# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DNA_pol_phi PF04931.8 KOS16594.1 - 1.8e-45 155.0 68.1 7.5e-28 96.7 32.7 4.2 3 1 0 3 3 3 2 DNA polymerase phi TFIIE_beta PF02186.10 KOS16594.1 - 0.15 12.0 0.1 28 4.8 0.0 2.8 2 0 0 2 2 2 0 TFIIE beta subunit core domain Rhodanese PF00581.15 KOS16595.1 - 1.7e-11 44.4 0.0 3.5e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain CwfJ_C_2 PF04676.9 KOS16596.1 - 4.8e-23 81.4 0.0 8.9e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 KOS16596.1 - 4.2e-22 78.0 0.0 2.1e-21 75.8 0.0 2.0 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 Metallophos_3 PF14582.1 KOS16596.1 - 0.0091 15.1 0.0 0.031 13.4 0.0 1.8 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily DRIM PF07539.7 KOS16597.1 - 6.2e-40 135.8 0.0 1.7e-39 134.4 0.0 1.8 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 KOS16597.1 - 0.00092 19.1 16.5 11 6.4 0.0 10.0 10 1 1 11 11 11 2 HEAT repeat Arm PF00514.18 KOS16597.1 - 5.2 7.0 12.6 42 4.1 0.0 7.3 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat zf-DNL PF05180.7 KOS16598.1 - 6e-27 93.1 0.3 7.9e-27 92.7 0.2 1.1 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 KOS16598.1 - 0.0096 15.4 0.2 0.017 14.5 0.1 1.3 1 0 0 1 1 1 1 CSL zinc finger Zn_Tnp_IS1595 PF12760.2 KOS16598.1 - 9.4 6.1 7.6 61 3.5 4.8 2.4 2 1 1 3 3 3 0 Transposase zinc-ribbon domain CAP PF00188.21 KOS16599.1 - 1.9e-10 41.2 0.4 2.2e-10 41.0 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SNF5 PF04855.7 KOS16600.1 - 1.5e-84 283.2 0.0 2.1e-84 282.8 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 TAFH PF07531.9 KOS16600.1 - 0.024 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 NHR1 homology to TAF Ribosomal_60s PF00428.14 KOS16600.1 - 4.2 7.8 10.9 2.8 8.3 5.0 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein CUE PF02845.11 KOS16601.1 - 6.8e-06 25.4 0.0 1.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain Chorion_2 PF03964.10 KOS16602.1 - 0.021 15.3 2.9 0.021 15.3 2.0 2.3 2 0 0 2 2 2 0 Chorion family 2 TPR_14 PF13428.1 KOS16602.1 - 0.15 12.8 3.5 4.5 8.1 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KOS16602.1 - 1.2 9.8 9.0 1.3 9.7 3.7 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Ofd1_CTDD PF10637.4 KOS16603.1 - 4.7e-93 311.1 3.5 4.7e-88 294.7 0.0 2.6 3 0 0 3 3 3 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KOS16603.1 - 1e-14 54.8 0.1 3.2e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily BUD22 PF09073.5 KOS16603.1 - 2.8 6.8 28.7 0.55 9.2 4.1 2.3 2 0 0 2 2 2 0 BUD22 DUF1049 PF06305.6 KOS16604.1 - 0.27 10.7 1.6 1.1 8.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) FAD_binding_4 PF01565.18 KOS16605.1 - 8.4e-20 70.6 2.4 1.6e-19 69.7 1.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KOS16605.1 - 0.00029 20.6 0.1 0.0011 18.8 0.1 2.0 2 0 0 2 2 2 1 Berberine and berberine like PCI PF01399.22 KOS16606.1 - 3.2e-19 69.1 0.1 1e-18 67.5 0.0 1.9 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KOS16606.1 - 5.9e-07 29.3 0.0 1.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 KOS16606.1 - 0.0035 17.0 0.5 0.33 10.8 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF4423 PF14394.1 KOS16606.1 - 0.0092 15.5 0.1 0.15 11.5 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4423) TPR_10 PF13374.1 KOS16606.1 - 0.02 14.8 0.0 1.2 9.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KOS16606.1 - 0.024 14.4 0.2 0.024 14.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Ipi1_N PF12333.3 KOS16606.1 - 0.045 13.7 0.2 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation FeoC PF09012.5 KOS16606.1 - 0.052 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator TPR_2 PF07719.12 KOS16606.1 - 0.066 13.1 0.1 0.066 13.1 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KOS16606.1 - 0.068 12.8 1.1 0.94 9.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KOS16606.1 - 0.12 13.1 0.6 3.2 8.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KOS16606.1 - 0.28 11.1 5.0 1.7 8.6 0.0 3.6 2 2 1 4 4 4 0 Tetratricopeptide repeat Peptidase_C65 PF10275.4 KOS16607.1 - 2.2e-60 204.0 0.0 2.8e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Zip PF02535.17 KOS16607.1 - 0.0018 17.3 0.1 0.0024 16.9 0.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter MotB_plug PF13677.1 KOS16607.1 - 0.019 14.2 0.5 0.039 13.2 0.4 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Gln-synt_C PF00120.19 KOS16608.1 - 4.2e-63 212.9 0.0 5.5e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Methyltransf_23 PF13489.1 KOS16609.1 - 7.2e-14 51.8 0.0 1.5e-13 50.7 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS16609.1 - 2e-09 38.0 0.0 9.9e-09 35.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS16609.1 - 7.6e-08 32.7 0.0 2.2e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KOS16609.1 - 1.1e-05 24.6 0.0 1.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 KOS16609.1 - 1.2e-05 25.6 0.0 3.9e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS16609.1 - 0.00014 21.4 0.0 0.00067 19.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS16609.1 - 0.0002 21.6 0.0 0.00052 20.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS16609.1 - 0.00049 20.1 0.1 0.0035 17.3 0.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KOS16609.1 - 0.0014 18.0 0.0 0.0029 16.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KOS16609.1 - 0.093 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF2235 PF09994.4 KOS16610.1 - 3.7e-75 252.8 2.7 6.3e-45 153.6 0.1 3.0 3 0 0 3 3 3 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) SelP_N PF04592.9 KOS16610.1 - 0.4 10.0 4.3 0.64 9.3 3.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Response_reg PF00072.19 KOS16611.1 - 5.6e-25 87.5 0.1 1.6e-24 86.0 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 KOS16611.1 - 4.2e-24 84.3 0.0 8.1e-24 83.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KOS16611.1 - 1.3e-16 60.3 0.1 3.9e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 KOS16611.1 - 1.8e-15 57.1 0.0 1.9e-12 47.4 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 KOS16611.1 - 4.7e-08 32.7 0.0 1.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 KOS16611.1 - 6.2e-08 32.6 0.0 7.3e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 PAS fold Cas_Cas4 PF01930.12 KOS16612.1 - 0.026 14.4 0.0 0.039 13.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF83 Radical_SAM PF04055.16 KOS16613.1 - 5.9e-13 49.3 0.5 1.3e-12 48.1 0.4 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 KOS16613.1 - 1.3e-07 31.6 0.4 3.1e-07 30.4 0.2 1.7 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 KOS16613.1 - 8e-07 29.2 1.8 1.1e-06 28.8 0.4 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain ShK PF01549.19 KOS16613.1 - 0.067 13.5 2.3 0.2 12.0 1.6 1.8 1 0 0 1 1 1 0 ShK domain-like DUF3246 PF11596.3 KOS16615.1 - 0.13 11.5 6.5 0.24 10.6 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Bd3614_N PF14442.1 KOS16615.1 - 1.7 8.6 18.3 0.11 12.4 1.6 2.9 3 0 0 3 3 3 0 Bd3614-like deaminase N-terminal AF1Q PF15017.1 KOS16615.1 - 1.8 8.5 9.0 1.7 8.6 2.6 2.4 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Nucleoplasmin PF03066.10 KOS16615.1 - 5.1 6.5 7.8 2.9 7.3 0.1 2.3 2 0 0 2 2 2 0 Nucleoplasmin SDA1 PF05285.7 KOS16615.1 - 5.5 6.1 6.9 3.8 6.6 3.7 1.4 2 0 0 2 2 2 0 SDA1 Prothymosin PF03247.9 KOS16615.1 - 6.4 6.9 14.0 11 6.2 0.7 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Mito_carr PF00153.22 KOS16616.1 - 8.2e-66 217.7 0.6 1.1e-20 73.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TspO_MBR PF03073.10 KOS16617.1 - 1.5e-41 141.3 8.9 1.8e-41 141.1 6.2 1.1 1 0 0 1 1 1 1 TspO/MBR family AAA_22 PF13401.1 KOS16618.1 - 2.7e-14 53.4 0.0 5.4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS16618.1 - 3.3e-13 50.0 0.0 1.2e-12 48.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KOS16618.1 - 1.7e-08 34.7 0.0 5.1e-08 33.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KOS16618.1 - 0.00012 21.8 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 KOS16618.1 - 0.00026 20.7 0.0 0.00056 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KOS16618.1 - 0.00034 20.2 0.0 0.00081 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.6 KOS16618.1 - 0.00037 20.1 0.0 0.0012 18.5 0.0 1.8 1 0 0 1 1 1 1 CDC6, C terminal AAA_14 PF13173.1 KOS16618.1 - 0.0019 18.1 0.0 0.0062 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KOS16618.1 - 0.0036 16.2 0.0 0.013 14.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 KOS16618.1 - 0.004 16.2 0.1 0.015 14.3 0.0 1.8 2 0 0 2 2 2 1 KAP family P-loop domain RNA_helicase PF00910.17 KOS16618.1 - 0.007 16.5 0.0 0.019 15.1 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_19 PF13245.1 KOS16618.1 - 0.0073 16.0 0.0 0.037 13.7 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain Rad17 PF03215.10 KOS16618.1 - 0.014 14.1 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 KOS16618.1 - 0.014 15.7 0.0 0.073 13.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.21 KOS16618.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.4 KOS16618.1 - 0.042 12.8 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_32 PF13654.1 KOS16618.1 - 0.055 12.1 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KOS16618.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.1 KOS16618.1 - 0.071 12.6 0.1 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KOS16618.1 - 0.11 12.0 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 KOS16618.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA_35 PF14516.1 KOS16618.1 - 0.17 10.5 0.0 0.42 9.1 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain SHR3_chaperone PF08229.6 KOS16619.1 - 1.8e-69 232.6 0.0 2.1e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 MFS_1 PF07690.11 KOS16619.1 - 0.71 8.5 7.7 1.1 7.8 5.3 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily MARVEL PF01284.18 KOS16619.1 - 3.8 7.3 9.2 20 4.9 0.1 2.7 2 1 0 2 2 2 0 Membrane-associating domain Mito_carr PF00153.22 KOS16620.1 - 7.2e-63 208.3 0.0 3.6e-21 74.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein IMS PF00817.15 KOS16621.1 - 8.7e-39 132.6 0.0 1.7e-38 131.7 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KOS16621.1 - 4e-18 65.5 0.0 9.3e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 KOS16621.1 - 2.1e-13 50.0 8.3 1e-06 28.5 2.4 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) BRCT PF00533.21 KOS16621.1 - 0.00027 21.0 0.0 0.00056 19.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 KOS16621.1 - 0.00034 20.4 0.2 0.0035 17.3 0.0 2.9 3 0 0 3 3 3 1 IMS family HHH motif MgtE_N PF03448.12 KOS16621.1 - 0.0049 17.1 1.4 0.98 9.7 0.1 3.3 3 0 0 3 3 3 1 MgtE intracellular N domain F420_ligase PF01996.11 KOS16621.1 - 0.035 13.1 0.1 0.067 12.2 0.1 1.4 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase WSC PF01822.14 KOS16622.1 - 4.5e-18 64.9 6.6 6.8e-18 64.3 4.6 1.3 1 0 0 1 1 1 1 WSC domain IU_nuc_hydro PF01156.14 KOS16623.1 - 4.6e-59 200.1 0.0 5.6e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.8 KOS16624.1 - 5.3e-08 32.3 2.6 5.3e-08 32.3 1.8 2.6 3 0 0 3 3 3 1 RED-like protein N-terminal region FA_hydroxylase PF04116.8 KOS16625.1 - 1e-19 70.9 10.1 1e-19 70.9 7.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Mg_trans_NIPA PF05653.9 KOS16626.1 - 6.2e-62 209.2 6.8 2.6e-59 200.6 2.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KOS16626.1 - 5.9e-05 23.2 0.7 5.9e-05 23.2 0.5 3.5 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KOS16626.1 - 0.0079 16.2 0.9 0.0079 16.2 0.6 4.0 2 1 2 4 4 4 2 EamA-like transporter family YfhO PF09586.5 KOS16626.1 - 0.039 11.9 2.7 0.057 11.4 1.9 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO ADH_zinc_N PF00107.21 KOS16627.1 - 3.4e-22 78.3 0.0 5.1e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KOS16627.1 - 2.5e-06 28.4 0.0 5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PPR_2 PF13041.1 KOS16628.1 - 1.4e-17 63.4 0.0 1e-07 31.7 0.0 6.5 5 2 2 7 7 7 5 PPR repeat family PPR_3 PF13812.1 KOS16628.1 - 1.5e-12 46.7 2.7 0.00053 20.0 0.0 8.2 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR PF01535.15 KOS16628.1 - 1e-06 28.2 0.0 1.1 9.4 0.1 4.8 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.2 KOS16628.1 - 2.5e-06 26.8 0.1 0.068 12.6 0.0 5.0 6 0 0 6 6 6 2 PPR repeat Glyoxalase_2 PF12681.2 KOS16628.1 - 0.077 13.6 0.1 28 5.3 0.0 3.4 3 1 1 4 4 4 0 Glyoxalase-like domain TPR_14 PF13428.1 KOS16628.1 - 0.36 11.5 12.8 34 5.4 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Mis12 PF05859.7 KOS16629.1 - 2e-32 111.9 0.0 3.5e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein CTP_transf_3 PF02348.14 KOS16629.1 - 0.059 12.9 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase EMP24_GP25L PF01105.19 KOS16630.1 - 2.7e-44 151.0 0.3 3.1e-44 150.8 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3405 PF11885.3 KOS16631.1 - 1.4e-206 686.5 0.0 1.7e-206 686.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) RRM_1 PF00076.17 KOS16633.1 - 2.6e-14 52.6 0.0 2.2e-06 27.2 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16633.1 - 3e-13 49.5 0.0 1.5e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16633.1 - 8e-07 28.8 0.0 4e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Serglycin PF04360.7 KOS16633.1 - 0.0099 15.6 0.5 0.017 14.8 0.3 1.4 1 0 0 1 1 1 1 Serglycin U1snRNP70_N PF12220.3 KOS16633.1 - 0.089 13.1 1.2 0.21 11.9 0.9 1.6 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2201_N PF13203.1 KOS16633.1 - 2.5 7.2 9.0 0.31 10.1 1.7 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain Peptidase_M49 PF03571.10 KOS16634.1 - 5.2e-228 757.6 0.0 6.1e-228 757.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.5 KOS16634.1 - 0.1 12.5 0.4 0.22 11.4 0.3 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain Ribosomal_L6e PF01159.14 KOS16635.1 - 2.2e-36 124.3 0.5 2.2e-36 124.3 0.4 1.4 2 0 0 2 2 2 1 Ribosomal protein L6e AAA_2 PF07724.9 KOS16636.1 - 8.5e-46 155.9 0.0 2.8e-44 151.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KOS16636.1 - 8.5e-24 83.2 0.1 3.5e-23 81.3 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KOS16636.1 - 5.3e-20 71.9 2.5 5.2e-11 42.8 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS16636.1 - 1.3e-13 50.9 0.1 4e-09 36.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KOS16636.1 - 1.1e-11 45.0 10.7 5.8e-05 23.1 0.0 5.2 4 2 1 6 6 5 3 AAA ATPase domain AAA_22 PF13401.1 KOS16636.1 - 1.9e-10 41.0 0.3 0.00083 19.5 0.0 3.2 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 KOS16636.1 - 5.6e-08 32.4 0.2 0.00012 21.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 KOS16636.1 - 2.4e-07 31.5 3.1 0.0038 18.0 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.1 KOS16636.1 - 8.8e-07 28.8 0.0 0.048 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KOS16636.1 - 1.4e-06 28.6 4.0 0.051 13.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 KOS16636.1 - 1.7e-06 27.9 7.0 0.012 15.3 0.4 4.4 3 2 0 3 3 2 2 Archaeal ATPase NACHT PF05729.7 KOS16636.1 - 7.6e-06 25.6 0.0 0.17 11.5 0.0 2.7 2 1 0 2 2 2 2 NACHT domain MobB PF03205.9 KOS16636.1 - 1.9e-05 24.3 0.0 0.019 14.6 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KOS16636.1 - 7.1e-05 22.4 0.0 0.014 15.1 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 KOS16636.1 - 0.00016 21.1 0.0 0.24 10.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 KOS16636.1 - 0.00042 20.3 0.2 0.87 9.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 KOS16636.1 - 0.00056 20.0 0.0 0.28 11.3 0.0 2.9 2 1 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 KOS16636.1 - 0.00099 19.4 0.8 0.78 10.0 0.0 3.3 3 0 0 3 3 3 1 ABC transporter SRP54 PF00448.17 KOS16636.1 - 0.0011 18.4 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.4 KOS16636.1 - 0.0023 16.5 0.1 0.35 9.4 0.0 2.7 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain OEP PF02321.13 KOS16636.1 - 0.003 17.1 2.8 0.0062 16.1 1.9 1.5 1 0 0 1 1 1 1 Outer membrane efflux protein MMR_HSR1 PF01926.18 KOS16636.1 - 0.0042 17.0 0.1 0.64 9.9 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KOS16636.1 - 0.0047 16.4 0.1 0.31 10.4 0.0 3.2 2 2 0 2 2 2 1 AAA-like domain Mg_chelatase PF01078.16 KOS16636.1 - 0.0064 15.6 0.1 1.7 7.7 0.0 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KOS16636.1 - 0.007 15.9 0.0 0.39 10.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 KOS16636.1 - 0.0079 15.4 0.0 2.9 7.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF815 PF05673.8 KOS16636.1 - 0.0085 15.0 0.6 0.33 9.8 0.1 3.2 3 1 0 3 3 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.1 KOS16636.1 - 0.015 15.6 4.9 12 6.0 2.5 3.3 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 KOS16636.1 - 0.017 14.5 0.2 2.3 7.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 KOS16636.1 - 0.022 15.2 0.0 1.2 9.6 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein ResIII PF04851.10 KOS16636.1 - 0.024 14.4 2.4 1.7 8.4 0.0 3.2 3 1 0 4 4 3 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 KOS16636.1 - 0.024 14.2 0.0 0.86 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KOS16636.1 - 0.025 14.0 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 KOS16636.1 - 0.031 14.1 0.0 3.2 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 KOS16636.1 - 0.032 13.1 0.0 1.6 7.6 0.0 2.5 3 0 0 3 3 2 0 PIF1-like helicase UPF0079 PF02367.12 KOS16636.1 - 0.043 13.4 0.0 14 5.3 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 KOS16636.1 - 0.044 13.0 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ATP_bind_1 PF03029.12 KOS16636.1 - 0.045 13.2 0.0 0.49 9.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 KOS16636.1 - 0.045 13.4 0.2 0.91 9.2 0.0 2.8 3 0 0 3 3 2 0 NTPase APG6 PF04111.7 KOS16636.1 - 0.069 12.1 4.5 0.12 11.4 3.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_15 PF13175.1 KOS16636.1 - 0.083 11.9 2.4 0.17 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain CENP-F_leu_zip PF10473.4 KOS16636.1 - 0.084 12.7 11.3 0.3 10.9 7.8 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_29 PF13555.1 KOS16636.1 - 0.091 12.3 0.0 4.1 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Atg14 PF10186.4 KOS16636.1 - 0.14 11.0 7.6 0.26 10.2 5.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KOS16636.1 - 0.19 11.3 11.6 0.011 15.3 3.8 2.0 3 0 0 3 3 2 0 IncA protein Mnd1 PF03962.10 KOS16636.1 - 1.1 8.9 10.2 2.2 7.9 7.1 1.4 1 0 0 1 1 1 0 Mnd1 family DUF87 PF01935.12 KOS16636.1 - 1.5 8.5 5.9 12 5.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 Seryl_tRNA_N PF02403.17 KOS16636.1 - 3.9 7.5 13.4 15 5.6 7.9 3.1 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.1 KOS16636.1 - 5.3 7.5 8.7 1e+02 3.4 5.1 3.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Arf PF00025.16 KOS16637.1 - 2.9e-79 264.3 0.2 3.4e-79 264.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KOS16637.1 - 1.4e-14 53.6 0.0 1.8e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KOS16637.1 - 2.1e-13 49.9 0.0 2.4e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KOS16637.1 - 2.5e-12 46.2 1.6 2.8e-09 36.1 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KOS16637.1 - 5.1e-11 42.1 0.0 5.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KOS16637.1 - 7.4e-09 36.1 0.0 1.1e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KOS16637.1 - 5e-06 26.4 0.0 6.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KOS16637.1 - 0.0086 15.1 0.5 0.018 14.0 0.3 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KOS16637.1 - 0.018 14.5 0.1 0.14 11.5 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KOS16637.1 - 0.04 13.8 0.2 0.1 12.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain 2-oxoacid_dh PF00198.18 KOS16638.1 - 2.7e-74 249.3 0.0 3.5e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KOS16638.1 - 2.4e-16 59.1 0.1 4.7e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KOS16638.1 - 4.3e-11 42.2 0.1 1.2e-10 40.7 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain BEX PF04538.7 KOS16638.1 - 0.025 14.7 0.1 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 Brain expressed X-linked like family SKI PF01202.17 KOS16639.1 - 3.1e-13 49.9 0.0 4.3e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 KOS16639.1 - 6.1e-13 48.8 0.0 2e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KOS16639.1 - 1.2e-11 45.4 0.0 1.6e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KOS16639.1 - 6.6e-10 39.3 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KOS16639.1 - 5e-06 26.7 0.1 1.4e-05 25.2 0.0 2.0 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KOS16639.1 - 2.3e-05 23.3 0.0 3.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KOS16639.1 - 2.4e-05 23.9 0.1 6.6e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KOS16639.1 - 3.4e-05 23.9 0.0 6.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS16639.1 - 4.6e-05 23.4 0.0 7.3e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 KOS16639.1 - 7.1e-05 22.8 0.1 0.00011 22.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 KOS16639.1 - 0.00036 20.2 0.0 0.00054 19.6 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase RuvB_N PF05496.7 KOS16639.1 - 0.00041 19.4 0.1 0.00083 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KOS16639.1 - 0.00051 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.1 KOS16639.1 - 0.00061 19.7 0.0 0.0064 16.4 0.0 2.3 1 1 1 2 2 2 1 Cytidylate kinase-like family AAA_14 PF13173.1 KOS16639.1 - 0.00078 19.3 0.0 0.0035 17.2 0.0 1.9 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KOS16639.1 - 0.0013 17.9 2.5 0.0019 17.3 0.3 2.1 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KOS16639.1 - 0.0017 18.0 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PRK PF00485.13 KOS16639.1 - 0.0029 17.2 0.0 0.0064 16.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family T2SE PF00437.15 KOS16639.1 - 0.0038 16.1 0.3 0.0069 15.3 0.2 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.17 KOS16639.1 - 0.0045 17.1 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase PhoH PF02562.11 KOS16639.1 - 0.0048 16.1 0.1 0.0093 15.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein NTPase_1 PF03266.10 KOS16639.1 - 0.01 15.5 0.0 0.027 14.1 0.0 1.8 1 1 1 2 2 2 0 NTPase Zeta_toxin PF06414.7 KOS16639.1 - 0.012 14.6 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin CoaE PF01121.15 KOS16639.1 - 0.017 14.4 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_30 PF13604.1 KOS16639.1 - 0.017 14.6 0.4 0.04 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 KOS16639.1 - 0.018 14.4 0.0 4.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase cobW PF02492.14 KOS16639.1 - 0.019 14.3 0.0 0.036 13.5 0.0 1.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 KOS16639.1 - 0.024 14.0 0.2 0.045 13.1 0.1 1.5 2 0 0 2 2 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 KOS16639.1 - 0.025 14.2 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase CobU PF02283.11 KOS16639.1 - 0.025 13.9 0.0 0.052 12.9 0.0 1.6 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase ABC_tran PF00005.22 KOS16639.1 - 0.028 14.7 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ADK PF00406.17 KOS16639.1 - 0.029 14.2 0.2 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase Sigma54_activ_2 PF14532.1 KOS16639.1 - 0.035 14.1 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.9 KOS16639.1 - 0.036 13.7 0.0 0.094 12.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KOS16639.1 - 0.037 13.2 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2075 PF09848.4 KOS16639.1 - 0.04 12.8 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KOS16639.1 - 0.05 12.9 0.1 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KOS16639.1 - 0.056 12.9 0.0 0.16 11.4 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain KaiC PF06745.8 KOS16639.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 KaiC Thermopsin PF05317.6 KOS16639.1 - 0.088 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Thermopsin Herpes_Helicase PF02689.9 KOS16639.1 - 0.09 10.5 0.1 0.12 10.1 0.1 1.1 1 0 0 1 1 1 0 Helicase AAA_PrkA PF08298.6 KOS16639.1 - 0.096 11.3 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain NB-ARC PF00931.17 KOS16639.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Herpes_capsid PF06112.6 KOS16639.1 - 4.2 7.3 7.4 7.2 6.6 5.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Sigma70_ner PF04546.8 KOS16640.1 - 0.04 13.5 2.1 0.054 13.0 1.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 KOS16640.1 - 8.6 4.2 8.9 11 3.8 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 KOS16641.1 - 3.7e-65 213.6 12.7 7.1e-10 38.3 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KOS16641.1 - 4.7e-24 84.3 9.9 7.1e-24 83.7 6.9 1.2 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 KOS16641.1 - 0.013 13.6 0.3 0.65 8.0 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 LXG PF04740.7 KOS16641.1 - 0.031 14.0 1.3 0.046 13.4 0.9 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Myosin_tail_1 PF01576.14 KOS16641.1 - 0.1 10.3 3.6 0.14 9.8 2.5 1.0 1 0 0 1 1 1 0 Myosin tail Nucleoporin_N PF08801.6 KOS16641.1 - 0.17 10.5 0.0 4.2 5.9 0.0 2.4 1 1 1 2 2 2 0 Nup133 N terminal like DUF724 PF05266.9 KOS16641.1 - 0.25 10.9 2.5 0.38 10.3 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) IncA PF04156.9 KOS16641.1 - 4.7 6.7 5.1 7.2 6.1 3.5 1.1 1 0 0 1 1 1 0 IncA protein PAT1 PF09770.4 KOS16641.1 - 5.8 5.0 43.2 7.9 4.5 29.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-rbx1 PF12678.2 KOS16642.1 - 5e-35 119.4 13.2 6.2e-35 119.1 9.1 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KOS16642.1 - 4.7e-17 61.6 9.8 6e-17 61.2 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KOS16642.1 - 6.6e-07 29.0 11.7 4.5e-06 26.3 8.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KOS16642.1 - 0.0015 18.1 11.5 0.028 14.0 8.0 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS16642.1 - 0.0035 16.9 9.3 0.43 10.2 6.6 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS16642.1 - 0.052 13.5 12.7 0.055 13.5 5.4 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KOS16642.1 - 0.67 9.9 9.1 4 7.4 6.4 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.1 KOS16642.1 - 0.68 9.7 11.5 7.2 6.4 8.0 2.5 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 KOS16642.1 - 0.75 9.9 10.5 55 3.9 7.3 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KOS16642.1 - 0.86 9.6 10.2 2.8 7.9 7.1 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 KOS16642.1 - 1.2 8.9 6.7 29 4.4 4.7 2.2 1 1 0 1 1 1 0 RING-type zinc-finger CorA PF01544.13 KOS16643.1 - 7.2e-39 133.5 0.0 1e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-Tim10_DDP PF02953.10 KOS16644.1 - 5.5e-22 76.8 3.5 7.6e-22 76.3 2.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L23 PF00276.15 KOS16645.1 - 3.9e-17 61.9 1.4 7.7e-17 61.0 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 KOS16645.1 - 4.5e-16 58.6 10.0 4.5e-16 58.6 6.9 2.6 2 2 0 2 2 2 1 Ribosomal protein L23, N-terminal domain DUF3321 PF11968.3 KOS16646.1 - 6e-83 277.8 0.0 8.1e-83 277.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KOS16646.1 - 0.0056 16.4 0.0 0.024 14.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain HAD_2 PF13419.1 KOS16647.1 - 4.5e-22 79.0 0.1 5.7e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Pkinase PF00069.20 KOS16648.1 - 2.5e-60 203.8 0.0 4e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS16648.1 - 9.3e-37 126.4 0.0 1.4e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS16648.1 - 1.3e-12 47.3 0.0 2.4e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KOS16648.1 - 0.0038 16.3 0.0 0.01 14.8 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Aa_trans PF01490.13 KOS16649.1 - 7e-53 179.5 19.9 9.6e-53 179.1 13.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KOS16649.1 - 9.7e-05 21.3 8.1 9.7e-05 21.3 5.6 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family LRR_6 PF13516.1 KOS16650.1 - 1.7e-10 39.8 0.5 0.027 14.5 0.0 6.3 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 KOS16650.1 - 2.3e-07 30.2 2.2 0.0042 16.6 0.0 4.9 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KOS16650.1 - 2.8e-05 23.5 1.2 6 7.3 0.0 5.5 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 KOS16650.1 - 0.01 15.8 1.4 86 4.0 0.0 5.1 5 0 0 5 5 5 0 Leucine rich repeat LRR_8 PF13855.1 KOS16650.1 - 0.025 14.3 5.1 3.4 7.4 0.0 4.6 3 2 0 3 3 3 0 Leucine rich repeat LETM1 PF07766.8 KOS16650.1 - 0.3 10.1 0.0 0.3 10.1 0.0 1.9 2 0 0 2 2 2 0 LETM1-like protein IncA PF04156.9 KOS16650.1 - 4.1 6.9 14.9 6.7 6.2 10.3 1.3 1 0 0 1 1 1 0 IncA protein SURF2 PF05477.6 KOS16650.1 - 8 5.5 12.4 11 5.0 8.6 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Cytochrom_C1 PF02167.10 KOS16651.1 - 8.6e-80 267.4 0.0 1.1e-79 267.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KOS16651.1 - 0.0054 16.8 0.0 0.012 15.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Herpes_pp38 PF04846.8 KOS16652.1 - 0.032 13.5 0.1 0.061 12.6 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein PCI PF01399.22 KOS16653.1 - 4.1e-12 46.3 0.0 8.8e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_12 PF13424.1 KOS16653.1 - 2.4e-06 27.3 2.5 0.0041 17.0 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KOS16653.1 - 0.00071 19.1 0.1 0.1 12.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KOS16653.1 - 0.00098 18.8 0.3 1.2 9.1 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KOS16653.1 - 0.007 16.9 0.4 20 6.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KOS16653.1 - 0.024 14.2 0.6 0.4 10.3 0.1 2.4 1 1 2 3 3 3 0 TPR repeat RPN7 PF10602.4 KOS16653.1 - 0.033 13.5 0.2 0.033 13.5 0.1 1.8 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_1 PF00515.23 KOS16653.1 - 0.039 13.5 0.1 0.36 10.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Ras PF00071.17 KOS16654.1 - 1.9e-53 180.1 0.0 2.3e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS16654.1 - 4.3e-16 59.4 0.0 5.6e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS16654.1 - 2.6e-08 33.3 0.0 5.7e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KOS16654.1 - 0.001 18.2 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KOS16654.1 - 0.0052 16.0 0.0 0.0068 15.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KOS16654.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 KOS16654.1 - 0.018 13.7 0.0 0.034 12.8 0.0 1.2 1 1 0 1 1 1 0 G-protein alpha subunit PduV-EutP PF10662.4 KOS16654.1 - 0.034 13.6 0.0 1.3 8.5 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 KOS16654.1 - 0.098 12.9 0.0 0.26 11.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 KOS16654.1 - 0.15 11.7 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Ribosomal_L37 PF08561.5 KOS16656.1 - 2.2e-30 104.0 4.7 4.8e-23 80.5 0.3 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L37 NDUFB10 PF10249.4 KOS16657.1 - 0.0047 17.0 0.0 0.0056 16.8 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 RRM_1 PF00076.17 KOS16658.1 - 1.2e-40 136.9 0.1 1.3e-21 75.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16658.1 - 2.1e-27 94.8 0.0 2.7e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16658.1 - 2.4e-09 36.9 0.0 0.00073 19.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ERM PF00769.14 KOS16659.1 - 0.0092 15.5 7.1 0.0092 15.5 5.0 5.7 4 1 0 4 4 4 1 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.3 KOS16659.1 - 0.016 15.0 2.7 0.016 15.0 1.9 9.7 8 3 0 8 8 8 0 TATA element modulatory factor 1 DNA binding KSR1-SAM PF13543.1 KOS16659.1 - 0.25 11.1 9.6 1.8 8.3 0.2 3.7 3 1 0 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 APS_kinase PF01583.15 KOS16659.1 - 0.35 10.5 3.5 5.8 6.5 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Reo_sigmaC PF04582.7 KOS16659.1 - 0.84 8.7 19.3 0.54 9.3 0.4 4.5 4 1 0 4 4 4 0 Reovirus sigma C capsid protein Filament PF00038.16 KOS16659.1 - 1.1 8.5 76.0 0.33 10.3 21.7 5.8 3 2 0 3 3 3 0 Intermediate filament protein Med16 PF11635.3 KOS16661.1 - 7e-97 325.2 0.0 4e-52 177.2 0.0 2.0 1 1 1 2 2 2 2 Mediator complex subunit 16 Glyco_hydro_16 PF00722.16 KOS16662.1 - 0.019 14.2 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 GTP_EFTU PF00009.22 KOS16663.1 - 5.3e-54 182.5 0.0 9.9e-54 181.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KOS16663.1 - 1.5e-16 60.0 0.0 5.5e-16 58.1 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KOS16663.1 - 1.7e-10 40.8 0.0 5.5e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KOS16663.1 - 1.1e-07 31.6 0.0 4.7e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_IV PF03764.13 KOS16663.1 - 1.2e-05 24.8 0.0 0.001 18.6 0.0 2.7 2 1 0 2 2 2 1 Elongation factor G, domain IV SET PF00856.23 KOS16663.1 - 0.015 15.5 0.0 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 SET domain Fungal_trans PF04082.13 KOS16664.1 - 3.3e-25 88.4 0.9 3.3e-25 88.4 0.7 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS16664.1 - 0.00043 20.1 5.8 0.00074 19.3 4.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim54 PF11711.3 KOS16664.1 - 0.008 14.8 2.5 0.013 14.1 1.7 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF3619 PF12279.3 KOS16664.1 - 0.028 14.4 3.1 0.095 12.7 2.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Suf PF05843.9 KOS16664.1 - 0.074 12.7 7.8 0.13 11.9 5.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 KOS16664.1 - 2.4 8.2 14.8 6.4 6.8 10.2 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4557 PF15101.1 KOS16664.1 - 3.4 7.4 15.9 2.3 8.0 9.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) UPF0560 PF10577.4 KOS16664.1 - 6.3 4.9 16.1 9.9 4.2 11.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4175 PF13779.1 KOS16664.1 - 7 4.2 33.2 11 3.6 23.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ndc1_Nup PF09531.5 KOS16664.1 - 7.7 4.7 10.2 3.1 6.1 5.2 1.6 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Fungal_trans PF04082.13 KOS16665.1 - 1.2e-14 53.8 0.0 1.9e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS16665.1 - 1.2e-06 28.2 10.6 2.3e-06 27.4 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIB PF00382.14 KOS16666.1 - 2e-34 117.2 0.7 2.1e-20 72.3 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KOS16666.1 - 7.4e-11 41.1 3.2 1.3e-10 40.4 2.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 KOS16666.1 - 0.00042 20.2 0.1 0.24 11.3 0.0 2.8 2 1 1 3 3 3 2 Cyclin, C-terminal domain Cyclin_N PF00134.18 KOS16666.1 - 0.0045 16.5 0.7 0.024 14.1 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Sigma70_r4_2 PF08281.7 KOS16666.1 - 0.034 13.6 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 RB_B PF01857.15 KOS16666.1 - 0.048 13.1 0.1 0.075 12.5 0.1 1.4 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain HTH_Tnp_ISL3 PF13542.1 KOS16666.1 - 0.09 11.9 0.0 1.3 8.2 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 FA_hydroxylase PF04116.8 KOS16667.1 - 1.7e-13 50.9 17.7 1.7e-13 50.9 12.3 2.4 2 1 0 2 2 2 2 Fatty acid hydroxylase superfamily E1-E2_ATPase PF00122.15 KOS16668.1 - 2.4e-17 62.7 0.0 4.9e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KOS16668.1 - 4.2e-17 63.2 0.0 1.4e-16 61.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KOS16668.1 - 6.1e-12 46.1 0.0 1.9e-10 41.2 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS16668.1 - 1.6e-09 37.6 0.0 5.1e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KOS16668.1 - 0.023 14.2 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2015 PF09435.5 KOS16669.1 - 2.7e-42 143.5 0.0 3e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DNA_ligase_OB_2 PF14743.1 KOS16669.1 - 0.082 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 DNA ligase OB-like domain CoA_transf_3 PF02515.12 KOS16670.1 - 1.2e-56 191.0 0.0 1.9e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III ExbD PF02472.11 KOS16670.1 - 0.014 15.4 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Ribosomal_L28e PF01778.12 KOS16671.1 - 9.3e-37 126.0 0.3 1.2e-36 125.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Glycos_transf_3 PF00591.16 KOS16672.1 - 1.7e-60 204.5 0.0 2.8e-60 203.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KOS16672.1 - 1.4e-10 40.5 0.0 4.7e-10 38.9 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain HHH_5 PF14520.1 KOS16672.1 - 0.044 13.9 0.2 0.36 11.0 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain HTH_psq PF05225.11 KOS16672.1 - 0.21 11.1 0.7 0.48 10.0 0.2 1.9 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Ldh_1_C PF02866.13 KOS16673.1 - 4e-44 150.3 0.0 6.1e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KOS16673.1 - 2.8e-43 147.1 0.1 3.8e-43 146.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KOS16673.1 - 0.0008 18.1 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KOS16673.1 - 0.056 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Asn_synthase PF00733.16 KOS16674.1 - 2.7e-54 184.3 0.0 3.6e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KOS16674.1 - 4.8e-09 36.0 0.0 2.2e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KOS16674.1 - 1.1e-06 28.5 0.0 2.8e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF2423 PF10338.4 KOS16676.1 - 8.5e-16 57.6 5.6 8.5e-16 57.6 3.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) DUF2589 PF11655.3 KOS16676.1 - 0.06 13.4 1.0 0.093 12.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2589) PDCD2_C PF04194.8 KOS16676.1 - 0.25 10.9 1.2 0.3 10.6 0.8 1.2 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Pox_RNA_Pol_19 PF05320.7 KOS16676.1 - 0.46 10.2 4.7 0.4 10.4 2.5 1.4 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit AICARFT_IMPCHas PF01808.13 KOS16677.1 - 6e-112 373.7 0.0 7.8e-112 373.4 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KOS16677.1 - 3.6e-23 81.3 0.0 6.6e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain zf-C2H2 PF00096.21 KOS16678.1 - 0.021 15.1 2.6 0.021 15.1 1.8 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS16678.1 - 0.42 11.0 17.5 0.4 11.1 1.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger FMN_dh PF01070.13 KOS16679.1 - 3.6e-115 384.6 0.0 4.2e-115 384.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 KOS16679.1 - 8.4e-05 21.8 2.2 0.00011 21.5 1.0 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 KOS16679.1 - 0.00053 19.1 0.8 0.13 11.2 0.1 2.6 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 KOS16679.1 - 0.0015 17.5 0.2 0.0031 16.4 0.2 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase PcrB PF01884.12 KOS16679.1 - 0.0054 16.0 0.0 1.2 8.3 0.0 2.5 2 0 0 2 2 2 2 PcrB family IMPDH PF00478.20 KOS16679.1 - 0.012 14.5 2.4 0.44 9.3 0.3 2.6 2 1 1 3 3 3 0 IMP dehydrogenase / GMP reductase domain Far-17a_AIG1 PF04750.9 KOS16680.1 - 3.1e-53 179.9 12.7 3.5e-53 179.7 8.8 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Claudin_2 PF13903.1 KOS16680.1 - 0.93 9.1 14.9 0.14 11.8 2.8 2.2 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction WD40 PF00400.27 KOS16681.1 - 1.2e-08 34.5 0.0 0.27 11.2 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Sld5 PF05916.6 KOS16682.1 - 3.2e-08 33.8 0.3 5e-08 33.1 0.2 1.3 1 0 0 1 1 1 1 GINS complex protein FAD_binding_3 PF01494.14 KOS16683.1 - 2.7e-63 214.1 0.0 3.3e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KOS16683.1 - 7.7e-34 116.7 0.0 1.2e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 KOS16683.1 - 1.5e-05 24.9 0.0 7.6e-05 22.6 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS16683.1 - 1.8e-05 25.0 0.0 0.0053 17.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KOS16683.1 - 6.6e-05 21.5 0.0 0.0001 20.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 KOS16683.1 - 0.00035 20.5 0.0 0.00082 19.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KOS16683.1 - 0.00061 18.8 0.2 0.00098 18.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KOS16683.1 - 0.00093 19.3 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KOS16683.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 KOS16683.1 - 0.012 14.5 0.1 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KOS16683.1 - 0.044 12.4 0.0 0.093 11.3 0.0 1.5 1 1 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KOS16683.1 - 0.049 13.3 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding XdhC_C PF13478.1 KOS16683.1 - 0.086 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain GIDA PF01134.17 KOS16683.1 - 0.091 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KOS16683.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KOS16683.1 - 0.15 10.8 0.1 0.25 10.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Indigoidine_A PF04227.7 KOS16684.1 - 1.5e-101 339.5 0.7 2.2e-101 338.9 0.5 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 KOS16684.1 - 2.1e-20 73.0 0.3 1.6e-18 66.8 0.2 2.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Calreticulin PF00262.13 KOS16685.1 - 1.2e-159 530.9 16.9 1.4e-159 530.6 11.7 1.1 1 0 0 1 1 1 1 Calreticulin family AGTRAP PF06396.6 KOS16685.1 - 0.23 11.1 0.1 0.41 10.3 0.1 1.3 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Aldedh PF00171.17 KOS16686.1 - 3.5e-130 434.4 0.1 4e-130 434.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KOS16686.1 - 0.0074 15.0 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) GTP_cyclohydro2 PF00925.15 KOS16686.1 - 0.092 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase II Aldolase_II PF00596.16 KOS16687.1 - 4.8e-40 137.1 0.0 6.3e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF2201_N PF13203.1 KOS16688.1 - 0.054 12.6 2.8 0.066 12.3 1.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain MAGP PF05507.6 KOS16688.1 - 0.071 12.9 1.5 0.095 12.5 1.0 1.2 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) RAP1 PF07218.6 KOS16688.1 - 4.4 5.2 15.5 5.1 5.0 10.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CRT10 PF08728.5 KOS16689.1 - 9.5e-12 43.7 0.0 1.2e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 CRT10 CRT10 PF08728.5 KOS16690.1 - 0.027 12.5 0.0 0.085 10.8 0.0 1.7 2 1 0 2 2 2 0 CRT10 Ammonium_transp PF00909.16 KOS16691.1 - 1.1e-112 376.3 28.0 1.3e-112 376.1 19.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family His_Phos_2 PF00328.17 KOS16692.1 - 7.3e-39 134.0 0.0 8.7e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Methyltrans_Mon PF14314.1 KOS16693.1 - 0.039 11.8 0.7 1.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Virus-capping methyltransferase DUF3627 PF12299.3 KOS16693.1 - 0.1 12.6 0.2 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3627) Pkinase PF00069.20 KOS16694.1 - 3.7e-06 26.2 0.0 1e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS16694.1 - 0.0033 16.5 0.0 0.015 14.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase RRM_1 PF00076.17 KOS16695.1 - 6.8e-19 67.2 0.2 1.2e-18 66.4 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16695.1 - 9.5e-14 51.1 0.0 1.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16695.1 - 3.6e-09 36.3 0.2 5.6e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KOS16696.1 - 2.3e-47 161.3 0.0 4.1e-47 160.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS16696.1 - 2.2e-14 53.1 0.0 2.8e-13 49.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase FAM220 PF15487.1 KOS16696.1 - 0.016 14.6 7.6 0.028 13.7 5.3 1.5 1 1 0 1 1 1 0 FAM220 family PAP1 PF08601.5 KOS16696.1 - 7.3 6.1 8.6 11 5.5 5.9 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 HhH-GPD PF00730.20 KOS16697.1 - 0.0028 17.9 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SURF4 PF02077.10 KOS16698.1 - 4e-98 328.0 6.3 4.5e-98 327.8 4.3 1.0 1 0 0 1 1 1 1 SURF4 family HR_lesion PF05514.6 KOS16698.1 - 8.3 6.2 11.9 0.33 10.7 0.7 3.2 4 0 0 4 4 4 0 HR-like lesion-inducing TCTP PF00838.12 KOS16700.1 - 6.4e-63 211.6 1.8 7.1e-63 211.4 1.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein FAM74 PF15026.1 KOS16701.1 - 0.067 12.8 1.1 0.13 11.9 0.7 1.5 1 0 0 1 1 1 0 FAM74 protein Sel1 PF08238.7 KOS16702.1 - 4.3e-14 52.6 0.6 3.6e-06 27.4 0.1 2.8 2 0 0 2 2 2 2 Sel1 repeat TraC PF07820.7 KOS16702.1 - 0.028 14.6 0.9 0.18 12.0 0.0 2.5 2 0 0 2 2 2 0 TraC-like protein bZIP_1 PF00170.16 KOS16703.1 - 2e-08 34.0 17.4 4.1e-08 33.0 8.5 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 KOS16703.1 - 7.2e-06 26.2 12.4 7.5e-06 26.1 7.4 1.9 1 1 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 KOS16703.1 - 0.00036 20.2 12.3 0.00036 20.2 8.5 2.7 2 1 0 2 2 2 1 Basic region leucine zipper Endotoxin_N PF03945.9 KOS16703.1 - 0.34 10.2 7.4 0.19 11.0 2.2 2.2 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain DUF342 PF03961.8 KOS16703.1 - 0.45 8.8 10.4 0.66 8.3 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PEP-utilisers_N PF05524.8 KOS16703.1 - 0.68 9.7 7.2 0.21 11.3 1.2 2.7 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal TMF_TATA_bd PF12325.3 KOS16703.1 - 1.3 8.8 16.4 0.023 14.4 2.8 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.14 KOS16703.1 - 5.7 4.6 6.4 9.7 3.8 4.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sua5_yciO_yrdC PF01300.13 KOS16704.1 - 7.6e-53 178.4 0.0 1.6e-52 177.3 0.0 1.5 1 1 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KOS16704.1 - 1.9e-23 82.8 0.0 6.1e-23 81.2 0.0 1.8 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding COG4 PF08318.7 KOS16705.1 - 5.5e-87 291.6 0.0 6.7e-86 288.0 0.0 2.1 1 1 0 1 1 1 1 COG4 transport protein E1-E2_ATPase PF00122.15 KOS16705.1 - 7.6e-72 241.0 0.0 1.4e-71 240.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KOS16705.1 - 1.7e-44 151.4 0.1 3.1e-44 150.6 0.1 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KOS16705.1 - 5.2e-29 102.1 0.0 2.2e-28 100.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KOS16705.1 - 5.5e-20 70.6 0.1 1.4e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KOS16705.1 - 2.3e-14 53.1 0.0 6.2e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KOS16705.1 - 9.6e-14 51.9 0.0 2.4e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KOS16705.1 - 6.9e-05 22.5 1.5 0.00023 20.8 0.5 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MCM PF00493.18 KOS16706.1 - 1.3e-139 464.6 0.1 1.8e-139 464.1 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KOS16706.1 - 3.4e-25 88.8 0.0 1.2e-24 87.1 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KOS16706.1 - 9.6e-06 24.9 0.0 0.00044 19.4 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KOS16706.1 - 1.1e-05 25.1 0.1 7.4e-05 22.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KOS16706.1 - 0.0024 17.4 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 KOS16706.1 - 0.0094 14.6 0.7 0.016 13.9 0.5 1.3 1 0 0 1 1 1 1 AAA domain Clat_adaptor_s PF01217.15 KOS16707.1 - 1.9e-15 56.8 1.0 1.6e-14 53.8 0.7 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain THOC7 PF05615.8 KOS16708.1 - 6.6e-32 110.6 0.0 4.1e-31 108.1 0.0 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 Sporozoite_P67 PF05642.6 KOS16708.1 - 0.00074 17.5 0.0 0.0029 15.5 0.0 1.8 1 1 1 2 2 2 1 Sporozoite P67 surface antigen zf-C4H2 PF10146.4 KOS16708.1 - 5.1 7.0 14.7 49 3.8 9.6 2.8 1 1 1 2 2 2 0 Zinc finger-containing protein zf-CCCH PF00642.19 KOS16709.1 - 1.6e-05 24.4 26.1 0.029 14.0 0.7 5.3 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Rad21_Rec8_N PF04825.8 KOS16710.1 - 5e-39 132.6 0.0 8.4e-39 131.9 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KOS16710.1 - 2.9e-08 32.7 0.1 6e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KOS16710.1 - 0.013 15.1 0.2 0.057 12.9 0.0 2.0 3 0 0 3 3 3 0 ScpA/B protein TBCA PF02970.11 KOS16711.1 - 4.1e-16 58.8 1.5 5.8e-16 58.3 1.0 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A Phage_GP20 PF06810.6 KOS16711.1 - 0.016 14.6 1.0 0.26 10.7 0.2 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 OEP PF02321.13 KOS16711.1 - 0.025 14.1 0.5 0.036 13.6 0.3 1.3 1 1 0 1 1 1 0 Outer membrane efflux protein DUF4398 PF14346.1 KOS16711.1 - 0.096 12.7 10.5 0.1 12.6 4.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) Seryl_tRNA_N PF02403.17 KOS16711.1 - 0.71 9.9 5.7 6.2 6.8 0.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Med9 PF07544.8 KOS16711.1 - 1.1 9.0 3.5 4.3 7.1 0.4 2.7 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.15 KOS16711.1 - 1.5 8.5 6.9 4.5 7.0 0.1 2.7 2 1 0 2 2 2 0 Prefoldin subunit DEC-1_N PF04625.8 KOS16712.1 - 0.38 9.3 2.0 0.54 8.8 1.4 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region FAD_binding_4 PF01565.18 KOS16713.1 - 1.8e-21 76.1 0.6 5.4e-21 74.5 0.4 1.9 1 0 0 1 1 1 1 FAD binding domain HET PF06985.6 KOS16714.1 - 2.8e-12 46.9 0.0 2.8e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_3 PF00933.16 KOS16716.1 - 3.6e-92 308.5 0.0 6.2e-92 307.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KOS16716.1 - 6.4e-52 176.3 0.1 4e-51 173.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KOS16716.1 - 3.4e-25 87.7 0.0 6e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_75 PF07335.6 KOS16717.1 - 1.7e-40 138.4 0.3 2.4e-40 137.9 0.2 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 LCM PF04072.9 KOS16719.1 - 2.2e-34 118.6 0.0 2.9e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase adh_short PF00106.20 KOS16720.1 - 4.1e-30 104.9 0.0 6.4e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS16720.1 - 4.1e-24 85.6 0.0 5e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS16720.1 - 6.6e-13 48.7 0.0 9.3e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KOS16720.1 - 0.00015 21.0 0.0 0.00022 20.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KOS16720.1 - 0.0026 17.5 1.2 0.0067 16.1 0.1 2.2 3 0 0 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3186 PF11382.3 KOS16720.1 - 0.045 12.8 0.1 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Polysacc_synt_2 PF02719.10 KOS16720.1 - 0.061 12.2 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_hydro_47 PF01532.15 KOS16721.1 - 6.6e-164 545.8 0.0 7.7e-164 545.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AA_permease PF00324.16 KOS16722.1 - 3.9e-138 460.7 34.1 4.7e-138 460.5 23.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KOS16722.1 - 1.2e-37 129.4 35.1 1.6e-37 129.0 24.4 1.1 1 0 0 1 1 1 1 Amino acid permease T_cell_tran_alt PF15128.1 KOS16722.1 - 0.097 12.1 0.3 5 6.6 0.0 2.7 1 1 1 2 2 2 0 T-cell leukemia translocation-altered CAP59_mtransfer PF11735.3 KOS16723.1 - 1.9e-84 282.6 0.0 2.6e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 PMT PF02366.13 KOS16724.1 - 9e-80 267.5 15.5 1.4e-79 266.9 10.7 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KOS16724.1 - 4.4e-20 72.0 1.1 8.4e-20 71.1 0.4 1.7 1 1 1 2 2 2 2 MIR domain Carb_kinase PF01256.12 KOS16726.1 - 2.6e-46 157.8 1.5 1.4e-44 152.2 1.0 2.8 1 1 0 1 1 1 1 Carbohydrate kinase DUF979 PF06166.7 KOS16726.1 - 0.064 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF979) Homeobox PF00046.24 KOS16727.1 - 4.4e-06 26.2 0.3 5.8e-06 25.8 0.2 1.1 1 0 0 1 1 1 1 Homeobox domain Cut8_N PF14482.1 KOS16727.1 - 0.083 12.9 0.5 0.093 12.7 0.3 1.3 1 0 0 1 1 1 0 Cut8 proteasome-binding domain NAD_kinase PF01513.16 KOS16728.1 - 4.7e-69 232.3 0.0 5.9e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.16 KOS16729.1 - 4e-12 46.5 0.0 6.6e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PTPA PF03095.10 KOS16730.1 - 4.4e-99 331.4 0.0 5.3e-99 331.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein NuA4 PF09340.5 KOS16731.1 - 3.8e-23 80.9 0.7 6.4e-23 80.1 0.0 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 TP2 PF01254.13 KOS16731.1 - 0.22 11.8 7.3 0.47 10.8 5.1 1.5 1 0 0 1 1 1 0 Nuclear transition protein 2 PWI PF01480.12 KOS16732.1 - 5.6e-30 103.2 0.0 9.7e-30 102.5 0.0 1.4 1 0 0 1 1 1 1 PWI domain PDZ_2 PF13180.1 KOS16733.1 - 0.00014 21.6 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KOS16733.1 - 0.0036 17.4 0.0 0.0063 16.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) RRM_1 PF00076.17 KOS16733.1 - 0.0047 16.5 0.0 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF357 PF04010.8 KOS16733.1 - 0.15 11.7 0.1 2.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF357) Ras PF00071.17 KOS16734.1 - 1.8e-49 167.2 0.1 2.2e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS16734.1 - 1.8e-16 60.6 0.0 3.1e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS16734.1 - 2.1e-11 43.3 0.0 2.9e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 KOS16734.1 - 3.1e-05 24.0 0.1 0.0013 18.8 0.1 2.3 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 KOS16734.1 - 0.00041 19.5 0.0 0.0005 19.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KOS16734.1 - 0.0028 16.3 1.6 1.6 7.3 0.0 3.0 2 1 1 3 3 3 1 G-protein alpha subunit SRPRB PF09439.5 KOS16734.1 - 0.019 14.1 0.0 0.032 13.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 KOS16734.1 - 0.033 14.0 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 KOS16734.1 - 0.045 13.0 0.1 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein MMR_HSR1 PF01926.18 KOS16734.1 - 0.052 13.5 0.1 0.08 12.9 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 KOS16734.1 - 0.059 13.5 0.2 0.27 11.3 0.1 1.9 1 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KOS16734.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 KOS16734.1 - 0.1 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KOS16734.1 - 0.12 11.4 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 KaiC Lipase_3 PF01764.20 KOS16735.1 - 2.3e-06 27.2 0.0 4.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KOS16735.1 - 0.0015 18.2 0.1 0.0047 16.6 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 KOS16735.1 - 0.062 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) adh_short_C2 PF13561.1 KOS16735.1 - 0.089 12.5 0.0 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase YL1 PF05764.8 KOS16736.1 - 1.8e-55 188.1 22.1 1.8e-55 188.1 15.3 3.2 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 KOS16736.1 - 1.2e-15 56.6 0.2 1.9e-15 56.0 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Vezatin PF12632.2 KOS16737.1 - 5.3e-46 156.7 0.0 8.3e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes HAMP PF00672.20 KOS16737.1 - 1.5 9.0 7.2 3.8 7.7 4.3 2.2 1 1 1 2 2 2 0 HAMP domain PCNA_N PF00705.13 KOS16738.1 - 6.3e-53 177.6 3.1 1.3e-52 176.5 2.1 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KOS16738.1 - 8.3e-51 171.2 0.1 1.2e-49 167.5 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KOS16738.1 - 6e-09 35.3 0.0 7.3e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 KOS16738.1 - 0.0001 21.3 0.3 0.00059 18.8 0.2 2.1 1 1 0 1 1 1 1 Hus1-like protein DNA_pol3_beta_3 PF02768.10 KOS16738.1 - 0.01 15.4 0.0 0.28 10.7 0.0 2.6 2 1 0 2 2 2 1 DNA polymerase III beta subunit, C-terminal domain DUF904 PF06005.7 KOS16739.1 - 0.0012 19.0 8.6 0.31 11.3 0.1 3.8 3 0 0 3 3 3 2 Protein of unknown function (DUF904) EMP24_GP25L PF01105.19 KOS16739.1 - 0.013 15.2 1.0 0.046 13.4 0.1 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Gryzun PF07919.7 KOS16739.1 - 0.063 11.5 0.1 0.097 10.9 0.0 1.2 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi DivIC PF04977.10 KOS16739.1 - 0.1 12.0 15.9 0.12 11.9 0.9 3.7 2 1 1 3 3 3 0 Septum formation initiator Syntaxin-6_N PF09177.6 KOS16739.1 - 0.11 12.9 3.5 0.22 11.9 0.2 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Shugoshin_N PF07558.6 KOS16739.1 - 0.19 11.4 4.7 0.3 10.8 0.3 3.0 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region Viral_P18 PF04521.8 KOS16739.1 - 0.2 11.1 4.8 2 7.8 0.3 2.8 2 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Fib_alpha PF08702.5 KOS16739.1 - 0.22 11.6 10.8 0.21 11.7 3.2 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Spc24 PF08286.6 KOS16739.1 - 0.24 11.0 4.1 7.6 6.2 0.4 3.0 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.7 KOS16739.1 - 0.24 11.6 2.6 38 4.6 1.8 3.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.3 KOS16739.1 - 0.27 11.1 17.3 1.1 9.1 3.9 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 KOS16739.1 - 0.46 10.3 18.3 0.46 10.3 1.6 3.6 3 1 1 4 4 3 0 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KOS16739.1 - 0.81 8.8 3.8 1.8 7.7 2.6 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 KOS16739.1 - 0.84 9.4 8.4 0.67 9.7 0.8 2.6 2 0 0 2 2 2 0 Tropomyosin like bZIP_1 PF00170.16 KOS16739.1 - 1.2 9.1 15.1 0.084 12.8 0.9 3.5 3 0 0 3 3 3 0 bZIP transcription factor TSC22 PF01166.13 KOS16739.1 - 1.8 8.5 6.6 4.4 7.3 0.1 3.5 3 1 0 3 3 3 0 TSC-22/dip/bun family GrpE PF01025.14 KOS16739.1 - 3 7.3 10.1 1.2 8.6 0.3 3.1 3 0 0 3 3 3 0 GrpE ATG16 PF08614.6 KOS16739.1 - 3.4 7.4 16.6 11 5.7 9.1 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) CENP-H PF05837.7 KOS16739.1 - 4.3 7.5 8.1 28 4.9 2.1 2.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Atg14 PF10186.4 KOS16739.1 - 7.3 5.4 11.4 29 3.4 7.8 2.0 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 KOS16739.1 - 9 6.3 13.8 4.8 7.2 2.0 2.8 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain Cas_Csd1 PF09709.5 KOS16740.1 - 0.042 12.1 0.1 3.1 5.9 0.0 2.4 2 1 0 2 2 2 0 CRISPR-associated protein (Cas_Csd1) DUF1460 PF07313.7 KOS16740.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) DUF834 PF05754.9 KOS16741.1 - 0.011 15.4 0.2 0.025 14.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF834) Phos_pyr_kin PF08543.7 KOS16745.1 - 4.8e-10 39.0 0.0 7.9e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KOS16745.1 - 2.5e-08 33.4 0.0 1.1e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase CENP-K PF11802.3 KOS16746.1 - 1.1e-06 28.1 0.4 0.0099 15.1 0.0 2.9 2 1 0 2 2 2 2 Centromere-associated protein K RNase_H2-Ydr279 PF09468.5 KOS16746.1 - 1.3 8.1 7.5 5.3 6.1 0.9 2.4 2 1 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) T2SM_b PF10741.4 KOS16746.1 - 2 8.0 7.6 0.18 11.4 0.9 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b TMF_DNA_bd PF12329.3 KOS16746.1 - 2.9 7.7 14.6 0.047 13.5 1.7 3.3 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.15 KOS16746.1 - 3.9 7.2 15.2 0.11 12.2 2.0 3.1 3 0 0 3 3 3 0 Prefoldin subunit DUF948 PF06103.6 KOS16746.1 - 7.2 6.5 5.6 1.6 8.6 0.4 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DEAD PF00270.24 KOS16747.1 - 1.4e-20 73.4 0.0 3.6e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KOS16747.1 - 2.3e-20 73.2 0.1 1.2e-19 70.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KOS16747.1 - 2.7e-20 71.9 0.2 7.3e-20 70.6 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SR-25 PF10500.4 KOS16747.1 - 8.2e-05 22.1 5.1 8.2e-05 22.1 3.5 3.5 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein AAA_22 PF13401.1 KOS16747.1 - 0.0004 20.5 0.0 0.0019 18.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain DUF2075 PF09848.4 KOS16747.1 - 0.024 13.5 0.2 0.082 11.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) BLVR PF06375.6 KOS16747.1 - 0.32 10.8 18.9 0.41 10.4 1.3 3.6 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) LSM PF01423.17 KOS16748.1 - 1.6e-14 53.1 0.5 2.1e-14 52.7 0.3 1.1 1 0 0 1 1 1 1 LSM domain Dodecin PF07311.7 KOS16749.1 - 0.1 12.6 0.0 0.32 11.0 0.1 1.7 2 0 0 2 2 2 0 Dodecin Amb_V_allergen PF03913.8 KOS16749.1 - 4.1 7.2 7.0 12 5.6 0.4 2.4 2 0 0 2 2 2 0 Amb V Allergen Ribosomal_L30_N PF08079.7 KOS16751.1 - 7.5e-24 83.5 19.6 1.3e-23 82.8 13.6 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KOS16751.1 - 1.1e-19 69.7 3.3 1.1e-19 69.7 0.9 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DNA_pol_viral_C PF00336.13 KOS16751.1 - 0.075 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain PEX11 PF05648.9 KOS16752.1 - 0.0017 17.6 5.5 0.027 13.7 0.2 2.9 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) eIF-3c_N PF05470.7 KOS16753.1 - 8.7e-171 569.0 21.4 8.7e-171 569.0 14.9 3.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KOS16753.1 - 4.5e-14 52.6 0.4 3.7e-13 49.6 0.0 2.6 2 0 0 2 2 2 1 PCI domain Ssu72 PF04722.8 KOS16753.1 - 0.053 12.8 2.2 0.59 9.4 0.1 2.4 2 0 0 2 2 2 0 Ssu72-like protein ApbA_C PF08546.6 KOS16754.1 - 5e-26 91.1 0.0 9.1e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KOS16754.1 - 1.2e-19 70.2 0.0 2.2e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA PROCN PF08083.6 KOS16755.1 - 6.4e-222 736.2 7.6 1.2e-221 735.4 5.2 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KOS16755.1 - 8.8e-125 414.5 1.3 1.6e-124 413.7 0.9 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KOS16755.1 - 1.2e-93 310.7 0.9 2.8e-93 309.5 0.6 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KOS16755.1 - 9.4e-76 252.6 4.6 1.4e-75 252.1 2.3 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KOS16755.1 - 2e-66 221.6 0.1 4e-66 220.7 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 KOS16755.1 - 1.6e-43 146.5 0.1 4.6e-43 144.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 KOS16755.1 - 1.6e-42 144.1 0.0 4.6e-42 142.6 0.0 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain OCD_Mu_crystall PF02423.10 KOS16755.1 - 0.24 10.1 1.5 0.42 9.3 1.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Ribosomal_S11 PF00411.14 KOS16756.1 - 2e-40 137.3 0.5 2.5e-40 137.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 KOS16756.1 - 0.014 14.2 0.0 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) SNF2_N PF00176.18 KOS16757.1 - 1.3e-71 240.8 0.0 1.8e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS16757.1 - 3.5e-13 49.2 0.0 7.7e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS16757.1 - 0.00058 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KOS16757.1 - 0.0062 16.0 0.0 0.026 14.0 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase PALP PF00291.20 KOS16758.1 - 1.2e-31 110.1 0.7 1.5e-31 109.7 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 KOS16758.1 - 0.036 12.9 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 LytB protein MFS_1 PF07690.11 KOS16759.1 - 1e-28 100.1 13.0 1.6e-28 99.4 9.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS16759.1 - 2.6e-07 29.6 6.1 1.1e-06 27.5 4.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KOS16759.1 - 0.0015 16.8 1.5 0.0024 16.1 1.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KOS16759.1 - 0.011 14.1 15.3 0.0094 14.3 2.8 3.0 1 1 2 3 3 3 0 MFS/sugar transport protein AA_permease PF00324.16 KOS16760.1 - 6.8e-121 403.9 31.3 7.7e-121 403.7 21.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KOS16760.1 - 3.3e-31 108.2 36.2 3.8e-31 108.0 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1860 PF08949.5 KOS16760.1 - 0.062 12.8 3.3 0.097 12.2 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1860) Peptidase_S8 PF00082.17 KOS16761.1 - 8.4e-36 123.5 7.4 8.4e-36 123.5 5.1 1.4 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 KOS16761.1 - 2e-12 47.5 0.2 7.7e-12 45.6 0.0 2.1 2 0 0 2 2 2 1 Peptidase inhibitor I9 Abhydrolase_3 PF07859.8 KOS16762.1 - 4.8e-37 127.6 0.0 6.2e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS16762.1 - 5.4e-06 26.2 0.0 2.2e-05 24.2 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KOS16762.1 - 0.0053 15.4 0.0 0.0067 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 KOS16762.1 - 0.044 12.5 0.0 0.056 12.1 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family Pro-kuma_activ PF09286.6 KOS16763.1 - 7.9e-48 162.1 0.0 1.4e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KOS16763.1 - 2.3e-05 23.6 2.5 4e-05 22.9 1.7 1.3 1 0 0 1 1 1 1 Subtilase family CAP_N PF01213.14 KOS16765.1 - 2 7.5 3.7 3 7.0 2.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Paf67 PF10255.4 KOS16766.1 - 2.2e-153 510.9 0.8 2.6e-153 510.6 0.6 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 KOS16766.1 - 0.038 13.8 0.0 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Usp PF00582.21 KOS16767.1 - 8.5e-15 55.1 0.2 9e-14 51.8 0.0 2.3 2 0 0 2 2 2 1 Universal stress protein family PGA2 PF07543.7 KOS16767.1 - 0.48 10.2 6.8 0.29 10.9 0.8 2.9 3 0 0 3 3 3 0 Protein trafficking PGA2 ABA_GPCR PF12430.3 KOS16768.1 - 2.1e-41 141.2 0.0 4.7e-41 140.0 0.0 1.6 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KOS16768.1 - 6.6e-17 61.3 0.0 2.2e-16 59.6 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) NUDIX PF00293.23 KOS16769.1 - 8.8e-14 51.2 0.4 1.7e-11 43.8 0.1 2.2 2 0 0 2 2 2 2 NUDIX domain RRM_1 PF00076.17 KOS16770.1 - 1.9e-12 46.5 0.0 3.6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16770.1 - 2e-10 40.5 0.0 3.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16770.1 - 0.00011 21.9 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATG16 PF08614.6 KOS16771.1 - 4.2e-42 144.1 18.1 4.7e-42 144.0 12.6 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Filament PF00038.16 KOS16771.1 - 0.0012 18.3 11.2 0.016 14.6 8.9 1.8 2 0 0 2 2 2 1 Intermediate filament protein Myosin_tail_1 PF01576.14 KOS16771.1 - 0.0034 15.1 18.7 0.0056 14.4 13.0 1.2 1 0 0 1 1 1 1 Myosin tail CCDC144C PF14915.1 KOS16771.1 - 0.023 13.6 16.5 0.16 10.8 9.6 2.0 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region DUF3584 PF12128.3 KOS16771.1 - 0.033 11.5 12.5 0.045 11.1 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SurA_N PF09312.6 KOS16771.1 - 0.036 13.9 4.0 0.034 14.0 1.7 1.7 2 0 0 2 2 2 0 SurA N-terminal domain DUF4201 PF13870.1 KOS16771.1 - 0.15 11.4 16.4 0.035 13.5 9.0 1.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) APG6 PF04111.7 KOS16771.1 - 0.38 9.7 15.4 0.13 11.2 8.7 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 Spc7 PF08317.6 KOS16771.1 - 0.48 9.0 11.2 0.83 8.2 7.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-C4H2 PF10146.4 KOS16771.1 - 0.52 10.2 8.9 0.86 9.5 6.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein ORF6C PF10552.4 KOS16771.1 - 1.2 8.8 5.8 5.5 6.7 0.2 2.3 1 1 1 2 2 2 0 ORF6C domain GAS PF13851.1 KOS16771.1 - 1.4 8.0 17.8 0.34 10.0 3.7 2.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 KOS16771.1 - 1.7 6.4 9.6 2 6.1 6.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 KOS16771.1 - 2 7.4 8.0 7 5.7 0.8 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein HAUS-augmin3 PF14932.1 KOS16771.1 - 2.5 7.2 11.8 4.4 6.4 8.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 YlqD PF11068.3 KOS16771.1 - 3.1 7.8 10.4 2.4 8.2 5.8 2.0 2 1 0 2 2 2 0 YlqD protein DUF1664 PF07889.7 KOS16771.1 - 4.1 7.2 6.1 2.2 8.1 2.9 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) SlyX PF04102.7 KOS16771.1 - 4.6 7.6 11.5 1.9 8.9 1.5 3.5 2 1 2 4 4 4 0 SlyX DUF4140 PF13600.1 KOS16771.1 - 6.5 7.2 18.1 11 6.5 0.1 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Uds1 PF15456.1 KOS16771.1 - 7.7 6.5 16.5 0.59 10.1 6.5 2.4 1 1 2 3 3 3 0 Up-regulated During Septation DivIVA PF05103.8 KOS16771.1 - 8.1 6.5 13.4 3.9 7.5 5.6 2.6 2 1 1 3 3 3 0 DivIVA protein FlxA PF14282.1 KOS16771.1 - 9.8 6.1 11.7 14 5.6 4.6 2.4 1 1 1 2 2 2 0 FlxA-like protein DOT1 PF08123.8 KOS16772.1 - 2.4e-74 249.0 0.4 6.1e-74 247.7 0.2 1.7 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 KOS16772.1 - 0.00012 21.6 0.1 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS16772.1 - 0.00017 21.6 0.0 0.00044 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS16772.1 - 0.016 15.7 0.2 0.064 13.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Proteasome PF00227.21 KOS16773.1 - 7.4e-46 155.8 0.0 5.6e-31 107.3 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KOS16773.1 - 3.8e-10 38.8 0.6 5.6e-10 38.3 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF202 PF02656.10 KOS16775.1 - 0.00011 22.3 9.6 0.00014 22.0 2.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF202) DUF4282 PF14110.1 KOS16775.1 - 0.26 11.5 2.8 0.39 10.9 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) Abhydrolase_6 PF12697.2 KOS16776.1 - 4.7e-20 72.4 4.6 7.4e-20 71.8 3.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS16776.1 - 6.5e-11 42.1 0.3 1.1e-10 41.4 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS16776.1 - 3.1e-05 23.6 0.1 0.00044 19.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KOS16776.1 - 0.0023 17.7 0.4 0.014 15.2 0.1 2.2 2 0 0 2 2 2 1 TAP-like protein Lipase_3 PF01764.20 KOS16776.1 - 0.057 13.0 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) MG1 PF11974.3 KOS16776.1 - 0.09 13.3 0.1 0.2 12.2 0.1 1.6 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain DLH PF01738.13 KOS16776.1 - 0.12 11.6 0.0 1.9 7.7 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family CFEM PF05730.6 KOS16777.1 - 8.6e-14 51.1 12.2 1.5e-13 50.3 8.5 1.4 1 0 0 1 1 1 1 CFEM domain Flu_PA PF00603.12 KOS16777.1 - 0.025 12.6 0.3 0.031 12.3 0.2 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PA DUF2108 PF09881.4 KOS16777.1 - 7 6.5 6.7 0.36 10.6 0.6 1.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2108) Ribul_P_3_epim PF00834.14 KOS16778.1 - 1.2e-59 200.8 0.0 1.3e-58 197.4 0.0 2.3 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 KOS16778.1 - 0.0049 16.3 0.1 0.014 14.8 0.1 1.7 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family HET PF06985.6 KOS16779.1 - 4.5e-20 72.2 0.4 7.4e-20 71.5 0.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) VPS9 PF02204.13 KOS16780.1 - 4.8e-20 71.5 0.0 8.6e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KOS16780.1 - 6.9e-09 35.0 0.1 8.2e-08 31.5 0.0 2.3 2 0 0 2 2 2 1 CUE domain Pol_alpha_B_N PF08418.5 KOS16780.1 - 0.0034 16.9 3.4 0.0034 16.9 2.3 3.2 3 1 1 4 4 4 1 DNA polymerase alpha subunit B N-terminal TRP PF06011.7 KOS16781.1 - 9.2e-119 396.8 14.2 1.2e-118 396.4 9.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KOS16781.1 - 7.5e-33 113.5 1.3 1.3e-32 112.7 0.9 1.4 1 0 0 1 1 1 1 ML-like domain zf-C2H2 PF00096.21 KOS16782.1 - 1.7e-06 28.0 20.3 0.00034 20.7 0.2 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS16782.1 - 0.0033 17.6 21.1 0.0092 16.2 0.2 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KOS16782.1 - 0.086 12.7 0.0 0.086 12.7 0.0 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KOS16782.1 - 0.8 9.8 9.0 0.12 12.5 1.5 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) His_Phos_2 PF00328.17 KOS16782.1 - 1.6 7.9 5.6 1.3 8.2 1.9 1.9 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 2) TPR_11 PF13414.1 KOS16783.1 - 0.05 13.2 0.0 0.84 9.3 0.0 2.8 3 0 0 3 3 3 0 TPR repeat Sod_Cu PF00080.15 KOS16784.1 - 1.4e-13 51.2 0.0 1.9e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Med3 PF11593.3 KOS16784.1 - 1.1 8.3 7.2 1.4 8.0 5.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SR-25 PF10500.4 KOS16784.1 - 9.7 5.5 15.2 13 5.2 10.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mito_fiss_reg PF05308.6 KOS16786.1 - 0.0038 16.6 3.6 0.0092 15.3 2.5 1.6 1 0 0 1 1 1 1 Mitochondrial fission regulator Glyco_transf_90 PF05686.7 KOS16787.1 - 3.6e-06 25.9 0.6 0.007 15.1 0.0 3.5 3 1 0 3 3 3 2 Glycosyl transferase family 90 TMEM171 PF15471.1 KOS16787.1 - 1.8 7.2 3.9 3.2 6.4 2.7 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 p450 PF00067.17 KOS16789.1 - 1.4e-75 254.5 0.0 1.9e-75 254.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cullin PF00888.17 KOS16791.1 - 1.5e-47 162.4 0.0 2.6e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 KOS16791.1 - 1.6e-16 60.3 0.0 2.9e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Pex14_N PF04695.8 KOS16791.1 - 0.35 10.9 13.1 0.94 9.5 0.0 3.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkr1 PF08636.5 KOS16793.1 - 8.7e-31 105.8 7.5 1.4e-30 105.1 5.2 1.3 1 0 0 1 1 1 1 ER protein Pkr1 Dicty_REP PF05086.7 KOS16793.1 - 1 7.0 2.9 1.1 6.9 2.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-C2H2_4 PF13894.1 KOS16794.1 - 0.00058 20.0 4.6 0.15 12.4 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KOS16794.1 - 0.00059 20.0 4.1 0.14 12.5 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KOS16794.1 - 0.0089 16.2 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KOS16794.1 - 0.013 15.3 2.3 3 7.8 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.1 KOS16794.1 - 0.016 14.3 0.3 0.032 13.4 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KOS16794.1 - 0.1 12.2 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-TFIIB PF13453.1 KOS16794.1 - 0.11 11.7 0.3 0.25 10.5 0.2 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger zinc_ribbon_4 PF13717.1 KOS16794.1 - 0.11 12.1 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Telomerase_RBD PF12009.3 KOS16795.1 - 6.5e-42 142.6 0.6 1.2e-41 141.7 0.4 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KOS16795.1 - 6.1e-16 58.4 0.1 2.4e-15 56.4 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NHL PF01436.16 KOS16795.1 - 0.083 12.8 0.1 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 NHL repeat RhoGEF PF00621.15 KOS16796.1 - 2.1e-35 122.2 0.3 2.1e-35 122.2 0.2 2.1 2 1 1 3 3 3 1 RhoGEF domain BAR PF03114.13 KOS16796.1 - 3.5e-08 33.2 0.9 1.7e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 BAR domain DNA_pol3_chi PF04364.8 KOS16797.1 - 0.032 14.0 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC zf-HYPF PF07503.7 KOS16797.1 - 0.055 12.8 1.9 2 7.8 0.3 2.5 2 0 0 2 2 2 0 HypF finger DUF605 PF04652.11 KOS16797.1 - 0.4 10.0 8.6 0.087 12.2 4.0 1.4 2 0 0 2 2 2 0 Vta1 like MBOAT_2 PF13813.1 KOS16798.1 - 2.2e-13 50.0 7.6 2.3e-13 49.9 3.8 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family HI0933_like PF03486.9 KOS16799.1 - 0.0037 15.8 0.3 0.31 9.4 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 KOS16799.1 - 0.0041 17.1 6.4 0.021 14.8 1.9 3.4 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KOS16799.1 - 0.021 13.9 2.5 0.038 13.0 0.0 2.2 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KOS16799.1 - 0.089 12.8 1.0 0.14 12.1 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KOS16799.1 - 0.83 8.4 6.5 0.37 9.6 0.0 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase Tyr-DNA_phospho PF06087.7 KOS16800.1 - 8.4e-12 44.4 0.0 4.7e-07 28.7 0.0 2.0 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase DUF2404 PF10296.4 KOS16801.1 - 8.6e-08 32.2 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) MBOAT PF03062.14 KOS16802.1 - 0.00063 18.9 0.1 0.00063 18.9 0.1 1.5 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family FTSW_RODA_SPOVE PF01098.14 KOS16802.1 - 0.069 11.9 0.4 0.091 11.5 0.3 1.1 1 0 0 1 1 1 0 Cell cycle protein Creatinase_N PF01321.13 KOS16803.1 - 1.5e-19 70.7 0.0 2e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain CDP-OH_P_transf PF01066.16 KOS16805.1 - 1.8e-16 60.2 5.7 1.8e-16 60.2 4.0 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Activator_LAG-3 PF11498.3 KOS16805.1 - 0.064 11.9 6.9 0.079 11.6 4.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF2489 PF10675.4 KOS16805.1 - 0.27 10.9 3.9 0.43 10.2 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) XhlA PF10779.4 KOS16805.1 - 1.5 8.8 4.0 24 4.9 1.1 2.9 3 0 0 3 3 3 0 Haemolysin XhlA GIDA PF01134.17 KOS16806.1 - 3.4e-65 220.4 0.0 4.3e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KOS16806.1 - 6.6e-17 61.3 0.0 1.7e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 GidA associated domain 3 AAA_27 PF13514.1 KOS16806.1 - 0.008 13.9 0.0 0.011 13.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain Sec1 PF00995.18 KOS16807.1 - 2.3e-116 389.6 1.6 2.8e-116 389.4 1.1 1.0 1 0 0 1 1 1 1 Sec1 family WHIM1 PF15612.1 KOS16807.1 - 0.0031 17.3 0.1 0.0092 15.8 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Methyltransf_23 PF13489.1 KOS16808.1 - 7.6e-16 58.2 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS16808.1 - 1.1e-07 32.2 0.0 9.1e-07 29.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS16808.1 - 1.3e-07 32.2 0.0 2.3e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS16808.1 - 1.8e-05 24.3 0.0 0.00014 21.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KOS16808.1 - 0.00012 22.1 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.7 KOS16808.1 - 0.00029 21.2 0.0 0.00048 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS16808.1 - 0.00074 19.5 0.0 0.0025 17.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS16808.1 - 0.0015 18.8 0.0 0.0045 17.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KOS16808.1 - 0.0087 15.1 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 KOS16808.1 - 0.02 14.0 0.0 0.18 10.8 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Fmp27 PF10344.4 KOS16809.1 - 8.4e-194 645.8 0.0 2.3e-193 644.3 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 KOS16809.1 - 1.8e-160 534.7 0.4 3.8e-160 533.6 0.3 1.6 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 KOS16809.1 - 2.1e-151 504.5 0.1 2.1e-151 504.5 0.1 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 KOS16809.1 - 2.4e-50 170.5 0.0 4.9e-50 169.4 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KOS16809.1 - 4e-50 169.6 0.1 1.2e-49 168.1 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 KOS16809.1 - 4.5e-32 110.5 0.0 1.6e-31 108.7 0.0 2.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Glyco_hydro_17 PF00332.13 KOS16810.1 - 7.3e-06 25.2 0.6 1.6e-05 24.1 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 ShlB PF03865.8 KOS16810.1 - 0.02 13.6 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB ATP-synt_10 PF05176.9 KOS16811.1 - 3.1e-83 278.9 0.0 3.9e-83 278.6 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.3 KOS16812.1 - 5.5e-13 48.7 0.1 5.5e-13 48.7 0.1 3.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus HAUS5 PF14817.1 KOS16812.1 - 0.0021 16.6 3.3 0.0032 16.0 2.0 1.5 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 5 Het-C PF07217.6 KOS16812.1 - 0.019 13.1 0.8 0.48 8.5 0.1 2.0 1 1 1 2 2 2 0 Heterokaryon incompatibility protein Het-C LXG PF04740.7 KOS16812.1 - 0.049 13.4 0.4 0.049 13.4 0.3 2.4 2 1 0 2 2 2 0 LXG domain of WXG superfamily YgaB PF14182.1 KOS16812.1 - 0.055 13.6 5.8 0.54 10.5 0.5 3.4 2 1 2 4 4 4 0 YgaB-like protein Reo_sigmaC PF04582.7 KOS16812.1 - 0.28 10.3 5.7 0.18 10.9 2.7 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF4164 PF13747.1 KOS16812.1 - 0.35 11.0 12.2 0.36 11.0 6.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Laminin_II PF06009.7 KOS16812.1 - 0.6 9.8 9.0 7.4 6.3 4.5 2.8 2 1 0 2 2 2 0 Laminin Domain II DUF4463 PF14703.1 KOS16812.1 - 1.1 9.8 3.8 2.5 8.6 2.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4463) Exonuc_VII_L PF02601.10 KOS16812.1 - 4.1 6.5 10.2 5.6 6.0 7.0 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit Ribosomal_L29 PF00831.18 KOS16813.1 - 4.1e-17 61.5 0.6 4.1e-17 61.5 0.4 1.8 2 1 0 2 2 2 1 Ribosomal L29 protein DUF896 PF05979.7 KOS16813.1 - 0.07 12.7 0.3 0.17 11.5 0.2 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) HTH_29 PF13551.1 KOS16813.1 - 0.073 13.2 0.4 0.12 12.5 0.2 1.3 1 1 0 1 1 1 0 Winged helix-turn helix Ribosomal_S9 PF00380.14 KOS16813.1 - 0.1 12.8 1.9 0.12 12.6 1.3 1.2 1 0 0 1 1 1 0 Ribosomal protein S9/S16 DEAD PF00270.24 KOS16815.1 - 1.9e-45 154.4 0.0 6.7e-44 149.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS16815.1 - 4.2e-25 87.4 0.0 9.3e-25 86.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribosomal_60s PF00428.14 KOS16815.1 - 0.0029 17.9 13.0 0.0029 17.9 9.0 6.5 5 1 1 6 6 6 1 60s Acidic ribosomal protein SNF2_N PF00176.18 KOS16815.1 - 0.0064 15.3 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HCNGP PF07818.8 KOS16816.1 - 1e-18 67.1 0.0 1.5e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 HCNGP-like protein DUF3712 PF12505.3 KOS16817.1 - 1.3e-26 93.0 1.0 1.3e-26 93.0 0.7 2.7 3 1 0 3 3 3 1 Protein of unknown function (DUF3712) WBP-1 PF11669.3 KOS16817.1 - 9.5e-06 25.6 0.1 1.7e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 WW domain-binding protein 1 LEA_2 PF03168.8 KOS16817.1 - 0.00062 20.1 3.1 0.18 12.1 0.4 3.3 2 2 0 2 2 2 2 Late embryogenesis abundant protein SUR7 PF06687.7 KOS16817.1 - 0.044 13.3 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 SUR7/PalI family DUF4307 PF14155.1 KOS16817.1 - 0.048 13.4 0.6 0.099 12.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) UPF0370 PF13980.1 KOS16817.1 - 0.068 12.9 1.3 0.12 12.2 0.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) DUF805 PF05656.9 KOS16817.1 - 0.071 12.9 0.5 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF929 PF06053.6 KOS16817.1 - 0.16 11.0 2.3 0.25 10.3 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Baculo_11_kDa PF06143.6 KOS16817.1 - 0.25 10.7 3.5 0.51 9.7 2.4 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family FMN_dh PF01070.13 KOS16818.1 - 2.9e-109 365.2 1.0 3.6e-109 364.8 0.7 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KOS16818.1 - 3.6e-21 74.7 0.0 7.9e-21 73.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KOS16818.1 - 2.8e-06 26.4 0.2 0.0011 17.8 0.1 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KOS16818.1 - 3.8e-06 26.0 0.1 6.1e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KOS16818.1 - 0.078 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein ATP11 PF06644.6 KOS16818.1 - 0.098 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein HSCB_C PF07743.8 KOS16819.1 - 1.3e-12 48.0 3.1 1.3e-12 48.0 2.1 1.4 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KOS16819.1 - 3.6e-06 26.5 0.0 7.8e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1542 PF07564.6 KOS16819.1 - 0.055 13.4 1.3 0.11 12.5 0.7 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1542) Arrestin_N PF00339.24 KOS16820.1 - 1.6e-19 70.1 0.2 1.4e-17 63.8 0.0 3.0 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KOS16820.1 - 3.2e-05 24.0 0.0 0.0005 20.1 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Sugar_tr PF00083.19 KOS16821.1 - 1.7e-86 290.6 23.6 2.2e-86 290.2 16.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS16821.1 - 5.8e-22 77.8 35.1 4e-19 68.5 17.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KOS16821.1 - 0.00028 19.2 0.9 0.00028 19.2 0.6 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF401 PF04165.7 KOS16822.1 - 0.061 12.3 0.4 0.084 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF401) BNIP3 PF06553.7 KOS16822.1 - 0.093 12.1 0.7 0.14 11.4 0.5 1.3 1 0 0 1 1 1 0 BNIP3 DUF1772 PF08592.6 KOS16822.1 - 0.32 10.7 7.8 1.5 8.5 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF4149 PF13664.1 KOS16822.1 - 0.44 10.6 4.8 0.24 11.4 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Sld5 PF05916.6 KOS16823.1 - 1.8e-13 50.6 0.0 3.4e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 GINS complex protein DUF3779 PF12621.3 KOS16823.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphate metabolism protein Proteasom_Rpn13 PF04683.8 KOS16824.1 - 1.9e-23 82.3 0.0 4.9e-23 81.0 0.0 1.7 2 0 0 2 2 2 1 Proteasome complex subunit Rpn13 ubiquitin receptor L27_2 PF09045.5 KOS16824.1 - 0.0084 15.6 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 L27_2 Rootletin PF15035.1 KOS16825.1 - 0.00021 21.3 3.0 0.00048 20.1 2.1 1.7 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Snapin_Pallidin PF14712.1 KOS16825.1 - 0.022 15.0 0.2 0.055 13.7 0.2 1.6 1 0 0 1 1 1 0 Snapin/Pallidin Secretin_N_2 PF07655.8 KOS16825.1 - 0.025 14.9 0.1 0.087 13.2 0.0 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain TAFII55_N PF04658.8 KOS16826.1 - 9.8e-48 161.7 0.0 4.9e-47 159.4 0.0 1.9 2 0 0 2 2 2 1 TAFII55 protein conserved region Sigma70_ner PF04546.8 KOS16826.1 - 0.001 18.7 16.8 0.001 18.7 11.6 3.6 3 1 0 3 3 3 2 Sigma-70, non-essential region Mucin PF01456.12 KOS16826.1 - 0.44 10.3 27.0 1 9.1 18.7 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein CDC45 PF02724.9 KOS16826.1 - 2 6.3 35.9 0.0078 14.3 8.8 3.1 3 0 0 3 3 3 0 CDC45-like protein p450 PF00067.17 KOS16827.1 - 6.5e-73 245.8 0.0 7.5e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Flu_M1 PF00598.14 KOS16827.1 - 0.16 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) DUF3074 PF11274.3 KOS16828.1 - 2e-37 128.5 0.0 2.5e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Stk19 PF10494.4 KOS16829.1 - 1e-30 106.9 0.0 1.3e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DUF1860 PF08949.5 KOS16829.1 - 0.0069 16.0 1.6 0.0069 16.0 1.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1860) Sulfate_transp PF00916.15 KOS16830.1 - 2.8e-29 101.9 0.6 8.9e-22 77.3 0.1 2.6 2 0 0 2 2 2 2 Sulfate transporter family cNMP_binding PF00027.24 KOS16830.1 - 1.3e-16 60.1 0.0 2.6e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KOS16830.1 - 2.5e-11 43.0 0.0 4.4e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain Kinesin PF00225.18 KOS16832.1 - 8.6e-81 271.2 0.5 6.7e-80 268.3 0.4 2.0 1 1 0 1 1 1 1 Kinesin motor domain JAB PF01398.16 KOS16833.1 - 7.6e-30 102.9 0.0 1.1e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KOS16833.1 - 2.9e-08 33.2 0.0 5.6e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 KOS16833.1 - 0.08 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) ATP_sub_h PF10775.4 KOS16834.1 - 5.1e-23 80.5 0.2 7.7e-23 79.9 0.1 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h LTXXQ PF07813.7 KOS16836.1 - 0.05 14.0 4.4 0.13 12.6 0.0 2.5 2 0 0 2 2 2 0 LTXXQ motif family protein Cwf_Cwc_15 PF04889.7 KOS16838.1 - 0.016 14.9 4.9 0.031 13.9 3.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 KOS16838.1 - 0.39 9.1 9.4 0.68 8.3 6.5 1.3 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 KOS16838.1 - 1.4 9.2 8.6 3.6 7.9 5.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Annexin PF00191.15 KOS16840.1 - 4.3e-64 212.3 1.6 3e-18 65.4 0.0 4.2 4 0 0 4 4 4 4 Annexin Peptidase_C13 PF01650.13 KOS16840.1 - 0.059 12.6 0.1 0.09 12.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase C13 family DUF2675 PF11247.3 KOS16840.1 - 0.076 13.0 0.1 11 6.1 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2675) DUF2614 PF11023.3 KOS16843.1 - 3.1 7.6 6.4 2.6 7.8 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) CbiQ PF02361.11 KOS16843.1 - 8.5 5.8 11.9 12 5.4 8.2 1.1 1 0 0 1 1 1 0 Cobalt transport protein Abhydrolase_6 PF12697.2 KOS16844.1 - 8.8e-21 74.8 0.0 1.5e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS16844.1 - 6e-11 42.2 0.0 1.1e-10 41.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS16844.1 - 1.1e-10 41.5 0.5 3.8e-10 39.7 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KOS16844.1 - 0.00072 18.5 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 KOS16844.1 - 0.0031 17.3 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 KOS16844.1 - 0.015 14.0 0.0 0.025 13.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase PGAP1 PF07819.8 KOS16844.1 - 0.035 13.6 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF2305 PF10230.4 KOS16844.1 - 0.041 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF1057 PF06342.7 KOS16844.1 - 0.16 10.7 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) SUZ PF12752.2 KOS16847.1 - 0.0016 18.9 5.8 0.0016 18.9 4.0 4.8 5 1 0 5 5 5 2 SUZ domain RRM_5 PF13893.1 KOS16848.1 - 1.5e-11 43.9 0.0 2.3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS16848.1 - 3.6e-08 32.9 0.0 1e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16848.1 - 9.6e-05 22.2 0.0 0.0002 21.2 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KOS16848.1 - 0.00033 20.2 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.3 KOS16848.1 - 0.00041 20.0 0.3 0.00097 18.8 0.0 1.7 2 0 0 2 2 2 1 Limkain b1 TFIIA PF03153.8 KOS16848.1 - 0.0049 16.8 0.5 0.0054 16.6 0.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4523 PF15023.1 KOS16848.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) MSP1_C PF07462.6 KOS16848.1 - 4.4 5.5 5.4 5.4 5.2 3.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Autophagy_act_C PF03987.10 KOS16849.1 - 2.6e-12 46.7 0.0 5.1e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ribonuc_L-PSP PF01042.16 KOS16850.1 - 9.1e-37 125.5 0.0 1e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DAHP_synth_1 PF00793.15 KOS16851.1 - 2.9e-94 314.7 0.0 3.7e-94 314.4 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family Pro_isomerase PF00160.16 KOS16852.1 - 1.6e-50 171.3 0.1 3.1e-50 170.4 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KOS16852.1 - 1e-14 53.7 1.6 2.1e-07 30.5 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Fe_hyd_lg_C PF02906.9 KOS16853.1 - 1.1e-55 188.9 0.0 2.5e-55 187.7 0.0 1.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Myc_N PF01056.13 KOS16853.1 - 0.13 11.3 5.0 0.078 12.1 1.5 1.8 2 0 0 2 2 2 0 Myc amino-terminal region Chorion_3 PF05387.6 KOS16853.1 - 0.23 10.8 3.6 0.48 9.8 2.5 1.5 1 0 0 1 1 1 0 Chorion family 3 Ribosomal_60s PF00428.14 KOS16853.1 - 2 8.8 7.4 1.7 9.1 2.7 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-H2C2_2 PF13465.1 KOS16854.1 - 8.9e-07 28.9 10.2 5.2e-06 26.4 0.9 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KOS16854.1 - 6.5e-05 23.0 0.5 6.5e-05 23.0 0.4 3.2 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS16854.1 - 0.00025 21.1 0.4 0.00025 21.1 0.3 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KOS16854.1 - 0.16 12.1 3.4 1.3 9.2 0.4 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Daxx PF03344.10 KOS16855.1 - 0.24 9.8 18.4 0.23 9.8 12.7 1.0 1 0 0 1 1 1 0 Daxx Family Adaptin_binding PF10199.4 KOS16855.1 - 0.3 11.3 13.4 0.35 11.1 9.3 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CobT PF06213.7 KOS16855.1 - 0.62 9.1 24.3 0.73 8.9 16.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 KOS16855.1 - 0.72 9.0 19.8 0.91 8.7 13.7 1.2 1 0 0 1 1 1 0 NOA36 protein COPI_C PF06957.6 KOS16855.1 - 1.1 7.7 19.6 1.2 7.5 13.6 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus FLO_LFY PF01698.11 KOS16855.1 - 1.5 7.5 5.2 1.9 7.2 3.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2457 PF10446.4 KOS16855.1 - 1.8 7.1 32.6 2.4 6.7 22.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1510 PF07423.6 KOS16855.1 - 3.2 7.0 12.2 3.7 6.8 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CENP-T PF15511.1 KOS16855.1 - 3.4 6.8 16.7 4 6.5 11.6 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 KOS16855.1 - 3.8 6.4 18.1 4.7 6.1 12.5 1.2 1 0 0 1 1 1 0 BUD22 BTV_NS2 PF04514.7 KOS16855.1 - 8.4 5.1 9.5 9.9 4.9 6.6 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SDA1 PF05285.7 KOS16855.1 - 9 5.4 23.7 11 5.2 16.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 KOS16855.1 - 9.6 4.0 18.7 11 3.9 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Retinal PF15449.1 KOS16856.1 - 0.15 9.6 14.0 0.19 9.3 9.7 1.1 1 0 0 1 1 1 0 Retinal protein WD40 PF00400.27 KOS16857.1 - 1.9e-19 68.7 13.5 1.9e-07 30.6 0.1 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat Gmad1 PF10647.4 KOS16857.1 - 0.052 12.9 4.4 0.072 12.4 0.1 2.8 2 2 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Rax2 PF12768.2 KOS16857.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Isy1 PF06246.7 KOS16858.1 - 4.9e-84 281.7 0.1 9.2e-84 280.8 0.1 1.4 1 1 0 1 1 1 1 Isy1-like splicing family Ufd2P_core PF10408.4 KOS16858.1 - 0.15 10.2 0.2 0.21 9.7 0.2 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core DDOST_48kD PF03345.9 KOS16859.1 - 3.4e-155 516.7 0.0 3.8e-155 516.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta TIR_2 PF13676.1 KOS16859.1 - 0.038 14.1 0.1 0.091 12.9 0.1 1.6 1 0 0 1 1 1 0 TIR domain DUF3433 PF11915.3 KOS16859.1 - 0.085 13.0 0.3 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) NADHdh_A3 PF14987.1 KOS16860.1 - 0.04 13.8 1.5 0.042 13.7 0.8 1.3 1 1 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Beach PF02138.13 KOS16861.1 - 2e-108 361.9 0.0 3.3e-108 361.2 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.1 KOS16861.1 - 1.5e-11 44.7 0.1 3.2e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.1 KOS16861.1 - 5.2e-11 42.3 0.0 1.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 KOS16861.1 - 1.7e-09 37.2 7.5 0.00069 19.4 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Peptidase_S8 PF00082.17 KOS16862.1 - 6.6e-50 169.8 8.0 1e-49 169.1 5.6 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KOS16862.1 - 1.9e-21 76.3 0.2 4.1e-21 75.3 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 PAF-AH_p_II PF03403.8 KOS16863.1 - 5.2e-25 87.5 0.0 1.3e-23 82.9 0.0 2.8 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KOS16863.1 - 2.7e-10 40.1 0.2 6.6e-10 38.9 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KOS16863.1 - 0.005 15.7 0.0 0.21 10.4 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KOS16863.1 - 0.083 11.6 0.0 0.18 10.5 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase COX17 PF05051.8 KOS16865.1 - 4e-20 71.5 5.3 4.7e-20 71.3 3.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DUF914 PF06027.7 KOS16866.1 - 1.7e-101 339.4 8.2 2.2e-101 339.0 5.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KOS16866.1 - 2.8e-05 24.1 27.2 0.00027 20.9 4.6 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 KOS16866.1 - 0.02 14.5 16.1 0.45 10.1 0.5 2.4 2 0 0 2 2 2 0 Triose-phosphate Transporter family UAA PF08449.6 KOS16866.1 - 0.44 9.4 9.6 1.2 8.0 6.6 1.7 1 1 0 1 1 1 0 UAA transporter family Cpn60_TCP1 PF00118.19 KOS16868.1 - 3.7e-138 461.1 13.0 4.6e-138 460.8 9.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 KOS16868.1 - 0.039 13.4 0.1 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Phage Tail Protein X V-ATPase_G PF03179.10 KOS16869.1 - 0.021 15.0 5.8 0.033 14.4 4.0 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Mt_ATP-synt_B PF05405.9 KOS16869.1 - 0.025 14.0 5.1 0.05 13.0 3.5 1.4 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF849 PF05853.7 KOS16869.1 - 0.027 13.3 0.4 0.031 13.1 0.3 1.3 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) DUF2352 PF09817.4 KOS16869.1 - 0.051 11.7 1.1 0.057 11.5 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2352) EcoRI PF02963.11 KOS16869.1 - 0.094 11.4 0.2 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease EcoRI UBN2 PF14223.1 KOS16869.1 - 0.19 11.5 3.5 0.61 9.8 0.6 2.0 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type Muted PF14942.1 KOS16869.1 - 0.41 10.5 7.4 0.56 10.0 5.1 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein GvpL_GvpF PF06386.6 KOS16869.1 - 0.56 9.7 6.2 0.61 9.6 4.3 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF2533 PF10752.4 KOS16869.1 - 1.2 9.5 5.6 2.9 8.2 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2533) Atg14 PF10186.4 KOS16869.1 - 1.8 7.4 5.5 2 7.2 3.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 KOS16869.1 - 2.4 6.4 11.8 2.7 6.3 8.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3391 PF11871.3 KOS16869.1 - 5.6 7.1 9.5 7.9 6.7 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) AAA PF00004.24 KOS16871.1 - 2.6e-40 137.6 0.0 4.3e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS16871.1 - 4.9e-06 26.7 0.0 0.0006 19.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KOS16871.1 - 2.9e-05 23.8 0.1 0.00024 20.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KOS16871.1 - 0.00036 20.5 0.0 0.0031 17.5 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 KOS16871.1 - 0.00062 19.7 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KOS16871.1 - 0.0022 16.9 0.0 0.0038 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KOS16871.1 - 0.0048 17.7 0.1 0.013 16.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KOS16871.1 - 0.0093 15.0 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KOS16871.1 - 0.0099 15.7 0.0 0.025 14.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KOS16871.1 - 0.01 15.5 0.2 0.022 14.5 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 KOS16871.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KOS16871.1 - 0.03 13.9 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KOS16871.1 - 0.03 14.4 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 KOS16871.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KOS16871.1 - 0.054 13.0 0.1 0.6 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KOS16871.1 - 0.071 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 KOS16871.1 - 0.085 12.9 0.0 0.19 11.7 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 KOS16871.1 - 0.1 12.8 0.1 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KOS16871.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein BNR_2 PF13088.1 KOS16873.1 - 2e-11 43.7 1.2 0.029 13.6 0.0 5.4 4 2 1 5 5 5 4 BNR repeat-like domain BNR PF02012.15 KOS16873.1 - 1e-06 27.6 48.1 1.5 8.9 0.1 12.1 12 0 0 12 12 12 7 BNR/Asp-box repeat PSII_BNR PF14870.1 KOS16873.1 - 0.0044 16.0 2.1 1.9 7.4 0.0 4.1 4 1 1 5 5 5 2 Photosynthesis system II assembly factor YCF48 DUF2561 PF10812.3 KOS16873.1 - 0.016 14.7 0.2 0.03 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) HLH PF00010.21 KOS16875.1 - 2.2e-10 40.0 0.1 5e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 KOS16875.1 - 0.013 15.4 1.3 0.033 14.1 0.9 1.6 1 0 0 1 1 1 0 bZIP transcription factor Herpes_UL74 PF07982.7 KOS16875.1 - 0.85 8.2 5.3 1.6 7.3 3.7 1.3 1 0 0 1 1 1 0 Herpes UL74 glycoproteins Pcc1 PF09341.5 KOS16876.1 - 5.9e-25 87.1 0.0 7.8e-25 86.7 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.1 KOS16877.1 - 4e-42 143.5 0.0 7.4e-40 136.1 0.0 2.9 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KOS16877.1 - 5.9e-17 61.4 0.0 1.7e-16 60.0 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KOS16877.1 - 3.7e-06 26.4 0.0 6.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pyrophosphatase PF00719.14 KOS16878.1 - 1.1e-52 177.5 0.1 1.5e-52 177.1 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase TAP_C PF03943.8 KOS16879.1 - 4e-14 51.7 0.5 7.6e-14 50.8 0.2 1.7 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.2 KOS16879.1 - 1.7e-07 30.6 0.0 4.1e-06 26.2 0.0 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) NTF2 PF02136.15 KOS16879.1 - 5.1e-05 23.6 0.0 0.0007 19.9 0.0 2.4 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_6 PF13516.1 KOS16879.1 - 0.0057 16.5 0.3 0.5 10.6 0.0 3.4 3 0 0 3 3 3 1 Leucine Rich repeat LRR_8 PF13855.1 KOS16879.1 - 0.039 13.7 0.1 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.28 KOS16879.1 - 0.16 12.1 0.0 2.6 8.4 0.0 2.7 2 0 0 2 2 2 0 Leucine Rich Repeat Sec20 PF03908.8 KOS16880.1 - 6.8e-14 51.3 0.1 4.8e-13 48.6 0.1 2.1 2 0 0 2 2 2 1 Sec20 MRP_L53 PF10780.4 KOS16881.1 - 1.5e-18 66.4 0.2 2.1e-18 65.9 0.1 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 DUF2442 PF10387.4 KOS16881.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) Ecotin PF03974.8 KOS16881.1 - 0.15 11.7 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Ecotin TRAPP PF04051.11 KOS16882.1 - 1.5e-42 144.7 0.0 2.1e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CAP_N PF01213.14 KOS16882.1 - 0.14 11.4 1.1 0.2 10.8 0.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PINIT PF14324.1 KOS16883.1 - 1.6e-31 109.3 0.0 3e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KOS16883.1 - 5.3e-21 73.8 6.9 1.1e-20 72.8 4.8 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KOS16883.1 - 1.3e-05 24.6 1.7 2.8e-05 23.5 1.2 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 KOS16883.1 - 0.11 12.4 6.2 0.23 11.3 4.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KOS16883.1 - 1.6 8.6 5.8 4.1 7.3 4.0 1.8 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.24 KOS16883.1 - 1.8 8.2 5.9 0.55 9.9 1.9 1.8 2 0 0 2 2 2 0 PHD-finger Phosphodiest PF01663.17 KOS16884.1 - 1.6e-14 53.9 0.1 2.6e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KOS16884.1 - 3.7e-05 23.0 0.0 5.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KOS16884.1 - 0.0014 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily LST1 PF05083.8 KOS16884.1 - 0.15 12.0 0.8 0.39 10.7 0.6 1.6 1 0 0 1 1 1 0 LST-1 protein DUF229 PF02995.12 KOS16884.1 - 0.29 9.5 0.0 0.4 9.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF3244 PF11589.3 KOS16885.1 - 0.059 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) DUF1675 PF07897.6 KOS16885.1 - 5 6.9 17.4 7.8 6.2 12.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Herpes_UL32 PF06070.6 KOS16885.1 - 6.3 5.1 21.6 7.3 4.9 15.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Glycophorin_A PF01102.13 KOS16886.1 - 0.0062 16.3 0.5 0.011 15.5 0.4 1.3 1 0 0 1 1 1 1 Glycophorin A P12 PF12669.2 KOS16886.1 - 0.61 10.3 5.1 4.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Virus attachment protein p12 family PRCC PF10253.4 KOS16886.1 - 0.65 10.6 4.0 1 10.0 2.8 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF3605 PF12239.3 KOS16887.1 - 1.2e-53 181.1 0.0 1.5e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Lipl32 PF12103.3 KOS16887.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order UDPGP PF01704.13 KOS16888.1 - 3.8e-185 615.3 0.1 4.4e-185 615.1 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 KOS16888.1 - 0.12 10.9 1.3 1.1 7.7 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4301) Leo1 PF04004.8 KOS16889.1 - 4.2e-31 107.9 0.0 4.2e-31 107.9 0.0 1.6 2 0 0 2 2 2 1 Leo1-like protein Mob1_phocein PF03637.12 KOS16890.1 - 4.8e-37 127.3 1.1 3.7e-19 69.0 0.0 2.2 2 0 0 2 2 2 2 Mob1/phocein family CAP59_mtransfer PF11735.3 KOS16891.1 - 2.2e-65 220.2 0.0 3e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF3336 PF11815.3 KOS16892.1 - 6.1e-35 119.8 0.5 1.8e-34 118.3 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KOS16892.1 - 1.6e-13 51.0 1.0 1.5e-12 47.8 0.2 2.3 2 0 0 2 2 2 1 Patatin-like phospholipase 7tm_2 PF00002.19 KOS16893.1 - 2.2e-05 23.6 2.3 3.4e-05 23.0 1.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 KOS16893.1 - 0.048 12.5 2.9 0.16 10.8 2.0 1.8 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor PsbT PF01405.12 KOS16893.1 - 0.19 11.3 3.4 0.59 9.7 2.3 1.9 1 0 0 1 1 1 0 Photosystem II reaction centre T protein FolB PF02152.13 KOS16894.1 - 1.3e-10 41.3 0.0 8.3e-08 32.3 0.0 3.4 3 1 0 3 3 3 1 Dihydroneopterin aldolase DUF4243 PF14027.1 KOS16895.1 - 3.8e-78 263.2 0.5 4.5e-78 262.9 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) HECT_2 PF09814.4 KOS16896.1 - 8.1e-55 185.9 0.0 1e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Lipase_GDSL_2 PF13472.1 KOS16897.1 - 1.1e-20 74.5 0.0 1.5e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KOS16897.1 - 4.7e-07 29.8 0.0 8.7e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rad17 PF03215.10 KOS16898.1 - 1.3e-52 179.2 0.0 3.1e-52 177.9 0.0 1.6 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KOS16898.1 - 0.0006 19.9 0.0 0.0019 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS16898.1 - 0.0028 18.4 0.0 0.0065 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS16898.1 - 0.0046 16.9 0.0 0.0046 16.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 KOS16898.1 - 0.0083 15.0 0.0 0.018 13.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 KOS16898.1 - 0.011 15.9 0.0 0.043 14.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KOS16898.1 - 0.013 15.4 3.0 0.016 15.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KOS16898.1 - 0.015 15.0 0.0 0.015 15.0 0.0 3.1 3 0 0 3 3 3 0 Part of AAA domain NACHT PF05729.7 KOS16898.1 - 0.034 13.8 0.0 0.082 12.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 KOS16898.1 - 0.044 13.4 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KOS16898.1 - 0.13 12.5 0.1 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.9 KOS16898.1 - 0.54 7.9 1.3 0.69 7.5 0.0 1.7 3 0 0 3 3 3 0 Helicase Neur_chan_memb PF02932.11 KOS16898.1 - 1.4 8.7 3.5 0.66 9.8 0.0 2.3 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FimP PF09766.4 KOS16898.1 - 4.6 6.2 10.6 9.8 5.1 7.3 1.5 1 0 0 1 1 1 0 Fms-interacting protein Ppx-GppA PF02541.11 KOS16900.1 - 1e-23 83.9 0.0 4e-17 62.3 0.0 2.1 2 0 0 2 2 2 2 Ppx/GppA phosphatase family LRR_4 PF12799.2 KOS16901.1 - 6.2e-08 32.0 10.1 0.00011 21.7 0.1 4.0 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) Med25_SD1 PF11235.3 KOS16901.1 - 0.0028 17.9 0.3 0.0049 17.1 0.2 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 synapsin 1 LRR_8 PF13855.1 KOS16901.1 - 0.0033 17.1 13.4 0.06 13.1 1.7 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.1 KOS16901.1 - 0.029 14.4 0.1 0.029 14.4 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.28 KOS16901.1 - 0.036 14.0 3.8 0.44 10.7 0.0 3.8 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 KOS16901.1 - 0.099 12.9 9.5 0.89 10.0 0.1 4.8 3 1 1 4 4 4 0 Leucine rich repeat zf-RING_2 PF13639.1 KOS16903.1 - 7e-07 28.9 9.3 1.3e-06 28.1 6.4 1.5 1 0 0 1 1 1 1 Ring finger domain FHA PF00498.21 KOS16903.1 - 2.2e-05 24.4 0.0 7.3e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 FHA domain zf-rbx1 PF12678.2 KOS16903.1 - 4.2e-05 23.5 3.7 8.6e-05 22.5 2.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KOS16903.1 - 0.0036 16.9 9.3 0.0072 15.9 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KOS16903.1 - 0.0052 16.4 3.9 0.01 15.4 2.7 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 KOS16903.1 - 0.026 14.6 0.5 0.053 13.6 0.4 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.1 KOS16903.1 - 0.04 13.6 6.9 0.076 12.7 4.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-TFIIIC PF12660.2 KOS16903.1 - 0.1 12.5 2.1 0.18 11.7 1.4 1.3 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex zf-RING-like PF08746.6 KOS16903.1 - 0.13 12.3 4.7 0.23 11.4 3.2 1.4 1 0 0 1 1 1 0 RING-like domain zf-Apc11 PF12861.2 KOS16903.1 - 0.18 11.6 1.6 0.39 10.5 1.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KOS16903.1 - 0.39 10.7 10.7 0.73 9.9 7.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KOS16903.1 - 2.4 8.0 6.9 6.5 6.7 4.8 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Peptidase_M16_C PF05193.16 KOS16904.1 - 4.1e-47 160.2 0.0 1.3e-46 158.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KOS16904.1 - 3.3e-40 137.2 0.0 5.5e-39 133.2 0.0 2.6 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) CytochromB561_N PF09786.4 KOS16904.1 - 1.1 7.6 7.3 1.5 7.1 5.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal S1 PF00575.18 KOS16906.1 - 2.2e-95 312.7 37.8 1.6e-17 63.3 0.6 13.0 13 0 0 13 13 13 11 S1 RNA binding domain TPR_14 PF13428.1 KOS16906.1 - 4.2e-05 23.8 7.4 0.055 14.1 0.0 5.6 4 3 2 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KOS16906.1 - 0.00013 22.2 2.3 0.055 13.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KOS16906.1 - 0.00017 22.1 0.6 0.22 12.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat EXOSC1 PF10447.4 KOS16906.1 - 0.00052 19.9 14.7 23 5.0 0.0 9.8 8 3 1 9 9 9 0 Exosome component EXOSC1/CSL4 MRP-S35 PF10246.4 KOS16906.1 - 0.0078 16.1 2.2 9.4 6.2 0.0 4.6 4 0 0 4 4 4 1 Mitochondrial ribosomal protein MRP-S35 Daxx PF03344.10 KOS16906.1 - 0.011 14.2 36.7 0.006 15.1 19.2 2.6 2 0 0 2 2 2 0 Daxx Family TPR_11 PF13414.1 KOS16906.1 - 0.039 13.6 0.9 0.61 9.7 0.1 2.7 2 0 0 2 2 2 0 TPR repeat Nop14 PF04147.7 KOS16906.1 - 0.097 10.5 53.6 0.0046 14.9 28.3 2.4 2 0 0 2 2 2 0 Nop14-like family TPR_7 PF13176.1 KOS16906.1 - 0.11 12.3 0.1 0.94 9.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KOS16906.1 - 0.17 11.9 0.5 1 9.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KOS16906.1 - 0.4 10.6 1.9 1.4e+02 2.4 0.0 3.1 1 1 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.13 KOS16907.1 - 3.1e-09 36.0 0.0 4.5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MAP65_ASE1 PF03999.7 KOS16908.1 - 7.8e-73 246.0 16.3 9.6e-73 245.7 11.3 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Spectrin PF00435.16 KOS16908.1 - 0.27 11.5 12.9 0.16 12.2 1.8 4.3 5 1 0 5 5 5 0 Spectrin repeat EF-hand_4 PF12763.2 KOS16909.1 - 2.3e-05 24.0 0.0 3.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.1 KOS16909.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair IncA PF04156.9 KOS16911.1 - 0.3 10.6 2.2 0.59 9.7 1.6 1.5 1 0 0 1 1 1 0 IncA protein ATP-synt_ab PF00006.20 KOS16912.1 - 5.4e-70 235.2 0.0 7.9e-70 234.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KOS16912.1 - 5.9e-28 97.5 0.4 2.1e-27 95.8 0.3 2.0 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KOS16912.1 - 1.2e-15 57.4 2.7 2.9e-15 56.2 1.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KOS16912.1 - 0.0042 16.9 1.3 0.0093 15.8 0.7 1.8 2 0 0 2 2 2 1 HAS barrel domain Aminotran_5 PF00266.14 KOS16915.1 - 1.5e-34 119.3 0.0 4.3e-34 117.8 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V AAA_12 PF13087.1 KOS16916.1 - 2.6e-38 131.4 2.1 3e-38 131.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KOS16916.1 - 7.4e-38 129.7 0.0 3.3e-13 49.9 0.0 4.3 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS16916.1 - 7.5e-14 51.9 5.9 0.0017 18.5 0.0 6.8 4 3 0 4 4 4 3 AAA domain AAA_11 PF13086.1 KOS16916.1 - 2.3e-13 50.2 18.0 7.9e-09 35.4 0.0 6.5 5 1 0 5 5 5 2 AAA domain AAA_19 PF13245.1 KOS16916.1 - 8.2e-10 38.3 0.2 0.097 12.4 0.0 3.8 3 0 0 3 3 3 3 Part of AAA domain AAA_16 PF13191.1 KOS16916.1 - 4.3e-09 36.6 5.2 0.072 13.0 0.0 4.8 5 1 0 5 5 4 3 AAA ATPase domain AAA_5 PF07728.9 KOS16916.1 - 2.2e-08 33.8 0.4 0.085 12.5 0.0 4.1 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KOS16916.1 - 7e-08 32.2 1.5 2.3 7.7 0.0 5.4 4 2 0 4 4 4 2 AAA domain AAA_17 PF13207.1 KOS16916.1 - 7.5e-07 30.0 15.7 0.016 15.9 0.0 5.3 5 0 0 5 5 5 3 AAA domain AAA_33 PF13671.1 KOS16916.1 - 9.9e-07 28.7 0.8 0.29 11.0 0.0 3.9 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 KOS16916.1 - 1.6e-06 27.4 0.9 0.27 10.3 0.0 4.0 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KOS16916.1 - 8.4e-05 22.7 0.4 2.1 8.5 0.0 3.8 3 0 0 3 3 3 2 RNA helicase Torsin PF06309.6 KOS16916.1 - 0.00012 22.0 0.1 9.1 6.1 0.0 4.0 4 0 0 4 4 4 0 Torsin Sigma54_activ_2 PF14532.1 KOS16916.1 - 0.00021 21.3 0.3 0.14 12.2 0.0 4.1 4 0 0 4 4 4 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 KOS16916.1 - 0.00052 19.4 0.0 8.2 5.7 0.0 3.8 3 0 0 3 3 3 0 IstB-like ATP binding protein Guanylate_cyc_2 PF09778.4 KOS16916.1 - 0.0012 18.1 0.0 0.1 11.7 0.0 3.0 3 0 0 3 3 3 1 Guanylylate cyclase Sigma54_activat PF00158.21 KOS16916.1 - 0.0013 18.2 0.4 12 5.2 0.0 4.3 5 0 0 5 5 5 0 Sigma-54 interaction domain AAA_25 PF13481.1 KOS16916.1 - 0.0089 15.4 2.0 25 4.1 0.0 4.9 5 0 0 5 5 5 0 AAA domain AAA_24 PF13479.1 KOS16916.1 - 0.019 14.5 12.4 3.6 7.1 0.1 4.4 4 1 0 4 4 4 0 AAA domain AAA_18 PF13238.1 KOS16916.1 - 0.022 15.0 16.6 2.4 8.4 0.0 5.0 5 0 0 5 5 4 0 AAA domain AAA_29 PF13555.1 KOS16916.1 - 0.049 13.1 0.7 7.9 6.0 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_10 PF12846.2 KOS16916.1 - 0.073 12.5 12.8 1.2 8.5 0.1 5.3 5 1 1 6 6 5 0 AAA-like domain zf-NF-X1 PF01422.12 KOS16916.1 - 1.7 8.6 9.5 4.3 7.3 6.6 1.7 1 0 0 1 1 1 0 NF-X1 type zinc finger Fmp27_WPPW PF10359.4 KOS16916.1 - 8.7 4.6 18.0 4.3 5.6 9.5 2.3 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Abhydrolase_1 PF00561.15 KOS16918.1 - 2.4e-18 66.5 0.0 4e-17 62.5 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KOS16918.1 - 4.8e-10 39.7 16.3 6.2e-10 39.3 8.5 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 KOS16918.1 - 0.0049 16.3 0.1 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase SR-25 PF10500.4 KOS16918.1 - 0.011 15.2 8.2 0.021 14.3 5.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1275 PF06912.6 KOS16919.1 - 2.2e-43 147.9 13.8 2.7e-43 147.6 9.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2177 PF09945.4 KOS16919.1 - 0.026 14.5 1.1 0.039 13.9 0.2 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) BioY PF02632.9 KOS16919.1 - 4.5 6.9 10.7 6.7 6.3 0.7 2.4 1 1 0 2 2 2 0 BioY family DUF1043 PF06295.7 KOS16921.1 - 0.014 15.0 1.1 0.026 14.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Peptidase_M6 PF05547.6 KOS16922.1 - 4.1e-08 31.7 0.1 0.00054 18.1 0.8 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 Ribophorin_I PF04597.9 KOS16923.1 - 6e-143 476.4 0.0 6.8e-143 476.2 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Pil1 PF13805.1 KOS16924.1 - 2.9e-102 341.4 1.4 3.9e-102 341.0 1.0 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Ank_2 PF12796.2 KOS16925.1 - 5.2e-06 26.7 0.0 1.5e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Phostensin_N PF13916.1 KOS16925.1 - 0.065 13.2 2.4 0.6 10.1 0.0 2.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal SDA1 PF05285.7 KOS16925.1 - 0.26 10.5 11.5 0.43 9.7 4.2 2.1 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.7 KOS16925.1 - 1.2 6.9 6.2 1.5 6.6 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family Hexokinase_2 PF03727.11 KOS16926.1 - 9e-89 296.8 0.0 1.2e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KOS16926.1 - 8.3e-75 250.6 0.0 7.2e-74 247.5 0.0 2.0 2 0 0 2 2 2 1 Hexokinase TPP_enzyme_N PF02776.13 KOS16926.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain PhnJ PF06007.6 KOS16926.1 - 0.14 10.9 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ Vps16_N PF04841.8 KOS16927.1 - 1.6e-84 283.8 0.0 3.8e-84 282.6 0.0 1.6 2 0 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.7 KOS16927.1 - 3.5e-73 246.3 0.0 5.7e-73 245.6 0.0 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region VTC PF09359.5 KOS16928.1 - 4.6e-100 334.2 0.0 8.2e-100 333.4 0.0 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KOS16928.1 - 2.9e-24 86.3 4.2 1e-11 45.1 0.0 3.8 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 KOS16928.1 - 2.2e-12 47.0 1.2 4.6e-12 45.9 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) TrmB PF01978.14 KOS16928.1 - 0.0018 17.9 0.0 0.0069 16.0 0.1 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.1 KOS16928.1 - 0.0076 16.3 0.1 0.18 11.9 0.0 2.8 3 0 0 3 3 3 1 Winged helix-turn helix Fe_dep_repress PF01325.14 KOS16928.1 - 0.024 14.5 0.1 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Exo_endo_phos PF03372.18 KOS16929.1 - 3.9e-16 59.7 6.7 6.8e-16 58.9 4.7 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family KH_1 PF00013.24 KOS16930.1 - 8.2e-40 134.2 5.7 2.5e-16 59.0 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KOS16930.1 - 3.7e-31 106.2 12.1 4.4e-12 45.3 1.9 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KOS16930.1 - 1.6e-12 46.7 4.9 0.0028 17.1 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KOS16930.1 - 1.7e-05 24.3 1.1 0.53 9.9 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KOS16930.1 - 0.0006 19.5 7.1 0.63 9.8 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain G-patch PF01585.18 KOS16931.1 - 2.4e-05 24.0 0.0 7.8e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 G-patch domain Utp14 PF04615.8 KOS16931.1 - 0.0003 19.1 58.4 0.00038 18.7 40.5 1.2 1 0 0 1 1 1 1 Utp14 protein TFIIF_alpha PF05793.7 KOS16931.1 - 0.72 8.1 80.5 1.2 7.4 55.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF936 PF06075.7 KOS16931.1 - 4.6 6.0 46.6 6.6 5.5 32.3 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) FKBP_C PF00254.23 KOS16932.1 - 7.6e-30 102.7 0.6 3.7e-29 100.5 0.0 2.4 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase Utp14 PF04615.8 KOS16932.1 - 0.083 11.0 52.2 0.054 11.6 20.5 2.1 2 0 0 2 2 2 0 Utp14 protein Drc1-Sld2 PF11719.3 KOS16932.1 - 7.8 5.4 37.6 0.28 10.2 5.9 2.2 2 0 0 2 2 2 0 DNA replication and checkpoint protein DUF1746 PF08508.5 KOS16933.1 - 6.3e-34 116.3 1.7 9.3e-34 115.8 1.2 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) PGA2 PF07543.7 KOS16933.1 - 0.3 10.8 3.2 0.51 10.1 2.2 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 RTC PF01137.16 KOS16934.1 - 4.4e-31 107.4 0.1 7e-31 106.7 0.1 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KOS16934.1 - 2.4e-28 98.1 0.1 4.3e-28 97.3 0.1 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PPR_2 PF13041.1 KOS16935.1 - 5.6e-08 32.6 0.2 0.0001 22.1 0.0 4.4 5 0 0 5 5 5 1 PPR repeat family PPR_3 PF13812.1 KOS16935.1 - 0.0022 18.1 6.4 4.1 7.9 0.0 6.3 6 0 0 6 6 6 1 Pentatricopeptide repeat domain NYD-SP28 PF14772.1 KOS16935.1 - 1.2 9.2 11.2 1.5 8.9 0.1 2.7 2 0 0 2 2 2 0 Sperm tail Peptidase_S9 PF00326.16 KOS16937.1 - 3.4e-58 196.3 0.1 6.3e-58 195.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KOS16937.1 - 1.2e-12 47.8 0.0 2.2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS16937.1 - 2.8e-11 43.7 0.1 8.2e-11 42.2 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KOS16937.1 - 0.00041 19.8 0.6 0.0009 18.7 0.4 1.5 1 0 0 1 1 1 1 Putative esterase PD40 PF07676.7 KOS16937.1 - 0.0046 16.5 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat AXE1 PF05448.7 KOS16937.1 - 0.013 14.0 0.0 1.4 7.2 0.0 2.2 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Bromo_TP PF07524.8 KOS16938.1 - 9.8e-09 34.8 0.0 1.7e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 KOS16938.1 - 0.051 13.3 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit BSP_II PF05432.6 KOS16938.1 - 0.13 11.5 18.9 0.017 14.4 5.5 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Pox_Ag35 PF03286.9 KOS16938.1 - 0.9 9.0 6.4 0.18 11.2 0.8 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Spore_coat_CotO PF14153.1 KOS16938.1 - 2.4 7.5 8.5 4 6.8 5.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF2457 PF10446.4 KOS16938.1 - 7.9 5.0 23.8 2.4 6.7 8.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Myc_N PF01056.13 KOS16938.1 - 9.7 5.2 12.8 0.14 11.3 3.9 1.6 2 0 0 2 2 2 0 Myc amino-terminal region Cnd3 PF12719.2 KOS16939.1 - 8.7e-89 297.4 1.0 2.7e-88 295.8 0.4 2.1 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KOS16939.1 - 1.7e-07 31.3 9.8 5e-05 23.4 1.2 6.2 5 2 2 7 7 7 3 HEAT repeats HEAT PF02985.17 KOS16939.1 - 5.8e-05 22.8 6.4 0.3 11.2 0.0 6.5 6 0 0 6 6 6 1 HEAT repeat RRM_1 PF00076.17 KOS16940.1 - 6.1e-57 189.1 0.1 1.3e-17 63.1 0.0 5.4 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16940.1 - 2.1e-43 146.1 0.1 1.4e-14 53.8 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16940.1 - 7.9e-21 73.6 0.6 7.5e-07 28.9 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-T PF15511.1 KOS16940.1 - 0.0042 16.3 12.2 0.0042 16.3 8.5 3.2 2 1 1 3 3 3 1 Centromere kinetochore component CENP-T Alg6_Alg8 PF03155.10 KOS16941.1 - 7.2e-141 470.2 23.5 9.6e-141 469.8 16.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.8 KOS16942.1 - 5.6e-24 84.5 0.1 2.2e-23 82.5 0.0 1.9 2 0 0 2 2 2 1 Legume-like lectin family Pox_Ag35 PF03286.9 KOS16942.1 - 0.0026 17.3 3.8 0.0037 16.8 2.6 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein DUF1319 PF07028.6 KOS16942.1 - 0.0054 16.9 0.4 0.01 16.0 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1319) Rrn6 PF10214.4 KOS16942.1 - 0.0077 14.3 6.4 0.01 14.0 4.4 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Macoilin PF09726.4 KOS16942.1 - 0.013 13.8 10.0 0.017 13.4 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein FUSC PF04632.7 KOS16942.1 - 0.023 13.1 2.6 0.031 12.7 1.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GOLD_2 PF13897.1 KOS16942.1 - 0.15 12.2 1.4 0.28 11.4 1.0 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Menin PF05053.8 KOS16942.1 - 0.92 7.5 5.9 1.2 7.1 4.1 1.1 1 0 0 1 1 1 0 Menin Striatin PF08232.7 KOS16942.1 - 1.7 8.9 9.3 17 5.6 0.0 2.3 2 0 0 2 2 2 0 Striatin family Hid1 PF12722.2 KOS16942.1 - 9 3.8 13.4 13 3.3 9.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SSrecog PF03531.9 KOS16943.1 - 1.3e-72 243.7 0.2 1.1e-71 240.7 0.1 2.2 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KOS16943.1 - 9.8e-24 83.1 0.0 2.6e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like TFIIA PF03153.8 KOS16943.1 - 3.2 7.5 24.0 2 8.2 15.3 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WAC_Acf1_DNA_bd PF10537.4 KOS16944.1 - 1.1e-35 121.8 0.1 7.3e-35 119.2 0.0 2.5 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KOS16944.1 - 9.6e-16 57.3 1.2 1.6e-15 56.5 0.8 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 KOS16944.1 - 3e-14 52.2 0.4 6.6e-14 51.1 0.3 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 KOS16944.1 - 0.00047 19.9 1.5 0.0015 18.3 0.0 2.6 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 KOS16944.1 - 0.00059 19.5 0.0 0.012 15.4 0.5 2.7 2 1 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 3 RPN7 PF10602.4 KOS16945.1 - 2.4e-51 173.5 0.4 4.5e-51 172.7 0.3 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KOS16945.1 - 1.5e-13 50.9 0.0 6.4e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 KOS16945.1 - 0.00087 19.0 0.6 2.5 8.2 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.13 KOS16945.1 - 0.11 12.4 1.6 4 7.3 0.0 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 KOS16945.1 - 0.11 12.1 0.7 4 7.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Prp18 PF02840.10 KOS16946.1 - 2e-51 173.6 0.0 2e-51 173.6 0.0 1.8 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 KOS16946.1 - 5.8e-12 44.6 0.4 5.8e-12 44.6 0.3 3.4 3 1 1 4 4 4 1 pre-mRNA processing factor 4 (PRP4) like CDC27 PF09507.5 KOS16946.1 - 0.064 12.4 14.4 0.098 11.8 10.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 U79_P34 PF03064.11 KOS16946.1 - 3.7 7.0 12.9 8 5.8 9.0 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Peptidase_M24 PF00557.19 KOS16947.1 - 1.3e-58 197.9 0.2 2.1e-58 197.3 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KOS16947.1 - 1.1e-20 73.3 0.0 2.3e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Fungal_trans PF04082.13 KOS16948.1 - 8e-26 90.4 0.4 8e-26 90.4 0.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS16948.1 - 6.1e-11 42.0 13.6 1.3e-10 40.9 9.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAP18 PF06487.7 KOS16949.1 - 1.8e-32 111.6 0.0 2.4e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Glyco_hydro_16 PF00722.16 KOS16951.1 - 2.1e-40 137.9 5.4 3.5e-40 137.2 3.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PT PF04886.7 KOS16952.1 - 0.00011 21.4 1.4 0.0003 20.0 0.9 1.7 1 0 0 1 1 1 1 PT repeat NUDIX PF00293.23 KOS16953.1 - 1.7e-19 69.8 0.0 2.7e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ribosomal_S14 PF00253.16 KOS16954.1 - 1.5e-08 33.9 0.6 1.2e-07 31.0 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e NUDIX PF00293.23 KOS16956.1 - 3.6e-06 26.6 0.5 5.6e-06 26.0 0.4 1.5 1 0 0 1 1 1 1 NUDIX domain Citrate_synt PF00285.16 KOS16957.1 - 1.4e-101 339.7 0.0 1.7e-101 339.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase adh_short PF00106.20 KOS16959.1 - 4.8e-27 94.9 2.7 6.7e-27 94.4 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS16959.1 - 1.2e-16 61.2 0.0 1.4e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS16959.1 - 2.2e-10 40.4 0.9 3.2e-10 39.9 0.6 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KOS16959.1 - 4.2e-06 26.5 0.2 7.8e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 KOS16959.1 - 0.00092 18.7 0.1 0.0015 17.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KOS16959.1 - 0.0034 16.4 0.1 0.0047 15.9 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KOS16959.1 - 0.012 15.6 0.7 0.027 14.4 0.5 1.5 1 1 0 1 1 1 0 NADH(P)-binding Methyltransf_18 PF12847.2 KOS16959.1 - 0.033 14.7 0.0 0.15 12.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KOS16959.1 - 0.048 14.1 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 KOS16959.1 - 0.052 12.4 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KOS16959.1 - 0.22 11.3 1.3 0.58 9.9 0.5 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ICL PF00463.16 KOS16960.1 - 9.6e-200 664.2 0.1 1.1e-199 664.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family DUF3818 PF12825.2 KOS16961.1 - 7e-24 84.1 0.0 1.9e-16 59.6 0.0 3.1 2 1 1 3 3 3 3 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KOS16961.1 - 7.2e-24 83.9 0.0 9.3e-23 80.3 0.0 2.3 1 1 0 1 1 1 1 PX-associated POX PF07526.6 KOS16961.1 - 0.28 11.3 1.7 0.64 10.2 0.0 2.1 2 0 0 2 2 2 0 Associated with HOX DUF4449 PF14613.1 KOS16962.1 - 7e-60 201.6 2.8 7e-60 201.6 1.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) DUF3722 PF12519.3 KOS16963.1 - 6.1e-77 258.3 0.0 9.2e-77 257.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 KOS16963.1 - 0.00011 21.5 0.1 0.004 16.4 0.0 2.8 4 0 0 4 4 4 1 Eukaryotic porin Plant_tran PF04827.9 KOS16963.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Plant transposon protein Zip PF02535.17 KOS16964.1 - 7.9e-55 186.0 2.4 3.9e-54 183.7 1.6 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Herpes_teg_N PF04843.7 KOS16964.1 - 0.17 11.3 0.1 0.8 9.1 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region Ribosomal_S19e PF01090.14 KOS16965.1 - 6.6e-57 190.8 0.2 7.5e-57 190.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e SCP1201-deam PF14428.1 KOS16966.1 - 0.054 13.1 0.3 1.4 8.5 0.2 2.5 1 1 0 1 1 1 0 SCP1.201-like deaminase DEAD PF00270.24 KOS16967.1 - 1.7e-20 73.1 0.1 9.1e-20 70.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS16967.1 - 3.4e-17 62.0 0.1 1.5e-15 56.7 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RQC PF09382.5 KOS16967.1 - 4.1e-13 48.9 0.8 2.6e-11 43.1 0.0 2.4 2 0 0 2 2 2 1 RQC domain ResIII PF04851.10 KOS16967.1 - 0.0011 18.7 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRDC PF00570.18 KOS16967.1 - 0.0019 17.8 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 HRDC domain SNF2_N PF00176.18 KOS16967.1 - 0.016 14.0 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain SPT6_acidic PF14632.1 KOS16967.1 - 0.28 11.3 12.1 0.021 14.9 4.5 2.0 2 0 0 2 2 2 0 Acidic N-terminal SPT6 KAR9 PF08580.5 KOS16968.1 - 3.5e-120 402.3 0.0 3.5e-120 402.3 0.0 3.4 3 2 0 3 3 3 1 Yeast cortical protein KAR9 SusD PF07980.6 KOS16968.1 - 0.13 11.7 0.2 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 SusD family Tim17 PF02466.14 KOS16969.1 - 2e-20 73.1 0.0 2.9e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family IF3_C PF00707.17 KOS16971.1 - 1.2e-08 34.5 0.0 1.7e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 KOS16971.1 - 0.029 13.7 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor ARS2 PF04959.8 KOS16971.1 - 0.72 10.0 7.7 0.68 10.0 0.9 2.2 2 0 0 2 2 2 0 Arsenite-resistance protein 2 AMP-binding PF00501.23 KOS16972.1 - 4.9e-52 176.7 0.0 6.9e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS16972.1 - 2.1e-09 38.2 0.8 4.9e-09 37.0 0.2 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DEAD PF00270.24 KOS16973.1 - 1.1e-40 138.8 0.3 3e-40 137.4 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS16973.1 - 4e-29 100.2 0.2 8.5e-29 99.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 KOS16973.1 - 0.0035 16.6 0.5 0.0062 15.8 0.1 1.5 2 0 0 2 2 2 1 SecA DEAD-like domain ResIII PF04851.10 KOS16973.1 - 0.012 15.4 0.1 0.049 13.4 0.1 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KOS16973.1 - 0.012 15.1 0.5 0.029 13.9 0.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KOS16973.1 - 0.015 15.0 0.2 0.038 13.7 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 KOS16973.1 - 0.043 13.5 0.4 0.14 11.8 0.0 2.1 3 1 0 3 3 3 0 Flavivirus DEAD domain AAA_22 PF13401.1 KOS16973.1 - 0.062 13.4 0.8 0.3 11.2 0.6 2.0 1 1 0 1 1 1 0 AAA domain Ribosomal_L34 PF00468.12 KOS16974.1 - 2e-11 43.3 11.0 4.4e-11 42.2 7.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L34 LRR_6 PF13516.1 KOS16975.1 - 0.0014 18.4 0.3 0.75 10.0 0.0 4.8 5 0 0 5 5 5 1 Leucine Rich repeat IGR PF09597.5 KOS16975.1 - 0.043 13.7 0.0 7.1 6.6 0.0 3.1 4 0 0 4 4 4 0 IGR protein motif NinF PF05810.7 KOS16975.1 - 0.77 9.6 6.7 0.9 9.3 0.0 3.1 3 1 1 4 4 4 0 NinF protein Ribosomal_60s PF00428.14 KOS16975.1 - 1 9.8 7.3 5.2 7.5 5.0 2.2 1 1 0 1 1 1 0 60s Acidic ribosomal protein Lipase_3 PF01764.20 KOS16976.1 - 5.9e-33 113.4 0.0 8.6e-33 112.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 KOS16976.1 - 0.0026 17.5 0.3 0.006 16.3 0.2 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_5 PF12695.2 KOS16976.1 - 0.0064 16.2 0.0 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS16976.1 - 0.0098 15.7 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KOS16976.1 - 0.011 15.4 0.3 0.026 14.2 0.2 1.8 1 1 0 1 1 1 0 Cutinase dsrm PF00035.20 KOS16977.1 - 0.016 15.7 0.6 0.1 13.1 0.1 2.5 2 1 0 2 2 2 0 Double-stranded RNA binding motif DUF1682 PF07946.9 KOS16978.1 - 4.6e-96 321.4 0.0 5.3e-96 321.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF2910 PF11139.3 KOS16979.1 - 0.0059 15.7 0.1 0.0059 15.7 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2910) DUF484 PF04340.7 KOS16979.1 - 0.065 12.6 0.1 0.098 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF484 SMC_N PF02463.14 KOS16980.1 - 3.7e-67 225.7 0.0 5.8e-67 225.1 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KOS16980.1 - 2e-28 98.7 0.1 1.8e-27 95.7 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KOS16980.1 - 9.4e-18 65.1 0.1 1.2e-08 35.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 KOS16980.1 - 1.5e-10 40.6 20.6 4.7e-05 22.6 9.6 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KOS16980.1 - 1.6e-09 38.4 36.2 1.6e-09 38.4 25.1 7.1 2 2 1 3 3 2 1 AAA domain AAA_27 PF13514.1 KOS16980.1 - 4.9e-05 21.2 102.0 0.00024 18.9 29.8 3.1 2 1 1 3 3 3 2 AAA domain SbcCD_C PF13558.1 KOS16980.1 - 0.00021 21.1 0.0 0.00095 19.0 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KOS16980.1 - 0.00027 20.3 0.0 0.0007 19.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 KOS16980.1 - 0.0026 16.9 4.5 0.0026 16.9 3.1 7.3 4 3 2 7 7 7 1 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 KOS16980.1 - 0.026 14.2 0.7 0.026 14.2 0.5 6.9 4 2 3 8 8 8 0 Laminin Domain II Reo_sigmaC PF04582.7 KOS16980.1 - 0.034 13.3 20.6 0.67 9.0 0.4 4.8 5 0 0 5 5 5 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KOS16980.1 - 0.12 10.8 0.0 0.12 10.8 0.0 6.1 3 2 3 6 6 5 0 AAA domain ABC_tran PF00005.22 KOS16980.1 - 0.29 11.4 0.0 0.29 11.4 0.0 6.2 3 2 0 3 3 1 0 ABC transporter Pinin_SDK_memA PF04696.8 KOS16981.1 - 8.2e-24 83.6 12.0 8.2e-24 83.6 8.4 1.7 1 1 0 1 1 1 1 pinin/SDK/memA/ protein conserved region DUF566 PF04484.7 KOS16981.1 - 0.44 10.0 9.1 0.69 9.3 6.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) PHF5 PF03660.9 KOS16982.1 - 3.4e-51 171.7 11.1 3.9e-51 171.6 7.7 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 KOS16982.1 - 0.53 10.1 15.2 7.4 6.4 1.6 2.8 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 KOS16982.1 - 0.81 9.4 15.6 1.8 8.3 0.5 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.24 KOS16982.1 - 8.6 6.1 15.7 0.3 10.8 4.8 2.5 1 1 1 2 2 2 0 PHD-finger PolC_DP2 PF03833.8 KOS16982.1 - 9.9 3.6 7.4 9.4 3.7 5.1 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PA14_2 PF10528.4 KOS16983.1 - 3.2e-17 62.5 0.4 6.1e-17 61.6 0.3 1.5 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.7 KOS16983.1 - 5.3e-05 22.8 0.2 8.8e-05 22.1 0.2 1.5 1 1 0 1 1 1 1 PA14 domain Glycos_transf_1 PF00534.15 KOS16984.1 - 1.1e-22 80.3 0.0 1.8e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KOS16984.1 - 3.5e-09 36.9 0.0 8.8e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KOS16984.1 - 0.0028 17.8 0.0 0.0055 16.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 UvdE PF03851.9 KOS16985.1 - 3.2e-108 360.9 0.0 5.3e-108 360.2 0.0 1.3 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF4037 PF13228.1 KOS16985.1 - 0.14 12.3 0.0 0.44 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) Fungal_trans PF04082.13 KOS16986.1 - 1.1e-11 44.1 0.0 2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1546 PF07571.8 KOS16987.1 - 8.7e-27 93.0 0.7 3e-26 91.3 0.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 KOS16987.1 - 1.3e-20 73.1 0.2 2.2e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 KOS16987.1 - 0.00012 22.1 0.1 0.00021 21.3 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PXA PF02194.10 KOS16987.1 - 0.071 12.6 0.6 0.13 11.7 0.4 1.5 1 0 0 1 1 1 0 PXA domain Pex14_N PF04695.8 KOS16987.1 - 0.54 10.3 9.9 0.034 14.2 3.3 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4557 PF15101.1 KOS16987.1 - 0.61 9.8 5.5 1.1 9.1 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Pex16 PF08610.5 KOS16987.1 - 0.9 8.4 3.9 1.6 7.6 2.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) ADH_N PF08240.7 KOS16988.1 - 7.6e-26 90.0 4.8 1.3e-25 89.2 3.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KOS16988.1 - 1.1e-21 76.7 0.0 3.5e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KOS16988.1 - 2.4e-07 31.6 0.0 4.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KOS16988.1 - 0.0003 19.9 0.0 0.00054 19.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KOS16988.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_8 PF13450.1 KOS16989.1 - 4.5e-09 36.2 0.1 9.2e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KOS16989.1 - 1.2e-08 34.4 0.0 3.2e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 KOS16989.1 - 4.3e-07 29.1 0.2 1.4e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KOS16989.1 - 8.3e-07 28.4 0.0 3.8e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KOS16989.1 - 3.2e-06 27.4 0.8 6.4e-06 26.4 0.1 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KOS16989.1 - 6.3e-06 25.2 0.0 8.6e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KOS16989.1 - 7e-06 26.2 0.0 0.00063 19.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KOS16989.1 - 2.2e-05 23.7 0.0 3.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KOS16989.1 - 4.7e-05 22.0 0.0 6.8e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KOS16989.1 - 0.00024 21.0 0.1 0.0005 20.0 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KOS16989.1 - 0.0048 16.3 0.1 0.0091 15.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KOS16989.1 - 0.0099 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 KOS16989.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.14 KOS16989.1 - 0.011 14.7 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain PNRC PF15365.1 KOS16989.1 - 0.03 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator Trp_halogenase PF04820.9 KOS16989.1 - 0.055 12.0 0.0 0.076 11.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.7 KOS16989.1 - 0.088 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein YjeF_N PF03853.10 KOS16989.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_10 PF13460.1 KOS16989.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 KOS16989.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sdh_cyt PF01127.17 KOS16990.1 - 2.4e-17 62.8 2.7 3.1e-17 62.5 1.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SET PF00856.23 KOS16992.1 - 5.8e-16 59.2 0.0 1.2e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 KOS16992.1 - 8.7e-06 25.6 0.1 1.9e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding PGM_PMM_II PF02879.11 KOS16992.1 - 0.085 13.1 0.1 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Opi1 PF08618.5 KOS16993.1 - 2.2e-77 260.7 0.0 9.2e-48 163.2 0.3 3.2 1 1 1 3 3 3 3 Transcription factor Opi1 DUF2359 PF10151.4 KOS16993.1 - 0.0095 14.5 0.5 0.015 13.8 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2359) Perilipin PF03036.11 KOS16993.1 - 0.027 13.3 0.4 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Perilipin family Adap_comp_sub PF00928.16 KOS16994.1 - 8.3e-91 303.7 0.0 1.1e-90 303.3 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KOS16994.1 - 3.6e-09 36.4 0.2 6e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KOS16994.1 - 0.054 12.6 0.0 0.24 10.5 0.0 1.8 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain TIP120 PF08623.5 KOS16995.1 - 1.6e-63 213.3 3.9 1.3e-60 203.8 0.0 4.6 3 1 2 5 5 5 2 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 KOS16995.1 - 1.3e-17 63.7 27.3 0.0064 16.7 0.1 10.3 8 2 3 12 12 12 7 HEAT repeats HEAT PF02985.17 KOS16995.1 - 5.9e-14 50.8 19.8 0.3 11.2 0.1 10.6 11 0 0 11 11 11 5 HEAT repeat HEAT_EZ PF13513.1 KOS16995.1 - 2.6e-07 30.9 29.5 0.86 10.1 0.0 11.5 10 2 3 13 13 13 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KOS16995.1 - 7e-05 23.1 0.2 5.7 7.4 0.0 6.4 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KOS16995.1 - 0.0019 18.0 10.8 2.2 8.0 0.1 5.5 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.2 KOS16995.1 - 0.0022 17.0 0.0 6 5.7 0.0 4.1 4 0 0 4 4 4 2 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.15 KOS16995.1 - 0.0044 15.4 18.5 0.019 13.2 0.1 6.6 5 2 1 7 7 7 1 Adaptin N terminal region RasGEF_N_2 PF14663.1 KOS16995.1 - 0.032 14.1 0.1 1.4 8.8 0.0 3.6 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Proteasom_PSMB PF10508.4 KOS16995.1 - 0.033 12.4 2.6 1.3 7.2 0.1 3.4 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit MMS19_C PF12460.3 KOS16995.1 - 0.084 11.5 8.3 1 8.0 0.6 4.1 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal ParcG PF10274.4 KOS16995.1 - 5.7 6.7 8.1 71 3.2 0.0 4.8 6 0 0 6 6 6 0 Parkin co-regulated protein Cpn60_TCP1 PF00118.19 KOS16996.1 - 4.1e-139 464.3 4.0 4.7e-139 464.1 2.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HAD PF12710.2 KOS16996.1 - 0.02 15.0 0.0 0.15 12.2 0.0 2.0 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS16996.1 - 0.19 12.1 5.2 0.067 13.5 0.4 2.6 2 2 0 2 2 2 0 haloacid dehalogenase-like hydrolase HMG_box PF00505.14 KOS16997.1 - 2.7e-05 24.3 1.2 8.5e-05 22.7 0.9 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box Glyco_hydro_2 PF00703.16 KOS16997.1 - 3.4 8.1 10.9 0.83 10.1 0.8 2.7 1 1 1 2 2 2 0 Glycosyl hydrolases family 2 DUF155 PF02582.9 KOS16998.1 - 8.3e-56 188.6 0.4 1.2e-55 188.1 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Ribosomal_L37ae PF01780.14 KOS16999.1 - 9.3e-39 131.1 10.0 1e-38 131.0 7.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 KOS16999.1 - 0.0029 17.3 3.5 0.0046 16.7 2.5 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 KOS16999.1 - 0.0031 16.9 2.6 0.057 12.8 0.1 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain zf-H2C2_2 PF13465.1 KOS16999.1 - 0.0066 16.6 1.3 0.085 13.1 0.3 2.2 2 0 0 2 2 2 1 Zinc-finger double domain DUF1364 PF07102.7 KOS16999.1 - 0.051 13.4 0.9 0.071 12.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) OrfB_Zn_ribbon PF07282.6 KOS16999.1 - 0.058 13.0 1.4 0.08 12.6 1.0 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain C1_2 PF03107.11 KOS16999.1 - 0.059 13.4 3.3 0.13 12.3 0.2 2.2 2 0 0 2 2 2 0 C1 domain C1_1 PF00130.17 KOS16999.1 - 0.08 12.6 2.4 0.12 12.1 1.7 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NCD3G PF07562.9 KOS16999.1 - 0.15 11.7 1.5 0.21 11.3 1.0 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR Zn-ribbon_8 PF09723.5 KOS16999.1 - 0.17 11.8 1.6 0.64 10.0 0.2 2.1 2 0 0 2 2 2 0 Zinc ribbon domain Sgf11 PF08209.6 KOS16999.1 - 0.17 11.2 1.3 1 8.7 0.1 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-BED PF02892.10 KOS16999.1 - 0.22 11.2 5.1 2 8.2 0.5 2.3 1 1 1 2 2 2 0 BED zinc finger Elf1 PF05129.8 KOS16999.1 - 0.23 11.1 3.6 0.36 10.5 2.5 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like CarbpepA_inh PF02977.10 KOS16999.1 - 0.39 10.3 3.7 0.43 10.2 0.2 2.2 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor zf-C2H2 PF00096.21 KOS16999.1 - 1.2 9.6 3.5 1.2 9.6 0.6 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type FAD_binding_2 PF00890.19 KOS17000.1 - 3.4e-125 418.1 4.1 4.2e-125 417.8 2.8 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KOS17000.1 - 6e-46 155.4 0.3 8.8e-46 154.9 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 KOS17000.1 - 3.4e-06 27.0 0.1 0.005 16.7 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KOS17000.1 - 1.4e-05 24.3 0.3 0.024 13.7 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KOS17000.1 - 0.00013 21.0 1.0 0.038 12.8 1.3 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 KOS17000.1 - 0.001 18.0 0.7 0.0046 15.8 0.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KOS17000.1 - 0.0018 17.3 0.1 0.0039 16.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KOS17000.1 - 0.27 9.6 1.2 0.74 8.2 0.3 2.0 3 0 0 3 3 3 0 HI0933-like protein TPR_11 PF13414.1 KOS17001.1 - 0.0011 18.5 0.2 0.0028 17.2 0.2 1.7 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 KOS17001.1 - 0.013 16.1 3.3 0.013 16.1 2.3 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KOS17001.1 - 0.024 14.5 1.0 0.18 11.8 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KOS17001.1 - 0.22 11.9 7.3 0.93 9.8 2.0 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat U3_snoRNA_assoc PF08297.6 KOS17002.1 - 0.011 15.9 22.8 0.24 11.6 14.6 2.8 2 1 0 2 2 2 0 U3 snoRNA associated CDC27 PF09507.5 KOS17002.1 - 0.41 9.8 25.3 0.53 9.4 17.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2413 PF10310.4 KOS17002.1 - 1.8 7.2 19.1 3.1 6.5 13.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) FLO_LFY PF01698.11 KOS17002.1 - 2.8 6.6 14.5 4.4 6.0 10.0 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein PLRV_ORF5 PF01690.12 KOS17002.1 - 4 6.4 14.0 4.7 6.2 9.7 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PH_10 PF15411.1 KOS17003.1 - 1.3e-25 89.8 0.8 2e-25 89.2 0.6 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 KOS17003.1 - 6.4e-11 42.1 0.0 1.4e-10 41.0 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KOS17003.1 - 4e-09 36.4 0.0 6.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain PH PF00169.24 KOS17003.1 - 0.016 15.3 0.3 0.036 14.2 0.2 1.6 1 0 0 1 1 1 0 PH domain DUF1147 PF06615.6 KOS17003.1 - 0.053 13.3 0.5 0.16 11.8 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) PHD PF00628.24 KOS17004.1 - 2.3e-08 33.5 3.8 4.1e-08 32.7 2.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KOS17004.1 - 1.5e-05 24.2 2.6 2.3e-05 23.6 1.8 1.3 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 KOS17004.1 - 0.08 12.2 0.2 0.2 10.9 0.1 1.7 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 KOS17004.1 - 0.089 12.5 1.2 0.18 11.5 0.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF282 PF03380.9 KOS17004.1 - 1.2 8.9 3.8 1.9 8.3 2.6 1.3 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 MRP-L46 PF11788.3 KOS17005.1 - 3.7e-10 40.4 0.0 5.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KOS17005.1 - 8e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain TAFII28 PF04719.9 KOS17006.1 - 1.1e-14 54.0 1.9 2.4e-13 49.6 0.1 2.7 2 1 0 2 2 2 1 hTAFII28-like protein conserved region RR_TM4-6 PF06459.7 KOS17006.1 - 5.2 6.8 15.2 7.6 6.3 8.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Glyco_hydro_18 PF00704.23 KOS17008.1 - 1.4e-18 67.4 5.3 1.4e-18 67.4 3.7 2.5 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 KOS17008.1 - 2e-10 40.1 14.5 7.4e-10 38.3 10.0 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Euplotes_phero PF05842.6 KOS17008.1 - 0.012 15.9 0.1 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Pyr_redox_2 PF07992.9 KOS17009.1 - 5.6e-17 62.2 0.0 7.7e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KOS17009.1 - 1.6e-06 27.2 0.1 1.4e-05 24.1 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.1 KOS17009.1 - 1.7e-06 27.8 0.3 0.0073 16.0 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KOS17009.1 - 3.4e-06 27.2 0.1 0.069 13.1 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KOS17009.1 - 1.3e-05 24.3 0.1 0.0024 16.8 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.1 KOS17009.1 - 1.6e-05 24.0 0.2 0.00026 20.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KOS17009.1 - 1.9e-05 23.7 1.4 0.00015 20.8 0.2 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KOS17009.1 - 3.6e-05 23.6 0.1 0.00042 20.2 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KOS17009.1 - 3.9e-05 22.3 0.3 0.00011 20.8 0.1 1.8 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.7 KOS17009.1 - 0.001 18.1 0.1 0.0038 16.1 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KOS17009.1 - 0.0076 15.3 0.1 0.014 14.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KOS17009.1 - 0.0076 15.3 0.1 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KOS17009.1 - 0.026 13.6 0.7 0.039 13.0 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KOS17009.1 - 0.14 12.6 0.1 0.39 11.1 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KOS17009.1 - 0.15 10.6 0.0 0.25 9.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DUF1680 PF07944.7 KOS17010.1 - 9.4e-21 73.6 0.0 4e-19 68.2 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Methyltransf_31 PF13847.1 KOS17011.1 - 1.2e-21 76.9 0.0 3.1e-21 75.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain EcKinase PF02958.15 KOS17011.1 - 2.4e-17 63.0 0.0 1.1e-16 60.8 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase Methyltransf_18 PF12847.2 KOS17011.1 - 2.4e-15 57.0 0.0 6.7e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS17011.1 - 4.4e-14 52.7 0.0 2e-13 50.6 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS17011.1 - 2.1e-13 50.5 0.0 7.4e-13 48.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS17011.1 - 4.1e-13 49.6 0.0 8.8e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS17011.1 - 1.7e-11 44.1 0.1 1.1e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain APH PF01636.18 KOS17011.1 - 5.6e-11 42.6 2.0 5.6e-11 42.6 1.4 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Methyltransf_23 PF13489.1 KOS17011.1 - 3.4e-09 36.6 0.0 8.1e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS17011.1 - 2.1e-07 30.4 0.0 4.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KOS17011.1 - 2e-06 26.9 0.0 4.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 KOS17011.1 - 2.8e-06 26.6 0.0 5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 KOS17011.1 - 0.00065 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 KOS17011.1 - 0.00089 18.5 0.0 0.0021 17.3 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase FmrO PF07091.6 KOS17011.1 - 0.0035 16.3 0.0 0.0059 15.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) DUF938 PF06080.7 KOS17011.1 - 0.013 15.0 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.8 KOS17011.1 - 0.021 13.9 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 KOS17011.1 - 0.057 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase GCD14 PF08704.5 KOS17011.1 - 0.057 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_32 PF13679.1 KOS17011.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 KOS17011.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PSDC PF12588.3 KOS17012.1 - 3.3e-50 169.3 0.0 4.7e-50 168.8 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 KOS17012.1 - 3e-31 108.3 0.0 4.2e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 KOS17012.1 - 0.00047 19.7 0.6 0.11 12.2 0.2 2.4 2 0 0 2 2 2 2 Biotin-lipoyl like Formyl_trans_N PF00551.14 KOS17013.1 - 5.1e-35 120.6 0.1 6.9e-35 120.2 0.1 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 KOS17013.1 - 7.5e-09 34.9 0.0 7.5e-09 34.9 0.0 2.7 3 1 0 3 3 3 1 ACT domain ACT_6 PF13740.1 KOS17013.1 - 0.00065 19.3 0.0 0.0033 17.0 0.0 2.2 2 1 1 3 3 3 1 ACT domain CbiQ PF02361.11 KOS17013.1 - 1.1 8.7 7.0 1.8 8.0 4.9 1.4 1 0 0 1 1 1 0 Cobalt transport protein Thymidylate_kin PF02223.12 KOS17014.1 - 1.4e-40 138.6 0.0 2.4e-40 137.8 0.0 1.4 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 KOS17014.1 - 0.00033 20.6 0.0 0.00054 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 KOS17014.1 - 0.02 14.5 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 KOS17014.1 - 0.025 13.7 0.0 0.05 12.8 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Glyco_hyd_65N_2 PF14498.1 KOS17015.1 - 2.2e-46 158.4 0.0 3.3e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain SRP54 PF00448.17 KOS17016.1 - 2.2e-77 258.9 2.1 2.4e-77 258.8 0.5 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KOS17016.1 - 8.1e-26 90.3 5.7 8.1e-26 90.3 4.0 4.2 3 2 2 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.14 KOS17016.1 - 3.6e-16 59.0 0.3 8.6e-16 57.8 0.2 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KOS17016.1 - 2.4e-09 36.8 0.2 8.5e-09 35.1 0.1 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KOS17016.1 - 2.2e-08 34.0 0.1 7e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KOS17016.1 - 6e-06 26.0 0.0 2e-05 24.3 0.0 1.9 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 KOS17016.1 - 1.3e-05 24.7 0.1 5.4e-05 22.6 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 KOS17016.1 - 1.8e-05 25.5 0.0 4.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 KOS17016.1 - 0.00056 18.7 3.2 0.00079 18.2 0.5 2.4 2 1 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 KOS17016.1 - 0.00086 19.4 0.0 0.0033 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 KOS17016.1 - 0.00098 18.8 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_31 PF13614.1 KOS17016.1 - 0.0011 18.9 0.2 1.1 9.1 0.0 2.7 2 1 1 3 3 2 2 AAA domain Zeta_toxin PF06414.7 KOS17016.1 - 0.0014 17.8 0.0 0.0028 16.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 KOS17016.1 - 0.0015 18.5 0.3 0.0044 17.0 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain Thymidylate_kin PF02223.12 KOS17016.1 - 0.0016 17.8 0.3 0.01 15.2 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase SRPRB PF09439.5 KOS17016.1 - 0.0023 17.1 0.7 2.7 7.1 0.1 3.2 2 1 0 3 3 3 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 KOS17016.1 - 0.0067 15.9 0.2 0.045 13.2 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 KOS17016.1 - 0.0089 16.3 0.0 0.023 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KOS17016.1 - 0.012 15.5 0.1 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KOS17016.1 - 0.015 15.2 0.0 0.17 11.8 0.0 2.4 1 1 0 2 2 2 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.4 KOS17016.1 - 0.015 13.9 0.0 0.032 12.8 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PTPlike_phytase PF14566.1 KOS17016.1 - 0.023 14.7 0.1 2.4 8.1 0.0 3.4 4 0 0 4 4 4 0 Inositol hexakisphosphate 6PF2K PF01591.13 KOS17016.1 - 0.032 13.2 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_19 PF13245.1 KOS17016.1 - 0.035 13.8 0.1 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 KOS17016.1 - 0.055 12.8 0.1 0.25 10.7 0.1 2.2 1 1 0 1 1 1 0 AAA-like domain Glyco_transf_4 PF13439.1 KOS17016.1 - 0.056 13.1 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 VirE PF05272.6 KOS17016.1 - 0.064 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E NTPase_1 PF03266.10 KOS17016.1 - 0.068 12.8 0.9 2 8.1 0.0 2.4 1 1 0 2 2 2 0 NTPase Arf PF00025.16 KOS17016.1 - 0.081 12.1 0.1 0.27 10.4 0.0 1.9 2 0 0 2 2 1 0 ADP-ribosylation factor family AAA PF00004.24 KOS17016.1 - 0.087 13.0 0.9 0.35 11.0 0.2 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KOS17016.1 - 0.093 12.1 0.7 0.3 10.4 0.1 2.1 2 1 0 2 2 1 0 AAA domain ResIII PF04851.10 KOS17016.1 - 0.12 12.2 0.3 2 8.1 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Glyco_trans_4_4 PF13579.1 KOS17016.1 - 0.13 12.4 0.3 0.26 11.4 0.0 1.6 2 0 0 2 2 1 0 Glycosyl transferase 4-like domain PLAC8 PF04749.12 KOS17017.1 - 0.0014 19.1 1.9 0.002 18.6 1.3 1.3 1 0 0 1 1 1 1 PLAC8 family MIP-T3 PF10243.4 KOS17018.1 - 5.4 5.3 43.6 6.8 5.0 30.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Tektin PF03148.9 KOS17019.1 - 0.00011 20.9 7.7 0.0011 17.6 0.0 2.6 2 1 1 3 3 3 2 Tektin family Myosin_tail_1 PF01576.14 KOS17019.1 - 0.00012 19.9 6.9 0.00017 19.4 4.8 1.3 1 0 0 1 1 1 1 Myosin tail bZIP_2 PF07716.10 KOS17019.1 - 0.00015 21.5 5.4 0.59 9.9 0.2 4.1 4 0 0 4 4 3 1 Basic region leucine zipper CCDC155 PF14662.1 KOS17019.1 - 0.00036 20.1 6.6 0.00088 18.9 4.6 1.6 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 CENP-F_leu_zip PF10473.4 KOS17019.1 - 0.00047 20.0 4.3 0.00047 20.0 3.0 2.7 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 KOS17019.1 - 0.00049 19.9 1.0 0.6 10.1 0.0 3.7 1 1 2 3 3 3 1 bZIP transcription factor Reo_sigmaC PF04582.7 KOS17019.1 - 0.0005 19.3 1.3 0.00081 18.6 0.9 1.4 1 0 0 1 1 1 1 Reovirus sigma C capsid protein PspA_IM30 PF04012.7 KOS17019.1 - 0.00077 18.8 1.4 0.00077 18.8 0.9 3.3 1 1 1 3 3 3 1 PspA/IM30 family IncA PF04156.9 KOS17019.1 - 0.002 17.7 2.7 0.0038 16.8 1.9 1.5 1 0 0 1 1 1 1 IncA protein DUF1664 PF07889.7 KOS17019.1 - 0.0025 17.5 5.1 1.7 8.4 0.0 3.6 2 1 2 4 4 3 2 Protein of unknown function (DUF1664) Filament PF00038.16 KOS17019.1 - 0.0089 15.5 6.6 0.22 10.9 1.9 2.4 1 1 1 2 2 2 2 Intermediate filament protein CENP-Q PF13094.1 KOS17019.1 - 0.025 14.6 6.7 0.074 13.0 0.6 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 KOS17019.1 - 0.025 13.5 3.3 0.045 12.7 2.3 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LXG PF04740.7 KOS17019.1 - 0.04 13.7 0.8 0.82 9.4 0.0 2.4 1 1 1 2 2 2 0 LXG domain of WXG superfamily TPR_MLP1_2 PF07926.7 KOS17019.1 - 0.049 13.3 3.1 0.21 11.3 1.4 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein MCC-bdg_PDZ PF10506.4 KOS17019.1 - 0.056 13.2 0.8 4.4 7.2 0.0 3.2 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF904 PF06005.7 KOS17019.1 - 0.062 13.6 3.5 2.7 8.3 0.1 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Macoilin PF09726.4 KOS17019.1 - 0.075 11.3 8.2 0.31 9.2 5.7 1.8 1 1 0 1 1 1 0 Transmembrane protein DUF1382 PF07131.6 KOS17019.1 - 0.079 13.0 0.4 25 5.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1382) Laminin_II PF06009.7 KOS17019.1 - 0.084 12.6 5.1 0.91 9.2 0.2 3.4 2 1 1 3 3 3 0 Laminin Domain II APG6 PF04111.7 KOS17019.1 - 0.088 11.8 1.3 0.14 11.2 0.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ATG16 PF08614.6 KOS17019.1 - 0.1 12.4 8.5 0.64 9.8 5.9 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 KOS17019.1 - 0.12 10.8 0.1 0.17 10.3 0.1 1.1 1 0 0 1 1 1 0 AAA domain CagA PF03507.8 KOS17019.1 - 0.12 12.2 1.6 0.38 10.5 0.6 2.2 1 1 1 2 2 2 0 CagA exotoxin Tropomyosin_1 PF12718.2 KOS17019.1 - 0.12 12.1 5.7 0.11 12.3 0.2 2.8 1 1 1 2 2 2 0 Tropomyosin like TBPIP PF07106.8 KOS17019.1 - 0.13 11.7 1.1 1.1 8.7 0.7 2.1 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Striatin PF08232.7 KOS17019.1 - 0.14 12.4 5.2 0.37 11.0 1.1 3.0 1 1 1 2 2 2 0 Striatin family ADIP PF11559.3 KOS17019.1 - 0.15 11.9 4.9 0.11 12.4 0.4 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 KOS17019.1 - 0.18 11.5 8.2 0.35 10.6 0.2 3.9 3 1 3 6 6 5 0 TATA element modulatory factor 1 DNA binding Bacillus_HBL PF05791.6 KOS17019.1 - 0.19 11.1 2.4 4.7 6.5 0.7 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) CALCOCO1 PF07888.6 KOS17019.1 - 0.21 9.8 7.6 0.42 8.8 5.3 1.5 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.6 KOS17019.1 - 0.25 9.9 2.5 0.25 9.9 0.4 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein ERM PF00769.14 KOS17019.1 - 0.25 10.8 7.3 0.77 9.2 0.2 2.4 1 1 2 3 3 3 0 Ezrin/radixin/moesin family DUF948 PF06103.6 KOS17019.1 - 0.39 10.6 3.2 8.2 6.3 0.0 3.6 3 1 2 5 5 3 0 Bacterial protein of unknown function (DUF948) DUF972 PF06156.8 KOS17019.1 - 0.58 10.5 3.3 10 6.4 0.2 3.2 2 1 1 3 3 2 0 Protein of unknown function (DUF972) HAUS-augmin3 PF14932.1 KOS17019.1 - 0.62 9.2 4.4 1.1 8.4 1.1 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Syntaxin PF00804.20 KOS17019.1 - 1.1 9.4 5.4 1.4 9.0 1.0 3.0 1 1 1 2 2 2 0 Syntaxin Ribosomal_L1 PF00687.16 KOS17020.1 - 3e-28 98.6 0.0 3.5e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family KH_2 PF07650.12 KOS17020.1 - 0.11 12.0 0.3 2.2 7.8 0.1 2.6 1 1 1 2 2 2 0 KH domain COG2 PF06148.6 KOS17021.1 - 4.5e-26 91.3 0.5 8.2e-26 90.4 0.4 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 KOS17021.1 - 0.00037 20.2 0.1 0.0025 17.6 0.1 2.4 2 1 0 2 2 2 1 Vps51/Vps67 DUF2450 PF10475.4 KOS17021.1 - 0.0017 17.3 0.1 0.017 14.0 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG5 PF10392.4 KOS17021.1 - 0.0022 17.9 0.1 0.0043 17.0 0.1 1.5 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Spc7 PF08317.6 KOS17021.1 - 0.0078 14.9 2.3 0.016 13.9 1.6 1.4 1 1 0 1 1 1 1 Spc7 kinetochore protein Dor1 PF04124.7 KOS17021.1 - 0.02 13.3 1.2 0.03 12.7 0.8 1.2 1 0 0 1 1 1 0 Dor1-like family TFIIA PF03153.8 KOS17021.1 - 0.022 14.6 3.8 0.033 14.0 2.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myosin_tail_1 PF01576.14 KOS17021.1 - 0.033 11.9 3.4 0.047 11.4 2.4 1.3 1 0 0 1 1 1 0 Myosin tail NPV_P10 PF05531.7 KOS17021.1 - 0.043 14.0 0.6 0.24 11.7 0.1 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Cortex-I_coil PF09304.5 KOS17021.1 - 0.08 12.9 4.5 0.088 12.8 1.0 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil WEMBL PF05701.6 KOS17021.1 - 0.18 10.2 3.6 0.31 9.4 2.5 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light IncA PF04156.9 KOS17021.1 - 0.98 8.9 4.3 0.84 9.2 1.8 1.7 2 0 0 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 KOS17021.1 - 1.1 8.9 3.7 2.7 7.7 0.5 2.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Nucleoplasmin PF03066.10 KOS17021.1 - 1.5 8.3 10.2 2.5 7.6 7.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 KOS17021.1 - 1.5 7.4 16.2 2.3 6.8 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 KOS17021.1 - 6.9 5.0 7.8 9 4.6 5.4 1.1 1 0 0 1 1 1 0 Daxx Family Hap4_Hap_bind PF10297.4 KOS17022.1 - 5.4e-09 35.5 7.1 5.4e-09 35.5 4.9 2.7 3 0 0 3 3 3 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 KOS17022.1 - 2.8e-05 23.9 11.5 2.8e-05 23.9 8.0 2.0 2 1 1 3 3 3 1 bZIP transcription factor SPX PF03105.14 KOS17022.1 - 0.00097 18.9 0.9 0.0014 18.5 0.6 1.3 1 0 0 1 1 1 1 SPX domain CNTF PF01110.12 KOS17022.1 - 0.018 14.3 0.3 0.027 13.7 0.2 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor dsrm PF00035.20 KOS17022.1 - 0.061 13.8 0.0 0.31 11.6 0.0 2.2 2 0 0 2 2 2 0 Double-stranded RNA binding motif Fmp27_WPPW PF10359.4 KOS17022.1 - 4 5.7 10.6 5.5 5.2 7.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain F-box PF00646.28 KOS17024.1 - 6.2e-05 22.5 0.3 0.00016 21.2 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KOS17024.1 - 0.00026 20.6 0.5 0.00091 18.9 0.3 2.0 1 0 0 1 1 1 1 F-box-like DUF4345 PF14248.1 KOS17026.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) FAD_binding_4 PF01565.18 KOS17027.1 - 4e-16 58.7 0.0 6.8e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DEAD PF00270.24 KOS17028.1 - 9.2e-44 148.9 0.1 2.6e-43 147.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KOS17028.1 - 8.5e-23 79.6 1.8 8.9e-23 79.6 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KOS17028.1 - 3.5e-21 74.8 0.0 7.7e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pox_Ag35 PF03286.9 KOS17028.1 - 0.41 10.1 9.9 0.68 9.4 6.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.1 KOS17028.1 - 3.5 7.3 5.7 7 6.3 4.0 1.5 1 0 0 1 1 1 0 FAM176 family Daxx PF03344.10 KOS17028.1 - 7.3 4.9 12.2 11 4.3 8.4 1.2 1 0 0 1 1 1 0 Daxx Family Aa_trans PF01490.13 KOS17029.1 - 1.8e-51 174.9 39.8 2e-51 174.7 27.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NOB1_Zn_bind PF08772.6 KOS17030.1 - 3.1e-32 110.2 4.1 5.6e-32 109.4 2.8 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 KOS17030.1 - 0.00029 20.6 7.5 0.00029 20.6 5.2 2.2 2 1 0 2 2 2 1 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 KOS17030.1 - 0.0049 16.3 0.5 0.014 14.9 0.4 1.8 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain HypA PF01155.14 KOS17030.1 - 0.083 12.5 0.1 5.8 6.6 1.2 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family tRNA-synt_1e PF01406.14 KOS17031.1 - 1.2e-114 382.4 0.0 1.7e-114 382.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KOS17031.1 - 5.9e-06 25.1 0.2 0.081 11.5 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.6 KOS17031.1 - 0.038 14.2 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 DALR domain DUF883 PF05957.8 KOS17031.1 - 0.53 10.7 8.1 3.4 8.1 0.0 3.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) GCD14 PF08704.5 KOS17032.1 - 1.5e-60 204.8 1.0 1.8e-57 194.6 0.0 3.3 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 KOS17032.1 - 0.0016 18.4 0.1 0.0046 16.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS17032.1 - 0.038 14.5 0.0 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.11 KOS17033.1 - 1.1e-31 109.9 30.8 1.1e-31 109.9 21.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PgaD PF13994.1 KOS17033.1 - 0.11 11.9 3.4 0.35 10.3 0.0 3.0 3 1 1 4 4 4 0 PgaD-like protein Herpes_gE PF02480.11 KOS17033.1 - 0.28 9.3 0.0 0.48 8.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3759 PF12585.3 KOS17034.1 - 1.1e-26 92.5 10.1 1.3e-26 92.3 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Peptidase_C32 PF05411.7 KOS17034.1 - 0.00096 18.8 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Equine arteritis virus putative proteinase DUF1294 PF06961.8 KOS17034.1 - 0.051 13.5 0.8 7.3 6.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1294) MS_channel PF00924.13 KOS17036.1 - 9e-19 67.6 0.3 1.6e-18 66.8 0.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KOS17036.1 - 0.00027 20.0 0.5 0.00066 18.8 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KOS17036.1 - 0.0092 15.7 0.1 0.031 14.1 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KOS17036.1 - 0.0095 15.2 0.0 0.031 13.6 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KOS17036.1 - 0.046 13.8 0.1 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.1 KOS17036.1 - 0.059 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair Abhydrolase_9_N PF15420.1 KOS17036.1 - 5.8 6.5 9.5 0.26 11.0 0.9 2.6 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus BRCT PF00533.21 KOS17037.1 - 1.7e-07 31.2 0.0 4.3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Glyco_trans_1_4 PF13692.1 KOS17037.1 - 0.023 14.8 0.1 0.073 13.2 0.0 1.8 1 1 1 2 2 2 0 Glycosyl transferases group 1 LSM PF01423.17 KOS17039.1 - 1.9e-06 27.3 0.1 2.9e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 LSM domain Iron_permease PF04120.7 KOS17041.1 - 1.1e-39 134.9 8.4 2.6e-20 72.3 0.0 4.2 4 0 0 4 4 4 4 Low affinity iron permease DUF2839 PF10999.3 KOS17041.1 - 0.0097 15.9 0.2 0.0097 15.9 0.2 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2839) PBS_linker_poly PF00427.16 KOS17041.1 - 0.013 15.1 0.2 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide DUF3353 PF11833.3 KOS17041.1 - 0.14 11.5 5.6 3.3 7.1 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3353) DUF4149 PF13664.1 KOS17041.1 - 0.27 11.3 0.1 0.27 11.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) DUF4173 PF13777.1 KOS17041.1 - 1.1 8.5 15.5 2.7 7.2 0.5 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4173) Nop10p PF04135.7 KOS17042.1 - 3.4e-20 71.5 0.0 4e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family YkuD_2 PF13645.1 KOS17042.1 - 0.039 13.1 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain SAM_decarbox PF01536.11 KOS17043.1 - 5.2e-28 97.6 0.0 1.4e-26 92.9 0.0 2.4 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase ParA PF10609.4 KOS17045.1 - 1.9e-36 123.8 0.0 3.8e-36 122.8 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KOS17045.1 - 4.8e-06 26.1 0.0 9.4e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Glyoxal_oxid_N PF07250.6 KOS17046.1 - 0.13 11.2 0.6 0.15 11.0 0.4 1.1 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus NMO PF03060.10 KOS17048.1 - 3.9e-67 226.7 0.6 4.6e-67 226.5 0.4 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KOS17048.1 - 1.9e-06 27.0 0.1 0.0003 19.7 0.1 2.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KOS17048.1 - 0.002 17.0 9.5 0.003 16.4 6.6 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NTF2 PF02136.15 KOS17049.1 - 0.0045 17.3 0.6 0.024 15.0 0.4 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 KOS17049.1 - 0.093 12.4 0.0 1.6 8.4 0.0 1.9 1 1 0 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 PPTA PF01239.17 KOS17051.1 - 5e-43 142.6 7.9 1.1e-08 34.0 0.1 6.1 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF1148 PF06618.6 KOS17051.1 - 0.031 14.2 0.7 10 6.1 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1148) TPR_14 PF13428.1 KOS17051.1 - 0.16 12.6 0.2 0.16 12.6 0.1 4.8 4 1 2 6 6 6 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.21 KOS17052.1 - 4.7e-19 68.2 0.0 9.8e-19 67.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KOS17052.1 - 3.5e-09 36.7 0.0 9.1e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Ribosomal_L38e PF01781.13 KOS17053.1 - 1.1e-33 114.7 2.9 1.2e-33 114.6 2.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family pRN1_helical PF13010.1 KOS17053.1 - 0.18 11.4 2.4 0.25 10.9 1.4 1.4 1 1 0 1 1 1 0 Primase helical domain Pkinase PF00069.20 KOS17055.1 - 7.1e-40 136.7 0.0 9e-40 136.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17055.1 - 2.5e-13 49.6 0.0 4.2e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KOS17055.1 - 0.074 12.1 0.2 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KOS17055.1 - 0.12 12.0 0.3 0.12 12.0 0.2 2.6 1 1 2 3 3 3 0 Phosphotransferase enzyme family Acetyltransf_3 PF13302.1 KOS17056.1 - 2.7e-20 72.9 0.0 5.2e-20 72.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KOS17056.1 - 1.6e-06 28.0 0.4 0.022 14.6 0.0 3.0 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS17056.1 - 0.0012 18.8 0.1 0.03 14.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KOS17056.1 - 0.0039 16.9 0.2 1.8 8.3 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein tRNA-synt_1g PF09334.6 KOS17057.1 - 1.2e-115 386.3 0.4 1.6e-115 385.9 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KOS17057.1 - 3.2e-23 81.6 4.8 6.3e-11 40.9 0.1 3.2 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KOS17057.1 - 2.8e-08 33.2 0.0 0.0052 15.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 KOS17057.1 - 0.029 14.1 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Peripla_BP_3 PF13377.1 KOS17057.1 - 0.049 13.6 0.0 0.41 10.6 0.0 2.3 1 1 1 2 2 2 0 Periplasmic binding protein-like domain Peptidase_C28 PF05408.6 KOS17057.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase DALR_2 PF09190.6 KOS17057.1 - 0.22 11.8 1.8 0.55 10.5 0.6 2.2 2 1 0 2 2 2 0 DALR domain SCRL PF06876.7 KOS17058.1 - 6.4 6.8 7.8 0.95 9.4 2.6 1.7 1 1 1 2 2 2 0 Plant self-incompatibility response (SCRL) protein Porphobil_deam PF01379.15 KOS17059.1 - 7.8e-77 257.0 0.0 1e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KOS17059.1 - 1.4e-17 63.5 0.6 3.1e-17 62.4 0.2 1.8 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain DUF2604 PF10790.4 KOS17059.1 - 0.11 12.6 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of Unknown function (DUF2604) Fungal_trans PF04082.13 KOS17061.1 - 3.1e-09 36.0 1.6 4.9e-09 35.4 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KOS17062.1 - 2.1e-12 47.2 0.1 3.3e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS17062.1 - 0.017 14.7 0.1 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 KR domain p450 PF00067.17 KOS17063.1 - 2.8e-29 101.9 0.0 3.9e-29 101.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_3 PF00933.16 KOS17064.1 - 3.8e-83 278.8 0.0 5.5e-83 278.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KOS17064.1 - 2.5e-54 184.1 0.8 2.6e-53 180.8 0.1 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KOS17064.1 - 3e-23 81.5 0.1 5.8e-23 80.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.6 KOS17064.1 - 0.0074 16.3 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 CARDB DUF11 PF01345.13 KOS17064.1 - 1.5 8.8 7.0 14 5.7 1.6 3.0 1 1 1 2 2 2 0 Domain of unknown function DUF11 CH PF00307.26 KOS17065.1 - 2.3e-12 46.9 0.0 3.8e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KOS17065.1 - 0.034 13.7 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain NDUFA12 PF05071.11 KOS17066.1 - 2.5e-09 37.5 2.6 8.4e-08 32.6 0.5 2.4 2 0 0 2 2 2 2 NADH ubiquinone oxidoreductase subunit NDUFA12 tRNA_int_endo PF01974.12 KOS17067.1 - 3.6e-19 68.3 0.0 7.5e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KOS17067.1 - 3.4e-05 23.2 0.0 0.041 13.4 0.0 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain zf-C2H2_jaz PF12171.3 KOS17068.1 - 1.6e-31 107.6 30.4 0.00042 20.3 0.2 11.1 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS17068.1 - 3.6e-30 103.1 36.8 0.00027 21.0 0.1 11.4 12 0 0 12 12 11 7 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KOS17068.1 - 8.8e-25 85.1 31.0 0.023 14.9 0.0 11.4 11 0 0 11 11 11 8 C2H2-type zinc finger zf-C2H2 PF00096.21 KOS17068.1 - 3.2e-24 83.7 32.5 0.0022 18.2 0.3 11.3 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KOS17068.1 - 1.7e-11 43.5 36.0 0.0018 18.1 0.3 8.7 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KOS17068.1 - 2.5e-11 43.5 42.0 0.07 13.2 0.6 9.0 3 1 6 9 9 9 8 C2H2 type zinc-finger (2 copies) PAT1 PF09770.4 KOS17068.1 - 0.0086 14.3 22.2 0.011 14.0 15.4 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Baculo_IE-1 PF05290.6 KOS17068.1 - 0.51 10.0 7.6 8.5 6.0 0.0 5.0 4 2 0 4 4 4 0 Baculovirus immediate-early protein (IE-0) zf-H2C2_2 PF13465.1 KOS17068.1 - 1.8 9.0 49.8 0.92 9.9 2.2 10.0 11 1 0 11 11 10 0 Zinc-finger double domain zf-met2 PF12907.2 KOS17068.1 - 2.6 8.0 24.4 5.9 6.9 1.0 7.4 8 0 0 8 8 8 0 Zinc-binding Med15 PF09606.5 KOS17068.1 - 4.8 5.2 37.3 0.12 10.5 21.3 1.6 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-C2HC_2 PF13913.1 KOS17068.1 - 9.7 5.9 32.7 0.78 9.4 0.2 7.9 8 1 0 8 8 8 0 zinc-finger of a C2HC-type CarbpepA_inh PF02977.10 KOS17071.1 - 0.54 9.8 6.7 2.3 7.8 4.6 1.9 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor PLATZ PF04640.9 KOS17071.1 - 0.72 10.1 5.0 18 5.6 2.6 2.2 1 1 1 2 2 2 0 PLATZ transcription factor PsaN PF05479.6 KOS17072.1 - 0.051 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Glucosamine_iso PF01182.15 KOS17073.1 - 9.4e-60 201.7 0.0 1.1e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase TPR_11 PF13414.1 KOS17074.1 - 0.00061 19.3 0.9 0.84 9.3 0.2 2.8 2 0 0 2 2 2 2 TPR repeat SET PF00856.23 KOS17074.1 - 0.00098 19.4 0.4 0.0093 16.2 0.1 2.5 2 1 0 2 2 2 1 SET domain TPR_14 PF13428.1 KOS17074.1 - 0.99 10.2 6.6 13 6.7 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat zf-MYND PF01753.13 KOS17074.1 - 2.4 8.1 9.2 0.09 12.6 1.5 2.2 2 0 0 2 2 2 0 MYND finger ADH_N PF08240.7 KOS17075.1 - 5.8e-06 26.0 0.0 3.1e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KOS17075.1 - 0.032 13.7 1.0 0.11 12.0 0.2 2.0 1 1 1 2 2 2 0 Zinc-binding dehydrogenase DUF3759 PF12585.3 KOS17076.1 - 1.1e-35 121.3 5.5 1.4e-35 121.0 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF2648 PF10855.3 KOS17076.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) DUF2414 PF10309.4 KOS17076.1 - 0.098 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) NDK PF00334.14 KOS17077.1 - 2.3e-54 182.8 0.0 2.7e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 KOS17078.1 - 8e-155 515.9 2.0 1.2e-154 515.4 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KOS17078.1 - 4.4e-24 84.1 0.1 1.2e-23 82.7 0.1 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like FLILHELTA PF10306.4 KOS17080.1 - 5.2e-28 96.9 0.0 7.9e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 KOS17080.1 - 0.0013 19.0 0.1 0.0018 18.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) E1-E2_ATPase PF00122.15 KOS17081.1 - 1.3e-21 76.7 0.1 2.1e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KOS17081.1 - 1.2e-19 71.2 0.2 3.9e-19 69.5 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS17081.1 - 4.2e-15 56.7 3.0 1.5e-13 51.6 2.1 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS17081.1 - 1.7e-10 40.6 0.0 4.8e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KOS17081.1 - 0.0014 18.3 0.5 0.0053 16.3 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mt_ATP-synt_B PF05405.9 KOS17081.1 - 0.043 13.2 0.1 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Glyco_hydro_18 PF00704.23 KOS17082.1 - 1.9e-12 47.2 0.0 3.8e-12 46.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Abhydrolase_6 PF12697.2 KOS17083.1 - 7.2e-31 107.8 5.8 1e-30 107.3 4.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS17083.1 - 5.5e-15 55.5 0.0 1.1e-13 51.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS17083.1 - 2.4e-11 43.5 0.0 8.3e-11 41.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KOS17083.1 - 0.0038 16.1 0.0 0.0057 15.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 KOS17083.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Chlorophyllase PF07224.6 KOS17083.1 - 0.046 12.4 0.0 0.077 11.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Cript PF10235.4 KOS17084.1 - 4e-05 23.8 0.4 4e-05 23.8 0.3 1.8 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DUF1688 PF07958.6 KOS17085.1 - 5e-176 585.3 0.0 5.7e-176 585.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) zf-FCS PF06467.9 KOS17086.1 - 0.051 13.2 0.3 0.11 12.1 0.2 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif TOM13 PF08219.6 KOS17087.1 - 2.6e-29 100.7 0.0 3.3e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.15 KOS17088.1 - 4.8e-22 78.6 1.3 8.2e-22 77.8 0.9 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein DUF3597 PF12200.3 KOS17088.1 - 8.7 6.7 11.6 14 6.0 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Gtr1_RagA PF04670.7 KOS17089.1 - 4.3e-90 300.9 0.0 5.3e-90 300.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KOS17089.1 - 5.2e-09 35.6 0.0 8.9e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KOS17089.1 - 4.5e-08 32.5 0.0 6.7e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KOS17089.1 - 1.3e-05 25.7 0.0 2.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KOS17089.1 - 1.5e-05 24.8 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 KOS17089.1 - 0.0012 18.3 0.9 0.0051 16.3 0.2 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KOS17089.1 - 0.0054 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter DUF815 PF05673.8 KOS17089.1 - 0.016 14.1 0.0 0.035 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) G-alpha PF00503.15 KOS17089.1 - 0.038 12.6 0.3 0.35 9.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit DUF258 PF03193.11 KOS17089.1 - 0.052 12.7 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 KOS17089.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.13 KOS17089.1 - 0.12 11.8 0.1 1.6 8.1 0.0 2.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KOS17089.1 - 0.13 11.3 0.0 0.33 9.9 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin SEP PF08059.8 KOS17090.1 - 4.1e-27 94.2 0.0 7.6e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 KOS17090.1 - 5.6e-11 41.8 1.3 8.6e-11 41.1 0.9 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KOS17090.1 - 1.3e-09 38.0 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.8 KOS17090.1 - 0.015 14.6 0.9 0.024 14.0 0.6 1.3 1 0 0 1 1 1 0 TAP C-terminal domain UBA PF00627.26 KOS17090.1 - 0.091 12.6 0.5 0.19 11.6 0.4 1.4 1 0 0 1 1 1 0 UBA/TS-N domain TrkH PF02386.11 KOS17091.1 - 1.1e-64 218.2 12.3 4e-62 209.8 0.5 2.6 2 1 0 2 2 2 2 Cation transport protein SPOB_a PF14689.1 KOS17092.1 - 0.00023 20.6 2.7 0.27 10.8 0.1 2.4 2 0 0 2 2 2 2 Sensor_kinase_SpoOB-type, alpha-helical domain Med15 PF09606.5 KOS17092.1 - 0.032 12.4 21.3 0.034 12.3 14.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SAGA-Tad1 PF12767.2 KOS17092.1 - 0.25 10.9 9.0 0.28 10.8 6.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Suf PF05843.9 KOS17092.1 - 0.31 10.7 6.0 0.3 10.7 4.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.3 KOS17092.1 - 0.5 9.0 25.0 0.6 8.8 17.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 eIF-3_zeta PF05091.7 KOS17092.1 - 0.82 8.2 8.2 0.85 8.1 5.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.8 KOS17092.1 - 0.92 8.9 3.8 1 8.8 2.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RR_TM4-6 PF06459.7 KOS17092.1 - 3.3 7.5 5.5 3.8 7.3 3.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 KOS17092.1 - 9.1 4.1 8.5 11 3.8 5.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Glyco_transf_21 PF13506.1 KOS17093.1 - 1.2e-12 47.4 0.0 1.7e-06 27.3 0.0 3.6 2 1 1 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KOS17093.1 - 4.8e-10 39.6 0.1 1e-09 38.5 0.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KOS17093.1 - 0.00017 21.3 0.0 0.0008 19.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Sugar_tr PF00083.19 KOS17094.1 - 2.9e-33 115.1 30.0 1.1e-32 113.2 20.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS17094.1 - 9.4e-32 110.0 55.6 2.9e-29 101.8 23.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zw10 PF06248.8 KOS17096.1 - 1.4e-14 53.2 1.2 6.5e-06 24.5 1.6 3.1 3 0 0 3 3 3 3 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 KOS17096.1 - 0.81 8.7 8.5 0.082 12.0 0.5 2.8 2 1 0 2 2 2 0 Retrograde transport protein Dsl1 C terminal GBP_C PF02841.9 KOS17096.1 - 1.5 7.8 9.3 0.28 10.3 0.5 2.5 3 0 0 3 3 3 0 Guanylate-binding protein, C-terminal domain PI-PLC-X PF00388.14 KOS17097.1 - 2.8e-58 195.4 0.0 5.2e-58 194.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KOS17097.1 - 3.3e-38 130.3 0.2 1.3e-37 128.4 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KOS17097.1 - 9.2e-05 22.3 0.1 0.00044 20.2 0.0 2.1 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like Mcp5_PH PF12814.2 KOS17097.1 - 0.033 14.1 0.6 0.084 12.7 0.4 1.6 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Peptidase_M48 PF01435.13 KOS17098.1 - 2.5e-51 174.4 0.4 3.9e-51 173.7 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 KOS17098.1 - 1.9e-05 23.8 0.1 3e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF4538 PF15061.1 KOS17098.1 - 0.015 14.5 0.5 0.032 13.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Flavin_Reduct PF01613.13 KOS17098.1 - 0.026 14.3 0.0 0.067 13.0 0.0 1.7 1 0 0 1 1 1 0 Flavin reductase like domain DUF955 PF06114.8 KOS17098.1 - 0.087 12.5 0.2 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF955) Peptidase_M16_C PF05193.16 KOS17099.1 - 2e-17 63.4 0.0 1.4e-12 47.6 0.0 3.5 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KOS17099.1 - 1.6e-07 31.2 0.1 1.2e-05 25.1 0.0 3.0 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.6 KOS17099.1 - 0.31 9.8 1.4 15 4.3 1.2 2.3 2 0 0 2 2 2 0 Peptidase M16C associated M16C_assoc PF08367.6 KOS17100.1 - 1.9e-59 200.5 0.0 4.5e-59 199.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 KOS17100.1 - 8.3e-33 113.6 0.0 4.5e-19 68.8 0.0 3.4 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KOS17100.1 - 0.0021 17.8 0.2 0.16 11.7 0.2 3.2 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Taxilin PF09728.4 KOS17101.1 - 1.1e-82 277.5 59.8 1.1e-82 277.5 41.5 1.9 2 0 0 2 2 2 1 Myosin-like coiled-coil protein TSC22 PF01166.13 KOS17101.1 - 4.2 7.4 20.3 14 5.7 0.6 4.8 3 1 1 4 4 4 0 TSC-22/dip/bun family Glyco_hydro_67N PF03648.9 KOS17101.1 - 8.7 6.4 9.7 1.4 8.9 1.0 2.7 2 1 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus SNF2_N PF00176.18 KOS17102.1 - 1.1e-45 155.7 0.0 2.1e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 KOS17102.1 - 1.5e-06 27.7 11.3 1.5e-06 27.7 7.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 KOS17102.1 - 2.1e-06 27.4 0.0 4.7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 KOS17102.1 - 0.00057 19.6 12.8 0.00057 19.6 8.8 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KOS17102.1 - 0.0013 18.7 11.7 0.0013 18.7 8.1 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS17102.1 - 0.002 17.7 11.2 0.002 17.7 7.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KOS17102.1 - 0.23 11.2 10.5 0.072 12.8 3.7 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Zn_Tnp_IS91 PF14319.1 KOS17102.1 - 3.9 7.0 14.8 9 5.8 4.4 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain Orn_Arg_deC_N PF02784.11 KOS17103.1 - 4.4e-76 255.3 0.0 6.6e-76 254.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KOS17103.1 - 2.3e-28 98.2 0.1 4e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain zf-DHHC PF01529.15 KOS17104.1 - 7.9e-44 149.1 3.7 7.9e-44 149.1 2.6 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 KOS17104.1 - 0.1 12.4 6.4 0.19 11.5 4.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.21 KOS17105.1 - 6.5e-05 23.0 9.3 5.8 7.4 0.0 5.5 5 0 0 5 5 5 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KOS17105.1 - 0.0016 18.2 7.9 0.016 15.0 0.2 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-Di19 PF05605.7 KOS17105.1 - 0.0029 17.7 9.5 0.041 14.0 0.4 3.7 3 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KOS17105.1 - 0.0049 17.1 9.6 21 5.7 0.4 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger IBR PF01485.16 KOS17105.1 - 0.005 16.6 2.0 0.029 14.2 0.1 2.8 3 0 0 3 3 3 1 IBR domain zf-C2H2_jaz PF12171.3 KOS17105.1 - 0.029 14.4 1.1 3.4 7.9 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KOS17105.1 - 0.066 13.3 6.8 34 4.6 0.1 4.7 3 2 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KOS17105.1 - 0.1 12.8 1.1 18 5.6 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF2752 PF10825.3 KOS17105.1 - 0.29 11.1 3.4 1.5 8.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) DZR PF12773.2 KOS17105.1 - 0.5 10.2 6.2 0.86 9.4 0.2 2.9 3 0 0 3 3 3 0 Double zinc ribbon zf-4CXXC_R1 PF10497.4 KOS17105.1 - 0.55 10.3 3.9 1.7 8.7 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 ATPase-cat_bd PF12156.3 KOS17105.1 - 1.4 9.4 4.1 17 6.0 0.1 2.7 2 1 1 3 3 3 0 Putative metal-binding domain of cation transport ATPase zf-TFIIB PF13453.1 KOS17105.1 - 1.7 7.8 9.3 2.2 7.5 0.3 2.8 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-H2C2_2 PF13465.1 KOS17105.1 - 6.2 7.3 16.3 0.27 11.6 0.5 4.3 5 0 0 5 5 4 0 Zinc-finger double domain Pkinase PF00069.20 KOS17106.1 - 1.2e-59 201.5 0.1 2e-59 200.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17106.1 - 2.8e-20 72.5 0.0 4.4e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS17106.1 - 2.2e-07 30.1 0.0 3.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PAS_9 PF13426.1 KOS17106.1 - 0.0042 17.4 0.0 0.92 9.9 0.0 3.4 3 1 0 3 3 3 1 PAS domain APH PF01636.18 KOS17106.1 - 0.0081 15.9 0.1 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KOS17106.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family CBS PF00571.23 KOS17108.1 - 2.3e-31 107.3 6.5 2.3e-13 49.6 0.1 4.3 4 0 0 4 4 4 4 CBS domain MARVEL PF01284.18 KOS17109.1 - 1.6e-06 27.9 11.3 2.6e-06 27.3 7.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain Erf4 PF10256.4 KOS17109.1 - 0.012 15.5 1.7 0.015 15.1 0.4 1.9 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family DUF3449 PF11931.3 KOS17111.1 - 9.6e-72 240.6 0.4 9.6e-72 240.6 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 KOS17111.1 - 1.2e-08 34.3 0.1 2.3e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 KOS17111.1 - 2.7e-08 33.7 3.3 4.1e-06 26.7 0.4 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KOS17111.1 - 1.2e-06 28.4 0.7 1.2e-06 28.4 0.5 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KOS17111.1 - 0.0016 18.4 0.8 0.14 12.2 0.3 2.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF951 PF06107.6 KOS17111.1 - 0.018 14.5 0.0 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) DUF2338 PF10100.4 KOS17111.1 - 0.12 10.7 0.0 0.19 10.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) zf-U1 PF06220.7 KOS17111.1 - 0.14 11.7 0.7 0.36 10.4 0.5 1.7 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2 PF00096.21 KOS17111.1 - 0.23 11.8 4.4 1.9 8.9 0.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS17111.1 - 0.62 10.5 3.6 5.7 7.5 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Ank_2 PF12796.2 KOS17112.1 - 8.6e-23 80.4 1.6 1.3e-13 51.1 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KOS17112.1 - 1.5e-14 53.6 0.4 2.7e-07 30.6 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KOS17112.1 - 3.8e-14 52.7 1.2 1.7e-06 28.3 0.1 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KOS17112.1 - 3.9e-14 51.6 1.3 2.9e-08 33.0 0.3 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KOS17112.1 - 2.9e-09 36.2 0.0 0.0016 18.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat PARP_reg PF02877.9 KOS17113.1 - 8.6e-37 125.7 0.0 1.5e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain PARP PF00644.15 KOS17113.1 - 1.6e-32 112.6 0.5 1.5e-25 89.8 0.0 2.9 2 1 1 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain WGR PF05406.10 KOS17113.1 - 2.3e-21 75.5 0.3 4.7e-21 74.5 0.2 1.5 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 KOS17113.1 - 2.3e-12 46.8 0.0 1e-11 44.8 0.0 2.1 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KOS17113.1 - 1.3e-09 37.7 0.2 3.1e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain DUF2361 PF10153.4 KOS17114.1 - 1.5e-30 105.7 8.4 1.5e-30 105.7 5.8 2.9 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) Collagen PF01391.13 KOS17114.1 - 0.12 11.9 6.7 0.044 13.3 2.3 1.9 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) IER PF05760.7 KOS17115.1 - 0.0035 17.3 3.6 0.0063 16.4 2.5 1.4 1 0 0 1 1 1 1 Immediate early response protein (IER) Senescence_reg PF04520.8 KOS17115.1 - 0.43 11.0 4.6 0.19 12.2 0.9 2.1 2 0 0 2 2 2 0 Senescence regulator DUF4611 PF15387.1 KOS17115.1 - 1.4 9.0 7.6 2.6 8.2 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) BTB PF00651.26 KOS17116.1 - 0.00071 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain TauD PF02668.11 KOS17117.1 - 8e-38 130.5 0.0 1.1e-37 130.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KOS17117.1 - 0.046 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF971) SGS PF05002.10 KOS17118.1 - 1.8e-25 88.4 1.0 1.8e-25 88.4 0.7 1.7 2 0 0 2 2 2 1 SGS domain CS PF04969.11 KOS17118.1 - 2.3e-12 47.2 0.1 3.9e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 KOS17118.1 - 1.4e-05 24.6 10.1 0.00021 20.8 0.2 2.6 1 1 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 KOS17118.1 - 0.00025 21.6 17.6 0.0016 19.0 0.8 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KOS17118.1 - 0.0011 18.7 6.8 3.6 7.7 1.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KOS17118.1 - 0.56 9.9 8.8 0.35 10.5 3.5 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KOS17118.1 - 2.1 9.2 11.6 2.5 8.9 0.2 3.7 2 1 0 3 3 3 0 Tetratricopeptide repeat PTS_2-RNA PF01885.11 KOS17119.1 - 1.9e-60 203.3 0.0 2.4e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DSPc PF00782.15 KOS17120.1 - 5.5e-26 90.7 0.0 2.3e-24 85.4 0.0 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KOS17120.1 - 0.0015 17.8 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DNA_pol3_chi PF04364.8 KOS17120.1 - 0.09 12.6 0.0 8.2 6.2 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III chi subunit, HolC PTPlike_phytase PF14566.1 KOS17120.1 - 0.11 12.4 0.0 0.71 9.9 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.7 KOS17120.1 - 0.12 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) UAA PF08449.6 KOS17121.1 - 3.8e-72 242.7 3.9 9.4e-72 241.4 2.7 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KOS17121.1 - 8.9e-07 28.9 31.2 3.5e-06 27.0 4.8 3.5 4 1 0 4 4 4 3 EamA-like transporter family Nuc_sug_transp PF04142.10 KOS17121.1 - 3.5e-06 26.3 2.8 0.019 14.0 0.3 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 KOS17121.1 - 2.6e-05 24.3 23.4 0.00011 22.3 5.6 3.6 2 2 2 4 4 4 2 Multidrug resistance efflux transporter TPT PF03151.11 KOS17121.1 - 0.00048 19.8 5.2 0.00048 19.8 3.6 2.6 3 0 0 3 3 3 1 Triose-phosphate Transporter family KH_1 PF00013.24 KOS17122.1 - 1e-38 130.7 12.7 4.3e-15 55.0 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KOS17122.1 - 5.8e-30 102.4 12.9 5.7e-11 41.8 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KOS17122.1 - 2.1e-09 36.8 9.9 0.014 14.9 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KOS17122.1 - 5.8e-08 32.2 4.6 0.054 13.1 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KOS17122.1 - 0.0002 21.0 4.6 0.54 10.0 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 KOS17122.1 - 0.0035 16.8 0.3 0.52 9.7 0.0 3.1 3 0 0 3 3 3 1 dUTPase Homeobox PF00046.24 KOS17124.1 - 5.4e-20 70.7 4.2 1.2e-19 69.6 2.9 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KOS17124.1 - 0.00027 20.5 0.4 0.00099 18.7 0.3 2.0 1 0 0 1 1 1 1 Homeobox KN domain Adaptin_binding PF10199.4 KOS17125.1 - 7.1e-12 45.7 5.9 2.5e-11 43.9 4.1 1.9 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DUF4386 PF14329.1 KOS17126.1 - 0.02 14.3 0.5 0.031 13.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) Serglycin PF04360.7 KOS17126.1 - 0.29 10.8 0.1 0.29 10.8 0.1 1.7 2 0 0 2 2 2 0 Serglycin Prenyltrans PF00432.16 KOS17127.1 - 1.5e-29 101.2 13.6 2.5e-09 36.5 0.4 5.9 4 2 1 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 KOS17127.1 - 1.2e-25 89.6 0.4 3.5e-12 46.2 0.4 5.7 5 1 1 6 6 6 3 Prenyltransferase-like Prenyltrans_2 PF13249.1 KOS17127.1 - 1.8e-25 89.5 2.5 1.1e-17 64.4 0.5 4.7 4 1 0 4 4 4 3 Prenyltransferase-like Pec_lyase PF09492.5 KOS17127.1 - 1.2e-05 24.6 0.7 0.26 10.3 0.0 4.2 4 2 0 4 4 4 2 Pectic acid lyase A2M_comp PF07678.9 KOS17127.1 - 0.0051 16.0 0.6 0.49 9.5 0.1 3.6 3 1 2 5 5 5 1 A-macroglobulin complement component Mago-bind PF09282.5 KOS17127.1 - 0.11 12.0 0.2 0.53 9.8 0.1 2.1 2 0 0 2 2 2 0 Mago binding ketoacyl-synt PF00109.21 KOS17128.1 - 3e-65 220.2 0.9 1.1e-64 218.4 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KOS17128.1 - 2.8e-60 203.0 0.6 1.3e-59 200.9 0.2 2.3 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 KOS17128.1 - 1.5e-57 195.3 0.0 2.5e-57 194.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KOS17128.1 - 2.1e-47 161.1 2.3 7e-47 159.4 0.2 2.6 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 KOS17128.1 - 1.6e-37 129.2 0.0 5e-37 127.6 0.0 1.9 1 1 1 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KOS17128.1 - 2.9e-31 107.7 0.3 7.7e-31 106.4 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KOS17128.1 - 7.7e-21 74.0 0.4 6.5e-20 70.9 0.0 2.8 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KOS17128.1 - 1.7e-17 63.7 0.0 5.9e-17 61.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KOS17128.1 - 1.9e-14 54.6 0.0 8.8e-14 52.4 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KOS17128.1 - 6.6e-13 48.7 0.0 2.2e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS17128.1 - 2.3e-09 36.9 0.0 4.8e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KOS17128.1 - 3e-09 36.6 0.0 7.5e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 KOS17128.1 - 1.1e-08 35.6 0.0 3.1e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS17128.1 - 1.2e-07 32.0 0.0 5.2e-07 30.0 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS17128.1 - 6.3e-05 23.2 0.0 0.00031 21.0 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KOS17128.1 - 0.00029 20.0 0.0 0.00059 19.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KOS17128.1 - 0.014 15.4 0.0 0.048 13.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Thiolase_N PF00108.18 KOS17128.1 - 0.015 14.2 0.1 0.035 13.0 0.1 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain PCMT PF01135.14 KOS17128.1 - 0.028 13.9 0.1 0.07 12.6 0.0 1.6 2 0 0 2 2 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PP-binding PF00550.20 KOS17128.1 - 0.13 12.5 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site Methyltransf_16 PF10294.4 KOS17128.1 - 0.32 10.4 0.0 0.84 9.0 0.0 1.6 2 0 0 2 2 1 0 Putative methyltransferase RrnaAD PF00398.15 KOS17128.1 - 0.48 9.4 0.0 0.96 8.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase UQ_con PF00179.21 KOS17129.1 - 5.9e-51 171.5 0.0 6.7e-51 171.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TPR_11 PF13414.1 KOS17130.1 - 8.7e-12 44.5 0.7 4.1e-10 39.1 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 KOS17130.1 - 1.6e-07 30.7 0.0 0.17 11.8 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KOS17130.1 - 2.3e-05 24.2 0.4 0.00032 20.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KOS17130.1 - 2.5e-05 23.7 0.0 0.53 9.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.26 KOS17130.1 - 0.00056 19.6 0.0 0.0019 18.0 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain TPR_4 PF07721.9 KOS17130.1 - 0.0018 18.5 0.2 4.1 8.1 0.0 3.8 2 0 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.26 KOS17130.1 - 0.01 15.5 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain Voldacs PF03517.8 KOS17132.1 - 5e-17 62.0 2.7 6.2e-17 61.6 0.0 2.3 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling zf-C3HC4_3 PF13920.1 KOS17133.1 - 0.33 10.6 19.7 1.5 8.5 1.3 3.1 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS17133.1 - 0.38 10.4 18.3 0.16 11.6 5.2 3.3 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF305 PF03713.8 KOS17134.1 - 0.0084 15.9 2.4 0.012 15.4 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF305) SpoVR PF04293.8 KOS17134.1 - 0.016 13.6 0.5 0.02 13.2 0.4 1.1 1 0 0 1 1 1 0 SpoVR like protein RIC3 PF15361.1 KOS17134.1 - 5.2 7.2 6.2 4.2 7.6 1.4 2.2 2 1 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Dehydratase_hem PF13816.1 KOS17135.1 - 2.4e-102 342.1 0.2 2.8e-102 341.9 0.1 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 KOS17135.1 - 1.5e-05 25.0 1.0 0.0098 15.9 0.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) PAF-AH_p_II PF03403.8 KOS17136.1 - 5.5e-41 140.1 0.0 6e-36 123.5 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KOS17136.1 - 5.2e-10 39.2 0.0 1.7e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS17136.1 - 1.1e-05 25.4 0.1 2.4e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KOS17136.1 - 0.028 13.3 0.0 0.062 12.1 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 KOS17136.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.3 KOS17136.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Glyco_hydro_31 PF01055.21 KOS17137.1 - 2.5e-81 273.7 0.0 3.1e-81 273.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KOS17137.1 - 4.5e-16 58.4 0.7 1.2e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like MFS_1 PF07690.11 KOS17138.1 - 1.2e-32 113.0 31.2 1.2e-32 113.0 21.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4133 PF13571.1 KOS17138.1 - 0.13 12.5 1.9 2 8.6 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Homeobox_KN PF05920.6 KOS17139.1 - 2.5e-15 55.9 0.1 2.5e-15 55.9 0.1 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 KOS17139.1 - 1e-08 34.6 0.8 2.1e-08 33.6 0.6 1.5 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 KOS17139.1 - 2e-05 24.6 24.9 0.18 12.2 2.9 4.6 3 1 0 3 3 3 3 C2H2-type zinc finger Homez PF11569.3 KOS17139.1 - 0.0027 16.7 1.0 0.0057 15.6 0.1 1.9 1 1 1 2 2 2 1 Homeodomain leucine-zipper encoding, Homez zf-C2H2 PF00096.21 KOS17139.1 - 0.0051 17.0 4.3 0.0051 17.0 3.0 4.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KOS17139.1 - 0.045 13.8 6.9 1.6 8.8 1.2 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Sec23_Sec24 PF04810.10 KOS17139.1 - 1.3 8.6 6.5 6 6.5 0.1 3.7 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger BIR PF00653.16 KOS17139.1 - 3.4 8.1 9.8 9.9 6.6 1.5 3.9 2 1 1 3 3 3 0 Inhibitor of Apoptosis domain PALP PF00291.20 KOS17140.1 - 1.8e-52 178.5 0.2 3.2e-52 177.6 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 KOS17140.1 - 3.4e-29 101.7 0.9 7.1e-29 100.6 0.6 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KOS17140.1 - 2.3e-16 59.4 0.0 5.9e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 KOS17140.1 - 0.081 11.6 0.1 3.2 6.4 0.0 2.7 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase MFS_1 PF07690.11 KOS17141.1 - 2e-34 118.8 28.4 2e-34 118.8 19.7 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_2 PF00703.16 KOS17142.1 - 3.3e-13 50.0 0.0 1e-12 48.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KOS17142.1 - 2.4e-05 23.9 0.0 5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain N-glycanase_C PF09113.5 KOS17143.1 - 0.01 15.5 0.1 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Peptide-N-glycosidase F, C terminal Ribosomal_60s PF00428.14 KOS17144.1 - 0.089 13.2 4.0 0.18 12.2 2.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein K_channel_TID PF07941.6 KOS17144.1 - 0.17 12.0 8.3 0.058 13.6 2.1 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Glyco_hydro_12 PF01670.11 KOS17145.1 - 5.6e-18 65.2 0.0 2.7e-17 62.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_tranf_2_3 PF13641.1 KOS17146.1 - 1.8e-37 129.3 0.0 2.7e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KOS17146.1 - 9.5e-21 74.3 0.2 9.5e-21 74.3 0.1 2.9 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KOS17146.1 - 2.7e-14 53.2 0.0 4.4e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.9 KOS17146.1 - 5.4e-14 51.4 4.2 1.9e-09 36.4 2.6 3.2 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.1 KOS17146.1 - 6.5e-13 48.3 0.0 1.1e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 KOS17146.1 - 2e-05 23.2 0.0 0.0012 17.3 0.0 2.5 2 0 0 2 2 2 2 Chitin synthase ABC_tran PF00005.22 KOS17147.1 - 2.7e-51 173.4 0.0 2.1e-30 105.8 0.0 2.6 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KOS17147.1 - 3.5e-41 141.4 26.5 7.6e-24 84.5 3.5 3.6 4 0 0 4 4 3 3 ABC transporter transmembrane region SMC_N PF02463.14 KOS17147.1 - 5.4e-09 35.5 3.0 0.00064 19.0 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KOS17147.1 - 9.3e-07 29.0 0.1 0.61 10.0 0.0 3.7 4 0 0 4 4 3 3 AAA domain AAA_16 PF13191.1 KOS17147.1 - 1.5e-06 28.3 0.1 0.00088 19.3 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 KOS17147.1 - 2.4e-06 28.0 0.1 0.0027 18.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KOS17147.1 - 7.7e-06 25.4 0.0 0.19 11.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KOS17147.1 - 0.00011 21.6 0.5 0.25 10.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KOS17147.1 - 0.00017 20.6 0.0 0.067 12.0 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Zeta_toxin PF06414.7 KOS17147.1 - 0.00025 20.2 1.6 0.46 9.5 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin DUF258 PF03193.11 KOS17147.1 - 0.0049 16.0 0.1 1.4 8.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 KOS17147.1 - 0.0056 16.1 0.4 3.1 7.1 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain Miro PF08477.8 KOS17147.1 - 0.0061 17.0 0.1 5 7.6 0.1 2.7 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KOS17147.1 - 0.0067 16.3 0.4 0.18 11.7 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KOS17147.1 - 0.011 16.5 0.0 12 6.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 KOS17147.1 - 0.016 15.3 0.5 11 6.1 0.1 3.5 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 KOS17147.1 - 0.023 14.4 0.4 7.7 6.2 0.1 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KOS17147.1 - 0.027 13.9 0.2 9.3 5.6 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 KOS17147.1 - 0.046 13.9 0.5 27 4.9 0.1 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KOS17147.1 - 0.11 12.0 0.6 1.8 8.1 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF87 PF01935.12 KOS17147.1 - 0.12 12.1 1.5 0.75 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_18 PF13238.1 KOS17147.1 - 0.17 12.1 0.0 17 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KOS17147.1 - 0.27 10.9 0.0 2.2 7.8 0.0 2.3 3 0 0 3 3 2 0 Archaeal ATPase SecY PF00344.15 KOS17148.1 - 5.3e-97 324.8 11.4 7e-97 324.4 7.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KOS17148.1 - 1.7e-17 62.6 0.1 1.1e-16 60.0 0.2 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p Phage_holin_1 PF04531.8 KOS17148.1 - 5.8 7.0 7.7 12 6.0 0.0 3.7 4 2 2 6 6 6 0 Bacteriophage holin IPPT PF01715.12 KOS17149.1 - 1.1e-49 168.7 0.0 1.7e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 IPP transferase IPT PF01745.11 KOS17149.1 - 8.2e-06 25.1 0.0 3.4e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Isopentenyl transferase AAA_17 PF13207.1 KOS17149.1 - 1.8e-05 25.5 0.7 7.8e-05 23.4 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KOS17149.1 - 0.00053 19.8 0.3 0.0046 16.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain zf-C2H2_jaz PF12171.3 KOS17149.1 - 0.0023 18.0 0.1 0.0039 17.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_18 PF13238.1 KOS17149.1 - 0.003 17.8 0.2 0.026 14.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KOS17149.1 - 0.014 15.1 0.1 0.014 15.1 0.1 2.5 3 0 0 3 3 3 0 Part of AAA domain AAA_22 PF13401.1 KOS17149.1 - 0.024 14.7 0.0 0.34 11.0 0.0 2.7 2 2 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.7 KOS17149.1 - 0.025 13.8 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain SKI PF01202.17 KOS17149.1 - 0.063 13.1 0.1 5.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase zf-C2H2_2 PF12756.2 KOS17149.1 - 0.1 12.7 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AAA_5 PF07728.9 KOS17149.1 - 0.1 12.3 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) zf-met PF12874.2 KOS17149.1 - 0.22 11.7 0.5 0.39 11.0 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type AAA_16 PF13191.1 KOS17149.1 - 0.24 11.3 1.8 0.67 9.9 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain Fungal_trans PF04082.13 KOS17150.1 - 6.9e-16 57.9 0.0 1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS17150.1 - 1e-06 28.5 10.4 1.8e-06 27.7 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HypA PF01155.14 KOS17150.1 - 0.79 9.4 3.7 1.6 8.4 2.5 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family ADH_N PF08240.7 KOS17153.1 - 4.7e-30 103.5 0.2 8.7e-30 102.6 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KOS17153.1 - 1.9e-16 59.7 0.1 3e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KOS17153.1 - 0.0021 17.6 0.0 0.0047 16.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 KOS17153.1 - 0.01 16.7 0.0 0.029 15.2 0.0 1.8 1 1 1 2 2 2 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KOS17153.1 - 0.13 11.8 0.2 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RhoGAP PF00620.22 KOS17154.1 - 7.2e-10 38.6 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Pex14_N PF04695.8 KOS17154.1 - 0.076 13.0 4.3 0.16 12.0 3.0 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BAF1_ABF1 PF04684.8 KOS17154.1 - 6.9 5.4 30.3 9.2 4.9 21.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor XPC-binding PF09280.6 KOS17155.1 - 1.8e-24 84.9 10.5 3.4e-24 84.0 7.3 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 KOS17155.1 - 3.7e-18 64.7 6.5 1.5e-08 34.2 1.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 KOS17155.1 - 1.8e-17 62.4 0.3 2.8e-17 61.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KOS17155.1 - 5.6e-08 32.3 0.3 1.1e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MCM_N PF14551.1 KOS17155.1 - 0.0048 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain DUF2407 PF10302.4 KOS17155.1 - 0.0051 16.9 0.0 0.0094 16.1 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KOS17155.1 - 0.044 13.6 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 KOS17155.1 - 0.086 12.4 0.0 6 6.5 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Myb_DNA-binding PF00249.26 KOS17156.1 - 2.8e-07 30.4 0.0 5.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KOS17156.1 - 0.0023 17.9 0.4 0.006 16.6 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF1996 PF09362.5 KOS17157.1 - 9.7e-60 202.1 0.3 1.3e-59 201.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 KOS17157.1 - 4.6e-20 71.3 4.5 4.6e-20 71.3 3.1 2.2 2 0 0 2 2 2 1 WSC domain Nol1_Nop2_Fmu PF01189.12 KOS17158.1 - 3.1e-14 53.0 0.0 1.9e-09 37.3 0.0 2.6 2 1 0 2 2 2 2 NOL1/NOP2/sun family RXT2_N PF08595.6 KOS17158.1 - 0.092 12.5 4.8 0.18 11.5 3.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 KOS17158.1 - 0.12 11.6 10.1 0.19 10.9 7.0 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 KOS17158.1 - 5 6.6 21.4 8.7 5.8 14.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 KOS17158.1 - 9.6 5.7 13.9 20 4.6 9.6 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region MFS_1 PF07690.11 KOS17159.1 - 1.8e-37 128.8 52.6 2.3e-37 128.5 33.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS17159.1 - 5.9e-10 38.3 9.4 5.9e-10 38.3 6.5 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter BRE1 PF08647.6 KOS17161.1 - 8.2e-28 96.2 10.4 8.2e-28 96.2 7.2 6.7 3 3 3 6 6 5 2 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.1 KOS17161.1 - 4.1e-08 32.7 8.9 6.4e-08 32.1 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS17161.1 - 5e-08 32.4 10.3 8.8e-08 31.6 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS17161.1 - 1.6e-07 31.2 9.8 2.6e-07 30.5 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS17161.1 - 4e-06 26.4 10.2 6.6e-06 25.7 7.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KOS17161.1 - 1.1e-05 25.1 7.7 1.8e-05 24.4 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain CCDC155 PF14662.1 KOS17161.1 - 0.00031 20.4 11.4 0.00031 20.4 7.9 4.7 3 2 2 5 5 5 1 Coiled-coil region of CCDC155 zf-RING_UBOX PF13445.1 KOS17161.1 - 0.00074 19.1 5.9 0.0019 17.8 4.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 KOS17161.1 - 0.0012 18.3 2.3 0.0022 17.5 1.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DivIC PF04977.10 KOS17161.1 - 0.0027 17.1 0.5 0.0027 17.1 0.3 10.1 6 1 3 11 11 10 2 Septum formation initiator zf-RING_6 PF14835.1 KOS17161.1 - 0.012 15.3 2.3 0.024 14.4 1.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KOS17161.1 - 0.037 13.9 6.9 0.071 12.9 4.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KOS17161.1 - 0.072 12.6 6.4 0.34 10.5 4.7 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 KOS17161.1 - 1.2 9.0 11.0 13 5.7 7.7 2.3 1 1 1 2 2 2 0 FYVE zinc finger Pyrophosphatase PF00719.14 KOS17161.1 - 5.5 6.4 9.3 0.55 9.6 0.2 3.5 3 1 1 4 4 4 0 Inorganic pyrophosphatase Reo_sigmaC PF04582.7 KOS17161.1 - 6.1 5.9 35.3 0.069 12.3 3.8 4.8 2 2 3 5 5 5 0 Reovirus sigma C capsid protein DUF1183 PF06682.7 KOS17162.1 - 1.7e-67 228.3 3.9 2.1e-50 172.1 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1183) PRNT PF15174.1 KOS17163.1 - 0.073 12.7 0.4 1.8 8.3 0.0 2.8 2 1 1 3 3 3 0 Prion-related protein testis-specific TMEM37 PF15108.1 KOS17164.1 - 0.0032 17.2 1.3 0.0038 16.9 0.9 1.1 1 0 0 1 1 1 1 Voltage-dependent calcium channel gamma-like subunit protein family YrvL PF14184.1 KOS17164.1 - 0.064 13.0 3.4 0.083 12.6 2.4 1.1 1 0 0 1 1 1 0 Regulatory protein YrvL SNF5 PF04855.7 KOS17165.1 - 3.5e-75 252.6 0.4 7.5e-75 251.5 0.1 1.6 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 TolB_N PF04052.8 KOS17165.1 - 0.13 12.3 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 TolB amino-terminal domain Peptidase_M24 PF00557.19 KOS17166.1 - 7.5e-11 41.9 0.0 1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 PUF PF00806.14 KOS17167.1 - 1.4e-27 93.5 0.0 5.7e-05 22.3 0.0 5.8 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 KOS17167.1 - 3.6e-13 48.9 0.0 6.8e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS17167.1 - 1.2e-06 28.2 0.0 2.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS17167.1 - 2.7e-06 27.2 0.0 1.4e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KOS17168.1 - 4.3e-59 199.7 0.2 1.8e-58 197.7 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17168.1 - 1.7e-43 148.6 0.1 6.3e-43 146.7 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KOS17168.1 - 1.7e-22 79.5 0.1 1.7e-22 79.5 0.0 3.0 3 0 0 3 3 3 1 P21-Rho-binding domain PH_11 PF15413.1 KOS17168.1 - 3.6e-08 33.6 0.0 1.1e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.1 KOS17168.1 - 0.00038 19.5 0.0 0.00076 18.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS17168.1 - 0.0088 15.8 0.7 0.044 13.5 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family PRP38_assoc PF12871.2 KOS17169.1 - 0.0015 18.9 43.7 0.0015 18.9 30.3 6.8 4 2 2 6 6 6 2 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Nop14 PF04147.7 KOS17169.1 - 0.0024 15.9 10.7 0.0024 15.9 7.4 3.3 3 1 0 4 4 4 1 Nop14-like family PHD PF00628.24 KOS17170.1 - 4.5e-16 58.2 20.1 1.1e-09 37.7 7.1 2.4 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.1 KOS17170.1 - 0.00098 18.8 16.2 0.026 14.2 1.6 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.1 KOS17170.1 - 0.018 15.2 8.5 0.5 10.5 2.9 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-PHD-like PF15446.1 KOS17170.1 - 0.082 12.1 8.3 1.4 8.2 2.1 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 KOS17170.1 - 0.13 12.0 17.4 0.25 11.0 0.8 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 KOS17170.1 - 3.4 7.0 20.1 0.16 11.3 3.9 3.5 4 0 0 4 4 4 0 PHD-finger Peptidase_M76 PF09768.4 KOS17171.1 - 6.3e-67 224.3 1.0 7.7e-67 224.0 0.7 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 KOS17171.1 - 0.0092 15.6 3.7 0.0092 15.6 2.6 2.1 1 1 0 2 2 2 1 SprT-like family Ribosomal_L40e PF01020.12 KOS17171.1 - 0.15 11.6 0.0 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 Ribosomal L40e family Pkinase PF00069.20 KOS17172.1 - 1.7e-70 237.1 0.0 2.2e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17172.1 - 3.2e-43 147.6 0.0 4.3e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS17172.1 - 9.7e-07 28.0 0.0 1.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KOS17172.1 - 0.00037 19.6 0.1 0.00058 18.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KOS17172.1 - 0.0099 15.2 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 KOS17172.1 - 0.031 13.6 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KOS17172.1 - 0.034 13.8 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family tRNA-synt_2b PF00587.20 KOS17173.1 - 1.1e-66 223.7 0.0 1.8e-66 222.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KOS17173.1 - 7.4e-23 80.3 1.2 7.4e-22 77.1 0.0 2.6 2 0 0 2 2 2 1 Anticodon binding domain AA_kinase PF00696.23 KOS17174.1 - 4.5e-40 137.7 0.7 5.8e-40 137.3 0.5 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KOS17174.1 - 1.3e-15 56.8 0.4 7.1e-15 54.4 0.0 2.2 2 0 0 2 2 2 1 PUA domain HEAT_2 PF13646.1 KOS17175.1 - 7.4e-07 29.3 2.7 0.00054 20.1 0.0 4.6 5 1 0 5 5 5 2 HEAT repeats HEAT PF02985.17 KOS17175.1 - 0.0012 18.7 1.4 0.3 11.2 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KOS17175.1 - 0.063 13.7 0.0 0.063 13.7 0.0 4.6 7 0 0 7 7 7 0 HEAT-like repeat CDC37_N PF03234.9 KOS17176.1 - 3.5e-54 183.7 0.3 3.5e-54 183.7 0.2 2.3 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KOS17176.1 - 3.6e-42 143.7 0.1 8.8e-42 142.5 0.1 1.7 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KOS17176.1 - 5e-23 80.8 5.4 5e-23 80.8 3.8 2.3 2 0 0 2 2 2 1 Cdc37 C terminal domain BAR PF03114.13 KOS17176.1 - 0.022 14.2 3.4 0.076 12.5 0.0 2.8 2 1 0 3 3 3 0 BAR domain hGDE_central PF14702.1 KOS17176.1 - 0.062 12.4 0.8 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 central domain of human glycogen debranching enzyme CCDC-167 PF15188.1 KOS17176.1 - 0.86 9.5 5.9 0.4 10.6 1.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Ribosomal_60s PF00428.14 KOS17176.1 - 1.5 9.2 28.9 0.037 14.4 4.6 3.9 3 1 0 3 3 3 0 60s Acidic ribosomal protein DUF3535 PF12054.3 KOS17177.1 - 6.6e-137 456.7 0.0 4.9e-136 453.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KOS17177.1 - 2.2e-74 249.9 0.0 3.4e-74 249.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS17177.1 - 1.6e-14 53.4 0.0 4e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 KOS17177.1 - 2.2e-14 52.1 6.4 0.024 14.6 0.0 8.6 10 0 0 10 10 10 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KOS17177.1 - 1.6e-05 25.1 0.3 0.28 11.5 0.0 4.0 2 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KOS17177.1 - 3.2e-05 24.2 1.0 44 4.7 0.0 6.9 6 0 0 6 6 6 0 HEAT-like repeat HEAT_2 PF13646.1 KOS17177.1 - 4.8e-05 23.5 6.1 0.091 13.0 0.0 6.2 6 2 1 7 7 7 1 HEAT repeats CLASP_N PF12348.3 KOS17177.1 - 0.01 15.1 0.6 0.39 10.0 0.1 3.5 3 2 0 3 3 3 0 CLASP N terminal Fungal_trans PF04082.13 KOS17178.1 - 2.6e-06 26.5 0.0 4.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C58 PF03543.9 KOS17178.1 - 0.015 14.8 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen GCV_H PF01597.14 KOS17180.1 - 1.3e-35 121.7 0.1 1.5e-35 121.5 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Ras PF00071.17 KOS17181.1 - 8.4e-32 109.7 0.2 1e-31 109.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS17181.1 - 5.9e-21 75.1 0.1 2.5e-20 73.1 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KOS17181.1 - 1.4e-06 27.6 0.1 1.9e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KOS17181.1 - 8.1e-05 21.8 0.2 0.00011 21.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KOS17181.1 - 0.054 12.1 0.2 0.14 10.8 0.0 1.8 1 1 1 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 KOS17181.1 - 0.057 13.3 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DLIC PF05783.6 KOS17181.1 - 0.097 11.3 0.1 5.8 5.4 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) PAPS_reduct PF01507.14 KOS17182.1 - 5.9e-29 101.1 0.0 1.5e-21 76.9 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family PLDc_2 PF13091.1 KOS17183.1 - 1.5e-14 53.8 0.0 6.7e-08 32.3 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KOS17183.1 - 8.6e-08 31.7 0.7 0.00079 19.1 0.1 2.9 2 1 0 2 2 2 2 Phospholipase D Active site motif DUF3306 PF11748.3 KOS17183.1 - 0.013 16.1 1.7 0.025 15.2 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) SPAN PF02510.9 KOS17183.1 - 3.1 6.7 11.9 5 6.0 8.3 1.2 1 0 0 1 1 1 0 Surface presentation of antigens protein NDUFA12 PF05071.11 KOS17184.1 - 2.2e-23 82.7 0.3 2.9e-23 82.3 0.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PNTB PF02233.11 KOS17185.1 - 4.1e-163 543.4 23.2 4.1e-163 543.4 16.1 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KOS17185.1 - 9.6e-55 184.6 0.6 2e-54 183.6 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KOS17185.1 - 5.9e-48 162.3 0.5 1.4e-47 161.1 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KOS17185.1 - 2.5e-31 107.6 3.8 2.5e-31 107.6 2.6 5.8 5 2 1 7 7 7 1 Domain of unknown function (DUF3814) ADH_zinc_N PF00107.21 KOS17185.1 - 0.00091 18.7 0.1 0.0035 16.8 0.1 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KOS17185.1 - 0.0051 15.9 1.9 0.34 10.0 0.0 2.9 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KOS17185.1 - 0.025 14.4 1.0 0.059 13.2 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fumerase PF05681.9 KOS17185.1 - 0.047 12.7 0.1 0.089 11.8 0.1 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) NAD_binding_8 PF13450.1 KOS17185.1 - 0.05 13.6 2.7 0.36 10.8 0.8 3.2 2 2 1 3 3 3 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KOS17185.1 - 0.05 12.4 0.8 0.1 11.4 0.6 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_18 PF12847.2 KOS17185.1 - 0.091 13.3 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KOS17185.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Tau95 PF09734.4 KOS17186.1 - 2.2e-63 214.4 0.0 2.8e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit TFIIA PF03153.8 KOS17186.1 - 0.58 9.9 16.7 1.1 9.1 11.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit B56 PF01603.15 KOS17187.1 - 3e-175 582.7 3.5 3.5e-175 582.5 2.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.2 KOS17187.1 - 0.0069 15.8 0.6 0.87 9.0 0.1 2.6 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal CTD_bind PF04818.8 KOS17188.1 - 1.3e-08 34.9 0.0 3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF936 PF06075.7 KOS17188.1 - 1.6 7.6 20.4 2.2 7.1 14.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Herpes_capsid PF06112.6 KOS17189.1 - 0.026 14.5 2.3 0.031 14.3 1.6 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein APC_CDC26 PF10471.4 KOS17189.1 - 0.37 11.5 3.1 0.54 11.0 2.2 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Exo_endo_phos PF03372.18 KOS17190.1 - 3.6e-28 99.1 0.6 5.3e-28 98.6 0.4 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 KOS17190.1 - 0.0036 17.1 0.4 0.041 13.7 0.0 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat CRAL_TRIO PF00650.15 KOS17191.1 - 2.6e-38 131.0 0.1 2.6e-38 131.0 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KOS17191.1 - 4e-07 30.0 0.1 4e-07 30.0 0.1 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KOS17191.1 - 0.0025 17.7 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain BCS1_N PF08740.6 KOS17192.1 - 6.3e-40 136.8 0.3 1e-39 136.1 0.2 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KOS17192.1 - 1.7e-17 63.8 0.0 2.9e-08 33.9 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KOS17192.1 - 0.00029 21.6 0.1 0.0011 19.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KOS17192.1 - 0.0098 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KOS17192.1 - 0.02 14.7 0.0 0.061 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KOS17192.1 - 0.026 13.9 0.0 0.066 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KOS17192.1 - 0.097 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.9 KOS17192.1 - 0.098 12.3 0.0 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TRAPP PF04051.11 KOS17193.1 - 1.5e-39 134.9 0.0 1.8e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Apc13p PF05839.6 KOS17194.1 - 6.6e-35 118.9 0.1 7.6e-35 118.7 0.1 1.0 1 0 0 1 1 1 1 Apc13p protein LRR_1 PF00560.28 KOS17195.1 - 9.1e-11 40.2 17.4 0.084 12.9 0.2 8.6 7 1 0 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.1 KOS17195.1 - 1.3e-10 40.1 14.6 0.14 12.3 0.0 8.5 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.2 KOS17195.1 - 2.6e-08 33.3 11.3 0.0094 15.5 0.0 6.5 5 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS17195.1 - 7.8e-07 28.7 11.2 0.077 12.7 0.0 5.5 4 1 3 7 7 7 4 Leucine rich repeat LRR_7 PF13504.1 KOS17195.1 - 0.0084 16.1 24.6 3.3 8.3 0.1 8.1 7 1 0 7 7 7 2 Leucine rich repeat His_Phos_1 PF00300.17 KOS17196.1 - 4e-23 82.2 0.0 4.8e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Tecti-min-caps PF09300.5 KOS17196.1 - 0.053 13.3 0.6 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Tectiviridae, minor capsid zf-RING_2 PF13639.1 KOS17197.1 - 0.2 11.4 10.6 0.26 11.1 5.1 2.7 2 1 0 2 2 2 0 Ring finger domain DEAD PF00270.24 KOS17198.1 - 3.8e-32 111.1 0.0 9.5e-32 109.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS17198.1 - 1e-17 63.7 0.0 2.1e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS17198.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 KOS17198.1 - 0.044 13.0 0.0 3.7 6.7 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain Helicase_C_2 PF13307.1 KOS17198.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain DUF1762 PF08574.5 KOS17199.1 - 7.4e-08 32.6 8.1 7.4e-08 32.6 5.6 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1762) SDA1 PF05285.7 KOS17199.1 - 0.0001 21.7 1.6 0.0001 21.7 1.1 1.7 1 1 0 1 1 1 1 SDA1 TIP41 PF04176.8 KOS17201.1 - 9.5e-67 223.7 5.1 8.8e-65 217.3 3.5 2.1 1 1 0 1 1 1 1 TIP41-like family BSP_II PF05432.6 KOS17201.1 - 0.00031 20.1 6.9 0.00048 19.4 4.8 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) VID27 PF08553.5 KOS17201.1 - 0.0072 14.6 0.4 0.0098 14.1 0.3 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein HhH-GPD PF00730.20 KOS17201.1 - 0.057 13.7 0.1 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein FAM176 PF14851.1 KOS17201.1 - 0.12 12.1 1.5 0.2 11.3 1.0 1.4 1 0 0 1 1 1 0 FAM176 family Ribosomal_60s PF00428.14 KOS17201.1 - 0.49 10.8 6.7 1.5 9.2 4.6 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Myc_N PF01056.13 KOS17201.1 - 0.57 9.3 4.9 0.84 8.7 3.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PBP1_TM PF14812.1 KOS17201.1 - 0.82 10.0 5.5 1.9 8.8 3.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mem_trans PF03547.13 KOS17202.1 - 0.028 12.7 0.1 0.045 12.0 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF572 PF04502.8 KOS17202.1 - 0.18 10.9 12.1 0.29 10.3 8.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Protocadherin PF08374.6 KOS17202.1 - 0.54 9.8 5.0 0.98 9.0 3.5 1.4 1 0 0 1 1 1 0 Protocadherin Pex26 PF07163.7 KOS17202.1 - 2.1 7.1 7.8 0.13 11.1 0.7 2.0 1 1 1 2 2 2 0 Pex26 protein Hid1 PF12722.2 KOS17202.1 - 5.7 4.4 8.2 8.2 3.9 5.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3635 PF12330.3 KOS17203.1 - 2.6e-06 27.4 0.1 4.2e-05 23.5 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) DUF77 PF01910.12 KOS17204.1 - 7.8e-32 108.8 0.1 8.8e-32 108.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Arm PF00514.18 KOS17205.1 - 6.6e-70 228.7 34.2 1.5e-13 50.0 0.1 11.0 11 0 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KOS17205.1 - 2.8e-23 82.0 13.2 2.2e-07 31.0 0.2 7.4 2 2 3 6 6 6 5 HEAT repeats HEAT PF02985.17 KOS17205.1 - 1.8e-18 64.8 16.8 0.016 15.2 0.0 9.5 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 KOS17205.1 - 5.6e-16 58.5 14.9 9e-05 22.8 0.2 8.2 6 3 3 9 9 9 6 HEAT-like repeat Adaptin_N PF01602.15 KOS17205.1 - 2.8e-11 42.4 9.5 4.6e-07 28.5 0.4 2.6 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 KOS17205.1 - 3.3e-11 42.7 8.7 0.00049 19.2 0.7 3.4 2 1 1 3 3 3 3 Armadillo-like KAP PF05804.7 KOS17205.1 - 1.2e-09 36.7 0.2 2.7e-09 35.5 0.1 1.5 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 KOS17205.1 - 5.4e-09 35.5 1.6 0.00046 19.4 0.3 3.6 2 1 1 3 3 3 2 V-ATPase subunit H DUF908 PF06012.7 KOS17205.1 - 0.00082 18.7 1.8 0.43 9.8 0.1 3.8 1 1 2 4 4 4 1 Domain of Unknown Function (DUF908) DUF2454 PF10521.4 KOS17205.1 - 0.0036 16.3 0.5 0.009 15.0 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) Vac14_Fab1_bd PF12755.2 KOS17205.1 - 0.019 15.3 0.2 3.1 8.2 0.0 3.5 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 KOS17205.1 - 0.029 14.8 9.2 28 5.5 0.1 7.0 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat DUF1981 PF09324.5 KOS17205.1 - 0.14 11.7 0.0 5.4 6.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) Peptidase_S26 PF10502.4 KOS17206.1 - 5.5e-06 25.9 0.0 0.00029 20.3 0.0 2.6 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 KOS17206.1 - 5.2e-05 22.8 0.0 8.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like adh_short_C2 PF13561.1 KOS17207.1 - 9.6e-30 104.1 0.1 1.2e-29 103.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KOS17207.1 - 4.7e-26 91.6 0.9 5.6e-26 91.4 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS17207.1 - 5.4e-11 42.4 0.7 1.9e-10 40.6 0.5 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KOS17207.1 - 2.8e-07 30.2 0.1 5e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KOS17207.1 - 0.00062 19.8 1.6 0.0014 18.6 1.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KOS17207.1 - 0.0033 16.6 0.0 0.0049 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KOS17207.1 - 0.09 12.5 0.7 3.3 7.5 0.2 2.6 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HAD PF12710.2 KOS17207.1 - 0.096 12.8 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase AdoHcyase_NAD PF00670.16 KOS17207.1 - 0.11 12.3 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain LSM PF01423.17 KOS17208.1 - 1.2e-16 59.9 0.0 1.6e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L4 PF00573.17 KOS17209.1 - 1.5e-43 148.4 0.0 2e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.15 KOS17210.1 - 5.8e-11 42.4 0.0 1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Rep_fac-A_3 PF08661.6 KOS17211.1 - 3e-12 46.4 0.1 4.3e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Replication factor A protein 3 CENP-K PF11802.3 KOS17212.1 - 0.043 13.0 1.2 0.06 12.5 0.8 1.1 1 0 0 1 1 1 0 Centromere-associated protein K ADIP PF11559.3 KOS17212.1 - 0.078 12.8 3.4 0.2 11.5 1.5 2.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KOS17212.1 - 0.12 11.9 1.8 0.16 11.5 1.2 1.2 1 0 0 1 1 1 0 IncA protein Tropomyosin PF00261.15 KOS17212.1 - 0.13 11.3 4.4 0.18 10.8 3.1 1.1 1 0 0 1 1 1 0 Tropomyosin Tropomyosin_1 PF12718.2 KOS17212.1 - 0.66 9.8 5.4 2.3 8.0 3.8 1.7 1 1 0 1 1 1 0 Tropomyosin like CorA PF01544.13 KOS17213.1 - 4.9e-10 38.9 7.1 4.1e-09 35.8 2.9 2.3 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein DUF676 PF05057.9 KOS17214.1 - 9.2e-06 25.1 0.0 1.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) CDC45 PF02724.9 KOS17214.1 - 0.0046 15.0 3.4 0.93 7.4 0.0 2.1 2 0 0 2 2 2 2 CDC45-like protein PGAP1 PF07819.8 KOS17214.1 - 0.023 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 KOS17214.1 - 0.097 12.5 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ribonucleas_3_3 PF14622.1 KOS17215.1 - 1.1e-21 77.0 0.0 2.3e-21 76.0 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Mucin PF01456.12 KOS17215.1 - 0.39 10.4 10.6 0.58 9.9 7.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2076 PF09849.4 KOS17217.1 - 0.0069 16.4 0.3 0.0073 16.3 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Tetraspannin PF00335.15 KOS17217.1 - 0.019 14.2 0.1 0.02 14.1 0.0 1.0 1 0 0 1 1 1 0 Tetraspanin family Baculo_VP91_N PF08475.5 KOS17217.1 - 0.14 11.4 0.2 0.17 11.2 0.2 1.1 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal IPP-2 PF04979.9 KOS17218.1 - 1.2e-08 35.2 7.7 2.8e-05 24.3 0.4 2.4 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) Cupin_2 PF07883.6 KOS17219.1 - 0.037 13.5 0.0 0.099 12.1 0.0 1.7 1 0 0 1 1 1 0 Cupin domain MTH865 PF07747.6 KOS17219.1 - 0.058 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 MTH865-like family Cupin_3 PF05899.7 KOS17219.1 - 0.085 12.2 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Ribosomal_L27 PF01016.14 KOS17220.1 - 3.9e-23 81.0 0.1 3.9e-23 81.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal L27 protein Cutinase PF01083.17 KOS17221.1 - 9.6e-48 162.2 3.8 1.2e-47 161.9 2.6 1.1 1 0 0 1 1 1 1 Cutinase Thioesterase PF00975.15 KOS17221.1 - 9.1e-05 22.7 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.6 KOS17221.1 - 0.00014 21.3 0.1 0.00021 20.7 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 KOS17221.1 - 0.0012 18.5 0.2 0.0018 18.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS17221.1 - 0.0032 17.0 0.1 0.0045 16.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KOS17221.1 - 0.005 16.3 0.0 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_9 PF10081.4 KOS17221.1 - 0.0068 15.1 0.0 0.0091 14.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta-hydrolase family VirJ PF06057.6 KOS17221.1 - 0.0092 15.7 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PGAP1 PF07819.8 KOS17221.1 - 0.01 15.4 0.1 0.014 14.9 0.1 1.1 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 KOS17221.1 - 0.013 15.4 0.2 0.017 14.9 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 KOS17221.1 - 0.025 14.1 0.1 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 KOS17221.1 - 0.035 13.4 0.1 0.054 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3739 PF12545.3 KOS17221.1 - 0.06 13.4 0.9 0.097 12.7 0.0 1.8 2 0 0 2 2 2 0 Filamentous haemagglutinin family outer membrane protein KAT11 PF08214.6 KOS17222.1 - 1.3e-81 274.4 0.0 2.3e-81 273.5 0.0 1.4 1 1 0 1 1 1 1 Histone acetylation protein Roughex PF06020.6 KOS17222.1 - 0.072 11.7 4.3 0.11 11.1 0.4 2.5 3 0 0 3 3 3 0 Drosophila roughex protein JmjC PF02373.17 KOS17223.1 - 2.9e-43 146.7 0.3 6.8e-43 145.5 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PLU-1 PF08429.6 KOS17223.1 - 1e-39 136.3 11.4 1.2e-14 53.9 2.2 4.1 1 1 2 3 3 3 3 PLU-1-like protein zf-C5HC2 PF02928.11 KOS17223.1 - 5.1e-10 39.2 0.7 1.1e-09 38.2 0.5 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger GIY-YIG PF01541.19 KOS17224.1 - 2.4e-07 31.0 0.0 4.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain Ribosomal_60s PF00428.14 KOS17224.1 - 0.2 12.1 7.6 0.38 11.1 5.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein bZIP_1 PF00170.16 KOS17225.1 - 0.046 13.6 5.7 0.077 12.9 3.7 1.6 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 KOS17225.1 - 1.5 8.7 12.4 0.12 12.1 2.8 2.5 3 0 0 3 3 3 0 Basic region leucine zipper tRNA-synt_1c PF00749.16 KOS17226.1 - 2.2e-101 338.6 0.1 2.8e-101 338.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KOS17226.1 - 2.8e-37 128.0 0.0 4.2e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 KOS17226.1 - 0.039 13.0 0.2 0.12 11.4 0.0 1.5 1 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain SurE PF01975.12 KOS17227.1 - 6.4e-28 97.4 0.0 9.4e-28 96.8 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Alb1 PF09135.6 KOS17228.1 - 5.6e-20 72.0 11.0 1.2e-19 70.9 7.6 1.5 1 1 0 1 1 1 1 Alb1 DivIVA PF05103.8 KOS17228.1 - 0.023 14.7 0.4 0.038 14.0 0.2 1.4 1 1 0 1 1 1 0 DivIVA protein DUF4650 PF15509.1 KOS17228.1 - 0.024 13.6 0.5 0.028 13.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4650) Nucleoplasmin PF03066.10 KOS17228.1 - 0.047 13.2 1.4 0.061 12.8 1.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin RNA_pol_3_Rpc31 PF11705.3 KOS17228.1 - 0.076 12.9 4.8 0.11 12.4 3.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.6 KOS17228.1 - 0.29 10.9 3.4 0.42 10.4 2.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal ANAPC15 PF15243.1 KOS17228.1 - 0.73 9.9 6.6 1.4 8.9 4.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF4611 PF15387.1 KOS17228.1 - 2.2 8.4 8.1 5.6 7.1 5.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.5 KOS17228.1 - 4.4 7.6 9.0 7.2 6.9 6.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain E1-E2_ATPase PF00122.15 KOS17229.1 - 2.2e-51 174.1 1.5 3.5e-51 173.4 0.4 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KOS17229.1 - 5.8e-39 134.7 3.4 3.7e-38 132.0 2.2 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KOS17229.1 - 9.4e-17 61.8 0.0 2.9e-16 60.1 0.0 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KOS17229.1 - 1.7e-07 31.1 0.1 2.2e-05 24.2 0.1 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KOS17229.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase FAD_binding_1 PF00667.15 KOS17230.1 - 1.1e-57 194.9 0.0 1.8e-57 194.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KOS17230.1 - 7.3e-12 45.8 0.0 1.7e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Transketolase_C PF02780.15 KOS17230.1 - 0.00099 19.0 0.1 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain POR PF01558.13 KOS17230.1 - 0.021 14.7 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase zf-Nse PF11789.3 KOS17231.1 - 5.5e-23 80.2 0.7 9.2e-23 79.5 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 KOS17231.1 - 0.00079 18.8 0.5 0.0013 18.1 0.3 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 KOS17231.1 - 0.0035 17.0 0.6 0.0084 15.8 0.3 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 KOS17231.1 - 0.024 14.4 0.3 0.04 13.7 0.2 1.4 1 0 0 1 1 1 0 Ring finger domain DUF3245 PF11595.3 KOS17231.1 - 0.042 14.1 2.1 0.042 14.1 1.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) Atg14 PF10186.4 KOS17231.1 - 0.075 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Rtf2 PF04641.7 KOS17231.1 - 0.076 12.1 0.5 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 Rtf2 RING-finger zf-rbx1 PF12678.2 KOS17231.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 RING-H2 zinc finger RXT2_N PF08595.6 KOS17231.1 - 1.3 8.7 8.8 0.71 9.6 0.4 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal PAS_9 PF13426.1 KOS17232.1 - 7e-13 48.8 0.0 1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 KOS17232.1 - 0.0014 18.3 0.0 0.0026 17.5 0.0 1.6 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.1 KOS17232.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.6 KOS17232.1 - 0.061 13.4 0.0 2.9 8.0 0.0 2.1 2 0 0 2 2 2 0 PAS fold Pkinase PF00069.20 KOS17233.1 - 6.9e-73 244.9 0.0 8.3e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17233.1 - 2.5e-32 112.0 0.0 3e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS17233.1 - 0.00085 18.3 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KOS17233.1 - 0.0042 15.9 0.0 0.0063 15.3 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KOS17233.1 - 0.0052 16.5 0.0 0.011 15.4 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KOS17233.1 - 0.027 13.5 0.1 0.092 11.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KOS17233.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DSBA PF01323.15 KOS17234.1 - 4.1e-15 55.8 0.0 1.4e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 DSBA-like thioredoxin domain CobT PF06213.7 KOS17234.1 - 0.002 17.3 0.6 0.0027 16.8 0.4 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT CENP-B_dimeris PF09026.5 KOS17234.1 - 0.0037 17.4 7.4 0.0079 16.4 5.1 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Ribosomal_60s PF00428.14 KOS17234.1 - 0.0067 16.7 1.8 0.013 15.8 1.2 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sigma70_ner PF04546.8 KOS17234.1 - 0.17 11.4 5.2 0.32 10.5 3.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 KOS17234.1 - 0.32 10.8 1.9 0.47 10.2 1.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.1 KOS17234.1 - 0.42 10.2 3.0 0.67 9.6 2.0 1.3 1 0 0 1 1 1 0 FAM176 family Daxx PF03344.10 KOS17234.1 - 2.6 6.4 7.4 3.5 6.0 5.1 1.1 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 KOS17234.1 - 6.6 6.2 13.7 11 5.5 9.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 KOS17234.1 - 10 5.3 9.8 15 4.7 6.8 1.1 1 0 0 1 1 1 0 NOA36 protein Cyclin_N PF00134.18 KOS17235.1 - 1.4e-13 50.5 0.0 3e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KOS17235.1 - 1.6e-09 38.3 0.0 4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Cyclin DHBP_synthase PF00926.14 KOS17236.1 - 6.7e-73 244.0 0.0 2e-72 242.4 0.0 1.6 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Methyltransf_23 PF13489.1 KOS17237.1 - 8.7e-21 74.3 0.0 1.3e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS17237.1 - 6.6e-18 65.0 0.0 1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS17237.1 - 7.8e-17 61.5 0.0 1.2e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS17237.1 - 1.9e-16 59.9 0.0 2.6e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS17237.1 - 1.2e-15 58.0 0.0 2e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS17237.1 - 1.3e-08 34.8 0.0 4.8e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS17237.1 - 1.1e-06 28.8 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KOS17237.1 - 7.8e-05 21.9 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KOS17237.1 - 0.0022 17.3 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 KOS17237.1 - 0.0025 16.5 0.0 0.0038 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 KOS17237.1 - 0.0044 16.1 0.0 0.006 15.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KOS17237.1 - 0.0069 15.5 0.0 0.0097 15.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 KOS17237.1 - 0.021 14.2 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.7 KOS17237.1 - 0.2 10.4 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase UPF0029 PF01205.14 KOS17238.1 - 2.7e-23 81.7 0.0 5.8e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 HhH-GPD PF00730.20 KOS17238.1 - 0.2 11.9 1.0 0.39 11.0 0.7 1.7 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein MBOAT PF03062.14 KOS17239.1 - 9.8e-29 100.4 20.9 3.3e-28 98.7 10.7 2.7 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family DUF2414 PF10309.4 KOS17240.1 - 1.1e-19 69.7 0.0 2e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 KOS17240.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain MIP-T3 PF10243.4 KOS17240.1 - 2 6.8 22.8 2.9 6.2 15.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DNA_pol_lambd_f PF10391.4 KOS17241.1 - 3.9e-19 67.9 0.4 7.7e-19 66.9 0.3 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 KOS17241.1 - 1e-18 66.7 0.0 2.4e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 KOS17241.1 - 1.8e-15 56.9 0.0 3.7e-15 55.9 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 KOS17241.1 - 8.2e-12 45.1 0.1 3e-11 43.3 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 KOS17241.1 - 0.015 15.6 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH_5 PF14520.1 KOS17241.1 - 0.066 13.3 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF4462 PF14692.1 KOS17241.1 - 0.08 12.2 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Herpes_LMP2 PF07415.6 KOS17241.1 - 1.2 7.5 2.3 1.8 7.0 1.6 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein TFIIE_alpha PF02002.12 KOS17242.1 - 1.7e-08 33.8 0.1 4.1e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit DUF2024 PF09630.5 KOS17242.1 - 0.055 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) DUF3391 PF11871.3 KOS17242.1 - 0.21 11.8 0.1 0.21 11.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Voldacs PF03517.8 KOS17242.1 - 4.5 7.1 7.9 0.4 10.5 0.3 2.2 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling HEAT_EZ PF13513.1 KOS17243.1 - 9.2e-27 92.8 12.9 3.7e-14 52.6 0.1 10.5 10 1 2 12 12 12 3 HEAT-like repeat HEAT PF02985.17 KOS17243.1 - 7.5e-25 84.7 7.0 0.0002 21.1 0.0 9.6 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.1 KOS17243.1 - 3.1e-20 72.2 4.0 3.8e-08 33.5 0.0 7.7 4 3 4 8 8 8 4 HEAT repeats Vac14_Fab1_bd PF12755.2 KOS17243.1 - 1.3e-08 35.1 0.0 0.0047 17.2 0.0 5.1 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KOS17243.1 - 2.1e-07 30.9 0.1 1.1 9.0 0.0 5.6 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 KOS17243.1 - 3.4e-06 26.0 0.1 0.12 11.1 0.0 4.5 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal Arm PF00514.18 KOS17243.1 - 7.3e-06 25.6 2.5 0.04 13.7 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 KOS17243.1 - 1.5e-05 24.8 0.4 0.00059 19.7 0.1 3.8 3 1 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 KOS17243.1 - 0.001 18.4 0.0 12 5.1 0.0 5.3 5 2 0 6 6 6 0 CLASP N terminal GCIP PF13324.1 KOS17243.1 - 0.0099 15.1 0.6 3.1 6.9 0.0 2.5 2 0 0 2 2 2 2 Grap2 and cyclin-D-interacting HEAT_PBS PF03130.11 KOS17243.1 - 0.056 13.9 2.5 1 9.9 0.0 4.3 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat DUF3437 PF11919.3 KOS17243.1 - 0.16 11.7 0.0 2.2 8.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) CENP-T PF15511.1 KOS17243.1 - 0.7 9.0 5.6 1.1 8.4 3.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 KOS17243.1 - 0.74 7.7 1.8 1.1 7.2 1.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Fungal_trans_2 PF11951.3 KOS17244.1 - 6.2e-08 31.6 0.9 8.9e-08 31.1 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNARE PF05739.14 KOS17245.1 - 8.5e-19 67.0 8.0 1.7e-18 66.0 2.8 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KOS17245.1 - 2.1e-12 47.0 5.2 1.2e-11 44.7 0.1 2.4 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 KOS17245.1 - 0.11 12.0 10.4 0.16 11.5 0.8 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LRR19-TM PF15176.1 KOS17245.1 - 0.2 11.3 1.0 0.68 9.6 0.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain HAUS-augmin3 PF14932.1 KOS17245.1 - 0.78 8.8 7.6 0.1 11.7 0.3 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 SlyX PF04102.7 KOS17245.1 - 0.82 10.0 10.6 5 7.5 0.8 3.5 2 1 1 3 3 3 0 SlyX Syntaxin_2 PF14523.1 KOS17245.1 - 4.8 7.2 13.4 7.1 6.7 3.5 3.1 2 1 1 3 3 3 0 Syntaxin-like protein EF-hand_1 PF00036.27 KOS17246.1 - 1.4e-39 130.3 12.1 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KOS17246.1 - 1.9e-34 117.6 4.6 1.3e-18 66.8 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KOS17246.1 - 1.4e-32 111.0 12.0 2.5e-15 55.8 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KOS17246.1 - 3.4e-29 98.0 7.2 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KOS17246.1 - 6.1e-25 85.4 9.2 1.4e-06 27.3 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KOS17246.1 - 1.8e-14 53.3 0.2 1.3e-07 31.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KOS17246.1 - 8.1e-09 35.1 1.9 0.001 18.7 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 KOS17246.1 - 9e-08 31.6 0.1 0.042 13.4 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 KOS17246.1 - 9.7e-08 32.0 0.1 0.0088 16.0 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 KOS17246.1 - 1.2e-06 28.4 2.0 8.9e-06 25.5 0.2 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 KOS17246.1 - 0.00031 20.4 0.3 0.2 11.3 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 KOS17246.1 - 0.00052 19.6 0.2 0.059 12.9 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein Toprim_2 PF13155.1 KOS17246.1 - 0.0094 16.2 1.0 2.4 8.5 0.0 2.4 1 1 1 2 2 2 1 Toprim-like RNA_pol_Rpb4 PF03874.11 KOS17246.1 - 0.013 15.4 0.7 3.9 7.4 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb4 Tenui_NCP PF04876.7 KOS17246.1 - 0.017 14.6 0.1 1.1 8.7 0.0 2.2 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein DUF3349 PF11829.3 KOS17246.1 - 0.019 15.3 0.3 8.6 6.8 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) DUF1103 PF06513.6 KOS17246.1 - 0.11 11.9 1.3 0.13 11.5 0.9 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) RloB PF13707.1 KOS17246.1 - 0.38 10.3 3.9 1.1 8.9 1.0 2.2 1 1 1 2 2 2 0 RloB-like protein EF-hand_10 PF14788.1 KOS17246.1 - 0.8 9.4 3.3 1.9 8.2 0.1 3.0 2 1 1 3 3 3 0 EF hand TATR PF03430.8 KOS17247.1 - 1.2 7.7 2.1 1.4 7.4 1.5 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator FAM165 PF14981.1 KOS17247.1 - 5.2 6.6 9.9 0.33 10.4 1.9 2.6 2 0 0 2 2 2 0 FAM165 family Exo_endo_phos PF03372.18 KOS17248.1 - 1.8e-11 44.4 0.7 2.4e-11 44.0 0.5 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KOS17248.1 - 0.083 12.5 0.0 0.25 10.9 0.0 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase F-box PF00646.28 KOS17250.1 - 0.0034 16.9 1.4 0.0058 16.2 0.1 2.2 2 0 0 2 2 2 1 F-box domain DUF3455 PF11937.3 KOS17251.1 - 9.8e-40 136.3 0.2 1.2e-39 136.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Reovirus_M2 PF05993.7 KOS17251.1 - 0.25 9.1 1.9 0.67 7.7 0.1 1.9 2 0 0 2 2 2 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) CASP_C PF08172.7 KOS17252.1 - 5.8e-89 297.3 0.1 5.8e-89 297.3 0.1 3.6 2 1 1 3 3 3 1 CASP C terminal DUF4164 PF13747.1 KOS17252.1 - 0.023 14.8 1.0 0.023 14.8 0.7 5.8 5 2 1 6 6 6 0 Domain of unknown function (DUF4164) Rad9 PF04139.8 KOS17252.1 - 0.028 13.5 1.8 0.048 12.7 1.3 1.4 1 0 0 1 1 1 0 Rad9 CENP-F_leu_zip PF10473.4 KOS17252.1 - 8.3 6.2 63.9 0.52 10.1 3.7 5.8 4 1 1 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps39_2 PF10367.4 KOS17254.1 - 0.00069 19.7 0.0 0.0023 18.0 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KOS17254.1 - 0.0017 18.3 0.2 0.053 13.5 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 KOS17254.1 - 0.0099 15.4 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 1 Region in Clathrin and VPS Methyltransf_16 PF10294.4 KOS17255.1 - 1.5e-05 24.5 0.0 0.0054 16.2 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase zf-C2H2_4 PF13894.1 KOS17256.1 - 4e-05 23.6 14.2 0.078 13.3 0.0 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KOS17256.1 - 0.00021 21.4 20.2 0.97 9.9 0.0 4.7 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KOS17256.1 - 0.0027 17.5 1.2 0.044 13.7 0.7 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger OSTMP1 PF09777.4 KOS17256.1 - 0.013 14.6 0.1 0.024 13.8 0.1 1.4 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF629 PF04780.7 KOS17256.1 - 0.019 13.4 0.5 0.23 9.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 KOS17256.1 - 0.028 14.5 0.1 0.028 14.5 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF230 PF03003.11 KOS17256.1 - 0.07 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Poxvirus proteins of unknown function zf-H2C2_5 PF13909.1 KOS17256.1 - 4.8 7.6 7.0 29 5.1 0.9 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Fibrillarin PF01269.12 KOS17258.1 - 3.4e-102 340.2 0.0 4e-102 339.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KOS17258.1 - 7.3e-06 25.6 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ribosomal_L22 PF00237.14 KOS17259.1 - 8.7e-34 115.6 0.1 1.2e-33 115.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Elf1 PF05129.8 KOS17260.1 - 1.4e-28 98.3 0.2 1.7e-28 98.0 0.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Cys_rich_CPXG PF14255.1 KOS17260.1 - 0.029 14.1 0.6 0.042 13.6 0.4 1.3 1 0 0 1 1 1 0 Cysteine-rich CPXCG PEMT PF04191.8 KOS17261.1 - 2.7e-28 98.1 0.9 4.4e-28 97.4 0.6 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase DNA_primase_lrg PF04104.9 KOS17262.1 - 4.3e-76 255.6 0.0 5.6e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Pkinase PF00069.20 KOS17263.1 - 2.1e-49 168.0 0.0 5e-49 166.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17263.1 - 4.7e-28 97.9 0.0 6.8e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS17263.1 - 0.0066 15.4 0.0 0.024 13.6 0.0 1.8 1 1 0 1 1 1 1 Kinase-like GCD14 PF08704.5 KOS17264.1 - 0.043 13.2 0.0 6.1 6.2 0.0 2.2 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 KOS17264.1 - 3.4 7.7 6.4 13 5.8 4.4 2.1 1 1 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.19 KOS17267.1 - 2e-90 303.5 22.1 2.5e-90 303.2 15.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS17267.1 - 3.7e-11 42.3 42.0 6.4e-09 34.9 22.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UAA PF08449.6 KOS17267.1 - 0.0018 17.2 0.4 0.0042 16.0 0.3 1.6 1 0 0 1 1 1 1 UAA transporter family DUF2956 PF11169.3 KOS17268.1 - 0.016 15.1 9.2 0.02 14.8 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Spore_coat_CotO PF14153.1 KOS17268.1 - 0.03 13.7 21.7 0.033 13.6 15.1 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Dynamin_N PF00350.18 KOS17268.1 - 0.046 13.5 5.1 0.057 13.2 3.5 1.1 1 0 0 1 1 1 0 Dynamin family FYDLN_acid PF09538.5 KOS17268.1 - 0.061 13.9 15.1 0.071 13.6 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF1510 PF07423.6 KOS17268.1 - 0.096 12.0 25.3 0.11 11.8 17.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 KOS17268.1 - 0.12 11.3 6.3 0.13 11.1 4.4 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.5 KOS17268.1 - 0.16 11.0 19.2 0.17 10.9 13.3 1.0 1 0 0 1 1 1 0 BUD22 DUF2052 PF09747.4 KOS17268.1 - 0.16 11.8 22.8 0.19 11.6 15.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF3449 PF11931.3 KOS17268.1 - 0.22 10.9 12.6 0.25 10.8 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF1266 PF06889.6 KOS17268.1 - 0.33 10.7 8.8 0.41 10.4 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DUF3306 PF11748.3 KOS17268.1 - 0.34 11.5 15.2 0.39 11.3 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Plasmodium_Vir PF05795.6 KOS17268.1 - 0.34 10.0 7.5 0.35 10.0 5.2 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2722 PF10846.3 KOS17268.1 - 0.38 9.7 8.6 0.4 9.6 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SDA1 PF05285.7 KOS17268.1 - 0.39 9.9 23.5 0.4 9.9 16.3 1.0 1 0 0 1 1 1 0 SDA1 NARP1 PF12569.3 KOS17268.1 - 0.65 8.6 16.8 0.69 8.6 11.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4628 PF15429.1 KOS17268.1 - 0.67 9.3 12.6 0.72 9.2 8.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) DUF2413 PF10310.4 KOS17268.1 - 0.79 8.4 17.8 0.85 8.3 12.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) U79_P34 PF03064.11 KOS17268.1 - 0.81 9.1 11.9 0.78 9.2 8.2 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FLO_LFY PF01698.11 KOS17268.1 - 1 8.1 13.3 1.1 8.0 9.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein SpoIIP PF07454.6 KOS17268.1 - 1.1 8.4 12.7 1.2 8.2 8.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) ATP-synt_E PF05680.7 KOS17268.1 - 1.5 8.8 15.7 2.4 8.1 10.9 1.4 1 0 0 1 1 1 0 ATP synthase E chain SpoIIIAH PF12685.2 KOS17268.1 - 1.7 8.0 14.7 1.9 7.9 10.2 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein Peptidase_U57 PF05582.7 KOS17268.1 - 1.9 7.3 6.8 2 7.3 4.7 1.0 1 0 0 1 1 1 0 YabG peptidase U57 YqfQ PF14181.1 KOS17268.1 - 2 8.4 21.0 2.4 8.1 14.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein CENP-T PF15511.1 KOS17268.1 - 2.2 7.4 17.4 2.1 7.4 12.1 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF3513 PF12026.3 KOS17268.1 - 2.4 7.6 13.3 2.7 7.5 9.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) RP-C_C PF11800.3 KOS17268.1 - 2.7 7.6 11.6 3 7.4 8.0 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Bul1_N PF04425.7 KOS17268.1 - 2.9 6.3 6.7 3.1 6.2 4.6 1.0 1 0 0 1 1 1 0 Bul1 N terminus Raftlin PF15250.1 KOS17268.1 - 3.4 6.0 12.6 3.7 5.9 8.7 1.0 1 0 0 1 1 1 0 Raftlin SelP_N PF04592.9 KOS17268.1 - 3.8 6.8 8.9 4.2 6.6 6.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Rtf2 PF04641.7 KOS17268.1 - 4 6.5 13.4 4.7 6.3 9.3 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4175 PF13779.1 KOS17268.1 - 4.7 4.7 23.1 5.3 4.6 16.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF1448 PF07289.6 KOS17268.1 - 4.7 6.0 7.2 5.1 5.9 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) Daxx PF03344.10 KOS17268.1 - 4.8 5.5 32.0 5 5.4 22.2 1.0 1 0 0 1 1 1 0 Daxx Family DUF4045 PF13254.1 KOS17268.1 - 5.1 6.2 13.1 5.5 6.1 9.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DHHW PF14286.1 KOS17268.1 - 5.2 6.2 12.3 5.8 6.1 8.5 1.0 1 0 0 1 1 1 0 DHHW protein DDHD PF02862.12 KOS17268.1 - 5.4 6.7 17.2 6.4 6.5 11.9 1.0 1 0 0 1 1 1 0 DDHD domain BORG_CEP PF14957.1 KOS17268.1 - 5.5 7.9 10.6 6.8 7.6 7.3 1.1 1 0 0 1 1 1 0 Cdc42 effector EIIBC-GUT_N PF03612.9 KOS17268.1 - 5.5 6.5 8.3 6.9 6.2 5.7 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Gti1_Pac2 PF09729.4 KOS17268.1 - 5.7 6.7 8.5 6.7 6.5 5.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Gag_spuma PF03276.9 KOS17268.1 - 5.9 5.1 12.6 6.5 4.9 8.7 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Bud13 PF09736.4 KOS17268.1 - 6 7.1 22.6 7.6 6.7 15.7 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex RRN3 PF05327.6 KOS17268.1 - 6.2 4.7 15.9 6.5 4.7 11.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.9 KOS17268.1 - 6.4 6.2 20.4 8.1 5.9 14.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein eIF3_subunit PF08597.5 KOS17268.1 - 6.5 6.2 24.3 7.4 6.0 16.8 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Cellulose_synt PF03552.9 KOS17268.1 - 6.8 4.8 8.0 7.7 4.6 5.5 1.1 1 0 0 1 1 1 0 Cellulose synthase Nop14 PF04147.7 KOS17268.1 - 7.9 4.2 28.6 8.4 4.1 19.8 1.0 1 0 0 1 1 1 0 Nop14-like family GAGA_bind PF06217.7 KOS17268.1 - 8.3 6.2 10.5 9.7 6.0 7.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Trypan_glycop_C PF10659.4 KOS17268.1 - 8.7 6.7 17.1 11 6.3 11.9 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain IncA PF04156.9 KOS17268.1 - 9.5 5.7 19.4 10 5.6 13.4 1.0 1 0 0 1 1 1 0 IncA protein PAS PF00989.19 KOS17270.1 - 0.0029 17.3 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold MFS_1 PF07690.11 KOS17271.1 - 1.1e-34 119.6 41.7 1.1e-34 119.6 28.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS17271.1 - 2.7e-07 29.5 26.2 2.4e-06 26.4 18.3 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_M35 PF02102.10 KOS17272.1 - 8.1e-58 195.7 10.5 3.7e-56 190.3 7.3 2.0 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 KOS17272.1 - 0.00085 19.8 2.6 0.0067 16.9 0.2 2.5 2 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase LRR_4 PF12799.2 KOS17273.1 - 4.9e-40 134.5 30.7 4e-08 32.7 0.9 9.5 6 2 3 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS17273.1 - 2.6e-37 126.3 29.5 1.4e-07 31.1 2.2 7.7 5 2 5 10 10 10 8 Leucine rich repeat LRR_1 PF00560.28 KOS17273.1 - 1.1e-22 76.4 31.6 0.15 12.2 0.1 15.3 15 2 0 15 15 15 7 Leucine Rich Repeat LRR_6 PF13516.1 KOS17273.1 - 2.3e-15 54.8 19.6 0.065 13.3 1.0 12.0 12 0 0 12 12 12 4 Leucine Rich repeat LRR_7 PF13504.1 KOS17273.1 - 1.7e-10 39.3 33.2 7.4 7.2 0.0 14.3 15 0 0 15 15 15 3 Leucine rich repeat LRR_9 PF14580.1 KOS17273.1 - 1.5e-05 24.5 11.2 0.11 12.0 0.0 5.2 2 2 3 5 5 5 3 Leucine-rich repeat MRP-L27 PF09809.4 KOS17274.1 - 1e-16 60.5 0.1 1.4e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 zf-RING_2 PF13639.1 KOS17275.1 - 3.7e-10 39.4 5.7 5.7e-10 38.8 4.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KOS17275.1 - 7.9e-09 35.5 0.6 1.3e-08 34.8 0.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KOS17275.1 - 2.9e-05 23.8 3.0 6.2e-05 22.7 2.1 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KOS17275.1 - 0.0024 17.5 4.3 0.0041 16.7 3.0 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NMD3 PF04981.8 KOS17275.1 - 0.0075 15.4 0.1 0.011 14.8 0.1 1.2 1 0 0 1 1 1 1 NMD3 family zf-C3HC4 PF00097.20 KOS17275.1 - 0.053 13.1 4.3 0.087 12.4 3.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS17275.1 - 0.08 12.9 6.6 0.14 12.2 4.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KOS17275.1 - 0.12 12.0 2.4 0.15 11.6 0.3 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 KOS17275.1 - 0.25 11.1 3.4 0.49 10.1 2.4 1.5 1 1 0 1 1 1 0 zinc-RING finger domain NAD_binding_10 PF13460.1 KOS17276.1 - 4.7e-13 49.5 3.5 6.1e-13 49.1 2.4 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KOS17276.1 - 3.6e-09 36.3 0.1 6.3e-09 35.6 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KOS17276.1 - 5.7e-08 32.2 0.3 7.7e-08 31.8 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KOS17276.1 - 0.0014 17.3 0.0 0.0035 16.0 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KOS17276.1 - 0.0063 15.4 0.0 0.22 10.4 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein DUF1471 PF07338.8 KOS17276.1 - 0.085 12.5 0.4 0.32 10.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1471) Semialdhyde_dh PF01118.19 KOS17276.1 - 0.1 12.9 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HIM1 PF08732.5 KOS17276.1 - 0.17 10.2 0.0 0.38 9.1 0.0 1.4 1 1 0 1 1 1 0 HIM1 Flavokinase PF01687.12 KOS17277.1 - 3.7e-36 123.7 0.0 4.3e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Spt20 PF12090.3 KOS17278.1 - 0.0019 17.5 5.0 0.0031 16.8 3.5 1.3 1 0 0 1 1 1 1 Spt20 family Fimbrial_K88 PF02432.10 KOS17278.1 - 0.065 12.6 0.5 0.12 11.7 0.4 1.4 1 0 0 1 1 1 0 Fimbrial, major and minor subunit AAA_23 PF13476.1 KOS17278.1 - 3.2 8.0 7.9 5.7 7.2 5.5 1.4 1 0 0 1 1 1 0 AAA domain Serinc PF03348.10 KOS17278.1 - 3.9 6.0 4.5 7.9 5.0 3.1 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) Zip PF02535.17 KOS17278.1 - 7 5.5 6.1 12 4.7 4.2 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Rubredoxin PF00301.15 KOS17279.1 - 0.3 10.9 2.2 6 6.8 0.1 2.5 2 0 0 2 2 2 0 Rubredoxin zf-Mss51 PF13824.1 KOS17279.1 - 0.84 9.5 6.6 4.9 7.0 0.9 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3795 PF12675.2 KOS17279.1 - 1.4 9.1 8.1 6.3 7.0 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3795) Spt4 PF06093.8 KOS17279.1 - 1.8 8.5 5.5 1.4 8.8 1.0 2.0 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger DZR PF12773.2 KOS17279.1 - 5.8 6.8 7.5 14 5.5 1.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon FBPase PF00316.15 KOS17280.1 - 6e-44 150.1 0.8 2.7e-20 72.4 0.0 3.0 3 0 0 3 3 3 3 Fructose-1-6-bisphosphatase Amidohydro_4 PF13147.1 KOS17281.1 - 1.9e-11 44.5 1.5 6.1e-05 23.1 0.2 2.4 1 1 1 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KOS17281.1 - 5.9e-05 22.8 0.4 0.034 13.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 KOS17281.1 - 7.6e-05 22.0 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KOS17281.1 - 0.00051 19.7 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase NDT80_PhoG PF05224.7 KOS17282.1 - 1.4e-35 122.9 0.0 2.3e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family PT PF04886.7 KOS17282.1 - 0.017 14.4 5.2 0.046 13.0 3.6 1.7 1 0 0 1 1 1 0 PT repeat Glyco_hydro_3 PF00933.16 KOS17283.1 - 3.7e-58 196.8 0.0 5.1e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fe_hyd_SSU PF02256.12 KOS17283.1 - 0.00096 19.1 0.0 0.58 10.1 0.0 2.5 2 0 0 2 2 2 2 Iron hydrogenase small subunit Acetyltransf_1 PF00583.19 KOS17283.1 - 0.00098 19.1 0.1 0.0045 16.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.17 KOS17283.1 - 0.019 14.4 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain CorA PF01544.13 KOS17284.1 - 5e-06 25.7 4.0 9.4e-06 24.8 2.8 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein V-SNARE_C PF12352.3 KOS17284.1 - 0.27 11.3 5.1 0.41 10.7 0.1 2.7 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus HET PF06985.6 KOS17285.1 - 4.7e-26 91.6 0.0 8.3e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Formyl_trans_N PF00551.14 KOS17286.1 - 1.4e-28 99.7 0.0 1.7e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase DUF2336 PF10098.4 KOS17286.1 - 0.0016 17.7 0.4 0.0031 16.8 0.2 1.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2336) WGG PF10273.4 KOS17287.1 - 4.3e-34 116.4 0.2 4.3e-34 116.4 0.2 1.6 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 KOS17287.1 - 0.21 11.6 0.0 0.21 11.6 0.0 2.6 3 1 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) FAM176 PF14851.1 KOS17287.1 - 5.6 6.6 8.4 5.1 6.7 0.8 2.1 2 0 0 2 2 2 0 FAM176 family Abhydrolase_3 PF07859.8 KOS17288.1 - 6.1e-38 130.5 0.0 9.5e-30 103.7 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KOS17288.1 - 7.5e-13 47.8 0.0 1.1e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KOS17288.1 - 7.9e-05 22.4 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KOS17288.1 - 0.0001 21.2 0.1 0.017 13.8 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family PAP1 PF08601.5 KOS17289.1 - 1.8e-40 139.7 3.0 2.7e-40 139.1 2.1 1.3 1 1 0 1 1 1 1 Transcription factor PAP1 BSD PF03909.12 KOS17290.1 - 1.2e-14 53.8 0.1 2.3e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 BSD domain Suf PF05843.9 KOS17290.1 - 0.014 15.1 4.5 0.27 10.9 0.2 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Sigma70_r2 PF04542.9 KOS17290.1 - 0.042 13.4 0.2 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 Sigma-70 region 2 UPRTase PF14681.1 KOS17291.1 - 2.9e-76 255.2 0.0 3.5e-76 255.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KOS17291.1 - 1.9e-05 24.3 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 KOS17291.1 - 0.1 12.3 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) S6PP_C PF08472.5 KOS17292.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal Glyco_hydro_114 PF03537.8 KOS17293.1 - 0.098 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 GTP_CH_N PF12471.3 KOS17294.1 - 9.4e-29 100.4 0.3 3.1e-18 66.0 0.0 2.2 1 1 1 2 2 2 2 GTP cyclohydrolase N terminal F-actin_cap_A PF01267.12 KOS17295.1 - 4.9e-64 216.0 0.0 3.2e-57 193.6 0.0 2.0 1 1 1 2 2 2 2 F-actin capping protein alpha subunit Transket_pyr PF02779.19 KOS17296.1 - 2.5e-46 157.3 0.1 4.1e-46 156.7 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KOS17296.1 - 1.2e-29 102.7 0.4 4e-29 101.0 0.1 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain DUF4233 PF14017.1 KOS17297.1 - 0.48 10.3 3.1 2 8.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) Ribosomal_L7Ae PF01248.21 KOS17298.1 - 1.3e-21 75.8 0.8 2.2e-21 75.1 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KOS17298.1 - 0.005 16.6 0.1 0.0074 16.1 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 ATP_bind_3 PF01171.15 KOS17299.1 - 5e-18 65.2 0.0 7.9e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 KOS17299.1 - 0.0025 18.0 0.0 0.0053 17.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 KOS17299.1 - 0.0098 14.4 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase RecR PF02132.10 KOS17299.1 - 0.012 15.0 0.4 0.012 15.0 0.3 3.1 3 0 0 3 3 3 0 RecR protein Ran-binding PF05508.6 KOS17301.1 - 3.5e-100 334.7 0.0 4.4e-100 334.4 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.22 KOS17302.1 - 1.3e-44 151.9 0.0 2.1e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KOS17302.1 - 1.4e-20 73.2 0.3 4.3e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KOS17302.1 - 8.9e-09 35.3 0.2 2.1e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KOS17302.1 - 0.00024 21.0 0.0 0.00062 19.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PipA PF07108.6 KOS17302.1 - 0.17 11.2 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 PipA protein PEPCK_ATP PF01293.15 KOS17303.1 - 1.2e-191 637.3 0.0 1.5e-191 637.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 KOS17303.1 - 0.054 13.3 0.2 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KOS17303.1 - 0.066 12.7 0.1 0.17 11.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 KOS17303.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KOS17303.1 - 0.19 11.6 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MFS_1 PF07690.11 KOS17304.1 - 3.8e-34 117.9 28.0 7.5e-34 116.9 19.1 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Wzz PF02706.10 KOS17304.1 - 0.0057 16.4 0.2 0.016 15.0 0.2 1.7 1 0 0 1 1 1 1 Chain length determinant protein ESSS PF10183.4 KOS17304.1 - 0.082 13.3 1.6 0.19 12.1 0.8 1.8 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF872 PF05915.7 KOS17304.1 - 0.9 9.4 4.1 8.2 6.3 0.0 3.4 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) SPRY PF00622.23 KOS17305.1 - 6.5e-19 68.2 0.0 1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 SPRY domain BAF1_ABF1 PF04684.8 KOS17305.1 - 0.66 8.7 26.1 0.97 8.1 18.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Macoilin PF09726.4 KOS17305.1 - 7.3 4.7 7.5 10 4.2 5.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Metallophos PF00149.23 KOS17308.1 - 5.1e-13 48.8 0.2 9e-13 48.0 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KOS17308.1 - 0.00062 19.6 0.0 0.00099 18.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SAP PF02037.22 KOS17309.1 - 1.1e-13 50.2 0.2 2.4e-13 49.2 0.2 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 KOS17309.1 - 0.057 12.9 0.5 0.16 11.5 0.3 1.8 1 1 0 1 1 1 0 HeH/LEM domain DUF4551 PF15087.1 KOS17309.1 - 1.7 6.9 4.8 2.2 6.5 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ribosomal_S3Ae PF01015.13 KOS17310.1 - 5.7e-82 273.7 5.0 6.8e-82 273.5 3.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family mRNA_cap_C PF03919.10 KOS17310.1 - 0.022 15.0 0.0 0.056 13.7 0.0 1.8 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Erythro-docking PF09277.6 KOS17310.1 - 0.035 13.7 0.2 11 5.8 0.1 2.5 2 0 0 2 2 2 0 Erythronolide synthase, docking Syntaxin PF00804.20 KOS17310.1 - 0.037 14.1 0.6 0.19 11.9 0.0 2.3 2 1 1 3 3 3 0 Syntaxin Sec23_helical PF04815.10 KOS17311.1 - 1.5e-34 117.4 0.6 3.1e-34 116.4 0.1 1.8 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KOS17311.1 - 8.7e-30 103.0 0.1 1.6e-29 102.2 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.10 KOS17311.1 - 1.7e-26 93.0 0.0 2.6e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Gelsolin PF00626.17 KOS17311.1 - 8.2e-07 28.6 0.0 1.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L11_N PF03946.9 KOS17312.1 - 1.2e-17 63.0 0.1 2e-17 62.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KOS17312.1 - 5.5e-12 45.6 0.3 9.9e-12 44.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Myb_DNA-binding PF00249.26 KOS17313.1 - 5.7e-15 55.1 5.5 2.2e-08 34.0 0.3 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KOS17313.1 - 7.4e-15 54.7 7.9 3.1e-09 36.7 0.6 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_23 PF13384.1 KOS17313.1 - 0.017 14.7 0.3 0.041 13.5 0.2 1.7 1 0 0 1 1 1 0 Homeodomain-like domain TipAS PF07739.8 KOS17313.1 - 0.018 15.3 5.1 0.2 11.9 1.5 2.2 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain DUF1178 PF06676.6 KOS17313.1 - 0.11 12.7 0.2 0.11 12.7 0.1 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1178) Sec39 PF08314.6 KOS17314.1 - 1.2e-39 135.9 2.8 1.3e-39 135.7 2.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 RRM_1 PF00076.17 KOS17315.1 - 4.3e-20 71.1 0.0 7.2e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS17315.1 - 1.5e-15 56.9 0.0 2.5e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS17315.1 - 1.5e-11 43.9 0.0 2.2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldedh PF00171.17 KOS17316.1 - 2.3e-118 395.4 2.7 2.8e-118 395.1 1.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Como_SCP PF02248.11 KOS17316.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Small coat protein AAA PF00004.24 KOS17318.1 - 8.9e-42 142.4 0.0 2.3e-41 141.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KOS17318.1 - 9.5e-25 86.2 0.0 8.5e-24 83.2 0.1 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KOS17318.1 - 4.1e-18 65.0 5.1 1.3e-17 63.3 3.2 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.7 KOS17318.1 - 5.3e-07 28.9 0.0 8.3e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KOS17318.1 - 3.7e-06 27.7 0.1 1.8e-05 25.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 KOS17318.1 - 1.4e-05 24.0 0.0 3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 KOS17318.1 - 1.8e-05 24.2 0.0 4.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KOS17318.1 - 2.4e-05 24.2 0.0 7e-05 22.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KOS17318.1 - 2.9e-05 24.1 0.1 0.0022 18.1 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KOS17318.1 - 5.4e-05 22.9 0.0 0.00039 20.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KOS17318.1 - 5.8e-05 23.2 0.0 0.0092 16.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 KOS17318.1 - 6.2e-05 23.0 0.1 0.0042 17.0 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain DUF815 PF05673.8 KOS17318.1 - 9.1e-05 21.4 0.1 0.00066 18.6 0.0 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KOS17318.1 - 0.00092 19.1 0.0 0.0024 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain PrkA PF06798.7 KOS17318.1 - 0.0013 18.1 0.9 0.0026 17.0 0.6 1.5 1 1 0 1 1 1 1 PrkA serine protein kinase C-terminal domain AAA_25 PF13481.1 KOS17318.1 - 0.0019 17.6 0.1 0.24 10.8 0.1 2.5 1 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 KOS17318.1 - 0.0039 16.8 0.3 0.027 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KOS17318.1 - 0.0072 16.2 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KOS17318.1 - 0.01 16.1 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 KOS17318.1 - 0.012 15.5 0.3 2.3 8.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KOS17318.1 - 0.019 14.0 0.0 0.074 12.1 0.0 1.9 1 1 1 2 2 2 0 Zeta toxin Mg_chelatase PF01078.16 KOS17318.1 - 0.021 14.0 0.0 0.063 12.4 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KOS17318.1 - 0.022 14.5 0.0 0.073 12.8 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 KOS17318.1 - 0.025 13.8 0.3 0.082 12.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 KOS17318.1 - 0.042 13.4 0.0 0.61 9.7 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 KOS17318.1 - 0.07 13.1 0.2 0.38 10.7 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KOS17318.1 - 0.087 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 KOS17318.1 - 0.1 12.3 0.8 0.74 9.4 0.0 2.6 2 2 1 3 3 3 0 Archaeal ATPase Torsin PF06309.6 KOS17318.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Torsin Med11 PF10280.4 KOS17320.1 - 1.4e-26 92.8 0.0 3.8e-26 91.4 0.0 1.6 1 1 0 1 1 1 1 Mediator complex protein WD40 PF00400.27 KOS17321.1 - 5.9e-50 165.4 19.9 5.2e-08 32.4 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KOS17321.1 - 2.6e-36 124.8 0.3 4e-36 124.2 0.2 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 KOS17321.1 - 1.2e-05 25.1 0.0 0.019 14.7 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 KOS17321.1 - 0.00061 19.4 0.1 0.0016 18.1 0.0 1.8 2 0 0 2 2 2 1 LisH Nup160 PF11715.3 KOS17321.1 - 0.047 11.8 0.3 25 2.8 0.0 3.1 2 1 0 3 3 3 0 Nucleoporin Nup120/160 DUF3374 PF11854.3 KOS17321.1 - 0.22 9.7 0.0 0.31 9.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3374) Ytp1 PF10355.4 KOS17323.1 - 8.4e-82 274.4 14.1 8.4e-82 274.4 9.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KOS17323.1 - 3.4e-30 103.7 0.4 3.4e-30 103.7 0.3 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) JAB PF01398.16 KOS17324.1 - 1.8e-12 46.9 0.0 3.6e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 KOS17324.1 - 4.4e-10 39.5 0.2 2e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.1 KOS17324.1 - 3.8e-05 23.1 0.0 9.9e-05 21.8 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain HEPN PF05168.9 KOS17324.1 - 0.1 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 HEPN domain Prefoldin_2 PF01920.15 KOS17325.1 - 6.5e-15 54.8 8.5 7.4e-15 54.6 5.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Rootletin PF15035.1 KOS17325.1 - 0.005 16.8 2.5 0.0053 16.7 1.7 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DivIC PF04977.10 KOS17325.1 - 0.072 12.5 10.7 0.39 10.2 7.4 2.0 1 1 0 1 1 1 0 Septum formation initiator Peptidase_S49_N PF08496.5 KOS17325.1 - 0.074 12.8 2.8 0.079 12.7 2.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal IncA PF04156.9 KOS17325.1 - 0.15 11.6 6.0 0.16 11.5 4.2 1.2 1 0 0 1 1 1 0 IncA protein CENP-K PF11802.3 KOS17325.1 - 0.26 10.5 4.6 0.28 10.3 3.2 1.1 1 0 0 1 1 1 0 Centromere-associated protein K OmpH PF03938.9 KOS17325.1 - 0.37 10.7 8.2 0.42 10.5 5.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2175 PF09943.4 KOS17325.1 - 0.47 10.5 2.4 0.53 10.3 1.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Atg14 PF10186.4 KOS17325.1 - 1 8.2 4.3 1 8.2 3.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 60KD_IMP PF02096.15 KOS17325.1 - 1 8.9 4.7 1.3 8.6 3.3 1.4 1 1 0 1 1 1 0 60Kd inner membrane protein COX16 PF14138.1 KOS17325.1 - 2.7 8.2 5.4 6.8 6.9 3.8 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DUF3847 PF12958.2 KOS17325.1 - 4.3 7.1 8.2 3.4 7.5 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3847) PH PF00169.24 KOS17326.1 - 3e-05 24.1 0.0 4.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.13 KOS17326.1 - 0.023 14.1 0.3 0.038 13.5 0.2 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CK2S PF15011.1 KOS17326.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 Casein Kinase 2 substrate SRP72 PF08492.7 KOS17327.1 - 3.9e-15 55.9 6.6 3.9e-15 55.9 4.6 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_2 PF07719.12 KOS17327.1 - 6e-05 22.6 18.5 0.87 9.6 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 KOS17327.1 - 0.0032 17.5 9.0 0.43 10.7 2.2 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 KOS17327.1 - 0.059 13.3 0.4 16 5.7 0.0 3.8 4 0 0 4 4 4 0 PPR repeat TPR_19 PF14559.1 KOS17327.1 - 0.28 11.5 32.1 0.61 10.4 0.2 6.4 4 3 2 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 KOS17327.1 - 1.7 9.4 34.2 8.7 7.2 0.5 8.4 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_3 PF07720.7 KOS17327.1 - 6.2 6.7 6.5 9.6 6.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KOS17327.1 - 7 6.5 16.2 1.6 8.5 0.4 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat Herpes_UL32 PF06070.6 KOS17328.1 - 0.011 14.1 1.7 0.011 14.2 1.2 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Sec7 PF01369.15 KOS17329.1 - 8.2e-38 129.9 0.0 1.3e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KOS17329.1 - 5.1e-05 23.4 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KOS17329.1 - 0.0006 19.9 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 PH domain Adaptin_N PF01602.15 KOS17330.1 - 8.7e-143 476.4 0.5 1.1e-142 476.1 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KOS17330.1 - 6.6e-18 65.1 0.1 1.6e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KOS17330.1 - 2.1e-07 31.1 1.4 0.019 15.2 0.1 4.2 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 KOS17330.1 - 0.0013 18.5 3.3 0.054 13.3 0.7 3.2 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 KOS17330.1 - 0.0026 17.5 0.1 1.2 9.0 0.0 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 KOS17330.1 - 0.0031 17.9 2.6 11 6.6 0.1 4.6 3 1 0 3 3 3 1 HEAT-like repeat TIP120 PF08623.5 KOS17330.1 - 0.012 15.1 0.1 0.045 13.3 0.0 2.0 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) HEAT PF02985.17 KOS17330.1 - 0.016 15.2 3.7 13 6.1 0.0 5.0 5 1 1 6 6 6 0 HEAT repeat RIX1 PF08167.7 KOS17330.1 - 0.025 14.2 0.0 0.23 11.1 0.0 2.6 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Arm PF00514.18 KOS17330.1 - 0.071 12.9 0.2 80 3.2 0.1 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat zf-rbx1 PF12678.2 KOS17331.1 - 1.8e-11 43.9 3.9 3.4e-11 43.0 2.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KOS17331.1 - 4.1e-11 42.5 6.8 7.6e-11 41.6 4.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KOS17331.1 - 4e-07 29.6 5.9 3.5e-06 26.5 4.4 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS17331.1 - 7e-06 25.6 3.9 1.3e-05 24.7 2.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KOS17331.1 - 7.8e-05 22.2 5.1 0.00017 21.1 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS17331.1 - 8.3e-05 22.5 4.1 0.00025 20.9 2.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KOS17331.1 - 0.00023 20.9 1.4 0.0005 19.8 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KOS17331.1 - 0.012 15.2 4.8 0.035 13.8 3.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KOS17331.1 - 0.072 12.9 1.2 0.17 11.7 0.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KOS17331.1 - 0.16 11.5 2.0 0.2 11.2 0.2 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KOS17331.1 - 2.2 8.2 4.3 8 6.5 3.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Peptidase_M14 PF00246.19 KOS17332.1 - 5.5e-38 131.1 0.0 7.4e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase MAPEG PF01124.13 KOS17333.1 - 2e-22 79.1 3.5 2.3e-22 78.9 2.4 1.1 1 0 0 1 1 1 1 MAPEG family Clathrin_lg_ch PF01086.12 KOS17334.1 - 3e-69 233.3 5.0 3.4e-69 233.2 3.5 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF4407 PF14362.1 KOS17334.1 - 4.5 6.1 7.3 1.3 7.8 2.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CTD_bind PF04818.8 KOS17335.1 - 2.3e-19 69.3 0.8 4.5e-19 68.4 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. DUF3277 PF11681.3 KOS17335.1 - 0.02 14.4 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) CTK3 PF12243.3 KOS17335.1 - 0.062 12.9 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 COX7a PF02238.10 KOS17336.1 - 0.017 14.8 0.2 0.03 14.0 0.0 1.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa Cation_efflux PF01545.16 KOS17337.1 - 2.2e-29 102.4 3.5 2.9e-29 102.0 2.4 1.2 1 0 0 1 1 1 1 Cation efflux family Nnf1 PF03980.9 KOS17337.1 - 0.017 15.0 0.2 0.04 13.9 0.1 1.5 1 0 0 1 1 1 0 Nnf1 Glyco_transf_8 PF01501.15 KOS17338.1 - 7.8e-35 120.3 0.1 1.8e-34 119.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KOS17338.1 - 0.0051 16.2 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Vps5 PF09325.5 KOS17340.1 - 9e-87 290.2 3.7 1.4e-86 289.5 2.6 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KOS17340.1 - 2.3e-24 85.3 0.0 5.3e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.4 KOS17340.1 - 0.002 17.0 1.4 0.0033 16.4 0.9 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3_WASP_bdg PF10456.4 KOS17340.1 - 0.0027 16.9 0.2 0.0051 16.1 0.1 1.5 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein BAR PF03114.13 KOS17340.1 - 0.13 11.7 7.7 0.27 10.6 5.4 1.5 1 1 0 1 1 1 0 BAR domain Atg14 PF10186.4 KOS17340.1 - 0.14 11.1 3.1 0.21 10.4 2.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DnaJ PF00226.26 KOS17341.1 - 6.4e-20 70.6 5.1 8.2e-20 70.3 1.6 2.5 2 0 0 2 2 2 1 DnaJ domain Metallophos PF00149.23 KOS17342.1 - 2e-14 53.4 1.1 5.4e-14 52.0 0.8 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KOS17342.1 - 1.3e-06 28.2 0.6 6.6e-06 26.0 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 KOS17342.1 - 0.074 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Prothymosin PF03247.9 KOS17342.1 - 2.3 8.4 17.5 1.1 9.3 4.0 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family HSP90 PF00183.13 KOS17344.1 - 1e-255 849.2 35.0 1.2e-255 848.9 24.3 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 KOS17344.1 - 1.4e-11 44.2 0.3 1.4e-11 44.2 0.2 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KOS17344.1 - 1.9e-11 43.6 0.1 3.6e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 KOS17344.1 - 0.017 15.4 0.8 0.017 15.4 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) LOH1CR12 PF10158.4 KOS17344.1 - 0.082 12.7 0.3 0.082 12.7 0.2 2.2 2 0 0 2 2 2 0 Tumour suppressor protein Peptidase_S10 PF00450.17 KOS17344.1 - 1.2 8.2 4.8 0.32 10.0 0.1 2.2 1 1 0 2 2 2 0 Serine carboxypeptidase DUF1510 PF07423.6 KOS17344.1 - 1.8 7.8 24.4 0.22 10.8 10.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) PVL_ORF50 PF07768.6 KOS17344.1 - 2.7 8.0 16.2 1.2 9.1 4.3 2.8 2 0 0 2 2 2 0 PVL ORF-50-like family Flavin_Reduct PF01613.13 KOS17345.1 - 8.8e-31 106.8 0.0 1.2e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain GST_N_3 PF13417.1 KOS17347.1 - 2e-12 47.1 0.0 1.5e-10 41.1 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KOS17347.1 - 3e-11 43.1 0.0 6.9e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KOS17347.1 - 3.5e-11 42.8 0.1 7.6e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KOS17347.1 - 5.7e-09 36.0 0.0 5.1e-07 29.7 0.0 2.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KOS17347.1 - 8.9e-08 32.0 0.0 2.2e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KOS17347.1 - 2e-07 31.3 0.1 3.5e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain H2TH PF06831.9 KOS17348.1 - 3.1e-23 81.3 0.0 4.3e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 KOS17348.1 - 2.1e-06 28.0 0.0 3.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.6 KOS17348.1 - 0.016 13.8 0.0 0.018 13.5 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Acetyltransf_1 PF00583.19 KOS17349.1 - 3.6e-19 68.5 0.0 5e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS17349.1 - 3.1e-09 36.8 0.0 6.1e-09 35.9 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS17349.1 - 1.5e-08 34.7 0.0 2.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KOS17349.1 - 4.5e-08 32.7 0.0 7.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KOS17349.1 - 3.2e-06 27.0 0.1 4.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS17349.1 - 0.00047 20.0 0.0 0.0009 19.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KOS17349.1 - 0.0066 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KOS17349.1 - 0.06 12.9 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PAXNEB PF05625.6 KOS17350.1 - 0.04 12.7 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 PAXNEB protein SnoaL_4 PF13577.1 KOS17350.1 - 0.062 13.2 0.1 1 9.3 0.0 2.3 2 0 0 2 2 2 0 SnoaL-like domain DUF3783 PF12646.2 KOS17350.1 - 0.18 11.5 0.3 0.42 10.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) DUF2838 PF10998.3 KOS17351.1 - 7.4e-45 151.3 7.4 7.4e-45 151.3 5.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Apolipoprotein PF01442.13 KOS17351.1 - 0.19 11.2 4.5 0.11 11.9 1.8 1.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain IncA PF04156.9 KOS17351.1 - 0.32 10.5 1.9 0.55 9.8 1.3 1.2 1 0 0 1 1 1 0 IncA protein Dicty_CAR PF05462.6 KOS17353.1 - 5.7e-11 41.8 5.9 5.7e-11 41.8 4.1 1.6 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 KOS17353.1 - 1.7e-06 27.3 1.6 2.5e-06 26.8 1.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 KOS17353.1 - 3.6e-06 26.6 6.7 3.6e-06 26.6 4.7 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.4 KOS17353.1 - 0.0022 17.1 0.9 0.0039 16.4 0.6 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2721 PF11026.3 KOS17353.1 - 0.03 13.9 2.2 0.064 12.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) TPR_MLP1_2 PF07926.7 KOS17354.1 - 0.054 13.2 3.8 0.41 10.3 1.1 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 KOS17354.1 - 1.4 8.4 4.4 1.7 8.1 1.3 2.2 2 0 0 2 2 2 0 IncA protein FAD_binding_1 PF00667.15 KOS17356.1 - 7.3e-44 149.8 0.0 1.1e-43 149.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KOS17356.1 - 1e-10 42.1 0.1 6.9e-10 39.4 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain PS_Dcarbxylase PF02666.10 KOS17357.1 - 8.8e-82 273.2 0.0 1.4e-80 269.3 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl PF00364.17 KOS17357.1 - 0.0074 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Peptidase_C12 PF01088.16 KOS17358.1 - 1.2e-65 220.6 0.0 1.5e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Xan_ur_permease PF00860.15 KOS17359.1 - 9.9e-26 90.1 30.4 1.4e-14 53.4 5.8 2.2 2 0 0 2 2 2 2 Permease family N2227 PF07942.7 KOS17360.1 - 4e-87 291.6 0.0 2.2e-76 256.4 0.0 2.1 2 0 0 2 2 2 2 N2227-like protein Methyltransf_23 PF13489.1 KOS17360.1 - 0.00017 21.3 0.1 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS17360.1 - 0.079 13.4 0.0 0.42 11.1 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 KOS17360.1 - 0.9 9.5 5.1 0.24 11.4 0.8 2.1 2 1 0 2 2 2 0 Methyltransferase domain chaperone_DMP PF10448.4 KOS17361.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 20S proteasome chaperone ABC_membrane_3 PF13748.1 KOS17361.1 - 0.11 11.5 0.1 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region ABC_membrane PF00664.18 KOS17363.1 - 1.1e-42 146.4 11.1 1.4e-42 146.0 7.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KOS17363.1 - 5.8e-34 117.3 0.0 1.7e-33 115.8 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KOS17363.1 - 9e-05 22.5 2.3 0.41 10.5 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KOS17363.1 - 0.00022 21.3 0.2 0.0011 19.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS17363.1 - 0.00027 20.9 0.3 0.00083 19.3 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 KOS17363.1 - 0.00092 18.4 2.5 0.01 15.1 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KOS17363.1 - 0.0012 19.6 0.0 0.0031 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KOS17363.1 - 0.0016 18.6 0.0 0.018 15.2 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KOS17363.1 - 0.004 16.6 0.0 0.01 15.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.4 KOS17363.1 - 0.0082 14.7 0.6 0.015 13.9 0.1 1.6 2 0 0 2 2 2 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 KOS17363.1 - 0.012 15.4 1.1 0.12 12.2 0.8 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 KOS17363.1 - 0.018 14.7 0.1 0.072 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KOS17363.1 - 0.018 14.4 0.8 0.2 11.0 0.6 2.3 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KOS17363.1 - 0.033 13.5 0.1 0.29 10.5 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.1 KOS17363.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KOS17363.1 - 0.086 12.7 0.0 2.6 7.9 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_10 PF12846.2 KOS17363.1 - 0.11 11.8 0.8 0.43 9.9 0.3 2.0 2 0 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 KOS17363.1 - 0.18 11.0 0.1 0.36 10.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Abhydrolase_6 PF12697.2 KOS17364.1 - 7.8e-23 81.5 0.8 1e-22 81.1 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KOS17364.1 - 5.8e-22 77.3 0.1 1.9e-18 66.0 0.0 2.7 3 0 0 3 3 3 2 Putative lysophospholipase Abhydrolase_5 PF12695.2 KOS17364.1 - 2.5e-18 66.2 0.0 3.3e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS17364.1 - 3.9e-05 23.3 0.0 0.00023 20.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KOS17364.1 - 0.0063 15.4 0.0 0.014 14.2 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 KOS17364.1 - 0.011 14.9 0.2 3.4 6.8 0.0 2.5 2 1 1 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KOS17364.1 - 0.013 15.0 0.3 0.11 12.0 0.2 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 KOS17364.1 - 0.072 12.5 0.1 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 Putative esterase Atx10homo_assoc PF09759.4 KOS17365.1 - 4.8e-11 42.2 0.0 2.2e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain PNP_UDP_1 PF01048.15 KOS17366.1 - 5.9e-38 130.1 0.5 7.3e-38 129.8 0.4 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2694 PF10904.3 KOS17366.1 - 0.04 13.9 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) AA_permease_2 PF13520.1 KOS17367.1 - 3.8e-75 253.0 22.7 4.8e-75 252.7 15.7 1.1 1 0 0 1 1 1 1 Amino acid permease Arrestin_C PF02752.17 KOS17370.1 - 2.8e-05 24.2 0.0 3.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain RHS_repeat PF05593.9 KOS17370.1 - 0.079 13.1 0.0 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 RHS Repeat Miro PF08477.8 KOS17371.1 - 2e-34 118.6 0.0 1e-18 67.9 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 KOS17371.1 - 1.9e-22 79.4 0.0 6.6e-15 54.8 0.0 2.1 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 KOS17371.1 - 1.7e-08 34.3 0.0 0.00049 20.0 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 KOS17371.1 - 2.2e-08 34.0 0.0 0.00066 19.5 0.0 3.1 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.1 KOS17371.1 - 7.5e-06 26.1 0.0 0.02 15.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain EF-hand_7 PF13499.1 KOS17371.1 - 1.7e-05 24.8 0.1 5.2e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair AAA_16 PF13191.1 KOS17371.1 - 3.2e-05 23.9 0.0 0.023 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KOS17371.1 - 3.3e-05 23.3 0.0 0.0033 16.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF_assoc_2 PF08356.7 KOS17371.1 - 4.3e-05 23.1 0.0 8.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 EF hand associated GTP_EFTU PF00009.22 KOS17371.1 - 4.6e-05 22.9 0.0 0.76 9.1 0.0 3.2 2 1 0 3 3 3 2 Elongation factor Tu GTP binding domain EF-hand_1 PF00036.27 KOS17371.1 - 0.00039 19.5 0.0 0.0011 18.0 0.0 1.8 1 0 0 1 1 1 1 EF hand AAA_28 PF13521.1 KOS17371.1 - 0.00094 19.1 0.0 1.9 8.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain EF-hand_6 PF13405.1 KOS17371.1 - 0.0019 17.9 0.1 0.0052 16.5 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain MobB PF03205.9 KOS17371.1 - 0.0029 17.3 0.0 0.71 9.5 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KOS17371.1 - 0.0049 17.1 0.0 0.31 11.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 KOS17371.1 - 0.007 15.5 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 EF-hand_5 PF13202.1 KOS17371.1 - 0.013 14.8 0.0 0.041 13.2 0.0 1.9 1 0 0 1 1 1 0 EF hand DUF815 PF05673.8 KOS17371.1 - 0.032 13.1 0.0 4.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.13 KOS17371.1 - 0.037 13.0 0.0 0.55 9.1 0.0 2.2 2 0 0 2 2 2 0 Septin EF-hand_10 PF14788.1 KOS17371.1 - 0.04 13.5 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 EF hand RNA_helicase PF00910.17 KOS17371.1 - 0.056 13.6 0.0 12 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.1 KOS17371.1 - 0.075 13.3 0.1 0.41 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KOS17371.1 - 0.077 12.8 0.0 4.5 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KOS17371.1 - 0.086 12.4 0.0 7.4 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KOS17371.1 - 0.11 12.1 0.0 3.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Pox_MCEL PF03291.11 KOS17372.1 - 4.8e-63 213.0 0.0 1.3e-43 149.1 0.0 2.5 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 KOS17372.1 - 5.9e-09 36.2 0.0 0.0056 17.1 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KOS17372.1 - 2.7e-08 33.6 0.0 5.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS17372.1 - 1.4e-06 28.7 0.0 2.9e-05 24.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS17372.1 - 2.2e-06 28.2 0.0 5.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS17372.1 - 1.6e-05 24.5 0.0 0.00019 21.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS17372.1 - 2.1e-05 24.8 0.0 4.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Raftlin PF15250.1 KOS17372.1 - 0.021 13.4 0.1 0.021 13.4 0.0 1.6 2 0 0 2 2 2 0 Raftlin NNMT_PNMT_TEMT PF01234.12 KOS17372.1 - 0.033 13.1 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 KOS17372.1 - 0.046 12.7 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase RPN7 PF10602.4 KOS17373.1 - 1.1e-53 181.2 0.4 2.1e-53 180.3 0.3 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KOS17373.1 - 1.3e-14 54.4 0.0 3.9e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 PCI domain TPR_14 PF13428.1 KOS17373.1 - 0.31 11.7 3.0 32 5.5 0.3 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_tran_2 PF12848.2 KOS17373.1 - 7.9 6.4 7.5 18 5.2 0.0 3.5 3 0 0 3 3 3 0 ABC transporter Acetyltransf_1 PF00583.19 KOS17374.1 - 5.7e-07 29.4 0.1 1.3e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KOS17374.1 - 0.0019 18.3 0.2 0.018 15.1 0.1 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KOS17374.1 - 0.0067 16.5 0.1 0.017 15.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KOS17374.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KOS17374.1 - 0.062 13.0 0.1 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein Bac_surface_Ag PF01103.18 KOS17376.1 - 1.2e-33 117.0 0.0 1.5e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Surface antigen ABC2_membrane PF01061.19 KOS17377.1 - 1.5e-99 331.3 50.9 1.4e-50 171.3 13.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KOS17377.1 - 7.1e-34 117.0 0.0 7e-17 62.0 0.0 3.5 3 1 1 4 4 3 2 ABC transporter PDR_CDR PF06422.7 KOS17377.1 - 2.8e-31 107.2 5.2 1e-28 98.9 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 KOS17377.1 - 1e-20 73.6 0.0 2.7e-20 72.2 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 KOS17377.1 - 1.6e-07 31.4 0.4 3e-05 24.1 0.1 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 KOS17377.1 - 3e-07 30.0 0.0 0.00066 19.1 0.0 2.8 3 0 0 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.2 KOS17377.1 - 6.1e-06 25.4 36.7 2.8e-05 23.3 5.1 3.4 2 2 1 3 3 3 2 ABC-2 family transporter protein DUF258 PF03193.11 KOS17377.1 - 1.5e-05 24.2 0.0 0.00086 18.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KOS17377.1 - 1.6e-05 24.7 0.0 0.039 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KOS17377.1 - 0.00012 21.4 0.4 0.023 14.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 KOS17377.1 - 0.00029 20.3 0.4 0.0069 15.8 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KOS17377.1 - 0.00056 20.7 0.0 1.2 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KOS17377.1 - 0.00057 20.0 0.0 0.36 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KOS17377.1 - 0.004 16.8 0.2 2.5 7.7 0.1 2.8 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 KOS17377.1 - 0.0048 16.6 1.5 3.9 7.2 0.0 3.2 4 0 0 4 4 2 2 Part of AAA domain AAA_21 PF13304.1 KOS17377.1 - 0.0061 16.5 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KOS17377.1 - 0.014 15.6 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KOS17377.1 - 0.014 15.6 0.1 0.98 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KOS17377.1 - 0.041 13.0 0.0 8.2 5.5 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 KOS17377.1 - 0.05 13.2 0.1 4.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 KOS17377.1 - 0.095 12.1 2.4 6.8 6.0 0.1 3.3 3 0 0 3 3 3 0 AAA-like domain AAA_28 PF13521.1 KOS17377.1 - 0.099 12.5 0.1 1 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KOS17377.1 - 0.12 11.9 0.1 7.7 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KOS17377.1 - 0.13 12.5 0.0 0.43 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain Miro PF08477.8 KOS17377.1 - 0.17 12.4 0.0 23 5.5 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Arch_ATPase PF01637.13 KOS17377.1 - 0.17 11.5 0.0 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase T2SE PF00437.15 KOS17377.1 - 0.28 10.0 0.0 1.8 7.4 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.1 KOS17377.1 - 0.86 8.5 0.0 1.4 7.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain UvrD_C PF13361.1 KOS17378.1 - 2.1e-78 264.2 0.0 3.5e-78 263.5 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KOS17378.1 - 2.7e-64 217.4 0.2 3.5e-63 213.8 0.1 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KOS17378.1 - 1.2e-14 54.3 0.0 3.4e-14 52.8 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KOS17378.1 - 2.7e-12 46.2 1.2 2.7e-12 46.2 0.8 3.3 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KOS17378.1 - 1.1e-06 28.4 5.2 2.1e-05 24.2 0.1 3.0 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 KOS17378.1 - 0.00012 21.6 0.0 0.89 9.0 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 KOS17378.1 - 0.0017 17.7 0.0 0.0071 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KOS17378.1 - 0.01 15.3 0.2 0.063 12.8 0.2 2.4 1 1 0 1 1 1 0 AAA domain TSC21 PF15217.1 KOS17379.1 - 0.024 14.3 0.0 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 TSC21 family CcmD PF04995.9 KOS17379.1 - 0.84 9.4 3.6 0.89 9.3 0.1 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF2014 PF09427.5 KOS17380.1 - 6.1e-62 209.1 5.4 1.4e-61 207.8 3.8 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF2014) Pectate_lyase_3 PF12708.2 KOS17381.1 - 3.3e-31 109.1 10.4 5.5e-18 65.9 3.6 2.8 2 1 0 2 2 2 2 Pectate lyase superfamily protein ESCRT-II PF05871.7 KOS17382.1 - 7.4e-45 152.2 0.0 1e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit PPR_3 PF13812.1 KOS17382.1 - 0.84 10.0 3.2 15 6.2 0.0 3.5 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PTCB-BRCT PF12738.2 KOS17383.1 - 5.6e-29 99.7 0.5 6.9e-20 70.6 0.1 4.8 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.21 KOS17383.1 - 1e-26 92.9 0.0 3.2e-10 39.9 0.0 5.9 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain Nop14 PF04147.7 KOS17383.1 - 0.32 8.8 7.3 0.49 8.2 5.0 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KOS17383.1 - 0.79 9.2 5.8 1.4 8.3 4.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KOS17383.1 - 6 7.1 12.1 11 6.2 7.6 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Hexokinase_2 PF03727.11 KOS17384.1 - 7.4e-35 120.3 0.0 2.6e-27 95.6 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KOS17384.1 - 7.8e-25 87.4 0.0 1.1e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Glucosamine_iso PF01182.15 KOS17385.1 - 9.8e-25 87.4 0.0 1.5e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Foie-gras_1 PF11817.3 KOS17386.1 - 4.5e-74 249.0 2.3 1.3e-69 234.4 2.2 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun PF07919.7 KOS17387.1 - 2.1e-72 244.2 0.0 2.3e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.2 KOS17387.1 - 0.0008 19.1 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Pkinase PF00069.20 KOS17388.1 - 1.8e-52 178.0 0.0 2.3e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17388.1 - 5.6e-30 104.2 0.0 7.1e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS17388.1 - 0.0006 18.8 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KOS17388.1 - 0.0052 15.8 0.0 0.0088 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KOS17388.1 - 0.01 15.5 0.2 0.023 14.4 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA PF00004.24 KOS17389.1 - 4.1e-17 62.6 0.0 7e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Med31 PF05669.7 KOS17389.1 - 0.089 12.5 0.5 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 SOH1 AAA_22 PF13401.1 KOS17389.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TFIIE_beta PF02186.10 KOS17390.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 TFIIE beta subunit core domain Cyt-b5 PF00173.23 KOS17391.1 - 6.3e-24 83.5 0.3 1.2e-23 82.6 0.2 1.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain zf-H2C2_2 PF13465.1 KOS17392.1 - 9.7e-08 31.9 1.8 9.7e-08 31.9 1.2 4.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 KOS17392.1 - 4.1e-06 26.8 9.4 3.5e-05 23.8 2.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS17392.1 - 0.00014 21.9 3.7 0.00014 21.9 2.6 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger Toxin_62 PF15540.1 KOS17392.1 - 0.045 13.8 0.3 0.089 12.8 0.2 1.5 1 0 0 1 1 1 0 Putative toxin 62 zf-C2H2_6 PF13912.1 KOS17392.1 - 5 7.1 6.1 0.54 10.2 0.9 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Nramp PF01566.13 KOS17393.1 - 1.3e-90 303.7 24.5 1.3e-90 303.7 17.0 1.9 3 0 0 3 3 3 1 Natural resistance-associated macrophage protein VHS PF00790.14 KOS17394.1 - 8.7e-20 70.7 0.0 1.5e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KOS17394.1 - 2e-10 40.5 1.4 3.9e-10 39.5 0.9 1.4 1 0 0 1 1 1 1 GAT domain Peptidase_M16_C PF05193.16 KOS17394.1 - 0.06 13.0 2.2 3.7 7.1 0.1 2.5 2 0 0 2 2 2 0 Peptidase M16 inactive domain RXT2_N PF08595.6 KOS17395.1 - 2.1e-38 131.4 0.3 7.4e-38 129.6 0.0 2.1 2 0 0 2 2 2 1 RXT2-like, N-terminal MAGP PF05507.6 KOS17395.1 - 5.8 6.7 6.4 0.94 9.2 0.4 2.4 2 1 1 3 3 3 0 Microfibril-associated glycoprotein (MAGP) NUC153 PF08159.7 KOS17396.1 - 3.2e-13 48.9 1.8 5.8e-13 48.1 1.3 1.4 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 KOS17396.1 - 4.5e-06 26.3 0.1 0.0007 19.3 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat Aminotran_1_2 PF00155.16 KOS17397.1 - 6.1e-39 133.9 0.0 8.2e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Sugar_tr PF00083.19 KOS17398.1 - 1.8e-41 142.2 23.6 2.3e-41 141.8 16.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS17398.1 - 3e-16 59.1 25.5 5e-16 58.3 17.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily NMO PF03060.10 KOS17399.1 - 1.1e-63 215.4 1.1 1.6e-63 214.8 0.8 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KOS17399.1 - 1.5e-07 30.6 0.9 0.0042 16.0 0.0 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KOS17399.1 - 0.0051 15.6 0.3 0.0094 14.8 0.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase F-box-like PF12937.2 KOS17400.1 - 0.0067 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like Med13_C PF06333.7 KOS17401.1 - 3.7e-41 141.0 0.2 4.1e-41 140.8 0.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal An_peroxidase PF03098.10 KOS17402.1 - 3.1e-95 319.5 0.0 3.9e-93 312.6 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KOS17402.1 - 0.023 13.2 0.0 0.037 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 E1-E2_ATPase PF00122.15 KOS17404.1 - 4.4e-51 173.1 2.1 9.3e-51 172.0 1.5 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KOS17404.1 - 1e-33 116.4 7.6 1e-33 116.4 5.2 2.6 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KOS17404.1 - 1.1e-33 117.4 1.1 1.8e-32 113.5 0.7 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KOS17404.1 - 1.4e-16 61.2 0.0 1.8e-14 54.3 0.0 3.3 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS17404.1 - 9.7e-14 51.1 0.0 2.4e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KOS17404.1 - 2.8e-10 39.5 0.0 1.3e-09 37.4 0.0 2.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KOS17404.1 - 2.9e-05 23.7 0.5 6e-05 22.7 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.4 KOS17404.1 - 0.28 11.5 8.4 0.16 12.3 1.7 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) DUF2207 PF09972.4 KOS17404.1 - 0.49 8.9 6.0 3 6.2 0.0 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Acetyltransf_7 PF13508.1 KOS17405.1 - 3.3e-05 23.9 0.0 6.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS17405.1 - 4e-05 23.5 0.7 9.6e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KOS17405.1 - 0.00018 21.5 0.5 0.00045 20.3 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS17405.1 - 0.096 12.5 0.3 0.37 10.6 0.2 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KOS17405.1 - 0.19 11.3 1.6 0.34 10.5 0.7 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SET PF00856.23 KOS17406.1 - 6e-07 29.9 0.0 6.3e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 SET domain MOZ_SAS PF01853.13 KOS17407.1 - 1.5e-78 262.3 0.0 2.1e-78 261.9 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Collagen PF01391.13 KOS17407.1 - 1.7e-06 27.4 6.8 1.7e-06 27.4 4.7 2.3 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) ATG13 PF10033.4 KOS17408.1 - 2.3e-60 203.9 0.0 4.8e-58 196.3 0.0 2.4 1 1 0 1 1 1 1 Autophagy-related protein 13 BTB PF00651.26 KOS17409.1 - 1.8e-07 31.1 0.0 4.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Mito_carr PF00153.22 KOS17410.1 - 2.3e-70 232.3 2.2 1.3e-25 88.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein M-factor PF03855.8 KOS17410.1 - 0.18 11.8 1.2 1.4 8.9 0.0 2.7 3 0 0 3 3 3 0 M-factor Acyl-CoA_dh_M PF02770.14 KOS17411.1 - 0.06 12.8 0.2 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain ENTH PF01417.15 KOS17412.1 - 1.3e-11 44.4 0.0 1.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ENTH PF01417.15 KOS17413.1 - 4.1e-30 104.2 0.4 7.1e-30 103.4 0.3 1.4 1 0 0 1 1 1 1 ENTH domain PAT1 PF09770.4 KOS17413.1 - 6 4.9 53.2 0.062 11.5 31.7 1.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 EF-hand_1 PF00036.27 KOS17414.1 - 8e-15 52.9 7.4 5.1e-05 22.2 0.2 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KOS17414.1 - 2e-14 53.4 5.9 2.6e-09 37.0 4.1 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KOS17414.1 - 3.1e-13 49.1 10.4 5.7e-11 41.8 1.7 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KOS17414.1 - 4.1e-12 44.9 3.4 0.00024 20.6 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 KOS17414.1 - 1.1e-08 33.9 1.3 0.00019 20.6 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 KOS17414.1 - 0.00025 20.9 0.1 0.0021 17.9 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain Nup96 PF12110.3 KOS17415.1 - 2e-84 283.1 0.1 3.2e-84 282.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 KOS17415.1 - 3.9e-48 162.8 0.0 6e-48 162.2 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KOS17415.1 - 6.8e-25 87.5 339.9 5.7e-11 42.6 37.3 10.3 3 2 4 7 7 7 3 Nucleoporin FG repeat region ORC6 PF05460.8 KOS17415.1 - 0.31 10.0 1.6 0.63 9.0 1.1 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Thiolase_N PF00108.18 KOS17416.1 - 2.1e-67 226.8 2.2 1.2e-66 224.4 1.5 1.9 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KOS17416.1 - 2.2e-36 123.9 6.4 2.4e-36 123.8 2.5 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KOS17416.1 - 0.054 13.1 3.0 0.4 10.3 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Not1 PF04054.10 KOS17417.1 - 3.7e-83 279.4 0.0 6.7e-83 278.6 0.0 1.3 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KOS17417.1 - 1.2e-25 89.9 0.4 3.4e-25 88.4 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Methyltransf_23 PF13489.1 KOS17418.1 - 9.9e-12 44.8 0.0 2.3e-11 43.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS17418.1 - 0.0001 22.6 0.0 0.061 13.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS17418.1 - 0.00055 20.3 0.0 0.12 12.9 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS17418.1 - 0.0031 18.0 1.2 0.02 15.4 0.3 2.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS17418.1 - 0.0073 16.6 0.0 0.23 11.8 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS17418.1 - 0.0091 15.5 0.0 0.32 10.5 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 KOS17418.1 - 0.14 11.2 0.0 2 7.4 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Seipin PF06775.9 KOS17419.1 - 8.3e-48 162.5 0.2 1e-47 162.2 0.1 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) FCH PF00611.18 KOS17420.1 - 5e-23 81.1 0.7 2.9e-22 78.6 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF922 PF06037.6 KOS17420.1 - 0.12 11.6 7.4 0.04 13.2 0.5 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF922) Syntaxin PF00804.20 KOS17420.1 - 0.2 11.8 5.8 1.3 9.2 4.0 2.3 1 1 0 1 1 1 0 Syntaxin Bap31 PF05529.7 KOS17420.1 - 2.9 7.3 11.2 0.37 10.2 0.2 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Streptin-Immun PF11083.3 KOS17420.1 - 3.4 7.7 7.9 11 6.1 0.1 3.2 3 1 1 4 4 4 0 Lantibiotic streptin immunity protein PADR1 PF08063.7 KOS17421.1 - 0.11 11.9 4.5 0.063 12.6 1.2 1.8 1 1 1 2 2 2 0 PADR1 (NUC008) domain TILa PF12714.2 KOS17421.1 - 0.15 11.8 6.7 0.78 9.5 2.2 2.1 1 1 1 2 2 2 0 TILa domain NTF2 PF02136.15 KOS17423.1 - 6.3e-09 36.2 0.0 7.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain HAD_2 PF13419.1 KOS17424.1 - 6.4e-07 29.7 0.4 0.48 10.6 0.0 3.3 3 0 0 3 3 3 3 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KOS17424.1 - 4.3e-06 26.3 0.1 8.7e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like VHS PF00790.14 KOS17425.1 - 1.9e-30 105.3 0.0 2.3e-15 56.4 0.0 2.6 2 0 0 2 2 2 2 VHS domain SH3_9 PF14604.1 KOS17425.1 - 2e-16 59.2 0.2 3.7e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KOS17425.1 - 2.6e-15 55.5 0.0 4.9e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KOS17425.1 - 5.2e-15 54.6 0.0 9.8e-15 53.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 KOS17425.1 - 0.023 14.6 1.0 0.049 13.5 0.7 1.5 1 0 0 1 1 1 0 GAT domain TIR PF01582.15 KOS17425.1 - 0.17 11.3 0.4 0.41 10.0 0.3 1.6 1 0 0 1 1 1 0 TIR domain UIM PF02809.15 KOS17425.1 - 0.19 11.3 4.8 0.5 10.0 3.4 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif SNF2_N PF00176.18 KOS17426.1 - 5.8e-75 251.8 0.3 1.2e-74 250.7 0.2 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS17426.1 - 3.3e-12 46.0 0.0 4.9e-11 42.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS17426.1 - 1.6e-05 24.4 0.0 3.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KOS17426.1 - 0.00054 19.8 0.0 0.0017 18.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Serglycin PF04360.7 KOS17426.1 - 0.023 14.4 2.6 0.06 13.0 1.8 1.7 1 0 0 1 1 1 0 Serglycin DEAD_2 PF06733.10 KOS17426.1 - 0.033 13.5 0.0 0.092 12.1 0.0 1.7 2 0 0 2 2 2 0 DEAD_2 GTP-bdg_N PF13167.1 KOS17426.1 - 0.075 13.1 0.0 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 GTP-binding GTPase N-terminal SMC_N PF02463.14 KOS17427.1 - 1.7e-60 204.0 0.0 5.6e-60 202.3 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KOS17427.1 - 6.9e-26 90.5 0.0 3.3e-25 88.3 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KOS17427.1 - 2.1e-14 54.3 11.0 2.1e-14 54.3 7.6 6.3 3 2 1 4 4 2 1 AAA domain AAA_21 PF13304.1 KOS17427.1 - 6.5e-11 42.7 2.3 0.00014 21.9 0.4 2.8 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KOS17427.1 - 5.1e-08 32.3 0.0 1.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KOS17427.1 - 2.3e-06 27.0 25.6 0.00059 19.1 0.4 5.1 4 1 1 5 5 5 4 Reovirus sigma C capsid protein Tropomyosin PF00261.15 KOS17427.1 - 0.0043 16.1 24.1 0.0043 16.1 16.7 6.9 3 2 2 5 5 5 3 Tropomyosin SbcCD_C PF13558.1 KOS17427.1 - 0.0061 16.4 0.0 0.026 14.4 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 KOS17427.1 - 0.0099 14.3 94.1 0.11 10.8 17.3 6.2 4 2 2 6 6 6 4 AAA domain NPV_P10 PF05531.7 KOS17427.1 - 0.79 10.0 41.6 0.65 10.2 3.4 8.9 7 2 1 8 8 8 0 Nucleopolyhedrovirus P10 protein DASH_Dam1 PF08653.5 KOS17427.1 - 1.6 8.5 6.4 61 3.4 0.1 5.2 6 0 0 6 6 6 0 DASH complex subunit Dam1 DUF1664 PF07889.7 KOS17427.1 - 3.6 7.3 54.4 1.9 8.3 3.6 7.6 5 2 2 7 7 7 0 Protein of unknown function (DUF1664) Fork_head PF00250.13 KOS17428.1 - 2.5e-14 53.0 0.2 4.7e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Fork head domain FAD_binding_7 PF03441.9 KOS17429.1 - 2.9e-101 338.3 0.0 4.4e-101 337.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KOS17429.1 - 1.9e-38 131.8 0.0 3e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Cofilin_ADF PF00241.15 KOS17430.1 - 1.6e-10 40.9 0.0 1.9e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Lipase_GDSL_2 PF13472.1 KOS17430.1 - 0.13 12.3 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Nipped-B_C PF12830.2 KOS17431.1 - 7.1e-46 156.2 0.6 5.3e-45 153.3 0.1 2.5 2 1 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KOS17431.1 - 1.4e-10 40.8 1.4 1.4e-10 40.8 1.0 2.4 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KOS17431.1 - 1.1e-05 25.1 1.5 0.036 14.1 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 KOS17431.1 - 0.0016 18.3 2.0 0.025 14.4 0.0 3.6 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KOS17431.1 - 0.056 13.9 1.6 4.2 7.9 0.0 4.4 2 1 1 3 3 3 0 HEAT-like repeat TFIIS_C PF01096.13 KOS17432.1 - 4.7e-13 48.5 1.1 4.7e-13 48.5 0.8 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) zinc_ribbon_2 PF13240.1 KOS17432.1 - 0.00031 20.1 12.1 0.61 9.6 0.1 3.9 4 0 0 4 4 4 3 zinc-ribbon domain RNA_POL_M_15KD PF02150.11 KOS17432.1 - 0.0028 17.3 2.5 0.0028 17.3 1.7 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 KOS17432.1 - 0.0092 15.7 7.0 0.2 11.5 1.1 2.6 3 0 0 3 3 3 2 Double zinc ribbon DUF523 PF04463.7 KOS17432.1 - 0.03 14.0 0.2 0.038 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF523) TF_Zn_Ribbon PF08271.7 KOS17432.1 - 0.032 13.5 6.8 3.2 7.1 0.0 3.4 3 0 0 3 3 3 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 KOS17432.1 - 0.055 12.6 12.7 0.77 9.0 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain C1_1 PF00130.17 KOS17432.1 - 0.069 12.8 0.7 0.069 12.8 0.5 2.1 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Lar_restr_allev PF14354.1 KOS17432.1 - 0.076 13.3 0.2 0.076 13.3 0.1 3.1 2 1 0 2 2 2 0 Restriction alleviation protein Lar Zn_ribbon_recom PF13408.1 KOS17432.1 - 0.32 11.2 10.7 12 6.1 1.5 3.3 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-ISL3 PF14690.1 KOS17432.1 - 0.33 11.0 3.9 4.4 7.4 0.1 3.0 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF164 PF02591.10 KOS17432.1 - 0.64 9.8 4.7 24 4.8 0.1 3.3 3 0 0 3 3 3 0 Putative zinc ribbon domain IBR PF01485.16 KOS17432.1 - 0.79 9.6 9.1 0.23 11.3 0.5 2.6 2 1 0 2 2 2 0 IBR domain NOB1_Zn_bind PF08772.6 KOS17432.1 - 0.87 9.4 7.5 1.8 8.4 0.3 3.0 3 1 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like CpXC PF14353.1 KOS17432.1 - 0.93 9.4 3.5 1.4 8.8 0.1 2.2 1 1 1 2 2 2 0 CpXC protein Ribosomal_S27e PF01667.12 KOS17432.1 - 2.3 7.8 9.0 11 5.6 0.3 2.9 2 2 0 2 2 2 0 Ribosomal protein S27 Na_Ca_ex PF01699.19 KOS17433.1 - 2.9e-47 159.7 28.4 1.2e-23 83.2 7.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3608 PF12257.3 KOS17434.1 - 4.4e-69 232.4 0.0 8.4e-69 231.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) FNIP_N PF14636.1 KOS17435.1 - 1.1e-24 87.3 2.8 4e-24 85.5 0.0 3.1 2 1 0 2 2 2 1 Folliculin-interacting protein N-terminus Abhydrolase_6 PF12697.2 KOS17436.1 - 7.1e-24 84.9 1.1 1.3e-23 84.1 0.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS17436.1 - 6.9e-19 68.3 0.0 2.3e-18 66.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS17436.1 - 1.4e-13 50.8 0.3 6.6e-13 48.6 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KOS17436.1 - 0.014 15.0 0.1 0.44 10.2 0.1 2.2 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.15 KOS17436.1 - 0.037 14.2 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Pro_CA PF00484.14 KOS17436.1 - 0.067 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Carbonic anhydrase Ser_hydrolase PF06821.8 KOS17436.1 - 0.082 12.5 0.0 5.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase Lipase_3 PF01764.20 KOS17436.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Ndr PF03096.9 KOS17436.1 - 0.11 10.9 0.0 0.19 10.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family TerY-C PF15616.1 KOS17437.1 - 0.34 10.8 3.5 1.4 8.8 2.5 1.9 1 1 0 1 1 1 0 TerY-C metal binding domain Glyco_hydro_47 PF01532.15 KOS17439.1 - 2.5e-162 540.6 0.0 3e-162 540.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Fig1 PF12351.3 KOS17440.1 - 3.1e-56 190.1 4.6 3.1e-56 190.1 3.2 2.1 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 KOS17440.1 - 1.7e-08 34.3 6.6 2.7e-08 33.6 4.6 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 KOS17440.1 - 0.00019 20.4 6.8 0.00019 20.4 4.7 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 KOS17440.1 - 1 9.5 8.2 0.88 9.8 0.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF202) ODV-E18 PF10717.4 KOS17440.1 - 1.3 8.5 13.5 0.15 11.5 2.4 3.1 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Cupin_2 PF07883.6 KOS17441.1 - 1.8e-06 27.3 0.0 3.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain RINT1_TIP1 PF04437.8 KOS17442.1 - 4e-88 296.1 0.0 6.1e-88 295.5 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DUF4164 PF13747.1 KOS17442.1 - 0.1 12.7 10.2 2.4 8.3 3.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Mito_carr PF00153.22 KOS17443.1 - 1.4e-59 197.7 5.3 1.1e-20 73.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SR-25 PF10500.4 KOS17443.1 - 1.4 8.3 7.1 2.1 7.7 4.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sec34 PF04136.10 KOS17444.1 - 6.7e-28 97.3 0.4 1.3e-27 96.4 0.3 1.4 1 0 0 1 1 1 1 Sec34-like family RseA_N PF03872.8 KOS17444.1 - 0.08 13.2 0.3 0.4 11.0 0.2 2.2 1 0 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain RCC1 PF00415.13 KOS17445.1 - 9.5e-24 83.3 10.3 1.5e-05 25.1 0.0 7.3 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KOS17445.1 - 1.6e-11 43.5 22.8 1.9e-07 30.4 0.0 7.2 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Y_phosphatase PF00102.22 KOS17446.1 - 1.3e-45 155.5 0.0 2.5e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KOS17446.1 - 2.8e-06 27.4 0.1 1.4e-05 25.2 0.0 2.2 3 0 0 3 3 3 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KOS17446.1 - 0.0089 16.2 0.8 0.048 13.9 0.0 2.4 2 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 KOS17446.1 - 0.021 14.4 0.1 0.075 12.6 0.0 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain DeoC PF01791.4 KOS17447.1 - 5.5e-29 101.1 0.0 7.1e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase Glu_synthase PF01645.12 KOS17447.1 - 0.016 14.1 0.1 0.027 13.4 0.1 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase Sterol_MT_C PF08498.5 KOS17447.1 - 0.035 14.0 0.5 0.66 9.9 0.0 2.3 2 0 0 2 2 2 0 Sterol methyltransferase C-terminal FMN_dh PF01070.13 KOS17447.1 - 0.061 12.1 0.2 0.061 12.1 0.1 1.6 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DHO_dh PF01180.16 KOS17447.1 - 0.075 11.9 0.1 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase AFG1_ATPase PF03969.11 KOS17448.1 - 6.1e-81 272.0 0.3 4.5e-76 256.0 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase Sigma54_activ_2 PF14532.1 KOS17448.1 - 0.035 14.1 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain POC1 PF10450.4 KOS17448.1 - 0.073 11.8 0.2 0.17 10.5 0.1 1.5 1 1 0 1 1 1 0 POC1 chaperone SH3_9 PF14604.1 KOS17449.1 - 7.8e-06 25.3 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KOS17449.1 - 0.0056 16.0 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KOS17449.1 - 0.071 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain Mito_carr PF00153.22 KOS17450.1 - 9.1e-58 191.9 4.5 1.1e-19 69.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cation_efflux PF01545.16 KOS17451.1 - 5.6e-56 189.6 0.6 7.9e-56 189.2 0.4 1.2 1 0 0 1 1 1 1 Cation efflux family COX15-CtaA PF02628.10 KOS17451.1 - 0.023 13.5 2.3 0.036 12.9 1.6 1.3 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Spt5_N PF11942.3 KOS17451.1 - 0.051 14.1 5.4 0.11 13.1 3.7 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.9 KOS17451.1 - 0.34 8.9 4.0 0.54 8.2 2.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Glyco_trans_1_4 PF13692.1 KOS17452.1 - 1.2e-24 87.0 0.3 4.8e-24 85.0 0.1 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KOS17452.1 - 0.0035 17.5 0.0 0.0073 16.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 UQ_con PF00179.21 KOS17453.1 - 3.3e-36 123.7 0.0 3.9e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS17453.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 KOS17453.1 - 0.081 12.8 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 RWD domain SR-25 PF10500.4 KOS17454.1 - 1.2 8.6 8.5 1.8 7.9 5.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIIC_delta PF12657.2 KOS17455.1 - 1.4e-17 63.9 6.0 7.8e-17 61.5 4.2 2.1 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 KOS17455.1 - 0.00044 20.1 0.3 0.001 18.9 0.2 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Peptidase_C13 PF01650.13 KOS17456.1 - 2.5e-40 138.4 0.1 3.3e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family His_Phos_1 PF00300.17 KOS17457.1 - 1.1e-08 35.2 0.1 8.1e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Ribosomal_60s PF00428.14 KOS17457.1 - 0.18 12.2 6.4 0.5 10.7 4.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.5 KOS17457.1 - 0.51 10.6 17.1 0.4 10.9 5.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Microtub_assoc PF07989.6 KOS17458.1 - 5.4e-17 61.3 6.4 5.4e-17 61.3 4.5 7.9 7 1 2 9 9 9 1 Microtubule associated Mto2_bdg PF12808.2 KOS17458.1 - 1.9e-11 43.9 11.6 1.9e-11 43.9 8.0 12.8 12 2 2 14 14 14 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 KOS17458.1 - 0.13 11.3 33.7 0.31 10.1 1.2 6.8 4 1 2 7 7 7 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 KOS17458.1 - 9.5 6.5 28.9 0.38 11.0 0.2 7.0 5 1 1 7 7 7 0 Nucleopolyhedrovirus P10 protein PMSR PF01625.16 KOS17459.1 - 2.3e-57 193.2 0.1 2.7e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Pkinase PF00069.20 KOS17460.1 - 6.6e-71 238.4 0.0 8.4e-71 238.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17460.1 - 7.6e-32 110.3 0.0 1e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KOS17460.1 - 2e-10 41.0 2.8 5.8e-10 39.5 2.0 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KOS17460.1 - 0.0043 16.0 0.0 0.0087 15.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KOS17460.1 - 0.17 10.9 0.0 0.38 9.7 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_76 PF03663.9 KOS17461.1 - 1.4e-22 80.6 7.0 4.4e-22 78.9 2.0 3.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 76 PALP PF00291.20 KOS17462.1 - 2.3e-70 237.2 0.1 3.6e-70 236.6 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KOS17462.1 - 1.6e-37 127.0 0.0 1.8e-17 62.6 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DUF2404 PF10296.4 KOS17463.1 - 0.00076 19.5 0.0 0.0088 16.1 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Aminotran_1_2 PF00155.16 KOS17464.1 - 2.9e-82 276.5 0.0 4.1e-82 276.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KOS17464.1 - 5.6e-05 21.5 0.0 9.3e-05 20.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KOS17464.1 - 8.4e-05 21.4 0.0 0.00014 20.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KOS17464.1 - 0.024 13.6 1.3 0.046 12.7 0.1 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family SNF2_N PF00176.18 KOS17465.1 - 2.2e-26 92.3 0.0 4.7e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS17465.1 - 1.1e-16 60.4 0.3 3.3e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain MFS_1 PF07690.11 KOS17466.1 - 7.7e-31 107.0 27.3 7.7e-31 107.0 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nop PF01798.13 KOS17467.1 - 3e-51 172.6 0.3 6.4e-51 171.5 0.2 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOP5NT PF08156.8 KOS17467.1 - 1e-20 73.6 0.3 1e-20 73.6 0.2 2.9 3 1 0 3 3 3 1 NOP5NT (NUC127) domain NOSIC PF08060.8 KOS17467.1 - 2e-20 72.3 0.0 3.4e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain Nucleo_P87 PF07267.6 KOS17467.1 - 1.1 7.8 11.7 1.8 7.1 8.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 KOS17467.1 - 3 5.7 16.7 4.3 5.2 11.6 1.3 1 0 0 1 1 1 0 CDC45-like protein ELYS PF13934.1 KOS17469.1 - 3.1e-58 197.1 0.1 3.7e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly EBP PF05241.7 KOS17470.1 - 2.8e-63 212.4 12.9 3.4e-63 212.1 9.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein MFS_1 PF07690.11 KOS17471.1 - 1.5e-09 37.0 41.2 1.8e-08 33.4 29.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KOS17471.1 - 4.5e-09 36.0 7.0 4.5e-09 36.0 4.9 2.4 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 Hist_deacetyl PF00850.14 KOS17472.1 - 6.9e-80 268.6 0.0 6.9e-80 268.6 0.0 1.8 2 0 0 2 2 2 1 Histone deacetylase domain MFS_1 PF07690.11 KOS17473.1 - 3.2e-30 105.0 26.3 1.3e-23 83.2 5.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS17473.1 - 4.5e-10 38.6 3.4 4.5e-10 38.6 2.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KOS17473.1 - 0.001 17.5 1.9 0.001 17.5 1.3 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KOS17473.1 - 0.0093 14.2 0.3 0.014 13.6 0.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-H2C2 PF09337.5 KOS17474.1 - 1.9e-20 71.9 7.7 4.4e-20 70.8 5.3 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 KOS17474.1 - 0.00051 20.0 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KOS17474.1 - 0.0062 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KOS17474.1 - 0.091 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein PAT1 PF09770.4 KOS17474.1 - 1.7 6.7 15.6 2.2 6.3 10.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.11 KOS17474.1 - 4.3 7.1 4.6 7.2 6.4 3.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_S2 PF00318.15 KOS17475.1 - 7.8e-50 169.0 0.0 3.6e-49 166.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S2 DUF2407_C PF13373.1 KOS17475.1 - 0.086 12.7 1.3 0.17 11.8 0.9 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain Mucin PF01456.12 KOS17475.1 - 5.1 6.8 29.5 0.6 9.8 16.7 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.7 KOS17475.1 - 6.5 4.3 6.3 9 3.9 4.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein XFP_N PF09364.5 KOS17476.1 - 2.8e-175 582.4 0.0 3.7e-175 581.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 KOS17476.1 - 2.6e-83 277.9 0.0 4.7e-83 277.1 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 KOS17476.1 - 8.4e-78 260.4 0.0 1.3e-77 259.8 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain DUF2962 PF11176.3 KOS17476.1 - 0.024 14.1 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) Cpn60_TCP1 PF00118.19 KOS17477.1 - 6e-143 476.9 4.6 6.9e-143 476.7 3.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family 2-oxoacid_dh PF00198.18 KOS17478.1 - 1.1e-79 266.9 0.0 1.8e-79 266.2 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KOS17478.1 - 2.4e-16 59.1 2.7 4.8e-16 58.1 1.8 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF3614 PF12267.3 KOS17478.1 - 0.017 15.4 2.3 0.19 11.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) HlyD_2 PF12700.2 KOS17478.1 - 0.02 14.0 9.6 0.059 12.5 4.4 2.5 1 1 1 2 2 2 0 HlyD family secretion protein RR_TM4-6 PF06459.7 KOS17478.1 - 2 8.2 11.0 2.8 7.7 7.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-MYND PF01753.13 KOS17479.1 - 5.4e-12 45.3 16.0 1.1e-11 44.4 11.1 1.5 1 0 0 1 1 1 1 MYND finger DUF4470 PF14737.1 KOS17479.1 - 8.2e-11 41.5 0.2 5.8e-05 22.7 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4470) CBS PF00571.23 KOS17480.1 - 1.4e-38 130.3 15.5 4.2e-10 39.2 0.0 5.9 6 0 0 6 6 6 4 CBS domain PB1 PF00564.19 KOS17480.1 - 5.8e-08 32.2 0.0 1.4e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Myc_N PF01056.13 KOS17480.1 - 0.093 11.8 8.3 0.24 10.5 2.4 2.3 2 0 0 2 2 2 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 KOS17480.1 - 0.13 12.4 8.9 2.3 8.5 0.1 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Prothymosin PF03247.9 KOS17480.1 - 0.33 11.1 20.7 0.26 11.4 4.7 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family FAM176 PF14851.1 KOS17480.1 - 1.7 8.3 8.5 8.5 6.0 0.4 2.9 3 0 0 3 3 3 0 FAM176 family PBP1_TM PF14812.1 KOS17480.1 - 1.9 8.8 12.8 3.1 8.1 2.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2 PF00096.21 KOS17481.1 - 1.6e-09 37.5 10.0 2.8e-05 24.1 3.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KOS17481.1 - 2.1e-08 34.0 10.4 0.00082 19.5 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KOS17481.1 - 0.00027 21.0 9.1 0.17 12.2 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger C1_4 PF07975.7 KOS17481.1 - 0.078 13.0 4.2 0.15 12.1 2.9 1.4 1 0 0 1 1 1 0 TFIIH C1-like domain DUF1395 PF07160.7 KOS17481.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) SprT-like PF10263.4 KOS17481.1 - 0.16 11.5 2.9 0.27 10.8 2.0 1.4 1 1 0 1 1 1 0 SprT-like family zf-met PF12874.2 KOS17481.1 - 1 9.6 6.1 4.9 7.5 1.6 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KOS17481.1 - 6.8 6.9 9.1 27 5.0 2.5 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Cpn60_TCP1 PF00118.19 KOS17482.1 - 1.3e-150 502.2 0.5 1.5e-150 502.0 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PDCD2_C PF04194.8 KOS17483.1 - 5.1e-50 169.2 0.0 1.4e-49 167.8 0.0 1.7 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Herpes_UL32 PF06070.6 KOS17483.1 - 0.0089 14.5 1.0 0.011 14.2 0.7 1.1 1 0 0 1 1 1 1 Herpesvirus large structural phosphoprotein UL32 GTP_EFTU PF00009.22 KOS17484.1 - 6.3e-63 211.6 0.4 9.3e-63 211.0 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KOS17484.1 - 3.6e-37 126.5 0.0 9.4e-37 125.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KOS17484.1 - 4.1e-21 74.6 0.0 1.1e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KOS17484.1 - 3.8e-13 49.3 1.1 9.7e-13 48.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KOS17484.1 - 2.6e-12 46.4 0.0 6.7e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KOS17484.1 - 1.9e-05 24.5 0.2 4.4e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KOS17484.1 - 0.061 12.8 0.3 0.21 11.0 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PAD_M PF08527.5 KOS17484.1 - 0.12 11.7 0.1 0.3 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain Solute_trans_a PF03619.11 KOS17487.1 - 6.1e-106 353.7 9.7 7.3e-106 353.4 6.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Glyco_hydro_92 PF07971.7 KOS17488.1 - 1.8e-135 452.4 0.0 2.3e-135 452.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 zf-C2H2_6 PF13912.1 KOS17489.1 - 0.0037 17.1 0.3 0.0037 17.1 0.2 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger Zn_clus PF00172.13 KOS17489.1 - 0.51 10.2 12.8 0.025 14.5 4.7 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-BED PF02892.10 KOS17489.1 - 1.5 8.6 9.4 0.039 13.7 0.6 2.4 2 0 0 2 2 2 0 BED zinc finger Sec5 PF15469.1 KOS17490.1 - 2.7e-36 124.9 0.3 1.5e-34 119.2 0.0 3.5 4 0 0 4 4 4 1 Exocyst complex component Sec5 Vps51 PF08700.6 KOS17490.1 - 8.5e-05 22.3 3.4 0.0011 18.7 0.1 3.5 3 0 0 3 3 3 1 Vps51/Vps67 Iso_dh PF00180.15 KOS17491.1 - 3.4e-99 332.0 0.1 4.2e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 KOS17491.1 - 0.11 12.4 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Transglut_core PF01841.14 KOS17493.1 - 1.7e-09 37.8 0.0 3.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 KOS17493.1 - 0.044 13.0 0.0 0.46 9.7 0.0 2.3 2 1 0 2 2 2 0 Transglutaminase-like domain MARVEL PF01284.18 KOS17495.1 - 6.8e-05 22.7 11.1 0.00045 20.0 7.6 1.9 1 1 1 2 2 2 1 Membrane-associating domain UPF0104 PF03706.8 KOS17495.1 - 0.015 14.6 2.4 0.019 14.2 1.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) ABC2_membrane PF01061.19 KOS17495.1 - 0.046 12.8 5.4 0.026 13.6 2.1 1.7 2 0 0 2 2 2 0 ABC-2 type transporter TPR_11 PF13414.1 KOS17497.1 - 2.1e-54 181.0 26.5 1e-16 60.3 0.3 6.3 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 KOS17497.1 - 1.8e-41 138.0 22.4 1.4e-07 30.8 0.1 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 KOS17497.1 - 2.4e-33 111.3 19.8 6.2e-05 22.6 0.1 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 KOS17497.1 - 2.3e-19 69.1 8.8 5.5e-11 42.2 0.3 6.1 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 KOS17497.1 - 1.2e-15 56.0 18.9 3.6e-06 26.3 0.3 7.7 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 KOS17497.1 - 1.8e-13 50.7 10.6 0.00088 19.8 0.0 6.4 4 2 2 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 KOS17497.1 - 2.4e-13 49.4 6.7 0.085 13.5 0.0 8.8 4 3 6 10 10 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 KOS17497.1 - 6.6e-13 47.7 1.0 0.021 15.0 0.0 7.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KOS17497.1 - 1.2e-09 37.2 9.2 0.0023 17.5 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 KOS17497.1 - 5.2e-08 32.6 0.1 0.054 13.3 0.0 4.7 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS17497.1 - 5.3e-08 33.0 8.0 0.013 15.8 0.0 5.7 5 1 1 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KOS17497.1 - 5.9e-05 23.1 9.6 0.0051 16.9 1.3 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KOS17497.1 - 0.00042 20.5 12.6 0.15 12.5 0.0 7.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 KOS17497.1 - 0.002 18.0 0.3 1.6 8.7 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KOS17497.1 - 0.0037 16.4 0.2 7.4 5.8 0.0 3.6 3 0 0 3 3 3 0 SHNi-TPR Sec5 PF15469.1 KOS17497.1 - 0.0071 16.0 3.1 0.26 10.9 0.3 3.2 2 1 1 3 3 3 1 Exocyst complex component Sec5 Fis1_TPR_C PF14853.1 KOS17497.1 - 0.036 13.9 0.3 7 6.6 0.0 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.4 KOS17497.1 - 0.55 9.5 0.0 0.55 9.5 0.0 4.7 4 3 1 5 5 5 0 26S proteasome subunit RPN7 TPR_3 PF07720.7 KOS17497.1 - 5.6 6.8 8.7 8.9 6.2 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Gastrin PF00918.12 KOS17497.1 - 5.8 7.7 9.7 1.6 9.5 0.5 3.2 3 0 0 3 3 3 0 Gastrin/cholecystokinin family MIT PF04212.13 KOS17497.1 - 6.7 6.6 23.8 0.87 9.5 0.4 6.5 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain RFX_DNA_binding PF02257.10 KOS17498.1 - 2.6e-29 101.1 0.1 6.2e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain Sporozoite_P67 PF05642.6 KOS17498.1 - 0.24 9.2 3.6 0.39 8.5 2.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 KOS17498.1 - 3.6 7.0 7.8 0.6 9.6 2.5 1.7 2 0 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 KOS17498.1 - 4.9 6.7 5.9 0.81 9.2 1.3 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region AA_kinase PF00696.23 KOS17499.1 - 9.3e-32 110.4 0.0 3e-31 108.8 0.0 1.9 2 1 0 2 2 2 1 Amino acid kinase family ACT PF01842.20 KOS17499.1 - 2e-15 55.8 0.8 4.5e-09 35.6 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 KOS17499.1 - 9.3e-15 53.9 3.3 1.3e-09 37.4 0.1 2.5 2 0 0 2 2 2 2 ACT domain Adaptin_N PF01602.15 KOS17500.1 - 4.1e-80 269.5 0.0 7.3e-80 268.7 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 KOS17500.1 - 0.21 11.7 3.0 50 4.3 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat Cnd1 PF12717.2 KOS17500.1 - 0.83 9.4 4.4 3.3 7.5 0.3 2.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 ECH PF00378.15 KOS17501.1 - 5e-68 228.8 0.0 6.1e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MotA_activ PF09114.5 KOS17501.1 - 0.098 12.4 0.0 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Transcription factor MotA, activation domain DapB_N PF01113.15 KOS17502.1 - 0.00038 20.3 0.0 0.00042 20.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 KOS17502.1 - 0.041 13.8 0.0 0.051 13.5 0.0 1.1 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 KOS17502.1 - 0.052 12.9 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Bax1-I PF01027.15 KOS17503.1 - 7.6e-30 104.0 9.9 1.3e-29 103.3 6.8 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SNF2_N PF00176.18 KOS17504.1 - 5.3e-83 278.2 1.7 5.3e-83 278.2 1.2 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KOS17504.1 - 9.6e-21 73.5 0.1 3.3e-20 71.7 0.1 2.0 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 KOS17504.1 - 1.4e-18 66.4 0.4 1.7e-16 59.8 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 KOS17504.1 - 1e-17 64.0 0.8 1e-17 64.0 0.6 3.8 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 KOS17504.1 - 1.3e-13 50.4 11.3 1.3e-13 50.4 7.9 2.9 2 0 0 2 2 2 1 HSA QLQ PF08880.6 KOS17504.1 - 1.1e-09 37.4 3.7 3.8e-09 35.8 2.6 2.0 1 0 0 1 1 1 1 QLQ DUF167 PF02594.11 KOS17505.1 - 5e-18 64.8 0.0 6.2e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 CP2 PF04516.10 KOS17506.1 - 1.3e-50 171.6 0.1 2e-40 138.3 0.0 2.9 2 1 1 3 3 3 2 CP2 transcription factor Tektin PF03148.9 KOS17506.1 - 0.029 12.9 0.2 0.048 12.2 0.1 1.4 1 0 0 1 1 1 0 Tektin family RPN7 PF10602.4 KOS17506.1 - 0.048 13.0 0.2 0.081 12.2 0.1 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN7 CENP-Q PF13094.1 KOS17506.1 - 0.33 10.9 2.8 0.23 11.4 0.3 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RRN9 PF10680.4 KOS17507.1 - 0.04 13.6 0.5 0.31 10.7 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor DUF2215 PF10225.4 KOS17507.1 - 0.23 10.8 0.7 13 5.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) eIF2A PF08662.6 KOS17508.1 - 3.3e-78 261.8 0.0 1.6e-77 259.6 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KOS17508.1 - 3.5e-05 23.5 0.9 7.8 6.5 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat CDV3 PF15359.1 KOS17508.1 - 0.0016 18.5 0.4 0.0016 18.5 0.3 2.2 2 0 0 2 2 2 1 Carnitine deficiency-associated protein 3 YscJ_FliF_C PF08345.6 KOS17508.1 - 4.9 7.0 7.5 1.1 9.2 0.9 2.2 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal GPP34 PF05719.6 KOS17509.1 - 3.9e-63 213.2 0.1 4.9e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) W2 PF02020.13 KOS17511.1 - 4.7e-17 61.7 0.7 1.1e-16 60.5 0.5 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 KOS17511.1 - 1.5e-11 43.2 11.3 1.5e-07 30.5 1.9 4.2 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 KOS17511.1 - 0.00015 21.1 0.0 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 KOS17511.1 - 0.0022 17.4 0.6 0.0022 17.4 0.4 3.8 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 KOS17511.1 - 0.012 15.6 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF2410 PF10307.4 KOS17512.1 - 2.6e-80 268.4 0.0 3.6e-80 268.0 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) RPAP1_C PF08620.5 KOS17513.1 - 8.7e-29 99.1 0.0 1.5e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KOS17513.1 - 1.7e-14 53.1 4.7 2.6e-14 52.5 3.3 1.3 1 0 0 1 1 1 1 RPAP1-like, N-terminal VHS PF00790.14 KOS17514.1 - 3e-45 153.3 0.0 1.2e-44 151.3 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KOS17514.1 - 8.8e-25 86.6 0.3 3.2e-24 84.8 0.2 2.0 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 KOS17514.1 - 9.8e-16 58.0 0.0 9.8e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 Adaptin C-terminal domain Sec10 PF07393.6 KOS17515.1 - 7.1e-157 523.6 0.0 1.5e-156 522.5 0.0 1.5 1 1 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 KOS17515.1 - 1.4e-06 27.9 0.5 3.7e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KOS17515.1 - 3e-05 23.5 0.0 5.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain SLIDE PF09111.5 KOS17515.1 - 0.062 13.0 1.2 0.15 11.8 0.8 1.5 1 0 0 1 1 1 0 SLIDE Pex14_N PF04695.8 KOS17515.1 - 0.72 9.8 8.8 0.37 10.8 2.2 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pyr_redox_2 PF07992.9 KOS17516.1 - 3.2e-36 125.1 0.0 8.9e-36 123.6 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS17516.1 - 1.9e-14 53.8 0.0 1.1e-11 45.0 0.0 3.3 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KOS17516.1 - 1.1e-11 45.1 0.0 2.4e-05 24.4 0.0 3.4 2 2 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS17516.1 - 0.029 14.4 0.0 10 6.2 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KOS17516.1 - 0.052 13.6 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Trehalase_Ca-bi PF07492.6 KOS17516.1 - 0.18 11.1 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain Frag1 PF10277.4 KOS17517.1 - 3.9e-39 134.3 17.8 4.5e-39 134.1 12.4 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Tetraspannin PF00335.15 KOS17517.1 - 0.00096 18.4 1.9 0.00096 18.4 1.3 1.9 2 0 0 2 2 2 1 Tetraspanin family DUF2207 PF09972.4 KOS17517.1 - 0.0079 14.8 3.1 0.11 11.0 0.0 2.3 1 1 1 2 2 2 2 Predicted membrane protein (DUF2207) NfeD PF01957.13 KOS17517.1 - 0.12 12.4 4.1 5 7.2 0.2 2.7 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding DUF1673 PF07895.6 KOS17517.1 - 1.2 8.6 5.4 7.1 6.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) Cation_efflux PF01545.16 KOS17517.1 - 3.6 6.5 14.3 2.3 7.2 8.8 1.4 1 1 0 1 1 1 0 Cation efflux family TPR_11 PF13414.1 KOS17518.1 - 2.6e-11 42.9 0.5 6.5e-06 25.7 0.0 4.2 2 2 2 4 4 4 2 TPR repeat TPR_19 PF14559.1 KOS17518.1 - 3e-10 40.2 5.4 9.2e-06 25.9 0.0 3.9 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KOS17518.1 - 3.9e-08 32.6 0.5 0.00057 19.5 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KOS17518.1 - 1.1e-07 31.0 0.6 0.0017 17.8 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KOS17518.1 - 3.8e-06 27.0 7.1 0.00087 19.7 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KOS17518.1 - 4.7e-05 23.9 0.2 4.7e-05 23.9 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KOS17518.1 - 6.2e-05 22.4 0.2 0.38 10.6 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KOS17518.1 - 0.0017 18.2 4.7 3.3 7.7 0.1 4.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KOS17518.1 - 0.0018 18.5 2.2 6.8 7.3 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KOS17518.1 - 0.0066 16.5 0.3 0.089 13.0 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS17518.1 - 0.025 14.3 0.1 41 4.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KOS17518.1 - 0.043 13.6 0.2 0.17 11.7 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Arg_repressor PF01316.16 KOS17518.1 - 0.12 11.9 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain TPR_10 PF13374.1 KOS17518.1 - 1.3 9.0 4.5 5.5 7.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Proteasome PF00227.21 KOS17520.1 - 1.2e-53 181.1 0.1 1.8e-53 180.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KOS17520.1 - 1.8e-12 46.3 0.1 1.8e-12 46.3 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature PALP PF00291.20 KOS17521.1 - 1.5e-60 205.0 0.0 1.8e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Band_3_cyto PF07565.8 KOS17522.1 - 0.0016 18.0 7.2 0.027 13.9 3.6 2.1 2 0 0 2 2 2 1 Band 3 cytoplasmic domain Spore_coat_CotO PF14153.1 KOS17522.1 - 0.0018 17.7 7.1 0.0027 17.1 4.9 1.3 1 0 0 1 1 1 1 Spore coat protein CotO Med15 PF09606.5 KOS17522.1 - 0.0055 14.9 9.8 0.0064 14.7 6.8 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal IlvN PF07991.7 KOS17522.1 - 0.0084 15.4 0.9 3.7 6.9 0.0 2.5 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain AIF_C PF14721.1 KOS17522.1 - 0.0099 16.1 3.3 0.027 14.7 2.3 1.7 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term FAM176 PF14851.1 KOS17522.1 - 0.011 15.4 4.3 0.023 14.3 3.0 1.5 1 0 0 1 1 1 0 FAM176 family RNase_H2_suC PF08615.6 KOS17522.1 - 0.036 13.9 0.2 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF1682 PF07946.9 KOS17522.1 - 0.083 11.7 9.8 0.12 11.1 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FliP PF00813.15 KOS17522.1 - 0.09 12.4 0.2 0.17 11.6 0.2 1.4 1 0 0 1 1 1 0 FliP family Usp PF00582.21 KOS17522.1 - 0.14 12.3 1.5 0.36 11.0 1.1 1.7 1 0 0 1 1 1 0 Universal stress protein family Neur_chan_memb PF02932.11 KOS17522.1 - 0.19 11.6 0.5 0.25 11.2 0.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4557 PF15101.1 KOS17522.1 - 0.29 10.9 9.5 0.55 10.0 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ycf1 PF05758.7 KOS17522.1 - 0.35 8.5 5.7 0.48 8.0 3.9 1.2 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 KOS17522.1 - 0.37 10.5 6.4 0.63 9.7 4.4 1.3 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 KOS17522.1 - 0.4 9.3 4.0 0.55 8.8 2.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) PBP1_TM PF14812.1 KOS17522.1 - 0.57 10.5 7.0 1.1 9.6 4.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Prog_receptor PF02161.10 KOS17522.1 - 0.58 8.9 5.1 0.85 8.3 3.6 1.2 1 0 0 1 1 1 0 Progesterone receptor FKBP_N PF01346.13 KOS17522.1 - 0.68 9.9 14.7 1.4 8.9 10.2 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Sporozoite_P67 PF05642.6 KOS17522.1 - 0.73 7.6 4.1 1.1 7.0 2.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3306 PF11748.3 KOS17522.1 - 0.93 10.1 9.7 3.4 8.3 6.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) ATP-synt_E PF05680.7 KOS17522.1 - 1 9.3 10.3 2.6 8.0 7.1 1.6 1 0 0 1 1 1 0 ATP synthase E chain Folate_carrier PF01770.13 KOS17522.1 - 1.3 7.4 2.9 1.9 6.8 2.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier Peptidase_S49_N PF08496.5 KOS17522.1 - 3 7.6 10.2 9.6 5.9 5.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MscS_TM PF12794.2 KOS17522.1 - 3 6.3 7.7 4.6 5.7 5.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Bap31 PF05529.7 KOS17522.1 - 3.2 7.1 10.4 5.8 6.3 7.2 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like SID-1_RNA_chan PF13965.1 KOS17522.1 - 3.8 5.5 4.6 5.1 5.1 3.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Glyco_transf_15 PF01793.11 KOS17522.1 - 3.9 6.3 8.0 5.8 5.7 5.6 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Bd3614-deam PF14439.1 KOS17524.1 - 0.052 13.4 4.7 0.077 12.8 3.2 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase Glypican PF01153.14 KOS17524.1 - 0.22 10.0 2.2 0.25 9.9 1.5 1.0 1 0 0 1 1 1 0 Glypican CH PF00307.26 KOS17525.1 - 2.1e-39 133.8 0.4 2.2e-19 69.4 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KOS17525.1 - 3.8e-29 100.4 1.2 1.2e-27 95.6 0.0 2.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KOS17525.1 - 3.8e-13 48.9 0.8 9.9e-08 31.5 0.0 3.0 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 KOS17525.1 - 3.3e-05 23.4 0.1 0.0029 17.3 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 KOS17525.1 - 0.00023 20.6 0.3 0.016 14.8 0.0 3.1 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 KOS17525.1 - 0.00056 19.0 0.1 0.031 13.5 0.0 2.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KOS17525.1 - 0.00076 19.5 2.0 0.0033 17.5 1.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair Sipho_Gp157 PF05565.6 KOS17525.1 - 0.032 13.8 4.3 0.33 10.5 0.4 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 EMP24_GP25L PF01105.19 KOS17525.1 - 0.041 13.5 0.6 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD EF-hand_like PF09279.6 KOS17525.1 - 0.058 13.4 0.9 0.15 12.0 0.1 2.2 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like FAD-oxidase_C PF02913.14 KOS17526.1 - 6.9e-62 208.9 0.0 1e-61 208.4 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KOS17526.1 - 6.5e-37 126.1 0.5 1.5e-36 124.9 0.4 1.6 1 0 0 1 1 1 1 FAD binding domain Ribosomal_L19 PF01245.15 KOS17527.1 - 3.7e-16 58.9 0.0 8.4e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L19 Ribosomal_S21e PF01249.13 KOS17529.1 - 9.4e-42 140.8 0.1 1e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Slx4 PF09494.5 KOS17530.1 - 2.5e-24 84.8 0.0 3.1e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Slx4 endonuclease DUF2521 PF10730.4 KOS17530.1 - 0.052 13.3 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) Ribosomal_L14 PF00238.14 KOS17531.1 - 1.6e-30 105.3 0.0 1.7e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Cactin_mid PF10312.4 KOS17532.1 - 1.4e-54 184.2 6.3 1.9e-54 183.8 4.4 1.1 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 KOS17532.1 - 5.4e-53 177.8 2.3 5.4e-53 177.8 1.6 1.6 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein dNK PF01712.14 KOS17532.1 - 0.053 13.4 0.1 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase DUF1087 PF06465.8 KOS17532.1 - 0.15 12.0 4.4 0.072 13.0 1.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) QLQ PF08880.6 KOS17532.1 - 0.34 10.3 1.7 8.5 5.8 0.1 2.4 2 0 0 2 2 2 0 QLQ DUF2413 PF10310.4 KOS17533.1 - 6.4e-129 430.6 7.5 1.9e-128 429.0 5.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) Virul_fac_BrkB PF03631.10 KOS17533.1 - 0.0063 15.9 1.9 0.0093 15.3 1.3 1.2 1 0 0 1 1 1 1 Virulence factor BrkB DUF4175 PF13779.1 KOS17533.1 - 0.01 13.6 21.9 0.014 13.1 15.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) Ycf1 PF05758.7 KOS17533.1 - 0.02 12.6 0.7 0.024 12.3 0.5 1.1 1 0 0 1 1 1 0 Ycf1 Gly_rich PF12810.2 KOS17533.1 - 0.028 14.0 9.0 0.046 13.3 6.3 1.2 1 0 0 1 1 1 0 Glycine rich protein DUF775 PF05603.7 KOS17533.1 - 0.043 13.3 6.1 0.082 12.4 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Med15 PF09606.5 KOS17533.1 - 0.16 10.1 28.8 0.23 9.5 20.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex16 PF08610.5 KOS17533.1 - 0.2 10.6 5.7 0.35 9.8 4.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Suf PF05843.9 KOS17533.1 - 0.32 10.6 10.6 0.51 10.0 7.4 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 KOS17533.1 - 0.38 10.0 6.9 0.63 9.3 4.8 1.4 1 0 0 1 1 1 0 Spt20 family UPF0560 PF10577.4 KOS17533.1 - 0.43 8.7 11.0 0.57 8.3 7.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Glyco_transf_15 PF01793.11 KOS17533.1 - 0.69 8.7 4.0 1 8.2 2.8 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase TFIIA PF03153.8 KOS17533.1 - 0.82 9.4 21.9 1.5 8.6 15.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4557 PF15101.1 KOS17533.1 - 1.1 9.1 10.9 2.2 8.0 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FimP PF09766.4 KOS17533.1 - 1.1 8.2 15.8 1.9 7.4 10.9 1.3 1 0 0 1 1 1 0 Fms-interacting protein Paf1 PF03985.8 KOS17533.1 - 1.9 7.1 9.1 2.5 6.7 6.3 1.1 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.7 KOS17533.1 - 4.8 7.0 11.9 8.1 6.2 8.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BAF1_ABF1 PF04684.8 KOS17533.1 - 7.2 5.3 31.3 5.6 5.6 0.5 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Hid1 PF12722.2 KOS17533.1 - 8.4 3.9 7.1 11 3.6 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Clat_adaptor_s PF01217.15 KOS17535.1 - 9.3e-58 193.9 1.6 1e-57 193.8 1.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ist1 PF03398.9 KOS17536.1 - 1.5e-60 203.3 0.1 1.9e-60 203.0 0.1 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway LCM PF04072.9 KOS17537.1 - 2.7e-18 66.1 0.0 7.5e-18 64.7 0.0 1.7 2 1 0 2 2 2 1 Leucine carboxyl methyltransferase TFIID-18kDa PF02269.11 KOS17538.1 - 6e-13 48.4 2.7 7.4e-12 44.9 0.2 2.9 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.13 KOS17538.1 - 0.039 13.1 0.6 0.059 12.5 0.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Kinesin PF00225.18 KOS17539.1 - 7.7e-113 376.5 0.3 2e-112 375.2 0.2 1.7 1 0 0 1 1 1 1 Kinesin motor domain T2SF PF00482.18 KOS17539.1 - 0.13 12.1 1.1 0.86 9.5 0.8 2.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F CENP-F_leu_zip PF10473.4 KOS17539.1 - 3.6 7.4 66.4 1.2 9.0 15.0 5.0 4 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2427 PF10348.4 KOS17540.1 - 0.17 11.5 0.0 0.17 11.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) Thiolase_N PF00108.18 KOS17541.1 - 3e-86 288.6 1.4 4.6e-86 288.0 1.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KOS17541.1 - 1e-38 131.4 1.4 1e-38 131.4 1.0 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KOS17541.1 - 0.00019 20.9 0.6 0.00063 19.2 0.4 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain UQ_con PF00179.21 KOS17542.1 - 7.6e-52 174.4 0.1 8.6e-52 174.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS17542.1 - 2.2e-06 27.4 0.0 2.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KOS17542.1 - 0.0073 16.1 0.2 0.022 14.6 0.1 1.6 1 1 0 1 1 1 1 RWD domain Pkinase PF00069.20 KOS17543.1 - 1e-28 100.2 0.0 1.2e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17543.1 - 2.7e-12 46.3 0.0 3.6e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS17543.1 - 6.9e-06 25.9 1.0 5.3e-05 23.0 0.3 2.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family PDZ_1 PF12812.2 KOS17544.1 - 2.6e-54 181.0 0.1 3.3e-34 116.6 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 KOS17544.1 - 2.7e-14 52.7 0.1 9e-06 25.5 0.0 4.4 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 KOS17544.1 - 9.3e-14 51.4 0.0 2e-12 47.1 0.1 2.7 3 1 0 3 3 3 1 Trypsin-like peptidase domain PDZ PF00595.19 KOS17544.1 - 1.9e-09 37.5 0.0 2.2e-05 24.5 0.0 3.9 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 KOS17544.1 - 6.4e-05 22.6 0.0 0.00017 21.2 0.0 1.7 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 KOS17544.1 - 0.0053 16.5 0.1 0.19 11.5 0.0 2.9 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.4 KOS17544.1 - 0.19 10.0 0.4 0.84 7.9 0.0 1.8 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S7 PF00949.16 KOS17544.1 - 0.2 11.0 0.4 0.43 9.9 0.3 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S49_N PF08496.5 KOS17545.1 - 0.029 14.1 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Nitroreductase PF00881.19 KOS17546.1 - 7.9e-18 64.8 0.0 9.6e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family CTDII PF01556.13 KOS17547.1 - 5e-27 93.6 0.4 9.6e-21 73.4 0.0 3.1 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KOS17547.1 - 4e-25 87.3 2.6 7.9e-25 86.3 1.8 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KOS17547.1 - 8.2e-11 41.8 18.3 1.5e-10 40.9 12.7 1.4 1 0 0 1 1 1 1 DnaJ central domain SAP30_Sin3_bdg PF13867.1 KOS17548.1 - 1.2e-11 44.3 0.2 3.2e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DEAD PF00270.24 KOS17549.1 - 5.7e-44 149.5 0.0 1.5e-43 148.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS17549.1 - 2.3e-22 78.6 0.1 1.4e-21 76.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 KOS17549.1 - 5e-20 71.0 1.4 1.4e-19 69.6 1.0 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 KOS17549.1 - 0.0066 16.2 0.0 0.022 14.6 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaJ PF00226.26 KOS17550.1 - 8.8e-14 51.0 0.3 8.8e-14 51.0 0.2 2.9 4 1 0 4 4 4 1 DnaJ domain DUF3512 PF12024.3 KOS17550.1 - 0.015 14.6 4.9 0.016 14.5 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) HSP20 PF00011.16 KOS17550.1 - 0.037 13.9 2.5 5.2 7.0 1.8 2.6 2 1 0 2 2 2 0 Hsp20/alpha crystallin family Pex2_Pex12 PF04757.9 KOS17551.1 - 3.1e-57 193.6 4.3 4.2e-57 193.2 3.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 KOS17551.1 - 9.6e-06 25.5 2.9 1.6e-05 24.7 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS17551.1 - 0.0012 18.6 3.0 0.002 17.9 2.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KOS17551.1 - 0.0013 18.5 2.4 0.0023 17.7 1.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING RIC3 PF15361.1 KOS17551.1 - 0.036 14.3 0.9 0.06 13.5 0.6 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 zf-C3HC4 PF00097.20 KOS17551.1 - 0.076 12.6 2.0 0.13 11.8 1.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cut8_M PF14483.1 KOS17551.1 - 0.093 12.5 0.6 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Cut8 dimerisation domain zf-C3HC4_3 PF13920.1 KOS17551.1 - 0.17 11.6 1.6 0.3 10.7 1.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WSC PF01822.14 KOS17552.1 - 9e-11 41.5 8.0 9e-11 41.5 5.6 2.2 3 0 0 3 3 3 1 WSC domain Glyco_hydro_16 PF00722.16 KOS17552.1 - 3.4e-06 26.4 0.1 8e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 cNMP_binding PF00027.24 KOS17553.1 - 1.7e-35 120.7 0.0 3.3e-19 68.4 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 KOS17553.1 - 1.6e-12 46.0 9.5 0.024 14.6 0.0 8.1 9 1 0 9 9 9 3 Leucine Rich repeat F-box PF00646.28 KOS17553.1 - 3.2e-08 33.0 0.6 3.2e-08 33.0 0.4 2.6 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.2 KOS17553.1 - 2.4e-06 27.0 0.0 0.56 9.8 0.0 4.0 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KOS17553.1 - 2.7e-05 23.7 2.4 4.1e-05 23.2 0.3 2.4 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 KOS17553.1 - 3.7e-05 23.3 3.2 0.022 14.4 0.2 3.1 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KOS17553.1 - 0.00017 21.1 6.4 3.8 7.9 0.1 6.9 7 2 1 8 8 8 1 Leucine Rich Repeat Cupin_3 PF05899.7 KOS17553.1 - 0.023 14.0 0.1 2.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) LRR_7 PF13504.1 KOS17553.1 - 0.035 14.2 7.2 33 5.3 0.1 5.9 5 0 0 5 5 5 0 Leucine rich repeat Noc2 PF03715.8 KOS17554.1 - 2e-116 388.0 0.0 3.4e-116 387.2 0.0 1.4 1 0 0 1 1 1 1 Noc2p family TFIIA PF03153.8 KOS17554.1 - 3.8e-05 23.7 6.8 3.8e-05 23.7 4.7 3.2 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit CobN-Mg_chel PF02514.11 KOS17554.1 - 0.0041 14.6 5.4 0.0074 13.7 3.8 1.3 1 0 0 1 1 1 1 CobN/Magnesium Chelatase Cep57_CLD_2 PF14197.1 KOS17555.1 - 3e-27 94.3 60.6 9.2e-14 51.1 5.1 6.4 3 1 1 4 4 4 2 Centrosome localisation domain of PPC89 Cep57_MT_bd PF06657.8 KOS17555.1 - 3.1e-24 84.7 0.6 3.1e-24 84.7 0.4 6.3 4 2 3 7 7 7 1 Centrosome microtubule-binding domain of Cep57 WEMBL PF05701.6 KOS17555.1 - 4e-08 32.1 36.4 1.4e-05 23.7 3.8 2.7 1 1 1 2 2 2 2 Weak chloroplast movement under blue light APG6 PF04111.7 KOS17555.1 - 0.00036 19.6 51.7 0.0014 17.7 8.4 4.2 2 1 2 4 4 4 2 Autophagy protein Apg6 CCDC155 PF14662.1 KOS17555.1 - 0.00075 19.1 14.3 0.00075 19.1 9.9 4.6 2 1 2 4 4 4 2 Coiled-coil region of CCDC155 Myosin_tail_1 PF01576.14 KOS17555.1 - 0.001 16.9 57.3 0.0033 15.2 11.4 2.8 2 1 1 3 3 3 2 Myosin tail TSC22 PF01166.13 KOS17555.1 - 0.0013 18.6 23.3 0.15 12.0 1.0 6.0 3 2 1 5 5 5 2 TSC-22/dip/bun family DUF904 PF06005.7 KOS17555.1 - 0.0019 18.4 6.3 0.0019 18.4 4.4 8.0 2 1 5 7 7 7 3 Protein of unknown function (DUF904) HALZ PF02183.13 KOS17555.1 - 0.0042 16.7 57.6 0.098 12.3 1.1 9.4 7 2 3 10 10 10 4 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.4 KOS17555.1 - 0.0048 16.7 55.6 0.036 13.9 10.4 4.5 2 1 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 KOS17555.1 - 0.0064 16.8 45.9 0.066 13.5 2.8 7.2 3 3 3 6 6 6 2 Protein of unknown function (DUF972) IncA PF04156.9 KOS17555.1 - 0.0074 15.9 63.3 0.022 14.3 10.2 4.9 2 1 2 4 4 3 2 IncA protein Filament PF00038.16 KOS17555.1 - 0.072 12.5 49.2 0.025 14.0 9.7 3.6 2 1 3 5 5 5 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 KOS17555.1 - 0.1 12.3 46.8 0.042 13.6 10.0 4.9 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein DUF730 PF05325.6 KOS17555.1 - 0.23 11.2 6.0 39 4.0 0.1 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF730) Reo_sigmaC PF04582.7 KOS17555.1 - 0.85 8.7 15.4 2.2 7.3 0.3 3.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DivIC PF04977.10 KOS17555.1 - 1.2 8.6 49.1 0.34 10.4 1.5 7.1 3 2 3 7 7 6 0 Septum formation initiator HAP1_N PF04849.8 KOS17555.1 - 1.6 7.5 54.8 1.8 7.4 0.5 5.2 2 1 3 5 5 5 0 HAP1 N-terminal conserved region DUF4618 PF15397.1 KOS17555.1 - 1.6 7.9 33.4 7.8 5.7 0.2 4.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4618) Kinetocho_Slk19 PF12709.2 KOS17555.1 - 3 7.9 34.9 0.15 12.1 2.1 6.7 3 1 3 6 6 6 0 Central kinetochore-associated bZIP_1 PF00170.16 KOS17555.1 - 3.1 7.8 37.6 0.35 10.8 1.4 7.4 3 2 4 7 7 7 0 bZIP transcription factor CALCOCO1 PF07888.6 KOS17555.1 - 3.5 5.8 44.7 0.16 10.2 6.3 3.6 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1664 PF07889.7 KOS17555.1 - 8.2 6.2 25.2 8.2 6.2 2.9 5.2 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) RNase_T PF00929.19 KOS17557.1 - 3.2e-13 50.2 0.0 2.6e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Exonuclease RXT2_N PF08595.6 KOS17557.1 - 0.0069 16.1 11.8 0.016 14.9 3.3 2.4 2 0 0 2 2 2 2 RXT2-like, N-terminal TFIIA PF03153.8 KOS17557.1 - 0.017 15.0 9.7 0.023 14.6 6.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleoplasmin PF03066.10 KOS17557.1 - 0.027 13.9 17.7 0.17 11.4 8.9 2.3 2 0 0 2 2 2 0 Nucleoplasmin Adeno_terminal PF02459.10 KOS17557.1 - 0.23 9.5 1.4 0.39 8.8 0.9 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein PH PF00169.24 KOS17559.1 - 1.1e-10 41.6 0.0 2.4e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 KOS17559.1 - 0.0021 15.6 0.1 0.003 15.2 0.1 1.1 1 0 0 1 1 1 1 Prominin DUF2724 PF10893.3 KOS17559.1 - 0.048 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) FCH PF00611.18 KOS17559.1 - 0.051 13.7 0.2 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain RRF PF01765.14 KOS17559.1 - 0.18 11.2 2.2 0.3 10.5 1.5 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Gar1 PF04410.9 KOS17560.1 - 5e-40 136.4 2.9 1e-39 135.4 0.0 2.0 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region LCAT PF02450.10 KOS17561.1 - 2.6e-94 316.4 0.0 4.2e-94 315.7 0.0 1.3 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 KOS17561.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) DUF2013 PF09431.5 KOS17562.1 - 1.5e-48 164.0 2.5 1.5e-48 164.0 1.7 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2013) uDENN PF03456.13 KOS17562.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 uDENN domain DUF500 PF04366.7 KOS17563.1 - 2.7e-37 126.9 0.0 8.6e-37 125.3 0.0 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF500) VPS28 PF03997.7 KOS17564.1 - 3.5e-55 186.5 0.1 4.2e-55 186.3 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein Plectin PF00681.15 KOS17564.1 - 0.025 14.0 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Plectin repeat GvpG PF05120.7 KOS17564.1 - 0.19 11.5 3.9 0.36 10.6 0.2 2.2 2 0 0 2 2 2 0 Gas vesicle protein G KH_1 PF00013.24 KOS17565.1 - 0.036 13.7 0.0 0.085 12.5 0.0 1.6 1 0 0 1 1 1 0 KH domain ADH_zinc_N PF00107.21 KOS17566.1 - 2e-17 62.9 0.1 2.9e-17 62.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KOS17566.1 - 4.1e-07 30.9 0.0 8.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KOS17566.1 - 0.032 14.0 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Glyco_hydro_61 PF03443.9 KOS17567.1 - 1e-37 130.0 0.1 3.1e-37 128.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Cpn10 PF00166.16 KOS17568.1 - 7.3e-29 99.5 0.0 8.4e-29 99.3 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Phenyl_P_gamma PF09662.5 KOS17568.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 1 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) Pkinase PF00069.20 KOS17569.1 - 1.3e-58 198.2 0.0 2.8e-58 197.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17569.1 - 5.8e-21 74.7 0.0 1.3e-20 73.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KOS17569.1 - 0.002 17.9 0.4 0.0095 15.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ribosomal_L11_N PF03946.9 KOS17570.1 - 6.4e-26 89.5 0.1 1e-25 88.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KOS17570.1 - 1.5e-22 79.4 0.9 2.3e-22 78.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain AAA PF00004.24 KOS17571.1 - 3.8e-51 172.7 0.0 2.1e-39 134.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KOS17571.1 - 5.2e-07 29.8 0.1 0.062 13.2 0.3 4.3 2 2 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.7 KOS17571.1 - 2e-05 23.7 0.0 0.00068 18.7 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KOS17571.1 - 8e-05 22.3 3.5 0.023 14.4 0.0 4.5 4 1 0 4 4 4 1 Part of AAA domain AAA_22 PF13401.1 KOS17571.1 - 9.9e-05 22.4 0.2 0.47 10.5 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KOS17571.1 - 0.00015 21.5 0.0 0.13 11.9 0.0 3.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KOS17571.1 - 0.00015 21.2 3.4 1.7 7.9 0.0 4.0 3 2 2 5 5 5 2 AAA domain AAA_28 PF13521.1 KOS17571.1 - 0.0003 20.7 0.0 0.0064 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 KOS17571.1 - 0.00065 19.7 0.0 0.18 11.8 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_14 PF13173.1 KOS17571.1 - 0.0013 18.6 0.0 0.72 9.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KOS17571.1 - 0.0038 16.8 1.5 3.1 7.4 0.2 3.6 3 1 1 4 4 4 1 NACHT domain IstB_IS21 PF01695.12 KOS17571.1 - 0.0076 15.6 0.1 3.6 6.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 KOS17571.1 - 0.023 15.5 0.0 0.17 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KOS17571.1 - 0.023 14.8 0.0 3.5 7.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_2 PF07724.9 KOS17571.1 - 0.08 12.8 0.0 0.57 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) TSA PF03249.8 KOS17572.1 - 0.28 9.6 2.2 0.52 8.7 1.5 1.4 1 0 0 1 1 1 0 Type specific antigen Trypan_PARP PF05887.6 KOS17572.1 - 1.3 8.8 6.1 0.81 9.4 2.1 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Ras PF00071.17 KOS17573.1 - 2e-64 215.8 0.0 2.4e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS17573.1 - 2.7e-19 69.8 0.0 3.7e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS17573.1 - 2.9e-13 49.4 0.0 3.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KOS17573.1 - 1.8e-06 27.5 0.0 3.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KOS17573.1 - 5.4e-06 25.7 0.0 6.2e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KOS17573.1 - 0.0054 16.6 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KOS17573.1 - 0.037 13.2 0.0 0.044 13.0 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.24 KOS17573.1 - 0.074 13.2 0.0 5.2 7.2 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KOS17573.1 - 0.082 12.0 0.0 0.22 10.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 KOS17573.1 - 0.11 11.8 0.0 0.49 9.6 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 KOS17573.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KOS17573.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 KOS17573.1 - 0.14 10.8 0.4 14 4.2 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit U-box PF04564.10 KOS17574.1 - 3.4e-06 26.9 0.0 6.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 KOS17574.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RPAP1_N PF08621.5 KOS17574.1 - 0.12 11.9 0.5 0.66 9.6 0.0 2.3 3 0 0 3 3 3 0 RPAP1-like, N-terminal DUF165 PF02592.10 KOS17574.1 - 2.7 8.1 9.2 0.48 10.6 1.6 2.4 1 1 0 2 2 2 0 Uncharacterized ACR, YhhQ family COG1738 Malic_M PF03949.10 KOS17575.1 - 3.3e-66 223.4 0.0 4.5e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KOS17575.1 - 2e-57 193.7 0.0 2.9e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain MIF4G PF02854.14 KOS17576.1 - 2e-24 86.2 0.1 5e-24 84.8 0.1 1.7 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 KOS17576.1 - 4.7e-22 77.8 0.0 1.6e-21 76.0 0.0 2.0 2 0 0 2 2 2 1 MA3 domain HAD_2 PF13419.1 KOS17576.1 - 0.029 14.5 0.1 3.5 7.8 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase FAM176 PF14851.1 KOS17576.1 - 0.21 11.2 4.2 0.62 9.7 2.5 2.1 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.9 KOS17576.1 - 2 6.3 15.8 2.5 6.0 6.4 2.2 2 0 0 2 2 2 0 CDC45-like protein TRAP_alpha PF03896.11 KOS17576.1 - 3.3 6.6 8.1 6 5.7 5.6 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Corona_nucleoca PF00937.13 KOS17576.1 - 3.8 6.3 12.1 0.53 9.1 5.0 1.9 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein adh_short PF00106.20 KOS17577.1 - 1.4e-18 67.3 3.0 2.1e-18 66.8 1.9 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS17577.1 - 1.9e-09 37.4 3.8 8.3e-09 35.3 2.5 2.1 1 1 1 2 2 2 1 KR domain PTB PF08416.8 KOS17577.1 - 0.088 12.7 0.1 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotyrosine-binding domain Daxx PF03344.10 KOS17578.1 - 0.39 9.1 19.1 0.59 8.5 13.2 1.2 1 0 0 1 1 1 0 Daxx Family PHD PF00628.24 KOS17579.1 - 3e-06 26.8 7.6 1.5e-05 24.6 0.8 2.6 2 0 0 2 2 2 2 PHD-finger ING PF12998.2 KOS17579.1 - 0.00076 19.7 6.7 0.00076 19.7 0.0 2.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Bactofilin PF04519.8 KOS17580.1 - 1.2e-07 31.6 2.6 0.00033 20.5 0.1 2.4 1 1 1 2 2 2 2 Polymer-forming cytoskeletal DUF342 PF03961.8 KOS17580.1 - 0.00012 20.6 0.7 0.00022 19.7 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF342) MinC_C PF03775.11 KOS17580.1 - 0.00078 19.0 2.9 0.52 9.9 0.0 2.9 1 1 2 3 3 3 2 Septum formation inhibitor MinC, C-terminal domain DUF748 PF05359.6 KOS17580.1 - 0.01 15.8 0.0 0.4 10.6 0.0 2.4 1 1 2 3 3 3 0 Domain of Unknown Function (DUF748) Fil_haemagg PF05594.9 KOS17580.1 - 0.3 11.4 1.4 2.5 8.4 1.0 2.4 1 1 0 1 1 1 0 Haemagluttinin repeat Sugar_tr PF00083.19 KOS17581.1 - 2.5e-75 253.7 20.1 2.9e-75 253.5 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS17581.1 - 9.3e-30 103.5 29.1 2.5e-25 88.9 11.5 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KOS17581.1 - 2.8e-06 25.8 1.2 2.8e-06 25.8 0.9 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MSP1b PF03429.8 KOS17581.1 - 0.097 10.5 0.1 0.14 10.0 0.1 1.1 1 0 0 1 1 1 0 Major surface protein 1B ComX PF05952.7 KOS17581.1 - 0.13 11.7 0.0 0.37 10.3 0.0 1.7 1 0 0 1 1 1 0 Bacillus competence pheromone ComX GRAM PF02893.15 KOS17582.1 - 6.5e-17 60.8 0.0 1.1e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Apc15p PF05841.6 KOS17583.1 - 0.21 12.3 1.7 0.28 11.9 1.2 1.2 1 0 0 1 1 1 0 Apc15p protein Med15 PF09606.5 KOS17584.1 - 0.0017 16.6 102.1 0.0031 15.8 70.8 1.4 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal zf-C2H2_4 PF13894.1 KOS17585.1 - 0.0086 16.3 15.6 0.33 11.3 0.1 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-RING_3 PF14369.1 KOS17585.1 - 0.075 13.0 3.0 0.29 11.1 2.1 2.1 1 0 0 1 1 1 0 zinc-finger DHC_N1 PF08385.7 KOS17586.1 - 1.6e-179 598.0 7.8 1.6e-179 598.0 5.4 4.2 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KOS17586.1 - 2e-128 428.4 6.8 2e-128 428.4 4.7 5.1 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 KOS17586.1 - 8.4e-108 361.2 0.0 2.9e-107 359.5 0.0 1.8 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KOS17586.1 - 2.8e-77 259.3 0.0 9.1e-77 257.6 0.0 1.9 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KOS17586.1 - 2.7e-42 144.1 0.1 6.9e-42 142.8 0.0 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 KOS17586.1 - 4.3e-40 137.5 11.0 8.9e-40 136.4 7.7 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.2 KOS17586.1 - 3.4e-39 134.4 0.2 4.3e-38 130.8 0.1 2.4 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 KOS17586.1 - 1.7e-32 112.0 0.0 1.6e-12 47.3 0.0 6.3 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KOS17586.1 - 8.8e-22 77.4 0.0 4.7e-20 71.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 KOS17586.1 - 2.4e-14 53.6 0.1 0.022 14.8 0.0 6.2 6 0 0 6 6 5 3 AAA domain AAA PF00004.24 KOS17586.1 - 1.2e-13 51.4 0.0 0.0035 17.5 0.0 5.2 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KOS17586.1 - 5.8e-10 39.2 0.1 0.35 10.7 0.0 5.5 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 KOS17586.1 - 8.3e-10 39.5 0.0 0.03 15.1 0.0 6.1 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 KOS17586.1 - 4.2e-09 36.7 3.2 0.028 14.7 0.0 6.5 6 0 0 6 6 5 2 AAA domain AAA_16 PF13191.1 KOS17586.1 - 5.8e-09 36.2 15.7 0.075 13.0 0.0 8.9 8 1 1 9 9 9 2 AAA ATPase domain T2SE PF00437.15 KOS17586.1 - 2.1e-06 26.8 0.0 0.089 11.6 0.0 3.8 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_19 PF13245.1 KOS17586.1 - 6.8e-06 25.7 0.1 0.88 9.3 0.0 4.6 4 0 0 4 4 4 1 Part of AAA domain AAA_14 PF13173.1 KOS17586.1 - 2e-05 24.4 0.0 0.31 10.9 0.0 5.2 5 0 0 5 5 3 1 AAA domain AAA_29 PF13555.1 KOS17586.1 - 2.6e-05 23.6 0.0 2 7.9 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_tran PF00005.22 KOS17586.1 - 0.00012 22.4 0.5 4.2 7.6 0.0 5.1 4 0 0 4 4 3 1 ABC transporter Mg_chelatase PF01078.16 KOS17586.1 - 0.0002 20.5 1.0 0.5 9.4 0.0 3.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KOS17586.1 - 0.00055 19.4 0.3 0.36 10.2 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KOS17586.1 - 0.0036 17.4 0.1 14 5.9 0.0 4.8 4 0 0 4 4 4 0 RNA helicase AAA_25 PF13481.1 KOS17586.1 - 0.0047 16.3 0.1 0.5 9.7 0.0 3.8 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 KOS17586.1 - 0.018 14.7 0.1 10 5.8 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ACPS PF01648.15 KOS17588.1 - 0.0034 17.1 0.0 0.0049 16.6 0.0 1.2 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF1774 PF08611.5 KOS17589.1 - 5.1e-32 109.8 1.0 5.1e-32 109.8 0.7 2.7 3 1 0 3 3 3 1 Fungal protein of unknown function (DUF1774) CENP-Q PF13094.1 KOS17590.1 - 8e-07 29.2 0.1 8e-07 29.2 0.1 3.3 3 1 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Serglycin PF04360.7 KOS17590.1 - 0.031 14.0 1.1 0.05 13.3 0.0 1.9 2 0 0 2 2 2 0 Serglycin Sec34 PF04136.10 KOS17590.1 - 0.065 12.9 3.0 0.41 10.3 0.1 2.3 2 0 0 2 2 2 0 Sec34-like family DUF3829 PF12889.2 KOS17590.1 - 0.075 12.2 6.8 2 7.5 1.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3829) Cytadhesin_P30 PF07271.6 KOS17590.1 - 0.094 11.9 1.2 0.19 11.0 0.8 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF972 PF06156.8 KOS17590.1 - 0.11 12.8 11.7 1.5 9.2 2.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Ax_dynein_light PF10211.4 KOS17590.1 - 0.19 11.5 14.0 1.4 8.7 0.0 2.7 3 0 0 3 3 3 0 Axonemal dynein light chain Herpes_UL6 PF01763.11 KOS17590.1 - 0.22 9.6 5.5 0.14 10.3 1.9 1.9 1 1 0 2 2 2 0 Herpesvirus UL6 like Dor1 PF04124.7 KOS17590.1 - 0.31 9.4 9.0 0.17 10.3 0.9 3.0 3 0 0 3 3 3 0 Dor1-like family bZIP_1 PF00170.16 KOS17590.1 - 0.52 10.2 14.3 0.62 10.0 0.1 3.3 3 1 0 3 3 3 0 bZIP transcription factor TMF_DNA_bd PF12329.3 KOS17590.1 - 1 9.1 18.2 0.84 9.4 4.6 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.15 KOS17590.1 - 1.1 9.0 13.5 0.1 12.3 2.1 2.9 3 0 0 3 3 2 0 Prefoldin subunit Med9 PF07544.8 KOS17590.1 - 1.3 8.8 10.5 0.57 9.9 1.8 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF3166 PF11365.3 KOS17590.1 - 3.5 8.1 9.0 0.75 10.2 1.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3166) APG6 PF04111.7 KOS17590.1 - 3.7 6.5 13.5 1.7 7.6 4.8 2.6 2 1 0 2 2 2 0 Autophagy protein Apg6 HALZ PF02183.13 KOS17590.1 - 4.2 7.1 9.7 17 5.1 2.0 2.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper Prefoldin PF02996.12 KOS17590.1 - 6.5 6.4 10.1 15 5.2 0.1 3.2 3 0 0 3 3 3 0 Prefoldin subunit BLOC1_2 PF10046.4 KOS17590.1 - 8.5 6.5 9.5 4.7 7.4 0.9 2.9 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cupin_8 PF13621.1 KOS17591.1 - 8.9e-30 104.0 0.0 1.3e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KOS17591.1 - 4.8e-05 22.7 0.0 0.0016 17.7 0.0 2.2 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 KOS17591.1 - 7.1e-05 23.0 0.0 0.00034 20.8 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KOS17591.1 - 0.04 13.4 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Cupin domain SF3b10 PF07189.6 KOS17592.1 - 5.3e-34 115.8 0.0 6.1e-34 115.6 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Rpn3_C PF08375.6 KOS17593.1 - 2.4e-25 88.7 1.9 7.5e-25 87.1 1.3 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KOS17593.1 - 1.9e-20 73.1 1.0 6.8e-20 71.3 0.0 2.4 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.12 KOS17593.1 - 0.0061 16.3 0.1 0.021 14.6 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TFIID_20kDa PF03847.8 KOS17594.1 - 5.7e-17 61.7 0.0 8.9e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DASH_Spc34 PF08657.5 KOS17595.1 - 2.1e-49 168.5 2.6 1.8e-48 165.4 1.8 1.9 1 1 0 1 1 1 1 DASH complex subunit Spc34 Ribosomal_60s PF00428.14 KOS17595.1 - 0.0013 19.0 6.7 0.0013 19.0 4.6 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein CobT PF06213.7 KOS17595.1 - 0.039 13.0 12.1 0.056 12.5 8.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 KOS17595.1 - 0.1 11.8 7.7 0.16 11.1 5.3 1.2 1 0 0 1 1 1 0 NOA36 protein VID27 PF08553.5 KOS17595.1 - 0.14 10.4 11.4 0.19 9.8 7.9 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nop14 PF04147.7 KOS17595.1 - 0.17 9.7 13.4 0.25 9.2 9.3 1.3 1 0 0 1 1 1 0 Nop14-like family Glypican PF01153.14 KOS17595.1 - 0.5 8.9 4.2 0.83 8.1 2.9 1.3 1 0 0 1 1 1 0 Glypican Pap_E4 PF02711.9 KOS17595.1 - 1.9 9.3 7.3 6.5 7.6 5.1 1.9 1 0 0 1 1 1 0 E4 protein Paf1 PF03985.8 KOS17595.1 - 2.7 6.6 13.3 5.1 5.7 9.2 1.4 1 0 0 1 1 1 0 Paf1 zf-RING_2 PF13639.1 KOS17596.1 - 7.5e-08 32.0 10.7 1.5e-07 31.1 7.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KOS17596.1 - 1.7e-07 31.1 8.5 3.1e-07 30.2 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS17596.1 - 4.3e-07 29.4 8.7 7.3e-07 28.7 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS17596.1 - 3.1e-06 26.7 7.4 4.9e-06 26.1 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KOS17596.1 - 0.00016 21.7 8.8 0.0004 20.4 6.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-piccolo PF05715.8 KOS17596.1 - 0.053 13.5 3.0 3 7.9 0.7 2.6 2 0 0 2 2 2 0 Piccolo Zn-finger zf-RING_5 PF14634.1 KOS17596.1 - 0.13 11.9 10.5 0.23 11.1 7.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DNA_pol_A_exo1 PF01612.15 KOS17597.1 - 1.9e-39 134.9 0.3 3e-39 134.3 0.2 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KOS17597.1 - 2.3e-23 82.3 0.4 6.7e-23 80.8 0.3 1.9 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 KOS17597.1 - 2e-12 46.6 0.0 5.5e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 HRDC domain Casc1 PF12366.3 KOS17597.1 - 0.0074 15.8 0.0 0.0074 15.8 0.0 2.4 2 0 0 2 2 2 1 Cancer susceptibility candidate 1 ATP-synt_C PF00137.16 KOS17598.1 - 4.2e-16 58.5 10.2 6.9e-16 57.9 7.1 1.4 1 0 0 1 1 1 1 ATP synthase subunit C MOZ_SAS PF01853.13 KOS17599.1 - 3.6e-50 169.8 0.0 1.4e-49 167.9 0.0 1.8 2 0 0 2 2 2 1 MOZ/SAS family LRR_6 PF13516.1 KOS17600.1 - 2.8e-11 42.2 0.0 0.17 12.0 0.0 7.2 7 0 0 7 7 7 3 Leucine Rich repeat 5_nucleotid_C PF02872.13 KOS17601.1 - 4.9e-29 101.3 0.0 8.2e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KOS17601.1 - 9.9e-12 44.6 1.7 1.4e-11 44.1 1.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YmdB PF13277.1 KOS17601.1 - 0.0013 17.8 0.0 0.0025 16.9 0.0 1.4 1 0 0 1 1 1 1 YmdB-like protein Glyco_transf_20 PF00982.16 KOS17602.1 - 1.9e-196 653.1 0.0 2.1e-196 652.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 KOS17602.1 - 0.07 12.6 0.1 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain Mis14 PF08641.7 KOS17603.1 - 0.0022 18.0 0.3 0.009 16.0 0.0 2.0 3 0 0 3 3 3 1 Kinetochore protein Mis14 like Aminotran_3 PF00202.16 KOS17604.1 - 2e-45 155.1 0.1 2.2e-45 154.9 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KOS17604.1 - 0.018 14.2 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase AIRC PF00731.15 KOS17605.1 - 2.7e-61 205.2 1.1 6e-61 204.1 0.7 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 KOS17605.1 - 5.6e-49 165.7 0.0 1.2e-48 164.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KOS17605.1 - 2.7e-10 40.2 0.1 1.3e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KOS17605.1 - 2.4e-06 27.0 0.0 4.9e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 KOS17605.1 - 0.033 13.3 0.0 0.072 12.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 KOS17605.1 - 0.11 10.9 0.1 0.19 10.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Yae1_N PF09811.4 KOS17606.1 - 1.7e-13 49.8 0.6 3.1e-13 49.0 0.4 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Romo1 PF10247.4 KOS17606.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF605 PF04652.11 KOS17607.1 - 0.17 11.2 11.0 0.2 11.0 7.6 1.2 1 0 0 1 1 1 0 Vta1 like FIST PF08495.5 KOS17607.1 - 0.19 10.8 2.4 0.28 10.3 0.4 2.2 2 1 0 2 2 2 0 FIST N domain SOG2 PF10428.4 KOS17607.1 - 0.28 9.7 6.3 0.34 9.5 4.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SR-25 PF10500.4 KOS17607.1 - 2.4 7.5 12.3 4.2 6.7 8.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein p450 PF00067.17 KOS17608.1 - 1.2e-46 159.1 0.0 4.8e-36 124.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 GTP_EFTU PF00009.22 KOS17610.1 - 8.6e-45 152.4 0.0 1.4e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KOS17610.1 - 4.7e-37 126.1 0.0 1.2e-36 124.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KOS17610.1 - 4.3e-17 61.9 0.8 1.2e-16 60.5 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KOS17610.1 - 0.00014 21.4 0.2 0.00036 20.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MFS_1 PF07690.11 KOS17611.1 - 8.9e-44 149.6 22.4 8.1e-40 136.6 6.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS17611.1 - 1.2e-13 50.4 1.7 2.1e-13 49.6 1.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF791 PF05631.9 KOS17611.1 - 0.0004 19.2 0.3 0.0004 19.2 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF791) TRI12 PF06609.8 KOS17611.1 - 0.0082 14.3 1.8 0.014 13.6 1.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KOS17611.1 - 0.041 13.6 2.4 0.23 11.2 0.0 2.7 2 0 0 2 2 2 0 MFS_1 like family FPN1 PF06963.7 KOS17611.1 - 0.081 11.2 5.3 0.98 7.7 0.2 2.9 1 1 2 3 3 3 0 Ferroportin1 (FPN1) CagX PF03524.10 KOS17611.1 - 0.8 8.9 4.3 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 Conjugal transfer protein TSA PF03249.8 KOS17611.1 - 5.7 5.3 6.7 8.4 4.8 4.6 1.1 1 0 0 1 1 1 0 Type specific antigen MAGE PF01454.14 KOS17612.1 - 5.8e-38 130.2 0.0 7.1e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 MAGE family DUF702 PF05142.7 KOS17612.1 - 0.032 14.4 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) SLS PF14611.1 KOS17613.1 - 7.3e-33 113.7 0.0 1.1e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Longin PF13774.1 KOS17614.1 - 3.3e-16 58.6 0.0 5.7e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KOS17614.1 - 3.3e-14 52.2 0.5 5.2e-14 51.6 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Imm43 PF15602.1 KOS17614.1 - 0.081 12.8 0.7 0.93 9.4 0.0 2.3 3 0 0 3 3 3 0 Immunity protein 43 Sec16 PF12932.2 KOS17615.1 - 8.2 6.4 6.8 2.8e+02 1.5 2.9 3.6 2 1 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region Ras PF00071.17 KOS17616.1 - 1.1e-41 141.9 0.0 5.2e-41 139.7 0.0 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KOS17616.1 - 1.6e-17 64.0 0.0 2.2e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS17616.1 - 1.5e-10 40.6 0.0 2.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KOS17616.1 - 0.0054 16.6 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KOS17616.1 - 0.019 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KOS17616.1 - 0.03 14.4 0.0 0.077 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 KOS17616.1 - 0.031 13.4 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_5 PF07728.9 KOS17616.1 - 0.039 13.6 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KOS17616.1 - 0.04 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KOS17616.1 - 0.054 13.4 0.2 0.29 11.0 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 KOS17616.1 - 0.096 12.6 0.3 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KOS17616.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain Sec63 PF02889.11 KOS17617.1 - 5e-144 479.3 0.0 2.5e-96 322.6 0.6 2.8 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KOS17617.1 - 1e-53 181.2 0.5 2.6e-28 98.6 0.2 3.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS17617.1 - 2.7e-17 62.3 0.0 3.7e-07 29.8 0.0 3.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 KOS17617.1 - 3.8e-15 56.1 0.0 2e-06 27.7 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KOS17617.1 - 2.5e-07 30.9 0.2 0.043 13.9 0.0 3.6 2 2 0 2 2 2 2 AAA domain SNF2_N PF00176.18 KOS17617.1 - 2.3e-05 23.3 0.2 0.11 11.2 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_19 PF13245.1 KOS17617.1 - 3.1e-05 23.6 0.4 0.18 11.5 0.0 3.2 3 0 0 3 3 3 2 Part of AAA domain AAA PF00004.24 KOS17617.1 - 0.0026 17.9 0.5 1.5 9.0 0.0 3.7 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KOS17617.1 - 0.011 15.1 0.1 19 4.6 0.0 4.3 5 0 0 5 5 5 0 IstB-like ATP binding protein AAA_10 PF12846.2 KOS17617.1 - 0.018 14.4 0.0 7.3 5.9 0.0 3.5 3 1 1 4 4 4 0 AAA-like domain YL1_C PF08265.6 KOS17618.1 - 4.5e-16 58.0 0.0 7.4e-16 57.4 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF566 PF04484.7 KOS17618.1 - 0.34 10.3 5.9 0.42 10.0 4.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DASH_Dad4 PF08650.5 KOS17619.1 - 6.3e-29 99.7 6.9 6.8e-29 99.5 4.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.12 KOS17619.1 - 0.015 15.2 0.7 0.017 15.0 0.5 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor DASH_Dad1 PF08649.5 KOS17619.1 - 0.025 14.2 3.5 0.031 13.9 2.4 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad1 Pecanex_C PF05041.10 KOS17619.1 - 0.03 13.3 0.2 0.034 13.1 0.2 1.0 1 0 0 1 1 1 0 Pecanex protein (C-terminus) Profilin PF00235.14 KOS17620.1 - 1.3e-36 125.3 0.4 1.5e-36 125.1 0.3 1.0 1 0 0 1 1 1 1 Profilin Got1 PF04178.7 KOS17621.1 - 1.9e-18 66.7 11.7 2.1e-18 66.5 8.1 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 KOS17621.1 - 0.0016 18.1 3.6 0.0016 18.1 2.5 2.5 2 0 0 2 2 2 2 YrhK-like protein DUF4620 PF15399.1 KOS17622.1 - 1.1 9.3 4.2 20 5.3 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4620) SUR7 PF06687.7 KOS17623.1 - 7.4e-24 84.4 1.0 8.4e-24 84.3 0.7 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 KOS17623.1 - 0.089 12.6 9.1 0.15 11.9 4.1 2.1 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 PIG-P PF08510.7 KOS17623.1 - 3.4 7.2 5.2 0.91 9.1 0.1 2.3 2 1 0 2 2 2 0 PIG-P Biotin_lipoyl PF00364.17 KOS17624.1 - 7.8e-20 70.2 0.6 1.7e-19 69.1 0.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KOS17624.1 - 3.2e-07 29.8 0.2 1e-06 28.2 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KOS17624.1 - 5.1e-05 22.8 0.1 0.00046 19.7 0.0 2.6 2 1 0 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 KOS17624.1 - 0.059 12.5 0.1 0.75 8.8 0.1 2.0 1 1 0 1 1 1 0 HlyD family secretion protein HlyD_3 PF13437.1 KOS17624.1 - 0.1 12.9 0.0 0.39 11.0 0.0 1.9 1 1 1 2 2 2 0 HlyD family secretion protein QRPTase_N PF02749.11 KOS17624.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain DUF2360 PF10152.4 KOS17624.1 - 1.6 9.0 5.6 2.4 8.4 1.9 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) RAP1 PF07218.6 KOS17624.1 - 2.1 6.3 4.6 2.8 5.9 3.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Evr1_Alr PF04777.8 KOS17625.1 - 1e-29 102.2 0.1 2e-28 98.1 0.0 2.0 2 0 0 2 2 2 1 Erv1 / Alr family TPP_enzyme_N PF02776.13 KOS17626.1 - 4.6e-30 104.3 0.0 8e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KOS17626.1 - 3.1e-21 75.5 0.0 6.7e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KOS17626.1 - 4.2e-14 52.4 0.0 1.2e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SGT1 PF07093.6 KOS17627.1 - 1.6e-133 446.2 22.3 2.5e-132 442.2 15.4 1.9 1 1 0 1 1 1 1 SGT1 protein SMC_N PF02463.14 KOS17628.1 - 4e-20 71.9 11.5 5.5e-19 68.2 7.9 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KOS17628.1 - 4.2e-15 56.6 12.0 4.2e-15 56.6 8.3 5.7 3 2 1 4 4 4 1 AAA domain AAA_21 PF13304.1 KOS17628.1 - 7.8e-07 29.3 1.2 0.00029 20.9 0.1 3.0 3 0 0 3 3 3 2 AAA domain SMC_hinge PF06470.8 KOS17628.1 - 0.00037 20.4 0.3 0.0062 16.4 0.0 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain SbcCD_C PF13558.1 KOS17628.1 - 0.00095 19.0 0.0 0.0027 17.5 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 KOS17628.1 - 0.0016 17.5 0.1 0.0016 17.5 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 KOS17628.1 - 0.0018 17.7 0.0 0.0043 16.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain THUMP PF02926.12 KOS17630.1 - 3.7e-12 46.3 0.7 5e-11 42.6 0.5 2.0 1 1 0 1 1 1 1 THUMP domain SRP14 PF02290.10 KOS17631.1 - 6.1e-20 70.9 0.0 1.1e-19 70.0 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle 14kD protein MIF4G PF02854.14 KOS17632.1 - 2.1e-17 63.2 0.1 3.8e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 KOS17632.1 - 5.6e-09 35.6 0.0 1.5e-07 31.1 0.0 3.0 2 2 1 3 3 3 1 MA3 domain COQ9 PF08511.6 KOS17633.1 - 2.4e-25 87.8 0.0 4e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 COQ9 RRM_1 PF00076.17 KOS17634.1 - 7.5e-36 121.6 0.0 1.6e-17 62.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS17634.1 - 4.2e-30 103.5 0.0 4.9e-15 55.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS17634.1 - 4.3e-17 61.6 0.0 1.2e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.5 KOS17634.1 - 0.0016 17.8 0.0 0.023 14.0 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain RRM_3 PF08777.6 KOS17634.1 - 0.0098 15.7 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.3 KOS17634.1 - 0.012 15.3 0.0 2.3 8.0 0.0 2.9 2 2 0 2 2 2 0 Limkain b1 HSP70 PF00012.15 KOS17635.1 - 1.5e-75 254.3 2.6 1.9e-75 253.9 1.8 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KOS17635.1 - 1.3e-06 27.2 0.5 2.8e-06 26.1 0.4 1.6 1 1 0 1 1 1 1 MreB/Mbl protein Nucleoplasmin PF03066.10 KOS17635.1 - 0.00087 18.8 2.8 0.00087 18.8 2.0 2.0 2 0 0 2 2 2 1 Nucleoplasmin CENP-B_dimeris PF09026.5 KOS17635.1 - 0.0014 18.7 6.1 0.0052 17.0 3.6 2.2 2 0 0 2 2 2 1 Centromere protein B dimerisation domain Hydantoinase_A PF01968.13 KOS17635.1 - 0.0022 17.1 0.2 0.011 14.9 0.1 2.1 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase Cwf_Cwc_15 PF04889.7 KOS17635.1 - 0.023 14.4 2.4 0.045 13.4 1.7 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.6 KOS17635.1 - 0.29 10.9 4.5 0.68 9.7 3.1 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Tom22 PF04281.8 KOS17635.1 - 0.45 10.0 3.5 1.3 8.5 2.4 1.8 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Sigma70_ner PF04546.8 KOS17635.1 - 0.55 9.8 12.8 0.46 10.0 5.1 2.5 3 0 0 3 3 3 0 Sigma-70, non-essential region FAM176 PF14851.1 KOS17635.1 - 1.3 8.6 3.9 1.9 8.1 1.1 2.2 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.1 KOS17635.1 - 7.5 6.9 18.1 1.6 9.0 10.0 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 KOS17635.1 - 8.5 4.1 10.0 17 3.1 6.9 1.4 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_4 PF13894.1 KOS17637.1 - 7.3e-06 25.9 23.3 0.0005 20.1 0.6 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KOS17637.1 - 1.3e-05 25.2 32.9 0.001 19.2 1.0 4.8 5 0 0 5 5 5 3 Zinc finger, C2H2 type Adeno_E3_CR2 PF02439.10 KOS17637.1 - 0.025 14.1 0.2 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.15 KOS17637.1 - 0.047 13.3 0.3 0.58 9.8 0.0 2.3 2 0 0 2 2 2 0 Syndecan domain DUF3487 PF11990.3 KOS17637.1 - 0.087 12.2 0.1 0.2 11.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Sina PF03145.11 KOS17637.1 - 9.3 5.8 12.6 8.8 5.9 7.3 1.8 1 1 1 2 2 2 0 Seven in absentia protein family GAF_2 PF13185.1 KOS17638.1 - 0.13 12.7 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 GAF domain Pox_A12 PF04651.8 KOS17638.1 - 0.21 11.7 15.0 0.37 10.8 10.4 1.5 1 0 0 1 1 1 0 Poxvirus A12 protein Hid1 PF12722.2 KOS17638.1 - 0.68 7.5 7.6 0.8 7.2 5.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dicty_REP PF05086.7 KOS17638.1 - 2.1 5.9 13.9 2.6 5.6 9.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein EAF PF09816.4 KOS17639.1 - 3.3e-19 68.8 1.1 7.4e-19 67.7 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase II transcription elongation factor Med3 PF11593.3 KOS17639.1 - 0.11 11.7 12.4 0.16 11.1 8.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SSP160 PF06933.6 KOS17639.1 - 1.8 6.4 16.8 2.6 5.9 11.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AJAP1_PANP_C PF15298.1 KOS17639.1 - 1.9 8.3 14.1 4 7.2 9.8 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Mucin PF01456.12 KOS17639.1 - 3.4 7.4 34.8 0.27 11.0 20.1 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Nucleo_P87 PF07267.6 KOS17639.1 - 8.2 4.9 22.5 0.57 8.8 12.1 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 POP1 PF06978.6 KOS17640.1 - 1.1e-57 194.7 11.5 1.7e-57 194.1 8.0 1.3 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KOS17640.1 - 1.6e-26 91.9 0.0 3.7e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain NT-C2 PF10358.4 KOS17641.1 - 3.5e-23 81.6 0.0 6.2e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Ribosomal_S28e PF01200.13 KOS17642.1 - 7e-32 108.9 2.9 7.4e-32 108.9 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e IBR PF01485.16 KOS17643.1 - 6.1e-09 35.6 31.4 0.00011 21.9 5.8 3.7 3 0 0 3 3 3 3 IBR domain zf-RING_2 PF13639.1 KOS17643.1 - 0.015 15.0 7.9 0.015 15.0 5.5 3.4 3 0 0 3 3 3 0 Ring finger domain Pterin_4a PF01329.14 KOS17644.1 - 1e-26 92.5 0.0 1.7e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase HK PF02110.10 KOS17645.1 - 1.5e-75 253.5 2.8 2.6e-75 252.7 1.9 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KOS17645.1 - 2.4e-57 192.9 0.8 4.9e-57 191.9 0.6 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 KOS17645.1 - 2.5e-06 26.9 2.5 3.8e-06 26.3 0.2 2.1 1 1 0 2 2 2 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KOS17645.1 - 2.5e-05 23.6 0.1 4.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Ribosomal_60s PF00428.14 KOS17645.1 - 0.14 12.6 0.3 0.59 10.5 0.2 2.2 1 1 0 1 1 1 0 60s Acidic ribosomal protein Zn_clus PF00172.13 KOS17646.1 - 0.049 13.5 6.6 0.085 12.7 4.5 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain STE3 PF02076.10 KOS17647.1 - 1.5e-39 135.7 9.0 1.9e-39 135.4 6.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF3816 PF12822.2 KOS17647.1 - 0.49 10.2 8.7 0.11 12.3 2.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3816) DUF4203 PF13886.1 KOS17648.1 - 9.1e-27 93.8 20.3 1.2e-26 93.5 14.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4570 PF15134.1 KOS17648.1 - 0.089 12.6 5.6 0.29 11.0 3.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF2029 PF09594.5 KOS17648.1 - 0.56 9.6 15.8 0.92 8.9 11.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) Bax1-I PF01027.15 KOS17648.1 - 2.4 7.7 19.6 4.1 6.9 13.6 1.3 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 GSH_synth_ATP PF03917.12 KOS17649.1 - 2e-110 368.8 0.0 2.4e-110 368.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KOS17649.1 - 6.1e-29 100.1 0.0 1.3e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SSB PF00436.20 KOS17650.1 - 6.8e-18 64.4 0.0 7.9e-18 64.2 0.0 1.0 1 0 0 1 1 1 1 Single-strand binding protein family BP28CT PF08146.7 KOS17651.1 - 2.4e-38 131.2 0.0 3.7e-37 127.4 0.0 3.0 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KOS17651.1 - 1.1e-24 86.6 0.8 1.1e-24 86.6 0.5 6.4 7 2 0 7 7 7 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 KOS17651.1 - 1.9e-07 30.5 6.8 0.04 13.9 0.1 5.7 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 KOS17651.1 - 4.7e-06 26.8 22.4 0.19 12.0 0.4 7.1 7 0 0 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 KOS17651.1 - 0.27 11.7 14.2 0.14 12.6 1.6 5.9 5 1 2 7 7 7 0 HEAT-like repeat Ribosomal_S26e PF01283.14 KOS17652.1 - 8.3e-46 154.9 6.2 8.3e-46 154.9 4.3 1.6 2 0 0 2 2 2 1 Ribosomal protein S26e P12 PF12669.2 KOS17652.1 - 0.013 15.6 4.6 0.051 13.7 3.2 2.0 1 1 0 1 1 1 0 Virus attachment protein p12 family DUF1918 PF08940.6 KOS17652.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) SMC_N PF02463.14 KOS17653.1 - 5.9e-77 257.8 8.6 1.1e-38 132.7 1.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KOS17653.1 - 1.1e-26 93.2 0.0 4.5e-26 91.1 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KOS17653.1 - 7.7e-13 49.0 1.9 4.9e-05 23.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KOS17653.1 - 0.00017 21.0 0.0 0.00036 19.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.2 KOS17653.1 - 0.00019 21.2 10.6 0.00019 21.2 7.3 7.8 4 2 6 10 10 10 2 Tropomyosin like IncA PF04156.9 KOS17653.1 - 0.00096 18.7 7.7 0.00096 18.7 5.3 7.6 3 2 5 8 8 8 3 IncA protein Lebercilin PF15619.1 KOS17653.1 - 0.0042 16.5 9.2 0.0042 16.5 6.3 6.2 3 2 1 5 5 5 1 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.1 KOS17653.1 - 0.056 11.9 96.9 0.0051 15.3 20.8 5.3 3 2 2 5 5 5 0 AAA domain TPR_MLP1_2 PF07926.7 KOS17653.1 - 0.088 12.5 119.6 0.061 13.0 14.3 8.3 2 2 4 7 7 7 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 KOS17653.1 - 6.2 5.3 108.5 0.076 11.6 11.0 6.9 3 2 3 6 6 6 0 Spc7 kinetochore protein NKAIN PF05640.9 KOS17654.1 - 0.042 12.7 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein IPK PF03770.11 KOS17655.1 - 8.9e-55 185.3 0.0 1.4e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase XPA_C PF05181.7 KOS17656.1 - 1.4e-28 98.2 3.0 2.6e-28 97.3 2.1 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 KOS17656.1 - 0.013 15.1 3.7 0.013 15.1 2.6 2.2 2 0 0 2 2 2 0 XPA protein N-terminal FRG1 PF06229.7 KOS17656.1 - 0.024 14.0 0.7 0.055 12.9 0.5 1.6 1 0 0 1 1 1 0 FRG1-like family zf-C3HC4_3 PF13920.1 KOS17656.1 - 0.23 11.1 7.1 0.094 12.4 2.8 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PGBA_C PF15437.1 KOS17656.1 - 1.2 9.3 12.4 0.076 13.1 0.7 2.5 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal ArfGap PF01412.13 KOS17656.1 - 1.9 8.2 7.9 0.12 12.2 0.9 2.2 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf YhfH PF14149.1 KOS17656.1 - 7.8 6.3 12.1 0.94 9.3 0.2 2.7 2 1 0 2 2 2 0 YhfH-like protein Pkinase PF00069.20 KOS17657.1 - 1e-50 172.3 0.0 3.8e-36 124.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17657.1 - 7.2e-22 77.6 0.0 2.4e-20 72.6 0.0 3.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS17657.1 - 3.8e-05 22.8 0.0 9.1e-05 21.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KOS17657.1 - 0.0026 17.5 3.0 0.0096 15.6 0.6 3.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family SMC_hinge PF06470.8 KOS17657.1 - 0.14 12.1 0.1 0.34 10.8 0.1 1.6 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain Glycos_transf_1 PF00534.15 KOS17658.1 - 3.3e-26 91.7 0.0 4.7e-15 55.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KOS17658.1 - 3.7e-10 40.1 6.4 3.7e-10 40.1 4.4 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 KOS17658.1 - 9.2e-09 35.2 0.0 0.005 16.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KOS17658.1 - 2.7e-08 34.0 0.6 0.0081 16.3 0.0 2.8 2 1 1 3 3 3 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KOS17658.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 ECH PF00378.15 KOS17659.1 - 1.6e-19 69.9 0.0 2e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KOS17659.1 - 0.021 14.5 0.2 7.1 6.4 0.1 2.3 2 0 0 2 2 2 0 Peptidase family S49 RabGAP-TBC PF00566.13 KOS17660.1 - 6.8e-44 149.8 0.0 1.1e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LRR_4 PF12799.2 KOS17661.1 - 2e-35 119.8 23.8 1e-08 34.6 1.9 8.7 5 3 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS17661.1 - 4.5e-29 99.9 26.4 9.5e-08 31.6 0.4 7.3 5 1 2 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 KOS17661.1 - 2.8e-13 47.9 29.6 3.4 8.0 0.1 13.8 11 3 3 14 14 14 3 Leucine Rich Repeat LRR_7 PF13504.1 KOS17661.1 - 5.2e-11 40.8 35.2 7.2 7.2 0.0 14.5 13 1 1 14 14 14 2 Leucine rich repeat LRR_6 PF13516.1 KOS17661.1 - 8e-08 31.5 17.8 0.96 9.7 0.0 10.0 9 2 2 11 11 10 2 Leucine Rich repeat LRR_9 PF14580.1 KOS17661.1 - 0.00067 19.2 9.3 0.98 8.9 1.0 4.6 3 1 2 5 5 5 2 Leucine-rich repeat Toxin_54 PF15533.1 KOS17661.1 - 0.025 14.8 0.2 0.058 13.6 0.1 1.6 1 0 0 1 1 1 0 Putative toxin 54 DUF4611 PF15387.1 KOS17661.1 - 0.082 13.0 6.6 0.26 11.4 3.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF1551 PF07585.6 KOS17661.1 - 0.093 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1551) Macoilin PF09726.4 KOS17661.1 - 0.3 9.3 2.4 0.42 8.8 1.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Nop14 PF04147.7 KOS17661.1 - 0.66 7.8 9.0 0.93 7.3 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 KOS17661.1 - 0.84 9.2 9.0 1.5 8.3 6.2 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Antibiotic_NAT PF02522.9 KOS17663.1 - 0.11 11.7 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase CorA PF01544.13 KOS17665.1 - 1.9e-13 50.1 0.0 3e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Glycoprotein_B PF00606.13 KOS17667.1 - 0.14 10.2 4.0 0.14 10.1 2.8 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Rpr2 PF04032.11 KOS17670.1 - 2.3e-22 78.6 0.2 3.6e-22 78.0 0.2 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-CGNR PF11706.3 KOS17670.1 - 0.11 12.0 1.9 0.27 10.7 1.3 1.7 1 0 0 1 1 1 0 CGNR zinc finger Cyclin PF08613.6 KOS17671.1 - 9.7e-15 55.2 0.0 2.1e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KOS17671.1 - 0.0013 18.3 0.1 0.0034 16.9 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain DEAD PF00270.24 KOS17672.1 - 1.8e-33 115.4 0.0 3.3e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS17672.1 - 1.9e-24 85.2 0.0 2.8e-23 81.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS17672.1 - 7.6e-06 25.8 0.1 2.8e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC4 PF02732.10 KOS17674.1 - 2e-23 82.7 0.0 3.9e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain ASF1_hist_chap PF04729.8 KOS17675.1 - 5.5e-66 220.9 0.0 7.7e-66 220.4 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Zip PF02535.17 KOS17675.1 - 1.1 8.2 4.6 1.4 7.8 3.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RasGAP PF00616.14 KOS17676.1 - 6.9e-54 182.5 0.2 1e-52 178.7 0.0 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KOS17676.1 - 8.7e-30 103.2 5.1 8.7e-30 103.2 3.6 2.0 2 0 0 2 2 2 1 RasGAP C-terminus MeMO_Hyd_G PF02964.11 KOS17676.1 - 0.037 13.9 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain Suf PF05843.9 KOS17678.1 - 1.5e-71 241.4 0.0 8.6e-69 232.3 0.0 3.4 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KOS17678.1 - 0.0082 16.6 0.0 0.85 10.4 0.0 3.9 2 1 1 3 3 3 1 Tetratricopeptide repeat Lgl_C PF08596.5 KOS17679.1 - 2.3e-114 381.9 0.0 3.6e-114 381.2 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KOS17679.1 - 0.00048 19.9 6.2 0.01 15.7 0.1 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat PAZ PF02170.17 KOS17680.1 - 4.6e-17 61.5 0.0 9.1e-17 60.6 0.0 1.5 1 1 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KOS17680.1 - 2.1e-11 43.0 0.0 5.3e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Clp1 PF06807.9 KOS17681.1 - 8.9e-09 35.3 0.0 7.7e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KOS17681.1 - 8.1e-05 22.3 0.0 0.00022 20.9 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KOS17681.1 - 0.00093 20.0 0.2 0.0022 18.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS17681.1 - 0.017 14.9 0.0 0.062 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KOS17681.1 - 0.045 13.7 0.4 0.11 12.4 0.3 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KOS17681.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Redoxin PF08534.5 KOS17683.1 - 1.2e-24 86.5 0.0 1.4e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KOS17683.1 - 0.0015 18.2 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family IBR PF01485.16 KOS17684.1 - 3.2e-22 78.1 43.8 2.8e-12 46.3 3.3 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 KOS17684.1 - 6.9e-06 25.9 7.6 6.9e-06 25.9 5.3 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS17684.1 - 5.1e-05 22.8 5.0 5.1e-05 22.8 3.5 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS17684.1 - 0.00057 19.6 7.2 0.00057 19.6 5.0 3.7 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 KOS17684.1 - 0.015 15.0 8.2 0.015 15.0 5.7 4.0 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_4 PF14570.1 KOS17684.1 - 0.051 13.1 37.9 0.16 11.6 7.0 3.9 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KOS17684.1 - 6 6.8 31.1 2.7 7.9 1.1 4.8 3 2 0 3 3 3 0 zinc finger of C3HC4-type, RING ECM11 PF15463.1 KOS17685.1 - 7.9e-41 139.6 0.3 1e-40 139.2 0.2 1.2 1 0 0 1 1 1 1 Extracellular mutant protein 11 Adaptin_binding PF10199.4 KOS17685.1 - 0.069 13.4 0.4 0.089 13.0 0.3 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 AvrRpt-cleavage PF05627.6 KOS17685.1 - 0.098 11.7 1.0 2.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Cleavage site for pathogenic type III effector avirulence factor Avr ADH_zinc_N PF00107.21 KOS17686.1 - 6.4e-24 83.9 1.3 2.6e-18 65.7 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KOS17686.1 - 3.8e-12 47.2 0.1 1.3e-11 45.4 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KOS17686.1 - 3.1e-06 26.9 0.0 2.3e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NOA36 PF06524.7 KOS17686.1 - 0.87 8.7 11.0 1.6 7.9 7.6 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 KOS17686.1 - 1.7 7.3 14.9 2.4 6.7 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 KOS17686.1 - 7.8 4.2 12.9 12 3.7 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family Methyltransf_23 PF13489.1 KOS17688.1 - 0.016 14.9 0.0 0.057 13.1 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain HLH PF00010.21 KOS17689.1 - 7.9e-07 28.6 0.0 2.1e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain tRNA-synt_2b PF00587.20 KOS17690.1 - 1.8e-46 157.8 0.0 2.5e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KOS17690.1 - 2.4e-07 30.5 0.0 5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Bromodomain PF00439.20 KOS17691.1 - 4.8e-29 100.1 0.3 2.5e-13 49.7 0.0 2.5 2 0 0 2 2 2 2 Bromodomain SGT1 PF07093.6 KOS17691.1 - 0.0065 14.9 7.0 0.0093 14.3 4.9 1.2 1 0 0 1 1 1 1 SGT1 protein Ycf1 PF05758.7 KOS17691.1 - 0.41 8.2 6.8 0.51 7.9 4.7 1.2 1 0 0 1 1 1 0 Ycf1 CENP-T PF15511.1 KOS17691.1 - 1.3 8.2 29.3 0.076 12.2 16.5 1.7 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T DDHD PF02862.12 KOS17691.1 - 3.2 7.5 6.3 7.6 6.2 4.4 1.6 1 0 0 1 1 1 0 DDHD domain Maf PF02545.9 KOS17692.1 - 2.2e-43 147.6 0.0 2.8e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein rRNA_proc-arch PF13234.1 KOS17693.1 - 3e-91 305.3 0.0 9.4e-91 303.6 0.0 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 KOS17693.1 - 9.3e-59 197.6 1.7 1.7e-58 196.8 1.2 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KOS17693.1 - 2.3e-22 79.2 0.0 1.4e-21 76.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS17693.1 - 2.1e-07 30.6 0.0 5.9e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS17693.1 - 0.0042 16.9 0.0 0.053 13.3 0.0 2.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 KOS17693.1 - 0.01 14.7 0.0 0.022 13.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Daxx PF03344.10 KOS17693.1 - 0.21 10.0 9.8 0.29 9.5 6.8 1.2 1 0 0 1 1 1 0 Daxx Family GOLD_2 PF13897.1 KOS17693.1 - 0.22 11.7 1.1 33 4.7 0.7 2.8 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DUF2407_C PF13373.1 KOS17694.1 - 1.9e-30 105.6 0.0 2.7e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 KOS17694.1 - 1.9e-24 85.6 0.0 2.8e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Mito_fiss_reg PF05308.6 KOS17694.1 - 0.014 14.7 0.5 0.014 14.7 0.3 2.4 2 1 0 2 2 2 0 Mitochondrial fission regulator ubiquitin PF00240.18 KOS17694.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family TMEM171 PF15471.1 KOS17694.1 - 0.49 9.1 2.2 0.98 8.1 1.5 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 PPR_2 PF13041.1 KOS17695.1 - 5.8e-18 64.6 0.3 6.6e-05 22.8 0.0 5.4 4 1 1 5 5 5 4 PPR repeat family PPR_3 PF13812.1 KOS17695.1 - 3e-16 58.2 2.9 0.0041 17.2 0.0 6.7 7 0 0 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.15 KOS17695.1 - 8e-13 47.4 3.3 0.00063 19.5 0.0 6.0 6 0 0 6 6 6 3 PPR repeat PPR_1 PF12854.2 KOS17695.1 - 0.025 14.0 4.6 4.9 6.7 0.1 4.4 4 0 0 4 4 4 0 PPR repeat COX7C PF02935.11 KOS17696.1 - 7e-17 60.9 0.4 8.3e-17 60.7 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc DUF2416 PF10315.4 KOS17697.1 - 9.9e-05 22.5 0.4 0.0051 17.0 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2416) Zn_clus PF00172.13 KOS17698.1 - 8.5e-07 28.7 9.1 1.2e-06 28.2 6.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gly-zipper_YMGG PF13441.1 KOS17698.1 - 0.06 12.8 8.2 0.16 11.5 5.7 1.7 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 KOS17698.1 - 0.2 11.3 10.1 0.42 10.2 7.0 1.5 1 0 0 1 1 1 0 Glycine zipper Ima1_N PF09779.4 KOS17699.1 - 2.1e-39 135.0 2.7 3.4e-39 134.3 1.8 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.2 KOS17699.1 - 0.057 13.2 2.5 1.7 8.4 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 KOS17699.1 - 1.1 8.9 4.9 0.29 10.8 1.1 1.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Y_phosphatase2 PF03162.8 KOS17700.1 - 6.6e-44 149.1 0.0 9.7e-44 148.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KOS17700.1 - 1.3e-10 41.7 0.0 6.7e-08 32.9 0.0 2.2 1 1 1 2 2 2 2 Tyrosine phosphatase family Y_phosphatase PF00102.22 KOS17700.1 - 0.0078 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KOS17700.1 - 0.0082 15.7 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pho88 PF10032.4 KOS17701.1 - 4e-81 270.8 0.5 4.5e-81 270.6 0.3 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DAO PF01266.19 KOS17702.1 - 1.6e-12 47.0 5.4 5.4e-12 45.2 0.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KOS17702.1 - 0.022 14.8 0.0 6.8 6.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CP12 PF02672.10 KOS17703.1 - 0.0051 17.2 1.9 0.012 16.1 1.3 1.5 1 0 0 1 1 1 1 CP12 domain TPR_11 PF13414.1 KOS17704.1 - 6.5e-07 28.9 10.7 0.0055 16.3 0.3 3.5 3 0 0 3 3 3 3 TPR repeat Apc3 PF12895.2 KOS17704.1 - 0.027 14.6 2.9 0.064 13.4 2.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KOS17704.1 - 0.044 13.4 7.5 2.4 7.9 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KOS17704.1 - 0.095 12.6 8.6 0.61 10.1 0.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HIT PF01230.18 KOS17705.1 - 2.9e-19 69.4 0.0 4.6e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KOS17705.1 - 2.6e-05 24.4 0.0 4.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KOS17705.1 - 0.25 11.0 0.8 2.2 7.9 0.1 2.5 2 1 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 G-alpha PF00503.15 KOS17706.1 - 1.2e-106 356.7 3.3 2.9e-104 348.8 2.3 2.0 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KOS17706.1 - 9.3e-12 44.5 0.3 3.2e-10 39.5 0.1 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family DUF1287 PF06940.6 KOS17706.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) Miro PF08477.8 KOS17706.1 - 0.11 13.0 0.1 9.7 6.7 0.0 2.7 3 0 0 3 3 3 0 Miro-like protein IGR PF09597.5 KOS17707.1 - 1.8e-23 82.2 0.0 2.5e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 IGR protein motif Mid1 PF12929.2 KOS17708.1 - 1.1e-121 406.5 0.1 1.3e-121 406.3 0.1 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KOS17708.1 - 0.12 12.7 2.7 2.1 8.7 0.3 2.4 2 0 0 2 2 2 0 Fz domain MFS_1 PF07690.11 KOS17709.1 - 2.3e-23 82.5 33.7 6.6e-23 80.9 23.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_92 PF07971.7 KOS17711.1 - 4.6e-163 543.4 0.0 5.7e-163 543.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 SLT PF01464.15 KOS17712.1 - 0.0012 18.3 2.5 0.0054 16.2 1.7 1.9 1 1 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.1 KOS17712.1 - 0.0034 16.8 0.5 0.0057 16.1 0.3 1.4 1 0 0 1 1 1 1 Lysozyme-like NAD_binding_4 PF07993.7 KOS17713.1 - 3.5e-31 108.0 0.0 1.4e-30 106.0 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 KOS17713.1 - 5.5e-30 104.0 0.0 1e-29 103.1 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KOS17713.1 - 4.6e-11 42.6 0.0 8.7e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KOS17713.1 - 1.8e-06 27.0 0.1 5.6e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain PP-binding PF00550.20 KOS17713.1 - 3.5e-05 23.9 0.2 0.00011 22.3 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KOS17713.1 - 0.0071 16.2 0.3 0.054 13.4 0.1 2.4 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KOS17713.1 - 0.02 13.6 0.0 0.073 11.7 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KOS17713.1 - 0.065 12.8 0.1 0.51 9.9 0.0 2.5 3 0 0 3 3 3 0 KR domain Polysacc_synt_2 PF02719.10 KOS17713.1 - 0.34 9.7 0.2 1.2 7.9 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sugar_tr PF00083.19 KOS17714.1 - 8.8e-121 403.6 19.8 1.2e-120 403.1 13.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS17714.1 - 8.2e-26 90.5 27.9 1.7e-19 69.7 6.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lysis_S PF04971.7 KOS17714.1 - 0.0045 16.6 0.1 0.014 15.1 0.1 1.8 1 0 0 1 1 1 1 Lysis protein S YrhC PF14143.1 KOS17714.1 - 0.75 9.7 3.1 28 4.7 0.0 3.6 3 0 0 3 3 3 0 YrhC-like protein HEAT_2 PF13646.1 KOS17715.1 - 2.5e-31 107.7 11.2 5.4e-16 58.6 0.2 3.6 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.11 KOS17715.1 - 2.6e-19 67.6 11.1 0.019 15.4 0.2 6.6 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 KOS17715.1 - 1.9e-07 31.3 14.6 0.0022 18.4 0.0 4.7 3 2 1 4 4 4 3 HEAT-like repeat HEAT PF02985.17 KOS17715.1 - 1.7e-06 27.5 5.9 0.0069 16.3 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat Arm PF00514.18 KOS17715.1 - 0.018 14.8 0.5 3.7 7.5 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DEP PF00610.16 KOS17716.1 - 8.3e-27 92.7 0.1 1.7e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cation_efflux PF01545.16 KOS17717.1 - 1.3e-31 109.7 1.2 1.6e-31 109.4 0.8 1.0 1 0 0 1 1 1 1 Cation efflux family Glyco_transf_28 PF03033.15 KOS17718.1 - 0.001 18.8 1.1 0.0021 17.8 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KOS17718.1 - 0.0045 15.5 0.0 0.014 13.9 0.0 1.7 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Fungal_trans_2 PF11951.3 KOS17721.1 - 3.1e-38 131.4 0.0 4.1e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AT_hook PF02178.14 KOS17721.1 - 0.045 13.4 5.0 0.15 11.8 3.5 1.9 1 0 0 1 1 1 0 AT hook motif HTH_30 PF13556.1 KOS17721.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain SR-25 PF10500.4 KOS17722.1 - 0.16 11.4 15.0 0.083 12.3 3.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MIP-T3 PF10243.4 KOS17722.1 - 0.17 10.3 14.2 0.21 10.0 9.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 YqfQ PF14181.1 KOS17722.1 - 3.9 7.5 8.4 1.9 8.5 2.5 2.1 2 0 0 2 2 2 0 YqfQ-like protein Arch_ATPase PF01637.13 KOS17724.1 - 3.7e-08 33.3 0.1 5.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 KOS17724.1 - 0.0001 22.3 0.3 0.0066 16.4 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KOS17724.1 - 0.0077 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 KOS17724.1 - 0.014 15.9 0.1 1.4 9.4 0.0 2.9 2 1 0 2 2 2 0 Miro-like protein AAA_25 PF13481.1 KOS17724.1 - 0.029 13.7 0.1 0.12 11.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 KOS17724.1 - 0.033 13.0 0.0 0.068 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DAP3 PF10236.4 KOS17724.1 - 0.054 12.4 0.2 0.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DNA_pol3_delta PF06144.8 KOS17724.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Gtr1_RagA PF04670.7 KOS17724.1 - 0.11 11.6 0.1 2.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KOS17724.1 - 0.11 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Myb_DNA-bind_6 PF13921.1 KOS17725.1 - 6.6e-14 51.7 4.1 1.1e-10 41.4 0.1 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KOS17725.1 - 1e-12 47.8 1.2 7.2e-09 35.5 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Dicty_REP PF05086.7 KOS17725.1 - 1.3 6.7 1.8 2.4 5.7 1.2 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein p450 PF00067.17 KOS17726.1 - 1.6e-18 66.4 0.0 2.9e-17 62.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.18 KOS17727.1 - 1e-35 123.4 12.8 1.4e-35 123.0 8.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KOS17727.1 - 4.3e-34 117.7 0.0 2.3e-33 115.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KOS17727.1 - 6.2e-07 29.6 0.0 0.0078 16.2 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 KOS17727.1 - 2.3e-06 27.7 0.0 9.1e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 KOS17727.1 - 4.7e-05 22.7 0.0 0.0065 15.7 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KOS17727.1 - 0.00011 23.0 0.0 0.00032 21.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KOS17727.1 - 0.00042 19.5 0.0 0.00073 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 KOS17727.1 - 0.00054 19.8 0.0 0.0033 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KOS17727.1 - 0.00059 19.9 0.0 0.0029 17.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KOS17727.1 - 0.0022 17.5 0.0 0.01 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 KOS17727.1 - 0.0023 17.4 0.0 0.0064 15.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 KOS17727.1 - 0.0064 16.6 0.0 0.05 13.7 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 KOS17727.1 - 0.0074 15.8 0.2 0.017 14.6 0.0 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 KOS17727.1 - 0.01 15.2 0.2 0.044 13.1 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KOS17727.1 - 0.011 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KOS17727.1 - 0.012 15.5 0.4 0.17 11.8 0.3 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 KOS17727.1 - 0.015 15.2 0.0 0.067 13.1 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 KOS17727.1 - 0.019 14.6 0.0 0.059 13.0 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KOS17727.1 - 0.02 15.2 0.0 0.063 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KOS17727.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KOS17727.1 - 0.072 13.5 0.0 0.2 12.1 0.0 1.7 2 0 0 2 2 1 0 Miro-like protein Zeta_toxin PF06414.7 KOS17727.1 - 0.078 12.0 0.0 0.17 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 KOS17727.1 - 0.079 12.6 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 1 0 NACHT domain DUF1016 PF06250.6 KOS17727.1 - 0.087 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1016) Rad17 PF03215.10 KOS17727.1 - 0.12 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 KOS17727.1 - 0.17 12.2 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Erf4 PF10256.4 KOS17728.1 - 3.5e-27 94.6 0.0 4.7e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family OmpH PF03938.9 KOS17729.1 - 0.00022 21.1 3.1 0.00022 21.1 2.2 2.0 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) BolA PF01722.13 KOS17730.1 - 3.1e-28 97.5 0.4 4.1e-28 97.1 0.3 1.2 1 0 0 1 1 1 1 BolA-like protein AMP-binding PF00501.23 KOS17731.1 - 5e-67 226.1 0.0 9e-67 225.2 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS17731.1 - 1.4e-11 45.1 0.0 3e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PIP5K PF01504.13 KOS17732.1 - 2.8e-58 197.0 0.1 5.3e-58 196.0 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KOS17732.1 - 3.7e-26 91.8 0.0 5.9e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KOS17732.1 - 1.2e-14 53.8 7.0 1.2e-14 53.8 4.9 1.9 2 0 0 2 2 2 1 FYVE zinc finger HMGL-like PF00682.14 KOS17734.1 - 2.3e-69 233.6 1.5 3.7e-69 232.9 1.0 1.3 1 0 0 1 1 1 1 HMGL-like Trp_syntA PF00290.15 KOS17734.1 - 0.039 12.4 0.0 6.3 5.2 0.0 2.5 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Pol_alpha_B_N PF08418.5 KOS17734.1 - 0.067 12.7 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RHS PF03527.9 KOS17735.1 - 0.34 10.7 2.4 0.93 9.3 1.6 1.7 1 1 0 1 1 1 0 RHS protein IF4E PF01652.13 KOS17736.1 - 3.1e-59 199.2 0.0 3.8e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E UMP1 PF05348.6 KOS17738.1 - 2.7e-23 82.3 0.0 4.5e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 ABC_tran PF00005.22 KOS17739.1 - 2e-21 76.7 0.0 1.9e-10 41.1 0.0 3.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KOS17739.1 - 2.1e-10 41.0 0.1 0.002 18.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KOS17739.1 - 1e-08 36.0 0.0 0.00047 20.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KOS17739.1 - 4e-06 27.2 0.0 0.093 13.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KOS17739.1 - 6.7e-06 25.5 0.0 0.085 12.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 KOS17739.1 - 1.1e-05 25.3 0.1 0.081 12.8 0.1 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KOS17739.1 - 2.9e-05 24.1 0.2 0.013 15.4 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KOS17739.1 - 8.2e-05 22.0 0.3 2 7.7 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 KOS17739.1 - 0.00015 21.9 0.0 1.4 9.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KOS17739.1 - 0.00023 21.0 0.0 0.15 11.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KOS17739.1 - 0.0011 19.2 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KOS17739.1 - 0.0014 18.6 0.0 0.85 9.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KOS17739.1 - 0.008 15.6 0.0 3 7.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_14 PF13173.1 KOS17739.1 - 0.011 15.6 0.0 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KOS17739.1 - 0.024 15.1 0.0 6 7.4 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein SMC_N PF02463.14 KOS17739.1 - 0.025 13.8 0.0 3.4 6.8 0.1 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 KOS17739.1 - 0.027 13.9 0.0 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.9 KOS17739.1 - 0.028 14.1 0.1 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KOS17739.1 - 0.039 13.4 0.0 0.41 10.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KOS17739.1 - 0.06 12.8 0.1 3.9 6.9 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 KOS17739.1 - 0.086 13.0 0.0 13 5.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 KOS17739.1 - 0.11 12.7 0.1 3.9 7.6 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KOS17739.1 - 0.12 11.9 0.0 17 5.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 KOS17739.1 - 0.14 11.7 0.0 8 5.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 KOS17739.1 - 0.17 11.3 0.0 3.3 7.1 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 KOS17739.1 - 0.19 10.8 0.0 8.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_15 PF13175.1 KOS17739.1 - 0.22 10.5 0.0 14 4.5 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain NTPase_1 PF03266.10 KOS17739.1 - 0.26 10.9 0.1 57 3.3 0.0 3.0 3 0 0 3 3 3 0 NTPase AAA_13 PF13166.1 KOS17739.1 - 0.3 9.5 0.1 0.43 8.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain Lactonase PF10282.4 KOS17740.1 - 2.5e-81 273.4 0.0 3.5e-81 272.9 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PEMT PF04191.8 KOS17741.1 - 6.4e-57 190.1 9.3 1.6e-35 121.3 0.7 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase eIF3g PF12353.3 KOS17742.1 - 1.7e-45 154.0 1.9 2.7e-45 153.4 1.3 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KOS17742.1 - 5.2e-15 54.8 0.1 1.2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS17742.1 - 4.1e-12 45.8 0.1 1e-11 44.6 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS17742.1 - 2e-07 30.7 0.7 4.5e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF202 PF02656.10 KOS17744.1 - 3.2e-19 68.9 1.6 1.3e-18 66.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2910 PF11139.3 KOS17744.1 - 0.055 12.5 0.2 0.069 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) zf-LITAF-like PF10601.4 KOS17744.1 - 0.055 13.3 0.0 3.1 7.7 0.2 2.8 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain 2TM PF13239.1 KOS17744.1 - 0.43 10.6 0.1 0.43 10.6 0.0 2.0 2 1 0 2 2 2 0 2TM domain COX4_pro_2 PF07835.7 KOS17744.1 - 1 9.3 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF676 PF05057.9 KOS17746.1 - 2.7e-41 141.2 0.0 1.3e-26 93.2 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) PGAP1 PF07819.8 KOS17746.1 - 0.026 14.1 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 KOS17746.1 - 0.06 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.6 KOS17746.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LRS4 PF10422.4 KOS17746.1 - 0.84 8.9 9.4 0.061 12.6 0.4 2.7 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 NTR2 PF15458.1 KOS17748.1 - 5.2e-71 238.8 20.8 5.2e-71 238.8 14.4 1.6 2 0 0 2 2 2 1 Nineteen complex-related protein 2 AIF_C PF14721.1 KOS17748.1 - 6.6 6.9 8.2 0.16 12.2 0.2 2.3 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Ctr PF04145.10 KOS17749.1 - 3.3e-41 140.7 0.5 7.9e-41 139.4 0.4 1.6 1 1 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 KOS17749.1 - 0.068 12.6 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) YfhO PF09586.5 KOS17749.1 - 1.6 6.6 5.1 2.3 6.1 3.5 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO 2OG-FeII_Oxy_2 PF13532.1 KOS17750.1 - 0.0024 17.7 0.0 0.35 10.6 0.0 2.1 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Ank_5 PF13857.1 KOS17751.1 - 9.3e-20 70.2 9.0 3.1e-09 36.7 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KOS17751.1 - 4.4e-19 68.6 0.3 9.4e-19 67.5 0.2 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KOS17751.1 - 2.8e-18 64.7 2.2 1.4e-08 34.1 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KOS17751.1 - 3.1e-17 62.5 3.9 1.3e-08 35.1 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS17751.1 - 9.1e-15 53.3 0.1 5.6e-06 26.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Zip PF02535.17 KOS17752.1 - 1.7e-47 162.0 9.1 5.5e-47 160.3 6.3 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter HXXEE PF13787.1 KOS17752.1 - 0.092 13.1 5.0 45 4.4 0.0 3.4 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif Sdh_cyt PF01127.17 KOS17752.1 - 1.5 8.6 8.1 0.29 10.9 0.1 3.0 2 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Steroid_dh PF02544.11 KOS17753.1 - 2.4e-15 56.5 2.6 4.8e-15 55.6 1.8 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF2910 PF11139.3 KOS17753.1 - 0.48 9.5 6.5 0.76 8.8 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) LSM PF01423.17 KOS17754.1 - 1.1e-18 66.5 0.6 1.2e-18 66.3 0.4 1.0 1 0 0 1 1 1 1 LSM domain Sec23_trunk PF04811.10 KOS17755.1 - 1.3e-50 172.0 0.0 3.6e-50 170.6 0.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KOS17755.1 - 8.5e-22 76.5 0.0 1.7e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KOS17755.1 - 1.7e-17 63.7 0.0 2.7e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KOS17755.1 - 1.8e-17 62.5 5.6 4.4e-17 61.3 3.9 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KOS17755.1 - 7.8e-08 31.8 0.0 1.6e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat PTA_PTB PF01515.14 KOS17755.1 - 0.083 11.9 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Phosphate acetyl/butaryl transferase Linker_histone PF00538.14 KOS17756.1 - 1e-24 86.4 0.2 2.6e-24 85.1 0.1 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family DEAD PF00270.24 KOS17758.1 - 7.6e-42 142.6 0.0 1.1e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS17758.1 - 3.3e-24 84.5 0.1 6.4e-24 83.6 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KOS17758.1 - 0.1 11.6 0.0 0.24 10.4 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit GRP PF07172.6 KOS17758.1 - 1.3 9.5 12.7 2.4 8.6 8.8 1.4 1 0 0 1 1 1 0 Glycine rich protein family Gti1_Pac2 PF09729.4 KOS17759.1 - 3.9e-49 166.7 1.6 1.6e-46 158.2 1.1 2.3 1 1 0 1 1 1 1 Gti1/Pac2 family tRNA-synt_2 PF00152.15 KOS17760.1 - 4.1e-71 239.5 0.0 4.8e-70 235.9 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KOS17760.1 - 0.00044 20.0 0.0 0.00077 19.2 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KOS17760.1 - 0.1 11.7 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DASH_Spc19 PF08287.6 KOS17760.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Spc19 DUF2263 PF10021.4 KOS17761.1 - 4.1e-12 46.3 0.0 7.3e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Pox_Ag35 PF03286.9 KOS17762.1 - 0.085 12.3 3.0 0.086 12.3 2.1 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nucleoplasmin PF03066.10 KOS17762.1 - 0.26 10.7 7.2 0.28 10.6 5.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin PPP4R2 PF09184.6 KOS17762.1 - 0.54 9.7 4.5 0.56 9.7 3.1 1.0 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.7 KOS17762.1 - 0.87 8.7 3.4 0.9 8.7 2.4 1.0 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 KOS17762.1 - 2.4 7.7 7.3 2.4 7.7 5.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 KOS17762.1 - 3.9 5.3 4.9 3.9 5.4 3.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.2 KOS17763.1 - 1.4e-22 79.8 3.3 2.6e-13 50.1 1.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KOS17763.1 - 1.7e-17 62.2 11.1 6e-06 25.8 0.3 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KOS17763.1 - 5.8e-12 45.7 10.1 3.4e-06 27.4 0.3 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KOS17763.1 - 8.6e-12 44.9 12.4 5.2e-05 23.3 0.3 4.4 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS17763.1 - 9.1e-11 40.9 7.9 0.00012 21.9 0.2 4.1 5 0 0 5 5 5 3 Ankyrin repeat DUF3487 PF11990.3 KOS17763.1 - 0.061 12.7 1.7 0.11 11.8 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) NicO PF03824.11 KOS17763.1 - 0.38 10.0 7.7 0.29 10.3 4.6 1.3 1 1 0 1 1 1 0 High-affinity nickel-transport protein DUF4191 PF13829.1 KOS17763.1 - 1 8.4 5.2 1.9 7.5 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DHHW PF14286.1 KOS17764.1 - 0.39 9.9 3.0 0.5 9.6 2.1 1.1 1 0 0 1 1 1 0 DHHW protein Hid1 PF12722.2 KOS17764.1 - 3.5 5.1 4.6 4.2 4.9 3.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAD_binding_3 PF01494.14 KOS17765.1 - 2.9e-12 46.3 2.3 2.2e-06 26.9 0.2 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KOS17765.1 - 5.6e-05 22.2 0.1 0.00016 20.6 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KOS17765.1 - 9.1e-05 22.4 0.1 0.00026 20.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 KOS17765.1 - 0.00032 20.1 0.0 0.00055 19.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KOS17765.1 - 0.0069 16.3 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_2 PF00890.19 KOS17765.1 - 0.023 13.5 0.1 0.043 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KOS17765.1 - 0.03 14.2 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS17765.1 - 0.036 14.4 0.0 0.085 13.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KOS17765.1 - 0.058 12.9 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KOS17765.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3140 PF11338.3 KOS17766.1 - 1.2e-29 102.2 0.5 1.2e-29 102.2 0.4 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF3140) DUF2945 PF11160.3 KOS17766.1 - 0.002 17.8 0.2 0.0085 15.8 0.2 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) Nop14 PF04147.7 KOS17766.1 - 0.013 13.5 36.2 0.017 13.1 25.1 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 KOS17766.1 - 0.031 13.3 33.8 0.044 12.8 23.4 1.2 1 0 0 1 1 1 0 BUD22 DUF4213 PF13938.1 KOS17766.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4213) CENP-T PF15511.1 KOS17766.1 - 0.24 10.5 18.5 0.28 10.3 12.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ribosomal_L19e PF01280.15 KOS17766.1 - 2 8.1 9.4 1.5 8.6 1.8 2.3 2 0 0 2 2 2 0 Ribosomal protein L19e Sugar_tr PF00083.19 KOS17767.1 - 1e-64 218.8 12.3 1.2e-64 218.6 8.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS17767.1 - 3.8e-08 32.4 27.4 1.1e-05 24.2 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.22 KOS17768.1 - 7e-51 172.1 0.0 1.4e-24 86.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 KOS17768.1 - 5.3e-48 162.9 30.8 1.2e-27 96.5 3.4 3.0 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.1 KOS17768.1 - 1.8e-19 70.8 0.0 0.0012 18.9 0.0 4.1 4 0 0 4 4 4 4 AAA domain AAA_16 PF13191.1 KOS17768.1 - 6.3e-11 42.5 2.9 4.2e-05 23.6 0.4 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KOS17768.1 - 2e-10 40.3 1.2 1.5e-06 27.7 0.0 3.4 5 0 0 5 5 3 2 AAA domain SMC_N PF02463.14 KOS17768.1 - 8.1e-09 35.0 0.9 0.0021 17.3 0.0 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KOS17768.1 - 1.2e-08 34.2 0.0 0.002 17.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KOS17768.1 - 4.5e-08 32.5 1.6 0.0073 15.8 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KOS17768.1 - 1.1e-07 32.0 0.3 0.029 14.4 0.0 3.1 3 2 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KOS17768.1 - 1.7e-07 32.0 0.2 0.015 16.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 KOS17768.1 - 1.9e-07 30.7 2.0 0.00058 19.5 0.3 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_28 PF13521.1 KOS17768.1 - 2.6e-07 30.7 0.5 0.004 17.1 0.1 3.0 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KOS17768.1 - 3.1e-07 30.0 0.1 0.0013 18.2 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family NACHT PF05729.7 KOS17768.1 - 5.5e-07 29.3 0.0 0.009 15.6 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.1 KOS17768.1 - 2.3e-06 28.0 6.6 0.0018 18.6 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 KOS17768.1 - 5.3e-06 26.0 0.6 0.011 15.2 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_30 PF13604.1 KOS17768.1 - 1.6e-05 24.6 0.5 0.07 12.6 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 KOS17768.1 - 1.6e-05 25.2 0.0 0.1 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 KOS17768.1 - 2e-05 24.1 0.7 0.095 12.1 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 KOS17768.1 - 3.6e-05 22.8 0.2 0.18 10.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Arch_ATPase PF01637.13 KOS17768.1 - 4.1e-05 23.3 0.1 0.072 12.7 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase AAA_15 PF13175.1 KOS17768.1 - 0.00016 20.8 0.0 1.9 7.4 0.0 3.7 4 0 0 4 4 4 1 AAA ATPase domain AAA_33 PF13671.1 KOS17768.1 - 0.00021 21.1 0.1 0.47 10.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KOS17768.1 - 0.00025 20.7 0.2 0.4 10.3 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KOS17768.1 - 0.00033 20.4 0.6 0.19 11.3 0.1 3.2 4 0 0 4 4 3 1 NTPase SbcCD_C PF13558.1 KOS17768.1 - 0.00033 20.5 0.3 0.63 10.0 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KOS17768.1 - 0.00062 20.2 0.1 1.3 9.5 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein RNA_helicase PF00910.17 KOS17768.1 - 0.00082 19.5 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.18 KOS17768.1 - 0.0013 18.6 1.2 0.54 10.2 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.24 KOS17768.1 - 0.003 17.7 0.1 1.7 8.8 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KOS17768.1 - 0.0055 16.3 0.5 3.1 7.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 KOS17768.1 - 0.0063 16.0 0.3 1.3 8.4 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein DUF2075 PF09848.4 KOS17768.1 - 0.0066 15.4 0.1 0.22 10.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 KOS17768.1 - 0.0075 15.9 0.7 10 5.8 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.4 KOS17768.1 - 0.011 14.3 0.4 0.4 9.2 0.1 2.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_14 PF13173.1 KOS17768.1 - 0.014 15.3 0.1 6.5 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 KOS17768.1 - 0.015 14.6 0.8 0.54 9.5 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein IstB_IS21 PF01695.12 KOS17768.1 - 0.022 14.1 1.1 2.9 7.2 0.0 3.3 4 0 0 4 4 3 0 IstB-like ATP binding protein PduV-EutP PF10662.4 KOS17768.1 - 0.038 13.4 0.4 6.9 6.1 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 KOS17768.1 - 0.05 12.6 0.1 1 8.3 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_24 PF13479.1 KOS17768.1 - 0.069 12.7 5.3 2.2 7.7 0.0 2.6 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.17 KOS17768.1 - 0.1 12.0 0.4 3.8 6.9 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 KOS17768.1 - 0.11 12.0 0.1 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SRPRB PF09439.5 KOS17768.1 - 0.12 11.5 0.1 13 4.9 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PhoH PF02562.11 KOS17768.1 - 0.21 10.8 0.1 5.1 6.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein ATP-synt_ab PF00006.20 KOS17768.1 - 0.21 11.0 0.0 3.7 6.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 KOS17768.1 - 0.28 10.2 1.2 10 5.1 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 KOS17768.1 - 0.31 10.8 1.0 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Dynamin family TrwB_AAD_bind PF10412.4 KOS17768.1 - 0.42 9.1 0.2 1.4 7.4 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PRK PF00485.13 KOS17768.1 - 0.47 9.9 3.1 3 7.3 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.9 KOS17768.1 - 0.6 9.0 0.0 25 3.6 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Col_cuticle_N PF01484.12 KOS17768.1 - 2.9 7.6 6.5 6.9 6.4 3.3 2.6 2 0 0 2 2 1 0 Nematode cuticle collagen N-terminal domain DUF87 PF01935.12 KOS17768.1 - 3.4 7.4 2.8 1.5 8.6 0.2 1.6 2 0 0 2 2 1 0 Domain of unknown function DUF87 Amidohydro_1 PF01979.15 KOS17771.1 - 3.6e-22 79.4 0.2 6.3e-11 42.4 0.0 3.2 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_4 PF13147.1 KOS17771.1 - 1.8e-19 70.8 11.9 7.8e-13 49.0 5.8 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KOS17771.1 - 3.5e-10 39.5 0.7 7.2e-10 38.5 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KOS17771.1 - 1.2e-06 27.9 6.3 0.00018 20.8 0.0 3.1 2 1 0 3 3 3 2 Amidohydrolase family polyprenyl_synt PF00348.12 KOS17772.1 - 2.6e-53 180.5 0.0 4.8e-50 169.8 0.0 2.0 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 KOS17772.1 - 0.022 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Cys_Met_Meta_PP PF01053.15 KOS17773.1 - 1.4e-38 132.1 0.0 1.8e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KOS17773.1 - 0.007 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pterin_bind PF00809.17 KOS17774.1 - 1.3e-62 210.9 0.0 2.7e-62 209.8 0.0 1.5 2 0 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 KOS17774.1 - 5.8e-33 113.3 0.0 1.1e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.10 KOS17775.1 - 1.7e-69 234.4 1.1 4.1e-69 233.2 0.8 1.6 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KOS17775.1 - 2.2e-08 33.4 0.0 2.2e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KOS17775.1 - 6.8e-06 25.1 3.6 1.1e-05 24.5 2.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KOS17775.1 - 0.012 14.5 1.0 0.02 13.8 0.7 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.16 KOS17775.1 - 0.013 14.4 0.1 0.021 13.7 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NanE PF04131.9 KOS17775.1 - 0.034 13.1 0.1 0.098 11.6 0.1 1.7 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase TIM21 PF08294.6 KOS17776.1 - 6.6e-44 149.0 0.0 8.8e-44 148.6 0.0 1.2 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 KOS17776.1 - 0.00069 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 MFS_1 PF07690.11 KOS17777.1 - 2.4e-38 131.7 48.5 3.5e-38 131.2 31.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KOS17777.1 - 2.3e-13 49.2 19.4 3.6e-13 48.5 13.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ArfGap PF01412.13 KOS17778.1 - 4.4e-05 23.2 0.4 0.00012 21.8 0.3 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3275 PF11679.3 KOS17778.1 - 4.3 6.9 17.1 0.029 14.0 2.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3275) ArfGap PF01412.13 KOS17779.1 - 3.3e-25 88.1 0.2 3.6e-25 87.9 0.1 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-B_box PF00643.19 KOS17779.1 - 0.042 13.7 1.9 3.7 7.5 0.1 2.1 2 0 0 2 2 2 0 B-box zinc finger Cas_CXXC_CXXC PF09706.5 KOS17779.1 - 0.078 13.1 1.3 6.3 7.0 0.1 2.2 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) DNA_RNApol_7kD PF03604.8 KOS17779.1 - 0.13 11.7 0.7 15 5.1 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-UBR PF02207.15 KOS17779.1 - 0.14 11.9 1.1 0.38 10.5 0.8 1.7 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) CDC27 PF09507.5 KOS17780.1 - 0.11 11.7 13.0 0.14 11.3 9.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Tachystatin_B PF11478.3 KOS17780.1 - 0.54 10.0 4.2 1.3 8.7 2.9 1.6 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B Herpes_UL32 PF06070.6 KOS17780.1 - 0.91 7.8 16.8 1 7.7 11.6 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Macoilin PF09726.4 KOS17780.1 - 2.1 6.5 19.7 2.4 6.3 13.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Plasmodium_Vir PF05795.6 KOS17780.1 - 2.4 7.2 8.5 3.5 6.7 5.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ACBP PF00887.14 KOS17781.1 - 4.6e-22 77.4 1.2 5.2e-22 77.3 0.9 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein zf-H2C2_2 PF13465.1 KOS17782.1 - 1.1e-07 31.7 26.7 4e-06 26.8 2.4 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KOS17782.1 - 4.3e-05 23.6 13.6 0.0012 19.0 2.9 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS17782.1 - 0.0023 18.1 12.3 0.0061 16.8 0.9 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger Bromodomain PF00439.20 KOS17783.1 - 1.1e-16 60.4 0.0 2e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain DEAD PF00270.24 KOS17784.1 - 6.6e-40 136.3 0.6 9.4e-40 135.8 0.4 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS17784.1 - 2e-20 72.4 0.1 4.1e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS17784.1 - 0.061 13.1 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit WD40 PF00400.27 KOS17785.1 - 3e-29 99.7 12.0 1.5e-09 37.3 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF3639 PF12341.3 KOS17785.1 - 0.063 13.2 0.1 0.66 10.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) 2OG-FeII_Oxy_2 PF13532.1 KOS17786.1 - 4.3e-35 121.3 0.0 5.6e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 KOS17786.1 - 4.9e-09 35.9 5.9 1e-08 34.9 4.1 1.5 1 0 0 1 1 1 1 GRF zinc finger RibD_C PF01872.12 KOS17787.1 - 5e-35 120.9 0.0 5.8e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain PfkB PF00294.19 KOS17788.1 - 2.5e-53 181.1 0.2 3e-53 180.9 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CHAT PF12770.2 KOS17788.1 - 0.005 16.0 1.0 0.023 13.8 0.7 1.8 1 1 0 1 1 1 1 CHAT domain UQ_con PF00179.21 KOS17789.1 - 1.8e-08 33.8 0.6 4.3e-08 32.7 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PAT1 PF09770.4 KOS17789.1 - 0.042 12.1 9.0 0.046 11.9 6.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RWD PF05773.17 KOS17789.1 - 0.076 12.9 1.5 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 RWD domain Suf PF05843.9 KOS17789.1 - 0.49 10.0 4.3 0.66 9.6 3.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 KOS17789.1 - 1.8 8.6 8.5 0.9 9.5 1.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4106 PF13388.1 KOS17789.1 - 4.9 6.0 13.8 6.1 5.6 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) PIH1 PF08190.7 KOS17789.1 - 8.9 5.6 11.8 6.4 6.1 3.8 2.0 2 0 0 2 2 2 0 pre-RNA processing PIH1/Nop17 Totivirus_coat PF05518.6 KOS17789.1 - 9.6 3.8 15.3 1.1 7.0 3.2 2.0 2 0 0 2 2 2 0 Totivirus coat protein DUF1014 PF06244.7 KOS17790.1 - 1.6e-23 83.1 9.5 4.5e-23 81.7 6.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) SPATIAL PF15256.1 KOS17790.1 - 8.1 6.4 7.5 44 4.0 3.4 2.1 2 0 0 2 2 2 0 SPATIAL MFS_1 PF07690.11 KOS17791.1 - 1.1e-37 129.5 11.3 1.1e-37 129.5 7.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS17791.1 - 4.1e-12 45.4 2.6 4.1e-12 45.4 1.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KOS17791.1 - 0.00032 19.2 2.1 0.00032 19.2 1.4 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Nuc_H_symport PF03825.11 KOS17791.1 - 0.0028 16.4 1.1 0.0028 16.4 0.8 1.9 2 0 0 2 2 2 1 Nucleoside H+ symporter DUF1510 PF07423.6 KOS17792.1 - 7.6e-08 31.9 17.3 8.8e-08 31.7 12.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) IncA PF04156.9 KOS17792.1 - 1.4e-06 28.0 13.7 1.6e-06 27.8 9.5 1.0 1 0 0 1 1 1 1 IncA protein SpoIIIAH PF12685.2 KOS17792.1 - 2.8e-06 26.9 10.5 3.8e-06 26.5 7.3 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein Zip PF02535.17 KOS17792.1 - 0.00017 20.6 2.7 0.00021 20.4 1.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter TRAP_alpha PF03896.11 KOS17792.1 - 0.00043 19.3 4.9 0.00053 19.0 3.4 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SID-1_RNA_chan PF13965.1 KOS17792.1 - 0.0017 16.6 7.5 0.0019 16.4 5.2 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Mem_trans PF03547.13 KOS17792.1 - 0.0027 16.0 7.2 0.0031 15.8 5.0 1.0 1 0 0 1 1 1 1 Membrane transport protein Ycf1 PF05758.7 KOS17792.1 - 0.0061 14.3 22.6 0.0073 14.0 15.7 1.0 1 0 0 1 1 1 1 Ycf1 RIC3 PF15361.1 KOS17792.1 - 0.014 15.6 16.9 0.018 15.2 11.7 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Folate_carrier PF01770.13 KOS17792.1 - 0.015 13.8 11.1 0.019 13.5 7.7 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF1183 PF06682.7 KOS17792.1 - 0.016 14.8 5.7 0.02 14.4 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Tetraspannin PF00335.15 KOS17792.1 - 0.017 14.3 0.5 0.025 13.8 0.3 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF4446 PF14584.1 KOS17792.1 - 0.022 14.5 12.6 0.028 14.2 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Serinc PF03348.10 KOS17792.1 - 0.039 12.6 13.5 0.051 12.2 9.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF913 PF06025.7 KOS17792.1 - 0.044 12.5 13.6 0.051 12.3 9.4 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tmp39 PF10271.4 KOS17792.1 - 0.048 12.3 2.7 0.057 12.0 1.9 1.0 1 0 0 1 1 1 0 Putative transmembrane protein RP-C_C PF11800.3 KOS17792.1 - 0.052 13.2 16.0 0.066 12.9 11.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Spore_coat_CotO PF14153.1 KOS17792.1 - 0.055 12.9 32.5 0.061 12.7 22.5 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DUF2852 PF11014.3 KOS17792.1 - 0.063 13.2 8.1 0.091 12.7 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Neur_chan_memb PF02932.11 KOS17792.1 - 0.074 12.9 16.8 0.086 12.7 11.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Neur PF00064.13 KOS17792.1 - 0.092 10.8 3.7 0.11 10.5 2.6 1.0 1 0 0 1 1 1 0 Neuraminidase FLO_LFY PF01698.11 KOS17792.1 - 0.095 11.5 24.4 0.15 10.8 16.9 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein ABC2_membrane_2 PF12679.2 KOS17792.1 - 0.11 11.3 0.4 0.13 11.0 0.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein CLN3 PF02487.12 KOS17792.1 - 0.15 10.7 3.6 0.18 10.5 2.5 1.2 1 0 0 1 1 1 0 CLN3 protein 7tm_7 PF08395.7 KOS17792.1 - 0.16 10.9 1.3 0.18 10.7 0.9 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor SAPS PF04499.10 KOS17792.1 - 0.23 10.0 18.1 0.26 9.8 12.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CKAP2_C PF15297.1 KOS17792.1 - 0.24 10.1 27.0 0.28 9.9 18.7 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Hid1 PF12722.2 KOS17792.1 - 0.25 8.9 19.9 0.28 8.7 13.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.7 KOS17792.1 - 0.26 11.2 24.1 0.38 10.6 16.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Nucleoside_tran PF01733.13 KOS17792.1 - 0.26 10.3 8.0 0.32 10.1 5.6 1.2 1 0 0 1 1 1 0 Nucleoside transporter DUF3357 PF11837.3 KOS17792.1 - 0.26 11.1 11.7 43 4.0 8.1 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Ni_hydr_CYTB PF01292.15 KOS17792.1 - 0.29 10.4 1.8 0.39 10.0 1.2 1.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 PTPLA PF04387.9 KOS17792.1 - 0.3 10.5 2.7 0.48 9.8 1.9 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase-like protein, PTPLA RBP_receptor PF14752.1 KOS17792.1 - 0.32 9.2 9.0 0.39 8.9 6.3 1.2 1 0 0 1 1 1 0 Retinol binding protein receptor DUF3449 PF11931.3 KOS17792.1 - 0.39 10.2 22.9 0.47 9.9 15.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) IgaA PF07095.6 KOS17792.1 - 0.39 8.3 5.3 0.47 8.1 3.7 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Tmemb_9 PF05434.6 KOS17792.1 - 0.42 10.3 17.5 0.56 9.9 12.1 1.2 1 0 0 1 1 1 0 TMEM9 Protocadherin PF08374.6 KOS17792.1 - 0.45 10.1 20.4 0.63 9.6 14.1 1.2 1 0 0 1 1 1 0 Protocadherin Sre PF03125.13 KOS17792.1 - 0.45 9.3 4.9 0.54 9.1 3.4 1.2 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor DUF3260 PF11658.3 KOS17792.1 - 0.46 8.5 15.4 0.53 8.3 10.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) RNA_pol_3_Rpc31 PF11705.3 KOS17792.1 - 0.47 10.3 25.3 0.56 10.1 17.5 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2215 PF10225.4 KOS17792.1 - 0.54 9.6 10.5 0.63 9.4 7.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Gastrin PF00918.12 KOS17792.1 - 0.55 11.0 20.7 0.7 10.7 14.3 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Sugar_tr PF00083.19 KOS17792.1 - 0.62 8.5 5.1 0.7 8.3 3.6 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter Otopetrin PF03189.8 KOS17792.1 - 0.66 8.9 8.2 0.89 8.4 5.7 1.2 1 0 0 1 1 1 0 Otopetrin DUF2868 PF11067.3 KOS17792.1 - 0.78 8.8 6.7 0.9 8.6 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF4045 PF13254.1 KOS17792.1 - 0.81 8.9 23.8 0.93 8.7 16.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PIG-P PF08510.7 KOS17792.1 - 0.9 9.1 13.3 7 6.3 9.2 2.0 1 1 0 1 1 1 0 PIG-P DUF3366 PF11846.3 KOS17792.1 - 0.94 9.3 5.3 1.6 8.5 3.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3366) DUF4512 PF14975.1 KOS17792.1 - 0.96 10.3 19.1 1.6 9.5 13.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) CDC45 PF02724.9 KOS17792.1 - 1 7.2 24.0 1.2 7.0 16.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Herpes_env PF01673.13 KOS17792.1 - 1.1 7.7 16.2 1.2 7.5 11.3 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF4569 PF15133.1 KOS17792.1 - 1.1 8.5 17.8 1.3 8.3 12.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Tim54 PF11711.3 KOS17792.1 - 1.1 7.7 18.5 1.7 7.1 12.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3807 PF12720.2 KOS17792.1 - 1.4 9.0 32.8 1.8 8.7 22.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DDHD PF02862.12 KOS17792.1 - 1.5 8.5 22.0 2 8.1 15.2 1.2 1 0 0 1 1 1 0 DDHD domain Shisa PF13908.1 KOS17792.1 - 1.5 8.9 11.9 2.1 8.5 8.2 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Vfa1 PF08432.5 KOS17792.1 - 1.6 8.6 38.2 2.1 8.3 26.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 LicD PF04991.8 KOS17792.1 - 1.8 8.5 11.9 2.3 8.2 8.3 1.2 1 0 0 1 1 1 0 LicD family ExbD PF02472.11 KOS17792.1 - 1.9 8.5 13.7 2.4 8.1 9.5 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR m04gp34like PF12216.3 KOS17792.1 - 2 7.7 6.4 2.6 7.2 4.5 1.2 1 0 0 1 1 1 0 Immune evasion protein DUF3450 PF11932.3 KOS17792.1 - 2.2 7.4 28.1 2.8 7.1 19.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cytochrom_B_N PF00033.14 KOS17792.1 - 2.6 7.3 8.0 8.7 5.6 5.5 1.8 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB BORG_CEP PF14957.1 KOS17792.1 - 2.7 8.9 17.4 3.3 8.6 12.1 1.1 1 0 0 1 1 1 0 Cdc42 effector DUF2413 PF10310.4 KOS17792.1 - 2.8 6.6 32.4 3.2 6.4 22.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) AUX_IAA PF02309.11 KOS17792.1 - 2.8 7.6 23.7 3.4 7.3 16.4 1.1 1 0 0 1 1 1 0 AUX/IAA family Band_3_cyto PF07565.8 KOS17792.1 - 3 7.2 23.3 4.1 6.8 16.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF1168 PF06658.7 KOS17792.1 - 3.1 7.3 43.4 4.9 6.6 30.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF1632 PF07857.7 KOS17792.1 - 3.6 6.7 4.8 4.8 6.3 3.4 1.3 1 0 0 1 1 1 0 CEO family (DUF1632) MAPEG PF01124.13 KOS17792.1 - 4.1 7.0 6.4 14 5.2 4.4 1.8 1 1 0 1 1 1 0 MAPEG family Endonuc_Holl PF10107.4 KOS17792.1 - 4.3 7.0 23.8 5.9 6.5 16.5 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase YABBY PF04690.8 KOS17792.1 - 4.5 7.4 18.5 5.5 7.2 12.8 1.0 1 0 0 1 1 1 0 YABBY protein Raftlin PF15250.1 KOS17792.1 - 5.1 5.4 22.1 6.5 5.1 15.3 1.1 1 0 0 1 1 1 0 Raftlin PPP4R2 PF09184.6 KOS17792.1 - 5.3 6.4 22.9 6.6 6.1 15.9 1.1 1 0 0 1 1 1 0 PPP4R2 Plasmodium_Vir PF05795.6 KOS17792.1 - 5.4 6.1 18.6 7.3 5.6 12.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM60A PF15396.1 KOS17792.1 - 5.5 6.6 26.6 7 6.3 18.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A BatD PF13584.1 KOS17792.1 - 6 5.3 22.9 0.028 13.0 7.1 2.0 1 1 1 2 2 1 0 Oxygen tolerance NPR3 PF03666.8 KOS17792.1 - 6.4 5.1 28.9 8 4.8 20.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Herpes_DNAp_acc PF04929.7 KOS17792.1 - 6.7 5.5 20.7 8.4 5.2 14.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Rtf2 PF04641.7 KOS17792.1 - 6.7 5.8 37.1 8.1 5.5 25.7 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2201_N PF13203.1 KOS17792.1 - 7.4 5.6 25.7 9 5.3 17.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain FAM91_C PF14648.1 KOS17792.1 - 7.4 5.2 14.8 8.7 5.0 10.2 1.0 1 0 0 1 1 1 0 FAM91 C-terminus CDK5_activator PF03261.10 KOS17792.1 - 8 5.6 17.9 9.9 5.3 12.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Conotoxin PF02950.12 KOS17792.1 - 8.5 7.2 27.1 8e+03 -2.3 18.8 2.4 1 1 0 1 1 0 0 Conotoxin Adaptin_binding PF10199.4 KOS17792.1 - 8.5 6.6 27.9 13 6.0 19.3 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CPSF100_C PF13299.1 KOS17792.1 - 8.6 6.5 20.9 13 5.8 14.5 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SelP_N PF04592.9 KOS17792.1 - 8.9 5.6 21.0 11 5.2 14.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MIP-T3 PF10243.4 KOS17792.1 - 8.9 4.6 50.3 11 4.4 34.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NARP1 PF12569.3 KOS17792.1 - 9.5 4.8 37.8 11 4.5 26.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Asp-B-Hydro_N PF05279.6 KOS17792.1 - 9.5 5.9 23.9 12 5.7 16.6 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF897 PF05982.7 KOS17792.1 - 10 4.8 10.6 21 3.8 7.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF897) Fungal_trans PF04082.13 KOS17793.1 - 2.1e-31 108.7 0.0 3.3e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DnaJ PF00226.26 KOS17794.1 - 3.7e-25 87.4 0.6 3.7e-25 87.4 0.4 2.0 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 KOS17794.1 - 6.7e-10 38.8 1.0 1.5e-09 37.6 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS17794.1 - 6e-09 35.8 2.4 1.4e-08 34.5 1.7 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KOS17794.1 - 6.9e-05 22.9 1.1 0.00015 21.7 0.8 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KOS17794.1 - 0.00038 20.6 0.7 0.0011 19.1 0.5 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KOS17794.1 - 0.018 14.9 0.4 0.039 13.8 0.3 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KOS17794.1 - 0.023 15.0 0.3 0.081 13.2 0.2 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger RPT PF13446.1 KOS17794.1 - 0.043 13.2 0.0 0.18 11.2 0.0 2.0 1 1 0 1 1 1 0 A repeated domain in UCH-protein DUF3527 PF12043.3 KOS17794.1 - 0.06 12.8 2.0 0.076 12.5 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) DUF2387 PF09526.5 KOS17794.1 - 0.13 12.2 1.5 0.36 10.7 1.1 1.7 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) G-patch PF01585.18 KOS17795.1 - 1.6e-11 43.7 1.1 2.1e-11 43.3 0.8 1.2 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KOS17795.1 - 0.00058 19.6 0.9 0.00075 19.2 0.6 1.2 1 0 0 1 1 1 1 DExH-box splicing factor binding site Histone PF00125.19 KOS17796.1 - 1.8e-25 88.8 0.0 2.3e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KOS17796.1 - 0.00016 21.6 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Vmethyltransf PF01660.12 KOS17798.1 - 0.15 10.7 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Viral methyltransferase DUF1789 PF08748.6 KOS17799.1 - 2.1 8.4 6.0 1.5 8.9 2.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1789) WD40 PF00400.27 KOS17800.1 - 2e-18 65.5 16.6 4.1e-05 23.3 0.8 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_N PF14781.1 KOS17800.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal MraZ PF02381.13 KOS17800.1 - 0.13 12.0 0.0 28 4.5 0.0 2.6 2 0 0 2 2 2 0 MraZ protein DUF2457 PF10446.4 KOS17800.1 - 0.17 10.5 17.0 0.47 9.1 11.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 KOS17800.1 - 0.68 7.8 8.1 1.2 7.1 5.6 1.3 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 KOS17800.1 - 1.2 8.2 14.4 2.5 7.1 10.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 KOS17800.1 - 1.7 6.4 12.6 2.9 5.7 8.8 1.3 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 KOS17800.1 - 8.9 5.9 19.1 0.1 12.3 7.7 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDK2AP PF09806.4 KOS17801.1 - 0.0061 16.8 4.6 0.0085 16.3 3.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein BAF1_ABF1 PF04684.8 KOS17801.1 - 0.008 15.0 10.6 0.011 14.6 7.3 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor HhH-GPD PF00730.20 KOS17802.1 - 0.00045 20.4 0.0 0.00079 19.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein p450 PF00067.17 KOS17803.1 - 2e-21 76.0 0.0 3e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_72 PF03198.9 KOS17805.1 - 1.1e-125 418.8 4.3 1.4e-125 418.4 3.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KOS17805.1 - 1.2e-19 70.6 3.2 1.2e-19 70.6 2.2 1.8 2 0 0 2 2 2 1 X8 domain Glyco_hydro_2_C PF02836.12 KOS17805.1 - 4.6e-05 22.4 0.1 7.9e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Frag1 PF10277.4 KOS17806.1 - 2e-41 141.8 17.5 2.1e-41 141.7 6.2 2.8 2 0 0 2 2 2 2 Frag1/DRAM/Sfk1 family U3_assoc_6 PF08640.6 KOS17807.1 - 1.9e-24 85.1 1.0 1.2e-23 82.6 0.1 2.5 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 6 TPR_16 PF13432.1 KOS17807.1 - 0.01 16.5 0.3 4.1 8.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat NRDE-2 PF08424.5 KOS17807.1 - 0.017 14.0 0.1 0.051 12.4 0.0 1.8 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 KOS17807.1 - 0.033 13.8 0.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 TPR repeat BAF1_ABF1 PF04684.8 KOS17807.1 - 0.048 12.5 0.5 0.066 12.0 0.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Img2 PF05046.9 KOS17809.1 - 1.3e-14 54.2 0.1 1.6e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) NR_Repeat PF14046.1 KOS17809.1 - 0.045 13.4 0.1 0.069 12.8 0.1 1.2 1 0 0 1 1 1 0 Nuclear receptor repeat DUF1744 PF08490.7 KOS17810.1 - 8.9e-147 488.7 0.0 1.3e-146 488.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KOS17810.1 - 1.5e-62 211.3 0.3 4e-62 209.9 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KOS17810.1 - 3.4e-22 78.8 0.0 2.1e-21 76.2 0.0 2.2 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KOS17810.1 - 1.7e-09 37.5 0.1 4.5e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KOS17810.1 - 1.1e-05 25.3 0.0 3.6e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 RNase_H superfamily CUE PF02845.11 KOS17811.1 - 8.1e-05 22.0 0.0 0.00017 21.0 0.0 1.6 1 0 0 1 1 1 1 CUE domain zf-CCCH PF00642.19 KOS17812.1 - 2.5e-06 27.0 2.9 4.7e-06 26.1 2.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) p450 PF00067.17 KOS17813.1 - 3e-65 220.5 0.0 3.9e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4296 PF14129.1 KOS17813.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) eIF3_N PF09440.5 KOS17814.1 - 4.7e-41 140.0 0.9 9.3e-41 139.1 0.6 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KOS17814.1 - 3.8e-12 46.4 0.0 8.5e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.1 KOS17814.1 - 0.028 15.0 1.4 5.5 7.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ead_Ea22 PF13935.1 KOS17814.1 - 0.065 13.5 0.5 2.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Ead/Ea22-like protein His_Phos_2 PF00328.17 KOS17815.1 - 4.8e-127 424.0 0.2 6.4e-127 423.6 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KOS17815.1 - 1.1e-05 24.9 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 KOS17816.1 - 6.6e-80 267.6 0.0 8.7e-80 267.2 0.0 1.1 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KOS17816.1 - 2.6e-23 80.9 20.6 2.5e-06 27.1 0.1 8.3 9 0 0 9 9 9 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KOS17816.1 - 1.7e-06 26.5 0.0 3.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.3 KOS17816.1 - 1.5e-05 23.4 0.0 1.3 7.0 0.0 3.2 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KOS17816.1 - 0.03 13.0 0.0 1.5 7.4 0.0 2.5 1 1 0 1 1 1 0 Nup133 N terminal like Nol1_Nop2_Fmu PF01189.12 KOS17817.1 - 2.3e-29 102.6 0.0 3e-17 62.9 0.0 3.7 3 0 0 3 3 3 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KOS17817.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KOS17817.1 - 0.22 11.4 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase GTP1_OBG PF01018.17 KOS17818.1 - 2.7e-39 134.3 0.1 1.7e-29 102.4 0.7 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 KOS17818.1 - 3.1e-20 72.2 0.0 5.4e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS17818.1 - 2.7e-06 26.7 0.0 6e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KOS17818.1 - 0.021 14.2 0.0 6.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KOS17818.1 - 0.03 14.5 0.0 0.03 14.5 0.0 2.1 2 0 0 2 2 2 0 ABC transporter ArgK PF03308.11 KOS17818.1 - 0.088 11.5 4.0 0.16 10.7 0.0 2.5 3 0 0 3 3 3 0 ArgK protein Arf PF00025.16 KOS17818.1 - 0.12 11.6 0.0 0.31 10.2 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family Dynamin_N PF00350.18 KOS17818.1 - 0.13 12.0 3.4 1.1 9.0 0.0 2.8 2 1 0 2 2 2 0 Dynamin family DUF3446 PF11928.3 KOS17818.1 - 1.1 9.5 8.3 0.21 11.8 3.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) AAA_23 PF13476.1 KOS17818.1 - 3.1 8.0 9.2 55 4.0 5.3 2.2 2 0 0 2 2 2 0 AAA domain RNA_pol_3_Rpc31 PF11705.3 KOS17818.1 - 9.2 6.1 17.8 17 5.2 12.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DREPP PF05558.7 KOS17819.1 - 0.24 11.2 10.1 0.37 10.6 7.0 1.2 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide RNA_pol_Rpb5_C PF01191.14 KOS17820.1 - 5.6e-36 121.9 0.3 4.8e-35 118.9 0.2 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KOS17820.1 - 3.6e-27 94.5 0.0 5.6e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KOS17820.1 - 0.075 12.8 0.0 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease Histone PF00125.19 KOS17822.1 - 6.8e-10 38.9 0.6 9.3e-10 38.4 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KOS17822.1 - 0.0052 16.8 0.0 0.0085 16.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 KOS17822.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Acetyltransf_1 PF00583.19 KOS17823.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KOS17823.1 - 0.19 11.8 1.4 0.88 9.7 0.1 2.6 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DUF500 PF04366.7 KOS17825.1 - 6.5e-18 64.3 0.0 1.3e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) CDC45 PF02724.9 KOS17825.1 - 0.52 8.2 32.6 0.0041 15.2 8.5 2.3 2 0 0 2 2 2 0 CDC45-like protein DUF1180 PF06679.7 KOS17825.1 - 5.1 6.9 16.6 0.81 9.5 5.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Acetyltransf_1 PF00583.19 KOS17826.1 - 0.00012 21.9 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS17826.1 - 0.098 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pribosyltran PF00156.22 KOS17827.1 - 1.3e-17 63.7 1.6 2e-17 63.0 1.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KOS17827.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Methyltransf_8 PF05148.10 KOS17828.1 - 5.2e-62 209.3 0.2 7.1e-58 195.8 0.0 3.6 2 2 1 3 3 3 3 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KOS17828.1 - 4.6e-06 27.0 0.0 1.6e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KOS17828.1 - 0.17 11.5 0.2 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain CDC45 PF02724.9 KOS17828.1 - 0.4 8.6 5.8 0.6 8.0 4.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Asp_protease PF09668.5 KOS17829.1 - 6.4e-58 193.7 0.1 9e-58 193.2 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KOS17829.1 - 1.5e-12 47.8 0.1 5.6e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 KOS17829.1 - 2.7e-08 33.4 0.2 7.6e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KOS17829.1 - 1.1e-06 28.6 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease ubiquitin PF00240.18 KOS17829.1 - 2.7e-06 26.6 0.0 6.2e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family RVP PF00077.15 KOS17829.1 - 3.6e-05 23.6 0.0 0.00017 21.4 0.0 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease UN_NPL4 PF11543.3 KOS17829.1 - 0.018 15.3 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Ubiquitin_2 PF14560.1 KOS17829.1 - 0.13 12.5 0.1 0.33 11.2 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain DUF925 PF06042.6 KOS17829.1 - 0.15 11.5 0.2 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF925) Acyl-CoA_ox_N PF14749.1 KOS17829.1 - 0.25 11.6 2.5 0.43 10.8 1.7 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal MRP-L47 PF06984.8 KOS17830.1 - 1.1e-21 76.5 0.2 1.6e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) zf-H2C2_2 PF13465.1 KOS17831.1 - 6.7e-06 26.1 1.9 6.7e-06 26.1 1.3 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KOS17831.1 - 0.00068 19.8 14.9 0.071 13.4 4.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KOS17831.1 - 0.093 13.1 17.4 0.65 10.4 5.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 KOS17831.1 - 0.25 11.5 7.1 0.44 10.7 4.8 1.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 KOS17831.1 - 1 9.1 8.3 2.8 7.7 1.8 2.6 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 KOS17831.1 - 1.6 8.9 6.1 25 5.1 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NOGCT PF08155.6 KOS17832.1 - 2.4e-27 94.3 0.5 4.6e-27 93.4 0.3 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 KOS17832.1 - 6.4e-27 93.2 0.5 1.5e-26 91.9 0.3 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KOS17832.1 - 2.8e-15 56.2 0.0 5.6e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS17832.1 - 8.1e-08 31.6 0.0 1.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KOS17832.1 - 0.00035 21.0 0.1 0.0023 18.4 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 KOS17832.1 - 0.0054 16.5 0.6 3.4 7.4 0.0 2.9 2 1 1 3 3 3 2 Dynamin family DUF2026 PF09641.5 KOS17832.1 - 0.082 12.2 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2026) GDI PF00996.13 KOS17833.1 - 1.2e-174 580.7 0.0 1.5e-174 580.4 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor DUF3047 PF11249.3 KOS17833.1 - 0.021 14.2 0.0 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3047) MoCF_biosynth PF00994.19 KOS17834.1 - 2e-24 85.6 0.0 3.6e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain 5_nucleotid_C PF02872.13 KOS17835.1 - 3.2e-34 118.1 0.0 5.2e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KOS17835.1 - 1.6e-05 24.3 0.2 0.0027 17.1 0.1 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Adaptin_binding PF10199.4 KOS17836.1 - 3.9 7.7 21.2 18 5.5 12.3 3.2 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Xpo1 PF08389.7 KOS17837.1 - 8.7e-27 93.8 3.1 3.5e-26 91.8 0.0 3.5 5 0 0 5 5 5 1 Exportin 1-like protein Adaptin_N PF01602.15 KOS17837.1 - 0.045 12.0 0.9 3.9 5.6 0.0 3.0 2 1 0 3 3 3 0 Adaptin N terminal region Ras PF00071.17 KOS17838.1 - 1.5e-43 147.9 0.3 1.9e-43 147.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS17838.1 - 6.3e-12 46.0 0.0 1.1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KOS17838.1 - 2.1e-06 27.2 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KOS17838.1 - 0.00029 20.1 0.1 0.00036 19.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family VGCC_beta4Aa_N PF12052.3 KOS17838.1 - 0.62 9.9 2.1 0.64 9.9 0.1 2.0 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal GATA PF00320.22 KOS17839.1 - 1.2 8.5 8.7 12 5.3 0.1 3.4 3 0 0 3 3 3 0 GATA zinc finger zf-B_box PF00643.19 KOS17839.1 - 2.9 7.8 7.7 11 6.0 0.8 3.5 3 0 0 3 3 3 0 B-box zinc finger RIO1 PF01163.17 KOS17840.1 - 8.6e-41 139.3 0.1 5e-40 136.8 0.1 1.9 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 KOS17840.1 - 3.9e-22 78.1 0.0 7.6e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 KOS17840.1 - 6.4e-09 35.8 0.3 1.8e-05 24.5 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KOS17840.1 - 6e-07 28.7 0.0 1.2e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CobT PF06213.7 KOS17840.1 - 0.00077 18.6 12.2 0.0011 18.1 8.5 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Prothymosin PF03247.9 KOS17840.1 - 0.037 14.1 18.5 0.07 13.2 12.8 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Sigma70_ner PF04546.8 KOS17840.1 - 0.038 13.5 11.3 0.064 12.8 7.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 KOS17840.1 - 0.17 10.6 21.7 0.23 10.1 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 KOS17840.1 - 0.34 11.1 14.8 0.67 10.2 10.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RNA_pol_3_Rpc31 PF11705.3 KOS17840.1 - 0.45 10.4 18.5 0.8 9.6 12.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Bd3614_N PF14442.1 KOS17840.1 - 0.63 10.0 5.7 1.2 9.0 4.0 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Myc_N PF01056.13 KOS17840.1 - 0.74 8.9 7.2 1.2 8.2 5.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Vfa1 PF08432.5 KOS17840.1 - 0.78 9.7 6.3 1.4 8.8 4.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3245 PF11595.3 KOS17840.1 - 0.82 9.9 10.4 1.6 8.9 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) PBP1_TM PF14812.1 KOS17840.1 - 0.88 9.9 11.3 1.9 8.8 7.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 KOS17840.1 - 0.92 9.2 7.9 1.9 8.2 5.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2890 PF11081.3 KOS17840.1 - 1.4 8.9 8.5 2.3 8.2 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 KOS17840.1 - 2 6.2 17.8 2.6 5.8 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KOS17840.1 - 2.2 6.6 13.3 2.8 6.2 9.2 1.1 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 KOS17840.1 - 3.4 7.1 16.2 6.3 6.2 11.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 KOS17840.1 - 4.3 6.4 14.0 6.3 5.9 9.7 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 KOS17840.1 - 4.6 5.1 10.7 6.1 4.7 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.17 KOS17841.1 - 1.6e-23 82.0 0.0 1.1e-11 44.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS17841.1 - 3.7e-15 55.6 0.0 4.7e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS17841.1 - 0.00032 20.4 0.1 0.6 10.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 5-FTHF_cyc-lig PF01812.15 KOS17842.1 - 8.9e-33 113.6 0.0 1e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family PC_rep PF01851.17 KOS17843.1 - 2.7e-20 71.3 15.7 2.4e-06 27.4 0.2 8.5 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KOS17843.1 - 2e-08 34.4 0.3 0.038 14.2 0.0 4.0 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 KOS17843.1 - 0.034 14.2 0.0 23 5.4 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat ResIII PF04851.10 KOS17844.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KOS17844.1 - 0.02 14.4 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KOS17844.1 - 0.031 13.8 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF4224 PF13986.1 KOS17844.1 - 0.077 12.5 0.4 2.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) AAA_5 PF07728.9 KOS17845.1 - 2.6e-129 425.7 0.0 3.6e-22 78.5 0.0 9.5 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KOS17845.1 - 7.2e-32 109.7 0.0 4.4e-09 36.0 0.0 7.5 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KOS17845.1 - 1.4e-29 102.9 0.0 0.00036 20.7 0.0 7.2 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KOS17845.1 - 8.7e-26 91.0 9.3 6.8e-05 22.9 0.9 7.1 6 1 0 6 6 6 4 AAA ATPase domain AAA_17 PF13207.1 KOS17845.1 - 3.9e-22 79.3 0.0 0.022 15.5 0.0 6.9 6 1 0 6 6 6 4 AAA domain AAA_22 PF13401.1 KOS17845.1 - 4.6e-22 78.5 0.2 0.0059 16.7 0.0 8.0 8 0 0 8 8 6 4 AAA domain Sigma54_activ_2 PF14532.1 KOS17845.1 - 1.9e-21 76.5 0.3 5.3e-05 23.2 0.1 7.3 8 0 0 8 8 5 2 Sigma-54 interaction domain AAA_14 PF13173.1 KOS17845.1 - 7.5e-20 71.1 0.0 0.00037 20.4 0.0 7.2 7 1 0 7 7 6 4 AAA domain AAA_33 PF13671.1 KOS17845.1 - 1.7e-19 70.0 0.0 0.0033 17.3 0.0 7.2 6 1 0 6 6 6 4 AAA domain Sigma54_activat PF00158.21 KOS17845.1 - 2e-19 69.6 0.0 0.0041 16.6 0.0 6.1 6 0 0 6 6 5 4 Sigma-54 interaction domain AAA_18 PF13238.1 KOS17845.1 - 9e-18 64.8 0.0 0.033 14.5 0.0 6.4 7 0 0 7 7 5 4 AAA domain UPF0079 PF02367.12 KOS17845.1 - 4e-15 55.5 3.2 0.014 15.0 0.2 5.3 5 0 0 5 5 5 3 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KOS17845.1 - 9.2e-15 54.1 2.9 0.022 13.9 0.1 6.0 6 0 0 6 6 6 3 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KOS17845.1 - 6.5e-14 51.9 0.7 0.087 13.0 0.0 6.4 6 0 0 6 6 6 3 RNA helicase T2SE PF00437.15 KOS17845.1 - 7.3e-14 51.3 1.6 0.0089 14.9 0.0 5.2 5 0 0 5 5 5 3 Type II/IV secretion system protein Zeta_toxin PF06414.7 KOS17845.1 - 7.9e-14 51.2 2.9 0.12 11.4 0.0 6.2 6 0 0 6 6 5 3 Zeta toxin NACHT PF05729.7 KOS17845.1 - 1.2e-13 51.0 1.5 0.042 13.4 0.1 5.7 6 0 0 6 6 5 3 NACHT domain ABC_tran PF00005.22 KOS17845.1 - 1.2e-13 51.5 2.4 0.0012 19.1 0.0 7.0 6 1 0 6 6 6 2 ABC transporter RuvB_N PF05496.7 KOS17845.1 - 3.3e-13 49.2 0.9 0.051 12.6 0.0 6.3 6 0 0 6 6 6 3 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KOS17845.1 - 5.8e-13 48.3 6.7 0.037 13.7 0.0 6.7 6 0 0 6 6 6 2 Part of AAA domain Miro PF08477.8 KOS17845.1 - 3.4e-12 46.8 0.6 1.6 9.2 0.0 5.8 5 0 0 5 5 5 1 Miro-like protein AAA_30 PF13604.1 KOS17845.1 - 3.5e-12 46.3 0.4 0.0093 15.5 0.0 7.1 7 1 0 7 7 6 1 AAA domain IstB_IS21 PF01695.12 KOS17845.1 - 4.1e-11 42.6 0.1 0.09 12.1 0.0 5.9 6 0 0 6 6 6 2 IstB-like ATP binding protein AAA_28 PF13521.1 KOS17845.1 - 5.8e-11 42.6 0.5 3.4 7.6 0.0 6.2 6 0 0 6 6 5 0 AAA domain Mg_chelatase PF01078.16 KOS17845.1 - 5.9e-11 41.9 1.3 3.2 6.8 0.0 8.1 8 0 0 8 8 7 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KOS17845.1 - 2.4e-10 40.1 1.1 0.089 12.1 0.0 5.5 7 0 0 7 7 4 2 AAA domain Arch_ATPase PF01637.13 KOS17845.1 - 4.5e-10 39.6 0.0 0.74 9.4 0.0 5.8 6 0 0 6 6 5 1 Archaeal ATPase MobB PF03205.9 KOS17845.1 - 1.9e-09 37.3 0.5 0.31 10.7 0.0 5.3 6 0 0 6 6 5 2 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 KOS17845.1 - 3e-09 36.1 1.1 0.23 10.3 0.0 5.1 5 0 0 5 5 5 3 Protein of unknown function (DUF815) NTPase_1 PF03266.10 KOS17845.1 - 3.1e-08 33.4 5.1 0.29 10.8 0.0 5.2 5 0 0 5 5 4 2 NTPase AAA_29 PF13555.1 KOS17845.1 - 3.5e-08 32.8 0.0 2.2 7.8 0.0 5.8 6 0 0 6 6 5 0 P-loop containing region of AAA domain Dynein_heavy PF03028.10 KOS17845.1 - 1e-07 30.4 0.0 0.06 11.3 0.0 5.9 6 2 0 6 6 6 1 Dynein heavy chain and region D6 of dynein motor AAA_2 PF07724.9 KOS17845.1 - 1.4e-07 31.6 0.0 2.4 8.0 0.0 5.9 5 0 0 5 5 5 0 AAA domain (Cdc48 subfamily) PduV-EutP PF10662.4 KOS17845.1 - 2.4e-07 30.3 2.6 0.098 12.1 0.0 4.9 5 0 0 5 5 5 2 Ethanolamine utilisation - propanediol utilisation TIP49 PF06068.8 KOS17845.1 - 2.5e-07 29.7 0.6 0.17 10.5 0.0 5.1 6 0 0 6 6 6 1 TIP49 C-terminus SRP54 PF00448.17 KOS17845.1 - 4.5e-07 29.5 4.4 0.31 10.4 0.0 5.1 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain AAA_11 PF13086.1 KOS17845.1 - 4.6e-07 29.6 0.0 1.1 8.8 0.0 5.4 6 0 0 6 6 5 1 AAA domain AAA_23 PF13476.1 KOS17845.1 - 7.2e-07 29.7 0.0 2.8 8.2 0.0 4.8 4 0 0 4 4 4 0 AAA domain MMR_HSR1 PF01926.18 KOS17845.1 - 3.9e-06 26.8 0.3 20 5.1 0.0 5.4 5 0 0 5 5 5 0 50S ribosome-binding GTPase Rad17 PF03215.10 KOS17845.1 - 5e-06 25.4 0.4 0.37 9.4 0.0 4.4 5 0 0 5 5 5 2 Rad17 cell cycle checkpoint protein Bac_DnaA PF00308.13 KOS17845.1 - 1e-05 25.3 0.5 9.3 5.8 0.0 4.9 5 0 0 5 5 4 0 Bacterial dnaA protein AAA_24 PF13479.1 KOS17845.1 - 1e-05 25.2 0.2 11 5.5 0.0 5.9 6 0 0 6 6 6 0 AAA domain ResIII PF04851.10 KOS17845.1 - 1e-05 25.4 0.1 1.8 8.3 0.0 4.9 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit NB-ARC PF00931.17 KOS17845.1 - 1.1e-05 24.4 1.3 0.79 8.5 0.0 4.2 4 0 0 4 4 4 1 NB-ARC domain AAA_7 PF12775.2 KOS17845.1 - 1.4e-05 24.3 3.5 1 8.3 0.0 4.8 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 Viral_helicase1 PF01443.13 KOS17845.1 - 2.4e-05 23.9 0.1 7.1 6.0 0.0 5.2 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 KOS17845.1 - 4.5e-05 22.9 4.6 7.2 6.0 0.0 5.7 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 KOS17845.1 - 0.00015 20.8 0.0 2 7.3 0.0 4.8 5 0 0 5 5 5 0 KAP family P-loop domain SRPRB PF09439.5 KOS17845.1 - 0.00017 20.8 0.8 5.1 6.2 0.0 5.0 5 0 0 5 5 5 0 Signal recognition particle receptor beta subunit PhoH PF02562.11 KOS17845.1 - 0.00019 20.7 0.2 3.6 6.7 0.0 4.4 4 0 0 4 4 4 0 PhoH-like protein DEAD PF00270.24 KOS17845.1 - 0.00028 20.4 0.1 1.8 8.0 0.0 4.2 5 0 0 5 5 3 0 DEAD/DEAH box helicase ATP_bind_1 PF03029.12 KOS17845.1 - 0.00029 20.4 3.3 11 5.4 0.0 4.9 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 KOS17845.1 - 0.00056 19.4 2.4 1.4 8.3 0.0 4.2 5 0 0 5 5 3 1 FtsK/SpoIIIE family CPT PF07931.7 KOS17845.1 - 0.0014 18.3 1.8 14 5.2 0.0 5.7 7 1 0 7 7 4 0 Chloramphenicol phosphotransferase-like protein Thymidylate_kin PF02223.12 KOS17845.1 - 0.0016 17.8 7.5 4.7 6.5 0.0 6.2 7 1 1 8 8 5 0 Thymidylate kinase DUF853 PF05872.7 KOS17845.1 - 0.0017 16.8 0.4 0.45 8.7 0.1 2.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) MCM PF00493.18 KOS17845.1 - 0.002 16.9 0.1 19 3.9 0.0 5.2 7 0 0 7 7 5 0 MCM2/3/5 family KTI12 PF08433.5 KOS17845.1 - 0.0021 17.3 0.1 4.2 6.4 0.0 4.3 4 0 0 4 4 4 0 Chromatin associated protein KTI12 ATP-synt_ab PF00006.20 KOS17845.1 - 0.0026 17.2 0.0 10 5.5 0.0 4.2 4 1 0 5 5 4 0 ATP synthase alpha/beta family, nucleotide-binding domain ArgK PF03308.11 KOS17845.1 - 0.0027 16.5 2.4 1.8 7.3 0.0 4.2 4 0 0 4 4 4 0 ArgK protein SKI PF01202.17 KOS17845.1 - 0.003 17.4 0.4 28 4.5 0.0 4.7 5 0 0 5 5 4 0 Shikimate kinase TrwB_AAD_bind PF10412.4 KOS17845.1 - 0.0036 15.9 1.6 22 3.5 0.0 4.7 5 0 0 5 5 5 0 Type IV secretion-system coupling protein DNA-binding domain Septin PF00735.13 KOS17845.1 - 0.0051 15.8 1.3 7.2 5.5 0.0 3.8 5 0 0 5 5 4 0 Septin KaiC PF06745.8 KOS17845.1 - 0.0086 15.2 0.1 7.6 5.5 0.0 3.8 4 0 0 4 4 4 0 KaiC Phe_ZIP PF08916.6 KOS17845.1 - 0.011 16.0 0.7 8.4 6.7 0.0 3.8 4 0 0 4 4 2 0 Phenylalanine zipper DnaB_C PF03796.10 KOS17845.1 - 0.012 14.4 0.2 0.61 8.9 0.0 2.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain IPT PF01745.11 KOS17845.1 - 0.016 14.3 0.2 6.6 5.8 0.0 3.7 4 0 0 4 4 4 0 Isopentenyl transferase DAP3 PF10236.4 KOS17845.1 - 0.018 13.9 5.0 4.3 6.1 0.0 4.8 6 0 0 6 6 5 0 Mitochondrial ribosomal death-associated protein 3 Y_phosphatase PF00102.22 KOS17845.1 - 0.024 13.9 0.0 2.2 7.5 0.0 3.4 4 0 0 4 4 3 0 Protein-tyrosine phosphatase AAA_10 PF12846.2 KOS17845.1 - 0.029 13.8 0.1 64 2.8 0.0 4.8 4 0 0 4 4 4 0 AAA-like domain PIF1 PF05970.9 KOS17845.1 - 0.031 13.2 0.5 82 1.9 0.0 5.6 8 0 0 8 8 7 0 PIF1-like helicase Ras PF00071.17 KOS17845.1 - 0.051 12.9 1.7 41 3.5 0.0 4.3 5 0 0 5 5 4 0 Ras family APS_kinase PF01583.15 KOS17845.1 - 0.069 12.7 0.2 99 2.5 0.0 4.4 5 0 0 5 5 4 0 Adenylylsulphate kinase PRK PF00485.13 KOS17845.1 - 0.09 12.3 0.0 12 5.4 0.0 3.3 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.1 KOS17845.1 - 0.1 11.6 0.0 6.1 5.7 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain VirE PF05272.6 KOS17845.1 - 0.12 11.8 0.0 51 3.2 0.0 3.9 4 0 0 4 4 4 0 Virulence-associated protein E DUF87 PF01935.12 KOS17845.1 - 0.12 12.1 6.3 8.2 6.1 0.0 4.0 3 1 0 3 3 2 0 Domain of unknown function DUF87 Hpr_kinase_C PF07475.7 KOS17845.1 - 0.13 11.5 3.6 0.85 8.9 0.1 3.5 4 0 0 4 4 4 0 HPr Serine kinase C-terminal domain DNA_pol3_delta2 PF13177.1 KOS17845.1 - 0.15 11.6 0.0 6.4 6.4 0.0 3.3 4 0 0 4 4 3 0 DNA polymerase III, delta subunit G-alpha PF00503.15 KOS17845.1 - 0.18 10.4 0.1 10 4.7 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.13 KOS17845.1 - 0.18 11.0 1.6 62 2.8 0.0 4.2 5 0 0 5 5 4 0 Ferrous iron transport protein B Peptidase_S41 PF03572.13 KOS17845.1 - 0.19 11.1 0.1 23 4.3 0.0 2.5 2 0 0 2 2 2 0 Peptidase family S41 Dynamin_N PF00350.18 KOS17845.1 - 0.28 10.9 1.1 7.8 6.2 0.0 3.2 3 0 0 3 3 3 0 Dynamin family DBI_PRT PF02277.12 KOS17845.1 - 0.3 10.1 0.1 23 3.9 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosyltransferase CbiA PF01656.18 KOS17845.1 - 0.98 8.7 2.8 27 4.0 0.0 4.0 6 0 0 6 6 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ribosomal_L12 PF00542.14 KOS17846.1 - 1.6e-18 66.4 7.0 8.4e-18 64.1 2.9 2.3 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain CTK3 PF12243.3 KOS17847.1 - 3.8e-55 185.3 0.3 5.1e-55 184.9 0.2 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KOS17847.1 - 2.1e-19 69.3 8.2 5.1e-19 68.0 5.7 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Lipase_GDSL_2 PF13472.1 KOS17848.1 - 3.4e-10 40.3 0.0 4.5e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KOS17848.1 - 2.7e-08 33.9 0.0 3.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Isochorismatase PF00857.15 KOS17850.1 - 8.1e-19 68.2 0.0 2.7e-18 66.4 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family Hat1_N PF10394.4 KOS17852.1 - 9.5e-27 94.0 0.0 1.5e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus LMBR1 PF04791.11 KOS17853.1 - 8e-21 74.1 10.8 1e-19 70.5 7.5 2.0 1 1 0 1 1 1 1 LMBR1-like membrane protein Mpv17_PMP22 PF04117.7 KOS17854.1 - 4.2e-17 61.5 0.1 4.2e-17 61.5 0.0 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family p450 PF00067.17 KOS17855.1 - 1.9e-46 158.5 0.0 9.6e-28 96.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF802 PF05650.6 KOS17855.1 - 0.18 11.9 1.5 0.4 10.8 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF802) Ank_2 PF12796.2 KOS17856.1 - 4e-14 52.7 0.1 1.7e-06 28.2 0.0 3.5 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KOS17856.1 - 1.4e-11 43.5 2.0 0.0048 16.6 0.1 5.4 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KOS17856.1 - 2e-09 36.7 0.4 0.21 11.9 0.0 5.1 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KOS17856.1 - 5.1e-09 36.0 1.5 0.0024 18.0 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KOS17856.1 - 4.7e-08 33.3 0.5 0.00017 21.9 0.0 4.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) F-box PF00646.28 KOS17856.1 - 0.0025 17.4 0.2 0.0051 16.4 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KOS17856.1 - 0.023 14.4 0.1 0.046 13.4 0.1 1.5 1 0 0 1 1 1 0 F-box-like PRANC PF09372.5 KOS17856.1 - 0.049 13.6 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 PRANC domain DUF1376 PF07120.6 KOS17856.1 - 0.13 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) JAB PF01398.16 KOS17857.1 - 2.8e-34 117.2 0.0 4.9e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KOS17857.1 - 2.6e-26 91.9 1.3 2.6e-26 91.9 0.9 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KOS17857.1 - 2.6e-08 33.3 0.0 4.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RNA_pol_Rpc34 PF05158.7 KOS17858.1 - 1.8e-97 326.4 0.0 2.6e-97 325.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 KOS17858.1 - 2.1e-05 24.8 0.8 0.0048 17.2 0.0 3.3 4 0 0 4 4 4 1 Replication protein A C terminal B-block_TFIIIC PF04182.7 KOS17858.1 - 0.0017 18.1 0.0 0.0043 16.8 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC Ribosomal_S25 PF03297.10 KOS17858.1 - 0.0055 16.7 0.1 0.015 15.3 0.1 1.7 1 0 0 1 1 1 1 S25 ribosomal protein HTH_36 PF13730.1 KOS17858.1 - 0.013 15.6 0.0 0.076 13.1 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.17 KOS17858.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 MarR family Pro_isomerase PF00160.16 KOS17859.1 - 5.2e-44 150.1 0.3 5.9e-44 150.0 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.15 KOS17860.1 - 3e-47 159.5 0.2 4.4e-47 159.0 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KOS17860.1 - 0.0007 18.3 0.1 0.001 17.8 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DSS1_SEM1 PF05160.8 KOS17860.1 - 0.031 14.0 1.5 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 DSS1/SEM1 family AAA PF00004.24 KOS17861.1 - 1.2e-50 171.1 0.0 3.2e-42 143.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KOS17861.1 - 4e-07 30.2 0.0 2.5e-05 24.3 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 KOS17861.1 - 4.2e-07 29.5 0.0 2.4e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 KOS17861.1 - 1.1e-05 25.3 0.0 3.1e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KOS17861.1 - 6.3e-05 23.1 0.0 0.002 18.2 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KOS17861.1 - 0.00025 20.9 0.3 0.0098 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KOS17861.1 - 0.00041 20.0 0.0 0.0017 18.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 KOS17861.1 - 0.0011 19.0 0.0 0.063 13.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 KOS17861.1 - 0.0018 18.1 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KOS17861.1 - 0.0018 18.5 0.2 0.043 14.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KOS17861.1 - 0.0024 18.0 0.0 0.0078 16.3 0.0 1.9 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 KOS17861.1 - 0.0028 17.9 0.0 0.17 12.2 0.0 3.1 2 1 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 KOS17861.1 - 0.0031 18.3 0.4 0.022 15.5 0.0 2.8 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 KOS17861.1 - 0.0063 15.2 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KOS17861.1 - 0.015 14.3 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KOS17861.1 - 0.032 13.9 0.0 0.032 13.9 0.0 2.5 3 0 0 3 3 1 0 Part of AAA domain Mg_chelatase PF01078.16 KOS17861.1 - 0.042 13.0 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KOS17861.1 - 0.048 13.3 0.1 0.2 11.3 0.0 2.1 2 1 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 KOS17861.1 - 0.058 12.8 0.0 2 7.8 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_3 PF07726.6 KOS17861.1 - 0.07 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 KOS17861.1 - 0.071 11.9 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Bromodomain PF00439.20 KOS17861.1 - 0.084 12.8 0.1 0.31 10.9 0.0 1.9 1 0 0 1 1 1 0 Bromodomain PhoH PF02562.11 KOS17861.1 - 0.18 11.0 0.1 0.64 9.2 0.0 1.8 1 1 0 1 1 1 0 PhoH-like protein Torsin PF06309.6 KOS17861.1 - 0.32 10.8 0.0 0.76 9.6 0.0 1.5 1 0 0 1 1 1 0 Torsin DUF663 PF04950.7 KOS17863.1 - 2.9e-88 295.6 0.0 2.9e-88 295.6 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KOS17863.1 - 4e-25 87.1 0.0 1.6e-24 85.2 0.0 2.1 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KOS17863.1 - 1.8e-05 24.2 0.0 0.0038 16.6 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KOS17863.1 - 2.4e-05 24.4 0.0 0.00011 22.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KOS17863.1 - 5.7e-05 23.2 0.0 0.00016 21.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KOS17863.1 - 0.00017 21.9 0.1 0.0013 19.0 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 KOS17863.1 - 0.00027 21.4 0.0 0.00092 19.7 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein NACHT PF05729.7 KOS17863.1 - 0.00029 20.5 0.0 0.0006 19.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KOS17863.1 - 0.00067 19.3 0.6 0.0015 18.2 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain MMR_HSR1 PF01926.18 KOS17863.1 - 0.00076 19.4 0.0 0.0022 17.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 KOS17863.1 - 0.00096 19.3 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KOS17863.1 - 0.0013 18.1 0.0 0.0042 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KOS17863.1 - 0.0018 17.9 0.1 0.0063 16.2 0.1 1.9 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KOS17863.1 - 0.0026 17.2 0.1 0.01 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 KOS17863.1 - 0.0033 17.2 0.6 0.011 15.6 0.0 2.2 2 0 0 2 2 1 1 AAA domain PduV-EutP PF10662.4 KOS17863.1 - 0.005 16.3 0.0 0.016 14.7 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 KOS17863.1 - 0.0053 17.5 0.0 0.0053 17.5 0.0 5.0 2 1 1 3 3 1 1 AAA domain AAA_14 PF13173.1 KOS17863.1 - 0.0058 16.5 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KOS17863.1 - 0.0096 14.8 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NTPase_1 PF03266.10 KOS17863.1 - 0.011 15.4 0.1 0.022 14.4 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.1 KOS17863.1 - 0.019 14.5 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KOS17863.1 - 0.021 14.2 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KOS17863.1 - 0.021 14.9 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 KOS17863.1 - 0.025 13.7 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KOS17863.1 - 0.057 13.7 0.0 0.057 13.7 0.0 4.8 4 2 1 5 5 3 0 AAA domain AAA_21 PF13304.1 KOS17863.1 - 0.09 12.7 3.2 1 9.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain GRP PF07172.6 KOS17863.1 - 9.2 6.8 16.5 1.9 9.0 3.3 3.2 3 0 0 3 3 2 0 Glycine rich protein family Eaf7 PF07904.8 KOS17865.1 - 1.4e-26 92.2 0.1 1.4e-26 92.2 0.0 1.6 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 Nha1_C PF08619.5 KOS17865.1 - 0.067 12.4 14.1 0.088 12.0 9.8 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus FXR1P_C PF12235.3 KOS17865.1 - 0.31 11.1 25.8 0.51 10.4 17.9 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Nop14 PF04147.7 KOS17865.1 - 1.2 6.9 11.1 1.6 6.5 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KOS17865.1 - 3.1 6.1 10.0 4 5.8 6.9 1.1 1 0 0 1 1 1 0 Daxx Family CDC27 PF09507.5 KOS17865.1 - 4.7 6.3 12.0 5.9 5.9 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NOA36 PF06524.7 KOS17865.1 - 7.6 5.6 9.3 14 4.7 6.4 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2201_N PF13203.1 KOS17865.1 - 8.9 5.3 10.6 11 5.0 7.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Spc97_Spc98 PF04130.8 KOS17866.1 - 1.5e-65 221.5 0.0 2e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF2368 PF10166.4 KOS17866.1 - 0.16 11.5 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) DASH_Ask1 PF08655.5 KOS17867.1 - 4.3e-32 109.7 0.1 7e-32 109.0 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 Cwf_Cwc_15 PF04889.7 KOS17867.1 - 1.7 8.3 14.0 3.8 7.1 9.7 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Defensin_propep PF00879.13 KOS17867.1 - 2.5 8.1 7.4 6.3 6.8 0.3 2.8 2 0 0 2 2 2 0 Defensin propeptide TACC PF05010.9 KOS17868.1 - 0.03 14.0 0.6 0.05 13.3 0.4 1.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Retinal PF15449.1 KOS17869.1 - 0.089 10.4 3.1 0.097 10.3 2.1 1.2 1 0 0 1 1 1 0 Retinal protein KH_1 PF00013.24 KOS17870.1 - 1.3e-25 88.7 0.7 1.3e-07 31.0 0.2 7.1 8 0 0 8 8 8 5 KH domain KH_3 PF13014.1 KOS17870.1 - 3.4e-24 83.9 2.0 1.9e-05 24.2 0.0 6.0 6 0 0 6 6 6 5 KH domain ResIII PF04851.10 KOS17871.1 - 2.2e-22 79.8 0.0 4.6e-22 78.7 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KOS17871.1 - 5.6e-15 54.9 0.1 2e-14 53.1 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS17871.1 - 1.1e-12 47.8 0.0 1.8e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 KOS17871.1 - 0.0019 17.2 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 KOS17871.1 - 0.036 12.6 0.1 0.069 11.7 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2890 PF11081.3 KOS17872.1 - 0.00085 19.4 15.0 0.00085 19.4 10.4 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF2890) Septin PF00735.13 KOS17873.1 - 4.5e-29 101.3 0.0 2.9e-09 36.3 0.0 3.1 3 0 0 3 3 3 3 Septin G-alpha PF00503.15 KOS17873.1 - 0.012 14.2 0.9 0.015 14.0 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit AAA_23 PF13476.1 KOS17873.1 - 0.019 15.3 0.5 0.045 14.0 0.3 1.7 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 KOS17873.1 - 0.042 14.3 0.0 0.13 12.8 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein FtsK_SpoIIIE PF01580.13 KOS17873.1 - 0.09 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ebola_NP PF05505.7 KOS17873.1 - 0.13 10.2 1.3 0.19 9.7 0.9 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Metallophos PF00149.23 KOS17875.1 - 4e-36 124.2 0.7 1e-28 100.1 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Methyltransf_23 PF13489.1 KOS17876.1 - 4.1e-08 33.0 0.0 0.00017 21.3 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 KOS17876.1 - 1.8e-07 30.8 0.0 1.3e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS17876.1 - 2.4e-06 28.0 0.0 1.3e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS17876.1 - 0.00014 22.3 0.0 0.00081 19.8 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS17876.1 - 0.00023 21.5 0.0 0.0035 17.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS17876.1 - 0.00026 20.4 0.0 0.00062 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KOS17876.1 - 0.00074 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KOS17876.1 - 0.00095 19.1 0.0 0.0024 17.9 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 KOS17876.1 - 0.003 17.8 0.0 0.0061 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS17876.1 - 0.013 15.4 0.0 0.023 14.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KOS17876.1 - 0.038 13.1 0.0 0.15 11.1 0.0 1.9 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KOS17876.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase CDC45 PF02724.9 KOS17877.1 - 6.7e-234 777.5 0.0 6.4e-233 774.3 0.0 2.8 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.7 KOS17877.1 - 0.0083 15.8 10.0 0.0083 15.8 6.9 2.4 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein SMN PF06003.7 KOS17877.1 - 0.47 9.5 7.6 0.053 12.6 0.3 2.3 2 1 0 2 2 2 0 Survival motor neuron protein (SMN) DUF2457 PF10446.4 KOS17877.1 - 1.1 7.9 27.9 0.44 9.2 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TFIIF_alpha PF05793.7 KOS17877.1 - 4.4 5.5 26.8 3.9 5.7 3.2 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDP-OH_P_transf PF01066.16 KOS17878.1 - 1.7e-12 47.5 3.0 1.7e-12 47.5 2.1 3.1 3 2 1 4 4 4 1 CDP-alcohol phosphatidyltransferase JAB PF01398.16 KOS17879.1 - 1.7e-09 37.3 0.4 4.2e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ABC1 PF03109.11 KOS17880.1 - 1.4e-21 76.6 0.0 2.6e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 KOS17880.1 - 3.2e-05 23.7 0.0 9.8e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Orbi_VP2 PF00898.12 KOS17880.1 - 0.093 10.2 0.0 0.13 9.7 0.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 DcpS_C PF11969.3 KOS17882.1 - 5.6e-30 103.9 0.0 1e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KOS17882.1 - 1.8e-17 63.6 0.0 5.4e-17 62.1 0.0 1.8 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DUF2016 PF09436.5 KOS17882.1 - 0.045 13.3 0.2 0.65 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2016) Abhydrolase_4 PF08386.5 KOS17883.1 - 1.4e-14 53.8 0.1 4.8e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 KOS17883.1 - 1e-09 38.3 2.1 2.8e-08 33.6 1.4 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KOS17883.1 - 3e-07 30.5 14.3 3.2e-07 30.4 7.5 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS17883.1 - 0.00012 21.8 0.0 0.00089 19.0 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF4341 PF14241.1 KOS17883.1 - 0.021 14.5 0.1 0.051 13.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4341) SGL PF08450.7 KOS17885.1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.5 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region DUF1275 PF06912.6 KOS17886.1 - 3.7e-36 124.2 17.9 4.8e-36 123.9 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4095 PF13338.1 KOS17887.1 - 0.052 13.6 0.2 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4095) Herpes_capsid PF06112.6 KOS17887.1 - 1.5 8.8 18.6 2.6 8.0 12.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Sporozoite_P67 PF05642.6 KOS17887.1 - 8.2 4.1 11.8 10 3.8 8.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.20 KOS17888.1 - 7.4e-72 241.6 0.0 1.1e-71 241.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17888.1 - 8.9e-36 123.2 0.0 2.7e-35 121.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS17888.1 - 0.00055 18.9 0.2 0.62 8.9 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Orthopox_F8 PF05886.6 KOS17888.1 - 0.038 13.8 2.7 0.14 11.9 1.9 2.0 1 0 0 1 1 1 0 Orthopoxvirus F8 protein APH PF01636.18 KOS17888.1 - 0.22 11.2 8.4 0.3 10.7 1.2 3.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 KOS17889.1 - 1.8e-35 122.3 0.0 2.6e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17889.1 - 6.8e-19 67.9 0.0 3.3e-18 65.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS17889.1 - 5.5e-06 25.5 0.0 9e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS17889.1 - 0.0044 16.7 0.0 0.016 14.9 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KOS17889.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nop25 PF09805.4 KOS17890.1 - 1e-37 129.2 16.9 1e-37 129.2 11.7 1.9 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) YlqD PF11068.3 KOS17890.1 - 0.58 10.1 7.3 1 9.4 5.1 1.3 1 0 0 1 1 1 0 YlqD protein DUF4661 PF15576.1 KOS17890.1 - 1.1 8.8 5.5 0.51 9.9 2.1 1.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4661) Ribosomal_L37 PF08561.5 KOS17890.1 - 8.2 6.0 7.8 20 4.8 5.4 1.8 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L37 ATP-synt_S1 PF05827.7 KOS17892.1 - 4.6e-31 108.1 0.1 1.5e-30 106.5 0.0 1.8 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) bZIP_1 PF00170.16 KOS17893.1 - 1.2e-07 31.6 9.1 2.1e-07 30.7 6.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF737 PF05300.6 KOS17893.1 - 0.011 15.6 0.3 0.011 15.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF737) dsrm PF00035.20 KOS17893.1 - 0.09 13.3 0.7 0.2 12.2 0.5 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif Ribosomal_L30_N PF08079.7 KOS17893.1 - 0.41 10.6 9.7 0.8 9.7 6.7 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Uds1 PF15456.1 KOS17893.1 - 4.2 7.3 9.5 0.39 10.7 3.4 1.6 2 0 0 2 2 2 0 Up-regulated During Septation DUF2786 PF10979.3 KOS17894.1 - 4.1 7.1 7.5 0.6 9.8 2.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) DUF1776 PF08643.5 KOS17895.1 - 0.069 12.2 0.1 0.075 12.1 0.1 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Atrophin-1 PF03154.10 KOS17896.1 - 0.0015 16.8 12.7 0.0015 16.8 8.8 2.1 1 1 1 2 2 2 1 Atrophin-1 family DUF1777 PF08648.7 KOS17896.1 - 6 6.5 32.1 1e+02 2.5 22.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) ABC_tran PF00005.22 KOS17897.1 - 3.8e-46 156.7 0.0 1.7e-21 76.9 0.0 3.3 2 1 1 3 3 3 2 ABC transporter AAA_21 PF13304.1 KOS17897.1 - 1.2e-20 74.6 0.4 0.00013 22.0 0.0 4.2 3 1 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 KOS17897.1 - 4.7e-19 68.0 2.9 4.7e-19 68.0 2.0 2.5 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 KOS17897.1 - 1.1e-10 41.1 0.2 0.0066 15.7 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KOS17897.1 - 1.8e-09 36.9 0.1 0.0009 18.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KOS17897.1 - 3.3e-07 30.5 0.0 0.01 15.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KOS17897.1 - 4.9e-07 30.5 0.1 0.0097 16.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KOS17897.1 - 7.3e-07 29.7 8.3 0.03 14.6 0.1 3.6 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.1 KOS17897.1 - 1.6e-06 28.4 0.1 0.054 13.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KOS17897.1 - 5e-06 25.8 0.0 0.0069 15.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KOS17897.1 - 1.1e-05 25.3 0.0 0.1 12.5 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase NACHT PF05729.7 KOS17897.1 - 1.2e-05 24.9 0.4 0.15 11.6 0.0 2.9 3 0 0 3 3 3 2 NACHT domain Miro PF08477.8 KOS17897.1 - 2.5e-05 24.7 0.0 0.061 13.8 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 KOS17897.1 - 3.2e-05 24.1 0.0 0.26 11.4 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KOS17897.1 - 5.1e-05 23.2 0.1 0.037 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS17897.1 - 6.1e-05 22.9 0.0 0.1 12.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KOS17897.1 - 6.4e-05 23.0 3.1 0.22 11.5 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 KOS17897.1 - 8.6e-05 22.2 0.2 0.37 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KOS17897.1 - 0.00012 21.4 0.0 0.26 10.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 KOS17897.1 - 0.00022 20.7 0.3 0.49 9.7 0.1 2.9 3 1 1 4 4 3 2 AAA-like domain Arch_ATPase PF01637.13 KOS17897.1 - 0.00031 20.4 0.1 0.19 11.4 0.0 2.7 3 0 0 3 3 2 1 Archaeal ATPase AAA_15 PF13175.1 KOS17897.1 - 0.00042 19.4 0.0 0.18 10.7 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_14 PF13173.1 KOS17897.1 - 0.00058 19.7 0.0 1.8 8.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KOS17897.1 - 0.00058 20.0 0.7 1.4 9.1 0.0 2.9 3 0 0 3 3 2 2 RNA helicase MobB PF03205.9 KOS17897.1 - 0.0018 18.0 0.1 0.098 12.3 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KOS17897.1 - 0.0033 17.2 0.5 3.2 7.5 0.0 3.5 4 1 1 5 5 4 1 Dynamin family DUF2813 PF11398.3 KOS17897.1 - 0.0034 16.5 0.6 2.1 7.3 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) NB-ARC PF00931.17 KOS17897.1 - 0.0052 15.6 0.3 0.95 8.2 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain SbcCD_C PF13558.1 KOS17897.1 - 0.0057 16.5 0.4 0.89 9.5 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DAP3 PF10236.4 KOS17897.1 - 0.0066 15.4 0.1 1.3 7.8 0.0 2.7 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 ABC_ATPase PF09818.4 KOS17897.1 - 0.011 14.4 0.8 11 4.4 0.0 3.7 4 0 0 4 4 4 0 Predicted ATPase of the ABC class NTPase_1 PF03266.10 KOS17897.1 - 0.022 14.4 0.5 2.8 7.6 0.2 2.5 2 0 0 2 2 2 0 NTPase DUF815 PF05673.8 KOS17897.1 - 0.028 13.3 0.1 1.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MCM PF00493.18 KOS17897.1 - 0.028 13.2 1.0 5.3 5.7 0.0 2.7 3 0 0 3 3 3 0 MCM2/3/5 family FeoB_N PF02421.13 KOS17897.1 - 0.029 13.6 0.1 7.4 5.8 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B ArgK PF03308.11 KOS17897.1 - 0.031 13.0 0.5 3.8 6.2 0.0 2.6 3 0 0 3 3 3 0 ArgK protein PduV-EutP PF10662.4 KOS17897.1 - 0.065 12.7 0.2 5.8 6.3 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 KOS17897.1 - 0.071 12.9 0.7 18 5.0 0.0 3.0 3 0 0 3 3 2 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 KOS17897.1 - 0.085 12.3 0.0 7.5 5.9 0.0 3.0 3 1 1 4 4 4 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 KOS17897.1 - 0.11 12.0 0.0 6 6.3 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 KOS17897.1 - 0.67 9.4 4.8 10 5.6 0.0 3.8 4 0 0 4 4 4 0 AAA domain RNA_polI_A34 PF08208.6 KOS17899.1 - 1e-30 106.8 2.4 1e-30 106.8 1.6 5.9 3 1 2 5 5 5 1 DNA-directed RNA polymerase I subunit RPA34.5 PAP2 PF01569.16 KOS17900.1 - 8.3e-14 51.3 8.6 8.3e-14 51.3 5.9 2.5 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KOS17900.1 - 1.3e-06 28.0 6.9 1.3e-06 28.0 4.8 2.1 2 1 0 2 2 2 1 PAP2 superfamily SHMT PF00464.14 KOS17901.1 - 2.3e-207 688.1 0.0 2.7e-207 687.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 KOS17901.1 - 2.4e-06 26.5 0.0 3.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KOS17901.1 - 0.0039 16.3 0.0 0.0095 15.1 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Bromodomain PF00439.20 KOS17902.1 - 2.1e-19 69.2 1.6 2.5e-19 68.9 0.2 1.8 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 KOS17902.1 - 6.4e-10 38.6 0.0 1.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated VanZ PF04892.7 KOS17903.1 - 1.2e-12 47.9 1.7 1.5e-12 47.5 1.2 1.1 1 0 0 1 1 1 1 VanZ like family DUF4401 PF14351.1 KOS17903.1 - 0.00035 19.6 0.8 0.00047 19.2 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) Prefoldin PF02996.12 KOS17904.1 - 9.2e-33 112.4 0.1 1.7e-32 111.5 0.1 1.4 1 0 0 1 1 1 1 Prefoldin subunit Filament PF00038.16 KOS17904.1 - 0.063 12.7 5.0 2.3 7.5 0.1 2.0 2 0 0 2 2 2 0 Intermediate filament protein Prefoldin_2 PF01920.15 KOS17904.1 - 0.13 11.9 7.1 0.2 11.4 0.0 3.2 3 1 0 3 3 3 0 Prefoldin subunit Pkinase PF00069.20 KOS17905.1 - 1.5e-69 234.0 0.0 1.8e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17905.1 - 1.8e-29 102.6 0.0 2.4e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS17905.1 - 2.8e-06 26.4 0.0 4.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS17905.1 - 0.00018 21.3 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KOS17905.1 - 0.00029 19.9 0.0 0.00053 19.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KOS17905.1 - 0.02 14.2 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RF-1 PF00472.15 KOS17906.1 - 4.6e-13 48.9 3.0 7.4e-13 48.3 2.1 1.3 1 0 0 1 1 1 1 RF-1 domain bPH_6 PF10756.4 KOS17906.1 - 0.093 12.6 0.2 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial PH domain Glycohydro_20b2 PF14845.1 KOS17906.1 - 0.44 11.1 3.7 0.55 10.8 2.1 1.5 1 1 0 1 1 1 0 beta-acetyl hexosaminidase like RRM_1 PF00076.17 KOS17907.1 - 3.2e-09 36.2 0.0 5.7e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS17907.1 - 8.2e-07 28.9 0.0 2.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS17907.1 - 0.00062 19.5 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ferric_reduct PF01794.14 KOS17908.1 - 3e-16 59.6 15.6 8.1e-16 58.2 10.8 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KOS17908.1 - 3.9e-11 43.0 0.0 2.5e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KOS17908.1 - 0.00033 20.4 0.0 0.0073 16.1 0.0 2.7 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 KOS17908.1 - 0.0082 16.6 0.0 2.3 8.8 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Ras PF00071.17 KOS17909.1 - 8.7e-42 142.2 0.0 3.7e-41 140.2 0.0 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KOS17909.1 - 3.2e-15 56.6 0.0 5.2e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS17909.1 - 4.6e-11 42.2 0.0 4.1e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KOS17909.1 - 5.9e-05 22.3 0.0 8.4e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KOS17909.1 - 0.00016 21.6 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KOS17909.1 - 0.00066 19.1 0.0 0.0028 17.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KOS17909.1 - 0.0011 18.4 0.0 0.16 11.4 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 KOS17909.1 - 0.0022 17.9 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.15 KOS17909.1 - 0.0033 16.1 0.0 0.0091 14.7 0.0 1.6 2 0 0 2 2 2 1 G-protein alpha subunit CENP-B_dimeris PF09026.5 KOS17909.1 - 0.0061 16.7 3.9 0.011 15.9 2.7 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain SRPRB PF09439.5 KOS17909.1 - 0.0064 15.7 0.0 0.0096 15.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KOS17909.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KOS17909.1 - 0.015 15.5 0.2 0.081 13.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.1 KOS17909.1 - 0.031 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KOS17909.1 - 0.042 13.4 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KOS17909.1 - 0.043 13.8 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KOS17909.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KOS17909.1 - 0.059 12.5 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KOS17909.1 - 0.15 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase cobW PF02492.14 KOS17909.1 - 0.16 11.4 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Nucleoplasmin PF03066.10 KOS17909.1 - 2 7.8 5.1 3.3 7.2 3.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin Cwf_Cwc_15 PF04889.7 KOS17909.1 - 2.5 7.7 6.8 3.5 7.2 4.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF229 PF02995.12 KOS17910.1 - 0.095 11.0 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) BCNT PF07572.7 KOS17911.1 - 6.2e-25 86.9 0.8 1.2e-24 85.9 0.6 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development CDC45 PF02724.9 KOS17911.1 - 0.16 10.0 14.2 0.24 9.3 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein His_biosynth PF00977.16 KOS17912.1 - 8.3e-34 116.8 0.0 1e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Anillin PF08174.6 KOS17913.1 - 1.9e-33 115.4 0.1 5.9e-33 113.8 0.1 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KOS17913.1 - 1.9e-09 37.6 0.0 7.2e-09 35.7 0.0 2.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KOS17913.1 - 0.04 14.1 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain DUF1900 PF08954.6 KOS17914.1 - 1.3e-48 163.9 0.0 7.2e-48 161.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KOS17914.1 - 1.6e-35 120.5 0.1 4.5e-35 119.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KOS17914.1 - 1e-26 91.7 0.4 3.6e-08 32.9 0.2 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat AAA_13 PF13166.1 KOS17914.1 - 0.0033 15.9 0.4 0.0045 15.5 0.2 1.1 1 0 0 1 1 1 1 AAA domain Nup160 PF11715.3 KOS17914.1 - 0.01 13.9 0.1 0.59 8.2 0.0 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KOS17914.1 - 0.063 12.0 0.1 0.8 8.3 0.0 2.3 1 1 2 3 3 3 0 Nup133 N terminal like Apc4_WD40 PF12894.2 KOS17914.1 - 0.15 11.6 0.0 22 4.6 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SlyX PF04102.7 KOS17914.1 - 0.52 10.7 4.4 0.4 11.0 0.6 2.3 2 0 0 2 2 2 0 SlyX STE PF02200.11 KOS17915.1 - 7e-62 206.4 0.8 1.4e-61 205.4 0.2 1.7 2 0 0 2 2 2 1 STE like transcription factor Vma12 PF11712.3 KOS17916.1 - 2.8e-20 72.4 0.0 3.8e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2231 PF09990.4 KOS17916.1 - 0.093 13.0 2.6 0.13 12.6 1.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF4602 PF15375.1 KOS17917.1 - 0.00033 20.7 5.1 0.00033 20.7 3.5 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4602) Microvir_J PF04726.8 KOS17917.1 - 0.13 12.2 0.5 0.45 10.5 0.3 2.0 1 0 0 1 1 1 0 Microvirus J protein PBP1_TM PF14812.1 KOS17918.1 - 0.025 14.8 15.5 0.035 14.3 10.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nha1_C PF08619.5 KOS17918.1 - 0.077 12.2 13.8 0.089 12.0 9.6 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus TLP-20 PF06088.6 KOS17918.1 - 0.16 11.6 7.5 0.17 11.5 5.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2457 PF10446.4 KOS17918.1 - 0.23 10.1 18.9 0.24 10.1 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 KOS17918.1 - 0.34 10.5 13.4 0.38 10.3 9.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 KOS17918.1 - 0.64 9.5 12.7 0.75 9.3 8.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 KOS17918.1 - 0.7 9.0 13.7 0.77 8.9 9.5 1.0 1 0 0 1 1 1 0 NOA36 protein Vfa1 PF08432.5 KOS17918.1 - 0.82 9.6 7.5 0.84 9.6 5.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sporozoite_P67 PF05642.6 KOS17918.1 - 0.86 7.3 9.9 0.85 7.3 6.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.6 KOS17918.1 - 1.3 8.8 9.9 1.5 8.6 6.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF1754 PF08555.5 KOS17918.1 - 1.5 9.5 7.3 2.1 8.9 5.1 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) CDC45 PF02724.9 KOS17918.1 - 1.7 6.6 15.7 1.8 6.5 10.9 1.0 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 KOS17918.1 - 1.8 7.3 6.8 2 7.1 4.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein FAM176 PF14851.1 KOS17918.1 - 2.1 7.9 8.0 2.6 7.7 5.5 1.2 1 0 0 1 1 1 0 FAM176 family HSP90 PF00183.13 KOS17918.1 - 2.3 6.5 7.0 2.4 6.4 4.9 1.0 1 0 0 1 1 1 0 Hsp90 protein BTV_NS2 PF04514.7 KOS17918.1 - 3.2 6.5 9.0 3.6 6.3 6.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Tom22 PF04281.8 KOS17918.1 - 3.8 7.0 11.1 4.7 6.7 7.7 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 CobT PF06213.7 KOS17918.1 - 4 6.4 16.8 3.9 6.5 11.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 KOS17918.1 - 4.7 5.5 15.6 5.6 5.3 10.8 1.0 1 0 0 1 1 1 0 Daxx Family DUF2076 PF09849.4 KOS17918.1 - 4.7 7.1 12.7 5.3 7.0 8.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Nop14 PF04147.7 KOS17918.1 - 5 4.9 17.2 5 4.9 12.0 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4611 PF15387.1 KOS17918.1 - 5.1 7.3 16.6 4.7 7.4 10.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) DUF1510 PF07423.6 KOS17918.1 - 5.3 6.3 12.0 5.4 6.3 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 KOS17918.1 - 8.1 5.3 9.5 8.6 5.2 6.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SAPS PF04499.10 KOS17918.1 - 8.6 4.8 7.4 8.2 4.9 5.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CLP_protease PF00574.18 KOS17919.1 - 8.5e-65 217.8 0.2 1.1e-64 217.4 0.2 1.1 1 0 0 1 1 1 1 Clp protease DUF2201_N PF13203.1 KOS17919.1 - 0.12 11.5 2.0 0.15 11.2 1.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain ketoacyl-synt PF00109.21 KOS17920.1 - 4.9e-54 183.4 8.0 4.9e-54 183.4 5.5 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KOS17920.1 - 2.2e-34 117.8 0.9 4.1e-34 116.9 0.6 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KOS17920.1 - 0.00046 19.2 0.2 0.00092 18.2 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KOS17920.1 - 0.044 13.2 0.1 0.044 13.2 0.1 2.8 3 1 1 4 4 4 0 Thiolase, C-terminal domain Apc1 PF12859.2 KOS17921.1 - 3.8e-24 84.9 0.1 1.3e-23 83.1 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KOS17921.1 - 0.00014 21.8 2.4 1.9 8.8 0.1 5.0 5 0 0 5 5 5 2 Proteasome/cyclosome repeat Ubiq_cyt_C_chap PF03981.7 KOS17922.1 - 1.4e-35 122.2 0.6 3.2e-35 121.0 0.0 1.9 3 0 0 3 3 3 1 Ubiquinol-cytochrome C chaperone DUF4040 PF13244.1 KOS17922.1 - 0.065 13.2 0.2 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4040) DHFR_1 PF00186.14 KOS17923.1 - 8e-32 110.0 0.0 1.1e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase zf-HC5HC2H_2 PF13832.1 KOS17924.1 - 1.7e-34 118.1 7.1 1.7e-34 118.1 4.9 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KOS17924.1 - 4.7e-27 93.9 6.1 4.7e-27 93.9 4.2 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 KOS17924.1 - 5.3e-19 69.0 4.6 7e-19 68.6 0.8 2.9 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 KOS17924.1 - 1e-14 53.5 2.4 1e-14 53.5 1.7 2.1 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KOS17924.1 - 5.4e-08 32.4 26.8 7.1e-07 28.8 9.0 2.7 2 0 0 2 2 2 2 PHD-finger COesterase PF00135.23 KOS17925.1 - 6.2e-83 279.3 0.0 1.4e-82 278.1 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KOS17925.1 - 6.4e-07 29.1 0.1 7.3e-06 25.6 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KOS17925.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2360 PF10152.4 KOS17926.1 - 0.61 10.3 5.7 11 6.3 0.1 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Histone PF00125.19 KOS17927.1 - 2.4e-22 78.8 0.2 3.3e-22 78.3 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KOS17927.1 - 4.5e-05 23.4 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KOS17927.1 - 0.00022 21.4 0.0 0.00038 20.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 KOS17927.1 - 0.008 14.8 2.3 0.01 14.5 1.6 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RP-C PF03428.8 KOS17927.1 - 0.017 14.5 0.1 0.024 14.0 0.1 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 KOS17927.1 - 0.019 15.5 0.4 0.026 15.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Myosin_head PF00063.16 KOS17928.1 - 3.7e-200 666.4 3.3 4.2e-200 666.2 2.3 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.1 KOS17928.1 - 6.5e-05 23.0 0.1 0.0004 20.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS17928.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KOS17928.1 - 0.015 15.3 0.0 0.06 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 KOS17928.1 - 0.015 14.7 0.0 0.038 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain T2SE PF00437.15 KOS17928.1 - 0.018 13.9 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 KOS17928.1 - 0.03 13.2 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 KOS17928.1 - 0.045 13.4 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 KOS17928.1 - 0.048 13.1 0.0 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF218 PF02698.12 KOS17928.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 DUF218 domain HSF_DNA-bind PF00447.12 KOS17928.1 - 0.081 13.0 0.4 0.081 13.0 0.3 1.9 2 0 0 2 2 1 0 HSF-type DNA-binding PhoH PF02562.11 KOS17928.1 - 0.1 11.7 0.5 3.2 6.9 0.0 2.8 3 0 0 3 3 3 0 PhoH-like protein NAP PF00956.13 KOS17929.1 - 8.8e-86 286.9 1.1 8.8e-86 286.9 0.8 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Cellulase PF00150.13 KOS17930.1 - 1.3e-10 41.0 1.3 1.3e-07 31.1 0.3 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.20 KOS17931.1 - 5.8e-65 219.0 0.0 8.9e-65 218.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17931.1 - 1.1e-47 162.2 0.0 1.8e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS17931.1 - 1.9e-08 33.6 0.0 4.4e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KOS17931.1 - 0.0031 16.5 0.0 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Vps51 PF08700.6 KOS17932.1 - 1.2e-27 95.5 0.1 2.1e-27 94.7 0.1 1.4 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 KOS17932.1 - 0.00015 20.3 0.1 0.0002 19.9 0.1 1.1 1 0 0 1 1 1 1 Dor1-like family Med4 PF10018.4 KOS17932.1 - 0.043 13.2 0.1 0.073 12.4 0.1 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 COG5 PF10392.4 KOS17932.1 - 0.074 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 NIF3 PF01784.13 KOS17933.1 - 1.2e-54 185.4 0.0 1.5e-54 185.1 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Glycos_transf_3 PF00591.16 KOS17933.1 - 0.081 12.3 0.3 1.7 7.9 0.1 2.2 1 1 1 2 2 2 0 Glycosyl transferase family, a/b domain TPR_11 PF13414.1 KOS17934.1 - 1.3e-36 124.0 58.6 2.1e-06 27.2 0.0 13.5 10 2 1 13 13 13 10 TPR repeat TPR_14 PF13428.1 KOS17934.1 - 7.1e-24 82.1 68.6 0.0046 17.4 0.1 17.3 13 4 5 18 18 16 9 Tetratricopeptide repeat TPR_16 PF13432.1 KOS17934.1 - 6.7e-22 77.5 87.8 2.4e-06 28.0 1.3 15.0 14 3 3 17 17 15 8 Tetratricopeptide repeat TPR_2 PF07719.12 KOS17934.1 - 1.2e-21 74.7 65.3 0.026 14.4 0.0 17.3 17 0 0 17 17 17 10 Tetratricopeptide repeat TPR_17 PF13431.1 KOS17934.1 - 1.6e-17 62.1 23.7 0.031 14.4 0.0 15.2 18 0 0 18 18 18 3 Tetratricopeptide repeat TPR_19 PF14559.1 KOS17934.1 - 1.1e-16 60.9 52.9 0.015 15.6 0.2 13.4 12 2 1 14 14 13 7 Tetratricopeptide repeat TPR_1 PF00515.23 KOS17934.1 - 5.5e-15 54.2 50.6 0.008 15.7 0.0 14.4 17 0 0 17 17 16 7 Tetratricopeptide repeat TPR_12 PF13424.1 KOS17934.1 - 6.6e-15 54.8 51.9 0.00026 20.8 0.3 12.3 8 5 8 16 16 15 9 Tetratricopeptide repeat TPR_7 PF13176.1 KOS17934.1 - 1.9e-12 45.9 35.2 0.021 14.5 0.0 14.2 14 1 1 15 15 15 3 Tetratricopeptide repeat TPR_8 PF13181.1 KOS17934.1 - 7.7e-12 44.0 27.8 0.062 13.1 0.0 11.8 14 0 0 14 14 12 4 Tetratricopeptide repeat Apc3 PF12895.2 KOS17934.1 - 4.4e-11 42.7 15.5 0.00085 19.4 0.1 8.2 6 1 2 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KOS17934.1 - 4.7e-07 29.8 39.9 2 9.0 0.0 14.6 17 0 0 17 17 13 1 Tetratricopeptide repeat TPR_9 PF13371.1 KOS17934.1 - 5.5e-07 29.3 20.9 0.0014 18.4 0.2 7.6 6 2 0 6 6 6 2 Tetratricopeptide repeat HemY_N PF07219.8 KOS17934.1 - 0.049 13.1 9.0 0.56 9.7 0.0 5.3 5 1 1 6 6 6 0 HemY protein N-terminus Coatomer_WDAD PF04053.9 KOS17934.1 - 0.079 11.7 0.2 0.37 9.5 0.0 2.1 2 1 1 3 3 3 0 Coatomer WD associated region Fis1_TPR_C PF14853.1 KOS17934.1 - 0.094 12.6 5.8 6.2 6.7 0.1 6.2 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.5 KOS17934.1 - 0.15 10.8 0.1 29 3.2 0.0 3.3 5 0 0 5 5 5 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 KOS17934.1 - 3.1 7.8 28.7 3.8 7.5 0.3 9.7 10 0 0 10 10 10 0 Tetratricopeptide repeat DUF1767 PF08585.7 KOS17935.1 - 4.6e-05 23.6 0.0 8.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) DNA_ligase_A_M PF01068.16 KOS17936.1 - 3.8e-48 163.5 0.1 1.5e-45 155.0 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KOS17936.1 - 1.9e-28 99.4 0.0 3.2e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KOS17936.1 - 2.4e-17 63.1 0.0 1.6e-16 60.4 0.0 2.4 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 KOS17936.1 - 0.015 15.0 0.0 0.062 12.9 0.0 1.8 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain PCI_Csn8 PF10075.4 KOS17937.1 - 2.9e-32 111.4 0.0 4e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KOS17937.1 - 2.8e-21 76.0 0.1 3.8e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family BolA PF01722.13 KOS17938.1 - 1.6e-20 72.8 0.0 1.9e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Adaptin_N PF01602.15 KOS17939.1 - 8e-146 486.4 6.4 1.1e-145 485.9 4.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KOS17939.1 - 3.2e-25 89.0 2.1 4e-24 85.4 0.0 2.6 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KOS17939.1 - 3.5e-17 62.4 0.4 4.7e-07 29.9 0.0 5.0 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.17 KOS17939.1 - 8e-12 44.1 3.2 0.0076 16.2 0.0 5.9 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 KOS17939.1 - 0.00023 21.5 1.7 2 9.0 0.0 5.6 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 KOS17939.1 - 0.018 14.4 0.6 1.5 8.1 0.0 3.1 2 1 1 3 3 3 0 CLASP N terminal Atx10homo_assoc PF09759.4 KOS17939.1 - 0.037 13.7 0.0 0.64 9.7 0.0 2.7 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 KOS17939.1 - 0.063 13.1 0.7 5.8 6.8 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Bcl-2 PF00452.14 KOS17939.1 - 0.21 11.6 2.0 0.42 10.7 0.0 2.5 3 0 0 3 3 3 0 Apoptosis regulator proteins, Bcl-2 family SNF2_N PF00176.18 KOS17940.1 - 2.7e-71 239.8 1.4 5.5e-71 238.7 1.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 KOS17940.1 - 1.7e-50 170.6 16.6 1.7e-50 170.6 11.5 5.4 3 2 1 5 5 5 1 DNA-binding domain Helicase_C PF00271.26 KOS17940.1 - 3.5e-16 58.8 0.0 8.1e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ASFV_J13L PF05568.6 KOS17940.1 - 0.019 14.5 0.1 0.051 13.1 0.1 1.7 1 0 0 1 1 1 0 African swine fever virus J13L protein Kinesin PF00225.18 KOS17941.1 - 2.6e-107 358.4 3.4 6e-107 357.2 2.3 1.6 1 0 0 1 1 1 1 Kinesin motor domain WEMBL PF05701.6 KOS17941.1 - 0.00022 19.8 22.8 0.00022 19.8 15.8 3.3 2 1 1 3 3 3 2 Weak chloroplast movement under blue light DivIC PF04977.10 KOS17941.1 - 0.17 11.3 0.1 0.17 11.3 0.0 4.4 2 1 1 4 4 4 0 Septum formation initiator Reo_sigmaC PF04582.7 KOS17941.1 - 0.27 10.3 15.3 0.13 11.4 1.6 3.4 2 1 0 3 3 3 0 Reovirus sigma C capsid protein TP_methylase PF00590.15 KOS17942.1 - 1.3e-20 74.0 0.0 2.2e-20 73.2 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.3 KOS17943.1 - 3.1e-08 33.5 0.1 5.8e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1777 PF08648.7 KOS17943.1 - 7.1e-05 22.6 15.2 7.1e-05 22.6 10.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-met PF12874.2 KOS17943.1 - 0.00015 21.8 0.4 0.00027 21.0 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 KOS17943.1 - 0.02 14.5 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 DBF zinc finger CPSF100_C PF13299.1 KOS17943.1 - 0.17 12.0 6.0 0.19 11.9 2.3 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Caldesmon PF02029.10 KOS17943.1 - 2.3 6.5 29.6 0.26 9.6 16.1 1.9 2 0 0 2 2 2 0 Caldesmon Cullin PF00888.17 KOS17945.1 - 2.4e-203 676.9 14.7 3.2e-203 676.5 10.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KOS17945.1 - 1.3e-26 92.2 4.9 1.3e-26 92.2 3.4 3.2 3 0 0 3 3 3 1 Cullin protein neddylation domain TrmE_N PF10396.4 KOS17945.1 - 0.015 15.2 0.1 0.19 11.6 0.0 2.7 3 0 0 3 3 3 0 GTP-binding protein TrmE N-terminus MutS_III PF05192.13 KOS17945.1 - 0.059 13.1 3.9 0.22 11.3 0.1 2.7 2 1 0 2 2 2 0 MutS domain III WAC_Acf1_DNA_bd PF10537.4 KOS17945.1 - 0.15 12.2 3.8 0.16 12.1 0.1 3.1 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal Avl9 PF09794.4 KOS17946.1 - 2.1e-142 474.1 0.0 3.2e-142 473.5 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 KOS17946.1 - 4e-05 23.0 7.3 0.00033 20.0 0.2 3.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 KOS17946.1 - 4.9e-05 23.0 0.2 0.0057 16.3 0.0 2.3 1 1 0 2 2 2 1 Stabilization of polarity axis Med15 PF09606.5 KOS17946.1 - 0.0036 15.6 7.3 0.0046 15.2 5.1 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal APC_CDC26 PF10471.4 KOS17946.1 - 0.0049 17.5 11.6 0.02 15.6 8.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Ndc1_Nup PF09531.5 KOS17946.1 - 0.29 9.4 1.8 0.44 8.9 1.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Acyltransferase PF01553.16 KOS17947.1 - 0.0022 17.4 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Phosphorylase PF00343.15 KOS17948.1 - 0 1076.1 0.0 0 1075.9 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 KOS17948.1 - 0.03 14.0 0.0 0.12 12.0 0.0 2.1 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Pkinase PF00069.20 KOS17949.1 - 6.8e-64 215.5 0.0 8.9e-63 211.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17949.1 - 1.1e-26 93.4 0.0 3.5e-25 88.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KOS17949.1 - 6.8e-05 22.0 0.1 0.013 14.6 0.0 2.2 1 1 1 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KOS17949.1 - 0.00035 19.6 0.0 0.047 12.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 KOS17949.1 - 0.00036 20.3 0.0 0.0015 18.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KOS17949.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family CorA PF01544.13 KOS17950.1 - 2.1e-05 23.7 0.1 4e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Pyridox_oxidase PF01243.15 KOS17951.1 - 4.1e-10 39.5 0.0 7.8e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ATP-synt_F PF01990.12 KOS17952.1 - 3e-32 110.8 0.1 3.5e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.10 KOS17953.1 - 1.2e-26 93.5 0.3 1.5e-26 93.2 0.2 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KOS17953.1 - 0.00023 21.1 0.1 0.0007 19.6 0.1 1.8 1 1 0 1 1 1 1 ML-like domain PHD PF00628.24 KOS17954.1 - 2.6e-07 30.2 9.0 2.6e-07 30.2 6.2 1.8 2 0 0 2 2 2 1 PHD-finger SET PF00856.23 KOS17954.1 - 1.2e-05 25.6 3.1 2.1e-05 24.8 0.0 2.7 3 1 0 3 3 3 1 SET domain Glycos_transf_4 PF00953.16 KOS17955.1 - 2.2e-28 99.0 10.2 2.2e-28 99.0 7.0 2.0 3 0 0 3 3 3 1 Glycosyl transferase family 4 Methyltransf_16 PF10294.4 KOS17956.1 - 3.1e-10 39.7 0.0 0.00026 20.5 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase amfpi-1 PF12190.3 KOS17956.1 - 4.7 7.7 8.5 2.5 8.6 2.2 2.3 2 0 0 2 2 2 0 Fungal protease inhibitor Aconitase PF00330.15 KOS17957.1 - 1.2e-178 594.4 0.0 1.4e-178 594.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KOS17957.1 - 1.6e-44 151.1 0.0 2.7e-44 150.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain TPR_10 PF13374.1 KOS17958.1 - 0.00042 20.1 0.8 0.38 10.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat ALMS_motif PF15309.1 KOS17958.1 - 0.025 14.4 1.0 0.025 14.4 0.7 1.5 2 0 0 2 2 2 0 ALMS motif DUF2418 PF10332.4 KOS17959.1 - 7.4e-34 116.0 0.2 1.5e-33 115.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DUF2737 PF10930.3 KOS17959.1 - 0.066 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) NADH-u_ox-rdase PF10785.4 KOS17959.1 - 0.084 13.1 0.0 0.58 10.4 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit ILVD_EDD PF00920.16 KOS17960.1 - 5.9e-208 691.5 0.1 6.7e-208 691.3 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family GTP_EFTU_D4 PF14578.1 KOS17960.1 - 0.22 11.2 2.0 15 5.2 0.0 3.4 3 0 0 3 3 3 0 Elongation factor Tu domain 4 ABC_tran PF00005.22 KOS17961.1 - 6.7e-53 178.6 0.1 3.5e-30 105.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KOS17961.1 - 1.4e-31 109.9 20.7 2.6e-17 63.1 1.0 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KOS17961.1 - 1.4e-10 40.7 2.2 0.011 15.0 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KOS17961.1 - 1.8e-10 41.3 0.0 0.013 15.4 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KOS17961.1 - 5.9e-09 35.6 0.0 0.00025 20.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KOS17961.1 - 8.5e-09 34.8 1.7 0.0009 18.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KOS17961.1 - 2.5e-08 34.5 1.0 9.7e-06 26.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KOS17961.1 - 2.2e-06 26.9 0.2 0.0028 16.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KOS17961.1 - 4.8e-06 26.1 0.0 0.03 13.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 KOS17961.1 - 1.3e-05 24.7 0.2 0.053 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 KOS17961.1 - 7.4e-05 22.9 0.5 0.36 10.9 0.1 3.3 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KOS17961.1 - 7.7e-05 23.5 0.3 0.94 10.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KOS17961.1 - 7.9e-05 22.5 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KOS17961.1 - 0.00011 22.6 0.1 0.46 10.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein T2SE PF00437.15 KOS17961.1 - 0.00011 21.1 0.0 0.19 10.5 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein NB-ARC PF00931.17 KOS17961.1 - 0.00024 20.0 0.0 0.19 10.5 0.0 2.6 3 0 0 3 3 3 2 NB-ARC domain DUF87 PF01935.12 KOS17961.1 - 0.00024 20.9 2.3 0.0047 16.7 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 KOS17961.1 - 0.00029 20.5 0.9 0.085 12.5 0.1 3.1 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KOS17961.1 - 0.00048 19.9 1.3 0.72 9.6 0.0 2.5 2 0 0 2 2 2 2 Dynamin family NACHT PF05729.7 KOS17961.1 - 0.00085 19.0 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.1 KOS17961.1 - 0.0014 18.3 0.1 0.49 10.1 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain SbcCD_C PF13558.1 KOS17961.1 - 0.002 18.0 0.0 2.6 8.0 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KOS17961.1 - 0.0024 18.1 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KOS17961.1 - 0.003 17.0 0.6 1.2 8.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KOS17961.1 - 0.0056 16.6 6.1 0.93 9.4 0.1 3.2 2 1 0 3 3 3 2 AAA ATPase domain Viral_helicase1 PF01443.13 KOS17961.1 - 0.0082 15.6 0.0 4.8 6.6 0.0 2.6 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 KOS17961.1 - 0.0092 15.7 0.6 2 8.0 0.1 2.4 2 0 0 2 2 2 1 NTPase AAA_15 PF13175.1 KOS17961.1 - 0.01 14.9 0.0 0.024 13.7 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 KOS17961.1 - 0.014 15.3 0.0 5.1 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 KOS17961.1 - 0.017 14.4 1.5 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein DAP3 PF10236.4 KOS17961.1 - 0.046 12.6 1.4 3.6 6.4 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ABC_ATPase PF09818.4 KOS17961.1 - 0.049 12.2 1.7 2.6 6.5 0.1 3.4 4 0 0 4 4 4 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 KOS17961.1 - 0.067 12.2 0.1 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 KOS17961.1 - 0.08 12.8 0.0 4.6 7.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain Septin PF00735.13 KOS17961.1 - 0.096 11.6 0.1 7.2 5.5 0.0 2.4 2 0 0 2 2 2 0 Septin DUF2075 PF09848.4 KOS17961.1 - 0.11 11.4 0.1 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.12 KOS17961.1 - 0.12 11.8 0.4 3.7 7.0 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 KOS17961.1 - 0.19 11.3 0.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase EF-hand_7 PF13499.1 KOS17962.1 - 5.9e-29 100.0 13.6 2.6e-13 49.8 0.9 3.3 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 KOS17962.1 - 2.2e-24 82.8 14.3 3e-08 32.3 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 KOS17962.1 - 2.8e-23 79.6 4.7 7.1e-06 25.4 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 KOS17962.1 - 8.4e-17 59.6 15.9 2.3e-05 23.5 0.0 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 KOS17962.1 - 1.7e-13 49.9 15.1 9e-05 22.0 1.3 4.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KOS17962.1 - 8e-09 35.1 9.3 0.0043 16.7 0.1 4.0 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KOS17962.1 - 2.3e-05 24.2 0.6 0.022 14.6 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 KOS17962.1 - 0.0009 19.2 2.6 0.56 10.2 0.2 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Toprim PF01751.17 KOS17962.1 - 0.011 15.7 0.0 3.9 7.5 0.0 2.3 1 1 1 2 2 2 0 Toprim domain DUF1679 PF07914.6 KOS17962.1 - 0.015 13.9 0.6 2.1 6.8 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_2 PF09068.6 KOS17962.1 - 0.02 14.9 0.2 2.9 7.9 0.0 3.1 3 1 0 3 3 3 0 EF hand EF-hand_10 PF14788.1 KOS17962.1 - 0.021 14.4 5.4 0.65 9.6 0.0 4.0 5 0 0 5 5 5 0 EF hand Acyl-CoA_dh_1 PF00441.19 KOS17963.1 - 1.8e-40 138.4 0.3 2.5e-40 138.0 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KOS17963.1 - 2.9e-21 76.1 0.0 6.5e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KOS17963.1 - 1.1e-20 72.8 0.3 2e-20 72.0 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 KOS17963.1 - 4.8e-19 67.9 0.1 9.3e-19 67.0 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 KOS17963.1 - 3.1e-08 33.9 0.0 5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain XPG_I PF00867.13 KOS17964.1 - 5.7e-30 103.2 0.0 1.3e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KOS17964.1 - 6.3e-19 68.1 0.0 6.3e-19 68.1 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KOS17964.1 - 3e-06 27.3 0.8 8.5e-06 25.9 0.0 2.1 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.2 KOS17964.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 XPG domain containing TniB PF05621.6 KOS17964.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein DSBA PF01323.15 KOS17965.1 - 2e-16 60.1 0.0 7.1e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 DSBA-like thioredoxin domain adh_short PF00106.20 KOS17966.1 - 8e-19 68.1 0.0 1.6e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS17966.1 - 1.4e-06 28.2 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS17966.1 - 2.1e-05 24.2 0.0 3.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KOS17966.1 - 0.006 16.6 0.0 0.052 13.5 0.0 2.1 2 1 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KOS17966.1 - 0.055 13.2 0.7 0.21 11.4 0.5 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KOS17966.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pkinase PF00069.20 KOS17967.1 - 5.3e-65 219.1 0.0 6.4e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS17967.1 - 1.7e-35 122.3 0.0 2.3e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS17967.1 - 0.00058 18.8 0.0 0.0014 17.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS17967.1 - 0.056 13.1 0.9 0.17 11.5 0.6 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family MSP1_C PF07462.6 KOS17967.1 - 0.77 8.0 3.2 1 7.6 2.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Occludin_ELL PF07303.8 KOS17968.1 - 0.017 15.8 3.8 0.017 15.8 2.7 4.7 2 1 2 4 4 4 0 Occludin homology domain HiaBD2 PF15403.1 KOS17968.1 - 0.65 10.1 4.0 2.2 8.4 0.3 3.5 4 0 0 4 4 4 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) Mitofilin PF09731.4 KOS17968.1 - 1.9 7.0 47.0 3.5 6.1 0.3 2.4 2 1 0 2 2 2 0 Mitochondrial inner membrane protein Birna_VP5 PF03042.9 KOS17968.1 - 4.4 6.8 8.5 7.8 5.9 0.2 2.9 3 0 0 3 3 3 0 Birnavirus VP5 protein DUF1993 PF09351.5 KOS17968.1 - 8 6.3 11.9 8.4 6.2 0.8 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) CorA PF01544.13 KOS17968.1 - 9.3 5.1 8.5 1.4 7.9 2.6 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein 4HBT PF03061.17 KOS17969.1 - 8.9e-10 38.5 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KOS17969.1 - 0.0048 16.6 0.0 0.0085 15.8 0.0 1.4 2 0 0 2 2 2 1 Thioesterase-like superfamily DUF4442 PF14539.1 KOS17969.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4442) NAD_binding_4 PF07993.7 KOS17970.1 - 3.6e-23 81.7 0.0 5.2e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein FAD_binding_7 PF03441.9 KOS17971.1 - 5.7e-84 281.5 0.0 7.6e-84 281.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KOS17971.1 - 1.3e-37 129.1 0.3 5.5e-37 127.0 0.2 1.9 2 0 0 2 2 2 1 DNA photolyase p12I PF12233.3 KOS17971.1 - 0.06 13.6 0.0 8 6.8 0.0 2.5 2 0 0 2 2 2 0 Human adult T cell leukemia/lymphoma virus protein MutS_V PF00488.16 KOS17972.1 - 1.8e-96 322.1 0.0 2.5e-96 321.6 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KOS17972.1 - 2e-37 128.9 0.2 4e-37 128.0 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 KOS17972.1 - 3.4e-24 85.4 1.0 6.5e-23 81.3 0.0 3.1 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 KOS17972.1 - 7.1e-13 48.5 1.4 3.9e-12 46.1 0.6 2.6 2 0 0 2 2 2 1 MutS family domain IV Tim17 PF02466.14 KOS17973.1 - 1.7e-05 24.8 6.6 5.2e-05 23.3 4.6 1.8 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family tRNA_m1G_MT PF01746.16 KOS17974.1 - 4.3e-32 111.2 0.0 5.6e-24 84.7 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase TFIIA PF03153.8 KOS17974.1 - 0.0004 20.4 0.1 0.00057 19.9 0.1 1.2 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.7 KOS17974.1 - 0.19 10.9 10.7 0.37 10.0 7.4 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_primase_S PF01896.14 KOS17975.1 - 6.6e-54 181.6 0.2 1.2e-53 180.7 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Response_reg PF00072.19 KOS17976.1 - 3.1e-22 78.6 0.0 6.3e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HSF_DNA-bind PF00447.12 KOS17976.1 - 1.4e-12 47.6 0.1 2.9e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding DUF972 PF06156.8 KOS17976.1 - 0.03 14.6 0.7 0.03 14.6 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Zip PF02535.17 KOS17976.1 - 0.38 9.6 2.0 0.61 9.0 1.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Secretin_N_2 PF07655.8 KOS17976.1 - 8 6.9 10.0 1.4 9.3 0.5 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain GTP_EFTU PF00009.22 KOS17977.1 - 2.6e-38 131.3 4.4 1.6e-37 128.7 3.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KOS17977.1 - 4.4e-26 90.9 0.4 1.2e-25 89.4 0.2 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KOS17977.1 - 3e-12 46.4 2.3 1.5e-06 28.2 0.0 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KOS17977.1 - 6.3e-08 32.5 0.1 1.7e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KOS17977.1 - 1.3e-06 28.8 0.1 4.6e-06 27.1 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS17977.1 - 9.5e-06 24.9 0.0 1.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 KOS17977.1 - 5.1e-05 22.7 0.5 0.00014 21.3 0.3 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 KOS17977.1 - 5.2e-05 22.5 0.5 0.00015 21.0 0.4 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 KOS17977.1 - 0.00025 20.3 0.3 0.00073 18.8 0.2 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit IF2_N PF04760.10 KOS17977.1 - 0.0047 16.5 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region ATP_bind_1 PF03029.12 KOS17977.1 - 0.0079 15.7 0.0 0.027 13.9 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein ResIII PF04851.10 KOS17977.1 - 0.041 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DBINO PF13892.1 KOS17977.1 - 0.19 11.7 7.9 0.5 10.3 5.5 1.7 1 0 0 1 1 1 0 DNA-binding domain Dynamin_N PF00350.18 KOS17977.1 - 1.6 8.5 6.0 11 5.8 0.0 3.2 3 1 1 4 4 4 0 Dynamin family RR_TM4-6 PF06459.7 KOS17977.1 - 6.2 6.6 14.3 0.57 10.0 5.2 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF367 PF04034.8 KOS17978.1 - 1.4e-47 160.4 0.0 2e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KOS17978.1 - 3.2e-12 45.8 1.0 7e-12 44.7 0.7 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AIM24 PF01987.12 KOS17979.1 - 3.2e-42 144.4 0.0 4.1e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF915 PF06028.6 KOS17979.1 - 0.041 12.9 0.1 0.057 12.4 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Kinesin PF00225.18 KOS17980.1 - 5.1e-82 275.2 0.0 5.1e-82 275.2 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain HHH_3 PF12836.2 KOS17980.1 - 0.0034 17.3 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif RAP1 PF07218.6 KOS17980.1 - 0.018 13.2 5.0 0.029 12.4 3.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pacs-1 PF10254.4 KOS17981.1 - 0.16 10.5 0.2 0.19 10.3 0.1 1.0 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Daxx PF03344.10 KOS17982.1 - 0.071 11.6 22.0 0.1 11.0 15.2 1.1 1 0 0 1 1 1 0 Daxx Family eIF-3c_N PF05470.7 KOS17982.1 - 0.1 10.6 6.5 6.1 4.8 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.7 KOS17982.1 - 0.44 8.4 24.1 0.66 7.8 16.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 KOS17982.1 - 4.4 6.2 20.6 6.7 5.6 14.3 1.2 1 0 0 1 1 1 0 BUD22 GFA PF04828.9 KOS17983.1 - 0.00054 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KOS17983.1 - 0.12 11.6 0.4 0.12 11.6 0.3 1.7 2 0 0 2 2 2 0 zinc-ribbon domain AMP-binding PF00501.23 KOS17984.1 - 4e-70 236.3 0.0 4.9e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS17984.1 - 9.5e-16 58.5 0.0 2.3e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain OKR_DC_1_N PF03709.10 KOS17984.1 - 0.11 12.5 0.0 0.57 10.2 0.0 2.0 1 1 1 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Glyco_hydro_1 PF00232.13 KOS17986.1 - 8.2e-142 472.5 0.0 9.7e-142 472.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Helicase_C_3 PF13625.1 KOS17987.1 - 1.1e-25 89.8 0.0 2.9e-24 85.2 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS17987.1 - 2.1e-14 53.8 0.0 4.8e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KOS17987.1 - 4e-10 38.9 0.0 6.4e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS17987.1 - 4.1e-10 39.3 0.0 9.7e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CHY PF05495.7 KOS17988.1 - 3e-14 52.9 22.5 3.9e-14 52.5 15.6 1.1 1 0 0 1 1 1 1 CHY zinc finger zf-RING_3 PF14369.1 KOS17988.1 - 0.077 13.0 2.7 0.077 13.0 1.9 2.6 1 1 1 2 2 2 0 zinc-finger C1_4 PF07975.7 KOS17988.1 - 0.087 12.8 15.7 0.48 10.4 5.1 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain DUF3797 PF12677.2 KOS17988.1 - 0.59 9.7 0.0 0.59 9.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) Zn_Tnp_IS1595 PF12760.2 KOS17988.1 - 0.69 9.7 14.7 9.6 6.1 7.5 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 KOS17988.1 - 1.8 8.6 13.8 2.8 7.9 5.5 2.5 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.14 KOS17988.1 - 4.3 7.0 13.1 0.14 11.8 3.2 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family VPS9 PF02204.13 KOS17989.1 - 4.9e-23 81.1 0.0 9.6e-23 80.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain K_oxygenase PF13434.1 KOS17989.1 - 0.16 10.8 1.8 0.32 9.8 0.3 1.7 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkH PF02386.11 KOS17990.1 - 6.6e-111 370.2 9.4 6.6e-111 370.2 6.5 1.9 2 0 0 2 2 2 1 Cation transport protein RRM_6 PF14259.1 KOS17991.1 - 1.4e-11 44.1 0.2 2.7e-10 40.0 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS17991.1 - 2.9e-08 33.2 0.1 0.00057 19.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS17991.1 - 2.8e-07 30.2 0.0 4.7e-05 23.1 0.1 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 KOS17991.1 - 1.8e-06 27.9 0.0 3.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 KOS17991.1 - 3.7e-05 23.2 5.0 6.7e-05 22.4 3.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.1 KOS17991.1 - 5.6e-05 22.8 0.0 0.042 13.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Herpes_LMP1 PF05297.6 KOS17991.1 - 0.25 10.2 5.9 2.5 6.9 1.4 2.2 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) MTHFR PF02219.12 KOS17992.1 - 1.2e-114 382.2 0.0 1.6e-114 381.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase LRR_4 PF12799.2 KOS17993.1 - 4.2e-18 64.5 14.9 4.7e-06 26.0 0.7 4.9 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS17993.1 - 2.7e-10 39.8 9.7 4.2e-07 29.6 2.0 3.6 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 KOS17993.1 - 8.4e-10 37.3 9.4 0.33 11.1 0.1 6.7 6 1 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 KOS17993.1 - 2.8e-05 23.7 5.1 21 5.5 0.0 5.7 4 1 1 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 KOS17993.1 - 0.00027 20.6 9.6 18 6.0 0.1 6.4 6 1 0 6 6 6 1 Leucine rich repeat Glyco_transf_90 PF05686.7 KOS17994.1 - 1.2e-11 43.9 0.5 0.0012 17.5 0.0 4.1 4 0 0 4 4 4 4 Glycosyl transferase family 90 Hydrophobin PF01185.13 KOS17995.1 - 7.5e-14 51.9 8.4 9.7e-14 51.5 5.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Arginase PF00491.16 KOS17996.1 - 8.9e-75 251.5 0.5 1e-74 251.3 0.4 1.0 1 0 0 1 1 1 1 Arginase family Ribosomal_S13 PF00416.17 KOS17997.1 - 2.7e-22 79.2 0.0 3.4e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 MARVEL PF01284.18 KOS17998.1 - 0.032 14.0 19.8 0.14 11.9 13.7 2.1 1 1 0 1 1 1 0 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 KOS17998.1 - 0.074 12.7 23.5 0.1 12.2 10.3 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF3733 PF12534.3 KOS17998.1 - 0.094 12.0 1.4 0.25 10.6 1.0 1.8 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 CCSMST1 PF15013.1 KOS17998.1 - 0.4 10.6 1.6 1.2 9.0 1.1 1.8 1 0 0 1 1 1 0 CCSMST1 family FCH PF00611.18 KOS17999.1 - 2.7e-16 59.5 0.1 4.9e-15 55.4 0.0 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 KOS17999.1 - 8.3e-15 54.7 0.0 1.7e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.16 KOS17999.1 - 1.7e-11 43.6 0.0 3.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) KIP1 PF07765.7 KOS17999.1 - 0.0032 17.2 0.0 0.18 11.6 0.0 2.6 2 0 0 2 2 2 1 KIP1-like protein EB1 PF03271.12 KOS17999.1 - 0.4 10.7 2.0 5.9 7.0 1.4 2.5 1 1 0 1 1 1 0 EB1-like C-terminal motif DUF1993 PF09351.5 KOS18000.1 - 8.4e-36 123.3 0.0 9.5e-36 123.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF2859 PF11072.3 KOS18000.1 - 0.042 13.3 0.1 0.085 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) Trm112p PF03966.11 KOS18001.1 - 1.9e-16 60.1 0.2 2.4e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein DUF1479 PF07350.7 KOS18002.1 - 1.3e-153 511.4 0.0 1.5e-153 511.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Pro_isomerase PF00160.16 KOS18003.1 - 2.4e-46 157.7 1.0 3.1e-46 157.4 0.7 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD N-SET PF11764.3 KOS18004.1 - 3.9e-42 144.0 0.0 3.9e-42 144.0 0.0 2.3 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 KOS18004.1 - 6.1e-23 81.8 0.2 6.1e-23 81.8 0.1 3.3 2 2 0 2 2 2 1 SET domain Suf PF05843.9 KOS18004.1 - 2.5 7.7 10.9 0.57 9.8 4.7 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Tropomyosin_1 PF12718.2 KOS18005.1 - 1.6e-44 151.2 34.9 2.1e-44 150.8 24.2 1.2 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KOS18005.1 - 5.8e-09 35.3 32.0 2.9e-06 26.5 11.1 2.1 1 1 1 2 2 2 2 Tropomyosin ATG16 PF08614.6 KOS18005.1 - 0.00084 19.2 31.1 0.044 13.5 9.7 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.4 KOS18005.1 - 0.0017 18.4 21.9 0.07 13.2 3.8 3.0 1 1 1 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.7 KOS18005.1 - 0.0018 16.5 7.4 0.0018 16.5 5.1 2.1 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.4 KOS18005.1 - 0.0028 17.5 8.3 0.0028 17.5 5.7 3.1 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 KOS18005.1 - 0.006 16.5 36.7 0.021 14.7 11.7 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) GAS PF13851.1 KOS18005.1 - 0.025 13.7 33.3 0.056 12.6 13.0 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Cep57_MT_bd PF06657.8 KOS18005.1 - 0.039 13.9 1.3 0.039 13.9 0.9 3.2 2 2 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ADIP PF11559.3 KOS18005.1 - 0.052 13.4 32.8 1.4 8.7 9.2 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 KOS18005.1 - 0.065 12.2 35.0 0.037 13.0 15.0 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Myosin_tail_1 PF01576.14 KOS18005.1 - 0.14 9.8 34.9 0.22 9.2 24.2 1.3 1 1 0 1 1 1 0 Myosin tail ERM PF00769.14 KOS18005.1 - 0.22 11.0 36.3 1.4 8.4 9.4 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.14 KOS18005.1 - 0.29 8.9 18.0 0.34 8.7 12.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KLRAQ PF10205.4 KOS18005.1 - 0.33 11.0 20.5 2.7 8.0 1.1 3.2 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein IncA PF04156.9 KOS18005.1 - 0.42 10.1 32.0 3.9 7.0 22.1 1.9 1 1 0 1 1 1 0 IncA protein HalX PF08663.5 KOS18005.1 - 0.43 10.6 22.2 2.3 8.2 2.5 4.2 2 1 1 3 3 3 0 HalX domain Lebercilin PF15619.1 KOS18005.1 - 0.61 9.4 34.6 2.6 7.4 11.9 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3450 PF11932.3 KOS18005.1 - 0.63 9.2 25.5 0.68 9.1 5.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Spectrin PF00435.16 KOS18005.1 - 0.66 10.2 26.0 3 8.1 10.6 2.8 1 1 1 2 2 2 0 Spectrin repeat TarH PF02203.10 KOS18005.1 - 0.67 9.7 11.7 0.29 10.9 6.2 1.8 1 1 1 2 2 2 0 Tar ligand binding domain homologue Atg14 PF10186.4 KOS18005.1 - 0.9 8.4 27.5 0.095 11.6 15.1 1.8 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 KOS18005.1 - 0.99 9.4 28.3 0.23 11.4 2.0 4.5 1 1 3 4 4 4 0 bZIP transcription factor Fib_alpha PF08702.5 KOS18005.1 - 1.2 9.2 19.4 0.35 10.9 3.7 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.3 KOS18005.1 - 1.4 6.1 29.0 1.7 5.8 20.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin-6_N PF09177.6 KOS18005.1 - 1.8 9.0 18.1 1.8 9.0 3.1 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal BRE1 PF08647.6 KOS18005.1 - 1.8 8.5 30.3 0.033 14.1 6.5 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase AAA_13 PF13166.1 KOS18005.1 - 2 6.7 26.2 5.6 5.2 18.1 1.6 1 1 0 1 1 1 0 AAA domain Jnk-SapK_ap_N PF09744.4 KOS18005.1 - 2 8.3 30.2 0.052 13.5 9.1 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Striatin PF08232.7 KOS18005.1 - 2.2 8.5 24.8 4.9 7.4 7.5 2.2 1 1 1 2 2 2 0 Striatin family Prefoldin_2 PF01920.15 KOS18005.1 - 2.9 7.6 34.2 0.23 11.2 4.1 3.9 2 1 3 5 5 5 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 KOS18005.1 - 3.4 7.4 34.0 5.6 6.7 6.8 2.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 KOS18005.1 - 3.7 6.1 29.3 0.85 8.2 9.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2360 PF10152.4 KOS18005.1 - 3.8 7.7 9.1 2.8 8.2 1.0 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF4201 PF13870.1 KOS18005.1 - 3.9 6.8 32.0 0.94 8.8 17.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) PilJ PF13675.1 KOS18005.1 - 4.8 7.5 11.7 3 8.1 3.4 2.6 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Seryl_tRNA_N PF02403.17 KOS18005.1 - 5.8 6.9 26.5 2 8.4 8.6 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.3 KOS18005.1 - 8.7 6.2 34.8 20 5.0 9.7 3.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4202 PF13875.1 KOS18006.1 - 4.5e-29 101.3 0.0 5.2e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) PPR_2 PF13041.1 KOS18008.1 - 2.9e-48 161.5 1.9 2.2e-09 37.1 0.0 13.7 10 5 5 15 15 15 9 PPR repeat family PPR PF01535.15 KOS18008.1 - 1.5e-25 87.3 15.3 0.00078 19.2 0.0 13.7 16 0 0 16 16 16 6 PPR repeat PPR_3 PF13812.1 KOS18008.1 - 2.4e-24 83.5 23.7 0.0038 17.3 0.0 15.5 17 0 0 17 17 17 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 KOS18008.1 - 1.2e-22 79.0 5.4 3.8e-09 35.8 0.0 11.0 10 2 0 10 10 10 3 PPR repeat RPM2 PF08579.6 KOS18008.1 - 4.3e-07 30.0 0.0 0.0001 22.3 0.0 3.9 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) GPP34 PF05719.6 KOS18008.1 - 0.0028 17.7 0.1 0.024 14.7 0.0 2.4 2 0 0 2 2 2 1 Golgi phosphoprotein 3 (GPP34) ECSIT PF06239.6 KOS18008.1 - 0.053 12.3 0.0 5.5 5.7 0.0 2.8 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway FRD2 PF03197.8 KOS18008.1 - 0.2 12.2 0.0 0.69 10.4 0.0 1.9 1 0 0 1 1 1 0 Bacteriophage FRD2 protein GHMP_kinases_N PF00288.21 KOS18009.1 - 1.3e-15 57.1 1.8 1.3e-15 57.1 1.2 2.8 1 1 1 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KOS18009.1 - 9.7e-09 35.3 0.1 5.2e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal DEAD PF00270.24 KOS18010.1 - 3.1e-40 137.4 0.0 4.9e-40 136.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS18010.1 - 2.7e-18 65.5 0.0 5.6e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KOS18010.1 - 4.2e-16 58.2 0.0 9.6e-16 57.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KOS18010.1 - 0.002 17.9 0.0 0.0049 16.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Alkyl_sulf_dimr PF14863.1 KOS18011.1 - 6.8e-57 191.6 0.0 1.6e-56 190.4 0.0 1.6 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.1 KOS18011.1 - 5.1e-29 100.7 0.0 9e-29 99.9 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.22 KOS18011.1 - 2e-21 76.5 0.0 3.3e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily TPR_11 PF13414.1 KOS18011.1 - 1.2e-05 24.8 0.3 2.9e-05 23.6 0.2 1.6 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 KOS18011.1 - 0.00022 21.8 0.0 0.00054 20.5 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Lactamase_B_2 PF12706.2 KOS18011.1 - 0.00024 20.6 0.0 0.00067 19.2 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain SporV_AA PF12164.3 KOS18011.1 - 0.058 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AA Senescence PF06911.7 KOS18012.1 - 0.00011 22.0 5.1 0.00013 21.7 3.5 1.1 1 0 0 1 1 1 1 Senescence-associated protein DUF4175 PF13779.1 KOS18012.1 - 6.2 4.3 9.6 7 4.2 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) tRNA-synt_2 PF00152.15 KOS18013.1 - 1.2e-72 244.5 0.0 1.8e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KOS18013.1 - 3.9e-09 36.2 0.1 6.8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ten1_2 PF15490.1 KOS18013.1 - 0.088 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit CDC45 PF02724.9 KOS18013.1 - 2.2 6.2 5.7 2.7 5.9 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein GTP_EFTU PF00009.22 KOS18014.1 - 1.6e-50 171.1 0.0 2.5e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KOS18014.1 - 2.6e-19 68.8 0.0 5.5e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KOS18014.1 - 1.3e-13 50.5 0.0 1.2e-12 47.4 0.0 2.3 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KOS18014.1 - 7.1e-06 26.0 0.0 2.2e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 COPI_assoc PF08507.5 KOS18015.1 - 1.4e-39 134.9 9.4 1.6e-39 134.7 6.5 1.0 1 0 0 1 1 1 1 COPI associated protein Cytochrom_B558a PF05038.8 KOS18015.1 - 0.15 11.6 1.0 0.28 10.8 0.7 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Cg6151-P PF10233.4 KOS18015.1 - 0.3 11.0 7.6 0.55 10.2 5.2 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P Ycf66_N PF07444.6 KOS18015.1 - 1.8 8.3 6.1 1.3 8.8 2.1 2.3 1 1 1 2 2 2 0 Ycf66 protein N-terminus SUN PF03856.8 KOS18017.1 - 4e-73 245.7 11.3 6.8e-73 245.0 7.8 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF605 PF04652.11 KOS18017.1 - 5.2 6.3 26.9 8.4 5.6 18.7 1.2 1 0 0 1 1 1 0 Vta1 like Fungal_trans PF04082.13 KOS18018.1 - 1.4e-06 27.4 0.0 2.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_2 PF00703.16 KOS18019.1 - 7.7e-12 45.6 0.0 2e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KOS18019.1 - 8.6e-09 35.1 0.1 1.9e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KOS18019.1 - 0.00084 18.3 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain SMN PF06003.7 KOS18020.1 - 0.14 11.2 7.0 0.17 10.9 4.8 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) 2-Hacid_dh_C PF02826.14 KOS18021.1 - 1.1e-47 161.5 0.0 3.7e-47 159.7 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KOS18021.1 - 3e-07 29.9 0.0 3e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KOS18021.1 - 0.0053 16.6 0.1 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DRTGG PF07085.7 KOS18021.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 DRTGG domain NPP1 PF05630.6 KOS18022.1 - 3.5e-08 33.4 0.0 2.4e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Necrosis inducing protein (NPP1) Sugar_tr PF00083.19 KOS18023.1 - 2.3e-67 227.5 22.7 3.1e-67 227.1 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS18023.1 - 1e-16 60.6 35.7 2.4e-16 59.4 24.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PP28 PF10252.4 KOS18024.1 - 3.8e-25 87.7 14.9 3.8e-25 87.7 10.3 3.3 3 0 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 CoA_trans PF01144.18 KOS18025.1 - 1.4e-99 331.6 0.8 1e-58 198.0 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Sugar_tr PF00083.19 KOS18026.1 - 2.5e-45 154.9 22.8 6.3e-41 140.3 4.2 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 KOS18026.1 - 0.00013 20.4 5.6 0.00013 20.4 3.9 1.7 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 KOS18026.1 - 0.6 8.7 41.0 0.063 11.9 10.1 3.2 1 1 3 4 4 4 0 Major Facilitator Superfamily Fungal_trans PF04082.13 KOS18027.1 - 0.015 14.1 0.7 0.46 9.3 0.1 2.7 3 0 0 3 3 3 0 Fungal specific transcription factor domain SMAP PF15477.1 KOS18029.1 - 4.8e-18 65.1 3.4 4.8e-18 65.1 2.3 5.6 3 1 0 3 3 3 1 Small acidic protein family Collagen PF01391.13 KOS18031.1 - 0.0013 18.2 6.4 0.0034 16.8 4.5 1.6 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) CLASP_N PF12348.3 KOS18032.1 - 7.3e-121 401.7 0.0 3.8e-87 291.4 0.0 2.5 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 KOS18032.1 - 0.094 12.8 0.0 26 5.2 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat Clr5 PF14420.1 KOS18032.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 Clr5 domain RhoGAP PF00620.22 KOS18033.1 - 7.1e-46 155.5 2.8 7.8e-46 155.4 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 KOS18033.1 - 8.6e-14 51.3 16.6 4e-09 36.4 1.2 2.4 2 0 0 2 2 2 2 LIM domain Desulfoferrod_N PF06397.7 KOS18033.1 - 0.084 12.2 6.8 5.1 6.5 0.5 3.5 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain zinc_ribbon_2 PF13240.1 KOS18033.1 - 0.38 10.2 8.4 0.53 9.8 0.0 4.1 4 1 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KOS18033.1 - 0.42 10.5 17.3 0.53 10.2 0.8 4.2 4 0 0 4 4 4 0 Zinc ribbon domain rRNA_processing PF08524.6 KOS18034.1 - 1.3e-06 28.2 20.5 1.7e-06 27.9 14.2 1.1 1 0 0 1 1 1 1 rRNA processing DDHD PF02862.12 KOS18034.1 - 2.7 7.7 4.6 3.4 7.3 3.2 1.2 1 0 0 1 1 1 0 DDHD domain DUF4210 PF13915.1 KOS18035.1 - 4.2e-24 84.6 0.0 1e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 KOS18035.1 - 3.8e-23 81.1 0.2 8e-23 80.0 0.2 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis PPR_2 PF13041.1 KOS18036.1 - 3.2e-16 59.0 4.6 0.0023 17.8 0.0 6.7 4 2 3 7 7 7 6 PPR repeat family PPR_3 PF13812.1 KOS18036.1 - 2.3e-13 49.2 13.6 2.4 8.6 0.0 9.8 10 0 0 10 10 10 6 Pentatricopeptide repeat domain PPR PF01535.15 KOS18036.1 - 2.2e-12 46.0 18.2 0.0024 17.7 0.0 8.4 10 0 0 10 10 10 4 PPR repeat PPR_1 PF12854.2 KOS18036.1 - 0.00024 20.4 0.3 33 4.0 0.0 4.8 5 0 0 5 5 5 1 PPR repeat PI3_PI4_kinase PF00454.22 KOS18037.1 - 7.1e-30 104.2 0.0 1.8e-29 102.9 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase YqeY PF09424.5 KOS18038.1 - 2.7e-23 82.4 6.4 3.5e-23 82.0 4.4 1.0 1 0 0 1 1 1 1 Yqey-like protein SBP_bac_7 PF03480.8 KOS18038.1 - 0.11 11.6 1.3 0.14 11.2 0.9 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Ribonuc_L-PSP PF01042.16 KOS18039.1 - 8.4e-29 99.7 0.0 9.3e-29 99.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP RuvC PF02075.12 KOS18039.1 - 0.064 13.0 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC DUF1320 PF07030.7 KOS18039.1 - 0.13 11.9 0.1 0.36 10.5 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1320) TB2_DP1_HVA22 PF03134.14 KOS18040.1 - 1e-31 108.4 3.7 1.4e-31 108.0 2.6 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4407 PF14362.1 KOS18040.1 - 0.2 10.5 0.4 3.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cupin_1 PF00190.17 KOS18041.1 - 5.1e-33 113.5 0.0 1.6e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KOS18041.1 - 3e-28 97.1 1.0 4.8e-13 48.3 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KOS18041.1 - 3.9e-10 38.9 0.1 0.00022 20.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KOS18041.1 - 3e-07 30.1 0.1 0.00016 21.3 0.0 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain 3-HAO PF06052.7 KOS18041.1 - 0.0011 18.3 0.0 0.04 13.3 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase ARD PF03079.9 KOS18041.1 - 0.0036 17.2 0.7 0.59 10.0 0.0 2.3 2 0 0 2 2 2 1 ARD/ARD' family MannoseP_isomer PF01050.13 KOS18041.1 - 0.009 15.6 0.0 0.23 11.0 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 2OG-FeII_Oxy_5 PF13759.1 KOS18041.1 - 0.013 15.7 0.1 14 6.0 0.0 3.4 2 1 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase Cupin_7 PF12973.2 KOS18041.1 - 0.014 15.1 0.3 0.095 12.5 0.1 2.4 2 1 1 3 3 3 0 ChrR Cupin-like domain GPI PF06560.6 KOS18041.1 - 0.045 12.7 0.0 0.081 11.9 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) PKD PF00801.15 KOS18041.1 - 0.099 12.3 0.3 18 5.1 0.0 2.8 2 0 0 2 2 2 0 PKD domain Clathrin PF00637.15 KOS18043.1 - 2.8e-20 72.3 2.2 1.1e-19 70.4 0.9 2.5 3 1 0 3 3 3 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 KOS18043.1 - 0.00033 20.4 0.2 0.00083 19.1 0.2 1.7 1 1 0 1 1 1 1 Ring finger domain Vps39_1 PF10366.4 KOS18043.1 - 0.023 14.7 0.4 0.18 11.8 0.1 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 NBP1 PF08537.5 KOS18043.1 - 0.059 12.5 0.1 0.099 11.8 0.1 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 TPR_12 PF13424.1 KOS18043.1 - 0.097 12.6 0.2 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps39_2 PF10367.4 KOS18043.1 - 0.098 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.1 KOS18043.1 - 0.45 10.2 2.3 1.4 8.7 1.6 1.8 1 1 0 1 1 1 0 zinc-RING finger domain GatB_N PF02934.10 KOS18044.1 - 2.6e-99 331.7 0.0 3.3e-99 331.4 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KOS18044.1 - 2.8e-09 36.8 0.0 5.7e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 GatB domain ISG65-75 PF11727.3 KOS18045.1 - 0.0047 16.0 17.6 0.0057 15.7 12.2 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein DUF883 PF05957.8 KOS18045.1 - 0.013 15.9 14.1 0.12 12.8 5.9 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 KOS18045.1 - 0.024 14.9 23.1 0.25 11.7 9.5 3.3 1 1 1 2 2 2 0 YtxH-like protein ATG_C PF09333.6 KOS18045.1 - 0.025 14.7 2.9 2.4 8.3 0.0 2.2 2 0 0 2 2 2 0 ATG C terminal domain Apolipoprotein PF01442.13 KOS18045.1 - 0.028 13.9 4.4 0.042 13.3 3.1 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CAF-1_p150 PF11600.3 KOS18045.1 - 0.17 11.2 12.2 0.22 10.9 8.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TMPIT PF07851.8 KOS18045.1 - 0.35 9.9 2.9 0.37 9.8 2.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF2514 PF10721.4 KOS18045.1 - 0.91 9.2 14.6 2.4 7.8 9.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) KfrA_N PF11740.3 KOS18045.1 - 0.92 9.9 5.6 2.2 8.7 3.7 1.7 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term PGA2 PF07543.7 KOS18045.1 - 0.97 9.2 13.2 0.13 12.0 5.6 1.9 1 1 1 2 2 2 0 Protein trafficking PGA2 Fzo_mitofusin PF04799.8 KOS18045.1 - 1.2 8.5 3.5 2.4 7.5 2.3 1.6 1 1 0 1 1 1 0 fzo-like conserved region SR-25 PF10500.4 KOS18045.1 - 1.3 8.4 14.7 1.5 8.2 10.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3337 PF11816.3 KOS18045.1 - 1.5 8.1 9.7 1.6 8.0 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Synaptobrevin PF00957.16 KOS18045.1 - 2.7 7.6 8.5 1.5 8.4 3.2 2.1 1 1 1 2 2 2 0 Synaptobrevin Seryl_tRNA_N PF02403.17 KOS18045.1 - 3.7 7.5 12.7 13 5.8 8.6 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Tape_meas_lam_C PF09718.5 KOS18045.1 - 4.4 7.3 8.3 7.7 6.5 0.3 2.7 1 1 2 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) CAML PF14963.1 KOS18045.1 - 4.9 6.4 7.7 5.3 6.3 5.2 1.2 1 1 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand HAUS6_N PF14661.1 KOS18045.1 - 5.3 6.3 9.1 7 5.9 6.3 1.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Med12-LCEWAV PF12145.3 KOS18045.1 - 9 4.6 10.2 10 4.4 7.1 1.1 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Glyco_hydro_16 PF00722.16 KOS18046.1 - 3.5e-30 104.6 0.8 6.4e-30 103.8 0.5 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Sec7 PF01369.15 KOS18047.1 - 8e-44 149.5 0.0 1.5e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KOS18047.1 - 5e-19 68.5 0.0 1.3e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain BUD22 PF09073.5 KOS18047.1 - 0.48 9.4 15.6 1.1 8.2 10.8 1.5 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 KOS18047.1 - 1.1 7.1 25.4 1.7 6.4 17.6 1.2 1 0 0 1 1 1 0 Nop14-like family Fungal_trans PF04082.13 KOS18048.1 - 1.5e-23 82.9 0.0 3.1e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS18048.1 - 0.0002 21.2 3.6 0.00045 20.0 2.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KOS18049.1 - 4.7e-79 266.0 18.2 5.4e-79 265.8 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS18049.1 - 2.3e-32 112.0 49.4 5.8e-30 104.2 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1659 PF07872.6 KOS18049.1 - 0.088 12.4 0.1 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) zf-C3HC4 PF00097.20 KOS18050.1 - 5.9e-09 35.4 1.7 2e-08 33.7 1.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS18050.1 - 1.9e-07 30.8 5.1 4.3e-07 29.6 3.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KOS18050.1 - 2.6e-07 30.5 2.7 1.2e-06 28.4 2.1 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KOS18050.1 - 2.2e-05 24.2 4.3 0.00011 22.0 3.0 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KOS18050.1 - 2.5e-05 23.9 3.8 7e-05 22.4 2.7 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 KOS18050.1 - 7.4e-05 22.4 2.2 9.7e-05 22.0 0.6 1.9 1 1 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KOS18050.1 - 0.00018 21.1 1.4 0.00035 20.2 1.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KOS18050.1 - 0.0002 20.9 2.5 0.0004 20.0 1.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MIP-T3 PF10243.4 KOS18050.1 - 5.6 5.3 19.6 7.4 4.9 13.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Metallopep PF12044.3 KOS18051.1 - 1.3e-162 541.0 0.0 1.7e-162 540.7 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 KOS18051.1 - 3e-07 30.3 0.0 5.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.1 KOS18051.1 - 0.045 13.6 0.4 0.082 12.8 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KOS18051.1 - 0.076 12.5 0.2 0.14 11.6 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KOS18051.1 - 0.083 12.9 0.3 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CM_2 PF01817.16 KOS18052.1 - 1.2e-07 31.6 0.1 5.1e-05 23.2 0.0 3.0 2 1 0 2 2 2 2 Chorismate mutase type II WD40 PF00400.27 KOS18053.1 - 1.3e-40 135.8 6.9 6.6e-11 41.6 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KOS18053.1 - 1.4e-07 30.0 9.0 0.029 12.5 0.1 4.7 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KOS18053.1 - 0.00061 18.6 0.0 1.1 7.8 0.0 3.8 2 2 1 4 4 4 1 Nup133 N terminal like PQQ_2 PF13360.1 KOS18053.1 - 0.0024 17.3 0.5 0.09 12.2 0.0 2.5 2 1 1 3 3 3 2 PQQ-like domain BBS2_Mid PF14783.1 KOS18053.1 - 0.0094 15.7 0.0 0.38 10.5 0.0 3.4 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Seryl_tRNA_N PF02403.17 KOS18053.1 - 1.1 9.3 5.3 3.1 7.8 0.3 2.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Vps5 PF09325.5 KOS18054.1 - 3.8e-13 49.2 1.0 6e-13 48.5 0.7 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KOS18054.1 - 2.4e-06 27.3 0.0 4.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 PX domain TPR_12 PF13424.1 KOS18054.1 - 0.033 14.1 0.4 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KOS18054.1 - 0.036 14.7 0.8 6.2 7.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KOS18054.1 - 0.14 11.7 1.5 0.89 9.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KOS18054.1 - 0.33 10.9 2.1 6.5 6.9 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat NST1 PF13945.1 KOS18054.1 - 0.36 10.8 2.3 0.62 10.1 1.6 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator BCIP PF13862.1 KOS18055.1 - 2.5e-63 213.1 0.0 3.1e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein NB-ARC PF00931.17 KOS18055.1 - 0.13 11.1 0.0 0.27 10.0 0.0 1.4 2 0 0 2 2 2 0 NB-ARC domain Glyco_hydro_2_N PF02837.13 KOS18056.1 - 7.5e-30 103.6 0.0 1.6e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KOS18056.1 - 4.4e-12 45.5 0.0 7.8e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KOS18056.1 - 5.1e-10 39.7 0.0 1.2e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KOS18056.1 - 0.0043 17.3 0.1 0.011 16.0 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain MG1 PF11974.3 KOS18056.1 - 0.039 14.4 0.4 0.54 10.8 0.1 2.6 3 0 0 3 3 3 0 Alpha-2-macroglobulin MG1 domain bZIP_1 PF00170.16 KOS18057.1 - 3e-08 33.4 14.3 5.1e-08 32.7 9.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KOS18057.1 - 1e-05 25.6 6.0 1.6e-05 25.1 4.1 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor PAP1 PF08601.5 KOS18057.1 - 0.0013 18.4 0.2 0.0013 18.4 0.1 2.1 1 1 1 2 2 2 1 Transcription factor PAP1 CASP_C PF08172.7 KOS18057.1 - 0.0064 15.5 0.8 0.01 14.9 0.5 1.3 1 0 0 1 1 1 1 CASP C terminal bZIP_2 PF07716.10 KOS18057.1 - 0.017 14.9 16.2 0.024 14.4 10.7 1.6 1 1 0 1 1 1 0 Basic region leucine zipper DUF972 PF06156.8 KOS18057.1 - 0.032 14.5 0.4 0.057 13.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 KOS18057.1 - 0.088 12.7 0.7 0.18 11.7 0.5 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PRKCSH-like PF12999.2 KOS18057.1 - 0.11 12.0 0.9 0.19 11.3 0.7 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Glutaredoxin2_C PF04399.8 KOS18057.1 - 0.15 11.6 3.1 0.26 10.8 2.1 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain V_ATPase_I PF01496.14 KOS18057.1 - 0.17 9.7 1.7 0.2 9.4 1.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rootletin PF15035.1 KOS18057.1 - 0.19 11.7 8.2 0.28 11.1 5.7 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Glycos_transf_2 PF00535.21 KOS18058.1 - 2.1e-21 76.3 0.0 1.1e-20 73.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KOS18058.1 - 5.9e-11 42.6 1.3 9.3e-08 32.1 0.1 3.1 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 KOS18058.1 - 0.041 14.1 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 SE PF08491.5 KOS18059.1 - 2.2e-83 279.2 0.0 3.1e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 KOS18059.1 - 2.4e-10 40.0 0.2 5.5e-06 25.6 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KOS18059.1 - 5.3e-10 38.7 0.9 1.2e-08 34.3 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 KOS18059.1 - 5.9e-06 25.3 1.6 2.6e-05 23.2 1.1 1.8 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KOS18059.1 - 1e-05 24.8 0.6 1.5e-05 24.3 0.1 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KOS18059.1 - 1.5e-05 24.0 0.2 2.4e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KOS18059.1 - 1.6e-05 24.7 0.2 3.6e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KOS18059.1 - 3.5e-05 23.0 0.0 6.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KOS18059.1 - 0.00018 21.4 0.7 0.00055 19.8 0.4 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KOS18059.1 - 0.00054 19.0 1.5 0.29 9.9 0.0 2.4 3 0 0 3 3 3 2 Lycopene cyclase protein ApbA PF02558.11 KOS18059.1 - 0.0026 17.2 0.1 0.0046 16.4 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 KOS18059.1 - 0.0027 18.0 1.6 0.0089 16.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KOS18059.1 - 0.015 13.8 0.0 0.022 13.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 KOS18059.1 - 0.015 14.9 0.1 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KOS18059.1 - 0.022 14.8 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 KOS18059.1 - 0.031 14.0 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 KOS18059.1 - 0.051 13.4 0.8 0.13 12.0 0.2 1.8 2 0 0 2 2 2 0 ThiF family SMK-1 PF04802.10 KOS18060.1 - 6.7e-76 254.1 0.5 6.7e-76 254.1 0.3 2.2 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 SDA1 PF05285.7 KOS18060.1 - 2.9 7.0 16.6 4.7 6.4 11.5 1.2 1 0 0 1 1 1 0 SDA1 RNase_H2-Ydr279 PF09468.5 KOS18060.1 - 7 5.7 7.1 37 3.3 4.9 2.1 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Rdx PF10262.4 KOS18062.1 - 8.3e-29 99.4 0.0 1.1e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Rdx family Metallophos PF00149.23 KOS18063.1 - 1.4e-44 151.9 0.2 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 KOS18064.1 - 1.7e-17 63.2 0.0 4.4e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS18064.1 - 8.2e-05 22.4 8.8 0.00017 21.4 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dus PF01207.12 KOS18065.1 - 1.2e-55 188.5 0.0 6.7e-55 186.1 0.0 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) WSC PF01822.14 KOS18068.1 - 1.3e-40 137.1 28.0 3.8e-20 71.6 6.5 2.6 2 0 0 2 2 2 2 WSC domain PCI PF01399.22 KOS18069.1 - 1.1e-06 28.9 0.0 1.1e-06 28.9 0.0 2.7 3 0 0 3 3 3 1 PCI domain ubiquitin PF00240.18 KOS18070.1 - 2e-07 30.2 0.0 3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 KOS18070.1 - 0.045 14.3 0.0 0.062 13.8 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD G-gamma PF00631.17 KOS18071.1 - 7.4e-26 89.6 0.0 9.4e-26 89.3 0.0 1.1 1 0 0 1 1 1 1 GGL domain PAS_4 PF08448.5 KOS18073.1 - 0.033 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 PAS fold End3 PF12761.2 KOS18074.1 - 1.4e-70 236.9 3.3 2e-70 236.4 2.3 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 KOS18074.1 - 1.4e-47 159.7 0.0 4.3e-47 158.1 0.0 1.9 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KOS18074.1 - 2.7e-06 26.2 0.3 5.9e-06 25.2 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 KOS18074.1 - 8.9e-05 22.0 0.1 0.00018 21.0 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 KOS18074.1 - 0.00068 19.7 0.1 0.0034 17.4 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KOS18074.1 - 0.0041 16.8 0.3 0.022 14.6 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain HlyD PF00529.15 KOS18074.1 - 0.065 12.5 5.5 0.13 11.5 3.8 1.4 1 0 0 1 1 1 0 HlyD family secretion protein Drf_FH3 PF06367.11 KOS18074.1 - 0.16 11.3 4.9 2.6 7.4 0.2 2.5 2 0 0 2 2 2 0 Diaphanous FH3 Domain DUF2951 PF11166.3 KOS18074.1 - 9.8 6.1 12.2 17 5.3 3.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) Ribonuclease_T2 PF00445.13 KOS18075.1 - 1.1e-26 93.5 0.1 1.8e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Actin PF00022.14 KOS18076.1 - 8.6e-16 57.3 0.0 4.8e-13 48.3 0.0 2.8 3 0 0 3 3 3 2 Actin SURF6 PF04935.7 KOS18077.1 - 1.5e-47 161.6 36.5 1.5e-47 161.6 25.3 5.2 3 1 1 4 4 4 1 Surfeit locus protein 6 RRP14 PF15459.1 KOS18077.1 - 5.1e-18 64.9 0.8 5.1e-18 64.9 0.6 8.7 7 2 1 8 8 8 1 60S ribosome biogenesis protein Rrp14 Peptidase_C14 PF00656.17 KOS18078.1 - 4e-73 246.1 0.0 4.9e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KOS18078.1 - 0.14 12.0 0.2 0.75 9.6 0.0 2.2 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Acetyltransf_1 PF00583.19 KOS18079.1 - 2e-09 37.3 0.0 3.4e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS18079.1 - 3.1e-08 33.6 0.0 5.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS18079.1 - 0.004 17.0 0.1 0.048 13.5 0.1 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS18079.1 - 0.008 16.2 0.0 0.018 15.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KOS18079.1 - 0.076 12.7 0.1 0.29 10.8 0.1 1.9 1 1 0 1 1 1 0 FR47-like protein YccV-like PF08755.6 KOS18080.1 - 0.00023 21.0 0.1 0.00041 20.2 0.1 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Microtub_assoc PF07989.6 KOS18081.1 - 2.3e-28 97.8 4.8 2.3e-28 97.8 3.3 13.1 10 5 4 14 14 14 1 Microtubule associated PACT_coil_coil PF10495.4 KOS18081.1 - 1.5e-10 40.8 0.5 6.1e-10 38.9 0.4 2.2 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Myosin_tail_1 PF01576.14 KOS18081.1 - 0.00062 17.6 48.6 0.00062 17.6 33.7 4.6 2 1 1 3 3 3 1 Myosin tail AAA_13 PF13166.1 KOS18081.1 - 0.0022 16.5 20.2 0.0022 16.5 14.0 6.1 2 1 4 6 6 6 4 AAA domain CENP-F_leu_zip PF10473.4 KOS18081.1 - 0.0052 16.6 12.7 0.0052 16.6 8.8 12.0 1 1 11 12 12 12 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 KOS18081.1 - 0.0061 16.2 2.1 0.0061 16.2 1.5 12.1 13 1 1 14 14 14 1 Homeobox associated leucine zipper Spc7 PF08317.6 KOS18081.1 - 0.056 12.0 170.3 0.018 13.6 10.4 9.4 1 1 6 9 9 9 0 Spc7 kinetochore protein WEMBL PF05701.6 KOS18081.1 - 1.6 7.0 188.7 0.14 10.5 26.2 4.5 2 1 1 3 3 3 0 Weak chloroplast movement under blue light IncA PF04156.9 KOS18081.1 - 4.2 6.9 214.3 0.79 9.2 10.4 11.1 1 1 9 10 10 10 0 IncA protein ATG16 PF08614.6 KOS18081.1 - 5.8 6.6 194.1 0.0089 15.8 9.2 11.5 2 2 8 11 11 11 0 Autophagy protein 16 (ATG16) I-set PF07679.11 KOS18082.1 - 0.0097 15.7 0.3 6.1 6.7 0.0 4.5 5 0 0 5 5 5 1 Immunoglobulin I-set domain DUF1918 PF08940.6 KOS18082.1 - 0.019 14.2 3.4 5.7 6.3 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF1918) Big_4 PF07532.6 KOS18082.1 - 0.059 12.8 0.2 3.3 7.2 0.0 3.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) Peptidase_C12 PF01088.16 KOS18083.1 - 9e-55 185.1 0.0 5.9e-54 182.4 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 RmuC PF02646.11 KOS18083.1 - 0.15 10.8 0.2 0.73 8.6 0.0 1.9 2 0 0 2 2 2 0 RmuC family Asp PF00026.18 KOS18085.1 - 1.1e-110 369.8 0.0 1.3e-110 369.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KOS18085.1 - 1.6e-11 44.4 0.2 3.8e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KOS18085.1 - 2.7e-07 30.9 0.1 0.0038 17.6 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KOS18085.1 - 2.4e-05 23.9 0.0 0.00013 21.5 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Alpha-amylase_C PF02806.13 KOS18085.1 - 0.057 13.5 0.1 0.22 11.6 0.0 2.0 2 1 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain DUF155 PF02582.9 KOS18087.1 - 7.7e-36 123.6 0.0 1e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 CRAL_TRIO PF00650.15 KOS18088.1 - 1.2e-35 122.3 0.0 1.7e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KOS18088.1 - 4.1e-09 36.4 0.2 4.1e-09 36.4 0.1 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KOS18088.1 - 7e-05 22.7 0.0 0.0005 20.0 0.0 2.0 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Tmemb_cc2 PF10267.4 KOS18089.1 - 1.8 7.0 8.6 1.9 6.9 6.0 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Pheromone PF08015.6 KOS18089.1 - 9 7.2 9.6 24 5.8 6.3 2.1 1 1 0 1 1 1 0 Fungal mating-type pheromone AAA PF00004.24 KOS18090.1 - 2.1e-45 154.1 0.8 1.2e-44 151.7 0.0 2.5 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS18090.1 - 4e-09 36.3 0.3 1.5e-08 34.4 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KOS18090.1 - 5.3e-08 32.9 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KOS18090.1 - 3.9e-07 30.2 0.0 1.6e-06 28.2 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 KOS18090.1 - 2.5e-06 27.6 2.3 0.00027 21.0 0.4 2.8 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 KOS18090.1 - 3.3e-06 26.2 0.0 7.1e-06 25.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KOS18090.1 - 0.00022 21.1 0.1 0.00097 19.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KOS18090.1 - 0.00026 20.7 0.6 0.056 13.0 0.0 3.5 4 0 0 4 4 4 1 NACHT domain AAA_28 PF13521.1 KOS18090.1 - 0.00051 20.0 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KOS18090.1 - 0.00055 19.0 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KOS18090.1 - 0.0011 19.7 0.0 0.0051 17.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 KOS18090.1 - 0.0011 19.0 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 KOS18090.1 - 0.0013 17.5 0.0 0.0023 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 KOS18090.1 - 0.0014 18.3 0.2 0.0037 16.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 KOS18090.1 - 0.0022 17.6 0.0 0.0074 16.0 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_23 PF13476.1 KOS18090.1 - 0.003 17.9 1.9 0.84 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KOS18090.1 - 0.004 16.2 0.1 0.012 14.7 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.1 KOS18090.1 - 0.0042 16.6 0.8 0.016 14.8 0.0 2.2 2 1 1 3 3 3 1 AAA domain AAA_3 PF07726.6 KOS18090.1 - 0.0044 16.6 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_Hsp90 PF03225.9 KOS18090.1 - 0.0051 15.1 0.0 0.0081 14.4 0.0 1.2 1 0 0 1 1 1 1 Viral heat shock protein Hsp90 homologue AAA_33 PF13671.1 KOS18090.1 - 0.0052 16.6 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KOS18090.1 - 0.0055 16.4 0.8 0.052 13.2 0.0 2.6 2 1 1 3 3 3 1 Archaeal ATPase UPF0079 PF02367.12 KOS18090.1 - 0.0056 16.2 0.0 0.046 13.3 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 KOS18090.1 - 0.0069 15.5 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KOS18090.1 - 0.01 15.4 0.1 0.031 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KOS18090.1 - 0.013 14.9 0.3 0.03 13.7 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 KOS18090.1 - 0.013 15.1 0.2 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KOS18090.1 - 0.017 14.5 2.7 0.081 12.3 0.1 2.7 2 1 1 3 3 3 0 AAA domain KaiC PF06745.8 KOS18090.1 - 0.024 13.7 1.2 0.47 9.5 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.1 KOS18090.1 - 0.027 14.7 0.1 0.11 12.8 0.0 2.1 2 1 0 2 2 1 0 AAA domain Bac_DnaA PF00308.13 KOS18090.1 - 0.032 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.21 KOS18090.1 - 0.051 13.0 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Cast PF10174.4 KOS18090.1 - 0.052 11.5 2.8 0.058 11.4 1.2 1.5 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone AFG1_ATPase PF03969.11 KOS18090.1 - 0.058 12.1 0.1 0.14 10.9 0.0 1.6 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activ_2 PF14532.1 KOS18090.1 - 0.095 12.7 0.2 0.41 10.6 0.0 2.2 2 1 0 2 2 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KOS18090.1 - 0.17 10.7 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Folliculin PF11704.3 KOS18091.1 - 4.3e-27 94.7 0.0 7.4e-26 90.7 0.0 2.6 2 1 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport Drc1-Sld2 PF11719.3 KOS18092.1 - 5e-88 296.0 30.7 1.4e-87 294.6 17.0 2.5 1 1 1 2 2 2 1 DNA replication and checkpoint protein TFIIA PF03153.8 KOS18092.1 - 0.0041 17.0 9.9 0.0041 17.0 6.9 2.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit alpha-hel2 PF14456.1 KOS18092.1 - 2.3 6.9 8.6 4.3 6.0 6.0 1.4 1 0 0 1 1 1 0 Alpha-helical domain 2 JSRP PF15312.1 KOS18092.1 - 5 7.1 5.5 2.3 8.2 0.1 2.7 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Nrap PF03813.9 KOS18093.1 - 0 1020.0 0.0 0 1019.8 0.0 1.0 1 0 0 1 1 1 1 Nrap protein DNA_methylase PF00145.12 KOS18095.1 - 3.2e-38 131.7 0.0 1.1e-26 93.8 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Mu-like_Pro PF10123.4 KOS18096.1 - 0.0018 17.7 0.5 0.0037 16.7 0.3 1.4 1 0 0 1 1 1 1 Mu-like prophage I protein SEN1_N PF12726.2 KOS18097.1 - 2e-123 413.0 0.0 3.3e-123 412.2 0.0 1.3 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 KOS18097.1 - 3.3e-70 236.3 0.6 3.3e-70 236.3 0.4 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KOS18097.1 - 3.1e-62 209.5 0.0 6.1e-62 208.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS18097.1 - 5e-11 42.1 1.6 1.5e-10 40.6 0.3 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KOS18097.1 - 2.9e-08 33.5 3.0 7.8e-05 22.3 0.1 3.9 3 0 0 3 3 3 2 AAA domain UvrD-helicase PF00580.16 KOS18097.1 - 1.8e-06 27.5 4.1 8.7e-05 21.9 0.0 3.5 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 KOS18097.1 - 6.3e-05 22.5 0.1 0.16 11.4 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KOS18097.1 - 0.0062 15.9 0.2 0.017 14.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KOS18097.1 - 0.019 15.0 0.2 0.91 9.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF936 PF06075.7 KOS18098.1 - 2.1 7.1 38.7 2.6 6.8 26.8 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Serglycin PF04360.7 KOS18099.1 - 0.72 9.5 3.9 0.33 10.6 1.1 1.7 2 0 0 2 2 2 0 Serglycin CPSase_L_D2 PF02786.12 KOS18100.1 - 5e-112 372.3 0.2 1e-83 279.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 KOS18100.1 - 4e-45 153.6 0.0 9.1e-45 152.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 KOS18100.1 - 4.5e-45 152.3 0.0 1.3e-44 150.8 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 KOS18100.1 - 1.1e-42 145.0 0.0 2.2e-42 144.0 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 KOS18100.1 - 6.9e-42 142.0 0.0 7.9e-21 74.2 0.0 2.9 3 0 0 3 3 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 KOS18100.1 - 2e-41 140.5 0.2 1.8e-40 137.5 0.0 2.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KOS18100.1 - 8.3e-36 123.4 0.2 1.1e-22 80.7 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 KOS18100.1 - 7.9e-32 110.3 0.0 1.9e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 KOS18100.1 - 1.5e-23 83.0 0.0 2.2e-12 46.3 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 KOS18100.1 - 2.7e-22 78.5 0.0 2.1e-21 75.6 0.0 2.7 3 0 0 3 3 2 1 MGS-like domain ATP-grasp PF02222.17 KOS18100.1 - 1.7e-16 60.0 0.1 3.3e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KOS18100.1 - 7.3e-16 58.1 0.6 1.3e-07 31.2 0.1 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.8 KOS18100.1 - 1.1e-06 28.2 0.2 5.3e-05 22.7 0.1 2.8 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.6 KOS18100.1 - 1.4e-06 27.9 0.1 0.00067 19.1 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KOS18100.1 - 3.1e-06 27.1 0.4 0.044 13.6 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KOS18100.1 - 0.00097 18.7 0.4 2.3 7.7 0.0 3.0 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.19 KOS18100.1 - 0.057 12.8 0.1 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Cyclin_N PF00134.18 KOS18102.1 - 3.4e-05 23.3 0.0 0.0014 18.1 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain PNPOx_C PF10590.4 KOS18103.1 - 1.3e-18 66.2 2.8 4e-18 64.6 2.0 1.9 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 KOS18103.1 - 3.5e-18 65.4 0.0 5.6e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 KOS18103.1 - 0.0044 17.3 0.0 0.031 14.5 0.0 2.1 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase adh_short PF00106.20 KOS18104.1 - 1e-60 204.4 7.7 5.7e-30 104.4 0.6 2.4 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 KOS18104.1 - 2.1e-30 104.6 0.0 5.9e-30 103.1 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain KR PF08659.5 KOS18104.1 - 1.2e-26 93.4 1.9 1.3e-12 47.7 0.1 2.6 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KOS18104.1 - 1.8e-19 70.4 0.5 8.9e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 KOS18104.1 - 1.8e-10 40.7 0.2 3.1e-06 27.0 0.0 2.8 3 0 0 3 3 3 2 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 KOS18104.1 - 5.5e-05 22.2 0.4 0.3 10.1 0.1 2.6 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4161 PF13722.1 KOS18104.1 - 0.011 15.9 0.7 0.94 9.7 0.0 2.5 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) Epimerase PF01370.16 KOS18104.1 - 0.036 13.4 2.8 0.11 11.9 0.1 2.5 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KOS18104.1 - 0.13 11.8 7.2 3.3 7.3 0.5 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ArgK PF03308.11 KOS18105.1 - 1.6e-05 23.8 0.0 2.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 ArgK protein SRP54 PF00448.17 KOS18105.1 - 3.9e-05 23.1 0.0 5.4e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 KOS18105.1 - 5.8e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KOS18105.1 - 0.0002 22.1 0.0 0.00076 20.2 0.0 2.0 1 1 1 2 2 2 1 AAA domain HD_assoc PF13286.1 KOS18105.1 - 0.0049 17.1 0.0 0.031 14.5 0.0 2.1 2 0 0 2 2 2 1 Phosphohydrolase-associated domain CbiA PF01656.18 KOS18105.1 - 0.0065 15.8 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain KAP_NTPase PF07693.9 KOS18105.1 - 0.0082 15.1 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_19 PF13245.1 KOS18105.1 - 0.028 14.1 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KOS18105.1 - 0.036 14.3 0.0 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KOS18105.1 - 0.051 13.2 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 KOS18105.1 - 0.054 13.2 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 NTPase Thymidylate_kin PF02223.12 KOS18105.1 - 0.07 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase MobB PF03205.9 KOS18105.1 - 0.073 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KOS18105.1 - 0.081 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 KOS18105.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Torsin Cation_efflux PF01545.16 KOS18106.1 - 4.6e-28 98.0 11.0 5.8e-28 97.7 7.6 1.0 1 0 0 1 1 1 1 Cation efflux family Enamelin PF15362.1 KOS18107.1 - 5.9 4.8 5.3 7.4 4.5 3.7 1.1 1 0 0 1 1 1 0 Enamelin PIG-Y PF15159.1 KOS18107.1 - 6.3 7.0 8.8 22 5.3 6.1 1.9 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Spb1_C PF07780.7 KOS18108.1 - 8.9e-74 247.6 16.4 8.9e-74 247.6 11.4 4.5 3 2 1 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.3 KOS18108.1 - 2.1e-57 193.1 4.8 2.1e-57 193.1 3.3 4.6 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 KOS18108.1 - 1.5e-47 161.8 0.0 3.2e-47 160.8 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF2956 PF11169.3 KOS18108.1 - 0.0049 16.8 3.0 0.0049 16.8 2.1 5.0 3 2 2 5 5 5 1 Protein of unknown function (DUF2956) Dynamin_N PF00350.18 KOS18109.1 - 2.7e-43 147.6 0.0 5e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KOS18109.1 - 4.8e-10 38.6 0.0 5.1e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KOS18109.1 - 0.00066 19.6 0.0 0.0047 16.8 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KOS18109.1 - 0.0016 18.8 0.1 0.0065 16.9 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 KOS18109.1 - 0.018 15.0 0.4 0.25 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain SRI PF08236.6 KOS18109.1 - 0.09 12.7 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain AAA_21 PF13304.1 KOS18109.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain STAT_int PF02865.12 KOS18109.1 - 1.8 8.5 4.2 1.9 8.4 0.1 3.0 4 0 0 4 4 4 0 STAT protein, protein interaction domain Sterol-sensing PF12349.3 KOS18110.1 - 3.6e-26 91.4 10.0 6.7e-26 90.5 6.9 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KOS18110.1 - 3.9e-07 28.4 5.4 5.6e-07 27.8 3.7 1.1 1 0 0 1 1 1 1 Patched family Cupin_8 PF13621.1 KOS18111.1 - 2.5e-51 174.6 0.0 3e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KOS18111.1 - 0.0039 16.4 0.1 0.054 12.7 0.1 2.2 2 0 0 2 2 2 1 Cupin superfamily protein GFO_IDH_MocA PF01408.17 KOS18113.1 - 2.3e-20 73.2 0.0 4.2e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 KOS18113.1 - 0.00015 22.0 0.0 0.00065 19.9 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain PCP_red PF08369.5 KOS18113.1 - 0.045 13.6 0.3 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit GFO_IDH_MocA_C PF02894.12 KOS18113.1 - 0.068 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain AMP-binding PF00501.23 KOS18114.1 - 6.4e-82 275.1 0.0 2.5e-81 273.1 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KOS18114.1 - 8.8e-76 254.7 0.9 2e-75 253.5 0.6 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KOS18114.1 - 1.9e-52 177.5 4.6 4.6e-52 176.2 0.1 3.6 4 0 0 4 4 3 1 KR domain adh_short PF00106.20 KOS18114.1 - 7.3e-46 156.1 4.2 2.7e-43 147.7 0.0 4.3 4 0 0 4 4 4 1 short chain dehydrogenase PS-DH PF14765.1 KOS18114.1 - 4.7e-44 150.7 0.6 2.7e-42 144.9 0.0 2.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KOS18114.1 - 8.3e-44 150.2 0.2 1.8e-43 149.0 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain Condensation PF00668.15 KOS18114.1 - 1.2e-39 135.9 0.1 3.1e-37 128.0 0.0 2.4 1 1 1 2 2 2 1 Condensation domain NAD_binding_4 PF07993.7 KOS18114.1 - 4e-28 98.0 0.0 2.3e-27 95.5 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KOS18114.1 - 4e-28 97.6 0.1 1.6e-27 95.6 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KOS18114.1 - 5.7e-20 71.3 0.0 3.5e-09 36.8 0.0 3.1 3 0 0 3 3 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KOS18114.1 - 9.4e-14 51.6 0.0 3.7e-13 49.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS18114.1 - 2.1e-11 43.6 0.0 4.9e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 KOS18114.1 - 5e-11 42.7 0.1 2.2e-10 40.7 0.1 2.1 2 0 0 2 2 1 1 HxxPF-repeated domain Methyltransf_11 PF08241.7 KOS18114.1 - 1.3e-10 41.5 0.0 7.9e-10 39.0 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS18114.1 - 1.9e-10 41.3 0.0 1.2e-08 35.5 0.0 3.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS18114.1 - 7.2e-10 38.8 0.0 1.7e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KOS18114.1 - 3.3e-08 33.2 0.0 4.5e-06 26.2 0.0 2.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.18 KOS18114.1 - 5.4e-05 22.3 0.0 0.00012 21.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KOS18114.1 - 0.00018 20.6 0.0 0.00048 19.3 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.14 KOS18114.1 - 0.0043 15.7 0.0 0.74 8.4 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NodS PF05401.6 KOS18114.1 - 0.0047 16.3 0.0 0.0098 15.3 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.7 KOS18114.1 - 0.094 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase NNMT_PNMT_TEMT PF01234.12 KOS18114.1 - 0.14 11.0 0.0 0.3 10.0 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_16 PF10294.4 KOS18114.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CheR PF01739.13 KOS18114.1 - 0.21 10.8 0.0 0.69 9.1 0.0 1.7 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain PCMT PF01135.14 KOS18114.1 - 0.28 10.6 0.0 3.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HPS3_C PF14763.1 KOS18114.1 - 0.36 9.7 0.0 3.8 6.3 0.0 2.1 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3, C-terminal RrnaAD PF00398.15 KOS18114.1 - 0.66 8.9 0.0 1.4 7.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Sporozoite_P67 PF05642.6 KOS18114.1 - 4.5 5.0 1.5 7.1 4.3 1.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GMC_oxred_N PF00732.14 KOS18115.1 - 5.4e-54 183.3 0.0 7.8e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KOS18115.1 - 9.8e-26 90.7 0.1 1.7e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KOS18115.1 - 0.00022 20.2 0.1 0.00035 19.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KOS18115.1 - 0.0023 17.9 6.3 0.0047 16.9 0.0 3.6 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KOS18115.1 - 0.042 13.6 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.11 KOS18116.1 - 1e-38 132.9 41.6 1e-38 132.9 28.8 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KOS18116.1 - 4.3e-08 31.8 11.4 6.9e-08 31.1 7.9 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 KOS18116.1 - 0.023 14.6 0.5 0.81 9.6 0.2 2.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 PolC_DP2 PF03833.8 KOS18116.1 - 0.077 10.6 0.1 0.11 10.1 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 RRM_1 PF00076.17 KOS18118.1 - 9.8e-20 69.9 0.0 5.4e-14 51.5 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS18118.1 - 1e-09 38.1 0.0 6e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS18118.1 - 0.0098 15.7 0.1 0.52 10.2 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LicD PF04991.8 KOS18119.1 - 1.8e-32 113.1 1.6 5.7e-31 108.2 1.1 2.2 1 1 0 1 1 1 1 LicD family bZIP_C PF12498.3 KOS18119.1 - 0.4 11.9 3.2 11 7.3 0.1 2.3 2 0 0 2 2 2 0 Basic leucine-zipper C terminal DUF1289 PF06945.8 KOS18119.1 - 0.69 9.4 2.8 1.2 8.6 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) DUF4231 PF14015.1 KOS18120.1 - 0.16 11.9 0.3 0.25 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Ecl1 PF12855.2 KOS18121.1 - 0.27 10.5 6.7 1.9 7.8 0.4 2.7 2 0 0 2 2 2 0 Life-span regulatory factor zf-MYND PF01753.13 KOS18121.1 - 1.1 9.1 22.0 0.58 10.0 3.1 3.5 3 0 0 3 3 3 0 MYND finger Striatin PF08232.7 KOS18122.1 - 3.5e-34 118.0 0.4 3.5e-34 118.0 0.2 2.5 2 0 0 2 2 2 1 Striatin family WD40 PF00400.27 KOS18122.1 - 2.4e-31 106.4 15.1 3e-07 30.0 0.1 7.0 6 1 0 6 6 6 5 WD domain, G-beta repeat PAT1 PF09770.4 KOS18122.1 - 4.2 5.4 38.1 6 4.9 26.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 P5CR_dimer PF14748.1 KOS18123.1 - 3e-31 107.5 1.3 5.5e-31 106.7 0.9 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KOS18123.1 - 4.3e-11 43.1 1.3 1.7e-09 38.0 0.0 2.6 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent zf-C2H2_jaz PF12171.3 KOS18124.1 - 0.00024 21.1 2.5 0.014 15.5 0.0 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS18124.1 - 0.0014 18.7 1.0 0.13 12.5 0.3 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KOS18124.1 - 0.0033 17.6 0.9 0.0033 17.6 0.6 5.1 6 0 0 6 6 6 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KOS18124.1 - 0.014 15.2 0.1 0.054 13.4 0.1 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KOS18124.1 - 3.2 7.9 10.9 2.1 8.5 0.7 3.4 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Actin PF00022.14 KOS18125.1 - 2.1e-42 144.9 0.0 5.1e-23 81.1 0.0 2.9 2 1 0 2 2 2 2 Actin Peptidase_M28 PF04389.12 KOS18126.1 - 5.7e-35 120.6 0.0 1.3e-34 119.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KOS18126.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KOS18126.1 - 0.043 12.5 0.0 0.07 11.8 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase DUF2305 PF10230.4 KOS18127.1 - 4.8e-54 183.5 0.0 5.6e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KOS18127.1 - 2.6e-06 27.5 0.1 3.7e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS18127.1 - 7.5e-06 25.7 0.0 1.8e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KOS18127.1 - 0.0092 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Acyltransferase PF01553.16 KOS18128.1 - 3.5e-25 87.9 0.0 4.8e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase NAD_kinase PF01513.16 KOS18129.1 - 5.4e-41 140.2 0.0 1.7e-40 138.5 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase Gas_vesicle_C PF01304.12 KOS18129.1 - 0.31 10.6 2.7 0.47 10.1 0.4 2.0 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain GFO_IDH_MocA PF01408.17 KOS18130.1 - 8.9e-23 81.0 0.1 1.4e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KOS18130.1 - 6.7e-10 38.7 0.0 1.4e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KOS18130.1 - 0.051 13.9 0.1 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain PLA2_B PF01735.13 KOS18131.1 - 7.6e-174 578.4 0.2 8.9e-174 578.2 0.1 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Amidase PF01425.16 KOS18132.1 - 9e-66 222.5 0.7 5.1e-65 220.0 0.5 1.8 1 1 0 1 1 1 1 Amidase CFEM PF05730.6 KOS18133.1 - 2e-11 43.5 11.3 3.4e-11 42.8 7.8 1.4 1 0 0 1 1 1 1 CFEM domain CDC27 PF09507.5 KOS18133.1 - 1 8.5 4.6 1.2 8.2 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 VID27 PF08553.5 KOS18135.1 - 0 1065.1 0.7 0 1062.4 0.5 1.9 1 1 0 1 1 1 1 VID27 cytoplasmic protein Spore_coat_CotO PF14153.1 KOS18135.1 - 0.021 14.2 10.0 0.15 11.4 1.3 2.4 2 0 0 2 2 2 0 Spore coat protein CotO Daxx PF03344.10 KOS18135.1 - 7.8 4.8 24.1 0.91 7.9 4.7 2.2 2 0 0 2 2 2 0 Daxx Family ECH PF00378.15 KOS18136.1 - 6.6e-46 156.4 0.7 3.8e-42 144.1 0.3 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family DnaJ PF00226.26 KOS18137.1 - 3.4e-11 42.6 0.9 5.9e-11 41.9 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 KOS18138.1 - 1.7e-08 33.7 0.0 0.0012 18.1 0.0 2.8 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH PF00443.24 KOS18139.1 - 1.3e-26 93.3 0.0 1.7e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS18139.1 - 3.3e-10 39.8 0.0 7.1e-10 38.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PLA1 PF02253.10 KOS18140.1 - 0.06 12.7 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 Phospholipase A1 Pkinase PF00069.20 KOS18141.1 - 1.2e-74 250.7 0.0 1.6e-74 250.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS18141.1 - 9.5e-32 110.0 0.0 1.3e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS18141.1 - 0.00057 18.9 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KOS18141.1 - 0.0024 16.9 0.1 0.0042 16.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KOS18141.1 - 0.0096 15.6 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KOS18141.1 - 0.06 12.1 0.0 0.093 11.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.6 KOS18141.1 - 0.079 12.9 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.14 KOS18141.1 - 0.11 11.8 0.3 0.4 10.0 0.2 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Sec23_trunk PF04811.10 KOS18142.1 - 1.1e-70 237.8 0.0 1.7e-70 237.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KOS18142.1 - 3.5e-24 84.1 0.0 8.4e-23 79.7 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KOS18142.1 - 6.8e-18 64.9 0.0 1.4e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KOS18142.1 - 3e-17 61.8 4.7 5.1e-17 61.1 3.3 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KOS18142.1 - 6.9e-09 35.2 0.8 1.7e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat PAT1 PF09770.4 KOS18142.1 - 6.7 4.8 48.0 9.7 4.2 33.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HEM4 PF02602.10 KOS18143.1 - 1.6e-31 109.3 0.0 2.2e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TLD PF07534.11 KOS18144.1 - 2.1e-25 89.3 0.0 2.4e-14 53.5 0.0 2.1 2 0 0 2 2 2 2 TLD IBN_N PF03810.14 KOS18145.1 - 5.1e-06 26.3 0.9 0.00017 21.3 0.0 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KOS18145.1 - 8e-06 25.8 1.9 0.00019 21.3 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.1 KOS18145.1 - 0.01 16.0 0.1 0.32 11.3 0.0 3.2 4 0 0 4 4 4 0 HEAT repeats WD40 PF00400.27 KOS18146.1 - 0.015 15.2 2.4 5.2 7.1 0.0 4.8 6 0 0 6 6 6 0 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 KOS18148.1 - 1.6e-08 33.5 0.5 4e-08 32.2 0.4 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain SHOCT PF09851.4 KOS18148.1 - 0.013 14.9 0.1 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 Short C-terminal domain DUF1917 PF08939.5 KOS18149.1 - 3.8e-56 190.5 0.1 6.4e-56 189.8 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) Acetyltransf_1 PF00583.19 KOS18150.1 - 2.4e-17 62.7 0.0 3.5e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS18150.1 - 9e-10 38.5 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KOS18150.1 - 2.2e-09 36.9 0.0 3.4e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KOS18150.1 - 3.9e-09 36.7 0.0 4.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS18150.1 - 8.2e-09 35.6 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KOS18150.1 - 4e-07 30.0 0.0 4.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS18150.1 - 0.00039 20.2 0.0 0.00063 19.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KOS18150.1 - 0.022 14.6 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KOS18150.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase LpxC PF03331.8 KOS18150.1 - 0.14 11.0 0.1 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase MRP-S25 PF13741.1 KOS18152.1 - 5.9e-70 235.3 4.7 3.9e-68 229.3 3.3 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 FAD_binding_4 PF01565.18 KOS18153.1 - 4e-18 65.2 4.8 1.1e-17 63.7 3.1 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KOS18153.1 - 3.1e-11 42.9 0.2 5.7e-11 42.1 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KOS18153.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.18 KOS18154.1 - 1.6e-17 63.3 1.1 3.7e-17 62.0 0.7 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KOS18154.1 - 2.4e-07 30.5 0.2 4.6e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like TGF_beta_GS PF08515.7 KOS18155.1 - 0.2 10.9 2.9 0.38 10.1 2.0 1.4 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Abhydrolase_6 PF12697.2 KOS18156.1 - 3.2e-31 108.9 5.2 5.2e-31 108.2 3.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS18156.1 - 8.5e-13 48.2 0.0 2.3e-12 46.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS18156.1 - 0.00088 18.8 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold IRS PF02174.12 KOS18156.1 - 0.027 14.0 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 PTB domain (IRS-1 type) TPP_enzyme_N PF02776.13 KOS18156.1 - 0.055 12.9 0.1 0.85 9.0 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Alg14 PF08660.6 KOS18157.1 - 1.3e-36 126.1 0.0 1.5e-34 119.4 0.0 2.1 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Aldo_ket_red PF00248.16 KOS18158.1 - 3.5e-46 157.3 0.0 4e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_3 PF01494.14 KOS18159.1 - 9.8e-20 70.8 1.0 3.4e-12 46.1 0.1 2.7 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KOS18159.1 - 1.2e-06 28.4 0.2 4e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KOS18159.1 - 4.4e-06 25.8 1.2 0.027 13.3 0.0 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KOS18159.1 - 4.1e-05 23.8 0.3 0.00013 22.2 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KOS18159.1 - 0.0016 18.5 0.4 0.029 14.4 0.1 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KOS18159.1 - 0.0017 17.2 0.4 0.0076 15.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KOS18159.1 - 0.0051 15.7 1.3 0.097 11.5 0.4 2.2 1 1 1 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 KOS18159.1 - 0.024 13.7 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.19 KOS18159.1 - 0.024 13.7 0.7 0.17 10.9 0.0 2.2 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 KOS18159.1 - 0.045 12.3 0.2 1.5 7.3 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 KOS18159.1 - 0.05 13.4 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS18159.1 - 0.09 12.5 2.3 2.6 7.7 0.1 2.4 1 1 1 2 2 2 0 FAD-NAD(P)-binding DIOX_N PF14226.1 KOS18160.1 - 6.9e-24 84.6 0.0 1.1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KOS18160.1 - 5.3e-16 58.7 0.0 1.1e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RhoGAP PF00620.22 KOS18161.1 - 1.9e-47 160.6 0.1 5.9e-47 159.0 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KOS18161.1 - 3.7e-12 46.2 1.2 6.8e-12 45.4 0.1 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DnaI_N PF07319.6 KOS18161.1 - 0.08 13.1 1.1 1.3 9.3 0.1 2.7 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus DUF4407 PF14362.1 KOS18161.1 - 0.26 10.2 7.4 0.46 9.4 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 KOS18161.1 - 0.52 9.8 6.2 0.24 10.9 2.3 1.9 1 1 0 1 1 1 0 IncA protein Med12 PF09497.5 KOS18162.1 - 1.9e-27 95.0 0.2 5.8e-27 93.4 0.2 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 KOS18162.1 - 0.0025 16.3 0.3 1.2 7.5 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic Mediator 12 subunit domain Pyrid_oxidase_2 PF13883.1 KOS18163.1 - 6.1e-39 133.5 0.0 3.6e-38 130.9 0.0 2.1 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.20 KOS18164.1 - 1.1e-57 195.1 0.0 7.7e-57 192.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS18164.1 - 1.1e-28 100.0 0.3 2.4e-20 72.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KOS18164.1 - 4.1e-07 30.4 0.2 1.3e-06 28.8 0.2 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KOS18164.1 - 0.0004 19.4 0.3 0.0022 17.0 0.0 2.1 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 KOS18164.1 - 0.014 15.1 1.9 0.14 11.8 0.8 3.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF1752 PF08550.5 KOS18165.1 - 7.6e-10 38.1 0.4 1.5e-09 37.2 0.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Bd3614_N PF14442.1 KOS18165.1 - 0.25 11.3 12.8 0.54 10.2 8.9 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal RXT2_N PF08595.6 KOS18165.1 - 4.2 7.1 9.3 7.7 6.3 6.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 KOS18165.1 - 7.2 5.7 13.2 12 5.0 9.2 1.3 1 0 0 1 1 1 0 NOA36 protein Wbp11 PF09429.5 KOS18166.1 - 1.1e-22 79.8 13.3 1.1e-22 79.8 9.2 2.5 3 0 0 3 3 3 1 WW domain binding protein 11 Sigma70_ner PF04546.8 KOS18166.1 - 2.7 7.5 14.7 0.13 11.8 2.9 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region MFS_1 PF07690.11 KOS18167.1 - 1.1e-36 126.3 72.8 1e-34 119.8 32.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS18167.1 - 5.3e-06 25.2 10.3 5.3e-06 25.2 7.1 3.2 2 2 1 3 3 3 3 Sugar (and other) transporter DFP PF04127.10 KOS18168.1 - 1.5e-11 44.2 0.0 7.4e-06 25.7 0.0 3.1 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.13 KOS18168.1 - 0.15 11.7 0.0 15 5.1 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acatn PF13000.2 KOS18169.1 - 9.2e-144 479.9 18.7 7.1e-77 259.1 5.6 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Serglycin PF04360.7 KOS18169.1 - 0.024 14.3 13.5 0.1 12.3 9.4 1.9 1 1 0 1 1 1 0 Serglycin CENP-O PF09496.5 KOS18170.1 - 7.2e-20 71.0 0.0 1.3e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Macoilin PF09726.4 KOS18170.1 - 0.3 9.3 18.3 0.44 8.7 12.7 1.2 1 0 0 1 1 1 0 Transmembrane protein Striatin PF08232.7 KOS18170.1 - 0.32 11.3 1.7 0.55 10.5 1.2 1.3 1 0 0 1 1 1 0 Striatin family Pex14_N PF04695.8 KOS18170.1 - 2.4 8.2 12.0 5.3 7.1 8.3 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lzipper-MIP1 PF14389.1 KOS18170.1 - 2.4 8.3 5.1 7.7 6.6 0.0 2.8 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Lin-8 PF03353.10 KOS18170.1 - 3.4 6.8 7.3 5.3 6.2 5.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4482 PF14818.1 KOS18170.1 - 4.1 8.0 7.4 6.3 7.4 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) DUF572 PF04502.8 KOS18170.1 - 8.9 5.4 8.8 13 4.8 6.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF566 PF04484.7 KOS18170.1 - 9.6 5.6 23.9 15 4.9 16.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF702 PF05142.7 KOS18170.1 - 9.8 6.3 7.9 17 5.5 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF2962 PF11176.3 KOS18171.1 - 2.4e-44 150.6 0.1 2.8e-44 150.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) FliD_C PF07195.7 KOS18171.1 - 0.055 12.7 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Dehydratase_LU PF02286.10 KOS18171.1 - 0.14 10.3 0.1 0.16 10.1 0.1 1.0 1 0 0 1 1 1 0 Dehydratase large subunit XPG_N PF00752.12 KOS18172.1 - 6.9e-25 87.2 0.0 1.2e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KOS18172.1 - 1.8e-24 85.5 0.0 3.5e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 KOS18172.1 - 0.00043 19.8 0.0 0.00079 18.9 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.12 KOS18172.1 - 0.004 16.9 0.0 0.0096 15.7 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KOS18172.1 - 0.0067 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 TPR repeat 5_3_exonuc PF01367.15 KOS18172.1 - 0.059 13.6 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TPR_1 PF00515.23 KOS18172.1 - 0.061 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 KOS18172.1 - 0.062 13.9 0.1 0.27 11.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Oxysterol_BP PF01237.13 KOS18173.1 - 4.7e-54 183.2 0.0 2.2e-43 148.1 0.0 2.3 2 1 0 2 2 2 2 Oxysterol-binding protein MAM33 PF02330.11 KOS18174.1 - 1.8e-34 119.3 2.7 2.3e-34 118.9 1.9 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein PUF PF00806.14 KOS18175.1 - 2.5e-08 32.9 0.0 0.39 10.3 0.0 5.5 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat Nucleoplasmin PF03066.10 KOS18175.1 - 0.0064 16.0 6.7 0.0064 16.0 4.6 3.8 3 1 0 3 3 3 1 Nucleoplasmin AMMECR1 PF01871.12 KOS18177.1 - 3.9e-42 143.2 0.0 7e-42 142.4 0.0 1.3 1 0 0 1 1 1 1 AMMECR1 ORC6 PF05460.8 KOS18177.1 - 0.18 10.8 4.7 0.23 10.4 3.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ras PF00071.17 KOS18178.1 - 1.1e-38 132.2 0.0 1.1e-24 86.5 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KOS18178.1 - 6.4e-12 46.0 0.0 1.1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS18178.1 - 0.0012 18.1 0.0 0.012 14.9 0.0 2.0 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KOS18178.1 - 0.0047 16.8 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase T_hemolysin PF12261.3 KOS18178.1 - 0.028 13.9 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Thermostable hemolysin Cleaved_Adhesin PF07675.6 KOS18178.1 - 0.051 13.1 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Cleaved Adhesin Domain GTP_EFTU PF00009.22 KOS18178.1 - 0.052 12.9 0.0 1.3 8.4 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PRK PF00485.13 KOS18178.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family FHA PF00498.21 KOS18179.1 - 6.5e-15 54.9 0.0 1.1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain DUF4106 PF13388.1 KOS18179.1 - 0.15 10.9 0.5 0.2 10.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) TEX13 PF15186.1 KOS18180.1 - 0.17 11.4 0.1 0.17 11.4 0.1 1.8 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Thioesterase PF00975.15 KOS18181.1 - 2.7e-12 47.3 0.1 4.9e-09 36.7 0.1 2.9 2 1 0 2 2 2 2 Thioesterase domain Abhydrolase_6 PF12697.2 KOS18181.1 - 0.00087 19.2 6.6 0.0014 18.5 4.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS18181.1 - 0.009 15.7 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Couple_hipA PF13657.1 KOS18183.1 - 0.041 14.1 0.2 1.7 8.9 0.0 2.5 1 1 1 2 2 2 0 HipA N-terminal domain adh_short PF00106.20 KOS18184.1 - 2.4e-28 99.1 1.8 2.9e-28 98.8 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS18184.1 - 2.7e-28 99.3 0.1 3.1e-28 99.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS18184.1 - 5.4e-16 58.7 0.5 7.2e-16 58.3 0.3 1.1 1 0 0 1 1 1 1 KR domain OPT PF03169.10 KOS18185.1 - 1.2e-82 278.3 41.8 1.5e-82 278.0 29.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Kinesin PF00225.18 KOS18186.1 - 3.1e-115 384.4 0.6 4.2e-115 384.0 0.4 1.2 1 0 0 1 1 1 1 Kinesin motor domain AAA_33 PF13671.1 KOS18186.1 - 0.00057 19.7 1.5 0.013 15.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain DinB_2 PF12867.2 KOS18186.1 - 0.14 12.5 0.8 0.65 10.3 0.1 2.4 1 1 1 2 2 2 0 DinB superfamily zf-C2H2 PF00096.21 KOS18187.1 - 1.4e-05 25.1 3.0 0.08 13.3 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS18187.1 - 0.00062 19.9 2.1 0.098 13.0 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KOS18187.1 - 0.06 13.4 1.0 3.3 7.8 0.6 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KOS18187.1 - 0.099 12.8 4.5 2.5 8.3 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KOS18187.1 - 0.15 11.9 3.0 3.7 7.5 0.0 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger Shadoo PF14999.1 KOS18187.1 - 0.29 10.9 4.9 0.98 9.2 0.3 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective K_channel_TID PF07941.6 KOS18187.1 - 1.4 9.2 7.4 1.8 8.8 0.1 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Fungal_trans PF04082.13 KOS18189.1 - 2.8e-12 46.0 0.2 5.1e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SR-25 PF10500.4 KOS18189.1 - 0.0098 15.3 4.9 0.019 14.4 3.4 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Tim17 PF02466.14 KOS18190.1 - 0.11 12.5 3.8 0.19 11.7 2.6 1.4 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family CGI-121 PF08617.5 KOS18192.1 - 1.1e-45 155.2 0.1 1.2e-45 155.0 0.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Pro_dh PF01619.13 KOS18193.1 - 3e-39 134.8 0.0 4.8e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Cas_Csy1 PF09611.5 KOS18193.1 - 0.036 12.9 0.0 0.074 11.9 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) DUF3362 PF11842.3 KOS18194.1 - 0.087 12.7 0.1 1.6 8.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3362) WH1 PF00568.18 KOS18196.1 - 1.7e-28 98.5 0.9 2.6e-28 97.9 0.6 1.3 1 0 0 1 1 1 1 WH1 domain eIF-1a PF01176.14 KOS18197.1 - 9.3e-27 92.2 0.1 1.3e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PTCB-BRCT PF12738.2 KOS18198.1 - 2.6e-10 39.9 0.0 5.2e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KOS18198.1 - 2e-09 37.4 0.0 3.6e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 KOS18198.1 - 0.00073 19.2 1.9 0.0039 16.9 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3006) fn3 PF00041.16 KOS18198.1 - 0.01 15.9 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 Fibronectin type III domain NOA36 PF06524.7 KOS18198.1 - 6.5 5.9 10.2 10 5.2 7.0 1.3 1 0 0 1 1 1 0 NOA36 protein adh_short PF00106.20 KOS18199.1 - 2.5e-10 40.5 0.2 1.6e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KOS18199.1 - 2.9e-05 23.8 0.0 5.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KOS18199.1 - 0.036 13.8 0.0 0.092 12.4 0.0 1.5 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Gag_spuma PF03276.9 KOS18200.1 - 2.4 6.3 7.4 3.4 5.8 5.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein CDP-OH_P_transf PF01066.16 KOS18201.1 - 1.1e-13 51.3 4.3 1.8e-13 50.6 3.0 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase F-box-like PF12937.2 KOS18203.1 - 1.7e-09 37.2 0.1 1.4e-07 31.1 0.0 3.0 2 1 1 3 3 3 2 F-box-like F-box PF00646.28 KOS18203.1 - 5.3e-06 25.9 0.2 4e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 F-box domain Ribosomal_L24e PF01246.15 KOS18204.1 - 9.5e-32 108.6 0.4 9.5e-32 108.6 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e SSB PF00436.20 KOS18204.1 - 0.62 9.9 2.5 2.9 7.7 0.7 2.0 2 0 0 2 2 2 0 Single-strand binding protein family Redoxin PF08534.5 KOS18205.1 - 1.6e-35 121.8 0.3 1.7e-35 121.6 0.2 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KOS18205.1 - 1.3e-12 47.5 0.1 1.7e-12 47.1 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family FAD-oxidase_C PF02913.14 KOS18206.1 - 6e-56 189.5 0.0 1e-55 188.7 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KOS18206.1 - 1.4e-35 121.7 0.1 2.9e-35 120.7 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 KOS18206.1 - 0.019 13.4 0.1 0.039 12.4 0.0 1.5 2 0 0 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) RdRP PF05183.7 KOS18207.1 - 1.2e-25 90.3 0.0 1.6e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Fumble PF03630.9 KOS18209.1 - 9.2e-132 439.0 0.2 9.9e-131 435.6 0.1 2.0 1 1 0 1 1 1 1 Fumble MIP-T3 PF10243.4 KOS18209.1 - 0.4 9.1 2.7 0.56 8.6 1.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3669 PF12417.3 KOS18210.1 - 5.2e-10 38.9 0.0 1.4e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Zinc finger protein RGS PF00615.14 KOS18211.1 - 1.2e-06 28.5 0.0 0.002 18.2 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Anoctamin PF04547.7 KOS18212.1 - 7.8e-116 387.3 2.5 1e-115 387.0 1.7 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Metallophos PF00149.23 KOS18213.1 - 9.5e-08 31.6 5.3 1.3e-06 27.9 3.7 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KOS18213.1 - 1.2e-05 25.2 0.1 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_1_2 PF00155.16 KOS18214.1 - 4.3e-58 197.0 0.0 4.9e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_76 PF03663.9 KOS18217.1 - 5.8e-128 427.3 6.7 7.2e-128 427.0 4.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KOS18217.1 - 6e-05 22.2 5.7 0.0084 15.1 0.4 3.4 4 0 0 4 4 4 2 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 KOS18217.1 - 0.13 10.4 0.9 7.3 4.7 0.1 2.7 2 1 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) FA_hydroxylase PF04116.8 KOS18218.1 - 6.6e-16 58.7 17.7 6.6e-16 58.7 12.3 2.2 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Adeno_GP19K PF04881.8 KOS18218.1 - 0.055 13.2 0.3 0.087 12.5 0.2 1.4 1 0 0 1 1 1 0 Adenovirus GP19K NCA2 PF08637.5 KOS18219.1 - 4.2e-86 288.4 0.0 7.1e-86 287.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.1 KOS18219.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 APH PF01636.18 KOS18220.1 - 0.035 13.8 1.5 0.31 10.7 1.0 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.11 KOS18221.1 - 3.7e-35 121.2 34.8 3.7e-35 121.2 24.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SKG6 PF08693.5 KOS18222.1 - 0.051 12.8 0.1 0.051 12.8 0.1 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain PIP5K PF01504.13 KOS18223.1 - 4.1e-86 288.1 0.3 6.8e-86 287.4 0.2 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase V-SNARE PF05008.10 KOS18223.1 - 0.043 13.9 1.3 0.1 12.7 0.9 1.6 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus COX6B PF02297.12 KOS18224.1 - 1.9e-20 72.6 1.7 2.7e-20 72.1 1.1 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb SYS1 PF09801.4 KOS18225.1 - 7.9e-47 158.8 3.8 9.3e-47 158.6 2.6 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF412 PF04217.8 KOS18225.1 - 2.3 8.0 5.2 0.22 11.2 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF412 CPSF100_C PF13299.1 KOS18226.1 - 5.4e-42 143.7 0.3 5.4e-42 143.7 0.2 1.7 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KOS18226.1 - 2.4e-26 92.1 0.0 5.9e-26 90.8 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 KOS18226.1 - 6.6e-06 25.8 0.0 1.7e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Nucleoplasmin PF03066.10 KOS18226.1 - 0.02 14.4 0.3 0.02 14.4 0.2 2.8 4 0 0 4 4 4 0 Nucleoplasmin NAD_binding_6 PF08030.7 KOS18227.1 - 3.6e-32 111.4 0.0 7.7e-32 110.3 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KOS18227.1 - 2.5e-19 69.0 0.0 7.9e-19 67.4 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 KOS18227.1 - 9.2e-15 54.8 9.9 9.2e-15 54.8 6.9 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KOS18227.1 - 0.022 14.8 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KOS18227.1 - 0.11 13.0 0.0 0.64 10.6 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain UQ_con PF00179.21 KOS18228.1 - 5.3e-43 145.8 0.0 5.8e-43 145.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS18228.1 - 2.6e-05 23.9 0.0 3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KOS18228.1 - 0.00087 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KOS18228.1 - 0.0057 16.3 0.0 0.0092 15.6 0.0 1.3 1 0 0 1 1 1 1 UEV domain AlaDh_PNT_N PF05222.10 KOS18229.1 - 3.2e-19 69.2 0.0 4.7e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KOS18229.1 - 1e-12 47.9 0.0 1.5e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Acyl-CoA_dh_1 PF00441.19 KOS18230.1 - 4.6e-24 85.2 0.8 6.8e-24 84.6 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KOS18230.1 - 7.4e-23 81.2 0.2 1.6e-22 80.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KOS18230.1 - 1.3e-15 56.5 0.0 2.9e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KOS18230.1 - 1.2e-08 35.3 0.5 1.9e-08 34.6 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Methyltransf_12 PF08242.7 KOS18231.1 - 1.6e-13 50.9 0.0 4.8e-13 49.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS18231.1 - 9.9e-12 45.1 0.0 2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS18231.1 - 1.6e-10 40.9 0.0 2.5e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS18231.1 - 3.5e-09 36.9 0.0 6.6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS18231.1 - 3.2e-07 30.9 0.0 5.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS18231.1 - 8.6e-07 28.6 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KOS18231.1 - 2e-06 27.1 0.0 2.8e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KOS18231.1 - 0.0001 22.3 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KOS18231.1 - 0.00033 20.3 0.0 0.0056 16.3 0.0 2.3 1 1 0 1 1 1 1 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.12 KOS18231.1 - 0.0006 18.8 0.0 0.34 9.8 0.0 2.2 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family FmrO PF07091.6 KOS18231.1 - 0.00076 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) MTS PF05175.9 KOS18231.1 - 0.0033 16.8 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 KOS18231.1 - 0.004 17.9 0.0 0.011 16.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.3 KOS18231.1 - 0.044 12.5 0.0 0.071 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_16 PF10294.4 KOS18231.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Polyketide_cyc PF03364.15 KOS18232.1 - 5.9e-23 81.2 0.0 8.8e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 KOS18232.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.5 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DPM2 PF07297.7 KOS18233.1 - 4.5e-36 122.9 2.3 5.3e-36 122.7 1.6 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4229 PF14012.1 KOS18233.1 - 0.00047 19.9 1.4 0.00047 19.9 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) PIG-P PF08510.7 KOS18233.1 - 0.00055 19.5 0.7 0.00063 19.3 0.5 1.1 1 0 0 1 1 1 1 PIG-P Permease PF02405.11 KOS18233.1 - 0.0038 16.7 0.1 0.0038 16.7 0.0 1.5 2 0 0 2 2 2 1 Permease DUF4083 PF13314.1 KOS18233.1 - 0.031 14.0 2.1 0.035 13.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF1049 PF06305.6 KOS18233.1 - 0.052 13.0 0.8 0.052 13.0 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF1469 PF07332.6 KOS18233.1 - 0.24 11.1 7.5 0.45 10.2 5.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) PspC PF04024.7 KOS18233.1 - 2.5 7.6 6.4 12 5.4 0.6 2.2 2 0 0 2 2 2 0 PspC domain HAMP PF00672.20 KOS18233.1 - 4.8 7.4 6.9 3.8 7.7 0.2 2.1 2 0 0 2 2 2 0 HAMP domain TPPK_C PF12555.3 KOS18233.1 - 6.6 6.5 8.2 8.8 6.1 0.7 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal SR-25 PF10500.4 KOS18234.1 - 2.6 7.4 11.0 3 7.2 7.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 KOS18234.1 - 5.6 7.0 14.6 7.5 6.6 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SSP160 PF06933.6 KOS18234.1 - 8.1 4.2 9.1 7.7 4.3 6.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Abhydrolase_3 PF07859.8 KOS18235.1 - 4.3e-45 153.8 0.6 9.5e-44 149.4 0.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KOS18235.1 - 0.00028 19.7 0.0 0.00066 18.5 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KOS18235.1 - 0.0086 15.8 0.2 0.015 15.0 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF218 PF02698.12 KOS18235.1 - 0.076 12.5 0.0 3.1 7.2 0.0 2.7 2 1 1 3 3 3 0 DUF218 domain Peptidase_S9 PF00326.16 KOS18235.1 - 0.15 11.2 0.0 0.9 8.7 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ribosomal_60s PF00428.14 KOS18235.1 - 0.47 10.8 5.6 0.82 10.1 0.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DNA_pol3_theta PF06440.6 KOS18238.1 - 0.014 15.0 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase III, theta subunit Epimerase PF01370.16 KOS18239.1 - 9.4e-18 64.5 0.0 1.2e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KOS18239.1 - 9.5e-08 32.2 0.1 3.3e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KOS18239.1 - 1.6e-07 30.5 0.0 2.5e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KOS18239.1 - 3.7e-07 29.1 0.0 5.3e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KOS18239.1 - 8.7e-06 25.1 0.0 0.00022 20.5 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 KOS18239.1 - 0.0034 17.3 1.1 0.0052 16.7 0.3 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KOS18239.1 - 0.0057 15.5 0.1 0.0078 15.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF2742 PF10888.3 KOS18239.1 - 0.02 14.8 0.2 1.3 9.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) RmlD_sub_bind PF04321.12 KOS18239.1 - 0.035 12.9 0.1 0.069 12.0 0.1 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.5 KOS18239.1 - 0.045 13.4 0.2 0.089 12.4 0.1 1.5 1 0 0 1 1 1 0 KR domain ADH_zinc_N PF00107.21 KOS18240.1 - 8.7e-23 80.2 0.1 1.4e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KOS18240.1 - 3.1e-06 28.1 0.1 6.7e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PhoH PF02562.11 KOS18240.1 - 0.088 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Fringe PF02434.11 KOS18241.1 - 8.5e-08 31.7 0.0 1.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 KOS18241.1 - 0.00069 19.2 1.4 0.0018 17.9 0.9 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 KOS18241.1 - 0.02 14.6 0.1 0.041 13.6 0.1 1.4 1 0 0 1 1 1 0 PAN domain RTA1 PF04479.8 KOS18243.1 - 1.1e-31 110.0 8.5 1.6e-31 109.5 5.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF347 PF03988.7 KOS18243.1 - 0.39 10.6 0.1 0.39 10.6 0.1 3.3 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) 7TM-7TMR_HD PF07698.6 KOS18243.1 - 2.6 7.4 14.7 16 4.8 10.2 2.2 1 1 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Aldedh PF00171.17 KOS18244.1 - 3.1e-126 421.4 0.1 8.5e-126 419.9 0.1 1.5 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KOS18244.1 - 1.4e-05 23.9 0.0 3.6e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Rad60-SLD_2 PF13881.1 KOS18246.1 - 3.2e-12 46.3 0.0 4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KOS18246.1 - 5.3e-07 28.9 0.0 8.6e-07 28.2 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KOS18246.1 - 0.00032 20.8 0.0 0.0004 20.5 0.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Adaptin_N PF01602.15 KOS18247.1 - 3.2e-133 444.8 7.1 4.7e-133 444.2 4.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KOS18247.1 - 2.7e-18 66.4 0.3 2.7e-18 66.4 0.2 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KOS18247.1 - 3.6e-16 59.2 4.0 2.2e-09 37.4 0.1 4.7 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 KOS18247.1 - 8e-10 37.9 3.1 0.15 12.1 0.0 5.1 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KOS18247.1 - 0.00022 21.5 4.5 4.8 7.8 0.1 5.9 4 1 2 6 6 6 2 HEAT-like repeat Atx10homo_assoc PF09759.4 KOS18247.1 - 0.00039 20.1 0.0 0.089 12.5 0.0 3.8 3 1 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 KOS18247.1 - 0.003 16.9 1.0 2 7.7 0.0 3.3 2 1 1 3 3 3 2 CLASP N terminal Arm PF00514.18 KOS18247.1 - 0.0088 15.8 2.6 1.5 8.7 0.0 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 KOS18247.1 - 0.013 15.3 0.3 0.5 10.3 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) T_hemolysin PF12261.3 KOS18247.1 - 0.028 13.9 0.2 0.79 9.2 0.0 2.2 2 0 0 2 2 2 0 Thermostable hemolysin DUF1077 PF06417.7 KOS18248.1 - 1.9e-53 179.1 2.1 2.3e-53 178.8 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Syntaxin-18_N PF10496.4 KOS18249.1 - 1.9e-12 46.8 0.2 9.1e-12 44.6 0.0 2.2 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 KOS18249.1 - 0.011 15.3 0.8 0.011 15.3 0.5 2.8 3 0 0 3 3 3 0 SNARE domain CENP-H PF05837.7 KOS18249.1 - 0.49 10.5 7.2 4.4 7.5 0.3 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) BLOC1_2 PF10046.4 KOS18249.1 - 1.1 9.4 6.1 2.7 8.2 1.0 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Aminotran_1_2 PF00155.16 KOS18250.1 - 1.1e-83 281.1 0.0 1.3e-83 281.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RHH_1 PF01402.16 KOS18251.1 - 0.06 13.2 0.1 0.095 12.6 0.1 1.3 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family NMD3 PF04981.8 KOS18252.1 - 3.4e-72 242.3 1.7 5.2e-72 241.7 1.2 1.3 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.3 KOS18252.1 - 0.002 17.9 1.6 0.71 9.8 0.1 2.9 2 0 0 2 2 2 2 Rubredoxin-like zinc ribbon domain (DUF35_N) HypA PF01155.14 KOS18252.1 - 1.2 8.8 6.3 25 4.5 2.4 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 KOS18252.1 - 3.3 7.5 12.5 0.84 9.4 1.3 3.1 2 1 0 2 2 2 0 zinc-ribbons FYVE PF01363.16 KOS18252.1 - 4.5 7.2 9.9 15 5.5 0.4 2.6 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.2 KOS18252.1 - 5.7 6.8 13.1 6.5 6.6 0.2 2.9 2 1 0 2 2 2 0 Double zinc ribbon RRM_6 PF14259.1 KOS18253.1 - 0.0002 21.2 0.2 0.00082 19.3 0.0 2.2 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS18253.1 - 0.00027 20.5 0.0 0.03 13.9 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS18253.1 - 0.025 14.4 0.0 0.23 11.3 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAR2 PF05282.6 KOS18253.1 - 0.051 12.5 0.5 0.097 11.5 0.3 1.4 1 0 0 1 1 1 0 AAR2 protein cobW PF02492.14 KOS18254.1 - 4.9e-44 149.8 0.1 6.4e-44 149.5 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 KOS18254.1 - 0.0041 16.5 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain CobW_C PF07683.9 KOS18254.1 - 0.0076 15.9 0.1 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Miro PF08477.8 KOS18254.1 - 0.0081 16.6 0.1 0.89 10.0 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_19 PF13245.1 KOS18254.1 - 0.014 15.1 0.1 0.037 13.7 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 KOS18254.1 - 0.019 13.7 1.1 1.4 7.6 0.0 2.6 3 0 0 3 3 3 0 ArgK protein ATP_bind_1 PF03029.12 KOS18254.1 - 0.021 14.3 0.5 0.14 11.7 0.3 2.0 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 KOS18254.1 - 0.021 15.1 0.1 0.052 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KOS18254.1 - 0.021 14.7 0.6 0.077 12.9 0.4 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 KOS18254.1 - 0.026 14.4 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KOS18254.1 - 0.029 14.5 0.2 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KOS18254.1 - 0.043 13.4 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 KOS18254.1 - 0.045 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KOS18254.1 - 0.046 13.1 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 KOS18254.1 - 0.057 12.9 0.0 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 KOS18254.1 - 0.085 11.7 0.5 0.25 10.2 0.1 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF258 PF03193.11 KOS18254.1 - 0.085 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 KOS18254.1 - 0.098 12.2 0.4 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KOS18254.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 KOS18254.1 - 0.14 11.1 0.1 11 4.9 0.0 2.3 2 0 0 2 2 2 0 Septin ABC_tran PF00005.22 KOS18254.1 - 0.14 12.4 0.1 0.63 10.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter NOT2_3_5 PF04153.13 KOS18255.1 - 5e-33 113.8 1.1 7.7e-33 113.2 0.7 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CUE PF02845.11 KOS18256.1 - 6e-10 38.4 0.0 8.9e-10 37.8 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF2768 PF10966.3 KOS18256.1 - 0.57 10.3 2.6 0.46 10.6 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) DnaJ PF00226.26 KOS18257.1 - 1e-21 76.4 2.1 2.7e-21 75.0 1.4 1.8 1 0 0 1 1 1 1 DnaJ domain PBP1_TM PF14812.1 KOS18257.1 - 5.1 7.4 12.3 8.7 6.7 1.6 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SMC_N PF02463.14 KOS18258.1 - 4.6e-71 238.5 0.0 6.2e-70 234.8 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KOS18258.1 - 2.2e-22 79.2 1.6 9.8e-22 77.1 0.3 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KOS18258.1 - 1.1e-12 48.5 1.5 1.9e-05 24.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain MscS_porin PF12795.2 KOS18258.1 - 6.7e-05 22.3 18.1 6.7e-05 22.3 12.6 6.9 4 2 2 6 6 6 2 Mechanosensitive ion channel porin domain AAA_29 PF13555.1 KOS18258.1 - 0.0009 18.7 0.1 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain COG2 PF06148.6 KOS18258.1 - 0.004 17.0 3.3 0.004 17.0 2.3 9.1 6 2 3 10 10 10 1 COG (conserved oligomeric Golgi) complex component, COG2 ABC_tran PF00005.22 KOS18258.1 - 0.046 14.0 0.0 0.046 14.0 0.0 5.5 3 2 0 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 KOS18258.1 - 0.07 12.2 32.8 0.023 13.8 1.7 5.7 3 2 5 8 8 8 0 Reovirus sigma C capsid protein AAA_15 PF13175.1 KOS18258.1 - 5.5 5.9 23.1 0.071 12.1 5.4 3.8 3 1 0 3 3 3 0 AAA ATPase domain MOSC PF03473.12 KOS18259.1 - 3.6e-16 58.8 0.0 7.3e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 KOS18259.1 - 1.6e-06 27.7 0.0 3.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Mob1_phocein PF03637.12 KOS18261.1 - 3e-26 92.1 0.3 5.1e-26 91.4 0.2 1.2 1 0 0 1 1 1 1 Mob1/phocein family INCENP_ARK-bind PF03941.10 KOS18262.1 - 9.1e-21 73.4 1.0 1.8e-20 72.5 0.7 1.5 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region IBN_N PF03810.14 KOS18264.1 - 6.8e-09 35.5 0.0 1.4e-07 31.3 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KOS18264.1 - 0.0011 18.9 0.3 0.007 16.2 0.0 2.5 2 1 0 2 2 2 1 Exportin 1-like protein Cse1 PF08506.5 KOS18264.1 - 0.044 12.3 0.1 0.13 10.8 0.0 1.7 2 0 0 2 2 2 0 Cse1 DUF3844 PF12955.2 KOS18265.1 - 3e-29 101.1 2.4 5.5e-29 100.2 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 KOS18265.1 - 2.9 8.1 10.5 10 6.4 7.3 2.0 1 1 0 1 1 1 0 EGF-like domain adh_short PF00106.20 KOS18266.1 - 2.9e-25 89.1 1.0 4.2e-25 88.5 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS18266.1 - 9e-14 51.8 0.0 1.2e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS18266.1 - 5.2e-09 36.0 0.6 6.8e-09 35.6 0.4 1.1 1 0 0 1 1 1 1 KR domain RabGAP-TBC PF00566.13 KOS18267.1 - 3.3e-44 150.9 0.0 6.7e-44 149.9 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Myosin_tail_1 PF01576.14 KOS18267.1 - 0.0001 20.2 5.7 0.0001 20.2 3.9 2.3 2 0 0 2 2 2 1 Myosin tail ATG16 PF08614.6 KOS18267.1 - 0.0074 16.1 5.7 0.0074 16.1 3.9 4.1 5 0 0 5 5 5 2 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.14 KOS18267.1 - 0.17 9.7 3.8 0.069 10.9 0.6 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 KOS18267.1 - 0.29 9.4 4.4 1.2 7.4 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 KOS18267.1 - 0.55 10.3 7.4 0.13 12.3 1.6 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.3 KOS18267.1 - 1 8.5 10.2 0.028 13.6 2.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Laminin_II PF06009.7 KOS18267.1 - 1.6 8.4 10.4 1.4 8.6 0.3 2.9 2 1 1 3 3 3 0 Laminin Domain II DUF4618 PF15397.1 KOS18267.1 - 1.8 7.8 11.3 5.9 6.1 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF1664 PF07889.7 KOS18267.1 - 4.6 7.0 5.8 3.2 7.5 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Reticulon PF02453.12 KOS18268.1 - 1.3e-31 109.4 4.6 5.7e-31 107.3 1.8 2.0 2 0 0 2 2 2 1 Reticulon DUF2946 PF11162.3 KOS18268.1 - 0.011 15.9 0.4 0.035 14.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) CBP PF12192.3 KOS18268.1 - 0.94 9.4 4.7 0.19 11.7 0.4 1.9 2 0 0 2 2 2 0 Fungal calcium binding protein Ion_trans PF00520.26 KOS18269.1 - 2e-05 23.9 23.5 0.0012 18.1 16.3 2.3 1 1 0 1 1 1 1 Ion transport protein DNA_topoisoIV PF00521.15 KOS18270.1 - 2.1e-119 399.1 0.2 5.7e-119 397.7 0.0 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KOS18270.1 - 4.1e-32 110.7 0.7 8.8e-32 109.6 0.5 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KOS18270.1 - 1.2e-13 50.8 0.1 6.3e-13 48.5 0.0 2.3 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 KOS18270.1 - 2.4e-08 33.6 0.0 5.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TAP42 PF04177.7 KOS18271.1 - 7.7e-85 284.8 0.0 8.7e-85 284.6 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family DEK_C PF08766.6 KOS18273.1 - 0.013 15.2 0.3 0.35 10.6 0.0 2.5 2 0 0 2 2 2 0 DEK C terminal domain Gpi1 PF05024.10 KOS18274.1 - 4.2e-63 212.4 6.4 4.2e-63 212.4 4.4 2.0 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.16 KOS18274.1 - 0.00075 18.7 0.1 0.00075 18.7 0.1 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Trypan_PARP PF05887.6 KOS18275.1 - 0.04 13.7 0.7 0.04 13.7 0.5 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) TBCC PF07986.7 KOS18276.1 - 3.1e-31 107.2 0.0 5.6e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C Med9 PF07544.8 KOS18277.1 - 3.5e-21 74.7 0.0 2e-20 72.3 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 PEP-utilisers_N PF05524.8 KOS18277.1 - 0.0014 18.4 0.2 0.0014 18.4 0.2 1.5 2 0 0 2 2 2 1 PEP-utilising enzyme, N-terminal iPGM_N PF06415.8 KOS18278.1 - 1.8e-70 236.7 0.0 2.4e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 KOS18278.1 - 6.2e-66 222.3 0.0 7.7e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 KOS18278.1 - 4.2e-07 29.6 0.0 8.2e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KOS18278.1 - 1.8e-05 24.0 0.0 0.00031 20.0 0.0 2.2 1 1 0 1 1 1 1 Sulfatase AP_endonuc_2 PF01261.19 KOS18278.1 - 0.0068 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Prenylcys_lyase PF07156.9 KOS18279.1 - 7.6e-27 94.1 0.0 5.6e-26 91.2 0.0 2.1 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 KOS18279.1 - 7.6e-10 38.6 0.3 3.6e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KOS18279.1 - 3.6e-08 32.9 0.0 7.8e-08 31.8 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 KOS18279.1 - 0.025 13.4 0.0 0.13 11.1 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF3767 PF12597.3 KOS18281.1 - 2e-35 121.0 1.0 4.5e-35 119.8 0.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) DUF3529 PF12046.3 KOS18281.1 - 0.00094 18.2 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3529) Aldose_epim PF01263.15 KOS18282.1 - 4.6e-62 209.8 0.0 5.4e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase ABC_tran PF00005.22 KOS18283.1 - 9.9e-32 110.1 1.7 1.1e-19 71.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KOS18283.1 - 7.2e-10 39.2 0.7 0.035 14.0 0.0 3.3 3 0 0 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 KOS18283.1 - 4.4e-07 29.6 3.1 4.4e-07 29.6 2.2 2.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 KOS18283.1 - 2e-05 23.9 5.5 0.024 13.8 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 KOS18283.1 - 0.0036 17.7 0.0 0.012 16.0 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 KOS18283.1 - 0.0069 15.2 0.1 0.014 14.2 0.1 1.4 1 0 0 1 1 1 1 ArgK protein AAA_33 PF13671.1 KOS18283.1 - 0.0087 15.9 0.1 0.033 14.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 KOS18283.1 - 0.018 14.8 0.1 0.018 14.8 0.0 2.1 3 0 0 3 3 3 0 Dynamin family AAA_17 PF13207.1 KOS18283.1 - 0.034 14.9 2.2 0.059 14.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 KOS18283.1 - 0.051 13.2 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KOS18283.1 - 0.059 13.3 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KOS18283.1 - 0.065 12.7 0.2 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 KOS18283.1 - 0.074 12.4 2.7 0.25 10.7 0.2 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 KOS18283.1 - 0.16 12.1 6.0 0.47 10.6 0.3 3.5 3 1 0 3 3 3 0 AAA domain NDT80_PhoG PF05224.7 KOS18285.1 - 2.2e-42 145.1 0.0 2.9e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Abhydrolase_6 PF12697.2 KOS18287.1 - 9.4e-26 91.0 0.0 6.8e-25 88.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS18287.1 - 1.2e-13 51.1 0.0 4.1e-12 46.1 0.0 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS18287.1 - 4.2e-11 42.7 0.0 8e-10 38.6 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KOS18287.1 - 6.7e-05 22.0 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 KOS18287.1 - 0.00015 21.2 0.1 0.00033 20.1 0.1 1.6 1 1 0 1 1 1 1 Putative esterase Lipase_3 PF01764.20 KOS18287.1 - 0.0017 17.9 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 KOS18287.1 - 0.0018 17.7 0.0 1.6 8.1 0.0 2.6 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 KOS18287.1 - 0.011 15.5 0.0 0.033 14.0 0.0 1.7 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 KOS18287.1 - 0.013 15.0 0.0 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.15 KOS18287.1 - 0.036 14.2 0.1 0.14 12.3 0.1 2.0 1 1 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.6 KOS18287.1 - 0.039 13.6 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.2 KOS18287.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme UPF0227 PF05728.7 KOS18287.1 - 0.18 11.5 0.0 0.71 9.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) PEP_mutase PF13714.1 KOS18288.1 - 1e-36 126.3 1.3 1.2e-36 126.1 0.9 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KOS18288.1 - 1.2e-17 63.3 0.3 1.4e-17 63.1 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family TRM PF02005.11 KOS18289.1 - 2.5e-101 339.3 0.0 2.9e-90 302.9 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 KOS18289.1 - 0.00027 20.9 0.1 0.00064 19.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain DZR PF12773.2 KOS18289.1 - 0.035 13.9 0.1 0.83 9.5 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon Met_10 PF02475.11 KOS18289.1 - 0.039 13.5 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein zf-ribbon_3 PF13248.1 KOS18289.1 - 0.052 12.7 0.2 0.12 11.6 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Spo7 PF03907.8 KOS18290.1 - 2.3e-70 236.4 0.0 3.1e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein HET PF06985.6 KOS18291.1 - 1.9e-24 86.4 0.0 1.3e-23 83.6 0.0 2.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF221 PF02714.10 KOS18292.1 - 7.4e-94 314.2 26.0 7.4e-94 314.2 18.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KOS18292.1 - 2.1e-40 137.8 2.2 2.1e-40 137.8 1.6 3.8 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KOS18292.1 - 5e-17 61.5 0.0 1.1e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KOS18292.1 - 1.8e-09 38.0 6.9 2e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) HSP70 PF00012.15 KOS18294.1 - 6.5e-265 879.7 13.3 7.5e-265 879.5 9.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KOS18294.1 - 1.8e-14 53.1 4.1 1.7e-12 46.6 0.8 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KOS18294.1 - 0.0005 19.7 0.0 0.0015 18.1 0.0 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KOS18294.1 - 0.027 14.2 13.0 0.52 10.1 0.1 4.8 3 3 0 3 3 3 0 Cell division protein FtsA Spc97_Spc98 PF04130.8 KOS18295.1 - 5e-127 424.4 0.1 7.2e-127 423.9 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family SNF2_N PF00176.18 KOS18296.1 - 4.5e-67 225.9 0.0 6.6e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS18296.1 - 3.1e-10 39.7 0.0 6.5e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KOS18296.1 - 4.8e-06 26.1 2.1 1.1e-05 25.0 1.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 KOS18296.1 - 6.2e-06 25.8 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 KOS18296.1 - 0.00032 20.4 2.0 0.0011 18.7 1.4 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KOS18296.1 - 0.0035 16.9 1.4 0.01 15.4 0.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS18296.1 - 0.0066 16.4 0.7 0.0066 16.4 0.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KOS18296.1 - 0.046 13.5 0.0 0.15 11.8 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 KOS18296.1 - 0.41 10.3 10.3 0.016 14.8 2.5 2.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HemY_N PF07219.8 KOS18298.1 - 0.05 13.1 2.5 0.11 12.0 0.1 2.2 1 1 1 2 2 2 0 HemY protein N-terminus PIRT PF15099.1 KOS18298.1 - 0.054 12.7 1.0 0.1 11.8 0.7 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Herpes_gE PF02480.11 KOS18298.1 - 0.1 10.8 0.0 0.1 10.8 0.0 1.5 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Rax2 PF12768.2 KOS18298.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF2415 PF10313.4 KOS18299.1 - 2.8e-13 49.3 0.2 2.9e-12 46.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 KOS18299.1 - 0.23 11.3 2.7 41 4.2 0.1 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat DAO PF01266.19 KOS18300.1 - 1e-51 175.9 6.0 1.3e-51 175.6 4.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KOS18300.1 - 2.8e-06 27.2 0.1 8.7e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KOS18300.1 - 0.00057 19.9 0.0 0.0088 16.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KOS18300.1 - 0.029 13.4 0.8 0.11 11.5 0.1 2.0 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 KOS18300.1 - 0.035 13.0 0.2 0.059 12.2 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KOS18300.1 - 0.063 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KOS18300.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KOS18300.1 - 0.14 11.8 0.1 0.31 10.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.14 KOS18300.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase Fungal_trans_2 PF11951.3 KOS18301.1 - 0.15 10.5 0.9 0.18 10.3 0.3 1.3 2 0 0 2 2 2 0 Fungal specific transcription factor domain Proteasome PF00227.21 KOS18302.1 - 4e-56 189.3 0.1 5.2e-56 188.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KOS18302.1 - 1.6e-11 43.3 0.0 3.4e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 KOS18302.1 - 0.077 12.6 0.1 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) Ribosomal_L37e PF01907.14 KOS18303.1 - 1.5e-11 43.8 3.3 3.3e-11 42.7 2.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L37e ApbA PF02558.11 KOS18304.1 - 8e-24 83.8 0.0 1.2e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KOS18304.1 - 5.9e-17 61.8 0.0 8.8e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Sel1 PF08238.7 KOS18306.1 - 3.5e-42 141.8 26.1 6.7e-07 29.7 0.0 7.5 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.1 KOS18306.1 - 0.52 10.8 7.9 4.6 7.9 0.0 5.5 5 1 2 7 7 7 0 Tetratricopeptide repeat PAT1 PF09770.4 KOS18306.1 - 1.3 7.1 33.6 1.9 6.6 23.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 KOS18307.1 - 1.3e-37 129.3 33.4 4.7e-26 91.3 9.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS18307.1 - 4.3e-11 42.0 8.6 4.3e-11 42.0 5.9 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KOS18307.1 - 0.00011 20.5 4.7 0.00011 20.5 3.2 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2348 PF09807.4 KOS18308.1 - 0.016 14.3 0.2 0.099 11.7 0.0 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2348) A_deamin PF02137.13 KOS18309.1 - 2.9e-58 197.8 0.0 3.6e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain NAC PF01849.13 KOS18310.1 - 5e-21 73.9 0.1 9.3e-21 73.1 0.1 1.5 1 0 0 1 1 1 1 NAC domain Sigma70_r3 PF04539.11 KOS18310.1 - 0.093 12.6 0.3 0.27 11.1 0.2 1.8 1 0 0 1 1 1 0 Sigma-70 region 3 OPT PF03169.10 KOS18311.1 - 1.8e-172 575.0 56.2 2e-172 574.9 38.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 KOS18311.1 - 0.89 8.6 5.5 0.11 11.6 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) CBP4 PF07960.6 KOS18312.1 - 2.9e-33 114.1 2.1 3.3e-33 114.0 1.5 1.0 1 0 0 1 1 1 1 CBP4 4HB_MCP_1 PF12729.2 KOS18312.1 - 0.28 10.4 1.7 0.35 10.2 1.2 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction She9_MDM33 PF05546.6 KOS18312.1 - 0.3 10.6 5.6 0.39 10.2 3.9 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family PKK PF12474.3 KOS18312.1 - 1.3 8.6 10.4 1.8 8.2 7.2 1.1 1 0 0 1 1 1 0 Polo kinase kinase FA_desaturase PF00487.19 KOS18313.1 - 1.3e-39 136.2 23.2 1.8e-39 135.7 16.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KOS18313.1 - 4.9e-14 51.8 0.0 9.4e-14 50.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Xpo1 PF08389.7 KOS18313.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Exportin 1-like protein Pyr_redox_dim PF02852.17 KOS18314.1 - 6.7e-40 135.5 0.0 6.7e-40 135.5 0.0 2.7 4 0 0 4 4 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KOS18314.1 - 4.4e-37 127.9 12.6 1e-34 120.2 8.2 4.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS18314.1 - 2.3e-22 79.1 10.1 1.2e-20 73.6 1.3 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS18314.1 - 3.8e-10 39.6 3.3 2.2e-05 24.4 0.4 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KOS18314.1 - 1.5e-09 38.2 0.4 1e-05 25.7 0.4 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KOS18314.1 - 3.2e-09 36.3 7.7 6.2e-09 35.4 0.2 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 KOS18314.1 - 8.4e-09 34.7 9.6 3.1e-06 26.3 3.4 2.8 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KOS18314.1 - 4.4e-08 32.3 11.7 1.2e-06 27.6 2.4 3.3 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 KOS18314.1 - 4.3e-07 29.1 15.2 0.00045 19.2 0.4 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KOS18314.1 - 9.2e-06 24.3 14.4 0.0003 19.3 1.7 4.0 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 KOS18314.1 - 3.1e-05 23.0 0.1 0.089 11.6 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KOS18314.1 - 7.1e-05 22.0 7.6 0.001 18.2 1.2 2.5 2 1 0 2 2 2 2 Thi4 family AlaDh_PNT_C PF01262.16 KOS18314.1 - 7.2e-05 22.4 2.2 0.038 13.5 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KOS18314.1 - 0.0032 16.5 11.0 0.31 10.0 1.0 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.1 KOS18314.1 - 0.026 14.7 3.7 0.75 10.0 0.7 3.0 2 1 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KOS18314.1 - 0.059 12.5 1.2 2 7.5 0.2 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KOS18314.1 - 0.064 12.1 6.4 0.081 11.8 0.4 2.6 3 1 0 3 3 3 0 Lycopene cyclase protein Amino_oxidase PF01593.19 KOS18314.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 KOS18314.1 - 0.94 8.0 6.3 0.65 8.5 0.7 2.1 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 KOS18314.1 - 1.5 8.4 8.9 0.082 12.5 0.4 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Telomere_reg-2 PF10193.4 KOS18315.1 - 0.082 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Telomere length regulation protein DnaJ PF00226.26 KOS18316.1 - 2e-23 81.9 3.4 6.8e-23 80.1 2.4 2.0 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 KOS18316.1 - 3.7e-23 80.9 3.2 9.4e-09 34.8 0.0 5.3 3 2 2 5 5 5 5 TPR repeat TPR_16 PF13432.1 KOS18316.1 - 6.1e-18 64.9 1.3 0.00043 20.8 0.0 5.6 5 1 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS18316.1 - 6.3e-17 60.0 1.6 0.063 13.2 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 KOS18316.1 - 1.4e-16 59.2 0.6 0.0035 16.8 0.0 6.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 KOS18316.1 - 3e-12 45.4 0.0 0.0026 17.4 0.0 6.5 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KOS18316.1 - 8.9e-12 44.2 1.2 0.0022 18.0 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 KOS18316.1 - 9.6e-12 44.5 0.5 0.011 15.5 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KOS18316.1 - 1.1e-11 44.9 1.3 0.0015 18.7 0.2 4.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KOS18316.1 - 4.5e-11 42.3 5.2 0.22 12.2 0.0 7.3 3 3 5 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 KOS18316.1 - 1.5e-08 34.6 1.7 0.013 15.6 0.3 4.0 3 1 2 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KOS18316.1 - 7.3e-08 31.6 3.5 0.34 10.8 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KOS18316.1 - 2.1e-06 27.6 8.6 0.082 12.8 0.0 5.3 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 KOS18316.1 - 5e-06 26.6 5.6 3.8 8.1 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat PPTA PF01239.17 KOS18316.1 - 0.011 15.0 0.2 0.11 11.9 0.0 2.3 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat DUF4398 PF14346.1 KOS18316.1 - 0.67 10.0 23.8 0.05 13.6 1.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4398) TPR_21 PF09976.4 KOS18316.1 - 3.4 7.5 17.9 3.1 7.7 0.2 4.5 3 3 2 5 5 5 0 Tetratricopeptide repeat Laminin_II PF06009.7 KOS18317.1 - 0.044 13.5 0.2 0.081 12.6 0.1 1.4 1 0 0 1 1 1 0 Laminin Domain II GATase_7 PF13537.1 KOS18317.1 - 0.094 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain Striatin PF08232.7 KOS18317.1 - 0.1 12.9 0.4 0.1 12.9 0.2 1.8 2 0 0 2 2 2 0 Striatin family PspB PF06667.7 KOS18317.1 - 0.12 12.3 4.9 2.4 8.1 0.2 3.2 3 1 0 3 3 3 0 Phage shock protein B Vps5 PF09325.5 KOS18317.1 - 1.3 8.2 5.1 1.2 8.3 0.2 2.7 2 1 0 3 3 3 0 Vps5 C terminal like IncA PF04156.9 KOS18317.1 - 9.3 5.7 8.4 5.9 6.4 3.3 2.2 2 1 0 2 2 2 0 IncA protein Vac14_Fig4_bd PF11916.3 KOS18318.1 - 1.9e-81 271.5 3.5 1.9e-81 271.5 2.4 2.1 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KOS18318.1 - 2.2e-44 149.7 0.1 7.4e-41 138.4 0.0 3.5 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KOS18318.1 - 2.7e-09 36.3 1.3 0.0022 17.9 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 KOS18318.1 - 7e-06 26.2 2.6 0.11 12.8 0.0 4.7 4 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 KOS18318.1 - 2.2e-05 24.7 10.2 0.00054 20.3 0.0 5.3 5 1 0 5 5 5 1 HEAT-like repeat Arm PF00514.18 KOS18318.1 - 0.00088 19.0 0.0 0.73 9.7 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Glyoxalase_2 PF12681.2 KOS18319.1 - 0.0019 18.8 0.0 0.0035 17.9 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KOS18319.1 - 0.13 12.2 0.0 2.2 8.2 0.0 2.2 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EMG1 PF03587.9 KOS18320.1 - 3.5e-79 264.8 0.2 4.1e-79 264.5 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Ribosomal_S17 PF00366.15 KOS18321.1 - 6e-09 35.8 1.1 1.1e-08 35.0 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 RR_TM4-6 PF06459.7 KOS18321.1 - 0.0058 16.5 1.2 0.0063 16.4 0.8 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.6 KOS18321.1 - 0.012 13.9 1.0 0.013 13.8 0.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein NARP1 PF12569.3 KOS18321.1 - 0.056 12.1 5.4 0.067 11.9 3.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rtf2 PF04641.7 KOS18321.1 - 0.13 11.4 4.0 0.18 10.9 2.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DDRGK PF09756.4 KOS18321.1 - 5.1 6.4 12.6 7.4 5.9 8.8 1.1 1 0 0 1 1 1 0 DDRGK domain PXA PF02194.10 KOS18322.1 - 3.4e-35 121.2 0.1 4.7e-35 120.8 0.1 1.2 1 0 0 1 1 1 1 PXA domain zf-Mss51 PF13824.1 KOS18323.1 - 7.2e-26 89.8 4.6 1.4e-25 88.9 3.2 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KOS18323.1 - 0.0028 17.4 0.9 0.0046 16.7 0.6 1.3 1 0 0 1 1 1 1 MYND finger CPSF_A PF03178.10 KOS18324.1 - 4.4e-103 344.7 0.0 1.2e-102 343.3 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 KOS18324.1 - 2.7e-70 236.9 0.0 4e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 KOS18324.1 - 0.068 13.0 0.4 0.23 11.4 0.3 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat UBA_4 PF14555.1 KOS18325.1 - 2.8e-05 23.5 0.0 5.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.15 KOS18325.1 - 0.086 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 LysM domain DUF2360 PF10152.4 KOS18325.1 - 0.09 13.0 0.4 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF2040 PF09745.4 KOS18326.1 - 2.9e-38 130.5 22.5 2.9e-38 130.5 15.6 3.3 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) CXCR4_N PF12109.3 KOS18326.1 - 0.01 15.6 0.1 0.028 14.2 0.1 1.7 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal zf-Tim10_DDP PF02953.10 KOS18327.1 - 2.7e-22 77.8 1.6 3.3e-22 77.5 1.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2116 PF09889.4 KOS18327.1 - 0.086 12.6 2.4 0.39 10.5 0.3 2.2 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Lectin_leg-like PF03388.8 KOS18328.1 - 6.8e-65 218.4 0.0 8.3e-65 218.1 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KOS18328.1 - 0.0025 17.2 0.0 0.073 12.4 0.0 2.1 2 0 0 2 2 2 1 Legume lectin domain ATG27 PF09451.5 KOS18328.1 - 0.0032 16.7 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 COX16 PF14138.1 KOS18329.1 - 0.031 14.4 0.4 7.5 6.7 0.1 3.2 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 DUF4381 PF14316.1 KOS18329.1 - 0.057 13.5 0.2 1.6 8.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) TGS PF02824.16 KOS18331.1 - 7.8e-22 76.8 0.1 1.5e-21 75.9 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KOS18331.1 - 5.4e-18 65.0 0.0 1.1e-17 63.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS18331.1 - 1.4e-09 37.3 0.0 8.4e-09 34.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KOS18331.1 - 2.5e-05 23.7 0.1 0.51 9.7 0.0 3.9 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KOS18331.1 - 4.7e-05 23.2 0.1 0.013 15.3 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 KOS18331.1 - 0.0096 14.7 0.1 0.024 13.4 0.1 1.6 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 KOS18331.1 - 0.021 15.3 0.0 0.2 12.1 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AIG1 PF04548.11 KOS18331.1 - 0.062 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family DUF1524 PF07510.6 KOS18332.1 - 1.2e-12 47.8 0.0 1.5e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Cellulase PF00150.13 KOS18333.1 - 5.4e-21 75.0 3.1 7.3e-21 74.5 2.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 KOS18333.1 - 0.0022 17.1 0.3 0.027 13.5 0.1 2.0 2 0 0 2 2 2 1 Beta-galactosidase Cellulase-like PF12876.2 KOS18333.1 - 0.019 15.4 0.0 0.11 13.0 0.0 2.2 1 1 0 1 1 1 0 Sugar-binding cellulase-like DNA_mis_repair PF01119.14 KOS18334.1 - 5.5e-33 112.9 0.0 1e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KOS18334.1 - 8.8e-13 48.0 0.1 1.9e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KOS18334.1 - 4e-10 39.3 0.0 9.1e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lon_C PF05362.8 KOS18335.1 - 1.8e-67 226.6 0.1 3.6e-67 225.6 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KOS18335.1 - 5.1e-23 81.8 0.0 9.2e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KOS18335.1 - 3.9e-22 78.8 0.0 9.3e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 KOS18335.1 - 1.5e-08 34.1 0.0 1.3e-07 31.1 0.0 2.4 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 KOS18335.1 - 2.1e-08 33.9 0.0 6.1e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KOS18335.1 - 1.8e-05 24.7 1.6 4e-05 23.6 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 KOS18335.1 - 2e-05 24.2 0.0 5.1e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KOS18335.1 - 2.3e-05 25.1 0.0 0.0001 23.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.9 KOS18335.1 - 0.00022 21.1 0.0 0.0006 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KOS18335.1 - 0.00024 20.2 0.1 0.001 18.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KOS18335.1 - 0.0005 20.2 0.0 0.0057 16.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KOS18335.1 - 0.00083 18.8 0.0 0.0025 17.2 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KOS18335.1 - 0.0009 18.9 0.1 0.0038 16.9 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain AAA_25 PF13481.1 KOS18335.1 - 0.0017 17.8 0.0 0.0045 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KOS18335.1 - 0.0024 17.7 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KOS18335.1 - 0.0025 18.1 0.0 0.017 15.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS18335.1 - 0.0032 17.3 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KOS18335.1 - 0.0034 16.5 0.2 0.081 12.0 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KOS18335.1 - 0.0054 16.4 0.0 0.018 14.6 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 KOS18335.1 - 0.0061 16.1 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KOS18335.1 - 0.01 15.9 0.0 0.03 14.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 KOS18335.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KOS18335.1 - 0.015 15.6 0.1 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KOS18335.1 - 0.028 14.0 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 KOS18335.1 - 0.047 13.1 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain TIP49 PF06068.8 KOS18335.1 - 0.055 12.1 0.0 0.1 11.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus NB-ARC PF00931.17 KOS18335.1 - 0.062 12.1 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.20 KOS18335.1 - 0.062 12.7 0.7 37 3.7 0.0 3.5 4 0 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 KOS18335.1 - 0.068 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 KOS18335.1 - 0.082 12.6 0.1 0.21 11.2 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KOS18335.1 - 0.091 13.0 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 KOS18335.1 - 0.11 12.1 0.1 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 NTPase DUF3138 PF11336.3 KOS18335.1 - 0.4 8.7 3.0 0.61 8.1 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RPA_C PF08784.6 KOS18336.1 - 1.7e-14 54.0 1.0 2e-14 53.8 0.0 1.7 2 0 0 2 2 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KOS18336.1 - 2.2e-09 37.0 0.0 5.2e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain BLVR PF06375.6 KOS18336.1 - 0.0043 16.8 11.1 0.0063 16.3 7.7 1.2 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) NST1 PF13945.1 KOS18336.1 - 0.0058 16.7 4.8 0.0088 16.1 3.3 1.2 1 0 0 1 1 1 1 Salt tolerance down-regulator TraV PF09676.5 KOS18336.1 - 0.012 16.3 3.3 3.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Tubulin_3 PF14881.1 KOS18336.1 - 0.017 14.5 0.6 0.042 13.3 0.4 1.6 1 0 0 1 1 1 0 Tubulin domain Protocadherin PF08374.6 KOS18336.1 - 0.019 14.5 4.3 0.027 14.1 3.0 1.2 1 0 0 1 1 1 0 Protocadherin Ydc2-catalyt PF09159.5 KOS18336.1 - 0.02 14.3 2.2 0.026 14.0 1.5 1.2 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 NPR3 PF03666.8 KOS18336.1 - 0.26 9.7 3.1 0.36 9.3 2.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SR-25 PF10500.4 KOS18336.1 - 0.32 10.4 11.3 0.47 9.9 7.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3987 PF13148.1 KOS18336.1 - 1 7.8 4.4 1.3 7.5 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Peptidase_S49_N PF08496.5 KOS18336.1 - 2.8 7.7 10.3 4.9 6.9 7.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal APC_CDC26 PF10471.4 KOS18336.1 - 7.2 7.4 7.2 6.9 7.4 1.9 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 GATA PF00320.22 KOS18337.1 - 1.7e-15 56.0 2.8 2.9e-15 55.2 2.0 1.4 1 0 0 1 1 1 1 GATA zinc finger NARP1 PF12569.3 KOS18337.1 - 0.00035 19.4 5.2 0.00035 19.4 3.6 2.3 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TF_Zn_Ribbon PF08271.7 KOS18337.1 - 0.017 14.4 0.6 0.017 14.4 0.4 1.6 2 0 0 2 2 2 0 TFIIB zinc-binding Cwf_Cwc_15 PF04889.7 KOS18337.1 - 0.047 13.3 25.6 0.29 10.8 6.8 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Plasmodium_Vir PF05795.6 KOS18337.1 - 1.1 8.4 5.1 0.18 10.9 0.8 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Med15 PF09606.5 KOS18337.1 - 1.3 7.1 50.9 2 6.5 35.2 1.2 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM60A PF15396.1 KOS18337.1 - 2.1 8.0 16.2 0.04 13.6 4.7 2.3 2 1 0 2 2 2 0 Protein Family FAM60A Macoilin PF09726.4 KOS18337.1 - 3.2 5.9 37.8 9.7 4.3 26.2 1.7 1 1 0 1 1 1 0 Transmembrane protein OATP PF03137.15 KOS18337.1 - 3.5 5.5 8.1 5.4 4.9 5.6 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Rtf2 PF04641.7 KOS18337.1 - 4.3 6.4 21.9 0.37 9.9 5.4 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger Striatin PF08232.7 KOS18337.1 - 4.3 7.6 32.7 5.3 7.3 3.7 3.4 2 1 1 3 3 3 0 Striatin family AUX_IAA PF02309.11 KOS18337.1 - 5.3 6.7 17.4 2.2 7.9 5.4 2.2 2 0 0 2 2 2 0 AUX/IAA family Atg14 PF10186.4 KOS18337.1 - 6.5 5.6 30.1 2 7.2 9.0 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_S49_N PF08496.5 KOS18337.1 - 6.7 6.4 16.6 4.6 7.0 5.8 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Svf1 PF08622.5 KOS18338.1 - 1.5e-122 408.6 0.0 1.8e-122 408.4 0.0 1.0 1 0 0 1 1 1 1 Svf1-like Mit_KHE1 PF10173.4 KOS18339.1 - 4.6e-57 192.9 0.0 7.8e-57 192.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related DUF4589 PF15252.1 KOS18339.1 - 0.023 14.4 1.3 0.035 13.9 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) NUDIX PF00293.23 KOS18340.1 - 7.8e-27 93.5 0.0 1.1e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain HAD_2 PF13419.1 KOS18341.1 - 1.6e-25 90.3 0.2 1.9e-25 90.0 0.1 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS18341.1 - 4.4e-05 23.9 0.0 0.00021 21.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Med21 PF11221.3 KOS18342.1 - 1.7e-43 148.0 5.8 1.8e-43 147.9 4.0 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 KOS18342.1 - 0.0089 15.7 0.4 0.0089 15.7 0.3 2.7 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 TMCO5 PF14992.1 KOS18342.1 - 0.011 14.9 3.3 0.013 14.7 2.3 1.2 1 0 0 1 1 1 0 TMCO5 family Striatin PF08232.7 KOS18342.1 - 0.11 12.8 1.5 0.44 10.8 0.5 1.9 2 0 0 2 2 2 0 Striatin family GAS PF13851.1 KOS18342.1 - 0.18 11.0 5.2 1.1 8.3 0.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 KOS18342.1 - 0.26 11.4 2.5 0.77 9.8 1.6 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CtIP_N PF10482.4 KOS18342.1 - 0.31 10.8 6.0 2.3 8.0 1.7 2.4 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF1843 PF08898.5 KOS18342.1 - 0.42 10.7 3.3 0.78 9.8 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DnaG_DnaB_bind PF08278.6 KOS18342.1 - 0.48 10.6 7.3 0.51 10.5 0.7 2.8 1 1 1 2 2 2 0 DNA primase DnaG DnaB-binding CENP-Q PF13094.1 KOS18342.1 - 0.75 9.8 7.2 0.084 12.8 1.8 1.8 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Pup PF05639.6 KOS18342.1 - 0.94 10.0 4.3 1.3 9.5 1.4 2.1 2 0 0 2 2 2 0 Pup-like protein APG6 PF04111.7 KOS18342.1 - 4.2 6.3 6.3 7.1 5.5 4.4 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KOS18342.1 - 5.7 6.4 12.3 1.3 8.5 5.7 1.7 1 1 0 2 2 2 0 IncA protein Sec62 PF03839.11 KOS18343.1 - 5.3e-54 183.0 1.1 5.3e-54 183.0 0.7 1.9 2 0 0 2 2 2 1 Translocation protein Sec62 Acetyltransf_1 PF00583.19 KOS18344.1 - 6e-09 35.8 0.0 9.5e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KOS18344.1 - 5.3e-07 29.3 0.1 9.1e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KOS18344.1 - 1.1e-06 28.6 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS18344.1 - 4.5e-06 26.7 0.0 5.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS18344.1 - 0.0095 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PLDc_2 PF13091.1 KOS18345.1 - 3.5e-10 39.6 0.0 0.00021 21.0 0.0 3.5 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 KOS18345.1 - 2.4e-09 36.7 0.3 0.0012 18.5 0.0 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif Thioredoxin PF00085.15 KOS18346.1 - 4.1e-42 142.0 0.1 1.6e-23 82.3 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KOS18346.1 - 2.4e-11 43.7 0.0 0.00028 20.7 0.0 4.4 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KOS18346.1 - 8.4e-09 35.6 0.3 0.0047 17.1 0.0 4.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KOS18346.1 - 1.2e-06 28.5 1.5 0.011 15.8 0.0 4.6 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KOS18346.1 - 3.2e-06 27.0 0.1 0.00021 21.2 0.0 3.0 2 0 0 2 2 2 1 Thioredoxin-like Mitofilin PF09731.4 KOS18346.1 - 0.0027 16.4 5.3 0.0027 16.4 3.7 2.0 2 0 0 2 2 2 1 Mitochondrial inner membrane protein Thioredoxin_3 PF13192.1 KOS18346.1 - 0.0034 17.1 0.0 0.05 13.4 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin domain UBN_AB PF14075.1 KOS18346.1 - 0.013 15.1 0.6 0.013 15.1 0.4 2.3 2 0 0 2 2 2 0 Ubinuclein conserved middle domain AhpC-TSA PF00578.16 KOS18346.1 - 0.17 11.5 1.6 2.6 7.7 0.0 2.8 3 0 0 3 3 3 0 AhpC/TSA family Thioredoxin_9 PF14595.1 KOS18346.1 - 0.34 10.4 2.6 0.96 9.0 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin Tyr-DNA_phospho PF06087.7 KOS18347.1 - 4e-35 121.3 0.0 4.5e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase MatE PF01554.13 KOS18348.1 - 3.8e-50 169.6 30.5 2.2e-28 98.9 7.9 2.4 2 0 0 2 2 2 2 MatE 14-3-3 PF00244.15 KOS18349.1 - 5.4e-07 28.9 0.0 7.4e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 14-3-3 protein WD40 PF00400.27 KOS18350.1 - 1.7e-19 68.8 0.3 0.00011 21.9 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Prenyltrans PF00432.16 KOS18350.1 - 0.77 9.3 5.4 3.6 7.2 0.0 3.9 4 0 0 4 4 4 0 Prenyltransferase and squalene oxidase repeat Ribosomal_60s PF00428.14 KOS18350.1 - 1.7 9.0 12.2 3.3 8.1 8.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein FA_desaturase PF00487.19 KOS18351.1 - 2.4e-18 66.5 9.3 2.4e-18 66.5 6.4 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 KOS18351.1 - 1.1e-16 60.3 0.1 6.7e-16 57.8 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain TFIIB PF00382.14 KOS18352.1 - 7.1e-06 25.7 0.0 0.15 11.8 0.0 2.7 2 1 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_N PF00134.18 KOS18352.1 - 0.032 13.7 0.0 0.12 11.9 0.0 2.0 1 1 0 1 1 1 0 Cyclin, N-terminal domain Zn_clus PF00172.13 KOS18353.1 - 0.0002 21.1 7.0 0.0034 17.2 3.6 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Phasin PF05597.6 KOS18354.1 - 0.055 13.2 4.2 0.078 12.7 2.9 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF2229 PF09989.4 KOS18354.1 - 0.39 10.1 4.5 0.48 9.8 3.1 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) CAF-1_p150 PF11600.3 KOS18354.1 - 0.39 10.0 17.1 0.69 9.2 11.8 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal NAM-associated PF14303.1 KOS18354.1 - 1.7 8.9 13.7 2.2 8.5 9.5 1.3 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF3484 PF11983.3 KOS18354.1 - 3 8.7 6.9 9.7 7.1 4.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3484) DUF2034 PF10356.4 KOS18355.1 - 1e-30 106.2 0.0 9e-16 57.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KOS18355.1 - 1.1e-08 34.9 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Pkinase PF00069.20 KOS18356.1 - 1.5e-12 47.2 0.0 5.7e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS18356.1 - 3.2e-09 36.2 0.0 2.5e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase SSP160 PF06933.6 KOS18356.1 - 5.9 4.7 7.4 9.1 4.1 5.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Lon_C PF05362.8 KOS18357.1 - 9.8e-65 217.6 0.0 1.8e-64 216.8 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KOS18357.1 - 3.7e-37 128.0 0.1 8.8e-37 126.7 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KOS18357.1 - 4.2e-21 75.5 0.0 1.2e-20 74.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 KOS18357.1 - 2.1e-08 33.6 0.0 5.1e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 KOS18357.1 - 8.8e-07 28.7 0.0 2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KOS18357.1 - 2e-05 24.7 0.0 0.0003 20.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS18357.1 - 3.5e-05 23.8 1.5 0.006 16.5 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 KOS18357.1 - 6.3e-05 23.7 0.0 0.00041 21.1 0.0 2.5 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 KOS18357.1 - 6.3e-05 21.8 0.0 0.00013 20.8 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.7 KOS18357.1 - 0.00022 20.3 0.0 0.0016 17.5 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KOS18357.1 - 0.013 15.3 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KOS18357.1 - 0.034 14.4 0.0 0.034 14.4 0.0 2.6 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 KOS18357.1 - 0.038 13.6 0.0 0.12 12.0 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KOS18357.1 - 0.047 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 KOS18357.1 - 0.053 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KOS18357.1 - 0.055 12.8 0.0 0.2 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KOS18357.1 - 0.072 13.2 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase MOR2-PAG1_N PF14222.1 KOS18358.1 - 4.5e-216 718.8 0.0 1.3e-215 717.3 0.0 1.7 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KOS18358.1 - 2.8e-87 292.7 0.3 7.7e-87 291.3 0.0 2.0 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KOS18358.1 - 7.8e-36 123.1 7.2 1.9e-13 49.0 0.1 3.9 2 1 1 3 3 3 3 Cell morphogenesis central region HEAT_2 PF13646.1 KOS18358.1 - 0.048 13.9 7.7 2.6 8.4 0.0 6.5 9 0 0 9 9 9 0 HEAT repeats HEAT_EZ PF13513.1 KOS18358.1 - 0.08 13.4 2.9 0.33 11.5 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat CRM1_C PF08767.6 KOS18358.1 - 0.09 11.6 0.2 0.47 9.3 0.1 2.3 2 0 0 2 2 2 0 CRM1 C terminal DUF2151 PF10221.4 KOS18358.1 - 0.32 9.1 0.0 0.54 8.3 0.0 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator HEAT PF02985.17 KOS18358.1 - 1 9.5 4.0 12 6.2 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat FAD_binding_1 PF00667.15 KOS18359.1 - 3.3e-56 190.1 0.0 4.7e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KOS18359.1 - 1.1e-31 109.7 1.5 2.5e-31 108.6 1.1 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KOS18359.1 - 2.8e-21 76.1 0.0 2.6e-20 73.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KOS18359.1 - 0.024 14.6 0.0 0.09 12.7 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain Med5 PF08689.5 KOS18361.1 - 1.8e-153 512.6 0.0 1.4e-96 324.3 0.0 2.0 1 1 1 2 2 2 2 Mediator complex subunit Med5 adh_short PF00106.20 KOS18362.1 - 8.1e-18 64.8 1.3 2.5e-17 63.2 0.3 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KOS18362.1 - 8.6e-08 32.0 0.2 1.5e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 KR domain DIM PF08194.7 KOS18362.1 - 0.028 14.3 0.1 0.87 9.5 0.1 3.0 3 0 0 3 3 3 0 DIM protein ubiquitin PF00240.18 KOS18363.1 - 3.5e-18 64.7 0.1 6.5e-18 63.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KOS18363.1 - 3.8e-08 32.9 0.3 1.2e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 KOS18363.1 - 6.7e-06 25.7 0.1 1.1e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KOS18363.1 - 0.00032 20.5 0.1 0.00058 19.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KOS18363.1 - 0.048 13.8 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Helicase_C PF00271.26 KOS18364.1 - 0.0023 17.7 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-bind_6 PF13921.1 KOS18365.1 - 0.00014 21.8 1.0 0.00035 20.6 0.3 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KOS18365.1 - 0.0026 17.7 0.1 0.0059 16.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.7 KOS18365.1 - 0.0087 15.5 0.1 0.084 12.3 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_AsnC-type PF13404.1 KOS18365.1 - 0.075 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.11 KOS18365.1 - 0.076 12.3 0.0 0.27 10.5 0.0 2.0 1 1 0 1 1 1 0 Sigma-70, region 4 Sigma70_ECF PF07638.6 KOS18365.1 - 0.086 12.4 1.5 0.16 11.6 0.1 2.1 3 0 0 3 3 3 0 ECF sigma factor MADF_DNA_bdg PF10545.4 KOS18365.1 - 0.13 12.4 1.2 0.27 11.4 0.1 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Glyco_hydro_76 PF03663.9 KOS18366.1 - 5.3e-41 141.2 12.3 1.2e-40 140.0 3.4 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KOS18366.1 - 5.8e-06 25.5 0.1 0.33 9.9 0.0 3.3 2 1 0 3 3 3 3 Glycosyl Hydrolase Family 88 TFCD_C PF12612.3 KOS18367.1 - 5.5e-24 84.6 1.1 2.5e-23 82.5 0.0 2.8 2 1 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 KOS18367.1 - 0.0096 15.9 9.6 1.6 9.0 0.0 6.3 7 0 0 7 7 7 1 HEAT repeat Iso_dh PF00180.15 KOS18368.1 - 1.1e-96 323.7 0.0 6e-96 321.4 0.0 1.8 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SH3_9 PF14604.1 KOS18369.1 - 1e-12 47.4 1.7 6.7e-10 38.4 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain DUF3741 PF12552.3 KOS18369.1 - 0.084 12.6 0.9 0.21 11.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) GATase PF00117.23 KOS18371.1 - 9.2e-14 51.3 0.0 1.2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KOS18371.1 - 0.001 18.5 0.2 0.0037 16.7 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 KOS18371.1 - 0.0083 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Ribosomal_S4e PF00900.15 KOS18372.1 - 1.3e-31 108.0 0.2 2.9e-31 106.9 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KOS18372.1 - 8.4e-19 67.1 3.0 1.7e-18 66.1 2.0 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 KOS18372.1 - 3.5e-05 23.3 2.2 3.5e-05 23.3 1.5 3.1 4 0 0 4 4 4 1 KOW motif S4 PF01479.20 KOS18372.1 - 4.9e-05 22.6 0.0 9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain Cu-oxidase PF00394.17 KOS18373.1 - 2.1e-24 86.2 0.0 3.5e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KOS18373.1 - 1.2e-20 73.3 0.2 8.2e-17 61.0 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KOS18373.1 - 1.4e-17 63.4 2.4 4.6e-16 58.6 0.2 3.2 3 1 0 3 3 3 1 Multicopper oxidase DUF498 PF04430.9 KOS18373.1 - 0.1 12.1 0.0 0.67 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) DUF418 PF04235.7 KOS18374.1 - 0.031 13.9 1.8 0.052 13.2 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF418) Myb_DNA-binding PF00249.26 KOS18375.1 - 5.8e-10 39.0 0.6 4.6e-06 26.5 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KOS18375.1 - 2.3e-09 37.1 0.1 0.0014 18.6 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.5 KOS18375.1 - 0.0037 16.9 2.8 0.22 11.2 0.0 3.0 3 1 0 3 3 3 2 SLIDE Ebp2 PF05890.7 KOS18376.1 - 2e-95 319.1 10.6 2e-95 319.1 7.4 2.3 1 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 SLAC1 PF03595.12 KOS18377.1 - 2e-87 292.9 53.0 2.3e-87 292.7 36.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Phtf-FEM1B_bdg PF12129.3 KOS18377.1 - 0.69 9.2 2.9 0.35 10.2 0.3 1.8 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor CDO_I PF05995.7 KOS18378.1 - 8.3e-29 99.9 0.0 1.1e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KOS18378.1 - 0.0029 16.9 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) DinB PF05163.7 KOS18378.1 - 0.093 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 DinB family Metallophos PF00149.23 KOS18379.1 - 5.5e-44 149.9 0.9 5.5e-44 149.9 0.6 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Vps51 PF08700.6 KOS18380.1 - 1.7e-13 50.2 2.6 1.7e-13 50.2 1.8 2.2 2 0 0 2 2 2 1 Vps51/Vps67 DUF2383 PF09537.5 KOS18380.1 - 0.13 12.5 3.1 0.42 10.8 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) TSC22 PF01166.13 KOS18380.1 - 0.16 11.9 3.6 2.2 8.3 0.1 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family APG6 PF04111.7 KOS18380.1 - 0.29 10.1 14.6 0.28 10.2 4.7 2.4 2 0 0 2 2 2 0 Autophagy protein Apg6 Spc7 PF08317.6 KOS18380.1 - 0.5 8.9 10.1 2.1 6.9 0.9 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein SH3_9 PF14604.1 KOS18381.1 - 2.8e-06 26.8 0.3 5.3e-06 25.9 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KOS18381.1 - 0.0016 17.7 0.5 0.013 14.8 0.1 2.3 2 0 0 2 2 2 1 SH3 domain DUF2668 PF10873.3 KOS18381.1 - 0.0033 17.5 1.0 0.0033 17.5 0.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2668) CbiM PF01891.11 KOS18381.1 - 0.014 14.9 0.5 0.021 14.4 0.4 1.1 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region Glycophorin_A PF01102.13 KOS18381.1 - 0.05 13.3 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A Mid2 PF04478.7 KOS18381.1 - 0.051 12.9 0.1 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF912 PF06024.7 KOS18381.1 - 0.058 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SKG6 PF08693.5 KOS18381.1 - 0.12 11.6 1.2 0.24 10.7 0.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 KOS18381.1 - 0.22 11.1 0.5 0.41 10.3 0.4 1.3 1 0 0 1 1 1 0 Syndecan domain DUF3112 PF11309.3 KOS18382.1 - 1.1e-37 129.2 10.6 1.2e-33 116.1 0.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) MFS_2 PF13347.1 KOS18382.1 - 0.069 11.5 11.0 0.099 11.0 7.6 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein GILT PF03227.11 KOS18383.1 - 3e-14 52.7 0.0 4.4e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) MFS_1 PF07690.11 KOS18384.1 - 3.3e-22 78.7 30.5 3.4e-16 58.9 10.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3278 PF11683.3 KOS18384.1 - 0.03 14.3 0.0 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Sugar_tr PF00083.19 KOS18384.1 - 0.036 12.6 18.1 0.0067 15.0 4.1 3.1 3 0 0 3 3 3 0 Sugar (and other) transporter Myb_Cef PF11831.3 KOS18385.1 - 1.9e-56 190.9 4.3 1.9e-56 190.9 3.0 3.3 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KOS18385.1 - 4.2e-21 74.7 3.9 7.4e-10 38.7 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KOS18385.1 - 2e-20 72.6 9.1 5.9e-15 55.1 2.3 3.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain MAS20 PF02064.10 KOS18386.1 - 2.9e-13 49.7 0.3 9.4e-13 48.1 0.2 1.7 1 1 0 1 1 1 1 MAS20 protein import receptor SNF2_N PF00176.18 KOS18387.1 - 9e-52 175.7 0.0 1.2e-25 89.9 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Radical_SAM PF04055.16 KOS18387.1 - 8.2e-29 100.8 0.1 9.4e-27 94.2 0.1 2.8 2 0 0 2 2 2 1 Radical SAM superfamily Wyosine_form PF08608.7 KOS18387.1 - 1.7e-23 82.5 0.0 3.6e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 KOS18387.1 - 5.8e-08 32.8 0.8 3.1e-06 27.2 0.6 2.9 1 1 0 1 1 1 1 Flavodoxin Helicase_C PF00271.26 KOS18387.1 - 4.7e-07 29.5 0.0 1.7e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain NUDIX PF00293.23 KOS18388.1 - 1.8e-13 50.2 0.0 1e-11 44.6 0.0 3.0 2 1 0 2 2 2 1 NUDIX domain Pol_alpha_B_N PF08418.5 KOS18388.1 - 0.34 10.3 2.7 0.68 9.4 1.9 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Pheromone PF08015.6 KOS18388.1 - 5.1 7.9 13.7 0.25 12.1 3.7 2.8 2 0 0 2 2 2 0 Fungal mating-type pheromone Kisspeptin PF15152.1 KOS18388.1 - 8.8 7.1 8.3 5.7 7.6 1.4 2.5 2 0 0 2 2 2 0 Kisspeptin Pkinase PF00069.20 KOS18389.1 - 1.9e-50 171.4 0.0 2.6e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS18389.1 - 7.1e-24 84.2 0.0 1.2e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS18389.1 - 0.00016 21.5 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KOS18389.1 - 0.0015 17.9 0.2 0.0061 15.9 0.1 1.8 1 1 0 1 1 1 1 RIO1 family TFIIA PF03153.8 KOS18389.1 - 9.5 6.0 7.7 15 5.3 5.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Na_Ca_ex PF01699.19 KOS18390.1 - 1.1e-40 138.4 32.8 1.4e-20 73.3 9.5 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Pkinase PF00069.20 KOS18391.1 - 9.1e-64 215.1 0.0 1.7e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS18391.1 - 5.9e-36 123.8 0.0 7.8e-31 107.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KOS18391.1 - 2.6e-05 23.3 0.0 0.022 13.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KOS18391.1 - 0.013 15.2 0.5 0.023 14.4 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family CFTR_R PF14396.1 KOS18391.1 - 0.055 12.8 0.1 0.16 11.3 0.1 1.7 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain Kdo PF06293.9 KOS18391.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Levi_coat PF01819.12 KOS18391.1 - 0.075 12.6 1.0 0.54 9.8 0.1 2.4 2 0 0 2 2 2 0 Levivirus coat protein RIO1 PF01163.17 KOS18391.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pescadillo_N PF06732.6 KOS18392.1 - 1.2e-114 382.3 0.1 3.5e-114 380.8 0.1 1.7 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.21 KOS18392.1 - 4.4e-10 39.5 0.0 1.5e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Nop53 PF07767.6 KOS18392.1 - 0.18 10.7 32.9 0.014 14.4 17.7 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) EBV-NA3 PF05009.7 KOS18392.1 - 3.3 6.9 9.5 7.6 5.6 6.6 1.6 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CDC45 PF02724.9 KOS18392.1 - 6.6 4.6 26.2 13 3.6 18.1 1.5 1 0 0 1 1 1 0 CDC45-like protein RRN9 PF10680.4 KOS18393.1 - 9.3e-14 50.9 0.6 3.2e-13 49.2 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor zf-C2H2 PF00096.21 KOS18393.1 - 0.027 14.8 1.7 0.078 13.3 1.2 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2938 PF11158.3 KOS18393.1 - 0.085 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) zf-C2H2_4 PF13894.1 KOS18393.1 - 0.1 13.0 2.2 0.3 11.5 1.5 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger PPP4R2 PF09184.6 KOS18394.1 - 3.5e-10 39.8 6.5 1.8e-09 37.5 0.0 2.4 3 0 0 3 3 3 1 PPP4R2 Zip PF02535.17 KOS18394.1 - 0.78 8.6 3.1 1.2 8.0 2.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SPRY PF00622.23 KOS18395.1 - 3.5e-06 27.1 0.0 6.4e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 SPRY domain COesterase PF00135.23 KOS18396.1 - 6.2e-52 177.0 0.0 7.3e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KOS18396.1 - 0.00029 20.5 0.7 0.0016 18.0 0.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS18396.1 - 0.055 13.2 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 KOS18397.1 - 3.1e-30 105.4 0.1 5.9e-15 55.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KOS18397.1 - 0.00085 18.3 0.7 1.1 8.0 0.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KOS18397.1 - 0.0038 16.1 2.3 1.6 7.5 0.1 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox PF00070.22 KOS18397.1 - 0.0088 16.4 0.3 0.78 10.1 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS18397.1 - 0.016 15.1 0.0 0.051 13.6 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KOS18397.1 - 0.02 13.9 0.2 0.031 13.3 0.1 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.1 KOS18397.1 - 0.022 14.9 0.1 0.076 13.2 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 KOS18397.1 - 0.07 13.1 0.0 0.18 11.8 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2204 PF09970.4 KOS18397.1 - 0.094 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) Amino_oxidase PF01593.19 KOS18397.1 - 0.11 11.5 0.1 0.25 10.3 0.1 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KOS18397.1 - 0.19 11.4 1.2 5.4 6.7 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KOS18397.1 - 0.36 9.4 3.5 7.5 5.0 0.5 2.8 3 0 0 3 3 3 0 Tryptophan halogenase Tom37 PF10568.4 KOS18398.1 - 1.1e-20 73.6 0.1 2.1e-20 72.7 0.1 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Tom37_C PF11801.3 KOS18398.1 - 1.6e-20 73.6 0.0 2.5e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Tom37 C-terminal domain PIG-U PF06728.8 KOS18399.1 - 5.9e-121 403.9 21.0 6.8e-121 403.7 14.5 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.8 KOS18399.1 - 0.00033 20.4 2.6 0.00039 20.1 0.0 2.0 1 1 1 2 2 2 1 Mannosyltransferase (PIG-M) RRM_1 PF00076.17 KOS18400.1 - 2.3e-59 196.9 0.0 1.8e-21 75.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS18400.1 - 4.4e-44 148.3 0.0 7e-15 54.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS18400.1 - 3e-30 103.8 0.0 1.1e-10 41.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KOS18400.1 - 3.4e-07 29.9 0.0 0.016 14.9 0.0 3.5 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 KOS18400.1 - 0.0038 17.1 0.0 3.4 7.6 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) DUF572 PF04502.8 KOS18401.1 - 3.3 6.8 8.1 4.3 6.4 5.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.2 KOS18401.1 - 9.8 3.7 8.2 1.6 6.3 3.2 1.5 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Pkinase PF00069.20 KOS18402.1 - 1e-62 211.6 0.0 2.3e-62 210.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS18402.1 - 2.4e-28 98.9 0.0 4.2e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KOS18402.1 - 0.00012 21.2 0.0 0.00026 20.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KOS18402.1 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS18402.1 - 0.058 13.1 5.3 2 8.0 3.7 2.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF4662 PF15578.1 KOS18402.1 - 0.43 10.1 6.0 0.63 9.5 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) PPR_2 PF13041.1 KOS18403.1 - 6.1e-21 74.1 0.2 3.2e-15 55.8 0.0 3.7 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.1 KOS18403.1 - 2.5e-06 27.3 7.1 2.2 8.7 0.0 6.2 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.15 KOS18403.1 - 1.3e-05 24.8 2.5 0.0096 15.8 0.0 4.8 5 0 0 5 5 5 1 PPR repeat PPR_1 PF12854.2 KOS18403.1 - 0.0039 16.6 2.5 12 5.4 0.1 4.5 3 1 0 3 3 3 2 PPR repeat Chromate_transp PF02417.10 KOS18403.1 - 0.03 13.9 0.3 0.048 13.2 0.2 1.3 1 0 0 1 1 1 0 Chromate transporter TPR_11 PF13414.1 KOS18405.1 - 9.9e-36 121.2 27.8 2.3e-10 39.9 0.5 11.1 10 2 2 12 12 11 8 TPR repeat TPR_1 PF00515.23 KOS18405.1 - 4.4e-32 108.3 19.9 1.3e-05 24.5 0.2 11.6 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 KOS18405.1 - 1.1e-29 99.8 27.5 0.00037 20.1 0.1 12.4 12 0 0 12 12 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 KOS18405.1 - 1.6e-22 79.2 23.3 1.9e-08 34.0 0.2 10.4 8 3 4 12 12 11 7 Tetratricopeptide repeat TPR_8 PF13181.1 KOS18405.1 - 1.3e-20 71.5 22.7 4.6e-06 26.0 0.3 11.8 13 1 0 13 13 13 4 Tetratricopeptide repeat TPR_19 PF14559.1 KOS18405.1 - 3.1e-19 69.0 19.9 1.3e-05 25.4 0.1 10.1 8 3 1 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.1 KOS18405.1 - 8e-19 65.8 6.9 0.00095 18.7 0.0 10.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 KOS18405.1 - 1.8e-15 56.0 38.6 0.0008 19.8 0.1 14.3 14 3 3 17 17 15 5 Tetratricopeptide repeat TPR_16 PF13432.1 KOS18405.1 - 2.4e-13 50.3 35.3 0.013 16.1 0.0 11.7 8 2 5 13 13 13 5 Tetratricopeptide repeat TPR_6 PF13174.1 KOS18405.1 - 3.8e-10 39.5 17.5 0.26 11.8 0.0 10.3 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 KOS18405.1 - 4.4e-10 38.9 10.3 3.7 7.9 0.0 11.0 12 1 0 12 12 10 1 Tetratricopeptide repeat Apc3 PF12895.2 KOS18405.1 - 2e-09 37.4 15.4 0.0023 18.0 0.7 7.5 7 0 0 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KOS18405.1 - 5.9e-06 26.0 6.4 11 6.0 0.0 9.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_3 PF07720.7 KOS18405.1 - 3.1 7.7 10.5 39 4.1 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat FAD_binding_6 PF00970.19 KOS18406.1 - 5.3e-27 93.8 0.0 1e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KOS18406.1 - 3.9e-26 91.7 0.0 5.6e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KOS18406.1 - 3.2e-05 23.8 0.0 0.0033 17.3 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KOS18406.1 - 0.0098 15.8 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain GATase_4 PF13230.1 KOS18407.1 - 1.7e-14 53.1 0.0 3.1e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 KOS18407.1 - 7.8e-10 38.8 0.0 1.9e-09 37.5 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KOS18407.1 - 9.9e-07 27.7 0.3 8.2e-05 21.4 0.1 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II zf-C3HC4_2 PF13923.1 KOS18408.1 - 2e-08 34.1 16.5 0.00011 22.1 3.3 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS18408.1 - 4.8e-05 23.0 3.8 4.8e-05 23.0 2.6 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KOS18408.1 - 0.00014 21.6 13.7 0.0015 18.3 2.1 2.8 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KOS18408.1 - 0.00017 21.3 13.0 0.0024 17.6 2.8 2.6 2 0 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.1 KOS18408.1 - 0.0011 18.6 2.3 0.0018 17.9 0.5 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KOS18408.1 - 0.0021 17.6 4.1 0.0021 17.6 2.8 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KOS18408.1 - 0.37 10.7 13.3 0.68 9.8 2.8 3.2 2 1 1 3 3 3 0 FYVE zinc finger zf-RING_6 PF14835.1 KOS18408.1 - 0.56 10.0 13.2 2.3 8.0 1.9 3.0 3 0 0 3 3 3 0 zf-RING of BARD1-type protein mRNA_cap_enzyme PF01331.14 KOS18409.1 - 3e-51 173.8 0.3 4.1e-51 173.4 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KOS18409.1 - 1.3e-18 67.2 0.0 2.4e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KOS18409.1 - 1.7e-08 34.0 0.1 4.1e-07 29.5 0.1 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain PX PF00787.19 KOS18410.1 - 3.3e-19 68.7 0.0 1.2e-18 66.9 0.0 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KOS18410.1 - 1.8e-14 53.5 8.7 8.4e-09 35.0 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like DUF1675 PF07897.6 KOS18410.1 - 0.014 15.2 1.6 0.024 14.4 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Phosphonate-bd PF12974.2 KOS18411.1 - 7.7e-05 22.1 0.0 0.00012 21.5 0.0 1.4 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.6 KOS18411.1 - 0.00075 19.1 0.0 0.04 13.5 0.0 2.3 2 1 1 3 3 3 2 NMT1/THI5 like SBP_bac_3 PF00497.15 KOS18411.1 - 0.0059 15.8 0.0 0.051 12.8 0.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SBP_bac_11 PF13531.1 KOS18411.1 - 0.04 13.5 0.0 0.41 10.2 0.0 2.3 2 1 0 2 2 2 0 Bacterial extracellular solute-binding protein EamA PF00892.15 KOS18412.1 - 5.6e-08 32.8 21.1 8.8e-05 22.5 0.3 2.7 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KOS18412.1 - 1.2e-07 30.9 7.2 2.2e-07 30.1 5.0 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KOS18412.1 - 0.00047 19.8 17.1 0.079 12.6 0.7 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family Heme_oxygenase PF01126.15 KOS18413.1 - 4.2e-10 39.5 0.0 6.7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Heme oxygenase WD40 PF00400.27 KOS18414.1 - 8e-18 63.5 10.2 8.1e-05 22.3 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Pkinase PF00069.20 KOS18415.1 - 1.1e-77 260.7 0.0 1.3e-77 260.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS18415.1 - 3.4e-38 131.1 0.0 4.6e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS18415.1 - 0.0062 15.5 0.0 0.017 14.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Methyltransf_28 PF02636.12 KOS18416.1 - 2.1e-77 259.9 0.0 2.5e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Acyltransferase PF01553.16 KOS18417.1 - 1.1e-13 50.7 0.0 1.6e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DHquinase_I PF01487.10 KOS18417.1 - 0.13 11.9 0.1 5.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Type I 3-dehydroquinase Secretin_N_2 PF07655.8 KOS18418.1 - 0.71 10.2 8.6 1 9.7 6.0 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain SAP25 PF15476.1 KOS18418.1 - 0.91 8.9 9.9 0.73 9.3 6.3 1.3 1 1 0 1 1 1 0 Histone deacetylase complex subunit SAP25 Macoilin PF09726.4 KOS18418.1 - 1.1 7.4 4.4 1.1 7.4 3.1 1.0 1 0 0 1 1 1 0 Transmembrane protein MSP1_C PF07462.6 KOS18418.1 - 2.5 6.3 7.4 2.9 6.1 5.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus MelC1 PF06236.6 KOS18418.1 - 2.6 8.0 8.4 4 7.4 5.8 1.3 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 Period_C PF12114.3 KOS18418.1 - 3.5 7.1 10.0 4.5 6.8 6.9 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region RAP1 PF07218.6 KOS18418.1 - 3.9 5.4 10.7 4.1 5.3 7.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Herpes_capsid PF06112.6 KOS18418.1 - 5 7.1 17.9 6 6.8 12.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein AAA PF00004.24 KOS18419.1 - 1.3e-98 326.3 0.0 8.2e-48 161.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KOS18419.1 - 5.9e-19 67.8 1.1 1.6e-18 66.4 0.2 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 KOS18419.1 - 5.9e-14 51.6 0.0 3.3e-06 26.3 0.0 2.9 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KOS18419.1 - 6.1e-14 52.2 0.0 1.8e-07 31.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KOS18419.1 - 3.8e-13 49.3 0.5 9.2e-07 28.6 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KOS18419.1 - 1.1e-12 48.0 0.0 1.3e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KOS18419.1 - 4.4e-12 46.2 0.3 0.00067 19.8 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KOS18419.1 - 1.3e-11 44.8 0.0 0.00029 20.8 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KOS18419.1 - 6.2e-11 43.1 0.0 0.00043 21.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KOS18419.1 - 1.5e-09 37.5 3.7 0.0076 15.6 0.0 4.4 2 2 2 4 4 4 3 AAA domain TIP49 PF06068.8 KOS18419.1 - 2.9e-09 36.1 0.1 0.00086 18.1 0.0 2.6 2 1 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 KOS18419.1 - 2e-08 34.2 0.0 0.0014 18.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KOS18419.1 - 2.1e-08 33.4 0.1 0.011 14.8 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin IstB_IS21 PF01695.12 KOS18419.1 - 2.7e-08 33.4 0.2 0.0054 16.1 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KOS18419.1 - 1.6e-07 30.6 0.2 0.0056 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KOS18419.1 - 2.3e-07 30.4 4.8 0.0084 15.8 0.0 3.3 4 0 0 4 4 2 2 Part of AAA domain CDC48_2 PF02933.12 KOS18419.1 - 2.4e-07 30.2 0.3 2.5e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 KaiC PF06745.8 KOS18419.1 - 3.9e-07 29.4 0.6 0.22 10.5 0.0 3.5 2 1 1 3 3 3 2 KaiC RNA_helicase PF00910.17 KOS18419.1 - 5.4e-07 29.7 0.0 0.029 14.5 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_18 PF13238.1 KOS18419.1 - 1.6e-06 28.4 0.0 0.086 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KOS18419.1 - 1.9e-06 27.9 0.0 0.085 12.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.1 KOS18419.1 - 2.2e-06 27.4 0.0 0.095 12.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 KOS18419.1 - 2.6e-06 27.4 0.0 0.0021 17.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.8 KOS18419.1 - 4.1e-06 25.9 0.0 0.013 14.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 KOS18419.1 - 7.6e-06 24.9 0.0 0.044 12.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 KOS18419.1 - 8e-06 25.7 0.0 5.3 6.6 0.0 3.9 2 2 2 4 4 4 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 KOS18419.1 - 9.3e-06 25.7 0.0 0.044 13.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 KOS18419.1 - 1e-05 25.8 0.0 0.18 12.0 0.0 3.7 2 1 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.21 KOS18419.1 - 1.3e-05 24.7 0.1 0.16 11.4 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 KOS18419.1 - 1.4e-05 24.8 0.0 0.085 12.5 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Bac_DnaA PF00308.13 KOS18419.1 - 1.8e-05 24.4 0.0 0.12 11.9 0.0 3.0 3 0 0 3 3 3 2 Bacterial dnaA protein Vps4_C PF09336.5 KOS18419.1 - 3.5e-05 23.6 0.0 0.00021 21.1 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain PhoH PF02562.11 KOS18419.1 - 9.6e-05 21.7 0.2 0.43 9.7 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 KOS18419.1 - 0.00015 21.3 0.0 0.57 9.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KOS18419.1 - 0.00017 21.2 0.0 0.51 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 KOS18419.1 - 0.00034 20.2 0.0 0.63 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KOS18419.1 - 0.00055 18.8 0.1 0.59 8.9 0.0 2.7 3 0 0 3 3 2 2 NB-ARC domain NTPase_1 PF03266.10 KOS18419.1 - 0.00064 19.4 0.3 0.64 9.7 0.0 3.9 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.4 KOS18419.1 - 0.0015 17.6 0.0 1.5 7.7 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KOS18419.1 - 0.0064 16.0 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 KOS18419.1 - 0.0088 15.0 0.4 1 8.2 0.0 3.4 2 2 1 4 4 4 1 KAP family P-loop domain IPT PF01745.11 KOS18419.1 - 0.011 14.9 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 KOS18419.1 - 0.019 14.6 0.1 8.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zot PF05707.7 KOS18419.1 - 0.033 13.6 0.1 13 5.2 0.1 3.9 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 KOS18419.1 - 0.033 13.6 0.7 1.6 8.1 0.0 3.4 3 1 1 4 4 4 0 AAA-like domain AAA_23 PF13476.1 KOS18419.1 - 0.089 13.1 0.0 4.6 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 KOS18419.1 - 0.091 12.6 0.1 8.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AFG1_ATPase PF03969.11 KOS18419.1 - 0.091 11.5 0.0 12 4.6 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase KTI12 PF08433.5 KOS18419.1 - 0.12 11.5 0.0 11 5.1 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 MobB PF03205.9 KOS18419.1 - 0.16 11.6 1.8 3.5 7.3 0.0 3.5 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B TFIIS_M PF07500.9 KOS18420.1 - 3.7e-27 94.6 1.7 8.2e-27 93.5 1.1 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KOS18420.1 - 9.4e-19 66.7 7.1 1.4e-18 66.1 4.9 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KOS18420.1 - 1.4e-13 50.1 0.2 4.9e-13 48.3 0.1 2.0 1 1 1 2 2 2 1 TFIIS helical bundle-like domain DUF3006 PF11213.3 KOS18420.1 - 0.14 11.9 1.0 1.2 8.9 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3006) Evr1_Alr PF04777.8 KOS18420.1 - 0.29 11.0 3.3 1.3 8.9 1.1 2.5 1 1 1 2 2 2 0 Erv1 / Alr family XPG_N PF00752.12 KOS18421.1 - 2.7e-33 114.2 0.0 6.7e-33 112.9 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KOS18421.1 - 4e-25 87.6 0.0 9.8e-25 86.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 KOS18421.1 - 0.0078 15.7 0.0 0.021 14.3 0.0 1.7 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 KOS18421.1 - 0.048 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold zf-met2 PF12907.2 KOS18422.1 - 5e-16 58.3 4.0 7.3e-16 57.8 2.8 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 KOS18422.1 - 1.1e-08 35.5 10.9 1.8e-08 34.9 7.5 1.3 1 0 0 1 1 1 1 4F5 protein family zinc_ribbon_5 PF13719.1 KOS18422.1 - 0.017 14.7 5.0 0.21 11.2 0.3 1.5 1 1 1 2 2 1 0 zinc-ribbon domain HypA PF01155.14 KOS18422.1 - 0.042 13.5 0.3 0.042 13.5 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_4 PF13717.1 KOS18422.1 - 0.078 12.6 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DIOX_N PF14226.1 KOS18423.1 - 5.4e-29 101.0 0.0 8.1e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KOS18423.1 - 7.8e-13 48.5 0.0 1.3e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pro_isomerase PF00160.16 KOS18424.1 - 8.8e-49 165.6 0.2 9.8e-49 165.5 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pectate_lyase_3 PF12708.2 KOS18425.1 - 9.4e-34 117.4 10.4 5.7e-26 92.0 3.4 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein Beta_helix PF13229.1 KOS18425.1 - 3.6e-05 23.5 5.0 3.6e-05 23.5 3.4 2.7 2 0 0 2 2 2 1 Right handed beta helix region NosD PF05048.8 KOS18425.1 - 0.00033 19.8 1.1 0.00033 19.8 0.8 2.2 2 0 0 2 2 2 1 Periplasmic copper-binding protein (NosD) Bap31 PF05529.7 KOS18426.1 - 1.2e-59 200.9 2.8 2.5e-59 199.9 1.9 1.5 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like SET PF00856.23 KOS18426.1 - 5.9e-20 72.1 0.4 5.9e-20 72.1 0.3 3.3 3 1 0 3 3 3 1 SET domain RibD_C PF01872.12 KOS18427.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain HHH PF00633.18 KOS18427.1 - 0.053 13.2 0.5 0.14 11.9 0.3 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif LSM PF01423.17 KOS18428.1 - 1.4e-07 30.9 0.0 2.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KOS18428.1 - 0.024 14.5 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Pil1 PF13805.1 KOS18429.1 - 8.5e-153 507.1 0.3 1e-152 506.8 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 RRM_6 PF14259.1 KOS18430.1 - 0.0013 18.6 0.0 0.0031 17.4 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-Tim10_DDP PF02953.10 KOS18431.1 - 2.2e-22 78.0 3.1 2.6e-22 77.8 2.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KOS18431.1 - 0.0044 16.4 1.0 0.0049 16.3 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) bZIP_1 PF00170.16 KOS18431.1 - 0.042 13.7 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 bZIP transcription factor RL11D PF11088.3 KOS18431.1 - 0.09 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Pribosyltran PF00156.22 KOS18432.1 - 5.2e-16 58.5 0.0 7.3e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KOS18432.1 - 0.0041 16.3 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SKI PF01202.17 KOS18432.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase CLTH PF10607.4 KOS18433.1 - 6.7e-28 97.2 0.0 1.2e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KOS18433.1 - 1.7e-17 62.8 4.6 4.5e-17 61.4 3.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 KOS18433.1 - 7.2e-07 28.9 2.6 1.4e-06 27.9 1.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KOS18433.1 - 2.6e-06 27.0 2.5 4.8e-06 26.1 1.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Rtf2 PF04641.7 KOS18433.1 - 1.3e-05 24.5 0.4 1.3e-05 24.5 0.3 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 KOS18433.1 - 2.3e-05 23.9 4.9 5.7e-05 22.6 3.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS18433.1 - 4.4e-05 23.4 4.1 0.00011 22.1 2.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS18433.1 - 5.8e-05 22.6 1.9 0.00011 21.7 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KOS18433.1 - 0.002 17.9 4.2 0.0045 16.8 2.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KOS18433.1 - 0.083 12.4 2.5 0.18 11.4 1.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 KOS18433.1 - 0.12 11.9 1.1 0.31 10.6 0.8 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TFIIA PF03153.8 KOS18433.1 - 0.13 12.1 18.9 0.19 11.6 13.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-MIZ PF02891.15 KOS18433.1 - 0.16 11.4 3.3 0.32 10.5 2.3 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Cwf_Cwc_15 PF04889.7 KOS18433.1 - 0.72 9.5 14.4 1.2 8.7 10.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PG_binding_1 PF01471.13 KOS18434.1 - 0.0024 17.8 0.0 5.1 7.1 0.0 3.3 3 0 0 3 3 3 2 Putative peptidoglycan binding domain GATA PF00320.22 KOS18437.1 - 4.7e-16 57.8 4.9 9e-16 56.9 3.4 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 KOS18437.1 - 1.7e-12 47.2 0.0 3.3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 KOS18437.1 - 4.4e-08 33.4 0.0 9.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 KOS18437.1 - 5.9e-07 29.2 0.0 1.7e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 KOS18437.1 - 7.1e-06 26.0 0.0 2.4e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 KOS18437.1 - 4.5e-05 23.3 0.0 8.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 PAS domain TF_Zn_Ribbon PF08271.7 KOS18437.1 - 0.13 11.5 0.7 0.79 9.0 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.1 KOS18437.1 - 1.5 8.6 4.6 0.56 9.9 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Amidase PF01425.16 KOS18438.1 - 4.1e-58 197.2 0.1 5.4e-58 196.8 0.1 1.1 1 0 0 1 1 1 1 Amidase Glyco_hydro_47 PF01532.15 KOS18439.1 - 2.9e-130 434.9 0.0 5.8e-130 433.9 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 Pex14_N PF04695.8 KOS18439.1 - 0.091 12.8 7.3 0.077 13.0 2.2 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF775 PF05603.7 KOS18439.1 - 0.21 11.1 5.0 0.34 10.3 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Suf PF05843.9 KOS18439.1 - 0.21 11.2 8.4 0.35 10.5 5.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FimP PF09766.4 KOS18439.1 - 0.31 10.0 13.3 0.5 9.3 9.3 1.2 1 0 0 1 1 1 0 Fms-interacting protein PAT1 PF09770.4 KOS18439.1 - 0.71 8.0 20.7 1.1 7.4 14.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Myb_DNA-bind_3 PF12776.2 KOS18440.1 - 0.014 15.9 1.7 0.039 14.5 0.7 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain AIP3 PF03915.8 KOS18441.1 - 9.3e-151 502.5 12.7 9.3e-151 502.5 8.8 2.1 2 0 0 2 2 2 1 Actin interacting protein 3 FliL PF03748.9 KOS18441.1 - 0.0042 17.0 0.1 0.027 14.4 0.1 2.4 2 0 0 2 2 2 1 Flagellar basal body-associated protein FliL Lectin_N PF03954.9 KOS18441.1 - 0.008 15.5 0.1 0.008 15.5 0.1 2.7 3 0 0 3 3 3 1 Hepatic lectin, N-terminal domain NPV_P10 PF05531.7 KOS18441.1 - 0.012 15.8 5.5 0.18 12.0 0.0 3.8 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 KOS18441.1 - 0.054 13.2 8.4 0.13 12.0 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Desmo_N PF06771.6 KOS18441.1 - 0.084 12.8 0.1 0.34 10.8 0.1 2.1 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus COMP PF11598.3 KOS18441.1 - 0.85 9.7 4.4 9.8 6.3 0.0 3.8 4 0 0 4 4 4 0 Cartilage oligomeric matrix protein Syntaxin_2 PF14523.1 KOS18441.1 - 2.2 8.3 9.4 3.3 7.7 0.0 4.7 4 1 2 6 6 6 0 Syntaxin-like protein PAPA-1 PF04795.7 KOS18442.1 - 2.4e-25 89.0 3.0 2.4e-25 89.0 2.1 4.7 3 1 0 4 4 4 1 PAPA-1-like conserved region MFS_1 PF07690.11 KOS18443.1 - 5.7e-20 71.3 48.8 6.9e-20 71.0 30.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KOS18443.1 - 3.6e-10 38.6 24.7 5.4e-10 38.1 17.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KOS18443.1 - 0.0068 16.1 4.4 0.051 13.3 0.2 3.7 3 0 0 3 3 3 1 MFS_1 like family Ras PF00071.17 KOS18444.1 - 1.5e-63 212.9 0.2 1.8e-63 212.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS18444.1 - 1.9e-21 76.7 0.1 2.7e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS18444.1 - 2.7e-13 49.5 0.1 3.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KOS18444.1 - 2.9e-08 33.6 0.1 4.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KOS18444.1 - 2.8e-05 23.6 0.1 9.6e-05 21.8 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KOS18444.1 - 6.5e-05 22.1 0.1 0.00011 21.4 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KOS18444.1 - 0.00012 22.2 0.1 0.00033 20.8 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KOS18444.1 - 0.0012 18.7 0.1 0.0031 17.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KOS18444.1 - 0.0016 17.5 0.0 0.0019 17.3 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KOS18444.1 - 0.0028 16.8 0.1 0.0063 15.7 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 KOS18444.1 - 0.0062 16.4 0.1 0.082 12.8 0.0 2.1 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 KOS18444.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KOS18444.1 - 0.017 15.3 0.1 0.024 14.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 KOS18444.1 - 0.019 14.5 0.1 0.051 13.1 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 KOS18444.1 - 0.021 14.8 0.4 0.043 13.7 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 KOS18444.1 - 0.08 12.2 0.1 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 KOS18444.1 - 0.088 12.3 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_32 PF13654.1 KOS18444.1 - 0.095 11.3 0.1 0.62 8.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.9 KOS18444.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pex14_N PF04695.8 KOS18445.1 - 7.4e-19 68.1 0.0 7.4e-19 68.1 0.0 2.9 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region BAF1_ABF1 PF04684.8 KOS18445.1 - 0.11 11.3 16.5 0.16 10.7 11.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4407 PF14362.1 KOS18445.1 - 9.1 5.1 6.9 68 2.2 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Brix PF04427.13 KOS18447.1 - 3.2e-38 131.2 0.0 4.1e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Brix domain Hist_deacetyl PF00850.14 KOS18449.1 - 1.5e-89 300.3 0.0 2.3e-89 299.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KOS18449.1 - 7.1e-42 142.8 0.3 1e-41 142.2 0.2 1.2 1 0 0 1 1 1 1 Arb2 domain Fungal_trans PF04082.13 KOS18451.1 - 2.5e-28 98.6 0.0 4e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain efThoc1 PF11957.3 KOS18451.1 - 0.034 12.6 0.0 0.061 11.8 0.0 1.3 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor Macoilin PF09726.4 KOS18452.1 - 1.8 6.7 4.8 1.9 6.6 3.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Menin PF05053.8 KOS18452.1 - 2.3 6.2 6.0 2.3 6.2 4.2 1.1 1 0 0 1 1 1 0 Menin Peptidase_C48 PF02902.14 KOS18453.1 - 5.1e-24 85.1 0.0 7.4e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GTP_EFTU PF00009.22 KOS18454.1 - 2.3e-60 203.2 0.2 3.1e-60 202.8 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KOS18454.1 - 6.9e-27 93.5 0.0 1.6e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KOS18454.1 - 1.2e-17 63.7 2.4 1.1e-16 60.7 1.5 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KOS18454.1 - 6.2e-06 26.1 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KOS18454.1 - 0.00012 21.6 0.5 0.002 17.6 0.2 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Miro PF08477.8 KOS18454.1 - 0.001 19.5 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KOS18454.1 - 0.081 12.4 0.2 8.2 5.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 KOS18454.1 - 0.089 11.9 0.1 0.27 10.3 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Proteasome PF00227.21 KOS18455.1 - 5.5e-38 130.1 0.0 6.4e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 KOS18456.1 - 1.1e-28 98.0 4.7 1.1e-08 34.6 0.0 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 KOS18456.1 - 0.00024 19.3 0.1 0.12 10.4 0.1 2.6 2 1 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KOS18456.1 - 0.027 14.7 0.5 0.52 10.6 0.1 3.1 2 0 0 2 2 2 0 PQQ-like domain Apc1 PF12859.2 KOS18456.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 AMP-binding PF00501.23 KOS18457.1 - 3.8e-07 28.8 0.2 4.5e-06 25.3 0.0 2.1 2 1 0 2 2 2 2 AMP-binding enzyme DEAD PF00270.24 KOS18458.1 - 1.4e-45 154.8 0.0 2.9e-44 150.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS18458.1 - 3.9e-28 97.1 0.1 7.3e-28 96.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS18458.1 - 0.039 13.7 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Ribosomal_S28e PF01200.13 KOS18458.1 - 0.068 12.9 0.1 0.47 10.2 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S28e DUF1253 PF06862.7 KOS18458.1 - 0.13 10.6 0.0 0.23 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 KOS18458.1 - 0.17 10.8 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Abhydrolase_5 PF12695.2 KOS18459.1 - 1.4e-05 24.9 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KOS18459.1 - 2.2e-05 24.1 0.0 4.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KOS18459.1 - 2.9e-05 24.0 3.0 2.9e-05 24.0 2.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 KOS18459.1 - 3.5e-05 23.2 0.0 5.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) CAF-1_p150 PF11600.3 KOS18459.1 - 0.00051 19.4 25.3 0.0011 18.4 17.5 1.5 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Abhydrolase_1 PF00561.15 KOS18459.1 - 0.0072 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 KOS18459.1 - 0.0092 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 KOS18459.1 - 0.037 13.6 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 KOS18459.1 - 0.069 13.3 2.9 0.082 13.1 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain Macoilin PF09726.4 KOS18459.1 - 0.19 10.0 7.1 0.31 9.2 4.9 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF883 PF05957.8 KOS18459.1 - 8 6.9 15.3 14 6.1 10.1 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) HET PF06985.6 KOS18460.1 - 1.4e-14 54.4 0.0 2.3e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nucleoplasmin PF03066.10 KOS18460.1 - 0.18 11.3 5.1 0.35 10.3 3.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 KOS18460.1 - 0.26 10.8 6.4 0.45 10.0 4.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 KOS18460.1 - 0.66 9.7 3.2 1.3 8.8 2.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.5 KOS18460.1 - 3.8 7.7 13.6 0.25 11.6 4.7 2.5 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Mito_carr PF00153.22 KOS18461.1 - 8.3e-47 156.8 4.3 3.4e-16 58.7 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3337 PF11816.3 KOS18462.1 - 3.2e-85 286.4 0.0 3.1e-81 273.3 0.0 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3337) WD40 PF00400.27 KOS18462.1 - 7.6e-26 89.0 12.3 5.9e-06 25.9 0.3 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat KH_1 PF00013.24 KOS18463.1 - 1.5e-42 143.0 12.1 9.8e-16 57.1 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KOS18463.1 - 7.7e-32 108.3 16.2 1.2e-10 40.7 1.2 4.1 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 KOS18463.1 - 7.6e-13 47.8 2.4 0.0083 15.6 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KOS18463.1 - 4.9e-08 32.5 5.5 0.13 11.9 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KOS18463.1 - 9e-06 25.4 3.2 0.033 13.9 0.0 3.5 4 0 0 4 4 4 2 NusA-like KH domain SLS PF14611.1 KOS18463.1 - 0.14 11.5 0.0 3.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator 6PF2K PF01591.13 KOS18464.1 - 5e-78 261.2 0.0 6.8e-78 260.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KOS18464.1 - 3.5e-31 108.4 0.0 7.2e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KOS18464.1 - 1.4e-09 37.9 0.0 2.5e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KOS18464.1 - 0.00013 21.2 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KOS18464.1 - 0.00021 22.1 0.2 0.037 14.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain Methyltransf_26 PF13659.1 KOS18464.1 - 0.034 14.1 0.1 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Zeta_toxin PF06414.7 KOS18464.1 - 0.13 11.2 0.1 0.54 9.3 0.0 2.1 3 0 0 3 3 3 0 Zeta toxin Flavin_Reduct PF01613.13 KOS18465.1 - 5e-21 75.1 0.1 7.4e-21 74.6 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 KOS18465.1 - 0.066 12.7 0.0 0.1 12.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF447) PDEase_II PF02112.10 KOS18466.1 - 2e-54 184.7 0.0 5e-21 74.9 0.0 3.8 3 1 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 KOS18466.1 - 0.0032 17.0 0.0 0.021 14.3 0.0 2.2 2 1 0 2 2 2 1 Beta-lactamase superfamily domain DEAD PF00270.24 KOS18467.1 - 7.5e-43 145.9 1.3 8.7e-43 145.7 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS18467.1 - 5.4e-25 87.0 0.0 1.2e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KOS18467.1 - 0.00014 20.4 1.4 0.0022 16.4 0.0 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF1253) EB1 PF03271.12 KOS18468.1 - 1.5e-16 60.1 0.7 2.7e-16 59.2 0.5 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 KOS18468.1 - 1.3e-06 28.4 0.5 1.8e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain PX PF00787.19 KOS18469.1 - 1.8e-15 56.7 0.0 2.9e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 KOS18469.1 - 1.9e-13 49.8 6.0 5.1e-13 48.5 4.1 1.8 1 0 0 1 1 1 1 SNARE domain DUF3275 PF11679.3 KOS18469.1 - 0.097 12.2 2.5 0.19 11.3 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF16 PF01519.11 KOS18469.1 - 3.9 7.7 5.9 9.3 6.5 4.1 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 FliJ PF02050.11 KOS18469.1 - 4.3 7.4 16.0 1.5 8.8 5.3 2.8 3 0 0 3 3 3 0 Flagellar FliJ protein Ribosomal_60s PF00428.14 KOS18469.1 - 4.6 7.6 16.8 7.8 6.9 5.3 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein WD40 PF00400.27 KOS18471.1 - 5.5e-46 152.8 14.6 2e-09 36.9 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KOS18471.1 - 1.3e-08 34.4 0.1 2.7e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS18471.1 - 2.3e-08 33.4 0.0 4.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KOS18471.1 - 4.1e-07 28.5 1.6 0.094 10.8 0.0 4.3 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KOS18471.1 - 0.0023 16.3 0.1 0.0088 14.3 0.0 1.9 2 0 0 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KOS18471.1 - 0.011 14.5 0.4 0.48 9.1 0.1 2.7 2 1 0 2 2 2 0 Nup133 N terminal like PQQ_2 PF13360.1 KOS18471.1 - 0.014 14.9 0.1 0.058 12.8 0.1 1.9 1 1 0 1 1 1 0 PQQ-like domain FlaG PF03646.10 KOS18471.1 - 0.031 14.3 0.0 1.4 9.1 0.0 3.0 3 0 0 3 3 3 0 FlaG protein Pectate_lyase_3 PF12708.2 KOS18472.1 - 2.3e-78 263.4 33.6 5e-68 229.5 6.8 3.8 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KOS18472.1 - 9.3e-07 28.2 1.2 0.015 14.7 0.2 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Lactamase_B_2 PF12706.2 KOS18474.1 - 8.4e-29 100.4 0.0 1.7e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KOS18474.1 - 1.9e-20 72.0 0.1 2.1e-19 68.7 0.0 2.5 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B PF00753.22 KOS18474.1 - 8.2e-10 38.6 0.2 2e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily LIM_bind PF01803.11 KOS18475.1 - 1.6e-75 253.3 0.0 1.6e-75 253.3 0.0 3.6 4 0 0 4 4 4 1 LIM-domain binding protein HbrB PF08539.6 KOS18476.1 - 8.4e-51 171.9 0.0 1.2e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 HbrB-like Gon7 PF08738.5 KOS18478.1 - 8.2e-12 45.0 0.0 9.5e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Gon7 family RNA_pol_3_Rpc31 PF11705.3 KOS18478.1 - 0.016 15.1 1.7 0.018 14.9 1.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NUDE_C PF04880.8 KOS18478.1 - 0.35 11.2 3.8 0.39 11.0 2.6 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region PALP PF00291.20 KOS18480.1 - 3.3e-59 200.6 0.0 3.7e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme WSC PF01822.14 KOS18481.1 - 1e-48 163.1 39.8 2.2e-16 59.5 3.9 3.7 3 0 0 3 3 3 3 WSC domain CENP-S PF15630.1 KOS18481.1 - 1.7e-34 117.8 0.0 2.9e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S peroxidase PF00141.18 KOS18481.1 - 8.3e-20 71.2 0.0 2e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Peroxidase Bromo_TP PF07524.8 KOS18481.1 - 0.00075 19.1 0.0 0.0021 17.7 0.0 1.8 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 KOS18481.1 - 0.026 13.7 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 KOS18481.1 - 0.31 11.2 0.0 0.57 10.3 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 PALP PF00291.20 KOS18482.1 - 1.3e-54 185.5 0.5 1.6e-54 185.2 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3384 PF11864.3 KOS18483.1 - 9.6e-86 288.0 0.0 2.1e-85 286.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 KOS18483.1 - 1.1e-56 191.1 0.0 1.9e-56 190.4 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 KOS18483.1 - 2.7e-32 112.2 0.0 1.4e-28 100.0 0.0 2.9 3 0 0 3 3 3 2 Tuberin CENP-I PF07778.6 KOS18484.1 - 3.7e-86 289.3 0.0 4.5e-69 233.0 0.0 2.1 1 1 1 2 2 2 2 Mis6 ABC_tran PF00005.22 KOS18485.1 - 3e-13 50.2 0.1 6.8e-12 45.8 0.0 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KOS18485.1 - 3.4e-10 40.3 0.1 0.00025 21.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain DUF3584 PF12128.3 KOS18485.1 - 0.00027 18.4 0.4 0.00036 18.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_15 PF13175.1 KOS18485.1 - 0.0003 19.9 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KOS18485.1 - 0.00049 19.5 0.1 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SRP54 PF00448.17 KOS18485.1 - 0.002 17.5 0.1 0.0045 16.4 0.0 1.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SMC_N PF02463.14 KOS18485.1 - 0.0046 16.2 0.0 2.8 7.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KOS18485.1 - 0.0055 17.0 0.0 0.0083 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KOS18485.1 - 0.0077 15.6 0.5 0.024 14.0 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS18485.1 - 0.0092 16.7 0.6 0.025 15.3 0.4 1.9 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KOS18485.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 KOS18485.1 - 0.013 15.7 0.1 0.12 12.5 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KOS18485.1 - 0.013 15.4 1.1 0.074 13.0 0.8 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 KOS18485.1 - 0.015 14.7 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.1 KOS18485.1 - 0.016 15.1 0.2 0.037 14.0 0.2 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KOS18485.1 - 0.028 13.9 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 KOS18485.1 - 0.035 14.2 0.4 0.17 12.0 0.2 2.2 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 KOS18485.1 - 0.042 13.7 0.1 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KOS18485.1 - 0.057 12.6 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_13 PF13166.1 KOS18485.1 - 0.068 11.6 0.0 0.089 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 KOS18485.1 - 0.075 12.2 0.3 0.17 11.0 0.2 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family NACHT PF05729.7 KOS18485.1 - 0.14 11.7 0.2 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 KOS18485.1 - 0.2 11.0 0.3 0.31 10.4 0.2 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DNA_pol_E_B PF04042.11 KOS18486.1 - 5.7e-50 169.4 0.0 7.6e-50 169.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PPP4R2 PF09184.6 KOS18487.1 - 0.82 9.1 10.0 17 4.8 0.0 2.3 2 0 0 2 2 2 0 PPP4R2 FAM196 PF15265.1 KOS18487.1 - 2.9 7.0 8.6 6 5.9 6.0 1.5 1 0 0 1 1 1 0 FAM196 family CAS_CSE1 PF03378.10 KOS18488.1 - 1.2e-158 528.0 0.1 6.5e-158 525.5 0.0 2.0 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KOS18488.1 - 6.7e-146 485.5 2.7 9.7e-146 485.0 1.8 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 KOS18488.1 - 3.1e-13 49.4 0.1 1.6e-12 47.1 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KOS18488.1 - 0.0063 16.4 1.3 2.1 8.2 0.0 4.0 4 1 0 4 4 4 1 Exportin 1-like protein V-ATPase_H_N PF03224.9 KOS18488.1 - 0.014 14.5 0.6 0.2 10.7 0.0 3.0 2 1 1 4 4 4 0 V-ATPase subunit H UCH PF00443.24 KOS18489.1 - 3.4e-42 144.4 0.0 2e-35 122.1 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS18489.1 - 3.6e-12 46.3 0.0 2.2e-08 33.8 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase hNIFK_binding PF12196.3 KOS18489.1 - 0.64 9.4 4.3 1 8.7 0.0 2.6 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK F-box-like PF12937.2 KOS18490.1 - 0.054 13.2 0.2 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 F-box-like Myc_N PF01056.13 KOS18490.1 - 5.7 6.0 8.2 0.87 8.6 2.4 1.8 2 0 0 2 2 2 0 Myc amino-terminal region ATG11 PF10377.4 KOS18491.1 - 2e-39 134.4 0.2 2e-39 134.4 0.1 3.9 4 0 0 4 4 4 1 Autophagy-related protein 11 MscS_porin PF12795.2 KOS18491.1 - 0.00039 19.8 13.8 0.00039 19.8 9.5 6.4 3 1 2 6 6 6 2 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.7 KOS18491.1 - 0.26 11.0 73.0 0.05 13.3 15.9 7.1 6 3 1 7 7 7 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KOS18491.1 - 3.5 6.7 23.5 0.017 14.3 2.6 4.3 5 0 0 5 5 5 0 Reovirus sigma C capsid protein CENP-H PF05837.7 KOS18492.1 - 1.4e-26 92.7 0.0 1e-23 83.5 0.0 2.2 2 0 0 2 2 2 2 Centromere protein H (CENP-H) VIT1 PF01988.14 KOS18494.1 - 6.1e-39 133.7 0.0 2.8e-18 66.2 0.0 2.1 2 0 0 2 2 2 2 VIT family RXT2_N PF08595.6 KOS18494.1 - 0.16 11.7 0.1 0.27 11.0 0.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Phosphoesterase PF04185.9 KOS18495.1 - 1.8e-24 86.6 1.9 1.5e-20 73.8 1.4 2.2 2 0 0 2 2 2 2 Phosphoesterase family Med3 PF11593.3 KOS18495.1 - 0.22 10.7 12.6 0.31 10.2 8.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CW_binding_1 PF01473.15 KOS18496.1 - 0.047 13.8 1.0 0.094 12.8 0.7 1.5 1 0 0 1 1 1 0 Putative cell wall binding repeat DUF3802 PF12290.3 KOS18496.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) FAD_binding_3 PF01494.14 KOS18497.1 - 1.4e-19 70.3 0.2 8.7e-18 64.4 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KOS18497.1 - 3.3e-06 26.2 0.0 0.048 12.5 0.1 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KOS18497.1 - 0.0006 18.8 1.0 0.0026 16.7 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KOS18497.1 - 0.0081 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KOS18497.1 - 0.013 15.4 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS18497.1 - 0.022 14.7 0.0 0.22 11.5 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KOS18497.1 - 0.023 13.8 0.0 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Thi4 family SE PF08491.5 KOS18497.1 - 0.042 12.6 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase K_oxygenase PF13434.1 KOS18497.1 - 0.046 12.6 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 KOS18497.1 - 0.063 11.8 0.0 0.93 8.0 0.0 2.3 2 1 0 2 2 2 0 Tryptophan halogenase Complex1_49kDa PF00346.14 KOS18498.1 - 2.4e-134 446.5 0.0 3e-134 446.2 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 KOS18498.1 - 0.13 10.9 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Pyr_redox_2 PF07992.9 KOS18499.1 - 3.2e-29 102.2 0.3 3.7e-29 102.0 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS18499.1 - 1.7e-16 60.3 1.2 9.6e-14 51.5 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KOS18499.1 - 1.6e-09 38.1 0.0 8e-07 29.3 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KOS18499.1 - 2.2e-07 30.1 1.5 0.056 12.3 0.0 3.4 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KOS18499.1 - 6.9e-05 23.0 0.0 0.033 14.4 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 KOS18499.1 - 0.00045 19.3 0.3 0.0014 17.8 0.0 1.9 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 KOS18499.1 - 0.00049 19.0 4.7 0.028 13.2 0.2 3.6 3 1 1 4 4 4 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KOS18499.1 - 0.00065 18.8 0.1 0.007 15.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KOS18499.1 - 0.0027 16.5 6.3 0.032 13.0 0.2 3.2 2 1 2 4 4 4 1 FAD binding domain Shikimate_DH PF01488.15 KOS18499.1 - 0.0035 17.4 0.5 2.5 8.1 0.0 2.6 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KOS18499.1 - 0.0036 17.2 0.4 0.028 14.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KOS18499.1 - 0.01 14.3 0.1 0.8 8.1 0.1 2.6 2 1 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.1 KOS18499.1 - 0.055 13.2 0.1 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Vps53_N PF04100.7 KOS18500.1 - 1.8e-102 342.9 0.0 2.7e-102 342.4 0.0 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 KOS18500.1 - 0.00038 19.4 3.7 0.00063 18.7 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 KOS18500.1 - 0.015 13.4 3.0 0.03 12.5 2.1 1.4 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 V-ATPase_H_C PF11698.3 KOS18500.1 - 0.055 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 V-ATPase subunit H Spc7 PF08317.6 KOS18500.1 - 0.18 10.4 2.8 0.29 9.7 1.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Peptidase_M16 PF00675.15 KOS18501.1 - 3.4e-56 189.1 0.3 8e-56 187.9 0.2 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KOS18501.1 - 9.2e-41 139.5 0.0 1.8e-40 138.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain TFIID-31kDa PF02291.10 KOS18502.1 - 3.2e-27 94.8 0.0 2.5e-12 46.6 0.0 2.1 2 0 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit Histidinol_dh PF00815.15 KOS18503.1 - 7.6e-177 588.0 4.5 1.1e-176 587.5 3.1 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KOS18503.1 - 7.4e-24 83.1 0.0 1.3e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KOS18503.1 - 7.1e-11 42.2 0.1 7.1e-11 42.2 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase LNS2 PF08235.8 KOS18504.1 - 8.2e-70 233.4 0.0 1.4e-69 232.6 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KOS18504.1 - 3.2e-40 136.2 0.1 1.2e-39 134.3 0.0 2.0 3 0 0 3 3 3 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 KOS18504.1 - 0.0027 17.1 0.0 0.14 11.5 0.0 2.6 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) TFIIA PF03153.8 KOS18504.1 - 0.23 11.2 7.1 0.08 12.8 2.7 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-RING_2 PF13639.1 KOS18505.1 - 4.9e-13 48.6 6.9 7.3e-13 48.1 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KOS18505.1 - 1.4e-07 31.0 4.0 2.1e-07 30.4 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KOS18505.1 - 3.2e-07 30.3 6.1 7.5e-07 29.1 4.3 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KOS18505.1 - 1.2e-05 24.8 4.1 1.8e-05 24.3 2.8 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KOS18505.1 - 2.2e-05 24.0 2.7 3.2e-05 23.5 1.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS18505.1 - 5.5e-05 23.1 5.9 8e-05 22.5 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KOS18505.1 - 0.00069 19.3 1.9 0.0013 18.5 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KOS18505.1 - 0.0057 16.2 6.6 0.0089 15.5 4.6 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PHD PF00628.24 KOS18505.1 - 0.14 11.9 5.8 0.24 11.1 4.0 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 KOS18505.1 - 0.15 11.9 2.7 0.35 10.7 1.9 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 KOS18505.1 - 0.2 11.3 1.3 0.29 10.8 0.9 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_1 PF14446.1 KOS18505.1 - 0.25 11.0 8.7 1.9 8.3 6.0 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 KOS18505.1 - 1.3 8.9 5.2 4.3 7.3 3.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KOS18505.1 - 1.7 8.7 5.5 3.5 7.7 3.8 1.6 1 0 0 1 1 1 0 RING-variant domain DUF3752 PF12572.3 KOS18506.1 - 1.4e-35 122.6 1.8 2.3e-35 121.9 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) UDG PF03167.14 KOS18507.1 - 2.1e-21 75.9 0.0 2.6e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily UDPGP PF01704.13 KOS18508.1 - 5.1e-53 180.0 0.0 6.8e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Zip PF02535.17 KOS18510.1 - 1.8e-34 119.1 1.2 5.2e-34 117.6 0.8 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Sec63 PF02889.11 KOS18511.1 - 1.4e-44 152.5 0.0 5.3e-44 150.7 0.0 1.8 2 0 0 2 2 2 1 Sec63 Brl domain DnaJ PF00226.26 KOS18511.1 - 1.1e-16 60.3 0.5 2.5e-16 59.1 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain DUF3336 PF11815.3 KOS18512.1 - 1.3e-49 167.4 3.1 2.2e-49 166.6 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KOS18512.1 - 1.5e-20 74.0 0.6 3.6e-20 72.7 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase DUF3586 PF12131.3 KOS18513.1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3586) Esterase PF00756.15 KOS18514.1 - 1.1e-49 169.1 0.0 1.3e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KOS18514.1 - 6.4e-07 29.2 0.1 1e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS18514.1 - 3.3e-06 27.1 0.8 4.8e-06 26.6 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KOS18514.1 - 5.6e-06 25.7 0.1 1.3e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 KOS18514.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KOS18514.1 - 0.014 14.6 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 KOS18514.1 - 0.016 14.0 0.0 0.04 12.7 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme PGAP1 PF07819.8 KOS18514.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein zf-C2H2 PF00096.21 KOS18515.1 - 3.5e-30 102.5 47.1 0.00033 20.8 0.8 10.6 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS18515.1 - 4.7e-28 95.4 45.4 0.00052 20.1 0.1 10.5 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KOS18515.1 - 5.6e-16 57.9 57.8 0.0004 20.5 1.2 10.8 12 1 0 12 12 11 5 Zinc-finger double domain zf-Di19 PF05605.7 KOS18515.1 - 3.1e-05 23.9 34.4 0.53 10.4 1.3 7.5 4 2 3 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KOS18515.1 - 0.0002 21.4 26.2 1.6 8.9 0.9 7.9 7 1 0 7 7 7 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS18515.1 - 0.0031 17.6 15.9 2.9 8.2 0.1 7.0 7 0 0 7 7 7 1 Zinc-finger of C2H2 type IBR PF01485.16 KOS18515.1 - 0.017 14.9 0.9 0.017 14.9 0.6 5.7 2 2 1 3 3 2 0 IBR domain FYDLN_acid PF09538.5 KOS18515.1 - 0.017 15.6 1.8 0.017 15.6 1.2 3.7 4 0 0 4 4 3 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_4 PF13717.1 KOS18515.1 - 0.23 11.1 4.8 4.8 6.9 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KOS18515.1 - 0.28 10.7 4.8 4.7 6.8 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KOS18515.1 - 2.2 8.3 12.5 12 5.9 0.0 4.8 4 1 1 5 5 5 0 Zinc ribbon domain zf-C2H2_2 PF12756.2 KOS18515.1 - 3.4 7.8 26.4 0.23 11.5 0.4 5.6 5 2 1 6 6 5 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS1 PF03811.8 KOS18515.1 - 6.1 6.4 14.9 0.86 9.1 0.8 4.0 4 0 0 4 4 3 0 InsA N-terminal domain Rep_fac-A_C PF08646.5 KOS18515.1 - 7.8 6.1 8.2 0.82 9.3 0.2 3.0 3 1 1 4 4 3 0 Replication factor-A C terminal domain RPAP2_Rtr1 PF04181.8 KOS18515.1 - 8.1 6.6 11.1 1.6e+02 2.4 5.5 3.2 2 1 0 2 2 2 0 Rtr1/RPAP2 family RNA_pol_Rpb6 PF01192.17 KOS18516.1 - 5.9e-24 83.5 0.3 5.9e-24 83.5 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb6 Afi1 PF07792.7 KOS18517.1 - 3.7e-62 208.6 0.0 6.6e-62 207.8 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 KOS18517.1 - 4.8e-37 126.1 0.0 9.2e-37 125.2 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KOS18517.1 - 1.3e-08 33.7 0.1 0.023 13.1 0.0 4.0 3 1 1 4 4 4 3 Transport protein Avl9 Astro_capsid PF03115.9 KOS18517.1 - 0.021 13.1 0.1 0.031 12.5 0.1 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF2347 PF09804.4 KOS18517.1 - 0.059 12.6 0.0 0.37 10.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) EF-hand_6 PF13405.1 KOS18518.1 - 1.2e-12 46.5 0.0 2e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KOS18518.1 - 4.4e-10 38.1 0.9 0.0006 18.9 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KOS18518.1 - 6e-08 32.7 0.0 3.1e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KOS18518.1 - 1.6e-07 30.3 2.5 0.002 17.4 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KOS18518.1 - 3e-07 29.9 0.1 0.025 14.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair Med3 PF11593.3 KOS18518.1 - 0.097 11.8 12.4 0.11 11.7 8.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ebola_NP PF05505.7 KOS18518.1 - 0.45 8.5 2.6 0.58 8.1 1.8 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein MCPVI PF02993.9 KOS18518.1 - 1 9.4 10.2 1.5 8.9 6.5 1.6 2 0 0 2 2 2 0 Minor capsid protein VI TFIIA PF03153.8 KOS18518.1 - 1.1 9.0 8.6 1.4 8.7 6.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.5 KOS18518.1 - 2.5 6.3 7.6 3.3 6.0 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Methyltransf_18 PF12847.2 KOS18519.1 - 8.6e-18 64.9 0.0 1.4e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS18519.1 - 9.5e-15 54.4 0.0 1.5e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KOS18519.1 - 3.4e-09 36.7 0.1 5.6e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS18519.1 - 5.2e-08 33.2 0.0 1.4e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS18519.1 - 1.2e-07 31.6 0.0 1.1e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS18519.1 - 2.7e-05 24.4 0.0 6.1e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS18519.1 - 4.5e-05 23.8 0.1 0.00016 22.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain AdoMet_MTase PF07757.8 KOS18519.1 - 0.00048 20.2 0.0 0.00088 19.3 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_4 PF02390.12 KOS18519.1 - 0.0013 17.7 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 KOS18519.1 - 0.0017 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS18519.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 KOS18519.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 KOS18519.1 - 0.017 14.2 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KOS18519.1 - 0.074 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Nop14 PF04147.7 KOS18519.1 - 0.079 10.8 0.9 0.085 10.7 0.6 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KOS18519.1 - 0.088 12.3 5.3 0.13 11.7 3.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin CobT PF06213.7 KOS18519.1 - 0.097 11.7 4.7 0.16 11.0 3.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 KOS18519.1 - 0.9 9.1 5.0 1.7 8.2 3.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 KOS18519.1 - 1.3 6.9 3.6 1.7 6.5 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 KOS18519.1 - 1.9 8.8 10.3 0.12 12.7 3.5 1.7 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 KOS18519.1 - 2.6 7.2 6.2 3.9 6.6 4.3 1.2 1 0 0 1 1 1 0 NOA36 protein TFIIF_alpha PF05793.7 KOS18519.1 - 3 6.1 8.1 4.6 5.4 5.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-B_dimeris PF09026.5 KOS18519.1 - 3.6 7.8 10.6 7.6 6.8 7.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ADH_zinc_N PF00107.21 KOS18520.1 - 1.2e-23 83.0 0.2 1.5e-23 82.7 0.2 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KOS18520.1 - 2.6e-13 50.9 0.0 3.8e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KOS18520.1 - 0.0077 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SIS_2 PF13580.1 KOS18520.1 - 0.11 12.2 0.2 0.73 9.5 0.1 2.2 1 1 0 1 1 1 0 SIS domain DUF2441 PF10386.4 KOS18521.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) efThoc1 PF11957.3 KOS18522.1 - 3.4e-147 490.9 0.0 2.6e-146 487.9 0.0 1.9 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 KOS18522.1 - 1.8e-19 69.8 0.0 2.1e-18 66.4 0.0 2.2 1 1 1 2 2 2 1 Guanylate kinase Fer2_3 PF13085.1 KOS18523.1 - 7.6e-33 112.6 0.0 1.3e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.1 KOS18523.1 - 2.1e-09 37.2 4.3 2.1e-09 37.2 3.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 KOS18523.1 - 3e-09 37.0 6.1 3e-09 37.0 4.2 2.3 3 0 0 3 3 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KOS18523.1 - 2.5e-05 23.9 4.1 2.5e-05 23.9 2.9 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KOS18523.1 - 7.6e-05 22.8 4.9 0.025 14.8 0.6 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 KOS18523.1 - 0.00015 22.1 1.5 0.00015 22.1 1.1 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.22 KOS18523.1 - 0.0012 18.4 3.3 0.0019 17.8 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 KOS18523.1 - 0.0055 17.0 5.5 0.0055 17.0 3.8 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.3 KOS18523.1 - 0.19 12.1 1.8 0.83 10.0 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_15 PF13459.1 KOS18523.1 - 3.8 8.1 6.8 1.3 9.6 0.1 2.7 3 0 0 3 3 2 0 4Fe-4S single cluster domain Fer4_2 PF12797.2 KOS18523.1 - 4.3 7.4 17.8 1.7 8.7 3.1 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain AAA_12 PF13087.1 KOS18524.1 - 8e-29 100.4 0.0 1.4e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KOS18524.1 - 2.1e-22 79.8 0.0 7.2e-22 78.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS18524.1 - 2.7e-09 36.6 3.5 7.9e-08 31.9 0.0 3.4 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KOS18524.1 - 4.9e-06 26.2 0.3 0.0041 16.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain ResIII PF04851.10 KOS18524.1 - 0.00028 20.7 0.0 0.00055 19.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.24 KOS18524.1 - 0.0015 18.7 0.1 0.007 16.5 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KOS18524.1 - 0.0022 17.4 0.0 0.0064 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KOS18524.1 - 0.0025 17.9 0.0 0.023 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KOS18524.1 - 0.013 15.0 0.1 3.8 6.9 0.0 3.5 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KOS18524.1 - 0.021 14.3 1.4 0.034 13.6 0.0 2.1 3 0 0 3 3 2 0 DEAD/DEAH box helicase AAA_16 PF13191.1 KOS18524.1 - 0.023 14.6 0.0 0.089 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 KOS18524.1 - 0.032 13.2 0.0 0.077 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 KOS18524.1 - 0.037 13.1 0.0 0.037 13.1 0.0 1.9 2 0 0 2 2 1 0 Zeta toxin AAA_17 PF13207.1 KOS18524.1 - 0.043 14.6 0.7 1.4 9.7 0.0 3.7 4 0 0 4 4 4 0 AAA domain Arch_ATPase PF01637.13 KOS18524.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 KOS18524.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 KOS18524.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DnaB_C PF03796.10 KOS18524.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.17 KOS18524.1 - 0.13 12.4 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase UvrD-helicase PF00580.16 KOS18524.1 - 1 8.5 3.6 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain MBOAT PF03062.14 KOS18525.1 - 1.3e-20 73.7 16.8 1.3e-20 73.7 11.6 2.0 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ctr PF04145.10 KOS18525.1 - 0.00064 19.7 0.5 0.077 13.0 0.0 3.8 4 0 0 4 4 4 1 Ctr copper transporter family MBOAT_2 PF13813.1 KOS18525.1 - 0.0011 18.9 2.9 0.0039 17.2 2.0 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family OSTbeta PF15048.1 KOS18525.1 - 0.054 13.5 0.3 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF912 PF06024.7 KOS18525.1 - 0.062 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) LTV PF04180.9 KOS18526.1 - 4.1e-102 342.8 7.4 4.9e-102 342.5 5.1 1.0 1 0 0 1 1 1 1 Low temperature viability protein SBDS_C PF09377.5 KOS18527.1 - 1.6e-48 163.5 0.0 2.3e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KOS18527.1 - 1.9e-30 104.4 0.1 3.2e-30 103.7 0.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF3439 PF11921.3 KOS18527.1 - 0.0044 16.7 15.0 0.0089 15.7 10.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Med13_C PF06333.7 KOS18527.1 - 0.032 12.7 0.1 0.043 12.3 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Ribosomal_S13 PF00416.17 KOS18528.1 - 6.1e-42 142.4 1.6 7.3e-42 142.1 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KOS18528.1 - 0.0081 14.7 0.0 0.0085 14.6 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 KOS18528.1 - 0.081 12.9 0.4 0.18 11.8 0.3 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 RRM_1 PF00076.17 KOS18529.1 - 8e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS18529.1 - 0.00025 20.9 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS18529.1 - 0.025 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.8 KOS18530.1 - 0.00016 21.7 2.0 0.00016 21.7 1.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PBP1_TM PF14812.1 KOS18530.1 - 9.7 6.5 12.2 16 5.8 8.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mob_synth_C PF06463.8 KOS18531.1 - 3.2e-34 117.3 0.0 1.1e-33 115.6 0.0 1.8 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KOS18531.1 - 9.5e-20 71.4 0.0 1.6e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 KOS18531.1 - 0.0005 20.0 0.0 0.0016 18.4 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 KOS18531.1 - 0.00053 20.1 0.0 0.0015 18.6 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Dscam_C PF12355.3 KOS18531.1 - 0.65 10.2 2.2 1.2 9.4 1.5 1.3 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal MoaC PF01967.16 KOS18532.1 - 5.4e-52 175.0 5.0 6.6e-52 174.7 3.5 1.1 1 0 0 1 1 1 1 MoaC family FYVE PF01363.16 KOS18533.1 - 1.2e-15 57.1 6.8 2.1e-15 56.3 4.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 KOS18533.1 - 0.24 11.2 4.5 0.36 10.7 1.3 2.1 2 0 0 2 2 2 0 IBR domain zf-AN1 PF01428.11 KOS18533.1 - 1.6 8.6 12.7 0.68 9.8 5.6 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger ELO PF01151.13 KOS18534.1 - 9.8e-80 267.4 8.5 1.3e-79 267.0 5.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Peptidase_S10 PF00450.17 KOS18535.1 - 1.3e-129 432.9 0.5 1.7e-129 432.6 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 KOS18535.1 - 1.5e-05 25.0 0.0 2.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide tRNA-synt_1b PF00579.20 KOS18536.1 - 7.9e-19 67.8 0.2 3.5e-18 65.7 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) NARP1 PF12569.3 KOS18536.1 - 7.3 5.2 10.5 10 4.7 7.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 IF4E PF01652.13 KOS18537.1 - 1.5e-33 115.6 0.0 1.8e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Kinesin PF00225.18 KOS18538.1 - 3.1e-111 371.3 0.1 2.8e-110 368.1 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain AAA_33 PF13671.1 KOS18538.1 - 0.0049 16.7 2.6 0.25 11.2 0.8 3.2 3 0 0 3 3 3 1 AAA domain Microvir_lysis PF04517.7 KOS18538.1 - 0.12 12.1 0.3 0.27 10.9 0.2 1.6 1 0 0 1 1 1 0 Microvirus lysis protein (E), C terminus DUF2457 PF10446.4 KOS18538.1 - 0.75 8.4 20.0 1.4 7.5 13.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Astro_capsid PF03115.9 KOS18538.1 - 1 7.5 5.0 1.4 7.0 3.5 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor TPR_MLP1_2 PF07926.7 KOS18538.1 - 1.5 8.5 16.4 0.22 11.2 5.6 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 KOS18538.1 - 2.1 7.5 20.1 1.8 7.6 7.5 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TFIIA PF03153.8 KOS18538.1 - 5.9 6.6 15.6 11 5.7 10.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.7 KOS18538.1 - 9.5 5.3 8.3 15 4.7 5.8 1.3 1 0 0 1 1 1 0 NOA36 protein Lactamase_B PF00753.22 KOS18539.1 - 6.8e-28 97.6 2.0 1.1e-27 96.9 1.4 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KOS18539.1 - 1.4e-06 27.9 0.1 2.5e-06 27.1 0.1 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KOS18539.1 - 0.00016 21.4 0.1 0.00045 19.9 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF1236 PF06823.7 KOS18539.1 - 0.0077 15.9 0.2 0.08 12.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1236) EF-hand_6 PF13405.1 KOS18540.1 - 0.00016 21.3 0.1 0.63 10.0 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 KOS18540.1 - 0.0029 17.4 0.0 0.049 13.5 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 KOS18540.1 - 0.0055 16.8 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair HA2 PF04408.18 KOS18541.1 - 1.2e-19 70.2 0.4 4.3e-19 68.4 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KOS18541.1 - 3.7e-16 58.9 0.0 8.2e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KOS18541.1 - 3.6e-14 52.3 0.0 8.4e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS18541.1 - 5.6e-10 38.9 0.1 1.5e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.17 KOS18541.1 - 7.1e-08 32.3 0.3 1.5e-07 31.3 0.2 1.6 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.1 KOS18541.1 - 4.9e-05 23.4 0.1 0.00013 22.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain UBA PF00627.26 KOS18541.1 - 0.00013 21.6 0.2 0.0012 18.5 0.0 2.9 2 0 0 2 2 2 1 UBA/TS-N domain DND1_DSRM PF14709.1 KOS18541.1 - 0.0012 19.0 0.1 0.0033 17.6 0.1 1.8 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_25 PF13481.1 KOS18541.1 - 0.0016 17.8 0.0 0.005 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KOS18541.1 - 0.0026 17.2 0.0 0.0069 15.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 KOS18541.1 - 0.0053 15.8 0.1 0.016 14.2 0.0 1.8 2 0 0 2 2 2 1 KaiC T2SE PF00437.15 KOS18541.1 - 0.0076 15.1 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 KOS18541.1 - 0.012 15.3 0.0 0.035 13.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 KOS18541.1 - 0.098 12.9 0.0 0.098 12.9 0.0 2.1 3 0 0 3 3 2 0 AAA domain Arm PF00514.18 KOS18542.1 - 1.3e-92 300.7 15.0 4.2e-13 48.5 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KOS18542.1 - 4.5e-24 84.5 0.1 7.4e-10 38.9 0.0 6.0 1 1 5 6 6 6 6 HEAT repeats IBB PF01749.15 KOS18542.1 - 4.2e-23 81.3 0.9 7.2e-23 80.5 0.6 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KOS18542.1 - 2e-21 75.8 9.1 1.1e-09 38.4 0.1 6.1 5 1 0 5 5 5 4 HEAT-like repeat HEAT PF02985.17 KOS18542.1 - 1.2e-18 65.4 2.3 4.3e-06 26.3 0.0 7.0 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.8 KOS18542.1 - 1.9e-10 40.3 0.0 0.027 13.5 0.0 4.1 2 1 2 4 4 4 4 Armadillo-like Adaptin_N PF01602.15 KOS18542.1 - 3e-05 22.5 0.0 0.0012 17.2 0.0 2.6 1 1 2 3 3 3 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 KOS18542.1 - 0.00077 19.3 0.0 3 7.7 0.0 4.3 2 1 2 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.11 KOS18542.1 - 0.0013 18.9 0.2 1.4 9.6 0.0 4.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 KOS18542.1 - 0.0018 16.6 0.2 0.2 9.8 0.0 2.9 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit Glycos_trans_3N PF02885.12 KOS18542.1 - 0.012 15.1 0.0 18 5.0 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain AT_hook PF02178.14 KOS18543.1 - 0.16 11.7 40.1 0.62 9.9 3.8 4.9 4 0 0 4 4 4 0 AT hook motif Anophelin PF10731.4 KOS18543.1 - 2.5 8.2 7.6 0.16 12.0 1.3 1.9 1 1 1 2 2 2 0 Thrombin inhibitor from mosquito DcpS_C PF11969.3 KOS18544.1 - 5.6e-15 55.5 0.1 7.6e-07 29.3 0.1 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KOS18544.1 - 2.4e-14 53.6 0.0 1.7e-13 50.9 0.0 2.0 1 1 0 1 1 1 1 HIT domain SIMPL PF04402.9 KOS18544.1 - 0.55 10.0 2.0 6.4 6.5 2.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF541) Las1 PF04031.8 KOS18545.1 - 1e-50 171.3 0.6 1.9e-50 170.5 0.4 1.4 1 0 0 1 1 1 1 Las1-like Sec62 PF03839.11 KOS18545.1 - 0.12 11.7 0.8 0.19 11.1 0.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 CobT PF06213.7 KOS18545.1 - 0.16 11.0 6.9 0.24 10.4 4.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 KOS18545.1 - 0.36 9.2 10.1 0.55 8.6 7.0 1.2 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 KOS18545.1 - 1.6 8.2 9.8 3.2 7.2 6.4 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop14 PF04147.7 KOS18545.1 - 2 6.1 9.9 3.1 5.6 6.9 1.3 1 0 0 1 1 1 0 Nop14-like family DBINO PF13892.1 KOS18545.1 - 2.5 8.1 8.7 4.1 7.4 6.0 1.3 1 0 0 1 1 1 0 DNA-binding domain YqfQ PF14181.1 KOS18545.1 - 5.2 7.0 7.9 1.4 8.9 2.8 1.8 2 0 0 2 2 2 0 YqfQ-like protein Memo PF01875.12 KOS18546.1 - 4.3e-63 212.7 0.0 5.3e-63 212.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein KTI12 PF08433.5 KOS18547.1 - 8.8e-65 218.5 0.0 1.4e-64 217.9 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KOS18547.1 - 6.7e-05 22.7 0.2 0.00015 21.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS18547.1 - 0.00017 22.3 0.1 0.00035 21.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KOS18547.1 - 0.00054 20.2 0.0 0.0017 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain 6PF2K PF01591.13 KOS18547.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_16 PF13191.1 KOS18547.1 - 0.012 15.5 0.5 0.036 14.0 0.2 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 KOS18547.1 - 0.081 12.8 0.0 0.18 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF1792 PF08759.6 KOS18547.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) AAA_22 PF13401.1 KOS18547.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DRMBL PF07522.9 KOS18548.1 - 1.5e-33 115.0 0.0 2.7e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KOS18548.1 - 8.9e-12 44.9 0.0 2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KOS18548.1 - 0.056 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily LSM PF01423.17 KOS18551.1 - 5.9e-16 57.7 0.8 8.2e-16 57.3 0.6 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KOS18551.1 - 0.00068 19.5 0.1 0.00092 19.0 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain Glutaredoxin2_C PF04399.8 KOS18551.1 - 0.049 13.2 0.1 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain E2_bind PF08825.5 KOS18552.1 - 1.7e-30 104.5 0.1 2.8e-30 103.9 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 KOS18552.1 - 1.1e-24 85.7 0.3 2.3e-24 84.7 0.2 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KOS18552.1 - 3.6e-15 55.0 2.2 3.6e-15 55.0 1.5 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site ThiF PF00899.16 KOS18552.1 - 2.5e-14 53.2 0.1 6.5e-14 51.9 0.0 1.7 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 KOS18552.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 MoeZ/MoeB domain UAE_UbL PF14732.1 KOS18552.1 - 0.025 14.6 0.0 0.069 13.2 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_C PF09358.5 KOS18552.1 - 0.086 13.0 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain RNA_pol_A_bac PF01000.21 KOS18553.1 - 9e-25 87.0 0.0 2.1e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KOS18553.1 - 3.7e-15 54.7 0.0 4.9e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.20 KOS18554.1 - 4.3e-56 189.9 0.0 6.1e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS18554.1 - 6.1e-41 140.2 0.0 9.1e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS18554.1 - 5e-05 23.1 2.8 0.01 15.5 0.1 3.5 2 2 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KOS18554.1 - 0.0002 20.3 0.0 0.00037 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KOS18554.1 - 0.00069 18.7 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KOS18554.1 - 0.14 11.4 0.0 0.43 9.8 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Telomere_reg-2 PF10193.4 KOS18555.1 - 2.7e-10 40.5 0.0 6.1e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Telomere length regulation protein WD40 PF00400.27 KOS18556.1 - 8.6e-76 247.3 21.4 2e-08 33.8 0.1 12.6 13 0 0 13 13 13 11 WD domain, G-beta repeat Utp12 PF04003.7 KOS18556.1 - 8.3e-21 73.9 0.1 1.3e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KOS18556.1 - 6.6e-06 24.5 3.3 0.046 11.8 0.2 5.3 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KOS18556.1 - 2.8e-05 23.0 2.1 1.4 7.5 0.0 5.7 2 2 2 6 6 6 1 Nup133 N terminal like DUF3312 PF11768.3 KOS18556.1 - 0.026 12.7 0.0 0.31 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Ala_racemase_C PF00842.16 KOS18556.1 - 0.04 13.3 0.0 0.22 10.9 0.0 2.1 2 0 0 2 2 2 0 Alanine racemase, C-terminal domain eIF2A PF08662.6 KOS18556.1 - 0.062 13.0 0.1 1.8 8.2 0.0 3.4 3 1 1 4 4 3 0 Eukaryotic translation initiation factor eIF2A Lipoxygenase PF00305.14 KOS18557.1 - 4.8e-22 77.7 0.0 6.9e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase Pyridoxal_deC PF00282.14 KOS18559.1 - 1.1e-17 63.5 0.0 1.7e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KOS18559.1 - 6.2e-05 21.8 0.0 0.00012 20.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KOS18559.1 - 0.00029 20.0 0.0 0.00042 19.4 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family BCDHK_Adom3 PF10436.4 KOS18560.1 - 5.4e-70 234.1 0.0 1.6e-69 232.6 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KOS18560.1 - 1.5e-14 53.6 0.0 4.3e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KOS18560.1 - 0.0027 17.3 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Macoilin PF09726.4 KOS18561.1 - 0.0013 17.1 7.2 0.0017 16.7 5.0 1.1 1 0 0 1 1 1 1 Transmembrane protein Tropomyosin_1 PF12718.2 KOS18561.1 - 0.1 12.4 6.4 0.31 10.8 4.4 1.8 1 0 0 1 1 1 0 Tropomyosin like GP41 PF00517.12 KOS18561.1 - 0.24 10.9 4.4 0.44 10.0 3.0 1.5 1 0 0 1 1 1 0 Retroviral envelope protein Seryl_tRNA_N PF02403.17 KOS18561.1 - 0.74 9.8 7.2 0.49 10.4 2.9 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 KOS18561.1 - 2.6 7.5 14.1 6.2 6.3 6.5 2.5 2 0 0 2 2 2 0 IncA protein FadA PF09403.5 KOS18561.1 - 3.2 7.7 9.5 0.47 10.4 3.0 2.2 3 0 0 3 3 3 0 Adhesion protein FadA Atg14 PF10186.4 KOS18561.1 - 4.1 6.2 11.8 2.6 6.8 5.9 2.1 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 KOS18561.1 - 4.7 7.3 6.1 12 6.0 4.3 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family LRS4 PF10422.4 KOS18561.1 - 5.1 6.3 10.5 0.1 11.9 2.1 1.9 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 HR1 PF02185.11 KOS18561.1 - 7.8 6.3 10.0 2.7 7.7 3.5 2.7 2 1 0 2 2 2 0 Hr1 repeat DUF1771 PF08590.5 KOS18562.1 - 9.1e-22 76.8 12.3 1.5e-21 76.2 8.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KOS18562.1 - 2.8e-14 53.0 0.3 5.7e-14 52.0 0.2 1.5 1 0 0 1 1 1 1 Smr domain RHD PF00554.17 KOS18562.1 - 0.008 15.9 0.5 0.014 15.1 0.4 1.3 1 0 0 1 1 1 1 Rel homology domain (RHD) DUF4407 PF14362.1 KOS18562.1 - 0.072 12.0 1.5 0.085 11.8 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_Mu_F PF04233.9 KOS18562.1 - 0.093 13.2 2.0 0.25 11.8 1.4 2.0 1 1 0 1 1 1 0 Phage Mu protein F like protein Stc1 PF12898.2 KOS18563.1 - 6.4e-14 51.7 1.4 1.4e-13 50.7 0.9 1.6 1 0 0 1 1 1 1 Stc1 domain zf-CHY PF05495.7 KOS18563.1 - 0.074 13.2 0.9 0.17 12.0 0.6 1.6 1 0 0 1 1 1 0 CHY zinc finger Fungal_trans_2 PF11951.3 KOS18565.1 - 1.8e-08 33.3 0.2 1.7e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Glyco_hydro_16 PF00722.16 KOS18566.1 - 8.7e-14 51.2 0.1 1.3e-13 50.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TraG-D_C PF12696.2 KOS18566.1 - 0.036 13.9 0.0 0.18 11.6 0.0 2.1 2 1 1 3 3 3 0 TraM recognition site of TraD and TraG Lung_7-TM_R PF06814.8 KOS18567.1 - 1.6e-40 138.9 16.2 3.7e-40 137.7 8.6 2.0 1 1 1 2 2 2 2 Lung seven transmembrane receptor DUF1673 PF07895.6 KOS18567.1 - 1.2 8.6 6.6 2.2 7.7 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF4131 PF13567.1 KOS18567.1 - 6.5 6.1 11.8 0.12 11.8 1.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) PrgI PF12666.2 KOS18567.1 - 9.6 6.4 13.4 0.61 10.2 2.3 2.6 1 1 2 3 3 3 0 PrgI family protein Pro_isomerase PF00160.16 KOS18568.1 - 9.8e-48 162.2 0.1 1.7e-47 161.5 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 KOS18568.1 - 0.00037 20.3 0.1 0.0035 17.2 0.0 2.6 2 0 0 2 2 2 1 U-box domain RasGEF PF00617.14 KOS18569.1 - 4.4e-62 209.1 0.5 7.4e-62 208.4 0.3 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KOS18569.1 - 2.3e-27 95.0 1.1 4.6e-27 94.1 0.7 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KOS18569.1 - 5.7e-16 57.6 0.1 1.4e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KOS18569.1 - 1.8e-14 53.0 0.9 4.5e-14 51.7 0.2 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KOS18569.1 - 1.8e-13 49.7 0.1 4.7e-13 48.4 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 KOS18569.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 WW domain NOA36 PF06524.7 KOS18569.1 - 5.8 6.0 7.2 9.8 5.3 5.0 1.3 1 0 0 1 1 1 0 NOA36 protein Herpes_UL32 PF06070.6 KOS18570.1 - 0.17 10.3 5.5 0.18 10.2 3.8 1.3 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Fungal_trans PF04082.13 KOS18571.1 - 0.022 13.6 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Atrophin-1 PF03154.10 KOS18572.1 - 0.014 13.5 15.9 0.016 13.4 11.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family Trypan_PARP PF05887.6 KOS18572.1 - 0.043 13.6 8.1 0.045 13.5 5.6 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Vfa1 PF08432.5 KOS18572.1 - 0.11 12.5 14.7 0.11 12.5 10.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SR-25 PF10500.4 KOS18572.1 - 0.13 11.7 12.8 0.12 11.7 8.9 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1510 PF07423.6 KOS18572.1 - 0.15 11.4 12.2 0.14 11.5 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2956 PF11169.3 KOS18572.1 - 0.19 11.6 9.8 0.2 11.6 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) MIP-T3 PF10243.4 KOS18572.1 - 0.21 10.0 18.7 0.22 9.9 13.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HNOBA PF07701.9 KOS18572.1 - 0.37 9.9 5.0 0.37 9.9 3.5 1.0 1 0 0 1 1 1 0 Heme NO binding associated Sec62 PF03839.11 KOS18572.1 - 0.41 10.0 9.5 0.4 10.0 6.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 BLVR PF06375.6 KOS18572.1 - 0.45 10.3 13.3 0.44 10.3 9.2 1.0 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Peptidase_U57 PF05582.7 KOS18572.1 - 0.49 9.3 3.7 0.5 9.2 2.6 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Paf1 PF03985.8 KOS18572.1 - 0.62 8.7 12.1 0.59 8.8 8.4 1.0 1 0 0 1 1 1 0 Paf1 BNIP3 PF06553.7 KOS18572.1 - 0.71 9.2 7.0 0.88 8.9 4.9 1.3 1 0 0 1 1 1 0 BNIP3 Rtf2 PF04641.7 KOS18572.1 - 0.77 8.9 10.1 0.7 9.0 7.0 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Adeno_PV PF03910.8 KOS18572.1 - 1 8.3 11.3 1.1 8.2 7.9 1.0 1 0 0 1 1 1 0 Adenovirus minor core protein PV Pox_Ag35 PF03286.9 KOS18572.1 - 1.2 8.6 13.1 1.3 8.5 9.1 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein YqfQ PF14181.1 KOS18572.1 - 1.3 9.0 12.8 1.5 8.8 8.9 1.0 1 0 0 1 1 1 0 YqfQ-like protein Hom_end_hint PF05203.11 KOS18572.1 - 1.3 8.6 5.1 1.3 8.7 3.5 1.0 1 0 0 1 1 1 0 Hom_end-associated Hint UBN_AB PF14075.1 KOS18572.1 - 1.4 8.5 11.0 1.4 8.5 7.7 1.0 1 0 0 1 1 1 0 Ubinuclein conserved middle domain FAM176 PF14851.1 KOS18572.1 - 1.5 8.5 7.5 1.5 8.4 5.2 1.1 1 0 0 1 1 1 0 FAM176 family HSP90 PF00183.13 KOS18572.1 - 1.5 7.1 13.8 1.5 7.1 9.6 1.0 1 0 0 1 1 1 0 Hsp90 protein Spore_coat_CotO PF14153.1 KOS18572.1 - 1.7 8.0 13.2 1.7 8.0 9.2 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Tom22 PF04281.8 KOS18572.1 - 1.8 8.1 8.6 2.2 7.8 6.0 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF3451 PF11933.3 KOS18572.1 - 2.1 8.0 10.3 2 8.1 7.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) NARP1 PF12569.3 KOS18572.1 - 2.3 6.9 12.8 2 7.0 8.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GAGA_bind PF06217.7 KOS18572.1 - 2.3 8.1 7.2 2.1 8.2 5.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family TRAP_alpha PF03896.11 KOS18572.1 - 2.5 7.0 6.5 2.3 7.1 4.5 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.5 KOS18572.1 - 2.7 8.2 6.2 3.2 8.0 4.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DDRGK PF09756.4 KOS18572.1 - 2.7 7.3 20.6 3 7.2 14.3 1.0 1 0 0 1 1 1 0 DDRGK domain DUF3824 PF12868.2 KOS18572.1 - 3 8.7 8.0 4.3 8.2 5.6 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) RNA_pol_Rpc4 PF05132.9 KOS18572.1 - 3.1 7.8 10.3 3.2 7.7 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Tim54 PF11711.3 KOS18572.1 - 3.1 6.3 9.8 2.9 6.3 6.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FPN1 PF06963.7 KOS18572.1 - 3.1 6.0 4.4 2.9 6.1 3.0 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) CDC45 PF02724.9 KOS18572.1 - 3.4 5.6 11.5 3.4 5.5 8.0 1.0 1 0 0 1 1 1 0 CDC45-like protein XRN_N PF03159.13 KOS18572.1 - 3.6 6.8 5.8 3.6 6.9 4.0 1.0 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Peptidase_S49_N PF08496.5 KOS18572.1 - 3.8 7.2 13.0 4.1 7.1 9.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ycf1 PF05758.7 KOS18572.1 - 4.1 4.9 10.9 3.8 5.0 7.6 1.0 1 0 0 1 1 1 0 Ycf1 RNA_polI_A34 PF08208.6 KOS18572.1 - 4.1 7.0 21.0 4.5 6.8 14.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.12 KOS18572.1 - 4.1 7.1 8.1 3.9 7.1 5.6 1.0 1 0 0 1 1 1 0 DDHD domain Radial_spoke PF04712.7 KOS18572.1 - 4.1 6.0 13.5 4.3 5.9 9.3 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Poxvirus_B22R PF04395.7 KOS18572.1 - 4.9 6.5 7.9 5.2 6.5 5.5 1.0 1 0 0 1 1 1 0 Poxvirus B22R protein Prog_receptor PF02161.10 KOS18572.1 - 5.2 5.7 6.9 5.5 5.7 4.8 1.0 1 0 0 1 1 1 0 Progesterone receptor DUF3987 PF13148.1 KOS18572.1 - 5.7 5.3 12.7 5.5 5.4 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) OAD_gamma PF04277.8 KOS18572.1 - 5.9 7.3 8.9 7.4 7.0 6.2 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Folate_carrier PF01770.13 KOS18572.1 - 6 5.2 5.3 5.7 5.3 3.7 1.0 1 0 0 1 1 1 0 Reduced folate carrier EIIBC-GUT_N PF03612.9 KOS18572.1 - 6.5 6.3 6.0 6.6 6.3 4.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus VID27 PF08553.5 KOS18572.1 - 7.1 4.7 10.5 6.9 4.7 7.3 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein RR_TM4-6 PF06459.7 KOS18572.1 - 7.7 6.3 14.5 7.8 6.3 10.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rota_VP2 PF05087.7 KOS18572.1 - 8.4 4.1 9.3 7.8 4.2 6.5 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein PEX11 PF05648.9 KOS18572.1 - 9.6 5.3 6.6 11 5.2 4.6 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) ATP-synt_E PF05680.7 KOS18572.1 - 9.7 6.2 13.1 10 6.1 9.1 1.1 1 0 0 1 1 1 0 ATP synthase E chain AIF_C PF14721.1 KOS18572.1 - 10 6.4 7.1 12 6.1 4.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term zf-C2HC_2 PF13913.1 KOS18573.1 - 0.013 15.0 0.6 0.021 14.4 0.4 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type LsmAD PF06741.8 KOS18573.1 - 0.63 10.1 12.0 1.7 8.8 8.3 1.7 1 0 0 1 1 1 0 LsmAD domain Mito_carr PF00153.22 KOS18574.1 - 2.3e-41 139.4 0.0 8.1e-14 51.1 0.0 3.9 3 2 0 3 3 3 3 Mitochondrial carrier protein ATG_C PF09333.6 KOS18574.1 - 0.14 12.3 0.0 0.59 10.3 0.0 2.0 2 0 0 2 2 2 0 ATG C terminal domain WW PF00397.21 KOS18575.1 - 1.5e-06 27.8 3.8 3.6e-06 26.7 2.6 1.6 1 0 0 1 1 1 1 WW domain RIX1 PF08167.7 KOS18576.1 - 3.8e-43 147.0 0.6 7.6e-43 146.0 0.4 1.5 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis TPR_8 PF13181.1 KOS18577.1 - 3.2e-06 26.5 2.2 0.0034 17.0 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS18577.1 - 1.8e-05 24.9 3.3 0.13 12.6 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KOS18577.1 - 0.0019 18.6 28.7 0.19 12.4 0.1 8.9 10 1 1 11 11 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 KOS18577.1 - 0.0033 17.5 3.6 0.1 12.8 0.1 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KOS18577.1 - 0.0063 16.3 21.8 0.097 12.6 0.0 7.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.1 KOS18577.1 - 0.013 15.1 7.1 9.8 5.9 0.0 4.8 6 0 0 6 6 6 0 TPR repeat TPR_12 PF13424.1 KOS18577.1 - 0.056 13.3 11.0 9 6.3 0.2 6.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 KOS18577.1 - 0.099 12.2 12.3 5.3 6.8 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 KOS18577.1 - 0.12 13.0 23.3 5.5 7.7 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 KOS18577.1 - 0.49 10.9 10.3 2.9 8.5 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KOS18577.1 - 5.2 7.1 14.4 7.1 6.6 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat RTA1 PF04479.8 KOS18578.1 - 1.6e-39 135.7 4.2 4.8e-28 98.1 3.4 2.1 2 0 0 2 2 2 2 RTA1 like protein Cwf_Cwc_15 PF04889.7 KOS18579.1 - 0.086 12.5 13.0 0.14 11.8 9.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.6 KOS18579.1 - 1.2 8.6 9.6 1.8 8.0 6.7 1.3 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.7 KOS18579.1 - 1.8 7.7 10.4 2.6 7.2 7.2 1.2 1 0 0 1 1 1 0 NOA36 protein bZIP_1 PF00170.16 KOS18581.1 - 3.9e-06 26.7 9.6 5.5e-06 26.2 6.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor GvpL_GvpF PF06386.6 KOS18581.1 - 0.0066 16.0 2.7 0.0078 15.8 1.8 1.1 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpL/GvpF Effector_1 PF04518.7 KOS18581.1 - 0.0092 15.0 1.2 0.01 14.8 0.8 1.0 1 0 0 1 1 1 1 Effector from type III secretion system Tom37_C PF11801.3 KOS18581.1 - 0.047 13.5 0.5 0.054 13.3 0.4 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain Glutaredoxin2_C PF04399.8 KOS18581.1 - 0.083 12.4 0.5 0.11 12.1 0.3 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain CAF-1_p150 PF11600.3 KOS18581.1 - 0.12 11.7 6.5 0.14 11.5 4.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Fib_alpha PF08702.5 KOS18581.1 - 0.13 12.3 1.1 0.16 12.0 0.7 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.1 KOS18581.1 - 0.26 10.2 3.3 0.28 10.1 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ndc1_Nup PF09531.5 KOS18581.1 - 0.31 9.4 3.5 0.34 9.2 2.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup bZIP_2 PF07716.10 KOS18581.1 - 0.47 10.3 11.5 0.37 10.6 6.6 1.8 1 1 1 2 2 2 0 Basic region leucine zipper DUF2852 PF11014.3 KOS18581.1 - 2 8.3 4.6 3.8 7.4 3.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Glyco_hydro_16 PF00722.16 KOS18582.1 - 1.3e-06 27.7 0.1 2.1e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Xpo1 PF08389.7 KOS18584.1 - 1.2e-34 119.3 0.4 1.6e-33 115.7 0.0 3.1 4 0 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 KOS18584.1 - 0.0027 17.6 0.1 3 8.1 0.0 4.3 5 0 0 5 5 5 1 HEAT repeat DUF3407 PF11887.3 KOS18584.1 - 0.012 14.9 0.2 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) Prefoldin_2 PF01920.15 KOS18584.1 - 1.1 9.0 6.7 2.6 7.8 0.0 2.9 3 0 0 3 3 3 0 Prefoldin subunit Gtr1_RagA PF04670.7 KOS18585.1 - 1.9e-51 174.4 0.3 2.4e-51 174.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region OGG_N PF07934.7 KOS18585.1 - 0.04 13.8 0.0 0.065 13.1 0.0 1.5 1 1 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain VHS PF00790.14 KOS18586.1 - 2.6e-05 23.9 0.0 0.00046 19.8 0.0 2.4 2 0 0 2 2 2 1 VHS domain CTD_bind PF04818.8 KOS18586.1 - 0.00088 19.4 0.0 0.002 18.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Suf PF05843.9 KOS18586.1 - 0.12 12.0 5.3 0.3 10.7 3.7 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Aconitase PF00330.15 KOS18587.1 - 7.1e-72 242.3 0.0 4.8e-45 153.9 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KOS18587.1 - 3.3e-21 75.7 0.0 5.9e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Apc4 PF12896.2 KOS18588.1 - 4.6e-51 173.1 0.0 6.8e-51 172.5 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 WD40 PF00400.27 KOS18588.1 - 0.022 14.6 0.4 0.54 10.2 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat CPSF_A PF03178.10 KOS18588.1 - 0.04 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 CPSF A subunit region DUF2264 PF10022.4 KOS18589.1 - 1.8e-116 388.7 0.2 2.2e-116 388.4 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Glyco_hydro_88 PF07470.8 KOS18590.1 - 3e-12 46.2 0.8 4.2e-12 45.7 0.5 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.13 KOS18591.1 - 2.2e-11 43.1 0.0 3.7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS18591.1 - 7.1e-09 35.4 11.5 1.4e-08 34.5 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOXp PF12336.3 KOS18591.1 - 0.029 14.9 0.1 0.066 13.8 0.1 1.5 1 0 0 1 1 1 0 SOX transcription factor Dickkopf_N PF04706.7 KOS18591.1 - 0.32 11.2 6.8 0.81 9.9 4.7 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Sugar_tr PF00083.19 KOS18592.1 - 1.9e-73 247.5 21.5 2.3e-73 247.3 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS18592.1 - 4e-31 108.0 44.6 4.4e-26 91.4 18.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Transp_cyt_pur PF02133.10 KOS18593.1 - 2.6e-21 75.7 34.6 7.7e-21 74.1 24.0 1.7 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Alginate_lyase PF05426.7 KOS18594.1 - 2.7e-79 266.3 0.0 3.8e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 Alginate lyase Alpha-amylase_C PF02806.13 KOS18595.1 - 1.4e-26 92.4 0.0 2.6e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain AAA_2 PF07724.9 KOS18596.1 - 2.5e-33 115.3 0.0 4.8e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KOS18596.1 - 1.3e-12 48.0 0.0 2.1e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KOS18596.1 - 2.5e-09 36.9 0.0 5.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KOS18596.1 - 1.3e-05 24.9 0.0 2.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KOS18596.1 - 2.5e-05 24.4 0.1 7.5e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS18596.1 - 5.8e-05 23.1 0.2 0.0035 17.3 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain MCM PF00493.18 KOS18596.1 - 9.2e-05 21.3 0.0 0.00014 20.7 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family AAA_17 PF13207.1 KOS18596.1 - 0.00013 22.7 0.0 0.0003 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KOS18596.1 - 0.00053 19.8 0.0 0.00089 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KOS18596.1 - 0.0049 16.3 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KOS18596.1 - 0.011 14.9 0.0 0.31 10.1 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 KOS18596.1 - 0.016 14.6 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DEAD PF00270.24 KOS18596.1 - 0.024 14.1 0.0 1.4 8.4 0.0 2.5 3 0 0 3 3 3 0 DEAD/DEAH box helicase ABC_tran PF00005.22 KOS18596.1 - 0.027 14.7 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 KOS18596.1 - 0.031 13.7 0.0 0.21 11.0 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain T2SE PF00437.15 KOS18596.1 - 0.035 13.0 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 KOS18596.1 - 0.064 12.9 0.0 0.79 9.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ResIII PF04851.10 KOS18596.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 KOS18596.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain STN PF07660.9 KOS18596.1 - 0.12 11.9 0.1 6.8 6.3 0.1 2.5 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain Alpha-amylase PF00128.19 KOS18597.1 - 1e-18 67.8 0.8 1.8e-14 53.8 0.3 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 KOS18597.1 - 1.2e-15 57.3 0.0 2.8e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Fungal_trans PF04082.13 KOS18598.1 - 5.1e-11 41.9 0.5 8.6e-11 41.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MOFRL PF05161.8 KOS18598.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 MOFRL family COX4 PF02936.9 KOS18599.1 - 3.7e-48 162.8 0.1 4.4e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.6 KOS18599.1 - 0.15 12.1 0.2 0.78 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) TPT PF03151.11 KOS18600.1 - 4.5e-42 143.2 0.9 4.5e-42 143.2 0.6 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KOS18600.1 - 3e-10 39.5 11.4 4.1e-09 35.7 7.9 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KOS18600.1 - 2e-08 34.2 26.9 0.00021 21.3 7.7 3.2 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KOS18600.1 - 0.012 14.6 0.4 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Nucleotide-sugar transporter ORC5_C PF14630.1 KOS18601.1 - 1.9e-65 221.0 0.0 6.2e-65 219.3 0.0 1.8 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus Mus7 PF09462.5 KOS18601.1 - 6.3e-08 31.9 0.1 8.1e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family AAA_22 PF13401.1 KOS18601.1 - 0.0032 17.6 0.0 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF3066 PF11266.3 KOS18601.1 - 0.01 15.5 0.0 0.094 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3066) AAA_16 PF13191.1 KOS18601.1 - 0.025 14.5 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 KOS18602.1 - 1.4e-38 132.1 0.0 2.6e-38 131.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS18602.1 - 1.7e-07 31.4 0.8 0.0067 16.5 0.0 3.4 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 KOS18602.1 - 3.2e-07 30.5 0.1 0.0054 16.7 0.0 3.6 2 1 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.7 KOS18602.1 - 6.3e-06 25.4 0.0 1.8e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KOS18602.1 - 0.00018 21.3 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS18602.1 - 0.0002 22.1 0.1 0.0017 19.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KOS18602.1 - 0.0023 17.6 0.1 0.007 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KOS18602.1 - 0.0033 17.3 0.0 0.01 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS18602.1 - 0.0052 16.5 0.1 0.016 14.9 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KOS18602.1 - 0.0055 16.1 0.4 0.21 10.9 0.2 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KOS18602.1 - 0.0076 15.4 0.1 0.017 14.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KOS18602.1 - 0.009 15.4 0.1 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KOS18602.1 - 0.013 14.2 0.1 0.029 13.0 0.0 1.5 1 1 1 2 2 2 0 TIP49 C-terminus AAA_10 PF12846.2 KOS18602.1 - 0.016 14.6 0.5 9.1 5.6 0.0 3.4 3 0 0 3 3 3 0 AAA-like domain Arch_ATPase PF01637.13 KOS18602.1 - 0.022 14.4 0.3 4.3 6.9 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase AAA_18 PF13238.1 KOS18602.1 - 0.03 14.6 0.0 0.072 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KOS18602.1 - 0.033 14.3 0.2 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 KOS18602.1 - 0.047 12.7 0.1 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 KOS18602.1 - 0.051 13.1 0.4 0.12 11.9 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KOS18602.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KOS18602.1 - 0.088 12.4 0.2 0.34 10.5 0.1 2.0 2 0 0 2 2 2 0 NACHT domain DASH_Dad2 PF08654.5 KOS18602.1 - 0.19 11.7 0.6 5.5 7.0 0.1 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad2 TFIIH_BTF_p62_N PF08567.6 KOS18603.1 - 8.8e-24 82.9 0.0 2.7e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 KOS18603.1 - 2.2e-20 72.1 4.2 6.7e-11 41.7 0.0 3.0 3 0 0 3 3 3 2 BSD domain DUF2428 PF10350.4 KOS18604.1 - 1.7e-62 210.7 0.0 2.6e-62 210.1 0.0 1.3 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 KOS18604.1 - 0.0002 21.1 16.6 0.14 12.2 0.0 7.7 7 0 0 7 7 7 2 HEAT repeat Peptidase_C27 PF05407.7 KOS18604.1 - 0.00065 19.4 0.1 0.0033 17.1 0.0 2.2 3 0 0 3 3 3 1 Rubella virus endopeptidase Ribosomal_L1 PF00687.16 KOS18605.1 - 1.4e-52 178.2 0.3 1.7e-52 177.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family EST1_DNA_bind PF10373.4 KOS18606.1 - 2.7e-46 158.0 0.3 5.1e-46 157.1 0.2 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KOS18606.1 - 1.5e-19 70.3 0.1 3.7e-19 69.0 0.1 1.7 1 0 0 1 1 1 1 Telomerase activating protein Est1 DUF3074 PF11274.3 KOS18607.1 - 1.2e-53 181.4 2.0 1.3e-51 174.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) CAF-1_p150 PF11600.3 KOS18607.1 - 0.012 15.0 35.5 0.023 14.0 24.6 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_13 PF13166.1 KOS18607.1 - 2 6.7 13.4 3 6.1 9.3 1.1 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 KOS18608.1 - 4.9e-74 247.3 0.1 6e-74 247.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KOS18608.1 - 3.9e-13 49.0 0.0 4.6e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KOS18608.1 - 4.8e-12 45.5 0.0 5.7e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KOS18608.1 - 5.4e-12 45.0 0.9 3.4e-08 32.5 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KOS18608.1 - 7.8e-09 36.0 0.0 1.1e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KOS18608.1 - 8.2e-09 34.9 0.0 9.4e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KOS18608.1 - 2e-06 27.7 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KOS18608.1 - 6.3e-06 25.7 0.0 0.00094 18.6 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 KOS18608.1 - 0.0075 15.0 0.3 0.026 13.2 0.1 1.9 2 1 0 2 2 2 1 ArgK protein FeoB_N PF02421.13 KOS18608.1 - 0.022 14.0 0.8 0.074 12.3 0.6 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF3986 PF13143.1 KOS18608.1 - 0.078 13.4 0.2 0.24 11.8 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) NERD PF08378.6 KOS18609.1 - 0.013 15.8 0.8 0.021 15.0 0.1 1.7 2 0 0 2 2 2 0 Nuclease-related domain Skp1 PF01466.14 KOS18611.1 - 5.4e-38 128.8 1.7 5.4e-38 128.8 1.2 1.5 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KOS18611.1 - 1.2e-18 66.9 0.0 2.7e-18 65.7 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain GMC_oxred_N PF00732.14 KOS18612.1 - 4.9e-41 140.8 0.1 6.9e-41 140.3 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KOS18612.1 - 1.8e-24 86.6 0.0 3.9e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KOS18612.1 - 8.4e-12 44.6 0.7 6e-06 25.3 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KOS18612.1 - 2.7e-09 36.3 0.5 5.2e-09 35.4 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KOS18612.1 - 9.1e-08 32.2 0.5 6e-07 29.5 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS18612.1 - 1.3e-05 25.1 1.3 2.4e-05 24.2 0.1 2.1 3 0 0 3 3 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KOS18612.1 - 2.4e-05 23.5 0.1 3.8e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KOS18612.1 - 6.1e-05 22.2 0.1 0.00014 21.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KOS18612.1 - 6.4e-05 21.5 0.1 0.00013 20.6 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KOS18612.1 - 0.00011 21.4 0.1 0.00023 20.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KOS18612.1 - 0.0041 16.0 0.4 0.042 12.6 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KOS18612.1 - 0.021 13.7 0.1 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 KOS18612.1 - 0.029 14.7 0.0 0.079 13.3 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Flocculin PF00624.13 KOS18612.1 - 0.14 12.0 0.2 0.26 11.1 0.2 1.3 1 0 0 1 1 1 0 Flocculin repeat 3HCDH_N PF02737.13 KOS18612.1 - 0.22 11.1 0.1 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDEase_I PF00233.14 KOS18613.1 - 5.6e-14 52.4 0.9 1.3e-10 41.4 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase GMC_oxred_N PF00732.14 KOS18614.1 - 2.4e-55 187.8 0.0 3.1e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KOS18614.1 - 3e-31 108.6 0.2 5.9e-31 107.6 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KOS18614.1 - 0.0097 14.8 1.1 0.018 14.0 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KOS18614.1 - 0.017 13.9 0.4 2.1 7.1 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 KOS18614.1 - 0.063 13.3 2.5 0.64 10.0 0.2 3.2 3 1 1 4 4 4 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KOS18614.1 - 0.16 10.5 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MFS_1 PF07690.11 KOS18615.1 - 6.3e-24 84.3 53.6 8e-22 77.4 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KOS18615.1 - 0.0078 16.2 0.3 0.0078 16.2 0.2 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) MFS_1 PF07690.11 KOS18617.1 - 5.5e-30 104.2 33.9 5.5e-30 104.2 23.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L4 PF00573.17 KOS18618.1 - 1.2e-40 138.9 0.3 1.8e-40 138.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KOS18618.1 - 1e-25 89.4 1.6 1e-25 89.4 1.1 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain PGA2 PF07543.7 KOS18619.1 - 2.2e-32 111.7 2.8 2.7e-32 111.4 1.9 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 COX16 PF14138.1 KOS18619.1 - 6.1 7.0 6.4 69 3.7 4.4 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DUF4428 PF14471.1 KOS18620.1 - 0.0048 16.6 0.1 0.72 9.6 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4428) zf-RING_4 PF14570.1 KOS18620.1 - 0.091 12.3 2.4 13 5.4 0.1 3.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Malic_M PF03949.10 KOS18621.1 - 8.8e-83 277.7 0.0 4.6e-82 275.4 0.0 1.9 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KOS18621.1 - 3e-70 235.4 0.0 4.4e-70 234.9 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Fungal_trans PF04082.13 KOS18622.1 - 2.7e-34 118.2 0.2 5.6e-34 117.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain GAS2 PF02187.12 KOS18623.1 - 0.0001 22.0 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Aa_trans PF01490.13 KOS18624.1 - 3.2e-67 226.7 20.0 4.1e-67 226.4 13.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein F-box PF00646.28 KOS18625.1 - 0.0011 18.5 0.1 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain Copper-fist PF00649.13 KOS18625.1 - 0.021 14.0 0.7 0.18 11.0 0.2 2.5 2 0 0 2 2 2 0 Copper fist DNA binding domain F-box-like PF12937.2 KOS18625.1 - 0.037 13.7 0.2 0.037 13.7 0.1 2.1 2 0 0 2 2 2 0 F-box-like Ras PF00071.17 KOS18627.1 - 1.3e-54 183.9 0.0 1.5e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS18627.1 - 7.3e-15 55.5 0.0 1.1e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS18627.1 - 1.7e-07 30.6 0.0 3.2e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family NB-ARC PF00931.17 KOS18627.1 - 0.001 18.0 0.0 0.0083 15.0 0.0 1.9 1 1 1 2 2 2 1 NB-ARC domain Gtr1_RagA PF04670.7 KOS18627.1 - 0.0011 18.1 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KOS18627.1 - 0.0011 18.4 0.0 0.0051 16.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KOS18627.1 - 0.0036 16.5 0.0 0.0047 16.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KOS18627.1 - 0.16 11.4 0.0 12 5.3 0.0 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RRM_1 PF00076.17 KOS18628.1 - 1.3e-13 50.3 0.0 3.3e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS18628.1 - 9.7e-09 35.0 0.0 2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS18628.1 - 4.7e-08 32.7 0.1 1.9e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cobW PF02492.14 KOS18629.1 - 2.2e-34 118.4 0.0 3.7e-34 117.6 0.0 1.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KOS18629.1 - 8.6e-06 24.7 0.8 0.00014 20.7 0.6 2.0 1 1 0 1 1 1 1 ArgK protein AAA_23 PF13476.1 KOS18629.1 - 0.013 15.8 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KOS18629.1 - 0.021 14.6 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 KOS18629.1 - 0.035 13.4 0.3 0.068 12.5 0.2 1.4 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KOS18629.1 - 0.05 13.5 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.12 KOS18629.1 - 0.088 12.2 0.1 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 KOS18629.1 - 0.13 13.1 0.3 0.3 11.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 KOS18629.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain GRAB PF10375.4 KOS18631.1 - 6.6e-09 35.0 0.1 1.4e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Myosin_tail_1 PF01576.14 KOS18631.1 - 0.00019 19.3 53.3 0.00029 18.7 36.9 1.2 1 0 0 1 1 1 1 Myosin tail Rootletin PF15035.1 KOS18631.1 - 0.0033 17.4 17.9 0.0033 17.4 12.4 3.8 2 1 2 4 4 3 2 Ciliary rootlet component, centrosome cohesion NPV_P10 PF05531.7 KOS18631.1 - 0.015 15.5 14.2 0.12 12.6 0.7 4.2 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 KOS18631.1 - 0.016 14.4 13.5 0.018 14.2 0.9 3.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 KOS18631.1 - 0.021 14.7 5.4 0.021 14.7 3.7 5.5 5 1 1 6 6 6 0 bZIP transcription factor F_actin_bind PF08919.5 KOS18631.1 - 0.12 12.0 7.4 1.5 8.5 0.7 3.3 2 2 0 2 2 2 0 F-actin binding Prominin PF05478.6 KOS18631.1 - 0.25 8.8 22.5 0.39 8.1 4.1 2.1 1 1 1 2 2 2 0 Prominin Baculo_PEP_C PF04513.7 KOS18631.1 - 0.63 9.8 13.5 2.2 8.1 1.2 3.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.4 KOS18631.1 - 0.77 8.6 42.6 0.018 13.9 12.8 3.2 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Filament PF00038.16 KOS18631.1 - 0.97 8.8 50.0 0.65 9.4 17.5 3.0 1 1 2 3 3 3 0 Intermediate filament protein GAS PF13851.1 KOS18631.1 - 4.2 6.5 47.8 0.057 12.6 8.4 4.1 2 2 2 4 4 4 0 Growth-arrest specific micro-tubule binding Spectrin PF00435.16 KOS18631.1 - 4.2 7.7 40.9 2.6 8.3 7.0 4.8 2 1 3 5 5 5 0 Spectrin repeat DUF1664 PF07889.7 KOS18631.1 - 4.6 7.0 22.4 0.36 10.6 2.6 3.9 2 2 1 4 4 4 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 KOS18631.1 - 5.8 6.8 21.3 17 5.4 0.2 6.0 3 2 1 5 5 5 0 Flagella accessory protein C (FlaC) Fun_ATP-synt_8 PF05933.8 KOS18632.1 - 0.55 10.3 2.7 1.3 9.0 1.9 1.6 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) 4F5 PF04419.9 KOS18633.1 - 1.6e-06 28.7 13.4 1.6e-06 28.7 9.3 2.3 1 1 1 2 2 2 1 4F5 protein family DUF1778 PF08681.6 KOS18633.1 - 0.00055 19.7 3.2 0.0007 19.3 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1778) ELO PF01151.13 KOS18634.1 - 1.5e-62 211.1 20.9 1.8e-62 210.8 14.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family F-box-like PF12937.2 KOS18635.1 - 6.8e-06 25.7 0.1 1.4e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS18635.1 - 0.015 14.9 0.3 0.84 9.3 0.2 2.6 2 0 0 2 2 2 0 F-box domain DUF3317 PF11779.3 KOS18636.1 - 2.1e-16 59.1 1.3 3e-16 58.5 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) RF-1 PF00472.15 KOS18637.1 - 3.2e-25 88.1 2.4 5.1e-25 87.4 1.6 1.3 1 0 0 1 1 1 1 RF-1 domain MIR PF02815.14 KOS18637.1 - 0.09 12.2 0.1 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 MIR domain Urm1 PF09138.6 KOS18638.1 - 1.1e-25 89.5 0.0 1.2e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KOS18638.1 - 0.0011 19.3 0.0 0.0013 19.1 0.0 1.1 1 0 0 1 1 1 1 ThiS family WD40 PF00400.27 KOS18639.1 - 2e-55 182.8 21.4 3.6e-07 29.8 0.1 11.6 12 0 0 12 12 12 9 WD domain, G-beta repeat Mito_carr PF00153.22 KOS18640.1 - 2.8e-57 190.4 2.4 2.4e-18 65.6 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_fiss_reg PF05308.6 KOS18640.1 - 0.0043 16.4 2.8 0.0074 15.6 2.0 1.4 1 0 0 1 1 1 1 Mitochondrial fission regulator NeA_P2 PF12312.3 KOS18640.1 - 0.087 12.0 0.8 0.14 11.3 0.6 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein DUF2613 PF11021.3 KOS18640.1 - 0.26 11.0 3.2 0.97 9.1 2.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2613) zf-H2C2_2 PF13465.1 KOS18641.1 - 2e-19 68.8 17.8 3.9e-08 33.1 0.2 4.7 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 KOS18641.1 - 4.9e-19 67.4 18.4 3.3e-05 23.9 0.5 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS18641.1 - 4.9e-15 54.6 15.1 0.00071 19.7 0.2 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger TipAS PF07739.8 KOS18641.1 - 0.074 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain zf-C2H2_6 PF13912.1 KOS18641.1 - 1.1 9.2 7.3 5.6 7.0 0.0 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger Zip PF02535.17 KOS18641.1 - 1.4 7.8 8.4 2.6 6.9 5.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter zf-LYAR PF08790.6 KOS18641.1 - 4.4 7.1 5.6 18 5.1 0.2 3.8 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Cohesin_load PF10345.4 KOS18642.1 - 7.8e-117 391.0 2.9 1.2e-116 390.4 2.0 1.1 1 0 0 1 1 1 1 Cohesin loading factor TPR_2 PF07719.12 KOS18642.1 - 0.24 11.3 0.1 0.24 11.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.17 KOS18643.1 - 4.6e-32 109.4 0.0 1.4e-15 56.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS18643.1 - 6.3e-20 70.9 0.0 3.6e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS18643.1 - 1.7e-15 56.5 0.0 3e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KOS18643.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 KOS18643.1 - 0.15 11.6 0.9 7.9 6.0 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain adh_short_C2 PF13561.1 KOS18644.1 - 1.3e-16 61.1 0.1 1.6e-16 60.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KOS18644.1 - 0.00097 19.0 0.1 0.0019 18.1 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase His_Phos_2 PF00328.17 KOS18645.1 - 0.00015 21.1 0.2 0.32 10.2 0.0 3.1 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 2) 3-HAO PF06052.7 KOS18646.1 - 2.7e-57 192.4 0.0 4.5e-56 188.4 0.0 2.0 1 1 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KOS18646.1 - 4e-08 32.6 0.0 5.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KOS18646.1 - 3.5e-05 23.5 0.0 6.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KOS18646.1 - 0.00053 19.4 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KOS18646.1 - 0.011 15.1 0.0 0.029 13.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) ARD PF03079.9 KOS18646.1 - 0.086 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cupin_4 PF08007.7 KOS18646.1 - 0.13 11.4 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein FYVE PF01363.16 KOS18646.1 - 1.1 9.1 3.7 3.6 7.5 2.7 1.8 1 1 0 1 1 1 0 FYVE zinc finger FAA_hydrolase PF01557.13 KOS18647.1 - 1.3e-52 178.3 0.0 1.5e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Cullin PF00888.17 KOS18648.1 - 1.7e-131 439.6 0.0 2.1e-131 439.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KOS18648.1 - 2.2e-25 88.2 0.1 6.6e-25 86.7 0.1 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain FAM86 PF14904.1 KOS18648.1 - 0.019 14.7 0.8 0.44 10.3 0.2 2.7 2 0 0 2 2 2 0 Family of unknown function NTase_sub_bind PF08780.6 KOS18648.1 - 0.033 13.9 0.2 1.6 8.5 0.0 3.0 2 0 0 2 2 2 0 Nucleotidyltransferase substrate binding protein like LSM PF01423.17 KOS18649.1 - 1.8e-16 59.3 0.0 2.5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KOS18649.1 - 0.00029 20.6 0.0 0.00043 20.1 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2763 PF10961.3 KOS18649.1 - 0.44 10.9 4.7 0.71 10.3 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Methyltransf_26 PF13659.1 KOS18650.1 - 5e-18 65.2 0.9 7e-18 64.7 0.6 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS18650.1 - 0.0027 17.1 0.0 0.0055 16.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain MinE PF03776.9 KOS18652.1 - 0.094 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE PKD_channel PF08016.7 KOS18652.1 - 0.42 8.9 9.1 2.1 6.6 1.0 2.3 2 0 0 2 2 2 0 Polycystin cation channel APH PF01636.18 KOS18653.1 - 1e-42 146.5 2.5 1.5e-42 145.9 1.7 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KOS18653.1 - 2.3e-05 23.6 0.0 6.1e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 KOS18653.1 - 0.0013 17.8 0.0 0.055 12.4 0.0 2.2 2 0 0 2 2 2 1 Fructosamine kinase Choline_kinase PF01633.15 KOS18653.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KOS18653.1 - 0.032 13.2 0.0 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KOS18653.1 - 0.15 11.3 0.0 4.2 6.6 0.0 2.2 2 0 0 2 2 2 0 RIO1 family ELMO_CED12 PF04727.8 KOS18654.1 - 2.2e-47 160.7 0.0 5.5e-47 159.4 0.0 1.6 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3361 PF11841.3 KOS18654.1 - 0.00023 20.9 0.1 0.0079 15.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Cyclin_N PF00134.18 KOS18655.1 - 3.7e-43 146.1 0.4 1.5e-42 144.1 0.1 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KOS18655.1 - 3.9e-34 117.0 0.1 1.2e-33 115.5 0.0 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain Nucleoplasmin PF03066.10 KOS18655.1 - 0.41 10.1 12.1 0.74 9.3 8.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 KOS18655.1 - 6.3 5.9 12.3 10 5.2 8.5 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 KOS18655.1 - 8 6.7 18.4 0.96 9.7 9.7 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 KOS18655.1 - 9 6.0 9.0 29 4.4 6.3 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal IF-2B PF01008.12 KOS18657.1 - 3.7e-43 147.5 0.1 1e-42 146.0 0.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family Anp1 PF03452.9 KOS18658.1 - 5.9e-111 369.9 0.0 7.3e-111 369.6 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 KOS18658.1 - 0.0072 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 RRM_1 PF00076.17 KOS18659.1 - 4.1e-05 23.1 0.0 9.6e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KOS18659.1 - 0.00061 20.1 9.5 0.00061 20.1 6.6 2.3 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 KOS18659.1 - 0.0046 16.7 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS18659.1 - 0.025 14.5 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MPLKIP PF15502.1 KOS18659.1 - 0.19 12.4 4.8 0.28 11.8 3.3 1.3 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein ICMT PF04140.9 KOS18660.1 - 1.9e-25 88.8 0.2 4.2e-25 87.7 0.2 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KOS18660.1 - 4.4e-12 46.0 1.0 4.4e-12 46.0 0.7 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 KOS18660.1 - 0.037 13.3 0.1 0.071 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Tmemb_170 PF10190.4 KOS18661.1 - 0.0002 21.3 10.9 0.00028 20.8 7.6 1.2 1 0 0 1 1 1 1 Putative transmembrane protein 170 DAG1 PF05454.6 KOS18661.1 - 0.18 10.9 0.9 0.33 10.1 0.1 1.7 1 1 1 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Endonuclease_NS PF01223.18 KOS18662.1 - 7e-58 195.6 0.0 9.2e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease ORC6 PF05460.8 KOS18662.1 - 0.62 9.1 5.0 0.87 8.6 3.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) WD40 PF00400.27 KOS18663.1 - 3.7e-49 162.9 22.4 5.5e-09 35.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KOS18663.1 - 0.0013 18.4 0.0 0.34 10.5 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KOS18663.1 - 0.0022 16.7 0.2 0.015 14.0 0.3 2.2 3 1 0 3 3 3 1 Nup133 N terminal like Arf PF00025.16 KOS18664.1 - 3.6e-66 221.6 0.0 4.1e-66 221.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KOS18664.1 - 1.7e-09 36.8 0.2 6.3e-06 25.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KOS18664.1 - 2.9e-08 34.2 0.0 4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KOS18664.1 - 8.8e-08 31.6 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KOS18664.1 - 2.9e-07 29.8 0.0 3.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KOS18664.1 - 2.9e-07 30.4 0.0 3.9e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KOS18664.1 - 1.1e-05 24.7 0.0 1.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KOS18664.1 - 0.0021 17.5 0.1 0.094 12.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain CENP-M PF11111.3 KOS18664.1 - 0.054 12.7 0.0 0.13 11.4 0.0 1.5 2 0 0 2 2 2 0 Centromere protein M (CENP-M) PduV-EutP PF10662.4 KOS18664.1 - 0.092 12.2 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pkinase PF00069.20 KOS18665.1 - 2.9e-52 177.4 0.0 3.8e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS18665.1 - 7.2e-37 126.8 0.0 9.9e-37 126.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS18665.1 - 0.0004 19.4 0.0 0.00083 18.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS18665.1 - 0.042 13.5 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.11 KOS18665.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.9 KOS18665.1 - 0.15 11.1 0.0 0.31 10.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2457 PF10446.4 KOS18666.1 - 7.6e-123 410.6 31.6 7.6e-123 410.6 21.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) ATP-synt_DE_N PF02823.11 KOS18668.1 - 4.1e-20 71.3 0.0 6.9e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Filament PF00038.16 KOS18670.1 - 0.0084 15.6 23.1 0.01 15.3 16.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein MFS_1 PF07690.11 KOS18671.1 - 1.7e-27 96.1 33.4 1.7e-27 96.1 23.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sds3 PF08598.6 KOS18673.1 - 1e-16 61.1 9.8 1e-16 61.1 6.8 3.4 2 2 0 2 2 2 1 Sds3-like RRM_1 PF00076.17 KOS18674.1 - 4.6e-10 39.0 1.8 1.2e-08 34.4 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS18674.1 - 4.9e-08 32.8 0.2 5.2e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS18674.1 - 6.2e-08 32.3 0.0 0.00071 19.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PBP1_TM PF14812.1 KOS18674.1 - 0.0031 17.7 21.5 0.0031 17.7 14.9 4.8 3 2 1 4 4 4 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3453 PF11935.3 KOS18675.1 - 1.8e-62 210.8 0.0 3.2e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Coiled-coil_56 PF09813.4 KOS18676.1 - 1.1e-05 25.3 0.0 1.1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Tubulin PF00091.20 KOS18677.1 - 8.9e-66 221.7 0.0 1.2e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KOS18677.1 - 9e-41 138.8 0.0 1.5e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KOS18677.1 - 0.0043 16.5 0.0 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF2723 PF11028.3 KOS18678.1 - 0.07 12.6 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) MerR-DNA-bind PF09278.6 KOS18678.1 - 0.076 13.4 1.3 0.076 13.4 0.9 1.9 2 0 0 2 2 2 0 MerR, DNA binding PRA1 PF03208.14 KOS18679.1 - 9.6e-37 125.6 1.1 1.2e-36 125.4 0.8 1.0 1 0 0 1 1 1 1 PRA1 family protein E1-E2_ATPase PF00122.15 KOS18679.1 - 0.1 11.5 0.9 0.14 11.1 0.6 1.1 1 0 0 1 1 1 0 E1-E2 ATPase VIT1 PF01988.14 KOS18679.1 - 0.27 10.6 3.3 0.38 10.2 2.3 1.1 1 0 0 1 1 1 0 VIT family DUF2516 PF10724.4 KOS18679.1 - 8.5 6.4 9.1 25 4.9 5.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2516) PEARLI-4 PF05278.7 KOS18680.1 - 0.0028 17.0 4.3 0.0048 16.3 3.0 1.4 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) PV-1 PF06637.6 KOS18680.1 - 0.087 11.3 4.1 0.12 10.9 2.9 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF3347 PF11827.3 KOS18680.1 - 0.18 11.7 5.3 0.3 11.0 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) eIF3_subunit PF08597.5 KOS18680.1 - 0.35 10.3 19.6 0.56 9.7 13.6 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CDC45 PF02724.9 KOS18680.1 - 2.2 6.1 17.0 3.8 5.4 11.8 1.4 1 0 0 1 1 1 0 CDC45-like protein UQ_con PF00179.21 KOS18681.1 - 5.7e-32 110.0 0.0 6.5e-32 109.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Dus PF01207.12 KOS18682.1 - 6.7e-44 149.9 0.2 1.7e-43 148.6 0.1 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.12 KOS18682.1 - 0.012 14.7 0.1 0.029 13.5 0.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Oxysterol_BP PF01237.13 KOS18684.1 - 1.9e-86 289.7 0.0 2.5e-86 289.3 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF2201_N PF13203.1 KOS18684.1 - 0.65 9.1 6.7 0.3 10.2 3.0 1.5 1 1 1 2 2 2 0 Putative metallopeptidase domain zf-CCCH PF00642.19 KOS18685.1 - 1.7e-08 33.9 18.1 4.6e-07 29.3 1.6 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KOS18685.1 - 7.2e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS18685.1 - 0.0034 16.9 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tachystatin_B PF11478.3 KOS18685.1 - 4.3 7.1 9.0 0.4 10.4 1.3 2.6 3 0 0 3 3 3 0 Antimicrobial chitin binding protein tachystatin B DUF410 PF04190.8 KOS18686.1 - 7e-51 173.2 0.0 8.2e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF1059 PF06348.6 KOS18687.1 - 0.063 13.1 0.6 0.45 10.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) DUF2984 PF11203.3 KOS18688.1 - 0.038 14.0 0.1 0.26 11.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) NPCC PF08058.6 KOS18689.1 - 3e-27 95.2 0.0 5.2e-26 91.2 0.0 2.1 1 1 0 1 1 1 1 Nuclear pore complex component NmrA PF05368.8 KOS18690.1 - 3.1e-76 255.7 0.0 3.8e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KOS18690.1 - 5.6e-05 23.2 0.2 0.0045 17.0 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding ERG2_Sigma1R PF04622.7 KOS18691.1 - 1.6e-95 318.4 0.0 1.8e-95 318.3 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Fcf1 PF04900.7 KOS18692.1 - 1.4e-37 127.8 0.1 2.8e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 Fcf1 Fungal_trans PF04082.13 KOS18693.1 - 3.3e-13 49.1 0.5 5.8e-13 48.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS18693.1 - 1.7e-06 27.7 10.6 3.1e-06 26.9 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rep_fac_C PF08542.6 KOS18695.1 - 1.8e-20 72.6 0.2 6.1e-20 71.0 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KOS18695.1 - 2e-11 43.7 0.0 1.5e-09 37.7 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KOS18695.1 - 3.1e-11 43.5 0.0 6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KOS18695.1 - 2.1e-07 30.8 0.0 4.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS18695.1 - 2.8e-06 27.4 0.0 5.6e-05 23.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KOS18695.1 - 4.2e-06 25.9 0.0 1.6e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 KOS18695.1 - 1.3e-05 24.1 0.0 0.023 13.4 0.0 2.8 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KOS18695.1 - 2.3e-05 24.5 0.1 0.029 14.5 0.0 2.7 2 1 1 3 3 2 2 AAA domain AAA_3 PF07726.6 KOS18695.1 - 0.00011 21.7 0.0 0.00025 20.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KOS18695.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 KOS18695.1 - 0.00038 20.0 0.0 0.045 13.1 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain AAA_19 PF13245.1 KOS18695.1 - 0.002 17.8 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 KOS18695.1 - 0.0036 16.4 0.0 0.026 13.6 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.8 KOS18695.1 - 0.0036 16.8 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_25 PF13481.1 KOS18695.1 - 0.0041 16.5 0.0 0.067 12.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain DEAD PF00270.24 KOS18695.1 - 0.0047 16.4 0.1 0.21 11.0 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 KOS18695.1 - 0.0062 16.0 0.1 0.017 14.6 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family NTPase_1 PF03266.10 KOS18695.1 - 0.0062 16.2 0.2 0.031 13.9 0.1 2.1 1 1 1 2 2 2 1 NTPase ArgK PF03308.11 KOS18695.1 - 0.0069 15.2 0.0 0.018 13.8 0.0 1.5 1 1 0 1 1 1 1 ArgK protein DNA_pol3_gamma3 PF12169.3 KOS18695.1 - 0.013 15.2 0.4 0.83 9.4 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III AAA_11 PF13086.1 KOS18695.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 KOS18695.1 - 0.017 14.3 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 KOS18695.1 - 0.019 15.2 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 KOS18695.1 - 0.021 14.7 0.0 0.069 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KOS18695.1 - 0.11 12.1 0.2 0.49 10.1 0.0 2.1 3 1 0 3 3 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KOS18695.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain IKI3 PF04762.7 KOS18696.1 - 1.7e-268 893.2 0.0 3.7e-226 753.1 0.0 2.0 1 1 1 2 2 2 2 IKI3 family TPR_8 PF13181.1 KOS18696.1 - 0.27 11.1 1.1 1.1 9.2 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Lamp PF01299.12 KOS18696.1 - 0.29 10.2 0.0 0.49 9.4 0.0 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) S-AdoMet_synt_C PF02773.11 KOS18697.1 - 1.9e-74 247.8 0.3 3.5e-74 247.0 0.2 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KOS18697.1 - 1.5e-46 157.2 0.0 2.5e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KOS18697.1 - 7.3e-42 141.6 0.4 1.9e-41 140.3 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain ATP_bind_1 PF03029.12 KOS18698.1 - 5e-72 242.2 0.0 6.2e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KOS18698.1 - 3.3e-05 24.6 0.1 9.9e-05 23.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KOS18698.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KOS18698.1 - 0.0032 16.9 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_31 PF13614.1 KOS18698.1 - 0.0054 16.6 0.0 0.055 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KOS18698.1 - 0.0058 16.6 0.0 0.099 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KOS18698.1 - 0.0071 16.2 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KOS18698.1 - 0.0088 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_10 PF12846.2 KOS18698.1 - 0.012 15.0 0.0 0.044 13.2 0.0 1.9 1 1 1 2 2 2 0 AAA-like domain AAA_22 PF13401.1 KOS18698.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 KOS18698.1 - 0.031 13.7 0.0 5.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KOS18698.1 - 0.032 14.1 0.0 0.1 12.5 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KOS18698.1 - 0.038 14.2 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 KOS18698.1 - 0.04 13.6 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KOS18698.1 - 0.058 12.7 0.0 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KOS18698.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KOS18698.1 - 0.12 12.7 0.1 0.6 10.4 0.0 2.3 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.17 KOS18698.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KOS18698.1 - 0.14 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain PI-PLC-X PF00388.14 KOS18699.1 - 3.4e-07 29.7 0.0 5.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain MaoC_dehydratas PF01575.14 KOS18701.1 - 1.2e-20 73.0 0.0 2e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KOS18701.1 - 3.5e-08 33.3 0.0 1.6e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase ERp29_N PF07912.8 KOS18701.1 - 0.047 13.6 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 ERp29, N-terminal domain DUF1349 PF07081.6 KOS18703.1 - 5.3e-24 84.5 0.0 3.2e-11 42.9 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1349) DUF3328 PF11807.3 KOS18703.1 - 0.018 14.7 0.2 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) CAP_GLY PF01302.20 KOS18704.1 - 6.6e-19 67.3 0.0 1.3e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 KOS18704.1 - 4.9e-17 61.1 3.5 0.00017 21.1 1.5 5.9 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS18704.1 - 2.3e-12 46.4 1.5 0.0014 18.2 0.9 4.7 5 0 0 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 KOS18704.1 - 3.3e-05 23.3 11.8 12 6.3 0.0 7.2 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.1 KOS18704.1 - 3.7e-05 23.3 11.1 10 6.5 0.0 7.7 8 0 0 8 8 8 1 Leucine Rich repeat LRR_9 PF14580.1 KOS18704.1 - 0.025 14.1 0.1 1.2 8.7 0.0 3.1 3 1 1 4 4 4 0 Leucine-rich repeat LRR_7 PF13504.1 KOS18704.1 - 0.03 14.4 8.3 51 4.7 0.1 6.6 7 0 0 7 7 7 0 Leucine rich repeat ATP-synt_E PF05680.7 KOS18705.1 - 7.5e-21 73.8 0.7 8.7e-21 73.6 0.5 1.1 1 0 0 1 1 1 1 ATP synthase E chain Trypan_glycop PF00913.14 KOS18705.1 - 0.029 13.3 1.2 0.035 13.0 0.8 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) ABC_trans_N PF14510.1 KOS18705.1 - 0.046 13.8 0.3 0.062 13.4 0.2 1.3 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal Atg14 PF10186.4 KOS18705.1 - 0.23 10.3 2.5 0.27 10.1 1.7 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Drf_GBD PF06371.8 KOS18705.1 - 0.29 10.4 2.1 0.32 10.3 1.5 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain WD40 PF00400.27 KOS18706.1 - 1.1e-21 75.7 6.3 1.4e-07 31.0 0.1 6.5 8 0 0 8 8 8 5 WD domain, G-beta repeat TIM PF00121.13 KOS18708.1 - 9e-88 293.4 0.2 1e-87 293.2 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Toprim PF01751.17 KOS18708.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Toprim domain CutC PF03932.9 KOS18708.1 - 0.084 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 CutC family L51_S25_CI-B8 PF05047.11 KOS18709.1 - 2e-15 56.2 0.0 3.2e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF187 PF02638.10 KOS18709.1 - 0.049 12.4 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 U1snRNP70_N PF12220.3 KOS18710.1 - 1.8e-29 101.8 3.1 1.8e-29 101.8 2.1 1.5 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 KOS18710.1 - 9.3e-11 41.2 0.1 6.7e-10 38.4 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS18710.1 - 1.8e-07 31.0 0.0 3.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS18710.1 - 0.018 14.9 0.5 0.064 13.1 0.3 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.15 KOS18711.1 - 2.8e-19 68.8 0.0 4.3e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 NTF2 PF02136.15 KOS18712.1 - 4.6e-23 81.8 0.2 7.6e-23 81.1 0.2 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KOS18712.1 - 1.4e-05 24.5 0.0 2.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS18712.1 - 7.4e-05 22.6 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS18712.1 - 0.0082 15.9 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_31 PF13847.1 KOS18712.1 - 0.052 13.1 0.4 0.098 12.2 0.3 1.4 1 0 0 1 1 1 0 Methyltransferase domain RRM_3 PF08777.6 KOS18712.1 - 0.11 12.3 2.5 0.22 11.3 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif FAST_2 PF08368.7 KOS18712.1 - 0.2 12.0 1.0 0.5 10.7 0.7 1.6 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 DUF2232 PF09991.4 KOS18712.1 - 0.79 8.6 1.8 1.1 8.1 1.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Daxx PF03344.10 KOS18712.1 - 7.6 4.8 17.9 10 4.4 12.4 1.1 1 0 0 1 1 1 0 Daxx Family PH_9 PF15410.1 KOS18713.1 - 1.4e-08 34.8 0.0 2.1e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KOS18713.1 - 0.00043 20.4 0.1 0.0034 17.5 0.0 2.0 2 0 0 2 2 2 1 PH domain DUF2360 PF10152.4 KOS18713.1 - 0.034 14.4 0.2 0.068 13.4 0.1 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Pex14_N PF04695.8 KOS18713.1 - 0.18 11.8 5.7 4.2 7.4 3.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nnf1 PF03980.9 KOS18714.1 - 3.9e-21 75.0 0.2 3.9e-21 75.0 0.1 3.7 4 1 0 4 4 2 1 Nnf1 BLVR PF06375.6 KOS18714.1 - 0.011 15.5 8.3 0.019 14.8 5.8 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Med15 PF09606.5 KOS18714.1 - 0.024 12.8 25.5 0.028 12.6 17.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 KOS18714.1 - 0.055 12.9 15.5 0.1 12.0 10.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AUX_IAA PF02309.11 KOS18714.1 - 0.16 11.6 5.8 0.23 11.2 4.0 1.3 1 0 0 1 1 1 0 AUX/IAA family Nop53 PF07767.6 KOS18714.1 - 0.16 10.9 17.8 0.088 11.7 10.3 1.9 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Ndc1_Nup PF09531.5 KOS18714.1 - 0.17 10.2 8.2 0.18 10.1 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF702 PF05142.7 KOS18714.1 - 0.18 11.9 8.7 0.35 11.0 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) NST1 PF13945.1 KOS18714.1 - 0.19 11.7 15.5 0.33 10.9 10.7 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator eIF3_subunit PF08597.5 KOS18714.1 - 0.37 10.3 14.4 0.73 9.3 9.9 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit BRF1 PF07741.8 KOS18714.1 - 0.74 10.0 12.2 1.6 9.0 8.4 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Pex14_N PF04695.8 KOS18714.1 - 0.82 9.7 11.5 1.8 8.6 7.9 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dicty_REP PF05086.7 KOS18714.1 - 0.94 7.1 3.1 1 7.0 2.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NARP1 PF12569.3 KOS18714.1 - 1.5 7.5 17.0 1.2 7.7 9.5 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.5 KOS18714.1 - 1.8 8.3 11.1 4.5 7.0 7.7 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DDRGK PF09756.4 KOS18714.1 - 2 7.7 17.9 4.4 6.6 12.4 1.5 1 0 0 1 1 1 0 DDRGK domain YqfQ PF14181.1 KOS18714.1 - 2.4 8.2 15.5 4.7 7.2 10.7 1.4 1 0 0 1 1 1 0 YqfQ-like protein Baculo_PP31 PF05311.6 KOS18714.1 - 3 7.0 15.3 4.8 6.3 10.6 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FLO_LFY PF01698.11 KOS18714.1 - 3.7 6.3 11.6 6.7 5.4 8.0 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Borrelia_P83 PF05262.6 KOS18714.1 - 3.7 5.7 11.4 4.2 5.5 7.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PAT1 PF09770.4 KOS18714.1 - 5.8 5.0 30.7 7.6 4.6 21.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.9 KOS18714.1 - 6.4 4.6 13.4 9.6 4.1 9.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1764 PF08576.5 KOS18714.1 - 8.3 7.2 14.9 20 6.0 10.3 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) SOBP PF15279.1 KOS18714.1 - 8.6 6.6 17.4 11 6.2 11.8 1.4 1 1 0 1 1 1 0 Sine oculis-binding protein IncA PF04156.9 KOS18714.1 - 10 5.6 15.6 10 5.6 0.0 2.4 2 0 0 2 2 2 0 IncA protein DUF1640 PF07798.6 KOS18715.1 - 8.9e-12 45.4 4.9 8.9e-12 45.4 3.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) Mucin PF01456.12 KOS18715.1 - 0.0071 16.1 16.4 0.014 15.1 11.3 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein Phage_connect_1 PF05135.8 KOS18715.1 - 0.091 12.9 0.0 0.091 12.9 0.0 2.3 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein SSP160 PF06933.6 KOS18715.1 - 0.73 7.7 17.7 1.3 6.8 12.3 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PUF PF00806.14 KOS18716.1 - 3.4e-62 202.5 6.7 1.3e-08 33.8 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 KOS18716.1 - 0.0012 19.0 1.7 0.21 11.8 0.0 3.1 3 1 0 3 3 3 1 Protein of unknown function DUF260 CTD_bind PF04818.8 KOS18716.1 - 0.024 14.8 0.9 1.6 9.0 0.0 3.6 2 1 0 3 3 3 0 RNA polymerase II-binding domain. Methyltransf_8 PF05148.10 KOS18716.1 - 0.041 13.4 0.8 0.07 12.7 0.5 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase MgtE_N PF03448.12 KOS18716.1 - 0.12 12.7 3.1 11 6.4 0.0 3.3 4 0 0 4 4 4 0 MgtE intracellular N domain IpaB_EvcA PF03278.8 KOS18716.1 - 0.21 10.8 2.9 3.2 6.9 0.1 3.1 2 2 1 3 3 3 0 IpaB/EvcA family DUF234 PF03008.9 KOS18716.1 - 0.4 10.8 3.1 0.96 9.6 0.2 2.6 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function Mg_trans_NIPA PF05653.9 KOS18717.1 - 3.5e-104 347.9 11.5 4.1e-104 347.7 8.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KOS18717.1 - 5.9e-08 32.8 3.8 5.9e-08 32.8 2.6 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KOS18717.1 - 0.00015 21.7 7.1 0.00015 21.7 4.9 3.4 3 1 1 4 4 4 1 EamA-like transporter family Ribosomal_S3_C PF00189.15 KOS18718.1 - 1.2e-16 60.6 0.1 2.4e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KOS18718.1 - 2.6e-12 46.1 0.1 4.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 KOS18718.1 - 0.057 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Abhydrolase_2 PF02230.11 KOS18719.1 - 2.1e-44 151.5 0.0 2.4e-31 108.8 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KOS18719.1 - 4.1e-11 42.8 0.0 2e-10 40.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS18719.1 - 4.8e-08 33.1 0.0 5.2e-06 26.5 0.0 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 KOS18719.1 - 1.2e-05 24.8 0.0 2.9e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 KOS18719.1 - 0.063 12.7 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Cutinase PF01083.17 KOS18719.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.8 KOS18719.1 - 0.088 12.3 0.0 1.3 8.5 0.0 2.2 2 1 1 3 3 3 0 alpha/beta hydrolase fold Adap_comp_sub PF00928.16 KOS18720.1 - 1.1e-14 54.2 0.0 1.8e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KOS18720.1 - 1.1e-07 31.6 0.3 2.1e-07 30.7 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KOS18720.1 - 0.00014 21.1 0.0 0.00079 18.6 0.0 2.0 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain RPM2 PF08579.6 KOS18720.1 - 0.022 14.9 0.4 0.048 13.7 0.3 1.6 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) Qn_am_d_aII PF14930.1 KOS18720.1 - 0.14 12.0 0.1 0.38 10.7 0.0 1.7 1 1 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Phage_glycop_gL PF11108.3 KOS18721.1 - 0.024 14.6 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Viral glycoprotein L MIT PF04212.13 KOS18721.1 - 0.13 12.1 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Myotub-related PF06602.9 KOS18723.1 - 3.2e-118 394.5 0.1 4.6e-118 394.0 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 KOS18723.1 - 0.047 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family B3_4 PF03483.12 KOS18724.1 - 1.8e-23 82.9 0.0 3e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KOS18724.1 - 5.8e-15 54.8 0.0 3.2e-11 42.9 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain UQ_con PF00179.21 KOS18725.1 - 7.3e-25 87.0 0.0 9e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS18725.1 - 2.2e-07 30.6 0.0 2.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KOS18725.1 - 0.00012 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 KOS18725.1 - 0.00014 21.6 0.1 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain Sec1 PF00995.18 KOS18726.1 - 6.3e-134 447.6 0.0 7.2e-134 447.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DGCR6 PF07324.6 KOS18726.1 - 0.011 15.1 0.9 0.29 10.6 0.2 2.6 2 0 0 2 2 2 0 DiGeorge syndrome critical region 6 (DGCR6) protein PGAP1 PF07819.8 KOS18727.1 - 4.4e-05 23.1 0.1 0.00016 21.3 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 KOS18727.1 - 0.00027 20.3 0.0 0.00042 19.6 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KOS18727.1 - 0.00031 20.7 0.1 0.00038 20.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS18727.1 - 0.0082 15.9 0.0 0.023 14.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family GLTT PF01744.15 KOS18727.1 - 1.2 8.5 3.8 0.33 10.4 0.3 1.8 2 0 0 2 2 2 0 GLTT repeat (6 copies) Pkinase PF00069.20 KOS18730.1 - 9.5e-71 237.9 0.0 1.3e-70 237.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS18730.1 - 9.9e-35 119.8 0.0 1.4e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS18730.1 - 6.6e-05 22.0 0.0 0.00013 21.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KOS18730.1 - 0.00048 19.5 0.2 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KOS18730.1 - 0.0042 16.1 0.0 0.0088 15.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_6 PF12697.2 KOS18731.1 - 1.4e-24 87.2 4.3 2.3e-24 86.5 3.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS18731.1 - 3.9e-12 46.1 0.1 1.2e-11 44.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS18731.1 - 1.1e-07 31.6 0.3 2.8e-06 27.0 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KOS18731.1 - 9e-05 22.2 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase UPF0227 PF05728.7 KOS18731.1 - 0.0021 17.8 0.1 0.37 10.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Esterase PF00756.15 KOS18731.1 - 0.0023 17.3 0.5 0.0037 16.7 0.3 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.13 KOS18731.1 - 0.0024 17.1 0.0 0.13 11.4 0.0 2.6 2 1 0 2 2 2 1 Dienelactone hydrolase family Lipase_3 PF01764.20 KOS18731.1 - 0.0042 16.7 0.1 0.0094 15.5 0.1 1.6 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 KOS18731.1 - 0.048 13.8 0.9 5.8 7.0 0.2 2.3 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.8 KOS18731.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ndr PF03096.9 KOS18731.1 - 0.23 9.9 0.1 0.43 9.0 0.1 1.5 1 1 0 1 1 1 0 Ndr family tRNA-synt_His PF13393.1 KOS18732.1 - 3.2e-39 134.8 0.0 9.5e-33 113.5 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KOS18732.1 - 5.1e-19 68.5 0.0 7.4e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KOS18732.1 - 9.4e-13 47.9 0.0 1.9e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KOS18732.1 - 0.00047 19.0 0.1 0.016 14.0 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Ribosomal_60s PF00428.14 KOS18732.1 - 0.0031 17.8 1.2 0.01 16.2 0.8 1.8 1 0 0 1 1 1 1 60s Acidic ribosomal protein C2 PF00168.25 KOS18733.1 - 5.4e-69 228.0 2.3 4.4e-21 74.5 0.0 5.4 5 0 0 5 5 5 5 C2 domain DUF4429 PF14472.1 KOS18733.1 - 0.024 14.9 0.0 0.095 13.0 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4429) B56 PF01603.15 KOS18733.1 - 0.49 8.9 0.0 0.75 8.3 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) zf-RING_2 PF13639.1 KOS18734.1 - 2e-07 30.6 10.7 6.2e-07 29.1 2.3 2.5 2 1 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 KOS18734.1 - 0.0006 19.8 8.2 0.039 14.0 3.9 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KOS18734.1 - 0.015 14.9 2.1 0.015 14.9 1.5 2.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS18734.1 - 0.023 14.7 10.3 0.039 13.9 2.5 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KOS18734.1 - 0.038 13.9 5.1 0.42 10.6 2.4 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 KOS18734.1 - 0.06 13.3 3.0 0.18 11.8 0.8 2.4 2 1 0 2 2 2 0 RING-variant domain zf-C3HC4_3 PF13920.1 KOS18734.1 - 0.35 10.5 5.0 11 5.8 1.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KOS18734.1 - 0.84 9.5 4.3 80 3.1 0.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KOS18734.1 - 2.1 8.1 7.5 0.22 11.2 1.0 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.1 KOS18734.1 - 5 6.9 9.8 9.1 6.1 0.2 2.6 2 1 1 3 3 3 0 zinc-RING finger domain WD40 PF00400.27 KOS18735.1 - 4.3e-15 54.9 0.5 0.00037 20.2 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF702 PF05142.7 KOS18735.1 - 1.3 9.2 5.0 0.76 9.9 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF3439 PF11921.3 KOS18735.1 - 1.8 8.3 11.6 3.9 7.2 8.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) INSIG PF07281.7 KOS18736.1 - 1.3e-34 119.2 2.7 6.6e-34 116.9 1.9 1.9 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) DUF4131 PF13567.1 KOS18736.1 - 0.34 10.3 9.9 0.31 10.4 0.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) BAF1_ABF1 PF04684.8 KOS18737.1 - 0.65 8.7 5.2 1 8.1 3.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Evr1_Alr PF04777.8 KOS18738.1 - 5.8e-29 99.8 0.0 8.1e-29 99.3 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family DUF3594 PF12165.3 KOS18738.1 - 0.11 12.1 0.1 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3594) Proteasome PF00227.21 KOS18739.1 - 3.3e-47 160.2 0.2 3.8e-47 160.0 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.6 KOS18740.1 - 2.6e-40 138.2 0.3 1.7e-23 83.7 0.0 2.2 2 0 0 2 2 2 2 Cyclin Serglycin PF04360.7 KOS18740.1 - 4.4e-05 23.2 0.7 0.0024 17.6 0.2 2.3 2 0 0 2 2 2 2 Serglycin DUF1640 PF07798.6 KOS18742.1 - 1e-65 221.0 7.9 1.2e-65 220.8 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) cwf21 PF08312.7 KOS18742.1 - 0.0041 16.9 2.9 0.029 14.2 0.5 2.6 2 1 0 2 2 2 1 cwf21 domain Lzipper-MIP1 PF14389.1 KOS18742.1 - 0.0079 16.2 3.7 1.6 8.8 0.0 2.6 2 0 0 2 2 2 2 Leucine-zipper of ternary complex factor MIP1 Metal_resist PF13801.1 KOS18742.1 - 0.014 15.4 3.9 0.014 15.4 2.7 1.9 2 0 0 2 2 2 0 Heavy-metal resistance CLAMP PF14769.1 KOS18742.1 - 0.098 12.8 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 SSFA2_C PF14723.1 KOS18742.1 - 0.2 11.4 3.9 0.28 10.8 2.7 1.5 1 1 0 1 1 1 0 Sperm-specific antigen 2 C-terminus Syntaxin PF00804.20 KOS18742.1 - 0.77 9.9 9.6 0.91 9.7 3.9 2.5 1 1 2 3 3 3 0 Syntaxin FTA4 PF13093.1 KOS18742.1 - 5.3 6.4 9.3 14 4.9 6.5 1.6 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TPR_11 PF13414.1 KOS18743.1 - 2.9e-20 71.6 11.4 1.7e-06 27.5 0.6 6.1 5 1 2 7 7 7 4 TPR repeat TPR_2 PF07719.12 KOS18743.1 - 3.2e-14 51.6 23.1 0.032 14.1 0.0 10.0 10 1 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 KOS18743.1 - 2.4e-11 42.5 0.0 0.0076 15.9 0.1 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KOS18743.1 - 1.5e-10 40.8 17.8 0.00029 20.7 0.2 7.4 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS18743.1 - 1.5e-10 41.2 14.2 0.00075 19.7 1.3 6.7 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 KOS18743.1 - 3.2e-09 35.9 10.4 0.069 12.7 0.0 7.3 9 0 0 9 9 8 2 Tetratricopeptide repeat Apc3 PF12895.2 KOS18743.1 - 7.7e-09 35.5 0.2 0.00065 19.7 0.0 4.2 3 2 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KOS18743.1 - 3e-08 33.6 47.6 0.0023 18.4 0.3 10.5 5 2 6 11 11 10 4 Tetratricopeptide repeat TPR_17 PF13431.1 KOS18743.1 - 3.4e-08 33.0 0.2 1.6 9.1 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS18743.1 - 1.8e-07 30.4 5.8 0.12 12.2 0.1 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KOS18743.1 - 1e-06 29.2 17.1 4.5e-06 27.1 4.3 8.9 7 2 3 10 10 8 6 Tetratricopeptide repeat TPR_15 PF13429.1 KOS18743.1 - 2.7e-06 26.6 7.0 4.5e-05 22.6 3.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KOS18743.1 - 0.016 15.6 15.8 0.49 10.9 0.1 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF3856 PF12968.2 KOS18743.1 - 0.1 12.4 2.3 0.71 9.6 0.3 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) Serglycin PF04360.7 KOS18743.1 - 1.8 8.2 4.0 8.9 6.0 0.1 2.2 2 0 0 2 2 2 0 Serglycin Globin PF00042.17 KOS18745.1 - 2.8e-08 34.0 0.0 4.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.19 KOS18745.1 - 4.6e-07 29.8 0.0 0.00072 19.6 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KOS18745.1 - 4.8e-06 27.1 0.0 1.2e-05 25.7 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KOS18745.1 - 0.011 15.6 0.0 0.067 13.1 0.0 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DUF461 PF04314.8 KOS18745.1 - 0.075 12.7 0.1 17 5.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF461) HET PF06985.6 KOS18747.1 - 1.7e-21 76.8 9.6 3.2e-19 69.4 1.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Terpene_synth_C PF03936.11 KOS18748.1 - 0.014 14.6 0.0 0.035 13.3 0.0 1.7 1 1 0 1 1 1 0 Terpene synthase family, metal binding domain AA_permease PF00324.16 KOS18749.1 - 2e-126 422.1 45.0 2.4e-126 421.9 31.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KOS18749.1 - 5.4e-36 124.0 48.7 6.3e-36 123.8 33.7 1.1 1 0 0 1 1 1 1 Amino acid permease Renin_r PF07850.9 KOS18749.1 - 0.77 10.1 0.0 0.77 10.1 0.0 3.1 4 0 0 4 4 4 0 Renin receptor-like protein ADH_N PF08240.7 KOS18750.1 - 5.2e-15 55.1 0.0 9.4e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KOS18750.1 - 6.1e-12 45.2 4.6 6.9e-09 35.3 0.4 2.8 3 0 0 3 3 3 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KOS18750.1 - 9.3e-05 21.6 0.5 0.00015 20.9 0.4 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 KOS18750.1 - 0.00034 21.4 0.1 0.0011 19.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KOS18750.1 - 0.0069 15.9 2.1 0.011 15.3 1.5 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KOS18750.1 - 0.09 12.4 0.8 0.13 11.8 0.6 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 KOS18750.1 - 0.45 10.3 3.4 0.74 9.6 2.4 1.3 1 0 0 1 1 1 0 ThiF family Glyco_hydro_49 PF03718.8 KOS18751.1 - 4.6e-185 616.0 13.4 5.2e-185 615.8 9.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 Metallophos_C PF14008.1 KOS18754.1 - 7.9e-12 45.0 0.1 1.7e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 KOS18754.1 - 1.2e-11 44.3 0.0 9.9e-11 41.3 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.5 KOS18754.1 - 0.0037 15.8 0.0 0.0085 14.6 0.0 1.5 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 KOS18754.1 - 0.034 13.9 0.0 0.091 12.5 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain AIG2 PF06094.7 KOS18755.1 - 1.6e-13 51.0 0.1 2.1e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 AIG2-like family Sec8_exocyst PF04048.9 KOS18756.1 - 6.2e-47 158.7 0.8 1.8e-46 157.3 0.5 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KOS18756.1 - 1.6e-10 40.3 2.1 3e-10 39.4 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 KOS18756.1 - 0.0015 18.2 1.3 0.0034 17.1 0.9 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec5 IZUMO PF15005.1 KOS18756.1 - 0.13 12.3 0.8 0.43 10.6 0.1 2.3 3 0 0 3 3 3 0 Izumo sperm-egg fusion Hid1 PF12722.2 KOS18757.1 - 3.4e-221 736.5 0.0 1.3e-190 635.2 0.0 3.1 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KOS18757.1 - 7.2e-60 202.8 0.0 9.3e-60 202.5 0.0 1.3 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Daxx PF03344.10 KOS18757.1 - 0.022 13.2 8.6 0.031 12.7 6.0 1.1 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 KOS18757.1 - 1.5 8.2 5.9 2.6 7.5 4.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 KOS18757.1 - 2.5 7.6 6.9 4.2 6.9 4.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 KOS18757.1 - 7.5 5.7 5.8 13 4.9 4.1 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 KOS18757.1 - 8.1 4.2 9.0 12 3.6 6.3 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KOS18757.1 - 8.4 4.2 5.2 12 3.7 3.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RCC1_2 PF13540.1 KOS18758.1 - 2.6e-12 46.0 16.1 7.8e-08 31.7 0.8 4.4 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 KOS18758.1 - 4e-08 33.3 21.2 0.11 12.7 7.2 5.7 5 2 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat AAA_17 PF13207.1 KOS18759.1 - 1.1e-07 32.6 0.1 5.4e-07 30.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KOS18759.1 - 9.2e-05 22.7 0.0 0.0006 20.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain CPT PF07931.7 KOS18759.1 - 0.00034 20.2 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 KOS18759.1 - 0.004 17.1 0.0 0.0088 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain PRK PF00485.13 KOS18759.1 - 0.012 15.1 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 KOS18759.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Protocadherin PF08374.6 KOS18761.1 - 0.021 14.4 0.1 0.035 13.7 0.1 1.3 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.1 KOS18761.1 - 0.027 14.1 0.1 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family NCU-G1 PF15065.1 KOS18761.1 - 0.17 10.5 0.1 0.24 10.0 0.1 1.1 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 Zn_clus PF00172.13 KOS18762.1 - 2.1e-13 49.9 29.6 1.5e-07 31.1 8.8 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KOS18762.1 - 2.3e-11 43.0 0.2 3.5e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Haem_bd PF14376.1 KOS18762.1 - 0.14 11.8 2.1 0.32 10.6 1.4 1.6 1 0 0 1 1 1 0 Haem-binding domain zf-C2H2 PF00096.21 KOS18764.1 - 1.1e-06 28.5 18.1 1.2e-05 25.3 2.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KOS18764.1 - 1.9e-05 24.6 2.6 1.9e-05 24.6 1.8 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KOS18764.1 - 0.0002 21.3 0.5 0.0002 21.3 0.4 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KOS18764.1 - 0.00043 20.4 0.6 0.00043 20.4 0.4 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 KOS18764.1 - 0.004 17.2 2.9 0.031 14.4 0.4 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF629 PF04780.7 KOS18764.1 - 0.038 12.5 2.5 0.6 8.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.1 KOS18764.1 - 0.052 13.4 0.6 0.64 10.0 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger ARS2 PF04959.8 KOS18764.1 - 0.095 12.8 3.0 0.33 11.1 1.5 2.4 2 1 0 2 2 2 0 Arsenite-resistance protein 2 Stb3 PF10330.4 KOS18765.1 - 1.2e-35 121.0 0.0 2.1e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein Topoisom_bac PF01131.15 KOS18766.1 - 2e-91 306.8 0.0 1.2e-86 291.0 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 KOS18766.1 - 6.9e-18 64.4 0.0 1.8e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.1 KOS18766.1 - 0.09 12.7 0.1 1 9.4 0.0 2.7 3 0 0 3 3 3 0 Toprim domain DUF1295 PF06966.7 KOS18767.1 - 1e-39 136.2 6.7 1.2e-39 135.9 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 KOS18767.1 - 0.1 12.8 1.3 0.35 11.0 0.0 2.4 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Hydrolase_6 PF13344.1 KOS18768.1 - 3.3e-16 59.0 0.0 5.8e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KOS18768.1 - 1.8e-09 37.1 0.0 4.4e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KOS18768.1 - 9.6e-06 26.1 0.0 0.00035 21.0 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CDC27 PF09507.5 KOS18769.1 - 0.073 12.2 5.7 0.089 12.0 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TPR_11 PF13414.1 KOS18770.1 - 4.2e-40 135.2 26.6 2.4e-12 46.2 1.4 8.4 5 2 3 9 9 9 8 TPR repeat TPR_1 PF00515.23 KOS18770.1 - 1.4e-38 128.9 22.2 1.1e-07 31.1 0.2 10.3 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_2 PF07719.12 KOS18770.1 - 4.1e-37 123.0 28.7 2.6e-06 26.8 0.1 11.3 12 0 0 12 12 12 7 Tetratricopeptide repeat Apc3 PF12895.2 KOS18770.1 - 7.3e-31 106.1 13.6 1.3e-20 73.2 0.0 5.0 5 0 0 5 5 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KOS18770.1 - 9.6e-29 99.4 29.6 1.9e-09 37.9 1.0 8.2 7 1 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 KOS18770.1 - 1.9e-25 86.6 8.7 0.0025 17.4 0.0 10.8 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 KOS18770.1 - 2.6e-25 88.5 18.6 5.1e-05 23.5 2.5 7.2 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KOS18770.1 - 5.9e-25 85.4 28.5 0.0031 18.0 0.8 11.1 5 3 6 11 11 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 KOS18770.1 - 3.7e-24 84.4 27.5 2.2e-06 27.5 2.0 8.3 5 3 4 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 KOS18770.1 - 1.4e-19 68.6 15.4 0.00074 19.5 0.2 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 KOS18770.1 - 1e-17 62.4 17.5 0.0027 17.3 0.0 8.7 9 0 0 9 9 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 KOS18770.1 - 2.6e-10 40.0 29.7 0.0076 16.6 0.0 10.8 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_15 PF13429.1 KOS18770.1 - 3.8e-07 29.4 15.7 0.012 14.7 1.8 5.1 3 2 1 4 4 4 3 Tetratricopeptide repeat YfiO PF13525.1 KOS18770.1 - 0.00018 21.0 2.1 0.27 10.6 0.1 3.4 3 0 0 3 3 3 2 Outer membrane lipoprotein TPR_4 PF07721.9 KOS18770.1 - 0.00021 21.4 15.4 0.15 12.5 0.1 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 KOS18770.1 - 0.00074 19.3 19.3 0.29 11.0 0.0 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.1 KOS18770.1 - 0.0037 17.3 7.6 0.037 14.1 1.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TOM20_plant PF06552.7 KOS18770.1 - 0.014 14.9 1.1 8.4 5.9 0.0 3.9 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 MIT PF04212.13 KOS18770.1 - 0.017 14.9 5.0 2.2 8.2 0.0 4.0 3 1 1 4 4 3 0 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 KOS18770.1 - 0.039 13.4 1.2 2.4 7.5 0.1 3.2 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) APP_E2 PF12925.2 KOS18770.1 - 0.043 13.3 3.8 26 4.3 0.1 3.8 1 1 2 3 3 3 0 E2 domain of amyloid precursor protein Fis1_TPR_C PF14853.1 KOS18770.1 - 0.2 11.5 6.8 9.7 6.1 0.0 4.7 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 KOS18770.1 - 1.5 8.9 18.9 7 6.7 0.1 6.1 6 1 1 7 7 5 0 Tetratricopeptide repeat Histone PF00125.19 KOS18771.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KOS18771.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KOS18771.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KOS18771.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KOS18771.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KOS18771.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RRM_1 PF00076.17 KOS18772.1 - 8.2e-13 47.7 0.0 2.3e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS18772.1 - 5.3e-10 38.9 0.0 8.6e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS18772.1 - 1e-09 38.2 0.0 1.9e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup88 PF10168.4 KOS18773.1 - 8.5e-08 30.5 5.4 0.012 13.5 2.7 3.1 2 1 0 2 2 2 2 Nuclear pore component Nup160 PF11715.3 KOS18773.1 - 0.013 13.7 0.4 0.019 13.1 0.3 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Gp-FAR-1 PF05823.7 KOS18773.1 - 0.18 11.7 0.3 0.42 10.5 0.2 1.8 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) WD40 PF00400.27 KOS18773.1 - 0.21 11.5 2.0 1.2 9.1 0.6 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat Sedlin_N PF04628.8 KOS18774.1 - 2.9e-40 137.1 0.0 3.2e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KOS18774.1 - 0.00014 21.5 0.0 0.0039 16.8 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family L31 PF09784.4 KOS18775.1 - 1.1e-45 153.8 1.7 1.2e-45 153.7 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 PrpF PF04303.8 KOS18776.1 - 5.6e-76 255.6 0.0 6.4e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 PrpF protein AdoHcyase PF05221.12 KOS18777.1 - 3.2e-135 449.2 0.2 3.7e-135 449.0 0.2 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KOS18777.1 - 2e-83 278.1 2.4 3.3e-83 277.4 1.7 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KOS18777.1 - 3.2e-06 26.4 0.1 6.4e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 KOS18777.1 - 0.0072 15.9 0.1 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 KOS18777.1 - 0.031 13.6 0.7 0.06 12.7 0.5 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TMEM107 PF14995.1 KOS18777.1 - 0.035 14.2 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein TrkA_N PF02254.13 KOS18777.1 - 0.058 13.3 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain EBP PF05241.7 KOS18778.1 - 1.2e-38 132.0 6.0 1.4e-38 131.8 4.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein Metallophos PF00149.23 KOS18779.1 - 2.5e-10 40.0 3.1 3.7e-10 39.5 2.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Lipase_GDSL_3 PF14606.1 KOS18779.1 - 0.065 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Fungal_trans PF04082.13 KOS18780.1 - 1.2e-10 40.7 0.4 1.7e-10 40.2 0.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pex16 PF08610.5 KOS18781.1 - 1.8e-102 342.8 0.1 7e-102 340.8 0.1 1.7 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) 7TMR-DISMED2 PF07696.6 KOS18781.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 7TMR-DISM extracellular 2 SRR1 PF07985.7 KOS18782.1 - 2.2e-06 27.4 0.0 4.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 SRR1 Glyco_hydro_17 PF00332.13 KOS18783.1 - 2e-08 33.6 0.6 1.6e-06 27.3 0.2 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF3169 PF11368.3 KOS18783.1 - 0.23 10.6 1.1 0.36 10.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF2897 PF11446.3 KOS18783.1 - 4.9 7.0 5.4 11 5.9 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) zf-C2H2_4 PF13894.1 KOS18784.1 - 0.0061 16.8 21.1 0.055 13.8 1.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KOS18784.1 - 0.014 15.6 1.1 0.014 15.6 0.7 3.7 3 1 1 4 4 4 0 Zinc finger, C2H2 type ZZ PF00569.12 KOS18784.1 - 0.033 13.7 3.5 0.033 13.7 2.4 2.3 2 0 0 2 2 2 0 Zinc finger, ZZ type TNFR_c6 PF00020.13 KOS18784.1 - 0.26 11.3 6.8 0.23 11.5 2.0 2.5 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region A2L_zn_ribbon PF08792.5 KOS18784.1 - 0.9 9.0 7.7 3.9 7.0 0.1 2.9 2 1 0 2 2 2 0 A2L zinc ribbon domain zf-met PF12874.2 KOS18784.1 - 6.5 7.1 16.0 0.22 11.7 0.5 3.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type WD40 PF00400.27 KOS18785.1 - 2e-15 55.9 14.3 0.0068 16.2 0.0 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat PAT1 PF09770.4 KOS18785.1 - 1.6 6.8 11.0 2 6.5 7.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fungal_trans PF04082.13 KOS18786.1 - 2.9e-08 32.9 1.4 5.7e-08 31.9 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FUSC-like PF12805.2 KOS18786.1 - 0.12 11.3 0.6 0.33 9.8 0.4 1.7 1 1 1 2 2 2 0 FUSC-like inner membrane protein yccS O-antigen_lig PF13425.1 KOS18786.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4231 PF14015.1 KOS18787.1 - 0.078 12.9 0.2 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Claudin_2 PF13903.1 KOS18787.1 - 0.11 12.1 0.4 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2892 PF11127.3 KOS18787.1 - 0.77 9.6 4.6 1.8 8.4 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) Glyco_hydro_28 PF00295.12 KOS18788.1 - 4.9e-32 111.1 2.1 8.3e-32 110.4 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KOS18788.1 - 0.27 10.9 9.8 0.42 10.3 5.2 2.1 1 1 1 2 2 2 0 Right handed beta helix region p450 PF00067.17 KOS18789.1 - 6.2e-57 193.1 0.0 7.6e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SKIP_SNW PF02731.10 KOS18790.1 - 5.6e-64 214.3 7.0 5.6e-64 214.3 4.9 2.9 3 0 0 3 3 3 1 SKIP/SNW domain COMPASS-Shg1 PF05205.7 KOS18791.1 - 7e-24 84.1 2.2 1.2e-23 83.4 0.1 2.4 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF1777 PF08648.7 KOS18791.1 - 0.0004 20.1 71.9 0.0004 20.1 49.9 5.1 2 2 3 5 5 5 2 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 KOS18791.1 - 3.4 6.0 134.5 0.0029 16.1 54.6 2.3 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 Med6 PF04934.9 KOS18792.1 - 6.6e-41 139.1 0.0 8.8e-41 138.7 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component HA2 PF04408.18 KOS18793.1 - 7.4e-18 64.4 0.0 2.7e-17 62.6 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KOS18793.1 - 2.4e-13 49.7 0.0 6.5e-13 48.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS18793.1 - 1.1e-08 34.7 0.1 9.6e-08 31.7 0.1 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 KOS18793.1 - 4.5e-08 32.9 0.0 1.1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KOS18793.1 - 3.6e-05 23.9 0.0 0.0001 22.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KOS18793.1 - 0.003 17.0 1.1 0.48 9.8 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 KOS18793.1 - 0.0031 16.4 0.0 0.0065 15.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 KOS18793.1 - 0.02 14.1 0.0 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 KOS18793.1 - 0.034 13.2 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 KOS18793.1 - 0.19 12.0 0.0 0.19 12.0 0.0 3.4 4 0 0 4 4 4 0 AAA domain PhoD PF09423.5 KOS18794.1 - 2.1e-56 191.4 0.0 2.6e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Rrp15p PF07890.7 KOS18795.1 - 3.2e-35 121.0 7.2 3.2e-35 121.0 5.0 3.2 2 1 0 2 2 2 1 Rrp15p Nop14 PF04147.7 KOS18795.1 - 2.3 6.0 37.0 3.4 5.4 25.6 1.3 1 0 0 1 1 1 0 Nop14-like family Fer2 PF00111.22 KOS18796.1 - 2.3e-13 49.6 0.7 2.7e-13 49.4 0.5 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain AKAP7_NLS PF10469.4 KOS18797.1 - 1.9e-27 96.3 0.0 3.7e-27 95.3 0.0 1.4 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain V_ATPase_I PF01496.14 KOS18798.1 - 0.14 9.9 0.6 0.24 9.2 0.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HEAT_EZ PF13513.1 KOS18798.1 - 0.43 11.1 3.6 0.28 11.7 0.5 2.3 2 0 0 2 2 2 0 HEAT-like repeat DUF2196 PF09962.4 KOS18800.1 - 9.1e-22 76.6 0.1 1.2e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Sugar_tr PF00083.19 KOS18801.1 - 8.1e-100 334.5 19.5 9.4e-100 334.3 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS18801.1 - 4.9e-17 61.6 36.6 4.9e-17 61.6 25.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KOS18802.1 - 7.8e-55 185.8 0.0 1e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS18802.1 - 6.9e-25 87.5 0.0 1e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS18802.1 - 2e-05 23.6 0.0 2.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS18802.1 - 0.0062 16.3 0.8 0.49 10.0 0.0 3.0 3 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KOS18802.1 - 0.038 13.0 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-Apc11 PF12861.2 KOS18803.1 - 1.7e-31 107.8 3.1 1.9e-31 107.7 2.2 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KOS18803.1 - 1.3e-24 86.0 2.4 1.5e-24 85.8 1.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-HIT PF04438.11 KOS18803.1 - 0.02 14.5 1.0 0.038 13.6 0.7 1.5 1 0 0 1 1 1 0 HIT zinc finger ARF7EP_C PF14949.1 KOS18803.1 - 0.11 12.8 2.6 0.13 12.7 1.8 1.1 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Opy2 PF09463.5 KOS18803.1 - 0.47 10.5 3.9 0.72 9.9 2.7 1.3 1 0 0 1 1 1 0 Opy2 protein zf-RING_2 PF13639.1 KOS18803.1 - 1.5 8.7 11.1 12 5.8 7.7 2.4 1 1 0 1 1 1 0 Ring finger domain Ribosomal_L31e PF01198.14 KOS18804.1 - 6.9e-35 118.5 2.8 8.8e-35 118.2 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e UQ_con PF00179.21 KOS18805.1 - 1e-41 141.6 0.0 1.6e-39 134.5 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS18805.1 - 0.0003 20.5 0.0 0.00046 19.9 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KOS18805.1 - 0.00084 19.2 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KOS18805.1 - 0.0041 16.7 0.0 0.0072 16.0 0.0 1.4 1 1 0 1 1 1 1 UEV domain Rhodanese PF00581.15 KOS18806.1 - 2e-21 76.4 0.0 1e-11 45.1 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Ribosomal_S5 PF00333.15 KOS18807.1 - 2.2e-28 97.7 2.1 2.2e-28 97.7 1.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KOS18807.1 - 2e-21 75.0 0.0 3.7e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Nucleoplasmin PF03066.10 KOS18808.1 - 0.01 15.3 6.6 0.011 15.2 4.6 1.0 1 0 0 1 1 1 0 Nucleoplasmin Senescence_reg PF04520.8 KOS18808.1 - 0.066 13.7 1.5 0.07 13.6 1.1 1.0 1 0 0 1 1 1 0 Senescence regulator RXT2_N PF08595.6 KOS18808.1 - 0.077 12.7 3.1 0.088 12.6 2.2 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4140 PF13600.1 KOS18808.1 - 0.096 13.1 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3073 PF11273.3 KOS18808.1 - 0.13 12.8 2.7 0.14 12.6 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) PBP1_TM PF14812.1 KOS18808.1 - 0.17 12.2 5.5 0.2 11.9 3.8 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 KOS18808.1 - 0.22 10.6 3.5 0.25 10.4 2.4 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Sporozoite_P67 PF05642.6 KOS18808.1 - 0.26 9.1 3.5 0.24 9.2 2.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.8 KOS18808.1 - 0.3 10.6 4.8 0.28 10.7 3.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.7 KOS18808.1 - 0.63 9.1 5.4 0.68 9.0 3.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 KOS18808.1 - 0.79 8.1 5.3 0.8 8.1 3.7 1.0 1 0 0 1 1 1 0 Daxx Family LAT PF15234.1 KOS18808.1 - 0.82 9.0 2.9 0.85 9.0 2.0 1.0 1 0 0 1 1 1 0 Linker for activation of T-cells DUF2457 PF10446.4 KOS18808.1 - 1.8 7.1 12.0 2.1 6.9 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 KOS18808.1 - 4.3 6.5 6.6 4 6.6 4.6 1.0 1 0 0 1 1 1 0 NOA36 protein S-antigen PF05756.6 KOS18808.1 - 4.6 7.3 7.5 4.8 7.2 5.2 1.1 1 0 0 1 1 1 0 S-antigen protein DUF4366 PF14283.1 KOS18808.1 - 5.4 6.3 7.5 6.3 6.1 5.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CENP-B_dimeris PF09026.5 KOS18808.1 - 8 6.7 14.1 10 6.4 9.8 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HAMP PF00672.20 KOS18809.1 - 2.8e-49 165.1 19.3 1.4e-10 41.1 0.3 7.2 6 0 0 6 6 6 6 HAMP domain Response_reg PF00072.19 KOS18809.1 - 4.3e-30 104.0 0.3 5.5e-26 90.7 0.1 2.9 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.21 KOS18809.1 - 2.9e-28 97.8 0.1 1.3e-27 95.7 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KOS18809.1 - 1.9e-19 69.4 5.9 2.3e-18 65.9 0.4 4.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF883 PF05957.8 KOS18809.1 - 0.00071 19.9 11.2 1.2 9.5 0.2 6.0 3 2 2 5 5 5 2 Bacterial protein of unknown function (DUF883) DUF2365 PF10157.4 KOS18809.1 - 0.096 12.5 16.1 7.7 6.3 0.1 7.2 5 2 2 7 7 7 0 Uncharacterized conserved protein (DUF2365) MxiH PF09392.5 KOS18809.1 - 0.39 11.3 9.9 14 6.3 0.0 5.7 3 1 1 4 4 4 0 Type III secretion needle MxiH like NAAA-beta PF15508.1 KOS18809.1 - 1.1 9.6 8.4 4 7.8 0.1 5.5 6 2 2 8 8 8 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Pox_A_type_inc PF04508.7 KOS18809.1 - 2 8.4 11.4 8.6 6.4 0.1 5.8 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat VBS PF08913.5 KOS18809.1 - 7.1 6.8 13.6 0.84 9.8 0.2 4.8 2 2 1 4 4 4 0 Vinculin Binding Site Siah-Interact_N PF09032.6 KOS18810.1 - 0.06 13.4 0.5 0.074 13.1 0.4 1.2 1 0 0 1 1 1 0 Siah interacting protein, N terminal Cnd2 PF05786.9 KOS18812.1 - 3.9e-209 696.7 8.0 5.2e-209 696.3 5.5 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 Na_Ca_ex PF01699.19 KOS18813.1 - 4e-47 159.3 23.5 2.7e-26 91.8 2.0 3.6 3 1 1 4 4 4 2 Sodium/calcium exchanger protein MARVEL PF01284.18 KOS18813.1 - 0.0024 17.6 1.2 0.0024 17.6 0.8 4.3 4 1 1 5 5 5 2 Membrane-associating domain PMM PF03332.8 KOS18814.1 - 2.3e-103 344.5 0.0 2.8e-103 344.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KOS18814.1 - 0.015 14.9 0.0 0.18 11.3 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase WW PF00397.21 KOS18815.1 - 7.3e-10 38.5 0.1 3e-09 36.5 0.1 2.2 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 KOS18815.1 - 0.00013 20.6 1.9 0.00062 18.4 0.4 2.0 2 0 0 2 2 2 1 PhoD-like phosphatase MutS_V PF00488.16 KOS18816.1 - 1.3e-83 279.9 0.0 2.4e-83 279.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KOS18816.1 - 4.5e-40 137.6 1.8 8e-40 136.8 1.3 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KOS18816.1 - 2.7e-28 98.2 0.0 5.8e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KOS18816.1 - 1.9e-09 37.7 0.0 8e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KOS18816.1 - 5.8e-06 26.3 0.0 1.5e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV Sigma70_ner PF04546.8 KOS18816.1 - 0.21 11.2 5.7 2.3 7.8 1.7 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region PRTP PF01366.13 KOS18816.1 - 0.24 9.3 0.0 0.39 8.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Herpes_LMP1 PF05297.6 KOS18816.1 - 6.9 5.4 6.6 12 4.7 4.6 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Prenyltrans PF00432.16 KOS18817.1 - 1.6e-59 197.0 17.8 1.9e-11 43.3 0.3 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KOS18817.1 - 8.1e-43 145.4 0.0 6.4e-17 61.9 0.0 3.6 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KOS18817.1 - 2.1e-12 47.0 0.0 0.00071 19.5 0.0 3.6 2 1 1 3 3 3 3 Prenyltransferase-like CDP-OH_P_transf PF01066.16 KOS18817.1 - 0.034 14.4 0.3 11 6.3 0.1 2.9 3 0 0 3 3 3 0 CDP-alcohol phosphatidyltransferase BAH PF01426.13 KOS18818.1 - 1.5e-16 60.2 0.0 3.2e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.1 KOS18818.1 - 3.7e-07 30.1 0.7 2e-06 27.7 0.0 2.5 3 0 0 3 3 3 1 PHD-zinc-finger like domain Myb_DNA-binding PF00249.26 KOS18818.1 - 0.0067 16.4 0.0 0.025 14.6 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-HC5HC2H PF13771.1 KOS18818.1 - 0.022 14.9 0.7 0.57 10.3 0.0 3.1 3 0 0 3 3 3 0 PHD-like zinc-binding domain GATA PF00320.22 KOS18818.1 - 5.3 6.4 13.1 0.064 12.6 2.1 2.7 3 0 0 3 3 3 0 GATA zinc finger Pkinase PF00069.20 KOS18819.1 - 4.5e-35 121.0 0.0 1.1e-18 67.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KOS18819.1 - 3.5e-13 49.2 0.0 1.1e-10 41.0 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KOS18819.1 - 5.7e-06 26.2 0.0 1.2e-05 25.2 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KOS18819.1 - 0.0018 17.3 0.0 0.18 10.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Cupin_8 PF13621.1 KOS18820.1 - 9.4e-20 71.1 0.0 6.9e-19 68.3 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KOS18820.1 - 1e-10 41.8 0.1 4.7e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 KOS18820.1 - 6.4e-09 35.3 0.1 6.4e-09 35.3 0.0 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KOS18820.1 - 1.8e-07 30.5 0.1 5.4e-07 29.1 0.1 1.8 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 KOS18820.1 - 0.0016 18.7 0.0 0.003 17.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Cupin_4 PF08007.7 KOS18820.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein FAM212 PF15342.1 KOS18820.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 FAM212 family TT_ORF2 PF02957.10 KOS18820.1 - 0.37 11.4 1.5 0.71 10.5 1.1 1.4 1 0 0 1 1 1 0 TT viral ORF2 DUF1771 PF08590.5 KOS18821.1 - 4.5e-14 52.2 11.5 3.4e-13 49.4 7.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 KOS18821.1 - 5.8e-10 39.2 0.0 1.8e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 KOS18821.1 - 2.9e-06 26.8 4.5 0.0059 16.2 0.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 KOS18821.1 - 0.018 15.1 0.0 0.049 13.7 0.0 1.8 1 0 0 1 1 1 0 HBS1 N-terminus MARVEL PF01284.18 KOS18822.1 - 0.0046 16.7 14.6 0.019 14.8 10.3 1.8 1 1 0 1 1 1 1 Membrane-associating domain DUF3329 PF11808.3 KOS18822.1 - 0.055 13.5 2.5 0.41 10.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3329) Ninjurin PF04923.7 KOS18822.1 - 0.13 12.0 3.1 0.5 10.1 1.0 2.3 1 1 1 2 2 2 0 Ninjurin DEAD PF00270.24 KOS18823.1 - 2.6e-43 147.4 2.3 3.3e-43 147.0 1.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS18823.1 - 1.3e-27 95.4 0.2 6.2e-27 93.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS18823.1 - 0.0011 18.8 0.1 0.0021 17.8 0.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KOS18823.1 - 0.0092 15.5 0.3 0.027 14.0 0.1 1.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KOS18823.1 - 0.016 14.9 0.1 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 KOS18823.1 - 0.045 13.5 0.0 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 KOS18823.1 - 0.05 13.7 0.1 0.18 11.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 KOS18823.1 - 0.065 12.5 0.3 0.19 10.9 0.2 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain tRNA-synt_1b PF00579.20 KOS18823.1 - 0.089 11.8 0.1 0.3 10.1 0.0 1.9 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) Fanconi_A PF03511.9 KOS18823.1 - 0.099 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein Helicase_RecD PF05127.9 KOS18823.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Helicase Abhydrolase_6 PF12697.2 KOS18824.1 - 1.8e-12 47.6 10.6 5.1e-11 42.8 3.1 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS18824.1 - 1.1e-09 38.1 0.3 1.5e-08 34.5 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS18824.1 - 1.3e-06 28.1 0.6 2.6e-05 24.0 0.2 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KOS18824.1 - 0.041 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S28 PF05577.7 KOS18824.1 - 0.097 11.2 0.0 0.32 9.5 0.0 1.7 1 1 0 1 1 1 0 Serine carboxypeptidase S28 DEAD PF00270.24 KOS18825.1 - 1.2e-09 37.9 0.6 5.2e-06 26.0 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase HHH_5 PF14520.1 KOS18825.1 - 4e-06 26.9 0.0 3.5e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain HTH_psq PF05225.11 KOS18825.1 - 0.1 12.1 0.0 0.4 10.2 0.0 2.0 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Gas_vesicle_C PF01304.12 KOS18825.1 - 3.7 7.2 5.7 6.2 6.5 1.5 2.9 3 0 0 3 3 3 0 Gas vesicles protein GVPc repeated domain SNARE_assoc PF09335.6 KOS18826.1 - 1.4e-13 51.0 4.5 1.4e-13 51.0 3.1 2.6 3 0 0 3 3 3 1 SNARE associated Golgi protein Neurochondrin PF05536.6 KOS18828.1 - 6.6e-90 301.9 0.7 1.9e-89 300.4 0.5 1.6 1 1 0 1 1 1 1 Neurochondrin RIX1 PF08167.7 KOS18828.1 - 3.6e-07 29.9 2.3 1e-06 28.4 0.2 2.6 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Rhabdo_ncap PF00945.13 KOS18829.1 - 0.057 11.9 2.1 0.1 11.1 1.3 1.5 1 1 1 2 2 2 0 Rhabdovirus nucleocapsid protein Daxx PF03344.10 KOS18829.1 - 0.96 7.8 7.6 0.58 8.5 3.6 1.7 2 0 0 2 2 2 0 Daxx Family Ras PF00071.17 KOS18830.1 - 2.5e-34 118.0 0.0 3.2e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS18830.1 - 4.8e-07 30.2 0.0 7.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein RRM_6 PF14259.1 KOS18831.1 - 8.2e-41 137.8 0.0 5.1e-11 42.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS18831.1 - 2.2e-39 132.9 0.1 2e-12 46.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS18831.1 - 9.1e-22 76.6 0.1 9.7e-06 25.3 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 KOS18831.1 - 6.6e-13 48.0 4.5 3.3e-12 45.7 3.1 2.3 1 0 0 1 1 1 1 Putative RRM domain RRM_3 PF08777.6 KOS18831.1 - 0.0003 20.6 0.1 0.03 14.1 0.1 2.6 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 KOS18831.1 - 0.0035 17.0 0.1 3 7.6 0.0 3.4 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 KOS18831.1 - 0.014 15.3 0.0 0.29 11.1 0.0 2.9 3 1 0 3 3 3 0 RNA binding domain His_Phos_2 PF00328.17 KOS18832.1 - 4.2e-20 72.3 0.0 1e-17 64.5 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Abhydrolase_6 PF12697.2 KOS18834.1 - 1e-06 28.7 2.9 4e-06 26.8 2.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KOS18834.1 - 0.013 14.7 0.0 0.03 13.5 0.0 1.5 2 0 0 2 2 2 0 Putative serine esterase (DUF676) LCAT PF02450.10 KOS18834.1 - 0.034 13.1 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DNA_ligase_A_M PF01068.16 KOS18836.1 - 1.7e-59 200.5 0.3 2.1e-47 161.1 0.1 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KOS18836.1 - 2.1e-48 164.5 0.0 4.1e-48 163.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KOS18836.1 - 8.7e-29 99.7 1.0 5.5e-28 97.2 0.0 2.9 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region Dicty_REP PF05086.7 KOS18836.1 - 0.19 9.4 11.6 0.27 8.9 8.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.5 KOS18836.1 - 4 5.7 4.4 6.3 5.0 3.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Voltage_CLC PF00654.15 KOS18837.1 - 5.7e-91 305.1 25.2 9.4e-91 304.4 17.5 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel DUF2052 PF09747.4 KOS18838.1 - 7.3e-27 94.4 0.3 9e-27 94.1 0.2 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Piwi PF02171.12 KOS18839.1 - 4.6e-65 219.5 0.0 6.7e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KOS18839.1 - 1.6e-12 46.6 0.1 3e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KOS18839.1 - 2.9e-11 42.8 0.0 7e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 PAZ domain GFO_IDH_MocA PF01408.17 KOS18840.1 - 7.1e-22 78.1 0.1 1.7e-21 76.9 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 KOS18840.1 - 0.00093 19.4 0.0 0.0037 17.5 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.12 KOS18840.1 - 0.051 13.3 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Fungal_trans PF04082.13 KOS18841.1 - 1.1e-24 86.7 0.1 1.9e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 KOS18841.1 - 0.014 15.3 0.1 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain zf-C4pol PF14260.1 KOS18841.1 - 0.18 11.7 2.4 3.3 7.7 0.2 2.4 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Sugar_tr PF00083.19 KOS18842.1 - 4.6e-84 282.5 18.3 5.5e-84 282.3 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS18842.1 - 6.3e-31 107.3 29.3 1.1e-28 100.0 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KOS18842.1 - 2.7e-05 22.7 1.0 2.7e-05 22.7 0.7 3.3 2 2 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KOS18842.1 - 0.0017 16.6 3.1 0.0017 16.6 2.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 KOS18843.1 - 3.7e-27 95.2 4.8 6.8e-27 94.4 3.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS18843.1 - 5.1e-19 69.0 0.0 1e-18 67.9 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS18843.1 - 6.6e-14 51.9 1.0 1.2e-13 51.1 0.7 1.4 1 0 0 1 1 1 1 KR domain AAA_19 PF13245.1 KOS18843.1 - 0.00017 21.2 3.2 0.00034 20.3 0.1 3.0 3 0 0 3 3 3 1 Part of AAA domain Zeta_toxin PF06414.7 KOS18843.1 - 0.0011 18.0 0.4 0.0074 15.4 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 KOS18843.1 - 0.0014 17.7 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KOS18843.1 - 0.0017 19.1 0.0 0.0093 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KOS18843.1 - 0.0023 18.1 0.1 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Saccharop_dh PF03435.13 KOS18843.1 - 0.0026 16.8 0.2 0.0039 16.2 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase AAA_33 PF13671.1 KOS18843.1 - 0.0035 17.2 0.2 0.027 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KOS18843.1 - 0.0069 16.7 0.0 0.054 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KOS18843.1 - 0.0097 15.9 0.2 0.037 14.0 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain PRK PF00485.13 KOS18843.1 - 0.012 15.1 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.10 KOS18843.1 - 0.013 15.1 0.0 0.058 13.1 0.0 1.9 2 0 0 2 2 2 0 NTPase Epimerase PF01370.16 KOS18843.1 - 0.016 14.6 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AAA_22 PF13401.1 KOS18843.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KOS18843.1 - 0.043 13.4 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 KOS18843.1 - 0.05 12.4 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NAD_binding_10 PF13460.1 KOS18843.1 - 0.053 13.5 1.4 0.26 11.2 0.5 2.3 2 1 0 2 2 2 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 KOS18843.1 - 0.057 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AAA_5 PF07728.9 KOS18843.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KOS18843.1 - 0.079 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 KOS18843.1 - 0.083 12.4 0.2 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KOS18843.1 - 0.15 11.0 0.1 0.46 9.4 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus ADH_N PF08240.7 KOS18844.1 - 3.2e-32 110.5 0.9 3.2e-32 110.5 0.6 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KOS18844.1 - 9.3e-20 70.4 2.9 9.3e-20 70.4 2.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KOS18844.1 - 1.9e-06 28.7 0.2 4.6e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KOS18844.1 - 0.00088 19.8 0.4 0.0017 18.9 0.3 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KOS18844.1 - 0.0097 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KOS18844.1 - 0.031 14.3 0.3 0.057 13.4 0.2 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KOS18844.1 - 0.036 14.5 0.1 0.071 13.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 KOS18845.1 - 4.6e-30 104.7 9.2 5.8e-30 104.4 6.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS18845.1 - 3.3e-26 92.5 0.0 3.9e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS18845.1 - 6e-14 52.1 4.8 1.4e-13 50.9 3.3 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KOS18845.1 - 0.0014 18.1 0.2 0.0069 15.8 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KOS18845.1 - 0.11 11.3 1.0 1.7 7.4 0.0 2.3 2 1 0 2 2 2 0 RmlD substrate binding domain CMD PF02627.15 KOS18845.1 - 1.5 8.6 6.6 3 7.7 1.1 2.8 1 1 1 2 2 2 0 Carboxymuconolactone decarboxylase family Response_reg PF00072.19 KOS18846.1 - 1.5e-21 76.5 0.0 1.6e-14 53.8 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain zf-trcl PF13451.1 KOS18847.1 - 0.97 9.1 5.6 3 7.5 0.3 2.5 3 0 0 3 3 3 0 Probable zinc-binding domain MFS_1 PF07690.11 KOS18848.1 - 1.4e-28 99.6 47.3 1.1e-25 90.1 21.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS18848.1 - 0.00092 17.8 13.5 0.00092 17.8 9.3 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter ATG22 PF11700.3 KOS18848.1 - 0.091 11.2 22.0 0.091 11.2 2.3 2.3 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like DUF4611 PF15387.1 KOS18848.1 - 1.5 9.0 4.4 3 8.0 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CFEM PF05730.6 KOS18849.1 - 1.1e-13 50.8 5.8 1.2e-13 50.6 4.0 1.1 1 0 0 1 1 1 1 CFEM domain OAF PF14941.1 KOS18849.1 - 0.061 12.4 0.7 0.056 12.5 0.5 1.1 1 0 0 1 1 1 0 Transcriptional regulator, Out at first CAF1A PF12253.3 KOS18850.1 - 2.6e-18 65.9 4.7 2.6e-18 65.9 3.3 2.1 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 KOS18850.1 - 0.00062 19.2 33.6 0.0015 17.9 23.1 1.8 1 1 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal ATP11 PF06644.6 KOS18850.1 - 2.4 7.5 12.5 4.5 6.7 8.7 1.5 1 0 0 1 1 1 0 ATP11 protein OPT PF03169.10 KOS18852.1 - 4.1e-122 408.6 43.3 4.8e-122 408.4 30.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2207 PF09972.4 KOS18852.1 - 0.11 11.0 0.1 0.64 8.5 0.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) 2-Hacid_dh_C PF02826.14 KOS18855.1 - 3.9e-52 175.9 0.0 8.2e-52 174.9 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KOS18855.1 - 1.9e-16 59.7 0.0 2.9e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KOS18855.1 - 5.7e-05 23.0 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KOS18855.1 - 0.028 13.7 0.1 0.088 12.1 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain EXS PF03124.9 KOS18856.1 - 3e-90 302.7 28.5 3.8e-90 302.3 19.8 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KOS18856.1 - 6e-53 180.3 0.0 2.5e-52 178.3 0.0 2.1 2 1 0 2 2 2 1 SPX domain Peptidase_M18 PF02127.10 KOS18857.1 - 4.7e-112 374.6 0.0 5.9e-112 374.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Histone PF00125.19 KOS18858.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KOS18858.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KOS18858.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KOS18858.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KOS18858.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KOS18858.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T zf-C2H2 PF00096.21 KOS18859.1 - 6.5e-06 26.1 6.5 0.076 13.3 2.4 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS18859.1 - 2.5e-05 24.3 9.1 0.0061 16.8 2.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Saccharop_dh PF03435.13 KOS18860.1 - 3e-103 345.8 0.0 3.4e-103 345.6 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KOS18860.1 - 5.9e-05 23.1 0.1 9.3e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KOS18860.1 - 0.00022 21.3 0.1 0.00033 20.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 KOS18860.1 - 0.003 18.0 0.1 0.0053 17.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 KOS18860.1 - 0.014 15.4 1.0 0.084 12.8 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_3 PF03447.11 KOS18860.1 - 0.022 15.1 0.0 0.093 13.1 0.1 1.9 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain IlvN PF07991.7 KOS18860.1 - 0.028 13.8 0.0 0.089 12.1 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain vATP-synt_AC39 PF01992.11 KOS18860.1 - 0.03 13.4 0.0 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 ATP synthase (C/AC39) subunit UDPG_MGDP_dh_N PF03721.9 KOS18860.1 - 0.056 12.8 0.3 0.12 11.7 0.2 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 KOS18860.1 - 0.057 13.8 0.2 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF2325 PF10087.4 KOS18860.1 - 0.15 11.9 0.3 0.35 10.7 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Histone PF00125.19 KOS18861.1 - 3.7e-31 107.0 0.4 5.8e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KOS18861.1 - 4.1e-06 26.8 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KOS18861.1 - 0.0041 17.1 0.0 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KOS18861.1 - 0.013 15.1 0.1 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated DDHD PF02862.12 KOS18862.1 - 1.8e-37 129.3 0.0 1e-34 120.2 0.0 2.2 1 1 0 1 1 1 1 DDHD domain Abhydrolase_6 PF12697.2 KOS18862.1 - 0.00062 19.7 0.1 0.0022 17.8 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS18862.1 - 0.0051 16.5 0.0 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KOS18862.1 - 0.012 14.9 0.0 0.034 13.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) APG6 PF04111.7 KOS18863.1 - 7.5e-123 409.5 0.0 1.2e-122 408.9 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF4472 PF14739.1 KOS18863.1 - 0.023 15.1 1.9 0.023 15.1 1.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) TMF_TATA_bd PF12325.3 KOS18863.1 - 0.14 11.9 7.3 0.12 12.1 1.7 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 KOS18863.1 - 0.4 10.5 9.1 0.086 12.7 3.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 KOS18863.1 - 0.67 10.3 3.6 0.24 11.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 KOS18863.1 - 1.1 7.0 2.8 1.5 6.5 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIA PF03153.8 KOS18863.1 - 1.3 8.8 7.7 1.9 8.3 5.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 KOS18864.1 - 2.4e-17 62.0 19.3 0.00018 21.2 0.0 7.1 8 1 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 KOS18864.1 - 0.018 14.7 0.1 0.25 11.0 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 KOS18864.1 - 0.28 10.8 4.7 0.094 12.3 0.7 2.2 2 0 0 2 2 2 0 HIRA B motif AbiH PF14253.1 KOS18865.1 - 2 7.9 6.2 0.33 10.4 0.7 1.9 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH Pkinase PF00069.20 KOS18866.1 - 6e-60 202.5 0.0 6.9e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS18866.1 - 1.1e-19 70.5 0.0 1.6e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS18866.1 - 1.5e-09 37.9 0.0 5.3e-06 26.3 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KOS18866.1 - 0.0089 15.6 0.1 0.02 14.4 0.1 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KOS18866.1 - 0.022 13.7 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KOS18866.1 - 0.063 12.3 0.1 0.15 11.1 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Scm3 PF10384.4 KOS18868.1 - 9.9e-21 72.9 0.1 9.9e-21 72.9 0.1 2.3 2 0 0 2 2 1 1 Centromere protein Scm3 CDC45 PF02724.9 KOS18868.1 - 4.4e-07 28.3 0.4 4.6e-07 28.2 0.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Hid1 PF12722.2 KOS18868.1 - 0.00054 17.7 8.7 0.00067 17.4 6.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein tRNA-synt_1e PF01406.14 KOS18868.1 - 0.0063 15.6 1.6 0.0093 15.1 1.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain CENP-T PF15511.1 KOS18868.1 - 0.02 14.1 13.2 0.027 13.7 9.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T ACR_tran PF00873.14 KOS18868.1 - 0.19 9.1 1.3 0.25 8.6 0.9 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF2457 PF10446.4 KOS18868.1 - 0.26 9.9 19.1 0.36 9.5 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.6 KOS18868.1 - 1.3 8.5 14.9 1.9 7.9 10.3 1.2 1 0 0 1 1 1 0 PPP4R2 Med15 PF09606.5 KOS18868.1 - 2.2 6.3 25.4 3 5.9 17.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TSA PF03249.8 KOS18868.1 - 2.2 6.7 10.5 3.1 6.2 7.3 1.2 1 0 0 1 1 1 0 Type specific antigen BTV_NS2 PF04514.7 KOS18868.1 - 3.3 6.4 12.1 4.5 6.0 8.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Sporozoite_P67 PF05642.6 KOS18868.1 - 3.9 5.2 7.4 5.3 4.7 5.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.7 KOS18868.1 - 6.5 5.9 20.2 9.6 5.3 14.0 1.2 1 0 0 1 1 1 0 SDA1 SMN PF06003.7 KOS18868.1 - 6.9 5.6 10.5 2.6 7.0 5.4 1.7 1 1 1 2 2 2 0 Survival motor neuron protein (SMN) Astro_capsid PF03115.9 KOS18868.1 - 8.2 4.5 10.7 11 4.1 7.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor FlaC_arch PF05377.6 KOS18871.1 - 0.0059 16.4 0.3 0.011 15.6 0.2 1.5 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) Leu_zip PF15294.1 KOS18871.1 - 0.01 14.9 0.1 0.013 14.6 0.1 1.1 1 0 0 1 1 1 0 Leucine zipper ABG_transport PF03806.8 KOS18871.1 - 0.037 12.0 0.0 0.04 11.9 0.0 1.0 1 0 0 1 1 1 0 AbgT putative transporter family bZIP_1 PF00170.16 KOS18871.1 - 0.044 13.7 0.7 0.072 13.0 0.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF4199 PF13858.1 KOS18871.1 - 0.062 13.2 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) MgtE PF01769.11 KOS18871.1 - 0.068 13.4 0.8 0.11 12.7 0.6 1.4 1 1 1 2 2 2 0 Divalent cation transporter Srg PF02118.16 KOS18871.1 - 0.12 11.8 0.6 0.13 11.7 0.4 1.1 1 0 0 1 1 1 0 Srg family chemoreceptor bZIP_2 PF07716.10 KOS18871.1 - 0.13 12.1 0.7 0.22 11.3 0.5 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Sfi1_C PF10638.4 KOS18871.1 - 0.15 12.5 0.9 0.31 11.4 0.3 1.6 2 0 0 2 2 2 0 Spindle body associated protein C-terminus DUF4006 PF13179.1 KOS18871.1 - 0.39 10.3 2.1 2.4 7.7 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF4006) PspB PF06667.7 KOS18871.1 - 1 9.3 3.2 0.5 10.3 0.5 1.7 1 1 1 2 2 2 0 Phage shock protein B Atg14 PF10186.4 KOS18872.1 - 1.5e-72 244.0 0.1 2.8e-72 243.2 0.0 1.4 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DnaJ PF00226.26 KOS18873.1 - 2.1e-12 46.5 0.1 4.7e-12 45.4 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain PepSY_2 PF13670.1 KOS18873.1 - 8.6 6.3 9.5 23 4.9 1.3 3.6 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Ribosomal_L10 PF00466.15 KOS18875.1 - 1.4e-23 82.7 0.0 2.9e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KOS18875.1 - 3.2e-15 56.2 9.2 6.2e-15 55.3 4.8 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF371 PF04027.8 KOS18875.1 - 0.14 11.8 0.0 0.62 9.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF371) WD40 PF00400.27 KOS18876.1 - 0.00061 19.5 0.0 0.099 12.5 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Mucin PF01456.12 KOS18876.1 - 0.044 13.5 23.4 0.12 12.1 16.2 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 KOS18876.1 - 0.17 11.6 8.3 0.39 10.4 5.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glycoprotein_G PF00802.14 KOS18876.1 - 2.3 7.2 11.5 4 6.5 7.9 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Glyco_hydro_38 PF01074.17 KOS18877.1 - 8.7e-91 303.9 0.3 1.3e-90 303.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KOS18877.1 - 9.8e-66 222.4 0.0 1.7e-65 221.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KOS18877.1 - 1e-26 92.9 0.4 4.8e-26 90.7 0.0 2.3 3 0 0 3 3 3 1 Alpha mannosidase, middle domain MutS_V PF00488.16 KOS18878.1 - 1.8e-80 269.7 0.0 2.7e-80 269.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KOS18878.1 - 9e-37 126.8 5.3 1.5e-36 126.1 3.7 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KOS18878.1 - 2.1e-13 50.2 0.0 2.7e-12 46.6 0.0 2.6 3 0 0 3 3 3 1 MutS domain I MutS_II PF05188.12 KOS18878.1 - 7.4e-07 29.2 0.1 2.7e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KOS18878.1 - 1.3e-05 25.3 0.0 3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV CCDC92 PF14916.1 KOS18878.1 - 0.0046 16.5 0.2 0.012 15.1 0.2 1.7 1 0 0 1 1 1 1 Coiled-coil domain of unknown function AAA_29 PF13555.1 KOS18878.1 - 0.034 13.6 0.1 0.089 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KOS18878.1 - 0.25 11.6 2.3 0.58 10.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain HEAT_2 PF13646.1 KOS18879.1 - 0.002 18.3 0.1 0.018 15.3 0.0 2.2 1 1 1 2 2 2 1 HEAT repeats MarR PF01047.17 KOS18879.1 - 0.012 15.3 0.1 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 MarR family Nop14 PF04147.7 KOS18880.1 - 2.3e-243 809.9 59.5 4e-242 805.7 41.2 2.0 1 1 0 1 1 1 1 Nop14-like family DnaJ PF00226.26 KOS18881.1 - 4.1e-25 87.2 2.2 7.5e-25 86.4 1.5 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KOS18881.1 - 3e-23 81.5 0.1 1.9e-18 66.1 0.0 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KOS18881.1 - 2.9e-14 52.8 15.3 6.3e-14 51.7 10.6 1.6 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KOS18881.1 - 0.38 10.4 8.2 0.44 10.2 0.9 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 KOS18881.1 - 1.1 9.1 5.2 13 5.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbons DUF2614 PF11023.3 KOS18881.1 - 1.2 8.9 6.4 6.5 6.5 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) CAP_GLY PF01302.20 KOS18882.1 - 5.3e-16 58.0 1.1 9.8e-16 57.2 0.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain CENP-F_leu_zip PF10473.4 KOS18882.1 - 0.088 12.6 36.8 0.014 15.2 6.7 3.8 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 KOS18882.1 - 0.39 9.3 24.7 0.83 8.2 5.6 3.5 2 1 2 4 4 4 0 Spc7 kinetochore protein AAA_13 PF13166.1 KOS18882.1 - 0.51 8.7 16.3 0.59 8.5 8.6 2.5 2 1 0 2 2 2 0 AAA domain PEARLI-4 PF05278.7 KOS18882.1 - 0.56 9.5 13.1 1.6 8.0 4.7 2.5 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) NPV_P10 PF05531.7 KOS18882.1 - 0.9 9.8 11.1 9.4 6.5 0.2 4.0 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein zf-CCHC_4 PF14392.1 KOS18882.1 - 2 8.1 4.2 6.1 6.6 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle DinB_2 PF12867.2 KOS18882.1 - 4.8 7.5 8.5 17 5.7 4.3 3.0 2 1 0 2 2 2 0 DinB superfamily XPG_I PF00867.13 KOS18883.1 - 3.3e-24 84.7 0.9 6.3e-24 83.8 0.0 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KOS18883.1 - 1.2e-07 31.9 0.0 4.4e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain SDA1 PF05285.7 KOS18883.1 - 0.021 14.1 21.1 0.042 13.1 14.6 1.4 1 0 0 1 1 1 0 SDA1 Ebola_NP PF05505.7 KOS18883.1 - 7.7 4.4 16.8 12 3.8 11.6 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DUF572 PF04502.8 KOS18883.1 - 9.2 5.3 28.8 0.63 9.2 13.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Actin PF00022.14 KOS18884.1 - 1.7e-18 66.2 0.0 4.4e-17 61.6 0.0 2.5 2 1 0 2 2 2 1 Actin MFS_1 PF07690.11 KOS18885.1 - 2.2e-30 105.5 31.1 2.2e-30 105.5 21.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_23 PF13489.1 KOS18886.1 - 1.1e-15 57.7 0.0 1.9e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS18886.1 - 7.1e-08 32.1 0.0 2.6e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS18886.1 - 1.1e-07 32.2 0.0 6.6e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS18886.1 - 1.5e-07 31.8 0.0 1.4e-06 28.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS18886.1 - 1.9e-07 31.6 0.0 2.6e-06 27.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KOS18886.1 - 0.0005 20.1 0.0 0.0046 16.9 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF938 PF06080.7 KOS18886.1 - 0.00087 18.8 0.0 0.0025 17.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF938) MTS PF05175.9 KOS18886.1 - 0.003 16.9 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KOS18886.1 - 0.0035 16.4 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KOS18886.1 - 0.0045 17.3 0.0 0.015 15.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KOS18886.1 - 0.0069 15.4 0.0 0.025 13.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_PK PF05891.7 KOS18886.1 - 0.024 13.9 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.13 KOS18886.1 - 0.03 13.5 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 KOS18886.1 - 0.065 12.2 0.1 0.13 11.3 0.0 1.4 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KOS18886.1 - 0.077 13.0 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 KOS18886.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase F-box PF00646.28 KOS18887.1 - 2.4e-05 23.8 0.2 6.2e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KOS18887.1 - 0.00056 19.5 0.4 0.0013 18.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like Pep3_Vps18 PF05131.9 KOS18888.1 - 2e-38 131.1 0.0 4.1e-38 130.1 0.0 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KOS18888.1 - 3e-09 36.6 6.9 3.7e-07 29.8 0.1 3.2 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 KOS18888.1 - 0.00076 19.2 0.4 0.00076 19.2 0.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KOS18888.1 - 0.0013 18.3 0.6 0.0013 18.3 0.4 1.8 2 0 0 2 2 2 1 zinc-RING finger domain Vps39_2 PF10367.4 KOS18888.1 - 0.0068 16.5 0.1 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 DUF2175 PF09943.4 KOS18888.1 - 0.0094 15.9 0.1 0.045 13.8 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-rbx1 PF12678.2 KOS18888.1 - 0.074 13.1 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KOS18888.1 - 0.13 12.3 0.5 0.36 10.8 0.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rhodanese PF00581.15 KOS18889.1 - 2e-09 37.7 0.0 4.6e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Homeobox PF00046.24 KOS18889.1 - 3.7e-07 29.6 0.0 1.3e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KOS18890.1 - 7.1e-19 67.2 1.3 1.2e-18 66.4 0.9 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KOS18890.1 - 1.9e-09 37.0 2.1 2.7e-09 36.5 1.5 1.2 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KOS18890.1 - 0.026 13.5 0.1 0.83 8.7 0.0 2.2 1 1 1 2 2 2 0 Homeodomain leucine-zipper encoding, Homez MIF PF01187.13 KOS18891.1 - 7.3e-11 42.1 0.0 1.1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) MgsA_C PF12002.3 KOS18892.1 - 3.7e-61 205.6 0.1 2e-60 203.3 0.0 2.0 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KOS18892.1 - 1e-13 51.6 0.0 1.9e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KOS18892.1 - 2.1e-10 40.0 0.0 6.4e-10 38.4 0.0 1.8 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 KOS18892.1 - 1.1e-06 28.2 0.0 6.5e-05 22.4 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KOS18892.1 - 4.9e-06 25.8 0.0 0.065 12.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KOS18892.1 - 1.5e-05 25.0 6.3 0.002 18.1 0.0 3.6 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KOS18892.1 - 2.3e-05 24.5 0.2 0.00032 20.8 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KOS18892.1 - 0.00012 21.8 0.0 0.004 16.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KOS18892.1 - 0.00016 21.5 0.0 0.00038 20.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS18892.1 - 0.00064 19.4 4.9 0.0013 18.4 0.0 3.3 3 0 0 3 3 3 1 Part of AAA domain AAA_3 PF07726.6 KOS18892.1 - 0.0069 15.9 0.0 0.028 13.9 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KOS18892.1 - 0.0088 14.9 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.10 KOS18892.1 - 0.009 15.8 0.1 5.5 6.7 0.0 2.3 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_17 PF13207.1 KOS18892.1 - 0.01 16.6 0.0 0.023 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF927 PF06048.6 KOS18892.1 - 0.011 14.9 0.0 0.011 14.9 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF927) TIP49 PF06068.8 KOS18892.1 - 0.017 13.8 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Sigma54_activ_2 PF14532.1 KOS18892.1 - 0.032 14.2 0.0 0.09 12.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 KOS18892.1 - 0.049 13.9 0.0 0.073 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.1 KOS18892.1 - 0.052 13.2 0.0 5.8 6.5 0.0 2.7 2 1 1 3 3 3 0 DNA polymerase III, delta subunit IstB_IS21 PF01695.12 KOS18892.1 - 0.055 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sgf11 PF08209.6 KOS18892.1 - 0.076 12.3 0.7 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Clathrin-link PF09268.5 KOS18892.1 - 0.084 11.9 2.2 0.17 10.9 1.5 1.5 1 0 0 1 1 1 0 Clathrin, heavy-chain linker CPT PF07931.7 KOS18892.1 - 0.1 12.1 0.1 0.35 10.4 0.0 1.9 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_10 PF12846.2 KOS18892.1 - 0.12 11.8 0.2 4.4 6.6 0.1 2.5 1 1 0 2 2 2 0 AAA-like domain Macoilin PF09726.4 KOS18892.1 - 1.7 6.8 3.5 2.3 6.3 2.4 1.1 1 0 0 1 1 1 0 Transmembrane protein WD40 PF00400.27 KOS18893.1 - 4.9e-52 172.0 33.1 6e-10 38.6 0.0 12.8 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 KOS18893.1 - 1.1e-27 96.0 0.0 1.8e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KOS18893.1 - 1.2e-06 28.4 1.1 0.029 14.0 0.0 5.2 3 2 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KOS18893.1 - 6.5e-05 20.9 0.0 0.0012 16.7 0.0 2.4 2 1 0 2 2 2 1 IKI3 family Nup160 PF11715.3 KOS18893.1 - 0.00013 20.2 0.6 0.1 10.6 0.0 3.8 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 KOS18893.1 - 0.00067 18.8 0.2 2.9 6.9 0.0 4.0 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal DUF4243 PF14027.1 KOS18894.1 - 1.5e-59 202.1 0.1 1.7e-59 201.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) NAP PF00956.13 KOS18895.1 - 2.8e-48 164.1 10.1 2.8e-48 164.1 7.0 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) BUD22 PF09073.5 KOS18895.1 - 0.0058 15.7 13.7 0.0085 15.2 9.5 1.2 1 0 0 1 1 1 1 BUD22 DUF4363 PF14276.1 KOS18895.1 - 0.078 12.6 0.3 0.21 11.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) CutC PF03932.9 KOS18896.1 - 1.1e-25 90.1 0.0 3.6e-17 62.2 0.0 2.1 1 1 1 2 2 2 2 CutC family Fungal_trans PF04082.13 KOS18897.1 - 5.3e-15 54.9 0.1 8.3e-15 54.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.27 KOS18898.1 - 1.7e-25 87.9 5.5 3.3e-07 29.9 0.0 6.0 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KOS18898.1 - 0.0059 16.0 3.3 0.15 11.4 2.2 2.6 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 KOS18898.1 - 0.009 15.4 0.1 1.1 8.8 0.0 3.4 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.1 KOS18898.1 - 0.11 12.7 0.3 0.11 12.7 0.2 5.8 6 1 1 7 7 7 0 PQQ-like domain Nup160 PF11715.3 KOS18898.1 - 0.17 9.9 0.4 0.44 8.6 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Glyco_transf_15 PF01793.11 KOS18899.1 - 1.1e-127 425.5 10.2 1.3e-127 425.2 7.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Spc97_Spc98 PF04130.8 KOS18900.1 - 1.5e-66 224.8 0.0 1.9e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 KOS18900.1 - 9.3e-05 20.7 0.0 0.00064 17.9 0.0 1.9 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 BCDHK_Adom3 PF10436.4 KOS18901.1 - 1.2e-44 151.6 0.0 2e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KOS18901.1 - 3.9e-11 42.6 0.0 9.5e-08 31.7 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KOS18901.1 - 0.00022 20.9 0.0 0.00042 19.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KOS18901.1 - 0.084 12.6 0.0 0.72 9.6 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Septin PF00735.13 KOS18902.1 - 6.1e-117 389.6 0.4 9.1e-117 389.0 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KOS18902.1 - 5.4e-07 29.5 0.0 9.5e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KOS18902.1 - 4.9e-06 26.1 0.8 8e-05 22.1 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KOS18902.1 - 1.6e-05 24.1 0.0 4.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KOS18902.1 - 0.002 18.6 0.1 0.01 16.3 0.1 2.2 1 1 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 KOS18902.1 - 0.003 17.6 0.6 0.0085 16.2 0.0 2.2 2 2 0 2 2 2 1 AAA domain AAA_24 PF13479.1 KOS18902.1 - 0.0032 17.0 0.1 0.0065 16.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 KOS18902.1 - 0.0046 16.0 0.0 0.0096 15.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 KOS18902.1 - 0.0058 15.4 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 KOS18902.1 - 0.0069 15.8 0.0 0.018 14.5 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 KOS18902.1 - 0.011 15.0 0.1 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 KOS18902.1 - 0.024 14.0 0.4 0.076 12.3 0.3 1.9 2 1 0 2 2 1 0 Ras family T2SE PF00437.15 KOS18902.1 - 0.025 13.4 0.4 0.066 12.1 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.7 KOS18902.1 - 0.042 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ArgK PF03308.11 KOS18902.1 - 0.043 12.5 2.1 2.4 6.8 0.0 3.0 3 0 0 3 3 3 0 ArgK protein Dynamin_N PF00350.18 KOS18902.1 - 0.047 13.5 6.5 0.81 9.4 0.0 3.1 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.1 KOS18902.1 - 0.047 13.6 2.3 0.18 11.7 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.9 KOS18902.1 - 0.048 12.6 1.8 0.095 11.6 1.3 1.7 1 1 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.22 KOS18902.1 - 0.057 13.7 0.2 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.21 KOS18902.1 - 0.068 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2968 PF11180.3 KOS18902.1 - 0.086 12.2 5.4 0.22 10.9 3.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) PduV-EutP PF10662.4 KOS18902.1 - 0.1 12.0 1.2 2.5 7.6 0.2 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 KOS18902.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Val_tRNA-synt_C PF10458.4 KOS18902.1 - 0.4 10.7 5.6 0.13 12.3 0.5 2.6 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Atg14 PF10186.4 KOS18902.1 - 0.65 8.8 5.9 1.5 7.7 4.1 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Myc-LZ PF02344.10 KOS18902.1 - 1.1 8.9 8.9 0.34 10.5 1.6 2.5 2 0 0 2 2 2 0 Myc leucine zipper domain C2 PF00168.25 KOS18903.1 - 4.7e-19 68.0 0.0 1.8e-13 50.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain RNase_P_pop3 PF08228.6 KOS18905.1 - 1e-08 35.1 0.0 2.8e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 RNase P subunit Pop3 p47_phox_C PF08944.6 KOS18905.1 - 8.1 6.7 7.9 0.72 10.0 2.1 1.8 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain Brix PF04427.13 KOS18907.1 - 4.9e-39 133.9 0.1 7.1e-39 133.4 0.1 1.2 1 0 0 1 1 1 1 Brix domain Sporozoite_P67 PF05642.6 KOS18907.1 - 0.51 8.1 2.9 0.69 7.7 2.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOC3p PF07540.6 KOS18908.1 - 3.1e-31 107.5 0.0 3.1e-31 107.5 0.0 3.0 4 0 0 4 4 4 1 Nucleolar complex-associated protein CBF PF03914.12 KOS18908.1 - 1.5e-26 92.8 0.4 1.4e-24 86.4 0.0 2.5 2 0 0 2 2 2 2 CBF/Mak21 family Epimerase PF01370.16 KOS18909.1 - 1.3e-57 195.0 0.1 1.6e-57 194.6 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KOS18909.1 - 3.3e-22 78.5 0.0 4.3e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KOS18909.1 - 6.8e-21 74.3 0.2 2.5e-20 72.4 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KOS18909.1 - 9e-20 70.7 0.0 1.3e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KOS18909.1 - 9.8e-20 70.6 0.0 1.3e-18 66.9 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KOS18909.1 - 3.7e-08 33.5 0.0 8.4e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KOS18909.1 - 0.00072 19.5 0.0 0.075 12.9 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase TPT PF03151.11 KOS18910.1 - 4e-12 46.0 22.9 3.5e-11 42.9 7.1 3.4 2 2 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KOS18910.1 - 3.9 7.5 27.4 0.57 10.2 3.5 3.6 2 1 1 3 3 3 0 EamA-like transporter family EmrE PF13536.1 KOS18910.1 - 5.4 7.2 26.1 0.085 13.0 4.1 3.4 2 2 1 4 4 4 0 Multidrug resistance efflux transporter Pkinase PF00069.20 KOS18911.1 - 3.4e-71 239.4 0.0 6.8e-71 238.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS18911.1 - 9.3e-31 106.8 0.0 1.4e-22 80.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KOS18911.1 - 1.7e-06 27.2 0.0 0.34 9.8 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.9 KOS18911.1 - 0.021 13.8 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_2b PF00587.20 KOS18912.1 - 1.8e-21 76.4 0.0 2.6e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KOS18912.1 - 1.4e-11 44.3 2.4 3e-11 43.2 1.6 1.6 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DSHCT PF08148.7 KOS18913.1 - 1e-59 200.7 0.4 1.8e-59 199.9 0.3 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KOS18913.1 - 5.9e-21 74.6 0.0 2.4e-20 72.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 KOS18913.1 - 1.7e-06 27.4 0.1 0.00016 20.9 0.0 2.3 2 0 0 2 2 2 2 rRNA-processing arch domain Helicase_C PF00271.26 KOS18913.1 - 8.8e-06 25.4 0.0 2.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS18913.1 - 0.007 16.2 0.2 0.96 9.2 0.1 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Transket_pyr PF02779.19 KOS18914.1 - 4.9e-45 153.2 0.0 7.8e-45 152.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KOS18914.1 - 1.2e-34 118.8 0.0 3.5e-34 117.4 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain zf-C2H2_jaz PF12171.3 KOS18915.1 - 1.8e-05 24.7 3.0 2.8e-05 24.1 2.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS18915.1 - 0.0042 17.2 0.6 0.0071 16.5 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KOS18915.1 - 0.061 13.4 0.9 0.093 12.8 0.6 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KOS18915.1 - 0.073 13.4 1.0 0.14 12.5 0.7 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS18915.1 - 0.12 12.7 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1691 PF07950.6 KOS18916.1 - 4.6e-39 132.7 6.0 3.4e-23 81.6 0.8 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Herpes_US9 PF06072.6 KOS18916.1 - 0.042 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 ABC_tran PF00005.22 KOS18917.1 - 2.1e-31 109.0 0.0 3e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC_ATPase PF09818.4 KOS18917.1 - 1.3e-05 23.9 0.0 5.1e-05 22.0 0.0 2.0 2 1 1 3 3 3 1 Predicted ATPase of the ABC class SMC_N PF02463.14 KOS18917.1 - 2.8e-05 23.4 0.1 0.0015 17.8 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KOS18917.1 - 4e-05 23.7 0.0 0.23 11.4 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KOS18917.1 - 6.4e-05 23.0 0.9 0.00014 21.9 0.6 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KOS18917.1 - 0.00081 20.2 0.1 0.0011 19.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KOS18917.1 - 0.0013 18.8 0.2 0.02 14.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KOS18917.1 - 0.0029 16.8 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KOS18917.1 - 0.0051 16.7 0.3 0.021 14.7 0.2 2.0 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 KOS18917.1 - 0.018 14.7 0.0 0.066 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KOS18917.1 - 0.018 14.5 0.1 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KOS18917.1 - 0.019 14.3 0.0 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KOS18917.1 - 0.027 14.3 0.0 0.9 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KOS18917.1 - 0.034 14.3 0.0 3.6 7.7 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KOS18917.1 - 0.036 13.5 0.2 0.081 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 KOS18917.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KOS18917.1 - 0.055 12.5 0.0 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.13 KOS18917.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 KOS18917.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.18 KOS18918.1 - 7.7e-42 143.5 10.5 9.1e-42 143.3 7.3 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region zf-DHHC PF01529.15 KOS18918.1 - 1.5 8.2 5.7 4.2 6.7 1.2 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase DnaJ PF00226.26 KOS18920.1 - 4.2e-20 71.2 4.2 4.2e-20 71.2 2.9 2.8 2 1 0 2 2 2 1 DnaJ domain Ald_Xan_dh_C2 PF02738.13 KOS18920.1 - 2.6 6.2 10.1 6.6 4.9 4.2 2.4 3 0 0 3 3 3 0 Molybdopterin-binding domain of aldehyde dehydrogenase HlyD PF00529.15 KOS18920.1 - 6.3 6.0 20.7 13 5.0 14.3 1.5 1 0 0 1 1 1 0 HlyD family secretion protein Sterol_MT_C PF08498.5 KOS18921.1 - 3.7e-24 84.4 0.1 5.7e-24 83.8 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KOS18921.1 - 4.3e-20 71.9 0.0 8.4e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS18921.1 - 7.9e-17 61.2 0.0 1.1e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS18921.1 - 2.1e-15 56.8 0.0 3.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS18921.1 - 5.2e-12 46.3 0.0 1.1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS18921.1 - 2.5e-11 43.9 0.0 4.5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KOS18921.1 - 4.1e-11 42.4 0.0 5.6e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KOS18921.1 - 3.1e-10 40.3 0.0 5.8e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KOS18921.1 - 3.5e-09 36.1 0.0 5.6e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KOS18921.1 - 7e-08 32.5 0.0 2.3e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KOS18921.1 - 0.00014 21.4 0.1 0.00022 20.8 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 KOS18921.1 - 0.00025 20.4 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KOS18921.1 - 0.0037 16.4 0.0 0.0083 15.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 KOS18921.1 - 0.0058 15.8 0.0 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 KOS18921.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 KOS18921.1 - 0.019 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_32 PF13679.1 KOS18921.1 - 0.043 13.4 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KOS18921.1 - 0.045 12.7 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.7 KOS18921.1 - 0.047 13.0 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RRM_1 PF00076.17 KOS18922.1 - 1.3e-10 40.7 0.0 2.1e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS18922.1 - 1.8e-09 37.3 0.0 3.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS18922.1 - 3.7e-06 26.8 0.0 6.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KOS18922.1 - 0.0014 18.4 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 KOS18922.1 - 0.0022 17.7 0.0 0.0051 16.5 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Syntaxin-6_N PF09177.6 KOS18923.1 - 8.7e-25 86.9 0.3 6.7e-24 84.1 0.0 2.3 2 1 1 3 3 3 1 Syntaxin 6, N-terminal SNARE PF05739.14 KOS18923.1 - 4.6e-13 48.6 5.5 1e-12 47.5 2.6 2.3 2 0 0 2 2 2 1 SNARE domain CCDC155 PF14662.1 KOS18923.1 - 0.1 12.1 2.1 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Cast PF10174.4 KOS18923.1 - 0.12 10.4 1.2 0.3 9.0 0.8 1.7 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Filament PF00038.16 KOS18923.1 - 0.13 11.7 4.9 0.24 10.8 0.6 2.3 2 1 0 2 2 2 0 Intermediate filament protein MCPsignal PF00015.16 KOS18923.1 - 0.13 11.7 1.4 0.79 9.2 0.0 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF972 PF06156.8 KOS18923.1 - 0.15 12.3 0.6 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Baculo_PEP_C PF04513.7 KOS18923.1 - 0.16 11.7 0.9 1.8 8.3 0.1 2.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 KOS18923.1 - 0.26 11.5 1.2 20 5.5 0.1 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HrpB7 PF09486.5 KOS18923.1 - 0.45 10.4 10.1 2.7 7.9 2.4 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4164 PF13747.1 KOS18923.1 - 2 8.6 7.1 7.3 6.7 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Methyltransf_32 PF13679.1 KOS18924.1 - 2.8e-18 65.9 0.0 5.3e-18 65.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS18924.1 - 0.054 14.0 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain ACT_7 PF13840.1 KOS18925.1 - 8.1e-21 73.3 0.1 2.5e-14 52.5 0.0 2.4 2 0 0 2 2 2 2 ACT domain Zip PF02535.17 KOS18925.1 - 0.0014 17.6 10.0 0.0021 17.0 6.9 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter SelP_N PF04592.9 KOS18925.1 - 0.0045 16.3 13.7 0.0077 15.6 9.5 1.3 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Mito_fiss_reg PF05308.6 KOS18925.1 - 2.1 7.6 6.9 4.1 6.6 4.8 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator UPF0029 PF01205.14 KOS18926.1 - 1.9e-25 88.6 0.0 3.1e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KOS18926.1 - 9.6e-08 31.9 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain ATP-synt_ab PF00006.20 KOS18927.1 - 1.4e-112 374.4 0.0 1.9e-112 373.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KOS18927.1 - 1.4e-16 60.9 0.2 2.7e-16 60.0 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KOS18927.1 - 9e-16 57.8 2.8 2.5e-14 53.2 2.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Metallophos PF00149.23 KOS18929.1 - 8.8e-12 44.8 0.3 1.5e-11 44.1 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase C-C_Bond_Lyase PF15617.1 KOS18929.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Pet127 PF08634.5 KOS18930.1 - 9.9e-119 395.5 0.9 1.5e-118 394.9 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 RNB PF00773.14 KOS18931.1 - 1e-64 218.9 0.0 4.6e-64 216.7 0.0 2.1 2 0 0 2 2 2 1 RNB domain DUF4239 PF14023.1 KOS18931.1 - 0.074 12.4 0.1 0.18 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) GLE1 PF07817.8 KOS18932.1 - 4.5e-22 78.2 0.0 1.3e-21 76.6 0.0 1.7 1 1 0 1 1 1 1 GLE1-like protein PAT1 PF09770.4 KOS18932.1 - 2.4 6.2 19.4 3.3 5.8 13.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATP-synt_ab PF00006.20 KOS18933.1 - 3.4e-62 209.7 0.0 4.8e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 KOS18933.1 - 3.1e-25 88.1 0.5 2.6e-24 85.2 0.3 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 KOS18933.1 - 1.4e-24 86.7 0.8 2.7e-24 85.8 0.3 1.7 2 0 0 2 2 1 1 ATP synthase alpha/beta chain, C terminal domain MobB PF03205.9 KOS18933.1 - 0.0044 16.7 0.1 0.87 9.2 0.0 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KOS18933.1 - 0.0081 15.5 0.1 0.036 13.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KOS18933.1 - 0.0086 15.7 0.0 0.022 14.4 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase KaiC PF06745.8 KOS18933.1 - 0.013 14.6 0.1 0.02 13.9 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA PF00004.24 KOS18933.1 - 0.014 15.6 0.1 0.35 11.0 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KOS18933.1 - 0.018 14.2 0.1 0.033 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KOS18933.1 - 0.02 15.0 0.0 0.098 12.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 KOS18933.1 - 0.025 14.2 0.1 0.063 12.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 KOS18933.1 - 0.056 13.4 0.2 0.28 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 KOS18933.1 - 0.065 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 KOS18933.1 - 0.18 10.6 0.5 0.61 8.8 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain Aldedh PF00171.17 KOS18934.1 - 2.7e-160 533.7 0.0 3e-160 533.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAM176 PF14851.1 KOS18935.1 - 0.0049 16.5 0.0 0.0092 15.6 0.0 1.4 1 0 0 1 1 1 1 FAM176 family RRF PF01765.14 KOS18937.1 - 2.9e-23 82.1 3.2 1.2e-21 76.9 3.2 2.0 2 0 0 2 2 2 1 Ribosome recycling factor DUF1870 PF08965.5 KOS18937.1 - 0.089 12.4 0.5 0.16 11.6 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) ATP-synt_B PF00430.13 KOS18937.1 - 0.21 11.3 7.8 0.46 10.2 5.4 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) SUR7 PF06687.7 KOS18938.1 - 3e-31 108.6 5.5 3.6e-31 108.3 3.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Shisa PF13908.1 KOS18938.1 - 0.017 15.2 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Metallophos PF00149.23 KOS18939.1 - 4.5e-39 133.9 0.3 6.9e-39 133.3 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ADH_N PF08240.7 KOS18940.1 - 9.8e-28 96.0 3.4 2.1e-27 95.0 2.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KOS18940.1 - 3.5e-13 49.2 0.1 6.8e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 KOS18940.1 - 0.041 13.6 0.2 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 S1-like 3HCDH_N PF02737.13 KOS18940.1 - 0.048 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KOS18940.1 - 0.056 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain WD40 PF00400.27 KOS18941.1 - 6e-19 67.1 1.9 0.00023 20.8 0.0 9.4 9 0 0 9 9 9 5 WD domain, G-beta repeat HATPase_c PF02518.21 KOS18942.1 - 1e-21 76.7 0.0 1.9e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KOS18942.1 - 1.6e-20 73.2 0.1 3.1e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 KOS18942.1 - 2.9e-14 53.3 0.0 7.8e-11 42.2 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KOS18942.1 - 2.1e-13 50.2 0.0 7.7e-06 25.9 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 KOS18942.1 - 2.9e-08 33.5 0.0 8.4e-08 31.9 0.0 1.9 1 0 0 1 1 1 1 PAS fold HisKA PF00512.20 KOS18942.1 - 3.2e-07 30.2 1.3 4.6e-07 29.7 0.1 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 KOS18942.1 - 0.00013 21.9 0.5 0.0004 20.4 0.1 2.2 2 0 0 2 2 2 1 PAS fold GAF_2 PF13185.1 KOS18942.1 - 0.0051 17.3 0.1 0.028 14.8 0.0 2.2 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.1 KOS18942.1 - 0.023 14.8 0.0 0.074 13.1 0.0 1.9 2 0 0 2 2 2 0 GAF domain PAS_8 PF13188.1 KOS18942.1 - 0.055 13.3 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 PAS domain PH_6 PF15406.1 KOS18943.1 - 2e-33 114.7 0.3 2e-33 114.7 0.2 2.8 3 0 0 3 3 3 1 Pleckstrin homology domain STT3 PF02516.9 KOS18944.1 - 2.9e-130 435.4 35.0 4.7e-125 418.3 23.0 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit CPSase_L_D2 PF02786.12 KOS18945.1 - 6.7e-81 270.5 0.3 1e-80 269.9 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KOS18945.1 - 2.5e-65 219.6 0.0 4.5e-65 218.7 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KOS18945.1 - 2.2e-35 121.0 0.0 4.9e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KOS18945.1 - 5.4e-31 106.7 0.0 2.2e-30 104.7 0.0 2.1 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KOS18945.1 - 6.7e-26 91.4 0.0 1.4e-25 90.3 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 KOS18945.1 - 1.1e-18 66.6 1.2 2.9e-18 65.2 0.8 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KOS18945.1 - 1.3e-18 67.3 0.1 2.4e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KOS18945.1 - 2.3e-15 56.2 0.0 1.4e-14 53.6 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KOS18945.1 - 1.8e-11 43.4 0.5 1.9e-06 27.4 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KOS18945.1 - 8.9e-10 38.2 0.0 1.6e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 KOS18945.1 - 8e-08 31.9 0.0 2.5e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 KOS18945.1 - 1e-06 28.2 0.0 1.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 KOS18945.1 - 2.2e-05 23.7 0.0 0.087 11.9 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 KOS18945.1 - 9.5e-05 22.3 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 KOS18945.1 - 0.00025 21.3 0.0 0.022 15.0 0.0 3.3 2 1 1 3 3 2 2 HlyD family secretion protein HlyD PF00529.15 KOS18945.1 - 0.00064 19.1 0.0 0.055 12.7 0.0 2.3 2 0 0 2 2 2 1 HlyD family secretion protein DUF2118 PF09891.4 KOS18945.1 - 0.0091 15.7 0.2 0.042 13.5 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.1 KOS18945.1 - 0.013 15.1 0.5 0.034 13.8 0.3 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain NQRA PF05896.6 KOS18945.1 - 0.019 14.1 0.1 0.035 13.2 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Rieske PF00355.21 KOS18945.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain MPC PF03650.8 KOS18946.1 - 9.8e-36 122.3 0.0 1.1e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) EutH PF04346.7 KOS18946.1 - 0.027 13.4 0.0 0.031 13.2 0.0 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH Corona_S2 PF01601.11 KOS18947.1 - 4.5e-05 21.7 11.1 6.1e-05 21.3 7.7 1.1 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein EVI2A PF05399.6 KOS18947.1 - 3.4 6.8 4.0 5.1 6.2 2.7 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) RCR PF12273.3 KOS18948.1 - 1.5e-09 38.4 6.8 3.7e-09 37.2 4.7 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4131 PF13567.1 KOS18948.1 - 0.0066 15.8 0.1 0.009 15.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) TFIIA PF03153.8 KOS18949.1 - 0.88 9.4 9.7 1.1 9.0 6.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ORC6 PF05460.8 KOS18950.1 - 2.1 7.3 9.1 3.3 6.7 6.3 1.3 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Fungal_trans_2 PF11951.3 KOS18951.1 - 4.4e-75 252.6 0.4 5.3e-75 252.3 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain SAM_2 PF07647.12 KOS18952.1 - 2e-05 24.3 0.0 4.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 KOS18952.1 - 0.00011 22.3 0.0 0.00032 20.8 0.0 1.8 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.25 KOS18952.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Sod_Fe_C PF02777.13 KOS18953.1 - 4.2e-09 36.1 0.0 0.00071 19.3 0.0 2.3 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KOS18953.1 - 0.034 14.4 0.1 0.052 13.8 0.1 1.3 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF3661 PF12400.3 KOS18954.1 - 2e-30 105.5 5.6 4.9e-30 104.2 3.9 1.6 1 1 0 1 1 1 1 Vaculolar membrane protein Zip PF02535.17 KOS18954.1 - 0.061 12.3 0.1 0.061 12.3 0.0 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Cofilin_ADF PF00241.15 KOS18955.1 - 8.7e-16 57.9 0.0 1.1e-07 31.7 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein LPAM_2 PF13627.1 KOS18956.1 - 0.19 11.4 2.9 0.59 9.9 2.0 1.9 1 1 0 1 1 1 0 Prokaryotic lipoprotein-attachment site PepSY_2 PF13670.1 KOS18956.1 - 2.9 7.8 4.8 2.1 8.3 0.2 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Vps54 PF07928.7 KOS18957.1 - 2.1e-46 157.3 0.2 6.9e-46 155.7 0.0 2.0 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 KOS18957.1 - 5e-06 25.6 2.3 1.1e-05 24.5 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) LUC7 PF03194.10 KOS18957.1 - 0.15 11.5 0.7 0.3 10.5 0.5 1.4 1 0 0 1 1 1 0 LUC7 N_terminus COG2 PF06148.6 KOS18957.1 - 1.4 8.8 4.9 0.94 9.3 1.6 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prp19_bind PF06991.6 KOS18958.1 - 1.1e-40 139.6 20.5 1.1e-40 139.6 14.2 2.1 1 1 1 2 2 2 2 Splicing factor, Prp19-binding domain Pol_alpha_B_N PF08418.5 KOS18959.1 - 2.1e-51 174.9 0.0 1.1e-50 172.5 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KOS18959.1 - 1.9e-36 125.3 0.0 2.6e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B MAP7 PF05672.6 KOS18960.1 - 0.38 10.1 20.2 0.019 14.3 5.6 2.4 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family RmlD_sub_bind PF04321.12 KOS18961.1 - 2.7e-54 184.0 0.0 3.3e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KOS18961.1 - 8.2e-22 77.7 0.0 1.1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KOS18961.1 - 4.2e-10 38.9 0.0 1.4e-09 37.3 0.0 1.8 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 KOS18961.1 - 1.4e-05 24.1 0.0 0.00018 20.5 0.0 2.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KOS18961.1 - 7.6e-05 21.5 0.0 0.0001 21.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KOS18961.1 - 0.00016 21.7 0.3 0.00029 20.9 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KOS18961.1 - 0.17 11.7 1.1 3.1 7.7 0.8 2.3 1 1 0 1 1 1 0 short chain dehydrogenase APC8 PF04049.8 KOS18962.1 - 5.2e-50 168.8 1.9 6.2e-50 168.6 0.3 1.9 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 KOS18962.1 - 3.3e-20 70.7 4.4 7.5e-05 22.1 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 KOS18962.1 - 3.5e-19 68.2 5.8 1.3e-06 27.9 0.0 6.7 4 1 2 6 6 6 3 TPR repeat TPR_8 PF13181.1 KOS18962.1 - 8.1e-15 53.4 5.8 0.00027 20.4 0.0 6.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS18962.1 - 2.9e-13 48.6 16.2 0.03 14.2 0.0 9.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 KOS18962.1 - 1.9e-09 37.2 11.1 0.026 15.1 0.0 9.0 8 2 2 10 10 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 KOS18962.1 - 7.9e-09 35.3 16.3 8.5e-05 22.4 0.3 6.5 3 1 4 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 KOS18962.1 - 1.6e-06 28.1 3.5 0.64 10.1 0.3 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KOS18962.1 - 3.9e-06 27.3 23.9 3.6e-05 24.3 0.0 7.9 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 KOS18962.1 - 5.3e-05 22.7 6.6 0.097 12.5 0.0 5.3 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KOS18962.1 - 0.00014 21.8 0.2 2.6 8.4 0.0 5.6 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.2 KOS18962.1 - 0.0012 18.6 1.0 0.07 12.9 0.1 3.1 1 1 1 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_19 PF14559.1 KOS18962.1 - 0.0062 16.8 8.5 14 6.0 0.0 6.3 7 1 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 KOS18962.1 - 0.029 14.7 22.8 21 5.8 0.4 9.6 11 0 0 11 11 11 0 Tetratricopeptide repeat DUF2424 PF10340.4 KOS18962.1 - 0.067 11.8 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Senescence_reg PF04520.8 KOS18962.1 - 0.071 13.6 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Senescence regulator TPR_9 PF13371.1 KOS18962.1 - 0.49 10.2 15.4 1.7 8.5 0.2 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat Dicty_REP PF05086.7 KOS18962.1 - 0.92 7.1 3.7 1.3 6.6 2.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 KOS18962.1 - 2.1 8.1 11.7 4.5 7.0 8.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Med3 PF11593.3 KOS18962.1 - 3.3 6.8 10.0 5.1 6.2 6.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal polyprenyl_synt PF00348.12 KOS18963.1 - 5.6e-66 222.0 0.0 7.2e-66 221.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Amidase02_C PF12123.3 KOS18964.1 - 0.11 12.1 1.7 0.97 9.1 0.0 2.5 2 1 1 3 3 3 0 N-acetylmuramoyl-l-alanine amidase Methyltransf_15 PF09445.5 KOS18966.1 - 1.3e-36 125.6 0.0 2.5e-35 121.4 0.0 2.1 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KOS18966.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS18966.1 - 0.012 16.1 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 KOS18966.1 - 0.06 12.9 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 GRASP55_65 PF04495.9 KOS18967.1 - 9.2e-45 152.0 0.0 3.2e-44 150.2 0.0 1.7 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Trs65 PF12735.2 KOS18968.1 - 8.4e-62 209.2 0.0 1.3e-61 208.5 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 FF PF01846.14 KOS18969.1 - 4.8e-48 160.9 12.8 7.9e-14 51.3 0.0 5.9 5 0 0 5 5 5 5 FF domain WW PF00397.21 KOS18969.1 - 1.1e-17 63.5 16.3 2.4e-09 36.8 2.8 2.6 2 0 0 2 2 2 2 WW domain Pox_A11 PF05061.8 KOS18969.1 - 0.43 9.6 2.7 0.21 10.6 0.1 1.7 2 0 0 2 2 2 0 Poxvirus A11 Protein Homeobox PF00046.24 KOS18970.1 - 4.8e-15 54.9 3.1 9.5e-15 53.9 2.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KOS18970.1 - 7.2e-05 22.4 2.3 0.00012 21.6 0.4 2.1 2 0 0 2 2 2 1 Homeobox KN domain SLD3 PF08639.5 KOS18971.1 - 7e-94 315.2 0.7 7e-94 315.2 0.5 1.7 2 0 0 2 2 2 1 DNA replication regulator SLD3 Peptidase_C15 PF01470.12 KOS18972.1 - 5.2e-06 26.4 0.0 1.4e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Pyroglutamyl peptidase HAD_2 PF13419.1 KOS18973.1 - 7.7e-15 55.5 0.0 5.3e-14 52.8 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS18973.1 - 7.1e-11 42.9 0.0 1.9e-05 25.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KOS18973.1 - 1.4e-10 40.7 0.0 2.5e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 KOS18973.1 - 0.0066 16.6 0.0 0.023 14.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GHL6 PF14871.1 KOS18973.1 - 0.023 14.7 0.8 0.03 14.3 0.0 1.5 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 DAD PF02109.11 KOS18974.1 - 6e-47 158.3 2.0 7.6e-47 158.0 1.4 1.1 1 0 0 1 1 1 1 DAD family Tmemb_14 PF03647.8 KOS18975.1 - 5e-23 81.3 7.8 6.2e-23 81.0 5.4 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF1275 PF06912.6 KOS18975.1 - 0.037 13.2 1.6 0.045 12.9 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) CytB6-F_Fe-S PF08802.5 KOS18975.1 - 9.5 6.3 8.7 5.1 7.1 0.5 3.2 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit HLH PF00010.21 KOS18976.1 - 2.6e-12 46.2 0.2 5.6e-12 45.1 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DivIC PF04977.10 KOS18976.1 - 0.013 14.9 0.7 0.027 13.9 0.5 1.5 1 0 0 1 1 1 0 Septum formation initiator Pox_A30L_A26L PF06086.7 KOS18976.1 - 0.14 11.5 0.1 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein AAA_32 PF13654.1 KOS18976.1 - 0.19 10.3 1.9 0.27 9.8 1.3 1.1 1 0 0 1 1 1 0 AAA domain BRO1 PF03097.13 KOS18977.1 - 2.7e-05 23.1 0.0 3.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain Alg6_Alg8 PF03155.10 KOS18978.1 - 1.2e-129 433.2 17.9 3.4e-81 273.4 5.7 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Ribosomal_60s PF00428.14 KOS18979.1 - 1.9e-26 92.2 17.4 2.2e-26 92.0 12.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Gly-zipper_OmpA PF13436.1 KOS18979.1 - 0.081 12.5 7.1 0.11 12.1 4.9 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF1749 PF08538.5 KOS18980.1 - 3.8e-79 265.7 0.0 4.5e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KOS18980.1 - 5e-16 59.2 0.0 6e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS18980.1 - 4.3e-09 36.2 0.0 9.3e-09 35.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS18980.1 - 7.2e-07 28.9 0.2 0.00048 19.7 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KOS18980.1 - 0.011 14.9 0.0 0.49 9.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 KOS18980.1 - 0.014 14.9 0.0 0.083 12.4 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase PGAP1 PF07819.8 KOS18980.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_9 PF10081.4 KOS18980.1 - 0.074 11.7 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta-hydrolase family DUF2305 PF10230.4 KOS18980.1 - 0.11 11.9 0.1 0.79 9.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) ABC_membrane PF00664.18 KOS18981.1 - 3.1e-83 279.3 28.9 1.7e-45 155.5 8.1 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KOS18981.1 - 2.6e-50 170.2 0.0 3.8e-30 104.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KOS18981.1 - 1.3e-09 37.6 5.3 0.0018 17.5 0.1 4.2 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain Miro PF08477.8 KOS18981.1 - 0.00013 22.3 0.1 0.6 10.6 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 KOS18981.1 - 0.00021 21.2 0.2 0.51 10.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KOS18981.1 - 0.0011 18.9 3.4 0.091 12.7 0.2 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 KOS18981.1 - 0.0012 18.3 0.8 0.71 9.4 0.0 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KOS18981.1 - 0.0012 18.2 0.0 0.38 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KOS18981.1 - 0.0015 18.5 0.8 9.9 6.0 0.0 4.5 4 1 1 5 5 5 0 AAA domain DUF258 PF03193.11 KOS18981.1 - 0.0024 17.0 0.1 0.75 8.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KOS18981.1 - 0.0051 16.6 2.1 0.2 11.4 0.1 2.5 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.1 KOS18981.1 - 0.0052 17.1 0.1 1.3 9.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 KOS18981.1 - 0.0059 16.4 0.4 0.59 9.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 KOS18981.1 - 0.014 14.8 0.0 5 6.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 KOS18981.1 - 0.014 14.9 0.8 4.3 6.8 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 KOS18981.1 - 0.029 14.5 1.0 9 6.4 0.0 3.4 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KOS18981.1 - 0.17 10.9 0.1 7 5.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF2085 PF09858.4 KOS18981.1 - 0.28 11.2 5.7 0.35 10.9 0.6 3.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) DUF2841 PF11001.3 KOS18982.1 - 8.5e-40 135.5 2.6 1.3e-39 134.9 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) PQ-loop PF04193.9 KOS18983.1 - 3.3e-37 125.8 11.8 3.7e-19 68.0 0.4 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF4381 PF14316.1 KOS18983.1 - 0.1 12.7 1.8 0.3 11.1 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF3742 PF12553.3 KOS18983.1 - 0.28 11.6 1.8 6.6 7.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) NUDIX PF00293.23 KOS18984.1 - 3.3e-17 62.3 0.1 5.7e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 KOS18984.1 - 1e-10 41.7 0.3 2.8e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 KOS18984.1 - 5.5e-08 32.1 0.7 1.1e-07 31.2 0.5 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Pex2_Pex12 PF04757.9 KOS18985.1 - 1.6e-40 138.9 2.5 2e-40 138.6 1.8 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 KOS18985.1 - 0.00022 21.0 4.0 0.00045 20.0 2.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KOS18985.1 - 0.042 13.8 9.4 0.064 13.2 4.0 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KOS18985.1 - 0.043 13.5 0.7 0.23 11.2 0.5 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.20 KOS18985.1 - 0.065 12.9 1.7 0.15 11.7 1.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MFS_1_like PF12832.2 KOS18986.1 - 1.1e-15 57.1 0.0 1.1e-15 57.1 0.0 2.7 3 1 0 3 3 3 1 MFS_1 like family Cytochrom_B558a PF05038.8 KOS18986.1 - 0.053 13.1 0.3 0.15 11.6 0.2 1.7 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Fungal_trans PF04082.13 KOS18988.1 - 1.2e-07 30.8 0.2 2.3e-07 29.9 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS18988.1 - 2.6e-05 24.0 10.4 5.5e-05 22.9 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRA1 PF07304.6 KOS18988.1 - 0.11 12.2 1.3 8.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) HMG_box PF00505.14 KOS18989.1 - 4e-07 30.2 2.1 1.2e-06 28.6 0.2 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KOS18989.1 - 0.0014 18.9 1.0 0.0065 16.8 0.1 2.5 2 0 0 2 2 2 1 HMG-box domain Het-C PF07217.6 KOS18990.1 - 3.4e-250 831.4 0.0 4.9e-250 830.9 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C zf-RING_2 PF13639.1 KOS18991.1 - 2.3e-08 33.7 11.4 3.9e-08 32.9 7.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KOS18991.1 - 0.00014 21.9 5.5 0.0003 20.8 3.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KOS18991.1 - 0.0026 17.3 11.4 0.0047 16.5 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KOS18991.1 - 0.016 15.0 5.9 0.032 14.0 4.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KOS18991.1 - 0.075 13.0 12.3 0.14 12.2 8.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS18991.1 - 0.13 12.0 11.3 0.21 11.3 7.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain DUF1049 PF06305.6 KOS18991.1 - 0.63 9.5 4.3 0.12 11.8 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Macoilin PF09726.4 KOS18991.1 - 0.91 7.7 2.7 1.5 7.0 1.9 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF2217 PF10265.4 KOS18991.1 - 2.4 6.8 10.0 1.3 7.6 0.9 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Ada3 PF10198.4 KOS18993.1 - 7.2e-45 151.9 0.1 1.7e-44 150.7 0.1 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Amidohydro_1 PF01979.15 KOS18994.1 - 1.3e-59 202.5 0.8 2.1e-59 201.8 0.5 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 KOS18994.1 - 1.9e-54 182.9 2.2 1.9e-54 182.9 1.5 1.8 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 KOS18994.1 - 1.1e-42 143.8 0.4 2.8e-42 142.6 0.1 1.8 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 KOS18994.1 - 1.9e-37 127.2 0.1 4.5e-37 126.0 0.0 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 KOS18994.1 - 9.6e-08 31.7 3.2 2.7e-07 30.3 2.2 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KOS18994.1 - 4.1e-05 22.9 0.1 0.0004 19.7 0.0 2.3 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_2 PF04909.9 KOS18994.1 - 0.0051 16.4 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase ATP_transf PF09830.4 KOS18995.1 - 2e-17 62.6 0.0 3.2e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase Scs3p PF10261.4 KOS18996.1 - 2.5e-61 206.7 0.7 3.3e-61 206.3 0.5 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM SSP160 PF06933.6 KOS18996.1 - 4.2 5.2 13.8 6 4.7 9.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CIMR PF00878.13 KOS18997.1 - 5.2e-09 36.0 0.0 0.00036 20.3 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 KOS18997.1 - 9.1e-09 34.7 0.0 1.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 KOS18997.1 - 4e-05 22.9 0.1 0.00028 20.2 0.1 2.3 1 1 0 1 1 1 1 Autophagy-related protein 27 Opi1 PF08618.5 KOS18997.1 - 0.027 13.3 2.1 0.047 12.6 1.5 1.3 1 0 0 1 1 1 0 Transcription factor Opi1 MBOAT_2 PF13813.1 KOS18999.1 - 1.2e-21 76.5 7.3 3.7e-21 74.9 5.1 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PseudoU_synth_1 PF01416.15 KOS19001.1 - 1.8e-23 82.9 0.1 2.7e-10 40.6 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase Med22 PF06179.7 KOS19002.1 - 2.4e-05 24.2 0.0 3.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex UPF0052 PF01933.13 KOS19003.1 - 3.3e-46 157.9 0.0 4.3e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Glyco_hydro_3 PF00933.16 KOS19004.1 - 7e-89 297.7 0.0 9.6e-89 297.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KOS19004.1 - 5.2e-51 173.3 0.3 1.2e-50 172.1 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KOS19004.1 - 4.9e-15 55.2 0.0 1e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Abhydrolase_6 PF12697.2 KOS19005.1 - 2.9e-17 63.3 2.4 2.9e-17 63.3 1.7 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS19005.1 - 4.7e-10 39.3 0.0 1.9e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KOS19005.1 - 3.1e-05 23.7 0.0 6.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KOS19005.1 - 0.00023 20.8 0.3 0.0026 17.3 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 KOS19005.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF3543 PF12063.3 KOS19006.1 - 1.7e-84 282.8 0.0 3.2e-84 281.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 KOS19006.1 - 6.1e-61 205.8 0.0 1.2e-60 204.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19006.1 - 4.3e-41 140.7 0.0 8.8e-41 139.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KOS19006.1 - 0.064 12.0 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Aminotran_3 PF00202.16 KOS19007.1 - 4e-105 351.3 0.0 5e-105 351.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KOS19007.1 - 4.8e-05 22.6 0.0 8.3e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Voltage_CLC PF00654.15 KOS19009.1 - 5.7e-76 255.8 28.2 1.8e-70 237.7 12.8 2.9 2 1 1 3 3 3 2 Voltage gated chloride channel TAT_signal PF10518.4 KOS19009.1 - 0.011 15.7 3.4 0.011 15.7 2.4 2.6 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence CBS PF00571.23 KOS19009.1 - 0.045 13.5 0.1 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 CBS domain Sas10 PF09368.5 KOS19010.1 - 1.2e-27 95.8 5.9 1.2e-27 95.8 4.1 2.5 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KOS19010.1 - 4.1e-12 46.1 0.0 1.3e-11 44.5 0.0 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Vps51 PF08700.6 KOS19011.1 - 1e-15 57.3 0.0 4.4e-15 55.2 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 GAGA_bind PF06217.7 KOS19011.1 - 0.22 11.4 3.1 0.47 10.3 2.2 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Ycf1 PF05758.7 KOS19011.1 - 0.59 7.7 4.4 0.082 10.6 0.4 1.4 2 0 0 2 2 2 0 Ycf1 NPR3 PF03666.8 KOS19011.1 - 3.2 6.1 5.8 5.2 5.4 4.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ECH PF00378.15 KOS19012.1 - 2.5e-22 79.2 0.5 2.9e-22 78.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family RNA_pol_I_A49 PF06870.7 KOS19013.1 - 5.5e-67 226.0 0.8 6.6e-67 225.7 0.6 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Pkinase PF00069.20 KOS19014.1 - 1.8e-06 27.3 0.0 2.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain TraC PF07820.7 KOS19015.1 - 0.0074 16.4 3.2 0.012 15.7 2.2 1.3 1 0 0 1 1 1 1 TraC-like protein Glycogen_syn PF05693.8 KOS19016.1 - 0 1148.1 0.0 0 1147.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KOS19016.1 - 5.7e-07 29.1 0.0 0.00062 19.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KOS19016.1 - 5.7e-05 23.2 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 KOS19016.1 - 8.8e-05 22.1 0.1 0.00019 21.0 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain phage_tail_N PF08400.5 KOS19018.1 - 0.067 12.9 0.3 0.1 12.2 0.2 1.2 1 0 0 1 1 1 0 Prophage tail fibre N-terminal DUF4072 PF13284.1 KOS19018.1 - 0.12 12.5 0.5 0.21 11.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) Atg14 PF10186.4 KOS19018.1 - 0.74 8.6 3.3 0.75 8.6 2.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HCO3_cotransp PF00955.16 KOS19019.1 - 9.8e-62 209.2 11.8 8.5e-29 100.5 0.7 3.0 2 1 1 3 3 3 3 HCO3- transporter family Peptidase_M41 PF01434.13 KOS19020.1 - 8e-76 254.2 0.0 1.2e-75 253.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KOS19020.1 - 4e-30 104.7 0.0 1.2e-29 103.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KOS19020.1 - 6.4e-11 42.4 0.0 1.8e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular TIP49 PF06068.8 KOS19020.1 - 0.0022 16.7 0.1 0.0046 15.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 KOS19020.1 - 0.003 18.3 0.0 0.021 15.6 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.9 KOS19020.1 - 0.0096 15.6 0.0 0.031 14.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KOS19020.1 - 0.0098 15.3 0.5 0.029 13.7 0.3 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS19020.1 - 0.016 14.3 0.2 0.051 12.6 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 KOS19020.1 - 0.02 14.6 1.1 0.047 13.4 0.8 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_2 PF07724.9 KOS19020.1 - 0.034 14.0 0.0 0.11 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KOS19020.1 - 0.035 13.1 0.0 0.075 12.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KOS19020.1 - 0.04 14.0 0.1 0.63 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KOS19020.1 - 0.048 13.6 0.2 0.46 10.4 0.1 2.3 1 1 1 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.12 KOS19020.1 - 0.05 13.0 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 KOS19020.1 - 0.093 12.6 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Methyltransf_26 PF13659.1 KOS19021.1 - 8.9e-15 54.7 0.0 4.9e-14 52.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS19021.1 - 8.1e-09 35.2 0.0 4.2e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS19021.1 - 1.4e-08 35.2 0.0 3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS19021.1 - 1.8e-07 30.7 0.0 5e-06 25.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.11 KOS19021.1 - 2.2e-05 23.7 0.0 3.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase PrmA PF06325.8 KOS19021.1 - 7.1e-05 22.0 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_10 PF05971.7 KOS19021.1 - 0.00016 20.9 0.0 0.00024 20.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_25 PF13649.1 KOS19021.1 - 0.00041 20.6 0.0 0.001 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KOS19021.1 - 0.00048 19.7 0.0 0.00072 19.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_32 PF13679.1 KOS19021.1 - 0.0015 18.2 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS19021.1 - 0.002 17.8 0.0 0.0057 16.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 KOS19021.1 - 0.003 17.1 0.0 0.016 14.7 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 KOS19021.1 - 0.0098 16.3 0.0 0.029 14.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS19021.1 - 0.01 16.2 0.0 0.022 15.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KOS19021.1 - 0.014 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AviRa PF11599.3 KOS19021.1 - 0.025 13.6 0.0 0.081 11.9 0.0 1.7 2 0 0 2 2 2 0 RRNA methyltransferase AviRa RNA_pol_L_2 PF13656.1 KOS19022.1 - 2.4e-22 78.1 0.0 3.1e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KOS19022.1 - 1e-08 34.1 0.0 1.4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LSM PF01423.17 KOS19023.1 - 1.9e-21 75.3 0.0 2.2e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 LSM domain DNA_pol_A_exo1 PF01612.15 KOS19024.1 - 4.6e-12 45.7 0.0 7e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DNA_pol3_alpha PF07733.7 KOS19024.1 - 0.11 10.9 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit WD40 PF00400.27 KOS19025.1 - 4.7e-34 115.0 15.5 1.3e-06 28.0 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat NLE PF08154.7 KOS19025.1 - 8.1e-21 73.8 0.1 1.3e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain AAA PF00004.24 KOS19026.1 - 3.6e-50 169.5 0.0 2.5e-43 147.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KOS19026.1 - 4.6e-05 24.2 0.0 0.00048 20.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KOS19026.1 - 0.0002 20.8 0.0 0.0011 18.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KOS19026.1 - 0.00021 20.4 0.0 0.00067 18.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 KOS19026.1 - 0.00058 18.8 0.0 0.0011 17.8 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 KOS19026.1 - 0.00084 19.4 0.1 0.0042 17.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KOS19026.1 - 0.00088 19.3 0.1 0.018 15.0 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 KOS19026.1 - 0.0013 18.2 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KOS19026.1 - 0.0039 16.9 0.0 0.018 14.8 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 KOS19026.1 - 0.0082 16.2 0.0 0.038 14.1 0.0 2.2 2 0 0 2 2 1 1 RNA helicase TIP49 PF06068.8 KOS19026.1 - 0.0087 14.8 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 KOS19026.1 - 0.019 14.1 0.1 0.047 12.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KOS19026.1 - 0.023 14.5 0.0 0.071 13.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.9 KOS19026.1 - 0.028 14.1 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 KOS19026.1 - 0.03 13.4 0.0 0.071 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_2 PF07724.9 KOS19026.1 - 0.036 13.9 0.0 0.09 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) PhoH PF02562.11 KOS19026.1 - 0.039 13.1 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 KOS19026.1 - 0.06 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KOS19026.1 - 0.069 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KOS19026.1 - 0.085 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KOS19026.1 - 0.15 11.5 0.2 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KOS19026.1 - 0.16 11.4 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain PPV_E1_C PF00519.12 KOS19026.1 - 0.32 9.5 0.0 0.51 8.9 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase SH3BGR PF04908.10 KOS19027.1 - 2.4e-07 30.6 0.1 1e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein TFIIA PF03153.8 KOS19027.1 - 0.043 13.7 15.3 0.066 13.0 10.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dicty_REP PF05086.7 KOS19027.1 - 0.096 10.4 2.7 0.13 9.9 1.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hex_IIIa PF02455.11 KOS19027.1 - 1.1 7.8 6.3 1.8 7.1 4.3 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) MAP65_ASE1 PF03999.7 KOS19027.1 - 3.2 6.2 7.5 4.5 5.7 5.2 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ATP11 PF06644.6 KOS19028.1 - 1.3e-87 293.7 0.0 1.4e-86 290.2 0.0 1.9 1 1 0 1 1 1 1 ATP11 protein PAP1 PF08601.5 KOS19028.1 - 0.0017 18.1 7.6 0.002 17.8 5.3 1.2 1 0 0 1 1 1 1 Transcription factor PAP1 DUF572 PF04502.8 KOS19028.1 - 0.0049 16.1 8.6 0.0083 15.3 6.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF572) Pol_alpha_B_N PF08418.5 KOS19028.1 - 0.026 14.0 9.8 0.041 13.4 6.8 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Macoilin PF09726.4 KOS19028.1 - 0.042 12.1 10.7 0.053 11.8 7.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Mucin PF01456.12 KOS19028.1 - 0.12 12.1 20.0 0.22 11.2 13.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SAPS PF04499.10 KOS19028.1 - 0.16 10.6 1.6 0.19 10.3 1.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Menin PF05053.8 KOS19028.1 - 0.17 9.9 6.6 0.23 9.6 4.6 1.1 1 0 0 1 1 1 0 Menin KAR9 PF08580.5 KOS19028.1 - 0.34 9.1 10.4 0.44 8.7 7.2 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DNA_pol_viral_N PF00242.12 KOS19028.1 - 0.9 8.4 12.8 1.2 8.0 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Peptidase_S64 PF08192.6 KOS19028.1 - 1.5 7.0 8.3 2 6.6 5.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF1675 PF07897.6 KOS19028.1 - 1.8 8.3 14.3 3.2 7.5 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) RAP1 PF07218.6 KOS19028.1 - 1.8 6.5 14.7 2.3 6.2 10.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Hid1 PF12722.2 KOS19028.1 - 2.4 5.7 6.5 3 5.4 4.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2217 PF10265.4 KOS19028.1 - 2.8 6.5 7.6 3.9 6.1 5.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SRP-alpha_N PF04086.8 KOS19028.1 - 4 6.7 10.8 6.3 6.1 7.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2146 PF10220.4 KOS19028.1 - 4.1 5.2 6.2 5.2 4.9 4.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Plasmodium_Vir PF05795.6 KOS19028.1 - 4.1 6.4 5.4 5.9 5.9 3.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Sec3_C PF09763.4 KOS19028.1 - 7.1 4.6 6.4 9.5 4.2 4.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Dicty_REP PF05086.7 KOS19028.1 - 7.7 4.1 7.8 10 3.7 5.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MSP1_C PF07462.6 KOS19028.1 - 8.5 4.6 6.6 13 4.0 4.6 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus AMP-binding PF00501.23 KOS19029.1 - 9e-94 314.2 0.0 1.2e-93 313.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS19029.1 - 9.8e-08 32.8 0.0 2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PGA_cap PF09587.5 KOS19029.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap MaoC_dehydratas PF01575.14 KOS19030.1 - 2.6e-07 30.0 0.1 4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain Phosphodiest PF01663.17 KOS19031.1 - 9.6e-13 48.1 0.2 1.7e-12 47.3 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KOS19031.1 - 0.00011 21.5 0.0 0.0002 20.6 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KOS19031.1 - 0.0053 16.1 0.8 0.0097 15.3 0.5 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily CMAS PF02353.15 KOS19033.1 - 1.2e-62 211.5 0.0 1.4e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KOS19033.1 - 1.7e-13 50.5 0.0 4.5e-13 49.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS19033.1 - 1e-09 38.7 0.0 1.8e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS19033.1 - 0.00015 22.0 0.0 0.0003 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS19033.1 - 0.00023 21.5 0.0 0.00049 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS19033.1 - 0.00032 21.2 0.0 0.00081 19.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS19033.1 - 0.00034 20.2 0.0 0.00055 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS19033.1 - 0.0023 17.3 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KOS19033.1 - 0.0024 17.8 0.0 0.0052 16.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KOS19033.1 - 0.0089 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.1 KOS19033.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KOS19033.1 - 0.098 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MMS19_N PF14500.1 KOS19034.1 - 2.9e-42 144.7 0.0 5e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 KOS19034.1 - 8.1e-16 57.7 0.0 3.8e-13 48.9 0.0 2.9 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal Ribosomal_S9 PF00380.14 KOS19036.1 - 6.6e-34 116.7 0.7 1.1e-33 116.0 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein S9/S16 EPL1 PF10513.4 KOS19037.1 - 1.5e-14 54.5 5.9 3.3e-09 37.1 0.0 3.5 2 1 1 3 3 3 3 Enhancer of polycomb-like EF-hand_1 PF00036.27 KOS19038.1 - 1.6e-26 89.5 13.0 4.9e-07 28.5 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KOS19038.1 - 5.6e-24 84.0 3.3 3.9e-13 49.3 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KOS19038.1 - 7.3e-21 72.1 5.8 1.6e-05 24.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KOS19038.1 - 7.4e-19 66.1 12.6 2.2e-06 26.7 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KOS19038.1 - 9e-15 54.0 13.2 2.4e-05 23.8 0.8 4.6 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KOS19038.1 - 3.2e-07 30.3 0.0 0.00019 21.4 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KOS19038.1 - 4.4e-06 26.3 8.0 0.0021 17.7 0.4 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KOS19038.1 - 0.044 13.7 0.1 1.7 8.5 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain DUF947 PF06102.7 KOS19039.1 - 5e-54 182.6 26.4 5e-54 182.6 18.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF947) ABC1 PF03109.11 KOS19040.1 - 1.1e-31 109.3 0.0 1.7e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 KOS19040.1 - 0.1 11.7 0.0 13 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain EF1G PF00647.14 KOS19041.1 - 2.6e-40 136.4 0.0 4.8e-40 135.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KOS19041.1 - 1.9e-12 47.0 0.0 4.3e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KOS19041.1 - 7.6e-11 41.7 1.7 4.2e-10 39.3 0.0 2.7 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KOS19041.1 - 1.7e-07 31.3 0.0 3.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KOS19041.1 - 2.8e-06 27.7 0.1 1.1e-05 25.8 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KOS19041.1 - 0.00092 19.3 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NIF PF03031.13 KOS19042.1 - 2.3e-17 63.1 0.0 3.1e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF3827 PF12877.2 KOS19042.1 - 1 7.3 4.8 3.2 5.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) AMPKBI PF04739.10 KOS19043.1 - 2.1e-29 101.3 0.6 2.1e-29 101.3 0.4 2.9 3 1 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interation domain DUF853 PF05872.7 KOS19043.1 - 1.1 7.5 4.5 1.8 6.8 3.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Spore_coat_CotO PF14153.1 KOS19043.1 - 3.7 6.9 15.5 8.2 5.8 10.8 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Med5 PF08689.5 KOS19043.1 - 8.3 3.9 17.9 13 3.3 12.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit Med5 Peptidase_M22 PF00814.20 KOS19044.1 - 5.8e-80 268.6 0.0 7.2e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family G-patch_2 PF12656.2 KOS19045.1 - 5.4e-22 77.4 0.3 5.4e-22 77.4 0.2 4.0 4 1 1 5 5 5 1 DExH-box splicing factor binding site PRP38_assoc PF12871.2 KOS19045.1 - 0.0058 17.1 44.7 0.0058 17.1 31.0 4.3 2 1 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term G-patch PF01585.18 KOS19045.1 - 0.02 14.6 1.5 0.23 11.3 1.0 2.7 1 1 0 1 1 1 0 G-patch domain Na_H_Exchanger PF00999.16 KOS19047.1 - 2.3e-70 237.0 41.9 2.9e-70 236.7 29.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Arf PF00025.16 KOS19048.1 - 6.8e-39 132.8 0.1 1.1e-24 86.5 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 KOS19048.1 - 6.8e-11 41.4 0.0 4.8e-06 25.5 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KOS19048.1 - 1.3e-07 30.9 0.0 1.4e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KOS19048.1 - 2.2e-07 30.4 0.0 0.0052 16.1 0.0 2.2 2 0 0 2 2 2 2 Ras family SRPRB PF09439.5 KOS19048.1 - 2.6e-07 30.0 0.0 4.4e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Miro PF08477.8 KOS19048.1 - 0.00027 21.4 0.0 0.0014 19.1 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KOS19048.1 - 0.00035 20.0 0.0 0.0011 18.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KOS19048.1 - 0.0082 16.0 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNase_PH PF01138.16 KOS19049.1 - 2.9e-25 89.1 0.0 4.1e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KOS19049.1 - 0.00026 20.8 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 KOS19050.1 - 1.9e-75 253.7 42.4 5e-74 249.1 29.4 2.0 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein NPR3 PF03666.8 KOS19050.1 - 4.3 5.7 7.3 5.8 5.3 5.1 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FGGY_C PF02782.11 KOS19051.1 - 9.4e-22 77.5 0.8 1.7e-21 76.7 0.1 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KOS19051.1 - 1.3e-18 67.2 0.0 6.6e-10 38.7 0.0 2.7 3 1 0 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.16 KOS19052.1 - 3.2e-53 180.6 0.2 3.2e-53 180.6 0.1 2.1 2 0 0 2 2 2 1 Cation efflux family Rax2 PF12768.2 KOS19052.1 - 1.4 8.0 3.9 2.7 7.1 2.7 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SIR2 PF02146.12 KOS19053.1 - 2.7e-28 98.9 0.0 4.5e-28 98.1 0.0 1.4 1 1 0 1 1 1 1 Sir2 family Daxx PF03344.10 KOS19054.1 - 0.17 10.3 4.7 0.22 9.9 3.2 1.1 1 0 0 1 1 1 0 Daxx Family Dak1 PF02733.12 KOS19055.1 - 7.9e-110 366.4 6.9 1.2e-109 365.9 4.8 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KOS19055.1 - 4.5e-43 146.9 0.0 9.8e-43 145.8 0.0 1.6 1 0 0 1 1 1 1 DAK2 domain Serglycin PF04360.7 KOS19055.1 - 0.22 11.2 1.0 0.45 10.2 0.7 1.5 1 0 0 1 1 1 0 Serglycin CVNH PF08881.5 KOS19056.1 - 2e-33 114.6 0.5 3.7e-33 113.8 0.4 1.4 1 0 0 1 1 1 1 CVNH domain LysM PF01476.15 KOS19056.1 - 1.6e-14 53.5 0.0 2.9e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 LysM domain Rick_17kDa_Anti PF05433.10 KOS19056.1 - 2.6e-05 23.8 17.7 2.6e-05 23.8 12.3 2.2 2 0 0 2 2 2 1 Glycine zipper 2TM domain DUF2076 PF09849.4 KOS19056.1 - 0.0038 17.3 17.3 0.0077 16.3 12.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) TraT PF05818.7 KOS19056.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_OmpA PF13436.1 KOS19056.1 - 0.076 12.6 17.2 0.92 9.1 12.5 2.4 2 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain ATP-synt_E PF05680.7 KOS19056.1 - 0.44 10.5 2.7 1 9.3 1.9 1.6 1 0 0 1 1 1 0 ATP synthase E chain CDC45 PF02724.9 KOS19056.1 - 7 4.5 11.7 9.8 4.0 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DCP2 PF05026.8 KOS19057.1 - 9.5e-36 121.5 1.1 1.7e-35 120.7 0.8 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KOS19057.1 - 1.4e-16 60.3 0.0 2.8e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Metallophos PF00149.23 KOS19058.1 - 0.00078 18.8 0.2 0.0027 17.1 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase CLTH PF10607.4 KOS19059.1 - 3.8e-35 120.7 0.0 5.8e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KOS19059.1 - 7.1e-05 22.4 0.8 0.00017 21.2 0.1 2.0 2 0 0 2 2 2 1 LisH DUF1674 PF07896.7 KOS19060.1 - 4.2e-17 62.0 0.4 7.1e-17 61.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) CDK2AP PF09806.4 KOS19060.1 - 1.5 9.0 9.9 2.4 8.3 6.8 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SSP160 PF06933.6 KOS19060.1 - 3.3 5.5 13.7 3.5 5.4 9.5 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF566 PF04484.7 KOS19060.1 - 3.9 6.9 17.8 4.3 6.7 12.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) RAP1 PF07218.6 KOS19060.1 - 5.8 4.8 18.9 6.3 4.7 13.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NmrA PF05368.8 KOS19061.1 - 3e-25 88.8 0.0 3.8e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KOS19061.1 - 1.3e-07 31.8 1.6 2.3e-07 31.0 1.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KOS19061.1 - 1.6e-06 27.7 0.1 0.051 12.9 0.0 2.7 2 1 1 3 3 3 2 NAD dependent epimerase/dehydratase family KR PF08659.5 KOS19061.1 - 0.0003 20.5 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KOS19061.1 - 0.0024 17.7 0.6 0.006 16.5 0.4 1.7 1 0 0 1 1 1 1 short chain dehydrogenase CAF1 PF04857.15 KOS19064.1 - 3.7e-69 232.9 0.0 6.3e-69 232.2 0.0 1.4 1 0 0 1 1 1 1 CAF1 family ribonuclease Spt20 PF12090.3 KOS19064.1 - 0.2 11.0 3.7 0.086 12.1 0.5 1.9 2 0 0 2 2 2 0 Spt20 family RskA PF10099.4 KOS19064.1 - 1.1 8.9 26.3 1.4 8.6 0.6 2.8 2 1 1 3 3 3 0 Anti-sigma-K factor rskA DUF3457 PF11939.3 KOS19064.1 - 3.9 6.9 9.1 3.4 7.1 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3457) FHIPEP PF00771.15 KOS19064.1 - 6.1 5.0 8.3 0.57 8.4 2.7 1.4 2 0 0 2 2 2 0 FHIPEP family NDUF_B12 PF08122.7 KOS19065.1 - 6.2e-17 61.0 1.2 8.7e-17 60.6 0.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family ThiF PF00899.16 KOS19066.1 - 9.4e-09 35.1 0.0 0.0024 17.7 0.0 2.2 2 0 0 2 2 2 2 ThiF family Sds3 PF08598.6 KOS19067.1 - 0.061 12.8 2.6 0.15 11.5 1.6 1.8 1 1 0 1 1 1 0 Sds3-like Ras PF00071.17 KOS19068.1 - 5.4e-58 194.9 0.1 6.3e-58 194.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS19068.1 - 3.2e-19 69.5 0.0 6.1e-19 68.6 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KOS19068.1 - 1e-14 54.1 0.0 1.2e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KOS19068.1 - 1.1e-07 31.2 0.0 1.3e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KOS19068.1 - 1.7e-07 30.8 0.0 2.4e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KOS19068.1 - 1.4e-05 24.9 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KOS19068.1 - 0.036 13.2 0.3 0.14 11.3 0.0 2.0 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KOS19068.1 - 0.057 13.5 0.1 4.9 7.3 0.0 2.5 1 1 1 2 2 2 0 AAA domain Shikimate_DH PF01488.15 KOS19068.1 - 0.081 13.0 0.0 0.2 11.7 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amidase02_C PF12123.3 KOS19068.1 - 0.13 11.8 0.0 0.81 9.3 0.0 2.1 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase AAA_16 PF13191.1 KOS19068.1 - 0.16 11.9 0.3 0.4 10.6 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain Gly_transf_sug PF04488.10 KOS19069.1 - 1.7e-10 41.1 0.2 6.7e-10 39.2 0.0 2.1 3 0 0 3 3 3 1 Glycosyltransferase sugar-binding region containing DXD motif DUF1289 PF06945.8 KOS19069.1 - 0.032 13.7 0.6 0.096 12.1 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Mur_ligase_M PF08245.7 KOS19070.1 - 0.00054 20.0 0.3 0.012 15.6 0.2 2.4 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 KOS19070.1 - 0.0038 17.2 0.0 0.018 15.0 0.0 2.1 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mitofilin PF09731.4 KOS19071.1 - 1.1e-142 476.7 14.1 1.1e-142 476.7 9.8 2.4 2 1 0 2 2 2 1 Mitochondrial inner membrane protein 4HB_MCP_1 PF12729.2 KOS19071.1 - 0.033 13.5 4.0 0.079 12.3 2.7 1.6 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Syja_N PF02383.13 KOS19072.1 - 1.1e-86 290.5 0.0 1.4e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Acyl_transf_3 PF01757.17 KOS19074.1 - 5.9e-31 107.5 27.0 7.4e-31 107.2 18.7 1.1 1 0 0 1 1 1 1 Acyltransferase family DUF21 PF01595.15 KOS19076.1 - 1.2 8.3 5.8 1.4 8.1 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF21 DUF2207 PF09972.4 KOS19076.1 - 3.3 6.1 5.0 3 6.3 3.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4407 PF14362.1 KOS19076.1 - 5.4 5.8 6.9 6 5.7 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4282 PF14110.1 KOS19076.1 - 6.5 7.0 13.2 6.5 7.0 8.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4282) tRNA-synt_1 PF00133.17 KOS19077.1 - 2.4e-145 484.8 0.0 3.8e-145 484.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KOS19077.1 - 5.7e-18 64.7 0.0 6.5e-10 38.2 0.0 3.9 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KOS19077.1 - 2e-15 56.8 0.0 3.5e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 KOS19077.1 - 4.8e-05 22.8 2.0 9.8e-05 21.8 1.4 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 KOS19077.1 - 0.026 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Methyltransf_11 PF08241.7 KOS19082.1 - 3.7e-10 40.1 0.1 1.3e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS19082.1 - 1.5e-07 31.2 0.0 2.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS19082.1 - 6.9e-07 29.8 0.0 1.6e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS19082.1 - 1.2e-06 28.9 0.0 7.1e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS19082.1 - 0.0012 18.4 0.0 0.0027 17.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS19082.1 - 0.0052 16.8 2.0 0.0061 16.5 0.2 2.0 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KOS19082.1 - 0.0059 15.7 0.0 0.011 14.8 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 KOS19082.1 - 0.084 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.15 KOS19082.1 - 0.091 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase LSM PF01423.17 KOS19083.1 - 1.3e-19 69.4 0.1 1.6e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KOS19083.1 - 0.0018 18.1 0.1 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 KOS19083.1 - 0.047 13.5 0.1 0.056 13.2 0.1 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain SPAN PF02510.9 KOS19083.1 - 0.077 12.0 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein Rad60-SLD PF11976.3 KOS19084.1 - 8.4e-14 51.0 0.1 1.5e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KOS19084.1 - 0.022 14.1 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Serglycin PF04360.7 KOS19084.1 - 0.027 14.1 0.0 0.95 9.1 0.0 2.5 2 1 0 2 2 2 0 Serglycin SIR2 PF02146.12 KOS19085.1 - 9.9e-25 87.2 0.0 3.2e-24 85.6 0.0 1.8 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 KOS19085.1 - 0.1 12.3 0.1 0.68 9.6 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Rhomboid PF01694.17 KOS19086.1 - 8.1e-19 68.0 10.6 8.1e-19 68.0 7.3 1.7 2 0 0 2 2 2 1 Rhomboid family Claudin_2 PF13903.1 KOS19086.1 - 0.0035 17.0 0.0 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction FAM75 PF14650.1 KOS19087.1 - 0.46 9.8 6.8 0.7 9.2 4.7 1.2 1 0 0 1 1 1 0 FAM75 family DUF4112 PF13430.1 KOS19088.1 - 5.5e-32 109.8 0.2 7.2e-32 109.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF1405 PF07187.6 KOS19088.1 - 0.039 13.6 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1405) Ribonuc_red_sm PF00268.16 KOS19089.1 - 7e-119 395.9 2.4 8.3e-119 395.7 1.6 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.7 KOS19090.1 - 4.4e-25 87.2 0.0 6.2e-25 86.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) TFIIA PF03153.8 KOS19090.1 - 3.2 7.5 10.2 3.8 7.3 7.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 KOS19091.1 - 6.8e-20 70.1 5.4 2.1e-10 40.0 0.4 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KOS19091.1 - 0.0045 15.7 0.1 0.26 9.9 0.1 2.2 1 1 1 2 2 2 2 Nup133 N terminal like CVNH PF08881.5 KOS19092.1 - 1.1e-15 57.7 0.0 1.3e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 CVNH domain Phage_fiber_C PF06820.7 KOS19092.1 - 0.12 12.5 0.1 0.34 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative prophage tail fibre C-terminus Mito_carr PF00153.22 KOS19094.1 - 3.5e-58 193.3 1.0 1.8e-19 69.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2392 PF10288.4 KOS19095.1 - 1.7e-15 57.2 0.0 8.7e-14 51.7 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) PH PF00169.24 KOS19096.1 - 2.3e-25 88.7 1.1 4e-13 49.4 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 KOS19096.1 - 4.2e-10 39.8 2.9 4.2e-05 23.6 0.7 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 KOS19096.1 - 4.8e-09 36.4 6.6 0.00032 20.9 0.3 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KOS19096.1 - 0.00028 20.8 0.3 0.00071 19.5 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Med2 PF11214.3 KOS19097.1 - 0.079 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 MCM PF00493.18 KOS19099.1 - 5.4e-142 472.4 0.3 7.6e-142 471.9 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KOS19099.1 - 9.4e-19 68.0 1.3 2e-18 67.0 0.4 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KOS19099.1 - 1.9e-06 27.2 0.0 0.00021 20.5 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KOS19099.1 - 8.4e-06 25.5 0.0 2.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KOS19099.1 - 0.00021 20.9 0.0 0.0011 18.6 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KOS19099.1 - 0.031 14.4 0.1 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KOS19099.1 - 0.04 13.4 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 KOS19099.1 - 0.28 11.5 4.1 0.15 12.4 0.5 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI WD40 PF00400.27 KOS19101.1 - 2.4e-69 226.9 30.2 2.5e-08 33.4 0.0 10.8 10 1 0 10 10 10 10 WD domain, G-beta repeat Utp13 PF08625.6 KOS19101.1 - 3.8e-45 152.9 0.0 6.7e-45 152.1 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.6 KOS19101.1 - 2.4e-09 36.4 2.0 0.21 10.2 0.0 5.7 6 0 0 6 6 6 3 Nup133 N terminal like Nup160 PF11715.3 KOS19101.1 - 1.6e-07 29.8 3.3 0.16 10.0 0.1 4.8 4 2 0 4 4 4 3 Nucleoporin Nup120/160 UCH PF00443.24 KOS19102.1 - 6.8e-25 87.6 0.0 9.3e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KOS19102.1 - 2.2e-11 43.6 0.3 2.2e-11 43.6 0.2 1.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein IF4E PF01652.13 KOS19103.1 - 5.7e-50 169.0 0.0 7.5e-50 168.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TIMELESS PF04821.9 KOS19104.1 - 3.8e-90 301.7 0.0 3e-89 298.8 0.0 2.5 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 KOS19104.1 - 2.7e-27 95.9 21.6 2.7e-27 95.9 15.0 4.2 2 1 1 3 3 3 1 Timeless protein C terminal region 3HCDH_N PF02737.13 KOS19105.1 - 7.4e-52 175.6 1.0 9.5e-52 175.2 0.7 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KOS19105.1 - 1.3e-33 115.2 0.0 4.2e-33 113.6 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Saccharop_dh PF03435.13 KOS19105.1 - 0.0027 16.7 0.1 0.0038 16.2 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 KOS19105.1 - 0.0045 16.8 0.2 0.014 15.2 0.1 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 KOS19105.1 - 0.039 13.9 0.4 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain DAO PF01266.19 KOS19105.1 - 0.042 12.7 0.0 0.063 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 KOS19105.1 - 0.06 13.0 0.4 0.11 12.1 0.3 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Homeobox PF00046.24 KOS19106.1 - 9.3e-18 63.6 2.8 1.6e-17 62.8 1.9 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KOS19106.1 - 0.0017 17.9 0.7 0.0061 16.2 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain Rox3 PF08633.5 KOS19107.1 - 2.3e-28 99.8 0.1 1.1e-27 97.6 0.0 1.8 2 0 0 2 2 2 1 Rox3 mediator complex subunit HEAT_2 PF13646.1 KOS19108.1 - 0.0017 18.5 10.3 0.28 11.4 0.0 6.4 6 1 1 7 7 7 1 HEAT repeats HEAT PF02985.17 KOS19108.1 - 0.0043 17.0 1.3 22 5.4 0.1 5.6 6 0 0 6 6 6 1 HEAT repeat DUF2682 PF10909.3 KOS19108.1 - 0.042 14.1 0.6 0.61 10.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2682) HEAT_EZ PF13513.1 KOS19108.1 - 2.1 8.9 10.9 1.5 9.4 0.4 5.3 6 0 0 6 6 6 0 HEAT-like repeat Pkinase PF00069.20 KOS19109.1 - 1.7e-63 214.2 0.0 2.4e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19109.1 - 2.3e-27 95.7 0.0 3e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS19109.1 - 0.0013 17.7 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KOS19109.1 - 0.055 12.5 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KOS19109.1 - 0.078 12.3 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 KOS19110.1 - 1.7e-56 191.3 0.0 2.8e-56 190.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19110.1 - 7.7e-33 113.6 0.0 7.7e-31 107.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KOS19110.1 - 1.1e-09 37.6 0.0 3.8e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KOS19110.1 - 0.0014 18.4 0.4 0.0014 18.4 0.3 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Capsule_synth PF05159.9 KOS19110.1 - 0.076 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein Pox_ser-thr_kin PF05445.6 KOS19110.1 - 0.21 10.3 0.1 0.39 9.4 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Sybindin PF04099.7 KOS19111.1 - 2.6e-22 79.0 0.0 3.7e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Pex14_N PF04695.8 KOS19111.1 - 0.0063 16.5 2.8 0.0079 16.2 1.9 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sedlin_N PF04628.8 KOS19111.1 - 0.035 13.9 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region PRCC PF10253.4 KOS19111.1 - 0.14 12.8 5.8 0.19 12.4 4.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF605 PF04652.11 KOS19111.1 - 1.1 8.6 13.8 1.3 8.3 9.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF1421 PF07223.6 KOS19111.1 - 8 6.1 29.1 11 5.6 20.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) Peroxin-3 PF04882.7 KOS19112.1 - 1.7e-136 455.3 0.0 2e-136 455.1 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DUF1649 PF07855.7 KOS19113.1 - 5.9e-62 208.1 0.0 7.1e-62 207.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Fork_head PF00250.13 KOS19114.1 - 3e-34 116.9 0.2 4.7e-34 116.2 0.1 1.2 1 0 0 1 1 1 1 Fork head domain EF-hand_4 PF12763.2 KOS19115.1 - 1.9e-26 91.8 0.0 2.1e-14 53.1 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KOS19115.1 - 0.002 18.2 0.0 0.19 11.8 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair E3_binding PF02817.12 KOS19115.1 - 0.017 14.7 0.1 0.047 13.3 0.1 1.8 1 0 0 1 1 1 0 e3 binding domain EF-hand_6 PF13405.1 KOS19115.1 - 0.025 14.4 0.2 3.2 7.8 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain AKAP7_RIRII_bdg PF10470.4 KOS19116.1 - 0.0063 16.3 0.3 0.1 12.4 0.2 2.4 2 0 0 2 2 2 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein DUF4611 PF15387.1 KOS19116.1 - 0.027 14.6 4.5 0.13 12.4 3.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.6 KOS19116.1 - 0.18 11.6 1.7 0.42 10.4 1.2 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal LRR_7 PF13504.1 KOS19116.1 - 0.26 11.6 2.9 11 6.7 0.1 4.1 5 0 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 KOS19116.1 - 4.1 7.1 4.8 54 3.5 0.1 3.4 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Nucleoplasmin PF03066.10 KOS19116.1 - 4.3 6.8 9.8 0.03 13.8 1.1 1.7 2 0 0 2 2 2 0 Nucleoplasmin PIF1 PF05970.9 KOS19119.1 - 2.7e-60 204.2 0.1 3.2e-57 194.1 0.0 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KOS19119.1 - 4.4e-17 62.3 0.0 1.1e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KOS19119.1 - 1.7e-08 34.6 0.0 3.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS19119.1 - 6.5e-07 29.0 0.2 1.5e-06 27.8 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 KOS19119.1 - 5.7e-05 23.2 0.1 0.00028 20.9 0.0 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.1 KOS19119.1 - 0.00019 21.0 0.1 0.013 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KOS19119.1 - 0.0002 20.3 0.0 0.00037 19.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Herpes_Helicase PF02689.9 KOS19119.1 - 0.00029 18.7 0.1 0.00095 17.0 0.0 1.7 2 0 0 2 2 2 1 Helicase AAA PF00004.24 KOS19119.1 - 0.00031 20.9 0.0 0.00062 19.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KOS19119.1 - 0.00042 20.3 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 KOS19119.1 - 0.0016 17.7 0.0 0.0031 16.7 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_14 PF13173.1 KOS19119.1 - 0.0039 17.0 0.0 0.014 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KOS19119.1 - 0.0039 17.4 0.0 0.0092 16.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Viral_helicase1 PF01443.13 KOS19119.1 - 0.0075 15.8 0.4 0.26 10.7 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KOS19119.1 - 0.0076 15.2 0.0 0.032 13.1 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 KOS19119.1 - 0.0086 15.5 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 KOS19119.1 - 0.011 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KOS19119.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 KOS19119.1 - 0.021 14.5 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 KOS19119.1 - 0.024 13.5 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.2 KOS19119.1 - 0.038 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 MobB PF03205.9 KOS19119.1 - 0.04 13.6 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KOS19119.1 - 0.04 13.3 0.0 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein TEX33 PF15400.1 KOS19119.1 - 0.042 14.2 0.0 0.099 13.0 0.0 1.6 1 0 0 1 1 1 0 Testis-expressed sequence 33 protein family Sigma54_activat PF00158.21 KOS19119.1 - 0.045 13.2 0.2 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 KOS19119.1 - 0.071 12.8 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 1 0 NTPase AAA_5 PF07728.9 KOS19119.1 - 0.088 12.5 0.2 0.64 9.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FokI_C PF02980.11 KOS19119.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain AAA_10 PF12846.2 KOS19119.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain TrwB_AAD_bind PF10412.4 KOS19119.1 - 0.14 10.7 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Parvo_NS1 PF01057.12 KOS19119.1 - 0.15 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF258 PF03193.11 KOS19119.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF815 PF05673.8 KOS19119.1 - 0.21 10.5 0.0 0.57 9.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.8 KOS19119.1 - 0.23 10.1 0.0 1.7 7.2 0.0 2.1 3 0 0 3 3 3 0 TIP49 C-terminus DDHD PF02862.12 KOS19120.1 - 0.25 11.0 6.4 0.064 13.0 0.3 2.2 2 0 0 2 2 2 0 DDHD domain Cullin PF00888.17 KOS19121.1 - 1.2e-105 354.2 0.0 1.9e-105 353.6 0.0 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KOS19121.1 - 2.2e-25 88.2 0.4 4.9e-25 87.1 0.3 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain EF1_GNE PF00736.14 KOS19122.1 - 2.3e-30 104.1 1.4 4e-30 103.3 1.0 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KOS19122.1 - 1.7e-14 53.6 9.0 1.7e-14 53.6 6.2 2.6 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KOS19122.1 - 0.00064 20.1 0.0 0.0017 18.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KOS19122.1 - 0.00065 19.6 0.0 0.0024 17.8 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.7 KOS19122.1 - 0.05 13.2 1.5 0.075 12.7 1.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MRP-S26 PF14943.1 KOS19122.1 - 0.054 13.0 0.4 0.23 11.0 0.2 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 ABC_tran PF00005.22 KOS19123.1 - 2.6e-33 115.2 0.0 4.7e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KOS19123.1 - 2.3e-17 63.2 3.5 2.3e-17 63.2 2.5 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region DUF258 PF03193.11 KOS19123.1 - 0.0074 15.4 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KOS19123.1 - 0.011 15.2 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KOS19123.1 - 0.018 15.2 0.1 0.068 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 KOS19123.1 - 0.022 14.7 0.0 7.9 6.3 0.0 2.5 1 1 1 2 2 2 0 AAA domain SMC_N PF02463.14 KOS19123.1 - 0.035 13.3 0.0 0.12 11.6 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KOS19123.1 - 0.039 13.8 0.1 0.45 10.4 0.1 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KOS19123.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TRAM_LAG1_CLN8 PF03798.11 KOS19124.1 - 2.2e-35 122.0 16.4 2.2e-35 122.0 11.4 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KOS19124.1 - 2.7e-25 87.6 0.0 6.1e-25 86.5 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein Daxx PF03344.10 KOS19124.1 - 2 6.8 4.4 3.2 6.1 3.0 1.2 1 0 0 1 1 1 0 Daxx Family PalH PF08733.5 KOS19125.1 - 1.3e-97 326.8 0.0 1.6e-97 326.4 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 TFIIA PF03153.8 KOS19125.1 - 0.53 10.1 9.1 1.5 8.6 6.4 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 KOS19125.1 - 0.59 9.8 2.7 1.1 8.8 1.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 KOS19125.1 - 1 8.8 7.1 0.031 13.7 0.6 1.6 2 0 0 2 2 2 0 Nucleoplasmin Nop14 PF04147.7 KOS19125.1 - 2.3 6.0 5.5 3.3 5.5 3.8 1.1 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 KOS19125.1 - 2.4 8.5 12.1 0.24 11.7 3.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 KOS19125.1 - 3.4 5.5 6.5 5 5.0 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 KOS19125.1 - 4.8 6.7 5.8 12 5.4 4.0 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4611 PF15387.1 KOS19125.1 - 6.4 7.0 13.3 0.043 13.9 3.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) YjeF_N PF03853.10 KOS19126.1 - 7.9e-36 123.2 0.0 1.3e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 KOS19126.1 - 3.2e-09 37.2 0.2 3.2e-09 37.2 0.1 2.2 2 0 0 2 2 2 1 FDF domain LEAP-2 PF07359.6 KOS19127.1 - 0.1 12.2 0.5 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Sod_Fe_C PF02777.13 KOS19128.1 - 2.2e-39 133.5 0.1 3.7e-39 132.8 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KOS19128.1 - 3.9e-29 100.7 0.4 6.4e-29 100.0 0.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain JmjC PF02373.17 KOS19129.1 - 1.5e-21 76.7 0.0 4.8e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase DUF4448 PF14610.1 KOS19130.1 - 5.6e-30 104.2 0.0 7.5e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TFIIA PF03153.8 KOS19131.1 - 0.037 13.9 11.9 0.047 13.5 8.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3716 PF12511.3 KOS19132.1 - 1.3e-07 31.0 4.9 2.3e-07 30.3 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) NAD_binding_1 PF00175.16 KOS19133.1 - 1.2e-29 103.0 0.0 1.7e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KOS19133.1 - 3e-22 78.5 0.0 9.4e-22 77.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KOS19133.1 - 1.4e-09 38.0 0.0 0.00013 21.8 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KOS19133.1 - 0.0069 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain SH3_9 PF14604.1 KOS19134.1 - 2.5e-09 36.5 0.9 5e-09 35.5 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KOS19134.1 - 4.2e-09 35.6 0.0 1e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KOS19134.1 - 1.4e-05 24.4 0.0 3.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ssu72 PF04722.8 KOS19135.1 - 1.6e-85 285.4 0.0 1.8e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein GIT_SHD PF08518.6 KOS19136.1 - 9.6e-22 76.0 1.0 1.2e-13 50.1 0.6 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT SPX PF03105.14 KOS19136.1 - 0.00058 19.7 3.3 0.0009 19.1 2.3 1.3 1 0 0 1 1 1 1 SPX domain AAA_13 PF13166.1 KOS19136.1 - 0.21 10.0 14.3 0.35 9.2 9.9 1.3 1 0 0 1 1 1 0 AAA domain DUF4559 PF15112.1 KOS19136.1 - 0.96 8.5 10.8 1.9 7.5 7.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Cor1 PF04803.7 KOS19136.1 - 1.8 8.3 21.7 1.4 8.6 7.9 3.0 3 1 0 3 3 3 0 Cor1/Xlr/Xmr conserved region CENP-K PF11802.3 KOS19136.1 - 2.9 7.0 16.6 11 5.0 11.5 2.0 1 1 0 1 1 1 0 Centromere-associated protein K ODV-E18 PF10717.4 KOS19138.1 - 0.21 11.0 5.1 0.58 9.6 3.6 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DSBA PF01323.15 KOS19139.1 - 0.11 12.0 0.2 0.12 11.9 0.2 1.0 1 0 0 1 1 1 0 DSBA-like thioredoxin domain GWT1 PF06423.7 KOS19141.1 - 2.3e-43 147.5 1.7 6.5e-43 146.0 1.2 1.8 1 0 0 1 1 1 1 GWT1 Glyco_tranf_2_3 PF13641.1 KOS19143.1 - 1.1e-19 71.1 0.0 1.5e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KOS19143.1 - 8.1e-09 34.9 0.0 1.9e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KOS19143.1 - 3.7e-07 29.9 0.0 8.6e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 FAD-oxidase_C PF02913.14 KOS19144.1 - 2.8e-61 206.9 0.3 2.8e-61 206.9 0.2 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KOS19144.1 - 2e-37 127.7 0.0 3.9e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Clr5 PF14420.1 KOS19145.1 - 2.7e-16 59.2 0.1 5.6e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Clr5 domain HTH_33 PF13592.1 KOS19145.1 - 0.054 13.0 0.1 0.68 9.5 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix MFS_1 PF07690.11 KOS19146.1 - 1.6e-48 165.2 58.8 5e-47 160.3 40.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KOS19146.1 - 1.7e-24 85.9 26.3 2e-24 85.7 17.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KOS19146.1 - 7.3e-16 57.7 4.3 7.3e-16 57.7 2.9 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter Pex14_N PF04695.8 KOS19146.1 - 0.0015 18.5 3.8 0.0015 18.5 2.7 2.0 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CBP4 PF07960.6 KOS19146.1 - 0.0037 16.8 2.3 5.7 6.5 0.0 3.6 3 0 0 3 3 3 1 CBP4 RP-C_C PF11800.3 KOS19146.1 - 0.026 14.2 0.4 0.051 13.2 0.3 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region NPR3 PF03666.8 KOS19146.1 - 0.095 11.2 2.1 0.15 10.5 1.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Spt20 PF12090.3 KOS19146.1 - 0.15 11.4 4.1 0.25 10.6 2.8 1.2 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 KOS19146.1 - 0.36 10.5 4.3 0.55 9.8 3.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF912 PF06024.7 KOS19146.1 - 0.39 10.7 0.1 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pneumo_att_G PF05539.6 KOS19146.1 - 2.4 7.4 10.5 5.3 6.3 7.2 1.5 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G PHD_3 PF13922.1 KOS19146.1 - 2.8 8.2 7.7 14 6.0 3.3 2.6 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx DUF4661 PF15576.1 KOS19146.1 - 3.1 7.3 4.9 5.3 6.6 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) UPF0183 PF03676.9 KOS19147.1 - 9.1e-38 129.8 0.0 1.5e-13 50.0 0.0 5.2 5 0 0 5 5 5 5 Uncharacterised protein family (UPF0183) DEC-1_N PF04625.8 KOS19147.1 - 7.7 5.0 9.2 14 4.2 6.4 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SbcCD_C PF13558.1 KOS19148.1 - 3.3e-11 42.9 0.0 1.7e-10 40.6 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 KOS19148.1 - 2.4e-08 33.4 0.0 6.1e-06 25.5 0.0 5.3 4 2 0 5 5 5 2 AAA ATPase domain AAA_23 PF13476.1 KOS19148.1 - 2.7e-08 34.3 61.0 2.7e-08 34.3 42.3 7.7 1 1 1 3 3 3 1 AAA domain AAA_21 PF13304.1 KOS19148.1 - 1.4e-07 31.7 9.0 0.00014 21.9 0.0 3.7 5 1 0 5 5 5 2 AAA domain AAA_13 PF13166.1 KOS19148.1 - 2.1e-07 29.8 105.3 0.0042 15.6 0.0 6.8 3 2 2 5 5 5 2 AAA domain SMC_N PF02463.14 KOS19148.1 - 0.00083 18.6 51.6 0.007 15.6 35.8 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KOS19148.1 - 0.0028 17.1 0.0 0.0063 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KOS19148.1 - 0.06 13.6 0.2 0.06 13.6 0.1 7.2 3 2 1 5 5 5 0 ABC transporter AAA_19 PF13245.1 KOS19148.1 - 0.068 12.9 0.6 0.25 11.1 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain DUF948 PF06103.6 KOS19148.1 - 1.4 8.8 30.2 0.24 11.2 1.2 7.3 5 3 2 8 8 8 0 Bacterial protein of unknown function (DUF948) Kinesin PF00225.18 KOS19149.1 - 1.7e-110 368.8 0.8 3.3e-110 367.9 0.6 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 KOS19149.1 - 2.2e-05 24.6 2.0 2.2e-05 24.6 1.4 4.6 2 1 2 4 4 4 1 Kinesin-associated microtubule-binding DUF479 PF04336.7 KOS19149.1 - 0.37 10.9 2.9 1.9 8.6 0.5 3.5 2 1 1 3 3 3 0 Protein of unknown function, DUF479 ApoLp-III PF07464.6 KOS19149.1 - 2.6 8.0 30.4 1.4 8.9 5.3 4.8 2 1 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Asp PF00026.18 KOS19150.1 - 3.4e-37 128.3 0.0 6.6e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KOS19150.1 - 3.6e-05 23.3 0.1 0.0051 16.3 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KOS19150.1 - 0.00015 22.2 0.0 1.9 9.0 0.0 3.3 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 KOS19150.1 - 0.013 15.2 0.0 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Vps39_1 PF10366.4 KOS19151.1 - 2.8e-33 114.1 0.0 3.3e-32 110.7 0.0 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KOS19151.1 - 2.1e-24 85.7 0.0 1.3e-23 83.2 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 KOS19151.1 - 4.3e-19 68.9 0.0 1.3e-18 67.4 0.0 1.7 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 KOS19151.1 - 0.019 14.5 2.6 0.098 12.2 0.2 2.8 3 0 0 3 3 3 0 Region in Clathrin and VPS Cnd1_N PF12922.2 KOS19151.1 - 0.029 14.0 0.1 0.029 14.0 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term SPX PF03105.14 KOS19152.1 - 7.6e-45 153.8 0.0 1.3e-44 153.0 0.0 1.4 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 KOS19152.1 - 2.5e-33 115.7 39.7 3.7e-33 115.1 27.5 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KOS19152.1 - 3.6e-13 48.8 42.6 4e-13 48.6 15.6 2.3 1 1 1 2 2 2 2 Citrate transporter RINGv PF12906.2 KOS19153.1 - 5.5e-10 39.1 3.3 1e-08 35.0 0.9 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 KOS19153.1 - 0.0013 18.5 2.8 0.0064 16.2 0.6 2.1 2 0 0 2 2 2 1 Ring finger domain DUF202 PF02656.10 KOS19153.1 - 0.026 14.7 2.1 0.88 9.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) zf-MIZ PF02891.15 KOS19153.1 - 0.16 11.5 2.3 0.29 10.6 1.6 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger TrbL PF04610.9 KOS19153.1 - 0.18 11.5 6.5 0.37 10.4 1.0 2.1 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein HAMP PF00672.20 KOS19153.1 - 0.37 11.0 4.5 0.78 9.9 0.1 2.6 2 0 0 2 2 2 0 HAMP domain ATPase_gene1 PF09527.5 KOS19153.1 - 0.66 9.8 6.6 2.5 7.9 0.8 2.8 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) PHD PF00628.24 KOS19153.1 - 1.1 8.9 6.1 0.19 11.4 1.4 1.7 2 0 0 2 2 2 0 PHD-finger Glyco_transf_34 PF05637.7 KOS19154.1 - 9e-68 228.3 0.0 1.1e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 KOS19154.1 - 1.3e-05 24.6 0.0 0.038 13.3 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function, DUF273 RskA PF10099.4 KOS19154.1 - 0.045 13.4 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4131 PF13567.1 KOS19154.1 - 0.059 12.7 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Proteasome PF00227.21 KOS19155.1 - 1.3e-54 184.4 0.1 3e-32 111.4 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KOS19155.1 - 1.8e-11 43.0 0.3 4.2e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ribonuclease_3 PF00636.21 KOS19156.1 - 3.1e-39 133.9 0.0 5.8e-19 68.6 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KOS19156.1 - 3.3e-25 88.4 0.0 1.7e-10 40.9 0.0 4.1 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 KOS19156.1 - 6.7e-18 64.2 0.1 1.4e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 KOS19156.1 - 1.5e-14 53.5 0.0 3.8e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS19156.1 - 8.5e-08 31.8 0.0 1.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 KOS19156.1 - 0.00044 19.7 0.0 0.00097 18.5 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 KOS19156.1 - 0.0062 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 KOS19156.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif PTH2 PF01981.11 KOS19157.1 - 1.1e-49 166.9 0.3 1.5e-49 166.5 0.2 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 CHD5 PF04420.9 KOS19158.1 - 8.3e-58 194.5 0.4 8.3e-58 194.5 0.3 1.6 2 0 0 2 2 2 1 CHD5-like protein NAD_binding_9 PF13454.1 KOS19158.1 - 0.039 13.7 0.2 0.07 12.9 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF663 PF04950.7 KOS19159.1 - 1e-99 333.2 0.0 1.5e-99 332.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KOS19159.1 - 1.5e-19 69.2 0.0 3.8e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain PLRV_ORF5 PF01690.12 KOS19160.1 - 4.4 6.3 25.2 5 6.1 17.4 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CAF-1_p150 PF11600.3 KOS19160.1 - 4.5 6.5 75.8 6.6 6.0 52.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal WD40 PF00400.27 KOS19161.1 - 2.5e-09 36.6 9.3 0.0014 18.4 0.2 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 KOS19161.1 - 1.7e-05 24.6 0.2 0.2 11.3 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 KOS19161.1 - 0.047 13.1 0.8 0.18 11.1 0.6 2.1 1 1 1 2 2 2 0 PQQ-like domain DUF1708 PF08101.6 KOS19162.1 - 1.6e-147 491.7 0.0 2.9e-147 490.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF726 PF05277.7 KOS19163.1 - 5.8e-104 347.6 0.3 7.2e-104 347.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 KOS19163.1 - 0.00061 19.5 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KOS19163.1 - 0.0029 17.8 0.0 0.0055 16.9 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KOS19163.1 - 0.0037 17.1 0.4 0.0069 16.2 0.2 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.17 KOS19163.1 - 0.0068 16.1 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KOS19163.1 - 0.0072 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 KOS19163.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold IMS_C PF11799.3 KOS19163.1 - 0.08 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain Sel1 PF08238.7 KOS19164.1 - 7.6e-41 137.6 47.6 1.1e-05 25.9 0.2 13.3 12 1 1 13 13 13 8 Sel1 repeat TPR_11 PF13414.1 KOS19164.1 - 0.0002 20.9 0.1 0.0002 20.9 0.1 6.4 7 0 0 7 7 7 2 TPR repeat RAB3GAP2_N PF14655.1 KOS19164.1 - 0.13 11.2 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SNAP PF14938.1 KOS19164.1 - 1.3 8.1 6.6 3.4 6.7 0.1 2.8 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 KOS19164.1 - 3.6 8.2 25.1 6.1 7.5 0.1 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat UDG PF03167.14 KOS19165.1 - 2.3e-24 85.6 0.0 3.4e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily BSP_II PF05432.6 KOS19165.1 - 0.27 10.4 18.5 0.45 9.7 12.8 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) tRNA-synt_2c PF01411.14 KOS19166.1 - 1.5e-213 710.0 0.4 3e-213 709.1 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KOS19166.1 - 1.3e-16 60.1 0.1 3.6e-16 58.7 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KOS19166.1 - 0.012 15.2 0.2 0.049 13.3 0.1 2.1 1 0 0 1 1 1 0 DHHA1 domain Ribosomal_60s PF00428.14 KOS19167.1 - 0.0075 16.6 5.2 1 9.7 0.3 2.2 2 0 0 2 2 2 2 60s Acidic ribosomal protein PALP PF00291.20 KOS19168.1 - 2.9e-51 174.5 1.7 4e-51 174.0 1.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.12 KOS19169.1 - 1.5e-35 122.8 0.0 3.3e-35 121.6 0.0 1.5 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 KOS19169.1 - 0.032 13.1 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase LSM PF01423.17 KOS19171.1 - 7.6e-13 47.8 0.0 1.1e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain IU_nuc_hydro PF01156.14 KOS19172.1 - 5.9e-59 199.8 0.0 5.4e-46 157.2 0.0 2.0 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase DUF2183 PF09949.4 KOS19173.1 - 1.2e-32 111.8 0.0 2.5e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 KOS19173.1 - 0.095 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) WD40 PF00400.27 KOS19174.1 - 3.1e-55 182.1 17.4 8.6e-10 38.1 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KOS19174.1 - 2.1e-12 46.5 1.3 5.3e-12 45.2 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS19174.1 - 6.3e-10 38.4 0.4 1.6e-09 37.1 0.3 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KOS19174.1 - 2.6e-09 35.7 5.9 0.043 11.9 0.1 4.2 2 1 2 4 4 4 4 Nucleoporin Nup120/160 PRANC PF09372.5 KOS19174.1 - 0.081 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 PRANC domain YmzC PF14157.1 KOS19174.1 - 0.082 12.7 0.0 53 3.7 0.0 3.5 3 0 0 3 3 3 0 YmzC-like protein Dynactin_p62 PF05502.8 KOS19175.1 - 3.7e-155 517.3 0.0 4.7e-155 517.0 0.0 1.1 1 0 0 1 1 1 1 Dynactin p62 family DUF4519 PF15012.1 KOS19175.1 - 0.1 12.5 0.6 0.21 11.5 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) EBP PF05241.7 KOS19177.1 - 7.1e-05 21.9 1.8 7.1e-05 21.9 1.2 1.7 1 1 0 2 2 2 1 Emopamil binding protein CAP_N PF01213.14 KOS19177.1 - 0.3 10.3 4.6 0.46 9.7 3.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Bacteriocin_IId PF09221.5 KOS19177.1 - 3.8 7.5 7.3 1.4 8.9 0.9 2.3 1 1 1 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like Mito_carr PF00153.22 KOS19179.1 - 7.6e-67 221.0 0.2 1.8e-21 75.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WSC PF01822.14 KOS19180.1 - 0.051 13.4 4.8 0.072 13.0 2.6 1.8 1 1 0 1 1 1 0 WSC domain Ribosomal_S7e PF01251.13 KOS19181.1 - 2.8e-83 278.0 0.8 3.2e-83 277.9 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Thioredoxin PF00085.15 KOS19182.1 - 2.6e-58 194.1 0.0 1.8e-29 101.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 KOS19182.1 - 3.2e-21 75.7 0.1 2.1e-20 73.1 0.0 2.3 3 0 0 3 3 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 KOS19182.1 - 9.2e-17 61.2 0.0 1.6e-07 31.5 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KOS19182.1 - 3.8e-13 49.3 0.0 1.4e-05 25.1 0.0 3.0 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KOS19182.1 - 1.1e-11 44.5 0.0 0.00022 21.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 KOS19182.1 - 3.9e-09 36.2 0.0 0.0022 17.6 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 KOS19182.1 - 8.5e-09 35.0 0.0 0.00019 21.0 0.0 2.3 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.8 KOS19182.1 - 7.6e-05 22.6 0.0 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_9 PF14595.1 KOS19182.1 - 0.00015 21.3 0.0 0.14 11.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_4 PF13462.1 KOS19182.1 - 0.0002 21.4 0.8 2.5 8.1 0.0 4.2 3 2 1 4 4 4 2 Thioredoxin Glutaredoxin PF00462.19 KOS19182.1 - 0.00084 19.2 0.0 0.8 9.7 0.0 2.7 2 0 0 2 2 2 2 Glutaredoxin HyaE PF07449.6 KOS19182.1 - 0.012 15.5 0.0 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE TraF PF13728.1 KOS19182.1 - 0.073 12.5 0.0 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Ribosomal_S14 PF00253.16 KOS19183.1 - 4.6e-17 61.1 3.5 5.9e-17 60.7 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 KOS19183.1 - 0.16 11.7 1.5 0.22 11.3 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) ZZ PF00569.12 KOS19183.1 - 0.39 10.3 4.0 3.4 7.2 2.8 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type zf-rbx1 PF12678.2 KOS19185.1 - 4.9e-09 36.1 0.6 4.9e-09 36.1 0.4 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KOS19185.1 - 4.1e-08 32.9 7.3 1.5e-07 31.1 5.1 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KOS19185.1 - 6.2e-07 29.0 0.8 1.4e-06 27.8 0.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KOS19185.1 - 3.3e-06 26.6 1.0 3.3e-06 26.6 0.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS19185.1 - 4.8e-05 22.9 3.9 0.00016 21.2 2.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS19185.1 - 0.0004 20.3 2.4 0.0004 20.3 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KOS19185.1 - 0.0043 16.8 1.3 0.019 14.7 0.3 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KOS19185.1 - 0.072 12.8 3.9 0.14 11.9 1.5 2.3 1 1 0 1 1 1 0 RING-type zinc-finger DUF2921 PF11145.3 KOS19185.1 - 0.18 9.5 0.1 0.25 8.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) DNA_pol_B PF00136.16 KOS19186.1 - 2.5e-145 484.8 0.6 3.5e-145 484.3 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KOS19186.1 - 3.9e-81 272.4 0.0 9.3e-81 271.1 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain Rhomboid PF01694.17 KOS19186.1 - 2.5e-33 115.1 8.0 2.5e-33 115.1 5.6 2.5 3 0 0 3 3 3 1 Rhomboid family zf-C4pol PF14260.1 KOS19186.1 - 1e-22 79.8 4.6 2.7e-22 78.5 3.2 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KOS19186.1 - 0.00046 20.0 0.1 0.0019 18.0 0.1 2.1 1 1 0 1 1 1 1 RNase_H superfamily DUF2614 PF11023.3 KOS19186.1 - 0.01 15.6 0.0 0.046 13.5 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) DNA_pol_B_exo2 PF10108.4 KOS19186.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB ELFV_dehydrog PF00208.16 KOS19189.1 - 2.4e-83 279.4 0.3 3e-83 279.1 0.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KOS19189.1 - 1.1e-45 154.3 0.0 1.9e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 KOS19189.1 - 0.0029 17.8 0.0 0.0082 16.3 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding WD40 PF00400.27 KOS19190.1 - 8.7e-25 85.6 15.2 2.4e-07 30.3 0.3 7.7 7 0 0 7 7 7 4 WD domain, G-beta repeat CLTH PF10607.4 KOS19190.1 - 0.0027 17.4 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain BBS2_Mid PF14783.1 KOS19190.1 - 0.0051 16.5 0.0 0.049 13.4 0.0 2.6 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region DUF4221 PF13970.1 KOS19190.1 - 0.0054 16.0 0.0 1.9 7.7 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4221) Dynamin_M PF01031.15 KOS19191.1 - 7e-105 350.0 0.2 2.4e-104 348.2 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KOS19191.1 - 1.6e-55 187.5 0.0 2.9e-55 186.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KOS19191.1 - 1.9e-29 101.3 4.4 1.9e-29 101.3 3.1 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KOS19191.1 - 0.00011 22.1 0.2 0.0017 18.2 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KOS19191.1 - 0.0093 16.4 0.0 0.042 14.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein SpoIIE PF07228.7 KOS19192.1 - 2.4e-07 30.6 0.0 1.5e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KOS19192.1 - 9.8e-07 28.3 0.0 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KOS19192.1 - 0.00058 19.3 0.1 0.32 10.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C DUF106 PF01956.11 KOS19193.1 - 1.7e-55 187.1 2.6 2.4e-55 186.6 1.8 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 Cytochrom_B_N PF00033.14 KOS19193.1 - 0.025 13.9 0.9 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB TPPK_C PF12555.3 KOS19193.1 - 0.22 11.2 0.9 0.44 10.3 0.6 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal RNA_pol_Rbc25 PF08292.7 KOS19194.1 - 9.5e-34 116.2 0.1 1.3e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KOS19194.1 - 9.8e-14 51.2 0.1 1.6e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DNA_pol_B PF00136.16 KOS19195.1 - 3.9e-109 365.5 0.5 6.1e-109 364.8 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KOS19195.1 - 6e-65 218.1 0.1 1.3e-64 217.0 0.1 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KOS19195.1 - 3.6e-39 134.5 0.0 6.1e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KOS19195.1 - 4.1e-23 80.9 9.8 4.1e-23 80.9 6.8 3.0 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal NUFIP1 PF10453.4 KOS19196.1 - 7.3e-11 41.3 1.3 7.3e-11 41.3 0.9 2.6 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) SPX PF03105.14 KOS19196.1 - 0.046 13.5 5.4 0.1 12.3 3.7 1.6 1 1 0 1 1 1 0 SPX domain zf-CCCH PF00642.19 KOS19196.1 - 0.066 12.9 6.1 0.13 12.0 4.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2514 PF10721.4 KOS19196.1 - 1.1 8.9 18.1 0.032 13.9 5.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2514) Peptidase_M3_N PF08439.5 KOS19196.1 - 2.1 8.4 5.8 3.3 7.8 0.1 2.9 3 0 0 3 3 3 0 Oligopeptidase F SPC25 PF06703.6 KOS19197.1 - 3e-50 169.9 0.0 3.5e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Big_3_4 PF13754.1 KOS19197.1 - 0.0025 18.0 0.2 0.0049 17.1 0.1 1.5 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) ALF PF03752.8 KOS19197.1 - 0.11 12.3 0.1 0.65 9.8 0.1 2.3 2 0 0 2 2 2 0 Short repeats of unknown function DUF308 PF03729.8 KOS19197.1 - 0.23 11.4 3.6 0.5 10.4 2.5 1.5 1 1 0 1 1 1 0 Short repeat of unknown function (DUF308) WD40 PF00400.27 KOS19198.1 - 4.3e-09 35.9 1.7 0.002 17.9 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat RNA_pol_N PF01194.12 KOS19199.1 - 1.1e-28 99.0 1.0 1.3e-28 98.7 0.7 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 KOS19199.1 - 0.05 13.7 0.2 0.08 13.0 0.1 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Mqo PF06039.10 KOS19199.1 - 0.082 11.0 0.0 0.099 10.8 0.0 1.0 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) RRM_1 PF00076.17 KOS19200.1 - 2.7e-43 145.4 0.1 1.2e-15 56.8 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS19200.1 - 6e-36 122.2 0.1 4.9e-13 48.8 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS19200.1 - 6.8e-17 61.0 0.0 1.2e-06 28.2 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KOS19200.1 - 2.1e-05 24.1 0.3 4.5 7.1 0.0 3.8 3 0 0 3 3 3 3 Limkain b1 RRM_3 PF08777.6 KOS19200.1 - 0.041 13.7 2.0 3.2 7.6 0.0 3.5 2 1 1 3 3 3 0 RNA binding motif DUF221 PF02714.10 KOS19200.1 - 0.2 10.5 0.0 0.38 9.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF221 TEA PF01285.13 KOS19201.1 - 1.7e-15 57.1 2.8 3.6e-12 46.1 0.0 2.9 3 0 0 3 3 3 2 TEA/ATTS domain family Ribosomal_60s PF00428.14 KOS19201.1 - 5.2 7.5 17.6 4.1 7.8 2.8 3.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF2796 PF10986.3 KOS19202.1 - 0.005 16.8 12.3 0.0085 16.0 8.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2796) Macoilin PF09726.4 KOS19202.1 - 0.15 10.2 4.4 0.21 9.8 3.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Tom22 PF04281.8 KOS19202.1 - 0.2 11.1 1.5 0.38 10.2 1.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Zip PF02535.17 KOS19202.1 - 0.21 10.5 4.8 0.34 9.8 3.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter fn3 PF00041.16 KOS19203.1 - 2.1e-10 40.5 0.1 6.5e-10 39.0 0.1 1.9 1 0 0 1 1 1 1 Fibronectin type III domain TBPIP PF07106.8 KOS19203.1 - 0.0017 17.8 12.7 0.0017 17.8 8.8 2.4 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-B_dimeris PF09026.5 KOS19204.1 - 0.16 12.2 10.3 0.43 10.8 7.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 KOS19204.1 - 0.47 10.2 4.6 1.2 8.8 3.2 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.7 KOS19204.1 - 4.6 5.0 10.4 7 4.4 7.2 1.3 1 0 0 1 1 1 0 Nop14-like family EF1G PF00647.14 KOS19205.1 - 0.0062 16.2 0.7 0.31 10.7 0.2 2.3 2 0 0 2 2 2 2 Elongation factor 1 gamma, conserved domain Dynein_light PF01221.13 KOS19206.1 - 2.7e-29 100.9 5.3 1.2e-28 98.9 3.6 1.8 1 1 0 1 1 1 1 Dynein light chain type 1 Imm28 PF15574.1 KOS19206.1 - 0.023 14.2 0.1 0.087 12.3 0.0 1.6 1 1 1 2 2 2 0 Immunity protein 28 RRM_6 PF14259.1 KOS19207.1 - 6.1e-12 45.3 0.0 7.2e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS19207.1 - 3.3e-11 42.6 0.0 3.9e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS19207.1 - 0.00044 20.0 0.0 0.00062 19.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KOS19207.1 - 0.043 13.5 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sel1 PF08238.7 KOS19207.1 - 0.088 13.4 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 Sel1 repeat DUF2347 PF09804.4 KOS19208.1 - 6.7e-91 304.4 0.0 2.7e-90 302.4 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 KOS19208.1 - 1.6e-46 158.6 0.0 2.3e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 KOS19208.1 - 0.00018 21.1 0.0 0.00059 19.5 0.0 1.7 1 1 0 1 1 1 1 Stabilization of polarity axis Acyltransferase PF01553.16 KOS19209.1 - 2.6e-32 111.0 0.0 4.2e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acetyltransf_1 PF00583.19 KOS19210.1 - 0.0022 18.0 0.1 0.0049 16.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS19210.1 - 0.0074 16.4 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS19210.1 - 0.0081 16.0 0.0 0.049 13.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Mtc PF03820.12 KOS19211.1 - 1.8e-97 325.7 0.0 4.9e-75 252.0 0.0 2.1 2 0 0 2 2 2 2 Tricarboxylate carrier DUF4045 PF13254.1 KOS19212.1 - 5.6e-64 216.9 34.8 3.3e-35 122.1 13.7 5.4 3 3 3 6 6 6 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 KOS19212.1 - 1.3e-09 37.5 0.2 0.00041 19.9 0.0 3.7 3 0 0 3 3 3 3 Gelsolin repeat Arf PF00025.16 KOS19213.1 - 9.7e-54 181.2 0.9 1.6e-53 180.4 0.6 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KOS19213.1 - 4e-05 23.5 0.2 0.0011 18.9 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KOS19213.1 - 0.00017 20.4 0.5 0.0014 17.3 0.0 2.0 1 1 0 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 KOS19213.1 - 0.0004 19.8 0.1 0.045 13.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KOS19213.1 - 0.00062 19.0 0.1 0.021 14.0 0.1 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KOS19213.1 - 0.00091 19.7 0.1 0.0038 17.7 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KOS19213.1 - 0.0021 17.2 0.1 0.16 11.0 0.1 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KOS19213.1 - 0.041 13.3 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 KOS19213.1 - 0.11 12.1 0.9 0.83 9.2 0.0 2.0 1 1 0 2 2 2 0 NACHT domain 6PF2K PF01591.13 KOS19213.1 - 0.14 11.2 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Dynamin_N PF00350.18 KOS19213.1 - 0.15 11.8 0.0 0.44 10.3 0.0 1.7 2 0 0 2 2 2 0 Dynamin family AMP-binding PF00501.23 KOS19214.1 - 2.6e-62 210.5 0.0 1.8e-36 125.4 0.0 4.1 3 2 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.6 KOS19214.1 - 8.3e-10 39.2 0.0 2.2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 KOS19214.1 - 0.00073 19.3 0.4 0.0016 18.1 0.2 1.5 1 0 0 1 1 1 1 Gas vesicle protein G Pkinase PF00069.20 KOS19216.1 - 4.2e-58 196.5 0.0 6.2e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19216.1 - 3.5e-18 65.6 0.0 2.6e-17 62.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KOS19216.1 - 0.042 12.6 0.2 0.063 12.0 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3701 PF12482.3 KOS19217.1 - 0.026 14.2 1.2 0.045 13.4 0.2 1.8 2 0 0 2 2 2 0 Phage integrase protein HEAT_2 PF13646.1 KOS19218.1 - 1.3e-16 60.6 1.5 0.0021 18.3 0.0 6.6 6 0 0 6 6 6 4 HEAT repeats HEAT PF02985.17 KOS19218.1 - 1e-08 34.5 12.9 0.31 11.2 0.0 9.3 9 0 0 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KOS19218.1 - 8e-08 32.5 0.1 0.04 14.3 0.0 4.2 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KOS19218.1 - 0.00031 20.1 0.7 1.1 8.5 0.0 4.7 4 1 0 4 4 4 1 CLASP N terminal Transcrip_reg PF01709.15 KOS19219.1 - 1.6e-43 148.5 0.0 2e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator zf-CHCC PF10276.4 KOS19220.1 - 2e-13 49.9 0.7 2.9e-13 49.4 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 KOS19220.1 - 0.016 14.8 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb Amidase_5 PF05382.8 KOS19220.1 - 0.068 12.7 0.1 0.097 12.2 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase SR-25 PF10500.4 KOS19221.1 - 0.015 14.7 4.2 0.021 14.3 2.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_M16 PF00675.15 KOS19222.1 - 1.5e-33 115.6 0.1 6.5e-32 110.3 0.1 3.0 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KOS19222.1 - 1.1e-28 100.2 0.0 2.4e-16 59.9 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain UCH PF00443.24 KOS19223.1 - 3.9e-75 252.4 0.0 1.3e-74 250.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS19223.1 - 4.2e-16 59.2 0.0 3.2e-08 33.3 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KOS19223.1 - 6e-08 32.9 1.6 7.2e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 DUSP domain zf-ribbon_3 PF13248.1 KOS19223.1 - 0.35 10.1 1.0 3.1 7.1 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KOS19223.1 - 0.53 10.2 2.2 22 5.1 0.5 2.5 2 0 0 2 2 2 0 Zinc ribbon domain DUF2346 PF09803.4 KOS19224.1 - 0.0017 18.1 3.1 0.0041 16.9 2.2 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) SGT1 PF07093.6 KOS19225.1 - 0.00062 18.2 11.7 0.00099 17.6 8.1 1.2 1 0 0 1 1 1 1 SGT1 protein DUF788 PF05620.6 KOS19225.1 - 7.3 6.4 8.9 14 5.5 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF788) NUDIX_2 PF13869.1 KOS19226.1 - 2.1e-80 268.4 0.0 2.5e-80 268.2 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase UPF0047 PF01894.12 KOS19227.1 - 6.8e-41 138.7 0.0 8.3e-41 138.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 HemY_N PF07219.8 KOS19227.1 - 0.094 12.2 0.1 0.47 10.0 0.0 2.1 3 0 0 3 3 3 0 HemY protein N-terminus NAD_kinase PF01513.16 KOS19229.1 - 3.1e-69 232.9 0.0 4.6e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Serglycin PF04360.7 KOS19229.1 - 0.011 15.4 1.4 0.028 14.1 1.0 1.6 1 0 0 1 1 1 0 Serglycin Suf PF05843.9 KOS19229.1 - 0.32 10.6 5.8 0.5 10.0 4.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LIM_bind PF01803.11 KOS19229.1 - 0.85 8.6 7.2 1.7 7.6 5.0 1.4 1 0 0 1 1 1 0 LIM-domain binding protein EBP PF05241.7 KOS19230.1 - 4.8e-64 214.9 2.3 5.8e-64 214.6 1.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2823 PF11034.3 KOS19231.1 - 4.2e-29 100.4 10.2 4.6e-29 100.3 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) Activator-TraM PF11657.3 KOS19231.1 - 0.14 11.6 4.9 0.16 11.4 3.4 1.1 1 0 0 1 1 1 0 Transcriptional activator TraM RapA_C PF12137.3 KOS19231.1 - 1.7 7.4 5.2 1.8 7.3 3.6 1.0 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal MRP-S31 PF15433.1 KOS19231.1 - 2.6 7.4 7.3 2.7 7.3 5.1 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 PAP2 PF01569.16 KOS19232.1 - 1.1e-15 57.4 5.1 1.8e-15 56.7 3.3 1.6 1 1 0 1 1 1 1 PAP2 superfamily CitMHS PF03600.11 KOS19232.1 - 0.0022 16.6 2.3 0.0025 16.4 1.6 1.1 1 0 0 1 1 1 1 Citrate transporter PrgI PF12666.2 KOS19232.1 - 0.18 11.9 5.2 0.15 12.2 1.1 2.4 2 0 0 2 2 2 0 PrgI family protein IBR PF01485.16 KOS19233.1 - 2.1e-18 65.9 36.1 6.8e-12 45.0 4.6 4.1 3 1 1 4 4 4 2 IBR domain RWD PF05773.17 KOS19233.1 - 8e-18 64.3 0.0 1.4e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 KOS19233.1 - 7.9e-05 22.4 7.4 7.9e-05 22.4 5.1 3.6 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_4 PF15227.1 KOS19233.1 - 0.0024 17.7 2.2 0.0024 17.7 1.5 4.2 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KOS19233.1 - 0.0035 17.3 8.5 0.0035 17.3 5.9 4.1 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS19233.1 - 0.0045 16.6 7.9 0.0045 16.6 5.5 4.0 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KOS19233.1 - 2.6 7.8 38.2 0.031 13.9 5.7 4.2 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) NDT80_PhoG PF05224.7 KOS19234.1 - 2.4e-32 112.4 0.0 3.8e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF2011 PF09428.5 KOS19235.1 - 1.9e-24 86.0 11.1 3.1e-24 85.3 7.7 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) DUF3402 PF11882.3 KOS19236.1 - 7.8e-127 423.7 0.2 7.4e-115 384.2 0.0 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF3402) N1221 PF07923.8 KOS19236.1 - 1.7e-77 260.2 0.1 2.9e-77 259.4 0.0 1.4 1 0 0 1 1 1 1 N1221-like protein Mem_trans PF03547.13 KOS19236.1 - 0.029 12.6 3.4 0.046 12.0 2.3 1.3 1 0 0 1 1 1 0 Membrane transport protein Macoilin PF09726.4 KOS19236.1 - 0.35 9.0 30.5 0.006 14.9 16.5 1.5 2 0 0 2 2 2 0 Transmembrane protein Ndc1_Nup PF09531.5 KOS19236.1 - 1.8 6.9 12.5 2.9 6.1 8.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MARVEL PF01284.18 KOS19237.1 - 0.0034 17.1 16.7 0.0056 16.5 11.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 KOS19237.1 - 0.13 11.9 11.7 1.5 8.4 3.8 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF4027 PF13219.1 KOS19237.1 - 0.3 10.5 2.8 0.68 9.4 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) DUF4396 PF14342.1 KOS19237.1 - 0.46 10.6 0.0 0.46 10.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4396) RCR PF12273.3 KOS19237.1 - 0.48 10.9 4.4 1.1 9.8 0.9 2.6 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF2207 PF09972.4 KOS19237.1 - 2.3 6.6 3.8 5.1 5.5 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) BING4CT PF08149.6 KOS19238.1 - 5.9e-41 137.8 0.0 1.3e-37 127.1 0.0 3.5 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 KOS19238.1 - 2.5e-08 33.4 0.0 0.00095 18.9 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KOS19238.1 - 3.6e-05 22.7 0.2 0.001 17.9 0.0 2.3 1 1 0 2 2 2 1 Coatomer WD associated region Cytochrom_D1 PF02239.11 KOS19238.1 - 0.013 13.8 0.2 0.55 8.4 0.0 2.5 3 0 0 3 3 3 0 Cytochrome D1 heme domain MSC PF09402.5 KOS19239.1 - 4e-84 282.1 0.0 1.2e-81 274.0 0.0 2.2 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 KOS19239.1 - 1.3e-14 53.4 0.0 2.5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain DUF3350 PF11830.3 KOS19239.1 - 0.0038 17.2 0.4 4.3 7.4 0.1 3.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3350) Thymopoietin PF08198.6 KOS19239.1 - 0.1 12.1 0.3 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 Thymopoietin protein Mt_ATP-synt_B PF05405.9 KOS19240.1 - 2.4e-53 179.9 9.7 3.1e-53 179.5 6.8 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Orthopox_A5L PF06193.6 KOS19240.1 - 0.025 14.4 0.8 0.051 13.5 0.4 1.6 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like DUF1539 PF07560.6 KOS19240.1 - 0.053 13.3 0.6 0.11 12.3 0.3 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) CBF PF03914.12 KOS19241.1 - 2.3e-45 154.0 0.1 7e-45 152.4 0.0 1.8 2 0 0 2 2 2 1 CBF/Mak21 family CorA PF01544.13 KOS19242.1 - 1.3e-40 139.2 0.4 4.2e-40 137.6 0.3 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CSTF2_hinge PF14327.1 KOS19243.1 - 2.8e-30 104.2 1.7 2.8e-30 104.2 1.2 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KOS19243.1 - 5.3e-22 77.2 0.0 7.8e-22 76.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS19243.1 - 6.4e-17 61.2 0.0 1.3e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS19243.1 - 2e-08 33.9 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KOS19243.1 - 2.9e-08 32.8 3.9 2.9e-08 32.8 2.7 2.8 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal Spo7_2_N PF15407.1 KOS19243.1 - 0.089 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 COPIIcoated_ERV PF07970.7 KOS19244.1 - 2.4e-54 184.2 0.0 6.9e-54 182.8 0.0 1.7 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KOS19244.1 - 2.3e-33 114.0 0.0 3.6e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sel1 PF08238.7 KOS19245.1 - 1.8e-14 53.8 7.9 0.0005 20.6 0.1 4.4 4 0 0 4 4 4 3 Sel1 repeat TPR_11 PF13414.1 KOS19245.1 - 0.062 12.9 0.8 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 TPR repeat Proteasome PF00227.21 KOS19246.1 - 3.5e-44 150.3 0.0 4.4e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KOS19246.1 - 1.8e-12 46.2 0.2 3.6e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal WD40 PF00400.27 KOS19247.1 - 0.0045 16.8 0.3 0.018 14.8 0.1 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat Syntaxin-6_N PF09177.6 KOS19248.1 - 1.6 9.1 6.0 4.8 7.6 0.1 3.6 3 1 1 4 4 4 0 Syntaxin 6, N-terminal DUF1664 PF07889.7 KOS19248.1 - 7.9 6.2 8.2 2.3 8.0 0.1 3.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) Cytochrom_B561 PF03188.11 KOS19249.1 - 8e-05 22.4 13.0 8e-05 22.4 9.0 2.0 2 1 1 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KOS19249.1 - 0.0012 18.3 7.0 0.0012 18.3 4.8 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF2427) DOMON PF03351.12 KOS19249.1 - 0.0034 17.2 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Serglycin PF04360.7 KOS19249.1 - 2.6 7.7 10.4 4 7.1 0.2 2.4 2 0 0 2 2 2 0 Serglycin SdpI PF13630.1 KOS19249.1 - 6.4 6.5 7.1 0.9 9.2 0.1 2.6 2 0 0 2 2 2 0 SdpI/YhfL protein family AhpC-TSA_2 PF13911.1 KOS19250.1 - 2.5e-11 43.4 0.0 4.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KOS19250.1 - 0.00021 20.9 0.0 0.00038 20.1 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Rtf2 PF04641.7 KOS19250.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Tubulin_3 PF14881.1 KOS19251.1 - 2.7e-73 245.3 0.0 1.7e-72 242.7 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.4 KOS19251.1 - 5e-38 129.7 0.0 1.4e-37 128.2 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 KOS19251.1 - 2.7e-06 27.3 0.0 0.0085 15.9 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain CLU PF13236.1 KOS19252.1 - 5.6e-81 271.1 0.0 1e-80 270.3 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 KOS19252.1 - 7.9e-54 182.1 0.1 3.4e-53 180.0 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 KOS19252.1 - 4.7e-27 93.7 18.0 1.9e-10 40.5 1.1 3.7 1 1 4 5 5 5 5 Tetratricopeptide repeat CLU_N PF15044.1 KOS19252.1 - 1.2e-22 79.8 0.1 2.5e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 KOS19252.1 - 7.3e-16 57.5 0.5 0.00013 21.8 0.0 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KOS19252.1 - 0.00014 21.4 8.5 0.041 13.5 1.9 3.5 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.1 KOS19252.1 - 0.00036 20.1 4.0 0.095 12.5 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KOS19252.1 - 0.035 14.0 0.2 0.035 14.0 0.1 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 KOS19252.1 - 0.16 12.2 2.8 53 4.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat INCENP_N PF12178.3 KOS19252.1 - 3.5 7.2 6.7 3.6 7.2 0.0 3.7 5 0 0 5 5 5 0 Chromosome passenger complex (CPC) protein INCENP N terminal DUF4407 PF14362.1 KOS19252.1 - 7.1 5.4 7.6 14 4.5 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nuc_sug_transp PF04142.10 KOS19253.1 - 6.8e-10 38.4 0.7 1.4e-09 37.4 0.3 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 KOS19253.1 - 1.1e-07 31.9 22.6 6.8e-05 22.9 2.6 3.2 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 KOS19253.1 - 0.05 13.2 21.8 0.12 11.9 0.4 2.6 3 0 0 3 3 3 0 Triose-phosphate Transporter family UPF0114 PF03350.11 KOS19253.1 - 1.2 9.0 9.7 4.8 7.1 0.3 4.3 3 2 0 4 4 4 0 Uncharacterized protein family, UPF0114 DUF1469 PF07332.6 KOS19253.1 - 2.1 8.1 13.7 0.045 13.4 0.8 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1469) PAP_central PF04928.12 KOS19254.1 - 6.2e-102 339.7 0.0 8.4e-102 339.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KOS19254.1 - 6.9e-39 132.8 1.3 2.2e-38 131.2 0.2 2.0 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KOS19254.1 - 2.9e-07 30.7 0.1 6.8e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Peptidase_S49 PF01343.13 KOS19254.1 - 0.044 13.5 0.1 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 Fork_head PF00250.13 KOS19255.1 - 2.2e-29 101.3 0.2 4.2e-29 100.4 0.1 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KOS19255.1 - 5.8e-10 39.1 0.0 9.8e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain PAT1 PF09770.4 KOS19255.1 - 3.7 5.6 7.3 4.7 5.3 5.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_L29e PF01779.12 KOS19256.1 - 4.2e-23 80.9 9.2 7.9e-23 80.0 6.4 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family PAP_assoc PF03828.14 KOS19257.1 - 5.3e-08 32.6 2.3 2.6e-07 30.4 1.6 2.0 1 1 0 1 1 1 1 Cid1 family poly A polymerase PYRIN PF02758.11 KOS19257.1 - 0.15 11.8 2.1 2 8.1 0.6 2.6 2 1 0 2 2 2 0 PAAD/DAPIN/Pyrin domain Yippee-Mis18 PF03226.9 KOS19258.1 - 2.2e-21 75.7 0.4 2.5e-21 75.5 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 KOS19258.1 - 0.0027 17.6 0.1 0.33 10.9 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease DUF2039 PF10217.4 KOS19258.1 - 0.046 13.7 1.4 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Evr1_Alr PF04777.8 KOS19258.1 - 0.063 13.1 1.6 1.3 9.0 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family zf-CHY PF05495.7 KOS19258.1 - 0.081 13.0 0.9 12 6.0 0.1 2.2 2 0 0 2 2 2 0 CHY zinc finger DUF3268 PF11672.3 KOS19258.1 - 0.14 12.2 1.2 2.1 8.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) Endonuclease_7 PF02945.10 KOS19258.1 - 0.77 9.5 3.2 1.7 8.4 2.2 1.6 1 1 0 1 1 1 0 Recombination endonuclease VII Sen15 PF09631.5 KOS19259.1 - 9.8e-29 99.5 0.0 1.3e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Sen15 protein An_peroxidase PF03098.10 KOS19260.1 - 2.3e-85 286.9 0.0 1.9e-67 227.8 0.0 2.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 KOS19260.1 - 0.031 12.7 0.0 0.052 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 WD40 PF00400.27 KOS19261.1 - 7.6e-55 180.9 15.5 6.2e-11 41.7 0.7 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.6 KOS19261.1 - 2.7e-16 58.5 1.2 4.6e-16 57.7 0.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 KOS19261.1 - 0.0011 18.6 0.1 6.3 6.4 0.0 4.2 3 1 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KOS19261.1 - 0.047 12.7 0.1 4 6.4 0.0 2.8 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Cyclin_N PF00134.18 KOS19262.1 - 7.4e-11 41.7 0.1 2.1e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain adh_short PF00106.20 KOS19263.1 - 2.3e-22 79.6 1.0 3.5e-22 79.0 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS19263.1 - 2.7e-12 46.7 1.2 5.4e-12 45.7 0.5 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KOS19263.1 - 7.2e-07 29.2 0.0 9.4e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2493 PF10686.4 KOS19263.1 - 0.14 11.7 1.0 3.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2493) Iso_dh PF00180.15 KOS19264.1 - 2.3e-126 421.4 0.0 2.8e-126 421.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PHD PF00628.24 KOS19265.1 - 1.5e-10 40.6 5.5 1.9e-10 40.2 3.8 1.2 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KOS19265.1 - 0.051 12.9 2.3 0.081 12.2 1.6 1.4 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 KOS19265.1 - 0.051 13.3 1.3 0.087 12.5 0.9 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Actin PF00022.14 KOS19267.1 - 3e-28 98.3 0.0 7.2e-18 64.1 0.0 3.0 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KOS19267.1 - 0.037 12.6 0.0 0.69 8.4 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Pex14_N PF04695.8 KOS19267.1 - 0.18 11.8 7.2 0.092 12.7 0.9 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MFS_1 PF07690.11 KOS19268.1 - 2.9e-20 72.2 28.2 2.1e-12 46.4 4.7 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KOS19268.1 - 5.2e-07 28.4 3.7 6e-06 24.9 1.3 2.6 2 1 0 2 2 2 1 MFS/sugar transport protein ATG22 PF11700.3 KOS19268.1 - 3.8e-05 22.3 0.1 3.8e-05 22.3 0.1 3.3 3 2 1 4 4 4 2 Vacuole effluxer Atg22 like TraL PF07178.6 KOS19268.1 - 0.071 13.1 0.3 1.9 8.5 0.0 2.8 2 0 0 2 2 2 0 TraL protein LacY_symp PF01306.14 KOS19268.1 - 0.37 9.3 5.1 0.074 11.5 0.3 2.0 2 0 0 2 2 2 0 LacY proton/sugar symporter DUF3123 PF11321.3 KOS19268.1 - 3 8.1 5.6 0.57 10.4 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Sporozoite_P67 PF05642.6 KOS19268.1 - 4.9 4.8 5.1 0.8 7.4 0.6 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Fungal_trans_2 PF11951.3 KOS19269.1 - 1e-07 30.9 0.2 2.5e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3527 PF12043.3 KOS19269.1 - 0.02 14.4 0.8 0.028 13.9 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) DUF3373 PF11853.3 KOS19269.1 - 0.036 12.6 0.0 0.042 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Phostensin_N PF13916.1 KOS19269.1 - 0.085 12.8 2.6 0.16 12.0 1.8 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal RRP14 PF15459.1 KOS19269.1 - 0.93 9.6 6.6 2.2 8.4 4.6 1.6 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Med10 PF09748.4 KOS19270.1 - 3.3e-40 136.8 0.1 3.9e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Nup54 PF13874.1 KOS19270.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 TPR_11 PF13414.1 KOS19271.1 - 3.2e-39 132.4 11.3 1.6e-14 53.2 0.3 5.9 4 2 2 6 6 6 4 TPR repeat TPR_1 PF00515.23 KOS19271.1 - 1.1e-30 103.9 9.2 4.6e-06 26.0 0.1 7.4 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 KOS19271.1 - 1.1e-30 102.9 10.5 0.00041 20.0 0.0 8.3 7 2 1 8 8 8 6 Tetratricopeptide repeat DnaJ PF00226.26 KOS19271.1 - 2.6e-27 94.3 5.4 3.8e-27 93.8 2.7 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.1 KOS19271.1 - 4.5e-25 87.7 0.7 2e-06 28.2 0.0 5.7 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KOS19271.1 - 4.3e-24 84.6 5.2 2.2e-06 27.9 0.1 5.7 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KOS19271.1 - 1.9e-17 62.9 6.4 1.8e-05 24.6 0.0 5.1 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 KOS19271.1 - 6.4e-16 57.4 5.2 0.0032 17.9 0.2 8.3 3 3 5 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 KOS19271.1 - 4.8e-15 54.4 7.4 0.0084 16.2 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KOS19271.1 - 2.4e-13 48.8 13.8 0.013 15.2 0.1 7.1 6 2 1 7 7 6 5 Tetratricopeptide repeat Apc3 PF12895.2 KOS19271.1 - 7.9e-13 48.3 3.0 3.5e-05 23.8 0.1 4.0 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KOS19271.1 - 1.6e-11 43.0 1.0 0.032 14.0 0.0 6.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 KOS19271.1 - 1.8e-10 40.5 1.5 0.031 14.1 0.0 4.9 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 KOS19271.1 - 9.7e-08 31.9 8.3 0.77 10.3 0.0 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 KOS19271.1 - 1.5e-05 24.2 4.0 0.97 8.4 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 KOS19271.1 - 0.0027 17.9 4.7 4.2 8.0 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat DUF2225 PF09986.4 KOS19271.1 - 0.0059 16.0 0.3 0.033 13.6 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) Coatomer_E PF04733.9 KOS19271.1 - 0.0073 15.5 0.5 2.4 7.3 0.1 3.0 2 1 2 4 4 4 1 Coatomer epsilon subunit MIT PF04212.13 KOS19271.1 - 0.0077 16.0 4.5 0.79 9.6 0.3 3.1 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain BTAD PF03704.12 KOS19271.1 - 0.062 13.6 2.4 17 5.7 0.0 4.0 3 1 0 4 4 4 0 Bacterial transcriptional activator domain RRM_3 PF08777.6 KOS19271.1 - 0.38 10.6 3.2 4 7.3 0.0 3.1 2 1 1 3 3 3 0 RNA binding motif TPR_10 PF13374.1 KOS19271.1 - 0.98 9.4 8.2 58 3.8 0.0 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF3597 PF12200.3 KOS19271.1 - 4.7 7.6 11.1 0.29 11.5 0.2 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3597) zf-FCS PF06467.9 KOS19272.1 - 0.0027 17.2 0.1 0.69 9.6 0.0 2.2 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif Stm1_N PF09598.5 KOS19273.1 - 4.8e-11 43.2 1.3 4.8e-11 43.2 0.9 4.1 3 2 1 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.10 KOS19273.1 - 0.00065 20.1 10.0 0.00065 20.1 7.0 2.4 3 1 0 4 4 4 1 Hyaluronan / mRNA binding family PfkB PF00294.19 KOS19274.1 - 6e-67 225.8 0.0 6.7e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribosomal_L2_C PF03947.13 KOS19275.1 - 1.7e-37 128.1 3.8 1.7e-37 128.1 2.6 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KOS19275.1 - 9e-15 54.4 0.1 1.9e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain eRF1_2 PF03464.10 KOS19276.1 - 1.8e-45 154.4 0.1 3.5e-45 153.5 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KOS19276.1 - 3.3e-40 136.8 0.6 6.9e-40 135.8 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KOS19276.1 - 1.9e-28 98.6 0.0 3.4e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 KOS19276.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PH PF00169.24 KOS19277.1 - 2.6e-06 27.5 0.1 6.5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 KOS19277.1 - 0.00043 19.7 0.0 0.00094 18.6 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Beta_propel PF09826.4 KOS19277.1 - 0.16 10.2 0.0 0.29 9.4 0.0 1.3 1 0 0 1 1 1 0 Beta propeller domain WHIM2 PF15613.1 KOS19278.1 - 0.05 13.5 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 DUF1770 PF08589.5 KOS19279.1 - 1.4e-22 80.1 0.0 1.8e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Complex1_LYR_1 PF13232.1 KOS19280.1 - 2.5e-07 30.7 0.0 5.2e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KOS19280.1 - 1.3e-06 28.1 0.0 2.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KOS19280.1 - 3.1e-05 24.4 0.0 4.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like RNA_pol_L_2 PF13656.1 KOS19281.1 - 1.7e-30 104.2 0.0 2.2e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KOS19281.1 - 7.7e-11 40.9 0.0 1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Herpes_pp85 PF04637.7 KOS19282.1 - 0.0022 16.3 0.0 0.0028 16.0 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) G10 PF01125.12 KOS19283.1 - 4e-54 182.1 0.5 4.7e-54 181.8 0.4 1.0 1 0 0 1 1 1 1 G10 protein TauD PF02668.11 KOS19285.1 - 1.3e-27 97.0 0.0 1.8e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UCH PF00443.24 KOS19286.1 - 2.4e-35 121.9 0.0 3.1e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS19286.1 - 1e-05 25.1 0.0 1.9e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2387 PF09526.5 KOS19286.1 - 0.11 12.3 0.2 8.7 6.3 0.0 2.7 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Actino_peptide PF14408.1 KOS19286.1 - 0.23 11.3 9.5 0.4 10.6 5.1 2.5 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes Metallophos PF00149.23 KOS19287.1 - 1.2e-41 142.3 1.0 1.8e-41 141.7 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short_C2 PF13561.1 KOS19288.1 - 1.1e-22 81.0 1.3 1.4e-22 80.7 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KOS19288.1 - 8e-22 77.9 2.3 1.7e-21 76.8 1.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS19288.1 - 6.3e-08 32.4 2.0 1.3e-07 31.4 1.4 1.6 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 KOS19288.1 - 0.0061 15.7 0.2 0.015 14.4 0.1 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KOS19288.1 - 0.039 13.6 0.5 0.079 12.6 0.2 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KOS19288.1 - 0.066 12.6 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.16 KOS19288.1 - 0.079 12.3 0.3 1.1 8.5 0.1 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KOS19288.1 - 0.081 12.7 0.2 0.25 11.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 KOS19288.1 - 0.11 12.1 2.7 0.074 12.7 0.5 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sulfatase PF00884.18 KOS19289.1 - 1.2e-20 73.8 0.1 1.4e-19 70.4 0.1 2.3 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 KOS19289.1 - 5e-08 32.6 0.0 7.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KOS19289.1 - 0.02 13.3 0.0 0.029 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF4021 PF13213.1 KOS19289.1 - 0.26 10.9 0.7 0.6 9.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4021) SR-25 PF10500.4 KOS19289.1 - 3.5 7.0 12.2 5.7 6.3 8.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CBFB_NFYA PF02045.10 KOS19292.1 - 3.7e-30 104.2 4.6 6.8e-30 103.3 3.2 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B PAT1 PF09770.4 KOS19292.1 - 9.4 4.3 9.1 12 4.0 6.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rax2 PF12768.2 KOS19293.1 - 1.9e-93 312.7 5.3 7.1e-82 274.7 0.0 4.0 4 0 0 4 4 4 3 Cortical protein marker for cell polarity Aurora-A_bind PF09041.5 KOS19293.1 - 0.02 14.6 0.1 0.068 12.9 0.1 2.0 1 0 0 1 1 1 0 Aurora-A binding zf-H2C2_2 PF13465.1 KOS19294.1 - 1.3e-12 47.3 12.4 5e-08 32.8 0.2 3.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KOS19294.1 - 2.2e-10 40.2 11.7 1.5e-05 25.0 3.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS19294.1 - 2.8e-08 33.5 7.9 1.4e-05 25.0 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KOS19294.1 - 1.9e-05 24.3 8.1 0.014 15.2 1.4 2.6 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KOS19294.1 - 5.1e-05 23.3 2.0 5.1e-05 23.3 1.4 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KOS19294.1 - 0.00017 21.6 5.2 0.00049 20.1 1.8 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KOS19294.1 - 0.031 14.3 2.8 0.045 13.8 1.4 1.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KOS19294.1 - 0.48 10.2 6.2 3.2 7.5 4.3 2.1 1 1 0 1 1 1 0 BED zinc finger P34-Arc PF04045.9 KOS19295.1 - 8.8e-100 332.9 0.6 1.1e-99 332.6 0.4 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc SNase PF00565.12 KOS19296.1 - 1.9e-25 89.2 0.1 2.9e-25 88.6 0.1 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DDE_Tnp_1_2 PF13586.1 KOS19296.1 - 0.086 13.0 0.2 0.2 11.8 0.1 1.7 1 1 0 1 1 1 0 Transposase DDE domain Ribosomal_S13_N PF08069.7 KOS19297.1 - 7.9e-30 102.4 0.4 1.5e-29 101.5 0.3 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KOS19297.1 - 7.7e-22 76.8 0.1 2.7e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S15 PAX PF00292.13 KOS19297.1 - 0.039 13.6 0.2 0.089 12.5 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain HTH_32 PF13565.1 KOS19297.1 - 0.12 13.2 0.2 0.29 11.9 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain VRR_NUC PF08774.6 KOS19298.1 - 0.001 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 VRR-NUC domain SF3b1 PF08920.5 KOS19299.1 - 2.2e-36 125.1 7.9 2.5e-35 121.6 0.6 2.4 1 1 1 2 2 2 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KOS19299.1 - 8.9e-17 61.1 0.9 0.01 16.1 0.0 7.4 6 3 3 9 9 9 7 HEAT repeats HEAT PF02985.17 KOS19299.1 - 6.3e-12 44.5 8.1 1 9.6 0.0 9.6 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 KOS19299.1 - 3.5e-11 43.2 1.6 0.44 11.1 0.0 8.2 7 2 2 9 9 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KOS19299.1 - 1.2e-05 25.5 0.1 0.58 10.5 0.0 5.6 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KOS19299.1 - 0.00027 19.4 0.4 0.13 10.5 0.0 3.5 2 2 1 3 3 3 2 Adaptin N terminal region UPF0236 PF06782.6 KOS19299.1 - 0.00053 18.5 0.0 0.00093 17.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0236) NUC173 PF08161.7 KOS19299.1 - 0.0029 16.9 0.4 4.6 6.5 0.0 3.9 4 0 0 4 4 4 1 NUC173 domain CLASP_N PF12348.3 KOS19299.1 - 0.0087 15.4 0.1 1.4 8.2 0.0 3.8 5 0 0 5 5 5 1 CLASP N terminal RRM_1 PF00076.17 KOS19300.1 - 4.2e-16 58.3 0.0 9.4e-09 34.7 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS19300.1 - 1.6e-12 47.1 0.0 8.9e-05 22.3 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS19300.1 - 0.001 18.8 0.1 4.2 7.2 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phlebovirus_NSM PF07246.6 KOS19302.1 - 0.0003 20.0 1.7 0.00046 19.4 1.2 1.2 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M bZIP_2 PF07716.10 KOS19302.1 - 0.1 12.4 15.3 0.17 11.7 10.6 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Tom37_C PF11801.3 KOS19302.1 - 0.21 11.4 2.9 0.3 10.9 2.0 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain CMS1 PF14617.1 KOS19302.1 - 0.61 9.1 5.8 0.84 8.6 4.1 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Tho2 PF11262.3 KOS19302.1 - 0.76 8.7 4.0 1 8.3 2.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 bZIP_1 PF00170.16 KOS19302.1 - 1.3 9.0 16.2 1.4 8.8 10.7 1.5 1 1 0 1 1 1 0 bZIP transcription factor Atg14 PF10186.4 KOS19302.1 - 2.8 6.8 8.5 3.8 6.3 5.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_M18 PF02127.10 KOS19304.1 - 1.3e-168 560.9 0.0 7.1e-168 558.5 0.0 1.8 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KOS19304.1 - 0.00037 19.3 0.0 0.019 13.7 0.0 2.2 1 1 0 2 2 2 2 M42 glutamyl aminopeptidase GIY-YIG PF01541.19 KOS19305.1 - 0.82 10.0 3.5 1.4 9.3 2.4 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain RRXRR PF14239.1 KOS19305.1 - 3 7.2 10.9 3.7 6.9 7.5 1.2 1 0 0 1 1 1 0 RRXRR protein Aldedh PF00171.17 KOS19309.1 - 1.5e-167 557.6 0.0 1.7e-167 557.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Abhydrolase_7 PF12715.2 KOS19310.1 - 0.083 11.7 0.1 0.76 8.6 0.0 2.0 2 0 0 2 2 2 0 Abhydrolase family p450 PF00067.17 KOS19311.1 - 2.1e-81 273.7 0.0 2.6e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribonuclease PF00545.15 KOS19313.1 - 5e-15 55.3 0.1 6.1e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 ribonuclease BATS PF06968.8 KOS19314.1 - 1.5e-29 101.6 0.0 3.4e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KOS19314.1 - 8.2e-16 58.6 0.1 1.3e-15 57.9 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DegV PF02645.11 KOS19314.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 MFS_1 PF07690.11 KOS19315.1 - 7.2e-32 110.4 31.3 7.2e-32 110.4 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS19315.1 - 1.3e-08 33.8 8.4 1.3e-08 33.8 5.9 2.5 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KOS19315.1 - 7.7e-06 24.3 6.0 1.2e-05 23.7 3.7 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RGS PF00615.14 KOS19316.1 - 2.3e-06 27.6 0.1 5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain SET PF00856.23 KOS19317.1 - 1.3e-11 45.1 0.0 3.9e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 KOS19317.1 - 0.00024 20.8 13.5 0.00056 19.7 9.4 1.7 1 0 0 1 1 1 1 MYND finger TPR_12 PF13424.1 KOS19317.1 - 0.0019 18.0 1.1 0.16 11.9 0.2 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat GST_C_2 PF13410.1 KOS19318.1 - 3.1e-05 23.7 0.2 6.8e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KOS19318.1 - 0.00019 21.6 0.0 0.00049 20.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KOS19318.1 - 0.0087 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KOS19318.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain CMD PF02627.15 KOS19319.1 - 0.014 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family DUF2787 PF10980.3 KOS19319.1 - 0.053 13.4 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2787) Sugar_tr PF00083.19 KOS19320.1 - 8e-68 229.0 11.6 9.1e-68 228.8 8.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS19320.1 - 2.1e-07 29.9 29.6 2.8e-07 29.5 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HMG_box PF00505.14 KOS19321.1 - 6.8e-24 83.9 1.0 9.1e-24 83.5 0.7 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KOS19321.1 - 7.3e-17 61.5 0.5 9.6e-17 61.1 0.4 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KOS19321.1 - 0.0047 16.6 3.0 0.0078 15.9 2.1 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box 5 GFO_IDH_MocA PF01408.17 KOS19323.1 - 3.9e-09 37.0 0.1 6.8e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KOS19323.1 - 0.00019 21.1 0.4 0.0024 17.6 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Herpes_gE PF02480.11 KOS19324.1 - 0.013 13.7 0.0 0.019 13.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3115 PF11312.3 KOS19324.1 - 0.11 11.3 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) PGM_PMM_I PF02878.11 KOS19325.1 - 2.8e-33 114.3 0.0 4.3e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KOS19325.1 - 6.6e-25 87.3 0.0 1.1e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KOS19325.1 - 5.3e-16 58.8 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KOS19325.1 - 7.2e-09 35.5 0.0 1.6e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.19 KOS19326.1 - 5e-24 85.4 0.0 5.7e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Exonuclease SET PF00856.23 KOS19327.1 - 6.2e-07 29.8 0.5 1.7e-05 25.2 0.3 2.3 1 1 0 1 1 1 1 SET domain Ribosomal_S19 PF00203.16 KOS19328.1 - 5.7e-32 109.1 0.2 9.4e-32 108.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 NUDIX PF00293.23 KOS19329.1 - 0.0031 17.1 0.0 0.0067 16.0 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain zf-C2H2 PF00096.21 KOS19332.1 - 1.5e-12 47.0 11.4 2.2e-06 27.6 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS19332.1 - 5.1e-10 38.9 10.8 0.00011 22.2 3.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KOS19332.1 - 1.3e-08 34.7 11.9 5.3e-07 29.6 3.4 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KOS19332.1 - 6.9e-07 29.2 5.3 0.00027 20.9 0.7 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS19332.1 - 1.4e-06 28.3 4.3 9.4e-05 22.4 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KOS19332.1 - 0.00025 20.8 7.0 0.012 15.5 0.1 3.0 2 1 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 KOS19332.1 - 0.91 9.3 6.8 1.2 8.9 2.2 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.1 KOS19332.1 - 6.1 6.6 7.2 9.2 6.0 1.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Glyco_hydro_16 PF00722.16 KOS19333.1 - 5.1e-38 130.1 1.4 7.9e-38 129.5 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF202 PF02656.10 KOS19334.1 - 5e-23 81.1 1.8 5e-23 81.1 1.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF202) ATP_bind_4 PF01902.12 KOS19334.1 - 3e-20 72.5 0.0 3e-15 56.1 0.0 3.2 3 0 0 3 3 3 2 ATP-binding region Ribonuc_L-PSP PF01042.16 KOS19334.1 - 1e-11 44.6 0.4 1.3e-05 24.9 0.0 4.0 3 1 0 3 3 3 2 Endoribonuclease L-PSP Voldacs PF03517.8 KOS19334.1 - 0.00042 20.1 0.0 0.00042 20.1 0.0 3.1 3 1 1 4 4 4 1 Regulator of volume decrease after cellular swelling AAA_11 PF13086.1 KOS19335.1 - 8.7e-60 202.2 0.6 4.4e-59 199.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KOS19335.1 - 1e-45 155.6 0.0 2.2e-45 154.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS19335.1 - 1.1e-13 50.6 0.1 2.4e-12 46.4 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KOS19335.1 - 3.8e-11 42.9 0.0 2.8e-09 36.8 0.0 3.0 2 1 0 2 2 1 1 AAA domain DUF2075 PF09848.4 KOS19335.1 - 6.2e-07 28.7 0.2 2.3e-05 23.5 0.1 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KOS19335.1 - 9.6e-07 28.8 0.0 5.4e-06 26.3 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KOS19335.1 - 7.5e-06 25.4 0.0 4.3e-05 22.9 0.0 2.1 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 KOS19335.1 - 4e-05 23.2 0.0 0.13 11.7 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KOS19335.1 - 0.00018 21.0 0.1 0.0013 18.2 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KOS19335.1 - 0.00023 21.2 0.2 0.0076 16.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 KOS19335.1 - 0.00045 19.5 0.0 0.044 12.9 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.1 KOS19335.1 - 0.00051 19.4 0.1 0.0093 15.3 0.1 2.7 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 KOS19335.1 - 0.00075 18.4 0.0 0.0014 17.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Helicase_RecD PF05127.9 KOS19335.1 - 0.00076 19.1 0.0 0.035 13.7 0.0 2.4 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.1 KOS19335.1 - 0.0023 17.9 0.1 0.0072 16.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain 4HB_MCP_1 PF12729.2 KOS19335.1 - 0.0028 17.0 0.1 0.0061 15.9 0.1 1.5 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction Flavi_DEAD PF07652.9 KOS19335.1 - 0.0029 17.3 0.0 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_10 PF12846.2 KOS19335.1 - 0.0039 16.6 0.0 0.024 14.0 0.0 2.1 1 1 1 2 2 2 1 AAA-like domain TrwB_AAD_bind PF10412.4 KOS19335.1 - 0.0039 15.8 0.0 0.007 15.0 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.12 KOS19335.1 - 0.005 16.2 0.0 0.014 14.8 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein Zot PF05707.7 KOS19335.1 - 0.0058 16.1 0.2 0.054 12.9 0.0 2.7 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA PF00004.24 KOS19335.1 - 0.011 15.9 0.5 0.064 13.4 0.0 2.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS19335.1 - 0.013 15.2 0.1 0.072 12.8 0.0 2.3 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KOS19335.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 KOS19335.1 - 0.057 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family UvrD_C PF13361.1 KOS19335.1 - 0.061 12.7 0.6 1.9 7.8 0.0 2.5 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain AAA_28 PF13521.1 KOS19335.1 - 0.063 13.2 0.2 16 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 KOS19335.1 - 0.1 11.5 0.0 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase NTPase_1 PF03266.10 KOS19335.1 - 0.21 11.2 1.7 2.9 7.5 0.0 2.8 3 0 0 3 3 3 0 NTPase AAA_17 PF13207.1 KOS19335.1 - 7.2 7.4 7.1 1.5 9.6 0.9 3.0 2 2 0 2 2 2 0 AAA domain Topoisom_I_N PF02919.10 KOS19336.1 - 2.7e-92 307.9 6.0 2.7e-92 307.9 4.2 3.7 5 0 0 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KOS19336.1 - 3.7e-84 281.5 4.9 3.7e-84 281.5 3.4 2.2 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KOS19336.1 - 9.7e-31 105.2 0.3 9.7e-31 105.2 0.2 2.4 2 0 0 2 2 2 1 C-terminal topoisomerase domain ATP-synt PF00231.14 KOS19337.1 - 4.3e-71 239.6 5.3 4.9e-71 239.4 3.6 1.0 1 0 0 1 1 1 1 ATP synthase Amino_oxidase PF01593.19 KOS19338.1 - 9.9e-85 285.2 0.1 3.3e-84 283.5 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase HMG_box_2 PF09011.5 KOS19338.1 - 2.4e-08 34.2 1.5 5.5e-08 33.0 1.1 1.6 1 0 0 1 1 1 1 HMG-box domain NAD_binding_8 PF13450.1 KOS19338.1 - 3e-08 33.5 0.1 8.6e-08 32.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 KOS19338.1 - 3e-07 30.5 3.5 3.7e-07 30.3 1.4 2.0 2 1 0 2 2 2 1 HMG (high mobility group) box SWIRM PF04433.12 KOS19338.1 - 3.3e-05 23.9 0.0 7.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain DAO PF01266.19 KOS19338.1 - 0.0006 18.8 0.1 0.014 14.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApoO PF09769.4 KOS19339.1 - 1.5e-46 157.9 0.9 5.6e-46 156.1 0.0 2.0 1 1 1 2 2 2 1 Apolipoprotein O Peptidase_M3 PF01432.15 KOS19340.1 - 4e-115 385.4 0.0 7.4e-115 384.5 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.1 KOS19340.1 - 0.061 12.6 0.1 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like DUF2764 PF10962.3 KOS19340.1 - 0.08 12.1 0.3 0.29 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2764) MMR_HSR1 PF01926.18 KOS19341.1 - 2.9e-17 62.6 0.2 1.5e-15 57.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS19341.1 - 3.2e-07 29.7 0.1 2e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KOS19341.1 - 5.7e-05 22.3 0.5 0.00013 21.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KOS19341.1 - 0.0034 17.2 6.4 0.042 13.6 0.0 3.3 3 0 0 3 3 3 1 Dynamin family Sporozoite_P67 PF05642.6 KOS19341.1 - 0.0051 14.7 1.6 0.0069 14.3 1.1 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen AIG1 PF04548.11 KOS19341.1 - 0.0067 15.5 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 KOS19341.1 - 0.039 14.4 0.1 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein BSP_II PF05432.6 KOS19341.1 - 0.043 13.1 12.5 0.07 12.4 8.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) ArgK PF03308.11 KOS19341.1 - 0.052 12.3 0.1 0.11 11.3 0.1 1.4 1 0 0 1 1 1 0 ArgK protein Daxx PF03344.10 KOS19341.1 - 0.061 11.8 10.5 0.085 11.3 7.3 1.1 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 KOS19341.1 - 0.36 9.7 6.6 0.63 8.9 4.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pox_Ag35 PF03286.9 KOS19341.1 - 0.5 9.8 8.6 1.2 8.6 6.0 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TEX19 PF15553.1 KOS19341.1 - 1.5 8.6 7.4 3.1 7.6 5.2 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 Nol1_Nop2_Fmu PF01189.12 KOS19342.1 - 6.9e-95 317.6 0.0 9.6e-95 317.1 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 KOS19342.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 KOS19342.1 - 0.045 13.2 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 KOS19342.1 - 0.14 11.7 0.0 2.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Met-10+ like-protein DKCLD PF08068.7 KOS19343.1 - 1.3e-29 101.8 0.1 9.4e-29 99.1 0.1 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 KOS19343.1 - 4e-23 82.2 5.3 1.5e-21 77.0 0.2 3.6 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KOS19343.1 - 5.2e-21 74.1 0.6 1.1e-20 73.1 0.4 1.6 1 0 0 1 1 1 1 PUA domain RR_TM4-6 PF06459.7 KOS19343.1 - 1.4 8.7 12.1 2.2 8.1 8.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAC3_GANP PF03399.11 KOS19345.1 - 1e-38 132.9 0.2 1.6e-38 132.3 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DER1 PF04511.10 KOS19346.1 - 1.5e-23 83.3 4.9 1.7e-23 83.1 3.4 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 KOS19346.1 - 0.41 10.6 15.4 0.81 9.7 7.7 3.3 2 1 0 2 2 2 0 Rhomboid family Bromodomain PF00439.20 KOS19352.1 - 4.3e-30 103.4 0.1 3.4e-15 55.7 0.0 2.9 3 0 0 3 3 3 2 Bromodomain Utp12 PF04003.7 KOS19353.1 - 1.3e-21 76.5 0.0 2e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family NUDIX PF00293.23 KOS19355.1 - 0.00023 20.8 0.0 0.0015 18.1 0.0 2.0 1 1 0 1 1 1 1 NUDIX domain Pkinase PF00069.20 KOS19356.1 - 7.4e-59 199.0 0.0 1e-58 198.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19356.1 - 1e-31 109.9 0.0 3.3e-30 105.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KOS19356.1 - 0.0045 15.8 0.0 0.0063 15.3 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase HSP70 PF00012.15 KOS19357.1 - 3.5e-08 31.8 0.1 2.6e-07 28.9 0.0 1.9 2 0 0 2 2 2 2 Hsp70 protein AA_permease PF00324.16 KOS19358.1 - 4e-94 315.6 47.7 5e-94 315.3 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KOS19358.1 - 2.5e-23 82.2 46.9 3.7e-23 81.7 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease Fes1 PF08609.5 KOS19360.1 - 9.1e-32 109.4 2.2 1.8e-31 108.4 1.5 1.5 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 KOS19360.1 - 4.7e-09 36.4 12.9 2e-05 24.7 2.2 2.0 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 KOS19360.1 - 1.8e-07 31.4 5.8 7.2e-06 26.3 1.3 3.0 3 1 1 4 4 4 2 HEAT-like repeat Arm PF00514.18 KOS19360.1 - 5.7e-07 29.1 1.1 0.014 15.1 0.1 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KOS19360.1 - 2.8e-05 23.8 0.7 0.0029 17.5 0.0 3.0 2 0 0 2 2 2 1 HEAT repeat Ribosomal_L5_C PF00673.16 KOS19361.1 - 7.4e-24 83.3 0.0 1.1e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KOS19361.1 - 0.0013 18.5 0.0 0.0068 16.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 COX5A PF02284.11 KOS19362.1 - 9.4e-36 122.0 0.7 9.4e-36 122.0 0.5 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase subunit Va Actin PF00022.14 KOS19363.1 - 2.9e-159 529.6 0.0 3.3e-159 529.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KOS19363.1 - 0.043 14.2 0.0 0.13 12.6 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RAI1 PF08652.6 KOS19364.1 - 5.1e-28 96.6 0.0 9.5e-28 95.7 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease HDA2-3 PF11496.3 KOS19365.1 - 6.2e-09 35.0 1.9 2.5e-05 23.2 0.0 2.6 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 TMF_TATA_bd PF12325.3 KOS19365.1 - 0.0037 16.9 1.5 0.0037 16.9 1.0 3.3 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 KOS19365.1 - 0.01 15.0 0.7 0.044 12.9 0.1 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein TBPIP PF07106.8 KOS19365.1 - 0.02 14.4 20.8 0.075 12.5 2.8 2.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMCO5 PF14992.1 KOS19365.1 - 0.09 11.8 18.8 0.083 12.0 11.5 1.9 1 1 0 1 1 1 0 TMCO5 family PDCD2_C PF04194.8 KOS19365.1 - 1.1 8.8 4.5 3.6 7.1 3.1 1.8 1 1 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Transglut_core PF01841.14 KOS19366.1 - 2.6e-10 40.5 0.3 6.9e-10 39.1 0.2 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Pkinase PF00069.20 KOS19367.1 - 9e-69 231.4 0.0 1.6e-68 230.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19367.1 - 3e-49 167.4 0.0 4.3e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS19367.1 - 4e-06 26.0 0.0 1.4e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.6 KOS19367.1 - 0.07 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) UCH_1 PF13423.1 KOS19368.1 - 3.7e-47 161.2 0.0 2.2e-38 132.3 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 KOS19368.1 - 2.5e-10 39.9 0.0 6.5e-10 38.5 0.0 1.5 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Porin_3 PF01459.17 KOS19369.1 - 4.2e-82 275.5 0.0 5e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin Apq12 PF12716.2 KOS19371.1 - 0.00012 21.6 9.9 0.00021 20.8 6.8 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis SQS_PSY PF00494.14 KOS19371.1 - 0.04 13.2 1.6 0.52 9.5 0.1 2.1 1 1 1 2 2 2 0 Squalene/phytoene synthase WD40 PF00400.27 KOS19373.1 - 3.4e-53 175.7 18.9 2.9e-11 42.7 0.3 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KOS19373.1 - 2.5e-07 29.2 5.7 0.0081 14.3 0.2 4.0 2 2 1 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 KOS19373.1 - 8.4e-07 28.8 0.0 0.00022 21.0 0.0 3.2 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KOS19373.1 - 0.0025 16.1 0.0 0.03 12.6 0.0 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KOS19373.1 - 0.017 13.8 0.0 2.7 6.6 0.0 3.1 1 1 1 3 3 3 0 Nup133 N terminal like GPI-anchored PF10342.4 KOS19374.1 - 1.9e-17 63.4 1.2 1.9e-17 63.4 0.8 2.7 3 1 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KOS19374.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) THF_DHG_CYH PF00763.18 KOS19375.1 - 3.4e-19 68.9 0.1 5e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 KOS19375.1 - 2.7e-13 49.2 0.1 3e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short PF00106.20 KOS19376.1 - 3.3e-09 36.8 0.7 3.7e-09 36.7 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS19376.1 - 2.1e-06 27.5 0.2 2.5e-06 27.2 0.2 1.0 1 0 0 1 1 1 1 KR domain PDZ PF00595.19 KOS19376.1 - 0.039 14.1 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Pkinase PF00069.20 KOS19377.1 - 5.9e-66 222.2 0.0 9.6e-66 221.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19377.1 - 5.1e-36 124.0 0.0 8.1e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS19377.1 - 5.7e-07 28.7 0.0 2.3e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KOS19377.1 - 0.004 16.9 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KOS19377.1 - 0.051 12.4 0.0 0.098 11.4 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 dCMP_cyt_deam_1 PF00383.17 KOS19378.1 - 2.1e-09 36.9 2.2 2.1e-07 30.5 1.5 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 KOS19378.1 - 0.004 16.5 3.5 0.15 11.3 0.2 2.2 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_2 PF08211.6 KOS19378.1 - 0.064 13.2 0.8 0.064 13.2 0.5 2.9 2 1 1 3 3 3 0 Cytidine and deoxycytidylate deaminase zinc-binding region PI-PLC-X PF00388.14 KOS19381.1 - 2e-59 199.2 0.0 2.8e-59 198.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KOS19381.1 - 9e-34 115.9 0.0 9e-34 115.9 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KOS19381.1 - 0.006 16.5 3.7 0.013 15.5 0.0 2.8 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like Trypan_PARP PF05887.6 KOS19381.1 - 0.13 12.0 11.5 0.29 10.9 8.0 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Spore_coat_CotO PF14153.1 KOS19381.1 - 2.7 7.4 12.3 4.5 6.6 8.5 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Ycf1 PF05758.7 KOS19381.1 - 8.8 3.8 6.7 12 3.4 4.6 1.1 1 0 0 1 1 1 0 Ycf1 Zn_clus PF00172.13 KOS19384.1 - 0.00024 20.9 13.0 0.00042 20.1 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Urb2 PF10441.4 KOS19385.1 - 3.2e-50 170.7 0.2 4.3e-49 167.1 0.0 2.6 3 0 0 3 3 3 1 Urb2/Npa2 family adh_short PF00106.20 KOS19386.1 - 1.8e-29 102.8 0.0 2.6e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS19386.1 - 5.4e-16 58.7 0.0 9.2e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KOS19386.1 - 1.4e-09 38.0 0.0 2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KOS19386.1 - 4.3e-05 23.5 0.3 0.00012 22.0 0.2 1.9 2 1 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KOS19386.1 - 0.0027 17.4 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 KOS19386.1 - 0.021 14.4 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.13 KOS19386.1 - 0.029 14.0 0.1 0.056 13.1 0.0 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KOS19386.1 - 0.047 13.5 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ATP-synt_ab PF00006.20 KOS19386.1 - 0.063 12.7 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ETF PF01012.16 KOS19386.1 - 0.064 12.9 0.2 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein domain NAD_binding_7 PF13241.1 KOS19386.1 - 0.094 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 KOS19386.1 - 0.22 11.6 0.7 0.34 10.9 0.1 1.7 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NRDE-2 PF08424.5 KOS19387.1 - 2.7e-79 266.3 0.1 4.4e-76 255.8 0.1 2.3 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_19 PF14559.1 KOS19387.1 - 0.00046 20.4 5.0 0.14 12.5 0.2 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KOS19387.1 - 0.0073 16.8 13.1 4 8.3 0.4 7.5 7 2 2 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 KOS19387.1 - 0.022 15.4 3.5 0.022 15.4 2.4 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.1 KOS19388.1 - 0.0042 17.3 9.5 0.046 14.0 0.1 3.0 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KOS19388.1 - 0.021 15.1 1.6 2.2 8.8 0.0 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Med18 PF09637.5 KOS19390.1 - 5.7e-07 29.3 0.0 6.4e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Med18 protein Proteasome PF00227.21 KOS19391.1 - 4.9e-49 166.1 0.2 5.9e-49 165.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 KOS19391.1 - 0.0021 17.2 0.1 0.0029 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF554) DUF3222 PF11519.3 KOS19391.1 - 0.11 12.4 0.4 6.4 6.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) Peptidase_M22 PF00814.20 KOS19392.1 - 2.2e-42 145.3 0.0 1.2e-19 70.8 0.3 3.1 2 1 0 2 2 2 2 Glycoprotease family MFS_2 PF13347.1 KOS19394.1 - 1.8e-07 29.9 5.1 1.8e-07 29.9 3.6 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein DUF2417 PF10329.4 KOS19394.1 - 0.086 12.2 0.2 0.61 9.4 0.0 2.2 2 0 0 2 2 2 0 Region of unknown function (DUF2417) S1FA PF04689.8 KOS19394.1 - 3.5 7.5 3.9 38 4.2 0.0 3.1 3 0 0 3 3 3 0 DNA binding protein S1FA Ribosomal_60s PF00428.14 KOS19394.1 - 3.9 7.9 7.9 2 8.9 3.8 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein MAPEG PF01124.13 KOS19395.1 - 5.5e-15 55.1 5.2 7.9e-15 54.6 3.6 1.2 1 1 0 1 1 1 1 MAPEG family DUF533 PF04391.7 KOS19395.1 - 0.056 12.8 0.3 0.11 11.8 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF533) Glyco_transf_34 PF05637.7 KOS19397.1 - 7.5e-64 215.4 0.9 1.1e-63 215.0 0.6 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_hydro_16 PF00722.16 KOS19398.1 - 6.1e-12 45.2 0.3 4.1e-11 42.4 0.2 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Adeno_shaft PF00608.12 KOS19398.1 - 0.021 14.4 0.7 0.069 12.7 0.3 2.0 2 0 0 2 2 2 0 Adenoviral fibre protein (repeat/shaft region) EXOSC1 PF10447.4 KOS19401.1 - 3.8e-26 90.8 2.1 6.2e-26 90.1 1.4 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KOS19401.1 - 6.5e-14 50.9 0.2 1.4e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region ABC_membrane PF00664.18 KOS19402.1 - 1.1e-46 159.4 38.1 2e-27 96.3 12.4 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 KOS19402.1 - 2.2e-45 154.3 0.1 6.5e-26 91.2 0.0 2.9 3 0 0 3 3 2 2 ABC transporter Miro PF08477.8 KOS19402.1 - 1.3e-05 25.6 0.6 0.058 13.9 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KOS19402.1 - 1.6e-05 24.3 0.6 0.057 12.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KOS19402.1 - 1.8e-05 24.7 1.5 0.18 11.7 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KOS19402.1 - 5.3e-05 23.2 0.2 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KOS19402.1 - 0.00013 21.2 0.7 0.12 11.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 KOS19402.1 - 0.00015 21.8 10.1 1.5 8.7 0.8 4.6 4 1 0 4 4 4 2 AAA domain AAA_17 PF13207.1 KOS19402.1 - 0.0006 20.6 0.5 1.6 9.5 0.3 3.3 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KOS19402.1 - 0.00084 18.4 0.1 0.23 10.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin ArgK PF03308.11 KOS19402.1 - 0.0015 17.4 2.1 0.52 9.0 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_30 PF13604.1 KOS19402.1 - 0.0031 17.0 2.0 1 8.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KOS19402.1 - 0.0034 16.6 4.7 1.3 8.1 0.1 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 KOS19402.1 - 0.0041 16.9 4.7 0.17 11.6 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 KOS19402.1 - 0.0044 17.1 0.1 2.2 8.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KOS19402.1 - 0.0049 16.2 0.1 0.36 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KOS19402.1 - 0.0066 16.2 3.4 0.099 12.4 0.5 2.6 2 0 0 2 2 2 1 Dynamin family AAA_10 PF12846.2 KOS19402.1 - 0.0086 15.5 1.0 3.4 7.0 0.3 2.5 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 KOS19402.1 - 0.016 14.6 0.1 4.3 6.7 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 KOS19402.1 - 0.026 13.1 0.4 2.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 KOS19402.1 - 0.09 12.4 1.7 5.1 6.7 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KOS19402.1 - 0.094 13.0 6.0 4.5 7.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KOS19402.1 - 1 9.6 3.6 16 5.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain TruB_N PF01509.13 KOS19403.1 - 9.1e-46 155.7 0.0 3.7e-45 153.7 0.0 1.9 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DUF4612 PF15389.1 KOS19403.1 - 2.1 8.9 9.7 0.12 12.9 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) Sec2p PF06428.6 KOS19404.1 - 7.7e-11 41.7 6.1 4.6e-10 39.2 4.6 1.9 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p CDC27 PF09507.5 KOS19404.1 - 0.047 12.9 7.5 0.063 12.4 5.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CAP_N PF01213.14 KOS19404.1 - 0.071 12.3 9.1 0.28 10.4 3.3 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF2360 PF10152.4 KOS19404.1 - 0.13 12.5 13.4 0.27 11.5 8.0 2.4 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) HSBP1 PF06825.7 KOS19404.1 - 0.14 11.7 0.4 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 Heat shock factor binding protein 1 SlyX PF04102.7 KOS19404.1 - 0.34 11.2 15.9 1 9.8 0.0 3.9 3 1 1 4 4 3 0 SlyX Mito_fiss_reg PF05308.6 KOS19404.1 - 0.44 9.8 12.9 0.17 11.2 7.2 1.7 1 1 0 1 1 1 0 Mitochondrial fission regulator Hamartin PF04388.7 KOS19404.1 - 0.53 8.8 13.8 0.65 8.6 9.6 1.2 1 0 0 1 1 1 0 Hamartin protein CHDCT2 PF08074.6 KOS19404.1 - 1.2 8.8 5.7 2.4 7.8 3.9 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain DUF605 PF04652.11 KOS19404.1 - 1.5 8.1 12.7 1.9 7.7 8.8 1.1 1 0 0 1 1 1 0 Vta1 like Jnk-SapK_ap_N PF09744.4 KOS19404.1 - 2.3 8.1 12.7 3 7.8 8.0 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 TFIIA PF03153.8 KOS19404.1 - 4 7.2 6.9 4.9 6.9 4.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.14 KOS19404.1 - 5.5 4.7 5.6 8.5 4.0 3.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MIF4G_like PF09088.6 KOS19405.1 - 4e-79 264.5 0.1 6.1e-79 263.8 0.1 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KOS19405.1 - 3.8e-42 144.2 0.0 5.5e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 MIF4G like 6PF2K PF01591.13 KOS19407.1 - 7.5e-57 191.9 0.0 1.4e-56 191.0 0.0 1.4 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KOS19407.1 - 8.7e-22 77.9 0.2 1.4e-21 77.2 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 KOS19407.1 - 0.0022 18.8 0.1 0.032 15.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS19407.1 - 0.0052 16.6 0.0 0.016 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KOS19407.1 - 0.055 12.6 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 IstB_IS21 PF01695.12 KOS19407.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Pkinase PF00069.20 KOS19408.1 - 2.5e-37 128.4 0.1 1.6e-32 112.6 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19408.1 - 6.2e-11 41.8 0.0 9.5e-09 34.6 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KOS19408.1 - 2.8e-05 23.2 0.0 6.3e-05 22.0 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KOS19408.1 - 0.0041 16.8 0.0 0.0081 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KOS19408.1 - 0.064 12.0 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 KOS19408.1 - 0.093 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase UPF0220 PF05255.6 KOS19410.1 - 2.7e-64 215.3 2.6 3e-64 215.2 1.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) EMP24_GP25L PF01105.19 KOS19411.1 - 5.6e-43 146.7 0.7 6.4e-43 146.6 0.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Peptidase_C36 PF05415.6 KOS19411.1 - 0.057 13.3 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase MMtag PF10159.4 KOS19412.1 - 1.6e-29 101.7 6.9 5e-29 100.1 4.8 1.7 1 1 0 1 1 1 1 Kinase phosphorylation protein Mito_carr PF00153.22 KOS19413.1 - 1.3e-14 53.6 2.7 0.0002 21.0 0.1 5.3 5 0 0 5 5 5 5 Mitochondrial carrier protein Serglycin PF04360.7 KOS19414.1 - 0.0021 17.8 0.4 0.0021 17.8 0.2 2.7 2 0 0 2 2 2 1 Serglycin T2SM PF04612.7 KOS19414.1 - 0.0093 15.7 2.2 0.013 15.2 0.1 2.2 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein M DUF1183 PF06682.7 KOS19414.1 - 2.1 7.8 16.2 0.025 14.2 2.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1183) DUF846 PF05832.7 KOS19415.1 - 1.4e-50 170.6 5.3 1.8e-50 170.3 3.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4191 PF13829.1 KOS19415.1 - 0.11 11.5 5.4 1 8.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF3329 PF11808.3 KOS19415.1 - 5.4 7.1 9.1 0.29 11.2 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) CbiQ PF02361.11 KOS19415.1 - 9.8 5.6 12.4 36 3.8 8.7 1.7 1 1 0 1 1 1 0 Cobalt transport protein Fcf1 PF04900.7 KOS19416.1 - 2e-24 85.5 0.0 4.9e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 Fcf1 SbcCD_C PF13558.1 KOS19416.1 - 0.077 12.9 0.2 0.3 11.0 0.1 2.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF726 PF05277.7 KOS19417.1 - 4e-127 423.8 2.7 5.4e-127 423.4 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 KOS19417.1 - 0.057 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Pkinase PF00069.20 KOS19418.1 - 4.1e-66 222.7 0.0 8.1e-66 221.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19418.1 - 3.2e-30 105.0 0.0 6.9e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KOS19418.1 - 4.9e-08 32.9 0.0 1.9e-07 31.0 0.0 2.1 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KOS19418.1 - 0.004 16.1 0.0 0.032 13.1 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KOS19418.1 - 0.0081 15.2 0.1 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KOS19418.1 - 0.32 9.7 0.0 0.55 8.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PP2C_2 PF13672.1 KOS19419.1 - 1.5e-06 27.7 0.1 2.2e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KOS19419.1 - 0.022 14.4 0.1 0.14 11.8 0.0 2.3 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DUF4266 PF14086.1 KOS19419.1 - 2.4 8.7 7.2 9.2 6.8 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) Inhibitor_I53 PF11714.3 KOS19420.1 - 0.0043 17.0 0.6 0.021 14.7 0.4 2.2 1 0 0 1 1 1 1 Thrombin inhibitor Madanin Mfp-3 PF04202.8 KOS19420.1 - 2.3 8.4 6.9 5.8 7.1 4.4 1.9 2 0 0 2 2 2 0 Foot protein 3 DZR PF12773.2 KOS19420.1 - 5.2 6.9 8.4 82 3.1 5.9 2.6 1 1 1 2 2 2 0 Double zinc ribbon HpcH_HpaI PF03328.9 KOS19421.1 - 6.7e-42 142.8 0.1 7.6e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KOS19421.1 - 3.2e-06 26.2 0.0 0.009 14.8 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PEP-utilizers_C PF02896.13 KOS19421.1 - 0.12 11.1 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Malate_synthase PF01274.17 KOS19421.1 - 0.13 10.2 0.0 0.26 9.2 0.0 1.4 1 1 1 2 2 2 0 Malate synthase RRM_1 PF00076.17 KOS19422.1 - 3e-20 71.5 0.0 4.5e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS19422.1 - 9.4e-12 44.7 0.0 1.5e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS19422.1 - 5.2e-05 23.0 0.0 7.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KRTAP PF11759.3 KOS19422.1 - 0.43 10.8 6.9 0.85 9.9 4.8 1.6 1 1 0 1 1 1 0 Keratin-associated matrix DUF3984 PF13136.1 KOS19423.1 - 2.1e-69 234.2 16.2 2.8e-69 233.8 11.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) MdcG PF10620.4 KOS19423.1 - 0.035 13.6 2.4 0.06 12.8 1.7 1.3 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG YL1 PF05764.8 KOS19423.1 - 6.6 6.2 9.7 0.48 10.0 1.9 2.2 2 0 0 2 2 2 0 YL1 nuclear protein DUF1620 PF07774.8 KOS19424.1 - 8.5e-65 218.0 0.0 1.3e-64 217.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KOS19424.1 - 4e-17 62.4 5.9 2.8e-13 49.8 1.1 2.6 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.16 KOS19424.1 - 2.1e-06 26.9 0.5 0.0078 15.6 0.0 4.8 5 0 0 5 5 5 1 PQQ enzyme repeat ATP_bind_3 PF01171.15 KOS19427.1 - 2.1e-34 118.6 3.6 9.1e-23 80.6 0.0 2.8 3 0 0 3 3 3 2 PP-loop family bZIP_1 PF00170.16 KOS19428.1 - 1.6e-07 31.1 7.0 3.2e-07 30.2 4.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KOS19428.1 - 3.7e-06 26.6 3.7 3.7e-06 26.6 2.6 1.9 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 KOS19428.1 - 0.0032 17.7 2.0 0.0032 17.7 1.4 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor SCIMP PF15050.1 KOS19428.1 - 0.088 12.7 0.1 0.088 12.7 0.1 2.8 2 1 1 3 3 3 0 SCIMP protein PAT1 PF09770.4 KOS19428.1 - 0.89 7.7 29.7 1.1 7.4 20.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 KOS19428.1 - 8.1 5.7 33.0 12 5.2 22.8 1.2 1 0 0 1 1 1 0 Vta1 like Cyclin_N PF00134.18 KOS19430.1 - 2.6e-11 43.1 0.1 5.5e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Turandot PF07240.6 KOS19430.1 - 0.083 12.3 0.2 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot YliH PF10799.3 KOS19430.1 - 0.12 12.0 0.8 0.34 10.6 0.3 2.0 1 1 1 2 2 2 0 Biofilm formation protein (YliH/bssR) Mito_carr PF00153.22 KOS19431.1 - 2.9e-68 225.6 4.8 4.1e-25 87.3 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KOS19431.1 - 9.1e-24 83.3 7.3 2.9e-14 52.9 2.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KOS19431.1 - 1.4e-21 74.0 9.7 1e-07 30.7 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.1 KOS19431.1 - 7e-18 63.0 12.6 5.9e-06 25.3 1.4 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KOS19431.1 - 1.5e-16 58.6 9.9 6.6e-06 25.5 0.2 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KOS19431.1 - 1.8e-15 56.2 7.5 7.7e-08 31.8 0.6 3.3 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KOS19431.1 - 1.4e-07 31.5 0.1 7.3e-06 25.9 0.1 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 KOS19431.1 - 0.024 14.2 0.5 9.3 6.0 0.0 2.9 2 1 1 3 3 3 0 EF hand EF-hand_4 PF12763.2 KOS19431.1 - 0.073 12.8 1.9 1.3 8.8 0.3 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Pex19 PF04614.7 KOS19431.1 - 0.18 11.3 0.1 0.29 10.7 0.1 1.2 1 0 0 1 1 1 0 Pex19 protein family DUF4098 PF13345.1 KOS19432.1 - 5.1e-06 26.3 0.2 0.97 9.4 0.0 4.4 4 1 0 4 4 4 2 Domain of unknown function (DUF4098) DUF4452 PF14618.1 KOS19434.1 - 2e-70 235.8 12.6 2.5e-70 235.5 8.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) DnaJ PF00226.26 KOS19435.1 - 4.6e-07 29.4 0.0 6.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KOS19435.1 - 1.4e-06 28.1 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Pam16 DUF3918 PF13056.1 KOS19435.1 - 0.18 11.1 0.9 0.58 9.5 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Ku_N PF03731.10 KOS19437.1 - 3.6e-19 69.0 0.0 6.3e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 KOS19437.1 - 2.2e-16 59.8 0.0 4.3e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.11 KOS19437.1 - 3.2e-16 59.3 0.0 2e-15 56.7 0.0 2.0 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain VWA_2 PF13519.1 KOS19437.1 - 1.6e-05 25.0 0.0 3.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KOS19437.1 - 0.056 13.1 0.0 0.53 9.9 0.0 2.1 1 1 0 1 1 1 0 von Willebrand factor type A domain DUF4149 PF13664.1 KOS19438.1 - 2.5e-24 85.2 1.5 2.5e-24 85.2 1.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) E1-E2_ATPase PF00122.15 KOS19439.1 - 3.7e-53 179.9 1.8 7.7e-53 178.8 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KOS19439.1 - 3.9e-46 158.1 2.9 1e-45 156.8 2.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KOS19439.1 - 8.2e-42 141.1 0.1 2.5e-11 43.5 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KOS19439.1 - 1.9e-13 51.0 0.0 5e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KOS19439.1 - 2.8e-06 27.1 1.6 4.7e-05 23.1 0.7 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase FA_desaturase PF00487.19 KOS19441.1 - 0.0077 15.6 0.1 0.0077 15.6 0.1 3.3 2 1 1 3 3 3 1 Fatty acid desaturase zf-BED PF02892.10 KOS19442.1 - 0.016 14.9 2.3 0.034 13.9 1.6 1.4 1 0 0 1 1 1 0 BED zinc finger zf-C2H2 PF00096.21 KOS19442.1 - 0.044 14.1 2.6 0.044 14.1 1.8 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS19442.1 - 0.37 11.2 2.3 1.3 9.5 1.6 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger RGS PF00615.14 KOS19443.1 - 9.2e-11 41.8 0.0 4.3e-09 36.4 0.0 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF2413 PF10310.4 KOS19443.1 - 0.094 11.5 0.2 0.16 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) O-antigen_lig PF13425.1 KOS19443.1 - 5.5 6.9 8.8 12 5.8 6.1 1.6 1 1 0 1 1 1 0 O-antigen ligase like membrane protein PCI PF01399.22 KOS19444.1 - 2.1e-05 24.7 0.0 3.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PCI domain Cation_efflux PF01545.16 KOS19445.1 - 5e-77 258.7 9.0 2.3e-76 256.6 6.3 1.8 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.17 KOS19445.1 - 3.8e-07 29.4 10.4 3.8e-07 29.4 7.2 2.3 2 0 0 2 2 2 1 ZIP Zinc transporter Cyclin_N PF00134.18 KOS19447.1 - 1.8e-35 121.3 0.1 3.2e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KOS19447.1 - 2.5e-13 49.9 0.1 7e-13 48.5 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain 2-Hacid_dh_C PF02826.14 KOS19449.1 - 1.1e-50 171.2 0.0 1.7e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KOS19449.1 - 2.6e-18 65.7 0.0 3.4e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KOS19449.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KOS19449.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Pkinase PF00069.20 KOS19450.1 - 1.9e-39 135.3 0.0 2.9e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19450.1 - 2e-29 102.4 0.0 2.8e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS19450.1 - 4.4e-05 23.3 0.2 0.4 10.3 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KOS19450.1 - 0.0028 16.7 0.0 0.0051 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KOS19450.1 - 0.017 14.0 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like HeLo PF14479.1 KOS19452.1 - 3.4e-44 151.1 0.8 7.2e-44 150.0 0.6 1.6 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.20 KOS19452.1 - 0.027 13.6 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Zn_clus PF00172.13 KOS19453.1 - 4.1e-10 39.4 7.0 7.9e-10 38.4 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KOS19453.1 - 3.6e-09 35.8 1.4 2.1e-08 33.3 0.3 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain Endonuc-PvuII PF09225.5 KOS19453.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease PvuII ABC2_membrane PF01061.19 KOS19454.1 - 9.4e-33 113.1 22.0 1.3e-32 112.7 15.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KOS19454.1 - 3.1e-25 89.0 0.1 4.8e-25 88.4 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KOS19454.1 - 6.2e-07 29.6 0.1 0.022 14.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 KOS19454.1 - 7e-06 25.3 14.0 1.2e-05 24.4 9.7 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.14 KOS19454.1 - 1.4e-05 24.3 0.1 2.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 KOS19454.1 - 0.00013 21.6 0.0 0.0069 16.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 KOS19454.1 - 0.00013 21.3 0.0 0.0052 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KOS19454.1 - 0.0002 21.5 0.0 0.00082 19.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KOS19454.1 - 0.00044 19.4 0.0 0.00076 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KOS19454.1 - 0.00045 20.2 0.1 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KOS19454.1 - 0.0013 19.5 0.0 0.0026 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KOS19454.1 - 0.0017 18.5 0.1 0.016 15.3 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KOS19454.1 - 0.0033 17.3 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KOS19454.1 - 0.0053 15.8 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 KOS19454.1 - 0.0075 15.7 0.4 0.016 14.6 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KOS19454.1 - 0.0081 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KOS19454.1 - 0.015 14.8 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KOS19454.1 - 0.017 15.4 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KOS19454.1 - 0.019 14.8 0.0 0.068 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 KOS19454.1 - 0.024 13.3 0.0 0.036 12.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 KOS19454.1 - 0.026 14.4 0.0 0.068 13.1 0.0 1.7 2 0 0 2 2 1 0 50S ribosome-binding GTPase AAA_5 PF07728.9 KOS19454.1 - 0.037 13.7 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 KOS19454.1 - 0.039 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PDR_CDR PF06422.7 KOS19454.1 - 0.077 12.6 1.5 0.096 12.3 0.0 2.0 2 0 0 2 2 1 0 CDR ABC transporter Arch_ATPase PF01637.13 KOS19454.1 - 0.082 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 KOS19454.1 - 0.085 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 KOS19454.1 - 0.097 12.5 0.0 0.53 10.2 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 KOS19454.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase O-antigen_lig PF13425.1 KOS19454.1 - 0.18 11.8 8.2 0.25 11.3 3.1 2.3 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Cytochrom_B561 PF03188.11 KOS19455.1 - 3.6e-07 30.0 10.4 3.6e-07 30.0 7.2 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KOS19455.1 - 0.00029 20.3 6.7 0.00029 20.3 4.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF668 PF05003.7 KOS19455.1 - 0.0058 16.8 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF668) HAD_2 PF13419.1 KOS19456.1 - 4e-28 98.8 0.1 7.3e-28 97.9 0.1 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS19456.1 - 0.042 14.2 0.0 0.094 13.1 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase bZIP_1 PF00170.16 KOS19457.1 - 2.8e-05 23.9 4.3 2.8e-05 23.9 3.0 2.3 3 0 0 3 3 3 1 bZIP transcription factor DUF4647 PF15504.1 KOS19457.1 - 0.0054 15.6 9.5 0.0054 15.6 6.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4647) Band_3_cyto PF07565.8 KOS19457.1 - 0.4 10.1 6.7 0.8 9.1 4.7 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ndc1_Nup PF09531.5 KOS19457.1 - 0.4 9.0 6.5 0.57 8.5 4.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAGA-Tad1 PF12767.2 KOS19457.1 - 0.6 9.7 16.8 0.11 12.1 7.9 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Ctr PF04145.10 KOS19457.1 - 0.73 9.8 2.3 2 8.4 1.6 1.8 1 0 0 1 1 1 0 Ctr copper transporter family PAT1 PF09770.4 KOS19457.1 - 1 7.5 49.2 0.21 9.7 25.7 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 KOS19457.1 - 1.6 6.2 9.5 2.2 5.8 6.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 KOS19457.1 - 1.6 7.6 6.8 2.5 6.9 4.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4175 PF13779.1 KOS19457.1 - 2.5 5.7 33.4 0.31 8.6 19.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF2052 PF09747.4 KOS19457.1 - 9.1 6.1 18.4 0.46 10.3 8.8 1.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) VWA_3 PF13768.1 KOS19458.1 - 1.8e-24 86.1 0.0 4e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KOS19458.1 - 6.2e-13 49.2 0.0 1.4e-12 48.0 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 KOS19458.1 - 3.5e-09 36.6 0.0 6.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KOS19458.1 - 2.1e-06 27.0 0.0 3.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 KOS19458.1 - 0.036 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus WWE PF02825.15 KOS19458.1 - 0.091 12.1 0.5 0.42 10.0 0.0 2.3 3 0 0 3 3 3 0 WWE domain Sugar_tr PF00083.19 KOS19459.1 - 1.2e-83 281.1 22.4 1.4e-83 280.9 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS19459.1 - 5.2e-17 61.5 32.2 2.2e-15 56.2 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KOS19459.1 - 0.0006 18.3 28.8 0.002 16.6 3.7 3.4 2 2 2 4 4 4 2 MFS/sugar transport protein Brr6_like_C_C PF10104.4 KOS19460.1 - 2.1e-33 114.6 3.4 3.4e-33 114.0 2.4 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Med26 PF08711.6 KOS19461.1 - 2.6e-12 46.0 0.0 4.5e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Sox_C_TAD PF12067.3 KOS19461.1 - 0.17 12.0 0.6 0.33 11.1 0.4 1.3 1 0 0 1 1 1 0 Sox C-terminal transactivation domain RNA_pol_Rpb1_5 PF04998.12 KOS19462.1 - 1.7e-87 293.2 0.0 2.8e-87 292.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KOS19462.1 - 2.3e-83 280.2 0.0 3.8e-83 279.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KOS19462.1 - 2.2e-67 226.1 0.0 7.5e-67 224.4 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KOS19462.1 - 4e-34 117.6 0.0 1.2e-33 116.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KOS19462.1 - 1.9e-30 104.7 0.1 6.9e-30 102.9 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Pyr_redox_3 PF13738.1 KOS19463.1 - 6.7e-25 88.3 0.0 7.6e-24 84.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KOS19463.1 - 2.3e-11 43.2 0.1 7.1e-09 35.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KOS19463.1 - 2.3e-11 42.5 0.0 8.4e-09 34.1 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KOS19463.1 - 5.2e-10 39.5 0.0 3.7e-07 30.2 0.0 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KOS19463.1 - 1.9e-06 27.1 0.0 0.0013 17.8 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 KOS19463.1 - 3.8e-06 26.8 0.0 0.00013 21.9 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KOS19463.1 - 8.3e-06 26.1 0.4 0.031 14.6 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KOS19463.1 - 0.00026 20.1 0.1 0.018 14.1 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KOS19463.1 - 0.0012 18.9 0.4 2 8.5 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KOS19463.1 - 0.0015 18.5 0.2 0.12 12.3 0.0 3.1 3 1 0 3 3 3 1 TrkA-N domain SnoaL_2 PF12680.2 KOS19463.1 - 0.0016 18.7 1.6 0.078 13.3 0.0 2.7 2 0 0 2 2 2 1 SnoaL-like domain DAO PF01266.19 KOS19463.1 - 0.002 17.1 1.0 0.19 10.5 0.0 3.4 3 1 0 4 4 4 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KOS19463.1 - 0.004 16.8 0.7 1.2 8.7 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KOS19463.1 - 0.0044 15.9 1.9 0.052 12.3 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KOS19463.1 - 0.006 15.0 0.1 0.019 13.4 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein IlvN PF07991.7 KOS19463.1 - 0.0067 15.8 1.4 0.14 11.4 0.2 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 KOS19463.1 - 0.007 16.6 0.0 0.32 11.2 0.1 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding F420_oxidored PF03807.12 KOS19463.1 - 0.017 15.5 0.6 0.5 10.8 0.2 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KOS19463.1 - 0.017 14.5 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KOS19463.1 - 0.02 14.6 1.2 5.3 6.7 0.1 3.0 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 KOS19463.1 - 0.034 13.0 0.1 0.12 11.2 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_10 PF13460.1 KOS19463.1 - 0.063 13.2 0.1 5 7.0 0.0 2.6 2 0 0 2 2 2 0 NADH(P)-binding ThiF PF00899.16 KOS19463.1 - 0.07 12.9 0.2 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 ThiF family GIDA PF01134.17 KOS19463.1 - 0.16 10.8 0.8 0.82 8.4 0.1 2.2 3 0 0 3 3 3 0 Glucose inhibited division protein A SnoaL_3 PF13474.1 KOS19463.1 - 0.24 11.4 1.2 2 8.4 0.3 2.7 2 1 0 2 2 2 0 SnoaL-like domain PUL PF08324.6 KOS19465.1 - 6.3e-44 149.7 0.0 8.5e-44 149.3 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 KOS19465.1 - 1.2e-42 144.5 0.2 2.2e-42 143.7 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KOS19465.1 - 2.5e-39 131.7 12.6 2.7e-08 33.3 0.2 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 KOS19465.1 - 0.0079 15.9 0.0 3.2 7.5 0.0 3.7 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 KOS19466.1 - 4.3e-18 64.4 0.8 8.3e-12 44.5 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat tRNA-synt_2d PF01409.15 KOS19467.1 - 2.8e-83 278.9 0.0 3.9e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KOS19467.1 - 6.5e-06 25.1 0.6 0.00028 19.7 0.1 2.8 2 1 1 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KOS19467.1 - 0.00033 20.2 0.1 0.0012 18.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Spore_coat_CotO PF14153.1 KOS19468.1 - 1.1e-08 34.6 16.7 1.4e-08 34.4 11.6 1.2 1 0 0 1 1 1 1 Spore coat protein CotO SAPS PF04499.10 KOS19468.1 - 0.0002 20.1 10.5 0.00023 19.9 7.3 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein SPX PF03105.14 KOS19468.1 - 0.00041 20.2 6.3 0.00045 20.0 4.4 1.1 1 0 0 1 1 1 1 SPX domain SDA1 PF05285.7 KOS19468.1 - 0.22 10.7 36.4 0.3 10.3 25.2 1.1 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.6 KOS19468.1 - 0.24 9.2 9.3 0.31 8.8 6.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-T PF15511.1 KOS19468.1 - 0.68 9.1 31.3 0.99 8.5 21.7 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T MIP-T3 PF10243.4 KOS19468.1 - 0.87 7.9 41.8 1.2 7.5 29.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 KOS19468.1 - 0.88 7.4 43.4 1.1 7.1 30.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4045 PF13254.1 KOS19468.1 - 1.3 8.2 21.4 2 7.6 14.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC45 PF02724.9 KOS19468.1 - 1.8 6.5 32.7 2.3 6.1 22.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Otopetrin PF03189.8 KOS19468.1 - 2.5 7.0 3.3 3 6.7 2.3 1.1 1 0 0 1 1 1 0 Otopetrin PLRV_ORF5 PF01690.12 KOS19468.1 - 4.3 6.3 21.3 5.8 5.9 14.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Daxx PF03344.10 KOS19468.1 - 4.6 5.6 44.9 6.4 5.1 31.1 1.1 1 0 0 1 1 1 0 Daxx Family Tim54 PF11711.3 KOS19468.1 - 8.8 4.8 22.3 17 3.9 15.5 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Metallophos PF00149.23 KOS19469.1 - 0.018 14.4 4.9 0.04 13.3 3.4 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 KOS19469.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain DUF4185 PF13810.1 KOS19470.1 - 9.3e-07 28.0 1.5 1.4e-06 27.4 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) DUF1776 PF08643.5 KOS19471.1 - 1.2e-103 346.3 0.0 1.5e-103 346.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) HATPase_c PF02518.21 KOS19472.1 - 1.6e-29 101.8 0.1 2.8e-29 101.0 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KOS19472.1 - 6.7e-23 80.8 0.3 2.2e-22 79.1 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KOS19472.1 - 2.4e-22 78.6 0.1 6e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 KOS19472.1 - 5.2e-20 71.7 0.0 2.3e-14 53.6 0.0 3.6 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.6 KOS19472.1 - 5.2e-17 61.7 0.2 2.2e-16 59.7 0.2 2.2 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 KOS19472.1 - 2e-16 59.7 0.0 3.3e-10 39.7 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KOS19472.1 - 3.7e-12 46.2 0.5 4.5e-08 33.1 0.0 3.9 3 1 0 3 3 3 2 PAS fold PAS_8 PF13188.1 KOS19472.1 - 7.7e-09 35.1 0.0 3.2e-05 23.6 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_11 PF14598.1 KOS19472.1 - 0.0021 17.9 0.0 0.0048 16.8 0.0 1.6 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.1 KOS19472.1 - 0.049 13.2 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Amidase PF01425.16 KOS19473.1 - 4.5e-88 296.0 0.0 6.9e-88 295.4 0.0 1.3 1 0 0 1 1 1 1 Amidase PapJ PF14855.1 KOS19474.1 - 0.047 13.1 0.1 0.069 12.6 0.0 1.1 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone SNARE PF05739.14 KOS19475.1 - 1.5e-10 40.6 6.6 1.5e-10 40.6 4.6 2.6 2 1 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KOS19475.1 - 4.7e-05 23.5 1.5 4.7e-05 23.5 1.1 2.4 2 0 0 2 2 2 1 Syntaxin ODV-E18 PF10717.4 KOS19475.1 - 0.0039 16.5 0.7 0.016 14.6 0.0 2.1 2 0 0 2 2 2 1 Occlusion-derived virus envelope protein ODV-E18 DUF912 PF06024.7 KOS19475.1 - 0.0043 17.0 1.0 0.0069 16.4 0.1 1.8 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1510 PF07423.6 KOS19475.1 - 0.0076 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) ASFV_J13L PF05568.6 KOS19475.1 - 0.012 15.1 0.2 0.025 14.1 0.1 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein Rifin_STEVOR PF02009.11 KOS19475.1 - 0.021 14.4 8.8 0.051 13.2 5.9 1.9 1 1 0 1 1 1 0 Rifin/stevor family CbiN PF02553.10 KOS19475.1 - 0.064 13.2 0.1 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Cobalt transport protein component CbiN HTH_Tnp_IS1 PF12759.2 KOS19475.1 - 0.078 12.4 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 InsA C-terminal domain Spc97_Spc98 PF04130.8 KOS19475.1 - 0.082 11.2 0.1 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Spc97 / Spc98 family Mid2 PF04478.7 KOS19475.1 - 0.12 11.8 3.9 0.28 10.6 2.7 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor ROF PF07073.7 KOS19475.1 - 0.55 10.2 4.4 8.2 6.5 0.7 3.1 3 0 0 3 3 3 0 Modulator of Rho-dependent transcription termination (ROF) Tropomyosin_1 PF12718.2 KOS19475.1 - 0.72 9.6 10.5 2.8 7.8 2.4 3.1 3 0 0 3 3 3 0 Tropomyosin like zf-CCCH PF00642.19 KOS19476.1 - 7e-24 83.0 32.8 3.3e-08 33.0 0.4 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KOS19476.1 - 0.024 14.6 0.3 0.024 14.6 0.2 5.1 5 1 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type DUF2849 PF11011.3 KOS19476.1 - 1.6 9.0 5.2 3.5 7.9 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) FokI_N PF02981.10 KOS19477.1 - 0.12 11.9 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain Kei1 PF08552.6 KOS19478.1 - 0.022 14.3 0.0 0.036 13.7 0.0 1.4 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 NAD_binding_6 PF08030.7 KOS19479.1 - 7.6e-24 84.3 0.0 1.2e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KOS19479.1 - 8.1e-23 80.2 0.0 1.6e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KOS19479.1 - 6.7e-19 68.2 8.3 6.7e-19 68.2 5.7 2.5 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KOS19479.1 - 0.0011 19.0 0.0 0.0026 17.8 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KOS19479.1 - 0.08 13.5 0.0 2.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain MCM PF00493.18 KOS19480.1 - 3.1e-134 446.9 0.1 8.8e-134 445.4 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KOS19480.1 - 8.4e-26 90.8 0.2 4.6e-25 88.4 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KOS19480.1 - 2e-07 30.4 0.1 1.2e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KOS19480.1 - 5.7e-07 29.3 0.0 2.6e-06 27.2 0.0 2.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 KOS19480.1 - 0.0015 18.9 2.4 0.0023 18.3 0.1 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KOS19480.1 - 0.011 15.3 0.0 0.038 13.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KOS19480.1 - 0.13 11.7 0.0 0.84 9.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.4 KOS19481.1 - 1.4e-84 283.6 0.0 1.8e-84 283.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 KOS19481.1 - 0.0089 16.0 0.3 0.023 14.6 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain RRS1 PF04939.7 KOS19482.1 - 4e-60 202.0 6.0 4.6e-60 201.8 4.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.22 KOS19483.1 - 2e-21 76.1 0.1 9.2e-21 74.0 0.1 2.0 1 1 0 1 1 1 1 RhoGAP domain ABC_tran PF00005.22 KOS19484.1 - 4.1e-35 121.0 0.0 4.7e-17 62.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KOS19484.1 - 2.2e-14 54.1 5.4 0.0015 18.5 0.0 4.4 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 KOS19484.1 - 5.3e-13 48.7 0.3 1.4e-05 24.4 0.0 3.3 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain RLI PF04068.10 KOS19484.1 - 1.2e-12 47.1 4.7 1.2e-12 47.1 3.3 2.1 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_15 PF13175.1 KOS19484.1 - 5.1e-07 29.0 0.2 0.82 8.6 0.0 4.3 4 1 1 5 5 5 1 AAA ATPase domain AAA_17 PF13207.1 KOS19484.1 - 7.7e-07 29.9 0.1 0.022 15.5 0.0 2.8 2 2 0 2 2 2 2 AAA domain Fer4 PF00037.22 KOS19484.1 - 8.6e-06 25.1 2.7 8.6e-06 25.1 1.9 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_18 PF13238.1 KOS19484.1 - 2.3e-05 24.7 0.2 0.32 11.2 0.0 2.9 3 1 0 3 3 2 2 AAA domain AAA PF00004.24 KOS19484.1 - 3e-05 24.2 0.0 0.02 15.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KOS19484.1 - 4.5e-05 22.9 0.2 0.067 12.7 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KOS19484.1 - 5.2e-05 23.4 0.0 0.0091 16.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KOS19484.1 - 0.00026 20.2 1.5 0.84 8.8 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 Fer4_21 PF14697.1 KOS19484.1 - 0.00027 20.7 10.4 0.00051 19.8 7.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_16 PF13191.1 KOS19484.1 - 0.00031 20.7 0.1 0.1 12.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 KOS19484.1 - 0.00038 20.1 0.8 0.07 12.8 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KOS19484.1 - 0.00041 20.4 0.0 0.26 11.4 0.0 2.8 2 0 0 2 2 2 1 RNA helicase UPF0079 PF02367.12 KOS19484.1 - 0.00054 19.5 0.3 0.0074 15.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KOS19484.1 - 0.00083 19.0 0.1 0.32 10.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.1 KOS19484.1 - 0.00094 19.5 0.0 0.06 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KOS19484.1 - 0.0017 17.7 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS19484.1 - 0.0017 18.2 0.2 0.18 11.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain VirE PF05272.6 KOS19484.1 - 0.0019 17.7 0.1 1.6 8.1 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E Fer4_7 PF12838.2 KOS19484.1 - 0.0028 17.9 7.2 0.0059 16.9 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain SRP54 PF00448.17 KOS19484.1 - 0.003 17.0 2.8 0.075 12.4 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.2 KOS19484.1 - 0.0061 16.3 1.6 0.0061 16.3 1.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Thymidylate_kin PF02223.12 KOS19484.1 - 0.0096 15.3 0.9 2.1 7.6 0.0 3.0 3 0 0 3 3 3 1 Thymidylate kinase Rad17 PF03215.10 KOS19484.1 - 0.011 14.4 0.0 0.11 11.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 KOS19484.1 - 0.014 15.1 1.2 0.29 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 KOS19484.1 - 0.02 13.4 0.0 0.02 13.4 0.0 2.3 4 0 0 4 4 3 0 AAA domain Fer4_10 PF13237.1 KOS19484.1 - 0.025 14.3 1.7 0.025 14.3 1.1 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Miro PF08477.8 KOS19484.1 - 0.025 15.0 0.1 2.1 8.8 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein AAA_28 PF13521.1 KOS19484.1 - 0.03 14.2 0.1 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KOS19484.1 - 0.05 13.1 0.2 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KOS19484.1 - 0.064 13.1 0.1 8.8 6.3 0.0 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.1 KOS19484.1 - 0.07 13.8 0.2 0.07 13.8 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain NB-ARC PF00931.17 KOS19484.1 - 0.081 11.7 0.0 3.7 6.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 KOS19484.1 - 0.096 12.1 3.4 0.39 10.1 0.1 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_8 PF13183.1 KOS19484.1 - 0.2 11.7 9.1 0.61 10.1 6.4 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain T2SE PF00437.15 KOS19484.1 - 0.2 10.5 0.8 3.1 6.6 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein NTPase_1 PF03266.10 KOS19484.1 - 0.22 11.2 1.9 9.1 5.9 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 KOS19484.1 - 0.23 11.3 1.7 21 5.0 0.1 3.3 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KOS19484.1 - 0.46 10.0 1.7 3.5 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_2 PF12797.2 KOS19484.1 - 0.48 10.4 11.9 0.19 11.7 1.3 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.1 KOS19484.1 - 0.77 10.0 13.4 0.051 13.8 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain SNF2_N PF00176.18 KOS19485.1 - 5.6e-62 209.2 0.0 1e-61 208.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KOS19485.1 - 3.1e-26 90.7 7.1 3.6e-15 55.3 1.4 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KOS19485.1 - 2.3e-14 53.0 0.0 8e-14 51.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Inositol_P PF00459.20 KOS19486.1 - 3.1e-41 141.4 0.9 1.7e-27 96.3 0.0 2.1 2 0 0 2 2 2 2 Inositol monophosphatase family AAA PF00004.24 KOS19487.1 - 1.3e-56 190.3 0.0 2.1e-43 147.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KOS19487.1 - 3.9e-26 90.9 0.7 7.6e-26 89.9 0.1 1.8 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KOS19487.1 - 4.8e-11 42.9 6.9 3.6e-06 27.0 0.1 4.3 3 2 1 4 4 4 2 AAA ATPase domain AAA_2 PF07724.9 KOS19487.1 - 1.5e-08 34.7 0.0 0.00036 20.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KOS19487.1 - 4e-08 34.1 0.0 0.003 18.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KOS19487.1 - 4.4e-08 32.9 0.6 4.4e-05 23.1 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 KOS19487.1 - 6.4e-08 32.8 1.1 0.00053 20.1 0.1 3.4 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KOS19487.1 - 1.5e-07 31.7 0.1 9.3e-05 22.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KOS19487.1 - 6.8e-06 26.0 0.0 0.024 14.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 KOS19487.1 - 8.9e-06 25.7 0.0 0.0013 18.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 KOS19487.1 - 9e-06 25.4 0.7 0.033 13.9 0.1 3.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KOS19487.1 - 1e-05 24.7 0.0 0.019 14.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RuvB_N PF05496.7 KOS19487.1 - 2.1e-05 23.6 0.0 0.014 14.4 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KOS19487.1 - 0.00015 21.2 0.2 0.29 10.5 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.1 KOS19487.1 - 0.00018 21.4 0.1 0.3 10.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KOS19487.1 - 0.00023 20.7 0.1 0.0048 16.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 KOS19487.1 - 0.00047 18.9 0.0 0.75 8.4 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus SKI PF01202.17 KOS19487.1 - 0.00053 19.8 0.1 0.28 11.0 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase AAA_19 PF13245.1 KOS19487.1 - 0.00058 19.5 0.0 1.8 8.3 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_28 PF13521.1 KOS19487.1 - 0.0012 18.8 0.1 0.51 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KOS19487.1 - 0.0013 18.8 0.0 2.5 8.2 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 KOS19487.1 - 0.002 17.3 0.1 0.68 9.0 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 KOS19487.1 - 0.0025 18.1 0.0 0.73 10.1 0.0 2.6 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.21 KOS19487.1 - 0.0029 17.0 0.0 0.17 11.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 KOS19487.1 - 0.0036 16.7 3.1 1.9 7.8 0.3 4.1 2 2 2 4 4 4 1 AAA domain DUF815 PF05673.8 KOS19487.1 - 0.0063 15.4 0.0 0.098 11.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) APS_kinase PF01583.15 KOS19487.1 - 0.0065 16.1 0.2 0.029 14.0 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase Cytidylate_kin2 PF13189.1 KOS19487.1 - 0.011 15.6 0.0 5.4 6.8 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase-like family NB-ARC PF00931.17 KOS19487.1 - 0.019 13.8 0.1 5.6 5.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 KOS19487.1 - 0.02 14.0 0.0 4.8 6.2 0.0 2.4 2 0 0 2 2 2 0 KaiC Arch_ATPase PF01637.13 KOS19487.1 - 0.022 14.4 0.6 1.7 8.2 0.0 3.0 2 2 1 3 3 3 0 Archaeal ATPase AAA_3 PF07726.6 KOS19487.1 - 0.028 14.0 0.0 6.9 6.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KOS19487.1 - 0.029 13.9 0.6 6.7 6.2 0.2 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KOS19487.1 - 0.046 13.1 0.2 0.73 9.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.11 KOS19487.1 - 0.058 12.6 0.1 7.1 5.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein KAP_NTPase PF07693.9 KOS19487.1 - 0.06 12.3 0.0 3.2 6.6 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain KTI12 PF08433.5 KOS19487.1 - 0.061 12.5 0.1 0.38 9.9 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.10 KOS19487.1 - 0.073 12.7 0.1 1.8 8.2 0.0 2.5 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.4 KOS19487.1 - 0.12 11.3 0.0 7.2 5.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 KOS19487.1 - 0.2 10.2 0.0 0.51 8.9 0.0 1.7 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF4110 PF13422.1 KOS19489.1 - 4.3e-29 100.2 1.1 4.3e-29 100.2 0.7 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 KOS19489.1 - 1.3e-27 95.2 15.9 1.1e-09 38.1 0.1 5.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KOS19489.1 - 6.3e-26 89.9 11.9 1.8e-08 33.9 0.0 6.6 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KOS19489.1 - 8.5e-15 54.3 3.6 1.5e-05 24.8 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KOS19489.1 - 8.6e-15 54.1 2.7 0.00058 19.9 0.1 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KOS19489.1 - 1.8e-12 46.5 0.2 1.3e-05 24.6 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 KOS19489.1 - 6.7e-12 44.6 6.9 0.00012 21.7 0.0 5.9 6 1 0 6 6 6 3 Kelch motif Tenui_PVC2 PF06656.6 KOS19489.1 - 0.57 7.9 0.0 0.79 7.4 0.0 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein SGT1 PF07093.6 KOS19489.1 - 0.69 8.2 18.5 1.6 6.9 10.9 2.0 2 0 0 2 2 2 0 SGT1 protein 14-3-3 PF00244.15 KOS19490.1 - 2.5e-115 383.5 6.0 3e-115 383.2 4.1 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 KOS19490.1 - 0.03 13.8 7.0 1.4 8.3 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF837) zf-CSL PF05207.8 KOS19491.1 - 4.8e-14 51.5 0.2 1.2e-13 50.3 0.1 1.7 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 KOS19491.1 - 9.9e-11 41.2 0.8 2.2e-09 36.9 0.5 2.2 1 1 0 1 1 1 1 DnaJ domain Nsp1_C PF05064.8 KOS19492.1 - 2.2e-37 127.2 4.8 2.2e-37 127.2 3.3 2.0 2 0 0 2 2 2 1 Nsp1-like C-terminal region DUF3166 PF11365.3 KOS19492.1 - 0.00064 20.1 1.0 0.0063 16.9 0.9 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3166) TMCO5 PF14992.1 KOS19492.1 - 0.0016 17.6 3.6 0.0021 17.2 2.5 1.2 1 0 0 1 1 1 1 TMCO5 family DUF948 PF06103.6 KOS19492.1 - 0.0044 16.8 1.3 0.041 13.7 0.1 2.5 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 KOS19492.1 - 0.0084 15.9 0.6 0.38 10.5 0.0 2.4 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus HAUS-augmin3 PF14932.1 KOS19492.1 - 0.0093 15.1 2.9 0.0093 15.1 2.0 2.3 3 0 0 3 3 3 1 HAUS augmin-like complex subunit 3 Reo_sigmaC PF04582.7 KOS19492.1 - 0.016 14.4 2.2 0.3 10.2 0.5 2.5 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF4200 PF13863.1 KOS19492.1 - 0.036 14.0 9.7 1.3 8.9 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) V-SNARE PF05008.10 KOS19492.1 - 0.039 14.1 10.8 0.27 11.4 1.2 3.3 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus MCPsignal PF00015.16 KOS19492.1 - 0.05 13.1 4.6 0.21 11.1 0.2 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain MerR-DNA-bind PF09278.6 KOS19492.1 - 0.072 13.4 4.3 6.6 7.2 0.1 2.7 2 0 0 2 2 2 0 MerR, DNA binding NPV_P10 PF05531.7 KOS19492.1 - 0.074 13.3 4.1 1.8 8.8 0.3 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 KOS19492.1 - 0.12 12.1 8.4 1.4 8.6 0.9 3.0 1 1 0 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.4 KOS19492.1 - 0.21 11.7 9.0 1.8 8.7 0.4 3.2 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 KOS19492.1 - 0.25 9.7 9.1 1.5 7.1 6.3 1.9 1 1 0 1 1 1 0 AAA domain Myosin_tail_1 PF01576.14 KOS19492.1 - 0.26 8.9 11.8 0.23 9.1 2.3 1.9 1 1 1 2 2 2 0 Myosin tail WXG100 PF06013.7 KOS19492.1 - 0.27 11.2 9.9 3 7.9 1.7 3.4 3 1 1 4 4 4 0 Proteins of 100 residues with WXG ERM PF00769.14 KOS19492.1 - 0.27 10.7 11.0 0.14 11.7 6.0 1.6 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF2203 PF09969.4 KOS19492.1 - 0.28 11.3 2.1 1.2 9.3 0.9 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) FlaC_arch PF05377.6 KOS19492.1 - 0.33 10.8 2.5 4.6 7.2 0.0 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Sec34 PF04136.10 KOS19492.1 - 0.42 10.3 3.4 2.1 8.0 0.4 2.3 1 1 1 2 2 2 0 Sec34-like family CENP-Q PF13094.1 KOS19492.1 - 0.48 10.4 11.7 4.3 7.3 8.1 2.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6 PF04111.7 KOS19492.1 - 0.48 9.4 11.9 2.7 6.9 3.0 1.9 1 1 0 2 2 2 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KOS19492.1 - 0.59 7.9 5.2 0.92 7.2 3.6 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 KOS19492.1 - 0.64 9.8 5.4 5.6 6.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Enkurin PF13864.1 KOS19492.1 - 0.67 10.2 5.9 1.3 9.2 0.7 2.5 2 1 0 2 2 2 0 Calmodulin-binding YlqD PF11068.3 KOS19492.1 - 0.99 9.4 7.8 0.4 10.7 2.4 2.2 1 1 1 2 2 2 0 YlqD protein GAS PF13851.1 KOS19492.1 - 1.2 8.2 9.2 1.7 7.7 0.3 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4298 PF14131.1 KOS19492.1 - 2 8.3 7.2 24 4.8 0.4 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4298) DUF972 PF06156.8 KOS19492.1 - 2.4 8.5 6.0 1.4 9.3 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Rotamase PF00639.16 KOS19492.1 - 2.5 8.9 7.1 2.2 9.0 0.4 2.8 1 1 2 3 3 3 0 PPIC-type PPIASE domain Prefoldin_2 PF01920.15 KOS19492.1 - 2.9 7.6 14.5 0.26 11.0 0.8 3.5 3 1 0 4 4 4 0 Prefoldin subunit DUF342 PF03961.8 KOS19492.1 - 3.5 5.9 6.7 1.1 7.5 2.1 1.7 1 1 2 3 3 3 0 Protein of unknown function (DUF342) Tropomyosin PF00261.15 KOS19492.1 - 3.7 6.5 12.9 6.7 5.7 2.6 2.4 1 1 1 2 2 2 0 Tropomyosin Syntaxin-6_N PF09177.6 KOS19492.1 - 7.2 7.0 9.5 24 5.4 2.1 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal IATP PF04568.7 KOS19493.1 - 1.4e-15 57.1 5.3 1.1e-13 51.0 1.4 2.1 2 0 0 2 2 2 2 Mitochondrial ATPase inhibitor, IATP FYVE_2 PF02318.11 KOS19493.1 - 0.58 10.0 2.2 0.85 9.5 1.6 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger tRNA-synt_1 PF00133.17 KOS19494.1 - 7e-219 727.7 0.1 5.7e-218 724.7 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KOS19494.1 - 2e-35 121.7 3.4 6.5e-35 120.1 2.4 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KOS19494.1 - 2.3e-15 56.1 0.0 4.4e-06 25.6 0.0 4.6 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KOS19494.1 - 7.6e-11 41.6 10.6 3.8e-10 39.3 0.0 3.2 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 KOS19494.1 - 0.00013 21.9 10.2 0.00013 21.9 7.1 3.0 2 1 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm DEAD PF00270.24 KOS19497.1 - 1.2e-40 138.8 0.0 6.4e-40 136.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS19497.1 - 1.3e-24 85.8 0.1 3.1e-24 84.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 KOS19497.1 - 0.00052 20.2 1.5 0.00052 20.2 1.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) ResIII PF04851.10 KOS19497.1 - 0.017 14.9 0.0 0.068 12.9 0.0 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit GTP_EFTU PF00009.22 KOS19498.1 - 4.6e-38 130.5 0.0 8e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KOS19498.1 - 4.7e-36 122.6 0.3 9.6e-36 121.7 0.2 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KOS19498.1 - 1.2e-09 38.1 0.2 2.4e-09 37.1 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KOS19498.1 - 0.0093 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KOS19498.1 - 0.083 12.7 0.0 0.43 10.3 0.0 2.2 2 1 1 3 3 3 0 Dynamin family AraC_binding_2 PF14525.1 KOS19499.1 - 0.28 10.7 3.2 0.11 12.1 0.3 1.6 2 0 0 2 2 2 0 AraC-binding-like domain CAF-1_p60_C PF15512.1 KOS19499.1 - 0.88 9.9 8.7 1.6 9.1 6.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal Shikimate_dh_N PF08501.6 KOS19500.1 - 1.2e-26 92.5 0.0 1.7e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain DHquinase_I PF01487.10 KOS19500.1 - 2.9e-08 33.6 0.0 5.7e-08 32.6 0.0 1.5 2 0 0 2 2 2 1 Type I 3-dehydroquinase Abhydrolase_3 PF07859.8 KOS19501.1 - 1.4e-20 73.8 0.1 1.9e-20 73.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KOS19501.1 - 1e-19 70.4 0.0 1.8e-12 46.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) COesterase PF00135.23 KOS19501.1 - 0.0026 16.5 0.9 0.34 9.5 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 KOS19501.1 - 0.045 13.5 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family CBFD_NFYB_HMF PF00808.18 KOS19502.1 - 4.6e-13 49.0 0.8 7.6e-13 48.3 0.6 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KOS19502.1 - 0.0004 20.4 0.1 0.00068 19.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF788 PF05620.6 KOS19503.1 - 4e-41 140.6 0.0 4.4e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) DUF3605 PF12239.3 KOS19504.1 - 8.2e-54 181.7 0.0 9.7e-54 181.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Ras PF00071.17 KOS19506.1 - 6.3e-57 191.4 0.0 7.4e-57 191.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS19506.1 - 3.5e-20 72.6 0.0 5.2e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS19506.1 - 1.1e-14 54.0 0.0 1.4e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KOS19506.1 - 2.8e-07 30.1 0.0 6.6e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KOS19506.1 - 5e-06 25.8 0.0 6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KOS19506.1 - 0.00012 21.9 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KOS19506.1 - 0.0038 17.2 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KOS19506.1 - 0.056 13.5 0.0 0.21 11.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain PI3_PI4_kinase PF00454.22 KOS19507.1 - 1.4e-25 90.1 0.0 2.5e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 KOS19507.1 - 1.7e-18 66.0 0.3 3.5e-18 65.0 0.2 1.5 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 Kri1_C PF12936.2 KOS19509.1 - 1.5e-27 95.3 1.1 1.5e-27 95.3 0.8 4.5 4 1 1 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 KOS19509.1 - 9e-23 80.4 24.6 9e-23 80.4 17.1 5.8 5 2 1 6 6 6 1 KRI1-like family LRR19-TM PF15176.1 KOS19509.1 - 8.6 6.1 13.5 0.74 9.5 0.6 3.3 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Peptidase_C50 PF03568.12 KOS19510.1 - 1.2e-111 373.0 0.0 1.8e-111 372.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 KOS19510.1 - 1.7e-07 31.0 1.9 0.88 9.5 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat CENP-B_dimeris PF09026.5 KOS19510.1 - 0.002 18.3 0.5 0.041 14.1 0.5 2.4 2 0 0 2 2 2 1 Centromere protein B dimerisation domain TPR_8 PF13181.1 KOS19510.1 - 0.053 13.3 0.0 27 4.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KOS19510.1 - 0.061 13.2 0.3 19 5.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.4 KOS19510.1 - 0.27 10.6 2.7 15 4.9 0.1 3.5 3 1 0 3 3 3 0 26S proteasome subunit RPN7 Glyco_hydro_7 PF00840.15 KOS19511.1 - 4.9e-206 684.1 23.7 6.5e-206 683.8 16.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 KOS19511.1 - 1.2e-13 50.4 11.0 1.2e-13 50.4 7.6 4.4 5 0 0 5 5 5 1 Fungal cellulose binding domain NmrA PF05368.8 KOS19512.1 - 5.8e-12 45.3 0.0 1.5e-10 40.7 0.0 2.3 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.20 KOS19512.1 - 0.019 14.9 0.0 0.044 13.6 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 KOS19512.1 - 0.096 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 KR domain GATase PF00117.23 KOS19513.1 - 7.7e-38 129.8 0.0 3e-37 127.9 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 KOS19513.1 - 3.3e-22 77.9 0.0 5.6e-22 77.2 0.0 1.5 1 1 0 1 1 1 1 GMP synthase C terminal domain Peptidase_C26 PF07722.8 KOS19513.1 - 2.3e-10 40.3 0.0 4.3e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 KOS19513.1 - 1.6e-07 30.5 0.0 1.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.16 KOS19513.1 - 0.00067 19.2 0.0 0.0054 16.2 0.0 2.1 2 0 0 2 2 2 1 Asparagine synthase tRNA_Me_trans PF03054.11 KOS19513.1 - 0.0032 16.0 0.1 0.0052 15.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 KOS19513.1 - 0.0065 15.9 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 KOS19513.1 - 0.017 14.9 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.14 KOS19513.1 - 0.045 12.7 0.1 0.068 12.1 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.15 KOS19513.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 PP-loop family QueC PF06508.8 KOS19513.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC FA_desaturase PF00487.19 KOS19514.1 - 0.0065 15.9 0.1 0.0075 15.7 0.1 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Fungal_trans_2 PF11951.3 KOS19515.1 - 7.6e-50 169.6 3.9 1e-49 169.2 2.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS19515.1 - 1.4e-06 28.1 5.9 2.3e-06 27.4 4.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF222 PF02720.12 KOS19515.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF222) NAD_binding_4 PF07993.7 KOS19516.1 - 3.2e-18 65.5 0.0 3.8e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein ketoacyl-synt PF00109.21 KOS19517.1 - 3.3e-47 161.1 0.0 1e-46 159.4 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KOS19517.1 - 4.7e-46 157.5 0.0 4.3e-45 154.4 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KOS19517.1 - 2.7e-30 104.6 0.2 6.5e-30 103.4 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KOS19517.1 - 9.1e-07 28.3 0.0 1.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 KOS19517.1 - 0.00012 21.2 0.0 0.0002 20.4 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 KOS19517.1 - 0.0072 16.0 0.1 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ferritin_2 PF13668.1 KOS19518.1 - 2.1e-05 24.4 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Fungal_trans PF04082.13 KOS19519.1 - 2e-21 76.0 0.0 5e-21 74.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain CoaE PF01121.15 KOS19520.1 - 2e-42 144.6 0.0 4.6e-42 143.4 0.0 1.6 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 KOS19520.1 - 0.00018 22.3 1.0 0.0013 19.5 0.6 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KOS19520.1 - 0.0035 17.2 0.0 0.026 14.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 KOS19520.1 - 0.12 12.6 3.6 0.34 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain Transferase PF02458.10 KOS19521.1 - 0.015 13.8 0.0 0.28 9.5 0.0 2.6 2 1 0 2 2 2 0 Transferase family DUF2372 PF10178.4 KOS19522.1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) Trp_DMAT PF11991.3 KOS19523.1 - 9.4e-52 176.4 0.0 1.2e-51 176.0 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase 3Beta_HSD PF01073.14 KOS19528.1 - 2.3e-39 134.7 0.0 3e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KOS19528.1 - 3.1e-24 85.7 0.0 4e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KOS19528.1 - 1.7e-12 46.8 0.0 2.8e-10 39.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KOS19528.1 - 1.4e-07 31.7 0.0 1.9e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KOS19528.1 - 2.8e-07 29.7 0.0 4.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KOS19528.1 - 7e-05 22.7 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KOS19528.1 - 0.00024 20.1 0.0 0.00043 19.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GST_C_2 PF13410.1 KOS19529.1 - 2.1e-14 53.1 0.0 5e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KOS19529.1 - 5.2e-14 51.9 0.0 8.7e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KOS19529.1 - 1.4e-06 28.2 0.0 2.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KOS19529.1 - 0.0062 16.9 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Dala_Dala_lig_C PF07478.8 KOS19530.1 - 3.6e-20 72.2 0.0 5.3e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 KOS19530.1 - 1.7e-07 31.1 0.0 6.3e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KOS19530.1 - 0.0032 17.3 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KOS19530.1 - 0.0045 15.7 0.0 0.21 10.2 0.0 2.6 2 1 1 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Cupin_8 PF13621.1 KOS19531.1 - 4.5e-34 118.0 0.0 5.6e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KOS19531.1 - 7.1e-05 22.1 0.0 0.0001 21.6 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein DAO PF01266.19 KOS19532.1 - 3.5e-49 167.6 0.4 6e-49 166.8 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KOS19532.1 - 3.1e-07 29.8 0.6 1.4e-06 27.6 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KOS19532.1 - 0.00029 19.7 3.0 0.00043 19.2 1.7 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KOS19532.1 - 0.00072 19.5 0.5 0.0021 18.0 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KOS19532.1 - 0.0013 18.6 0.1 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KOS19532.1 - 0.0061 15.5 0.0 0.52 9.1 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 KOS19532.1 - 0.022 13.6 0.1 0.067 12.0 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KOS19532.1 - 0.024 13.1 1.2 0.036 12.5 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 KOS19532.1 - 0.03 14.7 0.9 0.12 12.7 0.8 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KOS19532.1 - 0.044 12.8 0.3 0.095 11.7 0.2 1.5 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 KOS19532.1 - 0.056 13.0 1.2 0.086 12.4 0.3 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KOS19532.1 - 0.092 12.8 0.0 0.76 9.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KOS19532.1 - 0.2 10.6 1.3 0.61 9.0 0.5 2.0 2 0 0 2 2 2 0 FAD binding domain RGS PF00615.14 KOS19533.1 - 1.1e-07 31.9 0.0 1.7e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_C48 PF02902.14 KOS19534.1 - 5.8e-13 48.9 0.0 1.3e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Med15 PF09606.5 KOS19534.1 - 0.0054 15.0 18.2 0.0089 14.2 12.6 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Phe_hydrox_dim PF07976.7 KOS19535.1 - 1.3e-39 135.5 0.0 1.9e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_3 PF01494.14 KOS19535.1 - 6e-33 114.3 0.0 8.6e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 KOS19538.1 - 1.2e-34 119.5 63.7 1.5e-23 83.1 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KOS19538.1 - 0.0083 15.8 8.5 0.06 13.1 0.1 3.5 3 0 0 3 3 3 1 MFS_1 like family TRI12 PF06609.8 KOS19538.1 - 0.84 7.7 11.9 0.44 8.6 2.2 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) ATP-synt_G PF04718.10 KOS19539.1 - 4.3e-29 101.1 0.5 7.5e-29 100.4 0.1 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit TFIIA PF03153.8 KOS19540.1 - 6e-64 217.2 0.5 1.3e-51 176.6 0.0 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF3295 PF11702.3 KOS19540.1 - 0.16 10.9 0.7 0.22 10.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) WD40 PF00400.27 KOS19541.1 - 7.1e-22 76.4 20.8 3.6e-06 26.6 0.1 7.2 6 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KOS19541.1 - 6.3e-06 26.0 0.6 0.00075 19.2 0.1 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Kelch_4 PF13418.1 KOS19542.1 - 7.2e-28 96.1 5.4 1.2e-08 34.5 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KOS19542.1 - 5.9e-25 86.7 1.1 1.3e-07 31.4 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 KOS19542.1 - 1.1e-22 79.2 1.7 0.00019 21.4 0.0 5.3 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.1 KOS19542.1 - 1.2e-19 69.9 6.3 3.7e-07 30.1 0.0 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.20 KOS19542.1 - 3.4e-19 68.0 0.5 5.7e-06 25.7 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 KOS19542.1 - 3.7e-17 61.3 2.5 0.00025 20.7 0.0 4.6 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 KOS19542.1 - 1.8e-08 34.3 0.0 3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Rax2 PF12768.2 KOS19542.1 - 0.075 12.2 0.5 0.94 8.6 0.0 2.7 2 1 1 3 3 3 0 Cortical protein marker for cell polarity HIG_1_N PF04588.8 KOS19545.1 - 6.4e-06 25.8 5.6 2.1e-05 24.1 3.9 1.9 1 1 0 1 1 1 1 Hypoxia induced protein conserved region Kelch_3 PF13415.1 KOS19546.1 - 2.2e-45 151.8 14.5 2.3e-08 33.9 0.0 7.0 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 KOS19546.1 - 1.3e-43 146.5 15.6 1.5e-09 37.5 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KOS19546.1 - 1.8e-38 129.9 16.8 2.3e-07 30.6 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 KOS19546.1 - 3e-36 122.7 18.5 1.7e-08 33.8 0.2 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KOS19546.1 - 3.9e-32 109.0 13.7 4.3e-06 26.6 0.1 6.4 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KOS19546.1 - 3.2e-30 102.7 16.5 1.4e-09 37.3 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Dus PF01207.12 KOS19547.1 - 1.9e-41 141.8 0.0 3.2e-30 105.0 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 KOS19547.1 - 0.037 13.7 5.9 0.43 10.3 0.3 2.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Peroxin-13_N PF04088.8 KOS19548.1 - 1.5e-54 184.1 0.2 2.5e-54 183.5 0.2 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 KOS19548.1 - 1e-12 47.3 0.0 1.6e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KOS19548.1 - 1.6e-09 37.2 0.1 3.3e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KOS19548.1 - 8.1e-09 34.7 0.0 1.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.6 KOS19548.1 - 0.035 14.3 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain ADK PF00406.17 KOS19549.1 - 6.7e-44 149.4 0.0 8.9e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 KOS19549.1 - 1.5e-09 37.8 0.0 4.1e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KOS19549.1 - 7.9e-07 29.4 0.0 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS19549.1 - 3.1e-06 28.0 0.0 5.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KOS19549.1 - 0.012 14.9 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.7 KOS19549.1 - 0.095 11.7 0.0 0.24 10.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 KOS19549.1 - 0.11 12.2 0.8 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AIF-MLS PF14962.1 KOS19549.1 - 0.11 12.1 0.2 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF3818 PF12825.2 KOS19550.1 - 1.8e-132 441.1 4.0 2.8e-132 440.5 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KOS19550.1 - 2.3e-41 140.6 0.9 4.9e-41 139.5 0.6 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.19 KOS19550.1 - 0.0036 17.0 1.6 0.0059 16.3 0.2 2.1 2 0 0 2 2 2 1 PX domain Pkinase PF00069.20 KOS19551.1 - 1e-75 254.2 0.0 1.4e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19551.1 - 1.5e-36 125.8 0.0 1.9e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KOS19551.1 - 1.5e-14 53.8 0.1 2.9e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KOS19551.1 - 3.2e-07 29.6 0.0 8.5e-07 28.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KOS19551.1 - 0.0087 15.1 0.1 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KOS19551.1 - 0.025 13.3 0.1 0.046 12.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 KOS19551.1 - 0.044 13.1 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PCI PF01399.22 KOS19552.1 - 2.4e-14 53.5 0.0 1.4e-13 51.0 0.0 2.3 2 0 0 2 2 2 1 PCI domain DUF2383 PF09537.5 KOS19552.1 - 0.16 12.1 2.0 5.7 7.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) DUF883 PF05957.8 KOS19553.1 - 0.007 16.7 0.1 0.028 14.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) DUF1509 PF07420.6 KOS19553.1 - 1 8.5 12.5 1.4 8.0 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DUF4187 PF13821.1 KOS19554.1 - 6.6e-17 60.8 0.7 2.1e-16 59.2 0.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 KOS19554.1 - 3.4e-05 23.5 12.0 0.00026 20.7 8.3 2.2 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KOS19554.1 - 0.091 12.6 6.4 0.52 10.2 4.5 2.4 1 0 0 1 1 1 0 DExH-box splicing factor binding site DUF4484 PF14831.1 KOS19554.1 - 2.3 8.2 6.3 0.29 11.2 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) SlyX PF04102.7 KOS19555.1 - 0.0047 17.2 6.8 0.042 14.2 1.1 2.6 2 0 0 2 2 2 1 SlyX Reo_sigmaC PF04582.7 KOS19555.1 - 0.013 14.6 0.4 0.019 14.1 0.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Peptidase_S64 PF08192.6 KOS19555.1 - 0.017 13.5 0.1 0.022 13.0 0.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 Spc7 PF08317.6 KOS19555.1 - 0.044 12.4 2.9 0.063 11.9 2.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Med9 PF07544.8 KOS19555.1 - 0.054 13.2 3.2 0.79 9.4 0.8 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF607 PF04678.8 KOS19555.1 - 0.073 12.9 3.7 0.29 11.0 2.6 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF607 DUF2383 PF09537.5 KOS19555.1 - 0.11 12.7 2.3 0.14 12.3 0.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2383) Fib_alpha PF08702.5 KOS19555.1 - 0.12 12.5 1.8 0.19 11.8 1.2 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 KOS19555.1 - 0.2 11.1 2.8 0.22 11.0 0.3 2.1 2 0 0 2 2 2 0 Septum formation initiator WASH_WAHD PF11945.3 KOS19555.1 - 0.25 10.5 4.5 0.32 10.2 1.6 2.2 2 1 1 3 3 3 0 WAHD domain of WASH complex Prefoldin_2 PF01920.15 KOS19555.1 - 0.3 10.8 3.6 4.3 7.1 2.6 2.3 1 1 1 2 2 2 0 Prefoldin subunit CENP-F_leu_zip PF10473.4 KOS19555.1 - 0.46 10.3 5.4 1.7 8.5 3.7 1.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 KOS19555.1 - 0.65 9.8 5.5 0.42 10.5 1.5 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 KOS19555.1 - 0.87 9.3 3.6 3.9 7.2 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GAT PF03127.9 KOS19555.1 - 1 9.3 4.3 6.9 6.7 0.4 2.3 1 1 1 2 2 2 0 GAT domain Mnd1 PF03962.10 KOS19555.1 - 1.5 8.4 6.0 12 5.4 4.2 2.2 1 1 0 1 1 1 0 Mnd1 family T2SF PF00482.18 KOS19555.1 - 2.1 8.2 3.9 86 3.0 2.7 2.5 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F EMP24_GP25L PF01105.19 KOS19555.1 - 2.5 7.7 7.8 35 4.0 5.4 2.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Neisseria_TspB PF05616.8 KOS19555.1 - 4.2 5.6 6.9 6.2 5.0 4.8 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein ABC_tran_2 PF12848.2 KOS19555.1 - 7.1 6.5 6.7 4 7.3 3.0 1.8 2 0 0 2 2 2 0 ABC transporter Cgr1 PF03879.9 KOS19556.1 - 8.5e-37 125.6 32.6 1e-36 125.3 22.6 1.0 1 0 0 1 1 1 1 Cgr1 family RR_TM4-6 PF06459.7 KOS19556.1 - 0.091 12.6 16.4 0.1 12.4 11.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PRP1_N PF06424.7 KOS19556.1 - 0.21 11.8 12.9 0.26 11.6 8.9 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Frigida PF07899.6 KOS19556.1 - 0.88 8.2 13.7 1 8.0 9.5 1.0 1 0 0 1 1 1 0 Frigida-like protein Prismane PF03063.15 KOS19556.1 - 1.6 7.0 5.3 1.8 6.8 3.7 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family GAGA_bind PF06217.7 KOS19556.1 - 1.7 8.5 14.6 1.8 8.4 10.1 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2422 PF10337.4 KOS19556.1 - 2 7.0 7.0 2.5 6.7 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DDRGK PF09756.4 KOS19556.1 - 3 7.2 25.2 3.6 6.9 17.5 1.2 1 0 0 1 1 1 0 DDRGK domain Ndufs5 PF10200.4 KOS19556.1 - 7.5 6.6 12.1 19 5.3 8.0 1.9 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa GRA6 PF05084.8 KOS19556.1 - 7.6 5.9 7.9 9.6 5.6 5.4 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Membr_traf_MHD PF10540.4 KOS19557.1 - 3e-21 75.6 0.0 3e-21 75.6 0.0 2.1 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KOS19557.1 - 4e-18 65.0 0.1 9.6e-18 63.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 KOS19557.1 - 1.1e-07 30.5 0.7 1.9e-07 29.7 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF810) ArfGap PF01412.13 KOS19558.1 - 4e-32 110.4 0.0 4e-32 110.4 0.0 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 KOS19558.1 - 4.9e-12 45.9 0.1 1.2e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 PH domain SIN1 PF05422.7 KOS19560.1 - 7.7e-38 130.2 0.0 5.4e-19 68.1 0.0 3.3 3 1 0 3 3 3 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 KOS19560.1 - 0.022 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 GLUT4 regulating protein TUG FAM176 PF14851.1 KOS19560.1 - 2.2 7.9 11.8 4.7 6.8 0.3 3.4 3 0 0 3 3 3 0 FAM176 family PRCC PF10253.4 KOS19561.1 - 2.2e-33 116.4 4.7 2.2e-33 116.4 3.3 3.4 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting E1_dh PF00676.15 KOS19563.1 - 1.4e-111 372.0 0.3 1.8e-111 371.6 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KOS19563.1 - 0.00069 18.6 0.7 0.0013 17.7 0.0 1.9 3 0 0 3 3 3 1 1-deoxy-D-xylulose-5-phosphate synthase WD40 PF00400.27 KOS19564.1 - 3.3e-52 172.6 15.4 3.2e-10 39.4 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KOS19564.1 - 1.3e-12 47.2 0.6 2.3e-12 46.4 0.4 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KOS19564.1 - 1.3e-11 43.3 10.3 0.01 14.0 0.1 6.0 1 1 5 6 6 6 5 Nucleoporin Nup120/160 F-box PF00646.28 KOS19564.1 - 2.3e-06 27.0 2.0 5.5e-06 25.9 1.4 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 KOS19564.1 - 0.00046 19.7 4.6 0.06 12.7 0.6 3.6 2 1 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 KOS19564.1 - 0.0024 18.0 3.0 3.4 8.0 0.1 4.7 4 1 0 4 4 4 1 PQQ-like domain Nucleoporin_N PF08801.6 KOS19564.1 - 0.023 13.4 0.0 0.43 9.2 0.0 2.2 1 1 0 2 2 2 0 Nup133 N terminal like Zip PF02535.17 KOS19565.1 - 4.6e-31 108.0 16.0 1.2e-25 90.1 4.4 2.9 2 1 0 2 2 2 2 ZIP Zinc transporter BRF1 PF07741.8 KOS19566.1 - 0.0041 17.3 4.8 0.0069 16.5 3.3 1.4 1 0 0 1 1 1 1 Brf1-like TBP-binding domain Caldesmon PF02029.10 KOS19566.1 - 0.38 9.1 17.0 0.091 11.1 9.7 1.4 2 0 0 2 2 2 0 Caldesmon Dyp_perox PF04261.7 KOS19567.1 - 2.5e-82 276.1 0.0 2.9e-82 275.9 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family Lipoxygenase PF00305.14 KOS19568.1 - 1.2e-50 172.2 0.1 1.7e-50 171.7 0.1 1.2 1 0 0 1 1 1 1 Lipoxygenase NADH-u_ox-rdase PF10785.4 KOS19569.1 - 2.1e-33 114.3 0.3 3.9e-33 113.5 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 KOS19569.1 - 1.8e-31 107.7 0.0 2.6e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit GMC_oxred_N PF00732.14 KOS19570.1 - 3.2e-09 36.3 0.0 6.1e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KOS19571.1 - 1.8e-05 25.0 0.1 0.00033 20.9 0.0 2.5 2 0 0 2 2 2 1 GMC oxidoreductase Sdh_cyt PF01127.17 KOS19571.1 - 0.012 15.4 1.3 0.023 14.5 0.9 1.4 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Snf7 PF03357.16 KOS19573.1 - 3e-08 33.2 22.3 3.4e-08 33.0 15.1 1.4 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.9 KOS19573.1 - 0.0047 16.3 6.0 0.012 14.9 4.1 1.8 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway ASL_C PF08328.6 KOS19573.1 - 0.044 13.6 5.1 0.049 13.4 2.4 1.9 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminal DUF427 PF04248.7 KOS19574.1 - 1.6e-29 101.3 0.1 2.1e-29 101.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Xan_ur_permease PF00860.15 KOS19575.1 - 1.3e-29 102.8 34.7 8.4e-19 67.3 8.2 3.6 3 1 1 4 4 4 3 Permease family 2OG-FeII_Oxy PF03171.15 KOS19576.1 - 0.0073 16.5 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KOS19576.1 - 0.027 14.9 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal PGP_phosphatase PF09419.5 KOS19578.1 - 5.3e-63 211.3 0.0 6e-63 211.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 KOS19578.1 - 0.00053 19.6 0.0 0.00097 18.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like SfsA PF03749.8 KOS19578.1 - 0.16 11.3 0.0 0.28 10.6 0.0 1.3 1 1 0 1 1 1 0 Sugar fermentation stimulation protein Glyco_hydro_16 PF00722.16 KOS19579.1 - 2.6e-07 30.1 0.0 3.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Tim17 PF02466.14 KOS19580.1 - 5.7e-50 168.6 8.7 7.3e-50 168.2 6.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 KOS19580.1 - 0.15 12.0 1.9 0.24 11.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF543) LEAP-2 PF07359.6 KOS19581.1 - 0.052 13.2 0.3 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Mucin PF01456.12 KOS19582.1 - 5.8 6.6 13.8 6 6.6 9.6 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein ORC2 PF04084.9 KOS19583.1 - 7.4e-97 324.0 0.0 9e-97 323.8 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 CTP_transf_1 PF01148.15 KOS19584.1 - 3.7e-06 26.7 8.1 3.7e-06 26.7 5.6 3.3 4 1 0 4 4 4 1 Cytidylyltransferase family DUF1445 PF07286.7 KOS19584.1 - 0.22 11.1 0.0 0.41 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1445) DUF2839 PF10999.3 KOS19584.1 - 1.3 9.1 4.1 8.8 6.4 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2839) DUF1754 PF08555.5 KOS19585.1 - 1.4e-13 51.2 19.0 2.5e-13 50.4 13.2 1.4 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Prothymosin PF03247.9 KOS19585.1 - 0.009 16.1 15.7 0.009 16.1 10.9 1.4 2 0 0 2 2 1 1 Prothymosin/parathymosin family Nucleo_P87 PF07267.6 KOS19585.1 - 0.051 12.2 10.4 0.054 12.1 7.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nucleoplasmin PF03066.10 KOS19585.1 - 0.06 12.8 6.5 0.081 12.4 4.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 KOS19585.1 - 0.08 10.7 4.7 0.084 10.7 3.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC27 PF09507.5 KOS19585.1 - 0.088 12.0 14.4 0.096 11.8 10.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sigma70_ner PF04546.8 KOS19585.1 - 0.28 10.7 10.8 0.36 10.4 7.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region FLO_LFY PF01698.11 KOS19585.1 - 0.36 9.6 8.9 0.45 9.3 6.2 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Myc_N PF01056.13 KOS19585.1 - 0.92 8.6 6.4 1 8.4 4.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region UBN_AB PF14075.1 KOS19585.1 - 1.7 8.2 8.9 2.2 7.9 6.2 1.0 1 0 0 1 1 1 0 Ubinuclein conserved middle domain NPR3 PF03666.8 KOS19585.1 - 1.8 7.0 5.0 1.9 6.9 3.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RRN3 PF05327.6 KOS19585.1 - 1.8 6.5 6.8 2.3 6.2 4.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RR_TM4-6 PF06459.7 KOS19585.1 - 3.1 7.6 10.8 3.6 7.3 7.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2201_N PF13203.1 KOS19585.1 - 3.3 6.7 10.7 4 6.5 7.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 KOS19585.1 - 4.7 5.1 13.9 5.3 4.9 9.6 1.0 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.11 KOS19585.1 - 7.6 5.9 15.3 10 5.5 10.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PBP1_TM PF14812.1 KOS19585.1 - 8.8 6.7 20.2 0.27 11.5 9.2 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDHD PF02862.12 KOS19585.1 - 9.4 5.9 7.0 11 5.7 4.9 1.2 1 0 0 1 1 1 0 DDHD domain AA_permease_2 PF13520.1 KOS19586.1 - 2.7e-63 213.9 38.1 3.5e-63 213.6 26.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KOS19586.1 - 3.6e-31 108.0 29.3 3.6e-31 108.0 20.3 1.8 2 0 0 2 2 2 1 Amino acid permease DUF382 PF04037.8 KOS19587.1 - 3.5e-37 127.1 13.4 2.8e-31 108.0 0.9 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF382) PSP PF04046.11 KOS19587.1 - 2.9e-18 64.9 7.3 5.9e-18 63.9 5.0 1.6 1 0 0 1 1 1 1 PSP Acetyltransf_1 PF00583.19 KOS19588.1 - 6.6e-12 45.2 0.0 1.4e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS19588.1 - 1.5e-07 31.4 0.1 2.6e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS19588.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KOS19588.1 - 0.00019 21.1 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KOS19588.1 - 0.0024 18.0 0.0 0.004 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KOS19588.1 - 0.0045 16.9 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KOS19588.1 - 0.029 14.2 0.1 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyoxalase_2 PF12681.2 KOS19588.1 - 0.052 14.1 0.0 0.15 12.6 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase-like domain DUF2156 PF09924.4 KOS19588.1 - 0.098 11.4 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) Complex1_LYR PF05347.10 KOS19589.1 - 4.6e-16 58.3 0.3 7e-16 57.7 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KOS19589.1 - 5.4e-16 58.5 0.3 7.8e-16 58.0 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KOS19589.1 - 0.0054 17.2 0.0 0.0079 16.6 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Vps8 PF12816.2 KOS19590.1 - 1.4e-73 246.3 0.0 2.1e-73 245.8 0.0 1.3 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 KOS19590.1 - 4.8e-05 22.9 0.0 0.19 11.3 0.0 4.0 4 0 0 4 4 4 2 Region in Clathrin and VPS IMPDH PF00478.20 KOS19591.1 - 7.1e-132 439.5 1.3 8.7e-132 439.2 0.9 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KOS19591.1 - 1.1e-14 53.9 0.1 1.1e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KOS19591.1 - 8.1e-09 35.0 3.7 0.00059 19.0 2.7 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 KOS19591.1 - 9e-08 31.3 0.5 2.1e-06 26.8 0.3 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KOS19591.1 - 0.00019 20.7 1.8 0.03 13.5 0.2 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 KOS19591.1 - 0.049 12.6 2.4 0.079 12.0 0.3 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG DEAD PF00270.24 KOS19592.1 - 2.3e-26 92.2 0.0 3.7e-15 55.8 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS19592.1 - 1.3e-22 79.4 0.0 4.2e-22 77.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Nop14 PF04147.7 KOS19592.1 - 3.1e-05 22.1 15.8 5.4e-05 21.3 10.9 1.3 1 0 0 1 1 1 1 Nop14-like family ResIII PF04851.10 KOS19592.1 - 4.3e-05 23.4 0.0 0.0001 22.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TFIIA PF03153.8 KOS19592.1 - 0.00013 22.0 11.6 0.00024 21.1 8.0 1.4 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 KOS19592.1 - 0.0015 16.7 11.6 0.0026 15.9 8.0 1.3 1 0 0 1 1 1 1 CDC45-like protein SAPS PF04499.10 KOS19592.1 - 0.019 13.6 1.9 0.033 12.8 1.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein T4SS-DNA_transf PF02534.9 KOS19592.1 - 0.043 12.3 0.0 0.085 11.4 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer NOA36 PF06524.7 KOS19592.1 - 3.2 6.9 20.1 5.9 6.0 13.9 1.3 1 0 0 1 1 1 0 NOA36 protein DUF1510 PF07423.6 KOS19592.1 - 3.6 6.8 26.2 0.2 10.9 12.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) PIG-P PF08510.7 KOS19593.1 - 1.1e-40 138.2 0.0 1.7e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 PIG-P DUF4118 PF13493.1 KOS19593.1 - 0.36 11.0 9.2 0.59 10.3 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) DPM2 PF07297.7 KOS19593.1 - 1.3 9.3 9.5 2.4 8.5 6.6 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Actin PF00022.14 KOS19594.1 - 8e-140 465.7 0.0 9.1e-140 465.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KOS19594.1 - 3.3e-06 25.9 0.2 0.022 13.3 0.0 2.6 2 1 1 3 3 3 2 MreB/Mbl protein DUF2401 PF10287.4 KOS19595.1 - 2.2e-74 249.9 0.0 2.5e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) Raffinose_syn PF05691.7 KOS19596.1 - 5.4e-08 30.8 0.0 6.7e-08 30.5 0.0 1.1 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 tRNA-synt_2 PF00152.15 KOS19597.1 - 1.3e-66 224.7 0.0 8.2e-52 176.0 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KOS19597.1 - 6.8e-07 28.7 0.0 0.00045 19.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 KOS19597.1 - 0.00031 20.5 0.3 0.00055 19.7 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 KOS19597.1 - 0.0009 18.8 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Nucleoplasmin PF03066.10 KOS19597.1 - 0.0022 17.5 2.9 0.0038 16.7 2.0 1.3 1 0 0 1 1 1 1 Nucleoplasmin CENP-B_dimeris PF09026.5 KOS19597.1 - 2.4 8.4 10.3 5.3 7.3 7.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain WD40 PF00400.27 KOS19598.1 - 8.2e-44 145.9 21.8 1e-10 41.0 0.4 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KOS19598.1 - 1.5e-05 24.3 0.6 0.055 12.9 0.0 3.9 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ctr PF04145.10 KOS19599.1 - 3.6e-21 75.7 1.5 6.9e-20 71.5 1.0 2.0 1 1 0 1 1 1 1 Ctr copper transporter family NUDIX PF00293.23 KOS19600.1 - 1.1e-12 47.8 0.5 2.2e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain DUF4129 PF13559.1 KOS19601.1 - 0.039 13.9 8.8 8.8 6.3 0.0 5.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4129) zf-Tim10_DDP PF02953.10 KOS19601.1 - 0.17 11.2 23.4 10 5.4 0.1 6.3 6 0 0 6 6 6 0 Tim10/DDP family zinc finger EXS PF03124.9 KOS19603.1 - 9.4e-99 330.7 6.7 1.1e-98 330.5 4.6 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.9 KOS19604.1 - 3.9e-43 147.4 4.5 5.2e-43 147.1 3.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 KOS19604.1 - 2.1e-12 46.8 7.5 3.1e-12 46.2 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS19604.1 - 2.1e-12 46.6 8.0 3.3e-12 46.0 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KOS19604.1 - 1.2e-09 37.6 6.5 1.9e-09 37.0 4.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS19604.1 - 1.7e-09 37.1 6.5 2.6e-09 36.5 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS19604.1 - 9.7e-09 34.8 5.5 1.6e-08 34.1 3.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KOS19604.1 - 1.6e-06 27.9 7.4 2.5e-06 27.2 5.1 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KOS19604.1 - 3.3e-06 27.1 3.6 6.1e-06 26.2 2.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KOS19604.1 - 2e-05 24.2 2.7 4.3e-05 23.2 1.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KOS19604.1 - 5.5e-05 22.7 4.2 0.0001 21.9 2.9 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 KOS19604.1 - 0.0028 17.1 1.4 0.0049 16.3 1.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 KOS19604.1 - 0.013 15.2 2.9 0.022 14.5 2.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 KOS19604.1 - 0.029 14.2 2.0 0.051 13.5 1.4 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.1 KOS19604.1 - 0.038 13.5 9.0 0.07 12.7 6.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 KOS19604.1 - 2 8.3 7.9 5.6 6.9 5.5 1.7 1 1 0 1 1 1 0 IBR domain zf-LYAR PF08790.6 KOS19605.1 - 5.1e-14 51.6 2.7 1.1e-13 50.5 1.9 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Abhydrolase_5 PF12695.2 KOS19606.1 - 2.5e-23 82.4 0.0 3.7e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS19606.1 - 1.8e-18 67.3 0.0 7.6e-17 61.9 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS19606.1 - 1.6e-06 27.8 0.0 0.0053 16.3 0.0 2.6 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KOS19606.1 - 1.7e-06 27.6 0.0 0.00055 19.4 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.7 KOS19606.1 - 1.5e-05 23.6 0.0 0.15 10.5 0.0 3.1 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DUF818 PF05677.7 KOS19606.1 - 2.6e-05 23.1 0.0 3.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.8 KOS19606.1 - 4.5e-05 22.9 0.0 0.00012 21.6 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.13 KOS19606.1 - 0.0019 17.5 0.0 1.3 8.2 0.0 2.9 3 0 0 3 3 3 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KOS19606.1 - 0.002 17.3 0.0 0.014 14.6 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KOS19606.1 - 0.02 14.7 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 KOS19606.1 - 0.032 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 KOS19606.1 - 0.099 12.2 0.1 0.54 9.8 0.1 2.3 1 1 0 1 1 1 0 PGAP1-like protein R3H PF01424.17 KOS19607.1 - 8.3e-11 41.4 0.0 1.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 KOS19607.1 - 0.001 18.9 12.3 0.001 18.9 8.5 15.2 16 2 0 16 16 16 6 NF-X1 type zinc finger WSC PF01822.14 KOS19608.1 - 7e-87 285.4 84.7 2.6e-18 65.7 6.2 5.3 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.6 KOS19608.1 - 5.8e-28 97.5 0.0 4.4e-27 94.7 0.0 2.3 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KOS19608.1 - 2.8e-19 69.0 0.0 5.2e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) AAA_2 PF07724.9 KOS19609.1 - 3.7e-48 163.6 0.2 3.9e-45 153.8 0.0 3.8 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KOS19609.1 - 1.7e-27 96.1 0.0 2.8e-14 53.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KOS19609.1 - 6.2e-24 83.7 1.8 1.5e-23 82.4 0.3 2.6 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KOS19609.1 - 6.3e-17 62.1 9.0 1.7e-06 28.1 0.0 5.9 3 2 3 6 6 6 2 AAA ATPase domain AAA_5 PF07728.9 KOS19609.1 - 3.1e-16 59.3 0.0 3.3e-10 39.8 0.0 3.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KOS19609.1 - 4.2e-13 49.5 0.5 5.9e-05 23.2 0.0 4.3 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 KOS19609.1 - 7.5e-10 38.5 0.0 2.3e-06 27.1 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 KOS19609.1 - 2.1e-08 35.0 4.5 0.0079 17.0 0.0 4.2 2 2 0 3 3 2 2 AAA domain AAA_14 PF13173.1 KOS19609.1 - 7.8e-08 32.2 0.1 0.018 14.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 KOS19609.1 - 9.6e-08 31.6 0.9 0.029 14.1 0.0 3.6 3 0 0 3 3 3 2 Part of AAA domain Clp_N PF02861.15 KOS19609.1 - 4.2e-07 29.7 7.7 0.0026 17.6 0.1 4.6 4 0 0 4 4 4 2 Clp amino terminal domain IstB_IS21 PF01695.12 KOS19609.1 - 7.9e-07 28.6 0.0 0.019 14.3 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 KOS19609.1 - 3e-06 27.5 5.7 0.012 15.8 0.0 4.2 4 0 0 4 4 4 2 AAA domain Arch_ATPase PF01637.13 KOS19609.1 - 1.3e-05 25.0 9.8 0.0084 15.8 0.2 5.3 3 2 1 4 4 4 1 Archaeal ATPase AAA_28 PF13521.1 KOS19609.1 - 1.7e-05 24.8 0.0 0.22 11.4 0.0 3.2 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KOS19609.1 - 1.7e-05 24.0 0.1 0.12 11.5 0.0 3.6 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KOS19609.1 - 3e-05 24.1 0.0 0.31 11.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase T2SE PF00437.15 KOS19609.1 - 3.6e-05 22.8 0.0 0.0031 16.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 KOS19609.1 - 4.2e-05 23.4 0.0 0.19 11.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KOS19609.1 - 5e-05 23.0 0.0 0.46 10.2 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KOS19609.1 - 5.9e-05 22.5 0.8 0.77 9.1 0.0 4.3 4 1 1 5 5 5 2 AAA domain Zeta_toxin PF06414.7 KOS19609.1 - 9.9e-05 21.5 0.0 0.017 14.2 0.0 3.1 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.6 KOS19609.1 - 0.00017 21.2 0.1 1 8.9 0.0 3.8 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KOS19609.1 - 0.00019 21.7 0.4 0.54 10.5 0.0 3.5 3 0 0 3 3 3 1 ABC transporter Sigma54_activ_2 PF14532.1 KOS19609.1 - 0.0004 20.4 0.0 1.9 8.5 0.0 3.4 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_10 PF12846.2 KOS19609.1 - 0.00042 19.8 3.7 0.12 11.7 0.0 4.6 5 1 0 5 5 5 1 AAA-like domain DUF258 PF03193.11 KOS19609.1 - 0.00075 18.7 0.0 0.42 9.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ResIII PF04851.10 KOS19609.1 - 0.00087 19.1 0.7 0.12 12.2 0.0 3.4 3 1 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_29 PF13555.1 KOS19609.1 - 0.0011 18.5 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Torsin PF06309.6 KOS19609.1 - 0.0011 18.8 0.0 0.0045 16.8 0.0 1.9 2 0 0 2 2 1 1 Torsin NACHT PF05729.7 KOS19609.1 - 0.0012 18.5 0.0 0.2 11.2 0.0 3.1 3 0 0 3 3 2 1 NACHT domain AAA_24 PF13479.1 KOS19609.1 - 0.0017 17.9 0.0 2.7 7.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 KOS19609.1 - 0.0021 17.7 0.1 0.44 10.2 0.0 3.7 4 0 0 4 4 3 1 NTPase AAA_21 PF13304.1 KOS19609.1 - 0.011 15.7 0.0 2.4 8.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.17 KOS19609.1 - 0.011 15.1 0.0 4.5 6.6 0.0 2.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 KOS19609.1 - 0.022 14.3 0.0 8.9 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 KOS19609.1 - 0.043 13.7 0.4 0.96 9.4 0.0 3.3 3 1 0 3 3 3 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KOS19609.1 - 0.051 13.1 0.0 10 5.5 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 KOS19609.1 - 0.059 12.8 0.0 6.1 6.3 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Glyco_hydro_47 PF01532.15 KOS19609.1 - 0.16 10.6 0.0 0.29 9.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 V_ATPase_I PF01496.14 KOS19609.1 - 2.1 6.0 4.1 4 5.1 2.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.1 KOS19609.1 - 2.3 8.6 12.8 23 5.3 0.1 4.0 2 2 1 3 3 3 0 Snapin/Pallidin Mhr1 PF12829.2 KOS19610.1 - 5.3e-24 83.8 0.0 1.2e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Sulfotransfer_3 PF13469.1 KOS19611.1 - 3.4e-05 24.8 0.5 5.9e-05 24.0 0.3 1.4 1 0 0 1 1 1 1 Sulfotransferase family PDT PF00800.13 KOS19612.1 - 4.8e-56 189.1 0.0 6.7e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 KOS19612.1 - 7.9e-05 22.0 0.0 0.00018 20.9 0.0 1.7 1 0 0 1 1 1 1 ACT domain ABM PF03992.11 KOS19613.1 - 0.0022 17.9 0.0 0.095 12.7 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase JAB PF01398.16 KOS19614.1 - 4.4e-07 29.6 0.5 2.9e-06 27.0 0.3 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Peptidase_C31 PF05410.8 KOS19614.1 - 0.06 13.2 0.0 1.8 8.4 0.0 2.4 1 1 1 2 2 2 0 Porcine arterivirus-type cysteine proteinase alpha PIG-X PF08320.7 KOS19615.1 - 2.2e-58 196.9 0.0 3.1e-58 196.4 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 Zn_clus PF00172.13 KOS19616.1 - 6.8e-08 32.2 7.3 1.5e-07 31.2 5.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KOS19616.1 - 0.0018 17.2 1.3 0.0029 16.5 0.6 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pkinase PF00069.20 KOS19617.1 - 1.2e-68 231.1 0.0 2.6e-68 229.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19617.1 - 3.5e-49 167.1 0.0 6.2e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KOS19617.1 - 3.8e-29 100.7 0.0 7.8e-29 99.6 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 KOS19617.1 - 9.7e-16 57.3 0.3 7.7e-15 54.5 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KOS19617.1 - 5.7e-15 55.2 0.1 1.1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KOS19617.1 - 1.2e-14 54.5 0.0 2.8e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 KOS19617.1 - 3.2e-08 32.9 0.0 0.00011 21.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.11 KOS19617.1 - 0.0066 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Relaxase PF03432.9 KOS19617.1 - 0.052 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Asp PF00026.18 KOS19618.1 - 1.5e-71 241.2 0.3 1.8e-71 240.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KOS19618.1 - 1.7e-11 44.3 0.9 4.4e-11 43.0 0.1 2.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KOS19618.1 - 1.6e-06 27.7 0.0 2.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KOS19618.1 - 0.0001 22.7 0.5 0.24 11.9 0.0 3.7 2 1 0 2 2 2 2 Aspartyl protease Zn_clus PF00172.13 KOS19619.1 - 0.00049 19.9 12.3 0.00098 18.9 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 KOS19619.1 - 0.013 14.7 0.0 0.013 14.7 0.0 2.2 3 0 0 3 3 3 0 Histone chaperone domain CHZ MFS_1 PF07690.11 KOS19620.1 - 2.8e-29 101.9 47.1 2.8e-29 101.9 32.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KOS19620.1 - 0.1 12.3 13.4 0.095 12.4 4.4 3.6 4 0 0 4 4 4 0 MFS_1 like family Abhydrolase_6 PF12697.2 KOS19621.1 - 0.01 15.7 8.2 0.021 14.7 5.7 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KOS19621.1 - 0.025 14.1 9.1 1.2 8.6 6.3 3.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 KOS19621.1 - 0.035 14.3 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PNTB PF02233.11 KOS19621.1 - 0.065 12.0 0.0 0.088 11.5 0.0 1.1 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit Abhydrolase_5 PF12695.2 KOS19621.1 - 0.069 12.9 3.5 0.49 10.1 2.5 2.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.6 KOS19621.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF3684 PF12449.3 KOS19622.1 - 8.2e-298 990.6 0.6 1.7e-195 651.8 0.0 4.4 1 1 3 4 4 4 4 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 KOS19622.1 - 3.1e-05 23.6 0.0 6.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fe_dep_repr_C PF02742.10 KOS19622.1 - 0.057 13.1 0.2 0.17 11.5 0.1 1.8 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain tRNA-synt_1 PF00133.17 KOS19623.1 - 9.8e-52 175.7 0.0 5.8e-28 97.2 0.1 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 KOS19623.1 - 7.8e-40 136.1 0.0 2.8e-39 134.3 0.0 2.0 2 1 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 KOS19623.1 - 4.1e-29 101.4 0.0 7.4e-21 74.2 0.0 4.1 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KOS19623.1 - 4.6e-11 42.6 0.0 8.4e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KOS19623.1 - 0.044 12.8 0.0 3.9 6.5 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain PQ-loop PF04193.9 KOS19624.1 - 8.1e-32 108.5 4.1 2.6e-15 55.7 1.4 2.5 2 0 0 2 2 2 2 PQ loop repeat GtrA PF04138.9 KOS19624.1 - 0.16 11.9 2.3 0.19 11.7 0.1 2.2 2 1 1 3 3 3 0 GtrA-like protein Fun_ATP-synt_8 PF05933.8 KOS19624.1 - 0.21 11.6 2.0 0.3 11.1 0.1 2.2 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) Mito_carr PF00153.22 KOS19625.1 - 1.4e-73 242.6 0.6 4.3e-25 87.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KOS19625.1 - 3.2e-16 57.3 0.1 2.4e-06 26.4 0.0 5.1 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 KOS19625.1 - 3.6e-16 59.0 4.3 1.2e-06 28.5 0.1 4.2 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.1 KOS19625.1 - 2.6e-15 54.8 0.6 5.9e-06 25.7 0.0 6.0 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.1 KOS19625.1 - 2.1e-13 49.6 0.2 0.0043 16.6 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KOS19625.1 - 7.8e-13 47.1 0.9 5.1e-05 22.4 0.1 4.6 4 0 0 4 4 4 3 EF hand Tyrosinase PF00264.15 KOS19626.1 - 1.8e-36 126.4 0.4 4.1e-36 125.2 0.2 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase ADC PF06314.6 KOS19627.1 - 0.018 14.3 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) Arf PF00025.16 KOS19628.1 - 3.8e-41 140.2 0.0 4.5e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KOS19628.1 - 4.4e-18 65.1 0.0 5.1e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS19628.1 - 6.8e-09 36.2 0.0 1.5e-08 35.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 KOS19628.1 - 2e-06 27.0 0.0 2.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KOS19628.1 - 3.2e-06 26.0 0.0 4.1e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.22 KOS19628.1 - 7.5e-05 22.2 0.0 0.00059 19.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KOS19628.1 - 0.0001 21.6 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KOS19628.1 - 0.00013 21.9 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KOS19628.1 - 0.029 14.1 0.1 0.094 12.5 0.1 1.7 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.13 KOS19628.1 - 0.053 12.8 0.1 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.4 KOS19628.1 - 0.16 11.4 0.1 0.57 9.6 0.0 1.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_pol_Rpb2_6 PF00562.23 KOS19629.1 - 1.8e-112 375.8 0.0 2.4e-112 375.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KOS19629.1 - 1.9e-28 98.7 0.0 3e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KOS19629.1 - 2e-27 95.8 0.0 3.1e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KOS19629.1 - 3.1e-25 87.7 0.0 1.1e-24 85.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 KOS19629.1 - 1.8e-20 72.5 0.0 5.3e-20 71.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 KOS19629.1 - 5.1e-15 55.5 0.0 6.1e-14 52.0 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KOS19629.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Beta_elim_lyase PF01212.16 KOS19630.1 - 4.4e-71 239.3 0.0 5.4e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KOS19630.1 - 1.2e-05 23.7 0.0 2.9e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KOS19630.1 - 0.0051 15.9 0.0 0.0095 15.0 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KOS19630.1 - 0.024 13.4 0.0 0.036 12.8 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Glyco_transf_17 PF04724.8 KOS19631.1 - 1e-39 136.5 0.0 1.4e-39 136.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 DPPIV_N PF00930.16 KOS19632.1 - 3.5e-104 348.1 0.0 4.4e-104 347.8 0.0 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KOS19632.1 - 2.3e-50 170.7 0.3 5e-50 169.6 0.2 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KOS19632.1 - 7.1e-09 35.5 0.3 1.9e-08 34.1 0.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 KOS19632.1 - 0.048 13.3 0.4 0.46 10.2 0.1 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat YbjQ_1 PF01906.12 KOS19633.1 - 5.3e-25 87.8 0.0 6.1e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Putative heavy-metal-binding MFS_1 PF07690.11 KOS19634.1 - 1.2e-36 126.1 39.8 1.2e-36 126.1 27.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS19634.1 - 3.2e-11 42.4 9.8 3.2e-11 42.4 6.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Clathrin PF00637.15 KOS19635.1 - 2.1e-203 666.0 41.0 1.2e-32 112.4 2.6 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 KOS19635.1 - 3.1e-31 107.0 0.6 1.3e-30 105.0 0.1 2.5 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 KOS19635.1 - 1.5e-26 90.8 1.3 0.0027 17.8 0.0 7.7 7 0 0 7 7 7 7 Clathrin propeller repeat TPR_7 PF13176.1 KOS19635.1 - 0.00036 20.1 9.3 2.8 7.9 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS19635.1 - 0.0089 16.3 2.5 20 5.6 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KOS19635.1 - 0.048 13.5 10.4 3.5 7.6 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 KOS19635.1 - 0.062 13.9 8.7 1.9e+02 3.1 0.0 8.1 9 1 1 10 10 10 0 Tetratricopeptide repeat F-box-like PF12937.2 KOS19637.1 - 1.4e-07 31.0 0.2 3.1e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS19637.1 - 0.00029 20.3 1.0 0.00052 19.5 0.7 1.4 1 0 0 1 1 1 1 F-box domain SWIRM PF04433.12 KOS19638.1 - 7.1e-14 51.6 0.0 1.2e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain TIP39 PF14980.1 KOS19638.1 - 2.5 7.7 5.1 0.74 9.4 0.2 2.3 2 0 0 2 2 2 0 TIP39 peptide GRIP PF01465.15 KOS19640.1 - 2.7e-15 55.5 0.0 5.9e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 GRIP domain Phage_GP20 PF06810.6 KOS19640.1 - 0.0019 17.6 4.3 0.0019 17.6 3.0 10.5 2 2 9 11 11 11 3 Phage minor structural protein GP20 TSC22 PF01166.13 KOS19640.1 - 0.011 15.6 1.2 0.011 15.6 0.8 9.8 6 2 5 11 11 11 0 TSC-22/dip/bun family Reo_sigmaC PF04582.7 KOS19640.1 - 0.042 13.0 45.5 0.14 11.2 1.7 6.9 2 2 6 8 8 8 0 Reovirus sigma C capsid protein DivIC PF04977.10 KOS19640.1 - 0.09 12.2 0.1 0.09 12.2 0.0 14.3 8 4 5 14 14 14 0 Septum formation initiator GAS PF13851.1 KOS19640.1 - 0.4 9.8 136.0 0.34 10.0 3.6 9.5 3 2 7 10 10 10 0 Growth-arrest specific micro-tubule binding adh_short PF00106.20 KOS19641.1 - 5.4e-23 81.7 0.7 1.5e-13 50.9 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KOS19641.1 - 1.3e-13 51.3 0.1 6.8e-06 26.0 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS19641.1 - 9.2e-09 35.2 0.3 1.5e-07 31.2 0.0 2.2 2 1 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 KOS19641.1 - 4.2e-05 23.6 0.0 0.00012 22.2 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KOS19641.1 - 0.0068 16.4 0.5 0.036 14.0 0.2 2.3 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KOS19641.1 - 0.026 13.9 0.8 0.45 9.9 0.0 2.4 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family DUF2296 PF10058.4 KOS19642.1 - 7e-19 67.3 0.1 1.2e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Nucleoplasmin PF03066.10 KOS19642.1 - 0.051 13.0 6.9 0.17 11.4 4.9 1.7 2 0 0 2 2 2 0 Nucleoplasmin NOA36 PF06524.7 KOS19642.1 - 0.17 11.1 5.4 0.29 10.3 3.7 1.4 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.7 KOS19642.1 - 1.3 8.0 15.6 2.7 7.0 10.8 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1183 PF06682.7 KOS19642.1 - 2 7.9 0.0 2 7.9 0.0 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1183) Nop14 PF04147.7 KOS19642.1 - 4.2 5.1 14.9 7 4.4 10.3 1.3 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 KOS19642.1 - 4.4 6.8 14.1 1.4 8.4 7.2 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Ribosomal_60s PF00428.14 KOS19642.1 - 4.9 7.6 17.5 2.1 8.8 4.6 2.6 1 1 1 2 2 2 0 60s Acidic ribosomal protein Ank_2 PF12796.2 KOS19643.1 - 1.2e-89 294.7 1.5 1.8e-22 79.4 0.1 6.8 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KOS19643.1 - 1.9e-84 273.5 10.8 6.9e-09 35.0 0.0 13.6 13 0 0 13 13 13 12 Ankyrin repeat Ank_4 PF13637.1 KOS19643.1 - 1.4e-69 229.3 18.1 4.8e-10 39.6 0.0 10.5 2 1 10 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS19643.1 - 3.2e-65 209.5 3.3 1.3e-05 24.9 0.0 13.4 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.1 KOS19643.1 - 3.3e-59 195.5 9.3 8.1e-09 35.4 0.1 11.6 2 2 10 12 12 12 10 Ankyrin repeats (many copies) F-box-like PF12937.2 KOS19643.1 - 0.0018 17.9 0.1 0.0045 16.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like Arg_repressor PF01316.16 KOS19643.1 - 0.04 13.4 0.1 30 4.2 0.0 3.7 4 0 0 4 4 4 0 Arginine repressor, DNA binding domain Asp_protease_2 PF13650.1 KOS19643.1 - 0.07 13.6 0.1 1.7 9.1 0.1 2.9 3 1 0 3 3 3 0 Aspartyl protease Pkinase PF00069.20 KOS19645.1 - 6.3e-41 140.2 0.0 5.9e-25 87.8 0.1 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19645.1 - 2.4e-15 56.3 0.2 1.2e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF1510 PF07423.6 KOS19645.1 - 0.062 12.6 1.8 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Shisa PF13908.1 KOS19645.1 - 0.099 12.8 0.1 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator STAG PF08514.6 KOS19646.1 - 1.7e-25 89.0 0.3 5.3e-25 87.4 0.2 1.9 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 KOS19646.1 - 1.4e-05 25.2 0.0 0.0015 18.7 0.0 3.8 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 KOS19646.1 - 0.009 16.0 0.1 32 4.9 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat DUF3439 PF11921.3 KOS19646.1 - 0.021 14.5 3.9 0.047 13.4 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 KOS19646.1 - 0.056 11.2 5.8 0.15 9.7 4.0 1.7 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 KOS19646.1 - 0.95 9.2 15.0 3 7.6 10.4 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 KOS19646.1 - 3.4 5.5 10.3 5 4.9 7.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RNA_pol_Rpc4 PF05132.9 KOS19647.1 - 9.3e-22 77.4 0.0 9.3e-22 77.4 0.0 3.7 4 0 0 4 4 4 1 RNA polymerase III RPC4 Mucin PF01456.12 KOS19647.1 - 0.0044 16.8 14.2 0.0044 16.8 9.9 1.9 2 0 0 2 2 2 1 Mucin-like glycoprotein Nucleoplasmin PF03066.10 KOS19647.1 - 0.0047 16.4 7.2 0.28 10.7 0.1 2.6 2 0 0 2 2 2 2 Nucleoplasmin DUF3439 PF11921.3 KOS19647.1 - 0.3 10.8 9.7 0.85 9.3 6.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 KOS19647.1 - 1.4 6.8 11.8 2.2 6.1 8.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 UreD PF01774.12 KOS19648.1 - 3.1e-52 177.0 0.0 3.8e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein DUF3433 PF11915.3 KOS19649.1 - 1.3e-19 70.1 0.8 1.9e-19 69.6 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) DUF3433 PF11915.3 KOS19650.1 - 7.5e-36 122.1 9.6 9.7e-24 83.3 1.4 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) SMI1_KNR4 PF09346.5 KOS19651.1 - 2e-34 118.3 0.0 3.4e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) DUF3613 PF12266.3 KOS19651.1 - 0.1 12.1 0.3 2.1 7.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) ArgJ PF01960.13 KOS19652.1 - 1.1e-141 471.8 0.0 1.2e-141 471.6 0.0 1.0 1 0 0 1 1 1 1 ArgJ family IGPD PF00475.13 KOS19653.1 - 8.8e-58 194.2 0.2 1.3e-57 193.7 0.1 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase TPR_2 PF07719.12 KOS19654.1 - 8.6e-28 93.9 18.8 0.00086 19.0 0.1 10.4 11 0 0 11 11 11 7 Tetratricopeptide repeat Apc3 PF12895.2 KOS19654.1 - 8.7e-27 93.0 14.3 1.8e-22 79.2 0.3 5.6 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KOS19654.1 - 8.9e-26 88.4 5.7 0.00018 21.0 0.2 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 KOS19654.1 - 4.1e-25 87.2 20.6 2e-07 30.5 0.0 7.5 5 2 0 6 6 6 5 TPR repeat TPR_19 PF14559.1 KOS19654.1 - 2e-22 79.2 16.8 0.0026 18.0 0.0 8.0 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 KOS19654.1 - 5.6e-20 71.0 15.3 2.3e-05 24.2 0.0 8.6 4 2 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 KOS19654.1 - 1e-16 61.0 24.7 3.5e-07 30.7 0.0 7.6 5 3 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 KOS19654.1 - 1.4e-16 59.4 21.2 0.023 15.3 0.1 10.3 5 4 5 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 KOS19654.1 - 2.4e-14 51.9 0.5 0.12 12.2 0.0 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.1 KOS19654.1 - 8.3e-09 35.0 14.2 0.23 11.4 0.1 8.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 KOS19654.1 - 1e-08 34.3 12.2 1.2 9.1 0.0 8.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.1 KOS19654.1 - 4.2e-07 30.0 6.3 2.5 8.7 0.1 8.0 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 KOS19654.1 - 6.2e-05 22.7 14.9 0.0058 16.4 0.0 6.3 8 0 0 8 8 7 1 Tetratricopeptide repeat Coatomer_E PF04733.9 KOS19654.1 - 0.00066 18.9 0.4 3.2 6.8 0.0 3.7 3 1 1 4 4 4 2 Coatomer epsilon subunit TPR_4 PF07721.9 KOS19654.1 - 0.0034 17.6 9.4 1.6 9.4 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 KOS19654.1 - 0.015 14.4 8.1 0.21 10.6 0.1 4.8 3 2 2 6 6 6 0 Tetratricopeptide repeat CI-B14_5a PF07347.7 KOS19654.1 - 0.041 13.6 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) RPN7 PF10602.4 KOS19654.1 - 0.054 12.8 0.5 7.4 5.9 0.0 3.7 2 1 1 3 3 3 0 26S proteasome subunit RPN7 DUF2388 PF09498.5 KOS19654.1 - 0.61 9.7 4.9 1.4 8.5 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2388) TPR_21 PF09976.4 KOS19654.1 - 1.7 8.5 13.2 7.4 6.4 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat FAT PF02259.18 KOS19655.1 - 4.4e-75 252.8 8.5 4.4e-75 252.8 5.9 1.8 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 KOS19655.1 - 4.8e-26 91.6 0.4 2.4e-25 89.3 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KOS19655.1 - 2.3e-08 33.2 0.2 5.4e-08 32.1 0.1 1.7 1 0 0 1 1 1 1 FATC domain TPR_8 PF13181.1 KOS19655.1 - 0.19 11.5 2.8 11 6.0 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Prefoldin_2 PF01920.15 KOS19656.1 - 2.2e-16 59.5 1.8 2.5e-16 59.3 1.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF148 PF02520.12 KOS19656.1 - 0.011 15.4 0.8 0.015 15.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 Prefoldin PF02996.12 KOS19656.1 - 0.045 13.4 0.2 0.046 13.3 0.2 1.3 1 0 0 1 1 1 0 Prefoldin subunit Cmc1 PF08583.5 KOS19657.1 - 2.2e-15 56.1 8.0 2.6e-15 55.9 5.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Gemini_AL2 PF01440.11 KOS19657.1 - 0.018 15.1 0.2 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 Geminivirus AL2 protein TPR_9 PF13371.1 KOS19657.1 - 0.082 12.7 0.5 0.13 12.0 0.4 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KOS19657.1 - 0.083 12.7 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat COX17 PF05051.8 KOS19657.1 - 0.14 12.1 4.4 2.5 8.1 0.6 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) MerR-DNA-bind PF09278.6 KOS19657.1 - 1 9.8 7.2 1.6 9.1 2.5 2.3 2 1 0 2 2 2 0 MerR, DNA binding GCK PF07802.6 KOS19657.1 - 1.5 9.0 6.1 5.4 7.2 3.5 1.9 1 1 0 1 1 1 0 GCK domain RRN3 PF05327.6 KOS19658.1 - 5.4e-164 546.4 0.0 5.4e-164 546.4 0.0 1.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.8 KOS19658.1 - 0.64 9.6 17.1 0.015 14.8 1.2 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region CBFD_NFYB_HMF PF00808.18 KOS19659.1 - 3e-30 104.0 0.8 3.9e-30 103.7 0.5 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KOS19659.1 - 1.4e-07 31.5 0.0 2.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KOS19659.1 - 0.00044 19.9 0.0 0.00059 19.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KOS19659.1 - 0.001 18.7 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 KOS19659.1 - 0.0097 16.1 0.3 0.061 13.6 0.0 1.9 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A HEAT_EZ PF13513.1 KOS19660.1 - 0.0053 17.2 0.3 3.7 8.1 0.0 3.8 3 0 0 3 3 3 2 HEAT-like repeat DivIC PF04977.10 KOS19661.1 - 0.01 15.3 1.3 0.021 14.3 0.9 1.4 1 0 0 1 1 1 0 Septum formation initiator Mon1 PF03164.9 KOS19663.1 - 2.4e-112 375.5 0.0 3.6e-112 374.9 0.0 1.2 1 0 0 1 1 1 1 Trafficking protein Mon1 Mito_fiss_reg PF05308.6 KOS19663.1 - 4.9 6.4 7.0 0.51 9.6 0.2 2.5 3 0 0 3 3 3 0 Mitochondrial fission regulator Granulin PF00396.13 KOS19664.1 - 0.044 13.8 26.7 0.14 12.2 3.3 3.6 2 1 1 3 3 3 0 Granulin IncA PF04156.9 KOS19664.1 - 0.058 12.9 0.2 0.099 12.2 0.1 1.3 1 0 0 1 1 1 0 IncA protein EphA2_TM PF14575.1 KOS19664.1 - 0.11 12.9 0.4 0.3 11.4 0.3 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Lustrin_cystein PF14625.1 KOS19664.1 - 0.37 10.9 22.5 0.1 12.6 6.6 2.9 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Pex16 PF08610.5 KOS19664.1 - 0.41 9.5 1.2 0.68 8.8 0.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) F-box-like PF12937.2 KOS19665.1 - 0.00028 20.5 0.1 0.00056 19.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS19665.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 F-box domain Prok-E2_A PF14457.1 KOS19667.1 - 0.0068 15.8 0.1 0.0086 15.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family A LSM PF01423.17 KOS19668.1 - 4.7e-18 64.4 0.1 6.2e-18 64.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain Trp_DMAT PF11991.3 KOS19668.1 - 0.086 12.0 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase ECH_C PF13766.1 KOS19669.1 - 1.2e-33 115.7 0.0 2.9e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KOS19669.1 - 3.5e-24 85.2 0.0 2.3e-23 82.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Glyco_hydro_76 PF03663.9 KOS19670.1 - 6e-120 401.0 14.1 8e-120 400.6 9.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DNA_ligase_A_M PF01068.16 KOS19671.1 - 8.6e-19 67.6 0.0 1.3e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain mRNA_cap_enzyme PF01331.14 KOS19671.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain DUF4048 PF13257.1 KOS19672.1 - 8.2e-09 35.4 6.2 1.7e-07 31.1 1.7 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4048) IncA PF04156.9 KOS19672.1 - 0.011 15.3 0.7 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 IncA protein Serglycin PF04360.7 KOS19672.1 - 0.067 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Serglycin MKT1_C PF12246.3 KOS19673.1 - 5.9e-57 192.4 0.0 9e-57 191.8 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KOS19673.1 - 1.8e-23 82.6 0.0 4.1e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 KOS19673.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 XPG I-region DUF3029 PF11230.3 KOS19673.1 - 0.12 10.5 0.0 3.2 5.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3029) DIOX_N PF14226.1 KOS19674.1 - 2.5e-22 79.5 0.0 5.5e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KOS19674.1 - 2e-16 60.1 0.0 3.8e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily G-alpha PF00503.15 KOS19675.1 - 1.6e-134 448.4 3.1 2e-134 448.1 2.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KOS19675.1 - 2.1e-15 56.3 1.5 2.3e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 KOS19675.1 - 9.3e-05 21.9 0.0 0.00041 19.8 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 KOS19675.1 - 0.0018 18.7 0.6 3.2 8.2 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 KOS19675.1 - 0.0052 15.9 2.6 0.27 10.3 0.0 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KOS19675.1 - 0.0098 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KOS19675.1 - 0.033 13.6 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.18 KOS19675.1 - 0.084 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family MMR_HSR1 PF01926.18 KOS19675.1 - 0.1 12.5 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KOS19675.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family D123 PF07065.9 KOS19676.1 - 4.4e-84 282.0 0.0 3.6e-83 279.1 0.0 2.2 1 1 0 1 1 1 1 D123 Nup188 PF10487.4 KOS19677.1 - 5.4e-26 90.8 1.9 2.8e-23 81.8 0.2 2.3 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 zf-Tim10_DDP PF02953.10 KOS19678.1 - 5.7e-20 70.3 1.2 9.5e-20 69.6 0.8 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KOS19678.1 - 0.11 11.9 2.7 0.47 9.9 1.9 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) RhoGAP PF00620.22 KOS19679.1 - 4.8e-37 126.8 0.0 7.9e-37 126.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF290 PF01060.18 KOS19679.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Transthyretin-like family Glyco_transf_22 PF03901.12 KOS19680.1 - 3.1e-75 253.7 2.5 4.7e-75 253.1 1.7 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family cwf21 PF08312.7 KOS19681.1 - 7.2e-18 64.1 13.6 1.8e-17 62.9 9.5 1.7 1 0 0 1 1 1 1 cwf21 domain Filament PF00038.16 KOS19681.1 - 0.0046 16.4 8.9 0.0052 16.3 6.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein GvpG PF05120.7 KOS19681.1 - 0.15 11.9 5.5 1.4 8.7 1.1 2.3 2 0 0 2 2 2 0 Gas vesicle protein G Use1 PF09753.4 KOS19682.1 - 0.00023 20.7 0.0 0.00042 19.8 0.0 1.4 1 0 0 1 1 1 1 Membrane fusion protein Use1 Synaptobrevin PF00957.16 KOS19682.1 - 3.2 7.4 5.5 10 5.7 0.6 2.3 2 0 0 2 2 2 0 Synaptobrevin IGPS PF00218.16 KOS19684.1 - 3e-96 321.3 0.1 5.3e-96 320.5 0.0 1.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 KOS19684.1 - 3.2e-50 170.2 0.0 6.7e-50 169.2 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I PRAI PF00697.17 KOS19684.1 - 3.7e-47 160.4 0.1 1.2e-43 149.0 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase QRPTase_C PF01729.14 KOS19684.1 - 5.1e-06 26.1 2.2 0.00016 21.2 0.1 3.1 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain Peptidase_C26 PF07722.8 KOS19684.1 - 2e-05 24.1 0.0 4.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 FMN_dh PF01070.13 KOS19684.1 - 0.019 13.8 0.2 0.042 12.6 0.1 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Abhydrolase_1 PF00561.15 KOS19685.1 - 7.9e-12 45.2 0.0 3.2e-11 43.2 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KOS19685.1 - 3.3e-11 43.4 0.0 8.7e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS19685.1 - 1.1e-05 25.2 0.0 0.00029 20.6 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.17 KOS19685.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Cutinase Pkinase PF00069.20 KOS19686.1 - 1.3e-68 230.9 0.0 2.6e-68 229.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19686.1 - 7e-36 123.6 0.0 1.1e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS19686.1 - 5.5e-05 22.2 0.0 8.8e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like WD40 PF00400.27 KOS19687.1 - 1.6e-37 125.9 0.7 3.8e-09 36.0 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KOS19687.1 - 9.8e-29 99.0 0.1 1.9e-28 98.1 0.1 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF4059 PF13268.1 KOS19687.1 - 0.19 11.9 0.0 0.4 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) XRN_N PF03159.13 KOS19688.1 - 6.2e-102 340.0 0.0 1.3e-101 339.0 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus SPC22 PF04573.7 KOS19689.1 - 4.4e-32 110.7 0.0 1.5e-22 79.6 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Pmp3 PF01679.12 KOS19692.1 - 2.8e-09 36.5 6.5 4.7e-09 35.8 4.5 1.4 1 1 0 1 1 1 1 Proteolipid membrane potential modulator zf-RanBP PF00641.13 KOS19693.1 - 1.8e-18 65.3 13.3 6.6e-11 41.1 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RNase_T PF00929.19 KOS19693.1 - 1.1e-06 29.0 0.0 1.6e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.17 KOS19693.1 - 2.8e-05 23.6 0.0 5.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS19693.1 - 0.0007 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 KOS19693.1 - 4.4 7.1 11.2 0.8 9.5 0.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon Transket_pyr PF02779.19 KOS19695.1 - 3.5e-63 212.2 0.0 5.8e-63 211.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KOS19695.1 - 5.1e-55 186.3 0.0 7.7e-55 185.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component MIF4G PF02854.14 KOS19696.1 - 2.7e-52 177.2 0.0 5.4e-52 176.2 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KOS19696.1 - 5e-21 74.3 0.2 2.7e-20 72.0 0.1 2.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Eno-Rase_FAD_bd PF07055.7 KOS19696.1 - 0.029 14.2 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain Mito_carr PF00153.22 KOS19697.1 - 1.2e-22 79.4 1.5 2e-10 40.2 0.0 2.6 2 1 0 2 2 2 2 Mitochondrial carrier protein SPT2 PF08243.6 KOS19698.1 - 3.4e-08 33.7 24.3 3e-06 27.5 8.3 2.3 1 1 1 2 2 2 2 SPT2 chromatin protein Ribosomal_L44 PF00935.14 KOS19698.1 - 0.47 10.4 3.6 2.5 8.1 0.2 3.1 2 1 1 3 3 3 0 Ribosomal protein L44 DUF3419 PF11899.3 KOS19699.1 - 5.9e-151 502.5 0.1 7.5e-151 502.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_26 PF13659.1 KOS19699.1 - 0.0026 17.7 0.4 3.5 7.6 0.0 3.7 2 2 0 2 2 2 2 Methyltransferase domain CybS PF05328.7 KOS19700.1 - 6.3e-52 174.7 0.0 7.8e-52 174.4 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 KOS19700.1 - 0.046 13.5 0.6 2 8.2 0.1 2.1 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit tRNA-synt_1b PF00579.20 KOS19701.1 - 1.8e-73 247.2 0.0 2.4e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NPR2 PF06218.6 KOS19702.1 - 2.3e-109 365.9 0.0 1.3e-91 307.4 0.0 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 SpoIISA_toxin PF14171.1 KOS19702.1 - 0.15 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF572 PF04502.8 KOS19703.1 - 1.6e-70 237.9 6.6 1.9e-70 237.6 4.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 KOS19703.1 - 0.0022 17.8 0.2 0.045 13.6 0.0 2.1 1 1 1 2 2 2 1 Benyvirus 14KDa protein zf-ribbon_3 PF13248.1 KOS19703.1 - 0.054 12.7 0.1 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-dskA_traR PF01258.12 KOS19703.1 - 0.1 12.3 1.5 0.42 10.3 0.1 2.5 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger DUF866 PF05907.8 KOS19703.1 - 0.37 10.2 1.9 5.4 6.4 0.1 2.2 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF866) Kin17_mid PF10357.4 KOS19704.1 - 1.3e-50 170.2 1.5 1.3e-50 170.2 1.0 2.0 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 KOS19704.1 - 0.00022 21.2 1.0 0.00051 20.0 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS19704.1 - 0.00063 19.8 2.0 0.0012 18.9 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KOS19704.1 - 0.033 14.3 0.2 0.033 14.3 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.7 KOS19704.1 - 0.07 11.6 2.8 0.096 11.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Spt4 PF06093.8 KOS19705.1 - 3.7e-33 113.2 0.0 4.6e-33 112.9 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TBCC PF07986.7 KOS19705.1 - 0.071 12.5 0.1 0.092 12.1 0.1 1.1 1 0 0 1 1 1 0 Tubulin binding cofactor C Coronavirus_5 PF05528.6 KOS19705.1 - 0.17 11.7 0.6 0.8 9.5 0.4 2.0 1 1 0 1 1 1 0 Coronavirus gene 5 protein Ig_3 PF13927.1 KOS19706.1 - 0.081 13.4 0.2 0.13 12.7 0.2 1.3 1 0 0 1 1 1 0 Immunoglobulin domain Metallophos PF00149.23 KOS19707.1 - 1.9e-39 135.1 0.0 2.6e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 KOS19707.1 - 1.3e-29 102.0 0.4 3.4e-29 100.6 0.3 1.8 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 KOS19707.1 - 3.9e-22 77.6 2.1 1.2e-15 56.8 0.3 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KOS19707.1 - 2.1e-16 58.7 0.4 0.00067 19.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS19707.1 - 4.1e-13 48.1 0.8 0.0063 16.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 KOS19707.1 - 0.00058 19.6 0.2 0.0022 17.7 0.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KOS19707.1 - 0.0021 18.6 2.6 1.2 9.8 0.4 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KOS19707.1 - 0.0025 18.1 0.2 1.2 9.5 0.0 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KOS19707.1 - 0.0028 17.7 1.2 0.88 9.9 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KOS19707.1 - 0.011 16.2 2.1 1.6 9.6 0.0 3.3 2 1 0 3 3 3 0 Tetratricopeptide repeat UPF0278 PF08745.6 KOS19707.1 - 0.031 13.5 0.1 0.049 12.8 0.1 1.2 1 0 0 1 1 1 0 UPF0278 family TPR_7 PF13176.1 KOS19707.1 - 0.042 13.6 0.0 0.15 11.9 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 KOS19707.1 - 0.084 13.3 0.2 9.3 6.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KOS19707.1 - 0.099 12.7 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KOS19707.1 - 0.12 12.3 0.1 1.9 8.4 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Es2 PF09751.4 KOS19708.1 - 6.1e-93 312.4 0.1 1.2e-92 311.4 0.0 1.5 1 1 0 1 1 1 1 Nuclear protein Es2 CTD PF12815.2 KOS19708.1 - 0.00082 19.7 7.4 0.0029 18.0 0.1 2.9 4 0 0 4 4 4 2 Spt5 C-terminal nonapeptide repeat binding Spt4 p450 PF00067.17 KOS19709.1 - 2.4e-45 154.9 0.0 3.1e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UPF0302 PF08864.5 KOS19709.1 - 0.23 11.2 0.5 2.3 8.0 0.1 2.4 2 1 1 3 3 3 0 UPF0302 domain p450 PF00067.17 KOS19711.1 - 2.9e-29 101.9 0.0 3.8e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 KOS19712.1 - 7e-15 54.5 1.1 7.9e-15 54.3 0.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF998 PF06197.8 KOS19712.1 - 0.27 10.5 15.1 1.8 7.8 10.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Flavi_glycoprot PF00869.15 KOS19712.1 - 0.4 9.6 1.4 0.55 9.1 1.0 1.1 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains Bot1p PF12298.3 KOS19713.1 - 3e-49 167.2 0.4 4.5e-49 166.6 0.1 1.5 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein HATPase_c PF02518.21 KOS19714.1 - 5.3e-21 74.4 0.0 1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KOS19714.1 - 5e-16 58.6 0.0 5.8e-15 55.2 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KOS19714.1 - 4.4e-09 36.2 0.0 2e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 KOS19714.1 - 1.2e-07 31.9 0.0 9.1e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 GAF domain Mucin PF01456.12 KOS19714.1 - 0.011 15.5 19.6 0.026 14.3 13.6 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein PEX11 PF05648.9 KOS19715.1 - 0.00013 21.3 0.4 0.0041 16.4 0.1 3.8 3 1 0 3 3 2 2 Peroxisomal biogenesis factor 11 (PEX11) DUF1510 PF07423.6 KOS19715.1 - 0.00078 18.8 6.9 0.0011 18.3 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) AIF_C PF14721.1 KOS19715.1 - 0.0025 18.0 2.2 0.0039 17.4 1.5 1.2 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Shisa PF13908.1 KOS19715.1 - 0.006 16.7 1.0 0.0095 16.1 0.7 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Protocadherin PF08374.6 KOS19715.1 - 0.01 15.4 1.2 0.014 14.9 0.8 1.1 1 0 0 1 1 1 0 Protocadherin TMEM51 PF15345.1 KOS19715.1 - 0.016 14.8 2.8 0.026 14.2 1.9 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 OATP PF03137.15 KOS19715.1 - 0.017 13.1 0.5 0.024 12.7 0.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FAM176 PF14851.1 KOS19715.1 - 0.034 13.8 1.6 0.049 13.3 1.1 1.2 1 0 0 1 1 1 0 FAM176 family Ctr PF04145.10 KOS19715.1 - 0.051 13.6 0.3 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Ctr copper transporter family RbsD_FucU PF05025.8 KOS19715.1 - 0.054 13.8 2.1 0.1 12.9 1.5 1.4 1 0 0 1 1 1 0 RbsD / FucU transport protein family SHR3_chaperone PF08229.6 KOS19715.1 - 0.055 12.4 7.5 0.091 11.7 5.2 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 EphA2_TM PF14575.1 KOS19715.1 - 0.056 13.8 0.8 0.056 13.8 0.6 2.2 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain G0-G1_switch_2 PF15103.1 KOS19715.1 - 0.08 13.1 3.6 0.14 12.3 2.5 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 Serinc PF03348.10 KOS19715.1 - 0.084 11.5 2.1 0.11 11.1 1.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Peroxin-13_N PF04088.8 KOS19715.1 - 0.089 12.7 1.9 0.25 11.3 1.0 1.8 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Herpes_UL4 PF03277.8 KOS19715.1 - 0.11 11.6 0.6 0.17 11.1 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL4 family zf-DHHC PF01529.15 KOS19715.1 - 0.15 11.4 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3260 PF11658.3 KOS19715.1 - 0.23 9.5 4.1 0.036 12.2 0.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3260) K_trans PF02705.11 KOS19715.1 - 0.25 9.6 0.4 0.33 9.2 0.3 1.1 1 0 0 1 1 1 0 K+ potassium transporter RRN3 PF05327.6 KOS19715.1 - 0.38 8.8 4.9 0.48 8.4 3.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_S49_N PF08496.5 KOS19715.1 - 0.42 10.3 9.7 0.63 9.8 6.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3987 PF13148.1 KOS19715.1 - 0.47 8.9 13.9 0.68 8.4 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) eIF3_subunit PF08597.5 KOS19715.1 - 0.49 9.9 21.8 0.69 9.4 15.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF106 PF01956.11 KOS19715.1 - 0.74 9.3 6.4 1.2 8.6 4.5 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Prog_receptor PF02161.10 KOS19715.1 - 1.2 7.8 8.3 1.9 7.2 5.8 1.3 1 0 0 1 1 1 0 Progesterone receptor YqfQ PF14181.1 KOS19715.1 - 1.3 9.0 16.6 2 8.4 11.5 1.3 1 0 0 1 1 1 0 YqfQ-like protein DUF912 PF06024.7 KOS19715.1 - 1.3 9.1 4.1 2 8.5 2.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FLO_LFY PF01698.11 KOS19715.1 - 1.9 7.2 10.6 2.5 6.8 7.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1980 PF09323.5 KOS19715.1 - 2.7 7.6 4.5 4.5 6.9 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Bap31 PF05529.7 KOS19715.1 - 2.8 7.3 8.0 4.3 6.7 5.6 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like BAF1_ABF1 PF04684.8 KOS19715.1 - 3.3 6.4 16.0 4.6 5.9 11.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DDHD PF02862.12 KOS19715.1 - 3.6 7.3 10.6 5.2 6.7 7.3 1.2 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 KOS19715.1 - 9.5 6.0 14.0 12 5.6 9.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family MFS_1 PF07690.11 KOS19716.1 - 3.1e-18 65.6 60.8 8.8e-16 57.5 33.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KOS19716.1 - 5 6.9 11.8 0.066 13.0 0.5 3.5 4 0 0 4 4 4 0 MFS_1 like family DUF2530 PF10745.4 KOS19716.1 - 8.8 6.3 8.7 2.3 8.2 0.3 3.5 3 2 0 3 3 3 0 Protein of unknown function (DUF2530) Sugar_tr PF00083.19 KOS19717.1 - 2.5e-17 62.6 0.1 2.4e-10 39.6 0.0 2.8 1 1 1 2 2 2 2 Sugar (and other) transporter Bd3614-deam PF14439.1 KOS19717.1 - 0.058 13.2 0.9 0.11 12.4 0.7 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase FAD_binding_4 PF01565.18 KOS19718.1 - 2.9e-18 65.6 0.1 5.7e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KOS19718.1 - 9.8e-13 47.7 0.4 3.6e-12 45.9 0.1 2.0 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 KOS19718.1 - 0.024 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding LysM PF01476.15 KOS19721.1 - 3.4e-14 52.4 0.4 2.7e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 LysM domain Mucin PF01456.12 KOS19721.1 - 0.0099 15.6 23.3 0.015 15.1 16.2 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Pex14_N PF04695.8 KOS19721.1 - 0.025 14.6 3.6 0.031 14.3 2.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DHHW PF14286.1 KOS19721.1 - 0.069 12.4 0.8 0.08 12.2 0.6 1.1 1 0 0 1 1 1 0 DHHW protein Alpha_GJ PF03229.8 KOS19721.1 - 0.085 13.1 13.3 0.14 12.5 9.2 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J Dicty_REP PF05086.7 KOS19721.1 - 0.11 10.2 3.4 0.12 10.1 2.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sporozoite_P67 PF05642.6 KOS19721.1 - 0.14 10.0 11.4 0.15 9.9 7.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_capsid PF06112.6 KOS19721.1 - 0.18 11.8 8.2 0.23 11.5 5.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PRCC PF10253.4 KOS19721.1 - 0.21 12.2 6.6 0.28 11.8 4.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SSP160 PF06933.6 KOS19721.1 - 3.7 5.3 18.9 4.4 5.1 13.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Med3 PF11593.3 KOS19721.1 - 3.9 6.6 12.7 4.7 6.3 8.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GVQW PF13900.1 KOS19723.1 - 0.026 14.5 0.2 3 7.9 0.0 2.7 2 0 0 2 2 2 0 Putative binding domain SET PF00856.23 KOS19725.1 - 1.1e-21 77.8 0.3 1.1e-21 77.8 0.2 4.0 3 2 0 3 3 3 1 SET domain SRI PF08236.6 KOS19725.1 - 2.9e-20 72.0 1.5 2.9e-20 72.0 1.1 1.9 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 KOS19725.1 - 1.2e-05 24.6 0.1 2.6e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.21 KOS19725.1 - 0.0011 18.7 0.2 0.0022 17.8 0.1 1.5 1 0 0 1 1 1 1 WW domain DUF4544 PF15077.1 KOS19725.1 - 0.21 11.0 3.5 0.5 9.8 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) DUF2431 PF10354.4 KOS19726.1 - 2.4e-44 151.2 0.4 1.5e-29 103.0 0.0 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF2431) Pox_Ag35 PF03286.9 KOS19726.1 - 0.0057 16.2 10.4 0.0057 16.2 7.2 3.0 2 1 0 2 2 2 1 Pox virus Ag35 surface protein Peptidase_U57 PF05582.7 KOS19726.1 - 0.92 8.4 11.2 0.85 8.5 7.0 1.4 1 1 0 1 1 1 0 YabG peptidase U57 Glyco_hydro_18 PF00704.23 KOS19727.1 - 1.3e-42 146.4 1.5 1.9e-42 145.9 0.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 KOS19727.1 - 1.2e-17 63.5 1.1 5.7e-17 61.4 0.1 2.6 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.15 KOS19727.1 - 3.4e-09 36.4 0.0 0.00077 19.3 0.0 2.8 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KOS19727.1 - 0.00035 20.4 2.8 0.00035 20.4 1.9 3.6 3 0 0 3 3 3 1 Chitin recognition protein Aminotran_3 PF00202.16 KOS19728.1 - 3.8e-88 295.5 0.0 4.4e-88 295.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Mur_ligase_M PF08245.7 KOS19729.1 - 6.1e-05 23.1 0.1 0.00041 20.4 0.1 2.1 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 KOS19729.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain GFA PF04828.9 KOS19730.1 - 5.8e-12 45.3 3.3 1.1e-06 28.5 0.0 2.6 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S27 PF01599.14 KOS19730.1 - 0.11 12.2 0.2 0.11 12.2 0.2 2.8 4 0 0 4 4 4 0 Ribosomal protein S27a Ribosomal_S17 PF00366.15 KOS19731.1 - 1.4e-30 105.1 0.9 2e-30 104.6 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.1 KOS19732.1 - 3e-61 207.6 54.3 1.8e-44 152.0 14.9 3.0 1 1 1 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 DUF2167 PF09935.4 KOS19732.1 - 0.011 14.5 0.5 0.018 13.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) DUF3835 PF12927.2 KOS19733.1 - 1.5e-14 54.6 0.4 1.5e-14 54.6 0.3 4.9 4 2 1 5 5 5 1 Domain of unknown function (DUF3835) CBFD_NFYB_HMF PF00808.18 KOS19733.1 - 0.047 13.7 0.3 0.13 12.3 0.2 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SSV1_ORF_D-335 PF07935.6 KOS19733.1 - 0.053 13.2 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 ORF D-335-like protein DUF1719 PF08224.6 KOS19734.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Bcr-Abl_Oligo PF09036.5 KOS19734.1 - 0.15 12.0 2.2 0.46 10.4 0.2 2.5 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF1713 PF08213.6 KOS19735.1 - 2.3e-12 46.2 21.4 3.9e-12 45.5 14.8 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 KOS19735.1 - 0.0042 17.0 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial protein Pet20 GNAT_acetyltr_2 PF13718.1 KOS19736.1 - 1.7e-81 272.2 0.0 3.2e-81 271.3 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KOS19736.1 - 3.5e-65 218.9 0.0 1.3e-64 217.0 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KOS19736.1 - 2.9e-37 126.2 0.0 6.8e-37 125.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KOS19736.1 - 1.4e-30 105.3 0.4 4.1e-30 103.8 0.3 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 KOS19736.1 - 0.01 15.9 0.0 0.034 14.3 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS19736.1 - 0.048 13.7 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Spc7 PF08317.6 KOS19737.1 - 1.9e-106 355.4 2.7 2.7e-106 354.9 1.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 KOS19737.1 - 4.2e-18 64.7 0.2 8.9e-18 63.7 0.1 1.5 1 0 0 1 1 1 1 Spc7_C2 APG6 PF04111.7 KOS19737.1 - 0.17 10.9 9.0 0.096 11.7 3.8 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 Not3 PF04065.10 KOS19737.1 - 0.42 9.8 7.0 1.2 8.3 4.2 2.1 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component ADIP PF11559.3 KOS19737.1 - 0.58 10.0 8.7 0.39 10.6 1.3 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YlqD PF11068.3 KOS19737.1 - 1 9.3 8.7 0.16 12.0 0.6 2.8 2 1 1 3 3 3 0 YlqD protein COG2 PF06148.6 KOS19737.1 - 3.6 7.4 8.6 1.6 8.6 0.7 2.7 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.1 KOS19737.1 - 3.7 5.8 7.1 11 4.2 4.8 1.6 1 1 0 1 1 1 0 AAA domain IncA PF04156.9 KOS19737.1 - 4.9 6.7 20.0 1.3 8.5 10.3 2.4 2 1 0 2 2 2 0 IncA protein DivIC PF04977.10 KOS19737.1 - 9.8 5.7 8.3 2.4 7.7 2.0 2.4 1 1 1 2 2 2 0 Septum formation initiator Mpv17_PMP22 PF04117.7 KOS19738.1 - 9.2e-28 95.6 7.5 1.4e-27 95.1 5.2 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Cys_Met_Meta_PP PF01053.15 KOS19739.1 - 2.7e-57 193.7 0.0 7.6e-44 149.5 0.0 2.6 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KOS19739.1 - 0.14 10.8 0.0 0.27 9.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Secretin_N_2 PF07655.8 KOS19739.1 - 0.28 11.5 4.7 1.1 9.7 3.0 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain Polysacc_deac_1 PF01522.16 KOS19740.1 - 5.3e-19 68.0 0.0 8.1e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase GFRP PF06399.8 KOS19740.1 - 0.019 14.5 0.1 1.6 8.3 0.0 3.0 3 0 0 3 3 3 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Polysacc_deac_2 PF04748.8 KOS19740.1 - 0.038 12.9 0.1 0.1 11.5 0.0 1.8 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase OppC_N PF12911.2 KOS19740.1 - 0.38 10.1 4.2 0.89 8.9 2.9 1.7 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C zf-UDP PF14569.1 KOS19742.1 - 0.083 12.6 6.4 0.14 11.9 4.4 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_3 PF13920.1 KOS19742.1 - 1.8 8.2 13.4 3 7.5 9.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 KOS19742.1 - 5.1 6.9 11.8 7.8 6.3 1.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_2 PF13639.1 KOS19742.1 - 7.4 6.4 11.8 12 5.8 8.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 KOS19742.1 - 8.6 6.0 12.3 18 4.9 8.5 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain EF-hand_1 PF00036.27 KOS19743.1 - 5e-26 87.9 5.8 3.6e-06 25.8 0.0 5.4 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 KOS19743.1 - 9.6e-25 86.5 3.4 3.2e-09 36.7 0.1 3.7 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KOS19743.1 - 7.6e-21 72.0 4.4 0.00099 18.8 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 KOS19743.1 - 4.7e-17 61.3 9.3 1.3e-06 27.9 0.1 4.8 3 1 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 KOS19743.1 - 9.2e-17 59.5 4.3 0.0011 18.2 0.2 4.5 4 0 0 4 4 4 4 EF hand TFIIA PF03153.8 KOS19743.1 - 0.13 12.1 22.9 0.17 11.7 15.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.11 KOS19743.1 - 1.8 8.3 7.5 2.2 8.0 5.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ChaC PF04752.7 KOS19744.1 - 2.3e-36 125.3 0.0 3.3e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Glycophorin_A PF01102.13 KOS19745.1 - 1.1 9.0 9.8 0.57 9.9 1.3 2.5 2 0 0 2 2 2 0 Glycophorin A WD40 PF00400.27 KOS19746.1 - 2.2e-24 84.3 8.5 4.9e-06 26.2 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KOS19746.1 - 0.0015 16.7 3.7 0.0029 15.8 0.9 2.3 1 1 1 2 2 2 1 Nucleoporin Nup120/160 CDC45 PF02724.9 KOS19746.1 - 9.9 4.0 25.6 4.6 5.1 0.1 2.2 2 0 0 2 2 2 0 CDC45-like protein HA2 PF04408.18 KOS19747.1 - 3.8e-26 91.0 3.5 9.5e-26 89.7 0.0 3.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KOS19747.1 - 2.2e-25 88.7 0.0 7.3e-24 83.7 0.0 2.9 3 0 0 3 3 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KOS19747.1 - 1.4e-13 50.4 0.0 3.7e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS19747.1 - 3.8e-08 32.9 0.0 8.7e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KOS19747.1 - 8.5e-05 22.7 0.0 0.00021 21.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KOS19747.1 - 0.00075 19.3 0.0 0.33 10.7 0.0 3.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 KOS19747.1 - 0.001 18.0 0.0 0.0025 16.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 KOS19747.1 - 0.002 17.1 0.0 0.0041 16.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KOS19747.1 - 0.0049 16.0 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 KaiC Flavi_DEAD PF07652.9 KOS19747.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Arch_ATPase PF01637.13 KOS19747.1 - 0.02 14.6 0.0 0.08 12.6 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 KOS19747.1 - 0.023 14.9 0.3 0.11 12.8 0.0 2.3 2 0 0 2 2 1 0 ABC transporter AAA_14 PF13173.1 KOS19747.1 - 0.028 14.3 0.2 0.2 11.5 0.2 2.2 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KOS19747.1 - 0.039 13.4 0.1 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain GAD PF02938.9 KOS19747.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 GAD domain NACHT PF05729.7 KOS19747.1 - 0.088 12.4 0.7 0.59 9.7 0.1 2.5 3 0 0 3 3 3 0 NACHT domain AAA_25 PF13481.1 KOS19747.1 - 0.093 12.1 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KOS19747.1 - 0.1 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Acylphosphatase PF00708.13 KOS19748.1 - 9e-25 86.6 0.0 9.7e-25 86.4 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase WD40 PF00400.27 KOS19749.1 - 4.5e-11 42.1 8.9 2.2e-05 24.1 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat NYD-SP28_assoc PF14775.1 KOS19749.1 - 0.11 12.2 0.8 0.34 10.6 0.4 2.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain Tim17 PF02466.14 KOS19752.1 - 3.4e-24 85.3 6.0 3.4e-24 85.3 4.2 1.7 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Complex1_LYR_1 PF13232.1 KOS19755.1 - 3.5e-21 75.1 3.3 4.3e-21 74.8 2.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KOS19755.1 - 3.5e-19 68.3 3.6 4.5e-19 67.9 2.5 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KOS19755.1 - 0.0022 18.4 0.4 0.0026 18.2 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like PilP PF04351.8 KOS19755.1 - 0.0053 16.6 0.2 0.0066 16.3 0.1 1.0 1 0 0 1 1 1 1 Pilus assembly protein, PilP SSFA2_C PF14723.1 KOS19755.1 - 0.02 14.6 0.2 0.025 14.2 0.1 1.1 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus IL28A PF15177.1 KOS19755.1 - 0.11 11.9 0.1 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Interleukin-28A Toxin_43 PF15604.1 KOS19755.1 - 0.24 11.4 2.5 0.29 11.1 1.8 1.2 1 0 0 1 1 1 0 Putative toxin 43 OMP_b-brl_2 PF13568.1 KOS19757.1 - 0.9 9.3 18.3 0.33 10.7 1.1 3.4 2 2 1 3 3 3 0 Outer membrane protein beta-barrel domain Yae1_N PF09811.4 KOS19757.1 - 9.1 5.8 13.6 5.5 6.6 0.6 3.5 2 1 1 3 3 3 0 Essential protein Yae1, N terminal LCCL PF03815.14 KOS19758.1 - 6.4e-21 74.1 0.1 1.1e-20 73.4 0.1 1.3 1 0 0 1 1 1 1 LCCL domain Abhydrolase_2 PF02230.11 KOS19759.1 - 0.0088 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KOS19759.1 - 0.03 14.1 0.1 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS19759.1 - 0.037 13.7 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Asparaginase PF00710.15 KOS19760.1 - 2.6e-104 348.4 0.0 3.6e-104 348.0 0.0 1.2 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 KOS19760.1 - 1.4e-15 57.3 0.5 2.8e-15 56.4 0.3 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KOS19760.1 - 1.9e-15 55.7 1.8 1.4e-07 30.9 0.2 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KOS19760.1 - 5.4e-10 39.5 0.1 5.7e-05 23.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS19760.1 - 7.8e-09 34.9 0.2 0.0024 17.9 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KOS19760.1 - 6e-07 29.5 0.6 2.9e-05 24.1 0.2 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) USP7_ICP0_bdg PF12436.3 KOS19761.1 - 1.3e-82 276.7 0.0 2.7e-81 272.4 0.0 2.3 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KOS19761.1 - 7.8e-77 257.4 6.9 1.3e-74 250.2 0.7 4.6 5 0 0 5 5 5 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 KOS19761.1 - 7e-57 192.5 1.7 1.1e-56 191.9 1.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS19761.1 - 2.3e-28 99.4 0.2 4.1e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KOS19761.1 - 2.7e-12 47.0 0.4 5.7e-11 42.6 0.0 3.1 3 0 0 3 3 3 1 MATH domain YukD PF08817.5 KOS19761.1 - 0.004 17.6 0.0 7.2 7.2 0.0 3.1 3 0 0 3 3 3 2 WXG100 protein secretion system (Wss), protein YukD DUF4089 PF13318.1 KOS19762.1 - 0.04 14.2 0.6 0.097 12.9 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4089) Zip PF02535.17 KOS19762.1 - 0.63 8.9 5.5 1.1 8.1 3.8 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.20 KOS19763.1 - 9.3e-64 215.0 0.0 1.1e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19763.1 - 4.4e-30 104.6 0.0 5.8e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS19763.1 - 0.0049 15.8 0.0 0.012 14.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like PQ-loop PF04193.9 KOS19764.1 - 5.3e-16 57.9 0.7 1.4e-10 40.5 0.1 2.7 2 0 0 2 2 2 2 PQ loop repeat TGT PF01702.13 KOS19765.1 - 1.5e-33 116.0 0.0 2.2e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase 6PF2K PF01591.13 KOS19765.1 - 0.0022 17.0 0.0 0.0033 16.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase MTHFR PF02219.12 KOS19766.1 - 9.9e-96 320.1 0.0 4.7e-94 314.6 0.0 2.2 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase ORC6 PF05460.8 KOS19767.1 - 7.8 5.4 7.2 26 3.7 5.0 1.7 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Asp PF00026.18 KOS19768.1 - 8.9e-64 215.7 0.7 1.1e-63 215.4 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KOS19768.1 - 3.1e-09 36.9 0.1 8.1e-09 35.6 0.1 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KOS19768.1 - 0.0056 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Mto2_bdg PF12808.2 KOS19768.1 - 0.17 12.0 0.7 0.3 11.2 0.5 1.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PPTA PF01239.17 KOS19769.1 - 8.8e-10 37.5 7.7 0.029 13.7 0.3 4.6 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat DUF3414 PF11894.3 KOS19770.1 - 0 1336.5 0.0 0 1336.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) PI3_PI4_kinase PF00454.22 KOS19772.1 - 6.8e-46 156.6 0.0 1e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KOS19772.1 - 4e-17 62.2 2.2 7.1e-17 61.4 1.5 1.3 1 0 0 1 1 1 1 FAT domain FATC PF02260.15 KOS19772.1 - 1.5e-12 46.7 0.1 3.3e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 FATC domain Gln-synt_C PF00120.19 KOS19773.1 - 3e-58 197.0 0.0 3.6e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KOS19773.1 - 9.7e-20 69.9 0.0 1.7e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Kinetochor_Ybp2 PF08568.5 KOS19774.1 - 1.1e-80 271.6 0.0 8.5e-54 182.8 0.0 2.0 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin DNA_pol_A PF00476.15 KOS19775.1 - 5.2e-97 324.8 0.0 7.5e-97 324.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A ABC_membrane PF00664.18 KOS19776.1 - 1.4e-91 306.7 38.3 6.3e-50 170.1 7.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KOS19776.1 - 7.5e-69 230.3 0.9 3.9e-33 114.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 KOS19776.1 - 4.5e-14 52.2 0.0 2.3e-05 23.7 0.0 3.4 1 1 2 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KOS19776.1 - 8.9e-10 38.9 0.1 0.77 9.6 0.0 4.3 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KOS19776.1 - 3.9e-09 35.8 1.7 0.00018 20.9 0.3 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 KOS19776.1 - 2.4e-08 33.0 2.2 0.0046 15.6 0.1 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KOS19776.1 - 4.9e-08 33.1 0.7 0.0072 16.3 0.0 3.2 3 0 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 KOS19776.1 - 1.1e-06 29.4 0.2 0.12 13.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KOS19776.1 - 5.7e-06 25.6 0.0 0.15 11.1 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KOS19776.1 - 0.00018 21.3 1.0 0.87 9.5 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 KOS19776.1 - 0.0011 18.4 5.1 0.6 9.4 0.1 3.4 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.1 KOS19776.1 - 0.0011 19.0 4.8 1.8 8.7 0.2 4.0 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KOS19776.1 - 0.0016 18.7 0.0 2.7 8.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KOS19776.1 - 0.0018 18.1 0.0 2.7 7.9 0.0 3.5 3 1 1 4 4 3 1 AAA domain AAA_33 PF13671.1 KOS19776.1 - 0.0026 17.6 0.0 3.1 7.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.15 KOS19776.1 - 0.0051 15.5 0.0 1.4 7.5 0.0 2.4 2 1 0 2 2 2 1 G-protein alpha subunit AAA_5 PF07728.9 KOS19776.1 - 0.0067 16.1 0.3 7.4 6.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KOS19776.1 - 0.01 15.8 2.4 0.65 9.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 KOS19776.1 - 0.028 14.5 0.1 17 5.6 0.0 3.8 4 0 0 4 4 3 0 RNA helicase DUF87 PF01935.12 KOS19776.1 - 0.036 13.8 3.2 4.6 6.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 MobB PF03205.9 KOS19776.1 - 0.08 12.6 0.2 15 5.2 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KOS19776.1 - 0.088 12.7 0.1 7.4 6.5 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 KOS19776.1 - 0.098 13.1 0.0 8.5 6.9 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 KOS19776.1 - 0.11 11.9 3.5 14 4.9 0.3 3.7 4 0 0 4 4 4 0 AAA-like domain AAA_23 PF13476.1 KOS19776.1 - 0.13 12.5 2.4 4.3 7.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain zf-C3HC4_3 PF13920.1 KOS19777.1 - 2.1e-11 43.3 9.6 3e-11 42.7 6.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS19777.1 - 6.5e-09 35.4 10.5 9.9e-09 34.8 7.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KOS19777.1 - 8.5e-09 35.3 10.4 1.3e-08 34.6 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS19777.1 - 7.9e-06 25.4 11.1 1.2e-05 24.8 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS19777.1 - 1.3e-05 24.8 10.1 2.1e-05 24.1 7.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KOS19777.1 - 3e-05 23.7 4.4 5.9e-05 22.8 3.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KOS19777.1 - 0.0021 17.5 7.1 0.0037 16.8 4.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KOS19777.1 - 0.0042 16.9 8.4 0.0071 16.1 5.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KOS19777.1 - 0.052 13.6 4.8 0.095 12.8 3.3 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KOS19777.1 - 0.069 12.8 6.3 0.16 11.7 4.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 KOS19777.1 - 0.12 11.9 6.7 0.58 9.7 4.6 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 FYVE_2 PF02318.11 KOS19777.1 - 0.25 11.2 2.3 0.41 10.5 1.6 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger FANCL_C PF11793.3 KOS19777.1 - 4.5 7.3 8.7 4.6e+02 0.8 6.1 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain HEAT PF02985.17 KOS19778.1 - 2.5e-44 145.3 19.0 0.0028 17.6 0.1 13.2 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 KOS19778.1 - 9.8e-31 105.8 2.5 9.2e-08 32.2 0.0 7.8 3 3 5 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.2 KOS19778.1 - 7e-12 45.5 4.1 0.0043 17.4 0.1 7.7 5 2 3 9 9 9 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KOS19778.1 - 9.7e-10 37.3 6.8 0.00064 18.1 0.1 4.9 4 1 1 5 5 5 3 Adaptin N terminal region HEAT_EZ PF13513.1 KOS19778.1 - 1.2e-09 38.3 10.2 0.055 13.9 0.0 8.5 7 2 3 10 10 10 2 HEAT-like repeat CLASP_N PF12348.3 KOS19778.1 - 2.6e-05 23.6 2.2 1 8.6 0.0 4.6 4 3 1 5 5 5 3 CLASP N terminal DUF2435 PF10363.4 KOS19778.1 - 0.00017 21.4 7.3 0.023 14.6 0.1 4.9 4 1 1 5 5 5 1 Protein of unknown function (DUF2435) RIX1 PF08167.7 KOS19778.1 - 0.0037 16.9 0.5 0.46 10.1 0.0 3.9 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis Arm PF00514.18 KOS19778.1 - 0.014 15.2 3.0 2.6 8.0 0.0 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Sp100 PF03172.8 KOS19778.1 - 0.061 13.2 0.0 0.24 11.3 0.0 2.1 1 0 0 1 1 1 0 Sp100 domain Cnd3 PF12719.2 KOS19778.1 - 0.093 11.6 1.4 0.83 8.5 0.1 2.9 3 1 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain MadL PF03817.8 KOS19778.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Malonate transporter MadL subunit Sp38 PF07354.7 KOS19778.1 - 0.15 10.6 0.0 1.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) Cnd1 PF12717.2 KOS19778.1 - 0.65 9.8 9.1 4.6 7.0 0.4 5.1 4 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 KOS19778.1 - 1.4 7.1 5.4 0.83 7.8 0.1 2.8 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit bZIP_2 PF07716.10 KOS19779.1 - 2.2e-07 30.5 14.7 6.4e-07 29.0 10.2 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KOS19779.1 - 0.0056 16.6 15.4 0.0056 16.6 10.7 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 KOS19779.1 - 0.029 14.6 10.3 0.029 14.6 7.1 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Methyltransf_29 PF03141.11 KOS19779.1 - 0.16 10.2 0.7 0.31 9.3 0.0 1.7 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase V_ATPase_I PF01496.14 KOS19779.1 - 0.39 8.5 1.7 0.53 8.0 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Swi3 PF07962.7 KOS19780.1 - 2.1e-17 62.5 0.5 6.5e-17 60.9 0.0 2.0 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 DUF1754 PF08555.5 KOS19780.1 - 0.42 11.2 3.8 0.25 11.9 0.6 2.0 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF3499 PF12005.3 KOS19780.1 - 7.2 6.8 11.4 9.5 6.4 4.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3499) Surfac_D-trimer PF09006.6 KOS19781.1 - 0.0027 17.3 1.4 0.15 11.8 0.2 3.0 2 1 1 3 3 3 1 Lung surfactant protein D coiled-coil trimerisation MbeD_MobD PF04899.7 KOS19781.1 - 0.029 14.2 0.2 0.092 12.6 0.1 1.9 1 1 0 1 1 1 0 MbeD/MobD like BBP1_C PF15272.1 KOS19781.1 - 0.076 12.5 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal eIF-6 PF01912.13 KOS19782.1 - 1.3e-83 278.9 1.2 1.8e-83 278.5 0.8 1.2 1 0 0 1 1 1 1 eIF-6 family p450 PF00067.17 KOS19783.1 - 8.2e-41 139.9 0.0 2.3e-37 128.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Methyltransf_2 PF00891.13 KOS19783.1 - 0.0094 15.1 0.1 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase eIF-5_eIF-2B PF01873.12 KOS19785.1 - 1.5e-37 128.0 0.0 4.6e-37 126.4 0.0 1.8 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 KOS19785.1 - 5e-25 87.2 0.9 1.6e-24 85.6 0.4 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Asp PF00026.18 KOS19787.1 - 3.9e-66 223.4 0.1 4.8e-66 223.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KOS19787.1 - 2.7e-07 31.0 1.3 0.00023 21.6 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease TAXi_N PF14543.1 KOS19787.1 - 1.4e-06 28.3 0.0 9.8e-06 25.6 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KOS19787.1 - 0.0013 18.3 0.0 0.0039 16.7 0.0 1.9 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Microtub_assoc PF07989.6 KOS19788.1 - 0.068 13.0 10.9 0.017 14.9 5.0 1.9 2 0 0 2 2 2 0 Microtubule associated V_ATPase_I PF01496.14 KOS19788.1 - 0.48 8.2 2.2 0.7 7.6 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PRKCSH PF07915.8 KOS19789.1 - 5.3e-18 65.5 0.0 1.5e-17 64.1 0.0 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF4604 PF15377.1 KOS19789.1 - 1.9 8.6 11.1 0.072 13.3 3.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) zf-C2H2_6 PF13912.1 KOS19790.1 - 0.00022 21.0 0.7 0.00022 21.0 0.5 1.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KOS19790.1 - 0.0023 18.1 1.6 0.0023 18.1 1.1 2.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS19790.1 - 0.006 16.8 5.1 0.023 15.0 0.7 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KOS19790.1 - 0.0091 16.1 0.2 0.021 14.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS19790.1 - 0.016 15.4 0.3 0.042 14.0 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KOS19791.1 - 1.9e-06 27.8 4.3 0.015 15.6 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS19791.1 - 0.00062 19.9 8.8 0.15 12.4 0.4 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger Sld5 PF05916.6 KOS19793.1 - 3e-10 40.3 0.0 4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Rxt3 PF08642.5 KOS19794.1 - 5.6e-24 84.6 1.6 2.6e-23 82.4 0.0 2.6 3 0 0 3 3 3 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 KOS19794.1 - 0.00024 21.0 0.0 0.0017 18.2 0.0 2.2 2 0 0 2 2 2 1 LCCL domain RAB3GAP2_N PF14655.1 KOS19794.1 - 0.79 8.6 5.2 1.4 7.8 3.6 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.9 KOS19794.1 - 6.4 6.4 16.8 2.7 7.6 5.1 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SprT-like PF10263.4 KOS19796.1 - 7e-12 45.2 0.0 1.1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Spore_YtfJ PF09579.5 KOS19796.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) F-box-like PF12937.2 KOS19797.1 - 3.2e-12 45.9 1.7 6.3e-12 45.0 1.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS19797.1 - 1.2e-09 37.6 1.3 2.2e-09 36.7 0.9 1.5 1 0 0 1 1 1 1 F-box domain DUF3439 PF11921.3 KOS19797.1 - 1.3 8.8 7.9 2.6 7.8 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2457 PF10446.4 KOS19797.1 - 3.1 6.4 25.7 3.2 6.3 11.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 KOS19797.1 - 5.7 6.4 12.2 1.9 8.0 4.9 2.3 2 0 0 2 2 2 0 Nucleoplasmin Epimerase PF01370.16 KOS19799.1 - 1.4e-09 37.7 0.1 0.00011 21.6 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KOS19799.1 - 0.00037 19.8 0.1 0.00062 19.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 KOS19799.1 - 0.0011 18.0 0.1 0.0014 17.6 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KOS19799.1 - 0.0025 18.0 0.1 0.0068 16.7 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 KOS19799.1 - 0.0053 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 KOS19799.1 - 0.0078 14.9 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family HSP70 PF00012.15 KOS19800.1 - 1.4e-230 766.3 7.0 1.5e-230 766.2 4.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KOS19800.1 - 4.8e-16 58.2 0.3 5e-15 54.9 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KOS19800.1 - 0.00018 21.1 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 KOS19800.1 - 0.0057 15.5 0.6 0.023 13.5 0.2 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 KOS19800.1 - 0.25 11.2 6.1 1 9.1 0.8 3.7 2 2 0 2 2 2 0 Cell division protein FtsA RNA_pol_Rpb1_1 PF04997.7 KOS19803.1 - 1.3e-101 340.2 0.0 7.9e-101 337.6 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KOS19803.1 - 9.1e-100 333.4 0.0 1.8e-99 332.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KOS19803.1 - 2.6e-70 235.6 0.0 5.8e-70 234.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KOS19803.1 - 1.1e-52 178.5 0.2 2.1e-52 177.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.7 KOS19803.1 - 4.9e-44 149.3 9.8 1.2e-43 148.0 6.6 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.13 KOS19803.1 - 6.7e-43 146.1 0.0 1.4e-42 145.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KOS19803.1 - 2.8e-36 123.5 0.2 6.1e-36 122.4 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Peptidase_M28 PF04389.12 KOS19804.1 - 4.3e-17 62.4 0.1 1.4e-16 60.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.10 KOS19804.1 - 5e-16 58.4 0.0 8.7e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KOS19804.1 - 8.5e-07 28.6 0.3 5.9e-06 25.9 0.2 2.3 1 1 0 1 1 1 1 PA domain Nicastrin PF05450.10 KOS19804.1 - 0.0012 18.1 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 Nicastrin MFS_1 PF07690.11 KOS19805.1 - 8.3e-35 120.1 31.9 7.7e-28 97.2 5.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KOS19805.1 - 2.6e-05 22.6 0.9 5.5e-05 21.5 0.6 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Caps_synth PF05704.7 KOS19806.1 - 7.2e-12 45.0 0.0 1.5e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 KOS19806.1 - 5.5e-06 26.7 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif RNA_pol_Rpb1_5 PF04998.12 KOS19807.1 - 1.2e-71 241.1 0.2 2.4e-71 240.2 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KOS19807.1 - 3.6e-64 215.7 0.7 7.8e-64 214.6 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KOS19807.1 - 3.5e-23 82.0 0.0 1.2e-22 80.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KOS19807.1 - 8.4e-19 68.0 0.9 2.2e-17 63.3 0.1 3.1 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 Nop14 PF04147.7 KOS19807.1 - 0.0021 16.1 8.1 0.0035 15.3 5.6 1.2 1 0 0 1 1 1 1 Nop14-like family WD40 PF00400.27 KOS19808.1 - 2e-05 24.2 5.6 0.0025 17.6 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KOS19808.1 - 0.047 13.1 0.1 2.7 7.5 0.0 3.1 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.6 KOS19808.1 - 0.1 11.8 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split DSPc PF00782.15 KOS19809.1 - 2.2e-28 98.4 0.0 1.2e-21 76.6 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KOS19809.1 - 3.1e-05 23.4 0.0 0.00061 19.2 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KOS19809.1 - 0.023 14.1 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 KOS19809.1 - 0.065 13.2 0.1 0.3 11.1 0.1 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate BPS PF08947.5 KOS19809.1 - 0.38 10.4 3.2 17 5.1 0.8 2.6 2 0 0 2 2 2 0 BPS (Between PH and SH2) DUF1227 PF06777.6 KOS19810.1 - 8.8e-57 190.9 0.4 2.3e-56 189.5 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KOS19810.1 - 5.3e-52 175.7 0.4 9.1e-52 174.9 0.3 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 KOS19810.1 - 1.9e-44 151.5 0.0 4.8e-44 150.2 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 KOS19810.1 - 2.2e-05 23.4 0.0 9.5e-05 21.3 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KOS19810.1 - 0.0011 18.5 0.0 0.22 11.0 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KOS19810.1 - 0.02 15.0 0.1 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 KOS19810.1 - 0.027 14.2 0.2 0.16 11.7 0.1 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 KOS19810.1 - 0.059 12.9 0.5 0.26 10.8 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KOS19810.1 - 0.15 11.7 0.0 0.48 10.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DUF1446 PF07287.6 KOS19811.1 - 1.7e-108 362.3 0.2 2.6e-108 361.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Asp_protease_2 PF13650.1 KOS19812.1 - 2.6e-15 56.6 0.0 4.4e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 KOS19812.1 - 1.6e-11 43.8 0.1 2.4e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 KOS19812.1 - 1.4e-08 34.3 0.0 0.0011 18.5 0.0 2.4 2 1 0 2 2 2 2 Aspartyl protease RVP PF00077.15 KOS19812.1 - 0.0002 21.2 0.0 0.0031 17.4 0.0 2.6 3 0 0 3 3 3 1 Retroviral aspartyl protease DUF1758 PF05585.7 KOS19812.1 - 0.006 16.1 0.0 0.14 11.7 0.0 2.7 3 0 0 3 3 3 1 Putative peptidase (DUF1758) SH3_4 PF06347.8 KOS19812.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Chromo PF00385.19 KOS19814.1 - 1.6e-09 37.3 2.1 4.7e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain CENP-T PF15511.1 KOS19814.1 - 0.21 10.7 16.2 1.7 7.8 11.3 2.0 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Sigma70_ner PF04546.8 KOS19814.1 - 9.3 5.8 10.7 2.2 7.8 3.9 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Ank_2 PF12796.2 KOS19815.1 - 9.8e-44 147.6 16.2 5.6e-16 58.6 0.4 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KOS19815.1 - 3.6e-25 86.4 0.6 4e-08 32.6 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KOS19815.1 - 2.9e-18 65.8 1.9 2e-08 34.4 0.1 4.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS19815.1 - 4.4e-16 57.3 0.2 4.2e-05 23.3 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KOS19815.1 - 4.9e-16 58.3 7.5 1.3e-11 44.3 0.6 3.6 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Peptidase_M20 PF01546.23 KOS19816.1 - 4.2e-06 26.3 3.9 7.2e-06 25.6 2.7 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KOS19816.1 - 0.018 14.7 0.0 0.061 13.0 0.0 1.8 1 1 0 1 1 1 0 Peptidase dimerisation domain zf-H2C2_2 PF13465.1 KOS19817.1 - 1.9e-08 34.1 9.3 0.0016 18.6 0.4 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KOS19817.1 - 4.5e-05 23.5 3.3 4.5e-05 23.5 2.3 3.0 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-Di19 PF05605.7 KOS19817.1 - 4.6e-05 23.4 3.8 0.00014 21.8 0.1 2.4 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KOS19817.1 - 0.0018 17.8 1.0 0.0018 17.8 0.7 2.1 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 KOS19817.1 - 0.0029 17.8 2.3 0.0029 17.8 1.6 3.2 3 1 0 3 3 3 1 C2H2-type zinc finger zf-ISL3 PF14690.1 KOS19817.1 - 0.0092 15.9 0.9 0.0092 15.9 0.6 2.4 2 1 1 3 3 3 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 IBR PF01485.16 KOS19817.1 - 0.016 15.0 0.9 0.039 13.8 0.6 1.6 1 1 0 1 1 1 0 IBR domain ADK_lid PF05191.9 KOS19817.1 - 0.045 13.4 0.6 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid ARS2 PF04959.8 KOS19817.1 - 0.065 13.4 1.3 0.12 12.5 0.3 1.7 1 1 0 2 2 2 0 Arsenite-resistance protein 2 Rad50_zn_hook PF04423.9 KOS19817.1 - 0.074 12.5 0.2 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zinc_ribbon_2 PF13240.1 KOS19817.1 - 0.14 11.7 0.3 0.14 11.7 0.2 1.9 2 0 0 2 2 2 0 zinc-ribbon domain DUF1644 PF07800.7 KOS19817.1 - 0.22 11.3 2.3 1 9.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-IS66 PF13005.2 KOS19817.1 - 2.5 8.1 7.0 26 4.8 3.0 3.1 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Zn-ribbon_8 PF09723.5 KOS19817.1 - 3.3 7.7 5.5 2.8 7.9 0.5 2.4 2 1 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 KOS19817.1 - 4.5 7.0 6.6 2.4 8.0 0.7 2.6 2 1 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 KOS19817.1 - 5.9 7.1 6.4 1.6 8.9 0.3 2.9 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding polyprenyl_synt PF00348.12 KOS19818.1 - 3.4e-36 124.4 0.0 4.8e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 KOS19818.1 - 0.014 14.5 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain MFS_1 PF07690.11 KOS19819.1 - 1.7e-16 59.8 19.2 2.6e-16 59.3 13.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DPBB_1 PF03330.13 KOS19820.1 - 1.6e-05 24.8 0.6 4.4e-05 23.3 0.4 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KOS19820.1 - 0.0011 18.5 1.6 0.0016 18.1 1.1 1.5 1 1 0 1 1 1 1 Barwin family ParA PF10609.4 KOS19821.1 - 8.4e-32 108.8 0.5 1.7e-31 107.9 0.3 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like DUF4537 PF15057.1 KOS19822.1 - 0.0017 18.1 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) GOLGA2L5 PF15070.1 KOS19822.1 - 0.0098 14.4 6.9 0.015 13.8 4.8 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Agenet PF05641.7 KOS19822.1 - 0.015 15.4 0.1 0.075 13.1 0.0 2.2 2 0 0 2 2 2 0 Agenet domain PixA PF12306.3 KOS19822.1 - 0.02 14.7 3.0 1.2 8.9 0.8 2.4 2 0 0 2 2 2 0 Inclusion body protein Rad9_Rad53_bind PF08605.5 KOS19822.1 - 0.04 13.6 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding RP-C_C PF11800.3 KOS19822.1 - 0.047 13.3 5.6 0.099 12.3 3.8 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2868 PF11067.3 KOS19822.1 - 1.1 8.3 5.4 1.7 7.6 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Ndc1_Nup PF09531.5 KOS19822.1 - 7.9 4.7 10.9 10 4.4 7.6 1.4 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Fungal_trans PF04082.13 KOS19824.1 - 1e-13 50.7 0.1 2e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS19824.1 - 0.0031 17.3 6.4 0.0056 16.5 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gly-zipper_OmpA PF13436.1 KOS19824.1 - 2.7 7.6 9.5 8.2 6.1 6.6 1.8 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Peptidase_C2 PF00648.16 KOS19825.1 - 3.2e-27 95.3 0.0 6.6e-15 54.8 0.0 2.1 2 0 0 2 2 2 2 Calpain family cysteine protease Fungal_trans PF04082.13 KOS19826.1 - 2.9e-07 29.6 2.8 1.6e-06 27.2 0.2 2.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain PhyH PF05721.8 KOS19827.1 - 8.6e-10 39.0 0.0 1.4e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AraC_binding PF02311.14 KOS19827.1 - 0.011 15.4 0.5 0.033 13.8 0.3 1.8 1 0 0 1 1 1 0 AraC-like ligand binding domain Aldedh PF00171.17 KOS19828.1 - 1.5e-141 471.8 0.0 1.9e-141 471.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KOS19828.1 - 0.028 13.1 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Romo1 PF10247.4 KOS19828.1 - 0.11 12.6 2.2 0.27 11.4 1.5 1.6 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Glyco_hydro_92 PF07971.7 KOS19829.1 - 5.9e-164 546.4 0.1 7.3e-164 546.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Ferric_reduct PF01794.14 KOS19830.1 - 2.7e-16 59.8 7.3 2.7e-16 59.8 5.1 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KOS19830.1 - 6.3e-16 58.6 0.0 2.1e-13 50.4 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KOS19830.1 - 5.3e-09 35.9 0.0 0.0024 17.6 0.1 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 KOS19830.1 - 0.00019 21.9 0.0 0.0009 19.7 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain CFEM PF05730.6 KOS19830.1 - 0.15 11.8 5.3 0.27 11.0 3.7 1.3 1 0 0 1 1 1 0 CFEM domain Aldedh PF00171.17 KOS19831.1 - 4.6e-121 404.3 0.0 5.8e-121 404.0 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Robl_LC7 PF03259.12 KOS19832.1 - 8.1e-10 38.1 0.3 2.4e-06 27.0 0.0 2.5 1 1 2 3 3 3 2 Roadblock/LC7 domain DUF1180 PF06679.7 KOS19832.1 - 0.09 12.6 1.9 0.13 12.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4400 PF14348.1 KOS19832.1 - 0.12 11.6 0.3 0.16 11.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Ceramidase_alk PF04734.8 KOS19834.1 - 1.5e-272 905.4 0.0 1.7e-272 905.2 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase MFS_1 PF07690.11 KOS19835.1 - 1.3e-39 135.9 49.7 2.3e-39 135.1 33.8 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KOS19835.1 - 2.4e-14 52.4 29.6 3.8e-14 51.8 20.5 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Usp PF00582.21 KOS19836.1 - 3.8e-22 78.9 3.7 1.8e-13 50.8 0.1 3.0 3 0 0 3 3 3 2 Universal stress protein family Ribosomal_S7 PF00177.16 KOS19837.1 - 1.6e-23 82.9 0.0 2.4e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Piwi PF02171.12 KOS19838.1 - 2.2e-73 246.8 0.0 3.1e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KOS19838.1 - 4.6e-07 29.1 0.1 1.4e-06 27.5 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) Abhydrolase_6 PF12697.2 KOS19841.1 - 1.9e-22 80.2 6.0 1.9e-22 80.2 4.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS19841.1 - 0.00011 21.9 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS19841.1 - 0.0027 17.3 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 KOS19841.1 - 0.15 10.2 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II dCMP_cyt_deam_1 PF00383.17 KOS19843.1 - 1.6e-11 43.7 0.0 2.2e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region OPT PF03169.10 KOS19844.1 - 6.8e-129 431.1 45.8 7.7e-129 430.9 31.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Caps_synth PF05704.7 KOS19845.1 - 3.7e-21 75.5 0.0 6.3e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 KOS19845.1 - 2.9e-07 30.8 0.0 5.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Ribosomal_L50 PF10501.4 KOS19847.1 - 9.2e-12 44.9 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S Pex24p PF06398.6 KOS19848.1 - 5.6e-97 324.7 0.3 8.5e-97 324.1 0.2 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin EIIC-GAT PF03611.9 KOS19848.1 - 0.09 11.5 1.1 0.15 10.7 0.8 1.2 1 0 0 1 1 1 0 PTS system sugar-specific permease component Tir_receptor_C PF07489.6 KOS19849.1 - 0.11 12.2 5.8 0.12 12.0 4.0 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Ribosomal_L13e PF01294.13 KOS19850.1 - 4.7e-60 202.1 2.3 6.6e-60 201.6 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e COX14 PF14880.1 KOS19851.1 - 3.6e-19 68.1 0.4 3.6e-19 68.1 0.3 1.7 2 0 0 2 2 2 1 Cytochrome oxidase c assembly PRP4 PF08799.6 KOS19851.1 - 0.026 13.8 0.1 0.065 12.5 0.1 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Cas_Cas02710 PF09670.5 KOS19851.1 - 0.051 12.2 0.1 0.062 11.9 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) DAHP_synth_1 PF00793.15 KOS19853.1 - 3e-97 324.5 0.0 3.6e-97 324.2 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family OMPdecase PF00215.19 KOS19853.1 - 0.066 12.5 0.1 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family HrpB4 PF09502.5 KOS19854.1 - 0.01 15.0 0.1 0.011 14.9 0.0 1.0 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) p450 PF00067.17 KOS19855.1 - 1.5e-55 188.5 0.0 3.8e-55 187.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 KOS19856.1 - 8.7e-14 51.3 0.0 1.2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain ERG2_Sigma1R PF04622.7 KOS19856.1 - 0.14 11.4 0.2 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein IDO PF01231.13 KOS19857.1 - 2.6e-170 566.4 0.0 3e-170 566.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 KOS19857.1 - 0.13 10.7 0.0 0.42 9.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) RNA_pol_Rpb2_6 PF00562.23 KOS19858.1 - 2.9e-125 418.0 0.6 1.1e-124 416.0 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KOS19858.1 - 1.1e-52 177.9 0.0 2e-52 177.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KOS19858.1 - 5.4e-46 156.4 0.0 1.2e-45 155.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KOS19858.1 - 1.2e-30 105.5 0.0 2.8e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KOS19858.1 - 5e-24 84.0 0.4 1.2e-23 82.7 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 KOS19858.1 - 5.7e-23 80.4 0.1 1.4e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KOS19858.1 - 3e-18 65.3 0.1 8.3e-18 63.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 DUF3658 PF12395.3 KOS19859.1 - 0.011 15.2 0.3 0.014 14.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function V-ATPase_G PF03179.10 KOS19860.1 - 2.4e-27 95.2 12.4 2.8e-27 95.0 8.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Striatin PF08232.7 KOS19860.1 - 0.02 15.1 4.2 0.025 14.8 2.9 1.1 1 0 0 1 1 1 0 Striatin family YusW PF14039.1 KOS19860.1 - 0.023 14.9 3.5 0.034 14.4 2.3 1.3 1 1 0 1 1 1 0 YusW-like protein MMR_HSR1_C PF08438.5 KOS19860.1 - 0.037 14.2 2.0 0.15 12.2 0.5 1.9 1 1 0 2 2 2 0 GTPase of unknown function C-terminal RRF PF01765.14 KOS19860.1 - 0.18 11.2 7.8 0.23 10.9 5.4 1.1 1 0 0 1 1 1 0 Ribosome recycling factor AAA_13 PF13166.1 KOS19860.1 - 0.56 8.5 7.5 0.63 8.4 5.2 1.0 1 0 0 1 1 1 0 AAA domain Gcd10p PF04189.8 KOS19860.1 - 0.57 9.2 4.7 0.66 9.0 3.3 1.0 1 0 0 1 1 1 0 Gcd10p family Carboxyl_trans PF01039.17 KOS19860.1 - 1 7.6 4.8 1.2 7.4 3.3 1.0 1 0 0 1 1 1 0 Carboxyl transferase domain EspA PF03433.8 KOS19860.1 - 1.1 8.7 5.1 1.7 8.0 3.5 1.5 1 1 0 1 1 1 0 EspA-like secreted protein OmpH PF03938.9 KOS19860.1 - 2.8 7.8 11.3 3.5 7.5 7.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CTNNBL PF08216.6 KOS19861.1 - 1.1e-30 105.3 0.1 2.5e-30 104.2 0.1 1.6 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Cytochrom_D1 PF02239.11 KOS19862.1 - 0.16 10.1 0.0 0.27 9.4 0.0 1.3 1 1 0 1 1 1 0 Cytochrome D1 heme domain RNase_T PF00929.19 KOS19863.1 - 1e-12 48.6 0.1 1.2e-12 48.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease SHNi-TPR PF10516.4 KOS19863.1 - 0.031 13.5 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 SHNi-TPR CK_II_beta PF01214.13 KOS19864.1 - 5.9e-76 254.0 0.0 1.1e-75 253.1 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 KOS19864.1 - 0.019 15.5 10.0 0.022 15.3 2.4 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.1 KOS19864.1 - 3.9 7.8 10.8 6.2 7.1 1.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 KOS19864.1 - 9.3 6.5 13.8 7.6 6.8 4.9 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cupin_8 PF13621.1 KOS19865.1 - 1.7e-22 80.1 0.0 1.9e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KOS19865.1 - 0.00024 21.3 0.0 0.00048 20.3 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KOS19865.1 - 0.0027 17.1 0.0 0.0074 15.7 0.0 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.7 KOS19865.1 - 0.011 15.0 0.1 0.024 13.8 0.0 1.6 2 0 0 2 2 2 0 Cupin superfamily protein AraC_binding PF02311.14 KOS19865.1 - 0.11 12.1 0.1 0.86 9.2 0.0 2.1 2 0 0 2 2 2 0 AraC-like ligand binding domain Pro-kuma_activ PF09286.6 KOS19866.1 - 5.7e-43 146.3 0.0 1e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KOS19866.1 - 8.9e-07 28.3 0.6 2.7e-06 26.7 0.4 1.6 1 1 0 1 1 1 1 Subtilase family Copper-fist PF00649.13 KOS19867.1 - 3.9e-22 77.1 1.4 3.9e-22 77.1 0.9 4.6 2 1 3 5 5 5 1 Copper fist DNA binding domain Fungal_trans PF04082.13 KOS19868.1 - 7.8e-09 34.7 0.1 2.7e-08 33.0 0.1 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain bZIP_1 PF00170.16 KOS19868.1 - 0.08 12.9 2.7 0.15 12.0 1.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor Methyltransf_25 PF13649.1 KOS19869.1 - 7.1e-11 42.3 0.1 1.9e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS19869.1 - 1.8e-06 27.5 0.0 2.2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS19869.1 - 0.00013 22.4 0.0 0.00022 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS19869.1 - 0.00015 22.1 0.0 0.00033 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS19869.1 - 0.0019 18.2 0.2 0.0031 17.5 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS19869.1 - 0.0033 17.1 0.0 0.0049 16.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS19869.1 - 0.011 16.3 0.1 0.017 15.6 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.8 KOS19869.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Cellulase PF00150.13 KOS19870.1 - 9.3e-14 51.2 0.2 9.3e-14 51.2 0.2 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Rtf2 PF04641.7 KOS19873.1 - 1.9e-51 174.7 6.8 4.2e-51 173.6 4.7 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 KOS19873.1 - 0.00022 20.8 0.2 0.00057 19.5 0.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KOS19873.1 - 0.0016 18.1 0.1 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KOS19873.1 - 0.018 14.8 0.2 0.051 13.4 0.1 1.7 1 1 1 2 2 2 0 Ring finger domain UPF0547 PF10571.4 KOS19873.1 - 0.021 14.5 2.3 1.8 8.3 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C3HC4_2 PF13923.1 KOS19873.1 - 0.045 13.7 0.4 0.087 12.8 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS19873.1 - 0.057 13.1 0.1 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.5 KOS19873.1 - 0.09 12.7 0.8 0.23 11.4 0.6 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Vfa1 PF08432.5 KOS19873.1 - 0.092 12.7 13.9 0.13 12.2 9.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 U79_P34 PF03064.11 KOS19873.1 - 0.72 9.3 15.0 0.96 8.9 10.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Atrophin-1 PF03154.10 KOS19873.1 - 1.9 6.5 10.6 2.8 5.9 7.3 1.2 1 0 0 1 1 1 0 Atrophin-1 family FYDLN_acid PF09538.5 KOS19873.1 - 2.2 8.8 14.9 1.6 9.3 8.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) NPR3 PF03666.8 KOS19873.1 - 4.8 5.6 8.9 6.3 5.2 6.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM176 PF14851.1 KOS19873.1 - 5.5 6.6 8.0 8.8 5.9 5.6 1.3 1 0 0 1 1 1 0 FAM176 family Yip1 PF04893.12 KOS19874.1 - 3.9e-08 32.9 13.7 4.5e-05 23.0 6.3 2.3 2 0 0 2 2 2 2 Yip1 domain RCC1 PF00415.13 KOS19875.1 - 2.7e-65 216.3 5.3 1.9e-12 47.2 0.1 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KOS19875.1 - 1.8e-37 126.1 29.6 1.3e-10 40.6 0.8 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 KOS19875.1 - 0.027 13.9 0.1 8.3 5.9 0.0 2.7 2 0 0 2 2 2 0 Putative carbohydrate binding domain Methyltransf_23 PF13489.1 KOS19876.1 - 6.7e-19 68.1 0.1 9.5e-19 67.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS19876.1 - 4.1e-07 30.4 0.0 2.8e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS19876.1 - 5.2e-07 30.2 0.0 3.8e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS19876.1 - 1.2e-06 28.2 0.0 8.2e-06 25.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS19876.1 - 2.3e-05 24.7 0.0 5.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS19876.1 - 2.6e-05 24.5 0.0 0.00021 21.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS19876.1 - 8.3e-05 22.6 0.0 0.00021 21.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KOS19876.1 - 0.021 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 KOS19876.1 - 0.023 14.0 0.0 0.13 11.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KOS19876.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) D-ser_dehydrat PF14031.1 KOS19878.1 - 2e-20 72.7 0.1 3.9e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KOS19878.1 - 6.7e-12 45.4 3.3 6.3e-08 32.4 0.6 2.2 2 0 0 2 2 2 2 Alanine racemase, N-terminal domain TrkA_C PF02080.16 KOS19878.1 - 0.021 14.4 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-C domain PAP_assoc PF03828.14 KOS19879.1 - 1.3e-11 44.2 0.1 2.5e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KOS19879.1 - 6.2e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_phi PF04931.8 KOS19879.1 - 7.1 4.2 7.8 11 3.6 5.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Fungal_trans PF04082.13 KOS19880.1 - 1.3e-14 53.7 1.7 1.2e-12 47.2 0.0 2.7 2 1 1 3 3 3 2 Fungal specific transcription factor domain MFS_1 PF07690.11 KOS19881.1 - 6.9e-31 107.2 28.7 1.3e-30 106.3 18.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Pertus-S4-tox PF09275.5 KOS19881.1 - 0.097 12.7 0.1 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Pertussis toxin S4 subunit 4HBT PF03061.17 KOS19882.1 - 1.5e-07 31.3 0.7 5.5e-07 29.6 0.1 1.9 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.1 KOS19882.1 - 0.00034 21.0 0.0 0.00044 20.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Glyoxalase_5 PF14696.1 KOS19882.1 - 0.06 13.2 0.0 0.076 12.9 0.0 1.1 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF3751 PF12571.3 KOS19882.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Phage tail-collar fibre protein LAP2alpha PF11560.3 KOS19883.1 - 0.15 11.2 0.1 0.28 10.3 0.0 1.5 2 0 0 2 2 2 0 Lamina-associated polypeptide 2 alpha Glyco_hydro_71 PF03659.9 KOS19884.1 - 5.9e-132 439.7 7.0 7e-132 439.5 4.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 KOS19884.1 - 0.086 12.5 0.2 0.29 10.8 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) p450 PF00067.17 KOS19885.1 - 1.2e-33 116.3 0.0 1.6e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.3 KOS19887.1 - 1.2e-72 245.1 0.0 1.4e-72 244.9 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.17 KOS19888.1 - 4.6e-36 124.3 0.0 5.6e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glycophorin_A PF01102.13 KOS19888.1 - 0.072 12.8 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Glycophorin A DUF3146 PF11344.3 KOS19888.1 - 0.14 11.6 0.0 0.39 10.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3146) DUF1680 PF07944.7 KOS19889.1 - 0.014 13.7 0.0 0.017 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) GlcNAc_2-epim PF07221.6 KOS19889.1 - 0.062 12.3 0.0 7.6 5.4 0.0 2.2 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Pyr_redox_2 PF07992.9 KOS19890.1 - 1.3e-25 90.4 0.0 3.2e-25 89.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KOS19890.1 - 3.2e-15 55.4 0.0 8.3e-15 54.1 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 KOS19890.1 - 1.6e-13 50.8 3.4 2.3e-11 43.9 0.5 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KOS19890.1 - 1.8e-09 37.9 0.1 0.00017 21.7 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 KOS19890.1 - 2.4e-05 24.5 0.0 7.8e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.1 KOS19890.1 - 3.9e-05 23.3 0.0 0.00015 21.4 0.0 2.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.1 KOS19890.1 - 9.3e-05 21.4 0.1 0.055 12.3 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KOS19890.1 - 0.00019 21.2 4.5 0.18 11.5 0.0 3.2 2 1 1 3 3 3 2 FAD-NAD(P)-binding PS_pyruv_trans PF04230.8 KOS19890.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase DivIVA PF05103.8 KOS19891.1 - 1.7 8.7 23.1 1.6 8.7 0.1 3.8 2 1 1 3 3 3 0 DivIVA protein Fib_alpha PF08702.5 KOS19891.1 - 5.4 7.1 10.8 1.1 9.3 2.2 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Glyco_hydro_18 PF00704.23 KOS19894.1 - 1e-49 169.8 0.7 1.2e-49 169.6 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 p450 PF00067.17 KOS19895.1 - 2e-20 72.8 0.2 1.6e-15 56.6 0.1 2.0 1 1 1 2 2 2 2 Cytochrome P450 Pyr_redox_2 PF07992.9 KOS19896.1 - 6.3e-05 22.9 0.0 0.00018 21.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS19896.1 - 0.00078 19.2 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KOS19896.1 - 0.0028 17.7 0.1 0.025 14.6 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KOS19896.1 - 0.012 14.5 0.0 0.03 13.2 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase OTT_1508_deam PF14441.1 KOS19897.1 - 6e-10 39.0 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Fe_dep_repr_C PF02742.10 KOS19897.1 - 0.013 15.1 1.0 0.027 14.1 0.2 1.9 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Mac PF12464.3 KOS19898.1 - 1.4e-19 69.7 0.1 2.1e-19 69.2 0.1 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 KOS19898.1 - 3.2e-16 58.0 8.9 5.8e-13 47.7 3.1 3.5 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KOS19898.1 - 1.1e-13 50.4 13.1 1.9e-13 49.6 2.2 3.7 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Subtilosin_A PF11420.3 KOS19898.1 - 0.02 14.9 0.3 0.057 13.4 0.2 1.8 1 0 0 1 1 1 0 Bacteriocin subtilosin A Ank_2 PF12796.2 KOS19899.1 - 5.2e-27 94.0 0.1 1.2e-13 51.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KOS19899.1 - 3.4e-25 86.5 0.6 1e-07 31.4 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat HET PF06985.6 KOS19899.1 - 8.6e-21 74.5 7.7 1e-17 64.6 0.0 3.4 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Ank_5 PF13857.1 KOS19899.1 - 8.6e-18 63.9 1.2 4.1e-06 26.8 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS19899.1 - 4.9e-17 60.3 0.0 0.0028 17.7 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KOS19899.1 - 5.2e-17 61.8 4.1 1e-08 35.4 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DivIC PF04977.10 KOS19899.1 - 1.5 8.3 13.3 1.4 8.4 0.4 3.4 3 0 0 3 3 3 0 Septum formation initiator CBM_14 PF01607.19 KOS19900.1 - 0.00088 19.1 15.4 0.075 12.9 0.9 4.1 1 1 2 3 3 3 3 Chitin binding Peritrophin-A domain TIL PF01826.12 KOS19900.1 - 0.047 13.7 19.6 0.1 12.7 5.9 3.3 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain ADH_N PF08240.7 KOS19901.1 - 1e-25 89.6 1.4 2.2e-25 88.5 1.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 KOS19901.1 - 4.6e-07 29.3 0.1 4.6e-07 29.3 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 KOS19901.1 - 0.0014 18.2 0.1 0.1 12.1 0.0 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 KOS19901.1 - 0.088 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rft-1 PF04506.8 KOS19902.1 - 3.2e-92 309.6 9.7 3.5e-92 309.5 6.7 1.0 1 0 0 1 1 1 1 Rft protein SurE PF01975.12 KOS19903.1 - 4.2e-43 146.9 0.0 6.4e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE PQQ PF01011.16 KOS19904.1 - 0.016 14.7 0.0 0.049 13.1 0.0 1.8 1 0 0 1 1 1 0 PQQ enzyme repeat SBP56 PF05694.6 KOS19904.1 - 0.041 12.3 0.0 0.091 11.2 0.0 1.5 2 0 0 2 2 2 0 56kDa selenium binding protein (SBP56) Abhydrolase_1 PF00561.15 KOS19905.1 - 2.7e-09 36.9 0.0 5.3e-09 35.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KOS19905.1 - 2.3e-06 27.6 5.8 4.7e-06 26.6 4.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Tfb2 PF03849.9 KOS19907.1 - 3e-136 453.8 0.0 3.8e-136 453.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KOS19907.1 - 2.6e-05 23.9 0.1 6.7e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 KOS19907.1 - 0.067 12.6 0.4 2 7.9 0.0 2.8 2 0 0 2 2 2 0 Anti-repressor SinI DUF829 PF05705.9 KOS19908.1 - 6.5e-20 71.8 0.0 8e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Patatin PF01734.17 KOS19913.1 - 9.3e-26 91.0 0.0 1.7e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase GFO_IDH_MocA PF01408.17 KOS19914.1 - 2.8e-17 63.3 0.1 7.1e-17 62.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KOS19914.1 - 0.0027 17.4 0.1 0.0095 15.7 0.1 2.0 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain End3 PF12761.2 KOS19915.1 - 0.014 15.0 4.2 0.025 14.2 2.9 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Kinetocho_Slk19 PF12709.2 KOS19915.1 - 0.19 11.8 5.4 0.16 12.0 1.6 2.6 3 1 0 3 3 3 0 Central kinetochore-associated DUF3166 PF11365.3 KOS19915.1 - 0.76 10.2 4.3 0.27 11.7 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3166) Mto2_bdg PF12808.2 KOS19915.1 - 1.3 9.1 15.5 0.89 9.7 0.2 4.5 4 0 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Cortex-I_coil PF09304.5 KOS19915.1 - 1.6 8.8 9.7 0.27 11.2 1.6 2.6 1 1 0 2 2 2 0 Cortexillin I, coiled coil CENP-Q PF13094.1 KOS19915.1 - 5.1 7.1 12.0 2.8 7.9 1.6 3.3 2 1 2 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-UBR PF02207.15 KOS19916.1 - 4.4e-16 58.3 4.3 4.4e-16 58.3 3.0 3.4 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) zf-C2H2_4 PF13894.1 KOS19917.1 - 1.7e-08 34.2 15.0 0.12 12.8 1.0 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger Peptidase_C14 PF00656.17 KOS19917.1 - 0.0058 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Caspase domain zf-C2H2 PF00096.21 KOS19917.1 - 2.4 8.6 19.9 0.55 10.6 1.0 4.3 4 1 0 4 4 4 0 Zinc finger, C2H2 type Glyco_hydro_31 PF01055.21 KOS19918.1 - 4.3e-175 582.7 1.4 5.6e-175 582.3 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KOS19918.1 - 8.1e-11 41.6 0.4 8.1e-11 41.6 0.3 3.1 3 0 0 3 3 3 1 Galactose mutarotase-like Malate_synthase PF01274.17 KOS19919.1 - 1.6e-222 739.1 0.0 2e-222 738.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 KOS19919.1 - 0.0029 16.5 0.0 0.0063 15.4 0.0 1.5 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF3329 PF11808.3 KOS19920.1 - 0.23 11.5 1.0 0.33 11.0 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) RRM_1 PF00076.17 KOS19921.1 - 2.1e-08 33.6 0.1 4.8e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS19921.1 - 4.5e-07 29.7 0.7 1.1e-06 28.4 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KOS19921.1 - 0.00043 19.9 0.0 0.0017 18.0 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif ADIP PF11559.3 KOS19922.1 - 0.00052 19.9 2.3 0.00064 19.6 1.6 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Tol_Tol_Ttg2 PF05494.7 KOS19922.1 - 0.059 12.9 0.5 0.092 12.2 0.3 1.3 1 0 0 1 1 1 0 Toluene tolerance, Ttg2 4HB_MCP_1 PF12729.2 KOS19922.1 - 0.17 11.2 1.2 0.23 10.8 0.8 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Striatin PF08232.7 KOS19923.1 - 0.01 16.1 3.0 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 Striatin family BBP1_C PF15272.1 KOS19923.1 - 0.12 11.8 0.6 0.34 10.4 0.1 1.8 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Phage_lysis PF03245.8 KOS19923.1 - 0.19 11.7 0.2 0.19 11.7 0.1 2.4 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein SPX PF03105.14 KOS19923.1 - 0.43 10.3 2.5 4.6 6.9 2.3 2.0 1 1 1 2 2 2 0 SPX domain FAA_hydrolase PF01557.13 KOS19924.1 - 2.9e-48 164.1 0.0 4.6e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KOS19924.1 - 7.4e-25 87.0 0.0 1.4e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal TRAUB PF08164.7 KOS19925.1 - 1.5e-31 108.2 0.9 3.8e-31 107.0 0.3 2.1 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KOS19925.1 - 1.2e-26 93.4 0.2 1.2e-26 93.4 0.1 3.5 4 1 1 5 5 5 1 Apoptosis antagonizing transcription factor eIF-3c_N PF05470.7 KOS19925.1 - 0.016 13.2 0.1 0.016 13.2 0.0 3.2 1 1 2 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Raptor_N PF14538.1 KOS19926.1 - 2.7e-64 215.6 0.0 5.3e-64 214.7 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KOS19926.1 - 9.5e-08 31.6 5.4 0.44 10.5 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 KOS19926.1 - 5.6e-06 26.1 0.2 0.022 14.5 0.1 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.4 KOS19926.1 - 0.0008 19.1 0.2 0.0016 18.1 0.1 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.1 KOS19926.1 - 0.039 14.2 0.1 1 9.7 0.0 3.3 3 1 0 3 3 3 0 HEAT repeats IKI3 PF04762.7 KOS19926.1 - 0.043 11.6 0.0 0.063 11.0 0.0 1.2 1 0 0 1 1 1 0 IKI3 family DUF1900 PF08954.6 KOS19926.1 - 0.13 11.8 0.0 11 5.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1900) HEAT PF02985.17 KOS19926.1 - 0.28 11.3 4.5 0.96 9.7 0.1 4.2 5 0 0 5 5 5 0 HEAT repeat Kelch_4 PF13418.1 KOS19927.1 - 5.8e-35 118.8 13.1 1.4e-07 31.1 0.3 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KOS19927.1 - 5.6e-32 109.1 5.9 3.1e-09 36.5 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KOS19927.1 - 1.9e-30 104.2 16.4 1.6e-08 34.4 0.1 6.5 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.20 KOS19927.1 - 6.7e-26 89.5 4.7 6.4e-10 38.4 0.2 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 KOS19927.1 - 1.1e-25 88.7 8.8 2.5e-11 43.2 0.4 6.4 5 1 1 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KOS19927.1 - 1.1e-20 72.4 6.5 1.8e-07 30.6 0.2 6.4 6 0 0 6 6 6 5 Kelch motif RAG2 PF03089.9 KOS19927.1 - 0.045 12.4 0.1 1 8.0 0.0 3.0 4 0 0 4 4 4 0 Recombination activating protein 2 DUF605 PF04652.11 KOS19928.1 - 0.32 10.3 4.7 0.4 10.0 3.3 1.1 1 0 0 1 1 1 0 Vta1 like VHS PF00790.14 KOS19929.1 - 1.1e-40 138.5 1.1 2.1e-39 134.3 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KOS19929.1 - 3.6e-17 62.0 1.9 6e-17 61.3 1.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 KOS19929.1 - 7.8e-05 21.9 15.6 0.003 16.9 0.6 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.11 KOS19929.1 - 0.021 14.6 0.3 0.045 13.6 0.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-DHHC PF01529.15 KOS19929.1 - 0.022 14.1 0.4 0.022 14.1 0.3 1.8 2 1 0 2 2 2 0 DHHC palmitoyltransferase C1_1 PF00130.17 KOS19929.1 - 0.06 13.0 3.0 0.11 12.1 2.1 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GAT PF03127.9 KOS19929.1 - 0.087 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 GAT domain Ribosomal_S30AE PF02482.14 KOS19929.1 - 0.2 12.0 2.6 0.67 10.4 1.8 1.9 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein UCH PF00443.24 KOS19930.1 - 2.4e-40 138.3 0.0 3.7e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS19930.1 - 4.6e-15 55.8 0.0 8.1e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 KOS19930.1 - 1e-06 29.0 0.0 2.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain AMP-binding PF00501.23 KOS19931.1 - 4.4e-78 262.5 0.0 7.1e-78 261.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NTP_transferase PF00483.18 KOS19932.1 - 2e-46 158.3 0.0 4.7e-46 157.0 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 KOS19932.1 - 4e-17 60.8 10.9 2.1e-10 39.6 0.5 4.1 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KOS19932.1 - 1e-09 38.6 0.0 1.5e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KOS19932.1 - 1.2e-08 34.3 5.2 3.6e-07 29.6 0.8 3.3 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 KOS19932.1 - 0.029 14.0 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 Cytidylyltransferase Prenyltrans PF00432.16 KOS19933.1 - 9.8e-33 111.3 27.2 4.8e-09 35.6 0.6 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KOS19933.1 - 4.6e-20 72.0 0.3 1.3e-14 54.5 0.1 4.1 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KOS19933.1 - 0.00064 19.7 0.0 0.0035 17.3 0.0 2.0 2 0 0 2 2 2 1 Prenyltransferase-like BRAP2 PF07576.7 KOS19935.1 - 3e-20 71.8 0.0 5.6e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 KOS19935.1 - 4.8e-18 65.0 9.4 1.3e-17 63.6 6.5 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 KOS19935.1 - 2.2e-10 40.1 9.7 2.2e-10 40.1 6.7 2.3 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.1 KOS19935.1 - 3.4e-06 26.6 7.6 3.4e-06 26.6 5.2 2.5 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KOS19935.1 - 9.9e-05 21.9 8.7 9.9e-05 21.9 6.0 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS19935.1 - 0.0018 18.2 9.7 0.0018 18.2 6.7 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KOS19935.1 - 0.0042 16.7 6.6 0.019 14.6 3.7 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 KOS19935.1 - 0.009 15.7 4.1 0.025 14.3 2.8 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KOS19935.1 - 0.011 15.8 5.5 0.011 15.8 3.8 2.0 2 0 0 2 2 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KOS19935.1 - 0.062 13.1 5.9 0.21 11.4 4.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF972 PF06156.8 KOS19935.1 - 0.33 11.2 3.3 0.16 12.3 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Exonuc_VII_L PF02601.10 KOS19935.1 - 5.4 6.1 8.0 11 5.0 5.5 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit STE2 PF02116.10 KOS19936.1 - 1.3e-39 135.9 9.9 1.8e-39 135.5 6.9 1.2 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR UEV PF05743.8 KOS19937.1 - 2.7e-37 127.1 0.1 4.4e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 KOS19937.1 - 1.2e-21 76.1 0.0 2.2e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 KOS19937.1 - 0.00077 18.8 0.1 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TFIIA PF03153.8 KOS19937.1 - 6.8 6.4 13.4 9.8 5.9 9.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit E1-E2_ATPase PF00122.15 KOS19938.1 - 1.9e-13 50.0 0.4 5.3e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KOS19938.1 - 2.3e-12 46.7 0.0 6.5e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KOS19938.1 - 3.1e-11 44.1 0.1 1.7e-08 35.1 0.1 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KOS19938.1 - 3.1e-11 43.8 0.0 8.4e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KOS19938.1 - 0.015 14.9 0.4 0.027 14.0 0.3 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PQ-loop PF04193.9 KOS19939.1 - 9.6e-37 124.3 17.5 7.7e-22 76.6 1.5 3.3 4 0 0 4 4 4 2 PQ loop repeat NfeD PF01957.13 KOS19939.1 - 0.11 12.5 4.3 2.9 8.0 0.0 2.9 4 0 0 4 4 4 0 NfeD-like C-terminal, partner-binding DUF3169 PF11368.3 KOS19939.1 - 3.5 6.7 6.6 1.5 7.9 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) S1-P1_nuclease PF02265.11 KOS19940.1 - 1.8e-67 227.5 4.7 2.1e-67 227.4 3.2 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease HAD_2 PF13419.1 KOS19940.1 - 0.035 14.3 0.3 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PSI_PSAK PF01241.13 KOS19940.1 - 0.15 12.0 0.5 0.28 11.2 0.3 1.4 1 0 0 1 1 1 0 Photosystem I psaG / psaK zf-RING_2 PF13639.1 KOS19941.1 - 1.4e-13 50.3 5.4 2.2e-13 49.7 3.7 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KOS19941.1 - 9.9e-12 44.4 0.3 2.9e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 PA domain zf-rbx1 PF12678.2 KOS19941.1 - 4.1e-09 36.4 1.7 7.8e-09 35.5 1.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KOS19941.1 - 1.2e-08 34.7 5.4 1.9e-08 34.1 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS19941.1 - 1.3e-08 34.3 3.2 2e-08 33.7 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS19941.1 - 1.9e-07 30.6 3.0 2.8e-07 30.1 2.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS19941.1 - 4e-07 29.6 2.2 6e-07 29.0 1.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KOS19941.1 - 0.0013 18.5 0.8 0.0024 17.6 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KOS19941.1 - 0.017 14.8 2.6 0.041 13.5 1.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KOS19941.1 - 0.13 12.1 2.9 0.47 10.3 2.2 1.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KOS19941.1 - 0.15 12.0 2.7 0.46 10.4 1.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Baculo_RING PF05883.6 KOS19941.1 - 0.16 11.7 0.1 0.28 11.0 0.1 1.2 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain RINGv PF12906.2 KOS19941.1 - 0.19 11.8 3.7 0.35 10.9 2.5 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 KOS19941.1 - 0.57 10.2 3.5 1 9.4 2.4 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 KOS19941.1 - 0.86 9.2 3.2 1.5 8.4 2.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Semialdhyde_dhC PF02774.13 KOS19942.1 - 1.8e-36 125.7 0.0 2.3e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KOS19942.1 - 1.6e-26 92.9 0.0 4.3e-26 91.5 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KOS19942.1 - 0.048 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 KOS19942.1 - 0.11 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Ipi1_N PF12333.3 KOS19943.1 - 3e-20 72.0 0.0 1e-19 70.3 0.0 1.9 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 KOS19943.1 - 0.034 14.4 0.2 0.071 13.4 0.1 1.5 1 0 0 1 1 1 0 HEAT repeats NatB_MDM20 PF09797.4 KOS19943.1 - 0.07 11.8 0.0 0.29 9.7 0.0 1.9 2 0 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit UPF0139 PF03669.8 KOS19944.1 - 0.00036 20.0 0.0 0.00043 19.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Nucleoside_tran PF01733.13 KOS19944.1 - 0.022 13.9 0.1 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 Nucleoside transporter Mg_trans_NIPA PF05653.9 KOS19945.1 - 2.2e-13 49.8 7.3 3.7e-13 49.0 5.1 1.3 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KOS19945.1 - 7.5e-06 25.9 13.8 0.00035 20.5 0.0 2.8 3 0 0 3 3 3 2 EamA-like transporter family SMC_N PF02463.14 KOS19946.1 - 9.8e-23 80.5 0.0 1.9e-22 79.5 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KOS19946.1 - 1.5e-14 54.7 43.5 1.1e-12 48.7 13.0 5.1 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.1 KOS19946.1 - 3.4e-09 37.0 0.3 4.7e-05 23.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KOS19946.1 - 0.00033 20.1 0.0 0.00068 19.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain BLOC1_2 PF10046.4 KOS19946.1 - 0.0005 20.1 0.3 0.0005 20.1 0.2 7.4 6 2 2 8 8 7 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 KOS19946.1 - 0.0044 16.2 8.6 1.7 7.7 0.0 4.7 4 2 0 4 4 4 1 Reovirus sigma C capsid protein AAA_25 PF13481.1 KOS19946.1 - 0.019 14.3 0.9 0.085 12.2 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA_22 PF13401.1 KOS19946.1 - 0.023 14.8 1.8 0.95 9.6 0.0 3.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KOS19946.1 - 0.024 13.8 0.0 0.068 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Baculo_PEP_C PF04513.7 KOS19946.1 - 0.029 14.2 15.1 0.87 9.4 0.0 5.1 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 KOS19946.1 - 7 5.2 58.9 0.11 11.0 6.6 4.9 3 1 0 4 4 4 0 Spc7 kinetochore protein AAA_17 PF13207.1 KOS19946.1 - 7.7 7.3 9.8 0.49 11.2 0.6 3.8 2 2 0 2 2 2 0 AAA domain MFS_1 PF07690.11 KOS19947.1 - 7.9e-45 153.0 42.7 1.4e-44 152.2 29.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4407 PF14362.1 KOS19947.1 - 2.6 6.9 7.9 3 6.7 0.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DUF1772 PF08592.6 KOS19949.1 - 9.4e-29 99.9 7.5 9.4e-29 99.9 5.2 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) 5TM-5TMR_LYT PF07694.7 KOS19949.1 - 0.43 9.8 7.2 22 4.3 5.0 2.3 1 1 0 1 1 1 0 5TMR of 5TMR-LYT EthD PF07110.6 KOS19950.1 - 1.8e-20 73.6 0.7 2.2e-20 73.3 0.5 1.1 1 0 0 1 1 1 1 EthD domain ketoacyl-synt PF00109.21 KOS19951.1 - 1e-70 238.1 0.3 7.2e-70 235.3 0.0 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KOS19951.1 - 2.3e-43 148.7 0.0 7.2e-43 147.1 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KOS19951.1 - 2.6e-34 117.6 1.0 5.5e-34 116.5 0.7 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KOS19951.1 - 4.3e-11 42.9 0.2 1.1e-10 41.5 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KOS19951.1 - 2.6e-05 23.3 0.1 5.5e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 KOS19951.1 - 0.0017 18.1 0.0 0.0049 16.6 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lactamase_B PF00753.22 KOS19952.1 - 1.1e-21 77.4 1.5 1.6e-21 76.8 1.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KOS19952.1 - 0.00025 20.6 0.2 0.00049 19.6 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain FAD_binding_3 PF01494.14 KOS19953.1 - 9.7e-27 93.9 0.0 2.2e-26 92.7 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KOS19953.1 - 1.2e-06 27.8 0.6 1.1e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 KOS19953.1 - 2.2e-05 23.5 0.9 0.024 13.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KOS19953.1 - 0.00019 20.5 0.4 0.021 13.7 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.9 KOS19953.1 - 0.0038 15.9 2.7 0.12 10.9 0.0 2.2 1 1 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 KOS19953.1 - 0.011 15.7 0.4 0.023 14.7 0.3 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KOS19953.1 - 0.013 15.9 1.3 1.8 9.0 0.3 3.5 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KOS19953.1 - 0.015 15.1 0.1 0.036 13.9 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KOS19953.1 - 0.043 12.6 0.0 0.3 9.8 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase DUF1420 PF07220.6 KOS19953.1 - 0.12 10.7 0.1 0.63 8.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1420) GIDA PF01134.17 KOS19953.1 - 0.18 10.6 0.0 0.4 9.4 0.0 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A polyprenyl_synt PF00348.12 KOS19955.1 - 2e-13 49.8 0.0 3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Glyco_hydro_12 PF01670.11 KOS19957.1 - 8.2e-41 139.3 0.3 8.2e-41 139.3 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 Sugar_tr PF00083.19 KOS19958.1 - 2.1e-114 382.6 32.7 2.4e-114 382.3 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS19958.1 - 3.3e-22 78.6 60.8 2.1e-19 69.4 20.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KOS19958.1 - 1.5e-07 30.1 31.0 0.00023 19.6 10.0 3.4 3 1 0 3 3 3 3 MFS/sugar transport protein Aldo_ket_red PF00248.16 KOS19959.1 - 1.3e-54 184.9 0.0 1.7e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GCIP PF13324.1 KOS19960.1 - 4.2e-05 22.9 0.8 7.3e-05 22.1 0.5 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Serglycin PF04360.7 KOS19960.1 - 0.0016 18.1 0.9 0.023 14.4 0.1 2.4 3 0 0 3 3 3 1 Serglycin CDC45 PF02724.9 KOS19960.1 - 0.9 7.4 3.1 1.2 7.0 2.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PRKCSH-like PF12999.2 KOS19961.1 - 8.8e-43 145.8 2.1 2.1e-23 82.7 0.0 2.9 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KOS19961.1 - 4.9e-30 104.0 0.9 4.9e-30 104.0 0.7 1.6 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KOS19961.1 - 2.7e-11 44.1 0.4 6.8e-11 42.8 0.3 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ADIP PF11559.3 KOS19961.1 - 0.0025 17.7 11.2 0.91 9.4 0.0 3.3 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding CASP_C PF08172.7 KOS19961.1 - 0.016 14.2 3.1 0.2 10.6 0.7 2.2 2 0 0 2 2 2 0 CASP C terminal Prefoldin_2 PF01920.15 KOS19961.1 - 0.1 12.3 12.1 0.18 11.5 1.7 3.4 3 0 0 3 3 3 0 Prefoldin subunit Fzo_mitofusin PF04799.8 KOS19961.1 - 0.21 10.9 3.8 11 5.3 0.2 2.9 3 0 0 3 3 3 0 fzo-like conserved region DivIC PF04977.10 KOS19961.1 - 0.29 10.6 9.4 0.2 11.1 0.8 3.0 3 0 0 3 3 3 0 Septum formation initiator FlxA PF14282.1 KOS19961.1 - 0.47 10.4 3.5 2.1 8.3 0.1 2.4 2 0 0 2 2 2 0 FlxA-like protein FliJ PF02050.11 KOS19961.1 - 0.63 10.1 10.3 0.068 13.2 1.4 2.9 3 0 0 3 3 3 0 Flagellar FliJ protein Tup_N PF08581.5 KOS19961.1 - 0.95 9.7 7.3 6.2 7.0 0.0 3.0 3 0 0 3 3 3 0 Tup N-terminal MerR-DNA-bind PF09278.6 KOS19961.1 - 1.8 8.9 7.9 2.3 8.6 1.1 3.1 3 0 0 3 3 3 0 MerR, DNA binding Mnd1 PF03962.10 KOS19961.1 - 2.2 7.9 6.8 0.59 9.7 1.7 2.2 2 0 0 2 2 2 0 Mnd1 family Filament PF00038.16 KOS19961.1 - 2.9 7.2 18.1 0.84 9.0 2.9 2.7 2 1 0 2 2 2 0 Intermediate filament protein Prefoldin PF02996.12 KOS19961.1 - 4.4 6.9 8.2 13 5.4 0.3 3.1 3 0 0 3 3 3 0 Prefoldin subunit Methyltransf_12 PF08242.7 KOS19962.1 - 1.8e-07 31.5 0.0 9.8e-07 29.1 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS19962.1 - 9.1e-07 28.7 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS19962.1 - 1.9e-06 28.4 0.0 3.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS19962.1 - 4.5e-06 27.0 0.0 4.4e-05 23.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Serglycin PF04360.7 KOS19962.1 - 0.00018 21.2 0.6 0.00037 20.2 0.4 1.5 1 0 0 1 1 1 1 Serglycin Methyltransf_26 PF13659.1 KOS19962.1 - 0.00071 19.5 0.0 0.0013 18.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS19962.1 - 0.0024 18.1 0.0 0.01 16.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS19962.1 - 0.056 13.0 0.0 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain NodS PF05401.6 KOS19962.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.9 KOS19962.1 - 0.098 12.0 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain FAT PF02259.18 KOS19963.1 - 4.5e-128 427.1 5.2 9.7e-128 426.0 3.6 1.6 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.3 KOS19963.1 - 1.6e-63 213.4 2.1 1.3e-62 210.4 0.3 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 KOS19963.1 - 1.1e-62 211.5 0.4 2.3e-62 210.5 0.3 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 KOS19963.1 - 3.7e-43 145.6 0.2 3.7e-43 145.6 0.1 3.2 4 0 0 4 4 4 1 Rapamycin binding domain HEAT_2 PF13646.1 KOS19963.1 - 1.4e-20 73.3 1.7 0.00013 22.1 0.0 8.6 5 3 1 7 7 7 3 HEAT repeats HEAT PF02985.17 KOS19963.1 - 2.8e-14 51.8 18.4 0.059 13.4 0.0 12.5 14 0 0 14 14 14 3 HEAT repeat FATC PF02260.15 KOS19963.1 - 3.6e-14 51.9 0.1 8.2e-14 50.7 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 KOS19963.1 - 3e-10 40.2 16.4 2e-05 24.9 0.0 11.2 9 3 3 12 12 11 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KOS19963.1 - 3.1e-08 33.8 0.1 21 5.5 0.0 7.7 6 1 1 7 7 7 0 Vacuolar 14 Fab1-binding region Baculo_PEP_C PF04513.7 KOS19963.1 - 0.0049 16.7 1.0 0.14 11.9 0.1 3.2 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_1 PF00515.23 KOS19963.1 - 0.76 9.4 3.3 71 3.2 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KOS19963.1 - 6 7.0 10.2 48 4.2 0.2 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Actin PF00022.14 KOS19964.1 - 2.8e-95 319.0 0.0 3.3e-95 318.8 0.0 1.1 1 0 0 1 1 1 1 Actin F-box-like PF12937.2 KOS19965.1 - 0.0021 17.7 1.6 0.03 14.0 0.1 2.6 2 0 0 2 2 2 1 F-box-like Baculo_IE-1 PF05290.6 KOS19966.1 - 0.15 11.8 1.9 0.22 11.2 1.3 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Tetraspannin PF00335.15 KOS19967.1 - 1.2e-08 34.5 4.5 1.7e-08 34.0 3.1 1.2 1 0 0 1 1 1 1 Tetraspanin family TctB PF07331.6 KOS19967.1 - 3.4 7.3 10.7 1.4 8.5 4.0 2.6 2 1 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family Ctr PF04145.10 KOS19968.1 - 2.3e-31 108.7 0.0 2.7e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Sensor PF13796.1 KOS19968.1 - 0.36 10.4 7.0 2.3 7.7 0.6 2.3 2 0 0 2 2 2 0 Putative sensor SRF-TF PF00319.13 KOS19969.1 - 8.1e-24 82.6 0.4 1.2e-23 82.0 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 KOS19969.1 - 0.0057 14.7 0.4 0.0066 14.5 0.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Pkinase PF00069.20 KOS19970.1 - 2.2e-60 204.0 0.1 2.6e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS19970.1 - 9.1e-32 110.1 0.0 1.2e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS19970.1 - 1.2e-07 31.0 0.0 1.5e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KOS19970.1 - 0.00012 21.2 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KOS19970.1 - 0.0033 17.1 0.1 0.0091 15.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KOS19970.1 - 0.0082 15.7 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RRM_1 PF00076.17 KOS19972.1 - 2.2e-79 261.0 5.0 1.1e-18 66.6 0.2 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS19972.1 - 3.7e-54 180.5 0.6 4.2e-14 52.2 0.0 5.7 6 0 0 6 6 6 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS19972.1 - 2.3e-40 136.2 0.2 3.9e-10 39.4 0.0 5.8 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KOS19972.1 - 2.8e-27 94.1 1.9 1.1e-26 92.3 1.2 2.0 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 KOS19972.1 - 0.001 18.8 0.4 8 6.3 0.0 4.2 3 1 0 3 3 3 2 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 KOS19972.1 - 0.0036 17.4 4.7 4.6 7.5 0.0 4.5 5 0 0 5 5 5 1 Cobalamin biosynthesis central region Nab6_mRNP_bdg PF10567.4 KOS19972.1 - 0.016 14.2 1.8 0.055 12.4 0.5 2.1 2 0 0 2 2 2 0 RNA-recognition motif TC1 PF15063.1 KOS19972.1 - 0.041 13.4 0.6 11 5.6 0.0 3.0 3 0 0 3 3 3 0 Thyroid cancer protein 1 OB_RNB PF08206.6 KOS19972.1 - 0.045 13.2 2.8 5.8 6.5 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Limkain-b1 PF11608.3 KOS19972.1 - 0.11 12.2 2.0 22 4.8 0.0 3.5 3 0 0 3 3 3 0 Limkain b1 TBP PF00352.16 KOS19973.1 - 2e-55 184.1 0.1 2.5e-35 119.6 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KOS19973.1 - 0.00026 20.9 0.0 0.55 10.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DAO PF01266.19 KOS19974.1 - 3.9e-29 101.6 8.9 3.6e-28 98.4 6.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KOS19974.1 - 0.00029 20.7 0.0 0.0011 18.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KOS19974.1 - 0.0014 18.4 1.5 0.059 13.1 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding GMC_oxred_N PF00732.14 KOS19974.1 - 0.042 12.9 0.4 0.11 11.6 0.1 1.8 3 0 0 3 3 3 0 GMC oxidoreductase HECT PF00632.20 KOS19975.1 - 3e-81 273.0 0.0 3.8e-81 272.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) OmdA PF13376.1 KOS19975.1 - 0.076 12.6 1.4 1.5 8.5 0.9 2.4 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated ETF_QO PF05187.8 KOS19976.1 - 3e-42 143.0 0.0 4.6e-42 142.4 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 KOS19976.1 - 5.4e-09 35.4 2.5 6.1e-05 22.0 0.1 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KOS19976.1 - 5.7e-08 32.6 0.0 1.3e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KOS19976.1 - 2.2e-05 23.5 2.0 0.0065 15.3 1.1 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 KOS19976.1 - 4.6e-05 22.6 0.0 7.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KOS19976.1 - 7.8e-05 21.8 0.0 0.001 18.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KOS19976.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KOS19976.1 - 0.00049 18.6 0.5 0.00073 18.1 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KOS19976.1 - 0.00082 18.5 0.2 0.0013 17.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KOS19976.1 - 0.00085 19.1 0.3 0.0041 16.9 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KOS19976.1 - 0.0032 17.5 0.0 0.0053 16.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KOS19976.1 - 0.0048 15.5 0.1 0.36 9.4 0.1 2.2 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 KOS19976.1 - 0.0049 17.2 0.0 7.5 7.0 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 KOS19976.1 - 0.005 17.1 1.3 0.011 16.0 0.9 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 KOS19976.1 - 0.04 12.8 0.5 0.058 12.3 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KOS19976.1 - 0.19 10.5 0.5 0.28 10.0 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_16 PF10294.4 KOS19978.1 - 2.6e-14 53.0 0.0 1.6e-10 40.7 0.0 2.1 1 1 1 2 2 2 2 Putative methyltransferase PrmA PF06325.8 KOS19978.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KOS19978.1 - 0.033 14.7 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Surp PF01805.15 KOS19979.1 - 5e-15 54.8 0.0 1.1e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Surp module RRM_6 PF14259.1 KOS19979.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Copper-fist PF00649.13 KOS19980.1 - 3.6e-18 64.4 1.0 3.6e-18 64.4 0.7 2.0 2 0 0 2 2 2 1 Copper fist DNA binding domain BPL_N PF09825.4 KOS19981.1 - 5.2e-124 413.7 0.0 6.5e-124 413.4 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KOS19981.1 - 1.5e-18 67.0 0.0 2.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Mgm101p PF06420.7 KOS19982.1 - 2.3e-83 277.7 0.1 2.8e-83 277.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Pex14_N PF04695.8 KOS19982.1 - 0.25 11.3 3.9 1.1 9.3 2.2 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TB2_DP1_HVA22 PF03134.14 KOS19983.1 - 4.8e-30 103.1 8.4 7e-30 102.6 5.9 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family CASP_C PF08172.7 KOS19983.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 CASP C terminal Serglycin PF04360.7 KOS19984.1 - 0.32 10.6 20.5 0.032 13.9 8.9 2.3 1 1 1 2 2 2 0 Serglycin WSC PF01822.14 KOS19986.1 - 8.9e-07 28.7 6.5 4e-06 26.6 4.5 2.2 1 1 0 1 1 1 1 WSC domain DUF2865 PF11064.3 KOS19986.1 - 0.0044 16.8 2.5 0.0044 16.8 1.7 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2865) CENP-T PF15511.1 KOS19986.1 - 0.036 13.3 17.4 0.044 13.0 12.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RR_TM4-6 PF06459.7 KOS19986.1 - 0.042 13.7 15.1 0.062 13.1 10.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF812 PF05667.6 KOS19986.1 - 0.091 11.2 11.8 0.1 11.0 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Daxx PF03344.10 KOS19986.1 - 0.17 10.3 19.1 0.21 10.0 13.2 1.2 1 0 0 1 1 1 0 Daxx Family PIH1 PF08190.7 KOS19986.1 - 0.21 10.9 12.1 0.31 10.4 8.4 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 EIIBC-GUT_N PF03612.9 KOS19986.1 - 0.25 10.9 5.4 0.34 10.5 3.2 1.5 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Raftlin PF15250.1 KOS19986.1 - 0.43 9.0 7.8 0.58 8.6 5.4 1.2 1 0 0 1 1 1 0 Raftlin DDHD PF02862.12 KOS19986.1 - 0.47 10.2 8.3 0.68 9.6 5.8 1.4 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.5 KOS19986.1 - 0.53 10.2 13.3 0.8 9.6 9.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.7 KOS19986.1 - 0.82 7.5 18.4 1.1 7.1 12.8 1.1 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.1 KOS19986.1 - 0.85 9.0 16.8 1.4 8.3 11.6 1.4 1 0 0 1 1 1 0 Spore coat protein CotO MCPVI PF02993.9 KOS19986.1 - 1.1 9.3 9.5 1.8 8.6 6.6 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Asp-B-Hydro_N PF05279.6 KOS19986.1 - 1.3 8.8 19.0 1.8 8.3 13.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FAM176 PF14851.1 KOS19986.1 - 1.7 8.2 10.9 2.9 7.5 7.6 1.4 1 0 0 1 1 1 0 FAM176 family DUF2052 PF09747.4 KOS19986.1 - 2.8 7.8 19.8 4.3 7.2 13.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Pox_Ag35 PF03286.9 KOS19986.1 - 3.3 7.2 11.0 5.2 6.5 7.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Lin-8 PF03353.10 KOS19986.1 - 4.3 6.5 15.6 5.9 6.0 10.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.9 KOS19986.1 - 5.1 5.0 14.7 7 4.5 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 KOS19986.1 - 7.5 6.5 19.7 12 5.9 13.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Pox_RNA_Pol_19 PF05320.7 KOS19986.1 - 7.9 6.2 9.5 14 5.4 6.6 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Methyltransf_23 PF13489.1 KOS19987.1 - 7.8e-22 77.7 0.1 1.1e-21 77.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS19987.1 - 2.2e-12 47.3 0.0 4.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS19987.1 - 1.5e-10 41.3 0.0 1.6e-09 38.1 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS19987.1 - 1.2e-09 38.7 0.0 3.2e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS19987.1 - 1.2e-08 34.6 0.0 1.7e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS19987.1 - 1.4e-06 28.6 0.0 3.3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KOS19987.1 - 4.1e-05 22.7 0.0 0.00028 19.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 KOS19987.1 - 0.0024 17.0 0.0 0.01 14.9 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_17 PF12692.2 KOS19987.1 - 0.0043 16.7 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-methionine methyltransferase FtsJ PF01728.14 KOS19987.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CheR PF01739.13 KOS19987.1 - 0.017 14.4 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MetW PF07021.7 KOS19987.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 KOS19987.1 - 0.077 13.0 0.0 0.45 10.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KOS19987.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 KOS19987.1 - 0.15 11.1 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Arm PF00514.18 KOS19989.1 - 0.001 18.8 0.7 0.29 11.0 0.2 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KOS19989.1 - 0.037 14.2 10.6 0.082 13.2 0.2 4.0 3 1 2 5 5 5 0 HEAT repeats Pam16 PF03656.8 KOS19990.1 - 3.6e-29 101.1 0.2 4.5e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 Pam16 UFD1 PF03152.9 KOS19991.1 - 1.3e-23 83.0 0.0 1.4e-22 79.7 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 PRP21_like_P PF12230.3 KOS19991.1 - 0.3 10.5 0.8 0.58 9.6 0.4 1.6 1 1 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein GFA PF04828.9 KOS19993.1 - 1.9e-06 27.7 0.5 2.8e-06 27.1 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Phytase PF02333.10 KOS19994.1 - 0.061 12.0 0.1 0.076 11.7 0.1 1.1 1 0 0 1 1 1 0 Phytase Methyltransf_16 PF10294.4 KOS19996.1 - 3.4e-21 75.4 0.0 9.2e-21 74.0 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KOS19996.1 - 0.0032 16.8 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ribosomal_60s PF00428.14 KOS19996.1 - 3.8 7.9 10.7 1 9.7 0.8 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein ABC2_membrane PF01061.19 KOS19997.1 - 4.2e-78 261.3 55.9 4.3e-41 140.4 15.4 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KOS19997.1 - 8e-36 123.3 0.0 3.5e-17 62.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KOS19997.1 - 7.6e-25 86.5 0.0 3.1e-24 84.6 0.0 2.1 1 0 0 1 1 1 1 CDR ABC transporter AAA_25 PF13481.1 KOS19997.1 - 2.6e-07 30.2 0.0 0.005 16.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.2 KOS19997.1 - 3.2e-07 29.7 44.3 0.00033 19.8 12.6 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 KOS19997.1 - 1e-06 28.7 0.0 0.0027 17.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KOS19997.1 - 1.2e-06 29.3 0.0 0.038 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_trans_N PF14510.1 KOS19997.1 - 1.4e-06 28.2 0.0 3.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 KOS19997.1 - 3.1e-06 27.3 0.0 0.032 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KOS19997.1 - 3.5e-05 23.9 0.0 0.15 12.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KOS19997.1 - 6.2e-05 22.4 0.1 0.0039 16.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 KOS19997.1 - 7.6e-05 22.2 0.6 0.012 15.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KOS19997.1 - 0.00013 21.9 0.1 0.016 15.2 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain UPF0079 PF02367.12 KOS19997.1 - 0.00031 20.3 0.3 0.66 9.6 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KOS19997.1 - 0.0009 18.9 0.1 1.7 8.4 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain DUF258 PF03193.11 KOS19997.1 - 0.0014 17.8 0.0 0.01 15.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KOS19997.1 - 0.0015 18.8 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KOS19997.1 - 0.0017 18.3 0.1 0.042 13.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KOS19997.1 - 0.002 17.3 0.0 0.11 11.7 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 KOS19997.1 - 0.003 17.2 0.2 2.6 7.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain FtsK_SpoIIIE PF01580.13 KOS19997.1 - 0.011 15.1 0.0 0.9 8.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KOS19997.1 - 0.027 13.9 0.1 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 KOS19997.1 - 0.032 13.9 0.0 3.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 KOS19997.1 - 0.044 13.9 0.1 12 6.0 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 KOS19997.1 - 0.045 12.8 0.0 4.6 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 KOS19997.1 - 0.045 13.2 0.2 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KOS19997.1 - 0.099 13.1 0.0 7.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 KOS19997.1 - 0.15 11.5 0.2 8.5 5.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KOS19997.1 - 0.59 10.4 0.0 0.59 10.4 0.0 2.2 3 0 0 3 3 1 0 AAA domain Fungal_trans PF04082.13 KOS19999.1 - 5.8e-16 58.1 0.1 8.7e-16 57.5 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Apc5 PF12862.2 KOS19999.1 - 0.1 12.4 0.1 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 Oxidored-like PF09791.4 KOS20000.1 - 1.1e-25 88.8 2.6 1.8e-25 88.0 1.8 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Pribosyltran PF00156.22 KOS20001.1 - 8.8e-10 38.3 0.4 5.3e-09 35.8 0.3 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DPM3 PF08285.6 KOS20002.1 - 2.1e-30 104.4 0.1 2.3e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF605 PF04652.11 KOS20004.1 - 7.1 5.9 21.3 9.6 5.4 14.8 1.3 1 0 0 1 1 1 0 Vta1 like p450 PF00067.17 KOS20005.1 - 3.6e-54 184.0 0.0 4.6e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nudix_N PF12535.3 KOS20005.1 - 0.034 13.6 0.0 0.24 10.8 0.0 2.2 2 0 0 2 2 2 0 Hydrolase of X-linked nucleoside diphosphate N terminal DUF3948 PF13134.1 KOS20005.1 - 0.073 12.5 0.1 0.073 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) Glyco_hydro_1 PF00232.13 KOS20006.1 - 7.2e-142 472.7 0.0 8.1e-142 472.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 KOS20006.1 - 0.00017 21.0 0.0 0.00044 19.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core COPI_C PF06957.6 KOS20008.1 - 0.0053 15.3 10.7 0.007 14.9 7.4 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Paf1 PF03985.8 KOS20008.1 - 1.1 7.9 4.1 1.4 7.5 2.8 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.9 KOS20008.1 - 2.5 6.0 4.9 3.1 5.7 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 KOS20008.1 - 4.3 5.6 7.1 5.8 5.2 4.9 1.1 1 0 0 1 1 1 0 Daxx Family TRAPP PF04051.11 KOS20010.1 - 8.4e-37 126.0 0.0 1e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.3 KOS20010.1 - 0.083 11.7 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A WD40 PF00400.27 KOS20011.1 - 1.1e-54 180.4 2.0 4.3e-09 35.9 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KOS20011.1 - 0.014 14.2 1.2 1.8 7.2 0.3 3.3 1 1 2 3 3 3 0 Nup133 N terminal like SGL PF08450.7 KOS20011.1 - 0.015 14.6 0.6 0.3 10.4 0.1 2.7 1 1 3 4 4 4 0 SMP-30/Gluconolaconase/LRE-like region Nup160 PF11715.3 KOS20011.1 - 0.066 11.3 0.3 0.57 8.2 0.0 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.7 KOS20011.1 - 0.12 12.0 0.8 0.96 9.1 0.1 2.5 1 1 1 2 2 2 0 WD40-like Beta Propeller Repeat Glyco_hydro_18 PF00704.23 KOS20012.1 - 4e-18 65.9 1.2 8.9e-17 61.5 0.2 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 DUF1993 PF09351.5 KOS20013.1 - 2.2e-20 73.2 0.0 2.5e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Fungal_trans_2 PF11951.3 KOS20014.1 - 5.8e-05 21.8 2.2 6.2e-05 21.7 0.8 1.5 1 1 1 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.8 KOS20015.1 - 7.4e-46 156.4 5.8 8.9e-46 156.1 4.0 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF2165 PF09933.4 KOS20015.1 - 0.17 11.5 5.0 0.063 13.0 1.2 1.9 1 1 1 2 2 2 0 Predicted small integral membrane protein (DUF2165) adh_short PF00106.20 KOS20016.1 - 1.6e-21 76.9 0.0 2e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS20016.1 - 1.8e-07 31.2 0.0 2.5e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS20016.1 - 7.2e-07 29.0 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KOS20016.1 - 0.0003 20.3 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KOS20016.1 - 0.0006 20.1 0.1 0.0012 19.1 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 KOS20016.1 - 0.0027 16.6 0.1 0.004 16.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KOS20016.1 - 0.0032 17.5 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Phosphoesterase PF04185.9 KOS20017.1 - 1.2e-60 205.7 1.7 2.4e-60 204.7 1.2 1.5 1 1 0 1 1 1 1 Phosphoesterase family Dynamin_N PF00350.18 KOS20018.1 - 3.9e-21 75.5 0.3 5.8e-15 55.5 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Dynamin_M PF01031.15 KOS20018.1 - 4.3e-14 51.9 0.0 1.7e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KOS20018.1 - 1.1e-06 28.6 0.0 3.3e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KOS20018.1 - 0.0026 18.2 0.2 0.01 16.3 0.1 2.1 1 1 0 1 1 1 1 Miro-like protein GED PF02212.13 KOS20018.1 - 0.011 15.6 0.5 0.036 13.9 0.4 1.9 1 0 0 1 1 1 0 Dynamin GTPase effector domain FeoB_N PF02421.13 KOS20018.1 - 0.024 13.9 0.0 1.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Zeta_toxin PF06414.7 KOS20018.1 - 0.045 12.8 0.5 4.1 6.4 0.0 3.2 4 0 0 4 4 4 0 Zeta toxin ABC_tran PF00005.22 KOS20018.1 - 0.05 13.9 0.2 0.21 11.9 0.0 2.1 2 1 0 2 2 2 0 ABC transporter DUF3932 PF13068.1 KOS20018.1 - 0.16 12.1 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) SLAC1 PF03595.12 KOS20019.1 - 1.8e-51 174.7 42.4 2.3e-51 174.4 29.4 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel MFS_1 PF07690.11 KOS20020.1 - 5.9e-25 87.7 41.6 1.2e-18 66.9 12.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KOS20020.1 - 0.00031 20.7 11.6 0.0041 17.1 0.8 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF1228) RGS PF00615.14 KOS20021.1 - 9.5e-05 22.4 0.0 0.00018 21.6 0.0 1.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain Na_H_Exchanger PF00999.16 KOS20022.1 - 2.1e-43 148.3 37.4 4.8e-43 147.1 17.8 2.1 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family Peptidase_M14 PF00246.19 KOS20023.1 - 4.4e-68 229.9 0.0 6.1e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KOS20023.1 - 3.9e-05 23.2 0.0 9.9e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Glyco_transf_54 PF04666.8 KOS20024.1 - 3e-09 36.0 0.0 4.7e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF4630 PF15443.1 KOS20024.1 - 0.068 12.9 0.1 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) Cation_ATPase_C PF00689.16 KOS20025.1 - 4.1e-42 143.7 5.6 4.1e-42 143.7 3.9 2.9 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.15 KOS20025.1 - 1.7e-33 115.5 8.7 2.2e-33 115.2 3.8 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KOS20025.1 - 3.6e-30 105.9 0.0 3.3e-29 102.8 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS20025.1 - 1.2e-16 60.4 0.0 2.4e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KOS20025.1 - 6.8e-15 55.7 0.1 2e-14 54.2 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KOS20025.1 - 4e-14 51.8 0.0 1.1e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KOS20025.1 - 0.00031 20.3 0.1 0.0006 19.4 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1777 PF08648.7 KOS20025.1 - 0.019 14.6 7.3 0.036 13.8 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) HORMA PF02301.13 KOS20026.1 - 9.2e-43 146.1 0.0 1.1e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 HORMA domain DEAD PF00270.24 KOS20027.1 - 1.1e-50 171.3 0.0 5.8e-48 162.5 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS20027.1 - 1e-28 98.9 0.0 3.7e-28 97.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain MIP-T3 PF10243.4 KOS20027.1 - 0.002 16.6 56.7 0.003 16.1 39.3 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF2413 PF10310.4 KOS20027.1 - 8 5.1 41.6 16 4.1 28.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) bZIP_1 PF00170.16 KOS20028.1 - 0.00086 19.2 15.3 0.0031 17.4 6.0 2.2 1 1 1 2 2 2 2 bZIP transcription factor Mnd1 PF03962.10 KOS20028.1 - 0.009 15.7 2.3 0.013 15.2 1.6 1.1 1 0 0 1 1 1 1 Mnd1 family DUF904 PF06005.7 KOS20028.1 - 0.028 14.6 4.5 0.047 13.9 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF1199 PF06712.6 KOS20028.1 - 2.8 7.8 4.6 30 4.5 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) BMFP PF04380.8 KOS20028.1 - 8 6.6 8.3 0.52 10.4 1.0 2.1 2 0 0 2 2 2 0 Membrane fusogenic activity Glyco_hydro_3 PF00933.16 KOS20029.1 - 4e-80 268.9 0.0 6e-80 268.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KOS20029.1 - 2.9e-68 229.8 0.0 5.9e-68 228.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KOS20029.1 - 4.3e-24 84.2 0.1 1e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KOS20029.1 - 4.8e-14 52.2 0.0 8.5e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 PA14 domain FTA4 PF13093.1 KOS20030.1 - 4.8e-33 114.3 0.0 5.4e-32 110.9 0.0 1.9 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 RPE65 PF03055.10 KOS20033.1 - 3.7e-113 378.6 0.0 4.2e-113 378.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SR-25 PF10500.4 KOS20033.1 - 0.11 11.9 13.2 0.17 11.3 9.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NifU_N PF01592.11 KOS20034.1 - 3.5e-52 175.6 0.1 4.7e-52 175.2 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain UCH PF00443.24 KOS20035.1 - 2.4e-42 144.9 0.0 3.5e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KOS20035.1 - 4.9e-23 81.0 11.0 4.2e-20 71.6 1.2 2.9 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 KOS20035.1 - 9.7e-20 69.8 0.0 3.2e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 KOS20035.1 - 1.3e-15 57.6 0.0 3.7e-13 49.5 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Prim_Zn_Ribbon PF08273.7 KOS20035.1 - 0.61 10.2 0.0 0.61 10.2 0.0 3.8 4 1 0 4 4 4 0 Zinc-binding domain of primase-helicase OxoDH_E1alpha_N PF12573.3 KOS20036.1 - 0.13 11.8 0.2 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal ABC_tran PF00005.22 KOS20037.1 - 1e-49 168.3 0.8 5.3e-25 88.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KOS20037.1 - 6.7e-25 87.8 47.0 6.3e-14 51.7 15.6 3.1 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 KOS20037.1 - 1.2e-23 84.4 1.0 2.6e-06 27.6 0.0 4.5 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 KOS20037.1 - 6e-10 38.5 3.5 2.8e-05 23.5 0.2 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KOS20037.1 - 1.5e-08 35.1 1.8 0.0015 18.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KOS20037.1 - 2.2e-06 27.0 4.7 0.041 13.1 0.1 4.2 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KOS20037.1 - 7.8e-05 21.9 1.0 0.29 10.3 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 KOS20037.1 - 0.00045 19.3 0.0 0.67 8.9 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 KOS20037.1 - 0.0012 18.6 0.3 5 7.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 KOS20037.1 - 0.0013 18.3 2.5 0.083 12.4 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KOS20037.1 - 0.0028 17.6 4.9 1 9.3 0.1 3.4 4 0 0 4 4 4 2 AAA ATPase domain AAA_19 PF13245.1 KOS20037.1 - 0.0032 17.1 3.1 1.6 8.5 0.2 3.7 3 0 0 3 3 3 1 Part of AAA domain AAA_25 PF13481.1 KOS20037.1 - 0.013 14.9 0.7 2.7 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KOS20037.1 - 0.014 14.8 1.2 2 7.8 0.1 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 KOS20037.1 - 0.014 14.8 0.8 2 7.7 0.1 2.9 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 KOS20037.1 - 0.018 14.1 0.8 1.6 7.7 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 KOS20037.1 - 0.026 14.6 1.5 4.3 7.4 0.1 3.5 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.1 KOS20037.1 - 0.027 14.4 0.4 2 8.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KOS20037.1 - 0.061 12.0 0.6 8.2 5.1 0.1 2.4 2 0 0 2 2 2 0 ArgK protein AAA_14 PF13173.1 KOS20037.1 - 0.15 11.9 0.1 19 5.1 0.0 3.2 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 KOS20037.1 - 0.18 12.6 0.3 25 5.7 0.1 2.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KOS20037.1 - 0.24 10.2 1.0 0.35 9.7 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 KOS20037.1 - 0.27 11.7 0.1 5.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 KOS20037.1 - 0.28 10.8 0.2 8.6 6.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KOS20037.1 - 0.5 10.1 2.8 14 5.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Acyltransferase PF01553.16 KOS20038.1 - 4.6e-10 39.0 0.0 2.6e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Suc_Fer-like PF06999.7 KOS20039.1 - 1.1e-29 104.1 0.0 2.3e-25 89.9 0.0 2.7 2 1 1 3 3 3 2 Sucrase/ferredoxin-like Nop14 PF04147.7 KOS20039.1 - 0.0013 16.7 8.2 0.0016 16.5 5.7 1.0 1 0 0 1 1 1 1 Nop14-like family TRAP_alpha PF03896.11 KOS20039.1 - 0.092 11.7 8.3 0.13 11.2 5.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Zip PF02535.17 KOS20039.1 - 0.18 10.7 0.7 0.27 10.2 0.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CobT PF06213.7 KOS20039.1 - 0.2 10.7 16.0 0.5 9.4 11.3 1.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Trypan_PARP PF05887.6 KOS20039.1 - 0.33 10.7 19.1 0.57 9.9 13.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Spore_coat_CotO PF14153.1 KOS20039.1 - 0.79 9.1 12.9 1.1 8.6 9.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Radial_spoke PF04712.7 KOS20039.1 - 0.94 8.1 15.4 1.3 7.7 10.7 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Daxx PF03344.10 KOS20039.1 - 0.97 7.8 22.4 1.3 7.3 15.5 1.1 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 KOS20039.1 - 1 9.7 9.1 1.8 8.9 6.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fer4_13 PF13370.1 KOS20039.1 - 1.8 9.0 0.0 1.8 9.0 0.0 3.4 3 1 0 3 3 2 0 4Fe-4S single cluster domain RR_TM4-6 PF06459.7 KOS20039.1 - 2.1 8.1 14.0 3.2 7.5 9.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.3 KOS20039.1 - 2.4 6.6 9.3 3.8 6.0 6.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pox_Ag35 PF03286.9 KOS20039.1 - 2.7 7.4 14.5 4.1 6.8 10.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_polI_A34 PF08208.6 KOS20039.1 - 4.7 6.8 18.3 7.1 6.2 12.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Ycf1 PF05758.7 KOS20039.1 - 9.1 3.8 10.9 12 3.4 7.6 1.0 1 0 0 1 1 1 0 Ycf1 Chromo_shadow PF01393.14 KOS20041.1 - 4.3e-14 52.1 0.6 5.2e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 KOS20041.1 - 3.4e-11 42.6 0.8 3.4e-11 42.6 0.6 2.9 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1501 PF07394.7 KOS20041.1 - 0.011 14.6 0.1 0.014 14.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF2457 PF10446.4 KOS20041.1 - 0.056 12.1 12.1 0.08 11.6 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) COX15-CtaA PF02628.10 KOS20042.1 - 2.4e-99 332.0 7.3 2.9e-99 331.7 5.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Utp14 PF04615.8 KOS20043.1 - 5.7e-173 576.9 63.2 5.7e-173 576.9 43.8 2.3 1 1 1 2 2 2 1 Utp14 protein Mlo PF03094.10 KOS20043.1 - 0.26 9.3 0.1 2.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Mlo family Glyco_hydro_81 PF03639.8 KOS20044.1 - 1.8e-117 393.1 0.0 2.3e-117 392.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 DnaJ PF00226.26 KOS20045.1 - 2.5e-22 78.3 1.4 1e-21 76.4 1.0 2.1 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.11 KOS20047.1 - 2.2e-32 112.1 21.8 2e-16 59.7 5.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS20047.1 - 2.7e-05 22.9 15.5 0.0018 16.9 4.1 3.0 2 2 1 3 3 3 3 Sugar (and other) transporter MFS_2 PF13347.1 KOS20047.1 - 4.6e-05 21.9 20.3 0.027 12.8 3.1 3.6 3 1 0 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 KOS20047.1 - 0.0036 17.0 3.1 0.12 12.2 0.8 2.7 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.15 KOS20047.1 - 0.072 11.1 7.2 0.11 10.5 0.2 3.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 KOS20049.1 - 8.4e-110 367.4 24.1 9.6e-110 367.2 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS20049.1 - 1.1e-16 60.5 34.0 1.1e-16 60.5 23.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily EBP PF05241.7 KOS20049.1 - 0.4 9.6 7.5 0.73 8.8 5.2 1.3 1 0 0 1 1 1 0 Emopamil binding protein DUF3154 PF11351.3 KOS20049.1 - 7.7 6.2 9.2 2.7 7.7 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3154) MCM PF00493.18 KOS20050.1 - 3.5e-121 404.0 0.0 6.5e-121 403.1 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KOS20050.1 - 1.8e-32 112.5 33.3 1.8e-32 112.5 23.1 2.1 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KOS20050.1 - 1.3e-20 74.0 0.1 2.9e-20 72.9 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KOS20050.1 - 1.5e-07 30.8 0.0 5.4e-06 25.7 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KOS20050.1 - 8.4e-06 25.5 0.0 1.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KOS20050.1 - 0.0043 16.5 0.2 0.026 14.0 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KOS20050.1 - 0.0069 15.9 0.1 0.037 13.6 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) zf-TFIIB PF13453.1 KOS20050.1 - 0.066 12.4 1.2 0.14 11.3 0.8 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger Ctr PF04145.10 KOS20051.1 - 0.16 12.0 0.1 0.39 10.7 0.0 1.7 1 1 1 2 2 2 0 Ctr copper transporter family Host_attach PF10116.4 KOS20051.1 - 1.3 9.2 5.0 0.72 10.0 1.8 1.7 2 0 0 2 2 2 0 Protein required for attachment to host cells Carboxyl_trans PF01039.17 KOS20052.1 - 1.3e-142 475.6 0.2 1.6e-142 475.3 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 KOS20052.1 - 0.0066 15.6 0.4 0.22 10.7 0.0 2.5 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.19 KOS20053.1 - 2.1e-42 144.7 2.1 3.6e-42 143.9 1.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KOS20053.1 - 7e-31 107.1 0.2 1.5e-30 106.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KOS20053.1 - 2.3e-17 62.2 0.0 5.7e-17 60.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KOS20053.1 - 3.5e-14 53.1 1.0 7.8e-14 52.0 0.7 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KOS20053.1 - 0.005 16.2 0.1 0.025 13.9 0.0 2.1 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_ox_N PF14749.1 KOS20053.1 - 0.095 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal His_Phos_1 PF00300.17 KOS20054.1 - 6.3e-17 62.1 0.0 8.2e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Zn_clus PF00172.13 KOS20057.1 - 2.1e-07 30.7 11.5 3.8e-07 29.9 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med15 PF09606.5 KOS20057.1 - 0.0011 17.2 106.9 0.0021 16.3 74.1 1.4 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 KOS20057.1 - 0.0044 16.9 52.5 0.0044 16.9 36.4 1.8 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Mem_trans PF03547.13 KOS20057.1 - 0.03 12.6 8.2 0.036 12.3 5.6 1.3 1 0 0 1 1 1 0 Membrane transport protein PAT1 PF09770.4 KOS20057.1 - 0.09 10.9 86.0 0.13 10.4 59.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S46 PF10459.4 KOS20057.1 - 0.41 9.0 27.2 0.56 8.5 18.9 1.2 1 0 0 1 1 1 0 Peptidase S46 PLRV_ORF5 PF01690.12 KOS20057.1 - 2.6 7.0 36.9 4.2 6.3 25.6 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4045 PF13254.1 KOS20057.1 - 3.2 6.9 33.7 5.8 6.0 23.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Asp-B-Hydro_N PF05279.6 KOS20057.1 - 4.6 7.0 31.5 6.9 6.4 21.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF940 PF06082.6 KOS20057.1 - 9.4 4.6 27.8 12 4.2 19.3 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) SUFU_C PF12470.3 KOS20058.1 - 0.54 9.8 3.7 0.41 10.2 0.2 2.2 2 1 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain GTP_EFTU PF00009.22 KOS20059.1 - 3.8e-48 163.4 0.0 5.5e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KOS20059.1 - 2.4e-40 136.7 1.9 4e-40 136.0 1.3 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KOS20059.1 - 3.9e-19 68.2 0.0 7.1e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KOS20059.1 - 7e-05 22.5 0.0 0.00018 21.3 0.0 1.7 1 1 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KOS20059.1 - 0.00014 21.8 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 KOS20059.1 - 0.00073 19.6 0.1 0.0024 17.9 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Ras PF00071.17 KOS20059.1 - 0.0012 18.3 0.0 0.0058 16.0 0.0 2.0 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KOS20059.1 - 0.0077 16.7 0.0 0.026 15.0 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 KOS20059.1 - 0.085 12.0 0.0 0.22 10.7 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MIT PF04212.13 KOS20060.1 - 4.4e-10 39.2 1.8 8.4e-10 38.3 1.3 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Pou PF00157.12 KOS20060.1 - 0.066 12.8 0.0 0.4 10.3 0.0 2.2 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain vATP-synt_E PF01991.13 KOS20061.1 - 1.4e-60 204.0 5.3 1.6e-60 203.7 3.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit GIT_SHD PF08518.6 KOS20061.1 - 0.047 13.0 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT BUD22 PF09073.5 KOS20063.1 - 1.4e-54 185.8 68.2 1.2e-50 172.9 47.3 3.0 1 1 0 1 1 1 1 BUD22 MIP-T3 PF10243.4 KOS20063.1 - 2 6.8 40.1 1.1 7.6 14.7 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Sporozoite_P67 PF05642.6 KOS20063.1 - 2.4 5.9 22.7 1.4 6.7 4.9 2.6 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Suf PF05843.9 KOS20063.1 - 8.6 5.9 14.3 3.3 7.3 2.6 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Nop53 PF07767.6 KOS20063.1 - 9 5.1 33.0 0.068 12.1 7.8 3.2 3 0 0 3 3 3 0 Nop53 (60S ribosomal biogenesis) Rad4 PF03835.10 KOS20065.1 - 2.7e-28 98.1 0.0 7.2e-28 96.8 0.0 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KOS20065.1 - 8.9e-25 86.2 0.2 1.5e-24 85.4 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KOS20065.1 - 3.2e-22 77.7 0.0 6e-22 76.9 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KOS20065.1 - 6.1e-12 45.6 1.7 1e-10 41.7 0.1 3.7 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KOS20065.1 - 1.2e-05 25.4 0.3 0.00051 20.2 0.2 2.6 1 1 0 1 1 1 1 Transglutaminase-like superfamily Mito_carr PF00153.22 KOS20066.1 - 2.8e-53 177.5 4.9 2.6e-18 65.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ABC1 PF03109.11 KOS20067.1 - 1.8e-25 89.2 0.0 3.3e-16 59.3 0.0 2.5 2 0 0 2 2 2 2 ABC1 family TCO89 PF10452.4 KOS20068.1 - 1e-05 24.6 14.3 0.0055 15.6 0.0 3.3 3 0 0 3 3 3 2 TORC1 subunit TCO89 RRM_5 PF13893.1 KOS20069.1 - 0.00084 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 KOS20069.1 - 0.0062 16.1 0.1 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 DbpA RNA binding domain Cyto_heme_lyase PF01265.12 KOS20070.1 - 9e-74 248.3 0.0 1.1e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase PseudoU_synth_2 PF00849.17 KOS20071.1 - 1.4e-28 99.7 0.4 2.2e-28 99.1 0.0 1.5 2 0 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.20 KOS20071.1 - 0.0014 17.9 0.0 0.0014 17.9 0.0 2.0 3 0 0 3 3 3 1 S4 domain Na_Ca_ex PF01699.19 KOS20072.1 - 5.9e-50 168.5 30.2 1.3e-25 89.6 8.2 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Glyco_hydro_81 PF03639.8 KOS20073.1 - 2.1e-48 164.9 0.2 2.3e-48 164.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 MmlI PF09448.5 KOS20073.1 - 0.062 13.0 0.3 0.17 11.6 0.1 1.7 1 1 1 2 2 2 0 Methylmuconolactone methyl-isomerase PTCB-BRCT PF12738.2 KOS20074.1 - 0.00021 21.0 0.2 0.00052 19.8 0.1 1.8 1 1 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KOS20074.1 - 0.0034 17.4 0.0 0.0065 16.5 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3474 PF11960.3 KOS20074.1 - 0.03 14.3 1.0 0.03 14.3 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Sdh5 PF03937.11 KOS20075.1 - 2.8e-24 84.5 0.0 5.7e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase ADH_zinc_N PF00107.21 KOS20076.1 - 1.2e-27 95.9 0.3 1.6e-27 95.6 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KOS20076.1 - 1.8e-17 64.4 0.1 4.9e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DapB_N PF01113.15 KOS20076.1 - 0.027 14.4 0.1 0.13 12.2 0.0 2.0 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Rep_fac-A_C PF08646.5 KOS20078.1 - 1.9e-50 170.3 6.4 8.5e-49 165.0 2.9 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KOS20078.1 - 3.2e-24 84.6 0.1 1.7e-23 82.2 0.0 2.1 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KOS20078.1 - 6.4e-17 61.1 1.5 1.5e-12 47.1 0.0 3.5 2 1 1 3 3 3 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 KOS20078.1 - 0.029 14.4 0.0 0.097 12.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF223 zf-U1 PF06220.7 KOS20079.1 - 2.6e-22 78.0 3.4 4.4e-22 77.3 2.3 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 KOS20079.1 - 0.016 15.2 3.8 0.047 13.8 2.6 1.7 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding MIS13 PF08202.6 KOS20081.1 - 1.1e-54 185.5 2.1 4.3e-54 183.6 0.0 2.4 2 0 0 2 2 2 1 Mis12-Mtw1 protein family EMP24_GP25L PF01105.19 KOS20082.1 - 8.3e-41 139.7 0.0 9.7e-41 139.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Helicase_RecD PF05127.9 KOS20082.1 - 0.14 11.7 0.0 0.4 10.3 0.0 1.6 1 1 1 2 2 2 0 Helicase Transaldolase PF00923.14 KOS20083.1 - 1.8e-24 86.3 0.0 2.3e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Transaldolase PDT PF00800.13 KOS20083.1 - 0.14 11.7 2.0 1.3 8.5 0.1 2.6 2 1 1 3 3 3 0 Prephenate dehydratase GCFC PF07842.7 KOS20084.1 - 2.7e-64 217.1 8.2 4e-64 216.6 5.7 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KOS20084.1 - 2.9e-14 52.5 1.5 2.9e-14 52.5 1.0 2.4 2 0 0 2 2 2 1 G-patch domain TIP_N PF12457.3 KOS20084.1 - 7.4e-10 38.8 24.4 8.4e-10 38.6 10.8 3.4 2 1 1 3 3 3 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 KOS20084.1 - 2.6e-09 36.8 1.8 1e-08 34.8 0.1 2.7 2 0 0 2 2 2 1 DExH-box splicing factor binding site ATP-synt_E PF05680.7 KOS20084.1 - 0.21 11.5 2.4 0.6 10.1 1.6 1.7 1 0 0 1 1 1 0 ATP synthase E chain DUF3429 PF11911.3 KOS20085.1 - 2.1e-41 141.1 4.0 2.7e-41 140.8 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Methyltransf_4 PF02390.12 KOS20085.1 - 0.071 12.1 2.9 0.11 11.5 2.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Peptidase_S49_N PF08496.5 KOS20085.1 - 0.14 11.9 2.1 0.25 11.1 1.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NARP1 PF12569.3 KOS20085.1 - 1.4 7.6 11.0 2 7.0 7.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-CCHC PF00098.18 KOS20086.1 - 7.6e-05 22.4 10.5 0.012 15.5 0.2 2.9 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.1 KOS20086.1 - 0.73 9.5 17.6 0.76 9.4 0.5 3.8 4 0 0 4 4 4 0 Zinc knuckle RRM_1 PF00076.17 KOS20087.1 - 4.9e-18 64.5 0.1 4.6e-12 45.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS20087.1 - 2.4e-16 59.4 0.0 3e-08 33.5 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS20087.1 - 0.0058 16.4 0.1 2.9 7.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 KOS20087.1 - 5.2 4.9 18.9 2.1 6.2 7.5 2.4 2 0 0 2 2 2 0 CDC45-like protein SUR7 PF06687.7 KOS20088.1 - 3.6e-19 69.1 6.8 3.6e-19 69.1 4.7 1.4 1 1 0 1 1 1 1 SUR7/PalI family ORMDL PF04061.9 KOS20089.1 - 2.8e-60 201.7 5.6 3.3e-60 201.5 3.9 1.1 1 0 0 1 1 1 1 ORMDL family PIG-P PF08510.7 KOS20089.1 - 0.022 14.3 2.3 0.042 13.4 1.6 1.4 1 0 0 1 1 1 0 PIG-P Med1 PF10744.4 KOS20090.1 - 3.8e-35 121.3 0.0 1.8e-34 119.1 0.0 2.0 2 1 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 MFS_1 PF07690.11 KOS20092.1 - 1.7e-31 109.1 60.8 1.6e-27 96.1 26.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS20092.1 - 4.2e-22 78.3 23.7 2.4e-16 59.3 4.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter zf-PHD-like PF15446.1 KOS20093.1 - 8.2e-66 220.5 19.2 1.6e-65 219.6 13.3 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 KOS20093.1 - 2.1e-57 194.2 0.2 2.9e-57 193.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS20093.1 - 1.2e-13 50.6 0.0 1.4e-12 47.3 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KOS20093.1 - 1e-10 40.9 0.7 2.6e-10 39.6 0.5 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 KOS20093.1 - 6.2e-08 32.1 0.3 5.3e-06 26.0 0.5 2.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 KOS20093.1 - 8.1e-06 25.4 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.24 KOS20093.1 - 2.1e-05 24.1 8.7 2.1e-05 24.1 6.1 3.9 2 2 2 4 4 3 1 PHD-finger Prok-RING_1 PF14446.1 KOS20093.1 - 0.0031 17.1 3.5 0.0031 17.1 2.4 3.1 3 1 1 4 4 4 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KOS20093.1 - 0.0054 16.0 4.6 0.0054 16.0 3.2 3.9 4 1 0 4 4 4 1 PHD-finger SpoU_methylase PF00588.14 KOS20095.1 - 3.1e-21 75.7 0.0 5.2e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 KOS20095.1 - 1.3e-08 34.9 0.0 2.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding HET PF06985.6 KOS20096.1 - 1.9e-10 41.0 0.0 3.3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RNA_Me_trans PF04252.8 KOS20097.1 - 7.2e-30 103.8 0.0 1.9e-16 60.0 0.0 2.0 1 1 1 2 2 2 2 Predicted SAM-dependent RNA methyltransferase DLH PF01738.13 KOS20098.1 - 4.3e-18 65.3 0.1 1.8e-16 60.1 0.1 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KOS20098.1 - 1.6e-08 34.4 0.3 2.2e-08 33.9 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family HMG-CoA_red PF00368.13 KOS20099.1 - 2.2e-28 99.0 1.8 2.6e-28 98.7 1.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase YjbE PF11106.3 KOS20099.1 - 5.1 7.1 12.5 10 6.2 8.7 1.7 1 1 0 1 1 1 0 Exopolysaccharide production protein YjbE Herpes_capsid PF06112.6 KOS20099.1 - 8.7 6.3 11.3 13 5.8 7.8 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Isochorismatase PF00857.15 KOS20100.1 - 5.8e-23 81.6 0.1 5.4e-22 78.5 0.1 1.9 1 1 0 1 1 1 1 Isochorismatase family DUF221 PF02714.10 KOS20101.1 - 1.4e-56 191.7 16.9 3.9e-44 150.8 8.7 3.1 1 1 1 2 2 2 2 Domain of unknown function DUF221 DUF3779 PF12621.3 KOS20101.1 - 2.7e-23 81.6 0.1 6.6e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein Aminotran_5 PF00266.14 KOS20102.1 - 2.5e-11 42.9 0.0 4.2e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KOS20102.1 - 0.0034 16.4 0.0 0.0052 15.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Thioredoxin PF00085.15 KOS20103.1 - 7.7e-30 102.6 0.0 1.6e-24 85.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KOS20103.1 - 5.3e-09 36.2 0.1 0.00082 19.5 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KOS20103.1 - 4.9e-06 26.5 0.0 0.0087 16.1 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KOS20103.1 - 0.0049 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Calsequestrin PF01216.12 KOS20103.1 - 0.031 13.0 0.0 0.079 11.7 0.0 1.7 2 0 0 2 2 2 0 Calsequestrin RNase_PH PF01138.16 KOS20104.1 - 1.1e-34 119.5 0.1 1.9e-34 118.8 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 2OG-FeII_Oxy PF03171.15 KOS20105.1 - 1.1e-21 76.8 0.0 3.9e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KOS20105.1 - 9.5e-13 48.6 0.0 2.5e-12 47.3 0.0 1.6 1 1 1 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal IDO PF01231.13 KOS20106.1 - 1.6e-137 458.4 0.0 2e-137 458.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 KOS20106.1 - 0.075 11.5 0.0 0.38 9.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) EVE PF01878.13 KOS20107.1 - 2.4e-50 170.2 0.0 3.9e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 EVE domain Neisseria_TspB PF05616.8 KOS20107.1 - 0.2 9.9 5.0 0.28 9.4 3.5 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Glyco_hydro_16 PF00722.16 KOS20108.1 - 4.3e-08 32.6 0.0 1.3e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Formyl_trans_N PF00551.14 KOS20109.1 - 1.4e-09 37.7 0.0 2.9e-08 33.4 0.0 2.7 1 1 1 2 2 2 1 Formyl transferase MBF1 PF08523.5 KOS20111.1 - 2.2e-23 82.0 0.9 4e-23 81.2 0.7 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KOS20111.1 - 1.3e-11 44.1 0.3 2.2e-11 43.4 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 KOS20111.1 - 9.3e-05 22.5 1.0 0.0002 21.5 0.7 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 KOS20111.1 - 0.045 13.8 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MRC1 PF09444.5 KOS20112.1 - 1e-35 123.1 15.1 1e-35 123.1 10.5 4.8 4 1 1 5 5 5 1 MRC1-like domain DUF843 PF05814.6 KOS20113.1 - 0.076 12.8 1.3 0.14 11.9 0.9 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) NAD_binding_5 PF07994.7 KOS20114.1 - 4.7e-113 377.5 0.4 5.6e-113 377.3 0.3 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KOS20114.1 - 1.2e-45 153.8 0.6 3.2e-45 152.5 0.4 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase FNIP_C PF14638.1 KOS20114.1 - 0.033 13.5 0.1 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Folliculin-interacting protein C-terminus DUF3405 PF11885.3 KOS20115.1 - 1.2e-171 571.3 6.9 1.8e-171 570.7 4.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) GATase_5 PF13507.1 KOS20116.1 - 1e-96 322.8 0.0 1.5e-96 322.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KOS20116.1 - 6.5e-37 126.8 0.4 8.4e-20 71.3 0.1 3.0 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KOS20116.1 - 0.052 13.7 0.2 3.6 7.8 0.0 3.3 2 1 1 3 3 3 0 AIR synthase related protein, N-terminal domain Pyridoxal_deC PF00282.14 KOS20117.1 - 8.7e-25 86.9 0.0 1.2e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KOS20117.1 - 0.0063 15.6 0.0 0.024 13.8 0.0 1.7 1 1 1 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KOS20117.1 - 0.037 12.7 0.0 0.14 10.8 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class-V Aminotran_1_2 PF00155.16 KOS20117.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Sulfatase PF00884.18 KOS20118.1 - 2.2e-20 73.0 0.6 3.5e-20 72.4 0.4 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KOS20118.1 - 6.2e-08 32.3 0.0 9.5e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KOS20118.1 - 0.00047 18.6 0.0 0.00071 18.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) ATG27 PF09451.5 KOS20118.1 - 0.066 12.4 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 SUR7 PF06687.7 KOS20118.1 - 0.48 9.9 9.6 4.2 6.8 7.1 2.1 2 0 0 2 2 2 0 SUR7/PalI family RseC_MucC PF04246.7 KOS20118.1 - 0.54 9.8 2.6 1.6 8.3 1.8 1.7 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC TPR_12 PF13424.1 KOS20119.1 - 2e-09 37.2 1.4 0.018 14.9 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KOS20119.1 - 2e-08 33.7 5.5 0.0079 15.8 0.1 3.6 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 KOS20119.1 - 0.00015 21.1 1.7 3.5 7.3 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KOS20119.1 - 0.0027 17.5 3.2 3.4 7.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS20119.1 - 0.018 14.7 0.6 4.5 7.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KOS20119.1 - 0.06 13.4 0.4 0.82 9.8 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Cut8_C PF08559.5 KOS20120.1 - 3e-45 153.5 0.0 3.6e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Cut8 six-helix bundle Rad52_Rad22 PF04098.10 KOS20121.1 - 3.1e-59 199.1 0.0 4.3e-59 198.6 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF2985 PF11204.3 KOS20123.1 - 8.6e-29 99.1 3.5 2.1e-27 94.7 3.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Sulfate_transp PF00916.15 KOS20124.1 - 2.1e-77 259.8 7.8 2.1e-77 259.8 5.4 1.6 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KOS20124.1 - 2.1e-32 110.6 3.3 2.1e-32 110.6 2.3 3.5 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KOS20124.1 - 3.5e-10 39.3 0.0 6.9e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF3439 PF11921.3 KOS20124.1 - 0.12 12.0 12.0 0.38 10.5 8.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 KOS20124.1 - 0.29 8.8 3.7 0.42 8.3 2.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SNN_transmemb PF09049.5 KOS20124.1 - 1.3 8.8 7.4 0.13 11.9 0.6 3.0 3 0 0 3 3 3 0 Stannin transmembrane Mucin PF01456.12 KOS20124.1 - 1.3 8.7 18.8 0.067 12.9 9.1 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein MFS_1 PF07690.11 KOS20125.1 - 7.9e-28 97.1 27.1 7.9e-28 97.1 18.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M1 PF01433.15 KOS20126.1 - 8.9e-70 235.7 0.0 1.2e-69 235.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KOS20126.1 - 1.8e-44 150.7 0.2 3.4e-44 149.9 0.1 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KOS20126.1 - 1.8e-18 66.8 0.3 3.3e-18 65.9 0.2 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF1974 PF09317.6 KOS20126.1 - 0.072 12.4 0.0 4.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1974) Peptidase_M61 PF05299.7 KOS20126.1 - 0.27 11.2 2.6 1.3 9.0 1.8 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DUF952 PF06108.7 KOS20127.1 - 1.4e-21 76.1 0.0 1.8e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Ten1 PF12658.2 KOS20128.1 - 4.8e-32 110.3 0.0 5.5e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Kinesin PF00225.18 KOS20129.1 - 4.7e-112 373.9 0.0 8.6e-112 373.1 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 KOS20129.1 - 4.3e-45 152.8 0.1 1e-44 151.6 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein KIF1B PF12423.3 KOS20129.1 - 1e-05 25.4 0.3 2.7e-05 24.0 0.2 1.8 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 KOS20129.1 - 4.3e-05 23.5 0.0 0.00032 20.7 0.1 2.4 2 0 0 2 2 2 1 FHA domain PH PF00169.24 KOS20129.1 - 0.0016 18.5 0.0 0.0079 16.3 0.0 2.3 2 0 0 2 2 2 1 PH domain AAA_22 PF13401.1 KOS20129.1 - 0.084 13.0 0.8 0.54 10.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain Methyltransf_23 PF13489.1 KOS20130.1 - 1.8e-11 43.9 0.0 3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS20130.1 - 3.2e-07 30.9 0.0 1.2e-05 25.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS20130.1 - 1.5e-06 28.6 0.0 7.2e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS20130.1 - 0.00034 20.2 0.0 0.0046 16.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS20130.1 - 0.0056 17.1 0.0 0.014 15.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 KOS20130.1 - 0.0078 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KOS20130.1 - 0.038 13.0 0.0 0.092 11.8 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Peptidase_M48 PF01435.13 KOS20131.1 - 2.6e-39 135.1 0.0 3.9e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 RskA PF10099.4 KOS20131.1 - 0.007 16.1 2.4 0.016 14.9 1.7 1.6 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Spexin PF15171.1 KOS20131.1 - 0.026 14.4 0.3 11 6.0 0.0 2.9 3 1 0 3 3 3 0 Neuropeptide secretory protein family, NPQ, spexin SIS PF01380.17 KOS20132.1 - 2.5e-54 182.3 0.1 4.7e-30 103.8 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KOS20132.1 - 1.5e-28 99.5 0.0 3.7e-19 68.6 0.0 2.3 1 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KOS20132.1 - 3.9e-19 68.9 0.0 9.4e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KOS20132.1 - 7.5e-12 45.0 0.0 1.7e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KOS20132.1 - 1.1e-08 34.0 0.0 1.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 KOS20132.1 - 0.11 12.1 0.0 0.41 10.3 0.0 2.0 1 0 0 1 1 1 0 SIS domain AAA PF00004.24 KOS20133.1 - 5.1e-43 146.4 0.0 8.8e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KOS20133.1 - 1.1e-07 32.0 0.0 5.9e-06 26.3 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 KOS20133.1 - 1.5e-06 28.0 0.1 3.7e-05 23.4 0.0 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KOS20133.1 - 2.7e-06 27.3 0.0 7.7e-06 25.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KOS20133.1 - 2.9e-06 27.4 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 KOS20133.1 - 7.4e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KOS20133.1 - 0.00031 20.4 0.0 0.00075 19.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 KOS20133.1 - 0.00031 19.7 0.0 0.00058 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KOS20133.1 - 0.00044 21.0 1.2 0.0023 18.7 0.3 2.6 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KOS20133.1 - 0.00096 19.0 0.0 0.0027 17.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KOS20133.1 - 0.0014 18.5 0.0 0.0063 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KOS20133.1 - 0.0017 17.1 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 KOS20133.1 - 0.0018 18.5 1.1 0.0081 16.4 0.0 2.6 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 KOS20133.1 - 0.0023 17.3 0.0 0.0054 16.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KOS20133.1 - 0.003 16.7 0.0 0.0062 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 KOS20133.1 - 0.0033 17.0 0.4 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KOS20133.1 - 0.0048 17.0 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 KOS20133.1 - 0.0052 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 KOS20133.1 - 0.0077 15.8 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KOS20133.1 - 0.0077 15.7 0.0 0.025 14.0 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 KOS20133.1 - 0.0085 15.5 0.1 0.047 13.0 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.1 KOS20133.1 - 0.013 15.8 1.5 3.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KOS20133.1 - 0.018 14.6 0.1 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KOS20133.1 - 0.02 14.1 0.1 0.056 12.6 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.1 KOS20133.1 - 0.021 14.7 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KOS20133.1 - 0.023 14.7 0.0 0.064 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF4200 PF13863.1 KOS20133.1 - 0.023 14.6 2.4 0.023 14.6 1.7 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) ResIII PF04851.10 KOS20133.1 - 0.027 14.2 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 KOS20133.1 - 0.03 14.0 0.1 0.14 11.8 0.0 2.1 2 1 0 2 2 1 0 Archaeal ATPase KaiC PF06745.8 KOS20133.1 - 0.03 13.4 0.4 0.11 11.5 0.0 2.2 3 0 0 3 3 3 0 KaiC NACHT PF05729.7 KOS20133.1 - 0.041 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 KOS20133.1 - 0.044 13.3 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KOS20133.1 - 0.086 12.4 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain eIF-1a PF01176.14 KOS20133.1 - 0.089 12.2 0.1 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Parvo_NS1 PF01057.12 KOS20133.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DivIC PF04977.10 KOS20133.1 - 0.56 9.7 3.3 3.7 7.0 1.0 2.6 2 0 0 2 2 2 0 Septum formation initiator Mago-bind PF09282.5 KOS20134.1 - 8.3e-15 54.0 2.9 1.6e-14 53.1 2.0 1.5 1 0 0 1 1 1 1 Mago binding AUX_IAA PF02309.11 KOS20134.1 - 0.0059 16.3 8.0 0.0083 15.8 5.6 1.2 1 0 0 1 1 1 1 AUX/IAA family RR_TM4-6 PF06459.7 KOS20134.1 - 0.33 10.7 14.8 0.46 10.3 10.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 KOS20134.1 - 0.36 8.4 7.0 0.37 8.4 4.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.10 KOS20134.1 - 0.68 8.4 6.6 0.86 8.1 4.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.12 KOS20134.1 - 0.7 9.6 10.3 1 9.1 7.1 1.2 1 0 0 1 1 1 0 DDHD domain Mem_trans PF03547.13 KOS20134.1 - 1.1 7.5 4.7 1.3 7.2 3.2 1.1 1 0 0 1 1 1 0 Membrane transport protein Zip PF02535.17 KOS20134.1 - 1.6 7.6 4.6 1.9 7.4 3.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_viral_N PF00242.12 KOS20134.1 - 2.5 7.0 8.8 3.3 6.6 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Paramyxo_ncap PF00973.14 KOS20134.1 - 3.8 6.1 9.5 4.7 5.7 6.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1510 PF07423.6 KOS20134.1 - 4 6.7 20.1 7.3 5.8 13.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 KOS20134.1 - 4.7 4.8 12.3 5.5 4.5 8.5 1.0 1 0 0 1 1 1 0 Ycf1 SRP-alpha_N PF04086.8 KOS20134.1 - 5 6.4 20.4 7.7 5.8 14.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.9 KOS20134.1 - 5.1 5.0 14.9 6.2 4.7 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein ARD PF03079.9 KOS20134.1 - 5.1 7.0 8.1 5.2 7.0 5.0 1.5 1 1 0 1 1 1 0 ARD/ARD' family DDRGK PF09756.4 KOS20134.1 - 5.8 6.2 20.4 8.8 5.6 14.2 1.3 1 0 0 1 1 1 0 DDRGK domain Neur_chan_memb PF02932.11 KOS20134.1 - 6.3 6.6 6.6 7.8 6.3 4.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.12 KOS20134.1 - 7.7 5.2 9.5 9.9 4.8 6.6 1.1 1 0 0 1 1 1 0 Presenilin MRL1 PF13003.2 KOS20134.1 - 8.1 6.2 7.3 1.3e+02 2.3 5.1 2.2 1 1 0 1 1 1 0 Ribosomal protein L1 E1-E2_ATPase PF00122.15 KOS20135.1 - 3.5e-60 202.8 1.2 6.6e-60 202.0 0.8 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KOS20135.1 - 2.8e-46 157.3 1.5 2.8e-46 157.3 1.1 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KOS20135.1 - 2.1e-25 90.4 0.3 6.7e-19 69.1 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS20135.1 - 1.5e-19 69.7 0.0 4.2e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KOS20135.1 - 5.6e-13 49.4 0.0 2e-12 47.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KOS20135.1 - 1.9e-09 36.8 0.2 7.1e-09 35.0 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KOS20135.1 - 0.00056 19.5 0.2 0.0011 18.5 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 KOS20135.1 - 0.12 12.2 2.9 0.21 11.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) DUF2976 PF11190.3 KOS20135.1 - 0.37 10.3 5.5 1.1 8.7 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) zf-UBR PF02207.15 KOS20136.1 - 6.8e-17 60.9 17.4 1.8e-16 59.5 12.1 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 KOS20136.1 - 4.5e-07 29.5 0.0 1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS CRC_subunit PF08624.5 KOS20137.1 - 5.8e-58 194.7 0.0 1.1e-57 193.8 0.0 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Cyclin PF08613.6 KOS20138.1 - 7.3e-14 52.4 0.0 1.7e-13 51.2 0.0 1.6 2 0 0 2 2 2 1 Cyclin Nefa_Nip30_N PF10187.4 KOS20139.1 - 7.4e-23 80.6 12.8 7.4e-23 80.6 8.9 3.2 2 2 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2413 PF10310.4 KOS20139.1 - 1.7 7.3 17.4 2.7 6.7 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Tim54 PF11711.3 KOS20140.1 - 4.5e-120 400.7 0.1 5.3e-120 400.5 0.0 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 MRVI1 PF05781.7 KOS20140.1 - 2.1 6.6 4.7 2.9 6.1 3.3 1.1 1 0 0 1 1 1 0 MRVI1 protein Pkinase PF00069.20 KOS20141.1 - 3.2e-55 187.1 0.0 5.6e-39 133.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KOS20141.1 - 2.4e-26 92.3 0.1 3.4e-20 72.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KOS20141.1 - 8.9e-05 21.5 0.3 0.00018 20.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KOS20141.1 - 9.1e-05 22.3 0.3 0.011 15.5 0.2 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KOS20141.1 - 0.00046 19.3 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KOS20141.1 - 0.041 12.6 0.1 0.064 12.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 KOS20141.1 - 0.075 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KOS20141.1 - 0.11 11.8 1.7 0.41 9.9 0.0 2.1 2 0 0 2 2 2 0 RIO1 family DUF605 PF04652.11 KOS20142.1 - 7.6e-88 295.4 5.6 9e-88 295.2 3.9 1.1 1 0 0 1 1 1 1 Vta1 like PAT1 PF09770.4 KOS20142.1 - 0.13 10.4 13.6 0.14 10.3 9.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OPT PF03169.10 KOS20143.1 - 1.2e-167 559.1 49.0 1.3e-167 558.9 34.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SAPS PF04499.10 KOS20144.1 - 1.5e-35 122.8 0.5 2.3e-35 122.1 0.0 1.5 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Nucleoplasmin PF03066.10 KOS20144.1 - 0.28 10.6 3.7 0.49 9.9 2.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 KOS20144.1 - 0.37 10.0 1.2 1.8 7.7 1.4 1.6 2 0 0 2 2 2 0 NOA36 protein Nop14 PF04147.7 KOS20145.1 - 0.53 8.1 19.6 0.61 7.9 13.6 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KOS20145.1 - 8.5 4.2 7.0 8.8 4.2 4.8 1.3 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 KOS20146.1 - 3.9e-118 395.0 0.0 2.3e-117 392.5 0.0 1.9 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein HEAT_2 PF13646.1 KOS20147.1 - 6.4e-06 26.3 1.4 0.026 14.7 0.0 4.2 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.17 KOS20147.1 - 4.9e-05 23.0 0.3 1.4 9.1 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat CLASP_N PF12348.3 KOS20147.1 - 0.00034 20.0 0.0 0.003 16.9 0.0 2.4 3 0 0 3 3 3 1 CLASP N terminal TBPIP PF07106.8 KOS20147.1 - 0.028 13.9 2.1 0.089 12.3 1.5 1.8 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ACT_6 PF13740.1 KOS20147.1 - 0.049 13.3 0.1 4.8 6.9 0.0 2.8 3 0 0 3 3 3 0 ACT domain HEAT_EZ PF13513.1 KOS20147.1 - 0.066 13.7 1.6 23 5.6 0.0 4.3 2 2 3 5 5 5 0 HEAT-like repeat DUF21 PF01595.15 KOS20147.1 - 0.29 10.4 2.2 0.17 11.1 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF21 GrpE PF01025.14 KOS20147.1 - 4.4 6.8 9.1 8.9 5.8 0.3 3.1 3 0 0 3 3 3 0 GrpE DUF1162 PF06650.7 KOS20148.1 - 4.8e-88 294.9 0.0 2.1e-87 292.8 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1162) ATG_C PF09333.6 KOS20148.1 - 1.6e-05 24.9 0.0 8.7e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 ATG C terminal domain Chorein_N PF12624.2 KOS20149.1 - 2.2e-42 143.2 0.1 7e-42 141.7 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter NUC129 PF08157.6 KOS20149.1 - 0.073 12.9 1.3 0.29 11.0 0.3 2.4 2 0 0 2 2 2 0 NUC129 domain DUF647 PF04884.9 KOS20150.1 - 1.2e-74 250.7 1.2 1.4e-74 250.4 0.8 1.0 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF4117 PF13491.1 KOS20150.1 - 0.0017 17.8 0.9 0.0037 16.7 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4117) GHMP_kinases_N PF00288.21 KOS20151.1 - 1.1e-09 38.1 1.2 3e-09 36.8 0.9 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Acetyltransf_8 PF13523.1 KOS20152.1 - 6e-21 74.9 0.0 1.3e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CDC45 PF02724.9 KOS20152.1 - 0.0008 17.5 1.1 0.001 17.2 0.8 1.1 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.8 KOS20152.1 - 0.023 14.2 2.8 0.031 13.8 1.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 KOS20152.1 - 0.094 10.6 5.4 0.12 10.2 3.8 1.1 1 0 0 1 1 1 0 Nop14-like family ANAPC15 PF15243.1 KOS20152.1 - 0.14 12.1 4.3 0.28 11.2 3.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF3499 PF12005.3 KOS20152.1 - 0.73 10.0 5.5 1.6 8.9 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3499) Nucleoplasmin PF03066.10 KOS20152.1 - 1.6 8.2 6.5 2.5 7.6 4.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 KOS20152.1 - 4.7 6.7 9.4 7.1 6.1 6.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Cyto_heme_lyase PF01265.12 KOS20153.1 - 6.9e-58 196.2 0.1 7.7e-58 196.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase A_deaminase PF00962.17 KOS20154.1 - 2.8e-41 141.5 0.0 8.4e-40 136.6 0.0 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase Acyl-CoA_dh_1 PF00441.19 KOS20155.1 - 3.9e-14 53.0 0.1 7.1e-09 35.9 0.0 2.6 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KOS20155.1 - 1.5e-06 27.5 0.7 6.3e-05 22.4 0.3 3.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Hydantoinase_B PF02538.9 KOS20156.1 - 3.2e-196 652.6 0.0 6.7e-195 648.2 0.0 2.1 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KOS20156.1 - 2.6e-93 312.2 0.5 4.8e-93 311.4 0.4 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KOS20156.1 - 1.1e-58 197.6 1.0 6.6e-57 191.8 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region NmrA PF05368.8 KOS20157.1 - 8.8e-06 25.1 0.0 9.7e-05 21.7 0.0 2.3 3 0 0 3 3 3 1 NmrA-like family NAD_binding_10 PF13460.1 KOS20157.1 - 1.4e-05 25.1 0.2 3.1e-05 24.0 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KOS20157.1 - 0.0046 15.6 0.0 0.0062 15.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KOS20157.1 - 0.012 15.5 0.9 0.031 14.1 0.1 2.1 2 0 0 2 2 2 0 short chain dehydrogenase TrkA_N PF02254.13 KOS20157.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 KOS20157.1 - 0.083 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase MARVEL PF01284.18 KOS20158.1 - 1.1e-16 60.9 9.7 1.4e-16 60.5 6.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF3816 PF12822.2 KOS20158.1 - 0.066 13.0 2.4 0.081 12.8 1.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) 5TM-5TMR_LYT PF07694.7 KOS20158.1 - 0.095 12.0 2.6 0.15 11.3 1.8 1.3 1 0 0 1 1 1 0 5TMR of 5TMR-LYT LRRNT_2 PF08263.7 KOS20158.1 - 2.1 8.3 6.9 3.5 7.6 0.6 3.1 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain APG5 PF04106.7 KOS20160.1 - 4.6e-39 133.9 0.0 1.2e-38 132.5 0.0 1.7 1 1 0 1 1 1 1 Autophagy protein Apg5 RNase_H2_suC PF08615.6 KOS20162.1 - 0.078 12.8 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Daxx PF03344.10 KOS20162.1 - 0.15 10.5 6.9 0.2 10.1 4.8 1.1 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 KOS20162.1 - 0.29 10.6 14.9 0.44 10.0 10.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 KOS20162.1 - 0.3 9.0 5.6 0.39 8.6 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KOS20162.1 - 0.32 8.8 8.1 0.4 8.5 5.6 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 KOS20162.1 - 0.42 9.2 14.5 0.042 12.5 6.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Paf1 PF03985.8 KOS20162.1 - 1.1 7.9 5.8 1.4 7.6 4.0 1.1 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.7 KOS20162.1 - 1.4 8.0 8.7 2 7.5 6.1 1.1 1 0 0 1 1 1 0 NOA36 protein YL1 PF05764.8 KOS20162.1 - 1.5 8.3 9.5 0.23 11.0 4.0 1.5 2 0 0 2 2 2 0 YL1 nuclear protein CENP-B_dimeris PF09026.5 KOS20162.1 - 1.6 9.0 13.9 3 8.1 9.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain VID27 PF08553.5 KOS20162.1 - 8.4 4.4 8.2 11 4.0 5.7 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein WD40 PF00400.27 KOS20163.1 - 1.4e-32 110.3 9.6 2.9e-08 33.2 0.2 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KOS20163.1 - 0.035 12.8 0.0 4.4 5.9 0.0 2.8 1 1 2 3 3 3 0 Nup133 N terminal like eIF2A PF08662.6 KOS20163.1 - 0.23 11.1 0.0 12 5.5 0.0 2.5 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A UQ_con PF00179.21 KOS20164.1 - 1.6e-48 163.7 0.0 1.7e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS20164.1 - 3.6e-05 23.5 0.0 4.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KOS20164.1 - 0.037 13.9 0.9 0.072 12.9 0.6 1.8 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.16 KOS20165.1 - 2.1e-67 227.3 0.0 3.1e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KOS20165.1 - 2.3e-36 124.2 0.0 3.8e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KOS20165.1 - 1.7e-28 99.2 0.0 3.9e-28 98.0 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KOS20165.1 - 2.6e-08 33.3 0.0 4.7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 KOS20165.1 - 0.00011 21.0 0.0 0.0031 16.2 0.0 2.5 1 1 2 3 3 3 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 KOS20165.1 - 0.00072 18.5 0.0 0.0029 16.5 0.0 1.8 2 0 0 2 2 2 1 NAD synthase DUF836 PF05768.9 KOS20166.1 - 2.2e-12 47.0 0.0 2.5e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 KOS20166.1 - 0.0021 18.0 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 KOS20166.1 - 0.013 15.6 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain HpcH_HpaI PF03328.9 KOS20167.1 - 3.2e-28 98.1 0.0 2.4e-23 82.1 0.0 2.1 1 1 1 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family SHS2_Rpb7-N PF03876.12 KOS20168.1 - 2.5e-15 56.3 0.0 3.9e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KOS20168.1 - 1.6e-13 50.5 0.0 2.3e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.6 KOS20169.1 - 7.8e-17 60.9 0.0 1.2e-16 60.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) ABC2_membrane_2 PF12679.2 KOS20169.1 - 0.055 12.3 5.1 0.061 12.1 3.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3852 PF12963.2 KOS20169.1 - 0.71 9.9 5.9 0.056 13.4 0.7 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3852) MreD PF04093.7 KOS20169.1 - 8 6.2 7.6 1 9.1 0.7 2.4 2 1 1 3 3 3 0 rod shape-determining protein MreD Porin_3 PF01459.17 KOS20170.1 - 1e-62 211.9 3.8 1.1e-62 211.7 2.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin DnaJ PF00226.26 KOS20171.1 - 6.6e-18 64.2 0.1 6.6e-18 64.2 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain Glyco_hydro_47 PF01532.15 KOS20172.1 - 1.3e-155 518.4 0.0 1.5e-155 518.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CHORD PF04968.7 KOS20173.1 - 5.3e-52 173.9 14.4 7.7e-26 90.1 3.2 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 KOS20173.1 - 1.1e-12 48.3 0.1 1.7e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 CS domain DUF1253 PF06862.7 KOS20174.1 - 6.6e-161 535.6 0.0 1e-160 534.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Plasmodium_Vir PF05795.6 KOS20174.1 - 0.42 9.7 4.9 0.75 8.9 3.4 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein JAB PF01398.16 KOS20175.1 - 1.4e-16 60.2 0.0 2.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KOS20175.1 - 1.9e-12 47.2 0.0 3.4e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function SUZ PF12752.2 KOS20176.1 - 1.8e-07 31.5 1.4 1.8e-07 31.5 1.0 2.5 2 0 0 2 2 2 1 SUZ domain zf-CCHC_3 PF13917.1 KOS20177.1 - 1.3e-11 44.0 1.6 1.9e-11 43.4 1.1 1.3 1 0 0 1 1 1 1 Zinc knuckle cwf18 PF08315.7 KOS20178.1 - 1.1e-42 145.6 2.0 1.1e-42 145.6 1.4 2.3 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor BSP_II PF05432.6 KOS20178.1 - 0.44 9.7 12.2 0.95 8.6 8.5 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Mucin PF01456.12 KOS20178.1 - 0.57 9.9 18.9 1.5 8.5 13.1 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1676 PF07898.8 KOS20178.1 - 1.8 8.8 5.8 0.34 11.2 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1676) DUF3439 PF11921.3 KOS20178.1 - 2.4 7.9 11.3 3.7 7.3 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PPR_2 PF13041.1 KOS20179.1 - 3.2e-15 55.8 0.0 8.8e-06 25.6 0.0 6.1 5 2 2 7 7 7 3 PPR repeat family PPR_1 PF12854.2 KOS20179.1 - 1.8e-09 36.8 0.0 0.014 14.8 0.0 4.7 5 0 0 5 5 5 3 PPR repeat PPR PF01535.15 KOS20179.1 - 6.4e-07 28.9 0.0 0.26 11.3 0.0 4.8 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.1 KOS20179.1 - 6.2e-06 26.0 6.8 0.051 13.8 0.0 5.9 6 0 0 6 6 6 2 Pentatricopeptide repeat domain Ank_4 PF13637.1 KOS20179.1 - 0.1 13.1 0.0 32 5.1 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) NAAA-beta PF15508.1 KOS20179.1 - 0.15 12.4 0.0 0.5 10.7 0.0 1.9 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Hexapep_2 PF14602.1 KOS20180.1 - 6.1e-13 48.0 19.6 9.2e-07 28.3 2.7 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 KOS20180.1 - 9.1e-12 43.9 20.6 5.6e-07 28.7 2.4 3.3 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 KOS20180.1 - 5e-09 36.0 0.0 1.3e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.13 KOS20180.1 - 0.0044 16.9 5.8 0.01 15.7 4.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_11 PF13720.1 KOS20180.1 - 0.026 14.7 0.1 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 EMP24_GP25L PF01105.19 KOS20182.1 - 1.5e-51 174.7 0.0 1.6e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.20 KOS20183.1 - 8.8e-36 123.3 0.0 1.1e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS20183.1 - 1.8e-14 53.4 0.0 2.4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS20183.1 - 0.0092 15.7 0.0 0.41 10.3 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family UQ_con PF00179.21 KOS20185.1 - 8.8e-37 125.6 0.2 7.6e-22 77.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS20185.1 - 6.1e-05 22.7 0.0 0.023 14.4 0.0 2.3 2 0 0 2 2 2 2 Prokaryotic E2 family B RWD PF05773.17 KOS20185.1 - 0.018 14.9 0.0 0.35 10.7 0.0 2.3 1 1 1 2 2 2 0 RWD domain HMG_box PF00505.14 KOS20187.1 - 8.7e-10 38.7 2.3 1.3e-08 34.9 0.1 4.4 3 2 1 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KOS20187.1 - 1e-05 25.8 0.3 1e-05 25.8 0.2 3.5 3 2 0 3 3 3 2 HMG-box domain Flavin_Reduct PF01613.13 KOS20187.1 - 0.15 11.9 0.7 0.9 9.3 0.2 2.1 2 0 0 2 2 2 0 Flavin reductase like domain Imm35 PF15581.1 KOS20187.1 - 0.22 11.5 0.1 0.22 11.5 0.1 2.2 2 1 0 2 2 2 0 Immunity protein 35 Med3 PF11593.3 KOS20187.1 - 0.46 9.6 7.9 0.57 9.3 5.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Transpep_BrtH PF14399.1 KOS20187.1 - 0.93 8.7 6.8 0.055 12.7 0.4 1.9 2 0 0 2 2 2 0 NlpC/p60-like transpeptidase SOBP PF15279.1 KOS20187.1 - 1.7 8.9 7.3 2.4 8.4 5.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Proteasome PF00227.21 KOS20188.1 - 3.1e-31 108.1 0.0 3.7e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF2567 PF10821.3 KOS20188.1 - 0.053 13.0 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) 3Beta_HSD PF01073.14 KOS20189.1 - 5.5e-67 225.4 0.0 7.1e-67 225.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KOS20189.1 - 1.7e-31 109.4 0.1 2.7e-31 108.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KOS20189.1 - 4.2e-17 61.9 0.1 6.6e-17 61.3 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KOS20189.1 - 5.5e-16 58.2 0.0 1.5e-13 50.2 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KOS20189.1 - 6.4e-12 45.8 0.2 8.9e-12 45.3 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KOS20189.1 - 2.9e-07 30.5 0.7 9.5e-07 28.8 0.5 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KOS20189.1 - 3.9e-06 25.9 0.3 1.9e-05 23.7 0.2 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KOS20189.1 - 0.017 14.8 0.7 0.11 12.0 0.5 2.2 1 1 0 1 1 1 0 KR domain eIF-5_eIF-2B PF01873.12 KOS20190.1 - 4.4e-45 152.3 1.1 6.5e-45 151.8 0.7 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 MYT1 PF08474.6 KOS20190.1 - 0.017 14.6 0.9 0.59 9.5 0.1 2.3 1 1 1 2 2 2 0 Myelin transcription factor 1 Lar_restr_allev PF14354.1 KOS20190.1 - 0.037 14.3 0.1 0.11 12.7 0.1 1.9 1 0 0 1 1 1 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.7 KOS20190.1 - 0.13 11.6 0.8 0.27 10.5 0.5 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding DNA_RNApol_7kD PF03604.8 KOS20190.1 - 0.37 10.3 2.7 1.3 8.5 1.9 2.0 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zf-HYPF PF07503.7 KOS20190.1 - 0.53 9.7 3.8 2.7 7.4 2.8 2.1 1 1 1 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.5 KOS20190.1 - 0.79 9.9 7.8 0.83 9.8 0.2 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain DUF4536 PF15055.1 KOS20192.1 - 0.056 13.5 4.1 0.081 13.0 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4536) Adap_comp_sub PF00928.16 KOS20193.1 - 1.4e-58 198.0 0.0 8.7e-58 195.4 0.0 1.9 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KOS20193.1 - 0.0018 17.9 0.1 0.003 17.2 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldedh PF00171.17 KOS20194.1 - 1.2e-74 251.3 0.0 1.5e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ECR1_N PF14382.1 KOS20195.1 - 3.1e-08 32.7 0.1 5.7e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KOS20195.1 - 0.0025 17.7 0.1 0.012 15.5 0.1 2.0 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 AFG1_ATPase PF03969.11 KOS20196.1 - 4.9e-47 160.4 0.0 2.3e-23 82.6 0.0 4.3 5 0 0 5 5 5 3 AFG1-like ATPase AAA_16 PF13191.1 KOS20196.1 - 8.4e-06 25.8 0.9 3.5e-05 23.8 0.6 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KOS20196.1 - 0.00016 21.7 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KOS20196.1 - 0.00033 20.4 0.0 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 KOS20196.1 - 0.0026 17.4 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 KOS20196.1 - 0.024 14.9 0.0 0.39 11.0 0.0 2.1 1 1 1 2 2 2 0 ABC transporter Bac_DnaA PF00308.13 KOS20196.1 - 0.029 13.9 0.0 7 6.2 0.0 3.0 3 0 0 3 3 3 0 Bacterial dnaA protein KAP_NTPase PF07693.9 KOS20196.1 - 0.042 12.8 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA PF00004.24 KOS20196.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 KOS20196.1 - 0.19 10.6 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Nucleoporin_N PF08801.6 KOS20197.1 - 2.2e-74 250.6 0.1 3e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 KOS20197.1 - 1.5e-71 241.6 6.2 2.2e-71 241.1 4.3 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF3594 PF12165.3 KOS20197.1 - 0.057 13.0 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3594) Acyl_transf_1 PF00698.16 KOS20198.1 - 1.6e-20 73.7 0.2 2.7e-15 56.5 0.4 2.1 1 1 1 2 2 2 2 Acyl transferase domain Sedlin_N PF04628.8 KOS20199.1 - 1.9e-17 63.3 0.0 2.2e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region SUR7 PF06687.7 KOS20201.1 - 1.1e-27 97.0 15.8 1.4e-27 96.6 11.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4064 PF13273.1 KOS20201.1 - 6.1 7.0 21.1 2.4 8.2 4.5 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) Herpes_capsid PF06112.6 KOS20202.1 - 4 7.4 7.0 7 6.6 4.8 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3433 PF11915.3 KOS20203.1 - 5.8e-47 157.8 9.2 3.6e-27 94.3 0.2 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) TRP PF06011.7 KOS20204.1 - 3.2e-147 490.6 31.9 4.1e-147 490.3 22.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KOS20204.1 - 9.7e-40 135.8 1.0 1.6e-39 135.1 0.7 1.3 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 KOS20204.1 - 0.023 14.0 0.3 0.063 12.6 0.1 1.8 1 1 0 1 1 1 0 Glycoprotein UL132 DUF1510 PF07423.6 KOS20204.1 - 0.36 10.1 0.0 0.61 9.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1240 PF06836.7 KOS20204.1 - 0.83 9.9 7.7 1.9 8.7 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) AIM24 PF01987.12 KOS20205.1 - 1e-55 188.5 0.1 1.3e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 zf-C2H2_4 PF13894.1 KOS20206.1 - 0.00053 20.1 15.5 0.45 10.9 0.5 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KOS20206.1 - 0.0011 18.9 3.2 0.014 15.5 0.8 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KOS20206.1 - 0.03 14.6 10.1 5.7 7.4 0.3 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-DBF PF07535.7 KOS20206.1 - 0.043 13.5 0.6 0.14 11.8 0.4 1.9 1 0 0 1 1 1 0 DBF zinc finger zf-TRAF PF02176.13 KOS20206.1 - 0.16 12.3 5.0 0.15 12.4 1.8 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2 PF00096.21 KOS20207.1 - 0.022 15.0 4.4 0.022 15.0 3.1 5.9 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KOS20207.1 - 0.054 13.6 0.4 0.054 13.6 0.3 3.6 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Cyt-b5 PF00173.23 KOS20208.1 - 1.4e-08 34.3 0.1 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Myb_DNA-bind_4 PF13837.1 KOS20210.1 - 0.0059 16.7 0.1 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain EBV-NA1 PF02905.9 KOS20210.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain TPR_2 PF07719.12 KOS20210.1 - 0.35 10.8 2.6 0.38 10.7 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SIS PF01380.17 KOS20211.1 - 6.4e-13 48.4 0.0 3.2e-12 46.1 0.0 2.2 2 1 0 2 2 2 1 SIS domain SIS_2 PF13580.1 KOS20211.1 - 0.0066 16.1 0.0 0.033 13.8 0.0 2.1 2 0 0 2 2 2 1 SIS domain Ceramidase_alk PF04734.8 KOS20212.1 - 7.5e-243 807.3 0.0 8.9e-243 807.0 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Peptidase_S10 PF00450.17 KOS20213.1 - 1.9e-112 376.4 0.0 2.3e-112 376.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Act-Frag_cataly PF09192.5 KOS20213.1 - 0.16 10.8 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic SPX PF03105.14 KOS20215.1 - 8.5e-18 65.1 3.7 1.6e-14 54.3 0.7 3.2 1 1 1 2 2 2 1 SPX domain bZIP_1 PF00170.16 KOS20216.1 - 7.5e-14 51.4 7.4 1e-13 51.0 5.2 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KOS20216.1 - 4.2e-08 32.8 8.7 6.4e-08 32.2 6.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KOS20216.1 - 0.00027 21.1 5.5 0.0004 20.6 3.8 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor HAP1_N PF04849.8 KOS20216.1 - 0.0025 16.8 0.8 0.0027 16.7 0.6 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region K1377 PF15352.1 KOS20216.1 - 0.0093 13.9 1.6 0.011 13.6 1.1 1.0 1 0 0 1 1 1 1 Susceptibility to monomelic amyotrophy Nnf1 PF03980.9 KOS20216.1 - 0.079 12.9 2.2 0.11 12.5 1.5 1.2 1 0 0 1 1 1 0 Nnf1 DUF3450 PF11932.3 KOS20216.1 - 0.35 10.1 4.4 0.49 9.6 3.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Atg14 PF10186.4 KOS20216.1 - 1.2 8.0 6.3 1.5 7.7 4.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GST_N_3 PF13417.1 KOS20217.1 - 7.9e-11 42.0 0.3 1.6e-10 41.0 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KOS20217.1 - 9.5e-07 28.6 0.4 2.2e-06 27.4 0.3 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KOS20217.1 - 0.00091 19.1 0.4 0.0025 17.7 0.2 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain zf-CCHC PF00098.18 KOS20218.1 - 5.4e-50 165.0 91.2 1.2e-06 28.0 2.1 10.4 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_3 PF13917.1 KOS20218.1 - 3.6e-07 29.8 77.3 0.022 14.4 0.4 10.1 2 2 8 10 10 10 8 Zinc knuckle zf-CCHC_4 PF14392.1 KOS20218.1 - 1.5e-06 27.7 69.2 0.19 11.3 1.1 10.2 9 1 1 10 10 10 10 Zinc knuckle zf-CCHC_2 PF13696.1 KOS20218.1 - 5.7e-05 22.5 5.0 0.0021 17.4 0.6 8.7 4 2 6 10 10 10 5 Zinc knuckle zf-CCHC_6 PF15288.1 KOS20218.1 - 1 9.0 78.1 0.34 10.6 0.2 10.1 7 2 3 10 10 10 0 Zinc knuckle CIAPIN1 PF05093.8 KOS20219.1 - 8.4e-36 122.0 2.4 1.5e-35 121.2 1.7 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis LIM PF00412.17 KOS20220.1 - 1.1e-18 67.0 9.9 4.5e-09 36.2 0.9 2.1 2 0 0 2 2 2 2 LIM domain WRC PF08879.5 KOS20220.1 - 0.034 13.8 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 WRC Daxx PF03344.10 KOS20221.1 - 0.049 12.1 5.2 0.048 12.1 3.6 1.0 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KOS20221.1 - 0.29 8.9 8.8 0.29 8.9 6.1 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 KOS20221.1 - 0.77 8.9 2.8 0.91 8.7 2.0 1.2 1 0 0 1 1 1 0 NOA36 protein COPI_C PF06957.6 KOS20221.1 - 2.3 6.6 7.7 2.8 6.3 5.3 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nucleoplasmin PF03066.10 KOS20221.1 - 6.8 6.1 9.3 10 5.6 6.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin Amidohydro_2 PF04909.9 KOS20223.1 - 4.7e-19 69.0 0.5 1.6e-18 67.2 0.3 1.8 1 1 0 1 1 1 1 Amidohydrolase Glyco_transf_9 PF01075.12 KOS20223.1 - 0.15 11.2 0.0 0.32 10.1 0.0 1.5 2 0 0 2 2 2 0 Glycosyltransferase family 9 (heptosyltransferase) HD PF01966.17 KOS20224.1 - 2.5e-07 30.7 1.1 2.6e-06 27.4 0.1 2.2 2 0 0 2 2 2 1 HD domain LSM PF01423.17 KOS20225.1 - 9.4e-20 69.9 0.0 1.2e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain Aldedh PF00171.17 KOS20226.1 - 6.4e-14 51.1 11.9 1e-08 34.0 5.5 2.6 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Herpes_gE PF02480.11 KOS20228.1 - 0.14 10.4 3.5 0.2 9.8 2.4 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PALP PF00291.20 KOS20229.1 - 2.3e-65 220.8 0.2 3.5e-65 220.2 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.10 KOS20229.1 - 0.13 11.8 0.2 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Kinetocho_Slk19 PF12709.2 KOS20230.1 - 2.7e-21 75.4 3.6 2.7e-21 75.4 2.5 4.7 3 1 2 5 5 5 2 Central kinetochore-associated NYD-SP28_assoc PF14775.1 KOS20230.1 - 0.018 14.6 0.5 0.061 13.0 0.4 1.9 1 0 0 1 1 1 0 Sperm tail C-terminal domain FlaC_arch PF05377.6 KOS20230.1 - 1.3 9.0 15.0 2.1 8.3 0.4 4.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) KilA-N PF04383.8 KOS20231.1 - 0.0012 18.4 0.0 0.025 14.1 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain FAD_binding_4 PF01565.18 KOS20232.1 - 3.5e-34 117.2 5.2 7e-34 116.2 3.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KOS20232.1 - 7.8e-09 35.3 0.1 1.7e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KOS20232.1 - 0.0032 16.6 0.0 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding Glyco_hydro_30 PF02055.11 KOS20233.1 - 5.8e-10 37.9 0.0 3.4e-08 32.1 0.0 2.0 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 NIF PF03031.13 KOS20234.1 - 1.6e-35 122.0 0.0 2.4e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HTH_38 PF13936.1 KOS20234.1 - 0.027 14.0 2.1 0.28 10.7 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain DUF2077 PF09850.4 KOS20234.1 - 0.071 12.5 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF2076 PF09849.4 KOS20234.1 - 2.3 8.1 10.2 2.2 8.2 0.9 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Metallophos PF00149.23 KOS20235.1 - 7e-08 32.0 5.0 8.8e-08 31.7 1.8 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Glyco_hydro_67M PF07488.7 KOS20238.1 - 1.5e-145 484.1 0.0 1.9e-145 483.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 KOS20238.1 - 2.7e-86 288.6 0.1 3.9e-86 288.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus DUF427 PF04248.7 KOS20239.1 - 4.2e-24 84.0 0.0 5.5e-12 45.1 0.0 3.2 2 1 1 3 3 3 3 Domain of unknown function (DUF427) Coatomer_E PF04733.9 KOS20240.1 - 1.5e-61 208.1 5.3 1.7e-61 207.9 3.7 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_8 PF13181.1 KOS20240.1 - 1.2e-06 27.8 1.1 0.013 15.2 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KOS20240.1 - 1.5e-06 28.2 19.1 0.00048 20.5 0.1 6.6 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 KOS20240.1 - 3.3e-06 26.4 1.2 0.0025 17.3 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KOS20240.1 - 4.2e-06 27.0 23.0 0.00034 20.8 0.5 4.6 3 1 2 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 KOS20240.1 - 3.6e-05 23.8 1.4 0.098 12.8 0.3 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Type_III_YscG PF09477.5 KOS20240.1 - 0.0002 21.4 5.8 0.016 15.2 0.1 3.3 2 2 1 3 3 3 2 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_2 PF07719.12 KOS20240.1 - 0.00023 20.8 0.0 0.00023 20.8 0.0 5.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 KOS20240.1 - 0.00028 20.4 0.1 0.00028 20.4 0.1 3.5 3 2 0 3 3 3 1 TPR repeat TPR_6 PF13174.1 KOS20240.1 - 0.00033 20.9 3.9 0.17 12.4 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 KOS20240.1 - 0.0016 17.5 5.6 0.19 10.7 0.2 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KOS20240.1 - 0.002 17.9 8.5 0.0063 16.3 0.3 3.6 2 2 1 3 3 3 1 Tetratricopeptide repeat PIG-S PF10510.4 KOS20240.1 - 0.0035 16.0 0.9 0.0044 15.7 0.6 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein TPR_16 PF13432.1 KOS20240.1 - 0.0081 16.8 1.1 0.0081 16.8 0.8 5.3 3 2 3 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KOS20240.1 - 0.0087 15.9 11.9 0.066 13.1 0.2 5.0 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 KOS20240.1 - 0.019 15.1 3.2 1.6 9.1 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KOS20240.1 - 0.12 12.9 0.6 0.12 12.9 0.4 5.9 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_5 PF12688.2 KOS20240.1 - 0.29 11.1 9.0 0.62 10.1 0.3 3.3 2 2 1 3 3 3 0 Tetratrico peptide repeat TPR_10 PF13374.1 KOS20240.1 - 2 8.4 9.5 18 5.4 0.2 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat Apc5 PF12862.2 KOS20240.1 - 2.6 7.9 5.8 2.2 8.1 0.1 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_20 PF14561.1 KOS20240.1 - 5.7 7.1 7.9 16 5.7 0.3 3.2 2 2 0 2 2 2 0 Tetratricopeptide repeat Macoilin PF09726.4 KOS20241.1 - 0.018 13.3 12.2 0.019 13.3 8.5 1.0 1 0 0 1 1 1 0 Transmembrane protein FAR1 PF03101.10 KOS20242.1 - 2.5e-08 34.3 0.1 2.5e-08 34.3 0.1 1.9 2 0 0 2 2 2 1 FAR1 DNA-binding domain Med15 PF09606.5 KOS20242.1 - 0.29 9.2 38.7 0.39 8.8 26.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AFT PF08731.6 KOS20242.1 - 0.44 10.7 2.3 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 Transcription factor AFT DUF2939 PF11159.3 KOS20242.1 - 1.4 9.1 0.0 1.4 9.1 0.0 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF2939) HTH_32 PF13565.1 KOS20242.1 - 1.4 9.7 4.3 64 4.4 0.0 3.6 3 0 0 3 3 3 0 Homeodomain-like domain TFIIA PF03153.8 KOS20242.1 - 4.4 7.1 18.6 5.8 6.7 12.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 KOS20242.1 - 5 5.2 42.4 6.2 4.9 29.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HMG-CoA_red PF00368.13 KOS20243.1 - 1.5e-119 399.0 3.9 2.1e-119 398.5 2.7 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KOS20243.1 - 7.1e-39 132.9 0.8 1.2e-38 132.2 0.6 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 KOS20243.1 - 2.1e-14 53.2 6.4 5e-13 48.7 4.5 2.6 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KOS20243.1 - 2e-09 36.0 4.8 2.7e-09 35.5 3.3 1.1 1 0 0 1 1 1 1 Patched family AAA PF00004.24 KOS20245.1 - 9e-16 58.2 0.0 2.5e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KOS20245.1 - 3.1e-13 49.7 0.0 3.4e-12 46.3 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KOS20245.1 - 1e-12 47.5 0.0 8e-10 38.0 0.0 2.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 KOS20245.1 - 7.3e-11 41.9 0.0 1.7e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain RuvB_N PF05496.7 KOS20245.1 - 9.9e-07 28.0 0.0 2.5e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KOS20245.1 - 1.5e-06 28.3 0.0 8e-05 22.7 0.0 2.8 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.1 KOS20245.1 - 1.4e-05 24.7 0.0 3.9e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KOS20245.1 - 2.1e-05 24.5 0.1 0.0014 18.6 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 KOS20245.1 - 2.4e-05 24.0 0.0 3.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 KOS20245.1 - 7.3e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KOS20245.1 - 0.00014 21.7 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KOS20245.1 - 0.0003 19.8 0.0 0.00046 19.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 KOS20245.1 - 0.00043 19.5 0.0 0.017 14.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KOS20245.1 - 0.00091 20.0 0.0 0.0027 18.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 KOS20245.1 - 0.0029 17.2 0.3 0.0085 15.6 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KOS20245.1 - 0.0062 15.9 0.1 0.032 13.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KOS20245.1 - 0.0068 15.3 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 KOS20245.1 - 0.0078 14.9 0.0 0.42 9.2 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 KOS20245.1 - 0.017 14.8 0.1 0.087 12.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 KOS20245.1 - 0.017 14.5 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 KOS20245.1 - 0.018 15.3 0.0 0.045 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KOS20245.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KOS20245.1 - 0.052 13.7 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 KOS20245.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KOS20245.1 - 0.069 12.5 0.1 1.1 8.6 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain AAA_3 PF07726.6 KOS20245.1 - 0.11 12.0 0.0 0.66 9.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 KOS20245.1 - 0.13 11.0 0.0 2.2 6.9 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain ResIII PF04851.10 KOS20245.1 - 0.14 11.9 0.0 0.41 10.4 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2417 PF10329.4 KOS20246.1 - 4.8e-76 255.2 2.8 6.1e-76 254.8 1.9 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 KOS20246.1 - 1.9e-09 37.7 1.8 4.1e-09 36.6 1.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family RhoGAP PF00620.22 KOS20247.1 - 2.7e-36 124.4 0.0 6.7e-36 123.1 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KOS20247.1 - 0.016 15.3 14.6 0.099 12.7 0.6 3.4 4 0 0 4 4 4 0 LIM domain zf-C2H2 PF00096.21 KOS20248.1 - 5.6e-05 23.2 23.0 0.0093 16.2 0.7 5.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS20248.1 - 0.0012 19.0 24.7 0.014 15.6 0.8 5.2 4 1 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KOS20248.1 - 0.0057 16.8 0.2 0.0057 16.8 0.1 4.6 7 0 0 7 7 7 1 Zinc-finger double domain LTV PF04180.9 KOS20248.1 - 0.019 14.4 0.1 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Low temperature viability protein zf-CHCC PF10276.4 KOS20248.1 - 0.037 13.8 3.1 2.9 7.8 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger domain tRNA-synt_1b PF00579.20 KOS20249.1 - 1.1e-56 192.1 0.0 1.3e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF1700 PF08006.6 KOS20249.1 - 0.13 11.5 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF1903 PF08991.5 KOS20250.1 - 0.1 12.7 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Rtt106 PF08512.7 KOS20251.1 - 3.8e-23 81.2 0.0 7.5e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like CENP-T PF15511.1 KOS20251.1 - 0.015 14.5 23.8 0.022 13.9 16.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 KOS20251.1 - 1.9 6.2 39.0 2.8 5.7 27.0 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.5 KOS20252.1 - 1.5e-52 178.2 24.0 1.7e-52 178.1 16.7 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 TP53IP5 PF15331.1 KOS20252.1 - 0.27 11.1 14.5 0.33 10.8 10.0 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Atrophin-1 PF03154.10 KOS20252.1 - 0.44 8.6 19.8 0.6 8.1 13.7 1.2 1 0 0 1 1 1 0 Atrophin-1 family NARP1 PF12569.3 KOS20252.1 - 0.47 9.1 21.0 0.64 8.6 14.6 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NPR3 PF03666.8 KOS20252.1 - 0.98 7.8 9.7 1.2 7.5 6.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MIP-T3 PF10243.4 KOS20252.1 - 2.3 6.5 34.8 3 6.2 24.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 KOS20252.1 - 3 5.7 25.0 3.9 5.3 17.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Paramyxo_ncap PF00973.14 KOS20252.1 - 4 6.0 7.5 3.9 6.0 5.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein BTV_NS2 PF04514.7 KOS20252.1 - 4 6.2 16.1 4.8 5.9 11.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CMV_1a PF12467.3 KOS20252.1 - 4 7.7 18.3 7.4 6.9 12.7 1.4 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF4557 PF15101.1 KOS20252.1 - 4 7.2 11.8 2.9 7.6 7.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4557) FAM60A PF15396.1 KOS20252.1 - 4.1 7.0 16.8 1.8 8.2 9.4 1.8 2 0 0 2 2 2 0 Protein Family FAM60A U79_P34 PF03064.11 KOS20252.1 - 8.2 5.8 22.8 12 5.2 15.8 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 UPF0560 PF10577.4 KOS20252.1 - 8.4 4.5 12.7 9.6 4.3 8.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF1510 PF07423.6 KOS20252.1 - 8.8 5.6 26.7 14 4.9 18.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DSPc PF00782.15 KOS20253.1 - 8.6e-16 57.7 0.0 1.3e-11 44.1 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KOS20253.1 - 0.05 12.9 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KOS20253.1 - 0.069 12.0 0.0 0.087 11.6 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Snf7 PF03357.16 KOS20255.1 - 2.7e-39 134.2 5.6 3.1e-39 134.1 3.9 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.7 KOS20255.1 - 3.4e-05 24.0 0.8 0.011 15.9 0.5 2.6 2 1 1 3 3 2 1 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 KOS20255.1 - 0.0031 16.7 0.6 0.016 14.4 0.1 1.9 1 1 1 2 2 2 1 Reovirus sigma C capsid protein MscS_porin PF12795.2 KOS20255.1 - 0.0048 16.2 9.8 0.26 10.5 2.2 2.9 1 1 2 3 3 3 2 Mechanosensitive ion channel porin domain Exonuc_VII_L PF02601.10 KOS20255.1 - 0.0067 15.6 2.3 0.0088 15.2 1.6 1.0 1 0 0 1 1 1 1 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.4 KOS20255.1 - 0.0091 15.8 12.3 0.28 11.0 9.1 2.3 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliD_C PF07195.7 KOS20255.1 - 0.017 14.4 2.6 0.45 9.7 0.0 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus MitMem_reg PF13012.1 KOS20255.1 - 0.026 14.6 2.5 0.19 11.8 1.7 2.1 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function APG6 PF04111.7 KOS20255.1 - 0.049 12.6 10.3 0.018 14.1 5.5 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 KOS20255.1 - 0.056 13.2 10.9 0.54 10.0 0.0 4.0 2 1 1 3 3 3 0 Prefoldin subunit IFT46_B_C PF12317.3 KOS20255.1 - 0.059 12.7 1.0 0.072 12.4 0.7 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF2312 PF10073.4 KOS20255.1 - 0.061 12.6 2.2 0.14 11.5 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF848 PF05852.6 KOS20255.1 - 0.081 12.7 5.7 0.1 12.4 3.0 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) IncA PF04156.9 KOS20255.1 - 0.099 12.2 7.8 0.21 11.1 0.8 2.3 1 1 1 2 2 2 0 IncA protein NuA4 PF09340.5 KOS20255.1 - 0.11 12.1 2.0 0.23 11.1 1.4 1.6 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 BLOC1_2 PF10046.4 KOS20255.1 - 0.13 12.4 5.7 0.67 10.1 1.8 2.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NYD-SP28_assoc PF14775.1 KOS20255.1 - 0.14 11.8 5.7 2.1 8.1 0.6 3.2 2 1 1 3 3 3 0 Sperm tail C-terminal domain DUF2205 PF10224.4 KOS20255.1 - 0.18 11.3 8.0 0.042 13.4 1.6 2.7 1 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) Peptidase_S46 PF10459.4 KOS20255.1 - 0.2 10.0 5.2 0.25 9.6 3.6 1.0 1 0 0 1 1 1 0 Peptidase S46 COG2 PF06148.6 KOS20255.1 - 0.21 11.4 4.4 0.29 11.0 1.4 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec34 PF04136.10 KOS20255.1 - 0.34 10.5 2.7 1.4 8.5 1.2 2.0 1 1 1 2 2 2 0 Sec34-like family DUF342 PF03961.8 KOS20255.1 - 0.41 8.9 8.0 1.1 7.6 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF972 PF06156.8 KOS20255.1 - 0.42 10.9 7.8 4.1 7.8 3.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 KOS20255.1 - 0.44 9.4 5.3 0.69 8.7 3.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 KOS20255.1 - 0.51 8.7 6.0 1.4 7.2 4.2 1.5 1 1 0 1 1 1 0 AAA domain SlyX PF04102.7 KOS20255.1 - 0.56 10.6 5.8 15 6.0 1.5 3.4 1 1 1 2 2 2 0 SlyX Med4 PF10018.4 KOS20255.1 - 0.6 9.4 7.7 0.79 9.0 0.7 2.6 1 1 2 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 OmpH PF03938.9 KOS20255.1 - 0.65 9.9 13.5 0.11 12.4 5.2 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Mod_r PF07200.8 KOS20255.1 - 1 9.2 10.7 0.47 10.3 4.4 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Mnd1 PF03962.10 KOS20255.1 - 1.9 8.1 10.3 7.9 6.0 7.1 2.0 1 1 0 1 1 1 0 Mnd1 family DUF4140 PF13600.1 KOS20255.1 - 2.3 8.7 6.6 6.2 7.3 0.0 3.5 2 1 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) DUF4337 PF14235.1 KOS20255.1 - 3.3 7.5 6.7 2.2 8.1 3.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) WD40 PF00400.27 KOS20256.1 - 3.7e-37 124.8 2.1 2.1e-06 27.3 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KOS20256.1 - 7.8e-14 51.1 1.8 2.3e-13 49.6 1.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS20256.1 - 2.2e-05 23.9 1.8 3.3e-05 23.4 0.2 2.0 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 KOS20256.1 - 0.00067 17.9 0.0 0.29 9.2 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KOS20256.1 - 0.048 12.4 0.1 1.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Nup133 N terminal like PH_10 PF15411.1 KOS20257.1 - 2e-45 153.7 0.2 4.2e-45 152.6 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KOS20257.1 - 1.4e-34 119.5 0.1 2.6e-34 118.6 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 KOS20257.1 - 1.5e-32 111.4 0.1 2.8e-32 110.6 0.1 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 KOS20257.1 - 2e-08 33.7 0.0 4.9e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 PB1 domain DUF4071 PF13281.1 KOS20257.1 - 0.22 10.3 0.5 0.77 8.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4071) GN3L_Grn1 PF08701.6 KOS20258.1 - 3.7e-25 87.6 16.4 7.5e-25 86.6 11.4 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 KOS20258.1 - 1.5e-20 73.2 0.0 2.8e-14 53.0 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KOS20258.1 - 1.8e-06 27.5 0.0 0.061 12.7 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KOS20258.1 - 1.6e-05 24.8 7.9 0.043 13.6 0.3 3.8 4 1 0 4 4 4 2 Dynamin family FeoB_N PF02421.13 KOS20258.1 - 0.003 16.8 0.5 0.052 12.8 0.1 2.7 2 1 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KOS20258.1 - 0.0087 15.2 0.1 0.018 14.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ORC3_N PF07034.6 KOS20258.1 - 0.037 13.0 0.0 0.065 12.2 0.0 1.4 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Miro PF08477.8 KOS20258.1 - 0.045 14.2 1.0 2 8.9 0.1 2.6 2 1 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 KOS20258.1 - 0.19 11.7 3.4 0.29 11.0 0.1 2.7 1 1 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 KOS20258.1 - 0.29 9.8 5.0 0.075 11.7 0.1 2.1 2 0 0 2 2 2 0 ArgK protein zf-met PF12874.2 KOS20259.1 - 7.8e-06 25.9 1.0 1.4e-05 25.1 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 KOS20259.1 - 0.00028 20.4 0.1 0.00043 19.8 0.1 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 KOS20259.1 - 0.055 12.7 0.9 0.094 12.0 0.6 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CBFD_NFYB_HMF PF00808.18 KOS20261.1 - 8.3e-09 35.3 0.0 2.1e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Nucleo_P87 PF07267.6 KOS20261.1 - 0.016 13.9 7.8 0.018 13.7 5.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Histone PF00125.19 KOS20261.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Daxx PF03344.10 KOS20261.1 - 0.8 8.1 43.3 0.015 13.8 25.4 1.3 2 0 0 2 2 2 0 Daxx Family Phyto_Pns9_10 PF05878.6 KOS20261.1 - 4.1 6.3 8.6 6 5.7 6.0 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Astro_capsid PF03115.9 KOS20261.1 - 6.1 4.9 9.5 7 4.7 6.6 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CRC_subunit PF08624.5 KOS20262.1 - 5.4e-55 185.1 0.0 7.3e-55 184.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit RNB PF00773.14 KOS20263.1 - 1.7e-92 310.1 0.1 2.6e-92 309.5 0.1 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KOS20263.1 - 8.9e-09 35.5 0.1 3e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 PIN domain Cys_Met_Meta_PP PF01053.15 KOS20264.1 - 4.7e-140 466.2 0.1 5.4e-140 466.0 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KOS20264.1 - 2.2e-06 26.8 0.1 3.6e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KOS20264.1 - 2.6e-06 26.4 1.1 4.3e-06 25.7 0.3 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KOS20264.1 - 3.2e-06 26.4 0.5 5.7e-06 25.6 0.3 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family 2-Hacid_dh PF00389.25 KOS20264.1 - 0.025 14.0 0.1 0.036 13.5 0.1 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F-box-like PF12937.2 KOS20265.1 - 0.0046 16.6 0.3 0.02 14.6 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KOS20265.1 - 0.039 13.6 0.1 0.16 11.6 0.1 2.1 1 0 0 1 1 1 0 F-box domain Sporozoite_P67 PF05642.6 KOS20266.1 - 0.44 8.3 4.8 0.41 8.4 3.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Lactamase_B_2 PF12706.2 KOS20267.1 - 4.5e-14 52.4 0.3 6.3e-14 51.9 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KOS20267.1 - 1.4e-06 28.1 0.3 2.4e-06 27.3 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Amidohydro_2 PF04909.9 KOS20267.1 - 0.026 14.0 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase Glyco_transf_34 PF05637.7 KOS20268.1 - 1.5e-07 31.1 2.3 5.3e-07 29.3 1.6 1.7 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 KOS20268.1 - 2.1e-05 24.4 0.1 0.00015 21.6 0.0 2.1 1 1 1 2 2 2 1 Nucleotide-diphospho-sugar transferase Glyco_transf_8 PF01501.15 KOS20268.1 - 0.06 12.6 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 8 Conotoxin PF02950.12 KOS20269.1 - 0.085 13.6 2.3 0.092 13.5 1.6 1.2 1 0 0 1 1 1 0 Conotoxin Toxin_7 PF05980.7 KOS20269.1 - 0.096 12.7 6.7 0.15 12.0 4.6 1.4 1 1 0 1 1 1 0 Toxin 7 Toxin_12 PF07740.7 KOS20269.1 - 0.12 12.8 3.0 0.12 12.8 2.1 2.1 2 1 0 2 2 2 0 Ion channel inhibitory toxin Tachystatin_A PF11406.3 KOS20269.1 - 0.49 10.2 7.0 0.95 9.3 4.8 1.6 1 1 0 1 1 1 0 Antimicrobial peptide tachystatin A UPF0506 PF11703.3 KOS20269.1 - 0.8 9.7 6.3 1.1 9.2 4.3 1.2 1 0 0 1 1 1 0 UPF0506 PS_Dcarbxylase PF02666.10 KOS20271.1 - 4e-46 156.8 0.0 5.5e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.1 KOS20271.1 - 0.036 13.7 0.2 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain DUF2635 PF10948.3 KOS20271.1 - 0.38 10.0 1.5 9.5 5.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2635) Biotin_lipoyl_2 PF13533.1 KOS20271.1 - 0.55 9.9 3.0 2.1 8.0 0.3 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like DUF4407 PF14362.1 KOS20272.1 - 0.00025 20.1 0.6 0.00044 19.2 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) HTH_30 PF13556.1 KOS20272.1 - 0.00049 19.6 1.4 0.0012 18.3 0.1 2.2 3 0 0 3 3 2 1 PucR C-terminal helix-turn-helix domain Phage_GPO PF05929.6 KOS20272.1 - 0.0019 17.5 5.6 0.2 10.8 1.0 2.1 2 0 0 2 2 2 2 Phage capsid scaffolding protein (GPO) serine peptidase Baculo_PEP_C PF04513.7 KOS20272.1 - 0.0038 17.0 2.4 0.14 11.9 0.2 3.1 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.1 KOS20272.1 - 0.0088 15.2 4.8 1.2 8.3 0.9 2.7 2 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding Orthopox_A5L PF06193.6 KOS20272.1 - 0.009 15.9 0.3 2.5 8.0 0.2 2.2 1 1 1 2 2 2 1 Orthopoxvirus A5L protein-like DUF2397 PF09660.5 KOS20272.1 - 0.0096 14.5 8.7 0.013 14.0 6.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) DUF310 PF03750.8 KOS20272.1 - 0.017 15.2 2.1 0.067 13.3 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF310) DUF1664 PF07889.7 KOS20272.1 - 0.032 14.0 5.8 1.8 8.3 1.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Sec5 PF15469.1 KOS20272.1 - 0.038 13.7 4.9 0.8 9.3 0.2 3.1 3 0 0 3 3 3 0 Exocyst complex component Sec5 KIAA1430 PF13879.1 KOS20272.1 - 0.052 13.9 0.8 0.12 12.8 0.1 1.9 2 0 0 2 2 2 0 KIAA1430 homologue DUF77 PF01910.12 KOS20272.1 - 0.085 12.5 0.2 0.4 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF77 Matrilin_ccoil PF10393.4 KOS20272.1 - 0.11 11.8 0.1 0.62 9.4 0.1 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4515 PF14988.1 KOS20272.1 - 0.11 12.1 3.6 0.24 11.0 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4515) LMBR1 PF04791.11 KOS20272.1 - 0.29 9.6 1.2 0.36 9.3 0.6 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein WD40_alt PF14077.1 KOS20272.1 - 0.29 10.7 1.8 0.96 9.1 0.1 2.6 3 0 0 3 3 2 0 Alternative WD40 repeat motif ApoLp-III PF07464.6 KOS20272.1 - 0.41 10.6 2.7 4.6 7.2 0.4 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Rabaptin PF03528.10 KOS20272.1 - 0.45 10.4 6.6 0.56 10.1 0.3 3.2 1 1 1 2 2 2 0 Rabaptin HAMP PF00672.20 KOS20272.1 - 0.46 10.7 2.9 21 5.3 0.1 3.0 2 0 0 2 2 2 0 HAMP domain DivIVA PF05103.8 KOS20272.1 - 0.64 10.0 4.1 13 5.8 0.1 3.1 1 1 2 3 3 3 0 DivIVA protein SNARE PF05739.14 KOS20272.1 - 0.66 9.6 7.1 0.3 10.8 0.2 2.9 3 0 0 3 3 3 0 SNARE domain Prominin PF05478.6 KOS20272.1 - 0.68 7.4 3.2 0.73 7.2 0.9 1.7 1 1 1 2 2 2 0 Prominin DUF2458 PF10454.4 KOS20272.1 - 0.83 9.5 5.1 12 5.8 0.3 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2458) Occludin_ELL PF07303.8 KOS20272.1 - 1.2 9.8 3.8 5.9 7.6 1.1 2.9 1 1 1 2 2 2 0 Occludin homology domain Cep57_CLD_2 PF14197.1 KOS20272.1 - 1.8 8.5 6.2 2.7 7.9 0.1 3.3 3 1 0 3 3 2 0 Centrosome localisation domain of PPC89 LXG PF04740.7 KOS20272.1 - 3 7.5 6.5 4.6 6.9 0.2 2.9 2 1 0 3 3 3 0 LXG domain of WXG superfamily Nucleos_tra2_C PF07662.8 KOS20273.1 - 1.7e-53 181.2 1.2 1.7e-53 181.2 0.8 3.0 4 1 0 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KOS20273.1 - 9.5e-21 73.9 3.1 9.5e-21 73.9 2.2 2.5 1 1 1 2 2 2 1 Na+ dependent nucleoside transporter N-terminus DUF3290 PF11694.3 KOS20273.1 - 7.7 6.2 5.8 0.56 9.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) CLN3 PF02487.12 KOS20275.1 - 2.3e-95 319.7 19.4 8.4e-49 166.4 0.2 3.0 2 1 0 2 2 2 2 CLN3 protein MFS_1 PF07690.11 KOS20275.1 - 2.3e-05 23.2 23.1 0.00028 19.7 16.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Cyt-b5 PF00173.23 KOS20278.1 - 2.8e-21 75.0 0.4 3.1e-21 74.9 0.3 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HhH-GPD PF00730.20 KOS20279.1 - 8.4e-18 64.6 0.0 2e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KOS20279.1 - 2.1e-07 30.2 0.0 5.9e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Med3 PF11593.3 KOS20279.1 - 0.36 10.0 9.2 0.49 9.5 6.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-AN1 PF01428.11 KOS20280.1 - 5.9e-12 45.2 12.2 8.3e-12 44.7 8.5 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger zf-RAG1 PF10426.4 KOS20280.1 - 0.17 11.8 0.7 0.17 11.8 0.5 2.1 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain Metallothio_Euk PF12749.2 KOS20280.1 - 1.3 9.0 9.1 4.2 7.4 6.3 1.7 1 1 0 1 1 1 0 Eukaryotic metallothionein Transp_Tc5_C PF04236.10 KOS20280.1 - 4.1 7.7 6.9 2 8.6 3.4 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Ldl_recept_a PF00057.13 KOS20280.1 - 6 6.8 9.3 2.4 8.1 3.4 2.3 2 1 0 2 2 2 0 Low-density lipoprotein receptor domain class A Nucleopor_Nup85 PF07575.8 KOS20281.1 - 2.2e-13 49.2 0.2 5.8e-12 44.6 0.2 2.5 1 1 0 1 1 1 1 Nup85 Nucleoporin ADH_N PF08240.7 KOS20282.1 - 1.2e-28 99.0 2.3 3e-28 97.7 1.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KOS20282.1 - 2.7e-20 72.2 0.3 5e-20 71.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KOS20282.1 - 0.039 13.3 0.3 0.068 12.5 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MobB PF03205.9 KOS20282.1 - 0.049 13.3 0.4 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Pkinase PF00069.20 KOS20283.1 - 2.1e-09 36.9 0.0 3.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 KOS20283.1 - 3e-09 36.1 3.5 0.061 13.4 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KOS20283.1 - 9.8e-06 25.9 0.0 0.3 11.6 0.0 3.5 2 1 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 KOS20283.1 - 2.8e-05 24.2 0.1 0.0006 20.0 0.1 2.8 1 1 0 2 2 2 1 HEAT repeats Pkinase_Tyr PF07714.12 KOS20283.1 - 0.00014 21.0 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.2 KOS20283.1 - 0.014 15.2 0.0 0.043 13.6 0.0 1.7 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KOS20283.1 - 0.017 15.5 0.1 11 6.4 0.0 2.9 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF3554 PF12074.3 KOS20283.1 - 0.019 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3554) Kinase-like PF14531.1 KOS20283.1 - 0.038 12.9 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Adaptin_N PF01602.15 KOS20283.1 - 0.1 10.9 0.1 0.38 9.0 0.0 1.7 1 1 1 2 2 2 0 Adaptin N terminal region CLASP_N PF12348.3 KOS20283.1 - 0.16 11.3 0.2 0.62 9.3 0.1 1.9 1 1 0 1 1 1 0 CLASP N terminal Aconitase PF00330.15 KOS20284.1 - 1.3e-150 501.9 0.0 4.9e-150 500.0 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KOS20284.1 - 2.5e-37 127.9 0.0 3.7e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 KOS20284.1 - 0.02 13.4 0.0 0.033 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) DUF2462 PF09495.5 KOS20285.1 - 8.1e-10 39.3 10.2 8.1e-10 39.3 7.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) Ribosomal_S10 PF00338.17 KOS20286.1 - 3.2e-27 94.1 0.7 4e-27 93.8 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e MRP-S28 PF10213.4 KOS20287.1 - 3.1e-40 137.1 0.0 4.9e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein LTXXQ PF07813.7 KOS20287.1 - 1.2 9.5 6.0 2.4 8.6 2.1 3.0 3 1 0 3 3 3 0 LTXXQ motif family protein LETM1 PF07766.8 KOS20288.1 - 1.4e-08 34.1 0.2 1.4e-08 34.1 0.1 2.7 3 0 0 3 3 3 1 LETM1-like protein Cwf_Cwc_15 PF04889.7 KOS20288.1 - 0.00053 19.7 5.1 0.00076 19.2 3.6 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3682 PF12446.3 KOS20288.1 - 0.018 15.2 1.5 0.018 15.2 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3682) Pex14_N PF04695.8 KOS20288.1 - 0.39 10.7 5.7 0.65 10.0 4.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.5 KOS20288.1 - 0.43 8.7 19.3 0.53 8.4 13.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDK5_activator PF03261.10 KOS20288.1 - 0.53 9.5 5.4 0.89 8.8 3.7 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein APC_CDC26 PF10471.4 KOS20288.1 - 0.55 10.9 15.7 1.1 10.0 10.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 PAT1 PF09770.4 KOS20288.1 - 2.5 6.2 20.2 3.3 5.8 14.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.3 KOS20288.1 - 3 6.4 27.0 4.2 6.0 18.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4557 PF15101.1 KOS20288.1 - 5.6 6.7 11.0 8.1 6.2 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SCP2 PF02036.12 KOS20289.1 - 4.6e-21 75.0 1.1 5.3e-21 74.8 0.8 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KOS20289.1 - 0.0018 18.2 0.2 0.0023 17.9 0.2 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal NMO PF03060.10 KOS20290.1 - 5.3e-30 104.6 8.2 1.1e-28 100.3 5.7 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KOS20290.1 - 0.019 13.8 4.3 0.029 13.2 3.0 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KOS20290.1 - 0.088 11.6 11.5 0.14 10.9 8.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Aldo_ket_red PF00248.16 KOS20291.1 - 1.8e-67 227.1 0.0 2.1e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DEAD PF00270.24 KOS20292.1 - 1.4e-19 70.1 0.0 1.9e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KOS20292.1 - 1.9e-09 37.6 0.0 2.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KOS20292.1 - 0.016 14.7 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KOS20292.1 - 0.053 12.7 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 KOS20292.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain UTP15_C PF09384.5 KOS20293.1 - 1e-38 132.3 0.0 1.5e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KOS20293.1 - 2.3e-22 77.9 8.5 8.2e-07 28.6 0.0 6.1 6 2 0 6 6 6 3 WD domain, G-beta repeat CAF-1_p150 PF11600.3 KOS20293.1 - 0.0099 15.2 0.8 0.016 14.6 0.5 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal C2 PF00168.25 KOS20294.1 - 1.6e-12 47.1 0.0 2.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain zf-DHHC PF01529.15 KOS20294.1 - 0.18 11.2 1.4 0.28 10.5 0.9 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase RR_TM4-6 PF06459.7 KOS20294.1 - 0.62 9.9 8.4 1.3 8.8 5.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.11 KOS20294.1 - 0.71 9.7 5.7 2.2 8.1 4.0 1.9 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.9 KOS20294.1 - 2 8.0 18.5 0.086 12.5 8.6 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ycf1 PF05758.7 KOS20294.1 - 2.1 5.9 7.9 2.8 5.5 5.5 1.0 1 0 0 1 1 1 0 Ycf1 AAA_23 PF13476.1 KOS20294.1 - 4.1 7.6 12.9 7.1 6.8 8.9 1.3 1 0 0 1 1 1 0 AAA domain DUF1764 PF08576.5 KOS20294.1 - 5.8 7.7 16.1 14 6.4 11.2 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) eIF-3_zeta PF05091.7 KOS20294.1 - 8.4 4.8 15.6 13 4.2 10.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.2 KOS20294.1 - 8.7 3.8 12.7 12 3.4 8.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AvrE PF11725.3 KOS20294.1 - 9.1 3.1 14.9 12 2.7 10.3 1.1 1 0 0 1 1 1 0 Pathogenicity factor GAF_2 PF13185.1 KOS20295.1 - 5.5e-05 23.6 0.1 0.00014 22.4 0.1 1.6 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 KOS20295.1 - 0.0013 18.8 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 KOS20295.1 - 0.0032 17.6 0.1 0.0037 17.3 0.1 1.2 1 0 0 1 1 1 1 GAF domain Zn_clus PF00172.13 KOS20296.1 - 2.2e-08 33.8 12.4 3.4e-08 33.2 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PspA_IM30 PF04012.7 KOS20296.1 - 0.26 10.5 0.0 0.44 9.8 0.0 1.3 1 0 0 1 1 1 0 PspA/IM30 family Helicase_C PF00271.26 KOS20297.1 - 2.7e-07 30.3 0.1 5.5e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RAM PF15320.1 KOS20297.1 - 0.095 12.9 0.3 0.19 12.0 0.2 1.4 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein HET PF06985.6 KOS20298.1 - 2.4e-23 82.8 0.0 4.4e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tektin PF03148.9 KOS20299.1 - 0.044 12.3 0.0 0.072 11.6 0.0 1.3 1 0 0 1 1 1 0 Tektin family DnaJ PF00226.26 KOS20300.1 - 6.2e-11 41.8 0.2 1e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain PC4 PF02229.11 KOS20301.1 - 7.6e-21 73.1 0.0 1.5e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) PXA PF02194.10 KOS20302.1 - 8.6e-36 123.2 0.2 1.9e-35 122.1 0.1 1.6 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 KOS20302.1 - 5.3e-18 65.1 0.4 1.5e-17 63.6 0.0 2.1 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 KOS20302.1 - 1.6e-07 31.0 0.0 4.6e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 PX domain DUF4407 PF14362.1 KOS20302.1 - 0.53 9.1 5.9 0.93 8.3 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pex19 PF04614.7 KOS20303.1 - 2.5e-63 214.0 8.8 4.2e-63 213.2 6.1 1.3 1 0 0 1 1 1 1 Pex19 protein family FliE PF02049.13 KOS20303.1 - 0.094 12.7 7.1 0.41 10.6 0.3 3.4 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE AraC_binding PF02311.14 KOS20303.1 - 0.12 12.0 0.4 3 7.5 0.1 2.4 1 1 1 2 2 2 0 AraC-like ligand binding domain ABC1 PF03109.11 KOS20304.1 - 2.2e-31 108.2 0.0 3.5e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Cytochrom_B561 PF03188.11 KOS20305.1 - 2.2e-08 34.0 10.9 5.6e-08 32.7 7.5 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KOS20305.1 - 6.9e-05 22.3 2.6 6.9e-05 22.3 1.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF1183 PF06682.7 KOS20305.1 - 0.0085 15.7 0.2 0.018 14.6 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) DUF4079 PF13301.1 KOS20305.1 - 0.016 15.2 5.0 0.016 15.2 3.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) PDR_CDR PF06422.7 KOS20305.1 - 0.039 13.6 1.7 4.9 6.8 0.0 2.4 2 0 0 2 2 2 0 CDR ABC transporter PDR_assoc PF08370.6 KOS20305.1 - 0.23 10.9 0.1 0.23 10.9 0.1 1.9 2 0 0 2 2 2 0 Plant PDR ABC transporter associated DUF998 PF06197.8 KOS20305.1 - 0.28 10.4 19.7 0.012 14.8 3.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF998) Ni_hydr_CYTB PF01292.15 KOS20305.1 - 0.31 10.4 11.2 3.1 7.1 8.0 2.3 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 NfeD PF01957.13 KOS20305.1 - 1 9.5 9.2 11 6.1 0.2 2.6 1 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF2970 PF11174.3 KOS20305.1 - 2.3 7.8 8.9 9.6 5.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) MFS_1 PF07690.11 KOS20306.1 - 2.7e-25 88.8 30.3 2.7e-25 88.8 21.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ureidogly_hydro PF04115.7 KOS20307.1 - 1.4e-47 161.1 0.0 1.7e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Ribosomal_L44 PF00935.14 KOS20309.1 - 8.3e-35 118.6 12.4 1.1e-34 118.2 8.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Amidohydro_3 PF07969.6 KOS20310.1 - 2.9e-61 207.8 6.7 4.9e-61 207.1 4.6 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KOS20310.1 - 0.021 14.6 0.0 0.078 12.8 0.0 2.0 1 0 0 1 1 1 0 Amidohydrolase Y_phosphatase3 PF13350.1 KOS20311.1 - 5.3e-33 114.5 0.0 7e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KOS20311.1 - 3e-11 43.2 0.1 1.5e-09 37.7 0.0 2.8 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region PTPlike_phytase PF14566.1 KOS20311.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 KOS20311.1 - 0.041 13.2 0.0 0.059 12.7 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 KOS20311.1 - 0.073 12.4 0.0 0.095 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ALAD PF00490.16 KOS20312.1 - 1.1e-118 395.8 0.0 1.3e-118 395.5 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Acyl_transf_3 PF01757.17 KOS20313.1 - 5.4e-38 130.6 33.0 1.6e-37 129.1 22.9 1.7 1 1 0 1 1 1 1 Acyltransferase family Macoilin PF09726.4 KOS20314.1 - 0.05 11.8 3.8 0.06 11.6 2.7 1.1 1 0 0 1 1 1 0 Transmembrane protein CDK2AP PF09806.4 KOS20314.1 - 0.11 12.7 3.5 0.16 12.2 2.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Zip PF02535.17 KOS20314.1 - 0.12 11.3 14.4 0.16 10.9 10.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CEP170_C PF15308.1 KOS20314.1 - 0.18 10.0 1.6 0.2 9.8 1.1 1.1 1 0 0 1 1 1 0 CEP170 C-terminus PAT1 PF09770.4 KOS20314.1 - 0.33 9.1 9.4 0.36 9.0 6.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SelP_N PF04592.9 KOS20314.1 - 1.8 7.8 19.2 2.6 7.3 13.3 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF605 PF04652.11 KOS20314.1 - 3.3 7.0 9.0 3.8 6.8 6.2 1.1 1 0 0 1 1 1 0 Vta1 like MARVEL PF01284.18 KOS20315.1 - 1.3e-14 54.2 18.3 1.7e-14 53.8 12.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain ParA PF10609.4 KOS20316.1 - 1.9e-34 117.3 0.0 3.6e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KOS20316.1 - 4e-15 55.7 0.0 5.7e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KOS20316.1 - 5.6e-05 23.1 0.0 0.00014 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KOS20316.1 - 0.00062 18.8 0.2 0.0095 15.0 0.1 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase DUF258 PF03193.11 KOS20316.1 - 0.001 18.2 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MipZ PF09140.6 KOS20316.1 - 0.0026 16.8 0.0 0.0043 16.1 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_19 PF13245.1 KOS20316.1 - 0.0095 15.6 0.1 0.068 12.9 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_26 PF13500.1 KOS20316.1 - 0.01 15.4 0.0 0.82 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.13 KOS20316.1 - 0.014 14.5 0.0 0.57 9.3 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 KOS20316.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KOS20316.1 - 0.044 14.0 0.0 0.066 13.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.10 KOS20316.1 - 0.05 12.2 0.0 0.07 11.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ArgK PF03308.11 KOS20316.1 - 0.051 12.3 0.1 0.079 11.7 0.1 1.2 1 0 0 1 1 1 0 ArgK protein NB-ARC PF00931.17 KOS20316.1 - 0.056 12.2 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 KOS20316.1 - 0.058 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KOS20316.1 - 0.066 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PhnA_Zn_Ribbon PF08274.7 KOS20316.1 - 0.067 12.9 0.5 1.4 8.7 0.2 2.6 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Ras PF00071.17 KOS20316.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Ras family T2SE PF00437.15 KOS20316.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.1 KOS20316.1 - 0.12 13.1 0.1 0.28 12.0 0.1 1.8 2 1 0 2 2 1 0 AAA domain DAP3 PF10236.4 KOS20316.1 - 0.17 10.8 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF1279 PF06916.8 KOS20317.1 - 1.8e-27 95.4 0.0 2.5e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L17 PF01196.14 KOS20318.1 - 8.9e-26 90.2 0.0 1.7e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 Serglycin PF04360.7 KOS20318.1 - 0.028 14.1 0.3 0.039 13.6 0.2 1.3 1 0 0 1 1 1 0 Serglycin DALR_1 PF05746.10 KOS20318.1 - 0.075 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 DALR anticodon binding domain UPF0515 PF15135.1 KOS20319.1 - 0.2 10.6 1.1 0.33 9.9 0.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 PSCyt3 PF07627.6 KOS20319.1 - 0.24 11.2 1.5 0.38 10.6 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1588) MRP-S26 PF14943.1 KOS20319.1 - 2.5 7.6 13.1 0.31 10.5 6.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Med26 PF08711.6 KOS20320.1 - 0.046 13.2 0.3 0.077 12.5 0.2 1.4 1 0 0 1 1 1 0 TFIIS helical bundle-like domain CENP-T PF15511.1 KOS20320.1 - 0.19 10.9 11.0 0.21 10.7 7.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PPP4R2 PF09184.6 KOS20320.1 - 0.26 10.7 11.1 0.3 10.5 7.7 1.1 1 0 0 1 1 1 0 PPP4R2 Raftlin PF15250.1 KOS20320.1 - 0.56 8.6 5.1 0.63 8.4 3.5 1.0 1 0 0 1 1 1 0 Raftlin DUF2201_N PF13203.1 KOS20320.1 - 0.57 9.3 8.8 0.59 9.2 6.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Daxx PF03344.10 KOS20320.1 - 1.4 7.3 15.2 1.5 7.1 10.6 1.0 1 0 0 1 1 1 0 Daxx Family Neur_chan_memb PF02932.11 KOS20320.1 - 2.4 7.9 4.6 2.7 7.7 3.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.12 KOS20320.1 - 3 7.5 5.8 4 7.1 4.0 1.2 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 KOS20320.1 - 5.8 6.2 19.1 8 5.7 13.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 KOS20320.1 - 6.4 4.3 6.6 5.7 4.5 4.6 1.1 1 0 0 1 1 1 0 Ycf1 ORC3_N PF07034.6 KOS20321.1 - 8.8e-30 103.7 0.0 3.1e-28 98.7 0.0 2.8 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus RXT2_N PF08595.6 KOS20321.1 - 0.37 10.5 2.9 0.9 9.3 1.2 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Sec63 PF02889.11 KOS20322.1 - 2.5e-196 651.1 0.3 8.5e-109 363.5 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KOS20322.1 - 1.1e-54 184.4 0.7 1e-31 109.7 0.1 3.7 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 KOS20322.1 - 1.4e-16 60.8 0.0 9.1e-09 35.4 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KOS20322.1 - 4.2e-10 39.3 0.0 7.5e-09 35.3 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KOS20322.1 - 9.7e-07 28.9 0.1 0.0015 18.7 0.0 3.1 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KOS20322.1 - 0.00023 20.1 0.0 0.43 9.4 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.11 KOS20322.1 - 0.00035 19.8 0.0 0.071 12.3 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_10 PF12846.2 KOS20322.1 - 0.0022 17.5 0.1 3.5 6.9 0.0 3.8 4 0 0 4 4 4 2 AAA-like domain AAA_19 PF13245.1 KOS20322.1 - 0.016 14.9 0.0 2.8 7.7 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain PWWP PF00855.12 KOS20323.1 - 1.3e-14 54.1 0.0 1.3e-14 54.1 0.0 2.8 3 0 0 3 3 3 1 PWWP domain NPL4 PF05021.10 KOS20324.1 - 2.1e-124 414.6 0.0 2.6e-124 414.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KOS20324.1 - 3.7e-67 224.5 0.0 5.4e-67 224.0 0.0 1.2 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region DUF4451 PF14616.1 KOS20324.1 - 0.12 12.1 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) MoaE PF02391.12 KOS20324.1 - 0.2 11.4 0.0 0.6 9.9 0.0 1.7 1 0 0 1 1 1 0 MoaE protein CPSase_L_D2 PF02786.12 KOS20325.1 - 1.7e-111 370.6 0.0 5e-84 280.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KOS20325.1 - 2.6e-41 140.2 0.2 6.1e-41 139.0 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KOS20325.1 - 1.8e-38 132.1 0.1 4.5e-21 75.4 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 KOS20325.1 - 2.5e-36 124.1 0.0 2.5e-17 62.9 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KOS20325.1 - 1.3e-27 96.3 0.0 2.8e-11 42.7 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KOS20325.1 - 9.6e-22 77.1 0.0 3.4e-10 39.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KOS20325.1 - 6.6e-18 64.8 0.3 4.9e-09 35.8 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KOS20325.1 - 4.2e-09 36.1 0.0 0.0001 21.8 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KOS20325.1 - 1.2e-05 25.2 0.1 0.1 12.4 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KOS20325.1 - 1.4e-05 24.7 0.1 0.12 11.8 0.0 2.8 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 KOS20325.1 - 3.6e-05 23.0 0.0 0.055 12.6 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Sec66 PF09802.4 KOS20326.1 - 7.5e-75 250.4 0.0 8.7e-75 250.2 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF972 PF06156.8 KOS20326.1 - 0.076 13.3 0.4 0.13 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Dicty_REP PF05086.7 KOS20328.1 - 0.71 7.5 3.1 0.74 7.4 2.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_tran_28_C PF04101.11 KOS20329.1 - 6.3e-18 64.9 0.0 4.6e-17 62.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KOS20329.1 - 0.0032 16.7 0.0 0.0039 16.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 UDPGT PF00201.13 KOS20329.1 - 0.066 11.7 0.0 0.085 11.3 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase WD40 PF00400.27 KOS20330.1 - 9.6e-46 152.0 19.7 2.4e-08 33.5 0.1 10.2 11 0 0 11 11 11 8 WD domain, G-beta repeat Gmad1 PF10647.4 KOS20330.1 - 1.3e-05 24.6 11.3 0.0015 17.9 1.4 4.1 4 1 0 4 4 4 2 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 KOS20330.1 - 0.0027 17.3 1.1 4.8 6.9 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 KOS20330.1 - 0.044 12.5 0.0 0.21 10.3 0.0 1.9 2 0 0 2 2 2 0 Coatomer WD associated region VPS28 PF03997.7 KOS20330.1 - 0.29 10.7 0.1 0.89 9.1 0.0 1.7 2 0 0 2 2 2 0 VPS28 protein Senescence_reg PF04520.8 KOS20331.1 - 0.053 14.0 3.9 0.062 13.7 2.7 1.2 1 0 0 1 1 1 0 Senescence regulator Sec3_C PF09763.4 KOS20331.1 - 0.12 10.5 1.6 0.13 10.3 1.1 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 CFEM PF05730.6 KOS20331.1 - 0.5 10.2 11.8 0.84 9.5 7.8 1.7 1 1 0 1 1 1 0 CFEM domain SOG2 PF10428.4 KOS20331.1 - 0.87 8.1 14.3 1.1 7.7 9.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FAM196 PF15265.1 KOS20331.1 - 1.4 8.0 13.9 1.6 7.8 9.7 1.0 1 0 0 1 1 1 0 FAM196 family DUF566 PF04484.7 KOS20331.1 - 1.8 8.0 17.6 2.4 7.6 12.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF572 PF04502.8 KOS20331.1 - 2 7.5 6.6 2.5 7.2 4.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RAP1 PF07218.6 KOS20331.1 - 2.2 6.3 18.3 2.5 6.0 12.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CytochromB561_N PF09786.4 KOS20331.1 - 4.1 5.7 13.6 4.6 5.5 9.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Macoilin PF09726.4 KOS20331.1 - 5.2 5.2 13.6 5.6 5.1 9.4 1.0 1 0 0 1 1 1 0 Transmembrane protein MAP65_ASE1 PF03999.7 KOS20331.1 - 5.6 5.4 11.7 6.7 5.1 8.1 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF202 PF02656.10 KOS20334.1 - 9.5e-14 51.3 5.1 9.5e-14 51.3 3.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) O-antigen_lig PF13425.1 KOS20334.1 - 0.029 14.3 2.7 0.042 13.8 1.9 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF1430 PF07242.6 KOS20334.1 - 0.034 14.2 1.3 2 8.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF2207 PF09972.4 KOS20334.1 - 5.4 5.4 5.7 6.7 5.1 3.9 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.1 KOS20334.1 - 7.4 5.9 7.1 14 5.0 4.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Tctex-1 PF03645.8 KOS20335.1 - 1.4e-33 114.8 0.0 1.6e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Fringe PF02434.11 KOS20337.1 - 0.0096 15.1 0.8 0.15 11.2 0.5 2.4 1 1 0 1 1 1 1 Fringe-like BRE1 PF08647.6 KOS20338.1 - 0.059 13.3 0.3 0.076 12.9 0.2 1.1 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Seryl_tRNA_N PF02403.17 KOS20339.1 - 0.023 14.7 9.9 0.047 13.6 6.9 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 KOS20339.1 - 0.04 13.5 16.2 0.051 13.1 11.2 1.1 1 0 0 1 1 1 0 IncA protein Plasmid_killer PF05015.8 KOS20339.1 - 0.11 12.6 0.8 0.25 11.5 0.6 1.8 1 0 0 1 1 1 0 Plasmid maintenance system killer protein DUF2937 PF11157.3 KOS20339.1 - 0.12 11.7 5.2 0.13 11.5 2.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Herpes_UL6 PF01763.11 KOS20339.1 - 0.12 10.5 4.4 0.15 10.2 3.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF724 PF05266.9 KOS20339.1 - 0.14 11.8 9.3 0.13 11.8 5.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) AAA_13 PF13166.1 KOS20339.1 - 0.15 10.4 4.8 0.19 10.1 3.3 1.1 1 0 0 1 1 1 0 AAA domain PspB PF06667.7 KOS20339.1 - 0.17 11.8 9.0 1.2 9.0 2.2 2.5 1 1 1 2 2 2 0 Phage shock protein B Endotoxin_N PF03945.9 KOS20339.1 - 0.21 10.9 0.9 0.61 9.4 0.1 1.8 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain TelA PF05816.6 KOS20339.1 - 0.22 10.2 10.5 0.37 9.4 7.2 1.3 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) APG6 PF04111.7 KOS20339.1 - 0.25 10.3 14.0 0.25 10.3 9.3 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 FtsQ PF03799.10 KOS20339.1 - 0.66 10.1 4.1 8.8 6.5 0.5 2.3 1 1 1 2 2 2 0 Cell division protein FtsQ DUF3552 PF12072.3 KOS20339.1 - 0.79 8.8 17.6 1.4 8.0 12.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) GP41 PF00517.12 KOS20339.1 - 0.8 9.2 3.2 2.5 7.5 0.8 2.0 1 1 1 2 2 2 0 Retroviral envelope protein Cortex-I_coil PF09304.5 KOS20339.1 - 0.86 9.6 12.3 1.3 9.0 5.8 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil FUSC PF04632.7 KOS20339.1 - 1.1 7.6 8.3 1.1 7.5 5.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DegS PF05384.6 KOS20339.1 - 1.7 7.8 10.6 2.3 7.4 7.3 1.2 1 0 0 1 1 1 0 Sensor protein DegS Allexi_40kDa PF05549.6 KOS20339.1 - 2 7.6 5.5 3.2 6.9 2.7 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein Mnd1 PF03962.10 KOS20339.1 - 2 8.0 13.8 4.1 7.0 9.4 1.6 1 1 0 1 1 1 0 Mnd1 family DUF342 PF03961.8 KOS20339.1 - 3.2 6.0 5.7 3.5 5.9 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ax_dynein_light PF10211.4 KOS20339.1 - 4.2 7.1 13.7 2.4 7.9 7.9 1.8 1 1 0 1 1 1 0 Axonemal dynein light chain CsbD PF05532.7 KOS20339.1 - 5.3 6.7 6.1 0.59 9.8 0.6 2.2 3 0 0 3 3 1 0 CsbD-like Fib_alpha PF08702.5 KOS20339.1 - 7.6 6.6 7.6 3.3 7.8 1.9 1.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family M PF02370.11 KOS20339.1 - 7.7 7.2 6.6 5.3 7.7 1.2 2.9 2 0 0 2 2 2 0 M protein repeat Tmemb_cc2 PF10267.4 KOS20339.1 - 8.4 4.8 13.9 8.8 4.7 8.6 1.8 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein PMEI PF04043.10 KOS20340.1 - 0.12 12.3 1.9 0.29 11.0 0.0 2.4 1 1 2 3 3 3 0 Plant invertase/pectin methylesterase inhibitor DUF940 PF06082.6 KOS20340.1 - 0.21 10.1 4.8 0.26 9.8 3.4 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) DUF572 PF04502.8 KOS20340.1 - 0.71 9.0 14.3 0.94 8.6 9.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4613 PF15390.1 KOS20340.1 - 1.5 6.9 8.2 2.1 6.4 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Neur_chan_memb PF02932.11 KOS20340.1 - 3.2 7.5 6.2 4.5 7.0 4.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cyclin_N PF00134.18 KOS20341.1 - 1.2e-09 37.7 0.0 2.5e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain UPF0121 PF03661.8 KOS20342.1 - 1.6e-10 40.6 2.3 1.9e-10 40.3 1.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF1996 PF09362.5 KOS20343.1 - 4.6e-26 91.9 0.6 7.5e-26 91.2 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF563 PF04577.9 KOS20344.1 - 4.3e-27 95.3 0.0 7.5e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) VSP PF03302.8 KOS20345.1 - 2.9e-07 29.4 0.5 5.1e-07 28.6 0.3 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein Serglycin PF04360.7 KOS20345.1 - 0.11 12.1 0.2 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Serglycin DUF4381 PF14316.1 KOS20345.1 - 0.32 11.1 2.9 0.23 11.5 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF4588 PF15251.1 KOS20346.1 - 6.2e-06 26.3 6.7 2.1e-05 24.6 4.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) DUF2360 PF10152.4 KOS20346.1 - 0.83 9.9 4.0 1.3 9.3 2.8 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) SNF2_N PF00176.18 KOS20347.1 - 3e-81 272.5 0.1 4.8e-81 271.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KOS20347.1 - 3e-44 149.5 2.0 7.4e-44 148.2 1.4 1.7 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 KOS20347.1 - 3.8e-33 114.2 3.6 3.8e-33 114.2 2.5 3.5 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 KOS20347.1 - 3.7e-14 52.3 0.0 1.1e-13 50.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KOS20347.1 - 2e-07 30.1 0.0 5.5e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KOS20347.1 - 2.3e-07 30.8 0.0 1.5e-06 28.1 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KOS20347.1 - 0.00016 21.1 0.0 0.00037 20.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_60s PF00428.14 KOS20347.1 - 0.012 15.9 1.5 0.012 15.9 1.0 5.2 6 0 0 6 6 6 0 60s Acidic ribosomal protein DEAD_2 PF06733.10 KOS20347.1 - 0.029 13.7 0.2 0.067 12.5 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 DUF1777 PF08648.7 KOS20348.1 - 0.02 14.6 39.6 0.032 13.9 27.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DSPc PF00782.15 KOS20349.1 - 3.4e-11 42.8 0.0 5.7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KOS20349.1 - 0.00061 20.0 0.2 0.0011 19.2 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KOS20349.1 - 0.0021 17.4 0.1 0.01 15.2 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KOS20349.1 - 0.019 15.0 0.1 0.034 14.2 0.1 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate p450 PF00067.17 KOS20350.1 - 3.7e-45 154.3 0.0 1.8e-33 115.8 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 WD40 PF00400.27 KOS20352.1 - 2.8e-30 103.0 3.6 4.4e-10 39.0 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 KOS20352.1 - 0.0017 18.0 0.0 1.9 8.1 0.0 3.3 2 2 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KOS20352.1 - 0.0048 15.1 0.1 0.013 13.7 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Gmad1 PF10647.4 KOS20352.1 - 0.0088 15.4 0.3 0.021 14.2 0.2 1.6 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 KOS20352.1 - 0.052 12.2 0.0 0.19 10.4 0.0 1.9 1 1 1 2 2 2 0 Nup133 N terminal like Coatomer_WDAD PF04053.9 KOS20352.1 - 0.099 11.4 0.0 1.1 8.0 0.0 2.0 1 1 1 2 2 2 0 Coatomer WD associated region FTHFS PF01268.14 KOS20353.1 - 4.6e-256 850.1 0.1 6.1e-256 849.7 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KOS20353.1 - 3.8e-67 224.3 1.5 3.8e-67 224.3 1.1 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KOS20353.1 - 3.4e-27 94.8 0.1 7.2e-27 93.7 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Oxidored_q6 PF01058.17 KOS20354.1 - 3.9e-22 78.2 0.0 5.3e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HECT PF00632.20 KOS20355.1 - 7.9e-93 311.0 0.0 1e-92 310.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KOS20355.1 - 2.5e-22 78.3 16.9 1.8e-11 43.6 4.6 2.7 3 0 0 3 3 3 2 WW domain Ion_trans PF00520.26 KOS20356.1 - 2.4e-05 23.6 4.0 0.00029 20.1 2.4 2.0 2 0 0 2 2 2 1 Ion transport protein bZIP_1 PF00170.16 KOS20356.1 - 0.018 14.9 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor DAD PF02109.11 KOS20356.1 - 0.049 13.7 0.2 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 DAD family bZIP_2 PF07716.10 KOS20356.1 - 0.096 12.5 0.3 0.21 11.4 0.2 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Sugarporin_N PF11471.3 KOS20356.1 - 0.1 12.2 0.5 1.2 8.7 0.1 2.4 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF1212 PF06738.7 KOS20356.1 - 8.1 5.8 13.9 1.4 8.3 6.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1212) DSPc PF00782.15 KOS20357.1 - 1.4e-11 44.0 0.1 2.2e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 KOS20357.1 - 0.019 13.8 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase SUV3_C PF12513.3 KOS20358.1 - 1.3e-11 43.7 0.3 3.5e-11 42.3 0.2 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KOS20358.1 - 4.9e-08 32.7 0.1 1.3e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FMO-like PF00743.14 KOS20359.1 - 1.8e-30 105.6 0.0 4.9e-14 51.4 0.0 3.4 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KOS20359.1 - 6.1e-22 78.6 0.3 1.9e-20 73.8 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KOS20359.1 - 2.7e-10 40.4 0.0 0.00013 21.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KOS20359.1 - 1.1e-09 37.6 0.2 3.8e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KOS20359.1 - 4.2e-09 36.3 0.3 6.3e-08 32.5 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KOS20359.1 - 1.7e-08 34.4 5.2 2.3e-06 27.4 1.1 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KOS20359.1 - 1.3e-07 31.1 0.0 0.0033 16.5 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 KOS20359.1 - 1.5e-06 27.4 0.7 1.5e-06 27.4 0.5 3.4 3 1 1 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.12 KOS20359.1 - 3e-06 26.5 1.3 7.6e-06 25.1 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KOS20359.1 - 4.9e-06 26.8 4.9 5.9e-05 23.4 0.1 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KOS20359.1 - 6.4e-05 22.5 1.1 0.007 15.9 0.1 2.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 KOS20359.1 - 7.3e-05 22.8 0.1 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 KOS20359.1 - 0.00024 20.3 0.0 0.00039 19.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KOS20359.1 - 0.00038 19.4 0.0 0.00088 18.2 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KOS20359.1 - 0.00066 18.6 0.0 0.0015 17.4 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KOS20359.1 - 0.00075 18.6 0.6 0.0018 17.4 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KOS20359.1 - 0.00093 17.7 0.3 0.0018 16.8 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_10 PF13460.1 KOS20359.1 - 0.00095 19.2 2.5 0.027 14.4 0.2 2.8 3 0 0 3 3 2 1 NADH(P)-binding 3HCDH_N PF02737.13 KOS20359.1 - 0.00097 18.8 1.3 0.0022 17.6 0.1 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KOS20359.1 - 0.0065 16.6 0.0 3.5 7.9 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_2 PF03446.10 KOS20359.1 - 0.031 14.1 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Lycopene_cycl PF05834.7 KOS20359.1 - 0.088 11.7 0.2 0.67 8.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein CPSase_L_chain PF00289.17 KOS20359.1 - 0.097 12.7 0.4 18 5.4 0.1 2.5 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain UDPG_MGDP_dh_N PF03721.9 KOS20359.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.7 KOS20359.1 - 0.21 10.9 0.9 0.53 9.6 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 KOS20359.1 - 2.1 8.1 4.9 0.85 9.4 0.2 2.3 2 0 0 2 2 2 0 ThiF family Tyrosinase PF00264.15 KOS20360.1 - 3e-14 53.7 3.1 6.6e-12 46.0 0.7 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase DUF2235 PF09994.4 KOS20361.1 - 3.6e-104 348.0 0.9 4.8e-104 347.5 0.6 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) ECH PF00378.15 KOS20362.1 - 7.3e-49 166.0 0.0 6.4e-38 130.2 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family CAF1A PF12253.3 KOS20363.1 - 5.8 7.0 7.9 0.29 11.2 0.2 2.5 3 0 0 3 3 3 0 Chromatin assembly factor 1 subunit A Ribonuclease_3 PF00636.21 KOS20364.1 - 9e-39 132.4 1.9 3.8e-20 72.4 0.0 3.7 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KOS20364.1 - 3.2e-22 78.8 0.0 2.3e-10 40.5 0.0 3.7 3 0 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.26 KOS20364.1 - 4.6e-17 61.6 0.1 1.4e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 KOS20364.1 - 1.2e-14 53.8 0.2 2.5e-12 46.3 0.1 2.7 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.24 KOS20364.1 - 3.5e-11 42.8 0.0 7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KOS20364.1 - 2.2e-10 40.6 1.7 2.4e-10 40.5 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Dynamin_N PF00350.18 KOS20365.1 - 8.2e-24 84.3 0.5 7e-15 55.2 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Dynamin_M PF01031.15 KOS20365.1 - 3.5e-16 58.8 0.0 6.3e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 KOS20365.1 - 2.4e-06 27.3 0.8 0.00072 19.3 0.0 3.7 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KOS20365.1 - 4.6e-05 23.3 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KOS20365.1 - 0.0023 18.4 0.2 0.012 16.1 0.0 2.3 3 0 0 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 KOS20365.1 - 0.0045 16.4 0.0 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 KOS20365.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Ras family FeoB_N PF02421.13 KOS20365.1 - 0.1 11.8 0.1 1.4 8.1 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_21 PF13304.1 KOS20365.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Tho2 PF11262.3 KOS20366.1 - 6.6e-71 238.7 0.1 1.3e-70 237.8 0.1 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KOS20366.1 - 9e-27 92.6 0.6 3.2e-26 90.9 0.0 2.3 3 0 0 3 3 3 1 Transcription- and export-related complex subunit GATase PF00117.23 KOS20370.1 - 1.9e-09 37.2 0.0 2.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I IER PF05760.7 KOS20371.1 - 0.031 14.1 4.7 0.033 14.1 3.3 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) SOG2 PF10428.4 KOS20371.1 - 0.05 12.2 7.6 0.048 12.3 5.3 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Senescence_reg PF04520.8 KOS20371.1 - 1.6 9.1 4.9 2.2 8.7 3.4 1.1 1 0 0 1 1 1 0 Senescence regulator Myf5 PF12232.3 KOS20371.1 - 4.9 7.8 12.7 8.7 7.0 8.8 1.5 1 0 0 1 1 1 0 Myogenic determination factor 5 Ashwin PF15323.1 KOS20371.1 - 7.4 6.5 8.2 9.1 6.2 5.7 1.1 1 0 0 1 1 1 0 Developmental protein Fungal_trans_2 PF11951.3 KOS20372.1 - 0.0046 15.6 0.0 0.0074 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KOS20373.1 - 4.3e-07 29.0 3.1 0.012 14.4 0.6 2.5 2 1 1 3 3 3 2 Fungal specific transcription factor domain RabGAP-TBC PF00566.13 KOS20374.1 - 8.5e-49 165.9 0.0 1.6e-48 165.0 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf-RING_2 PF13639.1 KOS20375.1 - 3.8e-09 36.2 7.5 8.7e-09 35.0 5.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KOS20375.1 - 9.9e-07 28.7 4.6 4.3e-06 26.7 3.2 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KOS20375.1 - 7.5e-06 25.7 3.6 0.00012 21.8 2.2 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KOS20375.1 - 9.9e-06 25.4 7.9 2.8e-05 23.9 5.5 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 KOS20375.1 - 0.00062 19.7 7.7 0.0013 18.6 5.3 1.6 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.20 KOS20375.1 - 0.0027 17.3 9.0 0.0066 16.0 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS20375.1 - 0.0031 17.1 5.1 0.006 16.2 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 KOS20375.1 - 0.005 16.5 3.2 0.005 16.5 2.2 1.9 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 KOS20375.1 - 0.1 12.6 13.3 0.019 15.0 6.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KOS20375.1 - 0.12 12.4 7.4 0.24 11.4 5.1 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_5 PF14634.1 KOS20375.1 - 0.32 10.7 8.4 0.58 9.9 5.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Baculo_RING PF05883.6 KOS20375.1 - 0.53 10.1 2.7 1.6 8.5 1.9 1.8 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain PHD PF00628.24 KOS20375.1 - 3.3 7.4 6.6 6.4 6.5 4.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 KOS20375.1 - 4 7.1 7.1 72 3.0 4.9 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PS_Dcarbxylase PF02666.10 KOS20376.1 - 5.7e-52 175.9 0.0 8.3e-52 175.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 KOS20376.1 - 1.4e-22 79.3 0.0 8.6e-14 51.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 KOS20376.1 - 0.0023 18.0 0.7 0.0065 16.5 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KOS20376.1 - 0.0038 16.4 0.0 0.013 14.7 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 KOS20376.1 - 0.059 12.9 0.0 0.22 11.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 KOS20376.1 - 0.18 11.7 2.0 0.42 10.6 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain DUF3712 PF12505.3 KOS20377.1 - 0.13 12.2 0.0 0.78 9.7 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3712) ICL PF00463.16 KOS20378.1 - 2.8e-258 857.4 0.0 2.1e-257 854.4 0.0 1.9 1 1 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KOS20378.1 - 4.5e-12 45.7 0.0 1.2e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Pkinase PF00069.20 KOS20379.1 - 1.7e-74 250.2 0.0 2.3e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS20379.1 - 3.8e-38 131.0 0.0 5.9e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 KOS20379.1 - 1.7e-16 60.1 0.3 4e-16 58.9 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 KOS20379.1 - 7.3e-07 28.4 0.0 2.4e-06 26.7 0.0 1.7 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KOS20379.1 - 0.00027 20.3 0.0 0.00057 19.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 KOS20379.1 - 0.0025 16.4 0.0 0.0038 15.8 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC COX6B PF02297.12 KOS20380.1 - 8.2e-18 64.1 5.6 9.5e-18 63.9 3.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 KOS20380.1 - 0.014 14.7 2.3 0.016 14.5 1.4 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain ketoacyl-synt PF00109.21 KOS20380.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain UPF0203 PF05254.7 KOS20380.1 - 5 7.0 6.7 2.3 8.1 0.9 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) B12D PF06522.6 KOS20381.1 - 1.1e-06 28.2 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit S10_plectin PF03501.10 KOS20382.1 - 1.9e-39 133.4 0.1 2.3e-39 133.1 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Telomere_Sde2 PF13019.1 KOS20383.1 - 1.6e-63 213.2 0.1 2.3e-63 212.7 0.1 1.2 1 0 0 1 1 1 1 Telomere stability and silencing DUF1675 PF07897.6 KOS20383.1 - 0.017 15.0 9.0 0.022 14.6 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Serglycin PF04360.7 KOS20383.1 - 0.54 9.9 8.7 0.83 9.3 5.5 1.6 1 1 1 2 2 2 0 Serglycin Gp_dh_C PF02800.15 KOS20384.1 - 1.9e-75 251.5 0.1 2.8e-75 251.0 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KOS20384.1 - 7.4e-58 194.7 0.1 1.4e-57 193.9 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KOS20384.1 - 0.045 13.6 0.5 0.14 12.1 0.4 2.0 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 KOS20384.1 - 0.09 11.9 0.1 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SprA-related PF12118.3 KOS20385.1 - 0.00059 19.2 15.3 0.00066 19.0 10.6 1.1 1 0 0 1 1 1 1 SprA-related family RR_TM4-6 PF06459.7 KOS20385.1 - 0.0081 16.0 17.5 0.011 15.5 12.2 1.3 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 AAA_23 PF13476.1 KOS20385.1 - 0.013 15.7 6.7 0.016 15.5 4.7 1.2 1 0 0 1 1 1 0 AAA domain BAF1_ABF1 PF04684.8 KOS20385.1 - 0.096 11.5 14.9 0.12 11.1 10.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF605 PF04652.11 KOS20385.1 - 0.13 11.6 18.8 0.14 11.4 13.0 1.1 1 0 0 1 1 1 0 Vta1 like Paf1 PF03985.8 KOS20385.1 - 0.17 10.6 17.4 0.25 10.0 12.1 1.3 1 0 0 1 1 1 0 Paf1 Ycf1 PF05758.7 KOS20385.1 - 0.27 8.9 10.4 0.3 8.7 7.2 1.2 1 0 0 1 1 1 0 Ycf1 IncA PF04156.9 KOS20385.1 - 0.86 9.1 12.6 1.2 8.6 8.7 1.3 1 0 0 1 1 1 0 IncA protein Cyclin_N PF00134.18 KOS20385.1 - 0.87 9.1 4.2 2.3 7.7 2.9 1.8 1 0 0 1 1 1 0 Cyclin, N-terminal domain GAGA_bind PF06217.7 KOS20385.1 - 1.1 9.2 9.6 1.4 8.8 6.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3381 PF11861.3 KOS20385.1 - 1.6 8.2 18.3 3.3 7.2 12.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) RAM PF15320.1 KOS20385.1 - 1.6 9.0 13.9 0.048 13.9 5.3 1.7 2 0 0 2 2 1 0 mRNA cap methylation, RNMT-activating mini protein DDRGK PF09756.4 KOS20385.1 - 2.1 7.7 22.2 4.1 6.7 15.4 1.4 1 0 0 1 1 1 0 DDRGK domain CDC45 PF02724.9 KOS20385.1 - 3.3 5.6 13.4 4.6 5.1 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein AIF_C PF14721.1 KOS20385.1 - 3.7 7.8 10.4 0.47 10.7 4.3 1.7 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MAT1 PF06391.8 KOS20385.1 - 4.7 6.7 23.4 8.2 5.9 14.6 2.0 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 CobT PF06213.7 KOS20385.1 - 6.2 5.8 17.9 9.7 5.2 12.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Hid1 PF12722.2 KOS20385.1 - 6.6 4.2 9.1 7.7 4.0 6.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TRAP_alpha PF03896.11 KOS20385.1 - 8.7 5.2 11.6 16 4.3 8.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Serinc PF03348.10 KOS20385.1 - 9.1 4.8 7.8 12 4.4 5.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) PEX11 PF05648.9 KOS20385.1 - 9.6 5.3 8.1 17 4.6 5.6 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) RRM_1 PF00076.17 KOS20386.1 - 1.3e-16 59.9 0.0 2e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS20386.1 - 4.6e-15 55.3 0.0 8.4e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS20386.1 - 3e-05 23.7 0.0 4.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Packaging_FI PF14000.1 KOS20386.1 - 0.011 15.8 1.0 0.016 15.3 0.7 1.4 1 0 0 1 1 1 0 DNA packaging protein FI IncA PF04156.9 KOS20386.1 - 0.012 15.1 2.3 0.015 14.8 1.6 1.1 1 0 0 1 1 1 0 IncA protein CASP_C PF08172.7 KOS20386.1 - 0.017 14.1 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 CASP C terminal V_ATPase_I PF01496.14 KOS20386.1 - 0.018 12.8 0.5 0.022 12.6 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 KOS20386.1 - 0.034 14.4 0.4 0.064 13.5 0.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Nup35_RRM_2 PF14605.1 KOS20386.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DivIC PF04977.10 KOS20386.1 - 0.17 11.4 6.5 0.26 10.8 4.5 1.2 1 0 0 1 1 1 0 Septum formation initiator APG6 PF04111.7 KOS20386.1 - 0.18 10.8 3.1 0.21 10.6 2.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 EMP24_GP25L PF01105.19 KOS20386.1 - 0.2 11.3 0.7 0.28 10.8 0.5 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD WD40_alt PF14077.1 KOS20386.1 - 0.22 11.1 1.0 0.41 10.3 0.7 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif T2SM PF04612.7 KOS20386.1 - 1 9.1 3.8 1.5 8.5 2.7 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M XhlA PF10779.4 KOS20386.1 - 1.2 9.0 3.6 1.9 8.4 2.5 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DUF4337 PF14235.1 KOS20386.1 - 1.5 8.6 5.1 2.1 8.1 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) GRP PF07172.6 KOS20386.1 - 2 8.9 16.4 0.043 14.2 6.1 2.0 2 1 0 2 2 2 0 Glycine rich protein family Lum_binding PF00677.12 KOS20387.1 - 1.6e-38 130.4 0.0 6.9e-20 70.7 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain HABP4_PAI-RBP1 PF04774.10 KOS20388.1 - 0.0024 18.3 1.7 0.0042 17.5 1.1 1.6 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family SH2_2 PF14633.1 KOS20389.1 - 3.6e-78 261.6 1.2 5.1e-78 261.1 0.0 1.9 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 KOS20389.1 - 6.4e-37 126.1 1.5 6.4e-37 126.1 1.0 4.3 5 0 0 5 5 5 1 Death-like domain of SPT6 HHH_7 PF14635.1 KOS20389.1 - 2.1e-31 108.1 0.0 4.7e-31 106.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 KOS20389.1 - 6.4e-30 103.6 0.0 2.5e-29 101.7 0.0 2.1 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 KOS20389.1 - 5.3e-25 87.4 25.4 5.3e-25 87.4 17.6 6.4 4 1 1 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 KOS20389.1 - 4.5e-18 65.3 2.2 2.5e-17 62.9 1.5 2.2 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 KOS20389.1 - 2.8e-05 23.8 0.0 7.8e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 SH2 domain S1 PF00575.18 KOS20389.1 - 0.00029 20.8 0.1 0.00062 19.8 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.2 KOS20389.1 - 0.00045 20.1 0.0 0.0038 17.1 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif Perilipin PF03036.11 KOS20390.1 - 0.00068 18.5 0.0 0.0013 17.6 0.0 1.4 1 1 0 1 1 1 1 Perilipin family Ribosomal_60s PF00428.14 KOS20390.1 - 0.34 11.3 2.3 0.55 10.6 1.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein APH PF01636.18 KOS20391.1 - 0.052 13.2 5.7 0.19 11.4 4.0 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pirin PF02678.11 KOS20392.1 - 8.8e-32 109.1 0.0 1.6e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 KOS20392.1 - 4e-25 87.9 0.0 1.2e-24 86.3 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KOS20392.1 - 1.6e-06 27.4 1.5 0.00012 21.5 1.1 2.4 2 0 0 2 2 2 2 Cupin domain CFEM PF05730.6 KOS20393.1 - 2e-08 33.8 5.4 3.8e-08 33.0 3.8 1.5 1 0 0 1 1 1 1 CFEM domain Herpes_capsid PF06112.6 KOS20393.1 - 1.5 8.8 7.6 2.3 8.2 5.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ribonuc_red_lgC PF02867.10 KOS20394.1 - 3.7e-220 732.0 0.0 5e-220 731.6 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KOS20394.1 - 4.7e-24 83.9 0.0 1.5e-23 82.3 0.0 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KOS20394.1 - 2.5e-17 63.0 0.1 1.1e-16 61.0 0.0 2.2 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 KOS20394.1 - 0.077 11.0 0.0 0.12 10.3 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase TatD_DNase PF01026.16 KOS20395.1 - 9.6e-46 156.0 0.0 1e-44 152.6 0.0 1.9 1 1 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 KOS20395.1 - 0.046 13.2 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase CENP-N PF05238.8 KOS20396.1 - 5.5e-113 378.0 0.0 6.5e-113 377.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.10 KOS20397.1 - 1.4e-12 47.1 11.6 2.3e-12 46.5 8.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KOS20397.1 - 0.00014 21.7 14.1 0.00049 19.9 9.8 1.9 1 1 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 KOS20397.1 - 0.058 13.3 0.9 0.12 12.3 0.6 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family XhlA PF10779.4 KOS20397.1 - 0.22 11.4 4.8 0.45 10.4 3.3 1.6 1 1 0 1 1 1 0 Haemolysin XhlA IncA PF04156.9 KOS20397.1 - 0.57 9.7 5.2 0.77 9.3 3.6 1.2 1 0 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 KOS20397.1 - 1.4 8.9 10.0 1.1 9.3 5.5 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 KOS20397.1 - 2.7 8.4 6.0 2.2 8.6 2.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) M20_dimer PF07687.9 KOS20398.1 - 0.027 14.1 0.2 0.045 13.4 0.1 1.6 1 1 0 1 1 1 0 Peptidase dimerisation domain Ank_2 PF12796.2 KOS20399.1 - 1.8e-10 40.9 0.0 1.8e-09 37.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KOS20399.1 - 8e-09 34.8 0.0 0.0019 17.9 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KOS20399.1 - 4.5e-07 29.4 0.0 0.043 14.0 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KOS20399.1 - 2.3e-06 27.6 0.0 0.0017 18.5 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KOS20399.1 - 2.4e-06 27.9 0.0 1.9e-05 24.9 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) peroxidase PF00141.18 KOS20400.1 - 3.4e-84 281.9 0.0 8.6e-47 159.5 0.0 2.3 2 1 0 2 2 2 2 Peroxidase Glyoxalase_2 PF12681.2 KOS20401.1 - 4.1e-09 37.0 0.1 5e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KOS20401.1 - 2.4e-08 34.0 0.4 4e-08 33.2 0.3 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MFS_1 PF07690.11 KOS20402.1 - 3.2e-25 88.5 50.9 7.4e-23 80.8 36.6 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS20402.1 - 7.8e-17 60.9 16.4 7.8e-17 60.9 11.4 3.4 1 1 1 3 3 3 1 Sugar (and other) transporter RskA PF10099.4 KOS20402.1 - 4.7 6.9 9.0 6.1 6.5 0.6 3.5 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Glyco_hydro_18 PF00704.23 KOS20403.1 - 1.8e-12 47.4 0.3 1.8e-12 47.4 0.2 2.2 2 1 1 3 3 3 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 KOS20403.1 - 1.5e-10 40.5 11.0 5.1e-10 38.8 7.7 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain MFS_1 PF07690.11 KOS20404.1 - 1.2e-44 152.4 35.6 1.4e-43 149.0 9.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 KOS20405.1 - 1.4e-54 184.8 0.3 2.1e-54 184.3 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KOS20405.1 - 4.6e-09 35.5 0.1 1.3e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KOS20405.1 - 3.6e-06 26.7 0.1 5.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS20405.1 - 3.6e-05 23.0 0.0 0.0037 16.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KOS20405.1 - 0.0036 17.2 1.7 0.0095 15.8 1.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Sugar_tr PF00083.19 KOS20406.1 - 5e-80 269.2 29.7 5.7e-80 269.0 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS20406.1 - 7.1e-28 97.3 57.6 3e-21 75.5 24.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3309 PF11752.3 KOS20406.1 - 0.52 10.1 5.8 0.33 10.7 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DUF21 PF01595.15 KOS20406.1 - 8.9 5.5 12.1 2.8 7.1 5.5 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF21 P5CR_dimer PF14748.1 KOS20407.1 - 6.9e-40 135.3 2.2 3e-39 133.3 0.2 2.4 3 0 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KOS20407.1 - 1.5e-17 63.7 0.5 2.9e-17 62.8 0.4 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KOS20407.1 - 0.00027 20.7 3.9 0.0075 16.0 2.7 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PDH PF02153.12 KOS20407.1 - 0.0059 15.5 0.1 0.0097 14.8 0.1 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase Shikimate_DH PF01488.15 KOS20407.1 - 0.07 13.2 0.1 0.38 10.8 0.0 2.2 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 KOS20407.1 - 0.078 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.4 KOS20407.1 - 0.078 12.7 0.6 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 Rossmann-like domain ApbA PF02558.11 KOS20407.1 - 0.13 11.6 0.6 0.32 10.4 0.4 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA E1-E2_ATPase PF00122.15 KOS20408.1 - 1.1e-57 194.6 0.9 2.2e-57 193.7 0.6 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KOS20408.1 - 5.1e-35 121.8 0.0 3.1e-29 102.9 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KOS20408.1 - 4.6e-32 111.0 0.0 4.6e-32 111.0 0.0 1.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KOS20408.1 - 1.3e-14 53.9 0.0 2.9e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KOS20408.1 - 9e-14 52.0 0.0 1.8e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KOS20408.1 - 3.6e-13 48.7 0.0 7.5e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KOS20408.1 - 1.5e-05 24.6 0.1 0.00098 18.7 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.16 KOS20409.1 - 5e-43 146.9 0.0 7e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family SAGA-Tad1 PF12767.2 KOS20410.1 - 4.1e-53 180.6 0.0 6.2e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Spc97_Spc98 PF04130.8 KOS20411.1 - 3.9e-112 375.3 0.0 5.1e-112 374.9 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family PLA2_B PF01735.13 KOS20412.1 - 1.7e-177 590.4 3.1 2.2e-177 590.1 2.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Menin PF05053.8 KOS20413.1 - 0.087 10.9 8.0 0.11 10.5 5.6 1.2 1 0 0 1 1 1 0 Menin CDC45 PF02724.9 KOS20413.1 - 0.26 9.2 6.7 0.34 8.8 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RCR PF12273.3 KOS20413.1 - 0.33 11.4 4.8 0.54 10.8 3.3 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Herpes_LMP2 PF07415.6 KOS20413.1 - 3.6 6.0 8.8 7.6 5.0 5.8 1.6 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein Dynactin PF12455.3 KOS20414.1 - 5.5e-88 294.4 4.3 5.5e-88 294.4 3.0 3.8 3 1 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 KOS20414.1 - 5.5e-21 74.0 0.3 1e-20 73.2 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF2353 PF09789.4 KOS20414.1 - 0.0015 17.8 26.0 0.0015 17.8 18.0 4.6 2 2 1 3 3 3 1 Uncharacterized coiled-coil protein (DUF2353) HALZ PF02183.13 KOS20414.1 - 6.6 6.5 32.4 0.15 11.8 1.0 6.7 5 1 1 6 6 6 0 Homeobox associated leucine zipper HMG_box PF00505.14 KOS20415.1 - 1.6e-21 76.2 1.9 2.7e-21 75.6 1.3 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KOS20415.1 - 0.00017 21.9 0.5 0.0004 20.6 0.3 1.6 1 0 0 1 1 1 1 HMG-box domain SRP19 PF01922.12 KOS20417.1 - 1.1e-28 99.6 0.0 2e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein DEC-1_N PF04625.8 KOS20417.1 - 2.4 6.7 8.3 3.5 6.1 5.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Cyt-b5 PF00173.23 KOS20418.1 - 4.4e-18 64.8 0.2 1.6e-17 63.0 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KOS20418.1 - 4.1e-08 33.6 20.0 5.6e-08 33.1 12.5 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PP2C PF00481.16 KOS20420.1 - 7.6e-37 127.0 0.0 9.6e-31 107.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KOS20420.1 - 2.5e-05 23.7 0.1 0.00054 19.4 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C Het-C PF07217.6 KOS20421.1 - 3.8e-282 936.9 0.0 4.7e-282 936.6 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Cu-oxidase_3 PF07732.10 KOS20422.1 - 3.2e-45 152.6 3.6 2.5e-41 140.1 0.7 3.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KOS20422.1 - 4.7e-41 139.5 5.7 2.2e-35 121.1 0.2 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KOS20422.1 - 3.3e-37 127.8 1.8 8.1e-34 116.8 0.2 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.1 KOS20422.1 - 0.0024 17.7 0.0 7.9 6.4 0.0 3.6 3 1 0 3 3 3 1 Cupredoxin-like domain FTR1 PF03239.9 KOS20423.1 - 2.5e-77 259.8 9.0 3e-77 259.5 6.2 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4231 PF14015.1 KOS20423.1 - 0.065 13.2 0.5 0.065 13.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) RRM_1 PF00076.17 KOS20424.1 - 1.8e-38 129.9 0.3 5.6e-18 64.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS20424.1 - 3.6e-30 103.7 0.1 3.9e-15 55.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS20424.1 - 4.5e-14 52.0 0.1 4.6e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KOS20424.1 - 7.3e-05 22.4 0.1 0.041 13.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KOS20424.1 - 0.081 12.7 0.1 16 5.3 0.0 2.8 2 0 0 2 2 2 0 RNA binding motif Ribosomal_L18p PF00861.17 KOS20425.1 - 3.7e-43 146.4 0.3 9e-43 145.2 0.1 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KOS20425.1 - 1.8e-32 111.7 7.1 1.8e-32 111.7 4.9 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region CTP_transf_2 PF01467.21 KOS20426.1 - 3.3e-23 82.4 0.0 6.1e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase adh_short PF00106.20 KOS20427.1 - 1.3e-16 60.9 1.3 2.3e-16 60.1 0.0 2.0 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 KOS20427.1 - 5e-09 36.0 0.0 1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KOS20427.1 - 3.8e-06 26.5 0.0 5.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KOS20427.1 - 4.4e-05 23.3 0.4 0.0025 17.6 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KOS20427.1 - 0.0038 17.2 0.4 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Ldh_1_N PF00056.18 KOS20427.1 - 0.028 14.2 0.0 7.3 6.4 0.0 2.6 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Sulfate_transp PF00916.15 KOS20428.1 - 0.00017 20.7 2.0 0.00017 20.7 1.4 2.9 2 1 1 3 3 3 1 Sulfate transporter family HSP20 PF00011.16 KOS20430.1 - 1.5e-17 63.3 0.5 7.1e-12 45.0 0.4 2.8 2 1 0 2 2 2 2 Hsp20/alpha crystallin family DUF853 PF05872.7 KOS20430.1 - 0.19 10.0 0.8 0.23 9.7 0.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF2868 PF11067.3 KOS20430.1 - 0.25 10.4 2.0 0.34 10.0 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Proteasome PF00227.21 KOS20431.1 - 2.1e-29 102.1 0.2 3.7e-29 101.3 0.2 1.4 1 1 0 1 1 1 1 Proteasome subunit Pkinase PF00069.20 KOS20432.1 - 1.4e-29 103.0 0.0 1.9e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS20432.1 - 1.5e-07 30.7 0.0 2.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF508 PF04370.7 KOS20432.1 - 0.28 10.8 3.9 0.53 9.9 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Secretin_N_2 PF07655.8 KOS20432.1 - 1.3 9.4 15.9 0.82 10.0 1.6 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain TPR_11 PF13414.1 KOS20433.1 - 0.093 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 TPR repeat NAD_binding_6 PF08030.7 KOS20434.1 - 6.8e-19 68.3 0.0 9.4e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KOS20434.1 - 2.9e-15 56.4 11.4 5.7e-15 55.5 7.9 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KOS20434.1 - 4.6e-08 32.8 0.0 9.9e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KOS20434.1 - 0.01 16.4 0.0 1.6 9.3 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Rad51 PF08423.6 KOS20435.1 - 1.8e-137 456.3 0.0 2.3e-137 455.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KOS20435.1 - 2.6e-13 49.7 0.0 3.9e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 KOS20435.1 - 1.6e-07 31.3 1.2 4e-07 30.0 0.2 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 KOS20435.1 - 1e-06 28.0 0.0 1.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KOS20435.1 - 1.7e-06 27.3 0.0 3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 KOS20435.1 - 0.016 14.0 0.0 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 KOS20435.1 - 0.091 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 PAXNEB protein Per1 PF04080.8 KOS20436.1 - 2.3e-107 358.4 3.8 2.8e-107 358.1 2.6 1.1 1 0 0 1 1 1 1 Per1-like Aldedh PF00171.17 KOS20437.1 - 3.7e-106 355.2 0.0 4.6e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_L21p PF00829.16 KOS20438.1 - 0.0017 18.4 0.0 0.0021 18.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein FAP PF07174.6 KOS20438.1 - 0.0026 17.1 8.0 0.0029 16.9 5.5 1.2 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) Pkinase PF00069.20 KOS20439.1 - 9.8e-47 159.2 0.0 1.5e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS20439.1 - 6e-20 71.3 0.0 8.7e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS20439.1 - 7.1e-05 21.9 0.0 0.00069 18.6 0.0 2.1 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 KOS20439.1 - 0.00016 21.4 0.7 1.5 8.5 0.0 3.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 KOS20439.1 - 0.022 14.1 0.2 0.087 12.1 0.1 2.0 1 1 1 2 2 2 0 RIO1 family Ribosomal_S8e PF01201.17 KOS20440.1 - 1.6e-32 112.3 5.2 5.5e-32 110.6 3.6 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e ERCC4 PF02732.10 KOS20441.1 - 3.2e-31 107.9 0.2 5.7e-31 107.2 0.1 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 KOS20441.1 - 0.004 17.3 0.0 0.013 15.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain PGM_PMM_I PF02878.11 KOS20442.1 - 2e-18 66.1 0.8 5.5e-09 35.6 0.0 3.1 2 1 2 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KOS20442.1 - 4.9e-14 52.5 0.0 2.1e-13 50.5 0.0 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KOS20442.1 - 1.1e-08 34.9 0.2 4.3e-08 33.0 0.1 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KOS20442.1 - 0.032 14.2 0.0 0.084 12.9 0.0 1.8 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PhoD PF09423.5 KOS20443.1 - 1.3e-06 27.2 0.0 2.7e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase TMEM101 PF15111.1 KOS20444.1 - 0.022 14.0 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 TMEM101 protein family DUF4436 PF14494.1 KOS20444.1 - 0.047 12.9 0.1 0.069 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) DUF4381 PF14316.1 KOS20444.1 - 0.078 13.0 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Shisa PF13908.1 KOS20444.1 - 0.11 12.6 0.4 0.14 12.3 0.2 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 KOS20444.1 - 0.12 10.6 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4079 PF13301.1 KOS20444.1 - 0.12 12.3 0.1 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) HAMP PF00672.20 KOS20444.1 - 0.38 10.9 3.8 0.16 12.1 1.1 1.5 2 0 0 2 2 2 0 HAMP domain Rhodanese PF00581.15 KOS20445.1 - 1.2e-13 51.3 0.0 1.5e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain HD_3 PF13023.1 KOS20447.1 - 1e-33 116.4 0.0 1.2e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.2 KOS20447.1 - 0.0068 16.2 0.0 0.0087 15.8 0.0 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.17 KOS20447.1 - 0.0097 15.9 0.2 0.033 14.1 0.0 1.9 2 1 0 2 2 2 1 HD domain Erg28 PF03694.8 KOS20448.1 - 4.7e-40 136.0 0.1 5.7e-40 135.7 0.0 1.1 1 0 0 1 1 1 1 Erg28 like protein adh_short PF00106.20 KOS20449.1 - 1.5e-21 77.0 0.1 2.3e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS20449.1 - 2.2e-10 40.7 0.0 3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS20449.1 - 5.3e-05 22.9 0.1 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KOS20449.1 - 0.0076 16.2 0.2 0.039 13.9 0.1 2.2 1 1 1 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KOS20449.1 - 0.019 13.8 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KOS20449.1 - 0.032 13.2 0.0 0.062 12.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase SWIRM PF04433.12 KOS20450.1 - 2.1e-13 50.1 0.0 7.9e-13 48.3 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 KOS20450.1 - 3e-10 39.4 3.8 5.3e-10 38.6 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 KOS20450.1 - 8.3e-07 28.9 0.0 4.1e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain GalP_UDP_transf PF01087.17 KOS20451.1 - 1.9e-68 230.1 0.1 7.1e-67 225.0 0.0 2.2 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KOS20451.1 - 8.7e-51 171.7 0.0 1.8e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 KOS20451.1 - 0.002 18.5 0.0 0.0053 17.2 0.0 1.7 1 0 0 1 1 1 1 HIT domain Nucleoporin_C PF03177.9 KOS20452.1 - 7.1e-125 417.7 3.5 9e-125 417.4 2.4 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KOS20452.1 - 3.8e-86 289.4 0.1 6.1e-86 288.7 0.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Sugar_tr PF00083.19 KOS20454.1 - 3.4e-25 88.5 9.1 8.9e-24 83.8 4.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KOS20454.1 - 2.2e-14 52.9 11.9 3.6e-14 52.2 8.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_1 PF00561.15 KOS20455.1 - 1.6e-39 135.8 0.0 4.4e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KOS20455.1 - 2.1e-12 47.3 2.5 4.8e-11 42.9 1.7 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Mucin PF01456.12 KOS20455.1 - 0.11 12.2 15.4 0.22 11.3 10.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 KOS20455.1 - 0.3 10.8 10.7 0.63 9.7 7.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 KOS20455.1 - 3.5 5.4 16.3 4.7 5.0 11.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF221 PF02714.10 KOS20456.1 - 7.6e-99 330.6 22.2 7.6e-99 330.6 15.4 2.5 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KOS20456.1 - 2.2e-37 128.0 5.5 6.5e-37 126.5 2.7 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KOS20456.1 - 2.5e-24 84.9 0.0 3.6e-23 81.2 0.0 2.3 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 KOS20456.1 - 1.5e-19 70.3 0.0 2.3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_1 PF00076.17 KOS20456.1 - 0.17 11.5 0.3 0.95 9.1 0.1 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SKG6 PF08693.5 KOS20457.1 - 2.5e-06 26.7 0.0 6.4e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4381 PF14316.1 KOS20457.1 - 0.002 18.2 0.1 0.0044 17.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF4448 PF14610.1 KOS20457.1 - 0.0051 16.3 0.0 0.034 13.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Kelch_4 PF13418.1 KOS20457.1 - 0.04 13.6 12.8 2.1 8.1 0.1 5.1 4 1 0 4 4 4 0 Galactose oxidase, central domain Methyltransf_31 PF13847.1 KOS20459.1 - 1.3e-12 47.5 0.1 2.2e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KOS20459.1 - 4.2e-11 42.5 0.0 7.1e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 KOS20459.1 - 8.4e-10 38.1 0.1 1.2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 KOS20459.1 - 8.7e-10 39.1 0.0 1.8e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS20459.1 - 2e-09 37.5 0.0 4.3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS20459.1 - 4.8e-08 33.3 0.0 1.1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KOS20459.1 - 3.6e-07 29.1 0.1 5.4e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 KOS20459.1 - 2.6e-06 27.7 0.1 2.7e-05 24.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS20459.1 - 5.2e-06 26.2 0.0 9.4e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS20459.1 - 6e-06 25.7 0.2 1.5e-05 24.4 0.1 1.7 1 1 1 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 KOS20459.1 - 0.00015 21.8 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 KOS20459.1 - 0.00019 21.8 0.0 0.00036 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KOS20459.1 - 0.00037 19.6 0.0 0.00051 19.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.11 KOS20459.1 - 0.0013 18.3 0.1 0.0021 17.6 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.14 KOS20459.1 - 0.008 15.7 0.2 0.013 15.0 0.2 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KOS20459.1 - 0.0086 15.7 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KOS20459.1 - 0.0094 15.5 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_16 PF10294.4 KOS20459.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 KOS20459.1 - 0.028 13.5 1.3 0.072 12.2 0.1 2.2 2 2 1 3 3 3 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 KOS20459.1 - 0.039 13.0 0.0 0.069 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.8 KOS20459.1 - 0.068 12.4 0.4 0.17 11.1 0.2 1.7 1 1 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.15 KOS20459.1 - 0.074 12.0 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.10 KOS20459.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF1765 PF08578.5 KOS20460.1 - 1.3e-44 151.3 2.2 2.9e-44 150.1 1.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) PA-IIL PF07472.6 KOS20460.1 - 0.087 13.0 0.1 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Fucose-binding lectin II (PA-IIL) Mmp37 PF09139.6 KOS20461.1 - 2.2e-116 388.4 0.0 2.9e-116 388.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 MAD PF05557.8 KOS20462.1 - 2.3e-46 158.2 57.4 4.1e-46 157.4 39.8 1.3 1 1 0 1 1 1 1 Mitotic checkpoint protein Leu_zip PF15294.1 KOS20462.1 - 0.0019 17.3 15.6 0.0019 17.3 10.8 5.9 2 2 3 5 5 5 3 Leucine zipper Hydantoinase_B PF02538.9 KOS20462.1 - 0.52 8.4 1.5 0.91 7.6 0.8 1.5 1 1 0 1 1 1 0 Hydantoinase B/oxoprolinase muHD PF10291.4 KOS20463.1 - 3.3e-55 187.0 0.0 1.1e-54 185.2 0.0 1.8 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain FCH PF00611.18 KOS20463.1 - 7.9e-11 42.0 0.0 2.3e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain BAR PF03114.13 KOS20463.1 - 0.00013 21.5 3.4 0.00022 20.8 2.4 1.2 1 0 0 1 1 1 1 BAR domain PAS_10 PF13596.1 KOS20463.1 - 0.015 15.5 0.2 0.046 13.9 0.2 1.8 1 0 0 1 1 1 0 PAS domain FAM92 PF06730.6 KOS20463.1 - 0.068 12.4 3.4 0.13 11.6 2.4 1.3 1 0 0 1 1 1 0 FAM92 protein Vps5 PF09325.5 KOS20463.1 - 0.1 11.8 6.8 0.2 10.8 4.7 1.5 1 0 0 1 1 1 0 Vps5 C terminal like LRR_4 PF12799.2 KOS20465.1 - 0.012 15.2 0.1 0.62 9.7 0.0 3.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KOS20465.1 - 0.12 12.5 1.2 1.2e+02 3.2 0.0 4.9 6 0 0 6 6 6 0 Leucine Rich repeat Dicty_REP PF05086.7 KOS20465.1 - 0.83 7.3 7.7 1.2 6.7 5.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FLO_LFY PF01698.11 KOS20465.1 - 2.5 6.8 8.6 4.4 6.0 5.9 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein TPR_8 PF13181.1 KOS20466.1 - 0.097 12.4 1.6 69 3.5 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF966 PF06136.8 KOS20467.1 - 0.11 11.8 2.0 0.11 11.8 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PRA-CH PF01502.13 KOS20467.1 - 0.12 11.9 0.2 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase Nop14 PF04147.7 KOS20468.1 - 1.5 6.6 38.3 0.12 10.3 18.8 2.0 2 0 0 2 2 2 0 Nop14-like family Defensin_propep PF00879.13 KOS20468.1 - 1.9 8.5 0.0 1.9 8.5 0.0 3.1 2 1 1 3 3 3 0 Defensin propeptide Ribosomal_L1 PF00687.16 KOS20469.1 - 5.1e-54 182.9 0.0 6.9e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Palm_thioest PF02089.10 KOS20470.1 - 3.4e-53 180.4 0.0 4.4e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase HAD_2 PF13419.1 KOS20471.1 - 2.7e-16 60.2 0.0 9.6e-15 55.2 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KOS20471.1 - 0.00048 19.7 0.0 0.00082 19.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like zf-MIZ PF02891.15 KOS20472.1 - 5.1e-10 38.7 1.0 1.2e-09 37.5 0.7 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KOS20472.1 - 0.024 14.1 0.5 0.059 12.9 0.3 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ribosomal_S21 PF01165.15 KOS20473.1 - 4.2e-07 29.2 11.9 6.9e-07 28.6 8.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 PWI PF01480.12 KOS20474.1 - 2.8e-09 36.9 0.0 6.5e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 PWI domain Polysacc_deac_1 PF01522.16 KOS20475.1 - 3.7e-29 100.8 0.0 5.9e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 KOS20475.1 - 8.9e-13 47.9 44.1 1.8e-06 27.7 11.6 2.5 2 0 0 2 2 2 2 Chitin recognition protein Coatomer_WDAD PF04053.9 KOS20476.1 - 2.1e-167 557.4 0.0 4.1e-167 556.4 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 KOS20476.1 - 6.7e-48 158.9 8.5 2e-10 40.1 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 KOS20476.1 - 5.1e-05 21.6 3.1 0.0068 14.5 0.0 3.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KOS20476.1 - 0.0055 16.4 0.0 5.7 6.7 0.0 3.3 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Sugar_tr PF00083.19 KOS20477.1 - 2e-31 109.0 34.4 9e-20 70.6 8.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KOS20477.1 - 7.3e-20 70.9 40.4 4.9e-10 38.6 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.8 KOS20477.1 - 0.82 9.7 0.0 0.82 9.7 0.0 4.4 4 0 0 4 4 4 0 Transglycosylase associated protein Glyco_hydro_3 PF00933.16 KOS20478.1 - 1.3e-84 283.7 0.0 2.4e-84 282.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KOS20478.1 - 3.7e-56 190.1 0.1 6.7e-56 189.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KOS20478.1 - 2.5e-21 75.4 0.0 4.7e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Mannitol_dh_C PF08125.8 KOS20479.1 - 6.4e-46 156.5 0.1 1e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KOS20479.1 - 6e-18 65.2 0.3 1.9e-17 63.6 0.0 1.9 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 KOS20479.1 - 9.2e-05 21.9 0.7 0.00025 20.4 0.2 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HAUS6_N PF14661.1 KOS20480.1 - 3.8e-50 170.5 1.9 5.9e-50 169.9 0.4 1.9 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus DUF1768 PF08719.6 KOS20480.1 - 0.011 15.4 0.4 0.021 14.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) Zip PF02535.17 KOS20480.1 - 3.1 6.7 4.6 6.7 5.6 3.2 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.20 KOS20481.1 - 6.5e-70 235.2 0.0 9.2e-70 234.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS20481.1 - 1.1e-31 109.8 0.0 1.6e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KOS20481.1 - 1.3e-10 41.6 2.4 3.2e-10 40.3 1.6 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KOS20481.1 - 0.00022 20.2 0.0 0.00037 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KOS20481.1 - 0.078 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KOS20481.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PGI PF00342.14 KOS20482.1 - 2.8e-207 688.9 0.0 3.2e-207 688.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF1681 PF07933.9 KOS20483.1 - 8.4e-51 171.7 0.0 1.1e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) GCR1_C PF12550.3 KOS20483.1 - 0.051 13.4 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes H_lectin PF09458.5 KOS20484.1 - 6.6e-17 60.9 0.0 1.3e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 H-type lectin domain NPV_P10 PF05531.7 KOS20484.1 - 5e-06 26.6 17.7 0.014 15.6 3.6 4.7 1 1 3 4 4 4 2 Nucleopolyhedrovirus P10 protein FlxA PF14282.1 KOS20484.1 - 1.3e-05 25.0 19.5 0.0043 16.9 1.1 4.3 1 1 2 3 3 3 1 FlxA-like protein CENP-F_leu_zip PF10473.4 KOS20484.1 - 8e-05 22.5 4.4 0.00011 22.1 1.2 2.3 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 KOS20484.1 - 0.00011 22.1 4.4 0.0041 17.1 1.3 2.5 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Myosin_tail_1 PF01576.14 KOS20484.1 - 0.0002 19.2 3.0 0.00028 18.7 2.1 1.2 1 0 0 1 1 1 1 Myosin tail MscS_porin PF12795.2 KOS20484.1 - 0.00042 19.6 15.6 0.00042 19.6 10.8 1.5 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 KOS20484.1 - 0.00054 18.5 3.6 0.00072 18.1 2.5 1.1 1 0 0 1 1 1 1 AAA domain Laminin_II PF06009.7 KOS20484.1 - 0.00054 19.7 9.0 0.0007 19.3 0.4 2.7 1 1 1 2 2 2 2 Laminin Domain II DUF2730 PF10805.3 KOS20484.1 - 0.00056 19.6 3.1 0.003 17.2 0.1 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF2730) Tropomyosin_1 PF12718.2 KOS20484.1 - 0.00076 19.3 2.7 0.0078 16.0 0.0 2.5 1 1 1 2 2 2 1 Tropomyosin like Reo_sigmaC PF04582.7 KOS20484.1 - 0.0013 17.9 0.6 0.0013 17.9 0.4 2.2 1 1 1 2 2 2 1 Reovirus sigma C capsid protein IncA PF04156.9 KOS20484.1 - 0.0019 17.7 14.1 0.071 12.7 9.7 2.5 1 1 0 1 1 1 1 IncA protein CCDC155 PF14662.1 KOS20484.1 - 0.0024 17.5 9.1 0.0036 16.9 6.3 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 TBPIP PF07106.8 KOS20484.1 - 0.0035 16.9 4.0 0.04 13.4 0.2 2.6 1 1 1 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 KOS20484.1 - 0.0051 16.5 9.5 0.38 10.4 0.9 2.4 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.6 KOS20484.1 - 0.006 16.4 1.7 1.2 9.0 0.0 3.3 3 1 1 4 4 2 1 Flagella accessory protein C (FlaC) IFT57 PF10498.4 KOS20484.1 - 0.0071 15.1 1.0 0.01 14.6 0.7 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF2968 PF11180.3 KOS20484.1 - 0.0084 15.5 8.6 0.0084 15.5 6.0 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2968) Lzipper-MIP1 PF14389.1 KOS20484.1 - 0.0094 16.0 3.1 0.0094 16.0 2.2 3.1 1 1 2 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 AAA_27 PF13514.1 KOS20484.1 - 0.014 13.1 11.7 0.019 12.6 8.1 1.1 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 KOS20484.1 - 0.017 15.2 0.1 0.017 15.2 0.1 3.2 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.3 KOS20484.1 - 0.021 12.1 8.7 0.028 11.7 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.7 KOS20484.1 - 0.021 14.6 4.5 0.56 10.0 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.3 KOS20484.1 - 0.03 14.2 8.5 1.2 9.0 0.5 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Tropomyosin PF00261.15 KOS20484.1 - 0.038 13.0 1.7 0.077 12.0 0.9 1.7 1 1 0 1 1 1 0 Tropomyosin Cast PF10174.4 KOS20484.1 - 0.051 11.6 5.6 0.068 11.2 3.9 1.2 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone V_ATPase_I PF01496.14 KOS20484.1 - 0.076 10.8 0.3 0.11 10.3 0.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 KOS20484.1 - 0.08 11.5 4.4 0.083 11.5 1.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.6 KOS20484.1 - 0.083 12.7 7.9 0.36 10.6 5.5 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Prefoldin_2 PF01920.15 KOS20484.1 - 0.1 12.3 6.4 7.6 6.3 2.2 2.9 1 1 1 2 2 2 0 Prefoldin subunit RTBV_P46 PF06216.6 KOS20484.1 - 0.12 11.1 0.2 5.6 5.7 0.0 2.1 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein DUF4407 PF14362.1 KOS20484.1 - 0.19 10.6 8.9 0.16 10.9 4.8 1.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) GP41 PF00517.12 KOS20484.1 - 0.28 10.7 12.2 3 7.3 0.1 3.5 1 1 2 3 3 3 0 Retroviral envelope protein DUF972 PF06156.8 KOS20484.1 - 0.29 11.5 5.1 1.2 9.4 0.1 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 KOS20484.1 - 0.31 10.8 6.2 0.94 9.3 0.8 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 KOS20484.1 - 0.34 9.9 3.5 0.7 8.8 0.1 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Macoilin PF09726.4 KOS20484.1 - 0.37 9.0 11.4 1.2 7.2 7.9 1.7 1 1 0 1 1 1 0 Transmembrane protein DUF812 PF05667.6 KOS20484.1 - 0.41 9.0 9.0 0.55 8.6 5.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF812) End3 PF12761.2 KOS20484.1 - 0.42 10.2 4.0 0.22 11.1 0.5 1.9 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF16 PF01519.11 KOS20484.1 - 0.47 10.7 5.8 84 3.4 4.0 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 Cortex-I_coil PF09304.5 KOS20484.1 - 0.49 10.4 5.3 2.6 8.1 0.1 2.7 1 1 0 2 2 2 0 Cortexillin I, coiled coil Filament PF00038.16 KOS20484.1 - 0.58 9.5 7.9 12 5.2 5.3 2.3 1 1 1 2 2 2 0 Intermediate filament protein Cob_adeno_trans PF01923.13 KOS20484.1 - 0.72 9.6 6.4 1.1 9.0 0.5 2.4 1 1 1 2 2 2 0 Cobalamin adenosyltransferase HlyD PF00529.15 KOS20484.1 - 0.84 8.8 23.1 1 8.5 14.9 1.7 1 1 1 2 2 2 0 HlyD family secretion protein DUF3450 PF11932.3 KOS20484.1 - 0.93 8.7 15.9 0.059 12.6 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4140 PF13600.1 KOS20484.1 - 1.5 9.2 15.4 4.8e+02 1.2 0.1 3.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.7 KOS20484.1 - 1.6 9.1 21.1 2 8.8 1.9 4.9 1 1 2 4 4 4 0 SlyX FliD_N PF02465.13 KOS20484.1 - 1.9 8.9 8.4 3.4 8.0 0.3 3.8 2 1 2 4 4 4 0 Flagellar hook-associated protein 2 N-terminus Nsp1_C PF05064.8 KOS20484.1 - 2.4 7.8 7.4 0.68 9.5 0.6 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region HrpB7 PF09486.5 KOS20484.1 - 3.1 7.6 17.0 5 7.0 0.0 3.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Syntaxin-6_N PF09177.6 KOS20484.1 - 4.6 7.7 5.4 12 6.3 0.4 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fib_alpha PF08702.5 KOS20484.1 - 5.6 7.0 5.6 27 4.8 0.6 2.7 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 KOS20484.1 - 9.8 5.7 12.1 4.4 6.8 1.0 4.0 1 1 3 4 4 4 0 Septum formation initiator NPV_P10 PF05531.7 KOS20485.1 - 3.5e-05 23.9 17.3 0.091 13.0 1.8 4.0 1 1 4 5 5 5 5 Nucleopolyhedrovirus P10 protein FliH PF02108.11 KOS20485.1 - 3.8e-05 23.5 4.9 0.46 10.3 0.1 3.9 1 1 1 2 2 2 2 Flagellar assembly protein FliH DUF2681 PF10883.3 KOS20485.1 - 8.1e-05 22.7 16.5 0.0096 16.1 0.2 4.1 1 1 3 4 4 4 1 Protein of unknown function (DUF2681) Viral_cys_rich PF08008.7 KOS20485.1 - 0.0016 17.9 6.4 7.4 6.2 0.0 4.3 1 1 3 4 4 4 0 Viral cysteine rich EcoEI_R_C PF08463.5 KOS20485.1 - 0.0025 17.6 17.7 0.081 12.7 5.0 2.5 1 1 1 2 2 2 2 EcoEI R protein C-terminal Herpes_UL47 PF03362.8 KOS20485.1 - 0.0074 14.6 0.7 0.22 9.8 0.1 2.1 1 1 1 2 2 2 1 Herpesvirus UL47 protein DUF3417 PF11897.3 KOS20485.1 - 0.0078 16.1 10.5 0.3 11.0 2.5 2.9 1 1 2 3 3 3 2 Protein of unknown function (DUF3417) PG_binding_1 PF01471.13 KOS20485.1 - 0.0084 16.0 10.6 11 6.0 0.2 4.5 1 1 3 4 4 4 0 Putative peptidoglycan binding domain PspB PF06667.7 KOS20485.1 - 0.011 15.6 18.9 7.3 6.6 0.2 5.5 2 1 3 6 6 5 0 Phage shock protein B Phage_GP20 PF06810.6 KOS20485.1 - 0.034 13.5 24.0 0.022 14.2 4.2 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 MAAL_C PF07476.6 KOS20485.1 - 0.045 12.6 2.7 0.73 8.7 0.2 2.2 1 1 2 3 3 3 0 Methylaspartate ammonia-lyase C-terminus DUF885 PF05960.6 KOS20485.1 - 0.054 12.6 6.0 0.068 12.3 4.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) OTCace_N PF02729.16 KOS20485.1 - 0.055 13.1 3.5 2 8.0 0.2 2.6 1 1 3 4 4 4 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF3086 PF11285.3 KOS20485.1 - 0.068 11.9 14.4 0.85 8.3 5.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) AcetDehyd-dimer PF09290.6 KOS20485.1 - 0.072 12.9 6.3 18 5.2 0.0 3.9 1 1 3 4 4 4 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Prominin PF05478.6 KOS20485.1 - 0.095 10.2 16.1 0.1 10.1 4.4 2.0 1 1 1 2 2 2 0 Prominin Matrilin_ccoil PF10393.4 KOS20485.1 - 0.17 11.3 25.2 3.2 7.2 0.3 6.3 1 1 5 6 6 6 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4172 PF13776.1 KOS20485.1 - 0.2 11.7 9.2 2.7 8.1 0.4 3.3 1 1 2 4 4 4 0 Domain of unknown function (DUF4172) Telomere_reg-2 PF10193.4 KOS20485.1 - 0.23 11.7 8.6 1.5 9.1 3.5 2.4 1 1 1 2 2 2 0 Telomere length regulation protein IncA PF04156.9 KOS20485.1 - 0.31 10.6 24.2 2.5 7.6 16.8 2.0 1 1 0 1 1 1 0 IncA protein PilJ PF13675.1 KOS20485.1 - 0.39 11.0 14.8 2.6 8.3 4.6 2.6 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term GP41 PF00517.12 KOS20485.1 - 0.41 10.1 10.6 3.4 7.1 1.2 3.0 1 1 0 2 2 2 0 Retroviral envelope protein DUF3732 PF12532.3 KOS20485.1 - 0.5 9.8 12.3 2.1 7.8 1.1 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3732) DIL PF01843.14 KOS20485.1 - 0.52 10.2 6.4 11 5.9 1.0 3.1 1 1 3 4 4 4 0 DIL domain Toxin_52 PF15605.1 KOS20485.1 - 0.55 10.1 9.9 7.7 6.4 0.2 3.1 1 1 0 2 2 2 0 Putative toxin 52 Syntaxin PF00804.20 KOS20485.1 - 0.55 10.4 21.0 0.45 10.7 5.9 2.9 1 1 3 4 4 4 0 Syntaxin Syntaxin_2 PF14523.1 KOS20485.1 - 0.97 9.4 19.8 3 7.9 1.1 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Baculo_p33 PF05214.7 KOS20485.1 - 0.99 8.6 3.4 7.2 5.8 0.3 2.1 1 1 1 2 2 2 0 Baculovirus P33 DUF1664 PF07889.7 KOS20485.1 - 1.1 9.0 14.3 1.1 9.0 1.1 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2797 PF10977.3 KOS20485.1 - 1.4 8.5 11.9 1.8 8.1 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2797) H-kinase_dim PF02895.9 KOS20485.1 - 1.5 9.2 22.2 1.5e+04 -5.8 15.4 4.4 1 1 0 1 1 0 0 Signal transducing histidine kinase, homodimeric domain Mnd1 PF03962.10 KOS20485.1 - 1.9 8.1 22.1 0.76 9.4 4.1 2.2 1 1 1 2 2 2 0 Mnd1 family Val_tRNA-synt_C PF10458.4 KOS20485.1 - 2 8.5 14.3 7.8 6.6 0.5 4.5 1 1 4 5 5 5 0 Valyl tRNA synthetase tRNA binding arm Syntaxin-6_N PF09177.6 KOS20485.1 - 2.1 8.8 17.5 1.3 9.5 1.9 3.1 1 1 2 3 3 3 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 KOS20485.1 - 2.2 8.2 5.7 5 7.1 0.2 3.6 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Holin_LLH PF09682.5 KOS20485.1 - 2.4 8.3 5.5 5.9 7.0 1.5 2.2 1 1 1 2 2 2 0 Phage holin protein (Holin_LLH) Trigger_N PF05697.8 KOS20485.1 - 2.9 7.7 10.4 15 5.3 0.3 4.0 1 1 4 5 5 5 0 Bacterial trigger factor protein (TF) DUF948 PF06103.6 KOS20485.1 - 3.1 7.7 19.2 7.8 6.4 4.6 3.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) D5_N PF08706.6 KOS20485.1 - 3.4 7.7 6.1 1.2e+02 2.7 4.2 2.4 1 1 0 1 1 1 0 D5 N terminal like GAT PF03127.9 KOS20485.1 - 3.5 7.6 12.5 12 5.9 1.6 2.4 1 1 1 2 2 2 0 GAT domain Noc2 PF03715.8 KOS20485.1 - 4 6.2 9.2 3 6.5 1.3 2.2 1 1 0 2 2 2 0 Noc2p family CorA PF01544.13 KOS20485.1 - 4.2 6.2 9.5 9.5 5.1 6.5 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein HsdM_N PF12161.3 KOS20485.1 - 4.3 7.7 8.5 1.4e+02 2.8 5.8 2.5 1 1 0 1 1 1 0 HsdM N-terminal domain FBP PF07299.6 KOS20485.1 - 4.5 6.5 9.6 6.4 6.0 1.5 2.4 1 1 1 2 2 2 0 Fibronectin-binding protein (FBP) ANTAR PF03861.9 KOS20485.1 - 4.7 6.8 11.3 4.9 6.8 2.0 3.3 1 1 2 3 3 3 0 ANTAR domain U3snoRNP10 PF12397.3 KOS20485.1 - 5.4 6.9 6.9 9.9 6.1 2.2 2.5 1 1 1 2 2 2 0 U3 small nucleolar RNA-associated protein 10 bZIP_2 PF07716.10 KOS20485.1 - 5.7 6.8 20.2 8.2 6.3 0.1 5.1 5 0 0 5 5 5 0 Basic region leucine zipper Aida_N PF08910.5 KOS20485.1 - 5.8 7.1 9.5 26 5.1 0.8 2.5 1 1 1 2 2 2 0 Aida N-terminus ASL_C PF08328.6 KOS20485.1 - 6.2 6.7 9.1 9.8 6.0 0.8 2.6 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminal HisKA PF00512.20 KOS20485.1 - 8.4 6.4 12.6 3 7.8 1.0 3.2 1 1 3 4 4 4 0 His Kinase A (phospho-acceptor) domain ALMT PF11744.3 KOS20485.1 - 8.5 4.9 7.8 27 3.2 5.4 1.8 1 1 0 1 1 1 0 Aluminium activated malate transporter DUF3573 PF12097.3 KOS20485.1 - 9.9 4.6 13.0 3.8 6.0 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) PI-PLC-X PF00388.14 KOS20486.1 - 2.3e-11 43.3 0.0 4.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Solute_trans_a PF03619.11 KOS20487.1 - 3e-71 239.9 22.0 3.5e-71 239.7 15.2 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Gln-synt_C PF00120.19 KOS20488.1 - 1.5e-52 178.2 0.0 6.9e-51 172.8 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 KOS20488.1 - 5.4e-28 98.3 0.1 1.7e-27 96.7 0.0 1.9 2 1 0 2 2 2 1 Amidohydrolase p450 PF00067.17 KOS20489.1 - 3.3e-53 180.8 0.0 5e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IF-2B PF01008.12 KOS20490.1 - 6.8e-43 146.6 0.0 9e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 KOS20490.1 - 0.12 11.9 0.1 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Med3 PF11593.3 KOS20491.1 - 0.097 11.8 6.8 0.2 10.8 4.7 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Tropomyosin PF00261.15 KOS20492.1 - 2 7.4 6.5 0.43 9.6 1.6 1.8 2 0 0 2 2 2 0 Tropomyosin Molybdopterin PF00384.17 KOS20493.1 - 1.1e-73 248.4 0.0 1.1e-71 241.8 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 KOS20493.1 - 1.7e-19 69.4 0.3 5.9e-19 67.6 0.2 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 KOS20493.1 - 4.1e-18 64.3 0.1 1.1e-17 62.9 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 KOS20493.1 - 2.3e-14 53.2 0.0 6.2e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 KOS20493.1 - 1.7e-08 34.0 0.6 1.7e-08 34.0 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 KOS20493.1 - 0.00066 19.4 0.0 0.054 13.2 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF3579 PF12112.3 KOS20493.1 - 0.057 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) Fer4 PF00037.22 KOS20493.1 - 0.1 12.2 1.1 3.1 7.5 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.6 KOS20493.1 - 0.39 10.5 2.2 9.5 6.1 1.5 2.6 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_17 PF13534.1 KOS20493.1 - 2.9 8.3 6.0 0.33 11.3 0.7 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Cation_efflux PF01545.16 KOS20494.1 - 2e-25 89.4 6.0 2.7e-25 89.0 4.2 1.1 1 0 0 1 1 1 1 Cation efflux family DUF4045 PF13254.1 KOS20494.1 - 6.9 5.8 10.3 13 4.9 7.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4045) DMRL_synthase PF00885.14 KOS20495.1 - 7.6e-47 158.5 0.0 5.8e-45 152.4 0.0 2.0 1 1 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase TRP PF06011.7 KOS20496.1 - 8e-85 285.0 24.0 4.3e-84 282.6 16.6 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KOS20496.1 - 0.0002 21.3 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 ML-like domain RNase_T PF00929.19 KOS20497.1 - 1.1e-24 87.5 0.0 1.7e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Cofilin_ADF PF00241.15 KOS20498.1 - 4.9e-31 107.2 0.3 5.7e-31 107.0 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HET PF06985.6 KOS20499.1 - 1.8e-16 60.5 0.0 3.2e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MRP-S33 PF08293.6 KOS20500.1 - 3.9e-26 90.8 0.1 4.9e-26 90.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 IBR PF01485.16 KOS20501.1 - 3.3e-13 49.3 55.0 1.4e-06 28.0 10.4 4.7 3 2 1 4 4 4 3 IBR domain zf-RING_2 PF13639.1 KOS20501.1 - 0.0012 18.6 7.4 0.0012 18.6 5.1 4.5 3 1 1 4 4 4 1 Ring finger domain LamB_YcsF PF03746.11 KOS20501.1 - 0.053 12.6 0.2 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 LamB/YcsF family Beta-lactamase PF00144.19 KOS20503.1 - 8.2e-52 176.2 1.4 9.1e-52 176.1 0.4 1.5 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.3 KOS20503.1 - 1.7e-10 40.6 0.0 3.2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) CDC45 PF02724.9 KOS20503.1 - 5 5.0 6.1 6.9 4.5 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 KOS20503.1 - 9.1 5.9 8.7 14 5.3 6.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Uds1 PF15456.1 KOS20504.1 - 1.7e-36 124.9 9.5 1.7e-36 124.9 6.6 6.6 2 1 4 6 6 5 1 Up-regulated During Septation Reo_sigmaC PF04582.7 KOS20504.1 - 4.2e-07 29.4 15.7 4e-05 22.9 0.5 4.0 2 1 2 5 5 5 2 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 KOS20504.1 - 0.00014 21.6 9.6 0.00014 21.6 6.7 7.6 3 2 2 7 7 7 2 Tropomyosin like CENP-F_leu_zip PF10473.4 KOS20504.1 - 0.00015 21.6 4.2 0.00015 21.6 2.9 9.0 5 1 4 10 10 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.15 KOS20504.1 - 0.0022 17.1 10.3 0.0022 17.1 7.1 7.7 4 1 2 6 6 6 1 Tropomyosin IncA PF04156.9 KOS20504.1 - 0.0035 16.9 17.4 0.0035 16.9 12.0 6.5 2 1 4 6 6 5 3 IncA protein Cep57_CLD PF14073.1 KOS20504.1 - 0.0052 16.6 10.5 0.0052 16.6 7.3 5.3 3 2 0 4 4 3 1 Centrosome localisation domain of Cep57 TMF_DNA_bd PF12329.3 KOS20504.1 - 0.0056 16.4 3.4 0.0056 16.4 2.4 9.2 8 3 2 10 10 10 3 TATA element modulatory factor 1 DNA binding DUF16 PF01519.11 KOS20504.1 - 0.007 16.5 0.3 0.007 16.5 0.2 5.9 3 1 1 5 5 5 1 Protein of unknown function DUF16 Bcr-Abl_Oligo PF09036.5 KOS20504.1 - 0.24 11.3 0.1 0.24 11.3 0.0 6.0 5 1 2 7 7 7 0 Bcr-Abl oncoprotein oligomerisation domain AAA_13 PF13166.1 KOS20504.1 - 0.29 9.5 47.5 0.06 11.8 9.1 4.1 3 1 1 4 4 4 0 AAA domain Fib_alpha PF08702.5 KOS20504.1 - 8.6 6.4 34.1 1.2 9.2 0.3 6.7 2 2 2 6 6 6 0 Fibrinogen alpha/beta chain family Tcp11 PF05794.8 KOS20505.1 - 8e-84 281.8 0.2 1.5e-76 257.8 0.2 2.0 2 0 0 2 2 2 2 T-complex protein 11 TFIID-18kDa PF02269.11 KOS20506.1 - 2.1e-18 65.8 0.1 3.2e-18 65.3 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KOS20506.1 - 0.00011 21.7 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 KOS20506.1 - 0.00062 19.8 0.2 0.0019 18.2 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KOS20506.1 - 0.0031 17.5 0.7 0.041 13.9 0.0 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 KOS20506.1 - 0.036 14.2 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 Kinetochore component CENP-S TIP49 PF06068.8 KOS20507.1 - 6.8e-188 624.3 0.1 7.8e-188 624.1 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KOS20507.1 - 1.6e-10 41.2 0.2 8.6e-07 29.2 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KOS20507.1 - 2.9e-10 39.6 0.4 1.9e-06 27.1 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KOS20507.1 - 6e-05 22.7 0.1 0.00016 21.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KOS20507.1 - 0.00012 22.2 0.3 0.47 10.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KOS20507.1 - 0.0002 21.4 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.1 KOS20507.1 - 0.00061 19.7 0.1 0.0015 18.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KOS20507.1 - 0.0015 17.9 0.0 0.0074 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KOS20507.1 - 0.0034 17.1 0.1 0.11 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KOS20507.1 - 0.0046 16.0 0.3 0.015 14.4 0.2 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KOS20507.1 - 0.015 15.5 0.1 0.037 14.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KOS20507.1 - 0.017 14.5 1.4 0.022 14.1 0.1 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.4 KOS20507.1 - 0.02 13.9 0.1 0.074 12.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 KOS20507.1 - 0.025 14.0 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 KOS20507.1 - 0.028 13.5 0.1 0.76 8.8 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.10 KOS20507.1 - 0.029 13.2 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain MinE PF03776.9 KOS20507.1 - 0.078 12.4 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE AAA_17 PF13207.1 KOS20507.1 - 0.082 13.7 0.1 0.21 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain SecE PF00584.15 KOS20509.1 - 0.02 14.4 1.1 0.034 13.7 0.8 1.4 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex TMEM219 PF14940.1 KOS20509.1 - 0.025 13.6 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane 219 Flavi_M PF01004.14 KOS20509.1 - 0.037 13.4 0.3 0.055 12.8 0.2 1.5 1 1 0 1 1 1 0 Flavivirus envelope glycoprotein M UPF0542 PF15086.1 KOS20509.1 - 0.043 13.5 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF2910 PF11139.3 KOS20509.1 - 0.049 12.7 0.9 0.056 12.5 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) SieB PF14163.1 KOS20509.1 - 0.13 11.7 1.0 0.62 9.6 0.4 1.8 2 0 0 2 2 2 0 Superinfection exclusion protein B PDR_CDR PF06422.7 KOS20509.1 - 0.15 11.7 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 CDR ABC transporter PMP1_2 PF08114.6 KOS20509.1 - 0.21 11.0 6.9 0.053 13.0 2.2 1.8 1 1 1 2 2 2 0 ATPase proteolipid family Tad PF13400.1 KOS20509.1 - 0.29 11.2 2.4 0.26 11.3 0.8 1.5 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DUF1469 PF07332.6 KOS20509.1 - 0.6 9.8 3.5 0.8 9.4 2.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) Sec61_beta PF03911.11 KOS20509.1 - 2.2 8.1 6.0 2.7 7.8 4.2 1.2 1 0 0 1 1 1 0 Sec61beta family Abhydrolase_6 PF12697.2 KOS20510.1 - 6.1e-07 29.5 3.1 9.3e-07 28.9 2.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KOS20510.1 - 0.00026 20.3 0.0 0.00049 19.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KOS20510.1 - 0.0094 15.5 0.6 0.079 12.5 0.4 2.0 1 1 0 1 1 1 1 PGAP1-like protein Arrestin_N PF00339.24 KOS20511.1 - 8.4e-13 48.3 0.0 2.1e-07 30.8 0.0 3.2 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 KOS20511.1 - 0.072 12.2 0.0 0.18 10.9 0.0 1.6 2 0 0 2 2 2 0 Bul1 C terminus DUF2360 PF10152.4 KOS20511.1 - 8.7 6.6 9.5 7.5 6.8 5.0 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) SAM_2 PF07647.12 KOS20513.1 - 2.5e-13 49.6 0.0 5.2e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 KOS20513.1 - 6.6e-12 44.6 0.0 1.5e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KOS20513.1 - 1.5e-11 43.7 0.0 3e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KOS20513.1 - 6.9e-10 39.0 0.0 5.3e-09 36.2 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KOS20513.1 - 6.8e-06 26.3 0.2 2.1e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 KOS20513.1 - 1.3e-05 24.6 0.0 4.2e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Agenet PF05641.7 KOS20513.1 - 0.1 12.7 0.0 0.36 11.0 0.0 2.0 1 0 0 1 1 1 0 Agenet domain Gastrin PF00918.12 KOS20513.1 - 1.5 9.6 0.0 1.5 9.6 0.0 3.7 4 0 0 4 4 4 0 Gastrin/cholecystokinin family Fork_head PF00250.13 KOS20514.1 - 1.3e-11 44.3 0.0 2.5e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KOS20514.1 - 0.00046 20.2 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain Ribosomal_60s PF00428.14 KOS20515.1 - 4.9 7.6 9.3 7.7 6.9 6.4 1.3 1 1 0 1 1 1 0 60s Acidic ribosomal protein ORC6 PF05460.8 KOS20517.1 - 0.11 11.6 4.9 0.13 11.3 3.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NnrS PF05940.7 KOS20518.1 - 0.054 12.3 0.1 0.068 12.0 0.1 1.1 1 0 0 1 1 1 0 NnrS protein Myb_DNA-bind_4 PF13837.1 KOS20518.1 - 0.065 13.3 0.0 6.5 6.9 0.0 3.1 2 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain GYF PF02213.11 KOS20519.1 - 2e-07 30.4 2.2 3.8e-07 29.5 1.5 1.5 1 0 0 1 1 1 1 GYF domain UFD1 PF03152.9 KOS20520.1 - 4.5e-65 218.0 0.0 5.5e-65 217.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Ribonuc_red_lgN PF00317.16 KOS20522.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.2 1 1 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain Ribosomal_60s PF00428.14 KOS20522.1 - 0.85 10.0 6.5 1.9 8.9 4.5 1.7 1 1 0 1 1 1 0 60s Acidic ribosomal protein PAT1 PF09770.4 KOS20523.1 - 1.2 7.3 19.2 1.3 7.1 13.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.14 KOS20524.1 - 0.0074 16.6 2.6 0.012 16.0 1.8 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein ORC6 PF05460.8 KOS20524.1 - 0.028 13.5 0.2 0.031 13.4 0.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pox_Ag35 PF03286.9 KOS20524.1 - 0.037 13.5 1.4 0.044 13.3 1.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CENP-N PF05238.8 KOS20524.1 - 0.051 12.6 0.2 0.055 12.5 0.2 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like BSP_II PF05432.6 KOS20524.1 - 0.22 10.7 4.3 0.3 10.3 3.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Blt1 PF12754.2 KOS20525.1 - 6.4e-36 124.5 0.4 2.8e-30 106.0 0.0 2.1 1 1 1 2 2 2 2 Cell-cycle control medial ring component ubiquitin PF00240.18 KOS20525.1 - 1.1e-06 27.9 0.0 1.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Cpn60_TCP1 PF00118.19 KOS20526.1 - 2e-118 396.0 8.7 2.3e-118 395.8 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.15 KOS20526.1 - 0.088 12.9 0.1 0.24 11.5 0.1 1.8 1 0 0 1 1 1 0 Transcriptional regulator XRCC4 PF06632.7 KOS20528.1 - 1.5e-08 33.9 0.7 2.1e-08 33.4 0.5 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Mito_fiss_reg PF05308.6 KOS20528.1 - 0.015 14.6 9.5 0.0093 15.3 3.3 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator ACBP PF00887.14 KOS20529.1 - 1.7e-30 104.5 0.0 3.1e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein PTPlike_phytase PF14566.1 KOS20530.1 - 0.0066 16.5 2.7 0.013 15.6 1.8 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Suf PF05843.9 KOS20530.1 - 0.095 12.4 3.5 0.14 11.8 2.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) APC_CDC26 PF10471.4 KOS20530.1 - 0.26 12.0 16.2 0.23 12.2 9.4 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Dicty_REP PF05086.7 KOS20530.1 - 0.38 8.4 1.3 1.7 6.3 1.9 1.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein BAF1_ABF1 PF04684.8 KOS20530.1 - 0.38 9.5 7.4 0.67 8.7 5.1 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDK5_activator PF03261.10 KOS20530.1 - 0.39 9.9 2.5 0.47 9.7 1.8 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4557 PF15101.1 KOS20530.1 - 0.63 9.8 7.1 0.64 9.8 4.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) APG6 PF04111.7 KOS20530.1 - 7 5.5 7.3 11 4.9 5.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Brix PF04427.13 KOS20531.1 - 5.7e-35 120.7 0.0 7.5e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Brix domain UPF0061 PF02696.9 KOS20532.1 - 1.1e-118 396.6 0.0 1.3e-118 396.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family MFS_1 PF07690.11 KOS20533.1 - 3.6e-27 94.9 16.9 5.6e-27 94.3 11.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4231 PF14015.1 KOS20533.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) DUF3405 PF11885.3 KOS20534.1 - 2e-186 620.1 2.2 3.9e-186 619.1 1.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) BCAS2 PF05700.6 KOS20536.1 - 1.7e-27 96.3 0.0 3e-27 95.5 0.0 1.3 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) cNMP_binding PF00027.24 KOS20537.1 - 1.7e-42 143.1 0.0 7.1e-21 73.8 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain GXGXG PF01493.14 KOS20537.1 - 0.12 11.3 0.0 0.31 10.0 0.0 1.6 2 0 0 2 2 2 0 GXGXG motif Transketolase_N PF00456.16 KOS20538.1 - 8.3e-150 498.1 0.0 1.1e-149 497.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KOS20538.1 - 3.5e-46 156.9 0.0 5.6e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KOS20538.1 - 5.1e-11 42.5 0.0 9.7e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KOS20538.1 - 0.00035 19.5 0.0 0.00091 18.2 0.0 1.5 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_N PF02776.13 KOS20538.1 - 0.034 13.6 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Glyco_hydro_20 PF00728.17 KOS20539.1 - 7.1e-83 278.6 0.0 8.8e-83 278.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Asp PF00026.18 KOS20539.1 - 1.3e-25 90.3 0.0 1.8e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Glycohydro_20b2 PF14845.1 KOS20539.1 - 7.4e-17 62.2 0.0 1.3e-16 61.4 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like TAXi_N PF14543.1 KOS20539.1 - 0.014 15.3 1.8 0.026 14.4 0.9 1.6 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal Glyco_hydro_20b PF02838.10 KOS20539.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 FUSC_2 PF13515.1 KOS20540.1 - 1.5e-22 79.8 5.4 1.5e-22 79.8 3.8 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 KOS20540.1 - 4.6e-09 35.2 2.4 4.6e-09 35.2 1.7 2.7 4 0 0 4 4 4 1 Fusaric acid resistance protein family ALMT PF11744.3 KOS20540.1 - 8.7e-05 21.3 3.9 8.7e-05 21.3 2.7 3.9 4 1 0 4 4 4 2 Aluminium activated malate transporter DUF2421 PF10334.4 KOS20540.1 - 0.025 14.1 0.0 0.075 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2421) DUF2422 PF10337.4 KOS20540.1 - 0.35 9.5 11.5 0.98 8.1 1.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2422) Peptidase_S8 PF00082.17 KOS20541.1 - 9.7e-16 57.7 0.0 2.1e-15 56.6 0.0 1.4 1 1 0 1 1 1 1 Subtilase family GHMP_kinases_N PF00288.21 KOS20541.1 - 0.013 15.5 0.7 0.04 13.9 0.4 1.8 2 0 0 2 2 2 0 GHMP kinases N terminal domain Ank PF00023.25 KOS20541.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.1 KOS20541.1 - 0.023 15.1 0.0 0.065 13.7 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS20541.1 - 0.024 14.8 0.0 0.24 11.7 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat MFS_1 PF07690.11 KOS20542.1 - 9.3e-23 80.4 58.4 5.1e-22 78.0 16.8 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily tRNA-synt_1d PF00750.14 KOS20543.1 - 6.5e-85 285.0 0.8 1.1e-84 284.2 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KOS20543.1 - 6.2e-27 93.9 0.2 1.5e-26 92.7 0.2 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KOS20543.1 - 0.0041 17.6 0.0 0.013 16.0 0.0 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Varsurf_PPLC PF03490.8 KOS20544.1 - 0.0077 15.8 0.3 0.019 14.6 0.2 1.7 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C TauD PF02668.11 KOS20546.1 - 1.9e-52 178.4 1.0 2.4e-52 178.1 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Methyltransf_23 PF13489.1 KOS20547.1 - 2.7e-17 62.9 0.0 4.3e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS20547.1 - 1.1e-13 51.7 0.0 1.7e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS20547.1 - 4.5e-13 49.0 0.0 7.3e-13 48.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS20547.1 - 9.5e-13 48.4 0.0 1.5e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS20547.1 - 9.6e-13 48.4 0.0 3.8e-12 46.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS20547.1 - 9.7e-11 41.9 0.0 1.5e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS20547.1 - 5.6e-10 39.2 0.4 1.6e-09 37.8 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KOS20547.1 - 6.7e-06 25.5 0.0 1.2e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_19 PF04672.7 KOS20547.1 - 1.3e-05 24.6 0.0 1.8e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl methyltransferase FtsJ PF01728.14 KOS20547.1 - 2.5e-05 24.3 0.0 3.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF938 PF06080.7 KOS20547.1 - 0.00012 21.7 0.0 0.00017 21.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.12 KOS20547.1 - 0.00034 19.7 0.0 0.00061 18.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_24 PF13578.1 KOS20547.1 - 0.00051 20.8 0.0 0.0029 18.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain TPMT PF05724.6 KOS20547.1 - 0.00092 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 KOS20547.1 - 0.0038 16.9 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KOS20547.1 - 0.0068 15.6 0.0 0.015 14.4 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 KOS20547.1 - 0.007 15.9 0.0 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 KOS20547.1 - 0.032 13.5 0.0 0.043 13.1 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.15 KOS20547.1 - 0.035 13.1 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CMAS PF02353.15 KOS20547.1 - 0.041 12.9 0.0 0.064 12.3 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase CheR PF01739.13 KOS20547.1 - 0.17 11.1 0.0 6 6.0 0.0 2.2 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain TehB PF03848.9 KOS20547.1 - 0.2 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Glyco_hydro_3 PF00933.16 KOS20548.1 - 1.5e-59 201.4 0.0 2.1e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DUF1212 PF06738.7 KOS20548.1 - 0.021 14.3 0.0 0.054 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Pmp3 PF01679.12 KOS20549.1 - 2e-19 69.0 5.5 2.7e-19 68.5 3.8 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Zip PF02535.17 KOS20549.1 - 0.024 13.6 0.6 0.033 13.2 0.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Med15 PF09606.5 KOS20549.1 - 4.2 5.4 28.5 4.9 5.2 19.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ank_2 PF12796.2 KOS20550.1 - 2.5e-31 107.8 0.2 5.3e-08 33.1 0.0 7.0 5 2 2 8 8 8 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KOS20550.1 - 6.2e-22 77.1 10.3 7.5e-08 32.3 0.3 7.5 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KOS20550.1 - 1.1e-17 64.0 3.4 0.00013 22.3 0.0 8.2 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.25 KOS20550.1 - 1.1e-16 59.6 15.6 0.00054 19.6 0.0 8.9 10 0 0 10 10 10 5 Ankyrin repeat Ank_3 PF13606.1 KOS20550.1 - 1.5e-15 55.7 8.4 0.4 11.0 0.0 10.5 12 0 0 12 12 12 5 Ankyrin repeat DUF3885 PF13021.1 KOS20550.1 - 0.0039 16.8 0.0 2.5 7.8 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3885) HA2 PF04408.18 KOS20551.1 - 2.6e-28 98.0 0.1 7.1e-28 96.6 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KOS20551.1 - 4.1e-27 94.2 0.0 1.7e-26 92.3 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KOS20551.1 - 1.3e-12 47.3 0.0 2.9e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KOS20551.1 - 4.4e-09 36.3 0.2 8.8e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KOS20551.1 - 4.6e-06 26.2 0.0 1.4e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KOS20551.1 - 1.2e-05 25.4 0.0 3.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KOS20551.1 - 1.2e-05 24.3 0.3 9.8e-05 21.3 0.0 2.4 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_30 PF13604.1 KOS20551.1 - 0.0016 18.0 0.1 0.067 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KOS20551.1 - 0.0027 17.4 0.1 0.01 15.5 0.1 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_14 PF13173.1 KOS20551.1 - 0.0049 16.7 0.1 0.064 13.1 0.1 2.5 2 1 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.1 KOS20551.1 - 0.014 15.4 0.0 0.077 13.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF1308 PF07000.6 KOS20551.1 - 0.017 13.7 0.1 0.032 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) ABC_tran PF00005.22 KOS20551.1 - 0.079 13.2 0.2 0.53 10.5 0.1 2.5 1 1 0 2 2 2 0 ABC transporter PhoH PF02562.11 KOS20551.1 - 0.079 12.1 0.1 0.33 10.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Myosin_head PF00063.16 KOS20551.1 - 0.14 10.2 0.0 0.21 9.5 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) DAP3 PF10236.4 KOS20551.1 - 0.19 10.6 0.0 0.5 9.2 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 KOS20551.1 - 0.24 10.2 0.0 0.4 9.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Herpes_ori_bp PF02399.10 KOS20551.1 - 0.51 8.2 0.0 0.81 7.5 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Spc97_Spc98 PF04130.8 KOS20552.1 - 6.6e-63 212.8 0.0 4.4e-43 147.4 0.0 2.1 2 0 0 2 2 2 2 Spc97 / Spc98 family Methyltransf_33 PF10017.4 KOS20554.1 - 1.2e-29 102.7 0.0 3.2e-29 101.4 0.0 1.8 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 KOS20554.1 - 2e-19 69.9 0.1 3.6e-18 65.8 0.1 2.4 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KOS20554.1 - 2e-06 28.1 1.6 8.1e-06 26.1 0.9 2.2 2 0 0 2 2 2 1 DinB superfamily Methyltransf_25 PF13649.1 KOS20554.1 - 0.095 13.0 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Senescence PF06911.7 KOS20555.1 - 1.2e-46 158.6 1.3 1.7e-46 158.1 0.9 1.2 1 0 0 1 1 1 1 Senescence-associated protein DEC-1_N PF04625.8 KOS20555.1 - 2.4 6.7 5.4 4 6.0 3.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Serglycin PF04360.7 KOS20555.1 - 5.5 6.7 8.5 5.6 6.6 3.5 2.2 2 0 0 2 2 2 0 Serglycin Arb1 PF09692.5 KOS20556.1 - 7.1e-76 255.5 0.0 9.2e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Glutaredoxin PF00462.19 KOS20557.1 - 1.8e-13 50.2 0.0 4e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Nop14 PF04147.7 KOS20557.1 - 2 6.2 10.7 2.7 5.7 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 KOS20557.1 - 2.7 6.9 5.0 0.52 9.2 0.3 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF2201_N PF13203.1 KOS20557.1 - 3.4 6.7 14.6 0.072 12.2 0.8 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain FLO_LFY PF01698.11 KOS20557.1 - 4.3 6.0 9.9 5.9 5.6 6.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein PBP1_TM PF14812.1 KOS20557.1 - 7.2 6.9 13.3 0.85 9.9 2.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PPP4R2 PF09184.6 KOS20557.1 - 9.4 5.6 13.4 3.3 7.1 0.2 2.1 2 0 0 2 2 2 0 PPP4R2 zf-MYND PF01753.13 KOS20559.1 - 9.8e-08 31.7 14.1 9.8e-08 31.7 9.7 2.1 2 0 0 2 2 2 1 MYND finger SET PF00856.23 KOS20559.1 - 2.3e-05 24.7 0.0 6.6e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 SET domain DUF4630 PF15443.1 KOS20559.1 - 2.6 7.8 8.4 0.38 10.5 1.3 2.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4630) DUF812 PF05667.6 KOS20560.1 - 1.9e-05 23.4 5.4 5.5e-05 21.8 3.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF812) DUF972 PF06156.8 KOS20560.1 - 3e-05 24.3 6.9 0.14 12.5 0.2 3.7 2 1 1 3 3 3 2 Protein of unknown function (DUF972) Rab5-bind PF09311.6 KOS20560.1 - 0.00016 21.5 5.3 0.00016 21.5 3.6 2.9 2 1 0 2 2 2 1 Rabaptin-like protein CENP-F_leu_zip PF10473.4 KOS20560.1 - 0.00042 20.1 12.8 0.062 13.1 0.6 3.6 3 1 0 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MAD PF05557.8 KOS20560.1 - 0.0009 17.4 8.7 0.0034 15.5 6.0 1.9 1 1 0 1 1 1 1 Mitotic checkpoint protein Reo_sigmaC PF04582.7 KOS20560.1 - 0.0015 17.7 3.4 0.084 12.0 0.1 2.8 2 1 0 3 3 3 1 Reovirus sigma C capsid protein DUF2353 PF09789.4 KOS20560.1 - 0.0045 16.2 8.0 0.014 14.6 5.3 1.9 2 1 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) IncA PF04156.9 KOS20560.1 - 0.0052 16.4 23.4 0.045 13.3 7.3 3.4 3 1 1 4 4 3 1 IncA protein GAS PF13851.1 KOS20560.1 - 0.0065 15.6 4.7 0.04 13.0 2.3 2.6 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding Y_phosphatase3 PF13350.1 KOS20560.1 - 0.0067 16.6 2.9 0.01 16.0 0.1 2.2 1 1 1 2 2 2 1 Tyrosine phosphatase family AAA_13 PF13166.1 KOS20560.1 - 0.0073 14.8 1.7 0.025 13.0 1.2 1.8 1 1 0 1 1 1 1 AAA domain CCDC155 PF14662.1 KOS20560.1 - 0.012 15.2 5.3 0.012 15.2 3.6 2.4 3 0 0 3 3 2 0 Coiled-coil region of CCDC155 Fez1 PF06818.10 KOS20560.1 - 0.012 15.6 8.6 0.012 15.6 5.9 2.6 2 1 1 3 3 2 0 Fez1 ATG16 PF08614.6 KOS20560.1 - 0.04 13.7 13.9 0.18 11.6 6.7 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 KOS20560.1 - 0.065 11.8 9.7 0.34 9.5 0.4 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein THOC7 PF05615.8 KOS20560.1 - 0.068 13.4 13.0 3.9 7.7 2.0 3.9 3 1 1 4 4 4 0 Tho complex subunit 7 PspA_IM30 PF04012.7 KOS20560.1 - 0.086 12.1 17.7 0.026 13.9 5.4 2.9 3 1 0 3 3 2 0 PspA/IM30 family Filament PF00038.16 KOS20560.1 - 0.097 12.1 17.5 0.064 12.7 4.6 3.0 2 1 1 3 3 3 0 Intermediate filament protein TBPIP PF07106.8 KOS20560.1 - 0.13 11.8 6.8 1.2 8.6 0.3 3.5 3 2 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Myosin_tail_1 PF01576.14 KOS20560.1 - 0.14 9.8 15.9 1.5 6.4 10.7 2.1 1 1 1 2 2 2 0 Myosin tail Fib_alpha PF08702.5 KOS20560.1 - 0.14 12.2 8.0 8.9 6.4 0.3 3.3 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 KOS20560.1 - 0.16 11.9 7.6 6.8 6.6 0.1 5.2 5 2 0 5 5 5 0 Flagella accessory protein C (FlaC) EzrA PF06160.7 KOS20560.1 - 0.32 9.1 9.9 5.8 4.9 0.7 2.7 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA Prominin PF05478.6 KOS20560.1 - 0.34 8.3 4.2 1.5 6.2 0.1 2.1 1 1 1 2 2 2 0 Prominin WEMBL PF05701.6 KOS20560.1 - 0.47 8.8 16.5 0.44 8.9 4.8 2.4 2 1 1 3 3 3 0 Weak chloroplast movement under blue light Atg14 PF10186.4 KOS20560.1 - 0.57 9.0 18.2 1.1 8.1 2.3 3.0 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2968 PF11180.3 KOS20560.1 - 0.92 8.8 26.9 1.1 8.6 4.9 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) Lectin_N PF03954.9 KOS20560.1 - 1.3 8.4 5.7 1.3 8.3 0.1 2.7 3 0 0 3 3 2 0 Hepatic lectin, N-terminal domain Tropomyosin_1 PF12718.2 KOS20560.1 - 2 8.2 9.4 0.46 10.3 1.0 3.2 3 0 0 3 3 3 0 Tropomyosin like Laminin_II PF06009.7 KOS20560.1 - 2 8.1 8.9 1.5 8.5 0.7 2.7 2 1 0 3 3 2 0 Laminin Domain II DUF4618 PF15397.1 KOS20560.1 - 2.2 7.5 13.2 0.5 9.6 1.7 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4618) APG6 PF04111.7 KOS20560.1 - 2.3 7.1 11.7 1.2 8.1 2.7 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 Macoilin PF09726.4 KOS20560.1 - 2.6 6.2 10.9 7 4.7 7.5 1.8 1 1 0 1 1 1 0 Transmembrane protein V_ATPase_I PF01496.14 KOS20560.1 - 3.2 5.4 5.9 7.8 4.2 0.3 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF1319 PF07028.6 KOS20560.1 - 3.9 7.6 8.9 5.3 7.2 0.6 3.6 2 1 2 4 4 3 0 Protein of unknown function (DUF1319) IFT57 PF10498.4 KOS20560.1 - 4.5 5.9 6.9 4.5 5.9 2.4 2.3 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 Mnd1 PF03962.10 KOS20560.1 - 4.7 6.8 14.2 2.6 7.6 1.5 3.5 2 1 1 3 3 3 0 Mnd1 family HALZ PF02183.13 KOS20560.1 - 5.1 6.8 8.1 34 4.2 0.0 4.3 4 1 2 6 6 6 0 Homeobox associated leucine zipper Prefoldin PF02996.12 KOS20560.1 - 7.6 6.2 10.3 18 4.9 0.3 4.2 4 1 1 5 5 4 0 Prefoldin subunit COG5 PF10392.4 KOS20560.1 - 8.4 6.3 8.1 2.6 8.0 1.1 2.9 2 1 1 3 3 3 0 Golgi transport complex subunit 5 DUF4201 PF13870.1 KOS20560.1 - 9.2 5.6 10.9 4.1 6.8 1.3 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.7 KOS20560.1 - 9.4 5.9 18.2 0.47 10.1 1.2 4.1 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein TPR_11 PF13414.1 KOS20561.1 - 7.6e-24 83.1 12.9 2.2e-10 40.0 0.2 5.2 4 1 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 KOS20561.1 - 1.8e-22 77.9 8.8 3.2e-07 29.6 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS20561.1 - 6.2e-22 75.7 13.5 9.6e-07 28.2 0.0 7.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KOS20561.1 - 1.2e-16 60.8 15.3 2.3e-05 24.9 0.0 5.8 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KOS20561.1 - 1.4e-15 56.3 17.7 3.5e-05 24.0 0.0 6.8 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 KOS20561.1 - 7.7e-15 53.7 4.8 0.048 13.8 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 KOS20561.1 - 4.8e-14 52.0 3.2 1.3e-07 31.4 0.0 5.2 4 1 2 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 KOS20561.1 - 1.2e-12 46.5 5.9 0.00011 21.7 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS20561.1 - 3.2e-12 46.6 14.5 0.0017 18.6 0.5 6.2 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 KOS20561.1 - 6.2e-12 44.3 4.0 0.004 16.8 0.0 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 KOS20561.1 - 1.6e-07 31.1 3.2 0.031 14.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KOS20561.1 - 1.7e-06 28.1 14.1 1.1 9.8 0.1 7.5 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 KOS20561.1 - 2.9e-05 23.2 4.8 0.068 12.2 0.0 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 KOS20561.1 - 0.00049 20.1 15.9 0.012 15.6 0.1 5.2 5 2 1 6 6 5 3 Tetratricopeptide repeat TPR_3 PF07720.7 KOS20561.1 - 0.016 14.9 0.1 16 5.4 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DED PF01335.16 KOS20561.1 - 0.049 13.7 0.1 8 6.6 0.0 2.5 2 0 0 2 2 2 0 Death effector domain BAF1_ABF1 PF04684.8 KOS20561.1 - 0.12 11.2 7.4 0.23 10.2 5.2 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TPR_10 PF13374.1 KOS20561.1 - 3 7.9 8.6 2 8.4 0.1 4.0 4 0 0 4 4 2 0 Tetratricopeptide repeat FHIPEP PF00771.15 KOS20561.1 - 3.5 5.8 5.2 5.2 5.2 3.6 1.1 1 0 0 1 1 1 0 FHIPEP family Med15 PF09606.5 KOS20561.1 - 8.3 4.4 49.3 13 3.8 34.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ferritin_2 PF13668.1 KOS20562.1 - 4.3e-17 62.3 0.0 6.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain HLH PF00010.21 KOS20563.1 - 2.4e-13 49.5 0.6 4.9e-13 48.5 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Rab5-bind PF09311.6 KOS20563.1 - 0.0028 17.5 0.9 0.0028 17.5 0.6 1.8 2 0 0 2 2 2 1 Rabaptin-like protein HALZ PF02183.13 KOS20563.1 - 0.01 15.5 0.2 0.025 14.2 0.1 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF1875 PF08961.5 KOS20563.1 - 0.017 14.4 1.5 0.018 14.3 0.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) TPR_MLP1_2 PF07926.7 KOS20563.1 - 0.076 12.7 3.7 0.16 11.7 2.2 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Herpes_BLRF2 PF05812.7 KOS20563.1 - 0.078 12.7 0.7 0.31 10.8 0.0 2.1 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein DUF904 PF06005.7 KOS20563.1 - 0.43 10.9 5.7 0.63 10.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Zn_clus PF00172.13 KOS20564.1 - 1.3e-08 34.6 16.4 2e-08 33.9 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dehydrin PF00257.14 KOS20564.1 - 0.11 12.7 4.6 0.37 11.1 0.4 2.2 2 0 0 2 2 2 0 Dehydrin Radical_SAM PF04055.16 KOS20565.1 - 3.2e-13 50.1 0.2 6.3e-13 49.2 0.2 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 KOS20565.1 - 3.9e-08 33.3 0.0 8.2e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 KOS20565.1 - 3.2e-07 30.5 0.0 6.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain ADK PF00406.17 KOS20566.1 - 1.4e-25 89.8 0.0 1.9e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 KOS20566.1 - 4.4e-11 42.8 0.0 6.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS20566.1 - 2e-08 35.1 0.0 2.9e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KOS20566.1 - 9.6e-07 29.1 0.0 1.3e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS20566.1 - 0.0038 16.3 0.0 0.008 15.2 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.24 KOS20566.1 - 0.06 13.5 0.0 0.23 11.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 KOS20566.1 - 0.075 12.4 0.1 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase ArgK PF03308.11 KOS20566.1 - 0.18 10.5 0.0 0.47 9.1 0.0 1.6 2 0 0 2 2 2 0 ArgK protein VWA PF00092.23 KOS20567.1 - 1.7e-08 34.3 0.0 2.8e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KOS20567.1 - 5.5e-08 33.1 0.3 1.9e-07 31.3 0.2 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KOS20567.1 - 0.00093 19.0 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.1 KOS20567.1 - 0.014 15.0 0.0 0.63 9.7 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Aminotran_1_2 PF00155.16 KOS20568.1 - 2.7e-36 125.2 0.0 3.7e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RRM_1 PF00076.17 KOS20569.1 - 1.9e-43 145.9 1.9 1.9e-20 72.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS20569.1 - 4.3e-35 119.5 0.4 2e-17 62.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KOS20569.1 - 4.1e-30 103.8 0.2 8.1e-30 102.9 0.1 1.5 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 KOS20569.1 - 3.7e-20 71.5 0.1 3.1e-08 33.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KOS20569.1 - 0.0026 17.5 0.9 0.11 12.2 0.0 3.2 3 1 0 3 3 3 1 RNA binding motif PRP38_assoc PF12871.2 KOS20569.1 - 0.02 15.3 37.9 0.02 15.3 26.2 3.4 3 1 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Nup35_RRM_2 PF14605.1 KOS20569.1 - 0.065 13.0 0.0 2.5 7.9 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif CDP-OH_P_transf PF01066.16 KOS20571.1 - 1.6e-17 63.6 8.3 4.4e-17 62.2 5.7 1.9 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase OMPdecase PF00215.19 KOS20572.1 - 3.4e-99 330.8 0.0 4.1e-99 330.5 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family FAP PF07174.6 KOS20574.1 - 4 6.6 12.7 4.6 6.4 8.8 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Ribonuclease_3 PF00636.21 KOS20575.1 - 1.2e-15 57.9 0.0 7e-15 55.4 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KOS20575.1 - 7e-10 38.9 0.0 2.4e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.20 KOS20575.1 - 0.0051 17.3 0.0 0.018 15.6 0.0 2.0 1 0 0 1 1 1 1 Double-stranded RNA binding motif PUF PF00806.14 KOS20576.1 - 2.6e-42 139.9 0.2 1.3e-06 27.5 0.0 8.9 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Epimerase PF01370.16 KOS20577.1 - 1e-12 48.0 0.1 1.7e-12 47.3 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KOS20577.1 - 3.5e-11 42.3 0.0 4.9e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KOS20577.1 - 7.8e-11 42.3 0.4 1.7e-10 41.2 0.3 1.6 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KOS20577.1 - 9.8e-06 24.6 1.2 0.00011 21.2 0.8 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KOS20577.1 - 2.6e-05 24.1 1.8 6.3e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KOS20577.1 - 0.0013 18.4 0.4 0.0032 17.1 0.1 1.8 2 0 0 2 2 2 1 KR domain NmrA PF05368.8 KOS20577.1 - 0.0092 15.2 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 KOS20577.1 - 0.029 13.2 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KOS20577.1 - 0.06 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Nfu_N PF08712.6 KOS20577.1 - 0.066 12.8 0.0 4.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Scaffold protein Nfu/NifU N terminal PP2C PF00481.16 KOS20578.1 - 5.9e-41 140.5 0.0 9.8e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KOS20578.1 - 0.0025 17.2 0.0 0.0062 15.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KOS20578.1 - 0.0031 17.2 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) DUF1751 PF08551.5 KOS20579.1 - 7.5e-06 26.1 0.2 1.3e-05 25.3 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KOS20579.1 - 5.8e-05 23.1 1.9 0.00016 21.6 1.3 1.7 1 1 0 1 1 1 1 Rhomboid family DER1 PF04511.10 KOS20579.1 - 0.0018 17.7 1.5 0.0026 17.2 1.0 1.1 1 0 0 1 1 1 1 Der1-like family Rick_17kDa_Anti PF05433.10 KOS20579.1 - 2.1 8.0 11.3 0.46 10.2 0.7 2.6 2 0 0 2 2 2 0 Glycine zipper 2TM domain Acid_PPase PF12689.2 KOS20580.1 - 3.9e-55 186.0 0.0 4.9e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase LRV PF01816.12 KOS20580.1 - 6.6 7.1 8.8 0.36 11.1 1.5 2.5 2 0 0 2 2 2 0 Leucine rich repeat variant CRAL_TRIO PF00650.15 KOS20581.1 - 5.2e-25 87.7 0.0 7.4e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KOS20581.1 - 4.8e-08 33.0 0.0 9.5e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Clp1 PF06807.9 KOS20582.1 - 5.5e-21 75.2 0.0 1e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_16 PF13191.1 KOS20582.1 - 2.5e-07 30.8 0.2 7e-07 29.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.12 KOS20582.1 - 2.5e-06 27.2 0.2 9.8e-06 25.2 0.1 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MobB PF03205.9 KOS20582.1 - 3.5e-06 26.7 0.0 7.6e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KOS20582.1 - 5.5e-06 26.0 0.1 1.2e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family CbiA PF01656.18 KOS20582.1 - 1.2e-05 24.8 0.1 2.2e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.1 KOS20582.1 - 1.9e-05 24.3 5.4 1.9e-05 24.3 3.7 3.0 2 1 1 3 3 3 1 Part of AAA domain AAA_17 PF13207.1 KOS20582.1 - 0.00026 21.7 0.1 0.0015 19.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KOS20582.1 - 0.00031 20.2 0.0 0.00055 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA PF00004.24 KOS20582.1 - 0.00031 20.9 0.0 0.001 19.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KOS20582.1 - 0.00039 19.9 0.0 0.00065 19.2 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain ArgK PF03308.11 KOS20582.1 - 0.0004 19.2 0.7 0.0004 19.2 0.5 1.6 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 KOS20582.1 - 0.0006 19.9 0.1 0.0015 18.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 KOS20582.1 - 0.0014 18.6 0.1 0.0032 17.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KOS20582.1 - 0.0016 17.6 0.0 0.0032 16.6 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_18 PF13238.1 KOS20582.1 - 0.0023 18.2 0.0 0.0042 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KOS20582.1 - 0.0024 17.2 0.2 0.0044 16.4 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SE PF00437.15 KOS20582.1 - 0.003 16.5 0.1 0.0048 15.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 KOS20582.1 - 0.0031 17.1 2.3 0.0031 17.1 1.6 1.8 2 0 0 2 2 1 1 AAA domain KTI12 PF08433.5 KOS20582.1 - 0.0032 16.7 0.0 0.0078 15.4 0.0 1.5 2 0 0 2 2 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KOS20582.1 - 0.0048 16.7 1.4 0.0079 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KOS20582.1 - 0.0053 16.4 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain SnoaL PF07366.7 KOS20582.1 - 0.0064 16.0 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase Zeta_toxin PF06414.7 KOS20582.1 - 0.0069 15.5 0.1 0.014 14.4 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KOS20582.1 - 0.0096 15.3 0.2 0.02 14.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KOS20582.1 - 0.01 14.8 0.0 0.029 13.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 KOS20582.1 - 0.016 15.1 0.4 0.26 11.2 0.0 2.9 3 1 0 3 3 2 0 50S ribosome-binding GTPase DAP3 PF10236.4 KOS20582.1 - 0.018 13.9 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.1 KOS20582.1 - 0.022 14.3 0.1 0.046 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.10 KOS20582.1 - 0.023 13.7 0.2 0.035 13.1 0.1 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase DUF2075 PF09848.4 KOS20582.1 - 0.025 13.5 0.1 0.039 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.7 KOS20582.1 - 0.028 13.4 0.1 0.056 12.4 0.1 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TrwB_AAD_bind PF10412.4 KOS20582.1 - 0.028 13.0 0.0 0.042 12.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 KOS20582.1 - 0.034 13.5 0.0 0.1 12.0 0.0 1.8 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 KOS20582.1 - 0.039 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 KOS20582.1 - 0.043 13.3 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_31 PF13614.1 KOS20582.1 - 0.048 13.5 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.15 KOS20582.1 - 0.048 12.1 0.0 0.068 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase ABC_tran PF00005.22 KOS20582.1 - 0.055 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 KOS20582.1 - 0.064 12.9 0.1 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 NTPase DUF853 PF05872.7 KOS20582.1 - 0.068 11.5 0.9 0.12 10.7 0.7 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Mg_chelatase PF01078.16 KOS20582.1 - 0.072 12.2 0.1 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.17 KOS20582.1 - 0.077 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 KOS20582.1 - 0.079 12.8 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain PIF1 PF05970.9 KOS20582.1 - 0.095 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Viral_helicase1 PF01443.13 KOS20582.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2791 PF10923.3 KOS20582.1 - 0.13 10.8 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_35 PF14516.1 KOS20582.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain IPK PF03770.11 KOS20583.1 - 6.4e-47 159.7 0.0 9.2e-47 159.2 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Synaptobrevin PF00957.16 KOS20584.1 - 2.1e-31 107.3 0.3 3.1e-31 106.8 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KOS20584.1 - 5.7e-23 80.2 0.0 9.7e-23 79.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain ODV-E18 PF10717.4 KOS20584.1 - 0.14 11.6 0.5 0.27 10.6 0.3 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 CcoS PF03597.10 KOS20584.1 - 2.4 7.6 6.7 4.6 6.7 4.7 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Ipi1_N PF12333.3 KOS20585.1 - 0.0016 18.3 2.5 2.7 8.0 0.0 4.9 6 0 0 6 6 6 2 Rix1 complex component involved in 60S ribosome maturation PI3_PI4_kinase PF00454.22 KOS20586.1 - 4e-39 134.4 0.1 2.1e-38 132.1 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KOS20586.1 - 4e-18 65.2 0.1 7e-18 64.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) HATPase_c_3 PF13589.1 KOS20588.1 - 1.8e-14 53.5 0.1 2.9e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 KOS20588.1 - 8.2e-12 44.6 0.0 1.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 KOS20588.1 - 1e-11 44.4 0.9 1.9e-11 43.6 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_12 PF13424.1 KOS20589.1 - 1.4e-13 50.5 4.9 5.3e-06 26.2 0.3 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KOS20589.1 - 1.1e-08 34.6 1.1 0.0077 15.8 0.4 4.3 2 2 2 4 4 4 3 TPR repeat TPR_14 PF13428.1 KOS20589.1 - 6.1e-08 32.6 14.3 0.52 11.0 0.4 5.7 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KOS20589.1 - 1.4e-07 31.9 20.0 0.01 16.5 2.0 4.5 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 KOS20589.1 - 1.2e-06 28.7 13.7 0.019 15.3 0.4 4.7 2 2 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS20589.1 - 3.8e-06 26.3 14.2 0.056 13.3 0.0 5.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.1 KOS20589.1 - 4.9e-05 23.1 13.0 0.092 12.7 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KOS20589.1 - 0.0002 20.8 1.2 7.9 6.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KOS20589.1 - 0.00035 20.5 1.4 45 4.5 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 KOS20589.1 - 0.00049 19.6 3.5 13 5.8 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KOS20589.1 - 0.11 12.9 6.8 58 4.4 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 KOS20589.1 - 0.31 11.1 5.1 3.7 7.7 0.3 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KOS20589.1 - 9.5 6.1 13.7 0.26 11.1 0.8 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat RWD PF05773.17 KOS20590.1 - 3.1e-19 68.9 0.0 7.5e-19 67.7 0.0 1.6 1 1 0 1 1 1 1 RWD domain Muted PF14942.1 KOS20590.1 - 0.041 13.7 3.4 1.3 8.9 0.3 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein KfrA_N PF11740.3 KOS20590.1 - 0.22 11.9 10.8 0.36 11.2 3.6 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term zf-C3HC4_2 PF13923.1 KOS20592.1 - 4.8e-08 32.8 7.2 8.5e-08 32.0 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS20592.1 - 1.2e-07 31.2 6.2 2.1e-07 30.4 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS20592.1 - 1.5e-07 31.1 5.5 2.5e-07 30.3 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KOS20592.1 - 5.2e-07 29.2 4.8 9.1e-07 28.4 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS20592.1 - 1.7e-06 27.6 4.6 2.9e-06 26.9 3.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KOS20592.1 - 9.7e-06 25.3 5.5 6.2e-05 22.7 3.7 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KOS20592.1 - 0.00039 20.0 3.8 0.00041 19.9 1.6 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 KOS20592.1 - 0.084 12.4 2.8 0.14 11.6 2.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 KOS20592.1 - 0.28 11.3 2.8 0.72 10.0 2.0 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger FYVE PF01363.16 KOS20592.1 - 0.36 10.7 2.9 0.91 9.4 2.0 1.6 1 1 0 1 1 1 0 FYVE zinc finger zf-MIZ PF02891.15 KOS20592.1 - 1.1 8.7 7.4 3.2 7.3 5.2 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Histone_HNS PF00816.16 KOS20592.1 - 6.4 7.3 7.9 0.86 10.1 0.5 2.8 2 1 0 2 2 2 0 H-NS histone family Mpp10 PF04006.7 KOS20593.1 - 6.7e-101 338.5 56.4 8e-98 328.3 39.1 2.2 1 1 0 1 1 1 1 Mpp10 protein TFIIA PF03153.8 KOS20593.1 - 0.0052 16.7 14.6 0.0052 16.7 10.1 3.0 4 0 0 4 4 4 1 Transcription factor IIA, alpha/beta subunit DUF4645 PF15488.1 KOS20593.1 - 2.1 7.4 4.5 0.25 10.4 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4645) Hid1 PF12722.2 KOS20593.1 - 6.6 4.2 5.1 11 3.5 3.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SHNi-TPR PF10516.4 KOS20594.1 - 4.3e-12 45.0 0.1 4.3e-12 45.0 0.1 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.1 KOS20594.1 - 7.3e-08 32.2 7.1 0.00033 20.5 0.1 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KOS20594.1 - 4.8e-07 29.3 4.3 0.00047 19.7 0.0 3.5 3 1 1 4 4 4 3 TPR repeat TPR_16 PF13432.1 KOS20594.1 - 4.6e-05 23.9 4.0 0.0002 21.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KOS20594.1 - 0.00058 19.5 6.5 0.46 10.5 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Abhydrolase_5 PF12695.2 KOS20594.1 - 0.024 14.3 0.2 0.066 12.9 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family TBCA PF02970.11 KOS20594.1 - 0.085 12.9 0.1 0.085 12.9 0.1 3.6 2 2 1 3 3 3 0 Tubulin binding cofactor A V-SNARE PF05008.10 KOS20594.1 - 0.3 11.2 6.1 0.51 10.5 0.0 3.3 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DHquinase_I PF01487.10 KOS20595.1 - 5.8e-35 120.9 0.0 6.9e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Type I 3-dehydroquinase MFS_1 PF07690.11 KOS20597.1 - 2.1e-07 29.9 18.1 2.1e-07 29.9 12.6 4.8 3 2 1 4 4 4 3 Major Facilitator Superfamily Fungal_trans PF04082.13 KOS20598.1 - 2.9e-33 114.8 0.0 7.7e-21 74.1 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS20598.1 - 3.6e-10 39.5 9.7 7.9e-10 38.4 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.1 KOS20599.1 - 1.9e-28 99.3 0.0 2.7e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KOS20599.1 - 0.00014 22.0 0.1 0.00028 21.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PBP1_TM PF14812.1 KOS20599.1 - 8.2 6.8 9.3 0.26 11.6 2.2 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 KOS20600.1 - 0.021 14.0 0.1 0.03 13.4 0.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Paf1 PF03985.8 KOS20600.1 - 0.14 10.8 5.1 0.2 10.3 3.6 1.1 1 0 0 1 1 1 0 Paf1 Fungal_trans_2 PF11951.3 KOS20600.1 - 0.14 10.6 0.0 0.14 10.6 0.0 1.8 3 0 0 3 3 3 0 Fungal specific transcription factor domain Daxx PF03344.10 KOS20600.1 - 0.67 8.3 8.4 0.93 7.9 5.8 1.1 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 KOS20600.1 - 1.1 9.5 8.3 2.2 8.6 5.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FLO_LFY PF01698.11 KOS20600.1 - 1.3 7.7 6.0 2.1 7.0 4.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Metallophos PF00149.23 KOS20601.1 - 1.6e-10 40.7 1.9 3.6e-10 39.5 1.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SPT6_acidic PF14632.1 KOS20601.1 - 8 6.6 16.2 13 6.0 4.0 2.9 2 0 0 2 2 2 0 Acidic N-terminal SPT6 V-ATPase_H_N PF03224.9 KOS20603.1 - 5.7e-69 232.6 0.0 8.2e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KOS20603.1 - 4.3e-39 133.1 0.6 1.6e-38 131.2 0.1 2.2 3 0 0 3 3 3 1 V-ATPase subunit H HEAT_2 PF13646.1 KOS20603.1 - 0.0011 19.1 0.8 0.044 14.0 0.0 3.0 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 KOS20603.1 - 0.087 13.3 0.9 2.2 8.8 0.0 3.5 2 2 1 3 3 3 0 HEAT-like repeat Arm PF00514.18 KOS20603.1 - 0.1 12.4 0.1 43 4.1 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat OmdA PF13376.1 KOS20603.1 - 0.14 11.8 0.9 1.6 8.4 0.3 2.3 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated GCV_T PF01571.16 KOS20604.1 - 2.4e-56 190.4 0.1 3.9e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KOS20604.1 - 7.3e-23 80.4 2.8 1.5e-22 79.4 1.9 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Vps26 PF03643.10 KOS20605.1 - 1e-124 414.7 1.4 2.3e-103 344.7 0.4 2.0 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KOS20605.1 - 0.00021 21.1 0.0 1.4 8.7 0.0 3.4 2 1 1 3 3 3 3 Arrestin (or S-antigen), N-terminal domain Ribosomal_L6 PF00347.18 KOS20606.1 - 6.9e-24 84.1 6.9 2.1e-13 50.5 2.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Nup160 PF11715.3 KOS20607.1 - 9.5e-124 413.4 4.4 1.3e-123 413.0 3.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_8 PF13181.1 KOS20607.1 - 0.044 13.5 0.1 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2622 PF11080.3 KOS20607.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2622) RRM_1 PF00076.17 KOS20608.1 - 1.3e-17 63.1 0.0 1.9e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS20608.1 - 2.8e-14 52.8 0.0 5.5e-14 51.8 0.0 1.5 1 1 1 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS20608.1 - 9.3e-10 38.2 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KOS20608.1 - 0.023 14.4 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KOS20608.1 - 0.037 13.7 0.1 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 WD40 PF00400.27 KOS20609.1 - 5.2e-18 64.1 1.2 7.2e-06 25.6 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat SRA1 PF07304.6 KOS20609.1 - 9e-11 41.7 0.0 3e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 KOS20609.1 - 2.9e-08 33.8 0.1 8.3e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 HLH PF00010.21 KOS20610.1 - 1.3e-07 31.1 0.5 2.8e-07 30.1 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TIP49 PF06068.8 KOS20611.1 - 2.2e-173 576.5 1.8 2.7e-173 576.2 1.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KOS20611.1 - 1.6e-09 37.2 0.4 1.3e-05 24.3 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KOS20611.1 - 2.1e-08 34.4 0.7 3.8e-05 23.8 0.0 3.4 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 KOS20611.1 - 1.1e-05 24.4 0.5 1.8e-05 23.7 0.4 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 KOS20611.1 - 0.0002 21.4 0.0 0.0016 18.4 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KOS20611.1 - 0.00034 20.7 0.0 0.41 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KOS20611.1 - 0.00091 19.1 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KOS20611.1 - 0.004 16.3 0.5 0.11 11.6 0.2 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KOS20611.1 - 0.017 14.5 0.1 0.041 13.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KOS20611.1 - 0.018 14.7 0.3 7 6.3 0.0 3.4 3 1 1 4 4 4 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KOS20611.1 - 0.025 14.2 0.8 0.098 12.4 0.4 2.1 1 1 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 KOS20611.1 - 0.027 13.9 0.1 8.6 5.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_32 PF13654.1 KOS20611.1 - 0.064 11.9 0.1 0.2 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KOS20611.1 - 0.11 12.4 0.1 0.64 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 KOS20611.1 - 0.15 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 GET2 PF08690.5 KOS20612.1 - 1.8e-08 33.9 5.4 9e-07 28.4 3.7 2.9 1 1 0 1 1 1 1 GET complex subunit GET2 Cytochrom_B_N PF00033.14 KOS20612.1 - 0.051 12.9 1.0 0.1 11.9 0.7 1.5 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Menin PF05053.8 KOS20612.1 - 0.29 9.2 4.3 0.38 8.8 2.9 1.1 1 0 0 1 1 1 0 Menin AMP-binding PF00501.23 KOS20614.1 - 1.6e-80 270.5 0.2 3.4e-80 269.4 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme SPC12 PF06645.8 KOS20614.1 - 0.27 11.0 2.5 0.83 9.5 0.0 2.5 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2781 PF10914.3 KOS20615.1 - 4.1e-14 52.6 13.8 4.8e-14 52.3 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Pyridoxal_deC PF00282.14 KOS20616.1 - 1.5e-15 56.5 0.0 9.1e-15 53.9 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KOS20616.1 - 0.024 13.8 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase RGS PF00615.14 KOS20617.1 - 0.00016 21.7 0.0 0.00031 20.8 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain CN_hydrolase PF00795.17 KOS20618.1 - 3.8e-20 72.0 0.0 7.1e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KOS20618.1 - 1.6e-16 59.9 0.0 1.3e-15 57.0 0.0 2.2 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 KOS20618.1 - 0.06 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase MFS_1 PF07690.11 KOS20619.1 - 5.4e-09 35.2 3.9 6.9e-09 34.8 2.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS20619.1 - 0.003 16.2 2.3 0.0034 16.0 1.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2301 PF10063.4 KOS20619.1 - 0.094 12.9 0.8 0.16 12.1 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) MIP PF00230.15 KOS20620.1 - 5.2e-21 75.1 13.8 3.9e-20 72.2 9.5 1.9 1 1 0 1 1 1 1 Major intrinsic protein ATG22 PF11700.3 KOS20621.1 - 4.5e-88 295.8 19.1 1.6e-50 172.0 7.2 2.0 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like His_Phos_2 PF00328.17 KOS20622.1 - 2.6e-34 119.1 0.0 3.2e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_S8 PF00082.17 KOS20623.1 - 2.3e-41 141.8 7.1 3e-41 141.4 4.9 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KOS20623.1 - 1.5e-16 60.7 0.0 2.3e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 ETC_C1_NDUFA4 PF04800.7 KOS20625.1 - 8.8e-37 125.0 0.9 8.8e-37 125.0 0.6 1.6 2 0 0 2 2 2 1 ETC complex I subunit conserved region CLTH PF10607.4 KOS20626.1 - 2.9e-32 111.3 0.4 4.3e-32 110.8 0.1 1.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KOS20626.1 - 8.2e-10 38.1 0.0 2e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 LisH F1F0-ATPsyn_F PF10791.4 KOS20628.1 - 1.3e-41 140.7 0.4 1.5e-41 140.5 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi RNase_T PF00929.19 KOS20629.1 - 3.2e-25 89.3 0.0 5.5e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KOS20629.1 - 0.00013 21.4 0.0 0.00026 20.5 0.0 1.4 1 1 0 1 1 1 1 3'-5' exonuclease Ndc1_Nup PF09531.5 KOS20629.1 - 8.4 4.6 5.6 13 4.0 3.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MCM PF00493.18 KOS20630.1 - 1.8e-136 454.3 0.8 3.3e-136 453.4 0.6 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KOS20630.1 - 6e-21 75.1 0.0 2.2e-20 73.3 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KOS20630.1 - 3.7e-07 29.5 0.0 1e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KOS20630.1 - 0.0012 18.2 0.0 0.0029 17.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KOS20630.1 - 0.0016 18.0 0.2 0.005 16.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS20630.1 - 0.024 14.3 0.0 0.22 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF1237 PF06824.6 KOS20631.1 - 2.3e-178 593.1 0.0 2.6e-178 592.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) MOZ_SAS PF01853.13 KOS20632.1 - 3.5e-86 287.2 0.4 5e-86 286.7 0.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KOS20632.1 - 1.1e-17 63.4 0.0 5.7e-17 61.1 0.0 2.2 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.1 KOS20632.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS20632.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Glyco_transf_90 PF05686.7 KOS20633.1 - 3.3e-13 49.1 1.4 1.9e-12 46.5 1.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 KOS20633.1 - 0.011 15.9 0.0 0.022 15.0 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferases group 1 PRK PF00485.13 KOS20634.1 - 5.7e-41 140.2 0.0 5.8e-40 136.9 0.0 2.2 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 KOS20634.1 - 1e-38 132.6 0.0 1.5e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 KOS20634.1 - 8.2e-08 33.0 0.0 3.2e-07 31.2 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KOS20634.1 - 3.3e-06 27.4 0.0 1.1e-05 25.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS20634.1 - 0.00046 20.0 0.1 0.004 17.0 0.0 2.3 3 0 0 3 3 2 1 AAA domain CPT PF07931.7 KOS20634.1 - 0.001 18.7 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.1 KOS20634.1 - 0.0016 17.9 0.1 0.0082 15.6 0.1 2.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KOS20634.1 - 0.0016 18.4 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KOS20634.1 - 0.0021 18.2 0.0 0.0086 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KOS20634.1 - 0.0027 17.7 1.1 0.016 15.2 0.1 2.4 2 1 1 3 3 3 1 AAA ATPase domain Pribosyltran PF00156.22 KOS20634.1 - 0.0037 16.9 0.1 0.27 10.9 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosyl transferase domain ABC_tran PF00005.22 KOS20634.1 - 0.0058 16.9 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 KOS20634.1 - 0.0063 15.4 0.0 0.015 14.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Cytidylate_kin2 PF13189.1 KOS20634.1 - 0.0087 15.9 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase-like family RNA_helicase PF00910.17 KOS20634.1 - 0.0091 16.1 0.1 0.025 14.7 0.0 1.8 2 0 0 2 2 1 1 RNA helicase MobB PF03205.9 KOS20634.1 - 0.013 15.2 0.1 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KOS20634.1 - 0.018 13.9 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KOS20634.1 - 0.026 14.0 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family SKI PF01202.17 KOS20634.1 - 0.032 14.1 0.0 0.24 11.2 0.0 2.4 3 0 0 3 3 2 0 Shikimate kinase DUF258 PF03193.11 KOS20634.1 - 0.045 12.9 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 KOS20634.1 - 0.047 13.3 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF87 PF01935.12 KOS20634.1 - 0.06 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 KOS20634.1 - 0.06 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 KOS20634.1 - 0.12 11.7 0.3 0.27 10.6 0.2 1.5 1 0 0 1 1 1 0 AAA-like domain APS_kinase PF01583.15 KOS20634.1 - 0.14 11.8 0.1 0.38 10.4 0.0 1.8 2 0 0 2 2 1 0 Adenylylsulphate kinase CbiA PF01656.18 KOS20634.1 - 0.28 10.5 1.2 1.7 8.0 0.2 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RRM_1 PF00076.17 KOS20635.1 - 2e-13 49.7 0.6 3e-13 49.1 0.2 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS20635.1 - 3.8e-09 36.2 0.0 5.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS20635.1 - 5.9e-08 32.5 0.1 1.1e-07 31.7 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KOS20635.1 - 0.036 13.6 0.1 0.041 13.4 0.1 1.1 1 0 0 1 1 1 0 Calcipressin Guanylate_cyc PF00211.15 KOS20635.1 - 0.067 12.5 0.0 0.075 12.3 0.0 1.1 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain RRM_3 PF08777.6 KOS20635.1 - 0.071 12.9 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Limkain-b1 PF11608.3 KOS20635.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 ATP-synt_D PF01813.12 KOS20636.1 - 7.3e-37 126.8 0.1 9.4e-37 126.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit D TPR_12 PF13424.1 KOS20637.1 - 1.9e-06 27.7 0.7 0.86 9.5 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat Suf PF05843.9 KOS20637.1 - 5.7e-05 22.9 4.0 0.03 14.0 1.0 3.2 2 2 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_15 PF13429.1 KOS20637.1 - 0.0037 16.3 0.3 0.0093 15.0 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 KOS20637.1 - 0.018 14.8 0.1 0.36 10.6 0.1 2.7 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 TPR_14 PF13428.1 KOS20637.1 - 0.055 14.1 12.7 25 5.8 0.2 6.8 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 KOS20637.1 - 8.1 6.6 8.7 26 5.0 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat PolyA_pol PF01743.15 KOS20638.1 - 3.7e-24 85.3 1.1 1e-23 83.9 0.1 2.3 2 1 0 2 2 2 1 Poly A polymerase head domain DUF3666 PF12408.3 KOS20638.1 - 0.041 12.9 0.0 0.12 11.5 0.0 1.8 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase PolyA_pol_RNAbd PF12627.2 KOS20638.1 - 0.083 12.4 0.0 0.23 11.0 0.0 1.8 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A Anp1 PF03452.9 KOS20639.1 - 1e-121 405.1 0.3 3.4e-121 403.5 0.0 1.7 2 0 0 2 2 2 1 Anp1 Rad54_N PF08658.5 KOS20639.1 - 0.063 13.0 1.8 0.11 12.2 1.2 1.3 1 0 0 1 1 1 0 Rad54 N terminal Sec7 PF01369.15 KOS20640.1 - 9.1e-59 198.3 0.0 2.2e-58 197.0 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KOS20640.1 - 9.3e-19 67.4 0.1 1.8e-11 43.7 0.1 2.6 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Syja_N PF02383.13 KOS20641.1 - 5e-62 209.5 0.1 2.1e-31 108.9 0.0 2.5 2 1 0 3 3 3 2 SacI homology domain DUF2454 PF10521.4 KOS20642.1 - 1.5e-46 158.6 0.0 2.1e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) V_ATPase_I PF01496.14 KOS20643.1 - 8.1e-284 943.2 0.1 9.4e-284 943.0 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ERM PF00769.14 KOS20643.1 - 0.0017 17.9 6.8 0.017 14.6 0.2 2.2 2 0 0 2 2 2 1 Ezrin/radixin/moesin family AAA_13 PF13166.1 KOS20643.1 - 0.0055 15.2 2.5 0.92 7.8 0.7 2.1 2 0 0 2 2 2 2 AAA domain DUF3552 PF12072.3 KOS20643.1 - 0.013 14.7 3.0 0.9 8.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Serine_rich PF08824.5 KOS20643.1 - 0.03 14.0 2.9 0.066 12.9 0.1 2.2 2 0 0 2 2 2 0 Serine rich protein interaction domain IncA PF04156.9 KOS20643.1 - 0.033 13.7 0.5 0.033 13.7 0.3 3.0 3 0 0 3 3 3 0 IncA protein AAA_27 PF13514.1 KOS20643.1 - 0.038 11.7 8.7 0.025 12.2 1.3 2.0 2 0 0 2 2 2 0 AAA domain PV-1 PF06637.6 KOS20643.1 - 0.071 11.6 2.2 0.14 10.6 1.5 1.4 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF4140 PF13600.1 KOS20643.1 - 0.14 12.6 6.6 2.3 8.6 0.9 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF342 PF03961.8 KOS20643.1 - 0.18 10.1 3.3 0.96 7.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Baculo_PEP_C PF04513.7 KOS20643.1 - 0.24 11.1 8.0 2.5 7.9 2.7 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 KOS20643.1 - 0.41 10.4 4.3 3.3 7.5 0.4 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.15 KOS20643.1 - 0.49 10.1 10.0 2.6 7.8 0.2 3.0 3 0 0 3 3 3 0 Prefoldin subunit TBPIP PF07106.8 KOS20643.1 - 0.54 9.7 8.1 2.4 7.6 0.1 2.5 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) OmpH PF03938.9 KOS20643.1 - 0.88 9.4 8.9 0.33 10.8 0.9 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Siah-Interact_N PF09032.6 KOS20643.1 - 1.2 9.2 7.7 0.11 12.6 1.7 1.9 2 0 0 2 2 2 0 Siah interacting protein, N terminal PspB PF06667.7 KOS20643.1 - 2 8.4 5.8 0.7 9.8 0.1 2.9 3 0 0 3 3 3 0 Phage shock protein B GvpK PF05121.7 KOS20643.1 - 3.8 7.4 10.0 3.8 7.3 0.6 3.3 2 1 1 3 3 3 0 Gas vesicle protein K Filament PF00038.16 KOS20643.1 - 4.2 6.7 14.9 1.3 8.4 2.0 2.7 2 1 0 2 2 2 0 Intermediate filament protein MerR-DNA-bind PF09278.6 KOS20643.1 - 9.7 6.6 8.2 2.1 8.8 0.8 3.0 3 0 0 3 3 3 0 MerR, DNA binding CPSF73-100_C PF11718.3 KOS20644.1 - 5.9e-73 244.7 0.0 3.2e-71 239.1 0.0 2.2 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KOS20644.1 - 7.8e-32 109.8 0.0 2e-31 108.5 0.0 1.7 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 KOS20644.1 - 4.2e-14 52.6 0.7 7.8e-14 51.7 0.5 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KOS20644.1 - 1.7e-12 47.3 0.7 3e-12 46.5 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KOS20644.1 - 2.1e-07 30.6 0.3 4.2e-07 29.6 0.2 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 KOS20644.1 - 1.4e-05 24.8 1.8 1.8e-05 24.4 0.2 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain TAF4 PF05236.9 KOS20645.1 - 1.1e-09 38.0 12.9 9.6e-09 34.8 7.7 3.0 2 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family WD40 PF00400.27 KOS20646.1 - 2.3e-77 252.3 15.8 4.1e-11 42.3 0.7 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KOS20646.1 - 5.5e-08 31.4 1.1 0.0097 14.0 0.1 4.0 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KOS20646.1 - 0.023 13.4 0.0 2.2 6.9 0.0 3.1 1 1 1 3 3 3 0 Nup133 N terminal like Prenyltransf PF01255.14 KOS20647.1 - 2e-89 298.5 0.0 2.7e-89 298.1 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Ycf1 PF05758.7 KOS20647.1 - 0.016 12.9 1.8 0.019 12.7 1.3 1.1 1 0 0 1 1 1 0 Ycf1 DUF4628 PF15429.1 KOS20647.1 - 0.053 12.9 6.7 0.082 12.3 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Daxx PF03344.10 KOS20647.1 - 0.058 11.8 10.2 0.082 11.3 7.1 1.2 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 KOS20647.1 - 0.14 12.2 7.4 0.21 11.6 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) AAA_assoc_C PF09821.4 KOS20647.1 - 0.32 11.2 3.1 0.52 10.5 1.6 1.7 2 0 0 2 2 2 0 C-terminal AAA-associated domain Pox_Ag35 PF03286.9 KOS20647.1 - 0.49 9.8 7.2 0.78 9.2 5.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein YqfQ PF14181.1 KOS20647.1 - 0.59 10.1 7.9 1 9.4 5.5 1.3 1 0 0 1 1 1 0 YqfQ-like protein Hid1 PF12722.2 KOS20647.1 - 0.88 7.1 5.5 1.1 6.8 3.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CobT PF06213.7 KOS20647.1 - 1.4 7.9 14.3 2.3 7.3 9.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4637 PF15470.1 KOS20647.1 - 3.9 7.0 9.4 6.6 6.3 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Paf1 PF03985.8 KOS20647.1 - 4.8 5.8 14.2 7 5.2 9.9 1.1 1 0 0 1 1 1 0 Paf1 BAF1_ABF1 PF04684.8 KOS20647.1 - 5.9 5.6 8.7 8.5 5.1 6.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PHD PF00628.24 KOS20648.1 - 2.4e-09 36.7 8.3 4e-09 36.0 5.8 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KOS20648.1 - 8.7e-06 25.9 4.7 0.024 14.9 0.0 3.1 3 0 0 3 3 3 2 Inhibitor of growth proteins N-terminal histone-binding Ribosomal_L24e PF01246.15 KOS20649.1 - 1.8e-29 101.3 2.5 3.6e-29 100.4 1.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e Atg14 PF10186.4 KOS20649.1 - 3.9 6.3 5.9 4.9 6.0 4.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LRR_4 PF12799.2 KOS20650.1 - 0.0066 16.0 4.5 4.5 7.0 0.6 4.6 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) OSCP PF00213.13 KOS20651.1 - 6.6e-46 156.3 0.9 9.1e-46 155.8 0.6 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Glyco_hydro_63 PF03200.11 KOS20652.1 - 5.2e-09 34.5 6.6 1.5e-06 26.4 0.2 3.6 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase PBP1_TM PF14812.1 KOS20654.1 - 0.92 9.8 4.0 1.1 9.6 2.8 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_60s PF00428.14 KOS20654.1 - 0.94 9.9 13.9 0.51 10.7 8.4 1.5 1 1 0 1 1 1 0 60s Acidic ribosomal protein TRAP_alpha PF03896.11 KOS20654.1 - 1.9 7.3 5.0 2 7.3 3.5 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Aminotran_1_2 PF00155.16 KOS20655.1 - 4.4e-19 68.6 0.0 6.7e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Snf7 PF03357.16 KOS20656.1 - 1e-20 73.7 15.8 1.6e-20 73.1 11.0 1.3 1 0 0 1 1 1 1 Snf7 DUF2098 PF09871.4 KOS20656.1 - 1.2 9.1 6.8 3.7 7.5 2.8 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Phage_Gp23 PF10669.4 KOS20656.1 - 1.7 8.7 0.0 1.7 8.7 0.0 2.8 2 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF2422 PF10337.4 KOS20656.1 - 6.8 5.3 6.7 11 4.6 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) RRN3 PF05327.6 KOS20656.1 - 8.5 4.3 9.4 1.7 6.6 4.3 1.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 TRAPPC-Trs85 PF12739.2 KOS20657.1 - 3e-115 385.2 1.6 4.2e-115 384.7 1.1 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Bud13 PF09736.4 KOS20658.1 - 2.5e-47 160.8 9.6 2.5e-47 160.8 6.6 2.1 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex TFIIF_alpha PF05793.7 KOS20659.1 - 0.6 8.4 52.7 3.9 5.7 36.3 2.8 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAP_assoc PF03828.14 KOS20660.1 - 8.9e-18 64.0 0.0 7.6e-12 45.0 0.0 2.4 2 0 0 2 2 2 2 Cid1 family poly A polymerase PAP_central PF04928.12 KOS20660.1 - 0.044 12.6 0.0 3.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Poly(A) polymerase central domain XPG_I_2 PF12813.2 KOS20661.1 - 1.3e-34 119.8 0.0 2e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 KOS20661.1 - 0.0088 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 XPG I-region Pribosyl_synth PF14572.1 KOS20662.1 - 2.8e-37 128.2 0.2 1.1e-30 106.7 0.0 2.6 2 1 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KOS20662.1 - 2.1e-35 120.9 0.1 2e-33 114.5 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KOS20662.1 - 5e-05 23.0 0.1 0.0029 17.3 0.0 2.7 3 0 0 3 3 3 1 Phosphoribosyl transferase domain Nop53 PF07767.6 KOS20663.1 - 1.8e-98 330.0 18.9 2.2e-98 329.7 13.1 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Drc1-Sld2 PF11719.3 KOS20663.1 - 0.045 12.8 12.1 0.059 12.4 8.4 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Pyr_redox_2 PF07992.9 KOS20664.1 - 1e-24 87.5 0.0 1.3e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS20664.1 - 6.4e-16 58.5 0.0 3.1e-11 43.5 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 KOS20664.1 - 7.4e-07 28.0 0.3 1.6e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KOS20664.1 - 6.9e-06 26.1 0.1 2.4e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KOS20664.1 - 2.2e-05 23.9 0.5 7.9e-05 22.2 0.4 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KOS20664.1 - 8.1e-05 21.7 1.5 0.00018 20.6 1.1 1.6 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.1 KOS20664.1 - 0.00042 20.4 0.0 0.68 9.9 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.1 KOS20664.1 - 0.078 12.6 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Rib_5-P_isom_A PF06026.9 KOS20665.1 - 2.6e-40 137.5 0.0 6.4e-36 123.2 0.0 2.1 2 0 0 2 2 2 2 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 KOS20665.1 - 0.0065 16.1 0.0 3.7 7.1 0.0 3.1 3 0 0 3 3 3 2 DeoR C terminal sensor domain Ras PF00071.17 KOS20666.1 - 1.3e-59 200.1 0.4 1.8e-59 199.7 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS20666.1 - 1.5e-21 77.0 0.1 2.4e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS20666.1 - 7e-18 64.4 0.2 8.9e-18 64.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KOS20666.1 - 1.3e-08 34.5 0.0 5.9e-08 32.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KOS20666.1 - 1.6e-06 27.4 0.2 2.1e-06 27.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KOS20666.1 - 8e-06 25.7 0.0 1.3e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KOS20666.1 - 1.5e-05 24.3 0.0 2.3e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 KOS20666.1 - 0.028 14.2 0.2 3 7.6 0.0 2.5 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 KOS20666.1 - 0.063 13.1 0.2 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KOS20666.1 - 0.072 12.8 0.3 4 7.1 0.0 2.7 2 1 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KOS20666.1 - 0.13 12.4 0.1 1.7 8.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain TPR_12 PF13424.1 KOS20667.1 - 2.3e-10 40.2 20.9 0.0011 18.7 0.3 8.5 11 1 0 11 11 11 4 Tetratricopeptide repeat AAA_16 PF13191.1 KOS20667.1 - 1.4e-08 34.9 0.0 8e-08 32.4 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain TPR_7 PF13176.1 KOS20667.1 - 2.5e-07 29.9 6.0 0.44 10.4 0.0 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KOS20667.1 - 9e-06 25.9 3.5 0.77 10.1 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat AAA_22 PF13401.1 KOS20667.1 - 0.00023 21.3 0.0 0.0022 18.1 0.0 2.8 1 0 0 1 1 1 1 AAA domain TPR_14 PF13428.1 KOS20667.1 - 0.005 17.3 6.6 14 6.6 0.1 7.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_10 PF13374.1 KOS20667.1 - 0.013 15.4 3.5 36 4.4 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA_17 PF13207.1 KOS20667.1 - 0.023 15.5 0.0 0.34 11.7 0.0 3.0 2 1 1 3 3 3 0 AAA domain NACHT PF05729.7 KOS20667.1 - 0.029 14.0 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 NACHT domain p450 PF00067.17 KOS20668.1 - 3e-42 144.7 0.0 4e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cys_Met_Meta_PP PF01053.15 KOS20669.1 - 4.9e-23 81.0 0.0 7.7e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KOS20669.1 - 0.00037 19.5 0.0 0.00065 18.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KOS20669.1 - 0.0071 15.5 0.0 0.017 14.2 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase RPE65 PF03055.10 KOS20670.1 - 1.3e-104 350.4 0.0 1.8e-104 350.0 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein FMN_bind_2 PF04299.7 KOS20671.1 - 5.6e-51 172.3 0.0 7.4e-51 171.9 0.0 1.2 1 0 0 1 1 1 1 Putative FMN-binding domain FMO-like PF00743.14 KOS20672.1 - 4.5e-26 91.1 0.0 8.2e-18 63.8 0.0 3.2 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KOS20672.1 - 6.4e-10 39.4 0.0 1.8e-07 31.4 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KOS20672.1 - 7e-08 31.7 0.0 5.8e-06 25.4 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KOS20672.1 - 4.9e-06 26.3 0.0 0.068 12.9 0.0 3.0 2 1 1 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KOS20672.1 - 1.1e-05 25.4 0.0 0.00033 20.5 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KOS20672.1 - 0.0094 16.0 0.1 0.3 11.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KOS20672.1 - 0.021 14.8 0.0 0.058 13.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KOS20672.1 - 0.098 11.5 0.2 9.6 4.9 0.0 3.2 3 1 0 3 3 3 0 FAD dependent oxidoreductase NUDIX PF00293.23 KOS20673.1 - 1.8e-07 30.8 0.0 3.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Glyco_hydro_16 PF00722.16 KOS20674.1 - 7.4e-12 44.9 3.5 1.1e-11 44.3 2.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Methyltransf_18 PF12847.2 KOS20674.1 - 1.9e-08 34.8 0.0 4.3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS20674.1 - 9.2e-08 32.4 0.0 2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS20674.1 - 3.9e-06 26.5 0.0 6.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS20674.1 - 8.8e-06 25.7 0.1 2.2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS20674.1 - 1.7e-05 25.0 0.0 5e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS20674.1 - 0.00053 20.4 0.0 0.001 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF374 PF04028.8 KOS20674.1 - 0.069 12.4 0.0 0.26 10.5 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF374) NMO PF03060.10 KOS20675.1 - 7.1e-34 117.4 7.6 8.9e-27 94.0 2.1 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KOS20675.1 - 1.3e-05 24.3 1.0 0.024 13.5 1.2 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KOS20675.1 - 0.00011 21.1 6.4 0.00013 20.9 2.8 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KOS20675.1 - 0.021 13.7 2.3 0.042 12.7 1.6 1.4 1 1 0 1 1 1 0 Conserved region in glutamate synthase Cyclin_N PF00134.18 KOS20676.1 - 3e-05 23.5 0.0 5.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain BAR PF03114.13 KOS20677.1 - 5.1e-42 143.9 10.1 5.8e-42 143.7 7.0 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 KOS20677.1 - 7.5e-08 31.6 3.4 8.4e-08 31.4 2.3 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Lectin_N PF03954.9 KOS20677.1 - 0.19 11.1 0.8 0.45 9.9 0.2 1.8 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain APG6 PF04111.7 KOS20677.1 - 1.7 7.6 9.4 0.62 9.0 4.4 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF733 PF05306.6 KOS20677.1 - 5.8 7.2 9.5 1.3 9.3 1.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF733) Pro_CA PF00484.14 KOS20678.1 - 8.2e-21 74.6 0.0 1.3e-20 73.9 0.0 1.3 1 1 0 1 1 1 1 Carbonic anhydrase Thioredoxin PF00085.15 KOS20679.1 - 8.7e-27 92.8 0.0 9.4e-27 92.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KOS20679.1 - 1.3e-08 34.9 0.1 7.9e-08 32.4 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KOS20679.1 - 9.4e-07 28.8 0.0 0.00018 21.5 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KOS20679.1 - 4.5e-06 26.5 0.3 8.1e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KOS20679.1 - 7.2e-05 22.3 0.0 9.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 KOS20679.1 - 0.00046 19.8 0.1 0.051 13.2 0.0 2.1 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 KOS20679.1 - 0.0015 18.1 0.1 0.08 12.4 0.0 2.1 1 1 1 2 2 2 1 Redoxin Thioredoxin_3 PF13192.1 KOS20679.1 - 0.0053 16.5 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin domain HyaE PF07449.6 KOS20679.1 - 0.015 15.1 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DIM1 PF02966.11 KOS20679.1 - 0.032 13.7 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_4 PF13462.1 KOS20679.1 - 0.033 14.1 0.0 4.5 7.2 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Glutaredoxin PF00462.19 KOS20679.1 - 0.082 12.9 0.1 0.18 11.8 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin DSBA PF01323.15 KOS20679.1 - 0.093 12.2 0.3 3.3 7.2 0.1 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF953 PF06110.6 KOS20679.1 - 0.1 12.0 0.0 0.36 10.2 0.0 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) NAGLU PF05089.7 KOS20680.1 - 6.1e-123 409.8 3.7 8.9e-123 409.2 2.5 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 KOS20680.1 - 4.7e-64 216.3 0.1 7.1e-64 215.7 0.1 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 KOS20680.1 - 8.2e-07 28.6 0.0 2.3e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Anoctamin PF04547.7 KOS20681.1 - 3.5e-104 348.9 6.0 4.3e-104 348.6 4.1 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel CcmH PF03918.9 KOS20681.1 - 0.09 11.7 0.0 0.09 11.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF3261 PF11659.3 KOS20681.1 - 0.15 11.6 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3261) CN_hydrolase PF00795.17 KOS20682.1 - 7e-10 38.5 0.0 1.4e-09 37.5 0.0 1.5 1 1 1 2 2 2 1 Carbon-nitrogen hydrolase DUF4079 PF13301.1 KOS20683.1 - 0.049 13.6 9.6 0.4 10.6 6.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF2427 PF10348.4 KOS20683.1 - 0.064 12.8 0.3 0.15 11.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) NIR_SIR PF01077.17 KOS20684.1 - 5.2e-53 178.6 0.1 1.4e-46 157.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KOS20684.1 - 1.2e-32 111.3 0.0 2.6e-16 58.9 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KOS20684.1 - 1.5e-27 96.3 0.0 3.3e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 KOS20684.1 - 1.5e-06 27.9 0.1 8.1e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.6 KOS20685.1 - 6.3e-48 162.9 0.7 8.1e-48 162.5 0.5 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 MARVEL PF01284.18 KOS20685.1 - 4.4 7.1 11.6 2.3 8.0 4.1 2.1 1 1 1 2 2 2 0 Membrane-associating domain SPC12 PF06645.8 KOS20685.1 - 5.7 6.8 7.3 0.68 9.7 1.3 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Mob1_phocein PF03637.12 KOS20686.1 - 7.3e-69 230.9 0.0 9.1e-69 230.6 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Chitin_synth_1 PF01644.12 KOS20687.1 - 2.8e-83 277.5 0.0 4.4e-83 276.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KOS20687.1 - 5.3e-32 109.3 0.1 1.2e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KOS20687.1 - 4.3e-25 88.1 2.5 5.2e-22 77.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KOS20687.1 - 9.2e-10 38.5 0.5 9.2e-10 38.5 0.3 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KOS20687.1 - 2.9e-06 27.2 0.0 5.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 ThiF PF00899.16 KOS20688.1 - 4.3e-11 42.7 0.0 1.7e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 ThiF family DUF1732 PF08340.6 KOS20688.1 - 0.0016 18.1 0.4 0.0064 16.3 0.1 2.1 2 0 0 2 2 1 1 Domain of unknown function (DUF1732) zf-RING_5 PF14634.1 KOS20688.1 - 0.03 14.0 0.6 0.067 12.9 0.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain MoeZ_MoeB PF05237.8 KOS20688.1 - 0.037 13.6 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 MoeZ/MoeB domain zf-RING_2 PF13639.1 KOS20688.1 - 0.054 13.3 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 KOS20688.1 - 0.082 12.5 0.3 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS20688.1 - 0.082 12.9 0.4 0.18 11.8 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fzo_mitofusin PF04799.8 KOS20688.1 - 0.092 12.1 1.4 0.18 11.1 1.0 1.5 1 0 0 1 1 1 0 fzo-like conserved region IncA PF04156.9 KOS20688.1 - 0.13 11.8 5.0 0.22 11.0 3.5 1.3 1 0 0 1 1 1 0 IncA protein zf-C3HC4_4 PF15227.1 KOS20688.1 - 0.14 12.0 0.4 0.31 10.9 0.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DivIVA PF05103.8 KOS20688.1 - 0.9 9.5 9.6 2 8.4 6.6 1.5 1 0 0 1 1 1 0 DivIVA protein APG6 PF04111.7 KOS20688.1 - 2 7.3 8.4 3.2 6.7 5.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 OmpH PF03938.9 KOS20688.1 - 7.4 6.4 14.0 15 5.5 9.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) adh_short PF00106.20 KOS20689.1 - 5.1e-36 124.1 0.2 8.3e-36 123.4 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS20689.1 - 1.2e-15 57.6 0.1 1.9e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KOS20689.1 - 7.5e-12 45.5 0.0 1e-11 45.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KOS20689.1 - 0.016 14.9 2.0 0.021 14.6 0.4 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KOS20689.1 - 0.062 12.1 0.0 0.41 9.5 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF1776 PF08643.5 KOS20689.1 - 0.078 12.1 0.0 0.39 9.8 0.0 2.0 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) RNA_pol_Rpb8 PF03870.10 KOS20690.1 - 2.7e-37 128.0 0.0 3e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 DUF775 PF05603.7 KOS20691.1 - 3.1e-46 157.4 0.0 5.8e-46 156.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF775) GDA1_CD39 PF01150.12 KOS20692.1 - 3.9e-98 328.8 0.0 5.2e-98 328.3 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family KA1 PF02149.14 KOS20692.1 - 0.18 11.2 0.0 0.44 10.0 0.0 1.6 1 0 0 1 1 1 0 Kinase associated domain 1 RNase_PH PF01138.16 KOS20693.1 - 1.3e-24 86.9 0.0 2.1e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 zf-C3HC4_3 PF13920.1 KOS20694.1 - 1.1e-06 28.2 16.0 1.8e-06 27.5 11.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SDA1 PF05285.7 KOS20694.1 - 0.0025 17.1 1.4 0.0037 16.6 1.0 1.2 1 0 0 1 1 1 1 SDA1 tRNA_int_endo PF01974.12 KOS20695.1 - 5.4e-12 45.3 0.0 1.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain PAXNEB PF05625.6 KOS20696.1 - 5.3e-79 265.6 0.0 5.9e-79 265.5 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein hDGE_amylase PF14701.1 KOS20697.1 - 1.1e-174 581.3 0.0 1.4e-174 580.9 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KOS20697.1 - 4.9e-115 384.1 0.0 7.8e-115 383.5 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KOS20697.1 - 5.6e-85 284.6 0.0 8.7e-85 284.0 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KOS20697.1 - 2e-27 94.8 0.0 4.8e-27 93.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KOS20697.1 - 0.00039 19.8 0.1 0.51 9.6 0.0 2.4 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Dicty_REP PF05086.7 KOS20698.1 - 0.78 7.4 7.1 0.81 7.3 4.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MIP-T3 PF10243.4 KOS20698.1 - 5.3 5.3 12.9 6.9 5.0 9.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mucin PF01456.12 KOS20698.1 - 5.6 6.7 18.4 8.7 6.1 12.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_C48 PF02902.14 KOS20699.1 - 1.3e-17 64.1 0.0 3.7e-17 62.6 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain NTP_transferase PF00483.18 KOS20700.1 - 1.1e-27 96.8 0.0 2.3e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase MannoseP_isomer PF01050.13 KOS20700.1 - 4.9e-05 22.9 0.1 8.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase NTP_transf_3 PF12804.2 KOS20700.1 - 8.3e-05 22.7 0.1 0.00031 20.8 0.0 2.1 2 0 0 2 2 2 1 MobA-like NTP transferase domain DUF4200 PF13863.1 KOS20700.1 - 0.054 13.4 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) NAD_Gly3P_dh_N PF01210.18 KOS20701.1 - 1.3e-44 151.7 0.0 2.1e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KOS20701.1 - 3.2e-40 137.2 0.2 5.7e-40 136.4 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 KOS20701.1 - 0.063 13.7 0.6 13 6.3 0.0 2.7 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Pox_VLTF3 PF04947.9 KOS20701.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Chromo PF00385.19 KOS20702.1 - 2.2e-07 30.4 1.5 3.3e-05 23.4 0.1 3.1 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Pam17 PF08566.5 KOS20703.1 - 9.9e-63 210.9 0.0 1.4e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 ThiF PF00899.16 KOS20704.1 - 9.6e-41 138.7 0.1 1.5e-40 138.1 0.1 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KOS20704.1 - 8.5e-20 70.1 0.6 3.4e-17 61.8 0.2 2.6 3 0 0 3 3 3 2 MoeZ/MoeB domain Rhodanese PF00581.15 KOS20704.1 - 6.8e-11 42.5 0.0 1.3e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 KOS20704.1 - 0.0042 17.1 0.2 0.027 14.5 0.1 2.0 1 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KOS20704.1 - 0.12 12.6 0.0 0.4 10.9 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF1192 PF06698.6 KOS20704.1 - 1.7 8.4 5.1 3.7 7.4 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) SLX9 PF15341.1 KOS20705.1 - 3.3e-23 82.4 0.0 7.5e-23 81.2 0.0 1.6 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 RAP1 PF07218.6 KOS20705.1 - 8.2 4.3 5.4 11 4.0 3.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Phosducin PF02114.11 KOS20706.1 - 2e-11 43.1 0.0 2.9e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 KOS20706.1 - 0.034 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin adh_short PF00106.20 KOS20707.1 - 6.2e-25 88.0 0.4 7.7e-25 87.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS20707.1 - 1.1e-11 44.9 0.0 1.5e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS20707.1 - 3.2e-06 26.9 0.2 5.1e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KOS20707.1 - 1.8e-05 24.8 0.1 2.6e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KOS20707.1 - 0.00066 19.1 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KdpC PF02669.10 KOS20707.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain DUF1776 PF08643.5 KOS20707.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Ferric_reduct PF01794.14 KOS20709.1 - 1e-17 64.4 6.4 1e-17 64.4 4.4 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KOS20709.1 - 1e-14 54.2 0.0 2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KOS20709.1 - 2.7e-14 53.3 0.0 5.9e-13 49.0 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KOS20709.1 - 0.0011 19.5 0.7 0.15 12.6 0.0 3.1 4 0 0 4 4 4 1 Oxidoreductase NAD-binding domain HMGL-like PF00682.14 KOS20710.1 - 4.5e-64 216.3 0.0 5.9e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KOS20710.1 - 2e-24 85.8 0.0 4e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain PFK PF00365.15 KOS20712.1 - 8.1e-164 543.3 0.3 4.2e-117 390.1 0.9 2.1 2 0 0 2 2 2 2 Phosphofructokinase TgMIC1 PF11476.3 KOS20712.1 - 0.55 9.7 2.5 1.5 8.3 0.1 2.6 3 0 0 3 3 3 0 Toxoplasma gondii micronemal protein 1 TgMIC1 UVR PF02151.14 KOS20712.1 - 2 8.0 5.0 0.42 10.1 0.6 2.0 2 0 0 2 2 2 0 UvrB/uvrC motif Med17 PF10156.4 KOS20713.1 - 2.1e-73 247.1 0.0 2.6e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex RNase_PH PF01138.16 KOS20714.1 - 5.9e-17 62.2 0.0 1.5e-16 60.9 0.0 1.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KOS20714.1 - 0.0057 16.5 0.0 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 GDI PF00996.13 KOS20715.1 - 2.7e-31 108.3 0.0 3.4e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Rad21_Rec8_N PF04825.8 KOS20716.1 - 7.3e-29 99.9 0.0 1.1e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KOS20716.1 - 6.3e-06 25.2 0.0 1.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF2283 PF10049.4 KOS20716.1 - 0.074 12.9 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) ScpA_ScpB PF02616.9 KOS20716.1 - 0.17 11.4 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 ScpA/B protein HEAT_EZ PF13513.1 KOS20717.1 - 1.9e-14 53.6 10.1 1.7e-07 31.5 0.0 8.5 8 2 0 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.1 KOS20717.1 - 5.8e-12 45.7 17.4 6e-05 23.2 0.0 7.7 3 1 3 7 7 7 4 HEAT repeats IBN_N PF03810.14 KOS20717.1 - 3.1e-11 43.0 3.8 2.7e-09 36.7 0.4 4.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.17 KOS20717.1 - 6.3e-11 41.4 17.7 0.013 15.4 0.0 10.4 13 0 0 13 13 13 3 HEAT repeat RIX1 PF08167.7 KOS20717.1 - 2.3e-05 24.1 0.8 4.2 7.0 0.2 5.2 2 1 1 3 3 3 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 KOS20717.1 - 3.3e-05 23.3 2.8 0.29 10.4 0.0 5.3 5 1 2 7 7 7 2 CLASP N terminal Xpo1 PF08389.7 KOS20717.1 - 0.00071 19.5 7.7 0.27 11.1 0.0 6.1 4 2 2 6 6 6 1 Exportin 1-like protein Arm PF00514.18 KOS20717.1 - 0.53 10.2 6.9 12 5.8 0.0 4.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat OB_NTP_bind PF07717.11 KOS20718.1 - 0.025 14.3 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold Methyltransf_2 PF00891.13 KOS20719.1 - 7.2e-34 117.0 0.0 8.9e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KOS20719.1 - 0.00033 20.4 0.0 0.00063 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 KOS20719.1 - 0.0056 16.4 0.0 0.016 14.9 0.0 1.9 1 0 0 1 1 1 1 Dimerisation domain Ribosomal_L22 PF00237.14 KOS20720.1 - 5.7e-15 55.1 0.1 1.2e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e adh_short PF00106.20 KOS20722.1 - 5.8e-23 81.6 4.4 7.5e-23 81.2 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS20722.1 - 2.3e-20 73.3 0.0 2.8e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS20722.1 - 3.1e-07 30.2 2.1 4.9e-07 29.5 1.4 1.2 1 0 0 1 1 1 1 KR domain LCE PF14672.1 KOS20723.1 - 5.5 7.5 13.0 2.1 8.8 2.1 2.2 1 1 1 2 2 2 0 Late cornified envelope CPL PF08144.6 KOS20724.1 - 9e-21 74.2 0.0 4e-20 72.1 0.0 2.2 1 0 0 1 1 1 1 CPL (NUC119) domain TraH_2 PF06871.6 KOS20724.1 - 0.55 9.6 7.3 0.13 11.6 0.2 2.8 3 0 0 3 3 3 0 TraH_2 RNA_pol_Rpb4 PF03874.11 KOS20725.1 - 1e-28 99.6 4.2 1.2e-28 99.4 2.9 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Spexin PF15171.1 KOS20725.1 - 0.11 12.5 1.4 0.15 12.0 0.2 1.8 2 0 0 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin Sybindin PF04099.7 KOS20726.1 - 2.7e-53 179.5 0.0 3.1e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KOS20726.1 - 4.7e-08 32.9 0.0 7.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region SNO PF01174.14 KOS20727.1 - 9.6e-54 181.8 0.0 2.5e-51 173.9 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 KOS20727.1 - 2.4e-10 40.2 0.0 3.2e-08 33.3 0.0 2.1 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 KOS20727.1 - 0.0002 20.8 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 KOS20727.1 - 0.00054 19.4 0.0 0.46 9.9 0.0 2.0 2 0 0 2 2 2 2 Glutamine amidotransferase class-I DUF4066 PF13278.1 KOS20727.1 - 0.00079 18.7 0.1 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_S51 PF03575.12 KOS20727.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 SOR_SNZ PF01680.12 KOS20728.1 - 6.4e-102 339.5 7.8 9.6e-102 338.9 5.4 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 KOS20728.1 - 3.6e-09 36.0 5.4 1.1e-07 31.1 0.2 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 KOS20728.1 - 0.0011 17.8 1.0 0.5 9.1 0.0 2.4 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) IGPS PF00218.16 KOS20728.1 - 0.0013 17.8 0.1 0.0039 16.2 0.0 1.9 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.16 KOS20728.1 - 0.0015 17.8 0.3 0.026 13.7 0.0 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.9 KOS20728.1 - 0.0055 15.6 1.9 0.11 11.5 0.0 3.1 2 2 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.19 KOS20728.1 - 0.017 14.5 0.2 0.019 14.3 0.1 1.3 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TMP-TENI PF02581.12 KOS20728.1 - 0.046 12.8 0.8 0.58 9.2 0.0 2.6 2 1 0 2 2 2 0 Thiamine monophosphate synthase/TENI NMO PF03060.10 KOS20728.1 - 3.1 6.8 11.3 0.45 9.6 2.2 2.7 2 2 0 2 2 2 0 Nitronate monooxygenase Glyco_hyd_65N_2 PF14498.1 KOS20729.1 - 3.5e-55 187.2 0.0 5.2e-55 186.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.10 KOS20729.1 - 0.071 11.7 0.1 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain PI3_PI4_kinase PF00454.22 KOS20730.1 - 4.2e-47 160.5 0.0 6.5e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KOS20730.1 - 4.9e-35 121.1 4.3 6.9e-35 120.6 3.0 1.2 1 0 0 1 1 1 1 FAT domain FATC PF02260.15 KOS20730.1 - 2.5e-19 68.3 0.0 5.5e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.1 KOS20730.1 - 0.011 16.0 0.2 0.011 16.0 0.1 2.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KOS20730.1 - 2.8 8.8 8.9 8.8 7.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat AIG2 PF06094.7 KOS20731.1 - 5.1e-10 39.7 0.0 7e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 KOS20731.1 - 2.9e-06 27.3 0.2 6.9e-05 22.8 0.1 2.8 2 1 0 2 2 2 1 AIG2-like family Pyridox_oxidase PF01243.15 KOS20732.1 - 4.7e-12 45.7 0.1 1.2e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4526 PF15029.1 KOS20732.1 - 0.45 10.0 2.6 0.82 9.1 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) DUF2076 PF09849.4 KOS20732.1 - 3 7.8 11.7 4.5 7.2 8.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CDC45 PF02724.9 KOS20732.1 - 3.7 5.4 6.7 5.1 4.9 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 KOS20732.1 - 8.1 5.0 17.5 12 4.4 12.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Mem_trans PF03547.13 KOS20733.1 - 4e-53 180.0 0.2 5.3e-53 179.7 0.1 1.2 1 0 0 1 1 1 1 Membrane transport protein Amidoligase_2 PF12224.3 KOS20734.1 - 6.2e-18 65.3 0.0 9.9e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme CPSase_L_D2 PF02786.12 KOS20735.1 - 1.9e-72 242.9 0.0 4.4e-72 241.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KOS20735.1 - 3.5e-34 117.0 0.0 1.2e-33 115.2 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KOS20735.1 - 1.2e-31 109.0 0.1 2.3e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KOS20735.1 - 1.2e-19 70.7 0.3 3.2e-19 69.3 0.1 1.8 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KOS20735.1 - 1e-16 60.3 0.5 2.5e-16 59.0 0.4 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KOS20735.1 - 1.4e-15 56.9 0.0 2.5e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KOS20735.1 - 2.1e-10 40.0 0.0 0.00014 21.4 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KOS20735.1 - 3.6e-07 29.7 0.0 9.2e-07 28.4 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KOS20735.1 - 4.4e-07 29.4 0.0 8.3e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 KOS20735.1 - 8.4e-05 22.0 0.0 0.099 11.9 0.0 2.8 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 KOS20735.1 - 0.00061 20.0 0.0 1.2 9.5 0.0 2.9 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 KOS20735.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 KOS20735.1 - 0.05 12.7 0.0 3.6 6.6 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.14 KOS20735.1 - 0.062 12.9 0.2 0.37 10.4 0.1 2.2 2 0 0 2 2 2 0 Glycine cleavage H-protein Serglycin PF04360.7 KOS20735.1 - 0.083 12.6 0.6 0.17 11.6 0.4 1.4 1 0 0 1 1 1 0 Serglycin BPL_LplA_LipB PF03099.14 KOS20736.1 - 4.4e-07 29.9 0.0 7.9e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Biotin/lipoate A/B protein ligase family SelP_N PF04592.9 KOS20736.1 - 0.29 10.4 8.1 0.18 11.1 3.7 1.8 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Trypan_PARP PF05887.6 KOS20736.1 - 0.98 9.2 5.2 1.9 8.2 3.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2360 PF10152.4 KOS20736.1 - 1.2 9.3 12.1 2.7 8.2 1.6 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) APC_CDC26 PF10471.4 KOS20736.1 - 8.1 7.2 14.4 0.64 10.7 0.7 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Glyco_hydro_18 PF00704.23 KOS20737.1 - 2.8e-14 53.3 1.2 7.5e-14 51.9 0.8 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Ustilago_mating PF05722.7 KOS20737.1 - 0.34 10.1 6.8 0.59 9.4 4.7 1.3 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Pkinase PF00069.20 KOS20738.1 - 5.9e-49 166.5 0.0 6.4e-46 156.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KOS20738.1 - 4.3e-29 101.3 0.0 9.8e-28 96.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 KOS20738.1 - 0.00014 20.8 0.1 0.00065 18.6 0.1 1.8 2 0 0 2 2 2 1 Seadornavirus VP7 Kinase-like PF14531.1 KOS20738.1 - 0.017 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Amidase02_C PF12123.3 KOS20738.1 - 0.16 11.6 0.1 4.7 6.9 0.1 2.5 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase SUR7 PF06687.7 KOS20739.1 - 4.6e-23 81.9 0.9 6.2e-23 81.4 0.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KOS20739.1 - 0.0023 17.6 11.0 0.0025 17.5 6.2 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 KOS20739.1 - 0.041 13.1 1.1 0.063 12.5 0.8 1.2 1 0 0 1 1 1 0 Clc-like DUF4658 PF15555.1 KOS20739.1 - 0.42 10.4 2.2 1.3 8.9 1.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Form-deh_trans PF09163.6 KOS20739.1 - 5.2 6.6 8.6 3.2 7.3 3.5 2.3 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane DUF3602 PF12223.3 KOS20740.1 - 5.6e-16 58.7 9.2 1e-11 45.0 1.4 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.17 KOS20740.1 - 0.59 9.7 5.2 13 5.4 0.0 3.0 1 1 1 3 3 3 0 GTP1/OBG HisG PF01634.13 KOS20741.1 - 6.1e-36 123.4 0.2 2e-35 121.7 0.1 1.9 1 1 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 KOS20741.1 - 9.9e-28 95.9 0.2 2.9e-27 94.4 0.2 1.8 1 0 0 1 1 1 1 HisG, C-terminal domain RE_Eco29kI PF09517.5 KOS20741.1 - 0.0098 15.2 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 2 Eco29kI restriction endonuclease Complex1_LYR PF05347.10 KOS20742.1 - 2.1e-09 37.0 0.1 3.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KOS20742.1 - 4.8e-09 36.2 0.2 9.1e-09 35.4 0.1 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KOS20742.1 - 1.6e-05 25.3 0.5 2.9e-05 24.4 0.3 1.6 1 1 0 1 1 1 1 Complex1_LYR-like HA2 PF04408.18 KOS20743.1 - 2.3e-16 59.6 0.0 5.2e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KOS20743.1 - 9e-16 57.7 0.1 2.1e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KOS20743.1 - 2.1e-13 49.8 0.0 4.4e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS20743.1 - 1.2e-06 28.1 0.0 4.9e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KOS20743.1 - 3.1e-05 24.1 0.0 6.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS20743.1 - 0.0013 18.8 0.6 0.0037 17.2 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KOS20743.1 - 0.0018 17.7 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 KOS20743.1 - 0.0027 16.8 0.0 0.0062 15.6 0.0 1.6 1 0 0 1 1 1 1 KaiC ABC_tran PF00005.22 KOS20743.1 - 0.021 15.1 0.0 0.072 13.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.15 KOS20743.1 - 0.034 12.8 1.2 0.061 12.0 0.8 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_23 PF13476.1 KOS20743.1 - 0.098 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF386 PF04074.7 KOS20743.1 - 0.13 11.7 0.1 0.55 9.7 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF386) ING PF12998.2 KOS20744.1 - 7.3e-21 74.4 3.0 1.1e-20 73.8 2.1 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KOS20744.1 - 2.4e-08 33.5 9.6 4.1e-08 32.8 6.6 1.4 1 0 0 1 1 1 1 PHD-finger Axin_b-cat_bind PF08833.5 KOS20744.1 - 0.062 13.0 0.1 14 5.5 0.0 3.7 3 0 0 3 3 3 0 Axin beta-catenin binding domain Methyltransf_16 PF10294.4 KOS20745.1 - 0.0034 16.8 0.0 0.0093 15.4 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 KOS20745.1 - 0.018 15.6 0.0 0.081 13.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain ADSL_C PF10397.4 KOS20745.1 - 0.02 14.9 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus Methyltransf_26 PF13659.1 KOS20745.1 - 0.042 13.8 0.1 0.1 12.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KOS20745.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Rab5ip PF07019.7 KOS20746.1 - 2.8e-21 75.4 5.2 3.9e-21 74.9 3.6 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) BCLP PF12304.3 KOS20746.1 - 0.048 13.0 0.7 5.6 6.3 0.0 2.2 1 1 1 2 2 2 0 Beta-casein like protein URO-D PF01208.12 KOS20747.1 - 7.8e-113 376.8 0.0 8.7e-113 376.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) SNARE PF05739.14 KOS20748.1 - 3.7e-06 26.5 6.4 3.7e-06 26.5 4.4 2.3 2 0 0 2 2 2 1 SNARE domain V-SNARE_C PF12352.3 KOS20748.1 - 0.019 14.9 6.0 0.092 12.8 1.0 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus RRM_1 PF00076.17 KOS20750.1 - 6.9e-49 163.3 0.0 3.9e-17 61.6 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS20750.1 - 4.4e-42 141.9 0.0 1.1e-13 50.9 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS20750.1 - 1.6e-26 91.8 0.0 2.8e-13 49.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KOS20750.1 - 4.7e-11 42.2 0.0 0.00029 20.5 0.0 3.8 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 KOS20750.1 - 0.0086 15.4 0.0 0.021 14.2 0.0 1.7 1 0 0 1 1 1 1 Lsm interaction motif RRM_3 PF08777.6 KOS20750.1 - 0.0088 15.8 0.2 0.13 12.1 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM PF05172.8 KOS20750.1 - 0.14 11.9 0.0 1.4 8.7 0.0 2.6 2 1 1 3 3 3 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KOS20750.1 - 0.74 9.6 4.5 3.4 7.4 0.0 3.9 4 1 1 5 5 5 0 Limkain b1 TMEM154 PF15102.1 KOS20751.1 - 0.0022 17.6 0.1 0.0073 16.0 0.0 1.9 1 1 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.1 KOS20751.1 - 0.005 17.2 0.0 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 KOS20751.1 - 0.021 14.1 1.8 0.044 13.1 1.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Herpes_gE PF02480.11 KOS20751.1 - 0.026 12.8 0.0 0.055 11.7 0.0 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Podoplanin PF05808.6 KOS20751.1 - 0.036 13.6 9.6 0.029 13.9 2.8 2.2 1 1 0 2 2 2 0 Podoplanin DUF1191 PF06697.7 KOS20751.1 - 0.045 12.5 0.0 0.06 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) MCPVI PF02993.9 KOS20751.1 - 1.9 8.5 5.4 3 7.9 3.3 1.5 2 0 0 2 2 2 0 Minor capsid protein VI Shisa PF13908.1 KOS20751.1 - 3.2 7.8 15.8 9.2 6.3 5.1 3.2 1 1 2 3 3 3 0 Wnt and FGF inhibitory regulator Beta-APP PF03494.8 KOS20751.1 - 3.4 7.2 6.1 1.2 8.6 1.8 1.9 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) Fungal_trans_2 PF11951.3 KOS20752.1 - 1.4e-26 93.0 0.1 1.7e-26 92.7 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS20752.1 - 5.2e-07 29.4 9.1 1.1e-06 28.4 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KOS20753.1 - 7.7e-10 38.5 10.3 0.00017 21.7 0.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KOS20753.1 - 3.4e-08 33.3 7.4 2.9e-07 30.4 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KOS20753.1 - 3.1e-05 23.9 12.4 0.0015 18.6 0.6 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KOS20753.1 - 0.021 15.0 5.4 0.024 14.8 1.0 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KOS20753.1 - 0.021 14.9 5.8 0.041 14.0 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KOS20753.1 - 0.96 9.4 4.6 7.4 6.6 0.2 2.7 3 0 0 3 3 3 0 Zinc ribbon domain zf-BED PF02892.10 KOS20753.1 - 2.3 8.0 8.7 13 5.6 0.9 2.6 1 1 1 2 2 2 0 BED zinc finger Pkinase PF00069.20 KOS20755.1 - 7.6e-60 202.2 0.2 1.4e-59 201.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS20755.1 - 4.3e-38 130.8 0.0 1.2e-37 129.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS20755.1 - 4.8e-05 22.4 0.0 0.0001 21.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like NCA2 PF08637.5 KOS20755.1 - 0.0014 17.6 0.1 0.0081 15.0 0.0 2.1 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Serglycin PF04360.7 KOS20755.1 - 0.027 14.2 2.9 0.066 12.9 2.0 1.6 1 0 0 1 1 1 0 Serglycin Corona_S2 PF01601.11 KOS20755.1 - 0.16 10.0 0.1 0.25 9.3 0.1 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein PolyA_pol PF01743.15 KOS20755.1 - 1.5 9.0 4.5 2 8.6 2.2 1.9 1 1 0 1 1 1 0 Poly A polymerase head domain APH PF01636.18 KOS20755.1 - 3.4 7.3 7.1 0.59 9.8 0.0 2.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family BAF1_ABF1 PF04684.8 KOS20755.1 - 3.8 6.2 17.1 1 8.1 5.2 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor BTB PF00651.26 KOS20756.1 - 8.6e-23 80.4 0.0 2.8e-11 43.3 0.1 2.7 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.2 KOS20756.1 - 3.5e-07 30.4 0.0 1.5e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KOS20756.1 - 1.5e-06 28.1 0.0 1.5e-05 25.0 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KOS20756.1 - 2.5e-06 27.0 0.2 1e-05 25.1 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 KOS20756.1 - 7.8e-06 26.2 0.1 2.8e-05 24.4 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS20756.1 - 0.00041 20.3 1.0 0.0065 16.5 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Choline_kinase PF01633.15 KOS20757.1 - 1.7e-57 194.4 0.0 2.8e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 KOS20757.1 - 4.2e-17 61.3 0.1 8.3e-17 60.4 0.1 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 KOS20757.1 - 9.4e-08 32.0 0.2 9.4e-08 32.0 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Hydrolase_6 PF13344.1 KOS20758.1 - 6.9e-19 67.6 0.0 1.6e-18 66.4 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KOS20758.1 - 9.1e-16 57.3 0.0 2.7e-15 55.8 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KOS20758.1 - 0.00012 22.6 0.0 2.1 8.7 0.0 3.2 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KOS20758.1 - 0.013 15.7 0.0 0.64 10.2 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HET PF06985.6 KOS20759.1 - 7.8e-29 100.6 1.2 1.6e-28 99.6 0.8 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Alpha_adaptin_C PF02296.11 KOS20759.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain EST1_DNA_bind PF10373.4 KOS20760.1 - 1e-18 67.5 0.3 2.2e-18 66.4 0.0 1.6 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain DUF4632 PF15451.1 KOS20760.1 - 0.087 12.7 2.1 4 7.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) DUF3439 PF11921.3 KOS20760.1 - 1.9 8.2 9.4 4.9 6.9 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_18 PF00704.23 KOS20761.1 - 1e-32 113.9 0.0 5e-32 111.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 KOS20761.1 - 7.5e-05 22.0 0.0 0.0001 21.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 DUF4470 PF14737.1 KOS20762.1 - 0.00095 18.8 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Ripply PF14998.1 KOS20762.1 - 1.9 8.6 5.1 0.59 10.2 0.4 2.5 3 0 0 3 3 3 0 Transcription Regulator CRCB PF02537.10 KOS20763.1 - 6.8e-32 109.7 22.9 4.8e-21 74.8 5.3 3.5 4 0 0 4 4 4 3 CrcB-like protein GMC_oxred_N PF00732.14 KOS20764.1 - 2.7e-48 164.6 0.0 3.6e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KOS20764.1 - 5.8e-28 97.9 0.0 1.4e-27 96.7 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KOS20764.1 - 6.8e-09 35.0 0.6 1.2e-07 30.9 0.4 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KOS20764.1 - 3.9e-05 22.7 0.0 7.1e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KOS20764.1 - 0.00038 20.4 0.0 0.0014 18.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KOS20764.1 - 0.00043 20.2 0.1 0.0016 18.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KOS20764.1 - 0.0034 16.3 0.0 0.45 9.3 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KOS20764.1 - 0.006 16.3 0.2 0.032 14.0 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KOS20764.1 - 0.01 14.9 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KOS20764.1 - 0.015 14.1 1.6 0.14 11.0 0.1 2.3 2 1 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 KOS20764.1 - 0.016 13.6 0.1 0.069 11.6 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 KOS20764.1 - 0.074 13.1 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LigB PF02900.13 KOS20765.1 - 4.1e-38 130.9 1.9 5.8e-38 130.4 1.3 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Amidohydro_4 PF13147.1 KOS20766.1 - 6.5e-13 49.3 7.3 1.5e-12 48.1 1.2 3.2 2 2 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 KOS20766.1 - 8.4e-09 35.5 1.8 2e-06 27.7 1.2 3.4 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KOS20766.1 - 1.1e-06 28.3 0.2 3.9e-06 26.5 0.2 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KOS20766.1 - 1.5e-05 24.4 0.0 1.5e-05 24.4 0.0 2.6 3 1 0 3 3 3 1 Amidohydrolase family CtsR PF05848.6 KOS20766.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Firmicute transcriptional repressor of class III stress genes (CtsR) GST_C_3 PF14497.1 KOS20767.1 - 0.0047 17.3 0.0 0.0097 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KOS20767.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KOS20767.1 - 0.029 14.3 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KOS20767.1 - 0.039 14.1 0.1 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Pneumo_att_G PF05539.6 KOS20767.1 - 0.88 8.8 5.3 1.2 8.4 3.7 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Methyltransf_12 PF08242.7 KOS20768.1 - 0.011 16.1 0.0 0.055 13.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain NUDIX PF00293.23 KOS20768.1 - 0.065 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 NUDIX domain Methyltransf_25 PF13649.1 KOS20768.1 - 0.11 12.9 0.8 0.52 10.6 0.5 2.2 1 1 0 1 1 1 0 Methyltransferase domain FA_desaturase PF00487.19 KOS20769.1 - 6.3e-11 42.1 31.5 6.3e-11 42.1 21.9 2.1 1 1 1 2 2 2 1 Fatty acid desaturase MIP PF00230.15 KOS20770.1 - 2.9e-31 108.6 7.2 4.5e-31 108.0 5.0 1.2 1 0 0 1 1 1 1 Major intrinsic protein Pyr_redox_3 PF13738.1 KOS20772.1 - 6.7e-21 75.2 0.0 1.8e-20 73.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KOS20772.1 - 0.00016 19.9 0.0 0.0012 17.1 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KOS20772.1 - 0.001 19.0 0.0 0.0035 17.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KOS20772.1 - 0.0029 16.5 0.0 0.12 11.2 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KOS20772.1 - 0.016 14.9 0.0 1.1 8.9 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KOS20772.1 - 0.05 13.7 0.0 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KOS20772.1 - 0.062 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ecm29 PF13001.2 KOS20773.1 - 2.3e-80 270.5 1.4 3.9e-80 269.7 0.2 1.9 2 0 0 2 2 2 1 Proteasome stabiliser HEAT_EZ PF13513.1 KOS20773.1 - 0.00083 19.7 3.3 5.6 7.5 0.0 7.5 8 0 0 8 8 8 1 HEAT-like repeat HEAT PF02985.17 KOS20773.1 - 2.8 8.2 16.7 91 3.5 0.1 8.1 10 0 0 10 10 10 0 HEAT repeat RRM_1 PF00076.17 KOS20774.1 - 2.4e-45 151.9 0.0 1.3e-16 59.9 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS20774.1 - 6.1e-25 87.0 0.0 5e-10 39.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS20774.1 - 1.8e-21 75.6 0.0 1.1e-08 34.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KOS20774.1 - 5.1e-07 29.3 0.1 0.0028 17.3 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KOS20774.1 - 1.2e-05 25.0 0.0 0.00012 21.8 0.0 2.4 3 0 0 3 3 3 1 RNA binding motif Thioredoxin_7 PF13899.1 KOS20775.1 - 1.7e-13 50.4 0.1 3.7e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 KOS20775.1 - 6e-11 41.7 0.0 1.3e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KOS20775.1 - 6.1e-05 23.0 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.10 KOS20775.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 KOS20775.1 - 0.021 14.9 0.1 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain DUF2457 PF10446.4 KOS20775.1 - 0.24 10.0 10.6 2.9 6.5 8.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Iso_dh PF00180.15 KOS20776.1 - 7.7e-81 271.7 0.0 9.4e-81 271.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RC-P840_PscD PF10657.4 KOS20776.1 - 0.15 11.9 0.0 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 Photosystem P840 reaction centre protein PscD zf-H2C2_2 PF13465.1 KOS20777.1 - 1e-14 53.9 9.4 3.5e-08 33.3 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KOS20777.1 - 3.3e-13 49.1 12.1 5.4e-06 26.4 1.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS20777.1 - 1.6e-11 43.6 12.1 2.6e-05 24.2 1.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KOS20777.1 - 2.7e-08 33.6 1.6 0.02 15.0 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS20777.1 - 0.00015 21.8 6.0 0.0093 16.1 0.2 3.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KOS20777.1 - 0.086 12.9 2.1 0.16 12.1 1.5 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.1 KOS20777.1 - 0.42 10.9 2.1 0.33 11.2 0.2 1.8 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain LIM PF00412.17 KOS20777.1 - 0.75 9.9 5.7 4.7 7.3 2.8 2.8 2 1 1 3 3 3 0 LIM domain zf-C2H2_6 PF13912.1 KOS20777.1 - 0.83 9.6 10.5 7.3 6.6 0.4 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger FYVE PF01363.16 KOS20777.1 - 1.3 8.9 4.9 2.7 7.9 3.4 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-BED PF02892.10 KOS20777.1 - 4.9 6.9 5.5 9.1 6.1 0.7 2.5 1 1 1 2 2 2 0 BED zinc finger TMF_TATA_bd PF12325.3 KOS20778.1 - 3.6e-38 130.0 3.5 3.6e-38 130.0 2.4 5.8 3 1 0 5 5 5 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KOS20778.1 - 3e-11 42.9 11.6 3e-11 42.9 8.0 8.7 6 4 0 7 7 7 1 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KOS20778.1 - 0.8 8.8 11.7 0.2 10.8 0.1 3.1 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Ank_2 PF12796.2 KOS20779.1 - 2e-42 143.3 1.9 1.1e-14 54.4 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KOS20779.1 - 8.7e-39 129.4 0.9 6.4e-06 25.7 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KOS20779.1 - 9.7e-39 131.0 5.1 3.1e-09 37.1 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KOS20779.1 - 1e-33 114.6 6.0 7.2e-10 38.7 0.1 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS20779.1 - 1.1e-32 108.8 0.1 0.00072 19.5 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat WD40 PF00400.27 KOS20780.1 - 9.8e-55 180.5 18.7 1.4e-09 37.4 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KOS20780.1 - 0.00097 17.3 5.1 3.7 5.5 0.8 4.8 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KOS20780.1 - 0.013 14.9 0.4 8 5.8 0.0 2.8 2 1 0 2 2 2 0 PQQ-like domain Peroxidase_2 PF01328.12 KOS20781.1 - 1.6e-16 59.9 0.0 2.3e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 AAA PF00004.24 KOS20782.1 - 1.7e-14 54.1 0.0 3.6e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KOS20782.1 - 2.9e-11 43.7 0.0 2e-10 40.9 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain BAH PF01426.13 KOS20782.1 - 1.2e-09 37.9 0.0 2.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.1 KOS20782.1 - 1.4e-08 34.9 0.0 3.7e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS20782.1 - 0.00033 20.3 0.1 0.0012 18.5 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KOS20782.1 - 0.00053 20.8 0.0 0.0033 18.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zot PF05707.7 KOS20782.1 - 0.0015 17.9 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Arch_ATPase PF01637.13 KOS20782.1 - 0.0017 18.1 0.0 0.015 14.9 0.0 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 KOS20782.1 - 0.0044 17.3 0.0 0.0096 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KOS20782.1 - 0.0083 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KOS20782.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KOS20782.1 - 0.015 14.9 0.0 0.038 13.6 0.0 1.7 1 1 0 1 1 1 0 NACHT domain DUF815 PF05673.8 KOS20782.1 - 0.022 13.7 0.0 4.8 6.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 KOS20782.1 - 0.041 13.8 0.1 0.1 12.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_32 PF13654.1 KOS20782.1 - 0.06 11.9 0.0 0.093 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 KOS20782.1 - 0.068 12.1 0.0 0.51 9.2 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 KOS20782.1 - 0.082 13.0 0.0 0.33 11.1 0.0 2.1 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 KOS20782.1 - 0.16 11.7 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 NTPase PIF1 PF05970.9 KOS20782.1 - 0.18 10.6 0.0 0.4 9.5 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase Prefoldin PF02996.12 KOS20783.1 - 8.2e-23 80.3 0.2 1.1e-22 79.9 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KOS20783.1 - 0.015 15.0 5.4 0.2 11.4 0.8 2.1 2 0 0 2 2 2 0 Prefoldin subunit Sec2p PF06428.6 KOS20783.1 - 0.03 14.1 9.5 0.079 12.8 0.6 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.5 KOS20783.1 - 0.047 13.8 1.6 2 8.5 0.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.1 KOS20783.1 - 0.049 12.8 4.1 0.88 8.7 0.4 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cep57_MT_bd PF06657.8 KOS20783.1 - 0.13 12.2 2.8 0.26 11.2 0.2 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 KxDL PF10241.4 KOS20783.1 - 0.15 11.9 2.9 2.5 8.0 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein TACC PF05010.9 KOS20783.1 - 0.27 10.9 5.2 4.1 7.1 1.3 2.0 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) HGTP_anticodon PF03129.15 KOS20784.1 - 4e-10 39.5 0.0 6.7e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain eIF3_subunit PF08597.5 KOS20785.1 - 1.5e-65 221.2 24.7 1.6e-65 221.0 17.1 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PRP4 PF08799.6 KOS20785.1 - 1.2 8.4 5.6 2.4 7.5 3.9 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DUF2992 PF11208.3 KOS20785.1 - 4.4 7.2 16.5 0.33 10.8 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Plasmodium_Vir PF05795.6 KOS20785.1 - 4.4 6.3 7.5 1.4 8.0 1.2 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein AOX PF01786.12 KOS20786.1 - 4.6e-78 261.3 0.2 5.7e-78 261.0 0.2 1.0 1 0 0 1 1 1 1 Alternative oxidase IMD PF08397.6 KOS20787.1 - 6.2e-05 22.4 0.5 0.0057 15.9 0.0 2.1 2 0 0 2 2 2 2 IRSp53/MIM homology domain TFIIA PF03153.8 KOS20787.1 - 0.0074 16.2 0.9 0.0091 15.9 0.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Prothymosin PF03247.9 KOS20787.1 - 0.4 10.8 21.1 0.9 9.7 14.6 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family Nop14 PF04147.7 KOS20787.1 - 0.52 8.1 8.9 0.69 7.7 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KOS20787.1 - 6.3 5.1 16.7 9.4 4.5 11.6 1.2 1 0 0 1 1 1 0 Daxx Family Arb2 PF09757.4 KOS20789.1 - 4.2e-19 68.6 0.0 6.3e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain ThiF PF00899.16 KOS20791.1 - 2.7e-33 114.6 0.0 4.7e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 KOS20791.1 - 0.0097 15.9 0.1 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.11 KOS20791.1 - 0.018 14.4 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.19 KOS20791.1 - 0.026 13.4 0.3 0.044 12.6 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ldh_1_N PF00056.18 KOS20791.1 - 0.055 13.2 0.1 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KOS20791.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KOS20791.1 - 0.07 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 KOS20791.1 - 0.085 11.8 0.3 0.27 10.1 0.2 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase Glyco_hydro_17 PF00332.13 KOS20791.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 TPR_12 PF13424.1 KOS20792.1 - 2.9e-05 23.9 0.2 0.12 12.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat SR-25 PF10500.4 KOS20792.1 - 0.00044 19.8 13.5 0.00044 19.8 9.3 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein TPR_14 PF13428.1 KOS20792.1 - 0.0092 16.5 3.9 11 7.0 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat ATG16 PF08614.6 KOS20792.1 - 0.018 14.8 1.6 0.031 14.1 1.1 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Pacs-1 PF10254.4 KOS20792.1 - 0.02 13.5 4.3 0.035 12.7 3.0 1.3 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Macoilin PF09726.4 KOS20792.1 - 0.094 10.9 6.9 0.14 10.3 4.8 1.2 1 0 0 1 1 1 0 Transmembrane protein NAM-associated PF14303.1 KOS20792.1 - 0.21 11.9 3.1 0.35 11.1 2.2 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF737 PF05300.6 KOS20792.1 - 0.47 10.3 5.3 1.4 8.8 3.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF737) TPR_11 PF13414.1 KOS20793.1 - 6.5e-11 41.7 2.1 1.1e-06 28.2 0.0 4.5 3 1 1 4 4 4 1 TPR repeat TPR_2 PF07719.12 KOS20793.1 - 1.1e-06 28.0 10.0 0.0039 17.0 0.0 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KOS20793.1 - 5.4e-06 26.2 4.8 0.11 12.4 0.1 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KOS20793.1 - 5.1e-05 23.8 33.3 0.0067 17.0 0.1 7.4 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 KOS20793.1 - 8.1e-05 22.0 0.0 0.082 12.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KOS20793.1 - 0.00028 21.1 6.3 0.82 10.0 0.0 5.5 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 KOS20793.1 - 0.00042 20.7 19.5 15 6.5 0.0 8.1 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS20793.1 - 0.0033 17.1 0.1 1 9.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KOS20793.1 - 0.021 15.0 0.4 1.6e+02 2.8 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat QRPTase_C PF01729.14 KOS20794.1 - 2.9e-53 179.8 0.1 3.6e-53 179.5 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KOS20794.1 - 2.7e-19 68.7 0.0 8.1e-19 67.2 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Sugar_tr PF00083.19 KOS20795.1 - 1.1e-73 248.3 23.7 1.3e-73 248.1 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS20795.1 - 1.1e-15 57.2 31.8 1.1e-15 57.2 22.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KOS20796.1 - 4e-17 62.3 0.6 5.4e-17 61.8 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KOS20796.1 - 1.1e-07 31.1 0.0 0.0012 17.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KOS20796.1 - 0.00031 20.7 0.1 0.00073 19.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KOS20796.1 - 0.0014 19.0 0.0 0.016 15.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KOS20796.1 - 0.0071 15.2 0.0 1 8.1 0.0 2.7 1 1 2 3 3 3 2 FAD binding domain NAD_binding_9 PF13454.1 KOS20796.1 - 0.0075 16.0 0.0 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KOS20796.1 - 0.037 12.6 0.5 0.27 9.8 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.7 KOS20796.1 - 0.061 12.2 0.0 0.94 8.3 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 KOS20796.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RabGAP-TBC PF00566.13 KOS20797.1 - 2.6e-32 112.0 0.0 1.2e-31 109.8 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Sulfate_transp PF00916.15 KOS20798.1 - 8.3e-74 248.0 11.3 1.4e-73 247.3 7.8 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KOS20798.1 - 6.2e-31 105.9 4.3 6.2e-31 105.9 3.0 3.7 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KOS20798.1 - 3.9e-08 32.7 0.0 7.7e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain FimP PF09766.4 KOS20799.1 - 6.3e-27 94.5 12.2 8.1e-27 94.2 8.5 1.1 1 0 0 1 1 1 1 Fms-interacting protein TSC22 PF01166.13 KOS20799.1 - 0.037 13.9 4.8 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.4 KOS20799.1 - 0.038 13.8 11.5 1.2 8.9 3.4 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 K-box PF01486.12 KOS20799.1 - 0.2 11.4 16.7 0.18 11.5 8.0 3.1 1 1 0 2 2 2 0 K-box region Pinin_SDK_memA PF04696.8 KOS20799.1 - 0.2 11.2 11.9 0.65 9.6 4.1 2.3 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Toxin_8 PF07365.7 KOS20799.1 - 0.55 10.2 3.0 0.51 10.3 0.7 2.0 2 0 0 2 2 2 0 Alpha conotoxin precursor DUF4200 PF13863.1 KOS20799.1 - 0.94 9.4 18.8 0.28 11.1 1.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Rrp15p PF07890.7 KOS20799.1 - 3.7 7.5 8.7 0.31 11.1 0.7 2.3 2 1 0 2 2 2 0 Rrp15p Aldedh PF00171.17 KOS20799.1 - 4.9 5.3 6.4 0.39 8.9 0.6 1.7 2 0 0 2 2 2 0 Aldehyde dehydrogenase family HlyIII PF03006.15 KOS20800.1 - 9.8e-54 182.0 23.0 1.2e-53 181.7 15.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related HATPase_c_2 PF13581.1 KOS20800.1 - 0.098 12.4 1.8 0.28 10.9 1.0 1.8 1 1 1 2 2 2 0 Histidine kinase-like ATPase domain SPC12 PF06645.8 KOS20800.1 - 0.7 9.7 4.7 0.13 12.1 0.2 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) MOSC PF03473.12 KOS20801.1 - 2.3e-20 72.4 0.3 4.2e-20 71.5 0.0 1.5 2 0 0 2 2 2 1 MOSC domain ARS2 PF04959.8 KOS20802.1 - 2.2e-06 28.0 3.7 2.8e-06 27.6 2.6 1.1 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF629 PF04780.7 KOS20802.1 - 0.04 12.4 0.9 0.046 12.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Hormone_3 PF00159.13 KOS20802.1 - 0.13 12.2 0.2 0.62 10.1 0.0 2.0 2 0 0 2 2 2 0 Pancreatic hormone peptide RRM_1 PF00076.17 KOS20803.1 - 7.3e-17 60.7 0.1 1.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS20803.1 - 6.1e-12 45.3 0.0 1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS20803.1 - 0.00019 21.1 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KOS20803.1 - 0.088 12.3 0.3 0.2 11.1 0.2 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain Med15 PF09606.5 KOS20803.1 - 0.66 8.1 30.9 0.95 7.5 21.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SWI-SNF_Ssr4 PF08549.5 KOS20804.1 - 2e-185 617.9 17.7 7.8e-185 616.0 12.3 1.7 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Metal_resist PF13801.1 KOS20804.1 - 0.14 12.1 0.2 0.14 12.1 0.1 3.0 3 0 0 3 3 3 0 Heavy-metal resistance WLM PF08325.5 KOS20805.1 - 5.2e-50 169.9 0.0 1.5e-49 168.4 0.0 1.7 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 KOS20805.1 - 4e-07 30.0 0.2 7.2e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF45 Daxx PF03344.10 KOS20805.1 - 1.2 7.4 6.0 1.6 7.1 4.2 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KOS20805.1 - 4.4 5.1 10.6 5.3 4.8 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family Fungal_trans PF04082.13 KOS20806.1 - 1.4e-05 24.1 0.0 3.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS20806.1 - 2.5e-05 24.0 11.9 5.2e-05 23.0 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 KOS20807.1 - 5.3e-24 85.4 0.0 7.3e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KOS20807.1 - 6.6e-07 28.5 0.2 0.00016 20.6 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KOS20807.1 - 1.5e-06 28.0 0.3 0.00067 19.4 0.6 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding PMT_C PF11647.3 KOS20807.1 - 0.03 13.9 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Fungal_trans PF04082.13 KOS20808.1 - 2e-12 46.5 0.1 3.2e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Wzy_C PF04932.10 KOS20808.1 - 0.067 12.9 3.0 0.31 10.8 2.5 1.7 2 0 0 2 2 2 0 O-Antigen ligase gpUL132 PF11359.3 KOS20808.1 - 1.3 8.2 4.9 3 7.1 3.4 1.5 1 0 0 1 1 1 0 Glycoprotein UL132 TMEM154 PF15102.1 KOS20808.1 - 4.8 6.8 6.1 14 5.3 4.2 1.8 1 0 0 1 1 1 0 TMEM154 protein family DUF3796 PF12676.2 KOS20808.1 - 6.4 7.0 6.7 13 5.9 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) Arrestin_C PF02752.17 KOS20809.1 - 4.2e-18 65.7 0.0 2.1e-17 63.4 0.0 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KOS20809.1 - 9.7e-09 35.2 0.0 0.0003 20.6 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain NUDIX PF00293.23 KOS20810.1 - 4e-15 55.6 1.2 6.1e-15 55.0 0.8 1.4 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 KOS20810.1 - 0.15 11.5 0.0 0.56 9.6 0.0 1.9 2 0 0 2 2 2 0 NUDIX domain CAP PF00188.21 KOS20812.1 - 1.7e-15 57.6 0.1 2.3e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Reo_sigmaC PF04582.7 KOS20813.1 - 2.2e-06 27.0 5.7 3e-06 26.6 4.0 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KOS20813.1 - 7.3e-06 25.8 5.5 0.00027 20.7 2.3 2.3 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 KOS20813.1 - 0.00047 20.3 5.9 0.099 12.9 0.9 3.1 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF869 PF05911.6 KOS20813.1 - 0.00049 18.4 1.0 0.00056 18.2 0.7 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Fez1 PF06818.10 KOS20813.1 - 0.00054 20.0 1.0 0.00054 20.0 0.7 1.9 1 1 1 2 2 2 1 Fez1 Syntaxin-6_N PF09177.6 KOS20813.1 - 0.00057 20.2 3.2 0.46 10.9 0.1 2.2 1 1 1 2 2 2 2 Syntaxin 6, N-terminal DELLA PF12041.3 KOS20813.1 - 0.00071 19.1 1.2 0.002 17.7 0.0 2.2 2 1 0 2 2 2 1 Transcriptional regulator DELLA protein N terminal AAA_13 PF13166.1 KOS20813.1 - 0.0015 17.0 2.5 0.0017 16.9 1.7 1.1 1 0 0 1 1 1 1 AAA domain THOC7 PF05615.8 KOS20813.1 - 0.0016 18.7 1.8 0.66 10.2 0.0 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 DUF1664 PF07889.7 KOS20813.1 - 0.0017 18.1 3.3 0.0027 17.4 1.8 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) TBPIP PF07106.8 KOS20813.1 - 0.0019 17.8 0.4 0.0041 16.6 0.1 1.6 1 1 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 KOS20813.1 - 0.0026 17.6 1.0 1.3 8.9 0.0 3.0 2 2 2 4 4 2 1 Flagella accessory protein C (FlaC) DUF1515 PF07439.6 KOS20813.1 - 0.0028 17.4 4.0 0.02 14.6 1.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1515) Myosin_tail_1 PF01576.14 KOS20813.1 - 0.0032 15.2 2.3 0.0041 14.9 1.6 1.1 1 0 0 1 1 1 1 Myosin tail IncA PF04156.9 KOS20813.1 - 0.0037 16.8 0.5 0.0071 15.9 0.3 1.5 1 1 0 1 1 1 1 IncA protein DUF3584 PF12128.3 KOS20813.1 - 0.0043 14.4 5.3 0.0052 14.2 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 KOS20813.1 - 0.0043 17.1 2.3 0.015 15.3 0.4 2.2 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family Spc7 PF08317.6 KOS20813.1 - 0.007 15.0 2.1 0.061 11.9 0.6 1.8 1 1 1 2 2 2 1 Spc7 kinetochore protein MscS_porin PF12795.2 KOS20813.1 - 0.0076 15.5 8.0 0.02 14.2 5.4 1.6 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain DUF2051 PF09738.4 KOS20813.1 - 0.008 15.5 3.5 0.013 14.8 1.4 1.7 1 1 1 2 2 2 1 Double stranded RNA binding protein (DUF2051) Prefoldin_2 PF01920.15 KOS20813.1 - 0.011 15.4 0.4 21 4.9 0.0 3.0 1 1 2 3 3 3 0 Prefoldin subunit DUF948 PF06103.6 KOS20813.1 - 0.013 15.3 1.6 0.16 11.8 0.3 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.8 KOS20813.1 - 0.016 14.3 1.0 0.031 13.3 0.6 1.4 1 1 1 2 2 2 0 TMPIT-like protein Laminin_II PF06009.7 KOS20813.1 - 0.016 14.9 8.2 0.027 14.2 0.8 2.2 1 1 1 2 2 2 0 Laminin Domain II Apolipoprotein PF01442.13 KOS20813.1 - 0.016 14.6 3.8 0.025 14.0 2.6 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain WEMBL PF05701.6 KOS20813.1 - 0.017 13.6 5.7 0.021 13.2 3.9 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light ATG16 PF08614.6 KOS20813.1 - 0.017 14.9 5.1 0.038 13.8 3.5 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2312 PF10073.4 KOS20813.1 - 0.019 14.3 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) HlyD PF00529.15 KOS20813.1 - 0.02 14.1 11.4 0.027 13.7 7.9 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DegQ PF08181.6 KOS20813.1 - 0.022 14.4 0.0 0.93 9.2 0.0 2.7 2 0 0 2 2 2 0 DegQ (SacQ) family Filament PF00038.16 KOS20813.1 - 0.033 13.6 5.3 0.12 11.7 3.5 1.9 1 1 0 1 1 1 0 Intermediate filament protein APG6 PF04111.7 KOS20813.1 - 0.038 13.0 2.0 0.097 11.7 1.0 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 FH2 PF02181.18 KOS20813.1 - 0.039 12.8 1.6 0.49 9.2 0.3 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF812 PF05667.6 KOS20813.1 - 0.048 12.1 5.4 0.066 11.7 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF211 PF02680.9 KOS20813.1 - 0.05 13.4 0.2 0.11 12.3 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 Syntaxin PF00804.20 KOS20813.1 - 0.052 13.7 3.5 0.93 9.6 0.7 2.2 1 1 1 2 2 2 0 Syntaxin CCDC144C PF14915.1 KOS20813.1 - 0.06 12.2 2.2 0.073 11.9 1.5 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region EzrA PF06160.7 KOS20813.1 - 0.06 11.5 3.7 0.13 10.4 2.5 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TPR_12 PF13424.1 KOS20813.1 - 0.067 13.1 2.2 3.9 7.4 1.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat CENP-F_leu_zip PF10473.4 KOS20813.1 - 0.067 13.0 0.6 0.36 10.6 0.5 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps53_N PF04100.7 KOS20813.1 - 0.074 11.8 2.4 0.074 11.8 1.3 1.3 1 1 0 1 1 1 0 Vps53-like, N-terminal GAS PF13851.1 KOS20813.1 - 0.079 12.1 0.7 0.18 10.9 0.5 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ArsR PF09824.4 KOS20813.1 - 0.08 12.2 0.4 0.15 11.3 0.2 1.5 1 1 0 1 1 1 0 ArsR transcriptional regulator Tropomyosin_1 PF12718.2 KOS20813.1 - 0.11 12.3 1.0 0.8 9.5 0.0 2.0 1 1 0 1 1 1 0 Tropomyosin like DUF4061 PF13270.1 KOS20813.1 - 0.13 12.3 2.7 0.26 11.4 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) MCPsignal PF00015.16 KOS20813.1 - 0.15 11.6 13.8 0.13 11.7 8.0 1.7 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DASH_Duo1 PF08651.5 KOS20813.1 - 0.15 11.6 1.6 3.5 7.2 0.1 2.9 1 1 1 3 3 3 0 DASH complex subunit Duo1 Snf7 PF03357.16 KOS20813.1 - 0.15 11.4 7.0 3.2 7.1 5.5 2.3 1 1 1 2 2 2 0 Snf7 ALIX_LYPXL_bnd PF13949.1 KOS20813.1 - 0.16 10.8 3.3 0.34 9.8 2.3 1.6 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV COG2 PF06148.6 KOS20813.1 - 0.17 11.7 4.5 0.57 10.0 0.7 2.7 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MT PF12777.2 KOS20813.1 - 0.18 10.5 3.6 0.12 11.0 0.4 1.8 1 1 1 2 2 2 0 Microtubule-binding stalk of dynein motor Tropomyosin PF00261.15 KOS20813.1 - 0.18 10.8 3.3 0.66 9.0 2.3 1.8 1 1 0 1 1 1 0 Tropomyosin Cortex-I_coil PF09304.5 KOS20813.1 - 0.2 11.7 4.0 1.6 8.8 0.5 2.5 1 1 2 3 3 3 0 Cortexillin I, coiled coil T2SF PF00482.18 KOS20813.1 - 0.21 11.4 3.1 0.28 11.1 1.9 1.4 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F IFT57 PF10498.4 KOS20813.1 - 0.24 10.0 2.1 0.39 9.4 1.1 1.5 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Orthopox_A5L PF06193.6 KOS20813.1 - 0.27 11.1 3.8 0.35 10.7 2.6 1.2 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like DUF4035 PF13227.1 KOS20813.1 - 0.29 10.5 2.0 0.46 9.8 0.5 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF4035) Cluap1 PF10234.4 KOS20813.1 - 0.29 10.2 3.2 1.5 7.9 2.2 1.9 1 1 0 1 1 1 0 Clusterin-associated protein-1 Snapin_Pallidin PF14712.1 KOS20813.1 - 0.3 11.4 3.8 1.3 9.3 0.6 2.4 1 1 1 2 2 2 0 Snapin/Pallidin DUF2968 PF11180.3 KOS20813.1 - 0.3 10.4 11.0 0.027 13.8 3.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF2664 PF10867.3 KOS20813.1 - 0.35 11.5 8.1 0.67 10.6 1.0 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF2664) Atg14 PF10186.4 KOS20813.1 - 0.39 9.5 2.7 0.6 8.9 1.8 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 KOS20813.1 - 0.4 10.7 3.7 1 9.4 0.4 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.3 KOS20813.1 - 0.49 10.2 3.7 1.4 8.8 2.5 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding ATP-synt_D PF01813.12 KOS20813.1 - 0.69 9.4 5.5 2.3 7.7 3.7 1.9 1 1 1 2 2 2 0 ATP synthase subunit D FliJ PF02050.11 KOS20813.1 - 0.8 9.7 7.9 0.94 9.5 1.4 2.2 1 1 2 3 3 3 0 Flagellar FliJ protein YlqD PF11068.3 KOS20813.1 - 0.83 9.7 4.9 24 4.9 3.7 2.2 1 1 1 2 2 2 0 YlqD protein BRE1 PF08647.6 KOS20813.1 - 1.2 9.1 6.4 0.77 9.7 0.3 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2937 PF11157.3 KOS20813.1 - 1.6 8.0 7.6 0.65 9.3 3.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) WXG100 PF06013.7 KOS20813.1 - 2.3 8.3 12.9 6.9 6.7 0.1 3.5 1 1 1 3 3 3 0 Proteins of 100 residues with WXG Nup54 PF13874.1 KOS20813.1 - 2.3 7.8 5.8 1.9 8.1 1.1 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF4164 PF13747.1 KOS20813.1 - 2.3 8.3 9.5 6.9 6.8 2.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) HrpB7 PF09486.5 KOS20813.1 - 3.1 7.6 13.4 6.7 6.6 9.3 1.7 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) HAUS6_N PF14661.1 KOS20813.1 - 4.5 6.5 7.0 4 6.7 1.8 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF605 PF04652.11 KOS20814.1 - 3.3 6.9 27.5 4.2 6.6 19.0 1.1 1 0 0 1 1 1 0 Vta1 like Sugar_tr PF00083.19 KOS20815.1 - 9.9e-29 100.1 32.1 5.3e-19 68.1 7.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KOS20815.1 - 4.2e-24 84.9 29.6 6.6e-17 61.2 9.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KOS20815.1 - 0.00059 18.3 7.9 0.00059 18.3 5.5 2.8 2 1 1 3 3 3 1 MFS/sugar transport protein Trep_Strep PF09605.5 KOS20815.1 - 0.85 9.2 13.3 1.4 8.5 5.8 3.2 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Fungal_trans PF04082.13 KOS20816.1 - 4.6e-22 78.1 0.1 8.2e-22 77.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS20816.1 - 4.5e-07 29.6 14.3 4.5e-07 29.6 9.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3_6 PF12913.2 KOS20816.1 - 0.14 11.4 0.1 0.5 9.6 0.0 1.9 2 0 0 2 2 2 0 SH3 domain of the SH3b1 type WD40 PF00400.27 KOS20817.1 - 3.4e-22 77.4 1.6 1.9e-05 24.3 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 KOS20817.1 - 3.2e-05 22.2 0.0 0.0047 15.1 0.0 2.4 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Cyclin_N PF00134.18 KOS20818.1 - 2.8e-43 146.5 0.3 5.5e-43 145.5 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KOS20818.1 - 5.1e-32 110.2 0.1 5.1e-32 110.2 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain Prp31_C PF09785.4 KOS20819.1 - 1.6e-42 144.8 0.6 1.6e-42 144.8 0.4 2.3 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 KOS20819.1 - 1.5e-39 134.6 0.4 2.9e-39 133.7 0.3 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KOS20819.1 - 4.6e-20 71.1 0.0 9.2e-20 70.2 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain zf-C2H2_4 PF13894.1 KOS20820.1 - 0.00016 21.7 9.6 0.0014 18.7 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KOS20820.1 - 0.001 19.2 12.8 0.0041 17.3 0.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KOS20820.1 - 0.0023 18.1 1.8 0.0023 18.1 1.3 3.0 3 0 0 3 3 3 1 Zinc-finger double domain Integrin_B_tail PF07965.7 KOS20820.1 - 0.015 15.6 1.1 0.028 14.8 0.3 1.7 1 1 1 2 2 2 0 Integrin beta tail domain zf-met PF12874.2 KOS20820.1 - 0.029 14.5 5.7 0.37 11.0 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Acetate_kinase PF00871.12 KOS20821.1 - 1.6e-72 244.2 0.0 4.4e-72 242.7 0.0 1.8 1 1 0 1 1 1 1 Acetokinase family TPR_14 PF13428.1 KOS20824.1 - 5.3e-19 66.9 32.5 0.00063 20.1 0.0 10.9 7 5 5 12 12 12 5 Tetratricopeptide repeat HAT PF02184.11 KOS20824.1 - 9.6e-19 66.8 13.4 2.8e-11 42.9 1.5 13.0 14 1 0 14 14 13 4 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 KOS20824.1 - 3.1e-16 59.4 3.5 8.5e-05 22.8 0.0 7.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 KOS20824.1 - 4.7e-15 55.8 28.7 0.044 14.4 0.9 8.2 8 1 0 9 9 8 6 Tetratricopeptide repeat Suf PF05843.9 KOS20824.1 - 1.4e-11 44.6 15.4 0.013 15.2 0.0 5.7 4 2 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_17 PF13431.1 KOS20824.1 - 1.5e-08 34.1 1.7 0.41 10.9 0.0 5.4 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_15 PF13429.1 KOS20824.1 - 6.1e-08 32.0 14.8 0.0046 16.0 0.9 5.1 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.1 KOS20824.1 - 1.2e-05 25.4 10.9 20 5.8 0.0 7.9 7 0 0 7 7 7 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 KOS20824.1 - 2.7e-05 23.8 17.3 0.081 12.6 0.4 6.8 4 2 1 6 6 6 1 U3 small nucleolar RNA-associated protein 6 TPR_11 PF13414.1 KOS20824.1 - 6.6e-05 22.4 5.7 14 5.4 0.0 6.0 5 1 1 6 6 6 0 TPR repeat TPR_8 PF13181.1 KOS20824.1 - 0.00015 21.3 0.0 7.9 6.5 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KOS20824.1 - 0.0057 16.5 22.5 0.3 11.0 0.0 7.3 7 2 1 8 8 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KOS20824.1 - 0.0069 16.2 5.4 7.4 6.5 0.3 5.0 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 KOS20824.1 - 0.0089 15.8 23.1 3.1 7.9 0.0 7.8 9 0 0 9 9 8 2 Tetratricopeptide repeat CENP-B_dimeris PF09026.5 KOS20824.1 - 0.094 12.9 8.4 0.25 11.5 5.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 KOS20824.1 - 0.39 8.6 7.6 0.65 7.9 5.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 KOS20824.1 - 0.97 8.9 9.3 1.7 8.1 6.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin c-SKI_SMAD_bind PF08782.5 KOS20824.1 - 2 8.6 4.4 8.7 6.5 0.0 3.9 4 0 0 4 4 3 0 c-SKI Smad4 binding domain DNA_pol_phi PF04931.8 KOS20824.1 - 2 6.0 8.3 3.4 5.3 5.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.6 KOS20824.1 - 4.7 7.0 10.4 2.3 7.9 4.8 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Glyco_hydro_18 PF00704.23 KOS20825.1 - 1.9e-73 247.8 0.0 2.2e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 KOS20825.1 - 0.00058 19.5 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) Rad9 PF04139.8 KOS20826.1 - 3.3e-64 216.4 0.3 4e-64 216.1 0.2 1.1 1 0 0 1 1 1 1 Rad9 FAR1 PF03101.10 KOS20827.1 - 4.9e-05 23.7 0.0 8.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 KOS20827.1 - 0.0047 17.1 0.0 0.007 16.5 0.0 1.4 1 0 0 1 1 1 1 Transcription factor AFT Sugarporin_N PF11471.3 KOS20827.1 - 0.0062 16.1 0.1 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension XhlA PF10779.4 KOS20827.1 - 0.021 14.7 0.0 0.042 13.7 0.0 1.5 1 1 0 1 1 1 0 Haemolysin XhlA Hemagglutinin PF00509.13 KOS20827.1 - 0.032 12.4 0.0 0.044 11.9 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin MtrG PF04210.8 KOS20827.1 - 0.089 12.4 0.2 0.21 11.3 0.1 1.7 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF605 PF04652.11 KOS20828.1 - 0.12 11.6 14.9 0.16 11.3 10.3 1.1 1 0 0 1 1 1 0 Vta1 like C1_3 PF07649.7 KOS20828.1 - 0.2 11.6 0.1 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 C1-like domain Mpv17_PMP22 PF04117.7 KOS20829.1 - 1.4e-11 43.8 1.5 6.9e-11 41.6 0.9 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family FANCI_S2 PF14676.1 KOS20829.1 - 0.082 12.8 0.1 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 FANCI solenoid 2 DUF1290 PF06947.7 KOS20829.1 - 0.19 11.6 1.9 0.68 9.8 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1290) RCC1 PF00415.13 KOS20830.1 - 2.9e-21 75.4 22.7 4.1e-11 42.9 0.0 7.2 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KOS20830.1 - 2.7e-19 68.2 26.0 2.4e-06 26.9 0.4 5.7 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat PDH PF02153.12 KOS20831.1 - 1.9e-13 49.9 0.0 2.6e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase HAD PF12710.2 KOS20832.1 - 2.3e-19 70.3 0.1 3.5e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS20832.1 - 4.4e-11 43.6 3.1 4.7e-10 40.2 0.3 2.8 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KOS20832.1 - 3.9e-08 33.1 1.1 1.9e-07 30.9 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KOS20832.1 - 3.9e-05 23.9 0.0 0.00011 22.4 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 KOS20832.1 - 0.00058 18.9 0.2 0.00085 18.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Put_Phosphatase PF06888.7 KOS20832.1 - 0.043 12.9 0.0 3.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Putative Phosphatase RRM_1 PF00076.17 KOS20834.1 - 7.1e-16 57.6 0.0 1e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS20834.1 - 6.1e-12 45.3 0.0 9.8e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS20834.1 - 1.8e-07 30.9 0.0 2.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.17 KOS20835.1 - 8.6e-59 199.2 0.0 1.2e-58 198.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PP_M1 PF03012.9 KOS20835.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoprotein Glyco_hydro_47 PF01532.15 KOS20836.1 - 5.4e-155 516.4 0.0 6.3e-155 516.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TP_methylase PF00590.15 KOS20837.1 - 4.1e-43 147.5 1.3 1.4e-42 145.7 0.9 1.9 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 KOS20837.1 - 1.7e-12 47.5 0.0 3.4e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KOS20837.1 - 1.4e-09 37.0 0.4 5.9e-06 25.4 0.1 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KOS20837.1 - 3.3e-06 25.9 0.1 3.3e-06 25.9 0.0 2.7 3 0 0 3 3 3 1 Sirohaem biosynthesis protein central NAD_binding_6 PF08030.7 KOS20838.1 - 4.7e-20 72.0 0.0 6.8e-18 65.0 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KOS20838.1 - 1.4e-19 70.3 9.0 1.4e-19 70.3 6.2 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KOS20838.1 - 1.8e-11 43.8 0.2 5.1e-10 39.1 0.0 2.9 2 1 0 2 2 2 1 FAD-binding domain DUF1690 PF07956.6 KOS20839.1 - 3.8e-28 98.2 0.2 4.5e-28 97.9 0.1 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF3708 PF12501.3 KOS20839.1 - 0.021 14.6 0.5 0.03 14.1 0.4 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF853 PF05872.7 KOS20839.1 - 0.042 12.1 0.4 0.05 11.9 0.3 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) LptE PF04390.7 KOS20839.1 - 0.07 12.8 1.2 0.12 12.1 0.4 1.4 1 1 1 2 2 2 0 Lipopolysaccharide-assembly Cep57_CLD_2 PF14197.1 KOS20839.1 - 3.1 7.8 11.7 0.7 9.8 3.2 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 TYW3 PF02676.9 KOS20840.1 - 1e-58 197.8 0.0 1.3e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 PAPS_reduct PF01507.14 KOS20841.1 - 2.4e-42 144.7 0.0 2.9e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family MR_MLE_C PF13378.1 KOS20842.1 - 1.6e-20 73.0 0.0 4.1e-20 71.8 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KOS20842.1 - 9.8e-12 45.2 0.0 2.6e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KOS20842.1 - 3.1e-09 36.8 0.0 5.1e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.10 KOS20842.1 - 0.1 11.7 0.0 0.32 10.0 0.0 1.7 2 0 0 2 2 2 0 Beta-galactosidase Serum_albumin PF00273.15 KOS20843.1 - 0.066 12.6 0.5 0.089 12.2 0.4 1.2 1 0 0 1 1 1 0 Serum albumin family LRR_4 PF12799.2 KOS20844.1 - 2.4e-12 46.1 7.3 1.4e-10 40.5 1.7 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS20844.1 - 1e-10 41.1 4.2 3.5e-10 39.4 2.9 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 KOS20844.1 - 5.8e-06 25.6 12.4 0.006 16.4 0.0 4.8 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KOS20844.1 - 2.4e-05 23.7 13.1 0.029 14.4 0.1 4.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 KOS20844.1 - 0.004 17.0 1.0 0.71 10.1 0.4 3.0 2 0 0 2 2 2 1 Leucine Rich repeat LRR_3 PF07725.7 KOS20844.1 - 2 8.3 5.9 5.3 6.9 0.1 2.7 2 0 0 2 2 2 0 Leucine Rich Repeat Pectate_lyase_3 PF12708.2 KOS20845.1 - 4.7e-51 174.0 2.9 1.1e-35 123.7 0.0 3.0 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KOS20845.1 - 3.3e-06 26.4 1.4 0.074 12.5 0.1 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase PTR2 PF00854.16 KOS20846.1 - 2.8e-36 125.1 14.0 2.8e-36 125.1 9.7 1.5 2 0 0 2 2 2 1 POT family CcmH PF03918.9 KOS20846.1 - 0.036 13.0 0.9 3.8 6.4 0.1 2.5 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Glutaredoxin PF00462.19 KOS20847.1 - 6.5e-19 67.6 0.0 2.8e-18 65.6 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 KOS20847.1 - 3e-15 55.7 0.0 5.8e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KOS20847.1 - 0.022 14.8 0.0 2.1 8.5 0.0 2.6 1 1 1 2 2 2 0 Thioredoxin-like GST_N_3 PF13417.1 KOS20847.1 - 0.14 12.3 0.0 0.88 9.8 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain SH3_9 PF14604.1 KOS20848.1 - 3.9e-29 99.9 4.0 2.9e-16 58.7 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KOS20848.1 - 1.4e-26 91.5 3.8 1.1e-13 50.2 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KOS20848.1 - 1.4e-14 53.3 0.5 2.9e-06 26.6 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 KOS20848.1 - 3.4e-11 43.1 0.0 6e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein F-box-like PF12937.2 KOS20849.1 - 4.8e-05 22.9 0.0 9.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS20849.1 - 0.0026 17.3 0.0 0.0062 16.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain Fungal_trans PF04082.13 KOS20850.1 - 3.9e-16 58.7 2.1 3.9e-16 58.7 1.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain eIF-3_zeta PF05091.7 KOS20851.1 - 2.7e-198 659.8 0.0 3.3e-198 659.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 KOS20851.1 - 0.0042 16.5 0.1 0.014 14.8 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF569) FMN_bind_2 PF04299.7 KOS20852.1 - 0.14 11.6 0.0 0.33 10.4 0.0 1.6 2 0 0 2 2 2 0 Putative FMN-binding domain WWbp PF10349.4 KOS20853.1 - 0.012 16.5 18.3 0.02 15.7 12.7 1.3 1 1 0 1 1 1 0 WW-domain ligand protein PAT1 PF09770.4 KOS20854.1 - 0.017 13.4 7.2 0.031 12.5 5.0 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SDA1 PF05285.7 KOS20854.1 - 0.022 14.0 8.6 0.034 13.4 6.0 1.2 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.6 KOS20854.1 - 0.044 13.5 12.5 0.48 10.2 3.6 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal PBP1_TM PF14812.1 KOS20854.1 - 0.049 13.9 21.2 0.32 11.3 1.4 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 KOS20854.1 - 0.28 10.7 15.7 1.8 8.1 0.3 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 KOS20854.1 - 0.98 9.6 18.9 0.87 9.8 5.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.7 KOS20854.1 - 2.3 7.8 15.2 2.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.1 KOS20854.1 - 2.5 7.7 9.3 3.5 7.2 0.2 2.3 2 0 0 2 2 2 0 FAM176 family DUF506 PF04720.7 KOS20854.1 - 3.4 7.2 5.5 5 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF506) LIM PF00412.17 KOS20855.1 - 5.6e-25 87.1 23.4 6e-09 35.8 2.3 3.4 3 0 0 3 3 3 3 LIM domain Nudix_N_2 PF14803.1 KOS20855.1 - 0.0029 17.2 8.5 2.4 7.9 0.6 5.0 4 0 0 4 4 4 2 Nudix N-terminal zf-ribbon_3 PF13248.1 KOS20855.1 - 0.13 11.5 13.8 1.5 8.1 2.4 4.3 3 1 0 3 3 3 0 zinc-ribbon domain Auto_anti-p27 PF06677.7 KOS20855.1 - 0.22 11.3 7.7 5.3 6.8 0.1 3.9 3 1 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CN_hydrolase PF00795.17 KOS20856.1 - 2.3e-26 92.3 0.2 3.7e-26 91.6 0.1 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NatB_MDM20 PF09797.4 KOS20857.1 - 5.8e-39 133.8 0.0 1.1e-38 132.8 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Myb_DNA-binding PF00249.26 KOS20857.1 - 0.036 14.1 0.5 29 4.8 0.0 3.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain Prenyltrans PF00432.16 KOS20858.1 - 2e-34 116.8 6.5 4.4e-09 35.7 0.0 5.7 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KOS20858.1 - 1.8e-22 79.9 0.3 3e-15 56.5 0.0 4.1 1 1 3 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KOS20858.1 - 1.1e-08 34.9 0.1 0.0002 21.3 0.0 4.2 2 1 2 4 4 4 3 Prenyltransferase-like DUF1903 PF08991.5 KOS20858.1 - 0.0037 17.3 3.0 0.0037 17.3 2.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KOS20858.1 - 0.56 10.1 4.5 1.2 9.1 3.1 1.6 1 0 0 1 1 1 0 CHCH domain Ilm1 PF10311.4 KOS20859.1 - 1.2e-50 171.2 0.6 1.4e-50 171.0 0.4 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Pkinase PF00069.20 KOS20860.1 - 6.3e-66 222.1 0.0 9.4e-66 221.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS20860.1 - 8e-38 129.9 0.0 1.2e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS20860.1 - 2.8e-09 36.3 0.0 8.4e-08 31.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KOS20860.1 - 0.011 15.4 1.3 0.052 13.2 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 KOS20860.1 - 0.035 13.1 0.0 0.096 11.7 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KOS20860.1 - 0.16 10.7 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 IFT43 PF15305.1 KOS20860.1 - 0.28 11.2 7.4 0.21 11.6 1.3 2.6 2 0 0 2 2 2 0 Intraflagellar transport protein 43 SNF2_N PF00176.18 KOS20861.1 - 1.4e-43 148.8 0.3 2.2e-22 79.2 0.0 2.5 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS20861.1 - 3.9e-15 55.4 0.1 1.4e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KOS20861.1 - 0.00019 20.3 0.1 0.14 10.9 0.0 2.5 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 UQ_con PF00179.21 KOS20862.1 - 4.3e-47 159.0 0.0 4.9e-47 158.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS20862.1 - 0.00036 20.2 0.0 0.00046 19.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KOS20862.1 - 0.0011 18.6 0.1 0.0021 17.7 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 KOS20862.1 - 0.016 15.1 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain Mt_ATP-synt_D PF05873.7 KOS20863.1 - 7.2e-17 61.4 1.7 9.3e-17 61.1 1.2 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Dor1 PF04124.7 KOS20863.1 - 0.035 12.5 2.6 0.044 12.2 1.8 1.2 1 0 0 1 1 1 0 Dor1-like family Cob_adeno_trans PF01923.13 KOS20863.1 - 0.063 13.0 0.2 0.15 11.8 0.1 1.5 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Laminin_II PF06009.7 KOS20863.1 - 0.47 10.2 5.2 2.6 7.8 0.1 2.6 1 1 1 2 2 2 0 Laminin Domain II HrpB7 PF09486.5 KOS20863.1 - 0.72 9.7 8.2 0.92 9.4 1.2 2.5 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Spectrin PF00435.16 KOS20863.1 - 1.1 9.5 5.8 2.4 8.5 0.2 2.3 1 1 2 3 3 3 0 Spectrin repeat Tropomyosin_1 PF12718.2 KOS20863.1 - 5.3 6.8 9.7 12 5.7 0.2 2.7 1 1 2 3 3 3 0 Tropomyosin like NAC PF01849.13 KOS20864.1 - 1.5e-24 85.3 0.2 1.5e-23 82.0 0.0 2.3 2 0 0 2 2 2 1 NAC domain Packaging_FI PF14000.1 KOS20864.1 - 0.012 15.8 0.4 0.012 15.8 0.2 2.3 2 1 0 2 2 2 0 DNA packaging protein FI Phage_prot_Gp6 PF05133.9 KOS20864.1 - 0.015 13.8 3.7 0.065 11.7 3.0 1.6 1 1 1 2 2 2 0 Phage portal protein, SPP1 Gp6-like PEX11 PF05648.9 KOS20864.1 - 0.14 11.4 2.3 0.086 12.1 0.4 1.5 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) UBA PF00627.26 KOS20864.1 - 0.55 10.1 3.1 0.29 11.0 0.3 2.0 2 0 0 2 2 2 0 UBA/TS-N domain Ribosomal_S13 PF00416.17 KOS20864.1 - 0.64 10.4 3.4 0.79 10.2 0.3 2.4 3 0 0 3 3 3 0 Ribosomal protein S13/S18 SPX PF03105.14 KOS20864.1 - 0.79 9.4 6.6 0.45 10.2 1.7 1.9 2 0 0 2 2 2 0 SPX domain CENP-B_dimeris PF09026.5 KOS20864.1 - 0.97 9.7 13.9 4.4 7.6 6.6 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pox_RNA_Pol_19 PF05320.7 KOS20864.1 - 1.9 8.1 12.4 6.4 6.4 5.3 2.3 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit FAM176 PF14851.1 KOS20864.1 - 2.7 7.6 14.2 2.3 7.8 4.4 2.2 2 0 0 2 2 2 0 FAM176 family Cytomega_UL84 PF06284.6 KOS20864.1 - 8.2 4.7 9.6 6 5.1 6.1 1.2 1 1 0 1 1 1 0 Cytomegalovirus UL84 protein Ribosomal_L14e PF01929.12 KOS20865.1 - 3.5e-22 78.5 3.3 4.8e-22 78.1 2.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 KOS20865.1 - 0.0083 15.8 0.3 0.025 14.2 0.0 1.9 2 0 0 2 2 2 1 KOW motif DUF1687 PF07955.6 KOS20866.1 - 7.9e-16 58.2 0.1 1.3e-15 57.5 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) L51_S25_CI-B8 PF05047.11 KOS20868.1 - 2e-13 49.8 0.0 2.6e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.8 KOS20869.1 - 1.3e-40 138.0 1.5 1.8e-40 137.6 1.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 KOS20869.1 - 0.037 13.8 0.3 0.054 13.3 0.2 1.2 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange CNH PF00780.17 KOS20870.1 - 6.2e-60 202.9 0.0 1.2e-59 202.0 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KOS20870.1 - 3.9e-33 114.8 0.4 7.1e-33 113.9 0.3 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KOS20870.1 - 2.7e-07 30.5 0.2 2.1e-05 24.4 0.1 3.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KOS20870.1 - 0.0018 18.4 0.0 0.0065 16.6 0.0 2.0 1 1 0 1 1 1 1 PH domain Sod_Cu PF00080.15 KOS20871.1 - 1.2e-44 151.9 3.7 1.3e-44 151.7 2.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Hexapep PF00132.19 KOS20871.1 - 0.099 12.1 0.8 0.36 10.4 0.5 2.0 1 1 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) NDUF_B8 PF05821.6 KOS20872.1 - 1.1e-08 34.8 0.3 1.5e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) G-patch PF01585.18 KOS20873.1 - 1.3e-09 37.6 2.2 2.6e-09 36.6 1.5 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KOS20873.1 - 5.6e-06 26.1 3.5 6.3e-06 25.9 0.2 2.4 2 0 0 2 2 2 1 DExH-box splicing factor binding site zf-RanBP PF00641.13 KOS20873.1 - 0.00085 18.3 3.5 0.00085 18.3 2.4 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others RED_N PF07808.8 KOS20873.1 - 0.0043 16.2 3.0 0.0099 15.1 2.1 1.6 1 0 0 1 1 1 1 RED-like protein N-terminal region zf-C2H2_2 PF12756.2 KOS20873.1 - 0.022 14.8 1.2 0.05 13.7 0.1 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RRM_1 PF00076.17 KOS20873.1 - 0.03 13.9 0.0 0.45 10.1 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 KOS20873.1 - 0.81 9.9 4.5 0.66 10.1 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FAM220 PF15487.1 KOS20873.1 - 5.2 6.3 12.6 0.086 12.1 2.1 2.2 2 0 0 2 2 2 0 FAM220 family Rtf2 PF04641.7 KOS20873.1 - 6.7 5.8 14.4 0.18 10.9 3.1 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger 4HBT_3 PF13622.1 KOS20874.1 - 4.4e-45 154.4 7.7 7.7e-45 153.6 5.4 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KOS20874.1 - 1.9e-23 82.5 0.0 7.6e-11 41.7 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase DUF3682 PF12446.3 KOS20874.1 - 2.3 8.4 13.7 0.57 10.4 6.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) ALO PF04030.9 KOS20875.1 - 9.3e-88 294.1 0.0 1.3e-87 293.6 0.0 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KOS20875.1 - 3.5e-27 94.5 0.0 5.3e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF2215 PF10225.4 KOS20876.1 - 0.29 10.5 1.2 0.65 9.3 0.8 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF2229 PF09989.4 KOS20876.1 - 9.5 5.6 7.2 0.33 10.3 0.3 2.0 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) adh_short PF00106.20 KOS20878.1 - 1.3e-28 100.0 1.0 2e-28 99.3 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS20878.1 - 6.3e-16 58.8 0.0 7.6e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS20878.1 - 1.5e-13 50.8 0.6 2.5e-13 50.1 0.4 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KOS20878.1 - 0.0064 16.5 0.2 0.009 16.0 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding CBFD_NFYB_HMF PF00808.18 KOS20879.1 - 3e-18 65.6 0.2 5.6e-18 64.7 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KOS20879.1 - 0.00067 19.7 0.2 0.003 17.6 0.0 2.0 1 1 2 3 3 3 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KOS20879.1 - 0.015 14.9 0.0 0.068 12.9 0.0 1.9 1 1 1 2 2 2 0 Bromodomain associated S-methyl_trans PF02574.11 KOS20880.1 - 6.1e-19 68.4 0.0 9.5e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Homocysteine S-methyltransferase DAO PF01266.19 KOS20881.1 - 2.4e-38 131.9 11.9 4.2e-38 131.1 8.3 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KOS20881.1 - 0.0012 18.8 0.0 0.0044 17.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KOS20881.1 - 0.0014 18.9 0.0 0.67 10.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KOS20881.1 - 0.0031 17.4 0.0 0.5 10.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS20881.1 - 0.21 11.3 1.5 0.62 9.8 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Romo1 PF10247.4 KOS20882.1 - 1.3e-26 92.5 14.6 1.6e-26 92.2 10.1 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 KOS20882.1 - 0.033 14.2 4.1 0.044 13.8 2.8 1.3 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family VirB3 PF05101.8 KOS20882.1 - 0.15 12.0 0.6 0.24 11.4 0.0 1.6 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Phage_holin_5 PF06946.6 KOS20882.1 - 0.32 11.1 2.5 0.44 10.7 1.8 1.2 1 0 0 1 1 1 0 Phage holin FHA PF00498.21 KOS20883.1 - 1.7e-16 60.0 0.1 5e-16 58.5 0.1 1.9 1 0 0 1 1 1 1 FHA domain SIR2 PF02146.12 KOS20884.1 - 2.6e-53 180.4 0.0 4.4e-53 179.6 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 KOS20884.1 - 0.032 13.9 0.5 0.5 10.1 0.0 2.8 2 1 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain Cu-oxidase_3 PF07732.10 KOS20885.1 - 1.5e-44 150.5 1.7 7e-42 141.8 0.0 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 KOS20885.1 - 1.2e-36 125.9 0.0 1.8e-35 122.1 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KOS20885.1 - 3.3e-33 114.1 11.7 2.5e-32 111.2 2.1 3.9 3 1 0 3 3 3 2 Multicopper oxidase ATP13 PF12921.2 KOS20886.1 - 5.1e-12 45.2 0.0 1.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ATPase expression LSM PF01423.17 KOS20887.1 - 1.4e-12 46.9 0.2 1.7e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain COX16 PF14138.1 KOS20888.1 - 1.8e-30 104.9 0.1 2.2e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 MCM2_N PF12619.3 KOS20889.1 - 0.042 13.8 0.9 0.065 13.2 0.6 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Oxidored_FMN PF00724.15 KOS20890.1 - 1.1e-75 254.7 0.0 1.3e-75 254.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Thioredoxin PF00085.15 KOS20891.1 - 1e-64 214.7 4.8 3.9e-31 106.8 0.1 4.8 5 0 0 5 5 5 3 Thioredoxin Thioredoxin_6 PF13848.1 KOS20891.1 - 6.2e-47 159.7 5.9 3e-36 124.9 1.0 3.7 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KOS20891.1 - 3.2e-12 46.3 0.3 0.0051 16.9 0.0 5.2 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KOS20891.1 - 1.3e-09 38.2 6.4 0.0037 17.4 0.1 5.5 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KOS20891.1 - 1.3e-09 37.9 0.0 0.001 19.0 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.12 KOS20891.1 - 1.4e-06 27.3 3.0 1.4e-06 27.3 2.1 1.5 2 0 0 2 2 2 1 Calsequestrin Redoxin PF08534.5 KOS20891.1 - 5.9e-06 25.8 2.2 0.068 12.7 0.0 3.6 3 0 0 3 3 3 2 Redoxin AhpC-TSA PF00578.16 KOS20891.1 - 0.00012 21.7 1.7 0.27 10.9 0.1 3.3 2 1 1 3 3 3 2 AhpC/TSA family Thioredoxin_3 PF13192.1 KOS20891.1 - 0.0092 15.7 0.1 0.055 13.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain Ribosomal_60s PF00428.14 KOS20891.1 - 0.11 12.9 16.1 0.4 11.1 10.3 2.7 2 0 0 2 2 1 0 60s Acidic ribosomal protein Thioredoxin_4 PF13462.1 KOS20891.1 - 0.15 12.0 7.3 2.3 8.2 0.1 3.6 3 2 0 3 3 3 0 Thioredoxin PSP1 PF04468.7 KOS20891.1 - 0.5 10.3 0.0 0.5 10.3 0.0 2.8 3 0 0 3 3 2 0 PSP1 C-terminal conserved region U1snRNP70_N PF12220.3 KOS20891.1 - 1.2 9.5 10.2 0.24 11.7 3.9 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal LPP PF04728.8 KOS20892.1 - 0.0018 17.9 0.1 0.0027 17.4 0.1 1.2 1 0 0 1 1 1 1 Lipoprotein leucine-zipper zf-HIT PF04438.11 KOS20893.1 - 2.2e-09 36.8 5.2 3.1e-09 36.3 3.6 1.2 1 0 0 1 1 1 1 HIT zinc finger Gly-zipper_OmpA PF13436.1 KOS20893.1 - 0.28 10.8 25.0 0.045 13.4 14.3 1.8 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain tRNA-synt_2b PF00587.20 KOS20894.1 - 3.4e-43 147.1 0.1 7.4e-43 146.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KOS20894.1 - 5e-18 64.8 0.2 9.9e-18 63.8 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 KOS20894.1 - 5.9e-13 48.4 0.0 1.3e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 KOS20894.1 - 8.3e-11 41.5 0.0 2.6e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 TGS domain Exonuc_V_gamma PF04257.9 KOS20894.1 - 0.11 10.4 0.2 0.29 9.0 0.0 1.7 3 0 0 3 3 3 0 Exodeoxyribonuclease V, gamma subunit WD40 PF00400.27 KOS20895.1 - 9.4e-10 37.9 0.5 2e-07 30.6 0.3 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF2415 PF10313.4 KOS20895.1 - 0.081 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Glyco_hydro_35 PF01301.14 KOS20896.1 - 2e-74 250.8 0.0 2.8e-74 250.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 KOS20896.1 - 7.7e-41 138.8 0.6 8.7e-21 74.2 0.1 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 KOS20896.1 - 3e-35 121.2 0.0 6e-35 120.2 0.0 1.5 1 1 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 KOS20896.1 - 3.9e-22 77.4 0.0 9.9e-22 76.1 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 DLH PF01738.13 KOS20897.1 - 2.9e-08 33.2 0.0 1.8e-07 30.6 0.0 1.8 1 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 KOS20897.1 - 0.0026 17.6 0.8 0.0048 16.8 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Acetyltransf_9 PF13527.1 KOS20898.1 - 6.2e-06 26.0 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KOS20898.1 - 1.7e-05 24.9 0.0 3.8e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS20898.1 - 2.6e-05 24.1 0.1 0.00038 20.4 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KOS20898.1 - 0.00056 19.6 0.0 0.05 13.3 0.0 2.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_13 PF13880.1 KOS20898.1 - 0.028 14.1 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_10 PF13673.1 KOS20898.1 - 0.085 12.9 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FAR1 PF03101.10 KOS20900.1 - 0.0027 18.1 0.5 0.0027 18.1 0.4 2.2 2 0 0 2 2 2 1 FAR1 DNA-binding domain Peptidase_A21 PF03566.8 KOS20900.1 - 0.014 13.5 4.4 0.02 13.0 3.0 1.2 1 0 0 1 1 1 0 Peptidase family A21 MutS_V PF00488.16 KOS20901.1 - 6.1e-51 173.1 0.1 7.4e-51 172.8 0.1 1.1 1 0 0 1 1 1 1 MutS domain V WBS_methylT PF12589.3 KOS20902.1 - 4.6e-17 62.2 4.8 8.9e-17 61.3 3.3 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KOS20902.1 - 8.9e-12 45.3 0.0 1.6e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS20902.1 - 4.3e-07 30.2 0.0 8.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS20902.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS20902.1 - 6e-05 22.8 0.0 9.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS20902.1 - 6.3e-05 23.5 0.0 0.00017 22.1 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS20902.1 - 6.7e-05 23.2 0.0 0.00021 21.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KOS20902.1 - 0.00031 20.3 0.0 0.00061 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KOS20902.1 - 0.00045 20.2 0.1 0.001 19.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KOS20902.1 - 0.0092 15.0 0.0 0.076 12.0 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 KOS20902.1 - 0.031 13.4 0.0 0.067 12.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KOS20902.1 - 0.088 12.4 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain tRNA-synt_2 PF00152.15 KOS20903.1 - 1.7e-87 293.3 0.1 2.3e-87 292.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KOS20903.1 - 1.7e-07 31.0 0.0 5.7e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KOS20903.1 - 6.1e-07 28.8 0.2 0.0011 18.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) PBP PF01161.15 KOS20904.1 - 6.8e-16 58.4 0.0 8.5e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FeoA PF04023.9 KOS20904.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 FeoA domain Aminotran_4 PF01063.14 KOS20905.1 - 3.2e-22 79.1 0.0 4.2e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV IF-2B PF01008.12 KOS20906.1 - 2.3e-73 246.6 0.1 2.7e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF2205 PF10224.4 KOS20907.1 - 7.2e-30 102.3 0.7 9.6e-30 101.9 0.5 1.2 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) AAA_32 PF13654.1 KOS20907.1 - 0.012 14.3 0.1 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain TACC PF05010.9 KOS20907.1 - 0.053 13.2 0.1 0.069 12.9 0.1 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) p450 PF00067.17 KOS20908.1 - 1.5e-49 168.7 0.0 5.8e-48 163.5 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 DHHA2 PF02833.9 KOS20909.1 - 4.9e-23 81.6 0.0 7e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KOS20909.1 - 4.5e-10 39.3 0.1 1e-09 38.1 0.0 1.5 1 1 0 1 1 1 1 DHH family Oligomerisation PF02410.10 KOS20910.1 - 2.3e-05 24.3 0.0 0.00046 20.1 0.0 2.5 1 1 0 1 1 1 1 Oligomerisation domain RNA_pol PF00940.14 KOS20911.1 - 3.4e-160 532.9 0.0 9e-160 531.5 0.0 1.7 2 1 0 2 2 2 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KOS20911.1 - 2.7e-70 237.1 1.5 4.3e-70 236.4 1.0 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal tRNA_bind PF01588.15 KOS20912.1 - 3.4e-22 78.1 0.3 2.7e-21 75.2 0.2 2.2 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 KOS20912.1 - 3.9e-07 30.4 0.0 8.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KOS20912.1 - 7e-05 22.6 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KOS20912.1 - 0.00079 19.3 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DAP_epimerase PF01678.14 KOS20912.1 - 0.063 13.1 0.2 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Diaminopimelate epimerase NUC153 PF08159.7 KOS20913.1 - 3.3e-12 45.7 1.0 3.3e-12 45.7 0.7 3.6 5 0 0 5 5 5 2 NUC153 domain DEAD PF00270.24 KOS20914.1 - 9.3e-44 148.8 0.0 1.7e-43 148.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KOS20914.1 - 6.2e-25 86.5 0.0 1.2e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KOS20914.1 - 9.1e-22 76.7 0.0 2.2e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS20914.1 - 0.013 15.3 0.0 0.058 13.2 0.0 2.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sad1_UNC PF07738.8 KOS20915.1 - 1.4e-09 37.8 0.1 0.00043 20.0 0.1 2.3 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal tRNA_synt_1c_R1 PF04558.10 KOS20915.1 - 3.9e-05 23.2 0.1 8.3e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Epimerase PF01370.16 KOS20916.1 - 1e-43 149.4 0.0 1.4e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KOS20916.1 - 4.6e-24 84.1 0.1 1.1e-23 82.8 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KOS20916.1 - 3.1e-15 55.6 0.0 5.7e-15 54.7 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KOS20916.1 - 1.1e-13 50.7 0.0 3.9e-12 45.6 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KOS20916.1 - 6e-13 48.3 0.0 9.7e-13 47.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KOS20916.1 - 1.1e-11 44.9 0.1 1.6e-11 44.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KOS20916.1 - 2.5e-08 34.1 0.0 4.6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KOS20916.1 - 6e-08 31.9 0.0 2.2e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 KOS20916.1 - 7.7e-08 32.2 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_18 PF12847.2 KOS20916.1 - 0.00066 20.2 0.1 0.96 10.0 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Saccharop_dh PF03435.13 KOS20916.1 - 0.0024 16.9 0.0 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 KOS20916.1 - 0.012 14.8 0.0 0.057 12.6 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.9 KOS20916.1 - 0.025 13.9 0.1 0.045 13.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 KOS20916.1 - 0.039 12.8 0.1 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase SNF2_N PF00176.18 KOS20917.1 - 2.3e-71 240.0 0.7 3.3e-71 239.5 0.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS20917.1 - 1.1e-14 54.0 0.1 4e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS20917.1 - 1.7e-07 31.2 2.4 4.9e-07 29.7 0.0 2.8 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KOS20917.1 - 0.0003 20.3 0.0 0.00066 19.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KOS20917.1 - 0.02 15.0 0.2 0.09 12.9 0.0 2.2 2 1 1 3 3 3 0 AAA domain SBDS PF01172.13 KOS20919.1 - 2.1e-23 81.9 0.0 2.4e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein EF-1_beta_acid PF10587.4 KOS20919.1 - 0.081 13.0 0.2 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region E1-E2_ATPase PF00122.15 KOS20920.1 - 6.4e-63 211.8 5.4 3.5e-62 209.4 3.4 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KOS20920.1 - 6.3e-45 152.9 6.1 6.3e-45 152.9 4.3 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KOS20920.1 - 4.5e-31 108.9 0.0 2.1e-30 106.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS20920.1 - 5.9e-21 74.2 0.0 1.2e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KOS20920.1 - 2.3e-19 68.6 0.0 6.2e-19 67.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KOS20920.1 - 1.3e-15 58.0 0.0 6.5e-15 55.8 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KOS20920.1 - 5.2e-07 29.5 1.8 5e-06 26.2 0.8 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KOS20920.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase OPA3 PF07047.7 KOS20921.1 - 1.1e-39 135.2 1.4 1.5e-39 134.8 1.0 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Vpu PF00558.14 KOS20921.1 - 0.054 13.0 0.5 0.12 11.9 0.3 1.6 1 0 0 1 1 1 0 Vpu protein DUF3373 PF11853.3 KOS20921.1 - 0.067 11.7 0.1 0.091 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) FlgM PF04316.8 KOS20921.1 - 0.095 12.6 0.8 0.19 11.6 0.5 1.7 1 1 0 1 1 1 0 Anti-sigma-28 factor, FlgM IncA PF04156.9 KOS20921.1 - 0.31 10.6 4.4 0.64 9.5 3.1 1.4 1 0 0 1 1 1 0 IncA protein Osmo_CC PF08946.5 KOS20921.1 - 0.59 10.2 7.6 0.52 10.3 2.4 2.4 1 1 1 2 2 2 0 Osmosensory transporter coiled coil DUF4140 PF13600.1 KOS20921.1 - 2 8.8 6.6 0.33 11.4 0.5 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4184 PF13803.1 KOS20922.1 - 0.074 12.3 3.0 3.6 6.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4184) Chitin_synth_2 PF03142.10 KOS20923.1 - 4.6e-290 962.4 0.0 6.3e-290 962.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KOS20923.1 - 3.9e-18 65.8 1.6 1.3e-17 64.1 1.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KOS20923.1 - 3.4e-14 53.2 0.0 1.1e-11 44.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KOS20923.1 - 9.2e-11 41.4 0.0 1.9e-09 37.2 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 KOS20923.1 - 2e-05 23.9 0.0 0.00031 20.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KOS20923.1 - 0.0016 18.1 0.0 0.078 12.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Pkinase PF00069.20 KOS20924.1 - 2.1e-68 230.2 0.0 3.1e-68 229.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS20924.1 - 9.5e-41 139.5 0.0 1.5e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS20924.1 - 2.5e-08 33.2 0.0 6.3e-08 31.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like POLO_box PF00659.13 KOS20924.1 - 2.9e-08 33.5 0.0 2.7e-05 24.0 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 KOS20924.1 - 0.0028 16.7 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family VPR PF00522.13 KOS20924.1 - 0.5 10.2 2.4 1.8 8.4 0.3 2.9 3 1 0 3 3 3 0 VPR/VPX protein Myb_DNA-bind_6 PF13921.1 KOS20925.1 - 0.00018 21.5 0.1 0.00035 20.5 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain RXT2_N PF08595.6 KOS20925.1 - 0.017 14.9 0.5 0.017 14.9 0.3 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 KOS20925.1 - 0.064 12.8 6.2 1.5 8.3 1.4 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region HTH_23 PF13384.1 KOS20925.1 - 0.088 12.4 0.3 0.24 11.1 0.2 1.8 1 0 0 1 1 1 0 Homeodomain-like domain BAF1_ABF1 PF04684.8 KOS20925.1 - 0.15 10.9 0.1 0.15 10.9 0.1 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF3245 PF11595.3 KOS20925.1 - 0.51 10.5 11.0 0.51 10.6 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Nucleoplasmin PF03066.10 KOS20925.1 - 0.61 9.5 2.8 0.5 9.8 0.1 1.9 2 0 0 2 2 2 0 Nucleoplasmin DUF4611 PF15387.1 KOS20925.1 - 3 8.0 7.7 0.32 11.1 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 KOS20925.1 - 3.3 8.1 16.1 0.32 11.3 4.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sel1 PF08238.7 KOS20926.1 - 3.3e-37 126.0 26.0 2e-05 25.0 0.2 7.7 6 1 1 7 7 7 7 Sel1 repeat VMA21 PF09446.5 KOS20927.1 - 4.1e-13 49.0 7.2 5.9e-13 48.5 5.0 1.2 1 0 0 1 1 1 1 VMA21-like domain GRP PF07172.6 KOS20927.1 - 0.18 12.3 0.7 0.25 11.8 0.0 1.6 2 0 0 2 2 2 0 Glycine rich protein family Syndecan PF01034.15 KOS20927.1 - 0.26 10.9 2.3 0.54 9.9 1.6 1.7 1 1 0 1 1 1 0 Syndecan domain SNF2_N PF00176.18 KOS20928.1 - 3e-56 190.4 0.0 4.1e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS20928.1 - 1.9e-12 46.8 0.0 3.8e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Nucleoplasmin PF03066.10 KOS20928.1 - 0.0084 15.6 3.2 0.029 13.8 2.2 1.9 1 0 0 1 1 1 1 Nucleoplasmin Sigma70_ner PF04546.8 KOS20928.1 - 4.9 6.7 11.1 0.037 13.6 1.3 2.1 3 0 0 3 3 3 0 Sigma-70, non-essential region DUF566 PF04484.7 KOS20929.1 - 3.5 7.0 8.0 4 6.8 5.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) ILVD_EDD PF00920.16 KOS20930.1 - 2.3e-197 656.5 0.2 2.7e-197 656.3 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family PX PF00787.19 KOS20931.1 - 3.9e-19 68.5 0.1 8.3e-19 67.4 0.1 1.5 1 0 0 1 1 1 1 PX domain Trypan_PARP PF05887.6 KOS20931.1 - 0.022 14.5 3.7 0.042 13.6 2.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PAT1 PF09770.4 KOS20931.1 - 7.1 4.7 38.3 11 4.1 26.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.11 KOS20932.1 - 1.5e-131 438.2 0.1 1.9e-131 437.9 0.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4604 PF15377.1 KOS20933.1 - 1.2e-20 74.3 19.0 3.9e-20 72.6 13.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) REV PF00424.13 KOS20933.1 - 0.057 13.3 1.2 7.5 6.5 0.1 2.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Ribosomal_L18e PF00828.14 KOS20934.1 - 1.7e-21 76.9 0.9 3.5e-21 75.9 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 ADH_zinc_N_2 PF13602.1 KOS20935.1 - 1.6e-13 51.6 0.0 3.2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KOS20935.1 - 5.3e-09 35.7 0.0 9.9e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KOS20935.1 - 2.1e-05 24.2 0.0 4.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KOS20935.1 - 0.0005 20.1 1.4 0.00086 19.3 1.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KOS20935.1 - 0.011 15.6 1.0 0.028 14.3 0.2 1.9 2 0 0 2 2 2 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 KOS20935.1 - 0.028 14.7 0.0 0.071 13.4 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KOS20935.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 KOS20935.1 - 0.064 12.4 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 KOS20935.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4449 PF14613.1 KOS20936.1 - 0.015 15.2 0.3 0.045 13.6 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4449) COX5B PF01215.14 KOS20938.1 - 1.8e-39 134.5 0.0 2.7e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb 4HBT_3 PF13622.1 KOS20939.1 - 4.6e-33 115.0 6.0 5.6e-33 114.7 4.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DEAD PF00270.24 KOS20941.1 - 7.5e-38 129.6 0.0 1.7e-37 128.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS20941.1 - 8.2e-23 80.0 0.0 1.3e-13 50.6 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KOS20941.1 - 6.9e-05 22.7 0.9 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.9 KOS20941.1 - 0.00029 19.0 0.3 0.00047 18.3 0.2 1.4 1 0 0 1 1 1 1 CDC45-like protein CENP-B_dimeris PF09026.5 KOS20941.1 - 0.56 10.4 9.0 1.7 8.9 6.3 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HSP90 PF00183.13 KOS20941.1 - 2 6.6 12.0 3.5 5.9 8.3 1.3 1 0 0 1 1 1 0 Hsp90 protein Glyco_hydro_3 PF00933.16 KOS20943.1 - 2.2e-70 237.0 0.0 3e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KOS20943.1 - 9e-47 159.4 0.0 1.3e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KOS20943.1 - 1e-07 31.7 0.0 3.9e-07 29.9 0.0 2.0 1 1 1 2 2 2 1 Fibronectin type III-like domain Peptidase_M1 PF01433.15 KOS20944.1 - 1.9e-133 445.3 0.0 3e-133 444.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KOS20944.1 - 4.1e-87 292.4 0.2 8e-87 291.5 0.1 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KOS20944.1 - 5.7e-20 71.6 0.7 1.1e-19 70.7 0.5 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Sugar_tr PF00083.19 KOS20945.1 - 6.9e-122 407.2 26.0 7.9e-122 407.0 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS20945.1 - 1.2e-23 83.3 39.3 5.1e-18 64.9 12.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Isochorismatase PF00857.15 KOS20946.1 - 8.4e-15 55.1 0.0 1.2e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family TrbH PF07283.6 KOS20946.1 - 0.054 13.3 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Conjugal transfer protein TrbH Fungal_trans PF04082.13 KOS20947.1 - 1.6e-15 56.7 4.6 5.9e-15 54.8 0.2 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Pec_lyase_C PF00544.14 KOS20948.1 - 2e-19 69.8 4.6 5e-19 68.5 3.2 1.6 1 1 0 1 1 1 1 Pectate lyase Glyco_hydro_65m PF03632.10 KOS20950.1 - 8e-84 281.4 0.1 4.9e-83 278.8 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 KOS20950.1 - 1.5e-42 145.6 0.0 2.6e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 KOS20950.1 - 2.2e-05 24.4 0.0 4.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Methyltransf_16 PF10294.4 KOS20951.1 - 4.1e-15 55.6 0.0 5.4e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KOS20951.1 - 2.4e-07 31.2 0.0 3.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KOS20951.1 - 0.00086 18.8 0.0 0.0015 18.0 0.0 1.4 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KOS20951.1 - 0.0013 18.3 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS20951.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KOS20951.1 - 0.0045 17.0 0.2 0.0072 16.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS20951.1 - 0.016 14.9 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KOS20951.1 - 0.027 13.6 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KOS20951.1 - 0.028 14.0 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KOS20951.1 - 0.075 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KOS20951.1 - 0.087 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Dynamin_M PF01031.15 KOS20952.1 - 1.4e-112 375.3 0.0 2.8e-112 374.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KOS20952.1 - 4.1e-55 186.1 0.0 1.1e-54 184.7 0.0 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 KOS20952.1 - 7.8e-31 105.8 2.0 2.4e-30 104.2 0.8 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KOS20952.1 - 0.00032 20.6 0.0 0.0012 18.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KOS20952.1 - 0.019 15.4 0.0 0.06 13.8 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein zf-CCHC_4 PF14392.1 KOS20952.1 - 0.03 13.9 0.1 0.064 12.9 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Alk_phosphatase PF00245.15 KOS20954.1 - 5.4e-106 354.7 0.0 7.3e-106 354.3 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KOS20954.1 - 2.8e-05 23.6 0.0 5.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Ricin_B_lectin PF00652.17 KOS20955.1 - 3.1e-18 65.9 1.2 5.1e-09 36.2 0.2 4.0 2 2 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KOS20955.1 - 0.0015 18.8 0.0 5.2 7.4 0.0 3.5 2 2 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like DNA_ligase_A_M PF01068.16 KOS20956.1 - 2.1e-44 151.3 0.0 3.6e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KOS20956.1 - 2.4e-36 125.2 0.0 4.2e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KOS20956.1 - 5.3e-14 52.3 0.6 1.5e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KOS20956.1 - 1.3e-09 38.0 0.0 1.1e-06 28.6 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RNA_ligase PF09414.5 KOS20956.1 - 0.002 17.9 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_IV PF11411.3 KOS20956.1 - 0.0026 17.4 0.0 0.0082 15.8 0.0 1.9 1 0 0 1 1 1 1 DNA ligase IV PTCB-BRCT PF12738.2 KOS20956.1 - 0.065 13.1 0.0 0.9 9.4 0.0 2.4 2 0 0 2 2 2 0 twin BRCT domain mRNA_cap_enzyme PF01331.14 KOS20956.1 - 0.15 11.7 0.1 2 8.0 0.0 2.6 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain UPRTase PF14681.1 KOS20957.1 - 8e-74 247.3 0.0 9.1e-74 247.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KOS20957.1 - 1.9e-07 30.8 0.7 1.3e-06 28.1 0.5 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.12 KOS20957.1 - 0.03 13.4 0.7 1.3 8.1 0.2 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI PRTase_2 PF15609.1 KOS20957.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase CorA PF01544.13 KOS20958.1 - 5.4e-26 91.3 3.8 5.3e-21 74.9 1.6 2.6 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Brr6_like_C_C PF10104.4 KOS20958.1 - 0.059 12.8 0.2 0.22 11.0 0.1 1.9 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Myb_DNA-binding PF00249.26 KOS20960.1 - 1.2e-09 38.0 4.3 1.1e-06 28.5 0.9 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KOS20960.1 - 8.4e-09 35.4 1.0 3.3e-05 23.9 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain PAT1 PF09770.4 KOS20960.1 - 0.42 8.7 50.7 0.53 8.4 35.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Myb_DNA-bind_6 PF13921.1 KOS20961.1 - 0.00086 19.3 0.3 0.016 15.3 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KOS20961.1 - 0.024 14.6 0.2 0.37 10.8 0.2 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Sporozoite_P67 PF05642.6 KOS20961.1 - 0.81 7.4 10.8 1.2 6.9 7.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 KOS20961.1 - 1.3 8.8 35.2 0.21 11.3 21.6 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein SecE PF00584.15 KOS20962.1 - 4.3e-13 48.6 0.0 4.7e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex NAD_binding_10 PF13460.1 KOS20963.1 - 5.5e-15 55.8 0.0 3.1e-14 53.4 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KOS20963.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Glyco_hydro_16 PF00722.16 KOS20964.1 - 1.8e-46 157.7 1.5 2.8e-46 157.1 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 KOS20964.1 - 0.044 13.7 11.5 0.11 12.4 8.0 1.7 1 0 0 1 1 1 0 Chitin recognition protein SQS_PSY PF00494.14 KOS20965.1 - 4.6e-51 173.6 0.0 5.8e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase LEA_6 PF10714.4 KOS20965.1 - 0.058 13.1 1.8 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 SNF2_N PF00176.18 KOS20966.1 - 4.4e-69 232.5 0.0 6.1e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KOS20966.1 - 5.7e-26 90.5 0.1 1.7e-25 88.9 0.0 1.9 2 0 0 2 2 2 1 HIRAN domain Helicase_C PF00271.26 KOS20966.1 - 1.3e-11 44.1 0.0 4.6e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KOS20966.1 - 1e-06 28.6 9.1 1e-06 28.6 6.3 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS20966.1 - 4.5e-05 23.0 8.4 4.5e-05 23.0 5.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) UBA_4 PF14555.1 KOS20966.1 - 0.00055 19.4 0.1 0.099 12.1 0.0 2.7 2 0 0 2 2 2 1 UBA-like domain zf-C3HC4 PF00097.20 KOS20966.1 - 0.00056 19.5 9.2 0.0011 18.5 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS20966.1 - 0.0029 17.4 10.0 0.0029 17.4 6.9 1.9 2 0 0 2 2 2 1 Ring finger domain ETRAMP PF09716.5 KOS20966.1 - 0.24 11.3 2.0 0.74 9.8 1.4 1.8 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF2057 PF09829.4 KOS20966.1 - 1.1 8.8 10.7 1.8 8.2 6.4 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) zf-RING_5 PF14634.1 KOS20966.1 - 2.2 8.0 15.1 0.052 13.2 5.6 2.0 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KOS20966.1 - 3.6 7.5 7.2 7.6 6.4 5.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Dynamin_N PF00350.18 KOS20967.1 - 4e-18 65.8 0.1 8.2e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KOS20967.1 - 4.3e-10 39.5 0.1 1.7e-09 37.6 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KOS20967.1 - 4.3e-06 26.3 3.5 1.2e-05 24.8 0.8 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PMEI PF04043.10 KOS20967.1 - 0.007 16.2 0.1 0.023 14.6 0.1 1.8 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor AAA_29 PF13555.1 KOS20967.1 - 0.03 13.8 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FlgN PF05130.7 KOS20967.1 - 0.035 14.3 4.3 0.056 13.6 0.8 2.3 2 0 0 2 2 2 0 FlgN protein Miro PF08477.8 KOS20967.1 - 0.037 14.5 0.1 0.56 10.7 0.1 2.7 1 1 0 1 1 1 0 Miro-like protein AAA_18 PF13238.1 KOS20967.1 - 0.062 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain FH2 PF02181.18 KOS20967.1 - 0.068 12.0 0.5 0.16 10.8 0.2 1.7 2 0 0 2 2 2 0 Formin Homology 2 Domain Sigma54_activat PF00158.21 KOS20967.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Rpp20 PF12328.3 KOS20968.1 - 1.6e-25 89.4 0.0 2.2e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KOS20968.1 - 7e-18 63.9 0.0 1e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Alba Rogdi_lz PF10259.4 KOS20969.1 - 1.3e-56 191.6 0.0 1.5e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein CAP PF00188.21 KOS20970.1 - 1.8e-18 67.2 4.0 2.6e-18 66.7 2.8 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family GSu_C4xC__C2xCH PF09698.5 KOS20970.1 - 6.9 6.9 8.1 0.77 9.9 0.4 3.2 2 1 1 3 3 3 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) DUF3237 PF11578.3 KOS20971.1 - 5.5e-14 51.7 0.0 6.6e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Nup54 PF13874.1 KOS20972.1 - 4e-43 146.4 4.9 6.9e-43 145.6 0.3 2.2 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Mnd1 PF03962.10 KOS20972.1 - 0.00017 21.3 2.1 0.00017 21.3 1.5 2.1 1 1 1 2 2 2 1 Mnd1 family Nucleoporin_FG PF13634.1 KOS20972.1 - 0.012 15.7 14.3 0.02 15.1 9.9 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region UPF0184 PF03670.8 KOS20972.1 - 0.089 12.9 0.7 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) WD40_alt PF14077.1 KOS20972.1 - 0.19 11.4 0.6 0.83 9.3 0.1 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif APG6 PF04111.7 KOS20972.1 - 0.22 10.5 6.8 0.35 9.8 4.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 KOS20972.1 - 0.29 11.4 3.5 2 8.6 2.5 2.1 1 1 0 1 1 1 0 AAA domain FUSC PF04632.7 KOS20972.1 - 3.5 5.9 7.6 4.5 5.5 5.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3287 PF11690.3 KOS20972.1 - 3.9 7.5 5.7 1.2 9.2 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) CHCH PF06747.8 KOS20973.1 - 1.1e-08 34.7 10.4 3.5e-06 26.7 3.1 2.4 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.5 KOS20973.1 - 0.0011 18.6 10.8 0.16 11.7 0.3 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 KOS20973.1 - 0.35 10.9 9.1 2.2 8.3 5.2 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 KOS20973.1 - 0.96 9.5 11.4 2.5 8.1 0.6 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Radical_SAM PF04055.16 KOS20974.1 - 4.4e-14 53.0 0.0 6.7e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily GDC-P PF02347.11 KOS20975.1 - 4.5e-160 533.0 0.0 7.6e-147 489.4 0.0 2.7 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 KOS20975.1 - 1.3e-08 34.0 0.1 2.8e-05 23.0 0.0 2.4 2 1 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 KOS20975.1 - 4.7e-05 22.6 0.0 9.9e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase DUF4129 PF13559.1 KOS20975.1 - 0.075 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) NIPSNAP PF07978.8 KOS20976.1 - 1.8e-38 130.6 0.3 5.6e-29 100.1 0.1 2.1 2 0 0 2 2 2 2 NIPSNAP FSH1 PF03959.8 KOS20977.1 - 3e-53 180.4 0.0 3.7e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KOS20977.1 - 4e-06 26.8 4.9 9.3e-05 22.4 3.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS20977.1 - 8.7e-05 22.3 2.1 0.00014 21.6 1.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KOS20977.1 - 0.018 14.4 0.4 11 5.4 0.0 3.2 3 1 0 3 3 3 0 Phospholipase/Carboxylesterase PE-PPE PF08237.6 KOS20977.1 - 0.073 12.4 0.3 0.15 11.4 0.1 1.5 1 1 0 1 1 1 0 PE-PPE domain Sensor PF13796.1 KOS20978.1 - 0.089 12.3 13.8 0.15 11.6 9.6 1.3 1 0 0 1 1 1 0 Putative sensor DUF929 PF06053.6 KOS20978.1 - 1.2 8.1 5.1 2 7.4 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF929) SAM_2 PF07647.12 KOS20979.1 - 8.2e-15 54.4 0.0 1.6e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KOS20979.1 - 1.6e-14 54.1 0.0 2.9e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 KOS20979.1 - 6.8e-14 51.7 0.0 1.3e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Aminotran_1_2 PF00155.16 KOS20980.1 - 3.8e-58 197.1 0.0 5e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KOS20980.1 - 0.085 11.9 0.0 0.28 10.2 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase AMP-binding PF00501.23 KOS20981.1 - 1.5e-48 165.2 0.0 2e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS20981.1 - 0.00028 21.7 0.0 0.00072 20.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PIG-L PF02585.12 KOS20982.1 - 7.2e-22 78.2 1.8 3.4e-21 76.0 1.2 2.1 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Utp14 PF04615.8 KOS20984.1 - 0.041 12.0 15.2 0.059 11.5 10.6 1.1 1 0 0 1 1 1 0 Utp14 protein LMBR1 PF04791.11 KOS20984.1 - 0.071 11.6 1.0 0.094 11.2 0.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pex14_N PF04695.8 KOS20984.1 - 0.16 12.0 11.0 0.33 11.0 7.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Menin PF05053.8 KOS20984.1 - 0.16 10.1 9.0 0.22 9.6 6.2 1.1 1 0 0 1 1 1 0 Menin GCD14 PF08704.5 KOS20984.1 - 0.69 9.3 3.9 1.3 8.4 2.7 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF572 PF04502.8 KOS20984.1 - 1.1 8.4 15.2 1.7 7.7 10.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.2 KOS20984.1 - 4.2 4.9 14.3 5.6 4.5 9.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF498 PF04430.9 KOS20985.1 - 3.9e-24 84.3 0.0 5.5e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Nha1_C PF08619.5 KOS20986.1 - 2.1e-69 234.9 25.7 4.4e-65 220.6 12.3 2.1 1 1 1 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 KOS20986.1 - 1.2e-66 224.8 25.1 1.4e-66 224.5 17.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FlgD_ig PF13860.1 KOS20986.1 - 0.0083 15.8 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 1 FlgD Ig-like domain YrhC PF14143.1 KOS20986.1 - 0.37 10.7 4.0 0.19 11.6 0.2 2.4 2 0 0 2 2 2 0 YrhC-like protein Lyase_1 PF00206.15 KOS20988.1 - 4.8e-06 25.9 0.0 4.9e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 Lyase Lyase_1 PF00206.15 KOS20989.1 - 9.5e-69 231.9 0.0 1.4e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KOS20989.1 - 6.4e-23 80.5 0.1 1.2e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Fumarase C C-terminus WD40 PF00400.27 KOS20990.1 - 4.2e-12 45.4 1.1 0.71 9.8 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat WD40 PF00400.27 KOS20991.1 - 4e-54 178.6 30.2 1.3e-11 43.8 0.1 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KOS20991.1 - 0.0002 19.6 4.1 0.22 9.5 0.3 3.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Ribosomal_L18e PF00828.14 KOS20992.1 - 3.4e-25 88.9 0.2 3.4e-25 88.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Dimerisation PF08100.6 KOS20992.1 - 0.14 12.0 0.1 7.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Dimerisation domain 6PGD PF00393.14 KOS20994.1 - 3.9e-99 331.5 1.4 8.2e-91 304.2 0.2 2.1 1 1 1 2 2 2 2 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KOS20994.1 - 1.1e-49 168.3 0.0 1.6e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KOS20994.1 - 0.022 14.7 0.0 0.064 13.3 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_6 PF14259.1 KOS20995.1 - 0.00014 21.8 0.0 0.0025 17.7 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HPP PF04982.8 KOS20996.1 - 4.3e-37 126.6 10.3 4.3e-37 126.6 7.1 2.0 2 0 0 2 2 2 1 HPP family SSP160 PF06933.6 KOS20996.1 - 2.4 6.0 9.2 3.3 5.5 6.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ribosomal_L19e PF01280.15 KOS20997.1 - 1.9e-60 202.9 8.4 1.9e-60 202.9 5.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 KOS20997.1 - 0.1 11.8 0.8 0.098 11.8 0.6 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SHMT PF00464.14 KOS20998.1 - 2.8e-134 447.4 0.0 3.2e-134 447.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.12 KOS20998.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_S6 PF01250.12 KOS20999.1 - 3.2e-06 26.8 0.0 4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Cullin_binding PF03556.10 KOS21000.1 - 3.5e-29 101.3 3.9 3.9e-29 101.1 2.7 1.0 1 0 0 1 1 1 1 Cullin binding PTCB-BRCT PF12738.2 KOS21001.1 - 2.4e-38 129.8 2.2 1.9e-16 59.6 0.1 4.3 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.21 KOS21001.1 - 8.8e-33 112.3 0.0 1.9e-10 40.7 0.0 4.4 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain H-K_ATPase_N PF09040.6 KOS21001.1 - 1.3 9.2 5.2 3.2 7.9 3.6 1.6 1 0 0 1 1 1 0 Gastric H+/K+-ATPase, N terminal domain FUSC PF04632.7 KOS21002.1 - 0.15 10.4 2.4 0.16 10.3 1.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Chs3p PF12271.3 KOS21003.1 - 1.8e-115 384.9 17.8 4.7e-110 367.1 8.8 2.0 1 1 1 2 2 2 2 Chitin synthase III catalytic subunit DUF3382 PF11862.3 KOS21003.1 - 0.72 9.7 9.2 0.16 11.9 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) AAA PF00004.24 KOS21004.1 - 1.5e-10 41.3 0.1 2.6e-09 37.3 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KOS21004.1 - 4.3e-05 23.5 0.1 0.0003 20.8 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain Rad17 PF03215.10 KOS21004.1 - 0.00019 20.2 0.0 0.0011 17.7 0.0 2.1 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KOS21004.1 - 0.00027 21.7 0.0 0.00065 20.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KOS21004.1 - 0.00039 20.5 0.1 0.0022 18.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KOS21004.1 - 0.0032 16.2 0.0 0.0052 15.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 KOS21004.1 - 0.0097 15.8 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KOS21004.1 - 0.014 15.1 0.1 0.074 12.8 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 KOS21004.1 - 0.022 14.7 0.1 0.063 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KOS21004.1 - 0.028 14.1 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 KOS21004.1 - 0.034 13.0 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.7 KOS21004.1 - 0.072 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KOS21004.1 - 0.08 13.2 0.1 0.4 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KOS21004.1 - 0.12 12.5 0.0 0.39 10.9 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Rav1p_C PF12234.3 KOS21005.1 - 0.13 10.3 0.0 0.2 9.7 0.0 1.2 1 0 0 1 1 1 0 RAVE protein 1 C terminal Pirin PF02678.11 KOS21007.1 - 2.1e-25 88.6 1.7 5.8e-25 87.2 1.2 1.7 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 KOS21007.1 - 0.0019 17.6 1.9 0.049 13.1 0.2 3.0 2 1 0 2 2 2 1 Cupin domain MoaE PF02391.12 KOS21008.1 - 1.2e-29 102.4 0.1 1.5e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Pheromone PF08015.6 KOS21009.1 - 0.047 14.5 1.1 2.2 9.1 0.1 2.3 2 0 0 2 2 2 0 Fungal mating-type pheromone CD52 PF15116.1 KOS21009.1 - 4.2 7.2 8.7 11 5.8 0.9 2.2 2 0 0 2 2 2 0 CAMPATH-1 antigen Oxysterol_BP PF01237.13 KOS21010.1 - 4.9e-127 423.2 0.0 1.6e-126 421.5 0.0 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 KOS21010.1 - 4.6e-17 62.1 0.6 9.4e-11 41.9 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KOS21010.1 - 3.1e-16 59.3 0.3 3.4e-08 33.7 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KOS21010.1 - 7.7e-16 57.0 1.2 1.4e-06 27.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KOS21010.1 - 4.7e-15 55.2 1.6 3.2e-09 36.7 0.2 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS21010.1 - 4.6e-14 51.1 0.9 5.2e-05 23.1 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.24 KOS21010.1 - 2.3e-12 47.0 0.4 4.3e-12 46.1 0.3 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KOS21010.1 - 6.4e-10 39.2 1.0 1.8e-09 37.8 0.7 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KOS21010.1 - 6.9e-08 32.4 0.7 1.6e-07 31.3 0.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain AP_endonuc_2 PF01261.19 KOS21011.1 - 2.2e-29 102.2 1.8 2.2e-29 102.2 1.3 1.8 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel MDM1 PF15501.1 KOS21011.1 - 0.00061 18.8 5.4 0.00061 18.8 3.7 1.4 2 0 0 2 2 2 1 Nuclear protein MDM1 Pkinase PF00069.20 KOS21012.1 - 1.9e-15 56.7 0.0 3.2e-15 55.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS21012.1 - 2.3e-05 23.5 0.0 3.2e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase zf-H2C2_2 PF13465.1 KOS21013.1 - 6.9e-13 48.1 17.6 1.7e-06 27.9 1.4 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KOS21013.1 - 4.4e-10 39.2 22.7 0.0015 18.7 5.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS21013.1 - 5e-09 35.8 18.6 0.0022 18.1 4.4 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KOS21013.1 - 0.0013 18.5 9.3 0.3 11.0 0.0 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-CHCC PF10276.4 KOS21013.1 - 0.0098 15.7 2.0 2 8.3 0.2 2.9 2 0 0 2 2 2 1 Zinc-finger domain zf-C2H2_jaz PF12171.3 KOS21013.1 - 0.023 14.8 11.9 0.22 11.7 2.9 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KOS21013.1 - 0.039 14.0 10.4 0.24 11.5 3.9 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding GATA PF00320.22 KOS21013.1 - 0.044 13.1 1.5 0.13 11.6 1.0 1.9 1 1 0 1 1 1 0 GATA zinc finger zf-C2HC_2 PF13913.1 KOS21013.1 - 0.063 12.9 0.6 0.063 12.9 0.4 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type bZIP_1 PF00170.16 KOS21013.1 - 0.16 11.9 0.1 0.16 11.9 0.1 1.6 2 0 0 2 2 1 0 bZIP transcription factor zf-CHY PF05495.7 KOS21013.1 - 0.33 11.1 6.9 0.76 9.9 4.8 1.6 1 0 0 1 1 1 0 CHY zinc finger zf-RING_3 PF14369.1 KOS21013.1 - 0.38 10.8 6.0 12 5.9 0.1 3.1 2 1 1 3 3 3 0 zinc-finger DZR PF12773.2 KOS21013.1 - 0.41 10.5 5.4 3.1 7.6 3.7 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-met PF12874.2 KOS21013.1 - 0.42 10.8 10.0 5.4 7.3 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C3HC4_3 PF13920.1 KOS21013.1 - 0.54 9.9 4.2 12 5.6 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2225 PF09986.4 KOS21013.1 - 0.6 9.5 1.9 1.3 8.4 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zinc_ribbon_4 PF13717.1 KOS21013.1 - 0.78 9.4 4.9 9.1 6.0 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KOS21013.1 - 0.83 9.2 4.9 9.2 5.9 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 KOS21013.1 - 0.87 9.4 4.6 4.6 7.0 1.6 2.6 2 1 0 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.5 KOS21013.1 - 1.2 9.1 7.7 20 5.2 1.6 3.0 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.2 KOS21013.1 - 3.2 7.9 11.4 0.41 10.7 1.2 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) C1_4 PF07975.7 KOS21013.1 - 9.3 6.3 6.8 69 3.5 4.3 2.3 1 1 0 1 1 1 0 TFIIH C1-like domain DAGAT PF03982.8 KOS21014.1 - 2e-91 305.7 0.0 2.7e-91 305.3 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase KH_1 PF00013.24 KOS21015.1 - 0.00014 21.3 1.0 0.00025 20.6 0.3 1.6 2 0 0 2 2 2 1 KH domain MDM31_MDM32 PF08118.6 KOS21016.1 - 6.5e-185 615.3 0.4 7.3e-185 615.2 0.3 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Peptidase_M61 PF05299.7 KOS21016.1 - 0.0023 17.8 0.1 2.7 8.0 0.0 2.6 2 0 0 2 2 2 2 M61 glycyl aminopeptidase Mad3_BUB1_I PF08311.7 KOS21017.1 - 5.2e-42 142.5 0.3 7.5e-42 142.0 0.2 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Enolase_C PF00113.17 KOS21018.1 - 2.8e-151 502.5 0.0 3.7e-151 502.1 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KOS21018.1 - 1.7e-56 189.7 0.3 2.8e-56 189.0 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 KOS21018.1 - 0.017 14.0 0.1 0.061 12.2 0.1 1.8 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 KOS21018.1 - 0.02 15.4 0.1 0.055 14.0 0.0 1.9 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Hist_deacetyl PF00850.14 KOS21019.1 - 3.1e-77 259.9 0.0 4.5e-77 259.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain SUN PF03856.8 KOS21020.1 - 2.6e-84 282.4 13.0 3.3e-84 282.0 9.0 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Myosin_head PF00063.16 KOS21022.1 - 4.7e-245 814.8 1.3 9.3e-245 813.8 0.0 2.2 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KOS21022.1 - 1.4e-26 92.5 268.7 3.7e-23 81.2 75.2 5.9 1 1 3 4 4 4 4 Myosin tail Myosin_N PF02736.14 KOS21022.1 - 8.9e-06 25.2 0.1 2.2e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 KOS21022.1 - 0.33 11.0 0.0 0.33 11.0 0.0 4.7 5 0 0 5 5 5 0 AAA domain zf-PARP PF00645.13 KOS21023.1 - 9.9e-18 64.1 0.1 2.2e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Utp14 PF04615.8 KOS21023.1 - 0.56 8.3 42.4 0.66 8.0 29.4 1.0 1 0 0 1 1 1 0 Utp14 protein Peptidase_C12 PF01088.16 KOS21024.1 - 3.2e-57 193.1 0.0 3.9e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Pet191_N PF10203.4 KOS21025.1 - 2.5e-27 94.6 3.2 3.4e-27 94.2 2.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.7 KOS21025.1 - 0.059 12.9 0.5 0.1 12.2 0.4 1.3 1 0 0 1 1 1 0 PAN-like domain Metallophos PF00149.23 KOS21026.1 - 2e-09 37.1 0.0 2e-09 37.1 0.0 2.7 2 2 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KOS21026.1 - 2.4e-08 33.9 0.0 4.6e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MIP-T3 PF10243.4 KOS21026.1 - 0.14 10.5 59.2 0.21 10.0 41.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Abhydro_lipase PF04083.11 KOS21028.1 - 2.2e-21 74.9 0.0 4.7e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KOS21028.1 - 2.5e-19 69.7 0.6 1.1e-18 67.6 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KOS21028.1 - 1.2e-08 35.1 0.6 1.2e-08 35.1 0.4 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS21028.1 - 4.7e-05 23.1 0.0 0.00024 20.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KOS21028.1 - 0.00039 19.9 0.0 0.46 9.8 0.0 2.4 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Transaldolase PF00923.14 KOS21029.1 - 8.7e-97 323.7 0.4 1e-96 323.5 0.3 1.0 1 0 0 1 1 1 1 Transaldolase C5-epim_C PF06662.8 KOS21029.1 - 0.09 12.0 0.1 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus SNase PF00565.12 KOS21030.1 - 3e-66 220.4 0.8 1.5e-19 70.2 0.0 5.8 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KOS21030.1 - 2.4e-23 82.2 0.0 4.5e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 KOS21030.1 - 4.8e-06 25.8 0.0 1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Snf7 PF03357.16 KOS21031.1 - 1.4e-35 122.1 18.6 1.4e-35 122.1 12.9 1.4 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 KOS21031.1 - 0.0052 14.7 2.7 0.0063 14.4 1.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CaMBD PF02888.11 KOS21031.1 - 0.015 15.0 2.8 0.015 15.0 2.0 2.1 1 1 1 2 2 2 0 Calmodulin binding domain DUF3232 PF11554.3 KOS21031.1 - 0.15 11.9 2.0 0.17 11.7 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3232) Ist1 PF03398.9 KOS21031.1 - 0.27 10.6 6.8 0.44 9.9 4.7 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway PspA_IM30 PF04012.7 KOS21031.1 - 0.5 9.6 15.5 1.1 8.5 3.6 2.2 1 1 1 2 2 2 0 PspA/IM30 family DSBA PF01323.15 KOS21031.1 - 1.2 8.6 6.0 3.8 7.0 4.1 1.8 1 1 0 1 1 1 0 DSBA-like thioredoxin domain PP2C PF00481.16 KOS21032.1 - 2.5e-63 213.8 0.2 6e-50 170.0 0.1 3.3 1 1 0 2 2 2 2 Protein phosphatase 2C TolA PF06519.6 KOS21032.1 - 0.094 12.7 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 TolA C-terminal Zn_clus PF00172.13 KOS21033.1 - 5.5e-08 32.5 15.1 1.1e-07 31.6 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP20 PF00011.16 KOS21034.1 - 1.3e-16 60.2 0.2 3.1e-12 46.2 0.2 2.5 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Ribosomal_60s PF00428.14 KOS21034.1 - 0.33 11.3 8.9 0.25 11.7 4.4 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein LDB19 PF13002.2 KOS21035.1 - 3.7e-33 114.6 0.2 5.8e-33 113.9 0.1 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 KOS21035.1 - 1.1e-06 28.5 0.2 9.2e-05 22.2 0.0 3.2 4 0 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Corona_nucleoca PF00937.13 KOS21035.1 - 0.0059 15.5 4.3 0.011 14.7 3.0 1.3 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein Ribosomal_L5_C PF00673.16 KOS21037.1 - 6.2e-23 80.3 0.0 8.7e-23 79.8 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KOS21037.1 - 1.6e-21 75.8 0.1 4.4e-21 74.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 DnaJ PF00226.26 KOS21038.1 - 1.7e-16 59.7 0.7 3.2e-16 58.8 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 KOS21038.1 - 0.00038 20.4 1.2 0.00052 20.0 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Clr5 PF14420.1 KOS21039.1 - 9.7e-20 70.2 3.7 2.3e-19 68.9 2.6 1.7 1 0 0 1 1 1 1 Clr5 domain DUF2852 PF11014.3 KOS21039.1 - 0.043 13.7 0.4 0.095 12.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) TPR_12 PF13424.1 KOS21039.1 - 0.047 13.6 4.5 0.22 11.5 0.8 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KOS21039.1 - 0.35 10.7 3.0 1.7 8.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PITH PF06201.8 KOS21040.1 - 1.7e-23 83.0 0.0 7e-13 48.6 0.1 2.4 1 1 1 2 2 2 2 PITH domain Thioredoxin PF00085.15 KOS21040.1 - 4.2e-10 39.2 0.0 8.9e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.6 KOS21040.1 - 0.0052 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Macoilin PF09726.4 KOS21041.1 - 3.5 5.7 10.0 4.4 5.4 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein FA_desaturase PF00487.19 KOS21042.1 - 0.19 11.1 1.1 0.21 10.9 0.8 1.0 1 0 0 1 1 1 0 Fatty acid desaturase DUF2614 PF11023.3 KOS21042.1 - 2 8.2 7.9 2.4 7.9 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) RhoGAP PF00620.22 KOS21043.1 - 1.1e-43 148.5 0.3 3.8e-43 146.7 0.2 1.8 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 KOS21043.1 - 2.1e-10 40.7 0.0 4.3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KOS21043.1 - 3.1e-06 27.4 0.0 6.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PX PF00787.19 KOS21043.1 - 0.089 12.5 0.1 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 PX domain PH_8 PF15409.1 KOS21043.1 - 0.12 12.4 0.0 0.41 10.7 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4462 PF14692.1 KOS21043.1 - 0.17 11.1 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) WD40 PF00400.27 KOS21044.1 - 1.1e-47 158.2 20.1 9e-10 38.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KOS21044.1 - 0.00025 20.8 0.0 0.085 12.5 0.0 2.6 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A p450 PF00067.17 KOS21045.1 - 9.1e-43 146.4 0.0 1e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bax1-I PF01027.15 KOS21046.1 - 4.1e-48 163.7 29.6 4.9e-48 163.4 20.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.1 KOS21046.1 - 3.3 7.0 16.8 3 7.1 2.2 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Orbi_NS3 PF01616.11 KOS21046.1 - 4.9 6.0 7.2 0.87 8.5 0.2 2.5 3 0 0 3 3 3 0 Orbivirus NS3 Septin PF00735.13 KOS21047.1 - 2.2e-105 351.7 0.2 3.4e-105 351.1 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KOS21047.1 - 0.00034 20.5 0.0 0.00082 19.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KOS21047.1 - 0.00099 18.3 0.0 0.0022 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KOS21047.1 - 0.0027 17.5 3.0 1.7 8.4 0.0 3.0 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 KOS21047.1 - 0.033 13.6 0.2 0.08 12.3 0.1 1.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 KOS21047.1 - 0.044 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 KOS21047.1 - 0.11 12.5 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KOS21047.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 KOS21047.1 - 0.12 11.1 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_17 PF13207.1 KOS21047.1 - 0.12 13.2 0.2 0.12 13.2 0.1 2.9 2 2 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KOS21047.1 - 0.12 11.8 0.8 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family WD40 PF00400.27 KOS21048.1 - 5.2e-07 29.3 0.1 0.0077 16.0 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat RRM_1 PF00076.17 KOS21049.1 - 3.1e-16 58.7 0.1 4.4e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS21049.1 - 1.5e-09 37.7 0.0 2.5e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS21049.1 - 1.7e-06 27.7 0.0 5.8e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRA6 PF05084.8 KOS21049.1 - 9.1 5.7 10.0 13 5.2 6.9 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Cu_amine_oxid PF01179.15 KOS21050.1 - 1.5e-128 429.0 0.0 1.8e-128 428.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KOS21050.1 - 1.2e-05 25.2 0.0 3.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Gly_transf_sug PF04488.10 KOS21051.1 - 2.2e-13 50.4 0.0 5.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif AMP-binding PF00501.23 KOS21052.1 - 2.3e-85 286.5 0.0 2.8e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS21052.1 - 4.2e-17 62.8 0.1 1.4e-16 61.1 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TRAM_LAG1_CLN8 PF03798.11 KOS21053.1 - 9.9e-45 152.5 19.9 9.9e-45 152.5 13.8 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KOS21053.1 - 1.2e-18 66.3 0.2 3.5e-18 64.8 0.1 1.9 1 0 0 1 1 1 1 TRAM1-like protein MtN3_slv PF03083.11 KOS21053.1 - 0.11 12.3 5.5 0.071 12.9 0.4 2.8 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange DLIC PF05783.6 KOS21054.1 - 7e-05 21.6 0.2 0.027 13.1 0.0 2.2 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) Thioredox_DsbH PF03190.10 KOS21055.1 - 3.2e-54 183.0 0.0 5.2e-54 182.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Acyl-CoA_dh_C PF12806.2 KOS21055.1 - 0.0045 16.8 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Glyco_hydro_76 PF03663.9 KOS21055.1 - 0.018 14.4 0.1 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 Thioredoxin_7 PF13899.1 KOS21055.1 - 0.033 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like SUI1 PF01253.17 KOS21056.1 - 3.5e-21 74.7 0.4 7.4e-21 73.7 0.3 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 KOS21056.1 - 0.0024 17.7 0.1 0.0037 17.1 0.1 1.3 1 0 0 1 1 1 1 Transposon-encoded protein TnpV GEMIN8 PF15348.1 KOS21056.1 - 0.024 14.6 1.0 0.034 14.1 0.7 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 VWA_2 PF13519.1 KOS21057.1 - 5.2e-13 49.4 0.0 5.4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KOS21057.1 - 1.7e-07 31.1 0.1 2.5e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 KOS21057.1 - 2.1e-06 27.4 0.0 3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 KOS21057.1 - 0.0013 18.1 1.8 0.0048 16.3 1.2 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif Band_7 PF01145.20 KOS21058.1 - 3.1e-23 82.6 2.7 4.6e-23 82.0 1.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family E_Pc_C PF06752.7 KOS21058.1 - 0.023 14.1 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Methyltransf_11 PF08241.7 KOS21059.1 - 2.9e-13 50.1 0.0 8.3e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS21059.1 - 0.00071 19.3 0.0 0.002 17.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS21059.1 - 0.0061 16.9 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS21059.1 - 0.025 15.0 0.0 0.083 13.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KOS21059.1 - 0.067 13.7 0.1 0.32 11.5 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain Elongin_A PF06881.6 KOS21060.1 - 1.6e-20 73.4 0.0 4.5e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ubiquitin PF00240.18 KOS21061.1 - 4e-14 51.7 0.8 4.4e-14 51.6 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KOS21061.1 - 7.1e-08 32.0 0.3 7.5e-08 31.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KOS21061.1 - 0.00041 20.5 0.1 0.00047 20.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain HAD PF12710.2 KOS21062.1 - 2e-13 50.9 0.0 2.8e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KOS21062.1 - 0.039 14.1 0.1 0.33 11.1 0.1 2.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS21062.1 - 0.067 13.6 0.2 0.65 10.3 0.1 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TFIIF_beta PF02270.10 KOS21063.1 - 4.4e-62 210.3 0.0 5.6e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Tau95 PF09734.4 KOS21063.1 - 0.036 13.4 0.4 0.065 12.5 0.2 1.3 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit CENP-B_dimeris PF09026.5 KOS21063.1 - 6.5 7.0 10.4 1.1e+02 3.1 0.0 3.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain TPT PF03151.11 KOS21064.1 - 5.3e-31 107.3 13.5 5.3e-31 107.3 9.3 3.4 3 1 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 KOS21064.1 - 6.7e-06 25.2 18.0 6.7e-06 25.2 12.5 2.7 3 0 0 3 3 3 1 UAA transporter family DUF3357 PF11837.3 KOS21064.1 - 0.0011 18.8 0.8 0.045 13.5 0.0 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF3357) EamA PF00892.15 KOS21064.1 - 0.0013 18.7 38.2 0.045 13.8 5.1 3.9 3 1 0 3 3 3 2 EamA-like transporter family DUF2615 PF11027.3 KOS21064.1 - 0.0072 16.2 0.2 1.5 8.7 0.0 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2615) EphA2_TM PF14575.1 KOS21064.1 - 0.013 15.9 12.5 0.13 12.6 0.1 4.0 3 1 1 4 4 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2956 PF11169.3 KOS21064.1 - 0.027 14.4 1.1 0.38 10.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DAG1 PF05454.6 KOS21064.1 - 0.068 12.3 2.6 0.14 11.2 1.8 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4448 PF14610.1 KOS21064.1 - 0.074 12.5 0.4 0.15 11.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1183 PF06682.7 KOS21064.1 - 0.12 11.9 7.0 0.3 10.6 2.8 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1183) TMEM89 PF15098.1 KOS21064.1 - 0.19 11.7 0.9 1.4 8.9 0.4 2.4 2 0 0 2 2 2 0 TMEM89 protein family Viral_Beta_CD PF04530.7 KOS21064.1 - 0.39 10.8 1.8 2.7 8.1 0.1 3.0 3 0 0 3 3 3 0 Viral Beta C/D like family DUF2269 PF10027.4 KOS21064.1 - 0.85 9.3 11.0 0.36 10.5 4.7 2.5 2 1 1 3 3 3 0 Predicted integral membrane protein (DUF2269) DUF3938 PF13074.1 KOS21064.1 - 3.2 7.6 6.3 1.6 8.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) TMEM154 PF15102.1 KOS21064.1 - 3.6 7.2 12.1 0.058 13.1 1.8 2.5 1 1 1 2 2 2 0 TMEM154 protein family Erv26 PF04148.8 KOS21066.1 - 6.7e-86 287.0 0.9 8.4e-86 286.7 0.7 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3377 PF11857.3 KOS21066.1 - 0.017 14.7 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Cytochrom_C_asm PF01578.15 KOS21066.1 - 0.78 9.2 7.4 0.063 12.8 1.6 1.7 2 1 0 2 2 2 0 Cytochrome C assembly protein Peptidase_M20 PF01546.23 KOS21067.1 - 3.9e-26 91.7 0.1 6.2e-26 91.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KOS21067.1 - 1.3e-07 31.3 0.1 3.6e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain GTP_EFTU PF00009.22 KOS21068.1 - 9.3e-22 77.3 0.0 1.5e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KOS21068.1 - 9.1e-15 54.6 0.4 6.4e-14 51.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KOS21068.1 - 8e-11 41.8 1.9 1e-09 38.3 0.7 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Miro PF08477.8 KOS21068.1 - 0.00054 20.4 0.1 0.004 17.6 0.1 2.5 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KOS21068.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KOS21068.1 - 0.0022 17.5 0.1 0.007 15.9 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 KOS21068.1 - 0.0035 16.8 0.2 1.5 8.2 0.1 3.0 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 KOS21068.1 - 0.024 13.8 0.1 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KOS21068.1 - 0.025 14.4 0.1 0.066 13.0 0.1 1.7 1 0 0 1 1 1 0 Dynamin family F-box PF00646.28 KOS21069.1 - 1.9e-09 36.9 0.4 5.3e-09 35.4 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KOS21069.1 - 3.6e-07 29.8 3.0 5.6e-07 29.1 0.2 2.5 2 0 0 2 2 2 1 F-box-like V-ATPase_C PF03223.10 KOS21071.1 - 2e-111 372.4 0.0 2.2e-111 372.3 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 KOS21071.1 - 0.0031 17.7 0.6 0.011 16.0 0.1 2.1 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain Baculo_PEP_C PF04513.7 KOS21071.1 - 0.15 11.8 1.6 8.9 6.1 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rad60-SLD PF11976.3 KOS21072.1 - 2.2e-21 75.2 0.1 2.6e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KOS21072.1 - 2.2e-09 36.5 0.0 2.7e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Nup84_Nup100 PF04121.8 KOS21073.1 - 5.7e-59 199.5 0.0 9.9e-35 119.3 0.0 2.4 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 Mod_r PF07200.8 KOS21074.1 - 3.4e-06 27.0 0.1 5.6e-06 26.3 0.1 1.4 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein 4HBT PF03061.17 KOS21076.1 - 1.4e-10 41.1 0.0 2.8e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily CBF PF03914.12 KOS21077.1 - 4.6e-44 149.7 1.1 3.4e-43 146.9 0.0 2.7 2 0 0 2 2 2 1 CBF/Mak21 family Phosphodiest PF01663.17 KOS21078.1 - 1.3e-80 271.4 0.0 1.8e-80 270.9 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KOS21078.1 - 0.00031 20.0 0.1 0.36 9.9 0.0 2.4 2 0 0 2 2 2 2 Sulfatase PglZ PF08665.7 KOS21078.1 - 0.0023 17.6 0.0 0.025 14.2 0.0 2.4 2 0 0 2 2 2 1 PglZ domain PBP1_TM PF14812.1 KOS21078.1 - 0.2 11.9 0.1 0.2 11.9 0.1 4.3 4 1 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SNF2_N PF00176.18 KOS21079.1 - 1.5e-18 66.6 0.9 2.7e-18 65.7 0.1 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS21079.1 - 1.8e-11 43.7 0.0 3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 KOS21079.1 - 5.7e-07 29.1 4.4 9.7e-07 28.3 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS21079.1 - 9e-07 28.8 6.9 1.8e-06 27.8 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS21079.1 - 2.3e-05 24.0 6.3 4.2e-05 23.2 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KOS21079.1 - 3e-05 23.6 6.3 6.7e-05 22.5 4.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KOS21079.1 - 0.00035 20.1 5.2 0.00078 19.0 3.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KOS21079.1 - 0.0011 18.8 7.9 0.0066 16.2 5.8 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 KOS21079.1 - 0.024 14.1 5.3 0.073 12.5 3.7 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger NOA36 PF06524.7 KOS21079.1 - 0.076 12.2 13.1 0.13 11.4 9.1 1.4 1 0 0 1 1 1 0 NOA36 protein zf-RING_UBOX PF13445.1 KOS21079.1 - 0.076 12.7 0.9 0.16 11.7 0.2 1.9 1 1 1 2 2 2 0 RING-type zinc-finger YL1 PF05764.8 KOS21079.1 - 0.08 12.5 17.0 0.16 11.5 11.8 1.4 1 0 0 1 1 1 0 YL1 nuclear protein zf-Apc11 PF12861.2 KOS21079.1 - 0.15 11.9 3.1 0.42 10.4 2.2 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KOS21079.1 - 0.16 11.5 6.4 0.62 9.7 4.6 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain CDC45 PF02724.9 KOS21079.1 - 2.2 6.2 11.0 3.6 5.4 7.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_76 PF03663.9 KOS21080.1 - 2.4e-101 339.8 8.7 1.4e-80 271.4 1.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KOS21080.1 - 0.81 8.6 6.2 1.1 8.1 0.3 2.7 1 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 SR-25 PF10500.4 KOS21081.1 - 3.3 7.1 12.8 5.2 6.4 8.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF619 PF04768.8 KOS21082.1 - 5.7e-44 149.5 0.0 1e-43 148.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) AA_kinase PF00696.23 KOS21082.1 - 2.4e-29 102.5 0.0 5.3e-29 101.4 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.19 KOS21082.1 - 1.1e-27 96.6 0.0 2.7e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KOS21082.1 - 0.039 13.8 0.0 0.56 10.1 0.0 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.16 KOS21083.1 - 3.1e-32 110.0 0.7 3.7e-32 109.7 0.5 1.0 1 0 0 1 1 1 1 Synaptobrevin Fzo_mitofusin PF04799.8 KOS21083.1 - 0.084 12.2 1.3 0.077 12.3 0.4 1.3 1 1 0 1 1 1 0 fzo-like conserved region DUF2937 PF11157.3 KOS21083.1 - 0.085 12.1 1.1 0.083 12.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) Prominin PF05478.6 KOS21083.1 - 0.1 10.1 0.0 0.13 9.8 0.0 1.1 1 0 0 1 1 1 0 Prominin Sec20 PF03908.8 KOS21083.1 - 0.14 11.8 1.5 0.31 10.7 1.0 1.5 1 1 0 1 1 1 0 Sec20 Fasciclin PF02469.17 KOS21084.1 - 3.3e-34 117.6 0.0 2.3e-18 66.4 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain TPR_12 PF13424.1 KOS21085.1 - 1.6e-49 165.7 36.1 7.9e-14 51.3 0.3 7.6 4 2 5 9 9 9 9 Tetratricopeptide repeat TPR_14 PF13428.1 KOS21085.1 - 1.1e-30 103.3 44.8 0.018 15.6 0.2 12.3 8 1 4 12 12 12 10 Tetratricopeptide repeat TPR_10 PF13374.1 KOS21085.1 - 3e-30 103.2 36.0 7.2e-05 22.5 0.2 11.6 11 1 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 KOS21085.1 - 3.9e-29 100.0 34.0 2.1e-07 30.5 0.0 8.0 6 2 3 9 9 9 8 TPR repeat TPR_19 PF14559.1 KOS21085.1 - 9.5e-28 96.3 49.4 4.2e-06 27.0 0.1 10.4 4 2 7 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 KOS21085.1 - 4.8e-27 94.0 36.2 5.4e-06 26.9 0.0 7.7 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 KOS21085.1 - 1.1e-26 90.5 30.1 0.00072 19.2 0.0 12.4 12 1 0 12 12 12 6 Tetratricopeptide repeat TPR_7 PF13176.1 KOS21085.1 - 3e-25 85.9 32.7 0.0014 18.2 0.4 12.1 11 1 1 12 12 12 6 Tetratricopeptide repeat Apc3 PF12895.2 KOS21085.1 - 4e-23 81.3 21.5 3.2e-06 27.1 0.6 7.3 2 2 5 8 8 8 8 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KOS21085.1 - 6.7e-22 76.1 23.7 0.00055 19.4 0.1 11.1 10 1 0 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 KOS21085.1 - 8.3e-22 75.2 22.6 0.008 15.8 0.2 11.4 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_6 PF13174.1 KOS21085.1 - 1.8e-16 59.3 37.1 0.37 11.3 0.3 11.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_17 PF13431.1 KOS21085.1 - 1e-15 56.5 19.5 0.035 14.2 0.0 9.8 11 0 0 11 11 8 3 Tetratricopeptide repeat TPR_20 PF14561.1 KOS21085.1 - 8.9e-15 54.5 37.5 0.17 12.0 0.0 10.9 3 3 8 11 11 11 5 Tetratricopeptide repeat TPR_9 PF13371.1 KOS21085.1 - 1.4e-10 40.8 10.3 0.031 14.1 0.2 5.8 2 2 4 6 6 6 3 Tetratricopeptide repeat PPR PF01535.15 KOS21085.1 - 2.9e-09 36.2 0.9 2.1 8.5 0.0 8.2 10 0 0 10 10 9 1 PPR repeat Foie-gras_1 PF11817.3 KOS21085.1 - 0.00018 21.0 12.0 0.38 10.1 0.1 5.4 4 2 2 6 6 6 1 Foie gras liver health family 1 Paf67 PF10255.4 KOS21085.1 - 0.00031 19.7 0.1 0.42 9.4 0.0 3.6 3 1 0 4 4 4 1 RNA polymerase I-associated factor PAF67 DUF4248 PF14053.1 KOS21085.1 - 0.0046 16.5 5.4 1.9 8.0 0.0 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF4248) PPR_3 PF13812.1 KOS21085.1 - 0.01 16.0 5.4 1.9e+02 2.7 0.0 7.2 9 0 0 9 9 6 0 Pentatricopeptide repeat domain TPR_4 PF07721.9 KOS21085.1 - 0.025 14.9 36.3 1.8 9.2 0.0 10.3 13 1 0 13 13 8 0 Tetratricopeptide repeat Clathrin PF00637.15 KOS21085.1 - 0.058 12.9 3.8 2.5 7.6 0.5 4.3 3 3 1 4 4 4 0 Region in Clathrin and VPS PMSR PF01625.16 KOS21085.1 - 0.13 12.1 0.6 13 5.6 0.0 2.6 1 1 1 2 2 2 0 Peptide methionine sulfoxide reductase PPR_2 PF13041.1 KOS21085.1 - 0.15 12.0 0.9 66 3.5 0.0 4.6 5 0 0 5 5 3 0 PPR repeat family ATG16 PF08614.6 KOS21085.1 - 0.18 11.5 11.5 0.35 10.6 0.9 3.5 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) PPR_1 PF12854.2 KOS21085.1 - 0.2 11.1 0.2 47 3.5 0.0 3.9 5 0 0 5 5 5 0 PPR repeat Sel1 PF08238.7 KOS21085.1 - 0.68 10.6 7.0 3.5 8.4 0.1 4.4 5 0 0 5 5 3 0 Sel1 repeat DUF2225 PF09986.4 KOS21085.1 - 0.85 9.0 4.6 8.4 5.7 0.1 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Glyco_trans_2_3 PF13632.1 KOS21086.1 - 4.3e-46 157.0 7.8 4.3e-46 157.0 5.4 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KOS21086.1 - 6.2e-07 29.4 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KOS21086.1 - 4.8e-06 26.3 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KOS21086.1 - 0.0025 17.1 0.1 0.0078 15.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 KOS21087.1 - 1.7e-19 69.8 1.7 2.7e-19 69.1 1.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TaqI_C PF12950.2 KOS21087.1 - 0.01 15.5 0.1 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Cyclase PF04199.8 KOS21088.1 - 4e-14 52.6 0.4 8.4e-14 51.6 0.3 1.5 1 1 0 1 1 1 1 Putative cyclase DUF22 PF01629.11 KOS21088.1 - 0.038 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF22 TSA PF03249.8 KOS21089.1 - 0.095 11.2 2.1 0.1 11.1 1.5 1.2 1 0 0 1 1 1 0 Type specific antigen E_Pc_C PF06752.7 KOS21089.1 - 0.8 9.1 3.8 1.3 8.4 2.6 1.4 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus SH3_1 PF00018.23 KOS21090.1 - 1.6e-05 24.2 0.0 3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KOS21090.1 - 0.0062 16.1 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ycf1 PF05758.7 KOS21090.1 - 1.3 6.6 14.2 1.7 6.2 9.9 1.3 1 0 0 1 1 1 0 Ycf1 Tom22 PF04281.8 KOS21091.1 - 2.1e-44 150.3 0.1 2.5e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4055 PF13264.1 KOS21091.1 - 0.02 14.9 0.1 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) ELFV_dehydrog PF00208.16 KOS21092.1 - 3.8e-57 193.6 0.0 6e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KOS21092.1 - 2.3e-22 78.4 0.0 2.7e-17 61.6 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 KOS21092.1 - 0.00083 18.9 0.0 0.0032 17.0 0.0 2.0 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AAR2 PF05282.6 KOS21093.1 - 6.5e-45 153.6 0.0 9.5e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 AAR2 protein NBP1 PF08537.5 KOS21094.1 - 0.076 12.2 1.1 0.085 12.0 0.1 1.6 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 DUF1682 PF07946.9 KOS21094.1 - 0.16 10.7 4.7 0.19 10.5 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FAM165 PF14981.1 KOS21094.1 - 9 5.8 9.5 17 5.0 6.6 1.5 1 0 0 1 1 1 0 FAM165 family Ribosomal_L32e PF01655.13 KOS21095.1 - 7.8e-51 170.7 1.0 7.8e-51 170.7 0.7 1.3 2 0 0 2 2 2 1 Ribosomal protein L32 Ribosomal_S9 PF00380.14 KOS21096.1 - 1.2e-39 135.3 0.2 1.3e-39 135.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 KOS21096.1 - 0.053 11.0 0.0 0.061 10.8 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Pkinase PF00069.20 KOS21097.1 - 2.8e-61 206.9 0.0 4e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS21097.1 - 1.1e-44 152.4 0.0 1.9e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS21097.1 - 0.005 15.8 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like A_deaminase PF00962.17 KOS21098.1 - 5.2e-19 68.3 0.0 1.6e-18 66.7 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase DUF1212 PF06738.7 KOS21099.1 - 3.6e-55 186.4 3.0 4.6e-51 173.0 0.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KOS21099.1 - 4.9e-19 68.5 25.7 8.9e-11 41.8 0.3 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF3815) Med15 PF09606.5 KOS21099.1 - 0.054 11.6 27.3 0.08 11.1 18.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1180 PF06679.7 KOS21100.1 - 2.8 7.7 5.3 3.1 7.6 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) AA_permease PF00324.16 KOS21101.1 - 4.6e-119 397.8 50.0 5.7e-119 397.5 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KOS21101.1 - 1.5e-29 102.8 55.2 1.9e-29 102.4 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 KOS21102.1 - 5.9e-90 301.6 17.1 8.6e-90 301.1 11.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YfhO PF09586.5 KOS21102.1 - 0.037 12.0 1.6 0.059 11.3 1.1 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO PBP1_TM PF14812.1 KOS21102.1 - 0.38 11.0 2.8 0.67 10.2 2.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4140 PF13600.1 KOS21103.1 - 0.0011 19.3 6.2 0.0084 16.5 0.3 2.5 3 0 0 3 3 3 2 N-terminal domain of unknown function (DUF4140) ABC_tran PF00005.22 KOS21104.1 - 8.8e-49 165.3 0.0 1.5e-26 93.3 0.0 3.9 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KOS21104.1 - 1.6e-12 47.1 0.6 0.00021 20.6 0.0 4.3 3 2 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KOS21104.1 - 4.3e-12 46.6 7.5 0.00017 21.6 0.5 4.2 2 2 0 3 3 3 3 AAA domain AAA_23 PF13476.1 KOS21104.1 - 4e-08 33.8 0.4 0.00045 20.5 0.0 2.6 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KOS21104.1 - 1.2e-07 31.0 0.1 0.00037 19.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KOS21104.1 - 1.3e-07 32.4 0.1 0.0069 17.1 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 KOS21104.1 - 1.4e-07 30.9 0.4 0.0064 15.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Chromo PF00385.19 KOS21104.1 - 1.4e-07 31.0 0.0 2.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.18 KOS21104.1 - 7e-07 29.2 0.0 0.0071 16.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KOS21104.1 - 8.3e-06 26.2 0.0 0.012 16.0 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_15 PF13175.1 KOS21104.1 - 9e-06 24.9 0.0 0.67 8.9 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KOS21104.1 - 9.5e-06 25.7 0.5 0.3 11.2 0.0 3.7 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 KOS21104.1 - 1.7e-05 24.6 0.0 0.3 11.0 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KOS21104.1 - 2.1e-05 24.1 2.5 0.36 10.2 0.1 4.0 4 0 0 4 4 4 2 AAA-like domain AAA_33 PF13671.1 KOS21104.1 - 0.00011 22.1 0.0 0.63 9.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KOS21104.1 - 0.00026 20.6 0.1 0.39 10.4 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KOS21104.1 - 0.00057 19.8 0.0 0.03 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KOS21104.1 - 0.00083 18.2 0.5 0.18 10.5 0.1 2.4 2 0 0 2 2 2 1 ArgK protein DUF87 PF01935.12 KOS21104.1 - 0.001 18.9 1.3 0.38 10.5 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 NACHT PF05729.7 KOS21104.1 - 0.0014 18.3 0.1 1.1 8.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 KOS21104.1 - 0.0014 18.9 0.0 0.19 12.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KOS21104.1 - 0.0016 18.5 0.1 2.8 8.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_13 PF13166.1 KOS21104.1 - 0.0033 15.9 0.1 1.4 7.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 KOS21104.1 - 0.0037 17.0 0.0 0.15 11.8 0.0 2.9 3 0 0 3 3 3 1 Dynamin family AAA_25 PF13481.1 KOS21104.1 - 0.0047 16.3 0.0 4 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KOS21104.1 - 0.0063 16.7 0.1 4.7 7.4 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KOS21104.1 - 0.0076 15.7 0.0 0.8 9.1 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 KOS21104.1 - 0.0077 15.8 0.2 5.5 6.5 0.0 3.3 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.1 KOS21104.1 - 0.017 15.0 0.0 2.9 7.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain DUF3584 PF12128.3 KOS21104.1 - 0.023 12.0 0.9 2.4 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Arch_ATPase PF01637.13 KOS21104.1 - 0.049 13.3 0.1 10 5.7 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase DUF815 PF05673.8 KOS21104.1 - 0.053 12.4 0.1 2.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MutS_V PF00488.16 KOS21104.1 - 0.064 12.6 0.3 5.4 6.3 0.0 2.5 2 0 0 2 2 2 0 MutS domain V cobW PF02492.14 KOS21104.1 - 0.068 12.6 0.2 15 4.9 0.0 2.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 KOS21104.1 - 0.084 11.9 0.8 5.3 6.0 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin ATP-synt_ab PF00006.20 KOS21104.1 - 0.097 12.1 0.3 5.3 6.4 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 KOS21104.1 - 0.1 12.1 0.7 1.5 8.3 0.1 2.9 4 0 0 4 4 3 0 AAA domain AAA_16 PF13191.1 KOS21104.1 - 0.1 12.5 3.3 2.1 8.2 0.1 3.5 3 1 0 3 3 3 0 AAA ATPase domain NTPase_1 PF03266.10 KOS21104.1 - 0.13 11.9 0.3 22 4.6 0.2 2.9 2 0 0 2 2 2 0 NTPase zf-DHHC PF01529.15 KOS21105.1 - 3.4e-39 134.0 1.8 3.4e-39 134.0 1.2 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.12 KOS21105.1 - 0.31 10.5 7.0 0.12 11.8 0.1 2.1 2 0 0 2 2 2 0 Yip1 domain DUF4074 PF13293.1 KOS21106.1 - 0.049 13.8 0.1 13 6.1 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4074) HisKA_3 PF07730.8 KOS21106.1 - 0.066 13.5 1.0 0.13 12.6 0.7 1.5 1 0 0 1 1 1 0 Histidine kinase zf-His_Me_endon PF05551.6 KOS21106.1 - 0.071 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding loop region of homing endonuclease ACC_epsilon PF13822.1 KOS21106.1 - 5 7.5 10.6 3.3 8.1 3.1 2.4 1 1 1 2 2 2 0 Acyl-CoA carboxylase epsilon subunit PNP_UDP_1 PF01048.15 KOS21107.1 - 1.1e-11 44.2 0.2 5e-11 42.0 0.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily UbiA PF01040.13 KOS21108.1 - 1.9e-18 66.6 9.0 2.6e-18 66.1 6.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3767 PF12597.3 KOS21108.1 - 0.63 9.7 5.2 0.11 12.2 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) Ribosomal_S16 PF00886.14 KOS21109.1 - 1.6e-25 88.5 0.1 2.1e-25 88.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 NAD_binding_8 PF13450.1 KOS21111.1 - 4.5e-12 45.8 0.0 1.7e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KOS21111.1 - 3.8e-07 29.2 1.6 0.0002 20.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.19 KOS21111.1 - 4.7e-05 22.6 2.2 0.17 10.9 0.0 3.2 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 KOS21111.1 - 0.0011 18.8 0.0 0.0049 16.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS21111.1 - 0.0052 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KOS21111.1 - 0.026 14.1 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KOS21111.1 - 0.045 12.8 0.1 0.098 11.7 0.0 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 KOS21111.1 - 0.14 11.9 1.8 3.1 7.5 0.0 3.4 2 2 2 4 4 4 0 FAD-NAD(P)-binding Gly_transf_sug PF04488.10 KOS21112.1 - 5.5e-14 52.4 0.0 2.4e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif oligo_HPY PF08352.7 KOS21112.1 - 0.0021 18.3 0.2 0.028 14.7 0.0 2.5 2 0 0 2 2 2 1 Oligopeptide/dipeptide transporter, C-terminal region TcdA_TcdB PF12919.2 KOS21112.1 - 0.044 12.2 0.3 0.093 11.1 0.1 1.5 1 1 1 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Ribosomal_L35Ae PF01247.13 KOS21113.1 - 1.9e-40 136.5 0.4 2.1e-40 136.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KOS21113.1 - 0.0015 18.3 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain G6PD_C PF02781.11 KOS21114.1 - 1.1e-133 444.6 0.0 1.4e-133 444.2 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KOS21114.1 - 1.9e-62 210.7 0.0 3e-62 210.1 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain CZB PF13682.1 KOS21114.1 - 0.1 12.7 0.2 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain Med14 PF08638.6 KOS21115.1 - 2.4e-64 216.1 0.0 3.8e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 Amino_oxidase PF01593.19 KOS21116.1 - 4e-15 55.8 1.5 1.1e-06 27.9 0.1 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KOS21116.1 - 9.3e-12 44.7 0.2 2.8e-11 43.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KOS21116.1 - 6.2e-09 35.2 0.4 1.3e-06 27.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KOS21116.1 - 0.00063 20.0 0.1 0.065 13.6 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KOS21116.1 - 0.0019 17.3 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 KOS21116.1 - 0.0086 14.7 0.1 0.014 14.0 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 KOS21116.1 - 0.0088 16.1 0.0 0.04 13.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS21116.1 - 0.02 14.6 0.4 0.22 11.2 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KOS21116.1 - 0.056 13.3 0.1 0.19 11.5 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 KOS21116.1 - 0.11 10.8 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family SSP160 PF06933.6 KOS21116.1 - 1.3 6.9 7.9 1.7 6.4 5.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-CCCH_2 PF14608.1 KOS21117.1 - 3.6e-10 39.4 49.6 3.4e-06 26.8 5.3 5.4 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 KOS21117.1 - 0.027 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Aminotran_1_2 PF00155.16 KOS21118.1 - 5.7e-10 38.6 0.0 8.7e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KOS21118.1 - 7.2e-05 21.5 0.0 0.00012 20.7 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 KOS21118.1 - 0.052 12.5 0.0 0.73 8.8 0.0 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family RIC1 PF07064.8 KOS21119.1 - 7.1e-79 264.9 0.1 9.6e-79 264.4 0.0 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 KOS21119.1 - 0.00034 20.3 2.2 1.8 8.5 0.1 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat CK_II_beta PF01214.13 KOS21120.1 - 8.7e-71 237.2 0.2 8.7e-71 237.2 0.1 1.4 2 0 0 2 2 2 1 Casein kinase II regulatory subunit RR_TM4-6 PF06459.7 KOS21120.1 - 0.25 11.1 4.7 0.34 10.7 1.0 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PAP2 PF01569.16 KOS21121.1 - 2.3e-18 66.1 1.2 5.2e-18 64.9 0.1 2.0 2 1 0 2 2 2 1 PAP2 superfamily Ribosomal_L2_C PF03947.13 KOS21122.1 - 4e-24 84.8 0.2 3e-23 82.0 0.1 2.3 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KOS21122.1 - 4.7e-24 84.1 0.5 9.8e-24 83.1 0.3 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain HAS-barrel PF09378.5 KOS21122.1 - 0.11 12.3 0.0 0.8 9.6 0.0 2.2 2 0 0 2 2 2 0 HAS barrel domain Ocular_alb PF02101.10 KOS21122.1 - 0.16 10.5 0.1 0.25 9.9 0.1 1.2 1 0 0 1 1 1 0 Ocular albinism type 1 protein DAO PF01266.19 KOS21123.1 - 7.1e-13 48.1 4.0 5.6e-09 35.3 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KOS21123.1 - 3.1e-10 39.6 0.0 4.4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KOS21123.1 - 3.4e-06 27.2 0.0 7.8e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KOS21123.1 - 1.6e-05 24.1 0.1 8.2e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 KOS21123.1 - 0.00065 18.4 2.1 0.25 9.8 0.1 2.4 3 0 0 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.9 KOS21123.1 - 0.0025 16.3 2.3 0.43 8.9 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.1 KOS21123.1 - 0.0027 17.6 1.6 0.0033 17.4 0.2 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KOS21123.1 - 0.004 16.9 1.6 0.043 13.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KOS21123.1 - 0.0052 15.7 3.0 0.051 12.4 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KOS21123.1 - 0.0088 15.9 0.6 0.044 13.6 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS21123.1 - 0.024 15.0 0.6 21 5.5 0.2 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KOS21123.1 - 0.12 11.1 2.3 0.11 11.3 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain PEP-utilisers_N PF05524.8 KOS21124.1 - 0.051 13.3 0.2 0.06 13.1 0.1 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Ribosomal_L34e PF01199.13 KOS21125.1 - 2.3e-38 130.3 3.1 3.1e-38 129.8 2.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.3 KOS21125.1 - 2.1 8.0 7.2 2.5 7.8 0.2 2.7 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain PI-PLC-X PF00388.14 KOS21126.1 - 7.3e-44 148.6 0.0 1.1e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KOS21126.1 - 1.4e-28 99.2 0.0 2.2e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 KOS21126.1 - 0.052 13.4 0.2 0.51 10.2 0.1 2.3 2 0 0 2 2 2 0 C2 domain TRAPPC10 PF12584.3 KOS21128.1 - 1e-21 76.9 0.0 2.2e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 KOS21128.1 - 0.065 12.7 0.1 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Foie gras liver health family 1 Aldo_ket_red PF00248.16 KOS21129.1 - 3.7e-41 140.8 0.0 4.3e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S27e PF01667.12 KOS21130.1 - 2.5e-28 97.3 6.8 3.1e-28 97.0 4.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KOS21130.1 - 0.029 14.2 1.4 0.033 14.0 0.9 1.2 1 0 0 1 1 1 0 IBR domain RNR_inhib PF08591.5 KOS21131.1 - 8.5e-20 71.4 0.0 1.7e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor PRP38 PF03371.10 KOS21132.1 - 6.3e-61 204.9 0.0 7.7e-61 204.6 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Paf1 PF03985.8 KOS21132.1 - 0.0015 17.4 3.6 0.0015 17.4 2.5 1.1 1 0 0 1 1 1 1 Paf1 DUF1509 PF07420.6 KOS21132.1 - 0.31 10.2 4.0 0.45 9.7 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Daxx PF03344.10 KOS21132.1 - 1.1 7.6 15.2 1.4 7.2 10.5 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KOS21132.1 - 1.7 6.6 13.5 2.2 6.1 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KOS21132.1 - 2 6.2 11.0 2.2 6.0 7.6 1.1 1 0 0 1 1 1 0 Nop14-like family TEX19 PF15553.1 KOS21132.1 - 9.2 6.1 8.1 17 5.2 5.6 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 E2R135 PF11570.3 KOS21133.1 - 0.12 12.5 1.1 0.15 12.1 0.8 1.3 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 SIP1 PF04938.7 KOS21134.1 - 0.75 9.1 3.3 16 4.7 0.0 2.8 4 0 0 4 4 4 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Amidase PF01425.16 KOS21135.1 - 2.3e-105 352.9 0.3 2.9e-105 352.6 0.2 1.0 1 0 0 1 1 1 1 Amidase Abhydrolase_6 PF12697.2 KOS21136.1 - 1.7e-24 86.9 5.5 1.7e-24 86.9 3.8 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS21136.1 - 3.8e-16 59.1 0.0 3.5e-15 56.0 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 KOS21136.1 - 1.6e-09 37.4 0.1 3.3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 KOS21136.1 - 1.8e-08 34.2 0.0 1.4e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KOS21136.1 - 4.9e-05 23.6 0.1 0.00013 22.3 0.1 1.7 1 0 0 1 1 1 1 Thioesterase domain PTPlike_phytase PF14566.1 KOS21136.1 - 0.00011 22.2 0.8 0.0002 21.4 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate PGAP1 PF07819.8 KOS21136.1 - 0.0036 16.9 0.0 0.07 12.7 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein Y_phosphatase PF00102.22 KOS21136.1 - 0.0087 15.4 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LCAT PF02450.10 KOS21136.1 - 0.053 12.4 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Peptidase_M20 PF01546.23 KOS21137.1 - 6.5e-18 64.9 0.4 1.1e-17 64.2 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KOS21137.1 - 2.3e-17 62.7 0.0 4.8e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.11 KOS21138.1 - 1.2e-46 159.0 47.0 1.2e-46 159.0 32.6 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS21139.1 - 4.8e-22 78.1 24.2 6.5e-13 48.0 3.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF2686 PF10887.3 KOS21139.1 - 0.028 13.1 0.0 0.048 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) Pkinase PF00069.20 KOS21140.1 - 2e-61 207.4 0.0 2.7e-38 131.6 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KOS21140.1 - 9.2e-28 97.0 0.0 5.9e-20 71.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KOS21140.1 - 2.4e-14 53.2 0.0 5.6e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 KOS21140.1 - 1.3e-07 30.8 0.0 4.4e-05 22.5 0.0 2.9 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 KOS21140.1 - 5.6e-06 26.2 0.0 0.0049 16.6 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family PAS PF00989.19 KOS21140.1 - 0.0008 19.1 0.0 0.0022 17.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 KOS21140.1 - 0.0031 17.8 0.0 0.0082 16.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain Kdo PF06293.9 KOS21140.1 - 0.0087 15.1 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KOS21140.1 - 0.062 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Got1 PF04178.7 KOS21141.1 - 8.6e-31 106.4 17.3 1.1e-30 106.1 12.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 KOS21141.1 - 0.059 12.3 0.0 0.1 11.5 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M50 HLH PF00010.21 KOS21142.1 - 1e-12 47.5 0.0 3.3e-12 45.9 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3734 PF12536.3 KOS21142.1 - 0.065 13.3 0.9 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 Patatin phospholipase CDK5_activator PF03261.10 KOS21143.1 - 0.27 10.5 5.7 0.3 10.3 3.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Shisa PF13908.1 KOS21143.1 - 1.3 9.1 8.0 1.6 8.8 5.6 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF605 PF04652.11 KOS21143.1 - 2 7.7 9.5 2.4 7.4 6.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF966 PF06136.8 KOS21143.1 - 4.8 6.4 9.1 5.7 6.2 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) GKAP PF03359.8 KOS21143.1 - 9.6 5.7 7.8 11 5.5 5.4 1.1 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein La PF05383.12 KOS21144.1 - 4.3e-18 64.8 0.0 6.8e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 La domain zf-C2H2_4 PF13894.1 KOS21146.1 - 0.00011 22.2 7.6 0.008 16.4 0.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KOS21146.1 - 0.00015 21.9 6.8 0.5 10.8 0.0 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-Di19 PF05605.7 KOS21146.1 - 5.8 7.1 8.1 27 5.0 0.0 3.1 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding NPR3 PF03666.8 KOS21147.1 - 1.5e-128 429.1 0.2 1.5e-128 429.1 0.1 2.1 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 PAT1 PF09770.4 KOS21147.1 - 0.88 7.7 54.4 0.29 9.3 34.5 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Choline_kinase PF01633.15 KOS21148.1 - 3.8e-48 163.8 0.0 5.9e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KOS21148.1 - 2.1e-12 47.2 0.9 3.8e-12 46.4 0.3 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KOS21148.1 - 2.2e-06 27.0 0.0 3.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 KOS21148.1 - 0.00039 19.1 0.0 0.00072 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) TFIIS_C PF01096.13 KOS21149.1 - 8.8e-20 70.0 3.3 8.8e-20 70.0 2.3 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KOS21149.1 - 0.00021 20.8 0.8 0.00021 20.8 0.6 2.7 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 KOS21149.1 - 0.0046 16.7 9.4 0.043 13.6 0.3 2.8 2 1 0 2 2 2 2 Transposase zinc-ribbon domain DUF2387 PF09526.5 KOS21149.1 - 0.013 15.4 3.5 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Elf1 PF05129.8 KOS21149.1 - 0.015 14.9 6.0 0.15 11.7 0.1 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Desulfoferrod_N PF06397.7 KOS21149.1 - 0.036 13.4 0.3 2.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Zn_ribbon_recom PF13408.1 KOS21149.1 - 0.045 14.0 2.5 0.5 10.6 0.0 2.6 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-DNL PF05180.7 KOS21149.1 - 0.41 10.4 3.1 25 4.6 0.0 3.3 3 0 0 3 3 3 0 DNL zinc finger DZR PF12773.2 KOS21149.1 - 1.3 8.9 9.9 0.5 10.2 0.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 KOS21149.1 - 2.1 7.8 4.9 4.9 6.7 0.1 2.9 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit OrfB_Zn_ribbon PF07282.6 KOS21149.1 - 2.7 7.7 5.7 12 5.5 0.3 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-Mss51 PF13824.1 KOS21149.1 - 5.4 6.9 7.6 4.3 7.2 0.5 2.4 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Nudix_N_2 PF14803.1 KOS21149.1 - 8.6 6.1 7.9 14 5.4 2.3 2.9 2 1 0 2 2 2 0 Nudix N-terminal Ank_2 PF12796.2 KOS21150.1 - 8.3e-09 35.6 0.0 1.9e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KOS21150.1 - 3.8e-08 33.6 0.0 2.9e-05 24.4 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS21150.1 - 2.1e-07 30.5 0.1 0.015 15.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 KOS21150.1 - 9.4e-07 28.3 0.1 0.049 13.4 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KOS21150.1 - 3.8e-05 23.7 0.1 0.92 9.8 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) GPI2 PF06432.6 KOS21151.1 - 5.8e-115 383.4 0.0 7.3e-115 383.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase CFEM PF05730.6 KOS21152.1 - 9.6e-12 44.5 12.2 2.2e-11 43.4 8.5 1.6 1 0 0 1 1 1 1 CFEM domain DUF605 PF04652.11 KOS21152.1 - 0.04 13.3 14.4 0.047 13.0 10.0 1.1 1 0 0 1 1 1 0 Vta1 like Metallophos PF00149.23 KOS21153.1 - 2.6e-10 40.0 0.0 3.7e-05 23.1 0.0 2.4 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KOS21153.1 - 5.3e-10 39.3 0.0 1.4e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Med31 PF05669.7 KOS21154.1 - 3e-37 126.4 0.5 3.3e-37 126.3 0.3 1.0 1 0 0 1 1 1 1 SOH1 Herpes_U5 PF05999.6 KOS21154.1 - 0.11 11.0 0.6 0.16 10.5 0.3 1.3 1 1 0 1 1 1 0 Herpesvirus U5-like family RAI16-like PF10257.4 KOS21154.1 - 0.12 11.2 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein WD40 PF00400.27 KOS21155.1 - 7.6e-13 47.7 17.4 1.1e-05 25.1 0.8 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat RWD PF05773.17 KOS21155.1 - 7.7e-06 25.7 0.1 1.6e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 KOS21155.1 - 3.4 7.5 13.6 0.43 10.4 6.4 1.8 2 0 0 2 2 2 0 Ring finger domain Abhydrolase_6 PF12697.2 KOS21157.1 - 5.4e-32 111.4 0.9 6.6e-32 111.2 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS21157.1 - 1.7e-11 44.0 0.1 9.5e-11 41.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS21157.1 - 4e-08 33.1 0.1 2.8e-06 27.0 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KOS21157.1 - 9.2e-07 28.2 0.0 0.00062 19.0 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.13 KOS21157.1 - 3.4e-05 23.2 0.0 0.00017 20.9 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Thioesterase PF00975.15 KOS21157.1 - 0.0025 18.0 0.0 0.004 17.4 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain BAAT_C PF08840.6 KOS21157.1 - 0.0026 17.4 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.5 KOS21157.1 - 0.063 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein PGAP1 PF07819.8 KOS21157.1 - 0.082 12.4 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein PhoPQ_related PF10142.4 KOS21157.1 - 0.096 11.1 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Peptidase_S15 PF02129.13 KOS21157.1 - 0.14 11.5 0.0 1.4 8.2 0.0 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 KOS21157.1 - 0.15 11.4 0.0 6.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase (FSH1) PHP PF02811.14 KOS21159.1 - 3.5e-08 33.4 0.0 4.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 PHP domain Hist_deacetyl PF00850.14 KOS21160.1 - 9.3e-61 205.8 0.1 1.4e-60 205.2 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain APG9 PF04109.11 KOS21160.1 - 0.48 9.2 0.1 0.74 8.6 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg9 TGT PF01702.13 KOS21162.1 - 1.4e-86 289.6 0.0 1.7e-86 289.3 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Mit_ribos_Mrp51 PF11709.3 KOS21163.1 - 2.1e-61 207.8 0.0 2.5e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.13 KOS21164.1 - 2.1e-55 185.6 0.1 3.1e-55 185.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal S17 RPAP2_Rtr1 PF04181.8 KOS21165.1 - 2.2e-19 69.2 0.0 3.4e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_1 PF00018.23 KOS21166.1 - 4.7e-12 45.0 0.1 8.3e-12 44.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KOS21166.1 - 1.3e-11 43.9 0.1 3.7e-11 42.4 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KOS21166.1 - 3.4e-11 42.4 0.0 6e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TFIIA PF03153.8 KOS21166.1 - 0.052 13.4 18.2 0.081 12.8 12.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.7 KOS21166.1 - 0.43 9.7 13.1 0.67 9.1 9.1 1.2 1 0 0 1 1 1 0 NOA36 protein Glyco_transf_20 PF00982.16 KOS21167.1 - 7.5e-162 539.0 0.1 9.8e-162 538.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KOS21167.1 - 9.1e-43 145.8 0.0 6.5e-42 143.0 0.0 2.0 2 0 0 2 2 2 1 Trehalose-phosphatase Peptidase_C14 PF00656.17 KOS21168.1 - 2.7e-70 236.8 0.0 3.5e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain WW PF00397.21 KOS21169.1 - 2.5e-08 33.6 4.3 9e-08 31.8 3.0 2.0 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.4 KOS21169.1 - 0.0018 18.3 8.0 0.0035 17.4 5.5 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) PI-PLC-X PF00388.14 KOS21171.1 - 1.6e-57 193.0 0.0 2.5e-57 192.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KOS21171.1 - 1.2e-34 118.8 0.0 1.9e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KOS21171.1 - 0.022 14.7 0.1 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like HisKA_3 PF07730.8 KOS21171.1 - 0.21 11.9 2.0 4.9 7.5 0.4 3.2 3 0 0 3 3 3 0 Histidine kinase DUF2732 PF10809.3 KOS21172.1 - 0.067 12.7 0.1 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) Sgf11 PF08209.6 KOS21172.1 - 0.16 11.2 7.4 0.023 14.0 2.3 1.7 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Pro_isomerase PF00160.16 KOS21173.1 - 2.3e-48 164.3 0.0 2.6e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.8 KOS21174.1 - 1.3e-45 156.0 2.4 2.5e-42 145.3 1.6 2.5 2 1 0 2 2 2 2 Signal peptide peptidase DUF1119 PF06550.6 KOS21174.1 - 3.8 6.5 16.3 29 3.6 5.9 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1119) ACPS PF01648.15 KOS21175.1 - 4.8e-08 32.8 0.0 8.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Mito_fiss_reg PF05308.6 KOS21175.1 - 0.13 11.6 0.2 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Thaumatin PF00314.12 KOS21176.1 - 2.1e-43 148.2 2.3 2.5e-43 148.0 1.6 1.1 1 0 0 1 1 1 1 Thaumatin family HSP70 PF00012.15 KOS21177.1 - 1.3e-10 39.8 0.1 1.7e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein zf-SAP30 PF13866.1 KOS21177.1 - 0.0016 18.0 0.1 0.0035 16.9 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 KOS21177.1 - 0.005 15.4 0.1 0.06 11.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Hexokinase_1 PF00349.16 KOS21178.1 - 5.1e-63 212.1 0.1 1.5e-62 210.6 0.0 1.7 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 KOS21178.1 - 3e-62 209.9 0.0 4.5e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase LacAB_rpiB PF02502.13 KOS21178.1 - 0.091 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Ribose/Galactose Isomerase Acetyltransf_1 PF00583.19 KOS21179.1 - 1e-07 31.8 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS21179.1 - 0.06 13.5 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS21179.1 - 0.062 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GBS_Bsp-like PF08481.5 KOS21179.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 GBS Bsp-like repeat SR-25 PF10500.4 KOS21179.1 - 9.9 5.5 29.5 4.7 6.6 9.4 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3716 PF12511.3 KOS21180.1 - 6.8e-13 48.0 4.6 1.3e-12 47.0 3.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DEAD PF00270.24 KOS21181.1 - 6.4e-46 155.9 0.0 4.5e-44 149.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS21181.1 - 1.3e-28 98.6 0.0 2.8e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS21181.1 - 0.00015 21.6 0.0 0.00076 19.3 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KOS21181.1 - 0.001 17.5 0.0 0.051 11.9 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 KOS21181.1 - 0.0036 17.2 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DUF2443 PF10398.4 KOS21181.1 - 0.009 15.7 0.3 0.025 14.3 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2443) Glyoxalase_3 PF13468.1 KOS21181.1 - 0.03 14.2 0.1 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain FtsK_SpoIIIE PF01580.13 KOS21181.1 - 0.063 12.7 0.7 0.18 11.2 0.0 2.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF3734 PF12536.3 KOS21181.1 - 0.12 12.5 0.7 30 4.7 0.0 3.2 3 0 0 3 3 3 0 Patatin phospholipase Ribosomal_L13 PF00572.13 KOS21183.1 - 3.8e-38 130.4 0.0 5.2e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 tRNA-synt_1c PF00749.16 KOS21184.1 - 8.4e-81 271.0 0.0 1.1e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain TPR_1 PF00515.23 KOS21185.1 - 8.8e-17 59.9 8.7 5.1e-08 32.1 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS21185.1 - 1.6e-16 58.7 5.7 5.7e-06 25.8 0.0 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 KOS21185.1 - 3.1e-15 55.5 4.8 4.5e-11 42.2 0.2 3.5 1 1 2 3 3 3 2 TPR repeat TPR_8 PF13181.1 KOS21185.1 - 6.5e-12 44.3 4.2 0.00027 20.4 0.0 4.8 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KOS21185.1 - 6.9e-12 45.1 2.4 1.2e-07 31.5 0.1 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat PB1 PF00564.19 KOS21185.1 - 8e-10 38.2 0.1 1.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_6 PF13174.1 KOS21185.1 - 9.9e-10 38.2 0.6 0.35 11.4 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KOS21185.1 - 5.9e-08 31.9 1.5 4.2e-06 26.1 0.1 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KOS21185.1 - 4.9e-07 29.4 1.0 0.0014 18.6 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KOS21185.1 - 1.7e-06 28.5 5.3 6.3e-05 23.5 0.1 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KOS21185.1 - 7.6e-06 26.1 2.7 0.0032 17.9 0.0 3.9 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KOS21185.1 - 0.00062 19.5 0.7 0.91 9.4 0.1 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KOS21185.1 - 0.00088 19.3 2.7 0.0026 17.8 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KOS21185.1 - 0.016 15.6 0.1 80 4.1 0.0 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AUX_IAA PF02309.11 KOS21185.1 - 0.017 14.8 2.8 0.029 14.1 1.9 1.3 1 0 0 1 1 1 0 AUX/IAA family Med19 PF10278.4 KOS21185.1 - 0.026 14.1 4.6 0.051 13.2 3.2 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Hid1 PF12722.2 KOS21185.1 - 3.5 5.2 5.5 4.6 4.7 3.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Phos_pyr_kin PF08543.7 KOS21186.1 - 4.6e-67 225.8 0.3 5.9e-67 225.4 0.2 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KOS21186.1 - 2.3e-35 122.2 0.5 8.7e-33 113.8 0.3 2.2 1 1 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 KOS21186.1 - 1.3e-05 24.5 0.4 0.00011 21.4 0.0 2.2 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 KOS21186.1 - 0.039 13.2 0.7 0.063 12.5 0.5 1.3 1 0 0 1 1 1 0 Carbohydrate kinase Pyr_redox_2 PF07992.9 KOS21187.1 - 2.9e-26 92.6 0.1 5.4e-16 59.0 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS21187.1 - 1.1e-13 51.4 0.0 5.5e-12 45.9 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KOS21187.1 - 0.0013 18.8 0.1 1.5 8.8 0.1 2.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Uricase PF01014.13 KOS21188.1 - 1.5e-83 277.7 0.2 8.3e-44 149.0 0.1 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.1 KOS21189.1 - 7.8e-133 442.6 0.4 5e-132 439.9 0.1 2.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KOS21189.1 - 5.9e-89 296.9 1.6 2.8e-87 291.4 0.2 3.2 2 1 2 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KOS21189.1 - 7.8e-41 138.6 0.2 2.4e-39 133.8 0.0 2.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KOS21189.1 - 6.4e-28 96.4 0.7 1.8e-26 91.8 0.1 3.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 KOS21189.1 - 9.4e-13 47.7 6.4 3.3e-12 45.9 4.5 2.0 1 0 0 1 1 1 1 Hr1 repeat HEAT_2 PF13646.1 KOS21189.1 - 0.0047 17.1 0.6 2.2 8.6 0.0 4.4 4 0 0 4 4 4 1 HEAT repeats Uds1 PF15456.1 KOS21189.1 - 0.0069 16.3 5.9 0.017 15.1 4.1 1.6 1 0 0 1 1 1 1 Up-regulated During Septation IncA PF04156.9 KOS21189.1 - 0.99 8.9 4.3 1.9 8.0 3.0 1.4 1 0 0 1 1 1 0 IncA protein Ribosomal_L36e PF01158.13 KOS21191.1 - 4.1e-41 138.9 5.6 4.7e-41 138.7 3.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 KOS21191.1 - 0.03 13.4 0.2 0.034 13.2 0.1 1.1 1 0 0 1 1 1 0 LemA family Transcrip_act PF04949.8 KOS21191.1 - 0.095 12.3 2.2 0.11 12.1 1.5 1.2 1 0 0 1 1 1 0 Transcriptional activator MRP-L28 PF09812.4 KOS21191.1 - 0.1 12.3 1.7 0.12 12.1 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 14-3-3 PF00244.15 KOS21192.1 - 9.9e-113 375.0 2.0 1.2e-112 374.6 1.4 1.1 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 KOS21192.1 - 0.028 14.3 0.5 8.4 6.4 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat SYCE1 PF15233.1 KOS21192.1 - 0.069 13.0 1.8 0.12 12.2 0.1 2.0 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Lipase_3 PF01764.20 KOS21193.1 - 1.7e-28 99.0 0.0 2.2e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KOS21193.1 - 7.2e-06 26.0 3.2 1.7e-05 24.8 2.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS21193.1 - 4.5e-05 23.2 0.1 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KOS21193.1 - 0.0019 18.4 0.1 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 KOS21193.1 - 0.027 14.0 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KOS21193.1 - 0.029 13.7 0.0 0.51 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 KOS21193.1 - 0.27 10.7 0.1 0.43 10.1 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein Syja_N PF02383.13 KOS21194.1 - 4.1e-82 275.5 0.0 5.8e-82 275.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 KOS21194.1 - 2.2e-20 73.6 0.1 5.8e-20 72.2 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family peroxidase PF00141.18 KOS21196.1 - 7.8e-49 166.2 0.0 1.3e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Suf PF05843.9 KOS21197.1 - 1.2e-05 25.2 4.3 0.0017 18.1 0.1 3.0 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KOS21197.1 - 4.6e-05 23.6 1.2 0.39 11.4 0.0 5.7 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 KOS21197.1 - 0.00077 19.7 0.2 0.031 14.6 0.0 3.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KOS21197.1 - 0.00085 19.9 3.5 0.078 13.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS21197.1 - 0.044 13.5 0.2 8.8 6.3 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TUG-UBL1 PF11470.3 KOS21198.1 - 8.2e-25 86.5 0.2 1.9e-24 85.3 0.0 1.7 2 0 0 2 2 2 1 GLUT4 regulating protein TUG RBD PF02196.10 KOS21198.1 - 0.00024 20.7 0.2 0.00094 18.8 0.1 1.9 2 0 0 2 2 2 1 Raf-like Ras-binding domain DUF4294 PF14127.1 KOS21198.1 - 0.0038 16.8 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4294) Rad60-SLD PF11976.3 KOS21198.1 - 0.031 13.9 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Mucin PF01456.12 KOS21198.1 - 0.12 12.2 1.5 0.18 11.5 1.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Proteasome PF00227.21 KOS21199.1 - 1.8e-43 148.0 0.0 2.1e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Thioredoxin PF00085.15 KOS21200.1 - 3.5e-23 81.2 0.0 4.3e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KOS21200.1 - 4.3e-07 30.1 0.0 3.2e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 KOS21200.1 - 2.8e-06 26.9 0.0 3.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KOS21200.1 - 0.00037 20.5 0.0 0.0061 16.6 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KOS21200.1 - 0.0011 19.0 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KOS21200.1 - 0.0042 16.6 0.0 0.0064 16.0 0.0 1.4 1 1 0 1 1 1 1 Redoxin Glutaredoxin PF00462.19 KOS21200.1 - 0.024 14.6 0.1 0.064 13.2 0.1 1.7 1 1 0 1 1 1 0 Glutaredoxin TrbC_Ftype PF09673.5 KOS21200.1 - 0.068 12.7 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein AhpC-TSA PF00578.16 KOS21200.1 - 0.08 12.6 0.0 0.32 10.6 0.0 1.7 1 1 1 2 2 2 0 AhpC/TSA family WD40 PF00400.27 KOS21201.1 - 6e-35 117.8 2.2 4.1e-09 35.9 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KOS21201.1 - 0.0052 16.5 0.1 36 4.1 0.0 4.2 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region AA_permease_2 PF13520.1 KOS21202.1 - 6.7e-57 192.9 41.9 8.2e-57 192.6 29.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KOS21202.1 - 3.6e-34 117.9 41.6 4.7e-34 117.5 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease INTS5_N PF14837.1 KOS21202.1 - 0.11 11.8 1.2 0.26 10.6 0.8 1.5 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus WD40 PF00400.27 KOS21203.1 - 9.6e-30 101.3 5.0 1.2e-11 44.0 0.1 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KOS21203.1 - 7.5e-19 67.4 0.1 2.3e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Med19 PF10278.4 KOS21204.1 - 0.012 15.3 4.6 0.014 15.1 3.2 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF612 PF04747.7 KOS21204.1 - 0.07 12.0 13.2 0.084 11.7 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF612 CAF-1_p150 PF11600.3 KOS21204.1 - 0.47 9.7 22.5 0.61 9.4 15.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CRISPR_assoc PF08798.6 KOS21204.1 - 1.2 8.8 6.2 1.4 8.5 4.3 1.1 1 0 0 1 1 1 0 CRISPR associated protein zf-RING_5 PF14634.1 KOS21205.1 - 0.0013 18.3 2.8 0.0045 16.6 1.9 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KOS21205.1 - 0.0084 16.1 0.5 0.0084 16.1 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS21205.1 - 0.022 14.4 2.3 0.064 12.9 1.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS21205.1 - 0.042 13.5 2.9 0.15 11.7 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Serglycin PF04360.7 KOS21205.1 - 0.044 13.5 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Serglycin zf-C3HC4_4 PF15227.1 KOS21205.1 - 0.079 12.8 2.8 0.29 11.0 0.2 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KOS21205.1 - 0.15 11.8 3.0 0.24 11.2 0.3 2.1 2 0 0 2 2 2 0 Ring finger domain C1_4 PF07975.7 KOS21205.1 - 0.16 12.0 3.5 1.2 9.1 1.9 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain FYVE PF01363.16 KOS21205.1 - 0.16 11.8 3.9 0.91 9.4 2.7 2.0 1 1 0 1 1 1 0 FYVE zinc finger Ribosomal_60s PF00428.14 KOS21205.1 - 2.1 8.7 5.8 0.65 10.4 1.8 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein eRF1_1 PF03463.10 KOS21206.1 - 2.4e-36 124.2 0.0 4.3e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 KOS21206.1 - 9.3e-23 81.0 0.0 1.5e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KOS21206.1 - 5.7e-16 58.7 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 Aldo_ket_red PF00248.16 KOS21207.1 - 7.2e-34 116.8 0.0 1e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3791 PF12668.2 KOS21207.1 - 0.13 11.8 0.0 6.1 6.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3791) Prp19 PF08606.6 KOS21208.1 - 8.2e-30 102.3 3.0 8.6e-30 102.2 0.9 1.9 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.27 KOS21208.1 - 1.7e-13 49.8 0.3 0.00034 20.3 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KOS21208.1 - 5.2e-06 25.5 0.0 0.00012 21.0 0.0 2.1 1 1 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.6 KOS21208.1 - 0.00013 21.7 0.0 0.51 10.0 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A OHCU_decarbox PF09349.5 KOS21209.1 - 1.3e-38 132.8 0.0 1.5e-38 132.6 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase DUF3659 PF12396.3 KOS21211.1 - 1.2e-111 364.4 46.2 8.1e-24 83.0 0.5 6.8 6 0 0 6 6 6 6 Protein of unknown function (DUF3659) RabGAP-TBC PF00566.13 KOS21212.1 - 1.2e-32 113.0 0.0 1.9e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ALIX_LYPXL_bnd PF13949.1 KOS21212.1 - 0.056 12.3 1.9 0.12 11.3 1.3 1.5 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV FA_desaturase PF00487.19 KOS21213.1 - 6e-26 91.4 15.9 9.4e-26 90.7 11.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KOS21213.1 - 5.1e-07 29.7 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) GST_C_2 PF13410.1 KOS21213.1 - 0.23 11.3 1.9 0.45 10.4 0.2 2.3 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain eIF2A PF08662.6 KOS21214.1 - 1.1e-39 136.1 1.6 4.5e-37 127.6 0.1 3.7 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 KOS21214.1 - 0.00016 21.1 0.0 0.00034 20.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS21214.1 - 0.00017 21.3 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KOS21214.1 - 0.00037 20.2 0.0 2.6 8.0 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat RRM_6 PF14259.1 KOS21214.1 - 0.005 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.19 KOS21215.1 - 1.5e-133 445.9 8.8 1.8e-133 445.7 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-H2C2_5 PF13909.1 KOS21216.1 - 0.77 10.1 0.0 0.77 10.1 0.0 4.5 4 1 0 4 4 4 0 C2H2-type zinc-finger domain Pkinase PF00069.20 KOS21217.1 - 2.2e-43 148.2 0.0 3.1e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 KOS21217.1 - 2.5e-41 140.5 0.0 4.9e-41 139.5 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 KOS21217.1 - 9.8e-22 77.2 0.0 6.2e-21 74.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KOS21217.1 - 0.003 16.6 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KOS21217.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KOS21217.1 - 0.017 14.4 0.0 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PLDc_2 PF13091.1 KOS21218.1 - 1.3e-13 50.7 0.0 4.2e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KOS21218.1 - 0.0023 17.7 0.1 0.021 14.5 0.0 2.3 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.3 KOS21218.1 - 0.011 14.7 0.0 0.034 13.1 0.0 1.8 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB FMO-like PF00743.14 KOS21218.1 - 0.041 12.0 0.0 0.061 11.5 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like SWIB PF02201.13 KOS21219.1 - 7.5e-21 73.6 0.3 2.6e-20 71.8 0.1 2.0 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 KOS21219.1 - 7.6e-15 54.4 1.6 1.3e-14 53.6 1.1 1.4 1 0 0 1 1 1 1 DEK C terminal domain Methyltransf_PK PF05891.7 KOS21219.1 - 0.06 12.6 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Alpha_kinase PF02816.13 KOS21220.1 - 1.1e-32 113.2 0.0 1.4e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Alpha-kinase family APS_kinase PF01583.15 KOS21221.1 - 2.9e-72 241.4 0.0 3.6e-72 241.1 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 KOS21221.1 - 2.1e-07 30.9 0.0 3.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS21221.1 - 2.8e-06 28.1 0.0 4.2e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KOS21221.1 - 3.5e-05 24.1 0.0 5.7e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KOS21221.1 - 9.8e-05 21.6 0.0 0.00012 21.4 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.1 KOS21221.1 - 0.0054 16.7 0.5 0.018 15.0 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 KOS21221.1 - 0.009 15.1 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin PRK PF00485.13 KOS21221.1 - 0.017 14.6 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 KOS21221.1 - 0.029 13.9 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain 6PF2K PF01591.13 KOS21221.1 - 0.04 12.9 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CPT PF07931.7 KOS21221.1 - 0.073 12.6 0.1 0.15 11.6 0.1 1.9 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein CoaE PF01121.15 KOS21221.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase ADH_zinc_N_2 PF13602.1 KOS21222.1 - 2.1e-11 44.8 0.0 5.5e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KOS21222.1 - 1.1e-06 28.2 0.0 1.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KOS21222.1 - 1.7e-05 24.5 0.0 8.7e-05 22.2 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_18 PF00704.23 KOS21223.1 - 2.2e-52 178.5 0.1 1.9e-30 106.5 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 MFS_1 PF07690.11 KOS21224.1 - 1.4e-11 43.7 26.9 7.7e-10 38.0 10.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Aldo_ket_red PF00248.16 KOS21225.1 - 6.5e-50 169.5 0.0 7.3e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0261 PF06792.6 KOS21226.1 - 2.1e-143 477.6 0.1 2.5e-143 477.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) TIM-br_sig_trns PF09370.5 KOS21227.1 - 1.5e-125 417.6 0.7 1.7e-125 417.4 0.5 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 KOS21227.1 - 2.4e-07 30.2 2.3 6.2e-07 28.8 0.3 2.0 2 0 0 2 2 2 1 Nitronate monooxygenase PcrB PF01884.12 KOS21227.1 - 0.2 10.8 1.0 1.2 8.2 0.2 2.1 2 0 0 2 2 2 0 PcrB family WSC PF01822.14 KOS21228.1 - 1.3e-05 25.0 0.1 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 WSC domain Glyco_hydro_3 PF00933.16 KOS21229.1 - 2.2e-61 207.4 0.0 3.3e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KOS21229.1 - 3.8e-44 150.8 0.0 5.4e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KOS21229.1 - 1.8e-06 27.7 0.0 3.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4334 PF14232.1 KOS21230.1 - 7.3e-24 83.1 0.1 5.3e-23 80.4 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4334) GXWXG PF14231.1 KOS21230.1 - 6.7e-12 44.8 0.2 1.6e-11 43.6 0.1 1.6 1 1 0 1 1 1 1 GXWXG protein F-box PF00646.28 KOS21231.1 - 0.0042 16.6 0.1 0.017 14.7 0.1 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KOS21231.1 - 0.0084 15.8 0.2 0.019 14.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like Trypan_PARP PF05887.6 KOS21231.1 - 8.5 6.1 13.1 17 5.2 9.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF221 PF02714.10 KOS21232.1 - 1.7e-86 290.0 19.5 1.7e-86 290.0 13.5 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KOS21232.1 - 1.8e-41 141.3 1.9 1.8e-41 141.3 1.3 2.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KOS21232.1 - 3.3e-15 56.3 0.0 7.2e-15 55.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) Anoctamin PF04547.7 KOS21232.1 - 0.00042 19.0 0.0 0.00042 19.0 0.0 1.9 2 0 0 2 2 2 1 Calcium-activated chloride channel Zn_clus PF00172.13 KOS21234.1 - 4.2e-07 29.7 11.9 6.6e-07 29.1 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.3 KOS21234.1 - 0.13 11.5 12.7 0.47 9.7 1.4 2.5 2 0 0 2 2 2 0 Spt20 family zf-DHHC PF01529.15 KOS21234.1 - 0.17 11.2 6.5 6.1 6.2 0.0 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF3439 PF11921.3 KOS21234.1 - 2.8 7.7 8.0 0.19 11.4 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) YEATS PF03366.11 KOS21235.1 - 4.3e-22 77.6 0.0 7.9e-22 76.7 0.0 1.5 1 0 0 1 1 1 1 YEATS family Ran_BP1 PF00638.13 KOS21236.1 - 3.7e-44 149.7 1.8 3.7e-44 149.7 1.3 1.8 2 0 0 2 2 2 1 RanBP1 domain DUF1681 PF07933.9 KOS21236.1 - 0.00011 21.7 2.7 0.00011 21.7 1.8 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1681) Pox_Ag35 PF03286.9 KOS21236.1 - 5.9 6.3 23.2 0.59 9.6 7.1 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Apolipoprotein PF01442.13 KOS21237.1 - 0.0076 15.7 7.4 0.012 15.1 5.1 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DALR_2 PF09190.6 KOS21237.1 - 0.12 12.6 2.8 0.18 12.0 0.2 2.6 2 0 0 2 2 2 0 DALR domain DUF883 PF05957.8 KOS21237.1 - 0.59 10.5 10.5 1.8 9.0 0.2 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Phosducin PF02114.11 KOS21238.1 - 7.1e-13 47.8 0.0 1.1e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Phosducin FAM176 PF14851.1 KOS21238.1 - 0.19 11.4 8.4 1.6 8.3 0.4 2.3 2 0 0 2 2 2 0 FAM176 family Cwf_Cwc_15 PF04889.7 KOS21238.1 - 0.62 9.7 10.7 0.1 12.2 1.2 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.6 KOS21238.1 - 2.9 5.6 5.3 2 6.1 0.5 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen EAP30 PF04157.11 KOS21239.1 - 9.3e-52 175.3 0.0 2e-51 174.2 0.0 1.5 1 1 0 1 1 1 1 EAP30/Vps36 family DnaJ PF00226.26 KOS21240.1 - 7e-24 83.3 3.2 1.4e-23 82.3 2.2 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KOS21240.1 - 5.7e-18 64.5 0.0 1.3e-16 60.1 0.0 2.6 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KOS21240.1 - 2.7e-12 46.5 17.7 5.1e-12 45.6 12.2 1.5 1 0 0 1 1 1 1 DnaJ central domain UreE_N PF02814.10 KOS21240.1 - 0.0083 15.6 0.9 0.039 13.4 0.1 2.2 2 0 0 2 2 2 1 UreE urease accessory protein, N-terminal domain HypA PF01155.14 KOS21240.1 - 0.07 12.8 7.6 0.4 10.3 1.0 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-CHY PF05495.7 KOS21240.1 - 0.88 9.7 4.9 7 6.8 0.2 2.3 2 0 0 2 2 2 0 CHY zinc finger Glyco_transf_64 PF09258.5 KOS21241.1 - 2.5e-53 180.7 0.0 3.4e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glycos_transf_2 PF00535.21 KOS21241.1 - 0.019 14.6 0.2 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 CHZ PF09649.5 KOS21242.1 - 0.0024 17.0 0.1 0.0046 16.1 0.1 1.4 1 0 0 1 1 1 1 Histone chaperone domain CHZ DUF3659 PF12396.3 KOS21243.1 - 3e-18 65.2 1.3 8.9e-12 44.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) UPF0051 PF01458.12 KOS21243.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein family (UPF0051) DUF2076 PF09849.4 KOS21244.1 - 0.045 13.8 2.6 0.053 13.5 1.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) LZ_Tnp_IS481 PF13011.1 KOS21244.1 - 1.1 9.6 5.3 1.9 8.8 3.7 1.3 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 WD40 PF00400.27 KOS21246.1 - 9.6e-85 275.7 31.2 4.1e-16 58.1 1.3 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 KOS21246.1 - 2.1e-06 26.1 3.3 0.015 13.4 0.0 4.6 2 1 0 4 4 4 2 Nucleoporin Nup120/160 Gmad1 PF10647.4 KOS21246.1 - 1e-05 25.0 1.7 0.00024 20.6 0.0 2.5 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain eIF2A PF08662.6 KOS21246.1 - 2.2e-05 24.2 0.4 0.16 11.6 0.0 3.6 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KOS21246.1 - 4.1e-05 23.1 0.1 0.65 9.7 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat NLE PF08154.7 KOS21246.1 - 0.00021 21.2 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Proteasome_A_N PF10584.4 KOS21246.1 - 0.036 13.4 0.6 5.2 6.4 0.0 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature TFIIIC_delta PF12657.2 KOS21246.1 - 0.46 10.1 4.3 12 5.5 0.2 3.6 2 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term DASH_Spc19 PF08287.6 KOS21247.1 - 2.2e-39 134.5 1.8 3.4e-39 133.9 1.3 1.3 1 0 0 1 1 1 1 Spc19 Bac_luciferase PF00296.15 KOS21247.1 - 0.083 11.9 0.3 0.098 11.7 0.2 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase COG5 PF10392.4 KOS21247.1 - 0.13 12.2 1.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 Golgi transport complex subunit 5 PCI PF01399.22 KOS21248.1 - 2.4e-22 79.2 0.0 9.6e-22 77.2 0.0 2.1 1 0 0 1 1 1 1 PCI domain EST1_DNA_bind PF10373.4 KOS21248.1 - 0.034 13.3 0.2 1.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain SH3_1 PF00018.23 KOS21250.1 - 1.1e-09 37.4 0.1 2.1e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KOS21250.1 - 1.9e-07 30.4 0.0 3.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KOS21250.1 - 6.5e-07 28.8 0.0 1.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Sulfate_transp PF00916.15 KOS21250.1 - 0.01 14.9 1.5 0.01 14.9 1.1 2.0 1 1 1 2 2 2 1 Sulfate transporter family DUF1129 PF06570.6 KOS21250.1 - 2.4 7.4 5.1 2.5 7.3 2.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Thioredoxin PF00085.15 KOS21251.1 - 9.7e-28 95.9 0.2 1.7e-27 95.1 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 KOS21251.1 - 1.2e-07 31.7 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KOS21251.1 - 4.7e-05 23.0 0.0 6.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 KOS21251.1 - 0.00011 22.3 0.2 0.00054 20.1 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 KOS21251.1 - 0.00086 18.8 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KOS21251.1 - 0.00086 18.8 0.1 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 KOS21251.1 - 0.0027 17.6 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Rsm22 PF09243.5 KOS21252.1 - 7.2e-34 117.0 0.0 7e-33 113.8 0.0 2.4 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 DUF342 PF03961.8 KOS21252.1 - 5.5 5.2 10.0 2.1 6.6 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) WD40 PF00400.27 KOS21253.1 - 9.8e-24 82.3 7.3 1.6e-06 27.8 0.0 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat Methyltrn_RNA_3 PF02598.12 KOS21254.1 - 7.4e-83 278.2 0.0 8.4e-83 278.0 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase AAA_29 PF13555.1 KOS21254.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SpoU_methylase PF00588.14 KOS21254.1 - 0.12 12.1 0.0 7.4 6.4 0.0 2.3 2 0 0 2 2 2 0 SpoU rRNA Methylase family SCO1-SenC PF02630.9 KOS21255.1 - 3.8e-59 199.2 0.0 4.9e-59 198.8 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KOS21255.1 - 0.007 16.0 0.0 0.016 14.8 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KOS21255.1 - 0.018 14.5 0.0 0.36 10.3 0.0 2.2 1 1 0 1 1 1 0 Redoxin PHD PF00628.24 KOS21256.1 - 2.8e-11 42.9 12.0 5.5e-11 41.9 8.3 1.5 1 0 0 1 1 1 1 PHD-finger HMA PF00403.21 KOS21257.1 - 3.5e-10 39.8 0.0 6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 KOS21257.1 - 1.1e-09 38.5 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Serglycin PF04360.7 KOS21257.1 - 0.0059 16.3 0.5 0.0082 15.8 0.4 1.3 1 0 0 1 1 1 1 Serglycin Spore_II_R PF09551.5 KOS21259.1 - 0.11 12.5 9.0 0.043 13.8 3.5 2.3 2 1 1 3 3 3 0 Stage II sporulation protein R (spore_II_R) JHBP PF06585.6 KOS21259.1 - 0.12 11.1 1.3 0.52 9.0 0.9 1.9 1 1 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) DUF1215 PF06744.7 KOS21259.1 - 0.16 11.5 1.8 0.47 10.1 1.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1215) MgtE_N PF03448.12 KOS21259.1 - 0.17 12.1 8.2 0.35 11.2 5.7 1.6 1 0 0 1 1 1 0 MgtE intracellular N domain RapA_C PF12137.3 KOS21259.1 - 0.24 10.1 19.3 0.21 10.3 11.4 2.0 1 1 1 2 2 2 0 RNA polymerase recycling family C-terminal ATC_hydrolase PF14196.1 KOS21259.1 - 0.29 11.5 16.8 0.35 11.2 9.8 2.2 1 1 1 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Rsbr_N PF08678.5 KOS21259.1 - 0.33 10.8 5.5 0.68 9.8 3.8 1.6 1 0 0 1 1 1 0 Rsbr N terminal DUF445 PF04286.7 KOS21259.1 - 0.37 10.2 15.8 0.31 10.5 10.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Antimicrobial_2 PF08023.7 KOS21259.1 - 0.4 11.0 5.1 3.6e+02 1.6 3.5 4.0 1 1 0 1 1 1 0 Frog antimicrobial peptide SRI PF08236.6 KOS21259.1 - 0.54 10.2 14.4 1 9.3 7.9 2.5 2 1 0 2 2 1 0 SRI (Set2 Rpb1 interacting) domain SseC PF04888.7 KOS21259.1 - 0.55 9.5 25.2 0.037 13.3 13.4 1.8 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family REF PF05755.7 KOS21259.1 - 0.56 9.9 8.2 1.3 8.7 1.1 2.2 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) HK97-gp10_like PF04883.7 KOS21259.1 - 1.6 9.7 20.2 0.82 10.6 1.6 3.2 1 1 2 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component CBFD_NFYB_HMF PF00808.18 KOS21259.1 - 3.6 7.7 18.2 1.2 9.2 2.3 3.2 2 1 1 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YtxH PF12732.2 KOS21259.1 - 7.7 6.9 20.6 4.3e+02 1.3 0.0 3.5 2 1 0 2 2 2 0 YtxH-like protein Parathyroid PF01279.12 KOS21260.1 - 0.079 13.5 1.1 0.092 13.3 0.7 1.0 1 0 0 1 1 1 0 Parathyroid hormone family HgmA PF04209.8 KOS21261.1 - 7e-168 558.3 0.0 8.1e-168 558.2 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Slu7 PF11708.3 KOS21262.1 - 0.0033 17.2 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor ABC2_membrane PF01061.19 KOS21266.1 - 1.4e-81 272.6 65.9 1.8e-43 148.1 13.6 3.6 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KOS21266.1 - 1.3e-30 105.0 7.6 2.3e-27 94.6 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 KOS21266.1 - 1.1e-12 48.3 0.0 2.5e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 KOS21266.1 - 2.8e-05 23.5 0.0 8.2e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KOS21266.1 - 0.00051 20.0 0.1 0.0011 18.9 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KOS21266.1 - 0.00098 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 KOS21266.1 - 0.0019 17.6 0.1 0.0062 16.0 0.1 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KOS21266.1 - 0.006 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KOS21266.1 - 0.011 15.2 0.1 0.028 13.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane_2 PF12679.2 KOS21266.1 - 0.018 13.8 34.3 0.02 13.7 2.5 3.6 3 1 0 3 3 3 0 ABC-2 family transporter protein AAA_17 PF13207.1 KOS21266.1 - 0.021 15.6 0.0 0.054 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KOS21266.1 - 0.023 15.0 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 KOS21266.1 - 0.024 13.8 0.0 0.51 9.5 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KOS21266.1 - 0.083 12.8 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KOS21266.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.2 KOS21266.1 - 6.1 5.7 61.7 0.23 10.4 20.5 4.5 2 2 1 3 3 3 0 ABC-2 family transporter protein Pkinase PF00069.20 KOS21267.1 - 1e-59 201.8 0.0 1.2e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS21267.1 - 4.3e-35 121.0 0.0 6.1e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS21267.1 - 2.7e-08 33.1 0.0 4e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DEAD PF00270.24 KOS21268.1 - 1.6e-40 138.3 0.0 7.4e-40 136.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS21268.1 - 4.1e-27 93.8 0.3 4.4e-26 90.5 0.1 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KOS21268.1 - 3.6e-05 22.7 0.0 4.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KOS21268.1 - 0.022 14.5 0.0 0.065 13.0 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Nop14 PF04147.7 KOS21268.1 - 0.071 11.0 18.9 0.1 10.5 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KOS21268.1 - 1.2 7.0 18.4 1.8 6.4 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.3 KOS21268.1 - 1.5 7.7 13.2 2.1 7.2 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nucleo_P87 PF07267.6 KOS21268.1 - 5.8 5.4 12.5 9 4.8 8.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1510 PF07423.6 KOS21268.1 - 6.6 6.0 13.1 10 5.3 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 KOS21268.1 - 6.6 5.0 18.4 9.6 4.5 12.7 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 KOS21268.1 - 8.4 4.9 30.0 14 4.2 20.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 KOS21268.1 - 8.4 5.2 12.7 14 4.5 8.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SAD_SRA PF02182.12 KOS21269.1 - 5.2e-05 22.5 0.0 8.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain Nucleoporin2 PF04096.9 KOS21269.1 - 0.086 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Nucleoporin autopeptidase TruD PF01142.13 KOS21270.1 - 9.1e-47 159.5 0.0 5.6e-43 147.0 0.0 3.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) MarR_2 PF12802.2 KOS21270.1 - 0.036 13.7 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 MarR family DUF4232 PF14016.1 KOS21270.1 - 0.57 9.8 2.7 1.8 8.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) Ribosomal_L7Ae PF01248.21 KOS21271.1 - 8.6e-30 102.1 1.1 1.1e-29 101.7 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 KOS21271.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Rotamase_3 PF13616.1 KOS21272.1 - 1.5e-18 67.1 0.1 2.6e-18 66.3 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 KOS21272.1 - 3e-17 63.1 0.0 4.3e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KOS21272.1 - 3.4e-05 24.4 0.0 4.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Glyco_transf_90 PF05686.7 KOS21273.1 - 2.6e-11 42.8 8.4 5.7e-06 25.2 0.1 4.1 3 2 0 3 3 3 3 Glycosyl transferase family 90 Ribosomal_S8 PF00410.14 KOS21274.1 - 2.2e-25 88.9 0.0 3.1e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 MEF2_binding PF09047.5 KOS21275.1 - 0.11 12.2 0.4 0.32 10.6 0.3 1.8 1 0 0 1 1 1 0 MEF2 binding CK2S PF15011.1 KOS21275.1 - 0.12 12.1 2.4 0.15 11.8 0.1 2.1 2 0 0 2 2 2 0 Casein Kinase 2 substrate ING PF12998.2 KOS21275.1 - 1.2 9.4 6.4 0.4 10.9 0.3 2.8 2 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding ERp29 PF07749.7 KOS21275.1 - 2.1 9.0 11.0 5.3 7.7 0.0 4.1 4 0 0 4 4 4 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF3487 PF11990.3 KOS21275.1 - 5.3 6.4 5.6 12 5.3 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) Spectrin PF00435.16 KOS21275.1 - 6.7 7.0 12.2 0.2 11.9 1.5 3.0 3 1 0 3 3 3 0 Spectrin repeat FadA PF09403.5 KOS21276.1 - 0.086 12.8 0.3 0.57 10.2 0.0 2.5 3 1 0 3 3 3 0 Adhesion protein FadA Proteasome PF00227.21 KOS21277.1 - 2.1e-48 164.1 0.0 2.5e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KOS21277.1 - 0.00066 18.9 0.5 0.0013 18.0 0.4 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Asp PF00026.18 KOS21279.1 - 1.3e-55 188.8 0.1 2.3e-55 188.0 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KOS21279.1 - 5.3e-05 23.2 0.0 5.3e-05 23.2 0.0 2.5 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KOS21279.1 - 0.052 13.1 0.0 0.87 9.1 0.0 2.4 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Zn_clus PF00172.13 KOS21280.1 - 2.3e-07 30.5 6.9 4.4e-07 29.7 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4175 PF13779.1 KOS21280.1 - 1.3 6.6 8.4 1.7 6.2 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.8 KOS21280.1 - 1.5 8.6 9.8 1.8 8.3 6.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HAD_2 PF13419.1 KOS21281.1 - 3.4e-18 66.4 0.0 4.4e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KOS21281.1 - 6.2e-09 35.4 0.1 1.1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KOS21281.1 - 3.3e-06 27.6 0.3 3.8e-05 24.1 0.1 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 KOS21281.1 - 0.0015 18.2 0.0 0.047 13.3 0.0 2.2 1 1 1 2 2 2 1 NLI interacting factor-like phosphatase Nop16 PF09420.5 KOS21284.1 - 5.6e-46 156.6 6.9 9.5e-46 155.8 4.8 1.3 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 MARVEL PF01284.18 KOS21285.1 - 0.0072 16.1 13.2 0.017 14.9 9.2 1.6 1 1 0 1 1 1 1 Membrane-associating domain MFS_1 PF07690.11 KOS21286.1 - 1.3e-43 149.0 47.7 1.3e-43 149.0 33.0 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS21286.1 - 5.6e-17 61.4 32.2 3.8e-13 48.8 8.0 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MutL PF13941.1 KOS21286.1 - 0.00026 19.4 0.0 0.00041 18.8 0.0 1.1 1 0 0 1 1 1 1 MutL protein MFS_1_like PF12832.2 KOS21286.1 - 0.066 13.0 2.3 0.13 12.0 0.6 2.3 2 0 0 2 2 2 0 MFS_1 like family DHDPS PF00701.17 KOS21287.1 - 1.3e-35 122.4 0.0 1.6e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Antimicrobial_1 PF08018.6 KOS21287.1 - 0.082 12.8 0.2 0.26 11.2 0.1 1.9 1 0 0 1 1 1 0 Frog antimicrobial peptide DnaJ PF00226.26 KOS21288.1 - 1.1e-26 92.3 5.6 1.8e-26 91.6 3.9 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KOS21288.1 - 1.6e-21 75.9 4.0 3.7e-20 71.5 0.1 2.5 2 1 0 2 2 2 2 DnaJ C terminal domain AAA_16 PF13191.1 KOS21289.1 - 5.4e-06 26.5 0.1 5.4e-06 26.5 0.1 4.1 4 0 0 4 4 3 1 AAA ATPase domain NACHT PF05729.7 KOS21289.1 - 7.2e-06 25.7 0.1 2.3e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KOS21289.1 - 0.00032 20.8 0.2 0.0081 16.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KOS21289.1 - 0.00055 20.1 0.4 0.024 14.8 0.0 3.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SAPS PF04499.10 KOS21289.1 - 0.044 12.4 10.0 0.034 12.8 4.1 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 KOS21289.1 - 0.054 11.5 24.0 0.57 8.1 0.2 2.1 2 0 0 2 2 2 0 CDC45-like protein KAP_NTPase PF07693.9 KOS21289.1 - 0.1 11.5 0.0 0.1 11.5 0.0 2.8 2 1 1 3 3 2 0 KAP family P-loop domain Med15 PF09606.5 KOS21289.1 - 0.13 10.4 7.8 0.18 9.9 5.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Daxx PF03344.10 KOS21289.1 - 0.45 8.9 28.2 0.74 8.2 19.5 1.2 1 0 0 1 1 1 0 Daxx Family DHHW PF14286.1 KOS21289.1 - 0.55 9.4 11.1 0.96 8.6 7.7 1.3 1 0 0 1 1 1 0 DHHW protein Prog_receptor PF02161.10 KOS21289.1 - 0.67 8.7 8.1 1.1 7.9 5.6 1.3 1 0 0 1 1 1 0 Progesterone receptor RNA_pol_3_Rpc31 PF11705.3 KOS21289.1 - 0.81 9.5 26.8 1.5 8.6 18.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Serglycin PF04360.7 KOS21289.1 - 1 9.0 25.5 80 2.9 17.7 2.5 1 1 0 1 1 1 0 Serglycin Viral_helicase1 PF01443.13 KOS21289.1 - 1.3 8.5 0.0 1.3 8.5 0.0 2.8 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase Plasmodium_Vir PF05795.6 KOS21289.1 - 2.6 7.1 7.8 4.6 6.3 5.4 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF775 PF05603.7 KOS21289.1 - 2.9 7.3 8.3 5.9 6.3 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Ycf1 PF05758.7 KOS21289.1 - 4.4 4.8 19.4 0.0046 14.7 5.0 2.0 3 0 0 3 3 3 0 Ycf1 Trypan_PARP PF05887.6 KOS21289.1 - 6.4 6.5 24.0 11 5.7 16.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GSHPx PF00255.14 KOS21290.1 - 2.3e-36 123.4 0.0 2.9e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KOS21290.1 - 0.00053 19.6 0.2 0.001 18.7 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KOS21290.1 - 0.024 14.1 0.1 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 Redoxin DUF4174 PF13778.1 KOS21290.1 - 0.07 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) DAO PF01266.19 KOS21291.1 - 2.8e-55 187.6 5.9 4.5e-55 186.9 4.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KOS21291.1 - 0.0045 16.9 0.2 0.015 15.2 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.14 KOS21291.1 - 0.048 12.8 0.2 1.4 8.0 0.1 2.1 2 0 0 2 2 2 0 GMC oxidoreductase GDA1_CD39 PF01150.12 KOS21292.1 - 7e-99 331.2 0.0 8.5e-99 330.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Zip PF02535.17 KOS21293.1 - 0.068 12.1 1.0 0.094 11.7 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 KOS21293.1 - 8.6 5.6 10.8 12 5.1 7.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HGTP_anticodon2 PF12745.2 KOS21294.1 - 8e-72 241.6 0.3 8e-72 241.6 0.2 2.7 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 KOS21294.1 - 9.5e-70 234.6 0.0 1.1e-34 119.7 0.0 3.9 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KOS21294.1 - 7.1e-45 153.0 0.0 9.6e-20 70.7 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 KOS21294.1 - 6e-14 51.8 0.0 6e-14 51.8 0.0 3.4 4 1 0 4 4 4 1 Histidyl-tRNA synthetase RWD PF05773.17 KOS21294.1 - 3.6e-13 49.3 0.0 1.1e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 RWD domain APH PF01636.18 KOS21294.1 - 4.4e-06 26.6 2.4 0.095 12.4 0.0 3.2 3 0 0 3 3 3 2 Phosphotransferase enzyme family Init_tRNA_PT PF04179.7 KOS21295.1 - 2.8e-128 428.6 0.0 1.4e-127 426.3 0.0 1.8 1 1 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase GFO_IDH_MocA PF01408.17 KOS21295.1 - 4.6e-10 40.0 0.3 1.8e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Sec16_C PF12931.2 KOS21296.1 - 1e-92 310.9 0.0 1.3e-92 310.5 0.0 1.1 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KOS21296.1 - 2.7e-30 104.7 0.0 5e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Suc_Fer-like PF06999.7 KOS21297.1 - 6e-18 65.7 0.0 8.8e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Aa_trans PF01490.13 KOS21298.1 - 3e-83 279.6 30.4 3.5e-83 279.3 21.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4044 PF13253.1 KOS21298.1 - 4.4 6.5 7.8 1.8 7.7 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) E1-E2_ATPase PF00122.15 KOS21299.1 - 2.1e-16 59.6 0.0 5.5e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KOS21299.1 - 1e-15 58.7 0.0 3.2e-15 57.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KOS21299.1 - 8.4e-11 42.3 0.0 2.3e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS21299.1 - 0.00094 19.0 0.0 0.0033 17.3 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KOS21299.1 - 0.0018 17.9 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FAD_binding_6 PF00970.19 KOS21300.1 - 3.1e-05 23.9 0.0 0.00025 21.1 0.0 2.1 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KOS21300.1 - 8.2e-05 23.1 0.0 0.00021 21.8 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KOS21300.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Acyl-CoA_dh_1 PF00441.19 KOS21301.1 - 3.7e-27 95.2 1.3 6.1e-27 94.5 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KOS21301.1 - 7.5e-15 54.1 0.0 1.6e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KOS21301.1 - 2e-14 54.1 0.1 4.8e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KOS21301.1 - 1e-11 45.1 1.6 1.9e-11 44.3 1.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ras PF00071.17 KOS21302.1 - 1e-56 190.8 0.0 1.2e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS21302.1 - 1.9e-18 67.0 0.0 2.8e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS21302.1 - 3.7e-13 49.0 0.0 4.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KOS21302.1 - 1.5e-07 31.3 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KOS21302.1 - 1.7e-07 30.6 0.0 2.1e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KOS21302.1 - 3.3e-07 29.9 0.0 6.4e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KOS21302.1 - 0.00065 19.8 0.0 0.0011 19.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KOS21302.1 - 0.0011 18.2 0.1 0.0019 17.4 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KOS21302.1 - 0.0017 18.3 0.0 0.01 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KOS21302.1 - 0.002 17.8 0.0 0.0065 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SRPRB PF09439.5 KOS21302.1 - 0.0025 17.0 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 KOS21302.1 - 0.004 16.7 0.2 0.0082 15.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KOS21302.1 - 0.0046 16.6 0.2 0.0097 15.6 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase PduV-EutP PF10662.4 KOS21302.1 - 0.0047 16.4 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KOS21302.1 - 0.0063 16.0 0.2 0.31 10.5 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 KOS21302.1 - 0.0074 15.7 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain Septin PF00735.13 KOS21302.1 - 0.015 14.2 0.0 0.032 13.2 0.0 1.6 1 0 0 1 1 1 0 Septin NTPase_1 PF03266.10 KOS21302.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 NTPase MobB PF03205.9 KOS21302.1 - 0.022 14.4 0.1 0.056 13.1 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 KOS21302.1 - 0.029 13.8 0.0 0.066 12.6 0.0 1.6 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KOS21302.1 - 0.066 13.3 0.0 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 KOS21302.1 - 0.079 11.7 0.2 0.35 9.6 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 KOS21302.1 - 0.088 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Spo12 PF05032.7 KOS21303.1 - 1.4e-09 37.4 2.8 2e-09 36.9 1.0 2.0 2 0 0 2 2 2 1 Spo12 family DUF2264 PF10022.4 KOS21304.1 - 2.7e-113 378.3 0.8 4.7e-113 377.5 0.5 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) ASXH PF13919.1 KOS21305.1 - 2.1e-22 79.3 0.0 2.5e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Asx homology domain Bclx_interact PF08945.5 KOS21305.1 - 0.12 11.9 0.2 0.25 10.9 0.2 1.4 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain Paf1 PF03985.8 KOS21306.1 - 2.6e-52 178.0 0.2 6.1e-52 176.8 0.2 1.5 1 1 0 1 1 1 1 Paf1 Rer1 PF03248.8 KOS21307.1 - 2.2e-79 265.1 9.9 2.5e-79 264.9 6.9 1.0 1 0 0 1 1 1 1 Rer1 family NAD_binding_10 PF13460.1 KOS21308.1 - 2.9e-13 50.2 0.0 1.9e-11 44.3 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KOS21308.1 - 5.9e-08 32.4 0.0 1.8e-07 30.8 0.0 1.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KOS21308.1 - 7.6e-05 21.5 0.0 0.00043 19.0 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KOS21308.1 - 8.8e-05 22.4 0.0 0.00096 19.1 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KOS21308.1 - 0.017 14.0 0.0 0.3 9.9 0.0 2.5 2 1 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.7 KOS21308.1 - 0.025 13.4 0.0 10 4.9 0.0 3.0 2 2 1 3 3 3 0 Male sterility protein SYF2 PF08231.7 KOS21309.1 - 6.5e-52 175.7 17.2 6.5e-52 175.7 11.9 1.8 2 0 0 2 2 2 1 SYF2 splicing factor DUF2404 PF10296.4 KOS21310.1 - 4.6e-06 26.6 0.0 2.5e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) YEATS PF03366.11 KOS21311.1 - 3.2e-28 97.2 0.2 4.7e-28 96.7 0.1 1.2 1 0 0 1 1 1 1 YEATS family DUF4279 PF14106.1 KOS21311.1 - 0.088 12.6 0.1 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) Ribosomal_60s PF00428.14 KOS21311.1 - 8 6.9 13.4 1.8 8.9 6.0 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Nucleoside_tran PF01733.13 KOS21312.1 - 2.2e-24 86.1 25.4 3.6e-14 52.6 0.7 4.6 4 1 1 5 5 5 3 Nucleoside transporter MFS_1 PF07690.11 KOS21312.1 - 0.089 11.4 48.8 0.031 12.9 4.9 2.4 1 1 1 2 2 2 0 Major Facilitator Superfamily Ins_P5_2-kin PF06090.7 KOS21313.1 - 1.4e-35 122.8 0.0 2.9e-35 121.8 0.0 1.5 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase HET PF06985.6 KOS21314.1 - 2.9e-19 69.6 0.1 7.6e-19 68.2 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Catalase PF00199.14 KOS21315.1 - 5e-160 532.3 0.3 6.7e-160 531.9 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KOS21315.1 - 2.9e-20 71.8 0.2 5.7e-20 70.9 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Dynactin_p62 PF05502.8 KOS21316.1 - 0.041 12.6 1.2 0.058 12.1 0.5 1.4 1 1 0 1 1 1 0 Dynactin p62 family Mo-co_dimer PF03404.11 KOS21318.1 - 2.6e-08 33.5 0.4 2.6e-08 33.5 0.3 1.3 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Type_III_YscX PF09474.5 KOS21318.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) Oxidored_molyb PF00174.14 KOS21319.1 - 2.4e-37 127.9 0.0 1.3e-36 125.5 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase molybdopterin binding domain SLBB PF10531.4 KOS21319.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 SLBB domain HAD_2 PF13419.1 KOS21320.1 - 2.6e-19 70.0 0.2 1.6e-18 67.5 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KOS21320.1 - 0.0019 17.8 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2608 PF11019.3 KOS21320.1 - 0.032 13.2 0.0 5 6.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2608) Chromo PF00385.19 KOS21321.1 - 2.3e-14 52.8 7.3 3.8e-09 36.0 0.0 2.8 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF566 PF04484.7 KOS21321.1 - 0.084 12.3 3.2 0.049 13.1 1.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF566) HSP90 PF00183.13 KOS21321.1 - 1.7 6.9 13.2 2.4 6.4 9.1 1.1 1 0 0 1 1 1 0 Hsp90 protein Lipase_3 PF01764.20 KOS21322.1 - 1.6e-25 89.3 0.0 3e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) FliL PF03748.9 KOS21322.1 - 0.098 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL MMR_HSR1 PF01926.18 KOS21323.1 - 4.4e-08 33.0 0.0 1.4e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KOS21323.1 - 3.1e-06 26.4 0.1 7.5e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KOS21323.1 - 7.6e-05 22.5 3.6 0.012 15.3 0.1 3.4 2 2 0 2 2 2 1 Dynamin family AIG1 PF04548.11 KOS21323.1 - 0.0098 15.0 0.1 4.6 6.2 0.0 3.2 3 0 0 3 3 3 2 AIG1 family AAA_29 PF13555.1 KOS21323.1 - 0.066 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KOS21323.1 - 0.15 12.8 3.3 0.9 10.3 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KOS21323.1 - 3.8 7.7 12.1 1e+03 -0.2 8.4 2.7 1 1 0 1 1 1 0 AAA domain CAP59_mtransfer PF11735.3 KOS21324.1 - 4.8e-46 156.9 0.0 6e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Acetyltransf_1 PF00583.19 KOS21325.1 - 0.024 14.6 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 KOS21325.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase EII-Sor PF03609.9 KOS21327.1 - 0.05 12.8 0.3 0.078 12.2 0.2 1.4 1 0 0 1 1 1 0 PTS system sorbose-specific iic component Aminotran_5 PF00266.14 KOS21328.1 - 1.7e-31 109.2 0.0 2.9e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Lysine_decarbox PF03641.9 KOS21329.1 - 7.1e-30 103.5 0.1 1e-29 103.0 0.1 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase CLPTM1 PF05602.7 KOS21330.1 - 3.2e-151 503.9 0.0 4.3e-151 503.5 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Longin PF13774.1 KOS21332.1 - 2.9e-24 84.4 0.1 4.6e-24 83.7 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KOS21332.1 - 1.3e-15 56.7 0.0 4.1e-15 55.1 0.0 1.7 2 0 0 2 2 2 1 Synaptobrevin DUF1664 PF07889.7 KOS21332.1 - 0.0055 16.4 0.1 0.076 12.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) DUF4132 PF13569.1 KOS21332.1 - 0.061 12.8 0.3 9.6 5.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4132) DUF2077 PF09850.4 KOS21332.1 - 0.29 10.5 2.3 0.26 10.6 0.3 1.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) Sirohm_synth_C PF14823.1 KOS21332.1 - 7.1 6.0 5.8 10 5.5 0.6 2.8 2 1 1 3 3 3 0 Sirohaem biosynthesis protein C-terminal Elong_Iki1 PF10483.4 KOS21333.1 - 2.4e-81 273.1 0.0 2.8e-81 272.9 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 TrmE_N PF10396.4 KOS21334.1 - 2.4e-33 114.4 0.0 7.9e-33 112.8 0.0 1.9 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 KOS21334.1 - 5.6e-19 68.3 0.1 1.9e-18 66.6 0.0 2.0 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 KOS21334.1 - 3.3e-16 59.2 0.0 5.3e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS21334.1 - 9.5e-05 21.7 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KOS21334.1 - 9.5e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 KOS21334.1 - 0.021 15.3 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 KOS21334.1 - 0.029 14.6 0.1 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 KOS21334.1 - 0.17 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 UQ_con PF00179.21 KOS21335.1 - 1.8e-32 111.6 0.0 2.4e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KOS21335.1 - 0.008 16.0 0.0 0.016 15.0 0.0 1.6 1 1 0 1 1 1 1 RWD domain Cut12 PF11500.3 KOS21336.1 - 2.9e-38 130.9 10.2 2.9e-38 130.9 7.1 2.6 2 1 1 3 3 3 1 Spindle pole body formation-associated protein Phage_Integr_2 PF13009.1 KOS21336.1 - 0.29 10.0 5.1 0.46 9.3 3.5 1.3 1 0 0 1 1 1 0 Putative phage integrase Pox_A_type_inc PF04508.7 KOS21336.1 - 2.4 8.1 18.5 1.2 9.1 0.2 5.8 5 1 1 6 6 6 0 Viral A-type inclusion protein repeat CENP-B_dimeris PF09026.5 KOS21336.1 - 5.4 7.3 12.7 0.82 9.9 0.7 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2796 PF10986.3 KOS21336.1 - 9.8 6.1 10.2 3.7 7.4 3.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) UreF PF01730.11 KOS21337.1 - 3.5e-13 49.8 8.0 1.8e-12 47.6 5.6 2.0 1 1 0 1 1 1 1 UreF DUF429 PF04250.8 KOS21337.1 - 0.017 14.3 0.1 0.03 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF429) RRM_1 PF00076.17 KOS21338.1 - 4.5e-09 35.8 0.2 1.4e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS21338.1 - 1.5e-06 27.9 1.0 3.1e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS21338.1 - 6e-05 22.9 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KOS21338.1 - 0.00014 21.5 0.0 0.0003 20.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MoeA_C PF03454.10 KOS21338.1 - 0.0014 18.4 0.1 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) zf-CCCH PF00642.19 KOS21338.1 - 0.0094 15.6 0.2 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TGS PF02824.16 KOS21339.1 - 1.3e-20 72.9 0.0 2.3e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KOS21339.1 - 3.1e-19 69.0 0.1 1e-18 67.3 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS21339.1 - 9.1e-13 47.7 0.0 1.4e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KOS21339.1 - 9.1e-05 22.3 0.3 0.034 13.9 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KOS21339.1 - 0.0023 18.4 0.0 0.0063 17.0 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein ArgK PF03308.11 KOS21339.1 - 0.057 12.1 0.1 0.12 11.0 0.1 1.6 1 0 0 1 1 1 0 ArgK protein cobW PF02492.14 KOS21340.1 - 2.5e-37 128.0 0.0 1e-36 126.0 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KOS21340.1 - 0.00047 19.8 0.0 0.0017 18.0 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KOS21340.1 - 0.0033 17.1 0.0 0.0097 15.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Suf PF05843.9 KOS21340.1 - 0.0056 16.4 0.8 0.008 15.9 0.5 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Viral_helicase1 PF01443.13 KOS21340.1 - 0.0087 15.6 0.2 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 KOS21340.1 - 0.014 14.8 0.1 0.055 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 KOS21340.1 - 0.026 14.5 1.9 0.031 14.2 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain Spt20 PF12090.3 KOS21340.1 - 0.034 13.5 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Spt20 family AAA_14 PF13173.1 KOS21340.1 - 0.056 13.3 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain CobW_C PF07683.9 KOS21340.1 - 0.059 13.0 0.0 0.56 9.9 0.0 2.5 2 1 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain Alg14 PF08660.6 KOS21340.1 - 0.077 12.9 0.2 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like AAA_22 PF13401.1 KOS21340.1 - 0.089 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF463 PF04317.7 KOS21340.1 - 0.096 11.2 0.0 0.096 11.2 0.0 1.5 2 0 0 2 2 2 0 YcjX-like family, DUF463 NTPase_1 PF03266.10 KOS21340.1 - 0.097 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.1 KOS21340.1 - 0.28 10.7 4.5 3 7.3 3.1 2.0 1 1 0 1 1 1 0 AAA domain PUL PF08324.6 KOS21341.1 - 1.8e-35 122.0 0.0 2.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 KOS21341.1 - 8.2e-34 116.5 0.0 1.4e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 KOS21341.1 - 6.1e-13 48.3 0.0 1.3e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KOS21341.1 - 0.00016 21.8 0.0 0.0006 19.9 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KOS21341.1 - 0.0022 17.6 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.1 KOS21341.1 - 0.0071 16.1 0.0 0.047 13.5 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain T4_deiodinase PF00837.12 KOS21341.1 - 0.027 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Iodothyronine deiodinase Redoxin PF08534.5 KOS21341.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Redoxin TraF PF13728.1 KOS21341.1 - 0.19 11.1 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein SspB PF04386.8 KOS21342.1 - 0.74 9.4 11.2 0.51 9.9 5.7 1.9 2 0 0 2 2 2 0 Stringent starvation protein B DUF4611 PF15387.1 KOS21343.1 - 0.032 14.3 0.5 0.06 13.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) eIF-3c_N PF05470.7 KOS21344.1 - 0.91 7.5 4.8 1.2 7.1 3.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Hus1 PF04005.7 KOS21345.1 - 4.7e-92 308.0 0.0 5.3e-92 307.8 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Glyco_hydro_63 PF03200.11 KOS21346.1 - 7.7e-227 754.9 0.0 8.5e-226 751.5 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 KOS21346.1 - 1e-07 30.9 0.0 1.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Trehalase Ank_2 PF12796.2 KOS21347.1 - 1.9e-17 63.3 0.0 5.6e-08 33.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KOS21347.1 - 1.2e-16 59.6 0.0 1.6e-06 27.6 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KOS21347.1 - 3.9e-13 49.5 0.3 9.2e-07 29.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS21347.1 - 2.4e-11 42.6 0.0 0.0016 18.4 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KOS21347.1 - 9.7e-11 41.5 0.3 8.6e-05 22.6 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Filaggrin PF03516.8 KOS21347.1 - 6.9 7.2 8.5 2 8.9 0.4 3.7 4 0 0 4 4 4 0 Filaggrin FH2 PF02181.18 KOS21348.1 - 6.8e-82 275.2 3.7 6.8e-82 275.2 2.6 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 KOS21348.1 - 5.1e-60 202.0 0.1 5.1e-60 202.0 0.0 3.1 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KOS21348.1 - 2.4e-50 170.7 0.6 2.4e-50 170.7 0.4 3.2 3 1 1 4 4 4 1 Diaphanous FH3 Domain DUF1777 PF08648.7 KOS21349.1 - 7.6e-29 100.7 89.4 6.2e-28 97.7 23.3 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF1777) Vps55 PF04133.9 KOS21352.1 - 4.8e-45 152.1 6.8 5.3e-45 152.0 4.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 GtrA PF04138.9 KOS21352.1 - 0.13 12.2 3.7 0.19 11.7 2.6 1.3 1 1 0 1 1 1 0 GtrA-like protein Ribosomal_L28e PF01778.12 KOS21353.1 - 4.8e-34 117.2 0.8 4.8e-34 117.2 0.6 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 KOS21353.1 - 6.2e-20 71.1 29.1 6.2e-20 71.1 20.2 3.5 1 1 1 2 2 2 1 Mak16 protein C-terminal region Reovirus_cap PF00979.12 KOS21353.1 - 0.013 14.5 0.1 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 PYC_OADA PF02436.13 KOS21353.1 - 0.25 10.7 1.3 0.38 10.1 0.4 1.7 1 1 0 1 1 1 0 Conserved carboxylase domain Nop14 PF04147.7 KOS21353.1 - 0.54 8.1 41.4 0.73 7.6 28.7 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 KOS21353.1 - 1 7.6 36.7 1.5 7.0 25.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mso1_Sec1_bdg PF14475.1 KOS21354.1 - 4.6e-18 64.3 0.1 8.5e-18 63.4 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 RabGAP-TBC PF00566.13 KOS21355.1 - 1.1e-35 123.0 0.2 1.8e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 KOS21355.1 - 1.9e-08 33.8 0.0 0.00025 20.3 0.0 3.6 4 0 0 4 4 4 3 Domain of unknown function (DUF3548) Sugar_tr PF00083.19 KOS21356.1 - 9.7e-85 284.8 36.2 1.2e-44 152.6 6.6 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 KOS21356.1 - 9.3e-16 57.4 30.0 3.7e-15 55.4 19.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.1 KOS21357.1 - 1.1e-07 31.8 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KOS21357.1 - 1.2e-05 25.2 0.0 3.1e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 KOS21357.1 - 0.0018 17.4 0.1 0.003 16.7 0.1 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Pex14_N PF04695.8 KOS21357.1 - 0.095 12.7 6.5 0.023 14.7 2.2 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 KOS21357.1 - 5.2 6.3 16.0 7.4 5.8 11.1 1.2 1 0 0 1 1 1 0 Vta1 like TRAPPC9-Trs120 PF08626.6 KOS21358.1 - 6.2e-124 414.7 0.0 1e-115 387.4 0.0 2.1 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF3973 PF13119.1 KOS21358.1 - 0.3 11.0 0.0 0.84 9.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) Chorismate_bind PF00425.13 KOS21359.1 - 5.3e-60 202.9 0.0 3.3e-33 115.1 0.0 3.8 3 1 0 3 3 3 3 chorismate binding enzyme GATase PF00117.23 KOS21359.1 - 2.7e-23 82.4 0.0 1.9e-22 79.6 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KOS21359.1 - 1.4e-11 44.6 0.0 3e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KOS21359.1 - 1.2e-05 24.9 0.0 2.7e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase C26 PAP2_3 PF14378.1 KOS21360.1 - 1.3e-22 80.3 10.0 1e-17 64.2 2.4 3.0 2 1 0 2 2 2 2 PAP2 superfamily PAP2 PF01569.16 KOS21360.1 - 5.2 6.7 13.9 0.061 13.0 3.5 2.2 2 1 1 3 3 3 0 PAP2 superfamily MFS_1 PF07690.11 KOS21363.1 - 7.6e-34 116.9 37.4 4.9e-29 101.1 15.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PBAN PF05874.6 KOS21364.1 - 0.03 13.6 1.0 0.057 12.7 0.7 1.4 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) SLX9 PF15341.1 KOS21364.1 - 1.4 9.3 6.3 0.96 9.8 1.5 2.5 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 GTP_cyclohydroI PF01227.17 KOS21365.1 - 7e-73 243.7 0.2 9.7e-73 243.2 0.2 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KOS21365.1 - 0.0017 18.2 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein TFIIA PF03153.8 KOS21365.1 - 0.88 9.4 8.1 1.2 8.9 5.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2489 PF10675.4 KOS21365.1 - 0.95 9.1 0.0 0.95 9.1 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2489) PhoD PF09423.5 KOS21367.1 - 1.1e-05 24.2 0.0 2.2e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 PhoD-like phosphatase Metallophos PF00149.23 KOS21368.1 - 1.2e-12 47.6 0.7 7.2e-08 32.0 0.1 2.7 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase APC_CDC26 PF10471.4 KOS21369.1 - 3.1e-14 53.4 8.3 3.9e-14 53.1 5.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Phage_B PF02304.10 KOS21369.1 - 0.14 12.4 5.2 0.16 12.2 3.6 1.1 1 0 0 1 1 1 0 Scaffold protein B DUF1983 PF09327.6 KOS21369.1 - 0.15 12.0 4.1 0.2 11.6 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1983) Med3 PF11593.3 KOS21369.1 - 0.35 10.0 5.1 0.34 10.1 3.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_60s PF00428.14 KOS21369.1 - 1.4 9.3 8.2 1.8 8.9 5.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Hepcidin PF06446.7 KOS21369.1 - 2.5 8.5 6.1 6 7.3 1.9 2.0 2 0 0 2 2 2 0 Hepcidin DUF4557 PF15101.1 KOS21369.1 - 3.2 7.5 5.2 3.4 7.4 3.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Homeobox_KN PF05920.6 KOS21370.1 - 5.8e-13 48.3 1.9 5.8e-13 48.3 1.3 2.2 3 0 0 3 3 3 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.11 KOS21370.1 - 9.7e-07 28.5 0.8 2.1e-05 24.2 0.1 3.1 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain Homeobox PF00046.24 KOS21370.1 - 6.4e-05 22.4 0.3 0.00019 20.9 0.2 1.8 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 KOS21370.1 - 0.0052 17.0 22.2 0.009 16.2 2.9 4.7 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KOS21370.1 - 0.021 15.1 3.7 0.021 15.1 2.6 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type HA PF03457.9 KOS21370.1 - 0.036 14.1 3.8 0.09 12.8 0.4 3.3 3 0 0 3 3 3 0 Helicase associated domain BIR PF00653.16 KOS21370.1 - 9.4 6.7 10.4 1.6 9.1 0.3 3.2 1 1 2 3 3 3 0 Inhibitor of Apoptosis domain HTH_Tnp_Tc5 PF03221.11 KOS21371.1 - 8.6e-06 25.4 0.2 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 Tc5 transposase DNA-binding domain Ponericin PF07442.6 KOS21371.1 - 0.58 10.0 0.0 0.58 10.0 0.0 2.9 3 1 1 4 4 4 0 Ponericin Zip PF02535.17 KOS21372.1 - 2.2e-56 191.2 4.0 8.1e-56 189.3 2.7 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Glyco_hydro_17 PF00332.13 KOS21373.1 - 7.2e-05 21.9 0.1 0.00016 20.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.8 KOS21373.1 - 0.025 13.3 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 RRM_1 PF00076.17 KOS21374.1 - 6.2e-30 102.6 0.2 4.3e-14 51.8 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS21374.1 - 2e-24 85.3 0.0 2.4e-12 46.6 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS21374.1 - 4.7e-10 39.1 0.0 0.0013 18.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KOS21374.1 - 0.041 13.6 0.2 4 7.2 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 ETF PF01012.16 KOS21375.1 - 2.2e-36 125.0 0.9 2.8e-36 124.7 0.6 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Hamartin PF04388.7 KOS21376.1 - 8.1e-45 153.6 15.0 8.1e-45 153.6 10.4 2.4 1 1 0 2 2 2 1 Hamartin protein DUF4066 PF13278.1 KOS21377.1 - 4.2e-23 81.4 0.0 2.5e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 KOS21377.1 - 0.00083 18.8 0.0 0.0032 16.9 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family MFS_1 PF07690.11 KOS21378.1 - 2.1e-33 115.4 39.1 2.1e-33 115.4 27.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Npa1 PF11707.3 KOS21379.1 - 3.6e-76 256.2 0.0 5.2e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal DDHD PF02862.12 KOS21379.1 - 0.37 10.5 1.6 0.64 9.7 1.1 1.3 1 0 0 1 1 1 0 DDHD domain Prothymosin PF03247.9 KOS21379.1 - 0.91 9.7 21.0 1.9 8.6 14.5 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family RNA_pol_3_Rpc31 PF11705.3 KOS21379.1 - 1.5 8.7 12.4 2.8 7.8 8.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Daxx PF03344.10 KOS21379.1 - 3.9 5.8 13.3 5.7 5.3 9.3 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KOS21379.1 - 3.9 5.3 6.4 5.7 4.8 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KOS21379.1 - 4.2 5.1 12.6 8.3 4.1 8.7 1.4 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 KOS21379.1 - 6.3 5.9 6.2 9.8 5.3 4.3 1.2 1 0 0 1 1 1 0 NOA36 protein His_Phos_2 PF00328.17 KOS21380.1 - 1.1e-51 176.2 0.0 1.3e-51 175.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Fungal_trans PF04082.13 KOS21381.1 - 6.3e-24 84.2 0.2 9.2e-24 83.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3046 PF11248.3 KOS21381.1 - 0.16 11.9 1.1 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) Mito_fiss_reg PF05308.6 KOS21381.1 - 0.18 11.1 0.9 0.32 10.3 0.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF1090 PF06476.7 KOS21382.1 - 0.014 15.0 2.3 0.014 15.0 1.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) FANCI_S3 PF14677.1 KOS21382.1 - 0.19 11.0 1.2 0.95 8.7 0.1 1.9 2 0 0 2 2 2 0 FANCI solenoid 3 LRR_9 PF14580.1 KOS21383.1 - 1.7e-43 148.1 0.0 3.6e-43 147.1 0.0 1.6 1 0 0 1 1 1 1 Leucine-rich repeat Pkinase PF00069.20 KOS21383.1 - 3.1e-24 85.5 0.0 4.6e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KOS21383.1 - 1.6e-11 43.5 16.4 1.5e-07 31.0 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.17 KOS21383.1 - 6.3e-10 38.2 6.2 0.045 13.8 0.1 6.8 6 0 0 6 6 6 2 HEAT repeat LRR_4 PF12799.2 KOS21383.1 - 3.1e-07 29.8 1.6 0.00033 20.1 0.1 3.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS21383.1 - 3.6e-06 26.6 1.5 1e-05 25.1 0.2 2.5 2 0 0 2 2 2 1 Leucine rich repeat HEAT_2 PF13646.1 KOS21383.1 - 1.1e-05 25.5 1.2 0.043 14.1 0.0 4.2 1 1 2 3 3 3 2 HEAT repeats Pkinase_Tyr PF07714.12 KOS21383.1 - 0.00039 19.5 0.0 0.00061 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 KOS21383.1 - 0.022 15.2 7.6 1.3 9.5 0.4 4.8 5 0 0 5 5 4 0 HEAT-like repeat LRR_7 PF13504.1 KOS21383.1 - 0.039 14.1 2.3 2.4 8.7 0.1 4.0 4 0 0 4 4 2 0 Leucine rich repeat Kinase-like PF14531.1 KOS21383.1 - 0.15 10.9 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Nucleoporin_N PF08801.6 KOS21383.1 - 0.26 9.9 0.0 4.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like MSP1_C PF07462.6 KOS21383.1 - 0.34 9.2 0.2 0.54 8.5 0.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CBFD_NFYB_HMF PF00808.18 KOS21384.1 - 1.5e-10 40.9 0.1 0.00024 21.1 0.0 2.5 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TatD_DNase PF01026.16 KOS21386.1 - 6.8e-25 87.7 0.0 1.8e-24 86.3 0.0 1.7 1 1 0 1 1 1 1 TatD related DNase CDI PF02234.14 KOS21387.1 - 0.025 14.3 0.2 0.05 13.4 0.1 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Pyridox_oxase_2 PF12766.2 KOS21388.1 - 2.9e-19 69.2 0.0 8.4e-19 67.7 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Fis1_TPR_C PF14853.1 KOS21389.1 - 8.1e-25 86.4 1.7 1.3e-24 85.8 1.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KOS21389.1 - 3e-18 64.8 0.2 5.5e-18 63.9 0.0 1.6 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 KOS21389.1 - 0.0046 16.7 2.2 0.0096 15.7 1.5 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 KOS21389.1 - 0.0052 17.4 0.2 0.0099 16.5 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Spc24 PF08286.6 KOS21390.1 - 6.9e-41 138.6 1.3 6.9e-39 132.2 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 IncA PF04156.9 KOS21390.1 - 0.032 13.8 6.0 0.049 13.2 4.2 1.2 1 0 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 KOS21390.1 - 0.049 12.8 2.0 0.062 12.4 1.4 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Retrotrans_gag PF03732.12 KOS21390.1 - 0.09 12.8 0.9 0.22 11.6 0.6 1.8 1 1 0 1 1 1 0 Retrotransposon gag protein Vps5 PF09325.5 KOS21390.1 - 0.12 11.6 5.7 0.19 10.9 4.0 1.4 1 1 0 1 1 1 0 Vps5 C terminal like EAP30 PF04157.11 KOS21390.1 - 0.12 11.5 8.7 0.11 11.5 2.7 2.0 1 1 1 2 2 2 0 EAP30/Vps36 family Troponin PF00992.15 KOS21390.1 - 0.13 12.3 4.3 0.18 11.8 3.0 1.2 1 0 0 1 1 1 0 Troponin Laminin_II PF06009.7 KOS21390.1 - 0.18 11.5 6.0 0.53 10.0 4.2 1.7 1 1 0 1 1 1 0 Laminin Domain II PKI PF02827.11 KOS21390.1 - 0.2 11.8 3.4 0.42 10.7 0.2 2.4 1 1 1 2 2 2 0 cAMP-dependent protein kinase inhibitor Nsp1_C PF05064.8 KOS21390.1 - 0.26 10.9 3.2 0.97 9.0 0.2 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF4164 PF13747.1 KOS21390.1 - 0.37 10.9 11.7 0.53 10.4 6.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF3073 PF11273.3 KOS21390.1 - 0.57 10.7 4.4 0.56 10.7 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3073) FUSC PF04632.7 KOS21390.1 - 0.62 8.4 4.8 0.64 8.3 3.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin PF00804.20 KOS21390.1 - 0.7 10.0 4.5 0.98 9.6 2.8 1.5 1 1 0 1 1 1 0 Syntaxin APG6 PF04111.7 KOS21390.1 - 0.94 8.4 4.3 1.3 7.9 3.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Adeno_PIX PF03955.9 KOS21390.1 - 4.5 7.8 5.7 2.1 8.8 0.4 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) La PF05383.12 KOS21391.1 - 1.9e-11 43.5 0.0 2.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KOS21391.1 - 9.8e-09 34.7 0.6 2.4e-08 33.4 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS21391.1 - 6.4e-08 32.4 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS21391.1 - 2.1e-05 24.2 0.0 5.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC50 PF03381.10 KOS21392.1 - 3.9e-98 328.0 0.0 4.8e-98 327.7 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family GxDLY PF14607.1 KOS21392.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type CMD PF02627.15 KOS21393.1 - 1.4e-06 28.0 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family SPT16 PF08644.6 KOS21394.1 - 1.2e-56 190.7 0.2 1.2e-56 190.7 0.1 2.4 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KOS21394.1 - 5.2e-43 146.3 4.9 1.5e-42 144.8 1.2 3.1 2 1 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 KOS21394.1 - 5.3e-23 81.6 0.0 9.1e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 KOS21394.1 - 2.9e-22 78.4 0.2 1e-21 76.6 0.1 2.1 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DWNN PF08783.6 KOS21395.1 - 2.7e-29 100.8 0.0 4.8e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 KOS21395.1 - 0.0011 18.4 5.8 0.0017 17.7 3.1 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 KOS21395.1 - 0.024 14.5 1.9 0.057 13.3 1.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-RING_6 PF14835.1 KOS21395.1 - 0.037 13.7 1.3 0.069 12.9 0.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE_2 PF02318.11 KOS21395.1 - 0.09 12.6 1.7 0.26 11.2 1.1 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_4 PF14570.1 KOS21395.1 - 0.23 11.0 6.5 0.5 9.9 4.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KOS21395.1 - 1.6 8.3 6.4 3.4 7.2 4.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 KOS21395.1 - 1.7 8.3 9.5 3.3 7.4 6.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS21395.1 - 3.3 7.5 13.7 0.26 11.0 5.6 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KOS21395.1 - 3.4 7.7 14.7 0.27 11.2 6.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS21395.1 - 5.4 6.9 12.7 0.089 12.6 4.0 1.6 2 0 0 2 2 2 0 Ring finger domain Peptidase_M20 PF01546.23 KOS21396.1 - 2.3e-32 112.0 0.0 4.5e-32 111.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KOS21396.1 - 1.4e-12 47.3 0.0 2.2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Transthyretin PF00576.16 KOS21397.1 - 1.9e-23 82.4 0.2 4.7e-20 71.5 0.2 2.9 1 1 0 1 1 1 1 HIUase/Transthyretin family ArsA_ATPase PF02374.10 KOS21398.1 - 7.7e-110 366.7 0.0 8.8e-110 366.5 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KOS21398.1 - 4.3e-16 58.8 0.3 1.1e-15 57.5 0.2 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KOS21398.1 - 1.7e-08 34.5 0.0 1.2e-07 31.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 KOS21398.1 - 4.7e-06 25.9 0.0 9.9e-06 24.9 0.0 1.5 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KOS21398.1 - 6e-05 22.5 0.0 0.0021 17.5 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KOS21398.1 - 0.0037 16.9 0.0 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain YhjQ PF06564.7 KOS21398.1 - 0.0083 15.5 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 YhjQ protein AAA_25 PF13481.1 KOS21398.1 - 0.01 15.2 0.1 0.024 14.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KOS21398.1 - 0.014 14.8 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein MipZ PF09140.6 KOS21398.1 - 0.024 13.7 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ AAA_18 PF13238.1 KOS21398.1 - 0.054 13.8 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KOS21398.1 - 0.057 12.2 0.0 0.091 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 KOS21398.1 - 0.066 12.6 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Amidohydro_2 PF04909.9 KOS21399.1 - 1.8e-09 37.5 0.0 3.1e-09 36.8 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KOS21399.1 - 1.4e-06 28.6 0.1 1.6e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase PAF-AH_p_II PF03403.8 KOS21400.1 - 3.9e-17 61.5 0.1 7.1e-10 37.7 0.0 2.4 3 0 0 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KOS21400.1 - 9.7e-15 54.5 0.1 1.5e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS21400.1 - 4.1e-08 33.3 0.7 6e-08 32.8 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KOS21400.1 - 2.1e-05 23.5 0.0 5.1e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KOS21400.1 - 0.00055 18.8 0.1 0.017 13.9 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase Peptidase_S9 PF00326.16 KOS21400.1 - 0.0035 16.5 0.7 0.011 14.9 0.2 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family 2OG-FeII_Oxy PF03171.15 KOS21401.1 - 0.012 15.8 0.0 0.026 14.8 0.0 1.5 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Ribosomal_60s PF00428.14 KOS21401.1 - 0.57 10.6 4.4 3.8 7.9 0.1 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein p450 PF00067.17 KOS21402.1 - 6.7e-15 54.5 0.0 1.1e-14 53.8 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 WD40 PF00400.27 KOS21403.1 - 2e-13 49.6 6.6 1.7e-05 24.5 0.3 4.7 4 1 0 4 4 4 3 WD domain, G-beta repeat CENP-N PF05238.8 KOS21403.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like PQQ_3 PF13570.1 KOS21403.1 - 0.2 11.9 2.2 10 6.5 0.2 3.5 4 0 0 4 4 4 0 PQQ-like domain FRG1 PF06229.7 KOS21404.1 - 2.2e-47 161.0 0.3 6.3e-47 159.5 0.2 1.7 1 1 0 1 1 1 1 FRG1-like family Fascin PF06268.8 KOS21404.1 - 0.0068 16.4 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 Fascin domain F-box-like PF12937.2 KOS21405.1 - 2e-11 43.4 0.1 4.7e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS21405.1 - 0.00029 20.3 0.0 0.0007 19.1 0.0 1.7 1 1 0 1 1 1 1 F-box domain TPR_11 PF13414.1 KOS21405.1 - 0.012 15.1 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 KOS21405.1 - 0.13 12.2 0.4 1.1 9.3 0.4 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Mito_carr PF00153.22 KOS21406.1 - 4.3e-60 199.4 1.4 2.6e-22 78.3 0.1 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein HrpB7 PF09486.5 KOS21408.1 - 0.023 14.6 1.2 0.052 13.4 0.2 1.9 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DivIVA PF05103.8 KOS21408.1 - 0.077 13.0 1.2 0.11 12.5 0.2 1.7 2 0 0 2 2 2 0 DivIVA protein MtrF PF09472.5 KOS21408.1 - 0.092 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF1664 PF07889.7 KOS21408.1 - 0.12 12.2 1.3 0.32 10.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TRI5 PF06330.6 KOS21408.1 - 0.12 10.9 0.1 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) DUF3715 PF12509.3 KOS21408.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) MBOAT PF03062.14 KOS21410.1 - 1e-42 146.4 17.9 1e-42 146.4 12.4 2.6 3 1 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family PLDc_2 PF13091.1 KOS21411.1 - 1.2e-13 50.8 0.0 5.6e-07 29.3 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.17 KOS21411.1 - 1.5e-12 46.8 2.1 2.1e-06 27.3 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif GLTP PF08718.6 KOS21412.1 - 8.4e-44 149.2 0.0 1.3e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Ribonucleas_3_3 PF14622.1 KOS21414.1 - 1.1e-09 38.3 0.0 0.001 19.0 0.1 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KOS21414.1 - 3.5e-06 27.4 0.0 8.8e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 KOS21414.1 - 9.9e-05 22.8 0.0 0.00026 21.5 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Mito_fiss_reg PF05308.6 KOS21414.1 - 0.19 11.0 9.8 0.36 10.1 6.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator PsbQ PF05757.6 KOS21414.1 - 0.42 9.9 5.4 0.73 9.2 3.7 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) DUF605 PF04652.11 KOS21414.1 - 1.6 8.0 10.8 2.3 7.5 7.5 1.2 1 0 0 1 1 1 0 Vta1 like DUF2360 PF10152.4 KOS21414.1 - 7.8 6.7 8.1 20 5.4 5.6 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) p450 PF00067.17 KOS21415.1 - 6.4e-72 242.5 0.0 9e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.20 KOS21415.1 - 5.8e-24 84.7 0.0 1.5e-23 83.3 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.15 KOS21415.1 - 3e-20 72.5 0.0 6.4e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KOS21415.1 - 2.7e-12 47.2 0.0 8.1e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FMN_red PF03358.10 KOS21415.1 - 0.0055 16.2 0.0 0.91 9.0 0.0 2.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.2 KOS21415.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_NdrI PF07972.6 KOS21415.1 - 0.037 13.9 0.0 0.22 11.4 0.0 2.3 3 0 0 3 3 3 0 NrdI Flavodoxin like zf-RING_2 PF13639.1 KOS21416.1 - 3.7e-14 52.2 6.3 5.6e-14 51.6 4.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KOS21416.1 - 2e-09 36.9 4.2 2.9e-09 36.4 2.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS21416.1 - 3.2e-07 30.2 6.5 5e-07 29.6 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS21416.1 - 3.3e-07 29.8 5.8 5.3e-07 29.2 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KOS21416.1 - 1e-05 25.5 8.9 2.2e-05 24.4 6.2 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KOS21416.1 - 1.5e-05 24.6 3.6 2.3e-05 24.0 2.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KOS21416.1 - 0.00077 19.2 1.5 0.0016 18.2 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KOS21416.1 - 0.0012 18.3 2.3 0.0021 17.5 1.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF2370 PF10176.4 KOS21416.1 - 0.0021 17.4 0.5 0.0047 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) PHD PF00628.24 KOS21416.1 - 0.065 12.9 5.5 0.11 12.2 3.8 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 KOS21416.1 - 0.1 12.6 6.8 0.22 11.6 4.7 1.6 1 1 0 1 1 1 0 RING-variant domain Baculo_RING PF05883.6 KOS21416.1 - 0.13 12.1 1.6 0.26 11.1 1.1 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-Nse PF11789.3 KOS21416.1 - 0.16 11.5 1.6 0.32 10.5 1.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KOS21416.1 - 0.55 9.8 3.6 0.96 9.0 2.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain BRO1 PF03097.13 KOS21417.1 - 2.5e-133 444.4 0.7 2.5e-133 444.4 0.5 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KOS21417.1 - 6.3e-90 301.1 22.3 1.2e-89 300.2 15.4 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV CorA PF01544.13 KOS21418.1 - 0.0028 16.7 0.4 0.0054 15.8 0.3 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Kelch_3 PF13415.1 KOS21419.1 - 2.6e-19 68.8 27.6 6.9e-06 26.0 0.1 9.7 9 1 0 9 9 9 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KOS21419.1 - 6.7e-19 67.4 9.2 7.7e-06 25.7 0.0 7.4 7 1 0 7 7 7 4 Kelch motif Kelch_2 PF07646.10 KOS21419.1 - 1.5e-14 53.1 6.2 4.8e-06 26.1 0.0 6.8 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.1 KOS21419.1 - 3.7e-14 52.2 19.4 4.4e-05 23.1 0.1 7.7 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_6 PF13964.1 KOS21419.1 - 6.1e-12 45.1 7.5 6.4e-05 22.9 0.0 6.1 5 2 2 7 7 7 3 Kelch motif Kelch_1 PF01344.20 KOS21419.1 - 8.6e-12 44.4 7.4 0.0037 16.7 0.0 5.9 7 0 0 7 7 7 4 Kelch motif 2Fe-2S_thioredx PF01257.14 KOS21420.1 - 9.5e-59 197.1 0.0 1.2e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Senescence PF06911.7 KOS21420.1 - 0.093 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Senescence-associated protein Glyco_hydro_43 PF04616.9 KOS21422.1 - 1.9e-51 174.8 3.3 2.3e-51 174.5 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1080 PF06439.6 KOS21422.1 - 2.1e-07 31.0 0.0 3.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Glyco_hydro_12 PF01670.11 KOS21422.1 - 0.0039 17.0 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 p450 PF00067.17 KOS21423.1 - 2.4e-58 197.8 0.0 2.8e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KOS21424.1 - 0.0023 16.5 0.0 0.0026 16.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.1 KOS21424.1 - 0.2 10.9 0.4 0.65 9.3 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) ATP_synt_I PF03899.10 KOS21424.1 - 3.9 7.6 8.6 69 3.6 5.5 2.4 2 1 0 2 2 2 0 ATP synthase I chain ERO1 PF04137.10 KOS21425.1 - 1e-131 439.2 0.0 3.1e-131 437.6 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) CKS PF01111.14 KOS21426.1 - 5.2e-29 99.8 0.6 7.3e-29 99.3 0.4 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit HVSL PF09749.4 KOS21427.1 - 7.4e-34 116.8 0.0 1.1e-33 116.2 0.0 1.2 1 1 0 1 1 1 1 Uncharacterised conserved protein TGFb_propeptide PF00688.13 KOS21427.1 - 0.12 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 TGF-beta propeptide P120R PF08062.6 KOS21428.1 - 0.35 11.2 10.4 2 8.8 4.6 3.0 2 0 0 2 2 2 0 P120R (NUC006) repeat MIP-T3 PF10243.4 KOS21428.1 - 0.94 7.8 41.4 0.2 10.0 22.1 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CS PF04969.11 KOS21429.1 - 5.3e-15 55.7 0.0 8.6e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 CS domain UQ_con PF00179.21 KOS21430.1 - 1.1e-34 118.8 0.0 1.7e-34 118.2 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme IlvN PF07991.7 KOS21431.1 - 2.4e-45 153.8 0.0 3.7e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KOS21431.1 - 2.1e-42 144.4 0.0 3e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KOS21431.1 - 0.15 12.5 0.7 0.43 11.0 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PRP1_N PF06424.7 KOS21432.1 - 1.1e-49 168.1 7.6 2.4e-49 167.0 5.3 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KOS21432.1 - 1.6e-24 84.1 42.3 0.013 16.1 0.0 14.8 5 3 10 15 15 15 10 Tetratricopeptide repeat TPR_16 PF13432.1 KOS21432.1 - 6.4e-18 64.9 26.3 9e-05 23.0 2.2 8.9 6 2 2 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 KOS21432.1 - 5.1e-17 61.9 22.6 0.0014 18.9 0.0 10.2 6 3 3 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 KOS21432.1 - 1e-09 37.8 16.3 0.019 14.5 0.2 8.5 6 3 4 10 10 10 3 TPR repeat TPR_2 PF07719.12 KOS21432.1 - 2.7e-06 26.8 18.2 0.086 12.7 0.1 8.9 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 KOS21432.1 - 1.6e-05 24.3 1.4 0.024 14.3 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 KOS21432.1 - 1.8e-05 24.5 7.9 1.7 9.0 0.1 8.4 10 1 1 11 11 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS21432.1 - 0.00041 19.9 1.6 5.5 7.0 0.0 5.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 KOS21432.1 - 0.0023 17.8 10.1 1.5 8.8 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KOS21432.1 - 0.0061 16.9 7.7 7.9 7.1 0.0 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 KOS21432.1 - 0.024 14.4 9.7 0.1 12.4 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KOS21432.1 - 0.031 13.8 3.0 2.4 7.8 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 KOS21432.1 - 0.19 11.6 0.0 0.19 11.6 0.0 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat Apolipoprotein PF01442.13 KOS21433.1 - 0.00015 21.3 0.0 0.00018 21.1 0.0 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF3752 PF12572.3 KOS21433.1 - 0.0029 17.7 0.7 0.004 17.2 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) LPP PF04728.8 KOS21433.1 - 0.0067 16.1 1.7 0.021 14.6 1.2 1.9 1 1 0 1 1 1 1 Lipoprotein leucine-zipper Prominin PF05478.6 KOS21433.1 - 0.022 12.3 0.4 0.028 11.9 0.3 1.0 1 0 0 1 1 1 0 Prominin DUF2514 PF10721.4 KOS21433.1 - 0.03 14.0 0.8 0.035 13.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DUF3072 PF11272.3 KOS21433.1 - 0.081 12.5 1.5 1 9.0 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3072) Phasin PF05597.6 KOS21433.1 - 0.3 10.8 2.8 0.55 10.0 0.6 1.9 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF883 PF05957.8 KOS21433.1 - 0.6 10.5 4.3 1 9.7 1.5 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ISG65-75 PF11727.3 KOS21433.1 - 3.5 6.5 7.6 6.1 5.8 5.3 1.4 1 1 0 1 1 1 0 Invariant surface glycoprotein TIMELESS_C PF05029.8 KOS21434.1 - 0.01 14.8 10.0 0.015 14.2 6.9 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region SSP160 PF06933.6 KOS21434.1 - 0.31 8.9 2.9 0.58 8.0 2.0 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ribosomal_L16 PF00252.13 KOS21435.1 - 1.5e-31 108.8 0.0 2e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF946 PF06101.6 KOS21436.1 - 2.9e-11 42.0 0.7 6.1e-11 41.0 0.5 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) DUF2730 PF10805.3 KOS21437.1 - 0.071 12.8 0.4 0.28 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Vac7 PF12751.2 KOS21438.1 - 4.8e-111 371.3 7.3 4.8e-111 371.3 5.1 2.2 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 RrnaAD PF00398.15 KOS21439.1 - 1.8e-57 194.3 0.0 2.4e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KOS21439.1 - 1.9e-09 37.5 0.0 3.6e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS21439.1 - 3.8e-06 27.4 0.0 7.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS21439.1 - 0.0002 20.7 0.0 0.00035 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KOS21439.1 - 0.00052 19.6 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS21439.1 - 0.00069 19.3 0.1 0.0017 18.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS21439.1 - 0.0012 19.3 0.6 0.0076 16.7 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain PCMT PF01135.14 KOS21439.1 - 0.0021 17.6 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 KOS21439.1 - 0.0027 16.9 0.0 0.0057 15.8 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 KOS21439.1 - 0.005 15.9 0.0 0.0077 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 KOS21439.1 - 0.022 13.8 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 KOS21439.1 - 0.038 14.3 0.0 0.096 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RRN3 PF05327.6 KOS21439.1 - 0.59 8.1 3.4 0.93 7.5 2.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ribosomal_L7Ae PF01248.21 KOS21440.1 - 1.6e-25 88.4 0.0 1.8e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HSP70 PF00012.15 KOS21442.1 - 2.9e-166 553.9 3.7 2.9e-166 553.9 2.6 1.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KOS21442.1 - 4.6e-12 45.1 0.0 4.6e-12 45.1 0.0 2.5 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.1 KOS21442.1 - 1.4e-06 28.0 0.2 0.12 12.1 0.0 3.5 2 1 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 KOS21442.1 - 0.12 11.9 4.2 0.55 9.8 0.0 3.0 3 0 0 3 3 3 0 FGGY family of carbohydrate kinases, C-terminal domain V_ATPase_I PF01496.14 KOS21442.1 - 2.1 6.1 7.0 3.1 5.5 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vps52 PF04129.7 KOS21444.1 - 1e-120 403.7 0.2 1.3e-120 403.3 0.1 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 KOS21444.1 - 0.00012 20.4 1.2 0.00023 19.4 0.0 1.8 1 1 1 2 2 2 1 Exocyst complex component Sec3 ANTAR PF03861.9 KOS21444.1 - 0.08 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 ANTAR domain eIF-5a PF01287.15 KOS21445.1 - 1.7e-21 75.9 0.2 2.4e-21 75.4 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KOS21445.1 - 3.1e-05 23.5 0.8 5.7e-05 22.6 0.6 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KOS21445.1 - 0.074 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain FAD_binding_1 PF00667.15 KOS21446.1 - 3.4e-31 108.3 0.0 1.9e-28 99.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Flavodoxin_1 PF00258.20 KOS21446.1 - 5.2e-29 101.0 0.0 7.8e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KOS21446.1 - 3e-13 50.2 0.0 7.6e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 KOS21446.1 - 0.09 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain RRN7 PF11781.3 KOS21447.1 - 3.3e-08 32.9 1.4 5.8e-08 32.1 1.0 1.3 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 ArfGap PF01412.13 KOS21448.1 - 1.2e-32 112.1 0.2 2e-32 111.4 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SAP PF02037.22 KOS21449.1 - 6.3e-12 44.6 0.3 1.1e-11 43.9 0.2 1.4 1 0 0 1 1 1 1 SAP domain RRM_5 PF13893.1 KOS21449.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GATase PF00117.23 KOS21450.1 - 7.4e-46 156.0 0.0 1e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 KOS21450.1 - 8.3e-46 154.7 0.0 1.3e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 KOS21450.1 - 8.5e-07 28.6 0.1 6.3e-05 22.5 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 KOS21450.1 - 0.052 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Yip1 PF04893.12 KOS21451.1 - 7.2e-12 45.1 18.1 7.2e-12 45.1 12.5 1.4 1 1 0 1 1 1 1 Yip1 domain YjgP_YjgQ PF03739.9 KOS21451.1 - 4.5 5.9 10.1 0.033 12.9 1.2 1.6 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Ribosomal_L22e PF01776.12 KOS21452.1 - 2.6e-47 159.4 1.6 3.2e-47 159.1 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Mito_carr PF00153.22 KOS21453.1 - 1.3e-53 178.7 0.5 5.4e-20 70.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein G-patch PF01585.18 KOS21454.1 - 3.8e-12 45.7 0.4 1e-11 44.4 0.3 1.8 1 0 0 1 1 1 1 G-patch domain Mito_fiss_reg PF05308.6 KOS21454.1 - 0.078 12.3 1.7 0.12 11.7 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Cwf_Cwc_15 PF04889.7 KOS21454.1 - 0.56 9.8 8.9 1.1 8.9 6.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.5 KOS21454.1 - 0.85 9.9 9.7 2 8.7 2.7 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Anp1 PF03452.9 KOS21456.1 - 9.4e-107 356.1 0.0 1.1e-106 355.8 0.0 1.1 1 0 0 1 1 1 1 Anp1 HdeA PF06411.6 KOS21456.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 HdeA/HdeB family p450 PF00067.17 KOS21457.1 - 1.2e-52 179.0 0.0 1.8e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KOS21458.1 - 7e-43 146.3 0.0 1.1e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS21458.1 - 2.6e-08 33.6 8.0 6.5e-08 32.3 5.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 KOS21459.1 - 1e-09 38.6 0.0 2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS21459.1 - 3.8e-06 27.0 0.0 1.2e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KOS21459.1 - 9.3e-05 22.1 0.1 0.00031 20.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KOS21459.1 - 0.00036 20.2 0.4 0.0014 18.2 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 KOS21459.1 - 0.0005 19.1 0.0 0.00086 18.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KOS21459.1 - 0.0015 18.4 0.0 0.0039 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KOS21459.1 - 0.0026 17.6 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS21459.1 - 0.0029 18.4 0.1 0.019 15.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS21459.1 - 0.005 16.8 0.7 0.052 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 KOS21459.1 - 0.0082 14.8 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein DTW PF03942.10 KOS21459.1 - 0.011 14.9 0.0 0.058 12.5 0.1 2.0 2 0 0 2 2 2 0 DTW domain Zeta_toxin PF06414.7 KOS21459.1 - 0.02 13.9 0.0 0.047 12.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 KOS21459.1 - 0.063 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KOS21459.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.1 KOS21459.1 - 0.072 13.0 0.2 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KOS21459.1 - 0.089 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KOS21459.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 KOS21459.1 - 0.13 12.5 0.1 0.37 11.0 0.1 1.8 1 0 0 1 1 1 0 ABC transporter Mcp5_PH PF12814.2 KOS21460.1 - 1.7e-47 160.3 0.0 2.6e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology OTU PF02338.14 KOS21461.1 - 7.9e-18 65.2 2.6 4.7e-17 62.7 0.3 2.7 2 1 0 2 2 2 1 OTU-like cysteine protease DUF2357 PF09823.4 KOS21461.1 - 0.025 13.6 0.7 0.66 9.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) Chitin_synth_1 PF01644.12 KOS21462.1 - 5.7e-69 231.0 0.0 8.4e-69 230.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KOS21462.1 - 8.4e-28 97.0 0.2 1.1e-22 80.0 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 KOS21462.1 - 9.5e-27 92.5 0.1 1.7e-26 91.7 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 KOS21462.1 - 3.3e-11 43.2 0.1 3.3e-11 43.2 0.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KOS21462.1 - 2.6e-09 37.2 0.0 9.3e-09 35.4 0.0 2.0 3 0 0 3 3 3 1 Glycosyltransferase like family 2 UAA PF08449.6 KOS21463.1 - 1.7e-13 50.1 18.1 2.1e-13 49.8 12.6 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KOS21463.1 - 1.3e-08 34.6 6.7 1.3e-08 34.6 4.6 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KOS21463.1 - 0.011 15.7 27.8 0.013 15.5 3.6 2.5 2 0 0 2 2 2 0 EamA-like transporter family ArfGap PF01412.13 KOS21464.1 - 6.2e-39 132.3 1.2 2.5e-38 130.4 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.26 KOS21464.1 - 2.5e-05 23.9 0.0 5.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain NMD3 PF04981.8 KOS21464.1 - 0.0086 15.2 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 NMD3 family DUF1840 PF08895.6 KOS21466.1 - 0.32 11.0 2.2 2 8.5 1.5 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) ECH PF00378.15 KOS21467.1 - 2.2e-36 125.2 2.5 7.5e-23 80.9 2.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KOS21467.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Ku PF02735.11 KOS21469.1 - 9.1e-40 136.1 0.0 1.9e-39 135.1 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KOS21469.1 - 1.4e-32 112.9 0.0 2.2e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 KOS21469.1 - 2.1e-12 47.4 1.1 5e-12 46.1 0.1 2.2 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 KOS21469.1 - 3.4e-09 35.9 0.1 8.6e-09 34.7 0.1 1.8 1 0 0 1 1 1 1 SAP domain Toprim_3 PF13362.1 KOS21469.1 - 0.00023 21.3 0.2 0.1 12.8 0.0 3.5 3 1 1 4 4 4 1 Toprim domain Ferrochelatase PF00762.14 KOS21470.1 - 2.7e-92 309.1 0.0 3.2e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Septin PF00735.13 KOS21471.1 - 2.3e-120 400.8 0.1 2.3e-120 400.8 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KOS21471.1 - 4.2e-07 29.9 0.0 1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KOS21471.1 - 1.7e-05 25.1 1.0 0.02 15.2 0.0 2.5 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 KOS21471.1 - 5e-05 22.5 0.3 0.00043 19.4 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KOS21471.1 - 0.00016 21.1 1.9 0.00084 18.8 0.0 2.8 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KOS21471.1 - 0.00024 20.6 0.0 0.0013 18.2 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AIG1 PF04548.11 KOS21471.1 - 0.0012 18.0 1.9 0.0023 17.0 0.0 2.2 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 KOS21471.1 - 0.0018 18.3 0.2 0.012 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 KOS21471.1 - 0.0028 18.1 0.4 0.01 16.3 0.0 2.2 2 1 0 2 2 1 1 Miro-like protein Ras PF00071.17 KOS21471.1 - 0.0049 16.2 0.2 0.04 13.2 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.1 KOS21471.1 - 0.0066 16.6 0.0 0.03 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KOS21471.1 - 0.0082 15.6 0.7 0.02 14.3 0.0 2.0 2 0 0 2 2 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 KOS21471.1 - 0.0092 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Exonuc_VII_L PF02601.10 KOS21471.1 - 0.027 13.6 6.2 0.047 12.8 4.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dynamin_N PF00350.18 KOS21471.1 - 0.028 14.2 8.4 0.44 10.3 0.0 3.5 3 1 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 KOS21471.1 - 0.031 13.8 0.1 7 6.1 0.0 3.1 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 KOS21471.1 - 0.055 13.1 1.9 0.21 11.2 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 KOS21471.1 - 0.11 12.1 1.4 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KOS21471.1 - 0.11 11.8 0.1 0.41 10.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KOS21471.1 - 0.11 12.6 0.4 0.59 10.3 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_32 PF13654.1 KOS21471.1 - 0.17 10.5 11.8 0.46 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain YlqD PF11068.3 KOS21471.1 - 0.18 11.8 12.0 0.35 10.8 8.4 1.5 1 0 0 1 1 1 0 YlqD protein Strep_SA_rep PF06696.6 KOS21471.1 - 0.18 11.6 3.2 0.22 11.2 1.0 2.0 1 1 1 2 2 2 0 Streptococcal surface antigen repeat Phage_GPO PF05929.6 KOS21471.1 - 0.49 9.6 6.7 0.76 8.9 4.6 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF87 PF01935.12 KOS21471.1 - 0.89 9.3 7.0 2.9 7.6 0.0 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 DUF2937 PF11157.3 KOS21471.1 - 1.2 8.4 4.5 2.3 7.5 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) IncA PF04156.9 KOS21471.1 - 1.3 8.5 10.7 2.1 7.9 7.4 1.3 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KOS21471.1 - 2.9 5.6 9.0 4.4 5.0 6.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KfrA_N PF11740.3 KOS21471.1 - 4.6 7.7 11.0 8 6.9 7.6 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Atg14 PF10186.4 KOS21471.1 - 6.2 5.6 9.9 10 4.9 6.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Amidohydro_1 PF01979.15 KOS21472.1 - 1.9e-45 156.0 0.3 2.3e-45 155.7 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KOS21472.1 - 7.5e-10 38.5 8.8 3.4e-08 33.1 2.8 2.4 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KOS21472.1 - 1.8e-06 27.6 0.0 6.6e-06 25.8 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KOS21472.1 - 4.7e-05 23.5 6.8 0.00021 21.4 4.7 2.1 1 1 0 1 1 1 1 Amidohydrolase tRNA_int_end_N2 PF12928.2 KOS21472.1 - 0.021 14.2 0.0 0.057 12.8 0.0 1.7 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term Ribonuclease_T2 PF00445.13 KOS21474.1 - 1.1e-44 152.3 0.2 1.5e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Abhydrolase_3 PF07859.8 KOS21475.1 - 4.5e-40 137.4 0.0 6.3e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KOS21475.1 - 7.2e-07 28.2 0.2 2.1e-06 26.7 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KOS21475.1 - 0.00013 21.7 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS21475.1 - 0.00054 19.2 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KOS21475.1 - 0.021 14.3 0.2 0.1 12.0 0.0 2.1 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase tRNA-synt_2 PF00152.15 KOS21476.1 - 1.3e-73 247.7 0.1 2.1e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 KOS21476.1 - 9.3e-14 50.9 0.1 1.6e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 KOS21476.1 - 6e-05 22.8 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KOS21476.1 - 0.00055 19.2 0.1 0.25 10.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FMN_dh PF01070.13 KOS21477.1 - 5.5e-121 403.7 0.2 6.9e-121 403.4 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KOS21477.1 - 8.7e-19 67.1 0.0 2.7e-18 65.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KOS21477.1 - 3.8e-08 32.6 0.0 6.1e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KOS21477.1 - 0.00076 18.4 0.0 0.0017 17.3 0.0 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KOS21477.1 - 0.0058 15.8 0.2 0.0091 15.1 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 KOS21477.1 - 0.049 12.8 2.7 0.75 9.0 0.1 2.6 2 1 0 3 3 3 0 Histidine biosynthesis protein RabGAP-TBC PF00566.13 KOS21478.1 - 3.1e-22 79.1 0.0 4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MIF4G PF02854.14 KOS21479.1 - 1.4e-51 174.8 0.0 5.1e-28 97.9 0.0 3.7 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 KOS21479.1 - 3e-18 66.1 21.2 3e-18 66.1 14.7 2.3 3 0 0 3 3 3 1 Up-frameshift suppressor 2 APG6 PF04111.7 KOS21479.1 - 3.4 6.6 12.1 36 3.2 0.0 2.5 2 0 0 2 2 2 0 Autophagy protein Apg6 GCP5-Mod21 PF14609.1 KOS21479.1 - 5.4 5.0 11.0 11 4.0 7.7 1.4 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 TCTP PF00838.12 KOS21479.1 - 6 6.8 10.1 16 5.4 0.3 2.5 2 0 0 2 2 2 0 Translationally controlled tumour protein GTP_EFTU PF00009.22 KOS21480.1 - 3.9e-32 111.2 0.0 3.9e-32 111.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KOS21480.1 - 3.2e-18 65.5 0.0 8.6e-18 64.2 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KOS21480.1 - 9.8e-09 35.2 8.4 3.6e-08 33.3 0.1 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KOS21480.1 - 7.3e-07 29.1 0.0 2.4e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KOS21480.1 - 0.00048 19.7 0.0 0.0014 18.2 0.0 1.9 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Miro PF08477.8 KOS21480.1 - 0.0018 18.7 0.0 0.0084 16.6 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 KOS21480.1 - 0.035 14.2 0.1 0.55 10.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain LysM PF01476.15 KOS21481.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 LysM domain Fungal_trans PF04082.13 KOS21482.1 - 6.1e-37 126.9 0.0 3.5e-36 124.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS21482.1 - 0.0016 18.2 1.3 0.0031 17.3 0.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP_synt_H PF05493.8 KOS21483.1 - 4.1e-17 62.0 2.9 6.2e-17 61.4 2.0 1.3 1 1 0 1 1 1 1 ATP synthase subunit H PRA1 PF03208.14 KOS21483.1 - 0.03 13.6 0.4 0.032 13.5 0.3 1.0 1 0 0 1 1 1 0 PRA1 family protein AzlD PF05437.7 KOS21483.1 - 0.049 13.5 2.9 3.9 7.4 1.4 2.0 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) Got1 PF04178.7 KOS21483.1 - 0.06 13.4 0.9 0.063 13.3 0.7 1.1 1 0 0 1 1 1 0 Got1/Sft2-like family Corona_5a PF06336.6 KOS21483.1 - 0.069 13.0 0.4 0.086 12.7 0.2 1.1 1 0 0 1 1 1 0 Coronavirus 5a protein DUF843 PF05814.6 KOS21483.1 - 0.098 12.4 0.1 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) LRR19-TM PF15176.1 KOS21483.1 - 0.12 12.0 0.2 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Arv1 PF04161.8 KOS21484.1 - 5.8e-46 157.0 0.0 7.5e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family Nodulin-like PF06813.8 KOS21485.1 - 4.1e-14 52.4 2.4 9.1e-14 51.3 1.6 1.6 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 KOS21485.1 - 9.3e-14 50.8 32.8 4.8e-11 41.9 14.1 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Serinc PF03348.10 KOS21486.1 - 6.1e-153 509.5 4.8 7e-153 509.3 3.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Phosphoesterase PF04185.9 KOS21486.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoesterase family Carn_acyltransf PF00755.15 KOS21487.1 - 3.5e-180 600.0 0.0 4e-180 599.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ETF PF01012.16 KOS21488.1 - 3.3e-40 137.4 1.3 4.7e-40 136.9 0.2 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 KOS21488.1 - 1.1e-35 121.1 0.3 2.1e-35 120.1 0.2 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain CAP_N PF01213.14 KOS21490.1 - 1.5e-86 290.5 0.3 2e-86 290.1 0.2 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KOS21490.1 - 3.8e-53 179.0 0.9 5e-53 178.6 0.7 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KOS21490.1 - 0.013 14.9 1.6 0.39 10.1 0.5 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C DUF2868 PF11067.3 KOS21490.1 - 2.8 7.0 6.0 0.35 9.9 1.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) Hydrophobin_2 PF06766.6 KOS21491.1 - 1.9e-20 72.2 9.4 2.4e-20 71.9 6.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin cEGF PF12662.2 KOS21491.1 - 0.066 12.8 1.1 0.14 11.8 0.7 1.5 1 0 0 1 1 1 0 Complement Clr-like EGF-like Thioredoxin_4 PF13462.1 KOS21493.1 - 0.00018 21.5 0.0 0.00053 20.0 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 KOS21493.1 - 0.00098 18.7 1.8 0.53 9.8 0.1 3.0 2 1 0 2 2 2 2 DSBA-like thioredoxin domain DUF59 PF01883.14 KOS21495.1 - 0.017 15.1 0.3 0.049 13.6 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function DUF59 GTP_EFTU PF00009.22 KOS21496.1 - 3.9e-43 147.0 0.0 5.9e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KOS21496.1 - 4.5e-28 97.2 0.0 1.4e-27 95.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KOS21496.1 - 2.7e-17 62.3 0.0 7e-17 61.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KOS21496.1 - 1.1e-08 35.1 0.1 2.6e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KOS21496.1 - 2.3e-07 30.5 0.2 1.5e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KOS21496.1 - 5.5e-05 23.1 0.1 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KOS21496.1 - 0.00059 20.3 0.0 0.0014 19.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KOS21496.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Ras family Thiolase_N PF00108.18 KOS21497.1 - 2.3e-96 321.8 0.5 2.3e-96 321.8 0.3 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KOS21497.1 - 1.4e-45 153.6 1.0 2.7e-44 149.5 0.2 2.5 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KOS21497.1 - 5.6e-06 26.0 1.1 0.00043 19.8 0.3 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KOS21497.1 - 0.3 10.7 3.1 5.9 6.6 0.0 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sin3_corepress PF08295.7 KOS21498.1 - 6.2e-39 131.8 0.0 1.8e-38 130.3 0.0 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 KOS21498.1 - 1.8e-26 91.4 1.6 2.1e-18 65.6 0.5 2.7 2 0 0 2 2 2 2 Paired amphipathic helix repeat Spt20 PF12090.3 KOS21499.1 - 0.0046 16.3 1.2 0.0062 15.9 0.8 1.3 1 0 0 1 1 1 1 Spt20 family DUF1777 PF08648.7 KOS21499.1 - 0.021 14.5 14.0 0.15 11.7 6.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) RAB3GAP2_N PF14655.1 KOS21499.1 - 0.025 13.5 2.9 0.036 13.0 2.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PAH PF02671.16 KOS21499.1 - 0.034 13.7 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Paired amphipathic helix repeat DUF533 PF04391.7 KOS21499.1 - 0.057 12.7 8.7 0.11 11.8 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Glt_symporter PF03616.9 KOS21499.1 - 0.084 11.3 1.1 0.12 10.8 0.7 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF3371 PF11851.3 KOS21499.1 - 0.19 12.4 10.2 1.1 9.9 5.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) FimP PF09766.4 KOS21499.1 - 0.19 10.7 16.4 0.088 11.8 7.6 2.0 2 0 0 2 2 2 0 Fms-interacting protein VIT1 PF01988.14 KOS21499.1 - 0.45 9.9 3.0 0.55 9.6 0.3 1.9 2 0 0 2 2 2 0 VIT family Pex16 PF08610.5 KOS21499.1 - 0.52 9.2 3.1 0.91 8.4 2.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) BRF1 PF07741.8 KOS21499.1 - 2.2 8.5 9.1 0.91 9.7 2.1 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain eIF-3_zeta PF05091.7 KOS21499.1 - 3.4 6.1 9.5 0.18 10.3 1.7 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pex14_N PF04695.8 KOS21499.1 - 8.8 6.3 13.3 1.5 8.8 6.0 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HIG_1_N PF04588.8 KOS21500.1 - 4.5e-22 77.5 0.5 4.5e-22 77.5 0.4 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF2637 PF10935.3 KOS21500.1 - 0.0074 16.2 1.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2637) Lin-8 PF03353.10 KOS21500.1 - 0.017 14.4 7.9 0.024 13.9 5.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MAS20 PF02064.10 KOS21500.1 - 0.024 14.5 1.2 0.051 13.4 0.8 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor CENP-T PF15511.1 KOS21500.1 - 0.03 13.5 6.7 0.038 13.2 4.7 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1772 PF08592.6 KOS21500.1 - 0.092 12.4 0.0 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF3394 PF11874.3 KOS21500.1 - 4.8 6.6 7.5 5.9 6.3 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3394) DUF2681 PF10883.3 KOS21500.1 - 5.9 7.1 13.3 1.5e+02 2.6 7.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) COX14 PF14880.1 KOS21500.1 - 7.5 6.2 6.2 37 4.0 1.7 3.2 3 1 0 3 3 3 0 Cytochrome oxidase c assembly ZZ PF00569.12 KOS21501.1 - 1.7e-10 40.2 7.7 3.1e-10 39.4 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 KOS21501.1 - 5.9e-08 31.4 11.2 0.0028 16.8 0.2 4.1 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 KOS21501.1 - 5.4e-06 25.8 5.8 0.014 15.2 0.2 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 KOS21501.1 - 0.00026 21.0 9.7 0.00057 19.9 2.6 4.2 3 1 2 5 5 5 3 EF-hand domain pair C1_3 PF07649.7 KOS21501.1 - 0.027 14.5 9.1 0.046 13.7 6.3 1.4 1 0 0 1 1 1 0 C1-like domain TLD PF07534.11 KOS21503.1 - 2.6e-29 102.0 0.0 4.3e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 TLD MUG2_C PF08593.5 KOS21503.1 - 8.6e-05 22.6 0.0 0.00027 21.0 0.0 1.9 2 0 0 2 2 2 1 Meiotically up-regulated glycoproteins C-terminal TFIIA PF03153.8 KOS21503.1 - 0.34 10.7 6.1 0.49 10.2 4.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PBP1_TM PF14812.1 KOS21503.1 - 2.7 8.3 10.7 5.8 7.3 7.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.7 KOS21503.1 - 3.6 7.2 7.5 5.6 6.6 5.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 KOS21503.1 - 4 6.9 6.2 6.8 6.1 4.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 KOS21503.1 - 9.8 5.3 7.4 14 4.7 5.1 1.1 1 0 0 1 1 1 0 NOA36 protein Abhydrolase_6 PF12697.2 KOS21504.1 - 1.1e-12 48.3 3.4 1.2e-12 48.1 2.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS21504.1 - 0.0029 17.3 0.0 0.0054 16.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Translin PF01997.11 KOS21505.1 - 2.9e-49 167.4 0.0 3.4e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Translin family Hemerythrin PF01814.18 KOS21505.1 - 0.03 14.4 1.4 0.064 13.4 0.7 1.8 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain EcoEI_R_C PF08463.5 KOS21505.1 - 0.14 12.0 0.7 0.21 11.4 0.5 1.4 1 0 0 1 1 1 0 EcoEI R protein C-terminal VIT1 PF01988.14 KOS21506.1 - 3.8e-53 180.1 8.1 4.7e-53 179.8 5.6 1.1 1 0 0 1 1 1 1 VIT family ATP_synt_I PF03899.10 KOS21506.1 - 3.1 7.9 12.3 0.1 12.7 2.2 2.7 2 1 0 2 2 2 0 ATP synthase I chain DUF1700 PF08006.6 KOS21506.1 - 6.5 6.0 12.9 1 8.6 5.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Ada_Zn_binding PF02805.11 KOS21507.1 - 1.6e-30 104.4 5.5 2.9e-30 103.6 3.8 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 KOS21507.1 - 4.1e-07 29.6 0.0 7.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 KOS21507.1 - 4.6e-05 23.4 0.3 0.00014 21.9 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain Antiterm PF03589.8 KOS21507.1 - 0.056 13.5 0.1 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Antitermination protein Mannosyl_trans PF05007.8 KOS21508.1 - 1.1e-78 264.4 12.8 1.4e-78 264.0 8.9 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KOS21508.1 - 5.4e-11 41.9 18.9 8.9e-11 41.2 13.1 1.3 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 KOS21508.1 - 1.5e-06 27.8 26.1 1.5e-06 27.8 18.1 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF2029) MARVEL PF01284.18 KOS21510.1 - 1.5e-09 37.8 15.3 3.9e-09 36.4 10.7 1.7 1 1 0 1 1 1 1 Membrane-associating domain Borrelia_P83 PF05262.6 KOS21510.1 - 0.01 14.1 6.1 0.012 13.9 4.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1183 PF06682.7 KOS21510.1 - 0.014 15.0 5.8 0.028 14.0 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) FHIPEP PF00771.15 KOS21510.1 - 0.043 12.1 8.3 0.063 11.6 5.8 1.3 1 0 0 1 1 1 0 FHIPEP family DUF342 PF03961.8 KOS21510.1 - 0.05 12.0 4.5 0.063 11.6 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) OATP PF03137.15 KOS21510.1 - 0.13 10.2 3.0 0.31 9.0 2.1 1.6 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4557 PF15101.1 KOS21510.1 - 0.19 11.5 24.2 0.29 10.9 16.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AAA_23 PF13476.1 KOS21510.1 - 0.27 11.5 12.7 0.38 11.0 8.8 1.3 1 0 0 1 1 1 0 AAA domain Dala_Dala_lig_N PF01820.16 KOS21510.1 - 0.63 10.3 5.0 1.2 9.4 3.4 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus GNT-I PF03071.10 KOS21510.1 - 0.63 8.5 9.7 0.89 8.0 6.7 1.2 1 0 0 1 1 1 0 GNT-I family CDK5_activator PF03261.10 KOS21510.1 - 1.4 8.2 11.7 1.9 7.7 8.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DNA_pol3_a_NII PF11490.3 KOS21510.1 - 4.1 7.0 22.7 7.1 6.2 15.8 1.4 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II SAGA-Tad1 PF12767.2 KOS21510.1 - 5.7 6.5 18.7 8 6.0 13.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Cmc1 PF08583.5 KOS21511.1 - 1.1e-16 60.2 3.3 1.1e-16 60.2 2.3 1.8 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KOS21511.1 - 0.0037 17.1 2.4 1.7 8.6 0.1 2.4 2 0 0 2 2 2 2 CHCH domain COX17 PF05051.8 KOS21511.1 - 0.14 12.2 0.8 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.3 KOS21511.1 - 0.76 9.9 6.3 12 6.0 4.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Utp11 PF03998.8 KOS21512.1 - 4.1e-54 183.9 14.5 5e-54 183.6 10.1 1.1 1 0 0 1 1 1 1 Utp11 protein Nucleoplasmin PF03066.10 KOS21512.1 - 0.018 14.5 5.4 0.065 12.7 3.7 1.9 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 KOS21512.1 - 0.15 11.8 2.7 0.5 10.1 1.9 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4611 PF15387.1 KOS21512.1 - 1.2 9.3 9.8 0.041 14.0 1.4 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) tRNA-synt_2 PF00152.15 KOS21513.1 - 6.6e-88 294.6 0.0 8.8e-88 294.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KOS21513.1 - 0.12 11.5 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Ribosomal_S30 PF04758.9 KOS21514.1 - 9.6e-26 89.3 4.9 1.1e-25 89.1 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Cys_Met_Meta_PP PF01053.15 KOS21515.1 - 2.4e-25 88.6 0.0 3.3e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KOS21515.1 - 2.3e-07 30.1 0.0 3.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Apc4 PF12896.2 KOS21515.1 - 0.06 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 ADH_N PF08240.7 KOS21516.1 - 1.1e-28 99.1 0.6 3.1e-28 97.6 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KOS21516.1 - 3.8e-20 71.7 0.1 7e-20 70.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KOS21516.1 - 0.00022 22.1 0.0 0.00054 20.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AdoHcyase_NAD PF00670.16 KOS21516.1 - 0.0033 17.2 0.4 0.18 11.6 0.4 2.2 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HI0933_like PF03486.9 KOS21516.1 - 0.013 13.9 0.6 0.02 13.3 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Methyltransf_18 PF12847.2 KOS21516.1 - 0.018 15.5 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 KOS21516.1 - 0.067 12.5 0.2 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.9 KOS21516.1 - 0.8 9.5 3.1 1.6 8.5 1.1 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ANTH PF07651.11 KOS21517.1 - 1.9e-68 230.2 0.1 2.9e-68 229.6 0.1 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KOS21517.1 - 2e-08 34.1 0.0 3.7e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 ENTH domain MAT1 PF06391.8 KOS21518.1 - 2.8e-26 92.3 2.4 3.7e-26 91.9 1.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 KOS21518.1 - 3.1e-05 23.5 6.9 6e-05 22.6 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS21518.1 - 0.0004 20.3 6.3 0.00082 19.3 4.4 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS21518.1 - 0.0068 16.0 9.3 0.014 15.0 6.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MRP-S26 PF14943.1 KOS21518.1 - 0.0087 15.6 7.8 0.014 14.9 5.4 1.3 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 zf-RING_2 PF13639.1 KOS21518.1 - 0.022 14.6 6.8 0.069 12.9 4.8 1.8 1 1 1 2 2 2 0 Ring finger domain zf-piccolo PF05715.8 KOS21518.1 - 0.067 13.2 2.4 0.14 12.2 1.7 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING_5 PF14634.1 KOS21518.1 - 0.076 12.7 11.1 0.33 10.6 7.8 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 KOS21518.1 - 0.33 10.5 12.5 3.7 7.2 8.8 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KOS21518.1 - 0.42 10.5 4.2 0.91 9.4 2.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.1 KOS21518.1 - 0.68 9.7 8.2 20 5.0 5.6 2.3 1 1 1 2 2 2 0 Zinc-binding RING-finger CorA PF01544.13 KOS21518.1 - 0.78 8.7 2.3 1.1 8.2 1.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PigN PF04987.9 KOS21519.1 - 3.3e-25 88.6 12.1 2.9e-13 49.2 0.7 2.2 1 1 1 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KOS21519.1 - 9.4e-11 41.6 1.7 8.8e-08 31.8 0.4 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KOS21519.1 - 3.7e-09 36.2 0.3 8.2e-09 35.0 0.2 1.5 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KOS21519.1 - 0.00069 19.0 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily ETC_C1_NDUFA5 PF04716.9 KOS21520.1 - 4e-20 71.0 0.6 4e-20 71.0 0.4 2.0 3 0 0 3 3 3 1 ETC complex I subunit conserved region QLQ PF08880.6 KOS21520.1 - 0.082 12.3 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 QLQ Cys_Met_Meta_PP PF01053.15 KOS21521.1 - 2.6e-82 276.1 0.4 2.5e-48 164.2 0.0 3.0 1 1 2 3 3 3 3 Cys/Met metabolism PLP-dependent enzyme GDC-P PF02347.11 KOS21521.1 - 0.0011 17.7 0.1 0.0017 17.1 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 KOS21521.1 - 0.0062 14.8 0.0 0.0082 14.4 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase NIR_SIR_ferr PF03460.12 KOS21521.1 - 0.065 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain AAA PF00004.24 KOS21522.1 - 1.8e-19 70.2 0.2 1.7e-17 63.8 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KOS21522.1 - 3.9e-07 30.9 0.0 4.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KOS21522.1 - 1.5e-05 25.1 0.1 0.00024 21.2 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS21522.1 - 1.7e-05 24.7 0.0 1.8e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KOS21522.1 - 2.2e-05 24.1 0.5 0.00016 21.3 0.1 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KOS21522.1 - 2.7e-05 24.2 0.0 3.5e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 KOS21522.1 - 3.4e-05 23.8 0.1 0.0054 16.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KOS21522.1 - 3.7e-05 22.8 0.1 6.5e-05 22.0 0.1 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KOS21522.1 - 7.5e-05 21.9 0.0 7.5e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KOS21522.1 - 8e-05 22.9 0.0 9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KOS21522.1 - 0.0001 22.2 0.0 0.00022 21.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 KOS21522.1 - 0.00013 22.0 0.0 0.00015 21.8 0.0 1.1 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KOS21522.1 - 0.00014 21.1 0.2 0.00014 21.1 0.2 1.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KOS21522.1 - 0.00014 21.9 0.0 0.00017 21.7 0.0 1.2 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 KOS21522.1 - 0.00015 21.2 0.1 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 KOS21522.1 - 0.00025 21.0 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KOS21522.1 - 0.00037 19.3 0.0 0.00037 19.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 KOS21522.1 - 0.00097 18.5 0.6 0.0081 15.5 0.2 1.9 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 KOS21522.1 - 0.0016 17.2 0.3 0.0065 15.2 0.1 1.8 1 1 1 2 2 2 1 TIP49 C-terminus NACHT PF05729.7 KOS21522.1 - 0.0021 17.7 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 NACHT domain Sigma54_activat PF00158.21 KOS21522.1 - 0.0028 17.1 0.0 0.005 16.3 0.0 1.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.22 KOS21522.1 - 0.0039 17.4 0.0 0.0053 17.0 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.1 KOS21522.1 - 0.0042 16.6 0.1 0.0052 16.3 0.1 1.2 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 KOS21522.1 - 0.005 16.7 0.0 0.0058 16.5 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_19 PF13245.1 KOS21522.1 - 0.006 16.3 0.1 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 KOS21522.1 - 0.0062 16.0 0.1 0.076 12.4 0.0 1.9 1 1 1 2 2 2 1 AAA-like domain UPF0079 PF02367.12 KOS21522.1 - 0.011 15.3 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IPT PF01745.11 KOS21522.1 - 0.015 14.5 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Isopentenyl transferase Guanylate_kin PF00625.16 KOS21522.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.3 1 1 0 1 1 1 0 Guanylate kinase AAA_3 PF07726.6 KOS21522.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 KOS21522.1 - 0.02 14.3 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 KOS21522.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase Parvo_NS1 PF01057.12 KOS21522.1 - 0.028 13.2 0.0 0.039 12.8 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CPT PF07931.7 KOS21522.1 - 0.031 13.8 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.4 KOS21522.1 - 0.036 13.5 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.11 KOS21522.1 - 0.04 13.1 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein KTI12 PF08433.5 KOS21522.1 - 0.057 12.6 0.0 0.06 12.5 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NB-ARC PF00931.17 KOS21522.1 - 0.064 12.1 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.13 KOS21522.1 - 0.08 12.4 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 KOS21522.1 - 0.081 11.8 0.2 1.6 7.6 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain DUF815 PF05673.8 KOS21522.1 - 0.098 11.5 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SRPRB PF09439.5 KOS21522.1 - 0.14 11.3 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ran_BP1 PF00638.13 KOS21524.1 - 5.3e-13 49.0 0.1 2.2e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 RanBP1 domain Yip1 PF04893.12 KOS21525.1 - 1.5e-13 50.5 12.5 2.2e-13 50.0 8.6 1.4 1 0 0 1 1 1 1 Yip1 domain 7TM_transglut PF14402.1 KOS21525.1 - 0.12 11.3 7.1 0.16 10.8 4.9 1.1 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase DUF1282 PF06930.7 KOS21525.1 - 0.76 9.4 11.7 1.6 8.3 8.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) PQ-loop PF04193.9 KOS21526.1 - 3.3e-23 80.9 2.2 3.5e-13 48.8 0.1 2.4 2 0 0 2 2 2 2 PQ loop repeat DUF1656 PF07869.7 KOS21528.1 - 0.17 11.6 1.7 0.34 10.7 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) CENP-T PF15511.1 KOS21528.1 - 6.4 5.9 32.8 0.34 10.1 17.6 2.2 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Bromodomain PF00439.20 KOS21529.1 - 4.7e-26 90.5 0.4 8.8e-26 89.6 0.3 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KOS21529.1 - 2.1e-09 37.3 0.1 4.5e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS21529.1 - 4.2e-09 36.2 0.0 1.2e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family NAPRTase PF04095.11 KOS21530.1 - 4.1e-46 157.2 0.0 6.6e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family WD40 PF00400.27 KOS21531.1 - 4.2e-09 35.9 5.4 0.018 14.9 0.0 7.1 5 2 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.1 KOS21531.1 - 1e-07 31.6 3.1 1.3e-06 28.1 1.9 2.7 1 1 0 1 1 1 1 PQQ-like domain CtnDOT_TraJ PF07863.6 KOS21531.1 - 3.9 8.0 7.0 2.8 8.4 0.0 3.5 3 0 0 3 3 3 0 Homologues of TraJ from Bacteroides conjugative transposon Rad4 PF03835.10 KOS21532.1 - 7e-15 54.6 3.0 1.4e-14 53.7 2.1 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 KOS21532.1 - 3e-10 40.2 3.2 8.3e-10 38.8 2.2 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily IBR PF01485.16 KOS21533.1 - 0.1 12.4 2.7 0.3 10.9 2.0 1.7 1 1 0 1 1 1 0 IBR domain C6_DPF PF10170.4 KOS21533.1 - 0.31 11.1 3.3 0.61 10.1 2.3 1.4 1 0 0 1 1 1 0 Cysteine-rich domain FYVE_2 PF02318.11 KOS21533.1 - 0.31 10.9 2.0 0.6 10.0 1.4 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Rad1 PF02144.11 KOS21534.1 - 1.2e-80 270.1 0.0 1.5e-80 269.9 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 WYL PF13280.1 KOS21535.1 - 0.088 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 WYL domain BAR PF03114.13 KOS21536.1 - 3e-64 216.6 5.5 3.7e-64 216.4 3.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KOS21536.1 - 2.4e-15 55.6 0.0 5.3e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KOS21536.1 - 2.7e-12 46.0 0.0 5.5e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KOS21536.1 - 2.9e-08 33.0 0.1 9.1e-08 31.4 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain AHS1 PF02682.11 KOS21536.1 - 0.22 10.9 1.0 0.45 9.9 0.1 1.9 3 0 0 3 3 3 0 Allophanate hydrolase subunit 1 TarH PF02203.10 KOS21536.1 - 0.22 11.3 1.2 2.6 7.8 0.1 2.2 2 0 0 2 2 2 0 Tar ligand binding domain homologue Vps5 PF09325.5 KOS21536.1 - 0.74 9.0 9.3 15 4.7 6.4 2.1 1 1 0 1 1 1 0 Vps5 C terminal like Aminotran_5 PF00266.14 KOS21537.1 - 2.1e-94 316.3 0.0 2.5e-94 316.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KOS21537.1 - 4.2e-07 29.4 0.0 6.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KOS21537.1 - 2.6e-06 26.7 0.0 1.5e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 KOS21537.1 - 0.0087 14.5 0.0 0.012 14.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 KOS21537.1 - 0.026 12.8 0.0 0.038 12.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme F-box-like PF12937.2 KOS21540.1 - 2e-10 40.2 0.3 4e-10 39.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS21540.1 - 1.1e-07 31.3 0.3 2.3e-07 30.2 0.2 1.5 1 0 0 1 1 1 1 F-box domain DUF2183 PF09949.4 KOS21540.1 - 0.16 11.9 0.0 0.58 10.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) F-box-like_2 PF13013.1 KOS21540.1 - 0.16 11.6 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain UIM PF02809.15 KOS21540.1 - 0.2 11.3 18.8 0.092 12.3 2.9 3.3 3 0 0 3 3 3 0 Ubiquitin interaction motif Clr2 PF10383.4 KOS21542.1 - 1.8e-06 28.0 0.0 5.6e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 FYVE_2 PF02318.11 KOS21543.1 - 0.37 10.7 21.5 2.2 8.1 4.9 3.4 3 1 0 3 3 3 0 FYVE-type zinc finger Baculo_PEP_C PF04513.7 KOS21544.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SMC_Nse1 PF07574.8 KOS21545.1 - 2.7e-34 118.5 0.0 3.5e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 KOS21545.1 - 9.2e-14 51.1 8.9 1.5e-13 50.4 6.2 1.4 1 0 0 1 1 1 1 RING-like domain zf-HC5HC2H PF13771.1 KOS21545.1 - 1.2 9.3 5.2 3.4 7.8 3.6 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.1 KOS21545.1 - 2.1 8.2 6.4 3.9 7.3 4.4 1.5 1 0 0 1 1 1 0 Ring finger domain SPRY PF00622.23 KOS21547.1 - 3.7e-08 33.5 0.1 3.7e-07 30.2 0.0 2.5 3 0 0 3 3 3 1 SPRY domain Trehalase PF01204.13 KOS21548.1 - 1.7e-188 627.4 0.0 2.1e-188 627.1 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KOS21548.1 - 2.9e-17 61.6 0.4 5.3e-17 60.8 0.3 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Yippee-Mis18 PF03226.9 KOS21549.1 - 7e-18 64.4 0.0 1.2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Tetraspannin PF00335.15 KOS21549.1 - 0.018 14.2 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family Shisa PF13908.1 KOS21549.1 - 0.032 14.4 0.4 0.053 13.7 0.3 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RIG-I_C-RD PF11648.3 KOS21549.1 - 0.058 13.2 0.2 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I DUF929 PF06053.6 KOS21549.1 - 0.062 12.3 1.5 0.088 11.8 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) ABC2_membrane_2 PF12679.2 KOS21549.1 - 2.1 7.1 5.3 3.1 6.5 3.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1510 PF07423.6 KOS21549.1 - 2.3 7.5 7.1 2.5 7.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Bul1_C PF04426.7 KOS21550.1 - 1e-10 41.2 1.7 4.8e-09 35.8 0.4 2.2 2 0 0 2 2 2 1 Bul1 C terminus Arrestin_N PF00339.24 KOS21550.1 - 5.5e-06 26.2 0.0 0.00015 21.6 0.0 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.7 KOS21550.1 - 5.1e-05 22.0 9.8 0.0031 16.1 0.3 3.6 3 1 1 4 4 4 2 Bul1 N terminus Period_C PF12114.3 KOS21550.1 - 0.00043 19.9 10.0 0.00043 19.9 7.0 1.6 2 0 0 2 2 2 1 Period protein 2/3C-terminal region Arrestin_C PF02752.17 KOS21550.1 - 0.012 15.6 1.4 0.053 13.6 0.1 2.5 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Peptidase_S49_N PF08496.5 KOS21550.1 - 0.14 11.9 0.2 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CAF-1_p150 PF11600.3 KOS21550.1 - 1.9 7.8 17.2 3.4 6.9 11.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TATR PF03430.8 KOS21550.1 - 4 5.9 5.3 5.7 5.4 3.6 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Pyridoxal_deC PF00282.14 KOS21551.1 - 7.5e-108 360.2 0.0 1.1e-107 359.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain cNMP_binding PF00027.24 KOS21552.1 - 2.1e-40 136.4 0.4 1.7e-17 63.0 0.0 5.3 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Patatin PF01734.17 KOS21552.1 - 8.7e-17 61.7 6.9 1.2e-15 57.9 3.4 3.2 2 1 0 2 2 2 1 Patatin-like phospholipase ATP_bind_1 PF03029.12 KOS21553.1 - 1.4e-73 247.3 0.0 2.4e-73 246.6 0.0 1.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KOS21553.1 - 0.0024 16.6 0.0 0.0041 15.9 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_29 PF13555.1 KOS21553.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KOS21553.1 - 0.044 12.8 0.2 0.24 10.4 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 KOS21553.1 - 0.59 10.9 4.1 0.65 10.8 0.2 2.7 1 1 1 3 3 3 0 AAA domain RNase_P_Rpp14 PF01900.14 KOS21554.1 - 6.5e-34 116.0 0.0 8.9e-34 115.6 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family DDDD PF10161.4 KOS21554.1 - 0.16 11.6 1.3 0.36 10.5 0.9 1.5 1 0 0 1 1 1 0 Putative mitochondrial precursor protein MoCF_biosynth PF00994.19 KOS21555.1 - 3.5e-56 188.5 0.9 1.1e-28 99.4 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KOS21555.1 - 1.3e-35 122.1 3.3 2e-35 121.5 2.3 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KOS21555.1 - 2.5e-14 52.9 0.1 7.6e-14 51.4 0.1 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) ATP-synt_C PF00137.16 KOS21556.1 - 1.5e-25 88.8 29.7 8.6e-18 64.0 4.6 3.1 3 1 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 KOS21556.1 - 2.9 7.5 10.5 0.89 9.1 2.9 2.9 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L TFIIA_gamma_C PF02751.9 KOS21557.1 - 6.4e-27 93.1 1.5 8.5e-27 92.7 1.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KOS21557.1 - 1.2e-24 85.6 0.2 1.6e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain EamA PF00892.15 KOS21558.1 - 8.4e-05 22.6 12.1 0.00052 20.0 8.9 1.8 1 1 1 2 2 2 1 EamA-like transporter family UPF0546 PF10639.4 KOS21558.1 - 0.00036 20.3 1.0 0.00046 19.9 0.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 Peptidase_U4 PF03419.8 KOS21558.1 - 0.083 11.9 1.5 0.1 11.6 1.1 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF2029 PF09594.5 KOS21558.1 - 0.088 12.2 11.5 0.022 14.2 4.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2029) EmrE PF13536.1 KOS21558.1 - 3.1 8.0 10.1 5.2 7.3 7.0 1.5 1 1 0 1 1 1 0 Multidrug resistance efflux transporter Voltage_CLC PF00654.15 KOS21559.1 - 2.3e-89 299.8 30.4 2.3e-89 299.8 21.0 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KOS21559.1 - 2.5e-12 46.3 0.1 1.6e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain Abhydrolase_5 PF12695.2 KOS21560.1 - 1e-07 31.8 0.0 1.8e-07 31.0 0.0 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS21560.1 - 0.0037 17.1 4.8 0.28 11.0 2.2 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KOS21560.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 KOS21560.1 - 0.13 10.6 0.0 0.24 9.8 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) WW PF00397.21 KOS21560.1 - 0.18 11.6 1.5 2.6 7.9 0.0 2.8 3 0 0 3 3 3 0 WW domain DAO PF01266.19 KOS21561.1 - 1.4e-51 175.5 3.4 1.8e-51 175.1 2.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KOS21561.1 - 0.00018 21.4 0.0 0.00047 20.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KOS21561.1 - 0.00044 20.3 0.0 0.75 9.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KOS21561.1 - 0.0018 16.8 0.2 0.05 12.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KOS21561.1 - 0.0032 16.3 1.8 0.011 14.6 1.2 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KOS21561.1 - 0.0046 16.8 0.1 0.008 16.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KOS21561.1 - 0.0053 15.8 0.1 0.0081 15.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KOS21561.1 - 0.0085 15.2 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KOS21561.1 - 0.013 15.2 0.3 3.1 7.5 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_4 PF07993.7 KOS21562.1 - 1.1e-34 119.4 0.0 1.1e-32 112.9 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KOS21562.1 - 2.3e-19 69.7 0.0 3.2e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KOS21562.1 - 5e-13 49.1 0.0 1.1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KOS21562.1 - 6.4e-06 25.0 0.0 9.3e-06 24.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KOS21562.1 - 5.4e-05 23.2 0.0 0.00018 21.5 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding AMP-binding_C PF13193.1 KOS21562.1 - 8.5e-05 23.4 0.1 0.0031 18.4 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 KOS21562.1 - 0.0024 16.3 0.5 0.0041 15.5 0.3 1.3 1 0 0 1 1 1 1 AMP-binding enzyme adh_short PF00106.20 KOS21562.1 - 0.006 16.5 0.5 0.034 14.0 0.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase RRP7 PF12923.2 KOS21563.1 - 4.1e-31 107.7 11.6 4.1e-31 107.7 8.1 1.7 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Ribosomal_L14e PF01929.12 KOS21563.1 - 0.016 15.5 3.8 0.016 15.5 2.7 2.0 2 0 0 2 2 2 0 Ribosomal protein L14 Adenylsucc_synt PF00709.16 KOS21564.1 - 3.9e-131 437.5 0.0 5.6e-130 433.7 0.0 1.9 1 1 0 1 1 1 1 Adenylosuccinate synthetase DUF92 PF01940.11 KOS21566.1 - 5.7e-66 221.8 3.9 8.1e-66 221.3 2.7 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 ADIP PF11559.3 KOS21567.1 - 6.3e-35 120.3 5.0 6.3e-35 120.3 3.5 2.5 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 KOS21567.1 - 0.68 9.6 17.2 0.16 11.7 7.2 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 KOS21567.1 - 6.5 6.2 9.8 1.2 8.7 2.7 2.3 2 0 0 2 2 2 0 IncA protein DEAD PF00270.24 KOS21568.1 - 2.1e-31 108.6 0.0 7e-31 106.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS21568.1 - 6.5e-23 80.3 0.5 1.6e-22 79.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KOS21568.1 - 0.00045 19.9 0.1 0.02 14.6 0.0 2.8 2 1 1 3 3 3 1 Part of AAA domain Helicase_C_2 PF13307.1 KOS21568.1 - 0.0065 16.4 0.0 0.022 14.7 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain AAA_22 PF13401.1 KOS21568.1 - 0.041 14.0 0.1 0.51 10.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain CMS1 PF14617.1 KOS21568.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Snf7 PF03357.16 KOS21570.1 - 4.9e-32 110.6 19.3 4.9e-32 110.6 13.3 2.0 1 1 1 2 2 2 1 Snf7 CK2S PF15011.1 KOS21570.1 - 0.018 14.8 1.6 0.032 14.0 0.8 1.6 1 1 0 1 1 1 0 Casein Kinase 2 substrate Allexi_40kDa PF05549.6 KOS21570.1 - 0.05 12.8 5.6 0.069 12.4 3.6 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF3138 PF11336.3 KOS21570.1 - 0.57 8.2 7.4 0.38 8.8 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) MtrB PF05440.7 KOS21570.1 - 0.66 10.0 2.8 1.2 9.2 0.3 2.5 2 1 2 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF2937 PF11157.3 KOS21570.1 - 1 8.6 5.5 1.4 8.2 2.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) zf-C4H2 PF10146.4 KOS21570.1 - 1.1 9.1 16.6 1.7 8.6 11.5 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein DUF4407 PF14362.1 KOS21570.1 - 2.4 7.0 16.2 1.2 7.9 6.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MutS_III PF05192.13 KOS21570.1 - 2.8 7.6 7.4 2.6 7.7 4.5 1.4 1 1 0 1 1 1 0 MutS domain III Syntaxin-6_N PF09177.6 KOS21570.1 - 3.9 7.9 8.0 1.5 9.2 2.3 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cauli_DNA-bind PF03310.8 KOS21570.1 - 5.5 6.8 8.9 1.2 8.9 2.0 2.3 1 1 2 3 3 3 0 Caulimovirus DNA-binding protein HhH-GPD PF00730.20 KOS21571.1 - 1.8e-15 57.1 0.0 3.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4473 PF14747.1 KOS21571.1 - 0.16 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) LRR_5 PF13306.1 KOS21572.1 - 0.01 15.5 5.0 0.023 14.3 0.0 2.5 2 1 0 2 2 2 0 Leucine rich repeats (6 copies) Sugar_tr PF00083.19 KOS21573.1 - 3.2e-125 418.2 20.3 3.6e-125 418.0 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS21573.1 - 4.6e-24 84.7 31.6 3.7e-19 68.6 6.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_2 PF00890.19 KOS21574.1 - 2.1e-84 283.7 0.6 2.6e-84 283.4 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KOS21574.1 - 6.2e-21 73.9 0.2 3.4e-19 68.3 0.0 3.1 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KOS21574.1 - 8.6e-13 47.9 1.1 3.1e-12 46.0 0.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KOS21574.1 - 4.7e-11 42.4 0.3 1.9e-10 40.4 0.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KOS21574.1 - 2.8e-09 37.1 0.0 2.2e-07 30.9 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS21574.1 - 2.5e-08 33.8 3.1 1.4e-07 31.4 0.4 3.1 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KOS21574.1 - 2.8e-06 26.0 2.3 0.0045 15.5 0.3 3.3 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.14 KOS21574.1 - 8.1e-05 21.8 1.7 0.00027 20.1 1.2 1.8 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KOS21574.1 - 0.00015 20.9 0.9 0.016 14.3 0.2 2.5 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 KOS21574.1 - 0.00021 20.2 2.6 0.015 14.1 0.6 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 KOS21574.1 - 0.00056 19.0 0.5 0.65 8.9 0.1 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KOS21574.1 - 0.021 14.6 0.4 0.15 11.7 0.2 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KOS21574.1 - 0.055 13.5 0.1 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS21574.1 - 0.11 12.9 2.5 1.5 9.2 0.4 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CPSF_A PF03178.10 KOS21575.1 - 6.5e-69 232.4 0.0 2.2e-68 230.7 0.0 1.9 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 KOS21575.1 - 0.026 12.6 0.0 0.046 11.8 0.0 1.3 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Pal1 PF08316.6 KOS21576.1 - 1.3e-06 28.8 0.1 2.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Pal1 cell morphology protein DUF605 PF04652.11 KOS21576.1 - 4.3 6.6 9.6 5.7 6.2 6.6 1.2 1 0 0 1 1 1 0 Vta1 like DUF761 PF05553.6 KOS21577.1 - 0.00015 21.0 3.1 0.00033 19.9 2.2 1.5 1 0 0 1 1 1 1 Cotton fibre expressed protein zf-MYND PF01753.13 KOS21577.1 - 0.2 11.5 3.8 0.41 10.5 2.7 1.5 1 0 0 1 1 1 0 MYND finger zf-HIT PF04438.11 KOS21577.1 - 0.29 10.8 4.1 0.66 9.6 2.8 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-C3HC4_2 PF13923.1 KOS21577.1 - 0.48 10.4 5.3 0.95 9.5 3.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Opy2 PF09463.5 KOS21577.1 - 5.7 7.1 14.1 0.21 11.7 4.1 2.5 2 0 0 2 2 2 0 Opy2 protein LMBR1 PF04791.11 KOS21578.1 - 1.9e-13 49.8 17.3 1e-12 47.4 6.3 2.4 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF3591 PF12157.3 KOS21579.1 - 2e-175 583.6 0.2 2.9e-175 583.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.18 KOS21579.1 - 0.011 15.5 0.9 0.025 14.4 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 KOS21579.1 - 0.024 14.3 0.2 0.066 12.8 0.1 1.8 1 0 0 1 1 1 0 Zinc knuckle SRF-TF PF00319.13 KOS21582.1 - 5.6e-23 79.9 0.1 8.8e-23 79.2 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PP2C PF00481.16 KOS21583.1 - 9.6e-85 284.0 0.0 1.4e-84 283.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KOS21583.1 - 3.9e-05 23.1 0.0 6.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KOS21583.1 - 0.0049 16.5 0.0 0.079 12.6 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PPR_2 PF13041.1 KOS21584.1 - 2.4e-08 33.7 0.0 0.00021 21.1 0.0 3.3 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 KOS21584.1 - 0.0021 18.1 0.3 0.45 10.9 0.0 4.2 4 0 0 4 4 4 1 Pentatricopeptide repeat domain Methyltransf_16 PF10294.4 KOS21587.1 - 1.4e-26 93.0 1.7 2.1e-23 82.6 0.1 2.1 1 1 1 2 2 2 2 Putative methyltransferase MTS PF05175.9 KOS21587.1 - 0.00052 19.4 0.2 0.00084 18.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KOS21587.1 - 0.12 12.3 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KOS21587.1 - 0.13 12.8 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain He_PIG PF05345.7 KOS21590.1 - 9e-10 38.4 3.1 0.00023 21.1 0.1 2.8 2 1 0 2 2 2 2 Putative Ig domain DUF1712 PF08217.6 KOS21591.1 - 1.1e-10 40.4 0.0 1.8e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) DPBB_1 PF03330.13 KOS21592.1 - 7.5e-06 25.8 0.9 2.7e-05 24.0 0.2 2.3 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF605 PF04652.11 KOS21592.1 - 4.8 6.4 34.3 7.4 5.8 23.7 1.3 1 0 0 1 1 1 0 Vta1 like MCM PF00493.18 KOS21593.1 - 2.2e-104 348.8 0.1 3e-104 348.3 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KOS21593.1 - 9.1e-19 68.1 0.0 1.9e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KOS21593.1 - 9.5e-08 31.4 0.0 1.6e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KOS21593.1 - 0.0023 17.5 0.0 0.0078 15.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KOS21593.1 - 0.0047 16.4 0.0 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 KOS21593.1 - 0.062 13.0 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ras PF00071.17 KOS21594.1 - 1.4e-32 112.2 0.0 3.2e-32 111.1 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KOS21594.1 - 4.9e-07 30.2 0.0 3.7e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Abhydrolase_6 PF12697.2 KOS21594.1 - 0.084 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Oxysterol_BP PF01237.13 KOS21595.1 - 5.6e-109 363.8 0.0 2e-108 362.0 0.0 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 KOS21595.1 - 2.4e-36 123.6 0.1 1.4e-35 121.1 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KOS21595.1 - 0.0026 17.9 0.0 0.0069 16.5 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KOS21595.1 - 0.11 12.7 0.7 0.69 10.1 0.5 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain GOLD_2 PF13897.1 KOS21595.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Glyco_hydro_72 PF03198.9 KOS21596.1 - 1.5e-122 408.5 0.3 2e-122 408.0 0.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KOS21596.1 - 1.1e-05 24.7 0.6 6.7e-05 22.2 0.4 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ODC_AZ PF02100.12 KOS21597.1 - 3.6e-26 90.7 0.0 4.5e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Tbf5 PF06331.7 KOS21598.1 - 5.8e-28 96.4 1.0 6.3e-28 96.3 0.7 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 TFIIIC_sub6 PF10419.4 KOS21599.1 - 4.7e-13 48.3 0.0 8.9e-13 47.4 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit His_biosynth PF00977.16 KOS21600.1 - 8e-45 152.8 0.0 3.6e-44 150.7 0.0 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KOS21600.1 - 1.6e-25 89.6 0.0 2.8e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 KOS21600.1 - 2.8e-07 30.2 0.0 5.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 KOS21600.1 - 9.3e-07 28.6 0.0 5.7e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family Dus PF01207.12 KOS21600.1 - 0.01 14.7 0.0 0.041 12.6 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.8 KOS21600.1 - 0.014 14.8 0.1 0.073 12.5 0.0 2.0 1 1 0 1 1 1 0 Peptidase C26 GST_C_3 PF14497.1 KOS21601.1 - 0.005 17.2 0.1 0.0072 16.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2731 PF10806.3 KOS21601.1 - 0.083 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2731) GST_C_2 PF13410.1 KOS21601.1 - 0.19 11.6 7.0 0.34 10.8 4.8 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CLTH PF10607.4 KOS21602.1 - 3.8e-32 110.9 0.1 8e-32 109.9 0.1 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KOS21602.1 - 1.2e-15 57.7 0.3 4.7e-15 55.7 0.2 1.8 1 1 0 1 1 1 1 SPRY domain LisH PF08513.6 KOS21602.1 - 2.4e-05 23.9 0.1 9.6e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 LisH DUF387 PF04079.11 KOS21602.1 - 0.05 12.9 0.1 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) PigN PF04987.9 KOS21603.1 - 1.4e-68 231.6 7.1 1.8e-68 231.2 4.9 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) DUF2721 PF11026.3 KOS21603.1 - 7.7 6.1 9.5 0.25 10.9 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Peptidase_M1 PF01433.15 KOS21604.1 - 2.4e-07 30.1 11.0 0.029 13.4 0.0 3.5 4 0 0 4 4 4 3 Peptidase family M1 HEAT_2 PF13646.1 KOS21604.1 - 0.00076 19.7 0.1 0.65 10.3 0.0 3.6 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 KOS21604.1 - 0.032 14.2 0.3 17 5.7 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat BAR_2 PF10455.4 KOS21605.1 - 3.4e-50 170.5 0.0 5e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KOS21605.1 - 1.4e-14 54.1 0.5 2e-13 50.3 0.4 2.0 1 1 0 1 1 1 1 BAR domain DUF488 PF04343.8 KOS21605.1 - 0.0082 16.5 0.4 0.04 14.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF488 Podoplanin PF05808.6 KOS21607.1 - 2.4 7.6 9.0 0.2 11.1 0.2 2.9 2 1 0 2 2 2 0 Podoplanin MFS_1 PF07690.11 KOS21608.1 - 0.00013 20.8 38.1 0.086 11.5 0.1 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily IncA PF04156.9 KOS21608.1 - 0.061 12.9 0.1 0.061 12.9 0.0 2.8 3 0 0 3 3 3 0 IncA protein Pkinase PF00069.20 KOS21610.1 - 2.4e-57 194.0 0.0 3.3e-57 193.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS21610.1 - 1.3e-20 73.6 0.3 3.5e-20 72.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KOS21610.1 - 0.033 13.9 0.0 0.13 11.9 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KOS21610.1 - 0.11 12.1 0.3 0.2 11.1 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pex24p PF06398.6 KOS21611.1 - 2.9e-86 289.5 0.0 7.1e-86 288.2 0.0 1.6 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Reticulon PF02453.12 KOS21611.1 - 0.0072 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Reticulon polyprenyl_synt PF00348.12 KOS21612.1 - 3.6e-56 189.8 0.0 4.3e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CDC14 PF08045.6 KOS21613.1 - 1.2e-81 273.6 0.0 3e-81 272.3 0.0 1.6 1 1 0 1 1 1 1 Cell division control protein 14, SIN component DUF3246 PF11596.3 KOS21613.1 - 0.17 11.1 1.2 0.25 10.5 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) IDO PF01231.13 KOS21615.1 - 4.2e-37 127.6 0.0 2.1e-18 65.9 0.0 2.1 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase INO80_Ies4 PF08193.6 KOS21616.1 - 2.7e-54 184.5 18.9 3.3e-54 184.2 13.1 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 ER_lumen_recept PF00810.13 KOS21617.1 - 7e-35 120.6 8.9 9.3e-35 120.2 6.2 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor HlyIII PF03006.15 KOS21617.1 - 0.071 12.5 8.5 0.84 9.0 0.2 2.1 2 0 0 2 2 2 0 Haemolysin-III related PQ-loop PF04193.9 KOS21617.1 - 0.12 11.9 4.1 0.13 11.7 0.0 3.0 3 0 0 3 3 3 0 PQ loop repeat DUF4181 PF13789.1 KOS21617.1 - 0.13 12.1 2.4 0.27 11.1 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) LicD PF04991.8 KOS21618.1 - 3.4e-22 79.5 6.4 5e-17 62.6 0.1 3.0 2 1 0 2 2 2 2 LicD family LETM1 PF07766.8 KOS21619.1 - 1.3e-103 345.6 0.1 2.1e-103 345.0 0.1 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 KOS21619.1 - 0.0004 19.8 0.0 0.15 11.5 0.0 2.7 3 0 0 3 3 3 2 SAP domain ADK PF00406.17 KOS21620.1 - 6e-34 117.1 0.0 5e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 KOS21620.1 - 2.3e-13 49.5 0.0 3.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 KOS21620.1 - 6.5e-05 23.2 0.0 0.00072 19.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KOS21620.1 - 0.00013 22.8 0.0 0.0011 19.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS21620.1 - 0.0065 16.3 0.1 0.028 14.3 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KOS21620.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Peptidase_S8 PF00082.17 KOS21621.1 - 1.9e-55 187.9 0.3 2.9e-55 187.4 0.2 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KOS21621.1 - 5.1e-30 103.1 0.7 1.1e-29 102.0 0.5 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF605 PF04652.11 KOS21621.1 - 2.7 7.2 9.6 4.6 6.5 6.6 1.3 1 0 0 1 1 1 0 Vta1 like PX PF00787.19 KOS21622.1 - 6.9e-19 67.7 1.6 8.8e-19 67.3 0.3 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KOS21622.1 - 6.5e-09 35.3 6.2 0.00014 21.2 0.4 2.3 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 KOS21622.1 - 7.3e-05 22.3 3.1 0.00018 21.1 2.2 1.6 1 1 0 1 1 1 1 BAR domain Reo_sigmaC PF04582.7 KOS21622.1 - 0.0033 16.6 0.1 0.0054 15.9 0.1 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF3140 PF11338.3 KOS21622.1 - 0.05 13.7 0.2 0.05 13.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) FlaC_arch PF05377.6 KOS21622.1 - 0.11 12.3 0.3 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3287 PF11690.3 KOS21622.1 - 0.24 11.4 2.2 17 5.5 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) DUF1664 PF07889.7 KOS21622.1 - 0.32 10.7 2.6 11 5.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) eIF3_subunit PF08597.5 KOS21622.1 - 0.63 9.5 7.5 0.38 10.2 1.5 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit GreA_GreB_N PF03449.10 KOS21622.1 - 1.9 8.5 6.6 0.62 10.1 1.1 2.5 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Occludin_ELL PF07303.8 KOS21622.1 - 2.2 9.0 7.0 5 7.9 0.1 3.7 4 1 0 4 4 4 0 Occludin homology domain bZIP_2 PF07716.10 KOS21622.1 - 3.7 7.4 11.9 0.36 10.6 1.2 3.0 3 0 0 3 3 3 0 Basic region leucine zipper APG6 PF04111.7 KOS21622.1 - 5.8 5.8 6.6 4.9 6.1 0.1 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 TPMT PF05724.6 KOS21624.1 - 8e-30 103.8 0.0 1.1e-28 100.2 0.0 2.2 2 1 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 KOS21624.1 - 7.9e-09 35.4 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS21624.1 - 2.7e-08 33.5 0.0 0.00073 19.1 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KOS21624.1 - 1.2e-07 32.1 0.0 3.8e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS21624.1 - 8.7e-07 29.5 0.0 1.3e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS21624.1 - 2.7e-06 27.7 0.0 4.8e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS21624.1 - 0.0016 18.4 0.0 0.0045 17.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KOS21624.1 - 0.0034 16.5 0.0 0.0067 15.6 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB adh_short_C2 PF13561.1 KOS21625.1 - 8.7e-26 91.1 0.0 1e-25 90.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KOS21625.1 - 3.1e-19 69.4 1.3 4.3e-19 69.0 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase P12 PF12669.2 KOS21626.1 - 0.11 12.6 1.9 0.18 12.0 1.3 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family Peptidase_S8 PF00082.17 KOS21627.1 - 1.1e-46 159.2 12.4 1.6e-46 158.7 8.6 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KOS21627.1 - 3.7e-05 24.2 0.2 0.00019 21.9 0.1 2.2 2 0 0 2 2 2 1 Peptidase inhibitor I9 LSM PF01423.17 KOS21628.1 - 2.1e-16 59.2 0.0 3.3e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain SpoU_sub_bind PF08032.7 KOS21628.1 - 0.092 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding GRP PF07172.6 KOS21628.1 - 0.97 9.9 19.5 1.2 9.6 13.5 1.2 1 0 0 1 1 1 0 Glycine rich protein family PPR_3 PF13812.1 KOS21629.1 - 6.2e-12 44.8 13.2 0.00025 21.0 0.0 6.9 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 KOS21629.1 - 7.7e-09 35.3 0.0 0.027 14.4 0.0 5.0 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.15 KOS21629.1 - 1.1e-05 25.0 1.5 0.26 11.3 0.0 4.9 5 0 0 5 5 5 2 PPR repeat POX PF07526.6 KOS21629.1 - 0.031 14.5 0.2 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Associated with HOX PPR_1 PF12854.2 KOS21629.1 - 0.05 13.0 0.3 0.65 9.5 0.1 2.8 2 0 0 2 2 2 0 PPR repeat Menin PF05053.8 KOS21629.1 - 3.7 5.6 9.6 0.32 9.1 0.1 2.3 3 0 0 3 3 3 0 Menin Inositol_P PF00459.20 KOS21630.1 - 6.4e-63 212.5 0.0 8.3e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.11 KOS21631.1 - 1e-41 142.8 32.8 1e-41 142.8 22.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS21631.1 - 1.4e-11 43.6 1.1 1.4e-11 43.6 0.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 KOS21631.1 - 0.0019 16.3 0.2 0.0039 15.2 0.1 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 KOS21631.1 - 0.0054 14.9 2.4 0.0054 14.9 1.7 2.2 1 1 1 2 2 2 2 Transmembrane secretion effector PLA2_B PF01735.13 KOS21632.1 - 4e-24 84.6 0.0 2.9e-23 81.8 0.0 1.9 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Baculo_FP PF03258.9 KOS21632.1 - 0.12 11.4 0.1 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Baculovirus FP protein Rhodanese PF00581.15 KOS21633.1 - 2.7e-13 50.2 0.0 3.7e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain HET PF06985.6 KOS21634.1 - 3.1e-18 66.2 7.2 3.3e-16 59.7 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) S4 PF01479.20 KOS21635.1 - 2.7e-13 49.1 0.1 5.4e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 S4 domain BCDHK_Adom3 PF10436.4 KOS21636.1 - 6.7e-42 142.7 0.0 8.7e-42 142.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KOS21636.1 - 2.2e-17 62.7 0.0 6.9e-16 57.9 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KOS21636.1 - 0.022 14.4 0.0 0.053 13.1 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KOS21636.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Inhibitor_I9 PF05922.11 KOS21637.1 - 2.5e-09 37.5 0.1 3e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 Chitin_synth_2 PF03142.10 KOS21638.1 - 1.5e-253 841.9 0.5 2.2e-253 841.4 0.4 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KOS21638.1 - 4.9e-157 523.9 0.0 6.6e-157 523.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 KOS21638.1 - 3.3e-18 65.1 0.4 3.3e-17 61.9 0.5 2.3 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 KOS21638.1 - 8.5e-17 60.7 0.2 1e-09 38.0 0.0 3.2 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 KOS21638.1 - 2.9e-15 56.6 0.1 2.1e-11 44.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KOS21638.1 - 7.1e-15 55.2 2.9 7.1e-15 55.2 2.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KOS21638.1 - 3.4e-05 23.5 0.0 0.0054 16.4 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 MMR_HSR1 PF01926.18 KOS21638.1 - 0.0034 17.3 0.3 3.6 7.5 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KOS21638.1 - 0.0048 16.9 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KOS21638.1 - 0.0049 16.0 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 KOS21638.1 - 0.005 17.1 0.5 0.031 14.5 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 KOS21638.1 - 0.0085 16.2 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Glyco_transf_21 PF13506.1 KOS21638.1 - 0.012 14.8 0.2 0.11 11.7 0.2 2.4 2 1 0 2 2 2 0 Glycosyl transferase family 21 DUF2592 PF10766.4 KOS21638.1 - 0.12 11.7 2.2 0.32 10.3 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) Chitin_synth_2 PF03142.10 KOS21639.1 - 2.2e-226 752.3 0.0 2.8e-226 751.9 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KOS21639.1 - 1.2e-50 172.3 0.0 3.7e-41 140.9 0.0 2.6 2 1 0 2 2 2 2 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 KOS21639.1 - 1.4e-18 67.3 3.9 1.4e-18 67.3 2.7 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KOS21639.1 - 6.1e-17 62.1 0.0 3.1e-14 53.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 KOS21639.1 - 5.5e-14 51.6 1.5 5.6e-13 48.4 0.8 2.4 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 KOS21639.1 - 1.2e-11 44.2 0.0 1.3e-05 24.8 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 KOS21639.1 - 7.7e-06 25.3 0.0 3.1e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KOS21639.1 - 0.00054 19.6 0.0 0.036 13.7 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.1 KOS21639.1 - 0.024 14.9 0.2 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 Na_Ca_ex PF01699.19 KOS21640.1 - 1.4e-19 70.1 13.6 2.4e-17 62.8 3.6 2.4 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF3566 PF12089.3 KOS21640.1 - 0.002 18.1 4.6 0.0026 17.7 1.4 2.3 1 1 1 2 2 2 1 Transmembrane domain of unknown function (DUF3566) Herpes_LMP1 PF05297.6 KOS21640.1 - 0.24 10.3 1.9 0.38 9.6 1.3 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) MFS_1 PF07690.11 KOS21640.1 - 0.93 8.1 10.9 0.37 9.4 0.3 2.4 1 1 0 2 2 2 0 Major Facilitator Superfamily Chitin_synth_2 PF03142.10 KOS21641.1 - 3.9e-25 88.2 3.3 6e-23 81.0 1.1 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 KOS21641.1 - 9.4e-17 61.5 0.0 1.8e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KOS21641.1 - 4.9e-16 59.0 7.5 4.9e-16 59.0 5.2 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KOS21641.1 - 0.0063 16.2 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Calpain_III PF01067.17 KOS21641.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Calpain large subunit, domain III Autophagy_act_C PF03987.10 KOS21641.1 - 0.13 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Autophagocytosis associated protein, active-site domain Abhydrolase_5 PF12695.2 KOS21642.1 - 4.3e-14 52.4 0.1 7.3e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS21642.1 - 4.8e-14 52.7 0.6 6.8e-14 52.2 0.1 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS21642.1 - 2.4e-08 33.8 0.0 3.3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KOS21642.1 - 3.6e-07 29.9 0.1 5.1e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 KOS21642.1 - 4.2e-05 23.0 0.0 5.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 KOS21642.1 - 7.6e-05 22.4 0.4 0.00028 20.6 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KOS21642.1 - 0.004 16.4 0.0 0.0071 15.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Tmemb_9 PF05434.6 KOS21642.1 - 0.15 11.8 0.7 0.31 10.7 0.5 1.5 1 0 0 1 1 1 0 TMEM9 NMT_C PF02799.10 KOS21643.1 - 9.3e-72 240.4 0.1 1.6e-71 239.6 0.1 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 KOS21643.1 - 4.3e-71 237.7 0.0 8.4e-71 236.8 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 KOS21643.1 - 5.3e-05 23.0 0.1 0.00046 20.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS21643.1 - 0.057 13.4 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS21643.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SPT6_acidic PF14632.1 KOS21643.1 - 0.4 10.8 4.1 1.2 9.3 2.7 1.9 2 0 0 2 2 2 0 Acidic N-terminal SPT6 PX PF00787.19 KOS21644.1 - 2e-21 75.8 0.0 3.4e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 PX domain AF-4 PF05110.8 KOS21646.1 - 0.029 12.2 23.6 0.035 11.9 16.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RAP1 PF07218.6 KOS21646.1 - 0.18 9.8 19.3 0.21 9.6 13.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDC45 PF02724.9 KOS21646.1 - 0.24 9.3 12.9 0.28 9.1 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Utp14 PF04615.8 KOS21646.1 - 0.64 8.1 18.8 0.75 7.8 13.0 1.0 1 0 0 1 1 1 0 Utp14 protein Menin PF05053.8 KOS21646.1 - 0.77 7.8 14.3 0.89 7.6 9.9 1.1 1 0 0 1 1 1 0 Menin DUF605 PF04652.11 KOS21646.1 - 0.81 9.0 19.8 0.98 8.7 13.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF1510 PF07423.6 KOS21646.1 - 0.84 8.9 14.3 1.2 8.4 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TFIIA PF03153.8 KOS21646.1 - 1.1 9.0 16.5 1.4 8.7 11.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.11 KOS21646.1 - 1.4 8.7 11.2 1.7 8.4 7.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop25 PF09805.4 KOS21646.1 - 1.4 8.9 7.0 1.8 8.6 4.8 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Macoilin PF09726.4 KOS21646.1 - 1.7 6.8 29.0 2 6.5 20.1 1.1 1 0 0 1 1 1 0 Transmembrane protein PAP1 PF08601.5 KOS21646.1 - 1.7 8.2 32.3 2.2 7.9 22.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Apt1 PF10351.4 KOS21646.1 - 2.1 7.1 20.5 2.4 6.8 14.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.2 KOS21646.1 - 2.5 5.6 26.5 2.8 5.5 18.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.8 KOS21646.1 - 4.8 5.6 19.5 5.9 5.3 13.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MIP-T3 PF10243.4 KOS21646.1 - 5.7 5.2 18.2 6 5.2 12.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2217 PF10265.4 KOS21646.1 - 7.8 5.1 16.0 9 4.9 11.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Raftlin PF15250.1 KOS21646.1 - 8.8 4.7 15.7 10 4.4 10.9 1.1 1 0 0 1 1 1 0 Raftlin SAS4 PF15460.1 KOS21647.1 - 1.6e-33 114.6 0.0 5.4e-33 112.8 0.0 2.0 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Nop14 PF04147.7 KOS21647.1 - 3 5.6 26.9 4.7 5.0 18.7 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KOS21647.1 - 3.8 7.0 13.9 0.018 14.5 2.4 2.1 2 0 0 2 2 2 0 Nucleoplasmin Abhydrolase_6 PF12697.2 KOS21648.1 - 2.2e-25 89.8 0.6 3.1e-25 89.4 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS21648.1 - 2.2e-17 63.3 0.0 5.1e-16 58.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS21648.1 - 1.8e-11 43.9 0.0 4.6e-11 42.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.4 KOS21648.1 - 0.00022 20.1 0.0 0.00048 19.1 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Thioesterase PF00975.15 KOS21648.1 - 0.00037 20.8 0.0 0.00069 19.9 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 KOS21648.1 - 0.034 13.5 0.0 0.076 12.4 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Abhydrolase_4 PF08386.5 KOS21648.1 - 0.037 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_3 PF07859.8 KOS21648.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KOS21648.1 - 0.12 12.2 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 KOS21648.1 - 0.14 11.3 0.0 10 5.2 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KOS21648.1 - 0.16 11.3 0.0 3.8 6.8 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_M28 PF04389.12 KOS21649.1 - 7.9e-37 126.7 0.0 1.2e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Ribophorin_II PF05817.9 KOS21649.1 - 3.8e-19 68.3 0.0 5.6e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II CDP-OH_P_transf PF01066.16 KOS21650.1 - 4.1e-18 65.5 2.8 4.1e-18 65.5 2.0 2.7 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Exo70 PF03081.10 KOS21652.1 - 8.8e-37 126.7 0.0 1.3e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit PfkB PF00294.19 KOS21653.1 - 4.6e-13 48.9 0.0 4.1e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Fungal_trans PF04082.13 KOS21654.1 - 3.5e-27 94.9 0.0 1.3e-26 93.0 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF605 PF04652.11 KOS21654.1 - 0.00054 19.4 8.6 0.012 15.0 0.2 2.2 2 0 0 2 2 2 2 Vta1 like DUF4306 PF14154.1 KOS21654.1 - 0.18 11.7 0.5 0.32 11.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) WSC PF01822.14 KOS21655.1 - 4.2e-17 61.8 5.1 1.1e-16 60.5 3.5 1.7 1 0 0 1 1 1 1 WSC domain Grp1_Fun34_YaaH PF01184.14 KOS21656.1 - 8.6e-83 276.7 19.3 1.1e-82 276.4 13.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Cyt-b5 PF00173.23 KOS21657.1 - 9e-17 60.6 0.0 1.5e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MFS_1 PF07690.11 KOS21659.1 - 3.7e-27 94.9 60.0 6.5e-15 54.6 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KOS21659.1 - 3e-06 25.8 29.9 3.5e-06 25.6 10.0 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein Mito_fiss_reg PF05308.6 KOS21659.1 - 0.73 9.1 8.3 1.2 8.4 5.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator FHA PF00498.21 KOS21660.1 - 1.1e-07 31.9 0.0 2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 KOS21660.1 - 0.0041 17.2 2.0 0.01 15.9 0.0 2.5 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Herpes_DNAp_acc PF04929.7 KOS21660.1 - 0.28 10.1 8.2 0.61 9.0 5.7 1.5 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RNase_H2-Ydr279 PF09468.5 KOS21660.1 - 2.7 7.0 13.3 8.1 5.5 9.2 1.7 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SQS_PSY PF00494.14 KOS21661.1 - 7.1e-41 140.2 0.0 1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase adh_short_C2 PF13561.1 KOS21662.1 - 2.8e-22 79.6 0.0 7.6e-22 78.2 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 KOS21662.1 - 9.8e-21 74.3 0.0 1.9e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 KOS21662.1 - 2.2e-18 66.1 0.0 6.2e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 KOS21662.1 - 7e-11 42.0 0.0 1.8e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KOS21662.1 - 1.8e-06 27.9 0.4 5.8e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KOS21662.1 - 0.00047 19.8 0.0 0.0022 17.6 0.0 2.2 2 0 0 2 2 2 1 KR domain DnaJ-X PF14308.1 KOS21663.1 - 2.6e-70 235.8 0.1 2.6e-70 235.8 0.1 2.5 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 KOS21663.1 - 8.2e-26 89.5 0.5 1.8e-25 88.4 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain PAT1 PF09770.4 KOS21663.1 - 0.0074 14.5 3.6 0.011 14.0 2.5 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.5 KOS21663.1 - 1.3 7.3 2.4 1.8 6.8 1.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RmlD_sub_bind PF04321.12 KOS21664.1 - 8.4e-18 64.2 0.0 1.4e-17 63.5 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KOS21664.1 - 4.2e-14 52.5 0.0 8.2e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KOS21664.1 - 2.2e-07 30.0 0.0 6.1e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KOS21664.1 - 0.0001 22.2 0.4 0.0002 21.3 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KOS21664.1 - 0.0018 18.0 0.1 0.0051 16.4 0.0 1.7 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 KOS21664.1 - 0.059 12.0 0.1 0.19 10.3 0.1 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Acyl_transf_1 PF00698.16 KOS21665.1 - 1.9e-78 263.9 0.0 3e-76 256.8 0.0 3.1 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 KOS21665.1 - 1.3e-37 127.8 0.0 3e-37 126.7 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 KOS21665.1 - 6e-30 102.8 0.4 1.9e-29 101.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 KOS21665.1 - 1.2e-22 80.0 0.0 5.7e-22 77.9 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Ycf1 PF05758.7 KOS21666.1 - 1.9 6.0 17.8 2.6 5.6 12.3 1.1 1 0 0 1 1 1 0 Ycf1 PHD PF00628.24 KOS21667.1 - 4.5 7.0 13.6 2 8.1 1.3 3.2 3 1 0 3 3 3 0 PHD-finger Atg14 PF10186.4 KOS21668.1 - 8.6e-19 67.5 0.2 1.4e-18 66.8 0.1 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 KOS21668.1 - 2.6 6.6 8.5 3.9 6.0 5.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PRTP PF01366.13 KOS21668.1 - 3.6 5.4 5.4 5.6 4.8 3.7 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein NUDIX PF00293.23 KOS21669.1 - 5.3e-16 58.4 0.0 6.4e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain APH PF01636.18 KOS21670.1 - 5e-05 23.1 3.9 0.0066 16.2 0.5 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KOS21670.1 - 5.9e-05 22.2 0.0 0.0016 17.5 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KOS21670.1 - 0.00048 19.3 0.0 0.00054 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KOS21670.1 - 0.066 12.5 0.0 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Aldo_ket_red PF00248.16 KOS21671.1 - 1e-09 37.6 0.0 1.4e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.15 KOS21672.1 - 3.2e-46 156.5 0.2 4.1e-46 156.2 0.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.5 KOS21673.1 - 6.6e-52 175.9 0.0 8.6e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator CsbD PF05532.7 KOS21674.1 - 2.1e-12 46.4 24.6 1.4e-10 40.6 4.2 3.7 3 1 1 4 4 4 3 CsbD-like RRM_1 PF00076.17 KOS21675.1 - 3.2e-13 49.1 0.0 5e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS21675.1 - 1.1e-10 41.3 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS21675.1 - 6.4e-08 32.3 0.0 1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KOS21676.1 - 0.0095 15.7 0.8 35 4.4 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Chitin_synth_2 PF03142.10 KOS21677.1 - 5.8e-41 140.4 0.8 1.4e-33 116.1 0.2 2.3 2 0 0 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.21 KOS21677.1 - 1.4e-10 41.1 0.0 0.00011 21.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 KOS21677.1 - 6.4e-08 32.5 2.0 6.4e-08 32.5 1.4 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KOS21677.1 - 8.9e-05 22.3 0.3 0.083 12.6 0.0 3.0 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Peptidase_M28 PF04389.12 KOS21678.1 - 3.7e-23 82.1 1.0 5.5e-12 45.7 0.0 2.3 1 1 1 2 2 2 2 Peptidase family M28 PA PF02225.17 KOS21678.1 - 1.3e-13 50.4 0.1 3.2e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 KOS21678.1 - 0.008 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 UDPG_MGDP_dh_N PF03721.9 KOS21679.1 - 1.6e-18 66.7 0.1 1.2e-12 47.6 0.0 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 KOS21679.1 - 7e-18 64.6 0.0 1.3e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.10 KOS21679.1 - 0.0028 17.4 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.10 KOS21679.1 - 0.035 14.2 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Methyltransf_18 PF12847.2 KOS21679.1 - 0.064 13.8 0.0 0.67 10.5 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain TrkA_N PF02254.13 KOS21679.1 - 0.068 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 KOS21679.1 - 0.16 10.9 0.0 8.9 5.1 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase Polysacc_deac_1 PF01522.16 KOS21680.1 - 4.2e-27 94.2 0.0 7.2e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Ppx-GppA PF02541.11 KOS21681.1 - 1.6e-35 122.7 0.0 3.4e-35 121.6 0.0 1.6 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Cyclin PF08613.6 KOS21682.1 - 7.1e-38 130.3 0.0 1.4e-37 129.4 0.0 1.4 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KOS21682.1 - 0.022 14.3 0.0 0.022 14.3 0.0 1.7 2 0 0 2 2 2 0 Cyclin, N-terminal domain Fungal_trans PF04082.13 KOS21683.1 - 1.2e-09 37.4 0.1 7.7e-05 21.6 0.0 3.0 2 1 1 3 3 3 3 Fungal specific transcription factor domain MMR_HSR1_C PF08438.5 KOS21685.1 - 1.8e-33 115.0 0.0 3.1e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KOS21685.1 - 1.8e-18 66.6 0.0 4.2e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS21685.1 - 6e-09 35.3 0.1 3.6e-07 29.5 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KOS21685.1 - 0.0008 19.2 0.5 0.1 12.3 0.2 3.0 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 KOS21685.1 - 0.0035 16.7 0.1 0.51 9.7 0.0 3.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KOS21685.1 - 0.082 12.0 0.2 0.44 9.6 0.0 2.0 2 0 0 2 2 2 0 AIG1 family TPR_11 PF13414.1 KOS21686.1 - 0.00029 20.4 2.7 0.15 11.7 0.1 2.9 2 1 0 2 2 2 2 TPR repeat TPR_14 PF13428.1 KOS21686.1 - 0.0057 17.1 4.6 0.17 12.6 1.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KOS21686.1 - 0.0062 17.1 8.1 0.052 14.2 0.9 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat LRR_4 PF12799.2 KOS21686.1 - 0.035 13.7 4.2 2.3 7.9 0.0 4.0 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) TPR_2 PF07719.12 KOS21686.1 - 9.2 6.4 8.7 3.8 7.6 0.3 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Aminotran_4 PF01063.14 KOS21687.1 - 2.3e-20 73.0 0.0 4.5e-20 72.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class IV TPR_11 PF13414.1 KOS21688.1 - 1.2e-53 178.5 40.8 6e-13 48.2 0.2 7.1 3 3 6 9 9 9 9 TPR repeat TPR_1 PF00515.23 KOS21688.1 - 6.2e-42 139.5 19.0 2e-05 23.9 0.1 11.5 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 KOS21688.1 - 1.6e-40 133.7 19.7 8.9e-05 22.1 0.1 11.5 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.1 KOS21688.1 - 1.7e-25 89.0 19.4 3.2e-07 30.8 0.2 6.9 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KOS21688.1 - 8.7e-24 83.2 22.4 2.5e-06 27.3 0.0 7.2 3 2 3 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 KOS21688.1 - 2.3e-20 71.0 10.7 0.0006 19.8 0.0 9.0 10 1 0 10 10 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 KOS21688.1 - 2e-17 61.6 15.1 0.0057 16.3 0.2 9.9 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 KOS21688.1 - 2.7e-14 52.3 17.5 0.0027 18.1 0.1 10.0 3 3 8 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 KOS21688.1 - 3.4e-12 46.5 19.8 0.00037 20.7 0.1 7.0 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 KOS21688.1 - 9.3e-11 41.4 10.3 0.0091 15.8 0.2 7.0 3 2 4 7 7 7 4 Tetratricopeptide repeat Apc3 PF12895.2 KOS21688.1 - 7.1e-10 38.8 12.8 0.011 15.8 0.4 5.4 2 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KOS21688.1 - 5e-08 32.1 19.4 0.026 14.3 0.2 9.1 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.1 KOS21688.1 - 2.7e-06 27.4 20.6 0.11 12.9 0.0 9.0 9 0 0 9 9 9 1 Tetratricopeptide repeat MAS20 PF02064.10 KOS21688.1 - 0.0033 17.3 2.4 9.6 6.1 0.0 4.1 5 0 0 5 5 5 0 MAS20 protein import receptor DUF3856 PF12968.2 KOS21688.1 - 0.036 13.8 9.9 2.1 8.1 0.0 5.5 5 2 1 6 6 6 0 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.4 KOS21688.1 - 0.074 12.3 5.2 23 4.3 0.0 4.9 5 0 0 5 5 5 0 SHNi-TPR DUF3865 PF12981.2 KOS21688.1 - 0.076 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) Syntaxin PF00804.20 KOS21689.1 - 2e-11 43.9 0.6 2e-11 43.9 0.4 2.3 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 KOS21689.1 - 1.3e-09 37.5 4.5 3e-09 36.4 3.1 1.6 1 0 0 1 1 1 1 SNARE domain DUF3094 PF11293.3 KOS21689.1 - 0.0024 17.3 0.1 0.0051 16.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3094) BatA PF07584.6 KOS21689.1 - 0.025 14.7 0.1 0.066 13.4 0.1 1.7 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Allexi_40kDa PF05549.6 KOS21689.1 - 0.044 13.0 4.5 0.067 12.4 0.2 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Use1 PF09753.4 KOS21689.1 - 0.076 12.4 3.4 0.12 11.8 2.3 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF2077 PF09850.4 KOS21689.1 - 0.096 12.0 0.2 0.096 12.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) PBP1_TM PF14812.1 KOS21689.1 - 0.13 12.5 0.1 0.13 12.5 0.1 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Syntaxin_2 PF14523.1 KOS21689.1 - 0.29 11.1 8.6 0.049 13.6 1.8 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF3708 PF12501.3 KOS21689.1 - 0.51 10.1 6.4 0.29 10.9 1.0 2.5 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter Fib_alpha PF08702.5 KOS21689.1 - 3.4 7.7 8.5 5.4 7.1 1.5 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PP-binding PF00550.20 KOS21690.1 - 1.2e-10 41.5 0.1 1.7e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KOS21690.1 - 0.00012 22.0 0.6 0.00022 21.1 0.3 1.3 1 1 0 1 1 1 1 Acyl-carrier zf-CCCH PF00642.19 KOS21691.1 - 7.8e-10 38.2 10.1 3.3e-05 23.4 1.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KOS21691.1 - 7.3 6.7 25.0 0.16 11.9 3.9 3.0 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type DUF2517 PF10725.4 KOS21692.1 - 0.052 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) BTB PF00651.26 KOS21693.1 - 9.5e-05 22.3 0.0 0.00024 21.0 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain IGFBP PF00219.13 KOS21694.1 - 0.25 11.8 0.3 0.25 11.8 0.2 2.4 3 1 0 3 3 3 0 Insulin-like growth factor binding protein MFS_1 PF07690.11 KOS21697.1 - 1.9e-37 128.8 45.8 3.3e-25 88.5 9.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS21697.1 - 3.3e-09 35.8 33.4 2e-05 23.3 7.8 3.2 2 2 1 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.2 KOS21697.1 - 9.7e-05 22.0 1.9 9.7e-05 22.0 1.3 3.6 4 0 0 4 4 4 1 MFS_1 like family DUF3704 PF12488.3 KOS21697.1 - 0.013 15.1 0.3 0.068 12.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) adh_short PF00106.20 KOS21698.1 - 2e-20 73.3 0.4 3.2e-20 72.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS21698.1 - 5.5e-08 32.6 0.3 8e-08 32.1 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KOS21698.1 - 3e-05 23.9 0.0 3.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 2OG-FeII_Oxy PF03171.15 KOS21699.1 - 1.4e-10 41.3 0.0 4.6e-10 39.6 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KOS21699.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal ketoacyl-synt PF00109.21 KOS21700.1 - 3.5e-63 213.4 1.1 9.4e-63 212.0 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KOS21700.1 - 4.9e-62 210.1 0.1 8.9e-62 209.2 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KOS21700.1 - 1.1e-57 195.5 0.7 1.9e-57 194.6 0.1 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.5 KOS21700.1 - 2.6e-39 134.7 0.1 5.8e-39 133.6 0.0 1.6 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.17 KOS21700.1 - 4.2e-37 126.6 0.1 1.2e-36 125.1 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KOS21700.1 - 3.2e-27 95.4 0.5 1e-26 93.8 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Glyoxalase_3 PF13468.1 KOS21700.1 - 1.2e-20 74.0 0.0 2.6e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase-like domain Methyltransf_12 PF08242.7 KOS21700.1 - 3.1e-15 56.4 0.0 8.3e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS21700.1 - 3.3e-10 39.9 0.0 7.2e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS21700.1 - 8e-09 36.0 0.0 5.2e-08 33.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS21700.1 - 1.7e-07 30.9 0.0 3.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS21700.1 - 9.3e-06 26.0 0.0 2.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KOS21700.1 - 3.8e-05 23.8 0.0 0.00013 22.1 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.4 KOS21700.1 - 0.032 13.7 0.0 0.36 10.2 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase CFEM PF05730.6 KOS21701.1 - 4.8e-38 128.8 77.0 3.8e-10 39.4 9.3 4.8 4 0 0 4 4 4 4 CFEM domain Nitro_FeMo-Co PF02579.12 KOS21701.1 - 0.044 13.8 0.0 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor FAD_binding_4 PF01565.18 KOS21702.1 - 2.5e-13 49.6 0.2 4.9e-13 48.7 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KOS21702.1 - 5.8e-09 35.7 0.3 1.2e-08 34.6 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like HATPase_c PF02518.21 KOS21703.1 - 9.5e-28 96.1 0.0 2.1e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KOS21703.1 - 8.1e-23 80.5 0.7 2e-22 79.2 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KOS21703.1 - 2.1e-19 69.2 0.4 8.4e-19 67.3 0.3 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 KOS21703.1 - 5.9e-13 49.2 0.0 2.1e-12 47.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain GAF_2 PF13185.1 KOS21703.1 - 2.8e-08 34.3 0.0 9.4e-08 32.6 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 KOS21703.1 - 1.8e-05 24.8 0.0 4.3e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 KOS21703.1 - 2.8e-05 23.3 0.0 7e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain HATPase_c_3 PF13589.1 KOS21703.1 - 0.0076 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NB-ARC PF00931.17 KOS21703.1 - 0.06 12.1 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain TPR_8 PF13181.1 KOS21703.1 - 0.17 11.7 0.9 3.1 7.7 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat NOA36 PF06524.7 KOS21703.1 - 0.31 10.2 8.7 0.75 8.9 6.1 1.5 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 KOS21703.1 - 0.87 7.4 7.1 1.5 6.6 4.9 1.2 1 0 0 1 1 1 0 Nop14-like family TPR_11 PF13414.1 KOS21703.1 - 1.1 8.8 6.4 0.53 9.9 0.2 3.2 3 1 0 3 3 3 0 TPR repeat Cwf_Cwc_15 PF04889.7 KOS21704.1 - 0.76 9.4 17.5 0.81 9.3 12.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Zip PF02535.17 KOS21704.1 - 0.95 8.4 17.5 1 8.2 12.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM176 PF14851.1 KOS21704.1 - 1 9.0 7.2 1.2 8.7 5.0 1.3 1 0 0 1 1 1 0 FAM176 family BTV_NS2 PF04514.7 KOS21704.1 - 1.1 8.0 7.1 1.2 7.9 4.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1510 PF07423.6 KOS21704.1 - 1.2 8.4 8.1 1.2 8.4 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 KOS21704.1 - 2.2 6.6 14.5 2.1 6.7 10.1 1.0 1 0 0 1 1 1 0 Daxx Family FYDLN_acid PF09538.5 KOS21704.1 - 2.7 8.6 22.1 3.2 8.3 15.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Sporozoite_P67 PF05642.6 KOS21704.1 - 2.9 5.6 7.9 2.8 5.6 5.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF688 PF05097.7 KOS21704.1 - 4.3 6.1 9.2 5.4 5.8 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) CDC45 PF02724.9 KOS21704.1 - 5 5.0 17.2 4.9 5.0 11.9 1.0 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 KOS21704.1 - 6.8 5.6 11.5 6.4 5.6 8.0 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.6 KOS21704.1 - 6.9 6.1 16.1 7.2 6.0 11.1 1.1 1 0 0 1 1 1 0 PPP4R2 Sigma70_ner PF04546.8 KOS21704.1 - 6.9 6.2 16.5 8.7 5.8 11.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 KOS21704.1 - 8.5 4.9 35.9 9.2 4.8 24.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 KOS21704.1 - 9.7 5.6 28.4 24 4.4 19.7 1.6 1 1 0 1 1 1 0 Nucleoplasmin Pyr_redox_3 PF13738.1 KOS21705.1 - 1.7e-19 70.7 0.0 2.2e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KOS21705.1 - 2.2e-12 45.9 0.0 2.6e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KOS21705.1 - 3.5e-10 39.3 0.0 4.9e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KOS21705.1 - 3.4e-08 33.6 0.0 7.1e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS21705.1 - 2.3e-06 27.5 0.7 2.1e-05 24.4 0.0 2.8 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KOS21705.1 - 0.0096 15.0 0.0 0.085 11.9 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KOS21705.1 - 0.059 13.7 0.2 13 6.2 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KOS21705.1 - 0.064 12.1 0.0 0.59 8.9 0.0 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.9 KOS21705.1 - 0.1 11.0 0.0 5 5.4 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein PLAC8 PF04749.12 KOS21709.1 - 1e-12 48.5 1.6 1.5e-12 48.0 1.1 1.2 1 0 0 1 1 1 1 PLAC8 family Glyco_transf_64 PF09258.5 KOS21710.1 - 9.1e-44 149.4 0.0 1.2e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain WD40 PF00400.27 KOS21713.1 - 1.4e-14 53.3 11.7 0.00013 21.6 0.3 7.3 8 0 0 8 8 8 4 WD domain, G-beta repeat Bromodomain PF00439.20 KOS21714.1 - 7.6e-10 38.5 0.0 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain GCN5L1 PF06320.8 KOS21715.1 - 2.3e-05 24.1 0.1 3.1e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) SOG2 PF10428.4 KOS21716.1 - 1.8e-86 290.6 5.3 2e-59 201.4 0.7 3.6 3 1 1 4 4 4 2 RAM signalling pathway protein LRR_4 PF12799.2 KOS21716.1 - 1.1e-16 60.0 10.3 4.8e-07 29.2 2.3 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS21716.1 - 1.4e-14 53.5 3.6 1.8e-07 30.7 0.7 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KOS21716.1 - 2.4e-09 35.9 6.1 0.031 14.2 0.2 5.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KOS21716.1 - 4e-07 29.1 5.0 2.7 8.5 0.1 5.0 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 KOS21716.1 - 0.0012 18.7 1.8 12 6.3 0.1 4.7 4 1 1 5 5 5 2 Leucine Rich repeat DEAD PF00270.24 KOS21717.1 - 5.4e-07 29.2 0.0 6.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS21718.1 - 1.7e-16 59.7 0.0 3.8e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2470 PF10615.4 KOS21719.1 - 7.9e-06 26.0 0.0 1.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Fungal_trans PF04082.13 KOS21720.1 - 6.1e-14 51.5 1.5 1.1e-13 50.7 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS21720.1 - 5.1e-06 26.2 8.2 1e-05 25.3 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_24 PF13578.1 KOS21721.1 - 1.1e-11 45.4 0.0 2.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KOS21721.1 - 3.5e-11 42.5 0.0 1.2e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KOS21721.1 - 0.00013 22.5 0.0 0.00022 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 KOS21721.1 - 0.036 13.3 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase Rgp1 PF08737.5 KOS21722.1 - 8.6e-108 361.0 0.0 2.9e-107 359.3 0.0 1.8 2 0 0 2 2 2 1 Rgp1 Arrestin_C PF02752.17 KOS21722.1 - 0.018 15.1 0.0 0.11 12.5 0.0 2.3 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain GlyL_C PF12524.3 KOS21722.1 - 0.026 14.4 1.3 0.13 12.1 0.0 2.8 2 0 0 2 2 2 0 dsDNA virus glycoprotein L C terminal Arrestin_N PF00339.24 KOS21722.1 - 0.041 13.7 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain PRP38_assoc PF12871.2 KOS21724.1 - 4.1 7.9 43.3 3.8 8.1 2.1 3.4 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term TPP_enzyme_N PF02776.13 KOS21725.1 - 7e-39 133.0 0.0 3.6e-38 130.7 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KOS21725.1 - 2.6e-22 79.0 0.1 1.1e-21 76.9 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KOS21725.1 - 3.2e-16 59.3 0.0 1.3e-15 57.4 0.0 2.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain PTP_N PF12453.3 KOS21725.1 - 0.14 11.7 4.3 0.31 10.6 3.0 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal Catalase PF00199.14 KOS21726.1 - 1.1e-161 537.8 0.4 1.5e-161 537.3 0.3 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KOS21726.1 - 4.2e-16 58.5 0.0 1.1e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 KOS21726.1 - 2.5e-12 46.4 0.0 6e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KOS21726.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative amidotransferase MAT1 PF06391.8 KOS21727.1 - 1 8.9 7.1 1.4 8.4 4.9 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Aldedh PF00171.17 KOS21728.1 - 8.8e-140 466.0 0.0 1.1e-139 465.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FR47 PF08445.5 KOS21729.1 - 4.5e-05 23.1 0.0 7.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KOS21729.1 - 0.001 19.1 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS21729.1 - 0.0037 17.2 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Peptidase_S28 PF05577.7 KOS21730.1 - 5.5e-43 147.1 0.0 1e-32 113.3 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Glyco_hydro_18 PF00704.23 KOS21731.1 - 5.3e-18 65.5 6.3 1.7e-17 63.9 4.3 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CSD PF00313.17 KOS21733.1 - 2e-28 97.9 1.2 2.1e-28 97.8 0.8 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain CusF_Ec PF11604.3 KOS21733.1 - 0.0025 17.6 0.1 0.0033 17.2 0.1 1.2 1 0 0 1 1 1 1 Copper binding periplasmic protein CusF OB_RNB PF08206.6 KOS21733.1 - 0.0035 16.8 0.1 0.0058 16.1 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain Serum_albumin PF00273.15 KOS21734.1 - 0.22 10.9 3.3 0.24 10.7 2.3 1.1 1 0 0 1 1 1 0 Serum albumin family Glyco_hyd_65N_2 PF14498.1 KOS21735.1 - 9.6e-46 156.3 0.1 1.4e-45 155.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DUF4640 PF15480.1 KOS21735.1 - 0.32 10.5 0.0 0.83 9.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4640) APG17 PF04108.7 KOS21737.1 - 4.7e-88 295.7 4.0 7.5e-87 291.8 2.8 1.9 1 1 0 1 1 1 1 Autophagy protein Apg17 RNA_pol_Rpb8 PF03870.10 KOS21737.1 - 0.039 14.1 0.1 0.91 9.7 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb8 Bacillus_HBL PF05791.6 KOS21737.1 - 0.054 12.8 0.1 0.14 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Cyt-b5 PF00173.23 KOS21738.1 - 4.6e-13 48.7 0.0 5.6e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TFR_dimer PF04253.10 KOS21739.1 - 5.3e-24 84.1 0.4 1e-23 83.2 0.0 1.7 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KOS21739.1 - 7.5e-16 58.3 0.0 4.1e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 KOS21739.1 - 3.7e-05 23.3 0.0 7.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 PA domain Vps35 PF03635.12 KOS21740.1 - 1.9e-291 968.7 0.4 2.2e-291 968.5 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Tim44 PF04280.10 KOS21741.1 - 4.9e-33 114.1 0.1 5.8e-32 110.6 0.0 2.3 2 0 0 2 2 2 1 Tim44-like domain Ribosomal_S11 PF00411.14 KOS21742.1 - 2.3e-07 30.9 0.0 3.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Peptidase_C97 PF05903.9 KOS21743.1 - 9.3e-33 113.1 0.0 1.2e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KOS21743.1 - 0.0016 18.3 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase YchF-GTPase_C PF06071.8 KOS21744.1 - 1.4e-32 111.3 0.4 3.5e-32 110.0 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KOS21744.1 - 6e-12 45.5 0.0 1.2e-11 44.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS21744.1 - 0.0012 18.1 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 KOS21744.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 TGS domain AAA_18 PF13238.1 KOS21744.1 - 0.083 13.2 0.8 36 4.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain BetaGal_dom3 PF13363.1 KOS21744.1 - 0.089 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 SecA_PP_bind PF01043.15 KOS21744.1 - 0.13 12.6 0.5 0.35 11.2 0.0 1.9 2 1 0 2 2 2 0 SecA preprotein cross-linking domain MobB PF03205.9 KOS21744.1 - 0.16 11.6 2.1 15 5.2 0.1 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AKAP95 PF04988.7 KOS21744.1 - 0.18 11.5 0.3 0.31 10.8 0.2 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) AAA_23 PF13476.1 KOS21744.1 - 0.27 11.5 7.9 1.8 8.8 5.5 2.1 1 1 0 1 1 1 0 AAA domain VPS9 PF02204.13 KOS21746.1 - 4.1e-20 71.7 0.0 1.1e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 KOS21746.1 - 2e-19 69.1 0.1 1.3e-11 44.3 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KOS21746.1 - 1e-13 51.4 0.0 1.3e-05 25.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KOS21746.1 - 9.8e-12 45.0 1.1 0.00042 20.7 0.0 5.2 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS21746.1 - 1.8e-09 36.9 0.2 0.11 12.7 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.25 KOS21746.1 - 1.8e-08 33.7 1.9 0.035 13.9 0.0 5.2 6 0 0 6 6 6 3 Ankyrin repeat PX PF00787.19 KOS21746.1 - 6e-05 22.7 0.0 0.00019 21.1 0.0 1.9 1 0 0 1 1 1 1 PX domain DUF2263 PF10021.4 KOS21747.1 - 1.3e-27 96.6 0.0 3.1e-27 95.4 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) PAP2 PF01569.16 KOS21748.1 - 5.6e-22 77.7 0.7 1.2e-21 76.7 0.5 1.5 1 0 0 1 1 1 1 PAP2 superfamily HIG_1_N PF04588.8 KOS21748.1 - 0.19 11.4 1.0 0.46 10.2 0.0 2.2 2 0 0 2 2 2 0 Hypoxia induced protein conserved region WW PF00397.21 KOS21749.1 - 2.6e-09 36.7 2.1 6.6e-09 35.4 1.5 1.7 1 0 0 1 1 1 1 WW domain FF PF01846.14 KOS21749.1 - 6.1e-08 32.4 5.3 1.4e-06 28.1 0.1 3.0 3 0 0 3 3 3 2 FF domain SPOC PF07744.8 KOS21750.1 - 1.1e-18 67.8 0.0 2.2e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.9 KOS21750.1 - 2.1e-14 53.5 0.3 2.1e-14 53.5 0.2 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 KOS21750.1 - 9.1e-08 31.6 9.4 1.6e-07 30.8 6.5 1.4 1 0 0 1 1 1 1 PHD-finger ECIST_Cterm PF14784.1 KOS21750.1 - 0.12 12.3 0.2 0.3 11.0 0.2 1.6 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein PHD_2 PF13831.1 KOS21750.1 - 2.3 7.6 6.9 4.4 6.7 4.8 1.4 1 0 0 1 1 1 0 PHD-finger Proteasome PF00227.21 KOS21751.1 - 2e-60 203.3 0.1 2.4e-60 203.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KOS21751.1 - 1e-14 53.5 0.2 6.9e-14 50.8 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 KOS21751.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit AMP-binding PF00501.23 KOS21753.1 - 2.8e-50 170.9 0.0 3.3e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme IF-2B PF01008.12 KOS21754.1 - 3.3e-14 52.5 0.0 4.3e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 KOS21754.1 - 1.4e-11 44.1 0.0 2.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain K_oxygenase PF13434.1 KOS21755.1 - 6e-84 281.8 0.0 1.1e-83 281.0 0.0 1.4 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KOS21755.1 - 3.3e-09 37.0 0.0 6.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS21755.1 - 0.00018 21.2 0.0 0.0014 18.4 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KOS21755.1 - 0.0039 17.1 0.0 0.05 13.4 0.0 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.23 KOS21756.1 - 9.2e-53 179.1 0.0 1.1e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KOS21757.1 - 1e-11 44.2 0.0 1.4e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Ribosomal_60s PF00428.14 KOS21757.1 - 0.027 14.8 0.5 0.091 13.1 0.3 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein RIO1 PF01163.17 KOS21758.1 - 8.1e-68 227.4 0.0 2.7e-67 225.7 0.0 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KOS21758.1 - 0.00055 19.7 0.1 0.82 9.3 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KOS21758.1 - 0.0034 16.4 0.1 0.45 9.5 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Glypican PF01153.14 KOS21758.1 - 1.2 7.7 9.3 0.053 12.1 2.5 1.5 2 0 0 2 2 2 0 Glypican Ceramidase PF05875.7 KOS21759.1 - 5.5e-72 242.0 6.4 6.6e-72 241.8 4.5 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.6 KOS21759.1 - 0.02 14.4 1.6 0.063 12.9 1.1 1.8 1 0 0 1 1 1 0 Trp-operon Leader Peptide DoxX_2 PF13564.1 KOS21759.1 - 0.98 9.4 12.8 0.81 9.6 1.9 3.2 2 1 1 3 3 3 0 DoxX-like family EamA PF00892.15 KOS21759.1 - 4.5 7.3 12.4 0.068 13.2 1.7 2.8 3 1 0 3 3 3 0 EamA-like transporter family Abhydrolase_6 PF12697.2 KOS21761.1 - 4.8e-14 52.7 0.2 7.8e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS21761.1 - 7.9e-11 41.9 0.0 1.3e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KOS21761.1 - 0.002 17.9 0.1 0.0041 16.9 0.1 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Bestrophin PF01062.16 KOS21762.1 - 5.4e-48 163.4 1.4 1.5e-46 158.6 0.9 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Arginosuc_synth PF00764.14 KOS21763.1 - 1.8e-112 376.2 0.0 1.4e-59 202.0 0.0 2.3 1 1 1 2 2 2 2 Arginosuccinate synthase Asn_synthase PF00733.16 KOS21763.1 - 0.00097 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 KOS21763.1 - 0.0025 17.1 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 KOS21763.1 - 0.083 11.4 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Mur_ligase PF01225.20 KOS21763.1 - 0.11 12.5 0.0 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Mur ligase family, catalytic domain MFS_1 PF07690.11 KOS21764.1 - 3.1e-30 105.1 38.8 4.5e-30 104.5 26.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS21764.1 - 1e-08 34.2 12.9 1e-08 34.2 9.0 2.2 2 2 1 3 3 3 1 Sugar (and other) transporter PRMT5 PF05185.11 KOS21765.1 - 1.1e-166 555.2 0.0 1.3e-166 554.9 0.0 1.0 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase DUF1772 PF08592.6 KOS21765.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Met_10 PF02475.11 KOS21765.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein OB_NTP_bind PF07717.11 KOS21766.1 - 3.4e-25 88.1 0.0 1.1e-24 86.4 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KOS21766.1 - 7e-23 80.5 0.0 1.9e-22 79.1 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KOS21766.1 - 2.1e-11 43.5 0.0 4.5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS21766.1 - 4.2e-07 29.6 0.3 1.7e-06 27.6 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KOS21766.1 - 2.4e-06 27.7 0.0 7.4e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 KOS21766.1 - 0.00075 18.9 0.2 0.0023 17.3 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 KOS21766.1 - 0.0059 15.5 0.0 0.015 14.1 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 KOS21766.1 - 0.0066 16.2 0.1 1.4 8.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_33 PF13671.1 KOS21766.1 - 0.037 13.8 0.1 0.22 11.3 0.1 2.4 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 KOS21766.1 - 0.047 13.4 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain Response_reg PF00072.19 KOS21766.1 - 0.05 13.6 0.6 0.42 10.6 0.1 2.6 3 0 0 3 3 3 0 Response regulator receiver domain CRM1_C PF08767.6 KOS21767.1 - 5e-130 433.0 1.6 5e-130 433.0 1.1 2.9 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 KOS21767.1 - 6.5e-42 142.9 14.1 2.6e-41 141.0 5.4 4.0 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 KOS21767.1 - 9.8e-09 35.0 0.1 4.7e-08 32.8 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.3 KOS21767.1 - 0.024 14.5 4.7 0.17 11.7 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) C8 PF08742.6 KOS21767.1 - 0.077 13.2 1.5 1.2 9.4 0.0 3.0 3 0 0 3 3 3 0 C8 domain Vac14_Fab1_bd PF12755.2 KOS21767.1 - 0.25 11.7 5.9 6 7.3 0.0 5.2 7 0 0 7 7 7 0 Vacuolar 14 Fab1-binding region Aminotran_5 PF00266.14 KOS21768.1 - 3.7e-27 95.0 0.0 4.6e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 KOS21768.1 - 0.007 16.2 0.5 0.021 14.6 0.0 2.0 2 1 0 2 2 2 1 B12 binding domain DDE_Tnp_1_4 PF13701.1 KOS21768.1 - 0.071 11.2 0.0 0.1 10.7 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 DEAD PF00270.24 KOS21769.1 - 2.1e-33 115.2 0.0 4.5e-33 114.1 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KOS21769.1 - 3.8e-19 67.9 0.0 6.8e-19 67.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KOS21769.1 - 2.2e-17 62.6 0.0 4.7e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KOS21769.1 - 0.00062 19.4 0.1 0.0048 16.6 0.1 2.3 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 KOS21769.1 - 0.014 15.2 1.5 0.031 14.1 0.0 2.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit KxDL PF10241.4 KOS21771.1 - 9e-32 108.8 2.0 1.2e-31 108.3 1.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein XylR_N PF06505.6 KOS21771.1 - 0.025 13.9 0.3 0.035 13.5 0.2 1.2 1 0 0 1 1 1 0 Activator of aromatic catabolism Sipho_Gp157 PF05565.6 KOS21771.1 - 0.1 12.1 0.4 0.15 11.6 0.3 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 DUF883 PF05957.8 KOS21771.1 - 1.3 9.4 6.4 14 6.2 4.2 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Mating_C PF12737.2 KOS21771.1 - 4.5 6.0 12.0 0.37 9.6 3.2 2.3 2 1 0 2 2 2 0 C-terminal domain of homeodomain 1 CTP_transf_1 PF01148.15 KOS21772.1 - 5.8e-16 58.9 12.4 3.4e-13 49.8 5.4 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family ATG27 PF09451.5 KOS21774.1 - 0.11 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 FAM75 PF14650.1 KOS21774.1 - 0.14 11.5 11.8 0.18 11.1 8.1 1.1 1 0 0 1 1 1 0 FAM75 family PAT1 PF09770.4 KOS21774.1 - 4.2 5.4 14.0 5.8 5.0 9.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RIC3 PF15361.1 KOS21774.1 - 5.8 7.1 8.2 8.4 6.6 5.7 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 IBR PF01485.16 KOS21775.1 - 3.6e-08 33.1 21.7 3.5e-05 23.5 8.8 4.2 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 KOS21775.1 - 1.2e-05 25.0 6.1 1.2e-05 25.0 4.2 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KOS21775.1 - 0.0056 16.6 6.3 0.0056 16.6 4.3 4.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS21775.1 - 0.0071 16.0 4.8 0.0071 16.0 3.3 3.6 3 0 0 3 3 3 1 zinc-RING finger domain ADH_N PF08240.7 KOS21776.1 - 0.00036 20.2 0.0 0.00051 19.7 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF4336 PF14234.1 KOS21777.1 - 3.5e-12 46.1 0.1 8.4e-08 31.7 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) MMR_HSR1 PF01926.18 KOS21779.1 - 4.2e-11 42.8 0.1 7.7e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS21779.1 - 0.0012 18.1 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.1 KOS21779.1 - 0.0032 17.7 0.1 0.0051 17.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS21779.1 - 0.0035 18.1 0.2 0.0073 17.1 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KOS21779.1 - 0.005 16.3 0.1 0.0079 15.7 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KOS21779.1 - 0.0073 15.5 0.1 0.0087 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 KOS21779.1 - 0.021 14.0 0.1 0.048 12.8 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.13 KOS21779.1 - 0.029 13.8 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.1 KOS21779.1 - 0.04 13.8 0.2 0.062 13.2 0.2 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KOS21779.1 - 0.041 14.3 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_15 PF13175.1 KOS21779.1 - 0.063 12.3 0.0 0.063 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.13 KOS21779.1 - 0.064 12.2 0.0 0.087 11.8 0.0 1.1 1 0 0 1 1 1 0 Septin MobB PF03205.9 KOS21779.1 - 0.065 12.9 0.1 0.095 12.4 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KOS21779.1 - 0.066 13.2 0.1 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ArgK PF03308.11 KOS21779.1 - 0.066 11.9 0.3 0.17 10.6 0.0 1.6 1 1 1 2 2 2 0 ArgK protein MCM PF00493.18 KOS21779.1 - 0.078 11.7 0.1 0.099 11.4 0.1 1.1 1 0 0 1 1 1 0 MCM2/3/5 family IIGP PF05049.8 KOS21779.1 - 0.089 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 KOS21779.1 - 0.12 12.1 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Dynamin family ABC_tran PF00005.22 KOS21779.1 - 0.13 12.6 0.1 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 KOS21779.1 - 0.14 12.0 0.1 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Peptidase_M24 PF00557.19 KOS21780.1 - 1.2e-57 194.9 0.2 1.5e-57 194.5 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KOS21780.1 - 7.9e-21 73.8 0.0 2.8e-20 72.0 0.0 1.9 2 1 0 2 2 2 1 Aminopeptidase P, N-terminal domain DUF814 PF05670.8 KOS21781.1 - 1.5e-16 60.0 0.5 5.2e-15 55.1 0.3 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF814) HeLo PF14479.1 KOS21783.1 - 2.4e-07 30.7 0.4 0.0025 17.6 0.0 2.3 1 1 1 2 2 2 2 Prion-inhibition and propagation Cnl2_NKP2 PF09447.5 KOS21783.1 - 0.031 13.9 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 Cnl2/NKP2 family protein NUDE_C PF04880.8 KOS21784.1 - 2.9e-20 73.2 2.6 2.9e-20 73.2 1.8 2.5 2 0 0 2 2 2 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 KOS21784.1 - 0.0014 18.9 9.4 0.0014 18.9 6.5 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF904) zf-C4H2 PF10146.4 KOS21784.1 - 0.0068 16.4 4.4 0.0068 16.4 3.1 2.5 1 1 1 2 2 1 1 Zinc finger-containing protein WEMBL PF05701.6 KOS21784.1 - 0.03 12.8 34.3 0.076 11.4 23.8 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF972 PF06156.8 KOS21784.1 - 0.24 11.7 22.2 0.22 11.8 6.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Amino_oxidase PF01593.19 KOS21784.1 - 0.24 10.4 5.0 0.43 9.6 3.5 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Chibby PF14645.1 KOS21784.1 - 0.4 10.5 14.3 0.093 12.6 3.0 2.5 1 1 1 2 2 2 0 Chibby family tRNA-synt_1d PF00750.14 KOS21784.1 - 0.91 8.2 6.7 0.96 8.1 4.1 1.3 1 1 0 1 1 1 0 tRNA synthetases class I (R) CENP-F_leu_zip PF10473.4 KOS21784.1 - 1.9 8.3 38.6 2.8 7.7 7.3 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GrpE PF01025.14 KOS21784.1 - 5.1 6.6 29.4 0.56 9.7 3.3 3.2 1 1 2 3 3 3 0 GrpE IncA PF04156.9 KOS21784.1 - 5.4 6.5 37.7 1.6 8.2 13.3 2.8 2 1 1 3 3 3 0 IncA protein DUF3584 PF12128.3 KOS21784.1 - 5.8 4.0 26.5 7.9 3.6 18.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.16 KOS21784.1 - 6 6.2 34.6 3 7.2 7.4 2.4 2 1 1 3 3 3 0 Intermediate filament protein Seryl_tRNA_N PF02403.17 KOS21784.1 - 6.7 6.7 24.2 3.8 7.5 5.4 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ACC_central PF08326.7 KOS21785.1 - 2.5e-255 849.0 0.0 3.1e-255 848.7 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KOS21785.1 - 6.1e-177 588.8 0.0 8.9e-177 588.3 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KOS21785.1 - 2e-52 177.5 0.0 4.7e-52 176.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KOS21785.1 - 7.6e-24 83.9 0.1 1.6e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KOS21785.1 - 2.5e-21 75.6 0.0 1.5e-18 66.7 0.0 3.6 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KOS21785.1 - 8.1e-17 60.6 0.2 2.2e-16 59.2 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KOS21785.1 - 1.3e-10 41.3 0.0 3.6e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KOS21785.1 - 0.00085 18.7 0.0 0.0029 17.0 0.0 2.0 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 KOS21785.1 - 0.0017 18.0 0.0 0.0055 16.3 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_3 PF02655.9 KOS21785.1 - 0.0048 16.7 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 KOS21785.1 - 0.024 14.0 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain IpaB_EvcA PF03278.8 KOS21785.1 - 0.1 11.8 0.4 0.25 10.5 0.3 1.6 1 0 0 1 1 1 0 IpaB/EvcA family BolA PF01722.13 KOS21786.1 - 3.4e-15 55.7 0.0 3.8e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Flavokinase PF01687.12 KOS21787.1 - 2.7e-10 40.1 0.0 4.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase NST1 PF13945.1 KOS21790.1 - 9.1e-50 169.3 14.7 9.1e-50 169.3 10.2 5.3 3 2 1 4 4 4 1 Salt tolerance down-regulator HET PF06985.6 KOS21793.1 - 0.0014 18.7 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cutinase PF01083.17 KOS21794.1 - 1.6e-42 145.2 0.9 2.2e-42 144.7 0.6 1.1 1 0 0 1 1 1 1 Cutinase MSA-2c PF12238.3 KOS21794.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c MFS_1 PF07690.11 KOS21795.1 - 2.5e-22 79.0 35.7 1e-21 77.0 24.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KOS21795.1 - 1.8e-06 26.4 12.4 2.4e-06 26.0 8.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4231 PF14015.1 KOS21795.1 - 8.8 6.3 8.4 41 4.2 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Shisa PF13908.1 KOS21796.1 - 0.015 15.5 3.0 0.016 15.3 0.5 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Inhibitor_I78 PF11720.3 KOS21797.1 - 1.6e-09 37.3 0.0 2.5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 KOS21797.1 - 0.00018 21.5 0.0 0.00026 21.0 0.0 1.2 1 0 0 1 1 1 1 Potato inhibitor I family PUA PF01472.15 KOS21798.1 - 5.8e-12 45.1 0.1 7.1e-06 25.6 0.0 2.1 2 0 0 2 2 2 2 PUA domain Tcf25 PF04910.9 KOS21800.1 - 2.9e-66 223.8 0.0 4.9e-66 223.1 0.0 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Shadoo PF14999.1 KOS21800.1 - 0.017 14.9 5.4 0.058 13.2 3.8 1.9 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective NST1 PF13945.1 KOS21800.1 - 2.3 8.2 8.8 6.5 6.7 6.1 1.7 1 0 0 1 1 1 0 Salt tolerance down-regulator BUD22 PF09073.5 KOS21800.1 - 3.9 6.4 24.1 7.1 5.5 16.7 1.3 1 0 0 1 1 1 0 BUD22 Menin PF05053.8 KOS21800.1 - 5.7 4.9 7.4 9.3 4.2 5.1 1.4 1 0 0 1 1 1 0 Menin LSM14 PF12701.2 KOS21801.1 - 8.2e-26 89.6 0.0 9.7e-26 89.4 0.0 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.1 KOS21801.1 - 0.00071 19.4 0.0 0.00095 19.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain V-SNARE PF05008.10 KOS21802.1 - 7.1e-21 74.1 2.2 7.1e-21 74.1 1.5 1.6 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 KOS21802.1 - 4.3e-16 58.7 1.8 4.3e-16 58.7 1.3 2.7 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KOS21802.1 - 0.0006 19.4 0.3 0.0018 17.9 0.2 1.8 1 0 0 1 1 1 1 Sec20 DUF1513 PF07433.6 KOS21802.1 - 0.036 12.9 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) Fusion_gly PF00523.13 KOS21802.1 - 0.041 11.9 1.5 0.29 9.1 0.3 2.0 2 0 0 2 2 2 0 Fusion glycoprotein F0 Baculo_E56 PF04639.7 KOS21802.1 - 0.049 12.2 0.1 0.08 11.5 0.1 1.3 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope RRF PF01765.14 KOS21802.1 - 0.096 12.1 0.3 0.15 11.5 0.2 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Use1 PF09753.4 KOS21802.1 - 0.47 9.8 3.4 3.7 6.9 2.3 2.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 Amino_oxidase PF01593.19 KOS21803.1 - 3.7e-14 52.6 0.2 0.00045 19.4 0.0 3.1 3 0 0 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KOS21803.1 - 1e-11 44.6 0.1 2.9e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KOS21803.1 - 0.00011 22.3 0.0 0.011 15.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KOS21803.1 - 0.00012 21.0 0.1 0.00022 20.2 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KOS21803.1 - 0.0005 19.8 0.1 0.3 10.8 0.0 2.6 2 1 1 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.9 KOS21803.1 - 0.0038 15.7 0.0 0.74 8.2 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 KOS21803.1 - 0.0082 16.0 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS21803.1 - 0.023 15.1 0.0 0.12 12.8 0.0 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CtaG_Cox11 PF04442.9 KOS21804.1 - 1e-56 190.9 0.0 1.4e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 zf-Sec23_Sec24 PF04810.10 KOS21804.1 - 0.035 13.6 0.1 0.076 12.5 0.1 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger SR-25 PF10500.4 KOS21804.1 - 1.2 8.5 7.3 1.9 7.9 5.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_C58 PF03543.9 KOS21805.1 - 0.064 12.7 0.0 0.064 12.7 0.0 1.9 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen SPT6_acidic PF14632.1 KOS21805.1 - 4 7.6 27.0 2.5 8.3 3.9 3.5 3 1 0 3 3 3 0 Acidic N-terminal SPT6 Prefoldin_2 PF01920.15 KOS21806.1 - 4.4e-23 81.0 2.2 5.6e-23 80.7 1.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tektin PF03148.9 KOS21806.1 - 0.026 13.1 5.2 0.39 9.1 0.0 2.0 2 0 0 2 2 2 0 Tektin family FTA4 PF13093.1 KOS21806.1 - 0.056 12.8 1.5 0.063 12.6 1.1 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Osmo_CC PF08946.5 KOS21806.1 - 0.058 13.4 0.0 0.058 13.4 0.0 2.0 3 0 0 3 3 3 0 Osmosensory transporter coiled coil eIF-4B PF06273.6 KOS21806.1 - 0.24 10.0 2.4 0.29 9.8 1.7 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B GrpE PF01025.14 KOS21807.1 - 0.0015 18.0 5.2 0.0015 18.0 3.6 2.0 2 0 0 2 2 2 1 GrpE Metal_hydrol PF10118.4 KOS21807.1 - 0.0035 16.8 2.1 0.0056 16.1 1.5 1.2 1 0 0 1 1 1 1 Predicted metal-dependent hydrolase FlxA PF14282.1 KOS21807.1 - 0.039 13.9 18.7 0.6 10.0 8.9 3.5 2 1 0 2 2 2 0 FlxA-like protein GRP PF07172.6 KOS21807.1 - 0.14 12.6 11.5 0.46 10.9 8.0 1.8 1 0 0 1 1 1 0 Glycine rich protein family IncA PF04156.9 KOS21807.1 - 0.36 10.4 7.7 0.57 9.7 5.3 1.3 1 0 0 1 1 1 0 IncA protein HSP70 PF00012.15 KOS21808.1 - 1.5e-58 198.1 16.1 6.8e-57 192.7 0.1 2.9 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 KOS21808.1 - 0.00048 18.8 0.1 0.0011 17.6 0.1 1.7 1 0 0 1 1 1 1 MreB/Mbl protein Profilin PF00235.14 KOS21809.1 - 1.4e-17 63.9 0.0 1.8e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Profilin GAT PF03127.9 KOS21810.1 - 3.9e-15 55.6 0.1 7.6e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 KOS21810.1 - 0.0047 16.5 0.0 0.0087 15.6 0.0 1.4 1 0 0 1 1 1 1 VHS domain ADH_N PF08240.7 KOS21811.1 - 5.2e-28 96.9 0.1 9.9e-28 96.0 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KOS21811.1 - 1.6e-17 63.2 0.7 3.4e-17 62.2 0.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_2 PF00890.19 KOS21811.1 - 0.0063 15.4 2.6 0.0095 14.8 1.8 1.2 1 0 0 1 1 1 1 FAD binding domain UDPG_MGDP_dh_N PF03721.9 KOS21811.1 - 0.06 12.7 0.1 0.13 11.5 0.1 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KOS21811.1 - 0.11 12.1 0.5 0.2 11.2 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KOS21811.1 - 0.14 11.6 0.3 0.23 10.8 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 KOS21812.1 - 2.6e-28 99.0 0.2 3.8e-28 98.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS21812.1 - 6.6e-21 75.1 0.0 8.4e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS21812.1 - 9.4e-13 48.2 0.3 2.2e-12 47.0 0.2 1.7 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KOS21812.1 - 0.0011 18.7 0.3 0.0025 17.5 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KOS21812.1 - 0.0086 16.0 1.6 0.11 12.5 0.6 2.7 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KOS21812.1 - 0.027 13.9 0.3 0.2 11.0 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.11 KOS21812.1 - 0.054 12.9 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 KOS21812.1 - 0.056 12.5 0.3 0.11 11.5 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KOS21812.1 - 0.082 13.3 0.5 0.77 10.2 0.1 2.4 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SNARE PF05739.14 KOS21813.1 - 1.2e-17 63.2 2.3 5.1e-17 61.3 0.2 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KOS21813.1 - 2.8e-15 56.3 1.9 7.6e-15 54.9 0.1 2.5 2 1 0 2 2 2 1 Syntaxin Sporozoite_P67 PF05642.6 KOS21813.1 - 0.0011 16.9 5.2 0.0013 16.7 3.6 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Sed5p PF11416.3 KOS21813.1 - 0.0075 15.6 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 Integral membrane protein Sed5p MCPsignal PF00015.16 KOS21813.1 - 0.014 14.9 0.3 0.014 14.9 0.2 2.2 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.7 KOS21813.1 - 0.089 13.0 3.0 16 5.8 0.1 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 KOS21813.1 - 0.25 9.9 3.3 0.25 9.9 0.8 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Aldo_ket_red PF00248.16 KOS21814.1 - 3.7e-34 117.8 0.0 2.3e-16 59.4 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family NmrA PF05368.8 KOS21814.1 - 0.0095 15.2 0.0 0.26 10.5 0.0 2.0 1 1 1 2 2 2 2 NmrA-like family Abhydrolase_6 PF12697.2 KOS21815.1 - 9e-26 91.1 5.8 1.3e-25 90.5 4.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS21815.1 - 1.1e-11 44.7 0.0 1.2e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS21815.1 - 1.1e-11 44.6 0.1 1.8e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KOS21815.1 - 0.004 16.9 0.1 0.013 15.2 0.0 1.9 1 1 1 2 2 2 1 Putative lysophospholipase Sec2p PF06428.6 KOS21816.1 - 9.7e-23 79.9 13.3 9.7e-23 79.9 9.3 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p RBD-FIP PF09457.5 KOS21816.1 - 0.41 10.4 6.9 4.8 7.0 2.2 2.6 2 0 0 2 2 2 0 FIP domain DUF4600 PF15372.1 KOS21816.1 - 6.3 7.0 19.1 7.6 6.7 5.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) PRP21_like_P PF12230.3 KOS21817.1 - 5.3e-55 186.4 10.7 1.3e-54 185.1 7.4 1.6 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KOS21817.1 - 1.6e-39 133.3 1.1 7e-20 70.4 0.0 2.3 2 0 0 2 2 2 2 Surp module PMT PF02366.13 KOS21818.1 - 9.4e-75 251.1 17.1 9.4e-75 251.1 11.8 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KOS21818.1 - 5.9e-53 179.2 0.0 1.6e-52 177.8 0.0 1.8 1 0 0 1 1 1 1 MIR domain Plasmodium_HRP PF05403.6 KOS21818.1 - 0.014 14.9 6.1 0.023 14.2 4.2 1.2 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) DUF221 PF02714.10 KOS21820.1 - 4.9e-90 301.6 19.0 8.3e-90 300.9 13.2 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KOS21820.1 - 2.1e-34 118.3 1.1 2.1e-34 118.3 0.7 2.2 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KOS21820.1 - 1.3e-16 60.8 0.5 4.6e-16 59.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) Adeno_E3_CR2 PF02439.10 KOS21820.1 - 0.6 9.6 3.9 2.4 7.7 0.3 2.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 adh_short PF00106.20 KOS21821.1 - 4.1e-32 111.4 4.3 5.6e-32 110.9 3.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS21821.1 - 2.5e-23 83.1 0.5 8.9e-23 81.2 0.4 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS21821.1 - 3.7e-16 59.3 2.1 5.1e-16 58.8 1.4 1.1 1 0 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.9 KOS21821.1 - 0.0037 16.6 0.2 0.007 15.7 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KOS21821.1 - 0.0038 16.9 0.8 0.0061 16.2 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 KOS21821.1 - 0.088 12.6 2.0 0.13 12.0 1.1 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TPK_catalytic PF04263.11 KOS21822.1 - 0.081 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain Glycos_transf_2 PF00535.21 KOS21824.1 - 1.5e-33 115.8 0.0 1.8e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KOS21824.1 - 3.6e-14 53.1 0.0 7e-14 52.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KOS21824.1 - 9.5e-08 31.4 0.0 1.2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KOS21824.1 - 9e-07 28.3 0.0 1.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 KOS21824.1 - 0.024 14.9 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 KOS21824.1 - 0.09 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 TMA7 PF09072.5 KOS21825.1 - 1e-26 93.1 14.8 1.1e-26 93.0 10.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Nefa_Nip30_N PF10187.4 KOS21825.1 - 0.0047 17.0 1.1 0.0057 16.8 0.7 1.1 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Pkinase PF00069.20 KOS21826.1 - 8.1e-51 172.6 0.0 1e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS21826.1 - 1.5e-21 76.6 0.0 2.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KOS21826.1 - 0.0091 14.8 0.1 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 KOS21826.1 - 0.012 14.6 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 KOS21826.1 - 0.024 13.9 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KOS21826.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family NADPH_Ox PF08414.5 KOS21826.1 - 0.13 12.3 0.0 0.39 10.8 0.0 1.8 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase WD40 PF00400.27 KOS21827.1 - 4.3e-06 26.4 2.0 0.81 9.6 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF3295 PF11702.3 KOS21827.1 - 9.3 5.1 13.0 14 4.5 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) HlyIII PF03006.15 KOS21828.1 - 4.1e-59 199.6 15.1 4.9e-59 199.4 10.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF418 PF04235.7 KOS21828.1 - 0.33 10.6 8.4 0.16 11.6 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF418) DUF4095 PF13338.1 KOS21828.1 - 0.52 10.4 3.9 0.36 10.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4095) Yip1 PF04893.12 KOS21828.1 - 1.3 8.4 24.9 0.48 9.8 11.0 2.8 1 1 1 2 2 2 0 Yip1 domain DUF962 PF06127.6 KOS21828.1 - 1.8 8.4 5.1 1.1 9.1 1.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Syntaxin_2 PF14523.1 KOS21829.1 - 6.8e-24 83.8 4.0 6.8e-24 83.8 2.8 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KOS21829.1 - 1e-14 53.9 4.0 3.2e-14 52.3 2.8 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 KOS21829.1 - 0.004 17.2 2.1 0.004 17.2 1.4 2.2 2 1 0 2 2 2 1 Syntaxin DUF883 PF05957.8 KOS21829.1 - 0.021 15.2 7.1 0.37 11.2 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Synaptobrevin PF00957.16 KOS21829.1 - 0.44 10.1 2.5 1.4 8.5 1.7 2.0 1 1 0 1 1 1 0 Synaptobrevin DUF4635 PF15466.1 KOS21829.1 - 1.6 7.9 5.4 18 4.6 0.2 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4635) 60KD_IMP PF02096.15 KOS21830.1 - 1.3e-05 25.0 0.0 3.8e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 60Kd inner membrane protein PIG-H PF10181.4 KOS21831.1 - 1.6e-25 88.5 0.0 2.3e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DUF2189 PF09955.4 KOS21831.1 - 0.015 15.1 4.5 0.063 13.2 0.5 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) PseudoU_synth_1 PF01416.15 KOS21832.1 - 9.3e-28 96.7 0.0 5.9e-21 74.8 0.0 3.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase Snf7 PF03357.16 KOS21833.1 - 4e-22 78.3 4.1 4e-22 78.3 2.8 2.1 2 0 0 2 2 2 1 Snf7 SQS_PSY PF00494.14 KOS21833.1 - 0.0077 15.5 3.0 0.013 14.7 0.3 2.1 2 0 0 2 2 2 1 Squalene/phytoene synthase ABC_trans_N PF14510.1 KOS21833.1 - 0.19 11.8 1.0 1.2 9.2 0.1 2.4 2 1 0 2 2 2 0 ABC-transporter extracellular N-terminal GAS PF13851.1 KOS21833.1 - 1 8.4 9.6 0.038 13.1 2.3 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4611 PF15387.1 KOS21833.1 - 2.1 8.5 7.6 20 5.4 2.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TPR_MLP1_2 PF07926.7 KOS21833.1 - 2.4 7.8 8.6 0.4 10.4 1.9 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 KOS21833.1 - 2.7 6.8 8.1 1.7 7.5 4.5 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Guanylin PF02058.10 KOS21834.1 - 0.0063 16.5 0.7 0.012 15.7 0.5 1.5 1 0 0 1 1 1 1 Guanylin precursor DUF4582 PF15189.1 KOS21834.1 - 0.01 15.1 1.0 0.015 14.5 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4582) DIRP PF06584.8 KOS21834.1 - 0.015 15.1 0.7 0.024 14.5 0.5 1.3 1 0 0 1 1 1 0 DIRP Herpes_DNAp_acc PF04929.7 KOS21834.1 - 0.55 9.1 5.4 0.66 8.8 3.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor NICE-3 PF07406.6 KOS21835.1 - 0.00013 21.4 0.2 0.03 13.8 0.0 2.5 2 1 0 2 2 2 2 NICE-3 protein DUF4129 PF13559.1 KOS21835.1 - 0.00014 21.7 0.2 0.00035 20.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Ndc1_Nup PF09531.5 KOS21836.1 - 2e-116 389.8 1.8 2.4e-116 389.5 1.2 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Ras PF00071.17 KOS21837.1 - 1.6e-17 63.3 0.0 2.4e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS21837.1 - 2.1e-09 37.9 0.0 2.8e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS21837.1 - 0.00015 21.0 0.0 0.00051 19.3 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KOS21837.1 - 0.016 13.9 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PduV-EutP PF10662.4 KOS21837.1 - 0.15 11.5 0.1 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_pol_Rpb4 PF03874.11 KOS21838.1 - 1.3e-24 86.4 0.0 1.5e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 HTH_32 PF13565.1 KOS21838.1 - 0.00056 20.6 0.1 0.0011 19.7 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Polysacc_deac_2 PF04748.8 KOS21838.1 - 0.023 13.7 0.0 0.037 13.0 0.0 1.5 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase GatB_Yqey PF02637.13 KOS21838.1 - 0.086 12.5 0.0 0.15 11.8 0.0 1.4 1 1 0 1 1 1 0 GatB domain Peptidase_M1 PF01433.15 KOS21839.1 - 4.5e-132 440.8 0.2 8.1e-132 439.9 0.1 1.4 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 KOS21839.1 - 1e-63 215.5 0.0 1.5e-63 215.0 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KOS21839.1 - 5.9e-22 78.0 3.9 7.8e-22 77.6 0.4 2.4 1 1 1 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 KOS21839.1 - 0.18 11.5 0.6 0.56 9.9 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF45 SDA1 PF05285.7 KOS21841.1 - 1.6e-91 306.9 38.1 1.6e-91 306.9 26.4 2.3 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 KOS21841.1 - 1.7e-20 73.0 0.5 4.2e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 NUC130/3NT domain Mating_N PF12731.2 KOS21841.1 - 0.01 15.6 0.2 0.05 13.4 0.0 2.1 2 0 0 2 2 2 0 Mating-type protein beta 1 Mito_carr PF00153.22 KOS21842.1 - 4.1e-47 157.8 8.8 2.5e-17 62.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein P21-Arc PF04062.9 KOS21845.1 - 2.9e-78 261.6 0.0 3.4e-78 261.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.8 KOS21846.1 - 2.9e-64 217.0 0.0 1.2e-63 215.0 0.0 1.8 1 1 0 1 1 1 1 Gcd10p family DUF3628 PF12300.3 KOS21846.1 - 0.028 14.4 6.3 0.32 11.0 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) DUF3138 PF11336.3 KOS21846.1 - 0.083 11.0 6.2 3.5 5.7 4.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF3292 PF11696.3 KOS21846.1 - 0.42 8.4 3.6 2.6 5.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) BAF1_ABF1 PF04684.8 KOS21846.1 - 1.5 7.5 5.3 2.3 6.9 3.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ribosomal_60s PF00428.14 KOS21846.1 - 2.9 8.3 15.9 9.8 6.6 11.0 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein FMO-like PF00743.14 KOS21847.1 - 4.9e-33 114.1 0.0 1.8e-24 85.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KOS21847.1 - 2.5e-10 40.7 0.0 6.2e-09 36.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KOS21847.1 - 8.1e-09 34.8 0.0 4.2e-07 29.2 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KOS21847.1 - 1.7e-07 31.3 0.0 6.1e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS21847.1 - 5.4e-07 29.5 0.1 0.047 13.4 0.0 3.3 2 1 1 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KOS21847.1 - 0.00044 20.2 0.0 0.0015 18.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KOS21847.1 - 0.0053 15.6 0.0 7.2 5.4 0.1 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.12 KOS21847.1 - 0.039 13.0 0.2 0.79 8.7 0.0 2.6 3 0 0 3 3 3 0 Thi4 family FAD_binding_3 PF01494.14 KOS21847.1 - 0.11 11.4 0.9 0.13 11.3 0.1 1.4 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.11 KOS21848.1 - 9.7e-21 73.8 25.7 9.7e-21 73.8 17.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS21848.1 - 5e-05 22.0 7.5 5e-05 22.0 5.2 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter DUF2811 PF10929.3 KOS21848.1 - 0.003 17.5 0.1 0.0078 16.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2811) DUF3938 PF13074.1 KOS21848.1 - 0.011 15.5 0.7 0.03 14.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) DUF1049 PF06305.6 KOS21848.1 - 0.11 12.0 0.1 0.11 12.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF373 PF04123.8 KOS21848.1 - 0.15 11.0 1.6 0.34 9.8 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF373) COX6A PF02046.10 KOS21849.1 - 2.2e-35 121.0 7.4 4.7e-35 119.9 5.1 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa Apc5 PF12862.2 KOS21850.1 - 3e-32 110.3 3.3 7.2e-32 109.1 2.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_14 PF13428.1 KOS21850.1 - 1.8e-06 28.0 14.5 2.1 9.2 0.0 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KOS21850.1 - 0.00045 20.4 8.2 1.8 8.9 0.3 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KOS21850.1 - 0.00064 19.3 2.9 15 5.6 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KOS21850.1 - 0.00072 19.4 10.7 0.28 11.1 0.0 5.4 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 KOS21850.1 - 0.0017 17.9 1.5 4.6 6.9 0.1 4.1 4 0 0 4 4 4 2 TPR repeat PPR_3 PF13812.1 KOS21850.1 - 0.01 16.0 2.6 1.7 9.1 0.0 5.6 7 0 0 7 7 7 1 Pentatricopeptide repeat domain TPR_2 PF07719.12 KOS21850.1 - 0.012 15.4 3.5 0.75 9.8 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 KOS21850.1 - 0.023 15.3 15.5 3.8 8.3 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.15 KOS21850.1 - 0.073 13.0 0.0 3.2 7.9 0.0 3.6 4 0 0 4 4 3 0 PPR repeat TPR_1 PF00515.23 KOS21850.1 - 0.13 11.9 4.3 14 5.4 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KOS21850.1 - 0.29 11.6 0.0 0.29 11.6 0.0 5.5 6 0 0 6 6 4 0 Tetratricopeptide repeat CIA30 PF08547.7 KOS21851.1 - 5.2e-39 133.6 0.0 7.9e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 KOS21851.1 - 0.0056 16.3 0.0 0.0082 15.8 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) WW PF00397.21 KOS21851.1 - 0.024 14.4 0.1 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 WW domain Tim44 PF04280.10 KOS21852.1 - 3e-05 24.0 0.0 5.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain RRM_1 PF00076.17 KOS21853.1 - 1.9e-07 30.5 0.0 4.4e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS21853.1 - 1.1e-05 25.2 0.0 2.6e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS21853.1 - 4.9e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SSF PF00474.12 KOS21854.1 - 1.9e-07 30.1 27.9 2.7e-06 26.2 19.4 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family EOS1 PF12326.3 KOS21855.1 - 6.8e-25 87.4 10.0 1.9e-21 76.3 2.0 2.3 1 1 1 2 2 2 2 N-glycosylation protein SUI1 PF01253.17 KOS21856.1 - 7.8e-28 96.1 4.5 1e-27 95.7 3.1 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Hexokinase_2 PF03727.11 KOS21856.1 - 0.02 14.1 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Hexokinase AdoMet_MTase PF07757.8 KOS21857.1 - 7.3e-35 119.4 0.0 3.2e-34 117.4 0.0 1.9 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Dioxygenase_C PF00775.16 KOS21858.1 - 1.4e-48 164.6 0.0 1.8e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KOS21858.1 - 9.6e-11 41.5 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KOS21858.1 - 1.2e-05 25.2 0.0 3.3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 KOS21858.1 - 0.012 15.3 0.1 0.027 14.2 0.1 1.6 1 0 0 1 1 1 0 Cna protein B-type domain His_Phos_1 PF00300.17 KOS21859.1 - 4.2e-30 104.9 0.0 5e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RskA PF10099.4 KOS21860.1 - 0.16 11.6 0.8 0.18 11.5 0.5 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA UCH PF00443.24 KOS21861.1 - 2e-53 181.2 0.0 2.5e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS21861.1 - 7e-21 74.9 2.8 2.4e-19 69.8 1.9 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KOS21861.1 - 3.8e-11 42.2 0.1 9.3e-11 40.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUF3573 PF12097.3 KOS21861.1 - 0.17 10.4 2.3 0.62 8.6 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) DUF3682 PF12446.3 KOS21861.1 - 0.67 10.2 13.9 1.8 8.8 9.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Zip PF02535.17 KOS21861.1 - 0.72 8.7 1.9 1.1 8.2 1.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ARPC4 PF05856.7 KOS21862.1 - 8.5e-75 249.8 3.5 9.5e-75 249.6 2.4 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RRM_6 PF14259.1 KOS21864.1 - 1.5e-05 24.9 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Lipoprotein_19 PF13617.1 KOS21864.1 - 0.12 12.0 0.1 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 YnbE-like lipoprotein CRAL_TRIO PF00650.15 KOS21865.1 - 2e-17 63.1 0.0 2.9e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KOS21865.1 - 0.00084 19.4 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PRA-PH PF01503.12 KOS21865.1 - 2.3 8.5 8.3 16 5.8 0.1 2.7 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase SET PF00856.23 KOS21866.1 - 8e-19 68.5 1.0 8e-19 68.5 0.7 3.1 2 1 0 2 2 2 1 SET domain Pol_alpha_B_N PF08418.5 KOS21867.1 - 3.5 7.1 9.1 3.9 6.9 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal zf-DHHC PF01529.15 KOS21868.1 - 5.2e-28 97.5 2.8 5.2e-28 97.5 1.9 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.1 KOS21868.1 - 0.00038 19.9 6.5 0.096 12.0 1.4 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) DUF412 PF04217.8 KOS21868.1 - 0.13 12.0 1.6 0.36 10.6 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF412 COX4_pro_2 PF07835.7 KOS21868.1 - 0.26 11.3 3.6 0.66 9.9 0.4 2.7 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF3353 PF11833.3 KOS21868.1 - 0.29 10.5 4.1 0.4 10.1 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) AA_permease_2 PF13520.1 KOS21868.1 - 0.3 9.5 12.6 0.033 12.7 0.9 2.0 2 0 0 2 2 2 0 Amino acid permease Polysacc_synt_C PF14667.1 KOS21868.1 - 0.5 10.1 12.4 1.3 8.8 2.9 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Wzy_C PF04932.10 KOS21868.1 - 0.54 10.0 3.4 12 5.6 0.7 2.3 2 0 0 2 2 2 0 O-Antigen ligase DUF2207 PF09972.4 KOS21868.1 - 1.6 7.2 4.5 0.91 8.0 0.7 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3357 PF11837.3 KOS21868.1 - 3.6 7.4 5.5 7.8 6.3 0.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF1469 PF07332.6 KOS21868.1 - 5.2 6.8 9.3 9.7 5.9 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF1422 PF07226.6 KOS21868.1 - 6.1 6.6 10.5 1.1 9.0 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) Ank_2 PF12796.2 KOS21869.1 - 1.6e-17 63.5 0.0 3.3e-17 62.5 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KOS21869.1 - 4.9e-17 60.7 0.2 1.4e-12 46.7 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KOS21869.1 - 1.8e-14 53.7 0.2 4.2e-12 46.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS21869.1 - 6.7e-11 41.3 0.0 6.8e-08 32.0 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 KOS21869.1 - 2.2e-10 40.4 0.2 5.5e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TFIIB PF00382.14 KOS21870.1 - 5.9e-31 106.0 0.6 2.5e-19 68.8 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KOS21870.1 - 7.7e-21 74.1 1.0 7.7e-21 74.1 0.7 3.3 4 0 0 4 4 4 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 KOS21870.1 - 5.1e-05 22.8 0.5 0.0085 15.6 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Rtf2 PF04641.7 KOS21870.1 - 0.47 9.5 8.4 0.16 11.1 0.1 2.5 2 0 0 2 2 2 0 Rtf2 RING-finger Pkinase PF00069.20 KOS21871.1 - 0.00041 19.5 0.1 0.0016 17.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Spore_coat_CotO PF14153.1 KOS21871.1 - 0.0019 17.6 4.9 0.0028 17.1 3.4 1.1 1 0 0 1 1 1 1 Spore coat protein CotO APH PF01636.18 KOS21871.1 - 0.015 15.0 0.8 0.36 10.5 0.4 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nop14 PF04147.7 KOS21871.1 - 0.016 13.1 9.9 0.02 12.8 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 KOS21871.1 - 0.035 11.8 1.6 0.044 11.5 1.1 1.0 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 KOS21871.1 - 0.054 13.3 5.3 0.079 12.8 3.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med2 PF11214.3 KOS21871.1 - 2.4 8.2 0.0 2.4 8.2 0.0 2.9 2 1 0 2 2 1 0 Mediator complex subunit 2 YqfQ PF14181.1 KOS21871.1 - 2.7 8.0 12.8 4.2 7.3 8.9 1.2 1 0 0 1 1 1 0 YqfQ-like protein Daxx PF03344.10 KOS21871.1 - 2.7 6.3 13.8 3.7 5.9 9.6 1.1 1 0 0 1 1 1 0 Daxx Family Prothymosin PF03247.9 KOS21871.1 - 2.8 8.1 31.2 5.3 7.2 21.6 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF2201_N PF13203.1 KOS21871.1 - 4.3 6.4 10.0 6.7 5.7 6.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 KOS21871.1 - 5.3 4.9 12.1 7.5 4.4 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3381 PF11861.3 KOS21871.1 - 5.6 6.4 18.4 8.9 5.7 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DDHD PF02862.12 KOS21871.1 - 7.7 6.2 7.5 14 5.4 5.2 1.3 1 0 0 1 1 1 0 DDHD domain RNase_H2-Ydr279 PF09468.5 KOS21871.1 - 8.7 5.4 11.1 14 4.7 7.7 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SQS_PSY PF00494.14 KOS21872.1 - 1.8e-60 204.4 3.3 2.3e-60 204.1 2.3 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Amino_oxidase PF01593.19 KOS21873.1 - 1.5e-19 70.4 0.0 1e-16 61.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KOS21873.1 - 7.2e-17 61.1 0.1 5.8e-16 58.2 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KOS21873.1 - 3.8e-12 45.8 0.4 2.3e-07 30.0 0.4 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KOS21873.1 - 1.3e-07 30.7 1.5 4.6e-07 29.0 1.2 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KOS21873.1 - 2.1e-07 30.9 0.0 5.7e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KOS21873.1 - 1.2e-06 27.2 0.1 0.0002 19.9 0.3 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KOS21873.1 - 1.8e-06 27.2 0.0 2.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KOS21873.1 - 4.3e-06 26.9 0.1 0.00017 21.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KOS21873.1 - 1.4e-05 24.3 0.2 6.3e-05 22.1 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KOS21873.1 - 2.7e-05 23.3 0.0 4.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KOS21873.1 - 0.00051 20.3 1.1 0.0015 18.8 0.7 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KOS21873.1 - 0.0014 17.5 1.8 0.0029 16.5 1.2 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KOS21873.1 - 0.002 17.9 0.2 0.0059 16.3 0.2 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding ApbA PF02558.11 KOS21873.1 - 0.0059 16.0 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 KOS21873.1 - 0.031 12.9 1.2 0.21 10.1 0.8 2.0 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 KOS21873.1 - 0.043 13.4 1.3 0.075 12.6 0.9 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KOS21873.1 - 0.071 12.0 0.4 0.13 11.1 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 KOS21873.1 - 0.077 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 KOS21873.1 - 0.094 12.9 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Asp PF00026.18 KOS21874.1 - 2.1e-72 244.0 6.3 2.5e-72 243.8 4.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KOS21874.1 - 7.4e-05 22.7 1.2 0.00025 21.0 0.2 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KOS21874.1 - 0.003 18.0 0.3 0.17 12.4 0.1 2.7 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 KOS21874.1 - 0.0095 15.4 0.0 0.023 14.2 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal PP2C PF00481.16 KOS21875.1 - 2e-25 89.6 0.0 3.2e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Brix PF04427.13 KOS21876.1 - 1.3e-56 191.3 0.0 1.6e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Brix domain DUF3306 PF11748.3 KOS21876.1 - 6.1 7.5 15.5 0.82 10.3 5.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) CsbD PF05532.7 KOS21877.1 - 6.8e-08 32.0 5.7 0.00076 19.1 0.5 2.2 2 0 0 2 2 2 2 CsbD-like DUF1183 PF06682.7 KOS21878.1 - 0.043 13.4 0.2 0.076 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) PufQ PF05398.6 KOS21878.1 - 0.33 10.9 2.4 0.39 10.7 0.0 2.2 2 0 0 2 2 2 0 PufQ cytochrome subunit Daxx PF03344.10 KOS21880.1 - 1.1 7.6 20.2 1.1 7.6 14.0 1.0 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 KOS21880.1 - 2.2 7.4 15.0 2.2 7.4 10.4 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 KOS21880.1 - 2.9 5.8 21.9 2.9 5.8 15.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 KOS21880.1 - 8.1 5.7 12.8 8 5.7 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNase_PH PF01138.16 KOS21882.1 - 3.5e-11 43.5 0.0 4.1e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KOS21882.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 NUDIX PF00293.23 KOS21883.1 - 1.2e-07 31.4 0.2 1.3e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NEMO PF11577.3 KOS21883.1 - 0.021 14.5 2.4 1.5 8.6 0.1 2.3 1 1 1 2 2 2 0 NF-kappa-B essential modulator NEMO Tox-MPTase3 PF15639.1 KOS21883.1 - 0.054 13.2 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 3 LSM PF01423.17 KOS21884.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 LSM domain Cir_N PF10197.4 KOS21884.1 - 0.52 10.3 3.0 0.68 9.9 2.1 1.2 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Fructosamin_kin PF03881.9 KOS21885.1 - 1.3e-52 178.5 0.0 2.6e-52 177.6 0.0 1.4 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KOS21885.1 - 1.6e-07 31.3 6.4 3.1e-07 30.3 4.4 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Snf7 PF03357.16 KOS21886.1 - 5.9e-33 113.6 5.7 6.8e-33 113.4 4.0 1.0 1 0 0 1 1 1 1 Snf7 AAA PF00004.24 KOS21887.1 - 6.6e-63 210.7 0.0 3.4e-45 153.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS21887.1 - 1.5e-08 34.5 0.1 0.00034 20.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KOS21887.1 - 4.2e-08 32.5 0.0 0.0018 17.3 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KOS21887.1 - 4.6e-08 33.0 0.0 0.0071 16.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KOS21887.1 - 7.2e-08 32.6 5.5 0.00012 22.0 0.1 4.3 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 KOS21887.1 - 1.7e-07 31.4 0.0 0.0079 16.3 0.0 3.9 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KOS21887.1 - 4.2e-07 30.8 0.0 0.044 14.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 KOS21887.1 - 8.6e-06 25.6 0.0 0.00083 19.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 KOS21887.1 - 1e-05 25.8 0.0 0.067 13.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 KOS21887.1 - 3.3e-05 23.8 0.0 0.00017 21.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 KOS21887.1 - 4.7e-05 23.0 0.8 0.012 15.2 0.0 4.1 4 1 1 5 5 4 1 Part of AAA domain Zeta_toxin PF06414.7 KOS21887.1 - 0.00029 20.0 0.0 0.0055 15.8 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.17 KOS21887.1 - 0.00054 20.1 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 KOS21887.1 - 0.0014 17.8 0.2 0.29 10.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KOS21887.1 - 0.0016 17.9 0.1 0.085 12.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF815 PF05673.8 KOS21887.1 - 0.0019 17.2 0.0 1.7 7.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_28 PF13521.1 KOS21887.1 - 0.0023 17.9 0.0 1.4 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KOS21887.1 - 0.0027 17.1 0.4 1.6 8.1 0.1 3.3 2 1 1 3 3 3 1 AAA domain AAA_11 PF13086.1 KOS21887.1 - 0.0056 16.2 0.4 1.3 8.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 KOS21887.1 - 0.015 15.3 0.0 0.36 10.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.10 KOS21887.1 - 0.016 15.0 0.0 0.066 13.0 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 KOS21887.1 - 0.019 14.5 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KOS21887.1 - 0.032 13.8 0.2 2.5 7.7 0.0 3.1 3 0 0 3 3 3 0 NACHT domain Rad17 PF03215.10 KOS21887.1 - 0.041 12.5 0.0 2.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ATP-synt_ab PF00006.20 KOS21887.1 - 0.043 13.3 0.0 0.79 9.1 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_3 PF07726.6 KOS21887.1 - 0.045 13.3 0.0 3.6 7.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KOS21887.1 - 0.047 12.3 0.0 0.46 9.1 0.0 2.0 2 0 0 2 2 2 0 TIP49 C-terminus Arch_ATPase PF01637.13 KOS21887.1 - 0.066 12.9 0.0 8 6.0 0.0 2.8 2 1 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 KOS21887.1 - 0.091 13.0 1.9 1.6 8.9 0.0 3.3 4 1 0 4 4 3 0 ABC transporter Sigma54_activat PF00158.21 KOS21887.1 - 0.12 11.8 0.0 1.3 8.5 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain Dicty_REP PF05086.7 KOS21887.1 - 1.2 6.7 4.3 1.7 6.2 3.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cytochrom_C PF00034.16 KOS21888.1 - 3e-08 34.3 0.1 4.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KOS21888.1 - 1.2e-07 31.8 3.8 1.4e-06 28.3 2.6 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KOS21888.1 - 0.0015 17.9 1.8 0.0045 16.4 0.1 2.3 2 1 1 3 3 3 1 Cytochrome c-550 domain Pyridoxal_deC PF00282.14 KOS21889.1 - 1.9e-57 194.4 0.0 3.6e-48 163.8 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KOS21889.1 - 0.00045 19.0 0.0 0.0041 15.9 0.0 2.0 1 1 1 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KOS21889.1 - 0.029 13.4 0.0 0.081 11.9 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Abhydrolase_3 PF07859.8 KOS21890.1 - 3.3e-36 124.8 0.0 3.2e-25 88.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS21890.1 - 0.018 14.7 0.0 0.088 12.5 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 KOS21890.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2424 PF10340.4 KOS21890.1 - 0.16 10.6 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Ufd2P_core PF10408.4 KOS21891.1 - 6.2e-180 599.5 9.4 8e-180 599.1 6.5 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KOS21891.1 - 2.8e-22 78.4 1.2 1.1e-21 76.5 0.8 2.1 1 0 0 1 1 1 1 U-box domain LOH1CR12 PF10158.4 KOS21891.1 - 0.098 12.4 1.6 0.43 10.3 0.3 2.4 2 0 0 2 2 2 0 Tumour suppressor protein Fungal_trans PF04082.13 KOS21892.1 - 6.8e-25 87.4 0.2 1.4e-24 86.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS21892.1 - 5.2e-08 32.6 13.7 1.1e-07 31.6 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shugoshin_N PF07558.6 KOS21892.1 - 0.06 13.0 1.2 0.11 12.2 0.9 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region YIF1 PF03878.10 KOS21892.1 - 0.24 10.5 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 YIF1 PBP_like_2 PF12849.2 KOS21893.1 - 6.2e-08 32.4 2.3 7.9e-08 32.1 1.6 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.1 KOS21893.1 - 0.00016 21.3 0.3 0.0051 16.4 0.2 2.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.1 KOS21893.1 - 0.0075 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein BLIP PF07467.6 KOS21893.1 - 0.066 12.8 0.4 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 Beta-lactamase inhibitor (BLIP) SBP_bac_1 PF01547.20 KOS21893.1 - 0.069 12.8 5.6 0.45 10.2 0.0 2.6 2 1 0 3 3 3 0 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.1 KOS21893.1 - 0.14 11.8 5.3 0.061 13.0 0.5 2.0 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein zf-TRAF PF02176.13 KOS21894.1 - 5.7e-11 42.6 21.5 2.2e-08 34.3 1.9 3.5 2 1 1 3 3 3 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 KOS21894.1 - 4e-09 36.3 6.9 4e-09 36.3 4.8 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS21894.1 - 2.9e-08 33.2 6.1 2.9e-08 33.2 4.2 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KOS21894.1 - 6.7e-08 32.2 7.4 6.7e-08 32.2 5.1 3.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KOS21894.1 - 3.7e-07 29.8 6.4 3.7e-07 29.8 4.4 3.2 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KOS21894.1 - 1.5e-06 27.7 2.6 1.5e-06 27.7 1.8 3.1 2 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS21894.1 - 3.4e-06 26.6 3.5 3.4e-06 26.6 2.4 3.2 2 1 1 3 3 2 1 zinc-RING finger domain zf-Nse PF11789.3 KOS21894.1 - 0.00076 18.9 9.0 0.0014 18.1 1.8 2.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Sina PF03145.11 KOS21894.1 - 0.0034 17.0 15.9 0.018 14.7 1.4 3.1 2 1 0 3 3 3 2 Seven in absentia protein family zf-RING_UBOX PF13445.1 KOS21894.1 - 0.011 15.4 5.7 0.011 15.4 4.0 2.3 3 0 0 3 3 2 0 RING-type zinc-finger zf-Apc11 PF12861.2 KOS21894.1 - 0.012 15.3 1.3 0.012 15.3 0.9 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 KOS21894.1 - 0.11 12.2 3.1 0.31 10.8 2.2 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Ald_Xan_dh_C2 PF02738.13 KOS21895.1 - 2e-192 640.3 0.2 3e-192 639.7 0.1 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KOS21895.1 - 9.6e-46 155.3 0.0 2.1e-45 154.2 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 KOS21895.1 - 1.4e-31 108.7 0.0 3.2e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 KOS21895.1 - 1.7e-30 104.9 1.3 7.2e-30 102.9 0.1 2.6 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 KOS21895.1 - 1e-28 99.0 0.1 2.5e-28 97.8 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 KOS21895.1 - 1.5e-07 31.0 2.2 1.9e-07 30.7 0.1 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Aminotran_1_2 PF00155.16 KOS21896.1 - 3.1e-57 194.1 0.0 3.9e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KOS21896.1 - 3e-06 26.5 0.0 4.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KOS21896.1 - 0.00013 21.2 0.0 0.00019 20.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KOS21896.1 - 0.00027 19.3 0.0 0.00072 17.9 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KOS21896.1 - 0.039 12.6 0.0 0.075 11.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V SPO22 PF08631.5 KOS21897.1 - 1.3e-41 142.5 0.0 1.8e-40 138.8 0.0 2.2 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 KOS21897.1 - 0.0026 17.6 3.6 0.022 14.6 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Latarcin PF10279.4 KOS21897.1 - 0.11 12.7 0.0 6.1 7.0 0.0 2.8 2 0 0 2 2 2 0 Latarcin precursor DUF104 PF01954.11 KOS21898.1 - 0.046 13.7 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF104 PAS PF00989.19 KOS21898.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold MerR PF00376.18 KOS21898.1 - 0.21 11.2 0.7 59 3.3 0.0 3.3 3 0 0 3 3 3 0 MerR family regulatory protein CENP-T PF15511.1 KOS21899.1 - 5.4e-99 332.2 19.5 6.4e-58 196.9 11.6 3.1 3 1 1 4 4 4 2 Centromere kinetochore component CENP-T CENP-S PF15630.1 KOS21899.1 - 2.1e-08 34.2 0.0 3.5e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 KOS21899.1 - 9.3e-07 28.8 0.0 1.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KOS21899.1 - 0.00068 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KOS21899.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated dsDNA_bind PF01984.15 KOS21901.1 - 5.4e-33 113.1 5.6 6.4e-33 112.9 3.9 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Fes1 PF08609.5 KOS21901.1 - 0.1 13.1 1.5 0.35 11.3 0.1 2.0 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 Imm7 PF15588.1 KOS21901.1 - 0.13 12.3 0.6 0.13 12.3 0.4 1.5 2 0 0 2 2 2 0 Immunity protein 7 DUF4615 PF15393.1 KOS21901.1 - 0.16 12.1 1.7 0.29 11.3 1.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) HWE_HK PF07536.9 KOS21901.1 - 0.6 10.5 4.1 0.29 11.6 0.8 2.0 2 1 0 2 2 2 0 HWE histidine kinase Alb1 PF09135.6 KOS21901.1 - 3.4 8.2 6.1 50 4.5 3.8 2.5 1 1 1 2 2 2 0 Alb1 ApbA_C PF08546.6 KOS21902.1 - 1.7e-15 57.1 0.0 3.1e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KOS21902.1 - 1.9e-07 30.6 0.0 4.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF4013 PF13197.1 KOS21903.1 - 0.00026 20.3 6.9 0.00037 19.8 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) Coq4 PF05019.8 KOS21904.1 - 1.2e-91 305.5 0.0 1.4e-91 305.3 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 UBX PF00789.15 KOS21905.1 - 8.8e-12 44.9 0.0 1.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain VIT1 PF01988.14 KOS21905.1 - 0.18 11.2 1.9 0.73 9.2 1.3 2.0 1 1 0 1 1 1 0 VIT family Ycf1 PF05758.7 KOS21905.1 - 0.34 8.5 2.2 0.44 8.2 1.5 1.1 1 0 0 1 1 1 0 Ycf1 RRM_3 PF08777.6 KOS21905.1 - 0.77 9.6 10.5 63 3.4 0.0 3.2 3 0 0 3 3 3 0 RNA binding motif SURF1 PF02104.10 KOS21906.1 - 1.1e-62 211.6 0.1 1.3e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Sas10_Utp3 PF04000.10 KOS21907.1 - 8.2e-16 57.9 0.5 8.2e-16 57.9 0.4 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family RNA_polI_A14 PF08203.6 KOS21907.1 - 0.11 12.6 2.1 1.3 9.3 0.0 2.7 2 1 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 RTC_insert PF05189.8 KOS21907.1 - 0.38 10.7 3.0 8.1 6.5 2.0 2.2 1 1 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain PYC_OADA PF02436.13 KOS21907.1 - 0.54 9.6 3.2 1.2 8.4 0.0 2.1 1 1 1 2 2 2 0 Conserved carboxylase domain DUF2052 PF09747.4 KOS21907.1 - 0.78 9.6 4.6 1.1 9.1 3.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) AKAP7_RIRII_bdg PF10470.4 KOS21907.1 - 0.83 9.5 4.0 5.6 6.8 0.9 2.5 2 1 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein DUF2076 PF09849.4 KOS21908.1 - 1.7e-09 38.0 4.1 2e-09 37.8 2.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 KOS21908.1 - 0.0025 17.6 2.7 0.0032 17.3 0.8 1.8 1 1 1 2 2 2 2 CHCH domain COX6B PF02297.12 KOS21908.1 - 0.024 14.6 1.4 0.036 14.0 1.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb GCK PF07802.6 KOS21908.1 - 0.03 14.4 0.5 0.046 13.8 0.3 1.4 1 1 0 1 1 1 0 GCK domain COX17 PF05051.8 KOS21908.1 - 0.16 12.0 1.0 0.62 10.1 0.0 2.0 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Nucleoporin_FG PF13634.1 KOS21908.1 - 2.3 8.4 10.9 4 7.6 7.5 1.4 1 1 0 1 1 1 0 Nucleoporin FG repeat region DPBB_1 PF03330.13 KOS21909.1 - 1e-08 35.0 0.1 3.4e-08 33.3 0.1 2.1 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 KOS21909.1 - 0.0082 16.1 0.0 0.01 15.8 0.0 1.3 1 1 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 KOS21909.1 - 0.013 15.1 0.3 0.021 14.4 0.2 1.4 1 1 0 1 1 1 0 Barwin family 5_nucleotid_C PF02872.13 KOS21910.1 - 1.4e-32 112.7 0.0 2.3e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KOS21910.1 - 0.00016 21.0 0.0 0.00036 19.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Alginate_lyase PF05426.7 KOS21911.1 - 5.3e-87 291.6 0.1 6.4e-87 291.3 0.1 1.1 1 0 0 1 1 1 1 Alginate lyase CwfJ_C_1 PF04677.10 KOS21912.1 - 6.2e-22 77.5 0.0 1e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KOS21912.1 - 9.4e-22 77.3 0.0 2.1e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Abhydrolase_5 PF12695.2 KOS21913.1 - 0.0015 18.2 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KOS21913.1 - 0.017 14.3 0.0 0.026 13.8 0.0 1.4 1 1 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KOS21913.1 - 0.092 11.9 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family FGGY_C PF02782.11 KOS21914.1 - 8.5e-72 240.9 1.2 1.5e-71 240.1 0.8 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KOS21914.1 - 1.1e-64 218.1 0.0 1.3e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Fungal_trans PF04082.13 KOS21915.1 - 7.2e-19 67.6 0.0 1.5e-18 66.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS21915.1 - 3.9e-08 33.0 9.3 8.1e-08 32.0 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1127 PF06568.6 KOS21915.1 - 0.86 9.0 7.8 5.9 6.3 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) DAO PF01266.19 KOS21916.1 - 2.1e-49 168.3 1.2 2.1e-49 168.3 0.8 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KOS21916.1 - 0.00024 20.3 2.7 0.00087 18.4 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KOS21916.1 - 0.00029 20.5 0.1 0.00054 19.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KOS21916.1 - 0.00068 18.5 5.9 0.035 12.9 1.1 2.6 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.9 KOS21916.1 - 0.0022 17.8 0.1 0.0077 16.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KOS21916.1 - 0.0029 16.5 0.1 0.072 11.9 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KOS21916.1 - 0.0043 17.0 0.4 0.014 15.4 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KOS21916.1 - 0.017 13.6 0.4 0.029 12.8 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein GDI PF00996.13 KOS21916.1 - 0.028 12.7 0.0 0.043 12.1 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Lycopene_cycl PF05834.7 KOS21916.1 - 0.037 12.9 0.8 0.23 10.3 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_10 PF13460.1 KOS21916.1 - 0.042 13.8 0.1 0.13 12.2 0.1 1.9 1 0 0 1 1 1 0 NADH(P)-binding Thi4 PF01946.12 KOS21916.1 - 0.15 11.1 0.6 0.41 9.7 0.0 1.9 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.1 KOS21916.1 - 0.24 10.2 0.0 4.8 6.0 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) MIP PF00230.15 KOS21917.1 - 3.7e-51 173.7 8.9 4.7e-51 173.4 6.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein PRA1 PF03208.14 KOS21917.1 - 0.054 12.8 0.2 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 PRA1 family protein FAD_binding_2 PF00890.19 KOS21918.1 - 1.4e-91 307.4 0.0 1.7e-91 307.2 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KOS21918.1 - 1.6e-05 24.8 0.2 0.00029 20.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KOS21918.1 - 7.3e-05 21.9 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KOS21918.1 - 0.00033 20.6 0.0 0.041 13.7 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KOS21918.1 - 0.00089 18.4 0.0 0.0027 16.8 0.0 1.7 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KOS21918.1 - 0.0032 16.0 0.7 0.19 10.1 0.0 2.5 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 KOS21918.1 - 0.0042 16.0 0.0 0.0089 14.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KOS21918.1 - 0.011 14.6 0.9 0.015 14.2 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KOS21918.1 - 0.013 15.3 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Transp_cyt_pur PF02133.10 KOS21920.1 - 2.6e-80 270.1 31.5 1e-72 245.1 15.8 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.13 KOS21921.1 - 8.9e-26 90.3 0.1 1.6e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS21921.1 - 1.9e-05 24.4 5.7 3.6e-05 23.5 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thi4 PF01946.12 KOS21922.1 - 5e-103 343.1 0.0 6.1e-103 342.8 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KOS21922.1 - 5.8e-07 28.7 0.1 8.4e-07 28.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KOS21922.1 - 1.3e-05 24.3 0.1 5.1e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KOS21922.1 - 0.00026 20.9 0.3 0.00069 19.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KOS21922.1 - 0.0012 18.6 1.2 0.0022 17.7 0.0 2.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KOS21922.1 - 0.01 15.9 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KOS21922.1 - 0.01 15.7 0.5 0.021 14.7 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KOS21922.1 - 0.079 11.9 0.1 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KOS21922.1 - 0.12 10.7 0.3 0.18 10.2 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 KOS21922.1 - 0.31 9.8 5.2 0.18 10.5 0.4 2.7 3 1 1 4 4 4 0 FAD binding domain DUF917 PF06032.7 KOS21923.1 - 4.5e-112 374.0 0.0 1.3e-111 372.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KOS21923.1 - 8.7e-47 159.5 2.1 2.3e-44 151.6 0.7 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KOS21923.1 - 1.8e-30 105.7 0.0 2.3e-27 95.6 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 KOS21923.1 - 8.4e-06 24.3 0.8 0.0081 14.5 0.0 2.8 3 0 0 3 3 3 2 MutL protein StbA PF06406.6 KOS21923.1 - 0.011 14.7 0.0 1.5 7.6 0.0 2.6 2 0 0 2 2 2 0 StbA protein BcrAD_BadFG PF01869.15 KOS21923.1 - 0.18 11.0 3.1 2.1 7.5 0.0 2.8 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 KOS21923.1 - 2.1 8.2 5.8 6.1 6.7 0.0 3.2 4 0 0 4 4 4 0 Cell division protein FtsA Pro_CA PF00484.14 KOS21924.1 - 2.3e-50 170.5 0.0 3e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Glyco_hydro_cc PF11790.3 KOS21926.1 - 3.7e-67 226.2 0.2 4.3e-67 226.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fip1 PF05182.8 KOS21926.1 - 0.0044 16.2 0.6 0.0044 16.2 0.4 2.0 2 0 0 2 2 2 1 Fip1 motif Cation_ATPase_C PF00689.16 KOS21927.1 - 3.9e-34 117.7 1.9 3.9e-34 117.7 1.3 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KOS21927.1 - 3.8e-30 105.8 0.0 8.8e-30 104.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KOS21927.1 - 1.9e-14 53.2 4.2 1.9e-14 53.2 2.9 1.8 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 KOS21927.1 - 1.5e-12 48.1 0.0 2.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KOS21927.1 - 3e-07 30.2 0.2 2.8e-05 23.8 0.2 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase p450 PF00067.17 KOS21929.1 - 1.3e-57 195.4 0.0 1.2e-44 152.6 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 JmjC PF02373.17 KOS21930.1 - 9.2e-38 129.0 0.2 2e-37 127.9 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.1 KOS21930.1 - 4.6e-21 74.7 3.9 1.3e-20 73.3 2.7 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KOS21930.1 - 1.6e-20 73.1 3.2 3e-20 72.2 2.2 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.12 KOS21930.1 - 1.6e-13 49.9 0.5 1e-12 47.3 0.4 2.3 2 0 0 2 2 2 1 jmjN domain RXT2_N PF08595.6 KOS21930.1 - 0.092 12.5 16.1 0.063 13.0 3.1 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal TLP-20 PF06088.6 KOS21930.1 - 9.9 5.7 7.5 10 5.7 1.5 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Hamartin PF04388.7 KOS21931.1 - 0.048 12.3 17.6 0.071 11.7 12.2 1.3 1 0 0 1 1 1 0 Hamartin protein AAA_23 PF13476.1 KOS21931.1 - 0.13 12.5 12.5 0.025 14.8 4.4 2.2 2 0 0 2 2 2 0 AAA domain Baculo_PP31 PF05311.6 KOS21931.1 - 1.5 8.0 12.2 0.046 12.9 4.1 1.7 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) DUF4557 PF15101.1 KOS21931.1 - 8.1 6.2 26.8 22 4.7 18.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Shugoshin_N PF07558.6 KOS21932.1 - 6.3e-07 29.0 6.3 1.3e-06 28.0 4.1 1.8 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Mod_r PF07200.8 KOS21932.1 - 0.014 15.3 1.7 0.025 14.5 1.2 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DASH_Dad2 PF08654.5 KOS21933.1 - 9.5e-27 93.0 0.3 1.1e-26 92.8 0.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.17 KOS21933.1 - 0.068 13.1 0.1 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain NUC173 PF08161.7 KOS21934.1 - 1.7e-77 259.2 0.2 1.8e-76 255.9 0.0 2.7 3 0 0 3 3 3 1 NUC173 domain HEAT PF02985.17 KOS21934.1 - 0.00021 21.0 0.9 0.2 11.7 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 KOS21934.1 - 0.0015 18.7 7.5 0.43 10.9 0.3 4.5 4 1 0 4 4 4 2 HEAT repeats Metallophos_2 PF12850.2 KOS21935.1 - 1.4e-14 54.2 0.0 1.7e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KOS21935.1 - 0.00084 18.7 0.1 0.02 14.3 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase OB_NTP_bind PF07717.11 KOS21937.1 - 1.1e-23 83.2 0.0 1.9e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KOS21937.1 - 9.5e-21 73.7 0.1 1.9e-20 72.7 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KOS21937.1 - 5.5e-13 48.5 0.0 1.4e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KOS21937.1 - 0.00012 22.1 0.0 0.00037 20.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KOS21937.1 - 0.0014 18.1 0.5 0.0054 16.2 0.3 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KOS21937.1 - 0.0053 15.6 0.0 0.013 14.3 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 KOS21937.1 - 0.05 13.3 0.9 0.17 11.6 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain Zeta_toxin PF06414.7 KOS21937.1 - 0.063 12.3 0.0 0.16 11.0 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin cobW PF02492.14 KOS21937.1 - 0.065 12.6 0.1 0.37 10.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KOS21937.1 - 0.066 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KOS21937.1 - 0.066 13.1 0.1 11 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KOS21937.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KOS21937.1 - 0.14 12.5 0.0 0.31 11.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain COesterase PF00135.23 KOS21938.1 - 1.6e-61 208.6 0.0 2.4e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KOS21938.1 - 4.4e-06 26.4 3.1 0.0082 15.7 0.2 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold SKG6 PF08693.5 KOS21939.1 - 4.9e-06 25.7 0.4 4.9e-06 25.7 0.3 2.9 3 0 0 3 3 3 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 KOS21939.1 - 0.021 14.5 0.7 0.021 14.5 0.5 2.6 2 1 0 2 2 2 0 TMEM154 protein family DUF912 PF06024.7 KOS21939.1 - 0.081 12.9 1.0 1.3e+02 2.7 4.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PgaD PF13994.1 KOS21939.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein Ribosomal_L13 PF00572.13 KOS21940.1 - 1.3e-27 96.3 0.1 2.7e-27 95.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L13 TPR_11 PF13414.1 KOS21941.1 - 3.1e-10 39.5 1.7 3.2e-06 26.6 0.0 2.8 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 KOS21941.1 - 1.3e-07 30.9 6.7 0.00015 21.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS21941.1 - 0.00031 21.0 0.1 0.005 17.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KOS21941.1 - 0.00047 20.7 8.4 0.0023 18.5 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KOS21941.1 - 0.00069 19.1 2.6 0.083 12.5 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KOS21941.1 - 0.00096 19.0 0.1 0.095 12.6 0.0 3.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 KOS21941.1 - 0.015 15.6 3.9 0.17 12.3 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KOS21941.1 - 0.024 15.2 0.1 0.024 15.2 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 KOS21941.1 - 0.21 11.4 1.7 8.7 6.3 0.1 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 KOS21941.1 - 0.64 9.9 4.5 0.49 10.2 0.3 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Adap_comp_sub PF00928.16 KOS21944.1 - 7.8e-75 251.3 0.0 1e-74 250.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KOS21944.1 - 4e-05 23.3 0.3 7.2e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Glyco_hydro_18 PF00704.23 KOS21945.1 - 3e-10 40.0 0.1 8.2e-10 38.6 0.0 1.7 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 KH_1 PF00013.24 KOS21946.1 - 1.8e-09 37.0 0.1 3.7e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KOS21946.1 - 5.3e-06 25.9 0.2 1.2e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 KH domain MULE PF10551.4 KOS21947.1 - 4e-10 39.7 0.0 1.5e-09 37.9 0.0 2.1 1 1 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 KOS21947.1 - 1.1e-05 25.8 0.2 2.4e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Glutaredoxin PF00462.19 KOS21948.1 - 2e-20 72.5 0.0 2.9e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 KOS21948.1 - 2e-05 24.7 0.1 3e-05 24.1 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.1 KOS21948.1 - 5.2e-05 23.3 0.0 6.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.1 KOS21948.1 - 0.0048 16.9 0.2 0.54 10.2 0.1 2.1 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_9 PF14595.1 KOS21948.1 - 0.0057 16.2 0.1 0.0095 15.4 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 KOS21948.1 - 0.013 15.1 0.2 0.37 10.3 0.1 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF953 PF06110.6 KOS21948.1 - 0.013 14.9 0.2 0.075 12.4 0.1 1.9 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 KOS21948.1 - 0.035 13.8 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.1 KOS21948.1 - 0.038 14.1 0.1 0.07 13.2 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like DUF836 PF05768.9 KOS21948.1 - 0.05 13.8 0.0 0.061 13.5 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Redoxin PF08534.5 KOS21948.1 - 0.087 12.3 0.4 0.11 12.0 0.3 1.3 1 1 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.1 KOS21948.1 - 0.093 12.7 0.1 0.15 12.0 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like BAG PF02179.11 KOS21949.1 - 4e-18 65.2 0.0 7.7e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 KOS21949.1 - 7.8e-06 25.2 0.0 1.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family MTH865 PF07747.6 KOS21949.1 - 0.098 12.2 0.1 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 MTH865-like family Rad60-SLD PF11976.3 KOS21949.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Abhydrolase_5 PF12695.2 KOS21951.1 - 2.3e-05 24.1 6.8 0.00041 20.1 4.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KOS21951.1 - 0.0001 21.9 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KOS21951.1 - 0.0014 18.5 7.7 0.0077 16.1 5.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KOS21951.1 - 0.0029 16.9 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.15 KOS21951.1 - 0.023 14.9 0.0 0.052 13.7 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 KOS21951.1 - 0.043 13.4 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.7 KOS21951.1 - 0.15 11.3 0.0 0.68 9.2 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2305 PF10230.4 KOS21951.1 - 0.21 10.9 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Asp PF00026.18 KOS21952.1 - 8.8e-56 189.4 0.0 1.1e-55 189.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KOS21952.1 - 1.1e-08 35.1 0.1 2.7e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KOS21952.1 - 1.8e-06 28.3 0.8 0.00077 19.9 0.1 3.9 3 1 0 3 3 3 1 Aspartyl protease Abhydrolase_3 PF07859.8 KOS21953.1 - 2.4e-22 79.5 0.4 1.5e-21 76.9 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KOS21953.1 - 8.8e-08 31.1 0.0 1.7e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KOS21953.1 - 0.019 14.6 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_18 PF12847.2 KOS21954.1 - 1.3e-09 38.5 0.0 2.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS21954.1 - 2e-09 37.3 0.0 3.4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS21954.1 - 2.9e-09 37.2 0.0 5.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS21954.1 - 3.9e-09 36.8 0.0 8.8e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS21954.1 - 1.5e-08 34.3 0.0 2.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS21954.1 - 1.8e-06 27.9 0.0 7.7e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS21954.1 - 6.7e-06 26.5 0.0 1.4e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KOS21954.1 - 0.0022 17.7 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KOS21954.1 - 0.056 12.4 0.0 8.4 5.3 0.0 2.4 2 1 0 2 2 2 0 Putative methyltransferase MTS PF05175.9 KOS21954.1 - 0.085 12.2 0.0 0.21 10.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 KOS21954.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Complex1_LYR_2 PF13233.1 KOS21955.1 - 1.6e-06 28.5 0.1 1.8e-06 28.3 0.1 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KOS21955.1 - 9.8e-06 25.2 0.5 1.2e-05 24.9 0.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KOS21955.1 - 0.00016 21.8 0.5 0.00018 21.6 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Ras PF00071.17 KOS21956.1 - 3e-50 169.7 0.0 3.5e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS21956.1 - 3.1e-17 63.1 0.0 5e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS21956.1 - 5e-06 25.8 0.0 6.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KOS21956.1 - 0.00084 18.8 0.0 0.0027 17.1 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ank_5 PF13857.1 KOS21958.1 - 4.3e-05 23.6 0.0 0.00015 21.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KOS21958.1 - 0.045 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Git3 PF11710.3 KOS21959.1 - 1.9e-20 73.3 9.3 4e-20 72.2 6.4 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KOS21959.1 - 3.5e-12 46.0 1.1 3.5e-12 46.0 0.7 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 KOS21959.1 - 0.001 18.0 9.8 0.0022 16.9 6.8 1.6 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3_C PF11970.3 KOS21959.1 - 0.0012 18.5 3.3 0.0015 18.2 0.1 2.6 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Mpv17_PMP22 PF04117.7 KOS21960.1 - 7e-12 44.8 0.2 1.4e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.11 KOS21962.1 - 7.1e-32 110.4 29.7 7.1e-32 110.4 20.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1509 PF07420.6 KOS21962.1 - 5.1 6.2 9.8 7.4 5.7 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) NmrA PF05368.8 KOS21963.1 - 4.1e-48 163.6 1.3 5.3e-48 163.3 0.9 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KOS21963.1 - 2.9e-11 43.7 8.5 2.9e-11 43.7 5.9 1.8 1 1 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KOS21963.1 - 1.3e-05 24.0 0.1 2e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Fasciclin PF02469.17 KOS21964.1 - 4.3e-42 143.1 0.0 7.1e-23 80.9 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Amidohydro_2 PF04909.9 KOS21965.1 - 1.4e-40 139.6 0.5 1.7e-40 139.3 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF2407_C PF13373.1 KOS21965.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain Flavoprotein PF02441.14 KOS21966.1 - 7e-37 125.9 0.1 9.3e-37 125.5 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein dCMP_cyt_deam_1 PF00383.17 KOS21968.1 - 1.2e-13 50.5 0.0 1.5e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region OTT_1508_deam PF14441.1 KOS21968.1 - 0.0052 16.6 0.0 0.0057 16.4 0.0 1.1 1 0 0 1 1 1 1 OTT_1508-like deaminase Bd3614-deam PF14439.1 KOS21968.1 - 0.0066 16.3 4.2 0.77 9.6 0.0 2.3 1 1 1 2 2 2 2 Bd3614-like deaminase Dioxygenase_C PF00775.16 KOS21969.1 - 5.6e-57 191.9 0.0 7.2e-57 191.5 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KOS21969.1 - 1.1e-09 38.1 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KOS21969.1 - 5.3e-06 26.4 0.0 2.9e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 KOS21969.1 - 0.0083 16.1 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) FAD_binding_3 PF01494.14 KOS21970.1 - 2.9e-11 43.0 0.2 5e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KOS21970.1 - 1e-10 41.4 0.8 2.9e-10 40.0 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KOS21970.1 - 4.8e-07 29.0 4.0 6.7e-07 28.5 2.3 1.5 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KOS21970.1 - 2.1e-06 27.1 0.0 2.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KOS21970.1 - 4.4e-06 25.7 0.8 6e-06 25.3 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KOS21970.1 - 1.7e-05 24.7 0.1 2.8e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KOS21970.1 - 5e-05 22.5 0.2 0.0062 15.6 0.0 2.4 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.17 KOS21970.1 - 0.00017 20.5 1.0 0.00023 20.1 0.7 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KOS21970.1 - 0.00046 19.2 0.2 0.00073 18.5 0.1 1.3 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 KOS21970.1 - 0.001 19.4 1.2 0.0021 18.4 0.8 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KOS21970.1 - 0.0042 15.6 1.2 0.0059 15.1 0.8 1.1 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 KOS21970.1 - 0.022 13.3 1.2 0.031 12.9 0.8 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 KOS21970.1 - 0.033 13.2 0.4 0.052 12.6 0.3 1.2 1 0 0 1 1 1 0 Thi4 family Rossmann-like PF10727.4 KOS21970.1 - 0.038 13.7 0.2 0.066 12.9 0.1 1.3 1 0 0 1 1 1 0 Rossmann-like domain Pyr_redox_3 PF13738.1 KOS21970.1 - 0.058 13.4 0.6 0.087 12.8 0.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS21970.1 - 0.076 12.7 0.6 0.53 10.0 0.3 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 KOS21970.1 - 0.15 11.6 0.3 0.23 10.9 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.11 KOS21971.1 - 7.9e-24 84.0 29.4 7.9e-24 84.0 20.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_stabilise PF11134.3 KOS21972.1 - 0.15 10.5 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Phage stabilisation protein Myb_DNA-bind_3 PF12776.2 KOS21973.1 - 5.5e-20 71.7 0.2 6.5e-20 71.5 0.1 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain adh_short PF00106.20 KOS21974.1 - 5e-24 85.0 0.0 6.6e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS21974.1 - 8.1e-10 38.8 0.0 1e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS21974.1 - 4.5e-08 32.9 0.0 9.8e-08 31.8 0.0 1.5 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.13 KOS21974.1 - 0.0017 18.0 0.1 0.0038 16.8 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 KOS21974.1 - 0.029 14.1 0.1 0.067 12.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TrkA_N PF02254.13 KOS21974.1 - 0.063 13.2 0.2 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_31 PF13847.1 KOS21974.1 - 0.098 12.2 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KOS21974.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF1776 PF08643.5 KOS21974.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glycos_transf_1 PF00534.15 KOS21975.1 - 1e-32 112.8 0.0 1.6e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KOS21975.1 - 7.4e-18 65.0 0.1 1.5e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KOS21975.1 - 5.8e-15 55.7 3.8 5.8e-15 55.7 2.6 2.2 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KOS21975.1 - 2e-10 40.8 0.0 4.3e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KOS21975.1 - 4e-08 33.1 0.0 1.5e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 UDPG_MGDP_dh_N PF03721.9 KOS21976.1 - 4.9e-48 162.9 0.0 1.2e-30 106.2 0.0 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 KOS21976.1 - 6.5e-32 109.6 0.0 1.3e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 KOS21976.1 - 7.3e-23 80.7 0.0 1.6e-17 63.5 0.0 3.3 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 KOS21976.1 - 0.017 14.8 0.0 4.6 6.9 0.0 3.4 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 KOS21976.1 - 0.019 13.9 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 KOS21976.1 - 0.044 13.6 0.0 1.8 8.4 0.0 2.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 4HBT_2 PF13279.1 KOS21977.1 - 5.7e-16 59.0 0.0 9.2e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily NAD_binding_10 PF13460.1 KOS21978.1 - 1.8e-06 28.0 1.5 3.9e-06 26.9 1.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding FmdA_AmdA PF03069.10 KOS21979.1 - 9.9e-129 429.2 0.0 1.2e-128 428.8 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family CoA_binding PF02629.14 KOS21981.1 - 7.7e-27 93.6 6.2 1.7e-26 92.5 0.8 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KOS21981.1 - 3.3e-23 81.9 0.7 5.9e-23 81.1 0.5 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KOS21981.1 - 2.3e-09 36.9 0.1 3.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KOS21981.1 - 0.00029 20.9 0.1 0.00088 19.4 0.1 1.8 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 KOS21981.1 - 0.04 14.4 0.1 0.078 13.4 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Radical_SAM PF04055.16 KOS21982.1 - 1.6e-16 60.9 0.1 7.9e-16 58.6 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KOS21982.1 - 2.9e-11 43.2 0.0 7.9e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KOS21982.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Adaptin_N PF01602.15 KOS21983.1 - 2.4e-114 382.5 0.1 3.3e-114 382.1 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KOS21983.1 - 6.4e-57 191.6 2.7 1.4e-56 190.5 1.9 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KOS21983.1 - 4.5e-15 55.6 2.5 6.2e-05 23.1 0.0 5.8 2 1 2 4 4 4 4 HEAT repeats DUF3730 PF12530.3 KOS21983.1 - 0.00082 19.3 2.3 0.0044 16.9 0.4 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3730) HEAT_PBS PF03130.11 KOS21983.1 - 0.0012 19.1 0.1 5.9 7.6 0.0 4.1 3 0 0 3 3 3 2 PBS lyase HEAT-like repeat Arm PF00514.18 KOS21983.1 - 0.0059 16.3 0.0 2.2 8.2 0.0 4.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KOS21983.1 - 0.35 11.0 12.3 0.36 11.0 0.1 5.2 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.1 KOS21983.1 - 0.46 11.0 8.5 0.18 12.3 0.5 3.3 3 0 0 3 3 3 0 HEAT-like repeat Pyr_redox_3 PF13738.1 KOS21985.1 - 1.7e-15 57.6 0.0 4.8e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KOS21985.1 - 1e-13 50.3 0.1 1.7e-13 49.6 0.1 1.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KOS21985.1 - 1.2e-07 31.0 0.1 0.00022 20.2 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KOS21985.1 - 1.4e-06 28.2 0.0 3.4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KOS21985.1 - 0.0072 15.2 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase ATP12 PF07542.6 KOS21986.1 - 1.9e-28 98.8 0.2 5.2e-28 97.4 0.0 1.7 2 0 0 2 2 2 1 ATP12 chaperone protein Exo_endo_phos PF03372.18 KOS21987.1 - 5.7e-26 91.9 0.1 7.7e-26 91.5 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KOS21987.1 - 4e-13 48.6 10.3 4e-07 29.5 0.2 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS21987.1 - 0.00045 19.9 4.8 0.0062 16.2 0.1 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KOS21987.1 - 0.0008 19.1 8.3 0.18 11.9 0.0 4.7 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.1 KOS21987.1 - 0.029 14.3 0.7 0.7 10.1 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich repeat LRR_7 PF13504.1 KOS21987.1 - 1.2 9.5 4.9 29 5.4 0.0 3.6 4 0 0 4 4 4 0 Leucine rich repeat adh_short PF00106.20 KOS21988.1 - 9.5e-18 64.6 0.1 1.3e-17 64.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS21988.1 - 1.4e-10 41.1 0.1 3.1e-10 40.0 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KOS21988.1 - 1.2e-06 28.1 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KOS21988.1 - 0.00014 20.6 0.0 0.00017 20.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KOS21988.1 - 0.0013 18.8 0.1 0.002 18.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KOS21988.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.13 KOS21988.1 - 0.037 14.0 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Mito_carr PF00153.22 KOS21989.1 - 1.6e-16 59.7 1.5 1.6e-10 40.5 0.0 3.5 2 1 0 2 2 2 2 Mitochondrial carrier protein WW PF00397.21 KOS21992.1 - 5.2e-07 29.4 0.2 1e-06 28.4 0.2 1.5 1 0 0 1 1 1 1 WW domain Peptidase_M16 PF00675.15 KOS21993.1 - 1.1e-18 67.3 0.0 2.3e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KOS21993.1 - 2.7e-14 53.2 0.0 5.2e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain LsmAD PF06741.8 KOS21994.1 - 3.2e-19 68.7 2.6 3.2e-19 68.7 1.8 2.3 2 0 0 2 2 2 1 LsmAD domain Mito_carr PF00153.22 KOS21995.1 - 6.2e-29 99.5 0.4 7.2e-15 54.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpc82 PF05645.8 KOS21996.1 - 6.6e-53 179.8 0.0 8.5e-52 176.2 0.0 2.4 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 KOS21996.1 - 7e-13 48.2 0.8 4e-11 42.6 0.1 3.2 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KOS21996.1 - 0.00045 19.6 0.1 0.1 12.0 0.0 2.8 2 0 0 2 2 2 2 TFIIE alpha subunit RcsC PF09456.5 KOS21996.1 - 0.092 12.3 0.1 12 5.5 0.0 2.6 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) MutS_II PF05188.12 KOS21996.1 - 0.11 12.5 0.3 0.31 11.1 0.2 1.7 1 0 0 1 1 1 0 MutS domain II FEZ PF07763.8 KOS21997.1 - 0.023 14.4 2.4 0.049 13.3 1.6 1.5 1 0 0 1 1 1 0 FEZ-like protein Pga1 PF10333.4 KOS21999.1 - 0.007 16.0 0.0 0.012 15.2 0.0 1.4 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator DUF1509 PF07420.6 KOS21999.1 - 0.0086 15.3 0.8 0.012 14.9 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) Tubulin PF00091.20 KOS22000.1 - 2.3e-68 230.2 0.0 3.3e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KOS22000.1 - 1e-46 158.0 0.1 1.7e-46 157.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KOS22000.1 - 0.00035 20.0 0.0 0.00075 19.0 0.0 1.6 2 0 0 2 2 2 1 Tubulin domain DUF1415 PF07209.7 KOS22000.1 - 0.047 13.4 0.1 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) Brix PF04427.13 KOS22001.1 - 3.6e-47 160.4 0.2 4.5e-47 160.1 0.1 1.1 1 0 0 1 1 1 1 Brix domain Peptidase_M14 PF00246.19 KOS22002.1 - 9e-36 123.9 0.0 1.3e-35 123.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase ATG22 PF11700.3 KOS22003.1 - 6e-195 648.2 15.3 6.9e-195 648.0 10.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KOS22003.1 - 0.00079 18.2 20.4 0.00079 18.2 14.2 3.6 2 1 1 3 3 3 2 Major Facilitator Superfamily UPF1_Zn_bind PF09416.5 KOS22004.1 - 7.4e-71 236.6 3.6 9.2e-71 236.3 1.0 2.3 3 0 0 3 3 3 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KOS22004.1 - 1.6e-60 203.9 0.0 5.4e-60 202.2 0.0 1.9 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 KOS22004.1 - 4e-56 190.2 1.4 6.1e-56 189.6 0.9 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS22004.1 - 4.1e-14 52.0 0.2 1.1e-13 50.7 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KOS22004.1 - 5.3e-13 48.9 0.2 2.5e-11 43.5 0.2 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KOS22004.1 - 1.8e-08 34.4 0.0 3.7e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KOS22004.1 - 5e-05 22.9 0.2 0.13 11.7 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KOS22004.1 - 0.00091 18.7 0.2 0.002 17.6 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_RecD PF05127.9 KOS22004.1 - 0.0011 18.6 0.1 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.4 KOS22004.1 - 0.0015 17.5 0.6 0.009 15.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Ribosomal_S13_N PF08069.7 KOS22004.1 - 0.0028 17.4 0.0 0.0068 16.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain KaiC PF06745.8 KOS22004.1 - 0.0042 16.2 0.0 0.03 13.4 0.0 2.0 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.1 KOS22004.1 - 0.0043 16.4 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 KOS22004.1 - 0.0056 16.0 0.0 0.1 11.9 0.0 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 KOS22004.1 - 0.013 14.5 0.5 1.8 7.4 0.0 2.3 1 1 0 2 2 2 0 PIF1-like helicase AAA_10 PF12846.2 KOS22004.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.17 KOS22004.1 - 0.18 11.2 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF2763 PF10961.3 KOS22006.1 - 0.001 19.4 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2763) Fer4 PF00037.22 KOS22007.1 - 1.6e-13 49.6 16.5 5.5e-08 32.0 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KOS22007.1 - 7.6e-12 45.4 10.6 1.2e-11 44.7 7.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KOS22007.1 - 7.7e-10 38.8 8.6 1.4e-09 38.0 5.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 KOS22007.1 - 1.4e-09 38.5 7.3 0.00023 21.8 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 KOS22007.1 - 2.4e-09 36.8 22.0 7.5e-08 32.0 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 KOS22007.1 - 1.1e-08 34.7 32.3 1.2e-05 25.0 8.7 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.1 KOS22007.1 - 1.2e-07 31.6 20.4 2.3e-05 24.3 8.0 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KOS22007.1 - 1.4e-07 30.9 14.7 0.00045 19.9 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KOS22007.1 - 2.7e-07 30.1 17.1 0.0013 18.5 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 KOS22007.1 - 5.6e-06 26.2 12.7 0.0006 19.9 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 KOS22007.1 - 9.6e-06 25.8 10.1 0.00091 19.5 7.7 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 KOS22007.1 - 6.4e-05 23.3 9.8 0.017 15.5 0.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 KOS22007.1 - 0.0092 16.3 15.1 0.31 11.4 3.2 2.6 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 KOS22007.1 - 0.016 15.7 13.1 0.22 12.0 1.1 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 KOS22007.1 - 0.076 13.6 16.9 0.16 12.5 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 KOS22007.1 - 0.13 12.4 4.8 0.28 11.3 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain F_actin_cap_B PF01115.12 KOS22009.1 - 4.5e-108 360.0 0.0 5.2e-108 359.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit BAH PF01426.13 KOS22010.1 - 2.6e-05 23.9 0.0 4.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 BAH domain FbpA PF05833.6 KOS22011.1 - 1.4e-35 122.7 7.5 1.4e-35 122.7 5.2 2.2 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 KOS22011.1 - 3e-35 120.2 0.1 3e-35 120.2 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 KOS22011.1 - 2e-18 66.0 0.0 5.2e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Prenyltransf PF01255.14 KOS22012.1 - 8.7e-10 38.1 0.0 5.1e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Sec10 PF07393.6 KOS22013.1 - 2.4e-217 723.5 6.8 2.8e-217 723.2 4.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 MRP-S31 PF15433.1 KOS22013.1 - 0.014 14.8 0.1 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 KfrA_N PF11740.3 KOS22013.1 - 0.66 10.4 5.0 9.8 6.6 0.0 3.4 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term Dus PF01207.12 KOS22014.1 - 5.1e-07 28.8 0.0 0.0022 16.8 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Dus PF01207.12 KOS22015.1 - 1.2e-25 90.0 0.0 1.6e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Cas_csx3 PF09620.5 KOS22016.1 - 0.095 12.5 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) FAA_hydrolase PF01557.13 KOS22017.1 - 5.5e-62 209.0 0.0 7.1e-62 208.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.10 KOS22018.1 - 1.3e-16 60.1 3.8 1.5e-16 59.9 2.7 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KOS22018.1 - 4.4e-13 49.2 3.8 5e-13 49.0 2.6 1.1 1 0 0 1 1 1 1 Complex1_LYR-like dDENN PF03455.14 KOS22018.1 - 0.00025 21.0 0.3 0.00033 20.6 0.2 1.1 1 0 0 1 1 1 1 dDENN domain PSI PF01437.20 KOS22019.1 - 0.039 14.1 13.6 0.063 13.4 9.4 1.4 1 0 0 1 1 1 0 Plexin repeat ThiS PF02597.15 KOS22020.1 - 1.2e-08 35.2 0.0 1.7e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 ThiS family Smg4_UPF3 PF03467.10 KOS22021.1 - 8.1e-27 94.3 0.0 3.7e-26 92.1 0.0 2.1 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.17 KOS22021.1 - 6.5e-08 32.0 0.3 2e-06 27.3 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS22021.1 - 2e-07 30.8 0.0 2.2e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS22021.1 - 9.6e-05 22.1 0.0 0.00027 20.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KOS22021.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Metallophos PF00149.23 KOS22022.1 - 1.1e-37 129.4 0.2 1.8e-32 112.3 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Met_10 PF02475.11 KOS22023.1 - 1.8e-05 24.4 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KOS22023.1 - 0.00017 21.5 1.0 0.0013 18.7 0.7 2.2 1 1 0 1 1 1 1 Methyltransferase domain EF-hand_6 PF13405.1 KOS22024.1 - 3.2e-08 32.7 0.3 0.0028 17.4 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KOS22024.1 - 5.3e-05 23.2 0.7 9.5e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KOS22024.1 - 0.00036 19.7 0.0 0.0021 17.3 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.27 KOS22024.1 - 0.00079 18.5 0.2 0.015 14.5 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KOS22024.1 - 0.016 14.7 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair PepSY_2 PF13670.1 KOS22024.1 - 0.28 11.1 0.1 0.28 11.1 0.1 1.9 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain DUF972 PF06156.8 KOS22026.1 - 0.00045 20.5 3.3 0.0029 17.9 0.2 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF972) Leu_zip PF15294.1 KOS22026.1 - 0.001 18.2 0.5 0.12 11.5 0.1 2.3 2 0 0 2 2 2 1 Leucine zipper PLRV_ORF5 PF01690.12 KOS22026.1 - 0.0033 16.6 0.3 0.0042 16.3 0.2 1.2 1 0 0 1 1 1 1 Potato leaf roll virus readthrough protein Herpes_BLRF2 PF05812.7 KOS22026.1 - 0.0077 16.0 1.1 0.15 11.8 0.0 2.5 1 1 1 2 2 2 1 Herpesvirus BLRF2 protein SNAPc19 PF15497.1 KOS22026.1 - 0.0078 16.4 1.0 1.6 8.9 0.7 2.7 3 0 0 3 3 3 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 ADIP PF11559.3 KOS22026.1 - 0.0094 15.8 2.4 0.0094 15.8 1.7 2.3 2 1 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 KOS22026.1 - 0.023 15.0 1.8 0.023 15.0 1.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 KOS22026.1 - 0.11 12.0 3.7 0.26 10.8 1.4 2.0 2 0 0 2 2 2 0 IncA protein CCDC155 PF14662.1 KOS22026.1 - 0.12 11.9 9.7 1.3 8.5 3.5 2.4 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 TSC22 PF01166.13 KOS22026.1 - 0.15 12.0 4.7 3.1 7.8 1.8 2.9 3 0 0 3 3 3 0 TSC-22/dip/bun family DivIC PF04977.10 KOS22026.1 - 0.46 10.0 11.4 0.32 10.5 3.6 3.3 2 2 1 3 3 3 0 Septum formation initiator V_ATPase_I PF01496.14 KOS22026.1 - 0.7 7.6 2.6 2 6.1 1.7 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 KOS22026.1 - 0.95 9.3 15.2 0.24 11.2 6.0 2.9 3 0 0 3 3 2 0 Basic region leucine zipper Jnk-SapK_ap_N PF09744.4 KOS22026.1 - 1.6 8.7 7.7 0.12 12.3 0.8 2.3 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 APG6 PF04111.7 KOS22026.1 - 1.6 7.6 5.1 0.71 8.8 1.6 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 KOS22026.1 - 1.9 7.3 6.6 4.7 6.0 4.2 2.0 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 KOS22026.1 - 2.8 7.9 12.7 0.62 10.0 3.0 3.0 4 0 0 4 4 2 0 bZIP transcription factor DivIVA PF05103.8 KOS22026.1 - 3.4 7.7 7.6 0.83 9.7 1.2 2.6 3 0 0 3 3 3 0 DivIVA protein Cep57_CLD_2 PF14197.1 KOS22026.1 - 6.2 6.8 19.8 0.26 11.2 0.8 4.6 4 1 1 5 5 5 0 Centrosome localisation domain of PPC89 IncA PF04156.9 KOS22027.1 - 0.00012 21.6 3.8 0.00012 21.6 2.6 2.3 1 1 0 2 2 2 1 IncA protein APG6 PF04111.7 KOS22027.1 - 0.00052 19.1 8.6 0.00052 19.1 6.0 2.1 1 1 1 2 2 2 1 Autophagy protein Apg6 Reo_sigmaC PF04582.7 KOS22027.1 - 0.0051 16.0 5.2 0.0074 15.5 3.6 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein ERM PF00769.14 KOS22027.1 - 0.0075 15.8 9.5 0.0075 15.8 6.6 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family DUF3584 PF12128.3 KOS22027.1 - 0.3 8.3 30.3 0.46 7.7 21.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3810 PF12725.2 KOS22027.1 - 0.48 9.2 3.1 0.54 9.1 1.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) BLOC1_2 PF10046.4 KOS22027.1 - 0.97 9.6 10.1 0.26 11.4 1.0 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Gag_spuma PF03276.9 KOS22027.1 - 1.6 6.9 19.3 2.3 6.4 13.3 1.2 1 0 0 1 1 1 0 Spumavirus gag protein U79_P34 PF03064.11 KOS22027.1 - 4.1 6.8 33.3 2.8 7.3 21.7 1.7 1 1 1 2 2 2 0 HSV U79 / HCMV P34 CotJB PF12652.2 KOS22027.1 - 8.3 6.5 6.6 3.7 7.7 0.1 3.0 3 1 0 3 3 3 0 CotJB protein TRF PF08558.5 KOS22029.1 - 7.8e-18 64.6 0.0 5.1e-12 45.6 0.2 2.2 1 1 1 2 2 2 2 Telomere repeat binding factor (TRF) HNOBA PF07701.9 KOS22029.1 - 0.01 15.0 0.3 0.01 15.0 0.2 1.7 2 0 0 2 2 2 0 Heme NO binding associated FRG1 PF06229.7 KOS22029.1 - 0.2 11.0 5.6 0.48 9.8 3.9 1.6 1 0 0 1 1 1 0 FRG1-like family Spore_coat_CotO PF14153.1 KOS22029.1 - 1.3 8.3 15.4 0.058 12.8 5.9 1.9 2 0 0 2 2 2 0 Spore coat protein CotO Peptidase_S30 PF01577.11 KOS22030.1 - 0.017 14.5 2.5 0.021 14.2 1.7 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease Calici_MSP PF05752.6 KOS22030.1 - 0.045 13.3 0.1 0.086 12.4 0.0 1.4 1 1 0 1 1 1 0 Calicivirus minor structural protein CPSF100_C PF13299.1 KOS22030.1 - 0.051 13.7 4.3 0.062 13.4 3.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DNA_pol_viral_N PF00242.12 KOS22030.1 - 0.078 11.9 8.2 0.085 11.8 5.7 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 KOS22030.1 - 0.24 9.6 13.0 0.28 9.4 9.0 1.0 1 0 0 1 1 1 0 Transmembrane protein SSP160 PF06933.6 KOS22030.1 - 0.37 8.7 11.1 0.4 8.5 7.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF2215 PF10225.4 KOS22030.1 - 0.86 8.9 5.4 1 8.7 3.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Ndc1_Nup PF09531.5 KOS22030.1 - 3 6.1 7.1 3.1 6.1 4.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup P30 PF07390.6 KOS22030.1 - 5.4 6.4 9.5 8.2 5.8 6.6 1.3 1 0 0 1 1 1 0 Mycoplasma P30 protein Presenilin PF01080.12 KOS22030.1 - 8.2 5.1 6.6 8.2 5.1 4.5 1.1 1 0 0 1 1 1 0 Presenilin Maf1 PF09174.5 KOS22030.1 - 8.8 6.1 10.8 12 5.6 7.5 1.2 1 0 0 1 1 1 0 Maf1 regulator Choline_transpo PF04515.7 KOS22031.1 - 1.6e-105 352.5 18.2 1.6e-105 352.5 12.6 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter zf-C2H2_2 PF12756.2 KOS22032.1 - 2.3e-34 117.5 13.7 1.1e-28 99.2 3.7 3.6 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KOS22032.1 - 3.4e-07 30.2 1.3 3.4e-07 30.2 0.9 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KOS22032.1 - 4.2e-07 29.9 8.2 8.3e-07 28.9 1.9 4.4 4 1 1 5 5 5 2 Zinc-finger double-stranded RNA-binding DUF629 PF04780.7 KOS22032.1 - 0.0015 17.1 0.0 0.003 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.1 KOS22032.1 - 0.011 15.5 5.6 0.81 9.6 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger DUF4504 PF14953.1 KOS22032.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) SerH PF06873.6 KOS22032.1 - 5.6 5.4 11.7 3.4 6.1 0.8 2.3 2 1 0 2 2 2 0 Cell surface immobilisation antigen SerH Acetyltransf_1 PF00583.19 KOS22034.1 - 1.4e-06 28.2 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS22034.1 - 0.00014 21.9 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS22034.1 - 0.001 19.1 0.1 0.0018 18.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS22034.1 - 0.032 14.0 0.1 0.053 13.3 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KOS22034.1 - 0.15 11.7 0.1 0.31 10.8 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein AftA_N PF12250.3 KOS22035.1 - 0.086 11.5 0.0 0.093 11.4 0.0 1.0 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal Methyltransf_31 PF13847.1 KOS22036.1 - 1.4e-16 60.4 0.0 1.9e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS22036.1 - 9.9e-13 48.6 0.0 2e-12 47.6 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS22036.1 - 3.4e-10 40.2 0.0 7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS22036.1 - 7.5e-10 39.0 0.1 2.2e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS22036.1 - 1.7e-08 34.3 0.0 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS22036.1 - 4.4e-08 33.5 0.0 7.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS22036.1 - 2.7e-07 30.6 0.5 1.6e-06 28.1 0.3 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KOS22036.1 - 3.1e-07 29.9 0.0 4.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KOS22036.1 - 4e-07 29.2 0.0 5.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 KOS22036.1 - 1.2e-05 24.5 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 KOS22036.1 - 0.0041 16.6 0.0 0.0057 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 KOS22036.1 - 0.0052 15.9 0.0 0.0085 15.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.8 KOS22036.1 - 0.025 13.7 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 KOS22036.1 - 0.036 13.0 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF4349 PF14257.1 KOS22036.1 - 0.1 11.7 0.1 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) MMR_HSR1 PF01926.18 KOS22037.1 - 2.9e-16 59.4 0.0 4e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KOS22037.1 - 0.00026 20.8 0.1 0.0068 16.2 0.3 2.3 2 1 0 2 2 2 1 Dynamin family Miro PF08477.8 KOS22037.1 - 0.0021 18.5 0.0 0.017 15.6 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KOS22037.1 - 0.0024 17.1 0.0 0.087 12.0 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KOS22037.1 - 0.0044 16.2 0.0 0.014 14.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KOS22037.1 - 0.0096 15.4 0.0 0.027 13.9 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family GTP_EFTU PF00009.22 KOS22037.1 - 0.011 15.1 0.0 0.19 11.1 0.0 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KOS22037.1 - 0.018 14.5 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AIG1 PF04548.11 KOS22037.1 - 0.028 13.5 0.0 0.21 10.6 0.0 2.0 1 1 0 1 1 1 0 AIG1 family Septin PF00735.13 KOS22037.1 - 0.059 12.3 0.0 0.16 10.9 0.0 1.7 1 1 0 1 1 1 0 Septin AAA_25 PF13481.1 KOS22037.1 - 0.13 11.6 0.1 10 5.4 0.0 2.5 1 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KOS22037.1 - 0.19 11.4 0.0 0.49 10.0 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase HECT PF00632.20 KOS22038.1 - 3.9e-72 243.0 0.0 4.9e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) 2OG-FeII_Oxy_2 PF13532.1 KOS22039.1 - 3.5e-33 115.0 0.0 6.7e-33 114.1 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KOS22039.1 - 0.037 14.5 0.3 0.15 12.5 0.0 2.2 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily CDC45 PF02724.9 KOS22039.1 - 0.11 10.5 1.4 0.14 10.1 1.0 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 KOS22039.1 - 0.42 10.9 7.3 0.75 10.1 5.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal adh_short PF00106.20 KOS22040.1 - 2.6e-18 66.4 0.2 4.8e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS22040.1 - 1.4e-15 57.7 0.1 1.8e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KOS22040.1 - 0.032 13.3 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) AAA_29 PF13555.1 KOS22041.1 - 0.0072 15.8 0.1 0.022 14.2 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KOS22041.1 - 0.016 16.0 0.1 0.072 13.9 0.0 2.3 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 KOS22041.1 - 0.022 14.4 0.3 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 KOS22041.1 - 0.036 14.3 0.0 0.088 13.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 KOS22041.1 - 0.044 13.9 0.0 0.2 11.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KOS22041.1 - 0.048 13.9 0.3 0.32 11.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 KOS22041.1 - 0.075 12.2 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 KOS22041.1 - 0.082 13.2 0.0 0.61 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KOS22041.1 - 0.1 12.1 0.1 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KOS22041.1 - 0.16 11.3 2.7 5.6 6.2 0.3 3.0 2 1 0 2 2 2 0 AAA-like domain Augurin PF15187.1 KOS22041.1 - 0.88 9.4 4.2 1.4 8.7 0.1 2.9 3 0 0 3 3 3 0 Oesophageal cancer-related gene 4 COQ7 PF03232.8 KOS22043.1 - 3.6e-64 215.3 0.1 4.2e-64 215.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 KOS22043.1 - 0.0012 19.1 0.1 0.0022 18.3 0.0 1.6 1 1 0 1 1 1 1 Rubrerythrin PLDc PF00614.17 KOS22044.1 - 1e-16 60.1 1.1 8.1e-08 31.8 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KOS22044.1 - 1.2e-11 44.4 0.1 3.7e-07 29.9 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 KOS22044.1 - 1.3e-07 31.4 0.0 9.9e-07 28.5 0.0 2.5 2 1 0 2 2 2 1 PX domain GDPD PF03009.12 KOS22045.1 - 4.3e-25 88.6 0.0 6.2e-19 68.4 0.0 2.6 1 1 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KOS22045.1 - 1.8 8.8 4.3 4.1 7.7 0.0 2.9 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family Plus-3 PF03126.13 KOS22046.1 - 2.5e-26 91.8 0.0 8.2e-26 90.1 0.0 1.9 2 0 0 2 2 2 1 Plus-3 domain RsbRD_N PF14361.1 KOS22046.1 - 0.42 11.0 7.9 2.5 8.6 0.3 2.8 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Diphthamide_syn PF01866.12 KOS22047.1 - 2.6e-46 158.2 0.0 1.5e-45 155.8 0.0 1.9 1 1 0 1 1 1 1 Putative diphthamide synthesis protein MutS_V PF00488.16 KOS22048.1 - 5.7e-80 268.1 0.1 9.2e-80 267.4 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KOS22048.1 - 9.4e-48 162.7 0.0 2e-47 161.6 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KOS22048.1 - 5.1e-33 113.4 0.1 1.1e-32 112.3 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 KOS22048.1 - 2.4e-14 53.2 0.2 9.4e-14 51.3 0.1 2.1 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 KOS22048.1 - 1.9e-13 50.6 0.0 9.5e-13 48.3 0.0 2.3 1 1 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 KOS22048.1 - 0.0045 17.3 0.1 0.0045 17.3 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KOS22048.1 - 0.011 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KOS22048.1 - 0.069 13.1 0.2 0.069 13.1 0.2 2.2 2 0 0 2 2 2 0 AAA domain MARVEL PF01284.18 KOS22049.1 - 9.6e-15 54.6 20.1 1.1e-14 54.4 13.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain MARVEL PF01284.18 KOS22050.1 - 0.023 14.5 8.3 0.033 14.0 5.7 1.2 1 0 0 1 1 1 0 Membrane-associating domain MASE2 PF05230.6 KOS22050.1 - 0.05 13.5 4.0 0.91 9.5 0.0 2.2 2 0 0 2 2 2 0 MASE2 domain DUF1469 PF07332.6 KOS22050.1 - 0.17 11.6 3.9 0.087 12.5 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Hepatitis_core PF00906.15 KOS22050.1 - 0.24 11.0 1.9 0.38 10.3 1.3 1.2 1 0 0 1 1 1 0 Hepatitis core antigen DUF4293 PF14126.1 KOS22050.1 - 0.67 9.8 3.8 1.2 9.0 2.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF1129 PF06570.6 KOS22050.1 - 6.3 6.0 5.6 2.1 7.5 1.7 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Bud13 PF09736.4 KOS22051.1 - 0.8 9.9 6.9 0.06 13.6 1.4 1.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex UbiA PF01040.13 KOS22052.1 - 3.6e-31 108.3 20.2 3.6e-31 108.3 14.0 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family Pex14_N PF04695.8 KOS22052.1 - 4 7.5 11.4 4 7.4 6.9 1.9 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dabb PF07876.7 KOS22053.1 - 1.2e-11 44.9 0.0 1.4e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Acyl_transf_1 PF00698.16 KOS22054.1 - 1.9e-57 194.9 0.0 3.6e-57 194.1 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KOS22054.1 - 1.4e-52 177.9 0.2 4.3e-52 176.3 0.1 1.9 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.21 KOS22054.1 - 2.5e-46 158.2 0.6 7.6e-46 156.6 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 KOS22054.1 - 2.6e-45 154.8 0.0 5e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KOS22054.1 - 7.8e-42 143.0 0.4 1.9e-41 141.7 0.3 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KOS22054.1 - 1.9e-35 121.3 0.3 9.9e-35 118.9 0.1 2.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KOS22054.1 - 1.2e-10 41.0 0.1 4.9e-10 39.0 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 KOS22054.1 - 1.5e-06 27.8 0.0 4.3e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.18 KOS22054.1 - 0.002 17.1 0.2 0.0048 15.9 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 KOS22054.1 - 0.0048 17.1 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 KOS22054.1 - 0.017 14.8 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF915 PF06028.6 KOS22054.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) MFS_1 PF07690.11 KOS22055.1 - 2.5e-10 39.5 26.9 1.2e-08 34.0 18.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KOS22055.1 - 3.5e-08 32.1 12.3 4e-08 31.9 8.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1761 PF08570.5 KOS22055.1 - 0.016 15.2 1.3 0.016 15.2 0.9 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1761) DUF1772 PF08592.6 KOS22055.1 - 0.39 10.4 8.0 4.5 7.0 0.4 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) MatE PF01554.13 KOS22055.1 - 0.69 9.5 13.7 2.6 7.6 2.4 2.8 1 1 0 2 2 2 0 MatE Annexin PF00191.15 KOS22056.1 - 6.4e-18 64.4 1.3 0.00013 21.7 0.0 4.4 4 0 0 4 4 4 4 Annexin Methyltransf_23 PF13489.1 KOS22057.1 - 5.7e-05 22.8 0.0 8.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS22057.1 - 7.5e-05 23.2 0.0 0.00057 20.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 KOS22057.1 - 0.043 13.4 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KOS22057.1 - 0.062 12.8 0.0 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.10 KOS22057.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G FtsJ PF01728.14 KOS22057.1 - 0.077 12.9 0.1 0.41 10.6 0.0 2.1 2 1 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 KOS22057.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain eIF-5a PF01287.15 KOS22058.1 - 0.00015 21.6 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF2207 PF09972.4 KOS22059.1 - 8.4 4.8 15.2 9.3 4.7 10.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_C1_2 PF03051.10 KOS22060.1 - 1.9e-146 488.0 0.0 2.2e-146 487.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KOS22060.1 - 2.4e-06 27.6 0.2 0.095 12.5 0.2 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Ala_racemase_N PF01168.15 KOS22063.1 - 1.4e-41 142.4 0.1 1.6e-41 142.2 0.1 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.15 KOS22064.1 - 2.8e-120 402.1 12.9 3.3e-120 401.8 9.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KOS22064.1 - 4.5e-45 152.2 0.0 1.8e-44 150.3 0.0 2.1 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KOS22064.1 - 3.3e-21 75.7 0.0 7.1e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Xpo1 PF08389.7 KOS22064.1 - 0.09 12.6 2.8 1.4 8.8 0.1 3.0 3 0 0 3 3 3 0 Exportin 1-like protein Methyltransf_11 PF08241.7 KOS22065.1 - 5.1e-09 36.5 0.0 1.1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS22065.1 - 8.4e-09 35.3 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS22065.1 - 3.1e-07 30.7 0.0 5.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS22065.1 - 6.5e-06 25.7 0.0 2e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS22065.1 - 0.0024 18.2 0.0 0.0046 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS22065.1 - 0.019 15.5 0.1 0.18 12.4 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 KOS22065.1 - 0.048 12.7 0.0 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PHO4 PF01384.15 KOS22066.1 - 2.1e-79 266.5 14.8 2.6e-79 266.2 10.2 1.1 1 0 0 1 1 1 1 Phosphate transporter family P16-Arc PF04699.9 KOS22066.1 - 4.5e-32 111.1 0.0 7e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) peroxidase PF00141.18 KOS22067.1 - 9.3e-83 277.2 0.0 6.6e-50 169.7 0.0 2.3 2 0 0 2 2 2 2 Peroxidase PLDc_2 PF13091.1 KOS22070.1 - 2.2e-17 62.9 0.0 5.6e-11 42.2 0.0 3.1 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KOS22070.1 - 0.00022 20.9 0.1 0.029 14.1 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif SRPRB PF09439.5 KOS22071.1 - 9.2e-27 93.4 0.0 1.5e-25 89.4 0.0 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KOS22071.1 - 4e-07 29.9 0.0 6.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KOS22071.1 - 2.6e-06 26.8 0.0 0.0003 20.0 0.0 2.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KOS22071.1 - 8.8e-05 22.0 0.0 0.0011 18.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.13 KOS22071.1 - 0.014 14.3 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Septin Ras PF00071.17 KOS22071.1 - 0.015 14.7 0.0 0.052 12.9 0.0 1.9 2 0 0 2 2 2 0 Ras family Miro PF08477.8 KOS22071.1 - 0.027 14.9 0.0 0.2 12.1 0.0 2.2 1 1 0 1 1 1 0 Miro-like protein MCM PF00493.18 KOS22071.1 - 0.042 12.6 0.1 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family AAA_16 PF13191.1 KOS22071.1 - 0.051 13.5 0.6 0.25 11.2 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain Gtr1_RagA PF04670.7 KOS22071.1 - 0.084 11.9 0.0 0.16 11.1 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 KOS22071.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase PALP PF00291.20 KOS22072.1 - 2.9e-60 204.1 0.1 4.2e-60 203.5 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KOS22072.1 - 3.1e-10 39.6 0.0 7.1e-09 35.3 0.0 2.5 2 0 0 2 2 2 1 CBS domain HSF_DNA-bind PF00447.12 KOS22073.1 - 3.5e-29 101.0 0.1 2.5e-28 98.2 0.0 2.3 2 0 0 2 2 2 1 HSF-type DNA-binding Ets PF00178.17 KOS22073.1 - 0.042 13.9 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Ets-domain Pro_isomerase PF00160.16 KOS22074.1 - 4.4e-43 147.1 0.0 8.7e-43 146.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.1 KOS22074.1 - 0.06 13.5 0.2 0.06 13.5 0.1 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4604) Pro_isomerase PF00160.16 KOS22075.1 - 2.4e-46 157.7 0.0 2.7e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF829 PF05705.9 KOS22077.1 - 3.6e-38 131.6 0.0 4.4e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) MFS_1 PF07690.11 KOS22078.1 - 1.7e-39 135.5 29.7 1.7e-39 135.5 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.18 KOS22079.1 - 6.3e-10 38.6 0.0 1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Peptidase_M20 PF01546.23 KOS22080.1 - 9.7e-28 96.9 0.5 1.7e-27 96.1 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KOS22080.1 - 3e-05 23.7 0.0 8.3e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KOS22080.1 - 0.00011 21.9 0.1 0.00033 20.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 tRNA_int_end_N2 PF12928.2 KOS22081.1 - 2.6e-16 58.8 0.0 4.7e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KOS22081.1 - 0.0072 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain LysM PF01476.15 KOS22083.1 - 2.8e-10 39.8 0.0 4.1e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 LysM domain HEAT_EZ PF13513.1 KOS22084.1 - 2.8e-22 78.5 8.8 3e-07 30.7 0.2 9.5 9 3 2 11 11 10 4 HEAT-like repeat HEAT PF02985.17 KOS22084.1 - 5.7e-22 75.7 6.5 0.00049 19.9 0.1 8.5 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.1 KOS22084.1 - 3.3e-16 59.3 16.5 0.0011 19.1 0.3 7.8 4 2 4 8 8 7 6 HEAT repeats Vac14_Fab1_bd PF12755.2 KOS22084.1 - 2.8e-07 30.8 0.0 0.11 12.8 0.0 5.3 4 1 4 8 8 6 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 KOS22084.1 - 5.5e-07 29.4 0.5 2.3e-06 27.4 0.1 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 KOS22084.1 - 1.3e-06 27.0 0.1 0.067 11.5 0.0 4.0 3 2 1 4 4 4 2 Adaptin N terminal region RIX1 PF08167.7 KOS22084.1 - 5.1e-06 26.2 0.0 0.079 12.6 0.0 3.8 3 1 0 3 3 3 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 KOS22084.1 - 0.00023 20.5 0.0 0.3 10.4 0.0 3.7 3 0 0 3 3 3 1 CLASP N terminal UME PF08064.8 KOS22084.1 - 0.0005 19.9 0.0 0.53 10.2 0.0 4.4 4 0 0 4 4 4 1 UME (NUC010) domain MMS19_N PF14500.1 KOS22084.1 - 0.00053 19.3 0.1 0.77 8.9 0.0 3.6 3 1 2 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II Cohesin_HEAT PF12765.2 KOS22084.1 - 0.0036 17.2 0.1 0.49 10.3 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 KOS22084.1 - 0.046 13.5 2.4 3.2 7.5 0.0 4.5 6 2 0 6 6 5 0 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 KOS22084.1 - 0.091 11.4 2.8 6 5.4 0.0 3.4 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal DUF2435 PF10363.4 KOS22084.1 - 0.13 12.1 2.1 2.4 8.1 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) Arm PF00514.18 KOS22084.1 - 0.23 11.3 11.9 2 8.3 0.0 7.2 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat Asparaginase_2 PF01112.13 KOS22085.1 - 2.4e-39 134.9 5.2 1.1e-19 70.2 0.1 4.8 5 0 0 5 5 5 3 Asparaginase Sporozoite_P67 PF05642.6 KOS22085.1 - 5.9 4.6 5.6 8.5 4.0 3.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tim17 PF02466.14 KOS22086.1 - 4.9e-33 113.9 5.9 6e-33 113.6 4.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DLH PF01738.13 KOS22088.1 - 1.4e-21 76.7 0.0 1.8e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KOS22088.1 - 0.00023 20.9 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS22088.1 - 0.075 12.8 0.0 0.26 11.1 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF3628 PF12300.3 KOS22089.1 - 0.47 10.4 7.5 0.84 9.6 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) DUF2613 PF11021.3 KOS22089.1 - 7.1 6.4 7.0 11 5.8 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF747 PF05346.6 KOS22090.1 - 5.8e-129 429.8 6.9 6.6e-129 429.7 4.8 1.0 1 0 0 1 1 1 1 Eukaryotic membrane protein family OAD_gamma PF04277.8 KOS22090.1 - 0.12 12.7 1.1 0.28 11.5 0.8 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PIR PF00399.14 KOS22091.1 - 1.1e-07 30.8 3.4 3.3e-07 29.3 2.4 1.8 1 0 0 1 1 1 1 Yeast PIR protein repeat Gpi16 PF04113.9 KOS22092.1 - 1.3e-226 753.0 0.0 1.6e-226 752.7 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component PMT PF02366.13 KOS22093.1 - 7e-81 271.1 13.8 7e-81 271.1 9.6 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KOS22093.1 - 1.4e-38 132.3 0.7 1.9e-38 131.8 0.5 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.3 KOS22093.1 - 0.15 11.5 3.1 1.2 8.6 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Ras PF00071.17 KOS22094.1 - 4.9e-48 162.5 0.0 6.7e-37 126.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KOS22094.1 - 3e-16 59.9 0.0 1.9e-15 57.3 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS22094.1 - 3e-08 33.1 0.0 2.1e-07 30.3 0.0 2.2 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KOS22094.1 - 2.8e-05 23.6 0.0 0.00032 20.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KOS22094.1 - 0.00024 21.0 0.0 0.00054 19.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KOS22094.1 - 0.00044 19.4 0.0 0.00065 18.8 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KOS22094.1 - 0.018 15.1 0.0 0.6 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KOS22094.1 - 0.11 12.4 0.6 0.31 10.9 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 KOS22094.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Choline_transpo PF04515.7 KOS22095.1 - 1.6e-15 56.7 20.2 2.2e-13 49.6 13.2 3.2 3 0 0 3 3 3 2 Plasma-membrane choline transporter WD40 PF00400.27 KOS22096.1 - 4.1e-10 39.1 8.7 0.056 13.3 0.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 KOS22096.1 - 0.0082 14.3 0.1 0.18 9.9 0.1 2.4 3 0 0 3 3 3 2 Nucleoporin Nup120/160 AMP-binding PF00501.23 KOS22097.1 - 2.5e-78 263.3 0.0 3e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF3301 PF11743.3 KOS22097.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Cys_Met_Meta_PP PF01053.15 KOS22098.1 - 7.7e-150 498.4 0.0 8.8e-150 498.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KOS22098.1 - 2e-11 43.5 0.4 6.7e-11 41.8 0.1 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KOS22098.1 - 6.3e-10 38.5 0.0 1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KOS22098.1 - 4.2e-08 32.3 0.5 5.9e-08 31.8 0.1 1.4 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KOS22098.1 - 1.9e-07 30.5 0.0 3.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 KOS22098.1 - 0.0014 16.9 0.1 0.0018 16.6 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 KOS22098.1 - 0.022 13.2 0.0 0.043 12.2 0.0 1.5 2 0 0 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GDC-P PF02347.11 KOS22098.1 - 0.033 12.8 0.0 0.048 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein PKD_channel PF08016.7 KOS22099.1 - 0.029 12.7 8.4 0.49 8.7 1.3 2.2 2 0 0 2 2 2 0 Polycystin cation channel DUF2012 PF09430.5 KOS22100.1 - 2.3e-22 79.1 0.0 3e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) WW PF00397.21 KOS22101.1 - 1.6e-05 24.6 1.3 3.5e-05 23.5 0.9 1.6 1 0 0 1 1 1 1 WW domain Mito_carr PF00153.22 KOS22102.1 - 9.2e-28 95.8 6.1 6.7e-12 44.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MBD PF01429.14 KOS22102.1 - 0.0018 17.7 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyl-CpG binding domain Pex14_N PF04695.8 KOS22103.1 - 0.028 14.4 4.4 0.5 10.4 2.3 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SIT PF15330.1 KOS22103.1 - 1.4 9.0 8.5 13 5.9 2.6 2.6 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT FHIPEP PF00771.15 KOS22103.1 - 1.9 6.7 5.6 3.3 5.9 3.8 1.3 1 0 0 1 1 1 0 FHIPEP family DUF4557 PF15101.1 KOS22103.1 - 3 7.6 11.3 6 6.6 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF1980 PF09323.5 KOS22103.1 - 3.3 7.4 4.9 46 3.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Serinc PF03348.10 KOS22103.1 - 3.6 6.1 4.7 0.72 8.5 0.6 1.7 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF4185 PF13810.1 KOS22104.1 - 3.2e-09 36.1 3.2 3.2e-09 36.1 2.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4185) DASH_Dad3 PF08656.5 KOS22105.1 - 1.1e-27 95.5 0.1 1.2e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 HalX PF08663.5 KOS22105.1 - 0.085 12.8 0.2 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 HalX domain YopE PF03545.8 KOS22105.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) Ribosomal_S5_C PF03719.10 KOS22106.1 - 6.1e-19 67.0 0.0 2e-17 62.2 0.0 3.0 3 0 0 3 3 3 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KOS22106.1 - 3.3e-09 36.3 0.2 8e-09 35.1 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Adaptin_N PF01602.15 KOS22107.1 - 3.5e-95 319.3 2.0 6e-95 318.5 1.4 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 KOS22107.1 - 1e-62 209.6 0.0 2.9e-62 208.1 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 KOS22107.1 - 5.6e-62 207.5 0.1 1.1e-61 206.5 0.1 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 KOS22107.1 - 1.7e-10 41.0 11.5 3.7e-07 30.3 0.0 4.8 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.2 KOS22107.1 - 9e-06 25.6 3.5 0.00088 19.1 0.0 3.2 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KOS22107.1 - 0.0024 17.8 0.7 3 8.1 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 KOS22107.1 - 0.023 15.1 2.9 9.4 6.8 0.0 4.5 3 1 1 4 4 4 0 HEAT-like repeat Peptidase_M20 PF01546.23 KOS22108.1 - 2.2e-21 76.2 0.0 3.8e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KOS22108.1 - 3.3e-14 52.1 7.5 0.00014 21.6 0.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat M20_dimer PF07687.9 KOS22108.1 - 2.5e-05 24.0 0.0 4.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Nucleoporin_N PF08801.6 KOS22108.1 - 0.12 11.1 0.1 0.41 9.3 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like WD40 PF00400.27 KOS22110.1 - 3.3e-53 175.7 14.4 1.2e-08 34.5 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KOS22110.1 - 5.9e-11 41.9 0.8 1.3e-10 40.8 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS22110.1 - 1e-10 40.9 0.2 3e-10 39.4 0.2 1.9 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KOS22110.1 - 0.00093 17.4 7.8 2.9 5.9 0.1 5.1 2 2 4 6 6 6 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KOS22110.1 - 0.0075 15.7 0.7 1.4 8.2 0.0 3.1 2 1 0 2 2 2 1 PQQ-like domain PRANC PF09372.5 KOS22110.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 PRANC domain CPSF_A PF03178.10 KOS22110.1 - 0.21 10.6 0.2 0.72 8.8 0.0 1.9 3 0 0 3 3 3 0 CPSF A subunit region DUF4328 PF14219.1 KOS22111.1 - 0.013 14.8 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) FPN1 PF06963.7 KOS22111.1 - 0.018 13.4 0.0 0.019 13.3 0.0 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF4149 PF13664.1 KOS22111.1 - 0.046 13.7 0.3 0.054 13.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) CAP_N PF01213.14 KOS22111.1 - 0.27 10.5 2.1 0.33 10.1 1.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PSP1 PF04468.7 KOS22112.1 - 6.1e-30 103.0 0.8 1.4e-29 101.8 0.6 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Na_H_Exchanger PF00999.16 KOS22113.1 - 1.4e-38 132.4 14.9 1.9e-38 132.0 10.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family RNase_H PF00075.19 KOS22114.1 - 3.3e-28 98.6 1.4 7e-28 97.6 0.0 2.1 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.11 KOS22114.1 - 4.7e-28 96.9 7.4 2.2e-14 53.1 0.5 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin BAF1_ABF1 PF04684.8 KOS22114.1 - 0.0014 17.5 20.7 0.0025 16.7 14.3 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 KOS22114.1 - 0.0085 15.1 2.9 0.011 14.7 2.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter G0-G1_switch_2 PF15103.1 KOS22114.1 - 0.34 11.1 4.3 0.74 10.0 3.0 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 CDC45 PF02724.9 KOS22114.1 - 0.58 8.1 6.1 0.78 7.6 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SelP_N PF04592.9 KOS22114.1 - 0.7 9.2 11.9 1 8.6 8.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Tom37_C PF11801.3 KOS22114.1 - 3.2 7.6 5.8 5.5 6.8 4.0 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain CDC45 PF02724.9 KOS22115.1 - 0.02 12.9 5.3 0.024 12.6 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 KOS22115.1 - 0.028 13.5 7.8 0.044 12.8 5.4 1.3 1 0 0 1 1 1 0 BUD22 DUF1981 PF09324.5 KOS22115.1 - 0.25 10.8 0.9 0.45 10.0 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) FAM176 PF14851.1 KOS22115.1 - 1.1 8.9 4.2 2.2 7.9 2.9 1.6 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.8 KOS22115.1 - 2.9 7.4 9.2 5.3 6.6 6.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.7 KOS22115.1 - 3.3 7.3 13.8 0.53 9.9 6.8 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 KOS22115.1 - 6.9 4.4 12.6 11 3.8 8.7 1.2 1 0 0 1 1 1 0 Nop14-like family Ank PF00023.25 KOS22116.1 - 8.2e-15 53.7 0.7 4e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KOS22116.1 - 1.1e-12 48.0 0.1 2.2e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KOS22116.1 - 9.4e-11 41.9 0.2 3.8e-10 40.0 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TIG PF01833.19 KOS22116.1 - 2.7e-10 40.1 0.5 6.5e-10 38.8 0.3 1.7 1 0 0 1 1 1 1 IPT/TIG domain Ank_5 PF13857.1 KOS22116.1 - 1.1e-09 38.1 0.1 7.6e-09 35.5 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS22116.1 - 9e-06 25.4 0.2 0.18 12.1 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Daxx PF03344.10 KOS22116.1 - 0.0083 14.6 26.1 0.023 13.2 18.1 1.7 1 0 0 1 1 1 1 Daxx Family RR_TM4-6 PF06459.7 KOS22116.1 - 0.21 11.4 18.6 0.52 10.1 12.9 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Merozoite_SPAM PF07133.6 KOS22116.1 - 0.46 10.3 30.4 0.92 9.3 21.1 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Ycf1 PF05758.7 KOS22116.1 - 0.53 7.9 8.4 0.8 7.3 5.8 1.1 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 KOS22116.1 - 0.59 10.1 13.1 1.2 9.1 9.1 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Spore_coat_CotO PF14153.1 KOS22116.1 - 0.65 9.4 14.6 1.6 8.1 10.1 1.6 1 0 0 1 1 1 0 Spore coat protein CotO Hid1 PF12722.2 KOS22116.1 - 1.2 6.7 6.5 1.9 6.0 4.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.7 KOS22116.1 - 1.3 6.8 34.0 2 6.2 23.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KOS22116.1 - 1.5 6.7 19.7 2.4 6.0 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.9 KOS22116.1 - 1.9 7.9 13.7 5.6 6.4 9.5 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FHIPEP PF00771.15 KOS22116.1 - 3.1 5.9 3.4 4.9 5.3 2.4 1.2 1 0 0 1 1 1 0 FHIPEP family SpoIIP PF07454.6 KOS22116.1 - 3.8 6.5 12.5 12 5.0 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SDA1 PF05285.7 KOS22116.1 - 5.1 6.2 29.6 9.7 5.3 20.5 1.3 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 KOS22116.1 - 6.5 6.0 24.3 12 5.1 16.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 KOS22116.1 - 8.9 6.0 9.7 26 4.4 6.7 1.8 1 0 0 1 1 1 0 DDHD domain Arm PF00514.18 KOS22117.1 - 5.3e-09 35.5 14.9 8.2e-05 22.2 0.4 7.4 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KOS22117.1 - 0.0025 17.7 17.0 0.83 9.9 0.1 7.6 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 KOS22117.1 - 0.0048 17.3 14.0 0.16 12.4 0.0 6.7 5 1 2 7 7 7 1 HEAT-like repeat V-ATPase_H_C PF11698.3 KOS22117.1 - 0.052 13.4 0.4 1.6 8.6 0.0 2.7 1 1 1 2 2 2 0 V-ATPase subunit H Proteasom_PSMB PF10508.4 KOS22117.1 - 7.3 4.7 6.4 2.1 6.5 0.4 2.5 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit RHIM PF12721.2 KOS22117.1 - 9.8 6.6 8.4 4.2 7.8 3.5 2.2 2 0 0 2 2 2 0 RIP homotypic interaction motif Velvet PF11754.3 KOS22118.1 - 7e-64 215.1 0.0 1e-63 214.6 0.0 1.2 1 0 0 1 1 1 1 Velvet factor ASFV_J13L PF05568.6 KOS22118.1 - 0.6 9.6 4.9 1 8.8 3.0 1.6 2 0 0 2 2 2 0 African swine fever virus J13L protein Ribosomal_60s PF00428.14 KOS22118.1 - 6.3 7.2 8.8 13 6.2 6.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2360 PF10152.4 KOS22119.1 - 1.4 9.2 4.2 2.1 8.6 2.9 1.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Cyclin PF08613.6 KOS22120.1 - 1.3e-28 100.3 0.1 2e-28 99.7 0.1 1.4 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KOS22120.1 - 0.00015 21.3 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain SNARE PF05739.14 KOS22121.1 - 3.9e-09 36.0 1.2 5.6e-09 35.5 0.9 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 KOS22121.1 - 0.0069 15.8 0.0 0.0084 15.5 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Peptidase_G2 PF11962.3 KOS22121.1 - 0.024 13.7 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase_G2, IMC autoproteolytic cleavage domain CHZ PF09649.5 KOS22122.1 - 2.7e-14 52.0 0.1 2.7e-14 52.0 0.1 3.5 5 0 0 5 5 5 1 Histone chaperone domain CHZ BUD22 PF09073.5 KOS22122.1 - 4 6.4 21.8 4.4 6.2 15.1 1.0 1 0 0 1 1 1 0 BUD22 SGT1 PF07093.6 KOS22122.1 - 8.1 4.6 16.2 8.9 4.5 11.2 1.0 1 0 0 1 1 1 0 SGT1 protein PAP2 PF01569.16 KOS22123.1 - 5.9e-17 61.5 6.3 1.1e-16 60.6 3.8 1.9 1 1 0 1 1 1 1 PAP2 superfamily Rep_fac_C PF08542.6 KOS22124.1 - 1.1e-14 54.1 0.0 2.3e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 KOS22124.1 - 4.9e-14 52.6 0.0 2.1e-13 50.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KOS22124.1 - 7.3e-12 45.2 0.0 6e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.10 KOS22124.1 - 4.7e-09 35.4 0.0 7.4e-07 28.2 0.0 2.4 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KOS22124.1 - 1e-06 28.4 0.0 5.1e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 KOS22124.1 - 2e-06 27.9 0.2 5.4e-05 23.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KOS22124.1 - 7.5e-06 26.0 0.1 0.00028 20.9 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 KOS22124.1 - 1.4e-05 24.7 0.0 3.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KOS22124.1 - 2.2e-05 24.1 0.1 0.00012 21.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KOS22124.1 - 3.8e-05 22.8 0.0 9.9e-05 21.4 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KOS22124.1 - 4.1e-05 23.3 0.2 0.00036 20.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KOS22124.1 - 6.6e-05 21.7 0.1 0.28 9.8 0.0 2.5 3 0 0 3 3 3 2 TIP49 C-terminus DUF815 PF05673.8 KOS22124.1 - 7e-05 21.8 0.0 0.00013 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.8 KOS22124.1 - 0.00032 20.2 0.0 0.00057 19.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KOS22124.1 - 0.00058 19.7 0.0 0.0033 17.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 KOS22124.1 - 0.0012 18.4 0.1 0.0034 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 KOS22124.1 - 0.0021 17.3 0.0 0.22 10.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 KOS22124.1 - 0.0051 15.9 0.2 0.026 13.7 0.1 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KOS22124.1 - 0.0081 15.7 0.0 0.044 13.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KOS22124.1 - 0.0094 15.9 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KOS22124.1 - 0.011 15.1 0.0 0.035 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KOS22124.1 - 0.03 15.1 0.0 0.085 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 KOS22124.1 - 0.031 13.7 0.0 0.51 9.8 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.1 KOS22124.1 - 0.05 13.8 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 KOS22124.1 - 0.053 12.9 0.2 2.3 7.5 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 KOS22124.1 - 0.06 12.8 0.0 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.10 KOS22124.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 KOS22124.1 - 0.077 12.3 0.0 0.39 10.1 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KOS22124.1 - 0.086 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 KOS22124.1 - 0.089 12.4 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 KOS22124.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) BTB_2 PF02214.17 KOS22125.1 - 1.1e-05 25.4 0.0 0.00032 20.8 0.0 2.5 2 0 0 2 2 2 1 BTB/POZ domain DUF1664 PF07889.7 KOS22126.1 - 3.9 7.2 6.2 1.8 8.3 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4559 PF15112.1 KOS22126.1 - 7.6 5.6 14.9 1.7 7.7 5.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) BRE1 PF08647.6 KOS22126.1 - 9.7 6.2 27.2 2.2 8.2 9.5 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Cyt-b5 PF00173.23 KOS22127.1 - 2e-09 37.1 0.0 3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cu_bind_like PF02298.12 KOS22128.1 - 0.00072 19.2 0.2 0.002 17.8 0.1 1.8 1 1 0 1 1 1 1 Plastocyanin-like domain CENP-X PF09415.5 KOS22129.1 - 1.8e-24 85.3 0.1 2.7e-24 84.7 0.1 1.3 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CDC45 PF02724.9 KOS22129.1 - 0.41 8.6 5.8 0.41 8.6 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 KOS22129.1 - 0.71 8.2 6.6 0.78 8.1 4.6 1.1 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 KOS22129.1 - 2.9 7.4 7.0 3.4 7.2 4.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Mito_carr PF00153.22 KOS22130.1 - 3.9e-66 218.8 3.9 2.4e-23 81.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S25 PF03297.10 KOS22131.1 - 1.5e-37 127.8 5.6 1.6e-37 127.7 3.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 KOS22131.1 - 0.033 13.5 0.1 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.15 KOS22131.1 - 0.05 13.7 0.0 0.077 13.1 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator Ribosomal_S7 PF00177.16 KOS22132.1 - 6.8e-40 136.0 1.5 8.5e-40 135.7 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Melibiase PF02065.13 KOS22133.1 - 3e-05 22.9 0.0 5.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.21 KOS22133.1 - 0.0022 16.9 0.0 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_97 PF10566.4 KOS22133.1 - 0.055 12.5 0.0 0.38 9.8 0.0 2.0 1 1 0 1 1 1 0 Glycoside hydrolase 97 Augurin PF15187.1 KOS22133.1 - 0.098 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Oesophageal cancer-related gene 4 Glyco_transf_28 PF03033.15 KOS22134.1 - 5.9e-20 71.4 0.0 1.3e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.11 KOS22134.1 - 1.3e-05 24.9 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.13 KOS22134.1 - 1.6e-05 23.6 0.0 2.3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Methyltransf_PK PF05891.7 KOS22135.1 - 3.5e-59 199.7 0.0 4e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.13 KOS22135.1 - 0.0027 16.9 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 KOS22135.1 - 0.019 15.4 0.0 0.032 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain B_lectin PF01453.19 KOS22136.1 - 4.8e-27 94.1 1.0 2.1e-13 50.1 0.1 2.0 1 1 1 2 2 2 2 D-mannose binding lectin PQQ PF01011.16 KOS22136.1 - 0.013 14.9 1.1 1.7 8.3 0.1 3.0 2 1 1 3 3 3 0 PQQ enzyme repeat PQQ_2 PF13360.1 KOS22136.1 - 0.067 12.6 0.4 0.27 10.6 0.3 1.9 1 1 0 1 1 1 0 PQQ-like domain RNase_HII PF01351.13 KOS22137.1 - 7e-46 156.3 0.0 4.5e-44 150.4 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease HII RHD3 PF05879.7 KOS22138.1 - 0 1018.2 0.0 0 1018.0 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KOS22138.1 - 2.4e-08 33.3 0.1 4.3e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KOS22138.1 - 1.6e-06 28.0 0.1 3.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KOS22138.1 - 0.00012 21.9 0.0 0.00037 20.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KOS22138.1 - 0.00058 20.3 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 KOS22138.1 - 0.0017 18.3 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 KOS22138.1 - 0.024 13.6 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 Septin DUF3693 PF12472.3 KOS22138.1 - 0.065 12.8 0.0 0.25 10.9 0.0 1.9 1 0 0 1 1 1 0 Phage related protein DUF3006 PF11213.3 KOS22138.1 - 0.12 12.1 2.3 0.19 11.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) RNA12 PF10443.4 KOS22139.1 - 1e-148 495.4 0.0 1.5e-148 494.8 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 KOS22139.1 - 4.3e-09 36.4 0.0 3.3e-08 33.5 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 KOS22139.1 - 3.3e-05 23.4 0.0 9.2e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.1 KOS22139.1 - 0.00021 21.3 0.1 0.0011 19.0 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain RRM_5 PF13893.1 KOS22139.1 - 0.00053 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 KOS22139.1 - 0.0031 17.3 0.2 0.0077 16.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) RRM_6 PF14259.1 KOS22139.1 - 0.016 15.1 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AAA_14 PF13173.1 KOS22139.1 - 0.16 11.8 0.0 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain CENP-C_C PF11699.3 KOS22140.1 - 3.7e-33 113.3 0.1 5.7e-33 112.7 0.1 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 KOS22140.1 - 2.6e-08 33.2 0.1 3.6e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 KOS22140.1 - 0.0027 17.0 0.3 0.026 13.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 KOS22140.1 - 0.03 13.7 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 Cupin Cupin_6 PF12852.2 KOS22140.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.14 KOS22140.1 - 0.12 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain HSP70 PF00012.15 KOS22141.1 - 2.3e-269 894.4 5.2 2.7e-269 894.2 3.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KOS22141.1 - 1.1e-17 63.6 0.0 3e-16 58.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KOS22141.1 - 0.0041 16.7 0.0 0.0087 15.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KOS22141.1 - 0.015 14.4 0.0 0.038 13.0 0.0 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KOS22141.1 - 0.03 14.1 1.7 2.2 8.1 0.3 3.0 2 2 0 2 2 2 0 Cell division protein FtsA StbA PF06406.6 KOS22141.1 - 0.052 12.4 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 StbA protein PMBR PF09373.5 KOS22141.1 - 0.13 12.2 0.8 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 Pseudomurein-binding repeat DUF1843 PF08898.5 KOS22141.1 - 1.2 9.2 3.9 1.2 9.2 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF3128 PF11326.3 KOS22142.1 - 3.3e-22 78.4 0.9 4.6e-22 77.9 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Peptidase_C2 PF00648.16 KOS22143.1 - 3e-53 180.7 1.2 4.6e-37 127.6 0.4 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease AA_permease PF00324.16 KOS22144.1 - 1.4e-134 449.0 47.6 1.7e-134 448.7 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KOS22144.1 - 9.6e-37 126.5 54.2 1.3e-36 126.1 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.19 KOS22145.1 - 5e-07 29.6 0.9 2.6e-06 27.3 0.6 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS22145.1 - 0.00026 21.0 0.0 0.001 19.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS22145.1 - 0.0017 18.2 0.0 0.059 13.2 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS22145.1 - 0.0024 17.9 0.0 0.0053 16.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NicO PF03824.11 KOS22146.1 - 6.3e-61 206.1 12.2 6.3e-61 206.1 8.5 1.4 2 0 0 2 2 2 1 High-affinity nickel-transport protein Ldh_2 PF02615.9 KOS22147.1 - 1.1e-99 333.4 0.1 1.2e-99 333.2 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase SET PF00856.23 KOS22148.1 - 1.4e-09 38.4 2.5 8.4e-09 35.9 0.0 3.0 2 1 0 2 2 2 1 SET domain Trypan_PARP PF05887.6 KOS22148.1 - 2.1 8.1 29.9 2.7 7.8 19.4 2.1 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Peptidase_M28 PF04389.12 KOS22149.1 - 3.8e-33 114.7 0.0 6.5e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KOS22149.1 - 1.8e-16 59.6 0.3 4.5e-16 58.3 0.1 1.8 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 KOS22149.1 - 0.003 17.0 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KOS22149.1 - 0.0097 14.7 0.0 0.061 12.0 0.0 2.0 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase DUF3583 PF12126.3 KOS22149.1 - 0.05 12.6 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Ribosomal_L30 PF00327.15 KOS22150.1 - 1.1e-16 60.1 0.0 1.4e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e CoA_binding PF02629.14 KOS22151.1 - 7.2e-19 68.1 0.0 2e-18 66.6 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Citrate_synt PF00285.16 KOS22151.1 - 1.1e-17 63.7 0.0 1.4e-14 53.6 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 KOS22151.1 - 1.5e-15 57.1 0.0 2.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KOS22151.1 - 6.2e-06 25.8 0.0 0.00023 20.8 0.0 2.5 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CEP1-DNA_bind PF09287.5 KOS22151.1 - 0.099 12.0 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 CEP-1, DNA binding CENP-Q PF13094.1 KOS22152.1 - 3.7e-27 95.3 0.1 6.3e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF2411 PF10304.4 KOS22154.1 - 6e-12 44.7 0.1 1.1e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) Tudor-knot PF11717.3 KOS22156.1 - 8.4e-08 31.8 0.8 2.4e-07 30.3 0.2 1.8 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain MRG PF05712.8 KOS22157.1 - 5.3e-46 155.9 0.0 1.1e-45 155.0 0.0 1.4 1 1 0 1 1 1 1 MRG NAD_binding_4 PF07993.7 KOS22158.1 - 6.5e-66 221.7 0.0 9.8e-66 221.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KOS22158.1 - 3.3e-64 216.8 0.0 1.9e-63 214.3 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Cnl2_NKP2 PF09447.5 KOS22158.1 - 1.6e-19 69.2 0.0 3.8e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Cnl2/NKP2 family protein Epimerase PF01370.16 KOS22158.1 - 3.3e-12 46.3 0.0 8.2e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KOS22158.1 - 1.5e-08 34.7 0.0 3.3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KOS22158.1 - 2.4e-08 34.8 0.0 1.1e-07 32.7 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KOS22158.1 - 7.7e-08 31.3 0.0 2.6e-07 29.6 0.0 1.8 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KOS22158.1 - 0.0029 17.6 0.0 0.086 12.8 0.0 2.7 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KOS22158.1 - 0.022 13.6 0.0 0.13 11.1 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain DUF3842 PF12953.2 KOS22158.1 - 0.098 12.8 0.1 4.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3842) Meth_synt_2 PF01717.13 KOS22159.1 - 1.4e-144 481.0 0.0 1e-137 458.4 0.0 3.3 3 1 1 4 4 4 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KOS22159.1 - 1e-119 399.4 0.0 1.2e-108 363.0 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 KOS22159.1 - 0.015 14.2 0.0 1.1 8.1 0.0 2.7 2 1 0 3 3 3 0 Uroporphyrinogen decarboxylase (URO-D) CCDC155 PF14662.1 KOS22159.1 - 0.073 12.6 1.3 0.15 11.5 0.9 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DIT1_PvcA PF05141.7 KOS22160.1 - 9.9e-86 287.4 0.0 1.3e-85 287.1 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 KOS22160.1 - 1.2e-20 74.2 0.0 2.6e-20 73.1 0.0 1.5 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_3 PF01494.14 KOS22161.1 - 4.9e-37 127.8 0.0 7.4e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DEAD PF00270.24 KOS22162.1 - 5.4e-40 136.6 0.0 1.3e-39 135.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS22162.1 - 3.3e-21 74.9 0.1 1e-20 73.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Nucleoplasmin PF03066.10 KOS22162.1 - 3.5 7.1 21.4 0.038 13.5 3.6 3.4 3 0 0 3 3 3 0 Nucleoplasmin TPR_MLP1_2 PF07926.7 KOS22163.1 - 3.6e-31 107.6 26.4 3.6e-31 107.6 18.3 16.8 7 4 8 15 15 15 4 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KOS22163.1 - 0.0005 19.9 20.3 0.0005 19.9 14.0 17.2 5 4 9 16 16 16 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF904 PF06005.7 KOS22163.1 - 0.0011 19.2 5.7 0.0011 19.2 4.0 23.7 12 8 3 15 15 15 1 Protein of unknown function (DUF904) Striatin PF08232.7 KOS22163.1 - 0.0053 17.0 12.3 0.0053 17.0 8.5 17.7 4 3 11 15 15 15 3 Striatin family Hce2 PF14856.1 KOS22164.1 - 2.3e-09 37.0 0.0 3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Pinin_SDK_memA PF04696.8 KOS22165.1 - 0.01 15.3 2.7 0.019 14.5 1.9 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region SR-25 PF10500.4 KOS22165.1 - 0.019 14.4 3.7 0.019 14.4 2.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2011 PF09428.5 KOS22165.1 - 0.16 11.8 4.3 0.35 10.7 2.3 1.9 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) MSA-2c PF12238.3 KOS22165.1 - 0.48 10.0 2.5 1.4 8.5 0.8 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c Polyoma_coat2 PF00761.15 KOS22165.1 - 1.4 8.3 6.2 1.1 8.6 1.1 2.1 2 0 0 2 2 2 0 Polyomavirus coat protein Hira PF07569.6 KOS22166.1 - 2.5e-81 272.0 0.0 6.1e-81 270.8 0.0 1.7 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 KOS22166.1 - 7.1e-43 143.0 20.8 3.4e-07 29.8 0.1 9.0 8 0 0 8 8 8 8 WD domain, G-beta repeat HIRA_B PF09453.5 KOS22166.1 - 5.1e-08 32.2 0.4 5.1e-08 32.2 0.3 2.0 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.7 KOS22166.1 - 0.001 18.6 0.8 36 4.1 0.0 4.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 KOS22166.1 - 0.085 10.6 0.0 0.33 8.7 0.0 1.8 2 0 0 2 2 2 0 IKI3 family CsgE PF10627.4 KOS22166.1 - 0.19 11.5 0.0 0.46 10.3 0.0 1.6 1 0 0 1 1 1 0 Curli assembly protein CsgE Herpes_LMP2 PF07415.6 KOS22166.1 - 2.5 6.6 4.9 15 4.0 2.0 2.1 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein Herpes_LMP1 PF05297.6 KOS22166.1 - 3 6.6 9.0 5.3 5.8 6.2 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Macoilin PF09726.4 KOS22166.1 - 6.4 4.9 5.4 13 3.9 3.8 1.4 1 0 0 1 1 1 0 Transmembrane protein Glyco_transf_15 PF01793.11 KOS22169.1 - 7.5e-49 166.4 0.1 1.9e-48 165.1 0.1 1.6 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CcmD PF04995.9 KOS22169.1 - 0.042 13.5 2.2 0.11 12.2 1.5 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Adeno_IVa2 PF02456.10 KOS22169.1 - 0.24 10.0 0.0 0.34 9.5 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein Helicase_C_2 PF13307.1 KOS22170.1 - 2.4e-38 131.7 0.0 2.8e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain Transp_cyt_pur PF02133.10 KOS22171.1 - 0.068 11.7 0.0 0.077 11.5 0.0 1.1 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin NIF PF03031.13 KOS22172.1 - 1.9e-27 95.8 0.0 4.2e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KOS22172.1 - 3.7e-09 36.2 0.3 1.1e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 KOS22172.1 - 2.2e-08 34.1 0.0 5.6e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ribosomal_S2 PF00318.15 KOS22172.1 - 0.0089 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S2 Biotin_lipoyl PF00364.17 KOS22172.1 - 0.04 13.5 0.0 5.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Biotin-requiring enzyme Cnd1_N PF12922.2 KOS22173.1 - 3e-55 186.4 0.4 1.5e-54 184.1 0.0 2.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 KOS22173.1 - 3.8e-55 186.4 1.8 4.8e-52 176.3 0.4 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KOS22173.1 - 1.5e-10 41.2 6.1 7e-06 26.2 0.0 5.8 5 2 1 6 6 6 2 HEAT repeats HEAT PF02985.17 KOS22173.1 - 1.1e-07 31.2 10.0 0.036 14.1 0.0 5.8 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 KOS22173.1 - 2.6e-06 27.7 6.1 0.0062 17.0 0.1 5.4 5 0 0 5 5 5 1 HEAT-like repeat Ald_Xan_dh_C2 PF02738.13 KOS22173.1 - 0.01 14.1 0.0 0.016 13.5 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase DUF2435 PF10363.4 KOS22173.1 - 0.02 14.7 0.0 2.2 8.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Cnd3 PF12719.2 KOS22173.1 - 0.028 13.4 4.7 0.071 12.0 1.0 3.3 3 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Pkinase PF00069.20 KOS22174.1 - 1.3e-40 139.1 0.0 1.3e-36 126.1 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KOS22174.1 - 1.6e-14 53.5 0.0 5.2e-09 35.5 0.0 3.6 2 2 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KOS22174.1 - 0.00049 19.8 0.3 0.0072 16.0 0.0 2.6 3 1 1 4 4 4 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KOS22174.1 - 0.0053 15.7 0.0 0.28 10.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Actino_peptide PF14408.1 KOS22174.1 - 0.14 12.1 0.0 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes Ribosomal_L18e PF00828.14 KOS22175.1 - 3.1e-33 114.9 0.1 3.7e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 WD40 PF00400.27 KOS22176.1 - 3.7e-11 42.4 2.9 0.00034 20.3 0.0 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 KOS22176.1 - 0.076 11.1 0.0 0.1 10.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Glyco_transf_28 PF03033.15 KOS22177.1 - 8.1e-24 83.9 0.0 1.5e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 KOS22177.1 - 6.8e-20 70.3 0.2 3.1e-15 55.4 0.0 2.5 2 0 0 2 2 2 2 GRAM domain PH PF00169.24 KOS22177.1 - 5.4e-11 42.6 0.0 1.3e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 PH domain UDPGT PF00201.13 KOS22177.1 - 6.1e-06 25.0 0.0 9.8e-06 24.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.1 KOS22177.1 - 8.3e-05 22.5 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KOS22177.1 - 0.00013 22.1 0.3 0.0011 19.2 0.1 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 KOS22177.1 - 0.021 14.7 0.0 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 PH domain PH_6 PF15406.1 KOS22177.1 - 0.094 12.7 0.3 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain GRIM-19 PF06212.7 KOS22179.1 - 8.8e-24 83.6 0.1 1.3e-23 83.1 0.1 1.2 1 1 0 1 1 1 1 GRIM-19 protein Steroid_dh PF02544.11 KOS22180.1 - 6.2e-26 90.9 1.0 8.9e-26 90.4 0.7 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KOS22180.1 - 0.0043 16.3 2.4 0.0053 16.0 1.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF621 PF04789.10 KOS22180.1 - 0.042 12.8 1.3 0.065 12.2 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF621) TMCO5 PF14992.1 KOS22181.1 - 0.00084 18.5 0.9 0.0011 18.2 0.7 1.0 1 0 0 1 1 1 1 TMCO5 family DUF349 PF03993.7 KOS22181.1 - 0.022 14.8 0.9 0.041 14.0 0.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Feld-I_B PF09252.5 KOS22181.1 - 0.05 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Allergen Fel d I-B chain DUF1409 PF07197.7 KOS22181.1 - 0.21 11.6 2.1 0.44 10.6 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) Ctf8 PF09696.5 KOS22182.1 - 1.3e-29 102.4 0.0 1.6e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Diphthamide_syn PF01866.12 KOS22183.1 - 8.4e-112 373.3 0.0 1.1e-111 373.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Aldose_epim PF01263.15 KOS22183.1 - 1.2e-43 149.3 0.0 1.7e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase ATP-synt_ab PF00006.20 KOS22184.1 - 4.6e-60 202.7 0.0 6.9e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KOS22184.1 - 5.7e-17 62.2 0.3 1e-16 61.3 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KOS22184.1 - 4.4e-13 49.2 0.9 9.8e-13 48.1 0.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KOS22184.1 - 8.2e-05 22.4 0.3 0.00019 21.2 0.2 1.6 1 0 0 1 1 1 1 HAS barrel domain HMGL-like PF00682.14 KOS22185.1 - 2.8e-39 135.1 0.3 1.7e-38 132.6 0.2 1.9 1 1 0 1 1 1 1 HMGL-like Ribosomal_S8e PF01201.17 KOS22186.1 - 6.5e-48 162.2 2.2 7.7e-48 161.9 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 KOS22186.1 - 0.68 10.2 6.2 0.22 11.8 1.8 2.1 2 1 0 2 2 2 0 Small acidic protein family RabGAP-TBC PF00566.13 KOS22187.1 - 2.5e-44 151.2 9.8 8.2e-44 149.6 0.8 3.4 2 1 0 2 2 2 1 Rab-GTPase-TBC domain HALZ PF02183.13 KOS22187.1 - 0.0036 16.9 0.8 0.0036 16.9 0.5 4.2 4 0 0 4 4 4 1 Homeobox associated leucine zipper DUF913 PF06025.7 KOS22188.1 - 5.2e-99 331.5 0.0 5.2e-99 331.5 0.0 4.9 6 0 0 6 6 6 1 Domain of Unknown Function (DUF913) HECT PF00632.20 KOS22188.1 - 3.3e-92 309.0 0.0 5.1e-92 308.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 KOS22188.1 - 1.2e-87 294.3 0.6 1.2e-87 294.3 0.4 4.2 6 0 0 6 6 6 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 KOS22188.1 - 9.5e-31 105.9 9.3 9.5e-31 105.9 6.4 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4414) UBA PF00627.26 KOS22188.1 - 0.00091 19.0 0.1 0.0046 16.7 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain Ribosomal_S6e PF01092.14 KOS22189.1 - 3.6e-61 204.4 0.6 6.7e-61 203.5 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e DUF336 PF03928.9 KOS22190.1 - 3e-18 65.8 0.3 3.9e-18 65.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF336) LAMTOR PF15454.1 KOS22191.1 - 9.7e-14 51.4 0.0 1.4e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Dynamin_N PF00350.18 KOS22192.1 - 8.5e-15 54.9 0.0 4.8e-14 52.5 0.0 2.2 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 KOS22192.1 - 5.2e-05 23.0 1.7 9.2e-05 22.2 0.1 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain ABC_tran PF00005.22 KOS22192.1 - 0.015 15.5 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 KOS22192.1 - 0.035 14.6 0.0 0.077 13.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein RRM_1 PF00076.17 KOS22193.1 - 1e-19 69.8 0.0 9.1e-10 38.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS22193.1 - 2.5e-17 62.4 0.0 1.7e-09 37.3 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS22193.1 - 7.7e-17 61.0 0.0 8.9e-09 35.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NTP_transferase PF00483.18 KOS22194.1 - 1.1e-30 106.7 0.0 1.5e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 KOS22194.1 - 3.6e-10 38.8 8.4 7.7e-06 25.1 0.1 3.6 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KOS22194.1 - 1.4e-06 28.4 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_tranf_2_3 PF13641.1 KOS22194.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KOS22194.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 IspD PF01128.14 KOS22194.1 - 0.16 11.4 0.0 0.59 9.6 0.0 1.8 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Nuc_sug_transp PF04142.10 KOS22195.1 - 3.8e-68 229.2 2.9 7.3e-68 228.2 2.0 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 KOS22195.1 - 1.3e-05 24.9 14.8 2.5e-05 23.9 2.6 2.7 3 0 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 KOS22195.1 - 3.2e-05 22.9 7.6 0.015 14.2 2.3 2.7 2 1 0 2 2 2 2 UAA transporter family EamA PF00892.15 KOS22195.1 - 5.9e-05 23.1 7.4 5.9e-05 23.1 5.1 2.8 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 KOS22195.1 - 0.00065 19.8 17.4 0.00071 19.7 3.1 2.7 2 1 1 3 3 3 2 Multidrug resistance efflux transporter DUF389 PF04087.9 KOS22195.1 - 4.3 7.2 8.5 0.28 11.1 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF389) DUF4131 PF13567.1 KOS22195.1 - 9.7 5.5 10.8 3.9 6.8 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Vma12 PF11712.3 KOS22196.1 - 0.0065 16.1 1.0 0.0082 15.8 0.7 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF677 PF05055.7 KOS22196.1 - 0.013 14.2 0.5 0.011 14.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Tho2 PF11262.3 KOS22196.1 - 0.03 13.3 1.4 0.039 13.0 1.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FlpD PF02662.11 KOS22196.1 - 0.13 11.9 0.4 0.17 11.6 0.3 1.1 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit DUF342 PF03961.8 KOS22196.1 - 0.27 9.6 1.9 0.28 9.5 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) F-box PF00646.28 KOS22197.1 - 0.00075 19.0 3.3 0.0024 17.4 2.3 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KOS22197.1 - 0.0049 16.5 0.8 0.0049 16.5 0.6 1.9 2 0 0 2 2 2 1 F-box-like CysG_dimeriser PF10414.4 KOS22197.1 - 0.012 15.1 4.2 0.68 9.4 0.8 2.6 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region RPEL PF02755.10 KOS22197.1 - 0.017 14.4 0.1 0.077 12.3 0.0 2.1 2 0 0 2 2 2 0 RPEL repeat PEGSRP PF07623.6 KOS22197.1 - 4 6.8 7.1 5.1 6.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) RPA_interact_N PF14766.1 KOS22198.1 - 0.23 10.9 2.6 0.5 9.8 1.8 1.5 1 0 0 1 1 1 0 Replication protein A interacting N-terminal Med7 PF05983.6 KOS22199.1 - 3.3e-49 166.7 0.0 4.3e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 MED7 protein HTH_15 PF12324.3 KOS22201.1 - 3.7 7.2 8.5 18 5.0 0.1 4.1 5 0 0 5 5 5 0 Helix-turn-helix domain of alkylmercury lyase MFS_1 PF07690.11 KOS22202.1 - 1.3e-18 66.9 71.6 1.3e-15 57.0 29.4 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Ycf1 PF05758.7 KOS22205.1 - 0.00078 17.3 3.1 0.00093 17.0 2.2 1.1 1 0 0 1 1 1 1 Ycf1 RR_TM4-6 PF06459.7 KOS22205.1 - 0.0078 16.1 11.0 0.01 15.7 7.6 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Tim54 PF11711.3 KOS22205.1 - 0.0083 14.7 6.6 0.011 14.3 4.6 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Plasmodium_Vir PF05795.6 KOS22205.1 - 0.037 13.2 0.6 0.047 12.9 0.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein LMBR1 PF04791.11 KOS22205.1 - 0.045 12.3 0.1 0.057 11.9 0.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein YjgP_YjgQ PF03739.9 KOS22205.1 - 0.049 12.3 0.3 0.065 11.9 0.2 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family SAPS PF04499.10 KOS22205.1 - 0.062 11.9 4.5 0.08 11.5 3.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sec62 PF03839.11 KOS22205.1 - 0.066 12.6 7.9 0.03 13.7 3.4 1.8 2 0 0 2 2 2 0 Translocation protein Sec62 DDHD PF02862.12 KOS22205.1 - 0.068 12.9 7.0 0.088 12.5 4.8 1.1 1 0 0 1 1 1 0 DDHD domain SID-1_RNA_chan PF13965.1 KOS22205.1 - 0.14 10.2 0.2 0.17 10.0 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Herpes_DNAp_acc PF04929.7 KOS22205.1 - 0.23 10.3 11.3 0.33 9.8 7.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF106 PF01956.11 KOS22205.1 - 0.25 10.8 1.8 0.37 10.3 1.2 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF1510 PF07423.6 KOS22205.1 - 0.25 10.6 15.1 0.33 10.3 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNase_H2-Ydr279 PF09468.5 KOS22205.1 - 0.35 10.0 7.8 0.46 9.6 5.4 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DHHW PF14286.1 KOS22205.1 - 0.65 9.2 7.2 0.89 8.7 5.0 1.1 1 0 0 1 1 1 0 DHHW protein DUF4557 PF15101.1 KOS22205.1 - 0.69 9.7 12.5 0.98 9.2 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Zip PF02535.17 KOS22205.1 - 0.8 8.6 3.1 1.3 7.9 2.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter AUX_IAA PF02309.11 KOS22205.1 - 1.1 9.0 9.7 1.9 8.1 6.7 1.4 1 0 0 1 1 1 0 AUX/IAA family Endostatin PF06482.6 KOS22205.1 - 1.2 8.5 6.1 1.6 8.0 4.3 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF913 PF06025.7 KOS22205.1 - 1.6 7.3 5.4 2.2 6.9 3.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.11 KOS22205.1 - 1.7 8.4 6.7 2.7 7.8 4.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asp-B-Hydro_N PF05279.6 KOS22205.1 - 1.8 8.3 15.4 2.4 7.9 10.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hid1 PF12722.2 KOS22205.1 - 1.9 6.0 8.9 2.3 5.7 6.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spore_coat_CotO PF14153.1 KOS22205.1 - 3.5 7.0 21.4 5.1 6.5 14.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO PIH1 PF08190.7 KOS22205.1 - 3.8 6.8 17.1 5.7 6.2 11.8 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Paf1 PF03985.8 KOS22205.1 - 4.4 5.9 17.1 5.7 5.5 11.8 1.1 1 0 0 1 1 1 0 Paf1 GAGA_bind PF06217.7 KOS22205.1 - 4.4 7.1 12.9 5.9 6.7 9.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 KOS22205.1 - 5.1 5.0 14.5 6.6 4.6 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.3 KOS22205.1 - 5.5 5.6 18.0 7.5 5.1 12.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Serinc PF03348.10 KOS22205.1 - 5.8 5.5 7.0 9 4.8 4.8 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) MIP-T3 PF10243.4 KOS22205.1 - 6.5 5.1 28.7 8.5 4.7 19.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Glyco_transf_15 PF01793.11 KOS22205.1 - 9.7 5.0 11.0 57 2.5 7.7 1.9 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase Pyr_redox_3 PF13738.1 KOS22206.1 - 1.2e-20 74.5 0.1 4.3e-19 69.3 0.3 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KOS22206.1 - 1.7e-10 40.3 0.0 7.3e-08 31.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KOS22206.1 - 6.2e-10 37.8 0.0 3.9e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KOS22206.1 - 1.7e-09 37.8 5.9 1.1e-06 28.6 4.7 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS22206.1 - 4.8e-08 32.9 0.5 4.8e-08 32.9 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KOS22206.1 - 2.9e-06 27.5 8.9 0.0096 16.3 0.7 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KOS22206.1 - 2.3e-05 24.5 0.9 0.047 13.7 0.1 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KOS22206.1 - 3.1e-05 23.0 2.6 3.1e-05 23.0 1.8 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KOS22206.1 - 0.00022 21.4 0.3 0.0065 16.6 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.19 KOS22206.1 - 0.00028 20.1 0.3 0.0074 15.4 0.1 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KOS22206.1 - 0.0023 17.7 8.7 0.0063 16.2 0.3 3.8 3 1 1 4 4 4 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KOS22206.1 - 0.0057 16.3 0.9 0.01 15.4 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Malic_M PF03949.10 KOS22206.1 - 0.12 11.9 0.8 2.1 7.8 0.1 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain HI0933_like PF03486.9 KOS22206.1 - 0.13 10.6 4.3 0.37 9.2 0.5 2.5 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.12 KOS22206.1 - 0.84 8.6 5.1 0.42 9.6 0.4 2.2 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.16 KOS22206.1 - 1.2 8.6 5.1 2.9 7.4 0.3 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 KOS22206.1 - 2.4 7.5 4.3 0.63 9.3 0.5 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ank PF00023.25 KOS22207.1 - 5.7e-37 123.7 0.8 9.1e-08 31.5 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 KOS22207.1 - 5.6e-34 116.3 0.0 8.2e-16 58.1 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) zf-DHHC PF01529.15 KOS22207.1 - 1.6e-32 112.2 7.8 1.6e-32 112.2 5.4 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.1 KOS22207.1 - 3.4e-28 97.0 4.7 1.5e-08 34.5 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS22207.1 - 1e-25 87.1 0.8 7.7e-07 28.7 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 KOS22207.1 - 3.8e-24 84.6 0.5 1.8e-07 31.5 0.2 4.8 2 1 3 5 5 5 5 Ankyrin repeats (many copies) TPR_11 PF13414.1 KOS22208.1 - 0.00088 18.8 1.6 0.42 10.3 0.3 2.4 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.1 KOS22208.1 - 0.098 12.9 0.7 0.8 10.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L27e PF01777.13 KOS22209.1 - 1.6e-36 124.3 4.0 2e-36 123.9 2.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KOS22209.1 - 0.0012 18.4 0.5 0.0036 16.9 0.4 1.9 1 0 0 1 1 1 1 KOW motif ECM11 PF15463.1 KOS22209.1 - 0.24 11.6 1.3 0.25 11.5 0.2 1.5 2 0 0 2 2 2 0 Extracellular mutant protein 11 Ssl1 PF04056.9 KOS22210.1 - 5.4e-75 251.2 0.0 6.9e-75 250.8 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 KOS22210.1 - 4e-13 49.1 10.9 4e-13 49.1 7.6 3.2 2 2 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 KOS22210.1 - 1.5e-10 41.4 0.0 2.3e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KOS22210.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Glyoxalase PF00903.20 KOS22211.1 - 1.2e-20 73.7 0.1 5.1e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KOS22211.1 - 8.2e-13 48.3 0.1 1.4e-06 28.3 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KOS22211.1 - 5.7e-11 42.9 0.1 7.7e-05 23.2 0.2 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 KOS22211.1 - 5.3e-06 26.4 0.0 0.18 11.7 0.0 3.2 3 0 0 3 3 3 3 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KOS22211.1 - 0.0041 17.0 0.1 0.013 15.4 0.1 1.8 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Sugar_tr PF00083.19 KOS22212.1 - 1e-96 324.2 14.8 1.3e-96 323.8 10.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS22212.1 - 1.5e-26 92.9 23.5 1.5e-26 92.9 16.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KOS22212.1 - 1.2e-06 27.1 18.1 0.00068 18.1 4.5 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein DUF791 PF05631.9 KOS22212.1 - 0.0007 18.3 2.0 0.0013 17.5 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 KOS22212.1 - 0.015 15.0 0.1 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 MFS_1 like family MFS_3 PF05977.8 KOS22212.1 - 0.06 11.4 4.9 0.18 9.9 0.5 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Chs3p PF12271.3 KOS22213.1 - 1.7e-87 293.0 9.0 2.5e-84 282.7 5.2 2.0 1 1 1 2 2 2 2 Chitin synthase III catalytic subunit YvrJ PF12841.2 KOS22213.1 - 0.028 13.7 0.0 0.077 12.2 0.0 1.8 1 0 0 1 1 1 0 YvrJ protein family DUF973 PF06157.6 KOS22213.1 - 0.83 8.5 7.2 0.051 12.5 1.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF973) DUF4149 PF13664.1 KOS22213.1 - 3 7.9 13.8 0.33 11.0 1.1 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4149) DUF1218 PF06749.7 KOS22213.1 - 8.4 6.9 8.5 1 9.8 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) Complex1_LYR PF05347.10 KOS22214.1 - 2e-07 30.6 0.2 1.5e-06 27.8 0.2 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KOS22214.1 - 0.0041 17.2 2.1 0.014 15.5 1.6 1.9 1 1 1 2 2 2 1 Complex1_LYR-like TPT PF03151.11 KOS22216.1 - 2.4e-27 95.4 16.9 2.4e-27 95.4 11.7 2.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KOS22216.1 - 0.00064 18.7 26.4 0.0097 14.8 18.3 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KOS22216.1 - 0.0011 19.0 36.2 0.0038 17.2 8.2 2.8 3 0 0 3 3 3 2 EamA-like transporter family NAD_binding_8 PF13450.1 KOS22217.1 - 5.2e-10 39.1 0.1 1.4e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KOS22217.1 - 1.7e-08 34.0 0.0 4e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KOS22217.1 - 0.0001 22.4 0.1 0.00023 21.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KOS22217.1 - 0.0065 15.5 0.1 0.0098 14.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KOS22217.1 - 0.013 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS22217.1 - 0.068 12.9 0.1 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 KOS22217.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KOS22217.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KOS22217.1 - 0.13 10.6 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein RINGv PF12906.2 KOS22218.1 - 6.5e-16 58.1 7.2 1.1e-15 57.3 5.0 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KOS22218.1 - 0.13 12.0 7.4 0.26 11.1 5.1 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 KOS22218.1 - 9.1 5.9 6.3 17 5.0 4.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DMP1 PF07263.6 KOS22219.1 - 1.9 7.1 7.4 1.9 7.0 5.1 1.1 1 0 0 1 1 1 0 Dentin matrix protein 1 (DMP1) ABC_tran PF00005.22 KOS22220.1 - 5.9e-41 139.9 0.0 4.8e-26 91.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KOS22220.1 - 1e-18 67.7 1.9 2.7e-12 46.6 0.2 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KOS22220.1 - 4.8e-16 58.6 0.1 0.00039 19.7 0.0 4.8 5 0 0 5 5 5 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KOS22220.1 - 6e-07 29.7 0.0 0.27 11.1 0.0 4.0 3 1 1 4 4 4 1 AAA domain AAA_29 PF13555.1 KOS22220.1 - 1.3e-06 27.8 0.1 0.008 15.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KOS22220.1 - 1.4e-05 25.5 0.0 0.19 12.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KOS22220.1 - 4e-05 23.2 0.0 0.033 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_16 PF13191.1 KOS22220.1 - 6.4e-05 23.0 8.6 0.005 16.8 0.2 4.0 4 1 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 KOS22220.1 - 0.00013 22.0 0.0 0.12 12.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KOS22220.1 - 0.00014 21.0 0.0 0.15 11.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KOS22220.1 - 0.00022 20.6 0.1 0.35 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KOS22220.1 - 0.00039 19.4 0.3 0.42 9.4 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KOS22220.1 - 0.0006 19.7 0.0 0.042 13.8 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_19 PF13245.1 KOS22220.1 - 0.00072 19.2 1.9 0.73 9.6 0.0 3.7 3 0 0 3 3 2 1 Part of AAA domain Zeta_toxin PF06414.7 KOS22220.1 - 0.0036 16.4 0.0 2 7.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin FtsK_SpoIIIE PF01580.13 KOS22220.1 - 0.0043 16.5 0.0 0.043 13.2 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.1 KOS22220.1 - 0.0062 16.4 0.1 0.59 10.0 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 KOS22220.1 - 0.0086 15.9 0.1 0.93 9.2 0.0 2.3 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.12 KOS22220.1 - 0.013 15.3 0.4 0.03 14.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 NACHT PF05729.7 KOS22220.1 - 0.03 13.9 0.1 9.1 5.9 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA_17 PF13207.1 KOS22220.1 - 0.051 14.3 0.1 0.86 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KOS22220.1 - 0.074 12.7 0.0 0.53 9.9 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase Cyclin_N PF00134.18 KOS22220.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF2075 PF09848.4 KOS22220.1 - 0.12 11.3 0.1 8 5.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Miro PF08477.8 KOS22220.1 - 0.13 12.7 0.0 30 5.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Viral_helicase1 PF01443.13 KOS22220.1 - 0.2 11.1 0.0 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 KOS22220.1 - 0.25 11.6 0.2 2 8.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.11 KOS22220.1 - 0.7 8.9 0.1 2.3 7.2 0.1 1.9 1 0 0 1 1 1 0 AIG1 family NB-ARC PF00931.17 KOS22220.1 - 0.72 8.6 0.0 14 4.3 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain cobW PF02492.14 KOS22220.1 - 0.89 8.9 2.2 3.9 6.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AA_permease PF00324.16 KOS22223.1 - 5.1e-110 368.0 38.8 6.2e-110 367.7 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KOS22223.1 - 3.5e-20 71.9 42.1 4.7e-20 71.5 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 KOS22223.1 - 0.00075 19.2 3.3 0.00075 19.2 2.3 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF1772) Aldedh PF00171.17 KOS22224.1 - 1.6e-150 501.4 0.0 2e-150 501.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PYNP_C PF07831.8 KOS22224.1 - 0.019 14.4 0.0 0.073 12.5 0.0 2.0 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain GMC_oxred_N PF00732.14 KOS22225.1 - 5.1e-52 176.8 0.0 6.6e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KOS22225.1 - 4.3e-40 137.3 0.0 6.9e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KOS22225.1 - 1.5e-05 24.1 0.2 0.0027 16.6 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KOS22225.1 - 5.4e-05 22.2 0.0 7.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KOS22225.1 - 0.00043 19.2 0.0 0.29 9.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KOS22225.1 - 0.00047 20.1 0.2 0.0019 18.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KOS22225.1 - 0.028 13.0 0.0 0.04 12.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 KOS22225.1 - 0.17 11.7 0.0 0.55 10.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ferric_reduct PF01794.14 KOS22226.1 - 1.7e-13 50.7 14.5 1.7e-13 50.7 10.1 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KOS22226.1 - 1.8e-12 47.0 0.0 3.4e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KOS22226.1 - 7.2e-07 29.2 0.0 1.8e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 KOS22226.1 - 0.00015 21.8 2.0 0.00015 21.8 1.4 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4405) RNA_POL_M_15KD PF02150.11 KOS22228.1 - 3.5e-11 42.6 2.2 3.5e-11 42.6 1.6 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 KOS22228.1 - 0.039 13.7 3.3 0.039 13.7 2.3 2.7 3 1 0 3 3 3 0 Double zinc ribbon Nudix_N_2 PF14803.1 KOS22228.1 - 1.2 8.8 12.3 0.41 10.3 0.7 3.1 3 0 0 3 3 3 0 Nudix N-terminal GFA PF04828.9 KOS22228.1 - 1.8 8.5 10.0 0.46 10.4 0.8 2.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2296 PF10058.4 KOS22228.1 - 4.9 6.9 7.9 0.74 9.6 0.2 2.8 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) MFS_1 PF07690.11 KOS22229.1 - 2.1e-36 125.4 43.5 1.3e-34 119.4 29.1 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS22229.1 - 1.4e-14 53.5 17.3 1.4e-14 53.5 12.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KOS22229.1 - 3.7e-11 41.9 20.8 4.8e-11 41.5 14.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HAUS-augmin3 PF14932.1 KOS22230.1 - 0.0013 17.9 5.4 0.0047 16.1 3.7 2.0 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 3 V_ATPase_I PF01496.14 KOS22230.1 - 0.0046 14.8 1.3 0.0059 14.5 0.9 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Atg14 PF10186.4 KOS22230.1 - 0.021 13.7 11.4 0.012 14.6 5.9 2.2 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DDE_Tnp_IS1595 PF12762.2 KOS22230.1 - 0.047 13.5 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 ISXO2-like transposase domain APG6 PF04111.7 KOS22230.1 - 0.71 8.8 5.2 1.4 7.9 3.6 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Syntaxin PF00804.20 KOS22230.1 - 0.93 9.6 9.5 0.28 11.3 3.1 2.7 3 1 1 4 4 4 0 Syntaxin Prefoldin PF02996.12 KOS22230.1 - 1.1 8.9 7.5 0.57 9.8 0.4 3.6 4 0 0 4 4 4 0 Prefoldin subunit p450 PF00067.17 KOS22231.1 - 7.3e-51 173.1 0.0 9.5e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.8 KOS22232.1 - 8.8e-17 61.2 0.0 1.4e-16 60.5 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KOS22232.1 - 0.032 14.1 0.1 0.043 13.6 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 KOS22233.1 - 1.3e-64 218.1 0.1 6.5e-63 212.5 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KOS22233.1 - 9.6e-58 195.9 0.2 1.5e-57 195.3 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KOS22233.1 - 1.2e-53 181.4 0.5 3.9e-53 179.7 0.1 2.1 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KOS22233.1 - 1.7e-43 148.4 0.1 4.4e-43 147.0 0.1 1.8 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 KOS22233.1 - 1.1e-40 139.6 0.1 2.4e-40 138.5 0.1 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KOS22233.1 - 4.8e-40 136.1 0.0 1e-39 135.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KOS22233.1 - 1.1e-17 64.2 0.0 4.1e-17 62.4 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KOS22233.1 - 1.1e-17 63.7 0.0 3.4e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KOS22233.1 - 3.5e-13 49.5 0.0 1e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS22233.1 - 1.7e-10 41.2 0.0 9.1e-09 35.7 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS22233.1 - 1.3e-09 38.5 0.1 1.4e-08 35.2 0.0 2.9 3 0 0 3 3 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KOS22233.1 - 1.6e-09 38.6 0.0 1.3e-08 35.7 0.0 2.7 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KOS22233.1 - 2.5e-08 33.6 0.0 2.1e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 KOS22233.1 - 2.6e-07 30.7 0.0 6.5e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 KOS22233.1 - 4.1e-05 22.7 0.0 7.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 KOS22233.1 - 0.0017 17.7 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 KOS22233.1 - 0.016 15.2 0.0 0.091 12.7 0.0 2.4 1 0 0 1 1 1 0 Methyltransferase domain ACP_syn_III PF08545.5 KOS22233.1 - 0.035 13.7 0.5 0.094 12.3 0.3 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_16 PF10294.4 KOS22233.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Thiolase_N PF00108.18 KOS22233.1 - 0.11 11.4 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF915 PF06028.6 KOS22233.1 - 0.28 10.2 0.0 0.47 9.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Rotamase PF00639.16 KOS22234.1 - 1.2e-21 77.1 0.1 1.8e-21 76.7 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KOS22234.1 - 6.1e-16 58.7 0.0 7.5e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KOS22234.1 - 1.9e-05 25.2 0.0 2.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KOS22234.1 - 0.00069 19.4 0.2 0.0016 18.2 0.0 1.7 2 0 0 2 2 2 1 WW domain Pyridox_ox_2 PF12900.2 KOS22234.1 - 0.013 15.3 0.2 0.033 14.0 0.2 1.6 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase DUF2379 PF09543.5 KOS22234.1 - 0.095 12.6 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) AAA PF00004.24 KOS22235.1 - 0.024 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 KOS22235.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Torsin MukE PF04288.8 KOS22235.1 - 0.068 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 MukE-like family AAA_22 PF13401.1 KOS22235.1 - 0.079 13.1 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain BCS1_N PF08740.6 KOS22236.1 - 3.1e-41 141.0 0.0 4.1e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KOS22236.1 - 9.9e-18 64.6 0.0 1.5e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KOS22236.1 - 1.2e-05 26.1 0.0 2.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KOS22236.1 - 7.1e-05 22.2 0.0 0.00033 20.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS22236.1 - 0.0021 17.9 0.0 0.0049 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS22236.1 - 0.0024 17.8 0.1 0.033 14.1 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KOS22236.1 - 0.0025 17.5 0.0 0.0054 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KOS22236.1 - 0.0026 17.8 0.0 0.011 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KOS22236.1 - 0.0037 16.7 0.0 0.0083 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KOS22236.1 - 0.0078 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KOS22236.1 - 0.0079 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KOS22236.1 - 0.0084 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 KOS22236.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Miro PF08477.8 KOS22236.1 - 0.019 15.4 0.0 0.033 14.7 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein Zeta_toxin PF06414.7 KOS22236.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KOS22236.1 - 0.033 14.4 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KOS22236.1 - 0.047 12.8 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KOS22236.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.7 KOS22236.1 - 0.081 12.5 0.0 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KOS22236.1 - 0.1 12.8 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 KOS22236.1 - 0.22 11.0 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein LrgB PF04172.11 KOS22237.1 - 1.3e-11 44.0 14.0 1e-06 28.0 1.2 2.5 3 0 0 3 3 3 2 LrgB-like family DUF983 PF06170.7 KOS22237.1 - 0.037 14.1 0.5 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Oxysterol_BP PF01237.13 KOS22238.1 - 1.8e-85 286.5 0.0 2.2e-85 286.2 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein F_bP_aldolase PF01116.15 KOS22239.1 - 2.2e-93 312.5 0.0 2.5e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II VCBS PF13517.1 KOS22240.1 - 5.8e-08 32.9 6.4 0.00012 22.3 2.4 4.1 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KOS22240.1 - 0.36 10.5 6.4 0.21 11.3 1.5 2.7 2 0 0 2 2 2 0 FG-GAP repeat Glyco_hydro_31 PF01055.21 KOS22241.1 - 3.5e-91 306.2 1.0 8.9e-91 304.9 0.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KOS22241.1 - 1.6e-07 31.0 0.9 4.5e-07 29.6 0.6 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like CFEM PF05730.6 KOS22242.1 - 1e-11 44.4 6.8 1.5e-11 43.9 4.7 1.2 1 0 0 1 1 1 1 CFEM domain AalphaY_MDB PF04611.7 KOS22242.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region MRF_C1 PF13887.1 KOS22242.1 - 0.13 11.3 0.1 0.22 10.5 0.1 1.3 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Ribosomal_L14 PF00238.14 KOS22243.1 - 4.5e-44 149.0 1.1 5.1e-44 148.9 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e NARP1 PF12569.3 KOS22244.1 - 2.4e-196 653.5 27.9 2.1e-194 647.0 16.1 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 KOS22244.1 - 2.5e-20 72.5 42.2 0.0001 22.5 0.1 8.7 7 2 2 9 9 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 KOS22244.1 - 1.8e-16 60.2 39.8 0.00011 22.8 0.8 9.3 7 1 1 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 KOS22244.1 - 3.8e-16 58.1 30.0 0.00025 21.4 0.0 11.2 8 4 5 13 13 12 6 Tetratricopeptide repeat TPR_2 PF07719.12 KOS22244.1 - 1.1e-15 56.2 26.4 4.2e-05 23.1 0.1 10.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.1 KOS22244.1 - 1.4e-15 56.6 27.5 1.8e-06 27.4 0.2 7.0 6 1 0 7 7 7 4 TPR repeat TPR_12 PF13424.1 KOS22244.1 - 1.5e-12 47.2 30.5 0.0026 17.6 0.1 7.9 7 1 1 8 8 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 KOS22244.1 - 6.2e-12 44.7 8.7 0.087 13.0 0.0 8.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 KOS22244.1 - 1.8e-10 39.9 25.4 4.7e-06 25.9 0.2 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 KOS22244.1 - 3.6e-10 39.5 11.0 0.00014 21.6 0.1 6.3 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 KOS22244.1 - 9.4e-05 22.4 2.5 0.33 11.5 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KOS22244.1 - 0.0014 18.3 0.0 0.0014 18.3 0.0 7.1 9 0 0 9 9 8 1 Tetratricopeptide repeat DUF1028 PF06267.7 KOS22244.1 - 0.032 13.6 0.0 0.1 12.0 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF1028) TPR_7 PF13176.1 KOS22244.1 - 0.038 13.8 21.9 1.9 8.4 0.0 8.1 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_3 PF07720.7 KOS22244.1 - 0.068 12.9 8.5 0.14 11.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Dispanin PF04505.7 KOS22244.1 - 0.22 11.0 0.8 7 6.2 0.0 3.2 3 0 0 3 3 3 0 Interferon-induced transmembrane protein TPR_10 PF13374.1 KOS22244.1 - 1.3 9.0 20.9 4.2 7.4 0.0 6.7 7 0 0 7 7 5 0 Tetratricopeptide repeat Spore_III_AB PF09548.5 KOS22244.1 - 2.8 7.6 7.2 0.26 11.0 0.1 2.7 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Fis1_TPR_C PF14853.1 KOS22244.1 - 6.5 6.7 12.7 7.6 6.5 0.0 5.5 6 0 0 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat Cid2 PF09774.4 KOS22245.1 - 1.3e-23 83.7 0.1 1.5e-23 83.5 0.1 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Mg-por_mtran_C PF07109.6 KOS22245.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium-protoporphyrin IX methyltransferase C-terminus Cir_N PF10197.4 KOS22247.1 - 0.0006 19.7 0.6 0.0006 19.7 0.4 3.4 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.3 KOS22247.1 - 0.4 11.1 5.7 0.44 11.0 1.9 2.5 2 1 0 2 2 2 0 Pre-mRNA splicing factor AAA PF00004.24 KOS22248.1 - 6.8e-51 171.9 0.0 1e-38 132.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS22248.1 - 1.3e-12 47.9 0.1 0.00055 20.0 0.0 4.1 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.8 KOS22248.1 - 7.3e-11 41.4 0.0 1.1e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 KOS22248.1 - 5.3e-10 39.5 0.0 0.00034 20.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 KOS22248.1 - 1.8e-09 37.6 0.0 9e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KOS22248.1 - 5.8e-09 36.8 0.0 0.0053 17.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 KOS22248.1 - 9.6e-08 31.5 0.2 4.2e-06 26.2 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.1 KOS22248.1 - 9.7e-08 32.0 0.0 0.0081 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KOS22248.1 - 1.3e-07 31.4 0.0 0.00065 19.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KOS22248.1 - 4.9e-07 29.3 0.2 0.012 15.3 0.1 2.7 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 KOS22248.1 - 5.5e-07 29.1 0.3 0.039 13.3 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_2 PF07724.9 KOS22248.1 - 1.3e-06 28.3 0.0 0.00047 20.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KOS22248.1 - 3.4e-06 26.2 0.3 0.074 12.0 0.1 2.8 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KOS22248.1 - 3.7e-06 27.2 0.1 0.067 13.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 KOS22248.1 - 4.9e-06 26.6 0.0 0.05 13.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 KOS22248.1 - 6.6e-06 25.8 0.1 0.032 13.8 0.0 3.5 4 0 0 4 4 3 1 NACHT domain Mg_chelatase PF01078.16 KOS22248.1 - 2.2e-05 23.6 0.4 0.016 14.3 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_N PF02359.13 KOS22248.1 - 3.2e-05 23.7 0.0 8.6e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Arch_ATPase PF01637.13 KOS22248.1 - 3.3e-05 23.7 0.5 14 5.3 0.0 4.1 2 2 2 4 4 4 0 Archaeal ATPase AAA_25 PF13481.1 KOS22248.1 - 4.6e-05 22.9 2.0 0.23 10.8 0.1 3.3 2 1 0 3 3 3 2 AAA domain AAA_24 PF13479.1 KOS22248.1 - 0.00013 21.6 0.3 0.082 12.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KOS22248.1 - 0.00013 22.2 0.2 0.66 10.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.21 KOS22248.1 - 0.0002 20.8 0.0 0.41 10.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 KOS22248.1 - 0.00029 20.5 0.0 0.07 12.7 0.0 3.0 3 0 0 3 3 3 1 Bacterial dnaA protein PhoH PF02562.11 KOS22248.1 - 0.00032 20.0 0.0 0.25 10.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein KaiC PF06745.8 KOS22248.1 - 0.00083 18.5 1.9 0.027 13.5 0.1 2.8 3 0 0 3 3 3 1 KaiC NB-ARC PF00931.17 KOS22248.1 - 0.00099 18.0 0.2 0.92 8.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_28 PF13521.1 KOS22248.1 - 0.0011 18.9 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KOS22248.1 - 0.0022 17.0 0.0 0.19 10.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 KOS22248.1 - 0.0025 16.7 0.0 0.4 9.5 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ResIII PF04851.10 KOS22248.1 - 0.003 17.4 0.3 0.44 10.3 0.0 2.6 2 1 1 3 3 2 1 Type III restriction enzyme, res subunit Torsin PF06309.6 KOS22248.1 - 0.0039 17.0 0.0 0.28 11.0 0.0 2.4 2 0 0 2 2 2 1 Torsin Zeta_toxin PF06414.7 KOS22248.1 - 0.0046 16.0 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.1 KOS22248.1 - 0.007 15.8 0.1 0.57 9.7 0.0 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.1 KOS22248.1 - 0.011 15.2 0.0 0.45 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KOS22248.1 - 0.015 14.9 0.0 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 KOS22248.1 - 0.021 14.8 0.0 9 6.3 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain DNA_pol3_delta2 PF13177.1 KOS22248.1 - 0.025 14.2 0.1 1.4 8.5 0.0 3.2 4 0 0 4 4 3 0 DNA polymerase III, delta subunit AAA_3 PF07726.6 KOS22248.1 - 0.025 14.1 0.0 0.56 9.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KOS22248.1 - 0.038 14.3 0.1 8.6 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 KOS22248.1 - 0.064 12.7 0.3 15 5.0 0.0 3.4 2 2 0 3 3 3 0 DEAD/DEAH box helicase AAA_10 PF12846.2 KOS22248.1 - 0.076 12.4 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_11 PF13086.1 KOS22248.1 - 0.08 12.4 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 KOS22248.1 - 0.1 12.4 0.0 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase APS_kinase PF01583.15 KOS22248.1 - 0.14 11.8 0.0 9.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase KTI12 PF08433.5 KOS22248.1 - 0.16 11.1 0.0 0.91 8.6 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 GDC-P PF02347.11 KOS22248.1 - 0.19 10.3 2.6 0.36 9.4 1.8 1.4 1 0 0 1 1 1 0 Glycine cleavage system P-protein APC10 PF03256.11 KOS22249.1 - 9.4e-31 106.9 0.0 1.5e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Asp PF00026.18 KOS22250.1 - 5.7e-54 183.5 0.0 6.6e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KOS22250.1 - 5.3e-06 26.4 0.0 2.7e-05 24.1 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KOS22250.1 - 5e-05 22.8 0.0 0.0001 21.9 0.0 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KOS22250.1 - 0.021 15.2 0.1 3.8 8.0 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.1 KOS22250.1 - 0.053 13.3 0.0 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Nop PF01798.13 KOS22251.1 - 2e-55 186.2 0.8 3.2e-55 185.5 0.6 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KOS22251.1 - 1.2e-25 89.0 0.2 2.1e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KOS22251.1 - 6.2e-22 77.5 0.9 2.2e-21 75.7 0.7 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Band_7 PF01145.20 KOS22252.1 - 3.8e-26 92.0 1.7 6.1e-26 91.4 1.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ribosomal_S15 PF00312.17 KOS22253.1 - 1.7e-17 62.9 4.7 6.4e-16 57.8 0.3 2.5 2 1 0 2 2 2 2 Ribosomal protein S15 CPSF73-100_C PF11718.3 KOS22253.1 - 0.25 10.6 2.7 0.21 10.9 0.5 1.7 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term vATP-synt_AC39 PF01992.11 KOS22254.1 - 9.7e-113 376.6 0.0 1.1e-112 376.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit SMC_Nse1 PF07574.8 KOS22254.1 - 0.09 12.3 0.0 0.59 9.7 0.0 2.1 2 0 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex RasGEF_N PF00618.15 KOS22255.1 - 2.5e-13 50.0 0.9 6e-13 48.8 0.6 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF755 PF05501.6 KOS22255.1 - 6.6 6.8 13.8 14 5.7 9.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ribosomal_S2 PF00318.15 KOS22256.1 - 7.7e-43 146.1 0.0 1.3e-22 80.0 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 DAGK_cat PF00781.19 KOS22257.1 - 2e-26 91.9 0.0 3e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Phosphoesterase PF04185.9 KOS22258.1 - 3.8e-55 187.6 6.1 5.9e-55 186.9 4.2 1.3 1 0 0 1 1 1 1 Phosphoesterase family GDC-P PF02347.11 KOS22258.1 - 0.16 10.6 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein dCMP_cyt_deam_1 PF00383.17 KOS22259.1 - 2.7e-15 55.8 0.0 6.2e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KOS22259.1 - 0.07 12.9 0.4 0.07 12.9 0.3 3.3 2 2 0 2 2 2 0 Bd3614-like deaminase TRAM_LAG1_CLN8 PF03798.11 KOS22260.1 - 8.1e-40 136.4 18.9 8.1e-40 136.4 13.1 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KOS22260.1 - 2.1e-17 62.3 1.1 6.6e-17 60.7 0.7 1.9 1 0 0 1 1 1 1 TRAM1-like protein SLT PF01464.15 KOS22261.1 - 0.0024 17.3 0.1 0.0045 16.4 0.0 1.5 2 0 0 2 2 2 1 Transglycosylase SLT domain MFS_1 PF07690.11 KOS22262.1 - 1.1e-29 103.2 23.0 1.9e-29 102.4 15.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily HhH-GPD PF00730.20 KOS22262.1 - 1.2e-17 64.0 0.0 2.7e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 KOS22262.1 - 2.7e-10 39.6 0.0 5.7e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain HHH_5 PF14520.1 KOS22262.1 - 0.049 13.8 0.2 0.27 11.4 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH PF00633.18 KOS22262.1 - 0.1 12.3 0.1 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Glypican PF01153.14 KOS22262.1 - 8.4 4.8 6.6 15 4.0 4.6 1.3 1 0 0 1 1 1 0 Glypican Cofilin_ADF PF00241.15 KOS22263.1 - 1.3e-15 57.3 0.0 1.5e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1641 PF07849.6 KOS22263.1 - 0.076 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) AA_permease_2 PF13520.1 KOS22264.1 - 1.2e-46 159.2 52.3 1.5e-46 158.8 36.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KOS22264.1 - 1.6e-30 105.9 47.8 2e-30 105.5 33.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2592 PF10766.4 KOS22264.1 - 0.12 11.7 3.9 0.73 9.2 1.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2592) GAPT PF11770.3 KOS22264.1 - 0.2 11.2 0.3 0.47 10.1 0.2 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) DUF4244 PF14029.1 KOS22264.1 - 0.23 10.5 2.9 0.33 10.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) CBM_21 PF03370.8 KOS22265.1 - 1.6e-33 115.0 0.9 3.8e-33 113.8 0.6 1.6 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit PX PF00787.19 KOS22266.1 - 7e-23 80.5 0.0 1.1e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 PX domain Pkinase PF00069.20 KOS22267.1 - 1.4e-28 99.8 0.0 1.6e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS22267.1 - 1.9e-17 63.2 0.0 2.1e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3328 PF11807.3 KOS22268.1 - 5.7e-45 153.6 0.2 7.4e-45 153.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Thioredoxin_2 PF13098.1 KOS22269.1 - 2.9e-05 24.2 0.2 0.81 9.9 0.1 4.0 1 1 0 1 1 1 1 Thioredoxin-like domain HHV6-IE PF03753.8 KOS22269.1 - 0.029 11.9 0.4 0.24 8.8 0.3 2.2 1 1 0 1 1 1 0 Human herpesvirus 6 immediate early protein PRP38_assoc PF12871.2 KOS22269.1 - 7.3 7.2 6.8 14 6.2 1.3 2.4 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term adh_short PF00106.20 KOS22270.1 - 3.2e-30 105.2 9.8 4.9e-30 104.6 6.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS22270.1 - 3.6e-20 72.7 0.8 4.8e-20 72.3 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS22270.1 - 7.5e-15 55.0 7.2 1.1e-14 54.5 5.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KOS22270.1 - 3.7e-07 29.8 1.0 2.5e-06 27.0 0.7 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KOS22270.1 - 5.7e-06 26.4 3.9 1.4e-05 25.2 2.7 1.6 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KOS22270.1 - 0.001 18.7 1.7 0.0021 17.7 1.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KOS22270.1 - 0.0014 17.5 0.1 0.0025 16.7 0.1 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 KOS22270.1 - 0.0018 17.3 0.2 0.0041 16.2 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 KOS22270.1 - 0.0026 17.4 1.1 0.0048 16.5 0.8 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NmrA PF05368.8 KOS22270.1 - 0.011 14.9 2.6 0.096 11.9 1.4 2.2 2 0 0 2 2 2 0 NmrA-like family DUF460 PF04312.8 KOS22270.1 - 0.023 14.2 0.7 0.051 13.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF460) ApbA PF02558.11 KOS22270.1 - 0.025 13.9 0.1 0.056 12.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.2 KOS22270.1 - 9.6 5.1 8.6 15 4.5 6.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AMP-binding PF00501.23 KOS22271.1 - 3.4e-75 253.0 0.0 5.8e-75 252.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KOS22271.1 - 2.1e-62 210.2 0.0 3e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KOS22271.1 - 1.5e-12 47.4 0.0 3.6e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KOS22271.1 - 9.8e-12 44.9 0.0 2.7e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KOS22271.1 - 2.6e-08 34.6 0.3 1.1e-07 32.6 0.2 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.12 KOS22271.1 - 4.1e-07 29.1 0.2 4.7e-06 25.7 0.0 2.4 3 0 0 3 3 3 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KOS22271.1 - 0.0004 19.1 0.0 0.0034 16.1 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KOS22271.1 - 0.016 14.1 0.0 0.043 12.7 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3328 PF11807.3 KOS22272.1 - 4.3e-26 91.9 0.0 5.4e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 KOS22273.1 - 5.1e-13 49.2 0.5 1e-12 48.2 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) RhoGEF PF00621.15 KOS22274.1 - 0.012 15.4 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 RhoGEF domain PRTP PF01366.13 KOS22274.1 - 0.077 10.9 0.1 0.098 10.6 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Zn_clus PF00172.13 KOS22275.1 - 0.0009 19.0 4.2 0.0014 18.4 2.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2638 PF10937.3 KOS22275.1 - 0.16 13.0 1.3 0.19 12.7 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2638) RdRP PF05183.7 KOS22276.1 - 1.2e-58 199.2 0.0 1.7e-57 195.4 0.0 2.1 1 1 1 2 2 2 1 RNA dependent RNA polymerase PilJ PF13675.1 KOS22276.1 - 0.12 12.7 0.1 0.33 11.2 0.1 1.8 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term zf-C3HC4_3 PF13920.1 KOS22277.1 - 0.0032 17.1 6.0 0.0064 16.1 4.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS22277.1 - 0.0051 16.8 7.5 0.011 15.7 4.9 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS22277.1 - 0.0076 15.9 10.2 0.031 14.0 6.1 2.3 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KOS22277.1 - 0.014 15.2 7.1 0.12 12.2 1.1 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KOS22277.1 - 0.029 14.2 6.8 0.029 14.2 4.7 1.6 2 0 0 2 2 2 0 Ring finger domain FYVE_2 PF02318.11 KOS22277.1 - 0.073 12.9 0.6 0.11 12.4 0.4 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger SBP56 PF05694.6 KOS22277.1 - 0.17 10.3 0.1 0.19 10.2 0.1 1.1 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) Prok-RING_4 PF14447.1 KOS22277.1 - 0.2 11.2 4.4 0.41 10.2 3.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-B_box PF00643.19 KOS22277.1 - 0.54 10.1 4.9 1.3 9.0 3.4 1.6 1 0 0 1 1 1 0 B-box zinc finger FYVE PF01363.16 KOS22277.1 - 1.2 9.1 8.2 3.6 7.5 5.9 1.7 1 1 1 2 2 2 0 FYVE zinc finger zf-C3HC4 PF00097.20 KOS22277.1 - 6.4 6.5 11.1 8.8 6.0 6.0 2.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KOS22277.1 - 9.2 6.0 9.2 3.3 7.5 4.1 2.0 2 1 1 3 3 3 0 RING-type zinc-finger tRNA_U5-meth_tr PF05958.6 KOS22278.1 - 2.4e-13 49.5 0.0 4.5e-12 45.3 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.5 KOS22278.1 - 6.1e-09 35.6 0.0 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 KOS22278.1 - 8e-09 35.2 0.0 1.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS22278.1 - 0.0001 22.3 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 KOS22278.1 - 0.00015 21.4 0.1 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_18 PF12847.2 KOS22278.1 - 0.00031 21.3 0.0 0.00066 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS22278.1 - 0.0044 16.4 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 KOS22278.1 - 0.0079 16.6 0.0 0.032 14.7 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KOS22278.1 - 0.0086 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.8 KOS22278.1 - 0.031 13.4 0.1 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 KOS22278.1 - 0.044 14.1 0.0 0.099 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 KOS22278.1 - 0.047 13.2 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TRM PF02005.11 KOS22278.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_12 PF08242.7 KOS22278.1 - 0.15 12.5 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain G_glu_transpept PF01019.16 KOS22279.1 - 1.5e-157 525.1 0.0 1.7e-157 524.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Glycos_transf_1 PF00534.15 KOS22280.1 - 1.5e-21 76.5 0.0 3.2e-21 75.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KOS22280.1 - 3.7e-11 43.3 0.1 3.5e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KOS22280.1 - 0.00022 20.9 0.0 0.00058 19.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Pribosyl_synth PF14572.1 KOS22281.1 - 1.7e-44 151.7 2.4 1.9e-38 132.0 0.5 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KOS22281.1 - 2.8e-29 101.1 0.0 1.5e-28 98.8 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KOS22281.1 - 1.4e-11 44.1 0.1 3.4e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain AviRa PF11599.3 KOS22281.1 - 0.051 12.5 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa UPRTase PF14681.1 KOS22281.1 - 0.11 11.6 0.1 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Actin PF00022.14 KOS22282.1 - 2.6e-86 289.5 0.0 6.1e-86 288.2 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KOS22282.1 - 0.01 14.4 0.0 2.6 6.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Asparaginase_2 PF01112.13 KOS22283.1 - 1.9e-14 53.1 2.9 2.4e-14 52.7 2.0 1.1 1 0 0 1 1 1 1 Asparaginase PP2C PF00481.16 KOS22283.1 - 0.042 13.2 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C Tfb4 PF03850.9 KOS22284.1 - 1.7e-92 309.6 0.2 2.1e-92 309.3 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C2HC5 PF06221.8 KOS22284.1 - 0.042 13.6 5.1 0.072 12.8 3.5 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type UNC45-central PF11701.3 KOS22285.1 - 6.3e-47 159.1 0.1 5.1e-45 152.9 0.0 3.1 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 KOS22285.1 - 1.9e-05 24.8 11.5 0.016 15.4 0.6 6.2 4 2 2 6 6 6 3 HEAT repeats HMA PF00403.21 KOS22286.1 - 6.3e-13 48.6 1.6 1.5e-12 47.4 0.3 1.8 1 1 1 2 2 2 1 Heavy-metal-associated domain Toxin-deaminase PF14424.1 KOS22286.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Thiolase_C PF02803.13 KOS22287.1 - 7.4e-11 41.5 0.1 7.4e-11 41.5 0.1 2.8 2 1 0 2 2 2 1 Thiolase, C-terminal domain Ketoacyl-synt_C PF02801.17 KOS22287.1 - 9.9e-05 22.1 1.6 0.015 15.1 0.0 3.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.5 KOS22287.1 - 0.00021 20.8 0.1 0.023 14.3 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KOS22287.1 - 0.0038 16.2 2.0 0.032 13.2 0.2 2.8 3 1 0 3 3 3 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.1 KOS22288.1 - 4.4e-14 52.5 0.0 6.7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS22288.1 - 9.8e-10 38.8 0.0 2.4e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS22288.1 - 3.5e-09 37.2 0.0 5.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS22288.1 - 4e-09 36.8 0.0 6.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KOS22288.1 - 1.5e-08 34.0 0.0 3.4e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KOS22288.1 - 2.4e-08 33.6 0.0 5.9e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS22288.1 - 5e-08 33.2 0.0 1.1e-07 32.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS22288.1 - 0.0001 22.3 0.2 0.00052 20.0 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS22288.1 - 0.036 13.4 0.0 0.081 12.2 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.1 KOS22288.1 - 0.051 13.2 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Epiglycanin_C PF14654.1 KOS22288.1 - 6.1 6.9 9.3 12 5.9 6.4 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Acetyltransf_1 PF00583.19 KOS22289.1 - 3.5e-11 42.9 0.0 6.8e-11 42.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS22289.1 - 3.7e-10 39.8 0.1 5.3e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS22289.1 - 0.00035 20.4 0.0 0.00042 20.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS22289.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C3HC4_4 PF15227.1 KOS22289.1 - 0.11 12.3 2.6 3.3 7.6 0.8 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Pkinase PF00069.20 KOS22290.1 - 0.00046 19.4 0.0 0.00087 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain UBA_4 PF14555.1 KOS22291.1 - 1.3e-08 34.2 0.0 2.4e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KOS22291.1 - 1.1e-06 28.5 0.0 2.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 UBX domain SUFU_C PF12470.3 KOS22291.1 - 0.014 14.9 0.3 0.022 14.3 0.2 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain Rod_cone_degen PF15201.1 KOS22291.1 - 0.1 12.4 0.4 0.36 10.6 0.3 1.9 2 0 0 2 2 2 0 Progressive rod-cone degeneration Selenoprotein_S PF06936.6 KOS22291.1 - 0.73 9.3 7.3 1.4 8.4 5.1 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) Zn_clus PF00172.13 KOS22292.1 - 0.0035 17.2 10.8 0.0061 16.4 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.17 KOS22293.1 - 3.5e-18 64.8 0.2 4.6e-18 64.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 KOS22293.1 - 1.3 9.4 11.8 1.5 9.3 7.7 1.4 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Peptidase_M43 PF05572.8 KOS22294.1 - 1.9e-16 60.0 0.1 3.3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 KOS22294.1 - 0.002 18.1 0.6 0.0039 17.2 0.4 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KOS22294.1 - 0.0021 17.6 0.1 0.0042 16.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KOS22294.1 - 0.0065 16.4 0.3 0.012 15.5 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 KOS22294.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Matrixin Peptidase_M7 PF02031.11 KOS22294.1 - 0.14 11.9 0.1 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Mito_carr PF00153.22 KOS22295.1 - 5e-76 250.5 1.3 8.5e-25 86.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein KxDL PF10241.4 KOS22295.1 - 0.076 12.9 0.1 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein UPRTase PF14681.1 KOS22296.1 - 1.2e-29 103.0 0.1 2.2e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KOS22296.1 - 4e-06 26.5 2.5 0.00053 19.7 1.8 2.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain AAA_17 PF13207.1 KOS22296.1 - 5.5e-05 23.9 0.0 0.00013 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Hydrolase PF00702.21 KOS22296.1 - 0.00024 21.6 0.1 0.0033 17.8 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_18 PF13238.1 KOS22296.1 - 0.00076 19.7 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain HAD PF12710.2 KOS22296.1 - 0.0024 18.0 0.0 0.026 14.7 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KOS22296.1 - 0.0028 17.2 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PRTase_2 PF15609.1 KOS22296.1 - 0.0099 15.2 0.5 0.048 12.9 0.4 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase KAP_NTPase PF07693.9 KOS22296.1 - 0.089 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_33 PF13671.1 KOS22296.1 - 0.15 11.9 1.0 0.8 9.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain F-box PF00646.28 KOS22297.1 - 0.047 13.3 0.2 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 F-box domain CoA_transf_3 PF02515.12 KOS22298.1 - 4.6e-39 133.6 7.3 4.6e-39 133.6 5.1 3.5 4 1 0 4 4 4 2 CoA-transferase family III Robl_LC7 PF03259.12 KOS22298.1 - 9 5.9 7.5 6.6 6.3 0.3 2.9 3 0 0 3 3 3 0 Roadblock/LC7 domain MFS_1 PF07690.11 KOS22299.1 - 0.00013 20.8 6.0 0.00013 20.8 4.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2269 PF10027.4 KOS22299.1 - 0.043 13.5 0.2 0.088 12.5 0.1 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) A-2_8-polyST PF07388.6 KOS22299.1 - 0.15 10.4 0.0 0.22 9.8 0.0 1.3 1 1 0 1 1 1 0 Alpha-2,8-polysialyltransferase (POLYST) DUF706 PF05153.10 KOS22300.1 - 2.4e-116 387.4 0.0 3.3e-116 387.0 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF706) DUF953 PF06110.6 KOS22301.1 - 1.4e-10 40.6 0.1 1.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 KOS22301.1 - 0.015 14.9 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.19 KOS22301.1 - 0.041 13.8 0.1 0.051 13.5 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin ABC_tran PF00005.22 KOS22302.1 - 1e-18 67.9 0.0 2e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KOS22302.1 - 1.8e-05 24.2 5.3 2.4e-05 23.9 3.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KOS22302.1 - 0.00041 20.4 0.0 0.00071 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS22302.1 - 0.00095 19.9 0.0 0.0019 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KOS22302.1 - 0.0012 18.0 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KOS22302.1 - 0.0031 17.0 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KOS22302.1 - 0.012 14.7 0.1 0.023 13.7 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.1 KOS22302.1 - 0.037 14.3 0.0 0.068 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KOS22302.1 - 0.043 14.1 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KOS22302.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_28 PF13521.1 KOS22302.1 - 0.13 12.2 0.4 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain TPR_11 PF13414.1 KOS22303.1 - 1.8e-22 78.7 6.1 8.5e-17 60.5 2.3 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KOS22303.1 - 1.2e-20 72.2 1.7 2.6e-08 33.1 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS22303.1 - 8e-18 62.8 2.7 2.1e-06 27.2 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KOS22303.1 - 3.4e-11 42.7 2.6 0.00038 20.8 0.3 3.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KOS22303.1 - 2.8e-10 40.6 6.0 2.8e-07 31.0 1.1 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KOS22303.1 - 2.4e-09 36.6 1.8 0.0042 17.1 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KOS22303.1 - 6.9e-08 31.7 0.1 0.014 15.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS22303.1 - 2.7e-07 30.8 2.0 0.0024 18.1 0.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KOS22303.1 - 3.6e-07 30.0 3.3 0.0037 17.1 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KOS22303.1 - 6.2e-06 25.6 2.1 0.01 15.5 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 KOS22303.1 - 0.00032 20.4 1.2 0.026 14.3 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KOS22303.1 - 0.00054 20.2 0.7 1.3 9.5 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KOS22303.1 - 0.00059 19.9 0.6 0.065 13.3 0.0 2.6 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 KOS22303.1 - 0.0015 18.8 3.7 0.0049 17.1 1.0 2.4 2 1 0 2 2 1 1 Bacterial transcriptional activator domain XPC-binding PF09280.6 KOS22303.1 - 0.006 16.0 1.2 0.016 14.6 0.8 1.7 1 0 0 1 1 1 1 XPC-binding domain MIT PF04212.13 KOS22303.1 - 0.044 13.6 1.0 2.2 8.2 0.2 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 KOS22303.1 - 0.34 10.9 4.4 17 5.5 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RINGv PF12906.2 KOS22304.1 - 0.00044 20.2 8.9 0.00074 19.5 6.2 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KOS22304.1 - 0.0035 17.1 9.5 0.0056 16.4 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain Pex14_N PF04695.8 KOS22304.1 - 0.0095 15.9 0.7 0.02 14.9 0.5 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region FANCL_C PF11793.3 KOS22304.1 - 0.21 11.6 5.8 0.41 10.6 4.0 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.2 KOS22304.1 - 0.28 11.3 4.3 0.59 10.2 3.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 KOS22304.1 - 0.47 10.0 9.0 0.84 9.2 6.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Lin-8 PF03353.10 KOS22304.1 - 0.48 9.6 4.5 0.7 9.1 3.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-C3HC4_3 PF13920.1 KOS22304.1 - 1.8 8.2 6.9 3.1 7.5 4.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS22304.1 - 4.4 7.0 8.3 7 6.4 5.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FimP PF09766.4 KOS22304.1 - 7.4 5.5 10.3 11 4.9 7.2 1.2 1 0 0 1 1 1 0 Fms-interacting protein DUF4175 PF13779.1 KOS22304.1 - 9.5 3.7 19.1 14 3.2 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) GalKase_gal_bdg PF10509.4 KOS22305.1 - 1.8e-20 71.9 0.2 3.3e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 KOS22305.1 - 1.5e-14 53.9 0.1 3.8e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 KOS22305.1 - 1e-09 38.3 1.4 1e-09 38.3 1.0 2.3 3 0 0 3 3 3 1 GHMP kinases N terminal domain Sigma70_r4_2 PF08281.7 KOS22305.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 TPP_enzyme_N PF02776.13 KOS22306.1 - 3.6e-57 192.5 0.1 3.6e-56 189.3 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KOS22306.1 - 5.3e-49 165.7 0.8 1.8e-47 160.7 0.1 2.9 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KOS22306.1 - 1.8e-37 128.1 1.5 1.5e-36 125.2 0.3 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 KOS22306.1 - 0.042 13.3 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF629 PF04780.7 KOS22307.1 - 0.032 12.7 0.5 0.064 11.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Mito_carr PF00153.22 KOS22308.1 - 1.1e-25 89.1 2.8 2.2e-14 52.9 0.1 3.5 3 1 0 3 3 3 2 Mitochondrial carrier protein Thr_synth_N PF14821.1 KOS22309.1 - 6.3e-28 96.6 0.0 2.3e-27 94.8 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 KOS22309.1 - 1.3e-20 73.8 0.0 2.8e-20 72.7 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-CCCH PF00642.19 KOS22310.1 - 3.3e-06 26.6 0.7 3.3e-06 26.6 0.5 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mito_carr PF00153.22 KOS22311.1 - 1.2e-13 50.5 0.0 1.6e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Sbi-IV PF11621.3 KOS22312.1 - 0.031 14.4 0.1 0.076 13.1 0.0 1.7 1 0 0 1 1 1 0 C3 binding domain 4 of IgG-bind protein SBI Ras PF00071.17 KOS22313.1 - 3.8e-65 218.1 0.7 4.5e-65 217.9 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS22313.1 - 3.3e-21 75.9 0.0 5.2e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS22313.1 - 1.7e-16 59.9 0.1 2.1e-16 59.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KOS22313.1 - 1e-05 24.8 0.1 1.3e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KOS22313.1 - 1.8e-05 24.2 0.2 3.7e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KOS22313.1 - 6.1e-05 22.9 0.1 0.00011 22.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KOS22313.1 - 0.00029 20.0 0.1 0.00042 19.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KOS22313.1 - 0.00077 19.6 0.0 0.0013 18.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KOS22313.1 - 0.0017 18.5 0.1 0.36 11.0 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 KOS22313.1 - 0.0037 16.5 0.1 0.025 13.8 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KOS22313.1 - 0.0066 15.6 0.2 0.024 13.8 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 KOS22313.1 - 0.015 15.1 0.2 0.039 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KOS22313.1 - 0.015 15.2 0.0 0.058 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 KOS22313.1 - 0.035 13.6 0.0 0.095 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KOS22313.1 - 0.058 13.1 0.0 0.077 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KOS22313.1 - 0.081 13.2 0.0 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter WD40 PF00400.27 KOS22314.1 - 1.2e-20 72.5 3.5 0.00012 21.7 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF3639 PF12341.3 KOS22314.1 - 3.2e-08 33.4 3.0 6.3e-08 32.4 1.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 KOS22314.1 - 3.6e-05 22.7 0.0 0.00097 18.0 0.0 2.0 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 KOS22314.1 - 0.00062 19.5 0.0 0.0084 15.8 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 KOS22314.1 - 0.049 13.1 0.0 3 7.4 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain CDC45 PF02724.9 KOS22314.1 - 4.8 5.0 9.3 7.7 4.4 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 KOS22314.1 - 9.8 5.6 9.4 36 3.8 6.8 1.7 2 0 0 2 2 2 0 Nucleoplasmin WD40 PF00400.27 KOS22315.1 - 2.1e-18 65.4 10.8 0.00013 21.6 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KOS22315.1 - 9.5e-05 21.9 5.9 0.00074 19.0 4.1 2.3 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 KOS22315.1 - 0.0087 14.2 1.2 0.079 11.0 0.0 2.5 2 1 1 3 3 3 1 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KOS22315.1 - 0.013 15.7 5.0 0.064 13.5 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain Sigma70_r1_2 PF00140.15 KOS22315.1 - 0.051 13.2 0.9 0.097 12.3 0.6 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 CS PF04969.11 KOS22316.1 - 2.7e-07 31.0 0.1 4.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 CS domain RRM_1 PF00076.17 KOS22317.1 - 3.2e-15 55.5 0.0 5.7e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS22317.1 - 1.1e-11 44.4 0.0 1.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS22317.1 - 5.4e-08 32.5 0.0 9.3e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KOS22317.1 - 0.0002 21.7 2.3 0.0002 21.7 1.6 2.7 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 DUF2404 PF10296.4 KOS22318.1 - 5.4e-30 103.3 0.0 1.2e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 KOS22318.1 - 0.043 14.0 0.0 0.22 11.7 0.0 2.2 2 1 0 2 2 2 0 PH domain Gastrin PF00918.12 KOS22318.1 - 1.3 9.8 5.1 30 5.4 0.0 2.9 2 0 0 2 2 2 0 Gastrin/cholecystokinin family Mcp5_PH PF12814.2 KOS22320.1 - 7.7e-42 142.0 0.0 1.5e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology IncA PF04156.9 KOS22320.1 - 0.16 11.5 53.0 0.42 10.1 0.7 5.1 3 1 2 5 5 5 0 IncA protein DUF2465 PF10239.4 KOS22321.1 - 0.097 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) Ribosomal_L21e PF01157.13 KOS22322.1 - 9.2e-41 137.6 6.0 1.1e-40 137.3 3.6 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e DUF3865 PF12981.2 KOS22322.1 - 0.067 12.9 0.1 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) Ribosomal_S4 PF00163.14 KOS22323.1 - 4.7e-28 97.4 1.0 9.8e-28 96.3 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KOS22323.1 - 8.1e-13 47.5 0.7 8.1e-13 47.5 0.5 2.6 3 0 0 3 3 3 1 S4 domain Slu7 PF11708.3 KOS22324.1 - 4.2e-70 236.2 11.7 4.2e-70 236.2 8.1 2.3 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 KOS22324.1 - 0.018 14.6 1.1 0.037 13.6 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 KOS22324.1 - 0.094 12.6 1.0 0.18 11.7 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Alpha-amylase PF00128.19 KOS22324.1 - 0.17 11.2 0.1 0.17 11.2 0.1 2.5 2 1 0 3 3 3 0 Alpha amylase, catalytic domain DNA_pol_B PF00136.16 KOS22325.1 - 1.3e-96 324.1 0.0 1.9e-96 323.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.1 KOS22325.1 - 3.9e-17 62.0 5.1 8.3e-17 60.9 3.5 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo1 PF03104.14 KOS22325.1 - 3.4e-09 36.0 0.0 6.4e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain Ribosomal_S14 PF00253.16 KOS22325.1 - 0.012 14.9 0.6 0.036 13.4 0.4 1.8 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e DNA_pol_B_2 PF03175.8 KOS22325.1 - 0.1 11.2 0.5 0.17 10.5 0.3 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral FYVE PF01363.16 KOS22325.1 - 0.13 12.1 3.1 0.27 11.1 2.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger Exo_endo_phos_2 PF14529.1 KOS22326.1 - 4.5e-20 71.4 0.0 1.9e-19 69.4 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KOS22326.1 - 7.7e-18 65.3 0.0 1.1e-17 64.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family I_LWEQ PF01608.12 KOS22327.1 - 6.7e-64 214.4 7.7 6.7e-64 214.4 5.3 5.6 4 1 1 6 6 6 2 I/LWEQ domain ANTH PF07651.11 KOS22327.1 - 6.9e-52 175.8 2.1 6.9e-52 175.8 1.4 3.3 1 1 1 2 2 2 1 ANTH domain ISN1 PF06437.6 KOS22328.1 - 3.5e-180 599.0 0.0 5.1e-180 598.5 0.0 1.2 1 1 0 1 1 1 1 IMP-specific 5'-nucleotidase PV-1 PF06637.6 KOS22328.1 - 0.03 12.8 0.0 0.055 12.0 0.0 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) IBN_N PF03810.14 KOS22329.1 - 2.2e-12 46.7 7.6 3.5e-11 42.8 0.0 4.2 4 0 0 4 4 4 2 Importin-beta N-terminal domain Cse1 PF08506.5 KOS22329.1 - 2.1e-08 33.1 0.0 7.7e-08 31.2 0.0 2.0 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.7 KOS22329.1 - 1.1e-05 25.3 4.1 4.7e-05 23.3 0.4 3.5 4 0 0 4 4 4 1 Exportin 1-like protein Katanin_con80 PF13925.1 KOS22329.1 - 0.025 14.3 0.3 0.21 11.2 0.0 2.7 3 0 0 3 3 3 0 con80 domain of Katanin IMS PF00817.15 KOS22331.1 - 7.2e-42 142.7 0.0 1.1e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KOS22331.1 - 1.8e-12 47.2 0.0 3.8e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KOS22331.1 - 0.003 17.5 1.0 0.006 16.5 0.0 2.0 2 0 0 2 2 2 1 IMS family HHH motif TFIIA PF03153.8 KOS22332.1 - 8.7e-05 22.5 5.5 0.00013 21.9 3.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FlgN PF05130.7 KOS22332.1 - 0.051 13.8 3.3 0.097 12.9 2.3 1.5 1 0 0 1 1 1 0 FlgN protein Herpes_BLRF2 PF05812.7 KOS22332.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein TPR_MLP1_2 PF07926.7 KOS22332.1 - 0.47 10.1 5.9 1.2 8.9 4.1 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Ank_2 PF12796.2 KOS22333.1 - 2.8e-12 46.8 0.1 1.7e-06 28.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) F-box-like PF12937.2 KOS22333.1 - 7e-06 25.6 0.1 1.5e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like Ank_4 PF13637.1 KOS22333.1 - 3.6e-05 24.1 1.6 0.32 11.5 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KOS22333.1 - 6.4e-05 23.0 1.8 0.49 10.7 0.0 3.5 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KOS22333.1 - 0.00056 19.5 0.5 0.8 9.6 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 KOS22333.1 - 0.0046 17.0 0.7 1.5 9.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat F-box-like_2 PF13013.1 KOS22333.1 - 0.12 12.1 0.6 0.32 10.7 0.4 1.8 1 1 0 1 1 1 0 F-box-like domain Pkinase PF00069.20 KOS22334.1 - 2.1e-54 184.4 0.0 3.1e-54 183.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS22334.1 - 4.3e-26 91.5 0.2 2.2e-25 89.1 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS22334.1 - 0.018 14.0 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-C3HC4_3 PF13920.1 KOS22336.1 - 1.1e-08 34.5 4.5 1.8e-08 33.9 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS22336.1 - 5.5e-08 32.7 10.0 9.7e-08 31.9 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 KOS22336.1 - 1.6e-07 30.8 1.9 2.9e-07 29.9 1.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.20 KOS22336.1 - 3e-07 29.9 9.8 5.1e-07 29.2 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS22336.1 - 4e-06 26.5 7.0 6.6e-06 25.8 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KOS22336.1 - 4.3e-06 26.3 7.9 7e-06 25.6 5.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KOS22336.1 - 0.00072 19.3 8.9 0.0015 18.3 6.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KOS22336.1 - 0.012 15.2 5.4 0.028 14.1 3.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 KOS22336.1 - 1.3 9.1 6.4 3.7 7.7 4.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Autophagy_N PF03986.8 KOS22337.1 - 6.2e-47 159.0 0.8 7.3e-47 158.8 0.0 1.5 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KOS22337.1 - 7.1e-23 80.5 0.2 1.6e-22 79.4 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KOS22337.1 - 1.3e-14 52.9 0.4 2.5e-14 52.0 0.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal ADP_ribosyl_GH PF03747.9 KOS22338.1 - 4.2e-61 207.2 0.2 5e-61 207.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Abhydrolase_6 PF12697.2 KOS22339.1 - 5.3e-11 42.8 1.2 5.3e-11 42.8 0.8 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS22339.1 - 6.3e-11 42.2 0.1 1.2e-09 38.1 0.1 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS22339.1 - 0.0072 15.5 0.1 0.035 13.3 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KOS22339.1 - 0.012 15.1 0.1 0.051 13.1 0.1 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 KOS22339.1 - 0.017 14.4 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.6 KOS22339.1 - 0.032 13.9 0.0 0.078 12.6 0.0 1.6 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 KOS22339.1 - 0.15 11.4 0.0 0.4 10.0 0.0 1.6 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 KOS22339.1 - 0.17 10.3 0.2 0.97 7.8 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Ras PF00071.17 KOS22340.1 - 1.4e-50 170.8 0.0 1.6e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS22340.1 - 9.3e-17 61.6 0.0 1.2e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS22340.1 - 2.2e-06 27.0 0.0 3.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KOS22340.1 - 0.0068 15.5 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KOS22340.1 - 0.014 14.6 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KOS22340.1 - 0.025 14.0 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 KOS22340.1 - 0.059 13.3 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KOS22340.1 - 0.079 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3446 PF11928.3 KOS22341.1 - 5.5 7.2 8.0 12 6.1 5.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3446) OCC1 PF15506.1 KOS22342.1 - 2.4 8.1 5.9 3.3 7.6 0.3 3.0 2 1 1 3 3 3 0 OCC1 family Pkinase PF00069.20 KOS22343.1 - 1.4e-58 198.1 0.0 1.8e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS22343.1 - 8.4e-33 113.5 0.0 1.3e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS22343.1 - 2.7e-05 23.3 0.0 5.8e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KOS22343.1 - 0.0084 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KOS22343.1 - 0.017 13.9 0.6 0.026 13.3 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KOS22343.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF805 PF05656.9 KOS22344.1 - 0.028 14.2 1.1 0.038 13.8 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) RRM_1 PF00076.17 KOS22345.1 - 0.026 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS22345.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_1 PF00583.19 KOS22346.1 - 6.7e-12 45.2 0.2 1.2e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KOS22346.1 - 8.6e-09 35.5 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KOS22346.1 - 2.4e-07 30.8 0.0 3.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KOS22346.1 - 3.4e-06 26.7 0.0 5.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KOS22346.1 - 0.0034 17.2 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS22346.1 - 0.0095 15.7 0.1 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 KOS22346.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_4 PF13420.1 KOS22346.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Med15 PF09606.5 KOS22347.1 - 0.0026 16.0 18.0 0.0028 15.9 12.5 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2950 PF11453.3 KOS22347.1 - 0.03 13.3 2.4 0.034 13.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) Bud13 PF09736.4 KOS22347.1 - 0.11 12.6 4.4 0.14 12.4 3.0 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex FlxA PF14282.1 KOS22347.1 - 0.12 12.3 27.0 0.24 11.3 18.7 1.4 1 0 0 1 1 1 0 FlxA-like protein DUF4557 PF15101.1 KOS22347.1 - 0.18 11.6 5.5 0.19 11.5 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3373 PF11853.3 KOS22347.1 - 0.55 8.7 3.3 0.64 8.4 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) PAT1 PF09770.4 KOS22347.1 - 0.93 7.6 15.1 0.93 7.6 10.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.3 KOS22347.1 - 2.2 6.9 22.9 2.6 6.6 15.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 BAF1_ABF1 PF04684.8 KOS22347.1 - 8.4 5.1 19.6 10 4.8 13.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Lyase_1 PF00206.15 KOS22350.1 - 3.9e-87 292.3 0.0 5.5e-87 291.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KOS22350.1 - 1.4e-27 95.5 0.0 3.4e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal SHOCT PF09851.4 KOS22350.1 - 0.024 14.1 0.2 0.11 11.9 0.0 2.3 2 0 0 2 2 2 0 Short C-terminal domain GARS_A PF01071.14 KOS22351.1 - 1.3e-80 269.5 0.0 2.1e-80 268.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KOS22351.1 - 3.4e-35 120.4 0.0 9.5e-35 119.0 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KOS22351.1 - 2.7e-33 115.1 0.2 6.7e-33 113.8 0.2 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KOS22351.1 - 2.3e-23 82.1 0.1 1e-22 80.1 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KOS22351.1 - 7.2e-16 58.2 3.3 1.4e-15 57.3 1.3 2.4 2 0 0 2 2 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KOS22351.1 - 3.1e-09 36.8 0.0 9.2e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KOS22351.1 - 2.8e-06 26.3 0.0 5.1e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 KOS22351.1 - 4e-05 22.9 0.1 7.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 KOS22351.1 - 0.00038 19.8 0.0 0.0008 18.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.5 KOS22351.1 - 0.012 15.0 0.1 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 KOS22351.1 - 0.036 13.5 0.2 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain MFS_1 PF07690.11 KOS22352.1 - 4e-30 104.7 55.9 6.4e-25 87.6 24.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS22352.1 - 1.6e-13 50.1 28.5 2.5e-13 49.4 19.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1992 PF09350.5 KOS22353.1 - 3.2e-21 74.9 0.4 8.3e-21 73.5 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) PTR2 PF00854.16 KOS22354.1 - 1.7e-45 155.4 14.3 5.7e-45 153.6 9.9 1.9 1 1 0 1 1 1 1 POT family Fe-S_biosyn PF01521.15 KOS22355.1 - 1.3e-19 70.1 0.0 1.7e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.2 KOS22355.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) DNA_binding_1 PF01035.15 KOS22356.1 - 2.1e-24 85.0 0.0 8.5e-24 83.1 0.0 1.8 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Abhydrolase_4 PF08386.5 KOS22357.1 - 1.3e-19 69.9 0.1 3.2e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 KOS22357.1 - 2.2e-10 40.4 3.0 3.5e-10 39.8 1.9 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KOS22357.1 - 4.1e-07 30.1 3.6 1.9e-06 27.9 2.5 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ras PF00071.17 KOS22358.1 - 1.3e-42 144.9 0.0 1.7e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS22358.1 - 1.2e-13 51.5 0.0 1.1e-12 48.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KOS22358.1 - 1.1e-05 24.7 0.0 1.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KOS22358.1 - 0.00017 21.0 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Scytalone_dh PF02982.9 KOS22358.1 - 0.047 13.2 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase Tcp11 PF05794.8 KOS22359.1 - 1.2e-39 136.3 0.0 3.8e-39 134.6 0.0 1.8 2 1 0 2 2 2 1 T-complex protein 11 Mnd1 PF03962.10 KOS22359.1 - 9.1 5.8 8.7 11 5.6 5.0 1.9 2 0 0 2 2 2 0 Mnd1 family Y_phosphatase PF00102.22 KOS22360.1 - 9.7e-59 198.5 0.0 3.1e-51 174.0 0.0 2.9 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 KOS22360.1 - 3.9e-12 46.5 0.0 4.4e-11 43.1 0.0 2.7 3 0 0 3 3 3 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 KOS22360.1 - 0.026 14.7 0.1 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 KOS22360.1 - 0.062 12.8 0.4 0.13 11.8 0.3 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain RST PF12174.3 KOS22360.1 - 0.17 11.6 0.1 17 5.2 0.0 2.4 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain DUF1989 PF09347.5 KOS22361.1 - 4.9e-53 178.9 0.0 6.1e-53 178.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) AAA PF00004.24 KOS22362.1 - 9.7e-44 148.7 0.0 1.6e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS22362.1 - 1e-07 31.7 0.0 2.7e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KOS22362.1 - 4.9e-07 29.8 0.0 9.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KOS22362.1 - 2.7e-06 27.5 0.0 7.4e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KOS22362.1 - 1.2e-05 25.4 0.1 0.00061 19.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS22362.1 - 0.00011 21.8 0.1 0.00025 20.7 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KOS22362.1 - 0.00013 21.1 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KOS22362.1 - 0.00013 21.4 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 KOS22362.1 - 0.00028 21.6 0.1 0.00071 20.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KOS22362.1 - 0.0015 17.3 0.0 0.0027 16.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 KOS22362.1 - 0.0017 18.2 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KOS22362.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS22362.1 - 0.0021 17.1 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KOS22362.1 - 0.0034 16.8 0.1 0.013 14.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 KOS22362.1 - 0.0046 16.9 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KOS22362.1 - 0.0056 16.9 0.0 0.029 14.6 0.0 2.3 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 KOS22362.1 - 0.0056 15.8 0.1 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KOS22362.1 - 0.0057 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_3 PF07726.6 KOS22362.1 - 0.0065 16.0 0.0 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KOS22362.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 KOS22362.1 - 0.014 14.6 0.0 0.049 12.8 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 KOS22362.1 - 0.017 14.7 0.1 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KOS22362.1 - 0.021 14.2 0.0 0.097 12.1 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KOS22362.1 - 0.028 14.5 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KOS22362.1 - 0.049 13.2 0.0 0.28 10.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Histone PF00125.19 KOS22362.1 - 0.052 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sigma54_activ_2 PF14532.1 KOS22362.1 - 0.053 13.5 0.0 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KOS22362.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KOS22362.1 - 0.081 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2072 PF09845.4 KOS22362.1 - 0.096 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Na_Ca_ex PF01699.19 KOS22363.1 - 1.4e-32 112.2 22.6 4.6e-21 74.8 6.2 3.7 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KOS22363.1 - 4.9e-13 49.3 12.5 4.9e-13 49.3 8.7 3.7 2 0 0 2 2 2 1 Domain of unknown function (DUF307) TPPK_C PF12555.3 KOS22363.1 - 0.26 11.0 7.1 0.12 12.0 0.5 2.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Nucleoplasmin PF03066.10 KOS22363.1 - 3 7.3 12.4 7.1 6.1 8.6 1.6 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 KOS22363.1 - 3 5.6 16.2 4.5 5.0 11.2 1.2 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 KOS22363.1 - 5.2 4.7 7.6 7.9 4.2 5.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dicty_REP PF05086.7 KOS22363.1 - 6.4 4.4 6.4 9.2 3.8 4.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Clathrin PF00637.15 KOS22364.1 - 4.3e-22 78.2 1.9 6.7e-20 71.1 0.1 2.7 3 0 0 3 3 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 KOS22364.1 - 1.2e-15 57.0 0.0 2.9e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal TPR_11 PF13414.1 KOS22364.1 - 0.003 17.1 0.5 0.015 14.9 0.0 2.5 2 0 0 2 2 2 1 TPR repeat zf-RING_5 PF14634.1 KOS22364.1 - 0.0046 16.6 4.6 0.01 15.5 3.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KOS22364.1 - 0.0057 16.4 4.5 0.013 15.3 3.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KOS22364.1 - 0.015 14.9 4.2 0.042 13.5 2.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.1 KOS22364.1 - 0.034 14.7 3.9 30 5.6 0.0 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KOS22364.1 - 0.06 13.3 5.9 0.083 12.8 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat Leuk-A4-hydro_C PF09127.6 KOS22364.1 - 0.087 12.4 0.6 1.4 8.5 0.1 2.5 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal TPR_8 PF13181.1 KOS22364.1 - 0.099 12.4 0.5 0.8 9.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-Apc11 PF12861.2 KOS22364.1 - 0.1 12.4 0.3 0.24 11.2 0.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KOS22364.1 - 0.18 11.9 2.0 0.38 10.9 1.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger TPR_19 PF14559.1 KOS22364.1 - 0.29 11.5 7.3 0.61 10.4 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 KOS22364.1 - 1.2 9.2 7.8 0.85 9.7 2.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KOS22364.1 - 6.2 6.8 6.7 3.2 7.8 2.4 2.2 2 0 0 2 2 2 0 RING-like domain UPF0016 PF01169.14 KOS22367.1 - 9.9e-42 140.9 25.5 6.6e-21 74.2 5.5 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 KOS22367.1 - 0.0078 15.6 0.0 0.0078 15.6 0.0 2.4 2 1 0 2 2 2 1 Integral membrane protein TerC family RNA_pol_N PF01194.12 KOS22368.1 - 0.062 13.3 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit SET PF00856.23 KOS22369.1 - 8.8e-10 39.1 0.0 1.2e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 SET domain WD40 PF00400.27 KOS22370.1 - 9.1e-22 76.0 14.7 1.9e-07 30.6 1.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat PD40 PF07676.7 KOS22370.1 - 0.094 12.4 0.0 0.094 12.4 0.0 2.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TRP PF06011.7 KOS22372.1 - 1.8e-146 488.2 30.7 2.2e-146 487.9 21.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KOS22372.1 - 1.3e-39 135.4 0.4 2.2e-39 134.7 0.3 1.4 1 0 0 1 1 1 1 ML-like domain ATP-sulfurylase PF01747.12 KOS22373.1 - 7.4e-88 293.4 0.1 1e-87 292.9 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KOS22373.1 - 2.3e-56 189.8 0.0 3.5e-56 189.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KOS22373.1 - 2.1e-51 173.5 0.0 3.2e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 KOS22373.1 - 0.0061 16.4 0.2 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 KOS22373.1 - 0.059 12.9 0.1 0.68 9.5 0.0 2.2 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 KOS22373.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2058 PF09831.4 KOS22374.1 - 0.27 11.0 2.8 0.83 9.5 1.9 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF3439 PF11921.3 KOS22374.1 - 1.5 8.5 15.2 3.8 7.2 10.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 KOS22374.1 - 1.6 6.3 8.4 3 5.4 5.8 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PNP_UDP_1 PF01048.15 KOS22375.1 - 0.0001 21.3 0.3 0.00016 20.7 0.2 1.3 1 1 0 1 1 1 1 Phosphorylase superfamily RRM_6 PF14259.1 KOS22376.1 - 2.1e-09 37.1 0.0 3.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS22376.1 - 2.4e-06 27.0 0.0 4.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS22376.1 - 0.00013 21.6 0.1 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HIT PF01230.18 KOS22377.1 - 1.6e-16 60.5 0.0 2.2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KOS22377.1 - 3e-06 27.4 0.0 4.2e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KOS22377.1 - 0.0075 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Strep_his_triad PF04270.8 KOS22377.1 - 0.035 13.8 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Streptococcal histidine triad protein DNA_RNApol_7kD PF03604.8 KOS22378.1 - 5.4e-11 41.7 0.9 7.2e-11 41.3 0.6 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DnaJ_CXXCXGXG PF00684.14 KOS22378.1 - 0.00078 19.4 6.7 0.023 14.7 0.4 1.5 1 1 1 2 2 2 2 DnaJ central domain Zn-ribbon_8 PF09723.5 KOS22378.1 - 0.0035 17.2 1.0 0.0086 16.0 0.7 1.6 1 1 0 1 1 1 1 Zinc ribbon domain zf-RING_3 PF14369.1 KOS22378.1 - 0.0036 17.2 0.7 0.0061 16.5 0.5 1.4 1 1 0 1 1 1 1 zinc-finger A2L_zn_ribbon PF08792.5 KOS22378.1 - 0.0043 16.4 0.6 0.0069 15.8 0.4 1.3 1 0 0 1 1 1 1 A2L zinc ribbon domain Prok-RING_1 PF14446.1 KOS22378.1 - 0.0072 16.0 0.6 0.01 15.5 0.4 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 HypA PF01155.14 KOS22378.1 - 0.0089 15.7 0.2 0.011 15.3 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family zf-UDP PF14569.1 KOS22378.1 - 0.023 14.4 0.1 0.031 14.0 0.1 1.2 1 0 0 1 1 1 0 Zinc-binding RING-finger PhnA_Zn_Ribbon PF08274.7 KOS22378.1 - 0.025 14.3 0.4 0.043 13.5 0.3 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon DZR PF12773.2 KOS22378.1 - 0.037 13.8 0.2 0.051 13.4 0.1 1.2 1 0 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 KOS22378.1 - 0.055 12.8 0.1 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding GFA PF04828.9 KOS22378.1 - 0.057 13.3 0.5 3.1 7.8 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme NMU PF02070.10 KOS22378.1 - 0.063 12.8 0.2 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Neuromedin U zf-C2HC5 PF06221.8 KOS22378.1 - 0.086 12.6 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Zn_Tnp_IS1595 PF12760.2 KOS22378.1 - 0.091 12.5 2.6 0.34 10.7 0.2 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF329 PF03884.9 KOS22378.1 - 0.094 12.2 0.4 2.6 7.6 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF329) NinF PF05810.7 KOS22378.1 - 0.096 12.4 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 NinF protein Lar_restr_allev PF14354.1 KOS22378.1 - 0.1 12.9 2.3 3 8.2 0.1 2.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF1272 PF06906.6 KOS22378.1 - 0.3 10.9 2.0 9.6 6.1 1.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Auto_anti-p27 PF06677.7 KOS22378.1 - 0.35 10.6 2.1 0.59 9.9 1.3 1.5 1 1 1 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ATP_bind_1 PF03029.12 KOS22379.1 - 1.6e-75 253.7 0.0 2.2e-75 253.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KOS22379.1 - 7.9e-05 22.1 0.0 0.003 17.0 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 KOS22379.1 - 8.3e-05 21.4 0.0 0.062 12.0 0.0 2.6 2 1 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 KOS22379.1 - 0.00013 21.8 0.0 0.00046 20.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KOS22379.1 - 0.00015 21.9 0.0 0.00056 20.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KOS22379.1 - 0.00041 20.8 0.0 0.56 10.7 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 KOS22379.1 - 0.00054 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KOS22379.1 - 0.00063 20.5 1.6 0.0045 17.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS22379.1 - 0.00072 19.4 0.7 0.003 17.4 0.0 2.4 3 1 0 3 3 2 1 AAA domain AAA_10 PF12846.2 KOS22379.1 - 0.0015 18.0 0.9 0.0037 16.7 0.6 1.9 1 1 0 1 1 1 1 AAA-like domain CbiA PF01656.18 KOS22379.1 - 0.0019 17.6 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain FeoB_N PF02421.13 KOS22379.1 - 0.0022 17.2 0.0 0.059 12.6 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B SRP54 PF00448.17 KOS22379.1 - 0.0036 16.7 0.0 0.037 13.4 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.7 KOS22379.1 - 0.0039 16.8 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain cobW PF02492.14 KOS22379.1 - 0.0051 16.2 0.0 0.063 12.7 0.0 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 KOS22379.1 - 0.012 14.4 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 KOS22379.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KOS22379.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PVL_ORF50 PF07768.6 KOS22379.1 - 0.02 14.8 1.7 0.051 13.5 1.1 1.6 1 0 0 1 1 1 0 PVL ORF-50-like family LRS4 PF10422.4 KOS22379.1 - 0.021 14.2 1.8 0.033 13.5 1.2 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 G-alpha PF00503.15 KOS22379.1 - 0.022 13.4 0.4 2 6.9 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit AAA_18 PF13238.1 KOS22379.1 - 0.03 14.6 6.7 0.18 12.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 KOS22379.1 - 0.039 13.7 0.3 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 Arf PF00025.16 KOS22379.1 - 0.044 13.0 0.0 2.5 7.3 0.0 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family DUF2346 PF09803.4 KOS22379.1 - 0.06 13.2 0.3 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) PduV-EutP PF10662.4 KOS22379.1 - 0.073 12.5 0.0 0.35 10.3 0.0 2.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 KOS22379.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KOS22379.1 - 0.076 12.0 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.13 KOS22379.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 1 0 Phosphoribulokinase / Uridine kinase family Daxx PF03344.10 KOS22379.1 - 0.12 10.8 12.1 0.17 10.3 8.4 1.1 1 0 0 1 1 1 0 Daxx Family AAA_19 PF13245.1 KOS22379.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Nop25 PF09805.4 KOS22379.1 - 0.42 10.6 9.8 0.68 9.9 6.8 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SDA1 PF05285.7 KOS22379.1 - 0.82 8.8 13.2 1.2 8.3 9.1 1.2 1 0 0 1 1 1 0 SDA1 ChAPs PF09295.5 KOS22380.1 - 5.5e-157 522.5 0.0 7e-157 522.2 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 KOS22380.1 - 1.4e-06 28.4 0.6 0.37 11.5 0.4 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KOS22380.1 - 7.1e-06 25.5 1.1 0.0057 16.4 0.8 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS22380.1 - 8e-06 25.2 1.1 0.13 12.1 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KOS22380.1 - 1.1e-05 24.9 1.2 0.03 13.9 0.1 3.0 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 KOS22380.1 - 2.8e-05 23.5 0.1 0.041 13.6 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KOS22380.1 - 0.00058 19.3 0.5 0.45 10.2 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KOS22380.1 - 0.0013 18.5 1.3 0.73 9.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KOS22380.1 - 0.011 15.6 0.5 6.3 6.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KOS22380.1 - 0.075 13.5 2.4 30 5.3 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KOS22380.1 - 0.078 13.1 0.2 6.8 6.9 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Nop52 PF05997.7 KOS22381.1 - 5.1e-40 137.2 0.0 3.4e-39 134.5 0.0 1.9 1 1 0 1 1 1 1 Nucleolar protein,Nop52 Nucleoplasmin PF03066.10 KOS22381.1 - 0.5 9.8 6.0 0.78 9.2 4.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 KOS22381.1 - 1.8 7.1 10.3 2.5 6.7 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) UQ_con PF00179.21 KOS22382.1 - 6.6e-37 126.0 0.0 7.5e-37 125.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS22382.1 - 3.8e-05 23.4 0.0 4.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KOS22382.1 - 0.11 12.2 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 KOS22382.1 - 0.15 11.9 0.1 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain RabGAP-TBC PF00566.13 KOS22383.1 - 1.9e-37 128.8 0.0 1.9e-19 70.0 0.0 4.1 4 0 0 4 4 4 3 Rab-GTPase-TBC domain NOA36 PF06524.7 KOS22383.1 - 1.4 8.0 4.1 2.9 7.0 2.8 1.4 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 KOS22383.1 - 9.3 5.7 7.6 40 3.6 5.7 1.7 2 0 0 2 2 2 0 Nucleoplasmin TPR_11 PF13414.1 KOS22385.1 - 4.1e-06 26.3 13.5 0.018 14.6 0.2 4.9 5 0 0 5 5 5 3 TPR repeat TPR_17 PF13431.1 KOS22385.1 - 0.0011 18.9 1.9 1.5 9.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS22385.1 - 0.0061 16.8 3.5 0.32 11.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat VIT1 PF01988.14 KOS22385.1 - 0.028 13.8 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 VIT family TPR_14 PF13428.1 KOS22385.1 - 5 8.0 8.1 14 6.6 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.24 KOS22386.1 - 2.9e-46 157.0 0.0 4.3e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS22386.1 - 9.8e-26 89.4 0.0 2e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS22386.1 - 0.001 18.9 0.0 0.011 15.5 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit BTB PF00651.26 KOS22387.1 - 6e-07 29.4 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Lyase_8 PF02278.13 KOS22388.1 - 1.7e-29 103.0 0.1 2.7e-29 102.3 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 KOS22388.1 - 5.9e-12 45.0 0.0 9.6e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Amidase PF01425.16 KOS22389.1 - 1.9e-58 198.4 1.6 1.9e-49 168.6 1.3 2.2 1 1 1 2 2 2 2 Amidase NAD_binding_10 PF13460.1 KOS22390.1 - 2.2e-06 27.7 0.1 8.2e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KOS22390.1 - 0.00062 18.7 0.0 0.003 16.5 0.0 1.9 1 1 0 2 2 2 1 Male sterility protein DapB_N PF01113.15 KOS22390.1 - 0.011 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 KOS22390.1 - 0.014 14.2 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 KOS22390.1 - 0.016 15.1 0.1 0.036 13.9 0.1 1.7 1 1 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.16 KOS22390.1 - 0.024 14.0 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KOS22390.1 - 0.035 13.1 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF904 PF06005.7 KOS22391.1 - 0.068 13.4 0.6 0.068 13.4 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Spore_coat_CotO PF14153.1 KOS22391.1 - 0.14 11.5 12.4 0.079 12.3 4.0 2.2 2 0 0 2 2 2 0 Spore coat protein CotO DUF2897 PF11446.3 KOS22391.1 - 0.91 9.4 6.1 2.3 8.0 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) OmpH PF03938.9 KOS22391.1 - 1.8 8.4 30.6 3.6 7.4 9.4 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) vMSA PF00695.14 KOS22391.1 - 2 7.5 8.6 3.1 6.8 6.0 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus PBP1_TM PF14812.1 KOS22391.1 - 4.7 7.5 7.1 15 5.9 2.6 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Neur_chan_memb PF02932.11 KOS22391.1 - 5.5 6.8 7.5 8 6.2 4.9 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.5 KOS22391.1 - 7.5 4.6 42.1 10 4.1 29.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4557 PF15101.1 KOS22391.1 - 7.5 6.3 18.7 0.44 10.3 6.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) CTP_transf_1 PF01148.15 KOS22392.1 - 3.1e-80 269.5 31.7 3.8e-80 269.2 22.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Stanniocalcin PF03298.8 KOS22393.1 - 0.28 10.1 1.6 0.57 9.1 0.0 2.1 2 1 0 2 2 2 0 Stanniocalcin family NUDE_C PF04880.8 KOS22393.1 - 0.57 10.5 4.8 1.1 9.6 3.4 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF3636 PF12331.3 KOS22394.1 - 1e-26 93.2 0.0 1.9e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Thiolase_N PF00108.18 KOS22395.1 - 2.8e-70 236.3 0.2 4.8e-70 235.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KOS22395.1 - 1.2e-40 137.7 0.2 3.3e-40 136.3 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain Sulfate_transp PF00916.15 KOS22396.1 - 1e-52 178.9 3.7 1e-52 178.9 2.6 1.6 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KOS22396.1 - 4e-28 96.8 3.1 4e-28 96.8 2.2 2.2 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KOS22396.1 - 1.3e-16 60.0 0.0 2.6e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KOS22396.1 - 0.1 12.6 0.0 0.29 11.1 0.0 1.8 1 1 0 1 1 1 0 STAS domain Spt20 PF12090.3 KOS22397.1 - 1.8e-44 151.2 0.0 1.8e-44 151.2 0.0 6.5 3 1 1 4 4 4 1 Spt20 family Aminotran_3 PF00202.16 KOS22399.1 - 4.5e-91 305.2 0.0 5.4e-91 304.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III ATG27 PF09451.5 KOS22400.1 - 3.2e-75 252.8 0.0 4.1e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 KOS22400.1 - 0.00013 21.7 0.1 0.026 14.2 0.0 3.0 3 0 0 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat LRR_6 PF13516.1 KOS22401.1 - 0.00058 19.6 0.3 0.57 10.4 0.1 3.1 2 0 0 2 2 2 2 Leucine Rich repeat LRR_4 PF12799.2 KOS22401.1 - 0.0077 15.8 0.5 1.2 8.8 0.0 3.1 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KOS22401.1 - 0.03 14.3 6.2 0.7 10.1 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 KOS22401.1 - 0.072 13.3 3.7 1.9 9.0 0.0 4.0 4 0 0 4 4 4 0 Leucine rich repeat F-box PF00646.28 KOS22402.1 - 0.0014 18.1 0.3 0.004 16.7 0.2 1.7 1 0 0 1 1 1 1 F-box domain Hexapep PF00132.19 KOS22403.1 - 6.6e-12 44.3 0.5 6.2e-05 22.3 0.1 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KOS22403.1 - 5.2e-05 23.3 0.0 9.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KOS22403.1 - 0.025 14.1 12.3 0.54 9.8 0.3 3.7 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 KOS22403.1 - 0.027 13.7 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase Pet191_N PF10203.4 KOS22403.1 - 0.83 9.7 4.4 4.1 7.5 0.6 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 zf-C2H2 PF00096.21 KOS22404.1 - 1.8e-06 27.9 16.0 0.0066 16.7 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS22404.1 - 0.00021 21.3 13.3 0.12 12.7 4.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KOS22404.1 - 0.0064 16.7 2.0 0.0064 16.7 1.4 3.5 3 0 0 3 3 3 1 Zinc-finger double domain RdRP PF05183.7 KOS22405.1 - 9.5e-159 529.7 0.6 2.5e-82 277.4 0.1 2.1 2 0 0 2 2 2 2 RNA dependent RNA polymerase Abhydrolase_6 PF12697.2 KOS22406.1 - 1e-25 90.9 4.8 1e-25 90.9 3.3 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS22406.1 - 6.7e-09 35.6 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS22406.1 - 2.4e-05 24.1 0.0 7.8e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 KOS22406.1 - 0.0019 17.6 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KOS22406.1 - 0.041 13.0 0.0 4.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family RRM_1 PF00076.17 KOS22407.1 - 7.6e-09 35.0 0.0 3.7e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS22407.1 - 8.1e-09 35.3 0.0 2.5e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS22407.1 - 0.009 15.8 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CMS1 PF14617.1 KOS22408.1 - 7.6e-82 274.1 0.9 8.4e-82 274.0 0.6 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 KOS22408.1 - 1.3e-06 28.0 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase HpaP PF09483.5 KOS22408.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Type III secretion protein (HpaP) SH3_1 PF00018.23 KOS22409.1 - 9.5e-17 60.1 0.0 1.8e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KOS22409.1 - 1.7e-12 46.5 0.0 2.7e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KOS22409.1 - 1.9e-11 43.3 0.0 3e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2360 PF10152.4 KOS22409.1 - 0.48 10.7 11.1 0.059 13.6 1.6 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) BAT2_N PF07001.6 KOS22409.1 - 4.3 7.6 13.3 1.3 9.3 0.8 2.2 2 0 0 2 2 2 0 BAT2 N-terminus MmgE_PrpD PF03972.9 KOS22410.1 - 4.9e-147 489.6 0.0 5.9e-147 489.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DNA_photolyase PF00875.13 KOS22411.1 - 3e-15 56.3 0.0 4.1e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.9 KOS22412.1 - 5.6e-58 196.3 0.1 6.8e-58 196.0 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase MFS_1 PF07690.11 KOS22413.1 - 1.1e-26 93.4 36.3 2.8e-13 49.3 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KOS22413.1 - 1.2e-05 23.8 22.2 0.0015 17.0 2.7 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 KOS22413.1 - 0.0084 14.7 11.7 0.0046 15.5 2.2 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KOS22413.1 - 0.043 13.5 8.1 0.076 12.8 0.4 3.5 3 1 0 3 3 3 0 MFS_1 like family Methyltransf_11 PF08241.7 KOS22414.1 - 4.1e-31 107.3 0.0 5.8e-15 55.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KOS22414.1 - 3.6e-25 88.5 0.0 3.3e-15 56.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KOS22414.1 - 2.3e-23 82.9 0.0 5.3e-12 46.3 0.0 2.8 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 KOS22414.1 - 1.9e-22 79.4 0.0 6e-12 45.3 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 KOS22414.1 - 2.5e-17 63.0 0.0 2.9e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KOS22414.1 - 5.4e-17 62.0 0.0 1e-09 38.7 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain MetW PF07021.7 KOS22414.1 - 2.2e-12 46.7 0.0 3.5e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 KOS22414.1 - 6.7e-12 45.0 0.0 1.9e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KOS22414.1 - 1.8e-11 44.1 0.2 4.3e-05 23.5 0.0 3.2 3 1 0 3 3 3 2 Methyltransferase domain CMAS PF02353.15 KOS22414.1 - 6e-09 35.3 0.0 1.1e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 KOS22414.1 - 5e-07 29.0 0.0 2.6e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Tellurite resistance protein TehB PCMT PF01135.14 KOS22414.1 - 8.4e-07 28.7 0.0 0.0095 15.4 0.0 2.3 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.6 KOS22414.1 - 1.9e-06 27.3 0.0 0.00024 20.5 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.9 KOS22414.1 - 3.9e-06 26.3 0.0 0.0095 15.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain DREV PF05219.7 KOS22414.1 - 2.5e-05 23.2 0.0 0.043 12.7 0.0 2.6 3 0 0 3 3 3 2 DREV methyltransferase RrnaAD PF00398.15 KOS22414.1 - 5.6e-05 22.2 0.0 0.28 10.1 0.0 2.3 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase GidB PF02527.10 KOS22414.1 - 0.00014 21.0 0.1 0.088 11.9 0.0 2.2 2 0 0 2 2 2 2 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.12 KOS22414.1 - 0.00049 19.2 0.0 0.64 9.0 0.0 2.5 3 0 0 3 3 3 2 Putative methyltransferase Methyltransf_32 PF13679.1 KOS22414.1 - 0.00094 18.8 0.0 0.28 10.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.7 KOS22414.1 - 0.0011 18.5 0.0 0.81 9.1 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF938) Methyltransf_15 PF09445.5 KOS22414.1 - 0.0016 18.0 0.0 0.0051 16.3 0.0 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 KOS22414.1 - 0.002 17.3 0.0 0.088 11.9 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.6 KOS22414.1 - 0.0028 17.1 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) UDPG_MGDP_dh_N PF03721.9 KOS22414.1 - 0.016 14.5 0.0 0.041 13.2 0.0 1.6 2 0 0 2 2 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FmrO PF07091.6 KOS22414.1 - 0.063 12.2 0.0 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) CheR PF01739.13 KOS22414.1 - 0.088 12.0 0.0 7.2 5.8 0.0 2.8 2 1 1 3 3 3 0 CheR methyltransferase, SAM binding domain TetR_N PF00440.18 KOS22414.1 - 0.09 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family FtsJ PF01728.14 KOS22414.1 - 0.16 11.9 0.0 0.91 9.4 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase Amidase PF01425.16 KOS22415.1 - 9.6e-48 163.1 6.3 8.3e-47 160.0 1.7 2.8 2 1 0 2 2 2 2 Amidase Mob1_phocein PF03637.12 KOS22416.1 - 5.2e-35 120.6 0.5 2.3e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 Mob1/phocein family Med3 PF11593.3 KOS22416.1 - 0.46 9.6 2.1 0.68 9.1 1.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ank_2 PF12796.2 KOS22417.1 - 4.1e-20 71.9 0.0 5.3e-09 36.3 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KOS22417.1 - 3.9e-19 67.4 3.9 5.7e-05 22.7 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KOS22417.1 - 1.7e-15 56.6 1.6 3.7e-06 27.0 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeats (many copies) ArsB PF02040.10 KOS22417.1 - 6.5e-14 51.7 13.3 1e-10 41.2 4.7 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein Ank_3 PF13606.1 KOS22417.1 - 4.2e-13 48.1 0.4 0.0012 18.8 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KOS22417.1 - 3e-12 46.7 3.2 2.9e-07 30.8 0.1 4.7 4 1 1 5 5 5 2 Ankyrin repeats (many copies) FA_hydroxylase PF04116.8 KOS22418.1 - 8.3e-05 22.9 6.6 8.3e-05 22.9 4.6 2.7 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily DSS1_SEM1 PF05160.8 KOS22419.1 - 9.3e-23 79.7 14.9 9.3e-23 79.7 10.3 1.5 1 1 1 2 2 2 1 DSS1/SEM1 family DUF3808 PF10300.4 KOS22420.1 - 7e-125 417.2 0.0 9.6e-125 416.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.1 KOS22420.1 - 0.0097 16.5 2.5 9.5 7.0 0.1 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KOS22420.1 - 0.03 14.6 3.6 2 8.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MSA-2c PF12238.3 KOS22420.1 - 0.08 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c TPR_12 PF13424.1 KOS22420.1 - 6.7 6.7 7.6 11 5.9 0.0 4.0 4 2 0 4 4 4 0 Tetratricopeptide repeat Mpv17_PMP22 PF04117.7 KOS22421.1 - 7.8e-24 83.1 0.3 2e-23 81.7 0.2 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family PGK PF00162.14 KOS22422.1 - 3e-152 506.6 1.0 3.4e-152 506.4 0.7 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.6 KOS22422.1 - 0.0028 17.0 0.6 1.2 8.4 0.1 3.5 4 0 0 4 4 4 2 Propionate catabolism activator Kinesin PF00225.18 KOS22423.1 - 2.9e-56 190.6 0.0 9.9e-56 188.8 0.0 1.9 1 1 0 1 1 1 1 Kinesin motor domain DivIC PF04977.10 KOS22423.1 - 0.07 12.6 8.6 0.089 12.2 2.4 2.8 2 0 0 2 2 2 0 Septum formation initiator DUF1192 PF06698.6 KOS22423.1 - 0.083 12.7 13.4 0.2 11.5 4.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Peptidase_S24 PF00717.18 KOS22425.1 - 2.3e-08 33.5 0.1 3.3e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like Tad PF13400.1 KOS22426.1 - 0.47 10.5 8.2 0.38 10.8 1.7 2.6 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Spindle_Spc25 PF08234.7 KOS22427.1 - 5.6e-22 77.5 0.2 1.6e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Atg14 PF10186.4 KOS22427.1 - 0.033 13.1 7.4 0.048 12.6 5.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 KOS22427.1 - 0.044 12.2 2.4 0.053 11.9 1.7 1.2 1 0 0 1 1 1 0 AAA domain CDC37_N PF03234.9 KOS22427.1 - 0.094 13.0 2.2 0.16 12.2 1.5 1.5 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding AAA_23 PF13476.1 KOS22427.1 - 0.15 12.3 2.7 0.21 11.8 1.9 1.2 1 0 0 1 1 1 0 AAA domain THOC7 PF05615.8 KOS22427.1 - 0.15 12.3 8.2 0.049 13.8 3.8 1.6 2 0 0 2 2 2 0 Tho complex subunit 7 APG6 PF04111.7 KOS22427.1 - 0.21 10.5 8.7 0.16 10.9 0.8 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Peptidase_S46 PF10459.4 KOS22427.1 - 0.52 8.6 5.8 0.69 8.2 4.0 1.1 1 0 0 1 1 1 0 Peptidase S46 Mnd1 PF03962.10 KOS22427.1 - 1.2 8.8 12.8 5.7 6.5 6.1 2.3 1 1 1 2 2 2 0 Mnd1 family DegS PF05384.6 KOS22427.1 - 3.5 6.8 13.3 0.5 9.5 5.3 2.3 2 1 0 3 3 3 0 Sensor protein DegS Rrn6 PF10214.4 KOS22428.1 - 4.1e-40 137.6 0.0 1.2e-32 112.9 0.0 2.2 2 1 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor zinc_ribbon_6 PF14599.1 KOS22429.1 - 3.4e-25 87.5 0.8 3.4e-25 87.5 0.5 3.7 4 1 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 KOS22429.1 - 4.2e-17 62.0 20.7 4.2e-17 62.0 14.3 4.0 2 1 2 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 KOS22429.1 - 2.7e-09 36.7 9.7 2.7e-09 36.7 6.7 5.1 4 1 1 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.1 KOS22429.1 - 1.2e-08 34.8 7.9 1.2e-08 34.8 5.5 5.6 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS22429.1 - 2.8e-08 33.3 7.0 2.8e-08 33.3 4.9 5.7 2 1 4 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS22429.1 - 2e-05 24.1 4.9 2e-05 24.1 3.4 5.1 2 2 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS22429.1 - 4e-05 23.2 7.8 4e-05 23.2 5.4 6.4 2 1 3 5 5 5 1 zinc-RING finger domain Nop14 PF04147.7 KOS22429.1 - 2.2 6.1 27.0 3 5.6 18.7 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 KOS22429.1 - 4.3 6.9 18.1 9.7 5.7 12.6 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region ANAPC15 PF15243.1 KOS22429.1 - 5.1 7.2 20.3 16 5.6 14.1 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 MOZART1 PF12554.3 KOS22430.1 - 3e-25 87.4 1.0 3.6e-25 87.1 0.7 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.2 KOS22430.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Coa1 PF08695.5 KOS22431.1 - 1.7e-40 137.1 0.0 2.2e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 PITH PF06201.8 KOS22433.1 - 1.8e-41 141.4 0.0 2.2e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain Ribosomal_L3 PF00297.17 KOS22434.1 - 1.3e-33 116.5 1.8 6.1e-33 114.3 1.2 1.9 1 1 0 1 1 1 1 Ribosomal protein L3 SPX PF03105.14 KOS22435.1 - 3e-29 102.6 13.8 5.3e-15 55.9 4.2 2.6 2 1 1 3 3 3 2 SPX domain Ank_5 PF13857.1 KOS22435.1 - 1.2e-10 41.2 2.1 0.00015 21.8 0.0 3.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KOS22435.1 - 2.4e-09 37.4 1.1 6.6e-08 32.7 0.1 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KOS22435.1 - 3.3e-09 36.9 2.2 8.1e-08 32.5 0.1 3.6 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 KOS22435.1 - 2.6e-07 30.1 0.7 0.0035 17.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KOS22435.1 - 0.00016 21.6 1.0 0.82 10.1 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat CUE PF02845.11 KOS22436.1 - 2.2e-13 49.4 0.0 3.9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain Complex1_LYR PF05347.10 KOS22437.1 - 4.3e-07 29.6 0.0 8.7e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KOS22437.1 - 1.3e-05 25.3 0.0 2.7e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Complex1_LYR-like zf-C4H2 PF10146.4 KOS22438.1 - 3.3 7.6 6.5 1.7 8.6 0.2 2.7 2 1 0 2 2 2 0 Zinc finger-containing protein DUF3437 PF11919.3 KOS22439.1 - 1.8e-31 107.6 0.0 4.7e-31 106.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 KOS22439.1 - 0.00025 20.8 0.0 5.5 7.3 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat A_deaminase PF00962.17 KOS22440.1 - 8.4e-39 133.3 0.0 8.2e-37 126.8 0.0 2.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase Chalcone PF02431.10 KOS22441.1 - 4.3e-60 202.5 0.0 5.3e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Melibiase PF02065.13 KOS22442.1 - 4.4e-146 486.5 0.0 5.4e-146 486.3 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 KOS22442.1 - 0.00022 20.1 0.0 0.00035 19.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 F-box-like PF12937.2 KOS22443.1 - 1.6e-13 50.1 2.8 2.3e-13 49.6 0.5 2.5 3 0 0 3 3 3 1 F-box-like LRR_6 PF13516.1 KOS22443.1 - 1.6e-12 46.1 21.9 0.93 9.7 0.0 11.4 12 0 0 12 12 12 5 Leucine Rich repeat LRR_1 PF00560.28 KOS22443.1 - 8.1e-07 28.2 24.7 6.4 7.2 0.0 10.2 8 2 0 8 8 8 2 Leucine Rich Repeat LRR_4 PF12799.2 KOS22443.1 - 1.5e-06 27.6 14.9 0.13 11.9 0.0 6.3 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) F-box PF00646.28 KOS22443.1 - 3.7e-06 26.4 2.2 1.1e-05 24.9 0.4 2.6 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 KOS22443.1 - 0.00035 20.2 21.7 0.22 11.3 0.3 5.7 2 1 4 7 7 7 6 Leucine rich repeat Recep_L_domain PF01030.19 KOS22443.1 - 0.2 11.6 4.2 26 4.8 0.1 3.9 3 1 0 4 4 4 0 Receptor L domain Pkinase PF00069.20 KOS22444.1 - 1.4e-29 103.0 0.0 1.4e-28 99.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS22444.1 - 6.6e-19 67.9 0.0 1.1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Nucleoplasmin PF03066.10 KOS22444.1 - 0.026 14.0 1.4 0.055 12.9 1.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin FUSC PF04632.7 KOS22444.1 - 0.044 12.2 0.3 0.076 11.4 0.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Myc_N PF01056.13 KOS22444.1 - 0.077 12.1 10.3 0.14 11.3 6.8 1.7 1 1 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 KOS22444.1 - 0.73 10.1 6.0 1.7 8.9 4.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 KOS22444.1 - 3.7 7.9 7.1 0.29 11.4 1.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SRP40_C PF05022.7 KOS22445.1 - 4e-22 78.5 0.5 9.3e-22 77.3 0.3 1.7 1 0 0 1 1 1 1 SRP40, C-terminal domain MIP-T3 PF10243.4 KOS22445.1 - 0.026 13.0 43.8 0.032 12.7 30.3 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 KOS22445.1 - 0.2 10.8 52.3 0.3 10.2 36.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Atrophin-1 PF03154.10 KOS22445.1 - 0.21 9.7 40.4 0.26 9.3 28.0 1.3 1 0 0 1 1 1 0 Atrophin-1 family FAM196 PF15265.1 KOS22445.1 - 6 5.9 32.8 6.8 5.8 22.7 1.1 1 0 0 1 1 1 0 FAM196 family zf-C3HC PF07967.8 KOS22446.1 - 4.2e-26 91.2 0.0 2.1e-21 76.0 0.1 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 KOS22446.1 - 5.7e-25 86.9 1.2 8.8e-24 83.1 0.0 2.4 2 0 0 2 2 2 1 Rsm1-like BIR PF00653.16 KOS22446.1 - 1e-05 25.8 0.2 0.00086 19.6 0.1 2.8 2 1 1 3 3 3 1 Inhibitor of Apoptosis domain EF1G PF00647.14 KOS22446.1 - 0.083 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain zf-BED PF02892.10 KOS22446.1 - 0.12 12.1 2.0 0.18 11.5 0.3 1.9 2 0 0 2 2 2 0 BED zinc finger APH PF01636.18 KOS22447.1 - 1.2e-11 44.8 1.8 2.3e-11 43.9 1.3 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family PTPLA PF04387.9 KOS22448.1 - 8.8e-49 165.0 9.0 1.9e-48 164.0 6.3 1.5 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Amidohydro_2 PF04909.9 KOS22449.1 - 7.4e-43 147.0 0.1 9.1e-43 146.7 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 KOS22449.1 - 0.06 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 TatD related DNase DIOX_N PF14226.1 KOS22450.1 - 2.3e-26 92.5 0.5 3.7e-26 91.9 0.1 1.5 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KOS22450.1 - 1.4e-18 67.0 0.0 2.7e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GCV_T PF01571.16 KOS22451.1 - 6.1e-15 55.1 0.1 2.5e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KOS22451.1 - 0.0064 16.4 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DnaJ PF00226.26 KOS22452.1 - 1.1e-12 47.5 3.2 3.2e-12 45.9 0.1 2.8 3 0 0 3 3 3 1 DnaJ domain BTV_NS2 PF04514.7 KOS22452.1 - 0.22 10.3 14.9 0.29 9.9 10.3 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Asp-B-Hydro_N PF05279.6 KOS22452.1 - 0.35 10.6 18.1 0.52 10.1 12.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region V_ATPase_I PF01496.14 KOS22452.1 - 3.1 5.5 7.3 4 5.1 5.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.6 KOS22452.1 - 3.5 5.8 23.6 4.7 5.3 16.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ycf1 PF05758.7 KOS22452.1 - 3.8 5.0 9.9 4.3 4.9 6.8 1.1 1 0 0 1 1 1 0 Ycf1 Pilt PF15453.1 KOS22452.1 - 4.8 6.7 15.3 6.7 6.2 10.6 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DUF4407 PF14362.1 KOS22452.1 - 5.1 5.9 14.3 6.7 5.5 9.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AA_permease_2 PF13520.1 KOS22454.1 - 8.3e-54 182.7 49.0 1.1e-53 182.3 34.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KOS22454.1 - 4.9e-17 61.4 40.0 6.8e-17 60.9 27.7 1.1 1 0 0 1 1 1 1 Amino acid permease Asparaginase_2 PF01112.13 KOS22455.1 - 6.7e-66 222.1 4.8 1.5e-65 221.0 3.5 1.3 2 0 0 2 2 2 1 Asparaginase CDC45 PF02724.9 KOS22456.1 - 0.33 8.9 5.3 0.44 8.5 3.6 1.2 1 0 0 1 1 1 0 CDC45-like protein AMP-binding PF00501.23 KOS22457.1 - 1.7e-65 221.0 0.0 2.2e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS22457.1 - 7.7e-10 39.5 0.8 7.7e-10 39.5 0.6 2.5 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain TPR_1 PF00515.23 KOS22458.1 - 1.4e-12 46.6 0.4 0.00056 19.4 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS22458.1 - 7.3e-12 44.2 8.2 0.0032 17.2 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KOS22458.1 - 1.9e-10 40.5 11.1 4.2e-05 23.4 0.5 5.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KOS22458.1 - 4.2e-10 38.6 5.3 0.0006 19.4 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KOS22458.1 - 4.6e-10 39.8 17.4 2.7e-06 27.9 0.3 6.3 5 2 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KOS22458.1 - 1.1e-09 37.8 5.4 7.2e-06 25.5 0.4 4.0 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 KOS22458.1 - 5.8e-07 29.7 14.8 0.00022 21.5 0.2 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS22458.1 - 1.8e-05 24.1 3.4 3.1 7.8 0.0 5.8 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.1 KOS22458.1 - 4.9e-05 23.3 1.3 0.00015 21.8 0.0 2.5 3 0 0 3 3 2 1 AAA ATPase domain TPR_6 PF13174.1 KOS22458.1 - 0.00012 22.2 6.1 0.015 15.6 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat AAA_22 PF13401.1 KOS22458.1 - 0.00017 21.7 0.0 0.001 19.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KOS22458.1 - 0.00019 21.1 0.0 0.00099 18.8 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_5 PF07728.9 KOS22458.1 - 0.00044 19.9 0.2 0.058 13.1 0.0 3.7 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) TPR_14 PF13428.1 KOS22458.1 - 0.0021 18.5 22.3 1.2 9.9 0.0 7.9 6 2 2 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KOS22458.1 - 0.0022 18.1 2.4 0.056 13.5 0.8 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 AAA_10 PF12846.2 KOS22458.1 - 0.0067 15.8 0.0 0.043 13.2 0.0 2.5 2 1 0 2 2 2 1 AAA-like domain TPR_17 PF13431.1 KOS22458.1 - 0.016 15.3 3.3 0.058 13.6 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat BTAD PF03704.12 KOS22458.1 - 0.051 13.8 9.1 4 7.7 0.8 4.0 3 0 0 3 3 3 0 Bacterial transcriptional activator domain RNA_helicase PF00910.17 KOS22458.1 - 0.062 13.4 0.0 0.23 11.6 0.0 2.0 2 0 0 2 2 1 0 RNA helicase TPR_10 PF13374.1 KOS22458.1 - 0.11 12.5 7.4 21 5.1 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 KOS22458.1 - 0.2 11.7 4.6 0.12 12.4 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF4066 PF13278.1 KOS22459.1 - 2.5e-34 117.9 0.0 2.9e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KOS22459.1 - 7.5e-13 48.1 0.0 1e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family MFS_1 PF07690.11 KOS22462.1 - 6e-10 38.3 51.4 1.7e-09 36.9 34.3 2.7 2 1 1 3 3 3 1 Major Facilitator Superfamily FUN14 PF04930.10 KOS22462.1 - 0.18 12.0 2.7 0.63 10.3 1.9 1.9 1 0 0 1 1 1 0 FUN14 family Mito_carr PF00153.22 KOS22463.1 - 1e-57 191.8 4.5 1.7e-22 78.9 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein COX6C PF02937.10 KOS22464.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc DUF2370 PF10176.4 KOS22465.1 - 6.4e-84 280.9 0.0 1e-83 280.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) PCMT PF01135.14 KOS22466.1 - 5.3e-42 143.7 0.0 7.1e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KOS22466.1 - 6.2e-06 25.8 0.0 8.4e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS22466.1 - 0.00017 22.1 0.0 0.00024 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS22466.1 - 0.00059 19.8 0.0 0.00093 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KOS22466.1 - 0.0014 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS22466.1 - 0.0047 16.6 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KOS22466.1 - 0.012 14.7 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.12 KOS22466.1 - 0.031 13.3 0.0 0.055 12.5 0.0 1.4 2 0 0 2 2 2 0 O-methyltransferase RrnaAD PF00398.15 KOS22466.1 - 0.053 12.5 0.0 0.08 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 KOS22466.1 - 0.091 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.5 KOS22466.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Exo_endo_phos PF03372.18 KOS22467.1 - 1.3e-14 54.7 0.8 2.3e-14 53.9 0.5 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KOS22467.1 - 0.022 14.3 0.0 0.11 12.1 0.0 2.1 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DPPIV_N PF00930.16 KOS22468.1 - 5e-103 344.3 0.9 8.7e-103 343.5 0.7 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KOS22468.1 - 3.2e-37 127.8 0.8 5.8e-37 126.9 0.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KOS22468.1 - 3.1e-07 30.2 0.0 7.5e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS22468.1 - 0.00011 22.1 0.3 0.00035 20.5 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Bac_chlorC PF02043.12 KOS22469.1 - 0.0098 15.6 1.2 0.019 14.7 0.8 1.5 1 0 0 1 1 1 1 Bacteriochlorophyll C binding protein Cerato-platanin PF07249.7 KOS22469.1 - 0.095 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Cerato-platanin Cu-oxidase_3 PF07732.10 KOS22470.1 - 2.1e-41 140.3 0.4 7.6e-39 132.0 0.1 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KOS22470.1 - 6.9e-31 106.5 6.6 4e-29 100.8 0.3 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 KOS22470.1 - 1.4e-13 51.0 0.0 6.2e-12 45.7 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Phosphoesterase PF04185.9 KOS22471.1 - 6.7e-56 190.1 4.6 9.2e-56 189.6 3.2 1.1 1 0 0 1 1 1 1 Phosphoesterase family SPC12 PF06645.8 KOS22472.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Acetyltransf_1 PF00583.19 KOS22473.1 - 1.6e-07 31.2 0.0 2.4e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS22473.1 - 0.0002 21.4 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS22473.1 - 0.00084 19.4 0.0 0.0025 17.9 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KOS22473.1 - 0.0059 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 KOS22473.1 - 0.02 14.7 0.0 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CENP-L PF13092.1 KOS22474.1 - 3.6e-44 150.4 0.0 4.4e-43 146.8 0.0 2.0 2 0 0 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 NAD_binding_10 PF13460.1 KOS22475.1 - 4.2e-09 36.6 0.0 5e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 KOS22475.1 - 1.2e-05 25.2 0.1 4.2e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 KOS22475.1 - 1.5e-05 24.0 0.0 0.00076 18.4 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 KOS22475.1 - 2.4e-05 23.2 0.1 3.4e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KOS22475.1 - 9.5e-05 21.9 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KOS22475.1 - 0.00035 19.9 0.0 0.00044 19.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 KOS22475.1 - 0.0008 18.3 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KOS22475.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KOS22475.1 - 0.035 13.0 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Semialdhyde_dh PF01118.19 KOS22475.1 - 0.038 14.2 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KOS22475.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 KR domain Glyco_hydro_16 PF00722.16 KOS22476.1 - 6.7e-17 61.3 0.0 1e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 KOS22476.1 - 0.0004 18.6 0.8 0.0041 15.3 0.1 2.0 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF89 PF01937.14 KOS22477.1 - 1.3e-113 379.4 0.0 1.6e-113 379.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Sugar_tr PF00083.19 KOS22479.1 - 6.3e-109 364.5 17.1 7.6e-109 364.2 11.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS22479.1 - 8.2e-31 106.9 42.0 9.3e-29 100.2 10.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KOS22479.1 - 1.8e-05 23.3 8.1 0.0005 18.5 0.2 3.0 4 0 0 4 4 4 2 MFS/sugar transport protein TRI12 PF06609.8 KOS22479.1 - 9.9e-05 20.7 0.3 0.00019 19.7 0.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MUG113 PF13455.1 KOS22480.1 - 3.3e-25 88.3 0.1 6.2e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KOS22480.1 - 1.8e-17 63.5 0.0 3.8e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain RAI16-like PF10257.4 KOS22481.1 - 2.2e-58 197.9 0.6 3.4e-58 197.2 0.4 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF1700 PF08006.6 KOS22483.1 - 0.3 10.3 3.1 0.4 9.9 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Clc-like PF07062.7 KOS22483.1 - 1.5 8.0 5.2 1.9 7.6 3.6 1.2 1 0 0 1 1 1 0 Clc-like IncA PF04156.9 KOS22483.1 - 7.7 6.0 16.2 2.9 7.4 9.2 1.7 1 1 0 1 1 1 0 IncA protein S1-P1_nuclease PF02265.11 KOS22484.1 - 2.7e-69 233.5 0.0 3.2e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease DUF4535 PF15054.1 KOS22484.1 - 0.027 13.8 0.4 0.091 12.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) UQ_con PF00179.21 KOS22485.1 - 8.4e-38 128.9 0.0 1e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS22485.1 - 3e-06 26.9 0.0 4.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_3 PF09288.5 KOS22485.1 - 4.2e-05 23.0 0.1 7.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain RWD PF05773.17 KOS22485.1 - 0.083 12.7 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain AAA PF00004.24 KOS22486.1 - 1.5e-41 141.7 0.0 2.8e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS22486.1 - 1.2e-06 28.7 0.1 0.00031 20.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KOS22486.1 - 3.5e-06 27.0 0.0 7.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KOS22486.1 - 1.3e-05 24.2 0.0 2.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KOS22486.1 - 3.1e-05 23.7 0.1 0.00013 21.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KOS22486.1 - 0.00027 20.9 0.5 0.0016 18.4 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KOS22486.1 - 0.00046 19.2 0.0 0.00085 18.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KOS22486.1 - 0.001 19.0 0.4 0.0046 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KOS22486.1 - 0.0038 17.1 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS22486.1 - 0.0054 17.5 0.7 0.012 16.3 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KOS22486.1 - 0.0059 16.3 0.3 0.015 15.0 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KOS22486.1 - 0.0064 15.9 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KOS22486.1 - 0.0083 15.9 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS22486.1 - 0.0088 15.1 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KOS22486.1 - 0.011 16.0 0.1 0.024 14.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KOS22486.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KOS22486.1 - 0.013 15.1 0.2 0.32 10.6 0.0 2.6 2 1 1 3 3 3 0 NACHT domain TIP49 PF06068.8 KOS22486.1 - 0.021 13.5 0.0 0.041 12.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus NB-ARC PF00931.17 KOS22486.1 - 0.034 13.0 0.0 0.059 12.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 KOS22486.1 - 0.041 13.4 0.2 0.13 11.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KOS22486.1 - 0.044 13.9 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 KOS22486.1 - 0.05 12.7 0.1 0.099 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KOS22486.1 - 0.058 12.4 0.1 0.4 9.7 0.0 2.2 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 KOS22486.1 - 0.064 12.4 2.2 0.2 10.8 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 KOS22486.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 KOS22486.1 - 0.18 12.1 0.5 0.82 9.9 0.3 2.3 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 KOS22486.1 - 0.25 10.7 6.0 0.25 10.7 0.3 2.8 2 1 0 3 3 3 0 AAA domain RTC4 PF14474.1 KOS22487.1 - 1.5e-26 92.7 0.0 3.1e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain Dynamitin PF04912.9 KOS22488.1 - 1.3e-26 93.3 1.9 9.9e-21 73.9 0.0 3.0 2 1 0 2 2 2 2 Dynamitin DUF3450 PF11932.3 KOS22488.1 - 0.00025 20.3 0.9 0.16 11.2 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) Laminin_II PF06009.7 KOS22488.1 - 0.0086 15.8 4.5 0.13 12.0 0.0 3.6 2 1 1 3 3 3 1 Laminin Domain II FH2 PF02181.18 KOS22488.1 - 0.0087 14.9 0.5 0.79 8.5 0.0 2.6 3 0 0 3 3 3 1 Formin Homology 2 Domain BLOC1_2 PF10046.4 KOS22488.1 - 0.075 13.1 2.8 4.1 7.6 0.0 3.7 2 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 KOS22488.1 - 0.23 10.9 9.6 2.8 7.4 0.1 3.4 3 0 0 3 3 3 0 Septum formation initiator TPR_MLP1_2 PF07926.7 KOS22488.1 - 0.36 10.5 6.6 7.3 6.3 0.1 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 KOS22488.1 - 0.44 10.4 8.2 3.1 7.7 0.0 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding COG2 PF06148.6 KOS22488.1 - 1.6 8.6 4.0 5.1 6.9 0.2 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_GP20 PF06810.6 KOS22488.1 - 3.3 7.1 6.9 7.2 6.0 0.1 2.9 3 0 0 3 3 3 0 Phage minor structural protein GP20 HWE_HK PF07536.9 KOS22488.1 - 4.6 7.7 7.1 0.67 10.4 0.9 2.6 3 0 0 3 3 3 0 HWE histidine kinase CBS PF00571.23 KOS22489.1 - 0.0097 15.6 0.0 2 8.2 0.0 2.9 2 1 0 2 2 2 2 CBS domain Mito_carr PF00153.22 KOS22490.1 - 9e-52 172.7 8.0 8.8e-20 70.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Epimerase PF01370.16 KOS22491.1 - 7.6e-21 74.6 0.0 1.1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KOS22491.1 - 5.7e-10 38.5 0.0 1e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KOS22491.1 - 1.4e-07 31.5 0.0 7.4e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KOS22491.1 - 4.5e-06 26.7 0.0 1.7e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KOS22491.1 - 6.9e-06 25.1 0.0 1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KOS22491.1 - 0.00058 18.6 0.0 0.00097 17.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KOS22491.1 - 0.0073 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 KOS22491.1 - 0.098 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain LRR_4 PF12799.2 KOS22493.1 - 2.1e-54 180.3 59.8 6e-08 32.1 0.9 13.2 8 4 6 14 14 14 10 Leucine Rich repeats (2 copies) PP2C PF00481.16 KOS22493.1 - 2.2e-52 177.9 0.0 3.6e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 KOS22493.1 - 4.9e-43 144.7 62.6 4.3e-10 39.1 1.5 9.8 6 3 6 12 12 12 10 Leucine rich repeat Guanylate_cyc PF00211.15 KOS22493.1 - 6.6e-32 110.3 0.0 1.3e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KOS22493.1 - 4.7e-31 102.0 52.4 0.14 12.2 0.0 20.0 19 1 1 20 20 20 11 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 KOS22493.1 - 4.6e-17 61.0 2.2 1.2e-16 59.7 1.5 1.7 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_7 PF13504.1 KOS22493.1 - 7.1e-17 58.5 56.6 0.37 11.1 0.1 18.9 20 0 0 20 20 20 6 Leucine rich repeat RA PF00788.18 KOS22493.1 - 4.1e-09 36.7 0.0 8.9e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 KOS22493.1 - 6.6e-06 25.6 52.9 4.3 7.7 0.2 16.4 18 0 0 18 18 18 1 Leucine Rich repeat LRR_9 PF14580.1 KOS22493.1 - 0.0048 16.4 8.9 1.2 8.6 0.3 4.0 4 1 0 4 4 4 2 Leucine-rich repeat Alpha-amylase PF00128.19 KOS22494.1 - 1.7e-103 346.3 0.1 2.8e-103 345.6 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KOS22494.1 - 0.031 13.2 0.0 0.059 12.2 0.0 1.4 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Alpha-amylase_C PF02806.13 KOS22494.1 - 0.033 14.3 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain UCH PF00443.24 KOS22495.1 - 5.9e-62 209.2 0.0 1.1e-61 208.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS22495.1 - 3e-29 102.4 0.2 1.1e-22 80.7 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KOS22495.1 - 0.68 9.1 4.9 2.1 7.5 0.7 2.8 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Glyco_transf_22 PF03901.12 KOS22496.1 - 1.7e-41 142.6 9.6 2.2e-41 142.2 6.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PAT1 PF09770.4 KOS22497.1 - 2.2 6.4 19.1 2.5 6.2 13.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SIT PF15330.1 KOS22497.1 - 3.3 7.8 9.8 9.8 6.3 6.8 1.8 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF3336 PF11815.3 KOS22498.1 - 2.3e-38 130.9 0.4 4e-38 130.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KOS22498.1 - 1.4e-23 83.9 0.0 3.2e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase AMP-binding PF00501.23 KOS22499.1 - 2e-66 224.1 0.0 3.2e-66 223.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS22499.1 - 4.1e-07 30.8 0.0 1.1e-06 29.4 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain PIG-S PF10510.4 KOS22500.1 - 3.8e-146 487.7 0.0 4.4e-146 487.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein AhpC-TSA PF00578.16 KOS22501.1 - 5.7e-32 110.0 0.0 8.4e-32 109.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 KOS22501.1 - 7.6e-13 47.8 0.1 1.3e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 KOS22501.1 - 3.9e-11 42.6 0.0 4.6e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin Kelch_6 PF13964.1 KOS22502.1 - 0.00027 20.9 0.5 1.9 8.7 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 KOS22502.1 - 0.00036 20.6 4.5 0.029 14.5 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.1 KOS22502.1 - 0.00085 19.0 6.0 0.017 14.9 0.0 4.3 5 0 0 5 5 5 1 Galactose oxidase, central domain BTB PF00651.26 KOS22502.1 - 0.0018 18.2 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.10 KOS22502.1 - 0.012 15.4 0.1 4.4 7.2 0.0 3.0 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.20 KOS22502.1 - 0.014 14.9 0.2 7.8 6.1 0.0 3.3 3 0 0 3 3 3 0 Kelch motif AA_permease_2 PF13520.1 KOS22503.1 - 1.4e-42 145.7 25.1 1.4e-40 139.1 17.4 2.1 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KOS22503.1 - 1.1e-17 63.6 17.6 1.1e-17 63.6 12.2 2.1 2 1 0 2 2 2 1 Amino acid permease Myb_DNA-bind_6 PF13921.1 KOS22504.1 - 0.022 14.8 1.5 0.076 13.1 0.2 2.1 1 1 1 2 2 2 0 Myb-like DNA-binding domain DUF3516 PF12029.3 KOS22504.1 - 0.058 12.2 0.5 0.059 12.1 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) Abhydrolase_5 PF12695.2 KOS22505.1 - 5.2e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Aldedh PF00171.17 KOS22506.1 - 1.4e-176 587.4 0.3 1.5e-176 587.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KOS22506.1 - 0.00012 21.4 0.1 0.21 10.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) PI3Ka PF00613.15 KOS22507.1 - 3.5e-58 195.8 0.1 5.6e-58 195.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KOS22507.1 - 7.6e-43 146.6 0.1 1.3e-41 142.6 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SRP-alpha_N PF04086.8 KOS22508.1 - 4.9e-66 222.9 0.0 7e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 KOS22508.1 - 4.2e-52 176.4 0.1 6.9e-52 175.7 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 KOS22508.1 - 8.4e-08 32.2 0.1 3.6e-07 30.1 0.2 2.0 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 KOS22508.1 - 7.2e-06 24.9 0.0 1.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 KOS22508.1 - 0.00045 19.6 0.2 0.0012 18.2 0.1 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 KOS22508.1 - 0.01 15.5 0.5 0.026 14.2 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KOS22508.1 - 0.025 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 KOS22508.1 - 0.047 13.6 0.1 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 KOS22508.1 - 0.074 13.3 0.0 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.1 KOS22508.1 - 0.094 12.8 0.0 4.5 7.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain YIF1 PF03878.10 KOS22509.1 - 4.1e-78 261.8 1.9 4.9e-78 261.5 1.3 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 KOS22509.1 - 0.0014 18.1 9.2 0.0017 17.8 5.8 1.5 2 0 0 2 2 2 1 Yip1 domain Mid2 PF04478.7 KOS22511.1 - 8e-05 22.0 0.3 0.00014 21.3 0.2 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF3040 PF11239.3 KOS22513.1 - 0.14 12.1 5.4 6.8 6.8 0.4 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Tht1 PF04163.7 KOS22513.1 - 0.35 9.2 3.2 0.6 8.4 2.2 1.3 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein 2OG-FeII_Oxy_2 PF13532.1 KOS22514.1 - 1.4e-27 96.7 0.0 1.8e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KOS22514.1 - 3.3e-05 24.0 0.0 6.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Met_10 PF02475.11 KOS22515.1 - 1.6e-68 230.2 0.0 2.2e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 KOS22515.1 - 0.091 13.3 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF1752 PF08550.5 KOS22516.1 - 1e-09 37.7 1.7 1.9e-09 36.8 1.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RNB PF00773.14 KOS22517.1 - 3.2e-48 164.6 0.0 5e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 RNB domain Pept_tRNA_hydro PF01195.14 KOS22518.1 - 7.3e-19 67.9 0.0 8.9e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase BAR PF03114.13 KOS22519.1 - 3.6e-62 209.8 2.6 4.4e-62 209.5 1.8 1.1 1 0 0 1 1 1 1 BAR domain Dicty_REP PF05086.7 KOS22521.1 - 0.82 7.3 8.4 0.95 7.1 5.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Fungal_trans PF04082.13 KOS22522.1 - 3.1e-11 42.6 4.2 5.1e-11 41.9 2.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS22522.1 - 1.5e-10 40.8 10.4 2.4e-10 40.1 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_47 PF01532.15 KOS22523.1 - 6.6e-142 473.3 0.0 7.5e-142 473.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DCP1 PF06058.8 KOS22524.1 - 1.6e-18 66.8 0.0 2.5e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family Exo_endo_phos PF03372.18 KOS22525.1 - 2.5e-16 60.3 0.0 4e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4232 PF14016.1 KOS22525.1 - 0.0047 16.5 0.1 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4232) DPBB_1 PF03330.13 KOS22526.1 - 5.1e-06 26.4 0.9 6.6e-05 22.8 0.6 2.1 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Viral_helicase1 PF01443.13 KOS22526.1 - 0.15 11.6 0.1 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sugar_tr PF00083.19 KOS22528.1 - 1.7e-80 270.8 29.7 2e-80 270.6 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS22528.1 - 3.1e-18 65.6 37.4 7.1e-14 51.2 20.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 KOS22528.1 - 0.0033 16.2 6.6 0.0033 16.2 4.6 1.8 2 0 0 2 2 2 1 PUCC protein Sugar_tr PF00083.19 KOS22529.1 - 8.3e-84 281.7 22.7 1.1e-83 281.3 15.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS22529.1 - 1.1e-16 60.5 40.3 3.6e-12 45.6 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Arrestin_C PF02752.17 KOS22530.1 - 1.4e-15 57.6 1.1 2.9e-15 56.5 0.0 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain zf-ZPR1 PF03367.8 KOS22531.1 - 1.1e-104 346.4 0.0 5.4e-52 175.1 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Rpr2 PF04032.11 KOS22532.1 - 1.2e-11 44.3 0.2 2.5e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain PPR_2 PF13041.1 KOS22533.1 - 7.6e-07 29.0 0.1 0.006 16.5 0.0 3.6 3 0 0 3 3 3 2 PPR repeat family PPR_1 PF12854.2 KOS22533.1 - 7.6e-05 22.0 0.5 0.0021 17.4 0.0 2.9 2 1 1 3 3 3 1 PPR repeat PPR PF01535.15 KOS22533.1 - 0.00035 20.3 1.6 0.33 11.0 0.0 4.6 4 0 0 4 4 4 1 PPR repeat GDPD PF03009.12 KOS22534.1 - 1e-69 234.9 0.0 1.6e-69 234.2 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KOS22534.1 - 9e-30 102.8 0.5 7.4e-10 39.0 0.1 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KOS22534.1 - 1e-26 92.7 1.9 4e-09 36.7 0.0 6.1 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 KOS22534.1 - 2.7e-24 83.7 3.2 4.5e-07 29.3 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KOS22534.1 - 1.1e-21 76.3 2.2 2.7e-07 30.5 0.0 5.6 3 2 3 6 6 6 4 Ankyrin repeats (many copies) SPX PF03105.14 KOS22534.1 - 5.6e-15 55.8 0.9 7.7e-09 35.7 0.0 2.5 1 1 1 2 2 2 2 SPX domain Ank_3 PF13606.1 KOS22534.1 - 1.4e-13 49.6 2.0 4.3e-05 23.3 0.0 6.5 7 0 0 7 7 7 2 Ankyrin repeat Env-gp36 PF09590.5 KOS22534.1 - 0.027 12.6 0.0 0.041 12.0 0.0 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein zf-H2C2_2 PF13465.1 KOS22535.1 - 4.5e-22 77.1 20.5 7.4e-08 32.3 0.7 4.7 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 KOS22535.1 - 5.6e-19 67.2 32.5 6.7e-06 26.1 0.8 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS22535.1 - 4.6e-10 39.1 27.3 0.00027 21.0 0.6 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KOS22535.1 - 0.00015 21.8 6.8 0.82 9.9 0.3 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS22535.1 - 0.0034 17.5 11.2 0.0046 17.1 0.3 4.5 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KOS22535.1 - 0.06 13.7 14.2 0.073 13.4 2.0 3.3 1 1 2 3 3 3 0 TRAF-type zinc finger Ogr_Delta PF04606.7 KOS22535.1 - 0.089 12.4 3.0 2.3 7.9 0.2 2.7 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-C2HC_2 PF13913.1 KOS22535.1 - 1.4 8.6 6.0 26 4.6 0.4 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type RPAP2_Rtr1 PF04181.8 KOS22535.1 - 2.6 8.2 10.6 72 3.5 7.4 2.6 1 1 0 1 1 1 0 Rtr1/RPAP2 family Peptidase_M41 PF01434.13 KOS22536.1 - 1.8e-65 220.3 0.8 2.9e-65 219.6 0.6 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KOS22536.1 - 2.5e-42 144.2 0.0 5.6e-42 143.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS22536.1 - 2.6e-06 27.2 0.0 7.7e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KOS22536.1 - 1.1e-05 26.2 0.0 3.2e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS22536.1 - 2.1e-05 24.5 1.8 0.00044 20.2 1.2 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KOS22536.1 - 2.7e-05 24.3 2.2 0.00082 19.5 0.2 3.3 3 1 0 3 3 2 1 AAA domain TIP49 PF06068.8 KOS22536.1 - 6.4e-05 21.8 0.0 0.00012 20.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KOS22536.1 - 0.00011 21.3 0.0 0.00023 20.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KOS22536.1 - 0.00059 19.7 0.0 0.0019 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS22536.1 - 0.00087 18.9 0.1 0.0024 17.5 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KOS22536.1 - 0.0016 17.8 0.4 0.0048 16.3 0.1 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 KOS22536.1 - 0.0035 16.7 1.3 0.21 10.9 0.2 2.6 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 KOS22536.1 - 0.0042 16.9 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KOS22536.1 - 0.0045 16.1 0.7 0.017 14.2 0.2 2.1 1 1 1 2 2 2 1 Zeta toxin AAA_28 PF13521.1 KOS22536.1 - 0.016 15.1 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KOS22536.1 - 0.021 14.4 0.6 0.96 9.0 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 KOS22536.1 - 0.034 13.2 0.3 0.034 13.2 0.2 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SpoU_sub_bind PF08032.7 KOS22536.1 - 0.04 14.0 0.2 9.2 6.5 0.0 2.9 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding AAA_18 PF13238.1 KOS22536.1 - 0.061 13.6 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KOS22536.1 - 0.068 13.0 0.0 0.26 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 KOS22536.1 - 0.081 12.9 0.0 0.34 10.9 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 KOS22536.1 - 0.11 11.6 0.4 0.24 10.6 0.3 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF780 PF05611.6 KOS22536.1 - 3.7 8.3 9.0 0.46 11.2 2.8 2.1 2 0 0 2 2 1 0 Caenorhabditis elegans protein of unknown function (DUF780) Epimerase PF01370.16 KOS22537.1 - 5.4e-18 65.3 0.0 6.9e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KOS22537.1 - 6.4e-12 44.7 0.0 8.4e-12 44.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KOS22537.1 - 3e-10 39.4 0.0 6e-10 38.4 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KOS22537.1 - 8.4e-10 38.9 3.6 1.8e-09 37.8 2.5 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KOS22537.1 - 1.1e-07 31.9 1.6 1.8e-07 31.2 1.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS22537.1 - 2.5e-06 27.2 0.6 4.1e-06 26.5 0.4 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KOS22537.1 - 0.00012 21.4 0.1 0.00018 20.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.12 KOS22537.1 - 0.0031 17.9 0.1 0.0088 16.4 0.0 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 KOS22537.1 - 0.052 12.4 0.1 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short_C2 PF13561.1 KOS22538.1 - 1.5e-31 110.0 0.9 1.8e-31 109.7 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KOS22538.1 - 6.4e-30 104.2 1.3 8.3e-30 103.8 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS22538.1 - 3.6e-10 39.7 2.6 2.2e-09 37.2 1.8 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KOS22538.1 - 2.5e-08 33.6 0.1 3.6e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DNA_pol_lambd_f PF10391.4 KOS22538.1 - 0.14 11.7 0.1 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda ORC6 PF05460.8 KOS22539.1 - 3.5e-34 118.4 6.3 1.5e-32 113.0 0.2 2.0 2 0 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) UPF0020 PF01170.13 KOS22540.1 - 9.4e-11 41.6 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KOS22540.1 - 6.9e-08 32.5 0.0 2.3e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Mago_nashi PF02792.9 KOS22541.1 - 3.1e-75 250.6 0.2 3.6e-75 250.4 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Ish1 PF10281.4 KOS22542.1 - 1.1e-75 249.1 7.3 1.3e-15 57.0 0.0 8.6 8 0 0 8 8 8 7 Putative stress-responsive nuclear envelope protein SAP PF02037.22 KOS22542.1 - 1.3e-11 43.7 0.0 0.33 10.5 0.0 6.7 7 0 0 7 7 7 3 SAP domain Slx4 PF09494.5 KOS22542.1 - 2.3e-05 24.0 1.5 7.6 6.3 0.0 5.3 5 0 0 5 5 5 1 Slx4 endonuclease HeH PF12949.2 KOS22542.1 - 0.00021 20.7 0.0 9.5 5.8 0.0 5.2 6 0 0 6 6 6 1 HeH/LEM domain APC2 PF08672.6 KOS22542.1 - 0.00046 20.3 1.1 9.2 6.6 0.0 5.0 6 0 0 6 6 6 1 Anaphase promoting complex (APC) subunit 2 DUF905 PF06006.7 KOS22542.1 - 0.021 14.1 1.3 0.058 12.7 0.1 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF905) EF-hand_9 PF14658.1 KOS22542.1 - 0.13 12.1 0.0 39 4.2 0.0 3.2 2 1 1 3 3 3 0 EF-hand domain DUF1470 PF07336.6 KOS22542.1 - 0.28 11.5 14.7 4.2 7.7 1.7 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1470) SAM_2 PF07647.12 KOS22542.1 - 0.56 10.0 3.0 1.4 8.8 0.1 3.2 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) Lipase3_N PF03893.11 KOS22542.1 - 0.8 9.5 3.8 5 7.0 0.3 3.3 3 1 0 3 3 3 0 Lipase 3 N-terminal region AAA PF00004.24 KOS22543.1 - 1.3e-39 135.3 0.0 2.8e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS22543.1 - 0.00014 21.5 0.9 0.0011 18.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KOS22543.1 - 0.00034 19.7 0.0 0.00074 18.6 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KOS22543.1 - 0.00052 20.0 0.0 0.037 14.0 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KOS22543.1 - 0.0017 18.4 0.2 0.076 13.1 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 KOS22543.1 - 0.0049 16.7 3.0 0.0078 16.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 KOS22543.1 - 0.0091 15.1 0.1 0.03 13.4 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KOS22543.1 - 0.0092 15.2 0.3 0.081 12.1 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.8 KOS22543.1 - 0.014 14.3 0.0 0.03 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 KOS22543.1 - 0.028 14.1 0.3 0.072 12.8 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 KOS22543.1 - 0.042 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KOS22543.1 - 0.047 13.1 0.1 0.099 12.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 KOS22543.1 - 0.064 12.3 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 KOS22543.1 - 0.1 11.9 1.4 0.77 9.1 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.1 KOS22543.1 - 0.17 11.3 1.1 0.57 9.7 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 KOS22543.1 - 0.24 12.2 2.7 0.52 11.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain tRNA-synt_1c PF00749.16 KOS22544.1 - 1.7e-95 319.2 0.0 2.4e-95 318.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KOS22544.1 - 6.8e-28 97.4 0.0 2.2e-27 95.8 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain BOP1NT PF08145.7 KOS22545.1 - 3.3e-104 348.2 5.6 3.3e-104 348.2 3.9 1.6 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.27 KOS22545.1 - 7.3e-32 108.1 5.0 7.4e-15 54.1 0.4 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF3312 PF11768.3 KOS22545.1 - 0.11 10.7 0.0 0.32 9.1 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3312) TFIIA PF03153.8 KOS22545.1 - 2.9 7.6 31.6 4.7 7.0 21.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1510 PF07423.6 KOS22545.1 - 8.9 5.6 20.3 16 4.8 14.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAPS PF04499.10 KOS22545.1 - 9.2 4.7 6.4 14 4.1 4.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_lig_T4_1 PF09511.5 KOS22546.1 - 4.8e-78 261.6 0.0 9.1e-78 260.7 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 KOS22546.1 - 7.3e-67 225.2 0.0 1.1e-66 224.6 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 KOS22546.1 - 3.3e-32 111.6 0.0 1.1e-25 90.3 0.0 2.7 2 1 1 3 3 3 2 tRNA ligase kinase domain Ank_5 PF13857.1 KOS22547.1 - 1.3e-10 41.1 0.1 4.7e-07 29.8 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KOS22547.1 - 1.3e-09 38.2 0.0 2.7e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KOS22547.1 - 1.1e-06 28.8 0.2 0.00037 20.7 0.1 2.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KOS22547.1 - 5.6e-06 26.0 0.6 0.034 14.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 KOS22547.1 - 2.6e-05 23.8 0.0 0.0093 15.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat GCV_T PF01571.16 KOS22547.1 - 0.012 14.9 0.1 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain DnaB_bind PF10410.4 KOS22547.1 - 0.089 12.7 0.2 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Ribosomal_L10 PF00466.15 KOS22548.1 - 0.015 15.2 0.1 0.17 11.8 0.0 2.2 2 1 0 2 2 2 0 Ribosomal protein L10 DUF4400 PF14348.1 KOS22548.1 - 2.8 7.2 6.3 9.3 5.5 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4400) RabGAP-TBC PF00566.13 KOS22550.1 - 5.2e-46 156.8 0.0 8e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 KOS22550.1 - 0.00078 19.1 0.6 0.077 12.9 0.3 3.6 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.1 KOS22550.1 - 0.017 15.2 0.2 0.13 12.3 0.1 2.4 1 1 0 1 1 1 0 EF-hand domain pair GRAM PF02893.15 KOS22550.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.7 1 1 0 1 1 1 0 GRAM domain Pal1 PF08316.6 KOS22551.1 - 4e-46 156.9 1.0 7.8e-46 156.0 0.7 1.5 1 0 0 1 1 1 1 Pal1 cell morphology protein Exo_endo_phos PF03372.18 KOS22552.1 - 1.1e-16 61.5 0.0 1.8e-16 60.8 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 KOS22553.1 - 2.8e-65 220.0 0.0 3.3e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS22553.1 - 1.2e-30 106.4 0.0 1.5e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS22553.1 - 1.6e-05 24.0 0.0 2.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS22553.1 - 0.00012 21.8 0.1 0.0051 16.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KOS22553.1 - 0.0036 16.1 0.0 0.0055 15.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 HrcA_DNA-bdg PF03444.10 KOS22554.1 - 7.3 6.1 6.9 0.63 9.5 0.9 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Pkinase PF00069.20 KOS22555.1 - 1.5e-38 132.4 0.0 1.8e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS22555.1 - 8.5e-14 51.2 0.0 1.2e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS22555.1 - 1.3e-05 25.0 0.1 0.0015 18.3 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KOS22555.1 - 0.054 12.2 0.1 0.082 11.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ATP-synt_C PF00137.16 KOS22559.1 - 1.9e-26 91.7 30.1 2.7e-16 59.2 5.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C SAC3_GANP PF03399.11 KOS22560.1 - 0.002 17.6 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PLRV_ORF5 PF01690.12 KOS22560.1 - 4.5 6.2 4.9 7.2 5.6 3.4 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein BTB PF00651.26 KOS22561.1 - 2.1e-08 34.1 0.0 3.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Sigma70_ner PF04546.8 KOS22562.1 - 0.21 11.1 4.5 0.3 10.6 3.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 KOS22562.1 - 2.7 5.8 7.3 3 5.6 5.1 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KOS22562.1 - 6.8 6.1 12.1 11 5.5 8.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin SET PF00856.23 KOS22565.1 - 1.3e-20 74.3 0.0 7.6e-20 71.8 0.0 2.0 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 KOS22565.1 - 6.4e-19 68.1 1.1 1.1e-17 64.1 0.4 2.3 2 0 0 2 2 2 1 Pre-SET motif Dapper PF15268.1 KOS22566.1 - 0.15 10.8 45.1 0.026 13.3 27.4 1.9 2 0 0 2 2 2 0 Dapper LUC7 PF03194.10 KOS22567.1 - 2.3e-71 240.2 2.5 2.8e-71 240.0 1.7 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.16 KOS22567.1 - 0.0019 17.7 0.1 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1241 PF06840.6 KOS22567.1 - 0.0062 15.7 0.2 0.025 13.8 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1241) AAA_13 PF13166.1 KOS22567.1 - 0.024 13.1 0.8 0.03 12.7 0.5 1.2 1 0 0 1 1 1 0 AAA domain zf-C4H2 PF10146.4 KOS22567.1 - 0.026 14.5 0.5 0.033 14.2 0.3 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein AIG1 PF04548.11 KOS22567.1 - 0.12 11.5 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 AIG1 family Occludin_ELL PF07303.8 KOS22567.1 - 0.49 11.1 4.9 0.27 11.9 0.6 2.3 2 1 0 2 2 2 0 Occludin homology domain FadA PF09403.5 KOS22567.1 - 2.7 8.0 5.0 10 6.1 1.4 2.2 1 1 1 2 2 2 0 Adhesion protein FadA Nuc_deoxyrib_tr PF05014.10 KOS22569.1 - 5.9e-05 22.9 0.0 8.8e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase DUF772 PF05598.6 KOS22570.1 - 0.08 12.8 0.0 9.5 6.2 0.0 2.5 2 0 0 2 2 2 0 Transposase domain (DUF772) Tetraspannin PF00335.15 KOS22572.1 - 0.00015 21.1 2.1 0.001 18.3 0.0 2.1 2 0 0 2 2 2 1 Tetraspanin family NADHdeh_related PF10125.4 KOS22572.1 - 0.36 9.9 2.1 0.53 9.4 1.5 1.3 1 0 0 1 1 1 0 NADH dehydrogenase I, subunit N related protein DUF1772 PF08592.6 KOS22572.1 - 6.2 6.5 11.1 1.6 8.4 4.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) Aldedh PF00171.17 KOS22573.1 - 1.2e-185 617.3 0.1 1.3e-185 617.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KOS22573.1 - 0.056 12.6 0.1 1.1 8.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) PIGA PF08288.7 KOS22574.1 - 1.1e-46 157.0 2.6 1.8e-46 156.4 0.5 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KOS22574.1 - 2e-29 102.2 0.0 3e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KOS22574.1 - 6.5e-16 58.7 0.0 1.3e-15 57.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KOS22574.1 - 7.9e-15 55.0 0.2 1.4e-14 54.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KOS22574.1 - 2e-12 47.5 0.0 3.2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 KOS22574.1 - 1e-05 25.3 0.2 1.9e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 KOS22574.1 - 0.0051 17.0 0.0 0.017 15.3 0.0 1.9 2 0 0 2 2 1 1 Glycosyl transferases group 1 SSP160 PF06933.6 KOS22574.1 - 0.026 12.5 8.1 0.035 12.1 5.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.6 KOS22574.1 - 1.4 6.6 5.4 1.9 6.2 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dicty_REP PF05086.7 KOS22574.1 - 1.6 6.4 3.8 0.89 7.2 1.5 1.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 KOS22574.1 - 2.8 7.7 19.7 5.1 6.8 13.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DEAD PF00270.24 KOS22575.1 - 3.5e-31 107.9 0.0 1.7e-14 53.6 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS22575.1 - 2.8e-19 68.7 0.0 7.8e-19 67.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS22575.1 - 6.2e-09 35.9 0.0 6.2e-09 35.9 0.0 3.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Acyl_transf_1 PF00698.16 KOS22576.1 - 8.3e-69 232.3 0.0 1.3e-68 231.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KOS22576.1 - 5.6e-60 202.9 1.4 2.7e-59 200.7 0.1 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KOS22576.1 - 8.7e-58 194.9 0.3 2.6e-57 193.4 0.1 2.0 2 0 0 2 2 1 1 KR domain PS-DH PF14765.1 KOS22576.1 - 1.5e-56 191.7 0.0 2.3e-56 191.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KOS22576.1 - 4.9e-46 156.6 0.7 2.8e-45 154.2 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KOS22576.1 - 7.2e-32 109.7 0.3 1.7e-31 108.5 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KOS22576.1 - 5.5e-18 65.2 0.0 1.2e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KOS22576.1 - 1.2e-16 60.3 0.0 3.4e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KOS22576.1 - 2.3e-12 47.8 0.0 3.1e-11 44.2 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KOS22576.1 - 6.7e-12 45.4 0.0 2.1e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS22576.1 - 1.4e-10 40.9 0.0 3.7e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS22576.1 - 1.6e-07 31.8 0.0 4.1e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KOS22576.1 - 4.1e-07 29.7 0.4 1.1e-06 28.3 0.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 KOS22576.1 - 3.3e-06 27.4 0.0 8.5e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KOS22576.1 - 0.00013 22.2 0.1 0.0006 20.0 0.1 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 KOS22576.1 - 0.00056 19.0 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KOS22576.1 - 0.003 16.5 0.8 0.0048 15.9 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_28 PF02636.12 KOS22576.1 - 0.082 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 KOS22576.1 - 0.092 12.1 0.1 0.41 10.0 0.0 2.1 2 1 0 2 2 2 0 Putative methyltransferase Thioesterase PF00975.15 KOS22577.1 - 9.9e-11 42.2 0.0 1e-10 42.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 KOS22577.1 - 0.084 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Engrail_1_C_sig PF10525.4 KOS22578.1 - 0.44 9.7 1.5 0.99 8.5 1.1 1.5 1 0 0 1 1 1 0 Engrailed homeobox C-terminal signature domain Lyase_1 PF00206.15 KOS22579.1 - 2.1e-24 86.3 0.1 5.1e-24 85.0 0.0 1.6 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.4 KOS22579.1 - 3.3e-12 46.2 0.1 2.3e-11 43.5 0.0 2.4 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus KOW PF00467.24 KOS22580.1 - 7.3e-08 31.8 1.8 1.9e-07 30.4 1.2 1.7 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.6 KOS22580.1 - 0.014 15.2 0.3 0.015 15.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) GHL5 PF14872.1 KOS22580.1 - 0.091 10.5 0.0 0.093 10.4 0.0 1.0 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Ribosomal_L32p PF01783.18 KOS22580.1 - 0.26 11.4 2.0 0.59 10.3 1.4 1.6 1 0 0 1 1 1 0 Ribosomal L32p protein family Rad51 PF08423.6 KOS22581.1 - 2.2e-24 85.7 0.0 3.4e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KOS22581.1 - 2.3e-10 40.1 0.2 4.4e-10 39.2 0.2 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KOS22581.1 - 8.6e-10 38.1 1.0 5.8e-08 32.1 0.7 2.1 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KOS22581.1 - 4.8e-05 22.5 0.0 6.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 KaiC ABC_tran PF00005.22 KOS22581.1 - 0.086 13.1 0.1 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RNA_pol_Rpb2_6 PF00562.23 KOS22582.1 - 2.4e-117 391.9 0.0 4.2e-117 391.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KOS22582.1 - 1.6e-52 177.3 0.5 2.9e-52 176.5 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KOS22582.1 - 8.5e-29 99.6 0.2 2.1e-28 98.3 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 KOS22582.1 - 1.4e-28 99.6 0.1 4e-28 98.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KOS22582.1 - 2.3e-21 75.3 0.0 4.4e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KOS22582.1 - 5.9e-20 70.8 0.2 1.5e-19 69.5 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KOS22582.1 - 5.4e-11 42.2 0.8 1.5e-10 40.8 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_L15e PF00827.12 KOS22583.1 - 2.1e-82 275.2 8.8 2.9e-82 274.8 6.1 1.2 1 0 0 1 1 1 1 Ribosomal L15 PUCC PF03209.10 KOS22584.1 - 0.16 10.6 0.1 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 PUCC protein RasGEF PF00617.14 KOS22585.1 - 7.4e-46 156.2 0.1 2.2e-45 154.7 0.0 1.7 2 0 0 2 2 2 1 RasGEF domain Miro PF08477.8 KOS22585.1 - 1.4e-13 51.3 0.0 1.1e-12 48.5 0.0 2.4 3 0 0 3 3 3 1 Miro-like protein RasGEF_N PF00618.15 KOS22585.1 - 8e-11 41.9 0.1 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif AAA_22 PF13401.1 KOS22585.1 - 0.0022 18.1 0.0 0.83 9.8 0.0 3.5 5 0 0 5 5 5 1 AAA domain AAA_33 PF13671.1 KOS22585.1 - 0.018 14.8 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KOS22585.1 - 0.022 15.0 0.0 0.066 13.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Ras PF00071.17 KOS22585.1 - 0.025 13.9 0.0 0.24 10.7 0.0 2.4 2 1 0 2 2 2 0 Ras family AAA_29 PF13555.1 KOS22585.1 - 0.046 13.2 0.0 0.28 10.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 KOS22585.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.18 KOS22585.1 - 0.094 12.6 0.0 0.26 11.2 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 KOS22585.1 - 0.25 12.1 1.5 1.5 9.6 0.0 3.0 3 1 0 3 3 3 0 AAA domain Nfu_N PF08712.6 KOS22588.1 - 3.3e-28 97.1 0.0 6.7e-28 96.1 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KOS22588.1 - 2.4e-21 75.2 0.0 3.9e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain Carn_acyltransf PF00755.15 KOS22589.1 - 1.9e-163 544.7 0.0 3.2e-148 494.4 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase NTPase_I-T PF01931.13 KOS22590.1 - 0.00093 18.9 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF84 RRM_5 PF13893.1 KOS22591.1 - 2.1e-09 37.0 0.0 3.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS22591.1 - 1.1e-07 31.4 0.0 1.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS22591.1 - 1.6e-06 27.9 0.1 2.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Serglycin PF04360.7 KOS22591.1 - 0.011 15.4 8.4 0.021 14.5 5.8 1.4 1 0 0 1 1 1 0 Serglycin Citrate_synt PF00285.16 KOS22592.1 - 1e-101 340.2 0.0 1.2e-101 340.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 KOS22592.1 - 0.0078 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Eclosion hormone Nic96 PF04097.9 KOS22593.1 - 2.8e-203 676.4 0.0 3.4e-203 676.1 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 KOS22593.1 - 4e-12 46.3 97.9 2.8e-09 37.2 34.4 4.4 2 1 2 4 4 4 2 Nucleoporin FG repeat region DUF3425 PF11905.3 KOS22594.1 - 6.3e-25 87.6 1.3 2.6e-24 85.6 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KOS22594.1 - 0.0041 17.0 7.9 0.0041 17.0 5.5 1.8 2 0 0 2 2 2 1 bZIP transcription factor OmpH PF03938.9 KOS22594.1 - 0.024 14.5 1.8 0.049 13.5 1.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF904 PF06005.7 KOS22594.1 - 1.9 8.8 7.7 0.43 10.8 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) E1-E2_ATPase PF00122.15 KOS22596.1 - 8.2e-62 208.2 6.6 8.2e-62 208.2 4.6 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KOS22596.1 - 5.3e-22 79.2 0.0 1.1e-21 78.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KOS22596.1 - 1.6e-12 47.9 0.0 4e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KOS22596.1 - 4.9e-10 38.7 0.0 1.2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KOS22596.1 - 0.0014 18.2 0.1 0.0028 17.2 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS22596.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Apc15p PF05841.6 KOS22597.1 - 3e-21 76.4 6.0 3e-21 76.4 4.2 2.1 2 0 0 2 2 2 1 Apc15p protein Glu_synthase PF01645.12 KOS22598.1 - 6.3e-159 528.7 0.0 1.7e-158 527.3 0.0 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KOS22598.1 - 5.1e-141 469.5 0.0 6.9e-141 469.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KOS22598.1 - 4.1e-115 383.9 0.0 7.2e-115 383.1 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 KOS22598.1 - 5.5e-67 224.6 1.3 1.1e-66 223.7 0.9 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 KOS22598.1 - 1.4e-22 79.3 0.1 3.3e-22 78.2 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KOS22598.1 - 1e-16 61.4 0.0 2.7e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KOS22598.1 - 1.7e-09 38.0 0.1 0.0019 18.3 0.0 3.1 2 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS22598.1 - 3.2e-09 36.6 0.6 9e-09 35.2 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KOS22598.1 - 7.4e-08 32.6 0.3 9.9e-05 22.6 0.0 3.2 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KOS22598.1 - 3.7e-07 29.6 0.2 2.3e-06 26.9 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 KOS22598.1 - 1.5e-05 23.7 0.1 1.5e-05 23.7 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 KOS22598.1 - 3.5e-05 22.8 0.1 3.5e-05 22.8 0.1 2.4 2 1 0 2 2 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KOS22598.1 - 6.3e-05 21.9 0.1 0.00022 20.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KOS22598.1 - 0.0001 21.5 0.0 0.00021 20.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KOS22598.1 - 0.00013 22.1 0.1 1.2 9.4 0.0 3.2 3 0 0 3 3 2 2 Putative NAD(P)-binding FMO-like PF00743.14 KOS22598.1 - 0.0014 16.8 0.2 0.35 9.0 0.0 2.8 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.14 KOS22598.1 - 0.0015 17.7 0.0 0.0031 16.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 KOS22598.1 - 0.0035 16.9 0.1 0.12 11.8 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KOS22598.1 - 0.0041 16.2 0.1 0.013 14.6 0.0 1.8 1 0 0 1 1 1 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 KOS22598.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.16 KOS22598.1 - 0.019 14.7 0.2 7.3 6.4 0.0 2.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Lycopene_cycl PF05834.7 KOS22598.1 - 0.031 13.2 0.1 0.79 8.5 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 KOS22598.1 - 0.048 13.7 0.2 4.3 7.4 0.0 2.7 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KOS22598.1 - 0.06 12.1 1.2 0.15 10.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KOS22598.1 - 0.064 13.0 0.0 0.33 10.7 0.0 2.3 2 0 0 2 2 1 0 FAD-NAD(P)-binding F420_oxidored PF03807.12 KOS22598.1 - 0.073 13.5 0.1 0.98 9.8 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Phage_GPO PF05929.6 KOS22598.1 - 0.084 12.1 0.4 0.13 11.4 0.2 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FMN_dh PF01070.13 KOS22598.1 - 0.088 11.6 0.8 0.41 9.4 0.5 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase 3HCDH_N PF02737.13 KOS22598.1 - 0.64 9.6 2.2 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain VTC PF09359.5 KOS22599.1 - 1.8e-90 302.7 0.7 3.2e-90 301.9 0.5 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KOS22599.1 - 5.8e-20 72.1 10.8 3.2e-19 69.7 4.5 3.3 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 KOS22599.1 - 6.8e-09 35.8 1.3 6.8e-09 35.8 0.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) FGGY_C PF02782.11 KOS22600.1 - 4.5e-46 156.9 1.2 7.9e-46 156.1 0.9 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KOS22600.1 - 1e-26 93.7 1.8 4.8e-23 81.7 0.0 2.9 3 1 0 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KOS22600.1 - 0.022 14.0 0.2 0.056 12.7 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family IBR PF01485.16 KOS22601.1 - 4.4e-21 74.5 19.9 4.1e-12 45.7 0.6 3.6 3 1 0 3 3 3 2 IBR domain TF_Zn_Ribbon PF08271.7 KOS22601.1 - 0.087 12.1 0.4 0.087 12.1 0.3 3.8 4 0 0 4 4 4 0 TFIIB zinc-binding Nop14 PF04147.7 KOS22601.1 - 0.36 8.6 4.3 0.45 8.3 3.0 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 KOS22601.1 - 3.2 6.6 5.4 4.5 6.1 3.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.7 KOS22601.1 - 3.9 6.6 7.9 6.4 5.9 5.5 1.3 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.7 KOS22601.1 - 6.2 5.0 8.5 9.8 4.4 5.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.5 KOS22601.1 - 7.7 5.4 6.5 13 4.7 4.5 1.3 1 0 0 1 1 1 0 BUD22 HSP70 PF00012.15 KOS22602.1 - 4.7e-08 31.4 0.6 4.9e-06 24.7 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein Hydantoinase_A PF01968.13 KOS22602.1 - 0.023 13.8 0.4 0.31 10.1 0.1 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.15 KOS22602.1 - 0.048 12.9 0.1 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M22 PF00814.20 KOS22602.1 - 0.051 13.0 0.0 0.11 12.0 0.0 1.5 2 0 0 2 2 2 0 Glycoprotease family PUCC PF03209.10 KOS22602.1 - 0.069 11.8 0.0 0.09 11.4 0.0 1.1 1 0 0 1 1 1 0 PUCC protein DOCK-C2 PF14429.1 KOS22603.1 - 3.4e-15 56.1 0.0 5.9e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KOS22603.1 - 2.4e-06 26.9 0.0 2.4e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Dedicator of cytokinesis SH3_1 PF00018.23 KOS22603.1 - 5.7e-06 25.6 0.0 1.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KOS22603.1 - 0.0019 17.7 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KOS22603.1 - 0.19 11.2 0.0 0.57 9.7 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain Acetyltransf_5 PF13444.1 KOS22604.1 - 0.00024 21.6 0.1 0.86 10.2 0.0 2.9 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS22604.1 - 0.00026 20.9 0.3 0.00084 19.3 0.2 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS22604.1 - 0.036 14.2 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2236 PF09995.4 KOS22605.1 - 0.062 12.5 0.1 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) tRNA-synt_1 PF00133.17 KOS22606.1 - 1.5e-39 135.5 0.0 2.4e-28 98.5 0.0 3.3 2 2 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KOS22606.1 - 6.3e-17 61.3 0.1 8e-11 41.2 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KOS22606.1 - 1.3e-10 41.2 0.3 2.8e-10 40.1 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KOS22606.1 - 8e-08 31.7 0.0 1.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Adeno_hexon_C PF03678.9 KOS22606.1 - 0.031 13.7 0.1 0.28 10.6 0.0 2.3 3 0 0 3 3 3 0 Hexon, adenovirus major coat protein, C-terminal domain zf-CSL PF05207.8 KOS22607.1 - 3.2e-26 90.5 1.1 3.8e-26 90.3 0.7 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 KOS22607.1 - 0.026 14.4 0.1 0.044 13.7 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 KOS22607.1 - 0.026 13.8 0.3 0.05 12.9 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RING_4 PF14570.1 KOS22607.1 - 0.038 13.5 0.3 0.055 13.0 0.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 KOS22607.1 - 2.5 7.8 4.6 7.9 6.2 3.2 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 ABC_membrane_2 PF06472.10 KOS22608.1 - 3.7e-107 357.6 4.2 7e-107 356.7 2.0 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KOS22608.1 - 1.4e-17 64.3 0.0 2.7e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KOS22608.1 - 0.0022 18.0 0.0 0.0065 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KOS22608.1 - 0.031 14.5 0.1 0.096 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KOS22608.1 - 0.04 13.1 0.0 0.11 11.6 0.0 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KOS22608.1 - 0.042 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KOS22608.1 - 0.1 12.5 0.4 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.16 KOS22608.1 - 0.15 11.2 0.1 0.43 9.7 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 KOS22608.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Frataxin_Cyay PF01491.11 KOS22609.1 - 1.2e-33 115.0 0.0 1.7e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Clat_adaptor_s PF01217.15 KOS22610.1 - 1.7e-42 144.4 0.0 3.6e-42 143.4 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain COG5 PF10392.4 KOS22611.1 - 0.053 13.4 0.4 0.52 10.2 0.1 2.5 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Sds3 PF08598.6 KOS22612.1 - 5.3e-41 140.4 4.3 9.3e-41 139.6 3.0 1.4 1 0 0 1 1 1 1 Sds3-like Caudo_TAP PF02413.12 KOS22612.1 - 0.033 14.3 0.8 6.4 6.9 0.0 2.7 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein Glyco_hydro_31 PF01055.21 KOS22613.1 - 8.4e-115 384.0 0.4 1e-114 383.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KOS22613.1 - 4e-16 58.6 0.0 2.1e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like CAP59_mtransfer PF11735.3 KOS22614.1 - 1.3e-61 207.9 0.0 1.7e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 MFS_1 PF07690.11 KOS22615.1 - 6.4e-26 90.9 70.7 3.1e-20 72.2 27.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MS_channel PF00924.13 KOS22616.1 - 4.3e-12 45.8 7.3 1.5e-11 44.0 4.8 2.0 1 1 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KOS22616.1 - 0.00076 18.6 0.2 0.0019 17.3 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KOS22616.1 - 0.00089 19.3 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KOS22616.1 - 0.035 13.4 0.0 0.035 13.4 0.0 1.9 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.1 KOS22616.1 - 0.044 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain DLH PF01738.13 KOS22617.1 - 3.2e-27 95.2 0.0 4.2e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KOS22617.1 - 0.00084 19.1 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KOS22617.1 - 0.057 12.8 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 KOS22617.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abp2 PF09441.5 KOS22618.1 - 1.4e-36 126.0 0.0 1.7e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 ARS binding protein 2 DUF3796 PF12676.2 KOS22618.1 - 0.64 10.2 2.6 0.99 9.6 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) RNA_pol_A_bac PF01000.21 KOS22619.1 - 1.6e-33 115.2 0.0 2.3e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KOS22619.1 - 3.4e-13 48.5 0.0 5e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain WD40 PF00400.27 KOS22620.1 - 3.4e-38 128.1 4.3 2.1e-08 33.7 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 KOS22620.1 - 5e-31 106.5 15.1 9.6e-31 105.6 10.5 1.5 1 0 0 1 1 1 1 Sof1-like domain Cytochrom_D1 PF02239.11 KOS22620.1 - 0.0029 15.9 0.1 0.082 11.1 0.0 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain tRNA-synt_2d PF01409.15 KOS22621.1 - 2.7e-48 164.3 0.4 1.4e-25 89.9 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KOS22621.1 - 2e-25 88.7 0.0 3.9e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.22 KOS22622.1 - 5.5e-48 160.6 0.2 1.7e-17 62.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Neugrin PF06413.6 KOS22623.1 - 3.3e-11 43.4 0.4 3.3e-11 43.4 0.3 2.6 2 1 1 3 3 3 1 Neugrin MRP-L20 PF12824.2 KOS22623.1 - 0.0028 17.6 12.1 0.0028 17.6 8.4 2.7 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 DUF3612 PF12268.3 KOS22623.1 - 0.047 13.4 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) Hid1 PF12722.2 KOS22623.1 - 0.17 9.5 5.3 0.2 9.2 3.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Calcipressin PF04847.7 KOS22624.1 - 2.3e-51 173.9 0.3 2.8e-51 173.7 0.2 1.0 1 0 0 1 1 1 1 Calcipressin Glyco_hydro_72 PF03198.9 KOS22625.1 - 3.2e-74 249.7 0.3 1.6e-72 244.1 0.2 2.1 1 1 0 1 1 1 1 Glucanosyltransferase adh_short PF00106.20 KOS22626.1 - 1.1e-29 103.4 3.2 2.3e-29 102.4 2.2 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS22626.1 - 1.8e-11 44.2 0.0 2.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS22626.1 - 9.1e-11 41.7 4.5 1.2e-09 38.1 3.0 2.5 1 1 1 2 2 2 1 KR domain BioW PF03744.8 KOS22626.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase 6PF2K PF01591.13 KOS22627.1 - 5.1e-66 221.9 0.0 2.2e-45 154.4 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KOS22627.1 - 6.7e-25 88.0 0.0 5.3e-24 85.1 0.0 2.4 2 1 1 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KOS22627.1 - 1.8e-05 24.6 0.0 0.00019 21.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS22627.1 - 0.0047 17.7 0.0 0.036 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 KOS22627.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 WD40 PF00400.27 KOS22629.1 - 1.3e-30 104.1 14.8 4.2e-13 48.6 0.8 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KOS22629.1 - 6.1e-07 29.3 0.0 6.3e-06 26.0 0.0 2.5 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 KOS22629.1 - 0.0025 17.2 0.1 0.01 15.2 0.0 2.1 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 KOS22629.1 - 0.0032 16.2 0.0 0.037 12.7 0.0 2.1 2 0 0 2 2 2 1 Nup133 N terminal like Nbas_N PF15492.1 KOS22629.1 - 0.014 14.5 0.1 1.8 7.5 0.0 3.4 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 KOS22629.1 - 0.021 14.0 0.0 0.95 8.6 0.0 3.0 1 1 2 3 3 3 0 TUP1-like enhancer of split Nup160 PF11715.3 KOS22629.1 - 0.054 11.6 0.0 0.27 9.3 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KOS22629.1 - 0.065 11.5 0.7 1.1 7.4 0.5 2.1 1 1 0 1 1 1 0 Cytochrome D1 heme domain PQQ_3 PF13570.1 KOS22629.1 - 0.87 9.9 3.6 8.2 6.8 0.1 3.6 4 0 0 4 4 4 0 PQQ-like domain Ribosomal_L32p PF01783.18 KOS22630.1 - 3.4e-12 46.3 6.1 4.7e-12 45.9 4.2 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family DUF2419 PF10343.4 KOS22631.1 - 3.6e-117 390.7 0.0 4.5e-117 390.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DNA_pol_delta_4 PF04081.8 KOS22632.1 - 3.9e-08 33.6 0.7 9.9e-08 32.3 0.5 1.6 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Glyco_hydro_72 PF03198.9 KOS22633.1 - 7.7e-107 356.9 0.1 9.5e-107 356.6 0.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 KOS22633.1 - 5.8e-05 22.1 0.2 0.00011 21.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 KOS22633.1 - 0.00045 19.5 0.6 0.0012 18.0 0.4 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ATP-grasp_2 PF08442.5 KOS22634.1 - 1.2e-08 34.5 0.0 2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Septin PF00735.13 KOS22635.1 - 7.7e-111 369.6 0.2 9e-111 369.3 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KOS22635.1 - 2.1e-06 27.6 0.0 3.2e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KOS22635.1 - 5.7e-06 25.5 0.0 9.7e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KOS22635.1 - 3.2e-05 23.1 0.0 5.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KOS22635.1 - 0.00032 20.1 0.1 0.0084 15.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KOS22635.1 - 0.0012 18.6 0.3 1.5 8.6 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 KOS22635.1 - 0.0036 16.7 0.0 0.0048 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 KOS22635.1 - 0.0065 16.8 0.0 0.01 16.2 0.0 1.3 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KOS22635.1 - 0.007 16.6 0.2 0.014 15.6 0.2 1.8 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 KOS22635.1 - 0.023 14.8 0.0 0.057 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 KOS22635.1 - 0.025 13.7 0.1 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 KOS22635.1 - 0.028 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 KOS22635.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KOS22635.1 - 0.15 12.9 0.5 14 6.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 KOS22635.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.16 KOS22636.1 - 2.8e-61 206.1 0.0 3.4e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase DUF258 PF03193.11 KOS22636.1 - 1.4e-06 27.6 0.0 2.2e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KOS22636.1 - 0.00026 20.9 0.0 0.0007 19.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KOS22636.1 - 0.00071 19.8 0.0 0.0027 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KOS22636.1 - 0.0012 19.0 0.0 0.0074 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KOS22636.1 - 0.0014 18.6 0.1 0.0063 16.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 KOS22636.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KOS22636.1 - 0.003 18.3 0.0 0.0061 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KOS22636.1 - 0.023 14.6 0.1 0.67 9.9 0.0 2.5 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 KOS22636.1 - 0.047 13.9 0.1 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.1 KOS22636.1 - 0.054 13.3 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF1895 PF08988.5 KOS22636.1 - 0.091 12.8 0.3 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) adh_short PF00106.20 KOS22637.1 - 1.5e-14 54.2 1.9 8.2e-14 51.8 1.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS22637.1 - 2.2e-14 53.8 0.0 1.2e-08 35.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS22637.1 - 7.3e-08 32.2 0.2 1.7e-07 31.0 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KOS22637.1 - 0.00073 19.0 0.0 0.0017 17.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KOS22637.1 - 0.00089 19.3 0.3 0.0037 17.2 0.1 2.0 2 0 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KOS22637.1 - 0.012 14.5 0.1 0.041 12.7 0.1 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.10 KOS22637.1 - 0.018 14.6 0.1 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein NmrA PF05368.8 KOS22637.1 - 0.024 13.8 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Shikimate_DH PF01488.15 KOS22637.1 - 0.042 13.9 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KOS22637.1 - 0.13 11.8 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PapC_N PF13954.1 KOS22637.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 PapC N-terminal domain Eno-Rase_NADH_b PF12242.3 KOS22637.1 - 0.26 11.0 2.3 0.57 10.0 1.6 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.16 KOS22638.1 - 1.9e-41 141.1 0.1 3.8e-41 140.0 0.1 1.5 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.4 KOS22638.1 - 7.2e-18 63.7 1.9 7.2e-18 63.7 1.3 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 KOS22638.1 - 1.3e-16 60.4 0.5 1.3e-16 60.4 0.4 2.4 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBACT PF02134.16 KOS22638.1 - 1.2e-08 34.3 0.1 3.2e-08 33.0 0.1 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein Shikimate_DH PF01488.15 KOS22638.1 - 0.0044 17.1 0.0 0.0094 16.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KOS22638.1 - 0.065 13.4 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Coprogen_oxidas PF01218.13 KOS22640.1 - 8.1e-131 434.9 0.0 9.9e-131 434.6 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase CAF-1_p150 PF11600.3 KOS22641.1 - 3.8e-05 23.1 26.3 3.8e-05 23.1 18.2 2.0 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 KOS22641.1 - 0.00017 19.5 2.1 0.00022 19.1 1.5 1.0 1 0 0 1 1 1 1 Ycf1 MIP-T3 PF10243.4 KOS22641.1 - 0.0014 17.2 23.6 0.002 16.6 16.4 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 SAPS PF04499.10 KOS22641.1 - 0.024 13.3 3.8 0.031 12.9 2.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 KOS22641.1 - 0.084 10.8 14.9 0.12 10.4 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 KOS22641.1 - 0.12 11.3 2.4 0.19 10.6 1.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CDC27 PF09507.5 KOS22641.1 - 0.49 9.5 21.2 0.71 9.0 14.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GAGA_bind PF06217.7 KOS22641.1 - 1.2 9.0 10.5 1.7 8.5 7.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1510 PF07423.6 KOS22641.1 - 1.3 8.3 16.8 2.1 7.6 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nucleo_P87 PF07267.6 KOS22641.1 - 2.3 6.8 9.9 2.8 6.5 6.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Hex_IIIa PF02455.11 KOS22641.1 - 2.6 6.6 7.0 4.3 5.9 4.9 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) RR_TM4-6 PF06459.7 KOS22641.1 - 2.7 7.8 13.3 4.2 7.1 9.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 KOS22641.1 - 6.6 6.4 10.6 14 5.3 7.3 1.6 1 0 0 1 1 1 0 DDHD domain RF-1 PF00472.15 KOS22642.1 - 2.2e-34 117.6 2.4 3.5e-34 117.0 1.7 1.3 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 KOS22642.1 - 1.2e-21 76.6 0.0 2.7e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 PCRF domain MIR PF02815.14 KOS22642.1 - 0.08 12.4 0.8 0.14 11.6 0.6 1.3 1 0 0 1 1 1 0 MIR domain MFS_1 PF07690.11 KOS22643.1 - 2e-13 49.8 15.0 2.8e-13 49.3 10.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily GAGA_bind PF06217.7 KOS22643.1 - 2.3e-05 24.5 5.9 3.1e-05 24.0 4.1 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family DUF1764 PF08576.5 KOS22643.1 - 0.0007 20.3 7.6 0.0007 20.3 5.2 1.4 2 0 0 2 2 1 1 Eukaryotic protein of unknown function (DUF1764) AUX_IAA PF02309.11 KOS22643.1 - 0.0014 18.3 1.5 0.0018 18.0 1.0 1.1 1 0 0 1 1 1 1 AUX/IAA family Tim54 PF11711.3 KOS22643.1 - 0.0087 14.6 5.0 0.012 14.2 3.5 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Ycf1 PF05758.7 KOS22643.1 - 0.033 11.9 6.9 0.04 11.6 4.8 1.0 1 0 0 1 1 1 0 Ycf1 EPL1 PF10513.4 KOS22643.1 - 0.069 13.4 12.8 0.1 12.8 8.9 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like LMBR1 PF04791.11 KOS22643.1 - 0.069 11.7 0.1 0.073 11.6 0.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF106 PF01956.11 KOS22643.1 - 0.084 12.4 4.0 0.13 11.7 2.8 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 Raftlin PF15250.1 KOS22643.1 - 0.12 10.8 10.3 0.16 10.4 7.1 1.1 1 0 0 1 1 1 0 Raftlin SpoIIP PF07454.6 KOS22643.1 - 0.17 11.0 10.9 0.24 10.5 7.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FimP PF09766.4 KOS22643.1 - 0.25 10.3 26.6 0.37 9.8 18.5 1.2 1 0 0 1 1 1 0 Fms-interacting protein CENP-T PF15511.1 KOS22643.1 - 0.28 10.3 17.5 0.41 9.8 12.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PAT1 PF09770.4 KOS22643.1 - 0.29 9.3 39.0 0.37 8.9 27.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.9 KOS22643.1 - 0.37 8.7 11.6 0.57 8.1 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TMEM51 PF15345.1 KOS22643.1 - 0.39 10.3 12.9 0.71 9.5 8.9 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 eIF-3_zeta PF05091.7 KOS22643.1 - 0.42 9.1 17.3 0.53 8.8 12.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) UPF0560 PF10577.4 KOS22643.1 - 0.47 8.6 23.0 0.59 8.3 15.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Cellulose_synt PF03552.9 KOS22643.1 - 0.48 8.6 4.0 0.65 8.2 2.8 1.1 1 0 0 1 1 1 0 Cellulose synthase Spore_coat_CotO PF14153.1 KOS22643.1 - 0.98 8.8 20.3 1.4 8.3 14.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Plasmodium_Vir PF05795.6 KOS22643.1 - 1 8.5 3.9 1.3 8.1 2.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NARP1 PF12569.3 KOS22643.1 - 1.2 7.8 14.3 1.6 7.4 9.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TFIIA PF03153.8 KOS22643.1 - 1.4 8.7 28.6 1.8 8.3 19.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.7 KOS22643.1 - 1.4 8.7 14.1 1.9 8.3 9.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 vMSA PF00695.14 KOS22643.1 - 1.4 8.0 7.5 1.9 7.6 5.2 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Gti1_Pac2 PF09729.4 KOS22643.1 - 1.7 8.5 9.1 2.5 7.9 6.3 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2201_N PF13203.1 KOS22643.1 - 1.8 7.6 15.7 3 6.9 10.9 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain FLO_LFY PF01698.11 KOS22643.1 - 2.1 7.0 13.3 3 6.5 9.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein FAM60A PF15396.1 KOS22643.1 - 2.2 7.9 10.0 3.2 7.4 6.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Band_3_cyto PF07565.8 KOS22643.1 - 2.8 7.4 14.9 3.9 6.9 10.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Bud13 PF09736.4 KOS22643.1 - 2.9 8.1 20.2 4.5 7.5 14.0 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex PIH1 PF08190.7 KOS22643.1 - 2.9 7.2 19.7 3.9 6.8 13.7 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Herpes_DNAp_acc PF04929.7 KOS22643.1 - 3.2 6.6 10.9 4.4 6.1 7.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FAM222A PF15258.1 KOS22643.1 - 3.9 6.5 28.8 6 5.9 20.0 1.2 1 0 0 1 1 1 0 Protein family of FAM222A Baculo_PP31 PF05311.6 KOS22643.1 - 4.3 6.5 15.1 5.9 6.0 10.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DDHD PF02862.12 KOS22643.1 - 4.4 7.0 14.8 6.6 6.4 10.2 1.2 1 0 0 1 1 1 0 DDHD domain DUF2681 PF10883.3 KOS22643.1 - 4.5 7.5 0.0 4.5 7.5 0.0 3.2 3 1 0 3 3 1 0 Protein of unknown function (DUF2681) Paramyxo_ncap PF00973.14 KOS22643.1 - 4.7 5.8 9.5 5.9 5.4 6.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF2126 PF09899.4 KOS22643.1 - 4.8 5.0 10.5 6.4 4.6 7.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF3533 PF12051.3 KOS22643.1 - 4.9 5.7 8.5 7 5.2 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) FAM176 PF14851.1 KOS22643.1 - 5 6.7 10.7 40 3.8 6.9 2.3 2 0 0 2 2 2 0 FAM176 family DUF4638 PF15472.1 KOS22643.1 - 5.5 6.5 10.6 7.6 6.0 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) AIF_C PF14721.1 KOS22643.1 - 7 6.9 15.2 14 5.9 10.5 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Spc7_N PF15402.1 KOS22643.1 - 7.2 4.4 20.5 11 3.9 14.2 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Neur_chan_memb PF02932.11 KOS22643.1 - 7.4 6.3 9.9 12 5.6 6.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CPSF100_C PF13299.1 KOS22643.1 - 7.5 6.7 13.7 11 6.1 9.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AAA_23 PF13476.1 KOS22643.1 - 9.2 6.5 19.4 11 6.2 13.0 1.4 2 0 0 2 2 1 0 AAA domain SpoVR PF04293.8 KOS22643.1 - 9.3 4.4 14.8 13 4.0 10.2 1.1 1 0 0 1 1 1 0 SpoVR like protein Peptidase_S49_N PF08496.5 KOS22643.1 - 9.4 6.0 13.7 19 5.0 9.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-DHHC PF01529.15 KOS22643.1 - 9.4 5.5 11.1 2.4 7.5 4.9 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase Sec62 PF03839.11 KOS22643.1 - 9.9 5.5 9.2 18 4.6 6.4 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Sugar_tr PF00083.19 KOS22644.1 - 6.2e-79 265.6 8.5 1.3e-43 149.2 3.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KOS22644.1 - 1.8e-29 102.6 12.0 1.8e-29 102.6 8.3 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily SelP_N PF04592.9 KOS22644.1 - 0.88 8.9 4.9 1.3 8.3 3.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CDC45 PF02724.9 KOS22644.1 - 4.8 5.0 7.3 6.8 4.5 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 KOS22644.1 - 8.3 5.8 6.6 12 5.3 4.6 1.1 1 0 0 1 1 1 0 PPP4R2 Aminotran_4 PF01063.14 KOS22645.1 - 8.6e-25 87.5 0.0 1.2e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV CTP_transf_2 PF01467.21 KOS22646.1 - 0.0015 18.5 0.2 1.9 8.4 0.0 3.0 3 0 0 3 3 3 2 Cytidylyltransferase YjzC PF14168.1 KOS22646.1 - 0.084 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 YjzC-like protein CTP_transf_2 PF01467.21 KOS22647.1 - 3.2e-09 37.0 0.1 3.9e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase His_Phos_1 PF00300.17 KOS22648.1 - 1.9e-15 57.3 0.0 3.1e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_S24e PF01282.14 KOS22649.1 - 2.5e-33 113.6 0.0 4.1e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Methyltransf_16 PF10294.4 KOS22650.1 - 3.2e-17 62.5 0.0 5.5e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KOS22650.1 - 2e-06 28.3 0.2 5.5e-06 26.9 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KOS22650.1 - 0.00025 20.4 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 KOS22650.1 - 0.00056 19.5 0.0 0.00089 18.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 KOS22650.1 - 0.0015 17.7 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 KOS22650.1 - 0.0074 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PCMT PF01135.14 KOS22650.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KOS22650.1 - 0.016 15.2 0.9 0.03 14.3 0.6 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KOS22650.1 - 0.049 13.3 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF1308 PF07000.6 KOS22651.1 - 4.5e-33 114.3 0.0 1.2e-32 113.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) PKD_channel PF08016.7 KOS22653.1 - 1.5 7.1 21.5 49 2.1 14.7 2.1 1 1 0 1 1 1 0 Polycystin cation channel NRDE-2 PF08424.5 KOS22655.1 - 0.0022 16.9 0.1 0.0044 15.9 0.1 1.4 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference Macro PF01661.16 KOS22656.1 - 1.2e-06 28.3 0.0 5.8e-06 26.2 0.0 2.0 2 1 0 2 2 2 1 Macro domain TPR_11 PF13414.1 KOS22657.1 - 7.7e-12 44.6 3.9 3.8e-09 36.0 0.0 4.7 4 1 1 5 5 5 2 TPR repeat TPR_16 PF13432.1 KOS22657.1 - 2.2e-08 34.5 0.5 2.2e-08 34.5 0.3 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KOS22657.1 - 4.9e-08 32.2 9.6 0.016 15.0 0.0 5.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 KOS22657.1 - 7.4e-08 31.6 0.5 0.072 12.7 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KOS22657.1 - 4.9e-05 22.8 1.4 2 8.4 0.0 4.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KOS22657.1 - 5.7e-05 23.3 16.8 0.048 14.2 0.2 6.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KOS22657.1 - 7.6e-05 22.5 10.2 0.0026 17.6 0.1 4.6 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 KOS22657.1 - 0.00021 21.5 1.4 0.031 14.5 0.0 3.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KOS22657.1 - 0.00056 19.7 0.3 0.00056 19.7 0.2 3.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS22657.1 - 0.0054 16.4 1.6 3.3 7.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat RXT2_N PF08595.6 KOS22657.1 - 9.7 5.9 11.9 37 4.0 1.1 3.4 3 0 0 3 3 3 0 RXT2-like, N-terminal ABC_tran PF00005.22 KOS22658.1 - 5.2e-46 156.3 0.4 2.5e-23 82.8 0.0 4.0 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 KOS22658.1 - 1.4e-17 64.6 0.1 0.00063 19.7 0.0 4.4 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 KOS22658.1 - 2e-16 59.8 0.1 1.1e-05 24.8 0.0 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KOS22658.1 - 7.8e-11 42.6 1.9 4.6e-05 23.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KOS22658.1 - 1.7e-09 37.0 0.0 0.0013 18.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KOS22658.1 - 4e-09 37.3 0.0 0.00041 21.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KOS22658.1 - 8.7e-09 35.6 0.0 6.3e-05 23.1 0.0 3.3 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KOS22658.1 - 1e-07 31.2 0.0 0.00085 18.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 KOS22658.1 - 2.9e-07 30.2 0.1 0.078 12.4 0.0 3.7 4 0 0 4 4 3 2 AAA-like domain AAA_33 PF13671.1 KOS22658.1 - 4.2e-07 29.9 0.0 0.045 13.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KOS22658.1 - 1.4e-06 28.2 0.0 0.014 15.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 KOS22658.1 - 1.5e-06 28.2 0.0 0.033 14.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KOS22658.1 - 2.5e-06 27.7 0.0 0.41 10.8 0.0 4.3 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 KOS22658.1 - 2.8e-06 27.2 0.0 0.00055 19.7 0.0 2.7 2 0 0 2 2 2 1 Dynamin family MobB PF03205.9 KOS22658.1 - 6.7e-06 25.8 0.0 0.087 12.5 0.0 3.1 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KOS22658.1 - 7.1e-06 26.5 0.0 0.029 14.8 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein ArgK PF03308.11 KOS22658.1 - 7.6e-06 24.8 0.9 0.064 12.0 0.0 2.8 3 0 0 3 3 3 2 ArgK protein SbcCD_C PF13558.1 KOS22658.1 - 2e-05 24.4 0.0 0.04 13.8 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KOS22658.1 - 2.4e-05 24.6 2.0 0.42 10.9 0.0 4.1 5 0 0 5 5 3 2 AAA domain RNA_helicase PF00910.17 KOS22658.1 - 2.8e-05 24.2 0.0 0.28 11.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_15 PF13175.1 KOS22658.1 - 5.9e-05 22.2 11.3 0.11 11.5 0.0 5.2 4 2 2 6 6 6 1 AAA ATPase domain cobW PF02492.14 KOS22658.1 - 0.00013 21.5 0.2 0.27 10.6 0.0 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KOS22658.1 - 0.00014 21.5 0.0 0.094 12.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KOS22658.1 - 0.00015 21.7 0.2 1.1 9.1 0.0 4.0 4 0 0 4 4 4 1 AAA ATPase domain PduV-EutP PF10662.4 KOS22658.1 - 0.00017 21.1 0.1 0.38 10.2 0.0 3.3 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 KOS22658.1 - 0.00022 21.1 0.1 0.28 10.9 0.0 3.6 4 0 0 4 4 3 1 Domain of unknown function DUF87 AAA_14 PF13173.1 KOS22658.1 - 0.00022 21.0 0.0 1.4 8.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 KOS22658.1 - 0.00024 20.9 0.0 0.57 9.8 0.0 2.9 2 0 0 2 2 2 2 Archaeal ATPase AAA_25 PF13481.1 KOS22658.1 - 0.00032 20.1 0.0 0.37 10.1 0.0 3.2 4 0 0 4 4 3 1 AAA domain HEAT_2 PF13646.1 KOS22658.1 - 0.00033 20.8 2.3 0.99 9.7 1.9 2.8 1 1 1 2 2 2 1 HEAT repeats AAA_13 PF13166.1 KOS22658.1 - 0.00087 17.8 1.9 1.3 7.4 0.0 3.8 4 1 0 4 4 4 1 AAA domain Septin PF00735.13 KOS22658.1 - 0.0014 17.7 0.3 0.5 9.3 0.0 3.1 3 0 0 3 3 3 1 Septin MutS_V PF00488.16 KOS22658.1 - 0.0036 16.7 0.0 0.75 9.1 0.0 2.6 2 0 0 2 2 2 1 MutS domain V CLASP_N PF12348.3 KOS22658.1 - 0.004 16.5 0.5 0.23 10.7 0.1 2.6 2 1 0 2 2 2 1 CLASP N terminal HEAT PF02985.17 KOS22658.1 - 0.0042 17.0 0.2 16 5.9 0.1 4.0 3 0 0 3 3 3 0 HEAT repeat AAA_30 PF13604.1 KOS22658.1 - 0.0085 15.6 0.0 6.1 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 KOS22658.1 - 0.014 14.8 0.0 4.2 6.8 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain HEAT_EZ PF13513.1 KOS22658.1 - 0.016 15.6 1.0 15 6.1 0.0 4.6 4 1 1 5 5 3 0 HEAT-like repeat ATP_bind_1 PF03029.12 KOS22658.1 - 0.019 14.5 0.6 7.8 5.9 0.0 3.2 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 KOS22658.1 - 0.032 13.7 0.2 5 6.5 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family ParcG PF10274.4 KOS22658.1 - 0.048 13.5 0.7 9.1 6.1 0.0 3.0 2 1 1 3 3 3 0 Parkin co-regulated protein T2SE PF00437.15 KOS22658.1 - 0.058 12.2 0.1 5.1 5.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 KOS22658.1 - 0.061 12.7 0.0 14 5.0 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF815 PF05673.8 KOS22658.1 - 0.062 12.2 0.0 9.7 5.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 KOS22658.1 - 0.073 12.8 0.0 4 7.2 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain Herpes_ICP4_N PF03584.10 KOS22658.1 - 0.092 12.2 0.2 0.25 10.8 0.1 1.7 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region Serinc PF03348.10 KOS22659.1 - 0.17 10.5 1.1 0.21 10.2 0.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) NVEALA PF14055.1 KOS22659.1 - 0.58 9.9 2.4 1.5 8.5 1.6 1.8 1 1 0 1 1 1 0 NVEALA protein Peptidase_A24 PF01478.13 KOS22659.1 - 5.2 7.2 11.7 10 6.3 8.1 1.4 1 1 0 1 1 1 0 Type IV leader peptidase family GYF PF02213.11 KOS22660.1 - 8.8e-20 70.0 0.1 2.1e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 GYF domain Ycf1 PF05758.7 KOS22660.1 - 0.017 12.8 5.8 0.029 12.1 4.0 1.3 1 0 0 1 1 1 0 Ycf1 zf-DHHC PF01529.15 KOS22660.1 - 0.32 10.3 3.1 0.68 9.3 2.2 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase SPX PF03105.14 KOS22660.1 - 0.33 10.7 19.5 3.7 7.2 9.4 2.8 2 0 0 2 2 2 0 SPX domain PBP1_TM PF14812.1 KOS22660.1 - 7.4 6.9 7.9 39 4.6 5.5 2.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal eIF-3_zeta PF05091.7 KOS22660.1 - 9 4.7 22.3 20 3.6 15.4 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Abhydrolase_3 PF07859.8 KOS22661.1 - 4.1e-41 140.8 0.0 5.7e-40 137.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KOS22661.1 - 1e-06 27.6 0.0 5.5e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KOS22661.1 - 5.8e-05 22.8 0.0 0.00021 21.0 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Pex14_N PF04695.8 KOS22662.1 - 2.8e-30 105.1 0.9 2.8e-30 105.1 0.6 4.0 2 2 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region ERM PF00769.14 KOS22662.1 - 1.6e-05 24.5 1.3 1.6e-05 24.5 0.9 1.6 2 0 0 2 2 2 1 Ezrin/radixin/moesin family HLH PF00010.21 KOS22662.1 - 0.00042 19.9 3.7 3.9 7.2 0.1 3.4 1 1 2 3 3 3 2 Helix-loop-helix DNA-binding domain zf-C4H2 PF10146.4 KOS22662.1 - 0.001 19.1 5.8 0.0019 18.3 4.0 1.5 1 1 0 1 1 1 1 Zinc finger-containing protein IncA PF04156.9 KOS22662.1 - 0.0015 18.1 0.3 0.0024 17.5 0.2 1.3 1 0 0 1 1 1 1 IncA protein DUF848 PF05852.6 KOS22662.1 - 0.011 15.5 6.6 0.018 14.8 4.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) CHDCT2 PF08074.6 KOS22662.1 - 0.038 13.7 0.3 0.081 12.6 0.2 1.5 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain NPV_P10 PF05531.7 KOS22662.1 - 0.07 13.3 5.6 0.077 13.2 0.4 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.6 KOS22662.1 - 0.11 10.0 3.1 0.14 9.6 2.1 1.1 1 0 0 1 1 1 0 Prominin tRNA-synt_His PF13393.1 KOS22662.1 - 0.14 11.1 0.7 0.73 8.8 0.0 1.9 1 1 1 2 2 2 0 Histidyl-tRNA synthetase DUF3584 PF12128.3 KOS22662.1 - 0.2 8.9 10.2 0.26 8.5 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.7 KOS22662.1 - 0.2 11.4 7.9 2.2 8.1 5.3 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 KOS22662.1 - 0.84 8.2 11.1 1.2 7.6 7.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Spectrin PF00435.16 KOS22662.1 - 1 9.6 8.6 11 6.3 0.3 2.4 1 1 1 2 2 2 0 Spectrin repeat DUF1664 PF07889.7 KOS22662.1 - 1.2 8.9 6.7 2.8 7.7 4.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Ndc80_HEC PF03801.8 KOS22663.1 - 5.2e-46 155.9 2.3 9.7e-46 155.1 1.6 1.4 1 0 0 1 1 1 1 HEC/Ndc80p family WASH_WAHD PF11945.3 KOS22663.1 - 0.0022 17.3 4.1 0.0025 17.1 1.7 1.9 1 1 0 1 1 1 1 WAHD domain of WASH complex DUF3582 PF12122.3 KOS22663.1 - 0.0073 16.2 0.5 0.25 11.3 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3582) ATG16 PF08614.6 KOS22663.1 - 0.11 12.2 33.3 0.53 10.0 6.9 4.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 KOS22663.1 - 0.15 11.8 48.5 0.36 10.6 9.7 4.5 2 2 2 4 4 4 0 Tropomyosin like DUF4407 PF14362.1 KOS22663.1 - 0.18 10.6 22.6 0.16 10.9 4.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.7 KOS22663.1 - 0.7 9.6 33.4 0.66 9.7 7.4 3.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein FlxA PF14282.1 KOS22663.1 - 0.92 9.4 17.2 7.8 6.5 1.0 4.5 3 1 1 4 4 4 0 FlxA-like protein GAS PF13851.1 KOS22663.1 - 1.8 7.7 39.8 0.019 14.1 7.2 3.7 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.15 KOS22663.1 - 2.2 7.3 45.0 0.38 9.7 8.0 3.5 2 1 1 3 3 3 0 Tropomyosin FliD_C PF07195.7 KOS22663.1 - 3 7.0 14.6 14 4.9 4.6 4.0 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus WXG100 PF06013.7 KOS22663.1 - 3.6 7.6 14.6 15 5.6 0.2 4.8 4 0 0 4 4 4 0 Proteins of 100 residues with WXG DUF4391 PF14335.1 KOS22663.1 - 4.1 6.7 18.7 0.026 13.8 3.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4391) DUF4510 PF14971.1 KOS22663.1 - 4.6 7.3 9.5 0.43 10.7 1.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) FliJ PF02050.11 KOS22663.1 - 6 6.9 33.1 0.033 14.2 3.6 3.9 5 1 0 5 5 3 0 Flagellar FliJ protein Prefoldin_2 PF01920.15 KOS22663.1 - 7.2 6.4 32.7 1.8 8.3 0.5 5.3 4 2 2 6 6 6 0 Prefoldin subunit Ribosomal_L7Ae PF01248.21 KOS22664.1 - 5.5e-24 83.5 0.0 7.1e-24 83.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PulG PF11773.3 KOS22664.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin Methyltransf_4 PF02390.12 KOS22665.1 - 7.7e-54 181.7 0.0 9.3e-54 181.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KOS22665.1 - 0.00015 21.7 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS22665.1 - 0.00023 21.7 0.0 0.00041 20.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 KOS22665.1 - 0.0045 16.0 0.0 0.035 13.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_31 PF13847.1 KOS22665.1 - 0.0047 16.5 0.0 0.0068 16.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS22665.1 - 0.021 15.2 0.0 0.053 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KOS22665.1 - 0.033 13.8 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KOS22665.1 - 0.037 14.3 0.0 0.071 13.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KOS22665.1 - 0.1 13.0 0.0 0.31 11.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Homoserine_dh PF00742.14 KOS22666.1 - 1.4e-51 174.7 0.0 1.8e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KOS22666.1 - 3.7e-18 66.0 0.0 6.4e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain IGPS PF00218.16 KOS22666.1 - 0.075 12.0 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase DUF4078 PF13300.1 KOS22667.1 - 6.5e-29 99.8 20.4 6.5e-29 99.8 14.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) APG6 PF04111.7 KOS22667.1 - 2.7 6.9 5.5 5.4 5.9 3.8 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 YlqD PF11068.3 KOS22667.1 - 4 7.4 8.6 1.5 8.9 3.9 1.8 2 0 0 2 2 2 0 YlqD protein bZIP_1 PF00170.16 KOS22668.1 - 2.2e-12 46.7 5.3 3.8e-12 45.9 3.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KOS22668.1 - 4.4e-06 26.4 9.3 7.5e-06 25.6 6.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper TTKRSYEDQ PF10212.4 KOS22668.1 - 0.0082 15.1 0.1 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein HalX PF08663.5 KOS22668.1 - 0.2 11.6 2.6 0.58 10.1 1.6 1.9 2 0 0 2 2 2 0 HalX domain E_Pc_C PF06752.7 KOS22668.1 - 0.4 10.1 4.2 2.8 7.3 0.7 2.1 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus Sec7_N PF12783.2 KOS22669.1 - 1.3e-36 125.6 6.8 2e-33 115.2 0.0 5.0 5 0 0 5 5 5 3 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KOS22669.1 - 0.00018 20.9 0.0 0.0031 17.0 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) SEO_C PF14577.1 KOS22669.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Sieve element occlusion C-terminus Pribosyltran_N PF13793.1 KOS22670.1 - 2.8e-42 143.1 0.5 2.9e-41 139.8 0.0 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KOS22670.1 - 7e-39 133.4 1.1 2.9e-31 108.6 0.3 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KOS22670.1 - 2.2e-11 43.5 0.1 5e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KOS22670.1 - 0.0025 17.0 0.1 0.0041 16.3 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Thiolase_N PF00108.18 KOS22670.1 - 0.054 12.4 0.4 0.089 11.7 0.3 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain PMI_typeI PF01238.16 KOS22672.1 - 1.6e-131 438.7 0.0 1.8e-131 438.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 KOS22672.1 - 0.0045 16.6 0.0 0.49 10.0 0.0 2.6 2 0 0 2 2 2 2 AraC-like ligand binding domain Glu-tRNAGln PF02686.10 KOS22675.1 - 1.1e-05 25.1 0.4 9.5e-05 22.1 0.3 2.2 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SOCS_box PF07525.11 KOS22675.1 - 0.58 10.0 12.9 0.067 13.0 2.3 3.0 3 0 0 3 3 3 0 SOCS box PPI_Ypi1 PF07491.6 KOS22676.1 - 6.6e-22 76.9 8.7 8.8e-21 73.2 6.1 2.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor Nop14 PF04147.7 KOS22676.1 - 0.034 12.0 1.0 0.039 11.8 0.7 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 KOS22676.1 - 0.058 13.0 4.5 0.092 12.4 3.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ran_BP1 PF00638.13 KOS22677.1 - 3.6e-15 56.0 0.0 7.7e-15 55.0 0.0 1.5 1 1 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 KOS22677.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 WH1 domain Tubulin PF00091.20 KOS22678.1 - 3.6e-72 242.7 0.0 4.9e-72 242.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KOS22678.1 - 3e-46 156.5 0.7 4.6e-46 155.9 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KOS22678.1 - 5.4e-08 32.8 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain UPF0160 PF03690.8 KOS22679.1 - 1.3e-114 382.9 0.0 1.5e-114 382.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Endosulfine PF04667.12 KOS22680.1 - 7.8e-17 61.0 0.3 2.1e-16 59.6 0.2 1.8 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region MMR_HSR1 PF01926.18 KOS22681.1 - 1.7e-05 24.7 0.0 5.4e-05 23.1 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase L51_S25_CI-B8 PF05047.11 KOS22682.1 - 1.3e-18 66.4 0.4 2.4e-18 65.5 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HECT PF00632.20 KOS22683.1 - 5.4e-59 199.9 0.0 5.9e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Fungal_trans PF04082.13 KOS22685.1 - 3.9e-25 88.2 0.0 7.3e-25 87.3 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_7 PF13508.1 KOS22686.1 - 2.1e-09 37.3 0.0 3.5e-09 36.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS22686.1 - 1.4e-06 28.1 0.7 3.8e-06 26.8 0.5 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KOS22686.1 - 1.8e-06 28.0 0.3 5.1e-05 23.3 0.0 2.2 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KOS22686.1 - 0.00047 19.8 0.0 0.0014 18.3 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Ribosomal_L6 PF00347.18 KOS22687.1 - 1.9e-18 66.6 0.0 1.3e-09 38.4 0.0 2.8 2 1 0 2 2 2 2 Ribosomal protein L6 Tubulin PF00091.20 KOS22688.1 - 8.7e-69 231.6 0.0 1.5e-68 230.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KOS22688.1 - 5.7e-49 165.3 0.1 9.3e-49 164.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KOS22688.1 - 3.2e-06 27.1 0.0 8.2e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KOS22688.1 - 0.0048 16.3 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain ABC_tran PF00005.22 KOS22689.1 - 1.5e-47 161.3 0.1 4.1e-22 78.9 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 KOS22689.1 - 3.5e-21 74.8 7.0 3.5e-21 74.8 4.9 3.0 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 KOS22689.1 - 7.7e-17 62.1 0.3 0.0008 19.4 0.0 4.4 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 KOS22689.1 - 2.2e-10 40.1 1.4 0.022 13.9 0.0 4.6 5 0 0 5 5 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KOS22689.1 - 1.6e-09 38.6 0.1 0.0027 18.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 KOS22689.1 - 1.1e-06 28.6 0.0 0.004 17.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 KOS22689.1 - 1.1e-06 28.0 0.2 0.013 15.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KOS22689.1 - 3.1e-06 26.5 2.1 0.57 9.1 0.0 4.3 4 1 0 4 4 4 2 AAA ATPase domain ArgK PF03308.11 KOS22689.1 - 8.7e-06 24.6 0.2 0.097 11.4 0.0 2.5 2 0 0 2 2 2 2 ArgK protein Miro PF08477.8 KOS22689.1 - 9.9e-06 26.0 0.0 0.087 13.3 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 KOS22689.1 - 1.1e-05 24.6 0.0 0.016 14.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 KOS22689.1 - 2.8e-05 23.8 0.0 0.33 10.6 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KOS22689.1 - 2.9e-05 23.9 0.0 0.11 12.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KOS22689.1 - 4.4e-05 23.7 5.1 0.071 13.4 0.0 3.3 4 1 0 4 4 2 2 AAA domain AAA_22 PF13401.1 KOS22689.1 - 5.9e-05 23.2 0.3 0.53 10.4 0.0 3.5 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 KOS22689.1 - 7.6e-05 22.7 1.9 0.027 14.4 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.1 KOS22689.1 - 8.8e-05 22.3 0.4 0.3 11.0 0.3 3.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KOS22689.1 - 0.00014 22.2 15.5 0.007 16.7 0.1 4.2 5 0 0 5 5 4 2 AAA domain AAA PF00004.24 KOS22689.1 - 0.00023 21.3 0.0 0.82 9.8 0.0 3.3 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KOS22689.1 - 0.00043 20.2 2.1 0.2 11.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 KOS22689.1 - 0.00069 19.5 0.1 1.7 8.5 0.0 3.3 4 0 0 4 4 2 1 AAA domain NACHT PF05729.7 KOS22689.1 - 0.00085 19.0 0.0 1.4 8.5 0.0 2.7 2 0 0 2 2 2 2 NACHT domain ATP-synt_ab PF00006.20 KOS22689.1 - 0.0025 17.3 0.0 0.4 10.1 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 KOS22689.1 - 0.0037 16.9 0.0 0.67 9.6 0.0 2.6 2 0 0 2 2 2 1 NTPase cobW PF02492.14 KOS22689.1 - 0.0043 16.5 0.5 1.6 8.1 0.3 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 KOS22689.1 - 0.0062 15.9 0.0 3.7 6.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KOS22689.1 - 0.0073 15.7 0.2 2.6 7.4 0.0 2.8 2 1 0 2 2 2 1 AAA-like domain RNA_helicase PF00910.17 KOS22689.1 - 0.011 15.8 0.0 6.7 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 KOS22689.1 - 0.013 15.2 6.1 0.84 9.4 0.0 3.7 4 1 0 4 4 4 0 Dynamin family NB-ARC PF00931.17 KOS22689.1 - 0.025 13.4 0.0 6.1 5.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 KOS22689.1 - 0.044 13.4 0.3 5.2 6.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.22 KOS22689.1 - 0.052 12.9 0.8 12 5.2 0.0 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KOS22689.1 - 0.077 12.4 0.0 14 5.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KOS22689.1 - 0.13 11.7 0.6 16 4.9 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 KOS22689.1 - 1.8 8.3 9.0 2.1 8.1 0.0 3.6 4 0 0 4 4 3 0 Domain of unknown function DUF87 Fe-ADH PF00465.14 KOS22693.1 - 1e-35 123.1 0.0 1.3e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KOS22693.1 - 2.2e-12 46.7 0.0 3.4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 KOS22693.1 - 0.00012 21.6 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein MR_MLE_C PF13378.1 KOS22694.1 - 4e-18 65.4 0.0 3.1e-17 62.5 0.0 2.4 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KOS22694.1 - 1.1e-12 48.2 0.1 3.4e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KOS22694.1 - 0.00022 21.1 0.1 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 KOS22694.1 - 0.03 13.2 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Abhydrolase_2 PF02230.11 KOS22695.1 - 1.3e-28 99.9 0.0 3.1e-18 66.0 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KOS22695.1 - 6.4e-12 45.8 10.5 1e-11 45.1 7.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS22695.1 - 1.9e-10 40.6 0.1 3.2e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS22695.1 - 3.2e-07 29.7 2.9 6e-06 25.6 0.0 2.7 1 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KOS22695.1 - 0.00026 20.6 0.5 0.00083 18.9 0.4 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 KOS22695.1 - 0.0065 15.9 0.0 0.018 14.5 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 KOS22695.1 - 0.04 13.2 0.0 0.081 12.1 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family LIP PF03583.9 KOS22695.1 - 0.06 12.5 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase DUF957 PF06117.6 KOS22695.1 - 0.073 12.6 0.3 0.13 11.7 0.2 1.3 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) Mannosyl_trans2 PF04188.8 KOS22696.1 - 2.1e-61 208.1 0.3 4.1e-61 207.2 0.2 1.3 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) PMT PF02366.13 KOS22696.1 - 0.00013 21.3 4.2 0.00031 20.2 2.9 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase YTH PF04146.10 KOS22697.1 - 5.9e-11 42.1 0.0 7.4e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 YT521-B-like domain Patched PF02460.13 KOS22698.1 - 6e-78 262.6 4.3 8.4e-47 159.6 0.0 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 KOS22698.1 - 2.4e-49 166.7 3.8 2.4e-49 166.7 2.7 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KOS22698.1 - 3.7e-07 29.1 33.7 0.00029 19.6 8.6 2.5 2 1 0 2 2 2 2 MMPL family DUF4526 PF15029.1 KOS22698.1 - 0.084 12.4 1.6 0.26 10.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4526) Smr PF01713.16 KOS22699.1 - 1.4e-10 41.1 0.3 2.4e-10 40.4 0.2 1.4 1 0 0 1 1 1 1 Smr domain Rad10 PF03834.9 KOS22700.1 - 4.4e-32 109.5 0.1 7.1e-32 108.9 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 KOS22700.1 - 0.0019 18.3 0.0 0.0052 16.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain TT_ORF2 PF02957.10 KOS22700.1 - 3.2 8.4 6.8 0.21 12.3 0.4 2.0 2 0 0 2 2 2 0 TT viral ORF2 Glyco_hydro_47 PF01532.15 KOS22701.1 - 4.9e-109 364.9 0.0 5.4e-109 364.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TipAS PF07739.8 KOS22701.1 - 0.066 13.5 0.1 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain FtsJ PF01728.14 KOS22702.1 - 2.5e-60 203.5 0.0 3.4e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Proteasome PF00227.21 KOS22705.1 - 8.4e-47 158.9 0.0 1.1e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KOS22705.1 - 4.5e-09 35.4 1.1 5.3e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF3650 PF12368.3 KOS22705.1 - 0.44 10.0 3.2 0.23 10.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) Tubulin PF00091.20 KOS22706.1 - 2e-72 243.5 0.0 3.2e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KOS22706.1 - 4.8e-45 152.6 0.2 8.2e-45 151.9 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KOS22706.1 - 1e-07 32.0 0.0 2.2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KOS22706.1 - 0.031 13.7 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain PRESAN PF09687.5 KOS22706.1 - 0.073 13.1 0.4 0.073 13.1 0.2 2.2 3 0 0 3 3 3 0 Plasmodium RESA N-terminal IFRD PF05004.8 KOS22707.1 - 3.7e-19 68.9 0.0 4.4e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.1 KOS22707.1 - 0.05 14.1 2.1 10 6.7 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat FAD_binding_4 PF01565.18 KOS22708.1 - 1.6e-15 56.7 0.5 6.2e-15 54.8 0.2 2.1 3 0 0 3 3 3 1 FAD binding domain UPF0546 PF10639.4 KOS22709.1 - 1.8e-34 117.9 0.2 2.3e-34 117.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 KOS22709.1 - 0.00078 19.4 5.9 0.0053 16.7 4.1 2.1 1 1 0 1 1 1 1 EamA-like transporter family DUF1211 PF06736.6 KOS22709.1 - 0.061 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) EmrE PF13536.1 KOS22709.1 - 0.15 12.2 5.0 0.047 13.8 1.7 1.6 2 0 0 2 2 2 0 Multidrug resistance efflux transporter WD40 PF00400.27 KOS22710.1 - 1.4e-47 157.9 20.9 6.2e-11 41.7 0.1 7.3 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 KOS22710.1 - 9.9e-09 33.8 2.5 0.15 10.1 0.0 4.9 4 1 1 5 5 5 4 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 KOS22710.1 - 0.00011 21.1 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region DUF3312 PF11768.3 KOS22710.1 - 0.02 13.1 0.0 0.037 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Nbas_N PF15492.1 KOS22710.1 - 0.038 13.0 0.0 4.9 6.1 0.0 3.2 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 KOS22710.1 - 0.093 11.9 1.4 13 4.9 0.0 3.2 1 1 2 3 3 3 0 TUP1-like enhancer of split Thioesterase PF00975.15 KOS22711.1 - 3.8e-23 82.9 0.1 9.9e-23 81.5 0.1 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 KOS22711.1 - 8e-10 38.9 0.4 3.4e-09 36.9 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS22711.1 - 0.00051 19.8 0.0 0.0009 19.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KOS22711.1 - 0.0035 16.9 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.3 KOS22711.1 - 0.062 12.6 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Asp PF00026.18 KOS22712.1 - 2.3e-13 50.1 0.0 3.5e-13 49.5 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KOS22712.1 - 0.0029 17.1 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Hce2 PF14856.1 KOS22712.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor MFS_1 PF07690.11 KOS22713.1 - 7.6e-38 130.1 58.0 1.4e-34 119.3 25.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KOS22713.1 - 5.9e-07 28.2 27.9 0.0019 16.6 8.6 3.0 1 1 2 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 KOS22713.1 - 7.3e-07 28.1 26.2 1.2e-06 27.4 18.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 KOS22713.1 - 8.6e-05 22.2 5.2 0.00099 18.8 1.2 3.1 2 0 0 2 2 2 1 MFS_1 like family p450 PF00067.17 KOS22714.1 - 6.1e-44 150.2 0.0 8.6e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ESSS PF10183.4 KOS22715.1 - 1.3e-18 67.2 0.3 1.6e-18 67.0 0.2 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Acetyltransf_3 PF13302.1 KOS22716.1 - 1.3e-26 93.4 0.0 1.7e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS22716.1 - 1.3e-06 28.3 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KOS22716.1 - 1.4e-06 28.3 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KOS22716.1 - 2.1e-06 27.7 0.0 5.4e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Aminotran_4 PF01063.14 KOS22717.1 - 4.1e-30 104.9 0.0 5.7e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV MT-A70 PF05063.9 KOS22718.1 - 6e-33 113.8 0.0 8e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 KOS22718.1 - 0.017 15.1 0.0 0.048 13.6 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain p450 PF00067.17 KOS22719.1 - 2.3e-23 82.4 0.0 4.1e-23 81.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF2674 PF10879.3 KOS22719.1 - 0.12 12.1 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2674) DUF3210 PF11489.3 KOS22720.1 - 2.9e-149 499.0 72.7 2.9e-149 499.0 50.4 3.3 1 1 3 4 4 4 1 Protein of unknown function (DUF3210) Synaptobrevin PF00957.16 KOS22721.1 - 0.005 16.4 2.5 0.021 14.4 1.1 1.9 1 1 1 2 2 2 1 Synaptobrevin SNARE PF05739.14 KOS22721.1 - 0.014 15.1 0.1 0.022 14.4 0.1 1.4 1 1 0 1 1 1 0 SNARE domain DUF202 PF02656.10 KOS22721.1 - 0.046 13.9 0.1 0.046 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Rifin_STEVOR PF02009.11 KOS22721.1 - 0.046 13.3 0.2 0.048 13.3 0.1 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF912 PF06024.7 KOS22721.1 - 0.12 12.4 0.2 0.14 12.2 0.1 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) LPP PF04728.8 KOS22721.1 - 0.13 12.0 0.4 0.22 11.3 0.3 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF948 PF06103.6 KOS22721.1 - 2.6 7.9 4.4 1.1 9.2 0.1 2.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF500 PF04366.7 KOS22722.1 - 1e-24 86.3 1.4 1.7e-24 85.6 1.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KOS22722.1 - 1.4e-10 40.3 0.0 5.3e-10 38.5 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KOS22722.1 - 1.6e-10 40.3 0.0 2.7e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KOS22722.1 - 1.8e-10 40.1 0.0 3.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain gerPA PF10676.4 KOS22722.1 - 0.16 11.8 1.9 0.75 9.6 0.7 2.4 1 1 1 2 2 2 0 Spore germination protein gerPA/gerPF Rcd1 PF04078.8 KOS22723.1 - 9.3e-131 434.4 4.0 1.2e-130 434.0 2.8 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like DUF2291 PF10054.4 KOS22723.1 - 0.12 11.6 2.7 0.2 10.8 1.9 1.3 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) BAF1_ABF1 PF04684.8 KOS22723.1 - 0.21 10.3 17.9 0.28 9.9 12.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 KOS22723.1 - 2.6 6.2 14.9 3.1 5.9 10.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KOS22723.1 - 3.4 7.4 12.0 4.7 7.0 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AMP-binding PF00501.23 KOS22724.1 - 1.2e-87 294.0 0.0 1.6e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KOS22724.1 - 4.3e-14 52.0 0.0 7.8e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 KOS22724.1 - 9.8e-13 48.1 0.0 8.1e-11 42.0 0.0 2.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KOS22724.1 - 0.00058 20.7 0.2 0.004 18.0 0.0 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 KOS22725.1 - 3.1e-75 252.6 0.0 3.1e-75 252.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS22725.1 - 1.3e-40 139.1 0.0 3.8e-40 137.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KOS22725.1 - 1.8e-18 65.6 0.1 2.9e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 KOS22725.1 - 2.1e-05 23.7 0.0 4.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KOS22725.1 - 0.00015 20.8 0.0 0.00026 20.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS22725.1 - 0.0049 16.6 0.5 0.031 14.0 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KOS22725.1 - 0.01 15.2 0.0 0.027 13.8 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL WaaY PF06176.6 KOS22725.1 - 0.05 12.8 0.2 0.085 12.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) FBPase PF00316.15 KOS22726.1 - 2.8e-115 384.6 0.0 3.6e-114 380.9 0.0 1.9 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 KOS22726.1 - 0.072 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Inositol monophosphatase family DUF1604 PF07713.8 KOS22728.1 - 5.6e-39 131.8 2.3 1.6e-37 127.1 0.9 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KOS22728.1 - 1.8e-06 27.6 2.3 4.8e-06 26.2 0.6 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KOS22728.1 - 0.0041 16.9 1.1 0.0041 16.9 0.8 2.9 3 1 0 3 3 3 1 DExH-box splicing factor binding site PBP1_TM PF14812.1 KOS22728.1 - 0.31 11.3 9.2 2.2 8.6 4.6 3.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 KOS22728.1 - 4.3 6.8 6.1 0.37 10.2 0.6 1.9 2 0 0 2 2 2 0 Nucleoplasmin CIA30 PF08547.7 KOS22729.1 - 9.6e-28 97.0 0.0 1.1e-26 93.5 0.0 1.9 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) adh_short PF00106.20 KOS22730.1 - 2.7e-11 43.6 0.3 8.7e-11 42.0 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS22730.1 - 1.5e-05 24.7 0.1 2.6e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 KR domain GST_C PF00043.20 KOS22731.1 - 1.3e-07 31.5 0.1 3.2e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KOS22731.1 - 3.3e-07 30.3 0.3 1.3e-06 28.4 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KOS22731.1 - 5.1e-07 29.5 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KOS22731.1 - 7.2e-07 29.3 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KOS22731.1 - 4.7e-06 26.3 0.5 1.3e-05 25.0 0.4 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KOS22731.1 - 0.00086 19.7 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain bZIP_1 PF00170.16 KOS22732.1 - 0.00025 20.9 8.6 0.00044 20.1 6.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KOS22732.1 - 0.0013 18.5 6.5 0.0024 17.6 4.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DUF566 PF04484.7 KOS22732.1 - 0.27 10.6 17.1 0.41 10.1 11.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Striatin PF08232.7 KOS22732.1 - 0.47 10.7 7.1 0.73 10.1 4.9 1.2 1 0 0 1 1 1 0 Striatin family DUF2217 PF10265.4 KOS22732.1 - 5.5 5.6 7.4 6.7 5.3 5.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RAP1 PF07218.6 KOS22732.1 - 5.8 4.8 6.8 7.7 4.4 4.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.20 KOS22733.1 - 2.4e-70 236.6 0.0 2.9e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS22733.1 - 2.7e-31 108.5 0.0 4e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS22733.1 - 0.016 14.9 0.3 0.068 12.8 0.1 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KOS22733.1 - 0.072 12.1 0.1 0.22 10.5 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LMWPc PF01451.16 KOS22734.1 - 4.3e-36 124.2 0.0 4.9e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase PRELI PF04707.9 KOS22735.1 - 5.4e-43 146.2 0.0 6.7e-43 145.9 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family AA_permease PF00324.16 KOS22736.1 - 8.3e-116 387.1 33.8 1e-115 386.8 23.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KOS22736.1 - 2.9e-36 124.9 34.1 3.7e-36 124.5 23.6 1.1 1 0 0 1 1 1 1 Amino acid permease Hexapep PF00132.19 KOS22737.1 - 3.4e-09 35.7 7.7 2.6e-05 23.4 1.3 4.0 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KOS22737.1 - 2.5e-06 26.9 2.1 6.1e-06 25.6 0.3 2.5 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KOS22737.1 - 0.043 12.3 0.1 0.058 11.9 0.1 1.1 1 0 0 1 1 1 0 L-fucokinase DUF3455 PF11937.3 KOS22738.1 - 4e-26 92.0 0.0 6.4e-26 91.3 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) AhpC-TSA_2 PF13911.1 KOS22740.1 - 5.1e-17 61.8 0.0 1.7e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KOS22740.1 - 0.00024 20.7 0.0 0.00054 19.6 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KOS22740.1 - 0.0006 19.3 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Redoxin Peptidase_M24 PF00557.19 KOS22742.1 - 3.1e-46 157.5 0.1 4.4e-46 157.0 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Med3 PF11593.3 KOS22742.1 - 0.19 10.9 0.8 0.23 10.6 0.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PGA2 PF07543.7 KOS22742.1 - 1 9.1 4.9 3.3 7.5 3.4 1.8 1 0 0 1 1 1 0 Protein trafficking PGA2 Methyltransf_23 PF13489.1 KOS22743.1 - 2.3e-07 30.6 0.0 3.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS22743.1 - 6.3e-05 22.6 0.0 0.00019 21.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KOS22743.1 - 0.0028 17.6 0.0 0.44 10.4 0.0 2.3 2 0 0 2 2 2 2 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 KOS22743.1 - 0.013 15.9 0.0 0.051 14.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KOS22743.1 - 0.092 12.7 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_92 PF07971.7 KOS22744.1 - 7.7e-147 489.9 3.2 9.3e-147 489.6 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Trp_DMAT PF11991.3 KOS22745.1 - 4.6e-67 226.7 0.0 1.1e-66 225.5 0.0 1.6 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase dCMP_cyt_deam_1 PF00383.17 KOS22747.1 - 1.4e-26 92.0 1.8 2.1e-26 91.5 1.3 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 KOS22747.1 - 0.00041 20.6 0.1 0.0095 16.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS22747.1 - 0.0038 18.0 0.1 0.03 15.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 KOS22747.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase ThiF PF00899.16 KOS22748.1 - 3.4e-29 101.4 0.0 5.1e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KOS22748.1 - 0.18 11.8 0.0 0.47 10.5 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PIG-F PF06699.6 KOS22749.1 - 5.2e-50 170.0 1.1 5.8e-50 169.8 0.3 1.4 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F WD40 PF00400.27 KOS22750.1 - 9.9e-28 94.9 7.7 1.3e-07 31.1 0.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat 4HBT_2 PF13279.1 KOS22751.1 - 0.00085 19.7 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily GHMP_kinases_N PF00288.21 KOS22752.1 - 3.9e-12 46.0 0.0 8e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KOS22752.1 - 1.1e-05 25.5 0.0 2.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Cellulase PF00150.13 KOS22753.1 - 2.4e-44 151.6 0.0 3.1e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pax7 PF12360.3 KOS22753.1 - 0.53 10.5 4.5 0.4 10.9 0.2 2.3 2 0 0 2 2 2 0 Paired box protein 7 FAD_binding_4 PF01565.18 KOS22754.1 - 3.9e-29 100.8 0.2 6e-29 100.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pkinase PF00069.20 KOS22755.1 - 1.6e-57 194.6 0.0 1.1e-56 191.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS22755.1 - 7.3e-29 100.6 0.0 1.3e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS22755.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Zip PF02535.17 KOS22755.1 - 0.012 14.5 0.2 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 KOS22755.1 - 0.14 10.9 4.5 0.23 10.2 3.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1325 PF07039.6 KOS22756.1 - 7.2e-29 100.0 0.1 1.1e-28 99.4 0.1 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF21 PF01595.15 KOS22757.1 - 5.6e-33 113.7 0.2 8.4e-33 113.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KOS22757.1 - 2.3e-09 36.8 1.0 0.00095 18.9 0.1 3.0 3 0 0 3 3 3 2 CBS domain T4_Gp59_C PF08994.5 KOS22757.1 - 0.059 13.5 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term 2-Hacid_dh_C PF02826.14 KOS22758.1 - 1.1e-33 115.8 1.0 1e-16 60.5 0.2 2.4 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KOS22758.1 - 9.2e-32 109.3 0.0 2.1e-31 108.1 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.16 KOS22758.1 - 0.01 15.4 1.6 0.013 15.0 0.4 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 KOS22758.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.13 KOS22758.1 - 0.064 13.2 0.8 0.18 11.7 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain ACT PF01842.20 KOS22758.1 - 0.11 11.9 2.3 0.85 9.1 0.0 3.2 3 1 0 3 3 3 0 ACT domain 3HCDH_N PF02737.13 KOS22758.1 - 0.15 11.7 0.9 0.34 10.5 0.6 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3421 PF11901.3 KOS22760.1 - 5.9e-06 26.0 0.6 1.4e-05 24.7 0.1 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3421) FH2 PF02181.18 KOS22760.1 - 0.0045 15.9 2.1 0.054 12.3 0.2 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain GAS PF13851.1 KOS22760.1 - 0.29 10.3 12.1 0.34 10.0 4.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Mating_N PF12731.2 KOS22760.1 - 0.33 10.8 5.7 0.55 10.1 0.5 2.6 3 0 0 3 3 3 0 Mating-type protein beta 1 DUF745 PF05335.8 KOS22760.1 - 0.77 9.2 13.2 0.28 10.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) HALZ PF02183.13 KOS22760.1 - 0.81 9.4 5.9 3.6 7.3 0.1 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Tropomyosin PF00261.15 KOS22760.1 - 0.91 8.5 11.5 0.083 11.9 1.7 2.2 2 0 0 2 2 2 0 Tropomyosin Seryl_tRNA_N PF02403.17 KOS22760.1 - 1.2 9.1 5.6 3.8 7.5 0.1 2.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 KOS22760.1 - 2.6 6.6 8.8 6.5 5.3 5.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF607 PF04678.8 KOS22760.1 - 5.6 6.8 7.5 8.1 6.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF607 IncA PF04156.9 KOS22760.1 - 9.2 5.8 17.4 32 4.0 12.1 1.9 1 1 0 1 1 1 0 IncA protein Drf_GBD PF06371.8 KOS22761.1 - 6.1e-14 51.7 6.3 4e-09 36.1 0.0 2.9 3 1 1 4 4 4 2 Diaphanous GTPase-binding Domain Methyltransf_6 PF03737.10 KOS22762.1 - 4.9e-18 65.4 0.1 7.3e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase WWbp PF10349.4 KOS22763.1 - 4.4e-15 56.5 3.1 7.2e-15 55.8 2.1 1.3 1 0 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 KOS22763.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.5 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 KOS22763.1 - 0.041 13.4 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 GRAM domain bPH_3 PF14470.1 KOS22763.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain UCR_hinge PF02320.11 KOS22764.1 - 2.4e-25 88.2 9.1 2.4e-25 88.2 6.3 1.8 2 0 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein CDC45 PF02724.9 KOS22764.1 - 0.13 10.2 9.5 0.14 10.1 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 KOS22764.1 - 0.19 9.8 9.0 0.21 9.6 6.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HsdM_N PF12161.3 KOS22764.1 - 0.21 11.9 3.5 0.29 11.5 2.4 1.2 1 0 0 1 1 1 0 HsdM N-terminal domain CobT PF06213.7 KOS22764.1 - 0.33 10.0 16.5 0.37 9.8 11.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BSP_II PF05432.6 KOS22764.1 - 0.33 10.1 21.8 0.4 9.9 15.1 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF1682 PF07946.9 KOS22764.1 - 0.47 9.2 11.1 0.56 9.0 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Rhabdo_ncap PF00945.13 KOS22764.1 - 0.47 8.9 5.0 0.5 8.8 3.5 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Daxx PF03344.10 KOS22764.1 - 0.51 8.7 24.6 0.57 8.5 17.1 1.1 1 0 0 1 1 1 0 Daxx Family Tim54 PF11711.3 KOS22764.1 - 0.52 8.8 13.9 0.59 8.6 9.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.6 KOS22764.1 - 0.61 9.2 8.5 0.63 9.1 5.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.12 KOS22764.1 - 0.71 9.6 6.1 0.76 9.5 4.2 1.2 1 0 0 1 1 1 0 DDHD domain DUF2052 PF09747.4 KOS22764.1 - 0.88 9.4 19.7 1.2 9.0 13.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RNase_H2_suC PF08615.6 KOS22764.1 - 0.95 9.3 4.8 1.5 8.6 3.3 1.4 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF913 PF06025.7 KOS22764.1 - 1 8.0 3.8 1 8.0 2.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.11 KOS22764.1 - 1.1 8.1 14.5 1.3 8.0 10.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.7 KOS22764.1 - 1.3 8.2 18.5 1.4 8.1 12.9 1.1 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 KOS22764.1 - 1.5 8.1 19.2 1.9 7.8 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 KOS22764.1 - 1.7 6.2 14.9 1.8 6.1 10.3 1.0 1 0 0 1 1 1 0 Ycf1 Nucleoplasmin PF03066.10 KOS22764.1 - 1.9 8.0 21.4 3.5 7.1 14.8 1.5 1 0 0 1 1 1 0 Nucleoplasmin CENP-T PF15511.1 KOS22764.1 - 2.6 7.2 13.4 2.8 7.0 9.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF4045 PF13254.1 KOS22764.1 - 2.6 7.2 9.2 3 7.0 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF506 PF04720.7 KOS22764.1 - 3.1 7.3 8.2 3.9 7.0 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) DHHW PF14286.1 KOS22764.1 - 3.3 6.9 7.6 3.6 6.8 5.3 1.1 1 0 0 1 1 1 0 DHHW protein Astro_capsid PF03115.9 KOS22764.1 - 3.7 5.6 5.3 3.4 5.7 3.7 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DDRGK PF09756.4 KOS22764.1 - 3.9 6.8 23.9 5.4 6.3 16.5 1.1 1 0 0 1 1 1 0 DDRGK domain SID-1_RNA_chan PF13965.1 KOS22764.1 - 4.7 5.2 5.0 5.2 5.1 3.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 APG6 PF04111.7 KOS22764.1 - 4.7 6.1 12.8 5.1 6.0 8.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 RR_TM4-6 PF06459.7 KOS22764.1 - 4.8 6.9 21.4 5.8 6.7 14.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sporozoite_P67 PF05642.6 KOS22764.1 - 4.9 4.9 11.6 5.1 4.8 8.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 KOS22764.1 - 5.2 7.4 11.7 8.6 6.7 8.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VID27 PF08553.5 KOS22764.1 - 5.4 5.1 15.4 5.8 4.9 10.7 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Trypan_PARP PF05887.6 KOS22764.1 - 5.5 6.8 26.3 7.4 6.3 18.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SAPS PF04499.10 KOS22764.1 - 6.6 5.2 8.8 7.3 5.0 6.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3464 PF11947.3 KOS22764.1 - 7 6.0 6.6 11 5.4 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Nop14 PF04147.7 KOS22764.1 - 7.4 4.3 24.3 8.7 4.1 16.8 1.0 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.17 KOS22764.1 - 7.5 5.4 8.7 8.9 5.2 6.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SspB PF04386.8 KOS22764.1 - 8.4 5.9 12.1 14 5.3 8.4 1.4 1 0 0 1 1 1 0 Stringent starvation protein B Neur_chan_memb PF02932.11 KOS22764.1 - 8.8 6.1 7.5 11 5.8 5.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PBP1_TM PF14812.1 KOS22765.1 - 0.044 14.0 10.3 0.071 13.4 7.1 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 KOS22765.1 - 0.13 10.2 0.2 0.15 10.0 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein M_domain PF12938.2 KOS22765.1 - 0.42 10.3 2.8 0.69 9.6 1.9 1.2 1 0 0 1 1 1 0 M domain of GW182 Nucleo_P87 PF07267.6 KOS22765.1 - 0.76 8.3 2.4 0.99 8.0 1.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Sigma70_ner PF04546.8 KOS22765.1 - 1.7 8.1 6.5 2.5 7.6 4.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 KOS22765.1 - 6 4.6 6.4 8.1 4.2 4.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4611 PF15387.1 KOS22765.1 - 8.6 6.5 9.2 23 5.2 6.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Methyltransf_26 PF13659.1 KOS22767.1 - 4.3 7.3 10.2 59 3.7 6.9 2.8 1 1 0 1 1 1 0 Methyltransferase domain Aminotran_1_2 PF00155.16 KOS22768.1 - 2.5e-94 316.2 0.0 2.8e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RasGEF PF00617.14 KOS22769.1 - 3.3e-50 170.4 0.0 4.4e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 RasGEF domain LdpA_C PF12617.3 KOS22769.1 - 0.084 12.1 1.0 0.14 11.4 0.7 1.3 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal Baculo_PEP_C PF04513.7 KOS22770.1 - 0.00056 19.7 3.2 0.008 16.0 0.1 2.5 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF975 PF06161.6 KOS22770.1 - 2.5 7.7 7.1 3 7.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF975) Trp_syntA PF00290.15 KOS22771.1 - 3.8e-90 300.9 0.0 6.9e-90 300.0 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KOS22771.1 - 2.5e-45 155.0 0.3 4.5e-45 154.2 0.2 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L28 PF00830.14 KOS22772.1 - 1.7e-12 46.9 0.3 2.6e-12 46.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal L28 family MFS_1 PF07690.11 KOS22773.1 - 4.7e-37 127.5 30.4 1.4e-32 112.8 14.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 KOS22773.1 - 0.071 11.7 9.2 0.026 13.2 1.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF791) LacY_symp PF01306.14 KOS22773.1 - 0.22 10.0 9.8 3.3 6.1 0.0 3.1 3 0 0 3 3 3 0 LacY proton/sugar symporter AA_permease PF00324.16 KOS22774.1 - 1.2e-130 436.0 29.5 1.5e-130 435.7 20.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KOS22774.1 - 9.1e-35 120.0 32.1 1.1e-34 119.7 22.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1741 PF08427.5 KOS22775.1 - 2.6e-81 272.5 0.1 8e-81 270.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) MFS_1 PF07690.11 KOS22776.1 - 3.6e-18 65.4 32.7 6.3e-18 64.6 22.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KOS22776.1 - 1.7e-09 37.3 5.2 1.7e-09 37.3 3.6 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 CN_hydrolase PF00795.17 KOS22777.1 - 1.4e-27 96.3 0.1 4.8e-27 94.5 0.0 1.8 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Acyl-CoA_dh_1 PF00441.19 KOS22778.1 - 1.6e-31 109.4 3.2 2.6e-31 108.7 2.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KOS22778.1 - 1.2e-19 69.8 0.1 2.7e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KOS22778.1 - 1.1e-17 63.2 0.5 1.9e-17 62.5 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KOS22778.1 - 1.3e-05 25.4 0.8 2.8e-05 24.3 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KOS22778.1 - 0.00011 22.8 0.0 0.00024 21.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain zf-CCHC PF00098.18 KOS22779.1 - 3.2e-51 168.9 63.2 2e-08 33.7 2.7 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KOS22779.1 - 4.1e-14 51.9 44.4 0.0034 17.0 0.3 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.1 KOS22779.1 - 5.3e-09 35.5 46.2 0.028 14.1 0.7 6.7 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 KOS22779.1 - 1.4e-07 31.1 50.5 0.09 12.5 1.4 7.1 2 2 5 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.1 KOS22779.1 - 0.018 14.5 1.0 0.018 14.5 0.7 6.6 3 2 4 7 7 7 0 Zinc knuckle Yae1_N PF09811.4 KOS22780.1 - 5.7e-07 28.9 2.0 1e-06 28.1 1.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF2360 PF10152.4 KOS22780.1 - 0.013 15.7 0.1 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF4349 PF14257.1 KOS22780.1 - 0.035 13.3 0.6 0.05 12.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) tRNA-synt_1g PF09334.6 KOS22781.1 - 1.7e-143 478.0 0.0 2.4e-143 477.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KOS22781.1 - 3.4e-07 28.6 0.0 0.0036 15.3 0.0 3.6 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KOS22781.1 - 0.0001 22.0 0.6 0.00021 21.0 0.4 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Med19 PF10278.4 KOS22781.1 - 0.067 12.8 3.1 0.14 11.8 2.1 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNase_H2-Ydr279 PF09468.5 KOS22781.1 - 0.075 12.2 2.4 0.13 11.4 1.7 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) NARP1 PF12569.3 KOS22781.1 - 6.1 5.4 12.7 69 1.9 8.5 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 OAD_gamma PF04277.8 KOS22781.1 - 8.6 6.8 10.5 18 5.8 7.3 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AhpC-TSA PF00578.16 KOS22782.1 - 3.4e-25 88.1 0.0 7.9e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KOS22782.1 - 3.1e-15 55.9 0.0 8e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KOS22782.1 - 0.0011 18.8 0.0 0.0067 16.3 0.0 2.2 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DNA_methylase PF00145.12 KOS22782.1 - 2.4 7.1 17.7 3.2 6.7 12.2 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase LMBR1 PF04791.11 KOS22782.1 - 7.5 5.0 12.9 8.2 4.8 8.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein UCR_14kD PF02271.11 KOS22784.1 - 6.7e-41 138.3 0.5 7.6e-41 138.1 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.22 KOS22785.1 - 9e-69 227.2 0.4 1.5e-23 82.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein UCH PF00443.24 KOS22787.1 - 6.7e-42 143.4 0.0 1.5e-41 142.3 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS22787.1 - 3.5e-13 49.6 0.0 6.9e-12 45.4 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RRP7 PF12923.2 KOS22787.1 - 0.15 12.1 0.3 0.39 10.7 0.2 1.7 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Pkinase PF00069.20 KOS22788.1 - 1.8e-05 24.0 0.0 0.065 12.3 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain DUF2461 PF09365.5 KOS22789.1 - 4.9e-65 218.8 0.0 6.7e-65 218.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Voldacs PF03517.8 KOS22789.1 - 0.15 11.9 0.2 0.15 11.9 0.1 3.6 3 1 0 3 3 3 0 Regulator of volume decrease after cellular swelling Nucleoplasmin PF03066.10 KOS22789.1 - 4.5 6.7 33.3 0.6 9.6 3.8 3.3 3 0 0 3 3 3 0 Nucleoplasmin CTP_transf_2 PF01467.21 KOS22790.1 - 8.9e-14 51.8 0.0 1.2e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase HSP70 PF00012.15 KOS22791.1 - 1.2e-266 885.5 13.5 1.3e-266 885.3 9.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KOS22791.1 - 1.7e-16 59.7 2.0 1.7e-15 56.4 0.4 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 KOS22791.1 - 0.0021 16.9 0.7 0.053 12.3 0.1 2.7 2 1 1 3 3 3 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 KOS22791.1 - 0.028 13.5 0.3 0.028 13.5 0.2 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase SicP-binding PF09119.5 KOS22791.1 - 0.062 13.0 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 SicP binding WD40 PF00400.27 KOS22792.1 - 2.1e-18 65.4 1.3 6.1e-06 25.9 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat EIF_2_alpha PF07541.7 KOS22793.1 - 6e-38 129.0 0.0 1.2e-37 128.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KOS22793.1 - 1.5e-12 47.4 0.8 3.3e-12 46.3 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DUF2361 PF10153.4 KOS22793.1 - 0.039 14.1 0.8 0.063 13.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) DUF3295 PF11702.3 KOS22794.1 - 7.2e-124 414.5 35.1 8.9e-124 414.2 24.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KOS22794.1 - 1.9e-12 46.5 0.9 6e-12 44.9 0.6 2.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TPR_14 PF13428.1 KOS22795.1 - 0.72 10.6 4.9 84 4.2 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-CHY PF05495.7 KOS22796.1 - 1.6e-14 53.7 23.2 2.6e-14 53.1 8.7 3.4 3 0 0 3 3 3 2 CHY zinc finger Mu-like_Com PF10122.4 KOS22796.1 - 0.00021 20.2 0.2 0.00021 20.2 0.1 2.8 2 1 0 2 2 2 1 Mu-like prophage protein Com RWD PF05773.17 KOS22796.1 - 0.0078 16.1 1.0 0.019 14.8 0.0 2.1 2 1 0 2 2 2 1 RWD domain tRNA-synt_2 PF00152.15 KOS22797.1 - 6.4e-71 238.8 0.0 8.1e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KOS22797.1 - 0.0019 17.9 0.1 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SWIB PF02201.13 KOS22798.1 - 3.2e-12 45.9 0.0 6.1e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Mo25 PF08569.6 KOS22799.1 - 1.2e-66 225.0 4.5 1.5e-66 224.7 3.1 1.0 1 0 0 1 1 1 1 Mo25-like RepA_N PF06970.6 KOS22799.1 - 0.0087 15.8 0.5 0.02 14.6 0.1 1.8 2 0 0 2 2 2 1 Replication initiator protein A (RepA) N-terminus DUF1108 PF06531.6 KOS22799.1 - 0.084 13.0 1.1 0.87 9.7 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1108) DUF544 PF04424.8 KOS22799.1 - 0.093 12.5 0.2 0.21 11.4 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF544) SNARE PF05739.14 KOS22800.1 - 2.7e-12 46.2 3.1 4.7e-12 45.4 2.1 1.4 1 0 0 1 1 1 1 SNARE domain Med3 PF11593.3 KOS22800.1 - 0.0015 17.8 0.5 0.0018 17.6 0.3 1.3 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal AAA PF00004.24 KOS22800.1 - 0.044 13.9 0.1 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ODV-E18 PF10717.4 KOS22800.1 - 7.7 6.0 6.2 2 7.8 0.1 2.3 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Pkinase PF00069.20 KOS22801.1 - 6.1e-68 228.7 0.0 1e-67 228.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS22801.1 - 6.2e-35 120.5 0.0 2.2e-34 118.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS22801.1 - 1.9e-05 23.8 0.2 0.0028 16.6 0.0 2.8 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KOS22801.1 - 0.00036 19.6 0.0 0.00057 19.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KOS22801.1 - 0.0012 18.6 0.1 0.0027 17.4 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KOS22801.1 - 0.025 13.3 0.3 0.73 8.5 0.1 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase PPTA PF01239.17 KOS22802.1 - 1.5e-34 115.8 15.8 3.4e-09 35.6 0.3 5.5 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Glyco_hydro_18 PF00704.23 KOS22803.1 - 8.9e-102 341.0 15.1 1e-101 340.8 10.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 UbiA PF01040.13 KOS22804.1 - 4.8e-07 29.2 2.6 5.6e-07 29.0 1.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family zf-4CXXC_R1 PF10497.4 KOS22805.1 - 0.021 14.9 19.2 0.14 12.2 13.4 2.2 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 tRNA-synt_1 PF00133.17 KOS22806.1 - 7.4e-218 724.3 0.0 8.9e-217 720.8 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KOS22806.1 - 3.2e-25 88.6 0.0 7.4e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KOS22806.1 - 2e-17 62.9 0.2 9.6e-08 31.0 0.1 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KOS22806.1 - 0.0058 15.7 0.0 0.084 11.9 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain OPT PF03169.10 KOS22807.1 - 4.6e-46 157.5 22.1 4.3e-23 81.6 1.6 3.0 1 1 1 3 3 3 3 OPT oligopeptide transporter protein DUF3270 PF11674.3 KOS22807.1 - 0.019 14.9 2.0 0.023 14.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) BAF1_ABF1 PF04684.8 KOS22808.1 - 0.054 12.3 9.7 0.076 11.8 6.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor UPF0560 PF10577.4 KOS22808.1 - 0.24 9.6 11.3 0.34 9.1 7.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4410 PF14366.1 KOS22808.1 - 0.24 11.1 2.0 0.9 9.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) RasGAP PF00616.14 KOS22809.1 - 6.8e-43 146.6 0.0 6.8e-43 146.6 0.0 2.7 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KOS22809.1 - 0.0047 16.7 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain SAE2 PF08573.5 KOS22809.1 - 0.039 14.6 3.4 0.1 13.2 2.4 1.7 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus NAD_binding_2 PF03446.10 KOS22810.1 - 1.1e-36 126.1 0.2 2e-36 125.3 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KOS22810.1 - 2.2e-32 111.6 0.5 6.1e-32 110.2 0.0 2.0 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 KOS22810.1 - 2.5e-07 29.7 0.1 3.7e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 KOS22810.1 - 3e-07 30.7 0.4 1.2e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KOS22810.1 - 0.00023 21.6 0.1 0.00054 20.4 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 KOS22810.1 - 0.0046 16.9 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 KOS22810.1 - 0.033 13.9 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus KilA-N PF04383.8 KOS22811.1 - 0.0058 16.2 0.0 0.035 13.7 0.0 2.1 1 1 1 2 2 2 1 KilA-N domain RESP18 PF14948.1 KOS22811.1 - 0.27 11.2 2.3 0.94 9.5 1.6 2.0 1 0 0 1 1 1 0 RESP18 domain DLIC PF05783.6 KOS22811.1 - 1.1 7.9 5.6 1.9 7.0 3.9 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Phage_H_T_join PF05521.6 KOS22811.1 - 2.2 8.6 4.7 20 5.5 1.2 2.9 3 0 0 3 3 3 0 Phage head-tail joining protein TFIIA PF03153.8 KOS22811.1 - 2.4 7.9 10.2 3.5 7.4 7.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rho_GDI PF02115.12 KOS22812.1 - 1.7e-57 194.0 0.3 1.9e-57 193.9 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.23 KOS22813.1 - 4.8e-42 143.6 0.7 5.9e-42 143.3 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MIP-T3 PF10243.4 KOS22814.1 - 0.21 10.0 41.8 0.25 9.7 29.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TFIIF_alpha PF05793.7 KOS22814.1 - 3.1 6.0 34.1 4 5.6 23.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Fungal_trans_2 PF11951.3 KOS22815.1 - 6.6e-23 80.9 0.2 9.2e-23 80.4 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2107 PF09880.4 KOS22815.1 - 0.037 13.9 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2107) MFS_1 PF07690.11 KOS22816.1 - 1.4e-39 135.8 51.3 6.2e-39 133.7 34.8 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily ORC4_C PF14629.1 KOS22818.1 - 2.1e-40 138.3 0.0 5.4e-33 114.1 0.0 2.3 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 KOS22818.1 - 1.4e-16 61.0 0.3 7.7e-15 55.3 0.1 3.2 2 1 0 2 2 2 1 AAA ATPase domain PHD_2 PF13831.1 KOS22818.1 - 3.8e-11 42.0 1.3 3.8e-11 42.0 0.9 2.0 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KOS22818.1 - 4.5e-11 42.2 5.5 7.6e-11 41.5 3.8 1.4 1 0 0 1 1 1 1 PHD-finger AAA PF00004.24 KOS22818.1 - 2.7e-09 37.2 0.0 3.7e-08 33.6 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS22818.1 - 3.5e-09 36.9 0.0 7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KOS22818.1 - 3.5e-06 26.7 0.0 1.2e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 KOS22818.1 - 8.7e-06 25.6 0.0 1.7e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 KOS22818.1 - 0.00037 20.4 0.0 0.0008 19.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KOS22818.1 - 0.0014 17.5 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.9 KOS22818.1 - 0.0015 17.6 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_10 PF12846.2 KOS22818.1 - 0.0034 16.8 0.0 0.68 9.3 0.0 2.7 3 0 0 3 3 3 1 AAA-like domain DUF815 PF05673.8 KOS22818.1 - 0.0037 16.2 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 KOS22818.1 - 0.0068 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KOS22818.1 - 0.011 16.5 0.0 0.037 14.8 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_5 PF07728.9 KOS22818.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KOS22818.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 KOS22818.1 - 0.013 15.0 0.0 0.058 12.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KOS22818.1 - 0.013 15.1 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ATP-synt_ab PF00006.20 KOS22818.1 - 0.024 14.1 0.0 0.05 13.1 0.0 1.6 2 0 0 2 2 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Bac_DnaA PF00308.13 KOS22818.1 - 0.03 13.9 0.0 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein T2SE PF00437.15 KOS22818.1 - 0.047 12.5 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 KOS22818.1 - 0.049 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KOS22818.1 - 0.052 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 KOS22818.1 - 0.066 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KOS22818.1 - 0.07 12.9 0.2 0.58 10.0 0.0 2.4 3 0 0 3 3 2 0 AAA domain SMC_N PF02463.14 KOS22818.1 - 0.076 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.16 KOS22818.1 - 0.083 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DAP3 PF10236.4 KOS22818.1 - 0.084 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 G-alpha PF00503.15 KOS22818.1 - 0.096 11.3 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit FYVE_2 PF02318.11 KOS22818.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger MobB PF03205.9 KOS22818.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 KOS22818.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain SRP54 PF00448.17 KOS22818.1 - 0.2 11.1 0.0 0.64 9.4 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TIP49 PF06068.8 KOS22818.1 - 0.24 10.0 0.0 0.36 9.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus ODV-E18 PF10717.4 KOS22821.1 - 0.0075 15.6 1.0 0.012 14.9 0.3 1.6 2 0 0 2 2 2 1 Occlusion-derived virus envelope protein ODV-E18 ASFV_J13L PF05568.6 KOS22821.1 - 0.039 13.4 1.6 0.072 12.6 1.1 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein AJAP1_PANP_C PF15298.1 KOS22821.1 - 0.046 13.5 2.1 0.074 12.9 1.4 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus TMEM154 PF15102.1 KOS22821.1 - 0.11 12.1 0.5 0.18 11.4 0.4 1.3 1 0 0 1 1 1 0 TMEM154 protein family Shisa PF13908.1 KOS22821.1 - 0.19 11.9 6.3 0.048 13.8 2.5 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator SoxE PF06525.6 KOS22821.1 - 0.44 9.8 4.1 0.15 11.2 0.5 1.8 1 1 1 2 2 2 0 Sulfocyanin (SoxE) Rifin_STEVOR PF02009.11 KOS22821.1 - 0.85 9.2 5.8 0.34 10.4 2.3 1.5 2 0 0 2 2 2 0 Rifin/stevor family DUF929 PF06053.6 KOS22821.1 - 1.1 8.3 5.8 1.4 7.9 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF3753 PF12575.3 KOS22821.1 - 2.2 8.1 7.3 5.1 6.9 5.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Protocadherin PF08374.6 KOS22821.1 - 3.1 7.3 5.8 4 7.0 3.4 1.7 1 1 1 2 2 2 0 Protocadherin ADH_zinc_N_2 PF13602.1 KOS22822.1 - 1.6e-21 77.5 0.0 4.3e-21 76.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KOS22822.1 - 2.3e-14 53.0 0.7 4.3e-14 52.1 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KOS22822.1 - 0.0018 18.3 0.4 0.0028 17.6 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KOS22822.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ThiF PF00899.16 KOS22822.1 - 0.84 9.4 3.3 1.5 8.6 2.3 1.4 1 0 0 1 1 1 0 ThiF family PhyH PF05721.8 KOS22823.1 - 1.1e-10 41.9 0.0 4e-10 40.0 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) p450 PF00067.17 KOS22824.1 - 2.3e-25 89.0 0.0 2.8e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 KOS22825.1 - 4.7e-39 134.0 0.0 6.5e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KOS22825.1 - 2.2e-05 24.9 0.4 5.9e-05 23.6 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS22825.1 - 0.0062 16.2 0.2 0.043 13.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Rrf2 PF02082.15 KOS22825.1 - 0.035 14.2 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Methyltransf_26 PF13659.1 KOS22825.1 - 0.35 10.9 3.7 0.6 10.1 1.4 2.3 2 1 0 2 2 2 0 Methyltransferase domain p450 PF00067.17 KOS22826.1 - 7.4e-66 222.5 0.0 9e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF218 PF02698.12 KOS22827.1 - 7.1e-07 28.8 0.0 1.2e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 DUF218 domain Abhydrolase_5 PF12695.2 KOS22828.1 - 3e-10 40.0 0.0 5e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS22828.1 - 7.9e-08 32.4 9.3 1.1e-07 31.9 6.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS22828.1 - 6.6e-07 28.7 0.1 0.0029 16.8 0.2 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family PhoPQ_related PF10142.4 KOS22828.1 - 0.078 11.4 0.1 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Abhydrolase_2 PF02230.11 KOS22828.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase G-patch PF01585.18 KOS22829.1 - 3.2e-07 30.0 0.8 8.6e-07 28.6 0.1 2.0 2 0 0 2 2 2 1 G-patch domain Eapp_C PF10238.4 KOS22829.1 - 0.4 10.5 1.6 3 7.7 0.0 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein G-patch_2 PF12656.2 KOS22829.1 - 1.2 9.0 5.8 1 9.2 0.1 3.2 2 1 1 3 3 3 0 DExH-box splicing factor binding site GST_N_2 PF13409.1 KOS22832.1 - 9.3e-20 70.4 0.1 3.5e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KOS22832.1 - 9.8e-13 47.7 0.0 2e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KOS22832.1 - 4.1e-06 26.6 0.0 1.4e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KOS22832.1 - 4.8e-05 23.4 0.1 0.061 13.5 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KOS22832.1 - 0.0024 18.3 0.0 0.0069 16.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Cerato-platanin PF07249.7 KOS22834.1 - 0.014 15.3 0.1 0.052 13.5 0.1 2.0 1 1 0 1 1 1 0 Cerato-platanin GTP_cyclohydro2 PF00925.15 KOS22835.1 - 8.6e-58 194.3 0.0 5.6e-53 178.6 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II Mito_fiss_reg PF05308.6 KOS22835.1 - 7.6 5.8 9.1 12 5.2 6.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator GFA PF04828.9 KOS22838.1 - 8.3e-05 22.4 11.5 0.0029 17.5 3.9 2.5 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme NDUF_B7 PF05676.8 KOS22839.1 - 3.6e-33 112.7 4.2 4.3e-33 112.5 2.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KOS22839.1 - 0.00016 21.4 1.8 0.00016 21.4 1.3 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2267 PF10025.4 KOS22839.1 - 0.023 14.7 0.0 0.031 14.3 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Antifungal_prot PF11402.3 KOS22839.1 - 0.87 9.8 3.8 1.8 8.8 2.6 1.6 1 1 0 1 1 1 0 Antifungal protein Mito_fiss_reg PF05308.6 KOS22840.1 - 2.9 7.1 6.9 3.7 6.8 4.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DIE2_ALG10 PF04922.7 KOS22841.1 - 1.6e-67 228.2 0.2 7.1e-67 226.0 0.1 2.2 1 1 0 1 1 1 1 DIE2/ALG10 family EMP70 PF02990.11 KOS22842.1 - 2.1e-194 646.8 6.8 2.5e-194 646.6 4.7 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 KOS22842.1 - 0.021 14.9 0.0 0.021 14.9 0.0 4.2 3 2 1 4 4 4 0 NfeD-like C-terminal, partner-binding PIRT PF15099.1 KOS22842.1 - 0.13 11.4 1.0 0.32 10.2 0.7 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Sas10_Utp3 PF04000.10 KOS22843.1 - 3.9e-15 55.8 2.1 3.9e-15 55.8 1.4 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Sporozoite_P67 PF05642.6 KOS22843.1 - 0.23 9.2 2.7 0.23 9.2 0.2 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen CDV3 PF15359.1 KOS22843.1 - 0.79 9.7 11.2 0.037 14.1 3.4 1.9 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 DUF1510 PF07423.6 KOS22843.1 - 0.94 8.8 6.6 0.28 10.5 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Nucleoplasmin PF03066.10 KOS22843.1 - 2.6 7.5 8.4 0.49 9.8 2.8 1.9 2 0 0 2 2 2 0 Nucleoplasmin FAM176 PF14851.1 KOS22843.1 - 3.4 7.3 6.2 0.93 9.1 1.3 2.0 2 0 0 2 2 2 0 FAM176 family QCR10 PF09796.4 KOS22844.1 - 3.4e-15 55.4 0.0 4.3e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF4118 PF13493.1 KOS22844.1 - 0.11 12.7 0.3 0.15 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) Med4 PF10018.4 KOS22845.1 - 6.6e-36 123.4 17.8 2.2e-35 121.7 11.6 2.2 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 CCDC66 PF15236.1 KOS22845.1 - 0.008 15.8 21.4 0.008 15.8 14.8 2.3 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 66 SpoIIIAH PF12685.2 KOS22845.1 - 0.016 14.6 6.7 0.028 13.9 4.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein TFIIA PF03153.8 KOS22845.1 - 0.038 13.8 15.2 0.051 13.4 10.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRCC PF10253.4 KOS22845.1 - 0.092 13.4 11.8 0.18 12.4 8.2 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Caldesmon PF02029.10 KOS22845.1 - 1.3 7.3 21.9 2.6 6.3 15.2 1.4 1 0 0 1 1 1 0 Caldesmon Glyco_transf_15 PF01793.11 KOS22846.1 - 6.6e-142 472.3 2.1 7.7e-142 472.0 1.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.14 KOS22846.1 - 0.24 11.2 3.9 0.11 12.3 0.6 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Ribosom_S12_S23 PF00164.20 KOS22847.1 - 6.8e-41 138.5 1.0 8.5e-41 138.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Sin_N PF04801.8 KOS22848.1 - 1.1e-20 73.9 0.0 1.9e-20 73.1 0.0 1.3 1 1 0 1 1 1 1 Sin-like protein conserved region PAT1 PF09770.4 KOS22849.1 - 2.2e-183 611.6 7.7 9.8e-115 384.6 1.3 3.0 1 1 2 3 3 3 3 Topoisomerase II-associated protein PAT1 PBP1_TM PF14812.1 KOS22850.1 - 1.9 8.8 14.3 41 4.5 0.0 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2722 PF10846.3 KOS22850.1 - 3.3 6.6 6.1 3 6.7 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Ribosomal_L23 PF00276.15 KOS22851.1 - 7.8e-14 51.3 0.0 1.4e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 RyR PF02026.11 KOS22851.1 - 0.1 12.6 0.5 0.39 10.7 0.2 1.9 2 0 0 2 2 2 0 RyR domain Peptidase_S24 PF00717.18 KOS22852.1 - 6.2e-05 22.5 0.6 0.00015 21.3 0.4 1.6 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KOS22852.1 - 0.0004 19.9 0.1 0.11 12.0 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Mito_carr PF00153.22 KOS22853.1 - 6.4e-60 198.8 0.0 1.2e-19 69.8 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF383 PF04063.9 KOS22854.1 - 1.1e-67 227.3 0.0 2.5e-67 226.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KOS22854.1 - 8.3e-21 73.3 0.5 1.6e-20 72.4 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Bystin PF05291.6 KOS22855.1 - 4.8e-126 419.7 0.0 7.1e-126 419.2 0.0 1.1 1 0 0 1 1 1 1 Bystin CoA_binding_2 PF13380.1 KOS22857.1 - 1.4e-22 80.0 0.0 1.7e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain DUF1425 PF07233.7 KOS22857.1 - 0.026 14.0 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) Peptidase_M3 PF01432.15 KOS22858.1 - 9.1e-144 479.8 0.0 1.2e-143 479.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 EF-hand_7 PF13499.1 KOS22859.1 - 7.9e-13 48.3 0.1 6.3e-11 42.2 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KOS22859.1 - 1.1e-09 37.3 0.2 0.0031 17.2 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 KOS22859.1 - 4.1e-09 36.2 0.0 0.0027 17.6 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KOS22859.1 - 1.8e-08 33.8 0.0 0.00047 19.7 0.0 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KOS22859.1 - 4.8e-08 31.7 0.3 0.0053 15.9 0.0 4.1 4 1 0 4 4 4 2 EF hand UPF0154 PF03672.8 KOS22859.1 - 0.12 12.0 0.0 0.86 9.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 KOS22859.1 - 0.35 10.2 1.8 3.7 7.0 0.1 3.2 3 0 0 3 3 3 0 EF hand 7tm_1 PF00001.16 KOS22860.1 - 1e-05 24.8 5.0 1.9e-05 23.9 3.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF1049 PF06305.6 KOS22860.1 - 0.022 14.2 0.0 0.022 14.2 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) Git3 PF11710.3 KOS22860.1 - 0.024 14.2 11.4 0.044 13.3 7.9 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Ldh_1_N PF00056.18 KOS22861.1 - 4.3e-43 146.5 0.2 8.3e-42 142.3 0.0 2.1 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KOS22861.1 - 1.7e-42 145.1 0.0 2.4e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Semialdhyde_dh PF01118.19 KOS22861.1 - 0.0031 17.8 0.4 0.014 15.6 0.0 2.2 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KOS22861.1 - 0.009 14.7 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family zf-C2HC5 PF06221.8 KOS22862.1 - 5.2e-21 74.1 4.6 8.1e-21 73.5 3.2 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Ribosomal_60s PF00428.14 KOS22862.1 - 8.2 6.8 31.7 3.5 8.1 1.3 4.9 4 0 0 4 4 4 0 60s Acidic ribosomal protein SLAC1 PF03595.12 KOS22863.1 - 3.9e-78 262.4 41.0 4.3e-78 262.2 28.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Hydrolase PF00702.21 KOS22864.1 - 4.5e-23 82.7 0.0 1.7e-22 80.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KOS22864.1 - 1.3e-20 74.3 0.1 3.1e-20 73.1 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KOS22864.1 - 1.1e-18 67.1 0.4 4.1e-18 65.2 0.0 2.1 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KOS22864.1 - 0.0012 18.7 0.6 0.003 17.4 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF4059 PF13268.1 KOS22864.1 - 0.041 14.0 0.5 4.2 7.6 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) Hydrolase_3 PF08282.7 KOS22864.1 - 0.049 13.2 2.9 0.16 11.5 0.0 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase DUF4363 PF14276.1 KOS22864.1 - 0.12 12.0 0.4 14 5.4 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Pro-kuma_activ PF09286.6 KOS22865.1 - 2e-18 66.8 0.0 7.7e-18 64.9 0.0 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KOS22865.1 - 9.3e-09 34.8 0.1 1.5e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Subtilase family SIR2 PF02146.12 KOS22866.1 - 2e-32 112.3 0.2 2.7e-10 40.2 0.0 3.4 3 0 0 3 3 3 3 Sir2 family SKI PF01202.17 KOS22866.1 - 0.022 14.6 2.1 0.045 13.6 0.0 2.2 1 1 1 2 2 2 0 Shikimate kinase Nucleoplasmin PF03066.10 KOS22866.1 - 0.39 10.2 15.4 0.86 9.1 10.7 1.6 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 KOS22866.1 - 3.8 5.4 19.9 0.056 11.4 8.2 1.9 2 0 0 2 2 2 0 CDC45-like protein Whi5 PF08528.6 KOS22867.1 - 3.4e-05 23.3 0.0 5.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Chorion_2 PF03964.10 KOS22869.1 - 0.13 12.7 0.3 0.13 12.7 0.2 2.1 2 0 0 2 2 2 0 Chorion family 2 Aminotran_5 PF00266.14 KOS22870.1 - 4.3e-24 84.9 0.0 5.7e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.14 KOS22870.1 - 0.00017 20.1 0.0 0.00026 19.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Alginate_lyase2 PF08787.6 KOS22871.1 - 1.8e-47 161.9 0.0 2e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Voltage_CLC PF00654.15 KOS22872.1 - 3.9e-83 279.3 18.1 3.9e-83 279.3 12.6 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel LacI PF00356.16 KOS22872.1 - 0.69 9.5 5.2 0.8 9.3 0.2 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Glyco_hydro_cc PF11790.3 KOS22873.1 - 1e-37 129.8 0.1 1.1e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fip1 PF05182.8 KOS22873.1 - 0.052 12.8 0.4 0.097 11.9 0.3 1.4 1 0 0 1 1 1 0 Fip1 motif SAC3_GANP PF03399.11 KOS22875.1 - 7.8e-66 221.5 0.2 1e-65 221.1 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KOS22875.1 - 0.0001 22.1 0.1 0.0003 20.5 0.0 1.7 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 EAP30 PF04157.11 KOS22876.1 - 2.1e-51 174.2 0.0 2.7e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KOS22876.1 - 1.4e-26 92.1 0.0 2.7e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 KOS22876.1 - 0.00054 18.9 0.8 0.00054 18.9 0.5 2.6 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.15 KOS22876.1 - 0.0044 16.5 0.0 0.0092 15.4 0.0 1.5 1 0 0 1 1 1 1 GRAM domain zf-Sec23_Sec24 PF04810.10 KOS22876.1 - 0.025 14.1 0.5 0.025 14.1 0.4 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DZR PF12773.2 KOS22876.1 - 0.13 12.1 0.2 0.13 12.1 0.2 2.3 2 1 0 2 2 2 0 Double zinc ribbon HTH_Tnp_Tc5 PF03221.11 KOS22877.1 - 6.5e-18 64.3 2.7 3.3e-17 62.0 0.2 2.9 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain Hamartin PF04388.7 KOS22877.1 - 4.7 5.7 17.8 0.36 9.4 6.1 2.1 2 0 0 2 2 2 0 Hamartin protein CDK2AP PF09806.4 KOS22877.1 - 9.1 6.4 25.9 0.32 11.1 9.9 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF2611 PF11022.3 KOS22878.1 - 2.8e-24 84.9 0.1 3.1e-24 84.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) MTP18 PF10558.4 KOS22879.1 - 4e-67 224.7 0.1 5e-67 224.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) zf-AN1 PF01428.11 KOS22880.1 - 1.4e-23 82.4 19.6 6.9e-12 45.0 4.7 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 KOS22880.1 - 0.15 11.9 17.2 0.084 12.7 1.2 2.5 2 1 0 2 2 2 0 IBR domain Transp_Tc5_C PF04236.10 KOS22880.1 - 0.16 12.2 13.7 0.7 10.1 3.1 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Rad4 PF03835.10 KOS22881.1 - 2.6e-28 98.2 0.1 2.6e-28 98.2 0.1 2.4 3 0 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KOS22881.1 - 7.3e-27 92.9 0.3 1.4e-26 91.9 0.2 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KOS22881.1 - 6.3e-21 73.6 0.2 1.3e-20 72.6 0.2 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KOS22881.1 - 4.3e-15 55.7 0.0 4.3e-15 55.7 0.0 3.1 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KOS22881.1 - 0.0082 16.3 0.2 0.062 13.5 0.0 2.6 2 1 0 2 2 2 1 Transglutaminase-like superfamily DUF2036 PF09724.4 KOS22882.1 - 1.1e-07 31.3 0.0 1.3e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) SH3_1 PF00018.23 KOS22884.1 - 3.1e-28 96.9 0.0 2.6e-14 52.3 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KOS22884.1 - 6.6e-20 70.4 0.2 4.1e-10 39.0 0.1 3.2 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 KOS22884.1 - 1.4e-13 50.6 0.0 2.6e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 KOS22884.1 - 1.1e-11 43.9 0.0 2.7e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 KOS22884.1 - 1.1e-09 37.8 0.0 2.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Chorismate_bind PF00425.13 KOS22885.1 - 4.9e-87 291.4 0.0 6.6e-87 291.0 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 KOS22885.1 - 2.8e-26 92.1 0.5 8.1e-22 77.7 0.0 4.2 3 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region IMS PF00817.15 KOS22886.1 - 2.5e-35 121.4 0.0 3.7e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KOS22886.1 - 5.8e-07 29.4 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Imm45 PF15603.1 KOS22887.1 - 0.17 12.0 0.2 0.37 10.9 0.1 1.6 1 1 0 1 1 1 0 Immunity protein 45 bZIP_C PF12498.3 KOS22888.1 - 1.8 9.8 14.8 2.8 9.1 0.1 3.1 3 0 0 3 3 3 0 Basic leucine-zipper C terminal Macoilin PF09726.4 KOS22888.1 - 3.9 5.6 15.2 2.3 6.4 6.5 2.1 2 0 0 2 2 2 0 Transmembrane protein TPR_11 PF13414.1 KOS22889.1 - 5.2e-60 199.0 51.8 1.2e-14 53.6 1.2 6.9 2 2 7 9 9 9 9 TPR repeat TPR_1 PF00515.23 KOS22889.1 - 1.3e-55 182.8 38.1 1.8e-08 33.6 0.0 10.8 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 KOS22889.1 - 1.8e-49 161.6 26.6 6.5e-06 25.6 0.0 10.5 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 KOS22889.1 - 1.1e-36 121.7 25.6 4.7e-06 25.9 0.7 10.2 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 KOS22889.1 - 3.6e-35 119.8 17.2 6.9e-09 36.1 0.1 6.5 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 KOS22889.1 - 5.7e-34 113.4 22.6 0.00043 20.2 0.1 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 KOS22889.1 - 1.7e-29 101.5 24.9 1.2e-06 28.3 0.6 7.4 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 KOS22889.1 - 6e-29 97.8 16.0 0.00012 22.3 0.0 9.3 3 2 6 9 9 9 9 Tetratricopeptide repeat TPR_19 PF14559.1 KOS22889.1 - 2.1e-27 95.2 21.3 3e-07 30.6 0.2 7.0 3 3 2 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 KOS22889.1 - 3.9e-24 82.5 9.5 0.00088 18.9 0.0 9.8 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.1 KOS22889.1 - 2.2e-23 81.0 18.0 0.0078 16.6 0.0 9.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 KOS22889.1 - 3.6e-16 58.7 10.2 0.00031 20.5 0.1 6.4 1 1 6 7 7 7 7 Tetratricopeptide repeat Apc3 PF12895.2 KOS22889.1 - 1.6e-15 57.0 10.9 4.4e-09 36.3 1.7 4.6 4 2 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KOS22889.1 - 6.5e-13 48.3 8.9 0.00039 19.5 0.2 5.2 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_20 PF14561.1 KOS22889.1 - 2e-05 24.5 3.3 0.074 13.1 0.0 4.4 3 2 2 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.4 KOS22889.1 - 6.1e-05 22.5 4.1 0.0097 15.3 0.1 3.4 1 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_21 PF09976.4 KOS22889.1 - 0.00028 20.8 4.1 0.0056 16.6 2.2 4.7 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KOS22889.1 - 0.001 18.8 20.5 3.5 7.6 0.0 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KOS22889.1 - 0.0031 17.3 0.4 4.3 7.2 0.0 4.6 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 KOS22889.1 - 0.073 12.9 18.1 1.4 8.8 0.8 5.4 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain BTAD PF03704.12 KOS22889.1 - 0.083 13.1 7.8 5.2 7.3 0.1 3.3 3 0 0 3 3 3 0 Bacterial transcriptional activator domain SNAP PF14938.1 KOS22889.1 - 0.2 10.7 18.7 7 5.7 0.4 5.0 2 2 2 5 5 5 0 Soluble NSF attachment protein, SNAP Ribosomal_L3 PF00297.17 KOS22890.1 - 1.6e-118 394.8 8.5 1.9e-118 394.6 5.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 WD40 PF00400.27 KOS22891.1 - 2.3e-14 52.6 6.8 8.5e-07 28.6 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat LisH PF08513.6 KOS22891.1 - 1e-06 28.2 0.1 2.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 KOS22891.1 - 0.034 13.8 0.3 2.4 7.8 0.0 3.2 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Hid1 PF12722.2 KOS22891.1 - 2.6 5.6 3.7 3.4 5.2 2.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1751 PF08551.5 KOS22892.1 - 1.1e-25 89.8 5.0 2e-25 88.9 3.5 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KOS22892.1 - 1.7 8.6 11.4 3.4 7.6 7.9 1.4 1 0 0 1 1 1 0 Rhomboid family Reprolysin_5 PF13688.1 KOS22893.1 - 9.1e-57 192.1 0.2 9.1e-57 192.1 0.2 2.3 3 1 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KOS22893.1 - 1.2e-43 149.0 0.0 2.1e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KOS22893.1 - 1.5e-42 145.6 1.5 2.9e-42 144.6 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KOS22893.1 - 1.1e-18 67.2 32.2 1.1e-18 67.2 22.3 4.2 3 2 1 4 4 4 1 Disintegrin Reprolysin_3 PF13582.1 KOS22893.1 - 5.8e-17 62.3 0.0 1.8e-16 60.8 0.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.14 KOS22893.1 - 0.0056 16.4 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide tRNA_SAD PF07973.9 KOS22895.1 - 1e-06 28.4 0.2 2e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 KOS22895.1 - 0.0013 17.1 0.0 0.0019 16.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) Aldedh PF00171.17 KOS22896.1 - 4.6e-136 453.8 0.0 6.2e-136 453.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ABC2_membrane PF01061.19 KOS22897.1 - 3.4e-77 258.3 72.4 4.5e-40 137.0 19.8 3.0 3 1 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 KOS22897.1 - 9.8e-22 76.5 10.7 1.1e-17 63.6 0.0 3.0 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 KOS22897.1 - 2.8e-11 43.8 0.0 0.00021 21.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KOS22897.1 - 3.9e-10 39.3 14.2 3.9e-10 39.3 9.9 3.5 2 2 1 3 3 3 2 ABC-2 family transporter protein Methyltransf_23 PF13489.1 KOS22898.1 - 1.1e-17 64.2 0.0 1.6e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS22898.1 - 8.7e-11 42.1 0.0 1.7e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS22898.1 - 1.1e-08 35.6 0.0 1.3e-07 32.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS22898.1 - 2.2e-08 34.4 0.0 1.4e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS22898.1 - 3.5e-08 33.1 0.0 5.4e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KOS22898.1 - 1.2e-06 27.7 0.0 1.5e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KOS22898.1 - 0.00032 21.0 0.0 0.00097 19.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS22898.1 - 0.00068 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KOS22898.1 - 0.0014 17.6 0.0 0.0038 16.2 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 KOS22898.1 - 0.0023 17.9 0.0 0.0098 15.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KOS22898.1 - 0.0039 16.3 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KOS22898.1 - 0.0094 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.7 KOS22898.1 - 0.032 13.7 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 KOS22898.1 - 0.067 13.1 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase CMAS PF02353.15 KOS22898.1 - 0.14 11.1 0.0 0.38 9.7 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase ERCC4 PF02732.10 KOS22899.1 - 2.1e-17 63.2 0.0 2.8e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 ERCC4 domain His_Phos_1 PF00300.17 KOS22900.1 - 9.1e-21 74.5 0.2 3.3e-20 72.7 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DNA_binding_1 PF01035.15 KOS22901.1 - 8.4e-17 60.7 0.1 1.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Kinesin PF00225.18 KOS22902.1 - 2.1e-91 306.0 0.0 2.1e-91 306.0 0.0 3.8 4 0 0 4 4 4 1 Kinesin motor domain DUF500 PF04366.7 KOS22903.1 - 1.6e-45 153.5 0.0 2.5e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) FSH1 PF03959.8 KOS22904.1 - 2.6e-28 98.9 0.0 3.2e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KOS22904.1 - 0.02 14.3 0.4 1.1 8.6 0.1 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase 7tm_2 PF00002.19 KOS22905.1 - 3.3e-12 46.0 2.2 5e-12 45.4 1.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.3 KOS22905.1 - 0.0017 17.9 1.5 0.0017 17.9 1.0 1.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KOS22905.1 - 0.012 14.7 5.0 0.025 13.6 1.2 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF4131 PF13567.1 KOS22905.1 - 7.1 5.9 10.1 0.5 9.7 2.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) C2 PF00168.25 KOS22906.1 - 6.9e-11 41.8 0.0 1.2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain SAICAR_synt PF01259.13 KOS22907.1 - 7.2e-80 267.6 0.0 8.7e-80 267.4 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase GRP PF07172.6 KOS22908.1 - 0.0023 18.3 1.8 0.18 12.3 3.1 2.1 2 0 0 2 2 2 1 Glycine rich protein family TFIIF_alpha PF05793.7 KOS22908.1 - 4.9 5.4 4.7 6 5.1 3.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) p450 PF00067.17 KOS22909.1 - 1.2e-37 129.5 0.0 1.5e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.16 KOS22910.1 - 3.3e-31 108.5 0.0 4.3e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II AMP-binding PF00501.23 KOS22912.1 - 1.2e-100 336.8 0.5 4.2e-73 246.1 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KOS22912.1 - 3.6e-40 137.6 0.0 1.2e-24 86.7 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KOS22912.1 - 1.8e-23 82.5 1.7 1.1e-08 35.1 0.1 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KOS22912.1 - 9.7e-09 35.4 0.1 6.6e-08 32.7 0.0 2.5 3 0 0 3 3 3 1 HxxPF-repeated domain GST_C PF00043.20 KOS22914.1 - 7.8e-09 35.4 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KOS22914.1 - 1.3e-08 34.7 0.0 2.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KOS22914.1 - 4.3e-08 33.2 0.0 1e-07 32.0 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KOS22914.1 - 6.7e-07 29.7 0.0 1.2e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KOS22914.1 - 4.4e-05 23.5 0.0 9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KOS22914.1 - 0.0062 16.4 0.1 0.016 15.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Epimerase PF01370.16 KOS22915.1 - 7.2e-20 71.4 0.0 1.1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KOS22915.1 - 1.3e-11 43.8 0.0 1.4e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 KOS22915.1 - 9.9e-10 37.7 0.1 4.1e-08 32.4 0.0 2.7 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KOS22915.1 - 5.9e-09 35.2 0.0 1.2e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KOS22915.1 - 3.1e-06 26.1 0.0 5.9e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KOS22915.1 - 0.076 13.0 0.0 0.26 11.2 0.0 1.8 1 1 1 2 2 2 0 NADH(P)-binding Inositol_P PF00459.20 KOS22916.1 - 1.9e-35 122.5 1.0 2.8e-34 118.6 0.7 2.4 1 1 0 1 1 1 1 Inositol monophosphatase family DUF1656 PF07869.7 KOS22916.1 - 0.028 14.2 0.6 0.066 12.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Rep-A_N PF04057.7 KOS22917.1 - 0.027 14.2 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain TPP1 PF10341.4 KOS22917.1 - 0.16 11.9 0.0 0.37 10.8 0.0 1.6 1 1 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD F-box-like PF12937.2 KOS22918.1 - 1.7e-05 24.4 0.4 4.8e-05 22.9 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS22918.1 - 0.057 13.1 0.2 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 F-box domain MFS_1 PF07690.11 KOS22919.1 - 8.6e-09 34.5 44.3 8.7e-07 27.9 7.0 3.1 2 1 0 3 3 3 3 Major Facilitator Superfamily Nodulin-like PF06813.8 KOS22919.1 - 6.8e-07 28.7 13.9 0.0018 17.6 1.3 3.2 3 0 0 3 3 3 2 Nodulin-like ERG4_ERG24 PF01222.12 KOS22920.1 - 2.1e-86 290.1 0.3 2.6e-86 289.8 0.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KOS22920.1 - 1.8e-06 27.4 0.1 7.6e-06 25.3 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KOS22920.1 - 0.003 17.6 0.2 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 KOS22920.1 - 0.039 14.1 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family CAP_N PF01213.14 KOS22920.1 - 1.8 7.7 8.7 2.6 7.2 6.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mre11_DNA_bind PF04152.9 KOS22921.1 - 3.2e-54 183.4 0.1 8.6e-54 182.0 0.0 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KOS22921.1 - 2.1e-17 63.1 9.2 2.1e-16 59.9 6.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KOS22921.1 - 4.8e-06 26.4 0.1 1.7e-05 24.7 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CDC27 PF09507.5 KOS22921.1 - 0.063 12.5 14.4 0.1 11.8 10.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Daxx PF03344.10 KOS22921.1 - 1.7 7.0 13.3 2.5 6.4 9.2 1.2 1 0 0 1 1 1 0 Daxx Family CN_hydrolase PF00795.17 KOS22922.1 - 3.6e-22 78.6 0.0 6.7e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase WLM PF08325.5 KOS22923.1 - 8e-45 152.9 0.6 1.8e-44 151.8 0.0 1.7 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 KOS22923.1 - 0.0014 18.4 1.1 0.0014 18.4 0.8 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 KOS22923.1 - 0.014 15.0 0.2 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 SprT-like family Reprolysin_5 PF13688.1 KOS22923.1 - 0.018 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_MA_2 PF13485.1 KOS22923.1 - 0.027 14.5 0.4 0.072 13.1 0.1 1.8 2 0 0 2 2 2 0 Peptidase MA superfamily ER_lumen_recept PF00810.13 KOS22924.1 - 9.5e-54 181.8 4.0 1.5e-53 181.2 2.8 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KOS22924.1 - 0.047 13.2 6.3 1.1 8.8 0.0 3.6 2 1 1 3 3 3 0 PQ loop repeat Mito_carr PF00153.22 KOS22925.1 - 5.8e-52 173.3 3.3 9.1e-18 63.7 0.1 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3439 PF11921.3 KOS22925.1 - 0.13 11.9 14.0 0.24 11.1 9.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 KOS22925.1 - 0.15 11.8 15.8 0.28 10.9 10.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 KOS22925.1 - 1 7.0 5.6 1.3 6.6 3.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 KOS22925.1 - 1.6 6.6 16.0 2.2 6.1 11.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.6 KOS22925.1 - 7.5 4.2 6.5 10 3.8 4.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CheR_N PF03705.10 KOS22926.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain Nuf2 PF03800.9 KOS22927.1 - 4.1e-43 146.8 2.4 5.3e-43 146.4 0.0 2.1 2 0 0 2 2 2 1 Nuf2 family DUF948 PF06103.6 KOS22927.1 - 0.15 11.9 0.5 0.88 9.4 0.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 KOS22927.1 - 9.4 4.7 30.4 0.32 9.6 1.9 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Thioredoxin PF00085.15 KOS22928.1 - 4e-27 93.9 0.0 5e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KOS22928.1 - 1.7e-07 31.4 0.2 9.1e-07 29.0 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KOS22928.1 - 4.2e-06 26.8 0.1 3.2e-05 23.9 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KOS22928.1 - 3.7e-05 23.2 0.0 4.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KOS22928.1 - 0.0002 21.2 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KOS22928.1 - 0.0039 16.7 0.1 0.0087 15.6 0.0 1.5 1 1 0 1 1 1 1 Redoxin Glutaredoxin PF00462.19 KOS22928.1 - 0.0042 17.0 0.1 0.0091 15.9 0.1 1.6 1 1 0 1 1 1 1 Glutaredoxin HyaE PF07449.6 KOS22928.1 - 0.0082 16.0 0.0 0.015 15.1 0.0 1.4 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.1 KOS22928.1 - 0.044 13.3 0.0 1.6 8.3 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Methyltransf_PK PF05891.7 KOS22930.1 - 2.5e-62 210.0 0.0 3e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 KOS22930.1 - 0.01 16.4 0.0 0.043 14.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_52 PF03512.8 KOS22930.1 - 0.06 11.9 0.0 0.083 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 Methyltransf_25 PF13649.1 KOS22930.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_M50B PF13398.1 KOS22931.1 - 1.8e-55 187.4 19.5 2.2e-55 187.1 13.5 1.0 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 KOS22931.1 - 0.0088 15.0 0.8 0.0088 15.0 0.5 2.4 2 1 0 3 3 3 1 Peptidase family M50 YlaC PF10777.4 KOS22931.1 - 1.9 8.0 6.4 0.16 11.5 0.4 1.9 2 0 0 2 2 2 0 Inner membrane protein YlaC Epiglycanin_C PF14654.1 KOS22931.1 - 2 8.4 5.6 11 6.0 0.0 2.9 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region MLANA PF14991.1 KOS22931.1 - 2.3 8.2 7.6 0.66 9.9 0.6 2.3 1 1 1 2 2 2 0 Protein melan-A SpoVAB PF13782.1 KOS22931.1 - 5.6 6.9 11.7 0.63 10.0 2.3 2.8 3 1 0 3 3 3 0 Stage V sporulation protein AB Glyco_hydro_18 PF00704.23 KOS22932.1 - 3.1e-19 69.6 3.5 6.4e-19 68.5 0.2 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Fip1 PF05182.8 KOS22933.1 - 5.4e-20 70.3 0.7 1e-19 69.5 0.5 1.4 1 0 0 1 1 1 1 Fip1 motif DUF4455 PF14643.1 KOS22934.1 - 0.00037 19.2 0.4 0.066 11.8 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4455) Fzo_mitofusin PF04799.8 KOS22934.1 - 0.0056 16.0 1.5 0.026 13.9 0.0 2.3 2 1 0 2 2 2 1 fzo-like conserved region ISG65-75 PF11727.3 KOS22934.1 - 0.016 14.2 0.6 1.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein THDPS_N_2 PF14805.1 KOS22934.1 - 0.026 14.3 0.1 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Vps53_N PF04100.7 KOS22934.1 - 0.053 12.2 2.8 0.036 12.8 0.3 1.7 2 0 0 2 2 2 0 Vps53-like, N-terminal Spore_II_R PF09551.5 KOS22934.1 - 0.068 13.1 0.4 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) Flagellin_C PF00700.16 KOS22934.1 - 0.095 12.8 0.8 1.2 9.2 0.0 2.9 2 1 1 3 3 3 0 Bacterial flagellin C-terminal helical region Tup_N PF08581.5 KOS22934.1 - 0.1 12.7 1.8 5.9 7.1 0.6 2.4 2 0 0 2 2 2 0 Tup N-terminal Rootletin PF15035.1 KOS22934.1 - 0.15 12.0 2.3 4.7 7.1 0.1 2.6 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF2408 PF10303.4 KOS22934.1 - 0.3 11.1 1.7 1.1 9.3 0.1 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF2408) Syntaxin PF00804.20 KOS22934.1 - 0.39 10.8 5.1 2.7 8.1 0.5 2.8 2 1 0 3 3 3 0 Syntaxin SlyX PF04102.7 KOS22934.1 - 1 9.7 3.4 8.3 6.8 0.1 3.2 2 1 1 3 3 3 0 SlyX RNA_pol_3_Rpc31 PF11705.3 KOS22935.1 - 5.7e-27 95.1 39.1 8.2e-21 75.0 2.3 2.4 1 1 1 2 2 2 2 DNA-directed RNA polymerase III subunit Rpc31 Sec7 PF01369.15 KOS22937.1 - 5.7e-64 215.3 0.7 5.7e-64 215.3 0.5 3.0 3 1 1 4 4 4 1 Sec7 domain Sec7_N PF12783.2 KOS22937.1 - 2.6e-50 170.1 4.9 2.6e-50 170.1 3.4 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KOS22937.1 - 9.6e-33 111.5 4.2 2.7e-31 106.9 0.1 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) 2-oxoacid_dh PF00198.18 KOS22938.1 - 5.6e-78 261.3 0.1 7.3e-78 261.0 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KOS22938.1 - 7.9e-19 67.0 0.8 1.6e-18 66.0 0.6 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KOS22938.1 - 1.3e-14 53.5 0.7 3.3e-14 52.2 0.5 1.8 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.3 KOS22938.1 - 0.0032 17.7 0.3 0.0092 16.2 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3614) Biotin_lipoyl_2 PF13533.1 KOS22938.1 - 0.075 12.7 0.2 1.9 8.2 0.0 2.8 2 1 1 3 3 3 0 Biotin-lipoyl like Gar1 PF04410.9 KOS22940.1 - 1.3e-45 154.5 0.1 1.3e-45 154.5 0.1 2.9 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region Sld5 PF05916.6 KOS22941.1 - 2.3e-25 89.0 0.0 3.5e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Yos1 PF08571.5 KOS22942.1 - 1e-27 96.0 0.6 1.1e-27 95.8 0.4 1.0 1 0 0 1 1 1 1 Yos1-like PsbT PF01405.12 KOS22942.1 - 0.77 9.3 3.9 1.8 8.1 0.3 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre T protein Glyco_transf_22 PF03901.12 KOS22943.1 - 1.2e-84 284.7 19.3 1.4e-84 284.5 13.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Doppel PF11466.3 KOS22943.1 - 4.9 6.8 8.5 1 8.9 2.0 2.6 2 0 0 2 2 2 0 Prion-like protein Doppel Cpn60_TCP1 PF00118.19 KOS22944.1 - 4.6e-145 483.9 13.2 5.3e-145 483.7 9.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UCR_TM PF02921.9 KOS22945.1 - 5.8e-19 68.0 0.6 5.8e-19 68.0 0.4 1.8 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KOS22945.1 - 3.5e-17 61.7 0.0 5.4e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Acetyltransf_7 PF13508.1 KOS22946.1 - 1.2e-05 25.3 0.0 3.8e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS22946.1 - 0.00069 19.4 0.1 0.0022 17.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS22946.1 - 0.024 14.6 0.1 0.096 12.7 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family ProRS-C_1 PF09180.6 KOS22947.1 - 3.9e-21 74.7 0.1 9e-21 73.5 0.0 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 KOS22947.1 - 1.4e-19 70.3 0.0 2.3e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KOS22947.1 - 3e-17 62.3 0.0 1.2e-16 60.4 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain SPW PF03779.9 KOS22948.1 - 8.9 5.7 13.0 0.59 9.5 4.7 2.4 2 0 0 2 2 2 0 SPW repeat Methyltransf_23 PF13489.1 KOS22949.1 - 5.3e-11 42.5 0.0 8.4e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS22949.1 - 1.8e-10 41.4 0.1 4.3e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS22949.1 - 4.3e-10 39.3 0.0 5.9e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS22949.1 - 2.7e-08 34.1 0.1 5e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS22949.1 - 2e-05 24.5 0.2 3.5e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS22949.1 - 7.4e-05 23.1 0.0 0.00012 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KOS22949.1 - 0.0005 19.5 0.0 0.00075 18.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KOS22949.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 KOS22949.1 - 0.079 12.0 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NusA_N PF08529.6 KOS22949.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 NusA N-terminal domain DUF1793 PF08760.6 KOS22950.1 - 2.8e-57 193.2 1.3 3.5e-57 192.9 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 KOS22950.1 - 0.0026 16.9 0.5 0.0083 15.3 0.0 2.0 3 0 0 3 3 3 1 beta-Glucocerebrosidase 2 N terminal MFS_1 PF07690.11 KOS22951.1 - 8e-27 93.8 34.9 8e-27 93.8 24.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KOS22951.1 - 0.064 12.7 3.6 0.081 12.4 1.4 1.8 1 1 1 2 2 2 0 Ion channel regulatory protein UNC-93 DUF1616 PF07760.6 KOS22951.1 - 0.069 12.2 5.2 0.15 11.1 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) YCII PF03795.9 KOS22952.1 - 4.5e-08 33.1 0.0 5.2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain DUF2408 PF10303.4 KOS22953.1 - 2.9e-50 169.8 0.8 6.8e-29 100.6 0.0 5.0 3 1 1 5 5 5 3 Protein of unknown function (DUF2408) Phage_term_smal PF05944.7 KOS22953.1 - 0.045 13.4 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Phage small terminase subunit CARD PF00619.16 KOS22953.1 - 0.059 13.2 0.3 0.26 11.1 0.1 2.1 2 0 0 2 2 2 0 Caspase recruitment domain DUF1539 PF07560.6 KOS22953.1 - 0.09 12.6 0.7 0.23 11.3 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) UBA PF00627.26 KOS22954.1 - 0.00066 19.4 0.1 0.006 16.3 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain UBX PF00789.15 KOS22954.1 - 0.00068 19.6 0.0 0.0021 18.0 0.0 1.9 1 0 0 1 1 1 1 UBX domain RskA PF10099.4 KOS22954.1 - 0.013 15.2 2.4 0.013 15.2 1.6 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA zf-C2H2 PF00096.21 KOS22954.1 - 0.028 14.7 0.2 0.049 13.9 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Herpes_DNAp_acc PF04929.7 KOS22954.1 - 0.048 12.6 0.0 0.048 12.6 0.0 2.1 1 1 1 2 2 2 0 Herpes DNA replication accessory factor GHMP_kinases_N PF00288.21 KOS22954.1 - 0.075 13.1 0.2 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 GHMP kinases N terminal domain TFIIS_C PF01096.13 KOS22954.1 - 0.12 12.0 0.1 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) SOBP PF15279.1 KOS22954.1 - 0.19 12.0 5.2 0.23 11.8 3.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CpXC PF14353.1 KOS22954.1 - 9.2 6.2 10.2 10 6.1 6.2 1.8 1 1 0 1 1 1 0 CpXC protein CAP_GLY PF01302.20 KOS22955.1 - 4.7e-19 67.8 3.5 6.9e-19 67.3 2.4 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KOS22955.1 - 1.3e-17 63.8 0.0 1.8e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KOS22955.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Myb_DNA-binding PF00249.26 KOS22956.1 - 1.9e-11 43.8 2.2 6.4e-09 35.7 0.0 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KOS22956.1 - 4.8e-07 29.7 4.4 0.00037 20.5 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain TFIIA PF03153.8 KOS22956.1 - 3.6 7.3 9.7 4.9 6.9 6.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATP-synt_Eps PF04627.8 KOS22957.1 - 3.5e-23 80.8 3.1 6e-23 80.1 2.1 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF506 PF04720.7 KOS22958.1 - 0.68 9.5 7.0 1 8.9 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Tom37_C PF11801.3 KOS22958.1 - 2.8 7.7 6.5 0.54 10.1 2.0 1.7 2 0 0 2 2 2 0 Tom37 C-terminal domain Vfa1 PF08432.5 KOS22958.1 - 3.7 7.5 18.8 4.8 7.1 12.0 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Mito_carr PF00153.22 KOS22959.1 - 6.3e-52 173.2 5.1 5.7e-17 61.2 0.2 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 KOS22959.1 - 0.017 14.9 1.2 0.056 13.2 0.1 2.3 3 0 0 3 3 3 0 UcrQ family Sas10 PF09368.5 KOS22959.1 - 0.1 12.7 0.3 0.31 11.2 0.2 1.7 1 0 0 1 1 1 0 Sas10 C-terminal domain Mak10 PF04112.8 KOS22960.1 - 1.1e-37 128.8 0.0 1.9e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF3959 PF13105.1 KOS22961.1 - 0.96 8.7 3.6 1.1 8.5 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF3671 PF12420.3 KOS22961.1 - 1 9.3 3.4 1.9 8.5 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function zf-RING_2 PF13639.1 KOS22962.1 - 9.7e-14 50.9 4.7 9.7e-14 50.9 3.3 1.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KOS22962.1 - 4.2e-08 33.1 1.2 7.3e-08 32.4 0.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KOS22962.1 - 1.7e-07 30.7 3.9 3.1e-07 29.9 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS22962.1 - 2.4e-06 27.1 2.2 3.9e-06 26.4 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KOS22962.1 - 1.1e-05 25.4 5.3 1.7e-05 24.7 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS22962.1 - 3.3e-05 23.4 1.7 5.2e-05 22.8 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KOS22962.1 - 0.0012 18.6 0.4 0.0022 17.7 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KOS22962.1 - 0.014 14.9 2.7 0.024 14.1 1.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KOS22962.1 - 0.084 12.8 0.1 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain CPSase_sm_chain PF00988.17 KOS22962.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain zf-HC5HC2H PF13771.1 KOS22962.1 - 0.14 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.3 KOS22962.1 - 0.68 9.9 3.3 5.6 7.0 2.3 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 KOS22962.1 - 0.97 9.1 2.7 1.7 8.3 1.9 1.4 1 0 0 1 1 1 0 PHD-finger Glyco_hydro_cc PF11790.3 KOS22963.1 - 1.5e-53 181.7 0.3 1.9e-53 181.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Mur_ligase_M PF08245.7 KOS22965.1 - 3.1e-07 30.6 0.0 8.5e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Mur ligase middle domain Complex1_LYR PF05347.10 KOS22966.1 - 7.5e-08 32.0 0.8 1.7e-07 30.9 0.6 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KOS22966.1 - 1.7e-06 28.1 1.2 3.7e-06 27.0 0.8 1.6 1 0 0 1 1 1 1 Complex1_LYR-like DUF3329 PF11808.3 KOS22966.1 - 2.3 8.3 4.6 1.2 9.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) Thymidylat_synt PF00303.14 KOS22967.1 - 2.2e-105 351.5 0.0 5e-104 347.0 0.0 2.0 1 1 0 1 1 1 1 Thymidylate synthase MFS_1 PF07690.11 KOS22968.1 - 1.5e-32 112.7 25.4 1.5e-32 112.7 17.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1212 PF06738.7 KOS22968.1 - 0.41 10.0 7.2 0.06 12.7 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Acyl_transf_3 PF01757.17 KOS22968.1 - 0.78 8.5 33.5 0.16 10.7 7.2 2.3 2 0 0 2 2 2 0 Acyltransferase family Amidoligase_2 PF12224.3 KOS22969.1 - 2.2e-11 43.8 0.1 1.7e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme MFS_1 PF07690.11 KOS22970.1 - 2.9e-09 36.1 24.8 3.4e-09 35.8 17.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS22970.1 - 0.00056 18.5 6.4 0.00056 18.5 4.5 1.8 1 1 0 2 2 2 1 Sugar (and other) transporter DUF2613 PF11021.3 KOS22970.1 - 0.061 13.0 1.7 0.097 12.3 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2613) Acetyltransf_1 PF00583.19 KOS22971.1 - 2.3e-14 53.1 0.0 3.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KOS22971.1 - 2.6e-08 33.5 0.0 4.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KOS22971.1 - 5.5e-08 32.8 0.0 8.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KOS22971.1 - 1e-06 28.9 0.0 1.9e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS22971.1 - 2.8e-06 27.4 0.0 4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KOS22971.1 - 0.0012 18.7 0.0 0.0074 16.2 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KOS22971.1 - 0.0053 16.6 0.0 0.019 14.8 0.0 1.9 2 1 1 3 3 3 1 GCN5-related N-acetyl-transferase AA_permease_2 PF13520.1 KOS22973.1 - 1.2e-89 300.8 36.9 1.5e-89 300.4 25.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KOS22973.1 - 5.5e-20 71.1 29.4 9.6e-20 70.3 20.4 1.3 1 1 0 1 1 1 1 Amino acid permease Glyco_hydro_92 PF07971.7 KOS22976.1 - 3.7e-161 537.1 0.0 4.8e-161 536.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_16 PF00722.16 KOS22977.1 - 2.4e-42 144.3 0.8 3.6e-42 143.7 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sec63 PF02889.11 KOS22978.1 - 2.4e-23 82.8 0.0 3.5e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain HHH_5 PF14520.1 KOS22978.1 - 3.8e-05 23.7 0.3 8.1e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain DUF4332 PF14229.1 KOS22978.1 - 0.00011 22.2 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) DUF605 PF04652.11 KOS22979.1 - 7.9 5.7 10.3 11 5.3 7.1 1.1 1 0 0 1 1 1 0 Vta1 like Band_7 PF01145.20 KOS22980.1 - 1.1e-28 100.3 2.1 1.3e-28 100.1 0.4 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KOS22980.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family UQ_con PF00179.21 KOS22981.1 - 5.5e-17 61.5 0.0 6e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KOS22981.1 - 0.0049 16.7 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain Flavoprotein PF02441.14 KOS22983.1 - 1.1e-12 47.7 0.0 2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein UQ_con PF00179.21 KOS22984.1 - 1e-34 118.9 0.1 1.3e-34 118.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF572 PF04502.8 KOS22985.1 - 4e-41 141.3 0.0 5.1e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) DLH PF01738.13 KOS22986.1 - 2.1e-11 43.5 0.0 2.6e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KOS22986.1 - 0.0041 16.8 0.1 0.0058 16.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_20 PF00728.17 KOS22987.1 - 8.3e-95 317.9 0.4 1e-94 317.6 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KOS22987.1 - 9e-22 78.0 0.0 1.7e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KOS22987.1 - 5.7e-06 26.8 0.0 1.4e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Pro_isomerase PF00160.16 KOS22988.1 - 1.3e-32 113.1 0.0 2e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KOS22988.1 - 3.1e-15 55.5 0.0 5.5e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS22988.1 - 3.2e-10 39.8 0.0 5.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS22988.1 - 8.6e-09 35.1 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_27 PF13514.1 KOS22989.1 - 0.0044 14.7 1.0 0.0054 14.5 0.7 1.0 1 0 0 1 1 1 1 AAA domain FliT PF05400.8 KOS22989.1 - 0.016 15.6 8.2 0.16 12.3 1.9 2.8 2 1 0 2 2 2 0 Flagellar protein FliT Activator_LAG-3 PF11498.3 KOS22989.1 - 0.045 12.5 0.1 0.052 12.3 0.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 ARGLU PF15346.1 KOS22989.1 - 0.067 12.9 0.7 0.067 12.9 0.5 1.8 2 1 0 2 2 2 0 Arginine and glutamate-rich 1 HARP PF07443.8 KOS22989.1 - 0.2 11.0 0.8 1.9 7.9 0.1 2.2 2 0 0 2 2 2 0 HepA-related protein (HARP) Asp_Glu_race PF01177.17 KOS22990.1 - 7.2e-20 71.8 0.0 1.3e-19 71.0 0.0 1.4 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Zn_clus PF00172.13 KOS22991.1 - 7.7e-09 35.3 7.0 1.2e-08 34.7 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gly-zipper_OmpA PF13436.1 KOS22991.1 - 0.0074 15.9 21.4 0.0074 15.9 14.8 2.6 2 0 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain PAT1 PF09770.4 KOS22991.1 - 1.1 7.4 15.4 1.4 7.0 10.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Actin PF00022.14 KOS22992.1 - 4.5e-116 387.5 0.0 5.3e-116 387.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KOS22992.1 - 0.00098 17.8 0.0 0.0068 15.0 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein Arf PF00025.16 KOS22993.1 - 3.3e-74 247.9 0.2 3.8e-74 247.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KOS22993.1 - 3.4e-13 49.2 0.0 3.8e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KOS22993.1 - 2.6e-11 42.8 2.1 6.6e-08 31.6 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KOS22993.1 - 1.3e-10 40.7 0.0 1.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KOS22993.1 - 1.8e-09 37.0 0.0 2.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KOS22993.1 - 7.6e-08 32.8 0.0 1.1e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KOS22993.1 - 0.00076 19.4 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KOS22993.1 - 0.045 12.8 0.1 0.075 12.1 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase T3SS_LEE_assoc PF13327.1 KOS22993.1 - 0.047 13.2 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system subunit AAA_33 PF13671.1 KOS22993.1 - 0.16 11.8 0.2 1.3 8.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain HAD_2 PF13419.1 KOS22994.1 - 1.9e-16 60.8 0.0 2.7e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS22994.1 - 5.2e-07 30.2 0.0 4.3e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KOS22994.1 - 9.3e-06 25.2 0.0 2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like TENA_THI-4 PF03070.11 KOS22995.1 - 4.1e-07 29.9 0.0 0.032 13.9 0.0 2.3 2 0 0 2 2 2 2 TENA/THI-4/PQQC family Fungal_trans_2 PF11951.3 KOS22996.1 - 4.8e-06 25.4 0.0 6.5e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_11 PF13414.1 KOS22997.1 - 8.7e-11 41.3 4.6 8.7e-11 41.3 3.2 1.9 2 1 1 3 3 3 1 TPR repeat TPR_12 PF13424.1 KOS22997.1 - 6.9e-06 25.9 3.2 1.6e-05 24.7 2.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 KOS22997.1 - 2.8e-05 23.6 6.8 0.067 13.1 1.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 KOS22997.1 - 0.00037 20.3 0.7 0.21 11.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KOS22997.1 - 0.00043 19.7 6.6 0.069 12.7 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS22997.1 - 0.0057 16.9 1.4 0.0057 16.9 0.9 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KOS22997.1 - 0.019 15.6 6.4 0.019 15.6 4.4 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KOS22997.1 - 0.027 15.0 0.8 0.027 15.0 0.6 3.8 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KOS22997.1 - 0.052 13.3 3.7 3 7.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KOS22997.1 - 0.22 11.6 3.2 0.61 10.2 2.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KOS22997.1 - 3 8.5 6.7 56 4.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Pantoate_ligase PF02569.10 KOS22998.1 - 9.4e-84 280.4 0.0 2e-83 279.4 0.0 1.5 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Robl_LC7 PF03259.12 KOS22998.1 - 0.099 12.2 0.1 1 8.9 0.0 2.5 2 0 0 2 2 2 0 Roadblock/LC7 domain WD40 PF00400.27 KOS22999.1 - 2.7e-08 33.4 0.0 9.7e-06 25.2 0.0 2.9 2 1 0 2 2 2 2 WD domain, G-beta repeat UPF0086 PF01868.11 KOS23000.1 - 4e-24 84.0 0.0 6.7e-24 83.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Acyltransferase PF01553.16 KOS23001.1 - 1.2e-17 63.5 0.0 2.5e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase DUF2076 PF09849.4 KOS23002.1 - 0.014 15.4 16.4 0.019 15.0 11.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Zip PF02535.17 KOS23002.1 - 0.85 8.5 7.8 1.1 8.1 5.2 1.2 1 1 0 1 1 1 0 ZIP Zinc transporter Sugar_tr PF00083.19 KOS23003.1 - 4.4e-39 134.3 21.7 8.1e-39 133.4 15.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS23003.1 - 4.9e-36 124.1 43.9 2e-32 112.2 18.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KOS23003.1 - 6.4e-05 21.6 23.4 0.00057 18.4 3.4 2.2 1 1 0 2 2 2 2 Vacuole effluxer Atg22 like Ank PF00023.25 KOS23004.1 - 1.3e-16 59.4 1.7 7.2e-08 31.8 0.4 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KOS23004.1 - 1.5e-13 50.9 0.4 4.3e-05 23.7 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KOS23004.1 - 1.5e-12 47.6 0.5 0.00033 21.0 0.3 3.5 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KOS23004.1 - 1.2e-10 41.2 0.9 9.2e-06 25.7 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS23004.1 - 4.3e-09 35.7 0.2 0.045 13.9 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat AAA_13 PF13166.1 KOS23004.1 - 0.51 8.7 2.7 0.94 7.8 1.9 1.3 1 0 0 1 1 1 0 AAA domain Actin PF00022.14 KOS23005.1 - 6.2e-124 413.4 0.0 7.6e-124 413.1 0.0 1.0 1 0 0 1 1 1 1 Actin DnaJ PF00226.26 KOS23006.1 - 3.2e-23 81.2 0.5 5.5e-23 80.4 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KOS23006.1 - 4.5e-14 52.2 18.1 8.3e-14 51.3 12.5 1.5 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 KOS23006.1 - 2.2e-13 49.9 0.0 1.4e-12 47.3 0.0 2.3 3 0 0 3 3 3 1 DnaJ C terminal domain HypA PF01155.14 KOS23006.1 - 0.00071 19.2 8.2 0.074 12.7 0.3 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family zf-C3HC4_3 PF13920.1 KOS23006.1 - 0.42 10.3 7.5 0.084 12.5 1.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 KOS23006.1 - 0.95 9.3 11.6 4.5 7.1 2.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.1 KOS23006.1 - 1.3 8.7 9.2 0.89 9.3 1.5 2.4 2 0 0 2 2 2 0 zinc-RING finger domain OB_NTP_bind PF07717.11 KOS23007.1 - 2e-27 95.3 0.0 6.3e-27 93.6 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KOS23007.1 - 7.9e-24 83.6 0.1 7.9e-24 83.6 0.1 3.5 4 1 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KOS23007.1 - 1e-12 47.7 0.0 2.5e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KOS23007.1 - 7.4e-06 26.1 0.1 2.9e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 KOS23007.1 - 0.00013 21.5 0.1 0.00033 20.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KOS23007.1 - 0.00041 19.3 0.0 0.001 18.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 KOS23007.1 - 0.028 13.8 0.5 0.11 11.9 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 KOS23007.1 - 0.087 12.7 2.4 0.32 10.8 0.1 2.9 2 1 0 2 2 2 0 AAA domain GYD PF08734.6 KOS23007.1 - 0.11 12.2 0.8 19 5.0 0.0 3.2 3 0 0 3 3 3 0 GYD domain ABC_tran PF00005.22 KOS23007.1 - 0.32 11.3 0.0 0.32 11.3 0.0 2.4 2 1 0 2 2 2 0 ABC transporter 2OG-FeII_Oxy_3 PF13640.1 KOS23008.1 - 5.5e-12 46.0 0.2 9.6e-12 45.3 0.2 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KOS23008.1 - 2e-05 24.1 0.1 4.5e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.8 KOS23008.1 - 0.0029 17.6 0.0 0.035 14.1 0.0 2.2 1 1 1 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Cu-oxidase_3 PF07732.10 KOS23009.1 - 2.8e-39 133.4 0.4 7.5e-39 132.1 0.2 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KOS23009.1 - 3.7e-37 126.8 6.3 1.6e-25 89.2 0.9 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KOS23009.1 - 5.7e-17 62.0 0.0 6.2e-16 58.7 0.0 2.6 3 1 0 3 3 3 1 Multicopper oxidase DUF3602 PF12223.3 KOS23010.1 - 1.2e-09 38.4 14.2 0.0015 18.8 0.3 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DUF1183 PF06682.7 KOS23010.1 - 5 6.6 6.6 7.9 5.9 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Glyco_hydro_76 PF03663.9 KOS23011.1 - 2.3e-147 491.2 8.1 3e-147 490.8 5.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KOS23011.1 - 0.27 10.2 9.6 1.5 7.8 0.2 3.1 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 COPIIcoated_ERV PF07970.7 KOS23012.1 - 1.3e-37 129.6 0.1 1.8e-37 129.1 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KOS23012.1 - 5e-20 71.2 0.0 8.4e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Gly-zipper_OmpA PF13436.1 KOS23013.1 - 0.059 13.0 0.0 0.059 13.0 0.0 2.4 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Peptidase_M24 PF00557.19 KOS23014.1 - 2.7e-49 167.5 0.1 4.6e-49 166.8 0.1 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KOS23014.1 - 9.5e-35 118.9 0.0 1.7e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.5 KOS23015.1 - 6.3e-38 129.3 0.0 1.4e-37 128.2 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KOS23015.1 - 3e-22 78.0 0.4 5.1e-22 77.2 0.2 1.4 1 0 0 1 1 1 1 DBF zinc finger DUF1777 PF08648.7 KOS23015.1 - 0.0011 18.6 15.7 0.0011 18.6 10.9 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1777) PTCB-BRCT PF12738.2 KOS23015.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain APG12 PF04110.8 KOS23016.1 - 1.5e-25 89.1 0.0 2.2e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 KOS23016.1 - 0.0015 18.4 0.0 0.0019 18.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 KOS23017.1 - 3.2e-103 344.4 0.1 3.7e-103 344.2 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KOS23017.1 - 2.7e-10 39.8 0.1 5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase zf-DHHC PF01529.15 KOS23018.1 - 8.1e-29 100.2 5.3 8.1e-29 100.2 3.7 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase stn_TNFRSF12A PF12191.3 KOS23018.1 - 0.57 10.2 3.2 1.3 9.0 1.9 1.8 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SRA1 PF07304.6 KOS23021.1 - 0.11 12.2 1.0 0.17 11.5 0.2 1.6 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Aha1_N PF09229.6 KOS23022.1 - 5.7e-37 126.5 1.5 8.5e-37 126.0 1.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KOS23022.1 - 1e-16 61.1 0.3 1.9e-16 60.2 0.2 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein HMG_CoA_synt_C PF08540.5 KOS23023.1 - 1.1e-99 333.5 0.7 1.4e-99 333.1 0.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KOS23023.1 - 1.8e-82 275.0 0.1 2.8e-82 274.4 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal FAD_binding_4 PF01565.18 KOS23024.1 - 2.2e-15 56.3 0.0 3.4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FXR1P_C PF12235.3 KOS23025.1 - 1.5 8.8 6.2 2.2 8.3 4.3 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Acetyltransf_7 PF13508.1 KOS23026.1 - 2e-06 27.8 0.0 4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS23026.1 - 3.9e-06 26.8 0.0 6.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KOS23026.1 - 0.0026 17.4 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KOS23026.1 - 0.014 15.4 0.0 0.021 14.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TEX13 PF15186.1 KOS23027.1 - 0.61 9.6 11.4 0.94 9.0 7.3 1.6 1 1 0 1 1 1 0 Testis-expressed sequence 13 protein family Spore_coat_CotO PF14153.1 KOS23027.1 - 8.6 5.7 12.7 13 5.1 8.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO BCS1_N PF08740.6 KOS23030.1 - 2.2e-51 174.1 0.1 2.2e-51 174.1 0.0 2.7 3 0 0 3 3 3 1 BCS1 N terminal AAA PF00004.24 KOS23030.1 - 4.9e-15 55.9 0.0 2e-13 50.6 0.0 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KOS23030.1 - 0.00023 20.6 0.2 0.0038 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KOS23030.1 - 0.00065 19.4 0.2 0.03 14.0 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 KOS23030.1 - 0.0031 17.2 0.3 0.029 14.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KOS23030.1 - 0.017 15.0 0.2 0.089 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KOS23030.1 - 0.028 15.2 0.0 0.028 15.2 0.0 3.3 3 1 0 3 3 1 0 AAA domain RuvB_N PF05496.7 KOS23030.1 - 0.058 12.4 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Drf_DAD PF06345.6 KOS23030.1 - 0.092 12.5 1.1 0.19 11.5 0.8 1.6 1 0 0 1 1 1 0 DRF Autoregulatory Domain Ycf1 PF05758.7 KOS23030.1 - 0.47 8.1 25.0 0.76 7.4 17.3 1.4 1 0 0 1 1 1 0 Ycf1 FAM60A PF15396.1 KOS23030.1 - 8.6 6.0 20.3 19 4.9 14.0 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Glyco_hydro_47 PF01532.15 KOS23031.1 - 1.5e-129 432.6 0.0 2.2e-128 428.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 WD40 PF00400.27 KOS23032.1 - 2.2e-49 163.6 20.3 1.5e-11 43.6 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KOS23032.1 - 1.8e-09 37.5 7.6 0.015 15.0 0.1 4.4 3 1 2 5 5 5 3 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 KOS23032.1 - 1 7.0 2.9 12 3.5 0.4 2.4 2 1 0 2 2 2 0 IKI3 family GCS PF03074.11 KOS23034.1 - 5e-155 516.1 0.0 1.2e-154 514.8 0.0 1.6 1 1 0 1 1 1 1 Glutamate-cysteine ligase DUF2373 PF10180.4 KOS23035.1 - 1.4e-19 69.3 0.0 3.1e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) PhyH PF05721.8 KOS23036.1 - 1.1e-59 202.0 0.0 1.3e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Claudin_2 PF13903.1 KOS23037.1 - 5.1e-05 23.0 3.9 9.1e-05 22.2 2.6 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 KOS23037.1 - 0.0013 18.7 5.4 0.0057 16.6 3.2 2.1 1 1 1 2 2 2 1 Lipoma HMGIC fusion partner-like protein DUF4173 PF13777.1 KOS23037.1 - 0.0019 17.4 1.3 0.0019 17.4 0.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4173) DUF3816 PF12822.2 KOS23037.1 - 0.0096 15.8 1.3 0.014 15.2 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3816) MARVEL PF01284.18 KOS23037.1 - 3.8 7.3 15.0 42 3.9 10.6 2.4 1 1 0 1 1 1 0 Membrane-associating domain CN_hydrolase PF00795.17 KOS23038.1 - 2e-32 112.0 0.0 3.7e-32 111.1 0.0 1.4 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Spermine_synth PF01564.12 KOS23039.1 - 4.8e-97 323.7 0.0 6.2e-97 323.3 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 KOS23039.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS23039.1 - 0.0027 18.2 0.0 0.0051 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 KOS23039.1 - 0.015 14.3 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 KOS23039.1 - 0.028 14.8 0.2 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 KOS23039.1 - 0.066 12.9 0.0 0.21 11.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KOS23039.1 - 0.097 11.8 0.2 1.1 8.3 0.0 2.2 1 1 1 2 2 2 0 O-methyltransferase G-alpha PF00503.15 KOS23040.1 - 1.6e-87 293.7 0.0 1.9e-87 293.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KOS23040.1 - 9.6e-09 34.7 0.1 2.2e-08 33.5 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Fn3-like PF14310.1 KOS23042.1 - 2.4e-23 81.8 0.2 4e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.17 KOS23042.1 - 2.9e-18 66.2 0.1 1.4e-16 60.6 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain DUF1265 PF06887.9 KOS23042.1 - 0.18 11.4 0.1 0.36 10.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) Pkinase PF00069.20 KOS23043.1 - 3.6e-19 68.9 0.0 7e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS23043.1 - 5.5e-10 38.7 0.0 2.3e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1515 PF07439.6 KOS23043.1 - 0.065 13.0 0.2 14 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Neisseria_TspB PF05616.8 KOS23043.1 - 3.8 5.7 5.8 5.8 5.1 4.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein SIR2 PF02146.12 KOS23044.1 - 5.5e-57 192.3 0.0 9.1e-57 191.6 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KOS23044.1 - 0.0033 17.0 0.0 0.007 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 KOS23044.1 - 0.042 13.6 0.1 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Neisseria_TspB PF05616.8 KOS23044.1 - 1.8 6.8 4.4 2.6 6.3 3.1 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein zf-primase PF09329.6 KOS23045.1 - 3.2e-19 68.2 0.9 5.8e-19 67.4 0.6 1.5 1 0 0 1 1 1 1 Primase zinc finger Tyrosinase PF00264.15 KOS23046.1 - 8.2e-48 163.4 3.4 8.2e-48 163.4 2.4 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase RNase_H2-Ydr279 PF09468.5 KOS23048.1 - 5.8e-61 206.3 3.8 8.7e-61 205.7 2.7 1.3 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF3340 PF11818.3 KOS23048.1 - 0.099 12.5 7.8 0.26 11.2 5.4 1.6 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Spt5_N PF11942.3 KOS23048.1 - 1.4 9.6 13.1 0.86 10.2 5.4 2.7 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Pyr_redox_2 PF07992.9 KOS23049.1 - 9.3e-14 51.7 0.0 1.4e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KOS23049.1 - 0.00026 19.9 0.0 0.00048 19.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KOS23049.1 - 0.0008 18.4 0.4 0.0031 16.4 0.1 2.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 KOS23049.1 - 0.002 17.0 1.1 0.16 10.7 0.4 2.2 1 1 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.9 KOS23049.1 - 0.0029 16.1 0.1 0.0065 14.9 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 KOS23049.1 - 0.0034 17.1 0.6 0.4 10.4 0.3 2.2 1 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KOS23049.1 - 0.0043 17.1 0.2 1.6 8.7 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KOS23049.1 - 0.0057 15.7 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.1 KOS23049.1 - 0.0084 15.0 0.1 1.4 7.7 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KOS23049.1 - 0.012 15.5 0.2 0.032 14.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KOS23049.1 - 0.014 14.4 0.0 0.33 10.0 0.1 2.5 3 0 0 3 3 3 0 Thi4 family Glyco_hydro_18 PF00704.23 KOS23050.1 - 7.4e-17 61.8 1.9 4.7e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 KOS23050.1 - 0.081 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Caerin_1 PF07440.7 KOS23050.1 - 0.12 12.2 1.9 0.23 11.3 1.3 1.5 1 0 0 1 1 1 0 Caerin 1 protein ABC_membrane PF00664.18 KOS23051.1 - 1.9e-86 289.8 36.8 1.2e-45 156.0 8.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KOS23051.1 - 1.6e-47 161.2 0.0 3.7e-36 124.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KOS23051.1 - 1.4e-16 60.3 0.9 1.7e-06 27.4 0.0 3.3 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KOS23051.1 - 2e-13 51.0 0.0 0.00018 21.6 0.0 3.3 3 0 0 3 3 3 3 AAA domain ABC_ATPase PF09818.4 KOS23051.1 - 3.7e-06 25.7 2.7 0.0087 14.6 0.2 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 KOS23051.1 - 0.00043 19.7 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KOS23051.1 - 0.0005 20.2 0.0 0.039 14.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KOS23051.1 - 0.00058 20.6 0.0 0.0013 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS23051.1 - 0.00083 19.3 0.0 0.0056 16.6 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KOS23051.1 - 0.001 18.2 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KOS23051.1 - 0.006 16.4 8.7 0.082 12.8 0.2 4.0 4 2 0 4 4 3 2 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 KOS23051.1 - 0.02 14.7 0.2 0.044 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_10 PF12846.2 KOS23051.1 - 0.024 14.0 0.0 0.071 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.7 KOS23051.1 - 0.1 12.2 0.4 0.44 10.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 KOS23051.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KOS23051.1 - 0.16 12.2 0.0 0.44 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KOS23051.1 - 0.22 11.4 1.2 0.59 10.1 0.2 2.4 2 1 0 2 2 1 0 50S ribosome-binding GTPase AAA_15 PF13175.1 KOS23051.1 - 0.28 10.1 0.0 3.4 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DegT_DnrJ_EryC1 PF01041.12 KOS23053.1 - 1.3e-69 235.0 0.0 1.7e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GFO_IDH_MocA PF01408.17 KOS23053.1 - 5.3e-18 65.6 0.0 1.4e-17 64.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KOS23053.1 - 1.4e-06 28.0 0.0 3.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.14 KOS23053.1 - 2.3e-06 27.9 0.0 5.5e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Beta_elim_lyase PF01212.16 KOS23053.1 - 0.00013 21.2 0.0 0.00022 20.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Semialdhyde_dh PF01118.19 KOS23053.1 - 0.0055 16.9 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Aminotran_5 PF00266.14 KOS23053.1 - 0.0058 15.4 0.0 0.0092 14.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KOS23053.1 - 0.0081 14.4 0.0 0.014 13.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PEX11 PF05648.9 KOS23054.1 - 4.8e-70 235.2 0.2 5.4e-70 235.1 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) BBE PF08031.7 KOS23055.1 - 1.5e-11 43.9 0.1 4.3e-11 42.5 0.1 1.9 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 KOS23055.1 - 3.7e-08 32.9 1.2 9.1e-08 31.6 0.2 2.0 1 1 1 2 2 2 1 FAD binding domain Methyltransf_25 PF13649.1 KOS23056.1 - 1e-11 45.1 0.0 1.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS23056.1 - 3.9e-11 43.5 0.0 6.4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS23056.1 - 1.3e-09 38.0 0.2 2.2e-09 37.3 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS23056.1 - 1.2e-08 35.3 0.0 1.8e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS23056.1 - 1.1e-07 31.7 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS23056.1 - 1.4e-07 31.9 0.0 2.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS23056.1 - 1.4e-07 31.2 0.0 2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS23056.1 - 4.6e-06 26.1 0.0 7.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 KOS23056.1 - 5e-05 22.3 0.0 0.0017 17.3 0.0 2.1 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.13 KOS23056.1 - 0.00031 19.9 0.0 0.00043 19.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KOS23056.1 - 0.0006 18.9 0.0 0.00097 18.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 KOS23056.1 - 0.0062 15.9 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_PK PF05891.7 KOS23056.1 - 0.0095 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_3 PF01596.12 KOS23056.1 - 0.11 11.5 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase ABC_tran PF00005.22 KOS23057.1 - 3.6e-70 234.6 0.0 1e-34 119.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KOS23057.1 - 9.8e-66 221.9 34.3 7.5e-38 130.5 8.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KOS23057.1 - 4e-17 62.1 2.5 0.00011 21.5 0.6 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KOS23057.1 - 9.4e-12 45.4 0.1 0.038 13.9 0.0 4.2 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 KOS23057.1 - 2.7e-09 36.4 0.5 0.002 17.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KOS23057.1 - 1.8e-08 35.0 0.0 0.0043 17.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KOS23057.1 - 2.1e-08 33.2 0.3 0.0026 16.4 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KOS23057.1 - 3.6e-08 33.6 2.3 0.0014 18.6 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KOS23057.1 - 2.3e-07 30.9 0.9 0.028 14.5 0.0 4.0 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 KOS23057.1 - 3e-07 29.7 0.6 0.026 13.7 0.0 3.3 4 0 0 4 4 4 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KOS23057.1 - 3.4e-07 31.1 0.0 0.029 15.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KOS23057.1 - 3.9e-06 26.6 0.4 0.014 15.2 0.1 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KOS23057.1 - 9.4e-05 22.7 0.0 1.1 9.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain DEAD PF00270.24 KOS23057.1 - 0.0001 21.8 0.2 0.46 9.9 0.0 3.1 2 1 0 2 2 2 2 DEAD/DEAH box helicase IstB_IS21 PF01695.12 KOS23057.1 - 0.00012 21.5 0.1 0.22 10.9 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KOS23057.1 - 0.00016 20.9 0.0 0.19 10.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI MobB PF03205.9 KOS23057.1 - 0.00017 21.3 0.1 0.2 11.3 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KOS23057.1 - 0.00031 20.4 0.0 0.15 11.6 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KOS23057.1 - 0.00042 20.1 0.0 0.58 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KOS23057.1 - 0.00046 19.7 4.8 0.69 9.2 0.1 3.7 4 0 0 4 4 4 2 AAA-like domain AAA_5 PF07728.9 KOS23057.1 - 0.0007 19.3 0.1 6 6.5 0.0 3.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KOS23057.1 - 0.00083 18.5 0.0 0.59 9.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.12 KOS23057.1 - 0.00094 19.0 1.0 1.2 8.8 0.1 2.7 3 0 0 3 3 2 2 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 KOS23057.1 - 0.0014 18.5 0.1 1.4 8.8 0.0 3.4 4 0 0 4 4 2 1 50S ribosome-binding GTPase AAA_25 PF13481.1 KOS23057.1 - 0.0019 17.6 1.7 2 7.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 KOS23057.1 - 0.0039 17.3 3.8 13 6.0 0.1 4.4 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KOS23057.1 - 0.0083 15.6 0.0 2.1 7.7 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain Gtr1_RagA PF04670.7 KOS23057.1 - 0.014 14.5 0.1 1.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 KOS23057.1 - 0.018 14.5 0.2 5.4 6.4 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family APS_kinase PF01583.15 KOS23057.1 - 0.032 13.8 0.3 2.3 7.8 0.0 2.9 3 0 0 3 3 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 KOS23057.1 - 0.051 13.7 0.0 24 5.1 0.0 3.3 3 0 0 3 3 2 0 RNA helicase NB-ARC PF00931.17 KOS23057.1 - 0.089 11.6 0.0 7.4 5.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain ResIII PF04851.10 KOS23057.1 - 0.11 12.2 0.0 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit G-alpha PF00503.15 KOS23057.1 - 0.5 8.9 0.1 1.6 7.2 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit Ank_2 PF12796.2 KOS23058.1 - 6.1e-18 64.9 0.8 9.9e-18 64.2 0.6 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KOS23058.1 - 3.1e-15 56.2 0.3 6.6e-11 42.4 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KOS23058.1 - 9.2e-15 53.6 6.8 2.4e-05 23.9 0.3 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KOS23058.1 - 4.3e-13 48.1 0.8 0.0062 16.6 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KOS23058.1 - 1e-12 47.8 3.3 6.7e-05 23.0 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Bacteroid_pep PF14406.1 KOS23058.1 - 0.36 10.9 0.2 0.36 10.9 0.1 2.3 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Bacteroidetes bZIP_1 PF00170.16 KOS23058.1 - 0.46 10.4 9.2 0.8 9.7 6.4 1.3 1 0 0 1 1 1 0 bZIP transcription factor YCII PF03795.9 KOS23059.1 - 0.052 13.7 0.0 0.071 13.3 0.0 1.1 1 0 0 1 1 1 0 YCII-related domain PXA PF02194.10 KOS23060.1 - 2.8e-50 170.4 0.7 6.3e-50 169.3 0.0 1.9 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 KOS23060.1 - 6e-29 100.4 1.9 9.5e-29 99.7 0.0 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 KOS23060.1 - 1.9e-20 72.7 0.6 6.1e-20 71.1 0.4 1.9 1 0 0 1 1 1 1 PX domain RGS PF00615.14 KOS23060.1 - 8.8e-12 45.1 0.0 3.1e-11 43.3 0.0 2.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF2964 PF11177.3 KOS23060.1 - 0.11 12.4 0.9 0.32 10.9 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) RRM_1 PF00076.17 KOS23061.1 - 3e-10 39.5 0.0 3.7e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS23061.1 - 7.3e-08 32.2 0.0 8.8e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS23061.1 - 0.016 15.0 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSD PF00313.17 KOS23061.1 - 0.15 11.8 0.2 0.35 10.6 0.1 1.6 1 1 1 2 2 2 0 'Cold-shock' DNA-binding domain RE_EcoO109I PF14511.1 KOS23062.1 - 0.096 12.0 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I Chitin_synth_1 PF01644.12 KOS23063.1 - 1.9e-80 268.3 0.3 3.8e-80 267.4 0.2 1.5 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.6 KOS23063.1 - 6.6e-31 105.8 0.0 1.4e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KOS23063.1 - 1.6e-23 82.9 2.8 4.1e-18 65.0 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KOS23063.1 - 6.7e-07 29.2 16.0 1.3e-06 28.2 8.2 3.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KOS23063.1 - 1.5e-06 28.1 0.0 5.1e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Pro-kuma_activ PF09286.6 KOS23064.1 - 6.7e-24 84.5 0.0 2e-23 83.0 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KOS23064.1 - 8.7e-08 31.6 0.0 1.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Translin PF01997.11 KOS23065.1 - 3.3e-40 137.8 0.0 3.8e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Translin family Gpi1 PF05024.10 KOS23065.1 - 0.061 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) GMP_synt_C PF00958.17 KOS23065.1 - 0.13 11.9 0.0 0.44 10.2 0.0 1.8 2 1 0 2 2 2 0 GMP synthase C terminal domain PRP38_assoc PF12871.2 KOS23066.1 - 3.6e-05 24.2 34.1 3.6e-05 24.2 23.6 5.3 5 0 0 5 5 5 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term zf-CCCH PF00642.19 KOS23066.1 - 0.00022 20.8 4.1 0.00039 20.0 2.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1777 PF08648.7 KOS23066.1 - 0.0015 18.3 33.7 0.0015 18.3 23.3 4.9 6 0 0 6 6 6 1 Protein of unknown function (DUF1777) Sec1 PF00995.18 KOS23067.1 - 3.6e-150 501.2 0.0 4.2e-150 501.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Ino80_Iec3 PF14612.1 KOS23068.1 - 7e-57 193.1 0.3 6.9e-56 189.8 0.2 2.3 1 1 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling TMF_DNA_bd PF12329.3 KOS23068.1 - 0.012 15.4 0.3 0.023 14.5 0.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Nucleo_P87 PF07267.6 KOS23068.1 - 0.27 9.8 8.3 0.43 9.2 5.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1777 PF08648.7 KOS23068.1 - 3.1 7.4 54.2 0.12 12.0 33.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Hex_IIIa PF02455.11 KOS23068.1 - 8.1 5.0 10.3 13 4.3 7.2 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Iso_dh PF00180.15 KOS23069.1 - 1e-69 235.1 0.0 1.2e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2543 PF10820.3 KOS23069.1 - 0.12 12.3 0.6 0.23 11.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) adh_short PF00106.20 KOS23070.1 - 1.2e-30 106.6 3.2 1.9e-30 106.0 2.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS23070.1 - 9.5e-19 68.1 0.0 1.1e-18 67.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS23070.1 - 1.2e-13 51.1 1.6 1.8e-13 50.5 1.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KOS23070.1 - 8.9e-05 22.0 0.6 0.00019 20.9 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KOS23070.1 - 0.0018 17.2 0.1 0.0089 14.9 0.1 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.5 KOS23070.1 - 0.052 12.6 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Methyltransf_19 PF04672.7 KOS23070.1 - 0.08 12.1 0.1 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 S-adenosyl methyltransferase NAD_binding_10 PF13460.1 KOS23070.1 - 0.13 12.2 3.9 1.3 8.9 2.7 2.5 1 1 0 1 1 1 0 NADH(P)-binding Filament PF00038.16 KOS23071.1 - 0.00013 21.5 18.4 0.00013 21.5 12.8 4.2 2 1 1 4 4 4 2 Intermediate filament protein Taxilin PF09728.4 KOS23071.1 - 0.0045 16.1 3.8 0.0045 16.1 2.6 3.9 4 1 0 4 4 4 1 Myosin-like coiled-coil protein FlaC_arch PF05377.6 KOS23071.1 - 0.012 15.5 18.2 1.1 9.1 0.1 6.1 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 KOS23071.1 - 0.012 15.3 2.3 0.012 15.3 1.6 7.5 7 1 1 8 8 8 0 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KOS23071.1 - 0.04 13.1 7.9 0.69 9.0 0.6 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 KOS23071.1 - 2.8 7.7 69.0 0.039 13.8 18.6 4.8 5 0 0 5 5 5 0 Tropomyosin like TMCO5 PF14992.1 KOS23071.1 - 4.8 6.2 45.8 0.11 11.6 3.3 3.8 3 1 0 3 3 3 0 TMCO5 family M_domain PF12938.2 KOS23071.1 - 7 6.3 7.8 0.81 9.4 0.5 2.6 2 1 0 2 2 2 0 M domain of GW182 S4 PF01479.20 KOS23072.1 - 3.3e-12 45.6 0.0 9.1e-12 44.2 0.0 1.7 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.14 KOS23072.1 - 2.2e-10 40.7 2.7 3e-10 40.3 1.5 1.5 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Herpes_LAMP2 PF06126.6 KOS23072.1 - 0.043 12.2 0.1 0.049 12.0 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Ribosomal_S18 PF01084.15 KOS23073.1 - 7.5e-10 38.5 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 TFIIF_alpha PF05793.7 KOS23073.1 - 1.4 7.2 5.9 1.8 6.8 4.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SNF2_N PF00176.18 KOS23074.1 - 5.9e-27 94.2 0.2 9.3e-27 93.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 KOS23074.1 - 5.9e-22 77.3 1.5 1.3e-21 76.2 1.1 1.6 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 KOS23074.1 - 3.2e-14 52.5 0.0 1.9e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS23074.1 - 0.00044 20.1 0.5 0.012 15.4 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Methyltransf_23 PF13489.1 KOS23075.1 - 1.1e-12 48.0 0.0 2.1e-12 47.0 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS23075.1 - 6.2e-07 29.9 0.0 1.1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS23075.1 - 8.2e-07 29.4 0.0 3.4e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS23075.1 - 4.4e-06 27.0 0.0 8.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS23075.1 - 3.6e-05 23.3 0.0 5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS23075.1 - 0.0017 18.3 0.0 0.0072 16.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KOS23075.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family EamA PF00892.15 KOS23076.1 - 3.4e-10 40.0 24.6 1.2e-05 25.3 3.3 2.5 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KOS23076.1 - 2.6e-05 24.4 1.4 2.6e-05 24.4 1.0 2.8 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 KOS23076.1 - 1.1 8.9 16.0 0.27 10.8 3.0 2.9 3 1 0 3 3 3 0 Triose-phosphate Transporter family AMP-binding PF00501.23 KOS23077.1 - 1.4e-84 283.9 0.0 2e-84 283.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Acyl_transf_1 PF00698.16 KOS23077.1 - 5.3e-62 209.9 0.0 8e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KOS23077.1 - 7.3e-61 205.8 0.0 1.4e-60 204.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KOS23077.1 - 2.4e-57 193.5 2.6 3e-57 193.1 0.0 2.6 3 0 0 3 3 2 1 KR domain PS-DH PF14765.1 KOS23077.1 - 1.2e-50 172.4 0.0 1.8e-50 171.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KOS23077.1 - 1.2e-47 161.8 4.3 2.6e-47 160.8 0.0 3.4 3 0 0 3 3 3 1 short chain dehydrogenase Condensation PF00668.15 KOS23077.1 - 1.6e-39 135.6 0.0 2.4e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.17 KOS23077.1 - 1e-38 131.8 0.1 6.2e-38 129.3 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KOS23077.1 - 1.7e-37 128.7 0.0 4.8e-37 127.2 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein ADH_zinc_N PF00107.21 KOS23077.1 - 1.4e-19 69.9 0.0 4.2e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KOS23077.1 - 3.8e-19 68.7 0.0 1.8e-08 34.5 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KOS23077.1 - 9.5e-12 45.0 0.0 3e-11 43.4 0.0 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain ADH_zinc_N_2 PF13602.1 KOS23077.1 - 9.1e-10 39.5 0.0 1.7e-08 35.4 0.0 3.3 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KOS23077.1 - 1.1e-06 28.3 0.0 2.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.14 KOS23077.1 - 0.0054 15.4 0.0 0.12 11.0 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family PPR_3 PF13812.1 KOS23078.1 - 1.5e-12 46.7 3.1 0.023 14.9 0.0 7.8 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR PF01535.15 KOS23078.1 - 4.5e-06 26.2 1.8 0.78 9.8 0.0 5.7 6 0 0 6 6 6 2 PPR repeat PPR_2 PF13041.1 KOS23078.1 - 1.7e-05 24.6 0.0 7 6.7 0.0 5.5 5 1 1 6 6 6 2 PPR repeat family Aldo_ket_red PF00248.16 KOS23079.1 - 2e-50 171.1 0.0 2.3e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_3 PF01494.14 KOS23081.1 - 4e-17 62.2 0.1 4.6e-14 52.2 0.1 2.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KOS23081.1 - 0.0011 18.9 0.8 0.0026 17.7 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KOS23081.1 - 0.0091 15.1 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KOS23081.1 - 0.014 15.7 0.1 0.042 14.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KOS23081.1 - 0.049 12.4 0.6 0.093 11.5 0.4 1.5 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.16 KOS23081.1 - 0.053 13.0 0.0 0.49 9.9 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 KOS23081.1 - 0.066 11.8 0.2 0.17 10.4 0.1 1.6 1 1 0 2 2 2 0 Tryptophan halogenase Med15 PF09606.5 KOS23082.1 - 0.1 10.8 70.9 0.13 10.4 49.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DWNN PF08783.6 KOS23082.1 - 0.68 9.9 4.1 0.84 9.6 1.6 1.9 2 0 0 2 2 2 0 DWNN domain Exonuc_VII_L PF02601.10 KOS23082.1 - 1.7 7.7 16.7 2.4 7.2 11.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pkinase PF00069.20 KOS23083.1 - 4.6e-69 232.4 0.0 7.5e-69 231.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS23083.1 - 1.4e-49 168.5 0.0 2.2e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS23083.1 - 0.00044 19.2 0.0 0.001 18.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Ric8 PF10165.4 KOS23083.1 - 0.023 13.5 1.0 0.32 9.7 0.7 2.2 1 1 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Kdo PF06293.9 KOS23083.1 - 0.043 12.8 0.0 0.083 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DHquinase_I PF01487.10 KOS23083.1 - 0.19 11.3 0.3 0.47 10.0 0.0 1.7 2 0 0 2 2 2 0 Type I 3-dehydroquinase ICE2 PF08426.5 KOS23084.1 - 4.1e-138 460.4 10.9 4.7e-138 460.2 7.5 1.0 1 0 0 1 1 1 1 ICE2 Aa_trans PF01490.13 KOS23085.1 - 1.6e-21 76.2 30.5 2.1e-21 75.9 21.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PRT_C PF08372.5 KOS23085.1 - 1.4 8.3 3.7 4.4 6.7 0.1 2.8 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal MFS_1 PF07690.11 KOS23087.1 - 1.8e-19 69.6 37.2 5.5e-19 68.0 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PMP1_2 PF08114.6 KOS23087.1 - 0.48 9.9 4.1 0.35 10.4 0.1 2.7 2 0 0 2 2 2 0 ATPase proteolipid family DUF202 PF02656.10 KOS23087.1 - 8.4 6.6 12.8 7.7 6.8 2.2 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF202) adh_short PF00106.20 KOS23088.1 - 0.00049 20.0 0.1 0.0017 18.3 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS23088.1 - 0.016 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 KR domain KH_1 PF00013.24 KOS23089.1 - 2.5e-86 283.2 28.5 7.1e-13 47.9 0.1 13.5 15 0 0 15 15 15 9 KH domain KH_3 PF13014.1 KOS23089.1 - 8.9e-62 203.9 24.6 1.1e-09 37.6 0.1 12.1 12 0 0 12 12 12 9 KH domain SLS PF14611.1 KOS23089.1 - 2.5e-12 46.6 3.6 0.023 14.1 0.0 6.6 5 2 3 8 8 8 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 KOS23089.1 - 1.4e-10 40.5 22.9 0.074 12.6 0.1 8.0 7 1 1 8 8 8 4 KH domain KH_5 PF13184.1 KOS23089.1 - 4.4e-05 23.2 3.0 10 5.9 0.0 5.6 5 0 0 5 5 5 2 NusA-like KH domain KH_4 PF13083.1 KOS23089.1 - 0.022 14.3 12.0 5.6 6.6 0.0 5.9 5 1 1 6 6 6 0 KH domain Dermcidin PF15291.1 KOS23089.1 - 4 7.6 11.3 2.5 8.3 2.7 3.4 3 1 0 3 3 3 0 Dermcidin, antibiotic peptide Pkinase PF00069.20 KOS23090.1 - 1.9e-72 243.5 0.0 3.2e-72 242.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS23090.1 - 1.7e-46 158.4 0.0 3.1e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KOS23090.1 - 4.2e-16 59.0 0.0 4.2e-16 59.0 0.0 3.1 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 KOS23090.1 - 3.9e-08 32.6 0.0 6.3e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.7 KOS23090.1 - 0.2 10.8 0.0 0.41 9.8 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain adh_short PF00106.20 KOS23091.1 - 4.6e-31 107.9 1.8 6.8e-31 107.4 1.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS23091.1 - 8.6e-27 94.4 0.2 1.1e-26 94.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS23091.1 - 6.5e-13 48.7 0.3 9.6e-13 48.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KOS23091.1 - 1.1e-06 28.3 0.2 3.6e-06 26.5 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.17 KOS23091.1 - 7.3e-06 25.6 0.2 1.8e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 PA domain Polysacc_synt_2 PF02719.10 KOS23091.1 - 0.0064 15.4 0.0 0.015 14.2 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein ARID PF01388.16 KOS23093.1 - 4.3e-16 58.5 0.0 1.1e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Tim54 PF11711.3 KOS23093.1 - 0.075 11.6 1.1 0.14 10.7 0.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Macoilin PF09726.4 KOS23093.1 - 4.5 5.4 13.7 6.5 4.9 9.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Dioxygenase_C PF00775.16 KOS23094.1 - 5.6e-45 152.8 0.0 7.2e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KOS23094.1 - 4.3e-12 45.8 0.0 6.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Lactonase PF10282.4 KOS23095.1 - 4.4e-14 52.3 0.0 7.1e-14 51.6 0.0 1.3 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Ribosom_S12_S23 PF00164.20 KOS23096.1 - 7.8e-41 138.3 0.7 9.2e-41 138.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Inhibitor_I9 PF05922.11 KOS23097.1 - 0.001 19.5 0.0 0.0013 19.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 HOOK PF05622.7 KOS23098.1 - 9.8e-12 43.5 44.3 9.8e-12 43.5 30.7 2.2 1 1 1 2 2 2 1 HOOK protein Reo_sigmaC PF04582.7 KOS23098.1 - 0.015 14.4 27.7 0.028 13.6 0.5 4.0 2 2 1 4 4 4 0 Reovirus sigma C capsid protein ThiS PF02597.15 KOS23098.1 - 0.68 10.3 10.0 10 6.6 0.0 4.8 4 1 0 4 4 4 0 ThiS family MscS_porin PF12795.2 KOS23098.1 - 0.74 9.0 104.8 0.044 13.1 16.5 5.8 2 2 3 5 5 5 0 Mechanosensitive ion channel porin domain WEMBL PF05701.6 KOS23098.1 - 2.5 6.4 87.0 0.57 8.5 23.5 3.3 1 1 2 3 3 3 0 Weak chloroplast movement under blue light HrpA_pilin PF09589.5 KOS23098.1 - 3.9 7.9 21.7 0.79 10.1 7.3 4.0 1 1 1 2 2 2 0 HrpA pilus formation protein ADK PF00406.17 KOS23099.1 - 1.8e-59 199.9 0.0 2.8e-59 199.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KOS23099.1 - 7.4e-15 54.3 0.0 2.6e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KOS23099.1 - 9.1e-07 29.7 0.0 1.7e-06 28.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KOS23099.1 - 8.3e-06 25.7 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KOS23099.1 - 0.0025 18.1 0.0 0.0053 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS23099.1 - 0.021 13.9 0.0 0.032 13.3 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin MitMem_reg PF13012.1 KOS23100.1 - 3.3e-38 130.2 0.3 7.4e-38 129.1 0.1 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KOS23100.1 - 2.8e-29 101.1 0.0 6.2e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SWIM PF04434.12 KOS23101.1 - 0.00064 19.1 1.5 0.55 9.7 0.0 2.4 2 0 0 2 2 2 2 SWIM zinc finger SipA PF09052.5 KOS23101.1 - 0.085 11.2 0.5 0.11 10.8 0.4 1.1 1 0 0 1 1 1 0 Salmonella invasion protein A Atg8 PF02991.11 KOS23102.1 - 2.5e-51 171.9 0.2 3e-51 171.7 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KOS23102.1 - 2.5e-06 27.5 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Sugar_tr PF00083.19 KOS23103.1 - 8.7e-73 245.4 21.9 1.1e-72 245.0 15.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS23103.1 - 3.3e-16 58.9 24.3 4.4e-14 51.9 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KOS23103.1 - 4.6e-05 21.9 34.7 0.0034 15.8 3.5 3.7 3 1 1 4 4 4 3 MFS/sugar transport protein Complex1_LYR_2 PF13233.1 KOS23104.1 - 1.6e-17 63.9 0.0 1.8e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Inositol_P PF00459.20 KOS23105.1 - 9.7e-52 175.9 3.5 2.9e-51 174.3 2.4 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family DUF2630 PF10944.3 KOS23105.1 - 0.12 12.4 0.5 0.24 11.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Sec1 PF00995.18 KOS23106.1 - 2.4e-136 455.6 0.0 2.8e-136 455.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Apo-CIII PF05778.7 KOS23106.1 - 0.00054 19.2 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 Apolipoprotein CIII (Apo-CIII) Exo5 PF09810.4 KOS23107.1 - 2.8e-97 325.8 0.0 3.4e-97 325.5 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease ThiF PF00899.16 KOS23108.1 - 3.8e-51 172.4 0.0 2.7e-32 111.4 0.0 2.9 3 0 0 3 3 3 2 ThiF family UBACT PF02134.16 KOS23108.1 - 2.2e-37 126.4 4.2 9.6e-27 92.3 0.2 2.8 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KOS23108.1 - 4.1e-37 127.1 0.0 8.9e-37 126.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KOS23108.1 - 4.1e-24 83.6 5.1 8.8e-20 69.8 1.3 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site F-box-like PF12937.2 KOS23109.1 - 3.1e-07 29.9 4.8 0.00077 19.1 0.2 2.8 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 KOS23109.1 - 0.00087 18.8 4.3 0.069 12.8 0.2 2.7 2 0 0 2 2 2 2 F-box domain His_Phos_1 PF00300.17 KOS23110.1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.3 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Peptidase_M20 PF01546.23 KOS23111.1 - 1.7e-08 34.1 0.5 2.8e-08 33.5 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KOS23111.1 - 4.2e-08 32.8 0.0 1.3e-06 28.1 0.0 2.9 2 1 0 2 2 2 1 Peptidase dimerisation domain His_Phos_1 PF00300.17 KOS23112.1 - 0.00095 19.2 0.1 0.0025 17.9 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TFIIF_alpha PF05793.7 KOS23112.1 - 3.4 5.9 10.0 5.2 5.3 7.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Amino_oxidase PF01593.19 KOS23113.1 - 2.4e-44 152.1 0.5 2.5e-41 142.2 0.3 2.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KOS23113.1 - 4.5e-16 58.6 0.1 1.1e-15 57.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KOS23113.1 - 6.7e-06 26.3 0.0 0.00018 21.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS23113.1 - 6.7e-05 23.2 0.1 0.00029 21.1 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KOS23113.1 - 0.00016 20.6 1.2 0.00037 19.5 0.5 1.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KOS23113.1 - 0.00032 19.6 0.0 0.00069 18.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KOS23113.1 - 0.00041 20.1 0.0 0.056 13.2 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KOS23113.1 - 0.00051 18.6 0.0 0.0011 17.5 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KOS23113.1 - 0.00081 19.3 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KOS23113.1 - 0.001 18.2 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 KOS23113.1 - 0.0039 16.8 0.1 0.0079 15.8 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KOS23113.1 - 0.0048 16.0 0.2 0.0068 15.5 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.14 KOS23113.1 - 0.04 12.1 0.0 0.053 11.7 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like XdhC_C PF13478.1 KOS23113.1 - 0.1 12.9 0.0 6 7.1 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain GIDA PF01134.17 KOS23113.1 - 0.14 10.9 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ATG2_CAD PF13329.1 KOS23114.1 - 2.2e-46 157.2 0.0 4.3e-46 156.3 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 KOS23114.1 - 1.5e-28 98.7 0.6 2.1e-27 95.1 0.0 2.8 2 0 0 2 2 2 1 ATG C terminal domain Chorein_N PF12624.2 KOS23114.1 - 0.026 14.0 0.2 0.34 10.4 0.0 2.4 2 0 0 2 2 2 0 N-terminal region of Chorein, a TM vesicle-mediated sorter Glyco_transf_8 PF01501.15 KOS23115.1 - 9.7e-25 87.3 0.0 1.1e-23 83.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Cerato-platanin PF07249.7 KOS23118.1 - 7.1e-48 161.5 2.0 8.4e-48 161.3 1.4 1.0 1 0 0 1 1 1 1 Cerato-platanin Cpn60_TCP1 PF00118.19 KOS23119.1 - 2.9e-146 487.9 3.5 3.6e-146 487.6 2.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GTP_EFTU PF00009.22 KOS23120.1 - 1.1e-49 168.4 0.0 2e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HET PF06985.6 KOS23120.1 - 2.9e-31 108.5 1.9 4.4e-31 107.9 0.0 2.3 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HBS1_N PF08938.5 KOS23120.1 - 4.3e-18 65.2 0.2 4.3e-18 65.2 0.1 2.7 2 0 0 2 2 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 KOS23120.1 - 3e-08 33.6 0.1 1.7e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 KOS23120.1 - 5.5e-07 29.5 0.1 1.5e-06 28.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 KOS23120.1 - 0.0031 18.0 0.1 0.024 15.1 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein Septin PF00735.13 KOS23120.1 - 0.019 14.0 0.0 0.034 13.1 0.0 1.4 1 0 0 1 1 1 0 Septin Peptidase_S24 PF00717.18 KOS23120.1 - 0.038 13.6 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Peptidase S24-like RXT2_N PF08595.6 KOS23120.1 - 0.043 13.6 2.7 0.14 11.9 1.9 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal GTP_EFTU_D3 PF03143.12 KOS23120.1 - 0.044 13.9 0.0 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain Dynamin_N PF00350.18 KOS23120.1 - 0.048 13.4 4.5 6.6 6.5 0.0 3.7 3 1 1 4 4 4 0 Dynamin family SRPRB PF09439.5 KOS23120.1 - 0.084 12.0 0.3 3.6 6.7 0.0 2.9 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Ras PF00071.17 KOS23120.1 - 0.18 11.1 0.1 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Ras family CDC45 PF02724.9 KOS23120.1 - 0.78 7.7 5.2 0.31 9.0 1.6 1.7 2 0 0 2 2 2 0 CDC45-like protein Rhabdo_ncap PF00945.13 KOS23120.1 - 1.1 7.7 2.5 2.1 6.8 1.7 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Arf PF00025.16 KOS23120.1 - 1.1 8.4 3.5 19 4.4 0.1 2.6 3 0 0 3 3 3 0 ADP-ribosylation factor family DUF506 PF04720.7 KOS23120.1 - 3.8 7.0 6.5 11 5.5 4.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Glyoxalase PF00903.20 KOS23121.1 - 8.9e-38 129.1 0.2 3.3e-18 65.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KOS23121.1 - 3.7e-34 117.5 0.9 9.1e-20 71.2 0.2 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KOS23121.1 - 1.1e-18 67.2 0.1 2.1e-08 34.1 0.0 3.1 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KOS23121.1 - 7.2e-09 35.7 0.1 0.00038 20.3 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase-like domain GATase_2 PF00310.16 KOS23122.1 - 2.4e-17 62.6 0.0 1.1e-12 47.3 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II Pribosyltran PF00156.22 KOS23122.1 - 3e-13 49.5 0.2 6.2e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_6 PF13522.1 KOS23122.1 - 3.6e-13 49.6 0.0 8.1e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KOS23122.1 - 1.6e-10 40.8 0.0 2.9e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Fe_hyd_lg_C PF02906.9 KOS23122.1 - 0.054 12.7 0.0 0.44 9.7 0.0 2.2 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain PITH PF06201.8 KOS23122.1 - 0.058 13.1 0.1 4.6 6.9 0.0 2.2 2 0 0 2 2 2 0 PITH domain VirB3 PF05101.8 KOS23123.1 - 0.077 12.9 1.3 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein ATP-grasp_2 PF08442.5 KOS23125.1 - 7.7e-79 263.7 0.9 1.2e-78 263.1 0.6 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KOS23125.1 - 3.1e-26 91.8 0.5 7.3e-26 90.6 0.4 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KOS23125.1 - 1e-06 28.1 0.2 1.9e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Peripla_BP_2 PF01497.13 KOS23125.1 - 0.00029 20.0 0.8 0.001 18.2 0.1 1.9 2 0 0 2 2 2 1 Periplasmic binding protein GARS_A PF01071.14 KOS23125.1 - 0.0012 18.4 1.2 0.014 14.9 0.2 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 KOS23125.1 - 0.0087 15.5 0.2 0.46 9.9 0.0 2.5 1 1 1 2 2 2 1 RimK-like ATP-grasp domain OKR_DC_1_N PF03709.10 KOS23125.1 - 0.08 13.0 0.1 0.68 9.9 0.0 2.6 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain PRMT5 PF05185.11 KOS23126.1 - 5.4e-06 25.6 0.0 6.3e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 KOS23126.1 - 0.00014 22.2 0.0 0.00043 20.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS23126.1 - 0.00015 22.3 0.0 0.00072 20.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS23126.1 - 0.042 13.8 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Complex1_30kDa PF00329.14 KOS23127.1 - 3.3e-34 117.2 0.0 5e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF2570 PF10828.3 KOS23128.1 - 0.0089 15.6 4.0 0.0089 15.6 2.8 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF2570) NAD_binding_5 PF07994.7 KOS23128.1 - 0.9 8.9 5.1 0.66 9.4 2.5 1.5 1 1 0 1 1 1 0 Myo-inositol-1-phosphate synthase Reo_sigmaC PF04582.7 KOS23128.1 - 2 7.5 17.0 6.5 5.8 8.9 2.5 1 1 2 3 3 3 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KOS23128.1 - 2.2 6.6 30.3 0.93 7.8 5.3 2.1 1 1 1 2 2 2 0 AAA domain Peptidase_C6 PF00851.13 KOS23128.1 - 2.7 6.5 10.9 0.091 11.3 1.0 2.1 1 1 1 2 2 2 0 Helper component proteinase DUF4172 PF13776.1 KOS23128.1 - 2.8 8.1 7.4 0.56 10.3 0.9 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4172) E1_dh PF00676.15 KOS23129.1 - 7.7e-86 287.4 0.0 9.3e-86 287.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KOS23129.1 - 5.9e-05 22.6 0.1 0.00089 18.8 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 KOS23129.1 - 0.014 14.3 0.0 0.061 12.2 0.0 2.0 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase SGS PF05002.10 KOS23129.1 - 2.1 8.1 5.3 15 5.4 1.8 3.0 2 1 1 3 3 3 0 SGS domain Ubie_methyltran PF01209.13 KOS23130.1 - 2.7e-78 262.2 0.0 3.3e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KOS23130.1 - 2.9e-13 50.1 0.0 1.4e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS23130.1 - 1.6e-12 47.2 0.0 2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS23130.1 - 4.2e-11 43.1 0.0 6.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS23130.1 - 3.7e-10 39.7 0.0 5.3e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS23130.1 - 1.1e-08 35.3 0.0 1.7e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS23130.1 - 3.6e-08 33.9 0.0 6.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS23130.1 - 8e-06 25.8 0.0 2.1e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KOS23130.1 - 0.018 14.7 0.0 0.1 12.2 0.0 2.1 3 0 0 3 3 3 0 Hypothetical methyltransferase MTS PF05175.9 KOS23130.1 - 0.087 12.1 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Suf PF05843.9 KOS23131.1 - 0.36 10.5 2.5 0.42 10.3 1.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 KOS23131.1 - 0.57 9.5 15.9 0.67 9.2 11.0 1.1 1 0 0 1 1 1 0 Vta1 like HEAT PF02985.17 KOS23132.1 - 0.00039 20.2 0.3 0.045 13.8 0.0 3.5 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 KOS23132.1 - 0.014 15.2 0.7 0.81 9.6 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Complex1_51K PF01512.12 KOS23133.1 - 3e-48 163.3 0.0 5e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KOS23133.1 - 3.4e-18 64.5 0.9 3.4e-18 64.5 0.7 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KOS23133.1 - 2.4e-09 36.9 0.0 5.4e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 SLBB domain Sec3_C PF09763.4 KOS23134.1 - 1.5e-197 657.9 2.8 6.4e-111 371.6 0.3 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec3 Sec3_C_2 PF15278.1 KOS23134.1 - 0.00073 19.6 3.3 0.019 15.0 0.0 3.6 4 0 0 4 4 4 1 Sec3 exocyst complex subunit RsbRD_N PF14361.1 KOS23134.1 - 0.14 12.6 6.2 2.9 8.3 0.0 3.8 4 0 0 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain Sclerostin PF05463.6 KOS23135.1 - 0.018 14.5 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Sclerostin (SOST) Acetyltransf_1 PF00583.19 KOS23136.1 - 2.5e-14 53.0 0.0 4.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KOS23136.1 - 9.8e-07 28.4 0.1 1.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KOS23136.1 - 0.0015 18.6 0.0 0.0034 17.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KOS23136.1 - 0.016 15.3 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS23136.1 - 0.024 14.5 0.1 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NIF PF03031.13 KOS23137.1 - 8.8e-40 135.9 0.0 1.4e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PBP1_TM PF14812.1 KOS23137.1 - 4.2 7.7 12.3 0.066 13.5 2.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ORC6 PF05460.8 KOS23137.1 - 6.6 5.7 8.5 9.5 5.2 5.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) IF-2B PF01008.12 KOS23138.1 - 3.3e-45 154.2 0.0 9.5e-45 152.7 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 KOS23138.1 - 0.12 12.0 0.1 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Ribosomal_L7Ae PF01248.21 KOS23139.1 - 2.2e-21 75.1 0.5 1e-20 73.0 0.4 2.1 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FAM91_C PF14648.1 KOS23139.1 - 0.093 11.5 3.0 0.14 10.9 2.1 1.2 1 0 0 1 1 1 0 FAM91 C-terminus Ycf1 PF05758.7 KOS23139.1 - 0.5 8.0 4.3 0.46 8.1 2.9 1.1 1 0 0 1 1 1 0 Ycf1 DUF1761 PF08570.5 KOS23140.1 - 5.8e-22 78.0 0.4 6.5e-22 77.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Band_7 PF01145.20 KOS23141.1 - 5.9e-24 84.9 5.4 9.3e-24 84.3 3.6 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 KOS23141.1 - 0.027 13.8 1.3 0.037 13.4 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) YdfA_immunity PF12127.3 KOS23141.1 - 0.057 12.3 5.6 0.074 11.9 3.9 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial GatB_Yqey PF02637.13 KOS23141.1 - 0.067 12.9 1.7 0.13 11.9 1.1 1.6 1 1 0 1 1 1 0 GatB domain UcrQ PF02939.11 KOS23142.1 - 8.1e-34 115.2 0.1 9.9e-34 115.0 0.1 1.0 1 0 0 1 1 1 1 UcrQ family PRELI PF04707.9 KOS23143.1 - 2.5e-18 66.1 0.0 4.5e-16 58.8 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family DUF676 PF05057.9 KOS23144.1 - 1.8e-24 86.2 0.0 2.2e-12 46.7 0.0 2.1 2 0 0 2 2 2 2 Putative serine esterase (DUF676) PGAP1 PF07819.8 KOS23144.1 - 0.043 13.3 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 KOS23144.1 - 0.046 13.9 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain COG2 PF06148.6 KOS23145.1 - 0.14 12.0 0.4 0.55 10.1 0.1 2.1 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MscS_porin PF12795.2 KOS23145.1 - 0.18 11.0 4.7 0.089 12.1 1.4 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain RTA1 PF04479.8 KOS23146.1 - 1.2e-37 129.5 0.3 1.6e-37 129.1 0.2 1.2 1 0 0 1 1 1 1 RTA1 like protein CtnDOT_TraJ PF07863.6 KOS23146.1 - 7.4 7.1 7.6 0.51 10.8 1.0 2.1 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon Adaptin_N PF01602.15 KOS23147.1 - 4.3e-98 328.9 0.1 5.5e-98 328.5 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KOS23147.1 - 4.9e-12 45.9 5.5 0.00019 21.6 0.2 5.0 3 2 0 3 3 3 3 HEAT repeats HEAT PF02985.17 KOS23147.1 - 8.6e-08 31.6 2.0 0.08 13.0 0.0 5.2 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 KOS23147.1 - 1.1e-05 25.7 4.1 0.0094 16.4 0.0 4.8 5 0 0 5 5 5 1 HEAT-like repeat Cohesin_HEAT PF12765.2 KOS23147.1 - 3.6e-05 23.6 5.1 0.012 15.5 0.0 3.6 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.3 KOS23147.1 - 0.021 14.2 0.3 4.4 6.5 0.0 3.1 2 1 1 3 3 3 0 CLASP N terminal Cnd1 PF12717.2 KOS23147.1 - 0.025 14.4 0.0 0.26 11.1 0.0 2.5 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 SDA1 PF05285.7 KOS23147.1 - 0.68 9.1 17.2 1.1 8.4 11.9 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 KOS23147.1 - 1.1 7.1 23.4 1.6 6.5 16.2 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KOS23147.1 - 9 4.6 23.6 13 4.1 16.4 1.1 1 0 0 1 1 1 0 Daxx Family zf-C2H2 PF00096.21 KOS23148.1 - 2.8e-06 27.3 13.0 0.022 15.0 0.7 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS23148.1 - 6.5e-06 26.1 12.1 0.062 13.6 0.7 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger GET2 PF08690.5 KOS23148.1 - 0.4 9.8 2.3 0.58 9.3 1.6 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Bap31 PF05529.7 KOS23148.1 - 0.82 9.0 3.6 1.3 8.4 2.5 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like FCH PF00611.18 KOS23149.1 - 3.9e-22 78.2 0.0 3.9e-22 78.2 0.0 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KOS23149.1 - 1.8e-20 72.2 0.4 4.1e-10 39.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KOS23149.1 - 5.3e-15 54.5 0.2 1.5e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 KOS23149.1 - 3e-14 52.4 5.3 4.9e-14 51.8 3.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.6 KOS23149.1 - 0.00038 20.5 1.3 0.0017 18.5 0.4 2.3 2 0 0 2 2 2 1 Bacterial SH3 domain Atg14 PF10186.4 KOS23149.1 - 0.019 13.8 6.0 0.99 8.2 0.1 2.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 SH3_2 PF07653.12 KOS23149.1 - 0.054 13.0 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain C1_2 PF03107.11 KOS23149.1 - 0.57 10.3 7.8 0.99 9.5 5.4 1.4 1 0 0 1 1 1 0 C1 domain YlqD PF11068.3 KOS23149.1 - 3 7.8 10.8 0.66 10.0 0.7 3.0 3 0 0 3 3 3 0 YlqD protein Ax_dynein_light PF10211.4 KOS23149.1 - 8.5 6.1 19.5 0.03 14.1 3.9 2.7 3 0 0 3 3 3 0 Axonemal dynein light chain LysM PF01476.15 KOS23150.1 - 5.1e-32 109.4 3.6 5.6e-09 35.7 0.0 5.4 5 0 0 5 5 5 5 LysM domain BrkDBD PF09607.5 KOS23150.1 - 0.00054 19.4 0.1 0.19 11.3 0.0 2.5 2 0 0 2 2 2 2 Brinker DNA-binding domain Herpes_TK_C PF08465.5 KOS23150.1 - 0.055 12.9 1.5 5.3 6.6 0.1 2.6 2 0 0 2 2 2 0 Thymidine kinase from Herpesvirus C-terminal Phage_terminase PF10668.4 KOS23150.1 - 0.11 12.2 1.2 2.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Phage terminase small subunit CSS-motif PF12792.2 KOS23150.1 - 0.25 10.6 1.8 3.8 6.8 0.1 2.2 2 0 0 2 2 2 0 CSS motif domain associated with EAL UPF0203 PF05254.7 KOS23150.1 - 3.3 7.6 17.1 4.9 7.0 0.6 5.3 6 1 0 6 6 6 0 Uncharacterised protein family (UPF0203) Trypan_PARP PF05887.6 KOS23150.1 - 6.2 6.6 8.1 0.98 9.2 1.0 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) FAD_binding_4 PF01565.18 KOS23151.1 - 3.5e-26 91.3 0.8 5.5e-26 90.6 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KOS23151.1 - 1e-05 25.3 0.3 2.1e-05 24.3 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Ribosomal_60s PF00428.14 KOS23152.1 - 3e-27 94.8 15.2 3.6e-27 94.5 10.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein E1-E2_ATPase PF00122.15 KOS23153.1 - 4.6e-56 189.4 2.8 4.6e-56 189.4 1.9 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KOS23153.1 - 3.7e-40 137.4 3.6 3.7e-40 137.4 2.5 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KOS23153.1 - 5.8e-29 102.0 0.0 2.6e-28 99.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS23153.1 - 1.3e-19 69.8 0.0 3e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KOS23153.1 - 6.2e-17 62.3 0.0 1.2e-16 61.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KOS23153.1 - 1.5e-06 27.6 0.1 9.2e-06 25.0 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KOS23153.1 - 7.7e-06 25.6 1.1 7.3e-05 22.4 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.4 KOS23153.1 - 3.4 6.1 5.9 1.9 6.9 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) TTL PF03133.10 KOS23154.1 - 4.2e-55 186.7 0.0 1.7e-54 184.7 0.0 1.8 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 KOS23154.1 - 4.2e-43 146.9 0.0 5.8e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 KOS23154.1 - 0.00041 20.1 0.2 0.031 13.9 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 KOS23154.1 - 0.0012 17.6 0.0 0.004 16.0 0.0 1.7 2 0 0 2 2 2 1 YheC/D like ATP-grasp Peptidase_S8 PF00082.17 KOS23155.1 - 1.2e-15 57.4 0.0 2.3e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Ank_4 PF13637.1 KOS23155.1 - 2.9e-09 37.2 0.0 7.4e-05 23.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KOS23155.1 - 1.7e-08 34.6 0.2 0.00089 19.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KOS23155.1 - 1.5e-05 24.7 0.0 0.72 10.2 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KOS23155.1 - 0.00048 20.2 0.0 0.3 11.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KOS23155.1 - 0.0017 18.0 0.0 0.057 13.2 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat FAD_binding_3 PF01494.14 KOS23156.1 - 5.1e-19 68.5 1.2 9e-19 67.7 0.8 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KOS23156.1 - 2e-14 53.2 7.4 2.4e-07 30.0 0.4 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KOS23156.1 - 3.2e-08 33.4 0.5 9.6e-08 31.9 0.3 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KOS23156.1 - 3.5e-08 32.5 0.2 0.0031 16.2 0.0 2.4 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 KOS23156.1 - 9.2e-08 32.2 0.1 4.1e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KOS23156.1 - 1.5e-07 30.2 0.5 8.4e-07 27.7 0.5 2.0 2 1 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KOS23156.1 - 3.7e-07 29.3 2.8 2.6e-06 26.5 0.5 2.1 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KOS23156.1 - 3.8e-07 30.4 0.2 0.00012 22.4 0.1 2.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KOS23156.1 - 8.4e-07 28.4 1.0 1.1e-06 27.9 0.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KOS23156.1 - 3e-05 24.1 0.0 4.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KOS23156.1 - 4.8e-05 22.6 0.1 0.22 10.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KOS23156.1 - 8.6e-05 21.6 1.4 0.24 10.2 0.1 2.8 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 KOS23156.1 - 0.00019 21.2 1.0 0.39 10.4 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 KOS23156.1 - 0.00036 19.5 0.3 0.00061 18.7 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 KOS23156.1 - 0.0015 17.6 0.5 0.0027 16.8 0.3 1.4 1 0 0 1 1 1 1 Thi4 family SE PF08491.5 KOS23156.1 - 0.013 14.2 0.0 0.081 11.7 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase ApbA PF02558.11 KOS23156.1 - 0.035 13.5 0.6 0.068 12.6 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Abhydrolase_3 PF07859.8 KOS23157.1 - 8.4e-34 116.9 0.1 1.4e-33 116.2 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS23157.1 - 5.3e-06 26.2 0.0 7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KOS23157.1 - 0.00038 20.7 0.0 0.0009 19.5 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KOS23157.1 - 0.0017 18.2 1.0 0.0039 17.0 0.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KOS23157.1 - 0.0018 16.9 0.0 0.0097 14.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) U-box PF04564.10 KOS23158.1 - 8.9e-19 67.2 0.0 1.5e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 KOS23158.1 - 3e-18 65.2 9.0 1.1e-16 60.2 0.7 2.8 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KOS23158.1 - 3.3e-10 39.1 5.7 0.018 14.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS23158.1 - 9.6e-10 37.6 8.5 0.00032 20.3 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KOS23158.1 - 4.1e-09 35.9 4.5 0.0009 19.2 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KOS23158.1 - 3.5e-07 30.7 8.1 1.3e-05 25.6 0.3 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS23158.1 - 3.5e-06 27.2 4.6 0.0045 17.3 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KOS23158.1 - 3.3e-05 23.7 10.3 0.027 14.4 1.4 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 KOS23158.1 - 7.3e-05 22.5 0.6 7.3e-05 22.5 0.4 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KOS23158.1 - 0.00072 19.9 0.2 0.00072 19.9 0.1 4.6 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KOS23158.1 - 0.0025 17.4 1.2 4 7.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 KOS23158.1 - 0.029 14.4 2.0 0.051 13.6 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KOS23158.1 - 0.05 13.7 0.7 0.44 10.7 0.3 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 MC1 PF05854.6 KOS23158.1 - 0.077 12.9 1.0 0.14 12.1 0.3 1.7 1 1 1 2 2 2 0 Non-histone chromosomal protein MC1 Alkyl_sulf_dimr PF14863.1 KOS23158.1 - 0.11 12.7 1.2 0.27 11.4 0.0 2.2 1 1 2 3 3 3 0 Alkyl sulfatase dimerisation TPR_8 PF13181.1 KOS23158.1 - 0.16 11.7 3.4 12 5.9 0.2 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat HTH_32 PF13565.1 KOS23158.1 - 0.74 10.6 4.1 35 5.2 0.0 2.9 2 1 0 2 2 2 0 Homeodomain-like domain TPR_6 PF13174.1 KOS23158.1 - 2.7 8.6 5.3 23 5.7 0.6 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat Mg_trans_NIPA PF05653.9 KOS23159.1 - 3.5e-93 311.8 23.9 4.9e-93 311.3 16.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KOS23159.1 - 4.5e-07 30.0 4.5 4.5e-07 30.0 3.1 3.0 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KOS23159.1 - 4.7e-06 26.6 7.8 4.7e-06 26.6 5.4 2.8 3 1 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 KOS23159.1 - 4 6.1 18.7 8.8 5.0 13.0 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) UPF0370 PF13980.1 KOS23159.1 - 9.7 6.0 8.1 11 5.9 0.7 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) DHO_dh PF01180.16 KOS23160.1 - 6.4e-63 212.4 0.0 8.7e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 KOS23160.1 - 9.6e-05 21.7 0.6 0.2 10.8 0.2 2.3 2 0 0 2 2 2 2 PcrB family Usp PF00582.21 KOS23160.1 - 0.024 14.8 0.2 0.053 13.7 0.2 1.5 1 0 0 1 1 1 0 Universal stress protein family FMN_dh PF01070.13 KOS23160.1 - 1.3 7.7 8.1 0.03 13.1 0.7 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase SBF PF01758.11 KOS23161.1 - 1.9e-48 164.3 13.1 7e-48 162.5 8.3 2.2 2 0 0 2 2 2 1 Sodium Bile acid symporter family Ank_2 PF12796.2 KOS23162.1 - 6.3e-122 398.2 16.2 1e-17 64.2 0.0 10.7 1 1 8 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 KOS23162.1 - 9.2e-83 268.2 29.1 2.5e-06 27.0 0.0 20.2 19 3 0 19 19 19 17 Ankyrin repeat Ank_4 PF13637.1 KOS23162.1 - 6.6e-73 239.9 13.6 4e-08 33.5 0.0 14.8 6 6 9 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS23162.1 - 3.2e-63 203.3 9.4 0.00045 20.1 0.0 18.0 18 0 0 18 18 18 15 Ankyrin repeat Ank_5 PF13857.1 KOS23162.1 - 1.1e-50 168.4 29.8 5.8e-10 39.0 0.1 14.3 7 4 7 14 14 14 12 Ankyrin repeats (many copies) ZZ PF00569.12 KOS23162.1 - 0.0067 15.9 3.2 0.013 15.0 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Glyco_transf_25 PF01755.12 KOS23165.1 - 0.00041 20.0 0.0 0.78 9.3 0.0 2.8 3 0 0 3 3 3 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Cellulase PF00150.13 KOS23166.1 - 3.9e-48 164.0 0.1 5.4e-48 163.6 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KOS23166.1 - 1.2e-24 85.6 27.3 1.2e-13 50.4 8.3 3.3 4 0 0 4 4 4 2 Fungal cellulose binding domain Glyco_hydro_1 PF00232.13 KOS23166.1 - 0.015 13.4 0.1 0.023 12.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 FAD_binding_4 PF01565.18 KOS23167.1 - 2.1e-10 40.2 2.7 2.1e-10 40.2 1.8 1.9 3 0 0 3 3 3 1 FAD binding domain Ank_2 PF12796.2 KOS23169.1 - 3.9e-15 55.9 0.5 6.2e-06 26.4 0.2 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KOS23169.1 - 3.7e-14 52.7 2.7 6.6e-08 32.8 0.1 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 KOS23169.1 - 9.1e-13 47.3 1.4 1.2e-05 24.8 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KOS23169.1 - 1.5e-12 47.3 0.2 4.7e-05 23.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS23169.1 - 4e-11 42.0 0.7 0.00033 20.6 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 KOS23169.1 - 8e-05 22.2 0.3 0.0005 19.6 0.1 2.2 2 1 0 2 2 2 1 KilA-N domain Cast PF10174.4 KOS23169.1 - 0.00023 19.3 1.3 0.00035 18.7 0.9 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Atg14 PF10186.4 KOS23169.1 - 0.45 9.4 5.3 0.79 8.6 3.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Macoilin PF09726.4 KOS23169.1 - 1.6 6.9 7.7 2.3 6.3 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein FYVE PF01363.16 KOS23170.1 - 5.4e-24 83.8 17.6 5.1e-17 61.5 4.2 3.1 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 KOS23170.1 - 0.00047 20.2 6.8 0.011 15.8 0.0 2.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 KOS23170.1 - 0.0013 18.5 1.8 0.0013 18.5 1.3 3.5 3 1 0 3 3 3 1 AN1-like Zinc finger Rbsn PF11464.3 KOS23170.1 - 0.0076 15.7 0.2 0.021 14.3 0.1 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain UPF0547 PF10571.4 KOS23170.1 - 0.0078 15.8 0.1 1 9.1 0.0 4.0 4 1 0 4 4 4 1 Uncharacterised protein family UPF0547 CK_II_beta PF01214.13 KOS23170.1 - 0.1 12.0 0.1 0.28 10.6 0.1 1.7 1 0 0 1 1 1 0 Casein kinase II regulatory subunit IncA PF04156.9 KOS23170.1 - 0.44 10.1 6.1 0.31 10.6 0.6 2.8 3 0 0 3 3 3 0 IncA protein TMF_TATA_bd PF12325.3 KOS23170.1 - 0.54 10.0 8.5 0.15 11.7 2.6 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KOS23170.1 - 0.69 9.7 4.9 16 5.3 0.0 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 KOS23170.1 - 1.5 7.7 4.3 25 3.8 3.4 2.3 1 1 0 1 1 1 0 Autophagy protein Apg6 bZIP_1 PF00170.16 KOS23170.1 - 2.5 8.1 0.0 2.5 8.1 0.0 3.3 3 0 0 3 3 3 0 bZIP transcription factor zf-DHHC PF01529.15 KOS23170.1 - 5.4 6.3 6.9 0.24 10.8 0.3 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase TPK_B1_binding PF04265.9 KOS23171.1 - 7.1e-24 83.3 0.1 1.2e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 KOS23171.1 - 2e-22 79.0 0.0 2.9e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain DUF2112 PF09885.4 KOS23171.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) V-SNARE_C PF12352.3 KOS23172.1 - 1.5e-12 47.3 0.1 3.1e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KOS23172.1 - 0.00015 21.4 0.0 0.00033 20.2 0.0 1.5 1 0 0 1 1 1 1 Sec20 DUF4341 PF14241.1 KOS23172.1 - 0.023 14.3 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4341) NAD_binding_7 PF13241.1 KOS23173.1 - 7.8e-31 106.3 0.1 1.3e-30 105.6 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KOS23173.1 - 4e-26 90.1 0.0 5.9e-26 89.5 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KOS23173.1 - 1.1e-09 37.0 0.0 1.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Exonuc_VII_L PF02601.10 KOS23173.1 - 0.026 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TrkA_N PF02254.13 KOS23173.1 - 0.078 12.9 0.2 0.18 11.7 0.2 1.7 1 1 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 KOS23173.1 - 0.23 11.2 0.9 0.31 10.8 0.1 1.6 1 1 1 2 2 2 0 ThiF family CHCH PF06747.8 KOS23174.1 - 2.1e-07 30.6 5.5 3.2e-07 30.0 3.8 1.3 1 0 0 1 1 1 1 CHCH domain VirC2 PF07181.6 KOS23174.1 - 5.8 6.2 9.1 3 7.2 4.2 2.0 2 0 0 2 2 2 0 VirC2 protein PTR2 PF00854.16 KOS23175.1 - 1.5e-41 142.4 7.2 1.2e-38 132.8 5.0 2.2 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 KOS23175.1 - 9.9e-05 21.2 25.0 0.00057 18.6 16.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 KOS23176.1 - 2.1e-05 23.4 6.7 2.1e-05 23.4 4.6 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.11 KOS23177.1 - 4.2e-51 173.7 24.0 4.2e-51 173.7 16.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS23177.1 - 1.9e-12 46.4 9.8 1.9e-12 46.4 6.8 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KOS23177.1 - 4e-07 28.6 4.5 6.2e-07 27.9 3.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KOS23177.1 - 0.00011 20.5 3.4 0.00011 20.5 2.4 2.1 3 0 0 3 3 3 1 Transmembrane secretion effector ATG22 PF11700.3 KOS23177.1 - 0.0018 16.8 18.4 0.032 12.7 3.1 3.3 2 2 1 3 3 3 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 KOS23177.1 - 0.003 17.3 2.4 0.62 9.8 0.4 3.0 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.15 KOS23177.1 - 0.0092 14.0 0.6 0.028 12.4 0.4 1.9 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF791 PF05631.9 KOS23177.1 - 0.011 14.3 1.5 0.022 13.4 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF791) DUF3353 PF11833.3 KOS23177.1 - 0.04 13.3 5.2 0.13 11.7 3.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) TMEM171 PF15471.1 KOS23177.1 - 0.51 9.0 2.3 1.3 7.7 1.6 1.7 1 0 0 1 1 1 0 Transmembrane protein family 171 p450 PF00067.17 KOS23178.1 - 5.8e-51 173.4 0.0 1.3e-50 172.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Glutaredoxin PF00462.19 KOS23179.1 - 1.3e-16 60.3 0.0 2.1e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Glyco_hydro_3_C PF01915.17 KOS23180.1 - 1.3e-52 178.5 0.0 2e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 KOS23180.1 - 4.7e-41 140.7 0.0 6.1e-29 100.9 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 KOS23180.1 - 6.9e-14 51.5 0.1 1.5e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KOS23180.1 - 1.5e-07 31.1 0.0 3.8e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 PA14 domain ADH_zinc_N_2 PF13602.1 KOS23181.1 - 1.5e-21 77.6 0.0 4e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KOS23181.1 - 2.6e-11 43.1 0.1 6.3e-11 41.9 0.1 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KOS23181.1 - 5.3e-11 42.2 1.1 1.2e-09 37.9 0.0 2.9 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.16 KOS23181.1 - 0.028 14.3 0.2 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit DUF3335 PF11814.3 KOS23181.1 - 0.044 12.9 0.4 4.1 6.4 0.1 2.1 2 0 0 2 2 2 0 Peptidase_C39 like family DOT1 PF08123.8 KOS23181.1 - 0.18 11.1 1.4 0.58 9.4 0.7 1.7 1 1 1 2 2 2 0 Histone methylation protein DOT1 adh_short PF00106.20 KOS23182.1 - 1.2e-14 54.5 0.0 1.6e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KOS23182.1 - 5.1e-07 29.7 0.0 0.022 14.5 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS23182.1 - 0.011 15.3 0.0 0.026 14.2 0.0 1.5 2 0 0 2 2 2 0 KR domain Epimerase PF01370.16 KOS23182.1 - 0.037 13.4 0.0 1 8.7 0.0 2.4 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family Ank_2 PF12796.2 KOS23183.1 - 9.4e-87 285.4 25.2 6.1e-17 61.7 0.7 7.6 3 2 5 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 KOS23183.1 - 2.4e-52 172.2 21.7 4.1e-07 29.4 0.0 14.0 14 0 0 14 14 14 11 Ankyrin repeat Ank_4 PF13637.1 KOS23183.1 - 1.1e-40 137.3 8.3 7.3e-08 32.7 0.0 11.0 5 4 7 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS23183.1 - 2.1e-37 123.3 13.2 0.00069 19.6 0.0 14.3 14 0 0 14 14 14 9 Ankyrin repeat Ank_5 PF13857.1 KOS23183.1 - 2.1e-32 110.4 18.3 7.8e-07 29.1 0.0 11.1 4 4 9 13 13 13 8 Ankyrin repeats (many copies) OPT PF03169.10 KOS23184.1 - 2.6e-153 511.7 47.2 2.9e-153 511.5 32.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CCSMST1 PF15013.1 KOS23184.1 - 6 6.8 6.6 11 6.0 1.5 3.4 2 0 0 2 2 2 0 CCSMST1 family DUF2422 PF10337.4 KOS23185.1 - 1e-87 294.8 8.9 6e-87 292.3 2.2 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KOS23185.1 - 2.8e-55 187.4 2.2 5.3e-54 183.2 0.1 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KOS23185.1 - 1.6e-08 34.5 11.2 1.6e-08 34.5 7.8 3.5 2 2 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 KOS23185.1 - 0.00045 18.9 6.5 0.054 12.1 3.7 2.5 1 1 1 2 2 2 2 Aluminium activated malate transporter Ubiquitin_3 PF14836.1 KOS23185.1 - 0.0044 16.6 0.0 0.054 13.1 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-like domain Mod_r PF07200.8 KOS23185.1 - 0.053 13.4 0.6 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FEZ PF07763.8 KOS23185.1 - 0.15 11.7 1.0 0.26 10.9 0.3 1.6 2 0 0 2 2 2 0 FEZ-like protein Zip PF02535.17 KOS23186.1 - 2.5e-52 177.8 0.5 2.9e-52 177.6 0.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter FAD_binding_3 PF01494.14 KOS23187.1 - 3.7e-12 45.9 0.4 1.6e-10 40.6 0.0 2.6 2 1 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 KOS23187.1 - 0.0018 18.0 0.0 0.48 10.1 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KOS23187.1 - 0.011 15.7 0.0 0.09 12.8 0.0 2.6 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KOS23187.1 - 0.015 14.1 1.0 0.064 12.1 0.1 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KOS23187.1 - 0.046 13.5 0.0 0.095 12.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KOS23187.1 - 0.047 13.2 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 KOS23187.1 - 0.1 11.4 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase MIP PF00230.15 KOS23188.1 - 2e-40 138.6 13.4 2.3e-40 138.4 9.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein DHHA1 PF02272.14 KOS23189.1 - 0.017 14.7 0.1 0.066 12.9 0.0 1.9 2 0 0 2 2 2 0 DHHA1 domain ERG4_ERG24 PF01222.12 KOS23190.1 - 3.6e-149 496.9 1.3 4.1e-149 496.7 0.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KOS23190.1 - 0.0004 19.7 0.0 0.00099 18.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) MitoNEET_N PF10660.4 KOS23190.1 - 0.072 12.9 0.2 11 5.9 0.0 2.8 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus IncA PF04156.9 KOS23190.1 - 0.11 12.0 0.7 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 IncA protein DAO PF01266.19 KOS23191.1 - 1.6e-25 89.8 3.1 2.1e-25 89.4 2.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KOS23191.1 - 0.0054 15.6 0.0 0.0083 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KOS23191.1 - 0.0098 15.8 0.5 0.025 14.5 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KOS23191.1 - 0.014 14.4 0.2 0.03 13.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KOS23191.1 - 0.13 12.7 0.8 0.34 11.3 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Isochorismatase PF00857.15 KOS23191.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Isochorismatase family DUF1669 PF07894.7 KOS23191.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) RGS PF00615.14 KOS23192.1 - 3.6e-34 117.3 0.0 1.4e-33 115.4 0.0 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 KOS23192.1 - 2.5e-23 81.6 0.0 1.1e-18 66.7 0.0 2.9 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) 2-Hacid_dh PF00389.25 KOS23192.1 - 0.059 12.8 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain CDC73 PF05179.9 KOS23193.1 - 2.1e-46 158.4 0.0 4.4e-46 157.4 0.0 1.4 1 1 1 2 2 2 1 RNA pol II accessory factor, Cdc73 family HAD PF12710.2 KOS23194.1 - 3.2e-15 56.8 0.0 4.1e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KOS23194.1 - 1.9e-05 24.9 0.0 0.00012 22.3 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KOS23194.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.5 1 1 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) She9_MDM33 PF05546.6 KOS23195.1 - 7.5e-79 264.1 4.2 7.5e-79 264.1 2.9 1.6 2 0 0 2 2 2 1 She9 / Mdm33 family BCAS2 PF05700.6 KOS23195.1 - 0.006 16.0 0.9 0.0091 15.4 0.6 1.3 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) LAG1-DNAbind PF09271.6 KOS23195.1 - 0.081 13.4 0.2 0.15 12.5 0.2 1.4 1 0 0 1 1 1 0 LAG1, DNA binding DUF4398 PF14346.1 KOS23195.1 - 9.5 6.3 12.2 0.45 10.5 1.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) ALG3 PF05208.8 KOS23196.1 - 1.5e-141 471.8 14.5 1.8e-141 471.6 10.0 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.14 KOS23197.1 - 1.4e-10 40.3 0.0 3.3e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 HR1 PF02185.11 KOS23198.1 - 7.6e-29 99.2 18.9 7.1e-17 60.9 2.5 3.0 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.17 KOS23198.1 - 6.4e-12 45.0 11.2 9.5e-12 44.4 7.8 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KOS23198.1 - 0.0014 18.2 6.8 0.0022 17.6 4.7 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD PF00628.24 KOS23198.1 - 0.021 14.5 8.0 0.037 13.7 5.6 1.4 1 0 0 1 1 1 0 PHD-finger Acyl-CoA_dh_1 PF00441.19 KOS23199.1 - 4.1e-38 130.8 5.2 8.1e-38 129.8 3.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KOS23199.1 - 3.1e-30 105.0 2.6 3.9e-30 104.7 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KOS23199.1 - 1.2e-16 59.9 0.1 2.8e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KOS23199.1 - 1.2e-15 57.9 2.4 1.2e-15 57.9 1.6 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KOS23199.1 - 0.0043 16.4 0.1 0.021 14.2 0.1 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF3184 PF11380.3 KOS23199.1 - 0.029 12.3 0.2 0.044 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) LtrA PF06772.6 KOS23200.1 - 1.6e-11 43.7 20.0 2.6e-11 43.0 13.9 1.3 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) MliC PF09864.4 KOS23201.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme DUF2793 PF10983.3 KOS23201.1 - 0.16 11.7 0.3 0.29 10.9 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2793) Glyco_hydro_3 PF00933.16 KOS23202.1 - 3.8e-82 275.6 0.0 5.3e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KOS23202.1 - 1.2e-42 146.0 0.8 4.1e-41 140.9 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KOS23202.1 - 3.8e-23 81.1 0.1 7e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF1746 PF08508.5 KOS23203.1 - 0.046 13.6 0.1 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1746) DUF4440 PF14534.1 KOS23204.1 - 2.2e-05 24.6 0.0 2.5e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Band_7 PF01145.20 KOS23205.1 - 1.9e-13 50.6 0.0 1.9e-13 50.6 0.0 3.5 2 2 0 3 3 3 1 SPFH domain / Band 7 family adh_short PF00106.20 KOS23207.1 - 7.6e-06 25.9 0.8 8.5e-06 25.7 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase AdoHcyase_NAD PF00670.16 KOS23207.1 - 1e-05 25.4 0.4 1e-05 25.4 0.3 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 KOS23207.1 - 2.7e-05 23.9 0.7 2.8e-05 23.8 0.5 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KOS23207.1 - 0.00072 19.6 0.3 0.00084 19.4 0.2 1.0 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase PALP PF00291.20 KOS23207.1 - 0.0038 16.5 0.3 0.0041 16.4 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme F420_oxidored PF03807.12 KOS23207.1 - 0.0065 16.8 1.1 0.0075 16.6 0.8 1.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AAA_30 PF13604.1 KOS23207.1 - 0.042 13.4 1.2 0.049 13.2 0.9 1.0 1 0 0 1 1 1 0 AAA domain THF_DHG_CYH_C PF02882.14 KOS23207.1 - 0.13 11.3 0.1 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AlaDh_PNT_C PF01262.16 KOS23207.1 - 0.34 10.4 2.4 0.6 9.6 1.7 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RicinB_lectin_2 PF14200.1 KOS23208.1 - 9.9e-17 61.2 0.2 4e-14 52.8 0.1 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KOS23208.1 - 1e-06 28.7 0.0 0.024 14.6 0.0 2.1 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain DUF1237 PF06824.6 KOS23210.1 - 4.9e-141 470.1 0.0 5.7e-141 469.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Phage_NinH PF06322.6 KOS23210.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Phage NinH protein Bac_rhamnosid PF05592.6 KOS23210.1 - 0.063 11.4 0.1 0.099 10.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase Peptidase_A4 PF01828.12 KOS23211.1 - 3.2e-74 248.5 5.4 3.7e-74 248.2 3.7 1.0 1 0 0 1 1 1 1 Peptidase A4 family Fringe PF02434.11 KOS23212.1 - 1.3e-06 27.8 0.0 2.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 KOS23212.1 - 0.0019 17.4 0.0 0.005 16.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF604 BRO1 PF03097.13 KOS23213.1 - 1.4e-105 353.1 0.0 2.2e-105 352.4 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KOS23213.1 - 1.8e-75 253.6 2.9 1.8e-75 253.6 2.0 1.9 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV R3H-assoc PF13902.1 KOS23213.1 - 0.045 13.7 1.5 0.12 12.3 1.1 1.7 1 0 0 1 1 1 0 R3H-associated N-terminal domain Transp_cyt_pur PF02133.10 KOS23214.1 - 4.6e-153 509.9 37.7 5.3e-153 509.7 26.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin IBN_N PF03810.14 KOS23215.1 - 8.8e-12 44.7 0.9 1.2e-09 37.8 0.1 3.1 2 1 0 2 2 2 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.10 KOS23215.1 - 0.003 15.9 0.0 0.0052 15.1 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus HEAT_2 PF13646.1 KOS23215.1 - 0.0058 16.8 7.7 1.2 9.5 0.0 4.8 4 1 1 5 5 5 2 HEAT repeats Xpo1 PF08389.7 KOS23215.1 - 0.018 14.9 0.0 0.35 10.7 0.0 3.0 2 0 0 2 2 2 0 Exportin 1-like protein DUF4611 PF15387.1 KOS23215.1 - 0.025 14.7 1.5 0.061 13.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PI31_Prot_N PF11566.3 KOS23216.1 - 1.8e-21 76.3 0.0 2.1e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KOS23216.1 - 1.2e-15 57.9 16.3 1.2e-15 57.9 11.3 2.7 3 0 0 3 3 3 1 PI31 proteasome regulator Reo_sigmaC PF04582.7 KOS23217.1 - 0.031 13.4 0.2 0.061 12.4 0.1 1.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein 2-Hacid_dh_C PF02826.14 KOS23218.1 - 3.5e-55 185.9 0.2 9.3e-55 184.5 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KOS23218.1 - 4.2e-27 94.2 0.0 5.5e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KOS23218.1 - 2.8e-06 27.2 0.0 4.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 KOS23218.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 KOS23218.1 - 0.029 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_C PF01262.16 KOS23218.1 - 0.044 13.3 0.3 0.69 9.4 0.2 2.2 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 KOS23218.1 - 0.092 13.0 0.0 0.28 11.5 0.0 1.9 1 0 0 1 1 1 0 XdhC Rossmann domain Pyr_redox_3 PF13738.1 KOS23220.1 - 6e-10 39.5 0.1 1.7e-06 28.2 0.1 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KOS23220.1 - 1.3e-09 37.4 0.0 2.1e-07 30.1 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KOS23220.1 - 4.8e-07 29.6 0.2 0.013 15.2 0.0 2.5 1 1 1 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KOS23220.1 - 7e-05 22.7 0.0 0.00017 21.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KOS23220.1 - 0.00016 19.9 0.0 0.065 11.4 0.0 2.9 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.22 KOS23220.1 - 0.014 15.8 2.8 1.4 9.3 0.1 3.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS23220.1 - 0.034 14.1 1.0 0.12 12.4 0.1 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KOS23220.1 - 0.049 12.7 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 KOS23220.1 - 0.056 12.4 0.2 0.094 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KOS23220.1 - 0.15 10.4 0.1 1.8 6.9 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Beta_helix PF13229.1 KOS23221.1 - 1.8e-05 24.5 29.1 0.00011 21.9 18.1 3.0 2 1 0 2 2 2 1 Right handed beta helix region B_lectin PF01453.19 KOS23221.1 - 0.00076 19.3 0.2 0.0024 17.7 0.2 1.9 1 0 0 1 1 1 1 D-mannose binding lectin HORMA PF02301.13 KOS23222.1 - 5.3e-16 58.7 0.0 8.2e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 HORMA domain Alpha_GJ PF03229.8 KOS23222.1 - 0.033 14.5 1.2 0.033 14.5 0.9 2.9 2 1 0 3 3 3 0 Alphavirus glycoprotein J RhoGEF PF00621.15 KOS23223.1 - 2.6e-25 89.3 0.5 6.5e-25 88.0 0.4 1.6 1 0 0 1 1 1 1 RhoGEF domain Noelin-1 PF12308.3 KOS23223.1 - 0.089 12.5 1.1 0.34 10.7 0.7 2.0 1 0 0 1 1 1 0 Neurogenesis glycoprotein KH_1 PF00013.24 KOS23224.1 - 7.5e-10 38.3 0.0 3.3e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 KOS23224.1 - 2.4e-07 30.2 0.9 1.8e-05 24.2 0.0 3.0 3 0 0 3 3 3 1 KH domain Harakiri PF15196.1 KOS23224.1 - 1 9.6 5.6 29 4.9 0.0 3.0 2 1 1 3 3 3 0 Activator of apoptosis harakiri DUF974 PF06159.8 KOS23225.1 - 4.3e-67 226.1 0.0 6.5e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Sporozoite_P67 PF05642.6 KOS23225.1 - 0.077 10.8 2.2 0.16 9.7 1.5 1.5 1 1 0 1 1 1 0 Sporozoite P67 surface antigen OTCace_N PF02729.16 KOS23226.1 - 3.4e-41 140.2 0.0 4.7e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 KOS23226.1 - 1.1e-36 126.0 0.0 1.6e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ALS_ss_C PF10369.4 KOS23227.1 - 4.3e-18 64.8 0.0 5.1e-17 61.3 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 KOS23227.1 - 7.3e-12 44.5 0.1 1.3e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KOS23227.1 - 6e-09 35.5 0.0 1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 ACT domain SART-1 PF03343.8 KOS23228.1 - 6.1e-150 500.5 65.7 7e-150 500.3 45.5 1.0 1 0 0 1 1 1 1 SART-1 family DUF3712 PF12505.3 KOS23229.1 - 0.00038 20.4 0.0 0.0036 17.3 0.0 2.7 3 1 0 3 3 3 1 Protein of unknown function (DUF3712) SNAP PF14938.1 KOS23230.1 - 8.6e-74 248.2 11.4 9.6e-74 248.0 7.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KOS23230.1 - 4.4e-06 26.5 16.9 0.00066 19.5 2.9 3.2 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 KOS23230.1 - 0.00012 21.6 16.3 0.38 10.6 0.2 5.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KOS23230.1 - 0.00081 19.6 9.3 0.35 11.4 0.1 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KOS23230.1 - 0.0012 18.6 15.2 0.59 10.1 0.3 5.7 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KOS23230.1 - 0.013 15.1 15.1 0.16 11.6 2.2 3.3 1 1 3 4 4 4 0 TPR repeat TPR_14 PF13428.1 KOS23230.1 - 0.015 15.8 19.0 0.45 11.3 0.4 5.5 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 KOS23230.1 - 0.017 15.8 19.2 0.11 13.2 4.2 4.1 2 2 2 4 4 4 0 Tetratricopeptide repeat DUF3347 PF11827.3 KOS23230.1 - 0.035 14.1 4.7 0.057 13.4 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) TPR_19 PF14559.1 KOS23230.1 - 0.12 12.7 14.5 0.22 11.9 1.9 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KOS23230.1 - 0.15 11.8 6.7 0.2 11.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Spore_II_R PF09551.5 KOS23230.1 - 0.22 11.5 3.3 1.6 8.7 0.3 2.4 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) Spatacsin_C PF14649.1 KOS23230.1 - 0.22 10.3 5.6 1 8.1 3.4 2.2 1 1 0 1 1 1 0 Spatacsin C-terminus HHH_8 PF14716.1 KOS23230.1 - 1.4 9.1 9.1 0.65 10.2 1.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix domain DUF4375 PF14300.1 KOS23230.1 - 3.3 7.7 13.5 0.12 12.3 1.7 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4375) FlaF PF07309.6 KOS23230.1 - 6 6.7 7.0 7.5 6.4 3.1 2.1 1 1 1 2 2 2 0 Flagellar protein FlaF Glyco_hydro_15 PF00723.16 KOS23231.1 - 2.7e-98 329.4 0.0 3.2e-98 329.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KOS23231.1 - 9.4e-29 98.8 0.2 2.2e-28 97.6 0.2 1.7 1 0 0 1 1 1 1 Starch binding domain DENN PF02141.16 KOS23233.1 - 1.2e-57 194.6 0.0 1.9e-57 193.9 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KOS23233.1 - 5.4e-17 61.5 0.0 1.1e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 KOS23233.1 - 7.4e-17 61.1 0.3 1.3e-16 60.3 0.2 1.4 1 0 0 1 1 1 1 dDENN domain C1_1 PF00130.17 KOS23233.1 - 0.0054 16.4 4.6 0.011 15.4 3.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 KOS23233.1 - 0.016 14.8 3.9 0.042 13.5 2.7 1.7 1 0 0 1 1 1 0 PHD-finger SPA PF08616.5 KOS23233.1 - 0.044 13.4 0.1 0.086 12.5 0.1 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis C1_3 PF07649.7 KOS23233.1 - 0.097 12.7 3.3 0.2 11.7 2.3 1.6 1 0 0 1 1 1 0 C1-like domain Prok-RING_1 PF14446.1 KOS23233.1 - 0.12 12.1 4.9 0.22 11.2 3.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.11 KOS23233.1 - 0.24 11.5 4.3 0.49 10.5 3.0 1.6 1 0 0 1 1 1 0 C1 domain zf-RING_2 PF13639.1 KOS23233.1 - 1.1 9.1 3.5 2.5 8.0 2.4 1.6 1 0 0 1 1 1 0 Ring finger domain FDF PF09532.5 KOS23233.1 - 1.7 9.2 3.9 6 7.4 2.7 2.0 1 1 0 1 1 1 0 FDF domain DUF726 PF05277.7 KOS23234.1 - 2.7e-86 289.6 0.0 3e-86 289.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 KOS23234.1 - 0.0012 18.7 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS23234.1 - 0.017 14.8 0.0 0.044 13.5 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS23234.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold MRP-L20 PF12824.2 KOS23235.1 - 8.9e-48 162.3 2.9 1.1e-47 162.0 2.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 KOS23235.1 - 0.02 14.7 0.7 0.039 13.7 0.1 1.8 2 0 0 2 2 2 0 Neugrin Not3 PF04065.10 KOS23236.1 - 8.3e-100 332.8 21.4 1.2e-99 332.2 14.8 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KOS23236.1 - 6.7e-40 136.0 8.9 6.7e-40 136.0 6.1 2.3 2 1 1 3 3 3 1 NOT2 / NOT3 / NOT5 family DUF1192 PF06698.6 KOS23236.1 - 0.0045 16.7 1.2 0.017 14.9 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) DUF2373 PF10180.4 KOS23236.1 - 0.0074 15.8 3.2 0.015 14.8 2.2 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 KOS23236.1 - 0.029 14.2 4.0 0.082 12.8 0.3 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Syntaxin PF00804.20 KOS23236.1 - 0.3 11.2 15.7 0.091 12.9 3.4 2.9 3 0 0 3 3 3 0 Syntaxin Snapin_Pallidin PF14712.1 KOS23236.1 - 0.36 11.1 7.8 2.9 8.2 0.1 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Poty_PP PF08440.5 KOS23236.1 - 0.43 9.6 4.9 0.12 11.4 1.0 1.7 2 0 0 2 2 2 0 Potyviridae polyprotein 4HB_MCP_1 PF12729.2 KOS23236.1 - 1.4 8.1 12.8 4.5 6.5 5.2 2.4 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Syntaxin_2 PF14523.1 KOS23236.1 - 2.8 8.0 11.1 0.11 12.4 2.2 2.7 3 0 0 3 3 3 0 Syntaxin-like protein DUF641 PF04859.7 KOS23237.1 - 0.0082 15.9 0.4 0.038 13.7 0.2 1.9 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) BCS1_N PF08740.6 KOS23237.1 - 0.051 13.1 0.1 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 BCS1 N terminal FUSC PF04632.7 KOS23237.1 - 3.8 5.8 11.7 6.1 5.1 8.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family MDMPI_N PF11716.3 KOS23237.1 - 8.4 6.8 17.0 1.7 9.0 2.7 2.5 1 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Tyr_Deacylase PF02580.11 KOS23238.1 - 6.2e-49 165.7 0.1 6.9e-49 165.5 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase HypA PF01155.14 KOS23239.1 - 0.15 11.7 3.6 0.3 10.7 2.5 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF3357 PF11837.3 KOS23240.1 - 0.14 12.0 0.3 0.16 11.8 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) CENP-B_dimeris PF09026.5 KOS23240.1 - 0.2 11.9 8.6 0.24 11.6 5.9 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.6 KOS23240.1 - 0.42 8.4 4.6 0.43 8.3 3.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 KOS23240.1 - 0.73 7.6 3.0 0.71 7.7 2.1 1.0 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 KOS23240.1 - 0.82 10.0 7.9 0.91 9.8 5.5 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 KOS23240.1 - 1.2 8.7 4.8 1.2 8.7 3.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 KOS23240.1 - 1.6 7.3 10.7 1.4 7.5 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PYST-C1 PF09690.5 KOS23240.1 - 1.8 8.2 10.4 2.2 8.0 7.2 1.1 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) TFIIF_alpha PF05793.7 KOS23240.1 - 2.2 6.5 6.9 2 6.6 4.8 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4611 PF15387.1 KOS23240.1 - 2.8 8.1 7.1 3.2 7.9 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 KOS23240.1 - 6.9 6.1 9.4 7.7 6.0 6.5 1.1 1 0 0 1 1 1 0 Nucleoplasmin DUF3245 PF11595.3 KOS23240.1 - 9 6.5 6.6 10 6.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Cg6151-P PF10233.4 KOS23241.1 - 9.7e-37 125.4 13.3 1.2e-36 125.1 9.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Cytochrom_B558a PF05038.8 KOS23241.1 - 0.73 9.4 7.1 2.4 7.7 4.9 1.7 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit AAA_12 PF13087.1 KOS23242.1 - 3.2e-52 176.8 0.0 6.7e-52 175.7 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 KOS23242.1 - 1.2e-38 133.0 0.4 4.4e-19 69.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 KOS23242.1 - 3.5e-14 52.8 0.0 8.8e-14 51.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Dna2 PF08696.6 KOS23242.1 - 1.1e-11 44.5 0.5 2e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_19 PF13245.1 KOS23242.1 - 1.8e-10 40.4 0.3 4.1e-10 39.2 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain Cas_Cas4 PF01930.12 KOS23242.1 - 1.6e-09 37.8 0.1 3.4e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 KOS23242.1 - 8.1e-08 32.0 0.8 0.12 11.8 0.1 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase MobB PF03205.9 KOS23242.1 - 2e-05 24.3 0.2 7.6e-05 22.4 0.1 2.0 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B Helicase_RecD PF05127.9 KOS23242.1 - 3.8e-05 23.3 0.0 0.0001 22.0 0.0 1.7 1 1 0 1 1 1 1 Helicase PIF1 PF05970.9 KOS23242.1 - 0.0002 20.4 0.3 0.00084 18.3 0.2 1.9 1 1 0 1 1 1 1 PIF1-like helicase CbiA PF01656.18 KOS23242.1 - 0.00065 19.1 0.1 0.002 17.5 0.1 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 KOS23242.1 - 0.0011 18.3 0.2 0.0021 17.5 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KOS23242.1 - 0.0015 17.9 0.7 0.022 14.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain UvrD-helicase PF00580.16 KOS23242.1 - 0.0037 16.6 0.1 0.0074 15.6 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 KOS23242.1 - 0.0061 16.7 0.0 0.091 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KOS23242.1 - 0.011 14.6 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 KOS23242.1 - 0.013 15.3 0.1 0.026 14.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 Miro PF08477.8 KOS23242.1 - 0.014 15.9 0.0 0.045 14.2 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 KOS23242.1 - 0.018 15.0 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 KOS23242.1 - 0.02 14.7 0.1 0.057 13.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KOS23242.1 - 0.031 13.7 0.0 0.092 12.2 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KOS23242.1 - 0.034 13.5 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 KOS23242.1 - 0.036 13.7 0.3 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 KOS23242.1 - 0.047 12.5 0.1 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.7 KOS23242.1 - 0.055 12.5 0.1 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ArgK PF03308.11 KOS23242.1 - 0.056 12.2 0.1 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 KOS23242.1 - 0.066 12.9 0.3 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 NTPase ResIII PF04851.10 KOS23242.1 - 0.075 12.8 0.5 0.21 11.3 0.3 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit cobW PF02492.14 KOS23242.1 - 0.079 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UvrD_C_2 PF13538.1 KOS23242.1 - 0.099 12.7 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.24 KOS23242.1 - 0.099 12.8 0.2 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.4 KOS23242.1 - 0.12 11.0 0.2 0.2 10.2 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SelR PF01641.13 KOS23244.1 - 2.3e-50 169.4 0.0 2.7e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 KOS23244.1 - 0.013 15.3 2.5 1.1 9.1 0.1 2.4 2 1 0 2 2 2 0 Double zinc ribbon DUF2296 PF10058.4 KOS23244.1 - 0.094 12.4 0.5 0.54 10.0 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Yippee-Mis18 PF03226.9 KOS23244.1 - 0.13 12.3 0.6 0.5 10.4 0.4 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.7 KOS23244.1 - 0.18 11.1 1.2 0.34 10.2 0.1 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding zf-Mss51 PF13824.1 KOS23244.1 - 1 9.2 6.4 3.9 7.4 0.6 3.2 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-NADH-PPase PF09297.6 KOS23244.1 - 1.1 8.7 6.9 4.8 6.7 0.1 3.4 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain ArfGap PF01412.13 KOS23245.1 - 1.2e-40 137.9 0.8 1.2e-40 137.9 0.5 1.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAF1_ABF1 PF04684.8 KOS23245.1 - 3.5 6.3 12.6 5.3 5.7 8.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor OCD_Mu_crystall PF02423.10 KOS23246.1 - 1.5e-15 56.7 0.1 4.2e-12 45.4 0.0 2.9 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Thiolase_N PF00108.18 KOS23247.1 - 1.3e-75 253.7 0.5 1.8e-75 253.3 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KOS23247.1 - 4.2e-42 142.4 0.1 9.7e-42 141.2 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 KOS23247.1 - 0.00014 21.7 0.0 0.00043 20.2 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal NUDIX PF00293.23 KOS23248.1 - 0.076 12.6 0.0 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 NUDIX domain DUF1977 PF09320.6 KOS23249.1 - 7.8e-21 74.3 0.0 1.4e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KOS23249.1 - 3.5e-20 71.4 0.1 5.7e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S19 PF00203.16 KOS23250.1 - 5.9e-24 83.4 0.0 6.9e-24 83.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.8 KOS23251.1 - 9.2e-25 86.2 0.2 1.4e-24 85.6 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 KOS23251.1 - 0.1 13.0 0.4 0.23 11.9 0.3 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Peptidase_S28 PF05577.7 KOS23253.1 - 2.9e-46 157.9 0.5 5.9e-46 156.9 0.3 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Steroid_dh PF02544.11 KOS23254.1 - 4e-15 55.8 0.0 5.1e-11 42.5 0.0 2.6 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KOS23254.1 - 0.006 15.9 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF544 PF04424.8 KOS23255.1 - 4e-14 52.4 0.0 7e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) R3H PF01424.17 KOS23256.1 - 1.3e-11 44.0 0.1 2.6e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 KOS23256.1 - 6.2e-07 29.3 0.1 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS23256.1 - 1.9e-05 24.3 0.0 3.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS23256.1 - 9e-05 22.0 0.0 0.00026 20.5 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.19 KOS23257.1 - 3.4e-22 78.3 0.0 4.5e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KOS23257.1 - 3.1e-05 23.9 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Myb_DNA-binding PF00249.26 KOS23258.1 - 0.0037 17.2 0.0 0.0088 16.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KOS23258.1 - 0.025 14.6 0.4 0.06 13.4 0.3 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain EF-hand_6 PF13405.1 KOS23258.1 - 0.081 12.8 0.0 0.76 9.8 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain DS PF01916.12 KOS23259.1 - 9.9e-145 481.2 0.0 1.1e-144 481.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 KOS23259.1 - 0.051 12.6 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase Aldo_ket_red PF00248.16 KOS23260.1 - 1.9e-21 76.1 0.0 2.7e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family CO_deh_flav_C PF03450.12 KOS23260.1 - 0.036 14.0 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain GFO_IDH_MocA PF01408.17 KOS23261.1 - 7.6e-18 65.1 0.2 1.2e-17 64.4 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KOS23261.1 - 0.024 15.0 0.1 0.04 14.3 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Skp1_POZ PF03931.10 KOS23262.1 - 2.4e-10 40.3 0.0 3.3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Ras PF00071.17 KOS23263.1 - 1.3e-47 161.2 0.0 1.5e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS23263.1 - 2.6e-11 44.0 0.0 4.1e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS23263.1 - 5.3e-06 25.7 0.0 1.5e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family DASH_Dad1 PF08649.5 KOS23264.1 - 1.9e-23 81.9 0.4 2.3e-23 81.6 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 WVELL PF14043.1 KOS23264.1 - 0.03 13.9 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 WVELL protein PilJ PF13675.1 KOS23264.1 - 0.046 14.0 0.2 0.054 13.8 0.1 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term FliE PF02049.13 KOS23264.1 - 0.18 11.8 1.8 0.25 11.3 0.1 1.8 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE zf-A20 PF01754.11 KOS23265.1 - 0.1 12.1 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 A20-like zinc finger SET PF00856.23 KOS23266.1 - 1.8e-10 41.3 0.0 2.5e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 SET domain DBR1 PF05011.8 KOS23267.1 - 8e-47 158.7 0.0 1.7e-46 157.7 0.0 1.5 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KOS23267.1 - 3.8e-08 32.9 0.3 8.7e-08 31.7 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase GRP PF07172.6 KOS23267.1 - 0.67 10.4 13.4 0.31 11.5 7.0 2.0 2 0 0 2 2 2 0 Glycine rich protein family FA_desaturase PF00487.19 KOS23268.1 - 1.4e-30 106.6 20.5 1.4e-30 106.6 14.2 1.5 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.5 KOS23268.1 - 1.8e-18 65.4 0.1 3.4e-18 64.5 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.21 KOS23269.1 - 9.3e-24 83.1 0.2 3.3e-23 81.4 0.1 1.8 1 1 1 2 2 2 1 MSP (Major sperm protein) domain DUF4094 PF13334.1 KOS23269.1 - 0.013 15.8 1.7 5.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Kelch_5 PF13854.1 KOS23271.1 - 1.4e-09 37.7 6.2 4.4e-09 36.0 0.5 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 KOS23271.1 - 0.0024 17.5 9.6 0.51 10.1 0.1 4.6 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 KOS23271.1 - 0.0029 17.1 0.8 0.076 12.5 0.1 3.3 3 0 0 3 3 3 1 Kelch motif DUF2029 PF09594.5 KOS23271.1 - 0.0086 15.6 0.4 0.018 14.5 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) BIR PF00653.16 KOS23272.1 - 2.1e-40 136.9 4.3 1.3e-20 73.6 0.0 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain AT_hook PF02178.14 KOS23272.1 - 0.00017 20.8 30.3 0.093 12.4 1.1 5.0 4 0 0 4 4 4 3 AT hook motif MFS_1 PF07690.11 KOS23273.1 - 1.7e-30 105.9 28.5 1.7e-30 105.9 19.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.17 KOS23273.1 - 0.81 8.4 31.1 0.15 10.8 9.2 2.7 2 1 0 2 2 2 0 Acyltransferase family GrpE PF01025.14 KOS23274.1 - 5.4e-48 162.6 5.2 9.1e-48 161.9 3.6 1.4 1 1 0 1 1 1 1 GrpE DUF334 PF03904.8 KOS23274.1 - 0.036 13.3 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Bap31 PF05529.7 KOS23274.1 - 1.9 7.8 4.7 1.2 8.6 2.0 1.5 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like MBD_C PF14048.1 KOS23275.1 - 0.025 15.1 0.2 0.099 13.2 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 COG2 PF06148.6 KOS23275.1 - 0.09 12.6 0.2 0.28 11.0 0.2 1.8 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 PAT1 PF09770.4 KOS23276.1 - 3.9 5.6 12.6 5 5.2 8.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAP PF07174.6 KOS23276.1 - 4.1 6.6 25.5 5.8 6.1 17.7 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PCI PF01399.22 KOS23277.1 - 2.9e-21 75.7 1.0 1.1e-20 73.8 0.1 2.4 3 0 0 3 3 3 1 PCI domain DDRGK PF09756.4 KOS23277.1 - 0.00046 19.6 0.2 0.00091 18.6 0.1 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_8 PF13181.1 KOS23277.1 - 0.001 18.6 0.2 8.4 6.4 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS23277.1 - 0.011 15.4 2.8 6.3 6.8 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KOS23277.1 - 0.013 15.3 1.0 24 5.1 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KOS23277.1 - 0.065 12.8 0.1 13 5.5 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KOS23277.1 - 0.19 12.2 2.6 17 6.1 0.1 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KOS23277.1 - 0.91 10.1 4.5 0.94 10.0 0.0 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KOS23277.1 - 1 9.3 17.4 1.2 9.0 0.4 5.1 4 2 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KOS23277.1 - 3.9 8.2 14.2 8.6 7.1 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KOS23277.1 - 5.8 7.8 12.9 15 6.5 0.2 5.7 6 1 1 7 7 7 0 Tetratricopeptide repeat Rep_fac_C PF08542.6 KOS23278.1 - 3.1e-23 81.5 0.1 1e-22 79.9 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KOS23278.1 - 3.3e-12 46.3 0.0 5.8e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KOS23278.1 - 2.5e-06 27.7 0.1 5.8e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS23278.1 - 1.1e-05 25.6 0.7 9.5e-05 22.5 0.2 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KOS23278.1 - 0.0009 19.2 2.7 0.034 14.1 0.9 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KOS23278.1 - 0.0017 18.2 0.1 0.0037 17.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KOS23278.1 - 0.012 15.1 0.5 1.3 8.3 0.0 2.8 2 1 0 3 3 3 0 AAA-like domain SNF2_N PF00176.18 KOS23278.1 - 0.016 14.0 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Arch_ATPase PF01637.13 KOS23278.1 - 0.034 13.8 0.0 0.067 12.8 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase T4SS-DNA_transf PF02534.9 KOS23278.1 - 0.051 12.1 0.0 0.15 10.6 0.0 1.7 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer ABC_tran PF00005.22 KOS23278.1 - 0.053 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.10 KOS23278.1 - 0.077 11.6 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 KOS23278.1 - 0.15 11.5 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KOS23278.1 - 0.15 11.7 0.6 0.67 9.6 0.4 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AMP-binding PF00501.23 KOS23279.1 - 1.7e-91 306.7 0.2 2.1e-91 306.3 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS23279.1 - 7.3e-21 74.8 0.6 9.5e-19 68.1 0.6 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RFC1 PF08519.7 KOS23280.1 - 1.7e-55 187.0 0.0 3.3e-55 186.0 0.0 1.5 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KOS23280.1 - 2.3e-14 53.3 0.0 5e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KOS23280.1 - 4.2e-08 33.4 0.0 1.2e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KOS23280.1 - 3.1e-05 24.7 0.1 0.00016 22.4 0.0 2.4 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.10 KOS23280.1 - 0.00015 20.6 0.0 0.00026 19.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KOS23280.1 - 0.00043 20.4 0.0 0.0035 17.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KOS23280.1 - 0.00048 20.4 0.1 0.0017 18.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS23280.1 - 0.00053 19.6 0.1 0.0014 18.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 KOS23280.1 - 0.0012 18.4 0.0 0.0039 16.7 0.0 1.9 2 0 0 2 2 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 KOS23280.1 - 0.0063 16.5 0.5 0.052 13.5 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 KOS23280.1 - 0.014 15.2 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KOS23280.1 - 0.037 13.6 0.0 1.9 8.1 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 KOS23280.1 - 0.046 13.6 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KOS23280.1 - 0.071 12.8 0.3 0.16 11.6 0.0 1.7 2 0 0 2 2 1 0 NTPase RuvB_N PF05496.7 KOS23280.1 - 0.087 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KOS23280.1 - 0.096 12.6 0.0 0.096 12.6 0.0 2.5 3 0 0 3 3 2 0 AAA domain PTCB-BRCT PF12738.2 KOS23280.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain Acyl-CoA_dh_1 PF00441.19 KOS23280.1 - 0.54 10.3 2.5 1.2 9.2 1.7 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_L16 PF00252.13 KOS23281.1 - 8.3e-28 96.7 1.1 1.1e-27 96.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Fijivirus_P9-2 PF06837.6 KOS23282.1 - 5.3 6.1 22.9 5.8 5.9 15.9 1.1 1 0 0 1 1 1 0 Fijivirus P9-2 protein MMS1_N PF10433.4 KOS23285.1 - 2.7e-73 246.8 0.0 5.2e-73 245.8 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KOS23285.1 - 5.7e-59 199.7 0.0 1.3e-58 198.6 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region Ion_trans PF00520.26 KOS23286.1 - 3.9e-06 26.2 17.9 1.1e-05 24.7 10.7 2.6 2 1 0 2 2 2 1 Ion transport protein PKD_channel PF08016.7 KOS23286.1 - 0.00018 20.1 10.0 0.0076 14.7 0.1 2.2 1 1 1 2 2 2 2 Polycystin cation channel Adeno_E3_CR2 PF02439.10 KOS23287.1 - 0.016 14.7 0.6 0.034 13.6 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ribosomal_60s PF00428.14 KOS23288.1 - 2.6 8.5 18.3 1.6 9.1 0.3 3.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein Peptidase_S9 PF00326.16 KOS23289.1 - 7.1e-43 146.2 0.0 1.2e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KOS23289.1 - 2.2e-08 33.9 0.4 8.5e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.7 KOS23289.1 - 0.00036 19.1 0.0 0.042 12.3 0.0 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.5 KOS23289.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DUF2457 PF10446.4 KOS23289.1 - 0.12 11.0 8.2 0.17 10.5 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Tom22 PF04281.8 KOS23289.1 - 0.85 9.1 3.4 1.4 8.4 2.4 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Nucleoplasmin PF03066.10 KOS23289.1 - 1.7 8.1 9.1 2.8 7.4 6.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin TAP42 PF04177.7 KOS23289.1 - 8.2 5.2 6.4 11 4.7 4.4 1.1 1 0 0 1 1 1 0 TAP42-like family Peptidase_M28 PF04389.12 KOS23290.1 - 5.9e-27 94.5 0.4 1.1e-26 93.7 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KOS23290.1 - 7.4e-05 22.3 0.1 0.00012 21.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 R3H-assoc PF13902.1 KOS23291.1 - 0.0014 18.6 2.0 0.0034 17.3 1.0 2.1 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 KOS23291.1 - 0.0019 17.8 0.0 0.0041 16.7 0.0 1.6 1 0 0 1 1 1 1 R3H domain WD40 PF00400.27 KOS23292.1 - 0.0036 17.1 10.8 0.041 13.7 0.7 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat PQ-loop PF04193.9 KOS23293.1 - 1e-24 85.8 8.1 4.9e-13 48.4 0.8 3.1 2 1 1 3 3 3 2 PQ loop repeat DUF2975 PF11188.3 KOS23293.1 - 0.0082 15.8 2.6 0.0082 15.8 1.8 3.0 2 1 2 4 4 4 1 Protein of unknown function (DUF2975) DUF3796 PF12676.2 KOS23293.1 - 0.022 14.9 0.8 0.022 14.9 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) ER_lumen_recept PF00810.13 KOS23293.1 - 0.07 13.6 2.6 0.093 13.2 0.8 1.9 2 0 0 2 2 2 0 ER lumen protein retaining receptor G_glu_transpept PF01019.16 KOS23294.1 - 2.3e-143 478.4 0.0 2.6e-143 478.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Amidohydro_3 PF07969.6 KOS23295.1 - 7e-57 193.4 3.5 8.2e-57 193.2 2.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KOS23295.1 - 6.4e-10 38.7 0.1 2.1e-09 37.0 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KOS23295.1 - 5.2e-06 26.6 7.3 7e-06 26.2 0.0 3.0 1 1 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 KOS23295.1 - 7.1e-06 25.9 0.1 0.00086 19.0 0.1 3.0 2 1 0 2 2 2 1 Amidohydrolase family BPL_LplA_LipB PF03099.14 KOS23297.1 - 3e-13 49.8 0.0 6.3e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 KOS23298.1 - 1e-128 428.6 0.0 1.3e-128 428.3 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase Hormone_4 PF00220.12 KOS23298.1 - 0.34 10.6 7.8 2.3 8.0 2.3 2.6 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain BC10 PF06726.7 KOS23300.1 - 8.1e-18 64.2 10.9 1.8e-17 63.0 7.6 1.6 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF445 PF04286.7 KOS23301.1 - 3.7e-05 23.4 2.1 7.4e-05 22.4 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF1640 PF07798.6 KOS23301.1 - 5.2 7.0 12.2 0.6 10.1 1.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Pro_isomerase PF00160.16 KOS23302.1 - 5e-45 153.4 0.2 7.9e-45 152.8 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KOS23302.1 - 4.6e-13 48.6 3.2 4.1e-08 32.7 0.1 2.6 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KOS23302.1 - 1.5e-06 27.6 2.2 0.00047 19.8 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KOS23302.1 - 1.2e-05 24.6 1.3 0.00051 19.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KOS23302.1 - 0.0015 18.4 0.7 0.63 10.0 0.3 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KOS23302.1 - 0.39 10.6 3.9 1.1 9.2 2.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_10 PF12846.2 KOS23303.1 - 2.6e-07 30.3 0.0 0.0071 15.8 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.12 KOS23303.1 - 0.0021 17.9 0.0 0.37 10.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 KOS23303.1 - 0.0074 16.4 0.1 1.7 8.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 KOS23303.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KOS23303.1 - 0.025 13.6 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 KOS23303.1 - 0.049 13.6 1.1 0.2 11.6 0.1 2.3 2 1 1 3 3 3 0 AAA ATPase domain Zot PF05707.7 KOS23303.1 - 0.18 11.2 0.1 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Nucleoplasmin PF03066.10 KOS23303.1 - 0.22 11.0 9.6 0.54 9.7 6.6 1.6 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 KOS23303.1 - 0.23 11.6 5.1 0.063 13.4 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF4604 PF15377.1 KOS23303.1 - 0.24 11.6 8.1 0.92 9.7 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) RXT2_N PF08595.6 KOS23303.1 - 0.81 9.4 4.3 1.6 8.4 3.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 KOS23303.1 - 0.92 9.0 5.9 1.8 8.1 4.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 KOS23303.1 - 1.2 9.4 13.4 2.9 8.2 9.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.8 KOS23303.1 - 4.4 6.8 6.4 11 5.5 4.4 1.6 1 0 0 1 1 1 0 YL1 nuclear protein GST_N_3 PF13417.1 KOS23304.1 - 5.5e-23 80.9 0.0 1.9e-22 79.2 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KOS23304.1 - 4.3e-16 58.6 0.0 8.5e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KOS23304.1 - 2.2e-05 24.5 0.0 0.011 15.9 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KOS23304.1 - 2.3e-05 24.1 1.0 6e-05 22.8 0.7 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KOS23304.1 - 0.0015 18.9 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KOS23304.1 - 0.0085 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain XAP5 PF04921.9 KOS23305.1 - 4.4e-80 268.7 0.1 1.4e-79 267.0 0.0 1.8 1 1 1 2 2 2 1 XAP5, circadian clock regulator FLO_LFY PF01698.11 KOS23305.1 - 0.0037 16.1 10.3 0.0037 16.1 7.2 1.8 1 1 1 2 2 2 1 Floricaula / Leafy protein DUF4604 PF15377.1 KOS23305.1 - 0.013 15.7 13.5 0.013 15.7 9.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4604) MSP1_C PF07462.6 KOS23305.1 - 0.16 10.3 2.9 0.25 9.7 2.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus API5 PF05918.6 KOS23305.1 - 1.2 7.5 7.3 1.7 7.0 5.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Striatin PF08232.7 KOS23305.1 - 8.7 6.6 12.3 0.53 10.5 2.0 2.4 2 0 0 2 2 2 0 Striatin family adh_short_C2 PF13561.1 KOS23307.1 - 1.4e-24 87.1 0.0 1.7e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KOS23307.1 - 3.1e-22 79.2 6.7 4.5e-22 78.7 4.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS23307.1 - 2.5e-11 43.5 4.1 3.8e-11 42.9 2.8 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KOS23307.1 - 5.7e-06 25.9 0.0 2e-05 24.1 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KOS23307.1 - 0.0088 14.7 0.1 0.011 14.4 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KOS23307.1 - 0.01 14.7 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF218 PF02698.12 KOS23308.1 - 1.1e-32 112.7 0.1 1.3e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain Methyltransf_10 PF05971.7 KOS23309.1 - 7.4e-66 222.3 0.0 1.1e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 KOS23309.1 - 1.2e-05 24.7 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KOS23309.1 - 5.2e-05 23.7 0.0 0.00013 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS23309.1 - 0.00026 20.9 0.0 0.0006 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KOS23309.1 - 0.00034 19.8 0.0 0.00058 19.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 KOS23309.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 KOS23309.1 - 0.14 12.6 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF4231 PF14015.1 KOS23310.1 - 0.0087 16.0 0.1 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) Fungal_trans PF04082.13 KOS23312.1 - 6.4e-12 44.9 0.2 1e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS23312.1 - 6.6e-06 25.9 7.2 1.3e-05 24.9 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain But2 PF09792.4 KOS23313.1 - 3.4e-40 137.0 0.0 9.6e-40 135.6 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3744 PF12558.3 KOS23314.1 - 0.042 14.3 0.5 0.049 14.0 0.4 1.2 1 0 0 1 1 1 0 ATP-binding cassette cobalt transporter adh_short PF00106.20 KOS23316.1 - 3.5e-26 92.0 0.1 5.2e-26 91.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS23316.1 - 6.2e-22 78.5 0.0 1.5e-21 77.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS23316.1 - 7.3e-12 45.3 0.1 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KOS23316.1 - 0.00022 20.7 0.1 0.00062 19.2 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HHH_5 PF14520.1 KOS23316.1 - 0.0066 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain Ldh_1_N PF00056.18 KOS23316.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.16 KOS23316.1 - 0.052 13.3 0.2 0.2 11.4 0.1 1.9 1 1 1 2 2 2 0 ThiF family Spc7_N PF15402.1 KOS23317.1 - 0.79 7.6 9.3 0.9 7.4 6.4 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Spt5-NGN PF03439.8 KOS23318.1 - 3.8e-22 77.8 0.0 6.5e-22 77.0 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.2 KOS23318.1 - 6.7e-21 74.9 42.0 1.5e-13 51.2 18.4 3.6 1 1 2 3 3 3 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 KOS23318.1 - 1.9e-19 70.0 12.1 1.9e-19 70.0 8.4 5.3 2 1 2 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 KOS23318.1 - 3.2e-05 23.4 14.8 0.0059 16.2 0.8 4.9 6 0 0 6 6 6 2 KOW motif adh_short PF00106.20 KOS23321.1 - 2.2e-25 89.5 0.1 3.1e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS23321.1 - 2.6e-23 83.0 0.0 3.3e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS23321.1 - 1.4e-13 50.9 0.0 2.5e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KOS23321.1 - 0.029 13.0 0.0 0.039 12.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SAGA-Tad1 PF12767.2 KOS23321.1 - 0.039 13.6 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit NAD_binding_7 PF13241.1 KOS23321.1 - 0.07 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Methyltransf_11 PF08241.7 KOS23321.1 - 0.073 13.5 0.0 5 7.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain YjeF_N PF03853.10 KOS23321.1 - 0.1 12.1 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus ELFV_dehydrog PF00208.16 KOS23321.1 - 0.11 12.0 0.1 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pyr_redox PF00070.22 KOS23321.1 - 0.14 12.5 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aa_trans PF01490.13 KOS23322.1 - 3.5e-72 243.1 23.6 4.5e-72 242.7 16.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Polysacc_synt_4 PF04669.8 KOS23323.1 - 1.4e-26 93.0 1.7 8.3e-26 90.5 1.2 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis Abhydrolase_6 PF12697.2 KOS23325.1 - 3e-13 50.1 2.3 4.2e-13 49.6 0.3 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS23325.1 - 0.00019 21.0 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS23325.1 - 0.00073 19.3 0.3 0.0018 18.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KOS23325.1 - 0.0098 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Cupin_2 PF07883.6 KOS23326.1 - 8.4e-14 50.8 0.1 1.4e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KOS23326.1 - 1.6e-05 24.3 0.0 2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KOS23326.1 - 5.1e-05 22.5 0.0 8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 KOS23326.1 - 0.00018 21.1 0.4 0.00033 20.3 0.3 1.6 1 1 0 1 1 1 1 Cupin AraC_binding PF02311.14 KOS23326.1 - 0.0057 16.3 0.1 0.0091 15.6 0.1 1.4 1 1 0 1 1 1 1 AraC-like ligand binding domain MFS_1 PF07690.11 KOS23327.1 - 7.7e-29 100.4 21.6 7.7e-29 100.4 15.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS23327.1 - 1.8e-08 33.4 8.2 1.8e-08 33.4 5.7 2.6 3 1 0 3 3 3 2 Sugar (and other) transporter DUF1769 PF08588.5 KOS23328.1 - 8.6e-30 102.4 0.2 2.2e-29 101.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) mRNA_triPase PF02940.10 KOS23329.1 - 1.8e-48 165.1 0.1 2.6e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Xan_ur_permease PF00860.15 KOS23330.1 - 3.2e-64 216.8 24.6 2.9e-62 210.3 17.1 2.1 1 1 0 1 1 1 1 Permease family Oxidored_molyb PF00174.14 KOS23331.1 - 8.7e-55 184.7 0.0 1.3e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KOS23331.1 - 9.6e-24 83.4 0.2 8.5e-13 48.0 0.0 3.1 3 0 0 3 3 3 2 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 KOS23331.1 - 5.8e-14 51.6 0.2 1.1e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.15 KOS23331.1 - 0.11 12.3 0.8 0.57 10.2 0.1 2.5 2 0 0 2 2 2 0 BNR/Asp-box repeat PC_rep PF01851.17 KOS23332.1 - 3e-41 137.3 18.1 5.2e-08 32.6 0.0 9.9 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KOS23332.1 - 1.6e-18 66.7 0.8 2.8e-12 46.7 0.0 5.3 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.17 KOS23332.1 - 9.2e-08 31.5 4.3 0.79 9.9 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 KOS23332.1 - 1.2e-06 28.7 5.0 0.00016 22.0 0.0 5.2 5 2 1 6 6 6 1 HEAT-like repeat Abhydrolase_5 PF12695.2 KOS23333.1 - 7.3e-08 32.2 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS23333.1 - 3e-07 30.5 0.4 5.6e-07 29.6 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KOS23333.1 - 0.00034 20.2 0.0 0.00071 19.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3446 PF11928.3 KOS23333.1 - 0.0075 16.4 10.2 0.015 15.4 7.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3446) DUF1517 PF07466.6 KOS23333.1 - 0.88 8.4 7.5 1.3 7.9 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) BTB PF00651.26 KOS23334.1 - 2.3e-07 30.7 0.1 1.1e-06 28.5 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain Skp1_POZ PF03931.10 KOS23334.1 - 0.13 12.3 0.0 0.56 10.3 0.0 2.0 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain PCI PF01399.22 KOS23335.1 - 1.4e-08 34.9 0.0 8.8e-08 32.4 0.0 2.4 2 1 0 2 2 2 1 PCI domain Ribosomal_L18ae PF01775.12 KOS23336.1 - 5.3e-57 191.0 0.3 6.5e-57 190.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Acetyltransf_3 PF13302.1 KOS23337.1 - 1.8e-32 112.4 0.0 2.4e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS23337.1 - 0.00016 21.6 0.1 0.00046 20.1 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KOS23337.1 - 0.017 14.9 0.0 0.26 11.1 0.0 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Ric8 PF10165.4 KOS23338.1 - 6e-100 335.1 0.0 7.4e-100 334.8 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.3 KOS23339.1 - 3.7e-114 381.5 0.0 5.4e-114 381.0 0.0 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Imm29 PF15575.1 KOS23339.1 - 0.018 14.6 0.1 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 29 DUF3508 PF12018.3 KOS23339.1 - 0.18 10.7 0.0 0.44 9.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) Sugar_tr PF00083.19 KOS23340.1 - 8.9e-103 344.2 22.9 1.1e-102 344.0 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS23340.1 - 1.4e-22 79.9 34.2 2.1e-14 53.0 5.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KOS23340.1 - 9.6e-06 23.9 0.4 2e-05 22.8 0.3 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF697 PF05128.7 KOS23340.1 - 0.096 12.1 1.1 2.6 7.5 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF697) Aldo_ket_red PF00248.16 KOS23341.1 - 1.3e-49 168.5 0.0 1.5e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF777 PF05606.6 KOS23341.1 - 0.067 12.3 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) LRR_4 PF12799.2 KOS23342.1 - 3.1e-42 141.5 22.9 1.7e-10 40.3 0.2 7.3 3 2 5 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS23342.1 - 3.3e-22 77.9 14.4 4.3e-08 32.7 0.2 4.6 2 1 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 KOS23342.1 - 1.3e-13 48.8 17.8 0.65 10.2 0.1 10.0 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.1 KOS23342.1 - 3.4e-13 48.1 13.3 0.19 11.8 0.2 9.5 9 1 2 11 11 11 4 Leucine Rich repeat LRR_7 PF13504.1 KOS23342.1 - 3.5e-13 47.4 10.7 0.45 10.9 0.1 8.7 9 0 0 9 9 9 3 Leucine rich repeat LRR_9 PF14580.1 KOS23342.1 - 8.4e-13 48.2 21.0 1.8e-05 24.4 1.2 3.2 1 1 4 5 5 5 5 Leucine-rich repeat DKNYY PF13644.1 KOS23342.1 - 0.035 14.3 0.2 1.4 9.1 0.1 2.4 2 1 0 2 2 2 0 DKNYY family IMS PF00817.15 KOS23343.1 - 1.5e-44 151.4 1.3 2.2e-44 150.8 0.2 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KOS23343.1 - 4.3e-15 55.7 0.0 1.1e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KOS23343.1 - 0.00031 20.6 0.0 0.00078 19.3 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif DUF2071 PF09844.4 KOS23344.1 - 0.074 12.4 0.4 0.15 11.4 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) DUF3284 PF11687.3 KOS23344.1 - 0.22 11.2 1.7 16 5.2 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3284) Cornichon PF03311.9 KOS23345.1 - 4.9e-54 181.8 11.4 5.6e-54 181.7 7.9 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1673 PF07895.6 KOS23345.1 - 4.4 6.7 7.9 4.9 6.6 4.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) CTP_transf_2 PF01467.21 KOS23346.1 - 0.00058 19.9 0.2 0.029 14.4 0.5 2.3 2 0 0 2 2 2 2 Cytidylyltransferase SET PF00856.23 KOS23347.1 - 7.6e-09 36.0 0.0 1e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 SET domain WD40 PF00400.27 KOS23348.1 - 2.9e-36 122.0 3.8 1.7e-07 30.8 0.0 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 KOS23348.1 - 0.0039 15.4 0.1 0.37 8.8 0.0 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KOS23348.1 - 0.0045 16.7 1.2 0.27 10.9 0.2 2.7 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Barttin PF15462.1 KOS23348.1 - 0.032 13.8 0.3 0.032 13.8 0.2 1.6 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Methyltransf_24 PF13578.1 KOS23349.1 - 1.7e-09 38.4 0.0 3.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS23349.1 - 3.9e-05 24.2 0.0 6.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 KOS23349.1 - 0.022 14.0 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase adh_short PF00106.20 KOS23349.1 - 0.066 13.1 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.13 KOS23349.1 - 0.17 11.8 0.0 0.6 10.1 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain CR6_interact PF10147.4 KOS23351.1 - 0.0045 16.3 1.4 0.0088 15.3 1.0 1.5 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 EphA2_TM PF14575.1 KOS23351.1 - 0.016 15.6 0.1 0.051 13.9 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1675 PF07897.6 KOS23351.1 - 0.13 12.0 11.2 0.034 14.0 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1675) DUF1049 PF06305.6 KOS23351.1 - 0.15 11.5 0.0 0.46 9.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Flavodoxin_1 PF00258.20 KOS23352.1 - 4.2e-09 36.5 0.0 6.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 KOS23352.1 - 3.5e-07 29.9 0.0 4.3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 KOS23352.1 - 9e-07 28.5 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.2 KOS23352.1 - 0.13 12.2 0.0 1 9.3 0.0 2.0 1 1 1 2 2 2 0 Flavodoxin domain TPT PF03151.11 KOS23353.1 - 1.1e-24 86.8 9.8 1.1e-24 86.8 6.8 2.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KOS23353.1 - 1.3e-05 24.2 18.7 2.3e-05 23.4 13.0 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KOS23353.1 - 0.14 12.2 30.8 0.5 10.4 9.2 2.7 2 1 0 2 2 2 0 EamA-like transporter family RasGAP_C PF03836.10 KOS23354.1 - 1.1e-48 164.5 6.2 3.8e-48 162.7 4.3 2.0 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 KOS23354.1 - 3.3e-42 144.3 0.0 8.4e-42 143.0 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 KOS23354.1 - 3.3e-18 63.5 48.3 0.0059 16.1 0.1 15.1 16 0 0 16 16 16 7 IQ calmodulin-binding motif CH PF00307.26 KOS23354.1 - 1.6e-10 40.9 0.0 6e-10 39.1 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain TNFR_c6 PF00020.13 KOS23355.1 - 8.7 6.4 8.4 0.41 10.7 0.4 2.7 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region DUF155 PF02582.9 KOS23356.1 - 2.3e-59 200.2 0.1 4e-59 199.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 LBP_BPI_CETP_C PF02886.12 KOS23356.1 - 0.17 11.0 0.1 0.31 10.2 0.1 1.3 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain SGL PF08450.7 KOS23358.1 - 2.3e-23 82.8 0.0 3.7e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 KOS23358.1 - 6.1e-06 26.1 0.0 3.1e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 KOS23358.1 - 0.0036 17.2 0.0 0.013 15.4 0.0 2.0 1 1 0 1 1 1 1 Arylesterase RabGAP-TBC PF00566.13 KOS23359.1 - 9.3e-35 120.0 0.0 1.3e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2638 PF10937.3 KOS23359.1 - 0.023 15.7 0.4 0.17 12.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) PalH PF08733.5 KOS23360.1 - 0.18 10.6 1.5 0.27 10.0 1.1 1.2 1 0 0 1 1 1 0 PalH/RIM21 EI24 PF07264.6 KOS23360.1 - 0.39 10.0 22.0 4.6 6.6 15.2 2.1 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) COG5 PF10392.4 KOS23361.1 - 2e-40 137.8 1.8 3.6e-39 133.7 0.1 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Actino_peptide PF14408.1 KOS23361.1 - 0.011 15.6 6.3 0.029 14.2 4.3 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes CENP-F_leu_zip PF10473.4 KOS23361.1 - 0.057 13.2 0.3 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PhoU_div PF01865.11 KOS23361.1 - 0.087 11.9 0.2 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF47 SPX PF03105.14 KOS23361.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 SPX domain HTH_32 PF13565.1 KOS23361.1 - 0.71 10.7 3.0 0.72 10.6 0.1 2.5 3 1 0 3 3 3 0 Homeodomain-like domain DUF2434 PF10361.4 KOS23362.1 - 3.3e-110 367.8 6.2 4.2e-110 367.4 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) Bacteriocin_II PF01721.13 KOS23362.1 - 0.046 13.2 1.7 0.13 11.8 1.1 1.8 1 0 0 1 1 1 0 Class II bacteriocin Zn_clus PF00172.13 KOS23364.1 - 1.8e-08 34.1 9.9 2.8e-08 33.5 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KOS23364.1 - 0.00059 18.7 0.7 0.0016 17.3 0.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain PAT1 PF09770.4 KOS23364.1 - 0.067 11.4 21.3 0.092 10.9 14.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AUX_IAA PF02309.11 KOS23364.1 - 0.3 10.8 4.3 0.47 10.1 3.0 1.3 1 0 0 1 1 1 0 AUX/IAA family Ycf1 PF05758.7 KOS23364.1 - 0.41 8.3 2.2 0.54 7.9 1.6 1.1 1 0 0 1 1 1 0 Ycf1 MCPVI PF02993.9 KOS23364.1 - 0.7 10.0 10.0 1.3 9.1 6.9 1.4 1 0 0 1 1 1 0 Minor capsid protein VI FLO_LFY PF01698.11 KOS23364.1 - 0.8 8.4 5.7 1.2 7.8 3.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Glyco_transf_20 PF00982.16 KOS23365.1 - 2.9e-150 500.8 0.0 3.9e-150 500.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KOS23365.1 - 7.2e-75 250.9 0.0 1.4e-74 249.9 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_trans_1_4 PF13692.1 KOS23365.1 - 0.011 15.8 0.0 0.31 11.2 0.0 2.7 2 1 0 2 2 2 0 Glycosyl transferases group 1 TraW_N PF12477.3 KOS23366.1 - 0.099 12.6 1.4 0.16 11.9 1.0 1.3 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal Sugar_tr PF00083.19 KOS23367.1 - 1.5e-128 429.2 25.2 1.7e-128 429.0 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS23367.1 - 1.2e-21 76.8 43.2 1e-14 54.0 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KOS23367.1 - 0.22 11.3 0.1 0.22 11.3 0.0 4.2 3 1 1 4 4 4 0 MFS_1 like family DUF1228 PF06779.9 KOS23367.1 - 1.3 9.1 7.3 0.48 10.4 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Aconitase PF00330.15 KOS23368.1 - 1.3e-174 581.0 0.0 3.2e-174 579.7 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KOS23368.1 - 4.1e-44 149.8 0.0 7.3e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.3 KOS23369.1 - 4.8e-09 36.0 0.0 7.8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS23369.1 - 0.012 15.7 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KOS23369.1 - 0.074 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Tropomyosin_1 PF12718.2 KOS23369.1 - 0.13 12.1 0.8 0.76 9.6 0.1 1.9 2 0 0 2 2 2 0 Tropomyosin like Gaa1 PF04114.9 KOS23370.1 - 6.8e-97 325.2 0.3 8.8e-97 324.8 0.2 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.17 KOS23371.1 - 3.1e-13 49.9 11.6 4.5e-13 49.4 8.0 1.2 1 0 0 1 1 1 1 Rhomboid family HIT PF01230.18 KOS23372.1 - 4.1e-22 78.5 0.2 5.1e-22 78.2 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KOS23372.1 - 6.9e-15 55.2 0.1 9.4e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KOS23372.1 - 5e-06 26.1 0.0 7.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.1 KOS23372.1 - 0.04 13.9 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Mog1 PF04603.7 KOS23373.1 - 3.9e-11 43.0 0.0 5.2e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein DASH_Dam1 PF08653.5 KOS23374.1 - 3e-27 94.1 1.4 3.9e-27 93.7 0.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Dam1 cIII PF08134.6 KOS23374.1 - 0.21 11.2 1.5 23 4.6 0.0 2.4 2 0 0 2 2 2 0 cIII protein family CRAL_TRIO PF00650.15 KOS23375.1 - 1.7e-44 151.1 0.0 5.1e-44 149.5 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KOS23375.1 - 2.2e-15 56.5 0.3 3.9e-14 52.5 0.1 2.6 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KOS23375.1 - 8.8e-11 41.9 0.0 2.3e-10 40.5 0.0 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Flg_hook PF02120.11 KOS23375.1 - 0.023 14.3 0.5 2.2 8.0 0.0 3.2 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK YopR_core PF09025.5 KOS23375.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 YopR Core SprT-like PF10263.4 KOS23376.1 - 1.4e-54 183.9 1.9 2.1e-54 183.4 1.3 1.2 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.14 KOS23376.1 - 2.3e-05 24.5 2.5 2.6e-05 24.3 0.5 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box Zn-ribbon_8 PF09723.5 KOS23376.1 - 0.011 15.6 1.4 0.024 14.5 1.0 1.6 1 0 0 1 1 1 0 Zinc ribbon domain YABBY PF04690.8 KOS23376.1 - 0.017 15.3 0.3 0.086 13.0 0.0 2.0 1 1 1 2 2 2 0 YABBY protein HMG_box_2 PF09011.5 KOS23376.1 - 0.059 13.7 0.2 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 HMG-box domain DnaJ_CXXCXGXG PF00684.14 KOS23376.1 - 0.084 12.9 1.1 0.18 11.9 0.8 1.5 1 0 0 1 1 1 0 DnaJ central domain Peptidase_MA_2 PF13485.1 KOS23376.1 - 0.11 12.5 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Glucan_synthase PF02364.10 KOS23377.1 - 0 1449.9 0.0 0 1449.4 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KOS23377.1 - 3e-38 130.3 0.5 8.9e-38 128.8 0.4 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.16 KOS23378.1 - 7.4e-37 127.1 0.0 8.8e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Coatomer_WDAD PF04053.9 KOS23379.1 - 1.2e-148 495.5 0.0 2.2e-148 494.7 0.0 1.4 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 KOS23379.1 - 2e-79 267.1 0.0 2.8e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KOS23379.1 - 9.2e-51 168.0 9.1 2.4e-09 36.7 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KOS23379.1 - 0.0077 14.4 5.5 0.37 8.8 0.0 3.8 2 1 2 4 4 4 2 Nucleoporin Nup120/160 UDP-g_GGTase PF06427.6 KOS23380.1 - 9.4e-61 204.7 0.0 2.2e-60 203.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KOS23380.1 - 4.9e-05 22.7 0.2 0.00013 21.4 0.2 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Haem_oxygenas_2 PF14518.1 KOS23380.1 - 0.066 13.3 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 Iron-containing redox enzyme FUSC_2 PF13515.1 KOS23381.1 - 9.5e-24 83.7 7.3 9.5e-24 83.7 5.0 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 KOS23381.1 - 1.1e-11 43.8 4.1 6.4e-11 41.4 0.0 2.7 3 0 0 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.3 KOS23381.1 - 0.00034 19.3 10.9 0.00072 18.3 5.1 3.1 3 2 0 3 3 3 1 Aluminium activated malate transporter FUSC-like PF12805.2 KOS23381.1 - 0.0039 16.1 6.8 0.18 10.6 1.1 2.5 2 0 0 2 2 2 2 FUSC-like inner membrane protein yccS DUF1469 PF07332.6 KOS23381.1 - 0.0094 15.6 6.7 0.0094 15.6 4.6 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF1469) DUF2421 PF10334.4 KOS23381.1 - 0.098 12.2 0.2 1.7 8.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2421) DNA_pol_E_B PF04042.11 KOS23382.1 - 1.6e-62 210.4 0.0 2.3e-62 209.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B XhoI PF04555.8 KOS23382.1 - 0.23 10.8 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease XhoI Fibrillarin_2 PF10113.4 KOS23382.1 - 0.29 9.4 0.0 0.44 8.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein Pkinase PF00069.20 KOS23383.1 - 1.6e-47 161.8 0.1 3.5e-47 160.7 0.0 1.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS23383.1 - 1.1e-31 109.8 0.1 1.9e-31 109.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS23383.1 - 3e-06 26.4 0.0 4.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KOS23383.1 - 0.034 12.9 0.3 0.054 12.3 0.1 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 KOS23383.1 - 0.078 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 KOS23383.1 - 0.12 11.7 0.1 0.29 10.4 0.1 1.7 1 1 0 1 1 1 0 RIO1 family HAD_2 PF13419.1 KOS23384.1 - 1.7e-13 51.1 0.0 2e-11 44.4 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS23384.1 - 1.6e-08 35.2 0.0 0.00019 21.9 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KOS23384.1 - 7.9e-08 31.9 0.5 1.7e-07 30.8 0.2 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 KOS23384.1 - 1e-05 25.8 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2254 PF10011.4 KOS23384.1 - 0.1 11.0 0.1 4.1 5.7 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) PGP_phosphatase PF09419.5 KOS23384.1 - 0.11 11.7 0.0 2 7.7 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase zf-HIT PF04438.11 KOS23385.1 - 5.5e-10 38.7 7.6 8.1e-10 38.1 5.3 1.3 1 0 0 1 1 1 1 HIT zinc finger SSP160 PF06933.6 KOS23385.1 - 3.3 5.5 4.5 4.6 5.0 3.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 EF-hand_4 PF12763.2 KOS23386.1 - 3.1e-37 126.4 0.0 2.7e-16 59.1 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KOS23386.1 - 1.5e-09 37.8 0.0 0.00013 22.0 0.0 3.8 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.27 KOS23386.1 - 3.8e-08 32.0 0.0 0.21 10.9 0.1 5.0 5 0 0 5 5 4 2 EF hand EF-hand_6 PF13405.1 KOS23386.1 - 5.7e-07 28.8 0.3 0.023 14.5 0.0 5.1 5 0 0 5 5 5 1 EF-hand domain UBA PF00627.26 KOS23386.1 - 3.8e-06 26.5 0.0 9.2e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain ATG16 PF08614.6 KOS23386.1 - 0.0046 16.8 18.7 0.0046 16.8 12.9 2.7 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) EF-hand_8 PF13833.1 KOS23386.1 - 0.0058 16.2 0.0 0.41 10.2 0.0 2.7 2 1 0 2 2 2 1 EF-hand domain pair CENP-F_leu_zip PF10473.4 KOS23386.1 - 0.043 13.6 26.2 0.03 14.1 5.9 2.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 KOS23386.1 - 0.043 12.2 21.5 0.064 11.7 14.9 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light CCDC144C PF14915.1 KOS23386.1 - 0.053 12.4 27.0 0.082 11.8 18.7 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region TPR_MLP1_2 PF07926.7 KOS23386.1 - 0.091 12.5 27.2 1.6 8.4 5.1 2.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 KOS23386.1 - 0.095 10.4 26.7 0.16 9.6 18.5 1.3 1 0 0 1 1 1 0 Myosin tail DUF812 PF05667.6 KOS23386.1 - 0.28 9.6 25.0 0.34 9.3 8.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) AAA_13 PF13166.1 KOS23386.1 - 0.29 9.5 20.8 0.54 8.6 14.4 1.3 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 KOS23386.1 - 0.3 9.7 25.8 0.61 8.6 8.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Rab5-bind PF09311.6 KOS23386.1 - 0.33 10.8 31.1 0.014 15.2 6.4 2.2 1 1 1 2 2 2 0 Rabaptin-like protein Reo_sigmaC PF04582.7 KOS23386.1 - 0.58 9.2 12.6 0.068 12.3 2.3 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein APG6 PF04111.7 KOS23386.1 - 0.66 8.9 28.2 1.3 7.9 4.7 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 KOS23386.1 - 0.68 9.4 34.2 7.2 6.1 9.4 2.4 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 KOS23386.1 - 2.6 7.1 28.2 1.6 7.8 3.9 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tup_N PF08581.5 KOS23386.1 - 2.7 8.2 14.6 0.14 12.3 5.0 2.3 2 0 0 2 2 2 0 Tup N-terminal Filament PF00038.16 KOS23386.1 - 3.6 6.9 27.5 12 5.2 8.2 2.5 1 1 0 2 2 2 0 Intermediate filament protein DUF3450 PF11932.3 KOS23386.1 - 6.1 6.0 27.6 0.53 9.5 4.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4200 PF13863.1 KOS23386.1 - 6.3 6.7 24.0 2.4 8.1 3.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF724 PF05266.9 KOS23386.1 - 6.4 6.3 20.0 0.31 10.6 5.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Syntaxin_2 PF14523.1 KOS23386.1 - 6.5 6.8 25.1 30 4.7 11.1 3.2 1 1 1 2 2 2 0 Syntaxin-like protein ADIP PF11559.3 KOS23386.1 - 7 6.5 35.3 17 5.2 5.0 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Syntaxin PF00804.20 KOS23386.1 - 8 6.6 26.5 1.3 9.2 3.5 2.6 1 1 1 2 2 2 0 Syntaxin Sec6 PF06046.8 KOS23387.1 - 6.7e-157 522.9 6.5 1.1e-156 522.2 4.5 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 FAD_binding_2 PF00890.19 KOS23387.1 - 0.00042 19.2 0.1 0.0014 17.5 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain MutS_III PF05192.13 KOS23387.1 - 0.008 15.9 2.8 0.56 9.9 1.9 3.5 1 1 0 1 1 1 1 MutS domain III OmdA PF13376.1 KOS23387.1 - 0.021 14.4 0.0 0.088 12.4 0.0 2.1 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Vps53_N PF04100.7 KOS23387.1 - 0.038 12.7 7.1 0.039 12.7 2.6 2.6 2 1 0 2 2 2 0 Vps53-like, N-terminal DUF755 PF05501.6 KOS23387.1 - 0.21 11.6 0.9 0.4 10.7 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Sec20 PF03908.8 KOS23387.1 - 0.69 9.6 3.9 1.3 8.7 0.6 3.0 3 1 1 4 4 4 0 Sec20 Syntaxin_2 PF14523.1 KOS23387.1 - 0.87 9.6 8.6 2.4 8.2 0.9 3.0 3 0 0 3 3 3 0 Syntaxin-like protein DUF896 PF05979.7 KOS23387.1 - 1 8.9 3.7 2.4 7.8 0.0 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF896) ZZ PF00569.12 KOS23389.1 - 5.8e-08 32.1 16.2 0.00028 20.3 3.8 2.7 3 0 0 3 3 3 2 Zinc finger, ZZ type WD40 PF00400.27 KOS23390.1 - 7.2e-23 79.5 9.4 1.9e-10 40.2 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ADH_zinc_N PF00107.21 KOS23391.1 - 1.8e-32 111.6 0.1 3.1e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KOS23391.1 - 5e-11 43.6 0.0 9.7e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KOS23391.1 - 7.3e-08 32.1 0.0 4.7e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ABC_membrane PF00664.18 KOS23392.1 - 5.3e-35 121.1 12.7 6.9e-35 120.7 8.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region BatA PF07584.6 KOS23392.1 - 0.069 13.3 3.0 5.1 7.3 0.2 2.6 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal DUF3325 PF11804.3 KOS23392.1 - 8.5 6.3 21.9 0.054 13.4 2.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) ABC_tran PF00005.22 KOS23393.1 - 1.7e-29 102.8 0.0 2.6e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KOS23393.1 - 3e-29 102.2 1.3 3.9e-29 101.9 0.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KOS23393.1 - 2.1e-07 31.2 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KOS23393.1 - 2.6e-06 26.8 0.1 0.0068 15.6 0.0 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KOS23393.1 - 0.00041 19.8 0.0 0.00081 18.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KOS23393.1 - 0.00058 19.0 0.0 0.00099 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KOS23393.1 - 0.00061 19.2 0.8 0.0028 17.0 0.3 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KOS23393.1 - 0.0018 18.2 0.0 0.0042 17.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.4 KOS23393.1 - 0.0066 15.0 0.1 0.097 11.2 0.1 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class ABC_membrane_3 PF13748.1 KOS23393.1 - 0.012 14.6 0.2 0.02 13.9 0.2 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region AAA_22 PF13401.1 KOS23393.1 - 0.012 15.7 0.1 0.11 12.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KOS23393.1 - 0.018 15.8 0.0 0.037 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KOS23393.1 - 0.018 14.4 0.0 0.041 13.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_15 PF13175.1 KOS23393.1 - 0.041 12.9 0.0 0.83 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 KOS23393.1 - 0.063 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 KOS23393.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain E1-E2_ATPase PF00122.15 KOS23394.1 - 6.9e-52 175.7 3.7 1.4e-51 174.7 2.6 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KOS23394.1 - 5.6e-41 140.0 2.3 5.6e-41 140.0 1.6 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KOS23394.1 - 3.5e-23 83.1 0.0 4.5e-22 79.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS23394.1 - 3.3e-17 62.2 0.0 7.2e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KOS23394.1 - 2.4e-11 44.1 0.0 5.9e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KOS23394.1 - 2.7e-08 33.1 0.4 9.9e-08 31.3 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KOS23394.1 - 1.4e-05 24.7 0.3 0.00066 19.3 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Dak1_2 PF13684.1 KOS23394.1 - 0.007 15.3 0.4 0.012 14.5 0.2 1.3 1 0 0 1 1 1 1 Dihydroxyacetone kinase family NUP PF06516.6 KOS23395.1 - 3.5e-110 367.7 0.0 4e-110 367.5 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) DHHA1 PF02272.14 KOS23395.1 - 0.095 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 DHHA1 domain Pkinase PF00069.20 KOS23396.1 - 3.3e-45 154.2 0.0 1.2e-44 152.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS23396.1 - 3.4e-31 108.2 0.0 5e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KOS23396.1 - 0.00027 20.0 0.0 0.0025 16.9 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KOS23396.1 - 0.00028 19.9 0.0 0.0006 18.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS23396.1 - 0.025 14.3 0.0 0.17 11.6 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KOS23396.1 - 0.2 10.4 0.0 3.3 6.3 0.0 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase PK PF00224.16 KOS23397.1 - 2.2e-170 565.8 3.7 2.7e-170 565.5 2.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KOS23397.1 - 1.2e-31 108.6 0.0 3.1e-31 107.3 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KOS23397.1 - 1.4e-05 24.1 1.3 4.3e-05 22.5 0.5 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 KOS23397.1 - 0.032 13.1 0.0 0.28 10.0 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF1748 PF08520.5 KOS23398.1 - 1.3e-35 120.8 0.1 1.4e-35 120.6 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Syntaxin-6_N PF09177.6 KOS23399.1 - 0.0062 16.9 0.3 0.71 10.3 0.0 2.6 2 0 0 2 2 2 1 Syntaxin 6, N-terminal V_ATPase_I PF01496.14 KOS23399.1 - 0.041 11.7 0.6 2.7 5.7 0.1 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Filament PF00038.16 KOS23399.1 - 0.25 10.7 5.6 0.12 11.8 0.7 2.3 2 0 0 2 2 2 0 Intermediate filament protein APG6 PF04111.7 KOS23399.1 - 0.5 9.3 7.6 0.11 11.4 1.7 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 KOS23399.1 - 3 7.4 9.9 0.36 10.3 1.1 2.5 3 0 0 3 3 3 0 IncA protein DUF3115 PF11312.3 KOS23400.1 - 2.7e-83 279.4 0.0 6.2e-83 278.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3115) PWWP PF00855.12 KOS23401.1 - 0.057 13.6 0.1 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 PWWP domain Btz PF09405.5 KOS23402.1 - 6.5e-27 94.1 0.5 1.6e-26 92.8 0.3 1.7 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Syja_N PF02383.13 KOS23403.1 - 3.6e-47 160.6 0.0 3.4e-27 95.0 0.0 2.3 1 1 1 2 2 2 2 SacI homology domain hSac2 PF12456.3 KOS23403.1 - 1.6e-30 104.8 0.0 2.8e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Nucleoplasmin PF03066.10 KOS23403.1 - 0.15 11.5 3.6 0.29 10.6 2.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin Fungal_trans_2 PF11951.3 KOS23404.1 - 1.3e-05 24.0 0.0 1.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAF-AH_p_II PF03403.8 KOS23405.1 - 1.3e-16 59.8 0.0 9.1e-09 34.0 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KOS23405.1 - 9.2e-11 41.6 0.0 1.4e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KOS23405.1 - 1.2e-07 30.9 0.0 3.4e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 KOS23405.1 - 1.7e-06 28.1 0.1 2.8e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KOS23405.1 - 0.0062 15.3 0.0 0.52 9.0 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase Hydrolase_4 PF12146.3 KOS23405.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 KOS23405.1 - 0.15 11.2 0.1 0.58 9.3 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family ATP-synt_C PF00137.16 KOS23406.1 - 1.6e-31 108.0 30.1 1.4e-18 66.5 8.6 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 KOS23406.1 - 0.23 11.0 4.5 0.093 12.2 0.9 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A ERG4_ERG24 PF01222.12 KOS23407.1 - 9.3e-136 452.7 20.5 1.1e-135 452.5 14.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Glyco_hydro_18 PF00704.23 KOS23408.1 - 2.8e-49 168.4 0.0 3.2e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 WD40 PF00400.27 KOS23409.1 - 2.3e-07 30.4 6.8 0.02 14.7 0.3 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat Sporozoite_P67 PF05642.6 KOS23409.1 - 0.00049 18.1 7.1 0.0024 15.8 3.3 2.2 2 0 0 2 2 2 1 Sporozoite P67 surface antigen Prothymosin PF03247.9 KOS23409.1 - 0.0027 17.8 29.2 0.0037 17.4 15.7 2.4 2 0 0 2 2 2 1 Prothymosin/parathymosin family DUF3326 PF11805.3 KOS23409.1 - 0.079 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) CDC27 PF09507.5 KOS23409.1 - 0.12 11.6 13.8 0.2 10.8 9.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 U79_P34 PF03064.11 KOS23409.1 - 0.17 11.3 10.9 0.32 10.4 7.6 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Utp14 PF04615.8 KOS23409.1 - 0.9 7.6 17.4 1.6 6.7 12.0 1.3 1 0 0 1 1 1 0 Utp14 protein CENP-T PF15511.1 KOS23409.1 - 1.1 8.3 16.5 0.22 10.7 8.0 1.9 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 KOS23409.1 - 2.8 5.8 24.8 0.26 9.2 13.1 1.8 2 0 0 2 2 2 0 CDC45-like protein eIF-3c_N PF05470.7 KOS23409.1 - 7 4.6 14.2 13 3.7 9.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CobT PF06213.7 KOS23409.1 - 7.5 5.5 30.6 0.083 12.0 14.7 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT zf-DHHC PF01529.15 KOS23410.1 - 1.1e-30 106.2 0.0 2.2e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KOS23410.1 - 0.029 14.1 0.6 0.067 12.9 0.4 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily DZR PF12773.2 KOS23410.1 - 0.14 12.0 7.8 0.26 11.1 5.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon Glyco_transf_90 PF05686.7 KOS23411.1 - 2.5e-07 29.7 0.0 0.0021 16.8 0.1 3.5 3 1 0 3 3 3 2 Glycosyl transferase family 90 PTCB-BRCT PF12738.2 KOS23412.1 - 0.0042 16.9 0.1 0.0099 15.7 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain SUZ PF12752.2 KOS23413.1 - 3 8.4 6.5 7.3 7.2 0.1 2.3 2 0 0 2 2 2 0 SUZ domain MSP1_C PF07462.6 KOS23413.1 - 4.1 5.6 5.8 4 5.7 4.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Oxidored_molyb PF00174.14 KOS23414.1 - 5e-44 149.7 0.0 1.2e-43 148.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KOS23414.1 - 2.3e-35 121.1 0.0 6e-35 119.7 0.0 1.7 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 KOS23414.1 - 5.5e-19 68.7 2.5 9.2e-19 68.0 0.0 2.7 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KOS23414.1 - 1.8e-16 59.7 0.2 4.5e-16 58.4 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 KOS23414.1 - 3.6e-16 59.0 0.0 5e-14 52.2 0.0 2.9 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain Hydrolase_3 PF08282.7 KOS23414.1 - 1.2 8.6 3.3 2.1 7.8 2.3 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FKBP_C PF00254.23 KOS23415.1 - 2.4e-33 113.9 0.0 3.1e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RPEL PF02755.10 KOS23416.1 - 7.1e-19 66.5 3.6 2.3e-09 36.2 0.2 2.4 2 0 0 2 2 2 2 RPEL repeat Myosin_head PF00063.16 KOS23417.1 - 7.1e-234 777.9 2.2 1.3e-233 777.0 1.6 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KOS23417.1 - 5.7e-40 136.7 0.0 1.4e-39 135.4 0.0 1.7 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 KOS23417.1 - 6.5e-12 44.6 0.3 1.4e-11 43.5 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KOS23417.1 - 2.6e-10 39.6 0.1 8.4e-10 38.0 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KOS23417.1 - 1.6e-08 33.8 0.0 7.7e-08 31.7 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain IQ PF00612.22 KOS23417.1 - 0.0015 17.9 9.7 0.04 13.5 1.7 2.7 1 1 1 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KOS23417.1 - 0.0076 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Hpr_kinase_C PF07475.7 KOS23417.1 - 0.018 14.3 0.2 2.2 7.5 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF552 PF04472.7 KOS23417.1 - 0.025 14.4 0.2 0.089 12.7 0.0 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF552) Zeta_toxin PF06414.7 KOS23417.1 - 0.026 13.6 0.0 0.063 12.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KOS23417.1 - 0.055 13.7 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KOS23417.1 - 0.057 13.0 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 KOS23417.1 - 0.073 13.8 0.0 0.3 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain DAHP_synth_2 PF01474.11 KOS23418.1 - 3.9e-192 638.4 0.0 4.4e-192 638.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Aldose_epim PF01263.15 KOS23419.1 - 1.1e-37 129.8 0.0 1.2e-37 129.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Peptidase_M24 PF00557.19 KOS23420.1 - 2.2e-46 158.0 0.1 2.7e-46 157.7 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KOS23420.1 - 6.2e-05 22.7 4.5 6.2e-05 22.7 3.1 2.1 2 0 0 2 2 2 1 MYND finger DUF3506 PF12014.3 KOS23421.1 - 1.1e-41 141.8 0.0 2.3e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 KOS23421.1 - 2.2e-05 24.0 0.1 4.4e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS23421.1 - 6.6e-05 22.4 0.0 0.00016 21.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain Serglycin PF04360.7 KOS23421.1 - 0.025 14.3 1.1 0.051 13.3 0.8 1.5 1 0 0 1 1 1 0 Serglycin CDC45 PF02724.9 KOS23422.1 - 0.087 10.8 11.6 0.19 9.7 8.0 1.6 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S8 PF00410.14 KOS23423.1 - 2.4e-21 75.9 0.0 4.5e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S8 FAD_binding_3 PF01494.14 KOS23423.1 - 1.5e-09 37.3 0.0 1.9e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 KOS23423.1 - 0.11 11.3 0.0 0.23 10.2 0.0 1.6 1 0 0 1 1 1 0 Squalene epoxidase Asp PF00026.18 KOS23424.1 - 4.4e-53 180.5 0.3 2.5e-50 171.5 0.2 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KOS23424.1 - 1.9e-06 27.9 1.6 5.3e-05 23.2 0.3 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KOS23424.1 - 0.0005 20.5 1.5 0.11 12.9 0.3 3.7 3 1 0 3 3 3 1 Aspartyl protease GTP_EFTU PF00009.22 KOS23425.1 - 1.2e-56 191.0 0.2 2.3e-56 190.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KOS23425.1 - 3.5e-32 110.0 0.0 7.5e-32 109.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KOS23425.1 - 4.3e-30 103.7 0.0 9.8e-30 102.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KOS23425.1 - 2.6e-22 78.4 0.0 6e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KOS23425.1 - 2.5e-13 49.9 0.0 6.1e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MobB PF03205.9 KOS23425.1 - 0.029 14.0 0.0 5.7 6.6 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF442 PF04273.8 KOS23425.1 - 0.064 13.1 0.0 1.5 8.6 0.0 2.8 2 0 0 2 2 2 0 Putative phosphatase (DUF442) DUF148 PF02520.12 KOS23425.1 - 0.14 11.9 0.3 0.33 10.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 ABC2_membrane PF01061.19 KOS23426.1 - 6.7e-37 126.7 17.1 6.7e-37 126.7 11.8 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KOS23426.1 - 6e-25 88.1 0.0 1.3e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KOS23426.1 - 2.7e-09 37.3 0.0 4.5e-08 33.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 KOS23426.1 - 1.8e-05 23.9 26.5 6.5e-05 22.1 18.4 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 KOS23426.1 - 0.00023 20.6 0.0 0.0098 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KOS23426.1 - 0.0026 17.2 0.1 0.006 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KOS23426.1 - 0.004 16.3 0.0 0.0087 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KOS23426.1 - 0.014 15.7 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KOS23426.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KOS23426.1 - 0.055 13.1 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 KOS23426.1 - 0.06 14.1 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 KOS23426.1 - 0.066 12.4 0.0 0.69 9.0 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KOS23426.1 - 0.068 12.1 0.0 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.20 KOS23426.1 - 0.088 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 KOS23426.1 - 0.096 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KOS23426.1 - 0.11 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KOS23426.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KOS23426.1 - 0.12 12.6 0.5 0.24 11.6 0.4 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KOS23426.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.16 KOS23427.1 - 4.4e-42 144.3 0.0 5.8e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KOS23427.1 - 1.1e-08 34.6 0.0 1.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KOS23427.1 - 7.5e-07 27.7 0.0 1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KOS23427.1 - 1.3e-06 27.4 0.0 1.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_MocR PF12897.2 KOS23427.1 - 6.2e-06 25.0 0.0 8.9e-06 24.5 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 KOS23427.1 - 0.00063 18.8 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 KOS23427.1 - 0.0036 15.9 0.1 0.011 14.4 0.1 1.6 1 1 0 1 1 1 1 Allinase NGP1NT PF08153.7 KOS23428.1 - 1.9e-47 160.4 0.1 2.8e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KOS23428.1 - 6.2e-19 68.0 0.1 1.7e-14 53.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 KOS23428.1 - 2.2e-05 24.3 1.0 0.018 14.8 0.1 3.4 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.13 KOS23428.1 - 3.3e-05 23.2 0.0 0.0002 20.6 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KOS23428.1 - 0.00019 20.9 0.1 0.14 11.5 0.0 3.3 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KOS23428.1 - 0.00045 19.4 0.2 0.027 13.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arf PF00025.16 KOS23428.1 - 0.0033 16.6 0.1 0.86 8.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 KOS23428.1 - 0.0054 17.2 0.1 0.34 11.4 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein SAGA-Tad1 PF12767.2 KOS23429.1 - 0.087 12.4 2.7 0.16 11.6 1.9 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Sel1 PF08238.7 KOS23431.1 - 1.1e-11 45.0 27.4 2.5e-05 24.7 0.0 6.9 7 0 0 7 7 6 4 Sel1 repeat TPR_1 PF00515.23 KOS23431.1 - 0.0055 16.2 0.2 0.018 14.6 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KOS23431.1 - 0.011 15.3 2.2 0.13 11.9 0.0 2.8 3 0 0 3 3 3 0 TPR repeat SRP-alpha_N PF04086.8 KOS23431.1 - 0.038 13.3 14.9 0.08 12.3 10.4 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Mitofilin PF09731.4 KOS23431.1 - 0.068 11.8 16.4 0.1 11.1 11.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Mem_trans PF03547.13 KOS23431.1 - 0.19 9.9 0.3 0.23 9.7 0.2 1.1 1 0 0 1 1 1 0 Membrane transport protein TPR_8 PF13181.1 KOS23431.1 - 1.7 8.6 7.6 0.27 11.1 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ycf1 PF05758.7 KOS23431.1 - 2.2 5.8 16.7 3.1 5.3 11.5 1.1 1 0 0 1 1 1 0 Ycf1 eIF-3_zeta PF05091.7 KOS23431.1 - 3 6.3 20.3 5 5.6 14.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.2 KOS23431.1 - 4.2 4.9 24.4 5.9 4.4 16.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.7 KOS23431.1 - 7.8 6.2 20.0 14 5.4 13.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HEAT_2 PF13646.1 KOS23432.1 - 2.9e-21 75.5 12.3 7.9e-10 38.8 0.1 8.8 4 3 8 12 12 12 6 HEAT repeats HEAT PF02985.17 KOS23432.1 - 4.4e-17 60.5 20.6 0.00086 19.1 0.0 12.0 14 0 0 14 14 13 5 HEAT repeat HEAT_EZ PF13513.1 KOS23432.1 - 4e-16 58.9 25.6 1.7e-08 34.7 0.1 10.5 10 1 2 12 12 12 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KOS23432.1 - 4e-12 46.3 2.5 0.0087 16.4 0.0 8.2 5 3 4 9 9 9 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 KOS23432.1 - 2.4e-09 37.0 0.0 0.011 15.4 0.1 5.6 3 2 2 5 5 5 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 KOS23432.1 - 9.4e-09 34.9 0.8 0.0022 17.3 0.4 5.7 5 1 1 6 6 6 2 CLASP N terminal MMS19_C PF12460.3 KOS23432.1 - 2.5e-08 33.0 4.3 3e-06 26.2 0.1 4.4 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.2 KOS23432.1 - 2.8e-06 27.3 2.5 2.8 7.7 0.0 5.5 3 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 KOS23432.1 - 0.00016 20.0 0.5 0.00076 17.8 0.1 2.3 2 2 1 3 3 3 1 Proteasome non-ATPase 26S subunit V-ATPase_H_N PF03224.9 KOS23432.1 - 0.0017 17.5 4.9 0.13 11.3 0.1 3.3 2 1 0 2 2 2 1 V-ATPase subunit H Telomere_reg-2 PF10193.4 KOS23432.1 - 0.0088 16.2 1.1 0.053 13.7 0.4 2.6 2 0 0 2 2 2 1 Telomere length regulation protein CAS_CSE1 PF03378.10 KOS23432.1 - 0.0097 14.2 0.5 1.3 7.2 0.1 4.1 4 2 0 5 5 5 1 CAS/CSE protein, C-terminus DUF4042 PF13251.1 KOS23432.1 - 0.017 14.6 0.5 18 4.7 0.0 5.0 5 1 2 7 7 7 0 Domain of unknown function (DUF4042) Cohesin_HEAT PF12765.2 KOS23432.1 - 0.031 14.2 0.0 13 5.8 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion TFCD_C PF12612.3 KOS23432.1 - 0.032 13.6 0.1 1.3 8.4 0.0 3.6 3 1 0 3 3 3 0 Tubulin folding cofactor D C terminal DRIM PF07539.7 KOS23432.1 - 0.073 12.4 0.6 0.24 10.8 0.4 1.9 1 0 0 1 1 1 0 Down-regulated in metastasis Arm PF00514.18 KOS23432.1 - 0.14 12.0 11.2 1.8 8.5 0.0 5.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat TAN PF11640.3 KOS23432.1 - 0.16 11.7 5.4 0.13 11.9 0.2 3.4 3 1 0 3 3 2 0 Telomere-length maintenance and DNA damage repair CBS PF00571.23 KOS23433.1 - 8.6e-18 63.8 1.8 3.5e-05 23.5 0.1 4.7 5 0 0 5 5 5 4 CBS domain NYN PF01936.13 KOS23434.1 - 0.0048 17.1 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 NYN domain SAC3_GANP PF03399.11 KOS23435.1 - 6.4e-25 87.9 0.0 8.5e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KOS23435.1 - 4.7e-21 75.0 0.0 7e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 PAS_9 PF13426.1 KOS23436.1 - 4.2e-27 94.5 0.0 4e-19 68.9 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 KOS23436.1 - 1.1e-15 57.4 0.0 1.9e-11 43.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 KOS23436.1 - 8.4e-14 51.3 0.0 1.2e-06 28.2 0.0 3.1 2 1 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KOS23436.1 - 2e-05 24.6 0.0 0.0023 17.9 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 KOS23436.1 - 0.00067 19.5 0.2 0.0022 17.9 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.1 KOS23436.1 - 0.059 13.2 0.0 0.7 9.8 0.0 2.3 2 0 0 2 2 2 0 PAS domain FAM101 PF15068.1 KOS23436.1 - 0.1 11.9 1.2 0.23 10.8 0.9 1.5 1 0 0 1 1 1 0 FAM101 family Med8 PF10232.4 KOS23437.1 - 2.1e-25 89.5 4.4 2.9e-25 89.1 3.1 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Rotamase PF00639.16 KOS23437.1 - 0.0017 19.0 0.0 0.0067 17.1 0.0 2.0 1 1 1 2 2 2 1 PPIC-type PPIASE domain CobT PF06213.7 KOS23437.1 - 0.0027 16.8 6.0 0.0038 16.3 4.2 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT NACHT PF05729.7 KOS23437.1 - 0.017 14.7 0.8 0.023 14.3 0.5 1.2 1 0 0 1 1 1 0 NACHT domain RasGEF_N_2 PF14663.1 KOS23437.1 - 0.026 14.4 0.1 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3245 PF11595.3 KOS23437.1 - 0.038 14.2 2.7 0.066 13.4 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) DUF2201_N PF13203.1 KOS23437.1 - 0.083 12.0 1.7 0.13 11.3 1.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Bd3614_N PF14442.1 KOS23437.1 - 0.43 10.5 4.3 0.67 9.9 3.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal DUF2457 PF10446.4 KOS23437.1 - 0.58 8.8 13.5 0.79 8.3 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 KOS23437.1 - 1.3 7.9 4.1 1.8 7.4 2.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.7 KOS23437.1 - 2.4 7.3 10.2 3.4 6.8 7.1 1.1 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 KOS23437.1 - 8.8 5.8 14.8 15 5.0 10.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_r4_2 PF08281.7 KOS23438.1 - 0.011 15.2 0.2 0.02 14.3 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_32 PF13565.1 KOS23438.1 - 0.41 11.4 4.0 3.1 8.6 2.7 2.2 1 1 0 1 1 1 0 Homeodomain-like domain ABC_membrane_2 PF06472.10 KOS23439.1 - 6e-98 327.4 0.4 6e-98 327.4 0.2 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KOS23439.1 - 5.6e-16 59.0 0.0 1.2e-15 58.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KOS23439.1 - 0.014 15.3 0.0 0.047 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain TAF4 PF05236.9 KOS23439.1 - 0.021 14.1 2.6 0.16 11.2 0.1 2.2 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family ALIX_LYPXL_bnd PF13949.1 KOS23439.1 - 0.026 13.4 0.1 0.042 12.7 0.1 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV AAA_17 PF13207.1 KOS23439.1 - 0.049 14.4 0.1 0.22 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KOS23439.1 - 0.054 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.7 KOS23439.1 - 0.056 12.4 0.0 0.14 11.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mei5 PF10376.4 KOS23439.1 - 0.098 12.1 0.9 0.17 11.3 0.6 1.3 1 0 0 1 1 1 0 Double-strand recombination repair protein Sigma54_activ_2 PF14532.1 KOS23439.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain THOC7 PF05615.8 KOS23439.1 - 0.13 12.5 2.6 0.28 11.4 1.8 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 T2SE PF00437.15 KOS23439.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.16 KOS23439.1 - 0.17 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 KOS23439.1 - 5.2 7.3 10.7 1.6e+02 2.4 7.5 2.4 1 1 0 1 1 1 0 AAA domain NIF PF03031.13 KOS23440.1 - 1.7e-51 174.0 0.2 2.5e-51 173.4 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4597 PF15366.1 KOS23440.1 - 0.035 13.6 0.7 0.035 13.6 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4597) Pkinase_Tyr PF07714.12 KOS23441.1 - 0.001 18.2 0.0 0.14 11.2 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.20 KOS23441.1 - 0.0013 17.9 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain RNase_P_p30 PF01876.11 KOS23443.1 - 3.8e-46 156.0 0.0 5.9e-46 155.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Sulfatase PF00884.18 KOS23444.1 - 3.9e-55 187.2 0.0 5.5e-52 176.8 0.0 2.1 1 1 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 KOS23444.1 - 1.9e-12 46.8 2.0 7.2e-12 44.9 0.1 2.7 2 1 1 3 3 3 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 KOS23444.1 - 1e-08 34.9 0.1 1e-05 25.0 0.1 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KOS23444.1 - 1.9e-05 23.2 0.0 2.8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 KOS23444.1 - 0.022 15.0 0.1 0.056 13.7 0.1 1.7 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Tox-HDC PF15656.1 KOS23444.1 - 0.18 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature DUF1501 PF07394.7 KOS23444.1 - 0.24 10.2 0.6 0.4 9.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) Sec61_beta PF03911.11 KOS23445.1 - 7.5e-21 73.6 1.2 9.6e-21 73.3 0.8 1.1 1 0 0 1 1 1 1 Sec61beta family Glyco_transf_28 PF03033.15 KOS23446.1 - 9.3e-21 74.0 0.2 5.5e-20 71.5 0.1 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KOS23446.1 - 0.00052 18.6 0.7 0.00076 18.1 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 KOS23446.1 - 0.00053 20.0 0.0 0.0017 18.4 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain Glyco_tran_28_C PF04101.11 KOS23446.1 - 0.0075 15.9 0.2 0.026 14.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain UIM PF02809.15 KOS23446.1 - 0.014 14.8 0.3 0.014 14.8 0.2 4.0 4 0 0 4 4 4 0 Ubiquitin interaction motif PCI PF01399.22 KOS23447.1 - 2.1e-07 31.2 0.1 6.6e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 PCI domain VP9 PF09625.5 KOS23447.1 - 0.015 15.1 0.0 0.044 13.5 0.0 1.8 1 0 0 1 1 1 0 VP9 protein Apc5 PF12862.2 KOS23447.1 - 0.019 14.7 6.6 0.23 11.3 0.4 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 NmrA PF05368.8 KOS23448.1 - 0.054 12.7 0.1 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Lactamase_B PF00753.22 KOS23449.1 - 1.5e-23 83.4 1.4 1.9e-23 83.1 0.9 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KOS23449.1 - 8e-05 22.2 0.1 0.00012 21.6 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KOS23449.1 - 0.00042 20.0 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Rsa3 PF14615.1 KOS23450.1 - 2.4e-18 65.1 0.6 3.9e-18 64.4 0.3 1.4 1 1 1 2 2 2 1 Ribosome-assembly protein 3 IFT57 PF10498.4 KOS23450.1 - 0.0097 14.6 0.7 0.0097 14.6 0.5 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Glu-tRNAGln PF02686.10 KOS23450.1 - 0.04 13.7 0.3 0.089 12.6 0.2 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit UAF_Rrn10 PF05234.6 KOS23450.1 - 0.049 13.6 0.0 0.059 13.4 0.0 1.1 1 0 0 1 1 1 0 UAF complex subunit Rrn10 NAD_synthase PF02540.12 KOS23451.1 - 0.058 12.2 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 NAD synthase UCH PF00443.24 KOS23452.1 - 3.4e-07 29.6 0.2 3.5e-07 29.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HATPase_c PF02518.21 KOS23453.1 - 4.2e-25 87.6 0.4 9.1e-25 86.5 0.3 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KOS23453.1 - 2.1e-21 76.0 0.6 2.8e-20 72.3 0.1 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KOS23453.1 - 1.3e-20 73.1 0.1 4e-20 71.5 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 KOS23453.1 - 5.1e-08 32.8 0.1 0.0022 18.0 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 KOS23453.1 - 0.00031 21.0 0.0 0.16 12.3 0.0 3.1 3 0 0 3 3 3 1 PAS domain PAS PF00989.19 KOS23453.1 - 0.0022 17.7 0.0 0.0071 16.1 0.0 1.8 1 0 0 1 1 1 1 PAS fold Allantoicase PF03561.10 KOS23454.1 - 9.2e-104 343.3 0.0 6.7e-55 184.7 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ank_2 PF12796.2 KOS23455.1 - 3.5e-18 65.7 0.0 2e-17 63.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DIL PF01843.14 KOS23455.1 - 5.3e-18 64.8 0.9 1e-11 44.6 0.2 2.5 2 0 0 2 2 2 2 DIL domain Ank PF00023.25 KOS23455.1 - 1.3e-15 56.3 0.0 2.5e-06 27.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KOS23455.1 - 5.4e-13 49.0 0.0 1.1e-05 25.7 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KOS23455.1 - 1.5e-11 44.1 0.0 3.8e-08 33.3 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS23455.1 - 2.8e-10 39.4 0.0 0.0037 17.3 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Cytochrom_B561 PF03188.11 KOS23456.1 - 6.7e-16 58.3 6.0 7.2e-16 58.2 3.5 1.5 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 PepSY_TM_1 PF13172.1 KOS23456.1 - 0.0022 17.6 6.7 0.006 16.2 0.7 3.0 2 0 0 2 2 2 1 PepSY-associated TM helix DUF4079 PF13301.1 KOS23456.1 - 0.018 15.0 19.8 0.34 10.9 2.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) DUF420 PF04238.7 KOS23456.1 - 0.079 12.9 5.7 0.2 11.5 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF420) Sensor_TM1 PF13755.1 KOS23456.1 - 0.13 11.8 3.4 4.9 6.7 2.4 2.4 1 1 0 1 1 1 0 Sensor N-terminal transmembrane domain DUF4149 PF13664.1 KOS23456.1 - 1.2 9.2 15.2 0.091 12.8 2.8 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) HPP PF04982.8 KOS23456.1 - 1.5 8.6 12.6 5.9 6.7 8.7 2.0 1 1 0 1 1 1 0 HPP family DUF4153 PF13687.1 KOS23456.1 - 3.1 7.2 10.2 0.49 9.8 1.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4153) DUF1168 PF06658.7 KOS23457.1 - 3.6e-36 123.7 16.2 3.6e-36 123.7 11.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1168) GRP PF07172.6 KOS23457.1 - 2.6 8.5 14.5 4.6 7.7 10.1 1.5 1 0 0 1 1 1 0 Glycine rich protein family His_Phos_1 PF00300.17 KOS23458.1 - 4.3e-34 117.8 0.2 3.2e-33 115.0 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KOS23458.1 - 0.00051 19.4 0.0 0.0013 18.1 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RRN9 PF10680.4 KOS23458.1 - 0.16 11.7 1.7 0.97 9.2 0.2 2.7 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor HET PF06985.6 KOS23459.1 - 7.2e-16 58.6 0.0 1.3e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cpn60_TCP1 PF00118.19 KOS23460.1 - 9.1e-164 545.6 0.3 1e-163 545.4 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.9 KOS23461.1 - 4.7e-39 134.3 0.3 6.7e-39 133.8 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KOS23461.1 - 2.2e-33 114.5 0.0 3.7e-32 110.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KOS23461.1 - 4.2e-18 65.5 1.4 4.1e-16 59.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KOS23461.1 - 1.2e-10 41.7 0.1 3.3e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KOS23461.1 - 0.0062 15.4 0.0 0.0099 14.8 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KOS23461.1 - 0.0087 14.9 0.3 0.043 12.6 0.1 2.1 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 KOS23461.1 - 0.037 13.1 0.2 0.075 12.1 0.2 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KOS23461.1 - 0.077 11.8 4.8 2.9 6.6 1.6 2.8 3 0 0 3 3 3 0 FAD binding domain HI0933_like PF03486.9 KOS23461.1 - 0.12 10.8 0.5 7 4.9 0.8 2.7 3 0 0 3 3 3 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 KOS23461.1 - 0.2 10.7 2.8 0.6 9.2 0.0 2.6 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KOS23461.1 - 0.33 10.5 0.0 0.33 10.5 0.0 2.3 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ecl1 PF12855.2 KOS23462.1 - 1.6e-09 36.9 1.4 2.9e-09 36.0 1.0 1.5 1 0 0 1 1 1 1 Life-span regulatory factor DUF2116 PF09889.4 KOS23462.1 - 0.058 13.2 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF329 PF03884.9 KOS23462.1 - 0.14 11.7 2.6 0.3 10.6 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-MYND PF01753.13 KOS23462.1 - 0.17 11.8 2.1 0.45 10.4 1.4 1.7 1 0 0 1 1 1 0 MYND finger Metallothio_Pro PF02069.11 KOS23462.1 - 0.78 9.6 3.6 0.27 11.0 0.7 1.6 2 0 0 2 2 2 0 Prokaryotic metallothionein DENN PF02141.16 KOS23463.1 - 2.8e-41 141.2 0.0 4.4e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain Elongin_A PF06881.6 KOS23463.1 - 0.00083 19.7 3.2 0.00083 19.7 2.2 2.3 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DivIVA PF05103.8 KOS23463.1 - 0.47 10.5 16.1 0.62 10.1 6.4 2.6 1 1 1 2 2 2 0 DivIVA protein DUF2570 PF10828.3 KOS23463.1 - 0.65 9.6 8.9 1.1 8.8 5.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2570)