11 EMR67920.1 - 2.6e-32 111.8 13.8 3.8e-32 111.3 9.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EMR67920.1 - 0.023 14.4 0.3 0.076 12.8 0.2 1.8 1 0 0 1 1 1 0 MFS_1 like family DUF3712 PF12505.3 EMR67922.1 - 7.3e-27 93.8 1.0 1.5e-26 92.8 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Glyco_transf_28 PF03033.15 EMR67923.1 - 1e-23 83.6 0.1 2.9e-23 82.1 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EMR67923.1 - 2.6e-05 22.9 0.0 4.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Pex14_N PF04695.8 EMR67923.1 - 0.093 12.7 0.4 0.18 11.8 0.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ABC_tran PF00005.22 EMR67924.1 - 4.8e-50 169.4 0.0 2.1e-28 99.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMR67924.1 - 1.2e-33 116.7 16.3 3.3e-19 69.3 5.6 2.7 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EMR67924.1 - 1.6e-07 30.7 2.6 0.21 10.7 0.3 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EMR67924.1 - 5.6e-06 26.4 1.3 0.0022 18.0 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EMR67924.1 - 6.1e-06 25.7 0.0 0.011 15.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EMR67924.1 - 5.8e-05 23.5 0.5 0.0046 17.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EMR67924.1 - 9.2e-05 21.4 0.0 0.013 14.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 EMR67924.1 - 0.00012 21.5 2.3 0.062 12.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EMR67924.1 - 0.0013 18.7 0.3 0.15 11.9 0.0 3.7 3 1 0 3 3 3 1 AAA domain DUF258 PF03193.11 EMR67924.1 - 0.0015 17.7 0.2 1.2 8.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EMR67924.1 - 0.0028 18.1 0.4 3.7 8.0 0.0 3.5 3 0 0 3 3 3 1 Miro-like protein AAA_30 PF13604.1 EMR67924.1 - 0.0031 17.0 0.1 2.4 7.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 EMR67924.1 - 0.0054 16.6 0.2 0.29 11.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 EMR67924.1 - 0.013 15.3 0.0 2.5 8.0 0.0 3.3 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 EMR67924.1 - 0.016 15.0 3.4 1.2 8.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_22 PF13401.1 EMR67924.1 - 0.018 15.1 0.0 17 5.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EMR67924.1 - 0.02 14.3 0.1 5.5 6.3 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain Zeta_toxin PF06414.7 EMR67924.1 - 0.022 13.8 0.1 5.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 EMR67924.1 - 0.071 12.5 0.0 6.3 6.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.4 EMR67924.1 - 0.088 11.7 0.1 1.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 EMR67924.1 - 0.13 11.0 0.2 0.28 9.9 0.0 1.6 2 0 0 2 2 2 0 ArgK protein MFS_1 PF07690.11 EMR67926.1 - 1.2e-37 129.4 24.5 1.2e-37 129.4 17.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3149 PF11346.3 EMR67926.1 - 0.016 14.7 1.1 0.016 14.7 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) DUF3671 PF12420.3 EMR67926.1 - 0.049 13.6 6.9 32 4.5 2.5 4.1 3 1 1 4 4 4 0 Protein of unknown function ESSS PF10183.4 EMR67926.1 - 0.18 12.2 0.0 0.18 12.2 0.0 2.5 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Lysis_S PF04971.7 EMR67926.1 - 4 7.1 7.4 21 4.9 0.0 3.8 4 0 0 4 4 4 0 Lysis protein S zf-H2C2_2 PF13465.1 EMR67928.1 - 1.5e-13 50.2 20.7 0.0003 20.9 0.3 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EMR67928.1 - 2.6e-11 43.1 17.9 0.00039 20.5 0.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR67928.1 - 1.1e-09 37.8 15.7 0.00055 20.0 0.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 EMR67928.1 - 0.00072 19.6 8.4 0.052 13.7 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger of C2H2 type GAGA PF09237.6 EMR67928.1 - 0.024 14.2 0.2 0.17 11.4 0.1 2.3 2 0 0 2 2 2 0 GAGA factor zf-C2H2_jaz PF12171.3 EMR67928.1 - 0.073 13.2 6.2 1.4 9.1 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMR67928.1 - 7.2 6.6 8.1 0.8 9.7 0.1 3.0 2 1 0 2 2 2 0 C2H2-type zinc finger Cyclin_N PF00134.18 EMR67929.1 - 7.6e-43 145.1 0.1 5.5e-42 142.3 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMR67929.1 - 6.8e-35 119.5 0.0 1.4e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain TFIIA PF03153.8 EMR67929.1 - 0.36 10.6 9.4 0.48 10.2 6.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L2_C PF03947.13 EMR67931.1 - 6.7e-46 155.2 3.6 7.7e-45 151.8 2.5 2.4 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EMR67931.1 - 3.7e-26 90.8 0.2 8.6e-26 89.7 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TYA PF01021.14 EMR67931.1 - 0.093 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 TYA transposon protein Proteasome PF00227.21 EMR67932.1 - 2.7e-46 157.2 0.0 3.4e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EMR67932.1 - 2.7e-14 52.1 0.3 5.5e-14 51.1 0.2 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal DUF4050 PF13259.1 EMR67933.1 - 0.00064 19.6 0.0 0.00084 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) UPF0547 PF10571.4 EMR67933.1 - 0.78 9.4 0.1 0.78 9.4 0.1 3.0 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 MFS_1 PF07690.11 EMR67935.1 - 9.9e-32 110.0 32.9 9.9e-32 110.0 22.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.27 EMR67936.1 - 0.074 12.9 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 WD domain, G-beta repeat ABA_GPCR PF12430.3 EMR67937.1 - 5.2e-53 179.1 0.6 8.2e-53 178.4 0.0 1.6 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EMR67937.1 - 6.1e-20 71.0 0.0 4.1e-19 68.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) MRP-L46 PF11788.3 EMR67938.1 - 6e-25 88.0 1.1 1.5e-24 86.7 0.0 2.1 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EMR67938.1 - 0.0001 21.9 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PEX11 PF05648.9 EMR67939.1 - 0.0002 20.6 1.9 0.14 11.3 0.0 3.1 3 0 0 3 3 3 3 Peroxisomal biogenesis factor 11 (PEX11) Pyr_redox_2 PF07992.9 EMR67940.1 - 4.1e-27 95.3 0.1 5.7e-17 62.2 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR67940.1 - 1e-13 51.4 0.4 1.1e-11 44.9 0.1 3.3 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR67940.1 - 0.00058 19.9 0.1 1.2 9.0 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EMR67940.1 - 0.076 13.2 0.3 13 6.0 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding Peptidase_M16_C PF05193.16 EMR67941.1 - 8.3e-51 172.2 0.0 1.8e-50 171.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EMR67941.1 - 1.5e-40 138.3 0.0 3.3e-40 137.2 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF2392 PF10288.4 EMR67942.1 - 8.5e-15 55.0 0.0 3.2e-10 40.2 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF2392) Ribosomal_60s PF00428.14 EMR67942.1 - 0.041 14.2 13.6 0.076 13.4 3.6 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.5 EMR67942.1 - 0.2 11.8 2.1 0.62 10.3 1.5 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Abhydrolase_6 PF12697.2 EMR67943.1 - 3.8e-18 66.2 0.0 5.8e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR67943.1 - 1.5e-08 34.5 0.0 0.0024 17.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR67943.1 - 8.6e-05 22.3 0.0 0.00053 19.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMR67943.1 - 0.034 13.4 0.0 2.2 7.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Acetyltransf_1 PF00583.19 EMR67944.1 - 2.3e-08 33.9 0.0 4.3e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMR67944.1 - 2.4e-06 27.6 0.0 6.1e-06 26.3 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR67944.1 - 5.4e-06 26.4 0.0 9.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR67944.1 - 3.9e-05 23.5 0.0 0.0085 15.9 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMR67944.1 - 0.00014 21.6 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EMR67944.1 - 0.0044 16.7 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Mito_carr PF00153.22 EMR67945.1 - 5.9e-60 199.0 1.3 1.6e-20 72.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CorA PF01544.13 EMR67946.1 - 1.4e-08 34.1 1.9 7.6e-08 31.7 0.0 2.8 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein PHF5 PF03660.9 EMR67947.1 - 2.1e-51 172.4 10.6 2.4e-51 172.3 7.4 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EMR67947.1 - 0.83 9.5 15.5 0.16 11.7 5.3 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 EMR67947.1 - 1.4 8.7 15.7 2.9 7.6 0.5 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.24 EMR67947.1 - 5.8 6.6 15.2 0.2 11.3 4.4 2.5 1 1 1 2 2 2 0 PHD-finger Pinin_SDK_memA PF04696.8 EMR67948.1 - 5.1e-24 84.3 11.8 5.1e-24 84.3 8.2 2.1 3 0 0 3 3 3 1 pinin/SDK/memA/ protein conserved region CAF-1_p150 PF11600.3 EMR67949.1 - 0.0065 15.8 12.8 0.01 15.2 8.9 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med3 PF11593.3 EMR67949.1 - 0.024 13.9 5.2 0.033 13.4 3.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CDC27 PF09507.5 EMR67949.1 - 0.063 12.4 9.1 0.096 11.8 6.3 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2461 PF09365.5 EMR67949.1 - 0.12 11.7 0.1 0.12 11.7 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) Spore_coat_CotO PF14153.1 EMR67949.1 - 1.5 8.2 9.8 2.5 7.5 6.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.7 EMR67949.1 - 5.2 6.8 8.7 8.4 6.1 6.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PTCB-BRCT PF12738.2 EMR67950.1 - 8.9e-06 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EMR67950.1 - 0.00026 21.0 0.0 0.00065 19.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Phage_integ_N PF09003.5 EMR67950.1 - 0.015 15.0 0.1 0.042 13.5 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage lambda integrase, N-terminal domain DUF680 PF05079.7 EMR67950.1 - 0.41 11.1 5.6 0.23 11.9 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF680) E1-E2_ATPase PF00122.15 EMR67951.1 - 2.3e-21 75.9 0.2 4.3e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EMR67951.1 - 3.1e-18 66.6 0.1 8.2e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR67951.1 - 2.7e-13 50.8 0.4 4e-12 46.9 0.3 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMR67951.1 - 4e-11 42.7 0.0 1.2e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMR67951.1 - 0.00014 21.5 0.2 0.00037 20.1 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMR67951.1 - 0.0063 16.7 0.1 0.02 15.1 0.1 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase F-box-like PF12937.2 EMR67952.1 - 0.044 13.5 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like CCDC155 PF14662.1 EMR67953.1 - 0.00066 19.3 0.8 0.0011 18.5 0.6 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 DUF2205 PF10224.4 EMR67953.1 - 0.064 12.8 0.5 0.16 11.5 0.3 1.7 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DivIC PF04977.10 EMR67953.1 - 0.074 12.5 1.4 0.19 11.2 1.0 1.6 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.16 EMR67953.1 - 0.14 12.1 0.9 0.35 10.8 0.6 1.7 1 0 0 1 1 1 0 bZIP transcription factor DivIVA PF05103.8 EMR67953.1 - 0.19 11.7 1.2 0.32 11.0 0.8 1.4 1 0 0 1 1 1 0 DivIVA protein HALZ PF02183.13 EMR67953.1 - 0.39 10.4 3.9 0.4 10.4 0.6 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper Mito_fiss_reg PF05308.6 EMR67954.1 - 0.034 13.4 0.4 0.058 12.7 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator MFS_1 PF07690.11 EMR67956.1 - 7.3e-17 61.1 10.3 7.3e-17 61.1 7.1 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily Prefoldin_2 PF01920.15 EMR67957.1 - 2.1e-21 75.6 12.0 2.6e-21 75.3 8.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EMR67957.1 - 0.00069 19.2 9.6 0.0013 18.4 0.3 2.3 2 1 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 EMR67957.1 - 0.0037 17.0 6.5 0.0048 16.6 4.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit Hemagglutinin PF00509.13 EMR67957.1 - 0.0054 14.9 0.2 0.0092 14.1 0.2 1.3 1 0 0 1 1 1 1 Haemagglutinin WEMBL PF05701.6 EMR67957.1 - 0.0092 14.4 8.5 0.01 14.3 5.9 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light COG5 PF10392.4 EMR67957.1 - 0.01 15.8 1.9 2.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 YgaB PF14182.1 EMR67957.1 - 0.011 15.9 2.5 0.011 15.9 1.8 2.2 2 0 0 2 2 2 0 YgaB-like protein NPV_P10 PF05531.7 EMR67957.1 - 0.011 15.9 4.2 0.77 10.0 0.5 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EMR67957.1 - 0.014 15.0 13.3 0.24 10.9 9.2 2.0 1 1 0 1 1 1 0 IncA protein DivIC PF04977.10 EMR67957.1 - 0.029 13.8 17.6 2 7.9 0.9 3.2 2 1 0 2 2 2 0 Septum formation initiator Spc7 PF08317.6 EMR67957.1 - 0.029 13.0 9.0 0.034 12.7 6.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Occludin_ELL PF07303.8 EMR67957.1 - 0.04 14.6 7.1 0.18 12.5 1.4 2.1 2 0 0 2 2 2 0 Occludin homology domain Laminin_II PF06009.7 EMR67957.1 - 0.043 13.5 3.3 2 8.1 0.1 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF4164 PF13747.1 EMR67957.1 - 0.062 13.4 6.8 0.77 9.9 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF1664 PF07889.7 EMR67957.1 - 0.071 12.9 3.1 1.1 9.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.2 EMR67957.1 - 0.073 12.9 12.1 0.66 9.8 0.8 2.1 2 0 0 2 2 2 0 Tropomyosin like FliD_C PF07195.7 EMR67957.1 - 0.079 12.2 5.0 0.19 11.0 3.5 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Sas10_Utp3 PF04000.10 EMR67957.1 - 0.094 12.9 0.7 3.2 8.0 0.3 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Mnd1 PF03962.10 EMR67957.1 - 0.12 11.9 13.0 0.81 9.3 1.1 2.0 1 1 1 2 2 2 0 Mnd1 family DUF4201 PF13870.1 EMR67957.1 - 0.17 11.3 8.2 0.85 9.0 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TBPIP PF07106.8 EMR67957.1 - 0.18 11.3 9.1 1.8 8.1 0.4 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HalX PF08663.5 EMR67957.1 - 0.19 11.7 2.5 15 5.6 0.0 2.3 2 1 0 2 2 2 0 HalX domain DUF4510 PF14971.1 EMR67957.1 - 0.19 11.8 4.1 2.5 8.2 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) DUF3584 PF12128.3 EMR67957.1 - 0.24 8.6 7.8 0.3 8.3 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MscS_porin PF12795.2 EMR67957.1 - 0.26 10.5 12.1 0.64 9.2 0.5 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain CDC37_N PF03234.9 EMR67957.1 - 0.26 11.5 7.0 0.32 11.2 4.9 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding RmuC PF02646.11 EMR67957.1 - 0.28 9.9 8.2 0.47 9.2 1.1 2.0 1 1 1 2 2 2 0 RmuC family Tektin PF03148.9 EMR67957.1 - 0.4 9.1 10.8 0.55 8.7 1.1 2.0 2 0 0 2 2 2 0 Tektin family DUF677 PF05055.7 EMR67957.1 - 0.41 9.2 5.5 0.73 8.4 3.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF677) BRE1 PF08647.6 EMR67957.1 - 0.43 10.5 7.2 1.4 8.9 0.2 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase MutS_IV PF05190.13 EMR67957.1 - 0.49 10.6 5.3 8.5 6.6 0.6 2.2 2 0 0 2 2 2 0 MutS family domain IV DUF4140 PF13600.1 EMR67957.1 - 0.49 10.8 8.8 4.5 7.7 1.8 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FliJ PF02050.11 EMR67957.1 - 0.52 10.3 13.6 0.7 9.9 0.6 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein COG2 PF06148.6 EMR67957.1 - 0.54 10.1 7.9 2.7 7.8 0.2 2.1 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF607 PF04678.8 EMR67957.1 - 0.62 9.9 4.6 0.49 10.3 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Uds1 PF15456.1 EMR67957.1 - 0.62 10.0 5.5 1 9.3 3.8 1.4 1 1 0 1 1 1 0 Up-regulated During Septation Syntaxin-6_N PF09177.6 EMR67957.1 - 0.77 10.2 7.2 3.5 8.0 1.0 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal SlyX PF04102.7 EMR67957.1 - 0.83 10.0 6.0 5.9 7.3 0.0 2.4 2 1 0 2 2 2 0 SlyX Rho_Binding PF08912.6 EMR67957.1 - 0.86 9.9 11.9 1.5 9.1 0.5 2.5 2 1 0 2 2 2 0 Rho Binding DUF848 PF05852.6 EMR67957.1 - 0.9 9.3 5.5 4.4 7.1 0.9 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TMPIT PF07851.8 EMR67957.1 - 0.95 8.4 5.6 1.2 8.1 3.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.1 EMR67957.1 - 1 8.5 8.4 1.4 8.0 5.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 FlaC_arch PF05377.6 EMR67957.1 - 1 9.2 7.8 1.4 8.8 0.8 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.7 EMR67957.1 - 1.3 8.7 15.6 7.1 6.3 9.2 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein MIP-T3 PF10243.4 EMR67957.1 - 1.4 7.2 12.6 0.015 13.7 2.9 1.7 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 GAS PF13851.1 EMR67957.1 - 1.4 8.0 11.7 0.71 9.0 2.8 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3375 PF11855.3 EMR67957.1 - 1.4 7.5 6.7 0.58 8.8 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) Spectrin PF00435.16 EMR67957.1 - 1.5 9.1 9.1 25 5.2 6.2 2.2 1 1 0 1 1 1 0 Spectrin repeat Hrs_helical PF12210.3 EMR67957.1 - 1.5 9.1 5.5 0.95 9.7 1.1 2.1 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF3847 PF12958.2 EMR67957.1 - 1.5 8.5 11.6 3.8 7.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) CENP-F_N PF10481.4 EMR67957.1 - 1.6 8.0 11.2 3.7 6.8 7.8 1.6 1 1 0 1 1 1 0 Cenp-F N-terminal domain Filament PF00038.16 EMR67957.1 - 1.6 8.1 11.0 18 4.6 2.6 1.8 1 1 0 1 1 1 0 Intermediate filament protein AAA_13 PF13166.1 EMR67957.1 - 2 6.7 10.4 10 4.4 7.2 1.7 1 1 0 1 1 1 0 AAA domain GrpE PF01025.14 EMR67957.1 - 2.1 7.8 10.5 4.2 6.8 1.0 2.1 2 0 0 2 2 2 0 GrpE PCRF PF03462.13 EMR67957.1 - 2.2 8.0 5.5 5 6.8 0.3 2.2 2 0 0 2 2 2 0 PCRF domain CENP-Q PF13094.1 EMR67957.1 - 2.5 8.1 10.7 5.1 7.1 7.4 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1090 PF06476.7 EMR67957.1 - 2.9 7.5 8.8 0.76 9.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) Osmo_CC PF08946.5 EMR67957.1 - 3 7.9 13.1 0.074 13.0 2.9 2.6 2 1 0 2 2 2 0 Osmosensory transporter coiled coil Kinetocho_Slk19 PF12709.2 EMR67957.1 - 3.4 7.7 9.7 3.4 7.8 1.8 2.5 2 1 0 2 2 2 0 Central kinetochore-associated ACCA PF03255.9 EMR67957.1 - 3.7 7.0 6.4 12 5.4 0.3 2.1 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Rootletin PF15035.1 EMR67957.1 - 4.1 7.3 11.9 33 4.3 8.2 2.1 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Spc24 PF08286.6 EMR67957.1 - 4.1 7.1 10.5 3 7.5 3.1 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 OmpH PF03938.9 EMR67957.1 - 4.2 7.2 18.3 6.4 6.6 0.6 2.1 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Laminin_I PF06008.9 EMR67957.1 - 4.5 6.5 10.6 19 4.4 7.3 1.8 1 1 0 1 1 1 0 Laminin Domain I YlqD PF11068.3 EMR67957.1 - 4.8 7.2 17.3 1.5 8.8 1.6 2.0 1 1 1 2 2 2 0 YlqD protein Syntaxin PF00804.20 EMR67957.1 - 5.2 7.2 12.8 2.2e+02 2.0 8.7 2.1 1 1 0 1 1 1 0 Syntaxin FlxA PF14282.1 EMR67957.1 - 5.8 6.9 15.3 2.1 8.3 1.3 2.2 2 0 0 2 2 2 0 FlxA-like protein Val_tRNA-synt_C PF10458.4 EMR67957.1 - 5.8 7.0 12.2 0.41 10.7 0.5 2.8 3 0 0 3 3 2 0 Valyl tRNA synthetase tRNA binding arm Cluap1 PF10234.4 EMR67957.1 - 5.9 6.0 11.7 1.3 8.1 0.6 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF2968 PF11180.3 EMR67957.1 - 6 6.1 11.3 6.7 6.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Macoilin PF09726.4 EMR67957.1 - 6.7 4.8 11.3 9.3 4.3 7.8 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF1640 PF07798.6 EMR67957.1 - 6.7 6.7 13.2 14 5.6 9.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4407 PF14362.1 EMR67957.1 - 6.8 5.5 10.2 21 3.9 7.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) THOC7 PF05615.8 EMR67957.1 - 7.7 6.7 11.8 7.7 6.7 2.1 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 Phage_GP20 PF06810.6 EMR67957.1 - 7.7 5.9 13.3 0.6 9.5 1.3 2.1 1 1 0 2 2 2 0 Phage minor structural protein GP20 Cauli_AT PF03233.8 EMR67957.1 - 8.3 6.0 7.6 7.5 6.2 1.3 2.1 1 1 1 2 2 2 0 Aphid transmission protein FemAB PF02388.11 EMR67957.1 - 9 4.8 12.3 5.5 5.5 1.0 2.0 1 1 1 2 2 2 0 FemAB family Rab5-bind PF09311.6 EMR67957.1 - 9.4 6.0 13.6 2.4e+02 1.5 9.4 2.3 1 1 0 1 1 1 0 Rabaptin-like protein Atg14 PF10186.4 EMR67957.1 - 9.5 5.0 13.5 25 3.6 9.4 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Lge1 PF11488.3 EMR67957.1 - 10 6.4 8.3 2.4e+02 1.9 5.7 2.3 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 RHS_repeat PF05593.9 EMR67958.1 - 2.8e-16 59.2 69.8 1.4e-05 25.1 0.3 14.5 13 2 2 15 15 15 7 RHS Repeat DUF4626 PF15422.1 EMR67958.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4626) PPO1_DWL PF12142.3 EMR67958.1 - 0.22 11.0 9.3 2.9 7.4 0.0 5.2 5 0 0 5 5 5 0 Polyphenol oxidase middle domain DUF3836 PF12930.2 EMR67958.1 - 0.4 10.1 3.6 7.4 6.0 0.0 3.7 4 1 0 4 4 4 0 Family of unknown function (DUF3836) HSP70 PF00012.15 EMR67959.1 - 1.5e-05 23.1 0.0 0.00022 19.2 0.0 2.1 2 1 0 2 2 2 2 Hsp70 protein PAP1 PF08601.5 EMR67960.1 - 0.17 11.5 19.1 0.29 10.7 13.3 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 RAP1 PF07218.6 EMR67960.1 - 0.71 7.8 6.7 0.95 7.4 4.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CytochromB561_N PF09786.4 EMR67960.1 - 5.5 5.3 15.8 7.6 4.8 10.9 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal JAB PF01398.16 EMR67961.1 - 1.2e-14 53.9 0.0 2.1e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EMR67961.1 - 5.2e-07 29.1 0.0 1.4e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 EMR67961.1 - 9.7e-06 25.5 0.1 1.8e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain AAA PF00004.24 EMR67962.1 - 5.3e-42 143.1 0.0 1e-41 142.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EMR67962.1 - 3e-27 94.2 0.7 1.2e-26 92.3 0.0 2.5 3 0 0 3 3 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EMR67962.1 - 1.5e-21 76.0 9.5 3.3e-21 74.9 5.9 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EMR67962.1 - 2.8e-05 24.9 0.2 0.00013 22.7 0.0 2.3 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EMR67962.1 - 4.4e-05 22.6 0.0 9.2e-05 21.5 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EMR67962.1 - 6.6e-05 22.4 0.0 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 EMR67962.1 - 6.7e-05 22.6 0.0 0.00047 19.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMR67962.1 - 6.8e-05 23.0 0.1 0.0072 16.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EMR67962.1 - 7.1e-05 22.9 0.9 0.013 15.6 0.0 3.1 4 0 0 4 4 3 1 RNA helicase AAA_14 PF13173.1 EMR67962.1 - 9.8e-05 22.2 0.0 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMR67962.1 - 0.00011 22.0 0.0 0.00031 20.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EMR67962.1 - 0.00017 20.4 0.0 0.00032 19.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EMR67962.1 - 0.00023 20.6 0.4 0.58 9.5 0.1 3.2 1 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EMR67962.1 - 0.0003 20.8 0.5 0.016 15.2 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 EMR67962.1 - 0.0014 17.6 0.0 0.0044 15.9 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 EMR67962.1 - 0.002 18.0 0.0 0.0074 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 EMR67962.1 - 0.0023 17.5 0.6 0.023 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMR67962.1 - 0.0056 15.7 1.5 0.12 11.4 0.1 2.9 2 1 0 2 2 1 1 Zeta toxin Mg_chelatase PF01078.16 EMR67962.1 - 0.0099 15.0 0.6 0.029 13.5 0.0 2.0 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EMR67962.1 - 0.028 13.6 1.0 0.07 12.3 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Arch_ATPase PF01637.13 EMR67962.1 - 0.033 13.8 0.0 0.93 9.1 0.0 2.5 1 1 1 2 2 2 0 Archaeal ATPase ResIII PF04851.10 EMR67962.1 - 0.034 13.9 0.1 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit USP8_dimer PF08969.6 EMR67962.1 - 0.042 13.8 8.2 0.022 14.7 3.6 2.0 2 0 0 2 2 2 0 USP8 dimerisation domain Torsin PF06309.6 EMR67962.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Torsin NACHT PF05729.7 EMR67962.1 - 0.066 12.8 0.0 0.53 9.9 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_18 PF13238.1 EMR67962.1 - 0.072 13.4 0.1 0.2 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.1 EMR67962.1 - 0.077 12.7 0.0 0.26 11.0 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Parvo_NS1 PF01057.12 EMR67962.1 - 0.12 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 EMR67962.1 - 0.13 11.3 0.0 11 4.9 0.0 2.3 1 1 1 2 2 2 0 KaiC ABC_tran PF00005.22 EMR67962.1 - 0.13 12.5 1.0 2.5 8.3 0.0 3.1 3 1 0 3 3 3 0 ABC transporter TPR_1 PF00515.23 EMR67962.1 - 2.5 7.8 5.9 2.3 7.9 2.5 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF3632 PF12311.3 EMR67964.1 - 2.7e-17 63.1 0.2 2.7e-17 63.1 0.1 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3632) YchF-GTPase_C PF06071.8 EMR67965.1 - 4.6e-34 116.0 0.1 1.1e-33 114.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EMR67965.1 - 2e-12 47.0 0.0 6.6e-12 45.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMR67965.1 - 0.00059 19.1 0.0 0.0013 18.0 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_23 PF13476.1 EMR67965.1 - 0.012 15.9 3.5 0.15 12.3 2.4 2.1 1 1 0 1 1 1 0 AAA domain TGS PF02824.16 EMR67965.1 - 0.014 15.2 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 TGS domain AAA_14 PF13173.1 EMR67965.1 - 0.019 14.8 0.0 0.051 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EMR67965.1 - 0.026 14.2 0.5 3.7 7.2 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EMR67965.1 - 0.064 13.5 0.3 15 5.9 0.5 2.4 2 0 0 2 2 2 0 AAA domain BetaGal_dom3 PF13363.1 EMR67965.1 - 0.065 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 AAA_17 PF13207.1 EMR67965.1 - 0.077 13.8 0.1 0.36 11.6 0.1 2.4 1 1 0 1 1 1 0 AAA domain DNA_pol3_a_NII PF11490.3 EMR67965.1 - 1.8 8.1 8.6 6.7 6.3 0.2 3.3 2 1 1 3 3 3 0 DNA polymerase III polC-type N-terminus II DUF3833 PF12915.2 EMR67966.1 - 0.098 11.8 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3833) FMO-like PF00743.14 EMR67967.1 - 1.8e-31 108.9 0.0 8.6e-24 83.6 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMR67967.1 - 3.8e-14 53.2 0.0 8e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR67967.1 - 3.2e-08 33.6 0.0 1e-06 28.7 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR67967.1 - 9.5e-07 28.7 0.1 4.9e-06 26.4 0.1 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EMR67967.1 - 0.00047 20.1 0.0 0.00094 19.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMR67967.1 - 0.0045 16.1 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EMR67967.1 - 0.0066 15.3 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR67967.1 - 0.0072 15.2 0.1 1.3 7.7 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 EMR67967.1 - 0.069 11.6 0.0 0.13 10.7 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 EMR67967.1 - 0.12 11.4 0.0 1.7 7.7 0.0 2.3 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EMR67967.1 - 0.12 12.7 0.0 5.1 7.5 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FYDLN_acid PF09538.5 EMR67968.1 - 0.25 11.9 43.0 0.46 11.0 2.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) CDC45 PF02724.9 EMR67968.1 - 4.3 5.2 40.1 0.059 11.3 10.9 3.1 3 0 0 3 3 3 0 CDC45-like protein Sigma70_ner PF04546.8 EMR67968.1 - 6.9 6.2 44.7 0.13 11.9 12.0 3.5 3 0 0 3 3 3 0 Sigma-70, non-essential region PRTP PF01366.13 EMR67968.1 - 8.1 4.3 8.2 0.26 9.2 1.5 1.4 2 0 0 2 2 2 0 Herpesvirus processing and transport protein Pox_Ag35 PF03286.9 EMR67968.1 - 8.5 5.8 31.2 5.8 6.3 1.7 3.3 3 0 0 3 3 3 0 Pox virus Ag35 surface protein Fungal_trans_2 PF11951.3 EMR67969.1 - 2.6e-09 36.1 0.1 0.0011 17.7 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Amino_oxidase PF01593.19 EMR67970.1 - 2.1e-45 155.6 0.1 4e-44 151.4 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMR67970.1 - 3e-12 46.3 0.3 7e-12 45.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR67970.1 - 5.4e-05 22.2 0.7 0.0002 20.3 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR67970.1 - 0.00016 20.6 0.2 0.00032 19.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EMR67970.1 - 0.00044 19.4 0.4 0.00071 18.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMR67970.1 - 0.0014 17.1 0.1 0.0024 16.4 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EMR67970.1 - 0.0066 16.3 0.1 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR67970.1 - 0.0094 16.3 0.1 0.025 14.9 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR67970.1 - 0.012 15.6 0.1 0.091 12.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR67970.1 - 0.06 13.1 0.4 0.9 9.2 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EMR67970.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase MIF4G PF02854.14 EMR67970.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 MIF4G domain Trp_halogenase PF04820.9 EMR67970.1 - 0.32 9.5 1.6 0.42 9.1 0.1 1.9 3 0 0 3 3 3 0 Tryptophan halogenase Peptidase_C97 PF05903.9 EMR67971.1 - 2.8e-32 111.6 0.0 3.4e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EMR67971.1 - 0.0018 18.2 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Pyr_redox_3 PF13738.1 EMR67972.1 - 5.2e-19 69.1 6.0 9.1e-17 61.7 0.0 3.9 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR67972.1 - 5.4e-10 38.0 0.9 3e-09 35.6 0.1 2.3 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMR67972.1 - 4.7e-08 32.3 5.8 4.1e-07 29.2 0.1 3.1 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EMR67972.1 - 1.4e-06 27.4 4.7 0.026 13.4 0.0 3.3 2 2 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR67972.1 - 1.4e-06 28.2 0.0 0.018 14.9 0.0 4.0 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR67972.1 - 0.14 12.1 0.5 0.38 10.7 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EMR67972.1 - 0.18 11.9 0.0 16 5.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EMR67972.1 - 0.2 10.6 1.1 0.43 9.5 0.6 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 EMR67972.1 - 0.46 10.2 3.8 0.76 9.5 0.1 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding Nitroreductase PF00881.19 EMR67974.1 - 8.5e-27 93.9 0.0 1e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.1 EMR67974.1 - 0.016 14.3 0.0 0.52 9.4 0.0 2.6 2 1 1 3 3 3 0 Putative TM nitroreductase Ribosomal_S11 PF00411.14 EMR67975.1 - 2.1e-11 43.9 0.1 3.7e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 DUF4160 PF13711.1 EMR67975.1 - 0.022 14.6 0.2 0.045 13.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) Tim44 PF04280.10 EMR67976.1 - 1.3e-33 116.0 0.1 5.3e-33 114.0 0.0 2.1 2 0 0 2 2 2 1 Tim44-like domain Mito_fiss_reg PF05308.6 EMR67976.1 - 1.3 8.2 7.0 2.5 7.4 4.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator adh_short PF00106.20 EMR67977.1 - 5.7e-16 58.8 0.0 8.2e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EMR67977.1 - 2e-06 27.7 0.0 0.0055 16.4 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR67977.1 - 0.0017 18.0 0.0 0.033 13.8 0.0 2.1 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.14 EMR67977.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hydro_47 PF01532.15 EMR67978.1 - 5.6e-67 226.3 0.0 1.1e-58 199.0 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 AAA_11 PF13086.1 EMR67979.1 - 5.2e-59 199.6 0.6 4.2e-58 196.7 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EMR67979.1 - 1.4e-56 191.0 0.0 4.8e-56 189.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMR67979.1 - 6.8e-13 48.1 0.0 2.3e-12 46.4 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EMR67979.1 - 9.2e-11 41.6 0.0 5e-09 36.0 0.0 2.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EMR67979.1 - 4.1e-09 36.5 0.0 1.5e-08 34.6 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EMR67979.1 - 5.4e-08 32.6 0.0 0.18 11.2 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EMR67979.1 - 1.3e-06 27.6 0.1 5e-06 25.7 0.1 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EMR67979.1 - 7.3e-06 25.4 0.1 1.6e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 EMR67979.1 - 1.5e-05 25.1 0.2 0.00069 19.7 0.1 2.7 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EMR67979.1 - 0.00035 19.5 0.0 0.00066 18.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD_C PF13361.1 EMR67979.1 - 0.002 17.6 0.2 2.5 7.4 0.0 3.2 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain Zot PF05707.7 EMR67979.1 - 0.0023 17.4 0.1 0.075 12.5 0.0 2.9 2 1 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_25 PF13481.1 EMR67979.1 - 0.0023 17.3 0.0 0.08 12.3 0.0 2.8 2 1 0 3 3 3 1 AAA domain 4HB_MCP_1 PF12729.2 EMR67979.1 - 0.0027 17.0 0.2 0.0066 15.8 0.2 1.6 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction IstB_IS21 PF01695.12 EMR67979.1 - 0.0032 16.9 0.0 0.0098 15.3 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EMR67979.1 - 0.0032 17.4 0.0 0.0097 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 EMR67979.1 - 0.0033 16.6 0.0 0.045 12.9 0.0 2.5 3 0 0 3 3 3 1 PhoH-like protein Flavi_DEAD PF07652.9 EMR67979.1 - 0.0059 16.3 0.3 0.026 14.3 0.0 2.2 2 1 1 3 3 2 1 Flavivirus DEAD domain AAA PF00004.24 EMR67979.1 - 0.0097 16.1 0.1 0.11 12.6 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EMR67979.1 - 0.02 14.6 0.9 6.5 6.4 0.0 3.2 3 0 0 3 3 3 0 NTPase FtsK_SpoIIIE PF01580.13 EMR67979.1 - 0.04 13.3 0.0 0.099 12.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EMR67979.1 - 0.041 13.3 0.0 0.18 11.2 0.0 2.0 1 1 1 2 2 2 0 AAA-like domain AAA_5 PF07728.9 EMR67979.1 - 0.041 13.5 0.1 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 EMR67979.1 - 0.043 12.4 0.0 0.079 11.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.22 EMR67979.1 - 0.05 13.9 0.0 0.17 12.1 0.0 2.0 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 EMR67979.1 - 0.19 12.5 1.5 0.58 10.9 0.4 2.5 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EMR67979.1 - 8.1 6.7 7.5 2.2 8.6 0.9 3.0 3 1 0 3 3 3 0 AAA domain HTH_32 PF13565.1 EMR67980.1 - 0.041 14.6 2.5 0.06 14.1 0.2 1.9 1 1 1 2 2 2 0 Homeodomain-like domain Med13_C PF06333.7 EMR67982.1 - 1.2e-51 175.6 0.4 2.1e-48 164.9 0.1 2.4 1 1 1 2 2 2 2 Mediator complex subunit 13 C-terminal PNP_UDP_1 PF01048.15 EMR67983.1 - 4.3e-23 81.5 0.1 5.5e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF3677 PF12432.3 EMR67983.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) VWA_2 PF13519.1 EMR67984.1 - 0.034 14.2 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain FAT PF02259.18 EMR67986.1 - 4.2e-129 430.5 0.8 8.4e-129 429.5 0.6 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EMR67986.1 - 1.3e-62 211.3 0.2 2.5e-62 210.4 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EMR67986.1 - 2.8e-55 186.6 1.0 6.5e-51 172.4 0.1 5.3 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EMR67986.1 - 5.8e-44 148.2 1.1 3.3e-43 145.8 0.1 3.0 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 EMR67986.1 - 8e-16 58.1 10.9 0.0025 18.0 0.1 8.2 7 1 0 8 8 7 4 HEAT repeats FATC PF02260.15 EMR67986.1 - 1e-13 50.4 0.1 2.2e-13 49.3 0.1 1.6 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 EMR67986.1 - 7.4e-13 48.5 13.9 5.4e-05 23.5 0.0 11.7 9 2 2 11 11 11 2 HEAT-like repeat HEAT PF02985.17 EMR67986.1 - 3.2e-10 39.1 19.8 0.023 14.7 0.0 10.9 11 0 0 11 11 11 3 HEAT repeat Adaptin_N PF01602.15 EMR67986.1 - 2.4e-06 26.1 7.7 0.0053 15.1 0.1 4.3 3 2 0 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EMR67986.1 - 3.2e-06 27.4 0.3 25 5.3 0.0 7.1 6 1 1 7 7 7 0 Vacuolar 14 Fab1-binding region UME PF08064.8 EMR67986.1 - 5.1e-05 23.1 1.3 3.5 7.6 0.0 5.3 5 0 0 5 5 5 2 UME (NUC010) domain VirDNA-topo-I_N PF09266.5 EMR67986.1 - 0.086 12.7 0.2 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal F-box PF00646.28 EMR67987.1 - 1.9e-05 24.1 0.1 3.6e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMR67987.1 - 0.0004 20.0 0.2 0.00088 18.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.11 EMR67988.1 - 7.6e-25 87.3 38.3 1.2e-19 70.2 5.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR67988.1 - 2e-07 29.9 0.2 2e-07 29.9 0.1 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EMR67988.1 - 1.8e-06 26.6 13.4 0.004 15.6 0.0 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 EMR67988.1 - 1 7.4 16.6 1.8 6.5 0.1 3.0 2 1 1 3 3 3 0 Transmembrane secretion effector NUC153 PF08159.7 EMR67990.1 - 2.7e-11 42.8 3.1 6.3e-11 41.6 2.2 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EMR67990.1 - 1.4e-08 34.2 0.0 2.1e-06 27.3 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat Glyco_hydro_71 PF03659.9 EMR67991.1 - 6.4e-112 373.8 4.9 7.9e-112 373.5 3.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Iron_transport PF10634.4 EMR67992.1 - 0.019 14.8 0.1 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Fe2+ transport protein PRKCSH-like PF12999.2 EMR67993.1 - 9.1e-39 132.8 8.6 2.2e-23 82.7 0.7 3.3 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EMR67993.1 - 2.4e-31 108.2 0.6 2.4e-31 108.2 0.4 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EMR67993.1 - 1.1e-11 45.3 0.4 3.1e-11 43.9 0.3 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Osmo_CC PF08946.5 EMR67993.1 - 0.015 15.3 2.3 0.015 15.3 1.6 2.6 3 0 0 3 3 2 0 Osmosensory transporter coiled coil Ldl_recept_a PF00057.13 EMR67993.1 - 0.017 15.0 1.3 0.017 15.0 0.9 2.3 2 0 0 2 2 1 0 Low-density lipoprotein receptor domain class A TolA PF06519.6 EMR67993.1 - 0.018 15.0 0.0 0.095 12.6 0.0 2.1 2 0 0 2 2 2 0 TolA C-terminal Prominin PF05478.6 EMR67993.1 - 0.02 12.4 0.6 0.027 12.0 0.4 1.1 1 0 0 1 1 1 0 Prominin DUF3435 PF11917.3 EMR67993.1 - 0.067 11.9 5.7 2.3 6.8 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) DUF3584 PF12128.3 EMR67993.1 - 0.087 10.1 14.6 0.0039 14.5 6.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Syntaxin-18_N PF10496.4 EMR67993.1 - 0.38 10.6 3.3 23 4.9 0.5 2.9 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Effector_1 PF04518.7 EMR67993.1 - 0.38 9.6 4.1 0.76 8.6 0.4 2.1 2 0 0 2 2 2 0 Effector from type III secretion system Prefoldin_2 PF01920.15 EMR67993.1 - 0.5 10.1 17.0 0.032 14.0 2.5 3.7 4 0 0 4 4 3 0 Prefoldin subunit Herpes_UL6 PF01763.11 EMR67993.1 - 0.7 7.9 4.1 0.74 7.9 2.1 1.5 1 1 1 2 2 2 0 Herpesvirus UL6 like FliD_C PF07195.7 EMR67993.1 - 1.9 7.7 6.4 10 5.3 1.0 2.9 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus NuA4 PF09340.5 EMR67993.1 - 2 8.0 11.0 0.54 9.9 0.2 3.3 4 0 0 4 4 3 0 Histone acetyltransferase subunit NuA4 DivIC PF04977.10 EMR67993.1 - 2.1 7.8 12.8 0.14 11.6 2.7 3.1 3 0 0 3 3 3 0 Septum formation initiator DUF4200 PF13863.1 EMR67993.1 - 2.9 7.8 20.8 0.099 12.5 8.5 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 EMR67993.1 - 3 5.5 3.4 4.3 5.0 2.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 EMR67993.1 - 4.2 6.2 15.6 3.7 6.4 7.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Mnd1 PF03962.10 EMR67993.1 - 5.6 6.5 16.0 0.85 9.2 4.4 2.8 3 0 0 3 3 3 0 Mnd1 family PspA_IM30 PF04012.7 EMR67993.1 - 6.8 5.9 17.1 0.47 9.7 7.6 2.2 2 1 0 2 2 2 0 PspA/IM30 family Rtf2 PF04641.7 EMR67994.1 - 1.3e-49 168.7 3.6 1.6e-49 168.4 2.5 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EMR67994.1 - 0.00087 19.0 0.0 0.0039 16.9 0.0 2.1 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EMR67994.1 - 0.0038 16.9 0.0 0.012 15.3 0.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EMR67994.1 - 0.031 13.7 0.2 0.32 10.5 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 EMR67994.1 - 0.062 13.0 0.1 0.44 10.3 0.1 2.2 1 1 1 2 2 2 0 zinc-RING finger domain UPF0547 PF10571.4 EMR67994.1 - 0.44 10.2 3.1 17 5.2 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF2201_N PF13203.1 EMR67994.1 - 1.5 7.8 5.8 2.1 7.4 4.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Ank_2 PF12796.2 EMR67995.1 - 8.6e-76 250.3 17.5 9.7e-15 54.6 0.5 6.9 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EMR67995.1 - 5.5e-57 186.8 27.4 1.6e-07 30.8 0.0 12.5 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 EMR67995.1 - 8.7e-50 166.2 19.6 2.8e-11 43.5 0.0 9.0 3 3 4 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR67995.1 - 3.9e-45 150.8 21.1 4.8e-09 36.1 0.0 10.0 4 3 7 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR67995.1 - 1.6e-41 136.1 16.2 0.00034 20.5 0.0 12.3 12 0 0 12 12 12 9 Ankyrin repeat RhgB_N PF09284.5 EMR67996.1 - 1.2e-106 355.6 9.7 2.2e-106 354.7 6.7 1.5 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EMR67996.1 - 1e-57 194.4 0.3 1.2e-56 190.9 0.0 2.6 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EMR67996.1 - 5.7e-16 58.4 5.0 1.9e-15 56.7 3.5 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EMR67996.1 - 9.1e-05 22.4 4.7 9.1e-05 22.4 3.2 3.3 4 0 0 4 4 4 1 Carboxypeptidase regulatory-like domain Kelch_6 PF13964.1 EMR67996.1 - 2.2 8.6 6.3 1.6 9.0 0.1 3.2 3 0 0 3 3 3 0 Kelch motif DUF4430 PF14478.1 EMR67996.1 - 4.5 7.4 7.3 32 4.6 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4430) MBOAT_2 PF13813.1 EMR67997.1 - 8.4e-09 35.3 0.9 2e-08 34.1 0.6 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Pex24p PF06398.6 EMR67998.1 - 8e-92 307.7 0.0 1e-91 307.4 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin GCIP PF13324.1 EMR67999.1 - 6.1e-05 22.3 0.7 6.1e-05 22.3 0.5 1.6 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting AAA PF00004.24 EMR68000.1 - 0.087 13.0 0.1 0.1 12.7 0.0 1.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ank_2 PF12796.2 EMR68002.1 - 1.3e-26 92.7 0.0 1.9e-13 50.5 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMR68002.1 - 1.7e-26 90.6 0.3 6.5e-07 28.8 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EMR68002.1 - 1.9e-22 78.7 3.0 1.1e-09 38.2 0.0 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR68002.1 - 4.7e-19 66.5 0.1 0.00052 20.0 0.0 5.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EMR68002.1 - 2.2e-18 66.2 0.6 6.8e-13 48.7 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) NACHT PF05729.7 EMR68002.1 - 6.4e-11 42.1 0.0 1.9e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 NACHT domain KAP_NTPase PF07693.9 EMR68002.1 - 0.00025 20.1 0.0 0.00063 18.8 0.0 1.7 2 0 0 2 2 2 1 KAP family P-loop domain AAA_22 PF13401.1 EMR68002.1 - 0.0073 16.4 0.2 0.07 13.2 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EMR68002.1 - 0.024 14.3 0.2 0.15 11.8 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain DUF1841 PF08897.6 EMR68002.1 - 0.072 12.9 0.0 5.3 6.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1841) Sds3 PF08598.6 EMR68008.1 - 3.2e-48 163.9 1.2 5.4e-48 163.2 0.8 1.5 1 1 0 1 1 1 1 Sds3-like UQ_con PF00179.21 EMR68009.1 - 9.5e-09 34.8 0.0 2.4e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMR68009.1 - 0.0022 17.7 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF1590 PF07629.6 EMR68010.1 - 6 6.5 9.5 15 5.2 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1590) COG5 PF10392.4 EMR68011.1 - 0.4 10.6 4.5 0.37 10.7 0.5 2.8 3 1 0 3 3 3 0 Golgi transport complex subunit 5 TMF_DNA_bd PF12329.3 EMR68011.1 - 8.4 6.2 9.0 11 5.9 0.3 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Peptidase_M24 PF00557.19 EMR68012.1 - 5.1e-59 199.3 0.0 1.6e-58 197.6 0.0 1.7 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EMR68012.1 - 1.3e-06 27.8 0.0 3.8e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain SH3_1 PF00018.23 EMR68013.1 - 1.4e-14 53.1 0.1 2.2e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMR68013.1 - 2.1e-12 46.3 0.1 3.3e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMR68013.1 - 1e-08 34.5 0.0 1.7e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ribosomal_L14e PF01929.12 EMR68014.1 - 4.8e-26 90.9 3.0 6.5e-26 90.4 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EMR68014.1 - 0.024 14.3 0.3 0.056 13.1 0.0 1.7 2 0 0 2 2 2 0 KOW motif GMC_oxred_N PF00732.14 EMR68015.1 - 1.4e-64 218.1 0.0 1.7e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR68015.1 - 1.7e-34 119.1 0.0 3e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMR68015.1 - 2.7e-07 29.7 0.1 1.9e-06 27.0 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR68015.1 - 1.5e-06 27.3 0.1 0.00048 19.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR68015.1 - 8e-06 26.0 0.0 0.02 14.9 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR68015.1 - 0.00012 21.1 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMR68015.1 - 0.00013 21.9 0.1 0.00033 20.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR68015.1 - 0.005 16.7 0.0 0.04 13.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR68015.1 - 0.056 11.8 0.0 0.11 10.9 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EMR68015.1 - 0.18 10.8 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Peptidase_A4 PF01828.12 EMR68016.1 - 3.7e-22 78.4 0.1 5.3e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase A4 family YIF1 PF03878.10 EMR68017.1 - 6.9e-78 261.1 1.7 8.2e-78 260.8 1.2 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EMR68017.1 - 0.39 10.2 11.6 0.14 11.6 5.9 1.7 1 1 1 2 2 2 0 Yip1 domain zf-MYND PF01753.13 EMR68018.1 - 0.0012 18.6 3.6 0.0032 17.2 2.5 1.8 1 1 0 1 1 1 1 MYND finger NAC PF01849.13 EMR68020.1 - 2.3e-25 87.8 0.1 5.1e-25 86.7 0.1 1.6 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 EMR68020.1 - 0.00068 19.4 0.1 0.0014 18.4 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EBV-NA3 PF05009.7 EMR68020.1 - 1.4 8.1 9.3 0.58 9.3 0.7 2.3 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CENP-B_dimeris PF09026.5 EMR68020.1 - 8.5 6.6 15.4 16 5.7 0.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TPR_11 PF13414.1 EMR68021.1 - 1e-14 53.9 1.7 1.4e-06 27.8 0.5 4.5 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.1 EMR68021.1 - 2.4e-07 30.5 1.3 0.0015 18.3 0.0 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMR68021.1 - 3e-07 29.8 3.4 0.028 14.3 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR68021.1 - 3.3e-06 27.3 0.5 0.0048 17.2 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMR68021.1 - 0.00077 19.0 7.3 0.15 11.8 0.2 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMR68021.1 - 0.0012 19.4 0.1 1.2 9.8 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMR68021.1 - 0.0013 18.2 0.2 0.039 13.5 0.1 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMR68021.1 - 0.0031 18.0 0.4 16 6.5 0.0 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat NACHT PF05729.7 EMR68021.1 - 0.0076 15.9 0.0 0.058 13.0 0.0 2.5 1 1 0 1 1 1 1 NACHT domain JHBP PF06585.6 EMR68021.1 - 0.015 14.1 0.5 0.2 10.4 0.2 2.4 2 0 0 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) AAA_22 PF13401.1 EMR68021.1 - 0.016 15.3 0.2 0.33 11.1 0.0 3.2 3 1 0 3 3 3 0 AAA domain TPR_7 PF13176.1 EMR68021.1 - 0.016 14.9 0.0 45 4.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMR68021.1 - 0.029 14.5 1.8 21 5.6 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_16 PF13191.1 EMR68021.1 - 0.036 14.0 0.0 0.47 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Apc5 PF12862.2 EMR68021.1 - 0.063 13.1 0.0 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 AAA_19 PF13245.1 EMR68021.1 - 0.086 12.5 0.0 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain TPR_6 PF13174.1 EMR68021.1 - 0.9 10.1 5.3 12 6.5 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Choline_kinase PF01633.15 EMR68022.1 - 0.44 10.0 7.6 0.43 10.1 1.3 2.2 1 1 0 2 2 2 0 Choline/ethanolamine kinase Mt_ATP-synt_D PF05873.7 EMR68023.1 - 1.9e-18 66.6 0.8 2.2e-18 66.3 0.6 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) TRADD_N PF09034.5 EMR68023.1 - 0.021 14.8 0.1 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 TRADD, N-terminal domain Peptidase_S8 PF00082.17 EMR68024.1 - 8.2e-58 195.7 0.2 1.4e-57 194.9 0.1 1.4 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EMR68024.1 - 2.5e-08 34.3 0.1 5.4e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Aldo_ket_red PF00248.16 EMR68025.1 - 2.1e-44 151.4 0.0 2.4e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HD_5 PF13487.1 EMR68025.1 - 0.13 12.2 0.0 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 HD domain IncA PF04156.9 EMR68026.1 - 0.02 14.5 0.1 0.02 14.5 0.1 1.9 3 0 0 3 3 3 0 IncA protein Mpv17_PMP22 PF04117.7 EMR68027.1 - 2e-12 46.5 5.2 1.6e-11 43.6 0.2 2.4 2 0 0 2 2 2 2 Mpv17 / PMP22 family GtrA PF04138.9 EMR68027.1 - 0.89 9.5 6.9 0.12 12.3 0.3 2.4 2 1 0 2 2 2 0 GtrA-like protein IU_nuc_hydro PF01156.14 EMR68029.1 - 8.7e-08 31.7 0.0 1.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase F-box-like PF12937.2 EMR68030.1 - 1.1e-07 31.4 0.1 4.6e-07 29.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMR68030.1 - 0.29 10.8 1.8 0.63 9.7 0.1 2.5 3 0 0 3 3 3 0 F-box domain MFS_1 PF07690.11 EMR68031.1 - 7.1e-23 80.8 33.9 7.1e-23 80.8 23.5 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR68031.1 - 0.00054 18.2 5.1 0.001 17.3 3.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 EMR68032.1 - 0.00023 21.1 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR68032.1 - 0.0032 17.2 0.1 0.0085 15.8 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase SRP-alpha_N PF04086.8 EMR68033.1 - 5.4e-78 262.1 0.0 9.6e-78 261.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EMR68033.1 - 1e-46 158.8 0.2 3.4e-45 153.9 0.1 2.4 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ArgK PF03308.11 EMR68033.1 - 6.4e-07 28.4 0.1 1.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 ArgK protein SRP54_N PF02881.14 EMR68033.1 - 9e-07 28.9 0.2 3.6e-06 26.9 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 EMR68033.1 - 1.8e-05 24.2 0.0 3.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EMR68033.1 - 0.00035 20.2 0.7 0.0069 16.1 0.1 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EMR68033.1 - 0.0019 17.8 0.1 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMR68033.1 - 0.0035 16.7 0.1 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EMR68033.1 - 0.0084 16.0 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EMR68033.1 - 0.018 15.2 0.3 0.4 10.8 0.0 3.0 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.22 EMR68033.1 - 0.04 14.2 0.1 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 EMR68033.1 - 0.056 12.8 0.1 0.16 11.3 0.1 1.8 1 1 0 1 1 1 0 AAA-like domain MmgE_PrpD PF03972.9 EMR68034.1 - 1.1e-147 491.7 0.0 1.3e-147 491.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family KNOX2 PF03791.8 EMR68034.1 - 0.016 14.4 0.1 0.071 12.3 0.0 2.0 2 0 0 2 2 2 0 KNOX2 domain RRM_1 PF00076.17 EMR68036.1 - 7.4e-11 41.5 0.5 9.6e-05 21.9 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR68036.1 - 1.7e-09 37.5 0.1 0.0023 17.8 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 EMR68036.1 - 5.1e-07 29.3 2.9 5.1e-07 29.3 2.0 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EMR68036.1 - 4e-06 26.5 2.4 7.2e-06 25.7 0.5 2.3 2 0 0 2 2 2 1 DExH-box splicing factor binding site zf-RanBP PF00641.13 EMR68036.1 - 2.5e-05 23.2 4.7 4.9e-05 22.3 3.3 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_5 PF13893.1 EMR68036.1 - 8.4e-05 22.3 0.0 0.0049 16.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 EMR68036.1 - 0.021 14.0 0.1 0.021 14.0 0.1 2.5 4 0 0 4 4 4 0 RED-like protein N-terminal region DUF3279 PF11682.3 EMR68036.1 - 0.17 11.4 2.3 0.16 11.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3279) F-box PF00646.28 EMR68037.1 - 6e-05 22.5 0.4 0.00013 21.5 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMR68037.1 - 0.00016 21.3 0.2 0.00039 20.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EMR68037.1 - 0.053 13.4 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 PRANC domain adh_short PF00106.20 EMR68039.1 - 1.6e-16 60.6 3.0 3.2e-15 56.4 2.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR68039.1 - 2.5e-10 40.5 0.3 5.5e-09 36.1 0.2 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMR68039.1 - 0.035 14.1 0.9 0.18 11.7 0.6 2.0 1 1 0 1 1 1 0 NADH(P)-binding CPSF100_C PF13299.1 EMR68040.1 - 8.6e-42 143.0 0.5 1.7e-41 142.0 0.3 1.5 1 1 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.7 EMR68040.1 - 1.4e-05 24.8 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase DASH_Spc19 PF08287.6 EMR68041.1 - 5.4e-42 143.0 0.0 8.1e-42 142.4 0.0 1.3 1 0 0 1 1 1 1 Spc19 Lzipper-MIP1 PF14389.1 EMR68041.1 - 0.0064 16.5 1.9 0.83 9.8 4.2 2.2 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 DUF2917 PF11142.3 EMR68042.1 - 0.1 11.7 0.1 0.29 10.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2917) Yeast-kill-tox PF09207.6 EMR68042.1 - 4 7.9 6.5 5 7.6 2.5 2.0 1 1 1 2 2 2 0 Yeast killer toxin GMC_oxred_C PF05199.8 EMR68043.1 - 1.4e-32 112.9 0.1 1.9e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR68043.1 - 6.2e-20 71.5 0.1 8.5e-20 71.0 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase DNase_NucA_NucB PF14040.1 EMR68044.1 - 1.8e-09 37.7 10.4 3.6e-09 36.7 4.2 2.5 2 1 0 2 2 2 1 Deoxyribonuclease NucA/NucB SH3_1 PF00018.23 EMR68045.1 - 2.6e-09 36.2 0.0 5.2e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMR68045.1 - 3.7e-07 29.5 0.0 6.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EMR68045.1 - 6.1e-07 28.9 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.11 EMR68047.1 - 2.8e-27 95.3 24.0 2.8e-27 95.3 16.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Cu_amine_oxid PF01179.15 EMR68050.1 - 1e-115 386.7 6.0 1.3e-115 386.4 4.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EMR68050.1 - 3.3e-35 119.8 0.4 8e-35 118.5 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EMR68050.1 - 0.0002 21.3 0.0 0.00046 20.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain UCR_14kD PF02271.11 EMR68052.1 - 9.9e-46 153.8 0.1 1.1e-45 153.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Anp1 PF03452.9 EMR68053.1 - 7.4e-101 336.8 0.0 8.9e-101 336.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 HhH-GPD PF00730.20 EMR68054.1 - 8.7e-14 51.7 0.0 5.4e-13 49.1 0.0 2.1 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Mito_carr PF00153.22 EMR68055.1 - 8.1e-35 118.4 0.4 1.2e-22 79.4 0.2 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein LRR_6 PF13516.1 EMR68057.1 - 1.6e-05 24.4 0.3 33 4.9 0.0 6.4 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.2 EMR68057.1 - 0.033 13.8 5.4 0.087 12.4 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) adh_short PF00106.20 EMR68058.1 - 6.7e-15 55.3 0.1 1.2e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68058.1 - 2.6e-05 23.9 0.3 4.5e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR68058.1 - 0.00046 19.6 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMR68058.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Arm PF00514.18 EMR68060.1 - 1.3e-96 313.4 15.1 3.8e-14 51.9 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMR68060.1 - 2.8e-26 91.6 0.2 2.5e-10 40.5 0.0 6.1 1 1 7 8 8 8 7 HEAT repeats HEAT_EZ PF13513.1 EMR68060.1 - 4.9e-23 80.9 9.8 1.2e-09 38.3 0.0 6.3 5 1 2 7 7 7 4 HEAT-like repeat IBB PF01749.15 EMR68060.1 - 6.6e-23 80.6 2.4 1.1e-22 79.9 1.7 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EMR68060.1 - 1.2e-21 74.7 2.1 1.2e-06 28.0 0.0 7.4 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.8 EMR68060.1 - 3.1e-10 39.5 0.0 0.013 14.5 0.0 4.4 3 1 2 5 5 5 3 Armadillo-like Adaptin_N PF01602.15 EMR68060.1 - 1.9e-06 26.5 0.0 0.00063 18.2 0.0 3.1 1 1 2 3 3 3 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EMR68060.1 - 0.00024 20.9 0.0 0.99 9.3 0.0 4.6 2 1 4 6 6 6 2 V-ATPase subunit H HEAT_PBS PF03130.11 EMR68060.1 - 0.00089 19.5 0.3 1.8 9.2 0.0 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 EMR68060.1 - 0.0075 14.5 1.2 0.42 8.8 0.1 3.0 3 1 0 3 3 3 1 Proteasome non-ATPase 26S subunit Glycos_trans_3N PF02885.12 EMR68060.1 - 0.046 13.2 0.0 14 5.3 0.0 3.4 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain DcpS_C PF11969.3 EMR68061.1 - 1.9e-15 57.1 0.0 2.2e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EMR68061.1 - 4.9e-12 46.2 0.6 9.7e-11 42.0 0.4 2.2 1 1 0 1 1 1 1 HIT domain Cyclin_N PF00134.18 EMR68062.1 - 2.7e-41 140.1 0.0 4.5e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMR68062.1 - 3.6e-32 110.7 0.2 2.3e-31 108.1 0.0 2.4 1 1 1 2 2 2 1 Cyclin, C-terminal domain Zn_clus PF00172.13 EMR68063.1 - 0.00025 20.8 12.3 0.00046 20.0 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EMR68064.1 - 1.9e-34 118.9 30.2 2.3e-34 118.6 21.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily AT_hook PF02178.14 EMR68065.1 - 0.021 14.4 4.3 0.021 14.4 2.9 6.2 5 0 0 5 5 5 0 AT hook motif CDC27 PF09507.5 EMR68065.1 - 0.16 11.1 12.4 0.19 10.9 8.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.7 EMR68065.1 - 0.95 7.3 15.1 1.1 7.1 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EMR68065.1 - 4.4 5.6 17.4 5.4 5.3 12.0 1.1 1 0 0 1 1 1 0 Daxx Family HA2 PF04408.18 EMR68066.1 - 5.5e-17 61.6 0.1 1.7e-16 60.0 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EMR68066.1 - 1.6e-14 53.7 0.0 3.2e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EMR68066.1 - 7.6e-12 44.9 0.0 1.9e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMR68066.1 - 4.5e-10 39.2 0.4 2.1e-09 37.1 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.17 EMR68066.1 - 6.8e-09 35.6 0.1 1.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 RWD domain UBA PF00627.26 EMR68066.1 - 2.8e-05 23.7 0.1 0.018 14.9 0.0 3.2 2 0 0 2 2 2 1 UBA/TS-N domain AAA_22 PF13401.1 EMR68066.1 - 6.8e-05 23.0 0.1 0.00018 21.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EMR68066.1 - 0.0018 17.8 0.0 0.0037 16.7 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 EMR68066.1 - 0.0029 17.1 0.0 0.006 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EMR68066.1 - 0.0038 16.6 0.0 0.013 14.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EMR68066.1 - 0.0041 16.9 0.0 0.013 15.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EMR68066.1 - 0.01 14.7 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EMR68066.1 - 0.013 14.5 0.2 0.031 13.4 0.2 1.6 1 1 0 1 1 1 0 KaiC Zot PF05707.7 EMR68066.1 - 0.041 13.3 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_23 PF13476.1 EMR68066.1 - 0.2 11.9 1.8 0.28 11.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain POT1 PF02765.12 EMR68067.1 - 3.3e-09 36.8 0.0 1e-07 31.9 0.0 2.4 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 DUF4283 PF14111.1 EMR68067.1 - 0.022 13.8 0.4 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) TonB_2 PF13103.1 EMR68067.1 - 0.082 12.9 1.0 0.73 9.9 0.1 2.8 2 0 0 2 2 2 0 TonB C terminal Membralin PF09746.4 EMR68067.1 - 0.21 10.6 2.0 0.34 9.9 1.4 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF3824 PF12868.2 EMR68068.1 - 2.1e-09 38.4 31.2 9.1e-09 36.3 14.6 11.9 4 3 7 13 13 13 2 Domain of unknwon function (DUF3824) CopD PF05425.8 EMR68068.1 - 0.11 12.7 0.3 0.94 9.7 0.0 2.5 3 0 0 3 3 3 0 Copper resistance protein D DUF4366 PF14283.1 EMR68068.1 - 0.13 11.6 0.1 0.13 11.6 0.1 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) Rick_17kDa_Anti PF05433.10 EMR68068.1 - 5.7 6.6 25.7 0.083 12.5 5.8 3.5 3 0 0 3 3 3 0 Glycine zipper 2TM domain RAP1 PF07218.6 EMR68068.1 - 8.5 4.3 11.2 16 3.4 7.8 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DnaJ PF00226.26 EMR68069.1 - 7.9e-26 89.5 1.1 1.4e-25 88.7 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EMR68069.1 - 1.5e-14 53.8 15.5 2.5e-14 53.0 10.8 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EMR68069.1 - 2.2e-11 43.4 0.0 5.9e-10 38.9 0.0 2.4 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 EMR68069.1 - 0.006 16.2 6.3 0.54 9.9 0.6 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 EMR68069.1 - 0.91 9.8 8.2 1.3 9.3 0.2 2.9 1 1 2 3 3 3 0 Restriction alleviation protein Lar zf-FPG_IleRS PF06827.9 EMR68069.1 - 0.94 9.1 7.3 2.7 7.7 0.1 3.2 2 1 1 3 3 3 0 Zinc finger found in FPG and IleRS DZR PF12773.2 EMR68069.1 - 8.4 6.3 11.8 7 6.5 2.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon OB_NTP_bind PF07717.11 EMR68070.1 - 1.1e-27 96.0 0.0 3e-27 94.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMR68070.1 - 2.9e-25 88.2 0.1 2.9e-25 88.2 0.1 2.6 4 0 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMR68070.1 - 2e-11 43.5 0.0 4.6e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EMR68070.1 - 3.3e-06 27.2 0.0 1.3e-05 25.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EMR68070.1 - 2.1e-05 24.1 0.0 5.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EMR68070.1 - 0.00034 19.6 0.0 0.00073 18.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 EMR68070.1 - 0.025 14.4 2.2 0.2 11.5 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EMR68070.1 - 0.042 13.6 0.0 0.17 11.6 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain SRP54 PF00448.17 EMR68070.1 - 0.047 13.1 0.1 0.11 11.9 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 EMR68070.1 - 0.051 13.8 0.0 0.21 11.9 0.0 2.1 1 0 0 1 1 1 0 ABC transporter GYD PF08734.6 EMR68070.1 - 0.054 13.2 0.1 14 5.4 0.0 2.6 2 0 0 2 2 2 0 GYD domain FtsK_SpoIIIE PF01580.13 EMR68070.1 - 0.13 11.7 0.0 0.13 11.7 0.0 2.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EMR68070.1 - 0.2 11.9 0.0 0.2 11.9 0.0 3.0 2 1 0 2 2 1 0 AAA domain Glyco_hydro_18 PF00704.23 EMR68071.1 - 8.4e-19 68.2 5.1 1.6e-18 67.2 3.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chorismate_bind PF00425.13 EMR68072.1 - 1.6e-86 289.8 0.0 5.4e-86 288.0 0.0 1.8 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EMR68072.1 - 4.8e-30 104.4 0.0 2.4e-23 82.6 0.0 3.6 3 0 0 3 3 3 3 Anthranilate synthase component I, N terminal region GFA PF04828.9 EMR68073.1 - 0.00051 19.9 0.0 0.00065 19.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EMR68073.1 - 0.0042 16.2 0.9 0.0098 15.0 0.6 1.7 1 1 0 1 1 1 1 zinc-ribbon domain A2L_zn_ribbon PF08792.5 EMR68073.1 - 0.0061 15.9 0.6 0.015 14.7 0.1 1.8 1 1 1 2 2 2 1 A2L zinc ribbon domain zinc_ribbon_2 PF13240.1 EMR68073.1 - 0.0091 15.4 0.2 0.022 14.2 0.1 1.6 1 0 0 1 1 1 1 zinc-ribbon domain Yippee-Mis18 PF03226.9 EMR68073.1 - 0.061 13.3 0.1 0.096 12.7 0.1 1.5 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly NOB1_Zn_bind PF08772.6 EMR68073.1 - 0.086 12.6 0.5 0.15 11.8 0.4 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 EMR68073.1 - 0.1 12.0 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain ARD PF03079.9 EMR68074.1 - 7.1e-42 143.0 0.1 8.4e-42 142.7 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EMR68074.1 - 2e-09 36.8 0.0 3.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EMR68074.1 - 8.9e-06 25.4 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EMR68074.1 - 0.0056 16.1 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Cupin tRNA-synt_1c PF00749.16 EMR68075.1 - 6.7e-63 212.2 0.0 9.4e-63 211.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1b PF00579.20 EMR68076.1 - 1.8e-56 191.4 0.0 2e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF883 PF05957.8 EMR68076.1 - 0.079 13.3 1.6 0.16 12.4 0.5 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) GIDA PF01134.17 EMR68077.1 - 8.2e-155 515.4 0.0 1.2e-154 514.9 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Sec1 PF00995.18 EMR68077.1 - 2.9e-137 458.7 1.3 1.3e-135 453.2 0.9 2.1 1 1 0 1 1 1 1 Sec1 family GIDA_assoc_3 PF13932.1 EMR68077.1 - 2.3e-14 53.1 0.0 6.6e-14 51.7 0.0 1.9 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EMR68077.1 - 1.5e-05 24.9 0.1 2.9e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMR68077.1 - 5.6e-05 22.3 3.4 0.00011 21.4 2.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR68077.1 - 0.00098 18.0 2.8 0.0023 16.8 1.8 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EMR68077.1 - 0.0015 17.5 0.8 0.3 9.9 0.5 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EMR68077.1 - 0.051 13.1 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain B12-binding PF02310.14 EMR68077.1 - 0.055 13.3 0.2 0.055 13.3 0.1 2.4 3 0 0 3 3 2 0 B12 binding domain HI0933_like PF03486.9 EMR68077.1 - 0.062 11.7 1.3 0.31 9.4 0.4 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.1 EMR68077.1 - 0.067 13.4 0.1 0.25 11.6 0.1 2.0 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 EMR68077.1 - 0.071 13.1 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR68077.1 - 0.074 11.9 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EMR68077.1 - 0.1 13.0 0.3 0.46 10.9 0.2 2.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase JAB PF01398.16 EMR68078.1 - 1.1e-29 102.4 0.1 2.8e-29 101.1 0.1 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EMR68078.1 - 1.2e-06 28.0 0.0 2.7e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EMR68078.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Abi PF02517.11 EMR68079.1 - 1.7e-13 50.5 10.5 1.7e-13 50.5 7.3 3.0 1 1 1 2 2 2 1 CAAX protease self-immunity DUF1635 PF07795.6 EMR68079.1 - 0.078 12.3 0.3 1 8.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) MBOAT PF03062.14 EMR68080.1 - 1e-48 166.1 7.7 1e-48 166.1 5.4 2.2 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF4149 PF13664.1 EMR68080.1 - 0.048 13.7 0.3 0.048 13.7 0.2 3.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4149) adh_short PF00106.20 EMR68081.1 - 2.1e-19 70.0 0.0 2.8e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68081.1 - 1.9e-10 40.7 0.0 3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR68081.1 - 2e-08 33.9 0.0 4.3e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR68081.1 - 0.00039 19.2 0.0 0.00056 18.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMR68081.1 - 0.00041 20.4 0.0 0.00061 19.8 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EMR68081.1 - 0.0011 17.9 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EMR68081.1 - 0.015 14.5 0.0 0.035 13.3 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Peptidase_M24 PF00557.19 EMR68082.1 - 2.5e-40 138.2 0.0 3.5e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EMR68082.1 - 1.7e-22 80.3 0.0 1.4e-19 70.9 0.0 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain DUF2404 PF10296.4 EMR68083.1 - 5.9e-08 32.7 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Tn7_Tnp_TnsA_C PF08721.6 EMR68083.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 TnsA endonuclease C terminal UAA PF08449.6 EMR68084.1 - 2.7e-11 42.9 21.0 3.5e-11 42.5 14.6 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EMR68084.1 - 1.5e-08 34.4 8.6 1.5e-08 34.4 6.0 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EMR68084.1 - 0.0098 15.9 27.8 0.046 13.7 6.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family Peptidase_A24 PF01478.13 EMR68084.1 - 3.1 7.9 14.7 1.9 8.6 3.6 3.8 1 1 2 3 3 3 0 Type IV leader peptidase family Pyr_redox_2 PF07992.9 EMR68085.1 - 3.3e-21 76.0 0.0 7.1e-21 75.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR68085.1 - 2.9e-11 43.6 0.0 2e-10 40.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR68085.1 - 6.2e-07 29.6 0.0 0.00027 21.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR68085.1 - 0.014 14.2 0.1 0.37 9.5 0.0 2.3 1 1 1 2 2 2 0 FAD binding domain DER1 PF04511.10 EMR68086.1 - 6.7e-50 169.3 4.7 7.6e-50 169.1 3.2 1.0 1 0 0 1 1 1 1 Der1-like family Ribosomal_S10 PF00338.17 EMR68087.1 - 1.2e-23 82.7 0.0 2e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e FAM75 PF14650.1 EMR68087.1 - 0.057 12.8 0.6 0.084 12.2 0.4 1.4 1 1 0 1 1 1 0 FAM75 family Peptidase_M35 PF02102.10 EMR68088.1 - 3.2e-24 85.2 1.6 4e-24 84.9 1.1 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family DnaJ PF00226.26 EMR68089.1 - 2.1e-26 91.4 4.1 4e-26 90.5 2.8 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EMR68089.1 - 3.1e-21 75.0 0.0 4.8e-19 68.0 0.0 2.8 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EMR68089.1 - 2.5e-13 49.8 18.1 5.1e-13 48.8 12.6 1.5 1 0 0 1 1 1 1 DnaJ central domain NMDAR2_C PF10565.4 EMR68089.1 - 0.0048 15.6 0.1 0.0086 14.8 0.0 1.4 1 1 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus HypA PF01155.14 EMR68089.1 - 0.0096 15.5 5.9 0.3 10.7 0.7 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Val_tRNA-synt_C PF10458.4 EMR68089.1 - 0.038 14.0 1.7 0.074 13.1 1.2 1.4 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Cytochrom_c3_2 PF14537.1 EMR68089.1 - 0.076 13.3 6.4 0.16 12.3 4.4 1.5 1 0 0 1 1 1 0 Cytochrome c3 DUF1356 PF07092.7 EMR68089.1 - 0.14 11.2 2.4 0.6 9.2 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1356) Stc1 PF12898.2 EMR68089.1 - 1.1 9.3 12.7 3.3 7.8 2.3 2.3 1 1 1 2 2 2 0 Stc1 domain PIGA PF08288.7 EMR68090.1 - 1e-46 157.2 2.7 1.7e-46 156.4 0.4 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EMR68090.1 - 1.1e-29 103.0 0.0 1.7e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EMR68090.1 - 2.4e-15 56.7 0.4 4.5e-15 55.8 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EMR68090.1 - 2.2e-14 53.7 0.0 4.2e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMR68090.1 - 2.6e-14 53.6 0.0 5.7e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EMR68090.1 - 2.2e-05 24.3 0.5 3.5e-05 23.6 0.4 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EMR68090.1 - 0.00038 20.6 0.1 0.0011 19.1 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 hEGF PF12661.2 EMR68091.1 - 0.49 10.5 4.5 8.7 6.6 0.2 2.6 2 0 0 2 2 2 0 Human growth factor-like EGF DUF2267 PF10025.4 EMR68092.1 - 0.084 12.9 0.5 0.1 12.6 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) VWA_2 PF13519.1 EMR68093.1 - 5.3e-10 39.6 0.0 1.9e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF3584 PF12128.3 EMR68093.1 - 0.0057 14.0 23.6 0.0089 13.4 16.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) MitMem_reg PF13012.1 EMR68093.1 - 0.0073 16.3 3.1 0.0073 16.3 2.1 2.7 2 2 0 2 2 2 1 Maintenance of mitochondrial structure and function DUF4200 PF13863.1 EMR68093.1 - 0.017 15.1 14.2 0.017 15.1 9.8 3.5 2 1 2 4 4 3 0 Domain of unknown function (DUF4200) DUF2201 PF09967.4 EMR68093.1 - 0.048 13.6 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 VWA-like domain (DUF2201) APG6 PF04111.7 EMR68093.1 - 0.094 11.7 25.1 0.057 12.4 8.8 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Mnd1 PF03962.10 EMR68093.1 - 0.19 11.3 26.6 0.17 11.5 5.4 2.5 1 1 0 2 2 2 0 Mnd1 family Filament PF00038.16 EMR68093.1 - 0.21 11.0 26.2 0.93 8.9 10.7 2.1 1 1 1 2 2 2 0 Intermediate filament protein Tropomyosin PF00261.15 EMR68093.1 - 0.42 9.6 31.3 0.012 14.7 11.5 2.3 1 1 1 2 2 2 0 Tropomyosin Pox_A_type_inc PF04508.7 EMR68093.1 - 0.46 10.4 4.1 21 5.2 0.0 4.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Bacillus_HBL PF05791.6 EMR68093.1 - 0.5 9.7 13.4 0.33 10.2 1.5 2.8 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 EMR68093.1 - 1.5 7.9 10.8 1.6 7.8 4.3 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Lectin_N PF03954.9 EMR68093.1 - 1.9 7.9 9.3 0.86 9.0 0.7 2.7 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF763 PF05559.6 EMR68093.1 - 3.3 6.5 8.7 1.9 7.3 4.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF763) DUF1977 PF09320.6 EMR68093.1 - 3.6 7.8 7.0 6.1 7.1 4.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1977) TBPIP PF07106.8 EMR68093.1 - 4.3 6.8 26.4 0.62 9.6 2.8 3.1 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 EMR68093.1 - 4.6 6.9 30.8 0.13 12.0 3.6 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 EMR68093.1 - 7.4 6.9 21.4 0.69 10.2 2.6 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF972) DUF1996 PF09362.5 EMR68094.1 - 9e-90 300.4 0.5 1.2e-89 300.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Fructosamin_kin PF03881.9 EMR68095.1 - 0.016 14.1 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase GST_N_3 PF13417.1 EMR68096.1 - 1.4e-13 50.8 0.0 2.6e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR68096.1 - 2.6e-06 27.2 0.4 4.9e-06 26.3 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMR68096.1 - 0.00056 19.8 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR68096.1 - 0.0038 17.1 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR68096.1 - 0.03 14.7 0.0 0.044 14.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Helicase_C PF00271.26 EMR68097.1 - 4.2e-21 74.5 0.1 1.5e-20 72.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMR68097.1 - 1.3e-13 50.7 0.0 2.3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_5 PF07728.9 EMR68099.1 - 1.1e-10 41.3 0.0 2.2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMR68099.1 - 1.7e-10 41.0 0.0 3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EMR68099.1 - 2.4e-06 27.3 0.0 1e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EMR68099.1 - 5.6e-06 26.5 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMR68099.1 - 0.0079 16.2 0.0 0.094 12.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 EMR68099.1 - 0.017 14.2 0.0 2.1 7.4 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EMR68099.1 - 0.018 15.2 0.0 0.11 12.5 0.0 2.4 2 1 1 3 3 3 0 AAA domain Tyrosinase PF00264.15 EMR68100.1 - 2.6e-34 119.3 2.4 2.6e-34 119.3 1.7 1.7 1 1 1 2 2 2 1 Common central domain of tyrosinase RabGGT_insert PF07711.6 EMR68100.1 - 0.091 12.5 0.2 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Rab geranylgeranyl transferase alpha-subunit, insert domain adh_short PF00106.20 EMR68101.1 - 1.2e-19 70.8 2.0 1.6e-19 70.3 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68101.1 - 3e-09 36.7 1.9 4.8e-09 36.1 1.3 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR68101.1 - 4.3e-07 29.9 0.0 5.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMR68101.1 - 0.018 15.0 1.2 0.043 13.8 0.8 1.6 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EMR68101.1 - 0.02 14.3 0.1 0.029 13.8 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MtrD PF04207.7 EMR68101.1 - 0.15 11.3 1.4 0.48 9.7 0.3 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D adh_short PF00106.20 EMR68102.1 - 1.7e-16 60.5 0.1 2.4e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68102.1 - 4e-07 29.8 0.1 6.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR68102.1 - 2.8e-06 26.9 0.1 5.2e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR68102.1 - 0.00078 19.4 0.2 0.0018 18.3 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EMR68102.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Prp19 PF08606.6 EMR68102.1 - 0.0053 16.4 0.4 0.0089 15.7 0.3 1.3 1 0 0 1 1 1 1 Prp19/Pso4-like Shikimate_DH PF01488.15 EMR68102.1 - 0.0056 16.7 0.1 0.0093 16.0 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TIR-like PF10137.4 EMR68102.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain THF_DHG_CYH_C PF02882.14 EMR68102.1 - 0.029 13.4 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ecm29 PF13001.2 EMR68103.1 - 4.9e-65 219.9 0.1 2.4e-31 108.7 0.0 2.5 1 1 0 2 2 2 2 Proteasome stabiliser HEAT PF02985.17 EMR68103.1 - 3e-07 29.9 2.2 0.97 9.6 0.0 7.1 6 0 0 6 6 6 2 HEAT repeat Fungal_trans PF04082.13 EMR68104.1 - 0.00026 19.9 0.1 0.00036 19.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 EMR68106.1 - 1.3e-27 97.2 0.0 1.9e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR68106.1 - 7.2e-18 64.9 0.0 3.4e-17 62.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR68106.1 - 5.7e-09 35.8 0.0 8e-08 32.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EMR68106.1 - 0.0066 15.9 0.0 0.016 14.6 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EMR68106.1 - 0.068 12.3 0.3 0.92 8.6 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family Bac_rhamnosid PF05592.6 EMR68107.1 - 9.2e-49 166.0 1.5 1.9e-33 115.5 0.1 3.8 1 1 2 3 3 3 3 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EMR68107.1 - 1.8e-23 82.9 2.8 4.5e-19 68.6 0.0 3.4 2 1 1 3 3 3 2 Alpha-L-rhamnosidase N-terminal domain MFS_1 PF07690.11 EMR68108.1 - 3.2e-18 65.5 26.8 3.2e-18 65.5 18.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR68108.1 - 9.1e-09 34.0 5.8 1.3e-08 33.5 4.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Neurensin PF14927.1 EMR68108.1 - 2 7.7 4.2 4.1 6.7 0.0 3.2 5 0 0 5 5 5 0 Neurensin DUF4516 PF14990.1 EMR68108.1 - 2.1 7.9 8.3 8.2 6.0 1.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4516) SNF2_N PF00176.18 EMR68109.1 - 2.3e-54 184.2 1.1 3.9e-54 183.4 0.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMR68109.1 - 1.6e-14 53.5 0.1 5.6e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR68109.1 - 1.8e-09 37.6 0.0 4.4e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMR68109.1 - 4e-05 23.1 0.0 8.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.8 EMR68109.1 - 0.0023 17.6 6.3 0.0023 17.6 4.4 2.6 2 0 0 2 2 2 1 HSA 7TM_transglut PF14402.1 EMR68109.1 - 0.038 12.9 1.3 0.062 12.2 0.9 1.2 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase DEAD_2 PF06733.10 EMR68109.1 - 0.066 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 OMP_b-brl PF13505.1 EMR68110.1 - 0.15 12.0 2.0 0.26 11.2 1.4 1.4 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain NDUF_B8 PF05821.6 EMR68111.1 - 1.2e-06 28.2 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Cupin_2 PF07883.6 EMR68113.1 - 1.9e-09 36.9 0.0 2.8e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain CDO_I PF05995.7 EMR68113.1 - 0.0055 15.8 0.0 0.0064 15.6 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF4437 PF14499.1 EMR68113.1 - 0.032 13.1 0.0 0.043 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) FAD_binding_3 PF01494.14 EMR68114.1 - 3.6e-20 72.3 0.1 6e-20 71.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR68114.1 - 2.8e-08 33.0 0.3 0.0012 17.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase GST_N_3 PF13417.1 EMR68114.1 - 8.4e-05 22.7 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Pyr_redox PF00070.22 EMR68114.1 - 0.00038 20.7 0.1 0.0018 18.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GST_N_2 PF13409.1 EMR68114.1 - 0.0024 17.8 0.1 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NAD_binding_8 PF13450.1 EMR68114.1 - 0.0081 16.1 1.2 0.018 15.0 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 EMR68114.1 - 0.013 14.9 0.1 0.025 14.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GST_C_2 PF13410.1 EMR68114.1 - 0.097 12.5 0.0 0.31 10.9 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pyr_redox_2 PF07992.9 EMR68114.1 - 0.15 11.9 0.7 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase YchF-GTPase_C PF06071.8 EMR68115.1 - 6.9e-32 109.0 0.1 1.8e-31 107.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EMR68115.1 - 5.8e-17 61.7 0.0 1e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMR68115.1 - 9.9e-08 31.4 0.0 1.7e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Thioredoxin_7 PF13899.1 EMR68116.1 - 2.9e-13 49.6 0.0 9.3e-13 48.0 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like UBA_4 PF14555.1 EMR68116.1 - 2.1e-11 43.1 0.0 4.1e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EMR68116.1 - 8.8e-06 25.6 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.10 EMR68116.1 - 0.002 17.8 0.1 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Daxx PF03344.10 EMR68116.1 - 2 6.8 6.1 2.9 6.2 4.2 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EMR68116.1 - 3.1 5.7 5.2 4.1 5.3 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DnaJ PF00226.26 EMR68118.1 - 2.4e-09 36.7 0.8 2.4e-09 36.7 0.6 2.1 2 1 0 2 2 2 1 DnaJ domain MIP PF00230.15 EMR68119.1 - 3.9e-31 108.2 2.6 5e-31 107.9 1.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein Trypan_PARP PF05887.6 EMR68119.1 - 3 7.6 6.2 4.9 6.9 4.3 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4360 PF14273.1 EMR68120.1 - 4.1e-14 52.6 0.0 5.1e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RRM_1 PF00076.17 EMR68121.1 - 2.7e-45 151.8 0.0 7.2e-16 57.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR68121.1 - 3.8e-26 90.8 0.0 6.7e-09 35.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR68121.1 - 7.1e-23 80.2 0.0 2.4e-07 30.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMR68121.1 - 1.1e-06 28.4 0.0 0.00018 21.3 0.0 2.9 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EMR68121.1 - 6.4e-06 25.8 0.0 0.0031 17.2 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Syntaxin-6_N PF09177.6 EMR68122.1 - 0.0016 18.7 0.1 0.03 14.7 0.0 2.6 3 0 0 3 3 3 1 Syntaxin 6, N-terminal Glyco_hydro_42 PF02449.10 EMR68123.1 - 7.3e-08 31.9 0.0 3.8e-06 26.2 0.0 2.5 2 1 0 2 2 2 2 Beta-galactosidase Glyco_hydro_35 PF01301.14 EMR68123.1 - 0.00035 20.0 0.0 0.38 10.0 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 35 BNR_2 PF13088.1 EMR68124.1 - 5.6e-07 29.1 0.4 0.0001 21.7 0.3 2.5 1 1 0 1 1 1 1 BNR repeat-like domain DUF4185 PF13810.1 EMR68124.1 - 0.0046 15.9 0.6 2.8 6.7 0.1 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4185) BNR PF02012.15 EMR68124.1 - 0.0068 16.0 13.3 0.14 12.0 2.2 3.8 3 0 0 3 3 3 2 BNR/Asp-box repeat Ribonuc_L-PSP PF01042.16 EMR68125.1 - 4.4e-06 26.4 0.0 9.3e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 Endoribonuclease L-PSP Cytochrom_C_asm PF01578.15 EMR68126.1 - 0.00013 21.5 0.7 0.00019 21.0 0.5 1.1 1 0 0 1 1 1 1 Cytochrome C assembly protein DUF2427 PF10348.4 EMR68126.1 - 0.0038 16.7 5.2 0.0082 15.7 3.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) MFS_1 PF07690.11 EMR68126.1 - 0.015 14.0 5.1 0.021 13.5 3.6 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily CTP_transf_1 PF01148.15 EMR68126.1 - 0.018 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase family CDC45 PF02724.9 EMR68126.1 - 0.027 12.5 0.0 0.027 12.5 0.0 1.4 2 0 0 2 2 2 0 CDC45-like protein Cytochrom_B561 PF03188.11 EMR68126.1 - 0.054 13.3 7.1 0.87 9.4 5.3 2.5 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 Cytochrom_B_N PF00033.14 EMR68126.1 - 0.14 11.5 11.1 10 5.4 8.0 2.4 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Wzy_C PF04932.10 EMR68126.1 - 0.59 9.8 4.8 12 5.6 0.0 2.4 1 1 1 2 2 2 0 O-Antigen ligase RseC_MucC PF04246.7 EMR68126.1 - 3.3 7.2 4.9 2.2 7.8 0.6 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Abhydrolase_6 PF12697.2 EMR68128.1 - 8.5e-21 74.8 0.3 1e-20 74.6 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR68128.1 - 8e-14 51.7 0.2 3.1e-13 49.8 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR68128.1 - 5.6e-07 29.4 0.1 1.3e-06 28.2 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EMR68128.1 - 0.0056 15.1 0.0 0.0073 14.8 0.0 1.4 1 1 0 1 1 1 1 Ndr family Dynamin_N PF00350.18 EMR68130.1 - 7.6e-14 51.8 3.9 7.7e-14 51.8 0.0 2.9 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EMR68130.1 - 1.8e-05 24.6 0.0 0.0006 19.7 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMR68130.1 - 0.00059 19.0 0.0 0.0087 15.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EMR68130.1 - 0.0012 19.1 1.6 0.002 18.4 0.0 2.2 2 1 0 2 2 2 1 ABC transporter Miro PF08477.8 EMR68130.1 - 0.0085 16.5 0.0 0.028 14.9 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 EMR68130.1 - 0.047 14.5 0.6 0.37 11.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EMR68130.1 - 0.085 13.0 2.1 1 9.5 0.0 3.8 5 1 0 6 6 5 0 AAA domain AAA_29 PF13555.1 EMR68130.1 - 0.093 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EMR68130.1 - 0.3 11.0 0.0 0.3 11.0 0.0 2.7 4 0 0 4 4 4 0 AAA ATPase domain AAA_23 PF13476.1 EMR68130.1 - 0.97 9.7 0.0 0.97 9.7 0.0 3.2 2 1 0 2 2 1 0 AAA domain DUF724 PF05266.9 EMR68130.1 - 2 8.0 10.2 6.8 6.2 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DivIC PF04977.10 EMR68130.1 - 6.1 6.3 7.7 7.4 6.1 0.2 3.1 3 0 0 3 3 3 0 Septum formation initiator zf-MYND PF01753.13 EMR68131.1 - 7.8e-08 32.0 9.0 1.6e-07 31.0 6.2 1.6 1 0 0 1 1 1 1 MYND finger adh_short PF00106.20 EMR68132.1 - 2.6e-24 86.0 1.6 6.1e-24 84.8 1.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68132.1 - 1.2e-07 31.5 0.4 0.00031 20.4 0.1 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EMR68132.1 - 4.2e-07 29.9 0.0 8.9e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR68132.1 - 5.9e-05 22.6 0.0 8.1e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMR68132.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain CorA PF01544.13 EMR68133.1 - 1e-07 31.2 0.4 1e-07 31.2 0.3 2.1 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF3591 PF12157.3 EMR68133.1 - 0.03 12.7 0.0 0.047 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) Glyco_hydro_61 PF03443.9 EMR68134.1 - 2e-67 227.2 0.2 3.2e-67 226.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Sugar_tr PF00083.19 EMR68135.1 - 6.5e-62 209.5 20.4 5.1e-41 140.6 3.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR68135.1 - 2.6e-12 46.1 35.8 1.6e-10 40.2 23.2 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Aconitase PF00330.15 EMR68136.1 - 3.4e-183 609.3 0.0 4e-183 609.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMR68136.1 - 2.9e-45 153.5 0.0 5.1e-45 152.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Abhydrolase_6 PF12697.2 EMR68137.1 - 5.9e-30 104.8 0.0 7.4e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR68137.1 - 2.1e-14 53.6 0.0 4.2e-14 52.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR68137.1 - 4.3e-08 33.0 0.0 4.7e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMR68137.1 - 0.0031 17.3 0.0 0.012 15.4 0.0 1.9 1 1 1 2 2 2 1 Putative lysophospholipase BTB PF00651.26 EMR68138.1 - 7e-07 29.2 0.3 2.5e-06 27.4 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain DSBA PF01323.15 EMR68139.1 - 3.1e-23 82.3 0.1 3.5e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EMR68139.1 - 0.0006 19.8 0.0 0.00071 19.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Cullin PF00888.17 EMR68140.1 - 3.2e-120 402.4 1.1 4e-120 402.1 0.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EMR68140.1 - 2.5e-24 84.9 0.4 6.3e-24 83.5 0.3 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Lipase_GDSL_2 PF13472.1 EMR68141.1 - 1.8e-12 47.7 0.4 3.1e-12 46.9 0.3 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMR68141.1 - 1.4e-07 31.6 0.1 4.8e-07 29.8 0.1 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EMR68141.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Laminin_G_3 PF13385.1 EMR68142.1 - 0.4 10.9 4.2 0.64 10.2 2.9 1.4 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily YbjQ_1 PF01906.12 EMR68144.1 - 2.1e-10 40.9 0.0 2.8e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Putative heavy-metal-binding zf-DNL PF05180.7 EMR68145.1 - 1.1e-26 92.3 0.1 1.8e-26 91.6 0.1 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 EMR68145.1 - 0.0023 17.3 0.2 0.005 16.3 0.2 1.5 1 0 0 1 1 1 1 CSL zinc finger NTPase_1 PF03266.10 EMR68145.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 NTPase SH3_1 PF00018.23 EMR68146.1 - 6.9e-09 34.9 0.0 1.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMR68146.1 - 2e-08 33.6 0.8 3e-08 33.0 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EMR68146.1 - 4.6e-05 22.8 0.0 0.0001 21.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Menin PF05053.8 EMR68146.1 - 0.17 10.0 1.0 0.33 9.0 0.7 1.4 1 0 0 1 1 1 0 Menin FAD-oxidase_C PF02913.14 EMR68147.1 - 2.7e-12 46.5 0.1 3.2e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Cyclin_C PF02984.14 EMR68149.1 - 0.095 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain Ssu72 PF04722.8 EMR68150.1 - 7.3e-85 283.2 0.0 8.5e-85 283.0 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Metallophos PF00149.23 EMR68151.1 - 4.9e-08 32.6 5.5 1.8e-07 30.7 3.8 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CDC45 PF02724.9 EMR68151.1 - 0.99 7.3 4.5 1.4 6.8 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1843 PF08898.5 EMR68152.1 - 0.017 15.1 0.3 0.017 15.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) bZIP_1 PF00170.16 EMR68152.1 - 0.02 14.8 0.1 0.02 14.8 0.0 4.2 4 0 0 4 4 4 0 bZIP transcription factor Fib_alpha PF08702.5 EMR68152.1 - 0.65 10.1 22.0 4.9 7.2 1.0 3.9 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family CytochromB561_N PF09786.4 EMR68152.1 - 3.7 5.8 7.7 1.7 6.9 2.1 2.4 2 0 0 2 2 2 0 Cytochrome B561, N terminal SlyX PF04102.7 EMR68152.1 - 3.8 7.9 27.9 2.1 8.7 0.6 6.2 5 2 1 6 6 6 0 SlyX Pro_dh PF01619.13 EMR68153.1 - 2.7e-33 115.3 0.0 1.7e-23 83.0 0.0 2.6 2 1 0 2 2 2 2 Proline dehydrogenase Sugar_tr PF00083.19 EMR68154.1 - 1.7e-113 379.6 25.0 1.9e-113 379.4 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR68154.1 - 7.9e-22 77.4 28.3 2.3e-14 52.8 4.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily CGI-121 PF08617.5 EMR68155.1 - 2.2e-49 167.2 0.3 2.5e-49 167.0 0.2 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Stork_head PF10264.4 EMR68155.1 - 0.094 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain Cytokin_check_N PF10407.4 EMR68156.1 - 0.033 13.8 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus Rad60-SLD PF11976.3 EMR68156.1 - 0.11 12.2 0.0 7.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Fungal_trans PF04082.13 EMR68157.1 - 1.5e-18 66.6 0.7 2.3e-18 65.9 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR68157.1 - 0.00011 22.0 0.7 0.00028 20.7 0.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EMR68158.1 - 3.9e-16 58.9 0.0 2e-15 56.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR68158.1 - 1e-07 31.3 0.0 4.8e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EMR68158.1 - 0.0014 18.4 0.0 0.018 14.7 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EMR68158.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.9 EMR68158.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec61_beta PF03911.11 EMR68159.1 - 1.5e-20 72.6 1.4 2e-20 72.2 1.0 1.2 1 0 0 1 1 1 1 Sec61beta family DUF1180 PF06679.7 EMR68159.1 - 0.087 12.7 1.9 0.11 12.4 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) adh_short PF00106.20 EMR68160.1 - 2.9e-16 59.8 0.6 1.2e-15 57.8 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68160.1 - 1.5e-08 34.5 0.1 2.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR68160.1 - 0.0044 16.8 0.0 0.0059 16.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EMR68160.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAPRTase PF04095.11 EMR68161.1 - 3.7e-49 167.2 0.0 1e-48 165.8 0.0 1.6 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family p450 PF00067.17 EMR68162.1 - 1.8e-41 142.1 0.0 2.2e-29 102.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 KH_1 PF00013.24 EMR68164.1 - 2.9e-12 46.0 0.0 4.3e-09 35.8 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EMR68164.1 - 8.6e-08 31.6 1.0 1.3e-05 24.6 0.0 3.2 3 0 0 3 3 3 2 KH domain tRNA-synt_2d PF01409.15 EMR68165.1 - 5.8e-84 281.1 0.0 1.2e-83 280.1 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EMR68165.1 - 3.5e-05 22.7 2.8 0.00024 20.0 0.0 3.0 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EMR68165.1 - 0.0016 18.0 0.1 0.0048 16.4 0.0 2.0 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF3712 PF12505.3 EMR68166.1 - 1.1e-08 35.1 0.3 1.8e-07 31.1 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EMR68166.1 - 8.2e-06 26.1 0.5 9.4 6.6 0.0 5.2 5 0 0 5 5 5 3 Late embryogenesis abundant protein adh_short PF00106.20 EMR68167.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase OTCace_N PF02729.16 EMR68168.1 - 1.2e-44 151.3 0.1 1.7e-44 150.9 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EMR68168.1 - 1.3e-37 129.0 0.0 2.9e-37 127.9 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ALS_ss_C PF10369.4 EMR68169.1 - 1.6e-18 66.1 0.0 6.1e-17 61.1 0.0 2.5 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.20 EMR68169.1 - 3.2e-13 48.8 0.1 6.3e-13 47.9 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EMR68169.1 - 8.3e-10 38.3 0.0 1.7e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 ACT domain Pkinase PF00069.20 EMR68170.1 - 0.006 15.7 0.0 0.21 10.6 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR68170.1 - 0.11 11.6 0.0 1.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein tyrosine kinase Arginase PF00491.16 EMR68171.1 - 7.2e-75 251.8 0.7 8.5e-75 251.6 0.5 1.0 1 0 0 1 1 1 1 Arginase family FAD_binding_4 PF01565.18 EMR68172.1 - 5.7e-22 77.6 0.9 1.4e-21 76.4 0.6 1.7 1 0 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.13 EMR68172.1 - 3.9e-07 29.2 0.0 8.6e-07 28.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR68172.1 - 7.3e-07 29.0 12.2 1.4e-06 28.1 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mating_N PF12731.2 EMR68172.1 - 0.028 14.2 0.4 2.9 7.8 0.1 3.1 3 0 0 3 3 3 0 Mating-type protein beta 1 Anth_Ig PF05587.8 EMR68175.1 - 0.04 13.7 0.2 0.053 13.3 0.2 1.3 1 1 0 1 1 1 0 Anthrax receptor extracellular domain ECF-ribofla_trS PF07155.7 EMR68175.1 - 0.056 13.1 0.0 0.062 13.0 0.0 1.0 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component Abhydrolase_6 PF12697.2 EMR68176.1 - 7.1e-11 42.4 0.3 8.6e-11 42.1 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR68176.1 - 3.4e-07 30.1 0.6 5.4e-07 29.4 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 EMR68176.1 - 3.8e-07 29.6 0.0 7.6e-07 28.6 0.0 1.4 2 0 0 2 2 2 1 Lipase (class 2) DUF676 PF05057.9 EMR68176.1 - 0.00082 18.7 0.0 0.0018 17.6 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EMR68176.1 - 0.0035 16.9 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EMR68176.1 - 0.0067 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 EMR68176.1 - 0.042 12.9 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2974 PF11187.3 EMR68176.1 - 0.062 12.6 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Smg4_UPF3 PF03467.10 EMR68177.1 - 4.7e-08 33.2 0.0 6.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Smg-4/UPF3 family FRG2 PF15315.1 EMR68177.1 - 0.14 12.1 0.2 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 DUF3331 PF11811.3 EMR68178.1 - 0.0084 15.6 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3331) Peptidase_M64 PF09471.5 EMR68179.1 - 0.063 12.9 0.3 0.092 12.3 0.2 1.2 1 0 0 1 1 1 0 IgA Peptidase M64 DUF1025 PF06262.6 EMR68179.1 - 0.14 11.9 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase GDPD PF03009.12 EMR68180.1 - 6.6e-35 120.8 0.0 7.6e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ras PF00071.17 EMR68181.1 - 1.2e-47 161.2 0.0 1.6e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR68181.1 - 1.2e-12 48.3 0.0 1.9e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMR68181.1 - 4.9e-06 25.8 0.0 1.7e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMR68181.1 - 0.035 13.3 0.0 0.095 11.9 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EMR68181.1 - 0.087 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Metallophos PF00149.23 EMR68182.1 - 2.2e-38 131.6 0.0 2.3e-37 128.3 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SBP56 PF05694.6 EMR68184.1 - 0.00016 20.3 0.0 0.0021 16.6 0.0 2.4 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 EMR68184.1 - 0.002 17.3 0.1 0.19 10.7 0.2 2.6 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 EMR68184.1 - 0.012 15.0 0.0 0.73 9.1 0.0 2.8 3 0 0 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region DUF1513 PF07433.6 EMR68184.1 - 0.21 10.4 0.1 20 3.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) GRP PF07172.6 EMR68185.1 - 0.0015 18.9 10.4 0.003 17.9 7.2 1.4 1 0 0 1 1 1 1 Glycine rich protein family Pkinase PF00069.20 EMR68186.1 - 3.9e-08 32.7 0.0 0.00015 21.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR68186.1 - 0.00042 19.4 0.0 0.04 12.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase adh_short PF00106.20 EMR68187.1 - 1.8e-13 50.7 0.2 2.8e-13 50.1 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68187.1 - 3.2e-05 23.6 1.0 4.7e-05 23.1 0.7 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR68187.1 - 3.9e-05 23.7 0.2 5.4e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR68187.1 - 0.014 14.8 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Smg4_UPF3 PF03467.10 EMR68189.1 - 7e-17 61.9 1.3 7e-17 61.9 0.9 3.3 4 0 0 4 4 4 1 Smg-4/UPF3 family RRM_1 PF00076.17 EMR68189.1 - 1.7e-05 24.3 0.2 0.00017 21.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR68189.1 - 0.0016 18.3 0.0 0.0041 17.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR68189.1 - 0.0054 16.5 0.0 0.029 14.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Skp1_POZ PF03931.10 EMR68190.1 - 8.1e-12 45.0 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain TRF PF08558.5 EMR68191.1 - 4.9e-41 140.6 0.1 8.2e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Aldedh PF00171.17 EMR68192.1 - 1.3e-186 620.4 0.0 1.5e-186 620.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMR68192.1 - 0.019 13.6 0.0 0.032 12.9 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) MFS_1 PF07690.11 EMR68193.1 - 6.3e-26 90.9 19.0 2.6e-25 88.9 13.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF972 PF06156.8 EMR68194.1 - 0.0031 17.8 5.9 0.32 11.3 0.3 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF972) APG6 PF04111.7 EMR68194.1 - 0.0093 15.0 9.5 0.42 9.6 6.6 2.0 1 1 0 1 1 1 1 Autophagy protein Apg6 Translin PF01997.11 EMR68194.1 - 0.075 12.6 0.3 0.075 12.6 0.2 1.8 2 1 0 2 2 2 0 Translin family DUF523 PF04463.7 EMR68194.1 - 0.08 12.6 0.3 0.52 10.0 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF523) Bacillus_HBL PF05791.6 EMR68194.1 - 0.084 12.2 4.0 5.9 6.2 1.7 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Lebercilin PF15619.1 EMR68194.1 - 0.086 12.2 11.2 0.072 12.5 5.6 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Atg14 PF10186.4 EMR68194.1 - 0.11 11.3 9.1 0.12 11.3 5.8 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Cep57_MT_bd PF06657.8 EMR68194.1 - 0.12 12.3 6.7 2.6 8.0 1.1 3.0 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DivIVA PF05103.8 EMR68194.1 - 0.12 12.4 12.1 0.27 11.3 6.2 2.7 1 1 1 2 2 2 0 DivIVA protein PLAC9 PF15205.1 EMR68194.1 - 0.14 12.4 0.3 0.52 10.6 0.0 1.9 2 0 0 2 2 2 0 Placenta-specific protein 9 bZIP_1 PF00170.16 EMR68194.1 - 0.15 12.0 10.2 9.1 6.3 0.5 4.5 3 2 1 4 4 4 0 bZIP transcription factor Rootletin PF15035.1 EMR68194.1 - 0.16 11.9 10.6 0.86 9.5 4.8 2.7 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion BLOC1_2 PF10046.4 EMR68194.1 - 0.18 11.9 9.5 7.9 6.6 1.1 3.2 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4201 PF13870.1 EMR68194.1 - 0.18 11.2 13.6 1.9 7.8 5.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Spc7 PF08317.6 EMR68194.1 - 0.19 10.3 8.6 0.19 10.3 4.8 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein EzrA PF06160.7 EMR68194.1 - 0.2 9.8 9.2 0.23 9.5 6.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.3 EMR68194.1 - 0.2 11.3 5.7 0.83 9.3 1.0 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 EMR68194.1 - 0.21 11.0 12.3 0.76 9.3 0.6 3.4 1 1 2 3 3 3 0 Septum formation initiator DUF445 PF04286.7 EMR68194.1 - 0.22 11.0 5.9 2.4 7.6 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) CCDC155 PF14662.1 EMR68194.1 - 0.23 11.0 7.2 0.77 9.3 4.7 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Cauli_AT PF03233.8 EMR68194.1 - 0.25 11.0 2.9 0.28 10.8 0.7 1.9 1 1 1 2 2 2 0 Aphid transmission protein DUF4200 PF13863.1 EMR68194.1 - 0.33 10.8 13.5 2.5 8.0 6.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4618 PF15397.1 EMR68194.1 - 0.38 10.0 7.5 2.3 7.5 0.4 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Laminin_II PF06009.7 EMR68194.1 - 0.4 10.4 5.5 11 5.7 0.0 2.8 1 1 1 2 2 2 0 Laminin Domain II IncA PF04156.9 EMR68194.1 - 0.51 9.9 7.9 4 7.0 5.6 2.2 1 1 0 1 1 1 0 IncA protein DUF4515 PF14988.1 EMR68194.1 - 0.53 9.9 11.5 0.21 11.2 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) DUF904 PF06005.7 EMR68194.1 - 0.58 10.4 7.4 40 4.5 4.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 EMR68194.1 - 1.2 8.9 12.9 1.5 8.6 0.5 4.1 4 1 0 4 4 3 0 Basic region leucine zipper DUF948 PF06103.6 EMR68194.1 - 1.2 8.9 3.5 10 6.0 0.1 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.2 EMR68194.1 - 1.9 8.3 11.9 40 4.0 8.2 2.6 1 1 0 1 1 1 0 Tropomyosin like Fib_alpha PF08702.5 EMR68194.1 - 2 8.5 9.2 12 6.0 5.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 EMR68194.1 - 2.6 7.9 8.3 3.2 7.5 3.8 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4315 PF14193.1 EMR68194.1 - 3.5 7.6 7.0 5.8 6.9 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4315) CCDC-167 PF15188.1 EMR68194.1 - 3.7 7.5 6.5 29 4.6 0.2 3.2 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 AAA_23 PF13476.1 EMR68194.1 - 3.8 7.8 6.6 5.1 7.3 4.6 1.3 1 1 0 1 1 1 0 AAA domain Mto2_bdg PF12808.2 EMR68194.1 - 3.9 7.6 7.9 4.4 7.4 0.8 3.3 2 2 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TPR_MLP1_2 PF07926.7 EMR68194.1 - 4.3 7.0 12.0 7.1 6.3 5.4 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2570 PF10828.3 EMR68194.1 - 4.7 6.8 5.9 3.3 7.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) UPF0242 PF06785.6 EMR68194.1 - 5 5.6 8.5 1.2 7.7 0.8 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) TMF_DNA_bd PF12329.3 EMR68194.1 - 5.2 6.9 9.8 1.1 9.0 0.4 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 EMR68194.1 - 5.6 6.5 9.8 1.2 8.7 1.8 2.1 1 1 1 2 2 2 0 Mnd1 family Uds1 PF15456.1 EMR68194.1 - 9.4 6.2 11.7 58 3.6 1.0 2.3 1 1 1 2 2 2 0 Up-regulated During Septation DASH_Dad1 PF08649.5 EMR68196.1 - 4.9e-25 86.9 0.8 6.7e-25 86.5 0.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 WVELL PF14043.1 EMR68196.1 - 0.11 12.1 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 WVELL protein Cupin_1 PF00190.17 EMR68197.1 - 1.2e-28 99.3 0.0 1e-14 54.1 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EMR68197.1 - 7.9e-22 76.5 0.9 5e-12 45.1 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EMR68197.1 - 1.3e-08 34.0 0.0 0.0012 18.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EMR68197.1 - 1.7e-05 24.5 1.3 0.1 12.2 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 EMR68197.1 - 0.0051 16.4 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 2 Cupin Pyridox_oxidase PF01243.15 EMR68198.1 - 3.3e-05 23.8 0.0 7.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase C2 PF00168.25 EMR68199.1 - 1.1e-13 50.8 0.0 9.5e-12 44.6 0.0 2.4 2 0 0 2 2 2 2 C2 domain DUF2404 PF10296.4 EMR68199.1 - 0.058 13.5 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) DUF2353 PF09789.4 EMR68200.1 - 0.0014 17.9 2.7 0.002 17.4 1.9 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) AAA_27 PF13514.1 EMR68200.1 - 0.12 10.0 10.4 0.15 9.7 7.2 1.0 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EMR68200.1 - 0.75 9.3 6.3 0.25 10.8 1.8 1.7 1 1 1 2 2 2 0 IncA protein ADIP PF11559.3 EMR68200.1 - 0.78 9.6 10.1 3.5 7.4 0.4 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.1 EMR68200.1 - 1.4 7.7 9.6 4.8 6.0 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.15 EMR68200.1 - 1.8 8.3 5.2 5.6 6.7 0.7 2.2 2 0 0 2 2 2 0 Prefoldin subunit DivIC PF04977.10 EMR68200.1 - 4 6.9 7.0 2.6 7.6 1.4 2.4 2 1 0 2 2 2 0 Septum formation initiator zf-C3HC4_2 PF13923.1 EMR68201.1 - 3.2e-06 27.0 8.7 5.1e-06 26.4 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMR68201.1 - 4.2e-06 26.4 12.9 6.9e-06 25.7 8.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMR68201.1 - 6.6e-06 25.6 7.7 1e-05 25.0 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMR68201.1 - 3e-05 23.6 9.9 4.3e-05 23.0 6.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMR68201.1 - 0.002 18.1 9.5 0.0058 16.7 6.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger DnaJ PF00226.26 EMR68203.1 - 0.002 17.8 0.0 0.0062 16.2 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Trypan_PARP PF05887.6 EMR68203.1 - 0.0068 16.2 6.4 0.0068 16.2 4.5 2.1 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) OmpH PF03938.9 EMR68203.1 - 0.61 10.0 7.0 0.96 9.3 4.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) U79_P34 PF03064.11 EMR68203.1 - 0.66 9.4 11.6 0.97 8.9 8.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2346 PF09803.4 EMR68203.1 - 6.1 6.7 10.5 0.74 9.7 4.0 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2346) adh_short PF00106.20 EMR68204.1 - 5.8e-08 32.8 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR68204.1 - 0.077 12.7 0.1 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR68205.1 - 1.6e-15 57.3 0.1 3.5e-15 56.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR68205.1 - 2.4e-07 30.6 0.0 3.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR68205.1 - 0.0025 17.8 0.1 0.03 14.3 0.1 2.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EMR68205.1 - 0.0028 17.4 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Mito_fiss_reg PF05308.6 EMR68206.1 - 3.1 7.1 20.1 0.022 14.1 4.0 3.0 3 0 0 3 3 3 0 Mitochondrial fission regulator Peptidase_M20 PF01546.23 EMR68207.1 - 3.1e-22 79.0 0.1 4.4e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMR68207.1 - 4.4e-18 65.0 0.0 7.3e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMR68207.1 - 0.01 15.6 0.0 0.37 10.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase family M28 Haemolytic PF01809.13 EMR68208.1 - 0.39 10.3 3.9 2.8 7.6 0.1 2.4 1 1 1 2 2 2 0 Haemolytic domain NAD_binding_4 PF07993.7 EMR68210.1 - 1.2e-07 30.9 0.0 1.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EMR68210.1 - 1.9e-06 28.0 0.0 4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EMR68210.1 - 0.014 15.2 0.1 0.057 13.3 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EMR68210.1 - 0.086 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 EMR68211.1 - 1.1e-16 60.5 13.1 1.6e-16 59.9 9.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Flavin_Reduct PF01613.13 EMR68212.1 - 1.5e-12 47.5 0.0 2.2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 EMR68212.1 - 0.00026 20.6 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF447) Abhydrolase_1 PF00561.15 EMR68213.1 - 1.9e-10 40.6 0.0 3.4e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR68213.1 - 0.005 16.7 0.1 0.0073 16.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR68213.1 - 0.02 14.6 0.1 0.045 13.5 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family GATase_4 PF13230.1 EMR68214.1 - 7.2e-16 57.6 0.0 2.8e-14 52.4 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMR68214.1 - 3.5e-09 36.7 0.0 7.1e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EMR68214.1 - 7e-05 21.7 0.0 0.0002 20.2 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferases class-II RTA1 PF04479.8 EMR68215.1 - 2.4e-27 95.8 7.2 3.1e-27 95.5 5.0 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF373 PF04123.8 EMR68215.1 - 0.53 9.2 3.9 0.68 8.8 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Cation_efflux PF01545.16 EMR68216.1 - 1.3e-30 106.4 5.0 1.6e-30 106.1 3.5 1.1 1 0 0 1 1 1 1 Cation efflux family Paf1 PF03985.8 EMR68219.1 - 6.5e-54 183.3 0.0 1.8e-53 181.8 0.0 1.6 1 1 0 1 1 1 1 Paf1 Rer1 PF03248.8 EMR68220.1 - 8.7e-81 269.7 2.5 9.8e-81 269.5 1.7 1.0 1 0 0 1 1 1 1 Rer1 family Aldo_ket_red PF00248.16 EMR68222.1 - 5.5e-57 192.7 0.0 6.2e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Big_1 PF02369.11 EMR68223.1 - 0.00028 20.7 0.9 0.00059 19.7 0.6 1.6 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) SWM_repeat PF13753.1 EMR68223.1 - 0.0012 17.9 1.6 0.0015 17.6 1.1 1.2 1 0 0 1 1 1 1 Putative flagellar system-associated repeat DUF824 PF05688.6 EMR68223.1 - 0.014 14.9 0.1 0.037 13.6 0.1 1.7 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) Tom5 PF10642.4 EMR68223.1 - 0.099 12.2 0.5 0.21 11.2 0.3 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase CarboxypepD_reg PF13620.1 EMR68223.1 - 0.47 10.5 2.4 10 6.2 0.1 3.1 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain DAHP_synth_1 PF00793.15 EMR68225.1 - 4.3e-101 337.1 0.1 5.1e-101 336.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ribosomal_L50 PF10501.4 EMR68226.1 - 1e-15 57.6 0.6 1.5e-15 57.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal subunit 39S DUF566 PF04484.7 EMR68228.1 - 0.15 11.5 5.8 0.18 11.2 4.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) SGL PF08450.7 EMR68229.1 - 0.008 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Acyl-CoA_dh_1 PF00441.19 EMR68230.1 - 7.1e-29 100.8 1.9 7.7e-29 100.7 1.3 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EMR68230.1 - 2.2e-12 47.3 0.9 2.5e-12 47.1 0.6 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AAA PF00004.24 EMR68231.1 - 5.7e-25 88.0 2.4 2.1e-13 50.6 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR68231.1 - 7.5e-10 39.0 2.1 0.024 14.7 0.0 4.5 2 2 0 2 2 2 2 AAA domain AAA_11 PF13086.1 EMR68231.1 - 4.4e-08 32.9 11.8 1.2e-06 28.3 5.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.1 EMR68231.1 - 7.1e-08 32.0 0.4 0.011 15.4 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_5 PF07728.9 EMR68231.1 - 2.4e-07 30.5 0.4 0.04 13.6 0.1 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EMR68231.1 - 2.8e-05 23.3 0.2 0.28 10.3 0.0 3.0 2 2 2 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EMR68231.1 - 0.00017 21.2 0.6 0.64 9.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EMR68231.1 - 0.00023 20.6 0.1 0.29 10.5 0.0 2.9 2 1 0 2 2 2 2 IstB-like ATP binding protein Torsin PF06309.6 EMR68231.1 - 0.00023 21.0 0.1 3.3 7.6 0.0 3.4 2 1 0 3 3 3 2 Torsin RNA_helicase PF00910.17 EMR68231.1 - 0.00042 20.4 0.1 1.8 8.7 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_17 PF13207.1 EMR68231.1 - 0.0033 18.2 22.8 0.017 15.8 0.1 3.8 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EMR68231.1 - 0.008 15.2 9.9 0.07 12.1 0.0 4.0 4 2 0 4 4 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 EMR68231.1 - 0.036 13.5 6.8 13 5.1 0.0 3.6 2 2 1 4 4 4 0 AAA-like domain AAA_16 PF13191.1 EMR68231.1 - 0.11 12.4 6.6 2.2 8.2 0.0 3.1 3 0 0 3 3 2 0 AAA ATPase domain AAA_25 PF13481.1 EMR68231.1 - 0.13 11.6 0.7 15 4.8 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EMR68231.1 - 0.14 12.0 0.0 0.14 12.0 0.0 3.3 3 1 0 3 3 2 0 AAA domain AAA_18 PF13238.1 EMR68231.1 - 0.22 11.8 0.1 0.22 11.8 0.0 4.3 3 1 0 3 3 2 0 AAA domain AAA_28 PF13521.1 EMR68231.1 - 0.39 10.6 0.0 0.39 10.6 0.0 4.3 3 1 1 4 4 3 0 AAA domain SprA-related PF12118.3 EMR68231.1 - 0.91 8.7 26.5 1.6 7.9 18.3 1.3 1 0 0 1 1 1 0 SprA-related family SOBP PF15279.1 EMR68231.1 - 6 7.1 10.8 10 6.4 7.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Parvo_coat PF00740.13 EMR68231.1 - 6.5 5.5 10.2 11 4.8 7.0 1.3 1 0 0 1 1 1 0 Parvovirus coat protein VP2 SMP PF04927.7 EMR68233.1 - 5.8e-12 45.3 13.1 1.7e-09 37.4 2.5 2.1 1 1 1 2 2 2 2 Seed maturation protein NAD_binding_4 PF07993.7 EMR68234.1 - 2.7e-25 88.7 0.0 4.2e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EMR68234.1 - 1.3e-24 86.3 0.1 4.1e-24 84.7 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EMR68234.1 - 2.7e-10 40.0 0.0 4.6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1389 PF07146.6 EMR68234.1 - 0.28 10.1 0.0 0.47 9.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) PAT1 PF09770.4 EMR68236.1 - 0.46 8.6 25.8 0.58 8.3 17.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EI24 PF07264.6 EMR68237.1 - 1.3e-06 27.9 6.3 3.4e-06 26.6 4.4 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Dicistro_VP4 PF11492.3 EMR68237.1 - 0.037 14.0 0.1 0.48 10.4 0.0 2.7 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 DUF2007 PF09413.5 EMR68237.1 - 0.17 11.7 0.3 0.34 10.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) ADH_zinc_N PF00107.21 EMR68240.1 - 8.3e-10 38.3 0.0 1.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR68240.1 - 2.6e-09 38.0 0.0 5.9e-09 36.8 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR68240.1 - 3.9e-07 29.7 0.0 9.4e-07 28.5 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2781 PF10914.3 EMR68242.1 - 5.2e-29 100.9 7.5 6.3e-29 100.6 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Peptidase_S9 PF00326.16 EMR68242.1 - 0.041 13.1 0.2 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family MFS_1 PF07690.11 EMR68243.1 - 3.5e-30 104.9 25.1 3.5e-30 104.9 17.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily GMC_oxred_N PF00732.14 EMR68244.1 - 1.4e-61 208.2 0.0 1.8e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR68244.1 - 1.4e-33 116.2 0.0 1.1e-32 113.3 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EMR68244.1 - 4e-06 26.7 0.1 2.1e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR68244.1 - 1.2e-05 24.3 0.1 0.00061 18.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMR68244.1 - 0.00046 19.2 0.1 0.001 18.0 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EMR68244.1 - 0.00083 18.3 0.0 0.02 13.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EMR68244.1 - 0.0052 15.3 0.0 0.01 14.3 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EMR68244.1 - 0.0079 15.3 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EMR68244.1 - 0.018 15.1 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR68244.1 - 0.047 13.5 0.0 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR68244.1 - 0.086 12.6 0.5 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF4387 PF14330.1 EMR68246.1 - 2.6e-23 82.1 0.0 5.1e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 EMR68246.1 - 2.7e-13 49.1 0.0 1.6e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) adh_short PF00106.20 EMR68247.1 - 2.2e-26 92.7 0.1 3.5e-26 92.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68247.1 - 3.1e-08 33.5 1.0 4.6e-07 29.6 0.7 2.2 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR68247.1 - 8.8e-07 28.9 0.0 1.3e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 EMR68247.1 - 1.1e-06 27.5 0.1 2.6e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EMR68247.1 - 2.3e-05 23.5 0.1 4.1e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EMR68247.1 - 0.00045 19.7 0.1 0.00086 18.8 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EMR68247.1 - 0.0019 18.2 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 EMR68247.1 - 0.0028 17.7 0.7 0.0052 16.8 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.8 EMR68247.1 - 0.011 14.9 0.7 0.06 12.5 0.6 1.9 2 0 0 2 2 2 0 NmrA-like family Methyltransf_25 PF13649.1 EMR68247.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_10 PF13460.1 EMR68247.1 - 0.029 14.3 0.3 0.088 12.8 0.2 1.8 2 0 0 2 2 2 0 NADH(P)-binding Methyltransf_18 PF12847.2 EMR68247.1 - 0.064 13.8 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ThiF PF00899.16 EMR68247.1 - 0.066 13.0 0.6 0.12 12.1 0.4 1.4 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 EMR68247.1 - 0.079 12.5 2.5 0.061 12.9 0.4 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EMR68247.1 - 0.084 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_26 PF13659.1 EMR68247.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 EMR68247.1 - 0.13 12.0 1.3 1.3 8.8 0.4 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.17 EMR68248.1 - 9.9e-30 103.4 0.0 4.8e-29 101.2 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 BBE PF08031.7 EMR68249.1 - 6.6e-09 35.5 0.1 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EMR68249.1 - 6.7e-06 25.6 0.5 1.1e-05 24.8 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain DUF4491 PF14898.1 EMR68251.1 - 0.01 15.9 0.8 0.01 15.9 0.5 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4491) DPBB_1 PF03330.13 EMR68252.1 - 1.2e-10 41.2 0.2 2.5e-10 40.2 0.2 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EMR68252.1 - 0.041 13.5 0.1 0.058 13.0 0.1 1.4 1 0 0 1 1 1 0 Barwin family zf-TFIIB PF13453.1 EMR68252.1 - 0.15 11.2 1.7 0.54 9.4 1.2 1.9 1 1 0 1 1 1 0 Transcription factor zinc-finger Metallophos PF00149.23 EMR68253.1 - 6.8e-42 143.1 1.2 1.2e-41 142.3 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase p450 PF00067.17 EMR68254.1 - 2.3e-48 164.8 0.0 2.9e-47 161.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 adh_short_C2 PF13561.1 EMR68255.1 - 4.9e-26 91.9 0.2 8.2e-26 91.2 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR68255.1 - 2.8e-21 76.1 0.2 5.1e-21 75.3 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68255.1 - 3.7e-07 29.9 0.1 9.5e-07 28.6 0.1 1.7 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EMR68255.1 - 0.0065 16.1 0.2 0.0098 15.5 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EMR68255.1 - 0.026 14.3 2.1 0.047 13.4 0.4 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EMR68255.1 - 0.044 12.9 0.1 0.11 11.6 0.1 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMR68255.1 - 0.054 13.2 0.4 0.098 12.3 0.2 1.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EMR68255.1 - 0.088 13.2 0.4 0.18 12.2 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TauD PF02668.11 EMR68256.1 - 1.5e-35 123.0 0.0 1.9e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EMR68256.1 - 0.081 13.4 0.4 0.24 11.9 0.0 2.0 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Kinesin PF00225.18 EMR68257.1 - 4.6e-54 183.3 0.0 6.3e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain AAA_24 PF13479.1 EMR68257.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain CALCOCO1 PF07888.6 EMR68258.1 - 0.0038 15.6 0.8 0.0045 15.3 0.6 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like ERM PF00769.14 EMR68258.1 - 0.34 10.3 8.8 0.6 9.6 6.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4337 PF14235.1 EMR68258.1 - 0.38 10.5 3.3 0.83 9.4 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3987 PF13148.1 EMR68258.1 - 2.6 6.4 7.3 4.3 5.7 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF869 PF05911.6 EMR68259.1 - 0.0001 20.7 22.6 0.00015 20.2 15.7 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 EMR68259.1 - 0.00012 21.4 0.4 0.00042 19.6 0.0 1.8 2 0 0 2 2 2 1 Reovirus sigma C capsid protein ERM PF00769.14 EMR68259.1 - 0.00061 19.3 19.5 0.00061 19.3 13.5 2.2 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Lebercilin PF15619.1 EMR68259.1 - 0.0039 16.6 21.8 0.0039 16.6 15.1 2.7 1 1 1 2 2 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF724 PF05266.9 EMR68259.1 - 0.0061 16.2 9.6 0.0061 16.2 6.7 3.3 1 1 2 3 3 2 2 Protein of unknown function (DUF724) Myosin_tail_1 PF01576.14 EMR68259.1 - 0.01 13.5 47.2 0.014 13.1 32.1 1.5 1 1 0 1 1 1 0 Myosin tail Tropomyosin_1 PF12718.2 EMR68259.1 - 0.021 14.6 44.6 0.11 12.3 17.5 4.6 2 1 1 4 4 3 0 Tropomyosin like Tropomyosin PF00261.15 EMR68259.1 - 0.23 10.5 46.1 8.9e+02 -1.3 12.7 2.5 1 1 0 1 1 1 0 Tropomyosin Laminin_II PF06009.7 EMR68259.1 - 0.24 11.1 15.8 0.053 13.2 4.4 2.9 1 1 1 2 2 2 0 Laminin Domain II Sec20 PF03908.8 EMR68259.1 - 0.36 10.5 2.5 0.97 9.1 0.7 2.5 1 1 1 2 2 2 0 Sec20 IncA PF04156.9 EMR68259.1 - 0.59 9.6 38.3 0.092 12.3 16.1 2.3 1 1 1 2 2 2 0 IncA protein HOOK PF05622.7 EMR68259.1 - 1.1 7.0 36.1 1.5 6.5 25.0 1.1 1 0 0 1 1 1 0 HOOK protein Laminin_I PF06008.9 EMR68259.1 - 1.8 7.8 30.1 0.07 12.4 8.0 3.2 1 1 1 3 3 3 0 Laminin Domain I Mitofilin PF09731.4 EMR68259.1 - 2.2 6.8 28.8 3 6.3 20.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TMF_DNA_bd PF12329.3 EMR68259.1 - 3.2 7.6 39.6 29 4.5 3.2 5.0 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding GAGA_bind PF06217.7 EMR68259.1 - 3.6 7.4 21.8 6.9 6.5 15.1 1.5 1 1 0 1 1 1 0 GAGA binding protein-like family DUF1664 PF07889.7 EMR68259.1 - 4.7 7.0 13.8 6.4 6.5 2.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 EMR68259.1 - 6.1 7.0 19.9 0.7 10.0 0.8 3.6 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 EMR68259.1 - 6.9 5.0 33.1 24 3.2 22.9 1.9 1 1 0 1 1 1 0 AAA domain APG6 PF04111.7 EMR68259.1 - 9.7 5.1 40.1 0.098 11.6 13.7 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 CorA PF01544.13 EMR68260.1 - 2.6e-08 33.2 0.0 5.9e-08 32.0 0.0 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2232 PF09991.4 EMR68260.1 - 0.0016 17.5 0.5 0.0022 17.0 0.4 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) TRP PF06011.7 EMR68260.1 - 0.02 13.4 0.2 0.023 13.2 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Clc-like PF07062.7 EMR68260.1 - 0.088 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Clc-like Pec_lyase_C PF00544.14 EMR68262.1 - 1.1e-36 126.2 3.8 1.5e-36 125.7 2.7 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EMR68262.1 - 1.8e-05 24.5 9.0 6.2e-05 22.8 6.2 2.0 1 1 0 1 1 1 1 Right handed beta helix region Gti1_Pac2 PF09729.4 EMR68263.1 - 0.73 9.6 8.3 0.82 9.5 0.0 2.8 3 0 0 3 3 3 0 Gti1/Pac2 family ADH_zinc_N PF00107.21 EMR68265.1 - 1.7e-27 95.5 0.6 2.5e-27 95.0 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR68265.1 - 2.4e-22 78.7 0.6 2.4e-22 78.7 0.4 1.9 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMR68265.1 - 2e-05 25.5 0.0 4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 EMR68265.1 - 0.053 13.4 0.3 0.12 12.2 0.2 1.6 1 1 0 1 1 1 0 short chain dehydrogenase DNA_ligase_OB PF03120.11 EMR68265.1 - 0.07 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain FoP_duplication PF13865.1 EMR68266.1 - 0.019 15.4 0.2 0.019 15.4 0.1 4.3 3 2 1 4 4 4 0 C-terminal duplication domain of Friend of PRMT1 SnoaL PF07366.7 EMR68266.1 - 0.1 12.1 0.8 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase TYW3 PF02676.9 EMR68267.1 - 1.1e-05 24.6 0.6 3e-05 23.2 0.4 1.8 1 0 0 1 1 1 1 Methyltransferase TYW3 ComC PF03047.9 EMR68267.1 - 0.48 9.8 3.4 1.7 8.1 0.0 3.4 3 0 0 3 3 3 0 COMC family NPV_P10 PF05531.7 EMR68267.1 - 2.4 8.4 26.5 2.3 8.5 0.2 6.8 2 1 4 6 6 6 0 Nucleopolyhedrovirus P10 protein Pox_A_type_inc PF04508.7 EMR68267.1 - 2.5 8.1 7.0 4.6 7.2 0.6 4.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Lebercilin PF15619.1 EMR68267.1 - 3.5 6.9 38.7 0.021 14.2 4.0 4.5 3 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease LsmAD PF06741.8 EMR68267.1 - 8.2 6.6 15.3 6 7.0 1.3 3.6 3 0 0 3 3 3 0 LsmAD domain YccV-like PF08755.6 EMR68268.1 - 3.3e-24 84.7 0.1 8.2e-23 80.2 0.0 2.4 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EMR68268.1 - 2e-10 40.3 0.0 3.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EMR68268.1 - 0.00011 21.8 0.4 0.00031 20.3 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMR68268.1 - 0.00093 18.7 0.1 0.0021 17.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain Acetyltransf_1 PF00583.19 EMR68269.1 - 8.4e-15 54.5 0.0 1.8e-14 53.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMR68269.1 - 3.1e-08 33.7 0.0 4.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR68269.1 - 3.7e-08 33.4 0.0 5.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR68269.1 - 2.2e-05 24.3 0.0 3e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR68269.1 - 9.7e-05 22.0 0.0 0.0003 20.4 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.1 EMR68269.1 - 0.00011 22.1 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMR68269.1 - 0.00019 21.6 0.0 0.00023 21.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMR68269.1 - 0.0049 16.7 0.0 0.0069 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EMR68271.1 - 1.6e-15 56.6 31.2 1.6e-15 56.6 21.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMR68271.1 - 1.3e-11 44.2 7.3 1.3e-11 44.2 5.1 2.9 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Daxx PF03344.10 EMR68272.1 - 2e-05 23.3 26.6 2.8e-05 22.8 18.5 1.2 1 0 0 1 1 1 1 Daxx Family TFIIF_alpha PF05793.7 EMR68272.1 - 0.0013 17.2 30.8 0.0017 16.8 21.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Spore_coat_CotO PF14153.1 EMR68272.1 - 0.0031 16.9 15.7 0.0047 16.3 10.9 1.3 1 0 0 1 1 1 1 Spore coat protein CotO Pox_Ag35 PF03286.9 EMR68272.1 - 0.024 14.1 25.3 0.052 13.0 17.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 EMR68272.1 - 0.032 12.1 37.3 0.044 11.7 25.9 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 EMR68272.1 - 0.033 13.4 19.5 0.046 12.9 13.5 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 EMR68272.1 - 0.057 11.4 28.0 0.079 10.9 19.4 1.1 1 0 0 1 1 1 0 CDC45-like protein FYDLN_acid PF09538.5 EMR68272.1 - 0.13 12.8 32.2 0.97 10.0 22.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Merozoite_SPAM PF07133.6 EMR68272.1 - 0.13 12.0 46.0 0.23 11.3 31.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SAPS PF04499.10 EMR68272.1 - 0.24 9.9 11.1 0.3 9.6 7.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.6 EMR68272.1 - 0.28 9.2 14.6 0.39 8.7 10.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ycf1 PF05758.7 EMR68272.1 - 0.31 8.6 15.7 0.4 8.3 10.9 1.1 1 0 0 1 1 1 0 Ycf1 Cwf_Cwc_15 PF04889.7 EMR68272.1 - 1.1 8.8 29.0 2.2 7.9 20.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1510 PF07423.6 EMR68272.1 - 1.2 8.4 31.1 1.9 7.7 21.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paf1 PF03985.8 EMR68272.1 - 1.3 7.6 31.4 2.2 6.9 21.7 1.3 1 0 0 1 1 1 0 Paf1 DUF2722 PF10846.3 EMR68272.1 - 1.8 7.5 10.0 2.8 6.8 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Hid1 PF12722.2 EMR68272.1 - 2 5.9 10.1 3.9 5.0 6.4 1.7 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein BUD22 PF09073.5 EMR68272.1 - 2.9 6.8 34.3 4.3 6.3 23.8 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 EMR68272.1 - 3.5 6.8 37.2 6 6.0 25.8 1.3 1 0 0 1 1 1 0 SDA1 BTV_NS2 PF04514.7 EMR68272.1 - 5.2 5.8 20.4 8.1 5.2 14.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Cytokin-bind PF09265.5 EMR68273.1 - 0.004 16.3 0.0 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding Hen1_L PF12623.2 EMR68273.1 - 0.019 13.7 0.4 0.03 13.1 0.3 1.2 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 Lipoprotein_2 PF00921.12 EMR68273.1 - 0.039 13.9 2.1 0.061 13.3 1.4 1.3 1 0 0 1 1 1 0 Borrelia lipoprotein Spc7 PF08317.6 EMR68273.1 - 0.039 12.6 1.9 0.059 12.0 1.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Cluap1 PF10234.4 EMR68273.1 - 0.099 11.8 3.7 0.15 11.2 2.6 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF4404 PF14357.1 EMR68273.1 - 0.24 11.8 3.6 3.8 8.0 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) LTXXQ PF07813.7 EMR68273.1 - 0.46 10.9 6.3 2.5 8.6 3.0 2.2 2 0 0 2 2 2 0 LTXXQ motif family protein RasGEF PF00617.14 EMR68274.1 - 6.3e-56 189.0 0.0 1.5e-55 187.8 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMR68274.1 - 7.9e-20 70.8 0.0 4.3e-19 68.5 0.0 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif Glyco_hydro_63 PF03200.11 EMR68276.1 - 1.9e-197 657.7 0.0 7.6e-196 652.4 0.0 2.4 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EMR68276.1 - 0.00054 18.7 0.0 0.00088 18.0 0.0 1.2 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 EMR68276.1 - 0.00093 18.0 0.0 0.0015 17.3 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase FoP_duplication PF13865.1 EMR68277.1 - 0.015 15.7 19.9 0.018 15.5 10.6 2.9 2 1 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Metallophos PF00149.23 EMR68278.1 - 1.6e-17 63.5 0.0 3.7e-17 62.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EMR68278.1 - 1.8e-14 53.5 1.8 2.4e-14 53.1 0.1 2.2 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EMR68278.1 - 3.8e-05 22.4 0.2 0.00015 20.4 0.2 1.9 2 1 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EMR68278.1 - 0.0044 16.8 0.0 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_S8 PF00082.17 EMR68279.1 - 2.2e-19 69.7 0.6 4e-19 68.8 0.4 1.4 1 1 0 1 1 1 1 Subtilase family Saccharop_dh PF03435.13 EMR68280.1 - 5.8e-23 81.5 0.2 7.6e-23 81.1 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EMR68280.1 - 8.1e-05 22.7 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EMR68280.1 - 0.0074 16.5 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EMR68280.1 - 0.0093 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR68280.1 - 0.047 13.6 0.1 0.2 11.6 0.1 2.2 1 1 0 1 1 1 0 NADH(P)-binding Tyrosinase PF00264.15 EMR68281.1 - 1.1e-53 182.6 2.0 1.8e-53 181.9 1.4 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Ammonium_transp PF00909.16 EMR68283.1 - 3.6e-117 391.2 29.2 4.1e-117 391.0 20.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family FMN_bind PF04205.9 EMR68283.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 FMN-binding domain TMEM107 PF14995.1 EMR68283.1 - 5.6 7.1 10.6 0.34 11.0 0.1 2.9 3 0 0 3 3 3 0 Transmembrane protein AA_permease PF00324.16 EMR68284.1 - 1.4e-122 409.5 29.1 1.5e-122 409.3 20.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR68284.1 - 1.1e-31 109.9 31.2 1.3e-31 109.6 21.6 1.1 1 0 0 1 1 1 1 Amino acid permease Cyclin_N PF00134.18 EMR68285.1 - 0.002 17.7 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EMR68285.1 - 0.025 14.5 0.1 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain Glyco_hydro_43 PF04616.9 EMR68286.1 - 4.4e-99 331.1 0.1 8.1e-99 330.3 0.1 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 AA_permease PF00324.16 EMR68287.1 - 5.7e-98 328.3 42.1 6.6e-98 328.1 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR68287.1 - 4.4e-26 91.4 43.7 5.2e-26 91.1 30.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 EMR68287.1 - 0.14 11.7 2.0 0.49 9.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2665) DUF3597 PF12200.3 EMR68288.1 - 0.042 14.2 0.8 0.042 14.2 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Dicty_REP PF05086.7 EMR68288.1 - 5.1 4.7 6.2 0.27 8.9 0.9 1.2 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein FAD_binding_4 PF01565.18 EMR68289.1 - 1.2e-14 53.9 0.2 2.4e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR68289.1 - 1.4e-09 37.7 0.0 2.8e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Y_phosphatase3 PF13350.1 EMR68290.1 - 2.3e-47 161.2 0.0 3.6e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EMR68290.1 - 2.5e-05 24.2 0.0 6.9e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EMR68290.1 - 9e-05 21.9 0.0 0.00016 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EMR68290.1 - 0.0096 15.3 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EMR68290.1 - 0.02 14.4 0.0 0.096 12.2 0.0 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EMR68290.1 - 0.094 11.4 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain ThuA PF06283.6 EMR68291.1 - 1.3e-71 240.7 0.0 1.5e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation DUF4159 PF13709.1 EMR68291.1 - 0.01 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) DUF1355 PF07090.6 EMR68291.1 - 0.027 13.8 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1355) Fungal_trans_2 PF11951.3 EMR68293.1 - 7.8e-34 116.8 2.0 1.1e-33 116.4 1.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR68293.1 - 8.2e-07 28.8 7.7 1.6e-06 27.9 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DCP1 PF06058.8 EMR68294.1 - 6.4e-16 58.5 0.0 1.1e-15 57.7 0.0 1.4 1 1 0 1 1 1 1 Dcp1-like decapping family BAR PF03114.13 EMR68295.1 - 5.2e-48 163.5 6.0 6.8e-48 163.1 4.2 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EMR68295.1 - 3.7e-06 26.0 2.9 6.2e-06 25.3 2.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking RsmJ PF04378.8 EMR68295.1 - 0.041 12.8 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA small subunit methyltransferase D, RsmJ Exo_endo_phos PF03372.18 EMR68296.1 - 8.2e-14 52.1 0.3 2.1e-13 50.7 0.1 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DIOX_N PF14226.1 EMR68297.1 - 0.0017 18.8 0.0 0.0053 17.2 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal NAD_binding_4 PF07993.7 EMR68298.1 - 3e-27 95.1 0.0 4.6e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EMR68298.1 - 1.1e-06 28.2 0.0 9.2e-06 25.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR68298.1 - 7.4e-05 22.8 0.1 0.0014 18.6 0.1 2.4 1 1 0 1 1 1 1 NADH(P)-binding PP-binding PF00550.20 EMR68298.1 - 0.0013 18.9 0.1 0.0042 17.3 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EMR68298.1 - 0.02 13.6 0.0 2.2 6.8 0.0 2.2 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EMR68298.1 - 0.031 14.5 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PIG-P PF08510.7 EMR68299.1 - 4.4e-43 145.9 2.4 6.2e-43 145.4 1.6 1.2 1 0 0 1 1 1 1 PIG-P DUF4118 PF13493.1 EMR68299.1 - 0.23 11.6 7.5 0.39 10.9 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) Actin PF00022.14 EMR68300.1 - 1.1e-140 468.5 0.0 1.3e-140 468.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EMR68300.1 - 1.2e-10 40.4 0.2 0.00051 18.7 0.0 3.1 3 0 0 3 3 3 3 MreB/Mbl protein Aldo_ket_red PF00248.16 EMR68301.1 - 1e-69 234.5 0.0 1.3e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Helitron_like_N PF14214.1 EMR68302.1 - 1.1e-58 197.9 0.1 2e-58 197.1 0.1 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EMR68302.1 - 5.5e-28 97.9 0.0 8.5e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EMR68302.1 - 5.8e-05 22.7 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF3296 PF11726.3 EMR68302.1 - 0.00045 19.8 0.0 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) ResIII PF04851.10 EMR68302.1 - 0.0022 17.8 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3416 PF11896.3 EMR68302.1 - 0.032 14.1 0.2 0.36 10.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) AAA_19 PF13245.1 EMR68302.1 - 0.033 13.9 0.1 0.08 12.7 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EMR68302.1 - 0.14 12.1 0.3 0.99 9.3 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain Enolase_C PF00113.17 EMR68303.1 - 2.5e-152 505.9 0.1 3.3e-152 505.6 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EMR68303.1 - 1.9e-57 192.8 0.4 4e-57 191.8 0.3 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 EMR68303.1 - 0.029 14.9 0.0 0.068 13.7 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 EMR68303.1 - 0.033 13.1 0.4 0.49 9.2 0.1 2.5 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 EMR68303.1 - 0.1 12.6 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 Enolase C-terminal domain-like VRR_NUC PF08774.6 EMR68306.1 - 1.3e-19 70.0 0.0 2e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 VRR-NUC domain PAT1 PF09770.4 EMR68307.1 - 8.5 4.4 9.1 10 4.1 6.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1275 PF06912.6 EMR68308.1 - 1e-37 129.4 8.3 1.2e-37 129.2 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Hydrolase_like PF13242.1 EMR68308.1 - 0.04 13.6 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like LRR_4 PF12799.2 EMR68309.1 - 3.2e-15 55.3 1.1 6.8e-06 25.5 0.8 4.3 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMR68309.1 - 1.3e-13 50.4 3.5 1.3e-07 31.2 1.8 4.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EMR68309.1 - 2.4e-07 29.8 5.1 5.6 7.4 0.0 6.5 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 EMR68309.1 - 8.5e-07 28.4 4.2 1 9.6 0.0 6.3 5 1 1 6 6 6 1 Leucine Rich repeat LRR_7 PF13504.1 EMR68309.1 - 0.0049 16.8 6.9 8 7.1 0.2 5.9 7 0 0 7 7 7 1 Leucine rich repeat LRR_9 PF14580.1 EMR68309.1 - 0.021 14.3 1.2 14 5.1 0.1 3.5 2 1 3 5 5 5 0 Leucine-rich repeat FMN_dh PF01070.13 EMR68310.1 - 1.2e-104 349.9 0.0 1.6e-104 349.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EMR68310.1 - 1.2e-20 73.0 0.0 3e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EMR68310.1 - 6.5e-07 28.5 1.0 8.5e-07 28.2 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 EMR68310.1 - 1.1e-05 24.4 0.0 0.00017 20.6 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ATP11 PF06644.6 EMR68310.1 - 0.017 14.6 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein His_biosynth PF00977.16 EMR68310.1 - 0.034 13.4 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.10 EMR68310.1 - 0.042 12.9 0.2 0.08 12.0 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.16 EMR68310.1 - 0.12 11.2 0.1 0.39 9.6 0.0 1.7 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Ribosomal_S13_N PF08069.7 EMR68311.1 - 2e-28 98.0 0.0 4e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EMR68311.1 - 4.3e-22 77.6 0.1 9.3e-22 76.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 PAX PF00292.13 EMR68311.1 - 0.052 13.2 0.1 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain MaoC_dehydratas PF01575.14 EMR68312.1 - 1.2e-21 76.3 0.0 1.9e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain ERp29_N PF07912.8 EMR68312.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 ERp29, N-terminal domain Dpy-30 PF05186.8 EMR68313.1 - 4.8e-15 54.7 0.1 6.5e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif DUF605 PF04652.11 EMR68313.1 - 8.7 5.6 12.8 11 5.3 8.9 1.2 1 0 0 1 1 1 0 Vta1 like DUF977 PF06163.6 EMR68314.1 - 0.36 10.5 4.9 2.2 8.0 0.7 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF977) Dicistro_VP4 PF11492.3 EMR68317.1 - 0.04 13.9 0.2 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 FAM104 PF15434.1 EMR68317.1 - 0.056 13.6 0.6 0.12 12.5 0.4 1.5 1 0 0 1 1 1 0 Family 104 PX PF00787.19 EMR68319.1 - 1.3e-21 76.4 0.0 2.1e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 PX domain Mpv17_PMP22 PF04117.7 EMR68320.1 - 5.9e-25 86.6 1.1 9.8e-25 85.9 0.8 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family SGL PF08450.7 EMR68321.1 - 0.0031 16.9 0.1 2.7 7.2 0.1 2.3 1 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Noc2 PF03715.8 EMR68322.1 - 1.6e-121 404.7 0.0 4e-121 403.4 0.0 1.7 1 0 0 1 1 1 1 Noc2p family Sec7_N PF12783.2 EMR68322.1 - 0.32 10.3 2.8 0.29 10.5 0.5 1.9 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Peptidase_M16 PF00675.15 EMR68323.1 - 1.1e-57 193.9 0.1 1.6e-56 190.2 0.0 2.6 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EMR68323.1 - 2.1e-39 135.1 0.1 7.7e-39 133.2 0.0 2.0 3 0 0 3 3 3 1 Peptidase M16 inactive domain Esterase PF00756.15 EMR68323.1 - 0.037 13.4 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative esterase IU_nuc_hydro PF01156.14 EMR68325.1 - 3e-68 230.3 0.1 3.3e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Sugar_tr PF00083.19 EMR68327.1 - 2.2e-102 343.0 26.5 2.5e-102 342.7 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR68327.1 - 1.9e-26 92.6 46.3 7.3e-23 80.8 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4387 PF14330.1 EMR68328.1 - 8.9e-30 102.9 0.0 2.6e-29 101.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 EMR68328.1 - 5.1e-22 77.8 0.0 5e-20 71.2 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) Gamma-thionin PF00304.15 EMR68329.1 - 0.68 9.9 13.8 1.6 8.7 0.2 3.9 3 3 0 3 3 3 0 Gamma-thionin family Sugar_tr PF00083.19 EMR68330.1 - 3.5e-38 131.3 15.8 2.7e-37 128.4 11.0 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR68330.1 - 8.1e-11 41.2 15.6 1.2e-10 40.7 10.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DNA_pol_A_exo1 PF01612.15 EMR68331.1 - 0.0018 17.8 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease PhyH PF05721.8 EMR68332.1 - 2e-09 37.7 0.0 7e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Epimerase PF01370.16 EMR68333.1 - 3.6e-10 39.6 0.1 6.5e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EMR68333.1 - 8.5e-07 29.3 0.1 2e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EMR68333.1 - 3.6e-06 25.8 0.0 0.0021 16.8 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMR68333.1 - 1.2e-05 25.4 0.0 2.5e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR68333.1 - 0.00031 20.0 0.0 0.00042 19.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EMR68333.1 - 0.0015 18.5 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.7 EMR68333.1 - 0.02 13.8 0.0 0.088 11.7 0.0 2.1 2 1 0 2 2 2 0 Male sterility protein Saccharop_dh PF03435.13 EMR68333.1 - 0.026 13.4 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase VPS28 PF03997.7 EMR68334.1 - 6.2e-54 182.4 0.1 7.3e-54 182.2 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 EMR68334.1 - 0.23 11.2 5.5 1.2 8.9 0.4 2.3 2 0 0 2 2 2 0 Gas vesicle protein G Mmp37 PF09139.6 EMR68335.1 - 2.4e-131 437.6 0.0 3e-131 437.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 DUF3455 PF11937.3 EMR68336.1 - 0.11 12.3 1.0 2.1 8.2 0.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3455) p450 PF00067.17 EMR68338.1 - 4.7e-50 170.4 0.0 6.6e-44 150.1 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 muHD PF10291.4 EMR68339.1 - 1.7e-59 201.0 0.0 4.9e-59 199.6 0.0 1.7 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EMR68339.1 - 5.1e-11 42.6 0.3 5.1e-11 42.6 0.2 2.0 2 1 1 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain V_ATPase_I PF01496.14 EMR68339.1 - 0.14 9.9 1.8 0.2 9.4 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 EMR68339.1 - 0.48 9.5 4.7 0.15 11.1 0.9 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cullin PF00888.17 EMR68340.1 - 2.1e-125 419.5 0.6 3.6e-125 418.7 0.4 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EMR68340.1 - 1.1e-25 89.2 5.1 2.3e-24 84.9 3.3 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain SapB_1 PF05184.10 EMR68340.1 - 0.02 14.7 0.5 2 8.3 0.2 2.7 2 0 0 2 2 2 0 Saposin-like type B, region 1 Phage_int_SAM_4 PF13495.1 EMR68340.1 - 0.12 12.7 1.4 2.1 8.7 1.0 2.8 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain MAD PF05557.8 EMR68342.1 - 6.8e-56 189.7 56.0 9e-56 189.3 38.8 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Apq12 PF12716.2 EMR68343.1 - 8e-05 22.2 11.8 0.00015 21.3 8.2 1.5 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis VirB8 PF04335.8 EMR68343.1 - 0.37 10.3 5.7 0.13 11.7 2.0 1.6 1 1 1 2 2 2 0 VirB8 protein CcmD PF04995.9 EMR68343.1 - 1.1 9.0 7.0 0.89 9.3 1.0 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) adh_short PF00106.20 EMR68344.1 - 9e-12 45.2 0.1 1.4e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68344.1 - 9.6e-05 22.1 0.1 0.00015 21.5 0.1 1.2 1 0 0 1 1 1 1 KR domain ATP_bind_1 PF03029.12 EMR68345.1 - 1.3e-71 240.9 0.0 3e-71 239.7 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EMR68345.1 - 1.4e-05 25.9 0.0 4.1e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMR68345.1 - 0.00084 19.2 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EMR68345.1 - 0.0026 17.2 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EMR68345.1 - 0.0029 17.4 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EMR68345.1 - 0.0032 17.6 0.0 0.0061 16.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.18 EMR68345.1 - 0.0066 16.3 0.0 0.016 15.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EMR68345.1 - 0.0073 16.3 0.0 0.049 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMR68345.1 - 0.0097 16.0 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EMR68345.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EMR68345.1 - 0.016 14.5 0.0 4.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase CbiA PF01656.18 EMR68345.1 - 0.017 14.5 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.22 EMR68345.1 - 0.024 14.9 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 EMR68345.1 - 0.03 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EMR68345.1 - 0.036 13.5 0.0 0.086 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain Septin PF00735.13 EMR68345.1 - 0.038 13.0 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_31 PF13614.1 EMR68345.1 - 0.041 13.8 0.0 0.16 11.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMR68345.1 - 0.055 13.7 0.4 0.26 11.5 0.0 2.3 2 2 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EMR68345.1 - 0.062 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain TRADD_N PF09034.5 EMR68345.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 TRADD, N-terminal domain GTP_EFTU PF00009.22 EMR68345.1 - 0.069 12.5 0.0 3.1 7.1 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EMR68345.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.14 EMR68345.1 - 0.081 12.3 0.0 7.5 5.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 EMR68345.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.24 EMR68345.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EMR68345.1 - 0.11 11.8 0.2 0.38 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EMR68345.1 - 0.12 12.2 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 EMR68345.1 - 0.12 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 EMR68345.1 - 0.13 11.7 0.0 0.69 9.3 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EMR68345.1 - 0.13 11.8 0.2 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EMR68345.1 - 0.15 11.5 0.0 0.39 10.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein PPV_E1_C PF00519.12 EMR68345.1 - 0.17 10.4 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Oxidored_FMN PF00724.15 EMR68346.1 - 9.5e-53 179.3 0.0 1.3e-41 142.7 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EMR68346.1 - 4.1e-06 25.8 0.1 9.1e-05 21.4 0.0 2.3 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EMR68346.1 - 0.041 13.1 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein S-AdoMet_synt_C PF02773.11 EMR68348.1 - 1.5e-72 241.7 0.2 2.4e-72 241.1 0.1 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EMR68348.1 - 2.7e-43 146.7 0.0 4.5e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EMR68348.1 - 7.2e-42 141.6 0.1 1.6e-41 140.5 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Amidinotransf PF02274.12 EMR68348.1 - 0.0047 16.0 0.0 0.06 12.4 0.0 2.0 2 0 0 2 2 2 1 Amidinotransferase IU_nuc_hydro PF01156.14 EMR68349.1 - 3.9e-07 29.6 0.0 6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase COX5A PF02284.11 EMR68352.1 - 3.8e-40 136.1 0.5 4.7e-40 135.9 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Synthase_beta PF11421.3 EMR68352.1 - 0.45 11.2 3.7 0.99 10.1 2.5 1.7 1 1 0 1 1 1 0 ATP synthase F1 beta subunit 6PGD PF00393.14 EMR68353.1 - 3.4e-59 200.4 0.0 5.6e-59 199.7 0.0 1.3 1 1 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EMR68353.1 - 1.6e-31 109.3 0.0 2.8e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EMR68353.1 - 2e-05 24.0 0.0 4.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EMR68353.1 - 3.6e-05 22.9 0.0 6.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EMR68353.1 - 5.6e-05 22.8 0.1 0.00017 21.3 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMR68353.1 - 0.0003 20.5 0.0 0.0006 19.5 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EMR68353.1 - 0.05 12.9 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EMR68353.1 - 0.082 13.3 0.0 0.26 11.7 0.0 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 EMR68353.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ERM PF00769.14 EMR68354.1 - 0.00014 21.5 30.5 0.0038 16.8 8.4 2.2 1 1 1 2 2 2 2 Ezrin/radixin/moesin family DUF4201 PF13870.1 EMR68354.1 - 0.00025 20.5 21.7 0.00057 19.3 7.9 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) SCP-1 PF05483.7 EMR68354.1 - 0.003 15.4 5.1 0.003 15.4 3.5 2.7 1 1 2 3 3 3 1 Synaptonemal complex protein 1 (SCP-1) CENP-F_leu_zip PF10473.4 EMR68354.1 - 0.011 15.5 31.3 0.063 13.1 9.5 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 EMR68354.1 - 0.016 12.5 29.0 0.15 9.3 10.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TBPIP PF07106.8 EMR68354.1 - 0.026 14.0 0.9 0.026 14.0 0.6 3.2 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Lipoprotein_7 PF01540.11 EMR68354.1 - 0.067 12.2 7.0 0.091 11.8 3.8 2.1 1 1 0 1 1 1 0 Adhesin lipoprotein NYD-SP28_assoc PF14775.1 EMR68354.1 - 0.068 12.8 3.1 6.9 6.4 0.4 3.7 2 1 0 2 2 2 0 Sperm tail C-terminal domain Filament PF00038.16 EMR68354.1 - 0.11 12.0 25.8 0.11 11.8 9.7 2.6 1 1 0 2 2 2 0 Intermediate filament protein DUF972 PF06156.8 EMR68354.1 - 0.73 10.2 21.3 0.46 10.8 3.3 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF972) WEMBL PF05701.6 EMR68354.1 - 1.2 7.4 30.4 1.9 6.8 6.5 3.1 1 1 1 3 3 3 0 Weak chloroplast movement under blue light Laminin_II PF06009.7 EMR68354.1 - 1.3 8.7 13.3 0.71 9.6 1.6 3.2 1 1 1 2 2 2 0 Laminin Domain II Tropomyosin_1 PF12718.2 EMR68354.1 - 2.2 8.1 29.9 0.09 12.6 14.0 2.6 2 1 1 3 3 3 0 Tropomyosin like UPF0242 PF06785.6 EMR68354.1 - 3.1 6.3 20.1 3.2 6.3 4.6 2.1 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) TMF_DNA_bd PF12329.3 EMR68354.1 - 3.2 7.6 30.7 0.076 12.8 0.9 4.4 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 EMR68354.1 - 3.3 7.4 28.0 5.5 6.7 5.8 3.5 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) ELO PF01151.13 EMR68355.1 - 1.3e-62 211.3 16.6 1.7e-62 211.0 11.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4149 PF13664.1 EMR68355.1 - 0.24 11.4 4.3 0.36 10.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF1772 PF08592.6 EMR68356.1 - 2e-15 56.7 2.4 3.4e-15 55.9 1.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Nodulin_late PF07127.6 EMR68357.1 - 0.071 13.2 0.3 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Late nodulin protein PGG PF13962.1 EMR68357.1 - 0.24 11.0 0.9 0.31 10.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function EB PF01683.13 EMR68357.1 - 6.1 6.9 9.6 8.5 6.5 5.5 2.0 1 1 1 2 2 2 0 EB module Phage_Mu_Gam PF07352.7 EMR68358.1 - 0.055 12.9 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein AMP-binding PF00501.23 EMR68359.1 - 2.2e-15 56.0 0.5 5e-15 54.8 0.3 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMR68359.1 - 1.3e-10 42.0 0.0 2.5e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HSF_DNA-bind PF00447.12 EMR68360.1 - 1.8e-16 60.1 2.4 2.5e-16 59.7 1.6 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.17 EMR68360.1 - 0.14 12.2 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Ets-domain rve PF00665.21 EMR68361.1 - 1.1e-07 31.9 0.0 8.6e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_3 PF13456.1 EMR68361.1 - 2.1e-05 24.2 0.0 4.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like zf-H2C2 PF09337.5 EMR68361.1 - 0.0011 18.2 0.2 0.0028 17.0 0.1 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVP PF00077.15 EMR68362.1 - 0.0001 22.1 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EMR68362.1 - 0.007 16.8 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.1 EMR68362.1 - 0.04 13.4 0.6 0.11 12.0 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2 PF00096.21 EMR68363.1 - 5.2e-06 26.4 10.9 1.1e-05 25.4 2.6 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EMR68363.1 - 2e-05 24.6 3.8 2e-05 24.6 2.7 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMR68363.1 - 0.00039 20.5 0.9 0.00039 20.5 0.6 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMR68363.1 - 0.00058 19.9 2.3 0.00066 19.7 0.7 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMR68363.1 - 0.13 12.5 2.1 0.23 11.6 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EMR68363.1 - 0.23 11.3 1.6 0.44 10.5 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMR68363.1 - 0.57 10.3 2.7 0.83 9.8 0.5 2.2 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) ARS2 PF04959.8 EMR68363.1 - 0.83 9.8 4.0 2.7 8.1 2.8 1.9 1 1 0 1 1 1 0 Arsenite-resistance protein 2 CAF1 PF04857.15 EMR68364.1 - 0.025 13.9 0.2 0.92 8.7 0.1 2.6 1 1 0 1 1 1 0 CAF1 family ribonuclease DUF4149 PF13664.1 EMR68365.1 - 5.9e-18 64.7 4.7 3.5e-17 62.3 1.7 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4149) DUF368 PF04018.8 EMR68365.1 - 0.073 12.2 0.3 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF368) Ribosomal_L24e PF01246.15 EMR68367.1 - 6.6e-31 105.9 2.8 1.5e-30 104.8 2.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Ku PF02735.11 EMR68368.1 - 1.6e-24 86.4 0.0 2.6e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EMR68368.1 - 5.9e-23 81.4 0.0 1e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EMR68368.1 - 6.4e-17 61.5 0.0 1.6e-16 60.3 0.0 1.6 2 0 0 2 2 2 1 Ku C terminal domain like VWA_2 PF13519.1 EMR68368.1 - 2.2e-06 27.8 0.0 9.7e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain ING PF12998.2 EMR68370.1 - 0.00096 19.3 0.0 0.0025 18.0 0.0 1.8 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EMR68370.1 - 0.21 11.3 7.8 0.7 9.6 0.7 2.4 2 0 0 2 2 2 0 PHD-finger Topoisom_bac PF01131.15 EMR68371.1 - 9e-75 251.9 0.1 1.4e-69 234.8 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 EMR68371.1 - 5.8e-17 61.5 0.0 1.2e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Toprim domain RdRP_1 PF00680.15 EMR68371.1 - 0.063 11.5 0.0 0.11 10.6 0.0 1.3 1 0 0 1 1 1 0 RNA dependent RNA polymerase TATR PF03430.8 EMR68372.1 - 0.15 10.6 5.4 0.3 9.6 3.7 1.5 1 1 0 1 1 1 0 Trans-activating transcriptional regulator Dicty_REP PF05086.7 EMR68372.1 - 0.38 8.4 4.8 0.5 8.0 3.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DnaJ PF00226.26 EMR68373.1 - 7.5e-08 32.0 0.0 1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EMR68373.1 - 1.6e-05 24.6 0.0 1.8e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.1 EMR68373.1 - 0.014 14.6 0.9 0.014 14.6 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) Rad60-SLD PF11976.3 EMR68375.1 - 2.6e-07 30.1 0.0 5.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EMR68375.1 - 0.0048 16.2 0.0 0.0094 15.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF3354 PF11834.3 EMR68375.1 - 0.045 13.3 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) PB1 PF00564.19 EMR68375.1 - 0.046 13.3 0.0 0.45 10.1 0.0 2.3 2 0 0 2 2 2 0 PB1 domain DUF3602 PF12223.3 EMR68377.1 - 2.4e-09 37.4 24.1 0.0091 16.3 4.2 3.6 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Stb3 PF10330.4 EMR68378.1 - 7.2e-36 121.7 0.0 1.3e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein NnrS PF05940.7 EMR68378.1 - 0.23 10.2 0.8 0.3 9.9 0.0 1.5 2 0 0 2 2 2 0 NnrS protein Prenyltrans PF00432.16 EMR68379.1 - 6.9e-29 99.1 4.9 1.1e-09 37.7 0.1 5.0 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EMR68379.1 - 2.4e-24 85.4 0.1 2.4e-10 40.3 0.0 6.3 3 2 4 7 7 7 6 Prenyltransferase-like Prenyltrans_2 PF13249.1 EMR68379.1 - 3.5e-24 85.3 1.9 7e-16 58.6 0.0 4.9 4 1 1 5 5 5 4 Prenyltransferase-like A2M_comp PF07678.9 EMR68379.1 - 2.5e-05 23.6 0.3 9.4e-05 21.7 0.1 2.0 1 1 1 2 2 2 1 A-macroglobulin complement component Pec_lyase PF09492.5 EMR68379.1 - 3.1e-05 23.2 0.1 0.82 8.7 0.0 4.0 2 1 2 4 4 4 2 Pectic acid lyase Abhydrolase_6 PF12697.2 EMR68380.1 - 3.7e-18 66.2 0.2 4.9e-18 65.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR68380.1 - 1.7e-13 50.7 0.0 2.1e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR68380.1 - 4.1e-08 33.0 0.0 8.1e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EMR68380.1 - 0.00051 18.6 0.0 0.00065 18.2 0.0 1.1 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 EMR68380.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.3 EMR68380.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Tannase PF07519.6 EMR68380.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase GKAP PF03359.8 EMR68381.1 - 0.35 10.4 8.1 0.48 9.9 5.6 1.1 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein PHO4 PF01384.15 EMR68382.1 - 6.1e-100 334.0 18.4 7.1e-100 333.8 12.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family Syndecan PF01034.15 EMR68382.1 - 0.058 13.0 2.8 0.11 12.1 0.2 2.9 2 0 0 2 2 2 0 Syndecan domain Pedibin PF08182.6 EMR68382.1 - 0.18 11.3 0.3 0.46 10.0 0.2 1.6 2 0 0 2 2 2 0 Pedibin/Hym-346 family SGS PF05002.10 EMR68383.1 - 8.2e-29 99.1 2.5 2.6e-28 97.5 1.7 1.9 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EMR68383.1 - 5.9e-12 45.9 0.4 1.1e-11 45.1 0.2 1.5 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EMR68383.1 - 1.1e-09 37.8 0.2 2.7e-08 33.3 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EMR68383.1 - 7.7e-09 34.8 0.8 0.011 15.6 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMR68383.1 - 3e-07 30.9 2.2 1.2e-05 25.8 0.4 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMR68383.1 - 4.4e-05 22.9 0.7 1.8 8.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMR68383.1 - 0.006 16.8 0.2 0.85 10.0 0.0 3.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMR68383.1 - 0.15 12.7 3.7 38 5.2 0.2 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMR68383.1 - 0.62 10.0 3.1 0.58 10.1 0.2 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4267 PF14087.1 EMR68384.1 - 1.5e-15 56.8 2.3 1.7e-15 56.5 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) TIG PF01833.19 EMR68385.1 - 0.11 12.5 3.1 0.25 11.3 1.3 2.2 2 0 0 2 2 2 0 IPT/TIG domain Sugar_tr PF00083.19 EMR68386.1 - 5.5e-93 312.0 22.8 6.2e-93 311.8 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR68386.1 - 5.3e-19 68.1 56.0 5.4e-18 64.8 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR68386.1 - 0.00046 18.5 0.3 0.00083 17.6 0.2 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EMR68386.1 - 0.0019 16.7 0.8 0.0019 16.7 0.6 2.8 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 EMR68387.1 - 1.1e-18 67.0 51.1 1.9e-11 43.2 19.2 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR68387.1 - 1.5e-13 49.8 24.8 3.3e-13 48.7 17.2 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 EMR68388.1 - 1.7e-57 194.9 0.0 2.3e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EMR68389.1 - 0.0033 16.3 0.1 0.0054 15.6 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EMR68390.1 - 2.1e-06 26.8 0.0 3.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain BBE PF08031.7 EMR68392.1 - 3.2e-09 36.5 0.0 7.2e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 EMR68393.1 - 8.3e-14 51.8 1.1 9.5e-14 51.6 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68393.1 - 4.6e-09 36.1 0.3 5.6e-09 35.9 0.2 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR68393.1 - 8.4e-05 22.4 0.1 0.0001 22.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EMR68393.1 - 0.0069 16.1 0.7 0.019 14.7 0.5 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_2 PF03446.10 EMR68393.1 - 0.011 15.6 0.4 0.013 15.3 0.3 1.1 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 EMR68393.1 - 0.011 14.7 0.9 0.012 14.5 0.6 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ldh_1_N PF00056.18 EMR68393.1 - 0.029 14.1 0.6 0.062 13.1 0.3 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.16 EMR68393.1 - 0.031 13.7 0.3 0.041 13.3 0.2 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMR68393.1 - 0.033 13.0 0.4 0.036 12.9 0.3 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3186 PF11382.3 EMR68394.1 - 0.0073 15.4 0.6 0.01 15.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3186) COG4 PF08318.7 EMR68394.1 - 0.019 13.7 0.1 0.023 13.4 0.1 1.2 1 0 0 1 1 1 0 COG4 transport protein Med3 PF11593.3 EMR68394.1 - 0.031 13.5 1.5 0.042 13.0 1.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4349 PF14257.1 EMR68394.1 - 0.078 12.1 3.2 0.12 11.6 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) TBPIP PF07106.8 EMR68394.1 - 0.082 12.4 6.5 0.12 11.8 1.2 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Phage_GP20 PF06810.6 EMR68394.1 - 0.14 11.5 2.4 0.6 9.5 0.4 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Striatin PF08232.7 EMR68394.1 - 0.29 11.4 11.2 0.15 12.3 2.3 2.3 2 0 0 2 2 2 0 Striatin family CALCOCO1 PF07888.6 EMR68394.1 - 0.31 9.2 10.3 1 7.5 7.2 1.7 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.9 EMR68394.1 - 0.49 9.9 14.2 24 4.4 9.9 2.1 1 1 0 1 1 1 0 IncA protein Atg14 PF10186.4 EMR68394.1 - 0.5 9.2 11.7 2.3 7.1 3.0 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Bap31 PF05529.7 EMR68394.1 - 0.71 9.2 4.7 0.34 10.3 0.9 1.9 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF4140 PF13600.1 EMR68394.1 - 0.88 10.0 7.3 1.1 9.7 1.3 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF724 PF05266.9 EMR68394.1 - 0.95 9.0 7.6 0.11 12.1 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) SlyX PF04102.7 EMR68394.1 - 0.96 9.8 4.1 1.1 9.6 0.7 2.5 2 1 0 2 2 2 0 SlyX DUF641 PF04859.7 EMR68394.1 - 1.1 9.0 7.7 0.72 9.6 1.6 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF2203 PF09969.4 EMR68394.1 - 1.8 8.7 4.6 10 6.3 3.1 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF1319 PF07028.6 EMR68394.1 - 3.4 7.8 7.3 8.7 6.5 0.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1319) APG6 PF04111.7 EMR68394.1 - 7 5.6 12.5 0.77 8.7 3.4 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 EMR68394.1 - 9.4 6.6 7.8 3.5 8.0 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IBR PF01485.16 EMR68395.1 - 1.9e-11 43.6 32.2 9.9e-08 31.7 6.3 3.2 3 0 0 3 3 3 2 IBR domain zf-RING_5 PF14634.1 EMR68395.1 - 0.015 15.0 6.5 0.015 15.0 4.5 4.2 3 2 0 3 3 3 0 zinc-RING finger domain MFS_1 PF07690.11 EMR68396.1 - 8.8e-18 64.1 47.5 2.8e-16 59.1 14.9 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR68396.1 - 8.7e-09 34.4 13.2 8.7e-09 34.4 9.2 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter DUF1726 PF08351.6 EMR68396.1 - 0.016 14.9 0.3 0.037 13.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) DUF3357 PF11837.3 EMR68396.1 - 0.047 13.5 1.2 4.1 7.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) ADH_zinc_N PF00107.21 EMR68397.1 - 5.8e-20 71.1 1.5 7.9e-20 70.7 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR68397.1 - 1.5e-05 24.6 0.1 3.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF1593 PF07632.6 EMR68398.1 - 5.4e-78 261.8 0.0 7.8e-78 261.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) adh_short PF00106.20 EMR68399.1 - 1.5e-13 51.0 0.0 2.4e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68399.1 - 1.7e-05 24.5 0.0 2.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 KR domain zf-MYND PF01753.13 EMR68400.1 - 1.8e-08 34.1 11.2 3.6e-08 33.1 7.8 1.6 1 0 0 1 1 1 1 MYND finger SET PF00856.23 EMR68400.1 - 3.1e-08 34.0 0.0 9.4e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 SET domain FolB PF02152.13 EMR68401.1 - 3e-07 30.5 0.0 3.3e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Dihydroneopterin aldolase Acetyltransf_1 PF00583.19 EMR68401.1 - 5.4e-07 29.5 0.0 1.7e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR68401.1 - 5e-05 23.3 0.0 8.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR68401.1 - 0.0026 17.8 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR68401.1 - 0.012 15.3 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein TPR_11 PF13414.1 EMR68403.1 - 2.4e-24 84.7 8.1 6.7e-10 38.4 0.4 4.4 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 EMR68403.1 - 9.7e-24 81.9 1.7 8.9e-08 31.4 0.0 5.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EMR68403.1 - 1.7e-21 74.3 6.8 3e-06 26.7 0.1 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMR68403.1 - 3.3e-17 62.6 11.4 3.9e-07 30.5 0.2 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMR68403.1 - 7.8e-16 56.8 1.7 0.023 14.8 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMR68403.1 - 5.6e-14 51.3 15.0 4.4e-05 23.7 0.1 6.2 3 2 4 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EMR68403.1 - 2.9e-12 46.7 6.2 0.0024 18.1 2.1 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 EMR68403.1 - 2.8e-11 42.3 4.8 0.0023 17.5 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMR68403.1 - 6.8e-11 41.9 11.9 1.7e-08 34.2 0.3 4.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMR68403.1 - 1e-09 37.4 0.5 0.00062 19.3 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EMR68403.1 - 7.8e-09 35.2 4.5 0.0002 21.1 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 EMR68403.1 - 5.7e-08 32.7 3.7 0.042 13.9 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EMR68403.1 - 9.9e-06 25.6 2.7 0.016 15.3 0.3 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EMR68403.1 - 2.4e-05 24.4 9.9 0.28 11.7 0.1 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_3 PF07720.7 EMR68403.1 - 0.00024 20.8 0.0 0.19 11.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMR68403.1 - 0.00037 20.3 3.0 1 9.4 0.2 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF1641 PF07849.6 EMR68403.1 - 0.16 11.6 0.2 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) DED PF01335.16 EMR68403.1 - 0.27 11.3 1.5 9.5 6.4 0.0 2.6 3 0 0 3 3 2 0 Death effector domain RNase_T PF00929.19 EMR68404.1 - 2.1e-26 93.1 0.0 5.7e-26 91.7 0.0 1.7 2 0 0 2 2 2 1 Exonuclease p450 PF00067.17 EMR68405.1 - 2.4e-54 184.5 0.0 3e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMR68406.1 - 8.7e-29 100.3 0.0 1.3e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAST_2 PF08368.7 EMR68407.1 - 0.041 14.2 0.2 7.7 6.9 0.0 2.4 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 Glyco_hydro_76 PF03663.9 EMR68408.1 - 3.4e-108 362.3 18.0 4.3e-108 362.0 12.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 RINGv PF12906.2 EMR68409.1 - 4.6e-05 23.3 4.0 7.2e-05 22.7 2.8 1.3 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EMR68409.1 - 0.00032 20.6 1.0 0.00056 19.8 0.7 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EMR68409.1 - 0.00065 19.4 3.9 0.001 18.8 2.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMR68409.1 - 0.049 13.3 1.2 0.087 12.5 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMR68409.1 - 0.13 12.3 3.1 0.25 11.3 2.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMR68409.1 - 0.17 12.0 1.2 0.29 11.2 0.8 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger PHD PF00628.24 EMR68409.1 - 0.38 10.4 3.2 0.66 9.7 2.2 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 EMR68409.1 - 1.4 8.5 4.3 2.6 7.6 3.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Lactonase PF10282.4 EMR68410.1 - 2.6e-22 79.3 0.0 5.7e-22 78.2 0.0 1.6 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NmrA PF05368.8 EMR68411.1 - 1e-20 73.9 0.0 1.3e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR68411.1 - 1e-12 48.4 0.0 1.6e-12 47.8 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR68411.1 - 3.9e-08 33.0 0.2 1.5e-07 31.1 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMR68411.1 - 2.9e-07 30.5 1.6 3.3e-07 30.3 0.5 1.5 2 0 0 2 2 2 1 short chain dehydrogenase Saccharop_dh PF03435.13 EMR68411.1 - 2.3e-06 26.8 0.3 3.5e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 EMR68411.1 - 5.3e-06 26.2 0.5 8.6e-06 25.5 0.3 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EMR68411.1 - 3.7e-05 22.5 0.0 5.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EMR68411.1 - 9.1e-05 22.4 1.1 0.00022 21.1 0.2 1.9 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_4 PF07993.7 EMR68411.1 - 0.00062 18.7 0.1 0.00096 18.1 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein F420_oxidored PF03807.12 EMR68411.1 - 0.00094 19.5 0.7 0.002 18.5 0.2 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 EMR68411.1 - 0.00098 19.0 0.6 0.0024 17.7 0.4 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EMR68411.1 - 0.0018 17.2 0.3 0.0047 15.8 0.2 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EMR68411.1 - 0.0034 17.6 0.1 0.0072 16.6 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMR68411.1 - 0.0048 17.0 0.4 0.016 15.3 0.1 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EMR68411.1 - 0.012 15.0 0.1 0.034 13.5 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.12 EMR68411.1 - 0.021 13.7 0.2 0.042 12.7 0.1 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain DUF456 PF04306.8 EMR68413.1 - 9.5e-06 25.6 7.1 1e-05 25.5 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.1 EMR68413.1 - 0.0094 15.5 21.3 0.0094 15.5 14.8 2.3 2 1 1 3 3 3 1 Glycine zipper Transgly_assoc PF04226.8 EMR68413.1 - 0.058 13.4 0.4 0.058 13.4 0.3 2.6 1 1 1 2 2 2 0 Transglycosylase associated protein DUF575 PF04746.7 EMR68413.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF575) Gly-zipper_YMGG PF13441.1 EMR68413.1 - 0.76 9.3 27.0 0.044 13.3 14.4 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 EMR68413.1 - 1.7 8.3 32.3 0.27 10.9 16.0 3.0 2 1 1 3 3 3 0 Glycine zipper 2TM domain Patatin PF01734.17 EMR68414.1 - 7.2e-27 94.6 0.0 1e-26 94.1 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Cupin_1 PF00190.17 EMR68415.1 - 2.8e-31 107.8 0.0 6.3e-16 58.1 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EMR68415.1 - 1.2e-27 95.2 1.6 1.2e-13 50.2 0.3 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EMR68415.1 - 2e-08 33.4 0.1 0.00041 19.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EMR68415.1 - 1.5e-07 31.2 0.2 0.00036 20.2 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.13 EMR68415.1 - 0.0027 17.3 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.9 EMR68415.1 - 0.022 14.6 0.6 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.7 EMR68415.1 - 0.047 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Cupin_7 PF12973.2 EMR68415.1 - 0.095 12.5 0.2 0.5 10.2 0.0 2.3 2 1 0 2 2 2 0 ChrR Cupin-like domain 2OG-FeII_Oxy_5 PF13759.1 EMR68415.1 - 0.12 12.6 0.1 11 6.3 0.0 3.1 2 1 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase GPI PF06560.6 EMR68415.1 - 0.16 10.9 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Sulfate_transp PF00916.15 EMR68416.1 - 8.2e-52 175.9 7.0 1.8e-51 174.8 3.0 2.2 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMR68416.1 - 1.3e-22 79.2 2.5 1.3e-22 79.2 1.7 3.8 4 1 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMR68416.1 - 2.6e-07 30.0 0.0 4.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 STAS domain B12D PF06522.6 EMR68416.1 - 0.032 13.9 0.6 0.18 11.5 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit NAD_binding_4 PF07993.7 EMR68418.1 - 1.3e-33 115.9 0.0 2.5e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EMR68418.1 - 8.7e-22 77.0 0.0 1.4e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EMR68418.1 - 6e-11 42.2 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMR68418.1 - 1.3e-10 41.3 0.0 3.7e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 EMR68418.1 - 3e-06 27.2 0.5 1e-05 25.5 0.3 1.9 1 0 0 1 1 1 1 short chain dehydrogenase DUF1275 PF06912.6 EMR68419.1 - 1.7e-39 135.2 14.9 2.2e-39 134.8 10.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Fungal_trans PF04082.13 EMR68420.1 - 0.00016 20.6 0.0 0.00022 20.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Oxysterol_BP PF01237.13 EMR68421.1 - 1.7e-85 286.6 0.0 2.1e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein MAR_sialic_bdg PF10564.4 EMR68422.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Sialic-acid binding micronemal adhesive repeat zf-4CXXC_R1 PF10497.4 EMR68422.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 MFS_1 PF07690.11 EMR68424.1 - 3.3e-16 58.9 45.2 4.5e-14 51.9 28.2 3.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Imm10 PF15562.1 EMR68424.1 - 0.0084 15.8 7.4 1.3 8.8 0.2 3.2 2 0 0 2 2 2 2 Immunity protein 10 Tmemb_18A PF09771.4 EMR68424.1 - 0.055 13.4 1.7 0.11 12.5 1.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 DUF2648 PF10855.3 EMR68424.1 - 0.15 11.5 0.4 0.54 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2648) DUF2178 PF09946.4 EMR68424.1 - 0.17 11.6 2.2 0.75 9.5 1.5 2.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DPM3 PF08285.6 EMR68424.1 - 1.3 8.9 4.1 0.68 9.8 0.1 2.3 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PepSY_TM_2 PF13703.1 EMR68424.1 - 9.4 6.4 17.4 0.58 10.3 0.4 3.8 3 1 1 4 4 4 0 PepSY-associated TM helix ketoacyl-synt PF00109.21 EMR68425.1 - 3.5e-66 223.2 0.0 7.9e-66 222.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Carn_acyltransf PF00755.15 EMR68425.1 - 6.2e-63 212.8 0.0 8.7e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Acyl_transf_1 PF00698.16 EMR68425.1 - 2.1e-61 208.0 0.4 4.7e-61 206.8 0.3 1.7 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EMR68425.1 - 4.8e-53 180.2 1.8 9e-53 179.3 0.1 2.4 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EMR68425.1 - 8.4e-35 119.1 0.1 2.4e-34 117.7 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EMR68425.1 - 2.3e-27 95.8 6.1 1e-19 70.9 0.1 3.7 2 1 1 3 3 3 2 KR domain adh_short PF00106.20 EMR68425.1 - 1.6e-17 63.8 9.5 1.2e-11 44.8 0.2 4.4 3 1 1 4 4 4 2 short chain dehydrogenase PP-binding PF00550.20 EMR68425.1 - 6.3e-06 26.3 0.2 2.1e-05 24.6 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 EMR68425.1 - 0.0002 20.9 0.4 0.00067 19.2 0.3 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase WSC PF01822.14 EMR68426.1 - 2.2e-18 65.9 2.9 2.2e-18 65.9 2.0 2.0 2 0 0 2 2 2 1 WSC domain SSP160 PF06933.6 EMR68426.1 - 0.16 9.9 18.8 0.2 9.5 13.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 EMR68426.1 - 1.6 6.4 5.3 2 6.1 3.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 EMR68426.1 - 6.9 6.4 36.0 9.1 6.0 24.9 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein Peptidase_M28 PF04389.12 EMR68428.1 - 8.5e-31 107.0 0.0 1.3e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMR68428.1 - 1.2e-11 44.2 0.2 3e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 PA domain Cpn60_TCP1 PF00118.19 EMR68429.1 - 6.2e-119 397.7 9.5 7.2e-119 397.5 6.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family adh_short PF00106.20 EMR68430.1 - 1.2e-08 35.0 0.0 2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68430.1 - 0.086 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 KR domain QCR10 PF09796.4 EMR68431.1 - 0.11 12.1 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Inositol_P PF00459.20 EMR68432.1 - 3.8e-35 121.5 0.1 7.6e-35 120.5 0.0 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family DUF4611 PF15387.1 EMR68433.1 - 0.85 9.7 6.9 0.21 11.7 1.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) Glucosamine_iso PF01182.15 EMR68434.1 - 8.9e-59 198.5 0.0 1.1e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF2361 PF10153.4 EMR68435.1 - 2.3e-32 111.5 8.2 6.1e-32 110.1 5.7 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) She9_MDM33 PF05546.6 EMR68435.1 - 0.091 12.2 3.7 0.14 11.6 2.5 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family Fib_alpha PF08702.5 EMR68435.1 - 3.5 7.7 8.7 0.76 9.8 3.6 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ketoacyl-synt PF00109.21 EMR68436.1 - 3e-57 194.0 1.5 1e-55 188.9 0.4 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ubiq_cyt_C_chap PF03981.7 EMR68436.1 - 9.5e-38 129.2 1.2 2.5e-37 127.8 0.8 1.7 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Ketoacyl-synt_C PF02801.17 EMR68436.1 - 2.1e-20 72.7 0.1 2.7e-18 65.9 0.1 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EMR68436.1 - 4e-07 29.2 0.1 3.8e-05 22.8 0.0 3.0 3 0 0 3 3 3 1 Thiolase, N-terminal domain AAA_12 PF13087.1 EMR68437.1 - 7.1e-27 94.0 0.0 1.2e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMR68437.1 - 7.7e-05 22.3 2.8 0.00079 19.0 1.9 2.4 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EMR68437.1 - 0.00031 20.8 0.2 0.0013 18.8 0.0 2.2 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain TPR_11 PF13414.1 EMR68438.1 - 1.6e-32 110.9 19.9 7.8e-07 28.6 0.1 11.2 7 4 1 11 11 11 6 TPR repeat TPR_2 PF07719.12 EMR68438.1 - 4.7e-26 88.5 12.4 0.0068 16.2 0.0 11.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.23 EMR68438.1 - 1.3e-24 84.7 16.4 3.3e-05 23.2 0.1 11.7 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_8 PF13181.1 EMR68438.1 - 4.8e-23 79.1 17.0 8.5e-06 25.1 0.3 11.6 12 1 0 12 12 12 5 Tetratricopeptide repeat TPR_12 PF13424.1 EMR68438.1 - 2.7e-22 78.4 10.8 6.2e-06 26.0 0.0 9.3 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMR68438.1 - 2.7e-17 61.6 28.5 0.00096 19.5 0.0 12.9 12 3 3 15 15 13 5 Tetratricopeptide repeat TPR_7 PF13176.1 EMR68438.1 - 3.6e-16 57.6 16.4 0.00051 19.6 0.0 10.1 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_6 PF13174.1 EMR68438.1 - 1.8e-14 53.0 16.6 0.00073 19.8 0.0 10.5 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.1 EMR68438.1 - 3.3e-14 52.9 32.1 8.4e-07 29.2 0.5 11.1 10 3 2 13 13 13 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMR68438.1 - 4e-14 52.8 29.3 0.013 16.1 0.4 10.6 8 2 4 12 12 12 4 Tetratricopeptide repeat TPR_17 PF13431.1 EMR68438.1 - 2.2e-12 46.1 10.9 0.24 11.6 0.0 11.2 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_10 PF13374.1 EMR68438.1 - 0.00061 19.6 13.0 1.3 9.0 0.0 8.1 9 0 0 9 9 8 1 Tetratricopeptide repeat DUF1762 PF08574.5 EMR68440.1 - 2.4e-08 34.2 12.4 2.4e-08 34.2 8.6 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1762) Pex14_N PF04695.8 EMR68441.1 - 0.0098 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region FAD_binding_4 PF01565.18 EMR68442.1 - 2.7e-15 56.0 0.0 4.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR68442.1 - 0.00013 21.7 0.1 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.9 EMR68442.1 - 0.032 13.8 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Cytokin-bind PF09265.5 EMR68442.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Hydrolase_6 PF13344.1 EMR68445.1 - 3.1e-29 100.8 0.0 5e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR68445.1 - 3.6e-13 50.4 0.0 3.5e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR68445.1 - 1.3e-12 47.2 0.0 7.7e-12 44.7 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EMR68445.1 - 8.6e-08 32.6 0.1 1.3e-05 25.5 0.0 2.4 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HET PF06985.6 EMR68446.1 - 4.2e-18 65.8 0.0 2.7e-17 63.2 0.0 2.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) zf-rbx1 PF12678.2 EMR68447.1 - 0.16 12.0 5.1 0.49 10.5 3.6 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 EMR68447.1 - 0.27 11.0 14.0 1.4 8.8 7.1 3.2 2 1 0 2 2 2 0 Ring finger domain Brix PF04427.13 EMR68448.1 - 6.5e-39 133.5 0.0 9.7e-39 132.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain YdfA_immunity PF12127.3 EMR68448.1 - 0.18 10.6 3.0 0.28 10.0 2.1 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial Nop14 PF04147.7 EMR68448.1 - 0.24 9.2 23.8 0.3 8.9 16.5 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EMR68448.1 - 6.3 5.1 19.6 8.7 4.6 13.6 1.1 1 0 0 1 1 1 0 Daxx Family MFS_1 PF07690.11 EMR68449.1 - 5e-39 134.0 42.8 1.2e-37 129.4 27.2 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily 60KD_IMP PF02096.15 EMR68449.1 - 0.33 10.5 2.5 0.5 9.9 1.0 1.8 2 0 0 2 2 2 0 60Kd inner membrane protein SAYSvFN PF10260.4 EMR68449.1 - 0.79 9.5 3.9 3.2 7.6 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) Pkinase PF00069.20 EMR68450.1 - 2e-71 240.1 0.3 4.3e-71 239.1 0.2 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR68450.1 - 3.6e-54 183.5 0.1 5.9e-54 182.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EMR68450.1 - 4.9e-23 81.3 0.1 1.5e-22 79.7 0.1 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain PH_11 PF15413.1 EMR68450.1 - 2.7e-08 34.0 0.0 8.7e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.1 EMR68450.1 - 8.5e-08 31.4 0.0 1.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMR68450.1 - 0.00049 19.9 0.1 0.0037 17.0 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EMR68450.1 - 0.014 14.2 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PAT1 PF09770.4 EMR68450.1 - 0.97 7.5 18.8 1.5 6.9 13.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EMR68450.1 - 1.1 9.0 12.6 1.7 8.4 8.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 EMR68450.1 - 4.9 6.4 21.2 6.8 5.9 14.7 1.2 1 0 0 1 1 1 0 Vta1 like DND1_DSRM PF14709.1 EMR68451.1 - 0.0053 17.0 0.1 0.25 11.6 0.0 2.5 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 EMR68451.1 - 0.032 14.7 0.2 1.3 9.6 0.0 2.7 2 0 0 2 2 2 0 Double-stranded RNA binding motif Acetyltransf_1 PF00583.19 EMR68452.1 - 8.5e-10 38.5 0.3 1.8e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EMR68452.1 - 5.3e-07 29.5 0.1 1.2e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR68452.1 - 1.2e-06 28.6 0.1 2.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR68452.1 - 2.1e-06 27.8 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EMR68452.1 - 0.00058 19.8 0.1 0.0016 18.3 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR68452.1 - 0.0075 15.9 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EMR68452.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3632 PF12311.3 EMR68453.1 - 8e-28 97.4 1.3 8e-28 97.4 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) TniQ PF06527.6 EMR68454.1 - 0.055 13.6 0.5 0.089 13.0 0.4 1.3 1 0 0 1 1 1 0 TniQ OPT PF03169.10 EMR68455.1 - 1.1e-142 476.7 44.4 2.8e-115 386.1 25.1 2.8 1 1 1 2 2 2 2 OPT oligopeptide transporter protein CcmD PF04995.9 EMR68455.1 - 0.069 12.8 4.4 0.072 12.8 0.4 2.6 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) F-box PF00646.28 EMR68456.1 - 0.0017 17.9 0.1 0.0031 17.1 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMR68456.1 - 0.012 15.3 0.2 0.025 14.3 0.2 1.5 1 0 0 1 1 1 0 F-box-like RNA_pol_I_A49 PF06870.7 EMR68457.1 - 6.5e-76 255.3 0.0 8.6e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DHFR_1 PF00186.14 EMR68458.1 - 2.6e-30 105.1 0.0 6.8e-30 103.7 0.0 1.8 1 1 0 1 1 1 1 Dihydrofolate reductase PhyH PF05721.8 EMR68458.1 - 0.00089 19.3 0.0 0.0035 17.3 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) bZIP_1 PF00170.16 EMR68459.1 - 2.6e-05 24.1 4.5 4.5e-05 23.3 3.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF1013 PF06242.6 EMR68459.1 - 0.24 11.3 1.4 0.44 10.5 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) Complex1_LYR PF05347.10 EMR68461.1 - 3.5e-08 33.1 0.0 1e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMR68461.1 - 1.1e-07 31.9 0.0 3.1e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Complex1_LYR-like UQ_con PF00179.21 EMR68461.1 - 5.1e-06 25.9 0.2 1e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NAM-associated PF14303.1 EMR68461.1 - 0.012 15.9 2.7 0.012 15.9 1.9 1.6 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain DUF605 PF04652.11 EMR68461.1 - 3.2 7.0 9.8 4.6 6.5 6.8 1.2 1 0 0 1 1 1 0 Vta1 like AAA PF00004.24 EMR68462.1 - 2e-14 53.9 0.0 3.9e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMR68462.1 - 0.00013 21.9 0.3 0.001 19.1 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMR68462.1 - 0.00026 21.1 5.3 0.02 15.0 0.0 3.7 3 1 1 4 4 4 1 AAA domain AAA_19 PF13245.1 EMR68462.1 - 0.0012 18.5 0.0 0.0038 16.9 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EMR68462.1 - 0.008 16.9 0.2 0.074 13.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EMR68462.1 - 0.018 14.1 0.0 0.038 13.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EMR68462.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EMR68462.1 - 0.061 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMR68462.1 - 0.085 13.1 0.0 0.58 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EMR68462.1 - 0.086 12.5 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HHH_3 PF12836.2 EMR68462.1 - 0.15 12.0 0.1 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Amidoligase_2 PF12224.3 EMR68464.1 - 0.091 12.3 0.2 1.3 8.6 0.0 2.5 3 0 0 3 3 3 0 Putative amidoligase enzyme 4HBT PF03061.17 EMR68465.1 - 4.5e-12 45.9 0.8 7.5e-12 45.2 0.6 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EMR68465.1 - 0.016 15.2 0.1 0.025 14.5 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) KH_1 PF00013.24 EMR68465.1 - 0.02 14.5 0.1 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 KH domain Aldedh PF00171.17 EMR68466.1 - 2.2e-182 606.5 0.0 2.4e-182 606.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMR68466.1 - 6.3e-05 21.8 0.0 0.0001 21.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EMR68466.1 - 0.029 13.5 0.0 4.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Band_7 PF01145.20 EMR68467.1 - 7.4e-28 97.6 0.4 7.4e-28 97.6 0.3 1.8 3 0 0 3 3 3 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EMR68467.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Aa_trans PF01490.13 EMR68468.1 - 8.6e-32 110.1 35.1 1e-31 109.8 24.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2207 PF09972.4 EMR68468.1 - 4.1 5.8 4.3 12 4.3 3.0 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Amidase PF01425.16 EMR68469.1 - 6.5e-35 120.8 0.4 5.9e-34 117.6 0.8 1.9 2 0 0 2 2 2 1 Amidase HCV_NS1 PF01560.12 EMR68469.1 - 0.16 10.3 0.0 0.27 9.6 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 UQ_con PF00179.21 EMR68470.1 - 1.9e-39 134.2 0.0 2.1e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMR68470.1 - 9.4e-06 25.4 0.0 1.1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMR68470.1 - 0.0094 15.8 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EMR68470.1 - 0.051 13.2 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 UEV domain MAP65_ASE1 PF03999.7 EMR68472.1 - 2.2e-73 247.8 12.7 5.3e-73 246.6 8.0 2.1 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF948 PF06103.6 EMR68472.1 - 0.048 13.5 1.6 0.48 10.3 0.4 3.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 EMR68472.1 - 1.3 8.8 3.9 3.1 7.6 0.9 2.8 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.16 EMR68472.1 - 3.5 7.9 16.8 0.37 11.0 0.8 4.3 3 1 1 4 4 4 0 Spectrin repeat Sybindin PF04099.7 EMR68473.1 - 1.2e-21 76.9 0.0 1.8e-21 76.3 0.0 1.3 1 1 0 1 1 1 1 Sybindin-like family FA_desaturase PF00487.19 EMR68474.1 - 3.9e-05 23.2 4.0 5e-05 22.8 2.8 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Glyco_hydro_cc PF11790.3 EMR68475.1 - 5.1e-27 94.8 0.0 5.8e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PH PF00169.24 EMR68476.1 - 1.1e-09 38.3 0.1 1.6e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EMR68476.1 - 0.0017 18.6 2.5 0.012 15.8 1.7 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 EMR68476.1 - 0.064 13.4 0.1 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Peroxin-3 PF04882.7 EMR68477.1 - 1.9e-130 435.4 0.0 5.6e-130 433.9 0.0 1.8 2 1 0 2 2 2 1 Peroxin-3 EF-hand_4 PF12763.2 EMR68478.1 - 3.6e-05 23.4 0.0 5.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand AAA_12 PF13087.1 EMR68479.1 - 1.9e-26 92.6 0.0 3.2e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMR68479.1 - 1.5e-23 83.5 0.0 3.1e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMR68479.1 - 1.4e-09 37.5 0.1 2e-08 33.8 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EMR68479.1 - 5.9e-06 25.9 0.0 0.0045 16.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMR68479.1 - 0.0012 18.2 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EMR68479.1 - 0.0012 18.6 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.24 EMR68479.1 - 0.0028 17.8 0.0 0.0073 16.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EMR68479.1 - 0.0056 16.2 0.1 0.47 9.9 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EMR68479.1 - 0.0059 16.6 1.3 0.079 12.9 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EMR68479.1 - 0.0078 16.3 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.10 EMR68479.1 - 0.019 13.8 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DEAD PF00270.24 EMR68479.1 - 0.022 14.2 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF2075 PF09848.4 EMR68479.1 - 0.037 13.0 0.8 0.055 12.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 EMR68479.1 - 0.04 13.0 0.0 0.1 11.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.12 EMR68479.1 - 0.044 12.6 0.0 0.076 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RecA PF00154.16 EMR68479.1 - 0.045 12.8 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein SMC_N PF02463.14 EMR68479.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain UvrD_C_2 PF13538.1 EMR68479.1 - 0.11 12.6 0.0 0.73 9.9 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain ATP-synt_ab PF00006.20 EMR68479.1 - 0.23 10.9 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PIF1 PF05970.9 EMR68479.1 - 0.25 10.2 0.0 16 4.3 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase NB-ARC PF00931.17 EMR68479.1 - 0.26 10.1 0.0 0.44 9.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EMR68479.1 - 0.28 11.3 0.0 0.72 10.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase INSIG PF07281.7 EMR68480.1 - 1.4e-39 135.4 2.9 1.1e-38 132.5 2.0 2.3 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) CDC45 PF02724.9 EMR68480.1 - 0.23 9.4 1.9 0.36 8.8 1.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1649 PF07855.7 EMR68481.1 - 1.8e-60 203.3 0.0 2.3e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) efThoc1 PF11957.3 EMR68482.1 - 1.1e-126 423.2 2.8 7.9e-70 235.7 0.1 2.1 1 1 1 2 2 2 2 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 EMR68482.1 - 7.3e-37 126.5 0.0 1.2e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.18 EMR68482.1 - 3.5e-05 23.7 0.0 0.0001 22.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EMR68482.1 - 0.00026 21.3 0.0 0.00074 19.8 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.1 EMR68482.1 - 0.0003 21.0 0.2 0.002 18.4 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EMR68482.1 - 0.001 18.9 0.0 0.0043 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMR68482.1 - 0.0018 17.4 0.0 0.0037 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMR68482.1 - 0.004 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR68482.1 - 0.0061 16.5 0.1 0.027 14.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EMR68482.1 - 0.0068 17.2 0.1 0.032 15.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EMR68482.1 - 0.012 15.9 0.9 0.012 15.9 0.6 2.8 2 1 0 3 3 3 0 AAA domain AAA_29 PF13555.1 EMR68482.1 - 0.021 14.3 0.0 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EMR68482.1 - 0.025 13.7 0.0 0.07 12.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 EMR68482.1 - 0.035 12.9 0.0 0.071 12.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 EMR68482.1 - 0.036 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EMR68482.1 - 0.04 13.3 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EMR68482.1 - 0.045 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 EMR68482.1 - 0.053 13.4 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain CMAS PF02353.15 EMR68483.1 - 1.4e-59 201.4 0.1 1.9e-59 200.9 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EMR68483.1 - 2.8e-11 43.3 0.0 6.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR68483.1 - 2.3e-06 27.9 0.0 4.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR68483.1 - 0.0033 17.9 0.0 0.049 14.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR68483.1 - 0.012 15.9 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EMR68483.1 - 0.066 12.5 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EMR68483.1 - 0.077 13.4 0.2 0.74 10.3 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EMR68483.1 - 0.097 12.2 0.0 0.26 10.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Fork_head PF00250.13 EMR68484.1 - 1.4e-34 118.0 0.5 2.7e-34 117.0 0.3 1.4 1 0 0 1 1 1 1 Fork head domain MAP65_ASE1 PF03999.7 EMR68484.1 - 0.7 8.4 6.0 1.1 7.8 4.1 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) WD40 PF00400.27 EMR68486.1 - 4.7e-12 45.2 0.0 0.00015 21.4 0.0 6.0 6 1 0 6 6 6 3 WD domain, G-beta repeat NmrA PF05368.8 EMR68487.1 - 3e-09 36.5 0.0 3.3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.15 EMR68487.1 - 0.088 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Cellulase PF00150.13 EMR68488.1 - 1.3e-17 63.8 6.0 3.4e-17 62.5 4.1 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HSA PF07529.8 EMR68489.1 - 2.5e-18 65.6 2.8 2.5e-18 65.6 1.9 4.6 4 1 1 5 5 5 2 HSA Myb_DNA-bind_6 PF13921.1 EMR68489.1 - 6.9e-05 22.8 0.5 0.0008 19.4 0.3 2.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain EF-hand_4 PF12763.2 EMR68490.1 - 2.1e-27 94.9 0.0 1.1e-14 53.9 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EMR68490.1 - 0.0002 21.4 0.3 0.13 12.4 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair DUF1720 PF08226.6 EMR68490.1 - 0.0015 18.5 27.6 0.0015 18.5 19.1 8.4 5 3 3 8 8 8 2 Domain of unknown function (DUF1720) EF-hand_6 PF13405.1 EMR68490.1 - 0.0015 18.2 0.0 19 5.4 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EMR68490.1 - 0.0043 16.2 0.0 3.9 7.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EMR68490.1 - 0.058 13.0 0.0 1.4 8.6 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair Glyco_hydro_17 PF00332.13 EMR68491.1 - 0.0051 15.9 0.6 0.0095 15.0 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 EMP70 PF02990.11 EMR68492.1 - 5.8e-146 487.0 1.1 1.4e-145 485.7 0.7 1.6 1 1 0 1 1 1 1 Endomembrane protein 70 DUF3169 PF11368.3 EMR68492.1 - 5.1 6.2 12.0 0.8 8.8 0.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF221 PF02714.10 EMR68493.1 - 1.1e-96 323.5 23.1 1.1e-96 323.5 16.0 1.4 2 0 0 2 2 2 1 Domain of unknown function DUF221 DUF3779 PF12621.3 EMR68493.1 - 1.6e-19 69.5 0.0 6e-19 67.7 0.0 2.0 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EMR68493.1 - 8.6e-10 39.0 10.2 0.00034 21.0 0.1 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4463) RibD_C PF01872.12 EMR68494.1 - 1.2e-21 77.2 0.0 1.9e-20 73.3 0.0 2.3 1 1 0 1 1 1 1 RibD C-terminal domain DUF3720 PF12517.3 EMR68494.1 - 0.79 10.4 4.4 35 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) DUF4066 PF13278.1 EMR68495.1 - 3.3e-26 91.5 0.2 6.7e-22 77.5 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 EMR68495.1 - 0.00048 19.5 0.0 0.00091 18.7 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Hamartin PF04388.7 EMR68496.1 - 8.1e-15 54.5 20.9 6.9e-11 41.5 12.9 2.8 2 1 0 2 2 2 2 Hamartin protein Macoilin PF09726.4 EMR68496.1 - 0.051 11.8 35.3 0.66 8.1 0.6 2.4 1 1 1 2 2 2 0 Transmembrane protein IFP_35_N PF07334.8 EMR68496.1 - 0.31 11.0 0.0 0.31 11.0 0.0 3.2 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FlaC_arch PF05377.6 EMR68496.1 - 0.53 10.2 7.2 34 4.4 0.2 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Ribosomal_L23 PF00276.15 EMR68497.1 - 1.2e-14 54.0 0.0 2.2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Fungal_trans_2 PF11951.3 EMR68498.1 - 2e-22 79.3 0.4 2.7e-22 78.8 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHDPS PF00701.17 EMR68499.1 - 2.8e-31 108.2 0.0 4.1e-31 107.6 0.0 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Hydrolase_like PF13242.1 EMR68499.1 - 0.047 13.3 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like MT-A70 PF05063.9 EMR68500.1 - 1.8e-28 99.2 0.0 2.4e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 EMR68500.1 - 0.0096 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pollen_Ole_e_I PF01190.12 EMR68501.1 - 0.093 12.5 0.1 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Pollen proteins Ole e I like PG_binding_4 PF12229.3 EMR68502.1 - 0.0074 16.5 0.6 1.6 9.0 0.1 2.2 2 0 0 2 2 2 2 Putative peptidoglycan binding domain FIVAR PF07554.8 EMR68502.1 - 8.4 6.7 7.2 3.7 7.8 0.1 2.8 3 1 0 3 3 3 0 Uncharacterised Sugar-binding Domain Metallophos_2 PF12850.2 EMR68503.1 - 0.00014 21.7 0.3 0.0014 18.4 0.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EMR68503.1 - 0.0046 16.3 2.8 0.054 12.8 1.9 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PP-binding PF00550.20 EMR68504.1 - 0.0014 18.8 0.1 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site NIF PF03031.13 EMR68505.1 - 4.1e-52 176.0 0.5 5.3e-52 175.6 0.4 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SET PF00856.23 EMR68507.1 - 4.9e-08 33.4 0.0 1.6e-07 31.8 0.0 1.9 1 1 0 1 1 1 1 SET domain tify PF06200.9 EMR68507.1 - 0.15 11.3 0.1 0.28 10.4 0.1 1.4 1 0 0 1 1 1 0 tify domain TF_Zn_Ribbon PF08271.7 EMR68508.1 - 0.03 13.6 6.9 0.22 10.8 0.1 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 EMR68508.1 - 0.037 13.4 1.2 0.38 10.2 0.1 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-C2H2_4 PF13894.1 EMR68508.1 - 0.038 14.3 7.3 0.18 12.1 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger DUF2225 PF09986.4 EMR68508.1 - 0.09 12.2 0.3 0.28 10.6 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Rubredoxin PF00301.15 EMR68508.1 - 0.22 11.4 1.7 9.7 6.1 0.1 2.9 2 0 0 2 2 2 0 Rubredoxin OrfB_Zn_ribbon PF07282.6 EMR68508.1 - 1.5 8.5 3.9 10 5.8 0.8 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.1 EMR68508.1 - 1.5 9.2 8.8 1.4 9.3 0.2 3.1 2 1 1 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 EMR68508.1 - 2.1 8.8 9.3 7.1 7.1 0.2 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 EMR68508.1 - 4.9 7.3 8.8 4.3 7.5 1.2 3.2 2 2 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF1713 PF08213.6 EMR68510.1 - 9.2e-13 47.5 21.1 9.2e-13 47.5 14.6 1.7 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) RNA_GG_bind PF10258.4 EMR68510.1 - 0.087 12.5 2.2 0.53 10.0 1.0 2.3 2 0 0 2 2 2 0 PHAX RNA-binding domain ABC_membrane_2 PF06472.10 EMR68511.1 - 4.1e-86 288.6 6.9 6.4e-53 179.7 0.1 3.5 3 1 1 4 4 4 2 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EMR68511.1 - 3.2e-16 59.8 0.0 6.5e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EMR68511.1 - 0.067 13.1 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EMR68511.1 - 0.1 12.9 1.4 5.2 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 EMR68512.1 - 0.0002 20.5 0.0 0.00042 19.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain DUF1635 PF07795.6 EMR68512.1 - 0.02 14.2 0.2 0.02 14.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Myb_DNA-bind_5 PF13873.1 EMR68512.1 - 0.024 14.5 0.2 0.17 11.8 0.0 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain BRCT PF00533.21 EMR68513.1 - 0.064 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain zf-C2H2_4 PF13894.1 EMR68514.1 - 0.0055 16.9 6.1 0.033 14.5 1.1 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EMR68514.1 - 0.37 11.2 6.3 0.19 12.1 1.8 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Cation_efflux PF01545.16 EMR68515.1 - 7.6e-76 254.9 9.6 3.1e-75 252.9 6.7 1.8 1 1 0 1 1 1 1 Cation efflux family Glyco_hydro_3_C PF01915.17 EMR68516.1 - 1.1e-73 247.5 0.2 6.3e-72 241.7 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EMR68516.1 - 2.9e-61 207.0 0.0 4.1e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 EMR68516.1 - 1e-23 83.0 0.4 2.9e-23 81.5 0.1 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EMR68516.1 - 2.4e-18 66.1 0.0 4.3e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain ICMT PF04140.9 EMR68517.1 - 6.9e-28 96.7 0.3 1.5e-27 95.5 0.2 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EMR68517.1 - 4.6e-14 52.3 1.1 4.6e-14 52.3 0.7 2.1 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EMR68517.1 - 0.0007 18.9 1.5 0.0007 18.9 1.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) zf-C3HC4_2 PF13923.1 EMR68519.1 - 1.2e-09 38.0 7.9 3.4e-05 23.7 1.6 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMR68519.1 - 1.6e-07 31.0 11.0 2.2e-05 24.1 3.8 2.5 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 EMR68519.1 - 1.5e-06 27.8 10.5 1.5e-05 24.6 3.4 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EMR68519.1 - 1.6e-05 24.5 1.8 4.3e-05 23.1 0.3 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EMR68519.1 - 5e-05 22.8 14.4 0.00019 21.0 4.9 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMR68519.1 - 7e-05 22.3 5.5 0.00043 19.8 0.6 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EMR68519.1 - 0.002 17.9 12.0 0.006 16.4 3.0 2.7 2 0 0 2 2 2 1 FYVE zinc finger Prok-RING_1 PF14446.1 EMR68519.1 - 0.11 12.2 11.9 0.18 11.5 1.5 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 EMR68519.1 - 0.35 10.4 4.3 3.9 7.1 2.6 2.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EMR68519.1 - 0.57 10.1 11.2 0.73 9.7 2.9 3.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.9 EMR68519.1 - 1.7 8.1 8.2 1.9 8.0 0.1 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif Mucin PF01456.12 EMR68519.1 - 6.9 6.4 19.1 1.6 8.5 7.5 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein zinc-ribbons_6 PF07191.7 EMR68519.1 - 8 6.3 10.5 8.2 6.2 0.4 2.9 3 0 0 3 3 3 0 zinc-ribbons Pkinase PF00069.20 EMR68520.1 - 7e-77 258.0 0.0 8e-77 257.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR68520.1 - 8.4e-38 129.9 0.0 1.1e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR68520.1 - 0.0024 16.8 0.1 0.0067 15.4 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EMR68520.1 - 0.037 13.7 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EMR68520.1 - 0.047 12.7 0.1 0.099 11.6 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyltransferase PF01553.16 EMR68521.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Acyltransferase Use1 PF09753.4 EMR68522.1 - 7.4e-11 41.9 0.4 1.4e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Membrane fusion protein Use1 DUF1828 PF08861.5 EMR68522.1 - 0.25 10.9 1.4 4.2 7.0 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF1828 eIF3_subunit PF08597.5 EMR68522.1 - 2.6 7.5 9.5 2 7.9 3.1 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Atg14 PF10186.4 EMR68522.1 - 4.3 6.1 7.8 1.5 7.6 3.5 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Synaptobrevin PF00957.16 EMR68522.1 - 7.4 6.2 6.6 8.5 6.0 0.1 2.8 3 0 0 3 3 3 0 Synaptobrevin PAP_central PF04928.12 EMR68523.1 - 1.4e-99 332.0 0.1 2.4e-99 331.2 0.0 1.4 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EMR68523.1 - 1.3e-39 135.2 0.0 9e-38 129.2 0.0 2.3 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EMR68523.1 - 1.3e-07 31.8 0.0 3.2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DCP2 PF05026.8 EMR68524.1 - 7.4e-34 115.5 1.0 1.4e-33 114.6 0.7 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EMR68524.1 - 1.2e-14 54.0 0.0 2.2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PGK PF00162.14 EMR68525.1 - 3.3e-151 503.2 0.1 3.8e-151 503.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase HET PF06985.6 EMR68526.1 - 6e-29 100.9 0.1 2.2e-28 99.1 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Acyl-CoA_dh_1 PF00441.19 EMR68528.1 - 1.2e-11 44.9 1.3 2.3e-10 40.7 0.9 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMR68528.1 - 1.2e-06 27.8 0.6 2.5e-05 23.6 0.4 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AcylCoA_dehyd_C PF12186.3 EMR68528.1 - 0.06 13.2 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal NACHT PF05729.7 EMR68529.1 - 2.2e-06 27.4 0.0 6.3e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EMR68529.1 - 4.1e-05 23.7 0.6 0.00056 20.0 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EMR68529.1 - 0.00047 20.1 3.5 0.015 15.2 0.0 3.7 3 2 1 4 4 4 1 AAA ATPase domain AAA_10 PF12846.2 EMR68529.1 - 0.005 16.3 6.8 0.0088 15.5 0.2 3.2 3 1 1 4 4 4 1 AAA-like domain Miro PF08477.8 EMR68529.1 - 0.0096 16.4 0.0 0.034 14.6 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein cobW PF02492.14 EMR68529.1 - 0.0098 15.3 0.3 0.056 12.8 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CDH PF02611.10 EMR68529.1 - 0.011 15.0 0.5 0.03 13.5 0.3 1.8 2 0 0 2 2 2 0 CDP-diacylglycerol pyrophosphatase DUF87 PF01935.12 EMR68529.1 - 0.013 15.3 2.1 1.1 9.0 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function DUF87 Arch_ATPase PF01637.13 EMR68529.1 - 0.017 14.8 0.1 0.072 12.7 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 EMR68529.1 - 0.031 14.5 1.4 0.15 12.3 0.0 2.8 3 1 1 4 4 2 0 AAA domain AAA_17 PF13207.1 EMR68529.1 - 0.042 14.6 0.2 0.32 11.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pox_A_type_inc PF04508.7 EMR68529.1 - 0.044 13.5 0.6 0.044 13.5 0.4 2.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat MMR_HSR1 PF01926.18 EMR68529.1 - 0.047 13.6 0.0 0.21 11.5 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 EMR68529.1 - 0.054 13.3 0.3 0.32 10.8 0.2 2.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMR68529.1 - 0.068 13.3 0.1 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EMR68529.1 - 0.094 13.0 0.1 0.094 13.0 0.1 3.1 3 1 0 3 3 3 0 ABC transporter MobB PF03205.9 EMR68529.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DnaJ PF00226.26 EMR68530.1 - 2.7e-06 27.0 0.0 5.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Vpu PF00558.14 EMR68530.1 - 0.0046 16.4 1.2 0.011 15.2 0.9 1.7 1 0 0 1 1 1 1 Vpu protein Glyco_hydro_28 PF00295.12 EMR68531.1 - 9.3e-116 386.3 21.6 1.1e-115 386.1 14.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 TauD PF02668.11 EMR68532.1 - 7.4e-43 147.0 0.1 1e-42 146.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Gram_pos_anchor PF00746.16 EMR68532.1 - 0.47 10.3 2.2 7.9 6.4 0.1 2.5 2 0 0 2 2 2 0 Gram positive anchor ATP_bind_1 PF03029.12 EMR68533.1 - 2e-75 253.3 0.0 2.7e-75 252.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EMR68533.1 - 0.00012 22.1 0.0 0.00037 20.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EMR68533.1 - 0.00019 21.3 0.0 0.00064 19.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMR68533.1 - 0.00021 21.7 0.0 0.15 12.5 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EMR68533.1 - 0.00027 20.4 0.0 0.13 11.7 0.0 3.0 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EMR68533.1 - 0.00098 17.9 0.0 1.2 7.8 0.0 2.3 2 0 0 2 2 2 2 ArgK protein AAA_33 PF13671.1 EMR68533.1 - 0.0011 18.8 0.0 0.0045 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EMR68533.1 - 0.0021 17.5 0.1 0.0043 16.5 0.1 1.7 1 1 0 1 1 1 1 AAA-like domain PRK PF00485.13 EMR68533.1 - 0.0036 16.8 0.0 0.13 11.8 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.13 EMR68533.1 - 0.0051 16.0 0.1 0.098 11.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.1 EMR68533.1 - 0.0058 16.6 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EMR68533.1 - 0.0059 17.4 0.0 0.0059 17.4 0.0 2.6 2 1 0 2 2 1 1 AAA domain NACHT PF05729.7 EMR68533.1 - 0.0063 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EMR68533.1 - 0.0076 15.1 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Arf PF00025.16 EMR68533.1 - 0.011 15.0 0.0 0.89 8.7 0.0 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family G-alpha PF00503.15 EMR68533.1 - 0.012 14.3 0.2 0.81 8.2 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit AAA_30 PF13604.1 EMR68533.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EMR68533.1 - 0.013 14.5 0.2 0.053 12.6 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.17 EMR68533.1 - 0.022 14.2 0.0 0.071 12.5 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.12 EMR68533.1 - 0.033 13.5 0.5 0.65 9.3 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase cobW PF02492.14 EMR68533.1 - 0.036 13.5 0.0 0.54 9.6 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EMR68533.1 - 0.047 13.3 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EMR68533.1 - 0.079 12.4 0.0 0.57 9.6 0.0 2.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EMR68533.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain SGT1 PF07093.6 EMR68533.1 - 0.19 10.0 4.8 0.26 9.6 3.3 1.2 1 0 0 1 1 1 0 SGT1 protein AAA_18 PF13238.1 EMR68533.1 - 0.41 10.9 0.0 0.41 10.9 0.0 2.5 3 0 0 3 3 1 0 AAA domain Daxx PF03344.10 EMR68533.1 - 0.5 8.7 8.6 0.7 8.3 6.0 1.1 1 0 0 1 1 1 0 Daxx Family DUF2346 PF09803.4 EMR68533.1 - 0.54 10.1 3.4 1.3 8.8 2.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) DSS1_SEM1 PF05160.8 EMR68534.1 - 1.2e-25 89.0 11.2 1.6e-25 88.6 7.8 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Cwf_Cwc_15 PF04889.7 EMR68534.1 - 0.23 11.1 7.2 0.27 10.9 5.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mpv17_PMP22 PF04117.7 EMR68535.1 - 2.8e-23 81.3 1.5 4.7e-23 80.6 0.1 2.0 3 0 0 3 3 3 1 Mpv17 / PMP22 family Aldo_ket_red PF00248.16 EMR68537.1 - 2e-51 174.5 0.0 2.4e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3808 PF10300.4 EMR68538.1 - 2.2e-123 412.2 0.0 2.8e-123 411.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_10 PF13374.1 EMR68538.1 - 0.012 15.4 0.0 0.047 13.6 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMR68538.1 - 0.14 12.4 1.3 9.1 6.7 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMR68538.1 - 0.2 12.3 2.3 5.1 8.0 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DNA_RNApol_7kD PF03604.8 EMR68540.1 - 1.2e-15 56.6 8.6 1.6e-15 56.2 6.0 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 EMR68540.1 - 0.0021 17.7 0.6 0.0023 17.6 0.4 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EMR68540.1 - 0.0052 16.5 1.6 0.0072 16.1 1.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon GFA PF04828.9 EMR68540.1 - 0.014 15.3 2.5 2.3 8.2 0.4 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-trcl PF13451.1 EMR68540.1 - 0.035 13.7 2.4 4.7 6.9 0.4 2.2 2 0 0 2 2 2 0 Probable zinc-binding domain A2L_zn_ribbon PF08792.5 EMR68540.1 - 0.045 13.2 3.6 1 8.9 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-C3HC PF07967.8 EMR68540.1 - 0.092 12.5 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like zf-C2H2 PF00096.21 EMR68540.1 - 0.094 13.1 3.7 0.46 10.9 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-dskA_traR PF01258.12 EMR68540.1 - 0.1 12.3 4.1 0.16 11.7 2.9 1.4 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger TFIIS_C PF01096.13 EMR68540.1 - 0.12 12.0 3.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Prok-RING_1 PF14446.1 EMR68540.1 - 0.12 12.0 2.4 0.19 11.4 1.6 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.5 EMR68540.1 - 0.28 11.1 4.9 1.1 9.3 3.4 1.9 1 1 0 1 1 1 0 Zinc ribbon domain DUF2082 PF09855.4 EMR68540.1 - 0.31 10.8 2.6 0.99 9.2 0.4 2.1 1 1 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) TF_Zn_Ribbon PF08271.7 EMR68540.1 - 0.38 10.1 7.5 1.1 8.6 5.2 1.7 1 1 0 1 1 1 0 TFIIB zinc-binding Zn_ribbon_recom PF13408.1 EMR68540.1 - 1.7 8.9 8.5 9 6.6 0.2 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.2 EMR68540.1 - 2.6 7.9 6.5 1.4 8.7 0.8 2.3 2 1 1 3 3 3 0 Transposase zinc-ribbon domain adh_short_C2 PF13561.1 EMR68541.1 - 1.2e-32 113.5 0.0 1.4e-32 113.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR68541.1 - 4.4e-26 91.7 0.6 5.8e-26 91.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68541.1 - 2.4e-10 40.3 0.2 3.3e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 EMR68541.1 - 0.0015 18.3 0.4 0.0021 17.8 0.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.14 EMR68541.1 - 0.0068 15.5 0.5 0.013 14.5 0.3 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain p450 PF00067.17 EMR68542.1 - 7.6e-06 24.7 0.0 8.5e-06 24.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hira PF07569.6 EMR68542.1 - 0.0058 15.8 0.0 0.0069 15.6 0.0 1.1 1 0 0 1 1 1 1 TUP1-like enhancer of split AAA PF00004.24 EMR68543.1 - 9.5e-22 77.6 0.0 2.1e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMR68543.1 - 0.00041 19.4 0.0 0.00082 18.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EMR68543.1 - 0.019 15.7 0.3 1 10.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain TIP49 PF06068.8 EMR68543.1 - 0.049 12.3 0.1 3.5 6.2 0.0 2.3 1 1 1 2 2 2 0 TIP49 C-terminus HIT PF01230.18 EMR68544.1 - 6.7e-17 61.8 0.0 9.9e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EMR68544.1 - 7e-06 26.2 0.0 1.1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2267 PF10025.4 EMR68544.1 - 0.0025 17.8 0.2 0.11 12.5 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2267) CwfJ_C_1 PF04677.10 EMR68544.1 - 0.02 14.5 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 CobT PF06213.7 EMR68544.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT GMC_oxred_N PF00732.14 EMR68545.1 - 7e-52 176.4 0.0 7.7e-51 172.9 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMR68545.1 - 1.2e-05 24.4 0.4 0.0011 17.9 0.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR68545.1 - 0.00099 19.0 0.2 0.0022 17.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMR68545.1 - 0.0025 16.7 0.0 0.0049 15.8 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EMR68545.1 - 0.0031 17.4 0.5 0.014 15.2 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR68545.1 - 0.0096 14.8 0.2 1.6 7.5 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EMR68545.1 - 0.011 15.7 0.1 0.86 9.6 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR68545.1 - 0.014 15.7 0.3 0.75 10.2 0.1 2.8 4 0 0 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR68545.1 - 0.041 12.3 0.2 1.2 7.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 EMR68545.1 - 0.048 12.2 0.2 0.072 11.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EMR68545.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding APH PF01636.18 EMR68547.1 - 3.2e-05 23.7 0.1 5.2e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Beta-lactamase PF00144.19 EMR68549.1 - 1.6e-38 132.5 0.1 8.3e-38 130.2 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase DUF3481 PF11980.3 EMR68550.1 - 0.0044 16.8 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3481) DUF1049 PF06305.6 EMR68550.1 - 0.051 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Pyr_redox_3 PF13738.1 EMR68551.1 - 6.5e-22 78.5 0.0 9.4e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR68551.1 - 1.7e-16 59.5 0.3 2.6e-14 52.3 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMR68551.1 - 1.8e-09 37.0 0.0 1.1e-08 34.4 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMR68551.1 - 7.4e-09 35.7 0.0 1.9e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR68551.1 - 2.2e-08 33.9 0.6 8.8e-07 28.8 0.4 2.9 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR68551.1 - 2.1e-05 23.6 0.2 0.051 12.4 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMR68551.1 - 0.0088 15.8 5.2 5.1 6.8 0.0 4.3 4 1 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EMR68551.1 - 0.011 16.0 0.5 4.7 7.6 0.2 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR68551.1 - 0.024 13.7 0.3 0.068 12.2 0.0 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EMR68551.1 - 0.034 13.0 0.1 0.085 11.6 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 EMR68551.1 - 0.089 12.8 0.1 27 4.8 0.0 3.4 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EMR68551.1 - 0.2 10.0 2.6 0.27 9.6 0.1 2.2 3 0 0 3 3 3 0 HI0933-like protein MFS_1 PF07690.11 EMR68552.1 - 1.3e-33 116.1 25.5 1.8e-27 95.9 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR68552.1 - 5.7e-12 44.9 2.0 5.7e-12 44.9 1.4 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EMR68552.1 - 4.9e-05 21.9 5.2 4.9e-05 21.9 3.6 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 EMR68552.1 - 0.092 10.8 7.3 0.21 9.6 1.1 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector BT1 PF03092.11 EMR68552.1 - 0.19 10.4 9.2 2.4 6.7 6.4 2.4 1 1 0 1 1 1 0 BT1 family AAA PF00004.24 EMR68553.1 - 1.6e-24 86.6 0.0 3.2e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 EMR68553.1 - 2.4e-19 69.6 0.0 4.2e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal RuvB_N PF05496.7 EMR68553.1 - 3.2e-07 29.6 0.0 5.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EMR68553.1 - 0.00013 21.4 0.0 0.0003 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMR68553.1 - 0.00051 20.8 0.0 0.0013 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMR68553.1 - 0.0017 18.1 0.0 0.5 10.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EMR68553.1 - 0.0056 16.1 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EMR68553.1 - 0.0059 15.3 0.0 0.011 14.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EMR68553.1 - 0.0072 16.0 0.1 0.041 13.6 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 EMR68553.1 - 0.018 15.0 0.0 0.044 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain IPT PF01745.11 EMR68553.1 - 0.018 14.1 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase AAA_24 PF13479.1 EMR68553.1 - 0.041 13.4 0.6 0.089 12.3 0.4 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EMR68553.1 - 0.089 12.3 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EMR68553.1 - 0.098 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IncA PF04156.9 EMR68554.1 - 0.00032 20.3 25.0 0.0021 17.6 7.6 6.7 4 2 2 6 6 6 2 IncA protein Filament PF00038.16 EMR68554.1 - 0.0071 15.8 11.3 0.0071 15.8 7.8 6.9 4 2 1 5 5 5 4 Intermediate filament protein TMF_DNA_bd PF12329.3 EMR68554.1 - 0.015 15.0 0.4 0.015 15.0 0.3 10.9 6 4 6 12 12 12 0 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 EMR68554.1 - 0.32 10.1 32.4 0.0086 15.2 1.5 4.9 2 1 4 6 6 6 0 Reovirus sigma C capsid protein DUF2967 PF11179.3 EMR68555.1 - 6 6.2 5.9 0.46 9.9 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) Shisa PF13908.1 EMR68556.1 - 0.002 18.3 0.0 0.0021 18.2 0.0 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.10 EMR68556.1 - 2.8 7.5 6.6 4.5 6.8 4.6 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Vma12 PF11712.3 EMR68556.1 - 6.4 6.4 5.5 2 8.0 1.7 1.6 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pkinase PF00069.20 EMR68559.1 - 5e-22 78.2 0.0 7.7e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EMR68559.1 - 7.1e-16 57.4 3.0 1.4e-09 37.4 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat HEAT PF02985.17 EMR68559.1 - 2.4e-10 39.6 10.1 0.19 11.9 0.1 6.7 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.1 EMR68559.1 - 4.5e-06 26.8 5.0 0.2 11.9 0.1 4.3 3 1 0 3 3 3 2 HEAT repeats Pkinase_Tyr PF07714.12 EMR68559.1 - 4.8e-05 22.5 0.0 7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 EMR68559.1 - 0.023 15.1 7.2 0.45 11.0 0.3 4.4 5 0 0 5 5 5 0 HEAT-like repeat Ribonucleas_3_3 PF14622.1 EMR68561.1 - 6e-07 29.4 0.0 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 EMR68561.1 - 1.1e-05 25.9 0.0 2.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EMR68561.1 - 0.00014 22.2 0.0 0.00053 20.4 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain PLA2_B PF01735.13 EMR68562.1 - 1e-29 103.0 0.0 1.8e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Rotamase_2 PF13145.1 EMR68562.1 - 0.031 14.9 6.1 0.03 14.9 3.2 1.8 1 1 0 1 1 1 0 PPIC-type PPIASE domain Borrelia_P83 PF05262.6 EMR68562.1 - 0.13 10.4 4.7 0.18 10.0 3.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ADH_zinc_N PF00107.21 EMR68563.1 - 5.4e-18 64.7 0.5 9e-18 64.0 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR68563.1 - 9.4e-09 36.2 0.7 2.9e-08 34.6 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase SH3_9 PF14604.1 EMR68564.1 - 1.8e-07 30.6 0.1 3.7e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF1183 PF06682.7 EMR68564.1 - 2.5e-05 24.0 0.8 4.7e-05 23.1 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) SH3_1 PF00018.23 EMR68564.1 - 0.00021 20.6 0.1 0.00043 19.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Glycophorin_A PF01102.13 EMR68564.1 - 0.0042 16.8 0.0 0.014 15.1 0.0 1.9 1 0 0 1 1 1 1 Glycophorin A TMEM51 PF15345.1 EMR68564.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.1 EMR68564.1 - 0.17 12.3 0.0 0.48 10.8 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Lamp PF01299.12 EMR68564.1 - 9.2 5.3 9.7 9.3 5.2 0.6 2.3 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Lactamase_B PF00753.22 EMR68565.1 - 6.4e-12 45.5 0.1 7.4e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMR68565.1 - 3.1e-05 23.6 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DAO PF01266.19 EMR68566.1 - 4.7e-17 61.9 3.8 7.3e-17 61.3 2.6 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase PhyH PF05721.8 EMR68569.1 - 7.6e-06 26.1 0.0 2.8e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Prim_Zn_Ribbon PF08273.7 EMR68569.1 - 0.2 11.7 2.2 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase adh_short PF00106.20 EMR68570.1 - 2.6e-28 99.0 0.1 3.9e-28 98.4 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68570.1 - 7.4e-15 55.0 0.0 1.1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR68570.1 - 4.7e-07 29.8 0.0 6.6e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR68570.1 - 2.8e-05 23.6 0.0 4.7e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMR68570.1 - 0.0019 17.9 1.2 0.0029 17.3 0.2 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EMR68570.1 - 0.0083 15.0 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EMR68570.1 - 0.028 14.5 0.5 0.071 13.2 0.2 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3458 PF11940.3 EMR68570.1 - 0.043 12.6 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) ThiF PF00899.16 EMR68570.1 - 0.067 13.0 0.3 0.42 10.4 0.2 2.0 1 1 1 2 2 2 0 ThiF family Val_tRNA-synt_C PF10458.4 EMR68572.1 - 0.0058 16.6 0.0 0.0094 16.0 0.0 1.3 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm HrpB7 PF09486.5 EMR68573.1 - 0.018 14.9 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Mpv17_PMP22 PF04117.7 EMR68574.1 - 2.8e-18 65.3 0.2 2.8e-18 65.3 0.2 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family Ank_2 PF12796.2 EMR68575.1 - 1.1e-45 153.8 22.7 2.2e-08 34.3 0.0 11.0 5 5 5 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 EMR68575.1 - 9.3e-24 82.0 31.0 3.7e-05 23.3 0.0 17.4 19 0 0 19 19 19 9 Ankyrin repeat Ank_5 PF13857.1 EMR68575.1 - 1.6e-16 59.9 15.1 8e-06 25.9 0.0 8.9 10 1 1 11 11 11 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR68575.1 - 2.5e-15 55.0 14.1 0.025 14.7 0.0 15.3 16 0 0 16 16 16 2 Ankyrin repeat Ank_4 PF13637.1 EMR68575.1 - 1.2e-14 54.3 9.3 0.0015 19.0 0.0 10.2 8 3 2 10 10 10 3 Ankyrin repeats (many copies) DUF3384 PF11864.3 EMR68575.1 - 0.035 12.5 0.0 0.081 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) UDPGT PF00201.13 EMR68577.1 - 1.3e-07 30.5 0.1 1.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EMR68577.1 - 3.6e-05 23.4 0.0 5.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.15 EMR68577.1 - 0.00053 19.7 0.6 0.0013 18.5 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_1_3 PF13528.1 EMR68577.1 - 0.046 12.9 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Glyco_hydro_61 PF03443.9 EMR68578.1 - 3.1e-57 193.9 0.1 3.6e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PLA2_B PF01735.13 EMR68578.1 - 0.03 12.4 0.1 0.042 12.0 0.0 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain zf-MYND PF01753.13 EMR68579.1 - 9e-10 38.2 10.5 9e-10 38.2 7.3 1.7 2 0 0 2 2 2 1 MYND finger Ecl1 PF12855.2 EMR68579.1 - 0.59 9.4 5.5 1.2 8.4 3.8 1.6 1 1 0 1 1 1 0 Life-span regulatory factor FAD_binding_3 PF01494.14 EMR68580.1 - 8.6e-23 80.9 0.0 1.5e-22 80.1 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR68580.1 - 8e-09 34.8 1.5 0.00059 18.8 0.1 2.6 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR68580.1 - 9.9e-08 32.2 0.2 4.6e-05 23.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR68580.1 - 4.9e-05 23.2 0.1 0.0001 22.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMR68580.1 - 0.0009 18.1 0.3 0.0057 15.5 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EMR68580.1 - 0.0022 18.0 0.2 0.016 15.2 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR68580.1 - 0.0022 17.8 0.4 0.004 17.0 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR68580.1 - 0.0073 15.2 0.1 0.55 9.0 0.1 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.9 EMR68580.1 - 0.014 13.9 0.7 0.29 9.5 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 EMR68580.1 - 0.11 11.3 0.3 0.18 10.5 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EMR68580.1 - 0.24 10.0 1.0 2.6 6.5 0.1 2.8 4 0 0 4 4 4 0 Tryptophan halogenase Esterase_phd PF10503.4 EMR68581.1 - 8.4e-06 25.1 0.1 1.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EMR68581.1 - 3e-05 23.3 0.1 0.00032 19.9 0.1 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMR68581.1 - 0.00014 21.6 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR68581.1 - 0.025 14.4 0.1 0.049 13.5 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Transferase PF02458.10 EMR68582.1 - 2.3e-22 79.0 0.0 3.1e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Transferase family Amidohydro_2 PF04909.9 EMR68583.1 - 1.4e-13 51.0 0.0 1.8e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 EMR68584.1 - 2.8e-28 98.6 30.7 5.4e-20 71.4 7.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1298 PF06974.8 EMR68584.1 - 0.094 12.5 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) CMV_1a PF12467.3 EMR68585.1 - 1.2 9.4 3.8 1.5 9.1 2.6 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family NAD_binding_10 PF13460.1 EMR68586.1 - 1.1e-19 71.1 0.2 1.6e-16 60.8 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR68586.1 - 4.6e-05 22.7 0.0 6.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.12 EMR68586.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Dioxygenase_C PF00775.16 EMR68587.1 - 0.00018 20.8 1.4 0.00062 19.0 0.9 1.8 1 1 0 1 1 1 1 Dioxygenase Methyltransf_18 PF12847.2 EMR68588.1 - 3.1e-09 37.3 0.0 4.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR68588.1 - 5.7e-09 36.2 0.0 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR68588.1 - 1.9e-08 34.6 0.0 3.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR68588.1 - 2e-07 31.4 0.0 5.5e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR68588.1 - 1.8e-06 27.7 0.0 2.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR68588.1 - 3.6e-05 23.7 0.0 6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR68588.1 - 5.2e-05 22.8 0.0 7.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMR68588.1 - 0.00054 19.1 0.0 0.0007 18.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EMR68588.1 - 0.00064 19.1 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EMR68588.1 - 0.00092 18.3 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.7 EMR68588.1 - 0.0012 18.1 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Pyr_redox_3 PF13738.1 EMR68589.1 - 1.8e-24 86.9 0.0 1.4e-23 84.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR68589.1 - 2.7e-14 52.2 0.0 3.1e-08 32.3 0.0 2.4 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMR68589.1 - 8.3e-07 28.2 0.0 4e-06 25.9 0.0 2.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMR68589.1 - 1.4e-06 28.1 0.1 0.003 17.3 0.1 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMR68589.1 - 8.3e-06 25.8 0.0 3.4e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR68589.1 - 1.2e-05 24.4 0.1 0.02 14.0 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 EMR68589.1 - 7e-05 22.7 0.0 0.00035 20.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EMR68589.1 - 0.00045 18.8 0.0 0.23 9.9 0.0 2.7 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.22 EMR68589.1 - 0.0057 17.0 0.1 9 6.7 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR68589.1 - 0.0096 14.8 0.1 4 6.2 0.0 2.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 EMR68589.1 - 0.26 10.1 0.1 1.3 7.7 0.0 2.2 3 0 0 3 3 3 0 Glucose inhibited division protein A AA_permease PF00324.16 EMR68590.1 - 3.4e-123 411.5 40.3 3.8e-123 411.3 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR68590.1 - 2.9e-37 128.2 47.8 3.6e-37 127.9 33.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2192 PF09958.4 EMR68590.1 - 0.22 10.7 0.0 3.2 6.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2192) DEC-1_N PF04625.8 EMR68591.1 - 7.2 5.1 19.6 9.2 4.8 13.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ketoacyl-synt PF00109.21 EMR68593.1 - 1.3e-72 244.3 0.0 2.6e-72 243.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EMR68593.1 - 1e-59 202.1 0.2 1.7e-59 201.4 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EMR68593.1 - 1.8e-59 200.4 6.0 2.1e-59 200.2 1.1 3.0 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 EMR68593.1 - 5.7e-53 180.3 0.0 9.5e-53 179.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EMR68593.1 - 4.1e-48 163.4 1.0 4.1e-48 163.4 0.7 3.0 4 0 0 4 4 4 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMR68593.1 - 1.4e-31 108.8 1.5 3.5e-31 107.5 0.1 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EMR68593.1 - 6.9e-06 25.2 0.2 1.3e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EMR68593.1 - 0.0038 16.8 1.4 0.12 12.0 0.2 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PP-binding PF00550.20 EMR68593.1 - 0.0057 16.8 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Acetyltransf_1 PF00583.19 EMR68595.1 - 5.6e-06 26.2 0.4 8e-06 25.7 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMR68595.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 EMR68595.1 - 0.016 15.3 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR68595.1 - 0.075 13.1 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SET PF00856.23 EMR68597.1 - 1.6e-11 44.7 0.0 6e-11 42.9 0.0 1.9 1 1 0 1 1 1 1 SET domain CRC_subunit PF08624.5 EMR68598.1 - 1.5e-58 196.6 0.3 2.4e-58 195.9 0.0 1.5 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF4611 PF15387.1 EMR68598.1 - 7.9 6.7 12.4 63 3.8 7.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Acetyltransf_7 PF13508.1 EMR68599.1 - 0.0011 19.0 0.0 0.025 14.7 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR68599.1 - 0.0031 17.4 0.4 0.039 13.9 0.0 2.7 2 1 1 3 3 3 1 Acetyltransferase (GNAT) family Ank_5 PF13857.1 EMR68599.1 - 0.0091 16.2 0.0 0.46 10.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMR68599.1 - 0.014 15.7 0.0 0.054 13.8 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.25 EMR68599.1 - 0.077 12.8 0.0 5.3 7.0 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeat AAA PF00004.24 EMR68600.1 - 1.4e-17 64.1 0.0 2.5e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.7 EMR68600.1 - 0.0027 17.1 0.1 0.059 12.8 0.1 2.4 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EMR68600.1 - 0.0039 17.3 0.0 0.022 14.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EMR68600.1 - 0.0064 16.4 0.3 0.033 14.1 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EMR68600.1 - 0.029 15.1 1.6 0.38 11.5 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.1 EMR68600.1 - 0.096 12.4 0.3 0.26 11.0 0.2 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EMR68600.1 - 0.11 12.2 0.0 0.89 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PhoPQ_related PF10142.4 EMR68601.1 - 0.0039 15.7 0.0 0.0053 15.2 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Glyco_hydro_3 PF00933.16 EMR68602.1 - 2.8e-94 315.4 0.0 5e-94 314.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR68602.1 - 3.2e-58 196.9 0.4 1.4e-57 194.8 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR68602.1 - 2.1e-16 59.5 0.0 4.2e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF2528 PF10800.3 EMR68602.1 - 0.088 13.2 0.1 3.1 8.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2528) DUF3237 PF11578.3 EMR68603.1 - 7.4e-20 70.7 0.0 7.9e-20 70.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-RING_2 PF13639.1 EMR68607.1 - 1.9e-08 34.0 0.2 3.5e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMR68607.1 - 4.4e-08 33.1 0.1 9.2e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EMR68607.1 - 3e-06 26.8 0.4 8.4e-06 25.4 0.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EMR68607.1 - 0.00015 21.3 0.1 0.0003 20.3 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMR68607.1 - 0.00092 19.1 0.4 0.0039 17.1 0.3 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMR68607.1 - 0.0017 18.1 0.1 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EMR68607.1 - 0.0075 15.9 0.0 0.018 14.7 0.0 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMR68607.1 - 0.027 14.3 0.0 0.073 12.9 0.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EMR68607.1 - 0.029 14.3 0.3 0.055 13.4 0.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 EMR68607.1 - 0.039 13.6 1.4 0.24 11.1 1.1 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Hce2 PF14856.1 EMR68608.1 - 1.6e-08 34.3 0.1 1.9e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor OPT PF03169.10 EMR68609.1 - 5.3e-151 504.1 53.1 6.1e-151 503.9 36.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein E1-E2_ATPase PF00122.15 EMR68609.1 - 0.26 10.2 1.3 0.71 8.8 0.9 1.7 1 0 0 1 1 1 0 E1-E2 ATPase PhoD PF09423.5 EMR68610.1 - 5.3e-62 209.8 0.0 6.4e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Peptidase_S10 PF00450.17 EMR68612.1 - 3.3e-97 326.2 0.1 3.9e-97 326.0 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase GMC_oxred_N PF00732.14 EMR68613.1 - 6e-35 120.8 0.0 1.1e-33 116.6 0.0 2.1 1 1 1 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR68613.1 - 4.1e-27 95.2 0.1 8.9e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EMR68613.1 - 0.0023 16.9 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EMR68613.1 - 0.0036 16.2 0.6 0.53 9.0 0.7 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EMR68613.1 - 0.0057 16.5 0.0 0.043 13.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR68613.1 - 0.0082 16.1 0.3 0.018 15.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMR68613.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EMR68613.1 - 0.24 9.8 0.1 0.37 9.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Ank_2 PF12796.2 EMR68614.1 - 1.2e-82 272.3 13.1 9.7e-18 64.3 0.6 7.4 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 EMR68614.1 - 8.8e-65 211.4 20.5 1.7e-09 36.9 0.0 14.8 16 0 0 16 16 16 12 Ankyrin repeat Ank_4 PF13637.1 EMR68614.1 - 1.7e-49 165.3 12.5 5.7e-08 33.0 0.0 11.3 5 4 8 14 14 14 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR68614.1 - 2.8e-48 160.8 18.0 3.6e-10 39.7 0.1 10.9 7 3 4 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR68614.1 - 1.6e-41 136.1 19.2 4e-06 26.5 0.0 14.4 15 0 0 15 15 15 10 Ankyrin repeat Abhydrolase_3 PF07859.8 EMR68615.1 - 2e-06 27.5 1.1 0.0015 18.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR68615.1 - 3.4e-06 27.1 8.1 6.2e-06 26.2 5.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR68615.1 - 0.00079 19.2 1.7 0.0014 18.3 1.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EMR68615.1 - 0.0097 16.1 0.4 0.015 15.5 0.3 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF3089 PF11288.3 EMR68615.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF2974 PF11187.3 EMR68615.1 - 0.11 11.9 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SKIP_SNW PF02731.10 EMR68617.1 - 1.1e-66 223.1 7.4 1.1e-66 223.1 5.1 2.8 2 0 0 2 2 2 1 SKIP/SNW domain EMP24_GP25L PF01105.19 EMR68617.1 - 3e-45 154.2 2.3 6.8e-45 153.0 1.6 1.6 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4603 PF15376.1 EMR68617.1 - 0.011 12.9 18.1 0.017 12.3 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Abhydrolase_6 PF12697.2 EMR68618.1 - 8.4e-14 51.9 0.1 1.1e-13 51.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR68618.1 - 5.1e-13 48.9 0.0 7.7e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EMR68618.1 - 5.1e-09 35.9 0.0 8.1e-09 35.2 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EMR68618.1 - 2.6e-08 32.7 0.0 0.0015 17.1 0.0 3.0 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EMR68618.1 - 2.7e-08 33.3 0.0 1.3e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EMR68618.1 - 0.00019 21.2 0.0 0.0035 17.0 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 EMR68618.1 - 0.0053 16.2 0.0 0.024 14.0 0.0 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 EMR68618.1 - 0.12 11.8 0.0 0.57 9.6 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMR68618.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase RCR PF12273.3 EMR68619.1 - 0.0023 18.5 3.2 0.0023 18.5 2.2 2.1 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.5 EMR68619.1 - 0.0037 16.5 0.1 0.009 15.3 0.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Sigma70_ner PF04546.8 EMR68619.1 - 0.011 15.3 1.8 0.019 14.5 1.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Syndecan PF01034.15 EMR68619.1 - 0.11 12.1 0.1 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Nucleoplasmin PF03066.10 EMR68619.1 - 6.5 6.2 6.4 13 5.2 4.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin Mito_carr PF00153.22 EMR68621.1 - 2.9e-74 244.8 0.7 6.7e-25 86.6 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EMR68621.1 - 4.4e-14 50.6 4.8 6e-07 28.3 0.1 5.9 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 EMR68621.1 - 1.5e-13 50.6 3.6 5.1e-07 29.7 0.9 4.3 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 EMR68621.1 - 1.2e-12 46.5 1.0 1.8e-06 27.3 0.1 5.5 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.1 EMR68621.1 - 7e-10 38.3 5.2 0.039 13.5 0.0 6.2 6 2 1 7 7 7 4 EF-hand domain pair EF-hand_5 PF13202.1 EMR68621.1 - 8.5e-07 28.0 5.0 8.5e-05 21.7 0.2 4.0 5 0 0 5 5 5 1 EF hand NmrA PF05368.8 EMR68622.1 - 5.3e-15 55.3 0.0 6.8e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR68622.1 - 6.6e-14 52.3 0.2 1.1e-13 51.6 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EMR68622.1 - 1.6e-07 30.6 0.2 2.3e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EMR68622.1 - 0.0001 22.5 0.1 0.00019 21.7 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EMR68622.1 - 0.00017 21.1 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EMR68622.1 - 0.0009 19.1 0.3 0.0024 17.7 0.1 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 EMR68622.1 - 0.0038 15.9 0.1 0.0056 15.4 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EMR68622.1 - 0.0065 16.8 0.3 0.014 15.8 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.7 EMR68622.1 - 0.0084 15.0 0.2 0.015 14.2 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EMR68622.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.15 EMR68622.1 - 0.035 14.1 0.1 0.054 13.5 0.1 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KR PF08659.5 EMR68622.1 - 0.073 12.7 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 EMR68622.1 - 0.083 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CoA_binding PF02629.14 EMR68622.1 - 0.16 12.5 0.9 0.37 11.3 0.3 1.8 2 0 0 2 2 1 0 CoA binding domain Sugar_tr PF00083.19 EMR68624.1 - 4.8e-74 249.5 23.4 5.6e-74 249.3 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR68624.1 - 5.8e-22 77.8 35.6 6.1e-18 64.6 17.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HMG_box PF00505.14 EMR68625.1 - 0.019 15.2 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box F-box PF00646.28 EMR68626.1 - 0.036 13.7 0.1 0.084 12.5 0.1 1.6 1 0 0 1 1 1 0 F-box domain UPF0075 PF03702.9 EMR68627.1 - 5.6e-84 282.1 0.0 6.6e-84 281.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) FMN_red PF03358.10 EMR68628.1 - 1.3e-21 76.7 0.0 1.8e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EMR68628.1 - 2.1e-05 24.1 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold WD40 PF00400.27 EMR68629.1 - 0.0015 18.3 0.4 0.64 10.0 0.1 3.6 3 1 0 3 3 3 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EMR68629.1 - 0.14 10.9 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Vps39_1 PF10366.4 EMR68630.1 - 2.1e-29 101.6 0.0 1e-21 76.9 0.0 3.9 3 0 0 3 3 3 2 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 EMR68630.1 - 3.2e-17 62.8 0.0 8.4e-17 61.4 0.0 1.6 1 1 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 EMR68630.1 - 5.7e-12 45.7 0.1 2e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 TPR_16 PF13432.1 EMR68630.1 - 0.00025 21.6 2.6 0.3 11.8 0.0 4.2 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR68630.1 - 0.00028 21.1 0.1 1.1 9.6 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMR68630.1 - 0.0015 18.0 3.6 5.9 6.6 0.9 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMR68630.1 - 0.0016 18.1 0.9 51 4.1 0.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMR68630.1 - 0.0045 16.6 0.5 7 6.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMR68630.1 - 0.0076 16.1 2.5 37 4.3 0.0 5.1 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMR68630.1 - 0.023 14.3 1.2 12 5.6 0.4 4.1 3 1 1 4 4 4 0 TPR repeat TPR_14 PF13428.1 EMR68630.1 - 0.21 12.3 3.9 46 5.0 0.0 5.2 5 1 1 6 6 4 0 Tetratricopeptide repeat Amidohydro_4 PF13147.1 EMR68631.1 - 5.6e-09 36.4 5.3 0.00017 21.7 0.1 3.3 3 2 0 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 EMR68631.1 - 3.2e-08 33.2 0.2 3.2e-08 33.2 0.1 4.1 4 1 1 5 5 5 1 Amidohydrolase Amidohydro_1 PF01979.15 EMR68631.1 - 1.3e-07 31.6 7.0 1.1e-06 28.6 1.8 3.4 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.6 EMR68631.1 - 1.4e-05 24.5 1.4 0.011 15.0 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family NAD_binding_2 PF03446.10 EMR68633.1 - 5.5e-25 88.0 1.1 9.6e-25 87.3 0.8 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMR68633.1 - 4.5e-24 84.8 0.2 1.1e-22 80.3 0.0 2.3 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Lactamase_B_2 PF12706.2 EMR68633.1 - 6.1e-05 22.6 0.1 0.00021 20.9 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMR68633.1 - 7.1e-05 22.5 3.2 0.00026 20.7 2.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EMR68633.1 - 0.05 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain CMD PF02627.15 EMR68634.1 - 1e-19 70.1 0.1 1.9e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family PPTA PF01239.17 EMR68635.1 - 2.5e-37 124.6 13.3 2.2e-09 36.2 0.7 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Mucin PF01456.12 EMR68635.1 - 0.53 10.0 14.7 0.84 9.4 10.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Ank_2 PF12796.2 EMR68636.1 - 1.7e-19 69.9 0.0 5.1e-13 49.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMR68636.1 - 9.1e-12 45.1 0.0 5.4e-05 23.5 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EMR68636.1 - 2.7e-11 42.6 0.1 0.00038 20.1 0.0 5.2 5 1 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EMR68636.1 - 9.5e-09 35.2 0.1 6.3e-07 29.4 0.0 3.4 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR68636.1 - 6.7e-08 32.0 0.1 0.13 12.6 0.0 5.4 5 1 1 6 6 6 2 Ankyrin repeat SPX PF03105.14 EMR68637.1 - 5.5e-48 164.1 0.0 1.1e-47 163.1 0.0 1.5 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EMR68637.1 - 1.4e-34 119.7 33.8 2.1e-34 119.2 23.4 1.3 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EMR68637.1 - 2.3e-16 59.3 44.2 7e-13 47.8 19.2 2.8 1 1 2 3 3 3 3 Citrate transporter PBP1_TM PF14812.1 EMR68637.1 - 0.0023 18.1 7.2 0.0048 17.1 0.9 2.6 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal FTA2 PF13095.1 EMR68637.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 MFS_1 PF07690.11 EMR68638.1 - 4.2e-27 94.7 32.4 5.2e-27 94.4 21.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 EMR68638.1 - 0.028 14.8 0.8 0.028 14.8 0.5 2.1 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) NmrA PF05368.8 EMR68639.1 - 1.1e-29 103.4 0.2 2.4e-29 102.2 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR68639.1 - 1.1e-11 45.0 0.3 4.9e-11 42.9 0.2 1.9 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EMR68639.1 - 7.1e-05 23.0 0.4 0.00014 22.1 0.3 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EMR68639.1 - 0.0028 17.5 0.7 0.0057 16.5 0.5 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 EMR68639.1 - 0.011 14.4 0.1 0.016 13.8 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MCR_beta_N PF02783.10 EMR68639.1 - 0.023 14.1 1.2 3.5 7.0 0.1 2.9 3 0 0 3 3 3 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain NAD_binding_4 PF07993.7 EMR68639.1 - 0.034 13.0 0.1 0.055 12.3 0.1 1.3 1 0 0 1 1 1 0 Male sterility protein Epimerase PF01370.16 EMR68639.1 - 0.038 13.4 0.1 0.071 12.5 0.1 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_M20 PF01546.23 EMR68640.1 - 5.9e-21 74.8 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMR68640.1 - 5.7e-05 22.8 0.0 0.00015 21.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMR68640.1 - 0.0042 16.8 0.0 0.0076 15.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 CesT PF05932.8 EMR68640.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family RNase_H PF00075.19 EMR68641.1 - 1.3e-16 61.1 0.0 2.7e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 RNase H TauD PF02668.11 EMR68641.1 - 0.033 13.8 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family HbrB PF08539.6 EMR68643.1 - 5.4e-50 169.3 0.0 1.2e-49 168.1 0.0 1.6 1 0 0 1 1 1 1 HbrB-like Activator_LAG-3 PF11498.3 EMR68643.1 - 0.3 9.7 31.8 0.64 8.7 22.1 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.5 EMR68643.1 - 0.71 7.9 44.5 0.083 11.0 23.5 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal ABC_tran PF00005.22 EMR68644.1 - 2.6e-29 102.2 0.1 4.4e-29 101.5 0.1 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EMR68644.1 - 2.2e-06 27.0 1.5 0.00019 20.7 0.1 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 EMR68644.1 - 3.7e-05 23.3 0.0 7.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF87 PF01935.12 EMR68644.1 - 7.9e-05 22.5 0.6 0.00016 21.5 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EMR68644.1 - 0.0011 19.0 0.5 0.011 15.9 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMR68644.1 - 0.0027 18.5 0.0 0.0059 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMR68644.1 - 0.0038 17.5 0.0 0.0072 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EMR68644.1 - 0.0047 16.8 0.2 0.0096 15.8 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Sigma54_activ_2 PF14532.1 EMR68644.1 - 0.0056 16.7 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_21 PF13304.1 EMR68644.1 - 0.0057 16.6 0.0 2.4 8.0 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 EMR68644.1 - 0.0066 15.9 0.4 0.061 12.7 0.1 2.0 1 1 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EMR68644.1 - 0.0089 16.0 0.6 0.022 14.7 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EMR68644.1 - 0.0095 15.4 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 EMR68644.1 - 0.01 15.5 0.2 0.028 14.1 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EMR68644.1 - 0.026 13.9 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EMR68644.1 - 0.042 13.3 0.0 0.094 12.1 0.0 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_33 PF13671.1 EMR68644.1 - 0.042 13.7 0.5 0.17 11.7 0.3 2.1 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EMR68644.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 EMR68644.1 - 0.091 12.3 0.2 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EMR68644.1 - 0.11 12.7 0.4 1.1 9.4 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EMR68644.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EMR68644.1 - 0.25 10.1 1.0 0.47 9.2 0.1 1.9 3 0 0 3 3 3 0 NB-ARC domain Atg8 PF02991.11 EMR68645.1 - 2.7e-51 171.8 0.2 3.2e-51 171.6 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EMR68645.1 - 2.7e-06 27.4 0.0 3.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Pkinase PF00069.20 EMR68646.1 - 0.00048 19.3 0.0 0.21 10.6 0.0 2.9 2 2 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR68646.1 - 0.017 14.2 0.0 1 8.3 0.0 3.0 3 1 1 4 4 4 0 Protein tyrosine kinase MFS_1 PF07690.11 EMR68648.1 - 1.5e-16 60.0 18.3 5.5e-10 38.4 3.6 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily RseC_MucC PF04246.7 EMR68648.1 - 0.0032 17.0 1.4 2.3 7.7 0.0 2.8 2 1 0 2 2 2 2 Positive regulator of sigma(E), RseC/MucC DUF2109 PF09882.4 EMR68648.1 - 0.095 12.6 1.5 0.23 11.4 1.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) LIM_bind PF01803.11 EMR68649.1 - 8e-61 205.1 0.8 8e-61 205.1 0.5 3.3 1 1 2 3 3 3 1 LIM-domain binding protein HCV_NS5a_1b PF08301.8 EMR68650.1 - 0.14 12.5 0.3 3.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a domain 1b Gon7 PF08738.5 EMR68651.1 - 4.5e-12 45.8 2.4 1.4e-11 44.3 0.1 2.3 2 1 0 2 2 2 1 Gon7 family ADH_N PF08240.7 EMR68652.1 - 8.6e-18 64.0 0.3 3.7e-17 62.0 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR68652.1 - 9.7e-17 60.7 0.6 1.6e-16 59.9 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EMR68652.1 - 0.012 16.1 0.3 0.025 15.1 0.2 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EMR68652.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain NAD_binding_11 PF14833.1 EMR68653.1 - 4.3e-23 81.6 0.1 7.2e-23 80.9 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EMR68653.1 - 4.6e-22 78.6 0.0 6.1e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_2 PF00891.13 EMR68654.1 - 1.9e-32 112.3 0.0 2.8e-32 111.8 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EMR68654.1 - 0.00028 20.6 0.0 0.00052 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ish1 PF10281.4 EMR68654.1 - 0.17 11.9 0.3 34 4.6 0.0 3.4 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein DEC-1_N PF04625.8 EMR68655.1 - 0.0063 15.2 6.0 0.0076 14.9 4.1 1.1 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region CMD PF02627.15 EMR68656.1 - 2.3e-06 27.3 0.0 4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family MAF_flag10 PF01973.13 EMR68656.1 - 0.055 12.9 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF115 Caps_synth PF05704.7 EMR68657.1 - 1.8e-11 43.7 0.0 2.5e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EMR68657.1 - 3.7e-07 30.4 0.0 6.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMR68657.1 - 0.14 10.6 0.3 0.19 10.1 0.2 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DEAD PF00270.24 EMR68658.1 - 7.7e-21 74.3 0.0 3.7e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR68658.1 - 4.8e-19 68.0 0.1 5.4e-18 64.6 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMR68658.1 - 1.8e-05 23.6 0.0 2.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EMR68658.1 - 0.00063 19.6 0.0 0.0019 18.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EMR68658.1 - 0.04 13.4 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.1 EMR68658.1 - 0.083 12.8 0.0 0.39 10.6 0.0 2.1 1 1 1 2 2 2 0 Helicase C-terminal domain GRP PF07172.6 EMR68658.1 - 5.4 7.5 14.4 14 6.1 10.0 1.7 1 0 0 1 1 1 0 Glycine rich protein family ECH PF00378.15 EMR68659.1 - 4.7e-27 94.6 0.1 3.9e-26 91.6 0.1 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Serglycin PF04360.7 EMR68659.1 - 0.084 12.6 1.9 0.17 11.6 1.3 1.5 1 0 0 1 1 1 0 Serglycin Methyltransf_23 PF13489.1 EMR68660.1 - 4.6e-20 71.9 0.0 8.4e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR68660.1 - 1.4e-09 38.2 0.0 3.8e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR68660.1 - 5e-09 36.7 0.0 1.8e-07 31.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR68660.1 - 8.4e-09 35.1 0.0 2.2e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR68660.1 - 4.6e-08 33.4 0.0 1.1e-06 29.0 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR68660.1 - 5e-05 22.5 0.0 0.031 13.3 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMR68660.1 - 0.0014 18.9 0.0 0.0057 16.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR68660.1 - 0.0021 18.0 0.1 0.048 13.7 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 EMR68660.1 - 0.0039 16.6 0.0 0.006 16.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EMR68660.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EMR68660.1 - 0.024 14.0 0.0 0.089 12.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EMR68660.1 - 0.028 13.4 0.0 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase CMAS PF02353.15 EMR68660.1 - 0.051 12.6 0.0 0.28 10.2 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EMR68660.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Vps51 PF08700.6 EMR68661.1 - 9.9e-16 57.3 0.0 5e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 Vps51/Vps67 TraH_2 PF06871.6 EMR68661.1 - 0.12 11.8 0.4 0.21 11.0 0.3 1.3 1 0 0 1 1 1 0 TraH_2 PP2C PF00481.16 EMR68662.1 - 2.8e-30 105.5 0.0 1.5e-29 103.2 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMR68662.1 - 6.5e-06 25.7 2.2 6.7e-05 22.3 1.5 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EMR68662.1 - 1.8e-05 24.5 0.1 0.35 10.5 0.0 2.9 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) DUF3439 PF11921.3 EMR68662.1 - 0.026 14.2 0.4 0.068 12.9 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DHQ_synthase PF01761.15 EMR68663.1 - 5.1e-73 245.1 0.0 1.5e-63 214.2 0.0 2.4 2 0 0 2 2 2 2 3-dehydroquinate synthase ADH_N PF08240.7 EMR68663.1 - 1e-10 41.3 0.0 3e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fe-ADH_2 PF13685.1 EMR68663.1 - 4.8e-10 39.1 0.3 0.00017 20.9 0.0 2.9 3 0 0 3 3 3 2 Iron-containing alcohol dehydrogenase Epimerase PF01370.16 EMR68663.1 - 5.5e-10 39.0 0.0 1.3e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fe-ADH PF00465.14 EMR68663.1 - 2e-06 26.6 0.2 0.015 13.9 0.1 3.8 4 0 0 4 4 4 2 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.15 EMR68663.1 - 1.5e-05 25.0 0.1 0.00051 20.1 0.1 2.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EMR68663.1 - 5.5e-05 22.6 0.1 0.46 9.9 0.0 3.3 3 0 0 3 3 3 2 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 EMR68663.1 - 0.00045 20.1 0.1 0.12 12.2 0.0 2.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMR68663.1 - 0.00091 19.2 0.8 0.0055 16.7 0.0 2.5 2 1 1 3 3 3 1 NADH(P)-binding ADH_zinc_N PF00107.21 EMR68663.1 - 0.003 17.1 1.2 0.0077 15.7 0.8 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.12 EMR68663.1 - 0.0053 15.6 0.0 0.085 11.7 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain ThiF PF00899.16 EMR68663.1 - 0.11 12.3 0.7 15 5.3 0.1 3.2 3 0 0 3 3 3 0 ThiF family NAD_binding_7 PF13241.1 EMR68663.1 - 0.15 12.2 0.3 0.44 10.8 0.2 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding NmrA PF05368.8 EMR68663.1 - 0.16 11.1 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family SspP PF08179.7 EMR68663.1 - 2.6 8.3 3.6 1.9 8.7 1.2 1.7 2 0 0 2 2 1 0 Small acid-soluble spore protein P family NPV_P10 PF05531.7 EMR68665.1 - 0.1 12.8 2.1 11 6.3 0.1 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Fructosamin_kin PF03881.9 EMR68666.1 - 5.5e-64 215.9 0.0 6.8e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EMR68666.1 - 0.03 14.0 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATP-grasp_2 PF08442.5 EMR68667.1 - 8.3e-66 221.2 1.4 9.2e-66 221.0 0.2 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 EMR68667.1 - 9.2e-27 93.5 0.5 1.8e-26 92.5 0.4 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EMR68667.1 - 6.2e-05 22.3 0.1 0.00014 21.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EMR68667.1 - 0.00087 18.8 1.1 0.034 13.7 0.1 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.1 EMR68667.1 - 0.014 15.0 0.2 1.2 8.7 0.0 2.4 1 1 1 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_4 PF13535.1 EMR68667.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Ribosomal_S11 PF00411.14 EMR68667.1 - 0.15 12.2 1.5 3.2 7.9 0.0 2.8 3 0 0 3 3 3 0 Ribosomal protein S11 Glyco_hydro_15 PF00723.16 EMR68668.1 - 2.6e-98 329.5 0.3 3.1e-98 329.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EMR68668.1 - 5.1e-34 115.7 2.6 1.4e-33 114.3 1.8 1.8 1 0 0 1 1 1 1 Starch binding domain KR PF08659.5 EMR68669.1 - 5e-40 137.1 6.0 1.4e-21 76.9 0.6 3.0 2 1 1 3 3 3 2 KR domain adh_short PF00106.20 EMR68669.1 - 4.4e-26 91.7 5.7 6.5e-13 48.9 1.0 3.4 2 1 1 3 3 3 2 short chain dehydrogenase ADH_zinc_N PF00107.21 EMR68669.1 - 2.9e-17 62.4 0.0 7.1e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR68669.1 - 2.4e-14 54.2 0.0 1.2e-13 52.1 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR68669.1 - 1.9e-09 37.2 0.1 4.8e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EMR68669.1 - 4.9e-08 33.1 0.0 1.3e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site SART-1 PF03343.8 EMR68670.1 - 4.5e-148 494.3 60.4 5.2e-148 494.1 41.9 1.0 1 0 0 1 1 1 1 SART-1 family Abhydrolase_6 PF12697.2 EMR68671.1 - 2.1e-18 67.0 0.1 3.5e-18 66.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR68671.1 - 5e-06 26.3 0.0 6.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EMR68671.1 - 0.0042 16.5 0.0 0.0077 15.6 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) AAA_17 PF13207.1 EMR68672.1 - 1e-06 29.5 0.0 2.8e-06 28.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain CPT PF07931.7 EMR68672.1 - 0.0003 20.4 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein PRK PF00485.13 EMR68672.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 EMR68672.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMR68672.1 - 0.023 15.0 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain CoaE PF01121.15 EMR68672.1 - 0.091 12.1 0.0 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase Zeta_toxin PF06414.7 EMR68672.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin ADH_N PF08240.7 EMR68673.1 - 2.4e-24 85.1 2.1 3.8e-24 84.5 1.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR68673.1 - 8e-20 70.7 0.0 1.2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR68673.1 - 7.3e-05 23.6 0.0 0.00013 22.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMR68673.1 - 0.0032 16.6 0.1 0.0052 15.9 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3391 PF11871.3 EMR68674.1 - 0.051 13.7 1.1 0.051 13.7 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) HJURP_C PF12347.3 EMR68674.1 - 0.058 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat WXG100 PF06013.7 EMR68674.1 - 0.091 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Plus-3 PF03126.13 EMR68676.1 - 1.7e-32 111.6 0.0 4.5e-32 110.3 0.0 1.7 1 0 0 1 1 1 1 Plus-3 domain PLDc PF00614.17 EMR68677.1 - 1.8e-17 62.5 0.7 2e-07 30.6 0.1 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EMR68677.1 - 2.5e-12 46.6 0.0 2.1e-07 30.7 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain IncA PF04156.9 EMR68678.1 - 0.014 15.0 32.7 0.17 11.4 10.5 2.3 1 1 1 2 2 2 0 IncA protein Fib_alpha PF08702.5 EMR68678.1 - 0.047 13.8 16.8 0.87 9.6 2.3 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.6 EMR68678.1 - 0.24 10.8 12.8 2.9 7.3 2.4 3.3 2 1 1 3 3 3 0 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.4 EMR68678.1 - 0.33 10.7 36.3 1.2 8.9 10.0 2.7 2 1 0 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YlqD PF11068.3 EMR68678.1 - 0.44 10.5 20.3 0.29 11.1 2.4 2.5 1 1 1 2 2 2 0 YlqD protein DUF3584 PF12128.3 EMR68678.1 - 0.45 7.7 23.7 0.61 7.3 16.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlxA PF14282.1 EMR68678.1 - 0.47 10.4 18.8 2.4 8.1 9.7 3.5 2 1 1 3 3 3 0 FlxA-like protein GldM_N PF12081.3 EMR68678.1 - 0.72 9.3 6.3 0.8 9.2 0.5 2.4 2 0 0 2 2 2 0 GldM N-terminal domain Tropomyosin PF00261.15 EMR68678.1 - 1.6 7.7 32.0 0.94 8.5 4.4 3.6 1 1 3 4 4 4 0 Tropomyosin IKKbetaNEMObind PF12179.3 EMR68678.1 - 1.9 8.3 6.0 0.27 11.0 0.1 2.5 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain CHD5 PF04420.9 EMR68678.1 - 2 8.0 7.0 2.2 7.9 3.5 2.1 1 1 0 1 1 1 0 CHD5-like protein GAS PF13851.1 EMR68678.1 - 2.2 7.4 25.8 0.53 9.4 7.5 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 EMR68678.1 - 3 7.6 37.4 0.02 14.7 17.6 2.5 2 1 1 3 3 2 0 Tropomyosin like DUF1664 PF07889.7 EMR68678.1 - 3.2 7.5 11.8 0.54 10.0 1.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) TMPIT PF07851.8 EMR68678.1 - 4.4 6.2 11.5 2.7 6.9 0.9 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF2450 PF10475.4 EMR68678.1 - 5.2 5.8 11.1 0.28 10.0 3.3 1.8 1 1 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) PA26 PF04636.8 EMR68678.1 - 8.1 5.0 10.3 2.1 6.9 4.8 1.7 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) adh_short PF00106.20 EMR68679.1 - 2e-16 60.3 0.8 1.2e-15 57.8 0.3 2.3 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR68679.1 - 5.2e-11 42.5 0.1 9.6e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EMR68679.1 - 0.0096 16.0 0.1 0.026 14.6 0.1 1.6 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EMR68679.1 - 0.047 12.6 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Epimerase PF01370.16 EMR68679.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMR68679.1 - 0.13 12.0 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pyr_redox_2 PF07992.9 EMR68680.1 - 9.9e-29 100.6 0.0 1.8e-28 99.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR68680.1 - 3.4e-13 49.7 4.3 7.7e-12 45.4 0.7 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR68680.1 - 3.2e-06 27.3 0.0 0.0074 16.3 0.0 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR68680.1 - 7.4e-05 21.8 0.0 0.3 9.9 0.0 2.9 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Reductase_C PF14759.1 EMR68680.1 - 0.00011 22.3 0.0 0.00025 21.2 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal Rieske PF00355.21 EMR68680.1 - 0.004 16.6 0.0 0.029 13.9 0.0 2.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_9 PF13454.1 EMR68680.1 - 0.0056 16.4 6.0 0.3 10.8 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EMR68680.1 - 0.014 15.6 0.8 0.25 11.6 0.0 2.4 1 1 1 2 2 2 0 Putative NAD(P)-binding Acetyltransf_10 PF13673.1 EMR68681.1 - 1e-10 41.7 0.9 1.4e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR68681.1 - 2.3e-06 27.5 0.0 5.9e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR68681.1 - 9.8e-05 22.4 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR68681.1 - 0.0035 17.1 0.0 0.012 15.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR68681.1 - 0.084 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Nitro_FeMo-Co PF02579.12 EMR68681.1 - 0.12 12.4 0.1 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Fungal_trans PF04082.13 EMR68682.1 - 1e-08 34.4 0.7 2.5e-08 33.1 0.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain NADH_u_ox_C PF12853.2 EMR68682.1 - 0.16 11.6 0.4 0.41 10.3 0.1 1.7 2 0 0 2 2 2 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit BTB PF00651.26 EMR68683.1 - 1.5e-15 57.1 0.0 2.5e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro_20 PF00728.17 EMR68685.1 - 2.5e-34 119.0 4.4 1.3e-33 116.6 3.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 EMR68685.1 - 6.5e-10 39.6 0.1 2.7e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 PAS_3 PF08447.6 EMR68685.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold Glyco_hydro_88 PF07470.8 EMR68686.1 - 6.6e-80 268.6 3.7 8e-80 268.3 2.6 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 EMR68686.1 - 0.0021 16.4 0.2 0.0027 16.0 0.1 1.1 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_76 PF03663.9 EMR68686.1 - 0.16 11.3 8.4 0.15 11.4 0.9 2.6 2 1 1 3 3 3 0 Glycosyl hydrolase family 76 OPT PF03169.10 EMR68687.1 - 2.8e-125 419.1 45.8 3.4e-51 174.4 11.8 3.4 2 1 1 3 3 3 3 OPT oligopeptide transporter protein SAPS PF04499.10 EMR68688.1 - 7.6e-195 648.0 0.0 1.4e-193 643.8 0.0 3.0 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein DUF4512 PF14975.1 EMR68688.1 - 0.61 10.9 3.2 23 5.8 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4512) CLASP_N PF12348.3 EMR68690.1 - 0.00056 19.3 0.0 0.014 14.7 0.0 2.4 2 0 0 2 2 2 1 CLASP N terminal Adaptin_N PF01602.15 EMR68690.1 - 0.0021 16.4 0.0 0.95 7.7 0.0 2.5 2 0 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.17 EMR68690.1 - 0.0031 17.4 2.1 1.6 9.0 0.0 5.3 6 0 0 6 6 6 1 HEAT repeat APG6 PF04111.7 EMR68690.1 - 0.029 13.4 7.1 0.054 12.5 4.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 MMS19_N PF14500.1 EMR68690.1 - 0.097 11.9 0.0 1.1 8.4 0.0 2.4 1 1 1 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II TPR_MLP1_2 PF07926.7 EMR68690.1 - 0.39 10.4 8.1 0.03 14.0 0.9 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 EMR68690.1 - 1.6 9.1 6.2 11 6.3 4.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Spore_III_AB PF09548.5 EMR68690.1 - 4.1 7.1 6.5 5.4 6.7 0.0 3.2 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) HALZ PF02183.13 EMR68690.1 - 4.4 7.0 9.1 3.7 7.3 1.9 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Nic96 PF04097.9 EMR68691.1 - 2.4e-204 680.0 0.0 2.9e-204 679.6 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 DUF3425 PF11905.3 EMR68692.1 - 3.8e-31 107.7 2.4 6.7e-31 106.9 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EMR68692.1 - 0.0029 17.5 7.0 0.0029 17.5 4.9 2.0 1 1 1 2 2 2 1 bZIP transcription factor DUF4164 PF13747.1 EMR68692.1 - 0.22 11.6 6.4 0.39 10.8 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) MerR-DNA-bind PF09278.6 EMR68692.1 - 1.9 8.9 6.8 1.1 9.7 2.8 2.0 1 1 1 2 2 2 0 MerR, DNA binding Glu_synthase PF01645.12 EMR68693.1 - 2.4e-155 516.9 0.0 3.6e-155 516.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EMR68693.1 - 7.9e-141 468.9 0.0 1.1e-140 468.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EMR68693.1 - 3.9e-114 380.7 0.0 8.5e-114 379.6 0.0 1.5 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EMR68693.1 - 5.9e-68 227.8 2.3 1.1e-67 226.9 1.6 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EMR68693.1 - 5.9e-23 80.6 0.1 1.2e-22 79.6 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EMR68693.1 - 8.4e-16 58.4 0.0 3.6e-15 56.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR68693.1 - 1.6e-10 41.3 0.2 0.00069 19.7 0.0 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR68693.1 - 3e-09 36.7 0.0 1.1e-08 34.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMR68693.1 - 3.7e-07 30.4 0.0 6.1e-05 23.3 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMR68693.1 - 1.4e-06 27.6 0.0 2.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EMR68693.1 - 3.3e-06 26.2 0.1 2.6e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR68693.1 - 2.8e-05 22.7 1.3 3.1e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EMR68693.1 - 0.00095 18.3 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR68693.1 - 0.0011 17.9 0.1 0.0035 16.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.14 EMR68693.1 - 0.0022 16.2 0.2 0.75 7.9 0.0 3.0 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like Thi4 PF01946.12 EMR68693.1 - 0.0038 16.3 2.0 0.0053 15.8 0.0 2.2 3 0 0 3 3 2 1 Thi4 family NAD_binding_7 PF13241.1 EMR68693.1 - 0.0064 16.7 2.2 1.7 8.9 0.1 3.1 3 0 0 3 3 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EMR68693.1 - 0.0085 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain AdoHcyase_NAD PF00670.16 EMR68693.1 - 0.011 15.5 0.8 5.1 6.9 0.0 2.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMR68693.1 - 0.022 14.5 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMN_dh PF01070.13 EMR68693.1 - 0.059 12.1 0.6 0.38 9.5 0.4 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase GIDA PF01134.17 EMR68693.1 - 0.13 11.0 0.8 0.66 8.7 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EMR68693.1 - 0.13 11.9 0.0 0.46 10.2 0.0 2.0 1 0 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EMR68693.1 - 0.37 10.4 1.0 0.46 10.1 0.0 1.7 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.1 EMR68693.1 - 0.42 9.4 0.0 15 4.3 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Glyco_hydro_47 PF01532.15 EMR68694.1 - 1.4e-164 548.0 0.0 1.7e-164 547.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 tRNA-synt_2b PF00587.20 EMR68694.1 - 0.041 13.4 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) WD40 PF00400.27 EMR68695.1 - 7.8e-48 158.7 10.6 1.1e-12 47.2 0.2 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EMR68695.1 - 6.9e-09 34.3 0.8 0.01 14.0 0.1 3.3 2 2 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EMR68695.1 - 0.097 10.9 0.0 2 6.5 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain VTC PF09359.5 EMR68696.1 - 1.8e-91 306.0 0.4 3.2e-91 305.2 0.2 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EMR68696.1 - 6.1e-19 68.8 16.0 1.5e-18 67.5 7.4 3.4 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 EMR68696.1 - 7.1e-09 35.7 1.4 7.1e-09 35.7 1.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Disaggr_repeat PF06848.6 EMR68696.1 - 0.02 14.3 0.1 0.048 13.0 0.0 1.6 1 0 0 1 1 1 0 Disaggregatase related repeat ADH_zinc_N PF00107.21 EMR68697.1 - 8.3e-20 70.6 0.0 1.5e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR68697.1 - 3.8e-05 24.5 0.0 7.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PGM_PMM_II PF02879.11 EMR68697.1 - 0.054 13.8 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II MFS_1 PF07690.11 EMR68698.1 - 3.8e-31 108.0 26.4 5e-31 107.6 18.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Transposase_28 PF04195.7 EMR68698.1 - 0.036 13.3 1.7 2.2 7.5 0.5 2.4 2 0 0 2 2 2 0 Putative gypsy type transposon ESSS PF10183.4 EMR68698.1 - 0.25 11.7 0.1 0.25 11.7 0.0 2.2 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) AA_permease PF00324.16 EMR68699.1 - 1.6e-141 471.9 39.9 1.8e-141 471.7 27.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR68699.1 - 6.9e-37 126.9 44.5 9.6e-37 126.5 30.8 1.1 1 0 0 1 1 1 1 Amino acid permease CHAT PF12770.2 EMR68700.1 - 1.6e-31 109.5 0.0 2.2e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 CHAT domain Peptidase_C25 PF01364.13 EMR68700.1 - 0.069 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 FGGY_C PF02782.11 EMR68702.1 - 3.5e-49 167.1 0.1 5e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EMR68702.1 - 5.7e-24 84.7 0.5 3.3e-22 79.0 0.3 2.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.16 EMR68702.1 - 0.025 13.9 0.0 0.074 12.3 0.0 1.7 2 0 0 2 2 2 0 Hexokinase Glycos_transf_2 PF00535.21 EMR68703.1 - 0.0015 18.2 0.0 0.0061 16.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_hydro_12 PF01670.11 EMR68704.1 - 5.7e-13 48.9 0.0 9.7e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 CENP-O PF09496.5 EMR68707.1 - 5.6e-21 74.5 0.0 1.2e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component CDC45 PF02724.9 EMR68707.1 - 0.15 10.0 2.2 0.22 9.5 1.6 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_jaz PF12171.3 EMR68708.1 - 1.1e-06 28.6 2.6 1.8e-06 27.8 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMR68708.1 - 0.00042 20.4 0.5 0.00069 19.7 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EMR68708.1 - 0.013 15.8 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EMR68708.1 - 0.031 14.6 0.8 0.054 13.8 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EMR68708.1 - 0.049 13.7 0.3 0.078 13.0 0.2 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 EMR68708.1 - 0.15 11.7 0.5 0.27 10.9 0.3 1.4 1 0 0 1 1 1 0 DBF zinc finger A_deaminase PF00962.17 EMR68709.1 - 1.2e-41 142.7 0.0 1.6e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase OTT_1508_deam PF14441.1 EMR68710.1 - 6e-09 35.8 1.0 1.6e-08 34.4 0.7 1.9 1 1 0 1 1 1 1 OTT_1508-like deaminase DUF3384 PF11864.3 EMR68710.1 - 0.015 13.8 0.1 0.024 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) DUF605 PF04652.11 EMR68710.1 - 6.4 6.0 18.9 0.42 9.9 9.4 1.7 2 0 0 2 2 2 0 Vta1 like Acatn PF13000.2 EMR68712.1 - 6.8e-154 513.3 24.1 7.6e-77 259.0 6.2 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF1691 PF07950.6 EMR68713.1 - 2.6e-37 127.1 7.1 3.4e-23 81.6 1.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1691) DUF4405 PF14358.1 EMR68713.1 - 0.006 16.6 0.1 3.6 7.7 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4405) Herpes_US9 PF06072.6 EMR68713.1 - 0.021 14.6 0.1 0.057 13.2 0.1 1.7 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 SCPU PF05229.10 EMR68714.1 - 0.029 14.4 0.1 0.037 14.1 0.1 1.2 1 0 0 1 1 1 0 Spore Coat Protein U domain TcpF PF06340.6 EMR68714.1 - 0.1 11.7 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Vibrio cholerae toxin co-regulated pilus biosynthesis protein F DUF4066 PF13278.1 EMR68715.1 - 3.2e-26 91.5 1.2 8e-26 90.2 0.9 1.6 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EMR68715.1 - 4.4e-11 42.4 0.0 5.7e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family EF-hand_2 PF09068.6 EMR68715.1 - 0.16 12.0 0.0 0.17 11.9 0.0 1.3 1 1 0 1 1 1 0 EF hand Sugar_tr PF00083.19 EMR68716.1 - 2.2e-59 201.2 15.7 1.3e-56 192.1 8.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR68716.1 - 2.9e-18 65.7 19.3 4.1e-18 65.2 13.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.17 EMR68717.1 - 6.5e-60 202.9 0.0 6.8e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EMR68718.1 - 0.0069 16.0 1.4 0.0069 16.0 0.1 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMR68718.1 - 0.12 12.0 0.1 0.32 10.7 0.1 1.7 1 0 0 1 1 1 0 F-box domain TPP_enzyme_N PF02776.13 EMR68719.1 - 8.6e-57 191.3 0.0 3.2e-56 189.5 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EMR68719.1 - 4.2e-49 166.0 0.0 1.8e-48 163.9 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMR68719.1 - 1.9e-36 124.8 0.3 4e-36 123.8 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain SDH_alpha PF03313.10 EMR68720.1 - 1.9e-80 269.9 14.0 3.1e-74 249.5 8.6 3.0 2 1 1 3 3 3 3 Serine dehydratase alpha chain SDH_beta PF03315.10 EMR68720.1 - 8.3e-51 172.1 0.0 1.5e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Serine dehydratase beta chain Fungal_trans_2 PF11951.3 EMR68721.1 - 0.032 12.8 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 EMR68723.1 - 8e-29 100.4 1.2 1.3e-28 99.6 0.8 1.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_1 PF00561.15 EMR68724.1 - 1.6e-13 50.7 0.0 3.6e-13 49.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR68724.1 - 7.4e-08 32.5 1.3 1.2e-07 31.9 0.3 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR68724.1 - 0.033 13.9 0.0 1.3 8.7 0.0 2.5 1 1 1 2 2 2 0 Alpha/beta hydrolase family Aldo_ket_red PF00248.16 EMR68725.1 - 1.9e-41 141.7 0.0 2.2e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UNC-93 PF05978.11 EMR68726.1 - 7.4e-12 45.0 8.3 7.4e-12 45.0 5.8 2.6 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EMR68726.1 - 2.1e-07 30.0 32.0 2.1e-07 30.0 22.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 EMR68727.1 - 6.4e-32 110.6 0.1 7.3e-32 110.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EMR68728.1 - 3.1e-31 108.3 26.1 4.3e-31 107.9 18.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SieB PF14163.1 EMR68728.1 - 0.053 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Superinfection exclusion protein B EutQ PF06249.7 EMR68729.1 - 6.5e-10 38.7 0.0 7.9e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 EMR68729.1 - 2.2e-08 33.3 0.0 2.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 EMR68729.1 - 4.7e-05 22.7 0.1 6.2e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EMR68729.1 - 0.014 15.0 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Cupin PhyH PF05721.8 EMR68730.1 - 7.6e-13 48.9 0.0 1.4e-12 48.1 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) FAD_binding_3 PF01494.14 EMR68732.1 - 7.3e-69 232.5 0.0 1.1e-68 231.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EMR68732.1 - 2.3e-56 190.0 0.0 4.7e-56 189.0 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Glyco_transf_28 PF03033.15 EMR68733.1 - 3.2e-23 82.0 0.0 8.8e-23 80.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Peptidase_M24 PF00557.19 EMR68734.1 - 4.9e-12 45.8 0.0 8.4e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Sugar_tr PF00083.19 EMR68735.1 - 2.4e-99 332.9 24.9 2.9e-99 332.7 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR68735.1 - 2.1e-23 82.6 33.0 1.4e-21 76.6 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MutL_C PF08676.6 EMR68735.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 MutL C terminal dimerisation domain Phage_holin_2 PF04550.7 EMR68735.1 - 0.12 12.4 1.7 0.49 10.5 1.2 2.1 1 0 0 1 1 1 0 Phage holin family 2 CAP PF00188.21 EMR68736.1 - 0.0012 19.3 0.0 0.0022 18.4 0.0 1.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family GST_N PF02798.15 EMR68737.1 - 1.3e-14 54.0 0.1 4.2e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMR68737.1 - 1.5e-13 50.7 0.0 2.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMR68737.1 - 8.6e-13 48.0 0.0 1.8e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR68737.1 - 3.3e-12 46.2 0.0 5.6e-12 45.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMR68737.1 - 1.8e-11 43.7 0.1 3.2e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR68737.1 - 2.4e-06 27.9 0.1 4.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 EMR68738.1 - 3.7e-15 55.5 48.5 9.5e-11 40.9 16.4 2.9 2 2 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 EMR68738.1 - 5.8e-08 31.3 20.0 7.5e-08 31.0 13.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GMC_oxred_N PF00732.14 EMR68739.1 - 3.1e-38 131.5 1.0 9.8e-30 103.7 0.1 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR68739.1 - 1.4e-34 119.4 0.0 3.3e-34 118.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMR68739.1 - 2.3e-07 30.0 2.6 0.002 17.0 0.3 2.2 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EMR68739.1 - 7.8e-07 29.1 0.1 1.3e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR68739.1 - 2.6e-06 26.5 0.8 0.00017 20.6 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR68739.1 - 3e-06 27.1 0.2 9e-06 25.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR68739.1 - 2.1e-05 24.6 1.4 0.00019 21.5 0.9 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR68739.1 - 0.00025 20.1 0.4 0.00055 18.9 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 EMR68739.1 - 0.0007 18.1 0.4 0.0096 14.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EMR68739.1 - 0.0017 18.7 0.1 0.011 16.1 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR68739.1 - 0.0048 15.8 0.1 0.22 10.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EMR68739.1 - 0.013 14.5 0.1 0.031 13.3 0.1 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EMR68739.1 - 0.014 15.1 0.7 0.042 13.6 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 EMR68739.1 - 0.029 14.3 0.3 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.14 EMR68739.1 - 0.058 12.4 0.1 0.14 11.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 EMR68740.1 - 8.6e-29 100.5 0.3 1.1e-28 100.1 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR68740.1 - 0.00033 20.9 1.9 0.0023 18.2 1.6 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR68740.1 - 0.029 14.4 0.1 0.087 12.8 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR68740.1 - 0.034 14.0 0.1 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR68740.1 - 0.063 12.1 0.1 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMR68740.1 - 0.09 12.8 0.2 0.29 11.1 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 EMR68740.1 - 0.1 12.2 0.1 3.6 7.2 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 EMR68740.1 - 0.35 9.9 1.7 0.45 9.5 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Sugar_tr PF00083.19 EMR68743.1 - 2.2e-18 66.0 4.1 2.4e-18 65.9 2.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Rab5ip PF07019.7 EMR68743.1 - 0.84 9.8 7.5 5.6 7.1 5.2 2.4 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) BTP PF05232.7 EMR68743.1 - 1.7 8.4 4.4 16 5.2 0.3 2.3 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family Aminotran_4 PF01063.14 EMR68744.1 - 2.8e-37 128.4 0.0 3.6e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV DUF2254 PF10011.4 EMR68744.1 - 0.2 10.1 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Rick_17kDa_Anti PF05433.10 EMR68745.1 - 0.00031 20.3 15.2 0.00031 20.3 10.6 1.8 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EMR68745.1 - 0.0093 15.6 0.8 0.022 14.4 0.5 1.7 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Nucleo_P87 PF07267.6 EMR68745.1 - 0.031 12.9 2.0 0.04 12.6 1.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PAT1 PF09770.4 EMR68745.1 - 0.17 10.1 12.1 0.21 9.7 8.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA PF00004.24 EMR68746.1 - 1.6e-17 63.9 0.0 4.8e-17 62.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMR68746.1 - 0.0015 18.5 0.0 0.0042 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMR68746.1 - 0.003 17.6 0.1 0.21 11.7 0.1 3.0 2 1 0 2 2 2 1 AAA domain SR-25 PF10500.4 EMR68746.1 - 0.16 11.3 13.3 0.27 10.6 9.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_11 PF13086.1 EMR68746.1 - 0.73 9.3 7.0 9.2 5.7 4.8 2.2 1 1 0 1 1 1 0 AAA domain CDC45 PF02724.9 EMR68746.1 - 0.76 7.7 9.2 1.1 7.2 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 EMR68746.1 - 0.8 9.5 11.4 1.3 8.9 7.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tcf25 PF04910.9 EMR68746.1 - 0.87 8.4 4.6 0.26 10.2 0.1 2.0 2 0 0 2 2 2 0 Transcriptional repressor TCF25 RNA_polI_A34 PF08208.6 EMR68746.1 - 3.4 7.2 18.8 5.7 6.5 13.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2796 PF10986.3 EMR68747.1 - 0.01 15.8 0.1 0.012 15.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Cutinase PF01083.17 EMR68748.1 - 3.1e-32 111.7 0.8 3.8e-32 111.4 0.6 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 EMR68748.1 - 0.073 12.8 0.1 0.081 12.6 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family NAD_binding_4 PF07993.7 EMR68749.1 - 1.1e-34 119.4 0.0 1.6e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EMR68749.1 - 1e-16 61.1 0.0 1.6e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMR68749.1 - 6.1e-08 32.8 0.0 1.6e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EMR68749.1 - 8.5e-07 29.0 0.7 3.4e-05 23.8 0.0 3.3 3 1 0 3 3 3 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EMR68749.1 - 4e-05 22.4 0.0 7.2e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EMR68749.1 - 0.00015 20.7 0.0 0.0056 15.6 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.5 EMR68749.1 - 0.0018 17.9 0.9 0.016 14.9 0.1 2.7 2 1 0 2 2 2 1 KR domain Pyridoxal_deC PF00282.14 EMR68753.1 - 4.3e-12 45.1 0.0 6.1e-05 21.6 0.0 2.4 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Glyco_hydro_3 PF00933.16 EMR68754.1 - 9.4e-85 284.1 0.0 1.3e-84 283.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR68754.1 - 4.5e-59 199.7 0.8 8.1e-59 198.8 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR68754.1 - 1.9e-23 82.2 0.0 3.2e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar_tr PF00083.19 EMR68755.1 - 8.6e-119 397.0 26.6 9.7e-119 396.8 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR68755.1 - 9.8e-19 67.2 46.7 1.4e-14 53.5 12.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.21 EMR68757.1 - 7.6e-12 44.9 0.0 1.4e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR68757.1 - 0.02 14.6 0.6 0.13 12.0 0.2 2.2 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain Aldo_ket_red PF00248.16 EMR68758.1 - 3.6e-60 203.1 0.0 4.6e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Collagen PF01391.13 EMR68759.1 - 5.2e-09 35.5 10.7 8.8e-09 34.7 7.4 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Tho2 PF11262.3 EMR68761.1 - 4.3e-74 249.2 0.2 6.2e-74 248.7 0.1 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EMR68761.1 - 2.1e-24 85.0 0.1 9.7e-24 82.9 0.0 2.2 2 0 0 2 2 2 1 Transcription- and export-related complex subunit AUX_IAA PF02309.11 EMR68761.1 - 1.8 8.2 4.5 0.72 9.5 0.3 2.3 3 0 0 3 3 3 0 AUX/IAA family HET PF06985.6 EMR68762.1 - 8.6e-17 61.5 4.8 3.3e-15 56.4 3.3 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_1 PF00561.15 EMR68763.1 - 4.6e-22 78.7 0.0 6e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR68763.1 - 0.0001 22.2 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EMR68763.1 - 0.0027 17.5 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein DUF556 PF04476.8 EMR68763.1 - 0.07 12.3 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF556) ABC_tran PF00005.22 EMR68764.1 - 4.5e-50 169.5 0.0 1.1e-29 103.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMR68764.1 - 8e-30 104.1 6.1 1.6e-16 60.5 0.1 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EMR68764.1 - 3.5e-10 39.4 0.8 0.00023 20.4 0.0 4.0 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EMR68764.1 - 3.7e-07 29.3 0.0 0.022 13.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 EMR68764.1 - 8.9e-06 26.1 0.5 0.025 14.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMR68764.1 - 9.3e-06 25.1 1.4 0.011 15.1 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EMR68764.1 - 1.4e-05 25.1 0.7 0.0028 17.6 0.2 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EMR68764.1 - 3.2e-05 23.3 1.7 0.055 12.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EMR68764.1 - 4.3e-05 23.6 0.0 0.048 13.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMR68764.1 - 0.00026 20.1 0.3 0.21 10.6 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_21 PF13304.1 EMR68764.1 - 0.0019 18.2 1.0 1.7 8.4 0.0 2.6 2 1 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EMR68764.1 - 0.0033 16.9 0.7 3.2 7.0 0.0 2.9 2 1 0 2 2 2 1 AAA-like domain AAA_30 PF13604.1 EMR68764.1 - 0.0054 16.3 0.4 2 7.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMR68764.1 - 0.0083 15.3 0.5 3 6.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EMR68764.1 - 0.0092 15.9 0.0 0.76 9.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EMR68764.1 - 0.0099 16.3 0.2 1.6 9.2 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 EMR68764.1 - 0.01 15.3 0.7 3.5 7.0 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.10 EMR68764.1 - 0.021 14.6 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.24 EMR68764.1 - 0.033 14.3 0.0 2.2 8.5 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMR68764.1 - 0.082 13.7 0.2 1.8 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 EMR68764.1 - 0.12 11.7 1.5 9.6 5.5 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF87 PF01935.12 EMR68764.1 - 0.13 12.0 5.5 1.8 8.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF2075 PF09848.4 EMR68764.1 - 0.25 10.2 0.0 9.8 5.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 EMR68764.1 - 0.28 10.8 3.2 6.5 6.4 0.1 3.4 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EMR68764.1 - 0.29 11.3 0.1 25 5.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 EMR68764.1 - 0.29 10.7 5.2 1.1 8.8 0.1 2.9 4 0 0 4 4 2 0 NACHT domain AAA_18 PF13238.1 EMR68764.1 - 0.34 11.2 1.4 3.8 7.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EMR68764.1 - 0.96 8.2 1.0 14 4.4 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain IstB_IS21 PF01695.12 EMR68764.1 - 0.97 8.8 4.9 1 8.7 0.0 3.0 4 0 0 4 4 3 0 IstB-like ATP binding protein cobW PF02492.14 EMR68764.1 - 2 7.7 2.7 24 4.3 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain VSP PF03302.8 EMR68765.1 - 2.7e-05 23.0 0.2 3.4e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Rax2 PF12768.2 EMR68765.1 - 0.0014 17.8 0.0 0.0018 17.5 0.0 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Podoplanin PF05808.6 EMR68765.1 - 0.0044 16.6 1.2 0.0044 16.6 0.8 1.7 1 1 1 2 2 2 1 Podoplanin MSA-2c PF12238.3 EMR68765.1 - 0.37 10.4 4.9 0.57 9.8 3.4 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c E1-E2_ATPase PF00122.15 EMR68767.1 - 1.3e-63 214.0 4.0 2.2e-63 213.3 2.8 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMR68767.1 - 2.9e-31 108.4 3.5 2.9e-31 108.4 2.4 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMR68767.1 - 1.1e-26 94.6 0.2 1.9e-21 77.4 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMR68767.1 - 4.9e-22 77.7 0.0 9.4e-22 76.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMR68767.1 - 2.1e-17 62.3 0.0 6.1e-17 60.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMR68767.1 - 9.9e-13 48.6 0.0 2.3e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMR68767.1 - 2e-07 30.8 0.4 1.2e-05 24.9 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ufm1 PF03671.9 EMR68767.1 - 0.068 12.9 0.4 0.6 9.9 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin fold modifier 1 protein Pkinase PF00069.20 EMR68768.1 - 0.00015 20.9 0.0 0.00016 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain adh_short PF00106.20 EMR68769.1 - 0.0012 18.7 0.0 0.0034 17.3 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68769.1 - 0.0014 18.3 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Glyco_hydro_18 PF00704.23 EMR68770.1 - 3.1e-21 76.2 3.2 1.9e-20 73.6 0.4 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Cupin_2 PF07883.6 EMR68771.1 - 3.5e-07 29.6 0.1 5.8e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.13 EMR68771.1 - 0.018 14.6 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase MCR_alpha PF02249.12 EMR68772.1 - 0.048 13.6 0.1 0.094 12.7 0.0 1.4 1 1 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain SnoaL PF07366.7 EMR68772.1 - 0.049 13.2 0.2 6.1 6.4 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase FAD_binding_4 PF01565.18 EMR68773.1 - 5.5e-16 58.3 1.1 1e-15 57.4 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR68773.1 - 7.1e-10 38.6 1.2 1.3e-09 37.7 0.5 1.8 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 EMR68773.1 - 0.006 15.7 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding CP_ATPgrasp_2 PF14403.1 EMR68774.1 - 1.7e-06 27.0 0.0 3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 ATPgrasp_ST PF14397.1 EMR68774.1 - 0.045 12.8 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Cupin_2 PF07883.6 EMR68775.1 - 3.9e-20 71.1 0.7 3.3e-18 64.9 0.3 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EMR68775.1 - 0.00038 20.1 0.3 0.00084 19.0 0.2 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 EMR68775.1 - 0.00053 19.3 0.0 0.015 14.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 EMR68775.1 - 0.0094 15.3 0.0 0.4 10.1 0.0 2.3 2 0 0 2 2 2 1 Cupin TauD PF02668.11 EMR68777.1 - 1.8e-05 24.5 0.0 2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.19 EMR68778.1 - 1.6e-47 162.1 23.6 2.4e-47 161.5 16.4 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR68778.1 - 4.2e-22 78.3 27.7 4.2e-22 78.3 19.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Caps_synth PF05704.7 EMR68779.1 - 2.5e-09 36.7 0.1 3.3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EMR68779.1 - 3.9e-09 36.8 0.1 8.4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMR68779.1 - 0.16 10.3 0.0 0.27 9.6 0.0 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain FLO_LFY PF01698.11 EMR68781.1 - 0.037 12.8 0.3 0.054 12.3 0.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein SprT-like PF10263.4 EMR68781.1 - 0.049 13.2 0.2 0.086 12.5 0.2 1.3 1 0 0 1 1 1 0 SprT-like family Inhibitor_I71 PF12628.2 EMR68781.1 - 2.1 7.9 11.8 1 9.0 0.1 2.2 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor Secretin_N_2 PF07655.8 EMR68781.1 - 6.9 7.1 13.4 13 6.2 9.3 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain TTL PF03133.10 EMR68782.1 - 9.2e-35 119.9 0.0 6.6e-34 117.1 0.0 1.9 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 EMR68782.1 - 0.0029 16.4 0.0 0.005 15.6 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.8 EMR68782.1 - 0.044 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 EMR68782.1 - 0.11 12.1 0.1 36 4.0 0.0 3.1 3 0 0 3 3 3 0 ATP-grasp domain Glyco_hydro_2_C PF02836.12 EMR68783.1 - 2.9e-99 331.7 0.0 3.9e-99 331.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 EMR68783.1 - 2.1e-53 180.3 0.2 3.8e-53 179.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Bgal_small_N PF02929.12 EMR68783.1 - 1.2e-48 165.5 0.0 2e-33 115.5 0.1 2.7 3 0 0 3 3 3 2 Beta galactosidase small chain Glyco_hydro_2 PF00703.16 EMR68783.1 - 1e-13 51.6 0.0 2.5e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EMR68783.1 - 0.012 15.8 0.0 0.038 14.2 0.0 1.8 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain MFS_1 PF07690.11 EMR68784.1 - 3e-28 98.5 91.0 1e-23 83.6 37.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR68784.1 - 2.3e-06 26.2 15.2 2.3e-06 26.2 10.5 2.3 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 EMR68784.1 - 0.025 14.3 0.6 0.025 14.3 0.4 3.9 4 0 0 4 4 4 0 MFS_1 like family AIM24 PF01987.12 EMR68785.1 - 4.7e-36 124.2 0.0 6.3e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PIP5K PF01504.13 EMR68786.1 - 6.2e-30 104.1 0.0 7.8e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Kinesin PF00225.18 EMR68788.1 - 1.6e-80 270.3 0.1 1.6e-80 270.3 0.1 1.5 2 0 0 2 2 2 1 Kinesin motor domain HHH_3 PF12836.2 EMR68788.1 - 0.007 16.2 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Trigger_C PF05698.9 EMR68788.1 - 0.046 13.5 3.5 0.09 12.6 2.4 1.5 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus TFIIA PF03153.8 EMR68788.1 - 1.1 9.0 16.6 2.3 8.0 11.5 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PQ-loop PF04193.9 EMR68789.1 - 2.9e-40 135.6 8.6 6.2e-20 70.4 0.4 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EMR68789.1 - 0.79 9.6 4.4 0.63 9.9 0.2 2.3 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange BTB PF00651.26 EMR68790.1 - 4.3e-12 46.0 0.0 5e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain NUDIX PF00293.23 EMR68791.1 - 7.2e-18 64.5 0.0 1.2e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EMR68791.1 - 1.1e-12 48.1 0.1 2.6e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EMR68791.1 - 1.4e-05 24.4 1.6 2.8e-05 23.5 1.1 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain LEA_1 PF03760.10 EMR68792.1 - 0.038 14.1 0.1 0.038 14.1 0.1 2.6 3 1 0 3 3 3 0 Late embryogenesis abundant (LEA) group 1 dCMP_cyt_deam_1 PF00383.17 EMR68793.1 - 5.7e-10 38.7 1.8 9.3e-09 34.8 1.2 2.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EMR68793.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase Arm PF00514.18 EMR68797.1 - 6e-13 48.0 0.4 1.1e-05 25.0 0.0 4.6 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EMR68797.1 - 0.0057 16.6 5.4 4.2 7.7 0.0 4.7 6 0 0 6 6 6 2 HEAT repeat INTS2 PF14750.1 EMR68797.1 - 0.038 11.5 0.0 0.054 11.0 0.0 1.2 1 0 0 1 1 1 0 Integrator complex subunit 2 Ank_5 PF13857.1 EMR68798.1 - 5.2e-15 55.1 0.0 8.1e-12 44.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EMR68798.1 - 7.2e-15 53.9 0.0 1.8e-08 33.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EMR68798.1 - 1.6e-13 50.7 0.0 3.1e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMR68798.1 - 4.8e-12 46.0 0.1 6.3e-08 32.9 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) TIG PF01833.19 EMR68798.1 - 5.8e-12 45.4 0.7 2.5e-11 43.3 0.5 2.1 1 0 0 1 1 1 1 IPT/TIG domain Ank_3 PF13606.1 EMR68798.1 - 9.5e-12 43.9 0.0 1.2e-05 25.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Cauli_VI PF01693.11 EMR68799.1 - 5.3e-30 103.1 4.9 1.5e-15 56.9 0.3 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EMR68799.1 - 1e-27 97.0 0.2 2.1e-27 96.0 0.1 1.5 1 0 0 1 1 1 1 RNase H PBP1_TM PF14812.1 EMR68799.1 - 0.05 13.8 5.1 0.098 12.9 3.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2890 PF11081.3 EMR68799.1 - 0.16 11.9 5.6 0.26 11.3 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Myc_N PF01056.13 EMR68799.1 - 1 8.4 5.6 1.5 7.9 3.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF4611 PF15387.1 EMR68799.1 - 1.2 9.3 8.1 2.7 8.2 5.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 EMR68799.1 - 2.3 7.6 11.9 3.7 7.0 8.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin 6PF2K PF01591.13 EMR68800.1 - 3.4e-60 202.8 0.0 1.5e-44 151.7 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EMR68800.1 - 5.6e-24 85.0 0.1 3e-23 82.6 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EMR68800.1 - 0.015 15.1 0.0 0.056 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoU PF01895.14 EMR68800.1 - 0.1 13.0 0.1 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 PhoU domain Sigma70_r4_2 PF08281.7 EMR68800.1 - 0.12 11.8 0.1 2.4 7.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-70, region 4 FAD_binding_3 PF01494.14 EMR68801.1 - 2.3e-25 89.4 0.1 7e-25 87.8 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMR68801.1 - 0.00095 19.1 0.1 0.0021 18.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMR68801.1 - 0.014 14.2 1.3 0.053 12.3 0.3 2.0 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 EMR68801.1 - 0.024 13.5 3.0 0.28 10.0 0.2 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR68801.1 - 0.066 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1789 PF08748.6 EMR68801.1 - 0.1 12.7 0.0 0.24 11.4 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1789) Trp_halogenase PF04820.9 EMR68801.1 - 0.17 10.4 0.9 2 6.9 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_8 PF13450.1 EMR68802.1 - 2.5e-10 40.2 0.1 5.9e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMR68802.1 - 1.8e-06 27.3 0.0 3.1e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EMR68802.1 - 5.9e-05 23.2 0.4 0.00015 21.8 0.1 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMR68802.1 - 0.004 16.2 0.1 0.012 14.7 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EMR68802.1 - 0.004 17.0 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR68802.1 - 0.012 14.0 0.0 0.018 13.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.13 EMR68802.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 EMR68802.1 - 0.028 14.1 0.0 0.13 12.0 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.12 EMR68802.1 - 0.049 12.7 0.2 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.2 EMR68802.1 - 0.052 12.6 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR68802.1 - 0.057 12.2 0.1 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 EMR68802.1 - 0.096 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Cyclin PF08613.6 EMR68803.1 - 1.2e-21 77.6 0.1 1.7e-21 77.2 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EMR68803.1 - 0.002 17.6 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain CHZ PF09649.5 EMR68804.1 - 6.8e-18 63.6 1.3 6.8e-18 63.6 0.9 2.6 2 1 0 3 3 3 1 Histone chaperone domain CHZ MMtag PF10159.4 EMR68804.1 - 2.6 8.1 5.6 1.1 9.3 2.2 1.7 1 1 1 2 2 2 0 Kinase phosphorylation protein HATPase_c PF02518.21 EMR68807.1 - 2.8e-28 97.8 0.0 5.8e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMR68807.1 - 5.5e-21 74.6 0.2 1.3e-20 73.5 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EMR68807.1 - 1.4e-18 66.6 0.3 1.4e-18 66.6 0.2 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 EMR68807.1 - 1.6e-08 35.2 0.0 4.2e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EMR68807.1 - 9.1e-07 29.0 0.0 2.1e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.1 EMR68807.1 - 0.00068 19.3 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Prenylcys_lyase PF07156.9 EMR68808.1 - 5.5e-33 114.3 0.0 7.8e-24 84.2 0.0 2.1 2 0 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 EMR68808.1 - 1.9e-13 50.2 0.2 9.7e-13 47.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMR68808.1 - 8.4e-08 31.7 0.0 3.1e-06 26.5 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EMR68808.1 - 1.7e-05 24.6 0.1 7.5e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EMR68808.1 - 2.2e-05 23.5 0.1 6.7e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR68808.1 - 0.00016 21.6 0.6 0.019 14.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR68808.1 - 0.00093 18.3 0.1 0.05 12.6 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EMR68808.1 - 0.02 14.9 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EMR68808.1 - 0.033 14.2 0.1 0.075 13.1 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EMR68808.1 - 0.092 11.5 0.2 0.16 10.7 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EMR68808.1 - 0.1 11.1 0.5 0.19 10.2 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 EMR68808.1 - 0.73 8.6 3.3 0.22 10.3 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Cpn60_TCP1 PF00118.19 EMR68809.1 - 3e-146 487.8 0.2 3.4e-146 487.6 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family COesterase PF00135.23 EMR68811.1 - 1.8e-86 291.0 0.0 2.7e-86 290.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR68811.1 - 2.8e-08 33.5 0.3 3.8e-07 29.8 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DEC-1_N PF04625.8 EMR68811.1 - 0.13 10.9 1.6 0.25 9.9 1.1 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region eIF-3_zeta PF05091.7 EMR68812.1 - 1.9e-198 660.3 0.0 2.2e-198 660.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 EMR68812.1 - 0.083 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF569) PAS PF00989.19 EMR68813.1 - 1.3e-05 24.9 0.1 8.2e-05 22.3 0.0 2.0 1 1 1 2 2 2 1 PAS fold PAS_9 PF13426.1 EMR68813.1 - 0.0015 18.8 0.0 0.0029 17.9 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 EMR68813.1 - 0.077 13.0 0.0 0.37 10.8 0.0 1.9 1 1 1 2 2 2 0 PAS fold PAS_3 PF08447.6 EMR68813.1 - 0.089 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 PAS fold Serpentine_r_xa PF03383.10 EMR68814.1 - 0.086 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa Ribul_P_3_epim PF00834.14 EMR68815.1 - 2.3e-61 206.4 0.0 9.7e-61 204.3 0.0 1.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 EMR68815.1 - 0.036 13.4 0.4 0.11 11.9 0.2 1.8 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Nop14 PF04147.7 EMR68816.1 - 0.0013 16.7 23.0 0.0013 16.7 16.0 1.6 2 0 0 2 2 2 1 Nop14-like family CytochromB561_N PF09786.4 EMR68816.1 - 0.077 11.4 0.1 0.1 10.9 0.1 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal DNA_pol_phi PF04931.8 EMR68816.1 - 0.34 8.6 17.0 0.46 8.1 11.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.4 EMR68816.1 - 0.77 8.4 31.8 0.097 11.3 16.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EMR68816.1 - 2.4 6.0 19.5 0.026 12.6 8.2 1.6 2 0 0 2 2 2 0 CDC45-like protein DUF2890 PF11081.3 EMR68816.1 - 9.5 6.2 12.4 1.3 9.0 5.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Ofd1_CTDD PF10637.4 EMR68817.1 - 1.8e-97 325.6 0.0 8.2e-91 303.8 0.1 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EMR68817.1 - 2.3e-14 53.6 0.0 6e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Macoilin PF09726.4 EMR68817.1 - 0.11 10.8 7.3 0.17 10.1 2.0 2.1 2 0 0 2 2 2 0 Transmembrane protein DDHD PF02862.12 EMR68817.1 - 8.3 6.1 17.3 8.8 6.0 0.1 3.1 3 0 0 3 3 3 0 DDHD domain NAD_binding_4 PF07993.7 EMR68819.1 - 1.3e-41 142.1 0.1 6.1e-40 136.7 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein PP-binding PF00550.20 EMR68819.1 - 5.8e-10 39.2 0.0 1.2e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EMR68819.1 - 4.3e-09 36.1 0.0 6.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR68819.1 - 7.9e-05 21.4 0.0 0.00014 20.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMR68819.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 EMR68819.1 - 0.057 13.0 0.0 0.24 11.0 0.0 2.1 1 1 0 1 1 1 0 KR domain YbgS PF13985.1 EMR68820.1 - 0.09 12.6 0.3 0.094 12.6 0.2 1.2 1 0 0 1 1 1 0 YbgS-like protein TRAPP PF04051.11 EMR68821.1 - 2e-12 46.9 0.0 2.4e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PqqD PF05402.7 EMR68821.1 - 0.089 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) DUF4250 PF14056.1 EMR68821.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) PBP1_TM PF14812.1 EMR68822.1 - 0.0013 18.9 4.6 0.0027 17.9 1.4 2.5 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Arteri_Gl PF00951.13 EMR68822.1 - 0.064 12.8 0.1 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein WD40 PF00400.27 EMR68823.1 - 6.5e-42 139.9 6.1 2e-06 27.4 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMR68823.1 - 6e-05 21.9 1.2 0.096 11.4 0.1 2.3 1 1 1 2 2 2 2 Nup133 N terminal like Pkinase PF00069.20 EMR68824.1 - 2.5e-76 256.2 0.0 3.5e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR68824.1 - 8.4e-39 133.1 0.0 3.6e-38 131.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR68824.1 - 5.3e-11 42.0 0.0 1.8e-09 37.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FHA PF00498.21 EMR68824.1 - 3e-05 24.0 0.0 8.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 EMR68824.1 - 0.0045 16.0 0.0 0.009 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EMR68824.1 - 0.0052 15.6 0.1 0.01 14.6 0.1 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 EMR68824.1 - 0.098 12.3 0.1 0.82 9.3 0.1 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family ArfGap PF01412.13 EMR68825.1 - 2.4e-34 117.6 0.5 5.7e-34 116.3 0.0 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EMR68825.1 - 1.4e-06 28.4 0.1 1e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 PH domain Syntaxin_2 PF14523.1 EMR68825.1 - 0.031 14.2 2.0 1.5 8.9 0.1 2.9 2 0 0 2 2 2 0 Syntaxin-like protein Ank_2 PF12796.2 EMR68825.1 - 0.054 13.8 0.0 0.21 11.9 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Phasin_2 PF09361.5 EMR68825.1 - 0.12 12.4 2.1 0.38 10.7 0.0 2.4 2 1 0 2 2 2 0 Phasin protein EMP24_GP25L PF01105.19 EMR68825.1 - 0.3 10.7 2.6 3.5 7.2 1.6 2.5 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD HAMP PF00672.20 EMR68826.1 - 4.8e-47 158.0 17.2 4e-09 36.5 0.1 7.0 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 EMR68826.1 - 1.3e-28 98.9 0.2 4.3e-28 97.2 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMR68826.1 - 7.5e-28 96.7 0.2 2e-26 92.2 0.2 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EMR68826.1 - 2e-18 66.1 5.8 2.2e-18 66.0 0.4 3.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF883 PF05957.8 EMR68826.1 - 0.00033 20.9 9.1 0.51 10.7 0.0 5.2 4 1 1 5 5 5 2 Bacterial protein of unknown function (DUF883) AAA_13 PF13166.1 EMR68826.1 - 0.0037 15.7 14.2 0.096 11.1 1.0 3.7 1 1 2 4 4 4 3 AAA domain DUF2365 PF10157.4 EMR68826.1 - 0.18 11.6 13.9 16 5.3 0.1 6.5 5 1 2 7 7 7 0 Uncharacterized conserved protein (DUF2365) Rotamase PF00639.16 EMR68826.1 - 0.4 11.4 7.0 21 5.9 0.1 5.2 3 2 2 5 5 5 0 PPIC-type PPIASE domain NAAA-beta PF15508.1 EMR68826.1 - 0.92 9.9 4.0 27 5.1 0.1 5.0 4 3 3 7 7 7 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Pox_A_type_inc PF04508.7 EMR68826.1 - 1.7 8.5 11.1 0.42 10.5 0.1 5.0 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat DUF948 PF06103.6 EMR68826.1 - 2.6 7.9 30.0 7.6 6.4 0.2 8.2 4 1 2 8 8 8 0 Bacterial protein of unknown function (DUF948) NUDIX PF00293.23 EMR68827.1 - 8.3e-14 51.3 0.0 1.6e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Membr_traf_MHD PF10540.4 EMR68828.1 - 7.9e-24 84.0 0.3 2.5e-23 82.4 0.1 2.1 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EMR68828.1 - 4.3e-18 64.9 0.1 1.2e-17 63.5 0.1 1.8 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 EMR68828.1 - 0.00019 19.8 1.2 0.00072 17.9 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF810) Rep_N PF08724.5 EMR68828.1 - 0.027 14.0 0.0 0.076 12.5 0.0 1.7 1 0 0 1 1 1 0 Rep protein catalytic domain like PLDc PF00614.17 EMR68829.1 - 1.3e-15 56.6 1.7 2.3e-07 30.4 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EMR68829.1 - 5.4e-12 45.5 0.1 4.1e-06 26.5 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain DEAD PF00270.24 EMR68830.1 - 3.3e-41 140.6 0.7 4.8e-41 140.0 0.2 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR68830.1 - 1.2e-18 66.7 0.0 2.5e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EMR68830.1 - 9.4e-15 53.9 0.0 1.9e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EMR68830.1 - 0.0053 16.6 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UPF0086 PF01868.11 EMR68832.1 - 2.2e-24 84.9 0.3 3.6e-24 84.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 adh_short PF00106.20 EMR68833.1 - 5.2e-14 52.4 0.1 9.9e-14 51.5 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR68833.1 - 1.2e-07 31.6 0.0 1.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR68833.1 - 0.0041 16.5 0.0 0.013 14.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR68833.1 - 0.01 15.8 0.4 0.027 14.4 0.3 1.9 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 EMR68833.1 - 0.088 11.4 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMR68833.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TPR_11 PF13414.1 EMR68834.1 - 8.7e-12 44.5 6.0 1.3e-11 43.9 2.5 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EMR68834.1 - 3.7e-06 26.4 3.5 0.0087 15.8 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMR68834.1 - 3.5e-05 23.2 4.5 0.13 11.9 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMR68834.1 - 6.7e-05 22.7 2.5 0.0002 21.2 1.7 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EMR68834.1 - 0.00022 21.3 1.7 0.0004 20.4 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EMR68834.1 - 0.00029 20.4 1.2 0.82 9.6 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat DUF2413 PF10310.4 EMR68834.1 - 0.00045 19.1 10.4 0.00045 19.1 7.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2413) TPR_19 PF14559.1 EMR68834.1 - 0.0032 17.7 0.2 0.0099 16.1 0.1 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMR68834.1 - 0.012 16.1 0.6 0.61 10.8 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat HAD_2 PF13419.1 EMR68835.1 - 8.1e-23 81.5 0.0 1.1e-22 81.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR68835.1 - 5.3e-05 23.7 0.0 6.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EMR68835.1 - 0.006 16.4 0.1 0.04 13.8 0.0 2.4 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR68835.1 - 0.006 16.2 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Snf7 PF03357.16 EMR68836.1 - 9.6e-17 60.8 12.1 1.5e-16 60.2 8.4 1.3 1 0 0 1 1 1 1 Snf7 DUF348 PF03990.9 EMR68836.1 - 0.065 12.8 2.5 0.32 10.6 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF348) DUF4600 PF15372.1 EMR68836.1 - 0.4 10.9 5.0 3.5 7.8 0.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) CorA PF01544.13 EMR68836.1 - 0.71 8.8 5.0 0.23 10.4 0.5 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein IncA PF04156.9 EMR68836.1 - 2 7.9 9.2 1.1 8.7 1.9 2.2 2 0 0 2 2 2 0 IncA protein Spb1_C PF07780.7 EMR68836.1 - 6 6.2 10.4 0.28 10.6 2.7 1.9 2 0 0 2 2 2 0 Spb1 C-terminal domain Mnd1 PF03962.10 EMR68836.1 - 8 6.0 8.2 3.2 7.3 1.7 2.3 2 0 0 2 2 2 0 Mnd1 family TauD PF02668.11 EMR68837.1 - 4.6e-55 187.0 1.1 5.5e-55 186.8 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans_2 PF11951.3 EMR68838.1 - 7.8e-09 34.6 1.2 1.2e-08 34.0 0.8 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain PPR_2 PF13041.1 EMR68839.1 - 5e-56 186.4 7.8 2.2e-09 37.1 0.0 14.5 10 3 5 15 15 15 12 PPR repeat family PPR_3 PF13812.1 EMR68839.1 - 1.7e-31 105.8 24.0 6.8e-05 22.8 0.0 15.9 18 0 0 18 18 18 7 Pentatricopeptide repeat domain PPR PF01535.15 EMR68839.1 - 1.9e-30 102.6 22.4 7.7e-05 22.4 0.1 14.0 17 0 0 17 17 17 6 PPR repeat PPR_1 PF12854.2 EMR68839.1 - 3.6e-30 103.1 2.7 1.8e-08 33.7 0.0 12.3 14 0 0 14 14 14 6 PPR repeat RPM2 PF08579.6 EMR68839.1 - 2.6e-06 27.5 0.1 0.0082 16.2 0.0 4.9 6 1 0 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.2 EMR68839.1 - 0.0019 17.5 0.4 0.056 12.8 0.1 3.4 3 1 0 3 3 3 1 Mitochondrial ATPase expression TPR_8 PF13181.1 EMR68839.1 - 0.0083 15.8 3.9 7.3 6.6 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMR68839.1 - 0.12 12.0 1.7 8.1 6.2 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ECSIT PF06239.6 EMR68839.1 - 0.12 11.2 0.0 6.9 5.4 0.0 2.5 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_2 PF07719.12 EMR68839.1 - 0.4 10.6 2.5 21 5.3 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 EMR68840.1 - 5.6e-10 38.7 9.5 1e-09 37.8 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMR68840.1 - 1.1e-08 34.5 7.2 1.9e-08 33.8 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMR68840.1 - 2e-08 34.0 9.9 3.8e-08 33.2 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR68840.1 - 3.4e-08 33.0 9.2 7e-08 32.0 6.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EMR68840.1 - 6.1e-08 32.3 9.0 1.2e-07 31.3 6.2 1.6 1 0 0 1 1 1 1 Ring finger domain SAP PF02037.22 EMR68840.1 - 1.2e-07 31.0 0.1 2.3e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 SAP domain zf-RING_6 PF14835.1 EMR68840.1 - 1.5e-06 27.8 2.1 2.7e-06 27.0 1.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EMR68840.1 - 4.6e-06 26.4 9.2 1.2e-05 25.0 6.3 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EMR68840.1 - 5.5e-05 22.8 6.5 0.00012 21.6 4.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EMR68840.1 - 8.8e-05 22.5 3.2 0.00019 21.4 2.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger U-box PF04564.10 EMR68840.1 - 0.00027 20.8 0.5 0.022 14.7 0.0 2.3 2 0 0 2 2 2 1 U-box domain zf-RING_4 PF14570.1 EMR68840.1 - 0.00053 19.5 1.9 0.00053 19.5 1.3 2.5 3 0 0 3 3 2 1 RING/Ubox like zinc-binding domain Mob_synth_C PF06463.8 EMR68840.1 - 0.019 14.6 3.3 0.019 14.6 2.3 1.9 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C zf-Apc11 PF12861.2 EMR68840.1 - 0.032 14.0 0.8 0.032 14.0 0.5 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EMR68840.1 - 0.099 12.1 3.8 0.19 11.2 2.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 EMR68840.1 - 0.18 11.3 8.4 0.11 12.0 3.9 2.0 2 0 0 2 2 2 0 P-11 zinc finger BTB PF00651.26 EMR68841.1 - 0.0022 17.9 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF260 PF03195.9 EMR68841.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF260 Amidase PF01425.16 EMR68842.1 - 1.3e-91 307.7 0.0 3.9e-66 223.7 0.4 2.2 2 0 0 2 2 2 2 Amidase DIM PF08194.7 EMR68843.1 - 0.093 12.7 0.3 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 DIM protein NmrA PF05368.8 EMR68845.1 - 6.2e-41 140.1 0.0 8e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR68845.1 - 1.4e-25 90.3 0.1 1.8e-25 90.0 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR68845.1 - 2.5e-06 27.1 0.1 1.1e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR68845.1 - 0.00011 21.2 0.0 0.033 13.0 0.1 2.2 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.20 EMR68845.1 - 0.0014 18.5 0.3 0.0022 17.9 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 EMR68845.1 - 0.0077 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 EMR68845.1 - 0.016 15.6 0.3 0.053 13.9 0.2 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EMR68845.1 - 0.032 13.8 0.3 0.06 12.9 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cons_hypoth95 PF03602.10 EMR68845.1 - 0.093 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PAC2 PF09754.4 EMR68845.1 - 0.16 11.7 1.2 38 4.0 0.0 3.0 2 1 1 3 3 3 0 PAC2 family SNARE PF05739.14 EMR68846.1 - 0.00011 21.8 2.6 0.00015 21.3 1.8 1.3 1 1 0 1 1 1 1 SNARE domain DUF4446 PF14584.1 EMR68846.1 - 0.072 12.9 0.1 0.079 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) BRE1 PF08647.6 EMR68846.1 - 0.08 12.9 0.7 0.1 12.5 0.5 1.1 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Synaptobrevin PF00957.16 EMR68846.1 - 0.1 12.2 0.1 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Synaptobrevin RasGAP_C PF03836.10 EMR68846.1 - 0.14 11.8 1.1 0.17 11.6 0.8 1.1 1 0 0 1 1 1 0 RasGAP C-terminus MFS_1 PF07690.11 EMR68847.1 - 8.7e-51 172.6 25.2 8.7e-51 172.6 17.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_11 PF08241.7 EMR68848.1 - 9.5e-05 22.8 0.0 0.00014 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR68848.1 - 0.00041 19.9 0.0 0.00046 19.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CDC27 PF09507.5 EMR68849.1 - 1.7e-66 225.2 47.5 1e-47 163.3 28.5 2.0 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 Fe_dep_repress PF01325.14 EMR68849.1 - 0.0092 15.9 0.2 2.1 8.3 0.0 3.0 3 0 0 3 3 3 2 Iron dependent repressor, N-terminal DNA binding domain DUF1762 PF08574.5 EMR68850.1 - 0.015 15.7 5.1 0.032 14.6 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1762) Nucleoplasmin PF03066.10 EMR68850.1 - 0.023 14.1 4.2 0.036 13.5 2.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin Glyco_hydro_92 PF07971.7 EMR68851.1 - 8.5e-125 417.2 0.0 1.2e-101 340.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 NMD3 PF04981.8 EMR68852.1 - 8.2e-55 185.4 3.0 1.2e-54 184.9 2.1 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 EMR68852.1 - 3.4 7.5 9.8 25 4.7 5.0 2.7 2 1 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.17 EMR68852.1 - 7.7 6.3 9.1 0.33 10.6 1.3 2.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DPBB_1 PF03330.13 EMR68853.1 - 1.3e-07 31.4 2.5 2e-07 30.8 0.2 2.2 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EMR68853.1 - 0.0014 18.3 0.5 0.0019 17.8 0.3 1.3 1 1 0 1 1 1 1 Barwin family CDC48_N PF02359.13 EMR68853.1 - 0.03 14.2 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Acyltransferase PF01553.16 EMR68854.1 - 1.4e-05 24.5 0.0 2.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Terpene_synth PF01397.16 EMR68854.1 - 0.038 13.3 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain RAP PF08373.5 EMR68854.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 RAP domain Aminotran_1_2 PF00155.16 EMR68855.1 - 1.2e-85 287.6 0.0 1.3e-85 287.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sugar_tr PF00083.19 EMR68856.1 - 2.2e-72 244.0 26.1 6.2e-66 222.8 14.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR68856.1 - 4.2e-27 94.7 50.1 1.1e-26 93.3 34.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EMR68856.1 - 5.6e-05 21.3 5.7 0.01 13.9 0.0 3.2 2 2 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Folate_carrier PF01770.13 EMR68856.1 - 0.038 12.5 2.9 0.052 12.0 2.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier GLTP PF08718.6 EMR68857.1 - 1.3e-46 158.3 0.0 3.3e-46 157.0 0.0 1.6 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) adh_short PF00106.20 EMR68858.1 - 1.8e-14 53.9 0.0 2.5e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68858.1 - 3.5e-06 26.8 0.0 4.9e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 KR domain HAD_2 PF13419.1 EMR68859.1 - 1.2e-10 41.9 0.0 0.00011 22.4 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR68859.1 - 0.00011 21.8 0.0 0.00033 20.3 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EMR68859.1 - 0.0013 19.1 0.0 0.33 11.3 0.0 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase TRAPPC-Trs85 PF12739.2 EMR68860.1 - 6e-58 196.4 3.0 7.2e-58 196.2 2.1 1.0 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Isochorismatase PF00857.15 EMR68861.1 - 2.6e-18 66.5 0.0 2.1e-17 63.6 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family DUF1996 PF09362.5 EMR68862.1 - 2.2e-61 207.5 2.7 6.1e-34 117.7 0.6 2.1 1 1 0 2 2 2 2 Domain of unknown function (DUF1996) 2OG-FeII_Oxy PF03171.15 EMR68863.1 - 3.5e-14 52.8 0.0 7.5e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMR68863.1 - 6.4e-13 49.2 0.0 1.3e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal NSP10 PF09401.5 EMR68864.1 - 0.16 11.6 1.3 0.28 10.9 0.9 1.3 1 0 0 1 1 1 0 RNA synthesis protein NSP10 SnoaL PF07366.7 EMR68865.1 - 3.8e-29 100.8 0.4 3.3e-25 88.1 0.1 3.3 2 1 1 3 3 3 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EMR68865.1 - 4.7e-11 42.9 0.5 1e-09 38.7 0.0 2.7 2 1 1 3 3 3 1 SnoaL-like domain COesterase PF00135.23 EMR68866.1 - 9.3e-06 24.6 0.0 1e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Ank_2 PF12796.2 EMR68868.1 - 1.2e-44 150.5 12.3 6.6e-11 42.4 0.5 4.3 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMR68868.1 - 3.7e-21 75.0 0.1 5.3e-05 23.6 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EMR68868.1 - 1.7e-19 68.5 5.4 0.00025 20.7 0.0 6.6 7 2 0 7 7 6 4 Ankyrin repeat Ank_5 PF13857.1 EMR68868.1 - 2.4e-16 59.3 0.1 2.2e-05 24.5 0.0 4.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR68868.1 - 4e-14 51.3 0.2 0.0013 18.7 0.0 5.9 5 0 0 5 5 5 2 Ankyrin repeat TPR_12 PF13424.1 EMR68868.1 - 9.8e-06 25.4 0.6 0.0001 22.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EMR68868.1 - 0.0017 18.0 1.1 0.0097 15.7 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMR68868.1 - 0.0071 16.2 0.0 0.03 14.2 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF1664 PF07889.7 EMR68868.1 - 0.018 14.8 0.5 0.054 13.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_19 PF14559.1 EMR68868.1 - 0.045 14.0 0.5 0.47 10.8 0.2 2.8 1 1 0 1 1 1 0 Tetratricopeptide repeat WEMBL PF05701.6 EMR68868.1 - 0.047 12.1 1.9 0.057 11.8 0.6 1.6 2 0 0 2 2 2 0 Weak chloroplast movement under blue light TPR_1 PF00515.23 EMR68868.1 - 0.055 13.0 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1640 PF07798.6 EMR68868.1 - 0.056 13.4 5.5 0.61 10.1 3.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) TPR_11 PF13414.1 EMR68868.1 - 0.08 12.6 0.3 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.1 EMR68868.1 - 0.083 13.1 0.0 0.34 11.2 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMR68868.1 - 0.11 13.2 0.3 0.37 11.5 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF342 PF03961.8 EMR68868.1 - 0.19 10.0 1.7 0.21 9.9 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EMR68868.1 - 0.24 10.9 10.0 0.077 12.5 4.7 1.8 2 0 0 2 2 1 0 IncA protein Serglycin PF04360.7 EMR68868.1 - 0.25 11.0 4.8 1 9.0 3.3 1.9 2 0 0 2 2 2 0 Serglycin Spc24 PF08286.6 EMR68868.1 - 2.1 8.0 6.4 1.9 8.2 1.3 2.7 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 UPF0029 PF01205.14 EMR68869.1 - 3.1e-18 65.4 0.0 8.1e-18 64.1 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 DUF1002 PF06207.6 EMR68869.1 - 0.043 13.1 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Not1 PF04054.10 EMR68870.1 - 1.1e-81 274.6 0.0 4.2e-81 272.7 0.0 1.9 1 1 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EMR68870.1 - 2e-49 167.0 4.1 4.8e-49 165.8 2.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Methyltransf_23 PF13489.1 EMR68871.1 - 1.4e-12 47.5 0.0 2.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR68871.1 - 8.6e-07 29.3 0.0 0.00048 20.5 0.0 3.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR68871.1 - 0.0028 18.1 0.0 2.7 8.5 0.0 3.2 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR68871.1 - 0.02 15.4 0.0 0.12 12.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EMR68871.1 - 0.07 12.7 0.0 14 5.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMR68871.1 - 0.1 12.9 0.0 0.33 11.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain DUF4337 PF14235.1 EMR68871.1 - 0.51 10.1 4.0 3 7.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Sugar_tr PF00083.19 EMR68872.1 - 2.2e-25 89.1 9.1 4.7e-16 58.4 0.1 3.6 3 1 1 4 4 4 3 Sugar (and other) transporter NIF PF03031.13 EMR68873.1 - 4.4e-22 78.4 0.0 5.9e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF869 PF05911.6 EMR68874.1 - 0.00017 20.0 5.9 0.00023 19.5 4.1 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Shugoshin_N PF07558.6 EMR68874.1 - 0.011 15.4 0.5 0.027 14.1 0.4 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region OmpH PF03938.9 EMR68874.1 - 0.12 12.3 4.9 0.2 11.5 3.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4164 PF13747.1 EMR68874.1 - 0.69 10.0 5.8 0.66 10.1 1.8 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Jnk-SapK_ap_N PF09744.4 EMR68874.1 - 1.4 8.9 10.1 0.46 10.4 4.3 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 IncA PF04156.9 EMR68874.1 - 4.8 6.7 13.7 13 5.3 8.4 2.2 1 1 0 1 1 1 0 IncA protein TPR_MLP1_2 PF07926.7 EMR68874.1 - 7.5 6.3 16.8 95 2.7 11.7 2.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Glyco_hydro_43 PF04616.9 EMR68875.1 - 5.5e-53 179.9 3.3 6.8e-53 179.5 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PSGP PF07276.6 EMR68875.1 - 0.0013 18.7 0.6 0.0035 17.3 0.4 1.7 1 0 0 1 1 1 1 Apopolysialoglycoprotein (PSGP) HSP70 PF00012.15 EMR68876.1 - 1.2e-06 26.7 0.1 1.5e-05 23.1 0.0 2.3 3 0 0 3 3 3 2 Hsp70 protein ABC1 PF03109.11 EMR68877.1 - 9.1e-33 112.7 0.0 1.6e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 EMR68877.1 - 0.077 12.1 0.0 7.5 5.6 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Init_tRNA_PT PF04179.7 EMR68878.1 - 4.6e-137 457.5 0.0 1.4e-117 393.3 0.0 2.0 1 1 1 2 2 2 2 Initiator tRNA phosphoribosyl transferase Humanin PF15040.1 EMR68878.1 - 0.43 9.8 2.1 1.1 8.5 1.4 1.6 1 0 0 1 1 1 0 Humanin family DUF4201 PF13870.1 EMR68879.1 - 0.003 17.0 3.7 0.003 17.0 2.5 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4201) TMPIT PF07851.8 EMR68879.1 - 0.0042 16.2 2.4 0.0067 15.5 1.7 1.3 1 0 0 1 1 1 1 TMPIT-like protein Spc7 PF08317.6 EMR68879.1 - 0.007 15.0 5.4 0.012 14.3 3.8 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Not3 PF04065.10 EMR68879.1 - 0.007 15.6 5.1 0.016 14.4 3.1 1.9 1 1 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component FliJ PF02050.11 EMR68879.1 - 0.015 15.3 5.0 0.1 12.6 4.0 2.1 2 1 0 2 2 2 0 Flagellar FliJ protein YlqD PF11068.3 EMR68879.1 - 0.021 14.8 3.8 0.049 13.6 2.6 1.6 1 0 0 1 1 1 0 YlqD protein DUF1217 PF06748.7 EMR68879.1 - 0.04 14.0 0.5 0.15 12.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1217) Snapin_Pallidin PF14712.1 EMR68879.1 - 0.058 13.7 1.1 0.058 13.7 0.7 2.4 3 0 0 3 3 2 0 Snapin/Pallidin Reo_sigmaC PF04582.7 EMR68879.1 - 0.33 10.0 2.5 0.85 8.7 0.8 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Pox_A_type_inc PF04508.7 EMR68879.1 - 0.4 10.5 4.3 0.34 10.8 0.7 2.7 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat Fib_alpha PF08702.5 EMR68879.1 - 0.7 9.9 7.1 0.39 10.8 3.3 1.9 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family DUF2968 PF11180.3 EMR68879.1 - 1.1 8.5 12.3 5.4 6.3 4.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Rabaptin PF03528.10 EMR68879.1 - 1.3 8.9 7.8 1.2 9.1 3.7 2.1 2 0 0 2 2 2 0 Rabaptin Seryl_tRNA_N PF02403.17 EMR68879.1 - 6.6 6.8 8.5 10 6.1 3.5 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FlxA PF14282.1 EMR68879.1 - 6.7 6.7 9.7 3.2 7.7 3.2 2.5 1 1 1 2 2 2 0 FlxA-like protein DUF947 PF06102.7 EMR68880.1 - 9.8e-51 171.9 12.2 9.8e-51 171.9 8.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF947) Sigma70_ner PF04546.8 EMR68880.1 - 3.1 7.3 23.8 2.7 7.5 8.6 2.6 2 1 0 2 2 2 0 Sigma-70, non-essential region DNA_pol_phi PF04931.8 EMR68880.1 - 7 4.2 18.5 10 3.7 12.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi KOW PF00467.24 EMR68884.1 - 0.0001 21.9 0.4 0.00024 20.6 0.3 1.7 1 0 0 1 1 1 1 KOW motif Ras PF00071.17 EMR68886.1 - 2.2e-45 153.9 0.0 2.7e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR68886.1 - 2.4e-09 37.7 0.0 4.4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein DUF4066 PF13278.1 EMR68887.1 - 3.5e-14 52.4 0.0 5e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EMR68887.1 - 1e-05 25.0 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Hce2 PF14856.1 EMR68888.1 - 3.4e-17 62.1 1.0 5.1e-17 61.5 0.7 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DEAD PF00270.24 EMR68890.1 - 2e-48 164.0 0.0 7.2e-46 155.7 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR68890.1 - 2.3e-28 97.8 0.0 3.4e-27 94.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EMR68890.1 - 0.0073 15.3 0.0 0.0073 15.3 0.0 4.2 2 1 2 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit MIP-T3 PF10243.4 EMR68890.1 - 0.071 11.5 38.6 0.095 11.1 26.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 LMBR1 PF04791.11 EMR68890.1 - 0.35 9.3 5.2 0.53 8.7 3.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein SOBP PF15279.1 EMR68890.1 - 2.9 8.2 15.6 4.8 7.4 10.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Daxx PF03344.10 EMR68890.1 - 4.1 5.7 29.3 5.8 5.2 20.3 1.2 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 EMR68890.1 - 5.8 4.4 19.0 8.8 3.8 13.1 1.3 1 0 0 1 1 1 0 Ycf1 NifU_N PF01592.11 EMR68891.1 - 5.3e-52 175.0 0.0 7.4e-52 174.6 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain GTP_EFTU PF00009.22 EMR68892.1 - 8.4e-49 165.5 0.0 1.4e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EMR68892.1 - 1.6e-37 127.7 6.3 2.5e-37 127.0 4.4 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EMR68892.1 - 1.9e-17 62.9 0.0 3.6e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EMR68892.1 - 3.9e-05 23.6 0.1 0.00012 22.1 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMR68892.1 - 6.8e-05 22.7 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 EMR68892.1 - 0.00011 22.0 0.0 0.00032 20.5 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.17 EMR68892.1 - 0.00013 21.3 0.0 0.00051 19.4 0.0 1.9 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 EMR68892.1 - 0.033 13.4 0.0 0.1 11.8 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EMR68893.1 - 1.3e-12 47.8 0.0 5.6e-12 45.7 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EMR68893.1 - 7.4e-07 29.1 0.0 0.001 18.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EMR68893.1 - 7e-05 22.0 0.0 0.00081 18.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 IIGP PF05049.8 EMR68893.1 - 0.00017 20.5 0.0 0.00058 18.7 0.0 1.9 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EMR68893.1 - 0.00026 21.3 0.0 0.0017 18.6 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 EMR68893.1 - 0.0022 18.0 1.0 0.01 15.8 0.0 2.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 EMR68893.1 - 0.016 14.6 0.1 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EMR68893.1 - 0.031 14.7 0.0 0.082 13.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Septin PF00735.13 EMR68893.1 - 0.062 12.3 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Septin AIG1 PF04548.11 EMR68893.1 - 0.085 11.9 0.0 0.21 10.6 0.0 1.7 1 1 0 1 1 1 0 AIG1 family UCH PF00443.24 EMR68894.1 - 4.6e-42 143.9 0.0 7.2e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EMR68894.1 - 4.5e-23 80.4 0.1 2.7e-11 42.9 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.14 EMR68894.1 - 5.8e-22 77.5 14.7 4e-19 68.4 1.2 3.1 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EMR68894.1 - 3e-14 53.1 0.0 1.6e-11 44.2 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rft-1 PF04506.8 EMR68895.1 - 4.1e-80 269.6 0.6 2e-64 217.9 0.0 2.7 2 1 0 2 2 2 2 Rft protein HORMA PF02301.13 EMR68896.1 - 1e-45 155.8 0.0 1.2e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Stirrup PF09061.1 EMR68896.1 - 0.02 14.8 0.0 0.078 12.8 0.0 1.8 2 0 0 2 2 2 0 Stirrup MSA-2c PF12238.3 EMR68896.1 - 0.057 13.0 0.7 0.086 12.4 0.5 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Anp1 PF03452.9 EMR68897.1 - 5.2e-117 389.7 0.0 9.6e-117 388.9 0.0 1.4 1 0 0 1 1 1 1 Anp1 FAD_binding_4 PF01565.18 EMR68898.1 - 7.7e-10 38.3 0.3 1.4e-09 37.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 EMR68898.1 - 8.6e-10 38.6 2.5 8.6e-10 38.6 1.7 2.1 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase Streptin-Immun PF11083.3 EMR68899.1 - 0.019 14.9 0.3 0.031 14.2 0.1 1.4 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Sec7 PF01369.15 EMR68900.1 - 1.7e-60 203.9 0.3 3.6e-60 202.8 0.2 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EMR68900.1 - 8.2e-19 67.6 0.2 9.6e-11 41.3 0.0 3.7 3 0 0 3 3 3 3 Guanine nucleotide exchange factor in Golgi transport N-terminal Glyco_hydro_61 PF03443.9 EMR68901.1 - 0.00085 19.1 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Serglycin PF04360.7 EMR68901.1 - 0.0029 17.3 11.5 0.081 12.6 1.3 2.3 2 0 0 2 2 2 2 Serglycin Chitin_bind_3 PF03067.10 EMR68901.1 - 0.015 15.6 0.8 0.027 14.7 0.0 1.9 3 0 0 3 3 3 0 Chitin binding domain adh_short PF00106.20 EMR68902.1 - 5.6e-17 62.1 0.8 3.8e-15 56.1 0.6 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR68902.1 - 1.1e-15 58.1 0.1 2.1e-13 50.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR68902.1 - 2.2e-07 30.7 0.0 3.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR68902.1 - 2.4e-05 23.9 0.2 0.00046 19.6 0.1 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR68902.1 - 0.00049 20.1 0.8 0.001 19.1 0.5 1.5 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMR68902.1 - 0.00086 18.0 0.4 0.0012 17.5 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EMR68902.1 - 0.004 17.1 0.5 0.0065 16.4 0.3 1.3 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EMR68902.1 - 0.018 14.0 0.4 0.028 13.3 0.2 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EMR68902.1 - 0.18 11.4 1.2 0.33 10.5 0.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CDC45 PF02724.9 EMR68903.1 - 0.75 7.7 2.4 1 7.2 1.6 1.1 1 0 0 1 1 1 0 CDC45-like protein MRI PF15325.1 EMR68903.1 - 1.9 9.5 10.3 12 6.9 7.2 2.4 1 0 0 1 1 1 0 Modulator of retrovirus infection Daxx PF03344.10 EMR68903.1 - 5.6 5.3 12.4 9.4 4.5 8.6 1.3 1 0 0 1 1 1 0 Daxx Family GDA1_CD39 PF01150.12 EMR68904.1 - 4.2e-104 348.4 0.0 5.9e-104 347.9 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family p450 PF00067.17 EMR68905.1 - 1e-48 166.0 0.0 1.5e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M19 PF01244.16 EMR68906.1 - 1.2e-92 310.3 0.0 1.4e-92 310.1 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) tRNA-synt_His PF13393.1 EMR68907.1 - 6.5e-39 133.8 0.0 1.6e-38 132.5 0.0 1.7 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EMR68907.1 - 3.8e-15 55.9 0.0 1.3e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMR68907.1 - 3e-08 33.4 0.0 1.3e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EMR68907.1 - 7.3e-05 21.6 0.0 0.0048 15.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) Glyco_hydro_42 PF02449.10 EMR68909.1 - 2.1e-105 352.9 2.7 2.6e-105 352.6 1.9 1.1 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.5 EMR68909.1 - 1.6e-30 105.8 0.0 2.5e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Glyco_hydro_14 PF01373.12 EMR68909.1 - 0.00037 19.3 0.1 0.00057 18.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Glyco_hydro_42C PF08533.5 EMR68909.1 - 0.0014 18.1 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain Cellulase-like PF12876.2 EMR68909.1 - 0.0076 16.6 0.2 1.4 9.4 0.0 2.6 1 1 1 2 2 2 1 Sugar-binding cellulase-like Cellulase PF00150.13 EMR68909.1 - 0.0095 15.1 0.3 0.14 11.3 0.1 2.1 1 1 1 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DSPc PF00782.15 EMR68910.1 - 4.5e-12 45.6 0.1 6.6e-07 28.9 0.1 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Ank_4 PF13637.1 EMR68911.1 - 0.0011 19.3 0.1 0.0081 16.6 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMR68911.1 - 0.0021 18.3 0.1 0.0046 17.2 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMR68911.1 - 0.099 12.9 0.3 0.56 10.5 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Glyco_hydro_18 PF00704.23 EMR68912.1 - 3.9e-51 174.5 0.1 5.1e-51 174.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EMR68912.1 - 0.00025 20.9 32.8 0.039 13.9 9.8 2.7 2 0 0 2 2 2 2 Chitin recognition protein Peptidase_S8 PF00082.17 EMR68913.1 - 3.8e-09 36.0 0.1 5.3e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Polysacc_synt_C PF14667.1 EMR68914.1 - 0.00071 19.3 0.4 0.00071 19.3 0.3 4.2 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain MatE PF01554.13 EMR68914.1 - 0.00076 19.1 20.8 0.0031 17.1 0.9 3.6 3 1 0 3 3 3 2 MatE DUF647 PF04884.9 EMR68915.1 - 9.4e-90 300.1 8.2 3.4e-50 170.5 0.1 2.1 1 1 1 2 2 2 2 Vitamin B6 photo-protection and homoeostasis Metallophos PF00149.23 EMR68916.1 - 4.5e-05 22.9 3.5 0.01 15.2 2.4 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase zf-C2H2_4 PF13894.1 EMR68917.1 - 0.7 10.3 3.6 20 5.7 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger FMO-like PF00743.14 EMR68918.1 - 5.1e-30 104.1 0.0 8.2e-21 73.7 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMR68918.1 - 2.2e-12 47.4 0.0 1.2e-11 45.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR68918.1 - 1.1e-05 25.2 0.5 0.00017 21.3 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EMR68918.1 - 5.9e-05 23.0 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR68918.1 - 0.00016 21.5 0.0 1.2 8.9 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR68918.1 - 0.0013 17.7 0.1 0.24 10.3 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EMR68918.1 - 0.0066 14.9 0.2 0.011 14.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EMR68918.1 - 0.012 14.7 0.3 0.25 10.3 0.1 2.3 2 0 0 2 2 2 0 Thi4 family DAO PF01266.19 EMR68918.1 - 0.016 14.0 1.0 0.092 11.6 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase OCD_Mu_crystall PF02423.10 EMR68918.1 - 0.062 12.0 0.1 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family N2227 PF07942.7 EMR68919.1 - 1e-91 306.6 0.0 7.9e-91 303.7 0.0 1.9 1 1 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EMR68919.1 - 9.8e-06 25.3 0.2 3.7e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR68919.1 - 0.00095 19.6 0.3 0.0035 17.7 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR68919.1 - 0.033 14.6 1.1 0.061 13.8 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain B56 PF01603.15 EMR68920.1 - 4e-175 582.3 6.2 4.7e-175 582.0 4.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Dynamin_N PF00350.18 EMR68920.1 - 0.068 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Dynamin family BUD22 PF09073.5 EMR68921.1 - 0.32 10.0 24.0 0.37 9.8 16.6 1.1 1 0 0 1 1 1 0 BUD22 Nitroreductase PF00881.19 EMR68922.1 - 2.2e-14 53.6 0.0 2.9e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family PV-1 PF06637.6 EMR68923.1 - 0.038 12.5 8.5 0.05 12.1 5.9 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) WEMBL PF05701.6 EMR68923.1 - 0.057 11.8 6.0 0.079 11.4 4.2 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light FUSC PF04632.7 EMR68923.1 - 4.3 5.6 7.3 5.5 5.2 5.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Asparaginase PF00710.15 EMR68924.1 - 4.6e-99 331.2 0.0 7e-99 330.6 0.0 1.2 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EMR68924.1 - 2e-14 53.6 1.1 1.5e-11 44.5 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMR68924.1 - 1.5e-10 40.3 0.0 0.1 12.4 0.0 4.1 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EMR68924.1 - 7.5e-10 39.0 0.2 0.0011 19.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR68924.1 - 6.2e-06 26.2 0.6 0.3 11.3 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR68924.1 - 0.0034 17.4 0.1 3.6 8.1 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat HEAT_EZ PF13513.1 EMR68925.1 - 3e-30 103.9 17.6 2.9e-13 49.8 0.0 11.1 9 2 4 13 13 11 6 HEAT-like repeat HEAT PF02985.17 EMR68925.1 - 4.5e-30 101.0 8.4 6.2e-05 22.7 0.0 10.8 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.1 EMR68925.1 - 3.2e-28 97.8 4.5 7e-07 29.4 0.0 8.8 3 3 6 9 9 9 7 HEAT repeats Cnd1 PF12717.2 EMR68925.1 - 9.8e-13 48.3 0.5 0.21 11.4 0.0 6.6 4 2 2 6 6 6 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EMR68925.1 - 7.4e-11 42.3 0.7 0.1 12.9 0.0 6.4 5 1 2 7 7 7 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EMR68925.1 - 1.7e-09 36.8 5.5 4.8e-05 22.2 0.1 4.9 4 1 0 4 4 4 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 EMR68925.1 - 1.1e-06 28.1 0.2 0.74 9.1 0.0 5.9 5 1 1 6 6 6 2 CLASP N terminal Adaptin_N PF01602.15 EMR68925.1 - 5.2e-06 25.0 0.4 0.012 13.9 0.1 2.9 3 0 0 3 3 3 2 Adaptin N terminal region Arm PF00514.18 EMR68925.1 - 2.6e-05 23.8 6.1 0.76 9.7 0.0 7.4 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 EMR68925.1 - 0.00036 20.3 0.7 0.012 15.4 0.1 3.8 3 1 0 3 3 3 1 Importin-beta N-terminal domain DUF3437 PF11919.3 EMR68925.1 - 0.006 16.2 0.0 0.1 12.3 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) DUF1546 PF07571.8 EMR68925.1 - 0.056 13.5 0.0 30 4.8 0.0 4.4 4 2 0 4 4 4 0 Protein of unknown function (DUF1546) RIX1 PF08167.7 EMR68925.1 - 0.11 12.1 1.7 6.4 6.4 0.0 4.3 5 1 0 5 5 5 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.11 EMR68925.1 - 1.1 9.9 7.0 43 4.9 0.0 5.3 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Guanylate_cyc PF00211.15 EMR68926.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain PS_Dcarbxylase PF02666.10 EMR68927.1 - 6e-78 260.7 0.0 2.6e-77 258.6 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase DUF2741 PF10890.3 EMR68927.1 - 0.16 12.1 0.0 0.46 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2741) IF3_C PF00707.17 EMR68928.1 - 1.2e-09 37.7 0.0 2.4e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EMR68928.1 - 8e-06 25.3 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial translation initiation factor XAP5 PF04921.9 EMR68928.1 - 0.081 12.4 2.3 0.15 11.6 1.6 1.5 1 0 0 1 1 1 0 XAP5, circadian clock regulator FAM176 PF14851.1 EMR68928.1 - 0.23 11.1 3.8 0.13 11.9 1.0 1.8 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.9 EMR68928.1 - 0.27 9.2 2.8 0.41 8.6 1.9 1.3 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.3 EMR68928.1 - 0.34 10.7 10.9 0.4 10.5 6.4 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 AF1Q PF15017.1 EMR68928.1 - 0.54 10.1 9.5 1.3 8.9 6.6 1.6 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Nucleoplasmin PF03066.10 EMR68928.1 - 0.83 9.1 12.9 1.3 8.5 8.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EMR68928.1 - 1.1 8.4 3.7 1.7 7.8 2.5 1.3 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 EMR68928.1 - 1.2 8.8 5.4 2.8 7.7 3.8 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Paf1 PF03985.8 EMR68928.1 - 2.8 6.6 10.2 0.31 9.7 4.0 1.6 2 0 0 2 2 2 0 Paf1 DUF2457 PF10446.4 EMR68928.1 - 3.5 6.2 14.8 0.87 8.2 7.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF4243 PF14027.1 EMR68929.1 - 8.2e-74 248.9 0.7 1e-73 248.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) adh_short PF00106.20 EMR68930.1 - 3.2e-25 88.9 10.3 4.5e-25 88.4 7.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR68930.1 - 2.1e-20 73.5 0.4 2.9e-20 73.0 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR68930.1 - 7.4e-09 35.5 4.6 1.2e-08 34.8 3.2 1.3 1 0 0 1 1 1 1 KR domain Arm PF00514.18 EMR68931.1 - 2e-66 217.7 31.6 1.4e-13 50.0 0.1 11.1 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EMR68931.1 - 1.9e-21 76.1 11.4 1.8e-07 31.3 0.3 6.8 3 2 1 5 5 5 4 HEAT repeats HEAT PF02985.17 EMR68931.1 - 1.1e-14 53.0 17.6 0.015 15.2 0.0 8.7 10 0 0 10 10 9 4 HEAT repeat HEAT_EZ PF13513.1 EMR68931.1 - 3.3e-14 52.8 12.0 0.00041 20.7 0.2 7.7 4 1 5 9 9 9 4 HEAT-like repeat Adaptin_N PF01602.15 EMR68931.1 - 3.8e-13 48.6 4.8 1.8e-07 29.8 0.1 2.7 2 1 1 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.8 EMR68931.1 - 9.9e-12 44.5 6.5 0.00083 18.5 0.1 3.3 2 1 1 3 3 3 3 Armadillo-like V-ATPase_H_N PF03224.9 EMR68931.1 - 7.9e-09 35.0 0.6 0.00016 20.9 0.2 3.5 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.7 EMR68931.1 - 5.4e-08 31.2 0.6 1.1e-07 30.2 0.4 1.5 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) DUF908 PF06012.7 EMR68931.1 - 0.00038 19.8 1.5 0.49 9.6 0.0 3.8 2 1 2 4 4 4 1 Domain of Unknown Function (DUF908) DUF2454 PF10521.4 EMR68931.1 - 0.0017 17.4 0.4 0.021 13.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) PUL PF08324.6 EMR68931.1 - 0.019 13.7 1.6 0.045 12.5 0.3 2.2 2 0 0 2 2 2 0 PUL domain HEAT_PBS PF03130.11 EMR68931.1 - 0.037 14.4 5.2 77 4.2 0.1 6.0 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 EMR68931.1 - 0.05 13.9 0.0 3.3 8.1 0.0 3.2 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region Vpu PF00558.14 EMR68931.1 - 0.074 12.6 1.2 0.16 11.5 0.1 2.0 2 0 0 2 2 2 0 Vpu protein Exo_endo_phos PF03372.18 EMR68932.1 - 2.4e-17 63.6 0.1 3e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MRF_C1 PF13887.1 EMR68932.1 - 0.071 12.1 0.1 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Tyrosinase PF00264.15 EMR68933.1 - 1.5e-40 139.7 0.1 2.3e-40 139.1 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.11 EMR68934.1 - 1.7e-13 50.0 12.5 2.8e-10 39.4 5.2 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily FANCI_S4 PF14678.1 EMR68934.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 4 TRAM_LAG1_CLN8 PF03798.11 EMR68935.1 - 9.1e-33 113.4 14.5 9.1e-33 113.4 10.0 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EMR68935.1 - 1.5e-22 78.8 0.2 5.2e-22 77.1 0.0 2.0 2 0 0 2 2 2 1 TRAM1-like protein Peptidase_S26 PF10502.4 EMR68937.1 - 3e-05 23.5 0.0 0.015 14.7 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 EMR68937.1 - 0.00025 20.6 0.0 0.0012 18.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase S24-like CBS PF00571.23 EMR68938.1 - 8.1e-22 76.7 5.5 1.7e-11 43.7 0.0 3.7 4 0 0 4 4 4 3 CBS domain NAP PF00956.13 EMR68939.1 - 1.8e-51 174.6 7.1 1.8e-51 174.6 5.0 1.4 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF4611 PF15387.1 EMR68939.1 - 0.18 11.9 18.6 0.38 10.9 2.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 EMR68939.1 - 4.1 6.8 22.0 1.8 8.0 4.0 2.4 2 0 0 2 2 2 0 Nucleoplasmin Glyco_hydro_76 PF03663.9 EMR68940.1 - 3.3e-153 510.4 12.8 3.9e-153 510.2 8.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EMR68940.1 - 0.11 11.5 11.1 0.095 11.7 0.2 3.4 3 1 0 4 4 4 0 Glycosyl Hydrolase Family 88 CD99L2 PF12301.3 EMR68941.1 - 0.0057 16.3 0.2 0.009 15.7 0.1 1.4 1 1 0 1 1 1 1 CD99 antigen like protein 2 DUF4328 PF14219.1 EMR68941.1 - 0.058 12.6 0.0 0.078 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) F-box-like PF12937.2 EMR68942.1 - 0.00011 21.8 0.5 0.00023 20.7 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMR68942.1 - 0.031 13.9 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 F-box domain Glyco_hydro_76 PF03663.9 EMR68943.1 - 4.1e-121 404.8 19.8 5.1e-121 404.5 13.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 adh_short_C2 PF13561.1 EMR68944.1 - 8.3e-33 114.1 0.4 9.8e-33 113.8 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR68944.1 - 9.9e-30 103.6 3.7 1.5e-29 103.0 2.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR68944.1 - 5.2e-13 49.0 1.6 7.3e-13 48.5 1.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR68944.1 - 0.0006 19.8 0.7 0.0016 18.5 0.5 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR68944.1 - 0.0011 18.4 0.0 0.027 13.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EMR68944.1 - 0.035 13.7 0.3 0.31 10.6 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF281 PF03436.8 EMR68945.1 - 0.14 12.2 0.8 5.6 7.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF281) Methyltransf_23 PF13489.1 EMR68946.1 - 4.2e-11 42.8 0.0 6.8e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR68946.1 - 7.7e-09 35.9 0.0 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR68946.1 - 5.2e-07 30.0 0.0 2.1e-06 28.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR68946.1 - 6.5e-05 22.5 0.0 0.00019 21.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR68946.1 - 0.00022 20.4 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMR68946.1 - 0.0049 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR68946.1 - 0.029 14.9 0.0 0.23 12.0 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain adh_short PF00106.20 EMR68947.1 - 1.7e-06 28.0 0.2 3e-06 27.2 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR68947.1 - 1.2e-05 25.2 0.2 1.4e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.14 EMR68947.1 - 0.0027 16.8 0.0 0.0055 15.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.8 EMR68947.1 - 0.003 16.8 0.5 0.0063 15.7 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EMR68947.1 - 0.0041 17.1 0.1 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR68947.1 - 0.011 15.1 0.0 0.033 13.6 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EMR68947.1 - 0.033 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMR68947.1 - 0.063 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.13 EMR68948.1 - 1.2e-14 53.7 0.0 2e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR68948.1 - 2.1e-09 37.1 12.3 3.7e-09 36.3 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2360 PF10152.4 EMR68948.1 - 0.68 10.2 4.9 2.8 8.2 1.5 2.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) ACOX PF01756.14 EMR68949.1 - 2.9e-38 131.1 0.0 8.8e-38 129.5 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EMR68949.1 - 5.3e-29 101.0 0.1 1e-28 100.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EMR68949.1 - 3.8e-11 42.3 1.0 1e-10 40.9 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EMR68949.1 - 9.1e-06 25.8 0.1 0.0025 17.9 0.0 2.9 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain BOP1NT PF08145.7 EMR68950.1 - 4.6e-106 354.3 9.3 7.3e-106 353.6 6.4 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EMR68950.1 - 7.1e-30 101.7 6.7 3.9e-11 42.3 0.3 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EMR68950.1 - 0.21 10.3 0.0 0.69 8.6 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like DUF3312 PF11768.3 EMR68950.1 - 0.23 9.6 0.0 0.44 8.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3312) Peptidase_M43 PF05572.8 EMR68951.1 - 7.5e-14 51.5 0.5 1.5e-13 50.6 0.0 1.7 2 1 1 3 3 3 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EMR68951.1 - 1.4e-07 31.6 0.1 2.4e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EMR68951.1 - 4.2e-06 26.9 0.2 5.8e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMR68951.1 - 7e-06 25.7 0.9 1.3e-05 24.7 0.6 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EMR68951.1 - 0.00064 20.2 0.1 0.0012 19.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EMR68951.1 - 0.0083 15.8 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EMR68951.1 - 0.018 13.9 0.2 0.043 12.6 0.1 1.6 1 0 0 1 1 1 0 Peptidase M66 MFS_1 PF07690.11 EMR68952.1 - 1.2e-35 122.9 19.0 1.2e-35 122.9 13.2 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR68952.1 - 1.2e-09 36.9 11.2 1.7e-09 36.4 7.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4407 PF14362.1 EMR68952.1 - 9 5.1 8.3 1 8.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) F-box-like PF12937.2 EMR68953.1 - 7.8e-10 38.3 0.5 2.4e-09 36.7 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMR68953.1 - 1.5e-07 30.8 0.1 4.6e-07 29.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EMR68953.1 - 0.00037 20.1 0.0 0.00086 19.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like domain Phostensin PF13914.1 EMR68953.1 - 0.055 13.5 0.2 0.19 11.8 0.1 2.0 2 0 0 2 2 2 0 Phostensin PP1-binding and SH3-binding region Transglut_core PF01841.14 EMR68954.1 - 1.2e-12 47.9 0.1 2.3e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Tox-PL PF15644.1 EMR68954.1 - 0.0077 16.9 0.0 0.031 15.0 0.0 2.0 2 1 0 2 2 2 1 Papain fold toxin 1 TMEM61 PF15105.1 EMR68954.1 - 0.026 14.0 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 TMEM61 protein family DUF553 PF04473.7 EMR68954.1 - 0.13 11.5 0.0 2.1 7.6 0.0 2.6 2 1 0 2 2 2 0 Transglutaminase-like domain DUF3405 PF11885.3 EMR68955.1 - 7.3e-119 397.2 0.1 1e-118 396.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Ank_2 PF12796.2 EMR68956.1 - 3.6e-54 181.0 2.1 4.8e-15 55.6 0.1 4.1 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EMR68956.1 - 5.2e-52 171.1 15.4 4e-07 29.5 0.0 8.3 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.1 EMR68956.1 - 1.1e-40 136.6 10.6 1.1e-10 41.3 0.0 6.6 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR68956.1 - 6.4e-40 134.8 1.0 1.6e-08 34.8 0.0 6.8 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR68956.1 - 6.3e-36 118.8 5.9 2.3e-05 24.1 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Glyco_hyd_65N_2 PF14498.1 EMR68957.1 - 1e-57 195.5 0.0 1.4e-57 195.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain MOR2-PAG1_C PF14225.1 EMR68958.1 - 4.5e-86 288.8 1.5 4.5e-86 288.8 1.0 1.8 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EMR68958.1 - 1.4e-35 122.2 5.5 1.2e-18 66.2 0.0 3.6 3 1 1 4 4 4 3 Cell morphogenesis central region MOR2-PAG1_N PF14222.1 EMR68958.1 - 4e-15 55.5 0.0 7.4e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal Cnd1 PF12717.2 EMR68958.1 - 1 9.2 4.7 2.2 8.1 0.0 3.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Pmp3 PF01679.12 EMR68959.1 - 1.1e-19 69.8 5.1 1.5e-19 69.4 3.5 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DIM1 PF02966.11 EMR68960.1 - 3.9e-71 236.7 0.3 4.4e-71 236.5 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EMR68960.1 - 0.024 14.7 0.4 0.045 13.8 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.15 EMR68960.1 - 0.086 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin RIO1 PF01163.17 EMR68961.1 - 7.8e-42 142.7 0.4 9.4e-30 103.3 0.0 2.5 1 1 2 3 3 3 2 RIO1 family Rio2_N PF09202.6 EMR68961.1 - 4.3e-22 77.9 0.1 1e-18 67.1 0.0 2.7 2 1 0 2 2 2 2 Rio2, N-terminal APH PF01636.18 EMR68961.1 - 4.4e-07 29.8 5.7 0.00087 19.0 2.2 3.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMR68961.1 - 5.7e-06 25.5 0.1 1.2e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BUD22 PF09073.5 EMR68961.1 - 0.0055 15.8 1.2 0.0055 15.8 0.9 2.1 2 0 0 2 2 2 1 BUD22 TraH_2 PF06871.6 EMR68961.1 - 0.074 12.4 0.2 0.074 12.4 0.2 1.6 2 0 0 2 2 2 0 TraH_2 Ins145_P3_rec PF08709.6 EMR68961.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Prothymosin PF03247.9 EMR68961.1 - 7.1 6.8 32.9 1.6 8.8 8.4 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Npa1 PF11707.3 EMR68962.1 - 3.6e-81 272.7 0.0 5.6e-81 272.1 0.0 1.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Arm PF00514.18 EMR68962.1 - 0.043 13.6 0.1 10 6.1 0.0 3.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Alpha_kinase PF02816.13 EMR68963.1 - 4.8e-39 133.9 0.0 6e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Lon_C PF05362.8 EMR68965.1 - 3.6e-64 215.8 0.1 6.4e-64 215.0 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EMR68965.1 - 1.1e-25 90.5 0.0 2.8e-25 89.2 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EMR68965.1 - 9.4e-23 80.8 0.0 1.5e-21 77.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EMR68965.1 - 3.2e-10 39.5 0.1 3.4e-08 33.0 0.0 2.9 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EMR68965.1 - 5.7e-08 32.5 0.0 1.4e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMR68965.1 - 3.7e-06 27.0 0.1 1.3e-05 25.2 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_17 PF13207.1 EMR68965.1 - 1.3e-05 25.9 0.0 4.6e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMR68965.1 - 3.6e-05 22.9 0.2 9.9e-05 21.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EMR68965.1 - 8.1e-05 22.2 0.0 0.0002 20.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR68965.1 - 0.00022 21.3 0.0 0.0056 16.8 0.0 2.9 2 1 0 2 2 1 1 AAA domain AAA_23 PF13476.1 EMR68965.1 - 0.00089 19.6 1.8 0.026 14.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMR68965.1 - 0.00096 18.8 0.2 0.0032 17.1 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EMR68965.1 - 0.0017 17.7 0.0 0.0045 16.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EMR68965.1 - 0.0019 18.1 0.0 0.0072 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EMR68965.1 - 0.0019 16.9 0.2 0.0062 15.3 0.1 1.8 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 EMR68965.1 - 0.0036 17.6 0.0 0.03 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EMR68965.1 - 0.009 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMR68965.1 - 0.0099 15.7 0.0 0.038 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EMR68965.1 - 0.015 15.4 0.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 EMR68965.1 - 0.018 14.7 0.0 0.27 10.8 0.0 2.7 3 0 0 3 3 3 0 NACHT domain Mg_chelatase PF01078.16 EMR68965.1 - 0.034 13.3 0.1 0.12 11.5 0.0 1.9 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI Prefoldin_3 PF13758.1 EMR68965.1 - 0.043 13.5 5.3 0.64 9.8 0.1 3.1 3 0 0 3 3 3 0 Prefoldin subunit Zeta_toxin PF06414.7 EMR68965.1 - 0.051 12.6 0.0 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin FAM91_N PF14647.1 EMR68965.1 - 0.052 12.5 0.1 0.098 11.6 0.1 1.3 1 0 0 1 1 1 0 FAM91 N-terminus Rad17 PF03215.10 EMR68965.1 - 0.13 10.9 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ORF6C PF10552.4 EMR68965.1 - 0.49 10.1 3.2 4 7.1 0.4 2.5 2 0 0 2 2 2 0 ORF6C domain CCDC-167 PF15188.1 EMR68965.1 - 0.63 10.0 3.8 0.55 10.2 0.4 2.6 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 TBPIP PF07106.8 EMR68965.1 - 0.74 9.3 5.1 5.1 6.6 0.4 2.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin_1 PF12718.2 EMR68965.1 - 2.7 7.8 6.8 21 4.9 2.2 2.8 2 1 0 2 2 2 0 Tropomyosin like GAS PF13851.1 EMR68965.1 - 3.8 6.6 6.9 0.24 10.5 0.2 2.3 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Sec1 PF00995.18 EMR68966.1 - 2.1e-104 350.1 0.0 4.7e-99 332.5 0.0 2.0 1 1 1 2 2 2 2 Sec1 family Apo-CIII PF05778.7 EMR68966.1 - 0.043 13.1 0.1 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Peptidase_MA_2 PF13485.1 EMR68966.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily adh_short PF00106.20 EMR68968.1 - 2.1e-13 50.5 0.0 2.4e-12 47.0 0.0 2.4 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 EMR68968.1 - 2.4e-06 27.3 0.3 1.1e-05 25.1 0.0 2.0 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMR68968.1 - 7.5e-06 25.8 0.2 0.00057 19.7 0.0 2.3 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR68968.1 - 2.3e-05 23.9 0.0 3.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR68968.1 - 0.0023 17.9 0.0 0.0062 16.5 0.0 1.7 1 0 0 1 1 1 1 NADH(P)-binding OAD_gamma PF04277.8 EMR68968.1 - 8.3 6.8 7.4 29 5.1 5.1 2.0 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Synaptobrevin PF00957.16 EMR68969.1 - 2e-31 107.4 0.4 2.7e-31 107.0 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EMR68969.1 - 3.7e-21 74.4 0.0 6.5e-21 73.6 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain RRM_1 PF00076.17 EMR68970.1 - 8.1e-21 73.4 0.0 5e-11 42.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR68970.1 - 5e-14 52.0 0.0 1e-07 31.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR68970.1 - 0.057 13.2 0.1 0.97 9.3 0.1 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.15 EMR68971.1 - 3.2e-63 213.1 0.0 4.7e-63 212.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EMR68971.1 - 1.9e-35 121.9 2.0 2.4e-35 121.6 0.2 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EMR68971.1 - 1.3e-12 48.2 0.2 7.6e-06 26.4 0.0 3.3 2 1 1 3 3 3 2 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EMR68971.1 - 0.0084 16.1 0.3 0.033 14.1 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin domain Kdo PF06293.9 EMR68972.1 - 2.3e-06 26.8 0.1 5.3e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EMR68972.1 - 5.3e-06 25.7 0.0 8.8e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Rod_C PF10493.4 EMR68972.1 - 0.16 10.2 0.1 0.22 9.8 0.1 1.1 1 0 0 1 1 1 0 Rough deal protein C-terminal region APH PF01636.18 EMR68972.1 - 1.6 8.3 6.9 2.4 7.8 0.1 2.8 1 1 1 3 3 3 0 Phosphotransferase enzyme family GHMP_kinases_N PF00288.21 EMR68973.1 - 2.1e-18 66.1 0.1 5.1e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EMR68973.1 - 6.1e-08 32.7 0.2 2.2e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal PALP PF00291.20 EMR68974.1 - 1.3e-60 205.2 3.2 1.7e-60 204.8 2.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_1g PF09334.6 EMR68975.1 - 1.1e-106 356.7 0.0 3e-106 355.3 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EMR68975.1 - 2.6e-17 62.0 0.1 1.2e-06 26.8 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMR68975.1 - 2.9e-05 23.8 0.0 5.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EMR68975.1 - 0.00017 20.8 0.0 0.26 10.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain SNF2_N PF00176.18 EMR68976.1 - 3.7e-49 167.1 0.4 5.9e-49 166.4 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMR68976.1 - 1.5e-12 47.2 0.0 3.6e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EMR68976.1 - 1.4e-05 24.6 14.1 2.8e-05 23.6 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMR68976.1 - 0.00043 20.0 13.4 0.00082 19.1 9.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMR68976.1 - 0.0014 18.6 12.7 0.0029 17.6 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMR68976.1 - 0.0016 18.0 11.9 0.0031 17.1 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CCD PF07860.6 EMR68976.1 - 0.044 13.2 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 WisP family C-Terminal Region zf-RING_5 PF14634.1 EMR68976.1 - 0.27 10.9 13.1 0.57 9.9 9.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.2 EMR68976.1 - 0.45 10.6 7.7 1.7 8.7 5.3 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EMR68976.1 - 0.53 10.0 5.8 1.6 8.5 4.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger NAD_binding_9 PF13454.1 EMR68977.1 - 1.6e-08 34.4 0.1 2e-08 34.1 0.1 1.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EMR68977.1 - 4.9e-08 32.8 1.0 6.8e-08 32.4 0.2 1.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR68977.1 - 1.8e-07 31.4 0.4 2.1e-07 31.2 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR68977.1 - 1.5e-05 24.2 0.2 1.5e-05 24.1 0.1 1.0 1 0 0 1 1 1 1 Thi4 family FMO-like PF00743.14 EMR68977.1 - 6.8e-05 21.2 0.0 7.5e-05 21.1 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EMR68977.1 - 0.0045 16.8 0.3 0.0049 16.7 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR68977.1 - 0.01 14.3 1.6 0.013 14.0 1.1 1.1 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 EMR68977.1 - 0.011 14.6 0.5 0.013 14.4 0.4 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMR68977.1 - 0.013 14.6 0.1 0.013 14.5 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 EMR68977.1 - 0.052 13.3 0.1 0.058 13.2 0.0 1.1 1 0 0 1 1 1 0 ThiF family NAD_Gly3P_dh_N PF01210.18 EMR68977.1 - 0.057 13.1 0.2 0.078 12.7 0.1 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amino_oxidase PF01593.19 EMR68977.1 - 0.063 12.3 0.1 0.072 12.1 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 EMR68977.1 - 0.065 13.3 0.1 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 EMR68977.1 - 0.067 11.8 0.3 0.069 11.7 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 EMR68977.1 - 0.091 13.1 0.6 0.14 12.5 0.4 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 EMR68977.1 - 0.11 11.9 0.5 0.12 11.8 0.3 1.1 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Ish1 PF10281.4 EMR68978.1 - 0.0045 17.0 0.1 0.011 15.7 0.1 1.7 1 1 0 1 1 1 1 Putative stress-responsive nuclear envelope protein NTF2 PF02136.15 EMR68979.1 - 0.14 12.5 0.1 0.53 10.6 0.2 1.9 2 1 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain TTSSLRR PF12468.3 EMR68979.1 - 0.82 9.2 5.8 0.43 10.1 1.4 2.3 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein Acetyltransf_3 PF13302.1 EMR68980.1 - 2.4e-15 56.9 0.0 3.6e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR68980.1 - 2.1e-06 27.3 0.1 0.0084 15.8 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_8 PF13523.1 EMR68980.1 - 3.4e-05 23.7 0.0 0.19 11.5 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR68980.1 - 0.00011 22.1 0.1 0.001 19.0 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EMR68980.1 - 0.0018 18.2 0.0 0.043 13.7 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_L38e PF01781.13 EMR68981.1 - 1.1e-33 114.7 2.1 1.4e-33 114.4 1.5 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family LRR_6 PF13516.1 EMR68982.1 - 6.6e-05 22.5 4.6 0.58 10.3 0.0 7.3 8 0 0 8 8 8 1 Leucine Rich repeat LRR_8 PF13855.1 EMR68982.1 - 0.00037 20.1 6.0 6.4 6.6 0.1 5.7 3 2 3 6 6 6 3 Leucine rich repeat LRR_4 PF12799.2 EMR68982.1 - 0.0035 16.9 6.3 0.29 10.7 0.1 5.0 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EMR68982.1 - 0.5 10.7 5.5 80 4.1 0.0 6.0 7 1 0 7 7 7 0 Leucine rich repeat FLO_LFY PF01698.11 EMR68982.1 - 0.54 9.0 7.8 0.84 8.4 5.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein PGA2 PF07543.7 EMR68982.1 - 2.3 7.9 13.2 4.5 7.0 9.2 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Methyltransf_2 PF00891.13 EMR68985.1 - 2.2e-32 112.1 0.0 2.7e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EMR68985.1 - 1.7e-06 28.5 0.0 2.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR68985.1 - 0.00043 20.7 0.0 0.0007 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EMR68985.1 - 0.0044 16.3 0.0 0.0053 16.0 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.4 EMR68985.1 - 0.018 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EMR68985.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PPTA PF01239.17 EMR68986.1 - 6.2e-40 132.9 14.0 2.8e-08 32.7 0.0 6.1 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.1 EMR68986.1 - 0.022 15.3 2.5 2.7 8.8 0.6 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat KIX PF02172.11 EMR68986.1 - 0.025 14.6 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 KIX domain TPR_7 PF13176.1 EMR68986.1 - 0.15 11.9 1.4 0.47 10.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1772 PF08592.6 EMR68987.1 - 2e-25 89.1 5.2 2.9e-25 88.6 3.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) PCI PF01399.22 EMR68988.1 - 2.8e-12 46.8 0.0 3.7e-11 43.2 0.0 2.2 1 1 1 2 2 2 1 PCI domain TPR_11 PF13414.1 EMR68988.1 - 0.039 13.6 0.2 0.11 12.1 0.1 1.8 2 0 0 2 2 2 0 TPR repeat MbeD_MobD PF04899.7 EMR68988.1 - 0.1 12.5 0.2 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 MbeD/MobD like SelP_N PF04592.9 EMR68989.1 - 0.038 13.3 4.1 0.065 12.6 2.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Amidohydro_5 PF13594.1 EMR68990.1 - 6.7e-08 32.2 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EMR68990.1 - 0.00053 20.1 0.0 0.00063 19.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EMR68990.1 - 0.0043 16.7 0.1 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Ribosomal_L18ae PF01775.12 EMR68991.1 - 3.8e-60 201.2 0.6 4.8e-60 200.9 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Spore_YtfJ PF09579.5 EMR68992.1 - 0.65 9.8 6.8 1.2 9.0 4.7 1.4 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) UDG PF03167.14 EMR68994.1 - 7.4e-26 90.4 0.1 1.9e-25 89.0 0.1 1.7 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily Mito_carr PF00153.22 EMR68995.1 - 8.1e-36 121.6 0.2 4.8e-13 48.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Hydantoinase_B PF02538.9 EMR68996.1 - 2.6e-160 534.1 0.0 3.6e-160 533.6 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EMR68996.1 - 1.6e-83 280.1 0.0 4.4e-83 278.7 0.0 1.8 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EMR68996.1 - 1.4e-49 167.9 0.9 1e-47 161.9 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region BTB PF00651.26 EMR68997.1 - 1.1e-09 38.3 0.0 5.5e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 EMR68997.1 - 0.013 15.5 0.0 0.051 13.6 0.0 1.9 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Cpn60_TCP1 PF00118.19 EMR68998.1 - 4.9e-146 487.1 1.7 5.5e-146 486.9 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 EMR68998.1 - 0.15 12.0 1.5 48 3.8 0.0 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain MFS_1 PF07690.11 EMR68999.1 - 2.1e-36 125.3 23.7 2.1e-36 125.3 16.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EMR68999.1 - 2.8e-05 23.8 1.8 0.00046 19.9 0.0 2.9 3 0 0 3 3 3 1 MFS_1 like family DUF1049 PF06305.6 EMR69000.1 - 0.036 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Chromosome_seg PF13889.1 EMR69001.1 - 0.004 17.0 0.1 0.031 14.1 0.0 2.3 2 0 0 2 2 2 1 Chromosome segregation during meiosis NAD_binding_6 PF08030.7 EMR69001.1 - 0.44 10.4 2.0 0.77 9.6 1.4 1.5 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Fungal_trans PF04082.13 EMR69002.1 - 4.1e-17 61.9 0.0 7.1e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR69002.1 - 8.2e-07 28.8 6.6 8.2e-07 28.8 4.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EMR69003.1 - 1.4e-11 43.9 0.1 2.7e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMR69003.1 - 7.4e-05 22.2 0.2 0.00015 21.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 EMR69003.1 - 0.09 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Acetyltransf_3 PF13302.1 EMR69004.1 - 1e-32 113.2 0.0 1.4e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR69004.1 - 0.00056 19.8 0.0 0.91 9.5 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EMR69004.1 - 0.0046 16.8 0.1 0.25 11.2 0.0 2.7 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR69004.1 - 0.023 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.1 EMR69004.1 - 0.093 12.6 0.0 0.65 9.9 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Amidohydro_4 PF13147.1 EMR69005.1 - 1.9e-14 54.3 0.0 2.1e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EMR69005.1 - 3.2e-10 40.1 0.0 5e-10 39.5 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EMR69005.1 - 4e-07 29.5 0.1 1e-06 28.2 0.1 1.7 1 1 0 1 1 1 1 Amidohydrolase family CorA PF01544.13 EMR69006.1 - 0.1 11.6 1.3 0.19 10.7 0.9 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ISG65-75 PF11727.3 EMR69006.1 - 0.2 10.7 7.9 0.35 9.8 5.4 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF1708 PF08101.6 EMR69007.1 - 1.7e-127 425.7 0.0 8.1e-106 354.3 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF1708) Inhibitor_I9 PF05922.11 EMR69008.1 - 0.00045 20.7 0.0 0.00067 20.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3186 PF11382.3 EMR69008.1 - 0.085 11.9 0.1 0.089 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) DIOX_N PF14226.1 EMR69009.1 - 2.9e-27 95.5 0.0 4.7e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMR69009.1 - 4.6e-21 74.9 0.0 1.2e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosom_S12_S23 PF00164.20 EMR69010.1 - 9.4e-41 138.0 0.5 1.1e-40 137.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 GST_N_3 PF13417.1 EMR69011.1 - 2.6e-13 49.9 0.0 4.9e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMR69011.1 - 1.1e-11 44.7 0.0 2.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR69011.1 - 1.6e-10 40.7 0.0 2.6e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMR69011.1 - 3.3e-10 39.8 0.0 6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR69011.1 - 2.1e-05 24.2 0.2 4.6e-05 23.2 0.0 1.6 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR69011.1 - 0.00018 21.8 0.0 0.00026 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HOOK PF05622.7 EMR69012.1 - 1.1e-11 43.3 46.0 1.1e-11 43.3 31.9 3.1 3 0 0 3 3 3 2 HOOK protein Striatin PF08232.7 EMR69012.1 - 1.6e-05 25.2 2.4 1.6e-05 25.2 1.7 5.9 4 2 3 7 7 7 1 Striatin family Cep57_CLD_2 PF14197.1 EMR69012.1 - 0.0053 16.6 2.7 0.0053 16.6 1.9 8.4 7 1 3 10 10 10 3 Centrosome localisation domain of PPC89 HALZ PF02183.13 EMR69012.1 - 0.0086 15.7 2.6 0.0086 15.7 1.8 8.2 7 2 3 10 10 10 1 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 EMR69012.1 - 2.5 7.1 10.1 2.1 7.4 0.1 3.2 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Inhibitor_I71 PF12628.2 EMR69013.1 - 0.64 9.6 5.8 0.067 12.8 0.7 1.7 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor FAD_binding_4 PF01565.18 EMR69014.1 - 5.6e-26 90.6 0.7 9.4e-26 89.9 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR69014.1 - 0.045 13.6 0.4 0.1 12.5 0.3 1.6 1 0 0 1 1 1 0 Berberine and berberine like MFS_1 PF07690.11 EMR69015.1 - 6.1e-41 140.2 46.9 1.4e-40 139.1 32.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR69015.1 - 1.9e-12 46.1 11.9 2.9e-12 45.6 8.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMR69015.1 - 1.6e-09 36.8 8.5 1.6e-09 36.8 5.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter UbiA PF01040.13 EMR69016.1 - 1.6e-30 106.2 19.0 2.3e-30 105.7 13.2 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4079 PF13301.1 EMR69016.1 - 0.023 14.7 0.2 0.051 13.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) CENP-T PF15511.1 EMR69017.1 - 2 7.5 12.1 2.4 7.3 8.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 EMR69017.1 - 9.9 4.5 18.7 10 4.4 13.0 1.1 1 0 0 1 1 1 0 Daxx Family Grp1_Fun34_YaaH PF01184.14 EMR69018.1 - 1.4e-19 70.2 20.0 1.6e-19 70.0 13.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3096 PF11295.3 EMR69018.1 - 2 7.9 6.5 0.27 10.7 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3096) ADH_N PF08240.7 EMR69020.1 - 1.9e-26 91.9 0.2 4.2e-26 90.8 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR69020.1 - 6.7e-15 54.7 0.6 1.6e-14 53.5 0.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase FAD_binding_2 PF00890.19 EMR69020.1 - 0.00028 19.8 0.9 0.00038 19.4 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EMR69020.1 - 0.012 15.2 1.2 0.27 10.8 0.8 2.4 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EMR69020.1 - 0.015 13.8 1.4 0.022 13.2 1.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.15 EMR69020.1 - 0.017 15.1 0.7 0.05 13.7 0.1 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EMR69020.1 - 0.097 12.5 0.4 1.5 8.6 0.8 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR69020.1 - 0.2 11.6 2.4 0.48 10.4 0.8 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR69020.1 - 0.23 11.4 2.1 0.33 10.9 0.9 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.1 EMR69022.1 - 3.5e-32 111.4 40.8 8.9e-27 93.6 23.4 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EMR69022.1 - 8e-11 40.9 26.1 8e-11 40.9 18.1 1.7 2 0 0 2 2 2 1 Amino acid permease Gram_pos_anchor PF00746.16 EMR69022.1 - 2.4 8.0 0.0 2.4 8.0 0.0 3.4 3 1 1 4 4 4 0 Gram positive anchor Tautomerase_3 PF14832.1 EMR69024.1 - 1e-42 145.3 0.1 1.2e-42 145.1 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Glyco_hydro_30 PF02055.11 EMR69025.1 - 1.4e-31 109.2 0.2 3.3e-30 104.7 0.1 2.0 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EMR69025.1 - 0.012 14.5 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 FAD_binding_4 PF01565.18 EMR69026.1 - 3.5e-17 62.1 5.3 1.9e-15 56.5 3.7 2.4 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR69026.1 - 0.0001 22.1 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Lactamase_B PF00753.22 EMR69027.1 - 4e-21 75.5 0.0 5.9e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMR69027.1 - 9.6e-08 31.7 0.1 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMR69027.1 - 0.051 13.2 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Beta-lactamase superfamily domain HLH PF00010.21 EMR69028.1 - 5.1e-16 58.1 0.1 9.8e-16 57.2 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Uds1 PF15456.1 EMR69028.1 - 0.031 14.2 1.6 0.031 14.2 1.1 2.1 2 0 0 2 2 2 0 Up-regulated During Septation DUF4407 PF14362.1 EMR69028.1 - 0.17 10.8 0.9 0.3 10.0 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DNA_methylase PF00145.12 EMR69028.1 - 0.18 10.9 3.1 0.094 11.8 0.6 1.5 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase Lyase_1 PF00206.15 EMR69029.1 - 2.5e-20 72.8 0.0 3.6e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EMR69029.1 - 6.5e-13 48.5 0.0 2.1e-12 46.8 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Epimerase PF01370.16 EMR69030.1 - 3.4e-15 56.1 0.0 4.5e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMR69030.1 - 2.4e-07 30.8 1.3 4.9e-05 23.3 0.2 3.1 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMR69030.1 - 6.1e-06 26.3 0.1 1e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMR69030.1 - 0.00017 21.2 0.5 0.0011 18.7 0.1 2.2 2 1 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 EMR69030.1 - 0.00078 18.2 0.0 0.0013 17.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMR69030.1 - 0.0022 16.9 0.1 0.0041 16.0 0.1 1.5 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EMR69030.1 - 0.015 14.5 0.1 0.21 10.8 0.0 2.4 3 0 0 3 3 3 0 NmrA-like family Cep57_MT_bd PF06657.8 EMR69032.1 - 7.3e-21 73.9 1.4 7.3e-21 73.9 0.9 6.4 5 2 2 7 7 7 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EMR69032.1 - 1.1e-08 34.9 5.9 1.1e-08 34.9 4.1 7.8 5 2 3 8 8 8 2 Centrosome localisation domain of PPC89 CCDC155 PF14662.1 EMR69032.1 - 0.00027 20.6 19.5 0.00027 20.6 13.5 5.6 2 1 2 5 5 5 1 Coiled-coil region of CCDC155 TBPIP PF07106.8 EMR69032.1 - 0.00065 19.2 12.1 0.00065 19.2 8.4 6.8 3 1 4 7 7 7 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EMR69032.1 - 0.072 12.6 90.2 0.13 11.7 10.5 5.7 3 1 2 5 5 5 0 IncA protein DUF3584 PF12128.3 EMR69032.1 - 0.46 7.7 82.9 1.5 6.0 27.9 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) Mur_ligase_C PF02875.16 EMR69033.1 - 0.0033 17.4 0.0 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Ribonuc_2-5A PF06479.7 EMR69033.1 - 0.09 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease 2-5A Serglycin PF04360.7 EMR69033.1 - 0.16 11.7 0.3 0.43 10.3 0.2 1.7 1 0 0 1 1 1 0 Serglycin DUF1942 PF09167.6 EMR69034.1 - 0.049 13.3 0.1 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) Mur_ligase_M PF08245.7 EMR69035.1 - 0.074 13.1 0.0 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Mur ligase middle domain Methyltransf_23 PF13489.1 EMR69037.1 - 6.2e-22 78.0 0.0 1.1e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR69037.1 - 5.5e-11 42.8 0.0 1e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR69037.1 - 4.9e-10 39.7 0.0 4.6e-09 36.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR69037.1 - 8.1e-10 39.2 0.1 2e-08 34.7 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR69037.1 - 1.4e-08 34.5 0.0 4.2e-07 29.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR69037.1 - 4.2e-06 27.0 0.0 1.7e-05 25.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMR69037.1 - 0.00028 20.9 0.0 0.00057 19.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EMR69037.1 - 0.00055 19.0 0.0 0.00097 18.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EMR69037.1 - 0.02 14.0 0.0 0.35 9.9 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EMR69037.1 - 0.028 13.4 0.0 0.05 12.6 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EMR69037.1 - 0.068 13.1 0.0 0.65 10.0 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain DUF3112 PF11309.3 EMR69039.1 - 9.8e-48 161.9 3.8 2.3e-43 147.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) DUF165 PF02592.10 EMR69039.1 - 1.2 9.3 9.3 1.4 9.0 2.6 3.1 1 1 3 4 4 4 0 Uncharacterized ACR, YhhQ family COG1738 ADH_zinc_N PF00107.21 EMR69040.1 - 6.7e-18 64.4 0.0 9.9e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR69040.1 - 3.8e-07 31.0 0.1 1.4e-06 29.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_2 PF00891.13 EMR69042.1 - 5.9e-29 100.9 0.0 8.5e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EMR69042.1 - 0.012 16.1 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EMR69043.1 - 0.023 14.4 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EMR69043.1 - 0.042 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Mito_fiss_reg PF05308.6 EMR69043.1 - 1.7 7.9 11.9 0.17 11.2 0.8 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator MRI PF15325.1 EMR69043.1 - 3.1 8.7 4.4 2.9 8.9 0.6 2.3 2 0 0 2 2 2 0 Modulator of retrovirus infection CPSF_A PF03178.10 EMR69044.1 - 1e-86 290.9 0.0 8.5e-60 202.5 0.0 3.6 3 1 1 4 4 4 2 CPSF A subunit region MMS1_N PF10433.4 EMR69044.1 - 2.2e-65 220.7 0.0 3.4e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 EMR69044.1 - 0.03 14.2 1.2 0.071 13.0 0.1 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat RE_XcyI PF09571.5 EMR69044.1 - 0.075 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 XcyI restriction endonuclease Ribosomal_L18e PF00828.14 EMR69045.1 - 7.4e-33 113.6 0.1 1e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 ketoacyl-synt PF00109.21 EMR69047.1 - 9.7e-64 215.2 0.1 2e-63 214.2 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EMR69047.1 - 5.7e-57 192.3 0.9 1.4e-56 190.9 0.5 1.9 2 0 0 2 2 1 1 KR domain Acyl_transf_1 PF00698.16 EMR69047.1 - 1.2e-54 185.7 0.0 2e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EMR69047.1 - 9.7e-53 179.2 0.0 1.6e-52 178.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EMR69047.1 - 7.5e-45 152.8 2.7 1.4e-44 151.9 0.4 2.6 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMR69047.1 - 1.1e-37 128.5 0.9 6.3e-37 126.0 0.1 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EMR69047.1 - 2.8e-18 66.2 0.0 1e-17 64.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR69047.1 - 5.6e-12 45.6 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR69047.1 - 1.6e-09 37.5 0.0 5.3e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR69047.1 - 3.6e-09 36.9 0.0 1.5e-08 35.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR69047.1 - 8.2e-08 32.8 0.3 3.3e-07 30.8 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 EMR69047.1 - 2e-07 31.1 0.1 5.2e-07 29.8 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 EMR69047.1 - 2.7e-06 26.6 0.0 5.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 EMR69047.1 - 0.0015 17.9 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Epimerase PF01370.16 EMR69047.1 - 0.026 13.9 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PTSIIB_sorb PF03830.10 EMR69047.1 - 0.048 13.5 0.1 0.2 11.5 0.0 2.1 3 0 0 3 3 3 0 PTS system sorbose subfamily IIB component 3Beta_HSD PF01073.14 EMR69047.1 - 0.078 11.6 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PCMT PF01135.14 EMR69047.1 - 0.15 11.6 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Anp1 PF03452.9 EMR69047.1 - 0.41 9.7 0.0 0.71 8.9 0.0 1.3 1 0 0 1 1 1 0 Anp1 Helicase_C_2 PF13307.1 EMR69048.1 - 9e-54 181.8 0.0 2.3e-53 180.5 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EMR69048.1 - 4.8e-46 156.3 0.0 7.6e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 EMR69048.1 - 0.0021 17.9 0.0 0.51 10.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EMR69048.1 - 0.021 14.9 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF572 PF04502.8 EMR69048.1 - 0.11 11.7 3.2 0.23 10.6 2.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Glyco_transf_28 PF03033.15 EMR69049.1 - 1.8e-25 89.2 0.0 4.3e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 EMR69049.1 - 1.4e-15 56.5 0.0 2.3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 GRAM domain UDPGT PF00201.13 EMR69049.1 - 0.0034 15.9 0.0 0.0074 14.8 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Arylesterase PF01731.15 EMR69050.1 - 9.4e-05 22.3 0.1 0.00018 21.4 0.1 1.5 1 0 0 1 1 1 1 Arylesterase DUF1561 PF07598.6 EMR69050.1 - 0.012 13.5 0.0 0.017 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) Peptidase_S10 PF00450.17 EMR69051.1 - 1.2e-12 47.7 0.0 1.6e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Transferase PF02458.10 EMR69052.1 - 9.7e-17 60.5 0.0 1e-13 50.5 0.0 2.9 2 1 0 2 2 2 2 Transferase family Pkinase PF00069.20 EMR69053.1 - 5.8e-42 143.6 0.0 7.5e-38 130.1 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR69053.1 - 4.1e-13 49.0 0.0 1.1e-06 27.9 0.0 3.8 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.18 EMR69053.1 - 4.5e-06 26.5 0.3 0.0056 16.4 0.1 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EMR69053.1 - 4.9e-06 25.7 0.0 0.0066 15.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EMR69053.1 - 0.029 13.4 0.1 0.42 9.6 0.0 2.7 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3472 PF11958.3 EMR69053.1 - 0.12 12.7 2.9 0.17 12.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3472) DUF3507 PF12015.3 EMR69054.1 - 0.088 12.2 0.0 0.092 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) FAD_binding_3 PF01494.14 EMR69055.1 - 1.5e-22 80.2 0.2 2.1e-13 50.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR69055.1 - 1.5e-07 30.6 0.4 6.4e-05 22.0 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR69055.1 - 1.4e-05 23.8 0.3 0.071 11.5 0.1 2.8 3 0 0 3 3 3 2 HI0933-like protein Trp_halogenase PF04820.9 EMR69055.1 - 3.8e-05 22.4 1.0 6e-05 21.8 0.2 1.5 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.19 EMR69055.1 - 0.0002 20.3 0.9 0.00038 19.4 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMR69055.1 - 0.00046 20.1 0.2 0.0012 18.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR69055.1 - 0.0026 17.6 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR69055.1 - 0.0027 17.7 0.5 0.027 14.5 0.2 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMR69055.1 - 0.0029 16.7 0.4 0.096 11.7 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EMR69055.1 - 0.0098 14.8 0.5 0.074 11.9 0.3 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EMR69055.1 - 0.015 14.3 0.1 0.027 13.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EMR69055.1 - 0.016 15.5 1.7 0.089 13.2 0.2 2.6 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR69055.1 - 0.17 10.7 0.6 0.23 10.2 0.1 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Cnd1_N PF12922.2 EMR69056.1 - 2.6e-55 186.6 0.1 2.6e-55 186.6 0.0 2.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 EMR69056.1 - 1.4e-44 152.0 3.2 1.5e-41 142.2 0.9 3.4 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EMR69056.1 - 8.5e-08 32.3 6.9 0.00075 19.7 0.1 5.6 5 2 1 6 6 6 2 HEAT repeats HEAT PF02985.17 EMR69056.1 - 0.0004 20.2 11.4 0.56 10.4 0.0 6.4 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 EMR69056.1 - 0.001 19.5 5.5 0.16 12.5 0.1 5.5 6 0 0 6 6 6 1 HEAT-like repeat B2 PF11473.3 EMR69056.1 - 0.021 14.3 0.1 0.095 12.3 0.0 2.1 1 0 0 1 1 1 0 RNA binding protein B2 PH PF00169.24 EMR69057.1 - 1.9e-15 56.9 0.3 6.6e-15 55.2 0.0 2.0 2 0 0 2 2 2 1 PH domain GRAM PF02893.15 EMR69057.1 - 6.1e-11 41.6 0.2 1.4e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 GRAM domain PH_11 PF15413.1 EMR69057.1 - 1.4e-05 25.2 0.2 5.4e-05 23.3 0.2 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EMR69057.1 - 5e-05 23.2 0.1 9.8e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EMR69057.1 - 5.2e-05 23.0 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 EMR69057.1 - 0.019 14.9 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Vps36_ESCRT-II PF11605.3 EMR69057.1 - 0.089 12.6 0.4 4.1 7.2 0.0 2.8 3 0 0 3 3 3 0 Vacuolar protein sorting protein 36 Vps36 Fungal_trans PF04082.13 EMR69058.1 - 6.7e-17 61.2 0.1 9.8e-17 60.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Porphobil_deam PF01379.15 EMR69059.1 - 5.6e-80 267.2 0.0 7.3e-80 266.9 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EMR69059.1 - 1.1e-19 70.2 1.6 2.2e-19 69.3 1.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Hap4_Hap_bind PF10297.4 EMR69060.1 - 5.4e-09 35.5 7.1 5.4e-09 35.5 4.9 1.9 2 0 0 2 2 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EMR69060.1 - 1.1e-05 25.3 12.5 9.3e-05 22.3 8.7 2.2 1 1 0 1 1 1 1 bZIP transcription factor CCDC144C PF14915.1 EMR69060.1 - 0.0018 17.2 4.8 0.0027 16.6 3.4 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DUF4618 PF15397.1 EMR69060.1 - 0.0065 15.8 2.0 0.0094 15.3 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) ERM PF00769.14 EMR69060.1 - 0.009 15.5 5.7 0.015 14.8 4.0 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Bacillus_HBL PF05791.6 EMR69060.1 - 0.0091 15.3 0.6 0.015 14.6 0.4 1.2 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) TBPIP PF07106.8 EMR69060.1 - 0.035 13.6 2.6 0.057 12.9 1.8 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Myosin_tail_1 PF01576.14 EMR69060.1 - 0.036 11.7 8.5 0.052 11.2 5.9 1.1 1 0 0 1 1 1 0 Myosin tail RmuC PF02646.11 EMR69060.1 - 0.083 11.7 1.1 0.12 11.1 0.8 1.2 1 0 0 1 1 1 0 RmuC family dsrm PF00035.20 EMR69060.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif PspB PF06667.7 EMR69060.1 - 0.14 12.1 0.4 0.38 10.7 0.2 1.8 1 1 1 2 2 2 0 Phage shock protein B IncA PF04156.9 EMR69060.1 - 0.14 11.7 8.1 0.24 10.9 5.6 1.3 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 EMR69060.1 - 0.18 11.6 14.6 22 4.9 10.1 2.6 1 1 0 1 1 1 0 Basic region leucine zipper Ly49 PF08391.5 EMR69060.1 - 0.22 11.6 0.4 0.4 10.8 0.3 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Hpt PF01627.18 EMR69060.1 - 0.25 11.3 4.9 0.72 9.9 3.4 1.7 1 0 0 1 1 1 0 Hpt domain DUF1664 PF07889.7 EMR69060.1 - 0.29 10.9 0.4 0.56 10.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4482 PF14818.1 EMR69060.1 - 0.32 11.6 9.0 0.87 10.2 6.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) Fmp27_WPPW PF10359.4 EMR69060.1 - 0.6 8.4 5.8 0.86 7.9 4.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DivIC PF04977.10 EMR69060.1 - 0.77 9.2 4.5 0.91 9.0 2.3 1.7 1 1 0 1 1 1 0 Septum formation initiator Spc24 PF08286.6 EMR69060.1 - 0.85 9.3 4.3 1.4 8.5 3.0 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4200 PF13863.1 EMR69060.1 - 0.91 9.4 8.9 1.6 8.6 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4407 PF14362.1 EMR69060.1 - 0.92 8.3 4.6 1.4 7.7 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 EMR69060.1 - 2.2 7.2 6.5 3.5 6.5 4.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_Maf PF03131.12 EMR69060.1 - 2.4 8.5 12.3 0.25 11.6 5.3 1.7 2 0 0 2 2 1 0 bZIP Maf transcription factor GAS PF13851.1 EMR69060.1 - 2.8 7.0 7.0 4.3 6.4 4.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 EMR69060.1 - 3 7.4 6.1 6 6.4 4.2 1.5 1 0 0 1 1 1 0 Mnd1 family ADIP PF11559.3 EMR69060.1 - 3.5 7.5 10.7 5.8 6.8 7.4 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EMR69060.1 - 4.5 7.0 9.6 1.6 8.4 2.5 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HemX PF04375.9 EMR69060.1 - 4.8 5.6 8.0 7.2 5.0 5.6 1.1 1 0 0 1 1 1 0 HemX Opi1 PF08618.5 EMR69061.1 - 3.6e-59 200.7 8.7 4.8e-45 154.2 2.9 2.3 1 1 1 2 2 2 2 Transcription factor Opi1 Ras PF00071.17 EMR69062.1 - 1e-31 109.5 0.1 1.3e-31 109.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR69062.1 - 4.3e-21 75.6 0.1 2.3e-20 73.2 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EMR69062.1 - 1.1e-06 27.9 0.0 1.5e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMR69062.1 - 4.8e-05 22.6 0.1 6.4e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.6 EMR69062.1 - 0.034 12.8 0.2 4 5.9 0.0 2.3 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.18 EMR69062.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 EMR69062.1 - 0.082 11.5 1.2 0.19 10.3 0.0 2.1 1 1 2 3 3 3 0 G-protein alpha subunit Gtr1_RagA PF04670.7 EMR69064.1 - 1.6e-72 243.3 0.0 2.2e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EMR69064.1 - 0.0001 21.7 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EMR69064.1 - 0.00042 19.6 0.1 0.00069 18.8 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EMR69064.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain FAD_binding_4 PF01565.18 EMR69065.1 - 1.6e-14 53.5 0.2 2.5e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain tRNA-synt_1c PF00749.16 EMR69066.1 - 1.2e-95 319.8 0.0 1.6e-95 319.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EMR69066.1 - 6.8e-39 133.3 0.1 1.4e-38 132.2 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain HET PF06985.6 EMR69067.1 - 1.4e-11 44.7 0.9 1.6e-11 44.5 0.6 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Toxin_13 PF07822.6 EMR69067.1 - 0.0048 16.7 2.2 0.011 15.6 1.5 1.6 1 1 0 1 1 1 1 Neurotoxin B-IV-like protein Ribonuc_P_40 PF08584.6 EMR69067.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Ribosomal_L1 PF00687.16 EMR69068.1 - 1.6e-19 70.1 0.0 2e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF2688 PF10892.3 EMR69068.1 - 0.0014 18.2 0.0 0.0035 16.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2688) Adeno_PX PF05829.7 EMR69069.1 - 0.061 12.8 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) FAD_binding_4 PF01565.18 EMR69070.1 - 7.3e-18 64.3 1.3 1.4e-17 63.4 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR69070.1 - 1.1e-11 44.3 0.1 2.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EMR69070.1 - 0.0096 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding ATP-synt_B PF00430.13 EMR69072.1 - 0.074 12.8 1.0 0.15 11.8 0.7 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) PMEI PF04043.10 EMR69072.1 - 0.096 12.5 0.1 0.38 10.6 0.0 1.9 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor MerR-DNA-bind PF09278.6 EMR69072.1 - 0.14 12.6 4.4 0.4 11.1 3.0 1.9 1 1 0 1 1 1 0 MerR, DNA binding Vps51 PF08700.6 EMR69072.1 - 0.33 10.8 2.3 0.86 9.4 0.4 2.4 2 1 0 2 2 2 0 Vps51/Vps67 Lyase_1 PF00206.15 EMR69073.1 - 1.9e-91 306.5 0.0 2.4e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EMR69073.1 - 1.3e-25 89.2 0.1 5.9e-25 87.1 0.0 2.2 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Lipase_GDSL_2 PF13472.1 EMR69074.1 - 1e-15 58.3 1.4 1.3e-15 58.0 1.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMR69074.1 - 5.9e-11 42.6 0.3 7.8e-11 42.2 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SGL PF08450.7 EMR69075.1 - 2.9e-06 26.8 0.1 1.6e-05 24.4 0.1 2.1 2 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region COG2 PF06148.6 EMR69076.1 - 3.4e-26 91.6 0.0 7.1e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EMR69076.1 - 4.3e-05 23.2 0.0 0.00014 21.6 0.0 1.9 1 1 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 EMR69076.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF2450 PF10475.4 EMR69076.1 - 0.038 12.8 0.0 0.062 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) MFS_1 PF07690.11 EMR69077.1 - 3.7e-29 101.5 28.5 3.7e-29 101.5 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR69077.1 - 6.6e-14 51.3 7.6 6.6e-14 51.3 5.2 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter ATG22 PF11700.3 EMR69077.1 - 2.6e-08 32.7 15.7 5.2e-08 31.8 6.0 2.9 1 1 1 3 3 3 2 Vacuole effluxer Atg22 like TRI12 PF06609.8 EMR69077.1 - 0.0035 15.6 0.2 0.0057 14.9 0.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FMN_dh PF01070.13 EMR69078.1 - 4.5e-86 288.9 0.6 1.2e-49 169.0 0.1 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 EMR69078.1 - 0.00021 20.3 0.0 0.0006 18.8 0.0 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EMR69078.1 - 0.00023 20.4 0.6 0.00044 19.4 0.4 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 EMR69078.1 - 0.00034 19.6 0.1 0.00051 19.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EMR69078.1 - 0.0013 18.0 0.6 0.054 12.7 0.1 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.16 EMR69078.1 - 0.0014 17.6 0.2 0.13 11.2 0.1 2.3 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase QRPTase_C PF01729.14 EMR69078.1 - 0.0088 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain DUF1851 PF08906.6 EMR69078.1 - 0.049 13.6 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1851) GFO_IDH_MocA PF01408.17 EMR69080.1 - 9.7e-25 87.4 1.1 8e-18 65.0 0.0 3.4 2 1 1 3 3 3 3 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EMR69080.1 - 0.061 13.7 0.1 0.23 11.8 0.1 2.0 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain PNTB PF02233.11 EMR69082.1 - 2.9e-169 563.7 28.2 2.9e-169 563.7 19.6 1.6 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EMR69082.1 - 1e-54 184.5 0.7 1.9e-54 183.7 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EMR69082.1 - 2.9e-48 163.3 0.6 9.1e-48 161.7 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EMR69082.1 - 1.3e-31 108.6 3.6 1.3e-31 108.6 2.5 5.3 5 1 1 6 6 6 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EMR69082.1 - 0.0007 18.7 0.3 0.29 10.2 0.0 3.1 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EMR69082.1 - 0.00087 18.8 1.0 0.0047 16.4 0.1 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EMR69082.1 - 0.016 14.7 0.0 0.062 12.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EMR69082.1 - 0.017 15.6 0.0 0.082 13.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Pyr_redox_2 PF07992.9 EMR69082.1 - 0.019 14.8 0.5 0.05 13.4 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fumerase PF05681.9 EMR69082.1 - 0.025 13.6 0.1 0.048 12.7 0.1 1.4 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) NAD_binding_8 PF13450.1 EMR69082.1 - 0.081 12.9 2.3 0.4 10.7 0.8 2.9 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EMR69082.1 - 1.3 9.1 8.2 9.5 6.3 0.0 4.2 4 1 0 5 5 4 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_1 PF00561.15 EMR69083.1 - 5.5e-27 94.8 0.1 6.1e-26 91.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR69083.1 - 8.3e-24 84.7 1.5 1.6e-23 83.8 1.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR69083.1 - 7.2e-12 45.2 0.0 3.9e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EMR69083.1 - 0.00027 20.7 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 EMR69083.1 - 0.0082 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Adap_comp_sub PF00928.16 EMR69084.1 - 1.6e-90 302.7 0.0 2.3e-90 302.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMR69084.1 - 3e-07 30.2 2.7 9.3e-07 28.6 1.9 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EMR69084.1 - 0.044 12.9 0.0 0.21 10.7 0.0 1.9 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain GCV_H PF01597.14 EMR69085.1 - 3.9e-35 120.1 1.7 4.7e-35 119.9 1.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EMR69085.1 - 0.085 12.5 0.9 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 Biotin-requiring enzyme Sugar_tr PF00083.19 EMR69086.1 - 5.5e-65 219.7 18.6 1.4e-40 139.3 7.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR69086.1 - 2.3e-27 95.6 32.4 1.2e-17 63.7 3.6 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR69086.1 - 0.0011 17.2 3.5 0.0036 15.5 0.0 2.7 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Ni_hydr_CYTB PF01292.15 EMR69086.1 - 5.6 6.3 13.7 1.3 8.3 5.7 2.4 2 1 1 3 3 3 0 Prokaryotic cytochrome b561 Glyco_tranf_2_3 PF13641.1 EMR69087.1 - 1.4e-11 44.5 0.0 2.4e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EMR69087.1 - 1.5e-09 37.4 0.0 0.0015 17.8 0.0 3.4 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EMR69087.1 - 0.0081 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 CRAL_TRIO_N PF03765.10 EMR69087.1 - 0.24 11.5 0.5 0.53 10.4 0.4 1.5 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain PI-PLC-Y PF00387.14 EMR69088.1 - 3.4e-38 130.2 0.1 5.2e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PI-PLC-X PF00388.14 EMR69088.1 - 1.8e-28 98.7 0.1 2.9e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PrcB_C PF14343.1 EMR69088.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 PrcB C-terminal E1-E2_ATPase PF00122.15 EMR69089.1 - 4.7e-50 169.7 2.6 1e-49 168.6 1.8 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMR69089.1 - 2.2e-35 121.8 4.7 2.2e-35 121.8 3.2 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMR69089.1 - 2.1e-32 113.3 0.0 6.1e-31 108.5 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMR69089.1 - 2.2e-17 62.7 0.0 4.6e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMR69089.1 - 3.4e-15 56.7 0.0 8.4e-15 55.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMR69089.1 - 1.3e-11 43.7 0.0 3.4e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2231 PF09990.4 EMR69089.1 - 0.0012 19.1 0.7 0.0012 19.1 0.5 2.9 3 0 0 3 3 3 1 Predicted membrane protein (DUF2231) Hydrolase_3 PF08282.7 EMR69089.1 - 0.013 15.1 2.2 0.013 15.1 0.7 1.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF373 PF04123.8 EMR69089.1 - 0.18 10.8 10.1 0.21 10.5 1.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF373) MFS_1 PF07690.11 EMR69091.1 - 6.6e-27 94.1 29.4 3.7e-25 88.3 20.3 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR69091.1 - 1.2e-07 30.3 12.8 6.5e-07 27.9 6.7 2.6 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMR69091.1 - 0.00011 20.8 9.3 0.00011 20.8 6.5 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter Rick_17kDa_Anti PF05433.10 EMR69092.1 - 0.034 13.8 9.1 0.17 11.5 3.2 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain Pacs-1 PF10254.4 EMR69092.1 - 5.8 5.4 6.6 7.9 4.9 4.6 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein p450 PF00067.17 EMR69093.1 - 7.3e-19 67.6 1.5 2.2e-17 62.7 1.0 2.7 1 1 0 1 1 1 1 Cytochrome P450 Acyl_transf_1 PF00698.16 EMR69094.1 - 1.8e-50 172.1 0.0 3.4e-50 171.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EMR69094.1 - 1.1e-36 125.2 0.1 3.1e-36 123.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EMR69094.1 - 7.9e-30 104.0 0.3 1.4e-29 103.2 0.2 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EMR69094.1 - 1.5e-26 93.1 0.1 3.4e-26 92.0 0.1 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR69094.1 - 2.6e-18 66.4 0.1 9.2e-18 64.7 0.1 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_12 PF08242.7 EMR69094.1 - 3.3e-16 59.5 0.0 8.7e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EMR69094.1 - 4.5e-15 55.3 0.0 1.2e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EMR69094.1 - 2e-12 47.0 0.0 6.2e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR69094.1 - 5e-11 42.4 0.0 1.1e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EMR69094.1 - 6.9e-11 43.1 0.0 2.3e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EMR69094.1 - 4.1e-10 39.7 0.0 1.4e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EMR69094.1 - 4.2e-09 36.9 0.0 1.7e-08 35.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ketoacyl-synt PF00109.21 EMR69094.1 - 6.9e-08 32.2 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_11 PF08241.7 EMR69094.1 - 3.9e-06 27.2 0.0 1.5e-05 25.4 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EMR69094.1 - 2.8e-05 23.6 0.0 0.00055 19.4 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_28 PF02636.12 EMR69094.1 - 0.00066 19.1 0.0 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.6 EMR69094.1 - 0.0026 17.1 0.0 0.0093 15.3 0.0 1.9 1 0 0 1 1 1 1 Nodulation protein S (NodS) ADH_N PF08240.7 EMR69094.1 - 0.0055 16.4 0.1 0.019 14.7 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain RrnaAD PF00398.15 EMR69094.1 - 0.23 10.4 0.0 0.46 9.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF915 PF06028.6 EMR69094.1 - 0.27 10.3 0.0 0.49 9.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) p450 PF00067.17 EMR69095.1 - 6.3e-54 183.2 0.0 8.1e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CP2 PF04516.10 EMR69096.1 - 3.3e-84 281.6 0.0 4.6e-84 281.1 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Phage_G PF02306.10 EMR69096.1 - 0.0085 15.7 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Major spike protein (G protein) Tektin PF03148.9 EMR69096.1 - 0.049 12.1 0.4 0.083 11.4 0.1 1.4 2 0 0 2 2 2 0 Tektin family DUF1996 PF09362.5 EMR69098.1 - 4.1e-85 285.1 0.3 5.1e-85 284.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) ECH PF00378.15 EMR69099.1 - 6.9e-44 149.8 0.2 3.5e-40 137.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family RsbRD_N PF14361.1 EMR69099.1 - 0.18 12.2 0.9 1.7 9.1 0.0 2.6 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain Peptidase_M6 PF05547.6 EMR69100.1 - 2.1e-08 32.6 4.2 0.00035 18.7 1.3 2.2 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 Pyr_redox_3 PF13738.1 EMR69101.1 - 5.9e-22 78.7 0.0 1e-21 77.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR69101.1 - 3.2e-08 33.5 0.0 2e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMR69101.1 - 0.00037 20.4 0.0 0.0022 17.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR69101.1 - 0.007 15.3 0.0 0.037 12.9 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lipase_GDSL PF00657.17 EMR69102.1 - 5.6e-16 59.0 0.2 8.2e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EMR69102.1 - 2e-13 50.8 0.3 2.8e-13 50.4 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EMR69102.1 - 0.0026 17.5 0.0 0.0062 16.3 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Spindle_Spc25 PF08234.7 EMR69103.1 - 0.51 10.3 2.3 18 5.4 0.0 2.7 3 0 0 3 3 3 0 Chromosome segregation protein Spc25 Amidohydro_1 PF01979.15 EMR69105.1 - 3.7 7.1 5.7 3.8 7.0 3.3 1.4 1 1 0 1 1 1 0 Amidohydrolase family Ribonuclease PF00545.15 EMR69106.1 - 1.3e-16 60.3 0.2 1.6e-16 60.0 0.2 1.1 1 0 0 1 1 1 1 ribonuclease GspH PF12019.3 EMR69106.1 - 0.078 13.1 0.2 0.098 12.8 0.2 1.2 1 0 0 1 1 1 0 Type II transport protein GspH Peptidase_S15 PF02129.13 EMR69107.1 - 5.2e-37 127.7 0.7 1.9e-32 112.7 0.1 2.7 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EMR69107.1 - 6.5e-23 81.7 0.0 9.1e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EMR69107.1 - 0.00039 20.3 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR69107.1 - 0.081 12.1 0.1 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMR69107.1 - 0.084 12.6 0.0 0.2 11.4 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ank_2 PF12796.2 EMR69108.1 - 1.2e-26 92.8 0.0 1.9e-17 63.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMR69108.1 - 1.3e-22 79.7 0.2 6.9e-09 35.9 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EMR69108.1 - 1.8e-22 77.9 1.7 9.4e-07 28.3 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EMR69108.1 - 3e-20 71.7 0.2 9.3e-09 35.2 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR69108.1 - 2.1e-16 58.4 0.1 6.5e-05 22.8 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat F-box PF00646.28 EMR69108.1 - 0.0017 17.9 0.1 0.0036 16.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMR69108.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 F-box-like Dioxygenase_C PF00775.16 EMR69110.1 - 6.4e-10 38.5 0.1 1.5e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 Dioxygenase PerC PF06069.6 EMR69110.1 - 0.032 14.2 0.7 0.066 13.2 0.2 1.7 1 1 0 1 1 1 0 PerC transcriptional activator DUF2984 PF11203.3 EMR69110.1 - 0.038 14.0 2.4 0.073 13.1 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2984) adh_short PF00106.20 EMR69111.1 - 1.7e-14 54.0 0.0 2.6e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR69111.1 - 3.4e-07 30.1 0.0 4.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR69111.1 - 3.2e-06 26.7 0.0 3.9e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR69111.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding Antimicrobial_7 PF08102.6 EMR69111.1 - 0.2 11.7 3.1 2.2 8.3 0.0 3.6 4 0 0 4 4 4 0 Scorpion antimicrobial peptide p450 PF00067.17 EMR69112.1 - 3.1e-52 177.6 0.0 3.9e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cys_Met_Meta_PP PF01053.15 EMR69113.1 - 1.2e-120 402.3 0.0 8.3e-110 366.6 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EMR69113.1 - 4.9e-10 38.9 0.0 3.1e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EMR69113.1 - 3.3e-09 36.1 0.0 4.9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMR69113.1 - 4.3e-07 29.0 0.0 8.4e-07 28.0 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMR69113.1 - 2.6e-05 23.4 0.0 6e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 EMR69113.1 - 0.0026 16.3 0.0 0.0038 15.7 0.0 1.1 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GDC-P PF02347.11 EMR69113.1 - 0.011 14.4 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 EMR69113.1 - 0.018 13.3 0.0 0.024 12.9 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase ADH_zinc_N PF00107.21 EMR69113.1 - 0.031 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PrpF PF04303.8 EMR69114.1 - 1.1e-95 320.5 4.4 1.3e-95 320.3 3.0 1.0 1 0 0 1 1 1 1 PrpF protein Abhydrolase_1 PF00561.15 EMR69115.1 - 2.2e-10 40.4 0.0 1.4e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR69115.1 - 0.13 12.0 3.4 0.043 13.6 0.5 1.7 2 1 0 2 2 2 0 Alpha/beta hydrolase family DSBA PF01323.15 EMR69116.1 - 0.00032 20.3 0.0 0.0034 16.9 0.0 1.9 2 0 0 2 2 2 1 DSBA-like thioredoxin domain F_bP_aldolase PF01116.15 EMR69117.1 - 2.1e-54 184.5 0.0 2.3e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Glyco_hydro_61 PF03443.9 EMR69119.1 - 7.6e-05 22.6 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Chitin_bind_3 PF03067.10 EMR69119.1 - 0.0007 19.9 0.0 0.001 19.3 0.0 1.3 1 0 0 1 1 1 1 Chitin binding domain Tox-SGS PF15651.1 EMR69119.1 - 0.081 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Salivary glad secreted protein domain toxin CN_hydrolase PF00795.17 EMR69120.1 - 3.1e-38 130.9 0.1 5.3e-38 130.2 0.0 1.4 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Methyltransf_2 PF00891.13 EMR69121.1 - 2.2e-29 102.3 0.0 3.2e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EMR69121.1 - 0.0015 18.2 0.0 0.0048 16.7 0.0 1.9 1 0 0 1 1 1 1 Dimerisation domain DUF1917 PF08939.5 EMR69122.1 - 7.4e-54 183.0 0.5 1.5e-53 182.0 0.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) Acetyltransf_1 PF00583.19 EMR69123.1 - 3.6e-18 65.3 0.0 5.4e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMR69123.1 - 1.1e-11 44.9 0.1 1.8e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR69123.1 - 1.3e-09 37.7 0.0 1.9e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EMR69123.1 - 7e-09 35.7 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMR69123.1 - 2.7e-08 33.8 0.0 4.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMR69123.1 - 4.4e-07 30.1 0.0 6.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR69123.1 - 9.1e-05 22.3 0.1 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMR69123.1 - 0.0041 16.9 0.1 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Pkinase PF00069.20 EMR69124.1 - 1.5e-74 250.4 0.0 1.9e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR69124.1 - 1.3e-31 109.6 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR69124.1 - 0.00059 18.8 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMR69124.1 - 0.0027 16.8 0.1 0.0045 16.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMR69124.1 - 0.0096 15.6 0.1 0.017 14.8 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Gag_p6 PF08705.6 EMR69124.1 - 0.017 15.1 0.1 0.035 14.1 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.14 EMR69124.1 - 0.054 12.8 0.2 0.19 11.0 0.1 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Seadorna_VP7 PF07387.6 EMR69124.1 - 0.061 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Xpo1 PF08389.7 EMR69125.1 - 4.3e-07 29.9 1.1 3.3e-06 27.0 0.0 2.7 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EMR69125.1 - 0.00016 21.5 0.1 0.00051 19.9 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Pollen_allerg_1 PF01357.16 EMR69125.1 - 0.45 10.3 2.7 1.9 8.3 0.2 2.6 3 0 0 3 3 3 0 Pollen allergen Sec23_trunk PF04811.10 EMR69126.1 - 1.4e-70 237.4 0.0 2.3e-70 236.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EMR69126.1 - 1.3e-23 82.4 0.0 1.6e-22 78.8 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EMR69126.1 - 2e-18 66.6 0.1 4e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EMR69126.1 - 2.3e-17 62.2 5.3 3.8e-17 61.5 3.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EMR69126.1 - 4.9e-10 38.9 0.0 1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Rota_NSP4 PF01452.11 EMR69127.1 - 0.079 12.3 0.2 0.099 11.9 0.2 1.2 1 0 0 1 1 1 0 Rotavirus non structural protein Shisa PF13908.1 EMR69127.1 - 0.092 12.9 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LCAT PF02450.10 EMR69128.1 - 1.4e-95 320.5 0.0 1.7e-95 320.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EMR69128.1 - 0.00048 19.5 0.0 0.00093 18.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) DUF1749 PF08538.5 EMR69128.1 - 0.053 12.4 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) RNA_helicase PF00910.17 EMR69129.1 - 0.0037 17.4 0.0 0.009 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 EMR69129.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.4 EMR69129.1 - 0.017 14.0 0.1 0.053 12.4 0.0 1.8 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EMR69129.1 - 0.029 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 EMR69129.1 - 0.041 13.5 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 EMR69129.1 - 0.08 12.3 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EMR69129.1 - 0.15 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MFS_1 PF07690.11 EMR69130.1 - 2.1e-40 138.5 44.9 1.1e-36 126.2 23.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4185 PF13810.1 EMR69131.1 - 0.09 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) DUF2207 PF09972.4 EMR69131.1 - 2.1 6.8 7.3 2.6 6.5 2.0 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Hemerythrin PF01814.18 EMR69132.1 - 1.3e-11 44.7 0.1 1.5e-11 44.6 0.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Phage_Gp14 PF10666.4 EMR69132.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Phage protein Gp14 Fer4 PF00037.22 EMR69133.1 - 1.4e-13 49.7 16.5 5.6e-08 32.0 2.5 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EMR69133.1 - 6.3e-12 45.6 10.6 1.2e-11 44.7 7.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EMR69133.1 - 4.9e-10 39.5 8.0 9.9e-10 38.5 5.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EMR69133.1 - 1.5e-09 38.4 8.3 0.00018 22.1 0.2 2.6 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 EMR69133.1 - 2.8e-09 36.6 22.0 7.5e-08 32.0 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 EMR69133.1 - 2.1e-08 33.9 31.8 2.1e-05 24.2 8.5 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EMR69133.1 - 1.3e-07 31.0 14.7 0.00046 19.9 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EMR69133.1 - 1.5e-07 31.2 20.8 2.8e-05 24.0 8.2 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 EMR69133.1 - 2.2e-07 30.4 17.1 0.0013 18.5 3.6 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EMR69133.1 - 5.7e-06 26.2 12.7 0.00061 19.9 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EMR69133.1 - 1e-05 25.7 10.1 0.0012 19.1 8.0 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EMR69133.1 - 4.4e-05 23.8 9.8 0.012 16.0 0.4 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EMR69133.1 - 0.0076 16.6 15.1 0.31 11.4 3.2 2.9 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EMR69133.1 - 0.019 15.5 13.2 0.23 12.0 1.1 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EMR69133.1 - 0.079 13.5 16.9 0.17 12.5 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EMR69133.1 - 0.098 12.7 4.6 0.28 11.3 0.1 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Sugar_tr PF00083.19 EMR69135.1 - 9.6e-94 314.4 20.1 1.2e-93 314.2 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR69135.1 - 7.2e-22 77.5 22.4 7.2e-22 77.5 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MIG-14_Wnt-bd PF06664.7 EMR69135.1 - 0.039 12.7 0.6 0.23 10.2 0.4 2.2 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Glyco_hydro_3 PF00933.16 EMR69136.1 - 1.2e-88 296.9 0.0 1.7e-88 296.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR69136.1 - 2.7e-60 203.7 0.7 2.7e-60 203.7 0.5 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR69136.1 - 0.0019 18.1 0.5 0.048 13.5 0.0 2.4 1 1 1 2 2 2 2 Fibronectin type III-like domain NAD_binding_10 PF13460.1 EMR69137.1 - 1.9e-11 44.3 0.1 9.5e-11 42.0 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR69137.1 - 5.5e-06 25.9 0.0 1.6e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR69137.1 - 3e-05 22.8 0.0 4.6e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EMR69137.1 - 0.00011 21.5 0.1 0.0002 20.6 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EMR69137.1 - 0.0025 16.7 0.0 0.0036 16.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EMR69137.1 - 0.034 14.0 0.3 0.091 12.6 0.2 1.7 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.7 EMR69137.1 - 0.14 11.0 0.1 0.48 9.2 0.1 1.9 1 1 0 1 1 1 0 Male sterility protein HET PF06985.6 EMR69138.1 - 7.4e-26 90.9 5.1 7.4e-26 90.9 3.5 3.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TIR_2 PF13676.1 EMR69138.1 - 0.019 15.1 1.4 3.6 7.7 0.7 2.8 2 1 0 2 2 2 0 TIR domain CDC45 PF02724.9 EMR69138.1 - 0.14 10.1 21.9 0.032 12.2 11.5 2.0 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 EMR69138.1 - 0.26 9.1 35.6 0.014 13.3 19.6 2.1 2 0 0 2 2 2 0 Nop14-like family Astro_capsid PF03115.9 EMR69138.1 - 0.3 9.2 6.0 0.51 8.5 4.2 1.4 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Daxx PF03344.10 EMR69138.1 - 1.1 7.6 29.7 2.5 6.4 20.6 1.5 1 0 0 1 1 1 0 Daxx Family VID27 PF08553.5 EMR69138.1 - 4.3 5.4 20.9 8.2 4.5 14.5 1.4 1 0 0 1 1 1 0 VID27 cytoplasmic protein ABM PF03992.11 EMR69139.1 - 3e-09 36.7 0.2 0.00013 21.9 0.0 2.6 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Protoglobin PF11563.3 EMR69140.1 - 1.7e-56 190.2 0.1 2e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Protoglobin Glyco_hydro_61 PF03443.9 EMR69141.1 - 9.3e-39 133.4 0.0 1.1e-38 133.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PP-binding PF00550.20 EMR69142.1 - 1.8e-12 47.3 0.1 2.4e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EMR69142.1 - 1.3e-05 25.1 0.1 1.7e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EMR69142.1 - 0.034 14.2 0.0 0.046 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Sugar_tr PF00083.19 EMR69143.1 - 6.4e-73 245.8 18.1 1e-70 238.5 6.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Beta-lactamase PF00144.19 EMR69143.1 - 8.4e-26 90.7 0.0 1.4e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.11 EMR69143.1 - 2.8e-25 88.7 21.1 4.1e-25 88.2 14.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR69143.1 - 1.8e-07 29.7 1.7 3e-07 29.0 1.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.20 EMR69144.1 - 0.0011 18.2 0.0 0.0024 17.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR69144.1 - 0.0062 15.6 0.0 0.086 11.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Transp_cyt_pur PF02133.10 EMR69145.1 - 9.3e-37 126.6 28.7 1.4e-36 126.0 19.9 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin adh_short PF00106.20 EMR69146.1 - 6.1e-08 32.7 0.0 1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR69146.1 - 5.2e-06 26.2 0.0 7.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR69146.1 - 0.0026 17.2 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR69146.1 - 0.014 14.3 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein NAD_binding_10 PF13460.1 EMR69146.1 - 0.082 12.9 0.0 0.26 11.2 0.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding Nitroreductase PF00881.19 EMR69147.1 - 7.8e-10 38.8 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family LRS4 PF10422.4 EMR69147.1 - 0.15 11.3 0.1 0.2 10.9 0.1 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 FAD_binding_4 PF01565.18 EMR69148.1 - 4.9e-26 90.8 0.1 8.7e-26 90.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR69148.1 - 0.0013 18.5 0.1 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Aldo_ket_red PF00248.16 EMR69149.1 - 5.3e-66 222.3 0.0 6.1e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WSC PF01822.14 EMR69150.1 - 9e-15 54.3 9.6 2e-14 53.2 6.6 1.5 1 0 0 1 1 1 1 WSC domain FAD_binding_4 PF01565.18 EMR69151.1 - 1.1e-29 102.7 0.8 1.8e-29 102.0 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR69151.1 - 0.03 14.2 0.0 0.098 12.5 0.0 1.8 2 0 0 2 2 2 0 Berberine and berberine like GRIM-19 PF06212.7 EMR69152.1 - 1.9e-22 79.3 0.0 3.4e-22 78.5 0.0 1.4 1 1 0 1 1 1 1 GRIM-19 protein p450 PF00067.17 EMR69153.1 - 1.6e-08 33.5 0.0 7.8e-05 21.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 EMR69155.1 - 1.1e-61 208.8 0.0 1.5e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EMR69156.1 - 2.1e-14 52.7 5.7 6.1e-05 22.7 0.0 5.1 5 1 0 5 5 5 3 WD domain, G-beta repeat MFS_1 PF07690.11 EMR69157.1 - 7.1e-42 143.3 36.7 2.7e-41 141.4 13.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily NIF PF03031.13 EMR69158.1 - 7.6e-28 97.1 0.0 1.9e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EMR69158.1 - 1.3e-08 34.5 0.0 3.7e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 twin BRCT domain Biotin_lipoyl PF00364.17 EMR69158.1 - 1.6e-06 27.6 0.1 0.019 14.5 0.0 3.0 3 0 0 3 3 3 2 Biotin-requiring enzyme BRCT PF00533.21 EMR69158.1 - 0.0064 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ribosomal_60s PF00428.14 EMR69158.1 - 0.019 15.3 7.7 0.019 15.3 5.4 4.2 4 0 0 4 4 4 0 60s Acidic ribosomal protein Biotin_lipoyl_2 PF13533.1 EMR69158.1 - 0.065 12.9 2.2 2.4 7.9 0.0 3.7 4 0 0 4 4 4 0 Biotin-lipoyl like Viral_P18 PF04521.8 EMR69158.1 - 0.19 11.2 2.1 0.59 9.5 0.3 2.4 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein adh_short_C2 PF13561.1 EMR69159.1 - 4.9e-30 105.0 0.0 6.2e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR69159.1 - 2.8e-27 95.6 4.7 3.6e-27 95.3 3.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR69159.1 - 2.6e-08 33.7 1.8 4.9e-08 32.8 1.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR69159.1 - 0.00016 21.1 0.1 0.00025 20.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EMR69159.1 - 0.011 15.3 0.7 0.016 14.8 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EMR69159.1 - 0.022 14.7 0.8 0.035 14.1 0.5 1.3 1 0 0 1 1 1 0 NADH(P)-binding Glyco_trans_4_4 PF13579.1 EMR69159.1 - 0.046 13.8 0.1 0.062 13.4 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain NAD_binding_3 PF03447.11 EMR69159.1 - 0.1 13.0 0.1 0.21 12.0 0.0 1.6 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Methyltransf_9 PF08003.6 EMR69160.1 - 0.074 11.7 0.1 0.096 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Vps36_ESCRT-II PF11605.3 EMR69160.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Aldo_ket_red PF00248.16 EMR69161.1 - 6.8e-65 218.7 0.0 7.6e-65 218.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FliG_M PF14841.1 EMR69161.1 - 0.037 14.0 0.1 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 FliG middle domain Glyco_hydro_61 PF03443.9 EMR69162.1 - 1.7e-59 201.3 0.1 2.1e-59 200.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pro_CA PF00484.14 EMR69163.1 - 1.6e-23 83.3 0.5 4.1e-23 82.0 0.0 1.9 2 0 0 2 2 2 1 Carbonic anhydrase Acyl-CoA_dh_2 PF08028.6 EMR69163.1 - 1e-16 61.3 3.8 2.8e-16 59.9 2.6 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMR69163.1 - 3.7e-11 43.5 0.0 1e-10 42.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EMR69163.1 - 5.3e-06 26.5 1.4 1.4e-05 25.2 1.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4278 PF14105.1 EMR69164.1 - 0.0076 16.1 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4278) Pkinase PF00069.20 EMR69165.1 - 7.5e-23 80.9 0.0 1e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR69165.1 - 6.4e-08 31.9 0.0 4.2e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EMR69165.1 - 0.12 11.1 0.1 0.22 10.2 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase COesterase PF00135.23 EMR69166.1 - 6.5e-75 252.8 0.0 7.9e-75 252.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR69166.1 - 1.6e-06 27.8 0.1 8.2e-06 25.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMR69166.1 - 0.0044 16.2 0.0 0.0073 15.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMR69166.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_3 PF00933.16 EMR69168.1 - 1e-82 277.4 0.0 1.5e-82 277.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR69168.1 - 4.7e-53 180.0 0.4 7.1e-53 179.4 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR69168.1 - 2.6e-24 84.9 0.0 4.9e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3292 PF11696.3 EMR69169.1 - 1.6e-213 710.2 0.0 2.9e-212 706.0 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) MtrB PF05440.7 EMR69169.1 - 0.1 12.6 0.0 7.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Methyltransf_2 PF00891.13 EMR69170.1 - 1.3e-05 24.5 0.0 1.6e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase HET PF06985.6 EMR69171.1 - 3.2e-09 37.0 0.0 4.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Myb_DNA-bind_5 PF13873.1 EMR69172.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain ADH_N PF08240.7 EMR69173.1 - 1.6e-19 69.6 3.9 2.7e-19 68.9 2.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR69173.1 - 1.8e-12 46.9 0.0 2.8e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NADH_4Fe-4S PF10589.4 EMR69173.1 - 0.0077 15.3 0.7 0.023 13.8 0.5 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 2-Hacid_dh_C PF02826.14 EMR69173.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3347 PF11827.3 EMR69175.1 - 0.021 14.8 0.4 0.034 14.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) PPR_2 PF13041.1 EMR69175.1 - 0.059 13.3 0.0 0.87 9.6 0.0 2.2 2 0 0 2 2 2 0 PPR repeat family Glyco_hydro_18 PF00704.23 EMR69176.1 - 2.4e-50 171.9 1.0 3.8e-50 171.2 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EMR69176.1 - 9.9e-20 70.1 0.6 8e-06 25.6 0.0 3.6 3 0 0 3 3 3 3 LysM domain eIF-4B PF06273.6 EMR69176.1 - 5.4 5.6 3.6 10 4.7 2.5 1.4 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Melibiase PF02065.13 EMR69177.1 - 1.6e-160 534.1 0.0 1.9e-160 533.8 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 EMR69177.1 - 1e-05 24.5 0.0 1.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 GFO_IDH_MocA PF01408.17 EMR69178.1 - 9e-23 81.0 0.1 2.1e-22 79.9 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMR69178.1 - 1.4e-07 31.2 0.2 8.1e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_7 PF13241.1 EMR69178.1 - 0.0058 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Semialdhyde_dh PF01118.19 EMR69178.1 - 0.0083 16.4 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 EMR69178.1 - 0.095 12.6 0.0 0.26 11.2 0.0 1.8 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PMI_typeI PF01238.16 EMR69179.1 - 1e-71 241.9 0.0 6.4e-71 239.2 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EMR69179.1 - 0.0012 18.3 0.1 0.8 9.2 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Peptidase_S74 PF13884.1 EMR69179.1 - 0.0048 16.9 0.3 0.036 14.1 0.0 2.3 2 0 0 2 2 2 1 Chaperone of endosialidase AraC_binding PF02311.14 EMR69179.1 - 0.017 14.7 0.2 0.14 11.8 0.0 2.4 3 0 0 3 3 3 0 AraC-like ligand binding domain AAA PF00004.24 EMR69181.1 - 1.5e-14 54.3 0.0 2.7e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMR69181.1 - 1.9e-10 41.0 0.0 1.1e-09 38.4 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.13 EMR69181.1 - 1.3e-08 34.6 0.0 2.6e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.1 EMR69181.1 - 2.4e-07 30.9 0.0 5.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMR69181.1 - 0.00019 22.2 0.0 0.0018 19.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EMR69181.1 - 0.0028 17.3 0.2 0.011 15.4 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EMR69181.1 - 0.0032 17.7 0.0 0.0081 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EMR69181.1 - 0.0068 15.4 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EMR69181.1 - 0.013 15.2 0.0 0.12 12.0 0.0 2.3 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EMR69181.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Zot PF05707.7 EMR69181.1 - 0.019 14.4 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_11 PF13086.1 EMR69181.1 - 0.019 14.5 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMR69181.1 - 0.047 13.8 0.0 0.15 12.2 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_32 PF13654.1 EMR69181.1 - 0.049 12.2 0.0 0.076 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMR69181.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EMR69181.1 - 0.12 12.1 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 NTPase WD40 PF00400.27 EMR69182.1 - 6.3e-13 48.0 4.3 0.14 12.1 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat TMF_TATA_bd PF12325.3 EMR69183.1 - 5.7e-42 142.2 11.5 5.7e-42 142.2 7.9 6.4 3 2 3 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EMR69183.1 - 6.3e-16 57.9 11.1 6.3e-16 57.9 7.7 9.4 6 4 3 9 9 9 1 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EMR69183.1 - 0.00046 19.8 5.1 0.00046 19.8 3.5 5.9 2 1 3 5 5 5 1 IncA protein Cortex-I_coil PF09304.5 EMR69183.1 - 0.0032 17.4 5.7 0.0032 17.4 3.9 6.9 2 1 5 7 7 7 2 Cortexillin I, coiled coil HpaB_N PF11794.3 EMR69183.1 - 0.013 14.9 1.1 0.033 13.5 0.8 1.7 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PilO PF04350.8 EMR69183.1 - 0.023 14.6 0.7 0.023 14.6 0.5 5.7 3 1 2 6 6 6 0 Pilus assembly protein, PilO HSBP1 PF06825.7 EMR69183.1 - 0.077 12.5 2.0 5.5 6.6 0.0 3.6 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Tropomyosin_1 PF12718.2 EMR69183.1 - 0.2 11.5 93.6 0.086 12.6 11.6 5.7 3 1 3 6 6 6 0 Tropomyosin like Spc7 PF08317.6 EMR69183.1 - 1.1 7.7 70.5 0.16 10.6 8.2 4.5 3 1 1 4 4 4 0 Spc7 kinetochore protein Prefoldin_2 PF01920.15 EMR69184.1 - 5e-12 45.5 2.3 7.7e-12 44.9 1.4 1.4 1 1 0 1 1 1 1 Prefoldin subunit Myosin_tail_1 PF01576.14 EMR69184.1 - 0.0024 15.7 2.3 0.0031 15.3 1.6 1.0 1 0 0 1 1 1 1 Myosin tail DUF4265 PF14085.1 EMR69184.1 - 0.0078 15.9 0.0 0.016 14.9 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4265) EIF4E-T PF10477.4 EMR69184.1 - 0.012 14.4 0.3 0.013 14.2 0.2 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Myb_Cef PF11831.3 EMR69184.1 - 0.041 13.1 0.5 0.042 13.0 0.4 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component DUF2730 PF10805.3 EMR69184.1 - 0.072 12.8 4.0 0.38 10.5 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) HAUS6_N PF14661.1 EMR69184.1 - 0.098 11.9 0.9 0.11 11.8 0.6 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TMF_TATA_bd PF12325.3 EMR69184.1 - 0.13 12.0 8.3 0.23 11.2 0.1 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.7 EMR69184.1 - 0.16 11.7 3.9 0.25 11.1 2.7 1.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FlxA PF14282.1 EMR69184.1 - 0.57 10.1 9.7 6.4 6.7 3.7 2.1 2 0 0 2 2 2 0 FlxA-like protein TBPIP PF07106.8 EMR69184.1 - 0.77 9.2 5.8 8.7 5.8 4.0 2.0 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 EMR69184.1 - 1.8 8.6 5.8 2.5 8.2 0.1 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family LRR_6 PF13516.1 EMR69185.1 - 1.2e-09 37.2 7.8 0.03 14.3 0.0 6.6 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.2 EMR69185.1 - 5.5e-08 32.2 15.6 0.00033 20.2 0.1 5.6 5 1 0 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EMR69185.1 - 1.2e-06 27.7 0.6 6 7.3 0.0 6.0 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.1 EMR69185.1 - 0.018 14.7 12.4 4.9 6.9 0.1 4.6 3 2 0 3 3 3 0 Leucine rich repeat LRR_7 PF13504.1 EMR69185.1 - 0.041 14.0 1.2 84 4.0 0.0 5.0 5 0 0 5 5 5 0 Leucine rich repeat Dynamin_M PF01031.15 EMR69187.1 - 2.1e-114 381.3 0.0 4.9e-114 380.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EMR69187.1 - 3.1e-54 183.2 2.0 3.6e-54 183.0 0.0 2.1 3 0 0 3 3 3 1 Dynamin family GED PF02212.13 EMR69187.1 - 5.3e-31 106.3 2.6 5.3e-31 106.3 1.8 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EMR69187.1 - 0.0013 18.7 0.1 0.005 16.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMR69187.1 - 0.014 15.8 0.0 0.042 14.3 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein Baculo_p74 PF04583.7 EMR69187.1 - 0.071 12.2 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Baculoviridae p74 conserved region zf-CCHC_4 PF14392.1 EMR69187.1 - 0.15 11.7 0.1 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle UAA PF08449.6 EMR69188.1 - 5.1e-47 160.2 1.0 6.4e-47 159.9 0.7 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EMR69188.1 - 0.032 13.3 0.1 0.055 12.5 0.1 1.4 1 0 0 1 1 1 0 Nucleotide-sugar transporter EamA PF00892.15 EMR69188.1 - 0.032 14.2 8.7 0.6 10.1 2.0 2.3 2 0 0 2 2 2 0 EamA-like transporter family EmrE PF13536.1 EMR69188.1 - 0.034 14.3 1.8 0.034 14.3 1.2 2.3 1 1 1 2 2 2 0 Multidrug resistance efflux transporter 7TMR-DISM_7TM PF07695.6 EMR69188.1 - 0.095 12.3 9.3 0.18 11.4 6.0 1.6 1 1 0 1 1 1 0 7TM diverse intracellular signalling A_deaminase PF00962.17 EMR69189.1 - 2.2e-114 381.8 0.3 2.9e-114 381.4 0.2 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Macoilin PF09726.4 EMR69190.1 - 0.45 8.7 42.5 0.62 8.2 29.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1212 PF06738.7 EMR69190.1 - 2.8 7.3 3.8 2.4 7.5 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1212) IncA PF04156.9 EMR69191.1 - 3.4e-14 52.8 155.6 1.7e-05 24.5 21.3 6.2 1 1 4 5 5 4 4 IncA protein Spc7 PF08317.6 EMR69191.1 - 2.2e-06 26.5 133.1 0.0018 16.9 19.3 6.3 1 1 6 7 7 7 5 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 EMR69191.1 - 2.7e-05 22.1 48.1 2.7e-05 22.1 33.3 3.1 1 1 2 3 3 3 1 Myosin tail DUF869 PF05911.6 EMR69191.1 - 0.00017 20.0 35.5 0.00017 20.0 24.6 4.2 1 1 2 3 3 2 1 Plant protein of unknown function (DUF869) L27 PF02828.11 EMR69191.1 - 0.00018 21.1 10.4 0.44 10.2 0.1 6.0 4 1 0 4 4 4 1 L27 domain AAA_13 PF13166.1 EMR69191.1 - 0.00038 19.0 29.0 0.00038 19.0 20.1 4.1 1 1 3 4 4 4 2 AAA domain GAS PF13851.1 EMR69191.1 - 0.0005 19.3 140.8 0.0011 18.1 14.0 6.8 1 1 6 7 7 7 2 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.15 EMR69191.1 - 0.00064 18.8 53.4 0.00064 18.8 37.0 5.4 1 1 2 4 4 4 1 Tropomyosin CENP-F_leu_zip PF10473.4 EMR69191.1 - 0.00088 19.1 24.2 0.00088 19.1 16.8 7.1 1 1 5 6 6 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EMR69191.1 - 0.0026 17.3 125.7 1 8.7 8.8 5.5 1 1 4 5 5 5 3 Intermediate filament protein Fib_alpha PF08702.5 EMR69191.1 - 0.003 17.6 81.0 0.061 13.4 6.9 7.0 2 2 6 8 8 8 4 Fibrinogen alpha/beta chain family Lebercilin PF15619.1 EMR69191.1 - 0.0035 16.8 23.7 0.0035 16.8 16.4 6.9 1 1 5 6 6 6 2 Ciliary protein causing Leber congenital amaurosis disease ERM PF00769.14 EMR69191.1 - 0.0036 16.8 31.7 0.0036 16.8 21.9 6.2 1 1 3 5 5 5 1 Ezrin/radixin/moesin family DUF3584 PF12128.3 EMR69191.1 - 0.0045 14.3 139.8 0.018 12.4 37.7 3.6 1 1 2 3 3 3 2 Protein of unknown function (DUF3584) MscS_porin PF12795.2 EMR69191.1 - 0.0046 16.3 137.3 0.42 9.9 31.5 5.2 1 1 4 5 5 5 4 Mechanosensitive ion channel porin domain Laminin_II PF06009.7 EMR69191.1 - 0.0092 15.7 14.2 0.0092 15.7 9.8 7.4 1 1 5 8 8 7 2 Laminin Domain II Reo_sigmaC PF04582.7 EMR69191.1 - 0.012 14.8 58.3 0.079 12.1 5.8 5.6 1 1 5 6 6 6 0 Reovirus sigma C capsid protein FliJ PF02050.11 EMR69191.1 - 0.016 15.2 18.8 0.016 15.2 13.0 7.5 1 1 6 8 8 8 0 Flagellar FliJ protein Tup_N PF08581.5 EMR69191.1 - 0.38 10.9 91.1 0.11 12.6 7.5 9.2 2 2 7 9 9 9 0 Tup N-terminal DUF4201 PF13870.1 EMR69191.1 - 0.48 9.8 121.8 0.45 9.9 22.3 7.6 1 1 6 7 7 7 0 Domain of unknown function (DUF4201) BicD PF09730.4 EMR69191.1 - 0.55 8.5 120.6 0.076 11.3 12.0 4.2 1 1 3 4 4 4 0 Microtubule-associated protein Bicaudal-D NPV_P10 PF05531.7 EMR69191.1 - 4.3 7.6 63.4 0.64 10.3 1.4 10.2 2 2 8 10 10 9 0 Nucleopolyhedrovirus P10 protein MtrB PF05440.7 EMR69191.1 - 9 6.4 5.8 42 4.2 0.2 3.8 2 1 1 3 3 2 0 Tetrahydromethanopterin S-methyltransferase subunit B SH3_1 PF00018.23 EMR69192.1 - 2.5e-37 126.0 7.1 2e-14 52.7 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 EMR69192.1 - 4.4e-37 125.5 0.2 8.2e-37 124.7 0.2 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 EMR69192.1 - 3.3e-35 119.4 7.5 4.6e-12 45.3 0.1 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EMR69192.1 - 1.4e-27 94.9 0.1 5.5e-09 35.3 0.0 4.3 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 EMR69192.1 - 4.4e-06 26.7 3.4 0.0061 16.7 0.6 3.5 3 0 0 3 3 3 2 Bacterial SH3 domain Mito_carr PF00153.22 EMR69193.1 - 1.3e-56 188.2 5.8 1.3e-20 72.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SpoIIAA-like PF11964.3 EMR69193.1 - 0.079 13.2 0.2 1 9.6 0.1 2.2 2 0 0 2 2 2 0 SpoIIAA-like Prefoldin PF02996.12 EMR69194.1 - 2.3e-16 59.5 0.0 3.8e-16 58.8 0.0 1.3 1 1 0 1 1 1 1 Prefoldin subunit Lactamase_B PF00753.22 EMR69194.1 - 0.014 15.0 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily CCDC155 PF14662.1 EMR69194.1 - 0.027 14.0 0.6 0.04 13.5 0.4 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Mating_N PF12731.2 EMR69194.1 - 0.071 12.9 0.2 1.3 8.9 0.1 2.0 2 0 0 2 2 2 0 Mating-type protein beta 1 Spatacsin_C PF14649.1 EMR69194.1 - 0.08 11.7 0.6 0.13 11.0 0.3 1.4 1 1 0 1 1 1 0 Spatacsin C-terminus Sec2p PF06428.6 EMR69194.1 - 0.085 12.7 1.1 0.085 12.7 0.8 1.7 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Mst1_SARAH PF11629.3 EMR69194.1 - 0.099 12.4 1.6 1.6 8.6 0.2 2.2 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 TRAM_LAG1_CLN8 PF03798.11 EMR69195.1 - 1.4e-48 165.1 14.7 2.2e-48 164.4 10.2 1.3 1 0 0 1 1 1 1 TLC domain Phage_F PF02305.12 EMR69195.1 - 0.067 11.7 0.1 0.093 11.2 0.1 1.1 1 0 0 1 1 1 0 Capsid protein (F protein) SecD_SecF PF02355.11 EMR69195.1 - 0.57 9.3 4.2 10 5.2 0.3 3.1 3 0 0 3 3 3 0 Protein export membrane protein WD40 PF00400.27 EMR69196.1 - 1.6e-55 183.0 14.7 5.5e-10 38.7 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EMR69196.1 - 0.00034 18.8 4.6 0.77 7.8 0.1 4.2 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EMR69196.1 - 0.016 14.7 0.5 6.2 6.1 0.1 2.7 2 1 0 2 2 2 0 PQQ-like domain Nucleoporin_N PF08801.6 EMR69196.1 - 0.1 11.3 0.0 12 4.5 0.0 2.9 2 1 0 3 3 3 0 Nup133 N terminal like Ank_5 PF13857.1 EMR69197.1 - 2.4e-36 122.9 9.4 2.7e-10 40.1 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR69197.1 - 1.5e-34 117.7 10.9 4.4e-08 33.4 0.2 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 EMR69197.1 - 1.5e-31 108.5 1.9 4.9e-20 71.6 0.3 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMR69197.1 - 2.9e-26 88.9 0.2 0.00029 20.7 0.0 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.25 EMR69197.1 - 4.5e-26 89.3 1.7 9.9e-06 25.1 0.1 5.4 6 0 0 6 6 6 5 Ankyrin repeat HhH-GPD PF00730.20 EMR69198.1 - 2.9e-08 33.9 0.0 6.3e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SEN1_N PF12726.2 EMR69199.1 - 4.2e-149 497.8 14.3 1.2e-115 387.3 5.3 2.1 1 1 1 2 2 2 2 SEN1 N terminal AAA_11 PF13086.1 EMR69199.1 - 3.1e-26 92.4 1.2 4.8e-26 91.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMR69199.1 - 1.4e-11 43.9 0.2 7.3e-11 41.6 0.3 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EMR69199.1 - 4.1e-07 29.7 0.2 8.7e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 EMR69199.1 - 0.0068 15.7 0.2 0.027 13.7 0.1 2.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 EMR69199.1 - 0.012 15.0 0.1 0.031 13.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EMR69199.1 - 0.079 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase GST_N_2 PF13409.1 EMR69200.1 - 0.00028 20.8 0.0 0.00069 19.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMR69200.1 - 0.0011 19.1 0.1 0.0029 17.7 0.0 1.6 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMR69200.1 - 0.01 15.9 0.0 0.032 14.4 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR69200.1 - 0.026 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ATP-synt_C PF00137.16 EMR69201.1 - 1.3e-28 98.7 27.4 4.7e-18 64.8 4.6 2.6 3 0 0 3 3 3 2 ATP synthase subunit C adh_short PF00106.20 EMR69202.1 - 4.5e-25 88.4 6.4 5.5e-25 88.2 3.6 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Abhydrolase_6 PF12697.2 EMR69202.1 - 1.8e-22 80.3 1.9 1.8e-22 80.3 1.3 2.4 2 1 1 3 3 3 1 Alpha/beta hydrolase family adh_short_C2 PF13561.1 EMR69202.1 - 9.4e-15 55.0 0.2 1.3e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR69202.1 - 3.6e-13 49.5 3.3 6.6e-13 48.7 2.3 1.4 1 0 0 1 1 1 1 KR domain Abhydrolase_5 PF12695.2 EMR69202.1 - 2.8e-05 23.9 1.6 0.00013 21.7 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family NAD_binding_10 PF13460.1 EMR69202.1 - 0.0002 21.4 0.3 0.00074 19.5 0.2 2.0 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EMR69202.1 - 0.00068 18.8 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EMR69202.1 - 0.012 14.8 0.2 0.018 14.3 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family DFP PF04127.10 EMR69202.1 - 0.062 12.9 0.7 0.12 11.9 0.5 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Ndr PF03096.9 EMR69202.1 - 0.063 11.7 0.0 0.095 11.1 0.0 1.2 1 0 0 1 1 1 0 Ndr family PfkB PF00294.19 EMR69202.1 - 0.069 12.2 0.2 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Abhydrolase_1 PF00561.15 EMR69202.1 - 0.082 12.4 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Epimerase PF01370.16 EMR69202.1 - 0.088 12.2 0.6 0.33 10.3 0.4 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family tRNA_bind PF01588.15 EMR69203.1 - 3.7e-22 77.9 0.1 3.7e-21 74.7 0.1 2.3 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EMR69203.1 - 3.6e-07 30.5 0.0 8.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMR69203.1 - 0.00011 22.1 0.0 0.00034 20.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMR69203.1 - 0.00069 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DHHA2 PF02833.9 EMR69204.1 - 3.5e-19 69.2 0.0 5.4e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EMR69204.1 - 2.3e-07 30.5 0.0 4.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 DHH family PPR_3 PF13812.1 EMR69205.1 - 9.7e-06 25.4 2.2 1.2 9.5 0.0 4.7 4 0 0 4 4 4 2 Pentatricopeptide repeat domain Oligomerisation PF02410.10 EMR69205.1 - 4e-05 23.5 0.0 0.00049 20.0 0.0 2.5 1 1 0 1 1 1 1 Oligomerisation domain PPR PF01535.15 EMR69205.1 - 0.08 12.9 0.2 12 6.0 0.0 3.7 4 0 0 4 4 4 0 PPR repeat RNA_pol PF00940.14 EMR69206.1 - 1e-163 544.5 0.0 2.2e-163 543.4 0.0 1.6 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EMR69206.1 - 3.3e-72 243.4 1.7 5.5e-72 242.7 1.2 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal adh_short PF00106.20 EMR69208.1 - 3.9e-11 43.1 0.0 1e-10 41.8 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR69208.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR69208.1 - 0.0057 16.6 0.1 0.023 14.7 0.0 2.1 2 1 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 EMR69208.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase UQ_con PF00179.21 EMR69210.1 - 9.8e-26 89.8 0.2 1.3e-25 89.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.18 EMR69211.1 - 1.4e-37 129.9 1.1 1.6e-37 129.6 0.7 1.1 1 0 0 1 1 1 1 Surface antigen peroxidase PF00141.18 EMR69212.1 - 4e-21 75.5 1.5 8.2e-21 74.5 1.0 1.5 1 0 0 1 1 1 1 Peroxidase CorA PF01544.13 EMR69213.1 - 6.1e-10 38.6 0.5 2.7e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Val_tRNA-synt_C PF10458.4 EMR69213.1 - 0.011 15.7 0.1 0.13 12.3 0.0 2.3 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm SWIB PF02201.13 EMR69213.1 - 0.061 13.0 0.0 0.96 9.1 0.0 2.3 2 0 0 2 2 2 0 SWIB/MDM2 domain AAA PF00004.24 EMR69214.1 - 3.9e-27 95.0 0.0 6.2e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EMR69214.1 - 6.5e-06 26.0 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 EMR69214.1 - 1.3e-05 24.6 0.8 3.7e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.1 EMR69214.1 - 1.4e-05 25.1 0.0 3.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 EMR69214.1 - 0.0001 21.5 0.0 0.00023 20.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EMR69214.1 - 0.00023 20.2 0.0 0.00052 19.1 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMR69214.1 - 0.00052 19.7 0.0 0.0016 18.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EMR69214.1 - 0.00059 19.3 0.0 0.00092 18.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.8 EMR69214.1 - 0.00093 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 EMR69214.1 - 0.0021 18.2 0.0 0.51 10.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EMR69214.1 - 0.0038 18.0 0.0 0.014 16.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EMR69214.1 - 0.006 16.0 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain ResIII PF04851.10 EMR69214.1 - 0.0079 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 EMR69214.1 - 0.0091 15.7 0.0 0.036 13.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EMR69214.1 - 0.013 14.2 0.0 0.026 13.2 0.0 1.6 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 EMR69214.1 - 0.028 14.3 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EMR69214.1 - 0.035 14.4 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EMR69214.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_2 PF07724.9 EMR69214.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) KaiC PF06745.8 EMR69214.1 - 0.13 11.3 0.1 0.9 8.6 0.0 2.0 1 1 1 2 2 2 0 KaiC She9_MDM33 PF05546.6 EMR69215.1 - 1.8e-80 269.3 3.4 2.5e-80 268.9 2.3 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family Uds1 PF15456.1 EMR69215.1 - 0.0034 17.3 1.4 0.0034 17.3 1.0 1.8 2 0 0 2 2 2 1 Up-regulated During Septation PsbH PF00737.15 EMR69215.1 - 0.027 14.0 0.6 0.046 13.2 0.4 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein CENP-F_leu_zip PF10473.4 EMR69215.1 - 0.038 13.8 2.0 0.94 9.3 0.0 2.6 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Peptidase_C28 PF05408.6 EMR69215.1 - 0.049 13.1 0.0 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 Foot-and-mouth virus L-proteinase Med4 PF10018.4 EMR69215.1 - 0.063 12.6 0.3 0.063 12.6 0.2 2.7 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF2664 PF10867.3 EMR69215.1 - 0.69 10.5 3.8 20 5.8 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2664) DUF904 PF06005.7 EMR69215.1 - 1.5 9.1 3.8 9.1 6.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF904) GST_C_3 PF14497.1 EMR69216.1 - 8.7e-06 26.1 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 EMR69216.1 - 0.00012 22.3 0.0 0.00036 20.7 0.0 1.8 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 EMR69216.1 - 0.00017 21.4 0.1 0.00038 20.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2731 PF10806.3 EMR69216.1 - 0.036 14.3 0.1 0.2 11.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2731) RGS PF00615.14 EMR69217.1 - 3.6e-10 39.9 0.0 7.6e-09 35.6 0.0 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain Pro-kuma_activ PF09286.6 EMR69218.1 - 1.4e-38 132.1 0.1 3.2e-38 131.0 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EMR69218.1 - 2.7e-11 43.1 1.2 4.8e-11 42.3 0.8 1.4 1 0 0 1 1 1 1 Subtilase family DAO PF01266.19 EMR69221.1 - 5e-30 104.6 6.5 6.1e-30 104.3 4.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR69221.1 - 1.8e-05 24.6 0.2 0.00019 21.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMR69221.1 - 0.00053 18.9 0.0 0.00081 18.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EMR69221.1 - 0.0015 17.6 0.0 0.0037 16.3 0.0 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EMR69221.1 - 0.0062 16.9 0.1 0.036 14.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR69221.1 - 0.017 14.9 0.5 1.4 8.7 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMR69221.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR69221.1 - 0.14 10.6 0.1 0.4 9.1 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 EMR69221.1 - 0.15 10.7 0.1 0.37 9.3 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase CP12 PF02672.10 EMR69222.1 - 0.00011 22.5 0.1 0.00024 21.5 0.1 1.5 1 0 0 1 1 1 1 CP12 domain GvpL_GvpF PF06386.6 EMR69222.1 - 0.011 15.3 0.5 0.015 14.9 0.3 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF NPV_P10 PF05531.7 EMR69222.1 - 0.052 13.7 0.5 29 4.9 0.2 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 EMR69222.1 - 0.066 12.3 0.6 0.71 9.0 0.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sedlin_N PF04628.8 EMR69223.1 - 6.6e-20 71.3 0.0 8.4e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region MFS_1 PF07690.11 EMR69224.1 - 1.5e-32 112.7 31.6 1.5e-32 112.7 21.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR69224.1 - 1.5e-06 26.7 3.6 1.5e-06 26.7 2.5 2.3 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) eIF-1a PF01176.14 EMR69225.1 - 3.9e-17 61.4 0.0 5.3e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 FAD_binding_4 PF01565.18 EMR69226.1 - 7.6e-24 83.7 1.6 6.9e-23 80.6 1.2 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EMR69226.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like HAD PF12710.2 EMR69227.1 - 3.3e-15 56.7 0.0 4.3e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMR69227.1 - 0.00033 20.9 0.0 0.00088 19.5 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EMR69227.1 - 0.0034 16.5 0.0 0.1 11.7 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase UMPH-1 PF05822.7 EMR69227.1 - 0.017 14.4 0.0 0.039 13.2 0.0 1.7 1 1 1 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 EMR69227.1 - 0.02 15.2 0.1 0.27 11.5 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Isochorismatase PF00857.15 EMR69228.1 - 8.4e-38 130.0 0.0 9.7e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family OTU PF02338.14 EMR69229.1 - 6.9e-18 65.3 0.1 3.7e-14 53.3 0.0 3.1 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EMR69229.1 - 1.5e-06 27.7 0.0 0.0029 16.9 0.0 2.7 2 1 0 3 3 3 2 Peptidase C65 Otubain Chitin_synth_1 PF01644.12 EMR69230.1 - 3.6e-70 234.9 0.0 5.5e-70 234.3 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EMR69230.1 - 7e-27 92.9 0.0 1.4e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EMR69230.1 - 1.4e-25 89.7 0.0 1.7e-21 76.2 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EMR69230.1 - 4e-11 42.9 0.1 4e-11 42.9 0.1 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMR69230.1 - 8.4e-08 32.2 0.0 2.1e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 ORC4_C PF14629.1 EMR69232.1 - 8.1e-54 182.0 0.0 9.2e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus CD20 PF04103.10 EMR69234.1 - 0.014 15.2 0.9 0.014 15.2 0.6 1.9 2 0 0 2 2 2 0 CD20-like family Phage_DNA_bind PF02303.12 EMR69236.1 - 0.018 15.0 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Helix-destabilising protein Syndecan PF01034.15 EMR69237.1 - 2.3e-05 23.9 0.0 4.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain P12 PF12669.2 EMR69237.1 - 7.2 6.8 6.1 0.4 10.9 0.5 1.6 2 0 0 2 2 2 0 Virus attachment protein p12 family Ribosomal_S25 PF03297.10 EMR69238.1 - 0.76 9.8 3.8 1.1 9.3 2.6 1.4 1 1 0 1 1 1 0 S25 ribosomal protein MFS_1 PF07690.11 EMR69239.1 - 1.3e-23 83.2 39.8 1.8e-16 59.7 8.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FYVE PF01363.16 EMR69240.1 - 0.007 16.2 19.7 0.18 11.6 0.9 2.3 2 0 0 2 2 2 2 FYVE zinc finger FYVE_2 PF02318.11 EMR69240.1 - 0.012 15.5 11.4 0.26 11.1 0.2 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger F-box-like PF12937.2 EMR69242.1 - 3.4e-06 26.6 1.6 4.8e-06 26.2 0.3 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMR69242.1 - 0.037 13.6 0.4 0.037 13.6 0.3 2.1 2 0 0 2 2 2 0 F-box domain DUF3638 PF12340.3 EMR69244.1 - 2.6e-68 229.4 0.1 1e-41 142.3 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EMR69244.1 - 4.5e-17 60.8 0.2 8.9e-17 59.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) PKD_channel PF08016.7 EMR69244.1 - 0.14 10.5 0.2 0.26 9.6 0.1 1.3 1 0 0 1 1 1 0 Polycystin cation channel Pkinase PF00069.20 EMR69247.1 - 3.6e-63 213.1 0.0 6e-63 212.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR69247.1 - 3.4e-36 124.6 0.0 5.3e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EMR69247.1 - 4.9e-30 103.0 20.2 9.7e-17 60.4 4.6 2.4 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.19 EMR69247.1 - 2.3e-14 53.6 2.5 7.5e-14 51.9 1.8 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMR69247.1 - 0.018 13.9 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 EMR69248.1 - 5.3e-15 55.2 0.0 1e-14 54.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EMR69248.1 - 0.0023 17.7 0.6 0.007 16.1 0.4 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EMR69248.1 - 0.0036 16.4 0.0 0.0062 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH_6_hur PF04655.9 EMR69248.1 - 0.0072 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase MFS_1 PF07690.11 EMR69249.1 - 3.6e-43 147.6 30.0 3.6e-43 147.6 20.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EMR69249.1 - 0.0011 17.1 3.9 0.009 14.1 0.6 2.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Aldedh PF00171.17 EMR69250.1 - 1.7e-18 66.2 4.5 4.1e-11 41.9 2.1 2.6 1 1 1 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.12 EMR69250.1 - 0.0029 16.5 0.0 0.0057 15.6 0.0 1.4 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) eIF-5_eIF-2B PF01873.12 EMR69251.1 - 1.3e-44 150.8 0.5 2.5e-44 149.9 0.3 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Ykof PF07615.6 EMR69251.1 - 0.076 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 YKOF-related Family MYT1 PF08474.6 EMR69251.1 - 0.25 10.7 3.8 6.6 6.1 0.1 2.5 1 1 1 2 2 2 0 Myelin transcription factor 1 ALG3 PF05208.8 EMR69253.1 - 1.8e-136 455.2 17.1 2.2e-136 454.9 11.9 1.0 1 0 0 1 1 1 1 ALG3 protein Thioredoxin PF00085.15 EMR69254.1 - 5.4e-25 87.0 0.0 7.8e-25 86.5 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EMR69254.1 - 1.9e-08 34.3 0.1 1.1e-07 31.8 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EMR69254.1 - 4.1e-07 29.9 0.0 6.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EMR69254.1 - 4.4e-06 26.8 0.1 3.6e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EMR69254.1 - 4.5e-06 26.2 0.1 8.1e-06 25.4 0.0 1.3 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EMR69254.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family HyaE PF07449.6 EMR69254.1 - 0.00063 19.6 0.0 0.00097 19.0 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 EMR69254.1 - 0.00082 18.9 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_5 PF13743.1 EMR69254.1 - 0.12 11.9 0.0 1.7 8.1 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.1 EMR69254.1 - 0.16 11.4 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF2347 PF09804.4 EMR69255.1 - 3.4e-72 243.0 0.0 1.3e-48 165.7 0.0 2.2 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EMR69255.1 - 2.7e-47 161.1 0.0 5.6e-47 160.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Med3 PF11593.3 EMR69255.1 - 0.3 10.3 6.2 0.47 9.6 4.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ank_2 PF12796.2 EMR69256.1 - 4.3e-60 200.0 6.5 5.5e-16 58.6 0.0 6.2 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 EMR69256.1 - 1.1e-55 182.7 15.5 3.4e-07 29.7 0.0 10.5 10 1 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 EMR69256.1 - 2.1e-47 158.6 5.4 4.2e-10 39.8 0.0 7.3 5 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR69256.1 - 6.7e-46 149.6 8.1 5.2e-05 23.1 0.0 10.2 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.1 EMR69256.1 - 6.8e-44 146.9 9.5 1e-08 35.1 0.0 8.8 3 1 7 10 10 10 9 Ankyrin repeats (many copies) DUF1843 PF08898.5 EMR69256.1 - 0.0064 16.5 0.0 10 6.2 0.1 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1843) SPRY PF00622.23 EMR69256.1 - 0.017 15.2 0.8 0.03 14.3 0.5 1.4 1 0 0 1 1 1 0 SPRY domain DUF1264 PF06884.6 EMR69257.1 - 7.3e-71 237.0 0.0 1.2e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) HET PF06985.6 EMR69257.1 - 1.3e-20 73.9 0.1 2.5e-20 73.0 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) KaiC PF06745.8 EMR69257.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 KaiC Sec63 PF02889.11 EMR69258.1 - 2.6e-47 161.6 0.0 1.8e-44 152.2 0.0 2.1 2 0 0 2 2 2 2 Sec63 Brl domain KR PF08659.5 EMR69258.1 - 6.8e-23 81.2 0.1 1.4e-22 80.2 0.1 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR69258.1 - 1.2e-17 64.3 0.1 2.3e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase DnaJ PF00226.26 EMR69258.1 - 1e-16 60.3 0.2 2.3e-16 59.2 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain PP-binding PF00550.20 EMR69258.1 - 4.7e-11 42.7 0.0 1.2e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Sugar_tr PF00083.19 EMR69259.1 - 2e-10 39.8 2.7 2.2e-10 39.7 1.5 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter CoA_transf_3 PF02515.12 EMR69260.1 - 0.00059 19.1 0.0 0.00077 18.7 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III p450 PF00067.17 EMR69261.1 - 2e-35 122.2 0.0 5.4e-35 120.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Tetraspannin PF00335.15 EMR69262.1 - 6.9 5.8 8.3 2.2 7.5 0.6 2.4 2 0 0 2 2 2 0 Tetraspanin family DUF1275 PF06912.6 EMR69263.1 - 1e-38 132.6 14.2 1.3e-38 132.3 9.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PGG PF13962.1 EMR69263.1 - 0.016 14.8 0.8 0.041 13.4 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function OB_NTP_bind PF07717.11 EMR69264.1 - 1.3e-11 44.3 0.0 2.4e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMR69264.1 - 3.1e-11 43.1 0.0 8.1e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 Helicase associated domain (HA2) Thymidylate_kin PF02223.12 EMR69264.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase VirE PF05272.6 EMR69264.1 - 0.057 12.8 0.0 2 7.8 0.0 2.5 2 1 0 2 2 2 0 Virulence-associated protein E DUF3760 PF12586.3 EMR69264.1 - 0.1 12.4 0.1 0.58 10.0 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3760) Bac_luciferase PF00296.15 EMR69265.1 - 1.4e-50 172.1 0.0 2.1e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase COesterase PF00135.23 EMR69266.1 - 5.5e-46 157.3 0.0 5.5e-31 107.8 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR69266.1 - 0.0029 17.2 0.1 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold SnoaL_2 PF12680.2 EMR69267.1 - 0.1 13.0 0.2 0.19 12.1 0.2 1.6 1 1 0 1 1 1 0 SnoaL-like domain F_bP_aldolase PF01116.15 EMR69269.1 - 2.8e-83 279.3 0.0 3.4e-57 193.7 0.0 2.1 2 0 0 2 2 2 2 Fructose-bisphosphate aldolase class-II DUF3573 PF12097.3 EMR69269.1 - 0.2 10.2 0.6 0.32 9.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) NYD-SP28_assoc PF14775.1 EMR69269.1 - 9.4 6.0 9.0 0.58 9.8 0.1 3.0 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF3632 PF12311.3 EMR69271.1 - 2.1e-28 99.3 0.1 1.2e-26 93.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3632) DUF221 PF02714.10 EMR69272.1 - 5.9e-97 324.4 17.0 5.9e-97 324.4 11.8 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMR69272.1 - 5.9e-31 107.1 0.0 1.9e-30 105.4 0.0 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EMR69272.1 - 0.00077 19.9 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF4291 PF14124.1 EMR69273.1 - 5.5e-55 185.7 0.0 1.1e-54 184.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) MFS_1 PF07690.11 EMR69273.1 - 3.2e-06 26.1 13.6 0.0025 16.6 0.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF917 PF06032.7 EMR69274.1 - 5.9e-48 163.2 0.0 5.9e-34 117.1 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF917) Acyl_transf_1 PF00698.16 EMR69275.1 - 7.9e-56 189.7 0.1 5.1e-54 183.7 0.0 2.6 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 EMR69275.1 - 1.1e-51 175.0 0.6 4.2e-51 173.1 0.2 2.3 2 0 0 2 2 1 1 KR domain ketoacyl-synt PF00109.21 EMR69275.1 - 2.3e-50 171.4 2.7 1.2e-49 169.0 0.5 2.6 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 EMR69275.1 - 2.4e-38 131.6 0.6 1.7e-37 128.8 0.1 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMR69275.1 - 4.7e-35 119.9 1.5 7.2e-35 119.4 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EMR69275.1 - 8.4e-26 90.8 0.5 3.2e-25 88.8 0.0 2.1 2 0 0 2 2 2 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 EMR69275.1 - 2.1e-17 62.8 0.9 8.3e-17 60.9 0.1 2.5 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMR69275.1 - 1.2e-16 61.0 0.0 3.5e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR69275.1 - 8.5e-14 51.5 0.0 3.3e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EMR69275.1 - 1.5e-10 42.0 0.0 6.6e-09 36.7 0.0 3.7 4 0 0 4 4 3 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EMR69275.1 - 8.8e-10 38.3 0.0 2.4e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR69275.1 - 3.6e-09 36.9 0.0 9.1e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR69275.1 - 5.1e-08 33.0 0.0 1.6e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EMR69275.1 - 1.1e-07 32.4 0.0 8.4e-07 29.5 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 EMR69275.1 - 4.4e-05 23.1 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 EMR69275.1 - 0.0003 19.9 0.0 0.0011 18.1 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EMR69275.1 - 0.00077 18.9 0.0 0.002 17.5 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Thiolase_N PF00108.18 EMR69275.1 - 0.002 17.1 0.0 0.0041 16.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 EMR69275.1 - 0.004 17.1 0.0 0.013 15.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III PF08545.5 EMR69275.1 - 0.0042 16.7 0.3 0.012 15.2 0.2 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF3606 PF12244.3 EMR69275.1 - 0.082 12.5 0.0 0.28 10.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Macoilin PF09726.4 EMR69276.1 - 0.021 13.1 5.9 0.026 12.8 4.1 1.2 1 0 0 1 1 1 0 Transmembrane protein SAPS PF04499.10 EMR69276.1 - 1.9 6.9 5.3 2.6 6.5 3.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paramyxo_ncap PF00973.14 EMR69276.1 - 2.8 6.5 7.8 3.8 6.0 5.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SnoaL_4 PF13577.1 EMR69277.1 - 4.1e-14 52.5 0.5 4.9e-14 52.3 0.3 1.0 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EMR69277.1 - 0.00025 21.1 0.4 0.00033 20.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Fic PF02661.13 EMR69279.1 - 1.4e-12 48.1 0.0 2.8e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family MogR_DNAbind PF12181.3 EMR69280.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) Peroxidase_2 PF01328.12 EMR69281.1 - 3.9e-05 22.4 0.1 4.5e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 MFS_1 PF07690.11 EMR69282.1 - 1.3e-10 40.5 26.3 1.2e-07 30.7 7.1 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Glyco_hydro_10 PF00331.15 EMR69283.1 - 2.7e-16 59.5 0.0 3.2e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Saf-Nte_pilin PF09460.5 EMR69283.1 - 0.096 12.4 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Saf-pilin pilus formation protein GHL6 PF14871.1 EMR69284.1 - 8e-23 80.9 0.0 1.5e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 DUF187 PF02638.10 EMR69284.1 - 3.6e-08 32.6 0.0 5.6e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 Glyco_hydro_42M PF08532.5 EMR69284.1 - 8.5e-06 25.0 0.0 2.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Glyco_hydro_42 PF02449.10 EMR69284.1 - 0.00018 20.7 0.0 0.00027 20.2 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_66 PF13199.1 EMR69284.1 - 0.13 10.6 0.1 2.7 6.3 0.0 2.6 3 0 0 3 3 3 0 Glycosyl hydrolase family 66 MARVEL PF01284.18 EMR69286.1 - 1.8e-10 40.8 20.2 2.4e-10 40.4 11.9 2.1 1 1 1 2 2 2 1 Membrane-associating domain DUF588 PF04535.7 EMR69286.1 - 0.02 14.4 2.2 0.02 14.4 1.5 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF588) adh_short PF00106.20 EMR69287.1 - 2.1e-14 53.7 0.7 2.4e-14 53.5 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR69287.1 - 2.6e-07 30.6 0.0 3e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR69287.1 - 1.1e-05 25.1 0.5 1.3e-05 24.9 0.4 1.1 1 0 0 1 1 1 1 KR domain ApbA PF02558.11 EMR69287.1 - 0.054 12.9 0.0 0.063 12.7 0.0 1.4 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EMR69287.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Helicase_RecD PF05127.9 EMR69287.1 - 0.088 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Helicase UAA PF08449.6 EMR69288.1 - 6.8e-10 38.3 19.7 8.8e-10 37.9 13.6 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EMR69288.1 - 7.9e-09 35.3 6.3 7.9e-09 35.3 4.4 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EMR69288.1 - 0.0011 18.9 5.6 0.0011 18.9 3.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF1077 PF06417.7 EMR69288.1 - 0.069 12.4 5.5 0.28 10.5 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1077) VCBS PF13517.1 EMR69289.1 - 5e-23 81.2 61.9 1.6e-09 37.9 2.1 9.6 6 2 4 10 10 10 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EMR69289.1 - 6.8e-06 25.6 47.7 0.012 15.3 1.1 8.8 8 0 0 8 8 8 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 EMR69289.1 - 0.0011 18.3 12.8 0.79 9.1 0.1 5.7 6 0 0 6 6 6 3 Insecticide toxin TcdB middle/N-terminal region MFS_1 PF07690.11 EMR69290.1 - 1e-31 109.9 28.2 7.5e-26 90.6 3.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR69290.1 - 5.6e-10 38.3 6.5 5.6e-10 38.3 4.5 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter ThiS PF02597.15 EMR69291.1 - 2.7e-09 37.3 0.0 4.1e-09 36.7 0.0 1.3 1 1 0 1 1 1 1 ThiS family AAA PF00004.24 EMR69292.1 - 2.4e-40 137.7 0.0 4.2e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR69292.1 - 4.6e-06 26.8 0.0 0.00061 19.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EMR69292.1 - 2.8e-05 23.8 0.1 0.00028 20.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMR69292.1 - 0.00035 20.5 0.0 0.0017 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EMR69292.1 - 0.0004 20.3 0.0 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EMR69292.1 - 0.0019 17.2 0.0 0.0033 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EMR69292.1 - 0.0043 17.8 0.1 0.014 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMR69292.1 - 0.0089 15.7 0.1 0.021 14.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EMR69292.1 - 0.0097 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EMR69292.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EMR69292.1 - 0.018 15.0 0.1 0.045 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMR69292.1 - 0.028 14.0 0.1 0.61 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EMR69292.1 - 0.034 14.3 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 EMR69292.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EMR69292.1 - 0.049 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EMR69292.1 - 0.074 12.1 0.1 5.9 5.9 0.0 2.5 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.7 EMR69292.1 - 0.076 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EMR69292.1 - 0.081 12.9 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EMR69292.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein SNase PF00565.12 EMR69293.1 - 4e-23 81.7 0.0 4.8e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue EAP30 PF04157.11 EMR69294.1 - 0.08 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family LRR_4 PF12799.2 EMR69294.1 - 0.17 11.5 1.9 19 5.0 0.0 3.7 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) PP2C PF00481.16 EMR69295.1 - 2.8e-54 184.2 0.0 5.8e-54 183.1 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EMR69295.1 - 2.9e-48 160.8 53.9 6.3e-08 32.0 1.8 12.3 9 3 3 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMR69295.1 - 5.9e-39 131.6 57.5 1.2e-08 34.5 0.8 9.4 5 3 5 11 11 11 10 Leucine rich repeat Guanylate_cyc PF00211.15 EMR69295.1 - 1e-28 99.9 0.0 3.1e-28 98.3 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EMR69295.1 - 4.5e-25 83.8 55.5 0.19 11.8 0.0 19.7 19 1 0 19 19 19 8 Leucine Rich Repeat LRR_7 PF13504.1 EMR69295.1 - 2.8e-16 56.7 46.9 0.43 10.9 0.1 17.1 18 0 0 18 18 18 7 Leucine rich repeat RA PF00788.18 EMR69295.1 - 2.4e-10 40.7 0.0 7.3e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 EMR69295.1 - 2.1e-06 27.1 44.1 4.2 7.7 0.1 15.4 16 1 1 17 17 17 3 Leucine Rich repeat Ad_cyc_g-alpha PF08509.6 EMR69295.1 - 4.6e-05 22.6 0.4 0.00012 21.3 0.3 1.7 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain RTC4 PF14474.1 EMR69297.1 - 3.6e-34 117.3 0.0 4.6e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 RTC4-like domain Cul7 PF11515.3 EMR69297.1 - 0.043 13.7 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Mouse development and cellular proliferation protein Cullin-7 ANTAR PF03861.9 EMR69297.1 - 0.081 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 ANTAR domain Mob1_phocein PF03637.12 EMR69298.1 - 6.6e-24 84.5 0.5 2.3e-16 59.9 0.2 2.1 2 0 0 2 2 2 2 Mob1/phocein family Methyltransf_26 PF13659.1 EMR69300.1 - 2.8e-15 56.3 0.2 4.4e-15 55.7 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain F-box-like_2 PF13013.1 EMR69301.1 - 0.029 14.0 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 F-box-like domain Prenylcys_lyase PF07156.9 EMR69302.1 - 1e-06 27.9 0.0 0.028 13.3 0.0 2.1 2 0 0 2 2 2 2 Prenylcysteine lyase DUF3336 PF11815.3 EMR69303.1 - 1.5e-34 118.5 0.1 7e-34 116.4 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EMR69303.1 - 1.8e-13 50.8 1.7 3.1e-13 50.1 0.4 2.0 2 1 0 2 2 2 1 Patatin-like phospholipase Surf_Ag_VNR PF07244.10 EMR69303.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat LSM PF01423.17 EMR69304.1 - 5e-16 58.0 0.0 6.9e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EMR69304.1 - 0.00023 21.0 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2763 PF10961.3 EMR69304.1 - 0.41 11.0 6.5 0.66 10.4 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) API5 PF05918.6 EMR69304.1 - 4.5 5.6 12.0 6.1 5.2 8.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ribosomal_S28e PF01200.13 EMR69305.1 - 7.3e-34 115.3 3.1 7.9e-34 115.2 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Dynamitin PF04912.9 EMR69306.1 - 8.6e-35 120.2 9.6 4.7e-33 114.5 6.7 2.7 1 1 0 1 1 1 1 Dynamitin FH2 PF02181.18 EMR69306.1 - 0.00063 18.7 1.6 0.54 9.0 0.0 3.0 3 0 0 3 3 3 2 Formin Homology 2 Domain Laminin_II PF06009.7 EMR69306.1 - 0.0038 16.9 13.3 0.021 14.5 0.1 4.1 4 1 1 5 5 4 2 Laminin Domain II BLOC1_2 PF10046.4 EMR69306.1 - 0.008 16.2 3.8 2.5 8.2 0.0 3.8 3 1 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1192 PF06698.6 EMR69306.1 - 0.04 13.7 12.0 0.68 9.7 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF3450 PF11932.3 EMR69306.1 - 0.049 12.9 13.6 0.083 12.1 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) IncA PF04156.9 EMR69306.1 - 0.059 12.9 8.0 2.2 7.8 0.0 3.2 3 0 0 3 3 3 0 IncA protein Bacillus_HBL PF05791.6 EMR69306.1 - 0.059 12.7 7.0 8.6 5.6 0.1 3.2 2 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Sipho_Gp157 PF05565.6 EMR69306.1 - 0.069 12.7 0.1 0.069 12.7 0.1 3.2 4 0 0 4 4 3 0 Siphovirus Gp157 BicD PF09730.4 EMR69306.1 - 0.07 11.4 10.1 0.014 13.7 0.4 2.5 2 1 1 3 3 3 0 Microtubule-associated protein Bicaudal-D Phage_GP20 PF06810.6 EMR69306.1 - 0.11 11.8 11.0 0.021 14.2 1.4 3.2 3 1 1 4 4 4 0 Phage minor structural protein GP20 Seryl_tRNA_N PF02403.17 EMR69306.1 - 0.18 11.8 10.6 3 7.9 0.1 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Snapin_Pallidin PF14712.1 EMR69306.1 - 0.19 12.0 5.6 6.8 7.0 0.1 3.7 3 1 0 3 3 3 0 Snapin/Pallidin DUF2205 PF10224.4 EMR69306.1 - 0.39 10.3 4.3 1.2 8.7 0.1 2.7 3 0 0 3 3 2 0 Predicted coiled-coil protein (DUF2205) ADIP PF11559.3 EMR69306.1 - 0.45 10.3 9.2 0.67 9.8 0.3 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding BRE1 PF08647.6 EMR69306.1 - 0.7 9.9 4.5 3.8 7.5 0.1 3.1 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF4446 PF14584.1 EMR69306.1 - 0.73 9.6 4.1 10 5.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) TPR_MLP1_2 PF07926.7 EMR69306.1 - 0.84 9.3 14.5 5.5 6.7 0.5 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.15 EMR69306.1 - 1.3 8.8 9.7 4.4 7.1 0.1 3.7 3 0 0 3 3 3 0 Prefoldin subunit CENP-F_leu_zip PF10473.4 EMR69306.1 - 1.4 8.7 13.7 1.9 8.3 0.8 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GrpE PF01025.14 EMR69306.1 - 1.7 8.1 7.9 0.68 9.4 0.4 3.1 2 1 1 3 3 3 0 GrpE DUF4600 PF15372.1 EMR69306.1 - 3 8.0 9.0 1.7 8.8 0.2 3.9 3 2 2 5 5 5 0 Domain of unknown function (DUF4600) Herpes_UL25 PF01499.11 EMR69306.1 - 4.3 5.5 10.8 0.35 9.1 1.0 2.8 3 0 0 3 3 3 0 Herpesvirus UL25 family Vps51 PF08700.6 EMR69306.1 - 4.4 7.2 7.0 19 5.2 0.0 3.7 4 0 0 4 4 4 0 Vps51/Vps67 HSCB_C PF07743.8 EMR69306.1 - 7.2 7.1 10.4 6.3 7.3 0.0 3.9 3 1 1 4 4 4 0 HSCB C-terminal oligomerisation domain DivIC PF04977.10 EMR69306.1 - 7.6 6.0 14.4 2.4 7.6 0.1 4.0 4 1 1 5 5 4 0 Septum formation initiator Cpn60_TCP1 PF00118.19 EMR69307.1 - 3.2e-135 451.5 11.4 4e-135 451.1 7.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 EMR69307.1 - 0.0084 15.5 0.0 0.029 13.8 0.0 1.9 1 0 0 1 1 1 1 Phage Tail Protein X DUF500 PF04366.7 EMR69308.1 - 2.4e-30 104.5 0.0 4.7e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) DUF1512 PF07431.7 EMR69308.1 - 0.11 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) Actin PF00022.14 EMR69309.1 - 1.7e-08 33.2 0.0 1.2e-07 30.4 0.0 2.4 2 1 0 2 2 2 1 Actin Leo1 PF04004.8 EMR69310.1 - 1.1e-27 96.8 0.5 1.1e-27 96.8 0.3 1.7 2 0 0 2 2 2 1 Leo1-like protein Rax2 PF12768.2 EMR69311.1 - 1.5e-92 309.7 11.5 8.2e-84 281.1 0.1 4.7 4 1 1 5 5 5 4 Cortical protein marker for cell polarity Kelch_1 PF01344.20 EMR69311.1 - 0.00076 18.9 0.5 0.028 13.9 0.0 3.5 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 EMR69311.1 - 0.033 13.9 0.2 0.033 13.9 0.2 4.0 4 0 0 4 4 4 0 Galactose oxidase, central domain tRNA-synt_2 PF00152.15 EMR69312.1 - 4.9e-88 295.1 0.4 4.9e-88 295.1 0.3 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMR69312.1 - 2.8e-10 39.9 0.0 6.2e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EMR69312.1 - 1.7e-07 30.7 0.0 0.00033 19.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Peptidase_S49_N PF08496.5 EMR69312.1 - 1.8 8.3 6.9 4 7.2 4.8 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pkr1 PF08636.5 EMR69313.1 - 1.4e-34 117.9 6.6 1.8e-34 117.6 4.6 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FHIPEP PF00771.15 EMR69313.1 - 0.0032 15.8 0.0 0.0037 15.6 0.0 1.0 1 0 0 1 1 1 1 FHIPEP family OAD_gamma PF04277.8 EMR69313.1 - 0.026 14.9 0.7 0.052 13.9 0.5 1.7 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain CobD_Cbib PF03186.8 EMR69313.1 - 0.051 12.6 0.1 0.061 12.3 0.1 1.1 1 0 0 1 1 1 0 CobD/Cbib protein RCC1 PF00415.13 EMR69314.1 - 4.7e-38 129.1 8.0 2.1e-08 34.2 0.0 7.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMR69314.1 - 4.5e-22 77.0 13.1 3.3e-06 26.5 0.1 5.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat SIS_2 PF13580.1 EMR69314.1 - 0.057 13.1 0.0 0.52 10.0 0.0 2.2 2 0 0 2 2 2 0 SIS domain CBM_X PF06204.6 EMR69314.1 - 0.085 12.3 0.5 1.4 8.4 0.0 2.9 3 0 0 3 3 3 0 Putative carbohydrate binding domain PLRV_ORF5 PF01690.12 EMR69314.1 - 0.48 9.5 9.8 0.72 8.9 6.8 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Bd3614_N PF14442.1 EMR69314.1 - 0.95 9.4 6.8 2.2 8.2 4.7 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal ketoacyl-synt PF00109.21 EMR69315.1 - 1.2e-19 70.7 0.1 2.9e-19 69.5 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 EMR69315.1 - 9e-17 60.9 0.1 2.4e-16 59.6 0.1 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EMR69315.1 - 7.2e-12 45.2 0.0 1.8e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EMR69315.1 - 9.4e-05 22.3 0.0 0.00027 20.8 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR69315.1 - 0.0033 17.1 0.0 0.011 15.4 0.0 1.9 1 0 0 1 1 1 1 KR domain RicinB_lectin_2 PF14200.1 EMR69316.1 - 7.3e-05 23.0 0.0 0.00015 22.1 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like PA14 PF07691.7 EMR69316.1 - 0.029 13.9 0.3 0.035 13.7 0.2 1.2 1 0 0 1 1 1 0 PA14 domain Acyl_transf_1 PF00698.16 EMR69317.1 - 3e-81 273.2 0.0 1.7e-78 264.1 0.0 3.4 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EMR69317.1 - 3.5e-39 132.9 0.0 6.7e-39 132.0 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EMR69317.1 - 4.1e-30 103.3 0.1 1.1e-29 101.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EMR69317.1 - 3.1e-21 75.5 0.0 1.5e-20 73.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EMR69317.1 - 0.00024 20.3 1.2 0.011 14.9 0.6 2.8 2 1 0 2 2 2 1 Nitronate monooxygenase PCIF1_WW PF12237.3 EMR69317.1 - 0.11 11.8 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain PAPA-1 PF04795.7 EMR69318.1 - 0.81 10.4 9.9 0.16 12.6 2.4 2.1 2 0 0 2 2 2 0 PAPA-1-like conserved region HAD_2 PF13419.1 EMR69319.1 - 3.6e-27 95.7 0.0 4.3e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Zn_clus PF00172.13 EMR69321.1 - 3.3e-09 36.4 7.9 3.3e-09 36.4 5.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMR69321.1 - 0.00024 20.0 0.0 0.00043 19.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ACBP PF00887.14 EMR69322.1 - 2.1e-26 91.4 0.9 2.3e-26 91.2 0.6 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein WD40 PF00400.27 EMR69323.1 - 2e-19 68.6 1.3 0.00018 21.2 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF3431 PF11913.3 EMR69324.1 - 4.5e-87 291.1 0.0 5.6e-87 290.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) BCIP PF13862.1 EMR69325.1 - 2.1e-65 219.9 0.0 2.5e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein WD40 PF00400.27 EMR69326.1 - 6.7e-39 130.4 14.8 4.8e-10 38.9 0.2 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EMR69326.1 - 3.7e-06 25.3 9.7 0.059 11.4 0.1 4.7 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Suppressor_APC PF11414.3 EMR69326.1 - 0.068 12.9 0.4 0.28 10.9 0.2 2.0 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Seryl_tRNA_N PF02403.17 EMR69326.1 - 0.083 12.9 1.4 0.24 11.4 1.0 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PQQ_2 PF13360.1 EMR69326.1 - 0.084 12.3 1.4 0.46 9.9 0.2 2.5 2 1 0 2 2 2 0 PQQ-like domain HAUS-augmin3 PF14932.1 EMR69326.1 - 0.096 11.8 1.8 0.15 11.2 1.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 APG6 PF04111.7 EMR69326.1 - 0.16 10.9 0.6 0.23 10.4 0.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-C3HC4_3 PF13920.1 EMR69327.1 - 1.4e-07 31.0 3.3 1.4e-07 31.0 2.3 2.9 2 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMR69327.1 - 1.7e-07 30.9 8.3 1.7e-07 30.9 5.7 2.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMR69327.1 - 2.3e-07 30.7 2.9 2.3e-07 30.7 2.0 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR69327.1 - 2.1e-06 27.3 7.2 2.1e-06 27.3 5.0 2.9 2 1 2 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMR69327.1 - 0.00017 21.1 7.6 0.00017 21.1 5.2 2.9 3 1 1 4 4 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMR69327.1 - 0.0017 18.0 2.6 0.0017 18.0 1.8 2.7 2 1 1 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EMR69327.1 - 0.0022 17.4 4.0 0.007 15.8 2.7 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 EMR69327.1 - 0.0041 17.2 15.7 0.0041 17.1 8.9 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EMR69327.1 - 0.0055 16.5 3.6 0.0055 16.5 2.5 2.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING DUF2390 PF09523.5 EMR69327.1 - 0.083 13.0 0.9 0.14 12.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) zf-Apc11 PF12861.2 EMR69327.1 - 2 8.3 8.3 0.69 9.7 0.9 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Tyr-DNA_phospho PF06087.7 EMR69328.1 - 4.3e-108 361.8 0.0 9.1e-108 360.7 0.0 1.5 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EMR69328.1 - 0.076 12.7 0.1 1.7 8.4 0.0 2.4 2 1 0 2 2 2 0 PLD-like domain SR-25 PF10500.4 EMR69328.1 - 0.14 11.5 3.6 0.24 10.8 2.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATP_bind_1 PF03029.12 EMR69329.1 - 9.1e-76 254.5 0.0 1.2e-75 254.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 EMR69329.1 - 0.0037 16.0 0.0 0.0075 15.0 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_29 PF13555.1 EMR69329.1 - 0.015 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EMR69329.1 - 0.063 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EMR69329.1 - 0.066 12.6 0.0 0.24 10.8 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.7 EMR69329.1 - 0.074 12.1 0.0 0.28 10.2 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 EMR69329.1 - 0.078 13.8 1.8 0.36 11.6 1.2 2.5 1 1 0 1 1 1 0 AAA domain CDC45 PF02724.9 EMR69330.1 - 0.025 12.6 6.3 0.037 12.0 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.10 EMR69330.1 - 0.043 13.0 3.9 0.074 12.3 2.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Insulin PF00049.13 EMR69330.1 - 0.28 11.9 3.5 0.83 10.4 2.4 1.8 1 1 0 1 1 1 0 Insulin/IGF/Relaxin family Nop14 PF04147.7 EMR69330.1 - 0.43 8.4 14.4 0.58 8.0 10.0 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EMR69330.1 - 0.89 7.9 10.3 1.2 7.5 7.2 1.2 1 0 0 1 1 1 0 Daxx Family Pex14_N PF04695.8 EMR69330.1 - 1.1 9.2 9.2 0.32 11.0 1.4 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CobT PF06213.7 EMR69330.1 - 1.2 8.1 9.2 1.8 7.6 6.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.8 EMR69330.1 - 3 6.4 13.5 4.3 5.9 9.4 1.1 1 0 0 1 1 1 0 Paf1 Aldo_ket_red PF00248.16 EMR69331.1 - 5.9e-61 205.7 0.0 6.7e-61 205.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bac_GDH PF05088.7 EMR69331.1 - 0.19 9.0 0.4 0.27 8.5 0.3 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase MoCF_biosynth PF00994.19 EMR69332.1 - 4.8e-49 165.4 4.6 4.4e-25 87.7 0.1 3.0 3 0 0 3 3 3 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EMR69332.1 - 1.1e-32 112.6 3.4 1.8e-32 111.9 2.3 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EMR69332.1 - 2.3e-14 53.0 0.2 1e-13 51.0 0.0 2.2 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) EamA PF00892.15 EMR69333.1 - 0.011 15.7 1.0 0.013 15.5 0.7 1.1 1 0 0 1 1 1 0 EamA-like transporter family EmrE PF13536.1 EMR69333.1 - 0.03 14.5 0.1 0.037 14.2 0.1 1.1 1 0 0 1 1 1 0 Multidrug resistance efflux transporter Podoplanin PF05808.6 EMR69333.1 - 0.1 12.1 0.2 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Podoplanin RHS_repeat PF05593.9 EMR69333.1 - 5.1 7.4 6.2 1.9 8.7 0.6 2.3 2 0 0 2 2 2 0 RHS Repeat LRR_9 PF14580.1 EMR69334.1 - 1.3e-44 151.8 0.0 2.2e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 EMR69334.1 - 5.3e-10 38.8 8.8 8.4e-07 28.6 1.6 2.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EMR69334.1 - 1.5e-09 37.2 5.2 1.1e-05 24.9 1.4 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EMR69334.1 - 0.00087 19.1 0.2 6.8 7.0 0.4 4.0 4 0 0 4 4 4 1 Leucine Rich repeat LRR_7 PF13504.1 EMR69334.1 - 0.0035 17.2 2.0 3.2 8.3 0.6 4.1 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 EMR69334.1 - 0.021 14.8 5.6 35 4.9 0.4 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat DUF4349 PF14257.1 EMR69334.1 - 0.087 12.0 2.4 0.14 11.3 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) PspB PF06667.7 EMR69334.1 - 0.25 11.2 1.0 0.77 9.7 0.7 1.8 1 0 0 1 1 1 0 Phage shock protein B CBFD_NFYB_HMF PF00808.18 EMR69335.1 - 2.6e-11 43.4 0.1 5.7e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_60s PF00428.14 EMR69335.1 - 0.0013 19.1 14.0 0.0013 19.1 9.7 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein Histone PF00125.19 EMR69335.1 - 0.0015 18.5 0.1 0.003 17.6 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF3123 PF11321.3 EMR69335.1 - 0.049 13.9 3.3 0.12 12.6 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) ProQ PF04352.8 EMR69335.1 - 0.086 12.4 2.0 0.15 11.7 1.4 1.4 1 0 0 1 1 1 0 ProQ/FINO family DUF2413 PF10310.4 EMR69335.1 - 0.091 11.5 4.1 0.11 11.3 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF3708 PF12501.3 EMR69335.1 - 0.11 12.3 3.6 0.17 11.7 2.5 1.4 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter NUC153 PF08159.7 EMR69336.1 - 2.3e-13 49.4 8.2 1.8e-12 46.5 0.8 3.1 2 0 0 2 2 2 2 NUC153 domain Peptidase_A21 PF03566.8 EMR69336.1 - 0.26 9.3 1.0 0.38 8.7 0.7 1.2 1 0 0 1 1 1 0 Peptidase family A21 TFIIA_gamma_N PF02268.11 EMR69337.1 - 1.7e-25 88.3 0.2 2.6e-25 87.7 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EMR69337.1 - 5.8e-25 86.8 0.7 8e-25 86.4 0.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit CM_2 PF01817.16 EMR69338.1 - 3.3e-06 27.0 0.1 0.0014 18.6 0.0 3.0 2 2 0 2 2 2 2 Chorismate mutase type II RCR PF12273.3 EMR69339.1 - 5.5e-05 23.7 0.1 9.1e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red GRP PF07172.6 EMR69339.1 - 0.00047 20.5 4.8 0.00071 20.0 3.0 1.6 1 1 0 1 1 1 1 Glycine rich protein family Herpes_gE PF02480.11 EMR69339.1 - 0.0021 16.4 0.0 0.0023 16.2 0.0 1.0 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1183 PF06682.7 EMR69339.1 - 0.0035 16.9 0.2 0.0047 16.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) CD34_antigen PF06365.7 EMR69339.1 - 0.0045 16.6 0.0 0.0054 16.4 0.0 1.1 1 0 0 1 1 1 1 CD34/Podocalyxin family EphA2_TM PF14575.1 EMR69339.1 - 0.0069 16.7 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4094 PF13334.1 EMR69339.1 - 0.0081 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) DUF4366 PF14283.1 EMR69339.1 - 0.041 13.2 0.0 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DAG1 PF05454.6 EMR69339.1 - 0.055 12.6 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Col_cuticle_N PF01484.12 EMR69339.1 - 0.061 13.0 0.5 0.13 11.9 0.3 1.6 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain m04gp34like PF12216.3 EMR69339.1 - 0.075 12.3 0.1 0.095 12.0 0.1 1.1 1 0 0 1 1 1 0 Immune evasion protein Prominin PF05478.6 EMR69339.1 - 0.088 10.3 0.0 0.097 10.1 0.0 1.0 1 0 0 1 1 1 0 Prominin Protocadherin PF08374.6 EMR69339.1 - 0.092 12.3 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Protocadherin 7tm_1 PF00001.16 EMR69339.1 - 0.11 11.6 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF485 PF04341.7 EMR69339.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Sigma_reg_N PF13800.1 EMR69339.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Shisa PF13908.1 EMR69339.1 - 0.13 12.4 7.5 0.31 11.2 5.2 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator MLANA PF14991.1 EMR69339.1 - 1.1 9.2 3.5 2.2 8.3 2.4 1.6 1 1 0 1 1 1 0 Protein melan-A Cyclin_N PF00134.18 EMR69340.1 - 0.00082 18.9 0.0 0.0045 16.5 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF1810 PF08837.6 EMR69340.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) Thioredoxin PF00085.15 EMR69341.1 - 2e-40 136.6 0.1 4.7e-23 80.8 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EMR69341.1 - 2.6e-12 46.9 0.0 7.5e-05 22.6 0.0 4.2 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EMR69341.1 - 2.6e-08 33.8 0.6 0.0018 18.3 0.0 3.8 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EMR69341.1 - 1.1e-07 32.0 1.6 0.0022 18.1 0.1 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EMR69341.1 - 3.4e-06 26.9 0.5 9.6e-05 22.3 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 EMR69341.1 - 0.0016 18.1 0.7 0.35 10.5 0.0 3.1 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_3 PF13192.1 EMR69341.1 - 0.0019 17.9 0.1 0.072 12.9 0.0 3.3 4 0 0 4 4 4 1 Thioredoxin domain HyaE PF07449.6 EMR69341.1 - 0.011 15.5 0.0 5.7 6.8 0.0 3.1 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 EMR69341.1 - 0.019 14.9 7.9 0.033 14.1 0.2 3.1 3 1 1 4 4 4 0 Thioredoxin Redoxin PF08534.5 EMR69341.1 - 0.16 11.5 0.6 4.5 6.8 0.1 2.5 2 0 0 2 2 2 0 Redoxin PLDc_2 PF13091.1 EMR69342.1 - 4.8e-13 48.9 0.0 3.8e-05 23.4 0.0 3.4 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EMR69342.1 - 1.5e-10 40.5 1.5 0.00011 21.8 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif FANCI_HD2 PF14680.1 EMR69342.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 FANCI helical domain 2 Lactonase PF10282.4 EMR69343.1 - 5.4e-70 236.1 0.0 6.7e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NifT PF06988.6 EMR69343.1 - 0.074 12.5 0.1 0.71 9.3 0.0 2.4 2 0 0 2 2 2 0 NifT/FixU protein SNF2_N PF00176.18 EMR69344.1 - 8.3e-55 185.6 1.8 1.2e-26 93.2 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EMR69344.1 - 1.1e-16 60.4 0.1 4.5e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Voltage_CLC PF00654.15 EMR69345.1 - 1.7e-90 303.6 24.6 1.7e-90 303.6 17.0 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EMR69345.1 - 1.5e-12 47.1 0.4 6.9e-05 22.5 0.1 2.4 2 0 0 2 2 2 2 CBS domain DUF3245 PF11595.3 EMR69346.1 - 0.14 12.3 0.9 0.22 11.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) DUF4611 PF15387.1 EMR69346.1 - 0.19 11.8 1.6 0.32 11.1 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Methyltransf_2 PF00891.13 EMR69347.1 - 6e-31 107.4 0.0 1.1e-30 106.6 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EMR69347.1 - 0.00039 20.1 0.0 0.00078 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR69347.1 - 0.00057 20.4 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMR69347.1 - 0.048 12.7 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_31 PF13847.1 EMR69347.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ParA PF10609.4 EMR69349.1 - 8.2e-36 121.7 0.1 1.4e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EMR69349.1 - 0.00019 20.8 0.9 0.0008 18.8 0.0 2.2 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Pkinase PF00069.20 EMR69350.1 - 1.8e-13 50.2 0.0 2.6e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EMR69350.1 - 8.7e-06 25.4 0.0 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EMR69350.1 - 1.1e-05 25.3 0.1 1.6e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EMR69350.1 - 4.9e-05 22.5 0.0 8.8e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EMR69350.1 - 0.001 18.1 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EMR69350.1 - 0.0028 16.6 0.0 0.0052 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EMR69350.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Spherulin4 PF12138.3 EMR69351.1 - 4.2e-37 127.9 0.0 1.2e-36 126.4 0.0 1.6 1 1 0 1 1 1 1 Spherulation-specific family 4 T5orf172 PF10544.4 EMR69352.1 - 6.7e-14 52.0 0.6 2.8e-13 50.1 0.0 2.3 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.1 EMR69352.1 - 2.6e-12 47.0 0.3 9e-12 45.2 0.2 2.0 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Thymidylate_kin PF02223.12 EMR69353.1 - 5.4e-42 143.2 0.0 1.8e-41 141.5 0.0 1.7 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 EMR69353.1 - 0.00017 21.5 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EMR69353.1 - 0.17 11.0 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SAM_decarbox PF01536.11 EMR69354.1 - 7.1e-85 284.5 0.0 1.7e-62 211.0 0.0 3.9 2 1 0 3 3 3 3 Adenosylmethionine decarboxylase Ribosomal_60s PF00428.14 EMR69354.1 - 0.21 11.9 3.5 0.7 10.3 0.5 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein PTR2 PF00854.16 EMR69355.1 - 1.9e-41 142.0 17.2 1.3e-39 136.0 11.3 2.4 2 1 0 2 2 2 1 POT family RTA1 PF04479.8 EMR69357.1 - 2.3e-50 171.2 5.7 2.3e-50 171.2 3.9 1.3 2 0 0 2 2 2 1 RTA1 like protein Sec62 PF03839.11 EMR69357.1 - 0.34 10.2 2.8 0.92 8.8 2.0 1.7 1 0 0 1 1 1 0 Translocation protein Sec62 Lactonase PF10282.4 EMR69359.1 - 4.3e-22 78.6 2.5 1e-19 70.8 2.1 2.2 1 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller SGL PF08450.7 EMR69359.1 - 0.00096 18.5 0.6 0.011 15.0 0.0 2.6 2 2 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region Tannase PF07519.6 EMR69360.1 - 2e-55 188.3 0.7 2.5e-55 188.0 0.5 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 EMR69360.1 - 0.0019 17.7 0.1 0.0034 16.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR69360.1 - 0.0032 17.3 0.1 0.0041 17.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Y2_Tnp PF04986.8 EMR69361.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative transposase ADH_zinc_N PF00107.21 EMR69362.1 - 3.4e-19 68.6 0.0 5.6e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Histone PF00125.19 EMR69364.1 - 2.2e-22 78.9 0.1 2.8e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMR69364.1 - 4.5e-05 23.4 0.0 6.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF221 PF02714.10 EMR69365.1 - 2.2e-86 289.6 7.9 1.4e-85 287.0 5.4 2.0 1 1 0 1 1 1 1 Domain of unknown function DUF221 DUF3779 PF12621.3 EMR69365.1 - 1.5e-21 76.0 0.1 2.6e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EMR69365.1 - 8.3e-13 48.6 0.3 1.6e-12 47.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RSN1_TM PF13967.1 EMR69365.1 - 6.2e-09 35.5 0.0 1.8e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport SmpA_OmlA PF04355.8 EMR69365.1 - 0.033 13.7 0.1 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 SmpA / OmlA family 4HBT PF03061.17 EMR69366.1 - 2.2e-10 40.5 0.1 3.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EMR69366.1 - 0.045 13.4 0.3 0.1 12.3 0.0 1.7 1 1 1 2 2 2 0 Thioesterase-like superfamily Hce2 PF14856.1 EMR69367.1 - 4e-11 42.6 0.0 5.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Tannase PF07519.6 EMR69369.1 - 5.3e-24 84.7 0.0 5.8e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Fungal_trans PF04082.13 EMR69370.1 - 5.9e-19 67.9 0.1 9.3e-19 67.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pentapeptide PF00805.17 EMR69371.1 - 0.028 13.6 0.0 0.053 12.7 0.0 1.5 1 1 0 1 1 1 0 Pentapeptide repeats (8 copies) DUF99 PF01949.11 EMR69371.1 - 0.12 11.4 1.8 0.16 11.0 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF99 Sulfatase PF00884.18 EMR69372.1 - 2.6e-44 151.6 0.4 3.7e-42 144.5 0.0 2.6 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 EMR69372.1 - 2.3e-07 30.4 0.4 1.5e-06 27.7 0.3 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EMR69372.1 - 0.034 14.4 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase PHO4 PF01384.15 EMR69373.1 - 1.6e-80 270.2 9.5 2e-80 269.8 6.6 1.1 1 0 0 1 1 1 1 Phosphate transporter family PgaD PF13994.1 EMR69373.1 - 0.56 9.6 3.3 1.5 8.3 2.3 1.6 1 0 0 1 1 1 0 PgaD-like protein NAD_binding_8 PF13450.1 EMR69374.1 - 2.5e-10 40.2 0.1 5.6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMR69374.1 - 3.1e-07 29.8 1.1 4.9e-07 29.1 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR69374.1 - 5.5e-06 26.5 0.0 9.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMR69374.1 - 1e-05 24.8 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EMR69374.1 - 3.4e-05 22.8 1.0 4.9e-05 22.3 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMR69374.1 - 8.5e-05 22.8 0.4 0.00025 21.3 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR69374.1 - 8.7e-05 21.5 1.8 0.00016 20.7 1.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR69374.1 - 0.0001 20.9 0.4 0.00017 20.1 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EMR69374.1 - 0.00013 21.1 0.1 0.00031 19.9 0.1 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EMR69374.1 - 0.00067 19.5 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMR69374.1 - 0.052 12.5 0.5 0.098 11.6 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EMR69374.1 - 0.11 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 EMR69374.1 - 0.11 11.3 0.4 0.17 10.7 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ADH_N PF08240.7 EMR69375.1 - 3.9e-07 29.8 0.0 1.3e-06 28.1 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR69375.1 - 0.00051 19.5 0.6 0.002 17.6 0.4 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EMR69375.1 - 0.0025 17.8 1.1 0.0065 16.4 0.4 1.9 2 0 0 2 2 2 1 NADH(P)-binding Acylphosphatase PF00708.13 EMR69375.1 - 0.034 14.2 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 Acylphosphatase Striatin PF08232.7 EMR69376.1 - 2.6e-36 124.9 3.1 5.6e-36 123.8 2.1 1.6 1 0 0 1 1 1 1 Striatin family WD40 PF00400.27 EMR69376.1 - 2.9e-29 99.8 16.0 1.6e-06 27.7 0.0 7.1 6 1 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EMR69376.1 - 0.068 11.4 0.0 0.21 9.8 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain R3H PF01424.17 EMR69377.1 - 2.9e-10 39.6 0.9 6.1e-10 38.6 0.1 2.0 2 0 0 2 2 2 1 R3H domain RRM_6 PF14259.1 EMR69377.1 - 2.8e-06 27.2 0.0 5.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR69377.1 - 1.4e-05 24.8 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR69377.1 - 9.6e-05 21.9 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 EMR69378.1 - 4.6e-18 65.0 20.1 5.1e-17 61.6 13.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR69378.1 - 3.4e-10 39.1 4.3 6.5e-10 38.1 3.0 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EMR69378.1 - 0.0018 16.4 1.3 0.011 13.8 0.9 2.0 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Kinesin PF00225.18 EMR69379.1 - 1.7e-92 309.6 0.0 1.7e-92 309.6 0.0 2.8 3 0 0 3 3 3 1 Kinesin motor domain Aldo_ket_red PF00248.16 EMR69381.1 - 2.9e-72 242.8 0.0 3.3e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Rep-A_N PF04057.7 EMR69382.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain PAT1 PF09770.4 EMR69382.1 - 1.2 7.2 11.1 1.6 6.8 7.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3433 PF11915.3 EMR69383.1 - 8.2e-34 115.6 8.3 1.5e-18 66.7 1.8 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Nop14 PF04147.7 EMR69383.1 - 0.04 11.8 9.0 0.052 11.4 6.2 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EMR69383.1 - 0.11 10.9 8.2 0.15 10.4 5.7 1.1 1 0 0 1 1 1 0 Daxx Family GspH PF12019.3 EMR69383.1 - 1.9 8.6 7.0 8.5 6.5 4.9 2.2 1 1 0 1 1 1 0 Type II transport protein GspH DUF2457 PF10446.4 EMR69383.1 - 4 6.0 17.5 6.1 5.4 12.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 EMR69383.1 - 7.5 5.7 12.9 11 5.1 8.9 1.1 1 0 0 1 1 1 0 SDA1 DUF4066 PF13278.1 EMR69384.1 - 4.1e-24 84.7 0.0 5.1e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EMR69384.1 - 1.7e-12 47.0 0.0 2.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family SlyX PF04102.7 EMR69385.1 - 0.13 12.6 2.0 0.21 11.9 0.5 2.1 2 0 0 2 2 2 0 SlyX FA_hydroxylase PF04116.8 EMR69387.1 - 0.017 15.5 3.6 0.017 15.5 2.5 2.2 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily adh_short PF00106.20 EMR69388.1 - 2.8e-18 66.4 1.1 4.5e-18 65.7 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR69388.1 - 1.5e-10 41.0 0.3 2.5e-10 40.2 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR69388.1 - 0.0018 17.7 0.1 0.0038 16.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EMR69388.1 - 0.0066 16.2 0.1 0.012 15.4 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase CUE PF02845.11 EMR69388.1 - 0.095 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 CUE domain Romo1 PF10247.4 EMR69389.1 - 0.0024 18.0 0.3 1.7 8.8 0.0 2.4 2 0 0 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 DUF1689 PF07954.6 EMR69389.1 - 0.0049 16.7 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) FtsX PF02687.16 EMR69389.1 - 0.018 14.8 0.0 0.05 13.3 0.0 1.7 1 1 0 1 1 1 0 FtsX-like permease family SNARE_assoc PF09335.6 EMR69389.1 - 0.069 13.3 1.1 0.29 11.3 0.1 2.0 2 0 0 2 2 2 0 SNARE associated Golgi protein Fungal_trans PF04082.13 EMR69390.1 - 2.5e-11 42.9 0.1 4.2e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_2 PF00891.13 EMR69391.1 - 4.4e-08 32.6 0.0 5.4e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase NAD_binding_10 PF13460.1 EMR69392.1 - 1.7e-09 37.9 0.1 3.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR69392.1 - 9e-08 31.6 0.0 1.6e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family FIST_C PF10442.4 EMR69392.1 - 0.02 14.8 0.0 0.095 12.6 0.0 2.0 2 0 0 2 2 2 0 FIST C domain adh_short PF00106.20 EMR69392.1 - 0.032 14.1 0.3 0.14 12.1 0.1 1.9 1 1 1 2 2 2 0 short chain dehydrogenase Epimerase PF01370.16 EMR69392.1 - 0.05 13.0 0.0 0.33 10.3 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 EMR69392.1 - 0.11 12.1 0.2 0.48 10.0 0.0 1.9 1 1 0 2 2 2 0 KR domain FAD_binding_4 PF01565.18 EMR69394.1 - 1.4e-29 102.3 1.4 2.8e-29 101.3 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR69394.1 - 3.9e-07 29.8 0.6 8.1e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like Amidohydro_1 PF01979.15 EMR69395.1 - 1.1e-13 51.5 0.3 1.4e-12 47.9 0.2 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMR69395.1 - 8.8e-13 48.9 3.0 2.3e-12 47.5 2.1 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EMR69395.1 - 5.8e-11 42.0 0.0 1.7e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EMR69395.1 - 2.7e-08 33.4 0.5 0.0038 16.4 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family Piwi PF02171.12 EMR69397.1 - 7.3e-61 205.7 0.0 1e-60 205.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EMR69397.1 - 1.3e-08 34.0 0.0 3e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EMR69397.1 - 0.088 12.1 0.0 0.41 9.9 0.0 2.0 1 1 0 1 1 1 0 PAZ domain Porphobil_deam PF01379.15 EMR69398.1 - 5.2e-74 247.7 0.0 7.2e-74 247.3 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EMR69398.1 - 5.1e-17 61.7 0.2 2.2e-16 59.7 0.1 2.0 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain V-set_CD47 PF08204.6 EMR69398.1 - 0.045 13.5 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain adh_short PF00106.20 EMR69399.1 - 2.6e-08 33.9 0.2 4.2e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 EMR69399.1 - 0.0059 16.3 0.2 0.012 15.3 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 EMR69399.1 - 0.022 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 KR domain CDP-OH_P_transf PF01066.16 EMR69400.1 - 7.2e-18 64.7 3.6 7.2e-18 64.7 2.5 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase OMPdecase PF00215.19 EMR69401.1 - 2.7e-96 321.3 0.0 3.1e-96 321.1 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family adh_short_C2 PF13561.1 EMR69402.1 - 3.6e-14 53.1 0.2 2.1e-13 50.6 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR69402.1 - 7.9e-10 38.8 1.1 5.7e-09 36.1 0.8 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR69402.1 - 0.0073 15.9 2.3 1.2 8.7 1.6 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR69403.1 - 3e-17 63.2 0.6 6.7e-17 62.0 0.4 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR69403.1 - 6.6e-14 51.7 0.0 1.1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EMR69403.1 - 1.5e-05 24.1 0.0 2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EMR69403.1 - 1.8e-05 24.3 0.1 5.6e-05 22.6 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR69403.1 - 0.00034 19.4 0.0 0.00055 18.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMR69403.1 - 0.00054 18.9 0.6 0.0013 17.7 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein DapB_N PF01113.15 EMR69403.1 - 0.0089 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EMR69403.1 - 0.02 15.2 0.3 0.045 14.0 0.2 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.14 EMR69403.1 - 0.025 15.0 0.3 0.055 13.9 0.2 1.5 1 0 0 1 1 1 0 CoA binding domain ApbA PF02558.11 EMR69403.1 - 0.043 13.2 0.1 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA KR PF08659.5 EMR69403.1 - 0.074 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 EMR69403.1 - 0.12 12.2 0.2 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EMR69403.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain EthD PF07110.6 EMR69404.1 - 4.6e-13 49.9 0.0 6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 EthD domain MFS_1 PF07690.11 EMR69405.1 - 7.8e-37 126.7 55.1 2.5e-35 121.8 24.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily PqiA PF04403.8 EMR69406.1 - 0.41 10.2 7.8 0.89 9.1 0.1 2.8 3 0 0 3 3 3 0 Paraquat-inducible protein A DUF997 PF06196.7 EMR69406.1 - 7.6 6.1 10.9 0.21 11.1 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF997) DUF4512 PF14975.1 EMR69407.1 - 0.65 10.8 2.3 4.3 8.2 0.0 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) MFS_1 PF07690.11 EMR69408.1 - 2.2e-26 92.4 68.6 3.8e-22 78.4 25.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Polyketide_cyc2 PF10604.4 EMR69409.1 - 0.013 15.6 1.1 0.031 14.4 0.8 1.9 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EMR69409.1 - 0.098 12.6 0.1 0.41 10.6 0.1 2.0 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport adh_short PF00106.20 EMR69410.1 - 2.6e-17 63.2 0.0 4.1e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR69410.1 - 7.7e-14 52.0 0.0 9.9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EMR69410.1 - 2.7e-09 36.6 0.0 0.00029 20.0 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EMR69410.1 - 4.6e-07 30.0 0.3 3.8e-06 27.0 0.0 2.2 3 0 0 3 3 3 1 NADH(P)-binding KR PF08659.5 EMR69410.1 - 3.8e-06 26.6 0.0 6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EMR69410.1 - 0.069 12.3 0.1 0.13 11.4 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family Peptidase_S8 PF00082.17 EMR69411.1 - 3.3e-38 131.4 1.5 4.6e-38 130.9 1.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMR69411.1 - 4.4e-08 33.5 0.0 8.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 zf-RING_2 PF13639.1 EMR69412.1 - 5.8e-07 29.2 0.3 9.4e-07 28.5 0.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMR69412.1 - 0.009 15.6 0.2 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR69412.1 - 0.07 12.8 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.2 EMR69412.1 - 0.2 11.7 0.9 0.55 10.3 0.6 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger 4HBT_3 PF13622.1 EMR69413.1 - 5.8e-37 127.8 0.2 7.2e-37 127.4 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily CLTH PF10607.4 EMR69414.1 - 1.4e-30 105.8 0.0 2.9e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EMR69414.1 - 7.4e-17 60.7 0.6 1.6e-16 59.7 0.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EMR69414.1 - 2.3e-06 27.3 0.2 4.2e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 EMR69414.1 - 3.3e-05 23.2 0.1 6.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 EMR69414.1 - 5.5e-05 23.1 0.6 0.0001 22.2 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMR69414.1 - 0.001 18.6 0.2 0.0018 17.8 0.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR69414.1 - 0.0013 18.3 0.2 0.0023 17.6 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMR69414.1 - 0.0087 15.7 0.5 0.017 14.7 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMR69414.1 - 0.16 12.0 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger WBP-1 PF11669.3 EMR69415.1 - 0.062 13.3 0.6 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 MacB_PCD PF12704.2 EMR69415.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 MacB-like periplasmic core domain DUF3377 PF11857.3 EMR69415.1 - 1.6 8.4 9.3 14 5.4 0.1 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3377) PPP4R2 PF09184.6 EMR69416.1 - 5.7e-10 39.2 0.0 2.2e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 PPP4R2 DUF605 PF04652.11 EMR69416.1 - 3.1 7.0 12.1 3.6 6.8 8.4 1.2 1 0 0 1 1 1 0 Vta1 like ATG16 PF08614.6 EMR69418.1 - 0.024 14.4 1.7 0.044 13.6 0.4 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) MbeD_MobD PF04899.7 EMR69418.1 - 0.49 10.3 6.0 3.2 7.7 4.1 2.3 1 1 0 1 1 1 0 MbeD/MobD like DUF2959 PF11172.3 EMR69418.1 - 1.8 8.3 6.4 0.57 9.9 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) Abhydrolase_6 PF12697.2 EMR69419.1 - 1e-23 84.4 0.0 1.3e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR69419.1 - 1e-15 57.9 0.0 1.8e-13 50.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR69419.1 - 4.8e-08 32.8 0.0 2e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PA14_2 PF10528.4 EMR69421.1 - 3.4e-11 43.0 0.3 3.4e-11 43.0 0.2 1.9 2 1 0 2 2 2 1 GLEYA domain MliC PF09864.4 EMR69421.1 - 0.017 14.8 0.3 0.035 13.8 0.2 1.5 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme LETM1 PF07766.8 EMR69422.1 - 4.5e-105 350.5 0.2 8.4e-105 349.6 0.2 1.4 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EMR69422.1 - 1.1e-05 24.8 0.0 0.019 14.4 0.0 3.2 3 0 0 3 3 3 2 SAP domain PBP1_TM PF14812.1 EMR69423.1 - 0.00022 21.4 2.7 0.00047 20.3 1.8 1.5 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EMR69423.1 - 0.037 13.5 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 EMR69423.1 - 3.4 6.7 4.5 5.4 6.0 3.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Pro_isomerase PF00160.16 EMR69424.1 - 3.3e-46 157.3 0.2 3.7e-46 157.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Apc1 PF12859.2 EMR69426.1 - 3.2e-17 62.6 6.8 1.6e-16 60.4 4.8 2.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 1 YycI PF09648.5 EMR69428.1 - 0.21 11.0 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 YycH protein Pyr_redox PF00070.22 EMR69429.1 - 2.8e-13 50.0 0.9 6.3e-11 42.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR69429.1 - 6.2e-11 42.5 0.0 1.1e-09 38.5 0.0 3.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR69429.1 - 3.5e-07 29.4 0.0 5.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EMR69429.1 - 1.1e-06 28.9 0.6 0.00027 21.0 0.0 3.4 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR69429.1 - 3.9e-05 22.7 0.1 0.065 12.1 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMR69429.1 - 0.005 16.6 0.1 16 5.2 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EMR69429.1 - 0.019 13.9 0.0 0.24 10.2 0.0 2.3 2 1 1 3 3 3 0 Lycopene cyclase protein ApbA PF02558.11 EMR69429.1 - 0.038 13.4 0.3 0.2 11.0 0.0 2.4 3 1 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EMR69429.1 - 0.095 11.3 0.0 0.43 9.1 0.1 1.9 1 1 1 2 2 2 0 Tryptophan halogenase Ribosomal_L10 PF00466.15 EMR69429.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L10 p450 PF00067.17 EMR69430.1 - 0.025 13.0 0.0 0.037 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 Methyltransf_2 PF00891.13 EMR69431.1 - 1.1e-35 122.9 0.0 1.5e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EMR69431.1 - 9.3e-05 22.9 0.0 0.00022 21.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR69431.1 - 0.0036 17.0 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR69431.1 - 0.0058 17.0 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Glyco_hydro_3 PF00933.16 EMR69432.1 - 5e-83 278.5 0.0 7.1e-83 278.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR69432.1 - 1.5e-49 168.6 0.0 1.4e-48 165.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR69432.1 - 6.1e-25 86.9 0.1 1.2e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.13 EMR69432.1 - 0.088 12.8 1.6 0.65 10.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF11 Clathrin PF00637.15 EMR69433.1 - 3.9e-24 84.8 0.5 8e-22 77.3 0.0 3.1 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_1 PF10366.4 EMR69433.1 - 0.00075 19.4 0.3 0.0085 16.0 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 zf-RING_2 PF13639.1 EMR69433.1 - 0.011 15.5 4.5 0.061 13.1 3.1 2.0 1 1 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EMR69433.1 - 0.051 13.3 3.0 0.071 12.8 0.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain TPR_12 PF13424.1 EMR69433.1 - 0.088 12.7 0.3 0.49 10.3 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMR69433.1 - 0.24 11.2 1.8 4.8 7.2 0.2 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat IFT57 PF10498.4 EMR69433.1 - 8.1 5.0 10.5 20 3.7 7.3 1.6 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Acyltransferase PF01553.16 EMR69434.1 - 1.7e-33 114.8 0.0 2.6e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.16 EMR69434.1 - 0.024 14.3 0.0 0.059 13.1 0.0 1.6 2 0 0 2 2 2 0 Endoribonuclease L-PSP Aminotran_1_2 PF00155.16 EMR69435.1 - 7.5e-82 275.1 0.0 9.4e-82 274.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMR69435.1 - 6.8e-06 25.0 0.0 1.6e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EMR69435.1 - 2e-05 23.0 0.0 3.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EMR69435.1 - 0.0038 16.4 0.1 0.007 15.5 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF3405 PF11885.3 EMR69435.1 - 0.0085 14.3 0.0 0.012 13.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DegT_DnrJ_EryC1 PF01041.12 EMR69435.1 - 0.027 13.5 0.5 0.074 12.0 0.3 1.7 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family NAPRTase PF04095.11 EMR69435.1 - 0.14 11.3 0.1 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Isochorismatase PF00857.15 EMR69436.1 - 2.2e-09 37.5 1.9 7.7e-09 35.7 1.3 1.8 1 1 0 1 1 1 1 Isochorismatase family Bac_luciferase PF00296.15 EMR69439.1 - 8e-64 215.6 0.5 9.9e-64 215.3 0.3 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase LrgB PF04172.11 EMR69440.1 - 6.8e-16 58.0 5.9 3.6e-15 55.7 0.3 2.8 3 0 0 3 3 3 2 LrgB-like family ADP_ribosyl_GH PF03747.9 EMR69440.1 - 0.12 12.1 0.9 0.18 11.5 0.7 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Abhydrolase_3 PF07859.8 EMR69441.1 - 4.9e-52 176.5 1.0 6.8e-52 176.0 0.7 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMR69441.1 - 9.4e-09 34.5 0.2 1.4e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EMR69441.1 - 2e-05 23.9 0.1 0.0075 15.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMR69441.1 - 4e-05 23.4 1.2 5.8e-05 22.8 0.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMR69441.1 - 5.9e-05 22.4 0.8 9e-05 21.8 0.2 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase_phd PF10503.4 EMR69441.1 - 0.032 13.4 0.8 0.032 13.4 0.5 2.6 3 1 0 3 3 3 0 Esterase PHB depolymerase AXE1 PF05448.7 EMR69441.1 - 0.039 12.4 0.1 0.06 11.8 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S51 PF03575.12 EMR69442.1 - 6.3e-10 39.0 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 Lysozyme_like PF13702.1 EMR69443.1 - 2.5e-06 27.0 2.0 4.9e-06 26.1 1.4 1.4 1 1 0 1 1 1 1 Lysozyme-like SLT PF01464.15 EMR69443.1 - 0.0027 17.1 0.5 0.0096 15.4 0.3 1.9 1 1 0 1 1 1 1 Transglycosylase SLT domain DUF791 PF05631.9 EMR69444.1 - 1.7e-63 214.4 8.4 2.6e-63 213.8 5.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EMR69444.1 - 6.7e-20 71.0 20.7 6.7e-20 71.0 14.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily AA_permease_2 PF13520.1 EMR69445.1 - 1.6e-11 43.4 16.3 1.6e-11 43.4 11.3 2.7 1 1 1 2 2 2 2 Amino acid permease Cellulase PF00150.13 EMR69446.1 - 4.1e-21 75.4 0.0 5.5e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EMR69446.1 - 7.5e-06 26.3 0.0 1.7e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 EMR69446.1 - 0.0024 17.0 0.0 0.0054 15.9 0.0 1.5 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_2_C PF02836.12 EMR69446.1 - 0.005 15.7 0.0 0.0075 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Acyl-CoA_dh_1 PF00441.19 EMR69447.1 - 1.4e-17 64.1 4.3 2.5e-17 63.3 3.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMR69447.1 - 4.9e-10 38.7 0.4 1.3e-09 37.3 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EMR69447.1 - 4.9e-06 27.1 0.1 1.2e-05 25.8 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Methyltransf_24 PF13578.1 EMR69448.1 - 9.3e-06 26.4 0.0 2.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR69448.1 - 0.00063 20.3 0.0 0.001 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EMR69448.1 - 0.017 14.4 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Baculo_PEP_C PF04513.7 EMR69449.1 - 0.068 12.9 2.5 0.19 11.5 0.7 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF342 PF03961.8 EMR69449.1 - 0.08 11.3 0.3 0.1 10.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin_2 PF14523.1 EMR69449.1 - 0.24 11.4 2.6 0.39 10.7 0.5 2.0 2 0 0 2 2 2 0 Syntaxin-like protein MFS_1 PF07690.11 EMR69450.1 - 2.6e-20 72.4 22.5 3.1e-20 72.1 15.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Atg14 PF10186.4 EMR69451.1 - 0.12 11.2 2.1 0.16 10.9 1.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Lzipper-MIP1 PF14389.1 EMR69451.1 - 0.19 11.8 0.3 0.19 11.8 0.2 1.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 YkyA PF10368.4 EMR69451.1 - 0.97 8.7 6.9 1.3 8.3 4.7 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein bZIP_2 PF07716.10 EMR69451.1 - 3 7.7 10.4 0.39 10.5 2.0 2.3 2 0 0 2 2 2 0 Basic region leucine zipper PBP1_TM PF14812.1 EMR69451.1 - 3.1 8.1 13.2 1.9 8.8 7.6 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ASFV_J13L PF05568.6 EMR69452.1 - 0.011 15.2 5.0 0.011 15.2 3.5 1.7 2 0 0 2 2 2 0 African swine fever virus J13L protein Rib_recp_KP_reg PF05104.7 EMR69452.1 - 0.11 12.9 12.9 2.1 8.8 4.4 2.2 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region IceA2 PF05862.6 EMR69452.1 - 0.14 11.8 0.6 1.4 8.7 0.0 2.7 3 0 0 3 3 3 0 Helicobacter pylori IceA2 protein Acyl_transf_1 PF00698.16 EMR69453.1 - 5.1e-42 144.3 0.0 1e-41 143.3 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EMR69453.1 - 3.5e-38 130.1 0.1 2.6e-37 127.2 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EMR69453.1 - 3.7e-19 69.2 0.3 1.8e-15 57.1 0.0 2.7 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain DUF915 PF06028.6 EMR69453.1 - 0.084 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) SAC3_GANP PF03399.11 EMR69454.1 - 1.9e-62 210.4 2.0 2.9e-62 209.8 1.4 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Abhydrolase_6 PF12697.2 EMR69455.1 - 1.7e-19 70.6 0.4 2.2e-19 70.2 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR69455.1 - 1.6e-09 37.6 0.0 2.2e-09 37.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EMR69455.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Med14 PF08638.6 EMR69456.1 - 1.4e-67 226.7 0.0 3.1e-67 225.6 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 CorA PF01544.13 EMR69457.1 - 2.7e-44 151.3 1.9 1.3e-21 76.9 0.4 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Band_7 PF01145.20 EMR69458.1 - 1e-22 80.9 1.8 1.6e-22 80.2 1.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Peptidase_S8 PF00082.17 EMR69459.1 - 4.6e-45 153.9 3.3 6.4e-45 153.4 2.3 1.2 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EMR69459.1 - 4.8e-06 26.9 0.0 4.6e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) PA PF02225.17 EMR69459.1 - 2.9e-05 23.7 0.0 9.5e-05 22.0 0.0 1.9 1 0 0 1 1 1 1 PA domain Inhibitor_I9 PF05922.11 EMR69459.1 - 0.00035 21.0 0.0 0.00076 19.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 HTH_Tnp_Tc5 PF03221.11 EMR69460.1 - 1.1e-15 57.1 0.7 1.3e-14 53.6 0.1 2.7 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain SH3_1 PF00018.23 EMR69461.1 - 1e-26 92.0 0.0 7.2e-13 47.6 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EMR69461.1 - 7.5e-18 63.8 0.2 7.5e-08 31.8 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 EMR69461.1 - 2.3e-14 53.1 0.0 4.5e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EMR69461.1 - 1.4e-11 43.6 0.0 5.3e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 EMR69461.1 - 1e-09 37.8 0.1 1.8e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 PB1 domain Rad60-SLD PF11976.3 EMR69461.1 - 0.0094 15.6 0.2 0.026 14.1 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like FAM104 PF15434.1 EMR69461.1 - 0.015 15.4 6.8 1.9 8.7 0.0 2.9 2 1 1 3 3 3 0 Family 104 ubiquitin PF00240.18 EMR69461.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Elongin_A PF06881.6 EMR69462.1 - 7.2e-18 64.9 0.7 1.6e-17 63.8 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A EPTP PF03736.12 EMR69464.1 - 9.6e-26 89.2 4.4 1.4e-06 27.9 0.0 7.3 7 0 0 7 7 7 5 EPTP domain EAP30 PF04157.11 EMR69465.1 - 3.8e-60 202.8 0.0 4.8e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Ion_trans PF00520.26 EMR69466.1 - 2.3e-06 27.0 14.4 2.3e-06 27.0 10.0 1.9 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.7 EMR69466.1 - 0.0032 15.9 12.3 0.017 13.5 1.4 2.1 1 1 1 2 2 2 2 Polycystin cation channel Rad21_Rec8_N PF04825.8 EMR69467.1 - 1.1e-38 131.5 0.0 1.7e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EMR69467.1 - 1.1e-07 30.9 0.1 2.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EMR69467.1 - 0.0038 16.8 0.1 0.064 12.8 0.0 2.4 3 0 0 3 3 3 1 ScpA/B protein E1-E2_ATPase PF00122.15 EMR69468.1 - 5.5e-46 156.4 1.6 6.4e-27 94.0 0.0 2.6 1 1 1 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMR69468.1 - 6e-45 152.9 0.2 1.1e-44 152.1 0.1 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMR69468.1 - 9.7e-30 104.5 0.0 4e-29 102.5 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMR69468.1 - 3.1e-14 52.6 0.0 6.4e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMR69468.1 - 7.4e-13 49.0 0.0 2.3e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMR69468.1 - 0.00031 20.3 1.2 0.0043 16.6 0.8 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Thymidylat_synt PF00303.14 EMR69469.1 - 7.7e-112 372.6 0.0 8.8e-112 372.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_2 PF00328.17 EMR69470.1 - 1.5e-24 87.0 0.0 2e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CSTF2_hinge PF14327.1 EMR69471.1 - 1.8e-29 101.6 1.8 4.5e-29 100.3 1.3 1.7 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EMR69471.1 - 5.8e-20 70.7 0.0 9.3e-20 70.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR69471.1 - 8.1e-16 57.7 0.0 2.2e-15 56.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EMR69471.1 - 3.8e-08 32.4 5.5 3.8e-08 32.4 3.8 2.9 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 EMR69471.1 - 8.8e-08 31.8 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 EMR69471.1 - 0.091 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 PAT1 PF09770.4 EMR69471.1 - 0.79 7.8 12.4 0.91 7.6 8.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Abhydrolase_6 PF12697.2 EMR69472.1 - 2.3e-25 89.8 0.3 2.7e-25 89.5 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR69472.1 - 3.5e-17 62.7 0.1 9.5e-17 61.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR69472.1 - 4e-07 29.8 0.0 1.8e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EMR69472.1 - 0.0016 18.7 0.1 0.0027 17.9 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EMR69472.1 - 0.058 12.9 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein PhoPQ_related PF10142.4 EMR69472.1 - 0.06 11.8 0.0 0.084 11.3 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Lipase_3 PF01764.20 EMR69472.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) ubiquitin PF00240.18 EMR69473.1 - 6e-26 89.6 0.1 7e-26 89.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EMR69473.1 - 1.6e-16 59.7 0.2 1.9e-16 59.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMR69473.1 - 0.00017 21.7 0.0 0.00033 20.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EMR69473.1 - 0.084 12.7 0.1 0.23 11.3 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CTDII PF01556.13 EMR69473.1 - 0.1 12.4 0.5 0.29 11.0 0.3 1.7 2 0 0 2 2 2 0 DnaJ C terminal domain MFS_1 PF07690.11 EMR69474.1 - 2.5e-33 115.2 30.3 2.4e-30 105.4 11.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR69474.1 - 1e-10 40.8 13.1 1e-10 40.8 9.1 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EMR69474.1 - 0.00056 18.2 5.0 0.00056 18.2 3.4 1.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.13 EMR69474.1 - 4.1 5.8 8.7 0.21 10.0 2.0 1.7 2 0 0 2 2 2 0 Reduced folate carrier PhzC-PhzF PF02567.11 EMR69475.1 - 3.8e-22 78.8 0.0 5.1e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein KR PF08659.5 EMR69476.1 - 4.6e-50 169.7 0.2 7.7e-50 169.0 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR69476.1 - 9.6e-38 129.7 0.0 1.8e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 EMR69476.1 - 2.8e-18 66.0 0.1 1.2e-16 60.6 0.0 2.2 1 1 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 EMR69476.1 - 7.7e-18 64.3 0.0 2.1e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR69476.1 - 1.4e-11 45.4 0.0 4.4e-11 43.7 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EMR69476.1 - 6.4e-10 39.1 0.2 1.5e-08 34.7 0.0 3.2 3 0 0 3 3 3 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EMR69476.1 - 1.4e-07 31.9 0.0 3.6e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EMR69476.1 - 0.002 17.8 0.0 0.0044 16.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 EMR69476.1 - 0.003 18.1 0.0 0.011 16.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 EMR69476.1 - 0.023 14.1 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.1 EMR69476.1 - 0.037 13.7 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ras PF00071.17 EMR69478.1 - 5.5e-50 168.9 0.0 6.4e-50 168.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR69478.1 - 1.8e-16 60.6 0.0 2.6e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMR69478.1 - 3e-07 29.8 0.0 4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMR69478.1 - 0.0061 15.7 0.0 0.0099 15.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EMR69478.1 - 0.0084 15.2 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EMR69478.1 - 0.019 14.4 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 EMR69478.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EMR69478.1 - 0.073 13.0 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase CVNH PF08881.5 EMR69479.1 - 2e-30 105.0 0.1 3.1e-30 104.4 0.1 1.3 1 0 0 1 1 1 1 CVNH domain LysM PF01476.15 EMR69479.1 - 7.3e-13 48.1 0.0 1.5e-12 47.1 0.0 1.5 2 0 0 2 2 2 1 LysM domain Rick_17kDa_Anti PF05433.10 EMR69479.1 - 0.00021 20.8 19.5 0.00021 20.8 13.5 2.0 2 0 0 2 2 2 1 Glycine zipper 2TM domain DUF533 PF04391.7 EMR69479.1 - 0.0044 16.4 2.1 0.0044 16.4 1.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF533) TraT PF05818.7 EMR69479.1 - 0.031 13.7 0.1 0.055 12.8 0.1 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF697 PF05128.7 EMR69479.1 - 0.09 12.2 0.3 0.17 11.3 0.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF697) SSFA2_C PF14723.1 EMR69479.1 - 0.096 12.4 1.2 0.35 10.6 1.3 1.5 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus Gly-zipper_OmpA PF13436.1 EMR69479.1 - 1.9 8.1 8.8 3.9 7.1 5.9 1.7 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Zip PF02535.17 EMR69479.1 - 2.2 7.2 8.0 2.9 6.7 5.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter APC_CDC26 PF10471.4 EMR69479.1 - 8.3 7.2 10.0 1.5 9.6 3.7 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Aldo_ket_red PF00248.16 EMR69480.1 - 7.8e-71 238.1 0.0 9.3e-71 237.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Far-17a_AIG1 PF04750.9 EMR69481.1 - 7.1e-08 31.8 8.7 7.1e-08 31.8 6.0 1.7 2 0 0 2 2 2 1 FAR-17a/AIG1-like protein MFS_1 PF07690.11 EMR69482.1 - 6.1e-20 71.2 11.5 8.1e-20 70.8 8.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M50 PF02163.17 EMR69482.1 - 0.013 14.4 1.2 0.02 13.8 0.9 1.3 1 0 0 1 1 1 0 Peptidase family M50 DUF2105 PF09878.4 EMR69483.1 - 0.11 12.0 2.4 0.19 11.2 1.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) FA_desaturase PF00487.19 EMR69483.1 - 2.1 7.7 8.6 5.1 6.4 6.0 1.8 1 1 0 1 1 1 0 Fatty acid desaturase NST1 PF13945.1 EMR69485.1 - 1.7e-49 168.4 14.3 1.7e-49 168.4 9.9 4.7 3 2 1 4 4 4 1 Salt tolerance down-regulator Ribosomal_L9_N PF01281.14 EMR69486.1 - 1.9e-10 39.8 0.0 3.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 EMR69486.1 - 0.04 14.0 0.1 0.62 10.1 0.0 2.4 1 1 0 1 1 1 0 Ribosomal protein L9, C-terminal domain Lant_dehyd_N PF04737.8 EMR69486.1 - 0.073 13.1 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus MRP-L28 PF09812.4 EMR69487.1 - 1.6e-07 31.2 0.2 2.3e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Aldedh PF00171.17 EMR69488.1 - 4e-154 513.3 0.1 4.6e-154 513.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Macro_2 PF14519.1 EMR69489.1 - 0.00027 20.1 0.0 0.0013 17.8 0.0 1.9 2 0 0 2 2 2 1 Macro-like domain FAD_binding_3 PF01494.14 EMR69490.1 - 3.1e-15 56.1 0.8 3.7e-14 52.5 0.5 2.3 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EMR69490.1 - 2.2e-09 36.6 0.1 1.4e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR69490.1 - 4e-07 29.2 0.3 5.1e-06 25.6 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR69490.1 - 1.2e-06 28.7 0.1 1e-05 25.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR69490.1 - 1.7e-06 27.9 0.1 5.4e-06 26.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR69490.1 - 4e-06 26.8 0.4 1.1e-05 25.3 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMR69490.1 - 7.1e-06 25.3 0.1 1.4e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR69490.1 - 0.00051 18.6 0.0 0.00076 18.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EMR69490.1 - 0.0022 16.9 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_10 PF13460.1 EMR69490.1 - 0.0042 17.1 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Lycopene_cycl PF05834.7 EMR69490.1 - 0.012 14.6 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EMR69490.1 - 0.02 14.4 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EMR69490.1 - 0.039 13.6 0.1 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EMR69490.1 - 0.043 13.8 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EMR69490.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 EMR69490.1 - 0.083 11.9 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DPBB_1 PF03330.13 EMR69491.1 - 1.5e-09 37.6 0.2 3.1e-09 36.6 0.2 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EMR69491.1 - 0.00077 19.1 0.1 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 EMR69491.1 - 0.11 12.4 0.2 0.29 11.1 0.0 1.8 2 1 0 2 2 2 0 Cerato-platanin DAO PF01266.19 EMR69492.1 - 4.4e-32 111.3 0.0 5.9e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR69492.1 - 1.2e-06 28.4 0.1 3.4e-06 26.9 0.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR69492.1 - 0.0001 22.2 0.0 0.061 13.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR69492.1 - 0.0012 18.6 0.0 0.021 14.6 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMR69492.1 - 0.0014 18.6 0.0 0.39 10.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EMR69492.1 - 0.0028 17.0 0.0 0.006 15.9 0.0 1.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EMR69492.1 - 0.005 16.5 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EMR69492.1 - 0.0052 17.1 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EMR69492.1 - 0.0072 15.7 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EMR69492.1 - 0.0076 16.0 0.0 0.018 14.8 0.0 1.6 2 0 0 2 2 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EMR69492.1 - 0.0084 15.9 0.0 0.029 14.2 0.0 1.9 3 0 0 3 3 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 EMR69492.1 - 0.029 14.3 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.17 EMR69492.1 - 0.048 12.5 0.0 0.45 9.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EMR69492.1 - 0.1 12.1 0.1 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EMR69492.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EMR69492.1 - 0.14 10.5 0.0 2 6.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein F420_oxidored PF03807.12 EMR69492.1 - 0.15 12.4 0.0 1.9 8.9 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF829 PF05705.9 EMR69493.1 - 1.7e-37 129.4 0.2 2.1e-37 129.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Zn_clus PF00172.13 EMR69494.1 - 4.9e-10 39.1 8.8 8.9e-10 38.3 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 EMR69495.1 - 1.5e-71 236.1 7.2 1.5e-25 88.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EMR69495.1 - 8.9e-24 83.4 4.2 4.4e-12 45.9 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EMR69495.1 - 2.7e-20 70.0 8.6 6.2e-07 28.2 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EMR69495.1 - 1.5e-17 61.8 8.3 0.0002 20.9 0.4 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EMR69495.1 - 9.2e-17 59.5 7.6 1.6e-05 24.0 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EMR69495.1 - 2.7e-11 42.9 5.8 4.9e-07 29.2 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EMR69495.1 - 7.1e-07 29.2 1.1 0.0059 16.6 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EMR69495.1 - 0.12 12.0 6.6 4.4 7.1 0.1 3.5 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EMR69495.1 - 0.16 11.6 0.2 8.2 6.1 0.0 2.8 3 0 0 3 3 3 0 EF hand Cyclin_N PF00134.18 EMR69496.1 - 9.7e-12 44.5 0.5 2.3e-11 43.3 0.3 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3080 PF11279.3 EMR69496.1 - 0.01 15.0 4.6 0.01 15.0 3.2 2.3 2 1 0 3 3 3 0 Protein of unknown function (DUF3080) TFIIB PF00382.14 EMR69496.1 - 0.029 14.1 0.3 0.029 14.1 0.2 1.9 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Turandot PF07240.6 EMR69496.1 - 0.082 12.4 1.5 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot WSC PF01822.14 EMR69498.1 - 8e-14 51.3 6.1 8e-14 51.3 4.2 2.4 4 0 0 4 4 4 1 WSC domain Yeast_MT PF11403.3 EMR69498.1 - 1.3 9.1 8.4 4.2 7.5 5.8 1.8 1 0 0 1 1 1 0 Yeast metallothionein Sporozoite_P67 PF05642.6 EMR69498.1 - 3.7 5.2 11.0 2.1 6.0 2.1 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen GCS PF03074.11 EMR69499.1 - 6.3e-152 505.9 0.0 8.5e-151 502.1 0.0 2.0 1 1 0 1 1 1 1 Glutamate-cysteine ligase Het-C PF07217.6 EMR69501.1 - 3.1e-266 884.4 0.0 3.8e-266 884.1 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF904 PF06005.7 EMR69501.1 - 0.15 12.3 0.4 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) HMG_box PF00505.14 EMR69502.1 - 3.6e-08 33.5 0.2 7.3e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMR69502.1 - 2.1e-05 24.8 0.1 7.1e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 HMG-box domain Alpha_GJ PF03229.8 EMR69503.1 - 0.38 11.1 4.3 0.75 10.1 2.9 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J Aldedh PF00171.17 EMR69505.1 - 2.4e-101 339.3 0.6 2e-92 309.9 0.0 3.0 2 1 1 3 3 3 3 Aldehyde dehydrogenase family Amidohydro_1 PF01979.15 EMR69506.1 - 5e-62 210.4 0.9 7.4e-62 209.9 0.6 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EMR69506.1 - 2.2e-53 179.5 3.7 5.1e-53 178.3 2.6 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EMR69506.1 - 3.3e-39 132.7 0.0 7.8e-39 131.5 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 EMR69506.1 - 4.2e-39 132.5 0.1 1.3e-38 131.0 0.1 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EMR69506.1 - 1.7e-06 27.7 3.3 4.5e-06 26.3 2.3 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMR69506.1 - 0.00019 20.8 0.7 0.0014 17.9 0.0 2.4 1 1 0 2 2 2 1 Amidohydrolase family Amidohydro_2 PF04909.9 EMR69506.1 - 0.0088 15.6 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase RINT1_TIP1 PF04437.8 EMR69508.1 - 9.4e-95 317.9 0.0 1.2e-94 317.5 0.0 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family ADIP PF11559.3 EMR69508.1 - 0.033 14.0 3.0 0.084 12.7 2.1 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CRISPR_Cse2 PF09485.5 EMR69508.1 - 0.065 13.2 3.0 0.096 12.7 1.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF4164 PF13747.1 EMR69508.1 - 0.27 11.3 13.9 0.07 13.2 4.1 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4164) HSCB_C PF07743.8 EMR69508.1 - 3.2 8.2 9.2 2.2 8.7 1.5 4.1 4 0 0 4 4 4 0 HSCB C-terminal oligomerisation domain IncA PF04156.9 EMR69508.1 - 7.3 6.1 14.2 4.9 6.6 7.5 2.4 2 1 0 2 2 2 0 IncA protein Peptidase_S49_N PF08496.5 EMR69509.1 - 0.47 10.2 7.5 0.19 11.4 0.4 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Utp12 PF04003.7 EMR69509.1 - 1.1 9.1 5.0 20 5.1 0.2 3.6 3 1 1 4 4 4 0 Dip2/Utp12 Family F-box PF00646.28 EMR69510.1 - 7.1e-05 22.3 0.8 0.00016 21.2 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMR69510.1 - 0.0047 16.6 2.0 0.01 15.5 0.2 2.3 2 0 0 2 2 2 1 F-box-like Rabaptin PF03528.10 EMR69511.1 - 0.0022 17.9 0.6 0.0036 17.1 0.4 1.4 1 0 0 1 1 1 1 Rabaptin FSH1 PF03959.8 EMR69512.1 - 7.8e-26 90.8 0.0 1.1e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EMR69512.1 - 0.00055 19.8 13.8 0.001 18.9 9.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR69512.1 - 0.0033 17.1 2.9 0.0079 15.9 2.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EMR69512.1 - 0.012 15.1 1.2 0.047 13.2 0.3 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EMR69512.1 - 0.032 13.6 0.0 1.1 8.5 0.0 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Tannase PF07519.6 EMR69513.1 - 4.9e-93 312.4 0.1 9.1e-93 311.5 0.0 1.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EMR69513.1 - 0.012 15.4 0.0 0.041 13.7 0.0 1.8 2 1 0 2 2 2 0 Alpha/beta hydrolase family V_ATPase_I PF01496.14 EMR69514.1 - 0.02 12.7 5.5 0.021 12.6 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.1 EMR69514.1 - 0.03 12.7 11.4 0.039 12.4 7.9 1.1 1 0 0 1 1 1 0 AAA domain TraC_F_IV PF11130.3 EMR69514.1 - 0.052 12.9 1.3 0.093 12.1 0.9 1.4 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer Atg14 PF10186.4 EMR69514.1 - 0.053 12.4 13.1 0.081 11.8 9.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ERM PF00769.14 EMR69514.1 - 0.078 12.5 12.5 0.087 12.3 8.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 EMR69514.1 - 0.084 12.0 6.2 0.13 11.4 4.3 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Orbi_VP5 PF00901.12 EMR69514.1 - 0.23 9.6 10.6 0.32 9.1 7.4 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF745 PF05335.8 EMR69514.1 - 0.49 9.8 12.2 1.3 8.4 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) IncA PF04156.9 EMR69514.1 - 0.86 9.1 16.0 1.3 8.5 11.1 1.2 1 0 0 1 1 1 0 IncA protein Syntaxin-6_N PF09177.6 EMR69514.1 - 1 9.7 14.3 0.14 12.5 4.1 2.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.3 EMR69514.1 - 1.6 8.6 16.6 0.6 9.9 6.9 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.11 EMR69514.1 - 1.8 8.8 12.3 1.2 9.3 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 Spc7 PF08317.6 EMR69514.1 - 1.9 7.0 14.6 2.8 6.4 10.0 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 EMR69514.1 - 1.9 7.4 9.9 3.3 6.6 6.9 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 EMR69514.1 - 2 8.0 11.9 3.2 7.3 7.9 1.5 1 1 0 1 1 1 0 Mnd1 family YjcZ PF13990.1 EMR69514.1 - 2.3 7.3 8.9 7.9 5.5 6.1 1.8 1 1 0 1 1 1 0 YjcZ-like protein Fib_alpha PF08702.5 EMR69514.1 - 2.6 8.1 14.8 0.4 10.8 2.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.4 EMR69514.1 - 3.6 7.7 11.1 1.6 8.9 3.1 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.7 EMR69514.1 - 9.5 6.0 12.3 1.6 8.5 3.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4404 PF14357.1 EMR69514.1 - 9.6 6.7 15.0 4.1 7.9 0.7 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) Abhydrolase_6 PF12697.2 EMR69515.1 - 3.9e-25 89.0 2.0 6.7e-24 85.0 1.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR69515.1 - 6.8e-10 38.8 0.0 3.4e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMR69515.1 - 1.5e-08 34.3 0.0 2.9e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EMR69515.1 - 3.2e-07 30.1 0.0 0.0052 16.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Amidohydro_1 PF01979.15 EMR69516.1 - 2e-13 50.6 0.3 3.1e-13 50.1 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMR69516.1 - 2.9e-11 42.9 0.0 6.6e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EMR69516.1 - 8.5e-10 39.1 0.0 3.8e-08 33.7 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMR69516.1 - 1.1e-06 28.1 1.2 0.00055 19.2 0.2 2.9 3 1 0 3 3 3 2 Amidohydrolase family DeoC PF01791.4 EMR69516.1 - 0.043 13.0 0.1 0.085 12.1 0.0 1.5 1 0 0 1 1 1 0 DeoC/LacD family aldolase NAD_binding_2 PF03446.10 EMR69517.1 - 2.6e-28 98.9 0.0 3.7e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMR69517.1 - 3.3e-08 33.6 0.0 6.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EMR69517.1 - 0.00025 21.3 0.0 0.00065 20.0 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.11 EMR69517.1 - 0.0018 18.6 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EMR69517.1 - 0.0027 17.8 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EMR69517.1 - 0.0088 16.0 0.1 0.79 9.7 0.0 2.5 2 1 0 2 2 2 1 TrkA-N domain GFO_IDH_MocA PF01408.17 EMR69517.1 - 0.0098 16.4 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.11 EMR69517.1 - 0.0098 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA OCD_Mu_crystall PF02423.10 EMR69517.1 - 0.077 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Amino_oxidase PF01593.19 EMR69518.1 - 5.4e-08 32.3 0.0 4.7e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMR69518.1 - 1.1e-06 28.5 0.3 2.4e-06 27.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMR69518.1 - 3.4e-06 26.9 0.8 0.01 15.5 0.1 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 EMR69518.1 - 3.8e-05 22.7 1.9 0.0019 17.2 0.4 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMR69518.1 - 0.00049 19.2 0.4 0.002 17.2 0.3 1.8 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EMR69518.1 - 0.0022 16.6 0.1 0.0031 16.2 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.19 EMR69518.1 - 0.0027 16.5 0.3 0.0032 16.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMR69518.1 - 0.0032 17.8 0.3 0.026 14.9 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR69518.1 - 0.022 14.6 1.1 0.024 14.4 0.3 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR69518.1 - 0.057 12.2 0.2 0.1 11.4 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 EMR69518.1 - 0.068 11.6 0.3 0.11 10.8 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF1264 PF06884.6 EMR69519.1 - 6.2e-53 178.7 0.0 7.6e-53 178.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) p450 PF00067.17 EMR69520.1 - 3.1e-47 161.1 0.0 6.4e-47 160.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Brix PF04427.13 EMR69521.1 - 3.8e-38 131.0 0.4 5.1e-38 130.6 0.3 1.2 1 0 0 1 1 1 1 Brix domain CFEM PF05730.6 EMR69522.1 - 2.8e-11 43.0 9.1 4.6e-11 42.3 6.3 1.3 1 0 0 1 1 1 1 CFEM domain NnrU PF07298.6 EMR69522.1 - 0.048 13.0 8.4 4.3 6.6 5.8 3.0 1 1 0 1 1 1 0 NnrU protein adh_short PF00106.20 EMR69523.1 - 4.2e-63 212.2 5.1 8e-33 113.7 1.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EMR69523.1 - 2.7e-31 108.6 0.6 2.7e-16 59.7 0.2 3.1 3 0 0 3 3 3 2 KR domain MaoC_dehydratas PF01575.14 EMR69523.1 - 2.1e-28 98.1 0.0 5e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EMR69523.1 - 2.2e-08 33.9 0.0 2.7e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Epimerase PF01370.16 EMR69523.1 - 0.01 15.2 2.0 1.9 7.8 0.3 2.8 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF4161 PF13722.1 EMR69523.1 - 0.1 12.8 0.4 0.57 10.4 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) IBR PF01485.16 EMR69524.1 - 5.3e-06 26.2 7.1 5.3e-06 26.2 4.9 4.8 4 1 1 5 5 5 2 IBR domain Baculo_IE-1 PF05290.6 EMR69524.1 - 1 9.1 12.6 0.82 9.4 2.4 3.0 3 0 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) FAD_binding_4 PF01565.18 EMR69525.1 - 2.1e-25 88.8 3.3 3.6e-25 88.0 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR69525.1 - 4e-06 26.6 0.6 1.3e-05 24.9 0.2 2.0 2 0 0 2 2 2 1 Berberine and berberine like Glyco_hydro_88 PF07470.8 EMR69526.1 - 8e-59 199.3 4.2 9.7e-59 199.0 2.9 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 EMR69526.1 - 0.021 13.0 0.3 0.026 12.7 0.2 1.1 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) Mgm101p PF06420.7 EMR69527.1 - 8.3e-90 298.6 0.0 1e-89 298.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 BPL_N PF09825.4 EMR69529.1 - 2.1e-139 464.3 0.0 2.6e-139 464.0 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EMR69529.1 - 1.2e-19 70.5 0.0 2.1e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EMR69529.1 - 0.0011 18.6 0.0 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain adh_short PF00106.20 EMR69530.1 - 2.3e-10 40.6 0.3 3.8e-10 39.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR69530.1 - 0.0007 19.3 0.1 0.00099 18.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Rep_fac_C PF08542.6 EMR69531.1 - 4.1e-17 61.9 0.0 8.4e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EMR69531.1 - 9.6e-16 58.1 0.0 1.8e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EMR69531.1 - 1.4e-13 50.8 1.7 1.8e-13 50.4 0.0 2.0 2 1 0 2 2 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EMR69531.1 - 2.1e-08 33.3 0.0 5.5e-07 28.6 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EMR69531.1 - 6.1e-07 29.6 0.1 4.1e-06 26.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMR69531.1 - 3.7e-06 26.5 0.0 9.3e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EMR69531.1 - 6.8e-06 25.8 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR69531.1 - 1.2e-05 25.4 0.0 0.00012 22.1 0.0 2.5 2 2 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 EMR69531.1 - 2.1e-05 24.2 0.0 0.00019 21.0 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EMR69531.1 - 4.2e-05 23.2 0.2 0.00013 21.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EMR69531.1 - 5.1e-05 23.1 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EMR69531.1 - 7.8e-05 21.7 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 EMR69531.1 - 8.5e-05 21.7 0.0 0.00023 20.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 EMR69531.1 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit TIP49 PF06068.8 EMR69531.1 - 0.00025 19.8 0.0 0.39 9.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_3 PF07726.6 EMR69531.1 - 0.00033 20.2 0.1 0.0012 18.4 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EMR69531.1 - 0.00044 19.8 0.0 0.00094 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EMR69531.1 - 0.00076 18.9 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain PhoH PF02562.11 EMR69531.1 - 0.00091 18.5 0.6 1.1 8.4 0.0 2.6 2 1 0 3 3 2 2 PhoH-like protein AAA_28 PF13521.1 EMR69531.1 - 0.0038 17.1 0.1 0.0087 16.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain DEAD PF00270.24 EMR69531.1 - 0.0054 16.2 0.1 0.34 10.3 0.0 2.8 2 1 1 3 3 3 1 DEAD/DEAH box helicase Mg_chelatase PF01078.16 EMR69531.1 - 0.0063 15.7 0.1 0.031 13.4 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EMR69531.1 - 0.0069 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMR69531.1 - 0.0077 15.6 0.0 0.022 14.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EMR69531.1 - 0.0093 14.9 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EMR69531.1 - 0.024 14.0 0.0 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.2 EMR69531.1 - 0.027 13.9 0.1 2.6 7.3 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EMR69531.1 - 0.028 13.8 0.0 0.24 10.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EMR69531.1 - 0.034 14.9 0.0 0.065 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EMR69531.1 - 0.054 13.3 0.0 0.17 11.7 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Lon_2 PF13337.1 EMR69531.1 - 0.067 11.5 0.0 0.15 10.3 0.0 1.5 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease RNA_helicase PF00910.17 EMR69531.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.7 1 1 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 EMR69531.1 - 0.099 11.4 0.0 2.2 7.0 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain Arch_ATPase PF01637.13 EMR69531.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase Thr_synth_N PF14821.1 EMR69532.1 - 0.04 13.9 0.1 12 5.9 0.1 2.3 2 0 0 2 2 2 0 Threonine synthase N terminus AT_hook PF02178.14 EMR69532.1 - 0.71 9.7 26.9 0.073 12.7 2.0 3.5 3 0 0 3 3 3 0 AT hook motif RFX5_DNA_bdg PF14621.1 EMR69532.1 - 9.4 5.7 10.3 2.2 7.8 1.0 2.3 1 1 1 2 2 2 0 RFX5 DNA-binding domain His_Phos_2 PF00328.17 EMR69533.1 - 0.00014 21.3 0.1 0.0057 16.0 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Pyr_redox_3 PF13738.1 EMR69534.1 - 7.3e-17 62.1 0.0 2.2e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR69534.1 - 1.2e-13 50.8 0.0 1.4e-12 47.4 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EMR69534.1 - 9.7e-09 33.9 0.1 6.9e-08 31.1 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.19 EMR69534.1 - 6.5e-06 25.2 0.0 0.59 8.9 0.0 3.1 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMR69534.1 - 5.1e-05 23.0 0.0 0.00028 20.6 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMR69534.1 - 0.08 12.8 0.0 1.4 8.7 0.0 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.6 EMR69535.1 - 3.6e-22 79.0 0.0 6.1e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3659 PF12396.3 EMR69537.1 - 4.2e-179 580.4 122.7 1.3e-23 82.4 1.8 12.4 12 1 0 12 12 12 10 Protein of unknown function (DUF3659) Apolipoprotein PF01442.13 EMR69537.1 - 0.00075 19.0 0.5 0.00075 19.0 0.4 2.7 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EMR69537.1 - 0.012 15.9 14.1 0.42 11.0 1.9 4.0 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.6 EMR69537.1 - 0.051 11.1 0.6 0.098 10.1 0.4 1.3 1 0 0 1 1 1 0 Prominin DUF1107 PF06526.7 EMR69537.1 - 0.13 12.1 0.0 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1107) YtxH PF12732.2 EMR69537.1 - 1.2 9.5 15.3 6.2e+02 0.8 0.0 5.2 2 1 0 2 2 2 0 YtxH-like protein NOB1_Zn_bind PF08772.6 EMR69538.1 - 0.45 10.3 2.5 0.94 9.3 1.7 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Sugar_tr PF00083.19 EMR69539.1 - 9.1e-56 189.3 11.7 1.3e-55 188.7 8.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR69539.1 - 1.7e-08 33.6 19.6 1.7e-08 33.6 13.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR69539.1 - 0.0022 16.4 3.8 0.0022 16.4 2.6 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein PGAP1 PF07819.8 EMR69540.1 - 0.00021 20.9 0.0 0.00055 19.5 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EMR69540.1 - 0.013 15.3 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2305 PF10230.4 EMR69540.1 - 0.099 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) 2OG-FeII_Oxy PF03171.15 EMR69541.1 - 0.00055 20.1 0.0 0.0038 17.4 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EMR69541.1 - 0.09 13.2 1.7 0.3 11.6 1.2 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Acetyltransf_1 PF00583.19 EMR69542.1 - 5.9e-08 32.6 0.0 8.4e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR69542.1 - 1.4e-07 31.5 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR69542.1 - 8e-05 22.3 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EMR69542.1 - 0.00015 21.8 0.0 0.00019 21.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR69542.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Asparaginase_2 PF01112.13 EMR69543.1 - 5e-82 275.1 2.8 6.2e-82 274.8 2.0 1.0 1 0 0 1 1 1 1 Asparaginase TauD PF02668.11 EMR69544.1 - 6.3e-34 117.7 0.0 8.5e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_43 PF04616.9 EMR69546.1 - 0.0018 17.4 0.1 0.014 14.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 HTH_psq PF05225.11 EMR69547.1 - 1e-19 69.8 0.0 1.3e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 helix-turn-helix, Psq domain HTH_Tnp_1 PF01527.15 EMR69547.1 - 1.1e-05 25.3 0.2 0.00026 20.9 0.0 2.7 2 1 0 2 2 2 1 Transposase CENP-B_N PF04218.8 EMR69547.1 - 1.7e-05 24.1 0.0 0.016 14.6 0.0 2.5 2 0 0 2 2 2 2 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.11 EMR69547.1 - 2.6e-05 23.9 0.0 0.0001 22.0 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.1 EMR69547.1 - 7.4e-05 22.2 0.4 0.054 13.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EMR69547.1 - 0.00024 21.0 0.9 0.0045 16.9 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_38 PF13936.1 EMR69547.1 - 0.019 14.4 0.0 1.1 8.9 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EMR69547.1 - 0.024 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 SpoIIID PF12116.3 EMR69547.1 - 0.096 12.6 0.0 5.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Stage III sporulation protein D HTH_7 PF02796.10 EMR69547.1 - 0.12 12.2 0.0 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Glyco_hydro_61 PF03443.9 EMR69548.1 - 1.4e-49 168.8 1.2 1.7e-49 168.6 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Plug_translocon PF10559.4 EMR69548.1 - 0.057 12.9 0.1 0.24 10.9 0.1 2.1 3 0 0 3 3 3 0 Plug domain of Sec61p EthD PF07110.6 EMR69549.1 - 1e-14 55.2 1.2 1.4e-14 54.7 0.8 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.5 EMR69549.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.3 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase FTCD_C PF04961.7 EMR69549.1 - 0.036 13.4 0.8 0.099 12.0 0.3 1.8 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase Nicastrin PF05450.10 EMR69549.1 - 0.05 12.8 0.0 0.052 12.7 0.0 1.1 1 0 0 1 1 1 0 Nicastrin DPPIV_N PF00930.16 EMR69550.1 - 1.1e-103 346.5 4.4 1.5e-103 346.1 3.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EMR69550.1 - 1.9e-38 131.8 1.0 3.1e-38 131.1 0.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMR69550.1 - 5.5e-05 23.1 0.3 0.00022 21.1 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR69550.1 - 8.1e-05 22.4 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_61 PF03443.9 EMR69551.1 - 1.8e-80 269.8 0.2 1.8e-80 269.8 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EMR69551.1 - 4.6e-12 45.3 9.6 1.2e-11 44.0 6.7 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain SOG2 PF10428.4 EMR69551.1 - 0.46 9.0 6.0 0.55 8.8 4.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TB2_DP1_HVA22 PF03134.14 EMR69552.1 - 2.5e-27 94.4 9.3 3.5e-27 93.9 6.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Transket_pyr PF02779.19 EMR69553.1 - 0.062 12.7 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain DUF1996 PF09362.5 EMR69554.1 - 4.2e-89 298.2 0.3 5.3e-89 297.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RNase_H PF00075.19 EMR69555.1 - 2.9e-08 34.1 0.1 1.4e-06 28.7 0.0 2.2 1 1 0 1 1 1 1 RNase H AAA_22 PF13401.1 EMR69556.1 - 0.049 13.7 0.1 1.2 9.2 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EMR69556.1 - 0.11 12.3 0.5 1.3 8.9 0.0 3.0 2 1 1 3 3 3 0 AAA domain FIST PF08495.5 EMR69556.1 - 0.11 11.5 0.1 1.3 8.1 0.0 2.5 3 0 0 3 3 3 0 FIST N domain RRN7 PF11781.3 EMR69556.1 - 0.25 10.8 1.3 0.56 9.7 0.9 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Macoilin PF09726.4 EMR69557.1 - 0.46 8.7 2.1 0.45 8.7 1.4 1.1 1 0 0 1 1 1 0 Transmembrane protein TrbI PF03743.9 EMR69557.1 - 9.7 5.6 11.2 5.8 6.3 2.7 2.5 1 1 1 2 2 2 0 Bacterial conjugation TrbI-like protein DUF3659 PF12396.3 EMR69558.1 - 3.4e-17 61.8 11.1 6.5e-12 44.9 3.9 3.0 2 2 0 2 2 2 2 Protein of unknown function (DUF3659) Lipase_GDSL PF00657.17 EMR69559.1 - 4.6e-06 26.6 0.2 1e-05 25.4 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Chal_sti_synt_N PF00195.14 EMR69560.1 - 7.2e-23 81.0 0.0 1.1e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 EMR69560.1 - 6.4e-21 74.8 0.0 1.2e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.7 EMR69560.1 - 6.4e-06 25.4 0.0 9.2e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 EMR69560.1 - 0.00047 20.1 0.0 0.0015 18.5 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 EMR69560.1 - 0.004 16.7 0.4 0.016 14.8 0.3 2.0 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thioredoxin_6 PF13848.1 EMR69561.1 - 4.5e-17 62.4 0.0 5.8e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain OPT PF03169.10 EMR69562.1 - 5.4e-96 322.4 44.9 6.6e-96 322.1 31.1 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TMEM125 PF15109.1 EMR69562.1 - 4.6 7.3 7.2 0.75 9.9 0.0 3.3 4 0 0 4 4 4 0 TMEM125 protein family Pam16 PF03656.8 EMR69563.1 - 3e-34 117.5 0.1 3.6e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Pam16 TFIIF_alpha PF05793.7 EMR69564.1 - 4 5.6 8.2 5.5 5.2 5.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF605 PF04652.11 EMR69564.1 - 5.5 6.2 26.3 7.6 5.8 18.2 1.1 1 0 0 1 1 1 0 Vta1 like DnaJ PF00226.26 EMR69565.1 - 1.5e-25 88.6 1.1 1.5e-25 88.6 0.8 2.2 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 EMR69565.1 - 4e-10 39.5 2.7 1e-09 38.2 1.9 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EMR69565.1 - 3.9e-08 33.3 4.6 0.00098 19.1 1.1 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EMR69565.1 - 1.1e-07 31.7 7.3 2.3e-07 30.7 1.6 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EMR69565.1 - 9.4e-05 22.4 4.9 0.19 12.1 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EMR69565.1 - 0.00017 21.6 7.1 0.14 12.6 0.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type PSCyt3 PF07627.6 EMR69565.1 - 0.033 14.0 0.2 0.13 12.1 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) DUF2387 PF09526.5 EMR69565.1 - 0.13 12.2 2.5 0.86 9.5 1.7 2.4 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) zf-LYAR PF08790.6 EMR69565.1 - 1.3 8.7 4.4 3.3 7.4 0.3 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.1 EMR69565.1 - 3.4 7.7 5.1 11 6.1 0.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Pyr_redox_dim PF02852.17 EMR69567.1 - 4.7e-41 139.2 0.2 1.6e-40 137.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EMR69567.1 - 2e-26 93.1 11.2 3.5e-25 89.0 7.8 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR69567.1 - 1.6e-20 73.2 2.7 4e-20 72.0 0.7 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR69567.1 - 0.00013 21.9 0.6 0.011 15.7 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR69567.1 - 0.00097 19.2 0.4 2 8.3 0.1 2.5 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR69567.1 - 0.0011 18.0 0.0 0.83 8.5 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EMR69567.1 - 0.0014 17.8 0.2 0.0022 17.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EMR69567.1 - 0.069 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 EMR69567.1 - 0.093 11.6 10.0 0.97 8.2 2.0 3.0 2 1 1 3 3 3 0 FAD dependent oxidoreductase Peptidase_C54 PF03416.14 EMR69568.1 - 1.2e-49 168.9 0.0 5.2e-42 143.8 0.0 2.1 1 1 1 2 2 2 2 Peptidase family C54 SPX PF03105.14 EMR69569.1 - 2.4e-37 129.2 0.0 3.6e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 SPX domain Cys_Met_Meta_PP PF01053.15 EMR69569.1 - 7.1e-35 120.0 0.0 1.2e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme zf-C3HC4 PF00097.20 EMR69569.1 - 1.1e-08 34.5 5.4 2.8e-08 33.2 3.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMR69569.1 - 5.1e-06 26.1 3.1 1.7e-05 24.4 2.2 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EMR69569.1 - 6e-06 25.9 9.1 1.4e-05 24.8 6.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMR69569.1 - 9.9e-06 25.4 8.6 2.6e-05 24.1 5.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMR69569.1 - 1.3e-05 24.7 6.3 1.7e-05 24.3 3.7 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMR69569.1 - 6.6e-05 22.6 7.4 6.6e-05 22.6 5.1 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EMR69569.1 - 0.00021 20.9 5.5 0.00063 19.4 3.8 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Aminotran_1_2 PF00155.16 EMR69569.1 - 0.045 12.7 0.0 0.098 11.5 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II TerY-C PF15616.1 EMR69569.1 - 0.25 11.2 1.5 0.48 10.3 1.0 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-rbx1 PF12678.2 EMR69569.1 - 0.36 10.9 2.3 0.83 9.8 1.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 EMR69569.1 - 0.62 9.8 3.6 1.8 8.3 2.5 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EMR69569.1 - 0.94 9.1 8.0 0.14 11.7 2.6 1.7 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain DZR PF12773.2 EMR69569.1 - 1 9.2 3.5 2.4 8.0 2.5 1.7 1 0 0 1 1 1 0 Double zinc ribbon Complex1_LYR PF05347.10 EMR69570.1 - 5.9e-10 38.8 2.4 9.8e-10 38.0 1.7 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMR69570.1 - 5.5e-08 32.9 1.5 8.8e-08 32.2 1.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like TPR_7 PF13176.1 EMR69570.1 - 0.15 11.9 0.3 0.93 9.4 0.0 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Histone PF00125.19 EMR69571.1 - 8.2e-26 89.9 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMR69571.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMR69572.1 - 9.3e-22 76.9 0.2 1.3e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EMR69572.1 - 3.6e-05 23.7 0.0 9.9e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EMR69572.1 - 0.00021 21.5 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 EMR69572.1 - 0.0043 15.7 2.1 0.0052 15.5 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RP-C PF03428.8 EMR69572.1 - 0.011 15.1 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 EMR69572.1 - 0.029 14.8 0.6 0.039 14.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) R3H PF01424.17 EMR69574.1 - 7.8e-12 44.7 0.0 1.6e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EMR69574.1 - 2.2e-11 43.3 1.7 5.8e-11 41.9 1.1 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EMR69574.1 - 0.0056 16.4 1.0 0.0056 16.4 0.7 2.9 3 0 0 3 3 3 1 DExH-box splicing factor binding site 2-oxoacid_dh PF00198.18 EMR69575.1 - 1.6e-80 269.7 0.1 2.4e-80 269.1 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EMR69575.1 - 1.1e-19 69.7 3.4 2.1e-19 68.9 2.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EMR69575.1 - 0.0051 16.4 0.8 0.015 14.9 0.2 1.8 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 EMR69575.1 - 0.019 15.2 0.8 0.19 12.0 0.3 2.2 1 1 1 2 2 2 0 HlyD family secretion protein DUF3614 PF12267.3 EMR69575.1 - 0.056 13.7 0.0 0.2 11.8 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) PRCC PF10253.4 EMR69575.1 - 0.2 12.3 9.8 0.36 11.4 6.8 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Neisseria_TspB PF05616.8 EMR69575.1 - 0.33 9.2 9.2 0.43 8.9 6.4 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Trypan_PARP PF05887.6 EMR69575.1 - 0.76 9.5 22.7 1.3 8.8 15.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ndc1_Nup PF09531.5 EMR69575.1 - 3.5 5.9 5.2 4.6 5.5 3.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Acyl_transf_3 PF01757.17 EMR69576.1 - 0.045 12.5 0.0 0.065 12.0 0.0 1.4 1 1 0 1 1 1 0 Acyltransferase family AATase PF07247.7 EMR69577.1 - 2.7e-21 75.6 0.0 5.5e-21 74.6 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EMR69577.1 - 2.3e-06 26.6 0.4 4.5e-06 25.7 0.3 1.4 1 0 0 1 1 1 1 Condensation domain Peptidase_S58 PF03576.9 EMR69578.1 - 7e-111 370.5 0.0 8e-111 370.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S58 Chromo PF00385.19 EMR69579.1 - 2.5e-19 68.6 6.5 2.9e-10 39.6 0.9 2.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Fe-ADH PF00465.14 EMR69580.1 - 5.5e-104 347.7 0.0 6.7e-104 347.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EMR69580.1 - 4.3e-14 52.4 0.0 1.3e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EMR69580.1 - 0.00086 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Glyco_hydro_61 PF03443.9 EMR69581.1 - 2.1e-52 178.0 0.0 2.6e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 A2M_N PF01835.14 EMR69581.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 MG2 domain MFS_1 PF07690.11 EMR69582.1 - 1.5e-16 60.0 31.4 2e-08 33.3 7.7 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily SnoaL_2 PF12680.2 EMR69583.1 - 1.5e-06 28.5 0.0 2.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.15 EMR69583.1 - 0.0051 17.1 0.0 0.0092 16.3 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL PF07366.7 EMR69583.1 - 0.022 14.3 0.1 0.23 11.0 0.0 2.0 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase SnoaL_4 PF13577.1 EMR69583.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain DUF3429 PF11911.3 EMR69584.1 - 2.1e-38 131.4 9.3 2.9e-38 131.0 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF1162 PF06650.7 EMR69585.1 - 2.3e-93 312.4 0.0 1.8e-88 296.3 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EMR69585.1 - 1.8e-41 140.3 0.0 7.1e-41 138.4 0.0 2.2 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EMR69585.1 - 3.9e-05 23.7 0.1 0.00063 19.8 0.0 2.8 3 0 0 3 3 3 1 ATG C terminal domain DUF4050 PF13259.1 EMR69586.1 - 1.2e-31 109.1 0.0 4.8e-31 107.2 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF4050) BAF1_ABF1 PF04684.8 EMR69586.1 - 0.22 10.3 16.1 0.5 9.1 11.2 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Med7 PF05983.6 EMR69587.1 - 1.3e-56 190.8 0.0 1.5e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 MED7 protein DUF2017 PF09438.5 EMR69587.1 - 0.6 9.6 5.5 5.3 6.5 0.1 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF2017) Glyco_hydro_18 PF00704.23 EMR69588.1 - 1.2e-96 324.1 6.5 1.4e-96 323.9 4.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hira PF07569.6 EMR69589.1 - 3.8e-35 121.0 0.1 1.5e-34 119.0 0.0 1.9 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 EMR69589.1 - 5.5e-34 114.8 15.5 4.7e-07 29.4 0.0 7.6 6 1 1 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 EMR69589.1 - 8.1e-05 22.1 0.9 15 5.3 0.0 4.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EMR69589.1 - 0.00028 20.6 0.1 2 8.0 0.0 3.6 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EMR69589.1 - 0.019 12.8 0.2 0.11 10.3 0.0 2.1 2 1 1 3 3 3 0 IKI3 family PQQ_2 PF13360.1 EMR69589.1 - 0.024 14.0 0.1 0.058 12.8 0.1 1.7 1 0 0 1 1 1 0 PQQ-like domain MFS_1 PF07690.11 EMR69590.1 - 4.6e-23 81.5 32.1 4.6e-23 81.5 22.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily PsbN PF02468.10 EMR69590.1 - 0.061 12.9 0.6 0.31 10.6 0.4 2.3 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) p450 PF00067.17 EMR69592.1 - 1.5e-05 23.7 0.0 1.6e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EMR69593.1 - 1.6e-15 57.4 0.4 2.7e-15 56.6 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR69593.1 - 1.9e-07 30.9 0.2 3.2e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR69593.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.6 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Glyco_transf_15 PF01793.11 EMR69594.1 - 2.1e-114 381.9 7.4 2.9e-114 381.4 5.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4635 PF15466.1 EMR69594.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) DEAD PF00270.24 EMR69595.1 - 1.8e-40 138.1 0.0 7.4e-40 136.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR69595.1 - 9.2e-23 79.9 0.0 2.3e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EMR69595.1 - 0.00081 18.2 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EMR69595.1 - 0.0053 16.5 0.1 0.11 12.3 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C2H2_jaz PF12171.3 EMR69596.1 - 0.02 15.0 0.2 0.02 15.0 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMR69596.1 - 0.14 12.3 0.3 0.14 12.3 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EMR69596.1 - 0.2 11.8 3.4 0.36 10.9 2.3 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) FtsJ PF01728.14 EMR69597.1 - 6.9e-42 143.4 0.0 9.9e-42 142.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF104 PF01954.11 EMR69597.1 - 0.029 14.4 1.0 0.056 13.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF104 BCCT PF02028.12 EMR69598.1 - 0.00028 19.2 0.0 0.00033 19.0 0.0 1.0 1 0 0 1 1 1 1 BCCT family transporter p450 PF00067.17 EMR69599.1 - 5.3e-56 190.0 1.3 5e-26 91.2 0.1 4.0 1 1 2 3 3 3 3 Cytochrome P450 LAMTOR PF15454.1 EMR69601.1 - 1.7e-16 60.2 0.9 3.4e-16 59.2 0.7 1.5 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator BNR PF02012.15 EMR69601.1 - 1.1e-10 39.6 22.3 0.41 10.6 0.4 9.3 8 0 0 8 8 8 4 BNR/Asp-box repeat BNR_2 PF13088.1 EMR69601.1 - 5.3e-05 22.6 17.9 0.0066 15.7 0.9 5.5 2 2 1 3 3 3 3 BNR repeat-like domain RNase_T PF00929.19 EMR69602.1 - 3.5e-11 43.6 0.0 1.5e-09 38.3 0.0 2.2 2 0 0 2 2 2 1 Exonuclease zf-C2H2_jaz PF12171.3 EMR69602.1 - 8.3e-05 22.6 0.3 0.0067 16.5 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EMR69602.1 - 0.0015 18.7 3.2 0.073 13.4 0.5 3.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-met PF12874.2 EMR69602.1 - 0.023 14.9 2.3 0.72 10.1 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EMR69602.1 - 0.027 14.8 3.0 3.2 8.3 0.3 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMR69602.1 - 0.046 13.6 1.3 0.35 10.8 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DNA_pol_A_exo1 PF01612.15 EMR69602.1 - 0.12 11.8 0.0 0.46 9.9 0.0 1.9 1 1 0 1 1 1 0 3'-5' exonuclease zf-C2HC_2 PF13913.1 EMR69602.1 - 0.42 10.3 3.6 1.5 8.5 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FA_desaturase PF00487.19 EMR69603.1 - 3.1e-38 131.7 22.0 3.8e-38 131.4 15.2 1.0 1 0 0 1 1 1 1 Fatty acid desaturase p450 PF00067.17 EMR69604.1 - 5.7e-26 91.0 0.0 6.8e-26 90.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EMR69605.1 - 1.5e-17 64.0 1.9 2.5e-17 63.2 1.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR69605.1 - 9.8e-09 35.1 1.2 1.6e-08 34.4 0.8 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EMR69605.1 - 0.016 15.2 0.1 0.028 14.5 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 EMR69605.1 - 0.022 14.5 0.1 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ABC2_membrane PF01061.19 EMR69606.1 - 2.8e-79 265.1 61.5 7e-43 146.2 12.6 3.2 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EMR69606.1 - 4.1e-35 119.5 5.3 6.4e-29 99.6 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 EMR69606.1 - 8.2e-34 116.8 0.2 7e-16 58.7 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EMR69606.1 - 2.9e-15 56.1 43.6 7.1e-09 35.1 7.6 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EMR69606.1 - 3.5e-08 33.4 0.0 1.2e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EMR69606.1 - 2.1e-07 30.5 0.2 0.001 18.4 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_21 PF13304.1 EMR69606.1 - 1.1e-05 25.5 0.0 0.083 12.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain cobW PF02492.14 EMR69606.1 - 1.3e-05 24.7 0.3 0.002 17.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EMR69606.1 - 3.5e-05 23.0 0.0 7.7e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMR69606.1 - 0.00017 21.7 0.1 0.28 11.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EMR69606.1 - 0.00019 21.5 0.3 0.03 14.3 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EMR69606.1 - 0.00027 21.7 0.0 0.0057 17.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMR69606.1 - 0.00086 19.0 0.1 0.4 10.4 0.1 2.8 3 0 0 3 3 2 1 Part of AAA domain UPF0079 PF02367.12 EMR69606.1 - 0.00087 18.9 0.7 0.16 11.6 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EMR69606.1 - 0.002 17.9 0.0 0.25 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EMR69606.1 - 0.0025 17.3 0.2 0.037 13.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 EMR69606.1 - 0.0044 16.6 0.5 0.93 9.1 0.1 2.5 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.13 EMR69606.1 - 0.0094 15.4 0.3 5.5 6.4 0.0 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 EMR69606.1 - 0.011 15.7 0.1 0.04 13.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EMR69606.1 - 0.012 14.5 0.0 3 6.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.1 EMR69606.1 - 0.017 15.4 0.1 0.13 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EMR69606.1 - 0.06 13.0 0.0 18 4.9 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 EMR69606.1 - 0.066 13.4 0.1 3.5 7.8 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 EMR69606.1 - 0.12 11.6 0.0 2.1 7.5 0.0 2.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 EMR69606.1 - 0.15 11.5 2.9 5.8 6.2 0.2 2.8 3 0 0 3 3 3 0 AAA-like domain KaiC PF06745.8 EMR69606.1 - 0.16 11.0 0.2 2.8 7.0 0.0 2.2 2 0 0 2 2 2 0 KaiC MMR_HSR1 PF01926.18 EMR69606.1 - 0.18 11.7 0.1 2.9 7.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Septin PF00735.13 EMR69606.1 - 0.24 10.3 0.8 13 4.6 0.1 2.4 2 0 0 2 2 2 0 Septin APC_CDC26 PF10471.4 EMR69606.1 - 9.6 7.0 8.6 0.27 12.0 0.2 2.6 3 0 0 3 3 2 0 Anaphase-promoting complex APC subunit 1 Glyco_hydro_61 PF03443.9 EMR69607.1 - 1.5e-24 86.9 0.0 2e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Nucleoside_tran PF01733.13 EMR69608.1 - 1.2e-16 60.8 9.7 1e-14 54.4 0.1 2.7 2 2 1 3 3 3 2 Nucleoside transporter DUF2561 PF10812.3 EMR69608.1 - 2.8 7.4 7.2 0.9 9.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2561) AA_permease PF00324.16 EMR69609.1 - 1e-94 317.6 42.6 1.2e-94 317.3 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR69609.1 - 8.3e-22 77.3 46.5 1e-21 76.9 32.2 1.1 1 0 0 1 1 1 1 Amino acid permease Ins_P5_2-kin PF06090.7 EMR69610.1 - 2.6e-33 115.3 0.0 4.3e-32 111.4 0.0 2.0 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Peptidase_C21 PF05381.7 EMR69610.1 - 0.046 13.8 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Tymovirus endopeptidase CAP_N PF01213.14 EMR69610.1 - 1.2 8.4 2.7 3.6 6.7 1.2 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF1470 PF07336.6 EMR69610.1 - 2.4 8.5 12.3 13 6.1 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1470) DUF3112 PF11309.3 EMR69611.1 - 2.1 8.1 7.4 0.13 12.0 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) DUF3995 PF13160.1 EMR69611.1 - 6.1 6.9 16.1 1.2 9.1 1.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) Iso_dh PF00180.15 EMR69613.1 - 5.8e-84 282.0 0.0 6.6e-84 281.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.11 EMR69614.1 - 3.1e-37 128.0 32.5 3.9e-37 127.7 21.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 EMR69614.1 - 2.5 8.1 7.9 1.2 9.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DAO PF01266.19 EMR69616.1 - 4.7e-53 180.3 0.0 5.4e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR69616.1 - 2.6e-07 30.9 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR69616.1 - 1.1e-05 25.3 0.0 2.8e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMR69616.1 - 1.2e-05 25.1 0.2 0.0014 18.4 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EMR69616.1 - 3.1e-05 22.9 0.2 0.00071 18.5 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMR69616.1 - 8.9e-05 21.1 0.1 0.14 10.5 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.7 EMR69616.1 - 0.00091 18.2 0.1 0.013 14.4 0.0 2.5 2 1 1 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 EMR69616.1 - 0.0012 18.0 0.0 0.006 15.7 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EMR69616.1 - 0.0022 17.8 0.2 0.026 14.4 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR69616.1 - 0.05 14.0 0.0 5.1 7.5 0.0 2.7 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMR69616.1 - 0.097 11.7 0.5 1.3 8.0 0.0 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMR69616.1 - 0.14 10.7 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_10 PF13460.1 EMR69617.1 - 1.1e-05 25.4 0.0 0.00031 20.8 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Abhydrolase_6 PF12697.2 EMR69618.1 - 9.4e-30 104.1 0.2 3.8e-29 102.2 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR69618.1 - 4e-13 49.4 0.1 1.2e-12 47.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR69618.1 - 9.9e-11 41.5 0.0 1.9e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EMR69618.1 - 2.9e-06 25.9 0.0 4.6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.8 EMR69618.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Laminin_G_3 PF13385.1 EMR69619.1 - 0.035 14.3 0.7 0.056 13.6 0.4 1.5 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Aminotran_3 PF00202.16 EMR69620.1 - 5.7e-96 321.3 0.0 6.7e-96 321.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Cupin_2 PF07883.6 EMR69621.1 - 1.2e-07 31.1 0.1 0.0064 15.9 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 EMR69621.1 - 4.3e-06 26.2 0.0 6.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EMR69621.1 - 0.0053 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EMR69621.1 - 0.072 12.6 0.0 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 Cupin HAD_2 PF13419.1 EMR69622.1 - 9.6e-27 94.3 0.1 1.3e-26 93.9 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR69622.1 - 0.00012 22.5 0.0 0.0002 21.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5CR_dimer PF14748.1 EMR69624.1 - 7e-24 83.9 1.2 1.6e-23 82.7 0.0 2.1 2 1 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EMR69624.1 - 6.3e-10 39.3 2.6 7.5e-10 39.1 0.6 2.1 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EMR69624.1 - 9.4e-05 22.1 1.1 0.0002 21.1 0.4 1.8 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EMR69624.1 - 0.013 14.9 0.1 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EMR69624.1 - 0.09 12.4 0.1 0.22 11.1 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YEATS PF03366.11 EMR69626.1 - 1.2e-22 79.3 0.7 3.2e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 YEATS family Atg14 PF10186.4 EMR69626.1 - 0.11 11.4 0.6 0.15 10.9 0.0 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FlgH PF02107.11 EMR69626.1 - 0.21 11.1 3.1 0.13 11.8 0.4 1.8 2 0 0 2 2 2 0 Flagellar L-ring protein Spore_YtfJ PF09579.5 EMR69626.1 - 0.24 11.2 7.0 0.11 12.3 0.8 2.5 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) Pex14_N PF04695.8 EMR69626.1 - 0.53 10.3 0.0 0.53 10.3 0.0 2.6 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2404 PF10296.4 EMR69627.1 - 0.00049 20.1 0.0 0.0015 18.6 0.0 1.8 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Aldedh PF00171.17 EMR69628.1 - 2.6e-158 527.1 0.1 2.9e-158 527.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EMR69628.1 - 0.003 16.8 0.0 0.28 10.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Gly_rich_SFCGS PF14272.1 EMR69628.1 - 0.058 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Glycine-rich SFCGS DUF2277 PF10041.4 EMR69629.1 - 0.21 11.5 2.5 8 6.5 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2277) Aminotran_1_2 PF00155.16 EMR69631.1 - 3.3e-95 319.0 0.0 3.9e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HAD PF12710.2 EMR69632.1 - 2.8e-17 63.5 0.0 4.4e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR69632.1 - 0.025 14.9 0.0 0.11 12.8 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMR69632.1 - 0.026 14.1 0.0 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMR69632.1 - 0.068 13.3 0.2 1.9 8.6 0.0 2.6 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.3 EMR69633.1 - 0.11 11.0 0.6 0.18 10.3 0.1 1.5 2 0 0 2 2 2 0 Fungal specific transcription factor domain Cyt-b5 PF00173.23 EMR69634.1 - 8.5e-16 57.5 0.0 2.3e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EMR69634.1 - 2.5e-15 56.6 9.9 2.5e-15 56.6 6.9 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Pyr_redox_3 PF13738.1 EMR69635.1 - 6.6e-07 29.5 0.0 7.6e-05 22.8 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR69635.1 - 8.6e-07 29.0 0.0 2.2e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR69635.1 - 0.0048 16.8 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMR69635.1 - 0.04 13.6 0.0 0.42 10.3 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EMR69635.1 - 0.17 10.3 0.1 0.37 9.2 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Asp_protease PF09668.5 EMR69636.1 - 7.6e-54 180.5 0.2 1.4e-53 179.7 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EMR69636.1 - 3.5e-11 43.4 0.1 2.2e-10 40.8 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EMR69636.1 - 8.2e-08 31.9 0.0 1.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EMR69636.1 - 6.8e-07 29.2 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EMR69636.1 - 1.1e-06 28.4 0.1 4.2e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease ubiquitin PF00240.18 EMR69636.1 - 2.5e-06 26.7 0.0 5.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EMR69636.1 - 3.1e-06 26.8 0.1 1e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain RuvA_C PF07499.8 EMR69636.1 - 0.067 13.3 0.1 0.59 10.3 0.0 2.4 2 0 0 2 2 2 0 RuvA, C-terminal domain UN_NPL4 PF11543.3 EMR69636.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 UBA_4 PF14555.1 EMR69636.1 - 0.086 12.3 0.1 0.086 12.3 0.1 1.8 2 0 0 2 2 2 0 UBA-like domain Methyltransf_8 PF05148.10 EMR69637.1 - 1.4e-56 191.5 0.0 1.1e-53 182.0 0.0 3.7 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EMR69637.1 - 1.9e-06 28.2 0.7 4e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR69637.1 - 0.014 15.0 0.1 1.1 8.8 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMR69637.1 - 0.059 13.7 0.2 1.3 9.4 0.1 2.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EMR69637.1 - 0.07 12.8 0.5 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain CDC45 PF02724.9 EMR69637.1 - 2 6.3 13.4 0.34 8.9 5.4 2.0 2 0 0 2 2 2 0 CDC45-like protein MFS_1 PF07690.11 EMR69638.1 - 3.4e-06 26.0 4.1 4.4e-06 25.6 2.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Spc97_Spc98 PF04130.8 EMR69639.1 - 2.5e-129 432.0 1.8 3.6e-129 431.5 1.2 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Proteasome PF00227.21 EMR69640.1 - 1.1e-56 191.1 0.2 1.3e-56 190.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMR69640.1 - 1e-13 50.2 0.0 2.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EMR69640.1 - 0.0037 16.9 0.1 0.099 12.3 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3137) PI3_PI4_kinase PF00454.22 EMR69642.1 - 5e-37 127.6 0.0 7.2e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TFIIF_beta PF02270.10 EMR69644.1 - 1.9e-65 221.3 3.1 2.5e-65 221.0 2.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit ResIII PF04851.10 EMR69645.1 - 6.4e-12 45.6 0.0 1.8e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMR69645.1 - 5.5e-09 35.7 0.0 2.9e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMR69645.1 - 3.2e-08 33.2 0.0 7e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EMR69645.1 - 0.02 13.9 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EMR69645.1 - 0.082 12.4 0.2 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 EMR69646.1 - 8.2e-68 228.3 0.0 1.3e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMR69646.1 - 2e-11 43.6 0.0 4.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EMR69646.1 - 8.5e-07 28.6 2.0 1.6e-06 27.6 1.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EMR69646.1 - 2e-05 24.1 2.1 4.5e-05 23.0 1.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMR69646.1 - 0.00024 21.0 1.9 0.00053 19.9 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMR69646.1 - 0.00026 20.7 2.5 0.00052 19.7 1.7 1.6 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.24 EMR69646.1 - 0.00049 19.6 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.1 EMR69646.1 - 0.00085 18.9 4.0 0.0056 16.3 2.9 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMR69646.1 - 0.0024 17.9 0.5 0.0073 16.4 0.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EMR69646.1 - 0.014 15.2 0.7 0.029 14.1 0.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EMR69646.1 - 0.031 13.8 2.2 0.095 12.2 1.5 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EMR69646.1 - 0.31 10.9 3.1 0.68 9.8 2.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Serinc PF03348.10 EMR69647.1 - 3.7e-162 539.9 7.1 4.6e-162 539.6 4.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) HoxA13_N PF12284.3 EMR69647.1 - 0.2 11.7 1.1 0.29 11.2 0.3 1.6 2 0 0 2 2 2 0 Hox protein A13 N terminal Myb_DNA-binding PF00249.26 EMR69649.1 - 0.00037 20.4 0.0 0.00089 19.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.12 EMR69650.1 - 3.4e-35 120.0 0.2 6.6e-35 119.0 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EMR69650.1 - 5.1e-07 29.6 0.1 8.9e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMR69650.1 - 1e-06 28.7 0.4 2.3e-06 27.6 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3439 PF11921.3 EMR69650.1 - 4.3 7.1 9.4 0.078 12.7 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) bZIP_1 PF00170.16 EMR69651.1 - 8.2e-07 28.8 12.8 8.2e-07 28.8 8.9 2.5 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 EMR69651.1 - 5.5e-05 23.3 12.8 0.00013 22.2 8.5 1.9 1 1 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EMR69651.1 - 0.0018 18.0 12.5 0.0018 18.0 8.7 3.0 2 1 1 3 3 3 1 Basic region leucine zipper Endotoxin_N PF03945.9 EMR69651.1 - 0.067 12.5 4.0 0.23 10.8 3.0 1.7 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain Adeno_E3 PF06040.6 EMR69651.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 protein DUF342 PF03961.8 EMR69651.1 - 1.1 7.6 10.0 1.6 7.0 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 EMR69651.1 - 1.1 8.7 13.7 1.4 8.4 0.5 3.1 2 1 1 3 3 3 0 Septum formation initiator V_ATPase_I PF01496.14 EMR69651.1 - 5.1 4.8 8.7 7.3 4.3 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ETF PF01012.16 EMR69652.1 - 1e-41 142.4 0.5 1.8e-41 141.5 0.1 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EMR69652.1 - 4.4e-36 122.3 0.3 9.5e-36 121.2 0.2 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Sel1 PF08238.7 EMR69653.1 - 2.9e-13 49.9 0.4 1.3e-06 28.8 0.0 2.7 2 0 0 2 2 2 2 Sel1 repeat TraC PF07820.7 EMR69653.1 - 0.0057 16.8 0.0 0.021 15.0 0.0 2.0 1 0 0 1 1 1 1 TraC-like protein YqeY PF09424.5 EMR69654.1 - 7.9e-22 77.6 1.6 9.7e-22 77.3 1.1 1.1 1 0 0 1 1 1 1 Yqey-like protein Mito_carr PF00153.22 EMR69655.1 - 5.4e-64 211.9 3.2 3.2e-22 78.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1d PF00750.14 EMR69656.1 - 6.2e-53 179.8 0.0 1e-52 179.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EMR69656.1 - 7.4e-11 42.0 0.0 1.7e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 DALR anticodon binding domain Nse4_C PF08743.5 EMR69657.1 - 2.6e-30 104.2 0.0 5.1e-30 103.3 0.0 1.5 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EMR69657.1 - 2e-17 62.7 0.0 5.4e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF4618 PF15397.1 EMR69657.1 - 0.0041 16.5 0.3 0.0095 15.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) Nucleo_P87 PF07267.6 EMR69657.1 - 3.6 6.1 6.0 10 4.6 4.0 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3617 PF12276.3 EMR69658.1 - 0.095 12.1 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) zf-P11 PF03854.9 EMR69659.1 - 0.006 16.0 3.4 0.009 15.4 2.4 1.2 1 0 0 1 1 1 1 P-11 zinc finger EGF_CA PF07645.10 EMR69659.1 - 2.7 8.0 5.8 11 6.0 4.0 2.0 1 1 0 1 1 1 0 Calcium-binding EGF domain PI3_PI4_kinase PF00454.22 EMR69660.1 - 9.5e-36 123.4 0.0 1.9e-34 119.2 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3584 PF12128.3 EMR69662.1 - 0.00046 17.6 68.7 0.00046 17.6 47.6 5.5 2 2 2 5 5 5 2 Protein of unknown function (DUF3584) Spc7 PF08317.6 EMR69662.1 - 0.0025 16.5 19.0 0.0025 16.5 13.2 9.1 2 2 8 10 10 10 6 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EMR69662.1 - 0.0033 16.6 6.9 0.0033 16.6 4.8 8.4 2 2 9 11 11 11 8 Reovirus sigma C capsid protein CorA PF01544.13 EMR69662.1 - 0.0039 16.2 9.6 0.0039 16.2 6.7 8.9 3 2 6 10 10 10 3 CorA-like Mg2+ transporter protein IncA PF04156.9 EMR69662.1 - 0.0077 15.8 173.3 0.026 14.1 20.9 10.7 2 2 6 8 8 8 4 IncA protein Fasciclin PF02469.17 EMR69663.1 - 3.3e-48 162.8 0.1 3.9e-27 94.7 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain ATP-synt_C PF00137.16 EMR69664.1 - 5.5e-23 80.6 29.8 1.6e-14 53.5 6.3 2.2 2 0 0 2 2 2 2 ATP synthase subunit C DUF1469 PF07332.6 EMR69666.1 - 4.5 7.0 20.4 6.3 6.5 14.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) CNH PF00780.17 EMR69667.1 - 1.8e-82 276.8 0.0 7.8e-82 274.7 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EMR69667.1 - 1.7e-38 131.6 0.0 3.4e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EMR69667.1 - 1.3e-35 122.8 0.1 3.5e-35 121.4 0.0 1.7 2 0 0 2 2 2 1 RhoGEF domain DEP PF00610.16 EMR69667.1 - 7.2e-15 54.4 0.0 1.4e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) KN_motif PF12075.3 EMR69667.1 - 0.069 12.9 0.1 0.21 11.3 0.1 1.8 1 0 0 1 1 1 0 KN motif DUF4336 PF14234.1 EMR69669.1 - 3.4e-15 56.0 0.0 2e-10 40.3 0.0 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4336) p450 PF00067.17 EMR69670.1 - 2e-40 138.7 0.0 2.3e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EMR69671.1 - 6.1e-41 140.1 1.5 2.5e-27 95.8 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EMR69671.1 - 1.9e-17 63.5 0.9 2.7e-10 40.1 0.1 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EMR69671.1 - 7.9e-14 51.9 0.0 3.2e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR69671.1 - 2.2e-05 24.0 0.3 0.0034 16.8 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DUF2493 PF10686.4 EMR69671.1 - 0.0083 15.6 0.0 0.03 13.8 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2493) AdoHcyase_NAD PF00670.16 EMR69671.1 - 0.029 14.2 3.5 0.18 11.6 0.3 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Polysacc_synt_2 PF02719.10 EMR69671.1 - 0.086 11.7 0.2 0.81 8.5 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.10 EMR69673.1 - 6.8e-33 113.8 0.0 1e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMR69673.1 - 1.6e-21 76.6 0.1 2.4e-21 76.0 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EMR69673.1 - 2.2e-05 24.8 0.0 5.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 EMR69673.1 - 0.0007 18.4 0.0 0.0013 17.6 0.0 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family p450 PF00067.17 EMR69674.1 - 1.1e-43 149.4 0.0 3e-27 95.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Bac_luciferase PF00296.15 EMR69675.1 - 3.3e-59 200.5 0.7 4.5e-59 200.0 0.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase adh_short PF00106.20 EMR69676.1 - 4.2e-17 62.5 0.1 5.7e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR69676.1 - 1.7e-05 24.7 0.0 2.1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR69676.1 - 0.00089 18.9 0.2 0.0021 17.7 0.1 1.7 1 1 0 1 1 1 1 KR domain FAD_binding_3 PF01494.14 EMR69677.1 - 9.1e-32 110.4 0.0 1.9e-31 109.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMR69677.1 - 2.2e-08 33.0 0.7 8.2e-08 31.1 0.1 2.1 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.19 EMR69677.1 - 4e-08 32.5 0.0 5.3e-08 32.1 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EMR69677.1 - 1.8e-07 30.5 0.0 2.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EMR69677.1 - 4e-07 29.2 0.1 1.9e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EMR69677.1 - 6.1e-07 28.8 0.0 9.4e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR69677.1 - 3.2e-06 27.1 0.0 5.4e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR69677.1 - 4.7e-06 26.5 0.1 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMR69677.1 - 0.00024 20.1 0.1 0.00037 19.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 EMR69677.1 - 0.00045 19.2 0.0 0.00069 18.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EMR69677.1 - 0.00064 20.0 0.1 0.014 15.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EMR69677.1 - 0.00066 19.8 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 EMR69677.1 - 0.0017 18.4 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EMR69677.1 - 0.04 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EMR69677.1 - 0.056 12.0 0.0 0.089 11.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 EMR69677.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.19 EMR69677.1 - 0.13 11.3 0.0 0.36 9.8 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Abhydrolase_6 PF12697.2 EMR69678.1 - 2.5e-29 102.8 0.0 3.1e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR69678.1 - 1.4e-18 67.3 0.0 2.2e-18 66.6 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR69678.1 - 4.5e-07 29.7 0.0 2.4e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EMR69678.1 - 0.00035 19.1 0.0 0.00049 18.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.5 EMR69678.1 - 0.0023 17.8 0.0 0.0054 16.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.15 EMR69678.1 - 0.0052 16.2 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 EMR69678.1 - 0.0072 16.1 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase ITAM PF02189.10 EMR69679.1 - 0.00023 21.1 6.3 2.9 8.4 0.1 4.4 2 1 3 5 5 5 5 Immunoreceptor tyrosine-based activation motif RFX_DNA_binding PF02257.10 EMR69679.1 - 0.1 12.7 0.1 16 5.6 0.0 2.4 1 1 1 2 2 2 0 RFX DNA-binding domain NmrA PF05368.8 EMR69680.1 - 9e-08 31.6 0.0 1.5e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family CTP_synth_N PF06418.9 EMR69681.1 - 1.8e-82 276.5 7.9 2e-78 263.2 4.2 2.9 1 1 1 2 2 2 2 CTP synthase N-terminus GATase PF00117.23 EMR69681.1 - 2.4e-50 170.6 0.0 4.6e-50 169.7 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EMR69681.1 - 0.005 16.2 0.1 0.017 14.5 0.1 2.0 2 1 0 2 2 2 1 Peptidase C26 SSF PF00474.12 EMR69682.1 - 5.5e-16 58.1 25.1 5.5e-16 58.1 17.4 2.3 1 1 1 2 2 2 1 Sodium:solute symporter family Rhomboid PF01694.17 EMR69683.1 - 3.3e-23 82.3 6.5 3.3e-23 82.3 4.5 1.6 2 0 0 2 2 2 1 Rhomboid family Pex14_N PF04695.8 EMR69683.1 - 0.0038 17.2 1.7 0.41 10.6 0.0 2.4 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 EMR69683.1 - 1.7 6.7 7.1 2.4 6.3 4.9 1.2 1 0 0 1 1 1 0 Transmembrane protein PhoD PF09423.5 EMR69684.1 - 6.8e-09 34.7 0.1 1.2e-06 27.4 0.1 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase DUF3328 PF11807.3 EMR69685.1 - 2.3e-49 168.0 0.0 2.8e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Aldedh PF00171.17 EMR69686.1 - 4.2e-108 361.6 0.1 5.2e-108 361.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lactamase_B PF00753.22 EMR69687.1 - 1.5e-08 34.5 1.9 2.3e-07 30.6 1.3 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMR69687.1 - 9.9e-07 28.4 0.0 2.3e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMR69687.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Trp_syntA PF00290.15 EMR69689.1 - 5.7e-92 306.9 0.0 1e-91 306.1 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EMR69689.1 - 1.6e-46 158.9 1.4 3.1e-46 158.0 1.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.12 EMR69689.1 - 0.0033 16.7 0.1 1.7 7.7 0.0 2.5 2 0 0 2 2 2 2 PcrB family DUF1674 PF07896.7 EMR69690.1 - 6.1e-16 58.3 0.7 1.3e-15 57.3 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) DUF4646 PF15496.1 EMR69691.1 - 0.00092 19.2 0.0 0.023 14.7 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4646) DUF397 PF04149.7 EMR69691.1 - 0.052 13.1 1.1 0.67 9.5 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF397) RhgB_N PF09284.5 EMR69693.1 - 9.9e-88 293.6 7.7 1.7e-87 292.9 5.3 1.3 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EMR69693.1 - 4.3e-49 166.3 0.0 3.3e-48 163.4 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EMR69693.1 - 3.5e-15 55.8 0.8 1.1e-14 54.3 0.6 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II DUF4278 PF14105.1 EMR69693.1 - 0.12 12.3 2.5 0.44 10.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4278) bZIP_1 PF00170.16 EMR69694.1 - 4.4e-11 42.5 2.1 6.8e-11 41.9 1.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMR69694.1 - 6.4e-09 35.4 4.8 1.1e-08 34.7 3.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EMR69694.1 - 0.0018 18.5 2.4 0.0024 18.1 1.7 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor HAP1_N PF04849.8 EMR69694.1 - 0.004 16.1 1.8 0.0042 16.0 1.2 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF1465 PF07323.7 EMR69694.1 - 0.011 15.3 0.2 0.012 15.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Phlebovirus_NSM PF07246.6 EMR69694.1 - 0.013 14.6 1.0 0.014 14.6 0.7 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M HALZ PF02183.13 EMR69694.1 - 0.035 13.8 0.3 0.07 12.8 0.2 1.6 1 1 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.10 EMR69694.1 - 1.5 8.3 4.6 4.7 6.7 3.1 1.9 1 1 0 1 1 1 0 Septum formation initiator p450 PF00067.17 EMR69695.1 - 1e-27 96.8 0.0 1.3e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ATP-synt_C PF00137.16 EMR69696.1 - 4.5e-18 64.9 13.1 4.5e-18 64.9 9.1 2.0 2 1 1 3 3 3 1 ATP synthase subunit C Amidohydro_4 PF13147.1 EMR69698.1 - 8.7e-24 85.0 0.3 1.2e-23 84.5 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EMR69698.1 - 2.2e-15 57.1 0.0 7.6e-14 52.0 0.0 2.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMR69698.1 - 2.1e-13 49.8 0.1 5.9e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMR69698.1 - 2e-05 23.9 0.3 0.24 10.5 0.0 2.9 2 1 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.15 EMR69698.1 - 0.07 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Fungal_trans PF04082.13 EMR69699.1 - 5.3e-13 48.4 0.0 8.2e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpes_BLLF1 PF05109.8 EMR69700.1 - 0.11 10.4 0.6 0.13 10.1 0.4 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) TPR_11 PF13414.1 EMR69701.1 - 0.003 17.1 1.3 0.008 15.8 0.0 2.3 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EMR69701.1 - 0.46 10.5 2.6 1.5 8.9 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat LysM PF01476.15 EMR69702.1 - 8.6e-16 57.5 0.0 8.4e-05 22.3 0.0 4.7 5 0 0 5 5 5 3 LysM domain Pet127 PF08634.5 EMR69703.1 - 5.3e-120 399.6 5.7 7.8e-120 399.1 2.1 2.2 2 0 0 2 2 2 1 Mitochondrial protein Pet127 Spc97_Spc98 PF04130.8 EMR69704.1 - 2.4e-35 121.8 0.6 1.3e-34 119.4 0.5 1.8 2 0 0 2 2 2 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 EMR69704.1 - 0.0024 16.0 1.2 0.0034 15.5 0.8 1.2 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 PSDC PF12588.3 EMR69705.1 - 3.2e-51 172.6 0.0 4.6e-51 172.1 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EMR69705.1 - 1.9e-33 115.4 0.0 2.7e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 EMR69705.1 - 0.00064 19.3 0.7 0.26 10.9 0.2 2.4 2 0 0 2 2 2 2 Biotin-lipoyl like F-box-like PF12937.2 EMR69706.1 - 1.3e-05 24.8 0.2 3.8e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EMR69706.1 - 0.0069 16.0 3.2 0.25 11.0 1.0 3.2 2 1 0 2 2 2 1 F-box domain FMN_dh PF01070.13 EMR69707.1 - 3.2e-84 282.8 2.8 9e-49 166.2 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 EMR69707.1 - 0.011 14.6 0.0 0.021 13.7 0.0 1.5 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EMR69707.1 - 0.029 13.3 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.16 EMR69707.1 - 0.039 12.9 0.1 7.5 5.4 0.0 2.8 2 1 0 3 3 3 0 Dihydroorotate dehydrogenase ThiG PF05690.9 EMR69707.1 - 0.054 12.5 1.7 4 6.4 0.0 2.6 2 1 0 3 3 3 0 Thiazole biosynthesis protein ThiG Peptidase_M19 PF01244.16 EMR69707.1 - 0.08 11.8 0.0 0.29 10.0 0.0 1.8 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) APH PF01636.18 EMR69708.1 - 8.1e-12 45.3 0.1 1.6e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Adap_comp_sub PF00928.16 EMR69709.1 - 1.6e-77 260.1 0.0 2.3e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EMR69709.1 - 5.2e-05 22.9 0.1 9.7e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 EMR69709.1 - 0.021 14.6 0.1 0.048 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) Rotavirus_VP1 PF12289.3 EMR69710.1 - 0.029 14.0 0.0 0.086 12.4 0.0 1.7 1 0 0 1 1 1 0 Rotavirus VP1 structural protein PAP2_3 PF14378.1 EMR69711.1 - 2.6e-05 23.8 13.1 0.00061 19.3 0.2 3.3 2 2 1 3 3 3 2 PAP2 superfamily Glyco_hydro_61 PF03443.9 EMR69712.1 - 1.1e-73 247.6 1.2 1.2e-73 247.4 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Big_3_4 PF13754.1 EMR69712.1 - 0.075 13.3 0.7 0.38 11.0 0.1 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Guanylate_kin PF00625.16 EMR69713.1 - 6.6e-60 201.6 0.0 7.4e-60 201.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 EMR69713.1 - 6e-06 26.1 0.0 1.6e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMR69713.1 - 1.7e-05 25.1 0.0 3.6e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR69713.1 - 6.8e-05 22.9 0.0 0.00012 22.1 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EMR69713.1 - 0.00057 20.7 0.0 0.001 19.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMR69713.1 - 0.0023 18.0 0.1 0.0056 16.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMR69713.1 - 0.003 16.7 0.0 0.0071 15.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EMR69713.1 - 0.023 14.9 0.0 0.04 14.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EMR69713.1 - 0.039 13.8 0.2 0.29 11.0 0.0 2.1 2 1 1 3 3 3 0 AAA domain DUF1895 PF08988.5 EMR69713.1 - 0.076 13.0 0.2 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) AAA_24 PF13479.1 EMR69713.1 - 0.16 11.5 0.3 2.6 7.5 0.1 2.1 1 1 0 2 2 2 0 AAA domain cwf21 PF08312.7 EMR69713.1 - 0.38 10.6 3.0 0.69 9.8 2.0 1.3 1 0 0 1 1 1 0 cwf21 domain 4HBT_2 PF13279.1 EMR69714.1 - 4.3e-22 78.8 0.1 6.3e-22 78.2 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Sec5 PF15469.1 EMR69714.1 - 0.051 13.3 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 4HBT PF03061.17 EMR69714.1 - 0.071 13.2 0.0 0.17 11.9 0.0 1.8 1 1 0 1 1 1 0 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EMR69714.1 - 0.075 11.9 0.1 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 Acyl-ACP thioesterase Ank_2 PF12796.2 EMR69715.1 - 3.5e-10 40.0 0.0 2.7e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMR69715.1 - 3.8e-08 32.7 0.4 0.00018 21.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EMR69715.1 - 9.4e-07 28.8 0.1 5.9e-05 23.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR69715.1 - 3.4e-05 23.6 0.2 0.07 13.4 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 EMR69715.1 - 0.00017 21.9 0.0 0.0037 17.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) YppF PF14178.1 EMR69715.1 - 0.063 12.8 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 YppF-like protein Glyco_hydro_18 PF00704.23 EMR69717.1 - 9.3e-76 255.4 4.1 1.6e-75 254.7 2.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EMR69717.1 - 2.9e-11 43.1 12.2 1.5e-10 40.9 8.5 2.3 1 0 0 1 1 1 1 Chitin recognition protein Glycogen_syn PF05693.8 EMR69718.1 - 0 1069.9 0.5 5.2e-256 850.9 0.0 2.0 1 1 1 2 2 2 2 Glycogen synthase Glycos_transf_1 PF00534.15 EMR69718.1 - 7.1e-06 25.5 0.0 0.026 13.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Dehyd-heme_bind PF09098.5 EMR69718.1 - 0.1 12.0 0.3 0.23 10.8 0.1 1.6 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Beta-lactamase PF00144.19 EMR69719.1 - 1.2e-46 159.3 0.0 2.1e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EMR69719.1 - 2.9e-05 23.8 0.1 6.5e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Exo_endo_phos PF03372.18 EMR69720.1 - 1.2e-19 71.2 0.2 1.6e-19 70.8 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EMR69720.1 - 7.5e-15 54.1 8.4 9.1e-11 41.1 1.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMR69720.1 - 7.3e-08 32.0 8.2 4.4e-07 29.5 1.5 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EMR69720.1 - 6.5e-07 28.5 10.9 0.0066 16.3 0.0 4.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EMR69720.1 - 0.00011 21.7 9.4 0.34 11.2 0.1 4.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EMR69720.1 - 0.04 13.9 5.3 0.14 12.3 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Fasciclin PF02469.17 EMR69722.1 - 5.1e-23 81.4 0.5 9.2e-18 64.4 0.0 3.3 2 1 0 2 2 2 2 Fasciclin domain VGCC_beta4Aa_N PF12052.3 EMR69723.1 - 0.032 14.0 0.5 0.094 12.5 0.4 1.8 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal F-box-like PF12937.2 EMR69724.1 - 2.3e-13 49.6 2.2 5.9e-13 48.3 1.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 EMR69724.1 - 1.8e-09 36.6 24.6 3.3 8.0 0.3 11.7 14 0 0 14 14 14 3 Leucine Rich repeat LRR_4 PF12799.2 EMR69724.1 - 1.3e-07 31.0 13.1 0.69 9.6 0.0 6.9 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMR69724.1 - 5.7e-06 25.9 16.6 0.34 10.7 0.1 6.2 3 1 4 7 7 7 4 Leucine rich repeat F-box PF00646.28 EMR69724.1 - 0.00026 20.5 0.9 0.00026 20.5 0.6 2.4 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.28 EMR69724.1 - 0.057 13.4 31.9 6.5 7.1 0.1 10.1 8 3 1 9 9 9 0 Leucine Rich Repeat Hydrolase PF00702.21 EMR69725.1 - 1.3e-16 61.7 0.0 4.6e-16 59.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EMR69725.1 - 4.1e-16 58.7 0.0 1.1e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EMR69725.1 - 1.7e-09 38.0 0.0 4.7e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMR69725.1 - 1.7e-05 24.6 0.0 5.4e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EMR69725.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase WD40 PF00400.27 EMR69726.1 - 6.3e-29 98.7 9.2 7.9e-08 31.8 0.4 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EMR69726.1 - 0.0007 17.8 1.2 0.4 8.7 0.0 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ PF01011.16 EMR69726.1 - 0.00099 18.5 0.4 0.61 9.7 0.0 3.6 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.1 EMR69726.1 - 0.87 9.9 5.7 24 5.3 0.1 4.0 4 1 0 4 4 4 0 PQQ-like domain Methyltransf_23 PF13489.1 EMR69727.1 - 1.7e-09 37.5 0.0 3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR69727.1 - 1.6e-06 28.4 0.0 3.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR69727.1 - 3.3e-06 27.1 0.0 1.7e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR69727.1 - 8.7e-06 26.2 0.0 2.7e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR69727.1 - 1.2e-05 25.6 0.0 2.9e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR69727.1 - 0.002 17.7 0.0 0.0069 15.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR69727.1 - 0.0038 17.6 0.0 0.026 14.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR69727.1 - 0.0085 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EMR69727.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 EMR69727.1 - 0.042 14.6 0.0 0.21 12.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.14 EMR69727.1 - 0.057 12.9 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HD PF01966.17 EMR69728.1 - 1.1e-06 28.6 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 HD domain LysM PF01476.15 EMR69729.1 - 7.1e-31 105.8 11.6 3.7e-07 29.9 0.0 5.4 5 0 0 5 5 5 5 LysM domain Cul7 PF11515.3 EMR69729.1 - 9.1e-08 31.9 0.1 0.6 10.0 0.0 4.2 4 0 0 4 4 4 3 Mouse development and cellular proliferation protein Cullin-7 HTH_Tnp_1 PF01527.15 EMR69729.1 - 2.8e-05 23.9 0.1 0.52 10.2 0.0 4.1 4 0 0 4 4 4 1 Transposase HTH_28 PF13518.1 EMR69729.1 - 0.00028 20.8 0.2 11 6.1 0.0 4.0 4 0 0 4 4 4 2 Helix-turn-helix domain DXP_synthase_N PF13292.1 EMR69729.1 - 0.098 11.5 0.6 18 4.1 0.0 3.0 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase Pox_A11 PF05061.8 EMR69729.1 - 0.78 8.7 2.1 77 2.2 0.0 3.5 4 0 0 4 4 4 0 Poxvirus A11 Protein Glyco_transf_15 PF01793.11 EMR69730.1 - 1.9e-138 460.9 8.2 2.3e-138 460.6 5.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GDI PF00996.13 EMR69731.1 - 5.9e-181 601.5 0.0 6.9e-181 601.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor zf-CCHC PF00098.18 EMR69732.1 - 0.00019 21.2 4.9 0.00021 21.0 2.4 1.9 2 0 0 2 2 2 1 Zinc knuckle BAH PF01426.13 EMR69733.1 - 3.8e-06 26.6 0.1 8.9e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 BAH domain PHD PF00628.24 EMR69733.1 - 0.0015 18.1 2.8 0.0015 18.1 1.9 2.2 2 0 0 2 2 2 1 PHD-finger Epimerase PF01370.16 EMR69734.1 - 1.5e-23 83.4 0.0 2.1e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EMR69734.1 - 9.2e-10 37.8 0.0 2e-09 36.7 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EMR69734.1 - 9.2e-07 29.0 0.0 2.1e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMR69734.1 - 2.1e-06 27.7 0.0 5.4e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EMR69734.1 - 3.8e-06 26.0 0.0 1e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EMR69734.1 - 3.6e-05 22.6 0.0 5.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EMR69734.1 - 0.0012 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 EMR69734.1 - 0.0037 17.2 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 EMR69734.1 - 0.02 13.7 0.0 0.043 12.7 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 EMR69734.1 - 0.037 13.8 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain WSN PF02206.13 EMR69734.1 - 0.085 12.6 0.1 0.69 9.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function ATG22 PF11700.3 EMR69736.1 - 2.5e-72 243.9 5.9 2.8e-72 243.7 4.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EMR69736.1 - 0.008 14.9 14.3 0.064 11.9 10.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EMR69736.1 - 0.17 10.2 3.4 0.17 10.2 1.6 1.4 1 1 0 1 1 1 0 MFS/sugar transport protein SH3_1 PF00018.23 EMR69737.1 - 3.5e-12 45.4 0.1 5.9e-12 44.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMR69737.1 - 9.9e-08 31.4 0.1 1.8e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMR69737.1 - 1e-07 31.3 0.0 1.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3425 PF11905.3 EMR69738.1 - 1e-15 57.8 5.5 5.6e-15 55.4 3.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EMR69738.1 - 4.7 7.2 12.4 9.2 6.3 8.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor Metal_resist PF13801.1 EMR69739.1 - 0.0006 19.7 2.5 0.0013 18.7 1.7 1.6 1 1 0 1 1 1 1 Heavy-metal resistance DUF2019 PF09450.5 EMR69739.1 - 0.044 13.6 0.2 0.18 11.6 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2019) Ribosomal_S17e PF00833.13 EMR69740.1 - 9.1e-57 190.1 0.3 1.1e-56 189.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EMR69740.1 - 0.0035 18.0 0.1 0.0053 17.4 0.0 1.2 1 0 0 1 1 1 1 Blue/Ultraviolet sensing protein C terminal NmrA PF05368.8 EMR69741.1 - 5.3e-40 137.1 0.0 9.9e-40 136.2 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR69741.1 - 4.8e-10 39.7 0.1 7.8e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMR69741.1 - 8.8e-06 24.6 0.0 1.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMR69741.1 - 0.00098 19.0 0.7 0.0015 18.4 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EMR69741.1 - 0.0014 18.1 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EMR69741.1 - 0.049 13.9 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MRP-L47 PF06984.8 EMR69743.1 - 1.5e-24 85.6 1.8 2.2e-24 85.1 1.3 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) priB_priC PF07445.7 EMR69743.1 - 0.046 13.1 1.7 0.071 12.5 1.2 1.2 1 0 0 1 1 1 0 Primosomal replication protein priB and priC Clc-like PF07062.7 EMR69743.1 - 0.16 11.1 1.1 0.27 10.4 0.8 1.3 1 0 0 1 1 1 0 Clc-like DLH PF01738.13 EMR69744.1 - 3.4e-07 29.7 0.0 3.9e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMR69744.1 - 0.015 15.0 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1681 PF07933.9 EMR69745.1 - 5.9e-55 185.2 0.0 8.1e-55 184.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SH3_2 PF07653.12 EMR69745.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain His_Phos_1 PF00300.17 EMR69746.1 - 1.9e-17 63.8 3.2 3.2e-15 56.5 0.2 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Secretin_N_2 PF07655.8 EMR69746.1 - 3 8.2 7.2 2.2 8.7 3.3 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain RPAP2_Rtr1 PF04181.8 EMR69749.1 - 1.9e-11 43.8 0.0 4.6e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Rtr1/RPAP2 family TEX19 PF15553.1 EMR69749.1 - 0.19 11.5 2.4 0.35 10.7 1.5 1.5 1 1 0 1 1 1 0 Testis-expressed protein 19 HNF-1_N PF04814.8 EMR69749.1 - 0.2 11.7 2.7 0.37 10.8 1.9 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Spc97_Spc98 PF04130.8 EMR69751.1 - 4.1e-72 243.2 0.0 6e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Mit_ribos_Mrp51 PF11709.3 EMR69752.1 - 1.3e-82 277.5 0.2 1.5e-82 277.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit zf-H2C2_2 PF13465.1 EMR69753.1 - 6e-08 32.5 6.7 1e-05 25.5 0.8 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EMR69753.1 - 2.5e-05 24.2 14.2 0.0012 19.0 4.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EMR69753.1 - 0.0011 19.0 3.8 0.0024 17.9 2.6 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Fungal_trans PF04082.13 EMR69753.1 - 0.0012 17.7 0.2 0.0023 16.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EMR69753.1 - 0.014 15.6 16.8 0.041 14.2 4.7 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EMR69753.1 - 0.42 10.8 3.6 6.4 7.0 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EMR69753.1 - 1.9 8.3 7.8 0.95 9.2 0.9 2.5 2 0 0 2 2 2 0 BED zinc finger DUF3848 PF12959.2 EMR69754.1 - 0.043 13.7 2.7 2.2 8.2 0.1 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF3848) Senescence PF06911.7 EMR69755.1 - 2.6e-46 157.5 6.1 4.1e-46 156.9 4.2 1.3 1 0 0 1 1 1 1 Senescence-associated protein DUF3910 PF13049.1 EMR69755.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3910) F_actin_cap_B PF01115.12 EMR69756.1 - 1e-96 322.8 0.0 1.6e-96 322.1 0.0 1.3 1 1 0 1 1 1 1 F-actin capping protein, beta subunit Pyr_redox_2 PF07992.9 EMR69757.1 - 1.5e-13 51.1 0.0 2e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MAM33 PF02330.11 EMR69758.1 - 1.4e-31 109.8 1.4 1.9e-31 109.3 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF963 PF06131.6 EMR69758.1 - 1.1 8.6 5.5 0.26 10.5 0.4 2.2 1 1 1 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) FRQ PF09421.5 EMR69759.1 - 8.8e-164 546.8 35.2 1.2e-163 546.4 24.4 1.1 1 0 0 1 1 1 1 Frequency clock protein Transferase PF02458.10 EMR69760.1 - 1.3e-10 40.3 0.1 8.7e-06 24.4 0.0 2.3 2 0 0 2 2 2 2 Transferase family Condensation PF00668.15 EMR69760.1 - 0.0017 17.2 0.2 0.0017 17.2 0.2 1.6 2 0 0 2 2 2 1 Condensation domain Mucin PF01456.12 EMR69760.1 - 0.073 12.8 22.8 0.13 12.0 15.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.3 EMR69760.1 - 0.098 11.8 12.0 0.13 11.4 8.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Dicty_REP PF05086.7 EMR69760.1 - 5.2 4.6 4.6 6.8 4.3 3.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1237 PF06824.6 EMR69761.1 - 8.1e-22 77.4 0.6 1.7e-21 76.3 0.0 1.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1237) ISG65-75 PF11727.3 EMR69762.1 - 0.047 12.7 7.4 0.053 12.5 5.2 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DivIVA PF05103.8 EMR69762.1 - 0.052 13.6 1.9 0.072 13.1 1.3 1.3 1 1 0 1 1 1 0 DivIVA protein DUF883 PF05957.8 EMR69762.1 - 0.68 10.3 8.1 0.54 10.6 2.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CsbD PF05532.7 EMR69762.1 - 2.9 7.6 16.9 22 4.7 7.1 3.1 1 1 1 2 2 2 0 CsbD-like DUF1744 PF08490.7 EMR69763.1 - 1.3e-154 514.5 0.0 1.9e-154 514.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EMR69763.1 - 6.6e-55 186.2 0.0 1.2e-54 185.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EMR69763.1 - 8.7e-23 80.8 0.1 2.9e-22 79.0 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EMR69763.1 - 2.8e-07 30.2 0.1 8.3e-07 28.7 0.1 1.7 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EMR69763.1 - 0.00021 21.1 0.0 0.00075 19.3 0.0 2.0 2 0 0 2 2 2 1 RNase_H superfamily DNA_pol3_alpha PF07733.7 EMR69763.1 - 0.061 11.7 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit IBR PF01485.16 EMR69764.1 - 1e-22 79.7 44.7 3.4e-12 46.0 4.0 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 EMR69764.1 - 2.3e-06 27.5 7.1 2.3e-06 27.5 5.0 4.7 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMR69764.1 - 4e-06 26.3 42.7 0.00012 21.6 4.2 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMR69764.1 - 1e-05 25.2 43.6 0.00026 20.7 5.0 3.6 2 1 1 3 3 3 3 Ring finger domain zf-RING_5 PF14634.1 EMR69764.1 - 0.0043 16.7 8.7 0.0043 16.7 6.1 3.9 2 1 1 3 3 3 2 zinc-RING finger domain UN_NPL4 PF11543.3 EMR69764.1 - 0.048 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-rbx1 PF12678.2 EMR69764.1 - 0.056 13.5 28.7 0.086 12.9 3.2 3.5 2 1 1 3 3 3 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EMR69764.1 - 0.49 10.1 22.9 0.059 13.0 1.8 3.8 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EMR69764.1 - 0.75 9.7 34.1 0.18 11.7 2.2 4.6 3 2 0 3 3 3 0 zinc finger of C3HC4-type, RING Epimerase PF01370.16 EMR69766.1 - 2.9e-13 49.7 0.0 5e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR69766.1 - 2.6e-11 43.8 2.1 4.4e-11 43.1 1.4 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR69766.1 - 2.4e-05 23.7 0.0 6.3e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EMR69766.1 - 0.00039 20.3 0.8 0.0013 18.6 0.5 2.0 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EMR69766.1 - 0.00062 18.7 0.1 1.2 7.9 0.0 2.6 3 0 0 3 3 3 2 RmlD substrate binding domain 3Beta_HSD PF01073.14 EMR69766.1 - 0.0011 17.7 0.0 0.0017 17.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_16 PF00722.16 EMR69767.1 - 3.2e-08 33.0 0.0 4.2e-06 26.1 0.0 2.7 3 0 0 3 3 3 2 Glycosyl hydrolases family 16 DUF1467 PF07330.7 EMR69767.1 - 0.026 14.2 0.1 0.05 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) DUF605 PF04652.11 EMR69767.1 - 4.9 6.4 16.2 6.7 5.9 11.2 1.2 1 0 0 1 1 1 0 Vta1 like PAP2 PF01569.16 EMR69768.1 - 1.5e-19 69.9 5.3 4e-19 68.5 3.7 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 EMR69768.1 - 0.84 9.9 5.0 3.4 8.0 3.5 2.0 1 1 0 1 1 1 0 PAP2 superfamily C-terminal TPPK_C PF12555.3 EMR69768.1 - 2.7 7.7 6.6 18 5.1 1.6 2.9 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Polysacc_synt_C PF14667.1 EMR69768.1 - 4.2 7.1 11.7 0.88 9.3 2.9 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Aldose_epim PF01263.15 EMR69769.1 - 7.4e-56 189.4 0.0 1e-55 189.0 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase XPG_I PF00867.13 EMR69770.1 - 3.8e-25 87.7 0.0 7.3e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EMR69770.1 - 3.2e-24 85.1 0.0 6.1e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EMR69770.1 - 2.1e-05 24.1 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing TPR_11 PF13414.1 EMR69770.1 - 0.053 13.1 0.1 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 TPR repeat TPR_16 PF13432.1 EMR69770.1 - 0.12 13.1 0.1 0.2 12.3 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Redoxin PF08534.5 EMR69771.1 - 1.2e-25 89.7 0.0 1.6e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EMR69771.1 - 2.6e-08 33.5 0.0 3.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family RCC1 PF00415.13 EMR69772.1 - 3.1e-27 94.5 4.7 1.5e-05 25.0 0.0 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EMR69772.1 - 7.2e-14 50.9 17.8 4.4e-11 42.0 0.0 6.3 7 1 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Phospholip_A2_3 PF09056.6 EMR69773.1 - 5.6e-41 139.2 0.1 6.8e-41 138.9 0.1 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Glyco_hydro_11 PF00457.12 EMR69774.1 - 3.6e-79 264.3 20.2 4.2e-79 264.1 14.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 RHIM PF12721.2 EMR69774.1 - 0.16 12.4 5.9 1.3 9.4 0.4 3.6 2 1 1 3 3 3 0 RIP homotypic interaction motif adh_short PF00106.20 EMR69775.1 - 1.3e-18 67.4 2.6 1.5e-18 67.3 0.9 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR69775.1 - 7.8e-11 41.9 0.2 1.5e-10 41.0 0.1 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR69775.1 - 2.6e-05 24.1 0.1 3.6e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR69775.1 - 0.0049 16.3 0.0 0.0087 15.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR69775.1 - 0.026 14.5 0.1 0.081 12.9 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding CW_binding_2 PF04122.7 EMR69775.1 - 0.047 13.9 0.1 0.085 13.0 0.1 1.5 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 DUF2962 PF11176.3 EMR69777.1 - 6.5e-44 149.2 8.1 7.4e-44 149.0 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DUF3008 PF11450.3 EMR69777.1 - 0.032 14.3 0.2 4.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) ATP-synt_ab_C PF00306.22 EMR69777.1 - 0.036 14.5 2.1 0.057 13.9 1.5 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain UPF0270 PF06794.7 EMR69777.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0270) CBM_2 PF00553.14 EMR69777.1 - 0.21 11.6 0.7 0.31 11.0 0.5 1.2 1 0 0 1 1 1 0 Cellulose binding domain HTH_32 PF13565.1 EMR69777.1 - 7.2 7.4 8.7 8.7 7.2 0.3 2.9 1 1 2 3 3 3 0 Homeodomain-like domain Lipase_3 PF01764.20 EMR69778.1 - 2.4e-26 92.0 0.0 3.4e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Sec34 PF04136.10 EMR69779.1 - 2.6e-30 105.1 0.2 6.3e-30 103.9 0.1 1.6 1 0 0 1 1 1 1 Sec34-like family Pkinase PF00069.20 EMR69780.1 - 8.1e-11 41.5 0.0 3.5e-09 36.2 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR69780.1 - 2.8e-05 23.3 0.6 0.028 13.4 0.2 3.7 3 1 0 3 3 3 2 Protein tyrosine kinase DNA_ligase_A_M PF01068.16 EMR69781.1 - 2.2e-48 164.3 0.1 6.1e-46 156.3 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EMR69781.1 - 4.5e-41 140.5 0.0 9.5e-41 139.5 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EMR69781.1 - 4e-18 65.6 0.0 7.8e-10 39.0 0.0 3.2 3 0 0 3 3 3 2 ATP dependent DNA ligase C terminal region DUF1118 PF06549.7 EMR69781.1 - 0.15 12.1 0.1 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) Arylsulfotran_2 PF14269.1 EMR69782.1 - 7.3e-69 232.1 0.3 1.2e-68 231.4 0.2 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EMR69782.1 - 1.7e-15 56.5 0.3 1.4e-14 53.5 0.1 2.4 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) MFS_1 PF07690.11 EMR69783.1 - 1.4e-38 132.4 43.9 5.1e-38 130.6 29.0 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR69783.1 - 1.5e-14 53.4 1.2 1.5e-14 53.4 0.8 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter HSP70 PF00012.15 EMR69784.1 - 2.5e-78 263.5 0.0 3.9e-78 262.8 0.0 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EMR69784.1 - 0.00016 20.3 0.2 0.01 14.4 0.1 2.8 3 0 0 3 3 3 1 MreB/Mbl protein Lipase3_N PF03893.11 EMR69786.1 - 0.069 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipase 3 N-terminal region Fungal_trans_2 PF11951.3 EMR69787.1 - 0.0012 17.4 0.0 0.0021 16.7 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4243 PF14027.1 EMR69787.1 - 0.018 14.4 0.1 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4243) Asp PF00026.18 EMR69788.1 - 1.7e-34 119.5 0.0 2.3e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMR69788.1 - 0.025 14.5 0.0 0.07 13.0 0.0 1.8 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal DUF2668 PF10873.3 EMR69788.1 - 0.034 14.3 0.1 0.07 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) RTA1 PF04479.8 EMR69789.1 - 1.6e-50 171.6 4.5 2e-50 171.3 3.1 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF2207 PF09972.4 EMR69789.1 - 0.093 11.2 0.6 0.98 7.9 0.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Glyco_hydro_43 PF04616.9 EMR69790.1 - 1.2e-42 146.0 0.0 6e-42 143.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 LSM PF01423.17 EMR69792.1 - 0.00072 19.0 0.0 0.0059 16.1 0.0 2.0 1 1 0 1 1 1 1 LSM domain GlutR_dimer PF00745.15 EMR69792.1 - 0.11 12.3 1.1 6.9 6.6 0.1 2.4 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Response_reg PF00072.19 EMR69793.1 - 1.5e-20 73.3 0.2 3.1e-20 72.2 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EMR69793.1 - 7.3e-15 54.6 0.0 1.5e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.19 EMR69793.1 - 7e-11 41.9 0.1 2.3e-09 37.0 0.0 3.3 4 0 0 4 4 4 1 PAS fold PAS_9 PF13426.1 EMR69793.1 - 3.9e-09 36.8 0.0 4.3e-07 30.2 0.0 2.7 2 0 0 2 2 2 1 PAS domain HisKA PF00512.20 EMR69793.1 - 6.2e-08 32.5 0.2 6.2e-08 32.5 0.2 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 EMR69793.1 - 8.1e-06 26.3 0.0 0.0056 17.1 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 EMR69793.1 - 4.2e-05 23.6 0.0 0.0012 18.9 0.0 2.5 2 0 0 2 2 2 1 GAF domain PAS_4 PF08448.5 EMR69793.1 - 6.9e-05 22.8 0.0 0.019 15.0 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.6 EMR69793.1 - 0.0022 18.0 0.4 0.0048 16.9 0.3 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 EMR69793.1 - 0.0035 17.1 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 PAS domain XPG_N PF00752.12 EMR69795.1 - 9.9e-34 115.6 0.0 2e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EMR69795.1 - 8.1e-25 86.7 0.0 2.5e-24 85.1 0.0 1.9 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 EMR69795.1 - 0.021 14.3 0.2 0.021 14.3 0.1 3.4 3 0 0 3 3 3 0 Ubiquitin interaction motif Glutaredoxin PF00462.19 EMR69796.1 - 9.6e-22 76.7 0.0 1.5e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DSBA PF01323.15 EMR69796.1 - 0.0097 15.4 0.1 0.084 12.4 0.0 1.9 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 EMR69796.1 - 0.016 15.4 0.1 0.021 15.0 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 EMR69796.1 - 0.029 14.6 0.0 0.04 14.1 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 EMR69796.1 - 0.047 13.4 0.1 0.1 12.4 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin domain p450 PF00067.17 EMR69797.1 - 1.9e-55 188.2 0.0 2.5e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_11 PF13414.1 EMR69798.1 - 2.1e-10 40.1 5.1 2.7e-07 30.1 0.9 3.9 3 1 1 4 4 4 1 TPR repeat TPR_19 PF14559.1 EMR69798.1 - 6.9e-08 32.7 1.3 2.1e-05 24.7 0.2 3.7 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMR69798.1 - 2.8e-07 29.8 1.1 3.1e-05 23.3 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMR69798.1 - 4.8e-07 30.2 6.9 2.8e-05 24.6 0.5 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMR69798.1 - 1.5e-06 28.3 3.9 0.00054 20.3 0.6 4.7 3 1 4 7 7 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMR69798.1 - 1.7e-06 27.4 3.9 5.8e-05 22.7 0.4 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMR69798.1 - 7.2e-06 25.8 0.2 0.067 13.4 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMR69798.1 - 3.8e-05 23.1 0.1 0.0026 17.3 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMR69798.1 - 0.0013 18.5 5.9 0.025 14.4 0.2 3.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMR69798.1 - 0.0057 16.4 0.2 0.024 14.4 0.1 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EMR69798.1 - 0.013 15.6 0.0 0.048 13.8 0.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EMR69798.1 - 0.014 15.1 0.2 0.2 11.5 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 EMR69798.1 - 0.016 15.3 1.6 0.37 10.9 0.3 3.0 3 1 1 4 4 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMR69798.1 - 0.05 14.0 3.7 1.3 9.6 0.1 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat FAT PF02259.18 EMR69798.1 - 0.085 11.8 0.0 4.4 6.1 0.0 2.1 1 1 1 2 2 2 0 FAT domain Methyltransf_12 PF08242.7 EMR69799.1 - 5.2e-17 62.1 0.1 3.2e-16 59.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR69799.1 - 3.3e-15 56.3 0.0 6.9e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR69799.1 - 5.6e-14 52.3 0.0 1.3e-13 51.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR69799.1 - 9.8e-13 48.1 0.0 1.6e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR69799.1 - 4.2e-12 45.9 0.0 9.9e-12 44.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR69799.1 - 1.9e-10 40.2 0.0 2.8e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EMR69799.1 - 7.2e-10 39.4 0.0 1.5e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR69799.1 - 5.1e-07 29.7 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR69799.1 - 6.7e-06 25.5 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 EMR69799.1 - 0.00048 20.9 0.0 0.0015 19.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain DUF3419 PF11899.3 EMR69799.1 - 0.0011 17.7 0.0 0.0017 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) NNMT_PNMT_TEMT PF01234.12 EMR69799.1 - 0.0012 17.9 0.0 0.26 10.2 0.0 2.3 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.10 EMR69799.1 - 0.0012 18.4 0.0 0.0033 17.0 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_16 PF10294.4 EMR69799.1 - 0.0017 17.8 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EMR69799.1 - 0.006 15.6 0.1 0.012 14.6 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 EMR69799.1 - 0.0097 15.0 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB FmrO PF07091.6 EMR69799.1 - 0.054 12.4 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 EMR69799.1 - 0.057 13.0 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Frag1 PF10277.4 EMR69800.1 - 1.6e-38 132.3 19.7 1.8e-38 132.1 13.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MreD PF04093.7 EMR69800.1 - 2.7 7.8 15.3 0.13 12.0 5.3 2.5 2 1 1 3 3 3 0 rod shape-determining protein MreD DUF4184 PF13803.1 EMR69800.1 - 2.9 7.1 12.2 0.14 11.5 2.4 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4184) PAP2_C PF14360.1 EMR69800.1 - 4.3 7.6 10.2 13 6.1 1.8 3.0 2 1 1 3 3 3 0 PAP2 superfamily C-terminal ABC2_membrane_3 PF12698.2 EMR69800.1 - 8 5.3 21.2 23 3.8 14.7 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein Chalcone PF02431.10 EMR69801.1 - 1.5e-55 187.6 0.0 1.9e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Y_phosphatase3 PF13350.1 EMR69803.1 - 7.3e-32 110.8 0.3 1.1e-15 58.2 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EMR69803.1 - 6.8e-05 22.2 0.0 0.00034 20.0 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EMR69803.1 - 0.0034 17.4 0.3 0.026 14.6 0.0 2.4 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EMR69803.1 - 0.0064 15.8 0.0 0.0095 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EMR69803.1 - 0.0069 15.9 0.0 0.28 10.7 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EMR69803.1 - 0.018 13.8 0.2 0.032 12.9 0.0 1.4 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain Glyco_hyd_65N_2 PF14498.1 EMR69804.1 - 3.6e-08 33.3 0.0 6.9e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.10 EMR69804.1 - 0.019 13.6 0.2 0.057 12.1 0.1 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 65 central catalytic domain RHS_repeat PF05593.9 EMR69804.1 - 0.15 12.2 0.7 12 6.2 0.1 3.0 3 0 0 3 3 3 0 RHS Repeat Ribosomal_L13 PF00572.13 EMR69805.1 - 2.8e-27 95.3 0.0 4.9e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 p450 PF00067.17 EMR69806.1 - 4.9e-43 147.3 0.0 7.3e-22 77.5 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 EF-hand_8 PF13833.1 EMR69807.1 - 0.0035 16.9 0.0 0.014 14.9 0.0 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 EMR69807.1 - 0.051 13.7 0.0 0.35 11.0 0.0 2.4 4 0 0 4 4 4 0 EF-hand domain pair IGR PF09597.5 EMR69808.1 - 4.8e-23 80.8 0.0 8.5e-23 80.0 0.0 1.4 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.25 EMR69808.1 - 0.0012 18.9 0.0 0.0021 18.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Polyketide_cyc PF03364.15 EMR69809.1 - 1.1e-23 83.5 0.1 5.1e-23 81.4 0.1 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EMR69809.1 - 0.00036 20.7 2.8 0.1 12.8 0.2 2.6 1 1 1 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport bZIP_2 PF07716.10 EMR69810.1 - 0.033 14.0 11.5 0.033 14.0 8.0 2.1 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.16 EMR69810.1 - 0.044 13.7 10.1 0.044 13.7 7.0 1.7 2 0 0 2 2 2 0 bZIP transcription factor Med15 PF09606.5 EMR69810.1 - 1.5 6.9 15.4 1.7 6.7 10.7 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MMR1 PF08505.5 EMR69810.1 - 1.9 8.4 9.2 0.37 10.8 1.5 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein bZIP_Maf PF03131.12 EMR69810.1 - 8.3 6.7 21.0 1 9.7 5.7 2.4 2 0 0 2 2 2 0 bZIP Maf transcription factor Pkinase PF00069.20 EMR69811.1 - 1.9e-65 220.6 0.0 2.3e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR69811.1 - 1.4e-35 122.5 0.0 2.2e-35 121.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR69811.1 - 0.0015 17.5 0.0 0.0037 16.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like DUF3812 PF12757.2 EMR69812.1 - 4.5e-34 117.1 12.7 4.5e-34 117.1 8.8 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF3812) YjgP_YjgQ PF03739.9 EMR69813.1 - 0.00092 18.0 2.4 0.0011 17.8 1.6 1.1 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family Helicase_C PF00271.26 EMR69814.1 - 0.025 14.4 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain BAG PF02179.11 EMR69815.1 - 6.1e-20 71.1 0.1 1.3e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EMR69815.1 - 0.0012 18.1 0.0 0.003 16.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family FLO_LFY PF01698.11 EMR69815.1 - 0.11 11.2 3.9 0.14 10.9 2.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF89 PF01937.14 EMR69817.1 - 9.8e-128 425.8 0.0 1.2e-127 425.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Peptidase_S8 PF00082.17 EMR69818.1 - 9.1e-49 166.1 0.6 1.3e-48 165.5 0.4 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMR69818.1 - 6.2e-07 29.8 0.1 1.2e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1843 PF08898.5 EMR69819.1 - 0.39 10.8 2.7 0.99 9.4 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) GEMIN8 PF15348.1 EMR69819.1 - 6.8 6.6 8.9 0.28 11.2 0.8 2.0 1 1 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Glyco_hydro_61 PF03443.9 EMR69820.1 - 0.0043 16.8 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 E1_DerP2_DerF2 PF02221.10 EMR69821.1 - 3.9e-24 85.4 0.3 4.7e-24 85.1 0.2 1.1 1 0 0 1 1 1 1 ML domain CopC PF04234.7 EMR69821.1 - 0.0039 17.7 0.0 0.0064 17.0 0.0 1.4 1 0 0 1 1 1 1 CopC domain TRP_N PF14558.1 EMR69821.1 - 0.0066 16.4 0.3 0.043 13.8 0.1 2.1 1 1 0 1 1 1 1 ML-like domain DUF221 PF02714.10 EMR69822.1 - 1.2e-104 349.7 27.2 1.2e-104 349.7 18.9 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EMR69822.1 - 8.4e-46 155.3 2.6 8.4e-46 155.3 1.8 3.2 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EMR69822.1 - 2.4e-30 104.2 0.2 7.9e-30 102.5 0.1 1.9 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EMR69822.1 - 5e-21 75.0 0.2 8.2e-21 74.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) GED PF02212.13 EMR69822.1 - 0.049 13.5 1.1 12 5.9 0.4 2.9 3 0 0 3 3 3 0 Dynamin GTPase effector domain DUF2418 PF10332.4 EMR69824.1 - 5.2e-34 116.5 0.6 1e-33 115.5 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.12 EMR69825.1 - 2.1e-33 114.5 0.2 2.4e-33 114.3 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Jag_N PF14804.1 EMR69825.1 - 0.05 13.6 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 Jag N-terminus NPV_P10 PF05531.7 EMR69826.1 - 0.32 11.2 2.8 2.1 8.6 0.1 2.7 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein p450 PF00067.17 EMR69827.1 - 5.2e-63 213.1 0.0 6.7e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 EMR69828.1 - 5e-06 25.3 0.0 2.2e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain NmrA PF05368.8 EMR69829.1 - 1.2e-61 207.9 0.0 1.5e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR69829.1 - 6.5e-15 55.6 0.0 8.6e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMR69829.1 - 0.0043 15.8 0.0 0.0062 15.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CBM-like PF14683.1 EMR69832.1 - 2e-10 40.5 0.0 3.4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EMR69832.1 - 7.8e-07 29.1 0.0 2.2e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II Cupin_2 PF07883.6 EMR69833.1 - 2.3e-08 33.4 0.5 9.5e-07 28.2 0.0 2.1 1 1 1 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EMR69833.1 - 0.016 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF1255 PF06865.6 EMR69833.1 - 0.066 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1255) DSPc PF00782.15 EMR69835.1 - 5.7e-11 42.1 0.0 1.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMR69835.1 - 0.00016 21.1 0.2 0.00046 19.6 0.1 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMR69835.1 - 0.001 19.3 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EMR69835.1 - 0.011 15.7 0.0 0.039 14.0 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.7 EMR69835.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) UPF0121 PF03661.8 EMR69836.1 - 1.9e-11 43.6 0.3 2.7e-11 43.1 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Phage_holin_3 PF05106.7 EMR69836.1 - 0.015 15.2 1.7 0.073 13.0 0.2 2.2 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) YGGT PF02325.12 EMR69836.1 - 1.5 8.7 5.5 0.83 9.6 0.4 2.8 2 1 2 4 4 4 0 YGGT family La PF05383.12 EMR69837.1 - 2.9e-15 55.8 0.0 4.4e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EMR69837.1 - 5.3e-07 29.1 0.4 1.8e-06 27.4 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR69837.1 - 7.9e-07 28.9 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR69837.1 - 0.003 17.3 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 EMR69838.1 - 6.2e-42 143.5 15.0 6.2e-42 143.5 10.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR69838.1 - 3.3e-13 49.0 6.7 6.8e-13 47.9 4.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EMR69838.1 - 0.021 12.8 0.5 0.24 9.4 1.0 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.13 EMR69839.1 - 3.7e-43 147.2 0.2 4.6e-43 146.9 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Swi3 PF07962.7 EMR69839.1 - 0.22 11.2 0.7 4.6 6.9 0.1 2.4 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 LSM PF01423.17 EMR69840.1 - 2.6e-15 55.6 0.0 4.7e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 LSM domain Pox_I1 PF03289.8 EMR69840.1 - 0.065 12.0 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus protein I1 SAP18 PF06487.7 EMR69840.1 - 0.14 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) PPR_2 PF13041.1 EMR69842.1 - 4e-10 39.5 0.1 0.11 12.5 0.0 6.1 6 2 2 8 8 8 5 PPR repeat family PPR PF01535.15 EMR69842.1 - 1.9e-09 36.8 0.0 17 5.6 0.0 7.7 8 0 0 8 8 8 3 PPR repeat PPR_3 PF13812.1 EMR69842.1 - 2.4e-09 36.7 2.4 0.062 13.6 0.0 7.3 9 0 0 9 9 9 2 Pentatricopeptide repeat domain ALAD PF00490.16 EMR69842.1 - 0.058 12.2 0.2 0.3 9.9 0.0 1.9 2 0 0 2 2 2 0 Delta-aminolevulinic acid dehydratase Septin PF00735.13 EMR69843.1 - 3.6e-122 406.7 0.2 3.6e-122 406.7 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EMR69843.1 - 2.4e-07 30.7 0.0 5.1e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EMR69843.1 - 7.8e-05 21.9 0.4 0.00068 18.8 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EMR69843.1 - 0.0001 22.5 0.9 0.023 14.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.22 EMR69843.1 - 0.00016 21.1 0.3 0.0049 16.3 0.0 2.9 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EMR69843.1 - 0.00031 20.2 0.0 0.0014 18.1 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EMR69843.1 - 0.0024 17.8 0.1 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.11 EMR69843.1 - 0.0031 16.6 1.6 0.0072 15.4 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 EMR69843.1 - 0.0043 17.5 0.0 0.016 15.6 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EMR69843.1 - 0.0055 16.8 0.1 0.033 14.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain Ras PF00071.17 EMR69843.1 - 0.0062 15.9 0.3 0.054 12.8 0.0 2.5 3 0 0 3 3 3 1 Ras family FtsK_SpoIIIE PF01580.13 EMR69843.1 - 0.0066 15.9 0.0 0.027 13.9 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.1 EMR69843.1 - 0.0094 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 EMR69843.1 - 0.043 13.6 7.2 0.71 9.6 0.0 3.6 4 1 0 4 4 4 0 Dynamin family RNA_helicase PF00910.17 EMR69843.1 - 0.078 13.1 0.6 0.64 10.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 EMR69843.1 - 0.08 12.5 0.6 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EMR69843.1 - 0.15 11.7 1.7 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Exonuc_VII_L PF02601.10 EMR69843.1 - 0.19 10.8 6.1 0.32 10.1 4.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Strep_SA_rep PF06696.6 EMR69843.1 - 0.19 11.5 2.9 0.25 11.1 0.9 2.0 1 1 1 2 2 2 0 Streptococcal surface antigen repeat AAA_32 PF13654.1 EMR69843.1 - 0.58 8.7 12.5 0.53 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 EMR69843.1 - 1.4 8.4 8.4 2.2 7.8 5.8 1.3 1 0 0 1 1 1 0 IncA protein Phage_GPO PF05929.6 EMR69843.1 - 2 7.5 7.0 3.1 6.9 4.9 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase V_ATPase_I PF01496.14 EMR69843.1 - 2 6.1 8.5 3.5 5.3 5.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fe-ADH PF00465.14 EMR69844.1 - 7.6e-61 205.7 0.3 9.4e-61 205.4 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EMR69844.1 - 3.9e-10 39.4 0.9 9.4e-05 21.8 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase S4 PF01479.20 EMR69846.1 - 2.5e-16 58.8 1.1 1.1e-12 47.1 0.3 3.3 3 0 0 3 3 3 2 S4 domain SR-25 PF10500.4 EMR69846.1 - 0.0044 16.5 3.5 0.0044 16.5 2.4 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein PLRV_ORF5 PF01690.12 EMR69846.1 - 0.57 9.2 10.6 0.81 8.7 7.3 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein zf-rbx1 PF12678.2 EMR69847.1 - 4.3e-35 119.6 13.5 5.4e-35 119.3 9.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EMR69847.1 - 4.3e-17 61.7 9.8 5.6e-17 61.3 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EMR69847.1 - 4.6e-07 29.5 11.6 3e-06 26.9 8.0 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMR69847.1 - 0.0013 18.3 11.3 0.022 14.4 7.8 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMR69847.1 - 0.0032 17.1 9.5 0.35 10.5 6.8 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMR69847.1 - 0.051 13.6 12.5 0.055 13.4 5.4 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR69847.1 - 0.55 10.0 11.7 5.2 6.8 8.1 2.4 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.3 EMR69847.1 - 0.88 9.5 9.3 4.9 7.2 6.6 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 EMR69847.1 - 1.7 8.8 10.6 1.2e+02 2.9 7.4 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 EMR69847.1 - 2 8.2 7.0 45 3.8 4.9 2.2 1 1 0 1 1 1 0 RING-type zinc-finger ELFV_dehydrog PF00208.16 EMR69848.1 - 8.6e-58 195.7 0.0 1.4e-57 195.0 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EMR69848.1 - 1.4e-21 75.7 0.0 8.1e-17 60.0 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EMR69848.1 - 0.0031 17.0 0.0 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Tyr-DNA_phospho PF06087.7 EMR69849.1 - 4.5e-08 32.1 0.0 6e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.15 EMR69849.1 - 0.0051 16.2 2.9 0.011 15.2 0.2 2.7 2 0 0 2 2 2 1 Ubiquitin interaction motif CorA PF01544.13 EMR69850.1 - 8.6e-41 139.8 0.0 1.1e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_M50B PF13398.1 EMR69851.1 - 0.0046 16.3 0.6 0.0046 16.3 0.4 1.6 2 0 0 2 2 2 1 Peptidase M50B-like DUF2189 PF09955.4 EMR69851.1 - 0.0072 16.2 1.0 0.0072 16.2 0.7 1.8 1 1 0 2 2 2 1 Predicted integral membrane protein (DUF2189) LRRC37AB_C PF14914.1 EMR69851.1 - 0.012 15.0 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF3169 PF11368.3 EMR69851.1 - 0.017 14.3 0.9 0.021 14.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) AgrB PF04647.10 EMR69851.1 - 0.021 13.8 1.2 0.033 13.2 0.9 1.4 1 0 0 1 1 1 0 Accessory gene regulator B UPF0182 PF03699.8 EMR69851.1 - 0.036 12.0 1.2 0.036 12.0 0.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Yip1 PF04893.12 EMR69851.1 - 0.06 12.8 4.1 0.11 11.9 2.8 1.4 1 1 0 1 1 1 0 Yip1 domain DUF3087 PF11286.3 EMR69851.1 - 0.12 11.6 0.4 0.29 10.3 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3087) FeoB_C PF07664.7 EMR69851.1 - 0.27 10.7 0.1 0.27 10.7 0.0 2.4 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus DUF4131 PF13567.1 EMR69851.1 - 0.27 10.6 4.3 0.68 9.3 3.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) IBV_3C PF03620.8 EMR69851.1 - 0.56 10.1 4.5 4.2 7.3 1.5 2.2 1 1 1 2 2 2 0 IBV 3C protein SUR7 PF06687.7 EMR69851.1 - 0.6 9.6 10.4 0.048 13.2 3.0 1.8 1 1 1 2 2 2 0 SUR7/PalI family DUF4234 PF14018.1 EMR69851.1 - 1.1 9.0 6.8 2 8.2 4.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) PRA1 PF03208.14 EMR69851.1 - 1.6 8.0 6.4 0.22 10.8 1.0 1.8 2 0 0 2 2 2 0 PRA1 family protein DUF3270 PF11674.3 EMR69851.1 - 2.4 8.2 5.1 1.6 8.8 1.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3270) Dynamin_N PF00350.18 EMR69852.1 - 6.7e-29 100.8 0.0 1.5e-28 99.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EMR69852.1 - 2.6e-21 75.6 0.6 2.8e-18 65.7 0.0 3.3 1 1 1 3 3 3 1 Dynamin central region GED PF02212.13 EMR69852.1 - 0.00031 20.5 0.3 0.0021 17.9 0.0 2.6 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EMR69852.1 - 0.0072 16.2 0.0 0.049 13.5 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMR69852.1 - 0.011 16.2 0.0 0.039 14.4 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein HET PF06985.6 EMR69853.1 - 4e-22 78.8 0.4 1e-21 77.5 0.3 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Med12-PQL PF12144.3 EMR69854.1 - 0.065 12.5 0.1 0.2 11.0 0.1 1.7 2 1 0 2 2 2 0 Eukaryotic Mediator 12 catenin-binding domain Fungal_trans_2 PF11951.3 EMR69855.1 - 1.9e-08 33.3 0.8 1.1e-07 30.8 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain CDP-OH_P_transf PF01066.16 EMR69856.1 - 4.6e-10 39.6 0.4 4.6e-10 39.6 0.3 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Na_Pi_cotrans PF02690.10 EMR69856.1 - 0.15 11.7 2.7 0.17 11.6 0.2 1.9 1 1 0 2 2 2 0 Na+/Pi-cotransporter Proteasome PF00227.21 EMR69857.1 - 2.9e-56 189.7 0.2 4.2e-56 189.2 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMR69857.1 - 1.8e-12 46.3 0.1 1.8e-12 46.3 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature zf-CHY PF05495.7 EMR69858.1 - 3.5e-14 52.7 20.6 4.4e-14 52.3 14.3 1.1 1 0 0 1 1 1 1 CHY zinc finger PAZ_siRNAbind PF12212.3 EMR69858.1 - 0.07 12.7 0.2 9.9 5.8 0.0 3.1 3 0 0 3 3 3 0 Piwi/Argonaute/Zwille siRNA-binding domain Cytochrome_C7 PF14522.1 EMR69858.1 - 0.57 9.8 13.9 0.88 9.2 9.7 1.3 1 0 0 1 1 1 0 Cytochrome c7 DUF3797 PF12677.2 EMR69858.1 - 0.76 9.4 0.0 0.76 9.4 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) Evr1_Alr PF04777.8 EMR69858.1 - 2.8 7.9 13.4 30 4.6 9.3 2.6 1 1 0 1 1 1 0 Erv1 / Alr family HypA PF01155.14 EMR69858.1 - 6.7 6.4 12.8 58 3.4 8.9 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family RNA_POL_M_15KD PF02150.11 EMR69858.1 - 7.9 6.2 12.4 14 5.4 0.0 3.4 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit SPC12 PF06645.8 EMR69859.1 - 9e-28 95.9 0.1 1e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) UCR_Fe-S_N PF10399.4 EMR69859.1 - 4.5 6.5 6.2 0.31 10.2 0.7 1.8 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Ribosomal_S13 PF00416.17 EMR69860.1 - 2.5e-19 69.7 0.1 2.8e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 N-SET PF11764.3 EMR69861.1 - 1.2e-40 139.1 0.8 1.2e-40 139.1 0.6 2.2 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 EMR69861.1 - 4.3e-24 85.6 0.3 4.3e-24 85.6 0.2 3.2 2 2 0 2 2 2 1 SET domain SET_assoc PF11767.3 EMR69861.1 - 9.8e-16 56.8 0.1 2.9e-15 55.3 0.1 1.8 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated RRM_1 PF00076.17 EMR69861.1 - 0.0046 16.5 0.1 1.4 8.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.21 EMR69862.1 - 1.1e-35 122.6 0.0 1.5e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit DUF2633 PF11119.3 EMR69864.1 - 0.04 13.6 0.1 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) DUF1510 PF07423.6 EMR69864.1 - 0.042 13.2 14.6 0.061 12.6 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAPS PF04499.10 EMR69864.1 - 0.088 11.4 3.0 0.1 11.2 2.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ABC2_membrane_3 PF12698.2 EMR69864.1 - 0.11 11.5 2.0 0.15 11.0 1.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Macoilin PF09726.4 EMR69864.1 - 0.23 9.7 4.4 0.28 9.4 3.0 1.3 1 0 0 1 1 1 0 Transmembrane protein Tim54 PF11711.3 EMR69864.1 - 0.31 9.6 5.8 0.48 8.9 4.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SID-1_RNA_chan PF13965.1 EMR69864.1 - 0.51 8.4 2.2 0.73 7.9 1.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 BUD22 PF09073.5 EMR69864.1 - 1.3 8.0 11.0 1.9 7.4 7.6 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EMR69864.1 - 2.1 6.1 13.6 2.8 5.7 9.4 1.0 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 EMR69864.1 - 4.2 4.9 8.3 5.7 4.4 5.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ATP-synt_S1 PF05827.7 EMR69865.1 - 3.5e-34 118.4 3.7 1.5e-33 116.3 2.5 1.8 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) HTH_Tnp_1 PF01527.15 EMR69865.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Transposase Nop25 PF09805.4 EMR69866.1 - 5.4e-37 126.9 12.9 5.4e-37 126.9 8.9 3.0 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) Med15_fungi PF05397.7 EMR69866.1 - 0.065 13.2 4.1 0.12 12.3 2.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 15 Nop53 PF07767.6 EMR69866.1 - 4 6.3 36.3 0.11 11.4 11.7 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Pal1 PF08316.6 EMR69866.1 - 5.8 7.3 9.0 18 5.7 0.2 2.1 2 0 0 2 2 2 0 Pal1 cell morphology protein DEAD PF00270.24 EMR69867.1 - 4.6e-46 156.3 0.0 1e-44 151.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR69867.1 - 3.4e-28 97.3 0.1 7.1e-28 96.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR69867.1 - 0.019 14.7 0.0 0.053 13.3 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 EMR69867.1 - 0.038 13.0 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EMR69867.1 - 0.094 11.0 0.0 0.19 10.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) FCH PF00611.18 EMR69868.1 - 2.5e-17 62.8 0.2 1.5e-16 60.3 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 EMR69868.1 - 7.3e-16 58.1 1.1 5.2e-15 55.3 0.1 2.4 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.16 EMR69868.1 - 1.1e-12 47.5 0.0 2.4e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Med4 PF10018.4 EMR69868.1 - 0.0062 15.9 0.2 0.0062 15.9 0.2 2.6 3 0 0 3 3 3 1 Vitamin-D-receptor interacting Mediator subunit 4 ArdA PF07275.6 EMR69868.1 - 0.12 12.5 0.8 0.27 11.4 0.6 1.5 1 0 0 1 1 1 0 Antirestriction protein (ArdA) ABC_membrane PF00664.18 EMR69869.1 - 3e-48 164.6 36.4 4.4e-25 88.6 13.4 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EMR69869.1 - 5e-46 156.4 0.1 1.3e-25 90.2 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_16 PF13191.1 EMR69869.1 - 9.2e-06 25.7 0.4 0.08 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EMR69869.1 - 5.9e-05 23.5 2.0 0.089 13.2 0.1 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_21 PF13304.1 EMR69869.1 - 7.8e-05 22.7 0.2 1.4 8.8 0.0 4.0 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 EMR69869.1 - 0.00016 20.7 0.0 0.04 12.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.18 EMR69869.1 - 0.00028 20.8 0.7 0.21 11.5 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EMR69869.1 - 0.00064 19.1 0.6 1.3 8.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 EMR69869.1 - 0.00065 19.5 1.4 0.11 12.3 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_25 PF13481.1 EMR69869.1 - 0.00072 19.0 0.0 0.17 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EMR69869.1 - 0.0014 17.9 0.4 5.9 6.0 0.1 3.4 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMR69869.1 - 0.0016 18.8 0.8 1.7 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMR69869.1 - 0.0018 17.5 1.2 0.67 9.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMR69869.1 - 0.0018 19.1 1.3 3.6 8.4 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EMR69869.1 - 0.0019 17.7 0.1 1.8 7.9 0.0 2.7 2 0 0 2 2 2 2 AAA-like domain ArgK PF03308.11 EMR69869.1 - 0.0037 16.0 0.9 1.6 7.4 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 EMR69869.1 - 0.0044 17.1 0.2 2.9 8.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EMR69869.1 - 0.0077 15.9 0.9 1.1 8.9 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EMR69869.1 - 0.016 14.7 5.6 1.2 8.6 0.1 3.0 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 EMR69869.1 - 0.033 13.6 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.17 EMR69869.1 - 0.042 13.2 0.1 0.65 9.3 0.0 2.6 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 EMR69869.1 - 0.052 13.0 0.0 6.6 6.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EMR69869.1 - 0.073 12.7 0.1 0.69 9.5 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase TrwB_AAD_bind PF10412.4 EMR69869.1 - 0.088 11.4 4.5 0.74 8.3 0.1 2.8 2 1 1 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 EMR69869.1 - 0.092 12.4 3.1 0.15 11.7 0.0 2.5 3 0 0 3 3 2 0 NACHT domain RNA_helicase PF00910.17 EMR69869.1 - 0.18 11.9 0.2 30 4.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 EMR69869.1 - 0.19 11.5 4.6 1.1 9.0 0.5 2.8 2 0 0 2 2 2 0 Dynamin family cobW PF02492.14 EMR69869.1 - 0.2 11.0 2.7 0.41 10.0 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 EMR69869.1 - 0.31 10.2 0.2 9.2 5.4 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.12 EMR69869.1 - 0.9 9.0 5.5 8.1 5.8 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Tropomyosin_1 PF12718.2 EMR69870.1 - 6.7e-48 162.1 32.3 8.6e-48 161.8 22.4 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EMR69870.1 - 3e-08 33.0 30.3 7.9e-06 25.1 13.6 2.7 1 1 1 2 2 2 2 Tropomyosin Myosin_tail_1 PF01576.14 EMR69870.1 - 3.4e-05 21.8 31.6 4e-05 21.5 21.9 1.0 1 0 0 1 1 1 1 Myosin tail ATG16 PF08614.6 EMR69870.1 - 0.0001 22.2 30.2 0.014 15.1 6.4 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) IncA PF04156.9 EMR69870.1 - 0.0014 18.2 31.5 0.95 9.0 21.8 2.2 1 1 0 1 1 1 1 IncA protein ERM PF00769.14 EMR69870.1 - 0.0028 17.2 33.6 0.0098 15.4 11.4 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.3 EMR69870.1 - 0.0033 17.1 34.2 0.038 13.7 9.2 3.2 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 EMR69870.1 - 0.0056 16.8 9.7 0.057 13.6 0.2 3.1 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 EMR69870.1 - 0.0062 16.3 5.7 0.0062 16.3 4.0 2.5 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 EMR69870.1 - 0.01 15.7 31.3 0.085 12.7 10.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 EMR69870.1 - 0.012 14.8 3.4 0.093 11.8 0.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 EMR69870.1 - 0.013 15.4 32.8 0.28 11.1 0.9 5.4 1 1 5 6 6 6 0 bZIP transcription factor APG6 PF04111.7 EMR69870.1 - 0.013 14.5 33.2 0.076 12.0 12.0 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Vps5 PF09325.5 EMR69870.1 - 0.014 14.6 8.0 0.014 14.6 5.5 2.4 1 1 1 3 3 3 0 Vps5 C terminal like DUF869 PF05911.6 EMR69870.1 - 0.017 13.4 25.2 0.28 9.3 6.1 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) GAS PF13851.1 EMR69870.1 - 0.025 13.7 30.6 0.11 11.7 21.2 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EMR69870.1 - 0.03 14.2 31.2 0.17 11.8 6.3 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.7 EMR69870.1 - 0.04 13.6 15.5 0.017 14.9 3.9 2.2 1 1 1 2 2 2 0 Laminin Domain II Mod_r PF07200.8 EMR69870.1 - 0.043 13.7 25.5 0.73 9.7 10.9 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4482 PF14818.1 EMR69870.1 - 0.045 14.4 4.2 0.045 14.4 2.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) TBPIP PF07106.8 EMR69870.1 - 0.056 12.9 27.0 0.27 10.7 2.8 3.1 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Lebercilin PF15619.1 EMR69870.1 - 0.06 12.7 32.4 0.35 10.2 13.5 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CCDC155 PF14662.1 EMR69870.1 - 0.085 12.4 32.6 0.99 8.9 9.5 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 PilJ PF13675.1 EMR69870.1 - 0.096 13.0 11.4 1.1 9.6 3.7 2.7 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Herpes_pp85 PF04637.7 EMR69870.1 - 0.11 10.8 3.4 0.097 10.9 1.7 1.3 1 1 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF3287 PF11690.3 EMR69870.1 - 0.11 12.5 0.6 0.11 12.5 0.4 2.9 1 1 3 4 4 3 0 Protein of unknown function (DUF3287) Imm15 PF15590.1 EMR69870.1 - 0.12 11.5 1.4 0.23 10.5 0.2 2.0 2 0 0 2 2 2 0 Immunity protein 15 BLOC1_2 PF10046.4 EMR69870.1 - 0.12 12.5 21.5 0.65 10.1 1.0 3.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.6 EMR69870.1 - 0.14 10.7 26.9 0.017 13.7 10.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein CDC37_N PF03234.9 EMR69870.1 - 0.16 12.2 21.0 0.51 10.6 14.6 1.7 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding KAR9 PF08580.5 EMR69870.1 - 0.17 10.1 12.5 0.025 12.8 0.9 2.0 1 1 1 2 2 2 0 Yeast cortical protein KAR9 DUF904 PF06005.7 EMR69870.1 - 0.18 12.1 38.0 4.4 7.6 7.6 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF904) DUF2353 PF09789.4 EMR69870.1 - 0.18 11.0 24.0 0.33 10.1 16.7 1.5 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) EzrA PF06160.7 EMR69870.1 - 0.29 9.2 22.9 0.034 12.3 3.7 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF724 PF05266.9 EMR69870.1 - 0.31 10.6 25.6 0.48 10.0 7.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) IFT46_B_C PF12317.3 EMR69870.1 - 0.33 10.2 6.4 0.11 11.8 2.4 1.6 1 1 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Fib_alpha PF08702.5 EMR69870.1 - 0.35 11.0 17.8 0.052 13.6 4.2 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.3 EMR69870.1 - 0.37 10.5 28.8 4.9 6.9 1.6 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding NABP PF07990.7 EMR69870.1 - 0.39 9.9 4.7 0.42 9.8 3.3 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DUF3450 PF11932.3 EMR69870.1 - 0.41 9.8 21.8 3.2 6.9 5.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.6 EMR69870.1 - 0.44 10.9 17.7 1.1 9.7 2.9 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Spectrin PF00435.16 EMR69870.1 - 0.5 10.6 25.8 2 8.7 6.8 2.9 1 1 2 3 3 3 0 Spectrin repeat DUF972 PF06156.8 EMR69870.1 - 0.51 10.6 25.6 1.5e+04 -3.8 17.9 3.3 1 1 0 1 1 0 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 EMR69870.1 - 0.54 10.1 21.3 0.65 9.9 0.4 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) KLRAQ PF10205.4 EMR69870.1 - 0.65 10.0 19.9 0.39 10.7 4.4 3.1 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Jnk-SapK_ap_N PF09744.4 EMR69870.1 - 0.79 9.6 27.1 0.25 11.3 12.2 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF1202 PF06717.6 EMR69870.1 - 0.82 8.8 11.7 0.99 8.6 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Seryl_tRNA_N PF02403.17 EMR69870.1 - 0.89 9.6 26.7 0.099 12.6 0.8 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.4 EMR69870.1 - 0.98 8.2 24.2 0.78 8.6 11.3 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2730 PF10805.3 EMR69870.1 - 1 9.1 15.4 0.17 11.6 2.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) BRE1 PF08647.6 EMR69870.1 - 1.1 9.3 25.4 1.4 8.9 4.8 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase MAD PF05557.8 EMR69870.1 - 1.1 7.2 26.2 3.7 5.5 16.6 1.9 1 1 0 1 1 1 0 Mitotic checkpoint protein Baculo_PEP_C PF04513.7 EMR69870.1 - 1.2 8.9 7.7 0.65 9.8 0.3 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4140 PF13600.1 EMR69870.1 - 1.2 9.6 20.6 1.2 9.6 2.3 3.3 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 EMR69870.1 - 1.3 8.5 29.6 0.63 9.5 1.7 4.3 2 1 2 4 4 4 0 Septum formation initiator HalX PF08663.5 EMR69870.1 - 1.4 8.9 19.7 0.75 9.8 1.1 4.2 3 2 1 4 4 4 0 HalX domain WXG100 PF06013.7 EMR69870.1 - 1.5 8.9 14.1 3.8 7.5 0.5 3.6 1 1 1 3 3 3 0 Proteins of 100 residues with WXG HAP1_N PF04849.8 EMR69870.1 - 2.3 7.0 29.3 11 4.8 20.3 2.6 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF4201 PF13870.1 EMR69870.1 - 2.5 7.4 25.8 4.5 6.6 7.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Mnd1 PF03962.10 EMR69870.1 - 2.7 7.5 29.3 2.2 7.9 9.3 2.1 1 1 1 2 2 2 0 Mnd1 family Kinetocho_Slk19 PF12709.2 EMR69870.1 - 2.8 8.0 27.3 0.91 9.6 7.4 3.6 1 1 2 3 3 2 0 Central kinetochore-associated AAA_13 PF13166.1 EMR69870.1 - 2.9 6.2 23.5 16 3.7 16.3 1.9 1 1 0 1 1 1 0 AAA domain Striatin PF08232.7 EMR69870.1 - 3.3 8.0 23.8 7.4 6.8 10.5 2.3 1 1 1 2 2 2 0 Striatin family DUF342 PF03961.8 EMR69870.1 - 3.5 5.9 24.1 0.033 12.6 7.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) TMCO5 PF14992.1 EMR69870.1 - 3.5 6.6 27.7 1.2e+02 1.6 19.2 2.6 1 1 0 1 1 1 0 TMCO5 family DUF641 PF04859.7 EMR69870.1 - 4.4 7.0 19.9 0.24 11.1 2.5 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.7 EMR69870.1 - 4.5 7.1 13.4 3.8 7.3 2.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF745 PF05335.8 EMR69870.1 - 4.7 6.6 15.6 0.18 11.3 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) bZIP_2 PF07716.10 EMR69870.1 - 5 7.0 37.0 1.8 8.4 0.2 5.6 2 2 4 6 6 6 0 Basic region leucine zipper DUF3584 PF12128.3 EMR69870.1 - 5.1 4.2 27.5 9.5 3.3 19.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3829 PF12889.2 EMR69870.1 - 5.1 6.1 18.9 16 4.6 12.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) HSP70 PF00012.15 EMR69870.1 - 5.9 4.6 17.1 7 4.4 11.8 1.2 1 0 0 1 1 1 0 Hsp70 protein FlaF PF07309.6 EMR69870.1 - 6.1 6.7 9.7 1.5 8.7 2.2 2.5 1 1 2 3 3 3 0 Flagellar protein FlaF Nup54 PF13874.1 EMR69870.1 - 6.6 6.3 23.2 10 5.7 0.5 2.9 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 Prefoldin_2 PF01920.15 EMR69870.1 - 7.8 6.3 31.9 0.072 12.8 1.5 4.0 2 1 2 4 4 4 0 Prefoldin subunit V_ATPase_I PF01496.14 EMR69870.1 - 8.3 4.1 21.1 2.3 5.9 6.8 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 EMR69870.1 - 8.5 6.1 32.3 4.5 7.0 18.8 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PP_kinase_N PF13089.1 EMR69871.1 - 0.0081 16.2 0.1 0.85 9.7 0.0 2.6 2 0 0 2 2 2 2 Polyphosphate kinase N-terminal domain Pro_isomerase PF00160.16 EMR69872.1 - 1.2e-46 158.7 1.0 2.2e-46 157.8 0.4 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Trm112p PF03966.11 EMR69873.1 - 4e-18 65.5 0.1 5e-18 65.2 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 EMR69873.1 - 0.034 14.4 0.2 0.057 13.6 0.1 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Peptidase_M19 PF01244.16 EMR69874.1 - 4.6e-102 341.2 0.0 6.2e-102 340.8 0.0 1.2 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.9 EMR69874.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase Fcf1 PF04900.7 EMR69875.1 - 3.8e-37 126.4 0.4 7.9e-24 83.6 0.1 2.5 2 0 0 2 2 2 2 Fcf1 Spt20 PF12090.3 EMR69875.1 - 0.017 14.4 0.2 0.062 12.6 0.0 1.8 1 1 1 2 2 2 0 Spt20 family Glyco_hydro_7 PF00840.15 EMR69875.1 - 0.056 11.8 0.0 0.072 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 BTB PF00651.26 EMR69876.1 - 0.00033 20.5 0.0 0.0013 18.7 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain BNR_2 PF13088.1 EMR69878.1 - 1.5e-10 40.8 0.9 2.6e-06 26.9 0.2 3.2 2 1 1 3 3 3 3 BNR repeat-like domain BNR PF02012.15 EMR69878.1 - 1.6e-06 27.0 11.2 0.34 10.8 0.1 5.1 5 0 0 5 5 5 3 BNR/Asp-box repeat DUF155 PF02582.9 EMR69879.1 - 5.1e-37 127.4 0.0 8.4e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Asp PF00026.18 EMR69880.1 - 2.8e-107 358.6 0.3 3.4e-107 358.3 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMR69880.1 - 3.6e-12 46.5 0.1 1.6e-11 44.4 0.1 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMR69880.1 - 5.1e-07 30.1 0.2 0.02 15.3 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EMR69880.1 - 6.6e-06 25.7 0.0 0.00015 21.3 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Alpha-amylase_C PF02806.13 EMR69880.1 - 0.024 14.7 0.1 3.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain SGL PF08450.7 EMR69881.1 - 0.11 11.8 0.0 9.7 5.4 0.0 2.1 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region SHMT PF00464.14 EMR69882.1 - 2.3e-208 691.4 0.0 2.6e-208 691.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EMR69882.1 - 1.2e-05 24.4 0.0 2.5e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EMR69882.1 - 2.2e-05 23.3 0.0 3.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMR69882.1 - 0.017 14.2 0.0 0.033 13.3 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase GST_N_3 PF13417.1 EMR69883.1 - 8.6e-27 93.1 0.1 1.8e-26 92.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMR69883.1 - 4.9e-18 64.8 0.1 4.4e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMR69883.1 - 4.9e-09 36.2 0.0 8e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR69883.1 - 3.9e-07 29.8 0.4 1.2e-06 28.3 0.3 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMR69883.1 - 0.0053 16.7 0.0 0.0097 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR69883.1 - 0.013 15.9 0.1 0.057 13.8 0.0 2.1 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EMR69883.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin p450 PF00067.17 EMR69885.1 - 1.3e-56 192.0 0.0 1.6e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 EMR69886.1 - 1.1e-81 274.4 0.1 2.7e-81 273.0 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMR69886.1 - 1.5e-09 38.6 0.0 4.5e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.21 EMR69887.1 - 5.8e-24 84.1 0.1 1e-23 83.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR69887.1 - 3.8e-21 74.8 0.2 8.7e-21 73.7 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMR69887.1 - 0.00059 20.7 0.1 0.0013 19.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMR69887.1 - 0.16 11.1 0.7 0.29 10.2 0.2 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PRCC PF10253.4 EMR69888.1 - 4.5e-37 128.4 1.8 4.5e-37 128.4 1.2 3.3 3 1 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting HET PF06985.6 EMR69889.1 - 4.6e-16 59.2 4.0 5.7e-14 52.4 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EMR69890.1 - 2.2e-32 112.1 38.0 1.3e-31 109.6 26.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Erythro_esteras PF05139.9 EMR69892.1 - 0.0075 15.5 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 Erythromycin esterase Fungal_trans PF04082.13 EMR69895.1 - 1.5e-19 69.9 0.0 2.2e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.18 EMR69896.1 - 3.5e-75 252.9 37.7 9.6e-42 143.2 5.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMR69896.1 - 8.7e-67 223.6 0.0 4e-33 114.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EMR69896.1 - 6.2e-16 58.2 0.8 2.9e-06 26.6 0.0 4.3 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMR69896.1 - 1.6e-10 41.4 0.1 0.0036 17.3 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EMR69896.1 - 2.3e-08 33.4 0.2 0.0066 15.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EMR69896.1 - 5e-08 33.7 0.0 0.015 16.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMR69896.1 - 5.2e-07 29.8 4.0 0.0031 17.5 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EMR69896.1 - 8.6e-07 29.1 1.8 0.048 13.7 0.1 4.2 2 2 0 3 3 3 2 AAA domain DUF258 PF03193.11 EMR69896.1 - 2.7e-06 26.6 0.0 0.0023 17.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EMR69896.1 - 3.1e-06 26.8 4.1 0.0028 17.2 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EMR69896.1 - 1.8e-05 24.2 0.8 0.25 10.7 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 EMR69896.1 - 2.7e-05 24.4 0.0 0.3 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EMR69896.1 - 3.4e-05 22.6 2.3 0.002 16.7 0.0 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA PF00004.24 EMR69896.1 - 6.7e-05 23.1 0.0 0.15 12.2 0.0 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EMR69896.1 - 0.00011 21.8 0.2 0.044 13.4 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_23 PF13476.1 EMR69896.1 - 0.00015 22.1 0.1 0.12 12.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EMR69896.1 - 0.0003 20.6 0.1 1.1 9.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EMR69896.1 - 0.0011 18.4 0.3 3.2 7.0 0.0 3.2 3 0 0 3 3 3 1 AAA-like domain AAA_5 PF07728.9 EMR69896.1 - 0.0016 18.2 0.2 0.86 9.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EMR69896.1 - 0.002 18.0 5.9 1.1 9.2 0.1 4.1 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EMR69896.1 - 0.0026 17.6 0.0 1.1 9.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 EMR69896.1 - 0.0029 17.4 0.1 0.22 11.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EMR69896.1 - 0.0039 17.1 0.2 1.5 8.7 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EMR69896.1 - 0.0048 16.0 0.1 0.52 9.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.9 EMR69896.1 - 0.021 14.5 0.1 8.6 6.0 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EMR69896.1 - 0.022 14.2 2.8 3.3 7.1 0.0 3.3 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 EMR69896.1 - 0.064 12.7 0.0 6.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 EMR69896.1 - 0.17 12.1 0.0 17 5.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.1 EMR69896.1 - 0.39 9.6 0.0 0.69 8.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF2238 PF09997.4 EMR69896.1 - 0.67 9.3 16.6 1.7 7.9 0.9 3.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2238) Apolipoprotein PF01442.13 EMR69897.1 - 0.0001 21.8 5.2 0.13 11.7 0.5 3.2 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain Prominin PF05478.6 EMR69897.1 - 0.037 11.5 5.4 0.91 6.9 0.5 2.5 1 1 1 3 3 3 0 Prominin Globin PF00042.17 EMR69897.1 - 0.062 13.6 0.7 3.7 7.9 0.0 3.5 2 1 1 3 3 3 0 Globin XH PF03469.9 EMR69897.1 - 0.11 12.1 0.1 0.11 12.1 0.0 3.9 2 1 2 4 4 4 0 XH domain HBS1_N PF08938.5 EMR69897.1 - 0.3 11.2 4.0 1.9 8.6 0.4 3.1 3 1 0 3 3 3 0 HBS1 N-terminus TipAS PF07739.8 EMR69897.1 - 0.3 11.4 15.6 1.9 8.8 0.2 4.5 4 1 1 5 5 5 0 TipAS antibiotic-recognition domain HisKA_3 PF07730.8 EMR69897.1 - 0.31 11.4 4.3 9.3 6.6 0.2 4.2 4 1 0 4 4 4 0 Histidine kinase Spore_III_AB PF09548.5 EMR69897.1 - 0.62 9.7 6.7 1.2 8.8 0.4 3.4 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF883 PF05957.8 EMR69897.1 - 0.85 10.0 11.8 21 5.5 1.2 5.2 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) ATC_hydrolase PF14196.1 EMR69897.1 - 1.1 9.6 6.7 4.3 7.7 0.5 3.5 2 1 1 3 3 3 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Phasin_2 PF09361.5 EMR69897.1 - 1.2 9.2 11.9 41 4.2 0.8 4.8 3 3 1 4 4 4 0 Phasin protein RsbU_N PF08673.5 EMR69898.1 - 0.019 14.9 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain SnoaL_2 PF12680.2 EMR69898.1 - 0.11 12.9 1.5 0.34 11.3 0.4 2.3 2 1 0 2 2 2 0 SnoaL-like domain Pyr_redox PF00070.22 EMR69899.1 - 2.4e-13 50.2 0.0 1.4e-09 38.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR69899.1 - 2.9e-06 27.3 0.0 0.055 13.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR69899.1 - 6.5e-06 26.3 0.0 0.65 10.0 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR69899.1 - 0.00082 18.3 0.0 0.019 13.8 0.1 2.2 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EMR69899.1 - 0.024 14.8 0.0 0.17 12.1 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EMR69899.1 - 0.024 13.5 0.1 0.054 12.4 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMR69899.1 - 0.073 13.1 0.0 5 7.2 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR69899.1 - 0.11 11.3 0.1 0.72 8.6 0.0 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EMR69899.1 - 0.14 11.1 0.2 8 5.3 0.3 2.2 2 0 0 2 2 2 0 FAD binding domain Glyco_hydro_18 PF00704.23 EMR69900.1 - 1.3e-15 57.7 1.0 1.9e-14 53.9 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 MIF4G PF02854.14 EMR69901.1 - 3.9e-28 98.2 0.5 3.9e-28 98.2 0.3 1.9 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EMR69901.1 - 7.5e-23 80.3 0.0 3.6e-22 78.1 0.0 2.2 2 0 0 2 2 2 1 MA3 domain CDC45 PF02724.9 EMR69901.1 - 1.6 6.6 9.3 2.8 5.8 6.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DPM2 PF07297.7 EMR69902.1 - 1.1e-33 115.3 2.6 1.2e-33 115.1 1.8 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4229 PF14012.1 EMR69902.1 - 0.00033 20.4 0.6 0.00033 20.4 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) PIG-P PF08510.7 EMR69902.1 - 0.0012 18.4 1.5 0.0014 18.2 1.1 1.1 1 0 0 1 1 1 1 PIG-P COX14 PF14880.1 EMR69902.1 - 0.015 14.9 3.3 0.04 13.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF4083 PF13314.1 EMR69902.1 - 0.016 15.0 0.1 0.016 15.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Cation_efflux PF01545.16 EMR69902.1 - 0.066 12.2 0.4 0.074 12.1 0.3 1.0 1 0 0 1 1 1 0 Cation efflux family DiS_P_DiS PF06750.8 EMR69902.1 - 0.12 12.2 0.5 0.17 11.6 0.0 1.5 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Herpes_UL43 PF05072.8 EMR69902.1 - 0.24 10.0 2.0 0.17 10.6 0.2 1.5 2 0 0 2 2 2 0 Herpesvirus UL43 protein TPPK_C PF12555.3 EMR69902.1 - 1.8 8.3 8.1 3.9 7.2 0.8 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DUF1049 PF06305.6 EMR69902.1 - 2.9 7.4 8.8 0.14 11.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Acetyltransf_8 PF13523.1 EMR69903.1 - 9.9e-39 132.6 0.5 1.5e-38 132.0 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMR69903.1 - 0.026 14.6 0.1 0.052 13.7 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Kelch_3 PF13415.1 EMR69904.1 - 2.9e-19 68.6 12.3 7.7e-09 35.4 0.0 5.2 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EMR69904.1 - 2.7e-15 55.9 1.1 4.1e-08 33.0 0.0 3.8 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 EMR69904.1 - 2.8e-15 55.7 6.1 3.1e-05 23.6 0.0 4.6 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EMR69904.1 - 1.6e-10 40.6 1.8 0.00073 19.6 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EMR69904.1 - 9.6e-09 34.6 6.4 1.4e-06 27.6 0.0 4.1 4 1 0 4 4 4 2 Kelch motif DUF4110 PF13422.1 EMR69904.1 - 1.3e-08 34.5 6.1 1.3e-08 34.5 4.2 3.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_2 PF07646.10 EMR69904.1 - 4.4e-08 32.5 6.2 0.00022 20.8 0.1 4.8 3 2 0 3 3 3 2 Kelch motif Sporozoite_P67 PF05642.6 EMR69904.1 - 1.2 6.9 11.9 2.1 6.0 8.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIF_alpha PF05793.7 EMR69904.1 - 1.8 6.8 32.5 1.8 6.8 10.4 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TPR_11 PF13414.1 EMR69905.1 - 0.00011 21.7 5.5 0.0004 19.9 0.0 3.8 4 0 0 4 4 4 1 TPR repeat AAA_16 PF13191.1 EMR69905.1 - 0.0027 17.7 0.2 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain TPR_2 PF07719.12 EMR69905.1 - 0.0093 15.8 6.6 8.8 6.5 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_19 PF13245.1 EMR69905.1 - 0.01 15.6 0.1 0.047 13.4 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EMR69905.1 - 0.016 15.3 0.0 0.24 11.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain TPR_17 PF13431.1 EMR69905.1 - 0.042 14.0 0.1 0.49 10.7 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMR69905.1 - 0.053 14.2 6.7 0.14 12.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMR69905.1 - 0.1 12.5 0.1 0.1 12.5 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat bZIP_1 PF00170.16 EMR69907.1 - 0.084 12.8 7.8 0.48 10.4 5.4 2.2 1 1 0 1 1 1 0 bZIP transcription factor PAT1 PF09770.4 EMR69907.1 - 3 5.9 20.7 0.21 9.7 10.7 1.5 1 1 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3546 PF12066.3 EMR69908.1 - 1.3e-26 92.7 1.9 1.3e-26 92.7 1.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 EMR69908.1 - 1.4e-24 85.4 0.1 3.4e-24 84.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 EMR69908.1 - 1.1e-10 42.1 2.2 2.5e-10 40.9 1.5 1.6 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF3080 PF11279.3 EMR69908.1 - 0.093 11.8 0.1 1.2 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) SUR7 PF06687.7 EMR69909.1 - 1.6e-29 103.0 0.2 1.9e-29 102.7 0.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EMR69909.1 - 0.00023 21.0 1.1 0.00023 21.0 0.7 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Claudin_2 PF13903.1 EMR69909.1 - 0.05 13.2 0.0 0.05 13.2 0.0 2.9 2 1 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF1218 PF06749.7 EMR69909.1 - 0.056 13.8 4.9 2 8.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF4097 PF13349.1 EMR69909.1 - 1.9 8.0 7.5 20 4.6 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4097) DUF2189 PF09955.4 EMR69909.1 - 1.9 8.4 15.9 1.3 8.9 0.9 3.1 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2189) LXG PF04740.7 EMR69910.1 - 0.013 15.2 0.1 0.016 14.9 0.1 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily HAMP PF00672.20 EMR69910.1 - 0.021 14.9 0.8 0.11 12.6 0.5 2.2 1 1 0 1 1 1 0 HAMP domain Hemerythrin PF01814.18 EMR69910.1 - 0.03 14.4 0.8 0.61 10.2 0.1 2.1 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Dioxygenase_C PF00775.16 EMR69911.1 - 2e-12 46.7 0.0 3.4e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase R3H PF01424.17 EMR69912.1 - 1.7e-12 46.8 0.1 3e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 R3H domain F-box-like_2 PF13013.1 EMR69913.1 - 0.038 13.7 0.1 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain Mito_carr PF00153.22 EMR69914.1 - 2.8e-62 206.4 0.2 3.3e-20 71.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WSC PF01822.14 EMR69915.1 - 2e-54 181.4 40.7 3e-19 68.7 4.9 3.3 3 0 0 3 3 3 3 WSC domain Glyoxal_oxid_N PF07250.6 EMR69915.1 - 3.4e-26 91.7 0.0 9e-25 87.1 0.0 3.0 3 1 1 4 4 4 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EMR69915.1 - 3.8e-22 78.2 0.0 7.4e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.10 EMR69915.1 - 0.0074 16.0 0.5 6.2 6.7 0.0 4.1 4 0 0 4 4 4 1 Kelch motif TspO_MBR PF03073.10 EMR69916.1 - 5.7e-36 123.2 6.5 9.2e-36 122.5 4.5 1.3 1 0 0 1 1 1 1 TspO/MBR family MscL PF01741.13 EMR69917.1 - 2.5e-12 47.0 2.9 5.3e-12 46.0 2.0 1.6 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-BED PF02892.10 EMR69917.1 - 0.014 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 BED zinc finger Solute_trans_a PF03619.11 EMR69917.1 - 0.065 12.5 0.2 0.096 11.9 0.1 1.1 1 0 0 1 1 1 0 Organic solute transporter Ostalpha DUF2339 PF10101.4 EMR69917.1 - 0.26 9.5 1.7 0.35 9.1 1.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) RTA1 PF04479.8 EMR69918.1 - 1.6e-24 86.6 0.8 2.4e-24 86.1 0.6 1.2 1 0 0 1 1 1 1 RTA1 like protein RRN3 PF05327.6 EMR69919.1 - 7.2e-164 546.0 0.1 7.2e-164 546.0 0.1 1.3 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DUF885 PF05960.6 EMR69919.1 - 0.0087 15.2 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) zf-HIT PF04438.11 EMR69920.1 - 3e-09 36.3 4.4 4.4e-09 35.8 3.1 1.3 1 0 0 1 1 1 1 HIT zinc finger DpnD-PcfM PF14207.1 EMR69921.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 DpnD/PcfM-like protein Ribonuc_L-PSP PF01042.16 EMR69922.1 - 3.5e-24 84.8 0.0 4.2e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1320 PF07030.7 EMR69922.1 - 0.045 13.4 0.1 0.066 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) BaffR-Tall_bind PF09256.5 EMR69923.1 - 0.022 14.3 0.2 0.046 13.3 0.2 1.5 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding AAA PF00004.24 EMR69924.1 - 7e-37 126.5 0.0 5.3e-36 123.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMR69924.1 - 3.9e-08 33.5 1.7 0.00026 21.0 0.0 3.0 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EMR69924.1 - 3.9e-07 30.2 0.3 9e-05 22.6 0.2 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMR69924.1 - 6.9e-06 25.2 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EMR69924.1 - 2.4e-05 25.1 1.3 0.00017 22.3 0.9 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMR69924.1 - 0.0002 21.2 0.0 0.00048 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMR69924.1 - 0.00028 20.7 0.0 0.00089 19.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMR69924.1 - 0.00094 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EMR69924.1 - 0.001 18.5 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EMR69924.1 - 0.0013 18.4 0.1 0.0041 16.8 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 EMR69924.1 - 0.0014 18.6 0.0 0.0049 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EMR69924.1 - 0.0021 17.4 2.4 0.25 10.6 0.1 3.1 2 1 0 3 3 3 1 AAA domain TIP49 PF06068.8 EMR69924.1 - 0.0022 16.8 0.0 0.0037 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 EMR69924.1 - 0.0026 17.9 0.3 0.017 15.2 0.1 2.4 2 1 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 EMR69924.1 - 0.0038 17.5 1.0 0.01 16.1 0.0 2.3 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMR69924.1 - 0.0047 16.6 0.8 0.019 14.6 0.1 2.4 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EMR69924.1 - 0.012 15.5 0.1 0.058 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EMR69924.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EMR69924.1 - 0.015 14.7 0.3 14 4.9 0.0 3.3 2 2 1 3 3 3 0 AAA-like domain AAA_24 PF13479.1 EMR69924.1 - 0.023 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EMR69924.1 - 0.026 14.1 0.1 0.81 9.3 0.0 2.5 1 1 1 2 2 2 0 NACHT domain DUF815 PF05673.8 EMR69924.1 - 0.039 12.8 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EMR69924.1 - 0.059 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 EMR69924.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 EMR69924.1 - 0.068 12.1 0.1 0.18 10.7 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IPT PF01745.11 EMR69924.1 - 0.083 12.0 0.1 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase Arch_ATPase PF01637.13 EMR69924.1 - 0.087 12.5 1.4 1.5 8.4 0.0 2.6 2 1 1 3 3 2 0 Archaeal ATPase Zeta_toxin PF06414.7 EMR69924.1 - 0.1 11.6 0.9 0.39 9.7 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin WSC PF01822.14 EMR69925.1 - 2.1e-15 56.3 7.0 2.9e-15 55.9 4.8 1.2 1 0 0 1 1 1 1 WSC domain DUF1772 PF08592.6 EMR69926.1 - 0.14 11.9 1.2 0.62 9.7 0.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) ISN1 PF06437.6 EMR69927.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase zf-C2H2 PF00096.21 EMR69928.1 - 0.00033 20.8 2.6 0.0053 17.0 0.3 3.0 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR69928.1 - 0.00087 19.4 2.9 0.0038 17.4 0.3 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMR69928.1 - 0.09 13.1 0.8 0.63 10.4 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double domain COX4 PF02936.9 EMR69929.1 - 5e-48 162.4 0.1 5.9e-48 162.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Synthase_beta PF11421.3 EMR69929.1 - 0.038 14.6 6.6 0.12 13.0 4.6 1.8 1 1 0 1 1 1 0 ATP synthase F1 beta subunit DUF1104 PF06518.6 EMR69929.1 - 0.069 13.2 0.2 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Bundlin PF05307.6 EMR69930.1 - 0.33 10.8 3.2 3.3 7.6 0.3 2.3 1 1 1 2 2 2 0 Bundlin Orthopox_F7 PF05813.7 EMR69934.1 - 0.038 13.8 0.9 0.052 13.4 0.6 1.2 1 0 0 1 1 1 0 Orthopoxvirus F7 protein Sugar_tr PF00083.19 EMR69935.1 - 7.9e-128 426.8 26.6 9e-128 426.6 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR69935.1 - 1.6e-20 73.1 55.9 4.2e-18 65.1 21.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Mus7 PF09462.5 EMR69936.1 - 1.9e-17 63.3 0.0 2.6e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family SprB PF13573.1 EMR69936.1 - 1.2 8.8 4.4 2.1 7.9 0.9 2.3 2 0 0 2 2 2 0 SprB repeat FixO PF02433.10 EMR69937.1 - 0.077 12.3 1.2 0.091 12.1 0.8 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO DDHD PF02862.12 EMR69937.1 - 0.26 11.0 3.0 0.27 10.9 2.1 1.2 1 0 0 1 1 1 0 DDHD domain ABC_trans_N PF14510.1 EMR69937.1 - 0.31 11.1 2.5 1.4 9.0 1.6 1.9 1 1 1 2 2 2 0 ABC-transporter extracellular N-terminal AAA_23 PF13476.1 EMR69937.1 - 0.36 11.1 11.5 0.41 10.9 8.0 1.2 1 0 0 1 1 1 0 AAA domain Mpp10 PF04006.7 EMR69937.1 - 0.44 8.8 21.1 0.45 8.8 14.7 1.0 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.7 EMR69937.1 - 0.46 8.3 18.1 0.47 8.3 12.5 1.0 1 0 0 1 1 1 0 Nop14-like family Sec62 PF03839.11 EMR69937.1 - 0.62 9.4 2.0 0.75 9.1 1.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Daxx PF03344.10 EMR69937.1 - 3.4 6.0 22.9 4 5.7 15.9 1.0 1 0 0 1 1 1 0 Daxx Family V_ATPase_I PF01496.14 EMR69937.1 - 3.5 5.3 7.2 3.7 5.2 5.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YqfQ PF14181.1 EMR69937.1 - 3.8 7.5 8.4 4.7 7.2 5.8 1.3 1 0 0 1 1 1 0 YqfQ-like protein Spore_coat_CotO PF14153.1 EMR69937.1 - 4.1 6.8 16.0 4.8 6.5 11.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Usp PF00582.21 EMR69937.1 - 4.2 7.5 8.0 6 7.0 5.5 1.3 1 0 0 1 1 1 0 Universal stress protein family RNA_pol_3_Rpc31 PF11705.3 EMR69937.1 - 5 6.9 22.4 6.3 6.6 15.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.7 EMR69937.1 - 5.1 6.2 17.7 5.6 6.1 12.3 1.0 1 0 0 1 1 1 0 SDA1 VID27 PF08553.5 EMR69937.1 - 6.5 4.8 15.3 7.2 4.7 10.6 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Pilt PF15453.1 EMR69937.1 - 7.5 6.1 9.4 8.6 5.9 6.5 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions AA_permease_N PF08403.5 EMR69937.1 - 8.2 5.8 7.5 16 4.8 3.9 2.3 2 1 0 2 2 2 0 Amino acid permease N-terminal DUF1510 PF07423.6 EMR69937.1 - 9.4 5.5 15.5 11 5.2 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ABC_tran PF00005.22 EMR69939.1 - 5.9e-52 175.6 0.0 2.8e-28 98.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMR69939.1 - 7.3e-27 94.4 15.0 6.9e-15 55.2 0.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EMR69939.1 - 5.1e-11 42.2 1.6 0.072 12.3 0.1 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMR69939.1 - 5.3e-10 39.7 0.2 0.45 10.4 0.0 4.3 2 2 1 3 3 3 3 AAA domain AAA_23 PF13476.1 EMR69939.1 - 3.7e-08 33.9 0.2 3.1e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EMR69939.1 - 6.1e-08 32.0 1.2 0.01 15.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EMR69939.1 - 1.1e-07 31.4 0.0 0.007 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EMR69939.1 - 4e-07 29.7 0.0 0.016 14.7 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 EMR69939.1 - 1.3e-06 27.6 0.2 0.0054 15.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 EMR69939.1 - 2.6e-06 27.4 2.3 0.0013 18.6 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_10 PF12846.2 EMR69939.1 - 3.7e-06 26.5 0.1 0.02 14.3 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain Miro PF08477.8 EMR69939.1 - 2e-05 25.0 0.0 0.24 11.8 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 EMR69939.1 - 5.3e-05 23.1 4.1 0.028 14.2 0.0 2.7 3 0 0 3 3 2 2 Dynamin family MMR_HSR1 PF01926.18 EMR69939.1 - 5.4e-05 23.1 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 EMR69939.1 - 6.4e-05 22.6 0.6 0.058 13.1 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EMR69939.1 - 0.0001 22.4 1.0 0.64 10.1 0.1 3.4 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EMR69939.1 - 0.00014 21.9 1.0 0.61 10.0 0.2 2.9 3 1 0 3 3 2 2 AAA ATPase domain T2SE PF00437.15 EMR69939.1 - 0.00017 20.5 0.0 0.2 10.5 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 EMR69939.1 - 0.00033 21.4 0.0 0.57 10.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMR69939.1 - 0.00037 20.2 0.5 0.59 9.7 0.1 2.5 2 0 0 2 2 2 2 NACHT domain SbcCD_C PF13558.1 EMR69939.1 - 0.0005 19.9 1.0 0.79 9.6 0.0 3.2 3 0 0 3 3 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 EMR69939.1 - 0.0016 17.4 1.3 2.8 6.6 0.1 3.5 3 1 0 3 3 3 2 NB-ARC domain Viral_helicase1 PF01443.13 EMR69939.1 - 0.002 17.7 0.0 2.5 7.5 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 EMR69939.1 - 0.0023 17.8 0.0 3.5 7.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMR69939.1 - 0.0037 16.9 1.2 5.6 6.6 0.0 4.2 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) AIG1 PF04548.11 EMR69939.1 - 0.0046 16.0 0.9 1.6 7.7 0.0 2.4 2 0 0 2 2 2 1 AIG1 family AAA_18 PF13238.1 EMR69939.1 - 0.0054 17.0 0.1 6.7 7.0 0.0 3.1 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.12 EMR69939.1 - 0.006 16.1 1.4 3.1 7.2 0.1 3.4 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein Septin PF00735.13 EMR69939.1 - 0.0065 15.5 0.1 2.6 6.9 0.0 2.4 2 0 0 2 2 2 1 Septin Pox_A32 PF04665.7 EMR69939.1 - 0.0078 15.5 1.7 0.85 8.8 0.1 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein cobW PF02492.14 EMR69939.1 - 0.015 14.7 2.4 2.5 7.4 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EMR69939.1 - 0.024 14.3 0.2 1.3 8.6 0.0 3.1 3 1 0 3 3 3 0 Archaeal ATPase ATP-synt_ab PF00006.20 EMR69939.1 - 0.024 14.1 0.0 7.9 5.9 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 EMR69939.1 - 0.035 13.6 0.1 3.5 7.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 EMR69939.1 - 0.048 12.6 0.3 0.27 10.2 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 EMR69939.1 - 0.071 13.2 0.1 12 6.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 EMR69939.1 - 0.088 12.7 0.1 17 5.3 0.0 3.4 4 0 0 4 4 3 0 AAA domain ABC_ATPase PF09818.4 EMR69939.1 - 0.11 11.0 0.6 41 2.5 0.0 3.5 4 0 0 4 4 4 0 Predicted ATPase of the ABC class DEAD PF00270.24 EMR69939.1 - 0.13 11.7 0.0 7.4 6.0 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase DAP3 PF10236.4 EMR69939.1 - 0.17 10.8 0.8 12 4.7 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 PduV-EutP PF10662.4 EMR69939.1 - 0.84 9.1 3.2 23 4.4 0.1 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Glyco_hydro_43 PF04616.9 EMR69940.1 - 7.5e-23 81.0 9.6 7.6e-09 35.0 2.7 3.7 3 1 1 4 4 4 3 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EMR69940.1 - 0.013 14.8 0.5 0.069 12.5 0.0 2.3 3 0 0 3 3 3 0 Glycosyl hydrolases family 32 N-terminal domain DUF848 PF05852.6 EMR69943.1 - 0.026 14.3 1.5 0.066 13.0 1.0 1.6 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) HAD PF12710.2 EMR69944.1 - 0.023 14.8 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glyco_hydro_20 PF00728.17 EMR69946.1 - 1.1e-29 103.7 1.0 5.7e-29 101.3 0.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain RIO1 PF01163.17 EMR69947.1 - 4.6e-67 225.0 0.0 4.6e-67 225.0 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EMR69947.1 - 9e-05 22.3 0.1 0.16 11.7 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EMR69947.1 - 0.001 18.1 0.1 0.11 11.5 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol_phi PF04931.8 EMR69948.1 - 4e-45 153.9 49.7 3.7e-32 111.0 29.8 4.2 3 2 0 3 3 3 3 DNA polymerase phi DUF2435 PF10363.4 EMR69948.1 - 0.02 14.8 0.0 2 8.3 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) DHDPS PF00701.17 EMR69949.1 - 1.3e-52 178.2 0.0 1.5e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Proteasome PF00227.21 EMR69951.1 - 8.4e-44 149.1 0.0 2.4e-30 105.2 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EMR69951.1 - 9.2e-12 44.0 0.0 1.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Mito_carr PF00153.22 EMR69952.1 - 0.064 12.9 0.2 0.22 11.2 0.1 1.8 1 1 0 1 1 1 0 Mitochondrial carrier protein CwfJ_C_2 PF04676.9 EMR69953.1 - 4.4e-22 78.4 0.1 1.1e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 EMR69953.1 - 1.1e-09 37.9 0.0 2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Rhodanese PF00581.15 EMR69954.1 - 1.7e-12 47.6 0.0 3.7e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain FdsD PF11390.3 EMR69955.1 - 0.087 12.9 0.4 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD Chromo PF00385.19 EMR69956.1 - 8.1e-09 35.0 1.1 2.1e-07 30.5 0.5 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PIN_3 PF13470.1 EMR69956.1 - 6.6 7.4 7.2 90 3.7 5.0 2.4 1 1 0 1 1 1 0 PIN domain Acetyltransf_1 PF00583.19 EMR69957.1 - 8.4e-13 48.1 0.1 1.3e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EMR69957.1 - 6e-08 32.3 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EMR69957.1 - 4.5e-07 30.0 0.1 1.1e-06 28.7 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR69957.1 - 4.2e-06 26.6 0.0 0.00018 21.3 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR69957.1 - 1.2e-05 25.3 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMR69957.1 - 7.5e-05 22.5 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 EMR69957.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sporozoite_P67 PF05642.6 EMR69957.1 - 0.066 11.0 0.6 0.082 10.7 0.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DRIM PF07539.7 EMR69958.1 - 1e-41 141.6 0.0 7.4e-41 138.8 0.0 2.5 2 0 0 2 2 2 1 Down-regulated in metastasis Vac14_Fab1_bd PF12755.2 EMR69958.1 - 0.0021 18.4 1.6 1.7 9.0 0.0 4.5 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EMR69958.1 - 0.61 10.3 19.2 1.3 9.3 0.0 8.8 11 0 0 11 11 11 0 HEAT repeat Ricin_B_lectin PF00652.17 EMR69959.1 - 3.2e-11 43.3 0.2 2.4e-10 40.5 0.2 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EMR69959.1 - 5.2e-08 33.1 0.1 2.3e-07 31.1 0.1 1.8 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Amidoligase_2 PF12224.3 EMR69960.1 - 7.1e-21 74.9 0.1 8.7e-19 68.1 0.1 2.1 1 1 0 1 1 1 1 Putative amidoligase enzyme DAO PF01266.19 EMR69961.1 - 2.7e-47 161.4 0.0 3.1e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR69961.1 - 4.1e-06 26.7 0.0 9.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMR69961.1 - 0.00037 19.4 0.0 0.01 14.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EMR69961.1 - 0.00051 20.3 0.0 0.0069 16.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR69961.1 - 0.00089 18.4 0.0 0.016 14.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EMR69961.1 - 0.0026 17.6 0.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CgtA PF06306.6 EMR69961.1 - 0.0034 16.6 0.0 0.54 9.4 0.0 2.1 2 0 0 2 2 2 1 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) FAD_binding_3 PF01494.14 EMR69961.1 - 0.0053 15.8 0.0 0.014 14.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EMR69961.1 - 0.0084 14.6 0.0 1.4 7.3 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_7 PF13241.1 EMR69961.1 - 0.017 15.3 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Amino_oxidase PF01593.19 EMR69961.1 - 0.021 13.8 0.0 0.065 12.2 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EMR69961.1 - 0.024 14.7 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMR69961.1 - 0.033 12.8 0.0 0.071 11.7 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.15 EMR69961.1 - 0.037 14.1 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EMR69961.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.17 EMR69961.1 - 0.081 11.7 0.1 9.6 4.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A ThiF PF00899.16 EMR69961.1 - 0.092 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 ThiF family GST_C_2 PF13410.1 EMR69962.1 - 2.4e-09 36.9 0.0 4.8e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMR69962.1 - 1.5e-07 31.4 0.0 3.7e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMR69962.1 - 2.1e-07 31.0 0.0 4.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR69962.1 - 2.8e-07 30.4 0.0 6.3e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMR69962.1 - 4.7e-07 29.7 0.0 8.5e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMR69962.1 - 0.00045 20.6 0.0 0.0008 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Drf_GBD PF06371.8 EMR69963.1 - 8.2e-14 51.3 0.9 5.2e-12 45.5 0.6 2.5 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain MFS_1 PF07690.11 EMR69964.1 - 1.2e-08 34.0 20.4 0.00011 21.0 0.1 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4386 PF14329.1 EMR69964.1 - 0.018 14.5 2.0 0.12 11.7 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4386) UCR_hinge PF02320.11 EMR69966.1 - 1.4e-27 95.3 7.6 2.9e-27 94.3 5.3 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Ribosomal_60s PF00428.14 EMR69966.1 - 0.0037 17.6 8.8 0.0081 16.5 6.1 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein RR_TM4-6 PF06459.7 EMR69966.1 - 0.57 10.0 15.5 0.67 9.8 10.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Senescence_reg PF04520.8 EMR69966.1 - 2.4 8.6 9.9 3.7 8.0 6.8 1.4 1 0 0 1 1 1 0 Senescence regulator DDHD PF02862.12 EMR69966.1 - 5.3 6.7 8.7 7 6.3 6.0 1.2 1 0 0 1 1 1 0 DDHD domain Nexin_C PF08628.7 EMR69967.1 - 2.8e-31 107.9 0.8 8.1e-31 106.4 0.0 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EMR69967.1 - 8.9e-21 73.8 0.6 1.8e-20 72.7 0.4 1.5 1 0 0 1 1 1 1 PX domain T2SJ PF11612.3 EMR69967.1 - 0.012 15.4 0.3 0.029 14.1 0.2 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J Lge1 PF11488.3 EMR69967.1 - 0.12 12.5 2.4 1.3 9.2 0.0 2.7 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 MFS_1 PF07690.11 EMR69968.1 - 2.3e-24 85.7 35.5 4.6e-24 84.7 24.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF912 PF06024.7 EMR69968.1 - 0.19 11.8 0.0 0.5 10.4 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MFS_1 PF07690.11 EMR69969.1 - 3.8e-19 68.6 39.3 3.8e-19 68.6 27.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3487 PF11990.3 EMR69969.1 - 4.1 6.8 6.8 1.6 8.1 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF3446 PF11928.3 EMR69970.1 - 0.63 10.2 11.2 0.4 10.8 4.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) RRM_1 PF00076.17 EMR69971.1 - 1.6e-22 78.8 0.0 8.6e-11 41.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR69971.1 - 2.2e-17 62.8 0.0 7.5e-08 32.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR69971.1 - 6e-15 54.8 0.0 6.9e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 EMR69972.1 - 1.5e-21 76.5 24.5 5e-17 61.6 14.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_4 PF02390.12 EMR69973.1 - 3e-56 189.6 0.0 4.2e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EMR69973.1 - 6e-05 23.5 0.0 9.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR69973.1 - 8.2e-05 22.6 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EMR69973.1 - 0.0015 17.5 0.1 0.0075 15.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) MTS PF05175.9 EMR69973.1 - 0.0026 17.1 0.0 0.0087 15.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EMR69973.1 - 0.016 15.6 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMR69973.1 - 0.047 14.1 0.0 0.33 11.4 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMR69973.1 - 0.052 13.9 0.2 0.18 12.1 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Homoserine_dh PF00742.14 EMR69974.1 - 6.9e-53 178.9 0.0 9e-53 178.6 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EMR69974.1 - 5e-17 62.3 0.0 8.6e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain RNA_helicase PF00910.17 EMR69974.1 - 0.094 12.8 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF4078 PF13300.1 EMR69975.1 - 1.9e-07 31.0 0.1 1.9e-07 31.0 0.0 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4078) Cwf_Cwc_15 PF04889.7 EMR69975.1 - 0.076 12.7 21.4 0.078 12.6 11.0 2.1 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Chorion_2 PF03964.10 EMR69975.1 - 0.49 10.9 6.9 0.081 13.4 1.3 2.2 2 1 0 2 2 2 0 Chorion family 2 Spt5_N PF11942.3 EMR69975.1 - 1 10.0 21.2 9.2 6.9 4.5 2.8 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Hydantoinase_B PF02538.9 EMR69976.1 - 1.1e-174 581.5 0.0 1.8e-174 580.8 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EMR69976.1 - 1.7e-89 299.8 0.9 2.2e-89 299.4 0.1 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EMR69976.1 - 1.4e-59 200.5 0.6 2.6e-58 196.4 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region AP_endonuc_2 PF01261.19 EMR69976.1 - 0.072 12.3 0.0 2.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Acyltransferase PF01553.16 EMR69977.1 - 6.4e-10 38.5 0.0 9.8e-09 34.7 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase DUF2263 PF10021.4 EMR69978.1 - 9.5e-23 80.8 0.2 3.9e-20 72.3 0.1 2.3 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2263) BBE PF08031.7 EMR69979.1 - 0.0019 18.0 0.3 0.0049 16.7 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_24 PF13578.1 EMR69981.1 - 1.9e-14 54.3 0.0 3e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EMR69981.1 - 1.6e-07 30.6 0.0 3.2e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase GCD14 PF08704.5 EMR69981.1 - 0.0092 15.5 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit CmcI PF04989.7 EMR69981.1 - 0.029 13.6 0.0 0.043 13.1 0.0 1.4 1 1 0 1 1 1 0 Cephalosporin hydroxylase Ribosomal_L30_N PF08079.7 EMR69982.1 - 0.48 10.4 1.9 1.2 9.1 1.3 1.6 1 1 0 1 1 1 0 Ribosomal L30 N-terminal domain SGL PF08450.7 EMR69983.1 - 1.4e-33 116.2 0.0 1.9e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EMR69983.1 - 0.0014 18.6 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 2 Strictosidine synthase PQQ_3 PF13570.1 EMR69983.1 - 0.033 14.4 1.1 0.32 11.3 0.0 3.3 5 0 0 5 5 5 0 PQQ-like domain Epimerase PF01370.16 EMR69984.1 - 2.6e-14 53.2 0.2 2.6e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR69984.1 - 2.4e-06 27.6 0.1 3.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EMR69984.1 - 4.3e-05 22.8 0.2 6.6e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EMR69984.1 - 0.00043 19.0 0.4 0.00081 18.1 0.1 1.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMR69984.1 - 0.0011 17.8 0.5 0.06 12.2 0.0 2.4 2 1 1 3 3 3 1 Male sterility protein Polysacc_synt_2 PF02719.10 EMR69984.1 - 0.0083 15.0 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EMR69984.1 - 0.015 14.2 0.1 0.023 13.6 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ldh_1_N PF00056.18 EMR69984.1 - 0.02 14.7 0.4 0.059 13.1 0.1 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EMR69984.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF3389 PF11869.3 EMR69984.1 - 0.14 12.0 0.1 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3389) Amidohydro_2 PF04909.9 EMR69985.1 - 3.1e-25 89.2 0.4 3.6e-25 89.0 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase adh_short PF00106.20 EMR69986.1 - 0.0013 18.6 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase COesterase PF00135.23 EMR69987.1 - 9.9e-78 262.1 0.0 3.7e-59 200.8 0.2 2.8 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR69987.1 - 6e-06 25.9 0.3 4.6e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold PsbN PF02468.10 EMR69987.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) ADH_zinc_N PF00107.21 EMR69988.1 - 2.7e-19 69.0 0.7 4.4e-19 68.3 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR69988.1 - 1.6e-11 43.9 1.7 2.2e-11 43.4 0.4 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMR69988.1 - 0.00036 21.4 0.4 0.012 16.5 0.1 2.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EMR69988.1 - 0.0017 17.9 0.5 0.0029 17.1 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain zf-CXXC PF02008.15 EMR69988.1 - 0.012 15.3 2.9 0.021 14.5 2.0 1.3 1 0 0 1 1 1 0 CXXC zinc finger domain IlvN PF07991.7 EMR69988.1 - 0.016 14.6 0.1 0.026 13.8 0.1 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 EMR69988.1 - 0.022 14.5 1.3 0.046 13.5 0.9 1.5 1 0 0 1 1 1 0 ThiF family OapA PF04225.7 EMR69988.1 - 0.036 13.9 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Opacity-associated protein A LysM-like domain 2-Hacid_dh_C PF02826.14 EMR69988.1 - 0.05 12.7 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MTS PF05175.9 EMR69988.1 - 0.11 11.9 1.6 0.39 10.0 1.1 1.8 1 1 0 1 1 1 0 Methyltransferase small domain STAS_2 PF13466.1 EMR69988.1 - 0.88 9.6 5.1 0.65 10.0 0.5 2.8 1 1 1 2 2 2 0 STAS domain Amidohydro_3 PF07969.6 EMR69989.1 - 2.9e-31 109.1 0.0 9.9e-31 107.3 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family FAD_binding_3 PF01494.14 EMR69990.1 - 4.1e-41 141.2 0.0 5.2e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EMR69990.1 - 2.6e-18 66.1 0.0 2.4e-15 56.5 0.0 2.3 1 1 1 2 2 2 2 Phenol hydroxylase, C-terminal dimerisation domain KR PF08659.5 EMR69991.1 - 9.7e-39 132.8 0.4 1.7e-38 132.0 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EMR69991.1 - 3.3e-30 105.1 0.3 1.6e-29 102.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EMR69991.1 - 1.6e-16 60.0 0.0 3.4e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EMR69991.1 - 3.6e-06 27.1 0.2 8.8e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EMR69991.1 - 4.6e-06 26.3 0.1 1.1e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Aldedh PF00171.17 EMR69992.1 - 1.5e-108 363.0 0.1 1.9e-108 362.7 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMR69992.1 - 9.4e-08 31.1 0.0 1.3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) zf-CCCH_2 PF14608.1 EMR69993.1 - 1.4e-06 28.0 10.3 1.4e-06 28.0 7.1 5.3 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 EMR69993.1 - 0.0074 16.3 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) NAD_binding_8 PF13450.1 EMR69994.1 - 3.2e-11 43.1 1.1 9.5e-11 41.5 0.8 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMR69994.1 - 4.6e-11 42.4 3.6 4.8e-05 22.6 0.2 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 EMR69994.1 - 5.5e-10 38.6 6.1 1.8e-07 30.4 0.3 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR69994.1 - 4.8e-06 26.8 0.5 0.004 17.5 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMR69994.1 - 0.026 13.1 0.1 0.05 12.2 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EMR69994.1 - 0.047 13.5 0.6 0.13 12.1 0.4 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR69994.1 - 0.059 12.4 0.1 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Rsbr_N PF08678.5 EMR69994.1 - 0.24 11.2 0.0 0.46 10.3 0.0 1.4 1 0 0 1 1 1 0 Rsbr N terminal ApbA PF02558.11 EMR69994.1 - 0.35 10.3 1.9 0.88 8.9 0.3 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_4 PF01565.18 EMR69995.1 - 2.1e-27 95.2 0.3 3.6e-27 94.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR69995.1 - 0.00021 21.0 0.8 0.00054 19.8 0.6 1.6 1 0 0 1 1 1 1 Berberine and berberine like Raftlin PF15250.1 EMR69995.1 - 0.19 10.2 0.0 0.31 9.5 0.0 1.2 1 0 0 1 1 1 0 Raftlin Pyr_redox_3 PF13738.1 EMR69996.1 - 6.7e-27 94.8 0.0 1e-26 94.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR69996.1 - 5.1e-13 48.8 0.0 1.4e-10 41.0 0.0 2.8 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EMR69996.1 - 1.2e-10 40.2 0.0 1.1e-09 37.0 0.0 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EMR69996.1 - 1.3e-07 31.7 0.0 1.3e-05 25.1 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR69996.1 - 1.3e-07 30.9 0.0 0.00016 20.8 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EMR69996.1 - 2.9e-07 29.7 0.1 1.8e-05 23.8 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EMR69996.1 - 5.6e-07 28.7 0.0 0.00027 19.9 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EMR69996.1 - 4.1e-05 22.6 0.1 0.00098 18.1 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.22 EMR69996.1 - 0.00028 21.2 0.0 0.22 11.9 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR69996.1 - 0.00038 19.4 0.0 0.012 14.4 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.1 EMR69996.1 - 0.0011 18.8 0.1 0.52 10.0 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EMR69996.1 - 0.003 16.2 0.1 1.3 7.5 0.0 3.0 3 0 0 3 3 3 1 Tryptophan halogenase Amino_oxidase PF01593.19 EMR69996.1 - 0.0052 15.9 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 EMR69996.1 - 0.0079 16.2 0.2 1 9.4 0.0 2.9 4 0 0 4 4 3 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EMR69996.1 - 0.086 11.2 0.3 1.1 7.6 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.17 EMR69996.1 - 0.094 11.5 0.1 1.6 7.4 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EMR69996.1 - 0.12 12.1 0.1 0.72 9.5 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EMR69996.1 - 0.18 11.2 0.2 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glyoxalase PF00903.20 EMR69997.1 - 2.4e-40 137.4 0.1 5e-19 68.5 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMR69997.1 - 2.5e-30 105.2 0.2 2.7e-15 56.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EMR69997.1 - 2.8e-16 59.4 0.0 3.7e-07 30.1 0.0 4.0 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EMR69997.1 - 2.2e-06 27.6 0.0 0.054 13.3 0.0 3.3 1 1 1 3 3 3 2 Glyoxalase-like domain 2OG-FeII_Oxy PF03171.15 EMR69998.1 - 2.1e-13 50.4 0.1 3.4e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMR69998.1 - 6.1e-09 36.4 0.0 1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PTPA PF03095.10 EMR69999.1 - 2.3e-85 286.3 0.0 2.9e-85 286.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein tRNA-synt_1b PF00579.20 EMR70000.1 - 2.7e-22 79.2 0.0 9.1e-22 77.5 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Sp38 PF07354.7 EMR70000.1 - 0.028 13.0 0.0 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) Ribosomal_L13e PF01294.13 EMR70001.1 - 1.7e-63 213.3 2.7 2.2e-63 212.9 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Meth_synt_2 PF01717.13 EMR70003.1 - 4.4e-14 52.1 0.0 1.4e-10 40.6 0.0 2.5 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EMR70003.1 - 9.9e-05 21.7 0.0 0.0096 15.2 0.0 2.9 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain Thiolase_N PF00108.18 EMR70004.1 - 3e-75 252.5 0.9 4e-75 252.2 0.6 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMR70004.1 - 1e-40 138.0 0.6 2.3e-40 136.8 0.4 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMR70004.1 - 0.0071 15.8 2.0 0.0071 15.8 1.4 2.1 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EMR70004.1 - 0.1 12.2 1.9 3.7 7.2 0.2 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DNA_methylase PF00145.12 EMR70006.1 - 2.1e-40 138.9 0.0 8.8e-29 100.6 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase LRR_4 PF12799.2 EMR70007.1 - 1.7e-29 100.8 19.3 2.8e-07 30.0 0.7 7.7 4 2 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMR70007.1 - 2e-20 72.2 19.2 0.00028 20.5 0.1 6.7 3 2 4 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 EMR70007.1 - 2.7e-19 66.2 23.1 0.25 11.4 0.1 12.5 12 1 1 13 13 13 6 Leucine Rich Repeat LRR_7 PF13504.1 EMR70007.1 - 2.8e-14 50.7 20.9 0.21 11.9 0.1 10.3 10 0 0 10 10 10 5 Leucine rich repeat LRR_6 PF13516.1 EMR70007.1 - 2.1e-11 42.6 22.9 0.029 14.4 0.5 10.1 9 2 2 11 11 11 3 Leucine Rich repeat PBP1_TM PF14812.1 EMR70008.1 - 0.19 12.0 2.9 0.35 11.1 2.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pribosyltran PF00156.22 EMR70009.1 - 3.1e-09 36.5 0.4 4.3e-08 32.9 0.3 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain RasGAP_C PF03836.10 EMR70009.1 - 0.071 12.8 0.2 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 RasGAP C-terminus Fungal_trans PF04082.13 EMR70010.1 - 2.2e-15 56.2 0.1 3.4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Asp PF00026.18 EMR70011.1 - 1.2e-42 146.3 0.4 1.9e-35 122.6 0.2 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMR70011.1 - 2.8e-06 27.4 0.0 3.4e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMR70011.1 - 0.042 14.3 0.2 0.96 9.9 0.1 2.5 1 1 0 1 1 1 0 Aspartyl protease adh_short PF00106.20 EMR70012.1 - 1.1e-20 74.2 0.3 1.4e-20 73.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR70012.1 - 1.8e-11 44.3 0.0 2.3e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR70012.1 - 3e-09 36.8 0.4 4.4e-09 36.2 0.3 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EMR70012.1 - 0.0016 18.1 0.8 0.0024 17.5 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EMR70012.1 - 0.0024 17.5 3.1 0.0044 16.7 0.6 2.3 3 0 0 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EMR70012.1 - 0.017 14.5 0.1 0.071 12.5 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EMR70012.1 - 0.032 14.3 0.1 0.056 13.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EMR70012.1 - 0.065 13.6 0.4 0.15 12.5 0.3 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent p450 PF00067.17 EMR70013.1 - 7.9e-58 196.0 0.0 1.1e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-CHY PF05495.7 EMR70014.1 - 6.8e-16 58.1 24.3 8e-15 54.7 9.8 3.3 3 0 0 3 3 3 2 CHY zinc finger Mu-like_Com PF10122.4 EMR70014.1 - 2e-05 23.5 0.4 2e-05 23.5 0.3 2.3 2 0 0 2 2 2 1 Mu-like prophage protein Com RWD PF05773.17 EMR70014.1 - 0.0099 15.7 0.1 0.041 13.7 0.0 2.0 2 0 0 2 2 2 1 RWD domain DUF677 PF05055.7 EMR70015.1 - 0.0021 16.8 0.0 0.0026 16.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF677) ING PF12998.2 EMR70015.1 - 0.012 15.8 3.6 0.094 12.9 1.0 2.1 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding OmpH PF03938.9 EMR70015.1 - 0.014 15.3 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) T4SS PF07996.6 EMR70015.1 - 0.079 12.8 0.6 0.15 11.9 0.4 1.5 1 1 1 2 2 2 0 Type IV secretion system proteins TraT PF05818.7 EMR70015.1 - 0.12 11.7 2.0 0.19 11.1 1.4 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Pinin_SDK_memA PF04696.8 EMR70015.1 - 0.29 10.7 8.6 0.4 10.2 6.0 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF2203 PF09969.4 EMR70015.1 - 0.49 10.6 2.7 0.92 9.7 1.9 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Ax_dynein_light PF10211.4 EMR70015.1 - 2 8.2 7.5 2.7 7.7 5.2 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Gly-zipper_OmpA PF13436.1 EMR70015.1 - 6.4 6.4 16.9 27 4.4 11.7 1.9 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Oxidored-like PF09791.4 EMR70016.1 - 8.5e-25 85.9 1.2 8.5e-25 85.9 0.8 2.1 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal DPM3 PF08285.6 EMR70017.1 - 1.2e-33 114.7 0.2 1.4e-33 114.6 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Na_Ca_ex PF01699.19 EMR70018.1 - 4e-41 139.9 28.3 5.6e-24 84.3 8.2 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3295 PF11702.3 EMR70020.1 - 2.5e-134 449.0 30.3 2.9e-134 448.8 21.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) Filament PF00038.16 EMR70021.1 - 5.8e-06 25.9 29.8 5.8e-06 25.9 20.7 6.8 1 1 5 6 6 6 4 Intermediate filament protein Mitofilin PF09731.4 EMR70021.1 - 2.9e-05 22.9 31.0 2.9e-05 22.9 21.5 5.5 2 1 4 6 6 6 1 Mitochondrial inner membrane protein Atg14 PF10186.4 EMR70021.1 - 0.0031 16.5 20.0 0.0031 16.5 13.9 8.1 1 1 6 7 7 7 1 UV radiation resistance protein and autophagy-related subunit 14 Cep57_CLD_2 PF14197.1 EMR70022.1 - 0.028 14.3 1.9 0.028 14.3 1.3 2.6 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF972 PF06156.8 EMR70022.1 - 0.66 10.3 3.9 14 6.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) His_Phos_1 PF00300.17 EMR70023.1 - 1.8e-16 60.6 0.0 3.7e-16 59.5 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Kelch_4 PF13418.1 EMR70024.1 - 8.1e-26 89.5 2.9 1.7e-10 40.4 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EMR70024.1 - 1.4e-23 82.4 12.9 5.6e-07 29.5 0.1 6.7 6 1 1 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EMR70024.1 - 1.2e-18 66.3 6.6 6.9e-06 26.0 0.0 5.7 4 2 1 5 5 5 4 Kelch motif Kelch_5 PF13854.1 EMR70024.1 - 2.4e-18 65.6 3.2 2e-06 27.6 0.0 5.4 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EMR70024.1 - 3.2e-18 64.9 0.1 4.7e-07 29.2 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EMR70024.1 - 2.4e-12 46.1 8.2 2.2e-06 27.1 0.0 5.3 5 1 1 6 6 6 2 Kelch motif CDRN PF05174.7 EMR70026.1 - 0.042 13.3 0.8 7.6 6.0 0.1 2.7 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus HAD_2 PF13419.1 EMR70027.1 - 4.5e-24 85.6 0.0 5.8e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR70027.1 - 0.0037 17.7 0.0 0.013 15.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HTH_CodY PF08222.6 EMR70027.1 - 0.09 12.1 0.0 0.45 9.8 0.0 2.2 2 0 0 2 2 2 0 CodY helix-turn-helix domain Cullin_binding PF03556.10 EMR70028.1 - 3.3e-29 101.4 1.8 4.7e-29 100.8 1.3 1.2 1 0 0 1 1 1 1 Cullin binding SET PF00856.23 EMR70029.1 - 1.2e-22 80.9 0.1 1.2e-21 77.7 0.0 2.4 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 EMR70029.1 - 5.8e-14 52.2 8.6 1.2e-13 51.1 5.9 1.6 1 1 0 1 1 1 1 Pre-SET motif DUF2457 PF10446.4 EMR70029.1 - 2.9 6.5 11.2 5.1 5.7 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SbcCD_C PF13558.1 EMR70030.1 - 3.6e-07 30.0 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EMR70030.1 - 0.0011 18.2 0.2 0.0022 17.2 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Cluap1 PF10234.4 EMR70030.1 - 0.023 13.9 3.9 0.044 12.9 2.7 1.5 1 0 0 1 1 1 0 Clusterin-associated protein-1 TORC_M PF12885.2 EMR70030.1 - 0.064 13.0 3.1 0.044 13.5 0.8 1.6 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain IncA PF04156.9 EMR70030.1 - 0.072 12.6 6.4 0.13 11.8 4.5 1.3 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 EMR70030.1 - 0.087 12.0 8.0 1.7 7.8 3.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding MFS_1 PF07690.11 EMR70031.1 - 1.1e-14 53.9 35.3 1.4e-14 53.6 24.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMR70031.1 - 1.8e-14 53.5 4.0 7.5e-14 51.5 2.7 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 OppC_N PF12911.2 EMR70031.1 - 0.0065 15.8 0.3 0.071 12.4 0.1 2.8 2 0 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C Sugar_tr PF00083.19 EMR70031.1 - 4.4 5.7 27.1 16 3.9 16.3 3.0 1 1 1 2 2 2 0 Sugar (and other) transporter ubiquitin PF00240.18 EMR70032.1 - 0.0014 17.9 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EMR70032.1 - 0.0077 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Nop14 PF04147.7 EMR70032.1 - 0.27 9.1 11.0 0.41 8.5 7.6 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 EMR70032.1 - 1.4 7.2 12.5 0.73 8.1 1.4 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NicO PF03824.11 EMR70032.1 - 5.6 6.1 7.3 8.3 5.6 5.1 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Zip PF02535.17 EMR70032.1 - 7.3 5.4 14.8 0.9 8.4 7.3 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter Nucleoplasmin PF03066.10 EMR70032.1 - 9.8 5.6 15.2 5.4 6.5 1.2 2.3 2 0 0 2 2 2 0 Nucleoplasmin TauD PF02668.11 EMR70033.1 - 1.5e-52 178.8 0.1 1.9e-52 178.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAGK_cat PF00781.19 EMR70036.1 - 1.2e-25 89.3 0.0 2.5e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.7 EMR70037.1 - 2.4e-44 151.3 0.0 4e-38 131.0 0.0 2.0 2 0 0 2 2 2 2 Nucleolar protein,Nop52 DPBB_1 PF03330.13 EMR70039.1 - 8.6e-07 28.8 2.9 1.8e-05 24.6 2.0 2.3 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel AAA_11 PF13086.1 EMR70040.1 - 5.4e-11 42.5 0.1 6.1e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 AAA domain Metallophos PF00149.23 EMR70041.1 - 6.3e-07 28.9 0.4 9.3e-07 28.4 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ank_2 PF12796.2 EMR70043.1 - 1.7e-22 79.5 0.1 1.3e-08 35.1 0.0 4.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMR70043.1 - 9.1e-20 69.4 6.3 0.00075 19.1 0.0 7.6 7 1 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 EMR70043.1 - 1.4e-17 63.6 3.3 1.4e-06 28.6 0.0 5.3 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR70043.1 - 1.8e-14 52.4 5.2 0.00024 21.0 0.0 7.3 8 1 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.1 EMR70043.1 - 5.4e-11 42.3 5.3 0.0071 16.5 0.1 5.2 5 1 0 5 5 5 3 Ankyrin repeats (many copies) HAUS6_N PF14661.1 EMR70044.1 - 4.7e-35 121.1 0.2 4.7e-35 121.1 0.2 1.7 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus GTP_EFTU PF00009.22 EMR70045.1 - 0.05 13.0 0.2 0.46 9.8 0.2 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF4456 PF14644.1 EMR70045.1 - 0.11 11.7 1.2 0.11 11.6 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) MFS_1 PF07690.11 EMR70047.1 - 5.7e-35 120.6 63.6 1.1e-31 109.8 35.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR70048.1 - 2.7e-94 316.3 33.3 3.1e-94 316.0 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR70048.1 - 4.6e-20 71.6 31.2 4.6e-20 71.6 21.6 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Pkinase_Tyr PF07714.12 EMR70049.1 - 7.2e-09 35.0 0.0 0.00021 20.4 0.0 3.3 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.20 EMR70049.1 - 1e-07 31.3 0.0 0.0057 15.8 0.0 3.4 2 1 1 3 3 3 2 Protein kinase domain Fork_head PF00250.13 EMR70050.1 - 6.8e-33 112.5 0.2 1.3e-32 111.6 0.1 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EMR70050.1 - 1.6e-05 24.9 0.0 0.00013 22.0 0.0 2.2 2 0 0 2 2 2 1 FHA domain His_biosynth PF00977.16 EMR70051.1 - 2e-32 112.3 0.0 2.4e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF2985 PF11204.3 EMR70052.1 - 3.4e-35 119.6 0.8 6.1e-35 118.8 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) ADH_zinc_N PF00107.21 EMR70053.1 - 1.2e-19 70.1 0.0 1.8e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR70053.1 - 6.5e-13 48.4 0.0 1.5e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EMR70053.1 - 0.048 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HMG_box PF00505.14 EMR70054.1 - 1.1e-15 57.6 1.6 1.7e-15 56.9 1.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMR70054.1 - 1.5e-05 25.2 0.5 3.2e-05 24.2 0.3 1.6 1 0 0 1 1 1 1 HMG-box domain DUF320 PF03777.8 EMR70054.1 - 0.18 11.6 6.7 4.8 7.0 1.0 3.2 2 1 1 3 3 3 0 Small secreted domain (DUF320) Acetyltransf_3 PF13302.1 EMR70055.1 - 2.6e-13 50.3 0.0 3.5e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR70055.1 - 1.2e-12 47.7 0.3 1.9e-12 47.0 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EMR70055.1 - 1.7e-12 47.5 0.1 2.6e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMR70055.1 - 0.00033 20.5 0.1 0.00049 19.9 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR70055.1 - 0.00052 20.1 0.0 0.00093 19.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR70055.1 - 0.0023 17.6 0.0 0.0062 16.2 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein CLU PF13236.1 EMR70056.1 - 1.6e-79 266.4 0.0 2.4e-79 265.8 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EMR70056.1 - 8.2e-46 156.0 0.5 1.9e-45 154.8 0.0 1.9 2 0 0 2 2 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 EMR70056.1 - 4.8e-24 84.3 0.1 1.1e-23 83.1 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 EMR70056.1 - 1.4e-23 82.5 14.9 5.6e-11 42.2 0.3 3.7 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EMR70056.1 - 3.1e-19 68.2 4.5 0.0003 20.6 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMR70056.1 - 9.8e-08 31.5 4.0 0.024 14.2 0.0 3.6 2 1 2 4 4 4 3 TPR repeat TPR_16 PF13432.1 EMR70056.1 - 0.00011 22.7 4.2 0.9 10.2 1.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF727 PF05303.7 EMR70056.1 - 0.0003 20.5 0.0 0.0011 18.7 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_2 PF07719.12 EMR70056.1 - 0.00078 19.1 8.2 0.35 10.8 0.2 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EMR70056.1 - 0.00099 19.2 0.2 1.3 9.1 0.0 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EMR70056.1 - 0.0035 16.8 0.8 4.3 7.1 0.2 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMR70056.1 - 0.0095 15.7 1.0 0.068 13.0 0.0 2.9 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMR70056.1 - 0.089 12.6 7.9 0.35 10.7 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMR70056.1 - 0.19 11.6 4.7 4.6 7.2 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMR70056.1 - 0.21 11.8 3.1 35 4.9 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMR70056.1 - 1.6 9.3 11.1 1.6 9.3 0.6 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat DDHD PF02862.12 EMR70056.1 - 2.7 7.7 6.8 1.4 8.6 1.8 2.2 2 0 0 2 2 2 0 DDHD domain TPR_14 PF13428.1 EMR70056.1 - 5.1 8.0 10.3 39 5.2 0.1 4.8 2 2 2 4 4 4 0 Tetratricopeptide repeat NPR3 PF03666.8 EMR70056.1 - 7.9 4.8 8.6 7.9 4.8 4.7 1.8 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1682 PF07946.9 EMR70057.1 - 5.2e-104 347.5 2.2 6.1e-104 347.3 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF3864 PF12980.2 EMR70057.1 - 0.014 15.6 0.1 0.46 10.7 0.0 2.8 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) p450 PF00067.17 EMR70057.1 - 2.8 6.3 6.8 5.2 5.4 4.7 1.5 1 1 0 1 1 1 0 Cytochrome P450 DUF3635 PF12330.3 EMR70058.1 - 2.1e-06 27.6 0.1 0.00014 21.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3635) Tubulin_3 PF14881.1 EMR70059.1 - 1.2e-80 269.3 0.0 1.7e-80 268.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EMR70059.1 - 6.4e-43 145.4 0.0 1.1e-42 144.6 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EMR70059.1 - 9.8e-08 32.0 0.0 0.0017 18.2 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain NAD_binding_6 PF08030.7 EMR70060.1 - 9e-21 74.4 0.0 6.9e-12 45.5 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMR70060.1 - 7.5e-17 61.5 11.2 7.5e-17 61.5 7.8 2.1 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EMR70060.1 - 2.8e-16 59.3 0.0 1.1e-15 57.4 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain DUF4131 PF13567.1 EMR70060.1 - 0.59 9.5 6.2 1.8 7.9 4.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4405 PF14358.1 EMR70060.1 - 3.8 7.7 13.3 2.1 8.5 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) SMI1_KNR4 PF09346.5 EMR70061.1 - 0.041 13.9 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) DUF77 PF01910.12 EMR70062.1 - 9.3e-32 108.5 1.2 2.1e-31 107.4 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF77 Catalase PF00199.14 EMR70063.1 - 4.3e-158 525.9 0.1 5.5e-158 525.6 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EMR70063.1 - 5.9e-19 67.6 0.0 1.1e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Fungal_trans PF04082.13 EMR70064.1 - 1.4e-06 27.4 0.2 2.2e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S30 PF04758.9 EMR70066.1 - 0.024 14.3 2.7 0.059 13.1 1.9 1.6 1 0 0 1 1 1 0 Ribosomal protein S30 Viral_env_E26 PF11050.3 EMR70066.1 - 5.1 6.2 5.6 12 4.9 0.3 2.6 2 0 0 2 2 2 0 Virus envelope protein E26 p450 PF00067.17 EMR70067.1 - 1.1e-54 185.7 0.0 2.6e-43 148.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 GPI-anchored PF10342.4 EMR70068.1 - 0.00032 21.1 0.2 0.0018 18.7 0.1 2.0 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family STE PF02200.11 EMR70069.1 - 1.1e-61 205.8 0.5 2e-61 204.9 0.1 1.6 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 EMR70069.1 - 0.00028 21.0 3.8 0.00073 19.7 2.7 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR70069.1 - 0.0014 18.8 2.5 0.0032 17.6 1.7 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger HMG_box PF00505.14 EMR70070.1 - 2.1e-19 69.5 0.4 4.1e-19 68.6 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMR70070.1 - 2.7e-05 24.4 0.1 5.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain EamA PF00892.15 EMR70071.1 - 6.9e-09 35.8 18.6 4.6e-05 23.4 2.1 2.8 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EMR70071.1 - 1.2e-08 34.4 0.1 2.2e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EMR70071.1 - 1.3e-05 24.3 4.3 1.9e-05 23.7 3.0 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EMR70071.1 - 4e-05 23.2 16.6 0.014 15.0 5.9 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family PDR_assoc PF08370.6 EMR70071.1 - 0.01 15.3 1.4 5.8 6.5 0.0 3.4 3 0 0 3 3 3 0 Plant PDR ABC transporter associated TrbC PF04956.8 EMR70071.1 - 0.22 11.5 7.9 0.85 9.6 2.2 3.6 3 0 0 3 3 3 0 TrbC/VIRB2 family DUF2407_C PF13373.1 EMR70071.1 - 0.37 10.7 1.6 0.97 9.3 1.1 1.7 1 0 0 1 1 1 0 DUF2407 C-terminal domain AhpC-TSA_2 PF13911.1 EMR70072.1 - 7.7e-11 41.9 0.1 1.6e-10 40.9 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EMR70072.1 - 1e-05 25.2 0.0 1.9e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMR70072.1 - 3.4e-05 23.4 0.0 0.0082 15.6 0.0 2.1 1 1 0 2 2 2 2 Redoxin GMC_oxred_N PF00732.14 EMR70073.1 - 6.9e-61 205.9 0.0 1.1e-60 205.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR70073.1 - 2e-32 112.4 0.0 4e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMR70073.1 - 9.7e-08 31.2 0.2 0.012 14.5 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMR70073.1 - 4.6e-05 22.5 0.1 7e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMR70073.1 - 0.0062 16.5 0.0 0.024 14.6 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Nucleoplasmin PF03066.10 EMR70073.1 - 0.16 11.5 3.1 7.6 6.0 1.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin CDC37_N PF03234.9 EMR70074.1 - 1.9e-54 184.6 6.3 1.9e-54 184.6 4.3 2.8 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EMR70074.1 - 3.8e-45 153.4 0.2 1.1e-44 152.0 0.0 1.8 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EMR70074.1 - 3.6e-23 81.3 2.2 3.6e-23 81.3 1.5 2.5 2 1 0 2 2 2 1 Cdc37 C terminal domain DUF2762 PF10960.3 EMR70074.1 - 0.056 13.1 0.6 0.056 13.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) SMC_N PF02463.14 EMR70075.1 - 2.4e-56 190.4 33.6 6.1e-56 189.0 23.3 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EMR70075.1 - 3.1e-29 101.3 0.0 1.3e-28 99.3 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EMR70075.1 - 6.1e-16 59.2 1.0 3.9e-07 30.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EMR70075.1 - 1.6e-13 51.4 19.3 1.6e-13 51.4 13.4 7.2 2 2 3 5 5 5 1 AAA domain AAA_15 PF13175.1 EMR70075.1 - 5.3e-07 29.0 32.8 9.2e-07 28.2 3.5 3.6 2 2 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EMR70075.1 - 0.00063 19.2 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 EMR70075.1 - 0.002 17.3 6.3 0.002 17.3 4.3 7.2 3 2 4 7 7 7 2 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 EMR70075.1 - 5.5 5.3 87.8 0.5 8.7 9.2 6.1 3 2 2 6 6 6 0 AAA domain Reo_sigmaC PF04582.7 EMR70075.1 - 8.5 5.4 25.7 1.2 8.2 2.6 5.3 3 2 2 5 5 5 0 Reovirus sigma C capsid protein GPI-anchored PF10342.4 EMR70076.1 - 0.00065 20.1 0.5 0.002 18.5 0.2 2.0 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1900 PF08954.6 EMR70077.1 - 2.2e-48 163.2 0.0 1.2e-47 160.8 0.0 2.1 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) WD40 PF00400.27 EMR70077.1 - 5.3e-26 89.5 5.7 1.3e-07 31.2 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1899 PF08953.6 EMR70077.1 - 3.4e-22 77.8 2.0 1.8e-20 72.3 1.4 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1899) SlyX PF04102.7 EMR70077.1 - 3.9 7.8 6.4 2.3 8.6 1.4 2.3 2 0 0 2 2 2 0 SlyX DUF3535 PF12054.3 EMR70078.1 - 4.1e-144 480.4 0.7 6.2e-143 476.6 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EMR70078.1 - 1.3e-72 244.1 0.0 4.2e-72 242.4 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMR70078.1 - 1.1e-14 54.0 0.0 3.1e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 EMR70078.1 - 1.2e-14 52.9 9.0 0.035 14.1 0.0 8.3 8 0 0 8 8 8 5 HEAT repeat HEAT_EZ PF13513.1 EMR70078.1 - 5.5e-07 29.8 4.9 9.4 6.8 0.0 8.8 9 0 0 9 9 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EMR70078.1 - 2.5e-06 27.7 0.2 0.55 10.6 0.0 4.1 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EMR70078.1 - 4.1e-06 26.9 5.8 0.015 15.5 0.0 6.4 6 2 1 7 7 7 1 HEAT repeats CLASP_N PF12348.3 EMR70078.1 - 0.07 12.4 0.7 11 5.2 0.0 3.3 2 2 1 3 3 3 0 CLASP N terminal Yippee-Mis18 PF03226.9 EMR70079.1 - 6.5e-22 77.3 0.6 7.9e-22 77.1 0.4 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EMR70079.1 - 0.013 15.3 0.5 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I DUF2039 PF10217.4 EMR70079.1 - 0.014 15.4 1.2 0.07 13.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF3268 PF11672.3 EMR70079.1 - 0.015 15.3 0.8 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) HNH_5 PF14279.1 EMR70079.1 - 0.015 15.2 0.3 0.9 9.5 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease zf-CHY PF05495.7 EMR70079.1 - 0.019 15.1 0.9 4.7 7.4 0.1 2.2 2 0 0 2 2 2 0 CHY zinc finger Evr1_Alr PF04777.8 EMR70079.1 - 0.027 14.3 1.2 1.1 9.1 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family DEAD PF00270.24 EMR70080.1 - 6.5e-40 136.3 1.0 1.2e-39 135.5 0.7 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR70080.1 - 3.1e-20 71.8 0.1 1.7e-12 46.9 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EMR70080.1 - 0.00053 19.8 0.5 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EMR70080.1 - 0.0042 16.2 0.2 0.0042 16.2 0.1 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DUF4611 PF15387.1 EMR70080.1 - 0.41 10.8 3.1 0.7 10.0 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SSrecog PF03531.9 EMR70081.1 - 4.1e-74 248.6 0.1 2.5e-73 246.0 0.1 2.0 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EMR70081.1 - 3.6e-25 87.7 0.0 2e-23 82.1 0.0 2.6 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DUF2201_N PF13203.1 EMR70081.1 - 0.014 14.6 0.1 0.014 14.6 0.0 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain AIG2 PF06094.7 EMR70082.1 - 5.4e-07 30.0 0.0 9.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family Abhydrolase_5 PF12695.2 EMR70083.1 - 2.8e-19 69.3 0.3 7.3e-19 67.9 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR70083.1 - 2.7e-10 40.5 7.1 4.5e-09 36.5 4.0 2.4 1 1 2 3 3 3 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR70083.1 - 0.0064 15.7 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EMR70083.1 - 0.018 13.9 0.0 0.047 12.5 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme FSH1 PF03959.8 EMR70083.1 - 0.018 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PAF-AH_p_II PF03403.8 EMR70083.1 - 0.031 12.5 0.0 0.2 9.9 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF1749 PF08538.5 EMR70083.1 - 0.05 12.4 0.0 0.78 8.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) PGAP1 PF07819.8 EMR70083.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 EMR70083.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.2 EMR70084.1 - 6.3e-18 65.4 0.7 7.4e-18 65.2 0.5 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR70084.1 - 8.1e-18 64.5 0.0 1.6e-17 63.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMR70084.1 - 2.6e-10 39.9 1.0 1.3e-09 37.6 0.7 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EMR70084.1 - 2.2e-06 27.3 4.9 4.9e-06 26.1 3.4 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EMR70084.1 - 3.6e-06 26.8 0.0 6.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EMR70084.1 - 1.3e-05 24.5 0.5 6e-05 22.3 0.4 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 EMR70084.1 - 8.1e-05 21.2 3.3 0.00029 19.4 0.8 2.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 EMR70084.1 - 0.00062 19.5 0.1 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase DUF1100 PF06500.6 EMR70084.1 - 0.012 14.2 0.0 0.018 13.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Anillin PF08174.6 EMR70085.1 - 8.5e-32 110.1 0.0 2.4e-31 108.6 0.0 1.8 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EMR70085.1 - 1.3e-08 34.9 0.0 4.3e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 EMR70085.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain E1-E2_ATPase PF00122.15 EMR70086.1 - 1.3e-68 230.5 2.1 1.3e-68 230.5 1.4 2.8 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EMR70086.1 - 4.7e-23 82.7 0.0 2.1e-22 80.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMR70086.1 - 2.8e-13 50.4 0.0 6.1e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMR70086.1 - 2.6e-09 36.4 0.0 7.7e-09 34.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMR70086.1 - 0.0017 17.9 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMR70086.1 - 0.0069 16.3 0.0 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Amidase PF01425.16 EMR70087.1 - 4.2e-82 276.3 0.0 6.4e-82 275.7 0.0 1.3 1 0 0 1 1 1 1 Amidase Methyltransf_31 PF13847.1 EMR70087.1 - 5.5e-13 48.7 0.0 9.3e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR70087.1 - 2.6e-09 37.4 0.0 6.6e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR70087.1 - 1e-08 35.7 0.1 2.4e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR70087.1 - 3.7e-08 33.7 0.0 7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR70087.1 - 1.1e-06 28.9 0.0 2.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR70087.1 - 9.7e-06 25.6 0.1 2.9e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR70087.1 - 1.2e-05 24.7 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EMR70087.1 - 6e-05 22.8 0.0 0.00018 21.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMR70087.1 - 0.00015 21.3 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EMR70087.1 - 0.0012 18.0 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EMR70087.1 - 0.0012 18.5 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMR70087.1 - 0.0013 17.9 0.1 0.0022 17.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 EMR70087.1 - 0.027 13.3 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.15 EMR70087.1 - 0.24 10.3 0.0 0.41 9.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase zf-CCCH PF00642.19 EMR70088.1 - 6e-20 70.4 29.2 8e-07 28.6 0.2 5.4 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EMR70088.1 - 0.022 14.7 0.2 0.022 14.7 0.2 5.6 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type ubiquitin PF00240.18 EMR70089.1 - 9.3e-19 66.5 0.1 1.6e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EMR70089.1 - 1.7e-07 30.8 0.6 3.5e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 EMR70089.1 - 0.00012 21.6 0.0 0.00025 20.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EMR70089.1 - 0.00051 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMR70089.1 - 0.082 13.1 0.3 0.78 10.0 0.2 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain M20_dimer PF07687.9 EMR70090.1 - 6.3e-17 61.3 0.1 1.4e-16 60.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EMR70090.1 - 2.8e-15 56.3 0.2 3.5e-15 56.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 EMR70090.1 - 0.0046 16.7 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Cu_amine_oxid PF01179.15 EMR70091.1 - 3.9e-93 312.4 0.2 5.1e-93 312.0 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EMR70091.1 - 2.5e-07 30.5 0.1 7.4e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Ank_2 PF12796.2 EMR70092.1 - 1.1e-123 403.8 1.2 1.4e-19 70.2 0.0 8.4 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EMR70092.1 - 5.1e-105 338.4 0.8 8.7e-08 31.6 0.0 17.1 17 0 0 17 17 17 14 Ankyrin repeat Ank_3 PF13606.1 EMR70092.1 - 1.6e-77 247.5 0.8 0.00014 21.7 0.0 17.1 17 0 0 17 17 17 13 Ankyrin repeat Ank_4 PF13637.1 EMR70092.1 - 1.3e-75 248.5 8.5 1.1e-09 38.4 0.0 12.7 2 2 12 15 15 15 14 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR70092.1 - 1.3e-65 215.9 6.6 5.4e-09 36.0 0.0 12.9 7 4 6 13 13 13 11 Ankyrin repeats (many copies) NMT1 PF09084.6 EMR70092.1 - 0.034 13.7 0.0 2.2 7.8 0.0 2.7 2 0 0 2 2 2 0 NMT1/THI5 like UDPG_MGDP_dh_C PF03720.10 EMR70092.1 - 0.061 13.4 0.0 59 3.8 0.0 5.5 7 1 0 8 8 8 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF1680 PF07944.7 EMR70093.1 - 7.8e-97 324.7 0.0 1.4e-96 323.8 0.0 1.4 1 1 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Peptidase_S8 PF00082.17 EMR70095.1 - 8.7e-16 57.8 0.5 1.6e-15 57.0 0.3 1.3 1 1 0 1 1 1 1 Subtilase family Glyco_hydro_31 PF01055.21 EMR70096.1 - 4.3e-123 411.3 3.1 1.9e-122 409.3 2.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 PPC PF04151.10 EMR70096.1 - 1 10.4 6.0 16 6.5 0.3 3.9 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain DUF1776 PF08643.5 EMR70097.1 - 2.8e-103 345.1 0.0 1.1e-102 343.2 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Na_H_antiporter PF03553.9 EMR70098.1 - 0.19 10.7 2.3 0.26 10.2 1.5 1.4 1 1 0 1 1 1 0 Na+/H+ antiporter family Lactamase_B PF00753.22 EMR70099.1 - 2.7e-08 33.6 0.1 3.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ADH_zinc_N PF00107.21 EMR70100.1 - 6.5e-34 116.2 0.8 1.2e-33 115.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR70100.1 - 6.7e-12 46.4 0.0 1.4e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR70100.1 - 3e-07 30.1 0.0 8.9e-07 28.6 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EMR70100.1 - 0.0052 16.3 2.1 0.0083 15.7 1.2 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EMR70100.1 - 0.015 15.2 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.1 EMR70100.1 - 0.09 12.7 2.0 0.14 12.1 1.4 1.3 1 0 0 1 1 1 0 NADH(P)-binding HupF_HypC PF01455.13 EMR70100.1 - 0.13 12.2 0.1 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 HupF/HypC family DUF2109 PF09882.4 EMR70101.1 - 0.0062 16.4 7.8 0.015 15.2 0.1 3.3 3 0 0 3 3 3 1 Predicted membrane protein (DUF2109) Calcyon PF06387.6 EMR70101.1 - 0.033 13.5 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) GP41 PF00517.12 EMR70101.1 - 1.1 8.7 5.6 0.17 11.3 0.6 1.9 1 1 1 2 2 2 0 Retroviral envelope protein Phage_holin_2 PF04550.7 EMR70102.1 - 0.0082 16.2 0.6 0.0082 16.2 0.4 1.8 2 1 0 2 2 2 1 Phage holin family 2 PhaG_MnhG_YufB PF03334.9 EMR70102.1 - 1 9.4 6.4 0.47 10.5 0.9 2.2 1 1 1 2 2 2 0 Na+/H+ antiporter subunit Polysacc_synt_C PF14667.1 EMR70102.1 - 1.4 8.6 12.9 0.23 11.2 6.6 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain 2OG-FeII_Oxy_3 PF13640.1 EMR70103.1 - 0.026 15.0 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Malate_synthase PF01274.17 EMR70103.1 - 0.1 10.5 0.1 0.15 10.0 0.1 1.1 1 0 0 1 1 1 0 Malate synthase Transferase PF02458.10 EMR70104.1 - 1.1e-07 30.7 0.0 2.6e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Transferase family Acyl_transf_1 PF00698.16 EMR70105.1 - 9.9e-51 172.9 0.0 4.7e-50 170.7 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EMR70105.1 - 1.1e-25 89.3 0.0 2.3e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EMR70105.1 - 3.3e-25 87.6 2.6 3.3e-25 87.6 1.8 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EMR70105.1 - 1.7e-05 24.5 0.0 6.4e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EMR70105.1 - 0.017 14.2 0.2 3.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Nitronate monooxygenase ketoacyl-synt PF00109.21 EMR70106.1 - 1e-23 84.1 0.2 1e-23 84.1 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EMR70106.1 - 4.2e-16 59.4 0.0 8.3e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 EMR70106.1 - 4.5e-15 55.5 0.1 1.2e-14 54.1 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EMR70106.1 - 2.4e-08 34.0 0.0 2.4e-07 30.7 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR70106.1 - 0.00014 21.5 0.2 0.0017 18.0 0.0 2.7 3 0 0 3 3 3 1 KR domain Shikimate_DH PF01488.15 EMR70106.1 - 0.0013 18.8 0.0 0.0035 17.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EMR70106.1 - 0.003 17.9 0.0 0.014 15.7 0.0 2.2 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EMR70106.1 - 0.047 13.1 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMR70106.1 - 0.14 11.0 0.0 0.31 9.9 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CCDC144C PF14915.1 EMR70106.1 - 0.26 10.1 1.1 0.41 9.5 0.8 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Citrate_synt PF00285.16 EMR70107.1 - 1.2e-94 316.9 0.0 1.5e-94 316.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase ADH_zinc_N_2 PF13602.1 EMR70108.1 - 1e-09 39.3 0.0 6.8e-09 36.6 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMR70108.1 - 1.1e-07 31.4 0.3 2.3e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR70108.1 - 1e-05 25.2 0.2 0.00023 20.9 0.0 2.7 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.21 EMR70109.1 - 3.4e-78 262.6 0.1 5.3e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMR70109.1 - 4.9e-36 123.1 0.1 1.2e-35 121.8 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EMR70109.1 - 0.00025 20.1 0.0 0.00041 19.4 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Glyco_hydro_43 PF04616.9 EMR70110.1 - 1.9e-31 109.2 0.3 2.4e-31 108.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DLH PF01738.13 EMR70111.1 - 4.3e-23 81.7 0.0 5.4e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMR70111.1 - 0.0023 17.7 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR70111.1 - 0.0031 17.0 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR70111.1 - 0.027 14.3 0.1 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Fig1 PF12351.3 EMR70112.1 - 1.3e-18 67.5 0.4 1.9e-17 63.7 0.0 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Glyoxalase PF00903.20 EMR70113.1 - 5e-12 45.9 0.0 1.2e-10 41.4 0.0 2.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EMR70113.1 - 3.2e-10 40.5 0.0 5.1e-09 36.7 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EMR70113.1 - 2e-09 37.4 0.0 3.1e-05 23.9 0.0 2.0 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EMR70113.1 - 0.00024 21.0 0.0 0.00091 19.1 0.0 1.9 2 1 0 2 2 2 1 Glyoxalase-like domain PIG-H PF10181.4 EMR70115.1 - 1.5e-23 82.2 0.0 3.8e-23 80.8 0.0 1.7 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component SSP160 PF06933.6 EMR70115.1 - 0.042 11.8 7.8 0.053 11.5 5.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NPR2 PF06218.6 EMR70115.1 - 0.12 11.0 0.1 0.17 10.5 0.1 1.1 1 0 0 1 1 1 0 Nitrogen permease regulator 2 RNA_pol_Rpb4 PF03874.11 EMR70116.1 - 6.6e-21 74.4 0.0 7.7e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 PseudoU_synth_1 PF01416.15 EMR70117.1 - 1.4e-27 96.1 0.0 3e-20 72.5 0.0 4.1 2 2 0 2 2 2 2 tRNA pseudouridine synthase CBFD_NFYB_HMF PF00808.18 EMR70118.1 - 2.3e-17 62.7 0.2 4.2e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EMR70118.1 - 3.9e-05 23.7 0.0 8.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Spidroin_MaSp PF11260.3 EMR70118.1 - 0.017 15.1 0.1 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 ATP-cone PF03477.11 EMR70118.1 - 0.088 13.2 0.5 0.52 10.7 0.2 2.1 1 1 1 2 2 2 0 ATP cone domain Bromo_TP PF07524.8 EMR70118.1 - 0.12 12.0 0.1 0.37 10.5 0.0 1.7 1 1 1 2 2 2 0 Bromodomain associated Aldedh PF00171.17 EMR70119.1 - 3.4e-137 457.5 0.0 4.2e-137 457.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMR70119.1 - 1.6e-07 30.4 0.0 2.8e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) RRM_1 PF00076.17 EMR70120.1 - 2.4e-07 30.2 0.0 2.8e-05 23.6 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR70120.1 - 1.6e-06 28.0 0.0 6.3e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR70120.1 - 0.00033 20.4 0.0 0.025 14.4 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAR2 PF05282.6 EMR70120.1 - 0.9 8.4 3.8 0.29 10.0 0.1 1.8 2 0 0 2 2 2 0 AAR2 protein TRAP_alpha PF03896.11 EMR70120.1 - 7.3 5.4 9.1 13 4.6 6.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PBD PF00786.23 EMR70121.1 - 0.073 13.4 0.1 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 P21-Rho-binding domain SMK-1 PF04802.10 EMR70123.1 - 1.8e-77 259.2 1.0 4.3e-77 258.0 0.7 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 ADH_zinc_N PF00107.21 EMR70124.1 - 5.5e-17 61.5 0.2 8.2e-17 60.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR70124.1 - 8e-08 33.2 0.1 1.9e-07 32.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR70124.1 - 0.00061 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TPPK_C PF12555.3 EMR70125.1 - 6.5 6.5 1.1 26 4.6 0.1 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal adh_short PF00106.20 EMR70126.1 - 2.8e-20 72.9 0.4 5e-20 72.0 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR70126.1 - 2.4e-16 60.2 0.2 3.2e-16 59.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMR70126.1 - 1.8e-06 28.1 0.2 1.1e-05 25.5 0.1 2.0 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EMR70126.1 - 1.1e-05 25.1 0.1 1.9e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EMR70126.1 - 0.00013 21.3 0.1 0.00019 20.7 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EMR70126.1 - 0.0012 18.3 0.0 0.002 17.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Flagellin_D3 PF08884.6 EMR70126.1 - 0.014 15.5 1.2 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Flagellin D3 domain ADH_zinc_N PF00107.21 EMR70126.1 - 0.023 14.2 0.1 0.051 13.1 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 EMR70126.1 - 0.028 14.0 0.0 0.08 12.5 0.0 1.8 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EMR70126.1 - 0.032 13.9 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RmlD_sub_bind PF04321.12 EMR70126.1 - 0.032 13.1 0.1 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PAE PF03283.8 EMR70126.1 - 0.059 11.9 0.1 0.095 11.3 0.1 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Eno-Rase_NADH_b PF12242.3 EMR70126.1 - 0.17 11.6 0.9 2.3 8.0 0.0 2.7 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_16 PF00722.16 EMR70127.1 - 1.3e-09 37.6 1.2 4e-09 36.0 0.2 2.2 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 BBE PF08031.7 EMR70128.1 - 0.00054 19.8 0.1 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF4111 PF13427.1 EMR70128.1 - 0.099 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) KR PF08659.5 EMR70130.1 - 9.1e-60 201.4 0.0 2.8e-59 199.8 0.0 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR70130.1 - 1.2e-44 152.1 0.5 3.9e-44 150.4 0.0 2.3 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMR70130.1 - 5.3e-39 132.7 0.0 1.3e-38 131.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EMR70130.1 - 1.1e-34 119.9 0.0 3.4e-34 118.3 0.0 1.8 1 1 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 EMR70130.1 - 9.9e-28 97.2 0.0 7.4e-14 51.8 0.0 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMR70130.1 - 1.4e-21 77.1 2.1 3.8e-15 56.0 0.0 3.1 1 1 1 2 2 2 2 Acyl transferase domain ADH_zinc_N PF00107.21 EMR70130.1 - 6.2e-17 61.3 0.0 2.1e-16 59.6 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR70130.1 - 2.8e-08 34.6 0.0 2.5e-07 31.6 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EMR70130.1 - 9.2e-07 29.0 0.1 2.4e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EMR70130.1 - 1.5e-06 28.0 0.0 4.2e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR70130.1 - 3.2e-06 27.5 0.0 1e-05 25.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR70130.1 - 3.8e-05 24.0 0.0 9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR70130.1 - 0.0029 17.1 0.0 0.0073 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR70130.1 - 0.0055 15.8 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EMR70130.1 - 0.027 15.0 0.0 0.09 13.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMR70130.1 - 0.027 14.8 0.0 0.15 12.4 0.0 2.4 2 0 0 2 2 1 0 Methyltransferase domain AMP-binding PF00501.23 EMR70132.1 - 6.4e-258 854.9 0.0 4.9e-83 278.8 0.0 5.1 4 1 0 5 5 5 4 AMP-binding enzyme Condensation PF00668.15 EMR70132.1 - 7e-188 622.7 0.4 5e-57 193.0 0.0 4.3 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 EMR70132.1 - 5.3e-52 173.9 2.9 3.6e-12 46.3 0.1 5.5 5 0 0 5 5 5 4 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EMR70132.1 - 5.3e-45 151.6 0.5 5e-22 78.0 0.0 3.1 2 0 0 2 2 2 2 HxxPF-repeated domain AMP-binding_C PF13193.1 EMR70132.1 - 1.5e-25 89.8 0.2 2.7e-09 37.8 0.0 5.2 5 0 0 5 5 4 4 AMP-binding enzyme C-terminal domain Methyltransf_25 PF13649.1 EMR70132.1 - 4.1e-06 27.0 0.0 1.6e-05 25.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR70132.1 - 0.00011 21.9 0.0 0.0015 18.3 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR70132.1 - 0.001 18.6 0.0 0.0028 17.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR70132.1 - 0.0056 17.1 0.0 0.018 15.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR70132.1 - 0.007 16.3 0.0 0.042 13.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR70132.1 - 0.013 16.0 0.0 0.064 13.8 0.0 2.3 2 0 0 2 2 1 0 Methyltransferase domain FSH1 PF03959.8 EMR70134.1 - 9.8e-20 70.9 0.0 1.2e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EMR70134.1 - 0.0013 18.6 0.0 0.3 10.9 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR70134.1 - 0.011 15.4 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 EMR70134.1 - 0.064 12.6 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain GMC_oxred_N PF00732.14 EMR70135.1 - 1.2e-44 152.6 0.0 2.8e-44 151.4 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR70135.1 - 6.7e-35 120.4 0.0 1.2e-34 119.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lin-8 PF03353.10 EMR70136.1 - 3.8 6.6 8.3 0.16 11.2 1.2 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist zf-CCHC PF00098.18 EMR70138.1 - 0.92 9.5 7.9 0.27 11.2 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EMR70138.1 - 7 6.3 7.1 5.9 6.6 0.3 3.2 3 0 0 3 3 3 0 Zinc knuckle RRM_1 PF00076.17 EMR70140.1 - 1.3e-09 37.5 1.2 0.00072 19.1 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR70140.1 - 4.4e-08 32.9 0.0 2.3e-07 30.6 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NTP_transferase PF00483.18 EMR70143.1 - 6.7e-40 136.9 0.0 7.3e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EMR70143.1 - 2.5e-11 43.9 0.0 2.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.14 EMR70143.1 - 0.0097 15.5 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase IspD PF01128.14 EMR70143.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase BRAP2 PF07576.7 EMR70144.1 - 1e-20 73.3 0.0 1.7e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EMR70144.1 - 3.8e-18 65.3 6.6 9e-18 64.1 4.6 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein SBDS_C PF09377.5 EMR70144.1 - 0.1 12.2 1.1 0.19 11.4 0.8 1.3 1 0 0 1 1 1 0 SBDS protein C-terminal domain DUF4200 PF13863.1 EMR70144.1 - 0.8 9.6 17.1 0.7 9.8 5.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.4 EMR70144.1 - 2.4 7.9 17.5 11 5.9 5.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 EMR70144.1 - 9.2 6.6 7.9 1.7 9.0 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ubiquitin PF00240.18 EMR70145.1 - 4.8e-136 442.3 23.5 1.1e-33 114.4 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EMR70145.1 - 2.2e-78 257.9 21.1 4.3e-19 67.9 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EMR70145.1 - 2.6e-24 85.2 11.1 0.00015 21.9 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EMR70145.1 - 5.2e-22 78.2 1.5 0.00071 19.3 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EMR70145.1 - 5.2e-14 52.0 2.9 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMR70145.1 - 8.1e-14 51.5 2.4 0.13 12.5 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EMR70145.1 - 9.7e-11 41.5 0.0 1.5 8.8 0.0 4.9 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EMR70145.1 - 1.6e-06 27.9 5.8 4.5 7.2 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 EMR70145.1 - 5.3e-06 25.7 0.5 2 7.5 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 EMR70145.1 - 6.8e-05 22.5 5.3 14 5.5 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 EMR70145.1 - 0.00045 18.6 13.5 2.3 6.4 0.2 5.7 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 EMR70145.1 - 0.0011 18.4 0.0 48 3.3 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 EMR70145.1 - 0.0019 18.5 0.6 1e+02 3.3 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF3861 PF12977.2 EMR70145.1 - 0.0055 16.7 5.2 53 4.0 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 EMR70145.1 - 0.023 14.5 14.3 7.9 6.4 0.2 4.4 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 EMR70145.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 EMR70145.1 - 0.037 14.0 7.8 44 4.1 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 EMR70145.1 - 0.071 13.1 12.4 42 4.2 0.1 5.9 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 EMR70145.1 - 0.4 10.6 7.4 1e+02 2.9 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Myosin_N PF02736.14 EMR70145.1 - 1.8 8.2 8.3 1e+02 2.7 0.1 4.7 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain CDC48_2 PF02933.12 EMR70145.1 - 9.3 5.9 12.2 70 3.1 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 Zn_clus PF00172.13 EMR70146.1 - 0.0029 17.4 7.2 0.0057 16.5 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_BMRF2 PF04633.7 EMR70146.1 - 0.26 10.2 0.0 0.39 9.6 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein Carb_anhydrase PF00194.16 EMR70147.1 - 7.7e-18 64.3 0.0 2.9e-17 62.5 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase P_gingi_FimA PF06321.6 EMR70147.1 - 0.041 13.1 0.1 0.062 12.5 0.1 1.2 1 0 0 1 1 1 0 Major fimbrial subunit protein (FimA) MFS_1 PF07690.11 EMR70149.1 - 7.3e-33 113.7 55.2 2.9e-31 108.4 36.9 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Transp_cyt_pur PF02133.10 EMR70150.1 - 3.2e-20 72.0 36.8 2.8e-18 65.7 25.8 2.8 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin tRNA_edit PF04073.10 EMR70150.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain DUF3632 PF12311.3 EMR70151.1 - 9.3e-39 133.1 0.1 1.2e-38 132.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Ribonuclease PF00545.15 EMR70152.1 - 0.00038 20.4 0.2 0.00056 19.9 0.2 1.3 1 0 0 1 1 1 1 ribonuclease TruB-C_2 PF09157.6 EMR70152.1 - 0.087 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal SAD_SRA PF02182.12 EMR70153.1 - 6.8e-25 87.1 0.0 1.6e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 SAD/SRA domain HgmA PF04209.8 EMR70154.1 - 3.8e-136 453.8 0.0 4.4e-136 453.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase ThiF PF00899.16 EMR70155.1 - 2.2e-33 114.9 0.0 4.8e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 ThiF family Ldh_1_N PF00056.18 EMR70155.1 - 0.011 15.5 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EMR70155.1 - 0.013 15.7 0.0 0.045 14.0 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 EMR70155.1 - 0.017 14.5 0.2 0.04 13.3 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EMR70155.1 - 0.035 14.0 0.4 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EMR70155.1 - 0.047 13.0 0.1 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EMR70155.1 - 0.056 13.0 0.2 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EMR70155.1 - 0.13 11.1 4.9 2.2 7.1 0.2 2.7 3 0 0 3 3 3 0 Saccharopine dehydrogenase NUDIX PF00293.23 EMR70156.1 - 2.9e-05 23.7 0.0 5.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF3430 PF11912.3 EMR70157.1 - 0.017 14.9 0.0 0.018 14.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) SRA1 PF07304.6 EMR70158.1 - 2.7e-09 36.9 4.1 7.3e-09 35.5 2.8 1.8 1 1 0 1 1 1 1 Steroid receptor RNA activator (SRA1) AlkA_N PF06029.6 EMR70158.1 - 0.055 13.5 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 AlkA N-terminal domain FAD_binding_3 PF01494.14 EMR70160.1 - 4.2e-21 75.4 0.3 2.2e-20 73.0 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR70160.1 - 1.1e-06 27.8 0.7 0.0029 16.5 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMR70160.1 - 9.1e-05 21.2 0.0 0.13 10.8 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EMR70160.1 - 0.00026 20.9 0.9 0.0012 18.8 0.5 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR70160.1 - 0.00093 19.1 0.2 0.0022 17.8 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR70160.1 - 0.0023 18.2 0.4 0.024 15.0 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EMR70160.1 - 0.0058 16.6 0.2 0.024 14.6 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.7 EMR70160.1 - 0.02 13.8 0.0 0.054 12.4 0.0 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein SE PF08491.5 EMR70160.1 - 0.055 12.2 0.0 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_3 PF01494.14 EMR70161.1 - 4.3e-59 200.3 0.0 1.9e-38 132.4 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.7 EMR70161.1 - 1.2e-37 129.0 0.0 1.8e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 EMR70161.1 - 0.0014 17.7 0.1 0.0028 16.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EMR70161.1 - 0.0016 17.3 0.1 0.0031 16.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR70161.1 - 0.0039 16.1 0.1 0.015 14.2 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EMR70161.1 - 0.0041 15.8 0.0 0.0064 15.1 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EMR70161.1 - 0.015 15.2 0.1 0.039 13.9 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMR70161.1 - 0.03 13.4 0.1 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR70161.1 - 0.078 12.8 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR70161.1 - 0.12 12.8 0.0 0.47 10.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR70162.1 - 8.7e-17 61.6 0.0 1.1e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR70162.1 - 2.2e-07 30.1 0.3 3.6e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EMR70162.1 - 4.2e-07 30.2 0.8 0.0014 18.7 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR70162.1 - 1.1e-05 25.2 1.2 0.014 15.1 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 EMR70162.1 - 0.00031 19.7 1.4 0.021 13.7 0.2 2.2 1 1 1 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EMR70162.1 - 0.0015 17.5 0.7 0.1 11.4 0.2 2.1 1 1 1 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 EMR70162.1 - 0.0023 16.4 0.6 0.02 13.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EMR70162.1 - 0.0028 17.6 0.2 0.0062 16.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR70162.1 - 0.0028 16.6 4.4 0.024 13.5 0.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR70162.1 - 0.0064 15.3 0.1 0.089 11.6 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.14 EMR70162.1 - 0.061 12.3 0.1 0.37 9.8 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EMR70162.1 - 0.096 11.7 0.1 0.22 10.6 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Metallophos PF00149.23 EMR70163.1 - 0.0049 16.2 1.1 0.026 13.9 0.7 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMR70163.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Prenyltrans PF00432.16 EMR70164.1 - 1.7e-58 193.8 6.3 2.1e-12 46.4 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EMR70164.1 - 2.4e-34 118.1 0.0 3.7e-13 49.8 0.0 3.7 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMR70164.1 - 9.6e-09 35.2 0.0 0.00084 19.3 0.0 3.3 1 1 3 4 4 4 2 Prenyltransferase-like MCM PF00493.18 EMR70165.1 - 2.5e-134 447.2 0.0 3.8e-134 446.6 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EMR70165.1 - 9.7e-24 84.1 0.4 3e-23 82.5 0.3 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EMR70165.1 - 1.4e-07 30.8 0.0 1.5e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EMR70165.1 - 4.9e-06 26.3 0.0 1.8e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EMR70165.1 - 0.0024 18.2 1.5 0.0096 16.2 0.6 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EMR70165.1 - 0.022 14.3 0.0 0.08 12.5 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EMR70166.1 - 4.8e-44 149.7 0.0 1.2e-43 148.4 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMR70166.1 - 0.0014 17.7 0.0 0.004 16.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EMR70166.1 - 0.0051 16.8 5.7 0.13 12.2 0.1 3.5 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EMR70166.1 - 0.0056 16.8 0.0 0.15 12.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMR70166.1 - 0.031 15.0 0.0 0.095 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EMR70166.1 - 0.04 13.7 0.1 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.9 EMR70166.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Vps4_C PF09336.5 EMR70166.1 - 0.063 13.1 0.0 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_25 PF13481.1 EMR70166.1 - 0.074 12.4 0.2 4.2 6.7 0.1 2.4 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EMR70166.1 - 0.09 11.9 0.0 0.31 10.1 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EMR70166.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EMR70166.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RRS1 PF04939.7 EMR70167.1 - 1.4e-41 141.7 0.3 2.7e-41 140.8 0.2 1.5 1 1 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Pkinase PF00069.20 EMR70168.1 - 4.2e-56 189.9 0.0 5.5e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR70168.1 - 3.2e-39 134.5 0.0 4.8e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR70168.1 - 2.9e-05 23.2 0.0 0.00017 20.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMR70168.1 - 0.026 13.5 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DAP3 PF10236.4 EMR70169.1 - 9.5e-91 303.9 0.0 1.2e-90 303.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EMR70169.1 - 3.2e-05 24.0 0.1 0.00032 20.7 0.0 2.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 EMR70169.1 - 0.038 13.5 0.3 0.31 10.5 0.2 2.2 1 1 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 EMR70169.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 EMR70169.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 EMR70169.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain HET PF06985.6 EMR70171.1 - 4.7e-12 46.2 0.2 9.3e-10 38.8 0.1 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clr5 PF14420.1 EMR70174.1 - 4.1e-11 42.6 0.0 4.1e-11 42.6 0.0 2.2 3 0 0 3 3 3 1 Clr5 domain FimP PF09766.4 EMR70174.1 - 0.67 8.9 18.9 1.3 8.0 13.1 1.3 1 0 0 1 1 1 0 Fms-interacting protein DDHD PF02862.12 EMR70174.1 - 1.1 9.0 12.1 0.29 10.9 4.2 2.1 2 0 0 2 2 2 0 DDHD domain G0-G1_switch_2 PF15103.1 EMR70174.1 - 1.5 9.1 5.2 0.88 9.8 2.0 1.8 2 0 0 2 2 2 0 G0/G1 switch protein 2 Suf PF05843.9 EMR70174.1 - 1.7 8.2 12.3 0.61 9.7 6.0 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Baculo_PP31 PF05311.6 EMR70174.1 - 3.5 6.8 14.5 0.56 9.4 7.4 1.5 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) GFA PF04828.9 EMR70177.1 - 5.1e-09 35.9 4.6 6.2e-06 26.0 0.1 2.7 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF2072 PF09845.4 EMR70177.1 - 0.13 12.1 5.3 1.4 8.8 0.1 3.0 3 0 0 3 3 3 0 Zn-ribbon containing protein (DUF2072) DUF3636 PF12331.3 EMR70178.1 - 1.1e-32 112.6 0.0 2.8e-32 111.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Mitofilin PF09731.4 EMR70178.1 - 0.28 9.7 9.5 0.42 9.1 6.6 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF812 PF05667.6 EMR70178.1 - 0.52 8.7 8.4 0.86 8.0 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CTP_transf_1 PF01148.15 EMR70179.1 - 2.1e-80 270.1 24.1 2.6e-80 269.8 16.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Sulfate_transp PF00916.15 EMR70180.1 - 1.8e-53 181.3 4.9 1.8e-53 181.3 3.4 1.9 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EMR70180.1 - 8.1e-18 63.8 5.5 8.9e-18 63.7 2.1 2.5 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EMR70180.1 - 3.6e-16 58.6 0.0 7e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EMR70180.1 - 1.1e-07 31.7 0.0 7.6e-07 29.0 0.0 2.4 2 1 0 2 2 2 1 STAS domain CHCH PF06747.8 EMR70181.1 - 5.3e-07 29.3 5.4 8.7e-07 28.6 3.8 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EMR70181.1 - 0.13 12.4 1.5 0.25 11.4 1.1 1.4 1 0 0 1 1 1 0 GCK domain DIOX_N PF14226.1 EMR70182.1 - 3.3e-21 75.9 0.1 2.8e-20 72.9 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMR70182.1 - 7.6e-13 48.5 0.0 1.2e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPK_B1_binding PF04265.9 EMR70183.1 - 1.7e-19 69.2 0.2 3.1e-19 68.4 0.2 1.5 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 EMR70183.1 - 4.2e-16 58.6 0.0 1.7e-09 37.3 0.0 3.1 3 0 0 3 3 3 2 Thiamin pyrophosphokinase, catalytic domain Nucleoplasmin PF03066.10 EMR70183.1 - 0.004 16.6 3.3 0.004 16.6 2.3 2.2 2 0 0 2 2 2 1 Nucleoplasmin CDC45 PF02724.9 EMR70183.1 - 0.67 7.9 9.9 1.4 6.8 1.2 2.1 2 0 0 2 2 2 0 CDC45-like protein Ctr PF04145.10 EMR70183.1 - 1.5 8.8 3.1 12 5.9 0.6 2.3 2 0 0 2 2 2 0 Ctr copper transporter family Eapp_C PF10238.4 EMR70183.1 - 1.6 8.6 8.8 4.1 7.3 0.3 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein DDHD PF02862.12 EMR70183.1 - 3.1 7.5 7.3 8 6.1 0.6 2.1 2 0 0 2 2 2 0 DDHD domain Vfa1 PF08432.5 EMR70183.1 - 6.3 6.7 18.3 0.28 11.1 0.7 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 UCH PF00443.24 EMR70184.1 - 5.1e-54 183.1 0.0 6.2e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMR70184.1 - 2.3e-19 69.9 0.0 5e-19 68.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EMR70184.1 - 2.3e-09 36.5 0.0 4.5e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family ARPC4 PF05856.7 EMR70185.1 - 5e-76 253.8 3.8 5.5e-76 253.6 2.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) F-box PF00646.28 EMR70186.1 - 0.00027 20.4 0.7 0.00027 20.4 0.5 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EMR70186.1 - 0.0019 17.8 0.1 0.0044 16.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like SnoaL PF07366.7 EMR70187.1 - 1.3e-05 24.7 0.0 2.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EMR70187.1 - 0.0003 21.1 0.0 0.00076 19.8 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain Presenilin PF01080.12 EMR70187.1 - 0.13 11.0 0.2 0.19 10.5 0.2 1.1 1 0 0 1 1 1 0 Presenilin Atrophin-1 PF03154.10 EMR70187.1 - 0.71 7.9 12.4 1 7.4 8.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family Trypan_PARP PF05887.6 EMR70187.1 - 5.5 6.8 18.8 9.5 6.0 13.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2052 PF09747.4 EMR70188.1 - 3.5e-30 105.2 0.1 4.5e-30 104.9 0.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) GAT PF03127.9 EMR70190.1 - 3.7e-16 58.9 0.3 8e-16 57.8 0.2 1.5 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 EMR70190.1 - 3e-06 26.9 0.0 6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 VHS domain DUF983 PF06170.7 EMR70191.1 - 0.0072 16.4 0.2 0.032 14.3 0.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF983) Muted PF14942.1 EMR70192.1 - 0.029 14.2 1.4 0.043 13.6 1.0 1.4 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein PP28 PF10252.4 EMR70192.1 - 6.2 6.9 9.5 2.7 8.0 0.6 2.5 2 1 1 3 3 3 0 Casein kinase substrate phosphoprotein PP28 TPR_MLP1_2 PF07926.7 EMR70194.1 - 0.055 13.2 1.0 0.11 12.2 0.1 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein NDT80_PhoG PF05224.7 EMR70195.1 - 4e-48 163.8 0.0 5.3e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Pterin_bind PF00809.17 EMR70197.1 - 5.7e-63 212.0 0.0 9.7e-63 211.3 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EMR70197.1 - 2.1e-40 137.3 0.0 3.2e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.10 EMR70198.1 - 1.8e-70 237.7 0.3 2.5e-70 237.2 0.2 1.2 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EMR70198.1 - 8.3e-11 41.3 0.5 1.8e-10 40.2 0.4 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EMR70198.1 - 2.3e-06 26.7 0.8 3.8e-06 25.9 0.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EMR70198.1 - 0.0024 16.8 0.1 0.0046 15.9 0.1 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 EMR70198.1 - 0.0035 16.3 0.2 0.0059 15.6 0.1 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase MIP PF00230.15 EMR70199.1 - 6.2e-44 150.1 14.3 7.5e-44 149.8 9.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein UPF0016 PF01169.14 EMR70199.1 - 0.037 14.1 0.2 0.037 14.1 0.1 3.3 2 2 3 5 5 5 0 Uncharacterized protein family UPF0016 adh_short_C2 PF13561.1 EMR70200.1 - 1.1e-17 64.6 0.1 2.4e-17 63.5 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR70200.1 - 3.7e-16 59.4 0.5 1.2e-15 57.8 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR70200.1 - 7.1e-06 25.8 0.9 5.2e-05 22.9 0.1 2.1 2 0 0 2 2 2 1 KR domain Glyco_tran_WecB PF03808.8 EMR70200.1 - 0.0032 16.8 0.3 0.084 12.2 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase WecB/TagA/CpsF family DUF1776 PF08643.5 EMR70200.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) YqfQ PF14181.1 EMR70201.1 - 0.48 10.4 18.5 0.4 10.6 3.3 2.3 2 0 0 2 2 2 0 YqfQ-like protein DUF676 PF05057.9 EMR70202.1 - 4.4e-43 147.1 0.3 3.5e-27 95.1 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) PGAP1 PF07819.8 EMR70202.1 - 0.0029 17.2 0.1 0.011 15.3 0.1 1.9 2 0 0 2 2 2 1 PGAP1-like protein Lipase_3 PF01764.20 EMR70202.1 - 0.0049 16.4 0.1 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 Lipase (class 3) ArfGap PF01412.13 EMR70204.1 - 1.4e-35 121.6 1.2 2.7e-35 120.6 0.8 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Aminotran_1_2 PF00155.16 EMR70205.1 - 2e-65 221.1 0.0 2.3e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EMR70205.1 - 3.1e-05 23.2 0.0 4.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EMR70205.1 - 6.5e-05 22.1 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EMR70205.1 - 0.00065 18.0 0.0 0.0011 17.3 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EMR70205.1 - 0.045 12.5 0.0 0.091 11.4 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V Oxidored_q2 PF00420.19 EMR70206.1 - 0.0062 16.0 2.7 0.032 13.8 1.9 2.2 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L WD40 PF00400.27 EMR70207.1 - 7.7e-13 47.7 7.4 5e-05 23.0 0.2 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EMR70207.1 - 0.00017 21.7 0.4 0.36 11.1 0.0 4.4 4 1 1 5 5 5 1 PQQ-like domain PQQ_2 PF13360.1 EMR70207.1 - 0.0008 18.9 0.1 0.0046 16.4 0.1 2.3 1 1 0 1 1 1 1 PQQ-like domain zf-CSL PF05207.8 EMR70209.1 - 0.011 15.2 1.1 2.4 7.7 0.0 2.5 1 1 1 2 2 2 0 CSL zinc finger PS-DH PF14765.1 EMR70211.1 - 5.6e-43 147.2 0.0 9.4e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EMR70211.1 - 4.6e-41 141.2 0.0 1e-40 140.0 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EMR70211.1 - 1.2e-38 132.5 0.4 4.1e-38 130.8 0.3 2.0 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.17 EMR70211.1 - 4.1e-37 126.6 0.1 1.1e-36 125.2 0.0 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EMR70211.1 - 7.9e-32 110.4 0.1 2.4e-31 108.9 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase ketoacyl-synt PF00109.21 EMR70211.1 - 9e-24 84.3 0.0 1.9e-12 47.2 0.0 2.4 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ADH_zinc_N PF00107.21 EMR70211.1 - 9.7e-19 67.2 0.0 6.7e-18 64.4 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMR70211.1 - 3.3e-14 53.1 0.0 9e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR70211.1 - 2.3e-12 46.7 0.0 6.4e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR70211.1 - 5.9e-11 42.3 0.0 2.2e-10 40.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR70211.1 - 6.7e-10 39.5 0.0 2.2e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR70211.1 - 2.7e-09 37.1 0.0 7.8e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EMR70211.1 - 2.8e-09 37.3 0.0 8.5e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EMR70211.1 - 3e-08 34.6 0.0 8.2e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR70211.1 - 6.9e-05 22.5 0.2 0.00015 21.4 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.4 EMR70211.1 - 0.00041 19.8 0.0 0.00086 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EMR70211.1 - 0.001 19.3 0.0 0.0028 17.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR70211.1 - 0.0013 17.9 0.0 0.0048 16.0 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EMR70211.1 - 0.015 14.7 0.0 0.079 12.3 0.0 2.2 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.14 EMR70211.1 - 0.042 13.3 0.0 5.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_L20 PF00453.13 EMR70212.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L20 p450 PF00067.17 EMR70214.1 - 4.8e-43 147.3 0.0 4.2e-41 140.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 EMR70215.1 - 6.4e-35 120.4 25.0 1e-34 119.8 17.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily 2TM PF13239.1 EMR70215.1 - 0.16 12.0 0.2 0.16 12.0 0.2 4.5 5 0 0 5 5 5 0 2TM domain Hex_IIIa PF02455.11 EMR70216.1 - 0.49 9.0 2.3 1.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) TauD PF02668.11 EMR70217.1 - 2.1e-53 181.6 0.1 2.5e-53 181.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family COesterase PF00135.23 EMR70218.1 - 1.8e-91 307.4 0.0 2.2e-91 307.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR70218.1 - 1.9e-08 34.1 0.0 3.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EMR70218.1 - 0.00066 18.9 0.1 0.0011 18.2 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMR70218.1 - 0.0075 16.0 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Alginate_lyase PF05426.7 EMR70220.1 - 0.00088 18.7 3.2 0.0015 17.9 2.2 1.4 1 1 0 1 1 1 1 Alginate lyase Laminin_G_3 PF13385.1 EMR70220.1 - 0.041 14.1 0.1 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_61 PF03443.9 EMR70221.1 - 8.1e-72 241.5 0.0 9.2e-72 241.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Acetyltransf_1 PF00583.19 EMR70222.1 - 6.8e-08 32.4 0.0 1.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR70222.1 - 3.9e-06 26.9 0.0 6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR70222.1 - 9.8e-06 25.6 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR70222.1 - 0.0033 17.2 0.0 0.0078 16.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR70222.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein HET PF06985.6 EMR70223.1 - 8.7e-35 119.9 0.0 1.4e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aminotran_1_2 PF00155.16 EMR70224.1 - 5e-25 88.2 0.0 1.4e-24 86.7 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMR70224.1 - 0.0011 17.3 0.0 0.0017 16.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EMR70224.1 - 0.0084 15.1 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.15 EMR70224.1 - 0.18 10.3 0.0 0.61 8.5 0.0 1.8 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Glyco_hydr_30_2 PF14587.1 EMR70225.1 - 2.9e-19 69.2 9.6 6.1e-19 68.1 6.7 1.5 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Melibiase PF02065.13 EMR70226.1 - 4.8e-16 58.4 0.1 1.9e-09 36.7 0.0 2.0 2 0 0 2 2 2 2 Melibiase Glyco_hydro_88 PF07470.8 EMR70227.1 - 1.9e-15 56.7 0.5 2.6e-15 56.3 0.4 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Trypan_PARP PF05887.6 EMR70228.1 - 0.75 9.6 11.6 1.2 8.9 8.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ADH_zinc_N PF00107.21 EMR70229.1 - 2.3e-14 53.0 0.0 4.4e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR70229.1 - 2.8e-05 23.8 0.5 9.1e-05 22.1 0.3 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Dabb PF07876.7 EMR70230.1 - 5e-07 30.0 0.0 6.7e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Abhydrolase_3 PF07859.8 EMR70231.1 - 2.6e-23 82.7 0.0 3.3e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EMR70231.1 - 2.1e-06 26.6 0.0 7.3e-06 24.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EMR70231.1 - 0.00079 19.2 0.1 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EMR70231.1 - 0.018 13.7 0.1 0.2 10.3 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family FSH1 PF03959.8 EMR70231.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Hexokinase_1 PF00349.16 EMR70232.1 - 0.15 11.3 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Hexokinase Cellulase PF00150.13 EMR70233.1 - 9.5e-20 70.9 0.9 1.3e-19 70.4 0.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EMR70233.1 - 1.4e-06 28.6 0.0 3.1e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 EMR70233.1 - 6.5e-06 25.2 0.0 1.7e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 EMR70233.1 - 0.0015 17.7 0.1 0.0053 15.9 0.0 1.8 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_10 PF00331.15 EMR70233.1 - 0.013 14.5 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 DUF4434 PF14488.1 EMR70233.1 - 0.023 14.4 0.1 8.4 6.1 0.0 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4434) Abhydrolase_6 PF12697.2 EMR70234.1 - 4.6e-07 29.9 0.3 1e-06 28.8 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EMR70234.1 - 0.00077 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 EMR70234.1 - 0.012 15.1 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 EMR70234.1 - 0.024 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.7 EMR70234.1 - 0.039 13.4 0.0 0.098 12.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase PGAP1 PF07819.8 EMR70234.1 - 0.051 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein adh_short PF00106.20 EMR70235.1 - 1.5e-31 109.5 4.3 2.2e-31 109.0 3.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR70235.1 - 9.3e-16 58.3 0.1 1.4e-15 57.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR70235.1 - 2.8e-14 53.1 5.5 6.3e-14 52.0 3.8 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR70235.1 - 8.6e-06 25.3 0.6 1.9e-05 24.2 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMR70235.1 - 0.0002 21.0 0.5 0.00043 20.0 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EMR70235.1 - 0.0032 17.5 2.1 0.0078 16.2 1.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 EMR70235.1 - 0.024 13.7 0.0 0.088 11.9 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EMR70235.1 - 0.027 13.5 0.1 0.053 12.5 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 EMR70235.1 - 0.028 14.6 0.2 0.053 13.7 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 EMR70235.1 - 0.03 13.7 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.8 EMR70235.1 - 0.034 13.3 0.3 0.069 12.3 0.2 1.6 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.13 EMR70235.1 - 0.061 12.9 0.5 0.14 11.7 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SAP18 PF06487.7 EMR70237.1 - 1.6e-24 86.0 0.0 2.1e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) RPN7 PF10602.4 EMR70238.1 - 8.6e-40 135.9 0.0 2.1e-39 134.7 0.0 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 EMR70238.1 - 5.8e-15 55.4 0.0 1.3e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF357 PF04010.8 EMR70238.1 - 0.0082 15.8 0.1 4.7 6.9 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF357) Toxin_56 PF15534.1 EMR70238.1 - 0.011 16.2 0.1 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 Putative toxin 56 Acetyltransf_1 PF00583.19 EMR70240.1 - 3.1e-11 43.1 0.1 5.2e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR70240.1 - 2.8e-09 37.0 0.0 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR70240.1 - 0.0064 16.3 0.0 0.0075 16.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NDUF_B4 PF07225.7 EMR70242.1 - 0.013 15.2 0.1 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) MscS_TM PF12794.2 EMR70242.1 - 0.11 11.1 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Lipase_3 PF01764.20 EMR70243.1 - 2.3e-16 59.6 0.0 2.6e-12 46.5 0.0 2.3 1 1 1 2 2 2 2 Lipase (class 3) Abhydrolase_6 PF12697.2 EMR70243.1 - 0.0056 16.5 0.3 0.0095 15.8 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR70243.1 - 0.066 12.9 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family 2OG-FeII_Oxy PF03171.15 EMR70245.1 - 9.1e-06 25.8 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NUDIX PF00293.23 EMR70246.1 - 2e-21 76.0 0.4 2.3e-21 75.8 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EMR70246.1 - 0.00055 19.3 0.0 0.00088 18.6 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain Prp18 PF02840.10 EMR70247.1 - 2.9e-50 169.8 0.1 2.9e-50 169.8 0.0 2.3 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EMR70247.1 - 1.4e-11 43.4 5.7 1.4e-11 43.4 4.0 2.9 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CDC27 PF09507.5 EMR70247.1 - 0.15 11.2 18.0 0.018 14.2 8.4 1.9 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Ycf1 PF05758.7 EMR70247.1 - 0.48 8.0 4.0 0.58 7.8 2.8 1.1 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 EMR70247.1 - 1.5 8.1 15.4 0.21 11.0 6.2 2.1 2 0 0 2 2 2 0 Spore coat protein CotO DAO PF01266.19 EMR70248.1 - 4.6e-37 127.7 0.1 6.2e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR70248.1 - 0.016 15.2 0.0 0.049 13.6 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EMR70248.1 - 0.018 14.7 1.2 2 8.1 0.0 3.3 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EMR70248.1 - 0.071 12.0 0.0 0.51 9.2 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein TF_Zn_Ribbon PF08271.7 EMR70250.1 - 1.6 8.0 5.9 12 5.2 0.2 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding GST_N PF02798.15 EMR70251.1 - 3e-09 36.9 0.0 5.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMR70251.1 - 5.2e-07 29.8 0.0 8.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMR70251.1 - 7e-07 29.1 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR70251.1 - 2e-05 24.4 0.0 4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR70251.1 - 5.1e-05 23.6 0.0 8.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMR70251.1 - 0.00049 19.9 0.1 0.0018 18.1 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PepSY_TM_3 PF13706.1 EMR70251.1 - 0.11 11.8 0.5 0.21 11.0 0.3 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix Abhydrolase_6 PF12697.2 EMR70252.1 - 4e-09 36.6 4.1 4e-09 36.6 2.9 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR70252.1 - 9.2e-09 35.1 0.3 1.7e-08 34.3 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EMR70252.1 - 6.4e-05 21.7 0.1 0.0019 16.8 0.1 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.13 EMR70252.1 - 8.3e-05 22.1 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EMR70252.1 - 0.002 17.3 0.1 0.0065 15.7 0.0 1.7 1 1 1 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.15 EMR70252.1 - 0.002 17.5 0.0 0.0053 16.2 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 EMR70252.1 - 0.009 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.9 EMR70252.1 - 0.058 12.5 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Abhydrolase_2 PF02230.11 EMR70252.1 - 0.11 11.9 0.0 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Sugar_tr PF00083.19 EMR70253.1 - 2.6e-30 105.4 8.2 1.4e-21 76.5 0.1 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR70253.1 - 8e-05 21.5 2.1 0.00022 20.0 1.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Pam17 PF08566.5 EMR70253.1 - 0.0022 17.7 1.8 0.047 13.3 0.2 2.3 1 1 1 2 2 2 2 Mitochondrial import protein Pam17 IBR PF01485.16 EMR70255.1 - 8.1e-14 51.2 16.1 2.4e-13 49.7 2.0 3.4 3 0 0 3 3 3 1 IBR domain Vmethyltransf PF01660.12 EMR70255.1 - 0.11 11.1 0.1 0.19 10.3 0.1 1.4 1 0 0 1 1 1 0 Viral methyltransferase C1_4 PF07975.7 EMR70255.1 - 1.3 9.1 16.6 2 8.4 3.9 3.2 3 0 0 3 3 3 0 TFIIH C1-like domain DUF3523 PF12037.3 EMR70255.1 - 3.7 6.4 33.7 5.3 5.9 23.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) BNIP2 PF12496.3 EMR70255.1 - 4.5 7.4 0.0 4.5 7.4 0.0 2.6 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 zf-AN1 PF01428.11 EMR70255.1 - 5.6 6.9 12.1 0.62 9.9 1.8 3.0 3 0 0 3 3 3 0 AN1-like Zinc finger zf-CHY PF05495.7 EMR70255.1 - 6.8 6.9 13.9 0.32 11.1 0.8 3.0 3 0 0 3 3 3 0 CHY zinc finger zinc_ribbon_5 PF13719.1 EMR70255.1 - 8.2 6.1 12.1 0.52 9.9 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain IncFII_repA PF02387.10 EMR70255.1 - 8.3 5.4 14.9 12 4.9 10.3 1.2 1 0 0 1 1 1 0 IncFII RepA protein family Pyridox_ox_2 PF12900.2 EMR70256.1 - 7.2e-35 119.8 0.0 9.7e-35 119.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase p450 PF00067.17 EMR70257.1 - 2e-64 217.8 0.0 2.6e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MoaE PF02391.12 EMR70257.1 - 0.09 12.5 0.0 0.8 9.5 0.0 2.1 2 0 0 2 2 2 0 MoaE protein Amidase PF01425.16 EMR70258.1 - 4.8e-84 282.7 0.1 8.3e-81 272.0 0.1 2.1 2 0 0 2 2 2 2 Amidase HSP70 PF00012.15 EMR70259.1 - 2.4e-15 55.4 0.0 9.3e-15 53.5 0.0 1.7 2 0 0 2 2 2 1 Hsp70 protein DUF2191 PF09957.4 EMR70259.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2191) FGGY_C PF02782.11 EMR70259.1 - 0.11 12.0 0.0 0.31 10.6 0.0 1.7 1 1 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Pkinase PF00069.20 EMR70261.1 - 0.018 14.2 0.0 3.9 6.5 0.0 2.4 1 1 2 3 3 3 0 Protein kinase domain FAM110_N PF14161.1 EMR70261.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Centrosome-associated N terminus Aldo_ket_red PF00248.16 EMR70263.1 - 1.6e-51 174.8 0.0 1.8e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AdoHcyase PF05221.12 EMR70263.1 - 0.025 13.5 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase Methyltransf_16 PF10294.4 EMR70264.1 - 5.1e-14 52.1 0.0 9.1e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EMR70264.1 - 2.1e-06 28.2 0.0 4.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR70264.1 - 0.0015 17.9 0.0 0.03 13.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EMR70264.1 - 0.006 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR70264.1 - 0.012 16.0 0.0 0.062 13.7 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EMR70264.1 - 0.092 12.3 0.0 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMR70264.1 - 0.093 13.2 0.0 0.47 10.9 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EMR70264.1 - 0.17 11.9 1.5 0.41 10.6 1.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Spermine_synth PF01564.12 EMR70265.1 - 1.7e-07 30.4 0.0 2.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 EMR70265.1 - 2.4e-06 27.5 0.3 1.1e-05 25.3 0.0 2.2 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR70265.1 - 0.0038 17.7 0.0 0.044 14.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_S41 PF03572.13 EMR70266.1 - 1.5e-06 27.7 0.0 1.1e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 Peptidase family S41 Glyco_hydro_47 PF01532.15 EMR70267.1 - 7.7e-114 380.8 0.0 1e-113 380.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SART-1 PF03343.8 EMR70268.1 - 0.00029 19.3 7.2 0.00036 19.0 5.0 1.1 1 0 0 1 1 1 1 SART-1 family HHH_5 PF14520.1 EMR70268.1 - 0.0023 18.0 0.0 0.0058 16.7 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Stathmin PF00836.14 EMR70268.1 - 0.01 15.4 2.4 0.018 14.7 1.7 1.4 1 0 0 1 1 1 0 Stathmin family PRP1_N PF06424.7 EMR70268.1 - 0.11 12.8 4.7 0.15 12.3 3.3 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal RR_TM4-6 PF06459.7 EMR70268.1 - 3.2 7.5 10.0 4.2 7.1 6.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SMP PF04927.7 EMR70270.1 - 4e-06 26.6 9.0 0.064 13.2 0.1 4.1 2 2 2 4 4 4 4 Seed maturation protein AAA_13 PF13166.1 EMR70271.1 - 0.00084 17.9 66.3 0.0024 16.4 15.4 3.1 1 1 2 3 3 3 3 AAA domain TMF_DNA_bd PF12329.3 EMR70271.1 - 0.0045 16.7 6.7 0.0045 16.7 4.7 8.5 5 2 4 9 9 9 2 TATA element modulatory factor 1 DNA binding Es2 PF09751.4 EMR70272.1 - 2.8e-104 349.8 5.1 3.5e-104 349.5 3.5 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 YajC PF02699.10 EMR70272.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit UCH PF00443.24 EMR70273.1 - 3.1e-22 78.9 0.0 4.5e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EMR70273.1 - 1.1e-12 47.8 0.2 2e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Rxt3 PF08642.5 EMR70275.1 - 9.2e-32 109.6 0.5 2.4e-31 108.3 0.0 1.9 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EMR70275.1 - 3.1e-08 33.4 0.0 2.3e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 LCCL domain ADH_zinc_N PF00107.21 EMR70277.1 - 6e-10 38.7 0.4 9.6e-10 38.1 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR70277.1 - 5.1e-09 35.8 0.0 1.1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.3 EMR70277.1 - 0.007 16.1 0.2 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4231 PF14015.1 EMR70278.1 - 0.00035 20.5 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) DUF3824 PF12868.2 EMR70279.1 - 3.3e-06 28.0 2.0 4.9e-06 27.5 1.4 1.3 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) DUF2648 PF10855.3 EMR70279.1 - 0.0066 15.8 0.6 0.0097 15.3 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2648) ATP-synt_E PF05680.7 EMR70279.1 - 0.039 13.8 2.4 0.062 13.2 1.6 1.5 1 1 0 1 1 1 0 ATP synthase E chain DUF2956 PF11169.3 EMR70279.1 - 0.057 13.3 0.3 0.07 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) RTA1 PF04479.8 EMR70280.1 - 2.5e-44 151.4 0.1 3.4e-44 151.0 0.1 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF368 PF04018.8 EMR70280.1 - 5.8 6.0 8.7 0.5 9.4 1.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF368) VIT1 PF01988.14 EMR70280.1 - 7.9 5.9 8.0 4.5 6.6 1.1 2.5 3 0 0 3 3 3 0 VIT family Adaptin_N PF01602.15 EMR70281.1 - 1.8e-94 317.0 12.5 3.2e-94 316.1 8.6 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 EMR70281.1 - 2.1e-63 212.1 1.1 5e-63 210.9 0.8 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 EMR70281.1 - 7.1e-63 210.1 0.0 2.1e-62 208.6 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 EMR70281.1 - 1.6e-10 41.0 11.9 1.2e-07 31.8 0.1 4.3 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.2 EMR70281.1 - 4.1e-05 23.4 9.2 0.00048 20.0 0.0 3.8 2 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EMR70281.1 - 0.00062 19.6 0.4 0.17 12.0 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EMR70281.1 - 0.022 15.2 6.1 2 9.0 0.0 4.7 4 1 1 5 5 5 0 HEAT-like repeat GMC_oxred_C PF05199.8 EMR70282.1 - 2.4e-29 102.4 0.0 4.2e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR70282.1 - 1.9e-16 60.1 0.0 2.7e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Myb_DNA-bind_2 PF08914.6 EMR70282.1 - 0.073 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Rap1 Myb domain Pkinase PF00069.20 EMR70283.1 - 7.5e-57 192.4 0.1 1.2e-55 188.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR70283.1 - 3.5e-26 91.8 0.2 6.8e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMR70283.1 - 8.6e-05 21.6 0.3 0.00019 20.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMR70283.1 - 0.00055 19.0 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 EMR70283.1 - 0.003 18.0 0.1 0.0067 16.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 EMR70283.1 - 0.0034 17.1 2.0 0.023 14.4 0.1 2.5 2 1 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EMR70283.1 - 0.04 12.7 0.1 0.062 12.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 EMR70283.1 - 0.069 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 EMR70283.1 - 0.42 9.9 3.5 0.28 10.5 0.1 2.0 2 0 0 2 2 2 0 RIO1 family Cyclin PF08613.6 EMR70284.1 - 2.9e-11 43.9 0.0 5.2e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin HTH_29 PF13551.1 EMR70284.1 - 0.029 14.5 1.8 0.076 13.1 1.2 1.7 1 0 0 1 1 1 0 Winged helix-turn helix Cyclin_N PF00134.18 EMR70284.1 - 0.034 13.7 0.2 0.087 12.3 0.0 1.8 2 0 0 2 2 2 0 Cyclin, N-terminal domain APC_CDC26 PF10471.4 EMR70284.1 - 2.1 9.1 8.0 0.77 10.5 3.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Nefa_Nip30_N PF10187.4 EMR70285.1 - 5.7e-23 81.0 7.0 5.7e-23 81.0 4.9 2.7 2 2 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Med3 PF11593.3 EMR70285.1 - 0.96 8.6 10.8 1.6 7.9 7.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pec_lyase_C PF00544.14 EMR70286.1 - 4.7e-25 88.2 0.5 6.4e-25 87.7 0.4 1.1 1 0 0 1 1 1 1 Pectate lyase Tim54 PF11711.3 EMR70287.1 - 2.6e-113 378.4 0.4 5.2e-113 377.5 0.3 1.5 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 zf-met PF12874.2 EMR70288.1 - 8.4e-06 25.8 1.0 1.5e-05 25.0 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EMR70288.1 - 0.058 12.6 0.9 0.1 11.9 0.6 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like GBP PF02263.14 EMR70289.1 - 0.19 10.7 0.1 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain NAD_binding_8 PF13450.1 EMR70292.1 - 3e-10 39.9 0.0 8.5e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMR70292.1 - 6.1e-09 35.4 0.1 5.5e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 EMR70292.1 - 2.5e-06 26.6 0.8 2.5e-06 26.6 0.6 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR70292.1 - 4.2e-06 26.9 0.2 0.0017 18.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR70292.1 - 2.2e-05 23.4 1.8 2.2e-05 23.4 1.2 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EMR70292.1 - 2.3e-05 24.3 0.4 0.00091 19.1 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMR70292.1 - 9.5e-05 21.6 2.1 0.018 14.1 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EMR70292.1 - 0.0002 20.5 0.9 0.00044 19.4 0.6 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EMR70292.1 - 0.00066 18.2 1.8 0.00066 18.2 1.2 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EMR70292.1 - 0.0018 17.2 0.7 0.0029 16.5 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EMR70292.1 - 0.0089 16.4 2.6 0.035 14.5 0.7 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR70292.1 - 0.021 13.7 0.9 0.028 13.3 0.2 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EMR70292.1 - 0.035 12.7 1.5 0.054 12.1 1.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.1 EMR70292.1 - 0.042 12.7 0.2 0.97 8.2 0.1 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) IlvN PF07991.7 EMR70292.1 - 0.059 12.7 0.1 0.47 9.8 0.1 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 EMR70292.1 - 0.075 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Pec_lyase_C PF00544.14 EMR70293.1 - 1.2e-08 34.6 0.8 1.6e-08 34.3 0.5 1.2 1 0 0 1 1 1 1 Pectate lyase Pro_CA PF00484.14 EMR70294.1 - 1.9e-18 66.9 0.0 1.8e-09 37.8 0.1 2.1 1 1 1 2 2 2 2 Carbonic anhydrase Abhydrolase_6 PF12697.2 EMR70295.1 - 5.5e-35 121.2 2.2 6.9e-35 120.9 1.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR70295.1 - 2e-20 73.3 0.1 4.4e-16 59.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR70295.1 - 3.7e-16 59.2 0.0 6.2e-16 58.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMR70295.1 - 3.7e-05 23.5 0.0 7.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EMR70295.1 - 0.00043 18.8 0.0 0.00084 17.9 0.0 1.4 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.8 EMR70295.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_3 PF07859.8 EMR70295.1 - 0.056 13.0 0.1 0.13 11.8 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 EMR70295.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.2 EMR70295.1 - 0.15 10.9 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.8 EMR70295.1 - 0.15 11.6 0.3 0.24 10.9 0.2 1.2 1 0 0 1 1 1 0 PGAP1-like protein Adaptin_N PF01602.15 EMR70296.1 - 2.9e-47 161.1 0.0 1.7e-32 112.4 0.0 2.9 2 1 1 3 3 3 3 Adaptin N terminal region HEAT_2 PF13646.1 EMR70296.1 - 0.018 15.2 0.6 0.3 11.4 0.0 2.9 2 1 1 3 3 3 0 HEAT repeats HEAT PF02985.17 EMR70296.1 - 0.068 13.2 0.0 2.8 8.2 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat Sugar_tr PF00083.19 EMR70297.1 - 2.1e-87 293.6 26.9 2.4e-87 293.3 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR70297.1 - 2.7e-14 52.6 38.3 5.8e-10 38.4 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.19 EMR70298.1 - 2.7e-45 154.8 8.2 3.9e-44 151.0 5.7 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR70298.1 - 3.8e-06 27.2 0.2 0.01 16.2 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR70298.1 - 1.4e-05 24.9 1.1 3.9e-05 23.6 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR70298.1 - 0.00023 21.1 0.4 0.17 11.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR70298.1 - 0.0031 17.3 0.2 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding PHY PF00360.15 EMR70298.1 - 0.032 13.3 0.1 0.08 12.0 0.1 1.6 1 0 0 1 1 1 0 Phytochrome region Trp_halogenase PF04820.9 EMR70298.1 - 0.082 11.5 0.1 0.3 9.6 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase DUF3644 PF12358.3 EMR70298.1 - 0.13 12.5 0.6 0.29 11.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3644) Strep_67kDa_ant PF06100.6 EMR70298.1 - 0.37 9.0 0.7 0.45 8.8 0.0 1.4 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Ribosomal_60s PF00428.14 EMR70298.1 - 0.53 10.7 11.2 1.4 9.4 0.6 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Amastin PF07344.6 EMR70299.1 - 4.3 6.9 9.9 4.6 6.8 0.2 2.5 1 1 1 2 2 2 0 Amastin surface glycoprotein MAM PF00629.18 EMR70300.1 - 0.00047 19.9 0.0 0.00062 19.5 0.0 1.1 1 0 0 1 1 1 1 MAM domain CBM_4_9 PF02018.12 EMR70300.1 - 0.00052 20.0 0.1 0.0012 18.8 0.0 1.6 1 1 0 1 1 1 1 Carbohydrate binding domain DIM PF08194.7 EMR70300.1 - 0.74 9.8 2.9 1.6 8.7 0.2 2.5 2 0 0 2 2 2 0 DIM protein HA2 PF04408.18 EMR70301.1 - 1.8e-19 69.6 0.0 4.8e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMR70301.1 - 1.6e-13 50.3 0.0 5.2e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EMR70301.1 - 4.6e-11 42.5 0.0 1.1e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EMR70301.1 - 1.5e-08 34.3 0.2 2.2e-07 30.5 0.1 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMR70301.1 - 0.0016 18.6 0.3 0.0066 16.5 0.0 2.1 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EMR70301.1 - 0.011 14.6 0.0 0.027 13.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.10 EMR70301.1 - 0.014 15.2 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit KaiC PF06745.8 EMR70301.1 - 0.021 13.9 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 EMR70301.1 - 0.041 13.1 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 EMR70301.1 - 0.051 13.9 0.0 0.051 13.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EMR70301.1 - 0.051 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EMR70301.1 - 0.055 13.2 0.0 0.53 10.0 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain CDC45 PF02724.9 EMR70301.1 - 1.3 7.0 11.3 3 5.7 7.8 1.5 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.9 EMR70302.1 - 1.1e-23 83.5 0.0 1.1e-23 83.5 0.0 3.0 4 0 0 4 4 4 1 RNA polymerase III RPC4 STAG PF08514.6 EMR70303.1 - 6.8e-28 96.7 0.1 2.2e-27 95.1 0.0 1.9 1 0 0 1 1 1 1 STAG domain CLASP_N PF12348.3 EMR70303.1 - 0.0017 17.7 0.0 0.0037 16.6 0.0 1.5 1 0 0 1 1 1 1 CLASP N terminal Cnd1 PF12717.2 EMR70303.1 - 0.05 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 FAD_binding_3 PF01494.14 EMR70304.1 - 1.5e-09 37.4 0.0 7.1e-09 35.1 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMR70304.1 - 3.1e-06 27.1 0.0 2.1e-05 24.4 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR70304.1 - 0.0026 16.7 0.1 0.03 13.2 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR70304.1 - 0.0092 16.3 0.0 0.062 13.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR70304.1 - 0.022 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family AXH PF08517.7 EMR70304.1 - 0.031 14.4 0.0 0.089 12.9 0.0 1.7 1 0 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) FAD_binding_2 PF00890.19 EMR70304.1 - 0.13 11.1 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EMR70304.1 - 0.13 10.6 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EMR70304.1 - 0.14 11.9 0.3 0.38 10.5 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EMR70304.1 - 0.15 10.9 0.0 0.56 9.0 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMR70304.1 - 0.19 11.7 0.0 0.33 10.9 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BUD22 PF09073.5 EMR70304.1 - 3.5 6.6 7.4 4.8 6.1 5.1 1.1 1 0 0 1 1 1 0 BUD22 Med6 PF04934.9 EMR70305.1 - 1.3e-39 134.9 0.0 1.8e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component CMV_1a PF12467.3 EMR70305.1 - 0.15 12.4 0.1 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Methyltransf_2 PF00891.13 EMR70306.1 - 7.4e-27 94.0 0.0 1.1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EMR70306.1 - 0.00014 21.6 0.1 0.00028 20.6 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain MarR_2 PF12802.2 EMR70306.1 - 0.017 14.7 0.1 0.11 12.1 0.0 2.2 1 1 1 2 2 2 0 MarR family Rrf2 PF02082.15 EMR70306.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator DIOX_N PF14226.1 EMR70307.1 - 5.7e-23 81.6 0.0 7e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal HAD_2 PF13419.1 EMR70308.1 - 1.2e-09 38.6 0.0 7.9e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR70308.1 - 1.7e-05 24.4 0.0 3.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EMR70308.1 - 0.0021 18.4 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_M28 PF04389.12 EMR70309.1 - 3.9e-25 88.6 0.3 1.2e-24 87.0 0.2 1.7 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EMR70309.1 - 6.8e-06 25.7 0.0 9.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EMR70309.1 - 0.00083 18.2 0.0 0.0016 17.2 0.0 1.5 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase fn3 PF00041.16 EMR70309.1 - 0.0024 17.9 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Tape_meas_lam_C PF09718.5 EMR70310.1 - 0.0058 16.5 0.9 0.2 11.6 0.0 2.6 1 1 1 2 2 2 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ArfGap PF01412.13 EMR70310.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Glyco_hydro_61 PF03443.9 EMR70311.1 - 1.4e-48 165.6 0.0 1.6e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CPSase_sm_chain PF00988.17 EMR70312.1 - 4e-47 158.9 0.0 8.2e-47 157.9 0.0 1.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EMR70312.1 - 2.3e-46 157.6 0.0 3.2e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EMR70312.1 - 7.7e-07 28.7 0.3 0.00014 21.4 0.2 3.0 1 1 0 1 1 1 1 Peptidase C26 DHC_N1 PF08385.7 EMR70314.1 - 7.6e-184 612.3 22.4 7.6e-184 612.3 15.5 4.0 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EMR70314.1 - 2.2e-129 431.5 5.1 2.2e-129 431.5 3.5 4.9 4 1 0 4 4 3 2 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EMR70314.1 - 1.1e-98 331.1 0.0 9.6e-98 328.0 0.0 2.7 3 0 0 3 3 3 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EMR70314.1 - 2.4e-78 262.8 0.0 6e-78 261.5 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 EMR70314.1 - 2.8e-41 141.2 0.4 5.3e-40 137.0 0.3 2.8 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 EMR70314.1 - 3.2e-41 140.6 0.1 1.3e-40 138.6 0.1 2.2 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 EMR70314.1 - 1.2e-37 129.4 6.5 1.2e-37 129.4 4.5 2.5 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EMR70314.1 - 3e-31 107.9 0.0 1.3e-11 44.3 0.0 5.9 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EMR70314.1 - 3.2e-20 72.3 0.0 4.2e-19 68.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EMR70314.1 - 2e-14 53.8 1.6 0.017 15.2 0.0 6.4 7 0 0 7 7 5 3 AAA domain AAA PF00004.24 EMR70314.1 - 4.6e-13 49.5 0.0 0.002 18.3 0.0 4.7 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMR70314.1 - 2.3e-10 41.3 0.2 0.039 14.7 0.0 6.1 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.1 EMR70314.1 - 4.2e-10 39.6 0.2 0.34 10.7 0.0 5.7 5 0 0 5 5 5 3 AAA domain AAA_18 PF13238.1 EMR70314.1 - 1.3e-09 38.4 1.5 0.0054 17.0 0.0 5.9 6 0 0 6 6 6 2 AAA domain AAA_14 PF13173.1 EMR70314.1 - 1.7e-06 27.9 0.0 0.22 11.4 0.0 5.4 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 EMR70314.1 - 2.3e-06 27.0 0.0 0.37 10.3 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SE PF00437.15 EMR70314.1 - 7.6e-06 25.0 0.0 0.095 11.5 0.0 3.7 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_19 PF13245.1 EMR70314.1 - 1.8e-05 24.3 0.0 0.89 9.3 0.0 4.6 4 0 0 4 4 4 1 Part of AAA domain AAA_16 PF13191.1 EMR70314.1 - 1.9e-05 24.7 24.7 0.18 11.7 0.1 9.0 8 1 2 10 10 9 2 AAA ATPase domain Mg_chelatase PF01078.16 EMR70314.1 - 2.2e-05 23.7 0.7 0.5 9.4 0.0 4.5 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EMR70314.1 - 0.0001 22.6 0.1 5.3 7.3 0.0 4.8 3 0 0 3 3 3 1 ABC transporter Zeta_toxin PF06414.7 EMR70314.1 - 0.00048 19.2 2.5 0.97 8.4 0.0 4.6 4 0 0 4 4 4 2 Zeta toxin AAA_25 PF13481.1 EMR70314.1 - 0.0039 16.6 0.1 0.33 10.3 0.0 3.6 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 EMR70314.1 - 0.0099 16.0 0.1 42 4.3 0.0 4.7 4 0 0 4 4 4 0 RNA helicase MobB PF03205.9 EMR70314.1 - 0.03 14.0 0.1 13 5.5 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B End3 PF12761.2 EMR70316.1 - 0.0072 15.9 0.9 0.0088 15.7 0.6 1.1 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 DUF4618 PF15397.1 EMR70316.1 - 0.011 15.0 1.1 0.016 14.5 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Tektin PF03148.9 EMR70316.1 - 0.017 13.6 5.6 0.024 13.1 3.9 1.1 1 0 0 1 1 1 0 Tektin family Angiomotin_C PF12240.3 EMR70316.1 - 0.026 14.0 1.2 0.039 13.4 0.8 1.2 1 0 0 1 1 1 0 Angiomotin C terminal LRS4 PF10422.4 EMR70316.1 - 0.031 13.6 0.3 0.031 13.6 0.2 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF1672 PF07901.6 EMR70316.1 - 0.04 12.9 0.2 0.05 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) Streptin-Immun PF11083.3 EMR70316.1 - 0.041 13.8 1.6 0.063 13.2 1.1 1.3 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein PEP-utilisers_N PF05524.8 EMR70316.1 - 0.045 13.5 0.2 0.067 12.9 0.2 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF4200 PF13863.1 EMR70316.1 - 0.047 13.6 10.1 0.072 13.0 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF262 PF03235.9 EMR70316.1 - 0.048 13.6 1.0 0.055 13.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF641 PF04859.7 EMR70316.1 - 0.053 13.2 2.3 0.11 12.2 1.1 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) ATG16 PF08614.6 EMR70316.1 - 0.057 13.2 4.3 0.079 12.7 3.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Prefoldin_2 PF01920.15 EMR70316.1 - 0.065 13.0 5.0 0.12 12.1 3.4 1.4 1 0 0 1 1 1 0 Prefoldin subunit DUF3391 PF11871.3 EMR70316.1 - 0.089 13.0 1.1 0.12 12.5 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Med9 PF07544.8 EMR70316.1 - 0.093 12.4 6.5 0.3 10.8 4.3 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 EMR70316.1 - 0.13 11.8 0.6 0.16 11.5 0.4 1.2 1 0 0 1 1 1 0 IncA protein NTS PF15447.1 EMR70316.1 - 0.18 12.2 1.6 0.32 11.3 1.1 1.4 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 COG2 PF06148.6 EMR70316.1 - 0.26 11.1 2.4 0.62 9.9 1.6 1.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Radical_SAM PF04055.16 EMR70317.1 - 3.5e-23 82.6 0.1 1.1e-22 80.9 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Wyosine_form PF08608.7 EMR70317.1 - 1.1e-21 76.7 0.0 2.7e-21 75.4 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EMR70317.1 - 8.6e-08 32.2 0.4 2.5e-06 27.5 0.3 2.4 1 1 0 1 1 1 1 Flavodoxin MAS20 PF02064.10 EMR70319.1 - 5.8e-16 58.4 0.8 2.8e-15 56.3 0.6 1.8 1 1 0 1 1 1 1 MAS20 protein import receptor Phage_min_cap2 PF06152.6 EMR70319.1 - 0.03 13.3 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 Nbs1_C PF08599.5 EMR70319.1 - 0.056 13.3 0.1 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 DUF1542 PF07564.6 EMR70319.1 - 0.48 10.4 1.9 1.1 9.3 1.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Metallophos PF00149.23 EMR70320.1 - 5.7e-44 149.9 1.0 7.3e-44 149.5 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3112 PF11309.3 EMR70321.1 - 1.5e-15 57.3 9.2 8.1e-14 51.7 0.1 3.5 3 2 0 3 3 3 2 Protein of unknown function (DUF3112) SUR7 PF06687.7 EMR70321.1 - 0.17 11.4 4.4 2.8 7.4 3.0 2.3 1 1 0 1 1 1 0 SUR7/PalI family zf-C2H2_4 PF13894.1 EMR70322.1 - 0.032 14.5 4.0 0.092 13.1 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger COPI_assoc PF08507.5 EMR70323.1 - 2.1e-44 150.5 4.3 2.3e-44 150.4 3.0 1.0 1 0 0 1 1 1 1 COPI associated protein UCR_Fe-S_N PF10399.4 EMR70323.1 - 0.022 13.8 1.1 0.046 12.8 0.7 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Neurensin PF14927.1 EMR70323.1 - 1 8.7 7.6 3.9 6.8 5.2 2.3 1 1 0 1 1 1 0 Neurensin SAP PF02037.22 EMR70324.1 - 6.8e-14 50.9 0.3 1.3e-13 50.0 0.2 1.5 1 0 0 1 1 1 1 SAP domain ETF PF01012.16 EMR70325.1 - 3.1e-37 127.8 2.7 3.9e-37 127.5 1.9 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Acetyltransf_1 PF00583.19 EMR70326.1 - 0.00011 22.1 0.1 0.00019 21.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR70326.1 - 0.00068 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4064 PF13273.1 EMR70326.1 - 0.018 15.1 0.1 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Abi PF02517.11 EMR70326.1 - 0.088 12.9 0.5 0.14 12.3 0.4 1.3 1 0 0 1 1 1 0 CAAX protease self-immunity Histone PF00125.19 EMR70327.1 - 1.9e-07 31.1 0.1 2.4e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Vps51 PF08700.6 EMR70328.1 - 5.7e-11 42.1 2.6 5.7e-11 42.1 1.8 2.1 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.1 EMR70328.1 - 0.0011 18.7 9.0 0.14 11.9 1.0 2.6 3 0 0 3 3 3 2 Exocyst complex component Sec5 DUF4047 PF13256.1 EMR70328.1 - 0.056 13.4 0.9 0.31 11.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Laminin_B PF00052.13 EMR70328.1 - 0.11 12.0 0.8 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 Laminin B (Domain IV) COG2 PF06148.6 EMR70328.1 - 0.2 11.5 6.6 2.1 8.2 0.5 3.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 EMR70328.1 - 1.2 8.9 5.9 2.6 7.8 0.3 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 EMR70328.1 - 3.3 5.4 8.6 0.14 9.9 1.4 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PI3_PI4_kinase PF00454.22 EMR70330.1 - 1.9e-49 168.2 0.0 4.1e-49 167.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EMR70330.1 - 3.1e-17 61.7 0.0 7.3e-17 60.5 0.0 1.7 1 0 0 1 1 1 1 FATC domain UME PF08064.8 EMR70330.1 - 2.6e-12 46.6 2.2 4.5e-12 45.8 0.0 2.6 3 0 0 3 3 3 1 UME (NUC010) domain FAT PF02259.18 EMR70330.1 - 2.7e-06 26.6 3.3 0.00033 19.7 0.1 3.1 3 1 1 4 4 4 2 FAT domain TPR_19 PF14559.1 EMR70330.1 - 0.039 14.2 0.0 0.19 12.0 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat zf-PARP PF00645.13 EMR70331.1 - 6.9e-21 74.2 0.5 1.2e-20 73.4 0.3 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PGI PF00342.14 EMR70333.1 - 8.1e-41 139.9 0.0 8.9e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase MFS_1 PF07690.11 EMR70335.1 - 2.6e-13 49.4 10.4 2.7e-12 46.0 7.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR70335.1 - 2.5e-06 26.3 0.7 2.5e-06 26.3 0.5 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter Sensor PF13796.1 EMR70335.1 - 0.0011 18.6 4.8 0.0064 16.1 2.2 2.6 1 1 0 1 1 1 1 Putative sensor PRTase_3 PF15610.1 EMR70335.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 PRTase ComF-like NfeD PF01957.13 EMR70335.1 - 0.67 10.0 0.0 0.67 10.0 0.0 2.8 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding AA_permease_2 PF13520.1 EMR70336.1 - 4.2e-53 180.4 26.1 5.1e-53 180.1 18.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMR70336.1 - 1e-11 43.8 24.1 1.3e-11 43.5 16.7 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_C69 PF03577.10 EMR70338.1 - 6.4e-20 71.4 0.0 9.2e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C69 adh_short PF00106.20 EMR70339.1 - 6.1e-15 55.5 0.2 8.6e-15 55.0 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR70339.1 - 1.2e-14 54.7 0.3 1e-07 31.9 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR70339.1 - 6.8e-08 32.3 0.1 9.5e-08 31.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMR70339.1 - 0.078 11.8 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 EMR70340.1 - 6.5e-17 61.2 15.7 5.8e-16 58.1 9.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR70340.1 - 0.00011 20.9 6.0 0.00017 20.3 4.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter OAD_beta PF03977.8 EMR70340.1 - 0.033 12.9 0.7 0.079 11.6 0.4 1.6 1 1 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit DUF1774 PF08611.5 EMR70342.1 - 1.4e-33 114.8 5.4 1.4e-33 114.8 3.8 2.4 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) PS-DH PF14765.1 EMR70343.1 - 3.2e-67 226.8 0.0 5e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 EMR70343.1 - 4.3e-67 226.2 0.0 1.2e-66 224.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMR70343.1 - 5.5e-61 206.6 0.0 1e-60 205.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EMR70343.1 - 9.8e-59 198.0 0.9 2.9e-58 196.5 0.6 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR70343.1 - 3.4e-49 166.9 4.1 4.5e-49 166.5 0.9 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMR70343.1 - 1.4e-22 79.7 1.8 1.3e-21 76.6 0.2 2.8 1 1 1 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EMR70343.1 - 5.5e-06 25.9 0.2 2.5e-05 23.8 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR70343.1 - 3.4e-05 23.5 0.2 9.4e-05 22.1 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EMR70343.1 - 4.7e-05 23.5 0.1 0.0015 18.7 0.0 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Pyr_redox_3 PF13738.1 EMR70344.1 - 7.9e-26 91.3 0.0 2.5e-23 83.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR70344.1 - 4.2e-10 38.4 0.0 2.5e-06 25.9 0.0 2.6 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EMR70344.1 - 4.4e-10 38.9 0.1 2.6e-07 29.8 0.0 3.3 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMR70344.1 - 1.5e-05 24.9 0.0 0.0003 20.7 0.0 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR70344.1 - 1.8e-05 24.5 0.1 0.23 11.1 0.0 3.0 2 1 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EMR70344.1 - 0.016 14.1 0.0 0.15 10.9 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 EMR70344.1 - 0.017 14.2 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EMR70344.1 - 0.031 12.7 0.0 1.2 7.5 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_8 PF13450.1 EMR70344.1 - 0.063 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ribonuclease_T2 PF00445.13 EMR70346.1 - 1.3e-28 99.9 0.4 2.1e-28 99.2 0.3 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Sec62 PF03839.11 EMR70347.1 - 2.9e-54 183.8 0.2 2.9e-54 183.8 0.1 1.9 2 0 0 2 2 2 1 Translocation protein Sec62 YopE_N PF09020.5 EMR70347.1 - 0.26 11.3 2.6 0.6 10.1 1.8 1.6 1 0 0 1 1 1 0 YopE, N terminal APC_CDC26 PF10471.4 EMR70347.1 - 4 8.2 11.7 0.46 11.2 1.5 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Corona_M PF01635.13 EMR70347.1 - 6.6 5.6 7.6 13 4.6 5.3 1.4 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein DUF3632 PF12311.3 EMR70348.1 - 4.9e-07 29.7 0.1 7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Beta-lactamase PF00144.19 EMR70349.1 - 8e-55 186.1 0.2 1.1e-54 185.7 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.1 EMR70349.1 - 0.098 12.0 0.0 0.53 9.7 0.0 2.1 2 1 0 2 2 2 0 Beta-lactamase enzyme family Chorismate_synt PF01264.16 EMR70350.1 - 3.3e-127 423.7 0.0 3.9e-127 423.4 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Fil_haemagg PF05594.9 EMR70351.1 - 0.57 10.5 2.8 1 9.7 1.9 1.4 1 0 0 1 1 1 0 Haemagluttinin repeat Clathrin PF00637.15 EMR70352.1 - 2.8e-23 82.0 5.6 3.5e-22 78.5 2.1 2.6 2 1 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.3 EMR70352.1 - 1e-13 50.8 0.5 6.7e-07 29.0 0.0 2.7 2 0 0 2 2 2 2 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 EMR70352.1 - 6.3e-05 22.7 0.5 0.00015 21.4 0.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMR70352.1 - 0.0021 17.7 0.3 0.0046 16.6 0.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.1 EMR70352.1 - 0.012 15.2 0.2 0.059 13.0 0.0 2.3 2 0 0 2 2 1 0 TPR repeat TPR_14 PF13428.1 EMR70352.1 - 0.016 15.8 0.6 5.2 7.9 0.4 3.6 2 1 0 2 2 2 0 Tetratricopeptide repeat zf-Apc11 PF12861.2 EMR70352.1 - 0.029 14.2 0.4 0.08 12.7 0.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EMR70352.1 - 0.059 13.4 0.8 0.16 12.1 0.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger TPR_8 PF13181.1 EMR70352.1 - 0.081 12.7 2.1 0.3 10.9 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 EMR70352.1 - 0.14 11.8 0.5 0.42 10.2 0.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMR70352.1 - 0.19 11.7 4.6 0.34 10.9 1.0 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.1 EMR70352.1 - 0.52 10.2 0.0 0.52 10.2 0.0 4.1 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF3632 PF12311.3 EMR70353.1 - 1.4e-19 70.5 0.0 2.4e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Fungal_trans PF04082.13 EMR70354.1 - 8.3e-10 37.9 2.0 3.5e-08 32.6 0.3 2.6 2 1 1 3 3 3 2 Fungal specific transcription factor domain TatD_DNase PF01026.16 EMR70355.1 - 1.3e-35 122.8 0.0 1.4e-32 112.9 0.0 2.3 2 0 0 2 2 2 2 TatD related DNase DUF2457 PF10446.4 EMR70355.1 - 0.86 8.2 7.3 0.082 11.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Hamartin PF04388.7 EMR70355.1 - 3.6 6.1 5.6 5.7 5.4 3.9 1.2 1 0 0 1 1 1 0 Hamartin protein Phostensin_N PF13916.1 EMR70356.1 - 0.13 12.2 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal CENP-N PF05238.8 EMR70357.1 - 1.8e-121 405.9 0.1 2.6e-120 402.1 0.1 1.9 1 1 0 1 1 1 1 Kinetochore protein CHL4 like Ribonuc_red_lgC PF02867.10 EMR70358.1 - 5.3e-220 731.5 0.0 8e-220 730.9 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EMR70358.1 - 6.9e-24 83.4 0.0 5.5e-23 80.5 0.0 2.3 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EMR70358.1 - 7.1e-17 61.6 0.3 1.7e-16 60.4 0.0 1.8 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 EMR70358.1 - 0.07 11.1 0.0 0.12 10.4 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Glycos_transf_1 PF00534.15 EMR70359.1 - 2.3e-30 105.2 0.0 2.9e-18 65.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EMR70359.1 - 7.9e-07 29.3 2.5 7.9e-07 29.3 1.7 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EMR70359.1 - 3.9e-05 23.8 0.0 0.017 15.3 0.0 2.8 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EMR70359.1 - 4.3e-05 23.2 0.1 0.16 11.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 EMR70359.1 - 0.1 12.8 0.0 0.63 10.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 MFS_1 PF07690.11 EMR70360.1 - 7e-44 149.9 38.1 1.2e-43 149.1 22.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR70360.1 - 6.5e-11 41.1 4.9 1e-10 40.4 3.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMR70360.1 - 1.3e-05 23.9 27.7 0.00015 20.4 19.2 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter FPN1 PF06963.7 EMR70360.1 - 0.0063 14.9 0.1 0.0063 14.9 0.1 1.8 2 0 0 2 2 2 1 Ferroportin1 (FPN1) DUF2178 PF09946.4 EMR70360.1 - 3.4 7.4 9.3 0.16 11.7 1.4 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) bZIP_2 PF07716.10 EMR70361.1 - 1.3e-11 44.1 11.4 2.2e-11 43.3 7.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EMR70361.1 - 0.00016 21.5 13.1 0.00048 20.0 9.1 1.8 1 1 0 1 1 1 1 bZIP transcription factor CALCOCO1 PF07888.6 EMR70361.1 - 0.0045 15.3 4.7 0.0055 15.0 3.3 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like XhlA PF10779.4 EMR70361.1 - 0.019 14.8 3.3 0.032 14.1 2.3 1.4 1 0 0 1 1 1 0 Haemolysin XhlA TSC22 PF01166.13 EMR70361.1 - 0.07 13.1 2.1 0.12 12.3 1.4 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family FlgN PF05130.7 EMR70361.1 - 0.13 12.4 4.9 0.18 12.0 3.4 1.1 1 0 0 1 1 1 0 FlgN protein Biotin_carb_C PF02785.14 EMR70361.1 - 0.15 12.0 0.6 0.24 11.4 0.4 1.4 1 1 0 1 1 1 0 Biotin carboxylase C-terminal domain IncA PF04156.9 EMR70361.1 - 0.2 11.2 2.5 0.25 10.9 1.8 1.1 1 0 0 1 1 1 0 IncA protein Macoilin PF09726.4 EMR70361.1 - 0.98 7.6 8.0 1.2 7.2 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Herpes_UL25 PF01499.11 EMR70361.1 - 2.9 6.0 6.7 3.2 5.9 4.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family NAD_binding_4 PF07993.7 EMR70362.1 - 2.1e-29 102.2 0.0 3.1e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EMR70362.1 - 3.7e-12 45.3 0.0 1e-10 40.6 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EMR70362.1 - 6.2e-11 42.1 0.0 4.5e-10 39.3 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMR70362.1 - 1.6e-07 31.4 0.0 4.3e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 EMR70362.1 - 0.00013 22.0 0.0 0.00065 19.7 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EMR70362.1 - 0.0012 19.0 0.0 0.0035 17.6 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EMR70362.1 - 0.012 14.3 0.0 1.6 7.3 0.0 2.2 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMR70362.1 - 0.071 11.9 0.0 0.74 8.6 0.1 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF3632 PF12311.3 EMR70363.1 - 7e-09 35.7 0.0 8.1e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Clr5 PF14420.1 EMR70364.1 - 1.3e-16 60.2 0.8 5.6e-16 58.1 0.2 2.3 2 0 0 2 2 2 1 Clr5 domain CN_hydrolase PF00795.17 EMR70364.1 - 0.0047 16.2 0.0 0.0091 15.3 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HtrL_YibB PF09612.5 EMR70365.1 - 0.023 13.9 0.0 0.91 8.7 0.0 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) BPL_LplA_LipB PF03099.14 EMR70367.1 - 6e-13 48.9 0.0 1.9e-12 47.3 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family MutL_C PF08676.6 EMR70368.1 - 2.4e-05 23.9 0.0 0.014 15.0 0.0 3.3 3 0 0 3 3 3 3 MutL C terminal dimerisation domain NmrA PF05368.8 EMR70369.1 - 1.5e-33 115.9 0.0 1.3e-31 109.7 0.0 2.0 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EMR70369.1 - 1.9e-09 37.7 0.1 6.4e-09 36.0 0.0 1.7 1 1 1 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMR70369.1 - 1.2e-06 27.4 0.0 1.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EMR70369.1 - 0.0023 17.8 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EMR70369.1 - 0.004 16.6 0.0 0.007 15.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.11 EMR70369.1 - 0.008 16.7 0.0 0.019 15.5 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase TrkA_N PF02254.13 EMR70369.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.5 2 0 0 2 2 2 0 TrkA-N domain KR PF08659.5 EMR70369.1 - 0.028 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.19 EMR70369.1 - 0.081 13.2 0.0 0.16 12.3 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DAO PF01266.19 EMR70370.1 - 1.5e-31 109.6 4.1 3e-31 108.6 2.9 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pkinase PF00069.20 EMR70371.1 - 1.1e-51 175.4 0.0 2e-35 122.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR70371.1 - 1.5e-22 79.9 0.5 3.4e-11 42.7 0.0 3.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EMR70371.1 - 9e-06 24.8 0.0 5.7e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EMR70371.1 - 0.00013 21.7 0.7 0.003 17.3 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Fungal_trans PF04082.13 EMR70372.1 - 9.1e-12 44.3 0.0 9.9e-12 44.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nitroreductase PF00881.19 EMR70373.1 - 1.7e-09 37.7 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TarH PF02203.10 EMR70374.1 - 0.027 14.3 0.2 0.035 13.9 0.1 1.1 1 0 0 1 1 1 0 Tar ligand binding domain homologue Seryl_tRNA_N PF02403.17 EMR70374.1 - 0.028 14.4 2.8 0.036 14.0 1.9 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.7 EMR70374.1 - 0.058 13.1 3.9 0.073 12.8 2.7 1.0 1 0 0 1 1 1 0 Laminin Domain II Phage_GPO PF05929.6 EMR70374.1 - 0.15 11.2 1.2 0.18 11.0 0.8 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IncA PF04156.9 EMR70374.1 - 0.26 10.8 2.3 0.32 10.5 1.6 1.1 1 0 0 1 1 1 0 IncA protein DUF3500 PF12006.3 EMR70375.1 - 1.3e-92 310.1 0.0 1.5e-92 309.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) FAD_binding_3 PF01494.14 EMR70376.1 - 3.6e-89 299.2 0.0 4.4e-89 299.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR70376.1 - 1e-05 24.6 0.6 0.028 13.3 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR70376.1 - 8.8e-05 22.4 0.0 0.0078 16.1 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR70376.1 - 0.0087 15.1 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EMR70376.1 - 0.017 15.5 0.1 0.69 10.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR70376.1 - 0.02 14.8 0.7 0.055 13.4 0.5 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMR70376.1 - 0.12 11.1 2.7 0.26 10.0 1.2 1.9 2 0 0 2 2 2 0 FAD binding domain ThiF PF00899.16 EMR70376.1 - 0.19 11.5 2.6 0.48 10.2 1.3 1.9 1 1 1 2 2 2 0 ThiF family EcoR124_C PF12008.3 EMR70377.1 - 0.09 11.9 5.4 0.12 11.5 3.7 1.1 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal PNPase PF03726.9 EMR70377.1 - 0.12 12.7 2.0 0.26 11.5 1.4 1.6 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF16 PF01519.11 EMR70377.1 - 0.25 11.5 2.9 1.4 9.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 Fib_alpha PF08702.5 EMR70377.1 - 0.46 10.5 5.1 8.5 6.4 0.4 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 EMR70377.1 - 3.4 7.9 6.8 14 5.9 1.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Melibiase PF02065.13 EMR70378.1 - 2.8e-17 62.5 0.0 1.2e-16 60.4 0.0 1.8 1 1 1 2 2 2 1 Melibiase CFEM PF05730.6 EMR70379.1 - 3.5e-11 42.7 5.2 6.4e-11 41.9 3.6 1.4 1 0 0 1 1 1 1 CFEM domain DUF3397 PF11877.3 EMR70380.1 - 0.35 10.8 0.1 0.35 10.8 0.1 3.6 3 2 0 3 3 3 0 Protein of unknown function (DUF3397) FAA_hydrolase PF01557.13 EMR70381.1 - 4.8e-64 215.7 0.0 6.6e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Sugar_tr PF00083.19 EMR70383.1 - 3.3e-103 345.7 21.4 4e-103 345.3 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR70383.1 - 8.3e-30 103.6 43.0 2.4e-27 95.6 12.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR70383.1 - 0.00023 19.5 0.5 0.00023 19.5 0.4 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EMR70383.1 - 0.24 9.4 9.7 0.026 12.6 1.5 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_1 PF07690.11 EMR70384.1 - 7e-31 107.2 31.0 7e-31 107.2 21.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily PRA1 PF03208.14 EMR70385.1 - 2.3e-38 130.9 1.4 2.8e-38 130.6 1.0 1.0 1 0 0 1 1 1 1 PRA1 family protein Ilm1 PF10311.4 EMR70386.1 - 1.1e-41 142.1 0.4 1.2e-41 141.9 0.3 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 IF-2B PF01008.12 EMR70387.1 - 8.1e-68 228.4 0.0 9.7e-68 228.1 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family TRAPPC10 PF12584.3 EMR70388.1 - 1.1e-15 57.4 0.0 9.4e-10 38.1 0.0 2.5 2 0 0 2 2 2 2 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 EMR70388.1 - 0.0007 19.1 0.8 0.0013 18.2 0.6 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 Rubis-subs-bind PF09273.6 EMR70388.1 - 0.093 12.6 0.3 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding Zn_clus PF00172.13 EMR70390.1 - 3.5e-05 23.6 7.5 5.6e-05 22.9 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.3 EMR70390.1 - 0.00038 20.1 5.5 0.00038 20.1 3.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) SSP160 PF06933.6 EMR70390.1 - 0.0033 15.5 10.1 0.0041 15.1 7.0 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.6 EMR70390.1 - 0.0033 15.3 1.8 0.0054 14.6 1.2 1.3 1 1 0 1 1 1 1 Sporozoite P67 surface antigen Dicty_REP PF05086.7 EMR70390.1 - 0.6 7.7 5.8 0.99 7.0 4.0 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4551 PF15087.1 EMR70390.1 - 1 7.6 4.3 1.4 7.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hid1 PF12722.2 EMR70390.1 - 1.1 6.8 3.1 1.1 6.8 2.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_capsid PF06112.6 EMR70390.1 - 1.3 9.0 5.9 1.2 9.2 3.3 1.5 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein SOG2 PF10428.4 EMR70390.1 - 1.9 7.0 8.9 2.4 6.7 6.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FAM176 PF14851.1 EMR70390.1 - 1.9 8.1 8.6 4.6 6.9 5.9 1.7 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.5 EMR70390.1 - 3.8 7.7 7.2 1.2 9.4 0.4 2.6 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF2413 PF10310.4 EMR70390.1 - 4.2 6.0 13.8 0.11 11.3 5.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) Pap_E4 PF02711.9 EMR70390.1 - 5.2 7.9 19.1 3.9 8.3 1.5 2.5 2 0 0 2 2 2 0 E4 protein M20_dimer PF07687.9 EMR70391.1 - 2.8e-18 65.7 0.1 5.7e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EMR70391.1 - 8e-17 61.3 0.2 1.3e-16 60.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 EMR70391.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 PITH PF06201.8 EMR70392.1 - 1.5e-42 144.9 0.1 2e-42 144.5 0.1 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EMR70392.1 - 1.2e-23 82.7 0.0 2.1e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EMR70392.1 - 3.6e-06 26.9 0.0 0.00055 19.9 0.0 2.5 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EMR70392.1 - 1e-05 25.7 0.0 4e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EMR70392.1 - 0.0034 16.9 0.3 0.091 12.3 0.0 2.7 2 1 1 3 3 3 1 Redoxin Thioredoxin_9 PF14595.1 EMR70392.1 - 0.024 14.2 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.1 EMR70392.1 - 0.07 13.1 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Tannase PF07519.6 EMR70393.1 - 3e-74 250.4 7.8 1.2e-71 241.9 5.4 3.2 1 1 0 1 1 1 1 Tannase and feruloyl esterase PAN_4 PF14295.1 EMR70394.1 - 3.7e-06 26.5 1.5 5.6e-06 25.9 1.0 1.4 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 EMR70394.1 - 0.00027 20.4 0.9 0.00039 19.9 0.6 1.3 1 0 0 1 1 1 1 PAN-like domain PAN_1 PF00024.21 EMR70394.1 - 0.00081 19.0 0.9 0.0011 18.6 0.6 1.3 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 EMR70394.1 - 0.092 12.5 5.1 0.045 13.6 2.1 1.5 2 0 0 2 2 2 0 PAN-like domain WAP PF00095.16 EMR70394.1 - 0.1 12.5 2.0 0.1 12.5 1.4 2.1 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' DnaJ PF00226.26 EMR70395.1 - 1.3e-19 69.6 0.5 2.1e-19 69.0 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 EMR70395.1 - 0.0018 18.3 1.1 0.0028 17.7 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.4 EMR70395.1 - 0.019 15.0 3.7 0.035 14.2 2.5 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF4414 PF14377.1 EMR70395.1 - 0.037 13.9 2.6 0.078 12.8 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) SRR PF07709.6 EMR70395.1 - 0.17 12.1 0.4 23 5.7 0.0 2.9 2 0 0 2 2 2 0 Seven Residue Repeat dsDNA_bind PF01984.15 EMR70395.1 - 7.7 6.5 11.4 16 5.5 7.9 1.5 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Patatin PF01734.17 EMR70396.1 - 0.0091 15.9 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase Prenyltrans PF00432.16 EMR70398.1 - 4.6e-40 134.8 3.9 3.5e-09 36.0 0.0 6.4 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EMR70398.1 - 2.2e-20 73.1 0.0 1.1e-12 48.3 0.0 4.3 2 1 3 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EMR70398.1 - 8.9e-07 28.9 0.1 0.0024 17.8 0.0 3.9 2 1 1 3 3 3 2 Prenyltransferase-like Hydantoinase_A PF01968.13 EMR70399.1 - 8.7e-80 267.9 4.3 3.9e-79 265.7 0.3 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.9 EMR70399.1 - 2.2e-60 204.4 0.0 5.3e-58 196.5 0.0 2.2 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.8 EMR70399.1 - 3e-48 163.6 1.8 1.1e-45 155.2 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EMR70399.1 - 4.2e-05 22.0 3.3 0.044 12.1 0.1 2.5 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 EMR70399.1 - 0.12 11.6 1.1 0.86 8.8 0.1 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DIOX_N PF14226.1 EMR70400.1 - 2.5e-28 98.9 0.1 3.7e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMR70400.1 - 3e-21 75.5 0.0 6.8e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DnaI_N PF07319.6 EMR70400.1 - 0.035 14.3 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus MFS_1 PF07690.11 EMR70401.1 - 2.6e-34 118.5 27.2 2.6e-34 118.5 18.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EMR70401.1 - 0.00094 19.1 0.1 0.00094 19.1 0.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) HAMP PF00672.20 EMR70401.1 - 0.71 10.0 0.1 0.71 10.0 0.0 2.6 3 0 0 3 3 3 0 HAMP domain HpcH_HpaI PF03328.9 EMR70402.1 - 1.8e-31 108.7 0.0 2.4e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.13 EMR70402.1 - 0.0013 17.7 1.8 0.0096 14.8 0.4 2.7 3 1 0 3 3 3 1 PEP-utilising enzyme, TIM barrel domain 2-Hacid_dh_C PF02826.14 EMR70403.1 - 6.3e-45 152.4 0.0 7.7e-45 152.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EMR70403.1 - 0.001 18.9 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 EMR70403.1 - 0.0036 17.1 0.0 0.0052 16.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EMR70403.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Amidase PF01425.16 EMR70404.1 - 1.7e-16 60.1 0.0 6.6e-16 58.2 0.0 1.8 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.11 EMR70405.1 - 2.8e-31 108.5 25.7 4.8e-31 107.7 17.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3311 PF11755.3 EMR70405.1 - 0.094 12.2 4.0 1.5 8.4 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) Peptidase_M14 PF00246.19 EMR70406.1 - 6.9e-74 248.9 0.0 8.2e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Abhydrolase_6 PF12697.2 EMR70407.1 - 2.1e-10 40.9 0.6 2.9e-10 40.4 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR70407.1 - 2.2e-09 37.2 0.0 5.2e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EMR70407.1 - 9.4e-06 25.0 0.2 0.019 14.1 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Hydrolase_4 PF12146.3 EMR70407.1 - 0.0016 18.2 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase AAA PF00004.24 EMR70408.1 - 6.2e-91 301.4 0.0 8.9e-47 158.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMR70408.1 - 1.1e-13 50.7 0.0 4e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EMR70408.1 - 3.3e-13 50.5 0.2 1.4e-06 29.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EMR70408.1 - 2.5e-12 47.0 0.3 0.00035 20.7 0.1 4.5 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EMR70408.1 - 1.3e-11 44.5 0.0 1.6e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EMR70408.1 - 3.5e-11 43.4 0.8 0.00062 19.8 0.1 3.9 2 2 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 EMR70408.1 - 3.9e-11 42.9 0.0 4.6e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EMR70408.1 - 2.2e-10 40.3 0.2 0.00033 20.3 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMR70408.1 - 2.6e-10 40.4 0.0 0.00056 19.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EMR70408.1 - 4e-09 36.1 0.1 0.00069 19.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EMR70408.1 - 8.5e-09 35.0 0.4 0.0023 17.6 0.0 3.3 3 0 0 3 3 2 2 Part of AAA domain Zeta_toxin PF06414.7 EMR70408.1 - 1.3e-08 34.1 0.0 0.0011 18.1 0.0 2.9 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.1 EMR70408.1 - 2.3e-08 34.1 0.0 0.0008 19.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EMR70408.1 - 2.5e-08 34.0 0.1 0.0031 17.6 0.0 3.1 3 1 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.16 EMR70408.1 - 5.1e-08 32.3 0.3 0.0051 16.0 0.2 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EMR70408.1 - 8.7e-08 31.9 0.3 0.0052 16.4 0.0 3.7 3 1 1 4 4 4 2 NACHT domain AAA_18 PF13238.1 EMR70408.1 - 1e-07 32.2 0.0 0.0022 18.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain TIP49 PF06068.8 EMR70408.1 - 1.4e-07 30.6 0.7 0.0053 15.5 0.1 3.3 3 1 1 4 4 4 2 TIP49 C-terminus Cytidylate_kin2 PF13189.1 EMR70408.1 - 2e-07 31.0 0.0 0.00021 21.2 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_25 PF13481.1 EMR70408.1 - 2.4e-07 30.3 12.7 0.066 12.6 0.1 5.7 4 2 0 6 6 6 3 AAA domain ABC_tran PF00005.22 EMR70408.1 - 1.8e-06 28.2 0.0 0.11 12.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter Sigma54_activ_2 PF14532.1 EMR70408.1 - 9.5e-06 25.7 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain UPF0079 PF02367.12 EMR70408.1 - 1.1e-05 24.9 0.1 0.02 14.5 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 EMR70408.1 - 1.3e-05 24.8 0.0 0.039 13.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EMR70408.1 - 1.3e-05 24.2 0.1 0.043 12.7 0.0 3.4 2 2 2 4 4 3 1 Protein of unknown function (DUF815) KaiC PF06745.8 EMR70408.1 - 2.1e-05 23.7 0.3 0.54 9.3 0.0 3.2 2 1 1 3 3 3 2 KaiC Arch_ATPase PF01637.13 EMR70408.1 - 3.8e-05 23.5 0.0 1.1 8.9 0.0 3.7 2 2 1 3 3 3 2 Archaeal ATPase Rad17 PF03215.10 EMR70408.1 - 4.9e-05 22.1 0.0 0.022 13.4 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Sigma54_activat PF00158.21 EMR70408.1 - 8.7e-05 22.0 0.0 0.15 11.5 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain ATP-synt_ab PF00006.20 EMR70408.1 - 0.00012 21.6 0.0 0.34 10.3 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.13 EMR70408.1 - 0.00013 21.5 0.0 0.18 11.3 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EMR70408.1 - 0.00015 21.0 0.2 0.41 9.8 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein SKI PF01202.17 EMR70408.1 - 0.00026 20.9 0.6 0.6 9.9 0.0 2.8 3 0 0 3 3 2 2 Shikimate kinase NB-ARC PF00931.17 EMR70408.1 - 0.00029 19.8 0.0 0.29 9.9 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain Parvo_NS1 PF01057.12 EMR70408.1 - 0.001 18.0 0.1 1.3 7.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NTPase_1 PF03266.10 EMR70408.1 - 0.0019 17.9 0.2 1.1 8.9 0.0 3.1 2 1 0 3 3 3 1 NTPase AAA_11 PF13086.1 EMR70408.1 - 0.0021 17.6 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EMR70408.1 - 0.003 17.1 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Guanylate_kin PF00625.16 EMR70408.1 - 0.0044 16.4 0.9 13 5.1 0.0 4.5 3 2 2 5 5 5 0 Guanylate kinase ResIII PF04851.10 EMR70408.1 - 0.0045 16.8 0.0 2.6 7.8 0.0 2.8 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit SRPRB PF09439.5 EMR70408.1 - 0.0083 15.3 0.1 3.2 6.9 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AFG1_ATPase PF03969.11 EMR70408.1 - 0.014 14.1 0.0 2.7 6.7 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase DUF2075 PF09848.4 EMR70408.1 - 0.015 14.3 0.0 2.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.13 EMR70408.1 - 0.015 14.9 0.0 3 7.4 0.0 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein KTI12 PF08433.5 EMR70408.1 - 0.019 14.1 0.3 4.9 6.2 0.0 3.2 2 1 1 3 3 3 0 Chromatin associated protein KTI12 PduV-EutP PF10662.4 EMR70408.1 - 0.028 13.8 0.0 8.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DAP3 PF10236.4 EMR70408.1 - 0.046 12.6 0.0 10 4.9 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 CPT PF07931.7 EMR70408.1 - 0.087 12.4 0.7 2.7 7.6 0.0 2.8 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein MMR_HSR1 PF01926.18 EMR70408.1 - 0.1 12.5 0.0 9.4 6.2 0.0 3.0 2 1 1 3 3 3 0 50S ribosome-binding GTPase T2SE PF00437.15 EMR70408.1 - 0.11 11.4 0.0 5 5.9 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 EMR70408.1 - 0.11 12.0 0.2 18 4.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMR70408.1 - 0.12 11.7 3.1 7.9 5.8 0.0 3.6 5 0 0 5 5 3 0 AAA-like domain cobW PF02492.14 EMR70408.1 - 0.13 11.6 0.1 15 4.9 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.18 EMR70408.1 - 0.15 10.8 0.0 0.69 8.6 0.0 2.0 2 0 0 2 2 2 0 MCM2/3/5 family DUF258 PF03193.11 EMR70408.1 - 0.2 10.8 0.0 6.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EMR70408.1 - 1 9.6 2.5 8.7 6.6 0.0 2.8 4 0 0 4 4 2 0 AAA domain Cytochrom_C PF00034.16 EMR70409.1 - 2e-09 38.1 0.0 2.8e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EMR70409.1 - 1.6e-08 34.5 0.7 7.1e-08 32.4 0.5 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EMR70409.1 - 0.0013 18.2 0.2 0.022 14.1 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 EMR70409.1 - 0.13 11.9 0.1 0.14 11.7 0.0 1.3 1 1 0 1 1 1 0 Cytochrome C1 family PA PF02225.17 EMR70410.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 PA domain Myb_DNA-binding PF00249.26 EMR70411.1 - 0.069 13.2 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain RAM PF15320.1 EMR70411.1 - 8.6 6.7 13.5 1.6 9.0 2.9 3.4 3 0 0 3 3 3 0 mRNA cap methylation, RNMT-activating mini protein HAD_2 PF13419.1 EMR70413.1 - 3.8e-25 89.1 0.0 5.5e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Peptidase_A4 PF01828.12 EMR70414.1 - 3.9e-90 300.4 12.8 4.8e-90 300.1 8.9 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF917 PF06032.7 EMR70415.1 - 6.7e-106 353.8 0.3 1.2e-105 352.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EMR70415.1 - 1.2e-53 182.1 8.0 1.4e-52 178.6 1.0 3.7 3 1 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EMR70415.1 - 9.1e-34 116.4 0.4 4.8e-31 107.6 0.0 2.8 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 EMR70415.1 - 5.9e-07 29.0 6.7 0.00039 19.8 0.1 3.7 4 0 0 4 4 4 2 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.1 EMR70415.1 - 0.003 15.9 1.9 0.016 13.5 0.0 2.6 3 0 0 3 3 3 1 MutL protein StbA PF06406.6 EMR70415.1 - 0.0079 15.1 0.0 0.77 8.6 0.0 2.5 2 1 0 2 2 2 1 StbA protein CM_1 PF07736.6 EMR70415.1 - 0.09 12.8 0.0 0.64 10.1 0.0 2.3 2 0 0 2 2 2 0 Chorismate mutase type I p450 PF00067.17 EMR70416.1 - 2e-25 89.2 0.0 2.6e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EMR70417.1 - 3.2e-20 72.0 0.4 7.8e-20 70.7 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EMR70417.1 - 0.00066 19.5 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Epimerase PF01370.16 EMR70418.1 - 1e-06 28.3 0.0 0.00018 21.0 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EMR70418.1 - 1.2e-06 27.7 0.1 1.9e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EMR70418.1 - 1.2e-05 25.4 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EMR70418.1 - 2.4e-05 23.1 0.0 6.6e-05 21.7 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EMR70418.1 - 0.00016 20.6 0.1 0.024 13.5 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EMR70418.1 - 0.00039 19.7 0.0 0.00063 19.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EMR70418.1 - 0.0004 20.6 0.0 0.001 19.3 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EMR70418.1 - 0.11 12.5 0.2 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain DUF2500 PF10694.4 EMR70419.1 - 0.07 13.1 0.0 0.07 13.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) DUF3733 PF12534.3 EMR70419.1 - 8.1 5.8 7.6 0.35 10.1 0.1 2.5 3 0 0 3 3 3 0 Leucine-rich repeat containing protein 8 Pro-kuma_activ PF09286.6 EMR70420.1 - 7.8e-45 152.4 0.2 1.8e-43 148.0 0.1 2.3 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EMR70420.1 - 1.6e-10 40.6 0.3 3e-10 39.7 0.2 1.5 1 0 0 1 1 1 1 Subtilase family Transp_cyt_pur PF02133.10 EMR70421.1 - 1.5e-80 270.9 39.1 2.4e-80 270.2 27.1 1.3 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Man-6-P_recep PF02157.10 EMR70422.1 - 1.8e-13 50.1 0.0 3.3e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 EMR70422.1 - 1e-07 31.8 0.3 0.0015 18.3 0.2 2.4 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 EMR70422.1 - 4.4e-07 29.4 5.9 8.5e-06 25.1 4.1 2.5 1 1 0 1 1 1 1 Autophagy-related protein 27 DUF2722 PF10846.3 EMR70422.1 - 0.066 12.2 1.5 0.11 11.4 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nop14 PF04147.7 EMR70422.1 - 0.32 8.8 12.2 0.62 7.9 6.6 2.0 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 EMR70422.1 - 1 7.3 8.9 1.3 6.9 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EMR70422.1 - 1.1 8.4 8.8 1.6 7.9 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 EMR70422.1 - 3.6 6.5 7.1 5.9 5.7 4.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit p450 PF00067.17 EMR70423.1 - 1.8e-44 152.0 0.0 2.2e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMR70424.1 - 5.4e-31 107.6 0.0 7.3e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMR70425.1 - 2.8e-42 144.8 0.0 8.6e-42 143.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 NOSIC PF08060.8 EMR70425.1 - 0.023 14.4 0.1 0.074 12.8 0.0 1.8 2 0 0 2 2 2 0 NOSIC (NUC001) domain adh_short PF00106.20 EMR70426.1 - 3.4e-14 53.1 0.0 3.9e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR70426.1 - 3.5e-09 36.5 0.0 3.9e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR70426.1 - 2.1e-05 24.4 0.0 2.3e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR70426.1 - 4.3e-05 23.0 0.0 4.8e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMR70426.1 - 0.0003 19.7 0.1 0.00037 19.5 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Trp_syntA PF00290.15 EMR70426.1 - 0.089 11.3 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Eno-Rase_NADH_b PF12242.3 EMR70426.1 - 0.34 10.7 3.2 0.71 9.7 1.5 2.0 2 1 1 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.16 EMR70426.1 - 0.46 10.2 1.8 0.55 10.0 0.6 1.5 2 0 0 2 2 2 0 ThiF family adh_short PF00106.20 EMR70427.1 - 5.6e-18 65.4 1.2 8e-18 64.9 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR70427.1 - 2.3e-11 43.7 0.6 3.3e-11 43.1 0.4 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR70427.1 - 5.6e-05 23.0 0.1 0.00012 21.9 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 EMR70427.1 - 0.019 13.8 0.6 0.16 10.8 0.4 2.1 1 1 0 1 1 1 0 Male sterility protein NAD_binding_8 PF13450.1 EMR70428.1 - 4.8e-13 48.9 0.2 1.5e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMR70428.1 - 2.7e-11 43.2 0.0 2.4e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EMR70428.1 - 1e-07 31.2 0.3 6e-05 22.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EMR70428.1 - 1.4e-05 24.3 0.1 2.3e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EMR70428.1 - 0.00036 19.7 0.3 0.0021 17.1 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR70428.1 - 0.00038 19.0 0.1 0.00055 18.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EMR70428.1 - 0.00045 19.1 0.1 0.00078 18.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EMR70428.1 - 0.00055 18.9 0.0 0.017 14.0 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EMR70428.1 - 0.00073 19.3 1.4 0.014 15.2 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EMR70428.1 - 0.0013 18.8 0.0 0.044 13.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR70428.1 - 0.0019 18.1 0.2 0.0055 16.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EMR70428.1 - 0.01 15.2 0.0 0.03 13.7 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GMC_oxred_N PF00732.14 EMR70428.1 - 0.025 13.7 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase Pyr_redox PF00070.22 EMR70428.1 - 0.067 13.6 0.0 1.3 9.4 0.0 2.6 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMR70428.1 - 0.079 11.5 0.2 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ERG4_ERG24 PF01222.12 EMR70429.1 - 2.2e-169 563.5 3.1 2.5e-169 563.3 2.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EMR70429.1 - 0.00025 20.4 0.1 0.00068 19.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Rho_RNA_bind PF07497.7 EMR70429.1 - 0.14 11.8 0.0 15 5.3 0.0 2.5 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain Glyco_hydro_16 PF00722.16 EMR70430.1 - 2.5e-20 72.5 1.0 5.5e-20 71.4 0.3 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 TaqI_C PF12950.2 EMR70430.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Glyco_hydro_16 PF00722.16 EMR70431.1 - 2.1e-40 138.0 0.4 2.8e-40 137.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 EMR70432.1 - 4.9e-46 156.8 10.1 1.5e-45 155.2 6.7 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMR70432.1 - 2e-07 31.0 0.0 5.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EMR70432.1 - 6e-06 26.0 0.0 3.3e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EMR70432.1 - 0.002 17.4 0.1 0.0063 15.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Ribosomal_L3 PF00297.17 EMR70433.1 - 7.3e-117 389.4 8.5 8.8e-117 389.1 5.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Transferase PF02458.10 EMR70434.1 - 4.3e-09 35.3 0.0 5.6e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Transferase family FAD_binding_4 PF01565.18 EMR70435.1 - 1.9e-22 79.2 0.6 3.7e-22 78.2 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR70435.1 - 5.2e-05 23.0 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like LIP PF03583.9 EMR70437.1 - 1.9e-62 211.1 0.1 2.4e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Ribosomal_L34e PF01199.13 EMR70440.1 - 1.7e-37 127.4 2.5 2.2e-37 127.1 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.3 EMR70440.1 - 0.31 10.6 5.4 2.4 7.8 0.2 3.0 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain zf-ribbon_3 PF13248.1 EMR70440.1 - 0.39 9.9 2.4 0.53 9.5 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain PROCN PF08083.6 EMR70441.1 - 5e-222 736.6 6.7 7.9e-222 736.0 4.7 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EMR70441.1 - 1e-124 414.3 1.2 2e-124 413.4 0.8 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EMR70441.1 - 2.3e-98 326.1 1.3 9e-62 207.1 0.1 2.6 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EMR70441.1 - 2.7e-76 254.3 4.0 3.5e-76 254.0 1.8 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EMR70441.1 - 4.1e-67 223.9 0.1 9.1e-67 222.8 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Hom_end_hint PF05203.11 EMR70441.1 - 3.3e-50 170.7 9.3 5.9e-30 104.6 0.1 3.3 2 1 1 3 3 3 2 Hom_end-associated Hint RRM_4 PF10598.4 EMR70441.1 - 3.6e-44 148.5 0.2 9.9e-44 147.1 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EMR70441.1 - 1.6e-41 140.9 0.0 4.2e-41 139.5 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain DUF3753 PF12575.3 EMR70441.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Inhibitor_I78 PF11720.3 EMR70444.1 - 2.3e-15 56.0 0.0 3.2e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EMR70444.1 - 0.00022 21.2 0.2 0.00038 20.5 0.1 1.5 2 0 0 2 2 2 1 Potato inhibitor I family PUA PF01472.15 EMR70445.1 - 4.4e-13 48.7 0.0 2.2e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 PUA domain DUF4112 PF13430.1 EMR70446.1 - 3.8e-30 103.9 0.4 5e-30 103.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Gly_rich PF12810.2 EMR70446.1 - 0.034 13.7 0.1 0.047 13.2 0.1 1.1 1 0 0 1 1 1 0 Glycine rich protein WD40 PF00400.27 EMR70447.1 - 4.2e-14 51.8 2.0 7.8e-09 35.0 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Biotin_lipoyl PF00364.17 EMR70449.1 - 2.6e-19 68.6 0.6 4.6e-19 67.8 0.4 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EMR70449.1 - 1e-07 31.4 0.0 4.3e-07 29.4 0.0 2.1 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EMR70449.1 - 6.7e-06 25.6 0.1 7.7e-05 22.2 0.0 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like CTP_transf_2 PF01467.21 EMR70450.1 - 6.7e-06 26.2 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase Nol1_Nop2_Fmu PF01189.12 EMR70450.1 - 0.081 12.2 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 NOL1/NOP2/sun family CoA_transf_3 PF02515.12 EMR70451.1 - 1.1e-24 86.7 1.3 7.3e-23 80.8 0.7 2.7 2 1 0 2 2 2 1 CoA-transferase family III Ribonuc_red_sm PF00268.16 EMR70452.1 - 5.7e-120 399.5 1.1 6.9e-120 399.2 0.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.7 EMR70453.1 - 2.1e-28 97.8 1.1 3.3e-28 97.2 0.7 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) G-gamma PF00631.17 EMR70454.1 - 1.4e-26 91.9 0.0 1.8e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 GGL domain DUF2533 PF10752.4 EMR70456.1 - 0.14 12.4 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) Fungal_trans PF04082.13 EMR70457.1 - 7.4e-27 93.8 0.4 1.4e-26 92.9 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-HC5HC2H_2 PF13832.1 EMR70458.1 - 3.7e-34 117.0 5.9 3.7e-34 117.0 4.1 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EMR70458.1 - 1.8e-26 92.0 5.3 1.8e-26 92.0 3.7 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EMR70458.1 - 2.6e-19 70.0 0.1 1.4e-18 67.6 0.0 2.4 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 EMR70458.1 - 2.9e-14 52.0 2.1 2.9e-14 52.0 1.4 2.0 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EMR70458.1 - 7.9e-09 35.0 24.1 8.9e-08 31.7 6.7 2.7 2 0 0 2 2 2 2 PHD-finger Virulence_fact PF13769.1 EMR70458.1 - 0.023 14.5 0.3 0.1 12.4 0.2 2.1 1 0 0 1 1 1 0 Virulence factor zf-RING-like PF08746.6 EMR70458.1 - 2.4 8.2 22.2 0.04 13.9 3.9 2.7 2 0 0 2 2 2 0 RING-like domain SGL PF08450.7 EMR70461.1 - 3.3e-62 210.0 0.0 4.5e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region PD40 PF07676.7 EMR70461.1 - 0.00087 18.9 0.1 0.0034 16.9 0.0 2.0 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Arylesterase PF01731.15 EMR70461.1 - 0.047 13.6 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Arylesterase Reg_prop PF07494.6 EMR70461.1 - 0.092 12.8 0.2 5.1 7.4 0.0 3.5 3 0 0 3 3 3 0 Two component regulator propeller Glyco_hydro_16 PF00722.16 EMR70463.1 - 1.2e-09 37.7 0.1 1.7e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1810 PF08837.6 EMR70464.1 - 4.9e-45 152.5 0.1 6.4e-45 152.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1810) TINF2_N PF14973.1 EMR70464.1 - 0.1 12.7 0.1 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus TPR_17 PF13431.1 EMR70465.1 - 2.8e-08 33.3 0.8 0.01 15.9 0.1 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EMR70465.1 - 3.2e-08 33.3 2.1 0.36 10.7 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMR70465.1 - 2.5e-06 26.9 17.4 0.023 14.5 0.8 7.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMR70465.1 - 3.2e-06 27.2 21.1 0.014 16.0 0.5 8.8 10 1 1 11 11 11 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMR70465.1 - 6.3e-06 25.6 0.0 0.00041 19.9 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR70465.1 - 5.9e-05 23.3 6.4 0.022 15.1 0.2 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMR70465.1 - 0.00043 19.8 10.2 0.84 9.3 0.1 6.0 6 2 0 6 6 6 2 TPR repeat TPR_1 PF00515.23 EMR70465.1 - 0.0032 17.0 8.1 0.082 12.5 0.2 6.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMR70465.1 - 0.043 14.4 15.8 1.4 9.6 3.0 6.1 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMR70465.1 - 0.1 13.1 2.0 0.82 10.2 0.5 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Syntaxin PF00804.20 EMR70466.1 - 0.015 15.4 2.2 0.39 10.8 0.1 2.4 2 0 0 2 2 2 0 Syntaxin Apolipoprotein PF01442.13 EMR70466.1 - 0.11 12.0 8.8 0.22 11.0 6.1 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain IATP PF04568.7 EMR70466.1 - 1.3 9.0 6.9 11 6.1 0.6 3.3 3 1 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP DUF883 PF05957.8 EMR70466.1 - 2.3 8.6 7.6 0.57 10.6 0.6 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) WW PF00397.21 EMR70467.1 - 4.8e-05 23.1 5.3 4.8e-05 23.1 3.7 1.9 2 0 0 2 2 2 1 WW domain WRW PF10206.4 EMR70467.1 - 0.12 12.4 0.2 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Glyco_transf_90 PF05686.7 EMR70468.1 - 5e-15 55.1 7.6 1.6e-12 46.8 3.1 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 TPR_10 PF13374.1 EMR70468.1 - 0.011 15.6 0.1 0.024 14.5 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PCI PF01399.22 EMR70469.1 - 3.1e-08 33.8 0.3 7.1e-07 29.5 0.0 2.8 2 0 0 2 2 2 1 PCI domain DPBB_1 PF03330.13 EMR70471.1 - 1.1e-08 34.9 0.0 2.3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DEC-1_N PF04625.8 EMR70471.1 - 0.019 13.6 12.9 0.029 13.0 8.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Barwin PF00967.12 EMR70471.1 - 0.038 13.6 0.1 0.07 12.8 0.1 1.4 1 0 0 1 1 1 0 Barwin family Spore_YtfJ PF09579.5 EMR70471.1 - 0.51 10.2 4.3 2.5 7.9 0.1 2.9 3 0 0 3 3 3 0 Sporulation protein YtfJ (Spore_YtfJ) UNC45-central PF11701.3 EMR70472.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central DUF4064 PF13273.1 EMR70472.1 - 0.67 10.0 7.9 0.6 10.2 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) PTCB-BRCT PF12738.2 EMR70473.1 - 3e-27 94.2 0.2 1.8e-18 66.1 0.0 4.1 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 EMR70473.1 - 2.8e-22 78.6 1.0 4.3e-06 26.7 0.0 5.7 6 1 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain Skp1 PF01466.14 EMR70474.1 - 9.4e-21 73.6 0.0 9.4e-21 73.6 0.0 2.0 3 0 0 3 3 3 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EMR70474.1 - 2.3e-11 43.6 0.0 5.3e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 EMR70474.1 - 0.099 12.6 0.0 12 5.9 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain Glyco_hydro_28 PF00295.12 EMR70475.1 - 1.9e-36 125.6 3.4 2.9e-36 125.0 2.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 FAR1 PF03101.10 EMR70476.1 - 1e-06 29.1 0.0 1e-06 29.1 0.0 2.0 2 0 0 2 2 2 1 FAR1 DNA-binding domain adh_short PF00106.20 EMR70477.1 - 1.2e-10 41.5 4.9 4.2e-08 33.2 3.4 3.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR70477.1 - 1.1e-05 25.3 0.0 0.00011 22.0 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMR70477.1 - 0.0038 17.2 0.2 0.041 13.8 0.1 2.3 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EMR70477.1 - 0.14 11.7 4.1 16 5.1 0.2 3.4 3 1 0 3 3 3 0 KR domain 2OG-FeII_Oxy PF03171.15 EMR70478.1 - 8.1e-08 32.4 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PAS PF00989.19 EMR70479.1 - 0.0024 17.6 0.0 0.015 15.0 0.0 2.2 2 0 0 2 2 2 1 PAS fold DUF2890 PF11081.3 EMR70479.1 - 0.047 13.7 4.9 0.11 12.5 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 EMR70479.1 - 1 7.3 6.7 1.3 6.9 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Pyridox_ox_2 PF12900.2 EMR70480.1 - 4.2e-32 110.9 0.0 7.8e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GATase_6 PF13522.1 EMR70480.1 - 6.3e-10 39.1 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EMR70480.1 - 1.8e-07 30.1 0.0 2.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.16 EMR70480.1 - 1.2e-05 24.2 0.1 2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_7 PF13537.1 EMR70480.1 - 0.024 14.3 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain Zds_C PF08632.5 EMR70481.1 - 1.5e-31 107.5 0.8 2.7e-31 106.7 0.6 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Bac_rhamnosid PF05592.6 EMR70482.1 - 2.5e-12 45.8 0.1 5.6e-12 44.6 0.1 1.5 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EMR70482.1 - 0.0045 15.7 0.1 0.006 15.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF608 adh_short PF00106.20 EMR70483.1 - 4.1e-24 85.3 0.1 1.2e-23 83.8 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR70483.1 - 4.1e-18 66.0 0.1 6.2e-18 65.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR70483.1 - 1.3e-06 28.2 0.4 2.7e-06 27.1 0.1 1.6 2 0 0 2 2 2 1 KR domain Exo_endo_phos PF03372.18 EMR70483.1 - 0.00079 19.4 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HHH_5 PF14520.1 EMR70483.1 - 0.019 15.1 0.6 0.27 11.4 0.4 2.5 1 1 0 1 1 1 0 Helix-hairpin-helix domain zf-RING_2 PF13639.1 EMR70484.1 - 8.5e-12 44.7 2.5 1.3e-11 44.0 1.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EMR70484.1 - 8.3e-07 29.0 1.2 2.4e-06 27.5 0.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EMR70484.1 - 8.7e-06 25.4 1.4 1.5e-05 24.7 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EMR70484.1 - 1e-05 25.4 2.5 1.7e-05 24.7 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMR70484.1 - 2e-05 24.1 0.8 3.6e-05 23.3 0.6 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMR70484.1 - 0.00032 20.3 0.9 0.00053 19.5 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 EMR70484.1 - 0.0052 16.2 1.3 0.54 9.7 0.1 2.6 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-RING_5 PF14634.1 EMR70484.1 - 0.0065 16.1 1.3 0.016 14.9 0.9 1.6 1 1 1 2 2 2 1 zinc-RING finger domain zf-Di19 PF05605.7 EMR70484.1 - 0.009 16.1 0.6 3.7 7.7 0.0 2.6 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-UDP PF14569.1 EMR70484.1 - 0.031 14.0 1.9 0.87 9.3 0.2 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.1 EMR70484.1 - 0.04 13.8 4.1 0.083 12.7 2.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-FCS PF06467.9 EMR70484.1 - 0.047 13.3 0.6 1.3 8.7 0.1 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Rtf2 PF04641.7 EMR70484.1 - 0.12 11.5 2.8 2.9 7.0 2.0 2.0 1 1 0 1 1 1 0 Rtf2 RING-finger FANCL_C PF11793.3 EMR70484.1 - 0.12 12.3 1.2 3.4 7.6 0.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Tmpp129 PF10272.4 EMR70484.1 - 0.13 10.9 0.2 0.23 10.1 0.1 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-RING_4 PF14570.1 EMR70484.1 - 0.14 11.7 6.2 2.6 7.7 4.4 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Ndc80_HEC PF03801.8 EMR70485.1 - 2.8e-62 208.8 0.1 6.2e-62 207.7 0.1 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family WASH_WAHD PF11945.3 EMR70485.1 - 0.0014 17.9 3.2 0.0032 16.8 2.2 1.6 1 0 0 1 1 1 1 WAHD domain of WASH complex Filament PF00038.16 EMR70485.1 - 0.01 15.2 49.4 0.56 9.6 12.0 3.5 3 1 1 4 4 4 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 EMR70485.1 - 0.012 15.3 44.2 0.26 11.0 10.6 3.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein THDPS_N_2 PF14805.1 EMR70485.1 - 0.042 13.7 0.3 0.26 11.1 0.2 2.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal V_ATPase_I PF01496.14 EMR70485.1 - 0.17 9.7 30.6 0.19 9.5 6.8 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Spiralin PF05215.8 EMR70485.1 - 0.18 10.8 4.3 0.075 12.1 0.8 1.9 2 0 0 2 2 2 0 Spiralin Spc7 PF08317.6 EMR70485.1 - 0.18 10.3 39.7 0.15 10.6 9.2 2.7 2 1 0 2 2 2 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.2 EMR70485.1 - 1.3 8.8 63.2 0.23 11.2 13.3 4.4 2 2 2 4 4 4 0 Tropomyosin like NPV_P10 PF05531.7 EMR70485.1 - 4.5 7.6 14.6 6.7 7.0 1.8 4.2 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4510 PF14971.1 EMR70485.1 - 4.8 7.3 11.4 0.42 10.7 2.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) Atg14 PF10186.4 EMR70485.1 - 5.3 5.8 39.6 0.17 10.8 5.6 3.2 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 CDV3 PF15359.1 EMR70486.1 - 0.0043 17.1 0.1 0.0043 17.1 0.1 1.8 2 0 0 2 2 2 1 Carnitine deficiency-associated protein 3 DSBA PF01323.15 EMR70486.1 - 0.14 11.7 0.0 6.6 6.2 0.0 2.0 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin PF00085.15 EMR70487.1 - 3.6e-24 84.4 0.0 4e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EMR70487.1 - 2.6e-07 30.6 0.0 9.1e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EMR70487.1 - 4.6e-06 26.7 0.3 0.00027 21.1 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EMR70487.1 - 0.00011 21.8 0.1 0.00036 20.1 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EMR70487.1 - 0.0009 18.8 0.2 0.066 12.7 0.0 2.1 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.1 EMR70487.1 - 0.024 14.2 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.1 EMR70487.1 - 0.026 14.5 0.2 0.055 13.5 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like HyaE PF07449.6 EMR70487.1 - 0.041 13.7 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 EMR70487.1 - 0.069 12.9 0.0 0.22 11.3 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin domain DIM1 PF02966.11 EMR70487.1 - 0.083 12.4 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Cyt-b5 PF00173.23 EMR70489.1 - 5.5e-24 83.7 0.2 7.9e-24 83.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF347 PF03988.7 EMR70489.1 - 0.027 14.3 0.2 0.038 13.8 0.2 1.2 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) FAD_binding_3 PF01494.14 EMR70490.1 - 5.2e-18 65.2 1.7 2.3e-08 33.4 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMR70490.1 - 8e-08 32.2 0.5 2.2e-07 30.7 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR70490.1 - 2.6e-07 29.8 1.9 1.3e-06 27.5 0.9 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR70490.1 - 4.5e-06 25.7 1.6 1.8e-05 23.8 1.5 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EMR70490.1 - 2.1e-05 23.6 0.7 0.0071 15.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 EMR70490.1 - 0.00017 20.1 0.0 0.00023 19.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 EMR70490.1 - 0.00022 20.4 0.2 0.016 14.2 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EMR70490.1 - 0.00063 19.6 0.4 0.0014 18.5 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR70490.1 - 0.00064 18.6 0.2 0.001 18.0 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EMR70490.1 - 0.0017 17.5 2.2 0.0026 16.8 1.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR70490.1 - 0.0059 16.6 0.3 0.024 14.7 0.1 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR70490.1 - 0.0059 15.7 0.3 0.009 15.1 0.2 1.3 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.11 EMR70490.1 - 0.0066 15.8 0.4 0.015 14.7 0.1 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EMR70490.1 - 0.022 13.3 0.6 0.17 10.4 0.0 2.2 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.22 EMR70490.1 - 0.024 15.0 1.7 0.088 13.2 1.2 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EMR70490.1 - 0.053 13.0 1.2 0.2 11.2 0.4 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EMR70490.1 - 0.062 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Esterase_phd PF10503.4 EMR70491.1 - 3.2e-17 62.5 0.2 5.3e-17 61.7 0.2 1.3 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EMR70491.1 - 5.2e-10 38.9 0.1 8.9e-10 38.1 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMR70491.1 - 5.4e-06 26.2 0.1 6.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR70491.1 - 0.00014 21.4 0.4 0.00045 19.8 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EMR70491.1 - 0.00021 20.8 0.4 0.00035 20.0 0.2 1.4 1 1 0 1 1 1 1 Putative esterase COesterase PF00135.23 EMR70491.1 - 0.00033 19.5 0.0 0.0005 18.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EMR70491.1 - 0.00034 20.5 0.1 0.0011 18.8 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Tannase PF07519.6 EMR70491.1 - 0.038 12.7 0.1 0.24 10.0 0.0 1.9 2 0 0 2 2 2 0 Tannase and feruloyl esterase Abhydrolase_3 PF07859.8 EMR70491.1 - 0.08 12.4 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold p450 PF00067.17 EMR70492.1 - 3.1e-47 161.1 0.0 3.4e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ESCRT-II PF05871.7 EMR70493.1 - 2.8e-45 153.6 0.0 8.4e-45 152.1 0.0 1.8 1 1 1 2 2 2 1 ESCRT-II complex subunit Serglycin PF04360.7 EMR70493.1 - 0.49 10.1 9.5 0.048 13.4 3.2 1.7 1 1 1 2 2 2 0 Serglycin Pex14_N PF04695.8 EMR70493.1 - 0.71 9.9 5.4 1.3 9.1 3.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region F-actin_cap_A PF01267.12 EMR70494.1 - 1.7e-90 302.7 0.0 2.2e-90 302.3 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Transket_pyr PF02779.19 EMR70494.1 - 7.4e-43 146.0 0.0 1.2e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EMR70494.1 - 3.6e-30 104.4 0.0 7.6e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TFIIE_beta PF02186.10 EMR70495.1 - 1.1e-05 25.3 0.0 4.5e-05 23.3 0.0 2.1 3 0 0 3 3 3 1 TFIIE beta subunit core domain DUF390 PF04094.9 EMR70495.1 - 5.2 4.9 15.2 0.59 8.1 7.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF390) Cellulase PF00150.13 EMR70496.1 - 7.5e-11 41.7 0.4 7.5e-11 41.7 0.3 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.1 EMR70496.1 - 0.0042 17.4 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SecG PF03840.9 EMR70496.1 - 0.045 13.4 0.1 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase SecG subunit P12 PF12669.2 EMR70496.1 - 0.066 13.4 0.2 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF2433 PF10360.4 EMR70497.1 - 8.1e-54 181.4 0.0 1.3e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) DUF2360 PF10152.4 EMR70497.1 - 0.0037 17.5 5.8 0.087 13.1 4.1 2.3 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) ketoacyl-synt PF00109.21 EMR70498.1 - 6e-51 173.3 2.9 9.2e-32 110.4 0.0 3.2 2 1 1 3 3 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMR70498.1 - 1.8e-37 127.7 0.1 4.9e-37 126.3 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EMR70498.1 - 5.8e-25 88.2 0.0 1.1e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EMR70498.1 - 3e-20 72.5 0.0 6.1e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_3 PF07859.8 EMR70498.1 - 7.6e-18 64.8 0.0 7.5e-14 51.8 0.0 2.9 2 0 0 2 2 2 2 alpha/beta hydrolase fold Methyltransf_12 PF08242.7 EMR70498.1 - 5.1e-16 58.9 0.0 2e-15 57.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR70498.1 - 1.9e-15 56.8 1.1 4.4e-15 55.6 0.8 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EMR70498.1 - 5.8e-11 42.3 0.0 3.5e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Abhydrolase_5 PF12695.2 EMR70498.1 - 2.8e-09 36.8 0.3 3.5e-05 23.5 0.0 3.0 2 0 0 2 2 2 2 Alpha/beta hydrolase family Methyltransf_31 PF13847.1 EMR70498.1 - 2.8e-08 33.5 0.0 6.9e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR70498.1 - 6e-07 29.8 0.0 2.6e-05 24.6 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_S9 PF00326.16 EMR70498.1 - 2.9e-06 26.6 0.0 0.00063 19.0 0.0 2.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Methyltransf_25 PF13649.1 EMR70498.1 - 3.5e-06 27.2 0.0 1.3e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR70498.1 - 0.00014 22.4 0.0 0.00078 20.0 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain DUF938 PF06080.7 EMR70498.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.13 EMR70498.1 - 0.085 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EMR70498.1 - 0.2 11.0 0.0 0.39 10.0 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 EMR70498.1 - 0.23 10.8 0.0 0.6 9.5 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase DNA_gyraseB_C PF00986.16 EMR70498.1 - 0.26 11.0 0.0 0.8 9.5 0.0 1.8 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus SRP-alpha_N PF04086.8 EMR70499.1 - 0.57 9.5 8.5 0.62 9.3 5.9 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CMV_1a PF12467.3 EMR70499.1 - 0.82 10.0 6.8 1.1 9.6 4.7 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Glyco_hydro_75 PF07335.6 EMR70500.1 - 4.4e-27 94.8 0.2 7e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DUF3632 PF12311.3 EMR70500.1 - 7.9e-12 45.3 4.1 2.4e-11 43.8 2.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) Abhydrolase_3 PF07859.8 EMR70501.1 - 5.7e-46 156.7 0.0 7.5e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMR70501.1 - 0.0035 16.1 0.6 0.016 13.9 0.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.4 EMR70501.1 - 0.049 12.8 0.5 0.15 11.3 0.4 1.7 1 1 0 1 1 1 0 Esterase PHB depolymerase DUF3025 PF11227.3 EMR70501.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) EXS PF03124.9 EMR70503.1 - 1.9e-42 145.5 5.6 2.5e-42 145.1 3.9 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EMR70503.1 - 1.2e-14 54.7 0.4 1.2e-14 54.7 0.3 2.7 2 1 0 2 2 2 1 SPX domain Nop14 PF04147.7 EMR70503.1 - 0.13 10.1 13.8 0.17 9.8 9.6 1.2 1 0 0 1 1 1 0 Nop14-like family Yip1 PF04893.12 EMR70504.1 - 0.0077 15.7 0.9 1.4 8.4 0.0 2.1 2 0 0 2 2 2 2 Yip1 domain MFS_1 PF07690.11 EMR70505.1 - 6e-16 58.0 7.3 1.1e-13 50.6 1.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4017 PF13209.1 EMR70505.1 - 0.019 14.7 0.9 0.036 13.8 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4017) PepSY_TM_1 PF13172.1 EMR70505.1 - 0.32 10.7 11.8 0.24 11.1 0.2 2.8 3 0 0 3 3 3 0 PepSY-associated TM helix PLA2_B PF01735.13 EMR70506.1 - 9.6e-185 614.4 3.2 1.1e-184 614.1 2.2 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain C2 PF00168.25 EMR70507.1 - 3.2e-19 68.5 0.1 1.3e-09 37.7 0.0 2.6 2 0 0 2 2 2 2 C2 domain UBA PF00627.26 EMR70508.1 - 7.4e-07 28.8 0.2 4.7e-06 26.2 0.0 2.5 3 0 0 3 3 3 1 UBA/TS-N domain DnaJ PF00226.26 EMR70508.1 - 0.0031 17.2 0.9 0.0091 15.7 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain Methyltransf_31 PF13847.1 EMR70509.1 - 3.4e-05 23.4 0.0 3.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR70509.1 - 7.2e-05 23.3 0.0 0.00011 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR70509.1 - 0.00015 22.1 0.0 0.00028 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR70509.1 - 0.00052 19.7 0.0 0.00071 19.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR70509.1 - 0.056 13.9 0.0 0.079 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF1996 PF09362.5 EMR70510.1 - 2.4e-78 263.0 0.0 3.7e-78 262.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) APH PF01636.18 EMR70511.1 - 0.0003 20.5 0.0 0.01 15.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 EMR70511.1 - 0.012 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) L_protein_N PF15518.1 EMR70511.1 - 0.031 13.6 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 L protein N-terminus Sugar_tr PF00083.19 EMR70512.1 - 8.6e-110 367.3 20.2 1.1e-109 367.0 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR70512.1 - 5.8e-19 68.0 36.7 8.7e-14 50.9 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR70512.1 - 0.00017 20.1 1.9 0.00017 20.1 1.3 3.2 2 2 0 3 3 3 2 MFS/sugar transport protein PCI PF01399.22 EMR70514.1 - 0.0014 18.9 0.0 3.7 7.9 0.0 3.3 3 0 0 3 3 3 2 PCI domain TPR_2 PF07719.12 EMR70514.1 - 0.0037 17.0 0.1 0.0077 16.0 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat UQ_con PF00179.21 EMR70515.1 - 1.4e-51 173.5 0.0 1.6e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EMR70515.1 - 8.2e-07 28.8 0.0 9.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EMR70515.1 - 0.031 14.1 0.1 0.062 13.1 0.1 1.6 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.18 EMR70517.1 - 6.8e-90 300.6 0.3 1.2e-89 299.8 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMR70517.1 - 3.7e-38 129.7 0.7 3.7e-38 129.7 0.5 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EMR70517.1 - 0.00024 20.6 1.7 0.00051 19.6 0.4 2.1 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Kinesin PF00225.18 EMR70518.1 - 1.1e-112 376.0 0.1 1.1e-112 376.0 0.1 2.0 2 0 0 2 2 2 1 Kinesin motor domain ERM PF00769.14 EMR70518.1 - 0.0058 16.2 21.4 0.0058 16.2 14.9 3.7 3 1 1 4 4 4 2 Ezrin/radixin/moesin family AA_permease PF00324.16 EMR70520.1 - 7.7e-111 370.7 37.8 9.3e-111 370.4 26.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR70520.1 - 8.9e-19 67.3 40.3 1.2e-18 66.9 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EMR70520.1 - 0.0015 18.2 6.2 0.0015 18.2 4.3 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF1772) UPF0261 PF06792.6 EMR70520.1 - 0.12 10.8 0.1 0.18 10.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Orthoreo_P10 PF07204.6 EMR70520.1 - 0.48 10.2 4.9 0.34 10.6 1.6 2.0 1 1 1 2 2 2 0 Orthoreovirus membrane fusion protein p10 Suc_Fer-like PF06999.7 EMR70521.1 - 1.1e-49 169.4 0.0 1.7e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like FAD_binding_6 PF00970.19 EMR70521.1 - 1.6e-07 31.3 0.0 1e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EMR70521.1 - 0.0028 18.1 0.1 0.052 14.1 0.0 2.8 4 0 0 4 4 4 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EMR70521.1 - 0.19 11.6 0.0 0.61 9.9 0.0 1.9 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DUF500 PF04366.7 EMR70522.1 - 5.9e-35 119.4 0.1 9.7e-35 118.7 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) CoA_binding PF02629.14 EMR70523.1 - 1.3e-28 99.3 4.1 6.5e-28 97.1 0.5 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EMR70523.1 - 9.1e-24 83.7 0.2 1.5e-23 83.0 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EMR70523.1 - 1.8e-08 34.0 0.0 3.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EMR70523.1 - 0.0011 19.0 0.1 0.0059 16.7 0.0 2.2 3 0 0 3 3 3 1 CoA binding domain GFO_IDH_MocA PF01408.17 EMR70523.1 - 0.026 15.0 0.1 0.051 14.0 0.1 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAAA-beta PF15508.1 EMR70524.1 - 2e-19 69.7 0.0 5.9e-19 68.2 0.0 1.8 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF281 PF03436.8 EMR70525.1 - 0.034 14.2 0.5 0.12 12.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF281) PQQ_3 PF13570.1 EMR70525.1 - 5.1 7.4 9.3 9.5 6.6 1.4 4.0 4 0 0 4 4 4 0 PQQ-like domain 5_nucleotid_C PF02872.13 EMR70526.1 - 5.6e-34 117.3 0.3 1.6e-33 115.9 0.1 1.8 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EMR70526.1 - 1.4e-11 44.2 0.2 1e-10 41.3 0.2 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PGA_cap PF09587.5 EMR70526.1 - 0.00076 18.9 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap YmdB PF13277.1 EMR70526.1 - 0.012 14.6 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 YmdB-like protein AAA PF00004.24 EMR70527.1 - 4.4e-41 140.1 0.0 8.4e-41 139.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR70527.1 - 1e-06 28.8 0.1 0.0003 20.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EMR70527.1 - 3.8e-06 26.9 0.0 8.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EMR70527.1 - 1.4e-05 24.2 0.0 2.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EMR70527.1 - 8.7e-05 22.2 0.1 0.0003 20.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMR70527.1 - 0.00019 21.5 1.1 0.0014 18.6 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EMR70527.1 - 0.00049 19.2 0.0 0.0009 18.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EMR70527.1 - 0.0011 18.8 0.2 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EMR70527.1 - 0.0026 17.7 1.7 0.0049 16.8 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EMR70527.1 - 0.0039 17.0 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMR70527.1 - 0.0065 16.2 0.3 0.016 14.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EMR70527.1 - 0.0069 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EMR70527.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EMR70527.1 - 0.011 16.5 1.8 0.012 16.4 0.2 2.1 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EMR70527.1 - 0.011 16.0 0.1 0.028 14.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EMR70527.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EMR70527.1 - 0.014 14.6 1.7 0.21 10.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 EMR70527.1 - 0.016 14.8 0.2 0.34 10.5 0.0 2.6 2 1 1 3 3 3 0 NACHT domain TIP49 PF06068.8 EMR70527.1 - 0.023 13.4 0.0 0.043 12.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus NB-ARC PF00931.17 EMR70527.1 - 0.039 12.8 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EMR70527.1 - 0.046 13.9 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EMR70527.1 - 0.055 12.6 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EMR70527.1 - 0.056 13.0 0.2 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMR70527.1 - 0.077 12.1 0.1 0.43 9.6 0.1 2.0 1 1 1 2 2 2 0 KaiC DUF2075 PF09848.4 EMR70527.1 - 0.14 11.1 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EMR70527.1 - 0.27 10.6 5.5 0.25 10.7 0.3 2.7 2 1 1 3 3 3 0 AAA domain HhH-GPD PF00730.20 EMR70528.1 - 0.029 14.6 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EMR70528.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif MFS_1 PF07690.11 EMR70529.1 - 5.1e-44 150.4 40.9 5.1e-44 150.4 28.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR70529.1 - 3.1e-12 45.8 21.5 2.1e-11 43.1 7.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.13 EMR70530.1 - 4.3e-08 32.3 0.0 5.1e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C2 PF00648.16 EMR70531.1 - 2.9e-51 174.2 0.8 1.9e-35 122.3 0.4 2.5 2 0 0 2 2 2 2 Calpain family cysteine protease Glyco_hydro_3 PF00933.16 EMR70532.1 - 8.2e-74 248.2 0.0 1.4e-73 247.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR70532.1 - 1.1e-42 146.0 0.2 1.2e-41 142.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR70532.1 - 3.8e-24 84.4 0.3 9.8e-24 83.0 0.0 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain Tannase PF07519.6 EMR70533.1 - 1.5e-111 373.4 0.1 1.9e-111 373.0 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EMR70533.1 - 4.2e-07 30.0 0.0 6.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR70533.1 - 1e-05 25.2 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR70533.1 - 0.0034 17.1 0.0 0.073 12.8 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Dyp_perox PF04261.7 EMR70534.1 - 2.1e-08 33.2 0.0 2.9e-07 29.5 0.0 2.3 2 1 0 2 2 2 1 Dyp-type peroxidase family Abhydrolase_6 PF12697.2 EMR70535.1 - 6e-18 65.5 0.0 7.4e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR70535.1 - 4.3e-14 52.6 0.0 5.2e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR70535.1 - 3.1e-08 33.4 0.0 3.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EMR70535.1 - 0.081 12.7 0.5 0.22 11.3 0.0 2.0 2 1 1 3 3 3 0 Putative lysophospholipase adh_short PF00106.20 EMR70536.1 - 6.2e-12 45.7 1.4 0.0012 18.8 1.0 3.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EMR70536.1 - 0.037 13.6 0.1 0.24 11.0 0.2 2.0 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 EMR70537.1 - 4.3e-31 108.0 0.2 5.4e-31 107.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR70537.1 - 2.7e-21 76.4 0.0 3.8e-15 56.3 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR70537.1 - 7.4e-14 51.8 0.0 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMR70537.1 - 0.00011 21.2 0.0 0.00014 20.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EMR70537.1 - 0.14 11.8 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Chitin_bind_3 PF03067.10 EMR70538.1 - 6.4e-05 23.2 0.2 0.00042 20.6 0.1 1.9 1 1 1 2 2 2 1 Chitin binding domain DUF1275 PF06912.6 EMR70539.1 - 0.012 14.8 3.7 0.021 14.0 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) SpoVAB PF13782.1 EMR70539.1 - 0.11 12.4 0.4 0.11 12.4 0.3 1.8 2 0 0 2 2 2 0 Stage V sporulation protein AB TTL PF03133.10 EMR70540.1 - 7.6e-36 123.5 0.0 9e-35 120.0 0.0 2.2 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 EMR70540.1 - 0.00096 18.0 0.0 0.0024 16.7 0.0 1.6 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 EMR70540.1 - 0.0041 16.8 0.0 1.4 8.6 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMR70540.1 - 0.027 13.8 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus p450 PF00067.17 EMR70541.1 - 3.4e-15 55.5 0.0 3.5e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hrs_helical PF12210.3 EMR70541.1 - 0.13 12.5 0.0 0.98 9.7 0.0 2.3 1 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate U79_P34 PF03064.11 EMR70542.1 - 3.2 7.1 8.4 3.3 7.1 5.8 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NmrA PF05368.8 EMR70543.1 - 3.1e-23 82.2 0.0 3.5e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR70543.1 - 2.3e-13 50.5 0.0 3.9e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EMR70543.1 - 0.00012 21.1 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EMR70543.1 - 0.00065 19.2 0.1 0.0055 16.1 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR70543.1 - 0.046 12.4 0.1 0.094 11.3 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EMR70543.1 - 0.048 13.9 0.3 0.14 12.4 0.0 1.9 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EMR70543.1 - 0.052 13.3 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sod_Fe_C PF02777.13 EMR70544.1 - 6.1e-36 122.4 0.6 1e-35 121.7 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EMR70544.1 - 1.6e-33 114.7 1.3 3.9e-33 113.5 0.3 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ank PF00023.25 EMR70545.1 - 2.7e-16 58.4 1.5 8e-12 44.3 0.1 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EMR70545.1 - 3e-16 59.4 0.1 7.9e-11 42.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR70545.1 - 6.5e-14 50.6 0.1 2.7e-08 33.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EMR70545.1 - 7.4e-14 51.8 0.1 1.1e-13 51.3 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMR70545.1 - 5.4e-12 45.5 0.2 1.1e-08 35.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Flexi_CP_N PF08358.5 EMR70545.1 - 0.016 14.9 0.2 0.08 12.7 0.0 2.0 2 0 0 2 2 2 0 Carlavirus coat RVP PF00077.15 EMR70545.1 - 0.098 12.5 0.1 3.4 7.6 0.0 2.2 1 1 1 2 2 2 0 Retroviral aspartyl protease Acetyltransf_1 PF00583.19 EMR70546.1 - 0.0001 22.2 0.0 0.00023 21.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 EMR70546.1 - 0.094 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Rogdi_lz PF10259.4 EMR70547.1 - 0.084 11.9 0.3 0.14 11.2 0.1 1.4 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein YlbD_coat PF14071.1 EMR70547.1 - 0.09 12.8 0.3 1.5 8.9 0.0 2.5 1 1 2 3 3 3 0 Putative coat protein CH PF00307.26 EMR70548.1 - 5.2e-11 42.5 0.0 8.1e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain NDUFA12 PF05071.11 EMR70549.1 - 1.8e-07 31.6 0.8 1.8e-07 31.6 0.6 2.8 2 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Strabismus PF06638.6 EMR70549.1 - 5.2 5.2 8.7 7.1 4.8 6.0 1.1 1 0 0 1 1 1 0 Strabismus protein Acetyltransf_7 PF13508.1 EMR70550.1 - 4.7e-12 45.8 0.0 1.7e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR70550.1 - 4.1e-08 33.1 0.1 1e-07 31.8 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMR70550.1 - 1.6e-05 24.9 0.0 0.00019 21.5 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR70550.1 - 0.0014 18.4 0.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF1180 PF06679.7 EMR70551.1 - 0.041 13.7 0.5 0.07 13.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4658 PF15555.1 EMR70551.1 - 2 8.2 4.1 9.2 6.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4658) SR-25 PF10500.4 EMR70551.1 - 2.2 7.6 6.9 3.2 7.1 4.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Bac_rhodopsin PF01036.13 EMR70552.1 - 2.7e-30 105.3 19.9 3.3e-30 105.0 13.8 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein PHD PF00628.24 EMR70553.1 - 2.1e-08 33.7 8.5 3.6e-08 32.9 5.9 1.4 1 0 0 1 1 1 1 PHD-finger DUF4611 PF15387.1 EMR70553.1 - 0.048 13.8 4.2 12 6.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-RING-like PF08746.6 EMR70553.1 - 0.12 12.4 1.6 0.23 11.4 1.1 1.5 1 0 0 1 1 1 0 RING-like domain Arrestin_N PF00339.24 EMR70554.1 - 1.7e-05 24.7 0.0 4.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain OTU PF02338.14 EMR70556.1 - 5.1e-10 39.9 0.0 1.6e-09 38.3 0.0 1.7 1 1 1 2 2 2 1 OTU-like cysteine protease adh_short PF00106.20 EMR70557.1 - 2.8e-20 72.9 0.1 4e-20 72.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR70557.1 - 1.9e-09 37.4 0.0 2.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR70557.1 - 0.00062 19.8 0.0 0.00093 19.2 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR70557.1 - 0.0017 17.8 0.0 0.0023 17.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Beta-lactamase PF00144.19 EMR70557.1 - 0.018 14.0 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase Eno-Rase_NADH_b PF12242.3 EMR70557.1 - 0.041 13.6 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase BBE PF08031.7 EMR70559.1 - 1.7e-10 40.6 1.1 1.7e-10 40.6 0.8 1.8 2 0 0 2 2 2 1 Berberine and berberine like FAD_binding_4 PF01565.18 EMR70559.1 - 4.5e-08 32.6 3.1 4.5e-08 32.6 2.2 1.9 2 0 0 2 2 2 1 FAD binding domain PI3K_1B_p101 PF10486.4 EMR70561.1 - 0.18 9.3 0.9 0.23 8.9 0.6 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NYN PF01936.13 EMR70562.1 - 0.0001 22.6 0.0 0.0026 18.0 0.0 2.1 1 1 0 1 1 1 1 NYN domain RTA1 PF04479.8 EMR70563.1 - 8.4e-14 51.5 1.5 1.9e-13 50.4 1.0 1.5 1 1 0 1 1 1 1 RTA1 like protein DUF3112 PF11309.3 EMR70563.1 - 0.0065 16.2 1.1 0.0086 15.8 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) DUF3995 PF13160.1 EMR70563.1 - 0.14 12.2 6.2 0.11 12.5 1.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3995) DUF308 PF03729.8 EMR70563.1 - 0.19 11.7 4.6 0.36 10.8 1.7 2.4 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF572 PF04502.8 EMR70564.1 - 2.2e-28 99.4 21.6 5.3e-19 68.5 0.9 2.0 2 0 0 2 2 2 2 Family of unknown function (DUF572) HSCB_C PF07743.8 EMR70564.1 - 1.2 9.6 10.4 0.23 11.9 3.7 2.3 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain EI24 PF07264.6 EMR70565.1 - 0.0043 16.5 7.3 0.077 12.4 5.0 2.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) TP6A_N PF04406.9 EMR70565.1 - 0.15 11.7 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 Type IIB DNA topoisomerase HEAT PF02985.17 EMR70566.1 - 2.5e-19 67.5 8.7 0.0013 18.6 0.0 10.4 10 0 0 10 10 9 5 HEAT repeat HEAT_2 PF13646.1 EMR70566.1 - 6.6e-19 67.9 14.8 5.5e-08 32.9 0.1 7.8 4 3 5 9 9 9 7 HEAT repeats HEAT_EZ PF13513.1 EMR70566.1 - 3.5e-18 65.5 13.0 9.5e-09 35.4 0.1 9.1 7 1 2 9 9 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EMR70566.1 - 2.4e-12 47.0 0.5 0.016 15.6 0.0 7.2 5 1 3 8 8 7 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 EMR70566.1 - 1.9e-09 37.4 0.0 0.02 14.5 0.0 4.9 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 EMR70566.1 - 1.5e-08 34.3 2.5 0.0037 16.6 0.1 5.4 5 1 1 6 6 6 2 CLASP N terminal MMS19_C PF12460.3 EMR70566.1 - 7.1e-08 31.5 0.3 1.9e-05 23.6 0.1 3.6 2 2 1 3 3 3 1 RNAPII transcription regulator C-terminal Proteasom_PSMB PF10508.4 EMR70566.1 - 3.3e-05 22.3 0.1 0.0003 19.2 0.0 2.4 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.15 EMR70566.1 - 0.00013 20.5 6.1 0.024 13.0 0.5 3.9 3 1 1 4 4 4 1 Adaptin N terminal region DUF4042 PF13251.1 EMR70566.1 - 0.0077 15.7 0.0 2 7.8 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4042) V-ATPase_H_N PF03224.9 EMR70566.1 - 0.015 14.4 3.1 0.44 9.6 0.0 2.9 2 1 0 2 2 2 0 V-ATPase subunit H DUF3535 PF12054.3 EMR70566.1 - 0.024 13.2 0.3 0.073 11.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) CAS_CSE1 PF03378.10 EMR70566.1 - 0.031 12.5 0.0 1.6 6.9 0.1 2.9 2 1 0 2 2 2 0 CAS/CSE protein, C-terminus IBN_N PF03810.14 EMR70566.1 - 0.036 13.9 0.3 0.22 11.4 0.0 2.6 2 0 0 2 2 2 0 Importin-beta N-terminal domain UNC45-central PF11701.3 EMR70566.1 - 0.038 13.6 1.7 6.3 6.4 0.0 4.0 4 1 1 5 5 4 0 Myosin-binding striated muscle assembly central Telomere_reg-2 PF10193.4 EMR70566.1 - 0.041 14.1 2.2 0.099 12.9 0.5 2.4 2 0 0 2 2 2 0 Telomere length regulation protein DUF1546 PF07571.8 EMR70566.1 - 0.064 13.3 0.3 7 6.8 0.0 3.8 4 0 0 4 4 3 0 Protein of unknown function (DUF1546) Cohesin_HEAT PF12765.2 EMR70566.1 - 0.077 12.9 0.1 3.2 7.8 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DRIM PF07539.7 EMR70566.1 - 0.13 11.7 2.4 0.18 11.2 0.5 2.1 2 0 0 2 2 2 0 Down-regulated in metastasis FdhE PF04216.7 EMR70566.1 - 0.13 11.9 2.9 0.28 10.8 0.1 2.7 3 0 0 3 3 3 0 Protein involved in formate dehydrogenase formation Arm PF00514.18 EMR70566.1 - 5.1 7.0 13.3 8.8 6.3 0.0 5.4 7 0 0 7 7 4 0 Armadillo/beta-catenin-like repeat Bromodomain PF00439.20 EMR70567.1 - 5e-36 122.4 2.4 1.5e-19 69.7 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EMR70567.1 - 2.8e-16 59.3 2.5 5.3e-16 58.4 0.8 2.1 2 0 0 2 2 2 1 BAH domain SSPI PF14098.1 EMR70567.1 - 0.065 13.1 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Small, acid-soluble spore protein I FmdA_AmdA PF03069.10 EMR70568.1 - 8.4e-148 491.9 0.0 9.8e-148 491.7 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Prenyltransf PF01255.14 EMR70569.1 - 0.00099 18.2 0.0 0.025 13.7 0.0 2.2 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase 2OG-FeII_Oxy_2 PF13532.1 EMR70570.1 - 5.6e-28 98.0 0.0 1e-27 97.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Met_10 PF02475.11 EMR70571.1 - 3.2e-48 163.9 0.0 5.5e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Adaptin_binding PF10199.4 EMR70572.1 - 1e-14 54.9 7.8 6.2e-14 52.4 5.4 2.1 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Cupin_2 PF07883.6 EMR70573.1 - 1.9e-11 43.2 0.4 3.3e-11 42.5 0.2 1.5 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EMR70573.1 - 6e-10 38.7 0.0 7.3e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EMR70573.1 - 0.00044 19.5 0.1 0.0011 18.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 EMR70573.1 - 0.0026 17.4 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.2 EMR70573.1 - 0.0036 16.9 0.1 0.013 15.0 0.1 1.8 1 1 0 2 2 2 1 Cupin GPI PF06560.6 EMR70573.1 - 0.037 13.0 0.0 0.15 11.0 0.0 1.9 2 1 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) DUF4437 PF14499.1 EMR70573.1 - 0.12 11.2 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) zinc_ribbon_6 PF14599.1 EMR70574.1 - 0.22 11.3 1.9 17 5.2 0.1 2.8 2 1 0 2 2 2 0 Zinc-ribbon EFhand_Ca_insen PF08726.5 EMR70574.1 - 4.3 7.3 8.0 5.2 7.1 1.0 2.8 1 1 1 2 2 2 0 Ca2+ insensitive EF hand MgsA_C PF12002.3 EMR70576.1 - 6.1 6.4 6.3 7.4 6.2 3.8 1.4 1 1 0 1 1 1 0 MgsA AAA+ ATPase C terminal Peptidase_M76 PF09768.4 EMR70577.1 - 2.9e-66 222.2 1.9 3.5e-66 221.9 1.3 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EMR70577.1 - 0.045 13.4 5.2 0.023 14.3 1.6 2.0 1 1 0 2 2 2 0 SprT-like family DUF2268 PF10026.4 EMR70577.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Pyr_redox_3 PF13738.1 EMR70578.1 - 3.8e-05 23.8 0.0 0.00084 19.4 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF2040 PF09745.4 EMR70579.1 - 2.1e-39 134.2 21.5 2.1e-39 134.2 14.9 3.7 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Abhydrolase_4 PF08386.5 EMR70580.1 - 5.2e-16 58.3 0.0 1.1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EMR70580.1 - 6.5e-12 45.5 0.0 1.3e-11 44.5 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR70580.1 - 1.3e-08 35.0 5.6 6.6e-08 32.7 3.9 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR70580.1 - 1.8e-05 24.5 0.0 0.00016 21.4 0.0 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3129 PF11327.3 EMR70581.1 - 8.3e-29 100.7 10.5 8.3e-29 100.7 7.3 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) MFS_1 PF07690.11 EMR70582.1 - 9.5e-33 113.3 26.0 1.4e-32 112.7 18.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1616 PF07760.6 EMR70582.1 - 0.45 9.6 7.3 0.19 10.8 3.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) zf-Tim10_DDP PF02953.10 EMR70583.1 - 1.3e-21 75.6 3.0 1.5e-21 75.4 2.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PMEI PF04043.10 EMR70583.1 - 0.017 15.0 0.1 0.018 14.9 0.1 1.1 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Ins_beta PF03488.9 EMR70583.1 - 0.033 13.9 0.6 0.054 13.3 0.4 1.3 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type DUF3283 PF11686.3 EMR70583.1 - 0.089 12.6 0.2 0.29 10.9 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3283) Hydrolase_3 PF08282.7 EMR70584.1 - 6.4e-11 42.3 0.0 9.9e-07 28.5 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase PMM PF03332.8 EMR70584.1 - 6.3e-10 38.9 0.0 7.9e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.8 EMR70584.1 - 0.00072 18.9 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 EMR70584.1 - 0.011 16.1 0.0 0.014 15.8 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EMR70584.1 - 0.062 13.5 0.0 5.5 7.1 0.0 2.6 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase ISN1 PF06437.6 EMR70584.1 - 0.1 11.2 0.0 0.59 8.7 0.0 1.9 2 0 0 2 2 2 0 IMP-specific 5'-nucleotidase zf-primase PF09329.6 EMR70585.1 - 0.02 14.4 0.3 0.045 13.3 0.2 1.5 1 0 0 1 1 1 0 Primase zinc finger Stb3 PF10330.4 EMR70585.1 - 0.025 14.2 0.5 0.064 12.9 0.3 1.6 1 0 0 1 1 1 0 Putative Sin3 binding protein Y_Y_Y PF07495.8 EMR70585.1 - 0.16 11.7 1.0 0.38 10.5 0.7 1.6 1 0 0 1 1 1 0 Y_Y_Y domain ABC_tran PF00005.22 EMR70586.1 - 5.7e-26 91.4 0.0 9.3e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EMR70586.1 - 5.9e-05 22.3 0.1 0.00011 21.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EMR70586.1 - 0.00011 22.3 0.1 0.0071 16.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMR70586.1 - 0.0011 18.4 0.0 0.029 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EMR70586.1 - 0.01 15.3 1.1 0.023 14.1 0.8 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EMR70586.1 - 0.021 14.2 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EMR70586.1 - 0.037 13.5 0.2 0.078 12.4 0.2 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EMR70586.1 - 0.07 12.9 0.1 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Dynamin family DUF87 PF01935.12 EMR70586.1 - 0.093 12.5 1.1 0.17 11.7 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 SbcCD_C PF13558.1 EMR70586.1 - 0.1 12.5 0.0 0.35 10.8 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EMR70586.1 - 0.13 13.0 0.0 0.31 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EMR70586.1 - 0.18 10.6 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein IIGP PF05049.8 EMR70586.1 - 0.2 10.4 0.2 0.3 9.8 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Septin PF00735.13 EMR70586.1 - 0.23 10.4 0.1 0.36 9.8 0.1 1.2 1 0 0 1 1 1 0 Septin UPF0113 PF03657.8 EMR70588.1 - 6.9e-05 22.5 0.0 9.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 EMR70588.1 - 0.02 14.9 0.0 0.066 13.2 0.0 1.9 2 1 0 2 2 2 0 pre-rRNA processing and ribosome biogenesis GST_C_2 PF13410.1 EMR70590.1 - 0.062 13.2 0.1 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain PM0188 PF11477.3 EMR70590.1 - 0.22 10.2 0.1 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Sialyltransferase PMO188 Gag_spuma PF03276.9 EMR70590.1 - 1.5 7.0 13.8 2.5 6.3 9.5 1.3 1 0 0 1 1 1 0 Spumavirus gag protein Asparaginase PF00710.15 EMR70592.1 - 1.9e-40 138.7 0.0 2.3e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Asparaginase Fungal_lectin PF07938.7 EMR70593.1 - 0.01 15.1 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Fungal fucose-specific lectin MMS1_N PF10433.4 EMR70593.1 - 0.15 10.1 0.0 0.18 9.8 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Glyco_hydro_7 PF00840.15 EMR70594.1 - 8.8e-179 594.3 14.6 1e-178 594.1 10.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 PsiE PF06146.7 EMR70595.1 - 0.077 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Phosphate-starvation-inducible E UCH PF00443.24 EMR70596.1 - 1.2e-28 100.0 0.1 2e-28 99.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 EMR70596.1 - 7.6e-25 87.1 0.0 1.2e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 EMR70596.1 - 2.5e-12 46.8 0.0 4.8e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.20 EMR70597.1 - 3.6e-69 232.7 0.0 4.5e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR70597.1 - 2.3e-42 144.8 0.0 3.1e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR70597.1 - 5e-07 28.9 0.0 9.8e-07 28.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMR70597.1 - 0.00037 19.6 0.0 0.00062 18.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMR70597.1 - 0.018 14.4 0.0 0.11 11.8 0.0 1.9 1 1 1 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.4 EMR70597.1 - 0.023 14.0 0.0 0.042 13.1 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EMR70597.1 - 0.047 13.4 0.1 0.098 12.3 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1034 PF06280.7 EMR70597.1 - 0.1 12.9 0.4 0.2 12.0 0.3 1.4 1 0 0 1 1 1 0 Fn3-like domain (DUF1034) Seadorna_VP7 PF07387.6 EMR70597.1 - 0.19 10.5 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SNF2_N PF00176.18 EMR70599.1 - 5.6e-74 248.6 0.0 7.5e-74 248.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMR70599.1 - 1e-14 54.1 0.0 2.6e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EMR70599.1 - 8.5e-06 25.7 12.3 1.8e-05 24.6 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMR70599.1 - 0.00037 20.0 12.3 0.00074 19.1 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EMR70599.1 - 0.00054 19.8 0.0 0.0016 18.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 EMR70599.1 - 0.0025 17.4 10.3 0.0045 16.6 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMR70599.1 - 0.0067 16.2 12.1 0.014 15.2 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EMR70599.1 - 0.075 12.7 11.2 0.17 11.6 7.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Glyco_transf_36 PF06165.6 EMR70600.1 - 2.8e-20 72.1 0.0 6.4e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 36 GT36_AF PF06205.6 EMR70600.1 - 5.5e-08 32.4 0.0 1.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase 36 associated family DUF608 PF04685.8 EMR70600.1 - 0.0017 17.1 0.1 0.0031 16.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 DUF2688 PF10892.3 EMR70600.1 - 0.032 13.9 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) p450 PF00067.17 EMR70602.1 - 1.6e-72 244.5 0.0 2e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_kinase PF00696.23 EMR70603.1 - 9.1e-39 133.4 2.5 1.3e-38 132.9 1.7 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EMR70603.1 - 6.9e-15 54.5 0.1 2.2e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 PUA domain 2OG-FeII_Oxy PF03171.15 EMR70604.1 - 1.1e-10 41.6 0.0 3.5e-10 40.0 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMR70604.1 - 1.6e-09 38.3 0.0 3e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF3595 PF12166.3 EMR70604.1 - 0.2 10.4 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) GTP_EFTU PF00009.22 EMR70605.1 - 1.8e-21 76.4 0.0 3.3e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EMR70605.1 - 1.3e-14 54.1 0.0 3.4e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EMR70605.1 - 3.6e-10 39.8 2.6 2.8e-09 36.9 1.5 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Miro PF08477.8 EMR70605.1 - 0.002 18.5 0.1 0.023 15.2 0.1 2.6 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EMR70605.1 - 0.0029 17.5 0.1 0.0068 16.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMR70605.1 - 0.093 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Dynamin family DUF258 PF03193.11 EMR70605.1 - 0.095 11.8 0.4 0.21 10.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 GTP_EFTU_D4 PF14578.1 EMR70605.1 - 0.3 10.7 3.1 0.15 11.7 0.2 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 AAA PF00004.24 EMR70606.1 - 5e-48 162.6 0.0 3.5e-41 140.4 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMR70606.1 - 1.1e-06 28.7 0.2 4.2e-05 23.6 0.0 3.3 3 1 0 4 4 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EMR70606.1 - 8.4e-06 25.3 0.0 0.00019 20.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EMR70606.1 - 2.6e-05 24.2 0.0 8e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EMR70606.1 - 0.00017 21.7 0.1 0.01 15.9 0.1 2.8 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EMR70606.1 - 0.00026 21.0 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 EMR70606.1 - 0.00037 20.2 0.0 0.0014 18.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EMR70606.1 - 0.0014 19.4 0.1 0.039 14.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMR70606.1 - 0.0021 17.7 0.0 0.082 12.6 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 EMR70606.1 - 0.0028 16.4 0.0 0.0047 15.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 EMR70606.1 - 0.0075 16.4 0.0 0.035 14.2 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 EMR70606.1 - 0.013 15.4 0.0 0.046 13.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain Bromodomain PF00439.20 EMR70606.1 - 0.014 15.2 0.0 0.051 13.5 0.0 1.9 1 0 0 1 1 1 0 Bromodomain AAA_14 PF13173.1 EMR70606.1 - 0.027 14.3 0.0 0.081 12.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EMR70606.1 - 0.042 14.1 0.0 0.042 14.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 EMR70606.1 - 0.049 12.7 0.2 0.11 11.5 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EMR70606.1 - 0.05 12.6 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EMR70606.1 - 0.063 12.9 0.1 0.27 10.8 0.1 2.2 1 1 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EMR70606.1 - 0.082 12.3 0.0 2.4 7.5 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF2115 PF09888.4 EMR70606.1 - 0.71 9.9 1.4 1.1 9.3 0.2 1.9 2 0 0 2 2 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF4604 PF15377.1 EMR70607.1 - 1e-23 84.3 11.0 1.4e-23 83.9 7.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) RR_TM4-6 PF06459.7 EMR70607.1 - 4.5 7.0 5.4 5.9 6.6 3.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UbiA PF01040.13 EMR70608.1 - 8.6e-23 80.8 15.5 1.2e-22 80.3 10.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family UPF0081 PF03652.10 EMR70609.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) LDB19 PF13002.2 EMR70610.1 - 1.3e-38 132.4 0.2 2.4e-38 131.5 0.2 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EMR70610.1 - 0.044 13.6 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Metallopep PF12044.3 EMR70611.1 - 5.9e-94 314.9 0.0 7.6e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Arginase PF00491.16 EMR70612.1 - 1.3e-67 228.0 0.1 1.5e-67 227.8 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EMR70612.1 - 0.081 13.1 0.1 0.14 12.3 0.1 1.4 1 1 0 1 1 1 0 UPF0489 domain Trp_syntA PF00290.15 EMR70612.1 - 0.12 10.9 0.0 0.58 8.6 0.0 1.8 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Chs3p PF12271.3 EMR70613.1 - 4.8e-135 449.2 13.3 5.6e-135 448.9 9.2 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 EMR70613.1 - 0.0082 16.0 3.1 0.0082 16.0 2.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3382) AA_permease PF00324.16 EMR70614.1 - 4.1e-105 351.8 42.2 5.1e-105 351.5 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR70614.1 - 1.9e-28 99.1 41.7 2.6e-28 98.7 28.9 1.2 1 0 0 1 1 1 1 Amino acid permease NOC3p PF07540.6 EMR70615.1 - 8.9e-32 109.2 0.1 4.6e-31 106.9 0.1 2.3 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 EMR70615.1 - 8.9e-25 87.0 0.0 9.6e-24 83.6 0.0 2.5 2 0 0 2 2 2 1 CBF/Mak21 family EF-hand_1 PF00036.27 EMR70616.1 - 2e-18 64.2 12.8 2.4e-07 29.5 0.6 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EMR70616.1 - 1.5e-14 53.8 5.5 8.3e-13 48.2 0.8 2.2 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EMR70616.1 - 1.1e-13 49.7 7.8 1.1e-06 27.6 0.2 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EMR70616.1 - 1.9e-13 49.0 3.8 7.4e-05 22.3 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 EMR70616.1 - 1.8e-12 46.6 10.0 1e-05 25.0 0.8 3.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EMR70616.1 - 2.8e-06 27.0 7.2 0.00077 19.1 0.4 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EMR70616.1 - 4.3e-05 23.4 0.0 5.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EMR70616.1 - 0.024 14.5 0.0 0.59 10.0 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain Peptidase_M22 PF00814.20 EMR70618.1 - 1.9e-77 260.3 0.0 2.3e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Pkinase PF00069.20 EMR70619.1 - 4.7e-63 212.7 0.0 5.7e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR70619.1 - 3.2e-28 98.5 0.0 4.4e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR70619.1 - 0.048 12.6 0.0 0.096 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like EPL1 PF10513.4 EMR70620.1 - 4.5e-24 85.5 4.9 4.5e-24 85.5 3.4 2.6 2 1 0 2 2 2 1 Enhancer of polycomb-like SpecificRecomb PF10136.4 EMR70621.1 - 0.095 10.7 1.0 0.11 10.5 0.7 1.1 1 0 0 1 1 1 0 Site-specific recombinase FCH PF00611.18 EMR70621.1 - 0.1 12.7 1.4 0.15 12.2 0.9 1.4 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF1664 PF07889.7 EMR70621.1 - 1.2 8.9 4.2 1.2 8.9 1.6 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Glyco_hydro_61 PF03443.9 EMR70622.1 - 4.5e-69 232.5 0.0 5.1e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 G-patch PF01585.18 EMR70623.1 - 2e-06 27.4 0.0 1.2e-05 24.9 0.0 2.4 1 1 0 1 1 1 1 G-patch domain MIP-T3 PF10243.4 EMR70623.1 - 0.0049 15.3 62.7 0.0068 14.9 43.5 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 EMR70623.1 - 4.2 5.5 34.7 6.4 4.9 24.1 1.2 1 0 0 1 1 1 0 Transmembrane protein AA_permease PF00324.16 EMR70624.1 - 8.2e-127 423.4 50.8 9.6e-127 423.2 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR70624.1 - 6.7e-33 113.8 56.5 9e-33 113.4 39.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3500 PF12006.3 EMR70625.1 - 1.4e-102 342.8 0.0 1.7e-102 342.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) DOG1 PF14144.1 EMR70625.1 - 2 8.5 4.0 53 3.9 0.2 3.7 3 1 0 3 3 3 0 Seed dormancy control RmlD_sub_bind PF04321.12 EMR70627.1 - 1.5e-14 53.6 0.0 3.7e-14 52.3 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EMR70627.1 - 1.5e-13 50.7 0.0 3e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMR70627.1 - 0.00027 20.8 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EMR70627.1 - 0.00045 19.1 0.0 0.00084 18.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMR70627.1 - 0.013 14.2 0.0 0.11 11.2 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EMR70627.1 - 0.025 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.7 EMR70627.1 - 0.081 11.8 0.0 0.45 9.3 0.0 1.9 1 1 1 2 2 2 0 Male sterility protein Inhibitor_I53 PF11714.3 EMR70628.1 - 1.1 9.3 4.2 2.6 8.0 2.3 2.1 1 1 0 1 1 1 0 Thrombin inhibitor Madanin LUC7 PF03194.10 EMR70628.1 - 6.6 6.1 10.1 1e+02 2.2 7.1 2.3 1 1 0 1 1 1 0 LUC7 N_terminus MFS_1 PF07690.11 EMR70629.1 - 6e-37 127.1 43.0 6.6e-33 113.8 16.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR70629.1 - 3.8e-14 52.1 13.3 3.8e-14 52.1 9.2 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter RseC_MucC PF04246.7 EMR70629.1 - 0.39 10.2 5.7 1.7 8.2 1.1 2.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC OATP PF03137.15 EMR70629.1 - 0.68 7.9 7.6 0.1 10.6 0.9 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family GATase PF00117.23 EMR70631.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Kv2channel PF03521.9 EMR70632.1 - 0.04 13.3 0.4 0.058 12.8 0.3 1.2 1 0 0 1 1 1 0 Kv2 voltage-gated K+ channel Fungal_lectin PF07938.7 EMR70633.1 - 0.0015 17.8 1.3 0.047 12.9 0.0 2.3 1 1 1 2 2 2 2 Fungal fucose-specific lectin DPPIV_N PF00930.16 EMR70634.1 - 1.4e-107 359.3 0.3 1.8e-107 358.9 0.2 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EMR70634.1 - 2.7e-53 180.3 2.8 4.5e-53 179.6 1.9 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMR70634.1 - 1.1e-07 31.6 0.1 2.2e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR70634.1 - 0.00021 21.2 0.3 0.0045 16.8 0.2 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EMR70634.1 - 0.00026 20.5 2.5 0.004 16.6 0.9 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EMR70634.1 - 0.14 11.4 0.1 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Polysacc_deac_1 PF01522.16 EMR70635.1 - 3.7e-16 58.8 0.0 7.2e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EMR70635.1 - 0.0065 15.9 0.1 0.015 14.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) ThuA PF06283.6 EMR70635.1 - 0.069 12.8 0.1 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Trehalose utilisation SpoIIIAH PF12685.2 EMR70639.1 - 0.05 13.0 0.7 0.078 12.4 0.5 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF4398 PF14346.1 EMR70641.1 - 0.03 14.3 0.1 0.058 13.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) PhageMin_Tail PF10145.4 EMR70641.1 - 0.084 12.5 0.1 0.18 11.4 0.1 1.6 1 1 0 1 1 1 0 Phage-related minor tail protein TMA7 PF09072.5 EMR70641.1 - 4.3 7.8 7.2 16 6.0 1.8 2.9 2 1 0 2 2 2 0 Translation machinery associated TMA7 FtsQ PF03799.10 EMR70642.1 - 0.093 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Cell division protein FtsQ Carb_kinase PF01256.12 EMR70643.1 - 3.3e-54 183.7 0.0 5.1e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EMR70643.1 - 0.022 13.9 0.1 0.046 12.8 0.1 1.6 1 1 0 1 1 1 0 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 EMR70643.1 - 0.026 13.6 0.0 0.054 12.6 0.0 1.6 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase ATP-synt_ab PF00006.20 EMR70644.1 - 5.2e-64 215.6 0.0 8.1e-39 133.3 0.0 2.3 1 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMR70644.1 - 7.3e-26 90.8 0.7 1.6e-25 89.7 0.2 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMR70644.1 - 1e-15 57.6 2.5 2.5e-15 56.4 1.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EMR70644.1 - 0.0042 16.9 1.3 0.0094 15.8 0.7 1.8 2 0 0 2 2 2 1 HAS barrel domain AAA_25 PF13481.1 EMR70644.1 - 0.068 12.5 0.0 0.18 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Utp8 PF10395.4 EMR70644.1 - 0.12 10.6 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 Utp8 family DAO PF01266.19 EMR70645.1 - 6.8e-24 84.4 0.0 7.8e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase U79_P34 PF03064.11 EMR70646.1 - 1.3 8.4 14.4 0.026 14.0 4.2 2.0 2 0 0 2 2 2 0 HSV U79 / HCMV P34 CAF-1_p150 PF11600.3 EMR70646.1 - 6 6.1 39.0 0.14 11.4 19.5 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DNA_Packaging PF11053.3 EMR70647.1 - 0.14 11.7 0.0 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Terminase DNA packaging enzyme UBN_AB PF14075.1 EMR70647.1 - 1.3 8.6 7.8 2.1 7.9 5.4 1.3 1 0 0 1 1 1 0 Ubinuclein conserved middle domain DUF2175 PF09943.4 EMR70647.1 - 2 8.5 7.6 4.8 7.2 5.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Transferase PF02458.10 EMR70648.1 - 1.3e-36 125.9 0.0 8.9e-28 96.8 0.0 2.0 2 0 0 2 2 2 2 Transferase family NmrA PF05368.8 EMR70649.1 - 1.6e-21 76.6 0.0 2.2e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR70649.1 - 2.7e-16 60.1 0.2 4.3e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR70649.1 - 7.5e-06 25.5 0.5 0.0002 20.8 0.4 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR70649.1 - 0.0032 16.4 0.0 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 EMR70649.1 - 0.021 13.8 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase AAA_7 PF12775.2 EMR70649.1 - 0.023 13.7 0.0 0.22 10.5 0.0 2.1 1 1 1 2 2 2 0 P-loop containing dynein motor region D3 RmlD_sub_bind PF04321.12 EMR70649.1 - 0.029 13.2 0.1 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.15 EMR70649.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EMR70649.1 - 0.096 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 EMR70649.1 - 0.11 12.2 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Rsm22 PF09243.5 EMR70652.1 - 1.5e-30 106.2 0.0 3.5e-29 101.6 0.0 2.7 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Thioredoxin PF00085.15 EMR70652.1 - 8.2e-26 89.7 0.0 1.5e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Methyltransf_23 PF13489.1 EMR70652.1 - 3.5e-06 26.8 0.0 7.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Thioredoxin_8 PF13905.1 EMR70652.1 - 3.7e-06 26.9 0.0 9.6e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Methyltransf_18 PF12847.2 EMR70652.1 - 0.00056 20.4 0.3 0.021 15.3 0.1 3.2 3 1 0 3 3 3 1 Methyltransferase domain Thioredoxin_7 PF13899.1 EMR70652.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EMR70652.1 - 0.0015 18.7 0.0 0.0046 17.1 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Methyltransf_12 PF08242.7 EMR70652.1 - 0.0053 17.1 0.1 0.038 14.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain AhpC-TSA PF00578.16 EMR70652.1 - 0.02 14.5 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 EMR70652.1 - 0.034 13.6 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Redoxin NodS PF05401.6 EMR70652.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Thioredoxin_4 PF13462.1 EMR70652.1 - 0.7 9.8 3.4 0.91 9.5 0.1 2.2 2 1 1 3 3 2 0 Thioredoxin Glyco_transf_90 PF05686.7 EMR70654.1 - 1.8e-11 43.3 1.0 2.1e-08 33.2 0.0 2.9 3 0 0 3 3 3 3 Glycosyl transferase family 90 PhyH PF05721.8 EMR70655.1 - 4e-16 59.6 0.0 5.9e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) p450 PF00067.17 EMR70656.1 - 4.6e-36 124.3 0.0 6.3e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EMR70657.1 - 1.6e-13 50.3 0.0 2.7e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR70657.1 - 0.0003 20.5 0.1 0.0034 17.1 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EMR70657.1 - 0.0022 18.8 0.0 0.0041 18.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Amidohydro_2 PF04909.9 EMR70658.1 - 3.7e-09 36.5 4.3 3.8e-08 33.2 3.0 2.1 1 1 0 1 1 1 1 Amidohydrolase Cupin_2 PF07883.6 EMR70659.1 - 4.1e-10 39.0 0.1 4.1e-10 39.0 0.1 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EMR70659.1 - 2.1e-05 23.9 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EMR70659.1 - 0.0032 17.1 0.1 0.0057 16.3 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain JmjC PF02373.17 EMR70659.1 - 0.008 16.4 0.1 0.07 13.3 0.1 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.6 EMR70659.1 - 0.051 12.6 0.0 0.086 11.8 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) FAD_binding_3 PF01494.14 EMR70660.1 - 3.3e-15 55.9 0.1 1.3e-06 27.7 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR70660.1 - 0.0014 17.6 0.3 0.94 8.3 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR70660.1 - 0.0027 17.7 0.0 0.0075 16.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR70660.1 - 0.035 13.9 0.0 0.12 12.2 0.0 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1860 PF08949.5 EMR70660.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) TRI5 PF06330.6 EMR70663.1 - 4.5e-15 55.1 0.0 6.1e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Abhydrolase_1 PF00561.15 EMR70664.1 - 2.4e-15 56.7 0.3 1.4e-14 54.2 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EMR70664.1 - 4.2e-08 33.0 0.0 9e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EMR70664.1 - 0.00015 21.7 0.0 0.0005 20.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 EMR70665.1 - 2.9e-62 210.7 0.0 1.6e-42 145.5 0.1 2.8 1 1 1 2 2 2 2 Cytochrome P450 Caps_synth PF05704.7 EMR70666.1 - 1.3e-13 50.8 0.0 2.4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EMR70666.1 - 2.2e-05 24.7 0.1 5e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif p450 PF00067.17 EMR70667.1 - 1.8e-43 148.7 0.0 8.8e-43 146.4 0.0 1.8 1 1 1 2 2 2 1 Cytochrome P450 F-box-like PF12937.2 EMR70667.1 - 0.0002 21.0 0.0 0.00062 19.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EMR70667.1 - 0.028 14.1 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain F-box PF00646.28 EMR70667.1 - 0.053 13.1 0.1 0.2 11.3 0.0 1.9 1 0 0 1 1 1 0 F-box domain HET PF06985.6 EMR70668.1 - 9.5e-20 71.1 0.0 4.7e-16 59.2 0.1 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) CHCH PF06747.8 EMR70669.1 - 4.1e-10 39.3 15.6 6.1e-09 35.5 4.9 2.5 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 EMR70669.1 - 0.00046 19.8 12.5 0.04 13.6 0.2 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EMR70669.1 - 0.78 9.8 7.7 0.7 9.9 0.9 2.7 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EMR70669.1 - 4 7.5 12.7 7.6 6.6 0.5 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.11 EMR70669.1 - 5.3 7.0 8.8 5.9 6.9 4.7 2.2 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein GDC-P PF02347.11 EMR70670.1 - 3.2e-170 566.4 0.0 2.7e-155 517.2 0.0 2.7 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 EMR70670.1 - 3.5e-07 29.2 0.0 0.0026 16.5 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 EMR70670.1 - 2.7e-06 26.7 0.0 5.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EMR70670.1 - 0.019 14.0 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family B12-binding PF02310.14 EMR70670.1 - 0.036 13.9 0.4 13 5.6 0.0 3.8 4 0 0 4 4 4 0 B12 binding domain Nup54 PF13874.1 EMR70671.1 - 1.6e-42 144.4 0.9 1.6e-42 144.4 0.6 2.2 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EMR70671.1 - 0.00034 20.8 40.2 0.0019 18.3 27.8 2.0 1 1 0 1 1 1 1 Nucleoporin FG repeat region DUF948 PF06103.6 EMR70671.1 - 0.023 14.5 1.9 4 7.3 0.2 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) T4_gp9_10 PF07880.6 EMR70671.1 - 0.032 13.2 0.7 0.053 12.5 0.5 1.2 1 0 0 1 1 1 0 Bacteriophage T4 gp9/10-like protein HTH_39 PF14090.1 EMR70671.1 - 0.057 12.8 0.2 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain V-SNARE_C PF12352.3 EMR70671.1 - 0.063 13.3 2.5 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus NPV_P10 PF05531.7 EMR70671.1 - 0.082 13.1 5.5 12 6.2 0.1 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Myb_DNA-bind_4 PF13837.1 EMR70671.1 - 0.19 11.8 1.4 2.1 8.5 0.2 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DivIVA PF05103.8 EMR70671.1 - 2.9 7.9 10.2 0.072 13.1 0.7 2.6 2 1 1 3 3 3 0 DivIVA protein NYD-SP28_assoc PF14775.1 EMR70671.1 - 6.9 6.4 11.2 0.74 9.5 1.2 3.1 3 0 0 3 3 3 0 Sperm tail C-terminal domain Fib_alpha PF08702.5 EMR70671.1 - 7.6 6.6 11.5 0.91 9.6 0.7 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family bZIP_1 PF00170.16 EMR70671.1 - 8.1 6.4 10.5 7.4 6.6 0.2 3.8 3 1 1 4 4 4 0 bZIP transcription factor IncA PF04156.9 EMR70671.1 - 8.7 5.8 13.7 0.52 9.8 1.2 2.8 3 0 0 3 3 3 0 IncA protein OmpH PF03938.9 EMR70671.1 - 8.7 6.2 19.2 34 4.3 11.2 2.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Tape_meas_lam_C PF09718.5 EMR70672.1 - 0.0023 17.8 0.1 0.0045 16.8 0.1 1.5 1 0 0 1 1 1 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) MR_MLE PF01188.16 EMR70672.1 - 0.11 13.0 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain ADH_N PF08240.7 EMR70673.1 - 4e-06 26.5 1.5 5.7e-05 22.8 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR70673.1 - 0.0017 17.8 0.3 0.0039 16.7 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_3 PF07859.8 EMR70674.1 - 8.2e-34 117.0 0.0 1.5e-33 116.1 0.0 1.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.7 EMR70674.1 - 0.00054 18.5 0.0 0.00072 18.1 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.2 EMR70674.1 - 0.003 17.3 0.0 0.0034 17.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR70674.1 - 0.017 14.3 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family tRNA-synt_1e PF01406.14 EMR70674.1 - 0.061 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DLH PF01738.13 EMR70674.1 - 0.098 11.9 0.1 0.23 10.7 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EMR70674.1 - 0.14 11.5 0.1 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Cytochrom_C1 PF02167.10 EMR70675.1 - 4e-81 271.8 0.0 4.8e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EMR70675.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Pyrophosphatase PF00719.14 EMR70676.1 - 4.6e-52 175.5 0.1 5.9e-52 175.2 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF3436 PF11918.3 EMR70676.1 - 0.28 11.4 1.8 11 6.3 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3436) F_bP_aldolase PF01116.15 EMR70677.1 - 4.7e-78 262.1 0.0 5.3e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Pro_isomerase PF00160.16 EMR70678.1 - 9.3e-50 168.8 0.2 2.6e-49 167.3 0.1 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EMR70678.1 - 2.4e-16 58.9 0.3 1.9e-08 33.8 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Sugar_tr PF00083.19 EMR70679.1 - 4.7e-23 81.4 9.6 5.9e-23 81.1 6.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR70679.1 - 4.4e-05 22.3 15.6 6.2e-05 21.8 10.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2834 PF11196.3 EMR70680.1 - 0.074 13.2 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) Como_LCP PF02247.11 EMR70680.1 - 0.19 10.0 0.1 0.3 9.4 0.1 1.2 1 0 0 1 1 1 0 Large coat protein Fungal_lectin PF07938.7 EMR70682.1 - 8.5e-19 67.9 0.0 1.4e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Fungal fucose-specific lectin HhH-GPD PF00730.20 EMR70683.1 - 7e-05 23.0 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein FPN1 PF06963.7 EMR70684.1 - 4.2e-71 239.5 10.2 4.2e-45 153.9 2.5 2.0 2 0 0 2 2 2 2 Ferroportin1 (FPN1) DUF4131 PF13567.1 EMR70684.1 - 5.4 6.3 12.2 0.04 13.3 0.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Ion_trans PF00520.26 EMR70685.1 - 9.6e-80 266.5 60.8 3.4e-36 124.3 1.9 6.1 4 2 1 5 5 5 5 Ion transport protein Sec20 PF03908.8 EMR70686.1 - 2.1e-16 59.3 0.5 2.1e-16 59.3 0.4 2.7 4 0 0 4 4 4 1 Sec20 DASH_Dam1 PF08653.5 EMR70686.1 - 0.0012 18.5 3.3 0.035 13.8 0.1 2.7 3 0 0 3 3 3 2 DASH complex subunit Dam1 NPV_P10 PF05531.7 EMR70686.1 - 3.5 7.9 8.7 2.3e+02 2.0 3.8 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF342 PF03961.8 EMR70686.1 - 4.5 5.5 6.9 0.28 9.5 0.8 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF342) DUF4407 PF14362.1 EMR70686.1 - 6.3 5.6 12.7 11 4.8 7.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Git3 PF11710.3 EMR70687.1 - 5.5e-18 65.2 12.1 8.9e-18 64.5 8.4 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EMR70687.1 - 1e-08 34.6 9.8 1.5e-08 34.1 6.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 EMR70687.1 - 9.5e-06 25.2 0.0 2.6e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 EMR70687.1 - 0.00045 19.2 9.1 0.0008 18.3 6.3 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor adh_short_C2 PF13561.1 EMR70688.1 - 9.8e-28 97.5 0.0 1.1e-27 97.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR70688.1 - 1.6e-25 89.9 3.9 2.1e-25 89.5 2.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR70688.1 - 1.9e-11 43.9 2.6 2.7e-11 43.4 1.8 1.1 1 0 0 1 1 1 1 KR domain DAHP_synth_1 PF00793.15 EMR70690.1 - 4.7e-94 314.0 0.0 5.9e-94 313.7 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family PHD PF00628.24 EMR70691.1 - 3.3e-09 36.2 9.0 7.5e-09 35.1 6.2 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EMR70691.1 - 0.0053 16.0 5.3 0.011 14.9 3.7 1.5 1 0 0 1 1 1 1 PHD-finger Peptidase_C15 PF01470.12 EMR70692.1 - 1.5e-09 38.0 0.0 7.3e-09 35.7 0.0 2.0 1 1 1 2 2 2 1 Pyroglutamyl peptidase Dus PF01207.12 EMR70693.1 - 8.5e-46 156.1 0.3 2.8e-45 154.5 0.2 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Zn_clus PF00172.13 EMR70694.1 - 0.032 14.1 9.6 0.057 13.3 6.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP1 PF07218.6 EMR70694.1 - 2.3 6.2 5.7 2.5 6.0 0.0 2.6 3 0 0 3 3 3 0 Rhoptry-associated protein 1 (RAP-1) Oxidored_FMN PF00724.15 EMR70695.1 - 4.9e-72 242.7 0.0 4.7e-69 232.9 0.0 2.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Acetyltransf_1 PF00583.19 EMR70698.1 - 0.00027 20.8 0.0 0.00048 20.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR70698.1 - 0.0027 17.8 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR70698.1 - 0.003 17.6 0.2 0.031 14.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR70698.1 - 0.027 14.3 0.2 1 9.1 0.0 2.6 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain HMG_box PF00505.14 EMR70699.1 - 6.3e-10 39.1 1.1 1.4e-09 38.0 0.8 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMR70699.1 - 0.00099 19.4 0.5 0.0031 17.8 0.3 1.9 1 0 0 1 1 1 1 HMG-box domain RNA_ligase PF09414.5 EMR70700.1 - 3.5e-12 46.5 0.0 5.2e-11 42.6 0.0 2.3 1 1 0 1 1 1 1 RNA ligase DUF1541 PF07563.6 EMR70700.1 - 0.16 11.6 0.2 0.37 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1541) Aldo_ket_red PF00248.16 EMR70701.1 - 2.6e-48 164.2 0.0 3.2e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PAS_3 PF08447.6 EMR70701.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold RR_TM4-6 PF06459.7 EMR70702.1 - 7.4 6.3 6.6 12 5.7 1.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 adh_short PF00106.20 EMR70703.1 - 2.2e-19 70.0 0.4 2.7e-19 69.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR70703.1 - 2.7e-07 30.4 0.1 3.7e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR70703.1 - 1.7e-06 27.9 0.0 2.3e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MRP_L53 PF10780.4 EMR70704.1 - 1.4e-18 66.6 0.1 1.9e-18 66.1 0.1 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sld5 PF05916.6 EMR70705.1 - 1e-06 29.0 0.1 1.6e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein Abhydrolase_6 PF12697.2 EMR70706.1 - 7e-21 75.1 2.5 1.1e-20 74.5 1.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR70706.1 - 1.3e-09 37.9 0.9 3.1e-09 36.7 0.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EMR70706.1 - 7.5e-08 32.8 0.1 1.1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 EMR70706.1 - 0.00033 20.2 0.1 0.009 15.5 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMR70706.1 - 0.076 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase MgsA_C PF12002.3 EMR70707.1 - 8.3e-58 194.7 0.1 2e-57 193.5 0.0 1.6 2 0 0 2 2 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EMR70707.1 - 1.3e-13 51.2 0.1 3e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EMR70707.1 - 1.2e-09 37.5 0.0 2.8e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 EMR70707.1 - 2.3e-06 27.1 0.2 3.9e-05 23.1 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 EMR70707.1 - 8e-06 25.6 0.0 0.00031 20.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMR70707.1 - 4.2e-05 23.6 0.5 0.00025 21.2 0.4 2.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EMR70707.1 - 5.4e-05 22.4 0.1 0.094 11.8 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EMR70707.1 - 0.00011 21.9 0.0 0.00035 20.2 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EMR70707.1 - 0.00019 21.4 1.8 0.018 15.0 0.0 3.1 2 2 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 EMR70707.1 - 0.0017 17.1 0.0 0.0044 15.7 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 EMR70707.1 - 0.0019 17.1 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta2 PF13177.1 EMR70707.1 - 0.0041 16.8 0.0 0.28 10.8 0.0 2.5 2 1 1 3 3 2 1 DNA polymerase III, delta subunit AAA_3 PF07726.6 EMR70707.1 - 0.0041 16.7 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EMR70707.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.10 EMR70707.1 - 0.026 14.3 0.3 2.5 7.9 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit CPT PF07931.7 EMR70707.1 - 0.033 13.8 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.1 EMR70707.1 - 0.037 14.0 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain SKI PF01202.17 EMR70707.1 - 0.089 12.6 0.1 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_10 PF12846.2 EMR70707.1 - 0.12 11.8 1.2 13 5.0 0.2 2.7 1 1 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EMR70707.1 - 0.12 13.2 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EMR70707.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EMR70707.1 - 0.15 12.4 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EMR70707.1 - 0.16 12.3 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Bromodomain PF00439.20 EMR70708.1 - 3.8e-31 106.8 0.0 1e-16 60.6 0.0 2.5 2 0 0 2 2 2 2 Bromodomain p450 PF00067.17 EMR70709.1 - 1.6e-54 185.2 0.0 2.3e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EMR70710.1 - 7.7e-23 80.4 3.6 8.1e-23 80.3 0.9 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR70710.1 - 3.2e-20 71.9 3.0 3.2e-20 71.9 2.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 EMR70710.1 - 5.5e-05 23.7 0.2 0.0001 22.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Nop PF01798.13 EMR70711.1 - 3.5e-53 178.9 1.8 3.6e-52 175.6 1.2 2.4 1 1 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EMR70711.1 - 7.6e-27 92.8 1.5 1.1e-26 92.3 0.2 1.9 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EMR70711.1 - 3.9e-17 62.1 0.4 3.9e-17 62.1 0.3 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Gmx_para_CXXCG PF09535.5 EMR70711.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) PRiA4_ORF3 PF07929.6 EMR70712.1 - 2.6e-25 88.8 0.6 1.1e-23 83.5 0.4 2.2 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.13 EMR70712.1 - 2.1e-10 40.2 11.4 5e-10 39.0 7.9 1.7 1 0 0 1 1 1 1 MYND finger Utp12 PF04003.7 EMR70713.1 - 2.7e-22 78.7 0.1 3.7e-22 78.2 0.1 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family BUD22 PF09073.5 EMR70713.1 - 4.6 6.2 31.2 0.3 10.1 11.9 2.1 2 0 0 2 2 2 0 BUD22 vATP-synt_AC39 PF01992.11 EMR70714.1 - 8.4e-118 393.3 0.0 9.5e-118 393.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.17 EMR70715.1 - 8e-13 47.9 0.6 1.7e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 Suf PF05843.9 EMR70715.1 - 0.89 9.2 4.4 0.19 11.4 0.4 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ank_2 PF12796.2 EMR70716.1 - 1.7e-11 44.3 0.1 1.1e-05 25.6 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMR70716.1 - 6e-07 29.1 0.1 0.33 11.3 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.25 EMR70716.1 - 1.3e-06 27.8 0.1 0.1 12.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMR70716.1 - 0.024 14.9 0.2 0.96 9.7 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ribosomal_S2 PF00318.15 EMR70717.1 - 1.7e-42 145.0 0.0 1.1e-21 77.0 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 p450 PF00067.17 EMR70718.1 - 3.5e-27 95.0 0.0 5e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RasGEF PF00617.14 EMR70719.1 - 1.1e-48 165.4 0.0 1.6e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain Glyco_hydro_3 PF00933.16 EMR70721.1 - 3.8e-52 177.1 0.5 6.3e-52 176.4 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR70721.1 - 2.2e-47 161.4 0.1 4.4e-47 160.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR70721.1 - 2.7e-29 100.8 0.2 5.6e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Rpp20 PF12328.3 EMR70723.1 - 2.9e-26 91.8 0.6 3.8e-26 91.4 0.4 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EMR70723.1 - 4.5e-15 55.0 0.2 7.7e-15 54.2 0.1 1.4 1 0 0 1 1 1 1 Alba Cutinase PF01083.17 EMR70724.1 - 1.8e-23 83.2 0.0 2.7e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.2 EMR70724.1 - 4.2e-05 23.5 0.4 6.3e-05 22.9 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR70724.1 - 0.002 17.6 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EMR70724.1 - 0.081 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PE-PPE PF08237.6 EMR70724.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain DUF676 PF05057.9 EMR70724.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DAO PF01266.19 EMR70725.1 - 2.4e-41 141.8 1.5 3.9e-41 141.1 1.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMR70725.1 - 1.8e-06 27.7 0.6 0.0037 17.0 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMR70725.1 - 1.9e-05 24.6 0.1 0.0027 17.6 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR70725.1 - 0.00019 20.4 0.2 0.0072 15.2 0.0 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EMR70725.1 - 0.00085 19.4 0.0 0.26 11.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR70725.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMR70725.1 - 0.047 12.6 0.2 0.55 9.0 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EMR70725.1 - 0.091 13.1 0.2 0.46 10.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMR70725.1 - 0.26 9.8 1.5 9.7 4.6 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Rogdi_lz PF10259.4 EMR70726.1 - 1.8e-52 178.1 0.0 6.1e-52 176.3 0.0 1.7 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein Suf PF05843.9 EMR70726.1 - 0.2 11.3 0.9 0.33 10.6 0.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 EMR70726.1 - 0.73 9.1 12.0 1.3 8.3 8.3 1.4 1 0 0 1 1 1 0 Vta1 like MFS_1 PF07690.11 EMR70727.1 - 3.6e-11 42.3 31.5 3.3e-10 39.2 21.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EMR70727.1 - 0.00031 19.2 10.5 0.00031 19.2 7.3 2.0 2 0 0 2 2 2 2 MFS/sugar transport protein PCI PF01399.22 EMR70728.1 - 3e-20 72.4 0.0 9e-20 70.9 0.0 1.8 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 EMR70728.1 - 0.015 14.6 0.7 0.19 11.0 0.1 2.5 3 0 0 3 3 3 0 Putative aspartate racemase EST1_DNA_bind PF10373.4 EMR70728.1 - 0.057 12.6 0.3 0.64 9.1 0.0 2.3 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain PCI_Csn8 PF10075.4 EMR70728.1 - 0.093 12.4 0.7 0.39 10.4 0.0 2.3 3 1 1 4 4 4 0 COP9 signalosome, subunit CSN8 NIPSNAP PF07978.8 EMR70729.1 - 4.7e-39 132.4 5.8 8e-29 99.6 0.1 2.7 3 0 0 3 3 3 2 NIPSNAP ASD2 PF08687.6 EMR70729.1 - 0.017 14.4 0.2 0.03 13.6 0.1 1.4 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 NmrA PF05368.8 EMR70730.1 - 4.8e-16 58.7 0.0 6.9e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR70730.1 - 6e-14 52.4 0.0 1.9e-13 50.8 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EMR70730.1 - 3.4e-06 26.6 0.1 0.00016 21.2 0.0 2.9 3 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 EMR70730.1 - 0.059 13.1 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.12 EMR70730.1 - 0.11 11.3 0.0 3.1 6.6 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 EMR70730.1 - 0.18 10.4 0.0 0.29 9.8 0.0 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FSH1 PF03959.8 EMR70731.1 - 2.6e-55 187.1 0.0 3.5e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EMR70731.1 - 0.00031 20.7 2.9 0.0012 18.7 2.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR70731.1 - 0.00038 20.2 0.2 0.00068 19.4 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.4 EMR70731.1 - 0.01 14.7 0.2 0.018 13.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF2631 PF10939.3 EMR70731.1 - 0.039 13.7 0.6 0.039 13.7 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) Abhydrolase_2 PF02230.11 EMR70731.1 - 0.11 11.9 0.2 3.2 7.1 0.1 2.9 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase p450 PF00067.17 EMR70732.1 - 2.6e-51 174.6 0.0 4.3e-51 173.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 F-box PF00646.28 EMR70733.1 - 0.0033 17.0 0.5 0.008 15.8 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMR70733.1 - 0.0063 16.2 0.6 0.021 14.5 0.2 2.0 2 0 0 2 2 2 1 F-box-like peroxidase PF00141.18 EMR70735.1 - 8.6e-84 280.6 0.0 8.5e-46 156.2 0.0 2.3 2 0 0 2 2 2 2 Peroxidase GFA PF04828.9 EMR70737.1 - 3.6e-16 58.8 0.2 5.3e-16 58.3 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.11 EMR70738.1 - 1.1e-33 116.3 18.7 1.1e-33 116.3 13.0 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.14 EMR70738.1 - 0.00087 17.9 6.8 0.0016 17.0 4.7 1.5 1 1 0 1 1 1 1 LacY proton/sugar symporter Acetyltransf_1 PF00583.19 EMR70739.1 - 1.5e-11 44.1 0.0 2.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMR70739.1 - 3.6e-10 40.0 0.1 4.4e-10 39.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR70739.1 - 2.7e-09 37.0 0.0 4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMR70739.1 - 2.4e-06 27.5 0.0 3.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMR70739.1 - 2.9e-05 23.9 0.0 4.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR70739.1 - 0.00063 19.6 0.1 0.0021 17.9 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMR70739.1 - 0.0027 17.8 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Herpes_U34 PF04541.8 EMR70739.1 - 0.033 13.0 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus virion protein U34 Peptidase_M19 PF01244.16 EMR70740.1 - 4.8e-72 242.5 0.0 5.9e-72 242.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Sugar_tr PF00083.19 EMR70741.1 - 2.6e-82 276.8 17.6 3.1e-82 276.5 12.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR70741.1 - 3.5e-27 95.0 18.0 5.4e-27 94.4 12.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_16 PF00722.16 EMR70742.1 - 2.6e-10 39.8 0.3 3.9e-10 39.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Tannase PF07519.6 EMR70743.1 - 2.8e-83 280.2 0.1 7.7e-81 272.1 0.0 2.0 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 EMR70743.1 - 1.3e-07 31.0 0.3 0.0022 17.2 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EMR70743.1 - 2.7e-06 27.4 0.0 4.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR70743.1 - 0.0036 17.0 0.1 0.053 13.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR70743.1 - 0.0052 16.3 0.0 0.011 15.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 EMR70743.1 - 0.047 13.1 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase UDP-g_GGTase PF06427.6 EMR70743.1 - 0.071 12.4 0.1 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose:Glycoprotein Glucosyltransferase DLH PF01738.13 EMR70744.1 - 3.3e-28 98.4 0.1 3.8e-28 98.2 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMR70744.1 - 6.8e-06 25.8 0.0 1.3e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR70744.1 - 0.0058 16.5 0.0 0.038 13.8 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Sulfatase PF00884.18 EMR70744.1 - 0.032 13.4 0.0 0.041 13.0 0.0 1.3 1 1 0 1 1 1 0 Sulfatase BAAT_C PF08840.6 EMR70744.1 - 0.038 13.6 0.1 1.9 8.1 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EMR70744.1 - 0.041 13.1 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PAP2 PF01569.16 EMR70745.1 - 9.9e-24 83.4 0.5 9.9e-24 83.4 0.3 2.1 2 0 0 2 2 2 1 PAP2 superfamily YhhN PF07947.9 EMR70745.1 - 0.021 14.2 0.7 0.46 9.8 0.0 2.2 2 0 0 2 2 2 0 YhhN-like protein FF PF01846.14 EMR70747.1 - 9.8e-10 38.2 4.2 2.5e-08 33.7 0.1 3.1 3 0 0 3 3 3 2 FF domain WW PF00397.21 EMR70747.1 - 5.1e-09 35.8 1.5 5.1e-09 35.8 1.1 3.1 3 0 0 3 3 3 1 WW domain PNRC PF15365.1 EMR70747.1 - 3.1 7.8 13.1 16 5.6 0.3 2.9 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator Amidoligase_2 PF12224.3 EMR70748.1 - 8e-17 61.6 0.0 1.3e-12 47.8 0.0 2.2 2 0 0 2 2 2 2 Putative amidoligase enzyme Dynamin_N PF00350.18 EMR70749.1 - 7.6e-23 81.1 0.0 1.8e-21 76.6 0.0 2.5 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 EMR70749.1 - 0.0099 15.7 0.8 0.059 13.2 0.0 2.6 3 0 0 3 3 3 1 Dynamin GTPase effector domain Dynamin_M PF01031.15 EMR70749.1 - 0.035 12.8 0.4 0.12 11.0 0.3 1.9 1 1 1 2 2 2 0 Dynamin central region Flagellin_C PF00700.16 EMR70749.1 - 0.056 13.6 0.3 0.16 12.1 0.2 1.8 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region ABC_tran PF00005.22 EMR70749.1 - 0.068 13.4 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Miro PF08477.8 EMR70749.1 - 0.073 13.5 0.1 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein SQS_PSY PF00494.14 EMR70750.1 - 0.08 12.2 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Squalene/phytoene synthase Excalibur PF05901.6 EMR70751.1 - 0.64 10.4 2.2 24 5.3 0.0 3.1 3 0 0 3 3 3 0 Excalibur calcium-binding domain Abhydrolase_6 PF12697.2 EMR70752.1 - 2.3e-24 86.5 0.0 4.3e-24 85.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR70752.1 - 8.5e-13 48.3 0.1 3.3e-11 43.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR70752.1 - 9.9e-10 38.3 0.0 2.4e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EMR70752.1 - 0.057 12.6 0.0 0.27 10.4 0.0 2.0 2 1 0 2 2 2 0 Dienelactone hydrolase family FTA2 PF13095.1 EMR70753.1 - 2.3e-25 89.4 0.0 3e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Amidohydro_4 PF13147.1 EMR70754.1 - 2.2e-22 80.3 5.4 8.4e-21 75.2 3.7 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EMR70754.1 - 1.4e-16 61.1 0.0 2e-10 40.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EMR70754.1 - 1.3e-11 44.4 3.5 2.9e-09 36.6 0.2 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EMR70754.1 - 1.1e-06 28.3 3.6 2.3e-06 27.3 2.5 1.5 1 0 0 1 1 1 1 Amidohydrolase CH PF00307.26 EMR70755.1 - 2.7e-38 130.3 0.2 1.2e-18 67.1 0.0 2.9 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EMR70755.1 - 1.5e-26 92.1 0.0 4.6e-26 90.5 0.0 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EMR70755.1 - 9.9e-13 47.5 0.4 1.5e-06 27.7 0.0 3.4 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 EMR70755.1 - 0.0013 18.4 0.1 0.014 15.2 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EMR70755.1 - 0.017 14.7 0.6 0.25 10.9 0.1 3.0 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.1 EMR70755.1 - 0.058 13.5 1.4 0.25 11.5 0.3 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 EMR70755.1 - 0.094 12.0 0.1 1.3 8.5 0.0 2.7 2 0 0 2 2 2 0 EF hand SF-assemblin PF06705.6 EMR70755.1 - 1.5 7.8 4.7 14 4.7 0.3 2.4 2 0 0 2 2 2 0 SF-assemblin/beta giardin GARS_A PF01071.14 EMR70756.1 - 5.1e-84 280.6 0.0 8e-84 280.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EMR70756.1 - 2.7e-34 117.6 0.0 1e-33 115.7 0.0 2.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EMR70756.1 - 7e-28 97.5 0.0 2.2e-27 95.9 0.0 1.9 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EMR70756.1 - 3.2e-23 81.7 0.6 8.1e-23 80.4 0.2 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EMR70756.1 - 4.7e-15 55.6 3.7 4.7e-15 55.6 2.6 2.6 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EMR70756.1 - 1.4e-10 41.1 0.0 3.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMR70756.1 - 4.6e-10 38.7 0.0 1e-09 37.5 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EMR70756.1 - 1.7e-05 24.2 0.0 3.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EMR70756.1 - 0.00026 20.3 0.0 0.00058 19.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EMR70756.1 - 0.00076 19.3 0.1 0.0034 17.2 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 EMR70756.1 - 0.032 13.7 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.5 EMR70756.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Lipase_3 PF01764.20 EMR70757.1 - 0.0002 20.9 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EMR70757.1 - 0.069 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR70757.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family HLH PF00010.21 EMR70758.1 - 2.3e-12 46.4 0.2 6.9e-12 44.8 0.2 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TSC22 PF01166.13 EMR70758.1 - 0.54 10.2 3.5 0.31 11.0 0.4 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF2431 PF10354.4 EMR70759.1 - 2.1e-56 190.4 0.0 2.6e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltransf_26 PF13659.1 EMR70759.1 - 0.0059 16.6 0.0 0.0088 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Toxin_66 PF15544.1 EMR70760.1 - 0.038 13.2 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative toxin 66 DUF4570 PF15134.1 EMR70760.1 - 0.18 11.6 1.4 0.37 10.6 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) NDUF_B12 PF08122.7 EMR70761.1 - 6.5e-16 57.8 0.5 9.4e-16 57.2 0.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family VPS9 PF02204.13 EMR70762.1 - 6.4e-25 87.1 0.0 1e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CLTH PF10607.4 EMR70763.1 - 2.4e-31 108.4 0.0 3.8e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Zip PF02535.17 EMR70763.1 - 0.0015 17.5 6.8 0.0021 17.1 4.7 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter SR-25 PF10500.4 EMR70763.1 - 0.076 12.4 11.8 0.71 9.2 0.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Hid1 PF12722.2 EMR70763.1 - 0.12 10.0 6.6 0.16 9.5 4.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 EMR70763.1 - 1.2 7.4 7.1 1.8 6.8 4.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.4 EMR70763.1 - 2.2 6.4 19.4 3 5.9 13.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AUX_IAA PF02309.11 EMR70763.1 - 3.4 7.3 7.4 0.46 10.2 1.9 1.8 2 0 0 2 2 2 0 AUX/IAA family Dicty_REP PF05086.7 EMR70763.1 - 5.7 4.5 8.2 8.1 4.0 5.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CytochromB561_N PF09786.4 EMR70764.1 - 0.0032 16.0 3.5 0.0032 16.0 2.5 1.6 2 0 0 2 2 2 1 Cytochrome B561, N terminal Chorion_2 PF03964.10 EMR70764.1 - 0.16 12.5 5.1 0.95 10.0 3.5 2.4 1 1 0 1 1 1 0 Chorion family 2 CAF1 PF04857.15 EMR70765.1 - 6.1e-36 124.0 0.1 9.3e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease ThiF PF00899.16 EMR70766.1 - 2.4e-16 59.7 0.0 3.8e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family eIF-5_eIF-2B PF01873.12 EMR70767.1 - 3.5e-40 136.5 0.0 6e-40 135.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EMR70767.1 - 6.9e-26 90.0 1.2 2.6e-25 88.1 0.8 2.1 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NOA36 PF06524.7 EMR70767.1 - 0.093 11.9 7.4 0.17 11.0 5.1 1.4 1 0 0 1 1 1 0 NOA36 protein INTS5_N PF14837.1 EMR70768.1 - 0.055 12.8 0.6 0.095 12.1 0.4 1.3 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus eIF-6 PF01912.13 EMR70769.1 - 6.3e-83 276.7 1.2 8.4e-83 276.3 0.8 1.1 1 0 0 1 1 1 1 eIF-6 family PUF PF00806.14 EMR70771.1 - 6.2e-55 179.7 11.1 1.8e-08 33.3 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 EMR70771.1 - 0.043 14.0 0.8 7.8 6.8 0.2 3.0 2 2 0 2 2 2 0 Protein of unknown function DUF260 Tenui_NCP PF04876.7 EMR70771.1 - 0.065 12.7 1.0 2.7 7.5 0.1 2.4 1 1 0 2 2 2 0 Tenuivirus major non-capsid protein ArfGap PF01412.13 EMR70771.1 - 0.083 12.6 0.5 5.1 6.9 0.1 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf MgtE_N PF03448.12 EMR70771.1 - 0.086 13.1 0.5 1.4 9.2 0.2 2.6 2 1 0 2 2 2 0 MgtE intracellular N domain CoaE PF01121.15 EMR70772.1 - 7.7e-42 142.7 0.0 2.6e-41 141.0 0.0 1.7 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.1 EMR70772.1 - 0.0027 17.5 0.0 0.018 14.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMR70772.1 - 0.022 15.5 0.4 0.062 14.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EMR70772.1 - 0.039 14.2 0.6 0.51 10.6 0.4 2.4 1 1 0 1 1 1 0 AAA domain SKI PF01202.17 EMR70772.1 - 0.055 13.3 0.0 8.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase THUMP PF02926.12 EMR70774.1 - 1.3e-09 38.1 0.6 1.4e-08 34.7 0.4 2.0 1 1 0 1 1 1 1 THUMP domain HSF_DNA-bind PF00447.12 EMR70776.1 - 5.5e-34 116.4 0.2 1.3e-33 115.2 0.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 EMR70776.1 - 2e-21 76.0 0.1 3.6e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain DUF972 PF06156.8 EMR70776.1 - 0.018 15.4 2.0 0.037 14.3 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Mod_r PF07200.8 EMR70776.1 - 0.018 14.9 2.3 0.031 14.2 1.6 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein CENP-Q PF13094.1 EMR70776.1 - 0.054 13.5 4.7 0.086 12.8 3.2 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_TATA_bd PF12325.3 EMR70776.1 - 0.24 11.1 5.3 0.47 10.2 3.7 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EMR70776.1 - 0.65 9.5 6.9 1 8.9 4.8 1.2 1 0 0 1 1 1 0 IncA protein CENP-H PF05837.7 EMR70776.1 - 2.2 8.5 5.9 3.9 7.6 4.1 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Dynamin_N PF00350.18 EMR70777.1 - 3.9e-43 147.1 0.0 6.8e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin family PQ-loop PF04193.9 EMR70777.1 - 1.8e-32 110.6 11.0 7.8e-16 57.3 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat Dynamin_M PF01031.15 EMR70777.1 - 2.5e-11 42.9 0.2 1.8e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EMR70777.1 - 0.0042 17.0 0.0 0.015 15.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EMR70777.1 - 0.0045 17.4 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein DUF3357 PF11837.3 EMR70777.1 - 0.087 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) AAA_10 PF12846.2 EMR70777.1 - 0.088 12.2 0.3 0.31 10.4 0.2 1.9 1 1 0 1 1 1 0 AAA-like domain AAA_21 PF13304.1 EMR70777.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EMR70777.1 - 0.19 11.6 2.1 0.55 10.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.22 EMR70778.1 - 3.3e-47 160.2 0.0 5.3e-22 78.6 0.0 3.2 3 1 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EMR70778.1 - 1.3e-18 66.5 6.9 1.3e-18 66.5 4.8 4.1 3 1 1 4 4 2 1 ABC transporter AAA_21 PF13304.1 EMR70778.1 - 2.9e-15 57.0 6.8 0.00043 20.3 0.0 4.7 3 2 1 4 4 4 3 AAA domain SMC_N PF02463.14 EMR70778.1 - 7.3e-11 41.7 0.6 0.007 15.6 0.0 4.5 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EMR70778.1 - 1.2e-09 38.9 0.4 0.0022 18.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EMR70778.1 - 7.6e-07 28.5 0.1 0.017 14.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EMR70778.1 - 1e-06 28.0 0.1 0.016 14.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EMR70778.1 - 2.6e-06 27.3 0.0 0.016 15.1 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EMR70778.1 - 3.7e-06 27.4 0.1 0.025 15.0 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 EMR70778.1 - 4.8e-06 26.9 1.8 0.096 12.9 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EMR70778.1 - 6.3e-06 26.3 1.7 0.0057 16.6 0.2 2.9 2 0 0 2 2 2 2 AAA ATPase domain MobB PF03205.9 EMR70778.1 - 1.6e-05 24.6 0.5 0.21 11.3 0.2 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EMR70778.1 - 2.3e-05 24.5 0.2 0.34 11.0 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EMR70778.1 - 7.3e-05 22.6 0.0 0.33 10.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EMR70778.1 - 9.7e-05 22.5 0.0 0.34 11.0 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EMR70778.1 - 0.00019 21.8 0.2 0.0056 17.0 0.0 4.6 4 1 1 5 5 4 2 AAA domain NACHT PF05729.7 EMR70778.1 - 0.0002 21.0 0.1 0.29 10.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain ArgK PF03308.11 EMR70778.1 - 0.00032 19.5 0.3 0.56 8.9 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_15 PF13175.1 EMR70778.1 - 0.00049 19.2 13.4 0.18 10.8 0.1 5.0 4 2 1 5 5 5 2 AAA ATPase domain AAA_25 PF13481.1 EMR70778.1 - 0.00061 19.2 0.0 0.69 9.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EMR70778.1 - 0.00063 19.6 0.0 0.81 9.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EMR70778.1 - 0.00069 19.6 4.5 0.072 13.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.10 EMR70778.1 - 0.0018 17.9 0.1 0.32 10.7 0.1 2.7 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.17 EMR70778.1 - 0.0023 18.0 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase cobW PF02492.14 EMR70778.1 - 0.0042 16.5 0.5 1.2 8.5 0.4 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 EMR70778.1 - 0.0046 16.8 0.4 2.3 8.1 0.1 3.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 EMR70778.1 - 0.005 16.3 0.2 1.7 8.0 0.0 2.7 2 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EMR70778.1 - 0.005 16.3 0.0 0.87 8.9 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain GTP_EFTU PF00009.22 EMR70778.1 - 0.01 15.2 1.5 5.2 6.4 0.0 3.5 4 0 0 4 4 4 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.17 EMR70778.1 - 0.018 13.9 0.0 5 5.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain T2SE PF00437.15 EMR70778.1 - 0.019 13.8 0.0 0.52 9.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.9 EMR70778.1 - 0.021 14.5 0.3 5.8 6.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EMR70778.1 - 0.029 13.7 2.1 1.5 8.1 0.0 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 EMR70778.1 - 0.045 13.2 0.4 2 7.8 0.0 2.8 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 EMR70778.1 - 0.054 13.2 0.4 2.8 7.7 0.1 3.2 3 0 0 3 3 3 0 Part of AAA domain Dynamin_N PF00350.18 EMR70778.1 - 0.057 13.2 9.0 0.98 9.2 0.6 4.3 3 1 0 3 3 3 0 Dynamin family PduV-EutP PF10662.4 EMR70778.1 - 0.083 12.3 0.1 16 4.9 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EMR70778.1 - 0.39 10.2 1.8 24 4.3 0.1 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 EMR70778.1 - 4.4 7.0 12.9 0.29 10.9 0.1 3.8 5 0 0 5 5 5 0 Domain of unknown function DUF87 Flavoprotein PF02441.14 EMR70780.1 - 7.7e-16 57.9 0.2 1.6e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 Flavoprotein WD40 PF00400.27 EMR70781.1 - 3.2e-50 166.2 22.5 1.6e-11 43.6 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EMR70781.1 - 1.6e-09 37.7 14.8 0.0025 17.5 0.1 4.2 1 1 3 5 5 5 3 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 EMR70781.1 - 0.11 12.3 0.0 24 4.8 0.0 3.2 4 0 0 4 4 4 0 YmzC-like protein IKI3 PF04762.7 EMR70781.1 - 0.38 8.5 4.2 9.7 3.8 0.9 2.7 1 1 0 3 3 3 0 IKI3 family bZIP_1 PF00170.16 EMR70782.1 - 5.9e-12 45.3 3.6 1.1e-11 44.4 2.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMR70782.1 - 1.3e-06 28.1 6.9 2.4e-06 27.2 4.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper TTKRSYEDQ PF10212.4 EMR70782.1 - 0.0048 15.8 0.0 0.0065 15.4 0.0 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein GSDH PF07995.6 EMR70784.1 - 1.1e-09 37.8 0.0 5.3e-09 35.5 0.0 1.9 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 EMR70784.1 - 0.0015 18.4 0.0 4.4 7.4 0.0 3.9 4 0 0 4 4 4 2 NHL repeat SGL PF08450.7 EMR70784.1 - 0.0048 16.2 0.1 0.069 12.5 0.0 2.4 2 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region SBBP PF06739.6 EMR70784.1 - 0.0074 16.0 0.0 4.3 7.1 0.0 2.8 3 0 0 3 3 3 2 Beta-propeller repeat HCBP_related PF06594.6 EMR70784.1 - 0.034 13.7 0.1 5.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain Methyltransf_1N PF02870.10 EMR70784.1 - 0.062 13.8 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Membrane_bind PF14564.1 EMR70787.1 - 4.3e-24 84.8 0.1 8.7e-23 80.6 0.0 2.4 1 1 0 1 1 1 1 Membrane binding Crystall_3 PF08964.5 EMR70787.1 - 1e-16 60.4 0.0 2.1e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Beta/Gamma crystallin Syncollin PF15138.1 EMR70787.1 - 0.0042 16.9 0.0 0.059 13.2 0.0 2.1 2 0 0 2 2 2 1 Syncollin adh_short PF00106.20 EMR70789.1 - 0.0005 20.0 0.0 0.00056 19.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR70789.1 - 0.036 13.7 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 KR domain FTA2 PF13095.1 EMR70790.1 - 5.9e-23 81.5 0.0 8.2e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 SYF2 PF08231.7 EMR70791.1 - 1.8e-48 164.5 7.9 1.8e-48 164.5 5.5 2.1 2 1 0 2 2 2 1 SYF2 splicing factor ARD PF03079.9 EMR70791.1 - 5.7 6.8 7.8 0.66 9.9 0.1 2.7 2 1 1 3 3 3 0 ARD/ARD' family 4HBT_3 PF13622.1 EMR70792.1 - 0.0012 18.6 1.9 0.0012 18.6 1.3 1.9 1 1 1 2 2 2 2 Thioesterase-like superfamily GST_C PF00043.20 EMR70793.1 - 1.4e-12 47.3 0.0 2.2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMR70793.1 - 7.8e-12 45.1 0.0 2.8e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EMR70793.1 - 1.3e-09 38.1 0.0 2.8e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMR70793.1 - 3.8e-09 36.4 0.0 9e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR70793.1 - 5.5e-09 35.7 0.2 9.9e-09 34.9 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR70793.1 - 8.3e-08 32.6 0.1 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3987 PF13148.1 EMR70793.1 - 0.054 12.0 0.1 0.076 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4301 PF14134.1 EMR70793.1 - 0.16 10.5 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) EST1_DNA_bind PF10373.4 EMR70794.1 - 0.075 12.2 0.0 0.083 12.0 0.0 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Sugar_tr PF00083.19 EMR70797.1 - 2.3e-48 164.9 1.5 2.7e-48 164.6 1.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR70797.1 - 2e-22 79.4 6.9 2.5e-22 79.0 4.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 EMR70797.1 - 0.0012 17.0 0.1 0.0017 16.5 0.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.1 EMR70797.1 - 0.0063 14.9 1.9 0.0089 14.4 1.3 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.8 EMR70797.1 - 0.0096 14.1 0.4 0.012 13.8 0.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EMR70797.1 - 0.029 14.1 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 MFS_1 like family FAD-oxidase_C PF02913.14 EMR70798.1 - 5.6e-64 215.8 0.3 2.6e-63 213.6 0.3 1.9 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMR70798.1 - 3.9e-21 74.9 0.0 1.2e-20 73.3 0.0 1.9 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 EMR70798.1 - 0.066 11.6 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Peptidase_S9 PF00326.16 EMR70799.1 - 1.6e-45 154.9 0.0 1.9e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMR70799.1 - 3.3e-08 33.3 0.0 4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR70799.1 - 2e-05 24.5 0.2 0.00018 21.4 0.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.3 EMR70799.1 - 0.011 14.8 0.0 0.3 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Trypsin PF00089.21 EMR70800.1 - 8e-10 38.6 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EMR70800.1 - 8.1e-06 25.8 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Aspzincin_M35 PF14521.1 EMR70801.1 - 2.4e-21 76.7 0.3 3.5e-21 76.2 0.2 1.2 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EMR70801.1 - 0.014 14.8 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Putative peptidase family Cut8_C PF08559.5 EMR70801.1 - 0.085 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Cut8 six-helix bundle Dioxygenase_C PF00775.16 EMR70803.1 - 3e-10 39.6 0.7 6.9e-10 38.4 0.5 1.6 1 1 0 1 1 1 1 Dioxygenase LVIVD PF08309.6 EMR70804.1 - 0.01 14.7 0.1 13 4.8 0.0 3.6 3 0 0 3 3 3 0 LVIVD repeat Aa_trans PF01490.13 EMR70805.1 - 8.1e-33 113.4 31.0 9.4e-33 113.2 21.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EMR70805.1 - 1.2e-06 27.3 39.6 0.00019 20.1 27.4 2.6 1 1 0 1 1 1 1 Amino acid permease DUF2583 PF10762.4 EMR70805.1 - 0.025 14.7 1.0 0.13 12.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) DUF912 PF06024.7 EMR70805.1 - 0.11 12.5 0.2 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3733 PF12534.3 EMR70805.1 - 0.38 10.0 3.7 0.25 10.6 0.5 2.2 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 DUF872 PF05915.7 EMR70805.1 - 4.6 7.1 7.5 22 4.9 0.0 3.4 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) CorA PF01544.13 EMR70806.1 - 2.4e-21 76.0 11.5 3.1e-14 52.6 2.2 3.1 2 1 1 3 3 3 3 CorA-like Mg2+ transporter protein AARP2CN PF08142.7 EMR70806.1 - 0.048 13.1 0.2 0.21 11.1 0.1 2.0 1 1 0 1 1 1 0 AARP2CN (NUC121) domain DUF3722 PF12519.3 EMR70807.1 - 1.3e-83 280.2 0.0 1.6e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 EMR70807.1 - 0.011 15.0 0.0 0.84 8.8 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic porin FAD_binding_4 PF01565.18 EMR70808.1 - 3.7e-05 23.2 0.0 6.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EMR70808.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin Polysacc_deac_1 PF01522.16 EMR70810.1 - 8.4e-22 77.1 0.0 1.6e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2194 PF09960.4 EMR70810.1 - 0.012 13.6 0.0 0.016 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) DUF2334 PF10096.4 EMR70810.1 - 0.052 12.9 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Zip PF02535.17 EMR70811.1 - 1e-55 188.9 9.4 1.8e-55 188.2 6.5 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Rad9 PF04139.8 EMR70812.1 - 2e-44 151.5 0.8 2.4e-34 118.6 0.0 2.1 1 1 1 2 2 2 2 Rad9 Amino_oxidase PF01593.19 EMR70814.1 - 2e-62 211.7 1.0 2.5e-61 208.1 0.7 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMR70814.1 - 2.5e-10 40.2 0.4 5.6e-10 39.1 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR70814.1 - 7.4e-05 22.9 0.0 0.00019 21.5 0.0 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR70814.1 - 0.0029 17.5 0.1 0.0047 16.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR70814.1 - 0.0043 15.9 0.0 0.0081 15.0 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Shikimate_DH PF01488.15 EMR70814.1 - 0.0047 17.0 0.0 0.0093 16.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EMR70814.1 - 0.0062 15.6 0.4 0.029 13.4 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EMR70814.1 - 0.032 13.1 0.2 0.089 11.6 0.1 1.8 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR70814.1 - 0.036 14.4 0.1 0.17 12.3 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EMR70814.1 - 0.038 13.8 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 ThiF family FAD_binding_2 PF00890.19 EMR70814.1 - 0.045 12.5 0.2 0.065 12.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EMR70814.1 - 0.056 13.2 0.2 0.47 10.2 0.0 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EMR70814.1 - 0.077 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EMR70814.1 - 0.11 10.8 0.1 0.19 10.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EMR70814.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family AA_permease PF00324.16 EMR70815.1 - 1.2e-135 452.5 39.2 1.4e-135 452.3 27.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR70815.1 - 4.3e-43 147.4 41.5 5.7e-43 147.0 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease Alk_phosphatase PF00245.15 EMR70816.1 - 6.8e-106 354.4 0.0 1e-105 353.8 0.0 1.3 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EMR70816.1 - 9.4e-06 25.1 0.1 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF2413 PF10310.4 EMR70817.1 - 1.9 7.2 5.9 0.32 9.7 1.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) PDH PF02153.12 EMR70818.1 - 1e-15 57.3 0.1 1.5e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase LRR_4 PF12799.2 EMR70819.1 - 0.00065 19.2 0.1 3.9 7.1 0.1 4.0 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) Ribosomal_S19e PF01090.14 EMR70820.1 - 9.2e-57 190.3 0.2 1.1e-56 190.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e GST_C_3 PF14497.1 EMR70822.1 - 1.8e-09 37.9 0.0 2.5e-09 37.4 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMR70822.1 - 3.5e-06 26.8 0.3 5.7e-05 23.0 0.0 2.1 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMR70822.1 - 0.014 15.3 0.0 0.078 12.8 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF2489 PF10675.4 EMR70822.1 - 0.14 11.8 0.1 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Lipase_GDSL PF00657.17 EMR70823.1 - 2.5e-16 60.2 0.1 3.3e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EMR70823.1 - 1.8e-15 57.5 0.4 2.5e-15 57.0 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EMR70823.1 - 0.0018 18.0 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.11 EMR70824.1 - 8.2e-20 70.8 48.5 2.4e-11 42.9 10.0 3.2 2 1 2 4 4 4 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR70824.1 - 7.7e-06 24.7 33.9 5.8e-05 21.8 4.9 2.9 2 1 2 4 4 4 2 Sugar (and other) transporter DUF1418 PF07214.7 EMR70824.1 - 0.28 10.8 6.5 0.086 12.4 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Pyr_redox_2 PF07992.9 EMR70825.1 - 5.7e-14 52.4 0.0 9.3e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR70825.1 - 7e-06 24.7 0.0 0.0026 16.3 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EMR70825.1 - 9.4e-05 22.5 0.1 0.1 12.6 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR70825.1 - 0.00042 19.2 0.0 0.00068 18.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EMR70825.1 - 0.0009 18.3 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EMR70825.1 - 0.0015 18.3 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.12 EMR70825.1 - 0.0024 17.0 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EMR70825.1 - 0.0055 16.6 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EMR70825.1 - 0.0062 15.6 0.2 0.029 13.4 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 EMR70825.1 - 0.012 14.5 0.3 0.043 12.7 0.1 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 EMR70825.1 - 0.014 14.2 0.0 0.16 10.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Methyltransf_11 PF08241.7 EMR70826.1 - 1.4e-11 44.7 0.0 1.8e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR70826.1 - 3.5e-09 36.1 0.0 3.6e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMR70826.1 - 2.9e-06 27.5 0.0 3.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR70826.1 - 0.0086 15.8 0.0 0.0095 15.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR70826.1 - 0.015 15.7 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EMR70826.1 - 0.027 14.0 0.0 0.027 14.0 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EMR70827.1 - 1.1e-05 24.3 12.3 2.5e-05 23.1 8.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EMR70827.1 - 0.0027 17.4 0.2 0.0072 16.1 0.1 1.7 1 0 0 1 1 1 1 MFS_1 like family Fungal_trans_2 PF11951.3 EMR70828.1 - 6.5e-25 87.5 0.1 7.6e-25 87.3 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EMR70829.1 - 4.4e-14 52.7 3.1 5.5e-14 52.4 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR70829.1 - 1.2e-09 38.1 1.8 1.5e-09 37.7 1.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR70829.1 - 3.3e-09 36.8 0.3 4.3e-09 36.4 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EMR70829.1 - 0.4 10.4 6.9 0.096 12.4 2.3 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.17 EMR70830.1 - 3.4e-51 174.2 0.0 4.1e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_C_2 PF13410.1 EMR70831.1 - 3.8e-06 26.6 0.1 6.2e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR70831.1 - 0.00024 21.5 0.2 0.00054 20.3 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMR70831.1 - 0.016 15.1 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NOT2_3_5 PF04153.13 EMR70832.1 - 0.048 13.5 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family SPA PF08616.5 EMR70833.1 - 3.5e-38 129.7 0.0 5.5e-38 129.1 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.4 EMR70833.1 - 0.0033 16.7 0.0 0.0078 15.5 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 EMR70833.1 - 0.019 13.4 0.0 0.45 8.9 0.0 2.1 1 1 1 2 2 2 0 Transport protein Avl9 DUF2554 PF10829.3 EMR70833.1 - 0.057 13.5 0.1 2.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2554) MFS_1 PF07690.11 EMR70834.1 - 1.1e-24 86.8 25.5 1.1e-24 86.8 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.8 EMR70834.1 - 0.014 15.4 0.1 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF360 PF04020.8 EMR70834.1 - 3.3 8.1 9.9 0.057 13.7 1.1 2.4 3 0 0 3 3 3 0 Membrane protein of unknown function adh_short PF00106.20 EMR70835.1 - 3.6e-13 49.7 0.0 5.9e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR70835.1 - 7.5e-07 28.9 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR70835.1 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR70835.1 - 0.0037 16.7 0.2 0.014 14.8 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EMR70835.1 - 0.007 15.3 0.5 0.27 10.1 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EMR70835.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.17 EMR70836.1 - 3.7e-67 226.8 0.0 4.8e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PQ-loop PF04193.9 EMR70838.1 - 5.9e-39 131.4 14.4 4.9e-21 74.0 0.2 3.2 3 0 0 3 3 3 2 PQ loop repeat S1-P1_nuclease PF02265.11 EMR70840.1 - 1.7e-73 247.4 0.1 1.9e-73 247.2 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PSI_PSAK PF01241.13 EMR70840.1 - 0.06 13.3 0.7 0.12 12.3 0.5 1.4 1 0 0 1 1 1 0 Photosystem I psaG / psaK Glyco_hydro_18 PF00704.23 EMR70841.1 - 1.1e-40 140.1 0.1 1.8e-39 136.1 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EMR70841.1 - 3.4e-05 23.7 19.5 9.8e-05 22.2 13.5 1.8 1 1 0 1 1 1 1 Chitin recognition protein YjbE PF11106.3 EMR70841.1 - 1.3 9.0 6.4 0.15 12.0 0.4 2.3 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE adh_short PF00106.20 EMR70842.1 - 1.5e-24 86.8 0.8 1.9e-24 86.4 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR70842.1 - 1.6e-24 87.0 0.0 1.9e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR70842.1 - 5.3e-09 35.9 0.4 8.1e-09 35.3 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR70842.1 - 0.00012 21.6 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EMR70842.1 - 0.039 13.7 0.1 0.19 11.5 0.0 2.1 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EMR70842.1 - 0.04 13.0 0.0 0.15 11.1 0.0 1.7 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) polyprenyl_synt PF00348.12 EMR70842.1 - 0.054 12.3 0.1 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Polyprenyl synthetase HLH PF00010.21 EMR70843.1 - 5.6e-08 32.3 0.0 1.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Rab5-bind PF09311.6 EMR70843.1 - 0.0013 18.6 0.3 0.0021 17.9 0.2 1.3 1 0 0 1 1 1 1 Rabaptin-like protein HD_4 PF13328.1 EMR70843.1 - 0.034 13.8 0.1 0.044 13.5 0.1 1.1 1 0 0 1 1 1 0 HD domain Angiomotin_C PF12240.3 EMR70843.1 - 0.074 12.5 1.0 0.086 12.3 0.7 1.2 1 0 0 1 1 1 0 Angiomotin C terminal DUF4047 PF13256.1 EMR70843.1 - 0.083 12.8 0.2 0.76 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Myb_CC_LHEQLE PF14379.1 EMR70843.1 - 1.2 8.8 4.3 0.33 10.5 0.5 2.0 2 1 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif Maf PF02545.9 EMR70844.1 - 1.4e-37 128.6 0.1 1.4e-28 99.3 0.0 2.1 2 0 0 2 2 2 2 Maf-like protein CDC45 PF02724.9 EMR70844.1 - 0.014 13.4 3.5 0.019 13.0 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_12 PF08242.7 EMR70844.1 - 0.084 13.3 0.2 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain eIF-3c_N PF05470.7 EMR70844.1 - 0.33 8.9 3.5 0.43 8.6 2.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Presenilin PF01080.12 EMR70844.1 - 0.55 8.9 1.3 0.71 8.6 0.9 1.1 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.1 EMR70844.1 - 1.2 9.3 5.6 2 8.5 3.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal tRNA-synt_2b PF00587.20 EMR70845.1 - 9.3e-49 165.3 0.0 1.4e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EMR70845.1 - 1.6e-06 27.9 0.0 3.5e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Anticodon binding domain Utp11 PF03998.8 EMR70847.1 - 3.9e-52 177.5 19.5 5e-52 177.1 13.5 1.1 1 0 0 1 1 1 1 Utp11 protein CAP18_C PF12153.3 EMR70847.1 - 0.31 10.7 4.1 2.8 7.6 0.6 2.6 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) DUF45 PF01863.12 EMR70847.1 - 0.85 9.3 5.7 0.54 10.0 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 WD40 PF00400.27 EMR70849.1 - 6.9e-07 28.9 14.6 0.059 13.2 0.2 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EMR70849.1 - 0.43 10.2 2.1 1.9 8.1 0.1 2.7 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A AMP-binding PF00501.23 EMR70850.1 - 4.9e-82 275.5 0.0 5.9e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme p450 PF00067.17 EMR70851.1 - 7.4e-62 209.3 0.0 9.7e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ILVD_EDD PF00920.16 EMR70852.1 - 1.8e-62 211.4 0.1 2.1e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family RTP801_C PF07809.6 EMR70852.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 RTP801 C-terminal region Chitin_synth_1 PF01644.12 EMR70854.1 - 1e-83 279.0 0.1 1.6e-83 278.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EMR70854.1 - 2.9e-33 113.3 0.2 6.5e-33 112.2 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EMR70854.1 - 3.5e-22 78.5 11.9 9.6e-21 73.7 0.0 2.9 2 1 1 3 3 3 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EMR70854.1 - 1.5e-09 37.8 0.2 1.5e-09 37.8 0.2 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EMR70854.1 - 5.7e-07 29.5 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Vps39_1 PF10366.4 EMR70855.1 - 0.069 13.1 0.2 0.086 12.8 0.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 TPR_10 PF13374.1 EMR70855.1 - 0.24 11.4 2.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Fringe PF02434.11 EMR70856.1 - 7.9e-07 28.5 0.0 2e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 Fringe-like PAN_2 PF08276.6 EMR70856.1 - 0.008 15.9 0.8 0.017 14.9 0.6 1.5 1 0 0 1 1 1 1 PAN-like domain PAN_3 PF08277.7 EMR70856.1 - 0.01 15.4 0.7 0.02 14.5 0.5 1.4 1 0 0 1 1 1 0 PAN-like domain PAN_4 PF14295.1 EMR70856.1 - 0.011 15.3 2.0 0.025 14.2 1.4 1.5 1 0 0 1 1 1 0 PAN domain DUF604 PF04646.7 EMR70856.1 - 0.037 13.2 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 YfdX PF10938.3 EMR70857.1 - 0.028 14.0 4.7 0.15 11.7 0.9 2.3 2 0 0 2 2 2 0 YfdX protein Prefoldin PF02996.12 EMR70857.1 - 4.7 6.8 8.5 0.37 10.4 2.1 1.9 2 0 0 2 2 2 0 Prefoldin subunit DUF4398 PF14346.1 EMR70857.1 - 5.4 7.1 22.6 0.79 9.8 5.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4398) ABC_tran PF00005.22 EMR70858.1 - 7e-21 74.9 0.0 1.3e-08 35.1 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMR70858.1 - 2.5e-08 34.2 0.0 0.082 12.8 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EMR70858.1 - 4.6e-06 27.4 0.0 0.17 12.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 EMR70858.1 - 0.00011 22.0 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EMR70858.1 - 0.0021 18.4 0.3 0.027 14.8 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EMR70858.1 - 0.0041 16.6 0.0 0.12 11.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Miro PF08477.8 EMR70858.1 - 0.0089 16.5 0.0 1.6 9.2 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EMR70858.1 - 0.0098 16.0 0.0 2.1 8.5 0.0 3.2 4 0 0 4 4 4 1 AAA domain AAA PF00004.24 EMR70858.1 - 0.039 14.1 0.1 0.49 10.5 0.0 2.9 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EMR70858.1 - 0.04 13.7 0.0 6.6 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EMR70858.1 - 0.066 12.6 0.0 3.1 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EMR70858.1 - 0.1 12.0 0.0 9.6 5.6 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EMR70858.1 - 0.12 12.3 2.6 17 5.3 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.17 EMR70858.1 - 0.17 12.0 0.0 4.6 7.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.12 EMR70858.1 - 0.3 10.5 0.1 4.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_13 PF13166.1 EMR70858.1 - 0.41 9.0 0.1 0.58 8.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain Rad60-SLD_2 PF13881.1 EMR70859.1 - 3.6e-13 49.3 0.1 8.6e-13 48.1 0.0 1.6 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EMR70859.1 - 0.00024 21.2 0.0 0.00058 20.0 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EMR70859.1 - 0.00037 19.8 0.0 0.001 18.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family Omp28 PF11551.3 EMR70859.1 - 0.055 13.0 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein Omp28 Glyco_hydro_17 PF00332.13 EMR70860.1 - 0.00016 20.8 0.4 0.0003 19.9 0.3 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 SoxE PF06525.6 EMR70861.1 - 0.019 14.2 1.9 0.033 13.4 1.3 1.3 1 0 0 1 1 1 0 Sulfocyanin (SoxE) YtxH PF12732.2 EMR70861.1 - 0.099 13.0 0.0 0.099 13.0 0.0 2.0 2 0 0 2 2 2 0 YtxH-like protein DUF3976 PF13121.1 EMR70861.1 - 0.49 10.2 2.1 0.99 9.3 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) SET PF00856.23 EMR70862.1 - 2.3e-10 41.0 0.1 3.5e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 SET domain FAD_binding_3 PF01494.14 EMR70863.1 - 2.5e-15 56.4 1.2 2.5e-12 46.5 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EMR70863.1 - 6.9e-05 22.7 0.1 0.00028 20.8 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR70863.1 - 0.0009 18.2 0.7 0.0026 16.7 0.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMR70863.1 - 0.0049 16.6 0.3 0.014 15.1 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EMR70863.1 - 0.01 16.2 0.1 0.025 14.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR70863.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR70863.1 - 0.13 11.1 0.4 0.33 9.8 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein SE PF08491.5 EMR70863.1 - 0.14 10.9 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase UMP1 PF05348.6 EMR70864.1 - 5.1e-22 78.2 0.0 6e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 SKG6 PF08693.5 EMR70865.1 - 0.0066 15.7 4.6 0.013 14.7 3.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DIOX_N PF14226.1 EMR70866.1 - 9.2e-17 61.6 0.0 3.1e-16 59.9 0.0 1.9 2 1 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EMR70866.1 - 8.3e-12 45.2 0.0 1.4e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BAR PF03114.13 EMR70867.1 - 0.099 12.1 2.3 0.25 10.8 1.6 1.6 1 1 0 1 1 1 0 BAR domain Transferase PF02458.10 EMR70867.1 - 0.18 10.1 1.8 0.25 9.7 1.3 1.1 1 0 0 1 1 1 0 Transferase family DUF3754 PF12576.3 EMR70868.1 - 0.7 9.5 6.5 0.035 13.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) CDC14 PF08045.6 EMR70869.1 - 2.3e-89 298.9 0.0 2.7e-89 298.6 0.0 1.1 1 0 0 1 1 1 1 Cell division control protein 14, SIN component PNGaseA PF12222.3 EMR70870.1 - 1.4e-49 169.1 0.4 5.4e-43 147.4 0.1 2.2 1 1 1 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A polyprenyl_synt PF00348.12 EMR70871.1 - 2.9e-58 196.7 0.0 3.6e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase mRNA_cap_enzyme PF01331.14 EMR70872.1 - 1.8e-53 181.0 0.1 2.4e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EMR70872.1 - 3.3e-18 65.9 0.0 1.1e-17 64.2 0.0 1.9 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EMR70872.1 - 2.3e-07 30.3 0.1 2.4e-05 23.7 0.1 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain PUF PF00806.14 EMR70873.1 - 8.2e-25 84.8 0.0 0.0015 17.9 0.0 6.0 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EMR70873.1 - 3.1e-13 49.1 0.0 6.9e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR70873.1 - 1.8e-06 27.6 0.0 3.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR70873.1 - 7.3e-06 25.8 0.0 1.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_M28 PF04389.12 EMR70874.1 - 1e-16 61.1 0.0 1.3e-16 60.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M28 Pkinase PF00069.20 EMR70875.1 - 4.7e-47 160.3 0.0 2e-43 148.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR70875.1 - 1.5e-32 112.7 0.0 6.3e-31 107.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR70875.1 - 8.9e-06 24.8 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EMR70875.1 - 0.00087 18.2 0.1 0.002 17.0 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EMR70875.1 - 0.035 12.9 0.1 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EMR70875.1 - 0.065 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tyrosinase PF00264.15 EMR70876.1 - 1.3e-48 166.1 0.0 3.2e-48 164.8 0.0 1.7 3 0 0 3 3 3 1 Common central domain of tyrosinase Mem_trans PF03547.13 EMR70877.1 - 8e-51 172.5 0.0 1.6e-50 171.5 0.0 1.4 1 1 0 1 1 1 1 Membrane transport protein Asp PF00026.18 EMR70879.1 - 2.4e-60 204.4 0.2 2.9e-60 204.1 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMR70879.1 - 9.1e-05 22.4 0.1 0.00097 19.1 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EMR70879.1 - 0.004 16.7 0.0 0.076 12.5 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Big_3_2 PF12245.3 EMR70879.1 - 0.033 13.7 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) AT_hook PF02178.14 EMR70880.1 - 0.017 14.7 4.0 0.017 14.7 2.7 3.5 2 0 0 2 2 2 0 AT hook motif SlyX PF04102.7 EMR70881.1 - 5.1e-05 23.5 1.5 0.00047 20.4 0.1 2.1 2 0 0 2 2 2 1 SlyX COG2 PF06148.6 EMR70881.1 - 0.0089 15.8 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF16 PF01519.11 EMR70881.1 - 0.022 14.9 0.4 0.033 14.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 ADIP PF11559.3 EMR70881.1 - 0.023 14.6 1.1 0.023 14.6 0.8 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cluap1 PF10234.4 EMR70881.1 - 0.026 13.7 0.5 0.038 13.1 0.3 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Menin PF05053.8 EMR70881.1 - 0.037 12.2 4.9 0.046 11.8 3.4 1.0 1 0 0 1 1 1 0 Menin TMF_DNA_bd PF12329.3 EMR70881.1 - 0.05 13.4 1.4 0.05 13.4 0.9 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4510 PF14971.1 EMR70881.1 - 0.051 13.7 4.0 0.069 13.3 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) Med9 PF07544.8 EMR70881.1 - 0.06 13.0 1.3 0.12 12.1 0.9 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Bacillus_HBL PF05791.6 EMR70881.1 - 0.062 12.6 0.1 0.074 12.4 0.1 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) OEP PF02321.13 EMR70881.1 - 0.072 12.6 5.3 0.13 11.8 3.7 1.4 1 1 0 1 1 1 0 Outer membrane efflux protein Fib_alpha PF08702.5 EMR70881.1 - 0.072 13.2 0.4 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Herpes_UL6 PF01763.11 EMR70881.1 - 0.077 11.1 0.4 0.088 10.9 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF241 PF03087.9 EMR70881.1 - 0.081 12.4 1.2 0.11 11.9 0.8 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function TBPIP PF07106.8 EMR70881.1 - 0.082 12.4 0.9 0.13 11.7 0.6 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Striatin PF08232.7 EMR70881.1 - 0.1 12.8 2.0 0.15 12.3 1.4 1.2 1 0 0 1 1 1 0 Striatin family Filament PF00038.16 EMR70881.1 - 0.12 11.8 5.3 0.069 12.6 2.5 1.5 1 1 0 1 1 1 0 Intermediate filament protein DUF4407 PF14362.1 EMR70881.1 - 0.12 11.3 6.0 0.13 11.1 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC84 PF14968.1 EMR70881.1 - 0.14 11.6 1.0 0.17 11.3 0.7 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 Viral_P18 PF04521.8 EMR70881.1 - 0.14 11.5 2.6 0.15 11.5 0.1 1.9 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Spc7 PF08317.6 EMR70881.1 - 0.15 10.6 2.2 0.21 10.2 1.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2360 PF10152.4 EMR70881.1 - 0.25 11.6 4.7 0.35 11.1 3.3 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DivIC PF04977.10 EMR70881.1 - 0.28 10.6 4.9 0.2 11.1 1.1 2.2 2 1 0 2 2 2 0 Septum formation initiator ATG16 PF08614.6 EMR70881.1 - 0.37 10.6 7.3 0.081 12.7 1.3 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EMR70881.1 - 0.46 10.0 3.6 0.72 9.4 2.5 1.4 1 1 0 1 1 1 0 IncA protein ISG65-75 PF11727.3 EMR70881.1 - 5.9 5.8 6.9 0.44 9.5 1.0 1.6 1 1 1 2 2 2 0 Invariant surface glycoprotein zf-TRAF PF02176.13 EMR70882.1 - 2.3e-13 50.2 42.8 7.4e-07 29.4 2.1 4.4 2 1 3 5 5 4 4 TRAF-type zinc finger zf-RING_5 PF14634.1 EMR70882.1 - 6.9e-07 28.8 4.0 6.9e-07 28.8 2.8 3.5 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EMR70882.1 - 5.1e-06 26.4 6.6 5.1e-06 26.4 4.6 3.3 2 1 2 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EMR70882.1 - 2.7e-05 23.9 7.4 2.7e-05 23.9 5.1 2.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EMR70882.1 - 3e-05 23.5 6.5 3e-05 23.5 4.5 3.7 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMR70882.1 - 3.6e-05 23.4 6.9 3.6e-05 23.4 4.8 3.0 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMR70882.1 - 0.00014 21.4 4.5 0.00014 21.4 3.1 3.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMR70882.1 - 0.00094 18.8 4.9 0.00094 18.8 3.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Sina PF03145.11 EMR70882.1 - 0.0025 17.5 2.1 0.0025 17.5 1.5 3.0 1 1 1 3 3 3 2 Seven in absentia protein family zf-RING_6 PF14835.1 EMR70882.1 - 0.032 13.9 1.3 0.032 13.9 0.9 2.1 2 0 0 2 2 1 0 zf-RING of BARD1-type protein TelA PF05816.6 EMR70882.1 - 0.074 11.7 0.2 0.19 10.3 0.0 1.6 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) U-box PF04564.10 EMR70882.1 - 0.34 10.8 1.8 1.6 8.7 0.0 2.9 4 0 0 4 4 3 0 U-box domain Exo_endo_phos PF03372.18 EMR70883.1 - 2.1e-07 31.1 0.3 2.1e-07 31.1 0.2 1.8 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF3089 PF11288.3 EMR70884.1 - 0.048 12.8 0.0 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Trypan_PARP PF05887.6 EMR70884.1 - 2.9 7.7 10.2 3.9 7.2 7.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) OPT PF03169.10 EMR70885.1 - 1.5e-56 192.1 3.8 1.7e-56 191.9 2.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Yip1 PF04893.12 EMR70885.1 - 2.7 7.4 15.2 26 4.2 10.5 2.3 1 1 0 1 1 1 0 Yip1 domain YbgT_YccB PF08173.6 EMR70885.1 - 9 6.2 9.1 1.6 8.5 1.8 2.7 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Piwi PF02171.12 EMR70886.1 - 1.3e-79 267.3 1.3 2e-79 266.7 0.9 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EMR70886.1 - 2.4e-14 52.3 0.0 2.3e-13 49.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EMR70886.1 - 1.4e-13 50.3 0.3 3.9e-13 48.8 0.2 1.7 1 1 0 1 1 1 1 PAZ domain Suf PF05843.9 EMR70887.1 - 2e-52 178.6 10.8 4.2e-51 174.3 0.1 3.7 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EMR70887.1 - 1.7e-05 25.0 3.5 0.0062 17.0 0.0 5.5 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR70887.1 - 0.0001 22.5 0.7 0.068 13.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMR70887.1 - 0.00067 20.2 0.3 0.0058 17.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat PP2C_C PF07830.8 EMR70887.1 - 0.068 13.2 0.0 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain HAT PF02184.11 EMR70887.1 - 0.092 12.5 2.6 0.16 11.7 0.0 2.8 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat zf-C2H2_6 PF13912.1 EMR70888.1 - 0.0043 16.8 0.1 0.0043 16.8 0.0 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger TGT PF01702.13 EMR70888.1 - 0.014 14.7 0.3 0.02 14.2 0.2 1.1 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase zf-C2H2_2 PF12756.2 EMR70888.1 - 0.15 12.1 6.2 0.73 9.9 3.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_5 PF13719.1 EMR70888.1 - 0.47 10.0 3.3 5.5 6.6 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.1 EMR70888.1 - 1.3 9.4 8.6 11 6.6 2.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMR70888.1 - 1.8 8.9 7.4 3.9 7.9 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain AMMECR1 PF01871.12 EMR70889.1 - 5.9e-45 152.4 0.0 2.3e-44 150.5 0.0 1.7 2 0 0 2 2 2 1 AMMECR1 SR-25 PF10500.4 EMR70889.1 - 1 8.8 6.1 1.5 8.2 4.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ras PF00071.17 EMR70890.1 - 1.1e-39 135.4 0.0 3.3e-25 88.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EMR70890.1 - 6.9e-12 45.9 0.0 1.2e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMR70890.1 - 0.0049 16.8 0.0 0.0068 16.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EMR70890.1 - 0.0072 15.5 0.0 0.024 13.8 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family PRK PF00485.13 EMR70890.1 - 0.033 13.7 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GTP_EFTU PF00009.22 EMR70890.1 - 0.068 12.5 0.0 1.3 8.4 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EMR70890.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF2207 PF09972.4 EMR70891.1 - 0.13 10.8 0.2 0.19 10.2 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF455 PF04305.9 EMR70892.1 - 6.4e-89 297.5 0.3 7.2e-89 297.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF455) ASF1_hist_chap PF04729.8 EMR70893.1 - 3.6e-67 224.8 0.0 4.7e-67 224.4 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF2531 PF10748.4 EMR70894.1 - 0.17 11.0 4.1 0.089 11.9 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2531) FYDLN_acid PF09538.5 EMR70894.1 - 0.99 10.0 12.8 1.2 9.7 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF1510 PF07423.6 EMR70894.1 - 3 7.1 15.0 3.3 7.0 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PAT1 PF09770.4 EMR70894.1 - 3.9 5.5 11.5 4.2 5.4 8.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PTR2 PF00854.16 EMR70895.1 - 3.2e-12 45.9 1.5 4.6e-12 45.4 1.1 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 EMR70895.1 - 2.9e-05 22.9 4.1 3.7e-05 22.6 2.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Asp PF00026.18 EMR70896.1 - 2.7e-61 207.5 2.6 3.8e-61 207.0 0.3 2.0 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMR70896.1 - 5.5e-06 26.4 0.1 1.7e-05 24.8 0.1 2.0 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EMR70896.1 - 0.00016 22.1 0.3 0.51 10.8 0.0 3.9 4 1 0 4 4 4 2 Aspartyl protease Transcript_VP30 PF11507.3 EMR70897.1 - 0.072 12.9 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 AAA PF00004.24 EMR70898.1 - 4.7e-13 49.4 0.0 1.2e-12 48.1 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EMR70898.1 - 0.0036 17.0 0.1 0.024 14.3 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain Vps36_ESCRT-II PF11605.3 EMR70898.1 - 0.015 15.0 0.0 0.57 10.0 0.0 2.4 2 1 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 AAA_22 PF13401.1 EMR70898.1 - 0.053 13.6 0.6 21 5.2 0.1 2.9 1 1 1 3 3 3 0 AAA domain AAA_5 PF07728.9 EMR70898.1 - 0.1 12.3 0.1 0.99 9.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) CTP_transf_1 PF01148.15 EMR70899.1 - 1.1e-08 35.0 11.8 9.4e-08 32.0 5.3 2.6 2 1 0 2 2 2 1 Cytidylyltransferase family Tannase PF07519.6 EMR70900.1 - 6.2e-109 364.8 0.1 7.6e-109 364.5 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EMR70900.1 - 0.00073 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR70900.1 - 0.005 16.6 0.0 3.5 7.3 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR70900.1 - 0.06 12.8 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold BBE PF08031.7 EMR70901.1 - 7.4e-11 41.7 0.5 1.6e-10 40.6 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like Hce2 PF14856.1 EMR70902.1 - 0.005 16.7 0.4 0.0071 16.2 0.3 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor adh_short PF00106.20 EMR70903.1 - 4e-12 46.3 3.5 6e-12 45.7 2.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR70903.1 - 6.5e-07 29.1 0.9 1.1e-06 28.4 0.6 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR70903.1 - 0.0037 17.0 0.0 0.0052 16.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase p450 PF00067.17 EMR70904.1 - 2.3e-68 230.8 0.0 2.8e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.23 EMR70905.1 - 8.8e-05 21.9 0.8 0.00017 21.0 0.6 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase UbiA PF01040.13 EMR70906.1 - 3.7e-23 82.0 11.1 5.1e-23 81.5 7.6 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family FAD_binding_3 PF01494.14 EMR70909.1 - 3.4e-56 190.8 0.0 4.1e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR70909.1 - 5.1e-11 42.0 2.0 2.4e-06 26.7 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR70909.1 - 4e-06 25.9 1.1 4.7e-05 22.4 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EMR70909.1 - 1.4e-05 23.7 0.8 3.9e-05 22.2 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EMR70909.1 - 3.2e-05 23.8 0.3 0.00017 21.5 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR70909.1 - 7.3e-05 22.7 0.7 0.00063 19.6 0.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR70909.1 - 8e-05 22.9 0.1 0.034 14.5 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR70909.1 - 0.00035 19.7 0.3 0.00055 19.1 0.2 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EMR70909.1 - 0.0024 16.8 0.3 0.0039 16.1 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.13 EMR70909.1 - 0.0043 16.7 0.2 0.0081 15.8 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EMR70909.1 - 0.0044 16.4 0.2 0.0076 15.6 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 EMR70909.1 - 0.0071 16.4 0.1 0.02 14.9 0.1 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMR70909.1 - 0.014 14.4 1.4 0.039 13.0 1.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EMR70909.1 - 0.019 14.9 0.1 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 EMR70909.1 - 0.028 14.6 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EMR70909.1 - 0.07 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding ThiF PF00899.16 EMR70909.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 ThiF family F420_oxidored PF03807.12 EMR70909.1 - 0.12 12.8 0.2 0.29 11.5 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_4 PF01565.18 EMR70910.1 - 1.2e-16 60.4 0.9 1.2e-16 60.4 0.6 1.7 2 0 0 2 2 2 1 FAD binding domain APH PF01636.18 EMR70911.1 - 1.4e-12 47.8 0.0 2.2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMR70911.1 - 0.00011 21.8 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EMR70911.1 - 0.016 14.5 0.0 0.17 11.1 0.0 2.2 2 1 0 2 2 2 0 RIO1 family DUF1679 PF07914.6 EMR70911.1 - 0.026 13.1 0.0 0.53 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF4135 PF13575.1 EMR70911.1 - 0.092 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Pkinase PF00069.20 EMR70911.1 - 0.12 11.4 0.0 0.76 8.8 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain EcKinase PF02958.15 EMR70911.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase FAD_binding_3 PF01494.14 EMR70912.1 - 9.4e-25 87.3 0.0 9.3e-16 57.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR70912.1 - 7.5e-06 25.0 0.1 0.0094 14.8 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR70912.1 - 0.00012 22.0 0.1 0.00036 20.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR70912.1 - 0.00017 21.5 0.2 0.00073 19.4 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMR70912.1 - 0.00039 19.1 0.0 0.034 12.7 0.0 2.5 3 0 0 3 3 3 1 Tryptophan halogenase Thi4 PF01946.12 EMR70912.1 - 0.00099 18.2 0.0 0.0037 16.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EMR70912.1 - 0.0021 16.9 0.0 0.0034 16.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EMR70912.1 - 0.0049 15.7 0.0 0.25 10.1 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.19 EMR70912.1 - 0.0051 15.9 0.0 0.4 9.6 0.0 2.4 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase TrkA_N PF02254.13 EMR70912.1 - 0.013 15.4 0.0 0.041 13.8 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.9 EMR70912.1 - 0.021 13.2 0.1 0.036 12.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 EMR70912.1 - 0.11 11.3 0.0 4.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein p450 PF00067.17 EMR70914.1 - 3.1e-17 62.2 0.2 2.6e-13 49.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 EMR70918.1 - 2.7e-24 85.5 46.7 2.7e-24 85.5 32.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Myb_DNA-binding PF00249.26 EMR70919.1 - 2.1e-18 66.0 0.6 1.8e-12 47.1 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMR70919.1 - 4.2e-18 65.2 1.7 5.8e-13 48.7 0.1 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Ank_2 PF12796.2 EMR70920.1 - 0.00026 21.2 0.0 0.054 13.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMR70920.1 - 0.00054 19.6 0.0 0.16 11.8 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat NPP1 PF05630.6 EMR70921.1 - 8.6e-80 267.3 2.9 1e-79 267.1 2.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Zn_clus PF00172.13 EMR70922.1 - 9e-05 22.3 14.8 0.00017 21.4 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 EMR70923.1 - 0.0047 17.2 4.0 0.4 11.1 0.0 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR70923.1 - 0.0052 17.0 12.2 0.028 14.7 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger NST1 PF13945.1 EMR70923.1 - 0.25 11.3 3.4 0.4 10.7 2.3 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Pkinase PF00069.20 EMR70924.1 - 4.9e-57 193.0 0.0 8e-57 192.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR70924.1 - 8.9e-27 93.7 0.0 1.4e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR70924.1 - 0.0063 15.5 0.0 0.023 13.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMR70924.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EMR70924.1 - 0.12 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Ribosomal_L1 PF00687.16 EMR70925.1 - 6.2e-52 176.1 0.2 7.3e-52 175.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Amino_oxidase PF01593.19 EMR70927.1 - 8e-31 107.5 0.0 3.5e-20 72.5 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMR70927.1 - 1.1e-08 35.0 0.0 2.8e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR70927.1 - 0.0045 17.0 0.0 0.015 15.3 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMR70927.1 - 0.11 11.5 0.0 0.3 10.1 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain NTR2 PF15458.1 EMR70928.1 - 2e-58 197.6 5.0 2e-58 197.6 3.5 1.9 2 0 0 2 2 2 1 Nineteen complex-related protein 2 MFS_1 PF07690.11 EMR70930.1 - 1.3e-19 70.1 34.7 1.5e-12 46.9 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pollen_allerg_1 PF01357.16 EMR70931.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Pollen allergen DAO PF01266.19 EMR70933.1 - 6.3e-31 107.5 0.0 6.4e-28 97.6 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR70933.1 - 9.8e-08 31.2 0.2 2e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EMR70933.1 - 1.8e-07 30.5 0.0 3.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EMR70933.1 - 7.9e-07 29.3 0.1 3.6e-06 27.1 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EMR70933.1 - 1.2e-06 27.9 0.0 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR70933.1 - 3.1e-06 25.9 0.1 6.9e-06 24.7 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EMR70933.1 - 5.7e-06 26.2 0.0 5.7e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR70933.1 - 3e-05 23.9 0.0 5.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR70933.1 - 3.9e-05 23.9 0.2 0.00018 21.8 0.1 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR70933.1 - 8.5e-05 21.5 0.1 0.00013 20.9 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EMR70933.1 - 9.4e-05 21.6 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 EMR70933.1 - 0.006 16.8 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EMR70933.1 - 0.0068 15.3 0.1 0.011 14.6 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.13 EMR70933.1 - 0.041 13.5 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDI PF00996.13 EMR70933.1 - 0.059 11.6 0.0 0.085 11.1 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor DUF3844 PF12955.2 EMR70934.1 - 3.2e-32 110.6 2.0 3.2e-32 110.6 1.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) TFIIF_alpha PF05793.7 EMR70934.1 - 9 4.5 9.3 14 3.8 6.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LSM PF01423.17 EMR70935.1 - 2.6e-18 65.3 0.7 3.3e-18 65.0 0.5 1.1 1 0 0 1 1 1 1 LSM domain GMC_oxred_C PF05199.8 EMR70936.1 - 1.6e-36 125.7 0.1 2.7e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR70936.1 - 7.3e-31 107.4 0.0 9e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DUF3716 PF12511.3 EMR70937.1 - 5.1e-07 29.2 6.4 8.3e-07 28.5 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) FeS PF04060.8 EMR70937.1 - 0.2 11.2 5.5 0.19 11.2 0.7 2.6 2 0 0 2 2 2 0 Putative Fe-S cluster Zn_clus PF00172.13 EMR70937.1 - 8.9 6.3 11.8 1.6e+02 2.2 8.1 2.5 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EMR70938.1 - 1.6e-16 60.3 0.0 2e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Mito_fiss_reg PF05308.6 EMR70939.1 - 0.23 10.7 4.5 0.35 10.2 3.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Pkinase PF00069.20 EMR70940.1 - 1.9e-38 132.1 0.0 2.3e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR70940.1 - 1e-13 50.9 0.0 1.4e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMR70940.1 - 2.1e-05 24.3 0.0 0.002 17.9 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EMR70940.1 - 0.062 12.0 0.1 0.093 11.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF4349 PF14257.1 EMR70940.1 - 2.9 7.0 5.5 4.3 6.4 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) RNR_inhib PF08591.5 EMR70941.1 - 4.4e-21 75.6 0.7 1.9e-20 73.5 0.5 2.1 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor TPR_12 PF13424.1 EMR70942.1 - 8.4e-34 115.3 15.0 1.1e-12 47.7 0.2 4.2 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 EMR70942.1 - 4.3e-24 83.6 7.9 1.2e-07 31.4 0.0 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EMR70942.1 - 4.3e-11 42.4 2.4 0.052 14.1 0.0 5.4 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMR70942.1 - 3.7e-10 38.9 0.9 0.0088 15.8 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR70942.1 - 3.6e-09 36.8 0.5 0.0076 16.5 0.0 4.4 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EMR70942.1 - 9.1e-08 32.5 0.4 0.0043 17.6 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMR70942.1 - 5.6e-07 28.8 1.2 0.0051 16.5 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMR70942.1 - 3.1e-06 26.7 0.7 0.0028 17.2 0.1 3.4 3 1 0 4 4 4 1 TPR repeat TPR_4 PF07721.9 EMR70942.1 - 3.3e-06 26.9 2.0 0.12 12.9 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EMR70942.1 - 4e-05 23.6 0.1 0.0011 19.0 0.0 2.6 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EMR70942.1 - 4.8e-05 23.2 0.2 2.7 8.4 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMR70942.1 - 6.9e-05 23.0 2.6 7.6 7.2 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EMR70942.1 - 0.00019 21.0 0.1 0.18 11.2 0.0 3.0 2 1 1 3 3 3 1 Foie gras liver health family 1 PPR PF01535.15 EMR70942.1 - 0.00028 20.6 0.2 0.15 12.1 0.0 3.9 4 0 0 4 4 4 1 PPR repeat TPR_20 PF14561.1 EMR70942.1 - 0.0067 16.5 0.3 2.2 8.4 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat PPR_1 PF12854.2 EMR70942.1 - 0.052 13.0 1.3 0.49 9.9 0.0 2.9 3 0 0 3 3 3 0 PPR repeat TPR_1 PF00515.23 EMR70942.1 - 0.068 12.8 2.6 0.27 10.8 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 EMR70942.1 - 0.17 12.2 0.6 42 4.7 0.0 3.9 4 0 0 4 4 4 0 Pentatricopeptide repeat domain TPR_3 PF07720.7 EMR70942.1 - 0.36 10.6 2.3 22 4.9 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMR70942.1 - 2.5 8.0 4.7 8.2 6.4 0.1 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Phosducin PF02114.11 EMR70943.1 - 2.1e-14 52.9 0.1 2.8e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EMR70943.1 - 0.01 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin GMC_oxred_N PF00732.14 EMR70944.1 - 1.1e-54 185.6 0.0 1.8e-54 184.9 0.0 1.3 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR70944.1 - 6.8e-36 123.7 0.0 1.1e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMR70944.1 - 2.3e-06 26.7 0.9 0.0042 15.9 1.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR70944.1 - 0.00012 21.1 0.4 0.00021 20.3 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMR70944.1 - 0.00036 19.5 0.3 0.00052 19.0 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMR70944.1 - 0.0011 18.9 1.0 0.0027 17.7 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMR70944.1 - 0.0077 15.3 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EMR70944.1 - 0.014 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR70944.1 - 0.096 12.7 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMR70944.1 - 0.21 10.1 0.1 0.31 9.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 EMR70944.1 - 0.31 9.4 0.5 0.45 8.9 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein RTC PF01137.16 EMR70945.1 - 1.4e-34 118.9 0.0 9.3e-21 73.6 0.0 2.2 2 0 0 2 2 2 2 RNA 3'-terminal phosphate cyclase REV PF00424.13 EMR70945.1 - 1.2 9.0 9.4 15 5.5 0.6 3.6 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) Phosphodiest PF01663.17 EMR70946.1 - 3.9e-86 289.6 0.2 5.5e-86 289.1 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMR70946.1 - 0.0045 16.2 0.0 0.1 11.7 0.0 2.2 2 0 0 2 2 2 1 Sulfatase TRAP_alpha PF03896.11 EMR70946.1 - 4.9 6.0 7.6 13 4.6 5.2 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ribosomal_S27e PF01667.12 EMR70947.1 - 2.2e-28 97.5 7.4 2.7e-28 97.2 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EMR70947.1 - 0.021 14.7 1.3 0.023 14.5 0.9 1.2 1 0 0 1 1 1 0 IBR domain TF_Zn_Ribbon PF08271.7 EMR70947.1 - 0.29 10.4 3.3 0.41 10.0 2.3 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding LRR_4 PF12799.2 EMR70948.1 - 7.8e-09 34.9 11.6 1.3e-08 34.2 3.9 3.2 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMR70948.1 - 5e-05 22.9 9.9 8.9e-05 22.1 3.1 2.6 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 EMR70948.1 - 7e-05 22.3 9.9 0.11 12.6 0.1 4.4 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EMR70948.1 - 0.017 15.2 7.1 3.3 8.3 0.1 3.6 3 0 0 3 3 3 0 Leucine rich repeat ChaB PF06150.7 EMR70948.1 - 0.093 12.5 0.0 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 ChaB LRR_6 PF13516.1 EMR70948.1 - 1.1 9.5 5.0 20 5.6 0.5 3.2 3 0 0 3 3 3 0 Leucine Rich repeat FAD_binding_4 PF01565.18 EMR70949.1 - 5.5e-14 51.8 1.4 1.6e-13 50.2 0.9 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR70949.1 - 7e-13 48.2 0.0 1.4e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like tRNA-synt_2 PF00152.15 EMR70950.1 - 9.9e-72 241.5 0.0 1.3e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EMR70950.1 - 1.5e-07 31.1 0.0 2.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain NARP1 PF12569.3 EMR70950.1 - 1.5 7.4 3.9 2.3 6.9 2.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PBP PF01161.15 EMR70951.1 - 1.1e-15 57.7 0.0 1.4e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Microtub_bind PF13931.1 EMR70952.1 - 0.078 13.1 7.8 0.12 12.5 5.4 1.2 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding NST1 PF13945.1 EMR70952.1 - 0.27 11.3 6.6 0.48 10.4 4.6 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF605 PF04652.11 EMR70952.1 - 0.37 10.1 10.6 0.57 9.5 7.3 1.2 1 0 0 1 1 1 0 Vta1 like SWIM PF04434.12 EMR70952.1 - 0.68 9.4 4.1 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 SWIM zinc finger Acyl-thio_N PF12590.3 EMR70952.1 - 1.3 9.5 5.1 0.69 10.3 1.9 1.7 2 0 0 2 2 2 0 Acyl-ATP thioesterase Hid1 PF12722.2 EMR70952.1 - 2.8 5.5 7.7 3.8 5.0 5.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PROL5-SMR PF15621.1 EMR70952.1 - 6 7.3 7.7 16 5.9 5.3 1.8 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family ADK PF00406.17 EMR70953.1 - 2.1e-58 196.4 0.0 2.9e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EMR70953.1 - 1e-14 53.8 0.1 6.2e-14 51.3 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EMR70953.1 - 5.9e-06 27.0 0.1 1.1e-05 26.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMR70953.1 - 0.00019 21.3 0.0 0.00042 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMR70953.1 - 0.00098 19.4 0.1 0.003 17.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMR70953.1 - 0.0039 16.3 0.0 0.0069 15.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF1664 PF07889.7 EMR70953.1 - 0.25 11.1 1.2 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_GPD PF05954.6 EMR70954.1 - 0.057 12.6 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) MitMem_reg PF13012.1 EMR70956.1 - 1.9e-39 134.3 0.1 4.6e-39 133.0 0.0 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EMR70956.1 - 3.5e-29 100.8 0.0 8.2e-29 99.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease bZIP_1 PF00170.16 EMR70957.1 - 8.9e-08 31.9 9.8 1.4e-07 31.3 6.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EMR70957.1 - 7.2e-05 22.5 14.7 0.00012 21.8 9.1 1.9 1 1 1 2 2 2 1 Basic region leucine zipper CAF-1_p150 PF11600.3 EMR70957.1 - 0.004 16.5 3.5 0.0045 16.4 2.4 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal bZIP_Maf PF03131.12 EMR70957.1 - 0.01 16.0 6.4 0.016 15.4 4.5 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Takusan PF04822.8 EMR70957.1 - 0.014 15.1 0.8 0.014 15.1 0.6 1.9 3 0 0 3 3 3 0 Takusan MCC-bdg_PDZ PF10506.4 EMR70957.1 - 0.024 14.4 1.5 0.024 14.4 1.1 1.9 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome FAM92 PF06730.6 EMR70957.1 - 0.026 13.8 1.4 0.036 13.3 0.9 1.2 1 0 0 1 1 1 0 FAM92 protein Shugoshin_N PF07558.6 EMR70957.1 - 0.034 13.8 0.8 0.076 12.7 0.6 1.6 1 1 0 1 1 1 0 Shugoshin N-terminal coiled-coil region IncA PF04156.9 EMR70957.1 - 0.053 13.1 1.5 0.061 12.9 1.0 1.1 1 0 0 1 1 1 0 IncA protein DUF4407 PF14362.1 EMR70957.1 - 0.23 10.3 3.5 0.28 10.1 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 EMR70957.1 - 0.78 8.7 3.3 0.83 8.6 2.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 vMSA PF00695.14 EMR70957.1 - 0.79 8.8 2.4 0.77 8.8 1.7 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Atg14 PF10186.4 EMR70957.1 - 1.2 8.0 7.8 1.3 7.9 5.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HLH PF00010.21 EMR70957.1 - 1.3 8.7 6.5 19 5.0 4.5 2.4 1 1 0 1 1 1 0 Helix-loop-helix DNA-binding domain p450 PF00067.17 EMR70958.1 - 2.2e-40 138.5 0.0 3e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EMR70959.1 - 2.9e-24 85.4 32.2 3.7e-23 81.8 22.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR70959.1 - 1.1e-14 53.5 7.8 1.8e-14 52.9 5.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3522 PF12036.3 EMR70959.1 - 0.088 12.5 2.9 0.65 9.7 0.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3522) Clat_adaptor_s PF01217.15 EMR70961.1 - 5.9e-44 149.2 0.0 1.3e-43 148.1 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Beta-lactamase PF00144.19 EMR70962.1 - 2.6e-28 99.0 0.2 3.9e-28 98.4 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase RR_TM4-6 PF06459.7 EMR70963.1 - 0.73 9.6 9.7 1 9.2 6.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.9 EMR70963.1 - 2.5 7.7 6.0 3.3 7.3 4.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Herpes_DNAp_acc PF04929.7 EMR70963.1 - 9.6 5.0 8.4 12 4.6 5.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Glyco_trans_1_4 PF13692.1 EMR70965.1 - 7.8e-23 81.1 0.0 2.4e-22 79.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF3176 PF11374.3 EMR70966.1 - 2.6e-23 82.0 0.1 4.5e-23 81.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF3430 PF11912.3 EMR70967.1 - 0.00052 19.9 4.1 0.0011 18.8 2.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) VGCC_alpha2 PF08473.6 EMR70967.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd Mito_carr PF00153.22 EMR70968.1 - 1.2e-58 194.8 8.1 6e-20 70.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TCRP1 PF14944.1 EMR70969.1 - 1.4 8.8 5.8 1.3 8.8 3.5 1.4 1 1 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 Cation_efflux PF01545.16 EMR70970.1 - 1.4e-61 208.0 1.7 1.9e-61 207.6 1.1 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EMR70970.1 - 0.015 14.3 24.4 0.023 13.7 13.9 2.2 1 1 1 2 2 2 0 ZIP Zinc transporter DUF1469 PF07332.6 EMR70970.1 - 0.16 11.6 0.9 0.45 10.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Sugar_tr PF00083.19 EMR70971.1 - 9e-17 60.7 3.8 2.6e-16 59.2 0.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter DUF2892 PF11127.3 EMR70971.1 - 4.6 7.1 6.0 0.98 9.2 1.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) MFS_1 PF07690.11 EMR70972.1 - 2.2e-07 29.9 2.4 2.3e-07 29.8 1.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3262 PF11660.3 EMR70972.1 - 0.55 10.3 4.1 35 4.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) FA_desaturase PF00487.19 EMR70972.1 - 2.8 7.3 11.4 4.4 6.6 0.7 2.1 1 1 1 2 2 2 0 Fatty acid desaturase DUF4407 PF14362.1 EMR70972.1 - 7.1 5.4 6.7 1.2 8.0 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Peptidase_C13 PF01650.13 EMR70973.1 - 3.6e-41 141.1 0.2 5.3e-41 140.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family zf-TFIIIC PF12660.2 EMR70974.1 - 2e-08 34.0 0.6 1.7e-07 31.0 0.4 2.5 2 1 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.2 EMR70974.1 - 6.3e-08 32.5 0.3 3.1e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term UQ_con PF00179.21 EMR70975.1 - 4.3e-19 68.3 0.0 4.4e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Uso1_p115_head PF04869.9 EMR70976.1 - 7.1e-22 77.5 0.1 2.7e-12 46.0 0.1 2.8 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EMR70976.1 - 3e-06 27.2 38.2 3e-06 27.2 26.5 3.8 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Arm PF00514.18 EMR70976.1 - 0.018 14.8 0.1 0.13 12.1 0.0 2.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Spc7 PF08317.6 EMR70976.1 - 7.3 5.1 49.7 0.27 9.8 3.8 3.6 1 1 3 4 4 4 0 Spc7 kinetochore protein RasGAP PF00616.14 EMR70979.1 - 3.5e-47 160.6 0.1 7.7e-47 159.5 0.1 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase DUF1903 PF08991.5 EMR70979.1 - 0.02 15.0 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) XRN_N PF03159.13 EMR70980.1 - 3e-107 357.4 0.9 4e-107 357.0 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus DUF1675 PF07897.6 EMR70980.1 - 0.65 9.8 8.2 1.3 8.8 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) zf-CCHC PF00098.18 EMR70980.1 - 1.1 9.3 3.7 1.9 8.5 2.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Prp19 PF08606.6 EMR70981.1 - 3.6e-32 109.8 1.2 3.6e-32 109.8 0.9 1.6 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.27 EMR70981.1 - 2.9e-15 55.4 1.5 9e-05 22.2 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EMR70981.1 - 4e-06 26.4 2.4 0.027 13.9 0.0 2.3 1 1 1 2 2 2 2 PQQ-like domain VID27 PF08553.5 EMR70981.1 - 0.00034 19.0 0.1 0.00082 17.7 0.0 1.6 1 0 0 1 1 1 1 VID27 cytoplasmic protein zf-Nse PF11789.3 EMR70981.1 - 0.0028 17.1 0.0 0.0057 16.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EMR70981.1 - 0.04 13.8 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 U-box domain DUF3312 PF11768.3 EMR70981.1 - 0.13 10.4 0.0 0.26 9.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Aldo_ket_red PF00248.16 EMR70982.1 - 2.9e-60 203.4 0.0 3.3e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AIRC PF00731.15 EMR70983.1 - 2.6e-64 215.0 0.9 5.7e-64 213.9 0.6 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EMR70983.1 - 2.2e-49 167.1 0.0 4e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EMR70983.1 - 1.9e-11 44.0 0.0 3.9e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EMR70983.1 - 4.6e-05 22.9 0.0 0.00061 19.2 0.0 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus PrpR_N PF06506.6 EMR70983.1 - 0.0025 17.2 0.1 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 Propionate catabolism activator 2-Hacid_dh_C PF02826.14 EMR70983.1 - 0.03 13.4 0.1 0.072 12.2 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 EMR70983.1 - 0.037 14.3 0.0 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain ATPgrasp_Ter PF15632.1 EMR70983.1 - 0.12 11.0 0.0 0.32 9.7 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Acetyltransf_7 PF13508.1 EMR70984.1 - 5.1e-07 29.7 0.0 7.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EMR70984.1 - 6.8e-07 29.2 0.0 9e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EMR70984.1 - 0.0068 16.2 0.0 0.0094 15.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR70984.1 - 0.0086 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMR70984.1 - 0.097 12.8 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_25 PF01755.12 EMR70985.1 - 2.7e-12 46.7 0.0 1.3e-10 41.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) WD40 PF00400.27 EMR70986.1 - 4.6e-52 172.1 20.2 3.1e-11 42.6 1.5 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.6 EMR70986.1 - 1.6e-12 46.4 2.2 1.6e-12 46.4 1.5 2.1 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 EMR70986.1 - 0.014 14.5 0.0 0.55 9.2 0.0 2.4 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 EMR70986.1 - 0.052 13.2 0.0 0.71 9.5 0.0 2.7 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A PAN_1 PF00024.21 EMR70988.1 - 0.025 14.3 4.4 0.037 13.7 1.5 2.6 2 1 0 2 2 2 0 PAN domain PAN_4 PF14295.1 EMR70988.1 - 0.051 13.2 7.0 0.19 11.4 4.9 2.0 1 1 0 1 1 1 0 PAN domain SUZ-C PF12901.2 EMR70989.1 - 3.3e-05 23.3 0.7 8.8e-05 22.0 0.5 1.8 1 0 0 1 1 1 1 SUZ-C motif SUZ PF12752.2 EMR70989.1 - 0.00055 20.4 12.0 0.004 17.6 8.3 2.5 1 1 0 1 1 1 1 SUZ domain Ycf1 PF05758.7 EMR70989.1 - 0.12 10.0 0.2 0.15 9.7 0.1 1.1 1 0 0 1 1 1 0 Ycf1 Spt5_N PF11942.3 EMR70989.1 - 0.65 10.6 14.2 12 6.6 0.0 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF3043 PF11241.3 EMR70989.1 - 2.2 7.8 5.9 4 6.9 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) CAF-1_p150 PF11600.3 EMR70989.1 - 3.4 6.9 16.3 1.7 7.9 9.8 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1996 PF09362.5 EMR70990.1 - 1.1e-67 228.1 2.0 1.4e-67 227.8 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Pkinase PF00069.20 EMR70991.1 - 2.7e-64 216.8 0.0 3.2e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR70991.1 - 1.2e-28 99.9 0.0 1.6e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EMR70991.1 - 0.00082 19.8 2.1 0.0018 18.7 1.4 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMR70991.1 - 0.028 13.3 0.0 0.069 12.0 0.0 1.5 1 1 1 2 2 2 0 Kinase-like APH PF01636.18 EMR70991.1 - 0.098 12.3 0.2 1 9.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DNase_NucA_NucB PF14040.1 EMR70992.1 - 1.3e-05 25.2 0.2 4.3e-05 23.6 0.0 1.9 1 1 1 2 2 2 1 Deoxyribonuclease NucA/NucB DUF2897 PF11446.3 EMR70993.1 - 1.2 9.0 0.0 1.2 9.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2897) Cyclin_N PF00134.18 EMR70995.1 - 0.00021 20.8 0.7 0.00036 20.0 0.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain SNF2_N PF00176.18 EMR70996.1 - 5.8e-25 87.7 0.2 9.1e-21 73.9 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain DEAD PF00270.24 EMR70996.1 - 3e-05 23.5 0.0 6.6e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR70996.1 - 0.00077 19.2 0.0 0.0021 17.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4246 PF14033.1 EMR70997.1 - 8.4e-174 578.8 0.6 1.1e-173 578.5 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EMR70997.1 - 0.018 15.3 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Dus PF01207.12 EMR70998.1 - 1.3e-32 112.9 0.0 4.9e-24 84.7 0.0 3.5 3 1 0 3 3 3 3 Dihydrouridine synthase (Dus) Neisseria_TspB PF05616.8 EMR70998.1 - 3.3 5.9 6.2 5.7 5.1 4.3 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein ATP_sub_h PF10775.4 EMR71000.1 - 6.8e-26 89.7 0.7 1.2e-25 88.9 0.5 1.4 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EMR71000.1 - 0.037 13.9 0.1 0.058 13.2 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Methyltransf_16 PF10294.4 EMR71001.1 - 2e-15 56.6 0.0 2.9e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 EMR71001.1 - 0.0023 17.6 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR71001.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EMR71002.1 - 2.8e-29 101.9 36.2 8e-29 100.4 25.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TPR_11 PF13414.1 EMR71003.1 - 2.9e-05 23.6 0.1 0.039 13.5 0.0 2.6 2 0 0 2 2 2 2 TPR repeat GFA PF04828.9 EMR71004.1 - 3.1e-10 39.8 0.0 3.5e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EMR71004.1 - 4.8 6.7 6.4 0.29 10.6 0.5 1.8 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Glyco_hydro_3 PF00933.16 EMR71005.1 - 8.2e-86 287.6 0.0 1.2e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR71005.1 - 1.1e-51 175.5 0.3 9e-51 172.5 0.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR71005.1 - 2.8e-24 84.8 0.0 5e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Pkinase PF00069.20 EMR71006.1 - 1.5e-71 240.6 0.0 2e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR71006.1 - 3.7e-32 111.4 0.0 5.1e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EMR71006.1 - 3.7e-13 49.7 3.6 1.1e-12 48.2 2.5 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EMR71006.1 - 8.9e-10 37.9 0.0 2.8e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EMR71006.1 - 0.0099 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EMR71006.1 - 0.034 13.7 0.1 0.065 12.7 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EMR71006.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EMR71006.1 - 0.06 12.6 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL C2 PF00168.25 EMR71006.1 - 0.066 13.0 0.0 0.29 10.9 0.0 2.1 1 1 0 1 1 1 0 C2 domain FAD_binding_3 PF01494.14 EMR71007.1 - 1.8e-64 218.0 0.0 2.5e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EMR71007.1 - 4.9e-07 29.8 0.0 0.00033 20.6 0.0 3.2 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR71007.1 - 0.00022 20.2 0.1 0.13 11.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR71007.1 - 0.00026 21.1 0.0 0.003 17.6 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fe_hyd_lg_C PF02906.9 EMR71008.1 - 8.6e-60 202.4 0.0 2.3e-59 200.9 0.0 1.7 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fungal_trans PF04082.13 EMR71009.1 - 5.1e-14 51.7 0.0 1.8e-13 49.9 0.0 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2427 PF10348.4 EMR71010.1 - 7.3e-07 28.7 5.0 1.5e-06 27.6 3.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DOMON PF03351.12 EMR71010.1 - 3.4e-05 23.7 0.5 8.4e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 DOMON domain RAP1 PF07218.6 EMR71010.1 - 8.4 4.3 4.8 11 3.9 3.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RNase_H PF00075.19 EMR71011.1 - 7.4e-16 58.6 0.0 9.8e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EMR71011.1 - 0.0023 17.6 0.1 0.16 11.7 0.0 2.3 2 1 0 2 2 2 1 Reverse transcriptase-like UPF0058 PF01893.11 EMR71011.1 - 0.084 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0058 YpM PF09144.5 EMR71011.1 - 0.14 12.0 0.7 0.44 10.5 0.2 1.9 1 1 1 2 2 2 0 Yersinia pseudotuberculosis mitogen CorA PF01544.13 EMR71012.1 - 7.7e-08 31.7 7.4 4.6e-07 29.1 0.9 2.7 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Nop14 PF04147.7 EMR71013.1 - 0.79 7.5 5.4 1.4 6.7 3.8 1.3 1 0 0 1 1 1 0 Nop14-like family PH_9 PF15410.1 EMR71014.1 - 0.00023 21.2 0.0 0.00054 20.0 0.0 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EMR71014.1 - 0.00091 19.4 0.1 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 PH domain adh_short PF00106.20 EMR71015.1 - 3.8e-22 78.9 0.1 4.3e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR71015.1 - 9.1e-12 45.0 0.1 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR71015.1 - 2.3e-11 43.9 0.0 2.8e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.10 EMR71015.1 - 0.0084 15.7 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Epimerase PF01370.16 EMR71015.1 - 0.024 14.0 0.1 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EMR71015.1 - 0.03 13.9 0.1 0.039 13.6 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EMR71015.1 - 0.042 13.7 0.8 0.089 12.6 0.3 1.7 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glyco_hydro_16 PF00722.16 EMR71016.1 - 2.6e-08 33.3 1.1 3.8e-08 32.8 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DNA_pol_lambd_f PF10391.4 EMR71017.1 - 1.4e-21 75.7 0.9 2.5e-21 74.9 0.6 1.4 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 EMR71017.1 - 4.8e-20 71.6 0.0 9.2e-20 70.7 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EMR71017.1 - 6.2e-20 70.6 0.0 1e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_5 PF14520.1 EMR71017.1 - 0.0075 16.4 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EMR71017.1 - 0.012 15.8 0.0 0.033 14.5 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain TFIIE_alpha PF02002.12 EMR71018.1 - 2.4e-16 59.1 0.5 5.3e-16 58.0 0.4 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit CDV3 PF15359.1 EMR71018.1 - 0.011 15.8 7.4 0.011 15.8 5.1 2.3 2 1 0 2 2 2 0 Carnitine deficiency-associated protein 3 PBP_sp32 PF07222.7 EMR71018.1 - 3.8 6.6 12.9 6.9 5.7 8.9 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Nop14 PF04147.7 EMR71018.1 - 4.3 5.1 23.3 6.4 4.5 16.2 1.2 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 EMR71018.1 - 5.7 6.0 22.7 37 3.3 15.6 2.3 1 1 0 1 1 1 0 Myc amino-terminal region WD40 PF00400.27 EMR71019.1 - 9.4e-26 88.7 0.4 7.5e-07 28.7 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 EMR71019.1 - 2e-06 27.6 0.1 5.4e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A MAPEG PF01124.13 EMR71020.1 - 1.3e-23 82.9 3.0 1.5e-23 82.7 2.1 1.0 1 0 0 1 1 1 1 MAPEG family Acetyltransf_1 PF00583.19 EMR71022.1 - 2.2e-17 62.8 0.0 3e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR71022.1 - 1.6e-08 34.5 0.0 2.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR71022.1 - 1.3e-07 31.2 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EMR71022.1 - 3e-06 27.3 0.0 4.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMR71022.1 - 2.6e-05 24.1 0.1 3.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMR71022.1 - 0.0019 18.1 0.1 0.0038 17.1 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR71022.1 - 0.0053 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_M14 PF00246.19 EMR71023.1 - 8.1e-60 202.7 0.0 1.2e-59 202.2 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase ECR1_N PF14382.1 EMR71025.1 - 5.1e-11 41.6 0.1 1.2e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EMR71025.1 - 0.061 13.2 0.0 0.74 9.8 0.0 2.3 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 G-alpha PF00503.15 EMR71026.1 - 2.5e-116 388.5 0.3 3e-116 388.2 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EMR71026.1 - 1.3e-13 50.5 0.4 1.2e-08 34.4 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EMR71026.1 - 0.00053 19.1 0.2 0.1 11.6 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 EMR71026.1 - 0.025 13.9 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMR71026.1 - 0.041 13.4 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EMR71026.1 - 0.14 11.5 0.0 4.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Cyt-b5 PF00173.23 EMR71027.1 - 3.2e-14 52.4 0.2 3.8e-14 52.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L22e PF01776.12 EMR71028.1 - 2.6e-46 156.2 0.9 3.2e-46 155.9 0.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family START PF01852.14 EMR71028.1 - 0.1 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 START domain SKG6 PF08693.5 EMR71029.1 - 0.018 14.3 0.2 0.041 13.2 0.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3611 PF12263.3 EMR71029.1 - 0.056 12.8 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Defensin_4 PF07936.7 EMR71029.1 - 7.3 6.3 6.4 14 5.4 0.2 2.9 3 0 0 3 3 3 0 Potassium-channel blocking toxin IncA PF04156.9 EMR71030.1 - 3.1 7.3 7.6 5.9 6.4 5.3 1.6 1 1 0 1 1 1 0 IncA protein Glyco_hydro_3 PF00933.16 EMR71031.1 - 7.1e-90 301.0 0.0 9.7e-90 300.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR71031.1 - 1.2e-20 73.9 0.0 6.1e-17 61.8 0.0 2.6 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR71031.1 - 5.8e-20 70.9 0.0 1.3e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Spermine_synth PF01564.12 EMR71033.1 - 1.4e-96 322.2 0.0 1.8e-96 321.8 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EMR71033.1 - 5.9e-05 23.6 0.0 0.0001 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR71033.1 - 0.00017 21.1 0.0 0.00026 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR71033.1 - 0.0022 17.7 0.0 0.01 15.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 EMR71033.1 - 0.0085 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 EMR71033.1 - 0.021 15.2 0.6 0.091 13.2 0.1 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.13 EMR71033.1 - 0.093 11.9 0.2 1 8.5 0.1 2.3 1 1 2 3 3 3 0 O-methyltransferase CN_hydrolase PF00795.17 EMR71034.1 - 4.5e-30 104.3 0.0 6.7e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Formyl_trans_N PF00551.14 EMR71035.1 - 4e-34 117.7 0.0 5.1e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Fungal_trans PF04082.13 EMR71036.1 - 4.8e-09 35.4 0.0 2e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain CN_hydrolase PF00795.17 EMR71038.1 - 4.9e-14 52.0 0.0 9.7e-14 51.1 0.0 1.5 1 1 1 2 2 2 1 Carbon-nitrogen hydrolase Ran_BP1 PF00638.13 EMR71039.1 - 1.2e-13 51.1 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 EMR71039.1 - 0.01 16.0 28.9 0.01 16.0 20.1 11.1 2 1 7 10 10 10 0 Nucleoporin FG repeat region Aldedh PF00171.17 EMR71040.1 - 2.4e-74 250.3 0.0 3e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pex24p PF06398.6 EMR71041.1 - 2e-89 299.9 0.0 2.5e-89 299.5 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.7 EMR71041.1 - 0.0026 16.0 0.1 0.0042 15.3 0.1 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) DUF3292 PF11696.3 EMR71041.1 - 0.0035 15.3 0.3 0.0061 14.4 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3292) PRT_C PF08372.5 EMR71041.1 - 0.076 12.5 1.0 0.15 11.5 0.3 1.7 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal SPX PF03105.14 EMR71042.1 - 1.7e-21 77.2 9.7 1e-14 54.9 0.0 3.1 2 2 1 3 3 3 2 SPX domain Mito_fiss_reg PF05308.6 EMR71042.1 - 0.13 11.6 4.5 0.21 10.9 3.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Lamp PF01299.12 EMR71042.1 - 0.14 11.3 2.1 0.21 10.7 1.4 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) MscS_porin PF12795.2 EMR71042.1 - 0.8 8.9 4.3 0.62 9.3 1.1 2.1 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain TPR_12 PF13424.1 EMR71043.1 - 6.3e-11 42.0 3.6 0.00034 20.4 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMR71043.1 - 6.2e-07 28.9 2.5 0.0099 15.5 0.1 3.3 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EMR71043.1 - 2.5e-06 26.9 1.8 0.018 14.9 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EMR71043.1 - 1.3e-05 24.5 0.0 1.8 8.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EMR71043.1 - 0.0012 18.3 2.0 3.9 7.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMR71043.1 - 0.031 14.4 0.2 4.4 7.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMR71043.1 - 0.037 14.4 0.0 0.037 14.4 0.0 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EMR71043.1 - 0.042 13.6 0.9 22 5.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EMR71043.1 - 0.16 11.9 0.6 37 4.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MscS_porin PF12795.2 EMR71043.1 - 0.21 10.8 2.1 0.41 9.9 1.5 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain SCP2 PF02036.12 EMR71044.1 - 7e-25 87.2 0.4 8.1e-25 87.0 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EMR71044.1 - 7.1e-05 22.7 0.2 9e-05 22.4 0.2 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Mito_carr PF00153.22 EMR71045.1 - 2.6e-55 184.1 0.1 1.6e-18 66.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2_4 PF13894.1 EMR71046.1 - 0.00081 19.5 17.0 1.1 9.7 2.3 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMR71046.1 - 0.0028 17.7 9.4 0.035 14.2 0.1 3.7 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EMR71046.1 - 0.0037 17.4 3.6 3.5 7.9 0.0 3.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EMR71046.1 - 0.011 16.0 15.6 0.59 10.5 0.1 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-TRAF PF02176.13 EMR71046.1 - 1.1 9.6 7.2 0.23 11.8 1.0 2.6 2 0 0 2 2 2 0 TRAF-type zinc finger GAF_2 PF13185.1 EMR71047.1 - 1e-05 26.0 0.0 1.4e-05 25.6 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EMR71047.1 - 0.0012 18.9 0.0 0.0014 18.7 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 EMR71047.1 - 0.0096 16.0 0.0 0.019 15.1 0.0 1.4 1 1 0 1 1 1 1 GAF domain S_layer_N PF05123.7 EMR71047.1 - 0.12 11.9 2.0 0.17 11.4 1.1 1.4 1 1 0 1 1 1 0 S-layer like family, N-terminal region AlaDh_PNT_C PF01262.16 EMR71047.1 - 0.24 10.9 1.1 0.37 10.3 0.2 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_76 PF03663.9 EMR71050.1 - 1.3e-17 64.2 10.8 1.4e-09 37.8 0.1 4.7 5 0 0 5 5 5 3 Glycosyl hydrolase family 76 tRNA-synt_2 PF00152.15 EMR71051.1 - 9.7e-79 264.5 0.0 1.1e-78 264.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EMR71051.1 - 7.1e-07 28.6 0.0 0.00048 19.4 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EMR71051.1 - 3.1e-05 23.7 0.0 5.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EMR71051.1 - 0.0026 17.3 0.0 0.67 9.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) ADK PF00406.17 EMR71054.1 - 5.2e-34 117.2 0.0 2.6e-19 69.5 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EMR71054.1 - 4.2e-13 48.7 0.0 7e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EMR71054.1 - 1.5e-05 25.3 0.0 0.0087 16.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EMR71054.1 - 0.0011 19.8 0.0 0.0046 17.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMR71054.1 - 0.0069 16.2 0.0 0.049 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EMR71054.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF4357 PF14267.1 EMR71054.1 - 0.34 10.5 1.9 0.79 9.3 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) zf-Tim10_DDP PF02953.10 EMR71055.1 - 9.1e-23 79.3 2.1 1e-22 79.1 1.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EMR71055.1 - 0.00087 18.7 1.7 0.00098 18.5 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) BrkDBD PF09607.5 EMR71055.1 - 0.038 13.5 0.0 0.31 10.6 0.0 2.1 2 1 0 2 2 2 0 Brinker DNA-binding domain COesterase PF00135.23 EMR71056.1 - 1.1e-76 258.7 3.1 3.3e-73 247.2 2.1 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR71056.1 - 0.00023 20.8 3.0 0.0021 17.7 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold ER_lumen_recept PF00810.13 EMR71059.1 - 2.8e-36 125.2 8.4 5.1e-36 124.3 5.8 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF1516 PF07457.6 EMR71059.1 - 0.016 15.2 1.0 0.032 14.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) PQ-loop PF04193.9 EMR71059.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.8 4 0 0 4 4 4 0 PQ loop repeat CDC45 PF02724.9 EMR71059.1 - 0.48 8.4 4.6 0.58 8.1 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EMR71059.1 - 0.71 7.7 13.6 0.86 7.4 9.5 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EMR71059.1 - 9 5.4 14.0 13 4.8 9.7 1.2 1 0 0 1 1 1 0 NOA36 protein WSC PF01822.14 EMR71060.1 - 1.3e-12 47.4 9.6 3.3e-12 46.1 6.6 1.7 1 0 0 1 1 1 1 WSC domain Abhydrolase_5 PF12695.2 EMR71060.1 - 4.4e-06 26.5 0.4 1.3e-05 24.9 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EMR71060.1 - 0.0089 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EMR71060.1 - 0.018 14.6 0.0 0.071 12.6 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_6 PF12697.2 EMR71060.1 - 0.019 14.8 0.2 0.063 13.1 0.1 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EMR71060.1 - 0.033 13.5 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.11 EMR71060.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Porin_1 PF00267.16 EMR71061.1 - 0.022 14.0 0.0 0.031 13.5 0.0 1.1 1 0 0 1 1 1 0 Gram-negative porin DBP10CT PF08147.7 EMR71063.1 - 2.5e-18 65.6 1.6 7.2e-17 60.9 1.1 2.6 1 1 0 1 1 1 1 DBP10CT (NUC160) domain DNA_mis_repair PF01119.14 EMR71064.1 - 3.5e-34 116.8 0.1 7.8e-34 115.6 0.0 1.6 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain PC_rep PF01851.17 EMR71065.1 - 2.4e-21 74.6 16.6 3.3e-06 27.0 0.0 9.0 9 0 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EMR71065.1 - 3e-09 37.0 0.9 0.00022 21.4 0.1 4.0 3 2 2 5 5 5 3 HEAT repeats TPR_5 PF12688.2 EMR71065.1 - 0.068 13.2 0.5 6.1 6.9 0.0 3.2 2 1 1 3 3 3 0 Tetratrico peptide repeat NuA4 PF09340.5 EMR71067.1 - 1.7e-21 75.6 0.2 3.2e-21 74.7 0.1 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 RRM_6 PF14259.1 EMR71068.1 - 2.2e-05 24.3 0.2 5.8e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR71068.1 - 3.8e-05 23.4 0.2 8.5e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR71068.1 - 0.00014 21.4 0.4 0.00047 19.7 0.3 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FBPase PF00316.15 EMR71069.1 - 7.3e-52 176.1 0.0 1.2e-51 175.5 0.0 1.3 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EMR71069.1 - 0.034 13.4 0.6 0.091 12.0 0.1 1.8 2 0 0 2 2 2 0 Inositol monophosphatase family IMD PF08397.6 EMR71070.1 - 8e-05 22.0 0.3 0.2 10.9 0.0 2.1 2 0 0 2 2 2 2 IRSp53/MIM homology domain DUF1687 PF07955.6 EMR71071.1 - 1.7e-19 70.1 1.6 8.4e-19 67.8 1.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 EMR71071.1 - 0.072 13.1 0.0 0.87 9.6 0.0 2.3 1 1 0 1 1 1 0 ArsC family DUF1390 PF07150.6 EMR71071.1 - 0.17 11.2 1.5 0.21 10.9 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) Zn_clus PF00172.13 EMR71073.1 - 1.8e-05 24.5 11.5 3e-05 23.8 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2338 PF10100.4 EMR71073.1 - 0.062 11.6 0.0 0.091 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) Clusterin PF01093.12 EMR71073.1 - 3.9 6.1 5.6 6.7 5.4 3.9 1.3 1 0 0 1 1 1 0 Clusterin L51_S25_CI-B8 PF05047.11 EMR71074.1 - 2.3e-13 49.6 0.0 3e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ABC2_membrane PF01061.19 EMR71075.1 - 1.2e-78 263.1 43.5 1.3e-45 155.1 12.9 3.3 4 1 0 4 4 2 2 ABC-2 type transporter ABC_tran PF00005.22 EMR71075.1 - 7.2e-40 136.4 0.0 7.6e-20 71.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EMR71075.1 - 1.1e-29 102.1 0.0 2.2e-24 85.0 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EMR71075.1 - 6.9e-08 32.4 0.0 1.5e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EMR71075.1 - 1.3e-05 24.7 0.0 0.012 15.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EMR71075.1 - 1.3e-05 24.4 31.8 0.0026 16.8 12.4 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 EMR71075.1 - 0.00011 22.2 0.3 0.064 13.2 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMR71075.1 - 0.00045 20.3 0.1 0.15 12.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMR71075.1 - 0.00055 19.1 0.1 0.0044 16.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 EMR71075.1 - 0.0011 18.5 0.8 0.37 10.2 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EMR71075.1 - 0.0011 18.4 0.5 0.076 12.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EMR71075.1 - 0.0017 18.6 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EMR71075.1 - 0.0018 18.1 0.2 0.47 10.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EMR71075.1 - 0.0092 15.9 2.9 0.38 10.7 0.4 2.7 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EMR71075.1 - 0.02 15.7 0.0 1.1 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EMR71075.1 - 0.021 14.0 0.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.4 EMR71075.1 - 0.025 14.0 0.1 1.6 8.1 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 EMR71075.1 - 0.026 14.2 1.6 4.4 7.1 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_21 PF13304.1 EMR71075.1 - 0.027 14.4 0.0 2.3 8.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EMR71075.1 - 0.04 13.6 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 EMR71075.1 - 0.042 13.4 0.6 3.8 7.1 0.3 2.4 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 EMR71075.1 - 0.068 13.3 0.0 20 5.3 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EMR71075.1 - 0.14 12.6 0.0 5.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Ank_2 PF12796.2 EMR71076.1 - 2.9e-14 53.1 0.0 8.9e-06 25.9 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMR71076.1 - 1.2e-09 37.4 0.0 0.074 12.8 0.0 5.7 6 1 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 EMR71076.1 - 3.1e-09 36.1 0.3 0.27 11.6 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.1 EMR71076.1 - 1.3e-08 35.1 0.4 0.034 14.6 0.0 5.4 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR71076.1 - 3.9e-05 23.7 2.4 0.48 10.7 0.0 4.4 4 2 1 5 5 5 2 Ankyrin repeats (many copies) PGA_cap PF09587.5 EMR71076.1 - 0.0088 15.4 0.2 0.086 12.1 0.0 2.1 2 0 0 2 2 2 1 Bacterial capsule synthesis protein PGA_cap Ribosomal_60s PF00428.14 EMR71077.1 - 0.026 14.9 4.5 0.061 13.7 1.7 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Seipin PF06775.9 EMR71078.1 - 2.8e-41 141.2 0.0 3.3e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Aminotran_4 PF01063.14 EMR71079.1 - 1.9e-29 102.7 0.0 2.8e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV DUF1411 PF07199.6 EMR71080.1 - 0.014 14.7 1.3 0.057 12.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) Macoilin PF09726.4 EMR71080.1 - 0.82 7.8 6.6 0.33 9.1 1.1 2.0 2 0 0 2 2 2 0 Transmembrane protein SIR2 PF02146.12 EMR71081.1 - 1.2e-56 191.2 0.0 1.8e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EMR71081.1 - 0.0018 17.8 0.0 0.004 16.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EMR71081.1 - 0.088 12.5 0.1 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain BSMAP PF12280.3 EMR71082.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 Brain specific membrane anchored protein Polyketide_cyc2 PF10604.4 EMR71083.1 - 2.1e-09 37.6 0.4 2.5e-09 37.4 0.3 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EMR71083.1 - 0.024 14.6 0.7 0.028 14.3 0.5 1.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport ETF_QO PF05187.8 EMR71084.1 - 3.7e-45 152.4 0.0 6.2e-45 151.7 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EMR71084.1 - 0.024 13.5 0.0 0.041 12.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase zf-primase PF09329.6 EMR71085.1 - 2.9e-17 61.9 0.9 5.2e-17 61.1 0.6 1.4 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.5 EMR71086.1 - 6.7e-33 114.1 4.5 1e-32 113.5 3.1 1.3 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) SSP160 PF06933.6 EMR71086.1 - 0.00035 18.7 6.7 0.0004 18.5 4.7 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Med3 PF11593.3 EMR71086.1 - 0.099 11.8 9.4 0.11 11.7 6.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal XAP5 PF04921.9 EMR71086.1 - 0.37 10.3 7.7 0.36 10.3 0.1 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator Herpes_capsid PF06112.6 EMR71086.1 - 1.1 9.2 14.1 2.3 8.2 9.7 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Beta-lactamase PF00144.19 EMR71087.1 - 1.2e-49 169.0 2.2 1.8e-49 168.5 1.5 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EMR71087.1 - 0.00025 20.8 0.0 0.00086 19.1 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) FAD_binding_4 PF01565.18 EMR71088.1 - 4.7e-23 81.2 0.2 8.3e-23 80.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR71088.1 - 0.00061 19.6 0.1 0.0019 18.0 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like AdoMet_MTase PF07757.8 EMR71088.1 - 0.11 12.6 0.0 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Pkinase PF00069.20 EMR71089.1 - 2.2e-08 33.5 0.0 5.7e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR71089.1 - 1.4e-07 30.8 0.0 3.8e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3433 PF11915.3 EMR71089.1 - 0.041 14.0 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) Cys_Met_Meta_PP PF01053.15 EMR71090.1 - 2.5e-28 98.4 0.0 4.7e-28 97.5 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EMR71090.1 - 0.039 12.8 0.0 0.057 12.3 0.0 1.3 1 1 0 1 1 1 0 Aminotransferase class I and II PDE6_gamma PF04868.7 EMR71090.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit Polysacc_lyase PF14099.1 EMR71091.1 - 0.0015 18.2 2.1 0.0046 16.6 1.5 1.8 1 1 0 1 1 1 1 Polysaccharide lyase TTL PF03133.10 EMR71092.1 - 3.6e-58 196.8 0.0 5.3e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EMR71092.1 - 3.5e-41 140.7 0.0 5.2e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 EMR71092.1 - 0.00078 19.2 0.1 0.05 13.3 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 EMR71092.1 - 0.0039 16.0 0.0 0.03 13.1 0.0 2.2 3 0 0 3 3 3 1 YheC/D like ATP-grasp Glyco_trans_4_4 PF13579.1 EMR71092.1 - 0.011 15.8 0.3 0.027 14.6 0.2 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_transf_28 PF03033.15 EMR71092.1 - 0.021 14.5 0.0 0.072 12.8 0.0 2.0 2 1 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain Nro1 PF12753.2 EMR71092.1 - 0.96 8.3 3.7 1.6 7.5 2.5 1.3 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 E1-E2_ATPase PF00122.15 EMR71093.1 - 1.5e-54 184.4 0.5 1.5e-54 184.4 0.4 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMR71093.1 - 7.4e-40 136.4 7.1 7.4e-40 136.4 4.9 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMR71093.1 - 5.7e-29 102.0 0.0 6.3e-28 98.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMR71093.1 - 3.2e-20 71.8 0.0 7e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMR71093.1 - 7.1e-17 62.2 0.0 1.6e-16 61.0 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMR71093.1 - 4.3e-06 26.0 0.0 1.5e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMR71093.1 - 5.3e-06 26.1 0.4 0.0001 22.0 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2976 PF11190.3 EMR71093.1 - 0.11 12.0 9.6 0.22 11.0 0.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) FCH PF00611.18 EMR71094.1 - 4.3e-21 74.9 0.0 4.3e-21 74.9 0.0 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EMR71094.1 - 1.7e-12 46.5 0.0 3.9e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMR71094.1 - 4.5e-11 42.0 0.0 5.8e-10 38.5 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EMR71094.1 - 1.2e-10 40.7 0.0 2.5e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PAT1 PF09770.4 EMR71094.1 - 6.6 4.8 36.0 15 3.7 24.9 1.6 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ESSS PF10183.4 EMR71096.1 - 7.1e-29 100.3 0.2 8.7e-29 100.0 0.1 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ATP-synt_E PF05680.7 EMR71096.1 - 0.036 14.0 0.0 0.089 12.7 0.0 1.6 2 0 0 2 2 2 0 ATP synthase E chain DASH_Duo1 PF08651.5 EMR71097.1 - 1.5e-19 69.3 4.0 2.7e-17 62.1 2.8 2.4 1 1 0 1 1 1 1 DASH complex subunit Duo1 DUF755 PF05501.6 EMR71097.1 - 0.046 13.7 3.6 0.049 13.6 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Remorin_C PF03763.8 EMR71097.1 - 0.089 12.3 8.2 0.16 11.5 5.7 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region SPX PF03105.14 EMR71097.1 - 0.13 12.0 3.3 0.17 11.6 2.3 1.2 1 0 0 1 1 1 0 SPX domain BRF1 PF07741.8 EMR71097.1 - 0.19 11.9 6.9 0.18 12.0 2.3 2.0 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF1764 PF08576.5 EMR71097.1 - 3.1 8.6 8.7 5 7.9 2.2 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF3445 PF11927.3 EMR71098.1 - 3.5e-73 246.0 0.0 4.3e-73 245.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Bac_rhamnosid_N PF08531.5 EMR71098.1 - 0.031 13.7 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain AMP-binding PF00501.23 EMR71099.1 - 1.1e-79 267.8 0.0 2.6e-79 266.5 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EMR71099.1 - 1.3e-61 207.7 0.0 1.8e-60 203.9 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EMR71099.1 - 1.6e-34 119.2 10.0 1.5e-32 112.8 4.3 2.8 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EMR71099.1 - 2.8e-18 66.5 0.5 6.3e-18 65.4 0.3 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR71099.1 - 4.7e-17 62.2 7.3 4.2e-15 55.8 3.1 2.5 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 EMR71099.1 - 1.1e-16 61.0 0.4 3e-09 36.6 0.0 2.9 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EMR71099.1 - 1.7e-09 38.4 0.4 3.6e-08 34.2 0.2 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 EMR71099.1 - 1e-08 34.4 1.2 0.0024 16.8 0.2 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EMR71099.1 - 1.2e-08 34.0 0.1 1.2e-05 24.1 0.0 2.8 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMR71099.1 - 1.9e-08 34.5 1.7 0.00015 21.8 1.2 3.6 2 2 0 2 2 2 2 NADH(P)-binding PP-binding PF00550.20 EMR71099.1 - 4e-08 33.4 0.0 1.2e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EMR71099.1 - 1.8e-06 27.1 1.1 0.0015 17.5 0.0 3.5 2 1 0 2 2 2 2 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EMR71099.1 - 0.0057 16.4 1.1 0.017 14.8 0.8 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EMR71099.1 - 0.017 14.1 0.1 0.045 12.8 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 EMR71099.1 - 0.06 12.9 1.2 0.13 11.8 0.8 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ApbA PF02558.11 EMR71099.1 - 0.081 12.3 0.1 0.2 11.0 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.8 EMR71099.1 - 0.33 10.1 2.7 15 4.7 1.1 3.0 3 0 0 3 3 3 0 NmrA-like family DUF3210 PF11489.3 EMR71100.1 - 1.4e-200 668.6 79.2 1.4e-200 668.6 54.9 2.6 1 1 2 3 3 3 2 Protein of unknown function (DUF3210) Rdx PF10262.4 EMR71101.1 - 3.1e-28 97.6 0.0 7.5e-28 96.3 0.0 1.7 1 1 0 1 1 1 1 Rdx family DUF3446 PF11928.3 EMR71101.1 - 0.0099 16.0 1.4 0.0099 16.0 1.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3446) Ten_N PF06484.7 EMR71101.1 - 0.79 8.7 4.9 0.86 8.6 0.2 2.4 3 0 0 3 3 3 0 Teneurin Intracellular Region DUF1206 PF06724.6 EMR71101.1 - 6.1 6.6 7.3 9.4 6.0 2.7 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) NACHT PF05729.7 EMR71102.1 - 8.3e-08 32.0 0.0 2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.2 EMR71102.1 - 9.7e-06 25.8 0.0 3.6e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) AAA_22 PF13401.1 EMR71102.1 - 0.00013 22.1 0.0 0.00049 20.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Ank PF00023.25 EMR71102.1 - 0.00027 20.6 0.0 2 8.3 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeat AAA_16 PF13191.1 EMR71102.1 - 0.0013 18.8 0.1 0.017 15.1 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.1 EMR71102.1 - 0.031 14.5 0.0 3.4 8.1 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat RNA_helicase PF00910.17 EMR71102.1 - 0.15 12.2 0.0 0.54 10.4 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Metallophos PF00149.23 EMR71103.1 - 6.7e-45 152.9 0.2 8.1e-45 152.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 EMR71104.1 - 5.6e-05 22.1 0.0 7.4e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF605 PF04652.11 EMR71104.1 - 1.8 7.9 6.5 2.3 7.5 4.5 1.1 1 0 0 1 1 1 0 Vta1 like VHS PF00790.14 EMR71105.1 - 1.9e-36 124.8 0.1 4.8e-36 123.4 0.1 1.7 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 EMR71105.1 - 9.5e-17 60.3 0.2 1.8e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMR71105.1 - 1.2e-16 59.8 0.4 2.3e-16 58.8 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EMR71105.1 - 1e-13 50.5 0.0 2.2e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 EMR71105.1 - 0.0099 15.3 4.0 0.023 14.2 2.8 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF1237 PF06824.6 EMR71106.1 - 5e-171 568.9 0.0 5.8e-171 568.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) DASH_Dam1 PF08653.5 EMR71106.1 - 0.081 12.6 0.1 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 DASH complex subunit Dam1 FAD_binding_3 PF01494.14 EMR71107.1 - 4e-27 95.1 0.0 4.5e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EMR71107.1 - 1.5e-05 23.7 0.0 2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EMR71107.1 - 9.9e-05 22.2 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EMR71107.1 - 0.00012 21.2 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EMR71107.1 - 0.00052 19.0 0.1 0.048 12.5 0.1 2.2 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR71107.1 - 0.0015 18.6 0.0 0.0071 16.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR71107.1 - 0.003 16.5 0.1 0.008 15.1 0.1 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EMR71107.1 - 0.0099 14.7 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EMR71107.1 - 0.021 15.2 0.0 0.08 13.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR71107.1 - 0.12 12.1 0.1 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glyco_hydro_18 PF00704.23 EMR71109.1 - 1.1e-57 196.0 0.8 1.5e-57 195.5 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EMR71109.1 - 1.1e-07 31.7 26.5 9.3e-06 25.5 8.1 2.8 2 0 0 2 2 2 2 Chitin recognition protein Cadherin-like PF12733.2 EMR71109.1 - 0.13 12.6 1.2 0.74 10.1 0.4 2.5 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain EphA2_TM PF14575.1 EMR71111.1 - 0.074 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glyco_hydro_43 PF04616.9 EMR71112.1 - 1.8e-25 89.6 0.1 9e-24 84.0 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Esterase_phd PF10503.4 EMR71113.1 - 1.4e-18 67.0 0.3 2.1e-18 66.4 0.2 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EMR71113.1 - 7.3e-11 41.6 0.2 9.8e-11 41.2 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EMR71113.1 - 2.9e-05 23.8 0.1 3.7e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR71113.1 - 0.00018 21.4 0.1 0.00034 20.5 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR71113.1 - 0.0019 17.8 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EMR71113.1 - 0.012 15.0 0.1 0.012 15.0 0.1 1.8 2 0 0 2 2 2 0 Putative esterase COesterase PF00135.23 EMR71113.1 - 0.087 11.5 0.0 0.14 10.8 0.0 1.4 1 1 0 1 1 1 0 Carboxylesterase family adh_short PF00106.20 EMR71114.1 - 1.2e-09 38.3 0.1 2.1e-09 37.5 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMR71114.1 - 0.00052 20.0 0.1 0.00092 19.2 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR71114.1 - 0.037 13.4 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 EMR71114.1 - 0.038 13.6 0.1 0.1 12.2 0.1 1.8 1 1 0 1 1 1 0 KR domain GMC_oxred_N PF00732.14 EMR71115.1 - 6.2e-51 173.2 0.0 8.4e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR71115.1 - 1.3e-38 132.5 0.0 2.3e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EMR71115.1 - 7.9e-06 25.0 0.7 3e-05 23.1 0.4 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR71115.1 - 2.4e-05 23.3 0.1 0.00042 19.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EMR71115.1 - 8.6e-05 22.4 0.0 0.00024 21.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EMR71115.1 - 0.00049 19.1 0.1 0.00071 18.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EMR71115.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EMR71115.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR71115.1 - 0.056 13.5 0.0 0.19 11.8 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR71115.1 - 0.15 10.4 0.1 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ArgJ PF01960.13 EMR71115.1 - 0.19 10.1 0.0 0.27 9.5 0.0 1.1 1 0 0 1 1 1 0 ArgJ family DKCLD PF08068.7 EMR71116.1 - 4.9e-28 96.8 0.2 2.8e-27 94.4 0.1 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EMR71116.1 - 1.6e-24 86.7 0.1 1.2e-21 77.4 0.1 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EMR71116.1 - 6.8e-21 73.7 1.4 1.3e-20 72.8 1.0 1.5 1 0 0 1 1 1 1 PUA domain Med19 PF10278.4 EMR71116.1 - 1.4 8.5 9.1 2.7 7.6 6.3 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_M43 PF05572.8 EMR71117.1 - 7.3e-16 58.1 0.1 1.6e-15 56.9 0.0 1.7 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EMR71117.1 - 1.8e-05 24.8 0.1 3.5e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMR71117.1 - 0.0014 19.1 1.5 0.0026 18.3 1.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EMR71117.1 - 0.0044 16.5 0.9 0.0088 15.5 0.6 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMR71117.1 - 0.024 14.6 10.0 0.06 13.4 6.9 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EMR71117.1 - 0.23 11.1 1.7 0.42 10.3 1.2 1.6 1 1 0 1 1 1 0 Matrixin adh_short PF00106.20 EMR71118.1 - 6.8e-19 68.3 2.3 1.2e-18 67.5 1.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR71118.1 - 1.2e-11 44.6 0.9 1.9e-11 43.9 0.6 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR71118.1 - 8.4e-05 22.4 0.1 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EMR71118.1 - 0.042 13.6 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DAG1 PF05454.6 EMR71119.1 - 0.00019 20.7 0.0 0.00035 19.8 0.0 1.4 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Podoplanin PF05808.6 EMR71119.1 - 0.00043 19.8 0.1 0.0011 18.4 0.0 1.7 1 0 0 1 1 1 1 Podoplanin IncA PF04156.9 EMR71119.1 - 0.0019 17.8 0.1 0.0038 16.8 0.1 1.4 1 0 0 1 1 1 1 IncA protein CD34_antigen PF06365.7 EMR71119.1 - 0.0021 17.7 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family Shisa PF13908.1 EMR71119.1 - 0.0048 17.0 0.0 0.0048 17.0 0.0 2.6 2 1 0 2 2 2 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 EMR71119.1 - 0.0093 14.2 0.0 0.017 13.3 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 EMR71119.1 - 0.015 14.8 7.3 0.029 13.9 5.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM154 PF15102.1 EMR71119.1 - 0.016 14.9 0.1 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family DAP10 PF07213.6 EMR71119.1 - 0.024 14.3 0.1 0.071 12.8 0.1 1.7 1 0 0 1 1 1 0 DAP10 membrane protein DUF4448 PF14610.1 EMR71119.1 - 0.028 13.9 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.5 EMR71119.1 - 0.046 13.0 1.3 0.11 11.8 0.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EMR71119.1 - 0.058 13.8 0.2 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Yip1 PF04893.12 EMR71119.1 - 0.08 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain PepSY_TM_2 PF13703.1 EMR71119.1 - 0.12 12.5 0.0 0.36 11.0 0.0 1.7 2 0 0 2 2 1 0 PepSY-associated TM helix PsbX PF06596.6 EMR71119.1 - 4.6 6.9 6.0 9.1 6.0 4.2 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Peptidase_S8 PF00082.17 EMR71120.1 - 8.8e-10 38.1 1.1 9.7e-10 38.0 0.0 1.5 2 0 0 2 2 2 1 Subtilase family CBF PF03914.12 EMR71121.1 - 4e-46 156.4 0.7 7.9e-46 155.5 0.1 1.7 2 0 0 2 2 2 1 CBF/Mak21 family Mt_ATP-synt_B PF05405.9 EMR71122.1 - 2e-53 180.1 7.4 2.4e-53 179.9 5.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Rep_trans PF02486.14 EMR71122.1 - 0.045 13.2 0.5 0.077 12.4 0.3 1.4 1 0 0 1 1 1 0 Replication initiation factor rve_3 PF13683.1 EMR71122.1 - 0.079 12.4 0.4 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain Dak2 PF02734.12 EMR71122.1 - 0.089 12.4 2.5 1.5 8.4 1.7 2.2 1 1 0 1 1 1 0 DAK2 domain DUF4071 PF13281.1 EMR71122.1 - 0.12 11.2 4.1 0.16 10.7 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) adh_short PF00106.20 EMR71123.1 - 3.1e-31 108.5 0.5 4.1e-31 108.1 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR71123.1 - 2.1e-19 70.2 0.0 2.7e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR71123.1 - 1.3e-14 54.2 0.2 2e-14 53.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR71123.1 - 2.9e-05 23.6 0.0 5.1e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.6 EMR71123.1 - 0.0059 16.1 0.0 0.16 11.4 0.0 2.3 3 0 0 3 3 3 1 Starch synthase catalytic domain Toprim_3 PF13362.1 EMR71123.1 - 0.011 15.9 0.2 0.72 10.1 0.0 2.5 2 1 0 2 2 2 0 Toprim domain Eno-Rase_NADH_b PF12242.3 EMR71123.1 - 0.035 13.8 0.1 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EMR71123.1 - 0.062 13.3 0.5 0.23 11.4 0.2 2.0 2 1 0 2 2 2 0 NADH(P)-binding ADH_zinc_N PF00107.21 EMR71123.1 - 0.063 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMR71123.1 - 0.095 11.8 0.1 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mito_carr PF00153.22 EMR71124.1 - 0.00043 19.9 0.2 0.0071 16.0 0.0 2.4 2 0 0 2 2 2 1 Mitochondrial carrier protein Attacin_N PF03768.10 EMR71124.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Attacin, N-terminal region MR_MLE_C PF13378.1 EMR71125.1 - 7e-33 112.9 0.1 4.1e-31 107.2 0.0 2.6 2 1 1 3 3 3 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EMR71125.1 - 9.1e-20 70.8 0.0 1.7e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EMR71125.1 - 8.5e-08 32.6 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain NmrA PF05368.8 EMR71126.1 - 4.2e-14 52.3 0.0 5.5e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR71126.1 - 3.8e-10 40.0 0.0 6.9e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Isochorismatase PF00857.15 EMR71127.1 - 2.4e-20 73.1 0.1 2.5e-19 69.8 0.0 2.4 1 1 0 1 1 1 1 Isochorismatase family ADH_N PF08240.7 EMR71128.1 - 1.7e-24 85.6 0.2 3.4e-24 84.6 0.1 1.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR71128.1 - 2e-13 50.0 0.1 4.2e-13 48.9 0.1 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 EMR71128.1 - 0.00078 19.2 0.1 0.0016 18.2 0.1 1.4 1 0 0 1 1 1 1 ThiF family ApbA PF02558.11 EMR71128.1 - 0.023 14.1 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 EMR71128.1 - 0.1 12.6 0.1 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EMR71128.1 - 0.12 12.4 1.7 0.29 11.2 0.5 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Radical_SAM PF04055.16 EMR71129.1 - 4.4e-13 49.7 0.0 8.7e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily DJ-1_PfpI PF01965.19 EMR71131.1 - 1.7e-23 82.7 0.0 6.2e-23 80.8 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EMR71131.1 - 2.7e-12 46.0 0.2 5.4e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family adh_short PF00106.20 EMR71132.1 - 4.8e-23 81.9 0.0 1.8e-22 80.0 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR71132.1 - 4.4e-09 36.4 0.0 5.6e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR71132.1 - 2.4e-07 30.6 0.1 9e-06 25.4 0.1 2.8 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EMR71132.1 - 5e-05 23.3 0.3 0.00013 22.0 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EMR71132.1 - 0.013 14.9 0.0 0.059 12.7 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EMR71132.1 - 0.029 14.4 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EMR71132.1 - 0.043 12.8 0.2 0.06 12.3 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Pkinase PF00069.20 EMR71133.1 - 0.00041 19.5 0.0 0.071 12.2 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EMR71133.1 - 0.024 13.6 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Peptidase_M36 PF02128.10 EMR71134.1 - 2.7e-158 526.7 11.1 3.1e-158 526.5 7.7 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.10 EMR71134.1 - 0.00045 20.0 0.1 0.0011 18.7 0.0 1.6 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_MA_2 PF13485.1 EMR71134.1 - 0.012 15.6 2.2 0.015 15.3 0.1 2.0 2 0 0 2 2 2 0 Peptidase MA superfamily Sugar_tr PF00083.19 EMR71135.1 - 6.6e-19 67.8 16.1 1.2e-09 37.2 7.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR71135.1 - 4.3e-15 55.2 11.2 1.3e-07 30.6 3.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.1 EMR71135.1 - 0.0036 16.7 8.6 0.098 12.0 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4131) IncA PF04156.9 EMR71135.1 - 0.18 11.3 0.6 19 4.7 0.0 2.3 2 0 0 2 2 2 0 IncA protein Prp31_C PF09785.4 EMR71136.1 - 5.5e-45 152.7 1.3 5.5e-45 152.7 0.9 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 EMR71136.1 - 1.9e-39 134.3 0.1 3.1e-39 133.6 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EMR71136.1 - 1e-19 70.0 1.0 2.2e-19 69.0 0.1 2.0 2 0 0 2 2 2 1 NOSIC (NUC001) domain Ligase_CoA PF00549.14 EMR71138.1 - 1.3e-24 86.5 1.1 2.4e-11 43.4 0.0 2.4 2 1 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 EMR71138.1 - 0.0042 17.5 0.7 0.022 15.2 0.3 2.4 2 0 0 2 2 2 1 CoA binding domain Peripla_BP_3 PF13377.1 EMR71138.1 - 0.13 12.2 0.5 6.1 6.8 0.0 2.9 2 1 1 3 3 3 0 Periplasmic binding protein-like domain Rad60-SLD PF11976.3 EMR71139.1 - 3.9e-19 68.0 0.1 4.9e-19 67.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EMR71139.1 - 8.4e-09 34.7 0.0 1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 EMR71139.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) MbeB_N PF04837.7 EMR71140.1 - 0.053 13.6 0.1 0.083 12.9 0.1 1.3 1 0 0 1 1 1 0 MbeB-like, N-term conserved region DUF4544 PF15077.1 EMR71141.1 - 9.5 5.6 8.3 8.4 5.8 4.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4544) TPR_14 PF13428.1 EMR71142.1 - 7.5e-22 75.8 13.6 0.0052 17.3 0.1 9.9 7 2 4 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EMR71142.1 - 4.6e-20 71.7 0.3 2e-05 24.8 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat HAT PF02184.11 EMR71142.1 - 5.1e-19 67.7 74.9 7e-15 54.4 1.2 12.2 15 0 0 15 15 13 5 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 EMR71142.1 - 3.3e-17 62.6 10.3 0.012 16.3 0.1 8.2 9 0 0 9 9 8 4 Tetratricopeptide repeat Suf PF05843.9 EMR71142.1 - 4.6e-16 59.3 13.0 0.00077 19.2 0.5 5.8 3 2 1 6 6 6 4 Suppressor of forked protein (Suf) TPR_15 PF13429.1 EMR71142.1 - 9.8e-11 41.2 14.3 0.00023 20.3 1.7 5.5 2 1 2 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EMR71142.1 - 7.4e-07 28.6 12.4 1.2 9.1 0.0 7.6 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EMR71142.1 - 8.5e-07 28.7 0.2 0.054 13.7 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EMR71142.1 - 1.3e-06 27.9 5.8 0.16 11.6 0.0 5.8 5 1 2 7 7 7 1 TPR repeat TPR_12 PF13424.1 EMR71142.1 - 7.4e-05 22.6 14.7 5.6 6.9 0.0 7.7 7 2 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMR71142.1 - 0.0014 18.9 13.9 53 4.5 0.0 8.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 EMR71142.1 - 0.0034 17.0 10.2 23 5.0 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EMR71142.1 - 0.0075 15.9 26.9 0.089 12.5 0.7 7.4 5 2 4 9 9 8 1 U3 small nucleolar RNA-associated protein 6 TPR_8 PF13181.1 EMR71142.1 - 0.0088 15.7 1.3 23 5.0 0.2 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EMR71142.1 - 0.019 14.7 1.8 2.3 8.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EMR71142.1 - 0.58 10.0 6.6 12 5.8 0.2 4.5 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 EMR71142.1 - 2.2 8.0 5.3 48 3.8 0.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.5 EMR71142.1 - 2.9 8.0 8.1 7.9 6.6 0.0 4.3 4 0 0 4 4 4 0 c-SKI Smad4 binding domain LIM PF00412.17 EMR71143.1 - 9.6e-25 86.4 21.9 2.5e-08 33.8 3.1 3.4 3 0 0 3 3 3 3 LIM domain DUF2321 PF10083.4 EMR71143.1 - 9.9 5.6 9.0 0.22 11.0 0.3 2.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Nup84_Nup100 PF04121.8 EMR71144.1 - 2.4e-66 223.8 0.0 4.5e-57 193.2 0.0 3.4 1 1 1 2 2 2 2 Nuclear pore protein 84 / 107 Cucumo_2B PF03263.8 EMR71144.1 - 0.042 14.1 0.7 0.1 12.9 0.5 1.6 1 0 0 1 1 1 0 Cucumovirus protein 2B Mod_r PF07200.8 EMR71145.1 - 8.1e-08 32.3 10.4 5.7e-07 29.5 7.2 1.9 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Acetate_kinase PF00871.12 EMR71147.1 - 3.8e-88 295.6 0.0 4.7e-88 295.3 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family DNA_binding_1 PF01035.15 EMR71147.1 - 0.13 12.0 0.4 3.7 7.3 0.1 2.4 1 1 1 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain HLH PF00010.21 EMR71148.1 - 9.8e-13 47.5 0.0 2.6e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3734 PF12536.3 EMR71148.1 - 0.012 15.7 0.8 0.45 10.6 0.1 2.4 2 0 0 2 2 2 0 Patatin phospholipase MFS_1 PF07690.11 EMR71149.1 - 1.1e-17 63.7 47.4 3.5e-17 62.1 32.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily NPR3 PF03666.8 EMR71150.1 - 6e-132 440.3 0.0 6e-132 440.3 0.0 1.9 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Lipase_GDSL_2 PF13472.1 EMR71151.1 - 1e-09 38.7 0.1 1.3e-09 38.4 0.1 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMR71151.1 - 0.071 12.9 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Amidohydro_1 PF01979.15 EMR71152.1 - 1.3e-42 146.6 0.1 1.6e-42 146.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMR71152.1 - 1.3e-07 31.9 6.4 4.6e-07 30.1 4.5 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EMR71152.1 - 2.9e-05 23.8 0.0 9e-05 22.2 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMR71152.1 - 0.00033 19.9 13.6 0.00043 19.6 4.2 2.3 1 1 1 2 2 2 2 Amidohydrolase family A_deaminase PF00962.17 EMR71152.1 - 0.00074 18.5 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Atrophin-1 PF03154.10 EMR71152.1 - 2.2 6.3 4.5 3.9 5.5 3.1 1.3 1 0 0 1 1 1 0 Atrophin-1 family TPR_11 PF13414.1 EMR71153.1 - 6.9e-17 60.8 5.8 1.4e-14 53.4 1.3 2.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EMR71153.1 - 5.4e-09 35.2 5.2 0.024 14.5 0.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMR71153.1 - 1.2e-08 34.1 0.1 0.075 12.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMR71153.1 - 5e-07 29.4 1.0 0.036 14.2 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMR71153.1 - 1.5e-06 28.7 13.6 0.00028 21.4 5.0 3.5 2 2 1 3 3 2 2 Tetratricopeptide repeat BTAD PF03704.12 EMR71153.1 - 0.0001 22.6 10.2 0.043 14.1 0.0 3.0 2 1 1 3 3 3 2 Bacterial transcriptional activator domain TPR_7 PF13176.1 EMR71153.1 - 0.00063 19.3 0.2 8.7 6.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMR71153.1 - 0.001 19.4 14.1 0.083 13.5 2.1 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat XPC-binding PF09280.6 EMR71153.1 - 0.0011 18.3 2.4 0.0021 17.4 1.0 1.9 2 0 0 2 2 2 1 XPC-binding domain TPR_9 PF13371.1 EMR71153.1 - 0.0027 17.5 0.3 0.0027 17.5 0.2 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR71153.1 - 0.015 15.6 0.4 0.015 15.6 0.3 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMR71153.1 - 0.031 14.2 5.7 0.073 13.0 1.8 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Hamartin PF04388.7 EMR71153.1 - 0.15 10.6 0.5 0.2 10.2 0.3 1.2 1 0 0 1 1 1 0 Hamartin protein EHN PF06441.7 EMR71154.1 - 2.4e-18 66.0 0.0 2.6e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Epoxide hydrolase N terminus FAD_binding_4 PF01565.18 EMR71155.1 - 9.7e-18 63.9 0.3 2.1e-17 62.9 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain STN PF07660.9 EMR71155.1 - 0.017 14.6 0.0 0.041 13.4 0.0 1.7 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain GBP_PSP PF02425.10 EMR71156.1 - 0.15 11.5 1.4 2.8 7.5 0.2 2.5 1 1 1 2 2 2 0 Paralytic/GBP/PSP peptide Peptidase_S55 PF05580.7 EMR71157.1 - 0.011 15.1 0.1 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 SpoIVB peptidase S55 Ribosomal_S8 PF00410.14 EMR71158.1 - 1e-24 86.8 0.1 1.4e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 TruD PF01142.13 EMR71159.1 - 2.3e-47 161.5 0.0 1e-42 146.2 0.0 3.4 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) XPG_I_2 PF12813.2 EMR71159.1 - 0.025 14.0 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 XPG domain containing Ribosomal_L19 PF01245.15 EMR71160.1 - 2.5e-18 65.8 0.0 5e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Ribosomal_L7Ae PF01248.21 EMR71162.1 - 4.4e-29 99.8 1.2 5.6e-29 99.5 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 EMR71162.1 - 0.096 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Helicase_C_3 PF13625.1 EMR71163.1 - 7.6e-27 93.6 0.0 2.2e-25 88.8 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR71163.1 - 3.1e-13 49.9 0.0 6.6e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EMR71163.1 - 1.6e-10 40.2 0.0 2.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMR71163.1 - 1.9e-10 40.4 0.0 5.4e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2704 PF10866.3 EMR71164.1 - 0.064 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) Pyr_redox_2 PF07992.9 EMR71165.1 - 1.3e-16 61.0 3.3 2.7e-15 56.8 2.3 3.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR71165.1 - 5.8e-15 55.4 0.7 7.3e-11 42.3 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR71165.1 - 6.8e-07 28.5 2.0 0.011 14.6 0.0 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EMR71165.1 - 0.00012 21.1 0.7 0.013 14.4 0.1 3.1 4 0 0 4 4 4 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMR71165.1 - 0.00014 22.0 0.2 0.18 11.8 0.1 3.2 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMR71165.1 - 0.00027 19.6 1.4 2.1 6.8 0.1 3.1 2 1 1 3 3 3 3 Tryptophan halogenase NAD_binding_8 PF13450.1 EMR71165.1 - 0.003 17.5 0.4 0.32 11.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EMR71165.1 - 0.005 15.7 0.0 0.035 13.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EMR71165.1 - 0.019 13.9 0.1 3.8 6.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EMR71165.1 - 0.035 12.9 2.8 3 6.5 0.2 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.12 EMR71165.1 - 0.038 13.0 0.1 0.78 8.7 0.0 2.4 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EMR71165.1 - 0.056 11.8 1.0 0.34 9.3 0.2 2.3 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 EMR71165.1 - 0.24 10.1 3.7 2.9 6.6 0.4 2.8 3 0 0 3 3 3 0 FAD binding domain NAD_binding_9 PF13454.1 EMR71165.1 - 0.41 10.4 2.2 48 3.7 0.0 3.7 3 1 1 4 4 4 0 FAD-NAD(P)-binding adh_short PF00106.20 EMR71167.1 - 3.6e-29 101.8 0.0 5.6e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR71167.1 - 1e-12 48.1 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR71167.1 - 1.9e-12 47.4 0.0 3.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMR71167.1 - 4.8e-06 26.7 0.0 6.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EMR71167.1 - 7.6e-06 25.2 0.0 1e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EMR71167.1 - 2.6e-05 23.7 0.0 6e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EMR71167.1 - 0.00058 19.1 0.1 0.00091 18.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EMR71167.1 - 0.016 15.1 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.12 EMR71167.1 - 0.018 13.9 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 EMR71167.1 - 0.052 12.2 0.1 0.07 11.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PALP PF00291.20 EMR71168.1 - 2.1e-60 204.5 0.9 2.4e-60 204.3 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SAD_SRA PF02182.12 EMR71169.1 - 0.0035 16.6 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain adh_short PF00106.20 EMR71170.1 - 6e-13 49.0 0.0 1.1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR71170.1 - 4.3e-06 26.5 0.0 6.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 KR domain LIM PF00412.17 EMR71171.1 - 0.38 10.8 11.7 0.42 10.7 2.8 3.1 3 0 0 3 3 3 0 LIM domain TrkH PF02386.11 EMR71172.1 - 4e-71 239.4 9.0 3.2e-69 233.2 1.1 2.1 2 0 0 2 2 2 2 Cation transport protein UIM PF02809.15 EMR71173.1 - 0.015 14.8 1.9 0.015 14.8 1.3 3.6 3 0 0 3 3 3 0 Ubiquitin interaction motif MFS_1 PF07690.11 EMR71174.1 - 4.4e-22 78.2 24.3 4.4e-22 78.2 16.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMR71174.1 - 0.023 14.4 5.4 0.23 11.2 0.4 2.6 2 0 0 2 2 2 0 MFS_1 like family DUF3270 PF11674.3 EMR71174.1 - 4.5 7.3 7.0 0.38 10.7 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) RRM_1 PF00076.17 EMR71175.1 - 9.2e-31 105.2 0.1 3.1e-14 52.3 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR71175.1 - 5.8e-24 83.8 0.0 6.8e-12 45.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR71175.1 - 1.2e-08 34.6 0.0 0.002 17.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 EMR71175.1 - 0.018 14.7 0.2 9 6.0 0.0 3.1 3 0 0 3 3 3 0 DbpA RNA binding domain Limkain-b1 PF11608.3 EMR71175.1 - 0.044 13.5 0.0 14 5.4 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 API5 PF05918.6 EMR71175.1 - 0.19 10.1 2.3 0.24 9.8 1.6 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Gly-rich_Ago1 PF12764.2 EMR71175.1 - 3.2 8.4 9.0 15 6.3 6.2 2.1 1 0 0 1 1 1 0 Glycine-rich region of argonaut SOG2 PF10428.4 EMR71176.1 - 0.045 12.4 0.5 0.051 12.2 0.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FAD_binding_1 PF00667.15 EMR71177.1 - 7.1e-26 90.9 0.0 1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EMR71177.1 - 2.4e-13 50.5 0.0 4.6e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FF PF01846.14 EMR71177.1 - 0.035 14.0 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 FF domain Cofilin_ADF PF00241.15 EMR71180.1 - 5.3e-27 94.2 0.0 3.9e-14 52.6 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein PBP PF01161.15 EMR71182.1 - 1.2e-21 77.0 0.0 1.8e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein zf-RING_2 PF13639.1 EMR71182.1 - 0.00023 20.9 1.3 0.00023 20.9 0.9 2.8 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMR71182.1 - 0.00098 19.0 1.3 0.00098 19.0 0.9 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR71182.1 - 0.013 15.2 0.9 0.013 15.2 0.6 3.0 2 1 1 3 3 3 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EMR71182.1 - 0.032 13.8 0.6 0.032 13.8 0.4 2.7 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMR71182.1 - 0.067 12.8 13.9 0.045 13.4 1.7 3.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMR71182.1 - 0.46 10.6 3.4 2.7 8.1 0.2 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger LysM PF01476.15 EMR71183.1 - 6.5e-12 45.1 0.0 1.3e-11 44.1 0.0 1.5 2 0 0 2 2 2 1 LysM domain DUF903 PF06004.7 EMR71183.1 - 7.4 6.1 7.1 0.32 10.5 0.5 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) Sugar_tr PF00083.19 EMR71184.1 - 1.3e-88 297.5 23.1 1.5e-88 297.3 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR71184.1 - 5e-40 137.3 25.1 5e-40 137.3 17.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR71184.1 - 0.00021 19.6 0.9 0.00021 19.6 0.7 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EMR71184.1 - 0.0014 18.3 0.2 2.4 7.9 0.0 2.9 2 0 0 2 2 2 2 MFS_1 like family DUF399 PF04187.8 EMR71184.1 - 0.15 11.4 0.5 0.23 10.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF399 Mito_carr PF00153.22 EMR71185.1 - 9.2e-71 233.6 2.9 4.6e-23 80.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TauE PF01925.14 EMR71186.1 - 0.002 17.6 0.1 0.0023 17.4 0.0 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF4131 PF13567.1 EMR71186.1 - 0.037 13.4 0.1 0.041 13.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Claudin_2 PF13903.1 EMR71186.1 - 0.077 12.6 0.4 0.09 12.4 0.3 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4199 PF13858.1 EMR71186.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Mito_carr PF00153.22 EMR71187.1 - 1e-17 63.6 0.0 1.7e-10 40.4 0.0 3.6 4 1 0 4 4 4 2 Mitochondrial carrier protein Methyltransf_23 PF13489.1 EMR71188.1 - 1.4e-12 47.6 0.0 2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR71188.1 - 5e-05 23.7 0.0 0.00021 21.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR71188.1 - 0.0019 18.7 0.2 0.081 13.5 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EMR71188.1 - 0.016 14.8 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EMR71188.1 - 0.023 14.2 0.0 2.1 7.9 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 EMR71188.1 - 0.033 14.5 0.0 0.71 10.2 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMR71188.1 - 0.044 14.2 0.0 0.47 10.9 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain MARVEL PF01284.18 EMR71189.1 - 1.6e-05 24.7 10.5 2.8e-05 23.9 7.2 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF1229 PF06797.6 EMR71189.1 - 0.012 14.4 0.8 0.016 14.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) Zip PF02535.17 EMR71189.1 - 0.076 12.0 0.7 0.1 11.5 0.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_hydro_88 PF07470.8 EMR71190.1 - 4.4e-08 32.5 0.0 1.3e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 AAA_16 PF13191.1 EMR71191.1 - 2.7e-05 24.2 0.7 0.021 14.7 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain Arch_ATPase PF01637.13 EMR71191.1 - 6.4e-05 22.7 1.3 0.00012 21.8 0.3 1.9 2 1 0 2 2 2 1 Archaeal ATPase AAA_25 PF13481.1 EMR71191.1 - 0.0026 17.1 0.0 0.0066 15.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMR71191.1 - 0.0058 16.7 0.1 0.021 14.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EMR71191.1 - 0.019 15.1 0.3 0.18 11.9 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EMR71191.1 - 0.029 13.4 1.1 0.043 12.9 0.1 1.7 2 0 0 2 2 2 0 KaiC DUF815 PF05673.8 EMR71191.1 - 0.053 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Miro PF08477.8 EMR71191.1 - 0.054 14.0 0.7 1.5 9.3 0.0 2.8 3 1 0 3 3 2 0 Miro-like protein MobB PF03205.9 EMR71191.1 - 0.096 12.3 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EMR71191.1 - 0.099 12.3 0.1 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.1 EMR71191.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain TBPIP PF07106.8 EMR71192.1 - 0.19 11.2 1.6 0.53 9.8 0.0 2.4 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) LrgB PF04172.11 EMR71193.1 - 1.2e-20 73.6 7.5 4.9e-14 52.0 0.2 2.0 2 0 0 2 2 2 2 LrgB-like family DUF228 PF02989.9 EMR71193.1 - 0.063 12.8 0.5 0.14 11.6 0.1 1.7 2 0 0 2 2 2 0 Lyme disease proteins of unknown function Peptidase_S8 PF00082.17 EMR71194.1 - 5.8e-37 127.3 3.5 8.3e-37 126.8 2.4 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMR71194.1 - 1.5e-09 38.2 0.0 2.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3818 PF12825.2 EMR71195.1 - 2.2e-29 102.2 0.8 2.4e-18 65.9 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EMR71195.1 - 2.5e-09 36.8 0.0 4.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 PX-associated Rotamase PF00639.16 EMR71196.1 - 1.1e-22 80.6 0.1 2.1e-22 79.6 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EMR71196.1 - 1.9e-18 66.8 0.0 2.3e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EMR71196.1 - 5.3e-08 32.5 1.4 6.1e-08 32.3 0.3 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 EMR71196.1 - 1.5e-06 28.8 0.0 2.6e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain MbtH PF03621.8 EMR71196.1 - 0.074 12.4 0.0 5 6.5 0.0 2.4 2 0 0 2 2 2 0 MbtH-like protein MARVEL PF01284.18 EMR71197.1 - 2.2e-12 46.9 6.6 2.2e-12 46.9 4.5 1.5 1 1 0 1 1 1 1 Membrane-associating domain Glyco_hydro_47 PF01532.15 EMR71198.1 - 3.3e-155 517.1 0.0 3.8e-155 516.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4610 PF15384.1 EMR71198.1 - 0.22 11.0 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4610) WD40 PF00400.27 EMR71199.1 - 6.9e-50 165.2 9.5 8e-10 38.2 0.0 7.3 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EMR71199.1 - 1.7e-12 46.3 1.2 0.012 13.7 0.0 4.1 2 1 1 4 4 4 4 Nucleoporin Nup120/160 F-box-like PF12937.2 EMR71199.1 - 0.00063 19.4 0.2 0.0016 18.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMR71199.1 - 0.0032 17.0 0.1 0.0092 15.6 0.1 1.8 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EMR71199.1 - 0.12 11.1 2.1 3.6 6.2 0.2 2.5 1 1 1 2 2 2 0 Nup133 N terminal like MHC_I_C PF06623.6 EMR71199.1 - 0.46 10.0 4.2 1 8.8 2.9 1.6 1 0 0 1 1 1 0 MHC_I C-terminus AATase PF07247.7 EMR71200.1 - 1.7e-17 63.1 0.0 7.4e-17 61.0 0.0 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EMR71200.1 - 0.00051 18.9 0.2 0.003 16.4 0.1 2.3 1 1 0 1 1 1 1 Condensation domain S10_plectin PF03501.10 EMR71201.1 - 3.6e-41 138.9 0.2 4.3e-41 138.6 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain ADH_N PF08240.7 EMR71202.1 - 6.4e-28 96.6 1.1 1.3e-27 95.6 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR71202.1 - 1.7e-15 56.7 0.0 3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR71202.1 - 6.2e-05 23.8 0.0 0.0001 23.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EMR71202.1 - 7.6e-05 21.9 0.1 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 EMR71202.1 - 0.013 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EMR71202.1 - 0.14 11.9 0.1 0.33 10.7 0.0 1.6 2 0 0 2 2 2 0 ThiF family NADH_4Fe-4S PF10589.4 EMR71202.1 - 5.2 6.3 7.8 0.14 11.3 0.3 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Telomere_Sde2 PF13019.1 EMR71203.1 - 7.2e-68 227.3 0.3 1e-67 226.8 0.2 1.2 1 0 0 1 1 1 1 Telomere stability and silencing DUF4483 PF14825.1 EMR71203.1 - 0.52 9.9 6.6 1.4 8.5 4.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4483) RCR PF12273.3 EMR71204.1 - 0.00012 22.6 4.7 0.00016 22.2 3.2 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Sugar_tr PF00083.19 EMR71205.1 - 1.2e-114 383.3 22.8 1.7e-114 382.8 15.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR71205.1 - 1.9e-29 102.4 41.9 1.3e-26 93.1 19.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Asp PF00026.18 EMR71205.1 - 2.7e-15 56.4 0.0 1.2e-14 54.2 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF1725 PF08333.6 EMR71208.1 - 0.046 13.0 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) zf-Di19 PF05605.7 EMR71209.1 - 0.55 10.3 3.1 0.37 10.9 0.3 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EMR71209.1 - 1.7 9.1 14.8 0.9 10.0 0.1 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger zf-tcix PF14952.1 EMR71209.1 - 3.7 6.9 9.5 0.26 10.6 0.4 3.1 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding AMP-binding PF00501.23 EMR71211.1 - 1.4e-32 112.6 0.1 2.5e-16 59.1 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EMR71211.1 - 3.1e-09 37.6 0.1 5.6e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phosphodiest PF01663.17 EMR71212.1 - 4.1e-18 65.8 1.8 1.4e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMR71212.1 - 0.017 14.3 0.1 0.21 10.7 0.0 2.1 2 0 0 2 2 2 0 Sulfatase Metalloenzyme PF01676.13 EMR71212.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily Pox_A14 PF05767.7 EMR71212.1 - 0.51 10.3 3.3 0.96 9.4 0.6 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Alpha-amylase PF00128.19 EMR71213.1 - 1.5e-53 182.2 1.9 6.8e-52 176.8 1.3 2.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EMR71213.1 - 0.00087 19.3 0.1 0.0024 17.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Cellulase PF00150.13 EMR71213.1 - 0.013 14.6 0.1 0.053 12.7 0.0 2.0 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Aminotran_5 PF00266.14 EMR71213.1 - 0.047 12.4 0.2 0.097 11.3 0.1 1.5 2 0 0 2 2 2 0 Aminotransferase class-V GHL6 PF14871.1 EMR71213.1 - 0.082 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 hDGE_amylase PF14701.1 EMR71213.1 - 0.089 11.6 0.1 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme NHL PF01436.16 EMR71213.1 - 0.27 11.2 2.0 0.58 10.2 0.2 2.4 2 0 0 2 2 2 0 NHL repeat Lipase_GDSL_2 PF13472.1 EMR71214.1 - 7.9e-22 78.2 0.1 9.1e-22 78.0 0.1 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EMR71214.1 - 0.0022 17.7 0.1 0.12 12.1 0.0 2.7 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EMR71214.1 - 0.0025 17.6 0.0 0.026 14.3 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RRM_1 PF00076.17 EMR71215.1 - 1.7e-59 197.3 0.0 1.7e-18 65.9 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR71215.1 - 2.5e-46 155.5 0.0 2e-15 56.5 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR71215.1 - 1.3e-16 60.1 0.0 2.1e-06 27.4 0.0 4.3 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 EMR71215.1 - 0.029 12.4 14.2 0.073 11.0 9.8 1.7 1 0 0 1 1 1 0 CDC45-like protein Adeno_terminal PF02459.10 EMR71215.1 - 0.035 12.2 1.8 0.064 11.4 1.2 1.4 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Nop14 PF04147.7 EMR71215.1 - 0.91 7.3 33.5 0.067 11.1 19.2 2.0 2 0 0 2 2 2 0 Nop14-like family Daxx PF03344.10 EMR71215.1 - 1.4 7.2 32.3 0.17 10.3 19.1 1.8 2 0 0 2 2 2 0 Daxx Family Glyco_transf_22 PF03901.12 EMR71216.1 - 1.2e-42 146.4 14.9 4.2e-33 114.9 6.9 2.1 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family PMT_2 PF13231.1 EMR71216.1 - 0.011 15.5 6.1 0.011 15.5 4.2 1.7 1 1 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase BBE PF08031.7 EMR71217.1 - 0.021 14.7 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 Berberine and berberine like COesterase PF00135.23 EMR71219.1 - 1.4e-98 330.9 0.0 1.6e-98 330.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR71219.1 - 2.2e-05 24.1 1.0 0.00016 21.3 0.1 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_M14 PF00246.19 EMR71220.1 - 3.7e-68 230.1 0.1 4.5e-68 229.8 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Acetyltransf_1 PF00583.19 EMR71222.1 - 2.1e-09 37.2 0.0 3.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMR71222.1 - 4.4e-09 36.4 0.0 5.9e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR71222.1 - 1.1e-08 35.1 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain p450 PF00067.17 EMR71223.1 - 1.1e-27 96.6 0.0 9e-18 64.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 APH PF01636.18 EMR71224.1 - 6e-07 29.4 0.0 3.8e-06 26.8 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EMR71224.1 - 0.00019 20.7 0.0 0.00048 19.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EMR71224.1 - 0.00058 19.4 0.2 0.0012 18.5 0.1 1.5 1 1 1 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 EMR71224.1 - 0.0012 18.2 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 EMR71224.1 - 0.0047 16.0 0.0 0.027 13.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.3 EMR71224.1 - 0.0077 15.6 0.1 0.0091 15.4 0.1 1.1 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 DUF2167 PF09935.4 EMR71224.1 - 0.057 12.2 0.3 0.082 11.7 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2167) Kinase-like PF14531.1 EMR71224.1 - 0.065 12.1 0.0 0.085 11.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like PAT1 PF09770.4 EMR71225.1 - 7.3 4.7 8.5 9.6 4.2 5.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Abhydrolase_6 PF12697.2 EMR71226.1 - 8e-06 25.8 0.1 1.7e-05 24.8 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR71226.1 - 1.9e-05 24.4 0.1 5e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family AA_permease_2 PF13520.1 EMR71227.1 - 1.4e-56 191.8 50.5 1.7e-56 191.5 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMR71227.1 - 7.3e-33 113.6 43.4 9.8e-33 113.1 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease Pyr_redox_2 PF07992.9 EMR71228.1 - 3.6e-18 66.1 0.5 5.1e-18 65.6 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR71228.1 - 4.9e-05 22.3 0.5 0.0023 16.8 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EMR71228.1 - 0.00053 18.5 0.9 0.0033 15.9 0.2 2.2 1 1 1 2 2 2 1 HI0933-like protein DAO PF01266.19 EMR71228.1 - 0.00092 18.2 0.0 0.081 11.8 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMR71228.1 - 0.0021 17.8 0.1 0.86 9.3 0.0 2.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EMR71228.1 - 0.0024 17.0 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EMR71228.1 - 0.015 15.3 2.2 2.1 8.3 1.1 2.7 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EMR71228.1 - 0.03 14.0 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 EMR71228.1 - 0.042 12.7 0.7 0.092 11.6 0.4 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EMR71228.1 - 0.096 12.7 0.4 0.22 11.5 0.3 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.20 EMR71229.1 - 9.4e-09 35.4 0.0 9.4e-09 35.4 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EMR71229.1 - 0.0006 19.8 0.0 0.0039 17.1 0.0 2.2 2 1 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EMR71229.1 - 0.01 15.4 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 KR domain tRNA-synt_1 PF00133.17 EMR71230.1 - 1.2e-176 588.3 0.4 1.1e-175 585.1 0.3 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMR71230.1 - 7.4e-19 67.9 0.0 2.5e-18 66.2 0.0 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EMR71230.1 - 1.8e-14 53.2 2.2 2.7e-08 32.8 0.1 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (M) RDV-p3 PF09231.5 EMR71230.1 - 0.069 10.5 0.0 0.098 10.0 0.0 1.1 1 0 0 1 1 1 0 Rice dwarf virus p3 Peptidase_M43 PF05572.8 EMR71232.1 - 1.9e-16 60.0 0.1 3e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EMR71232.1 - 0.00086 19.2 1.1 0.0019 18.1 0.7 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EMR71232.1 - 0.021 15.3 0.2 0.072 13.6 0.1 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMR71232.1 - 0.022 14.8 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like p450 PF00067.17 EMR71233.1 - 5.5e-36 124.0 0.0 7.8e-34 116.9 0.0 2.7 1 1 0 1 1 1 1 Cytochrome P450 NifU_N PF01592.11 EMR71233.1 - 0.032 14.1 0.3 20 5.1 0.0 3.3 2 1 1 3 3 3 0 NifU-like N terminal domain MFS_1 PF07690.11 EMR71234.1 - 5.9e-20 71.2 39.5 5.9e-20 71.2 27.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily COX14 PF14880.1 EMR71234.1 - 0.21 11.2 2.8 0.33 10.5 0.1 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly PMT PF02366.13 EMR71235.1 - 1.6e-78 263.5 18.8 2.2e-78 262.9 13.0 1.2 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EMR71235.1 - 4e-20 72.1 1.3 6.7e-20 71.4 0.7 1.5 1 1 0 1 1 1 1 MIR domain Lum_binding PF00677.12 EMR71236.1 - 3.1e-34 116.7 0.7 2.7e-16 59.2 0.1 2.6 2 1 0 2 2 2 2 Lumazine binding domain Bac_luciferase PF00296.15 EMR71237.1 - 2.5e-64 217.3 3.8 3.6e-64 216.7 2.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ERCC4 PF02732.10 EMR71238.1 - 2.2e-29 102.0 0.3 3e-29 101.6 0.2 1.2 1 0 0 1 1 1 1 ERCC4 domain Sugar_tr PF00083.19 EMR71239.1 - 3.4e-61 207.2 24.2 4.3e-61 206.8 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR71239.1 - 3.7e-15 55.4 35.5 7.7e-15 54.4 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR71239.1 - 5.3e-06 25.0 21.3 0.0013 17.2 0.3 3.5 1 1 1 3 3 3 2 MFS/sugar transport protein Ureide_permease PF07168.6 EMR71239.1 - 0.12 11.0 8.9 0.1 11.2 3.9 2.1 2 0 0 2 2 2 0 Ureide permease PhoD PF09423.5 EMR71240.1 - 1.1e-137 459.3 1.8 2.3e-137 458.2 1.2 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase Pilin_PilA PF14245.1 EMR71240.1 - 0.055 13.9 1.0 0.15 12.5 0.7 1.7 1 0 0 1 1 1 0 Type IV pilin PilA Ribonuc_L-PSP PF01042.16 EMR71241.1 - 7.5e-40 135.4 0.0 8.3e-40 135.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Methyltransf_31 PF13847.1 EMR71242.1 - 1.7e-12 47.1 0.1 2.9e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMR71242.1 - 1.2e-11 44.2 0.0 1.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 EMR71242.1 - 3e-10 39.6 0.0 4.9e-10 38.9 0.0 1.3 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 EMR71242.1 - 5.8e-09 36.5 0.0 1.4e-08 35.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR71242.1 - 1.1e-08 35.4 0.0 2.9e-08 34.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR71242.1 - 3.1e-08 33.6 0.0 9.3e-08 32.1 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EMR71242.1 - 3.9e-08 32.3 0.1 5.7e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EMR71242.1 - 1.3e-06 28.6 0.1 5.6e-06 26.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EMR71242.1 - 7.1e-06 25.5 0.0 1.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EMR71242.1 - 1.4e-05 24.8 0.0 3.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMR71242.1 - 3.4e-05 23.0 0.0 4.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EMR71242.1 - 0.00011 22.6 0.0 0.00021 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EMR71242.1 - 0.00019 21.4 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 EMR71242.1 - 0.0015 18.1 0.3 0.0025 17.4 0.2 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EMR71242.1 - 0.0062 16.2 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EMR71242.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RrnaAD PF00398.15 EMR71242.1 - 0.053 12.5 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.9 EMR71242.1 - 0.055 12.6 0.2 0.13 11.4 0.1 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 EMR71242.1 - 0.076 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.8 EMR71242.1 - 0.086 12.1 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 UPF0020 PF01170.13 EMR71242.1 - 0.096 12.2 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DNA_pol_B_palm PF14792.1 EMR71243.1 - 3.4e-33 114.0 0.0 6.6e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EMR71243.1 - 2e-21 75.4 0.0 3.5e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EMR71243.1 - 2.9e-20 71.5 0.3 7.2e-20 70.2 0.1 1.8 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EMR71243.1 - 6.9e-13 48.5 0.5 2.4e-12 46.8 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 EMR71243.1 - 0.0036 17.4 0.1 0.33 11.1 0.0 2.7 2 1 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EMR71243.1 - 0.011 16.0 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Cdd1 PF11731.3 EMR71243.1 - 0.029 14.2 0.1 4.1 7.4 0.1 2.7 1 1 0 1 1 1 0 Pathogenicity locus HHH_3 PF12836.2 EMR71243.1 - 0.12 12.3 0.3 27 4.8 0.0 2.8 2 1 0 2 2 2 0 Helix-hairpin-helix motif Ammonium_transp PF00909.16 EMR71245.1 - 1.9e-115 385.5 28.2 2.2e-115 385.3 19.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family PGM_PMM_I PF02878.11 EMR71246.1 - 2.3e-17 62.7 0.3 6.8e-08 32.0 0.0 3.0 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EMR71246.1 - 4.6e-14 52.6 0.1 4.3e-13 49.4 0.0 2.6 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EMR71246.1 - 4.7e-10 39.3 0.1 1.6e-09 37.6 0.1 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EMR71246.1 - 5.9e-05 23.0 0.0 0.00034 20.6 0.0 2.4 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III MFS_1 PF07690.11 EMR71247.1 - 3.5e-13 48.9 8.0 3.5e-13 48.9 5.5 2.6 1 1 2 3 3 3 1 Major Facilitator Superfamily DUF2416 PF10315.4 EMR71247.1 - 1.1 9.5 5.6 0.2 11.9 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2416) Per1 PF04080.8 EMR71248.1 - 8.6e-104 346.6 11.2 1.1e-103 346.3 7.8 1.1 1 0 0 1 1 1 1 Per1-like zf-C2H2 PF00096.21 EMR71252.1 - 0.011 16.0 2.8 0.011 16.0 1.9 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR71252.1 - 0.056 13.7 17.4 0.069 13.5 0.9 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger NUP50 PF08911.6 EMR71252.1 - 0.71 10.2 4.8 2.1 8.8 0.7 2.9 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) PEP_mutase PF13714.1 EMR71253.1 - 6.5e-44 149.9 0.3 7.4e-44 149.7 0.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EMR71253.1 - 2.1e-19 69.1 0.2 2.9e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF4267 PF14087.1 EMR71254.1 - 1.7e-14 53.3 4.9 5.2e-14 51.7 3.4 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4267) NAD_synthase PF02540.12 EMR71254.1 - 0.16 10.8 0.1 0.23 10.3 0.1 1.2 1 0 0 1 1 1 0 NAD synthase Aconitase PF00330.15 EMR71255.1 - 5.6e-56 189.9 0.0 1.1e-37 129.5 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) NB-ARC PF00931.17 EMR71256.1 - 1.1e-07 31.0 0.0 0.0013 17.6 0.0 2.1 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.1 EMR71256.1 - 0.0028 17.7 0.0 0.0067 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMR71256.1 - 0.012 15.5 0.1 0.07 13.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EMR71256.1 - 0.067 12.2 0.2 0.59 9.2 0.0 2.2 3 0 0 3 3 3 0 Zeta toxin Seryl_tRNA_N PF02403.17 EMR71257.1 - 0.1 12.6 2.0 0.11 12.4 1.4 1.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Dynein_light PF01221.13 EMR71257.1 - 0.27 11.2 2.5 0.37 10.7 1.5 1.4 1 1 0 1 1 1 0 Dynein light chain type 1 Terpene_synth_C PF03936.11 EMR71258.1 - 0.0012 18.1 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Transket_pyr PF02779.19 EMR71260.1 - 5.1e-46 156.3 0.0 7.6e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EMR71260.1 - 2.3e-35 121.2 0.1 1.2e-34 118.8 0.0 2.2 2 0 0 2 2 2 1 Transketolase, C-terminal domain PTR2 PF00854.16 EMR71261.1 - 1.2e-26 93.3 0.6 1.2e-25 90.0 0.4 2.1 1 1 0 1 1 1 1 POT family AA_permease_2 PF13520.1 EMR71262.1 - 2.7e-35 121.7 44.1 3e-35 121.5 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMR71262.1 - 9.6e-17 60.4 33.9 1.3e-16 60.0 23.5 1.0 1 0 0 1 1 1 1 Amino acid permease Gly_transf_sug PF04488.10 EMR71263.1 - 2.1e-08 34.4 0.0 4.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EMR71263.1 - 0.0044 16.2 0.0 0.0063 15.7 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Aldedh PF00171.17 EMR71264.1 - 2.4e-180 599.7 0.8 2.8e-180 599.6 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EMR71264.1 - 0.18 11.0 0.0 4.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF2051 PF09738.4 EMR71264.1 - 0.18 11.0 0.1 0.27 10.4 0.1 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Lysozyme_like PF13702.1 EMR71265.1 - 0.029 13.8 0.4 0.074 12.5 0.3 1.7 1 1 0 1 1 1 0 Lysozyme-like Abhydrolase_3 PF07859.8 EMR71266.1 - 1.4e-17 63.9 0.0 2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR71266.1 - 4.3e-05 23.2 0.0 5.6e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EMR71266.1 - 0.00014 20.5 0.0 0.0027 16.2 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EMR71266.1 - 0.00031 20.0 0.0 0.14 11.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 EMR71266.1 - 0.027 13.1 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Bd3614_N PF14442.1 EMR71266.1 - 0.13 12.2 1.7 0.22 11.4 1.2 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal DUF3245 PF11595.3 EMR71266.1 - 2.7 8.2 5.2 4 7.7 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) DUF2856 PF11043.3 EMR71267.1 - 0.54 10.4 3.6 1.4 9.0 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2856) Oxysterol_BP PF01237.13 EMR71268.1 - 3e-88 295.7 0.0 3.8e-88 295.3 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein zf-CCCH PF00642.19 EMR71269.1 - 1.4e-08 34.2 17.8 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EMR71269.1 - 3.7e-05 23.4 0.0 5.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR71269.1 - 0.004 16.7 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR71269.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PAXNEB PF05625.6 EMR71270.1 - 1.5e-95 320.1 0.0 1.6e-95 320.0 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RRM_1 PF00076.17 EMR71272.1 - 3.9e-24 84.0 0.2 1.4e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR71272.1 - 3.8e-16 58.8 0.0 3.8e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR71272.1 - 5.7e-14 51.7 0.1 4.3e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR71274.1 - 7.4e-31 105.6 0.0 1.8e-14 53.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR71274.1 - 5e-16 58.4 0.0 1.3e-06 28.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR71274.1 - 1.5e-13 50.4 0.0 7.6e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EMR71274.1 - 0.0029 17.0 1.5 0.3 10.5 0.1 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain Hexapep PF00132.19 EMR71275.1 - 1.5e-14 52.7 17.2 5e-10 38.4 1.8 4.2 1 1 4 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMR71275.1 - 6.9e-07 28.7 10.9 1.4e-06 27.7 1.6 2.9 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase SQS_PSY PF00494.14 EMR71277.1 - 9.3e-36 123.4 0.0 1.8e-35 122.5 0.0 1.5 2 0 0 2 2 2 1 Squalene/phytoene synthase Abhydrolase_5 PF12695.2 EMR71278.1 - 1.2e-06 28.3 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EMR71278.1 - 8.7e-05 21.1 0.1 0.00079 18.0 0.1 1.9 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 EMR71278.1 - 0.0013 17.9 0.0 0.0025 17.0 0.0 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EMR71278.1 - 0.039 13.1 0.0 0.084 12.0 0.0 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.15 EMR71278.1 - 0.054 12.9 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 EMR71278.1 - 0.1 11.9 0.0 0.39 10.1 0.0 1.9 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EMR71278.1 - 0.52 10.1 6.7 1.8 8.4 4.6 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Aa_trans PF01490.13 EMR71279.1 - 8.4e-44 149.6 34.5 1e-43 149.3 23.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.1 EMR71279.1 - 0.0063 16.1 3.0 0.0063 16.1 2.1 3.0 3 0 0 3 3 3 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase SH3_9 PF14604.1 EMR71280.1 - 1.7e-29 101.1 2.8 3e-14 52.3 0.1 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EMR71280.1 - 6.6e-24 83.0 5.3 2.3e-11 42.9 0.2 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EMR71280.1 - 2.8e-16 58.7 0.0 7e-08 31.8 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EMR71280.1 - 6.6e-10 38.9 0.0 1.2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein zf-H2C2_2 PF13465.1 EMR71281.1 - 4.1e-07 29.9 9.2 4.1e-06 26.8 0.7 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EMR71281.1 - 0.00021 21.4 0.3 0.00021 21.4 0.2 3.4 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR71281.1 - 0.00033 20.7 8.4 0.0007 19.7 0.2 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EMR71281.1 - 0.63 10.2 3.5 4.7 7.4 0.3 2.8 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HET PF06985.6 EMR71283.1 - 8.1e-20 71.3 10.4 1e-18 67.8 7.2 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Choline_kinase PF01633.15 EMR71285.1 - 3e-27 95.5 0.0 4e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase HAD_2 PF13419.1 EMR71287.1 - 6.9e-23 81.7 0.0 9.3e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR71287.1 - 3e-11 44.1 0.0 1.5e-10 41.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR71287.1 - 4e-07 29.6 0.0 9.9e-07 28.3 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 EMR71287.1 - 0.00062 19.9 0.0 0.00073 19.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EMR71287.1 - 0.0062 16.3 0.0 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 EMR71287.1 - 0.071 12.7 0.0 9.6 5.8 0.0 2.2 1 1 1 2 2 2 0 NLI interacting factor-like phosphatase Radical_SAM PF04055.16 EMR71287.1 - 0.074 13.2 0.0 0.3 11.2 0.0 1.9 1 1 0 1 1 1 0 Radical SAM superfamily MutS_V PF00488.16 EMR71288.1 - 1.2e-55 188.4 0.0 2.8e-55 187.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EMR71288.1 - 1e-05 25.4 0.0 2.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain III Calreticulin PF00262.13 EMR71289.1 - 1.3e-151 504.3 35.5 3.1e-149 496.6 13.9 2.5 2 1 1 3 3 3 2 Calreticulin family SLT PF01464.15 EMR71290.1 - 0.0059 16.1 1.9 0.041 13.3 1.3 2.1 1 1 0 1 1 1 1 Transglycosylase SLT domain Proteasome PF00227.21 EMR71291.1 - 9.1e-48 162.0 0.1 1.1e-47 161.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF3222 PF11519.3 EMR71291.1 - 0.08 12.9 0.7 9 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) Acetyltransf_1 PF00583.19 EMR71292.1 - 5e-10 39.2 1.7 3.5e-09 36.5 1.1 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR71292.1 - 3.6e-08 33.4 0.1 6e-08 32.7 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR71292.1 - 7.2e-08 32.5 0.2 1.9e-07 31.2 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR71292.1 - 0.00018 21.1 0.4 0.00058 19.5 0.3 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EMR71292.1 - 0.0086 16.2 0.1 0.02 15.0 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMR71292.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EMR71292.1 - 0.12 12.2 0.4 0.3 10.9 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR71292.1 - 0.12 12.1 0.9 0.64 9.8 0.4 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain p450 PF00067.17 EMR71293.1 - 1.2e-72 244.8 0.0 2.9e-72 243.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Phosphoprotein PF00922.12 EMR71293.1 - 0.019 14.1 0.3 0.03 13.5 0.2 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Aldolase_II PF00596.16 EMR71294.1 - 2e-39 135.0 0.0 2.4e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Plasmodium_Vir PF05795.6 EMR71295.1 - 0.15 11.2 2.3 0.4 9.8 1.6 1.7 1 1 0 1 1 1 0 Plasmodium vivax Vir protein CorA PF01544.13 EMR71296.1 - 1.8e-11 43.6 0.8 2.4e-10 39.9 0.1 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein MMgT PF10270.4 EMR71297.1 - 5.7e-35 119.9 0.0 6.8e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter FAD_binding_4 PF01565.18 EMR71298.1 - 2.5e-23 82.0 3.4 5.2e-23 81.0 2.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR71298.1 - 0.014 15.2 0.3 0.051 13.5 0.0 2.0 2 0 0 2 2 2 0 Berberine and berberine like Peptidase_M22 PF00814.20 EMR71299.1 - 5.5e-09 35.9 0.0 8.5e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 Glycoprotease family Myc_N PF01056.13 EMR71299.1 - 0.0025 17.0 2.2 0.0036 16.5 1.5 1.2 1 0 0 1 1 1 1 Myc amino-terminal region Nucleoplasmin PF03066.10 EMR71299.1 - 0.034 13.6 2.2 0.051 13.0 1.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 EMR71299.1 - 0.043 12.2 3.8 0.054 11.9 2.6 1.0 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 EMR71299.1 - 0.11 12.8 3.3 0.18 12.1 2.3 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Afi1 PF07792.7 EMR71299.1 - 0.22 11.5 4.9 0.36 10.8 3.4 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PPP4R2 PF09184.6 EMR71299.1 - 0.22 11.0 15.2 0.31 10.5 10.5 1.1 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.7 EMR71299.1 - 2.5 7.2 5.9 3.3 6.8 4.1 1.1 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.11 EMR71300.1 - 3.3e-22 78.7 63.5 8.3e-17 60.9 21.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR71300.1 - 1.1e-06 27.1 24.8 1.5e-06 26.7 15.9 1.8 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF912 PF06024.7 EMR71300.1 - 0.052 13.6 1.0 0.35 10.9 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) AAA_12 PF13087.1 EMR71302.1 - 3.1e-35 121.3 0.0 5.4e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EMR71302.1 - 4.4e-29 101.7 0.1 1.1e-28 100.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EMR71302.1 - 2.2e-11 43.7 0.2 6e-09 35.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMR71302.1 - 2.5e-10 39.9 0.2 6.4e-10 38.6 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EMR71302.1 - 4.4e-05 23.3 0.6 0.00013 21.8 0.1 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EMR71302.1 - 0.0007 18.9 3.2 0.0077 15.5 2.2 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 EMR71302.1 - 0.0032 16.7 0.1 0.0063 15.7 0.1 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.1 EMR71302.1 - 0.0096 15.9 0.2 0.056 13.4 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMR71302.1 - 0.021 14.9 0.1 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EMR71302.1 - 0.034 13.1 0.0 0.034 13.1 0.0 2.4 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 EMR71302.1 - 0.038 12.8 0.1 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_25 PF13481.1 EMR71302.1 - 0.061 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EMR71302.1 - 0.082 12.0 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiC DEAD PF00270.24 EMR71302.1 - 0.15 11.5 1.7 0.33 10.4 1.2 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase DNA_primase_lrg PF04104.9 EMR71303.1 - 1.4e-74 250.6 0.0 2e-74 250.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit EIF_2_alpha PF07541.7 EMR71305.1 - 3.7e-33 113.6 0.0 8.5e-33 112.4 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EMR71305.1 - 1.9e-11 43.9 0.4 3.4e-11 43.0 0.3 1.5 1 0 0 1 1 1 1 S1 RNA binding domain FAD-oxidase_C PF02913.14 EMR71307.1 - 1.7e-57 194.5 0.0 2.6e-57 193.9 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMR71307.1 - 3e-36 123.9 0.5 5.3e-36 123.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain ADH_N PF08240.7 EMR71308.1 - 1.4e-25 89.1 2.7 2.3e-25 88.4 1.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR71308.1 - 2.4e-15 56.2 0.0 8.5e-15 54.4 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EMR71308.1 - 0.0022 17.1 0.2 0.0039 16.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-Tim10_DDP PF02953.10 EMR71309.1 - 1.4e-22 78.7 1.1 1.8e-22 78.3 0.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Toxin_1 PF00087.16 EMR71309.1 - 0.039 14.3 0.2 0.054 13.8 0.2 1.2 1 0 0 1 1 1 0 Snake toxin WD40 PF00400.27 EMR71310.1 - 4.4e-46 153.1 15.8 8.1e-09 35.0 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 EMR71310.1 - 7.9e-11 41.5 0.4 1.6e-10 40.4 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMR71310.1 - 8.5e-08 31.6 0.0 1.8e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EMR71310.1 - 9.5e-08 30.6 0.4 0.0063 14.7 0.0 3.8 1 1 3 4 4 4 2 Nucleoporin Nup120/160 FlaG PF03646.10 EMR71310.1 - 0.0026 17.9 0.2 0.41 10.8 0.0 4.0 6 0 0 6 6 6 1 FlaG protein Cytochrom_D1 PF02239.11 EMR71310.1 - 0.013 13.7 0.0 0.029 12.6 0.0 1.6 1 0 0 1 1 1 0 Cytochrome D1 heme domain PQQ_2 PF13360.1 EMR71310.1 - 0.017 14.6 0.0 0.11 11.9 0.0 2.1 1 1 0 1 1 1 0 PQQ-like domain ANTH PF07651.11 EMR71311.1 - 8.7e-67 224.7 0.6 1.1e-66 224.4 0.4 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EMR71311.1 - 2e-07 30.9 0.0 3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 ENTH domain PAT1 PF09770.4 EMR71311.1 - 2.6 6.1 46.0 3.1 5.9 31.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MAT1 PF06391.8 EMR71312.1 - 1.2e-23 83.7 11.0 1.6e-23 83.3 7.6 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EMR71312.1 - 0.0025 17.4 5.4 0.0049 16.4 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR71312.1 - 0.035 13.8 8.9 0.12 12.1 6.2 1.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EMR71312.1 - 0.045 13.4 5.7 0.088 12.4 3.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMR71312.1 - 0.053 13.5 5.9 0.12 12.4 4.1 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Phage_Mu_F PF04233.9 EMR71312.1 - 0.11 13.0 0.1 0.11 13.0 0.1 2.6 3 1 1 4 4 4 0 Phage Mu protein F like protein zf-RING_2 PF13639.1 EMR71312.1 - 0.5 10.2 7.0 1.3 8.9 4.8 1.7 1 1 0 1 1 1 0 Ring finger domain tRNA-synt_2 PF00152.15 EMR71313.1 - 4e-94 315.1 0.0 6.1e-93 311.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EMR71313.1 - 0.0011 18.5 0.4 0.094 12.2 0.2 2.2 1 1 1 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 EMR71313.1 - 0.17 11.0 0.0 0.79 8.8 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) CS PF04969.11 EMR71314.1 - 5.8e-19 68.4 0.0 1.6e-18 66.9 0.0 1.8 2 0 0 2 2 2 1 CS domain Prefoldin_3 PF13758.1 EMR71315.1 - 1.1e-26 92.5 4.5 1.8e-26 91.7 1.9 2.3 1 1 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 EMR71315.1 - 1.6e-17 64.2 0.2 1.6e-17 64.2 0.2 5.9 6 2 1 7 7 7 1 Domain of unknown function (DUF3835) Prefoldin_2 PF01920.15 EMR71315.1 - 0.00058 19.5 5.3 0.2 11.4 0.3 3.0 2 0 0 2 2 2 2 Prefoldin subunit Prefoldin PF02996.12 EMR71315.1 - 0.053 13.1 5.6 2.6 7.7 0.4 2.9 2 1 1 3 3 3 0 Prefoldin subunit NPV_P10 PF05531.7 EMR71315.1 - 0.13 12.4 2.5 4.2 7.6 0.1 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 EMR71315.1 - 0.2 11.8 4.5 0.84 9.7 3.1 2.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GAS PF13851.1 EMR71315.1 - 0.49 9.5 13.3 0.012 14.8 3.4 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 EMR71315.1 - 0.64 7.7 2.6 1.3 6.7 1.8 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-CCCH PF00642.19 EMR71316.1 - 0.016 14.9 1.6 0.016 14.9 1.1 3.7 3 1 1 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GTP_EFTU PF00009.22 EMR71317.1 - 6e-39 133.4 3.7 2.7e-38 131.2 2.5 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EMR71317.1 - 6.6e-26 90.3 0.1 1.6e-25 89.1 0.1 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EMR71317.1 - 3.5e-11 43.0 0.8 2.8e-06 27.3 0.0 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EMR71317.1 - 4.6e-08 33.0 0.2 1.1e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EMR71317.1 - 2.2e-06 28.1 0.1 5.6e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein IF2_N PF04760.10 EMR71317.1 - 4.9e-05 22.8 0.6 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region PduV-EutP PF10662.4 EMR71317.1 - 0.0003 20.2 0.4 0.0008 18.9 0.2 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 EMR71317.1 - 0.00069 18.8 0.1 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMR71317.1 - 0.0014 17.9 0.2 0.0034 16.6 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EMR71317.1 - 0.002 17.3 0.4 0.0067 15.7 0.3 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3854 PF12965.2 EMR71317.1 - 0.0027 17.3 0.1 0.031 13.9 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3854) Dynamin_N PF00350.18 EMR71317.1 - 0.056 13.2 0.9 4 7.2 0.0 2.9 2 1 1 3 3 3 0 Dynamin family TPR_12 PF13424.1 EMR71318.1 - 2.4e-09 36.9 7.9 7.2e-05 22.6 0.2 5.8 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR71318.1 - 4.5e-09 36.5 3.3 0.00021 21.5 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMR71318.1 - 7e-08 31.8 14.0 0.09 12.7 0.0 7.4 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EMR71318.1 - 9.3e-08 31.3 5.3 0.098 12.3 0.0 5.8 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EMR71318.1 - 2.1e-07 30.4 8.8 0.0077 15.8 0.2 5.1 5 1 1 6 6 5 3 TPR repeat TPR_8 PF13181.1 EMR71318.1 - 4.4e-07 29.2 0.0 1.1 9.2 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMR71318.1 - 2.3e-05 23.8 0.1 0.0077 15.9 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EMR71318.1 - 0.0012 19.3 9.7 1.5 9.6 0.1 7.0 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_4 PF07721.9 EMR71318.1 - 0.0062 16.8 1.3 3.1 8.4 0.0 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMR71318.1 - 0.0075 16.9 18.8 0.067 13.8 0.1 6.6 6 3 1 7 7 5 1 Tetratricopeptide repeat DUF3856 PF12968.2 EMR71318.1 - 0.015 15.1 0.1 0.089 12.6 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_17 PF13431.1 EMR71318.1 - 0.024 14.8 0.0 1.5e+02 2.9 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ERK-JNK_inhib PF15002.1 EMR71318.1 - 0.068 12.5 0.0 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 ERK and JNK pathways, inhibitor TPR_10 PF13374.1 EMR71318.1 - 0.16 11.9 10.1 2.1 8.3 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.7 EMR71318.1 - 3.2 7.6 4.9 11 5.9 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat NAD_binding_9 PF13454.1 EMR71319.1 - 1.5e-46 157.9 0.0 3e-46 157.0 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMR71319.1 - 0.1 11.4 0.0 0.43 9.4 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) p450 PF00067.17 EMR71320.1 - 7e-22 77.5 0.0 9.5e-22 77.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 EMR71321.1 - 8e-45 152.9 0.0 9.5e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR71321.1 - 1.5e-23 83.7 0.0 2.5e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR71321.1 - 5.2e-06 26.0 0.0 1.1e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR71321.1 - 3.8e-05 22.5 0.0 5.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EMR71321.1 - 0.041 14.3 0.1 0.079 13.3 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EMR71321.1 - 0.046 13.6 0.4 0.1 12.5 0.3 1.6 1 0 0 1 1 1 0 short chain dehydrogenase ABC_tran PF00005.22 EMR71322.1 - 6.4e-49 165.7 0.0 2.6e-24 86.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EMR71322.1 - 1.3e-47 161.7 34.7 2.4e-28 98.7 6.0 3.1 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.1 EMR71322.1 - 6.8e-17 62.3 1.0 4.5e-05 23.5 0.0 4.2 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.1 EMR71322.1 - 1e-09 38.6 0.4 0.00054 20.0 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EMR71322.1 - 2.5e-09 36.7 0.5 0.0042 16.3 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EMR71322.1 - 7.7e-08 31.6 1.8 0.0069 15.5 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EMR71322.1 - 1.1e-07 31.2 1.7 0.0066 15.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EMR71322.1 - 2.5e-07 30.8 0.1 0.029 14.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EMR71322.1 - 2.5e-07 31.2 0.2 0.0037 17.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMR71322.1 - 5.2e-07 29.2 0.8 0.054 12.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EMR71322.1 - 6.8e-07 28.6 0.0 0.8 8.6 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_28 PF13521.1 EMR71322.1 - 7.7e-06 25.9 1.8 0.015 15.2 0.1 2.9 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 EMR71322.1 - 8.4e-06 25.5 0.0 0.084 12.5 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.1 EMR71322.1 - 1e-05 25.2 0.3 0.0057 16.3 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EMR71322.1 - 1.2e-05 26.1 0.0 0.32 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EMR71322.1 - 1.2e-05 25.1 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase SbcCD_C PF13558.1 EMR71322.1 - 1.8e-05 24.5 1.1 0.26 11.2 0.0 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 EMR71322.1 - 2.7e-05 23.2 0.8 0.047 12.6 0.1 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_30 PF13604.1 EMR71322.1 - 4e-05 23.2 0.5 0.044 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EMR71322.1 - 5.9e-05 22.6 1.6 0.21 11.0 0.1 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 EMR71322.1 - 7e-05 22.4 4.3 0.058 12.8 0.2 2.6 2 0 0 2 2 2 2 AAA-like domain UPF0079 PF02367.12 EMR71322.1 - 0.0002 20.9 1.4 0.26 10.9 0.1 2.7 3 0 0 3 3 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EMR71322.1 - 0.0003 21.1 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 EMR71322.1 - 0.00035 20.0 3.4 0.17 11.3 0.3 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EMR71322.1 - 0.00041 20.2 0.1 0.87 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EMR71322.1 - 0.00075 19.2 0.7 0.96 9.1 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EMR71322.1 - 0.00083 19.8 0.1 2.6 8.5 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 EMR71322.1 - 0.00093 19.4 0.2 3 8.0 0.0 3.2 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMR71322.1 - 0.001 18.8 1.5 3.4 7.3 0.1 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 EMR71322.1 - 0.0019 17.2 0.0 0.39 9.6 0.0 2.2 2 0 0 2 2 2 1 KAP family P-loop domain ATP_bind_1 PF03029.12 EMR71322.1 - 0.002 17.6 0.4 0.55 9.7 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 EMR71322.1 - 0.0032 17.1 2.2 0.44 10.2 0.1 3.6 4 1 0 4 4 4 1 NTPase RNA_helicase PF00910.17 EMR71322.1 - 0.0047 17.0 0.1 2.1 8.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Pox_A32 PF04665.7 EMR71322.1 - 0.0062 15.8 0.9 1.3 8.2 0.0 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_24 PF13479.1 EMR71322.1 - 0.0081 15.7 1.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EMR71322.1 - 0.0099 15.8 1.2 4.5 7.2 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase PDR_CDR PF06422.7 EMR71322.1 - 0.011 15.3 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 CDR ABC transporter ABC_ATPase PF09818.4 EMR71322.1 - 0.016 13.7 0.1 1.2 7.6 0.0 2.9 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 EMR71322.1 - 0.017 14.2 0.5 3.6 6.6 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 EMR71322.1 - 0.027 14.3 0.1 13 5.6 0.1 2.8 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.20 EMR71322.1 - 0.037 13.5 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.13 EMR71322.1 - 0.04 12.9 0.2 5.7 5.8 0.0 2.2 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 EMR71322.1 - 0.05 13.0 0.8 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EMR71322.1 - 0.053 13.3 0.6 5.2 6.8 0.0 2.9 3 0 0 3 3 2 0 Dynamin family PRK PF00485.13 EMR71322.1 - 0.055 13.0 0.1 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_35 PF14516.1 EMR71322.1 - 0.078 11.6 0.0 9 4.8 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain PhoH PF02562.11 EMR71322.1 - 0.079 12.1 0.5 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein SRP54 PF00448.17 EMR71322.1 - 0.082 12.3 2.2 4.9 6.5 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.12 EMR71322.1 - 0.19 11.0 0.1 2.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Thymidylate kinase DUF927 PF06048.6 EMR71322.1 - 0.21 10.8 2.0 0.17 11.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF927) DUF2075 PF09848.4 EMR71322.1 - 0.26 10.2 0.1 7.1 5.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Gtr1_RagA PF04670.7 EMR71322.1 - 0.27 10.3 0.3 23 4.0 0.2 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF367 PF04034.8 EMR71323.1 - 1e-45 154.4 0.0 1.4e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EMR71323.1 - 2.6e-12 46.0 0.9 6.3e-12 44.8 0.6 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI S_layer_N PF05123.7 EMR71324.1 - 0.027 14.1 0.1 0.04 13.5 0.1 1.2 1 0 0 1 1 1 0 S-layer like family, N-terminal region FAD_binding_4 PF01565.18 EMR71325.1 - 6.6e-19 67.7 0.1 1e-17 63.8 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR71325.1 - 0.0093 15.8 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like TauD PF02668.11 EMR71325.1 - 0.085 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family TPR_17 PF13431.1 EMR71326.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4215 PF13948.1 EMR71326.1 - 1.2 9.4 9.0 2 8.6 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) Mitofilin PF09731.4 EMR71326.1 - 4.3 5.8 7.3 4.9 5.6 5.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Acyl_transf_3 PF01757.17 EMR71327.1 - 5.2e-25 88.0 29.1 8.6e-25 87.2 20.2 1.4 1 0 0 1 1 1 1 Acyltransferase family VHS PF00790.14 EMR71328.1 - 5.8e-45 152.3 0.1 2.1e-44 150.5 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EMR71328.1 - 1e-22 79.9 0.1 2.8e-22 78.6 0.1 1.7 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 EMR71328.1 - 6.9e-20 71.4 0.2 1.3e-19 70.6 0.2 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain DUF3328 PF11807.3 EMR71329.1 - 6e-23 81.6 2.0 7.5e-23 81.3 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NMO PF03060.10 EMR71330.1 - 1.2e-39 136.4 4.8 6.4e-39 134.0 3.3 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EMR71330.1 - 1.4e-06 27.4 0.1 0.00082 18.3 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EMR71330.1 - 3.5e-06 26.1 0.6 5.6e-06 25.5 0.4 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.13 EMR71330.1 - 1.9e-05 23.6 6.0 2.9e-05 23.0 4.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Methyltransf_20 PF12147.3 EMR71330.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase CENP-B_dimeris PF09026.5 EMR71331.1 - 0.09 13.0 12.1 0.13 12.5 8.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HSP90 PF00183.13 EMR71331.1 - 0.24 9.7 9.7 0.28 9.5 6.8 1.0 1 0 0 1 1 1 0 Hsp90 protein Sporozoite_P67 PF05642.6 EMR71331.1 - 0.25 9.1 7.7 0.25 9.1 5.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.8 EMR71331.1 - 0.25 10.9 8.1 0.28 10.7 5.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Rpp20 PF12328.3 EMR71331.1 - 0.44 10.2 6.1 0.59 9.7 4.2 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P GOLD_2 PF13897.1 EMR71331.1 - 0.47 10.6 5.4 0.65 10.2 3.7 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CobT PF06213.7 EMR71331.1 - 0.48 9.5 11.2 0.48 9.5 7.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 EMR71331.1 - 0.56 8.8 11.1 0.55 8.9 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EMR71331.1 - 0.56 8.1 7.7 0.58 8.1 5.3 1.0 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 EMR71331.1 - 0.6 8.9 5.8 0.61 8.9 4.0 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nop14 PF04147.7 EMR71331.1 - 1.7 6.4 12.9 1.6 6.5 8.9 1.0 1 0 0 1 1 1 0 Nop14-like family Rhabdo_ncap PF00945.13 EMR71331.1 - 1.8 7.0 4.2 2 6.9 2.9 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF2890 PF11081.3 EMR71331.1 - 1.8 8.5 11.9 1.9 8.4 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) TRAP_alpha PF03896.11 EMR71331.1 - 3.1 6.6 7.9 3.4 6.6 5.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit AF1Q PF15017.1 EMR71331.1 - 4.1 7.3 10.4 6 6.8 7.2 1.3 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Daxx PF03344.10 EMR71331.1 - 4.2 5.7 13.5 4.2 5.7 9.3 1.0 1 0 0 1 1 1 0 Daxx Family COPI_C PF06957.6 EMR71331.1 - 4.7 5.6 6.3 4.3 5.7 4.4 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus NOG1 PF06858.9 EMR71332.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) FMN_dh PF01070.13 EMR71333.1 - 6.5e-86 288.3 2.0 4.9e-83 278.9 1.4 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EMR71333.1 - 0.00014 20.9 0.6 0.00051 19.0 0.4 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EMR71333.1 - 0.0048 16.0 1.3 0.0048 16.0 0.9 1.6 2 0 0 2 2 2 1 Nitronate monooxygenase Glu_synthase PF01645.12 EMR71333.1 - 0.016 14.1 0.2 0.041 12.8 0.1 1.6 1 1 0 1 1 1 0 Conserved region in glutamate synthase His_biosynth PF00977.16 EMR71333.1 - 0.022 14.0 0.9 1.9 7.6 0.0 2.6 2 1 1 3 3 3 0 Histidine biosynthesis protein DHO_dh PF01180.16 EMR71333.1 - 0.026 13.4 1.5 1.4 7.8 0.0 2.2 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase Trp_syntA PF00290.15 EMR71333.1 - 0.085 11.3 0.1 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain MatE PF01554.13 EMR71334.1 - 3.4e-49 166.5 29.0 1.3e-32 112.6 6.2 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EMR71334.1 - 1.8e-05 24.5 31.3 3.5e-05 23.6 0.7 4.5 2 2 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MVIN PF03023.9 EMR71334.1 - 4.5e-05 22.0 6.0 4.5e-05 22.0 4.2 2.0 1 1 0 2 2 2 1 MviN-like protein Como_SCP PF02248.11 EMR71334.1 - 0.08 12.2 0.2 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Small coat protein Methyltransf_33 PF10017.4 EMR71335.1 - 9.7e-24 83.6 0.0 1.8e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent SRCR PF00530.13 EMR71335.1 - 0.0033 17.7 1.6 0.008 16.4 0.6 1.9 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain DUF995 PF06191.7 EMR71335.1 - 0.15 11.4 0.8 0.26 10.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF995) Fungal_trans PF04082.13 EMR71336.1 - 3.2e-12 45.8 0.0 3.3e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EMR71338.1 - 5.6e-12 45.8 0.6 2.7e-11 43.6 0.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR71338.1 - 1.1e-05 25.3 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR71338.1 - 0.00061 19.5 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 KR domain DJ-1_PfpI PF01965.19 EMR71340.1 - 9.9e-29 99.6 0.3 1.5e-28 99.1 0.2 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EMR71340.1 - 1.1e-09 37.6 0.0 2.9e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 EMR71340.1 - 0.0031 16.8 0.0 0.0053 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 EMR71340.1 - 0.0036 16.8 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.11 EMR71341.1 - 6.7e-32 110.5 21.1 1.1e-31 109.9 14.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DPM3 PF08285.6 EMR71341.1 - 0.05 13.4 0.2 4.1 7.3 0.3 2.6 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) ADH_N PF08240.7 EMR71342.1 - 2e-11 43.6 0.1 6.3e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR71342.1 - 3e-10 39.7 0.3 7.2e-10 38.5 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 EMR71344.1 - 0.0091 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF588 PF04535.7 EMR71345.1 - 0.084 12.4 0.4 0.16 11.5 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF588) AMP-binding PF00501.23 EMR71346.1 - 0 1774.6 5.3 6.2e-84 281.7 0.0 8.6 7 2 1 8 8 8 8 AMP-binding enzyme Condensation PF00668.15 EMR71346.1 - 0 1099.4 0.2 6.1e-44 150.0 0.0 11.9 10 2 1 11 11 11 10 Condensation domain PP-binding PF00550.20 EMR71346.1 - 5.3e-94 308.4 0.5 1.5e-12 47.6 0.0 7.9 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EMR71346.1 - 8e-37 126.0 0.5 0.0005 20.9 0.0 8.1 7 0 0 7 7 7 7 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EMR71346.1 - 2.9e-14 53.1 0.2 0.018 15.3 0.0 5.7 5 0 0 5 5 5 3 HxxPF-repeated domain AATase PF07247.7 EMR71346.1 - 0.078 11.5 0.0 41 2.5 0.0 5.0 8 0 0 8 8 8 0 Alcohol acetyltransferase ASC PF00858.19 EMR71346.1 - 4.1 5.9 0.0 30 3.1 0.0 2.1 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel MFS_1 PF07690.11 EMR71347.1 - 5.4e-18 64.8 31.5 6.6e-18 64.5 21.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Dexa_ind PF15198.1 EMR71347.1 - 0.67 9.9 4.7 1.3 8.9 0.1 2.8 3 0 0 3 3 3 0 Dexamethasone-induced MFS_1 PF07690.11 EMR71349.1 - 1.6e-43 148.7 49.2 1.6e-43 148.7 34.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily eIF2A PF08662.6 EMR71350.1 - 2.8e-78 262.0 0.0 5.7e-77 257.8 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EMR71350.1 - 0.0001 22.0 1.1 5.3 7.0 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat CDV3 PF15359.1 EMR71350.1 - 0.024 14.6 0.4 0.024 14.6 0.3 3.0 3 1 0 3 3 3 0 Carnitine deficiency-associated protein 3 Proteasome_A_N PF10584.4 EMR71350.1 - 0.26 10.6 2.7 6.9 6.0 0.2 3.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PP28 PF10252.4 EMR71351.1 - 6.9e-26 90.0 20.8 6.9e-26 90.0 14.4 3.2 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 DUF3237 PF11578.3 EMR71351.1 - 0.098 11.9 0.2 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) CAF-1_p150 PF11600.3 EMR71351.1 - 2.8 7.2 50.7 0.52 9.6 21.8 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MEA1 PF06910.6 EMR71351.1 - 3.8 7.1 13.5 2.9 7.5 7.9 1.8 1 1 1 2 2 2 0 Male enhanced antigen 1 (MEA1) GMC_oxred_C PF05199.8 EMR71352.1 - 1.9e-37 128.7 0.0 2.8e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR71352.1 - 9.9e-25 87.2 0.0 1.4e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DUF1996 PF09362.5 EMR71353.1 - 3e-78 262.7 0.7 4.1e-78 262.2 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Podoplanin PF05808.6 EMR71354.1 - 7.8e-05 22.2 0.5 0.00015 21.4 0.3 1.4 1 0 0 1 1 1 1 Podoplanin VSP PF03302.8 EMR71354.1 - 0.0017 17.0 0.8 0.0023 16.6 0.6 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein DAP10 PF07213.6 EMR71354.1 - 0.062 13.0 2.0 0.15 11.8 0.2 2.1 2 0 0 2 2 2 0 DAP10 membrane protein Methyltransf_2 PF00891.13 EMR71355.1 - 5.8e-40 136.9 0.1 9.6e-40 136.2 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase DUF3328 PF11807.3 EMR71355.1 - 1.1e-12 48.1 0.8 2.2e-12 47.1 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_23 PF13489.1 EMR71355.1 - 0.00027 20.7 0.0 0.0034 17.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR71355.1 - 0.00072 20.1 0.0 0.0027 18.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain HTH_AsnC-type PF13404.1 EMR71355.1 - 0.023 14.2 0.3 0.077 12.5 0.0 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Chromate_transp PF02417.10 EMR71357.1 - 1.5e-48 164.5 33.1 3.2e-27 95.1 9.4 2.6 3 0 0 3 3 3 2 Chromate transporter Asparaginase PF00710.15 EMR71358.1 - 4.1e-68 229.5 0.1 4.9e-68 229.3 0.1 1.0 1 0 0 1 1 1 1 Asparaginase Aa_trans PF01490.13 EMR71360.1 - 1.9e-74 250.5 29.9 2.3e-74 250.3 20.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein tRNA_SAD PF07973.9 EMR71361.1 - 3.3e-06 26.8 0.8 8.4e-06 25.5 0.6 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 EMR71361.1 - 6.3e-06 24.7 0.1 8.1e-06 24.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) ABC_tran PF00005.22 EMR71362.1 - 3.7e-34 117.9 0.0 1e-33 116.5 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EMR71362.1 - 1.9e-22 79.9 15.6 2.9e-22 79.3 10.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EMR71362.1 - 5.4e-07 29.8 0.0 0.00021 21.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EMR71362.1 - 3e-05 23.3 0.9 0.0019 17.4 0.1 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMR71362.1 - 0.0004 19.8 0.2 0.00095 18.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EMR71362.1 - 0.0024 18.0 0.7 0.019 15.1 0.5 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMR71362.1 - 0.0029 16.8 0.2 0.0079 15.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EMR71362.1 - 0.027 14.4 0.6 0.078 12.9 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.1 EMR71362.1 - 0.064 13.1 0.4 0.35 10.8 0.3 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EMR71362.1 - 0.084 12.2 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EMR71362.1 - 0.31 10.4 2.6 0.54 9.6 0.1 2.4 2 1 0 3 3 3 0 AAA-like domain Glyco_hydro_12 PF01670.11 EMR71363.1 - 5.2e-44 149.7 0.8 9.2e-44 148.9 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 p450 PF00067.17 EMR71364.1 - 1.4e-68 231.5 0.0 1.6e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CAAD PF14159.1 EMR71364.1 - 0.15 11.7 0.0 13 5.4 0.0 2.4 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Amidohydro_1 PF01979.15 EMR71365.1 - 3.1e-18 66.5 1.1 3.2e-10 40.1 0.1 2.9 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EMR71365.1 - 1.8e-17 64.2 0.5 7.1e-17 62.3 0.3 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EMR71365.1 - 2.1e-10 40.2 0.0 5.3e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMR71365.1 - 7.9e-07 28.6 1.9 0.00054 19.2 0.0 2.8 2 2 0 2 2 2 2 Amidohydrolase family Methyltransf_33 PF10017.4 EMR71366.1 - 2.1e-26 92.2 0.0 2e-25 89.1 0.0 2.1 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.1 EMR71366.1 - 0.084 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EMR71366.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain zf-Nse PF11789.3 EMR71367.1 - 3 7.4 5.9 81 2.8 0.1 4.2 4 1 1 5 5 5 0 Zinc-finger of the MIZ type in Nse subunit Cyto_heme_lyase PF01265.12 EMR71367.1 - 3.7 7.0 5.1 16 5.0 3.4 1.9 1 1 1 2 2 2 0 Cytochrome c/c1 heme lyase MMR_HSR1 PF01926.18 EMR71368.1 - 9.1e-10 38.5 0.0 2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EMR71368.1 - 2.2e-06 26.9 0.1 2.2e-06 26.9 0.1 1.7 2 0 0 2 2 2 1 AIG1 family Septin PF00735.13 EMR71368.1 - 4.7e-05 22.5 0.6 8.3e-05 21.7 0.0 1.6 2 0 0 2 2 2 1 Septin Miro PF08477.8 EMR71368.1 - 0.0001 22.7 0.3 0.00028 21.3 0.0 1.9 2 0 0 2 2 1 1 Miro-like protein Dynamin_N PF00350.18 EMR71368.1 - 0.00031 20.5 4.6 0.37 10.5 0.0 3.2 2 1 1 3 3 3 2 Dynamin family FeoB_N PF02421.13 EMR71368.1 - 0.00055 19.2 0.1 0.0011 18.3 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EMR71368.1 - 0.0015 17.7 0.2 0.0055 15.8 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EMR71368.1 - 0.0024 18.6 0.6 0.0095 16.7 0.1 2.2 1 1 1 2 2 2 1 AAA domain NB-ARC PF00931.17 EMR71368.1 - 0.003 16.4 1.0 0.0047 15.8 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain cobW PF02492.14 EMR71368.1 - 0.004 16.6 0.4 0.061 12.7 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF4460 PF14687.1 EMR71368.1 - 0.0056 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) AAA_22 PF13401.1 EMR71368.1 - 0.0075 16.4 0.2 0.041 14.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EMR71368.1 - 0.0076 16.5 0.5 0.017 15.4 0.0 1.9 2 1 0 2 2 2 1 ABC transporter AAA_33 PF13671.1 EMR71368.1 - 0.0083 16.0 0.1 0.04 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMR71368.1 - 0.012 15.9 1.1 0.036 14.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF4407 PF14362.1 EMR71368.1 - 0.021 13.7 2.7 0.026 13.4 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PduV-EutP PF10662.4 EMR71368.1 - 0.036 13.5 0.0 0.076 12.4 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CtIP_N PF10482.4 EMR71368.1 - 0.045 13.5 3.3 0.099 12.4 2.3 1.6 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain ATP_bind_1 PF03029.12 EMR71368.1 - 0.048 13.1 0.5 0.048 13.1 0.3 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 EMR71368.1 - 0.056 13.7 2.6 1 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EMR71368.1 - 0.066 13.0 7.4 0.36 10.6 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 Cytochrom_C_2 PF01322.15 EMR71368.1 - 0.067 13.7 8.4 0.66 10.5 3.2 2.7 1 1 2 3 3 3 0 Cytochrome C' RICH PF05062.7 EMR71368.1 - 0.15 12.2 0.2 0.15 12.2 0.2 2.8 3 0 0 3 3 3 0 RICH domain SRPRB PF09439.5 EMR71368.1 - 0.15 11.2 1.5 0.37 9.9 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MobB PF03205.9 EMR71368.1 - 0.24 11.0 2.0 0.27 10.9 0.3 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 EMR71368.1 - 0.33 9.6 3.3 1 8.0 0.1 2.4 2 1 1 3 3 3 0 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.22 EMR71368.1 - 0.56 9.6 4.4 1.7 8.0 0.6 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain STAT_alpha PF01017.15 EMR71368.1 - 0.61 9.7 6.5 0.95 9.1 4.5 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain ABC_tran_2 PF12848.2 EMR71368.1 - 2.2 8.1 8.1 4.3 7.2 5.3 1.7 1 1 0 1 1 1 0 ABC transporter RVT_thumb PF06817.9 EMR71368.1 - 3.3 7.3 5.5 47 3.6 0.3 3.2 3 0 0 3 3 3 0 Reverse transcriptase thumb domain AAA_10 PF12846.2 EMR71368.1 - 5 6.4 6.5 86 2.4 4.5 2.3 1 1 0 1 1 1 0 AAA-like domain DUF4024 PF13216.1 EMR71370.1 - 0.076 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) Ank_2 PF12796.2 EMR71372.1 - 1.5e-78 259.1 2.2 4.6e-15 55.7 0.0 7.4 4 2 0 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EMR71372.1 - 1.7e-57 188.5 10.5 6.4e-06 25.7 0.0 16.7 17 0 0 17 17 17 11 Ankyrin repeat Ank_4 PF13637.1 EMR71372.1 - 1.2e-42 143.5 4.8 2.2e-05 24.8 0.0 12.5 9 4 4 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR71372.1 - 8.3e-42 137.0 4.8 0.00081 19.3 0.0 15.8 16 0 0 16 16 16 8 Ankyrin repeat Ank_5 PF13857.1 EMR71372.1 - 3.4e-37 125.6 18.9 0.0001 22.4 0.0 13.8 7 4 8 15 15 15 11 Ankyrin repeats (many copies) DUF3447 PF11929.3 EMR71372.1 - 0.0025 17.5 0.0 12 5.8 0.0 4.5 5 1 0 5 5 5 1 Domain of unknown function (DUF3447) Macoilin PF09726.4 EMR71372.1 - 1.2 7.3 2.9 1.9 6.6 2.0 1.2 1 0 0 1 1 1 0 Transmembrane protein NUDIX PF00293.23 EMR71373.1 - 1.3e-14 54.0 0.0 2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EMR71373.1 - 0.011 15.1 0.0 0.033 13.5 0.0 1.8 2 0 0 2 2 2 0 NUDIX domain Serglycin PF04360.7 EMR71373.1 - 0.043 13.5 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Serglycin adh_short PF00106.20 EMR71374.1 - 2.2e-19 69.9 0.3 3.9e-19 69.1 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR71374.1 - 1.1e-05 25.3 0.0 1.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR71374.1 - 2.6e-05 23.9 3.1 0.001 18.7 0.4 2.2 2 0 0 2 2 2 2 KR domain Eno-Rase_NADH_b PF12242.3 EMR71374.1 - 0.00026 20.7 0.2 0.0036 17.0 0.2 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Bac_luciferase PF00296.15 EMR71374.1 - 0.0061 15.7 0.1 0.0082 15.2 0.1 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase THF_DHG_CYH_C PF02882.14 EMR71374.1 - 0.049 12.7 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2524 PF10732.4 EMR71375.1 - 0.11 12.6 0.1 0.4 10.8 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) Glyco_hydro_49 PF03718.8 EMR71376.1 - 2.4e-196 653.3 22.5 3.1e-196 652.9 15.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 Imm21 PF15569.1 EMR71376.1 - 1.1 9.0 5.7 0.32 10.7 0.3 2.7 3 0 0 3 3 3 0 Immunity protein 21 ADH_zinc_N PF00107.21 EMR71377.1 - 9.9e-27 93.0 0.1 1.6e-26 92.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR71377.1 - 7.5e-06 26.8 0.0 1.1e-05 26.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_3 PF03447.11 EMR71377.1 - 0.013 15.8 0.2 0.013 15.8 0.1 2.0 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain SIR2 PF02146.12 EMR71378.1 - 1.2e-35 122.8 0.0 1.9e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EMR71378.1 - 0.0032 17.2 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Glyco_transf_28 PF03033.15 EMR71378.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain COX5B PF01215.14 EMR71379.1 - 5.1e-37 126.5 0.0 6.7e-37 126.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb NapD PF03927.8 EMR71380.1 - 0.037 13.8 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 NapD protein AIG2 PF06094.7 EMR71381.1 - 5.4e-10 39.6 0.0 8.8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family Aldo_ket_red PF00248.16 EMR71382.1 - 5.8e-38 130.3 0.0 2.4e-27 95.4 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family Trp_DMAT PF11991.3 EMR71382.1 - 0.046 12.9 0.0 0.062 12.5 0.0 1.1 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase SOBP PF15279.1 EMR71385.1 - 0.00015 22.2 0.7 0.00024 21.6 0.5 1.3 1 0 0 1 1 1 1 Sine oculis-binding protein Ras PF00071.17 EMR71385.1 - 0.00084 18.7 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Ras family F-box PF00646.28 EMR71385.1 - 0.021 14.4 0.1 0.048 13.3 0.1 1.5 1 0 0 1 1 1 0 F-box domain MIP-T3 PF10243.4 EMR71385.1 - 2.6 6.3 9.9 3.5 5.9 6.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 His_Phos_2 PF00328.17 EMR71386.1 - 7.6e-28 97.8 0.0 9.4e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.20 EMR71387.1 - 2.1e-24 86.0 0.0 9.4e-22 77.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR71387.1 - 3.7e-05 22.9 0.0 6.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Methyltransf_11 PF08241.7 EMR71389.1 - 5.3e-15 55.6 0.0 1.6e-14 54.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR71389.1 - 5.2e-14 52.0 0.0 6.8e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR71389.1 - 5.6e-12 45.6 0.0 7.7e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR71389.1 - 2.5e-11 43.8 0.0 4.6e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR71389.1 - 7.6e-11 41.5 0.0 1.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMR71389.1 - 5e-09 36.5 0.0 1e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR71389.1 - 4.7e-08 33.5 0.0 9.9e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR71389.1 - 2e-07 31.0 0.0 3.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR71389.1 - 0.0012 18.2 0.0 0.045 13.1 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase small domain MetW PF07021.7 EMR71389.1 - 0.043 13.2 0.0 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Diphthamide_syn PF01866.12 EMR71390.1 - 2.7e-113 378.2 0.0 3.3e-113 378.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Glyco_hydro_35 PF01301.14 EMR71392.1 - 2.4e-79 266.9 3.8 2.1e-77 260.5 2.7 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EMR71392.1 - 7.7e-61 204.6 1.4 1.5e-60 203.7 1.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EMR71392.1 - 1.6e-39 134.5 6.8 6.5e-20 71.4 0.9 3.3 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EMR71392.1 - 7.4e-25 86.1 0.0 1.8e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.10 EMR71392.1 - 1.9e-07 30.5 2.7 1.6e-05 24.2 1.0 2.9 1 1 1 2 2 2 1 Beta-galactosidase Abhydrolase_6 PF12697.2 EMR71393.1 - 2.2e-12 47.3 0.9 2.2e-12 47.3 0.6 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR71393.1 - 1.6e-05 24.6 0.0 2.7e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR71393.1 - 3.1e-05 23.6 0.0 5.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.20 EMR71394.1 - 0.00014 21.8 0.2 0.001 19.0 0.0 2.2 2 1 1 3 3 3 1 short chain dehydrogenase Dopey_N PF04118.9 EMR71394.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Dopey, N-terminal DUF3506 PF12014.3 EMR71397.1 - 9.3e-45 151.7 0.0 1.4e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 EMR71397.1 - 4.2e-07 29.5 0.9 4.2e-07 29.5 0.6 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EMR71397.1 - 0.00059 19.4 0.1 0.0014 18.2 0.1 1.7 1 1 1 2 2 2 1 F-box domain DUF1581 PF07619.6 EMR71397.1 - 0.054 13.4 0.0 16 5.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1581) F-box-like_2 PF13013.1 EMR71397.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 F-box-like domain Pex14_N PF04695.8 EMR71398.1 - 0.0062 16.5 23.6 1.9 8.5 0.0 5.3 5 0 0 5 5 5 3 Peroxisomal membrane anchor protein (Pex14p) conserved region Phage-Gp8 PF09215.5 EMR71398.1 - 0.02 14.0 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage T4, Gp8 Methyltransf_14 PF08484.6 EMR71398.1 - 0.14 11.6 1.2 6.2 6.3 0.1 2.7 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain RPW8 PF05659.6 EMR71398.1 - 0.38 10.3 2.4 0.7 9.4 0.2 2.2 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3994 PF13159.1 EMR71398.1 - 1.3 9.2 0.0 1.3 9.2 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3994) Glyco_hydro_18 PF00704.23 EMR71400.1 - 1.6e-14 54.1 1.7 4.8e-14 52.5 0.1 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 Ank_2 PF12796.2 EMR71401.1 - 5.2e-30 103.6 1.6 9.4e-09 35.5 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EMR71401.1 - 1.6e-22 78.0 1.3 4.4e-06 26.2 0.0 6.9 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.1 EMR71401.1 - 1.2e-19 70.3 0.8 5.6e-06 26.7 0.1 6.8 4 2 4 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR71401.1 - 9.1e-19 65.6 0.2 2.1e-05 24.2 0.0 7.4 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 EMR71401.1 - 2.4e-11 43.4 1.7 0.7 10.2 0.0 6.8 6 1 1 7 7 7 3 Ankyrin repeats (many copies) F-box PF00646.28 EMR71401.1 - 0.0021 17.6 0.0 0.006 16.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain TFIIA PF03153.8 EMR71401.1 - 0.022 14.6 21.1 0.027 14.3 14.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EMR71401.1 - 6.5 4.5 39.1 8.6 4.1 27.1 1.2 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 EMR71401.1 - 6.6 5.7 33.3 5 6.1 21.9 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT GST_C_2 PF13410.1 EMR71402.1 - 0.0011 18.7 1.5 0.0019 18.0 1.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMR71402.1 - 0.0031 17.4 0.0 0.0072 16.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_M14 PF00246.19 EMR71403.1 - 5.5e-43 147.5 0.1 7.6e-43 147.1 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase NAD_binding_1 PF00175.16 EMR71405.1 - 1.1e-09 38.8 0.0 2.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.17 EMR71405.1 - 5.5e-09 36.3 0.1 4.3e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.19 EMR71405.1 - 1.8e-08 34.4 0.0 8e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EMR71405.1 - 0.011 15.6 0.4 0.51 10.2 0.0 3.2 3 1 0 4 4 4 0 Ferric reductase NAD binding domain Protoglobin PF11563.3 EMR71405.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Protoglobin Cupin_2 PF07883.6 EMR71406.1 - 6.4e-09 35.2 0.0 9.1e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EMR71406.1 - 0.0015 17.9 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) GPI PF06560.6 EMR71406.1 - 0.0079 15.2 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) AraC_binding PF02311.14 EMR71406.1 - 0.078 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Ammonium_transp PF00909.16 EMR71407.1 - 1.3e-67 227.9 19.8 1.8e-67 227.5 13.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family MFS_1 PF07690.11 EMR71408.1 - 7.1e-46 156.5 32.5 7.1e-46 156.5 22.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR71408.1 - 3.1e-10 39.2 5.8 3.1e-10 39.2 4.0 3.2 3 1 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.15 EMR71408.1 - 0.24 9.4 6.8 0.42 8.5 1.1 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1769 PF08588.5 EMR71409.1 - 7.7e-29 99.4 0.6 1.4e-28 98.5 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) NESP55 PF06390.7 EMR71409.1 - 0.083 12.2 6.8 0.13 11.5 4.7 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF4611 PF15387.1 EMR71409.1 - 1.8 8.7 11.4 5.7 7.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SOG2 PF10428.4 EMR71409.1 - 5 5.6 5.9 6.6 5.2 4.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CTP_transf_2 PF01467.21 EMR71410.1 - 0.00021 21.3 1.1 0.00091 19.3 0.8 2.1 1 1 0 1 1 1 1 Cytidylyltransferase PK PF00224.16 EMR71412.1 - 9.9e-168 557.1 3.9 1.5e-167 556.5 2.7 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EMR71412.1 - 6.8e-29 99.7 0.0 1.9e-28 98.3 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EMR71412.1 - 0.00029 19.8 0.8 0.001 17.9 0.3 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EMR71412.1 - 0.023 13.6 0.0 0.55 9.0 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Ank_4 PF13637.1 EMR71413.1 - 4.1e-17 62.1 0.0 0.002 18.5 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.25 EMR71413.1 - 5.4e-17 60.6 0.4 0.0017 18.1 0.0 7.8 8 0 0 8 8 8 4 Ankyrin repeat Ank_2 PF12796.2 EMR71413.1 - 1.2e-16 60.7 0.0 5e-08 33.1 0.0 5.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMR71413.1 - 3.7e-13 48.3 0.0 0.0015 18.6 0.0 7.0 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.1 EMR71413.1 - 4.7e-11 42.5 0.1 0.085 13.1 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeats (many copies) UPF0242 PF06785.6 EMR71414.1 - 0.061 11.9 1.5 0.067 11.8 1.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) UBN2_2 PF14227.1 EMR71414.1 - 0.076 12.5 0.1 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Apolipoprotein PF01442.13 EMR71414.1 - 0.12 11.8 4.0 0.15 11.5 2.7 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF972 PF06156.8 EMR71414.1 - 5.4 7.4 5.9 8 6.8 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) adh_short_C2 PF13561.1 EMR71415.1 - 5.4e-25 88.5 0.0 6.8e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR71415.1 - 6.4e-21 74.9 3.8 9.3e-21 74.4 2.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR71415.1 - 3.5e-10 39.8 1.2 5.7e-10 39.1 0.8 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR71415.1 - 1.9e-05 24.2 0.0 4.8e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR71415.1 - 0.019 13.8 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.14 EMR71415.1 - 0.023 13.4 0.1 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 EMR71415.1 - 0.073 13.1 0.1 0.073 13.1 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EMR71415.1 - 0.09 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.16 EMR71415.1 - 0.17 11.7 0.7 0.31 10.8 0.4 1.6 1 1 0 1 1 1 0 ThiF family DUF1748 PF08520.5 EMR71416.1 - 4.6e-33 112.6 0.1 5.6e-33 112.4 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) WD40 PF00400.27 EMR71417.1 - 2.1e-21 74.9 8.1 3.2e-08 33.1 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Beta-lactamase PF00144.19 EMR71418.1 - 1.9e-48 165.1 2.7 2.6e-48 164.7 1.8 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EMR71418.1 - 4.3e-06 26.5 0.0 2.2e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) Acyl_transf_3 PF01757.17 EMR71419.1 - 0.03 13.1 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Acyltransferase family DUF1183 PF06682.7 EMR71419.1 - 0.058 12.9 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) RCR PF12273.3 EMR71419.1 - 0.32 11.5 2.6 0.39 11.2 0.0 2.3 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red THRAP3_BCLAF1 PF15440.1 EMR71419.1 - 0.93 8.0 4.0 1.5 7.4 2.7 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF3099 PF11298.3 EMR71420.1 - 2.4 7.9 6.5 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) zf-rbx1 PF12678.2 EMR71421.1 - 2.2e-06 27.6 1.0 3.1e-06 27.1 0.7 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EMR71421.1 - 2.4e-06 27.2 6.4 9.8e-06 25.3 4.4 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EMR71421.1 - 1.3e-05 24.7 2.9 3.1e-05 23.5 2.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMR71421.1 - 6.7e-05 22.4 0.8 0.00016 21.2 0.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMR71421.1 - 9.7e-05 22.3 0.4 9.7e-05 22.3 0.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMR71421.1 - 0.00093 18.9 0.5 0.0014 18.4 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EMR71421.1 - 0.0014 18.2 4.3 0.0033 17.1 3.0 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Pellino PF04710.9 EMR71421.1 - 0.024 13.2 0.1 0.033 12.8 0.1 1.1 1 0 0 1 1 1 0 Pellino zf-RING_UBOX PF13445.1 EMR71421.1 - 0.081 12.6 0.3 0.22 11.2 0.1 1.9 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 EMR71421.1 - 0.49 10.3 3.4 1.7 8.6 2.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EMR71421.1 - 1.3 8.9 4.1 0.56 10.1 0.2 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING adh_short PF00106.20 EMR71422.1 - 1.7e-10 41.0 0.7 2.3e-09 37.3 0.5 2.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR71422.1 - 2.9e-10 40.3 0.0 6.5e-10 39.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR71422.1 - 0.0016 18.1 0.1 0.0041 16.8 0.0 1.8 2 0 0 2 2 2 1 KR domain Glyco_hydro_61 PF03443.9 EMR71424.1 - 1.5e-47 162.2 0.2 3.5e-47 161.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EMR71424.1 - 1.8e-11 43.5 11.5 1.8e-11 43.5 7.9 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain Kinesin PF00225.18 EMR71426.1 - 1.5e-56 191.5 0.0 2e-31 108.9 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain AAA_16 PF13191.1 EMR71426.1 - 0.43 10.5 3.0 0.56 10.1 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain SRP40_C PF05022.7 EMR71427.1 - 2.4e-25 88.8 0.3 2.4e-25 88.8 0.2 2.3 2 0 0 2 2 2 1 SRP40, C-terminal domain adh_short PF00106.20 EMR71428.1 - 1.6e-14 54.1 1.2 2.8e-14 53.3 0.8 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR71428.1 - 5.1e-05 23.0 0.5 8e-05 22.3 0.4 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMR71428.1 - 0.0094 15.7 1.7 0.064 13.0 0.7 2.5 2 1 1 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EMR71430.1 - 5.5e-12 46.0 0.1 7.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR71430.1 - 2.1e-07 30.6 0.0 4.8e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.5 EMR71430.1 - 1.4e-05 23.7 0.0 3.1e-05 22.6 0.0 1.5 1 1 1 2 2 2 1 HIM1 NmrA PF05368.8 EMR71430.1 - 4e-05 22.9 0.0 0.00015 21.1 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EMR71430.1 - 0.0034 16.3 0.1 0.097 11.5 0.0 2.4 1 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EMR71430.1 - 0.0073 15.0 0.0 0.032 12.9 0.0 1.9 1 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family A_deaminase PF00962.17 EMR71431.1 - 1.2e-08 34.2 3.9 0.0012 17.8 2.5 3.2 2 1 0 2 2 2 2 Adenosine/AMP deaminase GH-E PF14410.1 EMR71431.1 - 0.04 14.0 0.5 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues 2OG-FeII_Oxy_2 PF13532.1 EMR71432.1 - 1.2e-32 113.3 0.0 1.9e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EMR71432.1 - 0.002 18.5 0.0 0.0041 17.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PEX11 PF05648.9 EMR71433.1 - 8e-22 77.5 2.7 2e-10 40.3 1.3 3.8 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Cyclin_N PF00134.18 EMR71434.1 - 2.6e-13 49.6 0.0 4.1e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EMR71434.1 - 3.3e-10 40.5 0.0 6.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin NAD_binding_8 PF13450.1 EMR71435.1 - 2.6e-13 49.7 0.2 7.4e-13 48.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMR71435.1 - 1.9e-05 23.6 0.9 2.8e-05 23.1 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EMR71435.1 - 2.8e-05 23.3 0.0 4.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EMR71435.1 - 2.9e-05 23.1 0.8 7.2e-05 21.8 0.6 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR71435.1 - 5e-05 23.4 0.0 0.0059 16.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR71435.1 - 0.00017 20.2 0.2 0.00027 19.5 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EMR71435.1 - 0.00021 21.2 0.0 0.00044 20.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMR71435.1 - 0.00059 19.0 0.0 0.0011 18.1 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 EMR71435.1 - 0.0011 18.1 0.2 0.0019 17.3 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EMR71435.1 - 0.0034 17.7 0.3 0.015 15.6 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMR71435.1 - 0.0081 15.2 0.4 0.014 14.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EMR71435.1 - 0.025 13.4 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 EMR71435.1 - 0.15 12.1 0.1 0.49 10.3 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain DHBP_synthase PF00926.14 EMR71436.1 - 4.5e-72 241.3 0.0 3.1e-71 238.6 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Methyltransf_23 PF13489.1 EMR71437.1 - 1e-19 70.8 0.0 1.7e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR71437.1 - 3.3e-15 56.3 0.0 5.1e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR71437.1 - 1.3e-13 51.4 0.0 2.1e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR71437.1 - 6.3e-13 48.5 0.0 8.5e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR71437.1 - 3.3e-12 46.7 0.0 6.1e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR71437.1 - 1.3e-08 34.8 0.1 6.5e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR71437.1 - 3.4e-07 30.5 0.0 5.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EMR71437.1 - 0.00019 20.6 0.0 0.00026 20.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EMR71437.1 - 0.00045 19.6 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EMR71437.1 - 0.0026 16.8 0.0 0.0051 15.9 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EMR71437.1 - 0.015 14.4 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.6 EMR71437.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.14 EMR71437.1 - 0.092 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3439 PF11921.3 EMR71437.1 - 8.3 6.1 8.4 2.3 8.0 3.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Hexapep PF00132.19 EMR71438.1 - 7.2e-10 37.9 8.0 6.5e-06 25.4 0.4 3.6 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EMR71438.1 - 0.00011 21.6 4.3 0.19 11.3 0.2 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase HET PF06985.6 EMR71440.1 - 9.2e-28 97.1 0.0 1.8e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Complex1_51K PF01512.12 EMR71441.1 - 2.1e-47 160.6 0.0 3.3e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EMR71441.1 - 3e-17 61.4 1.0 3e-17 61.4 0.7 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EMR71441.1 - 3.9e-09 36.2 0.0 9.2e-09 35.0 0.0 1.7 1 0 0 1 1 1 1 SLBB domain Rad4 PF03835.10 EMR71442.1 - 1.2e-11 44.1 2.3 1.8e-11 43.6 1.6 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EMR71442.1 - 1.7e-09 37.8 0.9 4.3e-09 36.5 0.6 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Pkinase PF00069.20 EMR71443.1 - 3e-71 239.6 0.0 3.9e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR71443.1 - 2.6e-31 108.6 0.0 3.3e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR71443.1 - 0.0032 16.4 0.0 0.0057 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMR71443.1 - 0.0035 17.1 0.1 0.01 15.6 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EMR71443.1 - 0.017 13.9 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EMR71443.1 - 0.13 11.3 0.0 0.38 9.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EMR71443.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL adh_short PF00106.20 EMR71444.1 - 1.5e-22 80.2 0.3 1.8e-22 80.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR71444.1 - 4.4e-07 29.7 0.7 8.4e-07 28.8 0.5 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR71444.1 - 8.2e-07 29.0 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.12 EMR71444.1 - 0.00019 20.3 0.1 0.00029 19.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EMR71444.1 - 0.0074 15.7 0.1 0.021 14.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family p450 PF00067.17 EMR71445.1 - 4.7e-45 153.9 0.0 8.3e-39 133.3 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 HET PF06985.6 EMR71446.1 - 2.4e-23 82.8 0.0 4.2e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ASCH PF04266.9 EMR71449.1 - 0.0024 18.2 0.0 0.0046 17.3 0.0 1.5 1 0 0 1 1 1 1 ASCH domain PAS_9 PF13426.1 EMR71450.1 - 1.5e-13 51.0 0.0 2.2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 EMR71450.1 - 0.0023 17.9 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EMR71450.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.6 1 1 0 1 1 1 0 PAS fold PAS_3 PF08447.6 EMR71450.1 - 0.026 14.6 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 PAS fold NUDIX PF00293.23 EMR71451.1 - 1.7e-06 27.6 0.0 2.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_6 PF12697.2 EMR71452.1 - 3.5e-25 89.2 0.9 8e-25 88.0 0.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR71452.1 - 3.4e-05 23.5 0.0 4.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR71452.1 - 0.0047 16.6 0.0 0.0088 15.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EMR71452.1 - 0.08 11.4 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Ndr family HECT PF00632.20 EMR71453.1 - 9.9e-56 189.1 0.0 1.7e-55 188.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RRN3 PF05327.6 EMR71453.1 - 0.00044 18.5 13.8 0.00044 18.5 9.6 2.0 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 HEAT PF02985.17 EMR71453.1 - 0.00071 19.4 0.5 0.36 11.0 0.0 4.4 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.18 EMR71453.1 - 0.014 15.2 4.2 2.7 7.9 0.1 5.4 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EMR71453.1 - 0.014 14.7 0.1 0.18 11.1 0.0 2.6 2 0 0 2 2 2 0 CLASP N terminal Clr5 PF14420.1 EMR71453.1 - 0.15 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Clr5 domain FLO_LFY PF01698.11 EMR71453.1 - 7.1 5.3 11.5 13 4.4 7.9 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Astro_capsid PF03115.9 EMR71453.1 - 7.2 4.7 9.9 14 3.7 6.9 1.4 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Complex1_30kDa PF00329.14 EMR71455.1 - 4.5e-35 119.9 0.1 6.7e-35 119.4 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Pkinase PF00069.20 EMR71457.1 - 1.6e-06 27.5 0.0 3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain zf-RING_4 PF14570.1 EMR71458.1 - 3.1e-20 71.4 11.5 5.5e-20 70.6 7.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EMR71458.1 - 6.3e-09 35.3 0.1 2.9e-08 33.2 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR71458.1 - 2.8e-07 30.4 0.0 1.1e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EMR71458.1 - 3.1e-07 29.9 5.9 6e-07 29.0 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EMR71458.1 - 5.9e-06 25.6 2.7 6.9e-06 25.4 1.9 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EMR71458.1 - 1.4e-05 24.7 8.7 3.3e-05 23.6 6.0 1.6 1 0 0 1 1 1 1 Ring finger domain RRM_5 PF13893.1 EMR71458.1 - 3.9e-05 23.4 0.6 0.0001 22.0 0.1 1.9 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 EMR71458.1 - 0.0011 18.6 4.5 0.0024 17.5 3.1 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) FYVE_2 PF02318.11 EMR71458.1 - 0.0025 17.6 3.9 0.0025 17.6 2.7 2.3 1 1 1 2 2 2 1 FYVE-type zinc finger zf-RING_5 PF14634.1 EMR71458.1 - 0.0028 17.3 9.9 0.0068 16.1 6.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain SET_assoc PF11767.3 EMR71458.1 - 0.0067 15.7 0.2 0.021 14.1 0.0 1.8 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.1 EMR71458.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FYVE PF01363.16 EMR71458.1 - 0.015 15.1 6.4 0.04 13.8 4.4 1.8 1 1 0 1 1 1 0 FYVE zinc finger DUF576 PF04507.7 EMR71458.1 - 0.021 13.7 2.0 0.029 13.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF576 DUF1289 PF06945.8 EMR71458.1 - 0.027 13.9 2.1 0.087 12.3 1.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1289) Rad50_zn_hook PF04423.9 EMR71458.1 - 0.033 13.6 0.7 3.4 7.2 0.0 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4 PF00097.20 EMR71458.1 - 0.044 13.4 9.9 0.12 12.0 6.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMR71458.1 - 0.053 13.5 10.3 0.16 12.0 7.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 EMR71458.1 - 0.054 13.2 5.9 0.065 12.9 2.7 2.1 2 1 0 2 2 2 0 Zinc-binding RING-finger Prok-RING_4 PF14447.1 EMR71458.1 - 0.089 12.3 10.2 0.1 12.1 3.4 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RRM_3 PF08777.6 EMR71458.1 - 0.25 11.1 5.3 0.48 10.2 1.7 2.3 2 1 0 2 2 2 0 RNA binding motif DZR PF12773.2 EMR71458.1 - 0.72 9.7 8.3 14 5.6 6.0 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.1 EMR71458.1 - 1.6 8.6 11.9 28 4.6 8.5 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FYDLN_acid PF09538.5 EMR71458.1 - 6.4 7.4 7.7 23 5.6 5.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Glyco_hydro_32C PF08244.7 EMR71459.1 - 2.1e-19 69.6 0.4 4.1e-19 68.7 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.15 EMR71459.1 - 4.9e-16 58.9 0.0 8.4e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain GMC_oxred_N PF00732.14 EMR71460.1 - 7.9e-26 90.8 0.0 1.6e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR71460.1 - 1.4e-17 64.3 0.0 2.5e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMR71460.1 - 5.4e-06 25.5 2.4 5.2e-05 22.2 0.5 2.6 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 EMR71460.1 - 1.3e-05 25.1 0.3 0.018 14.9 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR71460.1 - 0.00036 19.1 2.7 0.0033 15.9 1.0 2.6 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 EMR71460.1 - 0.00054 19.9 0.1 0.0014 18.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR71460.1 - 0.00095 18.1 3.2 0.071 11.9 1.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EMR71460.1 - 0.0029 16.7 1.5 0.0059 15.7 0.3 1.9 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EMR71460.1 - 0.0047 16.0 3.2 0.0079 15.3 0.9 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR71460.1 - 0.0056 16.7 0.1 0.58 10.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR71460.1 - 0.057 12.2 0.2 0.057 12.2 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Sugar_tr PF00083.19 EMR71461.1 - 6.3e-112 374.4 28.9 7.4e-112 374.1 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR71461.1 - 3.6e-25 88.4 33.2 1.2e-23 83.4 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_LAMP2 PF06126.6 EMR71461.1 - 0.048 12.0 4.5 0.095 11.0 3.1 1.5 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 TspO_MBR PF03073.10 EMR71462.1 - 0.11 12.0 10.0 0.21 11.0 6.9 1.4 1 0 0 1 1 1 0 TspO/MBR family FAD_binding_4 PF01565.18 EMR71463.1 - 2e-10 40.2 1.6 3.6e-07 29.7 0.1 3.0 1 1 2 3 3 3 2 FAD binding domain BBE PF08031.7 EMR71463.1 - 0.00029 20.6 0.7 0.00065 19.5 0.5 1.6 1 0 0 1 1 1 1 Berberine and berberine like NmrA PF05368.8 EMR71464.1 - 3.6e-22 78.7 0.0 4.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR71464.1 - 1.1e-14 54.9 0.2 1.4e-14 54.5 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EMR71464.1 - 7.4e-06 25.1 0.0 9.4e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EMR71464.1 - 0.00022 20.7 0.1 0.00047 19.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR71464.1 - 0.0051 15.5 0.1 0.017 13.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EMR71464.1 - 0.089 13.2 0.1 0.28 11.6 0.1 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.11 EMR71465.1 - 5.8e-30 104.1 31.1 8.4e-30 103.6 21.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR71465.1 - 2.8e-05 22.8 15.2 2.8e-05 22.8 10.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1228 PF06779.9 EMR71465.1 - 9.5 6.3 9.9 0.34 10.9 0.7 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1228) C2 PF00168.25 EMR71466.1 - 2.1e-67 222.9 0.0 1.1e-19 70.0 0.0 5.5 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 EMR71466.1 - 0.012 15.7 0.0 0.05 13.7 0.0 2.1 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) Fructosamin_kin PF03881.9 EMR71467.1 - 2.7e-44 151.3 0.0 3.4e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase dCMP_cyt_deam_1 PF00383.17 EMR71467.1 - 3.9e-11 42.4 0.0 6.9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APH PF01636.18 EMR71467.1 - 2.3e-07 30.7 0.0 3.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family APOBEC_N PF08210.6 EMR71467.1 - 0.0021 17.6 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 EMR71467.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase p450 PF00067.17 EMR71468.1 - 3.3e-28 98.4 0.0 3.7e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Polyketide_cyc PF03364.15 EMR71468.1 - 0.093 12.7 0.5 0.33 10.9 0.3 2.2 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Fungal_trans PF04082.13 EMR71469.1 - 7.3e-14 51.2 0.1 1.3e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AvrPphF-ORF-2 PF09143.5 EMR71469.1 - 0.02 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AvrPphF-ORF-2 COesterase PF00135.23 EMR71470.1 - 3.9e-56 190.8 0.0 5e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR71470.1 - 0.0034 16.9 0.0 0.0085 15.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Spore_coat_CotO PF14153.1 EMR71472.1 - 0.29 10.5 7.7 0.61 9.5 5.3 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Glyco_hydro_3 PF00933.16 EMR71473.1 - 9.8e-58 195.4 0.0 1.2e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR71473.1 - 3e-43 147.9 0.0 4.4e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR71473.1 - 6.1e-15 54.9 0.2 1.1e-14 54.0 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Acyl_transf_1 PF00698.16 EMR71474.1 - 5.8e-58 196.7 0.0 9.3e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EMR71474.1 - 6.6e-58 196.2 0.0 1.1e-57 195.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 EMR71474.1 - 3e-40 138.3 0.1 1.3e-26 93.5 0.0 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMR71474.1 - 2.4e-33 114.4 0.1 6e-33 113.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EMR71474.1 - 3.8e-27 95.1 0.0 1.4e-26 93.2 0.0 2.0 2 0 0 2 2 1 1 KR domain adh_short PF00106.20 EMR71474.1 - 5.1e-17 62.2 0.0 1.6e-16 60.6 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EMR71474.1 - 1.6e-16 60.0 0.1 4.8e-16 58.4 0.1 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMR71474.1 - 9.4e-11 42.0 0.0 5.1e-10 39.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR71474.1 - 3.8e-08 33.2 0.0 1.1e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR71474.1 - 1.2e-06 29.0 0.0 5e-06 27.0 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 EMR71474.1 - 2.7e-06 27.5 0.1 9e-06 25.8 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 EMR71474.1 - 5.7e-06 27.2 0.0 1.9e-05 25.5 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR71474.1 - 1.8e-05 24.4 0.0 4.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.1 EMR71474.1 - 0.00014 21.4 0.0 0.00098 18.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR71474.1 - 0.00019 21.8 0.0 0.00084 19.7 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR71474.1 - 0.0039 16.3 0.0 0.0076 15.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DNA_gyraseB_C PF00986.16 EMR71474.1 - 0.059 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus DUF915 PF06028.6 EMR71474.1 - 0.47 9.5 0.0 1.2 8.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DDHD PF02862.12 EMR71475.1 - 0.085 12.6 6.5 0.096 12.4 4.5 1.1 1 0 0 1 1 1 0 DDHD domain DUF4614 PF15391.1 EMR71475.1 - 0.12 12.1 15.9 0.16 11.7 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF966 PF06136.8 EMR71475.1 - 0.5 9.7 11.8 0.59 9.4 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.4 EMR71475.1 - 1.8 6.7 16.7 1.9 6.6 11.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Na_trans_assoc PF06512.8 EMR71475.1 - 6.2 6.7 6.9 6.5 6.6 4.8 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Treslin_N PF15292.1 EMR71475.1 - 8.3 4.1 11.5 11 3.7 8.0 1.1 1 0 0 1 1 1 0 Treslin N-terminus ketoacyl-synt PF00109.21 EMR71476.1 - 1.3e-70 237.7 0.4 3.1e-70 236.5 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EMR71476.1 - 2.3e-59 200.0 0.5 2.3e-59 200.0 0.4 2.3 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EMR71476.1 - 2.9e-55 187.8 0.9 4.8e-55 187.1 0.7 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EMR71476.1 - 6.1e-47 159.6 1.9 1.6e-46 158.2 0.1 2.6 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EMR71476.1 - 2.7e-45 154.7 0.2 1.2e-44 152.6 0.0 2.1 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EMR71476.1 - 2.4e-38 130.6 0.2 1.2e-37 128.3 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EMR71476.1 - 5.9e-18 64.6 0.0 4.8e-17 61.7 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR71476.1 - 8.9e-11 42.7 0.1 1.9e-09 38.4 0.0 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMR71476.1 - 2.9e-07 30.8 0.0 7.2e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR71476.1 - 4.7e-07 29.6 0.0 1.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EMR71476.1 - 2.7e-06 27.0 0.0 7.3e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EMR71476.1 - 4.5e-06 27.0 0.0 1.9e-05 25.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR71476.1 - 0.00011 22.3 0.0 0.00063 19.9 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EMR71476.1 - 0.00017 20.6 0.1 0.0004 19.4 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 EMR71476.1 - 0.0053 17.1 0.0 0.023 15.0 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 EMR71476.1 - 0.014 14.1 0.0 0.027 13.1 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMR71476.1 - 0.032 13.1 0.0 0.058 12.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_31 PF13847.1 EMR71476.1 - 0.059 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EMR71478.1 - 1.7e-24 86.2 58.2 6.9e-16 57.9 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM171 PF15471.1 EMR71478.1 - 0.042 12.6 1.1 0.092 11.5 0.8 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF1304 PF06993.7 EMR71478.1 - 5.2 6.8 13.6 0.51 10.0 2.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1304) Sulfatase PF00884.18 EMR71479.1 - 6e-62 209.5 0.1 8.1e-62 209.1 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EMR71479.1 - 1.2e-09 38.0 2.0 1.6e-09 37.5 0.2 2.1 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EMR71479.1 - 0.0064 14.9 0.0 0.014 13.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 EMR71479.1 - 0.024 14.9 0.4 0.057 13.6 0.3 1.6 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Methyltransf_2 PF00891.13 EMR71480.1 - 1.8e-29 102.6 0.0 2.4e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EMR71480.1 - 8e-08 32.8 0.0 1.9e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR71480.1 - 2e-05 24.8 0.0 5.5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR71480.1 - 5.3e-05 23.2 0.4 0.00023 21.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR71480.1 - 0.00027 21.3 0.0 0.00057 20.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR71480.1 - 0.00033 20.2 0.0 0.00063 19.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR71480.1 - 0.00054 19.1 0.0 0.00091 18.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EMR71480.1 - 0.0031 16.8 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EMR71480.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EMR71480.1 - 0.026 14.0 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_32 PF13679.1 EMR71480.1 - 0.097 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EMR71480.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Fungal_trans PF04082.13 EMR71481.1 - 8.9e-09 34.5 0.2 1.7e-08 33.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_2 PF13639.1 EMR71483.1 - 2e-05 24.3 11.9 0.00014 21.6 4.5 2.5 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 EMR71483.1 - 0.15 12.1 6.4 0.85 9.7 1.9 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EMR71483.1 - 2.1 8.1 8.1 0.17 11.6 1.8 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EMR71483.1 - 4.2 7.4 9.5 7.3 6.7 4.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR71483.1 - 8.1 6.2 9.1 31 4.3 0.0 2.4 2 0 0 2 2 2 0 zinc-RING finger domain SAM_2 PF07647.12 EMR71484.1 - 5.2e-09 35.8 0.0 9.6e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMR71484.1 - 6.3e-05 23.0 0.1 0.00013 22.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ALIX_LYPXL_bnd PF13949.1 EMR71484.1 - 0.048 12.6 0.2 0.086 11.7 0.1 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV TPR_11 PF13414.1 EMR71485.1 - 8.5e-10 38.1 11.9 0.00032 20.2 0.0 3.7 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 EMR71485.1 - 1.1e-07 31.1 8.1 0.00084 18.8 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMR71485.1 - 6.4e-06 25.6 16.2 0.016 15.0 0.3 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMR71485.1 - 2e-05 24.4 13.8 0.19 11.6 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMR71485.1 - 5.3e-05 23.5 14.4 2.4 9.0 0.0 6.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMR71485.1 - 6.8e-05 22.3 2.7 0.074 12.8 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR71485.1 - 0.0015 18.7 13.9 0.23 11.8 0.0 3.8 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMR71485.1 - 0.023 14.4 6.8 0.05 13.4 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Trehalase PF01204.13 EMR71485.1 - 0.029 12.9 0.1 0.047 12.3 0.1 1.3 1 0 0 1 1 1 0 Trehalase TPR_6 PF13174.1 EMR71485.1 - 0.09 13.2 5.7 2.5 8.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EMR71485.1 - 0.13 12.5 7.0 3.4 8.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 EMR71485.1 - 2 9.1 8.1 0.39 11.4 0.2 3.3 3 0 0 3 3 3 0 Sel1 repeat TPR_16 PF13432.1 EMR71485.1 - 2.2 9.0 25.8 1.5 9.5 1.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Glyoxalase_2 PF12681.2 EMR71486.1 - 4.5e-07 30.4 0.1 5.6e-07 30.1 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EMR71486.1 - 0.0029 17.6 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BTB PF00651.26 EMR71487.1 - 0.00011 22.1 0.0 0.00023 21.1 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain AAA_11 PF13086.1 EMR71487.1 - 0.046 13.2 0.0 0.055 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.22 EMR71488.1 - 3.1e-57 190.2 0.6 1.1e-18 66.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.16 EMR71489.1 - 2.1e-22 79.4 0.0 3.4e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EMR71489.1 - 8.1e-14 51.4 0.0 3.6e-10 39.6 0.0 3.8 2 2 0 2 2 2 2 Calpain large subunit, domain III MIT PF04212.13 EMR71489.1 - 0.007 16.2 2.8 0.012 15.4 2.0 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Methyltransf_2 PF00891.13 EMR71491.1 - 1.9e-36 125.4 0.0 2.5e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase RrnaAD PF00398.15 EMR71491.1 - 0.0056 15.7 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EMR71491.1 - 0.18 11.1 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain GMC_oxred_N PF00732.14 EMR71492.1 - 1.2e-25 90.3 0.0 1.9e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR71492.1 - 3.3e-23 82.5 0.2 7.6e-23 81.4 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMR71492.1 - 1.5e-09 37.2 0.3 0.00033 19.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain CBM_1 PF00734.13 EMR71492.1 - 4.4e-08 32.6 4.7 9.2e-08 31.6 3.2 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain DAO PF01266.19 EMR71492.1 - 1.3e-06 27.6 0.1 0.00015 20.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR71492.1 - 8.7e-05 22.4 0.3 0.00024 21.0 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR71492.1 - 0.00082 19.4 0.1 0.008 16.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR71492.1 - 0.0017 16.8 0.1 0.0028 16.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EMR71492.1 - 0.0061 15.6 0.0 0.35 9.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR71492.1 - 0.0086 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR71492.1 - 0.032 13.3 0.4 0.072 12.1 0.3 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EMR71492.1 - 0.042 12.9 0.1 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EMR71492.1 - 0.049 12.5 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GFA PF04828.9 EMR71493.1 - 1.5e-17 63.2 0.3 2.1e-17 62.8 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EMR71493.1 - 0.64 9.7 0.1 0.64 9.7 0.1 2.7 2 1 0 2 2 2 0 Nudix N-terminal zf-NADH-PPase PF09297.6 EMR71493.1 - 1.2 8.6 7.3 0.38 10.2 0.7 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain PAF-AH_p_II PF03403.8 EMR71495.1 - 3.1e-18 65.2 0.0 3.3e-09 35.5 0.0 2.1 1 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EMR71495.1 - 1.7e-15 57.0 0.1 2.4e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR71495.1 - 5.9e-10 39.4 0.2 7.3e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMR71495.1 - 2.6e-05 23.2 0.0 0.00021 20.2 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme CTP_transf_3 PF02348.14 EMR71495.1 - 0.011 15.4 0.2 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Hydrolase_4 PF12146.3 EMR71495.1 - 0.023 14.5 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase ACP PF06857.6 EMR71495.1 - 0.029 14.2 0.1 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) Abhydrolase_2 PF02230.11 EMR71495.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EMR71495.1 - 0.096 11.8 0.2 0.74 8.9 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF4350 PF14258.1 EMR71495.1 - 0.11 12.7 0.0 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) TBP PF00352.16 EMR71496.1 - 2.1e-64 212.8 0.0 5.3e-31 105.8 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EMR71496.1 - 0.0014 18.6 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Aminotran_5 PF00266.14 EMR71497.1 - 7.6e-19 67.6 0.0 1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V U-box PF04564.10 EMR71499.1 - 9.2e-21 73.5 0.3 2.5e-20 72.2 0.0 1.9 2 1 0 2 2 2 1 U-box domain TPR_11 PF13414.1 EMR71499.1 - 7.3e-18 63.9 3.5 1.2e-14 53.7 0.2 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EMR71499.1 - 1.3e-07 30.8 1.2 0.0031 17.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EMR71499.1 - 9.3e-07 28.3 4.0 0.38 10.7 0.2 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EMR71499.1 - 9.9e-06 25.4 2.5 0.00077 19.3 1.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EMR71499.1 - 0.0046 16.6 4.1 0.17 11.7 0.4 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2265 PF10023.4 EMR71499.1 - 0.011 14.8 0.7 0.023 13.8 0.5 1.5 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) TPR_17 PF13431.1 EMR71499.1 - 0.033 14.3 1.0 3.9 7.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EMR71499.1 - 0.047 13.8 3.2 0.087 12.9 0.9 2.3 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.2 EMR71499.1 - 0.08 12.7 0.1 0.21 11.3 0.1 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.1 EMR71499.1 - 0.22 11.4 1.4 1.8 8.5 0.1 2.9 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat DUF4404 PF14357.1 EMR71499.1 - 0.39 11.1 2.8 1.2 9.6 1.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Rho_Binding PF08912.6 EMR71499.1 - 0.73 10.1 4.8 0.83 9.9 2.0 2.1 2 0 0 2 2 2 0 Rho Binding WD40 PF00400.27 EMR71501.1 - 4.7e-19 67.4 5.2 0.00023 20.9 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Sec16_C PF12931.2 EMR71501.1 - 5.3e-05 23.0 0.0 0.00016 21.5 0.0 1.7 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 RRM_1 PF00076.17 EMR71502.1 - 1.6e-18 66.1 0.0 2.2e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR71502.1 - 1.6e-14 53.6 0.0 2.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR71502.1 - 5.9e-10 38.8 0.0 9.1e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2167 PF09935.4 EMR71502.1 - 0.07 11.9 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) RRM_3 PF08777.6 EMR71502.1 - 0.11 12.4 0.0 0.4 10.5 0.0 1.8 1 1 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.1 EMR71502.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4188 PF13826.1 EMR71503.1 - 1.4e-15 57.3 0.0 1.9e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 EMR71503.1 - 0.0059 15.7 0.0 0.0084 15.1 0.0 1.3 1 0 0 1 1 1 1 Haem-containing dehydratase DUF3291 PF11695.3 EMR71503.1 - 0.05 13.0 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) NAD_binding_4 PF07993.7 EMR71504.1 - 8e-19 67.5 0.0 4.3e-18 65.1 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EMR71504.1 - 9.3e-08 32.2 0.1 3e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EMR71504.1 - 1.1e-07 31.5 0.0 3.8e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMR71504.1 - 0.014 15.2 0.2 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EMR71504.1 - 0.047 13.3 0.1 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 KR domain NmrA PF05368.8 EMR71504.1 - 0.08 12.1 0.0 0.29 10.3 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family Myb_DNA-bind_6 PF13921.1 EMR71505.1 - 4.6e-34 116.3 19.1 3.8e-16 58.9 0.3 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMR71505.1 - 5.3e-34 116.0 13.0 1.6e-13 50.4 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain DUF2508 PF10704.4 EMR71505.1 - 0.11 12.6 0.2 11 6.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Myb_DNA-bind_5 PF13873.1 EMR71505.1 - 0.34 10.8 17.1 36 4.3 3.7 5.5 3 2 2 5 5 5 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EMR71505.1 - 2.2 8.4 18.7 5.1 7.2 2.5 4.2 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 EMR71505.1 - 4.7 7.1 12.1 27 4.7 1.4 3.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Translin PF01997.11 EMR71506.1 - 3.7e-44 150.7 0.0 5.2e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Translin family Syntaxin PF00804.20 EMR71506.1 - 0.031 14.4 0.2 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 Syntaxin DUF3450 PF11932.3 EMR71506.1 - 0.038 13.2 0.9 0.055 12.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_13 PF13166.1 EMR71506.1 - 0.16 10.3 0.1 0.2 10.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain KIX PF02172.11 EMR71506.1 - 0.22 11.5 2.5 0.35 10.9 0.6 2.1 2 1 0 2 2 2 0 KIX domain CCER1 PF15482.1 EMR71507.1 - 0.015 14.9 4.0 0.02 14.5 2.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 SelP_N PF04592.9 EMR71507.1 - 1.5 8.1 4.9 2 7.7 3.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Mannosyl_trans PF05007.8 EMR71508.1 - 2.9e-75 253.2 1.7 3.7e-62 210.2 1.3 2.1 2 0 0 2 2 2 2 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EMR71508.1 - 4e-15 55.5 5.4 4.6e-15 55.3 0.0 2.3 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U Serglycin PF04360.7 EMR71508.1 - 0.076 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Serglycin DUF3619 PF12279.3 EMR71508.1 - 0.1 12.6 0.1 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) NMT1 PF09084.6 EMR71509.1 - 1.6e-76 256.6 0.0 2.1e-76 256.2 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EMR71509.1 - 1.7e-08 34.1 0.5 0.035 13.4 0.1 3.3 2 1 0 3 3 3 3 NMT1-like family Phosphonate-bd PF12974.2 EMR71509.1 - 0.042 13.2 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein HET PF06985.6 EMR71510.1 - 9.7e-15 54.9 0.0 1.5e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M28 PF04389.12 EMR71511.1 - 6.2e-29 100.9 0.6 9.9e-29 100.3 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EMR71511.1 - 0.0026 17.2 0.2 0.0041 16.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ING PF12998.2 EMR71513.1 - 1.3e-21 76.8 2.5 2e-21 76.2 1.7 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EMR71513.1 - 1e-08 34.7 8.9 2e-08 33.7 6.2 1.5 1 0 0 1 1 1 1 PHD-finger Zip PF02535.17 EMR71513.1 - 0.017 14.1 5.2 0.02 13.8 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EMR71513.1 - 1.4 8.2 12.9 2.3 7.5 8.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BAF1_ABF1 PF04684.8 EMR71513.1 - 4.4 6.0 20.0 8.1 5.1 13.8 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor UDPGP PF01704.13 EMR71514.1 - 9.7e-185 614.0 0.3 1.1e-184 613.8 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 EMR71514.1 - 0.039 12.5 0.2 0.14 10.7 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4301) Hist_deacetyl PF00850.14 EMR71515.1 - 1.4e-79 267.6 0.0 2.3e-79 266.9 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain DUF3605 PF12239.3 EMR71516.1 - 2e-56 190.2 0.9 2.4e-56 189.9 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FolB PF02152.13 EMR71517.1 - 6.8e-07 29.4 0.0 8.3e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase Peptidase_M28 PF04389.12 EMR71518.1 - 2.9e-33 115.1 0.0 4.8e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMR71518.1 - 1.3e-12 47.2 0.1 2.3e-11 43.2 0.0 2.5 2 0 0 2 2 2 1 PA domain ATP_bind_4 PF01902.12 EMR71519.1 - 5.1e-16 58.6 0.0 3.8e-05 23.1 0.0 3.8 4 0 0 4 4 4 3 ATP-binding region Ribonuc_L-PSP PF01042.16 EMR71519.1 - 2.5e-11 43.3 0.2 1.4e-06 28.1 0.0 3.9 4 0 0 4 4 4 2 Endoribonuclease L-PSP zf-C2H2 PF00096.21 EMR71520.1 - 1.4e-11 44.0 14.8 1.2e-06 28.4 0.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR71520.1 - 1.9e-10 40.3 13.0 0.00013 22.0 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMR71520.1 - 3.3e-08 33.4 17.9 2.5e-07 30.6 3.3 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 EMR71520.1 - 0.00028 20.9 7.8 0.0049 17.0 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EMR71520.1 - 0.00079 19.5 7.1 0.019 15.0 0.8 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EMR71520.1 - 0.0077 16.0 0.8 0.0077 16.0 0.5 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger TFIIS_C PF01096.13 EMR71520.1 - 0.059 13.0 1.7 7.6 6.2 0.0 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 EMR71520.1 - 0.13 12.1 4.2 0.31 10.8 2.9 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-DNL PF05180.7 EMR71520.1 - 0.15 11.7 2.4 2.1 8.1 0.1 2.4 2 0 0 2 2 2 0 DNL zinc finger PcfK PF14058.1 EMR71520.1 - 0.23 11.5 5.5 0.48 10.5 3.8 1.4 1 0 0 1 1 1 0 PcfK-like protein Elf1 PF05129.8 EMR71520.1 - 0.35 10.6 5.0 5.8 6.6 3.5 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 EMR71520.1 - 0.5 10.1 9.1 0.11 12.2 2.0 2.4 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.2 EMR71520.1 - 0.66 10.1 5.6 9.3 6.4 0.3 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) LIM PF00412.17 EMR71520.1 - 1.1 9.4 6.8 1.1 9.3 3.6 2.0 2 0 0 2 2 2 0 LIM domain Zn-ribbon_8 PF09723.5 EMR71520.1 - 1.1 9.2 5.4 3.5 7.6 0.4 2.6 1 1 1 2 2 2 0 Zinc ribbon domain PAP2 PF01569.16 EMR71521.1 - 0.012 15.3 0.1 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 PAP2 superfamily Mito_fiss_reg PF05308.6 EMR71521.1 - 0.56 9.5 8.1 0.77 9.0 5.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator TMEM171 PF15471.1 EMR71521.1 - 1.9 7.1 4.6 2.8 6.6 3.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 adh_short_C2 PF13561.1 EMR71522.1 - 0.04 13.6 0.0 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Musclin PF11037.3 EMR71522.1 - 0.053 13.1 0.0 0.067 12.8 0.0 1.1 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle Aldedh PF00171.17 EMR71523.1 - 2.9e-138 461.1 0.0 3.3e-138 460.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMR71523.1 - 0.0097 14.6 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Aminotran_1_2 PF00155.16 EMR71524.1 - 1.3e-29 103.3 0.0 1.7e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EMR71524.1 - 8.6e-06 24.2 0.0 1.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EMR71524.1 - 0.00015 21.0 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EMR71524.1 - 0.0067 15.5 0.5 0.039 12.9 0.0 2.2 2 1 1 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family zf-C2H2_4 PF13894.1 EMR71525.1 - 0.0036 17.5 16.2 0.53 10.7 1.8 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EMR71525.1 - 0.021 15.1 3.1 0.021 15.1 2.2 3.7 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EMR71525.1 - 0.14 12.3 8.3 0.5 10.5 1.5 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EMR71525.1 - 0.41 11.0 20.4 0.27 11.6 0.5 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EMR71525.1 - 5.2 7.2 8.2 54 3.9 0.8 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) WD40 PF00400.27 EMR71527.1 - 1.1e-11 44.0 0.7 0.00048 19.9 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 EMR71527.1 - 0.05 12.6 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RNA_pol_N PF01194.12 EMR71528.1 - 3.6e-29 100.5 0.7 4.2e-29 100.3 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Tad PF13400.1 EMR71529.1 - 0.014 15.4 0.5 0.019 14.9 0.3 1.2 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like PLDc_2 PF13091.1 EMR71530.1 - 5.2e-13 48.8 0.0 4.1e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EMR71530.1 - 4.1e-07 29.5 3.9 0.03 14.1 0.3 3.7 3 1 0 3 3 3 2 Phospholipase D Active site motif Ank_2 PF12796.2 EMR71531.1 - 3.7e-24 84.8 8.8 6.1e-13 48.9 0.2 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMR71531.1 - 7.1e-19 67.8 5.4 2e-10 40.8 0.2 3.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EMR71531.1 - 1.5e-17 62.4 3.1 5e-10 38.6 0.2 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EMR71531.1 - 7.5e-14 51.4 1.1 6.4e-09 35.7 0.2 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR71531.1 - 5.5e-13 47.7 1.0 8.1e-07 28.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat DUF1110 PF06533.7 EMR71531.1 - 0.013 15.2 1.4 0.023 14.4 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1110) SYF2 PF08231.7 EMR71531.1 - 0.032 14.3 0.0 0.042 13.9 0.0 1.2 1 0 0 1 1 1 0 SYF2 splicing factor PALP PF00291.20 EMR71532.1 - 7.8e-22 77.8 0.0 9.6e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HTH_19 PF12844.2 EMR71532.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain GST_N_3 PF13417.1 EMR71533.1 - 2.2e-25 88.6 0.0 4.5e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMR71533.1 - 5.4e-19 67.9 0.1 1.9e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR71533.1 - 5.1e-10 39.1 0.1 1e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMR71533.1 - 6.2e-06 26.2 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR71533.1 - 2.5e-05 24.1 0.0 5.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR71533.1 - 0.013 15.9 0.1 0.032 14.7 0.0 1.7 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Clr5 PF14420.1 EMR71534.1 - 3.4e-20 71.6 6.6 4.9e-20 71.1 4.6 1.3 1 0 0 1 1 1 1 Clr5 domain Tox-REase-7 PF15649.1 EMR71534.1 - 0.0089 16.1 0.4 0.021 14.9 0.0 1.7 2 1 0 2 2 2 1 Restriction endonuclease fold toxin 7 His_Phos_1 PF00300.17 EMR71534.1 - 0.16 12.0 1.6 0.17 11.9 1.1 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) NDUFA12 PF05071.11 EMR71535.1 - 8.8e-26 90.4 2.6 1.1e-25 90.1 1.8 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 WHIM2 PF15613.1 EMR71535.1 - 0.043 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 LCCL PF03815.14 EMR71536.1 - 3.9e-22 78.0 0.2 3.9e-22 78.0 0.2 1.6 2 0 0 2 2 2 1 LCCL domain MIP-T3 PF10243.4 EMR71537.1 - 3 6.2 16.6 3.6 5.9 11.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Peptidase_M20 PF01546.23 EMR71538.1 - 2.1e-20 73.0 0.1 3.3e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EMR71538.1 - 1e-18 67.1 0.0 2.1e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain PALP PF00291.20 EMR71538.1 - 5.1e-08 32.5 1.1 5.2e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme TGT PF01702.13 EMR71539.1 - 1e-21 77.3 0.1 1.2e-21 77.0 0.1 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF1470 PF07336.6 EMR71540.1 - 0.062 13.6 5.2 0.058 13.7 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1470) MAD PF05557.8 EMR71540.1 - 0.12 10.4 0.0 0.18 9.8 0.0 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein Glycolipid_bind PF06475.6 EMR71542.1 - 0.065 12.3 0.1 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative glycolipid-binding Aldedh PF00171.17 EMR71543.1 - 3.5e-177 589.3 1.0 3.9e-177 589.2 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HsbA PF12296.3 EMR71544.1 - 0.00019 21.3 2.1 0.00019 21.3 1.4 2.2 2 1 0 2 2 2 1 Hydrophobic surface binding protein A SET PF00856.23 EMR71545.1 - 2e-11 44.4 0.0 8.5e-11 42.4 0.0 2.0 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 EMR71545.1 - 4.1e-05 23.4 0.0 9.4e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding KGG PF10685.4 EMR71547.1 - 9.8e-38 127.3 24.4 3.1e-11 42.8 0.2 4.2 4 0 0 4 4 4 4 Stress-induced bacterial acidophilic repeat motif LEA_5 PF00477.12 EMR71547.1 - 0.23 11.7 5.4 0.45 10.8 3.7 1.7 1 1 0 1 1 1 0 Small hydrophilic plant seed protein IPP-2 PF04979.9 EMR71548.1 - 4.5e-09 36.6 12.8 2.9e-07 30.8 8.9 2.3 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) UvdE PF03851.9 EMR71549.1 - 3.7e-107 357.4 0.0 5.3e-107 356.9 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF3716 PF12511.3 EMR71550.1 - 2e-06 27.3 0.3 3.4e-06 26.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF2076 PF09849.4 EMR71551.1 - 0.0032 17.5 0.1 0.0032 17.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Ribosomal_L27 PF01016.14 EMR71552.1 - 2.1e-25 88.3 0.1 4e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein DUF3987 PF13148.1 EMR71552.1 - 0.34 9.4 7.4 0.49 8.9 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) PBP_sp32 PF07222.7 EMR71552.1 - 0.39 9.8 2.5 0.51 9.4 1.7 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Alk_phosphatase PF00245.15 EMR71553.1 - 6.4e-63 212.9 0.0 9.8e-63 212.2 0.0 1.3 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 EMR71553.1 - 1.3e-05 24.7 0.9 1.3e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EMR71553.1 - 1.7e-05 24.1 0.1 3.7e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EMR71553.1 - 0.0019 16.7 0.2 0.0029 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 EMR71553.1 - 0.056 12.2 0.1 0.085 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Bac_rhamnosid PF05592.6 EMR71554.1 - 6.2e-08 31.3 0.5 6.1e-06 24.7 0.1 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase p450 PF00067.17 EMR71555.1 - 0.0024 16.4 0.0 0.0026 16.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transketolase_C PF02780.15 EMR71555.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 Transketolase, C-terminal domain Abhydrolase_2 PF02230.11 EMR71556.1 - 1.2e-15 57.5 0.0 3.9e-14 52.6 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EMR71556.1 - 5.5e-07 29.4 0.0 8.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR71556.1 - 3.9e-06 26.9 0.0 0.0001 22.2 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 EMR71556.1 - 0.0012 18.3 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 EMR71556.1 - 0.055 13.3 0.0 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 EMR71556.1 - 0.098 12.2 0.0 0.28 10.7 0.0 1.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold Sugar_tr PF00083.19 EMR71557.1 - 2.6e-121 405.3 29.9 3e-121 405.1 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR71557.1 - 8.2e-20 70.8 40.4 3.2e-12 45.8 14.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMR71557.1 - 0.1 12.4 9.6 0.51 10.1 0.1 3.8 3 0 0 3 3 3 0 MFS_1 like family EHN PF06441.7 EMR71558.1 - 1.8e-19 69.7 0.1 4.1e-19 68.5 0.1 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus ABC_tran PF00005.22 EMR71559.1 - 7.1e-35 120.2 0.0 1e-16 61.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMR71559.1 - 6.9e-24 84.7 33.2 7.2e-23 81.3 7.2 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EMR71559.1 - 8.4e-06 25.1 0.8 0.039 13.1 0.2 3.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMR71559.1 - 1.3e-05 25.2 0.0 0.024 14.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EMR71559.1 - 1.8e-05 24.7 0.5 0.075 13.0 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EMR71559.1 - 1.8e-05 24.8 0.1 0.37 10.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EMR71559.1 - 5.7e-05 22.6 1.6 0.076 12.4 0.1 3.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EMR71559.1 - 0.00034 20.0 0.5 0.48 9.9 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EMR71559.1 - 0.00053 19.5 0.3 0.32 10.4 0.0 2.7 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 EMR71559.1 - 0.0013 17.9 0.1 0.6 9.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EMR71559.1 - 0.0019 17.7 0.8 1.1 8.6 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain Miro PF08477.8 EMR71559.1 - 0.0027 18.1 0.1 1.2 9.6 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EMR71559.1 - 0.0073 16.2 0.0 2.6 8.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.4 EMR71559.1 - 0.0092 14.6 1.5 0.25 9.8 0.1 2.7 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.8 EMR71559.1 - 0.021 13.7 0.1 0.088 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.18 EMR71559.1 - 0.039 13.7 0.1 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.7 EMR71559.1 - 0.049 12.7 0.3 0.46 9.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 EMR71559.1 - 0.068 13.3 0.0 0.95 9.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EMR71559.1 - 0.11 12.4 0.2 10 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain Hid1 PF12722.2 EMR71560.1 - 1.3e-165 552.5 0.1 1e-85 288.2 0.0 3.8 1 1 2 3 3 3 3 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EMR71560.1 - 1e-35 123.0 0.0 1.9e-21 75.8 0.0 2.9 1 1 2 3 3 3 3 Dyggve-Melchior-Clausen syndrome protein MFS_1 PF07690.11 EMR71561.1 - 9.9e-26 90.2 73.3 4.8e-18 64.9 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EMR71561.1 - 4.9e-06 26.4 8.1 0.079 12.9 0.3 3.7 3 1 0 3 3 3 3 Protein of unknown function (DUF1228) IF4E PF01652.13 EMR71562.1 - 1.3e-38 132.1 0.4 1.6e-38 131.8 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Sec8_exocyst PF04048.9 EMR71563.1 - 1.3e-49 167.4 1.7 4.1e-49 165.8 1.2 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EMR71563.1 - 1.9e-12 46.7 1.4 3.6e-12 45.7 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Phage_GP20 PF06810.6 EMR71563.1 - 0.058 12.8 0.5 0.22 10.9 0.3 2.0 1 0 0 1 1 1 0 Phage minor structural protein GP20 Pkinase PF00069.20 EMR71564.1 - 1.3e-67 227.7 0.0 1.9e-67 227.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR71564.1 - 1.1e-48 165.5 0.0 1.7e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR71564.1 - 5.3e-06 25.5 0.0 1.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like ACT_3 PF10000.4 EMR71564.1 - 0.093 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 ACT domain Clr5 PF14420.1 EMR71565.1 - 1.7e-11 43.8 0.7 3.2e-11 42.9 0.2 1.7 2 0 0 2 2 2 1 Clr5 domain TPR_2 PF07719.12 EMR71566.1 - 4.6e-29 97.9 18.5 4.6e-05 23.0 0.0 8.6 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_1 PF00515.23 EMR71566.1 - 1.4e-26 90.8 14.0 1.5e-05 24.4 0.4 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 EMR71566.1 - 1.8e-24 85.1 17.2 4.3e-08 32.6 0.0 5.8 6 0 0 6 6 5 5 TPR repeat TPR_12 PF13424.1 EMR71566.1 - 3.6e-21 74.8 17.1 2.9e-09 36.7 0.8 7.3 4 1 2 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EMR71566.1 - 1.8e-16 58.6 1.1 0.0032 17.1 0.1 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMR71566.1 - 6.5e-16 57.4 23.2 9e-05 22.7 0.0 7.9 5 2 3 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMR71566.1 - 8e-16 58.2 27.7 1.5e-08 35.0 1.7 7.1 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EMR71566.1 - 1.9e-15 56.9 12.8 0.00037 20.7 0.1 6.8 5 2 2 8 8 8 5 Tetratricopeptide repeat TPR_10 PF13374.1 EMR71566.1 - 2.5e-13 49.4 13.5 0.0013 18.5 1.0 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EMR71566.1 - 4.7e-11 41.6 17.3 0.015 15.0 0.0 6.9 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.1 EMR71566.1 - 1.3e-07 31.4 14.0 0.00016 21.4 1.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EMR71566.1 - 8.1e-06 25.8 11.3 0.32 11.1 0.0 5.7 4 2 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EMR71566.1 - 9.6e-06 25.4 5.0 5 7.5 0.0 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 EMR71566.1 - 1.2e-05 24.5 5.6 0.007 15.4 0.0 4.2 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EMR71566.1 - 6.5e-05 23.1 17.6 0.28 11.7 0.1 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat PPR PF01535.15 EMR71566.1 - 0.00036 20.3 0.3 1.2 9.2 0.0 4.6 5 0 0 5 5 4 1 PPR repeat Coatomer_E PF04733.9 EMR71566.1 - 0.0026 17.0 0.1 2.1 7.4 0.0 3.4 3 2 0 4 4 4 1 Coatomer epsilon subunit TPR_4 PF07721.9 EMR71566.1 - 0.0085 16.4 15.2 1.7 9.2 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.13 EMR71566.1 - 0.061 13.2 0.8 31 4.5 0.0 4.0 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 EMR71566.1 - 0.11 12.6 6.6 6.9 6.8 0.3 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 EMR71566.1 - 6.9 6.6 11.5 23 4.8 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.1 EMR71566.1 - 8.4 5.4 11.9 3.5 6.6 0.0 4.0 4 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP Transglut_core PF01841.14 EMR71567.1 - 6.2e-12 45.7 0.4 1.6e-11 44.4 0.3 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Abhydrolase_6 PF12697.2 EMR71568.1 - 5.1e-25 88.7 1.1 5.8e-25 88.5 0.7 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR71568.1 - 1.9e-10 40.7 0.0 2.7e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EMR71568.1 - 0.0005 18.9 0.0 0.00077 18.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 EMR71568.1 - 0.00065 18.6 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF3220 PF11516.3 EMR71568.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) PAT1 PF09770.4 EMR71569.1 - 9.7 4.2 63.5 14 3.7 44.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Myosin_head PF00063.16 EMR71570.1 - 9.8e-232 770.8 3.8 1.5e-231 770.2 2.7 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EMR71570.1 - 2.3e-38 131.5 0.0 5.5e-38 130.2 0.0 1.7 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 EMR71570.1 - 1.3e-12 46.9 0.2 2.4e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EMR71570.1 - 7.7e-10 38.2 0.1 1.7e-09 37.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EMR71570.1 - 8.2e-09 34.8 0.1 1.9e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.22 EMR71570.1 - 0.0014 18.1 9.7 0.04 13.5 1.7 2.8 1 1 1 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 EMR71570.1 - 0.0061 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Hpr_kinase_C PF07475.7 EMR71570.1 - 0.0091 15.3 0.4 2.8 7.2 0.0 2.3 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 EMR71570.1 - 0.023 13.8 0.0 0.056 12.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF552 PF04472.7 EMR71570.1 - 0.045 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF552) AAA_17 PF13207.1 EMR71570.1 - 0.069 13.9 0.0 0.21 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EMR71570.1 - 0.077 13.3 0.3 0.64 10.3 0.0 2.6 3 0 0 3 3 3 0 ABC transporter AAA_18 PF13238.1 EMR71570.1 - 0.11 12.7 0.1 0.34 11.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 EMR71570.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 EMR71570.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI zf-DHHC PF01529.15 EMR71573.1 - 2.6e-32 111.5 0.1 1.1e-31 109.6 0.1 1.9 1 1 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 EMR71573.1 - 0.25 11.1 3.6 0.67 9.7 2.5 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily DZR PF12773.2 EMR71573.1 - 1.6 8.5 9.8 2.8 7.8 6.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon RTA1 PF04479.8 EMR71574.1 - 2.9e-56 190.5 8.1 2.9e-56 190.5 5.6 1.6 2 0 0 2 2 2 1 RTA1 like protein DUF423 PF04241.10 EMR71574.1 - 0.46 10.4 4.3 0.51 10.2 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF423) CN_hydrolase PF00795.17 EMR71576.1 - 1.2e-30 106.2 0.1 1.9e-30 105.6 0.1 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FAD_binding_8 PF08022.7 EMR71577.1 - 3.3e-22 78.3 0.0 6.2e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EMR71577.1 - 9.1e-22 77.6 0.0 1.5e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMR71577.1 - 2.8e-08 33.8 8.0 8.3e-07 29.1 5.6 2.7 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EMR71577.1 - 0.00021 21.3 0.0 0.00052 20.0 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain LrgA PF03788.9 EMR71577.1 - 0.036 13.7 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 LrgA family NAD_binding_1 PF00175.16 EMR71577.1 - 0.051 14.1 0.0 3 8.4 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain RRM_1 PF00076.17 EMR71578.1 - 7.1e-13 47.9 0.0 1.1e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR71578.1 - 1.6e-09 37.5 0.0 2.5e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR71578.1 - 2.3e-06 27.3 0.0 3.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amidase PF01425.16 EMR71579.1 - 5.7e-66 223.1 0.2 1.9e-51 175.3 0.1 2.3 2 1 0 2 2 2 2 Amidase RdRP PF05183.7 EMR71580.1 - 9.1e-103 344.9 0.0 1.1e-102 344.6 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase Ferric_reduct PF01794.14 EMR71582.1 - 1.5e-16 60.6 19.8 9.2e-16 58.0 13.7 2.3 1 1 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EMR71582.1 - 4.2e-08 33.7 0.0 7.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EMR71582.1 - 5.1e-06 26.4 0.2 0.019 14.8 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMR71582.1 - 1.6e-05 24.7 0.0 0.016 15.0 0.0 2.7 2 0 0 2 2 2 2 FAD-binding domain Bac_rhodopsin PF01036.13 EMR71583.1 - 3.1e-15 56.0 7.9 3.7e-15 55.8 5.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF2069 PF09842.4 EMR71583.1 - 0.013 15.4 0.6 0.027 14.4 0.1 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2069) AIG2_2 PF13772.1 EMR71584.1 - 2.8e-08 33.7 0.0 4.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 EMR71584.1 - 5.1e-06 26.9 0.0 6.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family DDE_Tnp_Tn3 PF01526.12 EMR71584.1 - 0.11 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Tn3 transposase DDE domain FAD_binding_3 PF01494.14 EMR71585.1 - 4.7e-09 35.7 1.3 3.2e-06 26.4 0.0 2.5 2 1 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EMR71585.1 - 6.6e-07 29.2 0.0 1.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR71585.1 - 9.1e-05 21.5 0.2 0.00029 19.8 0.0 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EMR71585.1 - 0.00029 21.1 0.1 0.0011 19.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR71585.1 - 0.00095 19.0 0.1 0.0014 18.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR71585.1 - 0.0019 17.1 0.1 0.0027 16.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 EMR71585.1 - 0.0079 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 EMR71585.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EMR71585.1 - 0.049 12.6 0.2 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 EMR71585.1 - 0.057 13.5 0.1 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EMR71585.1 - 0.065 13.2 0.0 0.1 12.5 0.0 1.4 1 1 0 1 1 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EMR71585.1 - 0.098 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 EMR71585.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Ank PF00023.25 EMR71586.1 - 3.3e-11 42.4 0.0 0.01 15.6 0.0 4.7 4 1 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EMR71586.1 - 2.6e-10 40.5 0.0 7.5e-05 22.9 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EMR71586.1 - 6.8e-10 38.2 0.0 0.055 13.7 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EMR71586.1 - 4.9e-05 23.7 0.0 1.8 9.2 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR71586.1 - 0.0021 18.2 0.5 3 8.2 0.0 3.8 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.2 EMR71587.1 - 3.8e-24 85.8 0.1 6e-24 85.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_23 PF13489.1 EMR71587.1 - 1.7e-16 60.3 0.0 2.8e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMR71587.1 - 7.2e-12 44.9 0.0 1.3e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Abhydrolase_5 PF12695.2 EMR71587.1 - 1.9e-08 34.1 0.1 3.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_11 PF08241.7 EMR71587.1 - 2.1e-08 34.5 0.0 2.7e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EMR71587.1 - 3.1e-07 30.7 0.0 5.9e-06 26.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR71587.1 - 1e-06 28.3 0.0 5.4e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR71587.1 - 1.4e-06 28.8 0.0 3.6e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR71587.1 - 2e-05 24.9 0.0 6.5e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR71587.1 - 0.00012 22.1 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Abhydrolase_1 PF00561.15 EMR71587.1 - 0.00048 19.7 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold MetW PF07021.7 EMR71587.1 - 0.0042 16.4 0.2 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW MTS PF05175.9 EMR71587.1 - 0.0055 16.0 0.0 0.0097 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Chlorophyllase2 PF12740.2 EMR71587.1 - 0.0056 15.5 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme PCMT PF01135.14 EMR71587.1 - 0.016 14.7 0.1 0.037 13.5 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Chlorophyllase PF07224.6 EMR71587.1 - 0.067 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DOT1 PF08123.8 EMR71587.1 - 0.2 10.9 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 TehB PF03848.9 EMR71587.1 - 0.22 10.6 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_11 PF08241.7 EMR71588.1 - 1.9e-21 76.3 0.0 4e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR71588.1 - 5e-15 55.3 0.0 7.9e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR71588.1 - 9.1e-15 54.7 0.0 1.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR71588.1 - 2.5e-12 47.1 0.0 4.7e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR71588.1 - 1.2e-11 44.8 0.0 2.2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR71588.1 - 7.1e-11 41.6 0.0 1.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EMR71588.1 - 8.8e-10 38.1 0.0 1.2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EMR71588.1 - 6.2e-09 36.4 0.0 1.2e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR71588.1 - 1.4e-06 28.3 0.2 1.4e-05 25.1 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EMR71588.1 - 5.3e-05 22.6 0.0 9.7e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EMR71588.1 - 0.00038 19.8 0.0 0.00063 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EMR71588.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EMR71588.1 - 0.0018 17.9 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EMR71588.1 - 0.0099 14.9 0.1 0.022 13.8 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase FmrO PF07091.6 EMR71588.1 - 0.025 13.5 0.0 0.055 12.4 0.0 1.4 1 1 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TehB PF03848.9 EMR71588.1 - 0.047 12.8 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_9 PF08003.6 EMR71588.1 - 0.06 12.0 0.0 0.16 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.13 EMR71588.1 - 0.062 12.4 0.0 0.28 10.3 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase DREV PF05219.7 EMR71588.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase PrmA PF06325.8 EMR71588.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HTH_8 PF02954.14 EMR71589.1 - 0.069 12.6 0.3 0.17 11.4 0.2 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Pex14_N PF04695.8 EMR71590.1 - 0.045 13.7 1.6 0.057 13.4 1.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3953 PF13129.1 EMR71591.1 - 0.016 14.8 0.8 0.35 10.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) APH PF01636.18 EMR71592.1 - 0.0005 19.8 0.5 0.0066 16.2 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family LAT PF15234.1 EMR71592.1 - 0.041 13.3 6.4 0.9 8.9 1.4 2.5 2 0 0 2 2 2 0 Linker for activation of T-cells PBP1_TM PF14812.1 EMR71592.1 - 0.046 14.0 20.6 0.88 9.9 5.7 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RIO1 PF01163.17 EMR71592.1 - 0.095 12.0 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.15 EMR71592.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Nucleoplasmin PF03066.10 EMR71592.1 - 6.7 6.2 17.8 0.14 11.6 1.4 2.6 3 0 0 3 3 3 0 Nucleoplasmin MFS_1 PF07690.11 EMR71594.1 - 2.8e-05 23.0 6.3 3.7e-05 22.6 4.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC_tran PF00005.22 EMR71595.1 - 2.6e-46 157.3 0.0 1.7e-25 89.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMR71595.1 - 2.8e-19 69.5 11.8 4.8e-14 52.4 1.6 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EMR71595.1 - 3.9e-11 42.5 1.3 0.00049 19.3 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMR71595.1 - 5.8e-08 33.0 1.5 0.024 14.5 0.0 4.0 3 1 0 4 4 4 2 AAA domain T2SE PF00437.15 EMR71595.1 - 6.6e-06 25.2 0.8 0.03 13.2 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 EMR71595.1 - 2e-05 24.6 0.1 0.29 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 EMR71595.1 - 2.9e-05 23.6 0.9 0.037 13.4 0.0 3.1 3 0 0 3 3 3 1 AAA-like domain AAA_29 PF13555.1 EMR71595.1 - 4.6e-05 22.8 1.2 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.1 EMR71595.1 - 0.00035 20.4 0.4 0.014 15.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EMR71595.1 - 0.00051 19.9 0.0 0.91 9.5 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EMR71595.1 - 0.00053 19.4 0.3 0.62 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMR71595.1 - 0.00058 19.9 2.0 0.083 13.0 0.0 3.6 4 0 0 4 4 3 1 AAA domain DUF258 PF03193.11 EMR71595.1 - 0.00085 18.5 2.1 0.014 14.6 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 EMR71595.1 - 0.0017 18.5 0.3 0.48 10.6 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EMR71595.1 - 0.004 17.5 1.0 0.29 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EMR71595.1 - 0.0054 17.5 0.7 2.3 9.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMR71595.1 - 0.0063 16.8 0.0 5.5 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMR71595.1 - 0.0065 16.0 1.0 4.5 6.8 0.0 4.1 4 1 0 4 4 4 0 AAA domain Miro PF08477.8 EMR71595.1 - 0.01 16.3 0.5 2.5 8.6 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Spore_IV_A PF09547.5 EMR71595.1 - 0.02 13.6 0.3 0.053 12.2 0.0 1.7 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) DUF87 PF01935.12 EMR71595.1 - 0.021 14.6 1.3 0.067 13.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 EMR71595.1 - 0.022 14.4 1.0 2.3 7.9 0.2 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EMR71595.1 - 0.024 13.7 0.4 2.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 EMR71595.1 - 0.036 13.7 0.1 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EMR71595.1 - 0.064 12.7 0.6 1.2 8.5 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AIG1 PF04548.11 EMR71595.1 - 0.095 11.7 3.5 4.1 6.4 0.2 2.8 3 0 0 3 3 3 0 AIG1 family AAA_14 PF13173.1 EMR71595.1 - 0.099 12.5 0.1 0.69 9.8 0.0 2.6 4 0 0 4 4 1 0 AAA domain Viral_helicase1 PF01443.13 EMR71595.1 - 0.11 11.9 0.5 2.4 7.6 0.1 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.4 EMR71595.1 - 0.12 11.0 1.1 7 5.1 0.2 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 EMR71595.1 - 0.13 11.8 0.0 6.1 6.2 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 EMR71595.1 - 0.14 12.3 0.1 6 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase HXXEE PF13787.1 EMR71595.1 - 0.14 12.5 0.2 0.14 12.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif Adeno_IVa2 PF02456.10 EMR71595.1 - 0.14 10.7 0.0 0.28 9.8 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein Dynamin_N PF00350.18 EMR71595.1 - 0.15 11.8 2.4 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Dynamin family Zot PF05707.7 EMR71595.1 - 0.16 11.4 0.1 2.5 7.5 0.0 2.7 2 1 2 4 4 3 0 Zonular occludens toxin (Zot) ATP-synt_ab PF00006.20 EMR71595.1 - 0.28 10.6 3.9 2.8 7.3 0.1 3.5 5 0 0 5 5 4 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 EMR71595.1 - 0.5 9.7 2.7 0.42 10.0 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HET PF06985.6 EMR71596.1 - 5.2e-21 75.2 5.0 1.8e-20 73.4 1.4 2.7 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.14 EMR71599.1 - 9.6e-36 123.4 0.0 1.5e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR71599.1 - 8.8e-29 100.6 0.0 1.7e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase adh_short_C2 PF13561.1 EMR71601.1 - 3.7e-25 89.0 0.0 5.1e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR71601.1 - 5e-23 81.8 0.5 6.2e-23 81.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR71601.1 - 1.1e-09 38.2 0.2 1.4e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR71601.1 - 0.0071 16.3 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding DFP PF04127.10 EMR71601.1 - 0.072 12.7 1.6 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.14 EMR71601.1 - 0.094 11.7 0.1 3.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EMR71601.1 - 0.38 10.3 1.7 0.37 10.4 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Malectin_like PF12819.2 EMR71602.1 - 0.039 13.0 0.4 0.05 12.6 0.3 1.1 1 0 0 1 1 1 0 Carbohydrate-binding protein of the ER BTB PF00651.26 EMR71603.1 - 5e-06 26.4 0.0 1.4e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain MazG PF03819.12 EMR71603.1 - 0.04 13.8 0.1 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain GATase_2 PF00310.16 EMR71604.1 - 2.8e-19 69.0 0.0 9.5e-15 54.1 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EMR71604.1 - 4.1e-14 52.6 0.0 1.2e-13 51.2 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EMR71604.1 - 2.3e-13 49.9 0.0 4.6e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EMR71604.1 - 5.9e-11 42.1 0.1 1.2e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EMR71604.1 - 1.8e-05 23.5 0.0 3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II zf-C3HC4_2 PF13923.1 EMR71605.1 - 0.002 18.1 6.7 0.0058 16.6 4.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMR71605.1 - 0.0036 16.9 6.7 0.0091 15.6 4.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EMR71605.1 - 0.011 15.5 8.0 0.033 14.0 4.5 2.3 2 0 0 2 2 2 0 Ring finger domain DUF2407 PF10302.4 EMR71605.1 - 0.019 15.1 0.1 0.25 11.5 0.0 2.3 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain zf-RING_5 PF14634.1 EMR71605.1 - 0.25 11.0 4.7 0.66 9.7 3.3 1.8 1 0 0 1 1 1 0 zinc-RING finger domain DUF1272 PF06906.6 EMR71605.1 - 1.2 9.0 8.1 3.7 7.4 5.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Glutaredoxin PF00462.19 EMR71607.1 - 1.4e-13 50.6 0.0 3e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EMR71607.1 - 0.0087 16.2 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_L2_C PF03947.13 EMR71607.1 - 0.076 12.8 0.7 0.16 11.8 0.5 1.5 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain DNA_pol_phi PF04931.8 EMR71607.1 - 0.95 7.1 5.2 1.3 6.7 3.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ribonuclease_3 PF00636.21 EMR71608.1 - 3.4e-42 143.4 0.0 3.6e-22 78.9 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EMR71608.1 - 3.4e-29 101.3 0.0 3.3e-13 49.6 0.0 3.6 2 2 0 2 2 2 2 Ribonuclease-III-like ResIII PF04851.10 EMR71609.1 - 1.2e-13 51.3 0.1 3e-13 50.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EMR71609.1 - 1.8e-12 47.0 0.0 3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EMR71609.1 - 8.8e-05 21.4 0.1 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Peptidase_S8 PF00082.17 EMR71610.1 - 2e-49 168.2 4.9 2.9e-49 167.7 3.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMR71610.1 - 1.1e-12 48.3 0.0 1.9e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 TAP42 PF04177.7 EMR71612.1 - 6.7e-105 350.7 0.2 7.6e-105 350.6 0.1 1.0 1 0 0 1 1 1 1 TAP42-like family DUF1399 PF07173.7 EMR71612.1 - 0.05 13.8 0.1 3.7 7.8 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1399) PhoD PF09423.5 EMR71613.1 - 2.1e-143 478.2 2.8 2.4e-143 478.0 1.9 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EMR71613.1 - 0.091 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain 2-Hacid_dh_C PF02826.14 EMR71614.1 - 2.5e-53 179.8 0.0 3.4e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EMR71614.1 - 1.7e-18 66.3 0.0 5.7e-18 64.6 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EMR71614.1 - 2e-07 30.9 0.1 3.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EMR71614.1 - 0.0032 17.8 0.1 0.0059 17.0 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EMR71614.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain adh_short PF00106.20 EMR71614.1 - 0.011 15.6 3.6 0.023 14.6 2.5 1.5 1 0 0 1 1 1 0 short chain dehydrogenase XdhC_C PF13478.1 EMR71614.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Epimerase PF01370.16 EMR71615.1 - 1.2e-18 67.4 0.0 1.5e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMR71615.1 - 1.3e-08 34.9 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EMR71615.1 - 1.9e-08 33.3 0.0 2.4e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EMR71615.1 - 1.4e-06 27.4 0.0 2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EMR71615.1 - 2.6e-05 23.2 0.0 0.0011 17.9 0.0 2.2 1 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EMR71615.1 - 0.00034 20.6 0.0 0.00049 20.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMR71615.1 - 0.0039 16.8 0.0 0.0087 15.7 0.0 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EMR71615.1 - 0.15 10.9 0.0 1.2 7.9 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 EMR71615.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF2457 PF10446.4 EMR71616.1 - 0.21 10.2 5.5 0.27 9.9 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC73 PF05179.9 EMR71618.1 - 2.7e-46 158.1 0.0 5.8e-46 157.0 0.0 1.6 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family NmrA PF05368.8 EMR71619.1 - 0.017 14.4 0.1 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Cellulase PF00150.13 EMR71620.1 - 1e-17 64.2 4.1 1.4e-17 63.8 2.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Antig_Caf1 PF09255.5 EMR71620.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Caf1 Capsule antigen SGL PF08450.7 EMR71621.1 - 1.2e-16 60.8 1.5 3.7e-16 59.2 0.8 1.9 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Ferritin PF00210.19 EMR71623.1 - 0.057 13.1 0.1 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Ferritin-like domain EHN PF06441.7 EMR71626.1 - 1.5e-31 108.5 1.1 1.8e-31 108.3 0.0 1.7 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EMR71626.1 - 7.1e-13 48.9 0.0 1.3e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR71626.1 - 9.5e-12 44.9 0.2 2.1e-10 40.5 0.0 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Glutaredoxin PF00462.19 EMR71627.1 - 1.5e-17 63.3 0.0 1e-16 60.6 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EMR71627.1 - 5e-13 48.6 0.0 1.4e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 EMR71627.1 - 0.057 13.5 0.0 3.5 7.7 0.0 2.5 1 1 1 2 2 2 0 Thioredoxin-like Glyco_hydro_9 PF00759.14 EMR71627.1 - 0.064 12.1 0.7 0.12 11.2 0.5 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Ribosomal_60s PF00428.14 EMR71627.1 - 0.68 10.3 8.3 1.6 9.2 5.8 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein CoatB PF10389.4 EMR71628.1 - 0.48 10.3 3.8 0.21 11.4 0.7 1.8 2 0 0 2 2 2 0 Bacteriophage coat protein B LSM PF01423.17 EMR71629.1 - 6.7e-16 57.6 0.2 8.7e-16 57.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain IU_nuc_hydro PF01156.14 EMR71630.1 - 2.5e-53 181.3 0.0 4.2e-52 177.3 0.0 2.1 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Cactin_mid PF10312.4 EMR71631.1 - 1.1e-60 204.1 4.5 1.6e-60 203.6 3.1 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EMR71631.1 - 7.5e-50 167.7 1.9 1.3e-49 166.9 1.3 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.8 EMR71631.1 - 0.026 14.4 4.8 0.044 13.7 0.2 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF3632 PF12311.3 EMR71632.1 - 4e-31 108.2 0.6 5.6e-31 107.7 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Slx4 PF09494.5 EMR71633.1 - 1.7e-21 75.6 0.0 4.2e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 Slx4 endonuclease IL1_propep PF02394.11 EMR71633.1 - 0.021 15.1 0.5 0.15 12.4 0.1 2.4 2 0 0 2 2 2 0 Interleukin-1 propeptide FAD_binding_7 PF03441.9 EMR71634.1 - 3.3e-101 338.1 0.2 5.6e-101 337.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EMR71634.1 - 1.4e-35 122.4 0.0 2.4e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 EMR71634.1 - 0.0046 17.1 0.2 0.013 15.6 0.2 1.8 1 0 0 1 1 1 1 Universal stress protein family adh_short PF00106.20 EMR71635.1 - 4.8e-14 52.6 0.1 8.5e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR71635.1 - 2.9e-05 23.8 0.4 5.3e-05 22.9 0.3 1.3 1 0 0 1 1 1 1 KR domain PEP_mutase PF13714.1 EMR71636.1 - 7.4e-42 143.2 0.2 4.8e-31 107.8 0.0 2.1 1 1 1 2 2 2 2 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EMR71636.1 - 7.2e-11 40.9 0.3 1.1e-10 40.4 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 EMR71636.1 - 0.0001 21.5 0.1 0.012 14.7 0.1 2.2 1 1 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Sua5_yciO_yrdC PF01300.13 EMR71636.1 - 0.079 12.2 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Telomere recombination DAHP_synth_1 PF00793.15 EMR71636.1 - 0.12 11.0 0.1 0.59 8.7 0.0 2.1 1 1 2 3 3 3 0 DAHP synthetase I family Ribosomal_S21e PF01249.13 EMR71637.1 - 3.2e-40 135.9 0.1 3.5e-40 135.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e MFS_1 PF07690.11 EMR71638.1 - 6.5e-25 87.5 48.4 6.5e-25 87.5 33.5 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EMR71639.1 - 2.9e-19 69.0 18.7 7.2e-19 67.7 12.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily FtsJ PF01728.14 EMR71640.1 - 1.6e-53 181.3 0.0 2.5e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EMR71640.1 - 2.4e-44 150.6 7.4 3.9e-44 149.9 5.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) DUF4519 PF15012.1 EMR71640.1 - 0.0081 16.0 0.7 0.016 15.1 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) SnoaL PF07366.7 EMR71641.1 - 2e-23 82.3 0.0 6.7e-14 51.5 0.0 2.1 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EMR71641.1 - 7.8e-13 48.7 0.1 1.4e-06 28.6 0.1 2.2 2 0 0 2 2 2 2 SnoaL-like domain His_Phos_2 PF00328.17 EMR71642.1 - 4.4e-16 59.1 0.0 3.5e-12 46.3 0.0 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) SUN PF03856.8 EMR71643.1 - 2.3e-33 115.5 1.0 2.8e-33 115.2 0.7 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Sugar_tr PF00083.19 EMR71644.1 - 5.1e-116 387.9 29.9 5.9e-116 387.7 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR71644.1 - 1.2e-17 63.6 41.5 2.7e-17 62.5 22.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 EMR71644.1 - 0.00061 18.6 5.7 0.0013 17.5 4.0 1.5 1 0 0 1 1 1 1 PUCC protein TRI12 PF06609.8 EMR71644.1 - 0.021 13.0 6.7 0.013 13.7 1.7 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.4 EMR71644.1 - 0.59 10.1 6.4 0.21 11.5 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Cupin_1 PF00190.17 EMR71645.1 - 9.2e-13 47.8 0.3 1.7e-12 47.0 0.2 1.4 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EMR71645.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Herpes_BLLF1 PF05109.8 EMR71648.1 - 2.2 6.1 4.5 2.3 6.0 3.1 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) NACHT PF05729.7 EMR71649.1 - 2e-08 34.0 0.4 1.1e-07 31.6 0.0 2.3 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EMR71649.1 - 1.6e-05 24.9 0.6 0.0015 18.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EMR71649.1 - 0.00019 20.9 0.1 0.013 14.9 0.0 2.5 2 1 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EMR71649.1 - 0.00072 19.6 0.2 0.011 15.8 0.0 2.5 2 2 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EMR71649.1 - 0.0021 16.9 0.0 0.0061 15.4 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 EMR71649.1 - 0.0034 17.5 0.6 0.036 14.2 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EMR71649.1 - 0.0042 16.5 0.1 0.11 11.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 EMR71649.1 - 0.0058 16.3 0.0 0.019 14.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EMR71649.1 - 0.032 14.1 0.0 0.25 11.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EMR71649.1 - 0.038 13.3 0.5 0.2 11.0 0.1 2.3 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EMR71649.1 - 0.04 13.5 0.1 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF2075 PF09848.4 EMR71649.1 - 0.063 12.2 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_13 PF13166.1 EMR71649.1 - 0.11 10.9 0.2 0.2 10.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMR71649.1 - 0.15 12.2 0.0 0.55 10.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ABC2_membrane PF01061.19 EMR71650.1 - 5.4e-27 94.3 25.9 7.2e-27 93.9 18.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EMR71650.1 - 1.4e-23 83.7 0.0 2.8e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMR71650.1 - 4.2e-06 26.9 0.0 0.036 14.0 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EMR71650.1 - 1.3e-05 25.2 0.1 2.3e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EMR71650.1 - 3.7e-05 23.2 0.0 0.00052 19.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EMR71650.1 - 9.9e-05 21.5 0.0 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMR71650.1 - 0.00016 21.8 0.0 0.00053 20.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain PDR_CDR PF06422.7 EMR71650.1 - 0.0014 18.2 0.0 0.005 16.4 0.0 2.0 1 0 0 1 1 1 1 CDR ABC transporter cobW PF02492.14 EMR71650.1 - 0.0051 16.2 0.4 0.017 14.5 0.1 1.9 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EMR71650.1 - 0.0056 17.5 0.0 0.013 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EMR71650.1 - 0.0069 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMR71650.1 - 0.0073 16.5 0.0 0.053 13.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EMR71650.1 - 0.0093 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase PduV-EutP PF10662.4 EMR71650.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.14 EMR71650.1 - 0.019 14.2 0.0 0.081 12.1 0.0 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EMR71650.1 - 0.023 15.0 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EMR71650.1 - 0.023 13.4 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EMR71650.1 - 0.027 14.2 0.1 0.064 13.0 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EMR71650.1 - 0.034 13.8 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EMR71650.1 - 0.042 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EMR71650.1 - 0.045 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 EMR71650.1 - 0.051 13.5 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EMR71650.1 - 0.078 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EMR71650.1 - 0.1 12.5 0.0 0.1 12.5 0.0 2.2 2 1 0 2 2 1 0 50S ribosome-binding GTPase SSP160 PF06933.6 EMR71650.1 - 0.21 9.5 7.8 0.3 9.0 5.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AAA_15 PF13175.1 EMR71650.1 - 0.32 9.9 0.0 6.8 5.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF3439 PF11921.3 EMR71650.1 - 4.6 7.0 12.5 13 5.5 8.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sugar_tr PF00083.19 EMR71651.1 - 2.5e-79 266.9 26.9 3.1e-79 266.6 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR71651.1 - 1.4e-30 106.2 57.3 6.2e-25 87.6 20.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EMR71651.1 - 1.3e-05 23.4 3.1 0.0014 16.7 0.9 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.13 EMR71652.1 - 3.3e-08 33.3 9.3 6.5e-08 32.3 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EMR71652.1 - 2.6e-06 26.2 0.9 7.6e-06 24.7 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Amidase PF01425.16 EMR71653.1 - 1.6e-97 327.1 0.0 2e-97 326.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Zn_clus PF00172.13 EMR71654.1 - 1e-09 38.1 7.3 1.9e-09 37.2 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMR71654.1 - 5.4e-05 22.1 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAN_4 PF14295.1 EMR71655.1 - 0.0082 15.8 0.5 0.017 14.7 0.3 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EMR71655.1 - 0.04 13.6 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 PAN domain bZIP_C PF12498.3 EMR71655.1 - 2.3 9.4 7.1 0.4 11.9 0.5 2.3 2 1 0 2 2 2 0 Basic leucine-zipper C terminal MFS_1 PF07690.11 EMR71656.1 - 1.8e-34 118.9 19.5 1.8e-34 118.9 13.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ADH_zinc_N_2 PF13602.1 EMR71657.1 - 3.7e-24 86.0 0.3 7e-24 85.1 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EMR71657.1 - 2.4e-17 62.6 0.2 6.1e-17 61.3 0.1 1.6 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR71657.1 - 7e-05 22.5 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EMR71657.1 - 0.0061 16.5 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 EMR71657.1 - 0.31 10.5 1.6 0.45 10.0 0.3 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MmgE_PrpD PF03972.9 EMR71658.1 - 9.7e-73 244.8 1.6 1.2e-72 244.5 1.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family NicO PF03824.11 EMR71659.1 - 5.2e-55 186.7 5.6 4e-53 180.5 3.9 2.2 1 1 0 1 1 1 1 High-affinity nickel-transport protein HAMP PF00672.20 EMR71659.1 - 0.45 10.7 0.1 0.45 10.7 0.0 3.7 4 0 0 4 4 4 0 HAMP domain Kelch_1 PF01344.20 EMR71660.1 - 9.4e-44 146.7 11.9 1.1e-09 37.6 0.0 7.9 7 1 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 EMR71660.1 - 2.1e-40 135.2 12.2 3.2e-09 36.5 0.0 7.0 5 3 2 7 7 7 6 Kelch motif Kelch_3 PF13415.1 EMR71660.1 - 9.8e-27 92.4 16.6 1.4e-06 28.3 0.0 6.5 6 1 1 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.10 EMR71660.1 - 1.5e-26 91.1 2.0 1e-05 25.0 0.0 7.0 6 2 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 EMR71660.1 - 1.6e-24 85.3 13.9 2.1e-05 24.2 0.0 6.5 6 2 1 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EMR71660.1 - 8.5e-18 63.9 9.3 0.0021 17.9 0.0 5.8 6 0 0 6 6 6 5 Kelch motif Head_binding PF09008.5 EMR71660.1 - 0.087 12.8 0.1 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Head binding DnaG_DnaB_bind PF08278.6 EMR71661.1 - 0.14 12.4 0.2 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding PLAC8 PF04749.12 EMR71662.1 - 6.3e-19 68.4 4.5 8.2e-19 68.1 3.1 1.1 1 0 0 1 1 1 1 PLAC8 family DUF2742 PF10888.3 EMR71663.1 - 0.021 14.7 0.2 0.034 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) Harakiri PF15196.1 EMR71666.1 - 0.55 10.5 11.8 2.3 8.5 1.3 2.4 2 1 0 2 2 2 0 Activator of apoptosis harakiri FRG2 PF15315.1 EMR71666.1 - 4.6 7.1 25.8 1.7 8.5 8.5 2.4 1 1 2 3 3 3 0 Facioscapulohumeral muscular dystrophy candidate 2 p450 PF00067.17 EMR71667.1 - 5.3e-45 153.7 0.0 5.1e-44 150.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Tim54 PF11711.3 EMR71668.1 - 0.075 11.6 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FCD PF07729.7 EMR71668.1 - 0.1 12.9 1.4 3.2 8.0 0.3 3.0 3 1 0 3 3 3 0 FCD domain Sigma70_ner PF04546.8 EMR71668.1 - 0.95 9.0 7.9 0.4 10.2 2.6 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region UQ_con PF00179.21 EMR71669.1 - 2.1e-07 30.4 0.0 3.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box-like PF12937.2 EMR71669.1 - 0.0017 18.0 0.1 0.004 16.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like RWD PF05773.17 EMR71669.1 - 0.0044 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 RWD domain An_peroxidase PF03098.10 EMR71669.1 - 0.032 12.6 0.1 0.047 12.0 0.0 1.2 1 0 0 1 1 1 0 Animal haem peroxidase Glyco_hydro_10 PF00331.15 EMR71670.1 - 6.8e-59 199.4 1.7 8.2e-59 199.2 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4339 PF14237.1 EMR71670.1 - 0.0036 16.8 0.2 0.011 15.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) Cellulase-like PF12876.2 EMR71670.1 - 0.091 13.2 0.0 0.38 11.2 0.0 2.0 2 0 0 2 2 2 0 Sugar-binding cellulase-like AAA PF00004.24 EMR71671.1 - 8.5e-16 58.3 0.0 2.1e-15 57.0 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR71671.1 - 0.02 15.0 0.3 0.12 12.5 0.0 2.3 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 EMR71671.1 - 0.05 14.4 1.0 0.4 11.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EMR71671.1 - 0.13 11.3 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Sel1 PF08238.7 EMR71673.1 - 8.8e-36 121.5 44.8 4.3e-05 24.0 0.1 13.2 14 1 0 14 14 14 9 Sel1 repeat GRP PF07172.6 EMR71673.1 - 0.0012 19.2 3.1 0.0036 17.7 2.2 1.9 1 0 0 1 1 1 1 Glycine rich protein family OPA3 PF07047.7 EMR71673.1 - 0.11 12.3 1.0 0.19 11.4 0.7 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) TMEM51 PF15345.1 EMR71673.1 - 0.47 10.1 1.9 0.78 9.3 1.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 FHIPEP PF00771.15 EMR71673.1 - 0.63 8.2 0.6 0.97 7.6 0.4 1.2 1 0 0 1 1 1 0 FHIPEP family TPR_6 PF13174.1 EMR71673.1 - 7 7.3 19.0 6 7.5 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat 2OG-FeII_Oxy PF03171.15 EMR71674.1 - 0.0016 18.7 0.0 0.0076 16.5 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily XPG_N PF00752.12 EMR71675.1 - 0.11 12.8 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 XPG N-terminal domain WD40 PF00400.27 EMR71676.1 - 5.9e-06 25.9 0.7 0.19 11.6 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat FRG1 PF06229.7 EMR71677.1 - 4.4e-51 173.0 0.1 6.8e-51 172.4 0.1 1.3 1 0 0 1 1 1 1 FRG1-like family Pkinase PF00069.20 EMR71678.1 - 7.6e-71 238.2 0.0 1.7e-70 237.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR71678.1 - 8.7e-38 129.8 0.0 2e-37 128.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR71678.1 - 2.5e-05 23.3 0.0 5e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EMR71678.1 - 0.018 14.1 0.1 0.038 13.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EMR71678.1 - 0.056 13.1 2.4 0.16 11.6 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family PAP2 PF01569.16 EMR71681.1 - 5e-15 55.3 1.8 5e-15 55.3 1.2 1.7 2 0 0 2 2 2 1 PAP2 superfamily DUF716 PF04819.7 EMR71681.1 - 0.0093 15.4 4.5 0.041 13.3 0.9 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF716) DUF212 PF02681.9 EMR71681.1 - 0.015 14.9 0.0 0.098 12.3 0.0 2.0 2 0 0 2 2 2 0 Divergent PAP2 family DUF2374 PF09574.5 EMR71681.1 - 0.18 11.4 2.5 0.68 9.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) PrgI PF12666.2 EMR71681.1 - 5.8 7.1 6.0 0.54 10.4 0.2 2.2 3 1 0 3 3 3 0 PrgI family protein DUF3328 PF11807.3 EMR71682.1 - 7e-38 130.4 0.1 8.3e-38 130.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2331 PF10093.4 EMR71682.1 - 0.083 11.6 0.1 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2331) Abhydrolase_4 PF08386.5 EMR71683.1 - 1.2e-17 63.6 0.0 2.7e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EMR71683.1 - 2.9e-10 40.4 0.0 2.5e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR71683.1 - 3.1e-10 40.0 1.9 4.3e-08 32.9 0.3 2.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR71683.1 - 0.0004 20.1 0.0 0.19 11.4 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Pyr_redox_2 PF07992.9 EMR71684.1 - 4.6e-12 46.2 0.1 7.5e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR71684.1 - 6.9e-12 45.5 0.8 3.4e-08 33.7 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR71684.1 - 1.4e-07 31.7 2.0 0.0056 16.7 0.1 3.2 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR71684.1 - 7.6e-06 25.7 0.5 0.097 12.4 0.0 3.8 3 1 1 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMR71684.1 - 0.00062 18.7 0.1 0.049 12.5 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EMR71684.1 - 0.00087 18.2 5.9 0.71 8.7 0.0 3.8 3 1 0 4 4 4 2 FAD dependent oxidoreductase TrkA_N PF02254.13 EMR71684.1 - 0.0021 18.0 0.0 0.76 9.7 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain Saccharop_dh PF03435.13 EMR71684.1 - 0.0046 15.9 0.0 0.055 12.4 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase DUF1194 PF06707.6 EMR71684.1 - 0.038 12.9 0.4 0.058 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Lycopene_cycl PF05834.7 EMR71684.1 - 0.061 12.2 0.3 0.94 8.3 0.0 2.7 3 1 1 4 4 4 0 Lycopene cyclase protein AAA_26 PF13500.1 EMR71684.1 - 0.09 12.3 0.1 6.2 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain IBR PF01485.16 EMR71685.1 - 6.6e-07 29.1 14.1 2.9e-06 27.0 0.1 3.1 2 1 1 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EMR71685.1 - 1.6e-05 24.6 7.7 1.6e-05 24.6 5.3 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMR71685.1 - 0.00021 21.2 8.1 0.00045 20.1 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EMR71685.1 - 0.00028 20.4 7.9 0.0008 19.0 5.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMR71685.1 - 0.0032 17.1 4.9 0.01 15.5 3.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EMR71685.1 - 0.0036 16.9 8.8 0.008 15.8 6.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMR71685.1 - 0.026 14.3 7.0 0.11 12.3 4.9 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_RING PF05883.6 EMR71685.1 - 0.15 11.8 1.7 0.34 10.7 1.2 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Sterol_MT_C PF08498.5 EMR71686.1 - 2.2e-27 94.7 0.2 3.6e-27 94.0 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EMR71686.1 - 1e-21 77.2 0.0 1.9e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR71686.1 - 4.4e-18 65.3 0.0 6.8e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR71686.1 - 5e-14 52.3 0.1 8.9e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR71686.1 - 8.1e-14 51.8 0.1 2.4e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EMR71686.1 - 2.6e-12 46.3 0.1 3.6e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EMR71686.1 - 1.5e-11 44.8 0.0 4.3e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR71686.1 - 3e-11 42.8 0.0 5.1e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMR71686.1 - 3.1e-11 43.5 0.0 1.1e-10 41.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR71686.1 - 1.7e-09 37.7 0.0 5.2e-09 36.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EMR71686.1 - 6e-05 22.6 0.0 9.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EMR71686.1 - 9e-05 21.9 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EMR71686.1 - 0.00022 20.4 0.1 0.00089 18.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EMR71686.1 - 0.00027 20.5 0.1 0.00043 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EMR71686.1 - 0.001 18.1 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.7 EMR71686.1 - 0.0016 17.8 0.0 0.0037 16.6 0.0 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.11 EMR71686.1 - 0.0086 14.4 0.0 0.013 13.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TehB PF03848.9 EMR71686.1 - 0.028 13.5 0.3 0.062 12.4 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_2 PF00891.13 EMR71686.1 - 0.043 12.9 0.5 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_32 PF13679.1 EMR71686.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 EMR71686.1 - 0.048 14.5 0.3 0.19 12.6 0.0 2.2 3 0 0 3 3 1 0 Methyltransferase domain PA PF02225.17 EMR71687.1 - 3.1e-13 49.2 0.0 8.7e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 PA domain CoA_transf_3 PF02515.12 EMR71688.1 - 1.4e-18 66.8 0.0 3e-17 62.4 0.0 2.3 2 0 0 2 2 2 2 CoA-transferase family III ADH_zinc_N PF00107.21 EMR71689.1 - 2.7e-06 26.9 0.1 5.3e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR71689.1 - 2.9e-05 23.7 0.0 0.00017 21.2 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 EMR71689.1 - 0.036 14.3 0.0 0.072 13.3 0.0 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Vezatin PF12632.2 EMR71690.1 - 6.1e-26 91.0 0.1 1.2e-25 90.0 0.0 1.6 1 1 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF3678 PF12435.3 EMR71690.1 - 1.6 8.3 4.4 12 5.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) KH_1 PF00013.24 EMR71691.1 - 2.5e-37 126.3 8.3 4.5e-16 58.2 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EMR71691.1 - 3.4e-30 103.1 13.4 2.5e-11 42.9 2.8 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EMR71691.1 - 5.4e-11 41.8 7.9 0.0068 15.9 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EMR71691.1 - 0.00035 20.1 1.6 1.2 8.8 0.1 3.2 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EMR71691.1 - 0.0038 16.9 7.7 0.81 9.5 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain GPI-anchored PF10342.4 EMR71692.1 - 2.2e-18 66.5 0.1 4.7e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1517 PF07466.6 EMR71692.1 - 8.6 5.2 8.4 0.73 8.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) OB_NTP_bind PF07717.11 EMR71693.1 - 2.2e-16 59.6 0.0 7.8e-16 57.9 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMR71693.1 - 2.8e-16 59.4 0.0 7.5e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMR71693.1 - 1.8e-11 43.7 0.0 5.9e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMR71693.1 - 3.2e-07 30.0 0.0 8.7e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMR71693.1 - 0.0012 18.9 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EMR71693.1 - 0.019 14.5 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EMR71693.1 - 0.045 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EMR71693.1 - 0.05 13.5 3.3 0.095 12.6 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain Kinesin PF00225.18 EMR71693.1 - 0.16 10.6 0.0 0.26 9.9 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain Peptidase_M1 PF01433.15 EMR71694.1 - 7e-140 466.5 0.1 9.4e-140 466.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EMR71694.1 - 9.4e-91 304.4 0.0 1.7e-90 303.5 0.0 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EMR71694.1 - 2.5e-19 69.5 0.3 5.4e-19 68.4 0.2 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily DUF1360 PF07098.6 EMR71694.1 - 0.16 11.6 0.2 0.38 10.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) PCNA_C PF02747.10 EMR71695.1 - 2.6e-50 169.6 0.0 4.7e-50 168.7 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 EMR71695.1 - 4.3e-50 168.4 9.1 2.3e-48 162.9 1.8 2.6 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 EMR71695.1 - 1.2e-11 44.2 0.1 1.6e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EMR71695.1 - 0.0044 15.9 0.3 0.048 12.5 0.0 2.2 1 1 1 2 2 2 1 Hus1-like protein PSD1 PF07587.6 EMR71695.1 - 0.056 12.8 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) dUTPase PF00692.14 EMR71696.1 - 7.6e-42 141.8 0.0 1e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 dUTPase Pex14_N PF04695.8 EMR71696.1 - 0.065 13.2 4.5 0.1 12.6 3.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAP1 PF08601.5 EMR71696.1 - 0.47 10.0 5.1 0.55 9.8 3.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Methyltransf_16 PF10294.4 EMR71698.1 - 0.0041 16.5 0.0 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase DUF2298 PF10060.4 EMR71698.1 - 0.053 12.3 0.1 0.082 11.7 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) Nsp1_C PF05064.8 EMR71699.1 - 1.4e-34 118.2 7.7 1.5e-34 118.1 4.4 1.7 1 1 0 1 1 1 1 Nsp1-like C-terminal region Myosin_tail_1 PF01576.14 EMR71699.1 - 0.001 16.9 5.8 0.0019 16.0 4.0 1.4 1 1 0 1 1 1 1 Myosin tail SGT1 PF07093.6 EMR71699.1 - 0.0063 14.9 3.1 0.0063 14.9 2.1 1.1 1 0 0 1 1 1 1 SGT1 protein WXG100 PF06013.7 EMR71699.1 - 0.0085 16.0 3.9 0.58 10.2 0.1 3.3 3 1 0 3 3 3 1 Proteins of 100 residues with WXG APG6 PF04111.7 EMR71699.1 - 0.012 14.7 2.8 0.02 13.9 1.8 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 EMR71699.1 - 0.051 13.4 5.2 0.083 12.7 3.2 1.7 1 1 0 1 1 1 0 Tropomyosin like AAA_13 PF13166.1 EMR71699.1 - 0.061 11.7 2.7 0.1 11.0 0.4 1.7 1 1 1 2 2 2 0 AAA domain MtrG PF04210.8 EMR71699.1 - 0.07 12.8 0.5 5.6 6.7 0.1 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G TMCO5 PF14992.1 EMR71699.1 - 0.085 11.9 3.7 0.11 11.6 2.6 1.2 1 0 0 1 1 1 0 TMCO5 family RmuC PF02646.11 EMR71699.1 - 0.086 11.6 1.5 0.27 10.0 0.1 2.3 1 1 1 2 2 2 0 RmuC family Baculo_PEP_C PF04513.7 EMR71699.1 - 0.097 12.4 0.2 0.7 9.7 0.0 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-SNARE PF05008.10 EMR71699.1 - 0.11 12.7 7.8 2.4 8.3 0.1 3.4 3 1 0 4 4 3 0 Vesicle transport v-SNARE protein N-terminus MCPsignal PF00015.16 EMR71699.1 - 0.11 12.0 0.9 0.71 9.3 0.1 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Reo_sigmaC PF04582.7 EMR71699.1 - 0.11 11.6 0.3 0.29 10.2 0.1 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4559 PF15112.1 EMR71699.1 - 0.13 11.4 1.9 0.26 10.3 0.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) DUF4200 PF13863.1 EMR71699.1 - 0.18 11.7 4.9 1 9.3 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.7 EMR71699.1 - 0.31 11.3 4.1 1.3 9.3 0.0 3.0 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein Phasin PF05597.6 EMR71699.1 - 0.32 10.7 4.5 0.5 10.1 0.8 2.4 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Laminin_II PF06009.7 EMR71699.1 - 0.33 10.7 4.9 0.54 10.0 0.3 2.5 2 2 0 2 2 2 0 Laminin Domain II Fib_alpha PF08702.5 EMR71699.1 - 0.36 10.9 2.3 2.2 8.3 0.1 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family COG2 PF06148.6 EMR71699.1 - 0.43 10.4 2.8 2 8.3 0.6 2.6 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ApoLp-III PF07464.6 EMR71699.1 - 0.56 10.2 5.8 23 4.9 1.7 3.1 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) IncA PF04156.9 EMR71699.1 - 0.69 9.4 6.9 4 7.0 4.8 2.1 1 1 0 1 1 1 0 IncA protein DUF16 PF01519.11 EMR71699.1 - 0.73 10.0 5.6 31 4.8 3.9 2.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 CENP-Q PF13094.1 EMR71699.1 - 0.88 9.5 6.1 5.6 6.9 4.1 2.2 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit MscS_porin PF12795.2 EMR71699.1 - 1.1 8.5 6.8 2.9 7.1 0.4 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Spc24 PF08286.6 EMR71699.1 - 2.5 7.7 6.5 26 4.5 0.9 3.2 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 zf-CSL PF05207.8 EMR71700.1 - 7e-16 57.4 1.4 1.3e-15 56.6 1.0 1.5 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EMR71700.1 - 1.4e-13 50.3 5.4 7.9e-13 47.9 2.2 2.6 2 1 0 2 2 2 1 DnaJ domain Phos_pyr_kin PF08543.7 EMR71701.1 - 1.3e-10 40.8 0.0 2.5e-10 39.9 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EMR71701.1 - 6.9e-10 38.5 1.9 5.6e-08 32.2 0.1 2.5 2 1 0 2 2 2 1 pfkB family carbohydrate kinase 14-3-3 PF00244.15 EMR71702.1 - 1.4e-116 387.5 3.2 1.7e-116 387.3 2.2 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_M17_N PF02789.12 EMR71702.1 - 0.043 13.5 0.2 0.28 10.9 0.0 2.3 2 1 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Rab5ip PF07019.7 EMR71703.1 - 4.4e-21 74.8 7.2 5.7e-21 74.4 5.0 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) IATP PF04568.7 EMR71704.1 - 4.7e-21 74.6 0.6 5.4e-21 74.5 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Complex1_LYR PF05347.10 EMR71705.1 - 3.9e-06 26.5 0.0 1.1e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EMR71705.1 - 0.00013 22.1 0.2 0.00069 19.7 0.0 2.3 2 0 0 2 2 2 1 Complex1_LYR-like SNARE PF05739.14 EMR71705.1 - 0.0019 17.8 0.5 0.096 12.3 0.0 2.7 2 0 0 2 2 2 1 SNARE domain Complex1_LYR_2 PF13233.1 EMR71705.1 - 0.0045 17.4 0.0 0.0045 17.4 0.0 2.8 2 1 0 2 2 2 1 Complex1_LYR-like V-SNARE_C PF12352.3 EMR71705.1 - 0.0049 16.8 1.7 0.086 12.9 0.2 2.6 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus N6_Mtase PF02384.11 EMR71705.1 - 0.0061 15.6 1.1 0.0087 15.1 0.3 1.5 2 0 0 2 2 2 1 N-6 DNA Methylase DUF948 PF06103.6 EMR71705.1 - 0.15 11.9 0.9 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pyr_redox_3 PF13738.1 EMR71707.1 - 6e-18 65.6 0.0 2.2e-17 63.8 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR71707.1 - 5.3e-09 34.8 0.0 1.3e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMR71707.1 - 3.4e-08 33.3 0.0 8.3e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EMR71707.1 - 2.9e-05 23.1 0.0 0.024 13.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMR71707.1 - 0.0016 18.3 0.0 0.062 13.1 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR71707.1 - 0.056 13.2 0.5 1.2 8.9 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding MFS_1 PF07690.11 EMR71708.1 - 1.4e-26 93.0 40.2 2.8e-20 72.3 15.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 EMR71708.1 - 1.8 9.0 3.9 2 8.8 0.0 2.5 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CENP-K PF11802.3 EMR71709.1 - 5.4e-12 45.5 0.6 1.9e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Centromere-associated protein K ImcF-related_N PF14331.1 EMR71709.1 - 0.1 11.4 8.0 1 8.1 0.4 2.2 2 0 0 2 2 2 0 ImcF-related N-terminal domain Filament PF00038.16 EMR71709.1 - 0.47 9.8 16.4 0.038 13.4 5.6 2.1 2 0 0 2 2 2 0 Intermediate filament protein PSII_Pbs27 PF13326.1 EMR71709.1 - 0.54 10.2 4.4 1.6 8.7 0.8 2.8 2 1 0 2 2 2 0 Photosystem II Pbs27 FUSC PF04632.7 EMR71709.1 - 1.4 7.2 7.3 1.9 6.8 5.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DinB_2 PF12867.2 EMR71709.1 - 1.6 9.0 4.6 16 5.8 0.2 2.7 2 1 1 3 3 3 0 DinB superfamily MAT1 PF06391.8 EMR71709.1 - 1.9 8.0 11.0 0.24 10.9 2.5 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 BTV_NS2 PF04514.7 EMR71709.1 - 4.3 6.1 11.7 1.5 7.6 1.8 2.0 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Mnd1 PF03962.10 EMR71709.1 - 7.3 6.2 14.0 0.83 9.2 2.9 2.3 2 0 0 2 2 2 0 Mnd1 family DEAD PF00270.24 EMR71710.1 - 4e-43 146.8 0.0 4.5e-42 143.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR71710.1 - 3.2e-25 87.7 0.1 6.7e-25 86.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR71710.1 - 0.00093 19.0 0.1 0.01 15.6 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2986 PF11661.3 EMR71710.1 - 0.0011 19.1 5.6 0.0011 19.1 3.9 2.8 4 0 0 4 4 4 1 Protein of unknown function (DUF2986) PRAI PF00697.17 EMR71710.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase SpoU_methylase PF00588.14 EMR71710.1 - 0.15 11.9 0.1 0.67 9.8 0.0 2.1 1 1 1 2 2 2 0 SpoU rRNA Methylase family CMS1 PF14617.1 EMR71710.1 - 0.15 11.1 0.0 0.15 11.1 0.0 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Aldose_epim PF01263.15 EMR71711.1 - 3.3e-48 164.3 0.4 4.4e-48 163.9 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF1115 PF06544.7 EMR71712.1 - 1.3e-18 66.9 0.0 3.2e-18 65.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Lactamase_B PF00753.22 EMR71714.1 - 9.4e-06 25.3 5.0 0.00014 21.5 3.5 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EMR71714.1 - 0.00015 21.3 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pectate_lyase PF03211.8 EMR71715.1 - 1.6e-61 207.4 1.9 2.1e-61 207.0 1.3 1.1 1 0 0 1 1 1 1 Pectate lyase P21-Arc PF04062.9 EMR71716.1 - 1.6e-79 265.7 0.0 1.8e-79 265.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.13 EMR71716.1 - 0.0067 16.4 1.5 0.018 15.0 1.0 1.6 1 0 0 1 1 1 1 Pancreatic hormone peptide ATP-synt_ab PF00006.20 EMR71717.1 - 2.9e-60 203.4 0.0 4e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EMR71717.1 - 3.9e-16 59.5 0.1 7.4e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EMR71717.1 - 2.9e-12 46.6 0.6 5.1e-12 45.8 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EMR71717.1 - 0.0021 17.9 0.3 0.0043 16.9 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain Gcd10p PF04189.8 EMR71718.1 - 3e-60 203.8 0.0 1.4e-59 201.7 0.0 2.0 1 1 0 1 1 1 1 Gcd10p family Zip PF02535.17 EMR71718.1 - 0.056 12.4 6.3 0.089 11.7 4.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EMR71718.1 - 2.8 7.2 12.8 4.7 6.5 8.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.4 EMR71718.1 - 5.5 5.1 8.4 8.2 4.5 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein ADH_zinc_N PF00107.21 EMR71719.1 - 2.8e-20 72.1 0.0 4.7e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR71719.1 - 1.3e-16 60.2 0.5 2.7e-15 56.0 0.2 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EMR71719.1 - 0.13 11.8 1.3 0.27 10.9 0.9 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated tRNA-synt_1g PF09334.6 EMR71720.1 - 2e-134 448.1 0.1 1.1e-132 442.4 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EMR71720.1 - 3.8e-09 35.1 0.1 0.0015 16.6 0.0 4.2 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMR71720.1 - 0.0012 18.5 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Laminin_EGF PF00053.19 EMR71720.1 - 0.092 12.6 1.8 0.19 11.7 1.3 1.4 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) Sugar_tr PF00083.19 EMR71721.1 - 4.7e-90 302.3 21.2 5.8e-90 302.0 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR71721.1 - 3.9e-30 104.7 31.8 3.7e-20 71.9 5.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR71721.1 - 0.0015 16.7 1.7 0.0015 16.7 1.2 2.3 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EMR71721.1 - 0.23 9.4 18.0 0.069 11.1 1.7 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TraF PF13728.1 EMR71722.1 - 0.014 14.8 0.2 0.024 14.1 0.1 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein IncA PF04156.9 EMR71722.1 - 0.015 14.9 1.2 0.015 14.9 0.8 1.9 2 0 0 2 2 2 0 IncA protein DUF745 PF05335.8 EMR71722.1 - 0.046 13.2 1.5 0.087 12.3 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Prefoldin_2 PF01920.15 EMR71722.1 - 0.074 12.8 7.6 0.16 11.7 2.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit Rab5-bind PF09311.6 EMR71722.1 - 0.19 11.5 6.3 0.037 13.9 1.7 1.7 2 0 0 2 2 2 0 Rabaptin-like protein Spc24 PF08286.6 EMR71722.1 - 0.24 11.1 3.2 0.63 9.7 0.3 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4140 PF13600.1 EMR71722.1 - 0.41 11.1 3.1 0.87 10.0 0.3 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FliD_N PF02465.13 EMR71722.1 - 0.73 10.2 5.4 0.15 12.4 0.4 2.3 2 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Med9 PF07544.8 EMR71722.1 - 4 7.2 8.8 13 5.5 0.9 3.2 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.5 EMR71722.1 - 6.2 6.9 7.3 2.3 8.3 1.2 2.5 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family XhlA PF10779.4 EMR71722.1 - 6.3 6.7 7.0 3.3 7.6 1.6 2.3 2 0 0 2 2 2 0 Haemolysin XhlA DNA_pol3_chi PF04364.8 EMR71723.1 - 0.027 14.3 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC DUF604 PF04646.7 EMR71724.1 - 4.5e-08 32.6 0.1 3.3e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF604 Fringe PF02434.11 EMR71724.1 - 2.8e-07 30.0 0.0 5.5e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Fringe-like NAD_binding_10 PF13460.1 EMR71725.1 - 0.0012 18.8 0.2 0.0017 18.3 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 EMR71725.1 - 0.0031 17.0 0.0 0.0054 16.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 EMR71725.1 - 0.009 15.9 2.9 0.016 15.1 1.7 1.9 1 1 1 2 2 2 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 EMR71725.1 - 0.025 14.3 0.1 0.043 13.6 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_18 PF12847.2 EMR71725.1 - 0.1 13.2 0.1 0.19 12.3 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF1446 PF07287.6 EMR71726.1 - 2.3e-123 411.2 0.0 2.7e-123 411.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) ADH_zinc_N PF00107.21 EMR71727.1 - 1.2e-23 83.1 0.0 1.7e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR71727.1 - 1.5e-19 69.7 3.8 2.8e-19 68.8 2.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 EMR71727.1 - 0.0003 19.9 0.1 0.0005 19.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 EMR71727.1 - 0.031 14.6 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain ThiF PF00899.16 EMR71727.1 - 0.044 13.6 1.4 0.084 12.7 1.0 1.4 1 0 0 1 1 1 0 ThiF family CMAS PF02353.15 EMR71727.1 - 0.044 12.8 0.1 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AlaDh_PNT_C PF01262.16 EMR71727.1 - 0.052 13.1 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_11 PF08241.7 EMR71727.1 - 0.095 13.1 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UbiD PF01977.11 EMR71728.1 - 3.5e-102 341.8 0.0 6.9e-102 340.9 0.0 1.4 1 1 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase MarR_2 PF12802.2 EMR71728.1 - 0.089 12.4 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 MarR family Aldedh PF00171.17 EMR71729.1 - 1e-154 515.3 0.0 1.2e-154 515.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMR71729.1 - 0.011 14.4 0.0 0.023 13.4 0.0 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) BRO1 PF03097.13 EMR71730.1 - 3.7e-111 371.5 0.0 7e-111 370.5 0.0 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EMR71730.1 - 7.6e-75 251.6 1.7 7.6e-75 251.6 1.2 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV PAT1 PF09770.4 EMR71730.1 - 0.32 9.1 42.0 0.56 8.3 29.1 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cep57_CLD_2 PF14197.1 EMR71730.1 - 7.8 6.5 23.3 0.37 10.7 2.8 4.3 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 Flavoprotein PF02441.14 EMR71731.1 - 1.7e-28 98.8 0.3 2.2e-28 98.4 0.2 1.1 1 0 0 1 1 1 1 Flavoprotein HMGL-like PF00682.14 EMR71732.1 - 1.1e-38 133.2 0.0 4.3e-38 131.2 0.0 1.8 1 1 0 1 1 1 1 HMGL-like NAD_binding_4 PF07993.7 EMR71733.1 - 3.1e-34 118.0 0.0 4.4e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EMR71733.1 - 2.3e-11 43.5 0.0 9.9e-11 41.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.23 EMR71733.1 - 7.5e-05 21.2 0.0 0.00015 20.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EMR71733.1 - 0.0002 21.5 0.0 0.00047 20.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EMR71733.1 - 0.0006 18.6 0.0 0.0046 15.6 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EMR71733.1 - 0.00076 18.4 0.1 0.03 13.2 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.5 EMR71733.1 - 0.0011 18.6 0.0 0.0051 16.5 0.0 2.1 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EMR71733.1 - 0.0014 18.5 0.3 0.0073 16.2 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EMR71733.1 - 0.13 11.0 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1077 PF06417.7 EMR71734.1 - 1.9e-56 188.8 3.3 2.3e-56 188.5 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.15 EMR71735.1 - 2.5e-108 362.7 6.2 2.7e-65 220.7 0.2 2.0 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 EMR71735.1 - 4.3e-16 58.9 3.7 2.4e-10 40.5 0.2 3.5 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.2 EMR71735.1 - 4e-12 46.3 2.2 2e-11 44.0 0.1 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EMR71735.1 - 1.5e-11 43.3 2.2 0.00077 19.3 0.0 4.6 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 EMR71735.1 - 1.7e-05 25.1 4.8 0.62 10.6 0.0 5.5 5 1 1 6 6 6 2 HEAT-like repeat Atx10homo_assoc PF09759.4 EMR71735.1 - 0.00015 21.4 0.2 3.1 7.5 0.0 4.1 4 1 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 EMR71735.1 - 0.00093 18.6 0.4 0.7 9.2 0.1 3.1 2 1 0 2 2 2 2 CLASP N terminal Arm PF00514.18 EMR71735.1 - 0.0079 15.9 0.2 2.1 8.3 0.0 3.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 EMR71735.1 - 0.11 12.3 0.4 5.8 6.8 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) Semialdhyde_dhC PF02774.13 EMR71736.1 - 8.8e-38 130.0 0.0 1.1e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EMR71736.1 - 0.00012 22.3 0.0 0.00058 20.1 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Alpha_GJ PF03229.8 EMR71737.1 - 0.22 11.8 7.9 0.4 11.0 5.5 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J Peptidase_M43 PF05572.8 EMR71738.1 - 2e-10 40.4 0.0 3.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EMR71738.1 - 8.5e-06 26.3 0.1 1.9e-05 25.1 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EMR71738.1 - 0.00023 21.1 0.1 0.0004 20.3 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EMR71738.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EMR71738.1 - 0.039 14.0 0.1 0.048 13.7 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Grp1_Fun34_YaaH PF01184.14 EMR71740.1 - 6.2e-29 100.8 0.4 7.9e-29 100.4 0.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family IBR PF01485.16 EMR71741.1 - 3.4e-14 52.4 36.3 3.5e-09 36.4 7.5 3.9 3 1 1 4 4 4 2 IBR domain DUF2732 PF10809.3 EMR71741.1 - 0.0017 17.8 2.8 0.0034 16.9 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2732) zf-RING_2 PF13639.1 EMR71741.1 - 0.0028 17.4 4.2 0.0028 17.4 2.9 3.6 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EMR71741.1 - 0.0084 16.1 4.5 0.0084 16.1 3.1 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EMR71741.1 - 0.019 14.6 1.1 0.019 14.6 0.8 3.3 3 0 0 3 3 3 0 RING-type zinc-finger TPR_10 PF13374.1 EMR71741.1 - 0.046 13.6 0.4 1.7 8.7 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat CorA PF01544.13 EMR71741.1 - 0.15 11.0 0.5 0.23 10.4 0.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Pal1 PF08316.6 EMR71742.1 - 3.6e-09 37.1 0.0 7.6e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Pal1 cell morphology protein Bromodomain PF00439.20 EMR71743.1 - 2.4e-28 97.8 0.0 3.3e-13 49.3 0.0 2.5 2 0 0 2 2 2 2 Bromodomain Ycf1 PF05758.7 EMR71743.1 - 8.2 3.9 8.3 9.9 3.7 5.8 1.2 1 0 0 1 1 1 0 Ycf1 Aldedh PF00171.17 EMR71744.1 - 4.9e-142 473.5 0.0 5.9e-142 473.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EMR71744.1 - 0.044 12.5 0.0 0.27 9.9 0.0 2.1 3 0 0 3 3 3 0 Acyl-CoA reductase (LuxC) CKS PF01111.14 EMR71745.1 - 5e-34 115.9 0.5 6.5e-34 115.5 0.4 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit G-patch PF01585.18 EMR71746.1 - 0.0066 16.2 1.8 0.021 14.5 0.3 2.6 2 1 0 2 2 2 1 G-patch domain RR_TM4-6 PF06459.7 EMR71746.1 - 2 8.2 8.1 2.8 7.7 5.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HVSL PF09749.4 EMR71747.1 - 1.5e-44 151.8 0.0 3.4e-34 117.9 0.0 2.3 1 1 1 2 2 2 2 Uncharacterised conserved protein TGFb_propeptide PF00688.13 EMR71747.1 - 0.0067 15.7 0.2 0.012 14.9 0.1 1.4 1 1 0 1 1 1 1 TGF-beta propeptide Ipi1_N PF12333.3 EMR71747.1 - 0.12 12.3 0.2 7.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation MBOAT PF03062.14 EMR71748.1 - 2.7e-39 135.1 18.1 2.7e-39 135.1 12.6 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family WD40 PF00400.27 EMR71749.1 - 2.4e-13 49.3 4.7 3.6e-05 23.4 0.1 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.6 EMR71749.1 - 1.8e-05 24.5 0.4 0.045 13.4 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EMR71749.1 - 0.00016 21.2 1.5 0.00082 18.8 1.0 2.3 1 1 0 1 1 1 1 PQQ-like domain Thg1C PF14413.1 EMR71750.1 - 1.5e-23 82.7 0.1 1.7e-23 82.5 0.1 1.0 1 0 0 1 1 1 1 Thg1 C terminal domain Baculo_PEP_C PF04513.7 EMR71752.1 - 0.057 13.2 1.4 0.27 11.0 0.4 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_Rpb1_1 PF04997.7 EMR71753.1 - 2.7e-114 381.9 0.0 4.8e-114 381.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EMR71753.1 - 3.1e-99 331.7 0.0 5.9e-99 330.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EMR71753.1 - 1.3e-70 236.6 0.0 2.5e-70 235.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EMR71753.1 - 4.7e-48 163.4 0.4 1e-47 162.3 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EMR71753.1 - 1.7e-46 157.7 0.0 5.9e-46 156.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EMR71753.1 - 1.8e-41 141.0 7.4 9.6e-41 138.6 5.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EMR71753.1 - 1.7e-35 121.0 0.0 3.7e-35 119.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 GXWXG PF14231.1 EMR71753.1 - 0.11 12.1 0.6 0.34 10.5 0.4 1.8 1 0 0 1 1 1 0 GXWXG protein CPSF_A PF03178.10 EMR71756.1 - 8.9e-80 268.1 0.0 1.1e-79 267.8 0.0 1.1 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 EMR71757.1 - 0.0021 16.2 0.0 0.0054 14.9 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Gln-synt_C PF00120.19 EMR71759.1 - 1.3e-62 211.3 0.0 1.6e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain MFS_1 PF07690.11 EMR71760.1 - 1.9e-34 118.9 19.7 2.1e-34 118.8 13.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2 PF04550.7 EMR71760.1 - 3.1 7.9 4.7 7.3 6.7 0.1 2.8 3 0 0 3 3 3 0 Phage holin family 2 DUF1932 PF09130.6 EMR71761.1 - 5.6e-21 74.0 0.2 1.2e-20 72.9 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.12 EMR71761.1 - 5.1e-08 33.2 0.2 1.3e-07 31.9 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EMR71761.1 - 2.5e-05 24.2 0.0 4.5e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 EMR71761.1 - 0.02 14.8 0.8 0.09 12.7 0.1 2.1 2 1 0 2 2 2 0 NADH(P)-binding CinA PF02464.12 EMR71761.1 - 0.043 13.2 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Competence-damaged protein 3HCDH_N PF02737.13 EMR71761.1 - 0.05 13.2 0.1 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Serglycin PF04360.7 EMR71761.1 - 0.058 13.1 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Serglycin 2-Hacid_dh_C PF02826.14 EMR71761.1 - 0.15 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAGAT PF03982.8 EMR71763.1 - 4.2e-94 314.5 0.0 5.4e-94 314.2 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase PI-PLC-X PF00388.14 EMR71764.1 - 6.8e-12 45.0 0.0 1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SnoaL_4 PF13577.1 EMR71765.1 - 3.4e-09 36.6 0.2 4.1e-09 36.4 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain Aminotran_5 PF00266.14 EMR71766.1 - 2.5e-21 75.8 0.0 1.2e-08 34.0 0.0 4.3 2 1 0 2 2 2 2 Aminotransferase class-V SWI-SNF_Ssr4 PF08549.5 EMR71767.1 - 1.2e-73 248.5 27.2 3.4e-72 243.7 18.9 2.0 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Sod_Cu PF00080.15 EMR71768.1 - 3.1e-14 53.3 0.1 4.2e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) 6PGD PF00393.14 EMR71769.1 - 3.7e-133 443.1 0.0 4.6e-133 442.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EMR71769.1 - 6e-52 175.7 0.0 8.9e-52 175.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EMR71769.1 - 0.01 15.9 0.0 0.03 14.3 0.0 1.8 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EMR71769.1 - 0.081 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EMR71769.1 - 0.14 11.2 0.0 0.37 9.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRM_1 PF00076.17 EMR71770.1 - 6.1e-16 57.8 0.0 9.2e-16 57.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR71770.1 - 9.5e-11 41.5 0.0 1.5e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR71770.1 - 1.1e-06 28.3 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pectate_lyase PF03211.8 EMR71771.1 - 1.6e-12 47.2 0.1 1.9e-12 47.0 0.1 1.0 1 0 0 1 1 1 1 Pectate lyase RRM_1 PF00076.17 EMR71772.1 - 2.4e-15 55.8 0.0 3.9e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR71772.1 - 3.4e-10 39.7 0.0 6.6e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR71772.1 - 0.00015 21.5 0.0 0.0003 20.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRP PF06011.7 EMR71773.1 - 5.8e-124 414.0 14.0 7.4e-124 413.6 9.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EMR71773.1 - 1.1e-37 129.2 3.5 2e-37 128.4 2.4 1.4 1 0 0 1 1 1 1 ML-like domain TMEM154 PF15102.1 EMR71773.1 - 0.99 9.0 3.4 10 5.8 0.2 2.4 2 0 0 2 2 2 0 TMEM154 protein family DUF2681 PF10883.3 EMR71773.1 - 3.4 7.9 4.7 8.5 6.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) TPT PF03151.11 EMR71774.1 - 2.6e-22 79.1 1.8 3.2e-22 78.8 1.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.15 EMR71774.1 - 0.0069 16.4 6.0 0.008 16.2 4.2 1.1 1 0 0 1 1 1 1 EamA-like transporter family DUF1510 PF07423.6 EMR71774.1 - 0.041 13.2 0.0 0.061 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) zf-C2H2 PF00096.21 EMR71775.1 - 2.9e-08 33.5 23.7 0.00032 20.8 0.3 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EMR71775.1 - 0.0039 17.4 29.0 0.0055 16.9 0.6 5.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EMR71775.1 - 0.089 12.7 0.0 0.089 12.7 0.0 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EMR71775.1 - 1.7 8.8 9.3 0.16 12.0 1.4 2.7 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF202 PF02656.10 EMR71776.1 - 0.0014 18.8 4.1 0.0017 18.5 1.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1376 PF07120.6 EMR71776.1 - 0.086 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) SNARE PF05739.14 EMR71778.1 - 5.7e-09 35.5 0.6 7.8e-09 35.0 0.4 1.2 1 0 0 1 1 1 1 SNARE domain DUF1421 PF07223.6 EMR71778.1 - 2.8 7.6 4.4 3.1 7.4 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) Sod_Fe_C PF02777.13 EMR71779.1 - 6.4e-41 138.4 0.1 1.3e-40 137.5 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EMR71779.1 - 1.3e-32 111.8 2.2 2.1e-32 111.1 1.5 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GCFC PF07842.7 EMR71780.1 - 1.5e-65 221.2 2.4 3.3e-65 220.1 1.7 1.6 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 EMR71780.1 - 1.1e-15 57.5 12.2 1.1e-15 57.5 8.5 3.3 3 0 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch PF01585.18 EMR71780.1 - 1.4e-14 53.5 0.8 4.7e-14 51.8 0.6 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EMR71780.1 - 3.2e-06 26.9 0.5 3.2e-06 26.9 0.3 3.6 3 1 1 4 4 4 1 DExH-box splicing factor binding site DUF4192 PF13830.1 EMR71780.1 - 0.0059 16.2 0.3 0.016 14.8 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4192) IncA PF04156.9 EMR71780.1 - 2.6 7.5 5.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 IncA protein Sld5 PF05916.6 EMR71781.1 - 2.9e-14 53.2 0.0 3.8e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Peptidase_M22 PF00814.20 EMR71781.1 - 0.037 13.5 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 Glycoprotease family Apc15p PF05841.6 EMR71782.1 - 2.3e-21 76.8 11.8 2.3e-21 76.8 8.2 2.2 2 0 0 2 2 2 1 Apc15p protein IBN_N PF03810.14 EMR71786.1 - 4.6e-13 48.8 0.4 8.3e-09 35.2 0.0 3.8 3 0 0 3 3 3 2 Importin-beta N-terminal domain Cse1 PF08506.5 EMR71786.1 - 2.6e-06 26.2 0.3 2.6e-05 22.9 0.0 2.2 1 1 0 2 2 2 1 Cse1 HEAT_2 PF13646.1 EMR71786.1 - 0.00089 19.4 1.7 1.1 9.6 0.0 3.5 2 1 1 3 3 3 3 HEAT repeats Xpo1 PF08389.7 EMR71786.1 - 0.0011 18.8 1.8 0.017 15.0 0.0 3.4 4 0 0 4 4 4 1 Exportin 1-like protein HEAT_EZ PF13513.1 EMR71786.1 - 0.89 10.1 4.1 16 6.1 0.0 4.6 4 0 0 4 4 4 0 HEAT-like repeat IMS PF00817.15 EMR71787.1 - 5.4e-33 113.8 0.0 7.7e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.3 EMR71787.1 - 0.00068 19.5 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Peptidase_S8 PF00082.17 EMR71788.1 - 5.1e-43 147.2 9.1 7.7e-43 146.6 6.3 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EMR71788.1 - 1.5e-12 47.9 0.1 2.9e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Amidohydro_1 PF01979.15 EMR71789.1 - 2.9e-27 96.2 0.3 4e-27 95.7 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMR71789.1 - 4.2e-17 63.0 0.2 1e-15 58.4 0.1 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMR71789.1 - 2e-08 33.9 0.9 1.2e-06 28.0 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EMR71789.1 - 2.3e-07 30.5 0.1 7.4e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase PAM2 PF07145.10 EMR71790.1 - 0.0041 16.5 10.4 0.8 9.3 0.0 3.8 3 0 0 3 3 3 3 Ataxin-2 C-terminal region Prominin PF05478.6 EMR71790.1 - 2.4 5.5 11.7 7.7 3.9 8.1 1.8 1 0 0 1 1 1 0 Prominin Cerato-platanin PF07249.7 EMR71791.1 - 4.3e-52 175.1 4.0 4.9e-52 174.9 2.8 1.0 1 0 0 1 1 1 1 Cerato-platanin Aldedh PF00171.17 EMR71792.1 - 1.2e-111 373.3 0.0 1.4e-111 373.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Hydrolase_like2 PF13246.1 EMR71793.1 - 7.7e-13 48.2 0.0 2.1e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 EMR71793.1 - 5.8e-12 45.1 0.1 2.2e-11 43.2 0.0 2.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EMR71793.1 - 5.8e-12 46.4 3.5 5.3e-10 40.0 2.4 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EMR71793.1 - 5.8e-12 46.1 0.1 2.2e-11 44.3 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMR71793.1 - 0.019 14.5 1.6 0.05 13.1 1.1 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glyco_tran_WbsX PF14307.1 EMR71794.1 - 4.3e-12 45.8 0.2 5.6e-12 45.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase WbsX SBF2 PF12335.3 EMR71794.1 - 0.023 14.0 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Myotubularin protein N-SET PF11764.3 EMR71794.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N XPA_C PF05181.7 EMR71795.1 - 1.7e-28 97.9 3.0 3.4e-28 96.9 2.1 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EMR71795.1 - 0.024 14.2 4.1 0.024 14.2 2.8 2.0 3 0 0 3 3 3 0 XPA protein N-terminal FYVE PF01363.16 EMR71795.1 - 0.04 13.8 0.9 0.49 10.3 0.3 2.3 2 0 0 2 2 2 0 FYVE zinc finger GRP PF07172.6 EMR71795.1 - 0.088 13.2 7.1 0.19 12.1 4.9 1.5 1 0 0 1 1 1 0 Glycine rich protein family DZR PF12773.2 EMR71795.1 - 0.13 12.0 3.5 2.8 7.8 1.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon YhfH PF14149.1 EMR71795.1 - 0.31 10.8 8.7 0.89 9.3 0.1 2.8 3 0 0 3 3 3 0 YhfH-like protein C1_1 PF00130.17 EMR71795.1 - 1.5 8.5 6.3 3.5 7.4 2.6 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) p450 PF00067.17 EMR71796.1 - 3.4e-79 266.5 0.0 4.7e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EMR71796.1 - 4.2e-34 117.9 0.0 6.9e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EMR71796.1 - 6.9e-26 90.9 0.0 1.3e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EMR71796.1 - 3.8e-12 46.7 0.0 9.2e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 EMR71796.1 - 0.022 14.6 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 NrdI Flavodoxin like FAD_binding_6 PF00970.19 EMR71796.1 - 0.036 14.2 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Flavodoxin_5 PF12724.2 EMR71796.1 - 0.049 13.6 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain AAA PF00004.24 EMR71797.1 - 4.6e-05 23.6 0.0 0.00015 21.9 0.0 1.8 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) RdRP PF05183.7 EMR71798.1 - 1.1e-112 377.6 0.8 6.1e-110 368.6 0.0 2.1 1 1 1 2 2 2 2 RNA dependent RNA polymerase DUF2452 PF10504.4 EMR71798.1 - 0.043 13.0 0.0 0.091 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Pho88 PF10032.4 EMR71799.1 - 3.4e-82 274.3 0.0 3.8e-82 274.1 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Aminotran_5 PF00266.14 EMR71800.1 - 6.8e-25 87.5 0.0 3.3e-24 85.3 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EMR71800.1 - 0.0062 15.5 0.0 0.015 14.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_6 PF12697.2 EMR71801.1 - 3e-25 89.4 0.3 4.7e-25 88.8 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR71801.1 - 4e-09 36.3 0.0 5.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR71801.1 - 6.6e-07 29.1 0.1 1.6e-06 27.9 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family EthD PF07110.6 EMR71801.1 - 0.0009 20.1 0.0 0.022 15.6 0.0 2.5 2 0 0 2 2 2 1 EthD domain Esterase PF00756.15 EMR71801.1 - 0.0041 16.5 0.0 0.0093 15.4 0.0 1.6 2 0 0 2 2 2 1 Putative esterase ABM PF03992.11 EMR71801.1 - 0.008 16.1 0.1 0.032 14.2 0.1 2.0 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase DUF4286 PF14114.1 EMR71801.1 - 0.025 14.8 0.1 9.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) DUF1479 PF07350.7 EMR71804.1 - 1.5e-148 494.7 0.0 1.9e-148 494.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Shikimate_dh_N PF08501.6 EMR71807.1 - 1.3e-22 79.6 0.0 2.3e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EMR71807.1 - 6.9e-15 55.3 0.0 1.1e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase E1-E2_ATPase PF00122.15 EMR71808.1 - 1.8e-56 190.7 2.1 1.8e-56 190.7 1.5 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EMR71808.1 - 9.2e-46 155.6 10.9 9.2e-46 155.6 7.6 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EMR71808.1 - 8.8e-31 107.9 0.1 3.3e-30 106.1 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EMR71808.1 - 5.4e-18 64.7 0.0 1.2e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EMR71808.1 - 1.3e-13 51.5 0.0 2.5e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EMR71808.1 - 1.1e-11 43.9 0.2 1.7e-10 40.1 0.0 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EMR71808.1 - 0.00031 20.4 0.1 0.0056 16.2 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.19 EMR71809.1 - 4.2e-93 312.3 15.2 2.1e-89 300.1 8.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter DUF4231 PF14015.1 EMR71809.1 - 0.04 13.8 0.1 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) RhodobacterPufX PF11511.3 EMR71809.1 - 0.34 10.3 0.1 0.34 10.3 0.0 2.6 2 0 0 2 2 2 0 Intrinsic membrane protein PufX adh_short PF00106.20 EMR71810.1 - 2.8e-25 89.1 1.0 4.1e-25 88.6 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR71810.1 - 1.9e-16 60.5 0.0 2.4e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR71810.1 - 3.3e-06 26.8 0.6 5.5e-06 26.1 0.4 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR71810.1 - 0.0064 15.9 0.1 0.0085 15.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR71810.1 - 0.012 15.6 0.1 0.021 14.8 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding Glyco_hydro_43 PF04616.9 EMR71811.1 - 2.7e-06 26.7 2.4 0.012 14.6 0.4 3.5 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.11 EMR71811.1 - 0.06 12.0 0.0 0.18 10.4 0.0 1.7 2 0 0 2 2 2 0 Levansucrase/Invertase Thioesterase PF00975.15 EMR71812.1 - 1.3e-30 107.2 0.0 3.5e-30 105.9 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain AMP-binding PF00501.23 EMR71812.1 - 1.2e-24 86.5 0.0 2.3e-24 85.5 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EMR71812.1 - 3.7e-07 30.3 0.2 9.1e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EMR71812.1 - 4.7e-05 23.3 0.1 0.00012 22.0 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family FCH PF00611.18 EMR71813.1 - 1.1e-22 80.0 0.0 1.1e-22 80.0 0.0 3.0 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EMR71813.1 - 2.4e-21 75.0 0.2 1.3e-11 43.9 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EMR71813.1 - 2.7e-16 58.6 0.1 4.1e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 EMR71813.1 - 8.6e-08 31.8 0.8 1.4e-07 31.0 0.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.6 EMR71813.1 - 4.3e-05 23.6 0.3 0.0057 16.8 0.0 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_2 PF07653.12 EMR71813.1 - 0.00019 20.8 0.1 0.59 9.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain IncA PF04156.9 EMR71813.1 - 0.034 13.7 6.6 0.083 12.4 1.2 2.5 2 0 0 2 2 2 0 IncA protein DUF2894 PF11445.3 EMR71813.1 - 0.23 11.7 6.8 0.05 13.8 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Spo12 PF05032.7 EMR71813.1 - 0.42 10.2 2.5 1.3 8.6 1.7 1.9 1 0 0 1 1 1 0 Spo12 family Ax_dynein_light PF10211.4 EMR71813.1 - 0.75 9.6 13.7 0.046 13.5 3.9 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain Tup_N PF08581.5 EMR71813.1 - 0.81 9.9 9.5 0.11 12.7 1.6 3.1 3 0 0 3 3 3 0 Tup N-terminal YlqD PF11068.3 EMR71813.1 - 3.3 7.7 13.0 9.2 6.3 1.4 2.9 2 1 1 3 3 3 0 YlqD protein Glyco_hydro_72 PF03198.9 EMR71814.1 - 4.7e-124 413.4 1.1 6e-124 413.1 0.8 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EMR71814.1 - 2e-05 23.9 0.1 0.00046 19.4 0.1 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DEAD PF00270.24 EMR71816.1 - 1e-32 112.9 0.6 1.8e-31 108.8 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR71816.1 - 4.7e-23 80.8 0.2 4.7e-23 80.8 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EMR71816.1 - 6.7e-05 22.5 0.1 0.03 14.0 0.0 3.2 2 1 1 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 EMR71816.1 - 0.0012 18.4 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMR71816.1 - 0.0051 16.9 1.0 0.26 11.4 0.4 2.8 2 1 0 2 2 2 1 AAA domain Helicase_C_2 PF13307.1 EMR71816.1 - 0.0059 16.5 0.0 0.018 15.0 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain Hexokinase_2 PF03727.11 EMR71816.1 - 0.071 12.2 0.0 4 6.5 0.0 2.4 2 0 0 2 2 2 0 Hexokinase DUF2075 PF09848.4 EMR71816.1 - 0.12 11.3 0.0 0.16 10.8 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SIR2 PF02146.12 EMR71817.1 - 6.8e-31 107.3 0.0 4e-11 42.9 0.0 3.1 3 0 0 3 3 3 3 Sir2 family TPP_enzyme_M PF00205.17 EMR71817.1 - 0.004 16.9 0.2 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DNA_ligase_OB PF03120.11 EMR71817.1 - 0.0041 16.7 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain But2 PF09792.4 EMR71818.1 - 0.00075 19.2 0.0 0.0018 18.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Ribosomal_S4 PF00163.14 EMR71819.1 - 7.7e-12 45.4 1.0 1.2e-11 44.7 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EMR71819.1 - 4.1e-11 42.1 0.0 9.5e-11 40.9 0.0 1.6 1 0 0 1 1 1 1 S4 domain SNF2_N PF00176.18 EMR71820.1 - 5.2e-50 169.9 0.0 7.2e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EMR71820.1 - 1.5e-22 79.2 0.6 4.1e-22 77.8 0.4 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EMR71820.1 - 7.3e-15 54.5 0.0 3.7e-14 52.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR71820.1 - 0.0026 17.6 0.0 0.15 11.8 0.0 3.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EMR71820.1 - 0.095 11.4 0.0 0.56 8.9 0.0 2.2 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 DUF2462 PF09495.5 EMR71821.1 - 4.1e-13 49.8 11.2 4.1e-13 49.8 7.8 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) RNase_H PF00075.19 EMR71822.1 - 6.4e-14 52.4 0.1 1.4e-13 51.2 0.1 1.5 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.1 EMR71822.1 - 2e-05 24.2 0.1 0.057 13.2 0.0 2.9 2 1 1 3 3 3 2 Reverse transcriptase-like PSRP-3_Ycf65 PF04839.8 EMR71822.1 - 0.012 15.6 0.1 0.045 13.8 0.0 1.9 2 0 0 2 2 2 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) TFIIA PF03153.8 EMR71823.1 - 1.3 8.8 13.2 2.4 7.9 9.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EMR71823.1 - 2.2 6.4 30.8 3.2 5.8 21.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lysis_S PF04971.7 EMR71824.1 - 0.036 13.7 0.0 0.16 11.7 0.0 2.1 1 0 0 1 1 1 0 Lysis protein S CFEM PF05730.6 EMR71825.1 - 0.0001 22.0 3.2 0.0002 21.1 2.2 1.5 1 1 0 1 1 1 1 CFEM domain CoA_transf_3 PF02515.12 EMR71827.1 - 1.5e-24 86.3 0.0 2.7e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III Sugar_tr PF00083.19 EMR71828.1 - 5.4e-106 354.8 25.5 6.3e-106 354.6 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR71828.1 - 6.4e-16 58.0 43.0 8.8e-15 54.2 22.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR71828.1 - 3.2e-07 28.9 10.1 3.2e-05 22.3 2.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) 3HCDH_N PF02737.13 EMR71829.1 - 2.4e-43 147.8 0.0 4.7e-42 143.6 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EMR71829.1 - 2e-09 37.7 0.0 4.1e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.14 EMR71829.1 - 0.00063 18.9 0.1 0.004 16.3 0.0 2.1 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EMR71829.1 - 0.0036 17.1 0.0 0.0062 16.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 EMR71829.1 - 0.036 14.3 0.1 0.45 10.8 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EMR71829.1 - 0.043 13.2 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Transketolase_N PF00456.16 EMR71830.1 - 5.9e-105 350.7 0.0 8.5e-105 350.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EMR71830.1 - 2.5e-33 115.0 0.0 5.7e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 EMR71830.1 - 2.2e-08 33.3 0.4 1.4e-06 27.4 0.3 3.1 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 EMR71830.1 - 1.7e-06 27.9 0.0 7e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 EMR71830.1 - 0.00028 20.5 1.3 0.0014 18.2 0.9 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EMR71830.1 - 0.026 13.2 0.0 0.059 12.0 0.0 1.5 2 0 0 2 2 2 0 Dehydrogenase E1 component TPP_enzyme_N PF02776.13 EMR71830.1 - 0.031 13.7 0.0 2.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Toprim_3 PF13362.1 EMR71830.1 - 0.094 12.9 0.0 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Toprim domain adh_short PF00106.20 EMR71831.1 - 1.3e-25 90.2 0.5 1.9e-25 89.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR71831.1 - 1.5e-20 74.0 0.0 1.9e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR71831.1 - 2.3e-14 53.4 0.2 5.2e-14 52.3 0.2 1.6 1 1 0 1 1 1 1 KR domain K-cyclin_vir_C PF09080.5 EMR71831.1 - 0.096 12.8 1.0 0.91 9.7 0.5 2.3 2 0 0 2 2 2 0 K cyclin, C terminal ADH_N PF08240.7 EMR71832.1 - 5.7e-21 74.3 0.1 1.1e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EMR71832.1 - 1.7e-10 40.5 0.1 3.6e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 EMR71832.1 - 0.074 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.1 EMR71832.1 - 0.096 12.7 0.1 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EMR71833.1 - 3.3e-29 102.3 0.0 6.2e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EMR71833.1 - 1.9e-20 72.5 0.0 2.3e-16 59.1 0.0 2.6 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EMR71833.1 - 1.5e-10 40.9 0.0 5.4e-10 39.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EMR71833.1 - 3e-08 32.9 0.2 7e-06 25.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EMR71833.1 - 2e-07 31.1 0.0 1.8e-05 24.7 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR71833.1 - 0.00019 21.2 0.1 0.016 14.9 0.0 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EMR71833.1 - 0.00024 20.1 0.0 0.2 10.4 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EMR71833.1 - 0.0036 17.3 0.3 3 7.9 0.0 3.1 4 0 0 4 4 4 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EMR71833.1 - 0.16 11.0 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EMR71833.1 - 0.32 9.8 0.0 0.32 9.8 0.0 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EMR71834.1 - 6.2e-33 113.9 0.0 9.3e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EMR71834.1 - 2.9e-15 56.4 0.0 6.9e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EMR71834.1 - 2.6e-05 23.9 0.0 4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EMR71834.1 - 0.00025 20.8 0.0 0.0006 19.6 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase SGL PF08450.7 EMR71834.1 - 0.0012 18.2 0.0 0.036 13.4 0.0 2.6 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Ldl_recept_b PF00058.12 EMR71834.1 - 0.0036 17.5 2.1 8.9 6.7 0.0 5.5 5 1 0 5 5 5 1 Low-density lipoprotein receptor repeat class B NHL PF01436.16 EMR71834.1 - 0.059 13.3 0.0 3.3 7.8 0.0 3.5 4 0 0 4 4 4 0 NHL repeat 2-Hacid_dh_C PF02826.14 EMR71834.1 - 0.064 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 EMR71836.1 - 9.2e-07 28.9 0.1 1.7e-06 28.0 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase DUF460 PF04312.8 EMR71836.1 - 0.025 14.0 0.1 0.049 13.1 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF460) KR PF08659.5 EMR71836.1 - 0.04 13.5 0.0 0.088 12.4 0.0 1.5 1 1 0 1 1 1 0 KR domain p450 PF00067.17 EMR71837.1 - 2.7e-57 194.3 0.0 3.3e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FTA2 PF13095.1 EMR71838.1 - 1.9e-18 66.8 0.0 2.1e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 PNPase_C PF12111.3 EMR71839.1 - 0.0024 17.0 3.0 0.0024 17.0 2.1 2.9 3 0 0 3 3 3 1 Polyribonucleotide phosphorylase C terminal Amnionless PF14828.1 EMR71839.1 - 0.061 11.8 0.0 0.09 11.2 0.0 1.2 1 0 0 1 1 1 0 Amnionless AIF_C PF14721.1 EMR71839.1 - 1 9.5 3.7 4.8 7.4 0.0 2.4 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Tim54 PF11711.3 EMR71839.1 - 6.2 5.3 6.0 10 4.5 4.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Glyco_transf_22 PF03901.12 EMR71840.1 - 1.2e-85 288.0 17.0 1.4e-85 287.8 11.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.9 EMR71841.1 - 8.3e-39 132.5 2.9 9.5e-39 132.3 0.0 2.6 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region FXR1P_C PF12235.3 EMR71841.1 - 3.2 7.8 31.5 0.15 12.1 3.1 3.6 3 0 0 3 3 3 0 Fragile X-related 1 protein C terminal HET PF06985.6 EMR71842.1 - 5.3e-26 91.4 0.0 8.5e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.13 EMR71843.1 - 9e-07 28.0 3.1 9e-07 28.0 2.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Dicty_CAR PF05462.6 EMR71844.1 - 1.4e-12 47.1 8.8 1.4e-12 47.1 6.1 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EMR71844.1 - 6.5e-06 25.8 12.2 1.4e-05 24.7 8.5 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.4 EMR71844.1 - 0.034 13.2 6.6 0.056 12.5 4.6 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Ras PF00071.17 EMR71845.1 - 4.8e-57 191.8 0.0 5.6e-57 191.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EMR71845.1 - 1.7e-18 67.2 0.0 2.6e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EMR71845.1 - 1.9e-13 50.0 0.0 2.2e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EMR71845.1 - 4.7e-08 32.9 0.0 6.8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EMR71845.1 - 5.1e-08 32.3 0.0 6.4e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EMR71845.1 - 1.6e-07 30.9 0.0 3.3e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMR71845.1 - 0.0006 19.9 0.0 0.0015 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EMR71845.1 - 0.0011 18.2 0.1 0.0021 17.2 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 EMR71845.1 - 0.0011 18.7 0.0 0.0045 16.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SRPRB PF09439.5 EMR71845.1 - 0.0021 17.2 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EMR71845.1 - 0.0026 17.3 0.2 0.094 12.2 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EMR71845.1 - 0.0029 17.0 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EMR71845.1 - 0.0031 17.5 0.0 0.01 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 EMR71845.1 - 0.0049 16.4 0.1 0.0088 15.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EMR71845.1 - 0.0059 16.3 0.2 0.01 15.5 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 EMR71845.1 - 0.008 15.6 0.2 0.018 14.4 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain Septin PF00735.13 EMR71845.1 - 0.01 14.8 0.0 0.025 13.5 0.0 1.7 2 0 0 2 2 2 0 Septin cobW PF02492.14 EMR71845.1 - 0.015 14.7 0.1 0.11 11.8 0.0 2.0 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EMR71845.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 NTPase MobB PF03205.9 EMR71845.1 - 0.022 14.4 0.1 0.056 13.1 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EMR71845.1 - 0.082 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Fibrillarin PF01269.12 EMR71846.1 - 3.2e-104 346.8 0.0 4e-104 346.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EMR71846.1 - 0.00032 20.2 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit zf-NADH-PPase PF09297.6 EMR71847.1 - 0.077 12.5 0.2 0.17 11.4 0.2 1.6 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DUF1537 PF07005.6 EMR71848.1 - 3.3e-25 89.0 2.4 4.8e-25 88.5 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF1537 FERM_C PF09380.5 EMR71850.1 - 0.038 14.2 0.0 0.085 13.0 0.0 1.6 1 0 0 1 1 1 0 FERM C-terminal PH-like domain Cyclase PF04199.8 EMR71851.1 - 1e-13 51.3 0.0 1.5e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase MFS_1 PF07690.11 EMR71852.1 - 3.4e-21 75.3 21.7 4e-21 75.1 13.9 1.9 2 1 1 3 3 3 2 Major Facilitator Superfamily SET PF00856.23 EMR71853.1 - 6e-13 49.4 0.0 1.4e-07 31.9 0.0 2.1 2 0 0 2 2 2 2 SET domain SAF PF08666.7 EMR71853.1 - 0.028 14.8 0.1 4.5 7.7 0.1 2.3 2 0 0 2 2 2 0 SAF domain Heme_oxygenase PF01126.15 EMR71855.1 - 2.7e-12 46.7 0.0 2.1e-11 43.8 0.0 2.2 2 1 0 2 2 2 1 Heme oxygenase Ribosomal_60s PF00428.14 EMR71855.1 - 2.5 8.5 9.8 7.1 7.1 6.8 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein SAF PF08666.7 EMR71856.1 - 3.5e-07 30.5 0.0 6.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 SAF domain GFO_IDH_MocA PF01408.17 EMR71856.1 - 4.8e-06 27.0 0.0 1.6e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EMR71856.1 - 0.00014 22.2 0.0 0.00038 20.8 0.0 1.8 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 EMR71856.1 - 0.013 15.4 0.2 0.036 14.0 0.0 1.8 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Ribosomal_L22 PF00237.14 EMR71858.1 - 7.4e-34 115.8 0.1 9.9e-34 115.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e EamA PF00892.15 EMR71859.1 - 6.5e-08 32.6 29.3 5.4e-06 26.4 2.5 3.1 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 EMR71859.1 - 1.2e-06 27.7 7.9 1.2e-06 27.7 5.5 1.6 2 0 0 2 2 2 1 UAA transporter family EmrE PF13536.1 EMR71859.1 - 7.4e-06 26.1 4.8 7.4e-06 26.1 3.3 3.3 3 2 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 EMR71859.1 - 8.5e-06 24.8 8.8 8.5e-06 24.8 6.1 1.8 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 EMR71859.1 - 1.5e-05 24.7 20.7 0.00014 21.4 0.6 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family Serglycin PF04360.7 EMR71859.1 - 0.088 12.5 0.4 0.19 11.4 0.3 1.5 1 0 0 1 1 1 0 Serglycin GPI-anchored PF10342.4 EMR71860.1 - 8.9e-08 32.5 0.8 4e-07 30.4 0.6 1.9 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FMO-like PF00743.14 EMR71861.1 - 3.6e-25 88.1 0.3 8.1e-15 54.0 0.1 5.0 4 1 0 4 4 4 4 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMR71861.1 - 1.2e-07 31.9 0.0 1.2e-06 28.7 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EMR71861.1 - 1.1e-05 24.5 0.0 0.00089 18.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMR71861.1 - 0.00025 20.8 4.7 0.17 11.6 0.1 4.1 4 1 1 5 5 5 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMR71861.1 - 0.0023 17.8 0.0 0.35 10.7 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ANTH PF07651.11 EMR71861.1 - 0.14 10.8 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 ANTH domain Shikimate_DH PF01488.15 EMR71861.1 - 0.17 12.0 0.1 1.8 8.6 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase peroxidase PF00141.18 EMR71862.1 - 8.5e-19 67.9 0.2 1.4e-18 67.2 0.1 1.2 1 0 0 1 1 1 1 Peroxidase SecY PF00344.15 EMR71863.1 - 1.3e-96 323.5 10.0 1.7e-96 323.1 7.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EMR71863.1 - 1.1e-18 66.4 0.2 7.2e-18 63.8 0.2 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p ABC_tran PF00005.22 EMR71864.1 - 5.8e-53 178.8 0.0 1.6e-30 106.1 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMR71864.1 - 1.2e-42 146.2 21.2 6.7e-25 88.0 6.5 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EMR71864.1 - 3.4e-09 36.2 0.5 0.025 13.8 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMR71864.1 - 9.1e-09 35.9 0.1 4.5e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EMR71864.1 - 9.6e-09 35.6 0.0 0.31 10.9 0.0 4.5 3 1 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EMR71864.1 - 4.4e-06 26.3 0.0 0.022 14.1 0.0 2.9 3 0 0 3 3 3 2 AAA-like domain AAA_29 PF13555.1 EMR71864.1 - 6e-06 25.6 0.2 0.052 13.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EMR71864.1 - 9e-06 25.2 0.0 0.11 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EMR71864.1 - 0.00021 20.2 0.1 0.049 12.5 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 EMR71864.1 - 0.00027 20.1 0.0 0.27 10.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EMR71864.1 - 0.00046 19.3 0.5 0.31 10.0 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.1 EMR71864.1 - 0.00094 19.2 0.2 0.58 10.1 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EMR71864.1 - 0.00099 18.6 0.1 0.52 9.7 0.1 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 EMR71864.1 - 0.0019 18.9 0.1 2.1 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EMR71864.1 - 0.0027 17.6 0.0 0.17 11.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EMR71864.1 - 0.0028 18.1 0.2 4.6 7.7 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EMR71864.1 - 0.0031 17.6 0.1 1.4 9.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 EMR71864.1 - 0.0036 17.0 0.2 5 6.8 0.0 3.3 4 0 0 4 4 3 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EMR71864.1 - 0.0041 16.9 3.4 0.033 14.0 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF87 IstB_IS21 PF01695.12 EMR71864.1 - 0.012 15.0 0.1 5.4 6.3 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.1 EMR71864.1 - 0.025 14.9 0.0 5.2 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EMR71864.1 - 0.041 12.4 0.8 3.1 6.3 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.17 EMR71864.1 - 0.053 13.6 0.1 10 6.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ResIII PF04851.10 EMR71864.1 - 0.067 13.0 0.1 17 5.1 0.1 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EMR71864.1 - 0.072 12.6 0.3 16 5.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EMR71864.1 - 0.11 12.1 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 EMR71864.1 - 0.12 12.6 0.2 5.7 7.1 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EMR71864.1 - 0.14 11.9 0.5 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Dynamin family DUF815 PF05673.8 EMR71864.1 - 0.16 10.8 0.1 0.85 8.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) GPI-anchored PF10342.4 EMR71865.1 - 2e-07 31.4 0.1 2.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_43 PF04616.9 EMR71866.1 - 6.5e-21 74.6 0.9 1.9e-20 73.1 0.6 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EMR71866.1 - 0.0032 16.8 0.1 0.16 11.2 0.0 2.5 2 1 1 3 3 3 1 Glycosyl hydrolases family 32 N-terminal domain Ank_2 PF12796.2 EMR71867.1 - 7.9e-33 112.6 0.7 2.1e-10 40.7 0.0 5.8 2 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 EMR71867.1 - 2.8e-31 105.7 10.1 3.6e-06 26.5 0.3 7.8 7 1 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EMR71867.1 - 3.1e-24 84.8 5.6 3.7e-08 33.6 0.1 7.0 5 2 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR71867.1 - 9.4e-20 68.7 8.0 0.00019 21.3 0.1 9.6 8 2 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 EMR71867.1 - 1.7e-18 66.1 11.0 2.7e-08 33.8 0.0 7.2 5 3 2 7 7 7 4 Ankyrin repeats (many copies) adh_short PF00106.20 EMR71868.1 - 6.3e-16 58.7 0.3 1.9e-15 57.1 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 EMR71868.1 - 0.0005 19.7 0.7 0.0015 18.2 0.6 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 EMR71868.1 - 0.00074 19.3 0.0 0.0013 18.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR71868.1 - 0.00091 18.7 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EMR71868.1 - 0.0011 18.6 0.9 0.78 9.3 0.0 2.8 2 1 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 EMR71868.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding Metallophos PF00149.23 EMR71869.1 - 7.5e-05 22.2 0.4 0.00023 20.6 0.3 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EMR71869.1 - 0.02 14.7 0.0 0.04 13.7 0.0 1.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DnaJ PF00226.26 EMR71871.1 - 1.6e-20 72.5 2.5 5.3e-20 70.9 1.7 1.9 1 0 0 1 1 1 1 DnaJ domain Dioxygenase_C PF00775.16 EMR71872.1 - 1.3e-07 31.0 0.2 1e-05 24.8 0.0 2.6 2 1 0 2 2 2 2 Dioxygenase IPPT PF01715.12 EMR71873.1 - 3.4e-55 186.8 0.3 5.2e-55 186.2 0.2 1.2 1 0 0 1 1 1 1 IPP transferase DUF3505 PF12013.3 EMR71873.1 - 0.017 15.3 2.0 0.093 12.9 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) zf-C2H2_jaz PF12171.3 EMR71873.1 - 5.8 7.1 6.3 0.35 11.0 0.4 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding MBOAT PF03062.14 EMR71874.1 - 3.4e-30 105.2 27.8 4.2e-29 101.7 19.2 2.2 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF2207 PF09972.4 EMR71874.1 - 0.099 11.2 2.7 0.25 9.8 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Ank_2 PF12796.2 EMR71876.1 - 2.5e-26 91.8 0.1 1e-17 64.2 0.2 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMR71876.1 - 1.6e-18 65.4 4.9 8.8e-08 31.5 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EMR71876.1 - 6.3e-16 58.0 3.5 4e-07 30.0 0.1 5.4 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR71876.1 - 1.3e-13 51.0 0.0 6.2e-05 23.3 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR71876.1 - 2.1e-13 49.0 0.1 0.00022 21.1 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat DUF2428 PF10350.4 EMR71877.1 - 4e-50 170.2 0.1 8.9e-50 169.0 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EMR71877.1 - 3.4e-06 26.6 18.7 0.83 9.9 0.3 7.8 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 EMR71877.1 - 0.0012 19.1 8.0 0.3 11.3 0.2 4.9 4 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EMR71877.1 - 0.27 11.7 16.2 0.21 12.1 0.4 5.8 5 1 1 6 6 6 0 HEAT-like repeat DUF1330 PF07045.6 EMR71879.1 - 0.62 9.9 4.0 2.4 8.0 2.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1330) TGS PF02824.16 EMR71880.1 - 3.4e-18 65.2 0.0 6.3e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EMR71880.1 - 1.9e-17 63.2 0.0 4.7e-17 62.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMR71880.1 - 6.4e-09 35.2 0.1 3.1e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EMR71880.1 - 6.1e-05 22.5 0.1 0.8 9.1 0.0 3.7 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EMR71880.1 - 0.00015 21.5 0.1 0.038 13.7 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 EMR71880.1 - 0.016 14.0 0.3 0.052 12.3 0.1 1.9 2 0 0 2 2 2 0 ArgK protein Arf PF00025.16 EMR71880.1 - 0.024 13.8 0.1 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.1 EMR71880.1 - 0.1 12.7 0.1 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF211 PF02680.9 EMR71880.1 - 0.11 12.3 0.2 0.33 10.7 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Methyltransf_23 PF13489.1 EMR71882.1 - 2.1e-09 37.2 0.0 3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR71882.1 - 0.00091 19.7 0.0 0.034 14.7 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR71882.1 - 0.0037 17.7 0.0 0.026 14.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR71882.1 - 0.033 14.6 0.0 0.062 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF3074 PF11274.3 EMR71883.1 - 3.7e-32 111.4 9.0 2e-23 82.9 0.1 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3074) Tim17 PF02466.14 EMR71884.1 - 6.5e-24 84.4 4.3 8.7e-24 83.9 3.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family 5TM-5TMR_LYT PF07694.7 EMR71884.1 - 0.054 12.8 0.3 0.091 12.0 0.2 1.3 1 0 0 1 1 1 0 5TMR of 5TMR-LYT PS-DH PF14765.1 EMR71885.1 - 3.8e-64 216.6 0.6 6e-64 216.0 0.4 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 EMR71885.1 - 2.3e-62 210.7 0.1 6.3e-62 209.3 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMR71885.1 - 2.6e-56 191.2 0.0 5.1e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EMR71885.1 - 1e-55 188.1 0.1 3.2e-55 186.5 0.0 2.0 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EMR71885.1 - 1.7e-40 138.7 0.1 5.8e-40 136.9 0.0 2.1 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMR71885.1 - 4.4e-38 129.7 0.0 9.2e-38 128.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EMR71885.1 - 5.4e-18 64.7 0.0 3.4e-15 55.7 0.0 3.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EMR71885.1 - 3.7e-17 62.6 0.0 2.8e-16 59.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR71885.1 - 1.2e-12 47.8 0.0 3.2e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EMR71885.1 - 3.7e-08 33.1 0.0 1.4e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 EMR71885.1 - 6.7e-08 33.1 0.0 2.4e-07 31.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EMR71885.1 - 1.2e-07 32.6 0.0 4.7e-07 30.7 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EMR71885.1 - 1.7e-07 30.9 0.0 5.1e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EMR71885.1 - 4.9e-07 29.9 0.4 1.5e-06 28.3 0.0 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EMR71885.1 - 3.8e-06 27.2 0.0 1.4e-05 25.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain NodS PF05401.6 EMR71885.1 - 0.02 14.3 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_PK PF05891.7 EMR71885.1 - 0.2 10.9 0.0 0.44 9.8 0.0 1.5 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase SH3_1 PF00018.23 EMR71887.1 - 0.00037 19.8 0.0 0.0009 18.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Caldesmon PF02029.10 EMR71887.1 - 2.6 6.3 33.0 0.0078 14.6 16.1 1.6 2 0 0 2 2 2 0 Caldesmon HTH_Tnp_Tc5 PF03221.11 EMR71888.1 - 4.3e-10 39.2 0.0 1.2e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_Tnp_4 PF13613.1 EMR71888.1 - 0.0054 16.2 0.1 0.013 14.9 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease LysM PF01476.15 EMR71889.1 - 0.00043 20.1 0.0 0.00072 19.4 0.0 1.4 1 0 0 1 1 1 1 LysM domain Baculo_IE-1 PF05290.6 EMR71889.1 - 0.009 15.7 1.6 0.014 15.1 1.1 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) UBA_4 PF14555.1 EMR71889.1 - 0.027 13.9 0.4 0.051 13.1 0.2 1.4 1 0 0 1 1 1 0 UBA-like domain DUF605 PF04652.11 EMR71889.1 - 6.4 6.0 11.1 8.4 5.6 7.7 1.1 1 0 0 1 1 1 0 Vta1 like Methyltransf_16 PF10294.4 EMR71890.1 - 3.7e-09 36.2 0.0 9.3e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase EF-hand_7 PF13499.1 EMR71892.1 - 1.2e-28 99.0 11.6 5.1e-14 52.1 0.6 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EMR71892.1 - 1.4e-24 83.4 13.4 3.8e-08 32.0 0.2 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EMR71892.1 - 7.7e-24 81.3 4.2 5.4e-06 25.8 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EMR71892.1 - 6.5e-18 63.1 14.8 2.5e-05 23.3 0.0 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 EMR71892.1 - 8e-15 54.1 13.3 5.2e-05 22.7 1.1 4.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EMR71892.1 - 1.8e-09 37.2 8.1 0.0048 16.6 0.2 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EMR71892.1 - 5.7e-05 22.9 0.4 0.02 14.7 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EMR71892.1 - 0.00025 21.0 2.1 0.45 10.5 0.1 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EMR71892.1 - 0.0028 17.2 3.4 0.32 10.7 0.0 4.0 4 0 0 4 4 4 1 EF hand Toprim PF01751.17 EMR71892.1 - 0.0091 15.9 0.0 3 7.8 0.0 2.3 1 1 0 2 2 2 2 Toprim domain DUF1679 PF07914.6 EMR71892.1 - 0.03 12.9 0.3 2.7 6.5 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_2 PF09068.6 EMR71892.1 - 0.034 14.2 0.2 4.7 7.2 0.0 3.1 3 1 1 4 4 4 0 EF hand adh_short PF00106.20 EMR71895.1 - 3e-15 56.5 1.4 1.1e-14 54.7 1.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR71895.1 - 1.2e-09 38.2 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EMR71895.1 - 1.8e-05 24.0 0.0 2.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR71895.1 - 0.0014 18.6 0.9 0.004 17.1 0.0 2.1 2 1 1 3 3 3 1 NADH(P)-binding DUF1776 PF08643.5 EMR71895.1 - 0.0017 17.5 0.0 0.0099 15.0 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) TrkA_N PF02254.13 EMR71895.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EMR71895.1 - 0.024 14.0 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 EMR71895.1 - 0.031 14.0 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EMR71895.1 - 0.045 12.8 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain QRPTase_C PF01729.14 EMR71895.1 - 0.063 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain AMP-binding PF00501.23 EMR71896.1 - 1.9e-79 267.0 0.0 2.8e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CDC45 PF02724.9 EMR71897.1 - 6.8e-98 328.3 22.1 7.8e-97 324.8 15.3 2.8 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.7 EMR71897.1 - 0.0032 17.2 9.1 0.0032 17.2 6.3 1.7 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein FAM60A PF15396.1 EMR71897.1 - 0.034 13.8 1.9 0.056 13.1 1.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Nop25 PF09805.4 EMR71897.1 - 0.067 13.2 16.3 0.14 12.2 11.3 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) BUD22 PF09073.5 EMR71897.1 - 0.14 11.2 16.8 0.21 10.6 11.6 1.2 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.5 EMR71897.1 - 0.2 11.6 13.3 0.18 11.8 8.4 1.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF2201_N PF13203.1 EMR71897.1 - 0.91 8.6 7.9 1.8 7.6 5.5 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2457 PF10446.4 EMR71897.1 - 5 5.7 17.9 9.2 4.8 12.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TT_ORF2 PF02957.10 EMR71897.1 - 9.6 6.9 11.0 23 5.7 7.6 1.6 1 0 0 1 1 1 0 TT viral ORF2 PUF PF00806.14 EMR71898.1 - 2e-60 196.9 11.0 8.7e-09 34.3 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TylF PF05711.6 EMR71898.1 - 0.12 11.4 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Cellulase PF00150.13 EMR71899.1 - 6.9e-16 58.2 1.6 1e-15 57.7 1.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DAO PF01266.19 EMR71900.1 - 8.1e-37 126.9 0.0 9.7e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR71900.1 - 9.2e-08 32.0 0.0 2.8e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR71900.1 - 0.00022 21.1 0.1 0.0036 17.1 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR71900.1 - 0.00053 19.7 0.0 0.08 12.7 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EMR71900.1 - 0.00097 19.2 0.0 0.018 15.1 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EMR71900.1 - 0.0013 17.8 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EMR71900.1 - 0.0035 17.4 0.0 0.0065 16.5 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR71900.1 - 0.0048 15.7 0.2 0.054 12.3 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EMR71900.1 - 0.0058 16.2 0.1 0.2 11.2 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EMR71900.1 - 0.0087 16.4 0.0 0.14 12.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR71900.1 - 0.019 13.8 0.2 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Ldh_1_N PF00056.18 EMR71900.1 - 0.026 14.3 0.0 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EMR71900.1 - 0.051 13.8 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding adh_short PF00106.20 EMR71900.1 - 0.056 13.3 0.2 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase ApbA PF02558.11 EMR71900.1 - 0.071 12.5 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EMR71900.1 - 0.1 12.6 0.0 0.77 9.7 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain SOG2 PF10428.4 EMR71901.1 - 0.0049 15.5 3.8 0.009 14.7 2.6 1.5 1 1 0 1 1 1 1 RAM signalling pathway protein DUF1987 PF09345.5 EMR71901.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) PSP1 PF04468.7 EMR71902.1 - 1.8e-31 107.9 0.6 3.2e-31 107.1 0.4 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.6 EMR71903.1 - 6e-30 102.7 0.0 1.9e-29 101.0 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EMR71903.1 - 7.1e-23 80.1 0.1 1.1e-22 79.5 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Abhydrolase_6 PF12697.2 EMR71904.1 - 1.6e-11 44.5 0.2 2.2e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR71904.1 - 4.9e-05 23.1 0.1 6.5e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR71904.1 - 0.00073 19.1 0.0 0.041 13.4 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EMR71904.1 - 0.0022 17.6 0.2 0.0051 16.4 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein DUF900 PF05990.7 EMR71904.1 - 0.011 15.0 0.0 0.028 13.7 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_8 PF06259.7 EMR71904.1 - 0.041 13.3 0.2 0.066 12.7 0.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase p450 PF00067.17 EMR71906.1 - 1.2e-49 169.1 0.0 1.1e-48 165.9 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 RNA_pol_Rpb2_6 PF00562.23 EMR71907.1 - 4.1e-117 391.1 0.0 6.5e-117 390.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EMR71907.1 - 5.2e-50 169.2 0.1 1.3e-49 167.9 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EMR71907.1 - 5.5e-30 103.4 0.3 1.5e-29 102.0 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EMR71907.1 - 5.4e-26 91.1 0.0 1.6e-25 89.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EMR71907.1 - 4.7e-21 74.3 0.1 1.3e-20 72.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EMR71907.1 - 3.2e-20 71.6 0.0 6.3e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EMR71907.1 - 6.1e-13 48.5 0.3 1.3e-12 47.4 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Herpeto_peptide PF14409.1 EMR71908.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Herpetosiphon DUF883 PF05957.8 EMR71908.1 - 7.3 7.0 6.5 7.1 7.1 0.9 2.8 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) zf-HIT PF04438.11 EMR71909.1 - 3.7e-05 23.2 7.5 5.1e-05 22.8 5.2 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-Mss51 PF13824.1 EMR71909.1 - 0.43 10.4 3.3 0.78 9.6 2.3 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Amidohydro_1 PF01979.15 EMR71910.1 - 5.8e-31 108.3 0.1 6.9e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMR71910.1 - 2.7e-16 60.4 6.3 4e-10 40.1 0.4 2.5 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EMR71910.1 - 2.1e-11 43.4 0.0 7e-11 41.7 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMR71910.1 - 8.7e-10 38.3 3.3 6.6e-08 32.1 0.3 2.3 2 0 0 2 2 2 2 Amidohydrolase family Chorion_3 PF05387.6 EMR71910.1 - 0.067 12.6 2.7 0.12 11.8 1.9 1.4 1 0 0 1 1 1 0 Chorion family 3 Rad51 PF08423.6 EMR71911.1 - 4.1e-16 58.6 0.0 1.1e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.1 EMR71911.1 - 6.4e-09 35.4 0.1 2.6e-08 33.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 EMR71911.1 - 6.1e-07 28.7 0.0 1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KaiC RecA PF00154.16 EMR71911.1 - 2.8e-06 26.6 0.1 7.4e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 recA bacterial DNA recombination protein Serglycin PF04360.7 EMR71911.1 - 0.0088 15.7 0.5 0.022 14.5 0.4 1.6 1 0 0 1 1 1 1 Serglycin ABC_tran PF00005.22 EMR71911.1 - 0.012 15.9 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EMR71911.1 - 0.02 14.8 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 EMR71911.1 - 0.025 13.5 0.0 0.048 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF3246 PF11596.3 EMR71911.1 - 0.055 12.7 0.2 0.13 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) MRI PF15325.1 EMR71911.1 - 9.9 7.1 10.7 2.6 9.0 0.3 3.1 3 0 0 3 3 3 0 Modulator of retrovirus infection SKG6 PF08693.5 EMR71912.1 - 0.00027 20.1 0.5 0.00061 19.0 0.4 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EMR71912.1 - 0.012 16.0 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain YajC PF02699.10 EMR71912.1 - 0.013 15.1 0.4 0.025 14.2 0.3 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Alpha_GJ PF03229.8 EMR71912.1 - 0.019 15.3 3.0 0.019 15.3 2.1 2.5 3 0 0 3 3 3 0 Alphavirus glycoprotein J DUF533 PF04391.7 EMR71912.1 - 0.021 14.1 0.8 0.037 13.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Syndecan PF01034.15 EMR71912.1 - 0.06 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain DUF1191 PF06697.7 EMR71912.1 - 0.079 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Adeno_E3_CR2 PF02439.10 EMR71912.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 IncA PF04156.9 EMR71912.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 IncA protein EHN PF06441.7 EMR71914.1 - 1.7e-30 105.2 0.1 2.6e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EMR71914.1 - 3.1e-08 33.7 0.0 6.9e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR71914.1 - 6.3e-05 22.6 0.1 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 EMR71915.1 - 6.7e-27 94.1 61.8 3.5e-25 88.4 39.3 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR71915.1 - 8.2e-13 47.7 0.8 8.2e-13 47.7 0.5 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter PNP_UDP_1 PF01048.15 EMR71916.1 - 3.1e-15 55.8 0.6 5.6e-15 54.9 0.4 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily APH PF01636.18 EMR71917.1 - 1.5e-06 28.1 0.3 3.8e-06 26.8 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EMR71917.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EMR71917.1 - 0.099 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) p450 PF00067.17 EMR71918.1 - 3.5e-42 144.5 0.0 4.2e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nop53 PF07767.6 EMR71919.1 - 0.047 12.6 3.9 0.063 12.2 2.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Myc_N PF01056.13 EMR71919.1 - 0.14 11.3 1.7 0.19 10.8 1.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region fn3 PF00041.16 EMR71920.1 - 0.036 14.1 0.1 0.13 12.4 0.1 2.0 1 0 0 1 1 1 0 Fibronectin type III domain adh_short PF00106.20 EMR71922.1 - 2.2e-25 89.4 2.0 2.9e-25 89.0 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR71922.1 - 9.2e-23 81.2 0.1 1.1e-22 81.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR71922.1 - 1.2e-09 38.0 1.1 1.7e-09 37.5 0.8 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR71922.1 - 1.4e-06 28.4 0.2 2.6e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 EMR71922.1 - 0.00019 21.7 0.2 0.00038 20.8 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.5 EMR71922.1 - 0.00048 19.3 0.0 0.097 11.7 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EMR71922.1 - 0.007 15.8 0.1 0.011 15.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EMR71922.1 - 0.018 14.2 0.3 0.03 13.5 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family Ribosomal_L15e PF00827.12 EMR71923.1 - 1.4e-91 305.1 11.7 1.6e-91 305.0 8.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 DJ-1_PfpI PF01965.19 EMR71924.1 - 5.8e-26 90.7 0.0 8.8e-26 90.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EMR71924.1 - 1.5e-14 53.1 0.0 3.1e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 EMR71924.1 - 0.031 13.5 0.0 0.11 11.7 0.0 1.9 1 1 0 1 1 1 0 Putative amidotransferase Carn_acyltransf PF00755.15 EMR71925.1 - 4.1e-164 546.9 0.0 1.1e-147 492.7 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase AcetylCoA_hyd_C PF13336.1 EMR71925.1 - 0.02 14.5 0.1 0.067 12.8 0.0 1.8 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain Nramp PF01566.13 EMR71926.1 - 1.5e-91 306.8 15.6 1.5e-91 306.8 10.8 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein DUF500 PF04366.7 EMR71927.1 - 8.3e-27 93.1 0.1 1.4e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EMR71927.1 - 6.9e-14 50.9 0.0 1.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMR71927.1 - 1.3e-13 50.1 0.2 8.1e-13 47.6 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EMR71927.1 - 1.5e-13 50.0 0.0 3.1e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain FGGY_C PF02782.11 EMR71928.1 - 2.3e-72 242.8 2.9 2.3e-72 242.8 2.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EMR71928.1 - 3.8e-54 183.5 0.0 5.5e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain RNA_pol_3_Rpc31 PF11705.3 EMR71929.1 - 0.08 12.8 24.1 0.49 10.2 3.4 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Sigma70_ner PF04546.8 EMR71929.1 - 1.5 8.4 22.9 0.18 11.3 5.8 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EMR71929.1 - 1.8 8.0 24.0 0.53 9.7 6.6 2.2 2 0 0 2 2 2 0 Nucleoplasmin FYDLN_acid PF09538.5 EMR71929.1 - 2.9 8.5 19.6 3.2 8.3 5.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Nop14 PF04147.7 EMR71929.1 - 3 5.6 23.3 4.6 5.0 16.2 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EMR71929.1 - 3.6 5.9 21.1 2.5 6.4 3.7 2.0 2 0 0 2 2 2 0 Daxx Family RXT2_N PF08595.6 EMR71929.1 - 5.5 6.7 17.3 1.1 9.1 4.8 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Vfa1 PF08432.5 EMR71929.1 - 9.7 6.1 17.6 2.4 8.1 3.9 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 ArfGap PF01412.13 EMR71930.1 - 7.6e-41 138.5 0.5 1.2e-40 137.9 0.4 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Lactamase_B_2 PF12706.2 EMR71931.1 - 6.1e-38 130.3 0.1 8.6e-38 129.8 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EMR71931.1 - 5.5e-09 35.9 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EMR71931.1 - 0.074 12.6 7.5 0.046 13.3 1.7 2.9 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily RXT2_N PF08595.6 EMR71933.1 - 3.2e-24 85.4 1.3 3.2e-24 85.4 0.9 2.4 2 1 0 2 2 2 1 RXT2-like, N-terminal DUF2435 PF10363.4 EMR71934.1 - 1.8e-17 62.9 0.9 6.4e-17 61.2 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EMR71934.1 - 5e-08 32.2 0.0 1.6e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) V-ATPase_H_N PF03224.9 EMR71934.1 - 0.0015 17.7 1.7 1.7 7.6 0.0 3.1 2 1 0 2 2 2 2 V-ATPase subunit H HEAT_EZ PF13513.1 EMR71934.1 - 0.09 13.2 5.9 7.5 7.1 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat SLAC1 PF03595.12 EMR71935.1 - 4e-49 167.0 29.4 3.9e-48 163.8 20.3 1.9 1 1 0 1 1 1 1 Voltage-dependent anion channel Nop53 PF07767.6 EMR71936.1 - 0.012 14.6 0.2 0.014 14.3 0.2 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Synaptobrevin PF00957.16 EMR71937.1 - 0.0054 16.3 0.5 0.025 14.1 0.2 1.9 1 1 1 2 2 2 1 Synaptobrevin SNARE PF05739.14 EMR71937.1 - 0.083 12.5 0.1 0.13 11.9 0.0 1.3 1 1 0 1 1 1 0 SNARE domain PEMT PF04191.8 EMR71938.1 - 5.1e-32 110.1 2.8 5.1e-32 110.1 1.9 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase Gryzun PF07919.7 EMR71939.1 - 1.7e-42 145.4 0.2 6.2e-21 74.3 0.0 2.0 1 1 1 2 2 2 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.2 EMR71939.1 - 0.0021 17.8 0.0 0.026 14.3 0.0 2.2 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking DUF2457 PF10446.4 EMR71939.1 - 3.8 6.1 17.1 6.3 5.4 11.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GMC_oxred_C PF05199.8 EMR71940.1 - 2.1e-27 96.1 0.0 3.6e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR71940.1 - 3.4e-27 95.3 0.0 2e-24 86.2 0.0 2.9 1 1 0 2 2 2 2 GMC oxidoreductase DAO PF01266.19 EMR71940.1 - 0.00015 20.7 0.0 0.0003 19.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR71940.1 - 0.00058 19.7 0.0 0.0045 16.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR71940.1 - 0.002 17.0 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EMR71940.1 - 0.0022 16.9 0.1 0.0057 15.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EMR71940.1 - 0.0071 16.3 0.2 0.016 15.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR71940.1 - 0.086 12.8 0.1 2 8.4 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EMR71940.1 - 0.22 11.3 0.1 0.44 10.3 0.1 1.4 1 0 0 1 1 1 0 ThiF family VSP PF03302.8 EMR71941.1 - 0.00012 20.8 0.6 0.0002 20.1 0.4 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.5 EMR71941.1 - 0.0014 17.9 6.0 0.0027 16.9 4.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 EMR71941.1 - 0.012 15.1 0.4 0.012 15.1 0.3 2.2 3 0 0 3 3 3 0 Podoplanin Adeno_E3_CR2 PF02439.10 EMR71941.1 - 0.023 14.2 0.2 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Herpes_gE PF02480.11 EMR71941.1 - 0.031 12.5 0.0 0.059 11.6 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DAP10 PF07213.6 EMR71941.1 - 0.036 13.8 0.7 0.085 12.6 0.5 1.6 1 0 0 1 1 1 0 DAP10 membrane protein SPRY PF00622.23 EMR71942.1 - 5.9e-08 32.8 0.1 2.3e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 SPRY domain Peptidase_S8 PF00082.17 EMR71944.1 - 7.9e-51 172.8 7.3 1.5e-50 171.9 5.1 1.4 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EMR71944.1 - 9.2e-09 35.6 0.0 3.2e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EMR71944.1 - 5.8e-06 25.9 1.4 9.5e-06 25.2 0.1 2.0 2 0 0 2 2 2 1 PA domain Sterol_MT_C PF08498.5 EMR71945.1 - 3.9e-25 87.5 0.0 6.9e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EMR71945.1 - 6.5e-21 74.6 0.0 1.7e-20 73.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR71945.1 - 3.3e-17 62.4 0.0 5e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR71945.1 - 2.3e-15 56.6 0.0 3.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR71945.1 - 6.7e-13 48.8 0.0 1.5e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EMR71945.1 - 2.5e-12 46.4 0.0 3.5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EMR71945.1 - 2.7e-11 43.0 0.0 7.2e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EMR71945.1 - 3.4e-11 43.7 0.0 1e-10 42.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR71945.1 - 8e-11 42.2 0.0 2e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR71945.1 - 2.9e-09 36.9 0.0 1.1e-08 35.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EMR71945.1 - 0.00083 18.9 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EMR71945.1 - 0.0029 16.9 0.0 0.0059 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EMR71945.1 - 0.0079 15.7 0.0 0.021 14.3 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EMR71945.1 - 0.0091 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.11 EMR71945.1 - 0.015 13.6 0.0 0.023 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.8 EMR71945.1 - 0.018 14.1 0.0 0.049 12.7 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 EMR71945.1 - 0.052 12.7 0.0 0.097 11.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_32 PF13679.1 EMR71945.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EMR71945.1 - 0.13 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Abhydrolase_4 PF08386.5 EMR71946.1 - 3.3e-17 62.2 0.0 4.8e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EMR71946.1 - 0.018 14.5 0.0 0.18 11.3 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR71946.1 - 0.072 12.8 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.20 EMR71947.1 - 1.7e-07 31.2 0.1 3.3e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR71947.1 - 0.00077 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Cyto_heme_lyase PF01265.12 EMR71948.1 - 1.2e-66 224.9 0.0 1.5e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ABC1 PF03109.11 EMR71949.1 - 1.4e-25 89.5 0.0 2.9e-15 56.2 0.0 2.5 1 1 1 2 2 2 2 ABC1 family APH PF01636.18 EMR71949.1 - 0.00017 21.3 1.7 0.00074 19.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family K_oxygenase PF13434.1 EMR71950.1 - 2.7e-107 358.6 0.0 3.2e-107 358.3 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EMR71950.1 - 7.4e-11 42.4 0.0 2e-10 41.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR71950.1 - 1.9e-08 34.2 0.0 4.9e-07 29.6 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EMR71950.1 - 7.2e-05 22.7 0.0 0.00043 20.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 EMR71951.1 - 5.8e-67 226.2 0.0 8.5e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 4HBT_2 PF13279.1 EMR71953.1 - 4.7e-08 33.5 0.0 4.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Peroxidase_2 PF01328.12 EMR71954.1 - 7.7e-14 51.0 0.1 3.6e-13 48.8 0.1 1.7 1 1 0 1 1 1 1 Peroxidase, family 2 Condensation PF00668.15 EMR71955.1 - 3e-27 95.2 0.0 1.5e-26 92.9 0.0 1.9 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EMR71955.1 - 3.3e-10 40.0 0.3 1.2e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site WES_acyltransf PF03007.11 EMR71955.1 - 0.00099 18.7 0.0 0.0024 17.4 0.0 1.6 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Choline_kinase PF01633.15 EMR71956.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase PTR2 PF00854.16 EMR71957.1 - 1.4e-28 99.7 16.4 2.4e-28 98.9 6.8 3.1 1 1 1 2 2 2 1 POT family DUF1469 PF07332.6 EMR71957.1 - 0.0013 18.4 0.6 0.0013 18.4 0.4 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF1469) INSIG PF07281.7 EMR71957.1 - 0.013 14.8 1.1 0.19 11.0 0.1 2.6 1 1 1 2 2 2 0 Insulin-induced protein (INSIG) CcmH PF03918.9 EMR71957.1 - 0.014 14.3 1.2 6.4 5.7 0.0 3.1 2 1 1 3 3 3 0 Cytochrome C biogenesis protein DUF4311 PF14188.1 EMR71957.1 - 0.041 13.3 5.1 0.041 13.3 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4311) Herpes_US9 PF06072.6 EMR71957.1 - 0.085 12.6 0.6 3.1 7.6 0.1 2.8 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Lipoxygenase PF00305.14 EMR71959.1 - 9.4e-33 113.1 0.0 1.2e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Lipoxygenase MFS_1 PF07690.11 EMR71960.1 - 1e-30 106.7 39.2 1.3e-30 106.3 27.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ATP_synt_I PF03899.10 EMR71960.1 - 0.011 15.8 5.5 0.011 15.8 3.8 3.2 1 1 1 2 2 2 0 ATP synthase I chain HET PF06985.6 EMR71962.1 - 4.8e-22 78.6 0.4 7.6e-22 77.9 0.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FTP PF07504.8 EMR71963.1 - 5.9e-14 51.2 1.3 8.7e-14 50.7 0.9 1.3 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif p450 PF00067.17 EMR71964.1 - 9.1e-31 106.8 0.0 1.6e-21 76.4 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 MIF4G_like PF09088.6 EMR71964.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 MIF4G like DUF2673 PF10880.3 EMR71964.1 - 0.086 12.8 0.1 1.1 9.3 0.0 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF2673) Fungal_trans PF04082.13 EMR71965.1 - 2.9e-05 23.1 0.1 5.7e-05 22.1 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain PAT1 PF09770.4 EMR71965.1 - 0.57 8.3 12.5 0.79 7.8 8.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SRR1 PF07985.7 EMR71966.1 - 0.0017 18.2 0.5 0.11 12.3 0.3 2.3 1 1 0 1 1 1 1 SRR1 DUF1018 PF06252.7 EMR71966.1 - 0.024 15.1 0.0 3 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) Ricin_B_lectin PF00652.17 EMR71967.1 - 4.2e-08 33.2 0.0 0.0056 16.7 0.0 3.2 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain Cript PF10235.4 EMR71968.1 - 0.16 12.3 0.3 1.3 9.4 0.1 2.2 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Pyr_redox_3 PF13738.1 EMR71969.1 - 2e-20 73.7 0.0 3.1e-19 69.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR71969.1 - 8.7e-07 28.8 0.3 3.3e-06 27.0 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR71969.1 - 0.0007 19.5 2.1 0.59 9.9 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR71969.1 - 0.0032 17.2 1.4 0.6 9.8 0.1 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding FMO-like PF00743.14 EMR71969.1 - 0.0071 14.6 0.0 0.094 10.8 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.14 EMR71969.1 - 0.027 13.6 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.1 EMR71969.1 - 0.059 12.2 0.0 3.9 6.3 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EMR71969.1 - 0.14 12.2 0.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Cyclase PF04199.8 EMR71970.1 - 6.1e-17 61.8 0.4 8.9e-17 61.3 0.3 1.2 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.7 EMR71970.1 - 0.088 12.2 0.1 0.32 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Polysacc_deac_1 PF01522.16 EMR71971.1 - 8.1e-07 28.7 0.0 1.5e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EMR71971.1 - 0.0043 16.0 0.0 0.005 15.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 WW PF00397.21 EMR71972.1 - 0.0001 22.0 3.6 0.00039 20.2 2.3 2.1 2 0 0 2 2 2 1 WW domain Na_trans_assoc PF06512.8 EMR71972.1 - 0.065 13.1 0.5 0.089 12.7 0.4 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2853 PF11015.3 EMR71972.1 - 0.12 12.8 0.6 0.22 12.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) DUF4404 PF14357.1 EMR71972.1 - 0.91 9.9 3.6 1.8 9.0 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) p450 PF00067.17 EMR71974.1 - 2.8e-42 144.8 0.0 1e-34 119.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 adh_short PF00106.20 EMR71975.1 - 2.1e-22 79.7 0.9 2.7e-22 79.4 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR71975.1 - 5e-11 42.5 0.8 7.1e-11 42.1 0.5 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR71975.1 - 1.5e-07 31.4 0.0 2.2e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EMR71975.1 - 0.00042 20.0 0.4 0.0023 17.6 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EMR71975.1 - 0.0037 16.3 0.0 0.0075 15.3 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DDE_Tnp_1_3 PF13612.1 EMR71975.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Peptidase_C14 PF00656.17 EMR71976.1 - 4.3e-69 232.9 0.0 5.8e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain HCO3_cotransp PF00955.16 EMR71977.1 - 4e-71 240.2 10.2 6.1e-42 143.9 2.3 2.1 1 1 1 2 2 2 2 HCO3- transporter family Med8 PF10232.4 EMR71978.1 - 3.8e-12 46.2 10.0 2.3e-11 43.6 7.0 2.0 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 RP-C_C PF11800.3 EMR71978.1 - 0.33 10.6 3.8 0.49 10.0 2.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Dicty_REP PF05086.7 EMR71978.1 - 0.35 8.5 2.6 0.4 8.3 1.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HATPase_c PF02518.21 EMR71980.1 - 3.9e-31 107.0 0.1 7.1e-31 106.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EMR71980.1 - 2.1e-22 79.2 0.1 4.3e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EMR71980.1 - 6.3e-22 77.3 1.3 8.7e-22 76.8 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EMR71980.1 - 0.003 17.2 0.0 0.0075 15.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rif1_N PF12231.3 EMR71981.1 - 7.1e-141 469.4 0.9 8.8e-141 469.1 0.6 1.1 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal 2OG-FeII_Oxy PF03171.15 EMR71982.1 - 1.1e-13 51.3 0.0 2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EMR71982.1 - 1.5e-13 51.3 0.0 2.6e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF4073 PF13285.1 EMR71982.1 - 0.0039 16.6 0.0 0.0086 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4073) LigD_N PF13298.1 EMR71983.1 - 7.5e-08 32.4 0.0 0.00022 21.2 0.1 3.1 1 1 1 2 2 2 2 DNA polymerase Ligase (LigD) MSP1_C PF07462.6 EMR71983.1 - 0.088 11.1 7.6 0.067 11.5 2.3 2.1 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus DUF2146 PF10220.4 EMR71983.1 - 6.9 4.5 10.7 0.066 11.2 0.1 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2146) Chromo PF00385.19 EMR71984.1 - 1.8e-17 62.7 0.6 3.9e-17 61.6 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AT_hook PF02178.14 EMR71984.1 - 0.044 13.4 1.1 0.044 13.4 0.8 2.9 3 0 0 3 3 3 0 AT hook motif PQ-loop PF04193.9 EMR71985.1 - 8.6e-24 82.8 6.8 3.7e-15 55.2 0.6 2.8 3 0 0 3 3 3 2 PQ loop repeat Condensation PF00668.15 EMR71986.1 - 2.9e-28 98.6 0.0 4e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Transferase PF02458.10 EMR71986.1 - 0.0098 14.3 0.0 0.015 13.7 0.0 1.2 1 0 0 1 1 1 1 Transferase family Aldose_epim PF01263.15 EMR71987.1 - 6.3e-39 133.8 0.0 7.6e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DAHP_synth_2 PF01474.11 EMR71989.1 - 9.4e-182 604.2 0.0 1.1e-181 604.0 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Sulfatase PF00884.18 EMR71990.1 - 1e-48 166.1 0.1 1.4e-48 165.7 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EMR71990.1 - 1.7e-19 69.3 0.6 4.1e-19 68.1 0.3 1.8 1 1 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EMR71990.1 - 1.2e-07 31.4 0.1 0.00031 20.1 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EMR71990.1 - 0.00069 19.9 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 EMR71990.1 - 0.0016 16.9 0.0 0.0024 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Dynein_light PF01221.13 EMR71991.1 - 2.7e-41 139.4 0.9 3.1e-41 139.2 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Tet_JBP PF12851.2 EMR71995.1 - 0.00018 20.8 0.0 0.00058 19.1 0.0 1.8 2 0 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily MLIP PF15274.1 EMR71997.1 - 0.043 13.3 1.7 0.066 12.6 1.2 1.2 1 0 0 1 1 1 0 Muscular LMNA-interacting protein RNase_P_p30 PF01876.11 EMR71998.1 - 1.7e-40 137.6 0.0 2.8e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 CDC45 PF02724.9 EMR71998.1 - 0.0064 14.5 0.9 0.0077 14.3 0.7 1.1 1 0 0 1 1 1 1 CDC45-like protein Rtf2 PF04641.7 EMR71998.1 - 0.25 10.5 8.6 0.41 9.8 5.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Paf1 PF03985.8 EMR71998.1 - 2.4 6.8 8.1 0.03 13.0 0.5 1.4 2 0 0 2 2 2 0 Paf1 Pup PF05639.6 EMR71999.1 - 0.0014 19.0 1.1 0.0014 19.0 0.7 3.3 3 0 0 3 3 3 1 Pup-like protein RRM_1 PF00076.17 EMR72001.1 - 2.4e-74 244.9 0.2 2.8e-21 74.9 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR72001.1 - 7.1e-66 218.1 0.3 1.3e-18 66.7 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR72001.1 - 5.5e-32 109.3 0.0 1.4e-09 37.6 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMR72001.1 - 5.7e-09 35.6 0.1 0.009 15.7 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EMR72001.1 - 1.2e-08 34.6 0.5 0.39 10.4 0.0 5.8 5 1 0 5 5 5 2 Limkain b1 RRM_2 PF04059.7 EMR72001.1 - 1.4e-05 25.0 0.0 0.16 11.9 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif 2 RRM_3 PF08777.6 EMR72001.1 - 0.00025 20.8 0.0 1.6 8.6 0.0 4.6 4 0 0 4 4 4 1 RNA binding motif Ric8 PF10165.4 EMR72002.1 - 3.6e-62 210.6 0.1 1.4e-50 172.4 0.0 2.3 1 1 1 2 2 2 2 Guanine nucleotide exchange factor synembryn TAFII55_N PF04658.8 EMR72003.1 - 4.6e-40 136.7 0.0 8.4e-40 135.9 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region CCDC32 PF14989.1 EMR72003.1 - 0.0056 16.5 2.7 0.014 15.2 1.9 1.6 1 0 0 1 1 1 1 Coiled-coil domain containing 32 Cellulase PF00150.13 EMR72004.1 - 5e-40 137.4 0.2 7.9e-40 136.8 0.2 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ank_2 PF12796.2 EMR72005.1 - 2.3e-22 79.1 2.3 2.6e-17 62.9 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EMR72005.1 - 1.1e-14 53.3 0.1 2.6e-08 33.2 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EMR72005.1 - 3.1e-14 52.6 0.9 1.2e-07 31.6 0.2 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR72005.1 - 9.8e-10 38.6 0.2 9.9e-07 29.1 0.0 2.9 2 1 1 3 3 2 2 Ankyrin repeats (many copies) NACHT PF05729.7 EMR72005.1 - 2.4e-09 37.0 0.0 7.2e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.1 EMR72005.1 - 1.7e-08 33.9 0.1 4.5e-05 23.2 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat AAA_22 PF13401.1 EMR72005.1 - 0.00011 22.3 0.1 0.00094 19.3 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EMR72005.1 - 0.0012 18.8 0.3 0.005 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 EMR72005.1 - 0.0038 16.4 0.0 0.0075 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EMR72005.1 - 0.0083 15.7 0.1 0.076 12.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMR72005.1 - 0.0089 16.3 0.1 0.096 13.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EMR72005.1 - 0.0096 15.3 0.0 0.18 11.1 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.1 EMR72005.1 - 0.017 14.8 0.0 0.064 13.0 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EMR72005.1 - 0.025 14.7 0.0 0.085 13.0 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EMR72005.1 - 0.038 12.9 0.0 0.088 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 EMR72005.1 - 0.08 12.8 0.2 1.7 8.5 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EMR72005.1 - 0.12 13.2 0.4 1.8 9.4 0.0 3.0 2 1 0 2 2 2 0 AAA domain Enkurin PF13864.1 EMR72005.1 - 0.79 9.9 5.1 2 8.6 2.3 2.6 2 0 0 2 2 2 0 Calmodulin-binding bZIP_1 PF00170.16 EMR72006.1 - 0.0006 19.7 9.3 0.0006 19.7 6.4 1.6 2 0 0 2 2 2 1 bZIP transcription factor PAP1 PF08601.5 EMR72006.1 - 0.0013 18.5 0.1 0.007 16.0 0.0 1.9 2 0 0 2 2 2 1 Transcription factor PAP1 TSC22 PF01166.13 EMR72006.1 - 0.12 12.3 2.5 0.36 10.8 1.7 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF904 PF06005.7 EMR72006.1 - 4.5 7.6 11.9 0.2 11.9 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 EMR72006.1 - 4.6 7.1 13.6 56 3.6 9.4 2.2 1 1 0 1 1 1 0 Basic region leucine zipper NYD-SP28_assoc PF14775.1 EMR72006.1 - 7.3 6.3 9.2 0.71 9.6 2.2 2.3 1 1 1 2 2 2 0 Sperm tail C-terminal domain 7tm_2 PF00002.19 EMR72007.1 - 6.5e-05 22.1 9.6 0.00013 21.1 6.7 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EMR72007.1 - 0.00015 20.8 2.8 0.00015 20.8 2.0 1.5 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor SNF2_N PF00176.18 EMR72008.1 - 4.2e-26 91.4 0.5 6.2e-26 90.8 0.4 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EMR72008.1 - 3.6e-12 45.9 0.0 6.5e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromo_TP PF07524.8 EMR72009.1 - 1.4e-07 31.1 0.0 2.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated ProQ PF04352.8 EMR72009.1 - 0.26 10.9 1.5 1.2 8.7 0.1 2.3 2 1 0 2 2 2 0 ProQ/FINO family Glyco_hydro_15 PF00723.16 EMR72010.1 - 4.3e-52 177.1 0.0 7.2e-50 169.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 F-box PF00646.28 EMR72011.1 - 0.0061 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMR72011.1 - 0.039 13.6 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 F-box-like Transket_pyr PF02779.19 EMR72012.1 - 9.5e-65 217.4 0.0 1.8e-64 216.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EMR72012.1 - 1e-55 188.6 0.0 1.4e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Mito_carr PF00153.22 EMR72013.1 - 9.2e-45 150.2 10.2 7.4e-17 60.8 0.2 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein SR-25 PF10500.4 EMR72013.1 - 5.7 6.3 8.3 9.7 5.5 5.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.27 EMR72014.1 - 2.9e-46 153.7 21.4 5.7e-12 45.0 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EMR72014.1 - 0.59 8.8 2.5 4.8 5.8 0.3 2.1 2 0 0 2 2 2 0 Coatomer WD associated region ATP_bind_3 PF01171.15 EMR72016.1 - 1.2e-33 116.1 0.0 2.1e-21 76.2 0.0 2.3 1 1 1 2 2 2 2 PP-loop family DDHD PF02862.12 EMR72017.1 - 1.2e-35 123.4 0.0 1.3e-34 119.9 0.0 2.2 1 1 0 1 1 1 1 DDHD domain Abhydrolase_6 PF12697.2 EMR72017.1 - 0.00096 19.0 0.2 0.0019 18.1 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR72017.1 - 0.0068 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EMR72017.1 - 0.044 13.1 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 EMR72017.1 - 0.078 12.2 0.0 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) UPF0154 PF03672.8 EMR72017.1 - 0.09 12.4 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) HSP20 PF00011.16 EMR72017.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Hsp20/alpha crystallin family DUF4098 PF13345.1 EMR72019.1 - 0.0086 16.0 6.7 2 8.4 0.5 4.7 4 2 0 4 4 4 3 Domain of unknown function (DUF4098) DUF3337 PF11816.3 EMR72020.1 - 2.8e-42 145.3 7.4 2.5e-31 109.3 3.9 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EMR72020.1 - 6.7e-26 89.2 19.6 7.5e-07 28.8 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EMR72020.1 - 0.0066 14.6 1.2 0.03 12.4 0.0 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Adaptin_binding PF10199.4 EMR72020.1 - 0.017 15.3 1.7 0.017 15.3 1.2 2.3 3 0 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 GBP_C PF02841.9 EMR72020.1 - 0.069 12.3 8.1 0.11 11.6 5.6 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain WD40 PF00400.27 EMR72021.1 - 0.0002 21.1 0.9 0.09 12.6 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Hira PF07569.6 EMR72021.1 - 0.071 12.3 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 TUP1-like enhancer of split Apc4_WD40 PF12894.2 EMR72021.1 - 0.12 11.8 0.0 6.7 6.2 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cupin_8 PF13621.1 EMR72022.1 - 4e-35 121.5 0.0 4.6e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EMR72022.1 - 1.3e-05 24.5 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein DAO PF01266.19 EMR72023.1 - 2.1e-50 171.6 0.0 3.1e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR72023.1 - 2.5e-11 43.0 0.3 7.3e-11 41.5 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EMR72023.1 - 1.9e-07 30.5 3.1 3.1e-06 26.5 2.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EMR72023.1 - 0.00013 21.1 0.3 0.0092 15.0 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EMR72023.1 - 0.00014 21.7 0.1 0.0017 18.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMR72023.1 - 0.0003 19.9 0.1 0.036 13.1 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EMR72023.1 - 0.0019 18.2 0.1 0.0073 16.3 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EMR72023.1 - 0.0041 16.7 0.3 0.0078 15.8 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EMR72023.1 - 0.013 14.4 0.0 0.55 9.0 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EMR72023.1 - 0.024 14.6 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EMR72023.1 - 0.029 12.8 0.3 0.047 12.1 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EMR72023.1 - 0.039 14.3 0.8 0.13 12.6 0.5 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 EMR72023.1 - 0.079 11.2 0.1 0.2 9.9 0.0 1.6 2 0 0 2 2 2 0 GDP dissociation inhibitor GIDA PF01134.17 EMR72023.1 - 0.11 11.3 0.1 0.56 9.0 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 EMR72023.1 - 0.12 12.4 0.0 0.99 9.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DSPc PF00782.15 EMR72024.1 - 1.6e-26 92.4 0.0 2.9e-21 75.4 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EMR72024.1 - 1.3e-05 24.6 0.0 0.0001 21.7 0.0 2.2 2 1 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EMR72024.1 - 0.12 12.3 0.0 0.6 10.1 0.1 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate BSD PF03909.12 EMR72025.1 - 1.4e-22 79.1 0.6 8.9e-12 44.5 0.0 3.2 2 1 0 2 2 2 2 BSD domain Spermine_synth PF01564.12 EMR72025.1 - 0.031 13.2 0.1 0.058 12.3 0.0 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase MHYT PF03707.11 EMR72026.1 - 7.1e-10 38.8 15.7 5.3e-05 23.2 0.1 4.0 2 1 0 3 3 3 2 Bacterial signalling protein N terminal repeat Neurensin PF14927.1 EMR72026.1 - 0.027 13.8 0.3 2.6 7.4 0.1 2.6 2 0 0 2 2 2 0 Neurensin p450 PF00067.17 EMR72028.1 - 1.4e-59 201.8 0.0 1.9e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.1 EMR72029.1 - 0.0032 17.5 0.0 0.0033 17.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR72029.1 - 0.031 14.2 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR72029.1 - 0.065 13.1 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1290 PF06947.7 EMR72030.1 - 0.36 10.7 2.7 2.6 7.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1290) Glyco_hydro_3 PF00933.16 EMR72031.1 - 1.5e-79 267.1 0.0 2.2e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EMR72031.1 - 4.3e-64 216.1 0.0 1.8e-63 214.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EMR72031.1 - 1.2e-13 50.7 0.0 3e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EMR72031.1 - 1e-11 44.6 0.0 2.2e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 PA14 domain PIG-L PF02585.12 EMR72031.1 - 0.045 14.2 0.1 2.5 8.6 0.0 2.6 2 0 0 2 2 2 0 GlcNAc-PI de-N-acetylase 4HBT_3 PF13622.1 EMR72032.1 - 1.6e-29 103.4 1.0 2e-29 103.1 0.7 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMR72032.1 - 2.3e-09 36.9 0.0 5e-06 26.1 0.0 2.8 2 1 1 3 3 3 2 Acyl-CoA thioesterase 4HBT PF03061.17 EMR72032.1 - 0.031 14.3 0.1 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Thioesterase superfamily p450 PF00067.17 EMR72033.1 - 2.8e-53 181.1 0.0 1.8e-31 109.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Beta_elim_lyase PF01212.16 EMR72035.1 - 1.9e-67 227.4 0.0 3.1e-66 223.4 0.0 2.2 2 0 0 2 2 2 1 Beta-eliminating lyase Trp_DMAT PF11991.3 EMR72035.1 - 1.9e-17 63.5 0.0 3.2e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Esterase_phd PF10503.4 EMR72035.1 - 0.036 13.2 0.1 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF3632 PF12311.3 EMR72036.1 - 3.3e-20 72.6 0.0 4.3e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) 4HBT_3 PF13622.1 EMR72037.1 - 4.2e-14 52.8 0.4 4.6e-14 52.7 0.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMR72037.1 - 6.7e-09 35.4 0.0 8.7e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA thioesterase Nol1_Nop2_Fmu PF01189.12 EMR72038.1 - 8.2e-17 61.4 0.0 4e-16 59.2 0.0 2.0 1 1 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EMR72038.1 - 0.0059 16.6 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EMR72038.1 - 0.039 13.9 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain APG5 PF04106.7 EMR72041.1 - 1e-43 149.1 0.0 1.6e-43 148.4 0.0 1.4 1 1 0 1 1 1 1 Autophagy protein Apg5 PNK3P PF08645.6 EMR72042.1 - 1.8e-31 108.7 0.0 2.2e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Hydrolase_like PF13242.1 EMR72042.1 - 0.089 12.5 0.1 0.39 10.4 0.1 2.1 1 1 0 1 1 1 0 HAD-hyrolase-like Pro_CA PF00484.14 EMR72043.1 - 6.8e-49 165.7 0.1 8.7e-49 165.4 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Saf-Nte_pilin PF09460.5 EMR72043.1 - 0.046 13.4 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Saf-pilin pilus formation protein Thiolase_N PF00108.18 EMR72044.1 - 2.3e-70 236.5 1.7 3.3e-70 236.1 1.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EMR72044.1 - 1.8e-40 137.1 0.1 5.6e-40 135.5 0.1 1.9 1 0 0 1 1 1 1 Thiolase, C-terminal domain DUF433 PF04255.9 EMR72044.1 - 0.056 12.8 0.0 0.59 9.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Glyco_hydro_cc PF11790.3 EMR72045.1 - 2.2e-67 226.9 0.1 2.6e-67 226.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fip1 PF05182.8 EMR72045.1 - 0.029 13.6 2.9 0.066 12.4 2.0 1.5 1 0 0 1 1 1 0 Fip1 motif Glyco_transf_90 PF05686.7 EMR72046.1 - 1.4e-23 83.2 1.0 2.2e-23 82.6 0.7 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 p450 PF00067.17 EMR72047.1 - 7e-45 153.4 0.0 9.6e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EMR72049.1 - 2.9e-13 49.3 0.1 5e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.18 EMR72050.1 - 8.6e-75 251.6 35.0 1.4e-41 142.7 11.6 3.1 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMR72050.1 - 2.6e-64 215.6 0.0 6e-31 107.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMR72050.1 - 6.9e-14 52.4 0.0 4.9e-06 26.7 0.1 4.4 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EMR72050.1 - 2e-13 50.0 3.6 3.4e-06 26.4 0.0 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EMR72050.1 - 2.4e-08 33.3 0.1 0.00088 18.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EMR72050.1 - 4.1e-08 32.2 0.2 0.0087 14.6 0.0 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EMR72050.1 - 3e-07 30.5 0.4 0.0045 16.9 0.0 2.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EMR72050.1 - 3.9e-07 29.6 0.0 0.035 13.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EMR72050.1 - 7.7e-07 28.4 0.0 0.044 12.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EMR72050.1 - 1.1e-06 28.7 0.1 0.066 13.3 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EMR72050.1 - 5.1e-06 27.2 0.0 0.14 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EMR72050.1 - 0.00011 21.7 0.1 2.1 7.8 0.0 3.9 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.1 EMR72050.1 - 0.00017 21.4 1.9 0.5 10.3 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EMR72050.1 - 0.00024 21.0 0.0 1.4 8.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EMR72050.1 - 0.00033 19.7 0.0 0.51 9.4 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.1 EMR72050.1 - 0.00044 20.1 0.0 0.89 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EMR72050.1 - 0.0009 18.9 0.0 2.6 7.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EMR72050.1 - 0.0019 18.1 0.1 0.85 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EMR72050.1 - 0.0022 18.2 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EMR72050.1 - 0.0032 17.6 0.1 7 6.8 0.0 3.7 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EMR72050.1 - 0.0073 16.6 0.0 3.8 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EMR72050.1 - 0.0097 15.6 0.0 4.2 7.0 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EMR72050.1 - 0.023 14.1 0.0 3.2 7.1 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EMR72050.1 - 0.034 13.5 0.9 13 5.1 0.1 3.3 3 0 0 3 3 3 0 AAA-like domain APS_kinase PF01583.15 EMR72050.1 - 0.034 13.8 0.0 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EMR72050.1 - 0.065 13.4 0.1 4 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.12 EMR72050.1 - 0.069 12.9 0.0 12 5.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EMR72050.1 - 0.1 12.5 0.0 23 4.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3987 PF13148.1 EMR72050.1 - 0.11 11.0 0.0 6.4 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) G-alpha PF00503.15 EMR72050.1 - 0.29 9.7 0.0 17 3.9 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_15 PF13175.1 EMR72050.1 - 0.31 10.0 0.0 9.5 5.1 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.22 EMR72051.1 - 2.5e-50 170.3 0.1 1e-26 93.8 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMR72051.1 - 6.3e-15 55.8 4.4 1.6e-05 25.0 0.1 3.8 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EMR72051.1 - 2.9e-12 46.3 0.0 0.0019 17.4 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EMR72051.1 - 1.1e-07 32.3 0.4 0.0037 17.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EMR72051.1 - 3.2e-07 29.7 0.9 0.012 15.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 EMR72051.1 - 2.4e-06 27.3 0.0 0.091 12.6 0.0 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 EMR72051.1 - 5.1e-06 26.4 0.0 0.029 14.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 EMR72051.1 - 5.2e-06 27.2 0.0 0.024 15.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMR72051.1 - 6.2e-06 25.4 0.0 0.027 13.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EMR72051.1 - 7.5e-06 25.5 0.9 0.29 10.5 0.1 4.1 4 0 0 4 4 4 2 AAA-like domain Miro PF08477.8 EMR72051.1 - 6.6e-05 23.3 0.0 0.064 13.7 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_15 PF13175.1 EMR72051.1 - 9.1e-05 21.6 0.0 1.3 8.0 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EMR72051.1 - 0.00022 21.3 0.0 0.91 9.6 0.0 3.2 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EMR72051.1 - 0.00024 20.9 0.1 0.11 12.3 0.0 3.4 2 1 1 3 3 3 1 Dynamin family AAA_33 PF13671.1 EMR72051.1 - 0.00091 19.1 0.0 0.71 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EMR72051.1 - 0.0021 17.5 0.0 2.2 7.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EMR72051.1 - 0.0021 17.7 0.1 0.24 11.0 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EMR72051.1 - 0.0021 16.8 0.3 0.62 8.7 0.0 2.5 2 0 0 2 2 2 1 ArgK protein RNA_helicase PF00910.17 EMR72051.1 - 0.0028 17.8 0.1 2.5 8.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.12 EMR72051.1 - 0.0032 17.3 1.1 0.42 10.3 0.0 3.2 3 0 0 3 3 2 1 Domain of unknown function DUF87 PduV-EutP PF10662.4 EMR72051.1 - 0.0052 16.2 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EMR72051.1 - 0.0075 16.5 0.1 0.62 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EMR72051.1 - 0.0081 15.8 0.4 4.7 6.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Chromo PF00385.19 EMR72051.1 - 0.0081 15.8 3.5 0.014 15.0 1.5 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_28 PF13521.1 EMR72051.1 - 0.018 15.0 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EMR72051.1 - 0.025 14.7 0.1 4.1 7.5 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EMR72051.1 - 0.027 14.0 0.4 6.6 6.2 0.0 3.1 4 0 0 4 4 2 0 AAA domain DUF815 PF05673.8 EMR72051.1 - 0.085 11.7 0.2 3.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_13 PF13166.1 EMR72051.1 - 0.098 11.1 1.9 7.2 4.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EMR72051.1 - 3.1 7.7 5.3 1.5 8.7 0.2 2.8 2 0 0 2 2 2 0 AAA ATPase domain RRM_6 PF14259.1 EMR72052.1 - 3.9e-08 33.1 0.0 5.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR72052.1 - 2.4e-07 30.2 0.0 3.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR72052.1 - 2.8e-06 27.0 0.0 4.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ubiquitin PF00240.18 EMR72052.1 - 0.013 14.8 0.3 0.61 9.5 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin family DbpA PF03880.10 EMR72052.1 - 0.12 12.0 0.1 0.97 9.1 0.1 2.1 1 1 0 1 1 1 0 DbpA RNA binding domain DDA1 PF10172.4 EMR72052.1 - 0.14 12.0 0.9 0.31 10.9 0.1 2.1 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase SpoIIIAH PF12685.2 EMR72052.1 - 1.4 8.4 4.1 1.4 8.4 0.1 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Mob_synth_C PF06463.8 EMR72053.1 - 1.9e-36 124.5 0.0 9.7e-36 122.2 0.0 2.0 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EMR72053.1 - 2.6e-21 76.5 0.0 4.4e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EMR72053.1 - 2.5e-05 24.2 0.0 0.0001 22.2 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EMR72053.1 - 3.1e-05 24.1 0.0 0.00014 21.9 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain DS PF01916.12 EMR72054.1 - 1e-145 484.4 0.0 1.2e-145 484.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase ABM PF03992.11 EMR72055.1 - 4.9e-07 29.7 3.8 0.0091 16.0 0.2 2.7 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.6 EMR72055.1 - 0.035 13.9 0.7 0.075 12.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) Imm6 PF14434.1 EMR72055.1 - 0.076 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Immunity protein Imm6 DUF3297 PF11730.3 EMR72055.1 - 0.077 12.6 0.3 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) DAG1 PF05454.6 EMR72056.1 - 1.6 7.7 10.6 0.31 10.1 4.8 1.6 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) PAN_4 PF14295.1 EMR72058.1 - 0.088 12.5 4.7 0.17 11.6 1.5 2.6 2 0 0 2 2 2 0 PAN domain Jnk-SapK_ap_N PF09744.4 EMR72059.1 - 0.1 12.5 9.7 0.24 11.3 6.7 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Synaptobrevin PF00957.16 EMR72059.1 - 0.26 10.9 2.1 0.43 10.2 0.1 2.3 2 1 1 3 3 3 0 Synaptobrevin DUF605 PF04652.11 EMR72059.1 - 0.78 9.0 10.4 1.1 8.6 7.2 1.2 1 0 0 1 1 1 0 Vta1 like DUF904 PF06005.7 EMR72059.1 - 1 9.7 8.1 49 4.3 0.0 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF904) APG6 PF04111.7 EMR72059.1 - 1.9 7.4 9.1 3.3 6.6 6.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_2 PF07716.10 EMR72060.1 - 0.023 14.5 0.2 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Lebercilin PF15619.1 EMR72060.1 - 0.039 13.3 0.8 0.042 13.2 0.5 1.0 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease VIT1 PF01988.14 EMR72060.1 - 0.12 11.8 0.2 0.12 11.8 0.1 1.0 1 0 0 1 1 1 0 VIT family OmdA PF13376.1 EMR72062.1 - 0.061 12.9 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF3484 PF11983.3 EMR72062.1 - 1.7 9.5 9.1 1.8 9.4 3.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) Methyltransf_2 PF00891.13 EMR72066.1 - 7.7e-30 103.8 0.0 1.2e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EMR72066.1 - 0.00032 20.4 0.0 0.00061 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HTH_AsnC-type PF13404.1 EMR72066.1 - 0.00034 20.0 0.0 0.00091 18.7 0.0 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.1 EMR72066.1 - 0.017 14.4 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Pro_isomerase PF00160.16 EMR72067.1 - 7.9e-41 139.8 0.0 1.8e-40 138.7 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Nbas_N PF15492.1 EMR72068.1 - 0.0059 15.7 0.1 0.55 9.2 0.0 3.0 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 EMR72068.1 - 0.065 12.4 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split HSF_DNA-bind PF00447.12 EMR72069.1 - 9.8e-29 99.5 0.5 2.4e-28 98.3 0.4 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding DUF536 PF04394.9 EMR72069.1 - 0.019 14.7 4.3 0.019 14.7 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF536 TMF_DNA_bd PF12329.3 EMR72069.1 - 0.02 14.6 6.5 0.54 10.0 0.9 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MRP-L28 PF09812.4 EMR72069.1 - 0.021 14.6 1.7 0.021 14.6 1.2 2.7 4 0 0 4 4 4 0 Mitochondrial ribosomal protein L28 DUF1548 PF07579.6 EMR72069.1 - 0.098 12.7 0.9 0.21 11.7 0.6 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) DivIC PF04977.10 EMR72069.1 - 0.43 10.0 7.2 3.3 7.2 0.1 2.6 2 0 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 EMR72069.1 - 0.58 10.4 10.8 5 7.4 1.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF904) LRR_4 PF12799.2 EMR72070.1 - 1.6e-33 113.7 31.3 1.2e-06 27.9 0.1 10.1 4 2 10 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EMR72070.1 - 9e-25 86.2 33.4 4.3e-07 29.5 1.4 7.8 6 2 2 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 EMR72070.1 - 3.8e-12 44.4 39.4 0.15 12.1 0.1 13.5 10 4 2 12 12 12 6 Leucine Rich Repeat LRR_6 PF13516.1 EMR72070.1 - 8.6e-08 31.4 36.5 0.3 11.2 0.3 11.5 10 3 1 11 11 11 4 Leucine Rich repeat LRR_7 PF13504.1 EMR72070.1 - 3.4e-07 29.3 48.2 1 9.8 0.5 14.3 15 2 1 16 16 16 4 Leucine rich repeat LRR_9 PF14580.1 EMR72070.1 - 0.00052 19.6 11.3 0.83 9.1 0.3 5.1 2 2 3 5 5 5 3 Leucine-rich repeat NosD PF05048.8 EMR72070.1 - 0.38 9.8 3.7 0.18 10.9 0.9 1.6 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) DEAD PF00270.24 EMR72071.1 - 3e-10 39.8 0.0 5.5e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EMR72071.1 - 3.3e-07 30.0 0.1 7.5e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EMR72071.1 - 0.082 12.7 0.3 0.45 10.3 0.0 2.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Gly_transf_sug PF04488.10 EMR72072.1 - 1e-12 48.3 0.0 2.6e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMR72072.1 - 0.0058 15.1 0.0 0.0093 14.4 0.0 1.3 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain RRM_1 PF00076.17 EMR72073.1 - 7.7e-44 147.1 0.5 8.3e-21 73.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR72073.1 - 1.1e-35 121.3 0.1 7.3e-19 67.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EMR72073.1 - 1.4e-29 102.1 0.1 3.4e-29 100.9 0.1 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EMR72073.1 - 2.2e-22 78.6 0.0 2.1e-09 37.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EMR72073.1 - 0.00044 20.0 0.2 0.016 15.0 0.0 3.0 3 1 0 3 3 3 1 RNA binding motif DUF3457 PF11939.3 EMR72074.1 - 9.7 5.6 9.2 89 2.5 6.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3457) Peptidase_M28 PF04389.12 EMR72075.1 - 6.5e-33 113.9 0.1 1.1e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EMR72075.1 - 1.6e-14 53.4 0.4 3.7e-14 52.2 0.3 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EMR72075.1 - 2.2e-05 24.0 0.0 5.4e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Hexapep PF00132.19 EMR72077.1 - 4.2e-09 35.4 15.6 0.00017 20.8 4.0 4.3 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EMR72077.1 - 0.00011 21.6 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EMR72077.1 - 0.0019 17.7 8.4 0.012 15.1 1.4 2.9 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 EMR72077.1 - 0.015 15.4 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain TPP_enzyme_N PF02776.13 EMR72077.1 - 0.059 12.8 0.6 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Fucokinase PF07959.7 EMR72077.1 - 0.66 8.4 1.8 1.7 7.1 0.7 1.8 1 1 1 2 2 2 0 L-fucokinase Septin PF00735.13 EMR72078.1 - 2e-32 112.3 0.0 3.9e-11 42.4 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 EMR72078.1 - 0.00053 19.5 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family KAP_NTPase PF07693.9 EMR72078.1 - 0.011 14.7 0.0 0.013 14.4 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain AAA_23 PF13476.1 EMR72078.1 - 0.013 15.8 4.2 0.045 14.0 2.9 1.9 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EMR72078.1 - 0.016 15.7 0.0 0.043 14.3 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 EMR72078.1 - 0.018 15.0 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.7 EMR72078.1 - 0.022 14.0 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_17 PF13207.1 EMR72078.1 - 0.036 14.8 0.1 0.036 14.8 0.1 2.3 2 2 0 2 2 2 0 AAA domain TFIIA PF03153.8 EMR72078.1 - 0.042 13.7 4.6 0.052 13.4 3.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_24 PF13479.1 EMR72078.1 - 0.05 13.1 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EMR72078.1 - 0.071 12.9 1.7 1.2 8.9 0.1 2.5 2 1 1 3 3 3 0 Dynamin family G-alpha PF00503.15 EMR72078.1 - 0.074 11.7 0.0 0.074 11.7 0.0 2.2 3 0 0 3 3 2 0 G-protein alpha subunit Nop14 PF04147.7 EMR72078.1 - 0.081 10.8 8.9 0.1 10.5 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family AAA_18 PF13238.1 EMR72078.1 - 0.092 13.0 1.6 0.2 11.9 0.0 2.4 2 2 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EMR72078.1 - 0.092 12.2 0.0 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EMR72078.1 - 0.11 12.3 0.0 0.35 10.7 0.0 1.9 3 0 0 3 3 2 0 AAA domain Daxx PF03344.10 EMR72078.1 - 3.2 6.1 11.7 4.5 5.6 8.1 1.1 1 0 0 1 1 1 0 Daxx Family Trypan_PARP PF05887.6 EMR72078.1 - 4.5 7.0 11.9 8.5 6.1 8.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) VID27 PF08553.5 EMR72078.1 - 5 5.2 7.3 6.9 4.7 5.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 EMR72078.1 - 9.1 4.1 10.7 13 3.7 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_B PF00136.16 EMR72079.1 - 1.4e-92 310.8 0.0 1.9e-92 310.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.1 EMR72079.1 - 8.8e-16 57.6 0.8 2.7e-15 56.1 0.1 2.2 2 1 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Ribosomal_L21e PF01157.13 EMR72080.1 - 7.3e-40 134.7 4.9 7.3e-40 134.7 3.4 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e COX6A PF02046.10 EMR72081.1 - 3.1e-47 159.2 1.4 3.6e-47 159.0 1.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa CIA30 PF08547.7 EMR72082.1 - 1.9e-41 141.5 0.0 2.8e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SR-25 PF10500.4 EMR72082.1 - 9.7 5.5 7.1 17 4.7 4.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ferric_reduct PF01794.14 EMR72083.1 - 5.4e-20 71.7 9.3 5.4e-20 71.7 6.5 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EMR72083.1 - 1.5e-19 70.4 0.0 9.3e-12 45.1 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EMR72083.1 - 1.5e-09 37.6 0.0 8.8e-09 35.1 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain DUF485 PF04341.7 EMR72083.1 - 5.7 6.7 11.3 16 5.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Apc5 PF12862.2 EMR72084.1 - 7.6e-34 115.4 5.0 7.6e-34 115.4 3.5 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 EMR72084.1 - 0.0077 16.1 16.7 0.056 13.3 0.1 6.2 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EMR72084.1 - 0.064 12.8 1.4 61 3.4 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMR72084.1 - 0.6 10.7 21.2 39 5.0 0.1 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat zf-GRF PF06839.7 EMR72085.1 - 1.9e-07 30.8 5.4 5.7e-07 29.3 3.8 1.8 1 1 0 1 1 1 1 GRF zinc finger ABC1 PF03109.11 EMR72086.1 - 2.3e-23 82.4 0.0 4.5e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EMR72086.1 - 1.7e-05 24.7 0.0 4.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family ANTH PF07651.11 EMR72087.1 - 7.3e-82 274.2 0.0 3.4e-81 272.0 0.0 2.2 1 0 0 1 1 1 1 ANTH domain I_LWEQ PF01608.12 EMR72087.1 - 3.9e-61 205.4 7.1 3.9e-61 205.4 4.9 5.0 4 2 2 6 6 6 1 I/LWEQ domain ENTH PF01417.15 EMR72087.1 - 5.3e-05 23.0 0.0 0.00024 20.9 0.0 2.2 1 0 0 1 1 1 1 ENTH domain Med15 PF09606.5 EMR72087.1 - 0.5 8.5 36.1 0.8 7.8 25.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Reo_sigmaC PF04582.7 EMR72087.1 - 0.55 9.3 15.5 0.094 11.8 0.4 4.2 1 1 1 4 4 4 0 Reovirus sigma C capsid protein Slu7 PF11708.3 EMR72088.1 - 6.5e-75 251.9 16.2 6.5e-75 251.9 11.2 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EMR72088.1 - 0.024 14.3 0.8 0.043 13.4 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Bud13 PF09736.4 EMR72088.1 - 5.9 7.1 18.6 0.027 14.7 2.3 3.3 3 0 0 3 3 3 0 Pre-mRNA-splicing factor of RES complex Ribosomal_S4 PF00163.14 EMR72089.1 - 2.4e-29 101.5 1.0 5.2e-29 100.4 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EMR72089.1 - 4.3e-13 48.4 1.2 4.3e-13 48.4 0.8 2.3 3 0 0 3 3 3 1 S4 domain DUF2404 PF10296.4 EMR72090.1 - 3.1e-29 100.9 0.0 9e-29 99.4 0.0 1.8 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) LMP PF04778.7 EMR72091.1 - 0.073 12.8 3.9 0.35 10.6 0.3 2.2 2 0 0 2 2 2 0 LMP repeated region TusA PF01206.12 EMR72091.1 - 0.12 11.9 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Sulfurtransferase TusA AAA_23 PF13476.1 EMR72091.1 - 4.2 7.6 8.0 2.5 8.4 3.8 1.7 2 0 0 2 2 2 0 AAA domain Pal1 PF08316.6 EMR72092.1 - 1.9e-46 157.9 1.1 1.9e-46 157.9 0.7 2.0 3 0 0 3 3 3 1 Pal1 cell morphology protein FAD_binding_4 PF01565.18 EMR72093.1 - 2.2e-18 66.0 2.8 3.1e-18 65.5 1.9 1.2 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 EMR72093.1 - 7.1e-09 35.6 1.2 0.00019 21.1 0.1 2.1 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase Methyltransf_23 PF13489.1 EMR72095.1 - 1.9e-11 43.9 0.0 2.5e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR72095.1 - 8.5e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR72095.1 - 2.3e-05 24.9 0.0 3.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR72095.1 - 0.00016 22.0 0.0 0.00027 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR72095.1 - 0.00017 21.9 0.0 0.00027 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EMR72095.1 - 0.00069 18.9 0.0 0.0023 17.2 0.0 1.7 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Fungal_trans PF04082.13 EMR72097.1 - 4.4e-07 29.0 0.2 7.8e-07 28.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR72097.1 - 0.044 13.7 1.7 0.078 12.9 1.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 EMR72098.1 - 4.3e-21 75.5 11.8 1.6e-18 67.1 1.5 3.0 2 1 1 3 3 3 3 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.18 EMR72099.1 - 5.4e-25 87.4 4.8 9.1e-25 86.7 3.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR72099.1 - 2.3e-11 43.4 0.0 4.6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like MMtag PF10159.4 EMR72100.1 - 4e-28 97.2 9.8 5.4e-28 96.8 5.3 2.2 2 1 0 2 2 2 1 Kinase phosphorylation protein FRQ PF09421.5 EMR72100.1 - 1.4 6.5 5.1 1.8 6.2 3.5 1.1 1 0 0 1 1 1 0 Frequency clock protein MFS_1 PF07690.11 EMR72101.1 - 8.7e-32 110.1 58.9 7.8e-28 97.1 29.5 2.7 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR72101.1 - 9e-15 54.1 10.1 2.7e-14 52.6 7.0 1.8 1 0 0 1 1 1 1 Sugar (and other) transporter TGS PF02824.16 EMR72102.1 - 4.4e-20 71.2 0.1 8.5e-20 70.3 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EMR72102.1 - 3.6e-19 68.8 0.2 1.6e-18 66.7 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMR72102.1 - 1.7e-12 46.9 0.0 2.8e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EMR72102.1 - 8.3e-05 22.4 0.3 0.074 12.8 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EMR72102.1 - 0.0098 16.3 0.0 0.023 15.1 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein ArgK PF03308.11 EMR72102.1 - 0.055 12.2 0.1 0.11 11.1 0.1 1.5 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 EMR72102.1 - 0.075 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family ATP_bind_1 PF03029.12 EMR72102.1 - 0.17 11.3 0.9 7.7 5.9 0.1 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein EF1_GNE PF00736.14 EMR72102.1 - 0.17 11.5 1.0 0.59 9.8 0.2 2.2 3 0 0 3 3 3 0 EF-1 guanine nucleotide exchange domain Lactonase PF10282.4 EMR72104.1 - 1.1e-65 222.0 0.0 1.5e-65 221.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PQQ_2 PF13360.1 EMR72104.1 - 0.0026 17.2 0.1 0.0063 16.0 0.2 1.5 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 EMR72104.1 - 0.0035 16.7 0.1 0.079 12.5 0.0 2.8 2 0 0 2 2 2 1 PQQ enzyme repeat LVIVD PF08309.6 EMR72104.1 - 0.17 10.8 0.3 0.39 9.7 0.0 1.8 2 0 0 2 2 2 0 LVIVD repeat UreF PF01730.11 EMR72106.1 - 2.3e-11 43.9 3.4 2.3e-11 43.9 2.4 2.7 2 1 0 2 2 2 1 UreF CENP-B_dimeris PF09026.5 EMR72106.1 - 0.0053 16.9 0.7 0.0053 16.9 0.5 3.1 3 0 0 3 3 3 1 Centromere protein B dimerisation domain DUF3486 PF11985.3 EMR72106.1 - 3 7.8 9.0 3 7.8 4.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) DLH PF01738.13 EMR72107.1 - 1.5e-15 57.1 0.0 1.9e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EMR72107.1 - 3.7e-07 30.0 0.0 4.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR72107.1 - 0.026 14.4 0.4 0.3 10.9 0.2 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF3684 PF12449.3 EMR72108.1 - 0 1381.8 0.0 0 1381.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EMR72108.1 - 1.4e-05 24.7 0.0 3.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Phage_connector PF05352.7 EMR72108.1 - 0.44 9.7 0.0 2.4 7.3 0.0 2.1 2 0 0 2 2 2 0 Phage Connector (GP10) Tub_2 PF04525.7 EMR72109.1 - 5.8e-07 29.0 0.2 9.8e-07 28.3 0.1 1.4 1 1 0 1 1 1 1 Tubby C 2 Sugar_tr PF00083.19 EMR72110.1 - 3.1e-45 154.5 11.3 4.7e-33 114.4 0.3 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR72110.1 - 4.4e-07 28.9 19.8 0.004 15.9 2.2 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Voldacs PF03517.8 EMR72111.1 - 1e-24 86.9 0.2 2.1e-24 85.9 0.1 1.5 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling BBE PF08031.7 EMR72112.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like ADH_zinc_N PF00107.21 EMR72113.1 - 7.2e-09 35.2 0.0 2.3e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR72113.1 - 4.9e-08 32.6 0.0 1.8e-05 24.4 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain tRNA-synt_1e PF01406.14 EMR72114.1 - 1.6e-74 250.7 0.0 1.6e-74 250.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.6 EMR72114.1 - 0.011 15.9 2.1 0.029 14.6 0.0 2.7 2 0 0 2 2 2 0 DALR domain DUF1014 PF06244.7 EMR72114.1 - 6.8 6.9 18.9 3.2 8.0 0.0 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1014) AMP-binding PF00501.23 EMR72115.1 - 1.8e-71 240.7 1.1 7.2e-47 159.7 0.5 2.6 2 1 1 3 3 3 2 AMP-binding enzyme KR PF08659.5 EMR72115.1 - 2.9e-44 150.9 0.4 1.5e-40 138.7 0.0 2.6 2 0 0 2 2 2 2 KR domain NAD_binding_4 PF07993.7 EMR72115.1 - 1.3e-41 142.2 0.0 2.3e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EMR72115.1 - 5e-39 133.8 12.1 2.5e-33 115.3 0.0 4.3 4 1 0 4 4 4 2 short chain dehydrogenase PP-binding PF00550.20 EMR72115.1 - 3.9e-16 59.0 0.0 5.3e-10 39.4 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Condensation PF00668.15 EMR72115.1 - 2.6e-14 52.7 0.3 5.3e-14 51.7 0.1 1.6 2 0 0 2 2 2 1 Condensation domain Epimerase PF01370.16 EMR72115.1 - 1.4e-11 44.2 0.0 6.3e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EMR72115.1 - 9.5e-08 31.0 0.0 3e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 EMR72115.1 - 9.3e-06 26.5 0.1 0.0002 22.2 0.0 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EMR72115.1 - 0.00071 19.8 0.0 0.0027 18.0 0.0 2.1 2 0 0 2 2 2 1 HxxPF-repeated domain NmrA PF05368.8 EMR72115.1 - 0.0045 16.2 0.1 0.011 14.9 0.1 1.7 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR72115.1 - 0.0083 16.1 0.3 0.035 14.0 0.2 2.2 1 0 0 1 1 1 1 NADH(P)-binding KH_3 PF13014.1 EMR72115.1 - 0.089 12.4 1.5 6.8 6.4 0.0 3.6 3 0 0 3 3 3 0 KH domain MFS_1 PF07690.11 EMR72116.1 - 5.4e-35 120.7 57.5 4.7e-34 117.6 39.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EMR72116.1 - 2.1e-18 65.8 19.5 3.2e-18 65.2 13.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMR72116.1 - 6.7e-07 28.2 17.4 6.7e-07 28.2 12.1 3.5 2 1 3 5 5 5 2 Sugar (and other) transporter GCD14 PF08704.5 EMR72117.1 - 0.0001 21.9 1.0 0.0011 18.5 0.0 2.4 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Acyl_transf_1 PF00698.16 EMR72118.1 - 8e-46 156.8 0.0 1.3e-45 156.1 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EMR72118.1 - 3.6e-43 147.8 0.0 9.2e-43 146.4 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 EMR72118.1 - 1e-37 130.0 0.0 3.7e-26 92.1 0.0 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EMR72118.1 - 4.2e-31 107.2 0.0 1.2e-30 105.7 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Cut12 PF11500.3 EMR72119.1 - 4.8e-41 139.9 15.8 4.8e-41 139.9 11.0 4.7 3 1 1 4 4 4 1 Spindle pole body formation-associated protein FlxA PF14282.1 EMR72119.1 - 0.0066 16.3 6.1 0.0066 16.3 4.2 4.6 4 1 1 5 5 5 1 FlxA-like protein DUF2730 PF10805.3 EMR72119.1 - 5.4 6.7 18.4 0.23 11.1 1.4 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) DUF4094 PF13334.1 EMR72119.1 - 9.7 6.6 23.6 0.31 11.4 2.8 4.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) DUF3759 PF12585.3 EMR72120.1 - 4e-40 135.6 4.5 4.7e-40 135.3 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) GatB_Yqey PF02637.13 EMR72120.1 - 0.099 12.3 0.1 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 GatB domain Acyl-CoA_dh_1 PF00441.19 EMR72121.1 - 3.3e-29 101.9 0.4 5.6e-29 101.1 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EMR72121.1 - 8.5e-16 57.2 0.0 1.8e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EMR72121.1 - 2.5e-14 53.6 1.0 5.2e-14 52.6 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EMR72121.1 - 1.5e-12 48.1 0.0 3.1e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain PAF-AH_p_II PF03403.8 EMR72122.1 - 6.3e-40 136.6 0.0 6.9e-35 120.0 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EMR72122.1 - 1.5e-12 47.4 0.1 9.8e-12 44.8 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR72122.1 - 1.8e-05 24.7 9.9 0.00063 19.6 6.9 2.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMR72122.1 - 0.0041 16.0 0.0 0.0076 15.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EMR72122.1 - 0.006 15.4 0.0 0.02 13.7 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase Pkinase PF00069.20 EMR72123.1 - 3.7e-24 85.2 0.0 1.8e-23 83.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR72123.1 - 3.4e-13 49.2 0.0 8.7e-09 34.8 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EMR72123.1 - 0.05 13.3 0.2 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATP_synt_I PF03899.10 EMR72124.1 - 0.12 12.5 1.5 0.16 12.1 0.1 1.9 2 0 0 2 2 2 0 ATP synthase I chain EthD PF07110.6 EMR72125.1 - 6.1e-05 23.8 0.1 9.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 EthD domain LSM PF01423.17 EMR72126.1 - 4.7e-15 54.8 0.2 6.1e-15 54.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain Abhydrolase_6 PF12697.2 EMR72127.1 - 3.8e-08 33.4 0.4 9.5e-08 32.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR72127.1 - 4.4e-07 29.7 0.0 7.8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EMR72127.1 - 0.00027 19.5 0.0 0.0022 16.5 0.0 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EMR72127.1 - 0.00085 18.6 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EMR72127.1 - 0.071 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_M18 PF02127.10 EMR72128.1 - 6.6e-126 420.2 0.0 7.6e-126 420.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) tRNA_synt_2f PF02092.12 EMR72128.1 - 0.13 10.7 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit p450 PF00067.17 EMR72130.1 - 2.4e-64 217.5 0.0 2.8e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HGTP_anticodon2 PF12745.2 EMR72131.1 - 1.7e-61 207.7 2.4 3.6e-35 121.4 0.0 3.7 3 1 1 4 4 4 2 Anticodon binding domain of tRNAs Pkinase PF00069.20 EMR72131.1 - 8.6e-36 123.4 5.3 6.7e-21 74.6 0.0 4.1 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 EMR72131.1 - 3.5e-19 68.8 0.1 2.1e-08 33.5 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 EMR72131.1 - 1.6e-12 47.2 0.0 6.2e-12 45.4 0.0 2.1 1 0 0 1 1 1 1 RWD domain APH PF01636.18 EMR72131.1 - 0.0044 16.7 0.2 0.0044 16.7 0.2 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family YABBY PF04690.8 EMR72131.1 - 0.14 12.4 6.6 0.33 11.1 4.6 1.6 1 0 0 1 1 1 0 YABBY protein RRM_1 PF00076.17 EMR72132.1 - 3.4e-08 33.0 0.0 7.6e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR72132.1 - 3.5e-08 33.1 0.0 1.5e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR72132.1 - 2e-05 24.4 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMR72132.1 - 0.00025 20.7 0.0 0.00055 19.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EMR72132.1 - 0.0015 18.1 0.9 0.0028 17.3 0.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Spo12 PF05032.7 EMR72133.1 - 1.3e-13 50.2 1.4 1.8e-13 49.8 0.2 1.9 2 0 0 2 2 2 1 Spo12 family CENP-R PF06729.7 EMR72133.1 - 0.02 14.5 0.6 0.02 14.5 0.4 1.4 2 0 0 2 2 2 0 Kinetochore component, CENP-R Glyco_hydro_26 PF02156.10 EMR72134.1 - 1.8e-88 297.0 5.7 2.2e-88 296.7 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Aldo_ket_red PF00248.16 EMR72135.1 - 7.3e-55 185.7 0.0 8.8e-55 185.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Death PF00531.17 EMR72135.1 - 9e-05 22.1 0.0 0.49 10.1 0.0 3.2 3 0 0 3 3 3 2 Death domain Glyco_hydro_18 PF00704.23 EMR72136.1 - 4.3e-10 39.5 0.0 7e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 HEAT PF02985.17 EMR72137.1 - 3.2e-18 64.0 9.2 0.00016 21.4 0.1 9.4 10 0 0 10 10 9 3 HEAT repeat HEAT_2 PF13646.1 EMR72137.1 - 7.6e-18 64.5 17.2 0.00028 21.1 0.1 8.3 5 3 4 9 9 8 5 HEAT repeats HEAT_EZ PF13513.1 EMR72137.1 - 3.4e-17 62.3 16.8 9.4e-06 25.9 0.3 11.1 9 3 4 13 13 12 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EMR72137.1 - 2.6e-10 40.5 0.0 0.025 14.9 0.0 5.8 4 2 2 6 6 6 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EMR72137.1 - 2e-07 30.7 0.3 4.2e-06 26.5 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.7 EMR72137.1 - 5.6e-06 26.1 0.0 0.15 11.7 0.0 4.6 3 1 0 4 4 4 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 EMR72137.1 - 8.2e-06 24.4 0.4 1 7.6 0.0 4.8 2 2 2 5 5 5 3 Adaptin N terminal region UME PF08064.8 EMR72137.1 - 1.6e-05 24.7 0.0 0.91 9.5 0.0 5.1 5 0 0 5 5 5 1 UME (NUC010) domain ParcG PF10274.4 EMR72137.1 - 0.00011 22.2 0.6 0.15 11.9 0.0 4.6 3 2 2 5 5 5 1 Parkin co-regulated protein Arm PF00514.18 EMR72137.1 - 0.00095 18.9 9.1 1.3 8.9 0.0 6.8 8 0 0 8 8 6 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 EMR72137.1 - 0.002 16.9 3.0 0.92 8.1 0.0 3.6 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal DUF2454 PF10521.4 EMR72137.1 - 0.0031 16.5 0.4 1.3 7.9 0.1 4.3 3 1 1 4 4 4 1 Protein of unknown function (DUF2454) Vitellogenin_N PF01347.17 EMR72137.1 - 0.0073 14.5 0.2 0.022 13.0 0.0 1.9 2 0 0 2 2 2 1 Lipoprotein amino terminal region DUF2435 PF10363.4 EMR72137.1 - 0.01 15.6 4.4 0.36 10.7 0.1 4.3 4 1 0 4 4 3 0 Protein of unknown function (DUF2435) DUF3384 PF11864.3 EMR72137.1 - 0.012 14.1 0.1 0.027 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) BP28CT PF08146.7 EMR72137.1 - 0.029 14.0 0.0 8.1 6.1 0.1 3.5 4 0 0 4 4 4 0 BP28CT (NUC211) domain YukD PF08817.5 EMR72137.1 - 0.038 14.5 0.1 5.1 7.7 0.0 3.2 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD CLASP_N PF12348.3 EMR72137.1 - 0.091 12.0 0.0 1.3 8.3 0.0 2.9 3 0 0 3 3 3 0 CLASP N terminal ketoacyl-synt PF00109.21 EMR72138.1 - 1.2e-81 274.0 0.0 2.2e-81 273.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EMR72138.1 - 1e-58 199.2 0.3 2.7e-58 197.8 0.1 1.8 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 EMR72138.1 - 9.8e-56 189.0 0.1 1.8e-55 188.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EMR72138.1 - 1.5e-54 184.4 0.1 3.9e-54 183.0 0.0 1.8 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EMR72138.1 - 1.9e-46 158.0 0.0 5.7e-46 156.4 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EMR72138.1 - 1.8e-36 124.5 0.0 4.1e-36 123.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EMR72138.1 - 1.4e-17 63.9 0.0 5.2e-17 62.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EMR72138.1 - 1.4e-17 63.4 0.1 4.7e-17 61.7 0.1 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EMR72138.1 - 1.5e-09 37.7 0.0 4e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR72138.1 - 8.8e-09 35.7 0.0 2.5e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR72138.1 - 4.4e-08 32.8 0.0 1.4e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EMR72138.1 - 9.8e-08 32.1 0.0 2.7e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EMR72138.1 - 3.7e-07 30.6 0.0 1.5e-06 28.7 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 EMR72138.1 - 0.00039 20.1 0.3 0.00086 19.0 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EMR72138.1 - 0.00056 18.9 0.1 0.0011 18.0 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EMR72138.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 EMR72138.1 - 0.44 9.4 0.0 2.8 6.8 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Trp_DMAT PF11991.3 EMR72139.1 - 2.9e-79 266.9 0.0 3.2e-79 266.7 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.17 EMR72142.1 - 2.1e-38 132.0 0.0 2.5e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Chorismate_bind PF00425.13 EMR72143.1 - 4.6e-68 229.3 0.0 1.9e-63 214.1 0.0 2.9 2 1 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.8 EMR72143.1 - 1.8e-16 60.4 0.0 1.3e-15 57.6 0.0 2.5 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region EcKinase PF02958.15 EMR72144.1 - 1.9e-15 56.7 0.0 5.6e-15 55.2 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EMR72144.1 - 6e-10 38.3 0.0 8e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.18 EMR72144.1 - 2.6e-07 30.6 0.5 3.9e-07 30.0 0.4 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HlyIII PF03006.15 EMR72145.1 - 5.1e-31 107.7 21.1 6.7e-31 107.4 14.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF2374 PF09574.5 EMR72145.1 - 0.038 13.6 0.8 0.14 11.8 0.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) ABC2_membrane_5 PF13346.1 EMR72145.1 - 0.28 10.4 5.6 0.18 11.0 2.5 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein p450 PF00067.17 EMR72146.1 - 1.1e-52 179.0 0.0 2.1e-39 135.3 0.0 2.6 1 1 1 2 2 2 2 Cytochrome P450 DUF3237 PF11578.3 EMR72147.1 - 1.4e-14 53.6 0.1 1.9e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) AMP-binding PF00501.23 EMR72148.1 - 7.5e-80 268.3 0.0 9.6e-80 268.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EMR72148.1 - 4.6e-18 65.9 0.0 1.3e-17 64.4 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Serglycin PF04360.7 EMR72148.1 - 2.2 8.0 5.9 0.6 9.8 0.5 2.4 2 0 0 2 2 2 0 Serglycin Gly_transf_sug PF04488.10 EMR72149.1 - 1e-13 51.5 0.0 2.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EMR72149.1 - 0.048 12.1 0.1 4 5.8 0.0 2.3 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain T5orf172 PF10544.4 EMR72150.1 - 0.029 14.7 0.4 0.047 14.0 0.3 1.4 1 0 0 1 1 1 0 T5orf172 domain ATP-synt_B PF00430.13 EMR72150.1 - 0.28 10.9 9.0 0.38 10.5 6.2 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Nop53 PF07767.6 EMR72150.1 - 1.5 7.7 9.9 2 7.3 6.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Dysbindin PF04440.11 EMR72150.1 - 1.9 8.2 5.8 2.1 8.1 0.2 2.1 1 1 1 2 2 2 0 Dysbindin (Dystrobrevin binding protein 1) Agouti PF05039.7 EMR72150.1 - 2.6 8.4 5.1 7.1 7.0 0.7 2.2 2 0 0 2 2 2 0 Agouti protein PAD PF03068.10 EMR72151.1 - 3.8e-49 167.1 0.0 5.5e-48 163.3 0.0 2.0 1 1 0 1 1 1 1 Protein-arginine deiminase (PAD) Clc-like PF07062.7 EMR72152.1 - 0.076 12.2 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Clc-like adh_short PF00106.20 EMR72153.1 - 9.1e-23 80.9 7.7 1.3e-22 80.4 5.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR72153.1 - 2.3e-11 43.6 3.0 3.3e-11 43.1 2.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR72153.1 - 2.2e-09 37.4 0.2 2.9e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EMR72153.1 - 0.0016 18.1 0.8 0.011 15.4 0.7 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EMR72153.1 - 0.0062 15.9 1.3 0.014 14.8 0.9 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Rad4 PF03835.10 EMR72154.1 - 5e-16 58.3 0.7 5e-16 58.3 0.5 1.7 1 1 1 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EMR72154.1 - 3.5e-08 33.6 3.7 6.2e-08 32.8 2.6 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily p450 PF00067.17 EMR72155.1 - 2.6e-40 138.3 0.0 3.4e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EMR72157.1 - 8.8e-31 106.9 0.0 1.1e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lyase_1 PF00206.15 EMR72158.1 - 2.2e-30 105.9 0.1 9.6e-30 103.8 0.0 1.9 1 1 1 2 2 2 1 Lyase ADSL_C PF10397.4 EMR72158.1 - 1.1e-14 54.1 0.0 3.5e-13 49.3 0.0 2.4 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus CAF-1_p150 PF11600.3 EMR72159.1 - 0.00052 19.4 2.5 0.00074 18.9 1.7 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3450 PF11932.3 EMR72159.1 - 0.0059 15.8 5.9 0.0077 15.5 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HOOK PF05622.7 EMR72159.1 - 0.012 13.4 0.1 0.014 13.2 0.1 1.0 1 0 0 1 1 1 0 HOOK protein DUF1875 PF08961.5 EMR72159.1 - 0.031 13.5 0.2 0.041 13.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) DUF4140 PF13600.1 EMR72159.1 - 0.049 14.0 2.1 0.076 13.4 1.5 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) bZIP_Maf PF03131.12 EMR72159.1 - 0.43 10.9 7.2 0.7 10.2 5.0 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor CFEM PF05730.6 EMR72161.1 - 2.1e-07 30.6 9.1 4.2e-07 29.6 6.3 1.5 1 0 0 1 1 1 1 CFEM domain Fungal_trans PF04082.13 EMR72162.1 - 2.2e-06 26.7 0.0 3.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Destabilase PF05497.7 EMR72162.1 - 0.24 11.5 0.0 0.62 10.1 0.0 1.6 2 0 0 2 2 2 0 Destabilase Sugar_tr PF00083.19 EMR72163.1 - 1.1e-89 301.1 23.2 1.3e-89 300.9 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR72163.1 - 1.9e-23 82.8 22.4 1.9e-23 82.8 15.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2 PF04550.7 EMR72163.1 - 0.00056 19.9 1.4 0.0018 18.2 1.0 1.8 1 0 0 1 1 1 1 Phage holin family 2 TRI12 PF06609.8 EMR72163.1 - 0.00084 17.6 0.6 0.00084 17.6 0.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-RNPHF PF08080.7 EMR72163.1 - 0.027 13.9 1.3 0.95 9.0 0.1 2.5 2 0 0 2 2 2 0 RNPHF zinc finger ALIX_LYPXL_bnd PF13949.1 EMR72164.1 - 0.08 11.8 1.1 0.14 11.1 0.8 1.4 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Toxin_21 PF08091.6 EMR72164.1 - 5.1 6.8 11.8 6.3 6.6 2.0 2.4 2 0 0 2 2 2 0 Spider insecticidal peptide Glyco_hydro_43 PF04616.9 EMR72165.1 - 2.5e-26 92.4 0.8 3.2e-26 92.0 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Amidohydro_4 PF13147.1 EMR72166.1 - 3.6e-15 56.7 16.1 6.8e-15 55.8 11.1 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EMR72166.1 - 9e-13 48.5 0.6 4.7e-11 42.9 0.4 2.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EMR72166.1 - 1.1e-11 44.3 0.1 3.6e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EMR72166.1 - 6.2e-05 22.3 16.2 0.0011 18.3 6.8 2.5 1 1 1 2 2 2 2 Amidohydrolase family Peptidase_S8 PF00082.17 EMR72167.1 - 5.1e-08 32.4 0.0 7.6e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Gamma-thionin PF00304.15 EMR72168.1 - 0.35 10.9 11.3 0.24 11.4 1.8 2.3 2 0 0 2 2 2 0 Gamma-thionin family Nodulin_late PF07127.6 EMR72168.1 - 2.6 8.2 5.4 6 7.0 0.8 2.3 2 0 0 2 2 2 0 Late nodulin protein Toxin_29 PF08116.6 EMR72168.1 - 5.5 6.8 15.3 3.9 7.3 4.1 2.9 2 0 0 2 2 2 0 PhTx neurotoxin family Toxin_11 PF07473.6 EMR72168.1 - 7.3 6.5 10.6 2.7 7.9 1.7 2.5 2 0 0 2 2 2 0 Spasmodic peptide gm9a Glt_symporter PF03616.9 EMR72169.1 - 0.0036 15.8 0.8 0.0049 15.4 0.6 1.2 1 0 0 1 1 1 1 Sodium/glutamate symporter MFS_1 PF07690.11 EMR72169.1 - 0.015 14.0 5.0 0.019 13.6 3.4 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF4131 PF13567.1 EMR72169.1 - 1.9 7.8 4.7 4.5 6.6 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) Amino_oxidase PF01593.19 EMR72170.1 - 3.9e-29 102.0 0.6 6.7e-28 97.9 0.4 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EMR72170.1 - 1.8e-07 31.0 0.0 3.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR72170.1 - 0.00054 20.0 0.0 0.0015 18.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR72170.1 - 0.00082 19.7 0.4 0.0025 18.2 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EMR72170.1 - 0.0057 15.7 0.2 0.0094 15.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR72170.1 - 0.009 14.9 0.7 0.018 13.9 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Laminin_N PF00055.12 EMR72172.1 - 0.071 12.0 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Laminin N-terminal (Domain VI) p450 PF00067.17 EMR72173.1 - 4e-54 183.8 0.2 1.7e-31 109.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 EMR72174.1 - 4.3e-21 75.0 24.8 5.2e-21 74.7 17.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily NOGCT PF08155.6 EMR72175.1 - 2.6e-28 97.4 2.5 5.1e-28 96.5 1.7 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EMR72175.1 - 1.7e-17 63.0 1.6 5.1e-17 61.4 1.1 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EMR72175.1 - 5.5e-15 55.3 0.0 1.2e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EMR72175.1 - 8.5e-09 34.8 0.0 1.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EMR72175.1 - 0.0095 15.7 1.2 3.2 7.5 0.0 2.8 2 1 1 3 3 3 2 Dynamin family Miro PF08477.8 EMR72175.1 - 0.025 15.0 0.0 0.065 13.7 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 EMR72175.1 - 0.06 13.5 0.1 1.8 8.6 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.1 EMR72175.1 - 0.56 10.4 4.2 24 5.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain adh_short PF00106.20 EMR72176.1 - 1.7e-14 54.0 1.2 3.7e-14 52.9 0.8 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR72176.1 - 5.4e-08 32.7 0.4 7.5e-08 32.2 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR72176.1 - 0.00024 20.5 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase PF01370.16 EMR72177.1 - 8.2e-13 48.3 1.4 5.2e-06 26.0 0.4 2.6 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EMR72177.1 - 3e-12 46.2 0.4 6e-12 45.3 0.3 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR72177.1 - 1.7e-11 44.4 0.3 2.8e-11 43.7 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMR72177.1 - 0.0028 17.6 1.4 0.0078 16.1 1.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR72177.1 - 0.0054 16.4 0.9 0.011 15.4 0.6 1.5 1 1 0 1 1 1 1 KR domain GARS_N PF02844.10 EMR72177.1 - 0.0071 16.7 0.1 0.014 15.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain DapB_N PF01113.15 EMR72177.1 - 0.028 14.3 0.7 0.11 12.4 0.1 2.0 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 EMR72177.1 - 0.046 12.6 1.4 0.66 8.8 0.1 2.4 2 1 0 2 2 2 0 RmlD substrate binding domain Pribosyltran PF00156.22 EMR72178.1 - 7.7e-16 57.9 0.1 2.1e-15 56.5 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain DUF3186 PF11382.3 EMR72178.1 - 0.02 14.0 0.2 0.028 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) DUF3446 PF11928.3 EMR72178.1 - 0.57 10.4 7.0 0.87 9.8 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Acetyltransf_1 PF00583.19 EMR72179.1 - 2.3e-10 40.3 0.0 4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR72179.1 - 7.2e-07 29.2 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR72179.1 - 0.0083 16.2 0.0 0.024 14.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EMR72179.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ADH_zinc_N PF00107.21 EMR72180.1 - 7.1e-12 45.0 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR72180.1 - 5.6e-08 32.5 0.1 1.8e-07 30.8 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NmrA PF05368.8 EMR72182.1 - 1.1e-10 41.1 0.0 1.6e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR72182.1 - 1.8e-10 41.1 0.0 2.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EMR72182.1 - 9.5e-05 21.9 0.2 0.00018 21.0 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EMR72182.1 - 0.0002 21.3 0.1 0.00038 20.4 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR72182.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 KR domain CbiJ PF02571.9 EMR72182.1 - 0.059 12.6 0.2 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK GARS_N PF02844.10 EMR72182.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain TrkA_N PF02254.13 EMR72182.1 - 0.16 11.9 0.7 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain COesterase PF00135.23 EMR72183.1 - 1.4e-15 57.0 0.0 1.9e-09 36.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family LIP PF03583.9 EMR72184.1 - 5e-17 62.0 3.3 2.9e-16 59.5 2.3 2.0 1 1 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 EMR72184.1 - 3.3e-12 46.7 0.8 5.8e-12 45.9 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR72184.1 - 1.1e-11 44.6 0.7 2.7e-11 43.3 0.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR72184.1 - 0.0011 18.1 1.0 1.9 7.6 0.9 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EMR72184.1 - 0.022 14.3 0.7 0.61 9.5 0.0 2.6 3 0 0 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EMR72184.1 - 0.063 13.1 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 TAP-like protein CH PF00307.26 EMR72185.1 - 7.5e-58 193.2 0.0 2.2e-15 56.6 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EMR72185.1 - 2.1e-06 27.7 2.1 1.4e-05 25.1 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EMR72185.1 - 0.0016 17.6 1.3 0.4 10.1 0.2 3.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EMR72185.1 - 0.0051 16.5 0.5 0.12 12.3 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain CAMSAP_CH PF11971.3 EMR72185.1 - 0.031 13.9 0.0 67 3.2 0.0 4.0 4 0 0 4 4 4 0 CAMSAP CH domain MFS_1 PF07690.11 EMR72186.1 - 1.2e-46 159.0 29.1 7.5e-45 153.1 18.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR72186.1 - 1.2e-11 43.8 27.3 9.6e-11 40.9 18.9 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EMR72186.1 - 2.5e-11 42.6 8.4 0.0001 20.8 0.0 4.6 3 2 1 4 4 4 3 MFS/sugar transport protein TRI12 PF06609.8 EMR72186.1 - 8.6e-06 24.2 4.8 1.4e-05 23.5 3.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 EMR72186.1 - 0.0007 18.3 2.0 0.0007 18.3 1.4 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF791) MFS_3 PF05977.8 EMR72186.1 - 0.0018 16.4 8.8 0.0018 16.4 6.1 1.7 2 1 0 2 2 2 1 Transmembrane secretion effector DUF2215 PF10225.4 EMR72186.1 - 0.038 13.4 2.1 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) Transgly_assoc PF04226.8 EMR72186.1 - 0.79 9.8 12.0 2.2 8.4 3.9 3.5 2 0 0 2 2 2 0 Transglycosylase associated protein UPF0546 PF10639.4 EMR72187.1 - 9.9e-31 105.8 0.0 1.8e-30 105.0 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 DUF485 PF04341.7 EMR72187.1 - 0.05 13.3 0.0 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Methyltransf_12 PF08242.7 EMR72188.1 - 0.00016 22.1 0.0 0.00034 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR72188.1 - 0.0028 17.4 0.0 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR72188.1 - 0.01 16.3 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMR72188.1 - 0.019 15.4 0.0 0.047 14.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain GMC_oxred_C PF05199.8 EMR72189.1 - 5.9e-25 88.2 0.4 1.2e-24 87.2 0.3 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR72189.1 - 6.5e-23 81.3 0.0 1.5e-22 80.1 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EMR72189.1 - 5.4e-06 25.5 0.4 0.00065 18.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR72189.1 - 0.00023 20.2 0.2 0.00062 18.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase DOMON PF03351.12 EMR72189.1 - 0.00062 19.6 0.1 0.0021 17.9 0.0 1.9 2 0 0 2 2 1 1 DOMON domain DUF3446 PF11928.3 EMR72189.1 - 0.0012 18.9 0.5 0.0047 17.0 0.4 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3446) NAD_binding_8 PF13450.1 EMR72189.1 - 0.0023 17.9 0.0 0.0066 16.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EMR72189.1 - 0.0054 15.2 0.1 0.0099 14.3 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EMR72189.1 - 0.0057 16.7 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR72189.1 - 0.0079 16.0 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR72189.1 - 0.016 14.3 0.1 0.031 13.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 EMR72189.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.7 EMR72189.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Glyco_hydro_61 PF03443.9 EMR72190.1 - 5.3e-41 140.8 0.3 6.4e-41 140.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF2771 PF10969.3 EMR72191.1 - 0.039 13.2 0.1 0.092 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2771) MBOAT PF03062.14 EMR72192.1 - 1.5e-34 119.5 18.9 1.5e-34 119.5 13.1 2.1 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EMR72192.1 - 9.1e-06 25.6 2.2 2.8e-05 24.0 1.6 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family C2 PF00168.25 EMR72193.1 - 1.8e-13 50.1 0.1 4.2e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF3668 PF12416.3 EMR72193.1 - 0.04 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Cep120 protein Auxin_canalis PF05703.6 EMR72194.1 - 0.063 13.0 1.2 0.12 12.1 0.6 1.7 1 1 1 2 2 2 0 Auxin canalisation Hydrolase_6 PF13344.1 EMR72195.1 - 8.7e-25 86.5 0.0 1.9e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR72195.1 - 1.3e-14 53.6 0.1 7e-14 51.2 0.1 2.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EMR72195.1 - 4.4e-05 23.7 0.3 0.012 15.8 0.0 3.5 3 1 1 4 4 4 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR72195.1 - 0.00013 22.4 0.8 0.044 14.1 0.0 2.8 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HMG_box PF00505.14 EMR72196.1 - 9.8e-08 32.1 0.4 2e-07 31.1 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMR72196.1 - 0.037 14.4 1.5 0.044 14.1 0.2 1.8 2 0 0 2 2 2 0 HMG-box domain WSC PF01822.14 EMR72198.1 - 3e-34 116.8 24.6 2.7e-17 62.4 6.0 2.2 2 0 0 2 2 2 2 WSC domain DTHCT PF08070.6 EMR72198.1 - 0.12 13.0 0.1 0.18 12.4 0.1 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region NAD_binding_6 PF08030.7 EMR72199.1 - 3.4e-20 72.5 0.0 5.5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EMR72199.1 - 2.5e-19 69.5 7.8 5.9e-19 68.3 5.4 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EMR72199.1 - 3.6e-11 42.8 0.0 9e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EMR72199.1 - 5.6e-08 33.3 0.0 2.6e-05 24.7 0.0 2.4 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain adh_short PF00106.20 EMR72200.1 - 2e-14 53.8 0.9 2.7e-14 53.4 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR72200.1 - 3.9e-07 29.9 0.6 5.4e-07 29.4 0.4 1.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR72200.1 - 7.9e-05 22.5 0.0 9.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR72200.1 - 0.037 13.4 0.1 0.13 11.6 0.1 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR72200.1 - 0.096 12.6 1.7 0.38 10.7 1.2 2.1 1 1 0 1 1 1 0 NADH(P)-binding CPDase PF07823.6 EMR72201.1 - 4.2e-34 117.7 0.0 4.7e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EMR72201.1 - 0.00058 19.6 0.0 0.2 11.3 0.0 2.4 2 1 0 2 2 2 2 2'-5' RNA ligase superfamily HMG_box PF00505.14 EMR72202.1 - 1.1e-15 57.6 1.1 1.8e-15 56.9 0.8 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EMR72202.1 - 4.2e-08 33.4 0.9 6.6e-08 32.8 0.6 1.3 1 0 0 1 1 1 1 HMG-box domain Ctr PF04145.10 EMR72203.1 - 1.5e-43 148.2 0.4 1.8e-43 148.0 0.3 1.0 1 0 0 1 1 1 1 Ctr copper transporter family SK_channel PF03530.9 EMR72203.1 - 0.0036 17.1 0.1 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 Calcium-activated SK potassium channel SCIMP PF15050.1 EMR72203.1 - 0.0095 15.8 0.1 0.017 14.9 0.0 1.4 2 0 0 2 2 2 1 SCIMP protein GMC_oxred_N PF00732.14 EMR72204.1 - 2e-16 59.9 0.1 1.3e-15 57.2 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EMR72204.1 - 4.6e-06 26.9 0.0 7.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Abhydrolase_5 PF12695.2 EMR72205.1 - 2.3e-15 56.6 0.0 5.2e-13 48.9 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR72205.1 - 1.2e-08 35.1 0.9 2.7e-08 33.9 0.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR72205.1 - 1.9e-05 23.9 0.1 0.00012 21.4 0.1 2.0 1 1 1 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 EMR72205.1 - 0.00013 21.3 0.1 0.0022 17.2 0.0 2.3 1 1 1 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 EMR72205.1 - 0.0024 17.6 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1100 PF06500.6 EMR72205.1 - 0.023 13.3 0.0 0.035 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.7 EMR72205.1 - 0.046 12.2 0.0 0.083 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) UPF0227 PF05728.7 EMR72205.1 - 0.082 12.6 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Peptidase_S15 PF02129.13 EMR72205.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FMN_dh PF01070.13 EMR72206.1 - 1.3e-108 363.0 0.1 1.5e-108 362.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EMR72206.1 - 0.00019 20.4 0.7 0.00027 19.9 0.5 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EMR72206.1 - 0.0024 17.1 1.2 0.0037 16.4 0.8 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 EMR72206.1 - 0.0045 16.0 0.5 0.56 9.2 0.2 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EMR72206.1 - 0.0051 15.7 0.2 0.0073 15.2 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EMR72206.1 - 0.0056 15.9 0.6 0.15 11.3 0.1 2.6 2 1 1 3 3 3 1 Histidine biosynthesis protein Ytp1 PF10355.4 EMR72207.1 - 1.2e-83 280.4 11.2 1.5e-83 280.1 7.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2339 PF10101.4 EMR72207.1 - 0.00053 18.4 3.3 0.00069 18.0 2.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) Ni_hydr_CYTB PF01292.15 EMR72207.1 - 0.0026 17.1 5.4 0.0026 17.1 3.7 3.0 1 1 1 2 2 2 1 Prokaryotic cytochrome b561 p450 PF00067.17 EMR72208.1 - 4.8e-23 81.4 0.0 7.9e-23 80.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 HET PF06985.6 EMR72209.1 - 4.4e-25 88.4 0.0 7.4e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD-oxidase_C PF02913.14 EMR72211.1 - 4.2e-60 203.1 0.4 6.8e-60 202.4 0.3 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EMR72211.1 - 2.7e-35 120.8 0.0 5.4e-35 119.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_18 PF00704.23 EMR72211.1 - 1.5e-12 47.6 0.0 2.6e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1754 PF08555.5 EMR72213.1 - 1.3e-07 32.1 26.0 7.4e-06 26.4 18.0 2.4 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CENP-B_dimeris PF09026.5 EMR72213.1 - 0.11 12.7 4.3 0.16 12.2 3.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3827 PF12877.2 EMR72213.1 - 0.26 9.3 4.4 0.31 9.0 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Laps PF10169.4 EMR72213.1 - 0.47 10.6 12.2 0.73 10.0 8.4 1.5 1 1 0 1 1 1 0 Learning-associated protein POX PF07526.6 EMR72213.1 - 7.9 6.7 9.7 1.2 9.3 3.1 1.9 1 1 1 2 2 2 0 Associated with HOX TMEM154 PF15102.1 EMR72213.1 - 7.9 6.1 6.8 1.4 8.6 1.2 1.9 2 0 0 2 2 2 0 TMEM154 protein family C6 PF01681.12 EMR72214.1 - 1.9 8.6 8.3 0.55 10.3 2.9 2.2 2 1 0 2 2 2 0 C6 domain SK_channel PF03530.9 EMR72215.1 - 2.2 8.1 8.2 0.47 10.2 1.2 2.3 1 1 1 2 2 2 0 Calcium-activated SK potassium channel adh_short_C2 PF13561.1 EMR72216.1 - 4.4e-22 79.0 0.0 1.3e-21 77.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR72216.1 - 1.4e-18 67.3 0.6 7.3e-17 61.7 0.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR72216.1 - 0.00014 21.6 0.1 0.00044 19.9 0.0 1.7 2 0 0 2 2 2 1 KR domain TFIIB PF00382.14 EMR72216.1 - 0.033 14.0 0.3 0.52 10.1 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat DUF1776 PF08643.5 EMR72216.1 - 0.17 11.0 0.1 0.27 10.3 0.0 1.3 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Asp PF00026.18 EMR72218.1 - 1.7e-64 218.0 0.4 2.5e-64 217.5 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMR72218.1 - 2.8e-05 24.1 0.0 0.00021 21.2 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal F-box-like PF12937.2 EMR72220.1 - 9.9e-09 34.7 0.3 3.8e-08 32.9 0.2 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMR72220.1 - 0.0038 16.8 1.5 0.44 10.2 0.1 2.6 2 0 0 2 2 2 2 F-box domain EamA PF00892.15 EMR72221.1 - 3.5e-09 36.7 31.2 5.6e-06 26.4 1.3 2.7 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EMR72221.1 - 2.8e-07 30.7 20.5 1.1e-05 25.5 0.1 2.6 2 0 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 EMR72221.1 - 0.0037 16.9 17.3 0.011 15.4 6.1 2.7 3 0 0 3 3 3 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EMR72221.1 - 0.02 14.0 5.8 0.12 11.4 0.0 2.4 2 0 0 2 2 2 0 Nucleotide-sugar transporter CDC45 PF02724.9 EMR72221.1 - 0.074 11.0 1.9 0.11 10.5 1.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EMR72221.1 - 1.6 6.5 8.3 2.1 6.1 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family Aldo_ket_red PF00248.16 EMR72222.1 - 9e-52 175.6 0.0 1e-51 175.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 5_nucleotid_C PF02872.13 EMR72223.1 - 3.4e-37 127.8 0.0 1.6e-35 122.3 0.0 2.2 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EMR72223.1 - 9.8e-09 34.8 0.1 1.6e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Abhydrolase_3 PF07859.8 EMR72224.1 - 2.7e-23 82.6 0.0 2.4e-22 79.5 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR72224.1 - 0.0027 17.4 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EMR72224.1 - 0.032 13.4 0.0 0.07 12.3 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family AAA PF00004.24 EMR72225.1 - 1.9e-10 41.0 0.0 4.9e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EMR72225.1 - 3.6e-05 23.9 0.0 0.00012 22.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMR72225.1 - 6.6e-05 22.5 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EMR72225.1 - 0.00016 21.7 0.0 0.00024 21.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EMR72225.1 - 0.0022 18.8 0.1 0.0067 17.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMR72225.1 - 0.0026 17.4 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EMR72225.1 - 0.0029 17.2 0.2 0.005 16.4 0.2 1.6 1 1 0 1 1 1 1 AAA domain Torsin PF06309.6 EMR72225.1 - 0.0062 16.4 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Torsin IstB_IS21 PF01695.12 EMR72225.1 - 0.0073 15.7 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EMR72225.1 - 0.0088 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EMR72225.1 - 0.0094 15.8 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EMR72225.1 - 0.011 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EMR72225.1 - 0.025 14.4 0.0 0.076 12.9 0.0 1.8 1 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EMR72225.1 - 0.029 13.8 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 EMR72225.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EMR72225.1 - 0.074 12.2 0.5 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein RuvB_N PF05496.7 EMR72225.1 - 0.082 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EMR72225.1 - 0.31 10.9 2.6 1.1 9.1 0.1 2.6 2 1 1 3 3 3 0 AAA domain DUF148 PF02520.12 EMR72226.1 - 0.012 15.3 1.3 0.028 14.2 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF148 Cep57_MT_bd PF06657.8 EMR72226.1 - 0.031 14.1 3.3 0.073 13.0 2.3 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 AIF-MLS PF14962.1 EMR72226.1 - 0.08 12.5 5.4 0.48 10.0 0.0 2.5 2 1 0 2 2 2 0 Mitochondria Localisation Sequence AAA_13 PF13166.1 EMR72226.1 - 0.12 10.8 4.8 0.16 10.4 3.3 1.1 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EMR72226.1 - 4.1 6.9 7.8 3.4 7.2 4.4 1.7 2 0 0 2 2 2 0 IncA protein YlqD PF11068.3 EMR72226.1 - 8.2 6.4 11.7 0.89 9.6 4.9 1.7 2 0 0 2 2 2 0 YlqD protein Peptidase_C30 PF05409.8 EMR72227.1 - 6.9 5.6 7.5 11 4.9 5.2 1.2 1 0 0 1 1 1 0 Coronavirus endopeptidase C30 Ank PF00023.25 EMR72228.1 - 3.4e-19 67.6 1.1 8.3e-08 31.6 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EMR72228.1 - 6.1e-16 58.5 0.5 6e-06 26.5 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EMR72228.1 - 2e-13 50.1 0.5 1.9e-07 31.1 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR72228.1 - 4.6e-12 46.1 1.5 0.00039 20.8 0.4 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR72228.1 - 2.1e-09 36.6 0.4 0.015 15.5 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EMR72228.1 - 6.9e-06 25.6 0.1 4.1e-05 23.1 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain SnAC PF14619.1 EMR72228.1 - 0.31 11.2 3.9 0.23 11.6 0.7 2.3 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex Ribosomal_S24e PF01282.14 EMR72230.1 - 3.4e-33 113.2 0.0 5.5e-33 112.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Amino_oxidase PF01593.19 EMR72231.1 - 3.1e-51 174.8 0.0 3.9e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.16 EMR72231.1 - 3.1e-17 62.4 0.2 5.6e-17 61.6 0.1 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.1 EMR72231.1 - 5.7e-11 42.2 0.3 5.7e-11 42.2 0.2 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMR72231.1 - 2.2e-07 30.0 0.3 4.3e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EMR72231.1 - 5.6e-07 28.7 1.7 0.00069 18.6 0.4 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR72231.1 - 2e-06 28.0 0.5 0.0039 17.2 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR72231.1 - 2e-05 23.6 0.4 0.01 14.8 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.2 EMR72231.1 - 2.4e-05 23.6 3.9 3.7e-05 22.9 2.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR72231.1 - 4e-05 22.2 2.0 0.0026 16.2 0.4 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EMR72231.1 - 0.001 18.9 0.4 0.004 17.0 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR72231.1 - 0.0019 17.3 0.6 0.004 16.2 0.4 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EMR72231.1 - 0.026 14.9 1.2 0.07 13.5 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EMR72231.1 - 0.029 13.2 2.5 0.031 13.1 0.6 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EMR72231.1 - 0.3 10.0 2.6 0.77 8.7 1.0 2.0 2 0 0 2 2 2 0 FAD binding domain Pkinase PF00069.20 EMR72233.1 - 4.5e-72 242.3 0.0 5.3e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR72233.1 - 2.3e-31 108.8 0.0 3.2e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMR72233.1 - 0.021 14.5 0.1 0.07 12.8 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EMR72233.1 - 0.047 13.0 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 EMR72233.1 - 0.093 11.7 0.1 0.28 10.2 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dioxygenase_C PF00775.16 EMR72234.1 - 1.8e-11 43.6 0.2 3.6e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 Dioxygenase ABC_membrane PF00664.18 EMR72236.1 - 1.9e-53 181.6 31.4 2.2e-33 115.8 8.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EMR72236.1 - 1.6e-52 177.4 0.1 9.3e-30 103.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EMR72236.1 - 5.3e-07 29.8 0.6 0.51 10.2 0.5 4.4 2 2 0 3 3 3 2 AAA domain SMC_N PF02463.14 EMR72236.1 - 2.4e-06 26.9 4.7 0.043 13.0 0.6 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 EMR72236.1 - 2.4e-05 24.8 0.7 0.049 14.1 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EMR72236.1 - 2.8e-05 24.1 1.6 0.019 14.9 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EMR72236.1 - 3e-05 23.9 0.7 0.21 11.5 0.2 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EMR72236.1 - 0.0001 21.7 1.7 0.39 10.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EMR72236.1 - 0.00018 20.9 0.7 0.14 11.5 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EMR72236.1 - 0.00029 21.6 3.1 0.59 10.9 0.5 3.5 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EMR72236.1 - 0.00033 19.8 1.0 0.078 12.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EMR72236.1 - 0.0013 17.9 0.4 1.2 8.1 0.0 2.6 3 0 0 3 3 3 2 Zeta toxin T2SE PF00437.15 EMR72236.1 - 0.0021 17.0 0.0 0.53 9.1 0.0 2.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.1 EMR72236.1 - 0.0021 18.3 0.0 3.7 7.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EMR72236.1 - 0.0076 16.3 1.2 2.3 8.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EMR72236.1 - 0.0089 15.5 0.0 2.4 7.5 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 EMR72236.1 - 0.032 13.6 0.3 1.5 8.2 0.1 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EMR72236.1 - 0.059 12.9 0.8 1.5 8.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EMR72236.1 - 0.14 11.9 3.4 0.86 9.3 0.2 2.7 2 0 0 2 2 2 0 Dynamin family Peptidase_M23 PF01551.17 EMR72236.1 - 0.15 12.0 0.1 41 4.3 0.0 3.4 3 0 0 3 3 3 0 Peptidase family M23 MobB PF03205.9 EMR72236.1 - 0.25 11.0 1.0 4.1 7.1 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EMR72236.1 - 0.26 11.2 2.0 0.68 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EMR72236.1 - 0.3 10.8 5.8 1.2 8.8 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_23 PF13476.1 EMR72236.1 - 0.32 11.3 8.5 2.1 8.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain UPF0079 PF02367.12 EMR72236.1 - 0.41 10.2 2.6 0.69 9.5 0.3 2.3 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 EMR72236.1 - 0.67 9.3 2.8 0.37 10.2 0.2 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Meth_synt_2 PF01717.13 EMR72237.1 - 3.8e-14 52.4 0.0 9.2e-13 47.8 0.0 2.1 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EMR72237.1 - 0.022 14.0 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain FtsJ PF01728.14 EMR72238.1 - 4.5e-16 59.3 0.0 8e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EMR72238.1 - 7.5e-05 23.2 0.0 0.0003 21.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR72238.1 - 0.011 15.4 0.0 0.03 14.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Nol1_Nop2_Fmu PF01189.12 EMR72238.1 - 0.091 12.1 0.0 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 NOL1/NOP2/sun family Methyltransf_23 PF13489.1 EMR72239.1 - 1.5e-15 57.2 0.0 2.2e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR72239.1 - 2.2e-10 40.3 0.0 4.1e-09 36.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR72239.1 - 6.6e-10 39.5 0.0 2.5e-08 34.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR72239.1 - 1.6e-08 34.8 0.0 5.4e-08 33.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR72239.1 - 5.8e-08 33.1 0.0 3.6e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR72239.1 - 5.6e-05 23.1 0.0 0.00014 21.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EMR72239.1 - 0.00014 21.0 0.0 0.00057 18.9 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EMR72239.1 - 0.00062 20.0 0.0 0.003 17.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EMR72239.1 - 0.0013 18.1 0.0 0.0078 15.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EMR72239.1 - 0.0026 16.9 0.0 0.0048 16.1 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase CheR PF01739.13 EMR72239.1 - 0.0031 16.8 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain FtsJ PF01728.14 EMR72239.1 - 0.0046 16.9 0.0 0.0069 16.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EMR72239.1 - 0.0053 15.9 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EMR72239.1 - 0.0066 15.5 0.0 0.018 14.1 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EMR72239.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EMR72239.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Sulfatase PF00884.18 EMR72240.1 - 3.2e-40 138.2 0.2 1.7e-23 83.2 0.0 2.2 1 1 1 2 2 2 2 Sulfatase Phosphodiest PF01663.17 EMR72240.1 - 0.00031 20.1 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Ndr PF03096.9 EMR72240.1 - 0.07 11.6 0.0 0.57 8.6 0.0 2.0 2 0 0 2 2 2 0 Ndr family Stirrup PF09061.1 EMR72240.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Stirrup Methyltransf_11 PF08241.7 EMR72241.1 - 2.4e-13 50.3 0.0 4e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR72241.1 - 1.3e-09 37.5 0.0 4.9e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EMR72241.1 - 2.1e-09 37.7 0.0 4.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR72241.1 - 1.4e-07 31.3 0.0 2.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR72241.1 - 3e-07 30.7 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR72241.1 - 3.1e-07 30.1 0.0 4.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR72241.1 - 0.0003 21.3 0.0 0.00082 19.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EMR72241.1 - 0.0006 19.2 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MFS_1 PF07690.11 EMR72243.1 - 7.7e-31 107.0 28.8 7.7e-31 107.0 20.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EMR72243.1 - 0.013 15.2 1.8 0.029 14.1 0.2 2.4 2 0 0 2 2 2 0 MFS_1 like family DUF2583 PF10762.4 EMR72243.1 - 6 7.0 6.2 11 6.2 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2583) NAD_binding_8 PF13450.1 EMR72244.1 - 1.8e-10 40.6 0.0 3.9e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EMR72244.1 - 1.9e-08 33.8 0.0 9.8e-07 28.1 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EMR72244.1 - 4.3e-07 30.1 0.2 5.3e-06 26.6 0.0 2.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR72244.1 - 0.00083 19.2 0.0 0.0096 15.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR72244.1 - 0.0019 17.3 0.2 0.0037 16.4 0.0 1.5 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EMR72244.1 - 0.0055 15.8 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EMR72244.1 - 0.01 15.6 0.1 0.065 12.9 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EMR72244.1 - 0.015 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 EMR72244.1 - 0.016 14.1 0.0 0.032 13.1 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR72244.1 - 0.019 13.4 0.0 0.03 12.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.13 EMR72244.1 - 0.02 14.9 0.0 0.077 12.9 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain DUF1344 PF07076.6 EMR72244.1 - 0.083 12.4 0.1 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) FAD_binding_2 PF00890.19 EMR72244.1 - 0.096 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EMR72244.1 - 0.13 11.1 0.1 0.22 10.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DUF3455 PF11937.3 EMR72245.1 - 9e-27 94.1 0.0 1.3e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) FPN1 PF06963.7 EMR72246.1 - 2.6e-97 325.9 13.4 1e-60 205.3 2.4 2.0 1 1 1 2 2 2 2 Ferroportin1 (FPN1) 2OG-FeII_Oxy_2 PF13532.1 EMR72246.1 - 6.1e-14 52.3 0.0 1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EMR72246.1 - 8.5e-08 32.3 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxidored_q6 PF01058.17 EMR72247.1 - 1.8e-22 79.3 0.1 2.5e-22 78.8 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Methyltransf_16 PF10294.4 EMR72248.1 - 2.3e-18 66.2 0.0 3.2e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EMR72248.1 - 1.4e-06 28.8 0.0 2.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR72248.1 - 0.00014 21.6 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMR72248.1 - 0.00016 21.3 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EMR72248.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EMR72248.1 - 0.0028 16.8 0.0 0.0039 16.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EMR72248.1 - 0.03 13.9 0.1 0.051 13.1 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 EMR72248.1 - 0.03 13.3 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF938 PF06080.7 EMR72248.1 - 0.068 12.7 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 EMR72248.1 - 0.093 12.7 0.1 0.16 12.0 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EMR72249.1 - 1.4e-38 132.5 52.9 4.6e-38 130.8 33.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR72249.1 - 1.3e-13 50.3 27.2 6.5e-11 41.4 11.5 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter Arylsulfotran_2 PF14269.1 EMR72250.1 - 1.5e-69 234.4 2.6 2.1e-69 233.9 1.1 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EMR72250.1 - 3.2e-11 42.4 0.4 4.6e-10 38.5 0.3 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) CVNH PF08881.5 EMR72251.1 - 1.8e-07 31.3 0.1 2.5e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 CVNH domain FMN_dh PF01070.13 EMR72252.1 - 3.8e-28 98.3 0.0 4.1e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Peptidase_M3 PF01432.15 EMR72253.1 - 1.5e-81 274.7 0.1 3.5e-65 220.8 0.0 2.1 1 1 1 2 2 2 2 Peptidase family M3 Peptidase_M91 PF14891.1 EMR72253.1 - 0.032 14.2 0.1 0.06 13.4 0.1 1.4 1 0 0 1 1 1 0 Effector protein MFS_1 PF07690.11 EMR72256.1 - 7.3e-13 47.9 16.6 1.4e-10 40.4 2.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR72256.1 - 0.00012 20.8 0.5 0.00012 20.8 0.3 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter Sulfotransfer_3 PF13469.1 EMR72259.1 - 0.0016 19.3 1.1 0.018 15.9 0.8 2.4 1 1 1 2 2 2 1 Sulfotransferase family Glyco_transf_25 PF01755.12 EMR72260.1 - 7.4e-06 25.7 0.0 0.0061 16.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF3598 PF12204.3 EMR72260.1 - 0.0059 15.8 0.2 0.0099 15.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3598) ApbA PF02558.11 EMR72261.1 - 6.9e-09 35.3 0.0 7e-09 35.3 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EMR72261.1 - 0.0024 17.7 0.3 0.0031 17.3 0.2 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EMR72261.1 - 0.015 15.4 0.1 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 EMR72261.1 - 0.023 15.2 0.1 0.024 15.1 0.0 1.1 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF1580 PF07618.6 EMR72261.1 - 0.033 13.5 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1580) NAD_binding_7 PF13241.1 EMR72261.1 - 0.077 13.2 0.1 0.077 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding IlvN PF07991.7 EMR72261.1 - 0.08 12.3 0.1 0.08 12.3 0.1 1.1 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DAO PF01266.19 EMR72261.1 - 0.11 11.3 0.2 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase adh_short PF00106.20 EMR72263.1 - 5.9e-27 94.6 0.1 8.1e-27 94.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR72263.1 - 8.3e-13 48.6 0.0 1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR72263.1 - 6e-10 39.0 0.1 1.2e-09 38.0 0.1 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EMR72263.1 - 3.1e-05 24.0 0.1 5.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EMR72263.1 - 0.018 14.2 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EMR72263.1 - 0.044 13.5 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3963 PF13124.1 EMR72263.1 - 0.048 13.4 0.5 0.41 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) Epimerase PF01370.16 EMR72263.1 - 0.16 11.3 0.1 0.72 9.2 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ApbA_C PF08546.6 EMR72264.1 - 7.5e-25 87.3 0.0 1e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EMR72264.1 - 1.8e-05 24.1 0.1 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA LMWPc PF01451.16 EMR72265.1 - 1.6e-33 115.9 0.0 1.9e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase RF-1 PF00472.15 EMR72266.1 - 1.9e-33 114.6 0.8 3.5e-33 113.7 0.5 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EMR72266.1 - 1.3e-23 82.8 0.0 2.7e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 PCRF domain PAS_9 PF13426.1 EMR72267.1 - 0.089 13.1 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 PAS domain Tetraspannin PF00335.15 EMR72268.1 - 0.0006 19.1 4.3 0.0006 19.1 3.0 2.0 1 1 1 2 2 2 1 Tetraspanin family DUF2149 PF09919.4 EMR72268.1 - 0.016 15.2 0.7 0.054 13.5 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) DUF2243 PF10002.4 EMR72268.1 - 0.036 13.8 0.6 0.049 13.4 0.4 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2243) DUF4446 PF14584.1 EMR72268.1 - 0.038 13.8 0.5 0.038 13.8 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF2976 PF11190.3 EMR72268.1 - 0.12 11.9 5.3 0.71 9.4 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) DUF898 PF05987.8 EMR72268.1 - 0.12 11.2 13.2 1.3 7.8 9.2 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Neur_chan_memb PF02932.11 EMR72268.1 - 0.15 11.9 4.1 5.4 6.8 0.2 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SUR7 PF06687.7 EMR72268.1 - 0.19 11.2 12.2 0.18 11.3 2.1 2.2 1 1 1 2 2 2 0 SUR7/PalI family ERGIC_N PF13850.1 EMR72268.1 - 1.7 8.7 6.3 0.37 10.8 0.1 2.8 3 1 1 4 4 4 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ETRAMP PF09716.5 EMR72268.1 - 2.4 8.1 6.7 1.5 8.8 0.1 2.9 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) FtsX PF02687.16 EMR72268.1 - 3 7.6 14.0 5.9 6.6 4.7 2.6 1 1 1 2 2 2 0 FtsX-like permease family PIG-P PF08510.7 EMR72268.1 - 4.4 6.9 8.0 17 5.0 5.5 2.1 1 1 0 1 1 1 0 PIG-P DUF3112 PF11309.3 EMR72268.1 - 8.8 6.0 13.9 33 4.2 8.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) TPR_12 PF13424.1 EMR72269.1 - 3.2e-06 26.9 1.5 0.087 12.7 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Clr5 PF14420.1 EMR72269.1 - 3.5e-05 23.6 2.7 3.5e-05 23.6 1.9 2.8 3 0 0 3 3 3 1 Clr5 domain ALO PF04030.9 EMR72269.1 - 0.00015 21.4 0.2 0.00027 20.6 0.1 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Succ_CoA_lig PF13607.1 EMR72270.1 - 0.053 13.1 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain LSM PF01423.17 EMR72272.1 - 1e-17 63.4 0.1 1.3e-17 63.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain dCMP_cyt_deam_1 PF00383.17 EMR72273.1 - 7.1e-19 67.3 0.0 1.7e-18 66.1 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EMR72273.1 - 0.00011 22.0 0.7 0.01 15.7 0.1 2.6 1 1 1 2 2 2 2 Bd3614-like deaminase PX PF00787.19 EMR72275.1 - 6.1e-24 83.9 0.0 7e-24 83.7 0.0 1.0 1 0 0 1 1 1 1 PX domain His_Phos_1 PF00300.17 EMR72276.1 - 7.6e-31 107.3 0.0 8.9e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AA_permease PF00324.16 EMR72278.1 - 3.1e-92 309.4 39.4 3.6e-92 309.2 27.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR72278.1 - 7.1e-25 87.4 42.1 1.8e-24 86.0 29.1 1.6 1 1 0 1 1 1 1 Amino acid permease Zn_clus PF00172.13 EMR72279.1 - 0.069 13.0 8.7 0.13 12.1 6.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 EMR72280.1 - 2.8e-19 69.4 0.0 3.7e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR72280.1 - 2.1e-12 46.4 0.1 1.4e-11 43.8 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EMR72280.1 - 6.2e-10 38.2 0.0 9.2e-10 37.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EMR72280.1 - 3.1e-08 33.8 0.4 6.2e-08 32.8 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMR72280.1 - 2.1e-05 24.4 0.1 4.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EMR72280.1 - 2.7e-05 23.2 0.3 5.3e-05 22.2 0.1 1.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EMR72280.1 - 0.00016 21.7 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase KR PF08659.5 EMR72280.1 - 0.0018 17.9 0.0 0.0033 17.0 0.0 1.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EMR72280.1 - 0.054 12.7 0.1 0.093 11.9 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Mito_carr PF00153.22 EMR72281.1 - 9.1e-71 233.6 0.1 2.1e-22 78.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Saw1 PF11561.3 EMR72282.1 - 0.04 13.3 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Pantoate_ligase PF02569.10 EMR72282.1 - 0.055 12.2 0.1 0.07 11.8 0.0 1.2 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Response_reg PF00072.19 EMR72283.1 - 7.2e-24 83.9 0.0 2.4e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 Response regulator receiver domain Secretin_N PF03958.12 EMR72283.1 - 0.016 15.3 0.1 0.033 14.3 0.1 1.5 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain Methyltransf_23 PF13489.1 EMR72285.1 - 5.4e-18 65.2 0.3 1.1e-17 64.2 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR72285.1 - 8.4e-16 58.2 0.0 1.6e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR72285.1 - 3e-15 56.7 0.0 6.7e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR72285.1 - 3.8e-14 52.5 0.0 8.7e-14 51.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR72285.1 - 6.2e-12 45.8 0.0 1.5e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EMR72285.1 - 9.3e-12 45.1 0.0 2.2e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR72285.1 - 5.3e-07 29.6 0.4 1.4e-06 28.3 0.3 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EMR72285.1 - 1.1e-05 24.7 0.0 1.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EMR72285.1 - 0.00031 20.4 0.0 0.00098 18.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EMR72285.1 - 0.00038 19.6 0.0 0.00067 18.8 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EMR72285.1 - 0.0047 16.3 0.1 0.0093 15.3 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Nop14 PF04147.7 EMR72285.1 - 0.026 12.4 4.4 0.031 12.2 3.0 1.1 1 0 0 1 1 1 0 Nop14-like family Methyltransf_24 PF13578.1 EMR72285.1 - 0.029 15.1 0.0 0.084 13.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Flavi_DEAD PF07652.9 EMR72285.1 - 0.03 14.0 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Flavivirus DEAD domain TPMT PF05724.6 EMR72285.1 - 0.036 13.4 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CDC45 PF02724.9 EMR72285.1 - 0.072 11.1 4.4 0.083 10.9 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RrnaAD PF00398.15 EMR72285.1 - 0.076 12.0 0.0 0.17 10.8 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Paf1 PF03985.8 EMR72285.1 - 0.16 10.7 6.4 0.22 10.2 4.4 1.1 1 0 0 1 1 1 0 Paf1 DUF2457 PF10446.4 EMR72285.1 - 2.1 6.9 12.6 2.8 6.5 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 EMR72285.1 - 2.5 7.6 9.4 4.5 6.7 6.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 EMR72285.1 - 3.2 6.1 9.4 0.36 9.2 3.4 1.6 2 0 0 2 2 2 0 Daxx Family HSP90 PF00183.13 EMR72285.1 - 3.7 5.8 6.9 5.7 5.2 4.8 1.2 1 0 0 1 1 1 0 Hsp90 protein NOA36 PF06524.7 EMR72285.1 - 4.2 6.5 8.0 8.2 5.5 5.5 1.5 1 0 0 1 1 1 0 NOA36 protein E1-E2_ATPase PF00122.15 EMR72286.1 - 2.2e-64 216.6 3.4 2.2e-64 216.6 2.4 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EMR72286.1 - 1.2e-32 114.0 0.1 1.1e-27 97.8 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EMR72286.1 - 8.9e-32 110.0 7.4 8.9e-32 110.0 5.1 2.9 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EMR72286.1 - 8.2e-18 64.1 0.0 1.8e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EMR72286.1 - 1.9e-17 62.4 0.0 4.5e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EMR72286.1 - 1.7e-15 57.7 0.0 4e-15 56.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EMR72286.1 - 0.00018 21.1 0.2 0.00065 19.3 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3439 PF11921.3 EMR72287.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PRP21_like_P PF12230.3 EMR72289.1 - 2.1e-56 190.9 19.5 2.1e-56 190.9 13.5 2.9 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EMR72289.1 - 2.1e-30 104.1 4.3 1.5e-18 66.2 0.1 2.7 2 0 0 2 2 2 2 Surp module p450 PF00067.17 EMR72290.1 - 2.6e-74 250.4 0.0 3.9e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 EMR72290.1 - 7.3e-29 100.7 0.1 1.3e-28 99.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PMT PF02366.13 EMR72292.1 - 2.5e-75 252.9 16.4 5.4e-75 251.9 11.4 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EMR72292.1 - 7.2e-56 188.7 0.1 1.1e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 MIR domain IBR PF01485.16 EMR72293.1 - 0.18 11.6 10.9 0.44 10.4 7.7 1.6 1 1 0 1 1 1 0 IBR domain Meleagrin PF08189.6 EMR72294.1 - 0.0071 15.7 1.9 0.017 14.5 1.3 1.6 1 0 0 1 1 1 1 Meleagrin/Cygnin family UBA_4 PF14555.1 EMR72295.1 - 8.2e-11 41.2 0.0 1.8e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EMR72295.1 - 7.3e-05 22.7 0.0 0.00019 21.4 0.0 1.7 1 0 0 1 1 1 1 UBX domain DUF1816 PF08846.5 EMR72295.1 - 0.038 13.6 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1816) CAF-1_p150 PF11600.3 EMR72295.1 - 8.9 5.6 17.4 0.1 11.9 3.5 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MARVEL PF01284.18 EMR72296.1 - 0.00032 20.5 14.5 0.00083 19.1 5.6 2.1 1 1 1 2 2 2 1 Membrane-associating domain VIT1 PF01988.14 EMR72296.1 - 0.00044 19.8 1.1 0.00044 19.8 0.8 1.5 2 0 0 2 2 2 1 VIT family PQ-loop PF04193.9 EMR72296.1 - 1.5 8.4 0.0 1.5 8.4 0.0 3.5 3 1 0 3 3 3 0 PQ loop repeat Polysacc_synt_3 PF13440.1 EMR72296.1 - 1.7 8.0 17.2 1.1 8.6 9.2 2.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein ABC2_membrane_3 PF12698.2 EMR72296.1 - 2.6 6.9 6.8 3.7 6.4 4.7 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Bax1-I PF01027.15 EMR72296.1 - 4.5 6.8 13.4 0.3 10.6 3.3 2.3 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 FA_desaturase PF00487.19 EMR72296.1 - 6.3 6.1 15.4 5.5 6.3 7.4 2.1 1 1 1 2 2 2 0 Fatty acid desaturase FTR1 PF03239.9 EMR72297.1 - 0.026 13.4 0.1 0.026 13.4 0.0 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family SET PF00856.23 EMR72298.1 - 2.3e-21 76.7 4.0 5.1e-20 72.4 0.6 3.0 2 0 0 2 2 2 2 SET domain HicB PF05534.7 EMR72299.1 - 0.047 13.2 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 HicB family Bot1p PF12298.3 EMR72300.1 - 2.3e-21 76.4 2.4 2.3e-21 76.4 1.6 1.5 1 1 1 2 2 2 1 Eukaryotic mitochondrial regulator protein FAD_binding_3 PF01494.14 EMR72301.1 - 1.9e-20 73.2 2.6 4.3e-13 49.0 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR72301.1 - 2.2e-07 30.0 1.8 2.1e-05 23.5 1.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR72301.1 - 2.1e-05 24.4 1.0 8.1e-05 22.5 0.7 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EMR72301.1 - 3.7e-05 22.6 0.0 0.23 10.2 0.0 2.3 2 1 0 2 2 2 2 Squalene epoxidase Pyr_redox PF00070.22 EMR72301.1 - 8.3e-05 22.9 0.2 0.00022 21.5 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EMR72301.1 - 0.0089 14.7 3.1 0.095 11.3 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase Amino_oxidase PF01593.19 EMR72301.1 - 0.037 13.0 0.6 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EMR72301.1 - 0.048 13.5 0.1 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1934 PF09148.5 EMR72302.1 - 0.026 14.2 0.3 0.037 13.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1934) Ectoine_synth PF06339.7 EMR72302.1 - 0.061 13.2 0.1 1.5 8.7 0.1 2.2 2 0 0 2 2 2 0 Ectoine synthase BAR PF03114.13 EMR72303.1 - 4.4e-13 49.2 0.1 7e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EMR72303.1 - 2.1e-12 46.4 0.1 4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EMR72303.1 - 6.8e-12 44.5 0.0 1.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMR72303.1 - 1.7e-07 30.5 0.0 3.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Urb2 PF10441.4 EMR72304.1 - 7.8e-53 179.3 0.3 3.2e-52 177.3 0.0 1.9 2 0 0 2 2 2 1 Urb2/Npa2 family SR-25 PF10500.4 EMR72304.1 - 0.37 10.2 9.6 0.65 9.4 6.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4419 PF14388.1 EMR72305.1 - 1.2e-05 24.6 0.0 1.5e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) GHMP_kinases_N PF00288.21 EMR72305.1 - 0.055 13.5 0.5 0.073 13.1 0.4 1.4 1 1 0 1 1 1 0 GHMP kinases N terminal domain DUF543 PF04418.7 EMR72306.1 - 2.5e-29 101.0 0.0 2.7e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) p450 PF00067.17 EMR72307.1 - 9.1e-59 199.1 0.0 1.1e-58 198.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_7 PF03441.9 EMR72308.1 - 6.7e-86 287.9 0.0 1e-85 287.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EMR72308.1 - 9.6e-18 64.4 0.0 1.9e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase MFS_1 PF07690.11 EMR72309.1 - 3.5e-23 81.9 11.8 1.6e-11 43.5 1.5 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF2142 PF09913.4 EMR72309.1 - 0.01 14.5 3.9 0.022 13.4 2.7 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF3366 PF11846.3 EMR72309.1 - 0.016 15.1 0.0 0.48 10.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) DUF4064 PF13273.1 EMR72309.1 - 0.067 13.3 5.7 3.7 7.7 0.4 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) EVC2_like PF12297.3 EMR72309.1 - 0.12 10.9 0.0 1.8 7.1 0.0 2.0 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Abhydrolase_3 PF07859.8 EMR72310.1 - 3.7e-34 118.1 0.0 1.2e-23 83.8 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EMR72310.1 - 0.069 11.7 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) DUF605 PF04652.11 EMR72310.1 - 6.8 5.9 8.2 1.9 7.7 3.3 1.7 2 0 0 2 2 2 0 Vta1 like SDA1 PF05285.7 EMR72312.1 - 6.9e-90 301.5 52.3 2.5e-89 299.7 29.1 2.3 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EMR72312.1 - 1.3e-18 67.0 0.1 4.2e-18 65.3 0.1 2.0 1 0 0 1 1 1 1 NUC130/3NT domain Dict-STAT-coil PF09267.5 EMR72312.1 - 0.024 14.8 2.3 0.039 14.1 0.2 2.4 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil DUF2580 PF10824.3 EMR72313.1 - 0.11 12.8 0.6 0.15 12.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) GMC_oxred_C PF05199.8 EMR72314.1 - 9.6e-34 116.7 0.0 2.2e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EMR72314.1 - 1.2e-31 109.9 0.0 3.8e-29 101.7 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 EMR72314.1 - 8.2e-06 24.9 0.0 0.0001 21.2 0.0 2.4 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 EMR72314.1 - 8.8e-05 22.4 0.0 0.00028 20.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR72314.1 - 0.00076 19.4 0.0 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR72314.1 - 0.0012 17.7 0.0 0.01 14.7 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR72314.1 - 0.0014 18.7 0.0 0.8 9.7 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR72314.1 - 0.0095 14.8 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EMR72314.1 - 0.012 14.0 0.0 0.021 13.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EMR72314.1 - 0.013 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EMR72314.1 - 0.028 13.5 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EMR72314.1 - 0.1 11.4 0.1 0.37 9.5 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A HHH PF00633.18 EMR72314.1 - 0.44 10.3 3.2 22 4.9 0.0 3.2 4 0 0 4 4 4 0 Helix-hairpin-helix motif A_deaminase PF00962.17 EMR72316.1 - 1.4e-46 158.9 0.0 1.6e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Pyridoxal_deC PF00282.14 EMR72317.1 - 5.6e-75 252.1 0.0 7.2e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Abhydrolase_6 PF12697.2 EMR72318.1 - 6.5e-27 94.8 0.1 7.6e-27 94.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR72318.1 - 2.4e-13 50.0 0.1 5.3e-13 48.9 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EMR72318.1 - 0.0051 15.7 0.0 0.0099 14.7 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EMR72318.1 - 0.03 13.1 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.3 EMR72318.1 - 0.082 12.7 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 Putative lysophospholipase Abhydrolase_1 PF00561.15 EMR72318.1 - 0.14 11.7 0.0 0.86 9.1 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF3089 PF11288.3 EMR72318.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) FMN_dh PF01070.13 EMR72319.1 - 7.4e-82 275.0 0.2 6.7e-79 265.3 0.1 2.1 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EMR72319.1 - 0.00018 20.5 0.1 0.001 18.1 0.0 1.9 1 1 1 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 EMR72319.1 - 0.0094 14.8 0.2 0.035 13.0 0.1 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 EMR72319.1 - 0.077 11.9 0.1 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Abhydrolase_1 PF00561.15 EMR72320.1 - 9.9e-16 57.9 0.0 1.1e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EMR72320.1 - 2.1e-06 27.8 0.0 2.2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family TauD PF02668.11 EMR72321.1 - 2.6e-16 60.0 0.1 3.5e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family p450 PF00067.17 EMR72322.1 - 1.1e-82 278.0 0.0 1.3e-82 277.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_2 PF00703.16 EMR72324.1 - 1.9e-06 28.2 0.3 1.5e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EMR72324.1 - 7.5e-06 25.0 0.0 1.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 EMR72324.1 - 0.0001 21.8 0.1 0.00033 20.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF3533 PF12051.3 EMR72325.1 - 5.5e-98 328.2 15.3 8.1e-98 327.6 10.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.7 EMR72325.1 - 1.2 8.7 0.0 1.2 8.7 0.0 3.7 4 1 0 4 4 4 0 CDR ABC transporter EthD PF07110.6 EMR72327.1 - 2.5e-05 25.0 0.0 0.00011 23.0 0.0 2.0 1 1 0 1 1 1 1 EthD domain AA_permease_2 PF13520.1 EMR72328.1 - 4.7e-55 186.8 34.7 2e-41 141.9 12.2 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EMR72328.1 - 3.8e-16 58.4 29.2 1.5e-11 43.3 20.2 2.2 1 1 0 1 1 1 1 Amino acid permease K1 PF02960.9 EMR72328.1 - 0.058 13.4 0.5 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 K1 glycoprotein GvpH PF05455.6 EMR72329.1 - 0.041 13.5 2.3 0.75 9.3 0.0 2.9 3 0 0 3 3 3 0 GvpH Lin-8 PF03353.10 EMR72329.1 - 0.16 11.2 4.5 0.19 10.9 3.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MCPVI PF02993.9 EMR72329.1 - 0.27 11.3 4.0 0.33 11.0 2.8 1.1 1 0 0 1 1 1 0 Minor capsid protein VI DUF4519 PF15012.1 EMR72329.1 - 4.4 7.2 6.3 1.4 8.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) HET PF06985.6 EMR72330.1 - 1.7e-35 122.1 1.4 2e-35 121.9 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Peptidase_C12 PF01088.16 EMR72331.1 - 9.7e-53 178.5 0.0 1.1e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Cbl_N3 PF02762.9 EMR72331.1 - 0.045 13.3 0.0 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain AICARFT_IMPCHas PF01808.13 EMR72332.1 - 1.9e-112 375.4 0.0 2.4e-112 375.1 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EMR72332.1 - 8.4e-24 83.3 0.0 1.5e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain Clr5 PF14420.1 EMR72333.1 - 1.4e-19 69.7 2.4 2.3e-19 69.0 1.7 1.4 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 EMR72333.1 - 4e-09 36.2 2.8 3.5e-07 30.0 0.6 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EMR72333.1 - 1e-05 25.2 9.4 0.00061 19.6 0.9 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMR72333.1 - 0.0081 16.4 3.4 3.2 8.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 EMR72333.1 - 0.018 15.1 0.0 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EMR72333.1 - 0.019 14.6 0.1 0.21 11.2 0.1 2.5 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 EMR72333.1 - 0.039 13.8 2.7 12 6.1 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EMR72333.1 - 0.07 13.8 10.1 3 8.7 1.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EMR72333.1 - 0.3 11.8 10.1 40 5.0 0.0 3.5 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EMR72333.1 - 2.6 8.7 0.0 2.6 8.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SKI PF01202.17 EMR72334.1 - 4e-12 46.2 0.0 5.4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 EMR72334.1 - 1.6e-11 45.0 0.0 2.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EMR72334.1 - 2.7e-11 43.5 0.0 3.3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMR72334.1 - 8.2e-09 35.8 0.1 4.8e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EMR72334.1 - 6.8e-05 23.0 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EMR72334.1 - 0.00013 22.1 0.0 0.00023 21.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EMR72334.1 - 0.00034 19.4 0.0 0.00047 18.9 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 EMR72334.1 - 0.00035 20.2 0.0 0.00066 19.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.1 EMR72334.1 - 0.0006 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR72334.1 - 0.0007 19.6 0.0 0.0014 18.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EMR72334.1 - 0.0018 18.1 0.0 0.0034 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EMR72334.1 - 0.002 17.8 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.1 EMR72334.1 - 0.0029 17.5 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 Cytidylate kinase-like family RNA_helicase PF00910.17 EMR72334.1 - 0.0031 17.6 0.0 0.0059 16.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 EMR72334.1 - 0.0035 17.0 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EMR72334.1 - 0.012 14.7 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EMR72334.1 - 0.014 14.2 0.0 0.098 11.5 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein APS_kinase PF01583.15 EMR72334.1 - 0.021 14.4 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase PRK PF00485.13 EMR72334.1 - 0.036 13.6 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 EMR72334.1 - 0.043 12.9 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EMR72334.1 - 0.051 12.5 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 EMR72334.1 - 0.062 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 EMR72334.1 - 0.064 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 EMR72334.1 - 0.064 13.5 0.0 0.2 11.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter ADK PF00406.17 EMR72334.1 - 0.066 13.0 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 Adenylate kinase NTPase_1 PF03266.10 EMR72334.1 - 0.067 12.9 0.0 0.16 11.6 0.0 1.5 2 0 0 2 2 1 0 NTPase CobU PF02283.11 EMR72334.1 - 0.081 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Viral_helicase1 PF01443.13 EMR72334.1 - 0.086 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.7 EMR72334.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EMR72334.1 - 0.14 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.1 EMR72334.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 DNA polymerase III, delta subunit KaiC PF06745.8 EMR72334.1 - 0.16 11.0 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 KaiC zf-MYND PF01753.13 EMR72336.1 - 1.5e-09 37.6 17.4 2.3e-09 36.9 12.0 1.3 1 0 0 1 1 1 1 MYND finger SUN PF03856.8 EMR72337.1 - 1.3e-84 283.3 10.8 1.8e-84 282.9 7.5 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) TMEM171 PF15471.1 EMR72337.1 - 1.8 7.2 6.1 2.8 6.6 4.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 EF1_GNE PF00736.14 EMR72338.1 - 5.1e-32 109.4 3.8 9.1e-32 108.6 2.6 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EMR72338.1 - 8.2e-15 54.6 6.4 8.2e-15 54.6 4.4 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EMR72338.1 - 5.7e-05 23.5 0.0 0.00015 22.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EMR72338.1 - 0.0015 18.4 0.2 0.0057 16.6 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DNA_pol3_a_NII PF11490.3 EMR72338.1 - 2.6 7.7 5.1 1.2 8.7 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II AAA_2 PF07724.9 EMR72339.1 - 2.8e-43 147.7 0.0 1.7e-42 145.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EMR72339.1 - 1.2e-25 89.1 0.3 1.2e-25 89.1 0.2 2.1 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EMR72339.1 - 3.3e-19 69.4 0.0 2.7e-10 40.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMR72339.1 - 9.8e-13 48.0 0.1 9.3e-09 35.1 0.0 3.2 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EMR72339.1 - 1.4e-11 44.7 10.8 0.0011 18.9 0.0 5.1 3 2 2 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 EMR72339.1 - 3.1e-10 40.3 1.8 0.0003 20.9 0.0 3.4 3 2 1 4 4 2 2 AAA domain Sigma54_activat PF00158.21 EMR72339.1 - 2.4e-07 30.4 0.2 0.00018 21.0 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EMR72339.1 - 4.1e-06 26.7 0.0 0.063 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EMR72339.1 - 7.4e-06 25.7 0.1 0.18 11.4 0.0 2.8 2 1 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 EMR72339.1 - 9.3e-06 26.4 5.9 0.0069 17.1 0.0 4.4 5 1 0 5 5 4 1 AAA domain AAA_18 PF13238.1 EMR72339.1 - 4.6e-05 23.7 5.8 0.05 13.9 0.0 3.8 4 0 0 4 4 3 2 AAA domain Arch_ATPase PF01637.13 EMR72339.1 - 5e-05 23.1 7.0 0.2 11.3 0.2 4.5 3 2 0 3 3 2 1 Archaeal ATPase MobB PF03205.9 EMR72339.1 - 0.00016 21.4 0.2 0.085 12.5 0.0 3.3 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EMR72339.1 - 0.00026 20.4 0.0 0.44 9.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EMR72339.1 - 0.00027 20.6 0.0 0.052 13.3 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 EMR72339.1 - 0.0018 18.6 0.8 0.87 9.8 0.0 3.4 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.17 EMR72339.1 - 0.002 18.3 0.0 0.32 11.1 0.0 2.9 2 1 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 EMR72339.1 - 0.0056 16.6 2.3 5.8 6.8 0.0 4.0 4 0 0 4 4 4 0 AAA domain SRP54 PF00448.17 EMR72339.1 - 0.006 16.0 0.0 0.2 11.0 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Mg_chelatase PF01078.16 EMR72339.1 - 0.0061 15.7 0.2 2.1 7.4 0.0 3.2 3 1 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EMR72339.1 - 0.0065 15.8 0.5 4.6 6.5 0.0 3.3 2 2 1 3 3 3 0 AAA domain AAA_10 PF12846.2 EMR72339.1 - 0.0071 15.8 0.1 0.35 10.2 0.0 3.4 3 2 0 3 3 2 1 AAA-like domain DUF258 PF03193.11 EMR72339.1 - 0.01 15.0 0.0 2.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EMR72339.1 - 0.011 15.5 0.0 4.7 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EMR72339.1 - 0.012 15.2 0.1 1.1 8.7 0.0 3.6 3 0 0 3 3 3 0 AAA domain PhoH PF02562.11 EMR72339.1 - 0.012 14.8 0.0 0.37 9.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.10 EMR72339.1 - 0.026 14.3 2.2 4.6 7.0 0.0 3.5 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit IncA PF04156.9 EMR72339.1 - 0.033 13.7 9.3 0.077 12.5 6.5 1.6 1 0 0 1 1 1 0 IncA protein AAA_24 PF13479.1 EMR72339.1 - 0.037 13.5 0.0 0.84 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EMR72339.1 - 0.039 12.8 0.4 1.6 7.6 0.2 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF815) Miro PF08477.8 EMR72339.1 - 0.054 13.9 0.0 2.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 EMR72339.1 - 0.071 12.6 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EMR72339.1 - 0.074 12.5 0.0 3.8 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EMR72339.1 - 0.078 12.5 0.0 0.5 9.8 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 EMR72339.1 - 0.081 12.5 0.0 14 5.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Atg14 PF10186.4 EMR72339.1 - 0.15 10.9 6.8 0.3 9.9 4.7 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_15 PF13175.1 EMR72339.1 - 0.38 9.7 0.0 0.38 9.7 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain APG6 PF04111.7 EMR72339.1 - 0.45 9.4 7.8 0.76 8.7 5.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1640 PF07798.6 EMR72339.1 - 0.58 10.1 6.8 1.2 9.1 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Bacillus_HBL PF05791.6 EMR72339.1 - 0.64 9.3 3.6 0.67 9.2 1.5 1.7 2 0 0 2 2 1 0 Bacillus haemolytic enterotoxin (HBL) V_ATPase_I PF01496.14 EMR72339.1 - 0.73 7.6 3.8 1 7.1 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OEP PF02321.13 EMR72339.1 - 0.83 9.2 10.4 1.9 8.0 7.2 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein Mnd1 PF03962.10 EMR72339.1 - 1.7 8.2 11.9 3.1 7.4 8.2 1.4 1 0 0 1 1 1 0 Mnd1 family DUF2968 PF11180.3 EMR72339.1 - 1.8 7.8 9.6 3.7 6.8 6.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) TBPIP PF07106.8 EMR72339.1 - 2.8 7.4 12.3 1.4 8.4 6.6 1.8 2 0 0 2 2 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 EMR72339.1 - 6 6.9 15.8 1.4 8.9 7.4 2.7 3 0 0 3 3 1 0 Seryl-tRNA synthetase N-terminal domain DUF904 PF06005.7 EMR72339.1 - 8.4 6.7 15.0 0.34 11.2 4.1 2.9 2 1 1 3 3 2 0 Protein of unknown function (DUF904) OmpH PF03938.9 EMR72339.1 - 9.7 6.1 11.0 30 4.4 7.6 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) cNMP_binding PF00027.24 EMR72340.1 - 3.4e-18 65.2 0.0 4.3e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ribosomal_S19 PF00203.16 EMR72341.1 - 3.8e-34 116.1 0.3 6e-34 115.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Peptidase_M49 PF03571.10 EMR72342.1 - 8.4e-219 727.2 0.0 1e-218 726.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 DUF2263 PF10021.4 EMR72344.1 - 1.3e-17 64.1 0.0 5.8e-17 62.0 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 EMR72344.1 - 0.0017 18.2 0.0 0.45 10.4 0.0 2.9 2 1 0 3 3 3 2 Macro domain DUF3530 PF12048.3 EMR72344.1 - 0.0097 14.9 0.8 1.8 7.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3530) Sporozoite_P67 PF05642.6 EMR72344.1 - 5.4 4.7 9.7 0.05 11.4 0.7 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Cmyb_C PF09316.5 EMR72345.1 - 0.033 13.8 1.2 0.033 13.8 0.8 1.8 3 0 0 3 3 3 0 C-myb, C-terminal GCV_T PF01571.16 EMR72346.1 - 4.6e-64 215.6 0.0 6e-64 215.2 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EMR72346.1 - 6.1e-25 87.0 1.1 1.3e-24 86.0 0.8 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain EMP24_GP25L PF01105.19 EMR72347.1 - 1.4e-44 151.9 0.1 1.6e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dioxygenase_C PF00775.16 EMR72347.1 - 0.016 14.4 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Dioxygenase DUF3659 PF12396.3 EMR72350.1 - 0.00089 18.8 0.3 0.003 17.1 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3659) BLVR PF06375.6 EMR72350.1 - 0.11 12.3 5.3 0.18 11.6 3.7 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) IFT43 PF15305.1 EMR72350.1 - 0.67 9.9 4.6 0.11 12.5 0.8 1.4 2 0 0 2 2 2 0 Intraflagellar transport protein 43 DUF3628 PF12300.3 EMR72350.1 - 5.1 7.1 11.1 7.8 6.4 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Dsh_C PF12316.3 EMR72350.1 - 8.8 6.3 9.3 11 6.0 6.4 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Proteasom_Rpn13 PF04683.8 EMR72351.1 - 5.1e-28 96.9 0.0 8e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RRM_1 PF00076.17 EMR72352.1 - 3e-12 45.9 0.0 5.4e-05 22.7 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR72352.1 - 5.4e-11 42.3 0.0 0.0002 21.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR72352.1 - 0.00059 19.6 0.0 0.0041 16.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 3-HAO PF06052.7 EMR72353.1 - 1.3e-64 216.1 0.0 1.5e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EMR72353.1 - 6.9e-07 28.6 0.0 1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EMR72353.1 - 6.3e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DZR PF12773.2 EMR72353.1 - 0.0019 17.9 2.6 0.0037 17.0 1.8 1.4 1 0 0 1 1 1 1 Double zinc ribbon ADK_lid PF05191.9 EMR72353.1 - 0.0027 17.3 0.1 0.011 15.4 0.1 2.0 1 0 0 1 1 1 1 Adenylate kinase, active site lid Cupin_1 PF00190.17 EMR72353.1 - 0.0051 16.2 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 Cupin zf-ribbon_3 PF13248.1 EMR72353.1 - 0.0086 15.2 1.1 0.85 8.9 0.0 2.4 2 0 0 2 2 2 1 zinc-ribbon domain C1_1 PF00130.17 EMR72353.1 - 0.012 15.3 1.1 0.37 10.5 0.1 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TF_Zn_Ribbon PF08271.7 EMR72353.1 - 0.021 14.1 0.2 2.9 7.2 0.0 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding FYVE PF01363.16 EMR72353.1 - 0.03 14.2 1.3 0.052 13.4 0.9 1.4 1 0 0 1 1 1 0 FYVE zinc finger ARD PF03079.9 EMR72353.1 - 0.08 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Nudix_N_2 PF14803.1 EMR72353.1 - 0.16 11.6 3.1 0.5 10.0 0.1 2.5 2 1 1 3 3 3 0 Nudix N-terminal zf-dskA_traR PF01258.12 EMR72353.1 - 1.1 9.0 5.3 13 5.6 0.1 2.5 2 1 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger C1_3 PF07649.7 EMR72353.1 - 6.1 6.9 6.1 0.53 10.3 0.7 1.9 2 0 0 2 2 2 0 C1-like domain Arf PF00025.16 EMR72354.1 - 1.4e-79 265.3 0.2 1.7e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EMR72354.1 - 1.6e-14 53.5 0.0 2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EMR72354.1 - 2.4e-13 49.8 0.0 2.6e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EMR72354.1 - 2.2e-12 46.3 1.7 2.3e-09 36.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EMR72354.1 - 3.7e-11 42.6 0.0 4.3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EMR72354.1 - 1.2e-08 35.4 0.0 1.8e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EMR72354.1 - 2.5e-06 27.4 0.0 3.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EMR72354.1 - 0.0087 15.1 0.6 0.018 14.0 0.4 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EMR72354.1 - 0.012 15.0 0.2 0.093 12.1 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EMR72354.1 - 0.04 13.7 0.2 0.097 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain Ribosomal_L6e PF01159.14 EMR72355.1 - 3.6e-37 126.8 0.3 6.4e-37 126.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e DUF2744 PF10910.3 EMR72355.1 - 0.075 12.8 1.1 0.15 11.8 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2744) Sld5 PF05916.6 EMR72356.1 - 4e-13 49.5 0.0 5.4e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein DUF3405 PF11885.3 EMR72357.1 - 2.9e-208 692.1 3.0 3.5e-208 691.8 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Polysacc_deac_1 PF01522.16 EMR72359.1 - 1.3e-28 99.1 0.0 2.4e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EMR72359.1 - 9.5e-17 60.6 40.3 1.8e-08 34.2 15.2 2.6 2 0 0 2 2 2 2 Chitin recognition protein CENP-B_dimeris PF09026.5 EMR72359.1 - 0.03 14.5 6.7 0.051 13.8 4.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EMR72359.1 - 0.32 10.4 4.2 0.52 9.8 2.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 EMR72359.1 - 3.7 6.1 8.9 6 5.4 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase PF00069.20 EMR72360.1 - 1.1e-47 162.3 0.2 1.8e-47 161.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR72360.1 - 2.2e-26 92.4 0.0 3.3e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EMR72360.1 - 4.6e-08 33.0 0.2 1.2e-07 31.7 0.2 1.8 1 0 0 1 1 1 1 FHA domain YrbL-PhoP_reg PF10707.4 EMR72360.1 - 0.038 13.3 0.0 0.088 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1413 PF07205.6 EMR72361.1 - 0.035 13.6 0.1 0.24 10.9 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1413) SPT2 PF08243.6 EMR72362.1 - 5.3e-09 36.4 22.5 9.5e-07 29.1 15.6 2.3 1 1 0 1 1 1 1 SPT2 chromatin protein Ribosomal_S8e PF01201.17 EMR72363.1 - 5.7e-36 123.5 6.5 2.6e-35 121.4 4.5 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e HPD PF05044.7 EMR72363.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Homeo-prospero domain DUF2390 PF09523.5 EMR72363.1 - 8.4 6.6 7.4 16 5.7 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Ammonium_transp PF00909.16 EMR72364.1 - 2.6e-102 342.3 20.4 3.1e-102 342.0 14.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4229 PF14012.1 EMR72364.1 - 0.51 10.2 7.7 1.4 8.8 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF3185 PF11381.3 EMR72364.1 - 0.91 9.3 7.5 13 5.6 0.3 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) WH2 PF02205.15 EMR72366.1 - 9.4e-10 37.7 3.1 3.8e-09 35.8 0.5 2.6 2 0 0 2 2 2 1 WH2 motif Gly-zipper_YMGG PF13441.1 EMR72366.1 - 4.3 6.9 13.2 14 5.3 9.1 1.9 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF1989 PF09347.5 EMR72367.1 - 1.8e-55 186.8 0.0 2.3e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) RNA_pol_Rbc25 PF08292.7 EMR72369.1 - 2e-32 111.9 1.0 2.7e-32 111.5 0.3 1.5 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EMR72369.1 - 5.6e-16 58.4 0.0 9.1e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EMR72369.1 - 0.00049 20.1 0.0 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 S1 RNA binding domain Coiled-coil_56 PF09813.4 EMR72370.1 - 0.0011 18.8 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF106 PF01956.11 EMR72372.1 - 1.3e-55 187.5 1.3 1.7e-55 187.0 0.9 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 PKI PF02827.11 EMR72373.1 - 0.063 13.3 1.4 0.12 12.4 1.0 1.5 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor F-box PF00646.28 EMR72374.1 - 0.00032 20.2 0.0 0.00082 18.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EMR72374.1 - 0.022 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.20 EMR72375.1 - 1.9e-45 155.0 0.0 3.5e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR72375.1 - 6.1e-18 64.8 0.0 5.7e-17 61.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EMR72375.1 - 0.00014 21.6 0.6 0.51 10.0 0.1 3.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family PsaA_PsaB PF00223.14 EMR72375.1 - 0.015 13.4 0.0 0.022 12.8 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Kinase-like PF14531.1 EMR72375.1 - 0.028 13.3 0.1 0.51 9.2 0.0 2.3 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 EMR72375.1 - 0.064 12.5 0.1 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family F-box-like PF12937.2 EMR72376.1 - 2.5e-05 23.9 0.1 8.3e-05 22.2 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMR72376.1 - 0.0017 17.9 0.0 0.0048 16.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain Zip PF02535.17 EMR72376.1 - 0.0081 15.2 0.3 0.011 14.7 0.2 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter SPC25 PF06703.6 EMR72377.1 - 5.8e-51 172.2 0.0 6.9e-51 172.0 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) RPN7 PF10602.4 EMR72377.1 - 0.12 11.7 0.1 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 26S proteasome subunit RPN7 DUF2229 PF09989.4 EMR72378.1 - 2.4 7.5 11.0 0.21 11.0 1.2 2.2 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) P4Ha_N PF08336.6 EMR72378.1 - 6.6 6.5 13.8 0.19 11.5 1.4 2.7 2 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Tubulin PF00091.20 EMR72379.1 - 1.3e-62 211.4 0.0 1.8e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EMR72379.1 - 8.3e-44 148.6 0.0 1.3e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EMR72379.1 - 7.4e-05 22.2 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain MMS19_C PF12460.3 EMR72380.1 - 0.077 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal WW PF00397.21 EMR72381.1 - 2.5e-09 36.8 5.1 5.7e-09 35.6 3.5 1.7 1 0 0 1 1 1 1 WW domain DUF4375 PF14300.1 EMR72381.1 - 5.5 7.0 8.5 26 4.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Sds3 PF08598.6 EMR72382.1 - 1.6e-27 96.4 5.1 1.6e-27 96.4 3.6 3.2 2 2 0 2 2 2 1 Sds3-like TMEM247 PF15444.1 EMR72382.1 - 7.1 6.3 8.8 3.9 7.2 4.4 1.8 1 1 0 1 1 1 0 Transmembrane protein 247 THF_DHG_CYH PF00763.18 EMR72383.1 - 1.9e-19 69.8 0.1 2.7e-19 69.3 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EMR72383.1 - 2.5e-12 46.1 0.1 1.3e-08 34.1 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 EMR72383.1 - 0.00058 18.8 0.1 0.00081 18.3 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle NUFIP1 PF10453.4 EMR72384.1 - 5.6e-07 28.9 4.0 5.6e-07 28.9 2.8 2.6 2 1 1 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EMR72384.1 - 0.14 11.8 5.9 0.23 11.2 4.1 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UPF0182 PF03699.8 EMR72384.1 - 0.86 7.4 1.8 1.2 7.0 1.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) MFS_1 PF07690.11 EMR72385.1 - 4.3e-28 98.0 30.2 4.3e-28 98.0 20.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CHORD PF04968.7 EMR72386.1 - 8.9e-52 173.2 18.3 1.5e-26 92.3 2.8 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.11 EMR72386.1 - 1.2e-11 45.0 0.0 2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 CS domain Ribosomal_60s PF00428.14 EMR72387.1 - 2e-27 95.4 13.1 2.3e-27 95.2 9.1 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein RibD_C PF01872.12 EMR72387.1 - 0.092 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain Transp_cyt_pur PF02133.10 EMR72388.1 - 5.8e-121 404.1 30.2 5.3e-98 328.4 10.5 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin PARP PF00644.15 EMR72389.1 - 2.9e-62 209.7 0.0 6.8e-62 208.5 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EMR72389.1 - 9.5e-41 138.5 1.0 1.5e-40 137.9 0.7 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EMR72389.1 - 9.9e-22 76.6 0.1 2.7e-21 75.3 0.1 1.8 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 EMR72389.1 - 6.2e-10 39.0 0.0 1.4e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EMR72389.1 - 3.2e-07 30.0 0.1 9.3e-07 28.6 0.1 1.8 1 0 0 1 1 1 1 twin BRCT domain HpcH_HpaI PF03328.9 EMR72390.1 - 1.9e-26 92.3 0.0 2.1e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Cys_Met_Meta_PP PF01053.15 EMR72391.1 - 4e-138 459.8 0.1 4.6e-138 459.6 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EMR72391.1 - 8.5e-08 31.3 0.5 2.2e-07 29.9 0.3 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EMR72391.1 - 1.5e-06 27.4 0.1 2.2e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EMR72391.1 - 1.1e-05 24.6 0.6 2e-05 23.7 0.4 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EMR72391.1 - 6.1e-05 22.3 0.7 0.00012 21.3 0.5 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase RRM_1 PF00076.17 EMR72392.1 - 1e-12 47.4 0.2 1e-08 34.6 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR72392.1 - 8.7e-11 41.5 0.0 0.0001 22.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR72392.1 - 1.3e-09 37.9 0.0 1.5e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 EMR72392.1 - 0.084 11.3 20.7 0.12 10.7 14.4 1.2 1 0 0 1 1 1 0 Daxx Family KH_1 PF00013.24 EMR72393.1 - 3.9e-38 128.8 12.4 3.4e-14 52.2 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EMR72393.1 - 1.5e-29 101.1 13.5 7.9e-11 41.3 0.5 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EMR72393.1 - 1.3e-09 37.4 9.7 0.0083 15.6 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EMR72393.1 - 1.8e-08 33.8 3.9 0.035 13.7 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EMR72393.1 - 0.00034 20.3 4.8 0.76 9.6 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EMR72393.1 - 0.0034 16.8 0.5 0.52 9.7 0.0 3.1 3 0 0 3 3 3 1 dUTPase UAA PF08449.6 EMR72394.1 - 1.8e-69 234.0 0.7 4.6e-69 232.6 0.5 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EMR72394.1 - 8.2e-10 38.7 22.6 1.8e-06 27.9 3.8 3.5 4 0 0 4 4 4 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EMR72394.1 - 8.4e-06 25.0 1.2 0.0014 17.7 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EMR72394.1 - 1.8e-05 24.9 21.7 0.00017 21.7 4.9 3.0 3 1 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EMR72394.1 - 0.0006 19.4 4.4 0.0006 19.4 3.0 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family Myb_DNA-binding PF00249.26 EMR72395.1 - 2.3e-12 46.7 3.9 8e-10 38.6 0.1 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMR72395.1 - 4.2e-08 33.1 4.8 2.3e-05 24.3 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain GFO_IDH_MocA PF01408.17 EMR72396.1 - 1.3e-20 74.0 0.1 2.3e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EMR72396.1 - 0.00059 20.2 0.1 0.0011 19.3 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain SRX PF09201.5 EMR72396.1 - 0.036 13.7 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 SRX DXP_reductoisom PF02670.11 EMR72396.1 - 0.038 14.5 0.0 0.074 13.5 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase OpuAC PF04069.7 EMR72396.1 - 0.058 12.7 0.0 1.4 8.2 0.0 2.7 2 1 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system Aldo_ket_red PF00248.16 EMR72397.1 - 7.4e-18 64.3 0.0 1.7e-17 63.1 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family CAP_GLY PF01302.20 EMR72398.1 - 1.4e-22 79.1 2.5 2.2e-22 78.4 1.7 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EMR72398.1 - 6.6e-18 64.7 0.0 9.6e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain Methyltransf_12 PF08242.7 EMR72399.1 - 0.00013 22.3 0.4 0.11 12.9 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EMR72399.1 - 0.00047 19.9 0.0 0.0014 18.3 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR72399.1 - 0.0017 17.9 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EMR72399.1 - 0.0026 18.3 0.2 0.0043 17.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR72399.1 - 0.026 15.0 0.0 0.12 12.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain TRI12 PF06609.8 EMR72400.1 - 2.8e-08 32.4 2.1 3.5e-08 32.1 1.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gly-zipper_OmpA PF13436.1 EMR72400.1 - 3.5 7.2 6.9 8.1 6.1 4.8 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain CorA PF01544.13 EMR72403.1 - 9.4e-06 24.8 2.7 6.4e-05 22.1 0.0 3.2 4 0 0 4 4 4 1 CorA-like Mg2+ transporter protein DUF755 PF05501.6 EMR72403.1 - 0.03 14.3 0.8 5.2 7.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Uds1 PF15456.1 EMR72403.1 - 1.7 8.6 8.5 0.13 12.2 1.1 2.4 2 0 0 2 2 2 0 Up-regulated During Septation Pkinase PF00069.20 EMR72406.1 - 2.3e-68 230.1 0.0 9e-68 228.2 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR72406.1 - 3.1e-48 164.0 0.0 5.7e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EMR72406.1 - 3.1e-29 100.9 0.3 1.2e-28 99.0 0.0 2.0 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 EMR72406.1 - 1.1e-17 63.5 0.1 2.9e-17 62.2 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EMR72406.1 - 4.8e-16 58.6 0.0 8.7e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EMR72406.1 - 3.7e-13 49.7 0.0 7.2e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 EMR72406.1 - 8.4e-07 28.2 0.0 0.00055 18.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.11 EMR72406.1 - 0.00019 21.0 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ste50p-SAM PF09235.5 EMR72406.1 - 0.087 12.8 0.3 0.23 11.5 0.2 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif FAD_binding_3 PF01494.14 EMR72407.1 - 4.4e-17 62.1 3.4 5e-15 55.3 2.4 2.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EMR72407.1 - 2.5e-05 24.1 0.0 5.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EMR72407.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR72407.1 - 0.016 15.6 0.0 0.045 14.1 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR72407.1 - 0.027 13.3 0.0 0.077 11.8 0.0 1.6 1 1 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EMR72407.1 - 0.094 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain F-box PF00646.28 EMR72408.1 - 0.94 9.2 5.8 5.2 6.8 0.2 3.0 3 0 0 3 3 3 0 F-box domain DNA_ligase_A_N PF04675.9 EMR72409.1 - 3e-53 180.2 0.0 6.2e-53 179.2 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 EMR72409.1 - 1.6e-49 168.0 2.0 4e-38 130.8 0.5 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 EMR72409.1 - 4.1e-29 100.8 0.0 2.1e-28 98.5 0.0 2.3 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region ECH PF00378.15 EMR72410.1 - 1.5e-67 227.3 0.2 1.7e-67 227.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SH3_9 PF14604.1 EMR72411.1 - 1.6e-06 27.5 0.2 1.6e-06 27.5 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EMR72411.1 - 7.4e-05 22.0 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EMR72411.1 - 0.0044 16.4 0.8 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain zf-UBR PF02207.15 EMR72411.1 - 0.24 11.1 25.8 0.33 10.6 0.2 3.5 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) HypA PF01155.14 EMR72411.1 - 0.31 10.7 6.5 6 6.5 0.2 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Ribosomal_L23eN PF03939.8 EMR72412.1 - 1.8e-19 69.4 7.7 1.8e-19 69.4 5.3 2.2 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EMR72412.1 - 4.9e-17 61.6 1.9 4.9e-17 61.6 1.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 ASL_C PF08328.6 EMR72412.1 - 0.073 12.9 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal TusA PF01206.12 EMR72412.1 - 0.1 12.2 0.1 0.55 9.8 0.1 2.0 2 0 0 2 2 2 0 Sulfurtransferase TusA ABC_tran PF00005.22 EMR72413.1 - 3.8e-33 114.6 0.0 5.8e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMR72413.1 - 3.3e-05 24.0 0.0 0.0022 17.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EMR72413.1 - 0.0028 16.7 0.0 0.0055 15.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF258 PF03193.11 EMR72413.1 - 0.0031 16.7 0.0 0.0054 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EMR72413.1 - 0.0061 15.9 0.2 0.087 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EMR72413.1 - 0.01 15.3 0.5 0.022 14.2 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EMR72413.1 - 0.011 16.6 0.0 0.03 15.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 EMR72413.1 - 0.024 14.2 0.3 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EMR72413.1 - 0.047 13.6 0.2 0.12 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.1 EMR72413.1 - 0.053 13.4 3.2 0.12 12.2 0.2 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_membrane PF00664.18 EMR72413.1 - 0.057 12.8 1.0 0.093 12.1 0.7 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region AAA_18 PF13238.1 EMR72413.1 - 0.058 13.7 0.4 0.45 10.8 0.2 2.5 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EMR72413.1 - 0.075 13.3 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EMR72413.1 - 0.076 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) APS_kinase PF01583.15 EMR72413.1 - 0.16 11.5 0.7 0.45 10.1 0.1 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase HET PF06985.6 EMR72414.1 - 7.9e-20 71.4 0.0 1.4e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Na_Ca_ex PF01699.19 EMR72416.1 - 1.7e-35 121.6 24.0 5.2e-20 71.4 3.8 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EMR72416.1 - 1.3e-13 51.1 12.4 1.3e-13 51.1 8.6 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF307) Daxx PF03344.10 EMR72416.1 - 1.8 6.9 12.0 3.4 6.0 8.3 1.3 1 0 0 1 1 1 0 Daxx Family Y_phosphatase PF00102.22 EMR72417.1 - 4.6e-62 209.4 0.0 1.3e-34 119.5 0.0 3.1 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EMR72417.1 - 0.0022 18.2 0.0 0.0075 16.5 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EMR72417.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain OB_NTP_bind PF07717.11 EMR72418.1 - 8.9e-27 93.1 0.3 2.4e-26 91.8 0.1 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EMR72418.1 - 3.5e-22 78.3 0.0 8.3e-22 77.1 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EMR72418.1 - 5.9e-10 38.8 0.0 1.4e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMR72418.1 - 2.2e-08 33.7 0.1 5.5e-08 32.4 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EMR72418.1 - 3.5e-07 30.4 0.0 9.8e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EMR72418.1 - 0.00011 21.6 0.0 0.00031 20.2 0.0 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 EMR72418.1 - 0.0037 16.2 0.0 0.0072 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EMR72418.1 - 0.005 16.6 0.1 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain Pox_I1 PF03289.8 EMR72418.1 - 0.0054 15.6 0.4 0.01 14.7 0.3 1.4 1 0 0 1 1 1 1 Poxvirus protein I1 ResIII PF04851.10 EMR72418.1 - 0.0059 16.4 0.0 2.1 8.1 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_23 PF13476.1 EMR72418.1 - 0.014 15.7 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF443 PF04276.7 EMR72418.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Response_reg PF00072.19 EMR72418.1 - 0.15 12.0 0.7 0.51 10.3 0.1 2.1 2 0 0 2 2 2 0 Response regulator receiver domain Amidase PF01425.16 EMR72419.1 - 1.7e-60 205.1 0.1 2.3e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Amidase COesterase PF00135.23 EMR72420.1 - 1.3e-87 294.7 0.0 3.2e-79 267.0 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR72420.1 - 1.8e-11 44.0 0.0 2.9e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR72420.1 - 0.021 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family APC10 PF03256.11 EMR72421.1 - 2.3e-49 167.6 0.0 3.2e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) RRN3 PF05327.6 EMR72421.1 - 1.4 6.9 7.2 7 4.6 3.1 2.0 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 EMR72421.1 - 6.6 5.0 12.5 8.5 4.7 8.7 1.1 1 0 0 1 1 1 0 Daxx Family Ras PF00071.17 EMR72422.1 - 2.2e-21 75.9 0.0 3.5e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Ras family EcsC PF12787.2 EMR72422.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 EcsC protein family NPV_P10 PF05531.7 EMR72422.1 - 0.084 13.1 3.0 7.8 6.8 0.1 3.6 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF725 PF05267.7 EMR72422.1 - 0.094 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF725) PduV-EutP PF10662.4 EMR72422.1 - 0.12 11.8 0.1 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GATase PF00117.23 EMR72423.1 - 1.1e-07 31.5 0.1 1.8e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I adh_short PF00106.20 EMR72424.1 - 1.2e-17 64.3 0.7 7.3e-12 45.5 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EMR72424.1 - 4.3e-14 52.8 0.1 5.2e-13 49.3 0.0 2.6 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR72424.1 - 0.012 15.2 0.4 0.035 13.7 0.0 1.9 2 0 0 2 2 2 0 KR domain Ribosomal_60s PF00428.14 EMR72424.1 - 0.026 14.9 2.7 0.04 14.3 0.8 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Methyltransf_25 PF13649.1 EMR72424.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ded_cyto PF06920.8 EMR72425.1 - 3.9e-09 36.0 0.1 1.4e-08 34.2 0.1 1.9 1 0 0 1 1 1 1 Dedicator of cytokinesis Sod_Fe_C PF02777.13 EMR72426.1 - 6.9e-35 119.0 0.3 1.2e-34 118.3 0.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EMR72426.1 - 3.1e-30 104.2 1.7 6.4e-30 103.2 0.3 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain JmjC PF02373.17 EMR72427.1 - 1.1e-37 128.7 0.5 2.4e-37 127.6 0.3 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EMR72427.1 - 4.2e-20 71.7 5.6 4.6e-20 71.6 2.9 1.9 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EMR72427.1 - 7.2e-20 70.9 3.4 7.2e-20 70.9 2.3 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.12 EMR72427.1 - 8.8e-14 50.7 1.9 1.7e-13 49.8 1.3 1.5 1 0 0 1 1 1 1 jmjN domain CDC45 PF02724.9 EMR72427.1 - 1.4 6.8 6.2 2.9 5.8 4.3 1.4 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EMR72427.1 - 3.8 7.0 10.2 8.1 5.9 7.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin Nop53 PF07767.6 EMR72427.1 - 4.6 6.1 13.3 1.4 7.8 4.9 2.7 3 0 0 3 3 3 0 Nop53 (60S ribosomal biogenesis) TMF_TATA_bd PF12325.3 EMR72429.1 - 0.0072 16.0 7.1 0.0072 16.0 4.9 2.8 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF4404 PF14357.1 EMR72429.1 - 0.03 14.7 7.6 0.03 14.7 5.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Enkurin PF13864.1 EMR72429.1 - 0.037 14.2 2.2 0.037 14.2 1.6 3.4 3 1 1 4 4 4 0 Calmodulin-binding FlxA PF14282.1 EMR72429.1 - 0.75 9.7 20.9 3.7 7.5 10.5 3.0 2 1 0 2 2 2 0 FlxA-like protein UCR_Fe-S_N PF10399.4 EMR72429.1 - 3.2 6.9 8.7 1.2 8.3 0.0 2.7 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal GST_N_3 PF13417.1 EMR72430.1 - 3.2e-13 49.6 0.0 5.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EMR72430.1 - 3.3e-11 43.0 0.1 6.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMR72430.1 - 6.8e-10 38.9 0.0 1.6e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR72430.1 - 1e-07 31.8 0.0 2.1e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EMR72430.1 - 0.0025 17.6 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR72430.1 - 0.11 13.0 0.1 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GDPD PF03009.12 EMR72431.1 - 8.8e-70 235.1 0.1 1.5e-68 231.0 0.0 2.2 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EMR72431.1 - 5.1e-32 110.0 2.2 1.9e-16 60.1 0.1 4.7 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EMR72431.1 - 8.6e-32 108.9 5.0 1.1e-11 44.8 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.14 EMR72431.1 - 7.8e-30 104.5 6.6 3.5e-17 63.0 1.2 3.6 2 1 1 3 3 3 2 SPX domain Ank PF00023.25 EMR72431.1 - 1e-24 85.0 6.8 1.8e-05 24.3 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 EMR72431.1 - 8.9e-20 70.2 1.4 1.4e-05 25.1 0.0 6.2 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR72431.1 - 9.8e-15 53.2 4.7 0.018 15.2 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat TraD PF06412.6 EMR72431.1 - 0.03 13.8 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 Conjugal transfer protein TraD ER_lumen_recept PF00810.13 EMR72432.1 - 7.2e-51 172.5 7.3 1.1e-50 171.9 5.1 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor Post_transc_reg PF13797.1 EMR72432.1 - 0.15 11.6 0.7 0.27 10.8 0.1 1.7 2 0 0 2 2 2 0 Post-transcriptional regulator AAA PF00004.24 EMR72433.1 - 5.2e-44 149.6 0.0 8.5e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMR72433.1 - 3.1e-08 33.4 0.0 7.5e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EMR72433.1 - 1.2e-07 31.8 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EMR72433.1 - 3.3e-06 27.2 0.0 9.5e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EMR72433.1 - 4.8e-06 26.7 0.1 0.00025 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMR72433.1 - 6.1e-05 23.8 0.0 0.00015 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EMR72433.1 - 7.7e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EMR72433.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EMR72433.1 - 0.00042 19.7 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EMR72433.1 - 0.00089 18.0 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EMR72433.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EMR72433.1 - 0.0017 18.2 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EMR72433.1 - 0.0023 17.5 0.0 0.0074 15.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EMR72433.1 - 0.0023 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EMR72433.1 - 0.0038 17.1 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EMR72433.1 - 0.0065 16.7 0.0 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EMR72433.1 - 0.0068 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EMR72433.1 - 0.0076 15.3 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EMR72433.1 - 0.017 14.5 0.1 0.075 12.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 EMR72433.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EMR72433.1 - 0.019 14.4 0.0 0.085 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.11 EMR72433.1 - 0.019 14.2 0.0 0.07 12.3 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 EMR72433.1 - 0.02 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EMR72433.1 - 0.029 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Histone PF00125.19 EMR72433.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sigma54_activ_2 PF14532.1 EMR72433.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EMR72433.1 - 0.05 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EMR72433.1 - 0.079 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 EMR72433.1 - 0.1 12.2 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain DUF2072 PF09845.4 EMR72433.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Frag1 PF10277.4 EMR72434.1 - 3.9e-16 59.1 1.2 4.9e-16 58.8 0.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3042 PF11240.3 EMR72434.1 - 0.14 12.0 0.6 0.14 12.0 0.4 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) CBFD_NFYB_HMF PF00808.18 EMR72435.1 - 5.2e-05 23.2 0.5 6.2e-05 22.9 0.4 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1980 PF09323.5 EMR72435.1 - 0.094 12.4 0.1 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Peptidase_M41 PF01434.13 EMR72436.1 - 7e-68 228.2 0.7 1.3e-67 227.3 0.5 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EMR72436.1 - 3.8e-43 146.8 0.0 1.2e-42 145.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EMR72436.1 - 3.6e-06 26.7 0.0 1.6e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMR72436.1 - 6.5e-06 26.3 1.1 0.0065 16.6 0.1 3.9 3 1 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EMR72436.1 - 1.1e-05 26.1 0.0 3.4e-05 24.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 EMR72436.1 - 2e-05 23.4 0.0 3.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EMR72436.1 - 0.00014 21.9 4.2 0.00067 19.6 1.1 3.3 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.7 EMR72436.1 - 0.00022 20.3 0.0 0.00051 19.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EMR72436.1 - 0.00067 19.1 0.4 0.005 16.2 0.1 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 EMR72436.1 - 0.0019 18.1 0.1 0.0077 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EMR72436.1 - 0.0032 17.1 1.5 0.006 16.3 0.1 2.2 2 0 0 2 2 1 1 Part of AAA domain AAA_25 PF13481.1 EMR72436.1 - 0.0044 16.4 1.1 0.085 12.2 0.2 2.6 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EMR72436.1 - 0.0061 16.4 0.0 0.02 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EMR72436.1 - 0.0078 15.3 2.9 0.024 13.7 0.3 2.4 1 1 1 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EMR72436.1 - 0.0092 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EMR72436.1 - 0.01 15.0 0.3 0.031 13.4 0.2 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EMR72436.1 - 0.012 15.5 0.4 0.03 14.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EMR72436.1 - 0.023 15.0 0.0 0.071 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EMR72436.1 - 0.11 12.1 0.3 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 NACHT domain LSM PF01423.17 EMR72437.1 - 1.9e-19 68.9 0.3 2.3e-19 68.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain UDPGT PF00201.13 EMR72438.1 - 0.0057 15.2 0.1 0.013 14.0 0.1 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase LicD PF04991.8 EMR72439.1 - 1.1e-31 110.5 4.9 2.4e-17 63.7 0.6 3.4 3 1 0 3 3 3 2 LicD family CAF-1_p150 PF11600.3 EMR72439.1 - 3.6 6.9 6.9 5.5 6.2 4.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal WLM PF08325.5 EMR72441.1 - 2.2e-46 158.0 0.0 3.8e-45 154.0 0.0 2.0 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 EMR72441.1 - 0.00038 20.3 0.6 0.001 18.8 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 EMR72441.1 - 0.0098 15.5 0.1 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 SprT-like family ubiquitin PF00240.18 EMR72441.1 - 0.023 14.1 0.3 0.046 13.1 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin family Peptidase_MA_2 PF13485.1 EMR72441.1 - 0.049 13.6 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily Reprolysin_5 PF13688.1 EMR72441.1 - 0.062 13.2 0.3 0.28 11.0 0.3 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12 CsbD PF05532.7 EMR72442.1 - 0.018 14.7 1.0 0.037 13.7 0.7 1.4 1 0 0 1 1 1 0 CsbD-like Neur_chan_memb PF02932.11 EMR72442.1 - 1.9 8.3 5.2 2 8.2 3.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Prefoldin_2 PF01920.15 EMR72443.1 - 1.7e-24 85.5 5.3 2.3e-24 85.1 3.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit Ecm29 PF13001.2 EMR72443.1 - 0.0029 16.1 0.3 0.0034 15.9 0.2 1.0 1 0 0 1 1 1 1 Proteasome stabiliser DUF3496 PF12001.3 EMR72443.1 - 0.62 10.3 5.3 0.7 10.1 1.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) Fib_alpha PF08702.5 EMR72443.1 - 6.1 6.9 6.8 86 3.2 4.7 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 EMR72443.1 - 7.3 6.1 8.7 21 4.6 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator Amidase PF01425.16 EMR72444.1 - 1.5e-31 109.7 0.1 3.7e-31 108.4 0.0 1.6 2 0 0 2 2 2 1 Amidase PRMT5 PF05185.11 EMR72445.1 - 3.9e-137 457.8 0.0 4.7e-137 457.5 0.0 1.0 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Sugar_tr PF00083.19 EMR72447.1 - 2.2e-72 244.0 33.0 2.5e-72 243.8 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR72447.1 - 4.5e-18 65.0 40.0 1.8e-16 59.8 24.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Romo1 PF10247.4 EMR72447.1 - 0.24 11.6 5.9 0.54 10.4 3.2 2.4 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 MFS_2 PF13347.1 EMR72447.1 - 0.92 7.8 37.5 0.23 9.8 9.0 3.0 2 2 1 3 3 3 0 MFS/sugar transport protein DUF866 PF05907.8 EMR72448.1 - 2.5e-32 111.5 0.4 3e-32 111.3 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Mre11_DNA_bind PF04152.9 EMR72449.1 - 7.1e-49 166.0 0.7 7.1e-49 166.0 0.5 2.6 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EMR72449.1 - 1.5e-13 50.6 2.4 2.5e-13 49.8 1.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_M1 PF01433.15 EMR72450.1 - 6.1e-133 443.6 2.4 6.1e-133 443.6 1.6 1.4 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 EMR72450.1 - 1.5e-63 215.0 0.0 4.3e-63 213.5 0.0 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EMR72450.1 - 4.2e-18 65.6 5.3 4.7e-18 65.4 0.9 2.6 1 1 1 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 EMR72450.1 - 0.19 11.5 2.1 0.29 10.8 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function DUF45 CTP_transf_2 PF01467.21 EMR72451.1 - 0.071 13.1 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Cytidylyltransferase Citrate_ly_lig PF08218.6 EMR72451.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain Tcp11 PF05794.8 EMR72452.1 - 6.1e-45 153.7 0.0 6.1e-45 153.7 0.0 1.7 2 0 0 2 2 2 1 T-complex protein 11 FAD_binding_4 PF01565.18 EMR72453.1 - 2e-22 79.1 0.8 8.2e-22 77.1 0.5 2.0 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR72453.1 - 0.00039 20.2 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like PGAP1 PF07819.8 EMR72455.1 - 0.012 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 EMR72455.1 - 0.022 14.4 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.2 EMR72456.1 - 3.2e-06 26.7 0.1 5.8e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EMR72456.1 - 0.00093 18.7 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain DUF4449 PF14613.1 EMR72457.1 - 1.4e-68 230.0 2.4 1.4e-68 230.0 1.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) YlqD PF11068.3 EMR72457.1 - 0.71 9.9 9.0 0.041 13.9 1.9 2.2 2 0 0 2 2 2 0 YlqD protein DUF1996 PF09362.5 EMR72458.1 - 2.8e-27 95.9 4.9 3.4e-27 95.6 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PseudoU_synth_1 PF01416.15 EMR72460.1 - 8.8e-21 74.3 0.2 5.7e-09 36.3 0.0 3.0 3 0 0 3 3 3 2 tRNA pseudouridine synthase DUF966 PF06136.8 EMR72460.1 - 4.4 6.6 11.2 0.33 10.3 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF966) FAD_binding_4 PF01565.18 EMR72461.1 - 3.9e-20 71.7 2.3 8.6e-20 70.6 1.6 1.6 1 0 0 1 1 1 1 FAD binding domain Asp PF00026.18 EMR72464.1 - 3.1e-22 79.2 0.0 4.8e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.5 EMR72464.1 - 6.1e-08 31.8 0.1 1.3e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 EMR72464.1 - 0.022 14.3 5.1 0.039 13.5 3.5 1.3 1 0 0 1 1 1 0 Podoplanin TAXi_C PF14541.1 EMR72464.1 - 0.039 13.5 0.4 0.099 12.1 0.0 1.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal AcylCoA_DH_N PF12418.3 EMR72464.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal HET PF06985.6 EMR72465.1 - 2.8e-32 111.7 0.1 4.9e-32 111.0 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Med22 PF06179.7 EMR72466.1 - 6.8e-06 26.0 1.8 1e-05 25.5 0.0 2.1 2 2 0 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex peroxidase PF00141.18 EMR72467.1 - 4.5e-30 104.8 0.3 7.1e-30 104.1 0.2 1.3 1 0 0 1 1 1 1 Peroxidase DUF1620 PF07774.8 EMR72469.1 - 3.7e-53 180.0 0.0 7.4e-53 179.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EMR72469.1 - 1.9e-18 66.8 12.2 6.7e-14 51.9 1.7 3.6 4 0 0 4 4 4 2 PQQ-like domain PQQ PF01011.16 EMR72469.1 - 4.8e-07 28.9 3.5 0.011 15.2 0.1 4.6 4 0 0 4 4 4 2 PQQ enzyme repeat WD40 PF00400.27 EMR72470.1 - 1.1e-51 170.9 30.8 1.1e-11 44.1 0.0 11.9 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.7 EMR72470.1 - 3.2e-27 94.5 0.0 4.9e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EMR72470.1 - 2.3e-05 24.1 2.3 0.43 10.2 0.0 5.0 5 1 1 6 6 6 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EMR72470.1 - 0.00046 18.4 1.4 2 6.4 0.0 3.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 IKI3 PF04762.7 EMR72470.1 - 0.00056 17.8 0.0 0.052 11.3 0.0 2.4 2 1 0 2 2 2 2 IKI3 family Nbas_N PF15492.1 EMR72470.1 - 0.0039 16.3 0.2 7.9 5.4 0.0 3.9 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Utp13 PF08625.6 EMR72470.1 - 0.21 11.2 0.1 0.55 9.8 0.1 1.8 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain HMG_box PF00505.14 EMR72471.1 - 3.1e-10 40.1 0.5 4.9e-10 39.5 0.1 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box DUF3761 PF12587.3 EMR72471.1 - 3.9 7.6 6.9 8.1 6.6 4.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3761) MFS_1 PF07690.11 EMR72472.1 - 6.6e-31 107.2 6.1 6.6e-31 107.2 4.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EMR72472.1 - 6e-06 25.1 7.6 6.7e-06 24.9 0.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3098 PF11297.3 EMR72472.1 - 0.081 12.6 0.5 0.081 12.6 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) USP7_ICP0_bdg PF12436.3 EMR72473.1 - 8.3e-82 274.1 0.3 3.8e-79 265.4 0.0 3.2 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EMR72473.1 - 4.6e-73 245.1 3.4 4.4e-68 228.8 0.2 3.6 3 0 0 3 3 3 3 Ubiquitin-specific protease C-terminal UCH PF00443.24 EMR72473.1 - 1.4e-40 139.1 2.1 1.4e-40 139.1 1.4 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EMR72473.1 - 8.1e-17 61.5 0.0 1.6e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EMR72473.1 - 2.5e-12 47.0 0.1 1.1e-11 45.0 0.1 2.2 1 0 0 1 1 1 1 MATH domain adh_short PF00106.20 EMR72474.1 - 4.1e-05 23.5 0.1 6.7e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR72474.1 - 0.0093 15.6 0.1 0.025 14.2 0.0 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EMR72474.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Arylsulfotran_2 PF14269.1 EMR72475.1 - 4.5e-49 167.2 1.8 6.3e-49 166.7 1.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EMR72475.1 - 9.5e-18 63.9 0.4 2.1e-17 62.8 0.3 1.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Xan_ur_permease PF00860.15 EMR72476.1 - 1.9e-25 89.1 30.7 7.8e-25 87.1 20.2 2.3 1 1 1 2 2 2 1 Permease family BCS1_N PF08740.6 EMR72477.1 - 2.3e-38 131.7 0.9 4.7e-38 130.6 0.6 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EMR72477.1 - 6.1e-20 71.7 0.0 4.4e-11 43.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EMR72477.1 - 5.1e-05 24.0 0.0 0.00014 22.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EMR72477.1 - 0.00035 20.0 0.3 0.0015 17.9 0.0 2.2 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.7 EMR72477.1 - 0.007 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EMR72477.1 - 0.0094 15.9 0.5 0.041 13.8 0.4 2.1 1 1 0 1 1 1 1 AAA ATPase domain KaiC PF06745.8 EMR72477.1 - 0.031 13.3 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.1 EMR72477.1 - 0.052 13.4 0.1 0.39 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EMR72477.1 - 0.058 12.9 0.4 0.15 11.6 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EMR72477.1 - 0.083 12.6 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EMR72477.1 - 0.093 13.0 0.1 0.24 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain CASP_C PF08172.7 EMR72478.1 - 1.3e-89 299.4 0.0 1.3e-89 299.4 0.0 4.3 4 1 0 4 4 4 1 CASP C terminal bZIP_2 PF07716.10 EMR72478.1 - 0.0087 15.8 3.5 0.0087 15.8 2.4 7.7 7 1 1 8 8 8 2 Basic region leucine zipper AKNA PF12443.3 EMR72478.1 - 0.23 11.5 13.7 0.39 10.7 0.2 4.6 4 1 0 4 4 4 0 AT-hook-containing transcription factor SlyX PF04102.7 EMR72478.1 - 0.72 10.2 0.0 0.72 10.2 0.0 5.5 6 0 0 6 6 6 0 SlyX V_ATPase_I PF01496.14 EMR72478.1 - 1.3 6.7 28.7 0.24 9.1 3.0 4.1 2 1 2 4 4 4 0 V-type ATPase 116kDa subunit family CVNH PF08881.5 EMR72478.1 - 4 7.7 9.2 0.73 10.0 0.6 3.1 3 1 0 3 3 3 0 CVNH domain ATG16 PF08614.6 EMR72478.1 - 4.1 7.1 50.8 0.99 9.1 0.0 5.7 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) UPF0184 PF03670.8 EMR72478.1 - 4.2 7.6 11.4 1.7 8.8 0.1 4.3 4 1 1 5 5 4 0 Uncharacterised protein family (UPF0184) DUF972 PF06156.8 EMR72478.1 - 7.4 6.9 41.1 2.4 8.5 0.0 6.2 4 2 2 6 6 6 0 Protein of unknown function (DUF972) Shugoshin_N PF07558.6 EMR72478.1 - 8.8 6.1 11.1 0.22 11.2 0.5 3.8 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region FlaC_arch PF05377.6 EMR72478.1 - 9 6.2 22.6 2 8.3 0.2 6.2 5 2 1 7 7 7 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.2 EMR72478.1 - 9.7 6.0 60.2 0.15 11.9 5.8 5.6 4 1 2 6 6 6 0 Tropomyosin like Vps39_2 PF10367.4 EMR72479.1 - 9.9e-09 35.3 0.0 2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 p450 PF00067.17 EMR72480.1 - 4.6e-63 213.3 0.0 1.1e-62 212.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 BCDHK_Adom3 PF10436.4 EMR72481.1 - 4.2e-44 149.9 0.1 6.1e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EMR72481.1 - 3.9e-10 39.4 0.0 9.7e-07 28.4 0.0 2.8 3 0 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EMR72481.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C12 PF01088.16 EMR72482.1 - 3.8e-65 219.0 0.0 5e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Septin PF00735.13 EMR72483.1 - 2.5e-116 387.6 0.4 3.6e-116 387.0 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EMR72483.1 - 7e-07 29.2 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EMR72483.1 - 4.3e-06 26.3 1.1 4.8e-05 22.8 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMR72483.1 - 1.5e-05 24.2 0.0 4.1e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EMR72483.1 - 0.0033 17.0 0.1 0.0067 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EMR72483.1 - 0.0037 17.7 0.8 0.0089 16.5 0.1 2.1 2 0 0 2 2 1 1 Miro-like protein AAA_22 PF13401.1 EMR72483.1 - 0.0069 16.5 0.5 0.024 14.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain IIGP PF05049.8 EMR72483.1 - 0.0082 15.0 0.6 0.014 14.2 0.0 1.7 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.11 EMR72483.1 - 0.01 14.9 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Pox_A32 PF04665.7 EMR72483.1 - 0.012 14.9 0.1 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 EMR72483.1 - 0.015 14.7 1.2 0.02 14.3 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ras PF00071.17 EMR72483.1 - 0.019 14.3 0.8 0.057 12.8 0.3 1.9 2 1 0 2 2 2 0 Ras family DUF2968 PF11180.3 EMR72483.1 - 0.019 14.3 6.0 0.05 12.9 4.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) ABC_tran PF00005.22 EMR72483.1 - 0.039 14.2 0.2 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 EMR72483.1 - 0.04 12.8 0.3 0.093 11.6 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.9 EMR72483.1 - 0.04 12.8 0.9 0.072 12.0 0.6 1.6 1 1 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.7 EMR72483.1 - 0.042 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 EMR72483.1 - 0.058 12.8 0.3 2.5 7.5 0.2 2.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 EMR72483.1 - 0.071 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Dynamin_N PF00350.18 EMR72483.1 - 0.09 12.5 8.1 0.61 9.8 0.1 3.2 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.1 EMR72483.1 - 0.097 12.6 2.6 0.61 10.0 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.17 EMR72483.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase ArgK PF03308.11 EMR72483.1 - 0.12 11.1 2.9 0.98 8.1 0.0 2.9 3 0 0 3 3 3 0 ArgK protein ATP_bind_1 PF03029.12 EMR72483.1 - 0.28 10.6 1.1 9.4 5.6 0.1 2.6 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Ribosomal_L6e PF01159.14 EMR72483.1 - 0.47 10.7 5.8 5.7 7.2 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e Atg14 PF10186.4 EMR72483.1 - 1.2 8.0 8.0 2.4 7.0 5.5 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3455 PF11937.3 EMR72484.1 - 1.2e-45 155.6 0.6 1.6e-45 155.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Glyco_hydro_61 PF03443.9 EMR72485.1 - 0.00014 21.8 0.0 0.0015 18.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 p450 PF00067.17 EMR72486.1 - 3.5e-70 236.8 0.0 8.2e-69 232.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Sel1 PF08238.7 EMR72487.1 - 2.9e-43 145.3 26.2 4e-06 27.2 0.1 7.8 7 0 0 7 7 7 7 Sel1 repeat TPR_17 PF13431.1 EMR72487.1 - 0.015 15.4 0.7 3.9 7.9 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EMR72487.1 - 0.037 14.5 5.6 0.81 10.2 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 EMR72487.1 - 0.16 12.1 1.0 2.9 8.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MPC PF03650.8 EMR72488.1 - 1.2e-41 141.4 0.9 1.6e-41 140.9 0.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Abhydrolase_2 PF02230.11 EMR72489.1 - 1.1e-60 204.7 0.0 1.3e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EMR72489.1 - 3.4e-13 49.5 0.0 7.6e-13 48.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR72489.1 - 1.4e-12 47.9 0.2 1e-05 25.5 0.4 2.7 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 EMR72489.1 - 9.5e-07 28.4 0.0 0.00017 21.0 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EMR72489.1 - 2.5e-06 26.8 0.1 2.2e-05 23.7 0.0 2.3 2 1 1 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.13 EMR72489.1 - 6.2e-05 22.3 0.0 8.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EMR72489.1 - 0.0001 21.9 0.0 0.19 11.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EMR72489.1 - 0.00013 21.6 0.0 0.1 12.1 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2920 PF11144.3 EMR72489.1 - 0.035 13.1 0.0 1.7 7.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) BAAT_C PF08840.6 EMR72489.1 - 0.043 13.5 0.1 0.2 11.3 0.0 2.0 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.9 EMR72489.1 - 0.051 12.7 0.0 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase Cutinase PF01083.17 EMR72489.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Cutinase GFA PF04828.9 EMR72490.1 - 1.3e-22 79.4 0.3 1.9e-22 79.0 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 EMR72490.1 - 0.013 15.2 0.1 0.013 15.2 0.1 1.7 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) LigB PF02900.13 EMR72491.1 - 4.1e-54 183.3 0.1 4.6e-54 183.2 0.1 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Glyco_hydro_32N PF00251.15 EMR72492.1 - 7.3e-49 166.7 0.2 2.1e-44 152.1 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EMR72492.1 - 2.4e-16 59.8 0.0 4.4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal ADH_N PF08240.7 EMR72494.1 - 4e-07 29.7 0.0 7.5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NIL PF09383.5 EMR72494.1 - 0.075 12.6 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 NIL domain Prenylcys_lyase PF07156.9 EMR72494.1 - 0.14 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase GDPD PF03009.12 EMR72496.1 - 1.5e-19 70.5 0.0 2.8e-19 69.6 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family UvrD_C_2 PF13538.1 EMR72497.1 - 8.5e-09 35.4 0.0 2.9e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.1 EMR72497.1 - 9.7e-05 21.8 0.0 0.00044 19.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.1 EMR72497.1 - 0.0033 16.9 0.0 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Cas_Cas4 PF01930.12 EMR72497.1 - 0.015 15.2 0.4 0.03 14.2 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF83 RRM_1 PF00076.17 EMR72498.1 - 1.2e-21 76.1 0.8 1.6e-10 40.4 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR72498.1 - 3.1e-18 65.5 0.0 1.2e-08 34.8 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 EMR72498.1 - 7.7e-16 58.4 0.8 1.1e-15 57.9 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EMR72498.1 - 1.7e-08 34.3 0.3 2.8e-08 33.6 0.2 1.3 1 0 0 1 1 1 1 KR domain RRM_5 PF13893.1 EMR72498.1 - 9.7e-07 28.5 0.7 0.013 15.3 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_10 PF13460.1 EMR72498.1 - 0.0048 16.9 0.8 0.026 14.5 0.2 2.4 3 1 0 3 3 3 1 NADH(P)-binding Nup35_RRM_2 PF14605.1 EMR72498.1 - 0.14 11.9 0.0 0.61 9.9 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Methyltransf_2 PF00891.13 EMR72499.1 - 1.2e-21 77.0 0.0 2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_PK PF05891.7 EMR72499.1 - 0.048 12.9 0.0 0.095 11.9 0.0 1.5 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase CENP-F_leu_zip PF10473.4 EMR72500.1 - 8.1e-07 28.9 16.9 6e-05 22.9 1.8 5.0 1 1 5 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4530 PF15039.1 EMR72500.1 - 0.022 14.6 1.3 0.022 14.6 0.9 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4530) RICH PF05062.7 EMR72500.1 - 0.38 10.8 7.5 0.3 11.2 3.3 2.3 1 1 1 2 2 2 0 RICH domain Reo_sigmaC PF04582.7 EMR72500.1 - 0.81 8.8 14.2 0.15 11.2 0.5 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein WEMBL PF05701.6 EMR72500.1 - 2.3 6.5 58.7 0.55 8.6 21.3 3.1 1 1 2 3 3 3 0 Weak chloroplast movement under blue light DUF1664 PF07889.7 EMR72500.1 - 3.4 7.4 18.2 3.7 7.3 0.1 4.6 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) ETX_MTX2 PF03318.8 EMR72501.1 - 0.13 11.7 4.8 0.19 11.2 3.3 1.1 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 DUF1727 PF08353.5 EMR72501.1 - 0.41 10.2 3.1 1 8.9 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) RPEL PF02755.10 EMR72502.1 - 9.9e-17 59.7 4.1 2.7e-09 36.0 0.2 2.6 2 0 0 2 2 2 2 RPEL repeat tRNA-synt_1 PF00133.17 EMR72503.1 - 2.7e-161 537.6 0.0 3.6e-161 537.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EMR72503.1 - 1.1e-23 83.5 0.0 1.4e-13 50.3 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EMR72503.1 - 3.5e-15 56.0 0.0 6e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 EMR72503.1 - 2.6e-06 26.9 2.6 5.3e-06 25.9 1.8 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 EMR72503.1 - 0.0011 18.1 0.0 0.47 9.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 EMR72503.1 - 0.0028 16.9 0.0 0.0055 16.0 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 DUF945 PF06097.6 EMR72503.1 - 0.35 9.5 0.0 0.55 8.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) FKBP_C PF00254.23 EMR72504.1 - 2e-17 62.9 0.4 1.3e-09 37.9 0.1 2.4 1 1 1 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase Amino_oxidase PF01593.19 EMR72505.1 - 1.2e-27 97.0 0.1 1.6e-27 96.6 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase MFS_1 PF07690.11 EMR72506.1 - 2.1e-33 115.5 31.4 2.7e-33 115.1 21.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PspC PF04024.7 EMR72506.1 - 4.8 6.7 7.8 0.67 9.4 1.2 2.7 3 0 0 3 3 3 0 PspC domain Acetyltransf_1 PF00583.19 EMR72507.1 - 1.2e-15 57.2 0.5 2.3e-15 56.3 0.2 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EMR72507.1 - 6.2e-14 51.9 0.2 1.4e-13 50.7 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EMR72507.1 - 1.9e-07 31.1 0.0 2.8e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EMR72507.1 - 5.3e-07 29.8 0.0 7.3e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EMR72507.1 - 2.8e-06 27.4 0.0 4.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EMR72507.1 - 7.9e-06 25.7 0.0 9.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EMR72507.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.1 EMR72507.1 - 0.067 13.0 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD_binding_3 PF01494.14 EMR72508.1 - 5.5e-16 58.5 0.3 3.4e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EMR72508.1 - 1.4e-06 28.5 0.0 3.5e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR72508.1 - 3.5e-05 23.7 0.6 0.00016 21.5 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EMR72508.1 - 4.9e-05 22.4 1.5 0.00087 18.2 0.5 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EMR72508.1 - 0.0003 19.7 0.9 0.0003 19.7 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EMR72508.1 - 0.00033 20.6 0.2 0.00058 19.8 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR72508.1 - 0.00054 19.7 1.4 0.0046 16.7 1.0 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EMR72508.1 - 0.0011 18.0 0.2 0.072 11.9 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 EMR72508.1 - 0.013 14.5 0.1 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EMR72508.1 - 0.017 13.6 0.5 0.024 13.0 0.3 1.4 1 1 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EMR72508.1 - 0.12 11.8 0.2 0.39 10.2 0.1 1.7 1 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain KTSC PF13619.1 EMR72508.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 KTSC domain GIDA PF01134.17 EMR72508.1 - 0.15 10.9 0.2 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Erythro_esteras PF05139.9 EMR72509.1 - 2.8e-103 345.7 2.2 6.1e-103 344.6 0.3 1.9 1 1 1 2 2 2 1 Erythromycin esterase DUF3738 PF12543.3 EMR72509.1 - 0.071 12.6 0.0 2.3 7.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3738) bact-PGI_C PF10432.4 EMR72509.1 - 0.15 11.7 0.0 0.62 9.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal region IMS PF00817.15 EMR72510.1 - 2.4e-42 144.2 0.0 7.5e-42 142.6 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EMR72510.1 - 6.8e-13 48.6 0.4 3.2e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EMR72510.1 - 0.0014 18.6 0.0 0.0041 17.0 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif Kinesin PF00225.18 EMR72511.1 - 1.2e-108 362.8 0.6 1.2e-108 362.8 0.4 2.4 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 EMR72511.1 - 8.2e-06 26.0 0.4 8.2e-06 26.0 0.3 5.3 3 2 3 6 6 6 2 Kinesin-associated microtubule-binding Apolipoprotein PF01442.13 EMR72511.1 - 0.41 10.1 40.1 0.029 13.9 1.4 4.4 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain ERp29 PF07749.7 EMR72511.1 - 2.5 8.7 10.3 6.1 7.5 0.1 5.2 4 1 1 6 6 6 0 Endoplasmic reticulum protein ERp29, C-terminal domain SPT6_acidic PF14632.1 EMR72512.1 - 0.035 14.2 25.1 1.2 9.3 1.8 3.4 2 1 1 3 3 3 0 Acidic N-terminal SPT6 MFS_1 PF07690.11 EMR72513.1 - 4.2e-35 121.1 23.2 4.2e-35 121.1 16.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PI3Ka PF00613.15 EMR72513.1 - 0.19 10.8 0.1 0.41 9.8 0.0 1.5 2 0 0 2 2 2 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Fungal_trans_2 PF11951.3 EMR72514.1 - 4.5e-13 48.5 0.0 5.7e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.1 EMR72515.1 - 0.098 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EMR72516.1 - 1.1e-26 93.7 1.3 1.7e-26 93.1 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR72516.1 - 1.2e-12 48.1 0.0 1.7e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR72516.1 - 1e-07 31.8 3.6 4.8e-07 29.6 2.5 2.0 1 1 0 1 1 1 1 KR domain HI0933_like PF03486.9 EMR72516.1 - 0.23 9.8 0.6 0.35 9.2 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Pkinase PF00069.20 EMR72517.1 - 2.3e-13 49.9 0.0 3.3e-12 46.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR72517.1 - 0.0061 15.6 0.0 0.099 11.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Cons_hypoth95 PF03602.10 EMR72517.1 - 0.078 12.3 0.0 0.37 10.1 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical protein 95 NACHT PF05729.7 EMR72518.1 - 3.8e-05 23.3 0.0 9.5e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EMR72518.1 - 0.0016 18.4 0.1 0.02 14.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EMR72518.1 - 0.002 18.2 0.0 0.0059 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain HTH_Tnp_Mu_2 PF09039.6 EMR72518.1 - 0.024 14.3 0.1 0.71 9.6 0.0 2.7 2 0 0 2 2 2 0 Mu DNA binding, I gamma subdomain DUF2075 PF09848.4 EMR72518.1 - 0.053 12.4 0.3 0.61 8.9 0.0 2.3 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EMR72518.1 - 0.063 12.6 0.0 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF3661 PF12400.3 EMR72519.1 - 8.6e-43 145.5 6.1 1.5e-42 144.7 4.2 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein SF3b1 PF08920.5 EMR72520.1 - 3.8e-24 85.3 0.7 2.2e-23 82.9 0.0 2.3 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EMR72520.1 - 1.5e-16 60.4 1.7 0.011 16.0 0.0 7.3 6 3 2 8 8 8 6 HEAT repeats HEAT PF02985.17 EMR72520.1 - 4.9e-11 41.7 10.8 0.21 11.7 0.1 9.6 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 EMR72520.1 - 1.4e-10 41.3 1.8 0.77 10.3 0.0 7.7 6 1 1 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EMR72520.1 - 2e-05 24.8 0.9 0.9 9.9 0.0 5.3 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EMR72520.1 - 0.0057 16.0 0.1 0.98 8.7 0.0 3.6 4 0 0 4 4 4 1 CLASP N terminal NUC173 PF08161.7 EMR72520.1 - 0.0098 15.2 0.4 4.9 6.4 0.0 3.7 4 0 0 4 4 4 1 NUC173 domain Dopey_N PF04118.9 EMR72520.1 - 0.12 11.0 0.2 10 4.7 0.0 3.6 4 1 1 5 5 5 0 Dopey, N-terminal MMS19_C PF12460.3 EMR72520.1 - 0.17 10.6 0.0 2.2 6.9 0.0 2.9 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal RRM_1 PF00076.17 EMR72522.1 - 9.5e-13 47.5 0.1 1.4e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR72522.1 - 6.1e-09 35.7 0.0 9.8e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR72522.1 - 3.7e-05 23.4 0.1 5.6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SEP PF08059.8 EMR72522.1 - 0.066 13.5 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 SEP domain PTH2 PF01981.11 EMR72523.1 - 0.077 12.6 0.3 0.86 9.3 0.1 2.4 1 1 1 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 MKT1_C PF12246.3 EMR72525.1 - 1.7e-63 213.8 0.0 2.3e-63 213.4 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EMR72525.1 - 2.4e-25 88.6 0.1 5.3e-25 87.5 0.1 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 EMR72525.1 - 0.0023 18.1 0.0 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain AMP-binding PF00501.23 EMR72526.1 - 6.1e-18 64.4 0.1 1.9e-17 62.7 0.1 1.7 1 1 0 1 1 1 1 AMP-binding enzyme DUF1777 PF08648.7 EMR72527.1 - 2.4e-26 92.5 4.7 3.2e-26 92.1 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) DUF3682 PF12446.3 EMR72527.1 - 1.9 8.7 7.7 3.3 7.9 5.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) Nop14 PF04147.7 EMR72527.1 - 8.3 4.1 10.3 8.1 4.2 7.2 1.0 1 0 0 1 1 1 0 Nop14-like family Elong_Iki1 PF10483.4 EMR72528.1 - 6e-69 232.5 0.0 7.5e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 AA_permease PF00324.16 EMR72529.1 - 2.9e-46 157.8 27.0 3.5e-46 157.5 18.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR72529.1 - 4.1e-14 51.9 30.6 5.4e-14 51.5 21.2 1.1 1 0 0 1 1 1 1 Amino acid permease 2OG-FeII_Oxy PF03171.15 EMR72530.1 - 5e-13 49.1 0.0 8.8e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EMR72531.1 - 6.4e-43 146.8 54.9 1.5e-42 145.6 35.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR72531.1 - 6.1e-15 54.4 21.3 1e-14 53.7 14.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EMR72531.1 - 1.2e-08 33.9 15.0 1.2e-08 33.9 10.4 2.8 1 1 1 3 3 3 1 Sugar (and other) transporter Erythro_esteras PF05139.9 EMR72532.1 - 0.84 8.7 10.5 0.67 9.0 5.0 2.2 2 0 0 2 2 2 0 Erythromycin esterase AflR PF08493.5 EMR72534.1 - 0.00044 19.3 0.5 0.00056 19.0 0.4 1.1 1 0 0 1 1 1 1 Aflatoxin regulatory protein Dicty_REP PF05086.7 EMR72534.1 - 2.5 5.7 4.4 3.8 5.1 3.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ASXH PF13919.1 EMR72535.1 - 1e-21 77.1 0.2 1.9e-21 76.3 0.2 1.4 1 0 0 1 1 1 1 Asx homology domain DUF2264 PF10022.4 EMR72538.1 - 2e-74 250.4 3.1 1.1e-59 201.9 0.1 2.1 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2264) LysM PF01476.15 EMR72538.1 - 0.071 13.0 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 LysM domain Surf_Ag_VNR PF07244.10 EMR72538.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat PAS_10 PF13596.1 EMR72539.1 - 0.059 13.6 0.1 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 PAS domain DNA_pol_E_B PF04042.11 EMR72540.1 - 7.2e-41 139.7 0.2 1.4e-32 112.7 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase alpha/epsilon subunit B Elong-fact-P_C PF09285.6 EMR72540.1 - 0.051 12.9 0.0 0.65 9.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor P, C-terminal Glyco_hydro_63 PF03200.11 EMR72541.1 - 2.5e-234 779.7 0.0 3.1e-233 776.1 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EMR72541.1 - 0.001 17.8 0.0 0.0018 17.0 0.0 1.3 1 0 0 1 1 1 1 Trehalase Zn_clus PF00172.13 EMR72542.1 - 1e-07 31.7 11.8 1.5e-07 31.2 8.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMR72542.1 - 0.00046 19.1 1.2 0.00073 18.4 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dickkopf_N PF04706.7 EMR72542.1 - 1.3 9.2 7.9 2.2 8.4 5.5 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Methyltransf_26 PF13659.1 EMR72543.1 - 1e-11 44.9 0.2 3.6e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EMR72543.1 - 4.5e-06 27.2 0.0 9.4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EMR72543.1 - 4.6e-05 22.8 0.0 0.015 14.6 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.1 EMR72543.1 - 7.1e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EMR72543.1 - 0.00038 19.6 0.0 0.68 8.9 0.0 2.1 2 0 0 2 2 2 2 N-6 DNA Methylase Methyltransf_32 PF13679.1 EMR72543.1 - 0.00083 19.0 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Rhomboid_SP PF12595.3 EMR72543.1 - 0.0074 15.9 4.7 0.015 14.8 3.2 1.5 1 0 0 1 1 1 1 Rhomboid serine protease PrmA PF06325.8 EMR72543.1 - 0.02 13.9 0.0 0.061 12.4 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EMR72543.1 - 0.081 13.2 0.1 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 EMR72543.1 - 0.087 12.3 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 AMP-binding PF00501.23 EMR72544.1 - 2.7e-44 151.2 0.0 3.8e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme polyprenyl_synt PF00348.12 EMR72546.1 - 4.9e-72 241.9 0.0 5.7e-72 241.6 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Sugar_tr PF00083.19 EMR72547.1 - 4.4e-79 266.1 16.0 9.8e-63 212.2 5.2 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EMR72547.1 - 5.7e-14 51.5 3.2 5.7e-14 51.5 2.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily UPF0029 PF01205.14 EMR72548.1 - 1.8e-29 101.6 0.0 2.7e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EMR72548.1 - 1.7e-10 40.7 0.0 3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain AA_permease_2 PF13520.1 EMR72549.1 - 7.2e-63 212.5 38.6 9.6e-63 212.1 26.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EMR72549.1 - 2.2e-29 102.1 32.3 6.5e-29 100.6 22.5 1.7 1 1 0 1 1 1 1 Amino acid permease Tetraspannin PF00335.15 EMR72549.1 - 0.00059 19.1 4.4 0.00059 19.1 3.1 3.0 4 0 0 4 4 4 1 Tetraspanin family TRAPPC9-Trs120 PF08626.6 EMR72550.1 - 6.2e-80 268.9 0.0 1.1e-79 268.2 0.0 1.3 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF2702 PF10863.3 EMR72550.1 - 0.055 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2702) tRNA-synt_1 PF00133.17 EMR72551.1 - 1.6e-34 118.9 5.6 8.7e-19 66.9 0.3 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EMR72551.1 - 1.6e-29 102.8 0.0 3.7e-23 81.8 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EMR72551.1 - 2.5e-12 46.4 0.0 5.1e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 Anticodon_1 PF08264.8 EMR72551.1 - 7.8e-12 45.2 0.0 1.6e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 EMR72551.1 - 0.039 12.7 0.5 0.072 11.8 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (R) p450 PF00067.17 EMR72552.1 - 7.6e-42 143.3 0.0 1e-40 139.6 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 Dynamin_M PF01031.15 EMR72553.1 - 3.2e-104 347.8 0.0 8.3e-104 346.5 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EMR72553.1 - 3.8e-57 192.7 0.1 6.4e-57 192.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EMR72553.1 - 1.5e-29 101.7 5.6 3e-29 100.7 2.5 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EMR72553.1 - 1.5e-05 24.9 0.3 0.00033 20.5 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2226 PF09987.4 EMR72553.1 - 0.015 14.4 0.1 2 7.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2226) Miro PF08477.8 EMR72553.1 - 0.015 15.7 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 EMR72553.1 - 0.052 12.8 0.2 17 4.6 0.0 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B adh_short_C2 PF13561.1 EMR72554.1 - 3.7e-11 43.2 0.0 6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR72554.1 - 4.1e-11 43.0 0.0 8.7e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR72554.1 - 1.9e-05 24.4 0.0 4.3e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 KR domain BAF1_ABF1 PF04684.8 EMR72554.1 - 2.8 6.7 10.8 5.4 5.7 7.5 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RNA_pol_L_2 PF13656.1 EMR72555.1 - 3.9e-20 71.0 0.0 4.9e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EMR72555.1 - 3.5e-06 26.0 0.0 5.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Glyco_hydro_61 PF03443.9 EMR72556.1 - 5.6e-19 68.8 0.0 7.2e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Vps55 PF04133.9 EMR72557.1 - 5.6e-46 155.2 5.0 6.1e-46 155.0 3.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 PepSY_TM_1 PF13172.1 EMR72557.1 - 0.54 10.0 0.1 0.54 10.0 0.1 2.7 3 0 0 3 3 3 0 PepSY-associated TM helix HlyIII PF03006.15 EMR72557.1 - 0.73 9.2 5.7 0.97 8.7 3.9 1.1 1 0 0 1 1 1 0 Haemolysin-III related CLPTM1 PF05602.7 EMR72558.1 - 8.5e-152 505.8 0.0 1e-151 505.5 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Chorismate_bind PF00425.13 EMR72559.1 - 1.2e-57 195.1 0.0 8e-56 189.2 0.0 3.0 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EMR72559.1 - 1.9e-22 79.6 0.0 5e-21 75.0 0.0 2.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EMR72559.1 - 1.3e-15 57.5 0.0 3.1e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EMR72559.1 - 3.7e-05 23.2 0.0 0.00014 21.3 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 WD40 PF00400.27 EMR72560.1 - 4e-28 96.2 10.2 2.2e-07 30.5 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 EMR72560.1 - 7e-18 64.3 0.2 1.2e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EMR72560.1 - 0.022 12.9 7.8 0.098 10.7 0.2 2.8 2 2 0 3 3 3 0 Nucleoporin Nup120/160 Aa_trans PF01490.13 EMR72561.1 - 6.4e-77 258.7 25.8 7.9e-77 258.4 17.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Clr5 PF14420.1 EMR72563.1 - 1.6e-15 56.7 0.5 1.6e-15 56.7 0.3 1.8 2 0 0 2 2 2 1 Clr5 domain NmrA PF05368.8 EMR72564.1 - 3.4e-76 255.5 0.0 4.1e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EMR72564.1 - 0.0027 17.7 0.4 0.013 15.5 0.3 1.9 1 1 0 1 1 1 1 NADH(P)-binding Spt4 PF06093.8 EMR72565.1 - 3.2e-32 110.2 0.6 4.1e-32 109.8 0.4 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger LSM PF01423.17 EMR72567.1 - 1e-20 72.9 0.1 1.2e-20 72.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain RmlD_sub_bind PF04321.12 EMR72568.1 - 1.3e-49 168.6 0.0 1e-48 165.7 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EMR72568.1 - 4e-20 72.2 0.0 5.1e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EMR72568.1 - 2e-10 40.0 0.0 4e-07 29.1 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EMR72568.1 - 3.5e-08 32.4 0.0 1e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EMR72568.1 - 3.6e-08 32.6 0.3 4.9e-06 25.6 0.2 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EMR72568.1 - 3.3e-05 23.9 0.1 6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EMR72568.1 - 0.007 16.2 2.3 0.067 13.1 1.6 2.2 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EMR72568.1 - 0.0096 15.1 0.2 0.14 11.3 0.1 2.6 2 1 0 2 2 2 1 NmrA-like family Longin PF13774.1 EMR72569.1 - 1.1e-23 82.5 0.0 1.6e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EMR72569.1 - 6.5e-17 60.9 0.1 1e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 EMR72569.1 - 0.029 14.1 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lysine_decarbox PF03641.9 EMR72570.1 - 7.6e-28 96.9 0.1 1e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase Proteasome PF00227.21 EMR72571.1 - 9.6e-49 165.2 0.1 1.3e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EMR72571.1 - 2.6e-11 42.6 0.2 5e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Metallophos PF00149.23 EMR72572.1 - 3.7e-38 130.9 0.0 6e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EMR72572.1 - 1.1e-29 102.3 3.3 1.5e-29 101.8 1.1 2.1 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 EMR72572.1 - 2.7e-25 87.7 10.8 3.4e-15 55.4 0.5 2.7 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EMR72572.1 - 3.4e-18 64.4 4.2 1.8e-06 27.3 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMR72572.1 - 2e-14 52.2 2.6 4.9e-05 22.9 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EMR72572.1 - 4.8e-08 32.5 3.1 0.0013 18.7 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EMR72572.1 - 6.2e-06 26.4 0.6 0.051 13.9 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMR72572.1 - 2e-05 24.7 1.8 0.13 12.9 0.0 4.0 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EMR72572.1 - 0.00016 22.2 3.7 0.26 12.0 0.2 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 EMR72572.1 - 0.0024 17.6 0.0 0.046 13.5 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EMR72572.1 - 0.012 15.3 1.0 0.47 10.3 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat CLU PF13236.1 EMR72572.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Clustered mitochondria TPR_6 PF13174.1 EMR72572.1 - 0.023 15.1 1.0 2 9.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 EMR72572.1 - 0.051 12.6 0.2 1.5 7.8 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EMR72572.1 - 0.11 12.4 0.2 14 5.6 0.0 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat 4HBT_3 PF13622.1 EMR72573.1 - 7.4e-18 65.2 8.3 6.2e-16 58.9 5.8 2.6 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EMR72573.1 - 1.6e-05 24.5 0.0 0.0008 19.0 0.0 2.8 3 0 0 3 3 3 1 Acyl-CoA thioesterase DNA_pol_A_exo1 PF01612.15 EMR72574.1 - 3.5e-06 26.6 0.0 4.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease CoA_transf_3 PF02515.12 EMR72575.1 - 2.4e-48 163.9 0.6 3.6e-48 163.3 0.4 1.3 1 0 0 1 1 1 1 CoA-transferase family III Tegument_dsDNA PF12818.2 EMR72576.1 - 0.075 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein adh_short PF00106.20 EMR72577.1 - 2.6e-17 63.2 0.1 4.1e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR72577.1 - 4.2e-08 33.0 0.0 6.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Aminotran_5 PF00266.14 EMR72578.1 - 1.4e-32 112.8 0.0 4.6e-21 74.9 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V APC8 PF04049.8 EMR72579.1 - 6.8e-48 162.0 0.2 6.8e-48 162.0 0.2 2.0 3 0 0 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EMR72579.1 - 2.2e-19 68.1 1.6 0.00058 19.3 0.0 6.0 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 EMR72579.1 - 8.5e-16 57.3 9.3 3e-08 33.1 0.3 6.1 4 1 2 6 6 6 3 TPR repeat TPR_8 PF13181.1 EMR72579.1 - 1.7e-13 49.2 4.8 0.00027 20.5 0.0 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMR72579.1 - 2e-10 39.7 16.3 0.26 11.3 0.0 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 EMR72579.1 - 1.4e-09 37.7 9.7 0.026 15.1 0.0 7.2 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EMR72579.1 - 4.6e-09 36.0 15.4 0.00041 20.2 0.4 5.9 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EMR72579.1 - 7.3e-08 32.8 13.9 3.1e-05 24.5 0.4 6.3 4 2 1 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EMR72579.1 - 1e-05 25.5 5.1 0.083 13.0 0.0 4.8 4 1 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EMR72579.1 - 1.1e-05 24.8 8.9 0.58 10.0 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EMR72579.1 - 0.0001 22.5 6.0 4.5 7.6 0.1 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMR72579.1 - 0.00019 21.1 13.2 0.011 15.5 0.1 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat DUF3856 PF12968.2 EMR72579.1 - 0.00085 19.1 1.4 0.017 14.9 0.1 3.0 1 1 1 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_17 PF13431.1 EMR72579.1 - 0.0053 16.8 1.3 2.6 8.4 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMR72579.1 - 0.023 15.1 15.6 1.7 9.3 0.0 7.9 9 1 1 10 10 7 0 Tetratricopeptide repeat DUF4164 PF13747.1 EMR72579.1 - 0.072 13.2 0.4 0.2 11.7 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF2424 PF10340.4 EMR72579.1 - 0.093 11.3 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) TPR_15 PF13429.1 EMR72579.1 - 0.13 11.3 8.6 0.16 10.9 2.3 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.5 EMR72579.1 - 0.13 11.0 0.0 4.2 6.0 0.0 2.1 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) NMT1 PF09084.6 EMR72581.1 - 1.7e-14 53.9 0.0 2.6e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 EMR72581.1 - 5.3e-06 25.8 0.0 1.1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.2 EMR72581.1 - 0.00047 19.6 0.0 0.00066 19.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.1 EMR72581.1 - 0.0085 15.5 0.0 0.21 10.9 0.0 2.3 1 1 1 2 2 2 1 NMT1-like family Acetyltransf_8 PF13523.1 EMR72581.1 - 0.043 13.7 0.0 12 5.8 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Y_phosphatase3C PF13348.1 EMR72581.1 - 0.05 13.7 0.1 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family C-terminal region RabGAP-TBC PF00566.13 EMR72582.1 - 2.3e-33 115.4 1.0 7.7e-33 113.7 0.1 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EMR72582.1 - 2.6e-10 39.9 0.0 6.3e-05 22.3 0.0 4.3 4 1 0 4 4 4 3 Domain of unknown function (DUF3548) DUF1183 PF06682.7 EMR72582.1 - 0.069 12.7 0.2 0.14 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) ATP-synt_B PF00430.13 EMR72583.1 - 0.36 10.6 18.1 0.058 13.2 9.6 1.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Rifin_STEVOR PF02009.11 EMR72583.1 - 5.1 6.6 15.7 3.7 7.0 7.9 2.4 2 1 0 2 2 2 0 Rifin/stevor family NUDIX PF00293.23 EMR72584.1 - 3.3e-17 62.4 0.6 4e-17 62.1 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.1 EMR72584.1 - 0.028 13.7 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase Fascin PF06268.8 EMR72585.1 - 0.003 17.6 0.0 0.011 15.8 0.0 1.9 1 1 1 2 2 2 1 Fascin domain GFO_IDH_MocA PF01408.17 EMR72587.1 - 4.5e-18 65.9 0.0 8.7e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EMR72587.1 - 9e-16 57.7 0.1 2.3e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EMR72587.1 - 0.091 13.1 0.1 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF4407 PF14362.1 EMR72588.1 - 0.02 13.8 0.4 0.033 13.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WSC PF01822.14 EMR72589.1 - 1.7e-14 53.4 6.2 3.3e-14 52.5 4.3 1.5 1 0 0 1 1 1 1 WSC domain Abhydrolase_5 PF12695.2 EMR72589.1 - 8.5e-06 25.5 0.4 3.1e-05 23.7 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EMR72589.1 - 0.00055 19.8 0.4 0.0022 17.9 0.1 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EMR72589.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 EMR72589.1 - 0.06 12.8 0.1 0.12 11.8 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 EMR72589.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain adh_short PF00106.20 EMR72590.1 - 4.1e-21 75.6 0.7 4.6e-21 75.4 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR72590.1 - 3.6e-10 40.0 0.0 3.9e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EMR72590.1 - 1.5e-06 28.3 0.2 2.3e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EMR72590.1 - 4.6e-06 26.4 0.3 6.3e-06 25.9 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EMR72590.1 - 0.00035 19.8 0.0 0.017 14.3 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EMR72590.1 - 0.0027 17.1 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EMR72590.1 - 0.0094 15.2 0.2 0.012 14.8 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family DFP PF04127.10 EMR72590.1 - 0.016 14.8 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.12 EMR72590.1 - 0.039 12.8 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EMR72590.1 - 0.047 13.4 0.7 0.088 12.6 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PAE PF03283.8 EMR72590.1 - 0.073 11.6 0.2 0.077 11.6 0.2 1.1 1 0 0 1 1 1 0 Pectinacetylesterase Aa_trans PF01490.13 EMR72591.1 - 1.4e-85 287.2 9.2 1.4e-85 287.2 6.4 1.4 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein YfhO PF09586.5 EMR72591.1 - 4.5 5.1 9.7 0.57 8.1 3.6 1.5 1 1 0 1 1 1 0 Bacterial membrane protein YfhO WD40 PF00400.27 EMR72592.1 - 6.9e-30 101.8 3.5 8.4e-05 22.3 0.0 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EMR72592.1 - 2e-06 27.1 0.0 0.029 13.8 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 EMR72592.1 - 0.27 9.4 0.0 14 3.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) DUF3830 PF12903.2 EMR72593.1 - 0.00013 21.3 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) Aconitase PF00330.15 EMR72594.1 - 1.1e-154 515.3 0.0 2.2e-154 514.3 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EMR72594.1 - 4.1e-34 117.5 0.0 6.8e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain BATS PF06968.8 EMR72595.1 - 7.7e-31 105.7 0.2 4e-30 103.5 0.0 2.1 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EMR72595.1 - 9e-14 51.9 0.0 2.8e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily MFS_1 PF07690.11 EMR72596.1 - 2.2e-32 112.1 23.2 2.2e-32 112.1 16.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EMR72596.1 - 0.00096 18.9 3.1 0.077 12.7 1.3 3.0 2 0 0 2 2 2 2 MFS_1 like family Tautomerase PF01361.16 EMR72596.1 - 0.17 11.5 0.1 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Tautomerase enzyme Aminotran_3 PF00202.16 EMR72597.1 - 3.1e-36 124.9 0.0 6.6e-36 123.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.1 EMR72597.1 - 9.5e-26 90.6 0.0 2e-17 63.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain Hydantoinase_B PF02538.9 EMR72598.1 - 2.6e-150 501.1 0.0 4e-150 500.5 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EMR72598.1 - 9e-77 258.0 0.1 2.9e-76 256.3 0.0 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EMR72598.1 - 6e-52 175.6 2.0 2.8e-50 170.2 0.1 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 EMR72598.1 - 0.06 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature SNF2_N PF00176.18 EMR72599.1 - 2e-27 95.7 0.1 3.2e-27 95.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EMR72599.1 - 6e-09 36.0 0.0 2.6e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EMR72599.1 - 0.00065 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EMR72599.1 - 0.0069 15.8 0.4 0.077 12.4 0.3 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase 7tm_7 PF08395.7 EMR72600.1 - 0.044 12.7 0.1 0.05 12.6 0.1 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor YvrJ PF12841.2 EMR72600.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family DUF2723 PF11028.3 EMR72600.1 - 0.62 9.5 5.2 3.3 7.1 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2723) MFS_1 PF07690.11 EMR72601.1 - 1.8e-27 95.9 80.2 3.3e-21 75.4 32.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily His_Phos_2 PF00328.17 EMR72602.1 - 1.1e-22 80.8 0.0 1.5e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) eRF1_1 PF03463.10 EMR72603.1 - 4.2e-37 126.6 0.0 8.1e-37 125.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EMR72603.1 - 1e-23 84.1 0.0 1.6e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EMR72603.1 - 9.8e-19 67.6 0.0 1.9e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 Aldo_ket_red PF00248.16 EMR72604.1 - 6.9e-42 143.2 0.0 9.6e-42 142.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 EMR72605.1 - 1.3e-08 34.4 0.1 5e-05 23.0 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat NAD_binding_10 PF13460.1 EMR72606.1 - 5.8e-11 42.7 0.0 5.5e-05 23.2 0.0 2.2 2 1 0 2 2 2 2 NADH(P)-binding Glyco_hydro_16 PF00722.16 EMR72607.1 - 1.6e-43 148.1 6.7 3.1e-43 147.2 4.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EMR72607.1 - 0.067 13.1 13.0 0.17 11.9 9.0 1.6 1 0 0 1 1 1 0 Chitin recognition protein Lactonase PF10282.4 EMR72608.1 - 5.6e-54 183.4 0.4 7.4e-54 183.1 0.3 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Gmad1 PF10647.4 EMR72608.1 - 0.046 13.1 2.7 3.6 6.9 0.1 2.9 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Myb_DNA-bind_6 PF13921.1 EMR72609.1 - 0.00064 19.7 0.9 0.0025 17.8 0.1 2.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EMR72609.1 - 0.071 13.1 0.4 0.3 11.1 0.3 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Neisseria_TspB PF05616.8 EMR72609.1 - 9.9 4.3 7.9 14 3.8 5.5 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Myb_DNA-binding PF00249.26 EMR72610.1 - 1.2e-13 50.9 1.2 3e-07 30.3 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EMR72610.1 - 8e-13 48.2 0.3 1e-05 25.4 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_38 PF13936.1 EMR72610.1 - 0.05 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Methyltransf_18 PF12847.2 EMR72611.1 - 4.5e-05 23.9 0.0 7.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EMR72611.1 - 0.00017 21.2 0.0 0.00023 20.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EMR72611.1 - 0.00037 20.2 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EMR72611.1 - 0.00055 19.5 0.0 0.00074 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 EMR72611.1 - 0.00087 18.8 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MetW PF07021.7 EMR72611.1 - 0.0019 17.6 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 EMR72611.1 - 0.0021 18.0 0.2 0.004 17.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.12 EMR72611.1 - 0.0099 14.8 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Fibrillarin FtsJ PF01728.14 EMR72611.1 - 0.032 14.2 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 EMR72611.1 - 0.041 14.3 0.1 0.094 13.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EMR72611.1 - 0.054 13.9 0.0 0.081 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EMR72611.1 - 0.075 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EMR72611.1 - 0.1 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EMR72611.1 - 0.11 12.8 0.1 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EMR72611.1 - 0.12 11.4 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Yos1 PF08571.5 EMR72612.1 - 2.8e-28 97.8 0.3 3.1e-28 97.6 0.2 1.0 1 0 0 1 1 1 1 Yos1-like ILVD_EDD PF00920.16 EMR72614.1 - 2.7e-194 646.4 1.3 3.1e-194 646.2 0.9 1.0 1 0 0 1 1 1 1 Dehydratase family Flavodoxin_2 PF02525.12 EMR72615.1 - 6.5e-38 130.2 0.1 7.6e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 EMR72615.1 - 1.5e-11 44.0 0.0 2.3e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 EMR72615.1 - 8.6e-05 21.9 0.3 0.00015 21.1 0.2 1.5 1 1 0 1 1 1 1 Flavodoxin Cyclin PF08613.6 EMR72616.1 - 4.2e-37 127.8 0.0 7.5e-37 127.0 0.0 1.5 1 1 0 1 1 1 1 Cyclin DUF4603 PF15376.1 EMR72616.1 - 0.19 8.8 2.2 0.25 8.4 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Pex14_N PF04695.8 EMR72616.1 - 0.51 10.3 3.8 1.9 8.5 2.6 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M24 PF00557.19 EMR72617.1 - 1.7e-54 184.5 0.0 2.2e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EMR72617.1 - 1.4e-24 86.0 0.0 2.8e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain COesterase PF00135.23 EMR72618.1 - 6.7e-80 269.3 0.0 9.5e-80 268.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family FAD_binding_4 PF01565.18 EMR72618.1 - 1.8e-26 92.3 1.1 3e-26 91.5 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR72618.1 - 4.6e-12 45.6 0.0 1.1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_3 PF07859.8 EMR72618.1 - 4e-06 26.5 0.2 1e-05 25.1 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S10 PF00450.17 EMR72619.1 - 2e-54 185.3 0.4 2.4e-54 185.0 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase adh_short_C2 PF13561.1 EMR72620.1 - 4.5e-27 95.3 0.0 5.6e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR72620.1 - 8.5e-18 64.8 0.6 1.2e-17 64.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.13 EMR72620.1 - 0.07 12.7 0.2 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPP_enzyme_N PF02776.13 EMR72621.1 - 1.7e-39 135.0 0.0 1.1e-38 132.3 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EMR72621.1 - 4.5e-22 78.2 0.0 1e-21 77.0 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMR72621.1 - 2.9e-20 72.4 0.1 8.7e-20 70.8 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain p450 PF00067.17 EMR72622.1 - 8.6e-50 169.5 0.0 1.3e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EMR72623.1 - 5.2e-21 74.5 2.5 8.7e-21 73.8 1.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EMR72623.1 - 3.2e-16 60.3 2.0 5.3e-16 59.6 0.9 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EMR72623.1 - 0.082 12.6 0.0 0.27 11.0 0.0 1.9 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EMR72623.1 - 0.092 12.3 2.4 0.28 10.7 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SIS_2 PF13580.1 EMR72623.1 - 0.23 11.1 1.3 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 SIS domain Peptidase_M49 PF03571.10 EMR72624.1 - 2.6e-125 418.6 0.0 5.7e-95 318.4 0.0 2.0 2 0 0 2 2 2 2 Peptidase family M49 2C_adapt PF08793.5 EMR72624.1 - 0.098 12.5 0.8 0.2 11.5 0.6 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain ECH PF00378.15 EMR72625.1 - 2e-21 76.2 0.2 2.6e-20 72.5 0.1 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family zf-RING_2 PF13639.1 EMR72625.1 - 7.6e-08 32.0 2.1 7.6e-08 32.0 1.4 2.5 3 1 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.2 EMR72625.1 - 1.1e-06 28.6 1.5 1.1e-06 28.6 1.0 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EMR72625.1 - 4.6e-05 23.3 0.2 4.6e-05 23.3 0.1 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EMR72625.1 - 0.0002 21.0 2.4 0.00051 19.8 1.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EMR72625.1 - 0.00069 19.2 1.4 0.00069 19.2 0.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMR72625.1 - 0.0021 17.6 2.1 0.01 15.4 0.4 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EMR72625.1 - 0.0022 17.6 1.7 0.0022 17.6 1.2 2.6 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EMR72625.1 - 0.02 14.7 0.4 0.07 13.0 0.3 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EMR72625.1 - 0.026 14.4 0.6 0.074 13.0 0.4 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EMR72625.1 - 0.046 13.4 0.0 0.19 11.4 0.0 2.1 1 0 0 1 1 1 0 RING-type zinc-finger YdjO PF14169.1 EMR72625.1 - 0.14 11.6 0.8 0.46 9.9 0.1 2.2 2 0 0 2 2 2 0 Cold-inducible protein YdjO Pellino PF04710.9 EMR72625.1 - 0.19 10.3 1.1 0.29 9.7 0.8 1.2 1 0 0 1 1 1 0 Pellino Prok-RING_4 PF14447.1 EMR72625.1 - 6.5 6.3 8.4 13 5.3 2.5 2.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Glyco_hydro_61 PF03443.9 EMR72626.1 - 6.7e-53 179.7 0.4 1e-52 179.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EMR72626.1 - 2e-11 43.3 10.8 4.5e-11 42.2 7.5 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Mucin PF01456.12 EMR72626.1 - 0.029 14.1 41.4 0.062 13.0 28.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein SRPRB PF09439.5 EMR72627.1 - 8.5e-25 87.0 0.0 9e-24 83.6 0.0 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EMR72627.1 - 2.1e-06 27.6 0.0 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EMR72627.1 - 0.00053 19.1 0.1 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EMR72627.1 - 0.00086 19.3 1.6 0.0032 17.4 1.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EMR72627.1 - 0.0013 18.9 0.1 0.0035 17.5 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EMR72627.1 - 0.0016 17.9 0.1 0.14 11.6 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 EMR72627.1 - 0.0071 15.8 0.0 0.049 13.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EMR72627.1 - 0.0093 16.1 0.0 0.018 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain Arf PF00025.16 EMR72627.1 - 0.016 14.4 0.1 0.63 9.2 0.0 2.7 2 1 0 2 2 2 0 ADP-ribosylation factor family AAA_19 PF13245.1 EMR72627.1 - 0.019 14.7 0.5 0.077 12.7 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 EMR72627.1 - 0.032 14.5 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EMR72627.1 - 0.056 12.8 0.2 4.8 6.5 0.0 2.6 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 EMR72627.1 - 0.063 14.0 0.1 0.099 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EMR72627.1 - 0.065 12.3 0.1 0.8 8.8 0.0 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EMR72627.1 - 0.074 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus FeoB_N PF02421.13 EMR72627.1 - 0.11 11.8 0.0 8.8 5.5 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_5 PF07728.9 EMR72627.1 - 0.13 12.0 0.1 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PALP PF00291.20 EMR72628.1 - 3.7e-60 203.7 0.2 5.4e-60 203.1 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EMR72628.1 - 3.4e-10 39.5 0.1 3.7e-09 36.2 0.0 2.5 2 1 0 2 2 2 1 CBS domain Fungal_trans PF04082.13 EMR72629.1 - 1.1e-15 57.2 1.6 1.5e-15 56.7 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EMR72631.1 - 0.046 13.6 9.3 0.11 12.3 6.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2183 PF09949.4 EMR72632.1 - 8.9e-32 109.0 0.0 4.2e-31 106.8 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Zn_clus PF00172.13 EMR72633.1 - 3.7e-06 26.7 11.3 5.8e-06 26.1 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FRQ PF09421.5 EMR72633.1 - 0.68 7.6 4.9 0.91 7.2 3.4 1.1 1 0 0 1 1 1 0 Frequency clock protein PAT1 PF09770.4 EMR72633.1 - 3 5.9 28.8 3.8 5.6 20.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GST_N PF02798.15 EMR72634.1 - 0.067 13.3 0.0 0.08 13.1 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF2470 PF10615.4 EMR72635.1 - 1.4e-14 54.1 0.1 1.9e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 EMR72635.1 - 0.00036 20.4 1.1 0.00064 19.6 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) Zn_clus PF00172.13 EMR72636.1 - 3.6e-10 39.5 6.6 6.8e-10 38.6 4.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EMR72636.1 - 0.00025 20.0 0.1 0.00039 19.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Clusterin PF01093.12 EMR72636.1 - 0.15 10.8 3.4 0.27 9.9 2.3 1.3 1 0 0 1 1 1 0 Clusterin Phosphoesterase PF04185.9 EMR72637.1 - 6.2e-13 48.6 0.0 2.4e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 Phosphoesterase family Glyco_hydro_61 PF03443.9 EMR72638.1 - 2.2e-41 142.0 0.0 7.3e-39 133.8 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 CLN3 PF02487.12 EMR72639.1 - 2e-99 333.1 19.0 1.8e-94 316.8 13.2 3.0 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 EMR72639.1 - 3.3e-09 35.9 8.1 3.6e-05 22.6 0.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PQ-loop PF04193.9 EMR72640.1 - 2e-16 59.2 17.9 3.5e-13 48.8 1.1 3.0 3 0 0 3 3 3 2 PQ loop repeat Peptidase_M50 PF02163.17 EMR72640.1 - 0.065 12.1 1.5 0.3 10.0 0.1 2.1 2 0 0 2 2 2 0 Peptidase family M50 bZIP_1 PF00170.16 EMR72641.1 - 0.0032 17.4 15.1 0.0037 17.1 6.1 2.8 2 1 0 2 2 2 1 bZIP transcription factor HALZ PF02183.13 EMR72641.1 - 0.084 12.5 6.4 0.66 9.7 0.4 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2353 PF09789.4 EMR72641.1 - 0.36 10.0 5.5 0.99 8.6 3.9 1.4 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) BAF1_ABF1 PF04684.8 EMR72644.1 - 0.001 18.0 8.9 0.0014 17.5 6.1 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Ofd1_CTDD PF10637.4 EMR72644.1 - 0.094 11.8 2.2 0.15 11.2 1.5 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term zf-C2H2_4 PF13894.1 EMR72644.1 - 0.34 11.3 5.1 6.9 7.2 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-TFIIB PF13453.1 EMR72644.1 - 0.59 9.3 3.5 0.27 10.4 0.1 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger ILVD_EDD PF00920.16 EMR72645.1 - 7.8e-86 288.5 3.3 9.7e-86 288.2 2.3 1.1 1 0 0 1 1 1 1 Dehydratase family R3H-assoc PF13902.1 EMR72645.1 - 6.2e-17 61.7 0.5 1.5e-16 60.5 0.3 1.6 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 EMR72645.1 - 0.0036 16.9 0.0 0.0083 15.7 0.0 1.6 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EMR72646.1 - 6.9e-09 35.5 0.1 6.1e-08 32.5 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EMR72646.1 - 7.1e-08 32.1 0.0 1.6e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EMR72646.1 - 0.0004 19.9 0.1 0.0042 16.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EMR72646.1 - 0.00055 19.6 0.0 0.31 10.8 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.12 EMR72646.1 - 0.0014 18.6 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 PWI domain DUF1330 PF07045.6 EMR72646.1 - 0.029 14.2 0.1 0.11 12.4 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) DUF4140 PF13600.1 EMR72646.1 - 0.89 10.0 12.7 1.5 9.2 0.1 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMCO5 PF14992.1 EMR72646.1 - 2.7 7.0 10.0 4.4 6.3 6.9 1.2 1 0 0 1 1 1 0 TMCO5 family PHP PF02811.14 EMR72647.1 - 2.5e-09 37.1 0.0 4.4e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 PHP domain adh_short PF00106.20 EMR72648.1 - 9.6e-22 77.6 0.6 1.2e-21 77.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR72648.1 - 5.1e-18 65.7 0.0 6.8e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR72648.1 - 6.4e-05 22.6 0.4 9.8e-05 22.0 0.2 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EMR72648.1 - 0.011 15.3 0.6 0.064 12.9 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EMR72648.1 - 0.082 11.7 1.2 0.11 11.2 0.8 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Globin PF00042.17 EMR72650.1 - 4.7e-10 39.7 0.0 8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 EMR72650.1 - 2.9e-09 37.4 0.0 8.7e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EMR72650.1 - 1.4e-06 28.3 0.0 3e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.3 EMR72650.1 - 3.3e-05 23.6 0.0 6.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 EMR72650.1 - 0.0039 17.0 0.2 0.047 13.6 0.1 2.6 2 1 1 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_1 PF00667.15 EMR72650.1 - 0.097 12.1 0.1 0.21 11.0 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain DUF4515 PF14988.1 EMR72651.1 - 0.069 12.8 0.0 0.069 12.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) Ribonuclease_3 PF00636.21 EMR72652.1 - 2.9e-15 56.7 0.2 1.1e-14 54.8 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EMR72652.1 - 2.3e-11 43.7 0.0 4.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EMR72652.1 - 0.00075 20.0 0.0 0.0041 17.6 0.0 2.1 2 0 0 2 2 2 1 Double-stranded RNA binding motif Aldo_ket_red PF00248.16 EMR72653.1 - 1e-48 165.5 0.0 1.3e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cellulase PF00150.13 EMR72655.1 - 5e-13 48.8 0.4 2.6e-12 46.5 0.3 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) UPF0061 PF02696.9 EMR72656.1 - 3.7e-121 404.8 0.0 4.6e-121 404.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family PUF PF00806.14 EMR72657.1 - 6.6e-37 122.9 5.4 6.1e-08 31.7 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat ACBP PF00887.14 EMR72658.1 - 3.5e-30 103.5 0.1 1e-29 102.0 0.0 1.8 2 0 0 2 2 2 1 Acyl CoA binding protein Perilipin PF03036.11 EMR72658.1 - 1.1 8.0 4.8 1.8 7.3 0.4 2.1 2 0 0 2 2 2 0 Perilipin family Atg14 PF10186.4 EMR72658.1 - 4.2 6.2 8.1 5 5.9 1.0 2.6 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TFIID_20kDa PF03847.8 EMR72659.1 - 0.2 11.9 7.6 6.9 7.0 1.3 3.5 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A PP2C PF00481.16 EMR72660.1 - 2.8e-42 144.8 0.0 6.8e-42 143.6 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EMR72660.1 - 2.1e-05 24.0 0.1 7.8e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 EMR72660.1 - 0.0001 22.0 0.0 0.32 10.6 0.0 3.3 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Molybdopterin PF00384.17 EMR72661.1 - 8.5e-70 235.6 0.0 7.6e-68 229.2 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase DUF1982 PF09326.6 EMR72661.1 - 1.2e-14 54.1 0.0 3.1e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) TPP_enzyme_M PF00205.17 EMR72661.1 - 0.059 13.1 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 EMR72661.1 - 0.25 11.0 1.1 6.5 6.5 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.6 EMR72661.1 - 0.52 10.1 1.9 5.6 6.8 1.3 2.3 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_6 PF12837.2 EMR72661.1 - 1.2 9.1 3.4 1.1 9.2 1.0 1.8 2 0 0 2 2 2 0 4Fe-4S binding domain DUF2985 PF11204.3 EMR72662.1 - 1.8e-28 98.0 4.7 3.4e-28 97.2 3.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) SR-25 PF10500.4 EMR72662.1 - 2.7e-06 27.0 25.7 2.7e-06 27.0 17.8 3.6 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein Period_C PF12114.3 EMR72662.1 - 0.4 10.2 14.6 0.9 9.1 10.2 1.6 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Trypan_PARP PF05887.6 EMR72662.1 - 0.46 10.3 15.2 11 5.7 0.0 2.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Macoilin PF09726.4 EMR72662.1 - 1.7 6.8 16.7 3.4 5.8 11.6 1.5 1 0 0 1 1 1 0 Transmembrane protein Neur_chan_memb PF02932.11 EMR72662.1 - 2.8 7.7 10.9 0.032 14.1 1.6 2.1 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Glycos_transf_1 PF00534.15 EMR72663.1 - 2.1e-22 79.3 0.0 4.4e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EMR72663.1 - 1.6e-11 44.4 0.0 3.4e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EMR72663.1 - 5.9e-06 26.4 0.0 1.6e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.16 EMR72663.1 - 0.03 12.8 0.0 0.043 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 20 Aldolase_II PF00596.16 EMR72664.1 - 3e-39 134.5 1.6 3.8e-39 134.2 0.6 1.5 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain CUE PF02845.11 EMR72665.1 - 2.3e-11 42.9 0.0 3.9e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain DIL PF01843.14 EMR72666.1 - 1.4e-17 63.4 3.7 9.4e-16 57.5 2.5 2.3 1 1 0 1 1 1 1 DIL domain Ank_2 PF12796.2 EMR72666.1 - 9.9e-16 57.8 0.1 3.2e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EMR72666.1 - 5.1e-14 51.2 0.0 1.8e-05 24.3 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EMR72666.1 - 1.1e-11 44.8 0.1 2.8e-05 24.4 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR72666.1 - 3.2e-11 43.0 0.0 1.7e-05 24.8 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR72666.1 - 2.4e-07 30.3 0.0 0.031 14.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat DUF1168 PF06658.7 EMR72667.1 - 1.2e-37 128.5 20.3 4.4e-37 126.7 14.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) DNA_pol3_a_NII PF11490.3 EMR72667.1 - 3.9 7.1 7.0 6.4 6.4 4.8 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Herpes_DNAp_acc PF04929.7 EMR72667.1 - 6 5.7 5.5 9.2 5.1 3.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Cupin_2 PF07883.6 EMR72668.1 - 9.5e-09 34.6 0.0 1.8e-08 33.7 0.0 1.5 1 1 1 2 2 2 1 Cupin domain Cupin_3 PF05899.7 EMR72668.1 - 0.01 15.2 0.1 0.06 12.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EMR72668.1 - 0.016 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Cupin Auxin_BP PF02041.11 EMR72668.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein DnaJ PF00226.26 EMR72669.1 - 3.6e-24 84.2 1.4 3.6e-24 84.2 1.0 2.3 2 0 0 2 2 2 1 DnaJ domain Metallophos_2 PF12850.2 EMR72670.1 - 2.8e-13 50.0 0.0 3.3e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EMR72670.1 - 0.13 11.5 0.1 0.56 9.5 0.0 1.8 1 1 0 2 2 2 0 Calcineurin-like phosphoesterase Allantoicase PF03561.10 EMR72671.1 - 7.7e-106 350.1 0.1 4.2e-56 188.6 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Cytochrom_B561 PF03188.11 EMR72672.1 - 1.7e-16 60.2 7.3 1.7e-16 60.2 5.1 2.2 2 1 1 3 3 3 2 Eukaryotic cytochrome b561 CybS PF05328.7 EMR72672.1 - 0.078 12.6 1.2 0.99 9.0 0.0 2.5 1 1 1 2 2 2 0 CybS PsbR PF04725.7 EMR72672.1 - 0.14 12.2 0.4 0.27 11.2 0.3 1.5 1 0 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR MttA_Hcf106 PF02416.11 EMR72672.1 - 0.18 10.9 6.0 0.48 9.5 4.2 1.7 1 0 0 1 1 1 0 mttA/Hcf106 family DUF1129 PF06570.6 EMR72672.1 - 0.47 9.7 11.1 0.19 10.9 5.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Holin_BlyA PF05102.7 EMR72672.1 - 1.6 8.5 5.4 0.99 9.1 0.6 2.4 2 0 0 2 2 2 0 holin, BlyA family DUF4079 PF13301.1 EMR72672.1 - 2.3 8.1 15.8 0.33 10.9 1.8 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4079) Ferric_reduct PF01794.14 EMR72672.1 - 7.3 6.7 12.8 2 8.5 6.5 1.8 1 1 1 2 2 2 0 Ferric reductase like transmembrane component DUF2298 PF10060.4 EMR72674.1 - 0.16 10.8 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) Tetraspannin PF00335.15 EMR72675.1 - 0.0011 18.2 5.7 0.012 14.8 4.0 2.1 1 1 0 1 1 1 1 Tetraspanin family Lung_7-TM_R PF06814.8 EMR72675.1 - 0.047 12.6 0.1 0.068 12.1 0.1 1.1 1 0 0 1 1 1 0 Lung seven transmembrane receptor RabGAP-TBC PF00566.13 EMR72676.1 - 1.2e-32 113.1 0.0 1.7e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Synaphin PF05835.7 EMR72676.1 - 0.11 12.6 5.0 0.25 11.4 3.3 1.6 2 0 0 2 2 2 0 Synaphin protein Cpn60_TCP1 PF00118.19 EMR72677.1 - 1.9e-158 528.0 0.1 2.2e-158 527.8 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Shugoshin_C PF07557.6 EMR72678.1 - 2.5e-10 39.6 4.8 2.5e-10 39.6 3.3 3.0 3 0 0 3 3 3 1 Shugoshin C terminus CRM1_C PF08767.6 EMR72679.1 - 6.6e-116 386.6 2.3 6.6e-116 386.6 1.6 3.2 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EMR72679.1 - 1.6e-40 138.3 7.2 1.6e-40 138.3 5.0 3.6 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EMR72679.1 - 3.3e-14 52.5 1.2 1e-13 50.9 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3385 PF11865.3 EMR72679.1 - 0.047 13.6 3.4 0.092 12.6 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.2 EMR72679.1 - 0.053 13.9 1.5 3.3 8.1 0.0 4.3 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region C8 PF08742.6 EMR72679.1 - 0.074 13.3 0.7 1 9.6 0.0 2.9 3 0 0 3 3 3 0 C8 domain Folate_rec PF03024.9 EMR72679.1 - 0.15 11.6 2.0 1.5 8.3 0.3 2.3 2 0 0 2 2 2 0 Folate receptor family HD_assoc PF13286.1 EMR72679.1 - 0.19 12.0 3.4 28 5.0 0.0 4.1 5 0 0 5 5 5 0 Phosphohydrolase-associated domain Response_reg PF00072.19 EMR72680.1 - 4.5e-22 78.1 0.1 6.3e-21 74.4 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EMR72680.1 - 1.1e-21 76.5 0.3 3.9e-21 74.8 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.21 EMR72680.1 - 3.3e-19 68.6 0.2 6.6e-19 67.6 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.6 EMR72680.1 - 2.9e-08 33.6 0.0 0.00073 19.5 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EMR72680.1 - 9.8e-05 22.6 0.0 0.0078 16.5 0.0 3.1 1 1 1 2 2 2 1 PAS domain PAS PF00989.19 EMR72680.1 - 0.023 14.4 0.0 0.067 12.9 0.0 1.8 1 0 0 1 1 1 0 PAS fold DUF1445 PF07286.7 EMR72681.1 - 7.5e-55 184.5 0.0 1.1e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) DUF605 PF04652.11 EMR72682.1 - 0.14 11.5 7.0 0.17 11.2 4.8 1.0 1 0 0 1 1 1 0 Vta1 like Aminotran_5 PF00266.14 EMR72683.1 - 3.8e-25 88.4 0.0 5e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 EMR72683.1 - 0.00014 21.7 0.1 0.017 14.9 0.0 2.5 2 0 0 2 2 2 2 B12 binding domain Aminotran_1_2 PF00155.16 EMR72683.1 - 0.00016 20.7 0.0 0.00031 19.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II HA2 PF04408.18 EMR72686.1 - 1.9e-22 79.1 0.1 1.9e-21 75.9 0.1 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EMR72686.1 - 9.1e-22 77.0 0.0 1.9e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EMR72686.1 - 1.6e-11 43.8 0.0 3.3e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EMR72686.1 - 5.7e-05 23.2 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EMR72686.1 - 0.021 13.9 0.3 0.13 11.3 0.0 2.3 2 1 1 3 3 3 0 Zeta toxin cobW PF02492.14 EMR72686.1 - 0.029 13.8 0.2 0.39 10.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EMR72686.1 - 0.048 13.9 0.1 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EMR72686.1 - 0.052 12.4 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EMR72686.1 - 0.059 13.1 0.1 0.17 11.6 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EMR72686.1 - 0.081 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EMR72686.1 - 0.086 12.7 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EMR72686.1 - 0.098 12.1 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DASH_Dad2 PF08654.5 EMR72687.1 - 2.3e-26 91.7 2.0 9e-26 89.8 1.4 2.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Piwi PF02171.12 EMR72688.1 - 2.4e-61 207.3 0.5 1.1e-58 198.6 0.3 2.2 1 1 0 1 1 1 1 Piwi domain PAZ PF02170.17 EMR72688.1 - 1.1e-09 37.7 0.0 3.1e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EMR72688.1 - 2.4e-09 36.4 0.0 3.5e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) Stn1 PF10451.4 EMR72689.1 - 8.6e-08 31.3 0.8 1.7e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 EMR72689.1 - 3.6e-06 26.7 0.7 1.1e-05 25.2 0.5 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Herpes_U5 PF05999.6 EMR72689.1 - 0.025 13.1 0.1 0.031 12.8 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus U5-like family Nucleo_P87 PF07267.6 EMR72689.1 - 0.038 12.6 0.5 0.044 12.4 0.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Glyco_hydro_81 PF03639.8 EMR72690.1 - 1.6e-178 594.9 6.6 5.8e-177 589.8 2.5 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 81 UPF0016 PF01169.14 EMR72690.1 - 0.077 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 His_Phos_1 PF00300.17 EMR72691.1 - 6.1e-33 114.1 0.0 1.2e-32 113.1 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EMR72691.1 - 0.0097 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1977 PF09320.6 EMR72692.1 - 1.6e-19 70.0 0.0 1.9e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DUF977 PF06163.6 EMR72692.1 - 0.056 13.1 0.1 0.92 9.2 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF977) adh_short PF00106.20 EMR72693.1 - 9.6e-19 67.9 2.6 1.2e-18 67.5 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR72693.1 - 6.9e-13 48.6 0.5 9.3e-13 48.2 0.3 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR72693.1 - 1.3e-07 31.6 0.1 1.6e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR72693.1 - 1.7e-05 24.3 0.1 2.4e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EMR72693.1 - 3.6e-05 22.8 0.0 4.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MFS_1 PF07690.11 EMR72694.1 - 1.2e-18 67.0 22.6 1.5e-18 66.6 15.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1996 PF09362.5 EMR72695.1 - 6.9e-61 205.9 0.2 8.7e-61 205.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) adh_short PF00106.20 EMR72696.1 - 1.4e-14 54.3 0.3 2.5e-14 53.5 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR72696.1 - 2.1e-07 30.8 0.2 4.6e-07 29.6 0.1 1.6 1 1 1 2 2 2 1 KR domain Saccharop_dh PF03435.13 EMR72696.1 - 1.2e-05 24.5 0.2 2.1e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short_C2 PF13561.1 EMR72696.1 - 2.7e-05 24.0 0.1 4.3e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EMR72696.1 - 0.00015 21.8 0.1 0.00029 20.9 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EMR72696.1 - 0.015 14.2 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Cu-oxidase_2 PF07731.9 EMR72697.1 - 1.3e-09 37.6 0.0 1.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Multicopper oxidase AAA PF00004.24 EMR72698.1 - 5.7e-18 65.3 0.0 1.1e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EMR72698.1 - 9.1e-05 22.5 0.0 0.00034 20.6 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.9 EMR72698.1 - 0.00013 21.7 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMR72698.1 - 0.00032 20.8 0.1 0.0015 18.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EMR72698.1 - 0.00033 21.4 0.0 0.0011 19.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMR72698.1 - 0.00062 19.4 0.1 0.0016 18.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EMR72698.1 - 0.0016 18.7 0.0 0.0082 16.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain Zot PF05707.7 EMR72698.1 - 0.0028 17.1 0.2 0.058 12.8 0.1 2.3 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_28 PF13521.1 EMR72698.1 - 0.0046 16.9 0.1 0.097 12.6 0.0 2.9 2 1 1 3 3 3 1 AAA domain ArgK PF03308.11 EMR72698.1 - 0.0062 15.3 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_14 PF13173.1 EMR72698.1 - 0.0065 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EMR72698.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EMR72698.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EMR72698.1 - 0.018 14.4 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.1 EMR72698.1 - 0.027 14.0 0.2 0.086 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EMR72698.1 - 0.031 13.3 0.5 0.099 11.7 0.1 1.8 1 1 1 2 2 2 0 KaiC AAA_11 PF13086.1 EMR72698.1 - 0.04 13.4 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EMR72698.1 - 0.054 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EMR72698.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EMR72698.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Tim17 PF02466.14 EMR72700.1 - 2.2e-38 131.2 4.7 2.5e-38 130.9 3.2 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ebp2 PF05890.7 EMR72701.1 - 3.4e-91 305.3 6.2 3.4e-91 305.3 4.3 2.9 1 1 1 3 3 3 1 Eukaryotic rRNA processing protein EBP2 TMEMspv1-c74-12 PF11044.3 EMR72701.1 - 4.4 6.9 7.9 18 5.0 5.4 2.0 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Glyco_hydro_16 PF00722.16 EMR72702.1 - 1.8e-10 40.4 0.1 5.8e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 PIG-P PF08510.7 EMR72702.1 - 0.006 16.2 0.2 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 PIG-P Spb1_C PF07780.7 EMR72703.1 - 2.5e-76 255.9 23.6 2.5e-76 255.9 16.4 2.5 2 1 1 3 3 3 1 Spb1 C-terminal domain Fungal_trans_2 PF11951.3 EMR72704.1 - 1.7e-07 30.1 0.3 2.3e-07 29.7 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF885 PF05960.6 EMR72705.1 - 2.3e-50 172.2 0.0 4.1e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) PSII_Pbs27 PF13326.1 EMR72705.1 - 0.13 12.2 0.3 0.7 9.8 0.2 2.2 1 1 0 1 1 1 0 Photosystem II Pbs27 HMG_box PF00505.14 EMR72706.1 - 4.4e-06 26.8 0.4 8.9e-06 25.8 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Peptidase_M20 PF01546.23 EMR72707.1 - 8.2e-23 80.8 0.0 8.5e-22 77.5 0.0 2.5 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EMR72707.1 - 1.3e-08 34.3 0.0 0.0046 16.8 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat M20_dimer PF07687.9 EMR72707.1 - 2.9e-08 33.4 0.0 5.2e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EMR72707.1 - 0.006 16.3 0.0 0.023 14.4 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_A4 PF01828.12 EMR72708.1 - 1.3e-31 109.2 9.3 1.5e-31 109.0 6.5 1.0 1 0 0 1 1 1 1 Peptidase A4 family Tim17 PF02466.14 EMR72709.1 - 1.5e-34 118.8 5.7 1.8e-34 118.5 3.9 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 EMR72709.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal Asparaginase_2 PF01112.13 EMR72710.1 - 7.8e-40 136.5 0.1 7.7e-22 77.4 0.1 4.6 5 0 0 5 5 5 4 Asparaginase DUF1996 PF09362.5 EMR72711.1 - 1.9e-89 299.3 0.6 2.2e-89 299.1 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CTD PF12815.2 EMR72712.1 - 3.9e-24 85.4 71.6 7.1e-17 61.9 28.6 4.8 1 1 3 4 4 4 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 EMR72712.1 - 7.6e-24 83.2 0.0 1.5e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EMR72712.1 - 3e-12 46.9 16.1 3e-12 46.9 11.1 3.4 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EMR72712.1 - 9.8e-06 25.0 17.7 0.0027 17.3 0.8 6.0 6 0 0 6 6 6 2 KOW motif Exo_endo_phos PF03372.18 EMR72713.1 - 4.3e-06 26.8 1.7 6.3e-06 26.2 1.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.12 EMR72713.1 - 5.7e-06 26.2 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Ank_2 PF12796.2 EMR72714.1 - 2.7e-32 110.9 0.1 1.1e-12 48.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMR72714.1 - 6.1e-20 69.9 5.7 0.0011 18.6 0.1 6.4 6 1 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EMR72714.1 - 1.5e-19 68.1 0.6 0.0026 17.8 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EMR72714.1 - 9.5e-13 48.2 2.1 0.068 13.7 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EMR72714.1 - 3.8e-10 39.6 4.7 0.023 14.9 0.0 5.8 4 2 2 6 6 6 3 Ankyrin repeats (many copies) CYSTM PF12734.2 EMR72714.1 - 0.2 11.7 4.3 0.07 13.2 0.9 1.8 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Glyco_hydro_61 PF03443.9 EMR72715.1 - 5e-55 186.6 0.0 5.7e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_M22 PF00814.20 EMR72717.1 - 0.064 12.7 0.2 0.13 11.7 0.1 1.5 1 1 0 1 1 1 0 Glycoprotease family DUF4472 PF14739.1 EMR72717.1 - 0.077 13.4 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Pyr_redox_2 PF07992.9 EMR72718.1 - 7.8e-16 58.5 0.3 1.3e-14 54.5 0.2 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR72718.1 - 3.8e-08 33.6 0.1 1.9e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR72718.1 - 0.3 11.1 3.3 14 5.8 0.0 3.3 2 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain DUF3888 PF13027.1 EMR72720.1 - 0.15 11.9 1.4 0.19 11.6 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) Ank_2 PF12796.2 EMR72721.1 - 1.5e-19 70.0 0.3 6.7e-09 35.9 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EMR72721.1 - 1.7e-17 62.2 1.3 8.3e-07 28.5 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EMR72721.1 - 1.7e-16 59.8 1.0 1.5e-05 25.0 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EMR72721.1 - 1.5e-14 54.0 0.1 0.00032 21.1 0.0 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EMR72721.1 - 5.6e-14 50.8 0.2 0.00075 19.5 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat RHH_1 PF01402.16 EMR72721.1 - 0.097 12.6 0.1 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family DNA_pol_B PF00136.16 EMR72722.1 - 1.5e-147 492.1 4.2 2e-147 491.7 2.9 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EMR72722.1 - 5.2e-77 258.8 0.1 1.2e-76 257.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EMR72722.1 - 7.6e-23 80.3 3.7 7.6e-23 80.3 2.6 1.9 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EMR72722.1 - 0.0013 18.5 0.2 0.0063 16.3 0.1 2.2 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EMR72722.1 - 0.0018 17.8 0.1 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.17 EMR72722.1 - 0.0094 15.6 6.0 0.37 10.5 0.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_M48 PF01435.13 EMR72723.1 - 8.2e-19 68.0 0.0 5.5e-13 49.0 0.0 2.6 2 1 1 3 3 3 2 Peptidase family M48 ELFV_dehydrog_N PF02812.13 EMR72724.1 - 7.3e-48 161.4 0.0 9.7e-48 161.0 0.0 1.2 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.16 EMR72724.1 - 4.8e-14 52.5 0.4 7.1e-14 51.9 0.3 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase p450 PF00067.17 EMR72725.1 - 1.9e-50 171.7 0.0 2.3e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BMP2K_C PF15282.1 EMR72726.1 - 0.049 13.8 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus LIM PF00412.17 EMR72729.1 - 1.6e-20 72.9 10.8 4.9e-10 39.3 2.0 2.1 2 0 0 2 2 2 2 LIM domain WRC PF08879.5 EMR72729.1 - 0.038 13.6 0.2 0.15 11.7 0.1 2.0 2 0 0 2 2 2 0 WRC Yippee-Mis18 PF03226.9 EMR72729.1 - 0.22 11.5 1.8 0.32 11.0 1.3 1.2 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ribosomal_L37ae PF01780.14 EMR72729.1 - 0.4 10.5 3.9 6.6 6.6 0.3 2.5 2 1 0 2 2 2 0 Ribosomal L37ae protein family C1_3 PF07649.7 EMR72729.1 - 2.2 8.3 7.5 3 7.9 0.1 3.3 3 0 0 3 3 3 0 C1-like domain NAD_binding_5 PF07994.7 EMR72730.1 - 7.4e-109 363.7 0.0 8.7e-109 363.5 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EMR72730.1 - 7.9e-45 151.2 0.1 1.3e-44 150.5 0.1 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF3405 PF11885.3 EMR72731.1 - 2.7e-169 563.5 6.7 3.6e-167 556.5 4.7 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) MFS_1 PF07690.11 EMR72732.1 - 3e-36 124.8 69.1 9.6e-32 110.0 39.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 EMR72733.1 - 2.3e-36 125.8 0.0 2.8e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR72733.1 - 2e-18 66.8 0.1 2.2e-15 56.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EMR72733.1 - 2.7e-17 62.8 0.0 4.6e-17 62.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EMR72733.1 - 2e-05 23.1 0.0 9.7e-05 20.9 0.0 1.8 2 0 0 2 2 2 1 Ndr family Peptidase_S9 PF00326.16 EMR72733.1 - 0.0012 18.0 0.0 0.06 12.5 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family PhoPQ_related PF10142.4 EMR72733.1 - 0.0032 16.0 0.0 0.024 13.1 0.0 1.9 1 1 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Esterase_phd PF10503.4 EMR72733.1 - 0.082 12.1 0.0 3.3 6.8 0.0 2.8 3 1 1 4 4 4 0 Esterase PHB depolymerase Gemini_mov PF01708.11 EMR72734.1 - 0.15 11.6 0.2 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein GST_N_3 PF13417.1 EMR72736.1 - 1.8e-14 53.7 0.0 3e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EMR72736.1 - 2.8e-14 52.8 0.2 4.5e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMR72736.1 - 4.9e-13 48.8 0.0 8.6e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EMR72736.1 - 3.9e-12 46.1 0.0 6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR72736.1 - 3e-10 39.8 0.0 5.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EMR72736.1 - 0.00019 21.8 0.0 0.00028 21.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3067 PF11267.3 EMR72736.1 - 0.0032 17.5 0.1 0.006 16.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3067) LETM1 PF07766.8 EMR72738.1 - 1.8e-07 30.4 0.0 4.6e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 LETM1-like protein Pkinase PF00069.20 EMR72739.1 - 3.3e-58 196.8 0.0 4.5e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR72739.1 - 1.9e-25 89.4 0.0 2.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EMR72739.1 - 2.5e-06 26.6 0.0 4.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EMR72739.1 - 0.00055 19.7 0.7 0.00082 19.1 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMR72739.1 - 0.0012 17.9 0.0 0.0039 16.2 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family KicB PF03882.9 EMR72739.1 - 0.028 13.0 0.0 0.052 12.1 0.0 1.4 1 0 0 1 1 1 0 KicB killing factor YrbL-PhoP_reg PF10707.4 EMR72739.1 - 0.062 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF302 PF03625.9 EMR72740.1 - 5.1e-06 25.9 0.2 7.2e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF302 DUF3992 PF13157.1 EMR72740.1 - 0.027 14.6 0.1 0.04 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) DUF1308 PF07000.6 EMR72741.1 - 8.5e-37 126.6 0.0 1.4e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Pyridox_oxidase PF01243.15 EMR72742.1 - 0.0013 18.7 0.0 0.02 14.8 0.0 2.2 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF892 PF05974.7 EMR72743.1 - 0.0026 17.6 0.1 0.0037 17.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF892) p450 PF00067.17 EMR72744.1 - 1.9e-34 118.9 0.3 2.4e-34 118.6 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 EMR72745.1 - 2.9e-19 69.6 0.7 3.3e-19 69.4 0.5 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PAP2 PF01569.16 EMR72747.1 - 3.1e-13 49.5 7.5 4.8e-13 48.9 5.2 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EMR72747.1 - 6.4e-06 25.8 8.8 1.7e-05 24.4 6.1 1.6 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 EMR72747.1 - 0.0083 16.3 3.9 0.021 15.0 2.7 1.7 1 0 0 1 1 1 1 PAP2 superfamily C-terminal EthD PF07110.6 EMR72748.1 - 4.6e-07 30.6 1.2 2.1e-06 28.5 0.8 1.8 1 1 0 1 1 1 1 EthD domain Glyco_hydro_17 PF00332.13 EMR72749.1 - 5.9e-10 38.6 1.3 2.2e-05 23.6 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF3169 PF11368.3 EMR72749.1 - 0.0071 15.5 0.2 0.0071 15.5 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) CRA PF06589.6 EMR72749.1 - 0.03 13.6 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Herpes_US9 PF06072.6 EMR72749.1 - 0.031 14.0 0.4 0.066 13.0 0.3 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF937 PF06078.6 EMR72749.1 - 0.032 14.4 7.5 4 7.6 0.0 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF937) DUF4179 PF13786.1 EMR72749.1 - 0.043 14.0 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF2076 PF09849.4 EMR72749.1 - 0.13 12.2 2.8 0.23 11.5 1.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Gly-zipper_YMGG PF13441.1 EMR72749.1 - 0.24 10.9 21.1 1.1 8.7 14.6 2.0 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 EMR72749.1 - 0.8 9.3 21.7 0.54 9.9 3.1 2.4 2 0 0 2 2 2 0 Glycine zipper ETRAMP PF09716.5 EMR72749.1 - 0.97 9.4 3.4 0.82 9.6 0.2 2.0 1 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Gly-zipper_OmpA PF13436.1 EMR72749.1 - 8.9 6.0 15.3 9.4 5.9 0.2 2.4 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain HrpB7 PF09486.5 EMR72750.1 - 0.032 14.1 0.9 0.054 13.4 0.6 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Dioxygenase_C PF00775.16 EMR72752.1 - 9.5e-34 116.2 0.0 1.5e-26 92.7 0.0 2.1 1 1 1 2 2 2 2 Dioxygenase Polysacc_deac_1 PF01522.16 EMR72753.1 - 1.1e-16 60.6 0.1 7.2e-16 57.9 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EMR72753.1 - 7.8e-07 28.9 20.5 7.8e-07 28.9 14.2 3.0 3 1 0 3 3 3 1 Chitin recognition protein Glyco_hydro_57 PF03065.10 EMR72753.1 - 0.095 11.5 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Phos_pyr_kin PF08543.7 EMR72754.1 - 5.5e-81 271.3 0.1 7.2e-81 270.9 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EMR72754.1 - 5.1e-24 85.1 0.1 1.5e-21 77.1 0.0 3.0 1 1 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EMR72754.1 - 2.2e-10 40.1 0.0 4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 EMR72754.1 - 0.022 13.9 0.7 0.49 9.5 0.5 2.3 1 1 0 1 1 1 0 Hydroxyethylthiazole kinase family Carb_kinase PF01256.12 EMR72754.1 - 0.2 10.9 1.3 1.1 8.5 0.9 2.1 1 1 0 1 1 1 0 Carbohydrate kinase HMA PF00403.21 EMR72755.1 - 6.2e-15 55.0 0.3 2.5e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Heavy-metal-associated domain Sod_Cu PF00080.15 EMR72755.1 - 1e-10 41.9 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) RICTOR_N PF14664.1 EMR72757.1 - 4.7e-78 262.3 3.5 4.8e-61 206.4 0.8 2.5 1 1 1 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.1 EMR72757.1 - 1.6e-42 144.0 0.0 1.1e-41 141.3 0.0 2.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.1 EMR72757.1 - 2.5e-37 128.0 0.1 1.2e-35 122.5 0.0 3.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.1 EMR72757.1 - 9.5e-28 95.9 0.3 6.1e-26 90.1 0.1 3.4 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EMR72757.1 - 6.4e-09 35.4 4.2 1.6e-08 34.1 2.9 1.7 1 0 0 1 1 1 1 Hr1 repeat HEAT_2 PF13646.1 EMR72757.1 - 0.0054 16.9 4.2 2.1 8.7 0.0 4.0 3 1 0 3 3 3 2 HEAT repeats Uds1 PF15456.1 EMR72757.1 - 1.9 8.4 8.6 0.34 10.9 2.2 2.4 2 0 0 2 2 2 0 Up-regulated During Septation DEAD PF00270.24 EMR72758.1 - 1.9e-45 154.3 0.0 1.8e-44 151.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EMR72758.1 - 2.9e-05 23.9 0.0 0.0001 22.1 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2443 PF10398.4 EMR72758.1 - 0.1 12.3 0.3 0.25 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) AAA_22 PF13401.1 EMR72758.1 - 0.14 12.2 0.8 6.1 6.9 0.2 2.8 1 1 0 2 2 2 0 AAA domain TPR_11 PF13414.1 EMR72759.1 - 4.8e-16 58.1 4.0 4.6e-11 42.1 0.0 3.2 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EMR72759.1 - 3.3e-15 54.9 5.2 1.2e-07 30.9 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EMR72759.1 - 1.5e-13 49.5 5.2 2.5e-05 23.8 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EMR72759.1 - 1.3e-10 40.2 1.9 0.00017 21.1 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.19 EMR72759.1 - 2.2e-09 36.8 0.1 3.8e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.1 EMR72759.1 - 1.5e-08 34.4 0.3 0.0001 22.1 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EMR72759.1 - 7e-08 31.7 0.2 4.6e-06 26.0 0.0 3.1 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EMR72759.1 - 1.8e-06 28.0 3.2 1.6 9.3 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EMR72759.1 - 5.3e-06 26.2 0.8 0.032 14.4 0.1 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EMR72759.1 - 0.00094 19.7 0.3 0.041 14.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EMR72759.1 - 0.0013 18.5 0.1 2 8.2 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EMR72759.1 - 0.0036 17.7 0.1 0.099 13.3 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EMR72759.1 - 0.064 13.4 1.7 0.33 11.1 0.0 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 EMR72759.1 - 0.066 13.0 0.4 0.52 10.2 0.0 2.7 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.9 EMR72759.1 - 0.093 13.2 0.3 36 5.1 0.0 3.5 3 1 0 3 3 2 0 Tetratricopeptide repeat Ribosomal_L13 PF00572.13 EMR72760.1 - 9.8e-39 132.3 0.0 1.3e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.13 EMR72761.1 - 1.2e-80 268.4 0.2 3e-43 147.2 0.1 2.0 2 0 0 2 2 2 2 Uricase Polysacc_lyase PF14099.1 EMR72764.1 - 8.4e-38 130.2 8.1 9.7e-38 130.0 5.6 1.0 1 0 0 1 1 1 1 Polysaccharide lyase phage_tail_N PF08400.5 EMR72765.1 - 0.07 12.8 0.5 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Skp1 PF01466.14 EMR72765.1 - 0.1 12.6 3.1 0.22 11.5 2.1 1.6 1 0 0 1 1 1 0 Skp1 family, dimerisation domain Fungal_trans PF04082.13 EMR72766.1 - 2.9e-31 108.2 0.0 4.8e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SRP-alpha_N PF04086.8 EMR72766.1 - 0.018 14.4 0.2 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MARVEL PF01284.18 EMR72768.1 - 9.1e-05 22.3 10.3 0.00018 21.3 7.1 1.5 1 1 0 1 1 1 1 Membrane-associating domain Peptidase_M41 PF01434.13 EMR72769.1 - 4.2e-70 235.5 0.0 6.3e-70 234.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EMR72769.1 - 1.5e-42 144.9 0.0 4e-42 143.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EMR72769.1 - 4.5e-11 42.8 0.0 1.6e-10 41.0 0.0 2.0 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 EMR72769.1 - 0.00097 18.8 0.0 0.0036 17.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EMR72769.1 - 0.0011 19.0 0.9 0.071 13.2 0.1 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EMR72769.1 - 0.0029 16.7 0.0 0.0063 15.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EMR72769.1 - 0.0049 15.6 0.0 0.0089 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 EMR72769.1 - 0.0057 16.5 0.0 0.088 12.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EMR72769.1 - 0.0078 17.0 0.0 0.035 14.9 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EMR72769.1 - 0.0094 15.6 0.4 0.036 13.8 0.3 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 EMR72769.1 - 0.014 15.3 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF1958 PF09211.5 EMR72769.1 - 0.022 14.8 0.1 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1958) IstB_IS21 PF01695.12 EMR72769.1 - 0.024 14.0 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EMR72769.1 - 0.026 14.4 0.2 0.37 10.7 0.1 2.7 1 1 1 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EMR72769.1 - 0.044 12.8 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 EMR72769.1 - 0.051 12.7 0.3 0.097 11.8 0.2 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EMR72769.1 - 0.055 12.8 0.2 0.055 12.8 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EMR72769.1 - 0.12 12.2 0.9 0.2 11.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 EMR72769.1 - 0.15 12.0 0.1 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain IGPD PF00475.13 EMR72771.1 - 7.2e-61 204.2 0.3 1.1e-60 203.7 0.2 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase PGA2 PF07543.7 EMR72772.1 - 1.2e-41 141.7 3.1 1.4e-41 141.5 2.1 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 Presenilin PF01080.12 EMR72772.1 - 0.036 12.8 1.8 0.045 12.5 1.3 1.1 1 0 0 1 1 1 0 Presenilin RGS-like PF09128.6 EMR72772.1 - 0.06 12.8 1.4 0.079 12.4 1.0 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain CDC27 PF09507.5 EMR72772.1 - 0.64 9.1 8.3 0.85 8.7 5.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2514 PF10721.4 EMR72772.1 - 0.79 9.4 10.1 1.2 8.7 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Drc1-Sld2 PF11719.3 EMR72772.1 - 1.3 8.0 7.2 1.7 7.6 5.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF4428 PF14471.1 EMR72773.1 - 0.015 15.0 0.0 6.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) DUF3133 PF11331.3 EMR72773.1 - 0.023 14.2 4.5 0.14 11.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) ZZ PF00569.12 EMR72773.1 - 0.4 10.2 4.0 1.8 8.1 0.3 2.7 3 0 0 3 3 3 0 Zinc finger, ZZ type DUF3039 PF11238.3 EMR72773.1 - 2.8 7.4 6.9 37 3.8 0.2 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3039) SAP PF02037.22 EMR72775.1 - 7.7e-14 50.8 0.1 1.4e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 SAP domain CDC27 PF09507.5 EMR72775.1 - 0.13 11.4 22.6 0.16 11.1 15.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ASFV_J13L PF05568.6 EMR72775.1 - 0.23 10.9 6.2 0.37 10.2 4.3 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein IER PF05760.7 EMR72775.1 - 0.42 10.5 11.4 0.54 10.1 7.9 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) DAO PF01266.19 EMR72776.1 - 9.7e-48 162.8 11.6 4.1e-47 160.8 8.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Sporozoite_P67 PF05642.6 EMR72776.1 - 0.00081 17.3 3.6 0.00081 17.3 2.5 1.3 2 0 0 2 2 2 1 Sporozoite P67 surface antigen NAD_binding_8 PF13450.1 EMR72776.1 - 0.011 15.7 0.5 0.043 13.8 0.3 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMR72776.1 - 0.11 12.9 0.0 5.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cytochrom_C1 PF02167.10 EMR72776.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C1 family Cytochrom_C PF00034.16 EMR72776.1 - 0.13 13.0 2.0 0.49 11.2 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c Pyridoxal_deC PF00282.14 EMR72778.1 - 1.2e-39 135.8 0.0 3.9e-27 94.6 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Hus1 PF04005.7 EMR72779.1 - 1.4e-84 283.5 0.0 1.6e-84 283.3 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein DAO PF01266.19 EMR72781.1 - 5.6e-45 153.7 0.0 6.8e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EMR72781.1 - 8.4e-05 22.5 0.0 0.042 13.7 0.0 2.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR72781.1 - 0.00019 21.2 0.2 0.00099 18.9 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EMR72781.1 - 0.00028 20.8 0.0 0.00097 19.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR72781.1 - 0.01 15.8 0.0 0.057 13.4 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR72781.1 - 0.014 14.2 0.2 0.026 13.3 0.1 1.5 1 1 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.1 EMR72781.1 - 0.041 12.7 0.1 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EMR72781.1 - 0.072 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 EMR72781.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 EMR72781.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FH2 PF02181.18 EMR72782.1 - 3.9e-82 276.0 4.9 8.1e-82 275.0 3.4 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EMR72782.1 - 4.4e-63 212.0 0.1 4.4e-63 212.0 0.1 2.4 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EMR72782.1 - 2e-52 177.4 2.1 2e-52 177.4 1.4 2.9 2 1 1 3 3 3 1 Diaphanous FH3 Domain Zn_clus PF00172.13 EMR72783.1 - 0.048 13.5 10.5 0.083 12.8 7.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec16_C PF12931.2 EMR72784.1 - 1.7e-73 247.8 0.2 1.1e-49 169.6 0.0 2.1 1 1 1 2 2 2 2 Sec23-binding domain of Sec16 MFS_1 PF07690.11 EMR72785.1 - 6.4e-31 107.3 48.3 6.4e-31 107.3 33.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily RPE65 PF03055.10 EMR72786.1 - 4e-75 253.2 0.1 4.6e-58 196.9 0.0 2.0 2 0 0 2 2 2 2 Retinal pigment epithelial membrane protein HHH_5 PF14520.1 EMR72787.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain GSHPx PF00255.14 EMR72788.1 - 8.9e-40 134.4 0.1 1.1e-39 134.0 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase DUF4174 PF13778.1 EMR72788.1 - 0.00032 20.7 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) AhpC-TSA PF00578.16 EMR72788.1 - 0.0041 16.8 0.1 0.0062 16.2 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Tenui_NS4 PF03300.8 EMR72788.1 - 0.086 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Tenuivirus non-structural protein NS4 Redoxin PF08534.5 EMR72788.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 Redoxin Sec16_N PF12935.2 EMR72789.1 - 2.6e-09 37.3 20.5 2.6e-09 37.3 14.2 2.8 2 2 0 2 2 2 1 Vesicle coat trafficking protein Sec16 N-terminus LLC1 PF14945.1 EMR72789.1 - 5.1 7.4 6.2 4.7 7.5 0.1 3.1 1 1 2 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein MUG113 PF13455.1 EMR72790.1 - 2e-28 98.6 0.5 5.7e-28 97.1 0.0 2.0 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EMR72790.1 - 1.2e-20 73.7 0.7 3.5e-20 72.2 0.0 2.1 3 0 0 3 3 3 1 T5orf172 domain zf-RING_2 PF13639.1 EMR72792.1 - 5.8e-09 35.6 4.6 9.3e-09 34.9 3.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EMR72792.1 - 1.1e-05 24.9 0.1 2.7e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EMR72792.1 - 0.00013 21.9 4.2 0.00044 20.2 2.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EMR72792.1 - 0.0036 16.9 4.0 0.015 14.9 2.6 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EMR72792.1 - 0.0044 17.1 4.0 0.012 15.6 2.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EMR72792.1 - 0.0052 16.4 2.1 0.013 15.1 1.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 EMR72792.1 - 0.01 15.7 4.5 0.051 13.5 3.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Nucleoplasmin PF03066.10 EMR72792.1 - 0.12 11.8 3.0 0.19 11.2 2.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin BAF1_ABF1 PF04684.8 EMR72792.1 - 0.12 11.1 10.3 0.17 10.6 7.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CENP-B_dimeris PF09026.5 EMR72792.1 - 1.1 9.4 8.8 0.35 11.1 4.1 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zf-C3HC4_4 PF15227.1 EMR72792.1 - 2.3 8.1 10.1 2 8.3 2.3 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Menin PF05053.8 EMR72792.1 - 2.7 6.0 7.2 3.1 5.8 5.0 1.1 1 0 0 1 1 1 0 Menin Hid1 PF12722.2 EMR72792.1 - 2.9 5.4 7.4 3.3 5.2 5.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-RING_UBOX PF13445.1 EMR72792.1 - 4.3 7.1 9.0 4.3 7.1 1.3 3.0 2 1 0 2 2 2 0 RING-type zinc-finger DUF4611 PF15387.1 EMR72792.1 - 6.2 7.0 8.4 8.3 6.6 4.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Glyco_hydro_76 PF03663.9 EMR72793.1 - 1.3e-52 179.4 7.4 1.6e-52 179.1 5.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 RNase_H PF00075.19 EMR72794.1 - 2.3e-12 47.3 0.1 2e-06 28.1 0.1 2.2 1 1 1 2 2 2 2 RNase H CorA PF01544.13 EMR72795.1 - 0.0035 16.4 1.4 0.017 14.1 0.2 2.4 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein CENP-B_dimeris PF09026.5 EMR72795.1 - 0.023 14.9 0.4 0.023 14.9 0.3 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Asp PF00026.18 EMR72796.1 - 1.8e-32 112.8 0.2 2.3e-32 112.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EMR72796.1 - 3.4e-05 23.8 0.1 6.5e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Fungal_trans PF04082.13 EMR72797.1 - 5.3e-11 41.8 0.1 5.3e-11 41.8 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EMR72798.1 - 6.7e-82 275.4 21.2 7.7e-82 275.2 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EMR72798.1 - 2.7e-16 59.2 43.2 1.1e-15 57.2 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EMR72798.1 - 0.058 11.7 24.4 0.018 13.4 4.9 3.5 3 1 1 4 4 4 0 MFS/sugar transport protein MFS_1 PF07690.11 EMR72799.1 - 1.4e-14 53.5 3.8 1.4e-14 53.5 2.6 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EMR72799.1 - 2.6e-06 26.8 1.8 8.1e-06 25.2 1.3 1.8 1 0 0 1 1 1 1 Nodulin-like Nucleo_P87 PF07267.6 EMR72799.1 - 0.13 10.9 0.8 0.2 10.3 0.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 UPF0560 PF10577.4 EMR72799.1 - 0.43 8.7 5.9 0.64 8.2 4.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MRC1 PF09444.5 EMR72799.1 - 2.9 8.1 12.9 1.5 9.1 3.5 2.3 2 0 0 2 2 2 0 MRC1-like domain Thr_synth_N PF14821.1 EMR72800.1 - 2.3e-28 97.9 0.0 6.5e-28 96.5 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EMR72800.1 - 1.6e-19 70.2 0.0 9e-19 67.8 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.11 EMR72801.1 - 1.9e-23 82.7 34.8 1.1e-22 80.2 24.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily COesterase PF00135.23 EMR72802.1 - 8.2e-89 298.7 0.0 1.1e-88 298.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR72802.1 - 0.0021 17.6 0.0 0.0049 16.4 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EMR72803.1 - 1.1e-93 314.8 0.0 1.2e-93 314.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EMR72803.1 - 0.00013 21.6 0.1 0.00066 19.3 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3446 PF11928.3 EMR72804.1 - 7.3 6.8 8.0 63 3.8 5.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3446) FMO-like PF00743.14 EMR72805.1 - 2.7e-39 134.8 0.0 2.8e-23 81.9 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EMR72805.1 - 6e-18 65.6 0.0 2.4e-17 63.7 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EMR72805.1 - 1.7e-12 47.6 0.0 3e-11 43.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EMR72805.1 - 6e-10 39.1 0.0 1e-08 35.0 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EMR72805.1 - 6.3e-08 31.9 0.4 1.6e-06 27.3 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EMR72805.1 - 4.4e-06 25.9 0.0 0.00082 18.5 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 EMR72805.1 - 1.4e-05 25.0 0.0 3.6e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EMR72805.1 - 0.0029 17.9 0.3 6.3 7.2 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EMR72805.1 - 0.0037 16.2 0.0 2.6 6.8 0.0 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EMR72805.1 - 0.048 12.1 0.3 0.29 9.5 0.1 2.2 3 0 0 3 3 3 0 HI0933-like protein TEX12 PF15219.1 EMR72805.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Testis-expressed 12 DUF4381 PF14316.1 EMR72807.1 - 0.018 15.1 0.2 0.034 14.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SKG6 PF08693.5 EMR72807.1 - 0.28 10.5 1.6 0.9 8.9 1.1 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Spore_YtfJ PF09579.5 EMR72807.1 - 6.6 6.6 0.0 6.6 6.6 0.0 4.9 6 0 0 6 6 6 0 Sporulation protein YtfJ (Spore_YtfJ) TPP_enzyme_N PF02776.13 EMR72808.1 - 5.4e-25 87.8 0.1 1.7e-24 86.2 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EMR72808.1 - 5.1e-18 65.1 0.0 3.1e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EMR72808.1 - 9.9e-15 54.4 0.0 8.6e-14 51.4 0.0 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain U3_assoc_6 PF08640.6 EMR72809.1 - 3.5e-23 81.1 0.0 7.5e-23 80.0 0.0 1.6 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 EMR72809.1 - 0.00085 18.2 0.5 0.0023 16.8 0.2 1.9 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EMR72809.1 - 0.0035 17.8 0.4 15 6.5 0.0 4.7 4 1 2 6 6 6 1 Tetratricopeptide repeat Cellulase PF00150.13 EMR72810.1 - 9.9e-15 54.4 0.0 2.5e-14 53.1 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_76 PF03663.9 EMR72811.1 - 1.8e-43 149.3 5.7 4.9e-27 95.2 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 76 DUF1680 PF07944.7 EMR72811.1 - 9e-05 20.9 0.1 0.016 13.4 0.0 2.2 2 1 1 3 3 3 2 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_88 PF07470.8 EMR72811.1 - 0.0019 17.2 0.2 0.015 14.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 EVE PF01878.13 EMR72812.1 - 2.3e-49 167.1 0.1 2.3e-49 167.1 0.0 1.8 2 0 0 2 2 2 1 EVE domain Suf PF05843.9 EMR72812.1 - 0.075 12.7 4.5 0.075 12.7 2.5 1.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RNA_pol_Rbc25 PF08292.7 EMR72812.1 - 0.24 11.5 2.6 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 CI-B14_5a PF07347.7 EMR72812.1 - 1.1 9.0 8.3 2.9 7.7 1.7 3.2 2 1 1 3 3 3 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Presenilin PF01080.12 EMR72812.1 - 1.3 7.7 5.7 1.6 7.4 4.0 1.1 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.11 EMR72812.1 - 8.6 5.6 7.5 14 4.9 5.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 MFS_1 PF07690.11 EMR72815.1 - 1.3e-50 172.0 61.1 1.8e-44 151.9 29.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EMR72815.1 - 4.1e-19 68.2 9.4 7.6e-19 67.3 6.5 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4066 PF13278.1 EMR72816.1 - 3.9e-16 58.7 0.0 5e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EMR72816.1 - 3.9e-05 23.1 0.0 5.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Herpes_gE PF02480.11 EMR72817.1 - 0.032 12.5 0.0 0.037 12.3 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CD34_antigen PF06365.7 EMR72817.1 - 0.035 13.7 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF1191 PF06697.7 EMR72817.1 - 0.045 12.5 0.0 0.047 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Sarcoglycan_2 PF05510.8 EMR72817.1 - 0.049 11.9 0.0 0.055 11.7 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon TMEM154 PF15102.1 EMR72817.1 - 0.063 12.9 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Acetyltransf_1 PF00583.19 EMR72819.1 - 0.0001 22.2 0.2 0.00019 21.4 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EMR72819.1 - 0.0075 16.3 0.0 0.4 10.8 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EMR72819.1 - 0.047 13.8 0.0 0.078 13.1 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain p450 PF00067.17 EMR72820.1 - 6.5e-55 186.4 0.0 1e-54 185.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4521 PF15021.1 EMR72820.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) Ribosomal_S10 PF00338.17 EMR72822.1 - 1.9e-27 94.9 0.4 2.3e-27 94.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF4469 PF14734.1 EMR72822.1 - 0.054 13.3 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold Exo_endo_phos PF03372.18 EMR72823.1 - 9.9e-06 25.6 0.5 4.9e-05 23.3 0.0 1.9 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family p450 PF00067.17 EMR72824.1 - 1.4e-39 135.9 0.0 4.4e-27 94.7 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 CUE PF02845.11 EMR72825.1 - 4.9e-08 32.2 0.2 8.9e-08 31.4 0.1 1.4 1 0 0 1 1 1 1 CUE domain SEP PF08059.8 EMR72825.1 - 0.018 15.3 0.2 2.7 8.3 0.0 2.5 2 0 0 2 2 2 0 SEP domain DUF2454 PF10521.4 EMR72825.1 - 0.17 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) AA_permease PF00324.16 EMR72826.1 - 2.3e-134 448.3 44.2 6.1e-134 446.9 30.7 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EMR72826.1 - 9.3e-37 126.5 39.7 1.3e-36 126.0 27.5 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 EMR72826.1 - 0.077 11.4 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) BNR PF02012.15 EMR72828.1 - 6.4e-08 31.2 51.9 0.24 11.3 0.2 12.9 13 0 0 13 13 13 7 BNR/Asp-box repeat BNR_2 PF13088.1 EMR72828.1 - 1.2e-07 31.3 9.6 1 8.5 0.0 6.7 6 2 0 7 7 7 5 BNR repeat-like domain DUF2561 PF10812.3 EMR72828.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Glyco_hydro_47 PF01532.15 EMR72829.1 - 5.7e-166 552.6 0.3 6.8e-166 552.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ABC_membrane_2 PF06472.10 EMR72830.1 - 3.1e-68 229.9 3.2 3.5e-43 147.7 0.0 3.1 2 1 1 3 3 3 2 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EMR72830.1 - 6.2e-18 65.4 0.0 1.2e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EMR72830.1 - 0.00075 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EMR72830.1 - 0.0088 16.0 0.1 0.032 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EMR72830.1 - 0.03 13.8 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EMR72830.1 - 0.061 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EMR72830.1 - 0.077 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain SCAMP PF04144.8 EMR72830.1 - 0.089 12.6 0.6 0.21 11.4 0.1 1.8 2 0 0 2 2 2 0 SCAMP family SMC_N PF02463.14 EMR72830.1 - 0.093 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.16 EMR72830.1 - 0.14 11.2 0.1 0.35 9.9 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Amidohydro_1 PF01979.15 EMR72831.1 - 6.8e-44 150.8 0.4 8.1e-44 150.6 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EMR72831.1 - 3.6e-19 69.8 0.0 1.6e-18 67.7 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EMR72831.1 - 3.4e-11 42.7 0.0 2.8e-10 39.8 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EMR72831.1 - 3.5e-11 42.9 1.3 1.9e-09 37.2 0.0 2.7 2 1 0 3 3 3 1 Amidohydrolase family TPR_12 PF13424.1 EMR72832.1 - 0.0035 17.2 0.0 0.069 13.0 0.0 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat FAD_binding_3 PF01494.14 EMR72833.1 - 3.9e-29 101.8 0.2 2e-19 69.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EMR72833.1 - 1.2e-10 40.8 0.1 6.5e-06 25.2 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EMR72833.1 - 1.9e-06 27.7 0.0 4.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EMR72833.1 - 5.1e-06 26.7 0.1 3.9e-05 23.8 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EMR72833.1 - 5.2e-06 26.7 0.6 8.3e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EMR72833.1 - 8.3e-06 25.0 0.1 6.8e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 EMR72833.1 - 1e-05 24.6 0.4 0.013 14.4 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 EMR72833.1 - 1.7e-05 23.5 0.0 0.0057 15.1 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Trp_halogenase PF04820.9 EMR72833.1 - 2e-05 23.4 0.2 3.8e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.2 EMR72833.1 - 2.1e-05 23.7 0.0 7.3e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EMR72833.1 - 4.5e-05 22.7 0.1 0.031 13.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EMR72833.1 - 0.00026 20.9 0.1 0.00044 20.2 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EMR72833.1 - 0.0018 17.2 1.1 0.0028 16.5 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 EMR72833.1 - 0.013 15.0 0.1 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EMR72833.1 - 0.021 13.6 0.2 0.095 11.5 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.13 EMR72833.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 EMR72833.1 - 0.091 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EMR72833.1 - 0.1 12.3 0.5 3.1 7.5 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding zf-CSL PF05207.8 EMR72834.1 - 2e-24 84.8 1.3 2.5e-24 84.5 0.9 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EMR72834.1 - 0.054 13.4 0.2 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DUF1212 PF06738.7 EMR72835.1 - 3.4e-51 173.4 14.8 2.4e-47 160.9 0.0 2.9 3 1 1 4 4 4 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EMR72835.1 - 1.2e-28 99.6 12.7 1.2e-28 99.6 8.8 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) adh_short PF00106.20 EMR72836.1 - 6.8e-21 74.8 6.1 2.3e-20 73.1 4.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR72836.1 - 1.4e-11 44.3 0.4 2e-11 43.9 0.3 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EMR72836.1 - 7.7e-09 35.6 0.1 1.3e-08 34.9 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EMR72836.1 - 2.4e-05 23.8 0.5 6e-05 22.5 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EMR72836.1 - 0.0014 18.6 2.2 0.0077 16.2 1.5 1.9 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EMR72836.1 - 0.082 12.7 0.5 0.18 11.5 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MFS_1 PF07690.11 EMR72837.1 - 2.5e-17 62.6 24.7 1e-07 30.9 0.3 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PLDc_N PF13396.1 EMR72837.1 - 0.02 14.5 0.9 0.02 14.5 0.6 2.4 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal RNase_H PF00075.19 EMR72838.1 - 4.9e-10 39.8 0.1 8.3e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EMR72838.1 - 0.00027 20.6 0.9 0.015 15.0 0.3 2.7 2 1 0 2 2 2 1 Reverse transcriptase-like G-gamma PF00631.17 EMR72838.1 - 0.051 13.3 0.1 0.095 12.4 0.1 1.4 1 0 0 1 1 1 0 GGL domain Perilipin PF03036.11 EMR72839.1 - 0.014 14.2 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Perilipin family DUF4443 PF14544.1 EMR72839.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) Med29 PF11568.3 EMR72840.1 - 0.005 16.9 0.0 0.025 14.6 0.0 2.0 2 0 0 2 2 2 1 Mediator complex subunit 29 Coprogen_oxidas PF01218.13 EMR72841.1 - 5.5e-133 442.0 0.1 6.3e-133 441.8 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase N2227 PF07942.7 EMR72842.1 - 6e-55 186.0 0.0 1.1e-54 185.1 0.0 1.5 1 1 0 1 1 1 1 N2227-like protein Methyltransf_18 PF12847.2 EMR72842.1 - 0.00018 22.0 0.0 0.00082 19.9 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EMR72842.1 - 0.00075 19.9 0.0 0.0034 17.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EMR72842.1 - 0.0017 18.7 0.0 0.023 15.1 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EMR72842.1 - 0.0039 16.9 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EMR72842.1 - 0.024 14.6 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NFRKB_winged PF14465.1 EMR72842.1 - 0.024 14.4 0.1 0.35 10.7 0.0 2.6 3 0 0 3 3 3 0 NFRKB Winged Helix-like Methyltransf_31 PF13847.1 EMR72842.1 - 0.068 12.7 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain V_ATPase_I PF01496.14 EMR72843.1 - 0.34 8.7 10.3 0.49 8.1 7.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bacteriocin_IIc PF10439.4 EMR72843.1 - 0.35 11.0 8.1 0.65 10.1 5.6 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF981 PF06168.6 EMR72844.1 - 0.01 15.6 1.3 0.012 15.4 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF981) Glyoxalase_2 PF12681.2 EMR72845.1 - 1.3e-05 25.7 0.3 1.9e-05 25.2 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EMR72845.1 - 0.0059 16.5 0.1 0.024 14.6 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Kinesin PF00225.18 EMR72846.1 - 3.8e-68 229.6 1.3 3.8e-68 229.6 0.9 1.7 2 0 0 2 2 2 1 Kinesin motor domain Spore_coat_CotO PF14153.1 EMR72846.1 - 0.3 10.4 10.3 0.26 10.6 5.8 1.9 2 0 0 2 2 2 0 Spore coat protein CotO DUF4407 PF14362.1 EMR72846.1 - 0.78 8.6 6.6 1.3 7.9 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1840 PF08895.6 EMR72846.1 - 2.4 8.2 8.3 0.68 9.9 2.6 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) p450 PF00067.17 EMR72847.1 - 1e-70 238.5 0.0 1.2e-70 238.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3074 PF11274.3 EMR72848.1 - 4e-34 117.8 0.0 5.7e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) tRNA-synt_1 PF00133.17 EMR72849.1 - 2.4e-221 735.8 2.5 1.9e-220 732.9 1.7 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EMR72849.1 - 1.4e-31 109.2 0.8 4e-31 107.8 0.6 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EMR72849.1 - 2.8e-15 55.8 1.2 1.4e-05 23.9 0.0 4.9 3 2 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EMR72849.1 - 3.1e-11 42.9 7.5 2.1e-08 33.6 0.0 3.5 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 EMR72849.1 - 6.9e-05 22.8 2.6 6.9e-05 22.8 1.8 2.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm DUF3735 PF12537.3 EMR72849.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) Fusion_gly PF00523.13 EMR72849.1 - 0.17 9.9 0.0 0.27 9.2 0.0 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 PepSY PF03413.14 EMR72849.1 - 0.32 11.6 4.9 0.46 11.1 0.0 3.3 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Stk19 PF10494.4 EMR72850.1 - 1.5e-63 214.4 0.0 1.8e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 MarR_2 PF12802.2 EMR72850.1 - 0.013 15.1 0.1 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 MarR family LexA_DNA_bind PF01726.11 EMR72850.1 - 0.084 12.4 0.5 0.29 10.7 0.0 2.1 3 0 0 3 3 3 0 LexA DNA binding domain NodZ PF05830.6 EMR72851.1 - 0.13 10.7 0.1 12 4.3 0.0 2.2 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) WD40 PF00400.27 EMR72852.1 - 0.0027 17.5 0.4 0.42 10.5 0.0 3.6 4 1 1 5 5 5 1 WD domain, G-beta repeat Metallophos PF00149.23 EMR72853.1 - 2.6e-39 134.6 0.2 3.3e-39 134.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SUR7 PF06687.7 EMR72854.1 - 3.8e-29 101.7 12.2 4.8e-29 101.4 8.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EMR72854.1 - 0.14 11.8 16.6 0.079 12.6 6.9 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 EMR72854.1 - 0.97 8.6 7.1 0.09 12.0 1.3 1.9 2 0 0 2 2 2 0 Clc-like WD40 PF00400.27 EMR72855.1 - 1.5e-09 37.3 0.4 0.057 13.3 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Myc_N PF01056.13 EMR72855.1 - 0.085 12.0 1.4 0.15 11.2 1.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region NAD_binding_4 PF07993.7 EMR72857.1 - 1e-32 113.0 0.0 1.5e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EMR72857.1 - 6.1e-11 42.2 0.0 1.1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EMR72857.1 - 1e-07 32.1 0.0 2.9e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.23 EMR72857.1 - 2.3e-07 29.5 0.0 4.1e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme 3Beta_HSD PF01073.14 EMR72857.1 - 1.1e-05 24.2 0.0 7.8e-05 21.5 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EMR72857.1 - 0.0033 17.7 0.0 0.0085 16.3 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EMR72857.1 - 0.0074 16.3 0.1 0.13 12.2 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding P2X_receptor PF00864.14 EMR72857.1 - 0.15 10.7 0.0 0.6 8.7 0.0 1.8 2 0 0 2 2 2 0 ATP P2X receptor p450 PF00067.17 EMR72858.1 - 3.6e-22 78.5 0.0 4.1e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CCT_2 PF09425.5 EMR72858.1 - 0.34 10.4 3.3 1.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Divergent CCT motif F-box-like PF12937.2 EMR72859.1 - 0.00045 19.8 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EMR72859.1 - 0.015 14.9 0.0 0.051 13.2 0.0 1.9 1 0 0 1 1 1 0 F-box-like domain F-box PF00646.28 EMR72859.1 - 0.1 12.2 1.5 6.9 6.4 0.2 2.9 2 0 0 2 2 2 0 F-box domain CPSase_L_D2 PF02786.12 EMR72860.1 - 8.9e-70 234.2 0.0 1.3e-69 233.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EMR72860.1 - 5.6e-35 119.5 0.0 1.4e-34 118.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EMR72860.1 - 9.3e-32 109.4 0.0 1.8e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_lipoyl PF00364.17 EMR72860.1 - 4.7e-17 61.3 1.8 1.5e-16 59.8 1.3 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EMR72860.1 - 3.2e-16 59.5 0.0 5.9e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EMR72860.1 - 1.3e-11 43.8 0.0 2e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EMR72860.1 - 7.7e-09 35.0 0.5 0.0026 17.3 0.0 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EMR72860.1 - 6.7e-06 25.6 0.0 1.8e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EMR72860.1 - 1.5e-05 24.3 0.0 2.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 EMR72860.1 - 2e-05 24.0 0.1 0.023 14.0 0.0 2.5 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_2 PF12700.2 EMR72860.1 - 0.003 16.7 0.1 0.53 9.3 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 EMR72860.1 - 0.016 15.5 0.1 8.4 6.7 0.0 2.9 3 0 0 3 3 2 0 HlyD family secretion protein Nairovirus_M PF07948.6 EMR72860.1 - 0.04 12.0 0.0 0.056 11.5 0.0 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like RimK PF08443.6 EMR72860.1 - 0.043 13.3 0.0 0.79 9.1 0.0 2.4 3 0 0 3 3 3 0 RimK-like ATP-grasp domain FBPase PF00316.15 EMR72860.1 - 0.14 10.9 0.1 0.73 8.5 0.0 1.9 2 0 0 2 2 2 0 Fructose-1-6-bisphosphatase Pyridox_oxidase PF01243.15 EMR72861.1 - 7.9e-14 51.4 0.0 9.5e-13 47.9 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EMR72861.1 - 0.00062 19.6 0.0 0.013 15.2 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.9 EMR72861.1 - 0.0022 16.0 0.0 0.0026 15.8 0.0 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Ribosomal_S16 PF00886.14 EMR72862.1 - 1.9e-25 88.3 0.3 3.7e-25 87.3 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S16 p450 PF00067.17 EMR72863.1 - 8.1e-39 133.4 0.1 9.9e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AJAP1_PANP_C PF15298.1 EMR72864.1 - 0.00028 20.8 0.1 0.00036 20.4 0.0 1.2 1 0 0 1 1 1 1 AJAP1/PANP C-terminus DUF3357 PF11837.3 EMR72864.1 - 0.0017 18.1 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) DUF1049 PF06305.6 EMR72864.1 - 0.0064 15.9 0.3 0.013 14.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1049) Myc_target_1 PF15179.1 EMR72864.1 - 0.035 13.6 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Myc target protein 1 EphA2_TM PF14575.1 EMR72864.1 - 0.052 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3481 PF11980.3 EMR72864.1 - 0.053 13.3 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) Aldo_ket_red PF00248.16 EMR72865.1 - 1.4e-67 227.5 0.0 1.6e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family B12-binding PF02310.14 EMR72865.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain UbiA PF01040.13 EMR72866.1 - 2.4e-20 72.8 9.9 3.3e-20 72.3 6.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Erv26 PF04148.8 EMR72866.1 - 0.036 13.4 0.3 0.075 12.3 0.2 1.5 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 Cyclin_C PF02984.14 EMR72867.1 - 0.15 11.9 0.4 18 5.2 0.1 2.4 2 0 0 2 2 2 0 Cyclin, C-terminal domain DUF1471 PF07338.8 EMR72868.1 - 0.081 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) p450 PF00067.17 EMR72869.1 - 2.5e-40 138.4 0.0 3.5e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EMR72870.1 - 5.8e-23 80.9 0.6 1e-22 80.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EMR72870.1 - 0.00059 19.7 0.1 0.0024 17.7 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like HycI PF01750.13 EMR72871.1 - 0.0036 16.8 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase maturation protease BBE PF08031.7 EMR72872.1 - 0.0037 17.1 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_M10 PF00413.19 EMR72873.1 - 0.011 15.4 0.0 0.03 14.0 0.0 1.5 1 1 1 2 2 2 0 Matrixin Bile_Hydr_Trans PF04775.9 EMR72873.1 - 0.016 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region DUF3810 PF12725.2 EMR72873.1 - 0.077 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) YjeF_N PF03853.10 EMR72874.1 - 1.3e-35 122.5 0.0 1.5e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus FHA PF00498.21 EMR72875.1 - 2.3e-17 62.8 0.1 8.2e-17 61.0 0.1 2.0 1 0 0 1 1 1 1 FHA domain YlqD PF11068.3 EMR72875.1 - 0.02 14.9 11.2 0.22 11.5 1.4 2.5 2 0 0 2 2 2 0 YlqD protein Cauli_AT PF03233.8 EMR72875.1 - 0.11 12.1 1.1 0.3 10.7 0.7 1.7 1 0 0 1 1 1 0 Aphid transmission protein Cu-oxidase_3 PF07732.10 EMR72876.1 - 6.6e-45 151.6 2.1 1.5e-41 140.8 0.1 3.6 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EMR72876.1 - 7.6e-33 112.9 2.7 3.6e-28 97.7 0.3 4.1 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EMR72876.1 - 4.4e-31 107.9 0.1 9.1e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Exo_endo_phos PF03372.18 EMR72877.1 - 9.8e-12 45.3 0.2 1.7e-11 44.5 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BSP_II PF05432.6 EMR72877.1 - 7.5 5.7 11.5 2.8 7.1 0.4 2.8 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) PBP1_TM PF14812.1 EMR72877.1 - 9.3 6.6 10.1 8.8 6.7 3.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_S9 PF00380.14 EMR72878.1 - 6.7e-37 126.4 0.3 1.1e-36 125.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 EMR72881.1 - 4e-40 135.8 0.1 6.6e-40 135.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EMR72881.1 - 4.6e-15 55.3 0.1 1.4e-14 53.8 0.1 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EMR72881.1 - 4.9e-12 45.8 0.0 2e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EMR72881.1 - 2.2e-11 43.4 1.0 9.2e-11 41.4 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EMR72881.1 - 2.5e-09 37.2 0.0 5.2e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EMR72881.1 - 4.9e-06 26.9 0.1 1.3e-05 25.6 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EMR72881.1 - 2.8e-05 24.0 0.0 5.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Vfa1 PF08432.5 EMR72882.1 - 1.5e-57 194.5 22.3 1.9e-57 194.1 15.4 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 EMR72882.1 - 0.02 13.8 4.8 0.022 13.7 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MTBP_N PF14918.1 EMR72882.1 - 0.03 13.7 4.4 0.02 14.2 1.2 1.8 1 1 1 2 2 2 0 MDM2-binding CDC45 PF02724.9 EMR72882.1 - 0.058 11.4 13.0 0.066 11.2 9.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.1 EMR72882.1 - 0.12 10.8 9.9 0.15 10.5 6.9 1.1 1 0 0 1 1 1 0 Raftlin Ycf1 PF05758.7 EMR72882.1 - 0.3 8.7 14.9 0.35 8.5 10.3 1.0 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 EMR72882.1 - 0.43 9.9 22.5 0.59 9.4 15.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) UPF0560 PF10577.4 EMR72882.1 - 0.45 8.7 10.7 0.52 8.4 7.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Atrophin-1 PF03154.10 EMR72882.1 - 0.72 7.9 16.7 0.8 7.7 11.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family Borrelia_P83 PF05262.6 EMR72882.1 - 0.86 7.7 17.7 0.96 7.6 12.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein FLO_LFY PF01698.11 EMR72882.1 - 1.1 8.0 12.6 1.7 7.4 8.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein IncA PF04156.9 EMR72882.1 - 1.3 8.5 6.3 1.5 8.3 4.4 1.2 1 0 0 1 1 1 0 IncA protein U79_P34 PF03064.11 EMR72882.1 - 2.6 7.4 18.3 4.5 6.7 12.7 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Hid1 PF12722.2 EMR72882.1 - 4.4 4.8 7.8 4.5 4.8 5.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MIP-T3 PF10243.4 EMR72882.1 - 6.9 5.0 37.1 9.1 4.6 25.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NARP1 PF12569.3 EMR72882.1 - 8 5.0 21.4 9.7 4.8 14.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Lipoxygenase PF00305.14 EMR72883.1 - 1.7e-22 79.2 0.0 2.4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase Rtt106 PF08512.7 EMR72884.1 - 3.4e-24 84.6 0.0 8.4e-24 83.3 0.0 1.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like VQ PF05678.9 EMR72884.1 - 0.054 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 VQ motif HET PF06985.6 EMR72885.1 - 3.9e-34 117.8 0.0 6.8e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2638 PF10937.3 EMR72886.1 - 8.1e-34 117.0 0.8 1.1e-33 116.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) CDC37_N PF03234.9 EMR72887.1 - 0.013 15.7 1.3 0.015 15.6 0.9 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding TPR_MLP1_2 PF07926.7 EMR72887.1 - 0.044 13.5 2.4 6 6.6 1.6 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 EMR72887.1 - 0.089 11.4 6.4 0.21 10.1 4.5 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein NPV_P10 PF05531.7 EMR72887.1 - 1.6 9.0 5.9 17 5.7 2.0 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF607 PF04678.8 EMR72888.1 - 3.5e-38 131.3 0.5 2e-37 128.8 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF607 Abhydrolase_6 PF12697.2 EMR72889.1 - 1.6e-12 47.7 0.6 2.5e-12 47.1 0.3 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR72889.1 - 1.5e-06 28.0 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR72889.1 - 0.0001 21.9 0.1 0.00045 19.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold CoA_trans PF01144.18 EMR72890.1 - 3.3e-96 320.6 1.4 2.1e-58 197.0 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EMR72890.1 - 0.0034 17.0 0.1 0.0071 16.0 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain MFS_1 PF07690.11 EMR72891.1 - 9e-38 129.8 26.4 1.1e-37 129.5 18.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EMR72891.1 - 1.1e-05 24.9 1.5 3.4e-05 23.3 1.1 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.2 EMR72891.1 - 0.0039 16.9 1.6 0.025 14.3 0.9 2.5 2 0 0 2 2 2 1 MFS_1 like family Orthoreo_P10 PF07204.6 EMR72891.1 - 0.11 12.2 0.2 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 CMD PF02627.15 EMR72892.1 - 0.014 15.2 0.3 0.38 10.6 0.0 2.6 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Tet_JBP PF12851.2 EMR72894.1 - 5.4e-09 35.5 0.0 1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Abhydrolase_6 PF12697.2 EMR72895.1 - 5.1e-07 29.8 0.0 8.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AA_permease_2 PF13520.1 EMR72895.1 - 4.3e-05 22.2 11.2 4.3e-05 22.2 7.8 2.5 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 EMR72895.1 - 0.00024 19.6 21.7 0.02 13.2 1.7 3.0 1 1 2 3 3 3 3 Amino acid permease Glyco_transf_22 PF03901.12 EMR72895.1 - 0.12 11.3 2.0 0.17 10.8 1.4 1.1 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family Telomerase_RBD PF12009.3 EMR72896.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain DAO PF01266.19 EMR72897.1 - 4.3e-56 190.3 1.3 5.4e-56 190.0 0.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EMR72897.1 - 3.9e-07 30.3 0.0 0.019 15.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EMR72897.1 - 4.4e-05 23.4 0.8 0.00011 22.1 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EMR72897.1 - 0.00057 18.8 3.0 0.012 14.5 0.2 2.3 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.9 EMR72897.1 - 0.0024 17.7 0.1 0.015 15.1 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EMR72897.1 - 0.0046 15.9 0.1 0.0072 15.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein K_oxygenase PF13434.1 EMR72897.1 - 0.0051 15.7 0.0 0.018 13.9 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EMR72897.1 - 0.025 14.3 0.1 0.069 12.9 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EMR72897.1 - 0.027 13.5 0.0 0.027 13.5 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.10 EMR72897.1 - 0.049 11.8 0.0 0.076 11.1 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) GARS_N PF02844.10 EMR72897.1 - 0.17 12.3 0.4 2.4 8.7 0.1 2.2 1 1 1 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Pyr_redox PF00070.22 EMR72897.1 - 1.2 9.6 3.4 5.7 7.4 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase BUD22 PF09073.5 EMR72898.1 - 3.1 6.7 25.7 5.3 5.9 17.8 1.3 1 0 0 1 1 1 0 BUD22 Vinculin PF01044.14 EMR72899.1 - 0.0077 14.3 0.1 0.0091 14.0 0.1 1.0 1 0 0 1 1 1 1 Vinculin family Zn_clus PF00172.13 EMR72900.1 - 0.61 10.0 7.4 4.8 7.1 5.1 2.2 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2046 PF09755.4 EMR72902.1 - 0.048 12.5 0.0 0.048 12.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Striatin PF08232.7 EMR72902.1 - 4.1 7.7 8.9 0.81 10.0 0.0 3.1 3 1 0 3 3 3 0 Striatin family Cellulase PF00150.13 EMR72903.1 - 3.3e-11 42.9 0.0 9.3e-11 41.4 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Trp_DMAT PF11991.3 EMR72904.1 - 1e-54 186.1 0.0 6.5e-37 127.5 0.0 2.3 1 1 1 2 2 2 2 Tryptophan dimethylallyltransferase RRM_1 PF00076.17 EMR72906.1 - 8.9e-08 31.6 0.1 1.6e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EMR72906.1 - 2.2e-07 30.7 0.0 3.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PAP1 PF08601.5 EMR72906.1 - 0.0042 16.8 1.3 0.0064 16.2 0.9 1.3 1 0 0 1 1 1 1 Transcription factor PAP1 Nup35_RRM_2 PF14605.1 EMR72906.1 - 0.0055 16.4 0.0 0.0094 15.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MBF1 PF08523.5 EMR72906.1 - 0.025 14.5 2.2 0.063 13.3 1.5 1.7 1 0 0 1 1 1 0 Multiprotein bridging factor 1 RRM_5 PF13893.1 EMR72906.1 - 0.043 13.6 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldedh PF00171.17 EMR72907.1 - 1.6e-114 382.8 0.2 1.9e-114 382.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short_C2 PF13561.1 EMR72909.1 - 1.3e-11 44.7 0.0 1.5e-11 44.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EMR72909.1 - 7.5e-11 42.2 0.0 9.2e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EMR72909.1 - 0.00024 20.8 0.1 0.00036 20.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EMR72909.1 - 0.0027 17.4 0.2 0.0065 16.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EMR72909.1 - 0.011 15.6 0.2 0.019 14.9 0.1 1.3 1 1 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 EMR72909.1 - 0.022 13.8 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.14 EMR72909.1 - 0.031 12.9 0.0 0.039 12.6 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase HTH_40 PF14493.1 EMR72909.1 - 0.061 13.5 0.1 0.12 12.5 0.1 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain NAD_binding_7 PF13241.1 EMR72909.1 - 0.075 13.2 0.1 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 EMR72909.1 - 0.082 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Baculo_p48 PF04878.8 EMR72909.1 - 0.09 11.7 0.0 5 5.9 0.0 2.0 2 0 0 2 2 2 0 Baculovirus P48 protein Glyco_tran_WecB PF03808.8 EMR72909.1 - 0.15 11.4 0.0 1 8.7 0.0 2.0 1 1 1 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family 7kD_coat PF02495.12 EMR72909.1 - 0.54 9.7 3.4 0.65 9.4 0.5 2.1 2 0 0 2 2 2 0 7kD viral coat protein NRDE-2 PF08424.5 EMR72911.1 - 5.5e-37 127.3 0.3 1.4e-33 116.1 0.1 2.3 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EMR72911.1 - 0.00045 20.5 0.1 7.8 7.4 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Voltage_CLC PF00654.15 EMR72912.1 - 1e-85 287.9 20.5 1e-85 287.9 14.2 1.3 2 0 0 2 2 2 1 Voltage gated chloride channel TAT_signal PF10518.4 EMR72912.1 - 8 6.7 14.4 0.05 13.6 2.1 3.2 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence HeLo PF14479.1 EMR72913.1 - 1.9e-11 44.1 0.2 2.4e-11 43.8 0.2 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF4279 PF14106.1 EMR72913.1 - 0.077 12.8 0.1 0.43 10.4 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4279) Retrotrans_gag PF03732.12 EMR72913.1 - 0.087 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Glyco_hydro_16 PF00722.16 EMR72914.1 - 4.8e-19 68.3 0.3 8.5e-19 67.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RasGEF PF00617.14 EMR72915.1 - 3.5e-61 206.2 0.0 7.3e-61 205.1 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EMR72915.1 - 6.1e-27 93.7 0.3 1.8e-26 92.2 0.2 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Fungal_trans PF04082.13 EMR72916.1 - 1.2e-13 50.5 2.8 1.9e-13 49.9 1.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EMR72916.1 - 0.0098 16.1 0.9 0.039 14.2 0.7 2.1 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2 PF00096.21 EMR72916.1 - 0.12 12.7 1.6 0.33 11.3 1.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type MFS_1 PF07690.11 EMR72917.1 - 1.2e-23 83.4 29.5 7.5e-13 47.9 6.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1688 PF07958.6 EMR72918.1 - 3e-177 589.3 0.0 3.5e-177 589.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) TOM13 PF08219.6 EMR72919.1 - 1.7e-30 104.6 0.0 2.2e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 Abhydrolase_6 PF12697.2 EMR72920.1 - 7.7e-32 110.9 0.1 1.2e-31 110.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EMR72920.1 - 5.6e-14 52.1 0.0 1.5e-12 47.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EMR72920.1 - 1.2e-09 38.1 0.0 8.1e-09 35.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EMR72920.1 - 0.002 17.9 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EMR72920.1 - 0.0026 17.0 0.0 0.0061 15.8 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.15 EMR72920.1 - 0.0032 17.7 0.0 0.0047 17.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 EMR72920.1 - 0.0033 16.8 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Cellulase-like PF12876.2 EMR72920.1 - 0.038 14.4 0.0 0.35 11.3 0.0 2.4 2 0 0 2 2 2 0 Sugar-binding cellulase-like BAAT_C PF08840.6 EMR72920.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal 60KD_IMP PF02096.15 EMR72921.1 - 7.1e-28 97.6 8.7 1.1e-27 97.0 6.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Vesiculo_matrix PF06326.7 EMR72921.1 - 0.047 13.1 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Vesiculovirus matrix protein adh_short PF00106.20 EMR72922.1 - 2.2e-16 60.1 0.8 3.3e-16 59.6 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR72922.1 - 4.1e-15 56.2 0.0 4.8e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR72922.1 - 7.8e-09 35.4 0.1 1.3e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EMR72922.1 - 3.6e-06 26.5 0.0 4.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EMR72922.1 - 4.4e-05 22.7 0.0 0.0019 17.4 0.0 2.1 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EMR72922.1 - 0.0086 16.0 0.4 0.09 12.7 0.2 2.3 1 1 0 1 1 1 1 NADH(P)-binding ComA PF02679.10 EMR72923.1 - 4.1e-77 258.4 0.0 4.8e-77 258.2 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) DUF2542 PF10808.3 EMR72923.1 - 0.061 13.5 0.1 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2542) SEP PF08059.8 EMR72924.1 - 5.1e-25 87.5 0.5 1.4e-24 86.1 0.0 2.0 3 0 0 3 3 3 1 SEP domain UBA_4 PF14555.1 EMR72924.1 - 9.9e-11 41.0 1.8 1.7e-10 40.2 1.3 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EMR72924.1 - 7.9e-09 35.4 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA PF00627.26 EMR72924.1 - 0.0012 18.5 0.5 0.002 17.8 0.3 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Sld5 PF05916.6 EMR72925.1 - 4.4e-22 78.4 0.0 6.4e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein adh_short PF00106.20 EMR72927.1 - 1.8e-14 53.9 0.6 2.2e-14 53.7 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EMR72927.1 - 2.3e-09 37.3 0.0 2.6e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EMR72927.1 - 5.9e-07 29.3 0.1 7.5e-07 28.9 0.1 1.0 1 0 0 1 1 1 1 KR domain DUF3129 PF11327.3 EMR72927.1 - 0.0024 17.7 0.5 0.0029 17.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) 3HCDH_N PF02737.13 EMR72927.1 - 0.0036 16.9 0.4 0.0045 16.6 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PqqD PF05402.7 EMR72927.1 - 0.041 13.9 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Spore_IV_A PF09547.5 EMR72927.1 - 0.061 12.0 0.0 0.08 11.6 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) F420_oxidored PF03807.12 EMR72927.1 - 0.063 13.7 0.8 0.11 12.9 0.5 1.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EMR72927.1 - 0.09 12.1 0.0 0.097 12.0 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NTP_transf_3 PF12804.2 EMR72927.1 - 0.094 12.7 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 MobA-like NTP transferase domain AdoHcyase_NAD PF00670.16 EMR72927.1 - 0.41 10.4 2.1 0.58 9.9 1.4 1.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Aldo_ket_red PF00248.16 EMR72928.1 - 7.1e-50 169.4 0.0 8.4e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PAP2 PF01569.16 EMR72929.1 - 2.7e-20 72.3 0.6 6e-20 71.2 0.4 1.6 1 1 0 1 1 1 1 PAP2 superfamily DUF4389 PF14333.1 EMR72929.1 - 0.058 13.0 1.3 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) PAP2_C PF14360.1 EMR72929.1 - 5 7.4 7.2 0.49 10.7 1.4 2.0 2 0 0 2 2 2 0 PAP2 superfamily C-terminal CK_II_beta PF01214.13 EMR72930.1 - 9.8e-72 240.3 0.2 1.2e-71 240.0 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Yip1 PF04893.12 EMR72931.1 - 5.4e-13 48.8 15.0 8.7e-13 48.1 10.4 1.5 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EMR72931.1 - 0.48 10.0 12.3 8.6 5.9 9.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1282) HAD_2 PF13419.1 EMR72932.1 - 7.3e-13 49.1 0.0 9.5e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EMR72932.1 - 1.7e-08 34.0 0.0 3.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EMR72932.1 - 0.0099 16.0 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EMR72932.1 - 0.012 16.0 0.0 0.044 14.2 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EMR72933.1 - 8.2e-26 90.7 0.0 1.1e-24 86.9 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EMR72933.1 - 1.6e-10 40.4 0.0 0.0018 17.4 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 EMR72933.1 - 0.0088 15.8 0.5 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EMR72933.1 - 0.034 13.2 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.22 EMR72934.1 - 4.6e-43 146.8 0.0 1.4e-20 73.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EMR72934.1 - 2.3e-24 86.2 14.8 3.9e-23 82.2 2.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EMR72934.1 - 5.4e-09 35.5 0.6 0.16 11.1 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EMR72934.1 - 5.7e-09 36.3 4.4 0.044 13.7 0.3 4.7 3 2 0 4 4 3 3 AAA domain AAA_29 PF13555.1 EMR72934.1 - 7.8e-08 31.7 1.5 0.0054 16.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EMR72934.1 - 1.7e-07 31.3 0.5 0.015 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EMR72934.1 - 1.9e-07 31.9 0.0 0.021 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EMR72934.1 - 2.3e-07 31.0 0.0 0.04 14.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EMR72934.1 - 3.6e-06 26.9 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EMR72934.1 - 5.3e-06 25.7 0.1 0.019 14.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EMR72934.1 - 1.1e-05 25.7 0.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EMR72934.1 - 3.1e-05 24.4 0.0 0.0056 17.1 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 EMR72934.1 - 4.1e-05 22.6 0.0 0.034 13.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 EMR72934.1 - 7.5e-05 23.1 0.5 0.19 12.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EMR72934.1 - 0.00013 21.8 0.1 0.23 11.3 0.1 3.0 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 EMR72934.1 - 0.00018 21.2 0.2 0.79 9.4 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EMR72934.1 - 0.00044 20.1 1.1 0.0066 16.3 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 Dynamin_N PF00350.18 EMR72934.1 - 0.0006 19.6 0.4 0.34 10.7 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.1 EMR72934.1 - 0.00071 19.0 0.4 0.3 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EMR72934.1 - 0.0014 18.1 0.5 0.83 9.0 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain AAA PF00004.24 EMR72934.1 - 0.0019 18.4 0.0 0.49 10.5 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EMR72934.1 - 0.0024 17.0 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EMR72934.1 - 0.0036 17.0 0.7 0.33 10.7 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain Adeno_IVa2 PF02456.10 EMR72934.1 - 0.0045 15.6 0.1 1.8 7.1 0.0 2.2 2 0 0 2 2 2 2 Adenovirus IVa2 protein cobW PF02492.14 EMR72934.1 - 0.0047 16.3 0.1 2.2 7.7 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EMR72934.1 - 0.0069 15.8 0.1 0.6 9.5 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 EMR72934.1 - 0.013 14.9 0.1 0.35 10.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.16 EMR72934.1 - 0.016 14.3 0.5 2.6 7.1 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.1 EMR72934.1 - 0.017 15.0 4.7 1.2 9.1 0.3 3.6 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit GTP_EFTU PF00009.22 EMR72934.1 - 0.02 14.3 0.1 1 8.7 0.0 2.7 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain Guanylate_kin PF00625.16 EMR72934.1 - 0.023 14.1 0.0 0.07 12.5 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase PduV-EutP PF10662.4 EMR72934.1 - 0.031 13.7 0.2 0.53 9.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EMR72934.1 - 0.035 14.2 0.0 12 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.8 EMR72934.1 - 0.056 12.3 0.1 13 4.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 EMR72934.1 - 0.06 12.9 0.4 4 6.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.9 EMR72934.1 - 0.082 12.6 0.7 19 4.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EMR72934.1 - 0.082 12.5 0.0 4.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 EMR72934.1 - 0.17 11.5 0.3 2.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EMR72934.1 - 0.31 10.4 1.8 27 4.1 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_24 PF13479.1 EMR72934.1 - 0.32 10.5 0.7 15 5.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain GN3L_Grn1 PF08701.6 EMR72935.1 - 2e-26 91.6 18.4 4.8e-26 90.4 12.8 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EMR72935.1 - 8.1e-22 77.3 0.1 7.2e-15 54.9 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EMR72935.1 - 9.2e-08 32.0 5.1 0.0022 17.8 0.0 3.8 4 0 0 4 4 4 2 Dynamin family GTP_EFTU PF00009.22 EMR72935.1 - 2.2e-07 30.5 0.0 0.014 14.8 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EMR72935.1 - 0.0004 19.6 0.2 0.00066 18.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EMR72935.1 - 0.00056 19.2 0.2 0.051 12.8 0.1 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.1 EMR72935.1 - 0.018 15.0 4.1 0.035 14.0 0.2 2.8 3 0 0 3 3 3 0 AAA ATPase domain Miro PF08477.8 EMR72935.1 - 0.023 15.1 0.1 3.3 8.2 0.1 2.6 2 0 0 2 2 2 0 Miro-like protein p450 PF00067.17 EMR72936.1 - 8.4e-42 143.2 0.0 3e-36 124.9 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 EMR72937.1 - 3.9e-71 239.9 0.0 4.6e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 EMR72938.1 - 0.077 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1212 PF06738.7 EMR72939.1 - 3.9e-46 156.9 4.1 3.9e-46 156.9 2.8 3.0 3 1 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EMR72939.1 - 6.1e-25 87.6 15.5 6.1e-25 87.6 10.8 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) DHDPS PF00701.17 EMR72940.1 - 1.4e-44 151.8 0.0 1.8e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family