# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- COX2 PF00116.15 AAS50168.1 - 1.1e-51 173.6 0.1 1.7e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.10 AAS50168.1 - 1.3e-30 105.1 6.4 2.8e-30 104.0 4.5 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain COX1 PF00115.15 AAS50169.1 - 3.1e-164 546.8 58.0 3.9e-164 546.5 40.2 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX3 PF00510.13 AAS50170.1 - 8.8e-109 362.8 27.4 1e-108 362.7 19.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III DUF3937 PF13073.1 AAS50170.1 - 0.0002 21.2 1.1 0.005 16.7 0.1 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3937) VAR1 PF05316.7 AAS50171.1 - 9.8e-42 142.7 141.8 1.8e-41 141.8 98.2 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein (VAR1) Ribosomal_S3_C PF00189.15 AAS50171.1 - 0.031 14.4 1.2 0.031 14.4 0.8 2.4 2 1 0 2 2 2 0 Ribosomal protein S3, C-terminal domain Fun_ATP-synt_8 PF05933.8 AAS50172.1 - 9.4e-18 63.9 14.2 1e-17 63.8 9.9 1.0 1 0 0 1 1 1 1 Fungal ATP synthase protein 8 (A6L) ATP-synt_A PF00119.15 AAS50173.1 - 3.2e-56 190.2 37.9 3.9e-56 189.9 26.3 1.0 1 0 0 1 1 1 1 ATP synthase A chain ATP-synt_C PF00137.16 AAS50174.1 - 5.2e-19 67.9 11.3 5.9e-19 67.7 7.8 1.0 1 0 0 1 1 1 1 ATP synthase subunit C ABC2_membrane_4 PF12730.2 AAS50174.1 - 0.072 12.2 8.8 0.088 11.9 6.1 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_5 PF13346.1 AAS50174.1 - 0.2 10.9 5.0 0.22 10.8 3.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Cytochrom_B_N_2 PF13631.1 AAS50175.1 - 4.3e-51 173.0 21.3 4.3e-51 173.0 14.8 3.2 3 1 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.12 AAS50175.1 - 3.5e-36 123.4 2.8 3.5e-36 123.4 1.9 3.8 2 1 3 5 5 5 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_N PF00033.14 AAS50175.1 - 5e-15 55.3 19.3 5e-15 55.3 13.3 2.4 2 1 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Abi PF02517.11 AAS50180.1 - 6.3e-15 55.0 3.1 6.3e-15 55.0 2.1 1.9 2 0 0 2 2 2 1 CAAX protease self-immunity DUF2628 PF10947.3 AAS50180.1 - 0.45 10.3 4.4 1.6 8.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) Zds_C PF08632.5 AAS50181.1 - 6.2e-34 115.1 2.2 1.3e-33 114.1 1.5 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF1892 PF08987.5 AAS50182.1 - 7.7e-48 161.2 2.5 8.6e-48 161.1 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1892) Cyt-b5 PF00173.23 AAS50183.1 - 7.5e-20 70.5 0.7 8.8e-19 67.0 0.1 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 AAS50183.1 - 1.8e-10 41.2 15.9 1.8e-10 41.2 11.0 2.2 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 AAS50183.1 - 0.084 12.8 0.2 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region SMC_N PF02463.14 AAS50184.1 - 1.1e-61 207.9 13.4 1.7e-61 207.2 9.3 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AAS50184.1 - 1.8e-29 102.1 1.0 1.1e-28 99.5 0.0 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AAS50184.1 - 1.1e-09 38.6 17.9 2.8e-07 30.7 2.6 3.8 2 2 0 2 2 2 2 AAA domain AAA_23 PF13476.1 AAS50184.1 - 0.0011 19.4 48.5 0.0011 19.4 33.6 7.6 2 2 3 5 5 5 1 AAA domain TPR_MLP1_2 PF07926.7 AAS50184.1 - 0.0034 17.1 13.6 0.0034 17.1 9.4 8.2 3 2 3 6 6 6 1 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 AAS50184.1 - 0.0036 17.4 10.9 0.0036 17.4 7.5 9.1 6 3 5 11 11 11 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_29 PF13555.1 AAS50184.1 - 0.0061 16.0 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Cytokin_check_N PF10407.4 AAS50185.1 - 8.5e-32 108.6 0.3 6.3e-31 105.8 0.1 2.2 2 0 0 2 2 2 1 Cdc14 phosphatase binding protein N-terminus CAP PF00188.21 AAS50187.1 - 3.5e-20 72.7 0.1 7.2e-20 71.7 0.1 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PAT1 PF09770.4 AAS50187.1 - 4.9 5.2 13.3 6.4 4.8 9.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAP PF00188.21 AAS50188.1 - 3.1e-23 82.5 0.7 4.5e-23 82.0 0.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Bystin PF05291.6 AAS50188.1 - 0.025 13.5 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 Bystin KH_1 PF00013.24 AAS50189.1 - 9.1e-82 268.6 34.2 9.2e-13 47.6 0.3 11.5 11 0 0 11 11 11 8 KH domain KH_3 PF13014.1 AAS50189.1 - 2.4e-48 161.0 29.4 2.2e-08 33.5 0.0 10.3 9 1 0 9 9 9 7 KH domain KH_2 PF07650.12 AAS50189.1 - 6.2e-13 48.1 20.6 0.00091 18.7 0.6 7.0 5 1 1 6 6 6 5 KH domain SLS PF14611.1 AAS50189.1 - 5.5e-08 32.4 17.2 0.41 10.0 0.0 8.6 4 4 6 10 10 10 3 Mitochondrial inner-membrane-bound regulator BMC PF00936.14 AAS50189.1 - 9.9e-07 28.3 1.5 0.1 12.2 0.0 6.2 6 0 0 6 6 6 1 BMC domain KH_4 PF13083.1 AAS50189.1 - 4.4e-06 26.2 0.8 0.21 11.2 0.0 5.5 5 0 0 5 5 5 1 KH domain KH_5 PF13184.1 AAS50189.1 - 0.00028 20.6 20.6 1.6 8.6 0.1 6.8 7 0 0 7 7 7 3 NusA-like KH domain Ras PF00071.17 AAS50190.1 - 2.3e-53 179.8 0.1 2.7e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS50190.1 - 2.4e-21 76.4 0.1 3.7e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS50190.1 - 2.6e-14 52.8 0.0 3.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AAS50190.1 - 2.6e-08 33.3 0.0 3.6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AAS50190.1 - 2.8e-05 23.6 0.0 6e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AAS50190.1 - 7.1e-05 22.7 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 AAS50190.1 - 0.056 12.1 0.5 2.5 6.7 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 AAS50190.1 - 0.066 13.1 0.1 0.099 12.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 AAS50190.1 - 0.097 11.8 0.1 0.32 10.1 0.0 1.7 1 1 0 2 2 2 0 Protein of unknown function, DUF258 Hpr_kinase_C PF07475.7 AAS50190.1 - 0.12 11.6 0.1 5 6.4 0.0 2.1 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Fungal_trans_2 PF11951.3 AAS50191.1 - 3.6e-113 378.0 4.4 4.5e-113 377.7 3.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS50191.1 - 3.5e-13 49.2 5.5 9e-13 47.9 3.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamin_M PF01031.15 AAS50192.1 - 1.8e-112 374.9 0.0 2.8e-112 374.3 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 AAS50192.1 - 3.1e-54 183.2 0.4 1.3e-53 181.3 0.0 2.2 2 1 0 2 2 2 1 Dynamin family GED PF02212.13 AAS50192.1 - 2.2e-29 101.1 0.6 6.2e-29 99.7 0.4 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 AAS50192.1 - 0.00045 20.1 0.1 0.0034 17.3 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AAS50192.1 - 0.016 15.6 0.0 0.068 13.6 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein zf-CCHC_4 PF14392.1 AAS50192.1 - 0.045 13.4 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle KAT11 PF08214.6 AAS50193.1 - 6.6e-90 301.6 0.0 7.5e-90 301.4 0.0 1.0 1 0 0 1 1 1 1 Histone acetylation protein Proteasome PF00227.21 AAS50194.1 - 6.3e-48 162.5 0.4 7.1e-48 162.4 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Sfi1_C PF10638.4 AAS50195.1 - 6.6e-43 145.5 3.2 2.9e-42 143.4 2.2 2.2 1 0 0 1 1 1 1 Spindle body associated protein C-terminus Sfi1 PF08457.5 AAS50195.1 - 1.2e-25 89.9 71.3 2.4e-22 79.0 34.7 2.7 1 1 1 2 2 2 2 Sfi1 spindle body protein EF1G PF00647.14 AAS50195.1 - 0.01 15.5 15.3 0.017 14.8 0.4 4.9 4 0 0 4 4 4 0 Elongation factor 1 gamma, conserved domain Ribophorin_I PF04597.9 AAS50196.1 - 6.6e-131 436.7 0.1 7.5e-131 436.5 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I ORC3_N PF07034.6 AAS50197.1 - 7.2e-08 31.7 0.8 4.2e-07 29.2 0.5 2.1 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus COX16 PF14138.1 AAS50198.1 - 8.1e-30 102.8 0.0 1.2e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DUF221 PF02714.10 AAS50199.1 - 1.1e-89 300.5 25.2 1.1e-89 300.5 17.4 3.0 5 0 0 5 5 5 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AAS50199.1 - 5.4e-28 97.5 2.9 5.4e-28 97.5 2.0 2.9 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 AAS50199.1 - 4.8e-07 29.5 0.0 1.5e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF3839 PF12943.2 AAS50199.1 - 0.088 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) DUF2404 PF10296.4 AAS50200.1 - 5.4e-05 23.2 0.0 0.00014 21.8 0.0 1.8 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DEAD PF00270.24 AAS50202.1 - 6.5e-45 152.6 0.1 1.9e-44 151.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS50202.1 - 2.7e-25 88.0 0.0 7e-25 86.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AAS50202.1 - 0.17 12.0 3.9 0.14 12.3 0.2 2.7 3 1 0 3 3 3 0 AAA domain SYS1 PF09801.4 AAS50203.1 - 8.5e-51 171.7 14.5 1e-50 171.5 10.0 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network LRR_8 PF13855.1 AAS50204.1 - 2.6e-48 161.6 74.1 2.4e-10 40.0 3.7 9.7 8 2 2 10 10 10 8 Leucine rich repeat PP2C PF00481.16 AAS50204.1 - 4e-47 160.7 0.2 6.6e-47 160.0 0.2 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 AAS50204.1 - 2.3e-40 135.5 85.8 9.7e-08 31.4 1.5 13.7 4 2 10 15 15 15 12 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.15 AAS50204.1 - 2.1e-26 92.4 0.0 4.2e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 AAS50204.1 - 1.5e-18 63.9 73.9 0.051 13.6 0.1 19.4 17 1 1 18 18 18 9 Leucine Rich Repeat RA PF00788.18 AAS50204.1 - 1e-08 35.5 0.0 2.6e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 AAS50204.1 - 7.7e-08 31.3 65.7 0.12 12.6 0.4 16.6 18 0 0 18 18 18 5 Leucine rich repeat LRR_9 PF14580.1 AAS50204.1 - 0.023 14.2 22.8 0.0089 15.6 2.3 5.2 3 1 1 5 5 5 0 Leucine-rich repeat DUF2065 PF09838.4 AAS50204.1 - 0.42 10.3 0.3 1.3 8.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) COX17 PF05051.8 AAS50205.1 - 1.5e-21 76.1 5.8 1.8e-21 75.9 4.0 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 AAS50205.1 - 0.00073 19.2 3.1 0.01 15.6 0.1 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 AAS50205.1 - 0.011 15.5 2.0 0.017 15.0 1.4 1.4 1 0 0 1 1 1 0 CHCH domain PNP_UDP_1 PF01048.15 AAS50206.1 - 4e-35 120.8 0.0 4.8e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NiFe_hyd_SSU_C PF14720.1 AAS50206.1 - 0.072 13.1 0.0 5.1 7.1 0.0 2.3 2 0 0 2 2 2 0 NiFe/NiFeSe hydrogenase small subunit C-terminal NPCC PF08058.6 AAS50207.1 - 1.1e-41 141.9 0.7 1.5e-41 141.5 0.5 1.2 1 0 0 1 1 1 1 Nuclear pore complex component NIF PF03031.13 AAS50208.1 - 1.1e-49 168.1 0.2 1.6e-49 167.5 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WD40 PF00400.27 AAS50209.1 - 6e-35 117.8 3.6 3.6e-09 36.1 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 AAS50209.1 - 4.4e-29 100.3 12.9 3.7e-28 97.3 9.6 2.0 2 0 0 2 2 2 1 Sof1-like domain BBS2_Mid PF14783.1 AAS50209.1 - 0.00052 19.7 0.2 0.046 13.5 0.0 3.4 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Abhydro_lipase PF04083.11 AAS50210.1 - 2e-15 55.8 0.0 3.5e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 AAS50210.1 - 6e-06 26.3 0.1 9.8e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AAS50210.1 - 0.0015 18.1 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 AAS50210.1 - 0.022 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3387 PF11867.3 AAS50210.1 - 0.088 11.7 0.4 0.14 11.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) chaperone_DMP PF10448.4 AAS50211.1 - 3.8e-46 156.5 0.0 4.2e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 20S proteasome chaperone SBDS_C PF09377.5 AAS50212.1 - 2e-39 134.1 0.4 4.4e-39 133.0 0.3 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 AAS50212.1 - 2e-32 110.8 2.0 3.1e-32 110.2 1.4 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HlyIII PF03006.15 AAS50213.1 - 5.6e-55 186.1 17.7 5.6e-55 186.1 12.3 1.4 2 0 0 2 2 2 1 Haemolysin-III related PUF PF00806.14 AAS50214.1 - 2.2e-52 171.6 11.4 5.7e-08 31.8 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Rab5ip PF07019.7 AAS50215.1 - 4.4e-21 74.8 2.0 5.2e-21 74.5 1.4 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF383 PF04063.9 AAS50216.1 - 1.4e-70 236.7 0.1 7.9e-70 234.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 AAS50216.1 - 8.8e-27 92.4 0.6 2.6e-26 90.9 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT_2 PF13646.1 AAS50216.1 - 0.037 14.3 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats GlutR_dimer PF00745.15 AAS50216.1 - 0.053 13.4 0.1 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain TFIIF_alpha PF05793.7 AAS50217.1 - 5.6e-13 48.1 35.8 2.4e-09 36.1 0.3 2.8 2 1 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Vac7 PF12751.2 AAS50217.1 - 0.023 13.5 0.4 0.043 12.6 0.3 1.4 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Ripply PF14998.1 AAS50217.1 - 0.095 12.8 0.3 26 4.9 0.1 3.0 2 0 0 2 2 2 0 Transcription Regulator tRNA-synt_1b PF00579.20 AAS50218.1 - 1.2e-72 244.5 0.0 1.6e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-UBR PF02207.15 AAS50219.2 - 4.1e-14 52.0 10.3 1.6e-13 50.1 7.2 2.0 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Cut8_M PF14483.1 AAS50219.2 - 0.056 13.2 0.1 6.1 6.7 0.0 3.1 3 0 0 3 3 3 0 Cut8 dimerisation domain zf-rbx1 PF12678.2 AAS50219.2 - 6.1 7.0 12.1 0.74 9.9 3.0 3.2 2 1 0 2 2 2 0 RING-H2 zinc finger zf-UBR PF02207.15 AAS50220.1 - 2.6e-17 62.3 12.5 2.6e-17 62.3 8.6 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 AAS50220.1 - 7.4e-09 35.2 0.0 2e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 AAS50220.1 - 1e-05 25.2 0.7 1e-05 25.2 0.5 3.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 AAS50220.1 - 0.0027 17.7 1.4 0.0027 17.7 0.9 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AAS50220.1 - 0.014 15.0 0.9 0.014 15.0 0.6 2.7 2 0 0 2 2 2 0 zinc-RING finger domain UCR_UQCRX_QCR9 PF05365.7 AAS50221.1 - 6.4e-30 102.5 1.5 7e-30 102.4 1.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-Tim10_DDP PF02953.10 AAS50222.1 - 2.7e-18 64.9 1.9 4.1e-18 64.4 1.3 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF4300 PF14133.1 AAS50222.1 - 0.07 12.3 0.2 0.081 12.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) Clat_adaptor_s PF01217.15 AAS50223.1 - 3.8e-57 191.9 1.8 4.5e-57 191.7 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ParD PF09386.5 AAS50223.1 - 0.091 12.9 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Antitoxin ParD CBP4 PF07960.6 AAS50224.2 - 1.4e-51 173.3 6.1 1.7e-51 173.1 4.3 1.0 1 0 0 1 1 1 1 CBP4 AIP3 PF03915.8 AAS50224.2 - 0.0031 16.4 3.3 0.0037 16.2 2.3 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 DUF342 PF03961.8 AAS50224.2 - 0.011 14.1 0.6 0.013 13.9 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Tmemb_161AB PF10268.4 AAS50224.2 - 0.035 12.6 0.0 0.047 12.2 0.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB Meckelin PF09773.4 AAS50224.2 - 0.34 8.6 1.8 0.5 8.0 1.1 1.3 1 1 0 1 1 1 0 Meckelin (Transmembrane protein 67) Asp-B-Hydro_N PF05279.6 AAS50224.2 - 0.46 10.3 5.2 0.61 9.8 3.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region UBN2 PF14223.1 AAS50224.2 - 0.64 9.8 8.2 4.9 6.9 1.4 2.1 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Atg14 PF10186.4 AAS50224.2 - 0.68 8.8 8.4 0.89 8.4 5.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2215 PF10225.4 AAS50224.2 - 0.89 8.9 4.7 0.35 10.2 0.3 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2215) Wbp11 PF09429.5 AAS50224.2 - 1.7 8.7 12.7 1.1 9.3 4.3 2.2 2 0 0 2 2 2 0 WW domain binding protein 11 60KD_IMP PF02096.15 AAS50224.2 - 4.5 6.8 5.4 15 5.1 0.1 2.1 2 0 0 2 2 2 0 60Kd inner membrane protein SE PF08491.5 AAS50225.1 - 1.2e-119 398.2 0.0 1.5e-119 397.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 AAS50225.1 - 9.1e-14 51.2 0.0 3.5e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 AAS50225.1 - 3.1e-06 26.3 0.2 1.1e-05 24.5 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AAS50225.1 - 0.00024 21.0 0.1 0.00057 19.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 AAS50225.1 - 0.00047 19.1 0.4 0.00081 18.3 0.1 1.4 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 AAS50225.1 - 0.00066 19.7 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 AAS50225.1 - 0.00086 19.2 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AAS50225.1 - 0.00091 18.3 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 AAS50225.1 - 0.00098 19.4 0.1 0.0023 18.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 AAS50225.1 - 0.0048 16.5 0.1 0.0074 15.9 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDI PF00996.13 AAS50225.1 - 0.0076 14.6 0.0 0.011 14.0 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor FAD_oxidored PF12831.2 AAS50225.1 - 0.018 14.1 0.8 0.033 13.2 0.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 AAS50225.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 AAS50225.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 AAS50225.1 - 0.088 11.6 0.2 0.13 11.1 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 AAS50225.1 - 0.096 12.0 0.1 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 AAS50225.1 - 0.099 11.0 0.2 0.26 9.6 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 AAS50225.1 - 0.17 11.8 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AAS50225.1 - 0.18 10.7 0.9 0.66 8.8 0.1 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein RRN7 PF11781.3 AAS50226.1 - 3.7e-09 35.9 0.6 6e-09 35.2 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 MarR_2 PF12802.2 AAS50226.1 - 0.026 14.1 2.2 0.026 14.1 0.2 2.0 3 0 0 3 3 3 0 MarR family GntR PF00392.16 AAS50226.1 - 0.031 13.7 0.2 0.063 12.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family ssDNA-exonuc_C PF10141.4 AAS50226.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain LsmAD PF06741.8 AAS50227.1 - 9.6e-30 102.5 2.0 1.1e-29 102.2 0.4 1.9 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 AAS50227.1 - 5.7e-15 55.0 0.5 1.8e-14 53.3 0.0 2.2 3 0 0 3 3 3 1 Ataxin 2 SM domain CENP-Q PF13094.1 AAS50228.1 - 0.0024 17.9 1.2 0.0045 17.0 0.8 1.5 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Arfaptin PF06456.8 AAS50228.1 - 0.046 13.0 0.2 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Arfaptin-like domain FdhE PF04216.7 AAS50228.1 - 0.15 11.7 9.0 1.9 8.1 2.6 2.1 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation Thi4 PF01946.12 AAS50229.1 - 5.3e-96 320.1 0.2 6.4e-96 319.8 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 AAS50229.1 - 1.1e-08 34.4 1.6 5.3e-08 32.1 0.2 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AAS50229.1 - 6.2e-07 29.3 0.7 3e-06 27.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 AAS50229.1 - 4.5e-06 26.5 1.0 7.1e-05 22.6 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 AAS50229.1 - 1.4e-05 24.1 1.8 0.00046 19.1 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 AAS50229.1 - 1.7e-05 23.9 0.4 2.7e-05 23.2 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 AAS50229.1 - 0.00015 21.9 0.1 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AAS50229.1 - 0.00072 19.4 2.8 0.0026 17.6 1.9 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AAS50229.1 - 0.0055 15.2 0.5 0.01 14.3 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 AAS50229.1 - 0.0056 15.8 0.1 0.0088 15.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AAS50229.1 - 0.016 14.3 0.1 0.028 13.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 AAS50229.1 - 0.024 13.4 0.2 0.1 11.4 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 AAS50229.1 - 0.024 13.2 0.3 0.037 12.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 AAS50229.1 - 0.079 12.6 0.3 0.23 11.1 0.1 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ribonuc_red_sm PF00268.16 AAS50230.1 - 2e-121 404.3 5.1 2.6e-121 403.9 3.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Yip1 PF04893.12 AAS50231.1 - 7.1e-06 25.6 19.0 1.7e-05 24.3 13.2 1.7 1 1 0 1 1 1 1 Yip1 domain TGS PF02824.16 AAS50232.1 - 2.1e-20 72.3 0.0 4.5e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 AAS50232.1 - 2.7e-20 72.4 0.3 1.2e-19 70.3 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AAS50232.1 - 1.3e-13 50.5 0.0 2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AAS50232.1 - 3.3e-05 23.7 0.6 0.0059 16.4 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 AAS50232.1 - 0.0003 21.2 0.1 0.00099 19.6 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 AAS50232.1 - 0.0038 16.3 0.1 0.0065 15.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 AAS50232.1 - 0.0047 16.1 0.4 0.015 14.5 0.1 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MCM PF00493.18 AAS50232.1 - 0.0089 14.8 0.0 0.019 13.7 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family GTP_EFTU PF00009.22 AAS50232.1 - 0.02 14.3 1.7 2.4 7.5 0.5 3.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Ras PF00071.17 AAS50232.1 - 0.032 13.6 0.5 0.9 8.9 0.1 2.3 2 0 0 2 2 2 0 Ras family tRNA-synt_1g PF09334.6 AAS50233.1 - 3.7e-106 355.0 0.0 4.8e-106 354.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AAS50233.1 - 2.2e-20 72.2 0.0 1e-09 36.9 0.0 3.3 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 AAS50233.1 - 6.6e-10 38.5 0.0 1.3e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 AAS50233.1 - 0.00082 19.1 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.13 AAS50233.1 - 0.0041 15.8 0.0 0.0068 15.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (K) DNA_pol_E_B PF04042.11 AAS50234.1 - 4.4e-42 143.6 0.0 6.8e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PS_Dcarbxylase PF02666.10 AAS50235.1 - 7.1e-54 182.1 0.0 1.1e-53 181.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 AAS50235.1 - 4.8e-17 61.5 1.2 9.5e-11 41.3 0.0 3.0 2 0 0 2 2 2 2 C2 domain DUF4355 PF14265.1 AAS50236.1 - 1.6 8.6 21.5 2.4 8.1 14.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) BTV_NS2 PF04514.7 AAS50236.1 - 2.9 6.6 9.8 3.3 6.5 6.8 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF572 PF04502.8 AAS50236.1 - 2.9 7.0 13.2 3 6.9 9.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) RapA_C PF12137.3 AAS50236.1 - 3.1 6.5 9.2 3.5 6.3 6.3 1.0 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal ARGLU PF15346.1 AAS50236.1 - 4.3 7.1 25.5 4.9 6.9 17.6 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 HSP20 PF00011.16 AAS50238.1 - 2.2e-18 65.9 0.1 2.9e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Peptidase_M1 PF01433.15 AAS50239.2 - 1.6e-144 481.8 0.8 2.3e-144 481.3 0.6 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 AAS50239.2 - 2.2e-91 306.4 2.2 7.5e-91 304.7 0.8 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 AAS50239.2 - 6.8e-21 74.6 0.2 1.5e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily RNase_H2-Ydr279 PF09468.5 AAS50241.2 - 3.5e-61 207.0 0.0 4.4e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) RNase_PH PF01138.16 AAS50242.1 - 9.2e-19 68.0 0.0 1.5e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AAS50242.1 - 5.6e-12 45.4 0.1 2.2e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 HAD_2 PF13419.1 AAS50243.1 - 3.5e-18 66.4 0.0 1.3e-17 64.6 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AAS50243.1 - 1.4e-08 34.3 0.2 2.4e-08 33.5 0.2 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 AAS50243.1 - 1.4e-08 35.3 0.1 3.5e-07 30.8 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sigma70_ner PF04546.8 AAS50243.1 - 0.33 10.5 6.8 2.9 7.4 5.3 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region RNA_pol_3_Rpc31 PF11705.3 AAS50243.1 - 0.52 10.2 24.9 0.94 9.3 17.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GCIP PF13324.1 AAS50243.1 - 9.7 5.3 7.5 17 4.5 5.2 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF155 PF02582.9 AAS50244.1 - 2.3e-46 157.8 0.3 3.8e-46 157.1 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 FAD_binding_1 PF00667.15 AAS50245.1 - 7.5e-71 238.0 0.0 1.1e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 AAS50245.1 - 6.3e-31 107.2 1.6 1.5e-30 106.1 1.1 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 AAS50245.1 - 1.8e-21 76.7 0.0 3.2e-20 72.7 0.0 2.7 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Spore_IV_A PF09547.5 AAS50245.1 - 5.4e-05 22.0 0.1 0.00011 21.0 0.0 1.5 2 0 0 2 2 2 1 Stage IV sporulation protein A (spore_IV_A) Flavodoxin_5 PF12724.2 AAS50245.1 - 0.0067 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain MAGE PF01454.14 AAS50246.1 - 8e-43 146.0 0.0 9.5e-43 145.8 0.0 1.1 1 0 0 1 1 1 1 MAGE family WD40 PF00400.27 AAS50247.1 - 1.1e-08 34.6 0.0 0.002 17.9 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat TBCA PF02970.11 AAS50248.1 - 1.9e-29 101.5 4.5 2.2e-29 101.3 3.1 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A Myosin_tail_1 PF01576.14 AAS50248.1 - 0.0031 15.3 1.6 0.0033 15.2 1.1 1.0 1 0 0 1 1 1 1 Myosin tail Troponin PF00992.15 AAS50248.1 - 0.013 15.5 1.7 0.017 15.1 1.1 1.1 1 0 0 1 1 1 0 Troponin MutS_III PF05192.13 AAS50248.1 - 0.016 15.0 0.2 0.017 14.9 0.1 1.1 1 0 0 1 1 1 0 MutS domain III Orthopox_A5L PF06193.6 AAS50248.1 - 0.054 13.4 2.2 0.067 13.1 1.5 1.3 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like PolC_DP2 PF03833.8 AAS50248.1 - 0.11 10.1 1.3 0.13 9.9 0.9 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Fzo_mitofusin PF04799.8 AAS50248.1 - 0.13 11.6 0.4 0.19 11.0 0.1 1.3 1 1 0 1 1 1 0 fzo-like conserved region IncA PF04156.9 AAS50248.1 - 0.24 10.9 1.2 0.27 10.8 0.9 1.2 1 0 0 1 1 1 0 IncA protein FliD_C PF07195.7 AAS50248.1 - 1.7 7.8 4.3 3.5 6.8 0.1 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus ATP_bind_1 PF03029.12 AAS50249.1 - 5.3e-77 258.5 0.0 6.5e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 AAS50249.1 - 0.0003 20.7 0.0 0.0011 18.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 AAS50249.1 - 0.00045 19.7 0.0 0.00087 18.8 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 AAS50249.1 - 0.00083 20.1 2.6 0.0014 19.4 0.0 2.5 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AAS50249.1 - 0.0035 17.6 0.0 0.54 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AAS50249.1 - 0.008 15.9 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 AAS50249.1 - 0.036 14.1 0.1 0.27 11.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AAS50249.1 - 0.042 13.7 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 AAS50249.1 - 0.043 12.5 0.0 0.087 11.5 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_16 PF13191.1 AAS50249.1 - 0.12 12.2 0.0 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 AAS50249.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 AAS50249.1 - 0.14 11.7 0.1 0.4 10.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SE PF00437.15 AAS50249.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MitMem_reg PF13012.1 AAS50250.1 - 5.3e-40 136.0 1.8 8.4e-40 135.4 0.4 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 AAS50250.1 - 2.2e-28 98.2 0.0 4.2e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UbiA PF01040.13 AAS50251.1 - 2.1e-23 82.8 14.3 3.7e-23 82.0 9.9 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family Hexapep PF00132.19 AAS50252.1 - 9.4e-05 21.7 6.1 0.08 12.4 0.4 3.5 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 AAS50252.1 - 0.00071 19.6 0.0 0.0014 18.7 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 AAS50252.1 - 0.0017 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Gb3_synth PF04572.7 AAS50252.1 - 0.089 12.4 0.3 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region Hexapep_2 PF14602.1 AAS50252.1 - 0.52 9.9 9.8 1.3 8.6 3.0 2.8 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase YL1 PF05764.8 AAS50252.1 - 0.59 9.6 4.1 0.26 10.8 0.8 1.8 2 0 0 2 2 2 0 YL1 nuclear protein Fucokinase PF07959.7 AAS50252.1 - 2.7 6.4 5.1 1.6 7.2 0.8 2.1 2 1 0 2 2 2 0 L-fucokinase AAA PF00004.24 AAS50253.1 - 9.3e-43 145.5 0.0 1.7e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AAS50253.1 - 1.7e-08 34.6 0.2 1.4e-05 25.2 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 AAS50253.1 - 1.1e-06 28.3 0.2 3.1e-05 23.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AAS50253.1 - 3.3e-05 23.8 0.0 8.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AAS50253.1 - 4.9e-05 23.4 0.0 0.0034 17.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 AAS50253.1 - 7.2e-05 21.9 0.0 0.00016 20.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AAS50253.1 - 0.00014 21.5 0.1 0.00029 20.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 AAS50253.1 - 0.00069 20.4 1.2 0.0019 18.9 0.1 2.2 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 AAS50253.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 AAS50253.1 - 0.0013 17.5 0.1 0.0023 16.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 AAS50253.1 - 0.0018 18.4 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 AAS50253.1 - 0.0042 16.2 0.1 0.0091 15.1 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 AAS50253.1 - 0.0044 16.4 0.1 0.0044 16.4 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 AAS50253.1 - 0.0049 15.9 1.5 0.032 13.3 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.1 AAS50253.1 - 0.0067 16.0 0.2 0.016 14.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AAS50253.1 - 0.0069 16.2 0.2 0.018 14.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 AAS50253.1 - 0.008 16.1 0.4 0.02 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AAS50253.1 - 0.0082 16.4 0.1 0.042 14.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 AAS50253.1 - 0.012 15.9 4.5 3.8 7.7 2.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 AAS50253.1 - 0.012 15.5 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 AAS50253.1 - 0.018 14.1 1.5 0.032 13.3 0.0 2.2 3 0 0 3 3 3 0 KaiC PhoH PF02562.11 AAS50253.1 - 0.018 14.2 0.1 0.044 13.0 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 AAS50253.1 - 0.028 13.8 3.0 0.046 13.1 0.3 2.4 2 1 1 3 3 2 0 AAA domain AAA_11 PF13086.1 AAS50253.1 - 0.04 13.5 0.9 0.49 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 AAS50253.1 - 0.062 12.7 0.2 0.27 10.6 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 AAS50253.1 - 0.073 11.9 0.1 0.14 11.0 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 AAS50253.1 - 0.075 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 AAS50253.1 - 0.081 12.7 0.2 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 AAS50253.1 - 0.09 12.4 0.1 0.32 10.6 0.0 1.9 1 1 1 2 2 2 0 NACHT domain Phage_GP20 PF06810.6 AAS50253.1 - 0.11 11.8 4.3 3.2 7.1 2.2 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 Fib_alpha PF08702.5 AAS50253.1 - 0.14 12.2 1.1 0.35 10.9 0.7 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family IncA PF04156.9 AAS50253.1 - 0.22 11.0 5.2 0.41 10.2 3.6 1.4 1 0 0 1 1 1 0 IncA protein HIT PF01230.18 AAS50254.1 - 1.2e-14 54.6 3.8 3.7e-14 53.0 2.6 1.9 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AAS50254.1 - 8.5e-14 51.7 9.5 9.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding zf-C2H2_2 PF12756.2 AAS50254.1 - 7.2e-05 22.8 3.3 0.0087 16.1 0.3 2.8 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 AAS50254.1 - 0.0041 16.8 3.4 0.88 9.3 0.3 2.6 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_4 PF13894.1 AAS50254.1 - 0.072 13.4 9.2 0.73 10.3 0.3 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AAS50254.1 - 0.16 12.3 5.3 14 6.2 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zf-Di19 PF05605.7 AAS50254.1 - 0.22 11.6 5.4 4.2 7.5 0.3 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 AAS50254.1 - 0.73 9.5 5.8 0.71 9.6 0.7 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FYVE PF01363.16 AAS50254.1 - 2.7 7.9 5.7 4.3 7.3 0.1 2.5 2 0 0 2 2 2 0 FYVE zinc finger EF-hand_1 PF00036.27 AAS50256.1 - 1.3e-27 92.9 17.0 2.1e-08 32.8 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 AAS50256.1 - 3.5e-25 87.9 12.7 9.1e-14 51.3 1.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AAS50256.1 - 3.9e-22 76.0 13.2 9.8e-08 31.2 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 AAS50256.1 - 1.1e-20 72.9 16.2 4.6e-11 42.1 0.6 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 AAS50256.1 - 3.8e-18 63.9 10.5 5.3e-06 25.5 0.1 4.3 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.2 AAS50256.1 - 8.5e-09 35.0 2.0 0.00023 20.8 0.1 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 AAS50256.1 - 4e-08 33.0 0.6 0.00011 22.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 AAS50256.1 - 0.004 17.1 1.1 0.26 11.3 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region VCBS PF13517.1 AAS50256.1 - 0.012 15.9 0.3 0.44 10.9 0.0 2.4 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MgtE_N PF03448.12 AAS50256.1 - 0.045 14.0 2.6 0.078 13.2 0.1 2.4 3 0 0 3 3 3 0 MgtE intracellular N domain Caleosin PF05042.8 AAS50256.1 - 0.058 12.9 0.5 0.38 10.2 0.0 2.4 2 2 1 3 3 3 0 Caleosin related protein FG-GAP PF01839.18 AAS50256.1 - 3 7.6 4.8 5.8 6.7 0.1 2.5 2 0 0 2 2 2 0 FG-GAP repeat Dockerin_1 PF00404.13 AAS50256.1 - 3.7 7.4 5.2 11 5.9 0.1 2.8 2 0 0 2 2 2 0 Dockerin type I repeat CAP_GLY PF01302.20 AAS50257.1 - 3.1e-21 74.8 1.3 5e-21 74.1 0.9 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF4201 PF13870.1 AAS50257.1 - 5.3 6.4 55.2 9.4 5.6 9.7 4.7 2 2 1 3 3 3 0 Domain of unknown function (DUF4201) Sec20 PF03908.8 AAS50257.1 - 7.7 6.2 17.8 10 5.9 2.0 4.2 3 0 0 3 3 3 0 Sec20 PIGA PF08288.7 AAS50258.1 - 1.1e-44 150.7 4.3 1.4e-44 150.3 1.3 2.4 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 AAS50258.1 - 1e-27 96.6 0.0 1.6e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AAS50258.1 - 8e-18 64.7 0.2 1.6e-17 63.8 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 AAS50258.1 - 8.6e-14 51.9 0.0 1.8e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 AAS50258.1 - 9.9e-11 41.9 0.0 2.3e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AAS50258.1 - 0.0031 17.7 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 AAS50258.1 - 0.027 13.9 0.7 0.5 9.8 0.0 2.6 2 1 1 3 3 3 0 Starch synthase catalytic domain Mec-17 PF05301.6 AAS50258.1 - 0.064 13.2 0.1 3.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Touch receptor neuron protein Mec-17 TFR_dimer PF04253.10 AAS50259.1 - 1.4e-25 89.3 0.1 2.5e-25 88.4 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 AAS50259.1 - 0.0026 17.4 0.0 0.0089 15.7 0.0 1.9 2 0 0 2 2 2 1 PA domain Cyt-b5 PF00173.23 AAS50260.1 - 5.1e-13 48.6 0.0 7e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TAP_C PF03943.8 AAS50262.1 - 3.8e-15 55.0 0.8 5.9e-14 51.2 0.0 2.5 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.2 AAS50262.1 - 2.1e-05 24.0 4.8 0.00014 21.3 1.1 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 AAS50262.1 - 4.6e-05 23.0 0.3 8.1e-05 22.2 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 AAS50262.1 - 0.04 13.9 1.0 13 6.2 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 AAS50262.1 - 0.44 10.9 3.0 11 6.7 0.0 4.0 3 0 0 3 3 3 0 Leucine rich repeat Sec63 PF02889.11 AAS50263.1 - 9.5e-17 61.1 0.0 7.3e-15 54.9 0.0 2.1 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 AAS50263.1 - 4.8e-16 58.2 0.3 1.1e-15 57.1 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Acetyltransf_1 PF00583.19 AAS50264.1 - 6.9e-11 42.0 0.1 9.6e-11 41.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 AAS50264.1 - 1e-08 35.3 0.0 1.2e-08 35.0 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AAS50264.1 - 1.2e-08 35.0 0.0 1.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AAS50264.1 - 1.2e-07 31.9 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 AAS50264.1 - 0.0026 17.3 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AAS50264.1 - 0.014 15.2 0.1 0.02 14.7 0.1 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 AAS50264.1 - 0.094 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4177 PF13783.1 AAS50265.1 - 0.013 15.0 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) DUF2962 PF11176.3 AAS50266.1 - 1.2e-51 174.2 8.3 1.5e-51 174.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) CENP-Q PF13094.1 AAS50266.1 - 2.4 8.1 12.8 3.7 7.5 8.9 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit OmpH PF03938.9 AAS50266.1 - 7.3 6.5 9.6 7.3 6.5 6.2 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DNA_pol_B PF00136.16 AAS50267.2 - 1.4e-90 304.3 0.0 2.1e-90 303.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 AAS50267.2 - 3.9e-22 78.5 0.0 2.7e-16 59.3 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 AAS50267.2 - 2.9e-12 46.3 9.2 6e-12 45.3 6.4 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Siah-Interact_N PF09032.6 AAS50268.1 - 0.048 13.7 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Siah interacting protein, N terminal SET PF00856.23 AAS50269.1 - 1.1e-09 38.8 0.1 2.6e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 SET domain zf-FCS PF06467.9 AAS50269.1 - 0.14 11.8 2.3 0.29 10.8 0.1 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Rhodanese PF00581.15 AAS50270.1 - 1.6e-19 70.2 0.0 2e-10 40.9 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Clp1 PF06807.9 AAS50271.1 - 2.2e-14 53.6 0.0 3.7e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 AAS50271.1 - 3.1e-06 26.9 0.0 6.3e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 AAS50271.1 - 0.00049 19.7 0.0 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 AAS50271.1 - 0.0016 18.4 0.0 0.0054 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 AAS50271.1 - 0.003 17.8 0.1 0.046 14.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 AAS50271.1 - 0.011 15.1 0.0 0.036 13.5 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 AAS50271.1 - 0.015 16.0 0.0 0.07 13.9 0.0 2.1 2 1 1 3 3 3 0 AAA domain Apc5 PF12862.2 AAS50272.1 - 1.4e-20 72.9 6.1 3.7e-20 71.5 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 5 YtxC PF08812.6 AAS50272.1 - 0.061 12.8 2.6 0.11 11.9 1.8 1.3 1 0 0 1 1 1 0 YtxC-like family CBM_25 PF03423.8 AAS50272.1 - 0.11 12.5 0.1 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) HATPase_c_3 PF13589.1 AAS50273.1 - 1e-08 34.9 0.0 1.8e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AAS50273.1 - 3.1e-08 33.3 0.0 5.4e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 AAS50273.1 - 2.9e-07 30.1 0.0 3.9e-06 26.5 0.0 2.3 1 1 1 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 AAS50273.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain Period_C PF12114.3 AAS50274.1 - 5.1 6.6 11.7 6.3 6.3 8.1 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Macoilin PF09726.4 AAS50274.1 - 9.9 4.3 7.7 10 4.2 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3661 PF12400.3 AAS50275.1 - 4.9e-44 149.5 2.5 8.4e-44 148.7 1.7 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein adh_short PF00106.20 AAS50277.1 - 8.2e-17 61.6 0.1 1.5e-15 57.5 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 AAS50277.1 - 2.6e-09 37.2 0.0 4.2e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AAS50277.1 - 4.1e-05 23.3 0.0 8.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AAS50277.1 - 0.016 14.6 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AAS50277.1 - 0.04 13.9 0.0 0.95 9.4 0.0 2.4 1 1 1 2 2 2 0 NADH(P)-binding tRNA-synt_1 PF00133.17 AAS50278.2 - 8e-44 149.6 0.0 1.1e-34 119.4 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 AAS50278.2 - 2.9e-21 75.6 0.8 7.4e-10 38.0 0.0 4.4 5 0 0 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 AAS50278.2 - 1.2e-10 41.3 0.0 4e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 AAS50278.2 - 7.2e-07 28.6 0.0 1.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Pet20 PF08692.5 AAS50279.1 - 1.5e-06 28.2 0.0 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial protein Pet20 DUF836 PF05768.9 AAS50280.1 - 2.4e-18 66.1 0.2 3.3e-18 65.7 0.2 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) ERM PF00769.14 AAS50281.2 - 0.0026 17.3 18.5 0.0026 17.3 12.8 5.3 1 1 4 6 6 6 2 Ezrin/radixin/moesin family PAP2 PF01569.16 AAS50282.1 - 5e-22 77.9 0.5 5e-22 77.9 0.4 1.8 2 1 0 2 2 2 1 PAP2 superfamily DsbB PF02600.11 AAS50282.1 - 0.014 15.1 3.2 0.19 11.5 0.0 2.4 3 0 0 3 3 3 0 Disulfide bond formation protein DsbB DUF3043 PF11241.3 AAS50282.1 - 0.27 10.8 1.0 0.52 9.8 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF4191 PF13829.1 AAS50282.1 - 0.67 9.0 3.3 0.69 8.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) HGTP_anticodon2 PF12745.2 AAS50283.1 - 3e-97 325.0 1.8 3e-97 325.0 1.3 2.5 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 AAS50283.1 - 2e-69 233.6 2.6 5.5e-44 150.2 0.0 4.5 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 AAS50283.1 - 1.1e-40 139.3 0.6 1.5e-21 76.6 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 AAS50283.1 - 2.1e-17 63.0 0.3 7.3e-17 61.2 0.2 2.0 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 AAS50283.1 - 1.4e-14 53.9 0.0 3.6e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Histidyl-tRNA synthetase APH PF01636.18 AAS50283.1 - 0.1 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Med20 PF08612.6 AAS50284.1 - 3.1e-51 173.6 0.1 3.5e-51 173.5 0.1 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Ribosomal_L30 PF00327.15 AAS50284.1 - 0.024 14.1 0.1 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e CTD_bind PF04818.8 AAS50285.1 - 1.4e-21 76.4 2.1 1.9e-21 76.0 0.7 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.3 AAS50285.1 - 0.00092 18.8 1.2 0.002 17.7 0.0 2.0 2 1 0 2 2 2 1 CTD kinase subunit gamma CTK3 AAA_13 PF13166.1 AAS50285.1 - 0.032 12.7 1.6 0.042 12.3 1.1 1.1 1 0 0 1 1 1 0 AAA domain RIX1 PF08167.7 AAS50285.1 - 0.038 13.6 0.1 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis ING PF12998.2 AAS50285.1 - 0.044 14.0 0.8 0.2 11.9 0.3 2.3 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DEAD PF00270.24 AAS50286.1 - 5.1e-23 81.3 0.0 9e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 AAS50286.1 - 5.5e-15 55.7 0.1 1.3e-14 54.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 AAS50286.1 - 1.2e-11 44.2 0.1 8e-11 41.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS50286.1 - 3.7e-06 26.8 0.0 6.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SRX PF09201.5 AAS50287.2 - 4.9e-52 175.5 0.3 9e-52 174.6 0.2 1.5 1 0 0 1 1 1 1 SRX SRP54 PF00448.17 AAS50287.2 - 7.7e-49 165.8 0.4 2.3e-46 157.7 0.3 2.4 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 AAS50287.2 - 1.1e-06 28.2 1.4 2.2e-06 27.2 0.6 1.7 2 0 0 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 AAS50287.2 - 2.2e-06 27.2 0.1 5.3e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 AAS50287.2 - 9.4e-06 25.6 0.0 3.5e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 AAS50287.2 - 0.00024 19.9 0.0 0.00082 18.2 0.0 1.9 1 1 0 1 1 1 1 ArgK protein AAA_22 PF13401.1 AAS50287.2 - 0.00079 19.5 0.1 0.006 16.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 AAS50287.2 - 0.0011 18.0 0.0 0.29 10.1 0.0 2.4 2 0 0 2 2 2 2 Anion-transporting ATPase cobW PF02492.14 AAS50287.2 - 0.0016 17.8 0.1 0.0031 16.9 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 AAS50287.2 - 0.0064 16.1 0.1 0.027 14.1 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_NifH PF00142.13 AAS50287.2 - 0.018 14.2 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.1 AAS50287.2 - 0.019 14.9 0.0 0.061 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 AAS50287.2 - 0.032 14.1 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 AAS50287.2 - 0.034 14.0 0.0 0.48 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Response_reg PF00072.19 AAS50287.2 - 0.064 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Response regulator receiver domain Cyt-b5 PF00173.23 AAS50288.1 - 2.3e-13 49.7 0.0 4.5e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 AAS50288.1 - 2e-07 30.7 10.6 2.1e-07 30.6 6.2 1.9 1 1 1 2 2 2 1 Fatty acid desaturase zf-HIT PF04438.11 AAS50289.1 - 2.4e-07 30.2 15.0 3.9e-07 29.5 10.4 1.4 1 0 0 1 1 1 1 HIT zinc finger Na_trans_assoc PF06512.8 AAS50289.1 - 0.26 11.2 3.4 0.5 10.3 2.4 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated CDC45 PF02724.9 AAS50289.1 - 0.64 7.9 2.2 0.84 7.5 1.5 1.1 1 0 0 1 1 1 0 CDC45-like protein V-ATPase_G PF03179.10 AAS50290.1 - 7.3e-31 106.5 12.6 8.2e-31 106.4 8.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.3 AAS50290.1 - 0.0015 17.7 7.7 0.0015 17.7 5.4 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) GA PF01468.12 AAS50290.1 - 0.0074 16.4 0.9 0.28 11.3 0.1 2.6 2 1 0 2 2 2 1 GA module MAP7 PF05672.6 AAS50290.1 - 0.052 12.9 15.5 0.064 12.6 10.8 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family FlgN PF05130.7 AAS50290.1 - 0.18 12.0 8.2 0.2 11.9 5.7 1.1 1 0 0 1 1 1 0 FlgN protein DUF2570 PF10828.3 AAS50290.1 - 0.44 10.1 7.5 0.38 10.3 2.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) ATP-synt_B PF00430.13 AAS50290.1 - 1.8 8.3 17.4 5.8 6.7 12.0 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) APG6 PF04111.7 AAS50290.1 - 2.9 6.8 6.6 3.3 6.6 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIVA PF05103.8 AAS50290.1 - 4.8 7.2 11.2 85 3.2 7.6 2.0 1 1 0 1 1 1 0 DivIVA protein Aldedh PF00171.17 AAS50291.1 - 9e-126 419.9 0.0 1.1e-125 419.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.14 AAS50292.1 - 4.7e-35 120.4 5.1 7.4e-35 119.8 3.5 1.3 1 0 0 1 1 1 1 Ribosome recycling factor Sec5 PF15469.1 AAS50292.1 - 0.005 16.5 1.0 0.009 15.7 0.7 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec5 Mitofilin PF09731.4 AAS50292.1 - 0.0054 15.4 5.7 0.0072 15.0 3.9 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Aminotran_1_2 PF00155.16 AAS50292.1 - 0.089 11.7 1.4 0.15 10.9 0.0 2.0 2 1 0 2 2 2 0 Aminotransferase class I and II DASH_Duo1 PF08651.5 AAS50292.1 - 0.13 11.8 1.7 0.38 10.3 1.2 1.8 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF922 PF06037.6 AAS50292.1 - 0.32 10.2 2.9 0.53 9.5 2.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) IncA PF04156.9 AAS50292.1 - 0.47 10.0 3.0 0.99 8.9 2.1 1.5 1 0 0 1 1 1 0 IncA protein GLTSCR1 PF15249.1 AAS50292.1 - 0.49 10.5 3.1 1.1 9.4 0.6 2.1 2 0 0 2 2 2 0 Glioma tumor suppressor candidate region DUF1451 PF07295.6 AAS50292.1 - 0.55 10.0 3.9 18 5.0 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1451) Apolipoprotein PF01442.13 AAS50292.1 - 1.6 8.1 9.9 0.35 10.3 3.5 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain TPP_enzyme_M PF00205.17 AAS50293.1 - 1.4e-34 118.7 0.0 1.1e-33 115.8 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 AAS50293.1 - 3.5e-34 117.7 0.1 6e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AAS50293.1 - 1.4e-13 50.6 0.0 3e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ADH_zinc_N PF00107.21 AAS50293.1 - 0.066 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RNB PF00773.14 AAS50294.1 - 2e-55 188.3 0.0 4.2e-55 187.2 0.0 1.5 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 AAS50294.1 - 0.0014 18.1 0.1 0.38 10.2 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease B OB domain DUF572 PF04502.8 AAS50294.1 - 0.0028 16.9 0.9 0.0065 15.7 0.6 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF572) Aldedh PF00171.17 AAS50295.1 - 2.9e-101 339.0 0.0 3.5e-101 338.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Brr6_like_C_C PF10104.4 AAS50296.2 - 7.1e-45 151.8 0.1 9.4e-45 151.4 0.1 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF2782 PF11191.3 AAS50296.2 - 0.32 10.9 0.1 0.32 10.9 0.1 2.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2782) HDA2-3 PF11496.3 AAS50297.1 - 6e-92 307.6 0.0 1.2e-91 306.6 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 FUSC PF04632.7 AAS50297.1 - 0.61 8.4 13.8 1.1 7.5 9.6 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family TBPIP PF07106.8 AAS50297.1 - 3.4 7.1 14.3 0.74 9.3 5.0 2.5 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CorA PF01544.13 AAS50297.1 - 9.1 5.2 15.0 17 4.3 8.9 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Herpes_UL25 PF01499.11 AAS50297.1 - 9.1 4.4 16.5 1.3 7.2 7.8 1.9 1 1 1 2 2 2 0 Herpesvirus UL25 family FadA PF09403.5 AAS50297.1 - 9.5 6.2 10.7 3.2 7.7 4.5 2.4 2 1 1 3 3 3 0 Adhesion protein FadA Sec23_trunk PF04811.10 AAS50298.2 - 3.4e-11 42.9 0.0 2.4e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 AAS50298.2 - 7.9e-05 23.0 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 AAS50298.2 - 0.00095 18.6 3.4 0.0018 17.7 2.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 AAS50298.2 - 0.0011 18.3 0.0 0.0035 16.7 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain DUF2689 PF10894.3 AAS50298.2 - 0.088 12.6 0.2 0.28 10.9 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) Mhr1 PF12829.2 AAS50299.1 - 8.5e-36 121.6 0.6 1.5e-35 120.8 0.4 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination FA_hydroxylase PF04116.8 AAS50300.1 - 1.8e-14 54.1 12.9 1.8e-14 54.1 8.9 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily OSCP PF00213.13 AAS50301.1 - 1.5e-40 138.8 1.2 1.8e-40 138.6 0.8 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit TRAUB PF08164.7 AAS50302.1 - 1e-27 96.0 4.4 1.4e-27 95.5 0.1 3.0 4 0 0 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 AAS50302.1 - 2.6e-27 95.5 1.5 2.6e-27 95.5 1.0 2.6 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor MatE PF01554.13 AAS50303.1 - 8.9e-43 145.7 33.5 9.6e-22 77.3 6.6 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 AAS50303.1 - 0.00021 21.1 5.6 0.00021 21.1 3.9 4.9 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain PIH1 PF08190.7 AAS50304.1 - 5.5e-24 85.2 0.0 1.2e-23 84.0 0.0 1.6 1 1 0 1 1 1 1 pre-RNA processing PIH1/Nop17 AA_kinase PF00696.23 AAS50305.1 - 1.5e-34 119.6 0.1 2.4e-34 118.9 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 AAS50305.1 - 1.9e-19 69.1 0.2 5.2e-19 67.7 0.1 1.8 1 0 0 1 1 1 1 PUA domain CPSF_A PF03178.10 AAS50306.1 - 7.2e-85 284.8 0.3 2.2e-84 283.3 0.1 2.0 2 0 0 2 2 2 1 CPSF A subunit region PIG-F PF06699.6 AAS50307.1 - 2.9e-44 151.3 18.0 1.9e-43 148.6 12.5 1.9 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F AIM24 PF01987.12 AAS50308.1 - 8.2e-10 38.5 0.0 1.8e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 Zn_clus PF00172.13 AAS50309.1 - 4.5e-08 32.8 7.2 4.5e-08 32.8 5.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.16 AAS50310.1 - 1.6e-43 148.6 0.0 1.8e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med6 PF04934.9 AAS50311.1 - 3.9e-56 188.4 0.0 4.7e-56 188.2 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component IGR PF09597.5 AAS50312.1 - 2.9e-27 94.3 0.1 4.4e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 IGR protein motif HIT PF01230.18 AAS50313.2 - 2.5e-24 85.6 0.1 3.6e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AAS50313.2 - 3.7e-05 23.9 0.1 5.3e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding F-box PF00646.28 AAS50314.1 - 0.019 14.6 0.1 1.1 9.0 0.2 3.1 3 1 0 3 3 3 0 F-box domain FNIP PF05725.7 AAS50314.1 - 0.087 12.7 0.3 0.46 10.4 0.0 2.5 4 0 0 4 4 4 0 FNIP Repeat F-box-like PF12937.2 AAS50314.1 - 0.088 12.5 2.5 0.099 12.3 0.8 1.9 2 0 0 2 2 2 0 F-box-like LRR_8 PF13855.1 AAS50314.1 - 0.32 10.7 1.9 1.7 8.4 0.8 2.6 3 1 0 3 3 3 0 Leucine rich repeat MIR PF02815.14 AAS50316.2 - 3.7e-23 82.0 0.2 5.3e-23 81.5 0.1 1.1 1 0 0 1 1 1 1 MIR domain PMT PF02366.13 AAS50316.2 - 5.3e-14 52.1 13.9 5.3e-14 52.1 9.7 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Ins145_P3_rec PF08709.6 AAS50316.2 - 0.06 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Med21 PF11221.3 AAS50317.1 - 5.3e-44 149.6 5.0 6.2e-44 149.4 3.5 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Katanin_con80 PF13925.1 AAS50317.1 - 0.011 15.4 0.4 0.038 13.7 0.1 1.8 2 0 0 2 2 2 0 con80 domain of Katanin Med9 PF07544.8 AAS50317.1 - 0.017 14.8 4.3 0.03 14.0 0.5 2.8 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TMCO5 PF14992.1 AAS50317.1 - 0.031 13.4 2.6 0.042 12.9 1.8 1.4 1 1 0 1 1 1 0 TMCO5 family Dynamin_N PF00350.18 AAS50317.1 - 0.073 12.8 2.7 0.073 12.8 0.6 1.6 1 1 1 2 2 2 0 Dynamin family DUF2559 PF10832.3 AAS50317.1 - 0.11 12.2 0.0 5 6.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2559) Tropomyosin PF00261.15 AAS50317.1 - 0.16 11.0 5.9 0.28 10.2 3.4 1.7 1 1 1 2 2 2 0 Tropomyosin KH_5 PF13184.1 AAS50317.1 - 0.22 11.3 2.5 0.85 9.4 1.7 2.1 2 1 0 2 2 2 0 NusA-like KH domain ING PF12998.2 AAS50317.1 - 0.52 10.6 3.9 1.8 8.8 0.7 2.2 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Sec34 PF04136.10 AAS50317.1 - 0.73 9.5 5.2 9.9 5.8 0.1 2.9 1 1 2 3 3 3 0 Sec34-like family Syntaxin_2 PF14523.1 AAS50317.1 - 0.76 9.8 4.6 1.6 8.7 1.2 2.2 1 1 1 2 2 2 0 Syntaxin-like protein DUF1492 PF07374.6 AAS50317.1 - 0.77 9.9 5.2 15 5.7 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1492) HalX PF08663.5 AAS50317.1 - 1 9.3 4.0 14 5.7 0.0 3.3 4 0 0 4 4 4 0 HalX domain IncA PF04156.9 AAS50317.1 - 7.5 6.1 8.6 50 3.3 6.0 2.1 1 1 0 1 1 1 0 IncA protein DUF4404 PF14357.1 AAS50317.1 - 9.8 6.6 7.5 4.1 7.8 0.8 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) Mito_fiss_reg PF05308.6 AAS50319.1 - 0.0081 15.5 0.0 0.43 9.9 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial fission regulator RNase_P_p30 PF01876.11 AAS50320.1 - 6.4e-42 142.3 0.0 8.8e-42 141.8 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 AP_endonuc_2 PF01261.19 AAS50320.1 - 0.058 12.6 0.7 0.16 11.2 0.4 2.0 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel zf-ZPR1 PF03367.8 AAS50321.1 - 0.093 11.8 0.4 0.24 10.5 0.3 1.6 1 0 0 1 1 1 0 ZPR1 zinc-finger domain PspB PF06667.7 AAS50321.1 - 7.9 6.4 7.2 5.1 7.1 0.1 3.2 2 1 1 3 3 3 0 Phage shock protein B ApbA PF02558.11 AAS50322.1 - 5.9e-33 113.4 0.0 8.1e-33 112.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 AAS50322.1 - 1.3e-28 99.4 0.0 2e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal HSP70 PF00012.15 AAS50323.2 - 5.5e-80 268.9 2.3 2e-78 263.8 0.7 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 AAS50323.2 - 6.5e-09 34.8 0.0 9.9e-09 34.2 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.3 AAS50323.2 - 0.0041 16.0 0.1 0.007 15.2 0.0 1.3 1 0 0 1 1 1 1 Type IV pilus assembly protein PilM; PEP-utilizers PF00391.18 AAS50323.2 - 0.095 12.2 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain BSD PF03909.12 AAS50324.1 - 4.2e-25 87.2 7.0 8.8e-14 51.0 0.4 2.9 3 0 0 3 3 3 2 BSD domain TFIIH_BTF_p62_N PF08567.6 AAS50324.1 - 1.3e-24 85.5 0.2 3e-24 84.4 0.1 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain MHC_II_beta PF00969.14 AAS50324.1 - 0.017 15.1 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain DEAD PF00270.24 AAS50325.2 - 1.1e-47 161.7 0.0 2.6e-47 160.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS50325.2 - 3.9e-27 93.9 0.0 9.1e-27 92.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS50325.2 - 1.2e-05 25.2 0.2 0.0001 22.2 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Brix PF04427.13 AAS50326.1 - 2.2e-60 203.6 0.3 3.2e-60 203.0 0.2 1.2 1 0 0 1 1 1 1 Brix domain DUF2514 PF10721.4 AAS50326.1 - 4.4 6.9 11.2 0.81 9.3 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) FYVE PF01363.16 AAS50327.1 - 1.5e-16 60.0 12.6 1.5e-16 60.0 8.8 2.9 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 AAS50327.1 - 3.5e-10 39.5 1.9 3.5e-10 39.5 1.3 4.0 3 2 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.1 AAS50327.1 - 0.00036 20.2 0.7 0.00036 20.2 0.5 3.1 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 AAS50327.1 - 0.0035 17.3 2.3 0.0035 17.3 1.6 4.6 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 AAS50327.1 - 0.92 9.4 16.1 3.6 7.5 9.3 2.8 2 1 0 2 2 2 0 FYVE-type zinc finger MaoC_dehydrat_N PF13452.1 AAS50328.1 - 0.00011 22.0 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.14 AAS50328.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 MaoC like domain Ins_P5_2-kin PF06090.7 AAS50329.1 - 3.4e-51 174.1 0.0 2e-50 171.6 0.0 1.8 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DS PF01916.12 AAS50330.1 - 5.8e-146 485.3 0.0 6.7e-146 485.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Methyltransf_23 PF13489.1 AAS50331.1 - 4.1e-15 55.8 0.0 8e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AAS50331.1 - 9.1e-12 45.3 0.0 3.4e-11 43.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AAS50331.1 - 2.8e-10 39.6 0.3 7.1e-05 22.0 0.0 2.8 2 1 1 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AAS50331.1 - 2.6e-09 37.4 0.0 1e-06 29.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AAS50331.1 - 2.5e-08 34.1 0.0 2.9e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS50331.1 - 7e-08 32.1 0.1 1.6e-06 27.8 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS50331.1 - 8.5e-08 32.7 0.0 3.3e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain BLYB PF05289.6 AAS50331.1 - 0.046 13.5 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein DUF4435 PF14491.1 AAS50331.1 - 0.058 13.2 2.5 0.13 12.0 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4435) N2227 PF07942.7 AAS50331.1 - 0.095 11.6 0.0 2.4 7.0 0.0 2.1 2 0 0 2 2 2 0 N2227-like protein RIC3 PF15361.1 AAS50331.1 - 0.098 12.8 0.7 0.19 11.9 0.5 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 ECR1_N PF14382.1 AAS50332.1 - 4.6e-13 48.2 0.5 1.6e-12 46.4 0.0 2.2 3 0 0 3 3 3 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 AAS50332.1 - 0.016 15.1 0.0 0.48 10.4 0.0 2.7 2 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 Dicistro_VP4 PF11492.3 AAS50332.1 - 0.13 12.3 0.0 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 Met_10 PF02475.11 AAS50333.1 - 1.8e-70 236.6 0.0 2.6e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 AAS50333.1 - 0.0082 16.1 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AAS50333.1 - 0.0086 15.4 0.0 0.28 10.5 0.0 2.6 2 1 1 3 3 3 1 Methyltransferase small domain Methyltransf_18 PF12847.2 AAS50333.1 - 0.011 16.2 0.0 0.03 14.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MethyltransfD12 PF02086.10 AAS50333.1 - 0.023 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Cyclin PF08613.6 AAS50334.1 - 1.5e-10 41.6 0.1 2e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AAS50334.1 - 5.9e-08 32.3 0.2 9.7e-08 31.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain TraE PF05309.6 AAS50334.1 - 0.084 12.0 0.1 10 5.2 0.0 2.1 2 0 0 2 2 2 0 TraE protein Adenylsucc_synt PF00709.16 AAS50335.1 - 0.036 12.7 4.9 0.042 12.5 3.3 1.2 1 1 0 1 1 1 0 Adenylosuccinate synthetase MRJP PF03022.11 AAS50335.1 - 0.1 11.7 2.4 0.13 11.4 1.6 1.1 1 0 0 1 1 1 0 Major royal jelly protein FTCD_C PF04961.7 AAS50335.1 - 0.54 9.6 4.7 0.42 10.0 2.3 1.5 1 1 0 1 1 1 0 Formiminotransferase-cyclodeaminase Nefa_Nip30_N PF10187.4 AAS50335.1 - 0.89 9.7 14.1 0.048 13.8 5.2 1.9 1 1 1 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DHC PF09626.5 AAS50335.1 - 2.9 8.5 6.9 0.79 10.3 1.4 2.0 1 1 1 2 2 2 0 Dihaem cytochrome c IncA PF04156.9 AAS50335.1 - 5.5 6.5 12.2 7 6.2 8.5 1.1 1 0 0 1 1 1 0 IncA protein SNF2_N PF00176.18 AAS50336.2 - 2.5e-47 161.1 0.5 6.5e-47 159.7 0.3 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 AAS50336.2 - 3.3e-10 39.6 14.2 9.8e-10 38.1 9.9 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AAS50336.2 - 1e-07 31.4 11.9 2.3e-07 30.3 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS50336.2 - 1.8e-07 31.0 16.0 5.4e-07 29.5 11.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AAS50336.2 - 6.4e-07 28.9 14.9 1.8e-06 27.4 10.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AAS50336.2 - 1.8e-06 27.9 6.6 1.8e-06 27.9 4.5 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 AAS50336.2 - 0.00013 21.6 14.4 0.00034 20.2 10.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.26 AAS50336.2 - 0.018 14.9 0.0 0.067 13.0 0.0 2.0 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 AAS50336.2 - 0.051 13.4 16.0 0.14 12.0 11.1 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 AAS50336.2 - 0.056 13.2 6.0 0.14 12.0 4.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 AAS50336.2 - 0.07 12.8 8.1 0.4 10.4 5.6 2.4 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 AAS50336.2 - 0.089 12.5 8.8 0.018 14.7 3.5 1.8 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Prp19 PF08606.6 AAS50336.2 - 0.11 12.1 5.4 4.2 7.1 0.0 3.0 3 0 0 3 3 2 0 Prp19/Pso4-like AMP-binding_C_2 PF14535.1 AAS50336.2 - 1 9.4 5.5 14 5.8 0.1 4.0 4 0 0 4 4 4 0 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 AAS50337.1 - 4.7e-59 199.6 0.0 6.7e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS50337.1 - 7e-23 81.0 0.0 8e-19 67.7 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AAS50337.1 - 0.0001 21.3 0.1 0.12 11.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 AAS50337.1 - 0.00079 18.5 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Myc_N PF01056.13 AAS50337.1 - 1.9 7.6 4.5 4.3 6.4 3.1 1.5 1 0 0 1 1 1 0 Myc amino-terminal region ABC_tran PF00005.22 AAS50338.2 - 2.5e-44 150.9 0.1 1.4e-22 80.4 0.0 4.3 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 AAS50338.2 - 1e-17 65.0 0.0 0.0021 18.0 0.0 4.5 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 AAS50338.2 - 1.1e-15 57.4 0.0 1.4e-06 27.7 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AAS50338.2 - 2.5e-10 41.0 0.6 0.00058 20.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 AAS50338.2 - 2.5e-09 36.5 0.0 0.0028 17.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 AAS50338.2 - 1e-08 35.4 0.0 0.00053 20.1 0.0 4.0 4 1 0 4 4 3 2 AAA domain DUF258 PF03193.11 AAS50338.2 - 1.7e-08 33.7 0.0 0.0001 21.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 AAS50338.2 - 5.7e-08 33.6 0.0 0.0071 17.1 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 AAS50338.2 - 2.4e-07 30.8 0.0 0.0038 17.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 AAS50338.2 - 5.1e-07 29.6 0.0 0.0055 16.6 0.0 3.2 3 1 0 3 3 3 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 AAS50338.2 - 5.9e-07 29.4 0.0 3.7e-05 23.5 0.0 2.9 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.1 AAS50338.2 - 2e-06 27.7 0.0 0.094 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 AAS50338.2 - 3.4e-06 27.2 0.1 0.62 10.2 0.0 4.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 AAS50338.2 - 3.7e-06 27.4 0.0 0.031 14.7 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein ArgK PF03308.11 AAS50338.2 - 4.7e-06 25.5 0.1 0.063 12.0 0.0 2.4 2 0 0 2 2 2 2 ArgK protein SbcCD_C PF13558.1 AAS50338.2 - 5.4e-06 26.2 0.0 0.0095 15.8 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 AAS50338.2 - 5.7e-06 25.9 0.0 0.28 10.5 0.0 3.5 4 0 0 4 4 4 2 AAA-like domain AAA_18 PF13238.1 AAS50338.2 - 1.1e-05 25.7 1.1 0.029 14.6 0.0 3.8 5 0 0 5 5 2 1 AAA domain RNA_helicase PF00910.17 AAS50338.2 - 1.1e-05 25.5 0.0 0.1 12.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase HEAT_2 PF13646.1 AAS50338.2 - 1.5e-05 25.2 0.7 0.0099 16.1 0.0 3.4 1 1 2 3 3 3 2 HEAT repeats AAA_16 PF13191.1 AAS50338.2 - 7e-05 22.8 0.6 0.22 11.5 0.0 4.1 5 0 0 5 5 4 1 AAA ATPase domain MobB PF03205.9 AAS50338.2 - 7.8e-05 22.3 0.0 0.38 10.4 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B MutS_V PF00488.16 AAS50338.2 - 0.00017 21.0 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 1 MutS domain V Vac14_Fab1_bd PF12755.2 AAS50338.2 - 0.00024 21.4 0.1 0.1 12.9 0.0 3.1 3 0 0 3 3 2 1 Vacuolar 14 Fab1-binding region Arch_ATPase PF01637.13 AAS50338.2 - 0.00031 20.5 0.0 0.55 9.8 0.0 3.1 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 AAS50338.2 - 0.0004 20.2 0.0 2.7 7.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 AAS50338.2 - 0.00043 20.1 0.6 0.33 10.7 0.0 4.0 4 1 0 4 4 4 1 Domain of unknown function DUF87 NACHT PF05729.7 AAS50338.2 - 0.00053 19.6 0.0 0.49 10.0 0.0 2.8 3 0 0 3 3 2 1 NACHT domain PduV-EutP PF10662.4 AAS50338.2 - 0.00064 19.2 0.0 0.2 11.1 0.0 3.1 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.1 AAS50338.2 - 0.00085 17.9 2.9 2.3 6.5 0.0 4.0 3 1 0 4 4 4 2 AAA domain cobW PF02492.14 AAS50338.2 - 0.0014 18.0 0.2 1.2 8.5 0.0 3.3 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 AAS50338.2 - 0.0016 18.0 0.0 3.6 7.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain DUF3385 PF11865.3 AAS50338.2 - 0.008 16.1 1.0 0.8 9.6 0.3 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3385) ParcG PF10274.4 AAS50338.2 - 0.008 16.0 0.7 3.1 7.6 0.0 3.0 2 1 1 3 3 3 1 Parkin co-regulated protein UME PF08064.8 AAS50338.2 - 0.01 15.7 0.6 0.038 13.9 0.2 2.0 1 1 0 1 1 1 0 UME (NUC010) domain HEAT_EZ PF13513.1 AAS50338.2 - 0.012 16.0 3.3 4.9 7.7 0.0 4.8 4 1 1 5 5 5 0 HEAT-like repeat Zeta_toxin PF06414.7 AAS50338.2 - 0.016 14.2 0.4 3 6.8 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin Mg_chelatase PF01078.16 AAS50338.2 - 0.017 14.3 0.1 1 8.4 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 AAS50338.2 - 0.019 13.8 0.1 0.48 9.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein HEAT PF02985.17 AAS50338.2 - 0.032 14.2 0.7 34 4.8 0.0 4.4 4 0 0 4 4 3 0 HEAT repeat Septin PF00735.13 AAS50338.2 - 0.043 12.8 0.2 1.3 8.0 0.0 2.6 3 0 0 3 3 3 0 Septin IstB_IS21 PF01695.12 AAS50338.2 - 0.053 12.9 0.1 12 5.2 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 AAS50338.2 - 0.056 12.9 0.3 2.9 7.2 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_19 PF13245.1 AAS50338.2 - 0.067 12.9 0.1 5.8 6.7 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain NTPase_1 PF03266.10 AAS50338.2 - 0.071 12.8 0.1 17 5.0 0.0 2.8 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.12 AAS50338.2 - 0.095 12.2 1.8 8.4 5.8 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein PLA2_B PF01735.13 AAS50339.2 - 5.3e-100 334.9 3.5 2.6e-84 283.1 0.2 2.1 2 0 0 2 2 2 2 Lysophospholipase catalytic domain Beta_elim_lyase PF01212.16 AAS50340.1 - 0.1 11.6 4.0 0.19 10.8 2.8 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Med15 PF09606.5 AAS50340.1 - 0.16 10.1 4.1 0.22 9.6 2.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SelP_N PF04592.9 AAS50340.1 - 0.34 10.2 6.3 0.71 9.1 4.4 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region EF-hand_6 PF13405.1 AAS50341.1 - 1.4e-07 30.7 0.3 0.0043 16.8 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 AAS50341.1 - 2.6e-06 27.4 4.4 6.9e-06 26.1 0.6 3.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AAS50341.1 - 6e-06 25.1 1.1 0.12 11.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 AAS50341.1 - 9.6e-05 21.9 0.4 0.091 12.3 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 AAS50341.1 - 0.0012 18.1 0.3 0.014 14.7 0.0 2.5 2 0 0 2 2 2 1 EF hand UPF0052 PF01933.13 AAS50342.1 - 2.6e-57 194.4 0.0 4.1e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 HAD PF12710.2 AAS50343.2 - 3.4e-20 73.0 0.0 4.4e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 AAS50343.2 - 2.4e-06 26.9 0.0 5.3e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.7 AAS50343.2 - 1.4e-05 24.5 0.0 3.4e-05 23.2 0.0 1.5 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 AAS50343.2 - 3.9e-05 23.9 0.0 0.00024 21.3 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AAS50343.2 - 0.00081 19.8 0.0 0.046 14.1 0.0 2.4 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Iso_dh PF00180.15 AAS50344.1 - 1.3e-70 238.1 0.0 1.5e-70 237.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ALS_ss_C PF10369.4 AAS50345.1 - 2.2e-20 72.1 0.0 6.2e-20 70.6 0.0 1.8 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 AAS50345.1 - 2.5e-11 42.8 0.0 5.5e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 AAS50345.1 - 2.4e-08 33.6 0.0 4.9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 AAS50345.1 - 0.13 12.6 0.1 0.66 10.3 0.0 2.1 2 0 0 2 2 2 0 ACT domain Ribosomal_L27 PF01016.14 AAS50346.1 - 6.6e-31 105.9 0.1 1.4e-30 104.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal L27 protein TINF2_N PF14973.1 AAS50346.1 - 0.015 15.4 0.2 0.03 14.4 0.1 1.4 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus T2SF PF00482.18 AAS50346.1 - 0.098 12.5 0.6 0.39 10.6 0.1 2.1 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F DUF1325 PF07039.6 AAS50347.1 - 1.6e-35 121.5 0.0 2e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.7 AAS50347.1 - 0.0016 18.5 0.0 0.68 10.1 0.0 2.6 3 0 0 3 3 3 2 Agenet domain DUF4537 PF15057.1 AAS50347.1 - 0.0074 16.0 0.0 0.025 14.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) RRM_1 PF00076.17 AAS50348.1 - 2.5e-53 177.5 0.0 1.4e-19 69.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS50348.1 - 9.9e-29 99.1 0.0 2.9e-11 43.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS50348.1 - 1.6e-09 37.4 0.0 8.4e-05 22.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2015 PF09435.5 AAS50349.1 - 3.5e-32 110.8 1.3 1.5e-30 105.5 0.1 2.0 1 1 1 2 2 2 2 Fungal protein of unknown function (DUF2015) DUF3507 PF12015.3 AAS50350.1 - 1.2e-66 223.6 0.0 2.6e-66 222.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DUF2036 PF09724.4 AAS50351.1 - 8.2e-87 291.3 0.0 9.4e-87 291.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Mito_carr PF00153.22 AAS50352.1 - 2.9e-54 180.7 4.6 2e-19 69.1 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein COG5 PF10392.4 AAS50352.1 - 0.022 14.7 0.4 0.034 14.0 0.3 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 CALCOCO1 PF07888.6 AAS50352.1 - 0.026 12.8 0.0 0.034 12.4 0.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Aminotran_5 PF00266.14 AAS50353.1 - 4.1e-102 341.6 0.0 5e-102 341.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AAS50353.1 - 1.4e-10 40.8 0.0 2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 AAS50353.1 - 2e-08 33.7 0.0 5.1e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 AAS50353.1 - 0.0018 16.8 0.0 0.0027 16.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 AAS50353.1 - 0.025 12.8 0.0 0.038 12.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Iso_dh PF00180.15 AAS50354.1 - 7.9e-129 429.5 0.0 9e-129 429.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_L30 PF00327.15 AAS50355.1 - 4.6e-14 51.7 0.1 8.6e-14 50.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e RFX_DNA_binding PF02257.10 AAS50356.1 - 1.9e-32 111.2 0.0 4.7e-32 109.9 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.11 AAS50356.1 - 0.0067 16.6 0.0 0.024 14.8 0.0 1.9 1 0 0 1 1 1 1 Poxvirus D5 protein-like Pyrophosphatase PF00719.14 AAS50356.1 - 0.48 9.8 4.0 0.39 10.1 0.2 2.4 3 0 0 3 3 3 0 Inorganic pyrophosphatase WD40 PF00400.27 AAS50357.1 - 1.4e-47 157.9 17.8 3.6e-12 45.6 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 AAS50357.1 - 9.9e-11 40.4 12.9 0.0019 16.4 0.6 4.9 2 1 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AAS50357.1 - 2.9e-05 23.0 1.2 0.17 10.6 0.1 3.5 1 1 2 3 3 3 2 Nup133 N terminal like DUF3312 PF11768.3 AAS50357.1 - 0.00071 17.9 0.0 0.0036 15.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Coatomer_WDAD PF04053.9 AAS50357.1 - 0.023 13.4 0.1 0.063 12.0 0.0 1.5 1 1 0 2 2 2 0 Coatomer WD associated region CTDII PF01556.13 AAS50358.1 - 4.2e-26 90.6 0.9 7.1e-22 77.1 0.0 2.6 2 1 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 AAS50358.1 - 1.6e-24 85.3 0.4 2.6e-24 84.7 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain Malate_DH PF12434.3 AAS50358.1 - 0.37 10.5 3.1 2.1 8.0 2.1 2.3 1 1 0 1 1 1 0 Malate dehydrogenase enzyme DKCLD PF08068.7 AAS50359.1 - 1e-29 102.1 0.1 4.2e-29 100.2 0.1 2.1 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 AAS50359.1 - 1.1e-20 74.3 8.8 8e-20 71.5 0.0 4.0 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 AAS50359.1 - 4e-20 71.3 1.3 8.2e-20 70.3 0.9 1.6 1 0 0 1 1 1 1 PUA domain GAGA_bind PF06217.7 AAS50359.1 - 0.65 9.9 19.5 0.9 9.4 13.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.6 AAS50359.1 - 2.7 7.6 53.9 5.3 6.6 37.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF1510 PF07423.6 AAS50359.1 - 7.6 5.8 34.3 11 5.3 23.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) UEV PF05743.8 AAS50360.1 - 2e-30 104.9 0.0 5.8e-30 103.4 0.0 1.8 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.5 AAS50360.1 - 3.2e-26 90.7 0.1 1.4e-25 88.6 0.1 2.1 2 0 0 2 2 2 1 Vps23 core domain Sds3 PF08598.6 AAS50360.1 - 0.0064 16.0 0.4 0.014 14.9 0.3 1.5 1 0 0 1 1 1 1 Sds3-like ATP_synt_H PF05493.8 AAS50361.1 - 1.3e-21 76.3 4.4 1.5e-21 76.2 3.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit H MgtE PF01769.11 AAS50361.1 - 0.0084 16.3 1.4 0.009 16.2 1.0 1.0 1 0 0 1 1 1 1 Divalent cation transporter Na_Ca_ex PF01699.19 AAS50361.1 - 0.021 14.4 0.5 0.024 14.2 0.4 1.2 1 0 0 1 1 1 0 Sodium/calcium exchanger protein Cyt_c_ox_IV PF12270.3 AAS50361.1 - 0.033 13.9 0.6 0.034 13.8 0.4 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV AzlD PF05437.7 AAS50361.1 - 0.044 13.7 4.3 0.049 13.5 0.1 2.1 1 1 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DUF2142 PF09913.4 AAS50361.1 - 0.095 11.3 2.0 0.094 11.3 1.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) GWT1 PF06423.7 AAS50361.1 - 0.097 12.7 1.5 0.13 12.4 1.0 1.2 1 0 0 1 1 1 0 GWT1 7TM-7TMR_HD PF07698.6 AAS50361.1 - 0.13 11.6 3.3 0.15 11.5 2.3 1.0 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase DUF3624 PF12292.3 AAS50361.1 - 0.65 10.4 3.7 1.2 9.6 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3624) PLDc_2 PF13091.1 AAS50363.1 - 6.9e-17 61.3 0.0 1e-07 31.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 AAS50363.1 - 1.3e-11 43.8 1.4 1.5e-05 24.6 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Rer1 PF03248.8 AAS50364.1 - 6e-75 250.6 9.8 6.9e-75 250.5 6.8 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.4 AAS50364.1 - 2.4 7.3 6.1 0.71 9.0 0.8 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) eRF1_2 PF03464.10 AAS50365.1 - 2.7e-30 105.3 0.2 4.3e-30 104.7 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 AAS50365.1 - 7.4e-26 90.6 0.0 1.4e-24 86.5 0.0 2.5 2 1 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.10 AAS50365.1 - 3.8e-10 39.4 0.1 6.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 SNF2_N PF00176.18 AAS50365.1 - 0.021 13.6 0.4 0.05 12.4 0.3 1.6 1 1 0 1 1 1 0 SNF2 family N-terminal domain Septin PF00735.13 AAS50366.1 - 3.6e-107 357.5 2.1 4.2e-107 357.3 1.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 AAS50366.1 - 1e-09 38.3 0.2 1.6e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AAS50366.1 - 6.2e-08 32.2 0.7 1.9e-06 27.4 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 AAS50366.1 - 1.2e-06 27.8 0.6 3.5e-06 26.2 0.4 1.8 1 1 0 1 1 1 1 AIG1 family DUF258 PF03193.11 AAS50366.1 - 2.1e-06 27.0 0.0 3.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 AAS50366.1 - 6e-06 26.1 1.7 0.0064 16.3 0.4 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 AAS50366.1 - 0.00082 19.8 0.8 0.0021 18.5 0.2 1.9 1 1 1 2 2 2 1 Miro-like protein AAA_16 PF13191.1 AAS50366.1 - 0.00096 19.1 0.1 0.0035 17.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 AAS50366.1 - 0.0015 18.4 0.3 0.033 14.0 0.6 2.8 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 AAS50366.1 - 0.0019 17.7 0.0 0.0028 17.1 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 AAS50366.1 - 0.0024 18.1 0.9 0.0056 16.9 0.7 1.7 1 1 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.13 AAS50366.1 - 0.0054 16.2 0.1 0.014 14.9 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 AAS50366.1 - 0.0061 16.9 0.2 0.013 15.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 AAS50366.1 - 0.01 15.4 0.3 0.019 14.5 0.2 1.6 1 1 0 1 1 1 0 AAA domain IIGP PF05049.8 AAS50366.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.1 AAS50366.1 - 0.014 15.5 0.0 0.039 14.0 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 AAS50366.1 - 0.016 14.7 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 AAS50366.1 - 0.024 14.3 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 AAS50366.1 - 0.035 13.5 0.0 0.074 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AAS50366.1 - 0.045 13.6 0.1 0.14 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 AAS50366.1 - 0.046 13.1 0.1 0.92 8.9 0.0 2.7 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 AAS50366.1 - 0.048 12.5 0.4 0.081 11.7 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 AAS50366.1 - 0.081 13.1 0.0 0.2 11.8 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_17 PF13207.1 AAS50366.1 - 0.13 13.0 0.3 0.31 11.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain Ribosomal_L32p PF01783.18 AAS50367.2 - 3.3e-09 36.7 3.3 6.6e-09 35.8 2.3 1.5 1 0 0 1 1 1 1 Ribosomal L32p protein family CpXC PF14353.1 AAS50367.2 - 0.011 15.6 0.4 0.016 15.1 0.3 1.2 1 0 0 1 1 1 0 CpXC protein RecR PF02132.10 AAS50367.2 - 0.14 11.5 0.2 0.29 10.6 0.1 1.5 1 0 0 1 1 1 0 RecR protein TF_Zn_Ribbon PF08271.7 AAS50367.2 - 0.37 10.1 2.0 0.67 9.3 1.4 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Cupin_8 PF13621.1 AAS50368.1 - 1e-11 44.8 0.0 2.4e-11 43.6 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 AAS50368.1 - 5.3e-09 36.3 0.1 1.6e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 AAS50368.1 - 6.7e-07 28.9 0.0 1.9e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.6 AAS50368.1 - 0.00058 20.2 1.3 0.0015 18.8 0.0 2.3 2 1 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A GPI PF06560.6 AAS50368.1 - 0.065 12.2 0.1 0.14 11.1 0.1 1.5 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_2 PF07883.6 AAS50368.1 - 0.14 11.6 0.0 0.45 10.0 0.0 1.7 2 0 0 2 2 2 0 Cupin domain Citrate_synt PF00285.16 AAS50369.1 - 7.5e-100 334.1 0.0 9e-100 333.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase SH3BGR PF04908.10 AAS50371.2 - 0.0014 18.5 0.0 0.0041 17.0 0.0 1.9 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glycogen_syn PF05693.8 AAS50373.2 - 0 1089.1 0.0 0 1088.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 AAS50373.2 - 5.4e-09 35.7 0.0 6.5e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 AAS50373.2 - 1.2e-05 25.5 0.1 2.6e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 AAS50373.2 - 3.2e-05 23.5 0.3 6.7e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Pkinase PF00069.20 AAS50374.1 - 1.5e-72 243.8 0.0 2.3e-72 243.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS50374.1 - 4.5e-42 143.9 0.0 6.8e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS50374.1 - 0.001 18.1 0.0 0.0037 16.2 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 AAS50374.1 - 0.0087 15.1 0.0 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 AAS50374.1 - 0.045 12.5 0.0 0.079 11.7 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PACT_coil_coil PF10495.4 AAS50374.1 - 0.074 12.9 2.2 2.2 8.2 0.0 3.1 3 0 0 3 3 3 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein YrbL-PhoP_reg PF10707.4 AAS50374.1 - 0.15 11.4 0.0 0.15 11.4 0.0 2.0 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL bZIP_2 PF07716.10 AAS50375.1 - 3.9e-07 29.7 8.2 3.9e-07 29.7 5.7 3.5 2 1 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 AAS50375.1 - 0.00096 19.0 9.6 0.00096 19.0 6.6 2.2 2 1 0 2 2 2 1 bZIP transcription factor Herpes_UL6 PF01763.11 AAS50375.1 - 0.37 8.8 3.8 0.53 8.4 2.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Proteasome PF00227.21 AAS50377.1 - 8.2e-56 188.2 0.0 1.1e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AAS50377.1 - 1.3e-12 46.8 0.9 1.6e-12 46.5 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Helicase_C_3 PF13625.1 AAS50377.1 - 0.059 13.1 0.1 0.89 9.3 0.0 2.5 3 0 0 3 3 3 0 Helicase conserved C-terminal domain 7kD_coat PF02495.12 AAS50377.1 - 0.11 11.9 0.2 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 7kD viral coat protein TOM13 PF08219.6 AAS50378.2 - 7.9e-28 96.0 0.0 1.1e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 Motilin_ghrelin PF04644.7 AAS50378.2 - 0.48 10.2 3.7 0.81 9.5 0.3 2.2 2 0 0 2 2 2 0 Motilin/ghrelin Rpr2 PF04032.11 AAS50379.1 - 1e-16 60.5 0.2 1.4e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF3488 PF11992.3 AAS50380.1 - 0.11 11.0 5.4 0.21 10.1 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) LETM1 PF07766.8 AAS50381.1 - 5e-109 363.4 3.2 6.9e-109 363.0 2.2 1.2 1 0 0 1 1 1 1 LETM1-like protein YycC PF14174.1 AAS50381.1 - 0.0041 16.7 0.1 0.017 14.7 0.1 2.1 1 0 0 1 1 1 1 YycC-like protein Cellulase PF00150.13 AAS50382.1 - 6.6e-12 45.2 0.0 2.8e-09 36.5 0.0 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 AAS50382.1 - 0.0061 15.9 0.1 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 DNA_primase_S PF01896.14 AAS50383.1 - 5.3e-55 185.2 0.2 9.5e-55 184.3 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Proteasome PF00227.21 AAS50384.1 - 2.8e-41 140.8 0.0 3.3e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit HA2 PF04408.18 AAS50385.2 - 3e-28 97.8 0.0 7.6e-28 96.5 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AAS50385.2 - 3.7e-26 91.1 0.0 8.1e-26 90.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.18 AAS50385.2 - 2.6e-14 53.0 0.0 5e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.26 AAS50385.2 - 2.2e-12 46.6 0.0 1e-11 44.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 AAS50385.2 - 3e-06 26.8 0.2 9e-06 25.2 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AAS50385.2 - 2.1e-05 24.7 0.0 9.8e-05 22.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 AAS50385.2 - 0.0003 19.7 0.1 0.0023 16.8 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 AAS50385.2 - 0.0064 16.1 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 AAS50385.2 - 0.0081 15.0 0.0 0.051 12.4 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.1 AAS50385.2 - 0.014 15.2 0.1 0.2 11.5 0.1 2.7 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 AAS50385.2 - 0.015 15.5 3.2 0.59 10.4 0.0 3.5 3 0 0 3 3 3 0 ABC transporter AAA PF00004.24 AAS50385.2 - 0.038 14.1 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 AAS50385.2 - 0.043 13.2 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 AAS50385.2 - 0.052 13.0 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family PWI PF01480.12 AAS50385.2 - 0.092 12.8 1.3 9.8 6.3 0.4 2.8 2 0 0 2 2 2 0 PWI domain NAD_binding_8 PF13450.1 AAS50386.2 - 2e-08 34.1 0.0 6.4e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AAS50386.2 - 1.8e-05 23.8 0.0 5.6e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AAS50386.2 - 0.0012 19.1 0.0 0.03 14.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AAS50386.2 - 0.0061 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AAS50386.2 - 0.012 14.7 0.1 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 AAS50386.2 - 0.049 12.4 0.0 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 AAS50386.2 - 0.086 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Mqo PF06039.10 AAS50386.2 - 0.16 10.0 0.0 0.37 8.9 0.0 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.14 AAS50386.2 - 0.16 10.9 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain RRM_5 PF13893.1 AAS50387.1 - 1.6e-12 47.0 0.0 2.2e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS50387.1 - 3e-07 30.3 0.0 5e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AAS50387.1 - 3.3e-07 29.8 0.0 5.6e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GCR1_C PF12550.3 AAS50388.1 - 1.3e-17 63.4 1.4 1.3e-17 63.4 1.0 1.8 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes EB1 PF03271.12 AAS50389.1 - 2.1e-18 66.0 0.4 4.5e-18 65.0 0.2 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 AAS50389.1 - 3.5e-05 23.7 0.1 7.1e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain SlyX PF04102.7 AAS50389.1 - 0.16 12.3 1.0 0.37 11.1 0.7 1.6 1 0 0 1 1 1 0 SlyX Peptidase_M41 PF01434.13 AAS50390.2 - 2e-75 252.9 0.1 2.9e-75 252.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AAS50390.2 - 2.5e-43 147.4 0.0 5e-43 146.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 AAS50390.2 - 6.1e-06 26.3 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 AAS50390.2 - 0.00038 21.2 0.0 0.0016 19.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AAS50390.2 - 0.0019 18.3 0.2 0.13 12.4 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AAS50390.2 - 0.0023 17.6 0.7 0.008 15.9 0.5 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 AAS50390.2 - 0.0033 17.1 0.1 0.019 14.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 AAS50390.2 - 0.0043 15.8 0.1 0.0073 15.0 0.1 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 AAS50390.2 - 0.0047 16.3 0.1 0.014 14.8 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 AAS50390.2 - 0.0072 16.3 0.1 0.03 14.3 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 AAS50390.2 - 0.011 14.7 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 AAS50390.2 - 0.016 14.6 0.8 0.044 13.1 0.2 2.0 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 AAS50390.2 - 0.024 13.7 0.0 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_2 PF07724.9 AAS50390.2 - 0.066 13.1 0.1 0.36 10.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 AAS50390.2 - 0.066 13.5 0.2 0.2 11.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 AAS50390.2 - 0.11 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain HMG_box PF00505.14 AAS50391.2 - 1.3e-13 51.0 5.5 1.9e-12 47.2 3.8 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AAS50391.2 - 1.5e-05 25.2 0.8 3.1e-05 24.2 0.6 1.5 1 0 0 1 1 1 1 HMG-box domain Ribosomal_S5 PF00333.15 AAS50392.2 - 9.3e-24 82.9 0.3 1.6e-23 82.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 AAS50392.2 - 4.9e-19 67.3 0.0 1.2e-18 66.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain SURF1 PF02104.10 AAS50393.1 - 1.5e-66 224.2 0.6 2e-66 223.8 0.4 1.2 1 0 0 1 1 1 1 SURF1 family DUF3317 PF11779.3 AAS50393.1 - 0.097 12.1 1.8 0.17 11.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) DASH_Dam1 PF08653.5 AAS50394.2 - 4.4e-29 100.0 0.7 8e-29 99.1 0.5 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 IFP_35_N PF07334.8 AAS50394.2 - 0.048 13.6 0.7 0.11 12.4 0.5 1.6 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Ctr PF04145.10 AAS50395.1 - 1.2e-26 93.5 0.6 2.3e-26 92.5 0.4 1.5 1 0 0 1 1 1 1 Ctr copper transporter family SH2_2 PF14633.1 AAS50396.2 - 3e-102 340.3 3.5 1.1e-101 338.5 2.4 2.1 1 0 0 1 1 1 1 SH2 domain YqgF PF14639.1 AAS50396.2 - 8.2e-60 200.7 0.7 5.9e-59 197.9 0.0 2.5 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 AAS50396.2 - 3.3e-48 162.5 4.4 3.3e-48 162.5 3.0 4.0 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 AAS50396.2 - 1.6e-41 140.5 0.5 6.5e-41 138.6 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HTH_44 PF14641.1 AAS50396.2 - 1.9e-33 115.0 2.8 1.9e-33 115.0 1.9 3.1 4 0 0 4 4 4 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 AAS50396.2 - 1.2e-21 76.6 21.4 1.2e-21 76.6 14.9 5.4 4 1 2 6 6 6 1 Acidic N-terminal SPT6 SH2 PF00017.19 AAS50396.2 - 5.3e-11 42.1 0.0 1.7e-10 40.5 0.0 2.0 1 0 0 1 1 1 1 SH2 domain Formyl_trans_N PF00551.14 AAS50396.2 - 0.075 12.5 0.6 0.22 11.0 0.1 1.9 2 0 0 2 2 2 0 Formyl transferase RGS PF00615.14 AAS50396.2 - 0.21 11.6 10.9 0.038 14.0 1.8 3.6 3 0 0 3 3 3 0 Regulator of G protein signaling domain LETM1 PF07766.8 AAS50397.2 - 2.2e-103 344.9 4.6 2.2e-103 344.9 3.2 1.4 2 0 0 2 2 2 1 LETM1-like protein LexA_DNA_bind PF01726.11 AAS50397.2 - 0.0093 15.5 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 LexA DNA binding domain ACOX PF01756.14 AAS50397.2 - 0.022 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA oxidase RNA_pol_3_Rpc31 PF11705.3 AAS50397.2 - 0.3 10.9 6.4 2.2 8.1 0.4 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Aldo_ket_red PF00248.16 AAS50398.1 - 3.8e-41 140.7 0.0 4.5e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family tRNA-synt_1 PF00133.17 AAS50399.1 - 3.2e-228 758.6 0.0 2e-227 755.9 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AAS50399.1 - 1.5e-33 115.6 1.3 1.5e-33 115.6 0.9 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AAS50399.1 - 5.9e-17 61.4 0.1 8.4e-09 34.5 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 AAS50399.1 - 3.2e-09 36.3 14.2 1.6e-07 30.8 0.0 4.2 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Lzipper-MIP1 PF14389.1 AAS50399.1 - 0.00043 20.3 1.9 0.0014 18.7 1.3 1.8 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Val_tRNA-synt_C PF10458.4 AAS50399.1 - 0.0069 16.4 5.6 0.0069 16.4 3.9 3.4 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm Adenine_glyco PF03352.8 AAS50399.1 - 0.15 11.5 7.2 0.21 11.1 3.1 2.3 2 0 0 2 2 2 0 Methyladenine glycosylase AAA_23 PF13476.1 AAS50399.1 - 2.2 8.5 17.4 0.41 10.9 0.8 2.8 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 AAS50399.1 - 6.3 6.3 11.1 0.1 12.2 0.8 2.3 2 0 0 2 2 2 0 IncA protein RNase_PH PF01138.16 AAS50400.2 - 4.5e-16 59.3 0.0 8.1e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AAS50400.2 - 0.00058 19.7 0.1 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mito_carr PF00153.22 AAS50401.1 - 9.5e-56 185.5 2.4 3e-22 78.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CDP-OH_P_transf PF01066.16 AAS50402.1 - 5.1e-19 68.4 2.5 5.1e-19 68.4 1.8 1.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase AA_permease PF00324.16 AAS50403.2 - 2e-118 395.8 32.2 2.2e-118 395.6 22.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS50403.2 - 3.3e-20 72.0 32.0 4.4e-20 71.6 22.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1712 PF08217.6 AAS50405.1 - 6.8e-218 724.7 0.0 7.9e-218 724.5 0.0 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) MethyTransf_Reg PF10119.4 AAS50405.1 - 0.076 13.5 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Predicted methyltransferase regulatory domain SRP54 PF00448.17 AAS50406.2 - 6.2e-78 260.7 1.1 6.2e-78 260.7 0.8 1.9 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 AAS50406.2 - 3.7e-23 81.7 9.4 3.7e-23 81.7 6.5 3.8 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.14 AAS50406.2 - 4.5e-10 39.4 0.9 1.1e-09 38.2 0.6 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 AAS50406.2 - 3.2e-07 30.3 0.0 1.2e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 AAS50406.2 - 1.4e-06 27.8 0.9 8.4e-06 25.3 0.3 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 AAS50406.2 - 3.5e-05 23.3 0.7 0.00019 20.9 0.2 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 AAS50406.2 - 0.00011 21.9 0.1 0.00028 20.5 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.1 AAS50406.2 - 0.00013 21.9 0.1 0.1 12.4 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.1 AAS50406.2 - 0.00028 20.5 0.2 0.00099 18.7 0.2 2.0 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AAS50406.2 - 0.00071 19.1 0.1 0.0017 17.8 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain VirE PF05272.6 AAS50406.2 - 0.0023 17.4 0.1 0.0057 16.1 0.1 1.6 1 0 0 1 1 1 1 Virulence-associated protein E AAA_17 PF13207.1 AAS50406.2 - 0.0023 18.7 0.0 0.006 17.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain ArgK PF03308.11 AAS50406.2 - 0.0043 15.8 0.1 0.012 14.3 0.0 1.7 1 1 0 1 1 1 1 ArgK protein APS_kinase PF01583.15 AAS50406.2 - 0.0073 15.9 0.0 0.024 14.3 0.0 1.9 1 0 0 1 1 1 1 Adenylylsulphate kinase LigB PF02900.13 AAS50406.2 - 0.0076 15.2 0.0 0.26 10.2 0.0 2.3 2 0 0 2 2 2 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase SRPRB PF09439.5 AAS50406.2 - 0.0079 15.4 0.5 3.8 6.6 0.0 3.3 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA PF00004.24 AAS50406.2 - 0.014 15.6 0.8 0.42 10.8 0.5 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2209 PF09974.4 AAS50406.2 - 0.019 15.0 0.1 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) AAA_22 PF13401.1 AAS50406.2 - 0.022 14.8 0.2 0.22 11.6 0.2 2.9 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 AAS50406.2 - 0.024 13.8 0.1 0.36 10.0 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.1 AAS50406.2 - 0.14 12.1 0.1 0.4 10.6 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 AAS50406.2 - 0.14 12.1 0.5 1.3 8.9 0.1 2.6 2 1 0 2 2 2 0 AAA domain TMF_DNA_bd PF12329.3 AAS50407.1 - 0.00038 20.1 5.9 0.00038 20.1 4.1 3.6 1 1 2 4 4 4 1 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 AAS50407.1 - 0.0068 16.3 1.7 0.0068 16.3 1.1 4.1 2 1 1 3 3 3 2 bZIP transcription factor Spc7 PF08317.6 AAS50407.1 - 0.0089 14.7 18.4 0.013 14.1 12.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.7 AAS50407.1 - 0.031 14.0 8.1 0.25 11.1 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMP_2 PF06791.8 AAS50407.1 - 0.045 13.3 2.3 0.061 12.9 0.2 2.1 1 1 1 2 2 2 0 Prophage tail length tape measure protein Filament PF00038.16 AAS50407.1 - 0.049 13.0 26.2 0.3 10.4 5.8 2.4 1 1 1 2 2 2 0 Intermediate filament protein DUF2762 PF10960.3 AAS50407.1 - 0.26 11.0 6.0 1.8 8.3 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) Aconitase_C PF00694.14 AAS50407.1 - 0.32 11.1 3.0 0.38 10.8 0.3 2.3 2 1 1 3 3 3 0 Aconitase C-terminal domain DUF4201 PF13870.1 AAS50407.1 - 1.1 8.6 27.1 1.7 8.0 13.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) ATG16 PF08614.6 AAS50407.1 - 1.2 8.8 21.9 3.6 7.3 6.6 2.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 AAS50407.1 - 1.3 8.1 5.5 2.2 7.3 3.0 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Snapin_Pallidin PF14712.1 AAS50407.1 - 1.3 9.3 19.2 0.28 11.5 2.4 3.6 2 1 2 4 4 4 0 Snapin/Pallidin FUSC PF04632.7 AAS50407.1 - 1.4 7.2 2.8 2.3 6.5 2.0 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF948 PF06103.6 AAS50407.1 - 1.5 8.7 10.4 3.4 7.5 0.7 3.2 1 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 AAS50407.1 - 2.1 7.8 28.1 26 4.3 16.0 2.3 1 1 1 2 2 2 0 IncA protein DUF3450 PF11932.3 AAS50407.1 - 2.2 7.4 21.5 0.45 9.7 4.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.6 AAS50407.1 - 2.6 8.0 5.8 11 5.9 0.1 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CALCOCO1 PF07888.6 AAS50407.1 - 2.9 6.0 18.6 2.5 6.2 11.4 1.8 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMPIT PF07851.8 AAS50407.1 - 3.4 6.6 14.8 3.1 6.7 5.0 2.2 1 1 1 2 2 2 0 TMPIT-like protein APG6 PF04111.7 AAS50407.1 - 3.7 6.4 27.6 1.5 7.7 10.6 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 HALZ PF02183.13 AAS50407.1 - 4.8 6.9 23.7 6.1 6.6 1.0 4.9 4 1 1 5 5 5 0 Homeobox associated leucine zipper Val_tRNA-synt_C PF10458.4 AAS50407.1 - 6 7.0 8.1 2.3 8.3 0.8 3.4 4 0 0 4 4 3 0 Valyl tRNA synthetase tRNA binding arm DUF4200 PF13863.1 AAS50407.1 - 8.1 6.4 26.9 2.7 7.9 2.7 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Glyco_transf_22 PF03901.12 AAS50408.1 - 3.2e-32 112.0 15.8 4.4e-32 111.6 10.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family cobW PF02492.14 AAS50409.1 - 2.7e-42 144.2 0.0 3.6e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 AAS50409.1 - 0.0002 21.3 0.0 0.00042 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 AAS50409.1 - 0.00022 21.5 0.1 0.00063 20.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain CobW_C PF07683.9 AAS50409.1 - 0.00052 19.6 0.1 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_29 PF13555.1 AAS50409.1 - 0.00087 18.7 0.2 0.0088 15.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 AAS50409.1 - 0.0023 17.3 0.7 0.054 12.9 0.5 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 AAS50409.1 - 0.0036 17.0 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 AAS50409.1 - 0.015 16.1 0.2 0.12 13.2 0.1 2.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 AAS50409.1 - 0.023 14.6 0.1 0.051 13.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 AAS50409.1 - 0.03 14.6 1.5 0.043 14.1 0.2 1.8 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 AAS50409.1 - 0.04 13.6 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 AAS50409.1 - 0.054 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AAS50409.1 - 0.068 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Pro_isomerase PF00160.16 AAS50410.1 - 1.3e-27 96.8 0.1 2e-27 96.3 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4117 PF13491.1 AAS50410.1 - 0.12 11.8 0.1 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4117) Lipase_3 PF01764.20 AAS50411.1 - 8.3e-09 35.1 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 AAS50411.1 - 0.00037 20.2 0.0 0.0028 17.4 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AAS50411.1 - 0.00086 19.2 0.3 0.0027 17.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.7 AAS50411.1 - 0.027 14.1 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.15 AAS50411.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 AAS50411.1 - 0.089 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 AAS50411.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Phos_pyr_kin PF08543.7 AAS50412.1 - 5.3e-08 32.3 0.0 7.4e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 AAS50412.1 - 6.2e-08 32.1 0.5 1.4e-07 30.9 0.1 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase HTH_18 PF12833.2 AAS50412.1 - 0.018 15.1 0.0 0.057 13.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain WD40 PF00400.27 AAS50413.1 - 6.3e-07 29.0 0.0 0.0011 18.7 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-C3HC4 PF00097.20 AAS50414.1 - 1.6e-10 40.4 15.9 3.5e-10 39.3 7.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS50414.1 - 1.1e-09 38.1 11.2 1.1e-09 38.1 7.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 AAS50414.1 - 3.5e-09 35.9 0.0 8.8e-09 34.6 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-RING_5 PF14634.1 AAS50414.1 - 5.1e-08 32.5 13.4 2.6e-07 30.2 6.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 AAS50414.1 - 5.1e-08 32.5 4.0 1.2e-07 31.3 2.8 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 AAS50414.1 - 6.1e-08 32.4 13.8 1.8e-07 30.8 7.3 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 AAS50414.1 - 7.3e-08 32.1 14.3 1.2e-07 31.4 7.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 AAS50414.1 - 1.6e-07 30.8 11.9 3.8e-07 29.6 5.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AAS50414.1 - 3.8e-05 23.2 8.0 3.8e-05 23.2 5.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 AAS50414.1 - 5e-05 23.3 6.2 7.7e-05 22.7 2.4 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger U-box PF04564.10 AAS50414.1 - 0.069 13.1 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 U-box domain zf-Di19 PF05605.7 AAS50414.1 - 0.14 12.3 4.1 3.5 7.8 0.0 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-Nse PF11789.3 AAS50414.1 - 0.27 10.7 13.3 0.033 13.7 4.0 2.6 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 AAS50414.1 - 0.46 10.3 4.8 0.23 11.2 1.7 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 AAS50414.1 - 1.2 8.6 7.9 0.66 9.5 1.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 AAS50414.1 - 2 8.0 12.5 0.41 10.2 4.4 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Fork_head PF00250.13 AAS50415.1 - 3.7e-33 113.4 0.0 7.8e-33 112.3 0.0 1.5 2 0 0 2 2 2 1 Fork head domain G10 PF01125.12 AAS50416.2 - 2.5e-55 186.0 0.1 2.7e-55 185.9 0.1 1.0 1 0 0 1 1 1 1 G10 protein Ytp1 PF10355.4 AAS50417.1 - 1.1e-108 362.5 4.1 1.7e-108 361.9 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 AAS50417.1 - 8.7e-28 95.9 3.4 8.7e-28 95.9 2.4 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Glucan_synthase PF02364.10 AAS50418.1 - 1.1e-303 1009.3 1.8 1.5e-303 1008.7 1.2 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 AAS50418.1 - 4.9e-31 107.0 0.2 1.4e-30 105.6 0.2 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF4640 PF15480.1 AAS50418.1 - 0.0021 17.7 0.3 0.01 15.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4640) TPR_11 PF13414.1 AAS50419.1 - 9.5e-15 54.0 0.5 1.3e-14 53.5 0.4 1.2 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 AAS50419.1 - 3.7e-08 32.6 0.7 0.0046 16.5 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 AAS50419.1 - 1.3e-07 30.9 1.0 0.0017 18.1 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 AAS50419.1 - 2.5e-05 24.1 0.1 0.014 15.3 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 AAS50419.1 - 7.8e-05 22.1 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 AAS50419.1 - 0.00021 21.8 0.0 0.00035 21.1 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 AAS50419.1 - 0.00032 20.9 0.2 0.00062 20.0 0.1 1.5 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 AAS50419.1 - 0.00097 18.7 0.5 1.2 9.0 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 AAS50419.1 - 0.0015 18.5 0.1 0.0027 17.8 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 AAS50419.1 - 0.0021 18.1 2.1 0.065 13.4 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 AAS50419.1 - 0.0077 16.1 0.3 0.16 11.9 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.2 AAS50419.1 - 0.029 14.1 0.1 0.077 12.8 0.1 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.1 AAS50419.1 - 0.033 14.0 0.3 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat UPF0029 PF01205.14 AAS50420.1 - 7.2e-30 102.9 0.0 1.1e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 AAS50420.1 - 4.3e-12 45.9 1.1 6.2e-12 45.4 0.4 1.5 2 0 0 2 2 2 1 RWD domain Utp14 PF04615.8 AAS50421.1 - 0.0014 16.8 2.0 0.0017 16.6 1.4 1.1 1 0 0 1 1 1 1 Utp14 protein MPP6 PF10175.4 AAS50421.1 - 0.0094 16.3 0.2 0.016 15.5 0.1 1.4 1 0 0 1 1 1 1 M-phase phosphoprotein 6 DUF4317 PF14199.1 AAS50421.1 - 0.11 11.3 0.1 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) ACC_epsilon PF13822.1 AAS50421.1 - 0.85 10.0 6.0 2.9 8.3 0.2 2.6 2 1 1 3 3 3 0 Acyl-CoA carboxylase epsilon subunit WD40 PF00400.27 AAS50422.1 - 1.1e-55 183.6 11.3 1.7e-12 46.7 0.2 12.5 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 AAS50422.1 - 2.1e-31 108.0 0.1 3.3e-31 107.4 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nbas_N PF15492.1 AAS50422.1 - 2.9e-05 23.2 0.2 0.61 9.1 0.0 4.2 3 1 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal SGL PF08450.7 AAS50422.1 - 5.5e-05 22.6 0.5 0.4 10.0 0.0 3.5 2 1 1 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Cytochrom_D1 PF02239.11 AAS50422.1 - 0.0086 14.4 0.4 0.49 8.6 0.0 3.7 3 2 1 4 4 4 1 Cytochrome D1 heme domain Atx10homo_assoc PF09759.4 AAS50423.1 - 4.7e-41 138.6 1.2 1.4e-40 137.1 0.2 2.2 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Thr_synth_N PF14821.1 AAS50424.1 - 2.1e-25 88.5 0.0 7.6e-25 86.7 0.0 2.0 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 AAS50424.1 - 4.2e-16 59.0 0.0 6.8e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACCA PF03255.9 AAS50425.1 - 0.11 12.0 0.7 0.86 9.1 0.0 2.6 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Ribosomal_L9_N PF01281.14 AAS50426.1 - 7.9e-05 21.8 0.0 0.00019 20.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain PilJ PF13675.1 AAS50426.1 - 0.0051 17.1 0.1 0.0083 16.4 0.1 1.5 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1682 PF07946.9 AAS50427.1 - 1e-88 297.2 0.4 1.2e-88 297.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ank_5 PF13857.1 AAS50428.1 - 2e-18 65.9 3.3 7.2e-15 54.6 0.9 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 AAS50428.1 - 1.1e-16 60.7 4.3 2.9e-08 34.0 0.4 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 AAS50428.1 - 2e-14 53.6 0.9 2.1e-12 47.1 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AAS50428.1 - 1.7e-13 49.6 5.8 7.2e-07 28.7 0.2 4.9 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 AAS50428.1 - 1.6e-10 40.2 0.3 8.3e-05 22.4 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Peptidase_M76 PF09768.4 AAS50429.1 - 1.3e-74 249.3 2.0 1.7e-74 249.0 1.4 1.1 1 0 0 1 1 1 1 Peptidase M76 family Dicty_spore_N PF04562.7 AAS50429.1 - 0.037 14.3 0.3 0.037 14.3 0.2 1.7 2 0 0 2 2 2 0 Dictyostelium spore coat protein, N terminus Chromo PF00385.19 AAS50429.1 - 0.061 13.0 1.0 0.12 12.0 0.1 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain MBOAT PF03062.14 AAS50430.1 - 5.9e-54 183.3 38.5 7.9e-54 182.9 26.7 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 AAS50430.1 - 0.005 16.8 4.9 0.005 16.8 3.4 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family WBS_methylT PF12589.3 AAS50431.1 - 7.3e-17 61.6 6.7 1.4e-16 60.7 4.6 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 AAS50431.1 - 2.5e-12 47.1 0.1 6.9e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AAS50431.1 - 1.2e-06 28.8 0.0 6e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS50431.1 - 1.4e-05 24.7 0.0 3.4e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AAS50431.1 - 2.1e-05 24.9 0.0 6.7e-05 23.2 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AAS50431.1 - 2.2e-05 24.2 0.0 3.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS50431.1 - 9.2e-05 22.9 0.0 0.0002 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AAS50431.1 - 0.00034 20.6 0.2 0.0011 18.9 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 AAS50431.1 - 0.0024 17.0 0.1 0.061 12.3 0.0 2.4 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.8 AAS50431.1 - 0.0032 17.5 0.0 0.0081 16.2 0.0 1.7 2 0 0 2 2 1 1 Predicted AdoMet-dependent methyltransferase PCMT PF01135.14 AAS50431.1 - 0.0038 16.7 0.0 0.017 14.6 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 AAS50431.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.8 AAS50431.1 - 0.019 14.0 0.2 0.095 11.8 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 AAS50431.1 - 0.084 12.5 0.2 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_L19 PF01245.15 AAS50432.1 - 3.7e-11 42.8 0.1 5.2e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 HIG_1_N PF04588.8 AAS50433.1 - 4.4e-05 23.1 0.6 9.1e-05 22.1 0.4 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Peptidase_S8 PF00082.17 AAS50434.2 - 1.6e-46 158.7 0.8 2.3e-46 158.1 0.6 1.2 1 0 0 1 1 1 1 Subtilase family PAZ_siRNAbind PF12212.3 AAS50434.2 - 0.12 12.0 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain Nop14 PF04147.7 AAS50434.2 - 0.3 8.9 17.3 0.41 8.5 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 AAS50434.2 - 0.87 8.8 15.2 1.3 8.2 10.5 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 AAS50434.2 - 0.88 8.5 10.3 1.7 7.5 7.2 1.5 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.7 AAS50434.2 - 3.8 7.1 10.9 6.1 6.4 7.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 AAS50434.2 - 7.1 4.9 16.1 13 4.1 11.1 1.3 1 0 0 1 1 1 0 Daxx Family Tim17 PF02466.14 AAS50435.1 - 1.8e-27 95.8 2.1 2.5e-27 95.4 1.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 AAS50435.1 - 0.00038 20.5 2.4 0.041 13.9 0.0 2.5 2 0 0 2 2 2 2 Bacteriocin class II with double-glycine leader peptide ACC_central PF08326.7 AAS50436.1 - 1.2e-265 883.0 0.1 1.7e-265 882.6 0.1 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 AAS50436.1 - 3e-175 583.2 0.0 4e-175 582.8 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 AAS50436.1 - 2.2e-51 174.1 0.0 4.6e-51 173.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 AAS50436.1 - 4.8e-25 87.7 0.0 1e-24 86.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 AAS50436.1 - 1.1e-20 73.6 0.0 1.3e-19 70.1 0.0 2.8 3 0 0 3 3 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 AAS50436.1 - 3.8e-16 58.4 0.0 2e-15 56.1 0.0 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 AAS50436.1 - 6.7e-11 42.2 0.0 1e-09 38.3 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AAS50436.1 - 9e-08 31.2 0.0 1.1e-05 24.3 0.0 3.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 AAS50436.1 - 0.00016 21.1 0.0 0.00062 19.2 0.0 2.0 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 AAS50436.1 - 0.014 15.2 0.0 0.095 12.5 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 AAS50436.1 - 0.018 14.6 0.1 0.58 9.8 0.0 2.9 2 1 1 3 3 3 0 Biotin-lipoyl like ATP-grasp PF02222.17 AAS50436.1 - 0.049 12.9 0.1 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain RHH_1 PF01402.16 AAS50436.1 - 9.1 6.3 9.1 40 4.3 1.4 4.1 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family Dus PF01207.12 AAS50437.1 - 2.2e-50 171.2 0.0 4.6e-50 170.2 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF1708 PF08101.6 AAS50438.1 - 8.9e-96 321.2 0.2 1.2e-95 320.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) PRELI PF04707.9 AAS50440.1 - 8.8e-42 142.3 0.0 1e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family DUF3176 PF11374.3 AAS50441.1 - 0.12 12.2 2.1 0.13 12.1 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3176) DNA_pol_viral_N PF00242.12 AAS50441.1 - 6.7 5.6 10.6 9.5 5.1 7.4 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain NMT PF01233.14 AAS50442.1 - 4.5e-80 266.9 0.0 7e-80 266.3 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 AAS50442.1 - 3.9e-77 257.9 0.1 1e-76 256.5 0.0 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 AAS50442.1 - 3.2e-05 23.7 0.0 0.00069 19.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AAS50442.1 - 0.0042 17.2 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain WD40 PF00400.27 AAS50443.1 - 5.3e-16 57.8 9.8 1.8e-05 24.4 0.2 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 AAS50443.1 - 0.0016 16.6 0.2 0.0029 15.8 0.1 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 CMV_1a PF12467.3 AAS50443.1 - 0.17 12.2 2.3 0.81 10.0 0.3 2.2 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family ATG22 PF11700.3 AAS50445.2 - 3.5e-117 391.8 20.4 4e-117 391.6 14.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Ammonium_transp PF00909.16 AAS50447.1 - 1.3e-116 389.4 21.7 1.4e-116 389.2 15.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family 7TM_GPCR_Sri PF10327.4 AAS50447.1 - 0.0068 15.3 0.0 0.02 13.8 0.0 1.7 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri Metallophos PF00149.23 AAS50448.2 - 2.4e-36 125.0 0.1 3.3e-36 124.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 AAS50448.2 - 4.3e-16 58.3 4.7 3.7e-14 52.1 1.4 2.9 2 1 1 3 3 3 2 TPR repeat PPP5 PF08321.7 AAS50448.2 - 1.2e-10 41.2 0.0 1.3e-08 34.7 0.0 2.6 1 1 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.23 AAS50448.2 - 1.2e-07 31.0 4.2 0.0019 17.6 0.2 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 AAS50448.2 - 1.8e-07 30.5 4.4 0.01 15.7 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 AAS50448.2 - 0.00012 21.9 0.1 1.3 9.4 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 AAS50448.2 - 0.002 17.9 5.0 0.0069 16.2 0.5 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 AAS50448.2 - 0.1 12.4 2.8 1.1 9.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 AAS50448.2 - 0.13 12.6 0.8 0.35 11.2 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 AAS50448.2 - 0.45 10.4 3.9 11 6.0 0.2 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 AAS50448.2 - 0.88 10.3 6.9 0.55 10.9 1.8 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 AAS50448.2 - 3.4 8.5 7.3 27 5.7 0.2 4.0 1 1 1 3 3 3 0 Tetratricopeptide repeat ADH_N PF08240.7 AAS50449.2 - 1.1e-30 105.6 0.4 2.4e-30 104.4 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AAS50449.2 - 3.8e-30 104.0 1.3 5.4e-30 103.6 0.9 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AAS50449.2 - 2.5e-05 25.1 0.2 5.6e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TRAM_LAG1_CLN8 PF03798.11 AAS50450.1 - 4.9e-28 98.0 11.2 4.9e-28 98.0 7.7 1.7 2 0 0 2 2 2 1 TLC domain PH PF00169.24 AAS50451.1 - 4.3e-18 65.4 0.1 1.6e-17 63.6 0.1 2.1 1 0 0 1 1 1 1 PH domain Flavin_Reduct PF01613.13 AAS50452.1 - 6.5e-26 91.0 0.3 1.6e-25 89.7 0.2 1.6 1 1 0 1 1 1 1 Flavin reductase like domain Peptidase_C50 PF03568.12 AAS50454.2 - 4.2e-135 450.3 0.4 8.4e-135 449.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase family C50 Telomere_reg-2 PF10193.4 AAS50455.1 - 4.4e-23 81.7 2.6 1.2e-22 80.3 1.8 1.8 1 0 0 1 1 1 1 Telomere length regulation protein RabGAP-TBC PF00566.13 AAS50456.1 - 2.6e-50 170.8 1.2 9.1e-50 169.0 0.1 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.15 AAS50456.1 - 7.8e-14 50.9 0.0 1.9e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.3 AAS50456.1 - 0.0043 16.8 0.1 0.017 14.8 0.0 2.1 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 EF-hand_6 PF13405.1 AAS50456.1 - 0.046 13.6 0.1 21 5.3 0.0 3.2 2 0 0 2 2 2 0 EF-hand domain Rhomboid PF01694.17 AAS50457.2 - 1.5e-29 102.9 15.3 1.5e-29 102.9 10.6 2.0 2 0 0 2 2 2 1 Rhomboid family Romo1 PF10247.4 AAS50457.2 - 0.08 13.1 1.7 5.2 7.3 0.1 3.1 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 SelB-wing_1 PF09105.5 AAS50458.1 - 0.09 12.4 0.4 0.98 9.1 0.1 2.5 3 0 0 3 3 3 0 Elongation factor SelB, winged helix Pescadillo_N PF06732.6 AAS50459.1 - 1.6e-120 401.6 1.9 1.6e-120 401.6 1.3 2.5 2 1 1 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 AAS50459.1 - 7.1e-10 38.9 0.0 2.1e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Med18 PF09637.5 AAS50460.1 - 3.1e-71 239.8 0.0 3.5e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Med18 protein RecO_C PF02565.10 AAS50460.1 - 0.064 13.1 0.1 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 Recombination protein O C terminal VMA21 PF09446.5 AAS50461.1 - 5.7e-16 58.1 9.4 7.1e-16 57.8 6.5 1.1 1 0 0 1 1 1 1 VMA21-like domain DUF21 PF01595.15 AAS50461.1 - 0.014 14.6 0.3 0.015 14.5 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF21 ATP-synt_S1 PF05827.7 AAS50462.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) MDMPI_C PF07398.6 AAS50462.1 - 0.27 11.8 1.8 23 5.6 0.0 2.6 3 0 0 3 3 3 0 MDMPI C-terminal domain IF-2B PF01008.12 AAS50463.1 - 1.1e-70 237.7 0.0 1.4e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Cyclin_N PF00134.18 AAS50464.1 - 7.8e-40 135.3 0.2 2.4e-39 133.7 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AAS50464.1 - 8.6e-31 106.3 0.2 1e-29 102.8 0.0 2.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 AAS50465.1 - 1.7e-39 134.2 2.4 2.8e-39 133.5 1.6 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AAS50465.1 - 1.3e-15 57.3 0.8 2.6e-15 56.3 0.1 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain WD40 PF00400.27 AAS50467.1 - 5.6e-25 86.2 1.6 3.2e-07 29.9 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF3639 PF12341.3 AAS50468.1 - 2.4e-08 33.8 0.3 5.3e-08 32.7 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) BBS2_Mid PF14783.1 AAS50468.1 - 0.0023 17.7 0.0 14 5.5 0.0 3.9 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 AAS50468.1 - 0.003 17.0 0.0 1.1 8.6 0.0 3.1 3 1 0 3 3 3 2 PQQ-like domain DNA_gyraseA_C PF03989.8 AAS50468.1 - 0.02 14.1 0.0 0.22 10.8 0.0 2.6 3 0 0 3 3 3 0 DNA gyrase C-terminal domain, beta-propeller Apc4_WD40 PF12894.2 AAS50468.1 - 0.038 13.4 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 AAS50468.1 - 0.057 13.3 5.9 15 5.6 0.0 5.7 6 1 0 6 6 6 0 WD domain, G-beta repeat COG2 PF06148.6 AAS50469.1 - 2.9e-06 27.1 6.9 2.9e-06 27.1 4.8 1.7 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_L PF02601.10 AAS50469.1 - 0.0021 17.3 1.7 0.0024 17.1 1.2 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit PRD PF00874.15 AAS50469.1 - 0.041 13.9 0.5 2.4 8.3 0.0 2.5 2 0 0 2 2 2 0 PRD domain Hemerythrin PF01814.18 AAS50469.1 - 0.25 11.5 3.1 0.31 11.1 0.9 2.0 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain MCM_N PF14551.1 AAS50469.1 - 0.3 11.5 2.9 7 7.1 2.0 2.8 1 1 0 1 1 1 0 MCM N-terminal domain Baculo_PEP_C PF04513.7 AAS50469.1 - 0.51 10.1 3.8 1.2 8.9 2.0 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med4 PF10018.4 AAS50469.1 - 0.58 9.5 5.3 6.3 6.1 3.2 2.2 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF904 PF06005.7 AAS50469.1 - 1.4 9.2 5.9 1 9.7 0.7 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF904) Nup54 PF13874.1 AAS50470.1 - 1.2e-41 141.6 3.1 3.2e-41 140.2 2.1 1.6 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 AAS50470.1 - 1.8e-27 95.8 224.2 3.3e-09 36.9 28.5 5.6 1 1 4 5 5 5 5 Nucleoporin FG repeat region Tom5 PF10642.4 AAS50471.1 - 1.7e-27 94.7 0.9 1.8e-27 94.6 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Med26 PF08711.6 AAS50472.1 - 5.5e-13 48.1 0.1 1.4e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ribosom_S12_S23 PF00164.20 AAS50473.1 - 5.8e-41 138.7 0.7 6.8e-41 138.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF2611 PF11022.3 AAS50474.1 - 3.2e-22 78.4 0.0 3.4e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) RNA_Me_trans PF04252.8 AAS50475.1 - 1.6e-72 243.0 0.0 1.8e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DDHD PF02862.12 AAS50476.1 - 2.6e-37 128.7 0.8 2.5e-25 89.6 0.0 2.6 2 1 1 3 3 3 2 DDHD domain LCAT PF02450.10 AAS50476.1 - 6.2e-05 22.1 0.1 0.001 18.1 0.0 2.1 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 AAS50476.1 - 0.00016 21.0 0.2 0.009 15.3 0.0 2.2 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF2305 PF10230.4 AAS50476.1 - 0.043 13.2 0.1 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 AAS50476.1 - 0.046 13.5 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.8 AAS50476.1 - 0.074 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 AAS50476.1 - 0.12 12.1 0.0 0.47 10.1 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family ISN1 PF06437.6 AAS50478.1 - 7.2e-175 581.5 0.0 8.3e-175 581.3 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Choline_transpo PF04515.7 AAS50479.1 - 3.1e-100 335.1 20.3 3.1e-100 335.1 14.1 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter ATP-synt_8 PF00895.15 AAS50479.1 - 1.2 9.3 0.0 1.2 9.3 0.0 4.4 3 1 1 4 4 4 0 ATP synthase protein 8 Xpo1 PF08389.7 AAS50481.2 - 3.1e-29 101.8 2.5 2.9e-28 98.6 0.2 3.5 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 AAS50481.2 - 2.4e-07 30.5 1.8 2.5e-05 24.1 0.0 3.3 1 1 1 2 2 2 1 Importin-beta N-terminal domain CDT1 PF08839.6 AAS50481.2 - 0.027 14.3 0.1 0.4 10.5 0.0 2.7 3 0 0 3 3 3 0 DNA replication factor CDT1 like LSM PF01423.17 AAS50482.1 - 3.7e-13 48.7 0.2 4.4e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain A_deaminase_N PF08451.6 AAS50483.1 - 0.72 9.9 4.5 1.1 9.3 1.8 2.1 1 1 1 2 2 2 0 Adenosine/AMP deaminase N-terminal TRAPPC9-Trs120 PF08626.6 AAS50484.1 - 1.7e-223 744.4 0.0 4.1e-223 743.1 0.0 1.5 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit IL6Ra-bind PF09240.5 AAS50484.1 - 0.091 12.9 1.4 1.4 9.1 0.1 2.5 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding Proteasome PF00227.21 AAS50485.1 - 2e-44 151.1 0.0 2.5e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 AAS50485.1 - 1e-11 43.9 0.1 2.1e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal MCH PF02289.11 AAS50485.1 - 0.0067 15.5 0.0 0.0094 15.0 0.0 1.2 1 0 0 1 1 1 1 Cyclohydrolase (MCH) Formyl_trans_N PF00551.14 AAS50486.2 - 3.8e-50 169.9 0.0 4.4e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.13 AAS50486.2 - 0.017 14.7 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Glyco_trans_4_4 PF13579.1 AAS50486.2 - 0.02 15.0 1.7 0.033 14.3 1.1 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain PINIT PF14324.1 AAS50487.1 - 6.3e-32 110.6 0.0 1.2e-31 109.6 0.0 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 AAS50487.1 - 7e-21 73.4 6.4 1.3e-20 72.6 4.4 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 AAS50487.1 - 6e-13 47.9 0.0 1.1e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 AAS50487.1 - 1.2e-06 27.8 2.1 2.9e-06 26.6 1.5 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 AAS50487.1 - 0.031 13.9 2.3 0.054 13.1 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS50487.1 - 0.043 13.8 3.3 0.078 13.0 2.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cwf_Cwc_15 PF04889.7 AAS50487.1 - 0.14 11.8 8.2 0.28 10.8 5.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-C3HC4_4 PF15227.1 AAS50487.1 - 0.18 11.7 3.7 0.32 10.9 2.6 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 AAS50487.1 - 0.21 11.2 0.8 0.37 10.4 0.3 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AAS50487.1 - 0.32 10.8 3.1 0.57 10.0 2.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.1 AAS50487.1 - 0.64 9.7 5.5 0.24 11.1 0.3 2.4 2 0 0 2 2 2 0 RING-type zinc-finger ICMT PF04140.9 AAS50488.1 - 2.9e-27 94.7 0.9 6.5e-27 93.5 0.6 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 AAS50488.1 - 1.2e-15 57.4 1.8 1.2e-15 57.4 1.3 2.4 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.7 AAS50488.1 - 1.9e-05 24.0 1.5 2.5e-05 23.6 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.6 AAS50488.1 - 0.0054 16.1 1.5 0.0092 15.3 1.0 1.3 1 0 0 1 1 1 1 NnrU protein zf-HIT PF04438.11 AAS50489.1 - 0.0088 15.6 11.2 0.0088 15.6 7.7 1.8 2 0 0 2 2 2 1 HIT zinc finger Carn_acyltransf PF00755.15 AAS50490.1 - 1.1e-169 565.2 0.0 1.3e-169 565.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF3940 PF13076.1 AAS50490.1 - 0.15 11.6 1.9 0.16 11.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3940) DER1 PF04511.10 AAS50491.1 - 1.2e-27 96.7 3.3 1.5e-27 96.4 2.3 1.1 1 0 0 1 1 1 1 Der1-like family Thioredoxin PF00085.15 AAS50491.1 - 3.3e-23 81.3 0.0 5.7e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AAS50491.1 - 3.1e-05 24.1 0.1 0.00045 20.4 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AAS50491.1 - 0.0044 17.1 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 AAS50491.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.1 AAS50491.1 - 0.059 12.9 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.1 AAS50491.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Nop25 PF09805.4 AAS50492.1 - 1.8e-32 112.2 11.7 1.8e-32 112.2 8.1 2.4 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) T2SM PF04612.7 AAS50492.1 - 1.3 8.7 7.2 56 3.4 5.0 2.8 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein M EXS PF03124.9 AAS50493.1 - 4.2e-70 236.4 13.4 4.9e-70 236.2 9.3 1.0 1 0 0 1 1 1 1 EXS family Ribosomal_L2_C PF03947.13 AAS50494.1 - 4.4e-48 162.3 1.9 8.6e-48 161.4 1.3 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 AAS50494.1 - 8.5e-28 96.1 0.5 2.1e-27 94.8 0.4 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Peptidase_M28 PF04389.12 AAS50495.1 - 5.7e-27 94.5 0.4 8.2e-27 94.0 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 AAS50495.1 - 8.4e-06 25.4 0.1 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 RE_Eco47II PF09553.5 AAS50495.1 - 0.0088 15.1 0.1 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Eco47II restriction endonuclease Acylphosphatase PF00708.13 AAS50495.1 - 0.063 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Acylphosphatase ATP-synt_D PF01813.12 AAS50496.1 - 1e-63 214.4 3.9 1.4e-63 214.0 2.7 1.2 1 0 0 1 1 1 1 ATP synthase subunit D RICH PF05062.7 AAS50496.1 - 0.066 13.3 2.6 0.16 12.0 0.4 2.3 2 0 0 2 2 2 0 RICH domain Nup54 PF13874.1 AAS50496.1 - 2 8.0 5.9 1.2 8.7 0.1 2.5 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 DUF1640 PF07798.6 AAS50496.1 - 2.8 7.9 7.5 0.4 10.7 1.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) TPR_15 PF13429.1 AAS50497.2 - 3.6e-09 36.0 9.8 0.03 13.3 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 AAS50497.2 - 6.8e-08 32.4 25.5 0.12 13.0 0.1 11.0 8 3 3 11 11 11 1 Tetratricopeptide repeat TPR_19 PF14559.1 AAS50497.2 - 1e-06 28.9 16.4 0.01 16.1 0.0 5.6 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 AAS50497.2 - 4.5e-05 23.0 6.5 2.2 7.9 0.0 5.4 6 0 0 6 6 6 2 TPR repeat TPR_8 PF13181.1 AAS50497.2 - 0.00014 21.3 0.4 0.33 10.8 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 AAS50497.2 - 0.00015 21.3 5.1 0.61 10.1 0.0 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat Suf PF05843.9 AAS50497.2 - 0.0007 19.4 1.4 1.2 8.8 0.0 3.9 4 0 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_6 PF13174.1 AAS50497.2 - 0.0067 16.8 1.4 1.9 9.1 0.1 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat ACDC PF14733.1 AAS50497.2 - 0.01 15.9 0.1 0.066 13.3 0.0 2.4 1 0 0 1 1 1 0 AP2-coincident C-terminal Mad3_BUB1_I PF08311.7 AAS50497.2 - 0.015 15.0 10.4 1.9 8.2 0.1 5.9 6 2 1 7 7 7 0 Mad3/BUB1 homology region 1 Apc3 PF12895.2 AAS50497.2 - 0.015 15.3 11.5 1.9 8.7 0.0 4.2 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 AAS50497.2 - 0.059 13.3 19.1 0.46 10.4 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat EIAV_Rev PF11129.3 AAS50497.2 - 0.076 12.9 0.5 0.29 11.1 0.3 2.0 2 0 0 2 2 1 0 Rev protein of equine infectious anaemia virus TPR_17 PF13431.1 AAS50497.2 - 0.082 13.1 2.7 84 3.7 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 AAS50497.2 - 0.46 10.4 4.5 7.2 6.6 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat AFG1_ATPase PF03969.11 AAS50498.1 - 1.7e-75 254.1 0.0 1.1e-71 241.5 0.0 2.8 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 AAS50498.1 - 2.2e-05 24.5 1.0 0.0054 16.7 0.5 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AAS50498.1 - 0.0005 20.2 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 AAS50498.1 - 0.019 15.1 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 AAS50498.1 - 0.024 14.3 0.0 0.048 13.3 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 AAS50498.1 - 0.036 13.8 0.0 0.084 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CheR_N PF03705.10 AAS50498.1 - 0.037 13.3 1.7 8.9 5.7 0.0 3.8 3 0 0 3 3 3 0 CheR methyltransferase, all-alpha domain RNA_helicase PF00910.17 AAS50498.1 - 0.095 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mak10 PF04112.8 AAS50499.1 - 1.2e-48 164.5 0.1 2.7e-48 163.3 0.0 1.7 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Spore_III_AB PF09548.5 AAS50499.1 - 0.0062 16.2 0.1 0.059 13.1 0.0 2.1 2 0 0 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) Ribosomal_L11_N PF03946.9 AAS50500.1 - 1.7e-17 62.5 0.3 6.2e-17 60.8 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 AAS50500.1 - 1.8e-10 40.7 0.7 3.2e-10 39.9 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain ACBP PF00887.14 AAS50501.1 - 1.3e-24 85.6 0.0 2.1e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein IMS PF00817.15 AAS50502.2 - 6.2e-42 142.9 0.0 1e-41 142.2 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 AAS50502.2 - 1.5e-11 44.2 0.0 2.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain MAP65_ASE1 PF03999.7 AAS50503.1 - 6e-73 246.4 28.6 9.2e-73 245.8 19.8 1.3 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Spore_III_AB PF09548.5 AAS50503.1 - 0.0056 16.4 0.4 0.0056 16.4 0.3 3.5 2 1 1 3 3 3 1 Stage III sporulation protein AB (spore_III_AB) SGS PF05002.10 AAS50504.1 - 9.7e-27 92.5 0.6 3.1e-26 90.9 0.1 2.1 2 0 0 2 2 2 1 SGS domain CS PF04969.11 AAS50504.1 - 4.4e-16 59.1 1.1 7.5e-16 58.4 0.3 1.7 2 0 0 2 2 2 1 CS domain TPR_11 PF13414.1 AAS50504.1 - 4.9e-05 22.9 7.2 0.0011 18.5 1.7 2.5 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 AAS50504.1 - 0.004 16.9 4.7 2.7 8.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 AAS50504.1 - 0.0048 16.8 0.4 0.0048 16.8 0.3 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 AAS50504.1 - 0.022 14.6 6.1 3.9 7.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 AAS50504.1 - 0.11 12.1 1.9 0.92 9.2 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AAS50504.1 - 0.33 11.7 10.2 0.88 10.3 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 AAS50504.1 - 2.3 8.6 12.8 0.33 11.3 0.5 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 AAS50504.1 - 9 6.3 7.3 24 5.0 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat NOB1_Zn_bind PF08772.6 AAS50505.1 - 1.9e-27 94.8 0.1 3.8e-27 93.9 0.1 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 AAS50505.1 - 0.0065 16.3 2.0 0.0065 16.3 1.4 1.9 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator DUF2011 PF09428.5 AAS50505.1 - 0.084 12.7 6.7 0.046 13.6 1.1 2.2 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) zf-TFIIB PF13453.1 AAS50505.1 - 0.087 12.0 0.8 0.2 10.8 0.5 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-RING_3 PF14369.1 AAS50505.1 - 0.15 12.1 1.1 0.35 10.9 0.7 1.6 1 0 0 1 1 1 0 zinc-finger Prp31_C PF09785.4 AAS50505.1 - 0.41 11.0 9.4 2.8 8.3 3.2 2.6 2 0 0 2 2 2 0 Prp31 C terminal domain Flavoprotein PF02441.14 AAS50506.1 - 1.9e-43 147.2 0.0 4.3e-43 146.0 0.0 1.6 1 1 0 1 1 1 1 Flavoprotein CENP-T PF15511.1 AAS50506.1 - 0.0051 16.1 14.7 0.0051 16.1 10.2 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T PPP4R2 PF09184.6 AAS50506.1 - 0.27 10.7 21.8 0.62 9.5 15.1 1.6 1 0 0 1 1 1 0 PPP4R2 Pox_Ag35 PF03286.9 AAS50506.1 - 1.3 8.5 15.4 2.6 7.5 10.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CIAPIN1 PF05093.8 AAS50507.1 - 6.4e-35 119.2 1.9 1.1e-34 118.5 1.3 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis zf-U1 PF06220.7 AAS50508.1 - 5.5e-18 64.2 5.5 5.5e-18 64.2 3.8 1.7 2 0 0 2 2 2 1 U1 zinc finger zf-C2H2_jaz PF12171.3 AAS50508.1 - 0.041 14.0 5.6 0.11 12.6 3.8 1.8 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding GTP_EFTU PF00009.22 AAS50509.1 - 5e-61 205.4 0.2 6.6e-61 205.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AAS50509.1 - 3.5e-27 94.4 0.1 8.2e-27 93.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AAS50509.1 - 7.3e-21 74.0 1.8 1.1e-20 73.4 0.6 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AAS50509.1 - 5.1e-05 23.1 0.0 9.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 AAS50509.1 - 0.00015 21.3 0.1 0.00036 20.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 AAS50509.1 - 0.0015 19.0 0.0 0.0025 18.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 AAS50509.1 - 0.039 13.4 0.5 7.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DisA_N PF02457.11 AAS50509.1 - 0.053 12.6 0.1 0.23 10.5 0.0 1.9 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding cobW PF02492.14 AAS50509.1 - 0.2 11.0 1.0 0.37 10.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 AAS50509.1 - 0.26 10.6 2.7 5.9 6.2 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain G_glu_transpept PF01019.16 AAS50510.1 - 1.5e-138 462.4 0.0 1.9e-138 462.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF3948 PF13134.1 AAS50510.1 - 6.8 6.2 6.1 22 4.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) DUF1708 PF08101.6 AAS50511.1 - 1e-140 469.2 0.1 2.6e-140 467.9 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) INO80_Ies4 PF08193.6 AAS50512.1 - 0.033 14.1 0.7 0.046 13.6 0.0 1.5 1 1 1 2 2 2 0 INO80 complex subunit Ies4 Cellulase PF00150.13 AAS50513.1 - 3e-11 43.0 1.1 7e-11 41.8 0.8 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) F-actin_cap_A PF01267.12 AAS50513.1 - 0.018 14.1 0.0 0.046 12.7 0.0 1.6 2 0 0 2 2 2 0 F-actin capping protein alpha subunit SNF2_N PF00176.18 AAS50514.1 - 9.8e-65 218.2 0.2 9.8e-65 218.2 0.1 2.7 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AAS50514.1 - 2.5e-11 43.2 0.0 6.4e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 AAS50514.1 - 2.4e-06 27.4 1.7 8e-06 25.7 1.2 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AAS50514.1 - 1.4e-05 24.7 3.0 2.9e-05 23.6 2.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AAS50514.1 - 2.6e-05 23.7 3.0 5.5e-05 22.7 2.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AAS50514.1 - 0.0001 21.9 3.4 0.00021 20.9 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AAS50514.1 - 0.00012 21.8 3.4 0.00027 20.6 2.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 AAS50514.1 - 0.0018 17.9 0.5 0.0055 16.4 0.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 AAS50514.1 - 0.054 13.0 1.7 0.24 10.9 1.2 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Cornichon PF03311.9 AAS50516.1 - 3.9e-52 175.7 11.0 4.4e-52 175.5 7.6 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.6 AAS50516.1 - 0.023 14.3 0.1 0.043 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) DUF1673 PF07895.6 AAS50516.1 - 4.2 6.8 7.3 1.5 8.2 3.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) PIN_2 PF10130.4 AAS50517.1 - 0.45 10.5 3.2 0.73 9.8 2.2 1.3 1 0 0 1 1 1 0 PIN domain RRM_1 PF00076.17 AAS50518.1 - 2.7e-39 132.6 0.0 2.4e-16 59.0 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS50518.1 - 1.4e-26 92.2 0.0 2.3e-11 43.4 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS50518.1 - 3.8e-21 74.6 0.0 1.4e-08 34.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AAS50518.1 - 0.00053 19.8 0.0 0.0034 17.2 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 AAS50518.1 - 0.0022 17.7 0.0 0.023 14.4 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 AAS50518.1 - 0.14 11.9 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 NAD_binding_7 PF13241.1 AAS50519.1 - 2.1e-22 79.2 0.0 3.3e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 AAS50519.1 - 4.1e-13 48.0 0.0 6.1e-13 47.4 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.1 AAS50519.1 - 5.2e-12 44.9 0.1 1.2e-11 43.7 0.0 1.6 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal FA_desaturase PF00487.19 AAS50520.1 - 1.7e-19 70.3 21.7 1.7e-19 70.3 15.0 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 AAS50520.1 - 1.1e-15 57.1 0.0 3.4e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain CBS PF00571.23 AAS50521.1 - 2e-20 72.2 5.8 8.3e-06 25.4 0.1 5.3 5 0 0 5 5 5 5 CBS domain Tir_receptor_C PF07489.6 AAS50521.1 - 0.12 12.0 4.0 0.24 11.1 2.8 1.5 1 1 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus UQ_con PF00179.21 AAS50523.1 - 1.3e-50 170.5 0.1 1.4e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AAS50523.1 - 7.1e-06 25.8 0.0 9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 AAS50523.1 - 0.031 13.9 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 AAS50523.1 - 0.031 14.1 0.3 0.084 12.7 0.2 1.8 1 1 0 1 1 1 0 RWD domain BCDHK_Adom3 PF10436.4 AAS50524.1 - 1.1e-36 125.8 1.6 1.8e-36 125.1 1.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 AAS50524.1 - 1e-10 41.3 0.0 4e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AAS50524.1 - 0.07 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HUN PF08729.5 AAS50525.1 - 2.7e-14 52.7 0.1 2.7e-14 52.7 0.0 2.3 2 0 0 2 2 2 1 HPC2 and ubinuclein domain Nucleoplasmin PF03066.10 AAS50525.1 - 0.41 10.1 5.5 0.71 9.3 3.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin Kinetochor_Ybp2 PF08568.5 AAS50526.1 - 6.7e-151 503.6 0.0 8.2e-151 503.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin APG12 PF04110.8 AAS50527.1 - 3e-27 94.6 0.0 4.4e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DASH_Duo1 PF08651.5 AAS50528.2 - 2.2e-28 97.6 0.3 2.2e-28 97.6 0.2 1.8 2 0 0 2 2 2 1 DASH complex subunit Duo1 DUF885 PF05960.6 AAS50528.2 - 0.0026 17.0 0.1 0.0029 16.8 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF4201 PF13870.1 AAS50528.2 - 0.0029 17.0 1.3 0.0036 16.7 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) FlgN PF05130.7 AAS50528.2 - 0.021 15.0 0.8 0.021 15.0 0.5 2.0 1 1 1 2 2 2 0 FlgN protein Allexi_40kDa PF05549.6 AAS50528.2 - 0.026 13.8 0.2 0.12 11.6 0.1 1.8 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF4618 PF15397.1 AAS50528.2 - 0.042 13.1 2.2 0.097 11.9 1.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) TPR_MLP1_2 PF07926.7 AAS50528.2 - 0.047 13.4 0.7 0.072 12.8 0.4 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein AIP3 PF03915.8 AAS50528.2 - 0.07 12.0 0.6 0.11 11.3 0.4 1.3 1 1 0 1 1 1 0 Actin interacting protein 3 DASH_Dam1 PF08653.5 AAS50528.2 - 0.099 12.4 0.1 0.59 9.9 0.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Dam1 DASH_Dad2 PF08654.5 AAS50528.2 - 0.13 12.2 1.1 0.83 9.6 0.2 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad2 FUSC PF04632.7 AAS50528.2 - 0.35 9.2 2.1 0.42 9.0 1.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CPSase_L_D2 PF02786.12 AAS50529.2 - 9.1e-84 279.9 0.5 1.4e-83 279.3 0.4 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 AAS50529.2 - 9e-66 221.0 0.0 2e-65 219.8 0.0 1.6 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 AAS50529.2 - 5.6e-35 119.7 0.0 1.3e-34 118.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 AAS50529.2 - 4.2e-30 103.8 0.0 2.2e-29 101.5 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 AAS50529.2 - 4.6e-26 91.9 0.5 1.3e-25 90.5 0.0 1.9 2 0 0 2 2 2 1 HMGL-like Biotin_lipoyl PF00364.17 AAS50529.2 - 2.9e-19 68.4 3.5 2.9e-19 68.4 2.5 2.3 3 0 0 3 3 3 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 AAS50529.2 - 7.2e-18 64.9 0.3 1.4e-17 63.9 0.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AAS50529.2 - 8.8e-18 64.1 0.0 2.9e-17 62.4 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 AAS50529.2 - 5.5e-09 35.7 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 AAS50529.2 - 1.6e-08 34.0 3.5 0.00038 20.0 0.2 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 AAS50529.2 - 3.1e-08 33.1 0.1 7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 AAS50529.2 - 4.6e-07 29.5 0.1 9.1e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 AAS50529.2 - 1.6e-05 24.8 0.0 5.1e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 AAS50529.2 - 0.00026 20.4 1.2 0.22 10.7 0.1 2.5 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_2 PF12700.2 AAS50529.2 - 0.0017 17.5 0.5 0.81 8.7 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 AAS50529.2 - 0.0025 18.1 3.2 2.6 8.4 0.1 3.4 3 0 0 3 3 3 2 HlyD family secretion protein RnfC_N PF13375.1 AAS50529.2 - 0.041 13.6 2.7 0.32 10.7 0.4 2.9 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain MF_alpha_N PF05436.6 AAS50530.1 - 1.8e-11 43.5 0.0 2.1e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus Med31 PF05669.7 AAS50531.1 - 5.9e-34 115.9 0.4 6.6e-34 115.7 0.3 1.1 1 0 0 1 1 1 1 SOH1 Scs3p PF10261.4 AAS50532.1 - 6.3e-78 261.1 1.4 1.4e-77 259.9 0.9 1.5 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Acatn PF13000.2 AAS50533.2 - 5.3e-200 665.5 14.6 6.1e-200 665.3 10.1 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Transket_pyr PF02779.19 AAS50534.1 - 1.2e-47 161.7 0.0 4.5e-47 159.8 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AAS50534.1 - 2.1e-36 124.5 0.1 4.6e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain AMP-binding PF00501.23 AAS50535.1 - 1.2e-78 264.3 0.0 1.5e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AAS50535.1 - 1.7e-16 60.9 0.7 5.8e-16 59.2 0.2 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Tyr-DNA_phospho PF06087.7 AAS50536.1 - 1.3e-116 389.8 0.0 1.6e-116 389.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase MTHFR PF02219.12 AAS50537.2 - 3.7e-114 380.6 0.0 5e-114 380.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Methyltransf_11 PF08241.7 AAS50538.1 - 0.046 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 AAS50538.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain GIY-YIG PF01541.19 AAS50539.1 - 2.4e-08 34.2 0.0 5.6e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain Tmpp129 PF10272.4 AAS50539.1 - 0.034 12.8 0.8 0.044 12.5 0.6 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Baculo_p47 PF05112.7 AAS50539.1 - 0.053 12.9 0.3 0.078 12.3 0.2 1.2 1 0 0 1 1 1 0 Baculovirus P47 protein zf-C2H2_2 PF12756.2 AAS50539.1 - 0.11 12.6 4.3 0.96 9.5 0.4 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FANCL_C PF11793.3 AAS50539.1 - 0.41 10.6 6.8 0.52 10.3 3.9 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.1 AAS50539.1 - 5.7 6.8 7.3 44 4.0 4.3 2.3 1 1 1 2 2 2 0 Ring finger domain Glyco_hydro_31 PF01055.21 AAS50540.1 - 1.6e-135 452.3 0.2 2.3e-135 451.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 AAS50540.1 - 9.1e-22 76.6 0.0 2.9e-21 75.0 0.0 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like GATA PF00320.22 AAS50541.1 - 7.2e-10 38.0 4.3 1.3e-09 37.2 3.0 1.4 1 0 0 1 1 1 1 GATA zinc finger Mon1 PF03164.9 AAS50542.2 - 2.9e-101 339.0 0.1 3.9e-101 338.6 0.1 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Tape_meas_lam_C PF09718.5 AAS50543.1 - 0.035 14.0 2.7 1.1 9.2 0.0 2.3 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) EspB PF05802.6 AAS50543.1 - 0.27 10.1 3.9 0.43 9.4 2.7 1.3 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF883 PF05957.8 AAS50543.1 - 2.6 8.4 8.7 0.8 10.1 3.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Ribosomal_S5 PF00333.15 AAS50544.1 - 2e-28 97.9 3.6 2e-28 97.9 2.5 2.4 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 AAS50544.1 - 2.4e-21 74.8 0.0 4.2e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain E3_binding PF02817.12 AAS50544.1 - 0.1 12.2 1.1 0.37 10.4 0.0 2.3 2 0 0 2 2 2 0 e3 binding domain Nab2 PF11517.3 AAS50545.1 - 1.2e-52 176.4 0.3 1.9e-52 175.8 0.2 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.1 AAS50545.1 - 4.9e-09 35.8 62.4 9.5e-05 22.2 2.9 6.7 6 1 0 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type DUF2508 PF10704.4 AAS50545.1 - 0.014 15.5 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) HA2 PF04408.18 AAS50547.1 - 5.6e-27 93.7 0.0 1.2e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AAS50547.1 - 1e-24 86.5 0.0 2.6e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AAS50547.1 - 1.2e-13 50.6 0.0 2.7e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AAS50547.1 - 4.7e-09 35.9 0.2 8.1e-09 35.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AAS50547.1 - 6.9e-06 26.2 0.0 3.4e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 AAS50547.1 - 1.5e-05 24.5 0.1 3.5e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 AAS50547.1 - 0.00031 20.6 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 AAS50547.1 - 0.00041 20.1 0.2 0.00082 19.1 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_23 PF13476.1 AAS50547.1 - 0.0073 16.6 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AAS50547.1 - 0.02 13.8 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 AAS50547.1 - 0.021 14.4 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 AAS50547.1 - 0.071 12.3 0.0 0.26 10.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.17 AAS50547.1 - 0.093 11.5 0.0 0.31 9.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.1 AAS50547.1 - 0.098 12.2 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC1 PF03109.11 AAS50548.1 - 9.8e-35 119.1 0.0 2.6e-34 117.7 0.0 1.8 2 0 0 2 2 2 1 ABC1 family La PF05383.12 AAS50549.1 - 3.5e-15 55.5 0.0 5.6e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 La domain Mannosyl_trans3 PF11051.3 AAS50550.1 - 1.6e-65 221.1 0.0 2.2e-65 220.7 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative XH PF03469.9 AAS50550.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.1 3 0 0 3 3 3 0 XH domain IPK PF03770.11 AAS50551.1 - 5.7e-50 169.6 0.4 1.8e-49 168.0 0.0 2.0 2 0 0 2 2 2 1 Inositol polyphosphate kinase DASH_Dad1 PF08649.5 AAS50552.1 - 9.6e-31 105.2 1.3 1.2e-30 104.9 0.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Peptidase_M57 PF12388.3 AAS50552.1 - 0.068 12.4 0.0 0.081 12.2 0.0 1.1 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase PNPOx_C PF10590.4 AAS50553.1 - 5.1e-21 73.9 2.9 1.1e-20 72.8 2.0 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 AAS50553.1 - 1.5e-13 50.5 0.0 2.3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 AAS50553.1 - 0.025 14.8 0.1 0.057 13.7 0.1 1.7 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase WAPL PF07814.8 AAS50554.1 - 0.0017 17.1 3.4 0.73 8.5 0.0 2.3 2 0 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin Sld5 PF05916.6 AAS50555.1 - 2.7e-10 40.4 0.2 4.3e-10 39.8 0.2 1.4 1 0 0 1 1 1 1 GINS complex protein PIF1 PF05970.9 AAS50555.1 - 0.0053 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase DUF3016 PF11454.3 AAS50555.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3016) Methyltransf_10 PF05971.7 AAS50556.1 - 6.9e-40 137.0 0.0 8.6e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 AAS50556.1 - 8.5e-05 21.9 0.0 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 AAS50556.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS50556.1 - 0.007 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 AAS50556.1 - 0.011 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.2 AAS50556.1 - 0.033 14.7 0.0 0.073 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 AAS50556.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 AAS50557.1 - 7.5e-13 48.3 0.0 1.8e-12 47.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AAS50557.1 - 2.2e-11 43.4 0.0 3.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 AAS50557.1 - 3.5e-11 43.6 0.0 6.6e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AAS50557.1 - 1.5e-10 41.0 0.0 3.3e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AAS50557.1 - 2.4e-08 34.3 0.0 8.5e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AAS50557.1 - 4.8e-07 29.6 0.0 8.6e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AAS50557.1 - 6.1e-07 28.7 0.0 8.5e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 AAS50557.1 - 1.4e-06 27.8 0.1 2.3e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 AAS50557.1 - 1.9e-06 26.8 0.1 2.5e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 AAS50557.1 - 1.4e-05 25.4 0.0 3.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 AAS50557.1 - 0.00016 21.1 0.2 0.00025 20.5 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 AAS50557.1 - 0.00022 21.6 0.0 0.00058 20.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.14 AAS50557.1 - 0.00039 20.4 0.0 0.00088 19.3 0.0 1.5 2 0 0 2 2 1 1 FtsJ-like methyltransferase PRMT5 PF05185.11 AAS50557.1 - 0.00084 18.3 0.0 0.00098 18.1 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PCMT PF01135.14 AAS50557.1 - 0.0028 17.2 0.1 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 AAS50557.1 - 0.0057 16.2 0.1 0.0088 15.6 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.13 AAS50557.1 - 0.0097 15.0 0.3 0.072 12.1 0.2 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 AAS50557.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family TehB PF03848.9 AAS50557.1 - 0.016 14.3 0.1 0.028 13.5 0.1 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB UPF0020 PF01170.13 AAS50557.1 - 0.027 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 AAS50557.1 - 0.039 12.9 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.1 AAS50557.1 - 0.047 13.3 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 AAS50557.1 - 0.087 13.6 0.0 0.16 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 AAS50557.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ribosomal_L4 PF00573.17 AAS50558.1 - 7.8e-47 159.1 1.4 1.3e-46 158.4 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 AAS50558.1 - 2.6e-31 107.3 4.1 1.2e-30 105.1 0.7 2.6 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain MFS_1 PF07690.11 AAS50559.1 - 1.8e-30 105.8 20.0 1.8e-30 105.8 13.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AAS50559.1 - 1.1e-24 86.8 21.7 6.2e-24 84.3 14.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter SET PF00856.23 AAS50560.1 - 7.7e-09 36.0 0.0 1.4e-07 31.9 0.0 2.3 1 1 0 1 1 1 1 SET domain MFS_1 PF07690.11 AAS50561.1 - 1.2e-27 96.5 17.7 2e-27 95.8 12.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AAS50561.1 - 1.1e-25 90.1 19.2 3e-25 88.7 13.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 AAS50561.1 - 0.0042 16.8 1.8 3.1 7.6 0.0 3.6 3 0 0 3 3 3 2 MFS_1 like family DUF1228 PF06779.9 AAS50561.1 - 0.036 14.0 2.6 0.054 13.5 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) MFS_3 PF05977.8 AAS50561.1 - 0.54 8.3 6.8 0.1 10.7 0.4 2.4 3 0 0 3 3 3 0 Transmembrane secretion effector Aldo_ket_red PF00248.16 AAS50562.2 - 1.8e-49 168.0 0.0 2.3e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ATG2_CAD PF13329.1 AAS50563.2 - 1.2e-38 132.1 0.7 1.2e-38 132.1 0.5 3.2 4 0 0 4 4 4 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 AAS50563.2 - 2.2e-29 101.4 0.5 5.1e-29 100.3 0.4 1.7 1 0 0 1 1 1 1 ATG C terminal domain RhoGAP PF00620.22 AAS50564.2 - 2.6e-34 118.0 0.5 8e-34 116.4 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 AAS50564.2 - 2.6e-25 88.2 60.2 9.9e-09 35.1 4.0 4.5 4 0 0 4 4 4 4 LIM domain G6PD_C PF02781.11 AAS50565.1 - 3.3e-130 433.2 0.0 4.5e-130 432.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 AAS50565.1 - 2.5e-65 220.1 0.1 4.5e-65 219.3 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Fe_hyd_lg_C PF02906.9 AAS50566.1 - 7.4e-73 245.2 0.0 9.5e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Peptidase_C1_2 PF03051.10 AAS50567.1 - 2.8e-162 540.2 0.0 3.2e-162 540.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 AAS50567.1 - 4.6e-09 36.4 0.0 0.00058 19.7 0.1 2.2 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_S8 PF00082.17 AAS50568.2 - 1.1e-55 188.7 0.3 1.6e-55 188.2 0.2 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 AAS50568.2 - 2.8e-23 81.5 0.7 6.1e-23 80.4 0.5 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF1180 PF06679.7 AAS50568.2 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Herpes_gE PF02480.11 AAS50568.2 - 0.014 13.7 0.0 0.024 12.9 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3188 PF11384.3 AAS50568.2 - 0.074 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Med16 PF11635.3 AAS50569.2 - 4.9e-205 682.8 1.7 5.8e-205 682.5 1.2 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 SPAN-X PF07458.7 AAS50569.2 - 0.15 12.3 0.2 0.29 11.3 0.2 1.4 1 0 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome Globin PF00042.17 AAS50570.1 - 1.5e-05 25.2 0.0 4.1e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Globin IER PF05760.7 AAS50570.1 - 4.1 7.2 7.2 0.74 9.6 0.1 2.2 2 0 0 2 2 2 0 Immediate early response protein (IER) DUF917 PF06032.7 AAS50571.1 - 0.19 10.2 0.0 0.3 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) EXOSC1 PF10447.4 AAS50572.1 - 1.9e-32 111.0 0.1 3.1e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 CRAL_TRIO PF00650.15 AAS50573.1 - 1.8e-40 138.0 0.0 2.6e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AAS50573.1 - 9.8e-12 44.8 0.2 2.7e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AAS50573.1 - 0.0011 18.9 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Elongin_A PF06881.6 AAS50574.1 - 1.2e-22 80.3 8.7 6e-21 74.8 0.2 2.2 1 1 1 2 2 2 2 RNA polymerase II transcription factor SIII (Elongin) subunit A GST_C PF00043.20 AAS50576.1 - 2.6e-19 68.9 0.0 3.9e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AAS50576.1 - 2.3e-16 59.7 0.0 4.4e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AAS50576.1 - 1e-10 41.4 0.0 6.6e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 AAS50576.1 - 5.1e-10 39.4 0.0 1.6e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AAS50576.1 - 0.00085 19.1 0.1 0.0027 17.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DnaJ PF00226.26 AAS50577.1 - 1.3e-24 85.6 0.3 5.4e-24 83.7 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_2 PF12756.2 AAS50577.1 - 9.7e-08 32.0 4.0 0.0057 16.7 0.5 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 AAS50577.1 - 3.8e-07 30.0 2.5 3.8e-07 30.0 1.8 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AAS50577.1 - 0.00045 20.3 2.7 0.00045 20.3 1.9 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 AAS50577.1 - 0.0012 19.0 11.1 0.13 12.6 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 AAS50577.1 - 0.0064 16.3 8.0 0.057 13.3 1.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 AAS50577.1 - 0.011 15.9 8.2 0.28 11.5 0.6 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger TFIIS_C PF01096.13 AAS50577.1 - 0.11 12.0 0.9 0.4 10.3 0.0 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) AP-5_subunit_s1 PF15001.1 AAS50577.1 - 3 7.7 8.2 0.85 9.5 2.9 2.1 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 SID PF11778.3 AAS50578.2 - 9.3e-58 194.0 6.6 9.3e-58 194.0 4.6 3.3 4 0 0 4 4 4 1 Septation initiation Myosin_tail_1 PF01576.14 AAS50578.2 - 0.0047 14.7 99.0 0.082 10.6 17.2 2.8 2 1 0 2 2 2 2 Myosin tail AAA_13 PF13166.1 AAS50578.2 - 0.0051 15.3 82.5 0.0037 15.8 24.0 3.1 2 1 1 3 3 3 2 AAA domain DSX_dimer PF08828.5 AAS50578.2 - 0.0052 16.3 0.3 0.02 14.4 0.2 2.1 1 0 0 1 1 1 1 Doublesex dimerisation domain Tup_N PF08581.5 AAS50578.2 - 0.0059 16.7 1.6 0.0059 16.7 1.1 8.3 6 2 2 8 8 8 2 Tup N-terminal Reo_sigmaC PF04582.7 AAS50578.2 - 0.034 13.3 40.2 0.16 11.1 1.4 5.2 2 2 3 6 6 6 0 Reovirus sigma C capsid protein G-patch PF01585.18 AAS50579.1 - 2.5e-12 46.3 0.6 4.7e-12 45.5 0.4 1.5 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 AAS50579.1 - 0.06 13.0 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 R3H domain Peptidase_C54 PF03416.14 AAS50580.1 - 7.4e-87 291.0 0.0 1e-86 290.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 Ssu72 PF04722.8 AAS50581.1 - 2.5e-88 294.5 0.0 3e-88 294.2 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein POP1 PF06978.6 AAS50584.1 - 4.4e-68 228.6 11.3 4.4e-68 228.6 7.8 2.3 2 1 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 AAS50584.1 - 5.1e-32 109.5 0.7 1.1e-31 108.4 0.5 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain DUF1389 PF07146.6 AAS50584.1 - 0.024 13.6 0.1 0.045 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) SRA1 PF07304.6 AAS50584.1 - 0.078 12.7 3.2 4 7.1 0.1 2.5 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Adenylsucc_synt PF00709.16 AAS50585.2 - 2.5e-163 543.6 0.0 2.8e-163 543.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Glyco_transf_22 PF03901.12 AAS50586.1 - 7e-88 295.4 27.1 9e-88 295.0 18.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Hydrolase_6 PF13344.1 AAS50587.1 - 8.4e-28 96.2 0.0 2.2e-27 94.8 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AAS50587.1 - 1.7e-14 53.2 0.0 4e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 AAS50587.1 - 1e-13 52.1 0.0 1.6e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AAS50587.1 - 5.4e-07 30.0 0.0 0.015 15.5 0.1 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase MgsA_C PF12002.3 AAS50588.1 - 4.3e-53 179.4 0.1 8.4e-53 178.4 0.1 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 AAS50588.1 - 2.7e-15 56.7 0.0 6e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AAS50588.1 - 1.3e-13 50.5 0.0 6.8e-13 48.2 0.0 2.0 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AAS50588.1 - 1.2e-07 31.9 0.1 2.9e-05 24.1 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 AAS50588.1 - 7.9e-07 28.8 0.2 3e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AAS50588.1 - 2.1e-06 27.9 0.3 0.00012 22.1 0.2 3.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AAS50588.1 - 3.8e-06 26.8 0.0 8.2e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 AAS50588.1 - 0.00013 21.4 0.0 0.00073 19.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 AAS50588.1 - 0.00022 21.5 0.0 0.00082 19.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 AAS50588.1 - 0.00026 20.2 0.1 0.056 12.6 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 AAS50588.1 - 0.00041 19.8 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 AAS50588.1 - 0.00066 19.6 0.0 0.0033 17.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 AAS50588.1 - 0.002 17.1 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 AAS50588.1 - 0.0029 17.1 0.0 0.017 14.6 0.0 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 AAS50588.1 - 0.0031 18.3 0.0 0.012 16.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 AAS50588.1 - 0.0039 16.8 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 AAS50588.1 - 0.0049 16.4 0.0 0.01 15.4 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 AAS50588.1 - 0.0061 16.2 0.0 0.0098 15.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein ABC_tran PF00005.22 AAS50588.1 - 0.0078 16.5 0.2 0.029 14.6 0.0 2.1 2 1 1 3 3 2 1 ABC transporter AAA_30 PF13604.1 AAS50588.1 - 0.0083 15.7 0.0 0.022 14.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AAS50588.1 - 0.012 15.2 0.1 0.18 11.5 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 AAS50588.1 - 0.016 15.3 0.0 0.061 13.5 0.0 2.1 2 0 0 2 2 1 0 RNA helicase Sigma54_activ_2 PF14532.1 AAS50588.1 - 0.02 14.9 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain cobW PF02492.14 AAS50588.1 - 0.02 14.3 0.1 2.3 7.6 0.0 2.3 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.10 AAS50588.1 - 0.036 13.8 0.0 0.93 9.2 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Sgf11 PF08209.6 AAS50588.1 - 0.037 13.3 0.2 0.074 12.3 0.2 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Arch_ATPase PF01637.13 AAS50588.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 AAS50588.1 - 0.079 12.3 1.7 2.8 7.2 0.0 3.2 2 1 1 3 3 3 0 AAA-like domain AAA_28 PF13521.1 AAS50588.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-C2HC_2 PF13913.1 AAS50588.1 - 0.13 11.9 0.2 0.23 11.1 0.2 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type MMR_HSR1 PF01926.18 AAS50588.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Hpt PF01627.18 AAS50589.1 - 1.4e-13 50.6 1.0 1.8e-13 50.2 0.7 1.1 1 0 0 1 1 1 1 Hpt domain Glyco_hydro_10 PF00331.15 AAS50589.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 IpaB_EvcA PF03278.8 AAS50589.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 IpaB/EvcA family Metallophos PF00149.23 AAS50590.1 - 3.8e-09 36.2 0.8 6.8e-09 35.4 0.6 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AAS50590.1 - 0.00018 21.4 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.6 AAS50590.1 - 0.013 13.5 0.1 0.81 7.6 0.0 2.0 1 1 1 2 2 2 0 Firmicute fructose-1,6-bisphosphatase Rap1-DNA-bind PF09197.5 AAS50591.1 - 8.4e-47 158.0 8.3 1e-42 144.9 0.8 3.5 3 0 0 3 3 3 2 Rap1, DNA-binding Rap1_C PF11626.3 AAS50591.1 - 3.6e-24 84.4 0.0 2.1e-22 78.7 0.0 3.2 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.26 AAS50591.1 - 2.9e-10 40.0 0.0 3.3e-08 33.4 0.0 3.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 AAS50591.1 - 1.1e-07 31.5 0.5 9.6e-05 22.1 0.0 2.8 2 0 0 2 2 2 2 Rap1 Myb domain BRCT PF00533.21 AAS50591.1 - 0.00034 20.7 0.6 0.0012 18.9 0.0 2.3 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Myb_DNA-bind_6 PF13921.1 AAS50591.1 - 0.0036 17.3 1.1 0.16 12.0 0.0 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain RabGAP-TBC PF00566.13 AAS50592.2 - 2.9e-29 102.0 25.2 1.6e-27 96.3 7.7 2.8 2 1 0 3 3 3 2 Rab-GTPase-TBC domain PAPA-1 PF04795.7 AAS50593.1 - 9.9e-16 58.2 6.5 9.9e-16 58.2 4.5 2.4 2 1 0 2 2 2 1 PAPA-1-like conserved region LIM_bind PF01803.11 AAS50594.1 - 3.4e-61 206.4 0.0 3.4e-61 206.4 0.0 1.5 2 0 0 2 2 2 1 LIM-domain binding protein Z1 PF10593.4 AAS50595.1 - 0.064 12.4 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Z1 domain Neugrin PF06413.6 AAS50596.1 - 1e-06 28.7 0.4 1e-06 28.7 0.3 1.6 2 0 0 2 2 2 1 Neugrin DUF1967 PF09269.6 AAS50596.1 - 0.00037 20.0 0.1 0.0015 18.1 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF1967) Sigma70_r4 PF04545.11 AAS50596.1 - 0.001 18.3 0.0 0.0025 17.0 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_11 PF08279.7 AAS50596.1 - 0.0044 16.6 0.1 0.021 14.4 0.0 2.2 2 0 0 2 2 2 1 HTH domain DUF3144 PF11342.3 AAS50596.1 - 0.015 15.3 0.1 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) HTH_32 PF13565.1 AAS50596.1 - 0.03 15.1 3.3 0.12 13.1 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_7 PF02796.10 AAS50596.1 - 0.057 13.2 0.2 0.18 11.7 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HSP70 PF00012.15 AAS50597.1 - 3.8e-239 794.6 7.9 4.2e-239 794.4 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AAS50597.1 - 9.2e-18 63.9 1.4 2.7e-16 59.1 0.5 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 AAS50597.1 - 0.00017 21.2 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain EAP30 PF04157.11 AAS50597.1 - 0.034 13.3 0.8 0.067 12.3 0.6 1.5 1 0 0 1 1 1 0 EAP30/Vps36 family DUF2984 PF11203.3 AAS50597.1 - 0.12 12.5 1.6 0.2 11.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) Flagellin_N PF00669.15 AAS50597.1 - 0.23 11.2 2.9 0.54 10.0 2.0 1.6 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region KH_1 PF00013.24 AAS50598.1 - 0.00065 19.2 0.0 0.0015 18.1 0.0 1.6 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 AAS50598.1 - 0.022 14.4 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 KH domain Y_phosphatase PF00102.22 AAS50599.1 - 5e-55 186.3 0.3 8.9e-54 182.2 0.2 2.0 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 AAS50599.1 - 0.0013 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 AAS50599.1 - 0.0045 16.5 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 AAS50599.1 - 0.028 14.4 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate FUSC_2 PF13515.1 AAS50600.2 - 3.5e-17 62.5 6.2 3.5e-17 62.5 4.3 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF2422 PF10337.4 AAS50600.2 - 0.0094 14.7 5.0 0.24 10.1 2.1 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF2422) Ost4 PF10215.4 AAS50601.1 - 2.7e-18 65.1 1.5 3.1e-18 64.9 1.0 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase CaKB PF03185.10 AAS50601.1 - 0.089 12.1 0.1 0.089 12.1 0.1 1.0 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit DUF2697 PF10906.3 AAS50602.1 - 4.7e-30 103.4 0.1 5.5e-30 103.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2697) Abi PF02517.11 AAS50602.1 - 0.13 12.3 0.2 0.13 12.3 0.1 1.3 1 1 0 1 1 1 0 CAAX protease self-immunity VID27 PF08553.5 AAS50603.1 - 0 1082.3 2.0 0 1082.1 1.4 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein RIO1 PF01163.17 AAS50605.1 - 3.7e-43 147.1 0.6 5.8e-43 146.4 0.4 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 AAS50605.1 - 2.2e-30 104.5 0.2 6e-30 103.1 0.1 1.8 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 AAS50605.1 - 1.8e-08 34.4 1.9 0.00014 21.7 0.0 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 AAS50605.1 - 9.3e-05 21.6 0.1 0.00019 20.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 AAS50605.1 - 0.00041 19.4 0.1 0.014 14.4 0.1 2.5 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SGT1 PF07093.6 AAS50605.1 - 0.0024 16.3 2.0 0.0028 16.0 1.4 1.2 1 0 0 1 1 1 1 SGT1 protein FAM178 PF14816.1 AAS50605.1 - 0.63 8.6 5.4 0.91 8.1 3.7 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 Nop14 PF04147.7 AAS50605.1 - 0.94 7.3 11.9 1.2 6.9 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 AAS50605.1 - 1.5 7.9 7.1 2.2 7.4 4.9 1.2 1 0 0 1 1 1 0 NOA36 protein Astro_capsid PF03115.9 AAS50605.1 - 8.1 4.5 6.6 12 3.9 4.6 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Rtt106 PF08512.7 AAS50606.1 - 2.2e-29 101.2 1.1 4.2e-29 100.3 0.8 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like ArfGap PF01412.13 AAS50607.1 - 1.8e-35 121.2 0.0 4.5e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf adh_short_C2 PF13561.1 AAS50608.1 - 2.4e-24 86.4 0.1 3e-24 86.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AAS50608.1 - 2.4e-19 69.8 8.4 3.8e-19 69.2 5.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AAS50608.1 - 7e-11 42.1 4.8 1.1e-10 41.5 3.3 1.2 1 0 0 1 1 1 1 KR domain SMK-1 PF04802.10 AAS50609.2 - 4.8e-64 215.4 6.6 4.8e-64 215.4 4.6 2.1 2 1 0 2 2 2 1 Component of IIS longevity pathway SMK-1 WH1 PF00568.18 AAS50609.2 - 0.003 17.2 0.0 0.064 12.9 0.0 2.3 2 0 0 2 2 2 1 WH1 domain DUF772 PF05598.6 AAS50609.2 - 0.0068 16.2 0.1 0.051 13.4 0.0 2.3 2 0 0 2 2 2 1 Transposase domain (DUF772) YjeF_N PF03853.10 AAS50610.1 - 4.3e-39 133.8 0.0 5.3e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Septin PF00735.13 AAS50612.1 - 3e-74 249.5 2.0 4.1e-73 245.8 0.0 2.8 2 1 0 2 2 2 1 Septin AAA_33 PF13671.1 AAS50612.1 - 5.4e-05 23.0 0.1 0.00053 19.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AAS50612.1 - 0.00033 20.8 0.0 0.002 18.2 0.0 2.4 2 1 0 2 2 1 1 AAA domain GTP_EFTU PF00009.22 AAS50612.1 - 0.00055 19.4 0.2 0.0023 17.3 0.0 2.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AAS50612.1 - 0.00057 19.8 0.0 0.0029 17.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 AAS50612.1 - 0.00058 19.8 0.2 0.0038 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 AAS50612.1 - 0.00075 20.3 0.1 0.0042 17.9 0.0 2.3 2 1 1 3 3 1 1 AAA domain FtsK_SpoIIIE PF01580.13 AAS50612.1 - 0.0018 17.8 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_5 PF07728.9 AAS50612.1 - 0.0024 17.6 0.0 0.0066 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 AAS50612.1 - 0.0027 17.3 0.0 0.0081 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AAS50612.1 - 0.0027 18.0 0.0 0.016 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 AAS50612.1 - 0.0032 17.6 0.2 0.011 15.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AIG1 PF04548.11 AAS50612.1 - 0.0036 16.4 1.3 0.024 13.7 0.0 2.4 2 0 0 2 2 2 1 AIG1 family RNA_helicase PF00910.17 AAS50612.1 - 0.01 15.9 0.0 0.057 13.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Sigma54_activat PF00158.21 AAS50612.1 - 0.011 15.2 0.0 0.032 13.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 AAS50612.1 - 0.015 14.7 0.0 0.057 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 AAS50612.1 - 0.023 14.9 0.7 0.43 10.8 0.0 2.6 3 0 0 3 3 2 0 ABC transporter DUF258 PF03193.11 AAS50612.1 - 0.024 13.8 0.0 0.058 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 AAS50612.1 - 0.04 13.6 0.4 0.12 12.1 0.0 2.0 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 AAS50612.1 - 0.048 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Pox_A32 PF04665.7 AAS50612.1 - 0.049 12.9 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_32 PF13654.1 AAS50612.1 - 0.071 11.7 4.3 2.4 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 AAS50612.1 - 0.08 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AAS50612.1 - 0.083 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 AAS50612.1 - 0.18 11.7 0.9 0.26 11.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain RRM_1 PF00076.17 AAS50613.1 - 1.7e-16 59.6 0.0 2.9e-15 55.6 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS50613.1 - 2.6e-09 36.9 0.0 1.2e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) GAGA_bind PF06217.7 AAS50613.1 - 0.14 12.1 23.1 0.32 10.9 16.0 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family AUX_IAA PF02309.11 AAS50613.1 - 5.9 6.5 20.1 15 5.2 13.9 1.7 1 0 0 1 1 1 0 AUX/IAA family SUR7 PF06687.7 AAS50615.2 - 3.9e-36 124.6 9.6 5.2e-36 124.1 6.6 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF2162 PF09930.4 AAS50615.2 - 0.0093 15.1 0.7 0.015 14.4 0.5 1.3 1 0 0 1 1 1 1 Predicted transporter (DUF2162) DUF3328 PF11807.3 AAS50615.2 - 0.027 14.1 1.0 0.12 12.0 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) Fig1 PF12351.3 AAS50615.2 - 0.78 9.5 8.6 1.5 8.6 6.0 1.4 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Wzy_C PF04932.10 AAS50615.2 - 1.1 8.9 6.3 2.2 8.0 3.1 2.3 2 1 0 2 2 2 0 O-Antigen ligase DUF3784 PF12650.2 AAS50615.2 - 2.3 8.2 8.3 0.58 10.1 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) POT1 PF02765.12 AAS50616.1 - 3.6e-16 59.3 0.0 8e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Chitin_synth_1 PF01644.12 AAS50618.2 - 9e-73 243.4 0.1 1.4e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 AAS50618.2 - 6.1e-26 89.9 2.0 7.9e-26 89.5 0.4 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 AAS50618.2 - 3.1e-16 58.8 10.5 7.3e-15 54.3 0.1 2.6 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 AAS50618.2 - 4e-11 42.9 8.4 3.1e-10 40.0 5.8 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AAS50618.2 - 4.6e-10 39.6 0.0 4e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AAS50618.2 - 0.012 15.2 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 AAS50618.2 - 0.093 12.0 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Tyr_Deacylase PF02580.11 AAS50619.2 - 9.3e-50 168.3 0.0 1e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase GATase_4 PF13230.1 AAS50620.1 - 1.2e-18 66.7 0.1 5.4e-17 61.3 0.1 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 AAS50620.1 - 4.5e-11 42.8 0.0 1.1e-10 41.6 0.0 1.6 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 AAS50620.1 - 1.6e-10 40.2 0.0 1.1e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 AAS50620.1 - 0.0032 17.2 0.0 0.007 16.0 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain Arm PF00514.18 AAS50621.1 - 1.6e-87 284.6 16.7 6.4e-14 51.1 0.1 8.6 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 AAS50621.1 - 5.3e-24 84.2 9.0 8.2e-24 83.5 5.7 1.7 2 0 0 2 2 2 1 Importin beta binding domain HEAT_2 PF13646.1 AAS50621.1 - 2.8e-22 78.7 0.2 1.3e-06 28.5 0.0 5.7 1 1 5 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 AAS50621.1 - 1.2e-18 67.0 7.4 2.7e-05 24.5 0.0 6.4 5 3 3 8 8 7 4 HEAT-like repeat HEAT PF02985.17 AAS50621.1 - 6.3e-13 47.6 1.2 0.012 15.6 0.0 6.7 7 0 0 7 7 7 2 HEAT repeat Arm_2 PF04826.8 AAS50621.1 - 1.3e-07 31.0 1.2 1.4 7.9 0.0 4.7 2 1 5 7 7 7 5 Armadillo-like Adaptin_N PF01602.15 AAS50621.1 - 3.1e-05 22.4 0.7 0.00083 17.8 0.3 2.8 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 AAS50621.1 - 5.8e-05 22.9 0.1 0.56 10.1 0.0 4.4 2 1 4 6 6 6 2 V-ATPase subunit H RICTOR_V PF14668.1 AAS50621.1 - 0.00014 21.7 4.6 3.7 7.5 0.0 5.5 3 3 4 7 7 7 3 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 AAS50621.1 - 0.0002 19.7 0.8 0.0043 15.3 0.1 2.8 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit FAST_1 PF06743.10 AAS50621.1 - 0.025 14.2 1.0 0.98 9.1 0.0 3.1 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 1 CCDC-167 PF15188.1 AAS50622.1 - 0.017 15.0 0.8 1.6 8.7 0.1 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Tim17 PF02466.14 AAS50623.1 - 1.3e-48 164.2 4.9 1.8e-48 163.8 3.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DLH PF01738.13 AAS50623.1 - 0.11 11.8 1.4 0.2 10.8 0.0 1.9 2 1 0 2 2 2 0 Dienelactone hydrolase family JAB PF01398.16 AAS50625.1 - 5.7e-25 87.2 0.0 9.7e-25 86.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 AAS50625.1 - 2.8e-07 30.0 0.0 5.5e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 AAS50625.1 - 0.089 12.2 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) UCH PF00443.24 AAS50626.1 - 7.4e-57 192.4 0.5 1.3e-56 191.6 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AAS50626.1 - 4.4e-17 62.4 0.0 7.7e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_RNApol_7kD PF03604.8 AAS50626.1 - 0.14 11.6 1.8 7.8 6.0 0.1 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_L11_N PF03946.9 AAS50627.1 - 2.9e-27 93.9 0.2 4.1e-27 93.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 AAS50627.1 - 1.1e-24 86.3 0.2 1.8e-24 85.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Pkinase PF00069.20 AAS50628.3 - 8e-61 205.4 0.0 1.1e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS50628.3 - 2e-22 79.5 0.0 4.8e-22 78.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 AAS50628.3 - 0.016 14.6 0.0 0.038 13.3 0.0 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 AAS50628.3 - 0.28 10.8 0.1 0.49 10.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM_1 PF00076.17 AAS50629.1 - 1.2e-05 24.8 0.0 2.7e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS50629.1 - 0.00015 21.6 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS50629.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 AAS50630.1 - 1.4e-07 31.1 0.3 0.015 15.1 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1513 PF07433.6 AAS50630.1 - 0.044 12.6 0.2 0.1 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) PQQ_2 PF13360.1 AAS50630.1 - 0.048 13.1 0.2 0.19 11.1 0.1 2.0 2 0 0 2 2 2 0 PQQ-like domain adh_short PF00106.20 AAS50631.2 - 1.4e-10 41.3 0.0 7.7e-10 38.9 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AAS50631.2 - 4.6e-08 32.9 0.0 9.2e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Ras PF00071.17 AAS50632.1 - 1.3e-47 161.2 0.0 1.7e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS50632.1 - 3.6e-14 53.2 0.0 1.3e-13 51.5 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS50632.1 - 2.3e-07 30.2 0.0 4.7e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AAS50632.1 - 2.9e-05 23.6 0.0 9e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AAS50632.1 - 0.034 13.2 0.0 0.092 11.8 0.0 1.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AAS50632.1 - 0.063 13.2 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ribosomal_S3_C PF00189.15 AAS50633.2 - 1.8e-16 60.1 0.1 3.2e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 AAS50633.2 - 6.3e-12 44.8 0.0 1.8e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 KH domain SHR3_chaperone PF08229.6 AAS50634.1 - 3.7e-82 274.0 1.3 4.4e-82 273.7 0.9 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Tetraspannin PF00335.15 AAS50634.1 - 0.03 13.6 3.6 0.46 9.7 2.5 2.1 1 1 0 1 1 1 0 Tetraspanin family DUF2463 PF09591.5 AAS50634.1 - 0.081 12.5 0.5 0.17 11.4 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) Uteroglobin PF01099.12 AAS50634.1 - 0.085 12.6 0.2 0.96 9.2 0.0 2.2 2 0 0 2 2 2 0 Uteroglobin family Permease PF02405.11 AAS50634.1 - 0.62 9.5 4.9 5.1 6.5 0.3 2.6 2 1 1 3 3 3 0 Permease TctB PF07331.6 AAS50634.1 - 0.97 9.0 7.2 5.3 6.6 0.0 3.1 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Cation_efflux PF01545.16 AAS50634.1 - 2 7.4 5.1 11 5.0 3.5 2.2 1 1 0 1 1 1 0 Cation efflux family Ribosomal_L22 PF00237.14 AAS50635.1 - 1.1e-19 70.2 0.0 2.2e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e COX14 PF14880.1 AAS50636.2 - 0.015 14.8 0.3 0.03 13.9 0.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Alpha_GJ PF03229.8 AAS50636.2 - 9.6 6.5 11.5 3.1 8.1 3.4 2.8 1 1 1 2 2 2 0 Alphavirus glycoprotein J RRM_1 PF00076.17 AAS50637.2 - 3.7e-27 93.7 0.2 7.1e-17 60.8 0.0 3.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS50637.2 - 5.6e-22 77.5 0.1 7.7e-13 48.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS50637.2 - 8.3e-11 41.5 0.2 2.2e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AAS50637.2 - 0.0024 17.6 0.0 0.0065 16.2 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif FtsA PF14450.1 AAS50637.2 - 0.062 13.1 0.1 7.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Cell division protein FtsA Peptidase_S49_N PF08496.5 AAS50637.2 - 0.11 12.3 2.3 0.15 11.8 1.3 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal HTH_19 PF12844.2 AAS50637.2 - 0.13 12.3 0.6 0.24 11.4 0.4 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Ubie_methyltran PF01209.13 AAS50639.1 - 1.7e-97 325.0 0.0 2e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 AAS50639.1 - 7e-13 48.4 0.0 1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AAS50639.1 - 3.6e-10 40.1 0.0 6.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AAS50639.1 - 4.3e-09 36.7 0.0 7.5e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AAS50639.1 - 2e-07 31.3 0.0 3.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AAS50639.1 - 3.4e-07 30.1 0.0 5.2e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS50639.1 - 3.8e-06 27.4 0.0 6.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AAS50639.1 - 0.00028 20.9 0.0 0.00099 19.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 AAS50639.1 - 0.035 13.7 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.12 AAS50639.1 - 0.046 13.1 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_5 PF01795.14 AAS50639.1 - 0.086 12.0 0.0 0.2 10.8 0.0 1.5 2 0 0 2 2 2 0 MraW methylase family Methyltransf_8 PF05148.10 AAS50639.1 - 0.091 12.3 0.0 0.36 10.4 0.0 1.9 1 1 1 2 2 2 0 Hypothetical methyltransferase Bul1_N PF04425.7 AAS50640.1 - 5.6e-159 529.3 0.2 5.6e-159 529.3 0.2 1.6 2 0 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.7 AAS50640.1 - 2.5e-111 371.2 6.5 5.1e-111 370.2 4.5 1.6 1 0 0 1 1 1 1 Bul1 C terminus CTK3_C PF12350.3 AAS50641.1 - 2.1e-21 75.6 4.4 4.3e-21 74.7 3.1 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.3 AAS50641.1 - 8.6e-07 28.6 0.0 2.6e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 ubiquitin PF00240.18 AAS50642.1 - 1.5e-19 69.1 0.1 2.1e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AAS50642.1 - 7.8e-12 44.7 0.0 1.1e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 AAS50642.1 - 9.2e-08 31.7 0.1 2.3e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD_2 PF13881.1 AAS50642.1 - 9.9e-05 22.1 0.1 0.00023 21.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AAS50642.1 - 0.00028 21.0 0.0 0.00055 20.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 AAS50642.1 - 0.0065 16.6 0.0 0.0093 16.1 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain L27_2 PF09045.5 AAS50642.1 - 0.12 11.9 0.1 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 L27_2 Ribosomal_60s PF00428.14 AAS50642.1 - 7.9 6.9 16.0 1.6 9.1 1.9 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein TAF8_C PF10406.4 AAS50643.1 - 5.8e-23 80.6 1.9 5.8e-23 80.6 1.3 2.0 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 AAS50643.1 - 0.044 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated NIF PF03031.13 AAS50644.2 - 1.1e-23 83.6 0.2 3.9e-23 81.8 0.0 2.0 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.21 AAS50644.2 - 9.9e-13 48.0 0.2 3.5e-12 46.2 0.0 2.1 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AAS50644.2 - 1.2e-08 34.6 0.0 2.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Biotin_lipoyl_2 PF13533.1 AAS50644.2 - 0.00041 19.9 0.0 0.49 10.1 0.0 2.5 2 0 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.17 AAS50644.2 - 0.018 14.7 0.0 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Biotin-requiring enzyme TMPIT PF07851.8 AAS50644.2 - 7.3 5.5 5.2 11 4.9 3.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein PGM_PMM_I PF02878.11 AAS50645.1 - 1.3e-35 121.8 0.0 3.1e-35 120.6 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 AAS50645.1 - 5.1e-21 74.9 0.0 1.1e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 AAS50645.1 - 1.3e-15 57.3 0.1 4.3e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 AAS50645.1 - 2.3e-05 24.3 0.0 6.1e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF4434 PF14488.1 AAS50645.1 - 0.048 13.3 0.4 9.6 5.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) S-methyl_trans PF02574.11 AAS50646.1 - 3.9e-77 259.5 0.0 4.5e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Kelch_1 PF01344.20 AAS50646.1 - 0.12 11.9 0.5 0.93 9.0 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Anp1 PF03452.9 AAS50647.2 - 2.9e-122 407.0 0.0 3.6e-122 406.7 0.0 1.1 1 0 0 1 1 1 1 Anp1 Asp PF00026.18 AAS50648.1 - 1.1e-38 133.2 0.0 1.8e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AAS50648.1 - 1.2e-05 25.2 0.1 8.4e-05 22.5 0.1 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 AAS50648.1 - 2e-05 24.1 0.0 0.0001 21.8 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 AAS50648.1 - 0.0033 17.8 0.4 1.9 9.0 0.0 3.2 2 1 0 2 2 2 2 Aspartyl protease Nab6_mRNP_bdg PF10567.4 AAS50649.2 - 1.2e-109 366.1 7.9 2.4e-109 365.0 5.5 1.6 1 0 0 1 1 1 1 RNA-recognition motif RRM PF10378.4 AAS50649.2 - 2.7e-23 81.3 10.6 2.7e-23 81.3 7.4 2.9 3 0 0 3 3 3 1 Putative RRM domain RRM_6 PF14259.1 AAS50649.2 - 2e-10 40.4 0.0 0.00035 20.4 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS50649.2 - 5.4e-07 29.3 0.1 0.0092 15.8 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AAS50649.2 - 1.3e-06 27.9 0.0 0.031 13.8 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 AAS50650.2 - 7.6e-39 133.1 0.6 1.6e-38 132.1 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS50650.2 - 1.6e-10 40.7 13.0 2.5e-10 40.0 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.16 AAS50650.2 - 2.9 7.9 6.3 0.19 11.7 0.3 2.0 2 0 0 2 2 2 0 bZIP transcription factor PIG-L PF02585.12 AAS50651.1 - 1.7e-21 77.0 0.1 2.6e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF4507 PF14964.1 AAS50651.1 - 0.12 11.0 0.3 0.18 10.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) ATP13 PF12921.2 AAS50652.2 - 7.7e-07 28.5 0.0 1.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATPase expression Exo_endo_phos PF03372.18 AAS50653.1 - 3.7e-23 82.7 0.0 4.9e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ku PF02735.11 AAS50654.1 - 1.7e-22 79.8 0.0 3e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 AAS50654.1 - 1.2e-05 24.8 0.0 2.7e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 AAS50654.1 - 0.0062 17.0 0.2 0.0062 17.0 0.1 1.8 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm Ribosomal_S27e PF01667.12 AAS50654.1 - 0.088 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 AA_permease_2 PF13520.1 AAS50655.2 - 2.3e-59 201.0 58.8 2.8e-59 200.7 40.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AAS50655.2 - 1.2e-17 63.3 51.3 1.8e-17 62.9 35.6 1.1 1 0 0 1 1 1 1 Amino acid permease Ribosomal_L7Ae PF01248.21 AAS50656.1 - 8.5e-28 95.7 0.3 1.3e-27 95.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 AAS50656.1 - 0.001 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 RVT_connect PF06815.8 AAS50656.1 - 0.11 12.3 0.1 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase connection domain Ino80_Iec3 PF14612.1 AAS50657.1 - 0.099 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Adaptin_N PF01602.15 AAS50659.1 - 5.1e-100 335.2 16.8 1e-99 334.2 11.7 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 AAS50659.1 - 8e-58 193.7 0.0 2e-57 192.4 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 AAS50659.1 - 6.4e-50 168.4 0.0 2.1e-49 166.7 0.0 2.0 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 AAS50659.1 - 1.6e-07 31.5 7.8 0.0016 18.6 0.0 5.0 3 1 2 5 5 5 4 HEAT repeats Vac14_Fab1_bd PF12755.2 AAS50659.1 - 0.046 14.1 1.1 0.24 11.7 0.1 2.7 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Ribosomal_L5_C PF00673.16 AAS50660.2 - 6.7e-21 73.8 0.0 1.5e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AAS50660.2 - 8.9e-08 31.8 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 GLE1 PF07817.8 AAS50661.1 - 4.5e-91 304.3 0.0 8.2e-91 303.4 0.0 1.4 1 0 0 1 1 1 1 GLE1-like protein CAF-1_p150 PF11600.3 AAS50661.1 - 0.045 13.1 39.9 0.072 12.4 27.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.6 AAS50661.1 - 0.36 10.6 25.9 0.54 10.0 17.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Peptidase_S64 PF08192.6 AAS50661.1 - 3.2 5.9 4.7 4.8 5.3 3.3 1.3 1 0 0 1 1 1 0 Peptidase family S64 DUF1501 PF07394.7 AAS50661.1 - 4.6 5.9 11.0 6.6 5.4 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Mgr1 PF08602.5 AAS50661.1 - 5.1 6.0 8.7 7.9 5.3 6.1 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Flavokinase PF01687.12 AAS50662.1 - 3.7e-35 120.5 0.0 4.8e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase TPR_14 PF13428.1 AAS50663.2 - 0.0032 17.9 0.7 27 5.7 0.0 4.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 AAS50663.2 - 0.0071 16.2 0.2 2.5 8.0 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat Sir1 PF11603.3 AAS50663.2 - 0.032 14.3 0.5 0.084 13.0 0.3 1.7 1 0 0 1 1 1 0 Regulatory protein Sir1 TPR_19 PF14559.1 AAS50663.2 - 0.14 12.5 2.7 0.28 11.5 0.1 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Porphobil_deam PF01379.15 AAS50664.1 - 1.3e-84 282.4 0.0 1.7e-84 282.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 AAS50664.1 - 1.2e-21 76.5 0.2 2.2e-21 75.7 0.2 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Aconitase PF00330.15 AAS50665.2 - 3.1e-72 243.5 0.0 5.4e-46 157.0 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AAS50665.2 - 9.9e-27 93.6 0.0 1.7e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Reticulon PF02453.12 AAS50666.1 - 6e-42 143.1 2.9 7.9e-42 142.7 2.0 1.1 1 0 0 1 1 1 1 Reticulon Aminotran_1_2 PF00155.16 AAS50667.1 - 1.9e-70 237.6 0.0 2.4e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 AAS50667.1 - 7.6e-08 31.0 0.0 1.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AAS50667.1 - 5e-06 25.4 0.0 7.7e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AAS50667.1 - 2.6e-05 23.5 0.1 5.7e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 AAS50667.1 - 0.015 14.3 0.3 0.28 10.1 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family WD40_alt PF14077.1 AAS50668.2 - 0.14 11.7 1.0 1.8 8.2 0.1 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF342 PF03961.8 AAS50668.2 - 6.7 4.9 14.1 4.2 5.6 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DAHP_synth_1 PF00793.15 AAS50669.1 - 7.7e-99 329.7 0.0 9.4e-99 329.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Cellulase PF00150.13 AAS50670.1 - 5.2e-10 38.9 3.2 5.2e-10 38.9 2.3 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) PRP1_N PF06424.7 AAS50671.1 - 6.3e-31 107.4 0.7 1.3e-30 106.4 0.5 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 AAS50671.1 - 2.9e-25 86.4 1.5 0.00089 19.6 0.0 9.9 8 2 2 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 AAS50671.1 - 2.6e-16 59.7 0.1 3.4e-07 30.5 0.0 6.6 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 AAS50671.1 - 2.3e-14 52.7 0.1 0.00032 20.2 0.0 6.5 5 2 1 6 6 6 4 TPR repeat TPR_16 PF13432.1 AAS50671.1 - 5.3e-11 42.8 0.0 9.5e-05 22.9 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 AAS50671.1 - 2.7e-06 26.8 0.0 0.071 13.0 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 AAS50671.1 - 3.4e-05 23.6 0.1 0.022 14.6 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 AAS50671.1 - 0.00012 22.0 0.2 13 6.2 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 AAS50671.1 - 0.00032 20.7 0.4 0.5 10.5 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AAS50671.1 - 0.00089 19.0 0.2 12 5.8 0.1 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat Suf PF05843.9 AAS50671.1 - 0.0018 18.0 2.4 1.8 8.2 0.0 4.3 2 2 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_1 PF00515.23 AAS50671.1 - 0.011 15.2 0.0 0.067 12.8 0.0 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 AAS50671.1 - 0.023 15.1 0.2 26 5.5 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 AAS50671.1 - 0.03 14.1 0.4 5.9 6.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.3 AAS50672.1 - 7.1e-22 77.5 0.3 2.9e-21 75.5 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS50672.1 - 3e-06 27.0 13.0 5.3e-06 26.2 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SGL PF08450.7 AAS50673.1 - 8.9e-69 231.5 0.0 1.1e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 AAS50673.1 - 0.0006 19.7 0.0 0.84 9.6 0.0 3.1 3 0 0 3 3 3 2 Arylesterase CHCH PF06747.8 AAS50674.1 - 3.9e-05 23.4 13.9 0.021 14.7 2.4 2.5 2 0 0 2 2 2 2 CHCH domain UPF0203 PF05254.7 AAS50674.1 - 9.9e-05 22.1 6.5 0.021 14.6 0.6 2.5 2 2 0 2 2 2 2 Uncharacterised protein family (UPF0203) COX6B PF02297.12 AAS50674.1 - 0.00063 19.7 8.8 0.005 16.8 0.8 2.1 1 1 1 2 2 2 2 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 AAS50674.1 - 0.03 14.1 14.0 0.041 13.6 2.8 2.3 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 AAS50674.1 - 0.055 13.5 11.7 0.096 12.7 1.8 2.7 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.11 AAS50674.1 - 0.13 12.2 9.6 0.36 10.8 1.4 2.4 1 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.8 AAS50674.1 - 1.9 8.5 8.5 3.6 7.6 0.4 2.8 3 0 0 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) WD40 PF00400.27 AAS50675.2 - 9.7e-13 47.4 8.7 0.0015 18.3 0.0 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF1752 PF08550.5 AAS50676.1 - 1.2e-10 40.7 1.4 3.3e-10 39.3 1.0 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Pex2_Pex12 PF04757.9 AAS50677.1 - 9.6e-21 74.2 12.4 1.9e-20 73.3 8.6 1.4 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 AAS50677.1 - 0.019 14.9 8.8 0.06 13.3 6.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Myb_DNA-bind_6 PF13921.1 AAS50679.1 - 9.3e-19 67.2 20.3 1.5e-15 57.0 1.6 4.4 3 2 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AAS50679.1 - 1.6e-18 66.4 15.7 1.9e-09 37.4 0.5 5.7 5 1 0 5 5 5 3 Myb-like DNA-binding domain DUF1436 PF07262.6 AAS50679.1 - 0.0041 16.6 1.7 0.1 12.0 0.1 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF1436) MADF_DNA_bdg PF10545.4 AAS50679.1 - 0.078 13.1 11.8 0.52 10.5 0.6 4.1 2 2 2 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MRP-S31 PF15433.1 AAS50679.1 - 4 6.7 14.4 7.1 5.9 5.7 2.3 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Ribosomal_S17 PF00366.15 AAS50680.1 - 1.5e-30 104.9 3.4 2.5e-30 104.3 2.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 ADH_zinc_N PF00107.21 AAS50681.1 - 3.9e-30 104.0 0.0 1e-29 102.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AAS50681.1 - 3.5e-11 42.8 0.0 1.9e-10 40.4 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AAS50681.1 - 3.6e-06 27.8 0.0 8.6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 AAS50681.1 - 0.043 13.8 0.2 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Trypan_glycop PF00913.14 AAS50682.2 - 0.016 14.1 0.4 0.036 12.9 0.3 1.6 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) tRNA-synt_2b PF00587.20 AAS50683.1 - 1.2e-36 125.9 0.0 2.3e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 AAS50683.1 - 1.8e-24 85.8 10.1 1.8e-24 85.8 7.0 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF4164 PF13747.1 AAS50683.1 - 0.017 15.2 3.8 0.039 14.0 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.7 AAS50683.1 - 0.038 13.7 9.1 0.025 14.3 4.9 1.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Occludin_ELL PF07303.8 AAS50683.1 - 5.4 7.8 10.8 1.2 9.8 3.5 2.5 3 0 0 3 3 3 0 Occludin homology domain Mgm101p PF06420.7 AAS50685.1 - 1.5e-90 301.0 0.0 2.1e-90 300.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 PMT PF02366.13 AAS50686.2 - 5.2e-78 261.7 22.9 1.2e-77 260.6 15.9 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 AAS50686.2 - 7.3e-24 84.3 0.4 1.2e-23 83.6 0.2 1.3 1 0 0 1 1 1 1 MIR domain NUDIX PF00293.23 AAS50687.2 - 0.0005 19.7 0.0 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain 5_3_exonuc_N PF02739.11 AAS50687.2 - 0.07 12.4 0.1 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain DHHA2 PF02833.9 AAS50688.1 - 2.3e-23 82.7 0.1 4.6e-23 81.8 0.1 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 AAS50688.1 - 3.7e-11 42.8 0.1 7.4e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 DHH family Ste50p-SAM PF09235.5 AAS50688.1 - 0.026 14.5 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 Ste50p, sterile alpha motif Phospholip_B PF04916.8 AAS50688.1 - 0.075 11.1 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Phospholipase B HECT_2 PF09814.4 AAS50689.1 - 3.7e-78 262.7 0.0 4.1e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding BBIP10 PF14777.1 AAS50689.1 - 0.033 13.5 0.1 0.18 11.1 0.0 2.1 1 1 1 2 2 2 0 Cilia BBSome complex subunit 10 DRIM PF07539.7 AAS50690.2 - 0.0012 18.2 1.0 0.36 10.2 0.1 3.6 3 0 0 3 3 3 2 Down-regulated in metastasis Homoserine_dh PF00742.14 AAS50691.1 - 4.6e-53 179.5 0.0 6e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 AAS50691.1 - 1.8e-17 63.8 0.0 2.9e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF3608 PF12257.3 AAS50692.2 - 5.3e-143 475.0 1.5 1.1e-142 474.0 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 AAS50692.2 - 6e-26 89.9 0.1 1.7e-25 88.5 0.1 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) VWA_2 PF13519.1 AAS50693.1 - 1.3e-10 41.6 0.1 2.4e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 AAS50693.1 - 5.6e-07 29.3 0.2 8.2e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like DUF1887 PF09002.6 AAS50693.1 - 0.017 13.5 0.1 0.025 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) UIM PF02809.15 AAS50693.1 - 0.027 14.0 1.5 0.079 12.5 1.1 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif PDH PF02153.12 AAS50693.1 - 0.064 12.1 0.4 0.32 9.8 0.3 1.9 1 1 1 2 2 2 0 Prephenate dehydrogenase NIR_SIR PF01077.17 AAS50694.2 - 6.1e-50 168.6 0.0 2e-45 153.9 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 AAS50694.2 - 1.8e-27 94.7 0.0 1.3e-12 47.1 0.0 2.8 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 AAS50694.2 - 8.1e-25 87.4 0.0 1.6e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin TraF PF13728.1 AAS50694.2 - 0.026 14.0 0.1 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein Chalcone PF02431.10 AAS50695.1 - 4.7e-56 189.3 0.0 5.8e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase DUF2454 PF10521.4 AAS50696.1 - 1.8e-74 250.3 1.2 2.2e-74 250.0 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Proteasom_PSMB PF10508.4 AAS50696.1 - 0.013 13.8 0.1 0.022 13.0 0.1 1.3 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit zf-Tim10_DDP PF02953.10 AAS50697.1 - 1.4e-20 72.2 3.0 1.7e-20 72.0 2.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF1767 PF08585.7 AAS50697.1 - 0.12 12.6 0.4 0.21 11.8 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1767) Myosin_tail_1 PF01576.14 AAS50698.2 - 0.021 12.5 4.1 0.63 7.6 0.4 2.0 2 0 0 2 2 2 0 Myosin tail SlyX PF04102.7 AAS50698.2 - 0.092 13.1 0.5 0.092 13.1 0.4 2.1 2 0 0 2 2 2 0 SlyX HAUS-augmin3 PF14932.1 AAS50698.2 - 0.57 9.3 5.6 0.075 12.2 0.3 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 RIX1 PF08167.7 AAS50699.2 - 2.3e-46 157.4 0.6 6.1e-46 156.1 0.1 2.1 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis ParcG PF10274.4 AAS50699.2 - 0.00072 19.5 0.5 0.22 11.4 0.1 2.6 2 0 0 2 2 2 2 Parkin co-regulated protein TMF_TATA_bd PF12325.3 AAS50700.1 - 5.9e-34 116.3 11.8 5.9e-34 116.3 8.2 5.7 2 1 4 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 AAS50700.1 - 6e-07 29.1 22.6 6e-07 29.1 15.7 7.9 5 3 3 8 8 8 5 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 AAS50700.1 - 0.0061 16.5 4.1 0.0061 16.5 2.9 6.3 3 2 2 6 6 6 1 Domain of unknown function (DUF4200) MAD PF05557.8 AAS50700.1 - 0.018 13.1 63.2 0.0073 14.4 32.0 2.3 2 0 0 2 2 2 0 Mitotic checkpoint protein CENP-Q PF13094.1 AAS50700.1 - 0.16 12.0 71.2 0.14 12.2 15.8 5.3 2 1 4 6 6 6 0 CENP-Q, a CENPA-CAD centromere complex subunit FlaC_arch PF05377.6 AAS50700.1 - 0.28 11.1 12.1 0.84 9.5 0.6 4.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) MtrB PF05440.7 AAS50700.1 - 0.43 10.6 1.9 3.9 7.5 0.1 2.8 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B NPV_P10 PF05531.7 AAS50700.1 - 2.7 8.2 14.3 2.5 8.3 1.7 4.3 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 AAS50700.1 - 3.4 6.7 17.0 1.1 8.3 1.3 3.9 2 2 1 4 4 4 0 Reovirus sigma C capsid protein DUF948 PF06103.6 AAS50700.1 - 6.1 6.7 12.4 0.81 9.5 2.1 3.7 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Pribosyltran PF00156.22 AAS50701.2 - 3.6e-13 49.3 0.4 4.8e-12 45.6 0.3 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain IBN_N PF03810.14 AAS50703.2 - 4.7e-13 48.8 0.0 3.6e-11 42.8 0.0 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.5 AAS50703.2 - 5.4e-05 21.9 1.0 0.00018 20.2 0.0 2.4 3 0 0 3 3 3 1 Cse1 MDM31_MDM32 PF08118.6 AAS50705.1 - 6.3e-294 974.9 0.6 7.2e-294 974.8 0.4 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins PCI PF01399.22 AAS50706.1 - 8.6e-07 29.2 0.6 8.1e-06 26.0 0.0 2.7 2 0 0 2 2 2 1 PCI domain DUF2064 PF09837.4 AAS50706.1 - 0.013 15.0 0.0 0.042 13.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) GLTP PF08718.6 AAS50707.1 - 2.7e-45 154.0 0.1 5.4e-45 153.0 0.0 1.5 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) Recep_L_domain PF01030.19 AAS50708.2 - 5.7e-09 35.9 10.7 0.036 14.0 0.0 5.0 1 1 2 3 3 3 3 Receptor L domain LRR_5 PF13306.1 AAS50708.2 - 0.001 18.7 5.1 0.0059 16.3 0.4 2.7 1 1 1 2 2 2 1 Leucine rich repeats (6 copies) LRR_8 PF13855.1 AAS50708.2 - 0.0043 16.7 5.6 0.63 9.8 0.0 3.8 4 0 0 4 4 4 2 Leucine rich repeat Ecm33 PF12454.3 AAS50708.2 - 0.0067 16.2 3.0 0.024 14.4 2.1 2.0 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein RL11D PF11088.3 AAS50708.2 - 0.041 13.6 0.4 0.14 11.9 0.3 1.9 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 LRR_9 PF14580.1 AAS50708.2 - 0.053 13.0 0.6 0.16 11.4 0.4 1.8 1 0 0 1 1 1 0 Leucine-rich repeat SAM_decarbox PF01536.11 AAS50710.1 - 3.5e-107 357.9 0.0 4e-107 357.7 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase RRM_1 PF00076.17 AAS50712.1 - 7.9e-26 89.4 0.3 1.4e-14 53.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS50712.1 - 1.8e-19 69.4 0.0 1.2e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS50712.1 - 1.4e-11 44.0 0.1 7.3e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 AAS50713.2 - 7.5e-08 32.0 6.9 1.6e-07 31.0 4.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AAS50713.2 - 2.4e-07 30.7 1.7 6e-07 29.4 1.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 AAS50713.2 - 1.2e-05 25.2 3.3 2.9e-05 23.9 2.3 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 AAS50713.2 - 0.00071 19.3 1.3 0.0018 18.0 0.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 AAS50713.2 - 0.05 13.6 8.3 0.06 13.3 3.8 2.4 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4 PF00097.20 AAS50713.2 - 0.053 13.1 7.1 0.13 11.9 4.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS50713.2 - 0.11 12.5 8.3 0.32 11.0 5.8 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AAS50713.2 - 0.52 10.0 4.8 1.6 8.4 3.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 AAS50713.2 - 0.7 9.9 6.2 1.8 8.6 4.3 1.7 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 AAS50713.2 - 3.6 7.2 9.1 1.1e+02 2.4 4.0 3.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain CS PF04969.11 AAS50714.1 - 0.0014 19.0 0.0 0.0027 18.1 0.0 1.5 1 0 0 1 1 1 1 CS domain Fork_head_N PF08430.7 AAS50714.1 - 0.13 12.6 11.3 0.19 12.1 7.8 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region Aldose_epim PF01263.15 AAS50715.1 - 3.6e-52 177.3 0.4 4.4e-52 177.0 0.3 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase PF00069.20 AAS50716.1 - 6.2e-49 166.4 0.0 8.6e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS50716.1 - 1.3e-19 70.2 0.0 1e-18 67.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase AP_endonuc_2 PF01261.19 AAS50717.1 - 2.3e-28 98.9 0.1 3.3e-28 98.4 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel XPG_N PF00752.12 AAS50719.2 - 3.4e-35 120.3 0.0 6.7e-35 119.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 AAS50719.2 - 5.3e-28 96.9 0.0 1.2e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 AAS50719.2 - 3.7e-06 27.0 0.7 2.3e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 AAS50719.2 - 0.081 13.1 1.1 0.36 11.0 0.1 2.6 2 1 0 2 2 2 0 Helix-hairpin-helix domain BAF1_ABF1 PF04684.8 AAS50720.2 - 1.1e-140 469.8 25.4 9.4e-80 268.8 1.6 3.2 1 1 2 3 3 3 3 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.10 AAS50720.2 - 0.00054 19.4 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 MuDR family transposase OAD_gamma PF04277.8 AAS50720.2 - 1.6 9.1 8.2 1 9.7 1.9 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain mRNA_stabil PF13929.1 AAS50721.2 - 5.7e-96 320.8 0.9 1.3e-95 319.6 1.0 1.4 2 0 0 2 2 2 1 mRNA stabilisation Oligomerisation PF02410.10 AAS50721.2 - 2.1e-10 40.5 0.0 7.7e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 Oligomerisation domain KTI12 PF08433.5 AAS50722.2 - 1.6e-102 342.3 0.4 1.8e-102 342.1 0.3 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 AAS50722.2 - 8.9e-07 28.8 0.0 2.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AAS50722.2 - 0.00012 22.8 0.0 0.00021 22.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AAS50722.2 - 0.00015 22.0 0.0 0.0007 19.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AAS50722.2 - 0.00024 21.1 0.3 0.44 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain APS_kinase PF01583.15 AAS50722.2 - 0.00097 18.8 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_28 PF13521.1 AAS50722.2 - 0.0025 17.7 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AAS50722.2 - 0.014 15.2 0.0 0.048 13.5 0.0 1.9 2 1 1 3 3 3 0 AAA domain UPF0079 PF02367.12 AAS50722.2 - 0.046 13.3 0.1 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 6PF2K PF01591.13 AAS50722.2 - 0.067 12.2 0.5 5.5 6.0 0.0 2.4 2 1 0 2 2 2 0 6-phosphofructo-2-kinase AAA_22 PF13401.1 AAS50722.2 - 0.078 13.1 0.1 0.26 11.4 0.1 2.4 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 AAS50723.1 - 2.3e-12 46.9 0.0 4.4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 AAS50723.1 - 1.9e-05 23.9 0.0 2.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 AAS50723.1 - 0.00024 20.3 0.0 0.00038 19.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 AAS50723.1 - 0.014 14.2 0.1 0.024 13.4 0.1 1.3 1 0 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 AAS50723.1 - 0.032 13.6 0.4 0.097 12.0 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 AAS50723.1 - 0.07 13.4 0.1 0.24 11.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 AAS50723.1 - 0.2 11.3 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 NTPase NODP PF07684.7 AAS50723.1 - 1.2 8.7 3.8 36 4.0 0.0 2.6 2 0 0 2 2 2 0 NOTCH protein Hap4_Hap_bind PF10297.4 AAS50724.2 - 6.8e-09 35.2 8.5 1.4e-08 34.2 5.9 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 IFP_35_N PF07334.8 AAS50724.2 - 0.0027 17.6 0.1 0.0073 16.2 0.1 1.8 1 0 0 1 1 1 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus Rootletin PF15035.1 AAS50724.2 - 0.0099 15.8 0.2 0.024 14.6 0.2 1.6 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Herpes_BLRF2 PF05812.7 AAS50724.2 - 0.01 15.6 0.4 0.018 14.8 0.3 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Mto2_bdg PF12808.2 AAS50724.2 - 0.059 13.4 3.0 0.18 11.9 2.1 1.8 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HALZ PF02183.13 AAS50724.2 - 0.13 11.9 3.3 0.26 11.0 2.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.10 AAS50724.2 - 0.26 10.8 2.3 0.55 9.7 1.6 1.5 1 0 0 1 1 1 0 Septum formation initiator Drc1-Sld2 PF11719.3 AAS50726.1 - 3.2e-69 234.0 17.3 3.1e-68 230.8 12.0 2.3 1 1 0 1 1 1 1 DNA replication and checkpoint protein SPT6_acidic PF14632.1 AAS50726.1 - 0.7 10.0 8.4 0.6 10.3 1.0 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 AATF-Che1 PF13339.1 AAS50726.1 - 2.6 8.2 9.0 3.5 7.7 2.0 2.6 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor UTP15_C PF09384.5 AAS50727.1 - 5.1e-54 182.0 0.2 7.3e-54 181.4 0.1 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 AAS50727.1 - 3.1e-20 71.2 6.0 2.3e-05 24.1 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat CPSF_A PF03178.10 AAS50727.1 - 0.087 11.8 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 CPSF A subunit region WD40 PF00400.27 AAS50728.1 - 1.2e-28 97.8 28.0 0.00013 21.7 0.2 11.7 11 1 0 11 11 11 8 WD domain, G-beta repeat Nup160 PF11715.3 AAS50728.1 - 0.011 13.8 0.3 0.97 7.4 0.1 2.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 CRC_subunit PF08624.5 AAS50729.1 - 1.2e-57 193.7 0.0 2e-57 192.9 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit YL1 PF05764.8 AAS50729.1 - 0.1 12.2 9.2 0.15 11.6 6.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 AAS50729.1 - 0.34 8.9 9.9 0.43 8.5 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 AAS50729.1 - 1.8 6.4 17.3 2.1 6.1 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 AAS50729.1 - 8.7 4.6 15.5 12 4.2 10.7 1.1 1 0 0 1 1 1 0 Daxx Family Peptidase_M41 PF01434.13 AAS50730.2 - 1.3e-70 237.2 2.6 1.3e-70 237.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 AAS50730.2 - 4e-42 143.5 0.0 1.5e-41 141.6 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 AAS50730.2 - 1.9e-07 31.1 0.0 4.9e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.1 AAS50730.2 - 5.6e-05 23.2 3.2 0.027 14.4 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 AAS50730.2 - 0.00018 22.3 4.1 0.00022 22.0 0.0 3.1 4 0 0 4 4 3 1 AAA domain AAA_5 PF07728.9 AAS50730.2 - 0.00036 20.2 0.0 0.0013 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AAS50730.2 - 0.00058 20.0 1.3 0.17 12.0 0.1 3.4 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.8 AAS50730.2 - 0.003 16.3 0.0 0.0065 15.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 AAS50730.2 - 0.0032 17.4 0.2 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 AAS50730.2 - 0.0032 16.5 0.0 0.0087 15.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AAS50730.2 - 0.0071 16.0 1.4 0.018 14.7 0.6 2.0 2 0 0 2 2 1 1 Part of AAA domain IstB_IS21 PF01695.12 AAS50730.2 - 0.012 15.0 0.0 0.036 13.4 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.1 AAS50730.2 - 0.025 14.4 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 AAS50730.2 - 0.035 13.5 0.7 0.14 11.4 0.2 2.1 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 AAS50730.2 - 0.086 12.7 0.6 0.41 10.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 AAS50730.2 - 0.094 13.0 3.0 0.28 11.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 AAS50730.2 - 0.3 11.0 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain U79_P34 PF03064.11 AAS50730.2 - 3.9 6.9 23.7 1.8 8.0 8.8 2.4 2 0 0 2 2 2 0 HSV U79 / HCMV P34 MFS_1 PF07690.11 AAS50731.1 - 3.9e-39 134.3 37.2 3e-38 131.4 25.7 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AAS50731.1 - 2.4e-15 56.0 9.6 2.4e-15 56.0 6.7 3.1 3 1 1 4 4 4 1 Sugar (and other) transporter Macro_2 PF14519.1 AAS50732.2 - 3.3e-65 219.9 0.0 1.1e-64 218.3 0.0 1.6 1 1 0 1 1 1 1 Macro-like domain Aminotran_1_2 PF00155.16 AAS50733.2 - 1.5e-76 257.7 0.0 1.7e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SIS PF01380.17 AAS50735.2 - 2.1e-58 195.5 0.0 2.7e-30 104.6 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 AAS50735.2 - 3.8e-31 108.0 0.1 1.5e-22 79.8 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 AAS50735.2 - 3.1e-20 72.4 0.0 6.6e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 AAS50735.2 - 5.3e-13 48.8 0.0 1.2e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 AAS50735.2 - 8.2e-10 37.8 0.1 1.5e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Peptidase_M18 PF02127.10 AAS50736.2 - 2.8e-119 398.4 0.0 3.3e-119 398.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 AAS50736.2 - 0.00056 18.7 0.0 0.32 9.6 0.0 2.4 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Pkinase PF00069.20 AAS50737.1 - 1.9e-77 259.9 0.0 2.9e-77 259.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS50737.1 - 9.5e-41 139.5 0.0 1.6e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 AAS50737.1 - 0.0027 17.2 0.1 0.0062 16.1 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 AAS50737.1 - 0.0057 15.7 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AAS50737.1 - 0.0083 15.8 0.0 0.024 14.4 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family ADH_N PF08240.7 AAS50738.1 - 1.9e-29 101.5 0.5 3.6e-29 100.6 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AAS50738.1 - 3.7e-28 97.6 0.3 5.7e-28 97.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AAS50738.1 - 4.2e-06 27.6 0.1 1.1e-05 26.2 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Utp11 PF03998.8 AAS50739.1 - 1.8e-75 253.8 30.8 2.1e-75 253.7 21.4 1.0 1 0 0 1 1 1 1 Utp11 protein Sigma54_activ_2 PF14532.1 AAS50740.2 - 0.027 14.5 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Ku PF02735.11 AAS50741.3 - 2.8e-31 108.4 0.1 4.6e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 AAS50741.3 - 5.2e-09 35.8 0.4 7.7e-09 35.3 0.3 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain PGM_PMM_I PF02878.11 AAS50742.1 - 2.1e-33 114.6 0.2 3.3e-33 114.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 AAS50742.1 - 5.4e-24 84.4 0.0 1e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 AAS50742.1 - 2.2e-12 47.2 0.0 5.7e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 AAS50742.1 - 2.2e-08 33.9 0.0 7.1e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Fer4_12 PF13353.1 AAS50742.1 - 0.0083 16.2 0.1 0.051 13.6 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain CBM_4_9 PF02018.12 AAS50742.1 - 0.046 13.7 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain Pkinase PF00069.20 AAS50743.2 - 4.5e-70 235.7 0.0 7.2e-70 235.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS50743.2 - 1.2e-31 109.7 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 AAS50743.2 - 4.1e-10 40.0 0.4 1.1e-09 38.6 0.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 AAS50743.2 - 0.0017 17.3 0.0 0.0076 15.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AAS50743.2 - 0.026 13.5 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AAS50743.2 - 0.056 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4169 PF13770.1 AAS50743.2 - 0.061 13.2 1.3 0.11 12.3 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4169) RRN3 PF05327.6 AAS50744.1 - 7.6e-189 628.4 5.4 8.8e-189 628.2 3.7 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 zf-SAP30 PF13866.1 AAS50744.1 - 0.086 12.5 0.1 4.4 7.0 0.0 2.5 2 0 0 2 2 2 0 SAP30 zinc-finger DUF2457 PF10446.4 AAS50744.1 - 2.6 6.6 11.0 4.1 6.0 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SPRY PF00622.23 AAS50745.2 - 2.5e-10 40.5 0.0 5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 SPRY domain SRP9-21 PF05486.7 AAS50746.2 - 8.1e-23 79.9 0.0 1.1e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribosomal_60s PF00428.14 AAS50746.2 - 0.25 11.7 7.5 0.28 11.5 4.4 1.9 1 1 0 2 2 2 0 60s Acidic ribosomal protein WD40 PF00400.27 AAS50747.1 - 1.8e-24 84.6 14.0 2.2e-07 30.5 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 AAS50747.1 - 0.11 10.8 0.0 0.73 8.0 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.3 AAS50747.1 - 0.22 9.5 3.7 1.5 6.9 0.4 3.1 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Mito_carr PF00153.22 AAS50748.2 - 1.4e-51 172.1 4.2 4.9e-17 61.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Prenyltransf PF01255.14 AAS50749.2 - 1.7e-72 243.1 0.2 2.4e-72 242.6 0.2 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Vma12 PF11712.3 AAS50750.2 - 3.2e-31 107.9 0.0 4.9e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-MYND PF01753.13 AAS50751.1 - 1.4e-05 24.8 23.4 3.1e-05 23.7 16.2 1.6 1 1 0 1 1 1 1 MYND finger Abhydrolase_6 PF12697.2 AAS50752.2 - 1.4e-24 87.2 0.0 1.9e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AAS50752.2 - 3.5e-15 56.1 0.0 5.6e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AAS50752.2 - 1.9e-09 37.4 0.0 1.2e-08 34.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 AAS50752.2 - 5.3e-05 22.8 0.1 8.6e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Serine hydrolase Esterase PF00756.15 AAS50752.2 - 0.017 14.5 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.2 AAS50752.2 - 0.031 13.1 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 AAS50752.2 - 0.034 13.5 0.3 0.16 11.3 0.2 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF900 PF05990.7 AAS50752.2 - 0.28 10.4 0.7 1.7 7.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) AMP-binding PF00501.23 AAS50753.1 - 7.8e-79 264.9 0.0 1.1e-78 264.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AAS50753.1 - 0.066 14.1 0.0 0.27 12.2 0.0 2.1 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain RNase_H PF00075.19 AAS50754.2 - 2.6e-21 76.3 0.0 3.9e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 AAS50754.2 - 8.7e-21 73.6 0.0 5.8e-13 48.6 0.0 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin CAP_N PF01213.14 AAS50754.2 - 7.2 5.7 5.8 7.3 5.7 1.6 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Membr_traf_MHD PF10540.4 AAS50755.2 - 1.3e-13 50.9 0.1 6.6e-13 48.6 0.0 2.4 3 0 0 3 3 3 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 AAS50755.2 - 5.1e-10 39.0 0.1 1.4e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 AAS50755.2 - 2.7e-05 22.6 0.7 9.1e-05 20.9 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF810) SWIB PF02201.13 AAS50756.2 - 4.3e-27 93.5 0.1 8.5e-27 92.6 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 AAS50756.2 - 1.3e-09 37.7 0.7 2.8e-09 36.5 0.5 1.6 1 0 0 1 1 1 1 DEK C terminal domain RRS1 PF04939.7 AAS50757.2 - 1.8e-65 219.4 3.3 2e-65 219.2 2.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGEF PF00621.15 AAS50758.2 - 2.4e-15 56.9 2.4 2.4e-15 56.9 1.7 2.5 3 0 0 3 3 3 1 RhoGEF domain VPS11_C PF12451.3 AAS50759.2 - 8.7e-12 44.7 0.1 8.7e-12 44.7 0.1 2.3 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3HC4_2 PF13923.1 AAS50759.2 - 0.00018 21.4 6.1 0.00045 20.1 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AAS50759.2 - 0.00047 19.8 4.9 0.0011 18.5 3.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 AAS50759.2 - 0.00091 19.0 5.8 0.0021 17.8 4.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AAS50759.2 - 0.13 11.9 5.2 0.4 10.3 3.6 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AAS50759.2 - 0.14 12.0 7.9 0.12 12.3 4.1 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING TPR_8 PF13181.1 AAS50759.2 - 0.25 11.1 2.7 1.3 8.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PHD PF00628.24 AAS50759.2 - 9.9 5.9 12.9 0.033 13.8 2.1 2.1 2 0 0 2 2 2 0 PHD-finger Pkinase PF00069.20 AAS50760.2 - 4.9e-66 222.5 0.0 9.7e-66 221.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS50760.2 - 3e-47 160.8 0.0 1.5e-46 158.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 AAS50760.2 - 4.2e-35 119.8 0.1 9.1e-35 118.7 0.1 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 AAS50760.2 - 3.3e-10 39.6 0.1 1.4e-09 37.6 0.1 2.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 AAS50760.2 - 8.8e-09 35.4 0.1 3.5e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 AAS50760.2 - 3.4e-05 22.9 0.0 0.00017 20.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Metallophos PF00149.23 AAS50762.2 - 5.3e-10 39.0 0.4 2.4e-09 36.8 0.4 2.0 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AAS50762.2 - 3.9e-05 23.5 0.0 7.8e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Atg14 PF10186.4 AAS50763.2 - 6.4e-06 25.3 0.9 1e-05 24.6 0.6 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 AAS50763.2 - 0.0018 17.3 1.4 0.0057 15.7 1.0 1.7 1 1 0 1 1 1 1 Autophagy protein Apg6 Folliculin PF11704.3 AAS50764.1 - 5.6e-53 178.9 0.0 7e-53 178.6 0.0 1.1 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Lyase_1 PF00206.15 AAS50765.2 - 1.6e-22 80.0 0.0 3.6e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 AAS50765.2 - 2.2e-18 66.0 0.2 1e-17 63.9 0.0 2.3 3 0 0 3 3 3 1 Adenylosuccinate lyase C-terminus AsiA PF09010.5 AAS50765.2 - 0.045 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Anti-Sigma Factor A DUF1331 PF07048.6 AAS50765.2 - 0.15 11.5 0.1 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Bromodomain PF00439.20 AAS50766.2 - 1.9e-31 107.7 2.4 1.2e-15 57.1 0.4 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 AAS50766.2 - 1.5e-22 79.5 0.2 4.3e-22 78.1 0.1 1.8 1 0 0 1 1 1 1 BAH domain SIR2 PF02146.12 AAS50767.1 - 3.3e-31 108.3 0.0 1.1e-30 106.7 0.0 1.7 1 1 0 1 1 1 1 Sir2 family AA_permease_2 PF13520.1 AAS50768.1 - 5.3e-87 292.0 36.8 6.4e-87 291.8 25.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AAS50768.1 - 3.3e-16 58.6 32.2 5.3e-16 58.0 22.3 1.2 1 0 0 1 1 1 1 Amino acid permease PAP_central PF04928.12 AAS50769.1 - 3.3e-109 363.5 0.0 5.7e-109 362.8 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 AAS50769.1 - 2.7e-48 163.4 2.8 4.4e-48 162.7 1.9 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 AAS50769.1 - 7.1e-11 42.2 0.3 2.1e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain Peptidase_S49 PF01343.13 AAS50769.1 - 0.056 13.2 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 MACPF PF01823.14 AAS50769.1 - 0.99 9.0 7.4 0.15 11.7 2.0 2.0 2 1 0 2 2 2 0 MAC/Perforin domain Dynamin_M PF01031.15 AAS50770.1 - 7.9e-103 343.2 0.0 1.7e-102 342.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 AAS50770.1 - 6.5e-58 195.2 0.0 1.4e-57 194.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 AAS50770.1 - 6.9e-26 89.9 4.5 6.9e-26 89.9 3.1 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 AAS50770.1 - 0.0038 17.1 0.3 0.042 13.7 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AAS50770.1 - 0.04 14.4 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein HTH_9 PF08221.6 AAS50770.1 - 0.1 12.4 0.8 0.31 10.9 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain APS_kinase PF01583.15 AAS50771.1 - 1e-72 242.8 0.0 1.2e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 AAS50771.1 - 9e-08 32.1 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AAS50771.1 - 2.9e-05 24.8 0.4 4.5e-05 24.2 0.3 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AAS50771.1 - 6.5e-05 23.2 0.7 0.00034 20.9 0.5 2.1 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 AAS50771.1 - 0.00064 19.0 0.0 0.00075 18.7 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 AAS50771.1 - 0.0063 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 AAS50771.1 - 0.012 15.8 0.0 0.016 15.4 0.0 1.4 1 1 0 1 1 1 0 ABC transporter CPT PF07931.7 AAS50771.1 - 0.012 15.1 0.3 0.46 10.0 0.2 2.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Snf7 PF03357.16 AAS50772.1 - 7.6e-30 103.5 22.1 7.6e-30 103.5 15.3 1.6 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.9 AAS50772.1 - 9.9e-07 28.3 7.2 1.4e-06 27.7 5.0 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Uds1 PF15456.1 AAS50772.1 - 0.16 11.9 12.1 0.12 12.3 1.0 2.7 2 1 1 3 3 3 0 Up-regulated During Septation DUF87 PF01935.12 AAS50772.1 - 0.42 10.4 7.9 0.32 10.7 0.1 2.1 1 1 0 2 2 2 0 Domain of unknown function DUF87 Lge1 PF11488.3 AAS50772.1 - 1.7 8.9 6.6 8.8 6.6 1.7 2.9 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 Ribosomal_S6 PF01250.12 AAS50773.1 - 3.2e-06 26.8 0.0 4.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 K167R PF08065.7 AAS50773.1 - 0.051 13.6 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 K167R (NUC007) repeat PAP2 PF01569.16 AAS50774.2 - 7.4e-13 48.2 8.6 7.4e-13 48.2 6.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 AAS50774.2 - 1.7e-06 27.7 7.6 1.7e-06 27.7 5.2 2.4 1 1 1 2 2 2 1 PAP2 superfamily Ribosomal_L14e PF01929.12 AAS50775.1 - 1.3e-30 105.5 0.2 2e-30 104.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 AAS50775.1 - 2.6e-05 23.7 0.4 6e-05 22.6 0.3 1.6 1 0 0 1 1 1 1 KOW motif SNARE PF05739.14 AAS50776.1 - 0.012 15.2 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 SNARE domain Baculo_PEP_C PF04513.7 AAS50776.1 - 0.04 13.7 0.1 0.049 13.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus F-actin_cap_A PF01267.12 AAS50777.1 - 9.6e-73 244.5 0.0 1.1e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit VHS PF00790.14 AAS50778.1 - 8.7e-32 109.6 0.1 1.8e-31 108.6 0.1 1.6 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 AAS50778.1 - 2e-16 59.0 0.1 3.3e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AAS50778.1 - 1.4e-15 56.5 0.2 2.3e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 AAS50778.1 - 2e-15 56.0 0.1 3.6e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain TRAM_LAG1_CLN8 PF03798.11 AAS50779.1 - 8.9e-36 123.3 22.5 8.9e-36 123.3 15.6 2.3 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 AAS50779.1 - 2.2e-25 87.9 1.1 5.4e-25 86.6 0.7 1.7 1 0 0 1 1 1 1 TRAM1-like protein Herpes_LMP1 PF05297.6 AAS50779.1 - 0.021 13.7 4.9 0.032 13.1 3.4 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) MOSP_C PF02722.10 AAS50779.1 - 0.029 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Major Outer Sheath Protein C-terminal region Ribosomal_S2 PF00318.15 AAS50780.2 - 5.8e-57 192.3 0.0 1.1e-56 191.4 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S2 Ribosomal_L10 PF00466.15 AAS50782.1 - 1.5e-17 63.3 0.0 2.4e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 HECT PF00632.20 AAS50783.2 - 5.7e-73 245.8 0.0 1.2e-72 244.7 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.20 AAS50784.2 - 1.1e-71 240.9 0.0 1.7e-71 240.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS50784.2 - 2.7e-46 157.7 0.0 4.5e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 AAS50784.2 - 1.1e-21 77.0 0.0 3.3e-21 75.4 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 AAS50784.2 - 1.7e-05 23.9 0.0 2.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AAS50784.2 - 0.029 14.1 0.0 0.13 11.9 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family CENP-C_C PF11699.3 AAS50785.1 - 6.7e-30 102.9 2.2 1.2e-29 102.1 1.5 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 AAS50785.1 - 3.8e-23 82.5 0.3 3.8e-23 82.5 0.2 3.1 3 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 AAS50785.1 - 4.2e-06 26.1 0.0 9.7e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.13 AAS50785.1 - 0.041 13.4 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase CUE PF02845.11 AAS50786.2 - 1.6e-17 62.6 0.9 8.4e-10 37.9 0.1 3.2 3 0 0 3 3 3 2 CUE domain Smr PF01713.16 AAS50786.2 - 1.7e-13 50.5 0.0 3.7e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Smr domain DMA PF03474.9 AAS50786.2 - 4.4e-06 26.4 0.0 0.068 13.0 0.0 3.3 3 0 0 3 3 3 2 DMRTA motif 2OG-FeII_Oxy_3 PF13640.1 AAS50787.2 - 5.9e-12 45.9 0.5 1.1e-11 45.1 0.3 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 AAS50787.2 - 1.1e-05 25.0 0.3 2e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 AAS50787.2 - 0.0022 18.2 0.1 0.0038 17.5 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily bZIP_1 PF00170.16 AAS50788.1 - 3.6e-08 33.2 16.2 6.2e-08 32.4 11.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor V_ATPase_I PF01496.14 AAS50788.1 - 0.00025 19.0 0.7 0.0003 18.8 0.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CASP_C PF08172.7 AAS50788.1 - 0.0019 17.2 0.9 0.0023 16.9 0.6 1.2 1 0 0 1 1 1 1 CASP C terminal Glutaredoxin2_C PF04399.8 AAS50788.1 - 0.0052 16.3 2.5 0.0097 15.4 1.7 1.4 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain bZIP_2 PF07716.10 AAS50788.1 - 0.0094 15.7 18.3 0.0094 15.7 12.7 1.6 1 1 1 2 2 2 2 Basic region leucine zipper HAP1_N PF04849.8 AAS50788.1 - 0.033 13.1 6.1 0.045 12.6 4.2 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF972 PF06156.8 AAS50788.1 - 0.074 13.3 1.2 0.12 12.7 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) AAA_23 PF13476.1 AAS50788.1 - 0.081 13.2 3.4 0.11 12.7 2.4 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 AAS50788.1 - 0.2 10.6 6.2 0.29 10.1 4.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IpaD PF06511.6 AAS50788.1 - 0.28 10.1 1.2 0.36 9.7 0.8 1.1 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD bZIP_Maf PF03131.12 AAS50788.1 - 0.34 11.2 11.9 0.52 10.6 8.3 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF349 PF03993.7 AAS50788.1 - 0.84 9.8 10.5 1.3 9.1 7.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) AAA PF00004.24 AAS50789.1 - 7.3e-13 48.8 0.0 4.3e-11 43.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 AAS50789.1 - 2.2e-09 36.5 0.1 0.00015 20.6 0.0 2.5 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AAS50789.1 - 2.1e-05 24.6 0.0 0.00033 20.8 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AAS50789.1 - 2.3e-05 25.1 0.1 7.4e-05 23.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 AAS50789.1 - 0.00012 22.0 0.8 0.0012 18.9 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 AAS50789.1 - 0.00044 19.9 0.5 0.0018 18.0 0.0 2.2 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AAS50789.1 - 0.00047 20.0 0.5 0.0014 18.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AAS50789.1 - 0.00052 19.1 0.0 0.0013 17.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AAS50789.1 - 0.0023 17.6 0.0 0.0083 15.8 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 AAS50789.1 - 0.0098 16.0 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase DUF258 PF03193.11 AAS50789.1 - 0.014 14.6 0.0 0.051 12.7 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 AAS50789.1 - 0.016 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AAS50789.1 - 0.031 14.5 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 AAS50789.1 - 0.04 13.3 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Thymidylate_kin PF02223.12 AAS50789.1 - 0.041 13.2 0.1 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.7 AAS50789.1 - 0.066 12.2 0.2 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.1 AAS50789.1 - 0.07 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain IPT PF01745.11 AAS50789.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase Sigma54_activ_2 PF14532.1 AAS50789.1 - 0.13 12.3 0.0 0.61 10.1 0.0 2.2 2 1 0 2 2 1 0 Sigma-54 interaction domain CRAL_TRIO PF00650.15 AAS50790.2 - 2.7e-35 121.2 0.0 3.6e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AAS50790.2 - 1.3e-11 44.4 1.3 3.8e-11 42.9 0.9 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AAS50790.2 - 0.0052 16.6 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain RasGAP PF00616.14 AAS50791.2 - 5.9e-49 166.4 2.3 1.1e-48 165.4 1.6 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 AAS50791.2 - 3.2e-05 23.6 0.2 8e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 C2 domain UPF1_Zn_bind PF09416.5 AAS50792.4 - 3.7e-68 227.9 12.5 3.7e-68 227.9 8.7 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 AAS50792.4 - 8.1e-58 195.0 0.0 1.4e-57 194.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AAS50792.4 - 2.2e-52 178.0 1.5 3.6e-52 177.3 1.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 AAS50792.4 - 1.4e-15 57.3 0.3 3.1e-13 49.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AAS50792.4 - 9.1e-14 50.9 0.0 6.2e-13 48.2 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 AAS50792.4 - 2e-06 27.0 0.1 2.2e-05 23.6 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 AAS50792.4 - 3.3e-05 23.7 0.0 8.5e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 AAS50792.4 - 3.9e-05 23.2 0.0 0.24 10.8 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PIF1 PF05970.9 AAS50792.4 - 0.00061 18.8 0.1 0.5 9.2 0.1 2.2 1 1 0 2 2 2 2 PIF1-like helicase Helicase_RecD PF05127.9 AAS50792.4 - 0.00062 19.4 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 Helicase DEAD PF00270.24 AAS50792.4 - 0.02 14.3 0.1 0.048 13.1 0.1 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.11 AAS50792.4 - 0.023 13.9 0.0 0.063 12.5 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Flavi_DEAD PF07652.9 AAS50792.4 - 0.024 14.4 0.1 0.055 13.2 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_16 PF13191.1 AAS50792.4 - 0.039 13.9 0.1 0.09 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.17 AAS50792.4 - 0.048 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain KaiC PF06745.8 AAS50792.4 - 0.048 12.7 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 KaiC T2SE PF00437.15 AAS50792.4 - 0.053 12.4 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Cytochrome-c551 PF10643.4 AAS50793.1 - 0.014 14.6 0.1 0.022 14.0 0.1 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DUF572 PF04502.8 AAS50794.1 - 2e-48 165.2 4.8 2.7e-48 164.8 3.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) TF_Zn_Ribbon PF08271.7 AAS50794.1 - 0.074 12.3 0.4 0.074 12.3 0.2 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding Mu-like_Com PF10122.4 AAS50794.1 - 0.16 11.0 1.7 0.33 10.0 0.2 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com Zn_Tnp_IS1 PF03811.8 AAS50794.1 - 0.22 11.0 0.1 0.22 11.0 0.1 1.8 2 0 0 2 2 2 0 InsA N-terminal domain RNA_pol_Rpb2_6 PF00562.23 AAS50799.2 - 2e-113 379.0 0.0 2.8e-113 378.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AAS50799.2 - 2.8e-44 150.4 0.0 4.1e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 AAS50799.2 - 3.4e-31 108.1 0.0 7.2e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 AAS50799.2 - 4.9e-25 87.0 0.1 8.7e-24 83.0 0.0 3.0 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 AAS50799.2 - 2.2e-24 85.1 0.0 5.8e-24 83.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 AAS50799.2 - 1.7e-15 56.9 0.0 1.2e-14 54.2 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 AAS50799.2 - 0.00013 21.8 0.1 0.00034 20.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Thg1 PF04446.7 AAS50801.1 - 4.9e-47 158.9 0.3 7.1e-47 158.4 0.2 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 AAS50801.1 - 3.9e-37 126.6 0.5 8.1e-37 125.6 0.4 1.5 1 0 0 1 1 1 1 Thg1 C terminal domain Ribosomal_S25 PF03297.10 AAS50803.1 - 6.3e-44 148.3 5.3 7e-44 148.1 3.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 AAS50803.1 - 0.00085 18.9 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Ftsk gamma domain HTH_CodY PF08222.6 AAS50803.1 - 0.019 14.3 0.1 0.03 13.6 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_DeoR PF08220.7 AAS50803.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Ran_BP1 PF00638.13 AAS50804.2 - 7.6e-31 106.6 0.4 1.8e-30 105.5 0.1 1.8 2 0 0 2 2 2 1 RanBP1 domain NUP50 PF08911.6 AAS50804.2 - 2e-09 37.6 0.6 2e-09 37.6 0.4 3.9 3 1 1 4 4 4 1 NUP50 (Nucleoporin 50 kDa) MA3 PF02847.12 AAS50805.3 - 3e-23 81.6 0.2 7.8e-23 80.3 0.1 1.8 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.14 AAS50805.3 - 2.3e-22 79.4 1.7 4.5e-22 78.4 1.1 1.5 1 0 0 1 1 1 1 MIF4G domain DUF4220 PF13968.1 AAS50805.3 - 1.4 7.9 7.7 1.6 7.7 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) AAA PF00004.24 AAS50806.2 - 8.1e-38 129.6 0.0 1.3e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AAS50806.2 - 2.3e-07 30.7 0.0 5.7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AAS50806.2 - 7.5e-07 29.3 0.2 0.00085 19.4 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AAS50806.2 - 9.1e-07 29.7 0.1 3.3e-06 27.9 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 AAS50806.2 - 2.3e-06 27.7 1.3 4.1e-05 23.6 0.1 3.2 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.7 AAS50806.2 - 5.2e-06 25.6 0.0 9.8e-06 24.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 AAS50806.2 - 1e-05 25.3 0.1 7.4e-05 22.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AAS50806.2 - 1.5e-05 24.9 0.0 2.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 AAS50806.2 - 3.8e-05 23.7 0.0 7.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 AAS50806.2 - 0.00012 21.1 0.0 0.00025 20.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 AAS50806.2 - 0.00026 20.4 0.0 0.00051 19.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 AAS50806.2 - 0.00047 20.4 0.0 0.0013 19.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AAS50806.2 - 0.00072 19.0 0.5 0.07 12.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 AAS50806.2 - 0.00075 19.3 0.0 0.003 17.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 AAS50806.2 - 0.00081 18.6 0.2 0.0023 17.1 0.1 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 AAS50806.2 - 0.00082 19.5 0.0 0.0023 18.1 0.0 2.0 1 1 0 1 1 1 1 RNA helicase DUF815 PF05673.8 AAS50806.2 - 0.00088 18.2 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 AAS50806.2 - 0.0066 16.4 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 AAS50806.2 - 0.011 14.4 0.1 0.029 13.0 0.0 1.6 1 1 1 2 2 2 0 TIP49 C-terminus Sigma54_activat PF00158.21 AAS50806.2 - 0.016 14.6 0.0 0.053 12.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 AAS50806.2 - 0.016 14.7 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AAS50806.2 - 0.018 15.3 0.0 0.045 14.0 0.0 1.9 2 1 0 2 2 1 0 ABC transporter AAA_19 PF13245.1 AAS50806.2 - 0.018 14.7 0.0 0.058 13.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 AAS50806.2 - 0.019 14.6 0.1 0.069 12.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.10 AAS50806.2 - 0.023 13.4 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 AAS50806.2 - 0.036 13.6 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 AAS50806.2 - 0.041 13.7 0.0 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase KAP_NTPase PF07693.9 AAS50806.2 - 0.044 12.7 0.5 6.5 5.6 0.0 3.0 2 1 1 3 3 3 0 KAP family P-loop domain Parvo_NS1 PF01057.12 AAS50806.2 - 0.051 12.4 0.0 0.098 11.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 AAS50806.2 - 0.053 13.2 0.1 0.73 9.4 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase Viral_helicase1 PF01443.13 AAS50806.2 - 0.082 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.1 AAS50806.2 - 0.09 12.7 0.3 15 5.4 0.1 2.5 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 AAS50806.2 - 0.1 11.3 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain FCH PF00611.18 AAS50806.2 - 0.13 12.4 0.1 6.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Evr1_Alr PF04777.8 AAS50807.3 - 3.2e-31 107.0 1.9 3.2e-31 107.0 1.3 1.7 2 0 0 2 2 2 1 Erv1 / Alr family WH2 PF02205.15 AAS50808.2 - 7.2e-16 57.2 0.1 1.5e-10 40.3 0.2 2.8 3 0 0 3 3 3 2 WH2 motif OTU PF02338.14 AAS50809.2 - 9.5e-17 61.7 1.2 9.5e-16 58.4 0.0 2.4 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 AAS50809.2 - 0.00036 19.9 0.1 0.0067 15.8 0.0 2.3 3 0 0 3 3 3 1 Peptidase C65 Otubain DUF603 PF04645.7 AAS50809.2 - 0.0071 16.3 1.6 0.015 15.2 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF603 Mig-14 PF07395.6 AAS50809.2 - 0.03 13.3 0.9 0.052 12.5 0.6 1.3 1 0 0 1 1 1 0 Mig-14 DUF1878 PF08963.5 AAS50809.2 - 0.3 11.3 2.7 1.2 9.3 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1878) DivIC PF04977.10 AAS50809.2 - 7.9 6.0 13.6 0.56 9.7 0.9 3.1 2 1 0 2 2 2 0 Septum formation initiator YchF-GTPase_C PF06071.8 AAS50810.2 - 5.9e-33 112.5 0.0 1.1e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 AAS50810.2 - 1.8e-12 47.2 0.0 2.9e-12 46.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 AAS50810.2 - 2e-05 24.3 0.1 0.00011 21.9 0.0 2.1 1 1 0 1 1 1 1 TGS domain FeoB_N PF02421.13 AAS50810.2 - 0.00088 18.5 0.0 0.0022 17.3 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_23 PF13476.1 AAS50810.2 - 0.014 15.7 0.0 0.03 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 AAS50810.2 - 0.025 14.0 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ribosomal_S10 PF00338.17 AAS50811.1 - 4.4e-27 93.7 0.2 5.6e-27 93.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Retrotrans_gag PF03732.12 AAS50811.1 - 0.071 13.1 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 Retrotransposon gag protein RII_binding_1 PF10522.4 AAS50811.1 - 0.53 10.6 2.6 26 5.4 0.2 2.5 2 0 0 2 2 2 0 RII binding domain Cnl2_NKP2 PF09447.5 AAS50811.1 - 0.59 9.8 4.4 0.19 11.4 0.5 1.8 2 0 0 2 2 2 0 Cnl2/NKP2 family protein DUF1688 PF07958.6 AAS50812.2 - 5.4e-160 532.5 0.0 6.1e-160 532.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) SSF PF00474.12 AAS50813.2 - 1.4e-20 73.3 26.7 2.1e-20 72.7 18.5 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Lung_7-TM_R PF06814.8 AAS50814.2 - 7.8e-66 222.0 24.0 9.3e-66 221.7 16.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Nfu_N PF08712.6 AAS50815.1 - 7e-25 86.4 0.1 2.2e-24 84.8 0.0 1.9 3 0 0 3 3 3 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 AAS50815.1 - 2e-22 78.7 0.1 3.6e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.4 AAS50815.1 - 0.015 15.1 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Pterin_4a PF01329.14 AAS50816.1 - 2.9e-26 91.0 0.0 3.5e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Adap_comp_sub PF00928.16 AAS50817.1 - 1.2e-52 178.6 0.0 1.6e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AAS50817.1 - 0.072 12.8 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Opi1 PF08618.5 AAS50818.1 - 8.8e-41 140.2 8.2 1.6e-27 96.5 0.3 3.1 1 1 2 3 3 3 3 Transcription factor Opi1 ATP-synt_ab PF00006.20 AAS50818.1 - 0.037 13.5 0.4 0.056 12.9 0.3 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma_1_2 PF03084.9 AAS50818.1 - 0.078 11.6 0.4 0.12 10.9 0.3 1.3 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family FliJ PF02050.11 AAS50818.1 - 0.91 9.5 15.5 0.084 12.9 6.6 2.2 2 1 0 2 2 2 0 Flagellar FliJ protein Snf7 PF03357.16 AAS50819.2 - 4.2e-29 101.1 16.6 4.2e-29 101.1 11.5 1.8 2 0 0 2 2 2 1 Snf7 PAS_7 PF12860.2 AAS50819.2 - 0.0025 17.8 1.4 0.15 12.0 0.1 2.6 1 1 1 2 2 2 1 PAS fold SurA_N_3 PF13624.1 AAS50819.2 - 0.024 14.6 7.7 0.076 12.9 5.2 2.0 1 1 0 1 1 1 0 SurA N-terminal domain PBP_dimer PF03717.10 AAS50819.2 - 0.19 11.7 4.4 0.078 13.0 1.3 1.6 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain BNIP2 PF12496.3 AAS50819.2 - 0.24 11.5 5.5 0.057 13.5 1.5 1.6 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 ParD PF09386.5 AAS50819.2 - 0.4 10.8 3.1 2.2 8.4 0.1 3.2 2 1 1 3 3 3 0 Antitoxin ParD SpecificRecomb PF10136.4 AAS50819.2 - 0.56 8.1 4.6 0.75 7.7 3.2 1.1 1 0 0 1 1 1 0 Site-specific recombinase MerR-DNA-bind PF09278.6 AAS50819.2 - 8.9 6.8 9.4 3.3 8.1 0.4 3.7 3 1 1 4 4 4 0 MerR, DNA binding CLU PF13236.1 AAS50820.2 - 5.2e-75 251.6 0.3 8.6e-75 250.9 0.2 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 AAS50820.2 - 7.1e-38 130.1 3.1 6.1e-25 88.1 0.0 4.3 4 1 0 4 4 4 2 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 AAS50820.2 - 5.4e-19 68.1 1.5 2.3e-18 66.0 0.2 2.9 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 AAS50820.2 - 1.8e-12 47.0 3.9 2.6e-07 30.4 0.3 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 AAS50820.2 - 1.9e-06 27.5 5.4 0.0043 16.9 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 AAS50820.2 - 0.0012 18.4 0.1 1.8 8.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AAS50820.2 - 0.0027 17.4 1.4 2 8.5 0.1 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 AAS50820.2 - 0.16 11.6 4.6 4.2 7.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 AAS50820.2 - 0.47 10.3 4.3 26 4.9 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CTP_transf_1 PF01148.15 AAS50821.2 - 3.3e-07 30.2 2.2 3.3e-07 30.2 1.5 3.7 2 2 1 3 3 3 2 Cytidylyltransferase family BUD22 PF09073.5 AAS50822.2 - 4e-105 352.3 32.8 4.6e-105 352.1 22.7 1.0 1 0 0 1 1 1 1 BUD22 p450 PF00067.17 AAS50823.1 - 1.7e-46 158.7 0.0 2.2e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2636 PF11120.3 AAS50823.1 - 0.085 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) Spc42p PF11544.3 AAS50824.1 - 8.5e-33 112.1 4.4 9.3e-32 108.8 0.1 2.6 2 0 0 2 2 2 1 Spindle pole body component Spc42p DivIVA PF05103.8 AAS50824.1 - 0.00057 19.9 3.4 0.0074 16.3 0.4 2.4 2 0 0 2 2 2 1 DivIVA protein DUF3338 PF11819.3 AAS50824.1 - 0.031 13.7 1.8 1 8.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) DUF972 PF06156.8 AAS50824.1 - 0.22 11.8 4.6 1.2 9.5 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DNA_pol3_delta PF06144.8 AAS50824.1 - 0.45 10.0 4.9 1.1 8.7 0.1 2.3 2 1 0 2 2 2 0 DNA polymerase III, delta subunit NPV_P10 PF05531.7 AAS50824.1 - 0.88 9.8 8.4 6.1 7.1 0.2 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PhoU PF01895.14 AAS50824.1 - 2 8.9 6.8 29 5.1 0.6 3.2 2 1 1 3 3 3 0 PhoU domain KilA-N PF04383.8 AAS50825.2 - 5.5e-05 22.7 0.0 0.00035 20.1 0.0 2.0 1 1 0 1 1 1 1 KilA-N domain DNA_primase_lrg PF04104.9 AAS50826.1 - 1.3e-71 240.8 0.0 1.7e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Amino_oxidase PF01593.19 AAS50827.2 - 8.1e-52 176.7 0.2 3.5e-51 174.6 0.2 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 AAS50827.2 - 3.7e-13 49.2 0.2 9.3e-13 48.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AAS50827.2 - 4.4e-07 30.1 0.0 3.2e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AAS50827.2 - 9.8e-07 27.9 3.7 2.8e-05 23.1 3.4 2.0 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.19 AAS50827.2 - 5e-06 25.6 5.1 4.3e-05 22.5 3.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AAS50827.2 - 2.8e-05 23.3 0.9 4.7e-05 22.6 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AAS50827.2 - 0.002 18.0 0.2 0.0044 16.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AAS50827.2 - 0.0038 16.3 0.3 0.0061 15.6 0.2 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 AAS50827.2 - 0.027 12.9 1.0 0.041 12.3 0.7 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 AAS50827.2 - 0.032 13.0 2.3 0.059 12.2 1.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 AAS50827.2 - 0.036 13.6 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 AAS50827.2 - 0.05 13.9 3.1 0.14 12.5 0.7 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 AAS50827.2 - 0.16 12.0 0.2 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 AAS50827.2 - 0.21 10.4 2.5 0.86 8.4 0.7 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Copper-fist PF00649.13 AAS50828.2 - 7.9e-23 79.3 2.6 2.2e-22 77.9 1.8 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain UQ_con PF00179.21 AAS50829.1 - 5e-49 165.3 0.0 5.7e-49 165.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AAS50829.1 - 0.12 12.3 0.9 0.22 11.4 0.5 1.9 1 1 1 2 2 2 0 RWD domain Prok-E2_B PF14461.1 AAS50829.1 - 0.12 12.0 0.2 0.36 10.5 0.1 1.9 2 1 0 2 2 2 0 Prokaryotic E2 family B Glyco_hydro_76 PF03663.9 AAS50830.2 - 1.6e-148 495.0 16.9 2e-148 494.7 11.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF2347 PF09804.4 AAS50831.2 - 8.9e-81 271.2 0.0 1.1e-80 270.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 AAS50831.2 - 6.3e-29 101.3 0.3 1.4e-16 61.0 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) Avl9 PF09794.4 AAS50831.2 - 4.2e-09 35.3 0.0 0.00024 19.7 0.0 2.3 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.5 AAS50831.2 - 4e-06 26.4 0.0 1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis BLOC1_2 PF10046.4 AAS50832.1 - 0.00044 20.3 2.1 0.0027 17.7 0.9 2.0 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dad2 PF08654.5 AAS50832.1 - 0.0034 17.3 1.2 0.025 14.5 0.2 2.4 2 1 0 2 2 2 1 DASH complex subunit Dad2 HrpB7 PF09486.5 AAS50832.1 - 0.04 13.8 1.0 0.11 12.4 0.7 1.6 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF4351 PF14261.1 AAS50832.1 - 0.057 13.3 2.2 0.66 9.8 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) Baculo_PEP_C PF04513.7 AAS50832.1 - 0.064 13.0 0.2 0.68 9.7 0.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF812 PF05667.6 AAS50832.1 - 0.098 11.1 1.9 0.11 10.9 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3610 PF12272.3 AAS50832.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3610) Apolipoprotein PF01442.13 AAS50832.1 - 0.14 11.6 4.6 0.22 10.9 3.2 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DOG1 PF14144.1 AAS50832.1 - 0.15 12.1 0.3 0.36 10.8 0.1 1.8 1 1 1 2 2 2 0 Seed dormancy control SYCE1 PF15233.1 AAS50832.1 - 0.51 10.2 3.8 0.39 10.6 1.3 1.7 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 DUF733 PF05306.6 AAS50832.1 - 0.54 10.5 4.5 0.46 10.8 0.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF733) AKNA PF12443.3 AAS50832.1 - 0.95 9.5 3.5 1.6 8.8 0.2 2.3 1 1 1 2 2 2 0 AT-hook-containing transcription factor TrmE_N PF10396.4 AAS50833.3 - 1.4e-34 118.4 0.0 2.6e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 AAS50833.3 - 1.9e-19 69.7 0.0 3.8e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 AAS50833.3 - 1.4e-16 60.6 0.0 4.2e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 AAS50833.3 - 2e-10 40.1 0.0 3.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 AAS50833.3 - 1.4e-06 27.8 0.0 0.00018 21.0 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AAS50833.3 - 0.00011 22.0 0.4 0.0026 17.5 0.1 2.4 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 AAS50833.3 - 0.00022 21.6 0.0 0.0005 20.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein cobW PF02492.14 AAS50833.3 - 0.0015 17.9 0.1 0.023 14.1 0.0 2.2 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.17 AAS50833.3 - 0.16 11.3 0.0 0.34 10.3 0.0 1.6 1 1 0 1 1 1 0 Ras family AAA_16 PF13191.1 AAS50833.3 - 0.49 10.3 4.2 5 7.0 0.1 3.3 1 1 0 2 2 2 0 AAA ATPase domain dsrm PF00035.20 AAS50835.2 - 3.4e-08 33.9 0.0 6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 AAS50835.2 - 4.2e-07 30.3 0.0 8.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain Met_10 PF02475.11 AAS50836.2 - 0.00084 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MitMem_reg PF13012.1 AAS50836.2 - 0.046 13.8 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Pex2_Pex12 PF04757.9 AAS50837.1 - 3.8e-41 140.9 3.9 4.5e-41 140.7 2.7 1.0 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 AAS50837.1 - 8.8e-07 28.8 2.0 1.6e-06 27.9 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AAS50837.1 - 2.9e-05 23.6 1.4 5.3e-05 22.8 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) APH PF01636.18 AAS50837.1 - 0.0048 16.6 1.7 0.0078 15.9 1.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-C3HC4_4 PF15227.1 AAS50837.1 - 0.0053 16.6 2.7 0.01 15.7 1.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 AAS50837.1 - 0.0076 16.0 1.4 0.016 15.0 1.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AAS50837.1 - 0.019 14.6 0.7 0.031 13.9 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) F_bP_aldolase PF01116.15 AAS50838.2 - 7.6e-97 323.8 0.1 8.6e-97 323.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF89 PF01937.14 AAS50839.1 - 1.4e-114 382.6 0.0 1.6e-114 382.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DWNN PF08783.6 AAS50840.2 - 1.3e-31 108.3 0.1 3.4e-31 107.0 0.0 1.7 2 0 0 2 2 2 1 DWNN domain U-box PF04564.10 AAS50840.2 - 2.4e-05 24.2 0.0 0.00016 21.5 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-CCHC_2 PF13696.1 AAS50840.2 - 0.00064 19.1 4.1 0.0016 17.9 2.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 AAS50840.2 - 0.0029 17.4 4.1 0.0029 17.4 2.8 1.9 2 0 0 2 2 2 1 Zinc knuckle Rubredoxin PF00301.15 AAS50840.2 - 0.0093 15.8 5.5 0.59 10.0 0.1 3.0 3 0 0 3 3 3 2 Rubredoxin zf-CCHC_3 PF13917.1 AAS50840.2 - 0.013 15.2 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Telomere_Sde2_2 PF13297.1 AAS50840.2 - 0.036 13.3 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 Telomere stability C-terminal zf-Nse PF11789.3 AAS50840.2 - 0.037 13.5 0.2 0.1 12.1 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TFIIA_gamma_C PF02751.9 AAS50841.2 - 4e-26 90.5 0.4 5.9e-26 90.0 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 AAS50841.2 - 6.2e-25 86.5 0.2 8.4e-25 86.1 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TAP42 PF04177.7 AAS50842.2 - 9.7e-94 314.0 0.3 1.1e-93 313.9 0.2 1.0 1 0 0 1 1 1 1 TAP42-like family Nup160 PF11715.3 AAS50843.2 - 5.2e-19 67.7 3.2 1.3e-18 66.4 2.2 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Apc3 PF12895.2 AAS50843.2 - 0.0021 18.1 0.8 0.0076 16.3 0.2 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 AAS50843.2 - 0.0036 17.1 0.7 0.012 15.4 0.5 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 AAS50843.2 - 0.0044 16.9 0.7 0.45 10.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 AAS50843.2 - 0.0096 15.5 1.3 0.069 12.8 0.9 2.3 1 1 0 1 1 1 1 TPR repeat DUF3888 PF13027.1 AAS50843.2 - 0.034 13.9 0.1 0.12 12.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) TPR_1 PF00515.23 AAS50843.2 - 0.055 13.1 0.3 0.055 13.1 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 AAS50843.2 - 0.23 11.3 7.2 0.69 9.8 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Striatin PF08232.7 AAS50844.2 - 4e-26 91.9 6.8 5.5e-24 85.0 0.7 2.6 2 1 1 3 3 3 2 Striatin family Herpes_BLRF2 PF05812.7 AAS50844.2 - 0.0088 15.8 0.2 0.022 14.5 0.2 1.6 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein Mto2_bdg PF12808.2 AAS50844.2 - 0.023 14.8 2.3 0.059 13.4 1.6 1.6 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TMF_TATA_bd PF12325.3 AAS50844.2 - 0.28 10.9 2.1 0.43 10.3 0.8 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TCTP PF00838.12 AAS50845.2 - 2e-73 245.8 1.3 2.3e-73 245.6 0.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein NAGidase PF07555.8 AAS50845.2 - 0.099 11.5 0.1 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase adh_short PF00106.20 AAS50846.2 - 5.9e-15 55.5 7.6 1.8e-09 37.7 1.7 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 AAS50846.2 - 8.4e-05 22.4 0.1 0.00031 20.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 AAS50846.2 - 0.03 14.3 0.6 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding UPF0203 PF05254.7 AAS50848.1 - 7.3e-31 105.8 1.4 8.5e-31 105.6 1.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 AAS50848.1 - 0.0013 18.6 2.4 0.0029 17.4 1.6 1.6 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.5 AAS50848.1 - 0.02 14.6 1.8 0.85 9.4 0.0 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Baculo_p74_N PF08404.5 AAS50848.1 - 0.023 13.4 0.3 0.024 13.4 0.2 1.1 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal COX6B PF02297.12 AAS50848.1 - 0.18 11.8 3.7 1.4 8.9 0.1 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DASH_Ask1 PF08655.5 AAS50849.1 - 2.4e-28 97.7 0.3 3.7e-28 97.1 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 Frag1 PF10277.4 AAS50850.2 - 2.2e-79 265.9 23.0 2.5e-79 265.7 15.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MgtE PF01769.11 AAS50850.2 - 8.4 6.6 8.6 3.3 8.0 2.2 2.3 1 1 1 2 2 2 0 Divalent cation transporter DUF3812 PF12757.2 AAS50851.1 - 1.3e-29 102.7 7.3 1.3e-29 102.7 5.1 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3812) FCH PF00611.18 AAS50852.2 - 2.5e-20 72.4 1.4 2.5e-20 72.4 1.0 2.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 AAS50852.2 - 3.2e-08 33.0 0.0 3.1e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 AAS50852.2 - 4.9e-07 29.0 0.0 1.1e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AAS50852.2 - 1.8e-06 27.3 0.0 5.5e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Tropomyosin_1 PF12718.2 AAS50852.2 - 0.011 15.5 5.9 0.011 15.5 4.1 2.4 2 0 0 2 2 2 0 Tropomyosin like SIT PF15330.1 AAS50852.2 - 0.39 10.8 5.2 0.14 12.3 0.8 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Histone PF00125.19 AAS50853.2 - 2.5e-25 88.3 0.9 5.8e-25 87.2 0.6 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 AAS50853.2 - 0.0034 17.5 0.3 0.0097 16.0 0.1 1.8 2 0 0 2 2 2 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AAS50853.2 - 0.11 12.6 0.3 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Actin PF00022.14 AAS50854.1 - 5.5e-21 74.4 0.0 8.4e-19 67.2 0.0 2.7 2 1 0 2 2 2 2 Actin Hydantoinase_A PF01968.13 AAS50854.1 - 0.2 10.7 0.0 0.41 9.6 0.0 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase DUF4137 PF13593.1 AAS50855.2 - 5.7e-109 364.0 17.8 6.7e-109 363.7 12.4 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 AAS50855.2 - 8.2e-08 31.8 9.4 2e-07 30.5 6.4 1.8 1 1 0 1 1 1 1 Sodium Bile acid symporter family Peptidase_S24 PF00717.18 AAS50856.1 - 3.7e-09 36.0 0.0 7.4e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 AAS50856.1 - 8.7e-06 25.3 0.0 0.00045 19.7 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Rhodanese PF00581.15 AAS50857.2 - 9.3e-12 45.3 0.0 2.2e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.20 AAS50858.2 - 2.7e-35 121.7 0.0 1.7e-32 112.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AAS50858.2 - 3.5e-18 65.6 0.0 6.3e-12 45.1 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 AAS50858.2 - 2.3e-06 26.7 0.0 0.039 12.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 AAS50858.2 - 0.0013 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-C2H2 PF00096.21 AAS50859.2 - 9.5e-13 47.6 13.3 5.2e-06 26.4 2.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS50859.2 - 1.2e-09 37.8 16.0 6.4e-05 23.0 2.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AAS50859.2 - 3.1e-08 33.5 19.8 4.3e-07 29.8 2.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AAS50859.2 - 4e-06 26.8 8.7 0.00062 19.8 1.4 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 AAS50859.2 - 0.00022 20.9 6.3 0.022 14.5 0.9 2.4 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_6 PF13912.1 AAS50859.2 - 0.0012 18.6 0.7 0.0012 18.6 0.5 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 AAS50859.2 - 0.08 13.0 6.2 0.39 10.8 0.3 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 AAS50859.2 - 0.11 12.6 5.5 1.1 9.5 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 AAS50859.2 - 0.17 12.0 5.3 0.83 9.8 3.7 2.2 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 AAS50859.2 - 0.18 11.3 2.6 4.8 6.8 0.6 2.5 1 1 1 2 2 2 0 GAGA factor PyrI_C PF02748.10 AAS50859.2 - 0.48 9.8 2.2 0.92 8.9 0.1 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF629 PF04780.7 AAS50859.2 - 1.2 7.5 6.8 0.85 8.0 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) HMA PF00403.21 AAS50861.1 - 4.4e-11 42.7 0.0 7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF59 PF01883.14 AAS50861.1 - 0.0099 15.8 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF59 CorA PF01544.13 AAS50862.2 - 2.7e-39 134.9 6.5 1.9e-22 79.6 1.1 3.3 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein PC4 PF02229.11 AAS50863.2 - 4e-22 77.1 0.1 6.4e-22 76.5 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Aldo_ket_red PF00248.16 AAS50864.1 - 3.2e-51 173.8 0.0 3.9e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Bap31 PF05529.7 AAS50865.2 - 1.9e-42 144.9 8.4 1.7e-41 141.7 5.8 1.9 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like DsbD_2 PF13386.1 AAS50865.2 - 0.063 13.0 0.1 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region NDK PF00334.14 AAS50866.2 - 8.1e-56 187.5 0.0 9.2e-56 187.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PWWP PF00855.12 AAS50867.2 - 4.2e-17 62.1 0.9 9e-17 61.0 0.1 2.0 2 0 0 2 2 2 1 PWWP domain SRF-TF PF00319.13 AAS50868.2 - 8.6e-24 82.5 0.2 1.2e-23 82.0 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) TFIIE-A_C-term PF11521.3 AAS50868.2 - 0.031 14.2 2.2 0.1 12.5 1.5 1.9 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Nucleoporin_FG PF13634.1 AAS50869.2 - 2e-52 176.2 393.4 2.3e-10 40.7 32.3 11.4 1 1 7 8 8 8 4 Nucleoporin FG repeat region Nucleoporin2 PF04096.9 AAS50869.2 - 1.9e-36 124.9 0.0 3e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Swi3 PF07962.7 AAS50871.1 - 1.1e-31 108.3 0.2 1.6e-31 107.7 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 TAP42 PF04177.7 AAS50871.1 - 0.088 11.7 0.5 0.13 11.1 0.4 1.3 1 0 0 1 1 1 0 TAP42-like family BOP1NT PF08145.7 AAS50872.2 - 2.5e-104 348.6 5.4 2.5e-104 348.6 3.8 1.5 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.27 AAS50872.2 - 3e-29 99.7 6.4 5.8e-11 41.8 0.2 7.4 7 1 0 7 7 7 4 WD domain, G-beta repeat DUF287 PF03384.9 AAS50872.2 - 0.0053 16.9 0.1 0.026 14.6 0.1 2.2 1 0 0 1 1 1 1 Drosophila protein of unknown function, DUF287 Colicin_D PF11429.3 AAS50872.2 - 0.094 12.8 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Colicin D Sec7 PF01369.15 AAS50873.2 - 8.7e-36 123.3 0.5 1.5e-35 122.5 0.4 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 AAS50873.2 - 0.00043 20.4 0.2 0.004 17.3 0.0 2.7 2 1 0 2 2 2 1 PH domain PH_9 PF15410.1 AAS50873.2 - 0.0012 18.9 0.1 0.0097 16.0 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PHF5 PF03660.9 AAS50874.1 - 6.1e-51 170.9 11.9 6.8e-51 170.8 8.2 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.8 AAS50874.1 - 5.3 4.5 7.2 4.3 4.8 4.4 1.2 1 1 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_2 PF13639.1 AAS50875.1 - 9e-11 41.4 6.6 9e-11 41.4 4.5 3.0 3 1 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 AAS50875.1 - 7.9e-08 31.9 23.2 3.5e-07 29.8 2.5 2.7 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 AAS50875.1 - 9.6e-08 31.5 22.1 3.9e-06 26.4 2.3 2.7 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AAS50875.1 - 4e-07 29.5 3.5 4e-07 29.5 2.4 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS50875.1 - 1.1e-05 25.4 25.2 1.6e-05 24.7 4.4 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AAS50875.1 - 3.9e-05 23.3 16.3 0.00018 21.3 3.6 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 AAS50875.1 - 5.8e-05 23.1 8.9 5.8e-05 23.1 6.2 3.4 3 2 0 3 3 3 1 RING-H2 zinc finger Nefa_Nip30_N PF10187.4 AAS50875.1 - 0.019 15.1 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 EAV_GS PF01309.13 AAS50875.1 - 0.085 12.3 0.1 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein DZR PF12773.2 AAS50875.1 - 0.35 10.7 10.1 1.8 8.4 4.4 3.3 1 1 2 3 3 3 0 Double zinc ribbon FANCL_C PF11793.3 AAS50875.1 - 3.9 7.5 22.3 8.9 6.3 4.2 3.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 AAS50875.1 - 7.2 6.4 14.4 0.43 10.3 0.6 3.2 2 1 1 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AAS50875.1 - 8.7 6.3 16.6 0.087 12.7 3.0 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Cofilin_ADF PF00241.15 AAS50876.2 - 2.9e-27 95.0 0.0 1.8e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Glyco_hydro_3 PF00933.16 AAS50877.2 - 0.038 12.9 0.1 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain DUF2404 PF10296.4 AAS50878.2 - 4.8e-30 103.5 0.2 9.5e-30 102.5 0.1 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 AAS50878.2 - 7.1e-07 29.3 0.3 4.1e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 AAS50878.2 - 0.0058 16.8 0.0 0.058 13.6 0.0 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain PI3_PI4_kinase PF00454.22 AAS50879.2 - 1.1e-47 162.4 1.0 2.6e-47 161.2 0.2 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 AAS50879.2 - 6.5e-34 116.1 0.8 6.5e-34 116.1 0.6 3.2 4 0 0 4 4 4 1 UME (NUC010) domain FATC PF02260.15 AAS50879.2 - 6.1e-15 54.3 0.4 1.6e-14 53.0 0.3 1.8 1 0 0 1 1 1 1 FATC domain FAT PF02259.18 AAS50879.2 - 2.5e-13 49.7 0.9 1.1e-12 47.7 0.7 2.0 1 1 0 1 1 1 1 FAT domain TPR_11 PF13414.1 AAS50879.2 - 0.24 11.0 7.4 0.33 10.6 1.3 3.6 4 1 0 4 4 4 0 TPR repeat CKS PF01111.14 AAS50880.1 - 3.4e-35 119.6 0.1 4.6e-35 119.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PRMT5 PF05185.11 AAS50881.2 - 1e-150 502.6 0.0 1.5e-150 502.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.1 AAS50881.2 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DIL PF01843.14 AAS50882.2 - 4.4e-14 52.2 4.7 1.3e-06 28.1 0.2 3.2 2 1 1 3 3 3 2 DIL domain Ank_5 PF13857.1 AAS50882.2 - 1.2e-05 25.3 0.2 5e-05 23.4 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 AAS50882.2 - 0.0008 19.7 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AAS50882.2 - 0.0048 17.3 0.0 4.8 7.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF1380 PF07128.7 AAS50882.2 - 0.024 14.4 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1380) Not1 PF04054.10 AAS50883.2 - 3e-147 490.4 6.4 3e-147 490.4 4.4 4.0 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 AAS50883.2 - 3.3e-41 140.4 6.8 3.3e-41 140.4 4.7 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3819) SOBP PF15279.1 AAS50883.2 - 2.6 8.3 37.1 2.8 8.2 15.6 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein PAT1 PF09770.4 AAS50883.2 - 6.3 4.9 92.6 4 5.5 46.2 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 AAS50884.2 - 1.2e-16 60.3 18.2 1.2e-16 60.3 12.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 AAS50884.2 - 0.0093 15.9 4.4 0.03 14.3 0.2 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1228) Hydantoinase_B PF02538.9 AAS50885.1 - 8.2e-211 700.7 0.0 1.1e-210 700.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 AAS50885.1 - 7.5e-93 310.7 0.0 7.5e-93 310.7 0.0 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 AAS50885.1 - 1.7e-54 183.9 0.1 1.5e-52 177.6 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Mso1_Sec1_bdg PF14475.1 AAS50886.2 - 6.6e-17 60.6 0.1 1.2e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 FliD_N PF02465.13 AAS50886.2 - 0.48 10.8 2.7 0.37 11.1 0.6 1.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Saccharop_dh PF03435.13 AAS50887.1 - 2.2e-129 431.8 0.0 2.6e-129 431.5 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 AAS50887.1 - 2.2e-05 24.5 0.1 3.6e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 AAS50887.1 - 0.00032 20.7 2.1 0.00032 20.7 1.4 1.6 2 0 0 2 2 2 1 NADH(P)-binding F420_oxidored PF03807.12 AAS50887.1 - 0.014 15.7 0.5 0.034 14.5 0.4 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 AAS50887.1 - 0.016 15.7 1.3 0.028 14.9 0.4 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 AAS50887.1 - 0.025 14.5 2.3 0.028 14.3 0.5 1.9 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus DUF2325 PF10087.4 AAS50887.1 - 0.05 13.4 0.1 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) NAD_binding_3 PF03447.11 AAS50887.1 - 0.14 12.5 0.7 0.28 11.5 0.5 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Y_phosphatase2 PF03162.8 AAS50888.4 - 4.1e-33 114.0 1.5 2.5e-31 108.2 1.1 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family DUF3750 PF12570.3 AAS50888.4 - 0.02 15.1 0.0 0.63 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3750) NTF2 PF02136.15 AAS50889.2 - 3e-19 69.5 0.0 5.8e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_6 PF14259.1 AAS50889.2 - 3.8e-05 23.5 0.3 0.00023 21.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AAS50889.2 - 0.0015 18.0 0.1 0.004 16.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HC2 PF07382.6 AAS50889.2 - 0.012 15.4 30.8 0.032 14.1 21.4 1.7 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 RRM_5 PF13893.1 AAS50889.2 - 0.015 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 AAS50889.2 - 1.3 7.4 41.8 1.8 6.9 29.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CRT10 PF08728.5 AAS50889.2 - 7.9 4.3 12.0 13 3.5 8.3 1.3 1 0 0 1 1 1 0 CRT10 CAF1 PF04857.15 AAS50890.2 - 1.4e-48 165.5 0.1 1.9e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease NGP1NT PF08153.7 AAS50891.1 - 4.9e-51 172.0 0.0 7.9e-51 171.3 0.0 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 AAS50891.1 - 6.9e-20 71.1 0.0 3.4e-15 56.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 AAS50891.1 - 2.8e-05 23.4 0.0 0.00013 21.2 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AAS50891.1 - 0.00024 20.9 0.1 0.3 10.8 0.0 3.4 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 AAS50891.1 - 0.0009 18.4 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 AAS50891.1 - 0.0015 17.9 0.2 0.36 10.2 0.0 3.3 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 AAS50891.1 - 0.0016 17.6 0.1 0.21 10.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family SusD-like_3 PF14322.1 AAS50891.1 - 0.044 13.8 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Starch-binding associating with outer membrane RRM_1 PF00076.17 AAS50892.1 - 0.0017 17.9 0.0 0.25 10.9 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS50892.1 - 0.0071 16.2 0.0 0.06 13.3 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS50892.1 - 0.0092 15.8 0.0 0.037 13.8 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOR_SNZ PF01680.12 AAS50893.2 - 1.5e-104 348.1 4.3 2.1e-104 347.6 3.0 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 AAS50893.2 - 5.4e-08 32.2 3.0 1.1e-06 27.9 0.1 2.5 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Dus PF01207.12 AAS50893.2 - 0.0047 15.8 0.6 1.4 7.7 0.0 2.8 2 1 1 3 3 3 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 AAS50893.2 - 0.0062 15.8 0.1 0.072 12.3 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein TMP-TENI PF02581.12 AAS50893.2 - 0.0088 15.1 0.6 0.13 11.3 0.1 2.4 2 1 0 2 2 2 1 Thiamine monophosphate synthase/TENI NanE PF04131.9 AAS50893.2 - 0.01 14.8 0.4 0.17 10.8 0.0 2.3 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 AAS50893.2 - 0.011 14.7 0.2 0.03 13.3 0.0 1.8 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase Nitr_red_bet_C PF14711.1 AAS50893.2 - 0.075 12.5 0.0 0.25 10.8 0.0 1.9 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal 1-cysPrx_C PF10417.4 AAS50893.2 - 0.091 12.4 0.4 5.3 6.7 0.0 2.6 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin NMO PF03060.10 AAS50893.2 - 0.13 11.3 3.9 0.33 10.0 2.2 1.9 1 1 1 2 2 2 0 Nitronate monooxygenase SNO PF01174.14 AAS50894.1 - 1.8e-72 242.9 0.0 2.4e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 AAS50894.1 - 7e-10 38.7 0.0 2.5e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 AAS50894.1 - 1.9e-05 24.2 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DUF4066 PF13278.1 AAS50894.1 - 0.011 15.0 0.1 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative amidotransferase DUF4154 PF13689.1 AAS50894.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) Peptidase_S51 PF03575.12 AAS50894.1 - 0.048 13.4 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 Transp_cyt_pur PF02133.10 AAS50895.1 - 4.6e-145 483.5 38.1 5.2e-145 483.3 26.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ABC2_membrane PF01061.19 AAS50896.3 - 1.5e-67 226.8 57.5 3e-36 124.5 14.6 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 AAS50896.3 - 6.2e-40 136.6 0.0 9.1e-19 68.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 AAS50896.3 - 1.2e-39 134.0 1.4 1.5e-32 111.2 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 AAS50896.3 - 4.6e-16 58.7 33.7 3.8e-12 45.9 3.0 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein DUF258 PF03193.11 AAS50896.3 - 3.3e-06 26.3 0.0 0.00015 21.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_trans_N PF14510.1 AAS50896.3 - 5.6e-06 26.3 0.1 3.1e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 AAS50896.3 - 6.2e-06 26.3 0.3 1.2 9.0 0.0 4.5 3 1 1 4 4 4 1 AAA domain cobW PF02492.14 AAS50896.3 - 1.1e-05 25.0 0.5 0.00021 20.7 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 AAS50896.3 - 2.6e-05 24.3 0.0 0.018 15.1 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 AAS50896.3 - 8e-05 22.1 0.0 0.0073 15.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 AAS50896.3 - 0.0002 21.3 0.7 0.18 11.7 0.2 3.2 2 1 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 AAS50896.3 - 0.00057 20.3 0.0 1.7 9.1 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein SMC_N PF02463.14 AAS50896.3 - 0.001 18.3 0.0 0.14 11.4 0.0 3.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 AAS50896.3 - 0.0016 18.0 0.9 0.34 10.5 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 AAS50896.3 - 0.0061 16.0 0.4 0.064 12.7 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 AAS50896.3 - 0.01 16.6 0.0 0.2 12.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 AAS50896.3 - 0.01 15.4 0.3 0.39 10.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 AAS50896.3 - 0.011 15.8 0.0 3 8.0 0.0 3.1 3 0 0 3 3 2 0 RNA helicase AAA_19 PF13245.1 AAS50896.3 - 0.012 15.3 1.3 4 7.2 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain AAA_18 PF13238.1 AAS50896.3 - 0.013 15.8 0.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 AAS50896.3 - 0.013 15.6 0.0 8.5 6.5 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 AAS50896.3 - 0.015 14.7 0.5 0.89 9.0 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 AAS50896.3 - 0.015 14.8 1.5 2.5 7.6 0.2 2.8 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 AAS50896.3 - 0.016 15.1 0.2 0.13 12.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 AAS50896.3 - 0.022 14.7 0.1 0.35 10.8 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 AAS50896.3 - 0.038 13.0 0.0 7.6 5.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.13 AAS50896.3 - 0.048 12.6 0.1 0.15 11.0 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_10 PF12846.2 AAS50896.3 - 0.06 12.7 0.1 0.55 9.6 0.0 2.5 3 0 0 3 3 3 0 AAA-like domain SbcCD_C PF13558.1 AAS50896.3 - 0.06 13.2 0.0 4 7.4 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 AAS50896.3 - 0.072 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AAA_33 PF13671.1 AAS50896.3 - 0.076 12.8 0.0 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DAGK_prokar PF01219.14 AAS50896.3 - 0.083 12.4 3.2 0.23 11.0 2.2 1.7 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase AAA_30 PF13604.1 AAS50896.3 - 0.1 12.1 0.6 5 6.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 AAS50896.3 - 0.21 11.0 1.6 4.9 6.5 0.1 3.1 3 1 0 3 3 2 0 FtsK/SpoIIIE family ABC_ATPase PF09818.4 AAS50896.3 - 0.29 9.6 0.5 0.47 8.9 0.3 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_23 PF13476.1 AAS50896.3 - 0.52 10.5 1.0 1.1 9.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.19 AAS50897.2 - 3e-82 274.8 58.5 3.9e-45 153.5 14.9 3.5 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 AAS50897.2 - 1.1e-37 127.7 0.6 1.7e-33 114.3 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 AAS50897.2 - 3.2e-30 105.2 0.0 3.1e-15 56.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 AAS50897.2 - 3.5e-21 75.0 0.0 8.6e-21 73.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 AAS50897.2 - 3.2e-06 26.6 0.3 0.00018 21.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 AAS50897.2 - 6.1e-06 25.5 0.0 0.0012 18.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 AAS50897.2 - 8.9e-06 24.9 21.0 8.9e-06 24.9 14.5 3.4 2 2 1 3 3 3 1 ABC-2 family transporter protein cobW PF02492.14 AAS50897.2 - 0.00014 21.3 0.5 0.0014 18.0 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 AAS50897.2 - 0.00027 20.9 0.2 0.091 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AAS50897.2 - 0.00046 19.6 0.7 0.014 14.8 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 AAS50897.2 - 0.001 19.0 0.3 0.068 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AAS50897.2 - 0.0029 17.7 0.1 0.48 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AAS50897.2 - 0.0035 17.0 0.9 3.8 7.3 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 AAS50897.2 - 0.0091 15.8 0.1 0.068 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AAS50897.2 - 0.01 16.6 0.0 0.25 12.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 AAS50897.2 - 0.034 14.4 0.0 0.56 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 AAS50897.2 - 0.038 13.1 0.0 1.4 8.1 0.0 2.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 AAS50897.2 - 0.041 13.5 0.5 0.74 9.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 AAS50897.2 - 0.047 13.6 0.0 0.58 10.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.1 AAS50897.2 - 0.07 12.7 0.2 4.8 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 AAS50897.2 - 0.099 12.5 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 AAS50897.2 - 0.24 11.7 3.2 1.4 9.1 0.1 3.0 2 1 1 3 3 3 0 AAA domain WI12 PF07107.6 AAS50898.2 - 0.0033 17.3 0.0 0.045 13.6 0.0 2.3 2 0 0 2 2 2 1 Wound-induced protein WI12 VWA_N PF08399.6 AAS50898.2 - 0.093 13.3 0.2 0.23 12.0 0.1 1.6 1 0 0 1 1 1 0 VWA N-terminal Cation_efflux PF01545.16 AAS50900.2 - 1.9e-79 266.7 8.8 2.3e-79 266.4 6.1 1.1 1 0 0 1 1 1 1 Cation efflux family NicO PF03824.11 AAS50900.2 - 0.00029 20.2 1.2 0.00059 19.2 0.8 1.6 1 0 0 1 1 1 1 High-affinity nickel-transport protein PgpA PF04608.8 AAS50900.2 - 0.54 10.0 4.4 0.93 9.2 0.1 2.3 2 0 0 2 2 2 0 Phosphatidylglycerophosphatase A CHCH PF06747.8 AAS50901.2 - 8.8e-07 28.6 7.9 1.4e-06 28.0 5.5 1.3 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 AAS50901.2 - 4.2e-06 26.8 2.7 5.9e-06 26.3 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) Pet191_N PF10203.4 AAS50901.2 - 0.059 13.4 3.2 0.1 12.6 2.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 AAS50901.2 - 0.12 12.2 3.6 0.38 10.6 2.5 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 AAS50901.2 - 0.32 10.7 5.4 0.56 10.0 0.5 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like TPR_11 PF13414.1 AAS50902.1 - 4.7e-39 131.8 28.6 1.8e-14 53.1 0.1 6.6 4 2 3 7 7 7 7 TPR repeat TPR_16 PF13432.1 AAS50902.1 - 9.2e-21 73.9 27.5 2.2e-05 24.9 0.8 7.4 5 2 4 9 9 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 AAS50902.1 - 5.5e-20 70.0 32.5 3.4e-06 26.4 0.5 11.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_2 PF07719.12 AAS50902.1 - 1.5e-19 68.2 41.3 0.027 14.3 0.3 11.8 10 2 2 12 12 11 6 Tetratricopeptide repeat TPR_17 PF13431.1 AAS50902.1 - 3.5e-16 57.9 12.5 0.0039 17.2 0.0 8.5 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 AAS50902.1 - 1e-15 57.3 18.9 0.0058 16.5 0.0 7.6 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 AAS50902.1 - 1e-12 48.1 25.7 0.00041 20.6 2.6 7.4 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 AAS50902.1 - 6.5e-12 44.9 23.4 0.082 13.5 0.1 9.0 6 3 3 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 AAS50902.1 - 7.5e-07 28.4 26.8 0.0011 18.5 0.2 8.7 9 2 0 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 AAS50902.1 - 1.3e-05 25.2 21.2 0.013 15.6 0.5 5.1 5 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 AAS50902.1 - 0.00044 19.8 14.0 0.99 9.3 0.0 6.6 8 0 0 8 8 6 2 Tetratricopeptide repeat DUF3808 PF10300.4 AAS50902.1 - 0.043 12.3 8.5 0.26 9.7 0.0 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF3808) Exonuc_VII_S PF02609.11 AAS50902.1 - 0.074 12.8 2.7 0.21 11.3 0.5 2.9 2 0 0 2 2 2 0 Exonuclease VII small subunit FAT PF02259.18 AAS50902.1 - 0.097 11.6 4.4 2.4 7.0 0.0 3.3 3 0 0 3 3 3 0 FAT domain TPR_20 PF14561.1 AAS50902.1 - 0.24 11.5 15.3 0.61 10.2 0.6 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TOM20_plant PF06552.7 AAS50902.1 - 0.26 10.8 14.9 6 6.4 0.1 4.7 3 1 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_6 PF13174.1 AAS50902.1 - 0.69 10.4 28.8 8.2 7.1 0.1 9.5 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_10 PF13374.1 AAS50902.1 - 0.75 9.8 5.9 12 6.0 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat PTS_IIA PF02255.11 AAS50902.1 - 0.9 9.4 6.2 10 6.0 0.3 4.2 4 0 0 4 4 4 0 PTS system, Lactose/Cellobiose specific IIA subunit Cut8_N PF14482.1 AAS50903.1 - 2.3 8.2 0.0 2.3 8.2 0.0 3.1 3 1 0 3 3 3 0 Cut8 proteasome-binding domain Ribosomal_L35p PF01632.14 AAS50904.1 - 1.5e-09 37.6 5.4 2e-09 37.1 3.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 PDZ_1 PF12812.2 AAS50905.2 - 2.6e-53 177.8 0.4 1.3e-34 117.9 0.0 3.7 3 0 0 3 3 3 2 PDZ-like domain PDZ PF00595.19 AAS50905.2 - 5.5e-14 52.1 0.1 5.5e-09 36.0 0.0 3.6 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 AAS50905.2 - 1.7e-13 50.2 1.1 7.2e-05 22.6 0.0 4.1 4 0 0 4 4 4 2 PDZ domain Trypsin_2 PF13365.1 AAS50905.2 - 6.7e-11 42.2 0.3 3.9e-10 39.7 0.0 2.3 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 AAS50905.2 - 1.8e-05 24.4 0.0 9.9e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 Trypsin Tricorn_PDZ PF14685.1 AAS50905.2 - 0.00066 19.4 0.4 0.044 13.5 0.0 2.8 2 0 0 2 2 2 1 Tricorn protease PDZ domain DUF31 PF01732.11 AAS50905.2 - 0.014 14.7 0.1 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Ribosomal_S9 PF00380.14 AAS50905.2 - 0.022 14.9 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Peptidase_S7 PF00949.16 AAS50905.2 - 0.053 12.9 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease ORC6 PF05460.8 AAS50906.1 - 6.6e-107 357.6 0.0 8e-107 357.3 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) N-SET PF11764.3 AAS50907.2 - 2e-48 164.4 2.3 2e-48 164.4 1.6 2.9 4 0 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 AAS50907.2 - 1.9e-25 90.0 0.5 3.9e-23 82.5 0.0 3.2 2 1 0 2 2 2 1 SET domain SET_assoc PF11767.3 AAS50907.2 - 1.2e-22 78.9 1.7 2.2e-22 78.1 0.3 2.1 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated HeLo PF14479.1 AAS50907.2 - 0.9 9.2 5.6 0.15 11.7 0.4 2.3 2 0 0 2 2 2 0 Prion-inhibition and propagation MutS_V PF00488.16 AAS50908.2 - 5.4e-77 258.3 0.0 9.5e-77 257.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AAS50908.2 - 7e-36 123.9 1.3 1.6e-35 122.7 0.9 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 AAS50908.2 - 1.2e-30 105.8 0.0 6.4e-30 103.4 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 AAS50908.2 - 8.3e-10 38.8 0.0 1.9e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_14 PF13173.1 AAS50908.2 - 0.07 13.0 0.0 0.34 10.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AAS50908.2 - 0.071 13.4 0.3 13 6.0 0.0 3.3 3 0 0 3 3 3 0 ABC transporter RSS_P20 PF11757.3 AAS50908.2 - 0.11 12.6 0.2 0.73 9.9 0.0 2.4 2 1 0 2 2 2 0 Suppressor of RNA silencing P21-like Gar1 PF04410.9 AAS50909.2 - 1.8e-45 154.1 0.3 1.8e-45 154.1 0.2 1.7 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region PAT1 PF09770.4 AAS50909.2 - 3.3 5.8 54.0 5.9 4.9 37.5 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA PF00004.24 AAS50910.2 - 1.2e-50 171.1 0.0 1.8e-42 144.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 AAS50910.2 - 3.7e-07 30.2 0.0 0.03 14.3 0.0 2.8 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_2 PF07724.9 AAS50910.2 - 4e-06 26.8 0.0 1.2e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 AAS50910.2 - 4.1e-06 26.3 0.0 0.00013 21.4 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.9 AAS50910.2 - 1.6e-05 24.6 0.0 9e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AAS50910.2 - 2e-05 24.6 0.0 0.00029 20.8 0.0 2.8 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 AAS50910.2 - 2.9e-05 24.2 0.3 0.0015 18.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain Bromodomain PF00439.20 AAS50910.2 - 9.3e-05 22.2 0.1 0.00034 20.4 0.0 1.9 1 0 0 1 1 1 1 Bromodomain Parvo_NS1 PF01057.12 AAS50910.2 - 0.00062 18.7 0.0 0.1 11.4 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 AAS50910.2 - 0.00091 18.7 0.0 0.69 9.3 0.0 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 AAS50910.2 - 0.0013 18.5 0.0 0.012 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AAS50910.2 - 0.0015 17.9 0.1 0.0052 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 AAS50910.2 - 0.0016 18.5 0.0 0.0063 16.6 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 AAS50910.2 - 0.0019 17.8 0.0 0.046 13.4 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 AAS50910.2 - 0.0026 18.5 7.7 0.033 14.9 0.0 4.3 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.22 AAS50910.2 - 0.0044 17.3 0.1 0.043 14.1 0.0 2.7 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.16 AAS50910.2 - 0.0069 15.5 0.1 0.059 12.5 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 AAS50910.2 - 0.012 14.3 0.0 0.026 13.2 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus RuvB_N PF05496.7 AAS50910.2 - 0.021 13.8 0.0 0.049 12.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 AAS50910.2 - 0.025 13.8 0.0 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.6 AAS50910.2 - 0.055 13.0 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 AAS50910.2 - 0.12 11.9 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Amidase PF01425.16 AAS50911.2 - 4.6e-115 384.9 0.0 5.6e-115 384.6 0.0 1.0 1 0 0 1 1 1 1 Amidase Dynamitin PF04912.9 AAS50912.2 - 5.5e-18 64.9 5.0 5.5e-18 64.9 3.5 3.0 2 1 1 3 3 3 1 Dynamitin DUF2408 PF10303.4 AAS50912.2 - 0.001 19.1 7.9 1.7 8.7 0.2 3.9 2 2 2 4 4 4 2 Protein of unknown function (DUF2408) DUF948 PF06103.6 AAS50912.2 - 0.0036 17.1 1.3 0.036 13.9 0.2 2.8 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.4 AAS50912.2 - 0.0036 17.4 0.6 0.0036 17.4 0.4 3.4 4 1 0 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 AAS50912.2 - 0.02 14.0 4.5 0.6 9.2 0.3 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Nsp1_C PF05064.8 AAS50912.2 - 0.021 14.4 0.3 0.021 14.4 0.2 3.3 3 1 0 3 3 3 0 Nsp1-like C-terminal region NPV_P10 PF05531.7 AAS50912.2 - 0.029 14.6 4.9 18 5.6 2.2 4.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DNA_ligase_A_N PF04675.9 AAS50912.2 - 0.081 12.7 2.6 0.14 11.9 0.4 2.0 2 0 0 2 2 2 0 DNA ligase N terminus Baculo_PEP_C PF04513.7 AAS50912.2 - 0.12 12.1 4.6 1.1 9.0 0.4 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hemerythrin PF01814.18 AAS50912.2 - 0.28 11.3 0.1 0.28 11.3 0.1 2.6 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain RPN7 PF10602.4 AAS50912.2 - 0.36 10.1 4.6 0.16 11.3 0.1 2.5 2 1 1 3 3 3 0 26S proteasome subunit RPN7 YlbD_coat PF14071.1 AAS50912.2 - 0.36 10.8 3.6 0.8 9.7 0.9 2.6 1 1 1 2 2 2 0 Putative coat protein Occludin_ELL PF07303.8 AAS50912.2 - 0.37 11.5 9.6 1.7 9.4 0.3 3.8 2 1 2 4 4 4 0 Occludin homology domain Muted PF14942.1 AAS50912.2 - 0.5 10.2 11.7 0.034 14.0 1.4 3.2 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein ACCA PF03255.9 AAS50912.2 - 0.54 9.7 6.5 9.9 5.7 0.1 3.9 2 1 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ATG16 PF08614.6 AAS50912.2 - 0.67 9.7 13.0 0.84 9.4 2.8 3.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) WXG100 PF06013.7 AAS50912.2 - 0.7 9.9 8.7 1.2 9.1 1.6 3.8 3 2 1 4 4 4 0 Proteins of 100 residues with WXG Fib_alpha PF08702.5 AAS50912.2 - 1 9.4 8.4 1.4 8.9 0.4 3.5 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 AAS50912.2 - 1.9 8.3 23.7 0.2 11.4 0.6 4.3 2 1 3 5 5 5 0 Tropomyosin like FUSC PF04632.7 AAS50912.2 - 2 6.7 9.4 2.9 6.1 0.1 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Resolvase PF00239.16 AAS50912.2 - 6.3 6.6 10.0 0.74 9.6 1.1 3.1 2 2 0 2 2 2 0 Resolvase, N terminal domain Sec63 PF02889.11 AAS50913.2 - 2e-134 447.7 0.0 2.5e-91 306.2 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 AAS50913.2 - 1.6e-54 183.9 0.6 3.4e-29 101.5 0.2 4.1 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 AAS50913.2 - 6.7e-22 78.2 0.0 4.4e-10 39.6 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AAS50913.2 - 2.1e-17 62.7 0.0 7.1e-08 32.2 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 AAS50913.2 - 2.9e-06 26.3 0.0 0.0018 17.1 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA PF00004.24 AAS50913.2 - 1.5e-05 25.2 2.1 0.36 11.0 0.0 4.3 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 AAS50913.2 - 0.00011 21.6 0.0 1 8.7 0.0 4.0 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_22 PF13401.1 AAS50913.2 - 0.00012 22.2 5.0 0.19 11.8 0.1 4.4 3 2 0 3 3 3 2 AAA domain PhoH PF02562.11 AAS50913.2 - 0.00022 20.5 0.0 0.23 10.6 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Zeta_toxin PF06414.7 AAS50913.2 - 0.0012 17.9 0.0 0.099 11.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin T2SE PF00437.15 AAS50913.2 - 0.016 14.1 0.0 3.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 AAS50913.2 - 0.016 14.6 0.0 26 4.1 0.0 3.8 3 1 0 4 4 4 0 AAA-like domain DUF2361 PF10153.4 AAS50914.3 - 1.8e-36 124.7 9.9 1.8e-36 124.7 6.9 1.6 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) DUF2406 PF10295.4 AAS50915.1 - 7e-27 93.7 0.1 1.6e-26 92.6 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Aminotran_1_2 PF00155.16 AAS50916.2 - 7.4e-56 189.6 0.0 9.6e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_M16_C PF05193.16 AAS50917.2 - 7.8e-28 97.3 0.0 1.4e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AAS50917.2 - 1.6e-16 60.4 0.7 4.1e-16 59.0 0.5 1.8 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) PPP4R2 PF09184.6 AAS50918.2 - 1.8e-58 198.3 12.6 9.3e-55 186.1 0.0 2.1 1 1 1 2 2 2 1 PPP4R2 TFIIF_alpha PF05793.7 AAS50918.2 - 0.26 9.6 17.1 0.35 9.1 11.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.7 AAS50918.2 - 1 8.5 14.7 1.4 8.1 10.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 AAS50918.2 - 2.4 5.9 16.3 3.2 5.5 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 AAS50918.2 - 3.3 6.0 16.6 4.1 5.7 11.5 1.1 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 AAS50918.2 - 9.6 5.1 12.0 13 4.7 8.3 1.1 1 0 0 1 1 1 0 BUD22 Ribosomal_S7 PF00177.16 AAS50919.2 - 2e-31 108.5 0.1 3.6e-31 107.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e VanZ PF04892.7 AAS50920.2 - 8.7e-06 25.7 0.0 1.6e-05 24.8 0.0 1.4 2 0 0 2 2 2 1 VanZ like family EF-hand_4 PF12763.2 AAS50921.2 - 4.2e-28 97.1 0.0 1.6e-08 34.1 0.0 4.0 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 AAS50921.2 - 1.2e-10 41.3 0.0 0.004 17.2 0.0 4.2 3 1 0 3 3 2 2 EF-hand domain pair UBA PF00627.26 AAS50921.2 - 4.2e-08 32.7 0.3 1.3e-07 31.2 0.2 1.9 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 AAS50921.2 - 1.6e-07 30.1 0.2 0.02 14.1 0.0 4.4 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 AAS50921.2 - 4.2e-07 29.3 0.6 0.1 12.5 0.0 4.6 4 0 0 4 4 4 1 EF-hand domain UBA_4 PF14555.1 AAS50921.2 - 3.4e-05 23.2 0.3 0.0002 20.8 0.0 2.3 2 0 0 2 2 2 1 UBA-like domain Tropomyosin_1 PF12718.2 AAS50921.2 - 0.0002 21.2 19.6 0.0002 21.2 13.6 4.0 1 1 2 3 3 3 1 Tropomyosin like EF-hand_8 PF13833.1 AAS50921.2 - 0.0016 18.0 0.1 19 4.9 0.0 3.9 3 1 0 3 3 3 0 EF-hand domain pair IncA PF04156.9 AAS50921.2 - 0.0067 16.0 69.3 0.54 9.8 10.4 3.5 1 1 2 3 3 3 2 IncA protein CUE PF02845.11 AAS50921.2 - 0.01 15.2 0.7 0.11 11.9 0.0 3.0 3 0 0 3 3 3 0 CUE domain Filament PF00038.16 AAS50921.2 - 0.088 12.2 52.2 0.49 9.8 13.3 2.7 2 0 0 2 2 2 0 Intermediate filament protein DUF3584 PF12128.3 AAS50921.2 - 1.3 6.2 59.7 4.7 4.4 41.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4200 PF13863.1 AAS50921.2 - 1.6 8.6 57.8 0.1 12.5 10.8 4.5 1 1 2 4 4 4 0 Domain of unknown function (DUF4200) AAA_13 PF13166.1 AAS50921.2 - 1.9 6.8 46.8 0.52 8.6 20.3 2.7 1 1 2 3 3 3 0 AAA domain Spc7 PF08317.6 AAS50921.2 - 3.9 6.0 55.2 3.1 6.3 13.4 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein Tropomyosin PF00261.15 AAS50921.2 - 4.6 6.2 57.9 0.2 10.7 21.8 4.1 2 1 2 4 4 4 0 Tropomyosin Nnf1 PF03980.9 AAS50922.1 - 3.1e-31 107.6 1.9 3.1e-31 107.6 1.3 2.0 1 1 1 2 2 2 1 Nnf1 bZIP_1 PF00170.16 AAS50922.1 - 0.0053 16.6 3.0 0.0053 16.6 2.1 2.7 3 0 0 3 3 3 1 bZIP transcription factor TMF_TATA_bd PF12325.3 AAS50922.1 - 0.021 14.5 0.1 0.047 13.4 0.1 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding KfrA_N PF11740.3 AAS50922.1 - 0.048 14.0 3.6 0.056 13.8 1.8 1.7 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF4298 PF14131.1 AAS50922.1 - 0.067 13.0 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) DUF342 PF03961.8 AAS50922.1 - 0.39 9.0 1.9 0.56 8.5 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mto2_bdg PF12808.2 AAS50922.1 - 0.44 10.6 6.8 0.78 9.8 2.0 2.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4140 PF13600.1 AAS50922.1 - 0.62 10.5 3.4 0.61 10.5 1.0 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Kinetocho_Slk19 PF12709.2 AAS50922.1 - 0.65 10.1 3.4 0.37 10.9 0.7 1.8 2 0 0 2 2 2 0 Central kinetochore-associated Mst1_SARAH PF11629.3 AAS50922.1 - 0.96 9.3 4.6 10 6.0 3.2 2.4 1 1 0 1 1 1 0 C terminal SARAH domain of Mst1 LXG PF04740.7 AAS50922.1 - 1.1 9.0 3.2 8.7 6.0 0.8 2.5 2 1 0 2 2 2 0 LXG domain of WXG superfamily IncA PF04156.9 AAS50922.1 - 1.8 8.1 11.6 0.15 11.6 2.3 2.4 1 1 0 2 2 2 0 IncA protein ADIP PF11559.3 AAS50922.1 - 5.2 6.9 9.9 1.2 9.0 3.7 2.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4404 PF14357.1 AAS50922.1 - 7.4 7.0 8.5 0.94 9.9 1.8 2.3 3 0 0 3 3 2 0 Domain of unknown function (DUF4404) CMD PF02627.15 AAS50923.1 - 0.00035 20.3 1.4 0.0026 17.5 0.0 2.9 4 0 0 4 4 4 1 Carboxymuconolactone decarboxylase family Myotub-related PF06602.9 AAS50924.2 - 1.1e-132 442.0 0.4 1.5e-132 441.7 0.3 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 AAS50924.2 - 0.0029 17.8 0.0 0.0062 16.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 AAS50924.2 - 0.0044 16.3 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 AAS50924.2 - 0.006 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain GRAM PF02893.15 AAS50924.2 - 0.081 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 GRAM domain Yippee-Mis18 PF03226.9 AAS50925.1 - 1.8e-17 63.1 2.7 2.4e-17 62.7 1.9 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly LIM PF00412.17 AAS50925.1 - 0.023 14.7 2.6 0.28 11.2 0.0 2.3 2 0 0 2 2 2 0 LIM domain Inhibitor_I67 PF11405.3 AAS50925.1 - 0.21 11.6 0.4 0.21 11.6 0.3 2.2 3 0 0 3 3 3 0 Bromelain inhibitor VI NAD_binding_6 PF08030.7 AAS50926.1 - 4.1e-20 72.2 0.0 6.9e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 AAS50926.1 - 2e-18 66.1 0.0 3.9e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 AAS50926.1 - 7.4e-17 61.6 16.0 2e-15 56.9 9.8 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component SNAP PF14938.1 AAS50927.1 - 8.5e-106 353.2 13.7 9.6e-106 353.0 9.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 AAS50927.1 - 0.00013 22.1 8.3 4.5 7.9 0.0 5.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 AAS50927.1 - 0.00049 19.6 18.2 0.0078 15.8 1.0 3.5 2 2 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 AAS50927.1 - 0.021 14.7 22.6 0.083 12.8 0.5 4.2 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 AAS50927.1 - 0.027 14.8 0.4 0.027 14.8 0.3 4.1 2 1 1 4 4 4 0 Tetratricopeptide repeat Rapamycin_bind PF08771.6 AAS50927.1 - 0.038 14.0 0.1 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Rapamycin binding domain ASD2 PF08687.6 AAS50927.1 - 0.061 12.6 0.2 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Foie-gras_1 PF11817.3 AAS50927.1 - 0.25 10.7 3.4 5.8 6.3 0.1 2.8 2 1 0 3 3 3 0 Foie gras liver health family 1 TPR_14 PF13428.1 AAS50927.1 - 4.2 8.2 11.0 19 6.2 0.1 4.9 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 AAS50927.1 - 8.5 7.1 19.4 10 6.9 2.5 4.1 2 1 3 5 5 5 0 Tetratricopeptide repeat OPT PF03169.10 AAS50928.2 - 4e-181 603.6 60.5 4.6e-181 603.4 41.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CPSase_L_D2 PF02786.12 AAS50929.2 - 3.5e-108 359.7 0.0 3.6e-83 278.0 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 AAS50929.2 - 1.3e-40 137.8 0.0 6.7e-19 68.0 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 AAS50929.2 - 1.1e-38 132.8 0.0 1.3e-22 80.4 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_D3 PF02787.14 AAS50929.2 - 9.5e-37 125.4 0.0 1.9e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATPgrasp_Ter PF15632.1 AAS50929.2 - 3.7e-23 81.7 0.0 3.8e-10 39.0 0.0 3.5 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AAS50929.2 - 8.8e-18 64.2 0.0 1.1e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AAS50929.2 - 1.1e-12 47.7 0.0 6.4e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 AAS50929.2 - 9.7e-06 25.1 0.0 0.0075 15.7 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain MGS PF02142.17 AAS50929.2 - 5.4e-05 23.0 0.0 0.00018 21.3 0.0 1.9 1 0 0 1 1 1 1 MGS-like domain ATP-grasp_5 PF13549.1 AAS50929.2 - 0.012 14.8 0.0 0.044 12.9 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain Epimerase PF01370.16 AAS50929.2 - 0.07 12.5 0.0 4 6.8 0.0 2.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family UPF0180 PF03698.8 AAS50929.2 - 0.084 12.7 0.0 28 4.6 0.0 3.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) G-alpha PF00503.15 AAS50930.1 - 4.3e-110 368.0 0.0 4.5e-110 367.9 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 AAS50930.1 - 6.2e-14 51.6 0.6 2.5e-09 36.6 0.2 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 AAS50930.1 - 0.00015 22.2 0.1 0.8 10.2 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 AAS50930.1 - 0.0017 17.5 0.8 0.22 10.6 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AAS50930.1 - 0.059 13.3 0.3 1.3 9.0 0.2 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 AAS50930.1 - 0.083 12.4 0.1 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 AAS50930.1 - 0.11 11.9 0.2 1 8.7 0.2 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Lipase_3 PF01764.20 AAS50931.1 - 1e-38 132.1 0.0 1.6e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 AAS50931.1 - 0.099 12.3 0.0 0.51 10.0 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Na_Ca_ex PF01699.19 AAS50932.1 - 6.2e-44 148.9 36.0 5.1e-27 94.1 5.2 3.0 3 1 0 3 3 3 2 Sodium/calcium exchanger protein PfkB PF00294.19 AAS50933.1 - 4.8e-70 236.0 0.0 6.3e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 AAS50933.1 - 0.00053 19.2 0.0 0.0015 17.7 0.0 1.7 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TRAM_LAG1_CLN8 PF03798.11 AAS50934.1 - 2.2e-27 95.9 14.8 3.5e-27 95.2 10.3 1.3 1 0 0 1 1 1 1 TLC domain Peptidase_M48 PF01435.13 AAS50935.1 - 2.6e-40 138.3 0.0 4e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Herpes_LMP1 PF05297.6 AAS50935.1 - 1.1 8.0 4.1 2 7.2 2.8 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Rpn3_C PF08375.6 AAS50936.1 - 4.8e-22 78.1 1.8 7.2e-22 77.5 0.5 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 AAS50936.1 - 3.2e-20 72.3 1.5 8.3e-20 71.0 0.1 2.3 2 0 0 2 2 2 1 PCI domain MarR_2 PF12802.2 AAS50936.1 - 0.0084 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 MarR family PCI_Csn8 PF10075.4 AAS50936.1 - 0.009 15.7 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 FeoC PF09012.5 AAS50936.1 - 0.13 11.9 0.1 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator TPR_2 PF07719.12 AAS50936.1 - 0.14 12.1 1.6 9.9 6.3 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Med17 PF10156.4 AAS50937.1 - 6.3e-147 489.6 7.3 7.7e-147 489.3 5.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Ilm1 PF10311.4 AAS50938.2 - 1.9e-42 144.5 9.7 2.6e-42 144.1 6.7 1.2 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF4293 PF14126.1 AAS50938.2 - 0.4 10.6 4.6 1.4 8.8 3.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) JmjC PF02373.17 AAS50939.1 - 9.3e-40 135.4 0.6 2.2e-39 134.2 0.4 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 AAS50939.1 - 2.8e-12 45.9 0.0 6.3e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 AAS50939.1 - 1.3e-08 34.3 7.2 1.3e-08 34.3 5.0 2.3 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 AAS50939.1 - 0.0026 17.5 8.3 0.0065 16.2 4.7 2.5 2 0 0 2 2 2 1 Ring finger domain Prok-RING_1 PF14446.1 AAS50939.1 - 0.0029 17.3 4.7 0.0029 17.3 3.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 AAS50939.1 - 0.0038 16.4 3.0 0.0038 16.4 2.0 2.7 2 0 0 2 2 2 1 PHD-finger FYVE_2 PF02318.11 AAS50939.1 - 0.02 14.7 3.1 0.051 13.4 2.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Tet_JBP PF12851.2 AAS50939.1 - 0.092 12.0 0.2 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily zf-HC5HC2H PF13771.1 AAS50939.1 - 0.35 11.0 7.8 0.039 14.1 2.1 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain DUF2616 PF11077.3 AAS50939.1 - 1 8.8 10.3 0.038 13.4 2.6 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) P5CR_dimer PF14748.1 AAS50940.1 - 3e-33 114.0 2.0 3.5e-33 113.8 0.5 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 AAS50940.1 - 4e-12 46.4 0.1 1.2e-11 44.8 0.1 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 AAS50940.1 - 0.0064 16.2 0.2 0.012 15.3 0.2 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DapB_N PF01113.15 AAS50940.1 - 0.012 15.5 0.3 0.31 10.9 0.2 2.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PDH PF02153.12 AAS50940.1 - 0.094 11.5 0.3 1.3 7.8 0.1 2.5 1 1 2 3 3 3 0 Prephenate dehydrogenase ATP-synt_ab PF00006.20 AAS50941.2 - 6.1e-63 212.1 0.0 9.6e-63 211.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AAS50941.2 - 1.3e-26 93.2 0.3 2.4e-26 92.3 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AAS50941.2 - 1.2e-24 86.2 3.1 3.5e-24 84.8 2.1 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 AAS50941.2 - 0.00072 18.7 0.1 0.0014 17.8 0.1 1.5 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 AAS50941.2 - 0.0053 16.1 0.0 0.017 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 AAS50941.2 - 0.0081 15.8 0.1 0.53 9.9 0.0 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 AAS50941.2 - 0.011 14.6 0.8 0.52 9.1 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 AAS50941.2 - 0.023 14.3 0.1 0.067 12.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 AAS50941.2 - 0.034 14.1 0.3 0.2 11.6 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 AAS50941.2 - 0.04 14.1 0.0 0.55 10.4 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 AAS50941.2 - 0.055 12.6 0.1 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 AAS50941.2 - 0.088 12.9 0.0 0.37 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AAS50941.2 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 AAS50941.2 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase GCV_T PF01571.16 AAS50942.1 - 4.3e-08 32.7 0.0 0.0054 16.1 0.0 2.9 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 AAS50942.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Ribosomal_S7 PF00177.16 AAS50943.1 - 2e-39 134.5 1.9 2.6e-39 134.1 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Carn_acyltransf PF00755.15 AAS50944.2 - 5.7e-71 239.3 0.0 2.3e-60 204.3 0.1 2.1 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase MFS_1 PF07690.11 AAS50945.2 - 9.3e-32 110.0 52.1 3.5e-23 81.8 17.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AAS50945.2 - 1.2e-13 50.3 21.2 1e-10 40.5 4.2 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein ATG22 PF11700.3 AAS50945.2 - 3.2e-06 25.9 3.3 3.2e-06 25.9 2.3 2.9 2 1 0 3 3 3 1 Vacuole effluxer Atg22 like OATP PF03137.15 AAS50945.2 - 0.0017 16.5 0.5 0.0017 16.5 0.4 2.8 4 1 0 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 AAS50945.2 - 0.0025 16.4 21.1 0.062 11.8 14.6 3.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 AAS50945.2 - 0.084 12.6 5.5 0.16 11.8 0.1 3.7 4 0 0 4 4 4 0 MFS_1 like family Zn_clus PF00172.13 AAS50946.2 - 5.9e-09 35.6 10.7 1.2e-08 34.7 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AAS50946.2 - 1e-07 31.0 0.6 2e-07 30.1 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GTP_EFTU PF00009.22 AAS50947.2 - 6.6e-39 133.2 0.0 1.1e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 AAS50947.2 - 1.9e-36 123.9 0.2 4e-36 122.9 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 AAS50947.2 - 7.4e-11 42.0 0.3 2.9e-10 40.1 0.2 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AAS50947.2 - 0.0057 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AAS50947.2 - 0.12 12.2 0.1 0.79 9.5 0.1 2.3 1 1 0 1 1 1 0 Dynamin family RGS PF00615.14 AAS50948.2 - 4.1e-18 65.5 0.2 3e-10 40.2 0.1 2.6 2 0 0 2 2 2 2 Regulator of G protein signaling domain DEP PF00610.16 AAS50948.2 - 5.1e-12 45.3 0.0 1.4e-10 40.7 0.0 2.6 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.20 AAS50949.1 - 5.2e-74 248.6 0.0 7.2e-74 248.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS50949.1 - 4.1e-32 111.2 0.1 3.2e-31 108.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS50949.1 - 0.0071 15.3 0.0 0.017 14.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like ORC4_C PF14629.1 AAS50950.1 - 1e-29 103.4 2.3 3.6e-29 101.5 0.6 2.1 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 AAS50950.1 - 4.7e-05 23.4 1.3 0.00054 20.0 0.2 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.24 AAS50950.1 - 0.042 14.0 0.9 0.089 12.9 0.1 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RRM_6 PF14259.1 AAS50951.2 - 1.6e-08 34.3 0.0 2.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AAS50951.2 - 4.1e-07 29.5 0.0 7.8e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fmp27 PF10344.4 AAS50952.2 - 1.9e-181 604.9 17.3 3.3e-181 604.1 12.0 1.4 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.4 AAS50952.2 - 3.2e-129 431.4 3.1 5e-129 430.8 2.1 1.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 AAS50952.2 - 4.3e-107 358.8 11.2 8.4e-107 357.8 7.7 1.5 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 AAS50952.2 - 3.3e-56 189.5 1.2 1.2e-55 187.7 0.0 2.5 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 AAS50952.2 - 5.6e-54 182.1 1.4 1.3e-53 180.9 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 AAS50952.2 - 4.9e-32 110.4 0.1 5.6e-31 107.0 0.0 3.1 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Ras PF00071.17 AAS50954.1 - 8.9e-54 181.2 0.0 1e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS50954.1 - 1.2e-14 54.7 0.0 1.9e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS50954.1 - 4.2e-08 32.6 0.0 6.6e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AAS50954.1 - 0.11 11.6 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.17 AAS50955.1 - 3e-55 186.0 0.0 3.6e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS50955.1 - 1.9e-16 60.6 0.0 3.3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS50955.1 - 6.9e-07 28.6 0.0 1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AAS50955.1 - 6.3e-05 22.4 0.0 0.00027 20.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AAS50955.1 - 0.015 14.4 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S14 PF00253.16 AAS50956.1 - 1.5e-19 69.1 0.1 2.5e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e NinG PF05766.7 AAS50956.1 - 0.051 13.3 0.1 0.064 12.9 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Pantoate_transf PF02548.10 AAS50958.1 - 3.6e-99 331.1 0.1 4.3e-99 330.8 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 AAS50958.1 - 1.5e-05 24.3 0.2 7.4e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Lactamase_B_2 PF12706.2 AAS50959.1 - 2.4e-32 112.0 0.0 3.1e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AAS50959.1 - 9.1e-09 35.2 0.1 1.6e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AAS50959.1 - 0.12 11.9 0.1 0.84 9.2 0.0 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily PAXNEB PF05625.6 AAS50960.2 - 5.5e-98 328.1 0.0 7.3e-98 327.7 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein WD40 PF00400.27 AAS50961.2 - 2.8e-07 30.1 1.6 0.00061 19.5 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AAS50961.2 - 1.1e-06 27.7 0.3 0.016 13.9 0.3 2.5 1 1 1 2 2 2 2 Nup133 N terminal like Lactonase PF10282.4 AAS50961.2 - 0.00031 19.9 0.0 0.0018 17.4 0.0 2.0 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SieB PF14163.1 AAS50962.2 - 0.1 12.1 0.7 0.32 10.5 0.3 1.8 2 0 0 2 2 2 0 Superinfection exclusion protein B RPEL PF02755.10 AAS50962.2 - 0.18 11.1 0.9 0.39 10.1 0.6 1.6 1 0 0 1 1 1 0 RPEL repeat Romo1 PF10247.4 AAS50963.1 - 4.2e-28 97.3 5.6 5.3e-28 97.0 3.9 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 tRNA-synt_1b PF00579.20 AAS50964.2 - 8.7e-73 244.9 0.0 1e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ion_trans PF00520.26 AAS50965.1 - 0.03 13.5 2.1 0.058 12.6 0.2 1.9 1 1 1 2 2 2 0 Ion transport protein Rad4 PF03835.10 AAS50966.1 - 4e-15 55.4 0.9 7.3e-15 54.6 0.6 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 AAS50966.1 - 1.9e-11 44.1 0.4 3.3e-11 43.4 0.2 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily zf-B_box PF00643.19 AAS50966.1 - 4.4 7.2 6.0 7.2 6.5 0.2 2.8 1 1 1 2 2 2 0 B-box zinc finger Abhydrolase_1 PF00561.15 AAS50967.1 - 6.3e-18 65.1 0.0 1.4e-17 64.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AAS50967.1 - 9.5e-13 48.5 0.0 1.9e-12 47.5 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AAS50967.1 - 1.5e-05 24.7 0.0 5.9e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Dynamin_N PF00350.18 AAS50968.2 - 1.3e-17 64.1 0.2 3.6e-17 62.6 0.1 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 AAS50968.2 - 2.6e-10 40.2 0.1 1.3e-09 38.0 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AAS50968.2 - 1.1e-09 37.9 1.7 5.6e-09 35.7 1.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.14 AAS50968.2 - 0.0014 18.1 0.1 0.16 11.4 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 AAS50968.2 - 0.0027 18.0 0.4 0.07 13.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.4 AAS50968.2 - 0.0032 16.9 0.0 2.9 7.3 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 AAS50968.2 - 0.021 14.3 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 AAS50968.2 - 0.027 14.1 4.5 0.053 13.2 0.7 3.0 2 1 0 2 2 2 0 Archaeal ATPase Miro PF08477.8 AAS50968.2 - 0.028 14.9 0.0 1.3 9.5 0.0 3.0 2 0 0 2 2 2 0 Miro-like protein FeoB_N PF02421.13 AAS50968.2 - 0.066 12.4 0.5 8.9 5.5 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Sec62 PF03839.11 AAS50969.2 - 1.9e-56 191.0 0.0 2.2e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 OAD_gamma PF04277.8 AAS50969.2 - 0.47 10.8 2.6 1.3 9.4 0.7 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Type_III_YscX PF09474.5 AAS50970.2 - 0.34 10.9 2.4 0.25 11.3 0.1 1.9 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) LigB PF02900.13 AAS50971.1 - 3.1e-33 114.9 0.0 4.4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF3767 PF12597.3 AAS50972.1 - 1.1e-42 144.4 0.2 1.5e-42 143.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF3353 PF11833.3 AAS50972.1 - 0.14 11.6 1.1 0.22 10.9 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) Sel1 PF08238.7 AAS50973.1 - 7.8e-28 96.2 20.3 4.2e-05 24.0 0.0 8.1 7 1 0 7 7 7 5 Sel1 repeat TPR_17 PF13431.1 AAS50973.1 - 0.023 14.8 1.2 8.4 6.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 AAS50973.1 - 0.19 12.2 6.7 3.7 8.2 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 AAS50973.1 - 1.1 9.0 8.3 21 4.8 0.3 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat CGI-121 PF08617.5 AAS50974.2 - 2e-32 112.0 0.0 2.5e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 MAT1 PF06391.8 AAS50975.1 - 1.4e-52 178.2 25.9 1.8e-52 177.8 18.0 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_3 PF13920.1 AAS50975.1 - 0.0022 17.6 4.9 0.0039 16.8 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS50975.1 - 0.003 17.5 6.0 0.0082 16.1 4.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AAS50975.1 - 0.0071 16.1 5.8 0.014 15.2 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AAS50975.1 - 0.0071 15.9 5.5 0.026 14.1 3.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-piccolo PF05715.8 AAS50975.1 - 0.097 12.6 1.1 0.19 11.7 0.8 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING_5 PF14634.1 AAS50975.1 - 0.099 12.3 9.1 0.79 9.5 6.2 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 AAS50975.1 - 0.33 10.7 4.0 0.96 9.2 2.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger 3HCDH_N PF02737.13 AAS50975.1 - 0.98 9.0 3.9 1.9 8.1 2.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-RING_4 PF14570.1 AAS50975.1 - 1.1 8.9 9.5 9.8 5.8 6.6 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-DHHC PF01529.15 AAS50976.2 - 3.3e-25 88.4 0.6 3.3e-25 88.4 0.4 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase A_deaminase PF00962.17 AAS50977.1 - 4.2e-116 387.4 0.0 5.8e-116 387.0 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase THP2 PF09432.5 AAS50978.2 - 6.3e-51 171.6 0.0 9.6e-51 171.0 0.0 1.3 1 0 0 1 1 1 1 Tho complex subunit THP2 L27 PF02828.11 AAS50978.2 - 0.061 13.0 0.4 0.26 10.9 0.2 2.3 2 0 0 2 2 2 0 L27 domain FdhE PF04216.7 AAS50978.2 - 1.4 8.5 5.3 5.2 6.7 0.7 2.3 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation APC8 PF04049.8 AAS50979.2 - 5.3e-40 136.4 0.0 9.5e-40 135.6 0.0 1.4 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 AAS50979.2 - 1.5e-26 90.8 22.4 3.3e-05 23.3 0.0 7.2 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 AAS50979.2 - 2.1e-25 88.1 19.0 8.5e-10 38.1 0.3 5.7 5 1 1 6 6 5 4 TPR repeat TPR_2 PF07719.12 AAS50979.2 - 2.7e-21 73.7 20.1 0.00018 21.1 0.0 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 AAS50979.2 - 1.6e-19 68.1 18.0 0.00083 18.9 0.0 7.7 6 1 2 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 AAS50979.2 - 1.4e-15 56.3 0.9 0.0081 16.7 0.0 6.2 4 1 3 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 AAS50979.2 - 3.9e-14 52.3 16.7 2.6e-05 24.0 0.1 5.8 2 1 3 5 5 5 5 Tetratricopeptide repeat Apc3 PF12895.2 AAS50979.2 - 1.1e-10 41.5 22.2 0.00019 21.5 2.5 5.2 4 1 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 AAS50979.2 - 7.7e-10 39.1 6.1 3.1e-05 24.5 0.0 5.8 5 1 2 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 AAS50979.2 - 6.5e-08 31.8 5.7 0.063 13.1 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat ChAPs PF09295.5 AAS50979.2 - 3.2e-07 29.4 0.3 8.4e-07 28.0 0.1 1.8 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_17 PF13431.1 AAS50979.2 - 5.7e-07 29.2 16.0 0.0064 16.6 0.1 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 AAS50979.2 - 6e-07 29.7 0.2 0.0055 17.0 0.2 4.3 4 1 1 5 5 3 1 Tetratricopeptide repeat BTAD PF03704.12 AAS50979.2 - 1.4e-05 25.4 1.2 0.00034 20.9 0.1 3.0 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_9 PF13371.1 AAS50979.2 - 2.2e-05 24.1 2.8 0.073 12.9 0.7 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 AAS50979.2 - 5e-05 22.4 2.3 0.0025 16.9 0.5 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 AAS50979.2 - 0.00012 22.2 15.8 3 8.5 0.0 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat HTH_Tnp_Mu_2 PF09039.6 AAS50979.2 - 0.011 15.4 0.2 0.027 14.1 0.2 1.6 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain Rep_N PF08724.5 AAS50979.2 - 0.031 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Rep protein catalytic domain like TPR_10 PF13374.1 AAS50979.2 - 0.048 13.6 0.0 2.8 7.9 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat Sel1 PF08238.7 AAS50979.2 - 0.53 10.9 10.6 43 4.9 0.0 5.3 5 0 0 5 5 5 0 Sel1 repeat PROCN PF08083.6 AAS50980.2 - 1.4e-221 735.1 11.3 2.6e-221 734.3 7.8 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 AAS50980.2 - 1e-123 411.0 1.5 1.9e-123 410.2 1.0 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 AAS50980.2 - 2.1e-87 290.4 0.5 4.2e-87 289.5 0.3 1.5 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 AAS50980.2 - 3e-78 260.6 2.7 6.4e-78 259.6 1.9 1.6 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 AAS50980.2 - 1.5e-65 218.8 0.0 3e-65 217.9 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 AAS50980.2 - 4.1e-47 158.9 0.0 1.2e-46 157.4 0.0 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 AAS50980.2 - 2e-44 149.3 0.1 6.6e-44 147.7 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 zf-C3H1 PF10650.4 AAS50981.1 - 0.0098 15.3 0.4 0.017 14.5 0.3 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain Chorismate_bind PF00425.13 AAS50982.1 - 5.1e-91 304.5 0.0 1.4e-90 303.1 0.0 1.7 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 AAS50982.1 - 1.7e-27 96.1 0.9 3.6e-25 88.5 0.0 3.3 3 1 0 3 3 3 1 Anthranilate synthase component I, N terminal region DUF466 PF04328.8 AAS50982.1 - 0.0086 15.8 0.1 0.72 9.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF466) PTH2 PF01981.11 AAS50983.1 - 6.9e-46 154.6 0.5 1.3e-45 153.8 0.2 1.5 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 PAS_4 PF08448.5 AAS50983.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold SEP PF08059.8 AAS50984.1 - 5.7e-25 87.4 0.2 1.2e-24 86.4 0.1 1.6 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 AAS50984.1 - 2.7e-11 42.7 0.1 5.9e-11 41.7 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 AAS50984.1 - 5.7e-11 42.3 0.0 9.5e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain Meth_synt_2 PF01717.13 AAS50985.2 - 6.5e-142 472.2 0.0 5.5e-136 452.7 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 AAS50985.2 - 2.1e-128 428.0 0.0 7e-117 390.1 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain RICTOR_N PF14664.1 AAS50987.2 - 5.2e-107 357.6 15.0 1.5e-106 356.1 10.2 1.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 AAS50987.2 - 8.9e-81 270.2 17.3 3.9e-80 268.0 0.9 5.4 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.1 AAS50987.2 - 7.5e-29 99.4 0.1 1.7e-26 91.9 0.0 3.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.1 AAS50987.2 - 3.6e-26 91.3 0.6 3.4e-25 88.2 0.1 2.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_2 PF13646.1 AAS50987.2 - 0.00014 22.0 0.2 5.4 7.3 0.0 4.7 4 0 0 4 4 4 1 HEAT repeats Seryl_tRNA_N PF02403.17 AAS50987.2 - 0.0019 18.1 5.0 0.01 15.8 3.5 2.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.3 AAS50987.2 - 0.002 17.8 9.9 0.064 12.9 6.8 2.6 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding HEAT PF02985.17 AAS50987.2 - 0.0034 17.3 0.3 3.6 7.9 0.0 4.4 4 0 0 4 4 3 1 HEAT repeat HR1 PF02185.11 AAS50987.2 - 0.0083 15.8 8.5 0.078 12.7 0.4 2.8 2 0 0 2 2 2 1 Hr1 repeat Vac14_Fab1_bd PF12755.2 AAS50987.2 - 0.026 14.9 0.1 0.73 10.2 0.1 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Laminin_II PF06009.7 AAS50987.2 - 0.036 13.8 5.5 3.2 7.5 4.3 3.1 2 1 0 2 2 2 0 Laminin Domain II Plasmid_stabil PF05016.9 AAS50987.2 - 0.046 14.1 0.4 0.66 10.3 0.0 3.1 2 0 0 2 2 2 0 Plasmid stabilisation system protein Mnd1 PF03962.10 AAS50987.2 - 0.07 12.7 6.6 0.18 11.4 4.6 1.6 1 0 0 1 1 1 0 Mnd1 family DUF3596 PF12167.3 AAS50987.2 - 0.086 12.3 2.0 0.18 11.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) CENP-F_leu_zip PF10473.4 AAS50987.2 - 0.096 12.5 8.2 0.24 11.2 5.7 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 AAS50987.2 - 0.17 11.4 8.1 1 8.8 0.8 2.8 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.6 AAS50987.2 - 0.21 11.2 8.0 5.6 6.6 0.4 2.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.2 AAS50987.2 - 0.23 11.3 9.9 0.62 9.9 6.9 1.6 1 0 0 1 1 1 0 Tropomyosin like TMF_DNA_bd PF12329.3 AAS50987.2 - 0.45 10.3 11.1 0.3 10.9 1.5 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.1 AAS50987.2 - 3 8.3 11.0 3.4 8.1 1.9 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Surfac_D-trimer PF09006.6 AAS50987.2 - 3.5 7.4 5.3 1.1 9.0 0.5 2.5 2 1 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Syntaxin PF00804.20 AAS50987.2 - 4.4 7.5 12.9 0.1 12.7 0.5 3.7 3 1 1 4 4 3 0 Syntaxin NPV_P10 PF05531.7 AAS50987.2 - 5 7.4 11.3 0.8 9.9 0.4 3.9 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.8 AAS50987.2 - 7.5 7.3 9.9 41 4.9 0.1 3.4 2 1 0 2 2 2 0 Occludin homology domain Cmc1 PF08583.5 AAS50989.1 - 8.4e-18 63.9 6.6 1.2e-17 63.4 4.6 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CBM_14 PF01607.19 AAS50989.1 - 0.034 14.0 0.6 0.046 13.6 0.4 1.2 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain DUF1922 PF09082.5 AAS50989.1 - 0.069 13.2 0.1 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) CHCH PF06747.8 AAS50989.1 - 0.14 12.1 3.4 6.4 6.8 0.1 2.5 2 0 0 2 2 2 0 CHCH domain Proteasome PF00227.21 AAS50990.2 - 2.1e-39 134.7 0.0 2.6e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sec7 PF01369.15 AAS50991.1 - 2.2e-26 92.6 0.1 4.9e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain Pkr1 PF08636.5 AAS50992.1 - 0.81 9.7 8.5 2.5 8.2 2.3 2.6 2 0 0 2 2 2 0 ER protein Pkr1 Ras PF00071.17 AAS50993.1 - 5e-63 211.3 0.4 5.9e-63 211.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS50993.1 - 9.1e-21 74.5 0.1 1.6e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS50993.1 - 1.7e-18 66.4 0.2 2.2e-18 66.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AAS50993.1 - 2.9e-07 29.8 0.1 3.9e-07 29.4 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AAS50993.1 - 3.2e-05 23.4 0.2 6.8e-05 22.3 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AAS50993.1 - 5.9e-05 23.0 0.1 8.7e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 AAS50993.1 - 0.0014 17.8 0.1 0.0022 17.2 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 AAS50993.1 - 0.0014 18.7 0.0 0.0028 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 AAS50993.1 - 0.0048 17.0 0.1 0.16 12.1 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 AAS50993.1 - 0.0095 15.2 0.2 0.053 12.7 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.13 AAS50993.1 - 0.0098 14.9 0.1 0.12 11.4 0.0 2.1 2 0 0 2 2 2 1 Septin AAA_16 PF13191.1 AAS50993.1 - 0.016 15.2 0.1 0.065 13.2 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 AAS50993.1 - 0.017 14.3 0.0 0.034 13.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 AAS50993.1 - 0.037 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 AAS50993.1 - 0.064 12.9 0.0 0.13 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 AAS50993.1 - 0.075 13.3 0.0 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter DUF788 PF05620.6 AAS50994.1 - 2e-25 89.5 0.0 2.2e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Actin PF00022.14 AAS50995.1 - 9.6e-161 534.5 0.0 1.1e-160 534.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 AAS50995.1 - 0.044 14.1 0.0 0.18 12.1 0.0 2.0 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Sugar_tr PF00083.19 AAS50996.2 - 1.2e-69 235.1 36.5 1.6e-69 234.6 25.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AAS50996.2 - 2e-18 66.2 31.8 1.1e-15 57.1 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AAS50996.2 - 0.0036 15.7 4.2 0.0036 15.7 2.9 3.7 2 2 1 4 4 4 2 MFS/sugar transport protein MscL PF01741.13 AAS50996.2 - 0.82 9.8 6.2 0.27 11.4 1.2 2.3 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL SPC22 PF04573.7 AAS50997.2 - 3.4e-63 212.0 0.2 4e-63 211.7 0.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit PPR_3 PF13812.1 AAS50998.1 - 7.4e-15 53.9 7.7 0.0064 16.6 0.0 9.8 11 0 0 11 11 11 3 Pentatricopeptide repeat domain PPR PF01535.15 AAS50998.1 - 6.1e-09 35.2 2.0 0.98 9.5 0.0 7.1 8 0 0 8 8 8 3 PPR repeat TPR_14 PF13428.1 AAS50998.1 - 1.2e-08 34.8 5.1 2.3 9.0 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat PPR_2 PF13041.1 AAS50998.1 - 3.2e-07 30.1 0.1 1.7 8.6 0.0 6.2 6 1 1 7 7 7 2 PPR repeat family ATP13 PF12921.2 AAS50998.1 - 0.011 15.0 0.4 8.8 5.7 0.0 4.1 4 1 0 4 4 4 0 Mitochondrial ATPase expression TPR_16 PF13432.1 AAS50998.1 - 0.28 11.9 4.5 21 5.9 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat rRNA_processing PF08524.6 AAS50999.1 - 2.1e-47 160.5 34.3 2.4e-47 160.4 23.7 1.0 1 0 0 1 1 1 1 rRNA processing hDGE_amylase PF14701.1 AAS50999.1 - 1.6 7.5 8.5 1.7 7.4 5.9 1.0 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Hom_end_hint PF05203.11 AAS50999.1 - 3.4 7.3 11.1 3.8 7.1 7.7 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint GAGA_bind PF06217.7 AAS50999.1 - 7.5 6.4 15.4 9.4 6.0 10.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family alpha-hel2 PF14456.1 AAS50999.1 - 8.2 5.0 7.0 10 4.8 4.8 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 GTP_EFTU PF00009.22 AAS51000.2 - 3.9e-60 202.5 0.4 8.2e-60 201.4 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 AAS51000.2 - 1.2e-33 115.1 0.1 3.2e-33 113.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 AAS51000.2 - 1.6e-31 107.9 0.0 3.9e-31 106.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 AAS51000.2 - 1.9e-22 78.8 0.0 3.9e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AAS51000.2 - 6.8e-14 51.7 0.3 1.6e-13 50.5 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 AAS51000.2 - 0.0069 16.8 0.2 0.027 14.9 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Cu-oxidase_2 PF07731.9 AAS51001.2 - 6.2e-42 142.3 7.9 8.9e-39 132.1 0.5 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 AAS51001.2 - 2.5e-40 136.8 3.8 6.1e-37 125.9 0.3 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 AAS51001.2 - 1.6e-33 115.8 1.8 1.1e-28 100.1 0.1 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 AAS51001.2 - 0.0084 15.9 0.0 7.4 6.5 0.0 4.0 4 1 0 4 4 4 1 Cupredoxin-like domain Antitoxin-MazE PF04014.13 AAS51001.2 - 0.2 11.4 0.0 25 4.7 0.0 2.5 2 0 0 2 2 2 0 Antidote-toxin recognition MazE ADH_N PF08240.7 AAS51002.1 - 7.7e-28 96.4 0.1 2.2e-27 94.9 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AAS51002.1 - 1.8e-24 85.7 0.1 3e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AAS51002.1 - 0.00073 20.4 0.0 0.0014 19.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 AAS51002.1 - 0.0029 17.2 0.4 0.0052 16.3 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 AAS51002.1 - 0.0034 16.7 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 AAS51002.1 - 0.028 14.4 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AAS51002.1 - 0.032 14.6 0.3 0.42 11.0 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 AAS51002.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 AAS51002.1 - 0.14 10.5 0.2 0.26 9.7 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Med14 PF08638.6 AAS51003.2 - 2.3e-64 216.2 2.6 3.8e-64 215.5 0.3 2.4 2 0 0 2 2 2 1 Mediator complex subunit MED14 GRAM PF02893.15 AAS51004.1 - 1.6e-17 62.7 0.0 3.2e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 GRAM domain USP8_dimer PF08969.6 AAS51005.2 - 0.00022 21.1 0.1 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain OTU PF02338.14 AAS51006.2 - 8.4e-13 48.9 0.0 1.3e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease BIR PF00653.16 AAS51006.2 - 0.081 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain zf-C2H2_jaz PF12171.3 AAS51007.1 - 5.7e-11 42.2 3.2 1e-10 41.4 2.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 AAS51007.1 - 0.00042 20.3 0.0 0.00062 19.8 0.0 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 AAS51007.1 - 0.0016 18.5 1.6 0.0027 17.8 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 AAS51007.1 - 0.0051 16.3 1.1 0.009 15.5 0.7 1.3 1 0 0 1 1 1 1 U1 zinc finger DUF802 PF05650.6 AAS51007.1 - 0.061 13.4 3.6 0.18 11.9 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF802) zf-C2H2_4 PF13894.1 AAS51007.1 - 0.064 13.6 1.2 0.14 12.5 0.9 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Apolipoprotein PF01442.13 AAS51007.1 - 0.082 12.4 1.4 0.11 12.0 0.9 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Ribosomal_L16 PF00252.13 AAS51008.1 - 1e-34 119.1 0.1 1.4e-34 118.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PMM PF03332.8 AAS51009.1 - 2.1e-109 364.2 0.4 2.5e-109 364.0 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 AAS51009.1 - 0.00028 20.5 0.0 0.0026 17.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 AAS51009.1 - 0.016 14.2 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAD PF12710.2 AAS51009.1 - 0.13 12.3 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AAS51009.1 - 0.17 12.2 0.1 0.24 11.7 0.1 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1640 PF07798.6 AAS51010.2 - 3.7e-63 212.7 7.4 4.3e-63 212.5 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) YfbU PF03887.9 AAS51010.2 - 0.045 13.3 0.7 1.1 8.8 0.1 2.1 1 1 1 2 2 2 0 YfbU domain Chalcone PF02431.10 AAS51010.2 - 0.049 13.0 0.8 0.062 12.6 0.6 1.3 1 0 0 1 1 1 0 Chalcone-flavanone isomerase DUF1732 PF08340.6 AAS51010.2 - 0.052 13.3 8.6 0.058 13.2 5.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1732) V-ATPase_G PF03179.10 AAS51010.2 - 0.057 13.7 1.7 0.11 12.7 1.2 1.5 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit FlaC_arch PF05377.6 AAS51010.2 - 0.062 13.2 3.3 2 8.3 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YjfB_motility PF14070.1 AAS51010.2 - 0.12 12.1 2.0 8 6.3 0.7 2.4 2 0 0 2 2 2 0 Putative motility protein PLRV_ORF5 PF01690.12 AAS51010.2 - 0.17 10.9 0.6 0.29 10.2 0.0 1.6 1 1 0 1 1 1 0 Potato leaf roll virus readthrough protein ApoLp-III PF07464.6 AAS51010.2 - 0.19 11.7 4.8 0.37 10.8 2.5 2.0 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Phage_Mu_Gam PF07352.7 AAS51010.2 - 0.29 10.6 7.6 0.39 10.2 0.3 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein COG5 PF10392.4 AAS51010.2 - 0.6 10.0 6.4 9 6.2 3.8 2.5 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Phage_lysis PF03245.8 AAS51010.2 - 0.76 9.7 10.7 0.66 9.9 0.3 2.3 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein TBPIP PF07106.8 AAS51010.2 - 0.94 9.0 9.3 1.9 7.9 6.4 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_PEP_C PF04513.7 AAS51010.2 - 1.7 8.4 7.1 2.1 8.1 2.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4446 PF14584.1 AAS51010.2 - 2.7 7.7 7.3 0.68 9.7 1.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) FliD_C PF07195.7 AAS51010.2 - 3.9 6.7 9.7 3 7.0 0.9 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus RCC1 PF00415.13 AAS51011.2 - 3e-28 97.7 5.5 1.7e-06 28.1 0.0 6.5 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AAS51011.2 - 3.6e-19 67.8 10.9 1.1e-10 40.8 0.0 4.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat V-SNARE_C PF12352.3 AAS51012.2 - 2.4e-09 37.1 4.8 4.6e-09 36.2 3.3 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 AAS51012.2 - 3.9e-07 29.6 0.1 6.7e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Sec20 PBC PF03792.8 AAS51013.1 - 0.03 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 PBC domain FCH PF00611.18 AAS51014.1 - 6.1e-12 45.5 0.0 6.1e-12 45.5 0.0 3.4 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 AAS51014.1 - 1e-10 41.4 0.0 4.3e-10 39.3 0.0 2.1 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.16 AAS51014.1 - 3.2e-08 33.1 0.0 7.2e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Rdx PF10262.4 AAS51015.2 - 1.4e-26 92.3 0.0 1.9e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Rdx family Lectin_leg-like PF03388.8 AAS51016.1 - 2.2e-38 131.6 0.0 3.4e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 AAS51016.1 - 0.0012 18.2 0.0 0.024 14.0 0.0 2.1 2 0 0 2 2 2 1 Legume lectin domain Toxin_52 PF15605.1 AAS51016.1 - 0.0051 16.6 0.5 0.012 15.5 0.4 1.7 1 1 0 1 1 1 1 Putative toxin 52 DUF536 PF04394.9 AAS51016.1 - 8.3 6.2 19.8 1.2 8.9 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF536 CRC_subunit PF08624.5 AAS51017.1 - 5.5e-42 142.9 0.0 9e-42 142.2 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit SidE PF12252.3 AAS51017.1 - 0.043 11.1 0.0 0.06 10.6 0.0 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein Mannosyl_trans3 PF11051.3 AAS51018.2 - 1e-65 221.7 0.0 1.4e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative adh_short PF00106.20 AAS51019.2 - 6.9e-31 107.4 1.8 7.8e-31 107.2 0.6 1.6 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 AAS51019.2 - 5.6e-16 58.7 1.3 8.5e-16 58.1 0.9 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AAS51019.2 - 3.2e-14 53.3 0.5 4.1e-14 52.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AAS51019.2 - 9.6e-07 28.4 0.5 6.2e-06 25.8 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AAS51019.2 - 2.4e-05 24.4 1.5 3.8e-05 23.7 1.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AAS51019.2 - 0.0032 16.2 0.2 0.0044 15.7 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.5 AAS51019.2 - 0.013 14.6 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TrkA_N PF02254.13 AAS51019.2 - 0.016 15.2 0.3 0.037 14.0 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_18 PF12847.2 AAS51019.2 - 0.092 13.3 0.0 0.34 11.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 AAS51019.2 - 0.1 11.4 0.1 0.28 10.0 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein HAD PF12710.2 AAS51019.2 - 0.27 11.3 1.1 4.3 7.4 0.8 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase adh_short PF00106.20 AAS51020.1 - 9.5e-32 110.2 2.0 9.5e-32 110.2 1.4 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AAS51020.1 - 2.1e-16 60.1 0.9 2.1e-16 60.1 0.6 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 AAS51020.1 - 6.3e-16 58.8 0.3 7.7e-16 58.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AAS51020.1 - 4.5e-05 22.9 0.8 0.0001 21.8 0.6 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AAS51020.1 - 0.00014 21.9 1.4 0.00019 21.4 0.9 1.4 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 AAS51020.1 - 0.0038 16.1 0.1 0.0046 15.8 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 AAS51020.1 - 0.0084 16.1 2.0 0.02 14.8 0.4 2.4 2 1 0 3 3 3 1 TrkA-N domain DUF1776 PF08643.5 AAS51020.1 - 0.01 15.0 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.14 AAS51020.1 - 0.014 14.0 0.4 0.019 13.6 0.3 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 AAS51020.1 - 0.053 13.3 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Enoyl_reductase PF12241.3 AAS51020.1 - 0.095 11.6 0.2 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region HAD PF12710.2 AAS51020.1 - 0.2 11.7 0.4 2 8.5 0.3 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase adh_short PF00106.20 AAS51021.1 - 2e-33 115.6 1.3 2e-33 115.6 0.9 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AAS51021.1 - 3.6e-16 59.3 0.9 6.3e-16 58.5 0.6 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AAS51021.1 - 1.1e-14 54.8 0.2 1.3e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AAS51021.1 - 4.5e-06 26.2 0.5 7.1e-06 25.6 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AAS51021.1 - 0.00033 20.7 2.5 0.00037 20.5 0.8 1.6 1 1 0 2 2 2 1 NADH(P)-binding TrkA_N PF02254.13 AAS51021.1 - 0.0048 16.8 2.1 0.01 15.8 0.2 2.3 2 1 1 3 3 3 1 TrkA-N domain Polysacc_synt_2 PF02719.10 AAS51021.1 - 0.0064 15.4 0.1 0.0099 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 AAS51021.1 - 0.014 14.1 0.4 0.019 13.7 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family LexA_DNA_bind PF01726.11 AAS51021.1 - 0.048 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain Eno-Rase_NADH_b PF12242.3 AAS51021.1 - 0.086 12.6 0.4 0.42 10.4 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 AAS51021.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.20 AAS51022.1 - 3.1e-32 111.7 2.1 5.6e-32 110.9 1.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AAS51022.1 - 2.8e-16 59.6 1.2 4.9e-16 58.9 0.8 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AAS51022.1 - 7.4e-16 58.6 0.5 9.2e-16 58.3 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AAS51022.1 - 4.5e-06 26.2 0.6 9.8e-06 25.1 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AAS51022.1 - 0.00024 21.1 1.8 0.00038 20.5 0.8 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 AAS51022.1 - 0.0043 15.9 0.2 0.0084 15.0 0.1 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 AAS51022.1 - 0.0052 15.5 0.5 0.0069 15.1 0.4 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 AAS51022.1 - 0.0054 16.7 0.3 0.012 15.6 0.2 1.6 1 0 0 1 1 1 1 TrkA-N domain OPT PF03169.10 AAS51023.2 - 5e-153 510.8 40.5 5.8e-153 510.6 28.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 AAS51023.2 - 0.24 10.4 0.3 0.7 8.9 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) MFS_1 PF07690.11 AAS51025.1 - 2.1e-20 72.7 21.7 2.7e-18 65.8 4.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_76 PF03663.9 AAS51026.1 - 2.7e-138 461.3 5.8 3.5e-138 461.0 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.9 AAS51027.1 - 3.7e-144 480.6 1.9 4.6e-144 480.3 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.9 AAS51028.1 - 4.1e-144 480.5 1.6 5.1e-144 480.2 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Peptidase_M16 PF00675.15 AAS51029.2 - 2.3e-27 95.5 0.0 3.7e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AAS51029.2 - 5.9e-11 42.3 0.1 3.1e-10 40.0 0.0 2.0 2 1 0 2 2 2 1 Peptidase M16 inactive domain IlvC PF01450.14 AAS51030.2 - 7.4e-47 158.9 0.0 1.2e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 AAS51030.2 - 5.2e-44 149.5 0.0 7.5e-44 149.0 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 AAS51030.2 - 0.011 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AhpC-TSA PF00578.16 AAS51031.1 - 7.9e-31 106.3 0.0 1.2e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 AAS51031.1 - 1.4e-08 34.1 0.1 2.1e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 AAS51031.1 - 5.4e-08 32.4 0.0 7.2e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin Transaldolase PF00923.14 AAS51032.2 - 6.1e-97 324.1 0.0 7e-97 324.0 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Zn_clus PF00172.13 AAS51033.1 - 1.8e-08 34.1 10.1 1.8e-08 34.1 7.0 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2439 PF10382.4 AAS51034.2 - 2.4e-26 91.7 0.1 3.1e-26 91.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) TMEM171 PF15471.1 AAS51035.1 - 0.54 9.0 2.6 1.2 7.8 1.8 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 LRR_4 PF12799.2 AAS51036.1 - 1e-05 24.9 5.2 0.001 18.6 0.3 4.3 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 AAS51036.1 - 0.0041 17.0 4.8 27 5.5 0.1 5.3 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 AAS51036.1 - 0.0048 16.7 3.1 28 5.2 0.0 5.3 4 1 0 4 4 4 0 Leucine Rich Repeat F-box-like PF12937.2 AAS51036.1 - 0.022 14.4 0.0 0.062 13.0 0.0 1.8 1 0 0 1 1 1 0 F-box-like Spatacsin_C PF14649.1 AAS51036.1 - 0.048 12.5 0.2 0.08 11.7 0.2 1.2 1 0 0 1 1 1 0 Spatacsin C-terminus LRR_8 PF13855.1 AAS51036.1 - 0.59 9.9 7.5 0.16 11.7 1.3 3.2 4 0 0 4 4 4 0 Leucine rich repeat Pkinase PF00069.20 AAS51037.1 - 2.8e-72 243.0 0.0 3.7e-72 242.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51037.1 - 1.3e-32 112.8 0.0 1.9e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS51037.1 - 6.1e-06 25.4 0.0 1e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 AAS51037.1 - 0.00017 20.7 0.0 0.00028 20.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AAS51037.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3388 PF11868.3 AAS51037.1 - 0.092 11.8 0.1 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) CN_hydrolase PF00795.17 AAS51038.1 - 6.6e-32 110.3 0.0 9.1e-32 109.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PA PF02225.17 AAS51038.1 - 0.3 10.7 1.2 4.3 7.0 0.0 2.5 2 1 0 2 2 2 0 PA domain ORMDL PF04061.9 AAS51039.1 - 9.6e-58 193.5 6.4 1.1e-57 193.3 4.4 1.1 1 0 0 1 1 1 1 ORMDL family ACBP PF00887.14 AAS51040.1 - 1.9e-28 97.9 1.4 2.1e-28 97.7 1.0 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 AAS51040.1 - 0.018 15.2 0.1 2.6 8.2 0.0 2.0 1 1 0 2 2 2 0 FERM central domain HEAT PF02985.17 AAS51041.2 - 2.2e-19 67.7 17.1 9.7e-05 22.1 0.0 11.5 12 0 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.1 AAS51041.2 - 6.1e-12 45.6 14.0 3.5e-06 27.3 0.0 9.2 9 1 2 11 11 11 1 HEAT-like repeat IBN_N PF03810.14 AAS51041.2 - 7e-11 41.8 0.2 1.1e-09 38.0 0.2 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 AAS51041.2 - 1.7e-10 41.0 14.3 0.0001 22.4 0.0 7.6 3 1 4 8 8 8 3 HEAT repeats Arm PF00514.18 AAS51041.2 - 8.5e-06 25.4 10.4 0.0095 15.7 0.1 6.2 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 AAS51041.2 - 1e-05 25.0 1.6 0.16 11.2 0.0 4.6 4 1 0 5 5 5 2 CLASP N terminal Cnd3 PF12719.2 AAS51041.2 - 0.00031 19.8 6.0 0.007 15.3 0.5 4.0 2 2 2 4 4 4 1 Nuclear condensing complex subunits, C-term domain DUF3385 PF11865.3 AAS51041.2 - 0.0062 16.4 1.0 7.1 6.5 0.1 4.7 3 2 2 5 5 5 1 Domain of unknown function (DUF3385) PAP2 PF01569.16 AAS51042.1 - 2.8e-17 62.5 2.5 4.9e-17 61.8 1.6 1.5 1 1 0 1 1 1 1 PAP2 superfamily PrgI PF12666.2 AAS51042.1 - 1.3 9.1 4.7 0.98 9.6 0.3 2.3 2 1 0 2 2 2 0 PrgI family protein 6PF2K PF01591.13 AAS51043.1 - 4.9e-56 189.2 0.0 7.5e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 AAS51043.1 - 6.5e-18 65.3 0.7 2.4e-17 63.4 0.0 2.3 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 AAS51043.1 - 0.00022 21.1 0.1 0.00022 21.1 0.1 2.7 3 1 0 3 3 3 1 AAA domain KOW PF00467.24 AAS51044.1 - 5.3e-05 22.7 1.8 5.3e-05 22.7 1.2 2.1 2 0 0 2 2 2 1 KOW motif TIM21 PF08294.6 AAS51045.1 - 9.4e-58 193.9 0.0 1.1e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 TIM21 Glyco_hydro_72 PF03198.9 AAS51046.1 - 1.4e-138 461.2 0.2 1.8e-138 460.8 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 AAS51046.1 - 9.4e-14 51.6 0.4 2.4e-13 50.3 0.3 1.7 1 0 0 1 1 1 1 X8 domain Glucan_synthase PF02364.10 AAS51047.2 - 0 1426.9 0.0 0 1426.5 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 AAS51047.2 - 1.6e-38 131.2 0.1 3.5e-38 130.1 0.0 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Abhydrolase_6 PF12697.2 AAS51048.2 - 1.8e-33 116.3 7.0 2.2e-33 116.0 4.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AAS51048.2 - 1.2e-14 54.2 0.0 2e-14 53.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AAS51048.2 - 1.5e-14 54.1 0.0 2.3e-14 53.5 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 AAS51048.2 - 8.3e-09 36.0 0.1 1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 AAS51048.2 - 3.2e-05 23.6 0.0 4.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 AAS51048.2 - 0.00013 21.7 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 AAS51048.2 - 0.00037 20.1 0.1 0.00047 19.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 AAS51048.2 - 0.0062 15.9 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ribosomal_L10 PF00466.15 AAS51050.2 - 2.2e-28 98.1 0.3 4.1e-28 97.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 AAS51050.2 - 3.9e-16 59.2 5.0 7.4e-16 58.3 1.1 2.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein Alba PF01918.16 AAS51051.1 - 0.0062 16.1 0.1 0.0089 15.6 0.1 1.2 1 0 0 1 1 1 1 Alba Sec1 PF00995.18 AAS51051.1 - 0.045 12.3 0.3 0.049 12.2 0.2 1.0 1 0 0 1 1 1 0 Sec1 family ATP-synt PF00231.14 AAS51052.2 - 4.2e-67 226.5 4.9 4.8e-67 226.3 3.4 1.0 1 0 0 1 1 1 1 ATP synthase Fig1 PF12351.3 AAS51053.2 - 5.3e-54 182.8 0.8 5.3e-54 182.8 0.6 1.5 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 AAS51053.2 - 0.0059 16.1 15.3 0.03 13.8 10.6 1.9 1 1 0 1 1 1 1 SUR7/PalI family CcmH PF03918.9 AAS51053.2 - 0.96 8.4 3.1 2.9 6.8 0.0 2.7 3 0 0 3 3 3 0 Cytochrome C biogenesis protein DUF4131 PF13567.1 AAS51053.2 - 3.8 6.9 17.0 3.7 6.9 0.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) AMP-binding PF00501.23 AAS51054.2 - 3.1e-68 230.0 0.0 3.7e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AAS51054.2 - 0.00013 22.8 0.0 0.00027 21.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyltransferase PF01553.16 AAS51055.1 - 1.1e-28 99.2 0.0 1.7e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase MFS_1 PF07690.11 AAS51056.1 - 5.3e-38 130.6 25.4 5.3e-38 130.6 17.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1602 PF07673.9 AAS51058.2 - 0.029 13.8 1.4 0.1 12.0 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1602) YCII PF03795.9 AAS51059.1 - 1.7e-09 37.7 0.0 2e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Profilin PF00235.14 AAS51060.1 - 7.8e-40 135.7 0.1 8.7e-40 135.6 0.1 1.0 1 0 0 1 1 1 1 Profilin Leo1 PF04004.8 AAS51061.2 - 1.7e-44 151.5 0.1 3.2e-44 150.6 0.1 1.5 1 0 0 1 1 1 1 Leo1-like protein SIR2_2 PF13289.1 AAS51061.2 - 0.037 13.9 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 SIR2-like domain HUN PF08729.5 AAS51061.2 - 0.058 13.2 10.1 0.25 11.2 7.0 2.1 1 0 0 1 1 1 0 HPC2 and ubinuclein domain Glyco_hydro_18 PF00704.23 AAS51062.1 - 1.8e-75 254.5 1.7 2.2e-75 254.2 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GPP34 PF05719.6 AAS51063.1 - 5.7e-62 209.4 0.1 7.6e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) UCH PF00443.24 AAS51064.2 - 1.2e-56 191.7 0.0 7.7e-56 189.1 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 AAS51064.2 - 2.4e-43 145.3 6.6 1.9e-17 62.4 0.0 4.7 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 AAS51064.2 - 1.5e-07 31.2 0.1 0.00014 21.4 0.3 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DnaJ PF00226.26 AAS51064.2 - 0.0044 16.7 0.2 0.22 11.3 0.0 2.9 2 0 0 2 2 2 1 DnaJ domain EF-hand_1 PF00036.27 AAS51065.1 - 1.7e-29 98.8 2.8 6.3e-08 31.3 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 AAS51065.1 - 1.4e-25 86.7 1.4 1.8e-06 27.3 0.1 4.8 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 AAS51065.1 - 5.8e-24 84.0 2.7 5.4e-15 55.2 0.1 3.2 1 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 AAS51065.1 - 3.1e-20 70.5 2.9 1.1e-05 24.5 0.2 4.9 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 AAS51065.1 - 5.1e-19 67.6 4.0 3.3e-08 33.0 0.1 4.0 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 AAS51065.1 - 3.6e-07 30.2 0.4 0.034 14.1 0.1 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 AAS51065.1 - 4.5e-05 23.1 3.6 0.53 10.0 0.0 3.7 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 AAS51065.1 - 0.00053 19.8 0.1 0.02 14.7 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain S10_plectin PF03501.10 AAS51065.1 - 0.0052 16.6 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Plectin/S10 domain EF-hand_10 PF14788.1 AAS51065.1 - 0.017 14.7 0.4 6.9 6.4 0.0 3.4 3 0 0 3 3 3 0 EF hand COQ7 PF03232.8 AAS51066.1 - 4e-76 254.2 0.0 4.8e-76 254.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 DUF4611 PF15387.1 AAS51066.1 - 0.069 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) YTH PF04146.10 AAS51067.1 - 3.8e-38 130.2 0.1 5.8e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain Sel1 PF08238.7 AAS51068.1 - 1.8e-15 57.0 19.8 2e-05 25.0 0.2 8.6 8 0 0 8 8 8 4 Sel1 repeat TPR_7 PF13176.1 AAS51068.1 - 0.19 11.6 6.2 7.6 6.5 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Dynactin_p62 PF05502.8 AAS51069.1 - 8e-24 84.2 24.4 9.3e-12 44.4 0.1 2.1 1 1 0 2 2 2 2 Dynactin p62 family zf-Mss51 PF13824.1 AAS51069.1 - 0.19 11.5 10.4 0.14 12.0 3.5 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 CENP-X PF09415.5 AAS51070.1 - 7e-29 99.4 0.2 8.2e-29 99.2 0.1 1.1 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.18 AAS51070.1 - 0.071 13.1 0.1 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MTBP_mid PF14919.1 AAS51070.1 - 0.1 11.2 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 MDM2-binding ENTH PF01417.15 AAS51071.1 - 5.6e-40 136.0 0.0 1.1e-39 135.1 0.0 1.5 1 0 0 1 1 1 1 ENTH domain DNA_ligase_A_M PF01068.16 AAS51073.1 - 1.9e-58 197.1 0.1 2.7e-58 196.6 0.1 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 AAS51073.1 - 8.7e-56 188.5 0.0 1.4e-55 187.8 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 AAS51073.1 - 3.9e-23 81.6 0.0 1.1e-22 80.2 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Pox_C7_F8A PF03287.9 AAS51073.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus C7/F8A protein DNA_ligase_OB_2 PF14743.1 AAS51073.1 - 0.2 11.3 0.9 19 5.0 0.1 2.5 2 0 0 2 2 2 0 DNA ligase OB-like domain Heme_oxygenase PF01126.15 AAS51074.1 - 1e-16 61.1 1.4 2.7e-16 59.7 0.6 2.0 2 1 0 2 2 2 1 Heme oxygenase DUF1713 PF08213.6 AAS51075.1 - 2.1e-15 56.0 17.3 2.9e-15 55.5 12.0 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) zf-Mss51 PF13824.1 AAS51076.1 - 3.9e-20 71.4 0.6 8.2e-20 70.4 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 NOT2_3_5 PF04153.13 AAS51077.1 - 2.7e-34 117.9 0.1 3.5e-34 117.5 0.1 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family AAA_18 PF13238.1 AAS51078.1 - 2.1e-27 95.9 0.2 5.4e-27 94.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AAS51078.1 - 5.2e-16 59.5 0.2 1.5e-15 58.1 0.1 1.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 AAS51078.1 - 2.6e-05 24.1 0.0 0.0063 16.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AAS51078.1 - 7.7e-05 22.7 0.0 0.00034 20.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AAS51078.1 - 0.0002 21.4 0.5 0.0019 18.1 0.4 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 AAS51078.1 - 0.0011 19.1 0.0 0.004 17.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 AAS51078.1 - 0.0011 19.1 0.0 0.0027 17.8 0.0 1.6 2 0 0 2 2 2 1 RNA helicase ADK PF00406.17 AAS51078.1 - 0.0017 18.2 0.0 0.32 10.8 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase Zeta_toxin PF06414.7 AAS51078.1 - 0.0027 16.8 0.0 0.008 15.2 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 AAS51078.1 - 0.0034 17.2 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 AAS51078.1 - 0.0061 15.9 0.0 2.4 7.5 0.0 2.4 2 1 0 2 2 2 1 Thymidylate kinase T2SE PF00437.15 AAS51078.1 - 0.0068 15.3 0.0 0.017 14.0 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 AAS51078.1 - 0.0095 16.0 0.0 0.021 14.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 AAS51078.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.1 AAS51078.1 - 0.026 14.4 0.1 0.4 10.5 0.0 2.3 1 1 1 2 2 2 0 Cytidylate kinase-like family AAA_10 PF12846.2 AAS51078.1 - 0.032 13.6 0.1 0.093 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain KTI12 PF08433.5 AAS51078.1 - 0.032 13.4 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.16 AAS51078.1 - 0.035 13.2 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 AAS51078.1 - 0.04 12.5 0.0 0.055 12.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Imm47 PF15586.1 AAS51078.1 - 0.053 13.3 0.2 0.099 12.4 0.2 1.4 1 0 0 1 1 1 0 Immunity protein 47 AAA_19 PF13245.1 AAS51078.1 - 0.085 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain ATP_bind_1 PF03029.12 AAS51078.1 - 0.091 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 AAS51078.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cyt-b5 PF00173.23 AAS51078.1 - 0.11 12.3 0.2 0.31 10.8 0.0 1.8 2 0 0 2 2 1 0 Cytochrome b5-like Heme/Steroid binding domain ABC_tran PF00005.22 AAS51078.1 - 0.12 12.7 0.0 0.57 10.4 0.0 1.9 2 0 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.13 AAS51078.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family zf-RanBP PF00641.13 AAS51079.1 - 1.5e-19 68.7 12.3 5.9e-10 38.0 1.3 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 AAS51079.1 - 8.3e-09 34.9 0.0 0.00055 19.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS51079.1 - 0.00015 21.6 0.0 0.0022 17.9 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Med15 PF09606.5 AAS51079.1 - 0.012 13.8 33.1 0.016 13.4 22.9 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DZR PF12773.2 AAS51079.1 - 0.064 13.0 8.9 0.97 9.3 0.5 2.6 2 0 0 2 2 2 0 Double zinc ribbon PAT1 PF09770.4 AAS51079.1 - 2 6.5 29.9 2.8 6.0 20.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-ribbon_3 PF13248.1 AAS51079.1 - 6.4 6.1 8.8 15 4.9 0.4 2.7 2 1 0 2 2 2 0 zinc-ribbon domain ADH_N PF08240.7 AAS51080.1 - 6.4e-26 90.2 3.5 6.4e-26 90.2 2.4 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AAS51080.1 - 1.9e-22 79.2 0.3 3.2e-22 78.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 AAS51080.1 - 0.006 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 AAS51080.1 - 0.041 13.2 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 AAS51080.1 - 0.051 12.7 0.1 0.09 11.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HycI PF01750.13 AAS51080.1 - 0.11 11.9 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase maturation protease ELFV_dehydrog PF00208.16 AAS51080.1 - 0.11 11.9 1.6 0.23 11.0 1.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase COQ9 PF08511.6 AAS51081.1 - 1.6e-19 69.1 0.1 4.1e-19 67.8 0.0 1.7 2 0 0 2 2 2 1 COQ9 Prefoldin_2 PF01920.15 AAS51082.1 - 5.4e-24 83.9 11.1 5.8e-24 83.8 7.7 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF1192 PF06698.6 AAS51082.1 - 0.0029 17.3 4.7 0.0033 17.1 0.6 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1192) DUF2688 PF10892.3 AAS51082.1 - 0.066 12.8 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) Prefoldin PF02996.12 AAS51082.1 - 0.1 12.2 7.8 0.58 9.8 0.3 2.2 1 1 2 3 3 3 0 Prefoldin subunit CENP-F_leu_zip PF10473.4 AAS51082.1 - 0.12 12.2 10.4 0.76 9.6 1.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1732 PF08340.6 AAS51082.1 - 0.13 12.1 1.9 0.23 11.3 1.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) DASH_Dad3 PF08656.5 AAS51082.1 - 0.19 11.4 2.6 0.28 10.9 0.8 1.8 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4164 PF13747.1 AAS51082.1 - 0.25 11.5 5.7 0.56 10.3 0.8 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) YgaB PF14182.1 AAS51082.1 - 0.25 11.5 7.9 0.55 10.4 0.3 2.2 2 0 0 2 2 2 0 YgaB-like protein DUF4200 PF13863.1 AAS51082.1 - 0.36 10.7 12.0 1.3 9.0 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc24 PF08286.6 AAS51082.1 - 0.59 9.8 8.5 0.54 9.9 2.2 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 BLOC1_2 PF10046.4 AAS51082.1 - 0.67 10.1 4.2 0.59 10.3 0.7 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.2 AAS51082.1 - 1.8 8.4 12.1 9.2 6.1 8.4 1.9 1 1 0 1 1 1 0 Tropomyosin like DMPK_coil PF08826.5 AAS51082.1 - 2.2 8.2 12.8 1.1 9.1 1.9 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like Snf7 PF03357.16 AAS51082.1 - 2.5 7.4 9.1 0.25 10.6 0.5 2.1 2 0 0 2 2 2 0 Snf7 DUF1843 PF08898.5 AAS51082.1 - 2.5 8.2 7.5 3.2 7.8 1.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) FTA4 PF13093.1 AAS51082.1 - 4.7 6.5 8.9 6.1 6.2 6.2 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DivIVA PF05103.8 AAS51082.1 - 6.6 6.7 10.2 1.6 8.7 2.2 2.0 2 0 0 2 2 2 0 DivIVA protein Sugarporin_N PF11471.3 AAS51082.1 - 6.8 6.4 10.3 16 5.2 2.7 2.4 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Syntaxin PF00804.20 AAS51082.1 - 9.1 6.5 8.0 69 3.6 5.6 2.0 1 1 0 1 1 1 0 Syntaxin Atg14 PF10186.4 AAS51082.1 - 9.4 5.0 8.9 46 2.8 6.2 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tektin PF03148.9 AAS51082.1 - 9.7 4.6 9.5 7.5 4.9 1.8 2.0 2 0 0 2 2 2 0 Tektin family POC1 PF10450.4 AAS51083.2 - 1.2e-37 129.1 0.0 1.5e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 POC1 chaperone NTP_transf_3 PF12804.2 AAS51083.2 - 0.14 12.2 0.9 0.55 10.2 0.6 2.0 1 1 0 1 1 1 0 MobA-like NTP transferase domain Nop PF01798.13 AAS51084.1 - 2.2e-60 202.2 0.1 2.2e-60 202.2 0.0 2.0 2 1 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 AAS51084.1 - 6.9e-27 93.0 0.1 1.8e-26 91.6 0.1 1.8 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 AAS51084.1 - 4.7e-24 84.3 0.2 4.7e-24 84.3 0.1 3.4 2 1 1 3 3 3 1 NOP5NT (NUC127) domain SprA-related PF12118.3 AAS51084.1 - 0.002 17.5 28.1 0.0028 17.0 19.4 1.3 1 0 0 1 1 1 1 SprA-related family MIP-T3 PF10243.4 AAS51084.1 - 0.07 11.5 67.1 0.095 11.1 46.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 AAS51084.1 - 0.12 11.6 57.7 0.15 11.2 40.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.9 AAS51084.1 - 4.3 5.2 33.9 5.8 4.8 23.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Ion_trans PF00520.26 AAS51085.1 - 1.7e-83 278.8 98.6 1.6e-32 112.4 8.6 5.7 5 1 0 5 5 5 4 Ion transport protein EF-hand_1 PF00036.27 AAS51085.1 - 0.064 12.5 0.1 0.22 10.8 0.1 2.0 1 0 0 1 1 1 0 EF hand Gpi1 PF05024.10 AAS51086.1 - 4.5e-51 173.2 11.7 8.2e-51 172.3 8.1 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) MRP-S33 PF08293.6 AAS51087.1 - 8.4e-31 105.8 0.6 1e-30 105.5 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF4023 PF13215.1 AAS51087.1 - 0.071 12.9 0.2 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) Ribosomal_S2 PF00318.15 AAS51088.1 - 3.4e-40 137.5 0.1 1.7e-20 73.1 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 Ferric_reduct PF01794.14 AAS51089.1 - 4.8e-19 68.6 12.5 4.8e-19 68.6 8.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 AAS51089.1 - 0.0042 17.0 0.0 0.018 14.9 0.0 2.0 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 AAS51089.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain AATase PF07247.7 AAS51090.1 - 5.1e-54 183.6 0.0 6.5e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 AAS51090.1 - 4.6e-09 35.5 0.0 2.5e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Condensation domain zf-ZPR1 PF03367.8 AAS51091.1 - 1.4e-116 385.1 1.1 3.9e-60 201.6 0.2 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain APH PF01636.18 AAS51091.1 - 0.025 14.3 0.3 0.046 13.4 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family HypA PF01155.14 AAS51091.1 - 0.039 13.6 2.4 5.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family UPF0547 PF10571.4 AAS51091.1 - 0.059 13.0 7.9 0.62 9.8 0.2 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Cytochrom_C_2 PF01322.15 AAS51091.1 - 0.17 12.4 5.1 2 8.9 0.1 3.4 4 0 0 4 4 4 0 Cytochrome C' Lar_restr_allev PF14354.1 AAS51091.1 - 0.4 11.0 5.4 14 6.0 1.6 3.2 3 0 0 3 3 3 0 Restriction alleviation protein Lar Elf1 PF05129.8 AAS51091.1 - 0.55 9.9 3.1 12 5.6 0.0 2.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 AAS51091.1 - 0.7 9.6 6.6 18 5.1 0.1 3.9 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AAS51091.1 - 0.82 9.3 6.3 21 4.8 0.1 3.8 3 1 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 AAS51091.1 - 1.2 9.1 6.4 7.4 6.6 0.0 3.8 4 0 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 AAS51091.1 - 5 6.7 14.6 1.5 8.3 0.6 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 AAS51091.1 - 8.9 6.2 8.2 9.9 6.0 0.0 3.4 4 0 0 4 4 4 0 Transposase zinc-ribbon domain MMR_HSR1_C PF08438.5 AAS51092.2 - 2.6e-30 104.8 0.0 4e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 AAS51092.2 - 4.3e-18 65.3 0.0 8.6e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AAS51092.2 - 4.7e-07 29.1 0.0 1.6e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 AAS51092.2 - 0.0013 18.1 0.1 1.9 7.9 0.0 2.9 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AAS51092.2 - 0.032 14.0 0.2 0.093 12.5 0.1 1.8 2 0 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.12 AAS51092.2 - 0.046 13.2 0.1 15 4.9 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 AAS51092.2 - 0.077 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AA_permease PF00324.16 AAS51093.1 - 2.1e-116 389.1 36.1 2.5e-116 388.8 25.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS51093.1 - 6.9e-31 107.2 38.0 9.7e-31 106.7 26.3 1.2 1 0 0 1 1 1 1 Amino acid permease TPP_enzyme_M PF00205.17 AAS51094.1 - 2.6e-34 117.9 0.0 9.3e-34 116.1 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 AAS51094.1 - 2e-33 115.3 0.0 3.1e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AAS51094.1 - 1.4e-14 53.9 0.0 2.3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 AAS51094.1 - 0.082 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit RRM_6 PF14259.1 AAS51095.1 - 8.9e-05 22.3 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS51095.1 - 0.00029 20.6 0.0 0.00062 19.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AAS51095.1 - 0.013 15.0 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CLASP_N PF12348.3 AAS51096.1 - 1.2e-08 34.6 0.0 3.4e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 CLASP N terminal TPR_MLP1_2 PF07926.7 AAS51096.1 - 5.1e-05 23.0 1.1 5.1e-05 23.0 0.8 3.3 4 0 0 4 4 4 1 TPR/MLP1/MLP2-like protein DUF641 PF04859.7 AAS51096.1 - 0.0024 17.6 4.2 0.0024 17.6 2.9 2.3 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) Myosin_tail_1 PF01576.14 AAS51096.1 - 0.0035 15.1 6.8 0.0073 14.0 4.7 1.4 1 0 0 1 1 1 1 Myosin tail HEAT PF02985.17 AAS51096.1 - 0.0052 16.7 0.0 0.45 10.7 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat IncA PF04156.9 AAS51096.1 - 0.0058 16.2 0.7 0.0058 16.2 0.5 2.8 3 0 0 3 3 3 1 IncA protein PIN_4 PF13638.1 AAS51096.1 - 0.026 14.6 0.2 0.026 14.6 0.1 2.7 3 0 0 3 3 3 0 PIN domain Filo_VP35 PF02097.10 AAS51096.1 - 0.048 12.8 3.5 0.55 9.3 0.7 2.4 2 0 0 2 2 2 0 Filoviridae VP35 APG6 PF04111.7 AAS51096.1 - 0.39 9.7 9.5 1.8 7.5 6.6 2.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 AAS51096.1 - 1.3 9.2 7.8 0.074 13.3 0.5 2.3 3 0 0 3 3 3 0 AAA domain Thioredoxin PF00085.15 AAS51097.1 - 3.6e-32 110.1 0.4 4e-32 110.0 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AAS51097.1 - 7.9e-09 35.7 0.3 1.2e-07 31.8 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AAS51097.1 - 3.5e-08 33.4 0.1 3.7e-06 26.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 AAS51097.1 - 1.3e-06 28.0 0.2 2.6e-06 27.1 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.11 AAS51097.1 - 2.8e-05 23.6 0.1 3e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_9 PF14595.1 AAS51097.1 - 6.1e-05 22.5 0.0 6.4e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 AAS51097.1 - 0.0004 19.9 0.3 0.0013 18.3 0.1 1.7 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 AAS51097.1 - 0.00067 19.6 0.2 0.0016 18.4 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like DUF2847 PF11009.3 AAS51097.1 - 0.0011 18.5 0.1 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Thioredoxin_3 PF13192.1 AAS51097.1 - 0.0061 16.3 0.1 0.0082 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_6 PF13848.1 AAS51097.1 - 0.011 15.4 0.2 0.015 15.1 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain HyaE PF07449.6 AAS51097.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE TraF PF13728.1 AAS51097.1 - 0.05 13.0 0.1 0.069 12.6 0.1 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.19 AAS51097.1 - 0.099 12.6 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin HAD PF12710.2 AAS51098.1 - 2.1e-17 63.9 0.0 3e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AAS51098.1 - 2.8e-14 54.0 1.6 1.7e-13 51.5 1.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AAS51098.1 - 8.3e-07 28.8 0.1 1e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AAS51098.1 - 1.1e-05 25.7 0.4 0.0016 18.6 0.0 2.4 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 AAS51098.1 - 0.00056 19.1 0.0 0.001 18.2 0.0 1.4 1 1 0 1 1 1 1 Putative Phosphatase DUF705 PF05152.7 AAS51098.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) ETF PF01012.16 AAS51099.1 - 9.7e-33 113.1 5.3 1.4e-32 112.7 3.7 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Mvb12 PF09452.5 AAS51100.1 - 9.1e-40 134.7 0.0 1e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 HAUS6_N PF14661.1 AAS51100.1 - 0.14 11.5 0.1 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus 3-HAO PF06052.7 AAS51101.1 - 2.4e-61 205.5 0.0 2.7e-61 205.3 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 AAS51101.1 - 8.7e-07 28.3 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 AAS51101.1 - 0.00078 18.9 0.1 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 AAS51101.1 - 0.00093 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain FYVE PF01363.16 AAS51101.1 - 0.014 15.2 1.4 0.023 14.5 1.0 1.3 1 0 0 1 1 1 0 FYVE zinc finger zf-B_box PF00643.19 AAS51101.1 - 0.26 11.2 2.9 0.3 11.0 0.2 2.1 2 0 0 2 2 2 0 B-box zinc finger Aldolase_II PF00596.16 AAS51102.1 - 2e-43 148.1 0.0 2.4e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain LSM PF01423.17 AAS51103.1 - 1.4e-11 43.7 0.0 1.9e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain Mer2 PF09074.5 AAS51104.2 - 3.9e-54 183.4 0.0 9.1e-54 182.2 0.0 1.5 1 1 0 1 1 1 1 Mer2 TelA PF05816.6 AAS51104.2 - 0.0027 16.4 1.0 0.0066 15.1 0.0 1.8 1 1 1 2 2 2 1 Toxic anion resistance protein (TelA) AAA_25 PF13481.1 AAS51105.1 - 4.7e-05 22.8 0.0 8.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AAS51105.1 - 0.00015 21.8 0.1 0.00024 21.1 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 AAS51105.1 - 0.00059 18.9 0.0 0.00097 18.2 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin SRP54 PF00448.17 AAS51105.1 - 0.0007 19.0 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 AAS51105.1 - 0.00097 19.0 0.2 0.024 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AAS51105.1 - 0.0019 17.9 1.2 0.017 14.8 0.0 2.8 3 0 0 3 3 3 1 Part of AAA domain AAA_17 PF13207.1 AAS51105.1 - 0.0058 17.4 0.0 0.015 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 AAS51105.1 - 0.044 12.6 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 AAS51105.1 - 0.045 13.8 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AAS51105.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 AAS51105.1 - 0.17 11.6 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 AAS51105.1 - 0.19 10.8 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 KaiC Acyl_CoA_thio PF02551.10 AAS51106.1 - 6.9e-16 58.0 0.0 9.3e-13 47.9 0.0 2.8 2 1 1 3 3 3 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 AAS51106.1 - 2.8e-13 50.2 0.0 7.9e-13 48.7 0.0 1.6 1 1 0 1 1 1 1 Thioesterase-like superfamily FTHFS PF01268.14 AAS51107.2 - 1.8e-255 848.2 0.1 2.5e-255 847.7 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 AAS51107.2 - 3.4e-61 205.0 0.2 3.4e-61 205.0 0.1 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 AAS51107.2 - 2.9e-37 127.2 0.0 6.7e-37 126.0 0.0 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Rotamase PF00639.16 AAS51108.1 - 1.1e-24 87.0 0.0 1.6e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 AAS51108.1 - 1.1e-16 61.1 0.0 1.4e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 AAS51108.1 - 1.5e-10 40.7 1.7 2.5e-10 40.0 1.2 1.3 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 AAS51108.1 - 1.6e-07 31.9 0.1 2.1e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 PPIC-type PPIASE domain alpha-hel2 PF14456.1 AAS51108.1 - 0.061 12.0 0.1 0.076 11.7 0.0 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 Rhodanese PF00581.15 AAS51109.1 - 6.9e-12 45.7 0.0 8.3e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain CTP_transf_2 PF01467.21 AAS51110.1 - 6.1e-24 84.8 0.0 9.9e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase ILVD_EDD PF00920.16 AAS51111.1 - 1.4e-206 686.9 0.1 1.7e-206 686.7 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family WD40 PF00400.27 AAS51112.1 - 9.5e-57 186.9 17.7 7e-07 28.8 0.0 10.1 9 0 0 9 9 9 9 WD domain, G-beta repeat VCBS PF13517.1 AAS51112.1 - 0.069 13.5 2.4 5.8 7.3 0.1 4.7 5 0 0 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_3 PF01764.20 AAS51114.1 - 7.1e-31 106.7 0.0 1.2e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 AAS51114.1 - 0.022 14.1 0.1 0.68 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Thioesterase PF00975.15 AAS51114.1 - 0.062 13.5 0.1 0.095 12.9 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 AAS51114.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_trans_1_4 PF13692.1 AAS51114.1 - 0.11 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 TPR_17 PF13431.1 AAS51115.1 - 0.00039 20.3 0.1 0.54 10.5 0.0 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 AAS51115.1 - 0.00091 19.6 2.8 7.6 7.4 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 AAS51115.1 - 0.0028 17.2 1.6 0.2 11.2 0.0 4.0 3 1 2 5 5 5 2 TPR repeat TPR_19 PF14559.1 AAS51115.1 - 0.0047 17.2 0.3 3.8 7.9 0.0 4.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 AAS51115.1 - 0.048 13.5 1.0 65 3.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 AAS51115.1 - 0.049 13.5 0.6 3.3 7.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Longin PF13774.1 AAS51115.1 - 0.061 12.8 0.1 10 5.7 0.0 2.7 2 0 0 2 2 2 0 Regulated-SNARE-like domain TPR_16 PF13432.1 AAS51115.1 - 4.3 8.1 8.1 13 6.5 0.1 5.0 6 1 0 6 6 6 0 Tetratricopeptide repeat SUI1 PF01253.17 AAS51116.1 - 5.9e-21 74.0 1.0 1.3e-20 72.9 0.7 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 CtsR PF05848.6 AAS51116.1 - 0.051 13.5 0.5 0.93 9.4 0.0 2.2 2 0 0 2 2 2 0 Firmicute transcriptional repressor of class III stress genes (CtsR) MethyltransfD12 PF02086.10 AAS51116.1 - 0.13 11.6 0.3 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase OmpH PF03938.9 AAS51116.1 - 0.4 10.5 5.5 0.69 9.8 3.8 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Cgr1 PF03879.9 AAS51116.1 - 4.3 7.5 15.5 0.21 11.7 6.1 2.0 2 0 0 2 2 2 0 Cgr1 family Calcipressin PF04847.7 AAS51117.1 - 5.7e-12 45.5 0.3 1e-11 44.7 0.1 1.4 2 0 0 2 2 2 1 Calcipressin COX5A PF02284.11 AAS51118.1 - 2e-50 169.2 1.3 2.5e-50 168.9 0.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF488 PF04343.8 AAS51118.1 - 0.035 14.4 0.7 0.43 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF488 Pyr_redox_2 PF07992.9 AAS51119.1 - 5.3e-29 101.5 0.1 6.2e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AAS51119.1 - 6.9e-18 64.8 0.0 8.8e-15 54.8 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AAS51119.1 - 8.2e-08 32.5 0.0 9.6e-05 22.5 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AAS51119.1 - 1.8e-05 23.8 0.5 0.51 9.1 0.1 3.8 4 0 0 4 4 4 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 AAS51119.1 - 2e-05 23.6 2.4 0.062 12.1 0.1 3.0 3 1 0 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.1 AAS51119.1 - 0.00025 21.2 0.0 0.1 12.8 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 AAS51119.1 - 0.00049 19.2 0.0 0.0086 15.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 AAS51119.1 - 0.00065 19.6 0.0 0.033 14.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AAS51119.1 - 0.0012 17.8 0.6 1.4 7.6 0.0 2.8 1 1 1 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 AAS51119.1 - 0.0023 18.0 0.1 2.2 8.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 AAS51119.1 - 0.0053 15.7 0.0 1 8.1 0.0 3.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 AAS51119.1 - 0.012 14.6 0.1 3.8 6.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 AAS51119.1 - 0.022 13.2 0.1 2.5 6.4 0.1 2.9 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.1 AAS51119.1 - 0.033 13.9 0.1 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 AAS51119.1 - 0.046 12.7 0.4 6.1 5.8 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase PX PF00787.19 AAS51120.2 - 4.7e-15 55.3 0.0 5.7e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 PX domain Aldo_ket_red PF00248.16 AAS51121.1 - 1.7e-48 164.8 0.0 2.3e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PQ-loop PF04193.9 AAS51122.1 - 2.9e-37 126.0 6.3 9.5e-19 66.7 0.8 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 AAS51122.1 - 0.051 13.4 0.2 0.051 13.4 0.1 2.9 3 1 0 3 3 3 0 Sugar efflux transporter for intercellular exchange Pkinase PF00069.20 AAS51124.1 - 6e-70 235.3 0.0 9.7e-70 234.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51124.1 - 1.3e-52 178.4 0.0 2.4e-52 177.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS51124.1 - 1.5e-08 33.9 0.1 1.2e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 AAS51124.1 - 0.0049 16.6 0.1 3.1 7.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family SIMPL PF04402.9 AAS51124.1 - 0.52 10.1 8.0 4.8 6.9 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF541) PV-1 PF06637.6 AAS51125.1 - 0.021 13.3 1.0 0.035 12.6 0.7 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DSPc PF00782.15 AAS51126.2 - 2.3e-26 91.9 0.1 2.1e-25 88.8 0.1 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AAS51126.2 - 0.0016 17.8 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Yippee-Mis18 PF03226.9 AAS51126.2 - 0.026 14.5 1.1 0.2 11.6 0.7 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Trm112p PF03966.11 AAS51126.2 - 0.036 14.4 0.0 0.087 13.2 0.0 1.7 1 1 0 1 1 1 0 Trm112p-like protein Elf1 PF05129.8 AAS51126.2 - 0.056 13.1 0.9 6.5 6.5 0.0 2.9 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like PTPlike_phytase PF14566.1 AAS51126.2 - 0.067 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Apc15p PF05841.6 AAS51127.2 - 4.1e-11 43.7 0.4 7.8e-11 42.7 0.3 1.5 1 0 0 1 1 1 1 Apc15p protein DUF1748 PF08520.5 AAS51128.2 - 3.3e-21 74.7 0.1 4.1e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) WD40 PF00400.27 AAS51129.2 - 3.3e-14 52.1 0.0 2.3e-06 27.2 0.0 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat Lactonase PF10282.4 AAS51129.2 - 0.005 15.9 0.0 0.053 12.6 0.0 2.5 2 1 0 3 3 3 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 AAS51129.2 - 0.079 11.2 0.0 3 6.0 0.0 2.8 2 1 0 3 3 3 0 Cytochrome D1 heme domain DUF3312 PF11768.3 AAS51129.2 - 0.18 9.9 0.0 0.47 8.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) AAA_12 PF13087.1 AAS51130.2 - 1.3e-56 191.1 0.0 2.3e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AAS51130.2 - 1.4e-54 185.1 0.0 2.6e-54 184.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AAS51130.2 - 5.7e-16 58.0 0.1 5.6e-15 54.8 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 AAS51130.2 - 1.2e-11 44.5 0.0 3e-08 33.5 0.0 3.6 2 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 AAS51130.2 - 2.1e-07 30.7 0.1 0.17 11.3 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 AAS51130.2 - 4.2e-05 23.7 0.1 0.003 17.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain UvrD-helicase PF00580.16 AAS51130.2 - 0.00017 21.0 0.0 0.00097 18.5 0.0 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 AAS51130.2 - 0.00022 20.5 0.0 0.047 12.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Helicase_RecD PF05127.9 AAS51130.2 - 0.00077 19.1 0.0 0.007 16.0 0.0 2.8 3 1 0 3 3 2 1 Helicase AAA_16 PF13191.1 AAS51130.2 - 0.0012 18.8 0.7 0.0075 16.2 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain TrwB_AAD_bind PF10412.4 AAS51130.2 - 0.0015 17.2 0.0 0.0027 16.3 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 AAS51130.2 - 0.0029 17.0 0.0 0.094 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain ResIII PF04851.10 AAS51130.2 - 0.0034 17.2 0.0 0.01 15.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 AAS51130.2 - 0.0037 16.6 0.0 0.011 15.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein UvrD_C_2 PF13538.1 AAS51130.2 - 0.0043 17.1 0.0 0.021 14.9 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Zot PF05707.7 AAS51130.2 - 0.0061 16.0 0.0 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) Flavi_DEAD PF07652.9 AAS51130.2 - 0.0071 16.1 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA PF00004.24 AAS51130.2 - 0.016 15.3 0.1 0.14 12.3 0.0 2.6 3 0 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 AAS51130.2 - 0.017 14.1 1.0 0.1 11.5 0.0 2.5 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 AAS51130.2 - 0.021 15.6 0.3 0.098 13.4 0.1 2.4 2 1 0 2 2 1 0 AAA domain UvrD_C PF13361.1 AAS51130.2 - 0.022 14.2 0.1 1.1 8.6 0.1 2.3 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain MobB PF03205.9 AAS51130.2 - 0.025 14.3 0.0 0.07 12.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DEAD PF00270.24 AAS51130.2 - 0.028 13.9 0.0 0.29 10.6 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase Glyco_transf_4 PF13439.1 AAS51130.2 - 0.029 14.0 0.1 6.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Glycosyltransferase Family 4 ArgK PF03308.11 AAS51130.2 - 0.032 13.0 0.0 0.066 11.9 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 AAS51130.2 - 0.033 13.5 0.0 0.11 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 AAS51130.2 - 0.034 13.5 0.0 0.069 12.5 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.14 AAS51130.2 - 0.054 12.9 0.1 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 AAS51130.2 - 0.067 13.0 0.0 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 AAS51130.2 - 0.12 11.2 0.0 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase DUF258 PF03193.11 AAS51130.2 - 0.14 11.3 0.0 0.33 10.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mt_ATP-synt_D PF05873.7 AAS51131.1 - 4.4e-15 55.6 0.5 5.5e-15 55.3 0.4 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) EzrA PF06160.7 AAS51131.1 - 0.0023 16.1 0.5 0.0059 14.8 0.2 1.6 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA LTXXQ PF07813.7 AAS51131.1 - 0.0072 16.7 3.5 1.5 9.3 0.1 2.1 1 1 1 2 2 2 2 LTXXQ motif family protein Dor1 PF04124.7 AAS51131.1 - 0.048 12.1 0.6 0.058 11.8 0.4 1.1 1 0 0 1 1 1 0 Dor1-like family T2SM_b PF10741.4 AAS51131.1 - 0.075 12.6 0.1 0.16 11.6 0.1 1.7 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b Seryl_tRNA_N PF02403.17 AAS51131.1 - 9.2 6.3 6.8 22 5.0 0.6 2.7 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Fungal_trans PF04082.13 AAS51132.2 - 8e-20 70.7 0.9 1.5e-19 69.9 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS51132.2 - 1.9e-09 37.2 5.5 3.6e-09 36.3 3.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Npa1 PF11707.3 AAS51133.1 - 1.3e-103 346.4 3.4 1.9e-103 345.9 0.7 2.5 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Fungal_trans PF04082.13 AAS51135.2 - 3.1e-28 98.3 1.3 4.9e-28 97.7 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS51135.2 - 1.2e-05 25.1 8.2 2.3e-05 24.1 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARPC4 PF05856.7 AAS51136.2 - 1.7e-69 232.5 3.0 1.9e-69 232.4 2.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Metallophos PF00149.23 AAS51137.1 - 5.7e-15 55.2 2.7 6.1e-14 51.8 1.9 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AAS51137.1 - 5.6e-06 26.2 0.0 5e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Suf PF05843.9 AAS51139.3 - 0.00055 19.7 0.0 0.67 9.6 0.0 2.6 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) LRR_4 PF12799.2 AAS51140.1 - 0.00058 19.4 13.0 0.5 10.0 0.0 5.4 6 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AAS51140.1 - 0.14 12.3 19.5 16 5.9 0.3 8.1 9 0 0 9 9 9 0 Leucine Rich repeat LRR_7 PF13504.1 AAS51140.1 - 1.1 9.7 16.2 37 5.1 0.1 7.0 6 1 1 7 7 7 0 Leucine rich repeat LRR_8 PF13855.1 AAS51140.1 - 6.3 6.6 16.8 1.6 8.5 1.0 5.6 5 1 0 5 5 5 0 Leucine rich repeat Ras PF00071.17 AAS51141.1 - 1.1e-48 164.6 0.0 1.2e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS51141.1 - 3.1e-14 53.5 0.0 4e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS51141.1 - 2e-07 30.3 0.0 3e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 AAS51141.1 - 0.00017 21.1 0.0 0.45 10.0 0.0 2.7 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 AAS51141.1 - 0.0036 16.7 0.0 0.055 12.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AAS51141.1 - 0.028 13.6 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_21 PF13304.1 AAS51141.1 - 0.18 11.7 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain NST1 PF13945.1 AAS51142.2 - 4.2e-15 56.3 4.3 4.2e-15 56.3 3.0 4.9 4 1 1 5 5 5 1 Salt tolerance down-regulator CAF-1_p150 PF11600.3 AAS51142.2 - 0.0012 18.3 43.5 0.0012 18.3 30.2 4.0 3 1 1 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal N2227 PF07942.7 AAS51143.1 - 9.6e-108 359.2 0.1 1.2e-107 358.9 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Ras PF00071.17 AAS51144.1 - 3.4e-60 202.1 0.0 3.9e-60 201.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS51144.1 - 3.3e-21 75.9 0.0 4.8e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS51144.1 - 1e-17 63.9 0.0 1.2e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AAS51144.1 - 9.1e-09 34.7 0.0 1.1e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AAS51144.1 - 1.3e-07 31.2 0.0 2.3e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AAS51144.1 - 7.9e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PP2C PF00481.16 AAS51145.1 - 2e-44 151.9 0.0 3e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 AAS51145.1 - 2.2e-05 23.9 0.0 0.0001 21.8 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C zf-CCCH PF00642.19 AAS51146.1 - 2.3e-05 23.9 1.3 4.1e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2183 PF09949.4 AAS51147.2 - 8.4e-33 112.3 0.0 1e-31 108.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Mem_trans PF03547.13 AAS51148.2 - 3.8e-70 236.1 0.0 9.6e-70 234.8 0.0 1.6 1 1 0 1 1 1 1 Membrane transport protein AMP-binding PF00501.23 AAS51149.2 - 1.8e-38 132.0 0.0 5.9e-15 54.5 0.0 5.0 5 0 0 5 5 5 5 AMP-binding enzyme DMAP_binding PF06464.6 AAS51149.2 - 7.3e-06 26.5 0.0 2.8e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 DMAP1-binding Domain Arf PF00025.16 AAS51150.1 - 2e-70 235.5 0.1 2.3e-70 235.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 AAS51150.1 - 8.8e-14 51.2 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 AAS51150.1 - 3.1e-13 49.2 0.6 9.6e-09 34.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 AAS51150.1 - 3.1e-13 49.3 0.0 3.8e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 AAS51150.1 - 1.8e-10 40.3 0.0 2.2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AAS51150.1 - 1.3e-09 38.6 0.0 1.8e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AAS51150.1 - 5.1e-06 26.4 0.0 6.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Rib_5-P_isom_A PF06026.9 AAS51151.1 - 3e-54 182.9 0.0 3.7e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 AAS51151.1 - 0.0033 17.0 0.0 0.084 12.5 0.0 2.2 1 1 0 1 1 1 1 DeoR C terminal sensor domain Ribosomal_S7e PF01251.13 AAS51152.1 - 2.2e-82 275.1 2.3 2.6e-82 274.8 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF4265 PF14085.1 AAS51152.1 - 0.081 12.6 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) SRP40_C PF05022.7 AAS51154.2 - 2.6e-30 104.7 5.0 5.5e-30 103.6 3.4 1.6 1 0 0 1 1 1 1 SRP40, C-terminal domain AA_permease_2 PF13520.1 AAS51155.2 - 9.4e-68 228.6 39.3 1.2e-67 228.3 27.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2663 PF10864.3 AAS51155.2 - 8.8 6.5 5.8 16 5.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) ABC_tran PF00005.22 AAS51156.2 - 4.5e-58 195.4 0.7 4.8e-34 117.5 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 AAS51156.2 - 5.5e-50 170.3 35.1 2.7e-30 105.7 7.4 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 AAS51156.2 - 9.8e-11 42.1 2.2 2.9e-06 27.4 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_23 PF13476.1 AAS51156.2 - 1.9e-08 34.8 3.8 0.003 17.9 0.4 2.8 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 AAS51156.2 - 4.2e-08 32.6 7.6 0.003 16.8 2.4 4.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AAS51156.2 - 9.8e-07 28.2 0.2 0.0045 16.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 AAS51156.2 - 1.4e-05 24.3 0.0 0.068 12.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 AAS51156.2 - 6.6e-05 22.9 0.1 0.085 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 AAS51156.2 - 7.5e-05 22.6 0.1 0.027 14.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 AAS51156.2 - 0.00016 22.1 0.1 0.41 11.1 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 AAS51156.2 - 0.00029 20.3 0.0 0.049 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AAS51156.2 - 0.0015 17.4 0.0 1 8.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 AAS51156.2 - 0.0018 18.4 0.1 5.5 7.1 0.0 3.2 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 AAS51156.2 - 0.0019 18.0 0.1 1.3 8.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 AAS51156.2 - 0.0031 16.6 0.1 0.2 10.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 AAS51156.2 - 0.0058 17.4 0.2 2.6 8.8 0.1 3.1 3 0 0 3 3 2 1 AAA domain Adeno_IVa2 PF02456.10 AAS51156.2 - 0.0078 14.9 0.1 1.2 7.6 0.0 2.4 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_15 PF13175.1 AAS51156.2 - 0.011 14.7 2.3 0.093 11.7 0.0 2.7 2 1 0 3 3 3 0 AAA ATPase domain ATP_bind_1 PF03029.12 AAS51156.2 - 0.014 14.9 0.1 13 5.2 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA PF00004.24 AAS51156.2 - 0.015 15.4 0.2 14 5.8 0.0 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 AAS51156.2 - 0.016 14.9 0.8 3.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 AAS51156.2 - 0.02 14.3 0.2 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain Dynamin_N PF00350.18 AAS51156.2 - 0.023 14.4 0.5 2.3 8.0 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.1 AAS51156.2 - 0.026 14.1 0.7 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 AAS51156.2 - 0.068 12.6 0.0 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 AAS51156.2 - 0.16 11.4 0.0 25 4.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 AAS51156.2 - 0.21 10.3 0.3 0.62 8.7 0.0 1.8 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 AAS51156.2 - 0.21 11.0 0.1 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 AAS51156.2 - 0.23 11.3 0.0 27 4.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.17 AAS51157.1 - 7.4e-16 57.5 4.7 3.3e-10 39.4 0.2 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS51157.1 - 9.6e-11 41.5 0.5 2e-05 24.5 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS51157.1 - 0.029 14.2 0.3 0.81 9.5 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L7Ae PF01248.21 AAS51158.1 - 1.2e-22 79.2 0.3 2.1e-22 78.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 AAS51158.1 - 0.0026 17.6 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 FGGY_C PF02782.11 AAS51159.2 - 3.4e-73 245.5 0.5 5.1e-73 244.9 0.3 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 AAS51159.2 - 1.1e-53 182.1 0.0 1.5e-44 152.1 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 AAS51159.2 - 0.039 13.2 0.1 0.15 11.3 0.0 2.0 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family MIP PF00230.15 AAS51160.2 - 8.8e-59 198.7 6.3 1.2e-58 198.2 4.4 1.2 1 0 0 1 1 1 1 Major intrinsic protein PrgI PF12666.2 AAS51160.2 - 0.012 15.7 2.4 0.081 13.0 0.4 2.5 2 0 0 2 2 2 0 PrgI family protein V-SNARE_C PF12352.3 AAS51161.2 - 1.2e-19 70.0 11.4 1.8e-16 59.9 0.9 2.5 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus RseA_N PF03872.8 AAS51161.2 - 0.00029 21.0 1.4 0.00061 20.0 1.0 1.6 1 0 0 1 1 1 1 Anti sigma-E protein RseA, N-terminal domain Sec34 PF04136.10 AAS51161.2 - 0.01 15.5 4.1 0.012 15.2 1.9 1.9 1 1 0 1 1 1 0 Sec34-like family ALIX_LYPXL_bnd PF13949.1 AAS51161.2 - 0.027 13.4 14.4 0.13 11.2 4.3 2.3 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV Sec20 PF03908.8 AAS51161.2 - 0.12 12.0 3.8 0.16 11.7 0.1 2.4 2 1 0 2 2 2 0 Sec20 DUF4239 PF14023.1 AAS51161.2 - 0.91 8.8 4.5 0.73 9.1 0.4 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF4239) TBPIP PF07106.8 AAS51161.2 - 1.9 8.0 7.3 0.6 9.6 0.7 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Autophagy_act_C PF03987.10 AAS51162.2 - 5e-08 32.9 0.3 8.2e-08 32.3 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Fer2_3 PF13085.1 AAS51163.1 - 6.3e-34 116.1 0.1 1e-33 115.4 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 AAS51163.1 - 1.9e-11 44.1 7.4 1.9e-11 44.1 5.1 2.3 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 AAS51163.1 - 2e-09 37.3 6.1 2e-09 37.3 4.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 AAS51163.1 - 8.6e-05 22.2 6.2 8.6e-05 22.2 4.3 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 AAS51163.1 - 0.00023 21.5 3.6 0.00023 21.5 2.5 2.8 1 1 2 3 3 3 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AAS51163.1 - 0.00089 19.4 8.7 0.034 14.4 0.2 3.3 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 AAS51163.1 - 0.0045 16.7 4.9 0.0078 15.9 0.8 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 AAS51163.1 - 0.02 15.2 9.3 0.02 15.2 6.4 2.9 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 AAS51163.1 - 0.27 11.8 0.1 0.27 11.8 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_16 PF13484.1 AAS51163.1 - 6.2 7.6 12.2 6.5 7.5 0.5 3.5 3 1 0 3 3 3 0 4Fe-4S double cluster binding domain DUF1162 PF06650.7 AAS51164.2 - 5.3e-86 288.2 0.5 3.6e-84 282.2 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 AAS51164.2 - 6.7e-41 138.5 0.1 2.5e-40 136.7 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Nnf1 PF03980.9 AAS51164.2 - 0.32 11.0 3.9 6.2 6.8 0.0 3.0 3 0 0 3 3 3 0 Nnf1 Ecm29 PF13001.2 AAS51165.2 - 7e-131 437.1 0.1 2.4e-130 435.4 0.0 2.0 2 0 0 2 2 2 1 Proteasome stabiliser HEAT PF02985.17 AAS51165.2 - 4.8e-13 47.9 0.5 0.091 12.8 0.0 8.2 6 0 0 6 6 6 2 HEAT repeat Vac14_Fab1_bd PF12755.2 AAS51165.2 - 0.00024 21.4 0.1 0.18 12.2 0.0 4.7 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region DUF1546 PF07571.8 AAS51165.2 - 0.0016 18.4 0.2 1.8 8.7 0.0 5.0 5 0 0 5 5 5 1 Protein of unknown function (DUF1546) ubiquitin PF00240.18 AAS51166.1 - 3.1e-169 548.6 31.3 1.6e-33 113.9 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 AAS51166.1 - 3.7e-97 318.0 28.4 6.2e-19 67.4 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AAS51166.1 - 1.7e-29 101.8 15.8 0.00021 21.4 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Telomere_Sde2 PF13019.1 AAS51166.1 - 8.4e-27 93.8 3.0 0.0014 18.3 0.0 5.0 5 0 0 5 5 5 5 Telomere stability and silencing Rad60-SLD_2 PF13881.1 AAS51166.1 - 6.9e-17 61.3 5.0 0.17 11.7 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AAS51166.1 - 1.1e-16 60.7 4.7 0.18 12.0 0.0 5.2 1 1 4 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 AAS51166.1 - 2.4e-13 49.9 0.0 2 8.4 0.0 5.9 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 AAS51166.1 - 7.9e-08 31.6 1.4 2.8 7.0 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase TUG-UBL1 PF11470.3 AAS51166.1 - 2e-07 30.8 9.3 6.4 6.7 0.0 5.2 5 0 0 5 5 5 5 GLUT4 regulating protein TUG FlgD_ig PF13860.1 AAS51166.1 - 1.6e-05 24.5 8.5 19 5.1 0.0 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Big_3_3 PF13750.1 AAS51166.1 - 0.00013 21.3 0.0 65 2.8 0.0 4.9 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 AAS51166.1 - 0.00024 19.5 18.5 3.1 5.9 0.2 6.7 6 4 0 6 6 6 4 Plexin cytoplasmic RasGAP domain ACT_4 PF13291.1 AAS51166.1 - 0.00038 20.7 1.5 1.4e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ACT domain CTDII PF01556.13 AAS51166.1 - 0.019 14.8 19.9 11 6.0 0.2 5.4 1 1 4 5 5 5 0 DnaJ C terminal domain Tash_PEST PF07708.6 AAS51166.1 - 0.026 14.4 38.3 4.5 7.3 1.2 5.4 5 0 0 5 5 5 0 Tash protein PEST motif GABP-alpha PF11620.3 AAS51166.1 - 0.061 13.3 11.8 63 3.6 0.1 5.0 5 0 0 5 5 5 0 GA-binding protein alpha chain FERM_N PF09379.5 AAS51166.1 - 0.16 11.9 17.3 58 3.8 0.1 7.0 5 5 0 5 5 5 0 FERM N-terminal domain DUF3781 PF12636.2 AAS51166.1 - 0.79 9.7 11.2 1.3e+02 2.5 0.1 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) ENTH PF01417.15 AAS51167.1 - 1.5e-28 99.2 0.0 1.8e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 AAS51167.1 - 0.038 12.6 0.1 0.053 12.2 0.1 1.1 1 0 0 1 1 1 0 ANTH domain SOG2 PF10428.4 AAS51167.1 - 0.04 12.5 0.3 0.067 11.8 0.1 1.4 1 1 0 1 1 1 0 RAM signalling pathway protein VHS PF00790.14 AAS51167.1 - 0.082 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 VHS domain DUF3418 PF11898.3 AAS51167.1 - 0.13 10.6 0.0 0.16 10.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Prp19 PF08606.6 AAS51168.1 - 8.5e-32 108.7 1.1 1.6e-31 107.8 0.8 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 AAS51168.1 - 0.003 17.4 0.1 0.0074 16.2 0.0 1.6 1 0 0 1 1 1 1 U-box domain DUF3435 PF11917.3 AAS51168.1 - 0.039 12.6 0.4 0.066 11.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) zf-Nse PF11789.3 AAS51168.1 - 0.091 12.2 0.1 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cys_Met_Meta_PP PF01053.15 AAS51169.1 - 4.7e-119 397.1 0.0 5.4e-119 396.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Fungal_trans PF04082.13 AAS51170.2 - 2.8e-08 32.9 0.1 5.3e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS51170.2 - 3.7e-07 29.9 11.2 8.2e-07 28.8 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 AAS51171.1 - 5.2e-14 51.6 9.7 1.2e-06 28.5 0.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS51171.1 - 2.4e-11 43.1 7.3 7.4e-05 22.8 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AAS51171.1 - 1.2e-08 34.8 12.0 4.5e-07 29.8 0.6 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AAS51171.1 - 4.2e-06 26.7 12.0 0.0013 18.7 0.3 3.0 3 0 0 3 3 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 AAS51171.1 - 0.001 19.1 0.9 0.0019 18.2 0.6 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 AAS51171.1 - 0.0014 18.3 5.3 0.22 11.2 0.2 2.5 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_6 PF13912.1 AAS51171.1 - 0.0061 16.4 0.3 0.0061 16.4 0.2 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 AAS51171.1 - 0.0075 16.4 13.3 0.089 13.0 0.3 3.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-DBF PF07535.7 AAS51171.1 - 0.024 14.3 2.8 3.8 7.2 0.1 2.7 2 0 0 2 2 2 0 DBF zinc finger PyrI_C PF02748.10 AAS51171.1 - 0.062 12.7 3.8 0.85 9.1 0.1 3.1 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.2 AAS51171.1 - 0.1 12.7 3.5 3.6 7.7 0.3 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 AAS51171.1 - 0.12 12.0 7.1 2 8.1 0.1 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-CHCC PF10276.4 AAS51171.1 - 0.37 10.6 5.5 0.8 9.5 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger domain DUF629 PF04780.7 AAS51171.1 - 0.97 7.8 3.7 3.4 6.0 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Mnd1 PF03962.10 AAS51172.2 - 2.1e-54 184.0 2.9 2.4e-54 183.8 2.0 1.0 1 0 0 1 1 1 1 Mnd1 family AIP3 PF03915.8 AAS51172.2 - 0.0021 17.0 1.5 0.0025 16.8 1.0 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 TBPIP PF07106.8 AAS51172.2 - 0.0037 16.8 3.5 0.018 14.6 2.5 1.9 1 1 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DsrD PF08679.6 AAS51172.2 - 0.0073 16.2 0.3 0.018 15.0 0.2 1.7 1 0 0 1 1 1 1 Dissimilatory sulfite reductase D (DsrD) Hemerythrin PF01814.18 AAS51172.2 - 0.043 13.9 2.4 0.15 12.2 0.2 2.4 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain DUF1768 PF08719.6 AAS51172.2 - 0.089 12.5 2.1 0.21 11.3 1.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1768) Cep57_MT_bd PF06657.8 AAS51172.2 - 0.1 12.5 3.2 3.3 7.7 0.1 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Syntaxin-6_N PF09177.6 AAS51172.2 - 0.15 12.4 1.0 0.95 9.9 0.1 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.17 AAS51172.2 - 0.18 11.8 4.1 0.17 11.9 1.0 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ArfGap PF01412.13 AAS51173.1 - 8.3e-29 99.7 0.0 8.3e-29 99.7 0.0 2.7 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf DUF2309 PF10070.4 AAS51173.1 - 0.049 11.7 12.7 0.069 11.2 8.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) DUF3543 PF12063.3 AAS51174.1 - 2.9e-65 219.8 1.3 2.5e-64 216.7 0.9 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 AAS51174.1 - 2.7e-59 200.4 0.0 6e-59 199.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51174.1 - 2.4e-43 148.1 0.0 4.7e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS51174.1 - 0.029 13.3 0.0 0.41 9.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.20 AAS51175.2 - 3.4e-54 183.7 0.0 1.2e-53 181.9 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51175.2 - 3e-26 92.0 0.2 1.4e-24 86.6 0.1 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS51175.2 - 0.0016 17.4 0.0 0.49 9.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Vfa1 PF08432.5 AAS51176.1 - 8.2e-42 143.2 0.6 9.4e-42 143.0 0.4 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Sas10_Utp3 PF04000.10 AAS51177.1 - 2e-12 47.1 0.2 5.7e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Rab5-bind PF09311.6 AAS51177.1 - 0.74 9.6 7.4 2.4 8.0 0.1 3.2 3 0 0 3 3 3 0 Rabaptin-like protein Ribosomal_S8e PF01201.17 AAS51178.1 - 8.3e-41 139.2 7.4 4.5e-40 136.8 5.1 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e HPD PF05044.7 AAS51178.1 - 0.05 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Homeo-prospero domain LCCL PF03815.14 AAS51180.2 - 1.9e-11 43.7 0.0 3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Sec6 PF06046.8 AAS51181.2 - 2.2e-157 524.6 15.0 2.7e-157 524.2 10.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 P22_AR_C PF10548.4 AAS51181.2 - 0.013 15.3 0.5 0.19 11.6 0.0 2.7 2 0 0 2 2 2 0 P22AR C-terminal domain Tctex-1 PF03645.8 AAS51182.2 - 2.6e-07 30.4 0.0 3.1e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 AAS51183.1 - 1.6e-13 50.6 4.0 1.6e-13 50.6 2.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Aldedh PF00171.17 AAS51184.1 - 5.7e-185 615.0 0.1 6.5e-185 614.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 AAS51184.1 - 0.01 14.5 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Ribosomal_S24e PF01282.14 AAS51185.1 - 4.8e-36 122.4 0.1 7.1e-36 121.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e SeleniumBinding PF11524.3 AAS51185.1 - 0.046 13.8 0.1 0.087 12.9 0.0 1.5 2 0 0 2 2 2 0 Selenium binding protein Yos1 PF08571.5 AAS51186.1 - 7.4e-31 106.0 2.6 8.2e-31 105.9 1.8 1.0 1 0 0 1 1 1 1 Yos1-like Statherin PF03875.8 AAS51186.1 - 0.26 11.1 0.8 0.44 10.4 0.5 1.4 1 1 0 1 1 1 0 Statherin Y_phosphatase PF00102.22 AAS51187.2 - 8.2e-53 179.1 0.0 1.2e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 AAS51187.2 - 6.7e-12 45.7 0.0 2.7e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 AAS51187.2 - 0.00066 19.2 0.0 0.0015 18.0 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 AAS51187.2 - 0.019 15.2 0.0 0.06 13.5 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family CRISPR_Cas2 PF09827.4 AAS51187.2 - 0.097 12.8 0.1 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 CRISPR associated protein Cas2 zf-CCHC PF00098.18 AAS51188.1 - 8.9e-06 25.3 42.2 0.00069 19.4 2.1 4.9 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.1 AAS51188.1 - 0.027 13.9 1.7 0.027 13.9 1.2 4.6 3 1 2 5 5 5 0 Zinc knuckle Elongin_A PF06881.6 AAS51188.1 - 0.33 11.3 0.1 0.33 11.3 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A tRNA-synt_2b PF00587.20 AAS51189.1 - 5.3e-47 159.6 0.3 1.1e-46 158.5 0.2 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AAS51189.1 - 1.8e-18 66.2 0.7 3.6e-18 65.2 0.2 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.9 AAS51189.1 - 1.7e-12 46.9 0.0 3.3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 AAS51189.1 - 2.5e-11 43.2 0.0 6.1e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 TGS domain DUF1689 PF07954.6 AAS51190.1 - 2.4e-46 157.3 0.0 3.8e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) Coatomer_E PF04733.9 AAS51191.1 - 7.6e-13 48.2 8.0 2e-12 46.9 5.6 1.6 1 1 0 1 1 1 1 Coatomer epsilon subunit GET2 PF08690.5 AAS51192.1 - 3.3e-100 335.2 0.0 3.9e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 DHO_dh PF01180.16 AAS51193.1 - 1.5e-97 326.0 0.0 2e-97 325.7 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 AAS51193.1 - 2.8e-06 26.4 0.0 0.0056 15.5 0.0 2.4 2 1 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.12 AAS51193.1 - 0.018 14.2 0.1 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 PcrB family YSIRK_signal PF04650.12 AAS51193.1 - 0.46 10.0 2.2 0.93 9.1 1.6 1.5 1 0 0 1 1 1 0 YSIRK type signal peptide BING4CT PF08149.6 AAS51194.1 - 2.5e-38 129.4 0.0 1e-35 121.0 0.0 3.4 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 AAS51194.1 - 1.1e-06 28.2 0.0 0.00035 20.3 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Med8 PF10232.4 AAS51194.1 - 0.017 14.6 3.2 0.037 13.5 2.2 1.5 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 PC_rep PF01851.17 AAS51195.1 - 7.2e-40 133.0 20.5 2.2e-05 24.4 0.0 10.0 11 0 0 11 11 11 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 AAS51195.1 - 2.5e-18 66.1 6.7 1.6e-13 50.7 0.0 4.7 3 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 AAS51195.1 - 6.6e-11 41.3 1.1 0.46 10.7 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 AAS51195.1 - 6.4e-09 36.0 3.5 0.037 14.5 0.0 5.5 3 2 2 5 5 5 3 HEAT-like repeat RICTOR_V PF14668.1 AAS51195.1 - 0.018 14.9 0.2 0.65 9.9 0.0 3.5 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Apc3 PF12895.2 AAS51195.1 - 1.2 9.3 5.8 1.3 9.1 0.1 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 2-Hacid_dh_C PF02826.14 AAS51196.1 - 5.7e-56 188.4 0.0 9.1e-56 187.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AAS51196.1 - 4.7e-36 123.1 0.0 6.3e-36 122.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AAS51196.1 - 2.7e-06 27.3 1.1 1.4e-05 24.9 0.2 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 AAS51196.1 - 9.9e-05 22.2 0.1 0.00019 21.2 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 AAS51196.1 - 0.002 17.5 0.0 0.0061 16.0 0.0 1.8 1 0 0 1 1 1 1 ACT domain Acetyltransf_1 PF00583.19 AAS51196.1 - 0.019 14.9 0.0 0.18 11.8 0.0 2.5 2 1 1 3 3 3 0 Acetyltransferase (GNAT) family IlvN PF07991.7 AAS51196.1 - 0.094 12.0 0.1 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain APH PF01636.18 AAS51197.2 - 7.9e-11 42.1 0.0 2.4e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AAS51197.2 - 0.024 14.2 0.1 0.088 12.3 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 AAS51197.2 - 0.045 12.7 0.0 7.7 5.5 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AAS51197.2 - 0.05 12.9 0.1 0.2 10.9 0.0 2.0 1 1 1 2 2 2 0 RIO1 family HORMA PF02301.13 AAS51199.1 - 4.3e-54 183.1 0.1 1.1e-53 181.8 0.1 1.7 1 0 0 1 1 1 1 HORMA domain PHD_2 PF13831.1 AAS51199.1 - 0.35 10.2 8.3 0.79 9.0 5.7 1.7 1 0 0 1 1 1 0 PHD-finger PHD PF00628.24 AAS51199.1 - 0.37 10.5 10.7 0.76 9.5 7.4 1.6 1 0 0 1 1 1 0 PHD-finger Peptidase_M24 PF00557.19 AAS51200.2 - 5.9e-51 172.9 0.0 8.8e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 AAS51200.2 - 8.5e-33 112.5 0.0 1.7e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain NAD_binding_8 PF13450.1 AAS51200.2 - 0.019 14.9 0.0 3.6 7.6 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PCI PF01399.22 AAS51201.1 - 6e-05 23.3 0.0 0.00024 21.3 0.0 2.0 2 0 0 2 2 2 1 PCI domain PPR_2 PF13041.1 AAS51202.1 - 7.7e-13 48.2 0.2 3.4e-11 42.9 0.0 3.4 3 1 1 4 4 4 1 PPR repeat family PPR PF01535.15 AAS51202.1 - 0.01 15.7 1.1 4.2 7.5 0.1 3.6 3 0 0 3 3 3 0 PPR repeat MAM33 PF02330.11 AAS51203.2 - 1.3e-36 126.2 7.7 1.9e-36 125.7 5.3 1.3 1 0 0 1 1 1 1 Mitochondrial glycoprotein tRNA-synt_His PF13393.1 AAS51203.2 - 0.015 14.3 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Elongin_A PF06881.6 AAS51203.2 - 0.018 15.4 0.1 0.032 14.6 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A FTCD_C PF04961.7 AAS51203.2 - 0.029 13.7 0.4 0.046 13.1 0.3 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Pmp3 PF01679.12 AAS51204.1 - 5.6e-17 61.1 6.7 7.9e-17 60.7 4.6 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator UPF0029 PF01205.14 AAS51206.1 - 5.3e-29 100.1 0.0 6.9e-29 99.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 FAD-oxidase_C PF02913.14 AAS51207.1 - 2.6e-51 174.3 0.0 3.5e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AAS51207.1 - 8.9e-37 125.6 0.1 1.5e-36 124.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain RNA_pol_I_TF PF04090.7 AAS51208.2 - 1.8e-73 246.1 1.2 2.6e-73 245.5 0.8 1.2 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor zf-RING_2 PF13639.1 AAS51209.2 - 1.2e-12 47.4 5.3 2.3e-12 46.5 3.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AAS51209.2 - 7.7e-10 38.7 2.3 1.6e-09 37.6 1.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 AAS51209.2 - 7.8e-10 38.2 4.2 1.5e-09 37.4 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS51209.2 - 8.6e-08 32.0 4.2 3.2e-07 30.2 2.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AAS51209.2 - 7e-07 28.8 3.0 1.3e-06 28.0 2.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AAS51209.2 - 1e-06 28.2 5.8 2.2e-06 27.1 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AAS51209.2 - 0.00067 19.3 2.6 0.00078 19.1 0.6 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 AAS51209.2 - 0.0013 18.4 0.8 0.0033 17.2 0.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger AKNA PF12443.3 AAS51209.2 - 0.01 15.8 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 0 AT-hook-containing transcription factor Prok-RING_4 PF14447.1 AAS51209.2 - 0.11 12.0 0.3 0.24 10.9 0.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 AAS51209.2 - 0.12 12.2 2.3 0.41 10.6 1.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 AAS51209.2 - 0.59 10.2 4.1 1.6 8.7 2.8 1.8 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 AAS51209.2 - 0.84 9.5 4.4 0.6 10.0 1.2 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 AAS51209.2 - 1 8.9 4.6 3 7.5 2.9 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain OPA3 PF07047.7 AAS51210.1 - 4.4e-36 123.6 0.9 5.2e-36 123.3 0.6 1.0 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) NYD-SP28_assoc PF14775.1 AAS51210.1 - 0.43 10.3 4.1 0.22 11.2 0.6 2.1 2 1 0 2 2 2 0 Sperm tail C-terminal domain DivIC PF04977.10 AAS51210.1 - 0.88 9.0 4.8 0.26 10.8 0.8 2.1 2 1 0 2 2 2 0 Septum formation initiator Atg14 PF10186.4 AAS51210.1 - 4.3 6.1 6.2 1.5 7.7 1.0 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4570 PF15134.1 AAS51210.1 - 4.6 7.1 8.8 5.4 6.9 1.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) Histone PF00125.19 AAS51211.1 - 8.5e-23 80.2 0.0 1.1e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AAS51211.1 - 5.6e-05 23.1 0.0 7.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF4 PF05236.9 AAS51212.1 - 6.6e-69 232.1 3.0 8.8e-69 231.7 2.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TFIID_30kDa PF03540.8 AAS51212.1 - 0.038 13.8 0.1 0.93 9.3 0.0 2.7 3 0 0 3 3 3 0 Transcription initiation factor TFIID 23-30kDa subunit RTC PF01137.16 AAS51213.1 - 5.7e-58 195.3 0.0 6.7e-58 195.1 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 AAS51213.1 - 2.6e-33 114.1 0.0 4.4e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PX PF00787.19 AAS51214.2 - 1.8e-19 69.5 0.0 5.8e-19 67.9 0.0 1.9 1 0 0 1 1 1 1 PX domain Enkurin PF13864.1 AAS51214.2 - 2.5 8.3 5.9 2.2 8.5 0.1 3.5 4 0 0 4 4 4 0 Calmodulin-binding FlxA PF14282.1 AAS51214.2 - 2.5 8.0 6.3 13 5.8 0.5 2.9 3 0 0 3 3 3 0 FlxA-like protein DUF2404 PF10296.4 AAS51215.2 - 0.00042 20.3 0.1 0.004 17.2 0.1 2.5 2 1 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Polyketide_cyc PF03364.15 AAS51216.1 - 3.9e-15 55.9 0.0 5e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SAP PF02037.22 AAS51217.1 - 2.3e-10 39.6 0.0 3.9e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 SAP domain CHCH PF06747.8 AAS51218.2 - 2.5e-05 24.0 4.2 3.5e-05 23.5 2.9 1.2 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.4 AAS51218.2 - 3e-05 24.2 7.0 3.6e-05 23.9 4.8 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Topoisom_I_N PF02919.10 AAS51220.2 - 1e-101 338.7 0.5 1e-101 338.7 0.3 2.6 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 AAS51220.2 - 6.2e-88 293.8 0.7 6.2e-88 293.8 0.5 3.6 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 AAS51220.2 - 2.8e-32 110.1 1.3 8.3e-32 108.6 0.9 1.9 1 0 0 1 1 1 1 C-terminal topoisomerase domain Pkinase PF00069.20 AAS51222.2 - 8.3e-73 244.7 0.2 2.1e-72 243.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51222.2 - 3.7e-39 134.3 0.0 6.1e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 AAS51222.2 - 6e-34 115.8 0.2 6.8e-17 61.2 0.1 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 AAS51222.2 - 7.4e-11 41.5 0.0 4.8e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AAS51222.2 - 0.0007 18.7 0.1 0.0021 17.1 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_3 PF08239.6 AAS51222.2 - 0.038 14.1 0.1 0.072 13.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain BBP1_N PF15271.1 AAS51222.2 - 0.25 11.7 4.4 0.52 10.6 0.1 2.4 2 0 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein RNA_pol_L_2 PF13656.1 AAS51223.1 - 2.5e-26 90.9 0.0 3.2e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 AAS51223.1 - 6.3e-11 41.2 0.0 8.9e-11 40.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Thymidylate_kin PF02223.12 AAS51223.1 - 0.04 13.2 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Thymidylate kinase PAH PF02671.16 AAS51224.1 - 1.5e-48 162.1 5.7 8.3e-19 66.9 0.4 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 AAS51224.1 - 4.1e-43 145.2 0.1 1e-42 143.9 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor zf-DHHC PF01529.15 AAS51225.2 - 9.4e-31 106.5 13.0 9.4e-31 106.5 9.0 1.7 1 1 1 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 AAS51225.2 - 0.079 12.7 0.4 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily HlyIII PF03006.15 AAS51226.2 - 1.5e-54 184.7 19.0 1.8e-54 184.5 13.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3671 PF12420.3 AAS51226.2 - 0.00073 19.4 2.8 0.0054 16.6 0.4 2.7 2 1 0 2 2 2 1 Protein of unknown function YoqO PF14037.1 AAS51226.2 - 0.24 11.5 5.6 0.5 10.4 2.8 2.3 1 1 1 2 2 2 0 YoqO-like protein DUF4231 PF14015.1 AAS51226.2 - 0.25 11.3 3.5 0.37 10.7 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DNA_pol_A_exo1 PF01612.15 AAS51227.2 - 6.5e-43 146.2 0.1 1.6e-42 144.9 0.1 1.7 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.7 AAS51227.2 - 4.4e-30 103.8 1.5 2e-29 101.7 0.3 2.5 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 AAS51227.2 - 5.9e-11 41.9 0.0 1.4e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Cyclin PF08613.6 AAS51228.1 - 5.2e-34 117.8 0.4 1.2e-33 116.5 0.3 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AAS51228.1 - 0.0019 17.7 0.0 0.0037 16.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ras PF00071.17 AAS51230.1 - 3e-58 195.7 0.2 3.5e-58 195.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS51230.1 - 4.6e-20 72.2 0.0 7.2e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS51230.1 - 2e-15 56.4 0.0 2.3e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AAS51230.1 - 2.5e-08 33.3 0.0 3.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AAS51230.1 - 1.6e-07 30.9 0.2 6.4e-06 25.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AAS51230.1 - 7.2e-06 25.9 0.0 1.1e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 AAS51230.1 - 2.7e-05 23.4 0.0 3.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 AAS51230.1 - 5.6e-05 23.2 0.0 9e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AAS51230.1 - 0.00044 20.2 0.0 0.0098 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 AAS51230.1 - 0.00059 19.4 0.2 0.02 14.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 AAS51230.1 - 0.0023 17.6 0.1 0.0064 16.2 0.0 1.7 2 0 0 2 2 2 1 NTPase MobB PF03205.9 AAS51230.1 - 0.0036 17.0 0.2 0.006 16.3 0.1 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 AAS51230.1 - 0.0039 16.6 0.0 0.015 14.7 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 AAS51230.1 - 0.0046 16.5 0.0 0.0099 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 AAS51230.1 - 0.007 15.5 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 AAS51230.1 - 0.0093 15.6 0.4 0.024 14.3 0.3 1.8 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 AAS51230.1 - 0.012 15.2 0.0 0.031 13.9 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 AAS51230.1 - 0.021 14.3 0.2 0.09 12.2 0.1 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 AAS51230.1 - 0.042 12.7 0.1 0.13 11.0 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.13 AAS51230.1 - 0.049 12.6 0.1 0.32 9.9 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_35 PF14516.1 AAS51230.1 - 0.061 11.9 0.0 0.28 9.7 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_10 PF12846.2 AAS51230.1 - 0.078 12.3 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 AAS51230.1 - 0.14 11.8 0.0 0.44 10.2 0.0 1.9 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Alg6_Alg8 PF03155.10 AAS51231.1 - 3.3e-155 517.4 29.0 4e-155 517.2 20.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TPR_11 PF13414.1 AAS51232.1 - 3.1e-23 81.2 12.8 5.9e-18 64.2 3.8 3.8 2 1 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 AAS51232.1 - 5.6e-18 63.7 7.1 1.8e-06 27.2 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 AAS51232.1 - 5.8e-17 60.1 11.9 3.2e-05 23.4 0.2 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 AAS51232.1 - 2.6e-07 29.9 6.4 0.063 13.1 0.1 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 AAS51232.1 - 3e-07 30.1 5.1 0.00022 21.1 0.2 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 AAS51232.1 - 3.8e-07 29.9 13.1 0.0019 18.1 0.1 3.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 AAS51232.1 - 5.2e-07 29.7 7.2 0.035 14.7 0.1 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 AAS51232.1 - 2e-06 28.0 6.1 0.00084 19.6 1.7 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AAS51232.1 - 2.1e-06 27.1 12.2 0.0049 16.5 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AAS51232.1 - 4.3e-06 27.2 11.4 0.00027 21.5 3.4 3.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 AAS51232.1 - 2.7e-05 23.9 2.2 0.01 15.6 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 AAS51232.1 - 0.00036 20.6 5.4 0.00075 19.5 3.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 AAS51232.1 - 0.00092 19.5 7.6 0.038 14.4 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 AAS51232.1 - 0.0082 16.4 5.2 0.071 13.4 3.5 2.2 1 1 0 1 1 1 1 Bacterial transcriptional activator domain T4SS PF07996.6 AAS51232.1 - 0.04 13.7 4.0 0.29 10.9 0.2 2.3 2 0 0 2 2 2 0 Type IV secretion system proteins DUF3856 PF12968.2 AAS51232.1 - 0.52 10.1 6.6 5.5 6.8 1.6 3.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) RPN7 PF10602.4 AAS51232.1 - 0.66 9.3 5.0 0.29 10.4 0.9 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.1 AAS51232.1 - 0.72 9.7 8.3 0.78 9.6 0.1 3.9 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 AAS51232.1 - 0.82 9.8 5.6 1.2 9.2 1.0 2.8 2 1 1 3 3 2 0 Tetratricopeptide repeat MIT PF04212.13 AAS51232.1 - 1.6 8.6 14.6 1.5 8.7 1.8 3.6 2 1 2 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 AAS51232.1 - 1.9 8.5 13.6 0.69 9.9 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 AAS51232.1 - 5.4 7.7 5.4 3.4 8.3 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat VPS9 PF02204.13 AAS51233.1 - 4.4e-17 62.0 0.1 1.6e-16 60.1 0.1 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 AAS51233.1 - 7.5e-06 26.1 0.0 0.0063 16.8 0.0 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AAS51233.1 - 0.00011 22.3 0.6 0.017 15.4 0.0 3.9 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 AAS51233.1 - 0.0016 18.5 3.6 2.9 8.3 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.25 AAS51233.1 - 0.011 15.5 1.7 0.12 12.2 0.0 3.7 5 0 0 5 5 5 0 Ankyrin repeat Ank_4 PF13637.1 AAS51233.1 - 0.022 15.2 1.8 1.7 9.2 0.0 3.8 3 2 1 4 4 4 0 Ankyrin repeats (many copies) HrpB7 PF09486.5 AAS51233.1 - 0.073 12.9 0.2 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF367 PF04034.8 AAS51234.1 - 8.2e-55 183.8 0.0 1.1e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 AAS51234.1 - 1e-15 57.0 0.2 1.7e-15 56.3 0.2 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DNA_ligase_A_M PF01068.16 AAS51235.1 - 2.9e-46 157.3 0.0 4.3e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 AAS51235.1 - 2.4e-11 43.7 0.0 4.3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus BRCT PF00533.21 AAS51235.1 - 1.6e-08 34.5 0.3 2.2e-05 24.5 0.0 3.2 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.10 AAS51235.1 - 7.2e-07 29.5 0.0 2.8e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 AAS51235.1 - 3.6e-05 23.5 1.9 0.11 12.1 0.1 3.2 2 1 0 2 2 2 2 mRNA capping enzyme, catalytic domain NPR2 PF06218.6 AAS51236.1 - 4.1e-175 582.5 7.0 4.1e-175 582.5 4.9 1.6 2 0 0 2 2 2 1 Nitrogen permease regulator 2 Afi1 PF07792.7 AAS51236.1 - 0.018 15.0 8.5 1.2 9.1 0.0 3.6 4 0 0 4 4 4 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Kinesin PF00225.18 AAS51237.1 - 1.3e-97 326.5 6.7 1.3e-97 326.5 4.6 3.6 2 1 0 2 2 2 1 Kinesin motor domain FliJ PF02050.11 AAS51237.1 - 0.0052 16.8 11.7 0.0052 16.8 8.1 3.6 3 1 0 3 3 3 1 Flagellar FliJ protein Apolipoprotein PF01442.13 AAS51237.1 - 0.7 9.3 20.5 0.026 14.0 6.2 3.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain IncA PF04156.9 AAS51237.1 - 0.84 9.2 36.2 0.036 13.6 9.2 3.8 4 0 0 4 4 4 0 IncA protein Laminin_II PF06009.7 AAS51237.1 - 4.1 7.1 29.5 0.023 14.4 5.9 4.2 3 2 1 4 4 4 0 Laminin Domain II Fcf1 PF04900.7 AAS51238.1 - 1.7e-32 111.5 1.1 1.7e-32 111.5 0.8 2.2 2 0 0 2 2 2 1 Fcf1 Peptidase_S8 PF00082.17 AAS51239.1 - 3e-53 180.8 6.1 4e-53 180.3 4.2 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 AAS51239.1 - 2e-08 34.6 0.0 4.9e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Lyase_1 PF00206.15 AAS51240.2 - 2.7e-114 381.5 0.0 3.4e-114 381.2 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 AAS51240.2 - 4.7e-24 84.2 0.0 9.6e-24 83.2 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus Mitochondr_Som1 PF11093.3 AAS51241.1 - 5.1e-24 83.8 0.4 6e-24 83.6 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 PGM_PMM_I PF02878.11 AAS51242.1 - 8.5e-19 67.4 0.0 5.4e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 AAS51242.1 - 2.7e-11 43.7 0.0 8.7e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 AAS51242.1 - 1.5e-10 40.9 0.1 3.4e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Kelch_3 PF13415.1 AAS51243.1 - 5.7e-32 109.1 7.1 6.3e-11 42.1 0.0 6.7 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.1 AAS51243.1 - 2.2e-30 104.1 7.9 7.9e-07 28.7 0.1 7.1 5 2 1 6 6 6 5 Galactose oxidase, central domain DUF4110 PF13422.1 AAS51243.1 - 1.2e-27 95.5 0.6 1.2e-27 95.5 0.4 4.0 3 2 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 AAS51243.1 - 5.8e-22 76.8 12.2 2e-06 27.7 0.2 6.0 4 2 2 6 6 6 5 Kelch motif Kelch_1 PF01344.20 AAS51243.1 - 6e-17 60.9 5.9 3.6e-06 26.4 0.1 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.1 AAS51243.1 - 2.7e-13 49.5 5.7 0.00037 20.3 0.1 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 AAS51243.1 - 2.8e-12 45.8 12.7 0.016 14.9 0.1 6.0 6 0 0 6 6 6 4 Kelch motif Cwf_Cwc_15 PF04889.7 AAS51243.1 - 3.4 7.3 41.7 0.078 12.6 4.3 3.3 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.27 AAS51244.1 - 5.4e-27 92.6 2.9 4.4e-06 26.3 0.8 5.8 5 1 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 AAS51244.1 - 1e-20 73.3 0.1 2.1e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Pyocin_S PF06958.7 AAS51244.1 - 0.0041 17.4 0.2 0.014 15.7 0.1 1.9 2 0 0 2 2 2 1 S-type Pyocin AATase PF07247.7 AAS51245.2 - 4.4e-10 38.7 0.0 3.6e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 Alcohol acetyltransferase Exonuc_VII_L PF02601.10 AAS51246.1 - 0.032 13.4 0.7 0.45 9.6 0.0 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF3719 PF12516.3 AAS51246.1 - 0.034 13.7 0.3 0.095 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) DNA_pol_phi PF04931.8 AAS51247.1 - 3.2e-105 352.6 20.8 8.3e-105 351.2 14.4 1.8 1 1 0 1 1 1 1 DNA polymerase phi NnrS PF05940.7 AAS51247.1 - 0.0019 17.1 0.2 0.003 16.5 0.2 1.2 1 0 0 1 1 1 1 NnrS protein UME PF08064.8 AAS51247.1 - 0.33 10.9 0.0 0.33 10.9 0.0 3.8 6 0 0 6 6 6 0 UME (NUC010) domain DUF2457 PF10446.4 AAS51247.1 - 5.9 5.5 16.8 8.9 4.9 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ATP-synt_Eps PF04627.8 AAS51248.1 - 7.3e-20 70.2 1.5 9e-20 69.9 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain ABC_membrane PF00664.18 AAS51249.2 - 3.9e-50 170.8 3.1 4.8e-50 170.4 2.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 AAS51249.2 - 3.6e-34 117.9 0.0 2.4e-33 115.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 AAS51249.2 - 7.1e-05 22.3 0.2 0.21 10.9 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain SMC_N PF02463.14 AAS51249.2 - 0.00028 20.1 0.0 0.012 14.8 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AAS51249.2 - 0.00031 20.8 0.0 0.76 9.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.1 AAS51249.2 - 0.001 19.2 0.1 0.02 15.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AAS51249.2 - 0.0014 19.4 0.0 0.0034 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AAS51249.2 - 0.0019 18.2 1.4 0.0036 17.3 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 AAS51249.2 - 0.0022 17.4 0.0 0.19 11.1 0.0 3.1 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_5 PF07728.9 AAS51249.2 - 0.0051 16.5 0.0 0.023 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 AAS51249.2 - 0.0074 15.7 0.0 0.2 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 AAS51249.2 - 0.01 15.9 0.0 0.13 12.4 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 AAS51249.2 - 0.015 14.8 0.0 0.043 13.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.4 AAS51249.2 - 0.022 13.3 0.1 0.057 12.0 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF258 PF03193.11 AAS51249.2 - 0.025 13.7 0.0 0.055 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DEAD PF00270.24 AAS51249.2 - 0.063 12.7 0.0 1.6 8.1 0.0 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase Bcl-2_BAD PF10514.4 AAS51249.2 - 0.095 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD KAR9 PF08580.5 AAS51250.1 - 1.2e-249 830.2 4.0 1.4e-249 830.0 2.7 1.0 1 0 0 1 1 1 1 Yeast cortical protein KAR9 Sp100 PF03172.8 AAS51250.1 - 0.042 13.8 1.6 0.17 11.8 0.5 2.4 1 1 1 2 2 2 0 Sp100 domain Baculo_PEP_C PF04513.7 AAS51250.1 - 0.31 10.8 6.2 1.3 8.7 0.7 3.1 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus PI-PLC-X PF00388.14 AAS51251.1 - 2.8e-47 159.7 0.0 1.5e-46 157.3 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 AAS51251.1 - 5.1e-39 132.9 0.0 3.6e-38 130.1 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_1 PF00036.27 AAS51251.1 - 3.6e-06 25.8 0.1 1.6e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 AAS51251.1 - 5.1e-05 22.7 0.6 0.0036 16.8 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 AAS51251.1 - 7.8e-05 22.7 0.1 0.00032 20.7 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 AAS51251.1 - 0.0012 18.5 1.0 0.015 15.1 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 AAS51251.1 - 0.0015 18.1 4.6 0.0025 17.4 0.2 2.9 2 1 0 2 2 2 1 EF hand EF-hand_4 PF12763.2 AAS51251.1 - 0.0045 16.6 0.1 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_like PF09279.6 AAS51251.1 - 0.005 16.8 2.3 0.77 9.8 0.1 3.0 2 1 1 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_5 PF13202.1 AAS51251.1 - 0.037 13.3 0.0 0.088 12.1 0.0 1.6 1 0 0 1 1 1 0 EF hand Gti1_Pac2 PF09729.4 AAS51252.1 - 0.35 10.7 3.0 0.22 11.3 0.1 1.9 1 1 1 2 2 2 0 Gti1/Pac2 family RrnaAD PF00398.15 AAS51253.1 - 1.6e-64 217.4 0.0 2e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 AAS51253.1 - 8.1e-10 38.7 0.0 1.5e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS51253.1 - 2.8e-06 27.8 0.0 6.6e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 AAS51253.1 - 5.4e-05 22.8 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 AAS51253.1 - 0.00055 19.3 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 AAS51253.1 - 0.0015 17.6 0.0 0.0045 16.0 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.11 AAS51253.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 AAS51253.1 - 0.0018 18.0 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AAS51253.1 - 0.0027 18.1 0.0 0.016 15.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS51253.1 - 0.003 17.1 0.0 0.0064 16.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 AAS51253.1 - 0.0035 16.4 0.1 0.048 12.7 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 AAS51253.1 - 0.0058 15.8 0.0 0.015 14.5 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_25 PF13649.1 AAS51253.1 - 0.084 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF917 PF06032.7 AAS51254.2 - 4.8e-110 367.4 0.0 8e-110 366.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 AAS51254.2 - 6.4e-48 163.3 3.5 7.6e-46 156.5 1.5 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 AAS51254.2 - 3e-35 121.3 0.2 4.8e-33 114.1 0.0 2.9 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 AAS51254.2 - 0.0038 15.6 0.2 0.46 8.7 0.0 2.3 2 0 0 2 2 2 2 MutL protein Zn_clus PF00172.13 AAS51255.1 - 1.5e-09 37.6 11.3 2.6e-09 36.8 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AAS51255.1 - 8.9e-09 34.4 0.8 1.5e-08 33.6 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fasciclin PF02469.17 AAS51256.2 - 9.3e-12 45.0 0.0 9.7e-05 22.3 0.0 4.4 4 1 0 4 4 4 3 Fasciclin domain Aa_trans PF01490.13 AAS51257.1 - 6.2e-78 262.0 17.1 7.4e-78 261.8 11.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mpp10 PF04006.7 AAS51258.1 - 1.3e-122 410.2 65.0 4.7e-122 408.3 45.0 1.7 1 1 0 1 1 1 1 Mpp10 protein CBF PF03914.12 AAS51259.1 - 2.6e-37 127.8 0.6 2.6e-37 127.8 0.4 2.3 2 0 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 AAS51259.1 - 3.9e-35 120.0 2.0 3.9e-35 120.0 1.4 3.3 3 1 0 3 3 3 1 Nucleolar complex-associated protein Dynamin_N PF00350.18 AAS51259.1 - 2.8e-05 23.9 0.6 2.8e-05 23.9 0.4 2.6 2 0 0 2 2 2 1 Dynamin family Sigma70_ner PF04546.8 AAS51259.1 - 0.41 10.2 19.9 1.8 8.1 6.6 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region RasGAP PF00616.14 AAS51259.1 - 1.1 8.8 12.8 0.42 10.2 2.5 2.8 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Mannosyl_trans PF05007.8 AAS51261.1 - 1e-79 267.8 25.5 1e-79 267.8 17.7 1.6 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 AAS51261.1 - 1.8e-14 53.3 7.0 1.8e-14 53.3 4.9 2.0 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 AAS51261.1 - 2.4e-08 33.8 17.2 2.4e-08 33.8 11.9 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2029) RNase_PH PF01138.16 AAS51262.1 - 2.1e-28 99.2 0.0 2.7e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AAS51262.1 - 1.7e-05 24.6 0.2 7.7e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 FabA PF07977.8 AAS51262.1 - 0.089 12.2 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 FabA-like domain Nramp PF01566.13 AAS51264.1 - 1.1e-91 307.3 13.5 1.4e-91 306.9 9.3 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein HSP70 PF00012.15 AAS51265.1 - 1.8e-266 884.8 11.5 2.1e-266 884.6 8.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AAS51265.1 - 4.8e-19 68.1 1.4 7.4e-18 64.2 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 AAS51265.1 - 0.0011 18.1 7.3 0.06 12.4 0.0 3.5 3 1 0 4 4 4 2 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.15 AAS51265.1 - 0.0083 15.4 0.0 0.12 11.6 0.0 2.4 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.11 AAS51265.1 - 0.031 13.9 0.0 0.23 11.0 0.0 2.3 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 AAS51265.1 - 0.05 13.4 5.3 1 9.2 0.4 3.4 2 2 0 2 2 2 0 Cell division protein FtsA CENP-I PF07778.6 AAS51265.1 - 2.2 6.3 4.8 1.3 7.1 0.1 2.0 2 0 0 2 2 2 0 Mis6 FHA PF00498.21 AAS51266.1 - 2.2e-11 43.6 0.0 3.5e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 FHA domain DEAD PF00270.24 AAS51267.2 - 9.6e-45 152.0 0.1 3e-44 150.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 AAS51267.2 - 3.6e-25 87.2 0.2 7.9e-25 86.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 AAS51267.2 - 1.1e-21 76.4 0.0 2.5e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 AAS51267.2 - 0.025 14.3 0.1 0.38 10.5 0.0 2.7 3 0 0 3 3 3 0 Part of AAA domain CMS1 PF14617.1 AAS51267.2 - 0.091 11.8 0.1 0.091 11.8 0.0 3.4 3 1 1 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit Cyclin_N PF00134.18 AAS51268.2 - 1.6e-15 56.7 9.0 2.1e-15 56.4 3.5 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 AAS51268.2 - 0.02 14.6 0.1 0.094 12.5 0.0 2.1 2 0 0 2 2 2 0 Transcription factor TFIIB repeat PPTA PF01239.17 AAS51269.1 - 1e-37 125.9 9.9 1.5e-10 39.9 0.0 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF3755 PF12579.3 AAS51269.1 - 0.17 11.3 2.1 0.19 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) HORMA PF02301.13 AAS51270.1 - 1.5e-47 161.8 0.1 1.6e-47 161.6 0.1 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 AAS51270.1 - 0.0013 18.2 0.1 0.0031 16.9 0.0 1.5 1 1 0 1 1 1 1 Autophagy-related protein 13 DUF4279 PF14106.1 AAS51270.1 - 0.016 15.1 0.2 0.076 12.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) SspB PF04386.8 AAS51270.1 - 0.029 13.9 0.2 0.073 12.6 0.1 1.7 2 0 0 2 2 2 0 Stringent starvation protein B DUF3440 PF11922.3 AAS51270.1 - 0.085 12.4 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Vps53_N PF04100.7 AAS51271.2 - 7.3e-79 265.3 11.6 1.1e-78 264.7 8.1 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Acetyltransf_11 PF13720.1 AAS51271.2 - 0.094 12.9 0.0 0.34 11.1 0.0 1.9 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DivIVA PF05103.8 AAS51271.2 - 0.21 11.6 3.4 0.36 10.8 1.0 2.4 2 1 0 2 2 2 0 DivIVA protein Cpn60_TCP1 PF00118.19 AAS51272.2 - 1.6e-134 449.2 5.3 1.8e-134 449.0 3.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.15 AAS51272.2 - 0.14 11.5 0.1 0.39 10.1 0.0 1.6 2 0 0 2 2 2 0 EAL domain PUF PF00806.14 AAS51273.2 - 3.1e-27 92.4 7.7 0.00021 20.5 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat DUF3294 PF07957.6 AAS51274.1 - 2.7e-90 301.6 1.9 3e-90 301.5 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) GnsAB PF08178.6 AAS51274.1 - 0.071 12.7 0.1 0.19 11.3 0.1 1.8 1 0 0 1 1 1 0 GnsA/GnsB family HALZ PF02183.13 AAS51274.1 - 1.9 8.2 5.0 1.3 8.7 0.4 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4164 PF13747.1 AAS51274.1 - 9.5 6.4 6.8 19 5.4 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) LTV PF04180.9 AAS51275.1 - 6.7e-110 368.4 26.1 8.2e-110 368.2 18.1 1.0 1 0 0 1 1 1 1 Low temperature viability protein RNA_pol_Rbc25 PF08292.7 AAS51276.1 - 1.1e-45 154.7 0.5 1.5e-45 154.2 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 AAS51276.1 - 1.2e-20 73.3 0.0 2.3e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 AAS51276.1 - 0.00088 19.3 0.0 0.0018 18.3 0.0 1.6 1 1 0 1 1 1 1 S1 RNA binding domain YbaJ PF10757.4 AAS51276.1 - 0.01 15.9 0.1 6.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Biofilm formation regulator YbaJ AAA PF00004.24 AAS51277.1 - 2.3e-40 137.8 0.0 5e-40 136.7 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AAS51277.1 - 6e-06 26.4 0.0 0.001 19.2 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_5 PF07728.9 AAS51277.1 - 2.6e-05 23.9 0.0 0.00012 21.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AAS51277.1 - 8e-05 22.6 0.1 0.00038 20.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 AAS51277.1 - 0.00034 20.5 0.0 0.00071 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 AAS51277.1 - 0.00096 18.1 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 AAS51277.1 - 0.0012 19.6 0.4 0.0041 17.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AAS51277.1 - 0.0053 15.8 0.0 0.0097 14.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AAS51277.1 - 0.0065 16.2 0.2 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 AAS51277.1 - 0.0078 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AAS51277.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 AAS51277.1 - 0.016 14.9 0.8 4.8 6.7 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase AAA_33 PF13671.1 AAS51277.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AAS51277.1 - 0.024 14.9 0.0 0.064 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AAS51277.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 AAS51277.1 - 0.028 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 AAS51277.1 - 0.032 14.4 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 AAS51277.1 - 0.037 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 AAS51277.1 - 0.039 13.1 0.1 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 AAS51277.1 - 0.044 13.8 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 AAS51277.1 - 0.05 12.3 0.0 0.082 11.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 AAS51277.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Aa_trans PF01490.13 AAS51278.2 - 1.1e-84 284.2 30.1 1.4e-84 284.0 20.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FAD_binding_2 PF00890.19 AAS51279.2 - 1.2e-120 403.2 4.4 1.5e-120 402.8 3.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 AAS51279.2 - 1.3e-46 157.6 0.3 1.9e-46 157.1 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 AAS51279.2 - 2.6e-06 26.7 0.2 0.0019 17.3 0.0 3.1 4 0 0 4 4 4 2 Thi4 family GIDA PF01134.17 AAS51279.2 - 1.1e-05 24.5 2.5 0.0025 16.7 1.6 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 AAS51279.2 - 1.2e-05 25.3 1.3 0.00012 21.9 0.6 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AAS51279.2 - 0.00028 19.9 5.1 0.0055 15.6 3.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AAS51279.2 - 0.0046 16.0 0.1 0.011 14.8 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 AAS51279.2 - 0.11 10.9 2.2 0.17 10.3 0.6 2.0 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.1 AAS51279.2 - 0.11 12.5 0.5 1.1 9.2 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Metallophos PF00149.23 AAS51280.1 - 2.5e-07 30.3 0.1 9.9e-07 28.3 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DBR1 PF05011.8 AAS51280.1 - 0.0004 20.2 0.0 0.00072 19.4 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain NAD_binding_1 PF00175.16 AAS51281.1 - 1.8e-28 99.3 0.0 4.5e-28 97.9 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AAS51281.1 - 1.1e-23 83.1 0.0 2.3e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AAS51281.1 - 9e-06 25.6 0.0 0.00038 20.3 0.0 2.3 1 1 0 2 2 2 1 Ferric reductase NAD binding domain Carb_kinase PF01256.12 AAS51282.2 - 2.2e-58 197.4 0.1 6.6e-58 195.8 0.0 1.7 1 1 1 2 2 2 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 AAS51282.2 - 1.9e-06 27.2 0.0 3.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase His_Phos_1 PF00300.17 AAS51283.2 - 1.3e-41 142.3 0.0 1.7e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RabGAP-TBC PF00566.13 AAS51284.1 - 1.1e-23 83.8 0.8 1.6e-23 83.3 0.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LRR_4 PF12799.2 AAS51286.2 - 0.011 15.2 7.4 0.17 11.5 0.0 4.8 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 AAS51286.2 - 0.015 15.4 2.2 4.8 7.8 0.0 5.4 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 AAS51286.2 - 0.051 13.6 10.7 4.3 7.7 0.1 6.1 7 0 0 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.28 AAS51286.2 - 0.1 12.6 4.1 8.1 6.9 0.0 5.4 5 1 1 6 6 6 0 Leucine Rich Repeat Nsp1_C PF05064.8 AAS51287.1 - 3.7e-38 129.7 4.8 3.7e-38 129.7 3.3 2.1 1 1 1 2 2 2 1 Nsp1-like C-terminal region Rsd_AlgQ PF04353.8 AAS51287.1 - 0.0092 15.7 1.0 0.0092 15.7 0.7 2.0 1 1 2 3 3 3 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Caudo_TAP PF02413.12 AAS51287.1 - 0.014 15.5 1.3 0.048 13.8 0.9 2.0 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein Nucleoporin_FG PF13634.1 AAS51287.1 - 0.016 15.4 32.4 0.016 15.4 22.4 5.8 2 1 4 6 6 6 0 Nucleoporin FG repeat region Baculo_p24 PF05073.7 AAS51287.1 - 0.03 13.8 4.7 0.05 13.1 3.3 1.4 1 0 0 1 1 1 0 Baculovirus P24 capsid protein RED_C PF07807.6 AAS51287.1 - 0.054 13.6 5.5 14 5.9 0.0 5.4 5 1 1 6 6 6 0 RED-like protein C-terminal region DUF3168 PF11367.3 AAS51287.1 - 0.087 12.9 0.2 64 3.7 0.0 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3168) SHIPPO-rpt PF07004.7 AAS51287.1 - 0.089 13.7 52.6 11 7.1 0.2 12.5 8 3 2 10 10 10 0 Sperm-tail PG-rich repeat DNA_primase_lrg PF04104.9 AAS51287.1 - 0.18 11.0 2.1 0.25 10.5 0.8 1.6 1 1 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit Muted PF14942.1 AAS51287.1 - 0.47 10.3 7.0 0.7 9.7 4.2 1.7 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF3414 PF11894.3 AAS51288.2 - 0 1612.4 53.7 0 1612.3 37.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) SRPRB PF09439.5 AAS51289.1 - 1.1e-72 243.1 0.0 1.3e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AAS51289.1 - 3.8e-08 33.2 0.0 6.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AAS51289.1 - 9.6e-08 31.6 0.1 4.5e-07 29.4 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 AAS51289.1 - 1.2e-07 31.1 0.0 1.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AAS51289.1 - 4.3e-06 26.0 0.0 5.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_23 PF13476.1 AAS51289.1 - 0.0006 20.1 1.5 0.0009 19.6 1.1 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AAS51289.1 - 0.0021 17.2 0.1 0.0035 16.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 AAS51289.1 - 0.0034 17.8 0.0 0.0077 16.7 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 AAS51289.1 - 0.0037 17.2 0.7 0.026 14.5 0.3 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 AAS51289.1 - 0.0056 16.9 0.2 0.01 16.1 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 AAS51289.1 - 0.012 15.0 0.1 0.022 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain PsaM PF07465.8 AAS51289.1 - 0.026 14.1 1.0 0.053 13.1 0.7 1.6 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) Ras PF00071.17 AAS51289.1 - 0.027 13.8 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Ras family PduV-EutP PF10662.4 AAS51289.1 - 0.027 13.9 0.0 0.56 9.6 0.0 2.6 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 AAS51289.1 - 0.03 13.6 0.0 0.087 12.0 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_17 PF13207.1 AAS51289.1 - 0.039 14.7 0.3 0.11 13.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AAS51289.1 - 0.04 14.0 0.0 0.072 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AAS51289.1 - 0.049 13.1 0.9 0.098 12.2 0.6 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 AAS51289.1 - 0.055 12.9 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 AAS51289.1 - 0.06 12.8 0.5 7.6 5.9 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 AAS51289.1 - 0.066 12.9 0.1 0.066 12.9 0.0 1.9 2 1 0 2 2 1 0 Part of AAA domain Zeta_toxin PF06414.7 AAS51289.1 - 0.093 11.8 0.3 0.16 11.0 0.2 1.3 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 AAS51289.1 - 0.093 12.4 0.1 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase T2SE PF00437.15 AAS51289.1 - 0.1 11.5 0.4 0.2 10.5 0.3 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 AAS51289.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AAS51289.1 - 0.11 12.8 0.2 0.19 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain Rsm22 PF09243.5 AAS51290.1 - 5.7e-35 120.6 0.9 6.9e-13 48.2 0.1 4.3 3 1 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 AAS51290.1 - 0.0002 21.0 0.0 0.00058 19.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS51290.1 - 0.015 15.8 0.0 0.09 13.3 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Ribosomal_S27e PF01667.12 AAS51291.2 - 2.1e-30 103.9 2.7 2.9e-30 103.5 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 AAS51291.2 - 2.7e-05 23.9 0.7 3.3e-05 23.6 0.5 1.1 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 AAS51291.2 - 0.05 12.9 3.8 0.074 12.3 2.6 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 AAS51291.2 - 0.13 11.9 1.3 6.2 6.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AAS51291.2 - 0.14 11.8 1.3 6.3 6.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Ras PF00071.17 AAS51292.1 - 5.9e-20 71.2 0.0 1.1e-16 60.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 AAS51292.1 - 3.7e-07 30.6 0.0 1e-05 26.0 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 AAS51292.1 - 2.8e-05 23.6 0.0 0.00014 21.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 AAS51292.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AAS51292.1 - 0.071 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain IRF-3 PF10401.4 AAS51292.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Interferon-regulatory factor 3 AAA_16 PF13191.1 AAS51292.1 - 0.11 12.4 1.9 0.3 11.0 1.3 2.0 1 1 0 1 1 1 0 AAA ATPase domain F-box-like PF12937.2 AAS51293.1 - 0.00027 20.5 0.0 0.00072 19.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 AAS51293.1 - 0.0011 18.4 1.4 6.4 6.5 0.0 4.2 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AAS51293.1 - 0.0029 17.3 2.5 0.23 11.2 0.1 4.1 5 0 0 5 5 5 1 Leucine rich repeat F-box PF00646.28 AAS51293.1 - 0.0031 17.1 0.0 0.012 15.3 0.0 2.0 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 AAS51293.1 - 0.042 13.8 0.0 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 PRANC domain Myosin_head PF00063.16 AAS51294.2 - 1.5e-243 809.9 14.0 1.5e-243 809.9 9.7 4.4 3 3 1 4 4 4 1 Myosin head (motor domain) Myosin_N PF02736.14 AAS51294.2 - 0.0038 16.8 0.2 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.14 AAS51294.2 - 0.0066 14.2 189.7 0.0083 13.9 28.8 3.7 1 1 1 3 3 3 2 Myosin tail Reo_sigmaC PF04582.7 AAS51294.2 - 0.022 13.9 55.9 0.011 14.9 5.3 6.0 2 2 3 6 6 6 0 Reovirus sigma C capsid protein AAA_19 PF13245.1 AAS51294.2 - 0.33 10.7 0.0 0.95 9.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Peptidase_M16_C PF05193.16 AAS51295.1 - 2.1e-44 151.4 0.0 1.7e-43 148.4 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AAS51295.1 - 3.5e-33 114.4 0.4 1.6e-32 112.3 0.1 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) GHMP_kinases_N PF00288.21 AAS51296.2 - 4.3e-12 45.9 0.0 7.8e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AAS51296.2 - 0.0029 17.7 0.0 0.0067 16.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal ATP-synt_C PF00137.16 AAS51297.1 - 3.5e-28 97.2 29.7 4.9e-18 64.8 6.3 2.4 2 0 0 2 2 2 2 ATP synthase subunit C PC_rep PF01851.17 AAS51298.1 - 3e-26 90.1 12.6 2.6e-07 30.4 0.3 8.3 8 0 0 8 8 8 6 Proteasome/cyclosome repeat Daxx PF03344.10 AAS51298.1 - 0.68 8.3 18.7 1.4 7.3 13.0 1.4 1 0 0 1 1 1 0 Daxx Family DPPIV_N PF00930.16 AAS51299.2 - 3.2e-106 354.9 6.2 4.4e-106 354.4 4.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 AAS51299.2 - 9.7e-52 175.2 0.4 1.7e-51 174.4 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AAS51299.2 - 1.9e-09 37.4 0.1 6.3e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AAS51299.2 - 0.00014 21.8 0.1 0.00077 19.3 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AAS51299.2 - 0.027 14.0 0.0 0.089 12.3 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 AAS51299.2 - 0.16 11.4 0.0 20 4.5 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PX PF00787.19 AAS51300.1 - 2.9e-25 88.2 0.1 9.2e-25 86.6 0.1 1.9 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 AAS51300.1 - 8.5e-07 28.4 16.5 3e-05 23.4 4.8 3.0 3 1 0 3 3 3 2 Vps5 C terminal like Reo_sigmaC PF04582.7 AAS51300.1 - 0.025 13.7 4.1 3.3 6.8 0.0 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 AAS51300.1 - 0.046 13.5 0.0 0.046 13.5 0.0 2.9 2 2 0 2 2 2 0 Tropomyosin like FlaC_arch PF05377.6 AAS51300.1 - 0.048 13.5 6.5 0.83 9.5 0.4 4.0 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) APC2 PF08672.6 AAS51300.1 - 0.051 13.8 0.7 9.7 6.5 0.1 3.1 3 0 0 3 3 2 0 Anaphase promoting complex (APC) subunit 2 NPV_P10 PF05531.7 AAS51300.1 - 0.081 13.1 2.7 3.8 7.8 0.1 3.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DASH_Dam1 PF08653.5 AAS51300.1 - 0.35 10.6 4.8 2.2 8.1 0.0 4.1 5 1 0 5 5 4 0 DASH complex subunit Dam1 HrpB7 PF09486.5 AAS51300.1 - 0.39 10.6 5.6 10 5.9 2.3 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF848 PF05852.6 AAS51300.1 - 0.43 10.4 15.9 0.037 13.8 2.6 3.1 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Vps51 PF08700.6 AAS51300.1 - 0.54 10.1 6.3 3.8 7.4 0.1 4.3 5 0 0 5 5 5 0 Vps51/Vps67 BAR PF03114.13 AAS51300.1 - 1.7 8.0 18.8 11 5.4 11.5 2.8 1 1 1 2 2 2 0 BAR domain DUF1664 PF07889.7 AAS51300.1 - 1.9 8.2 8.3 6.2 6.6 0.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.16 AAS51300.1 - 3 7.8 7.9 18 5.3 2.6 3.4 3 0 0 3 3 3 0 bZIP transcription factor Vac_Fusion PF02346.11 AAS51300.1 - 3.6 7.0 6.0 6.6 6.2 0.0 3.9 4 0 0 4 4 4 0 Chordopoxvirus fusion protein Atg14 PF10186.4 AAS51300.1 - 5.9 5.7 11.5 2.1 7.1 3.9 2.4 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ArdA PF07275.6 AAS51300.1 - 6.5 6.9 14.3 6.1 7.0 1.7 3.3 1 1 0 2 2 2 0 Antirestriction protein (ArdA) dCMP_cyt_deam_1 PF00383.17 AAS51301.1 - 1.7e-21 75.7 0.2 2.4e-21 75.3 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.1 AAS51301.1 - 0.003 17.1 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.6 AAS51301.1 - 0.0063 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.1 AAS51301.1 - 0.0097 15.7 1.1 0.026 14.3 0.1 2.1 2 1 0 2 2 2 1 Bd3614-like deaminase FSH1 PF03959.8 AAS51302.1 - 5.3e-57 192.6 0.0 5.9e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 AAS51302.1 - 6.8e-06 25.8 0.4 1.1e-05 25.2 0.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AAS51302.1 - 7.3e-06 26.0 5.8 0.00099 19.0 4.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AAS51302.1 - 0.0079 15.6 0.3 2.8 7.3 0.2 2.8 3 1 0 3 3 3 2 Phospholipase/Carboxylesterase PE-PPE PF08237.6 AAS51302.1 - 0.048 13.0 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain PAP_central PF04928.12 AAS51302.1 - 0.071 11.9 0.0 0.094 11.5 0.0 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain DEAD PF00270.24 AAS51304.2 - 1.1e-35 122.6 0.4 1.9e-34 118.6 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS51304.2 - 1.2e-24 85.8 0.1 2.5e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS51304.2 - 0.00025 20.9 0.0 0.00065 19.5 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 AAS51304.2 - 0.0043 17.0 0.0 0.05 13.5 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain CMS1 PF14617.1 AAS51304.2 - 0.032 13.2 0.4 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Pmp3 PF01679.12 AAS51305.1 - 1.9e-19 69.1 8.4 2e-19 69.0 5.8 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF3099 PF11298.3 AAS51305.1 - 0.13 11.9 0.5 0.13 11.9 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) BTP PF05232.7 AAS51305.1 - 0.28 10.9 3.2 0.34 10.6 2.2 1.1 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family DUF2304 PF10066.4 AAS51305.1 - 0.36 10.7 3.5 0.38 10.6 2.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) NdhL PF10716.4 AAS51305.1 - 1.3 8.8 5.3 1.7 8.5 3.7 1.3 1 1 0 1 1 1 0 NADH dehydrogenase transmembrane subunit CoxIIa PF08113.6 AAS51305.1 - 7.2 6.4 7.0 11 5.8 0.1 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family TOMM6 PF15184.1 AAS51306.1 - 0.017 14.4 0.1 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog US22 PF02393.11 AAS51307.1 - 0.15 12.0 5.5 0.26 11.3 3.8 1.3 1 0 0 1 1 1 0 US22 like BTB_2 PF02214.17 AAS51308.1 - 0.039 14.1 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 BTB/POZ domain CUE PF02845.11 AAS51309.1 - 1.3e-08 34.1 0.0 2.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain TBCA PF02970.11 AAS51309.1 - 0.04 13.9 0.2 0.04 13.9 0.2 2.4 2 0 0 2 2 2 0 Tubulin binding cofactor A OmpH PF03938.9 AAS51309.1 - 0.65 9.9 11.8 1.7 8.5 8.2 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2756 PF10956.3 AAS51309.1 - 0.76 10.0 4.1 0.76 10.0 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) DUF1525 PF07511.6 AAS51309.1 - 1.2 9.1 6.1 0.24 11.3 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) Mnd1 PF03962.10 AAS51309.1 - 1.4 8.5 5.9 0.16 11.5 1.1 1.6 2 0 0 2 2 2 0 Mnd1 family Lactamase_B PF00753.22 AAS51310.1 - 2.6e-24 85.9 0.3 3.6e-24 85.4 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AAS51310.1 - 5.6e-06 26.0 0.1 1.1e-05 25.0 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AAS51310.1 - 0.075 12.7 0.3 0.18 11.4 0.2 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain WD40 PF00400.27 AAS51311.1 - 6.5e-06 25.8 2.9 5.4 7.0 0.0 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat PQQ_2 PF13360.1 AAS51311.1 - 0.029 13.8 0.0 6.5 6.1 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain E1-E2_ATPase PF00122.15 AAS51312.2 - 9.4e-46 155.6 0.0 1.5e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AAS51312.2 - 2.9e-33 116.0 0.0 1.4e-32 113.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AAS51312.2 - 1.1e-15 58.3 0.0 2.2e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 AAS51312.2 - 1.1e-13 51.0 3.5 2.1e-13 50.1 2.4 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 AAS51312.2 - 0.0022 17.6 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase CK_II_beta PF01214.13 AAS51313.1 - 2.8e-71 238.8 0.1 3.4e-71 238.5 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Hira PF07569.6 AAS51314.2 - 2.1e-86 288.6 0.1 2e-85 285.4 0.0 2.2 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 AAS51314.2 - 0.018 14.9 0.3 1.8 8.5 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat tRNA-synt_1b PF00579.20 AAS51315.1 - 1.3e-70 237.8 0.0 1.6e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NCD1 PF04904.8 AAS51315.1 - 0.075 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) FAD_binding_6 PF00970.19 AAS51316.2 - 6.5e-06 26.1 0.0 3.7e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain WD40 PF00400.27 AAS51317.1 - 1.7e-52 173.5 31.6 4.6e-12 45.3 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 AAS51317.1 - 0.00078 19.2 0.2 0.0034 17.1 0.0 2.1 2 2 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 AAS51317.1 - 0.007 14.2 1.9 0.013 13.4 1.3 1.4 1 0 0 1 1 1 1 IKI3 family Coatomer_WDAD PF04053.9 AAS51317.1 - 0.044 12.5 6.0 0.065 12.0 0.4 2.7 2 1 1 3 3 3 0 Coatomer WD associated region TFIIIC_delta PF12657.2 AAS51317.1 - 0.4 10.3 7.0 6.3 6.4 0.1 3.7 1 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term SNARE PF05739.14 AAS51318.1 - 9.5e-19 66.8 1.8 2.3e-18 65.6 1.3 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.1 AAS51318.1 - 2.7e-16 59.4 1.5 2.7e-16 59.4 1.0 2.4 2 0 0 2 2 2 1 Syntaxin-like protein Baculo_PEP_C PF04513.7 AAS51318.1 - 0.001 18.8 3.1 0.35 10.6 0.2 2.5 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 AAS51318.1 - 4.6 7.3 11.4 1.2 9.3 4.1 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family ATP-synt_S1 PF05827.7 AAS51319.2 - 4.9e-62 209.7 0.0 5.8e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Parecho_VpG PF06344.6 AAS51319.2 - 3.9 7.5 5.3 0.5 10.3 0.8 1.7 2 0 0 2 2 2 0 Parechovirus Genome-linked protein PPTA PF01239.17 AAS51320.1 - 2.6e-31 105.6 15.4 3.7e-07 29.1 0.2 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Linker_histone PF00538.14 AAS51321.1 - 1.1e-20 73.5 0.1 1.1e-20 73.5 0.0 1.8 2 0 0 2 2 2 1 linker histone H1 and H5 family DUF572 PF04502.8 AAS51321.1 - 5.7 6.0 9.0 7.3 5.7 6.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) TRF PF08558.5 AAS51322.1 - 2.8e-78 262.5 0.1 4.1e-78 262.0 0.1 1.1 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 AAS51322.1 - 5e-07 29.6 0.3 1.2e-06 28.5 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AAS51322.1 - 0.00028 20.9 0.1 0.00061 19.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.27 AAS51323.1 - 3.3e-43 144.0 21.3 1.9e-08 33.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat YEATS PF03366.11 AAS51324.1 - 1.3e-20 72.9 0.0 2e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 YEATS family YEATS PF03366.11 AAS51325.1 - 4.4e-25 87.2 0.0 7.1e-25 86.5 0.0 1.3 1 0 0 1 1 1 1 YEATS family YqeY PF09424.5 AAS51326.1 - 4e-23 81.8 0.3 6.3e-23 81.2 0.2 1.3 1 0 0 1 1 1 1 Yqey-like protein Pox_A3L PF05288.6 AAS51326.1 - 0.0044 16.7 0.2 0.0078 15.9 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A3L Protein GRAB PF10375.4 AAS51327.2 - 5.1e-07 29.0 2.1 1.1e-06 28.0 1.4 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Myosin_tail_1 PF01576.14 AAS51327.2 - 0.00019 19.3 62.7 0.0012 16.6 43.5 2.0 1 1 0 1 1 1 1 Myosin tail IncA PF04156.9 AAS51327.2 - 0.00051 19.6 73.6 1.1 8.8 17.7 3.9 1 1 1 2 2 2 1 IncA protein Reo_sigmaC PF04582.7 AAS51327.2 - 0.0038 16.4 17.6 0.13 11.3 2.9 2.4 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Phage_GP20 PF06810.6 AAS51327.2 - 0.0073 15.7 2.2 0.0073 15.7 1.6 4.3 2 1 2 4 4 4 1 Phage minor structural protein GP20 GAS PF13851.1 AAS51327.2 - 0.021 14.0 57.8 0.42 9.7 13.1 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 AAS51327.2 - 0.045 12.2 40.6 0.0064 15.0 22.0 2.1 1 1 1 2 2 2 0 AAA domain DUF1664 PF07889.7 AAS51327.2 - 0.58 9.9 26.6 0.12 12.1 2.0 3.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 AAS51327.2 - 0.8 9.8 33.9 0.26 11.4 10.6 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Filament PF00038.16 AAS51327.2 - 1.9 7.8 58.8 1 8.7 16.6 4.1 1 1 3 4 4 4 0 Intermediate filament protein ADIP PF11559.3 AAS51327.2 - 4.1 7.2 63.7 0.045 13.6 9.0 4.8 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 AAS51327.2 - 8.2 4.9 50.0 0.67 8.5 13.8 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein RFC1 PF08519.7 AAS51328.2 - 1.1e-57 194.1 0.1 3.7e-57 192.4 0.0 2.0 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.24 AAS51328.2 - 2e-13 50.6 0.0 5.3e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 AAS51328.2 - 3.6e-10 39.8 0.0 8.3e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.10 AAS51328.2 - 2.5e-06 26.4 0.0 0.0013 17.5 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AAS51328.2 - 3.5e-06 27.1 0.0 1.1e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AAS51328.2 - 4.7e-06 27.4 0.1 6.8e-05 23.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 AAS51328.2 - 3.1e-05 23.1 0.0 5.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AAS51328.2 - 0.00033 20.6 0.3 0.02 14.8 0.0 3.5 3 1 1 4 4 4 1 AAA ATPase domain AAA_33 PF13671.1 AAS51328.2 - 0.00091 19.1 0.1 0.0031 17.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AAS51328.2 - 0.0016 18.3 0.0 0.0055 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AAS51328.2 - 0.0038 17.5 0.1 0.017 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain PTCB-BRCT PF12738.2 AAS51328.2 - 0.004 16.9 0.1 0.026 14.3 0.0 2.4 2 0 0 2 2 2 1 twin BRCT domain RNA_helicase PF00910.17 AAS51328.2 - 0.011 15.9 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 AAS51328.2 - 0.014 15.1 0.1 0.15 11.8 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 AAS51328.2 - 0.03 13.9 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AAS51328.2 - 0.032 14.2 0.2 0.09 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 AAS51328.2 - 0.055 13.1 0.0 0.44 10.1 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_5 PF07728.9 AAS51328.2 - 0.07 12.8 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 AAS51328.2 - 0.11 12.2 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 NTPase DPPIV_N PF00930.16 AAS51329.2 - 9.7e-94 313.8 0.0 1.4e-93 313.2 0.0 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 AAS51329.2 - 2.5e-47 160.8 0.4 4.3e-47 160.0 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AAS51329.2 - 2.5e-07 30.5 0.0 7.7e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 AAS51329.2 - 2.6e-05 22.6 0.0 0.0027 16.0 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.15 AAS51329.2 - 0.00016 21.1 0.0 0.00036 20.0 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 AAS51329.2 - 0.009 15.9 0.0 0.11 12.3 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L18p PF00861.17 AAS51330.1 - 5.8e-46 155.5 1.7 1.7e-45 154.0 0.0 2.3 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 AAS51330.1 - 2.3e-34 117.8 2.7 2.3e-34 117.8 1.9 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 AAS51330.1 - 0.088 12.8 0.2 0.9 9.6 0.0 2.5 3 0 0 3 3 3 0 Threonine synthase N terminus CtaG_Cox11 PF04442.9 AAS51332.1 - 1.3e-58 197.1 0.0 1.7e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Zn_clus PF00172.13 AAS51333.2 - 0.00043 20.1 12.6 0.0011 18.8 8.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl_transf_1 PF00698.16 AAS51334.1 - 0.00011 21.6 3.7 0.00016 21.1 2.6 1.4 1 1 0 1 1 1 1 Acyl transferase domain Mito_carr PF00153.22 AAS51335.2 - 2.1e-68 226.0 1.0 4.7e-26 90.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2407_C PF13373.1 AAS51336.1 - 8.9e-40 135.8 0.3 1.4e-39 135.1 0.2 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 AAS51336.1 - 2.2e-16 59.8 0.0 4.1e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2453 PF10507.4 AAS51336.1 - 0.033 13.9 0.3 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2453) SICA_alpha PF12887.2 AAS51336.1 - 0.045 13.5 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 SICA extracellular alpha domain MerR-DNA-bind PF09278.6 AAS51336.1 - 0.41 11.0 2.4 30 5.1 0.2 2.8 3 1 0 3 3 3 0 MerR, DNA binding RNA_pol_Rpb8 PF03870.10 AAS51337.1 - 6.3e-45 152.7 0.0 7e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 NifU_N PF01592.11 AAS51338.1 - 3.9e-54 181.9 0.1 4.6e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DUF1691 PF07950.6 AAS51340.1 - 1.3e-38 131.3 9.9 2.6e-19 69.1 0.2 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Frizzled PF01534.12 AAS51340.1 - 0.0056 15.5 0.1 0.013 14.2 0.1 1.6 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region MPC PF03650.8 AAS51340.1 - 0.006 16.5 0.1 0.75 9.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0041) PHD PF00628.24 AAS51341.2 - 4.9e-12 45.3 4.2 4.9e-12 45.3 2.9 1.9 2 0 0 2 2 2 1 PHD-finger zf-BED PF02892.10 AAS51341.2 - 0.75 9.6 5.3 3.3 7.5 0.5 2.6 2 0 0 2 2 2 0 BED zinc finger zf-HC5HC2H PF13771.1 AAS51341.2 - 1.5 8.9 7.8 0.12 12.5 1.3 2.2 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RING_2 PF13639.1 AAS51341.2 - 5.7 6.8 13.5 0.045 13.5 3.5 1.9 2 0 0 2 2 2 0 Ring finger domain WD40 PF00400.27 AAS51342.2 - 1.1e-09 37.7 5.8 0.00032 20.4 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 AAS51342.2 - 0.046 13.6 0.1 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Pkinase PF00069.20 AAS51343.1 - 3.6e-67 226.2 0.0 4.7e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51343.1 - 1.5e-38 132.3 0.0 2.3e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS51343.1 - 8.4e-09 34.7 0.0 1.5e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AAS51343.1 - 0.0073 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AAS51343.1 - 0.016 14.9 0.0 0.11 12.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AAS51343.1 - 0.077 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 GrpE PF01025.14 AAS51344.1 - 7e-49 165.5 0.0 8.4e-49 165.3 0.0 1.0 1 0 0 1 1 1 1 GrpE DUF4515 PF14988.1 AAS51344.1 - 0.053 13.1 0.1 0.075 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Sugarporin_N PF11471.3 AAS51344.1 - 0.2 11.3 0.7 0.37 10.4 0.5 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Pkinase PF00069.20 AAS51345.2 - 1.2e-61 208.1 0.0 1.8e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51345.2 - 3.4e-36 124.6 0.0 5.1e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS51345.2 - 5.3e-06 25.5 0.0 8.9e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AAS51345.2 - 0.022 14.4 0.1 0.27 10.9 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L35Ae PF01247.13 AAS51346.1 - 1.4e-42 143.4 0.8 1.5e-42 143.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 AAS51346.1 - 0.00015 21.5 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Pyr_redox_3 PF13738.1 AAS51348.2 - 7.6e-24 84.9 0.0 1.5e-23 83.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AAS51348.2 - 6.3e-19 67.5 0.0 1.3e-11 43.4 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 AAS51348.2 - 1.7e-11 43.6 0.0 3.6e-08 32.7 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 AAS51348.2 - 3.6e-08 33.5 0.0 9.5e-08 32.1 0.0 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AAS51348.2 - 1.5e-05 24.9 1.7 6.5e-05 22.8 0.0 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 AAS51348.2 - 0.00012 21.2 0.1 0.00022 20.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.14 AAS51348.2 - 0.00041 19.5 0.1 0.018 14.1 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 AAS51348.2 - 0.00049 20.4 0.7 0.59 10.5 0.1 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 AAS51348.2 - 0.00062 19.9 0.0 0.19 11.9 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 AAS51348.2 - 0.006 15.4 0.5 0.023 13.5 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 AAS51348.2 - 0.0076 16.3 0.0 5.4 7.1 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 AAS51348.2 - 0.054 12.4 1.8 0.12 11.2 0.1 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.9 AAS51348.2 - 0.083 11.3 0.1 0.13 10.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 AAS51348.2 - 0.11 12.2 0.2 16 5.2 0.1 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding chaperone_DMP PF10448.4 AAS51349.1 - 4.9e-23 81.6 0.0 5.4e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 20S proteasome chaperone RepC PF06504.6 AAS51349.1 - 0.1 11.5 0.0 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 Replication protein C (RepC) DHFR_1 PF00186.14 AAS51350.1 - 1.2e-29 103.0 0.0 1.7e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase Oxysterol_BP PF01237.13 AAS51351.1 - 3.1e-92 308.7 0.0 3.6e-92 308.5 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Nop53 PF07767.6 AAS51352.1 - 2.7e-108 362.4 42.3 3.1e-108 362.2 29.4 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) ABC_membrane_2 PF06472.10 AAS51354.2 - 2.3e-88 296.0 8.3 3.7e-88 295.3 5.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 AAS51354.2 - 5.1e-14 52.7 0.0 1.3e-13 51.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.14 AAS51354.2 - 0.0034 16.6 0.2 0.27 10.4 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AAS51354.2 - 0.0043 17.0 0.3 0.072 13.0 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AAS51354.2 - 0.12 11.8 0.2 0.39 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain ACPS PF01648.15 AAS51355.2 - 1.2e-16 60.5 0.0 1.6e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Methyltransf_23 PF13489.1 AAS51356.2 - 1.2e-17 64.1 0.0 2.3e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AAS51356.2 - 9.5e-17 61.2 6.2 8.5e-16 58.2 0.0 3.4 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.7 AAS51356.2 - 1.3e-10 41.5 0.0 1.2e-09 38.5 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS51356.2 - 4.4e-10 39.3 0.0 1.8e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AAS51356.2 - 6.9e-10 39.1 0.0 2.5e-09 37.4 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS51356.2 - 2.5e-08 34.5 0.0 1.4e-07 32.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AAS51356.2 - 3e-06 27.2 0.0 9.7e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 AAS51356.2 - 0.00015 20.8 0.0 0.075 11.9 0.0 2.3 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family MTS PF05175.9 AAS51356.2 - 0.0042 16.4 0.1 0.032 13.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain TPMT PF05724.6 AAS51356.2 - 0.0049 16.3 0.1 0.047 13.1 0.0 2.5 2 1 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) DUF3419 PF11899.3 AAS51356.2 - 0.0085 14.8 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.1 AAS51356.2 - 0.013 16.2 0.0 0.056 14.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF572 PF04502.8 AAS51356.2 - 0.098 11.8 28.8 0.17 11.1 19.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Methyltransf_32 PF13679.1 AAS51356.2 - 0.26 10.9 2.5 0.38 10.4 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain APG5 PF04106.7 AAS51357.2 - 8.3e-47 159.2 0.0 1e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 SGT1 PF07093.6 AAS51358.1 - 2.9e-33 115.1 0.6 3.3e-27 95.1 0.0 2.1 2 0 0 2 2 2 2 SGT1 protein Pkinase PF00069.20 AAS51359.1 - 3.5e-65 219.7 0.0 5.5e-65 219.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51359.1 - 3e-35 121.5 0.0 4.8e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS51359.1 - 9.8e-10 37.8 0.2 2.6e-08 33.1 0.0 2.7 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 AAS51359.1 - 0.019 14.0 0.0 0.067 12.2 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AAS51359.1 - 0.024 14.3 0.0 0.069 12.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Mur_ligase_M PF08245.7 AAS51360.2 - 3.7e-05 23.8 2.4 0.0031 17.5 1.7 3.0 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 AAS51360.2 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain AAA_19 PF13245.1 AAS51360.2 - 0.024 14.3 7.5 0.093 12.4 0.0 3.6 3 1 0 3 3 3 0 Part of AAA domain RRM_5 PF13893.1 AAS51361.1 - 1.2e-05 25.0 0.0 0.00084 19.1 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AAS51361.1 - 0.0079 15.8 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruD PF01142.13 AAS51362.1 - 9.9e-67 225.2 0.5 1.8e-60 204.6 0.0 4.5 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) YhzD PF14120.1 AAS51362.1 - 0.04 13.8 0.2 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 YhzD-like protein WD40 PF00400.27 AAS51363.2 - 5.7e-46 152.8 21.6 1.5e-10 40.5 2.2 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AAS51363.2 - 0.0012 17.6 0.1 0.47 9.1 0.0 3.4 1 1 2 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 AAS51363.2 - 0.048 13.1 0.1 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain Nup160 PF11715.3 AAS51363.2 - 0.061 11.4 9.2 1.9 6.5 0.6 4.0 2 1 2 4 4 4 0 Nucleoporin Nup120/160 MOZ_SAS PF01853.13 AAS51364.2 - 4.5e-89 296.6 0.6 6.5e-89 296.1 0.4 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 AAS51364.2 - 5.3e-23 80.4 0.1 1.1e-22 79.4 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 AAS51364.2 - 0.03 14.3 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family PTPA PF03095.10 AAS51365.1 - 1.7e-115 385.3 0.0 1.9e-115 385.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein UDPG_MGDP_dh_C PF03720.10 AAS51365.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DAGAT PF03982.8 AAS51366.1 - 1.7e-82 276.4 2.6 1.2e-75 253.9 0.0 2.1 1 1 1 2 2 2 2 Diacylglycerol acyltransferase LicD PF04991.8 AAS51367.2 - 8.1e-31 107.7 2.1 1.7e-29 103.4 1.5 2.1 1 1 0 1 1 1 1 LicD family Pkinase PF00069.20 AAS51368.2 - 5.5e-77 258.4 0.0 9.5e-77 257.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51368.2 - 1.2e-37 129.3 0.0 1.9e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 AAS51368.2 - 3.3e-25 87.9 0.9 3.7e-14 52.5 0.1 2.7 2 0 0 2 2 2 2 FHA domain Kinase-like PF14531.1 AAS51368.2 - 5.8e-08 32.0 0.0 1.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AAS51368.2 - 3.5e-06 26.9 0.0 0.0051 16.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 AAS51368.2 - 1.3e-05 24.3 0.0 2.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AAS51368.2 - 0.0016 17.8 0.0 0.0033 16.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Asp PF00026.18 AAS51369.1 - 1.2e-77 261.3 0.3 1.4e-77 261.0 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AAS51369.1 - 1.5e-07 31.5 0.0 6e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 AAS51369.1 - 3.9e-06 26.5 0.0 0.00019 21.0 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 AAS51369.1 - 3.8e-05 24.0 0.2 0.53 10.8 0.0 3.7 2 1 1 3 3 3 2 Aspartyl protease Asp PF00026.18 AAS51370.1 - 2.3e-98 329.3 0.0 2.9e-98 329.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AAS51370.1 - 4.8e-10 39.6 0.0 1.5e-09 37.9 0.0 1.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 AAS51370.1 - 6.5e-07 29.0 0.0 9.2e-06 25.2 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 AAS51370.1 - 0.00014 22.2 0.0 0.0053 17.2 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease Kinesin PF00225.18 AAS51371.1 - 6.3e-103 343.9 0.1 6.3e-103 343.9 0.0 1.4 2 0 0 2 2 2 1 Kinesin motor domain Med9 PF07544.8 AAS51371.1 - 1.5 8.6 10.2 0.48 10.2 0.7 3.3 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF641 PF04859.7 AAS51371.1 - 1.5 8.5 10.9 1.8 8.2 0.3 3.4 2 1 0 3 3 3 0 Plant protein of unknown function (DUF641) Methyltransf_15 PF09445.5 AAS51373.1 - 6.1e-63 211.2 0.0 8.2e-63 210.8 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 AAS51373.1 - 5.9e-11 42.4 0.2 1.7e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 AAS51373.1 - 1.5e-07 31.1 0.0 2.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 AAS51373.1 - 2.2e-05 24.7 0.0 5.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS51373.1 - 8.1e-05 23.1 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS51373.1 - 0.00055 19.5 0.0 0.00081 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AAS51373.1 - 0.0044 16.1 0.0 0.007 15.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase N6_Mtase PF02384.11 AAS51373.1 - 0.019 14.0 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase NLE PF08154.7 AAS51373.1 - 0.081 12.9 0.8 8.6 6.4 0.1 2.2 1 1 1 2 2 2 0 NLE (NUC135) domain Methyltransf_23 PF13489.1 AAS51373.1 - 0.11 12.1 0.1 0.28 10.8 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.10 AAS51373.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF2718 PF10918.3 AAS51374.1 - 0.091 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) Abhydrolase_6 PF12697.2 AAS51375.1 - 2.4e-13 50.5 0.0 4.2e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AAS51375.1 - 9.6e-12 44.9 0.0 2.3e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AAS51375.1 - 4.2e-06 26.5 0.0 1e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 AAS51375.1 - 0.0081 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Asp PF00026.18 AAS51376.1 - 1.8e-20 73.4 0.0 5.6e-20 71.8 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AAS51376.1 - 0.056 13.4 0.0 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal DUF2613 PF11021.3 AAS51376.1 - 0.073 12.7 0.9 0.17 11.6 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Sec23_trunk PF04811.10 AAS51377.2 - 1.1e-53 182.0 0.0 2.5e-53 180.9 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 AAS51377.2 - 8.8e-20 70.0 0.3 1.7e-19 69.1 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 AAS51377.2 - 2.9e-14 53.3 0.1 5.4e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 AAS51377.2 - 7.2e-13 47.8 4.0 1.3e-12 47.0 2.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 AAS51377.2 - 2.9e-06 26.8 0.0 7.9e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat zf-RING_5 PF14634.1 AAS51377.2 - 0.35 10.6 3.9 1.6 8.5 0.6 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Pal1 PF08316.6 AAS51378.1 - 1.5e-54 184.2 0.9 1.5e-54 184.2 0.6 2.2 3 0 0 3 3 3 1 Pal1 cell morphology protein DUF1777 PF08648.7 AAS51378.1 - 0.00014 21.6 13.9 0.00014 21.6 9.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) DUF2413 PF10310.4 AAS51378.1 - 8 5.1 8.7 14 4.3 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Sod_Fe_C PF02777.13 AAS51379.1 - 3.4e-10 39.7 0.1 0.00084 19.1 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain APG6 PF04111.7 AAS51380.1 - 1.6e-104 349.3 4.5 2.2e-104 348.9 3.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF3024 PF11225.3 AAS51380.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) DUF4337 PF14235.1 AAS51380.1 - 0.052 13.3 2.8 0.19 11.5 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) V_ATPase_I PF01496.14 AAS51380.1 - 0.096 10.5 5.4 0.16 9.7 3.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 AAS51380.1 - 0.22 11.1 15.0 0.12 11.9 9.0 1.6 2 0 0 2 2 2 0 IncA protein DUF603 PF04645.7 AAS51380.1 - 0.88 9.4 9.7 7.1 6.5 4.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF603 AAA_23 PF13476.1 AAS51380.1 - 9.3 6.5 18.6 2.1 8.6 9.6 2.1 2 2 0 2 2 2 0 AAA domain Ribonuc_red_lgC PF02867.10 AAS51381.1 - 7.4e-207 688.1 0.0 1.4e-206 687.2 0.0 1.4 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 AAS51381.1 - 1.3e-24 85.7 0.0 3.7e-24 84.3 0.0 1.8 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 AAS51381.1 - 0.022 15.1 0.0 0.065 13.6 0.0 1.8 1 0 0 1 1 1 0 ATP cone domain Ribonuclease_T2 PF00445.13 AAS51382.1 - 3e-32 111.7 0.0 5.6e-32 110.8 0.0 1.4 1 1 1 2 2 2 1 Ribonuclease T2 family Y_phosphatase PF00102.22 AAS51384.2 - 4.1e-58 196.4 0.1 9.8e-58 195.2 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 AAS51384.2 - 0.0026 18.0 0.1 0.01 16.0 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 AAS51384.2 - 0.014 15.4 0.0 0.24 11.4 0.0 2.5 2 0 0 2 2 2 0 Inositol hexakisphosphate DSPc PF00782.15 AAS51384.2 - 0.02 14.4 0.0 0.046 13.2 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain IBN_N PF03810.14 AAS51385.2 - 5.6e-15 55.0 2.7 9.7e-15 54.2 0.5 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 AAS51385.2 - 0.41 11.2 2.1 8 7.0 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat NAPRTase PF04095.11 AAS51386.1 - 1.9e-64 217.2 0.0 2.4e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family WD40 PF00400.27 AAS51388.1 - 8e-05 22.3 11.4 0.0092 15.8 0.2 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Arr-ms PF12120.3 AAS51388.1 - 0.034 14.0 0.0 0.61 10.0 0.0 2.8 3 0 0 3 3 3 0 Rifampin ADP-ribosyl transferase RNA_pol_N PF01194.12 AAS51389.1 - 2.5e-29 101.0 0.5 2.9e-29 100.8 0.4 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 AAS51389.1 - 0.039 14.0 0.2 0.049 13.7 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) YhfH PF14149.1 AAS51389.1 - 0.077 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 YhfH-like protein Dynamin_N PF00350.18 AAS51390.2 - 6.9e-43 146.3 0.7 1.8e-42 145.0 0.0 2.2 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 AAS51390.2 - 0.00091 18.0 5.7 0.0085 14.9 0.0 3.1 3 0 0 3 3 3 2 Dynamin central region AAA_16 PF13191.1 AAS51390.2 - 0.0022 18.0 0.4 0.033 14.1 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 AAS51390.2 - 0.0025 17.7 0.0 0.012 15.5 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AAS51390.2 - 0.0034 17.8 0.1 0.012 16.0 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 AAS51390.2 - 0.07 12.2 1.3 0.54 9.3 0.1 2.7 3 0 0 3 3 3 0 AIG1 family Ank PF00023.25 AAS51391.1 - 3.8e-16 58.0 0.1 9.3e-07 28.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 AAS51391.1 - 8.5e-12 45.2 0.1 2.9e-11 43.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 AAS51391.1 - 1.9e-11 44.1 0.1 4.3e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 AAS51391.1 - 1.3e-10 41.1 0.2 4.7e-10 39.3 0.1 2.1 1 0 0 1 1 1 1 IPT/TIG domain Ank_3 PF13606.1 AAS51391.1 - 3.4e-10 39.1 0.1 0.00096 19.1 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 AAS51391.1 - 4.8e-09 36.1 0.1 3.1e-05 24.0 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Nodulin-like PF06813.8 AAS51391.1 - 0.14 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Nodulin-like WD40 PF00400.27 AAS51392.2 - 1.6e-33 113.3 2.1 5.9e-08 32.3 0.1 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AAS51392.2 - 4.1e-06 25.8 4.8 1.3 7.6 0.0 4.8 1 1 3 4 4 4 3 Nup133 N terminal like Nup160 PF11715.3 AAS51392.2 - 6.5e-05 21.2 1.1 0.00037 18.7 0.3 2.1 2 1 0 2 2 2 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 AAS51392.2 - 0.0082 15.9 1.6 5.8 6.7 0.0 4.2 2 1 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region NifZ PF04319.8 AAS51392.2 - 0.051 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 NifZ domain AlaDh_PNT_N PF05222.10 AAS51393.1 - 2.1e-32 111.9 0.0 3.4e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 AAS51393.1 - 9.6e-14 51.2 0.0 1.5e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TPR_1 PF00515.23 AAS51394.1 - 1.1e-40 135.6 10.4 1.1e-05 24.7 0.0 10.3 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 AAS51394.1 - 2e-35 117.8 7.3 0.0013 18.4 0.0 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat Apc3 PF12895.2 AAS51394.1 - 2.4e-33 114.1 8.8 1.2e-21 76.6 0.0 5.5 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 AAS51394.1 - 1.6e-32 110.9 7.3 6.2e-08 32.1 0.0 7.3 5 2 2 7 7 7 5 TPR repeat TPR_12 PF13424.1 AAS51394.1 - 2.2e-25 88.3 7.0 1.9e-07 30.9 0.0 7.6 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 AAS51394.1 - 5.6e-22 75.8 10.7 0.00016 21.2 0.1 8.7 10 0 0 10 10 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 AAS51394.1 - 1e-21 77.0 0.5 0.00019 21.7 0.0 7.2 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 AAS51394.1 - 3.9e-21 75.1 0.0 0.00029 21.4 0.0 6.8 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 AAS51394.1 - 6.4e-19 66.5 2.5 0.0097 16.0 0.0 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 AAS51394.1 - 5.6e-18 63.8 0.0 0.043 14.4 0.0 8.3 5 2 4 9 9 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 AAS51394.1 - 1e-12 46.8 7.6 0.0072 16.0 0.0 8.0 10 0 0 10 10 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 AAS51394.1 - 1.5e-12 47.0 4.8 0.89 10.1 0.1 9.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 AAS51394.1 - 3.5e-11 42.6 0.6 0.54 10.2 0.0 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 AAS51394.1 - 6.3e-08 32.0 0.2 0.23 10.5 0.0 4.6 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_3 PF07720.7 AAS51394.1 - 3.5e-07 29.8 4.4 0.1 12.4 0.0 4.9 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 AAS51394.1 - 5.3e-07 29.3 0.0 0.0073 16.1 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.5 AAS51394.1 - 1.5e-05 23.9 1.5 0.027 13.2 0.2 3.2 3 1 1 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.1 AAS51394.1 - 2.3e-05 24.1 6.7 2.3 8.1 0.1 5.7 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat SNAP PF14938.1 AAS51394.1 - 0.016 14.3 4.5 7.4 5.6 0.0 3.9 3 2 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_20 PF14561.1 AAS51394.1 - 0.026 14.6 0.2 14 5.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat SPO22 PF08631.5 AAS51394.1 - 0.053 12.5 1.6 5.1 6.0 0.1 3.1 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_21 PF09976.4 AAS51394.1 - 0.08 12.8 5.3 6.4 6.7 0.0 4.6 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 AAS51394.1 - 0.14 12.6 0.1 77 4.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat SOG2 PF10428.4 AAS51395.1 - 0.89 8.1 4.0 0.99 7.9 2.8 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein ADK PF00406.17 AAS51396.1 - 6.4e-44 149.4 0.0 8.9e-44 148.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 AAS51396.1 - 1.7e-10 41.2 0.0 2.8e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AAS51396.1 - 1.1e-07 31.8 0.0 2.9e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 AAS51396.1 - 9.2e-06 25.1 0.2 0.066 12.5 0.0 2.2 1 1 1 2 2 2 2 Thymidylate kinase AAA_17 PF13207.1 AAS51396.1 - 1e-05 26.3 0.0 1.6e-05 25.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AAS51396.1 - 0.00041 19.5 0.0 0.00074 18.6 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 AAS51396.1 - 0.14 11.9 0.0 0.14 11.9 0.0 2.6 4 0 0 4 4 4 0 Part of AAA domain adh_short PF00106.20 AAS51397.1 - 4.5e-30 104.7 3.9 6.6e-30 104.2 2.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AAS51397.1 - 4.3e-17 62.6 0.1 5.2e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AAS51397.1 - 2.1e-09 37.3 5.2 3.8e-09 36.4 3.5 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 AAS51397.1 - 5.3e-05 22.7 1.0 0.00018 21.0 0.7 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AAS51397.1 - 0.0019 18.2 1.2 0.0034 17.3 0.7 1.5 1 1 0 1 1 1 1 NADH(P)-binding PP2C_2 PF13672.1 AAS51397.1 - 0.0088 15.4 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Methyltransf_18 PF12847.2 AAS51397.1 - 0.024 15.2 0.1 0.055 14.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 AAS51397.1 - 0.034 13.0 0.2 0.062 12.1 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein TPR_11 PF13414.1 AAS51399.1 - 1.6e-08 34.0 1.3 1.1e-07 31.3 0.6 2.5 2 1 1 3 3 3 1 TPR repeat TPR_2 PF07719.12 AAS51399.1 - 1.4e-07 30.8 6.5 1.7e-07 30.6 0.1 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 AAS51399.1 - 1.9e-07 30.3 0.3 5e-06 25.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 AAS51399.1 - 4.9e-05 22.8 0.1 4.9e-05 22.8 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 AAS51399.1 - 0.00018 22.1 2.8 0.001 19.6 0.4 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 AAS51399.1 - 0.0023 17.7 1.5 0.0054 16.5 0.1 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 AAS51399.1 - 0.007 16.4 0.7 1.4 9.3 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 AAS51399.1 - 0.0077 16.6 0.1 0.27 11.7 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 AAS51399.1 - 0.0079 16.7 3.3 0.024 15.2 0.1 3.2 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 AAS51399.1 - 0.0085 16.0 0.4 0.074 12.9 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 AAS51399.1 - 0.012 15.9 2.3 0.082 13.2 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.3 AAS51399.1 - 0.031 13.0 0.2 0.21 10.3 0.0 2.1 1 1 0 2 2 2 0 NMDA receptor-regulated protein 1 Apc3 PF12895.2 AAS51399.1 - 0.098 12.8 0.7 0.29 11.3 0.2 2.1 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TIP41 PF04176.8 AAS51400.1 - 7.4e-73 243.6 2.9 1.1e-72 243.1 2.0 1.2 1 0 0 1 1 1 1 TIP41-like family Evr1_Alr PF04777.8 AAS51401.1 - 2.1e-26 91.6 0.2 3.1e-26 91.1 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family G-gamma PF00631.17 AAS51402.1 - 4.8e-28 96.6 0.1 6.5e-28 96.2 0.0 1.2 1 0 0 1 1 1 1 GGL domain Tmemb_14 PF03647.8 AAS51403.1 - 4.9e-24 84.5 7.2 5.8e-24 84.3 5.0 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 AAS51403.1 - 0.073 13.3 3.1 0.14 12.4 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2416) PCI PF01399.22 AAS51405.2 - 1.9e-09 37.7 0.0 3.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 PCI domain IncA PF04156.9 AAS51406.2 - 0.0033 17.0 1.1 0.0033 17.0 0.8 2.0 2 0 0 2 2 2 1 IncA protein CHASE3 PF05227.8 AAS51406.2 - 0.0034 17.0 0.9 0.0061 16.2 0.6 1.3 1 0 0 1 1 1 1 CHASE3 domain Striatin PF08232.7 AAS51406.2 - 0.0088 16.3 3.4 0.0088 16.3 2.3 1.8 2 0 0 2 2 2 1 Striatin family TPD52 PF04201.10 AAS51406.2 - 0.019 14.6 0.3 0.019 14.6 0.2 2.4 2 1 0 2 2 2 0 Tumour protein D52 family MAGSP PF03082.9 AAS51406.2 - 0.048 13.0 0.2 0.072 12.4 0.1 1.2 1 0 0 1 1 1 0 Male accessory gland secretory protein SlyX PF04102.7 AAS51406.2 - 0.13 12.6 4.2 0.32 11.4 0.4 2.7 2 1 1 3 3 3 0 SlyX FliE PF02049.13 AAS51406.2 - 0.17 11.9 2.4 1.6 8.7 0.5 2.4 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE Med9 PF07544.8 AAS51406.2 - 0.61 9.8 5.6 0.7 9.6 0.6 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 YlqD PF11068.3 AAS51406.2 - 0.94 9.5 6.5 0.17 11.9 1.9 1.7 2 0 0 2 2 2 0 YlqD protein V-ATPase_H_N PF03224.9 AAS51407.1 - 1.3e-68 231.4 12.3 1.4e-68 231.2 4.9 2.0 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 AAS51407.1 - 2.1e-39 134.1 2.3 2.1e-39 134.1 1.6 3.1 3 1 0 3 3 3 1 V-ATPase subunit H Mo25 PF08569.6 AAS51407.1 - 0.0055 15.7 10.0 0.0057 15.7 0.1 3.0 4 0 0 4 4 4 2 Mo25-like Arm PF00514.18 AAS51407.1 - 0.0061 16.3 0.8 0.29 11.0 0.2 2.9 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 AAS51407.1 - 0.0075 16.5 0.1 3.1 8.1 0.0 3.3 2 2 1 3 3 3 2 HEAT repeats DUF384 PF04064.8 AAS51407.1 - 0.011 15.2 0.0 0.045 13.3 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF384) DUF2019 PF09450.5 AAS51407.1 - 0.049 13.4 0.1 0.26 11.1 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2019) PIN PF01850.16 AAS51407.1 - 0.098 12.9 3.3 5.5 7.3 0.1 3.4 3 1 1 4 4 4 0 PIN domain Gln-synt_C PF00120.19 AAS51408.1 - 1.2e-62 211.4 0.0 1.4e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 AAS51408.1 - 1.1e-20 72.9 0.0 1.8e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SLS PF14611.1 AAS51408.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Thioredoxin_4 PF13462.1 AAS51409.1 - 1.2e-06 28.6 0.0 2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Actin PF00022.14 AAS51410.1 - 1.2e-55 188.5 0.0 3.5e-38 131.0 0.0 2.0 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 AAS51410.1 - 0.00039 19.1 0.0 0.45 9.0 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein NuA4 PF09340.5 AAS51411.2 - 4.9e-25 86.9 1.8 6.3e-25 86.6 1.3 1.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DUF3896 PF13035.1 AAS51411.2 - 0.05 13.6 6.2 0.071 13.1 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) DUF4164 PF13747.1 AAS51411.2 - 0.11 12.5 1.7 0.16 12.1 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Rho_Binding PF08912.6 AAS51411.2 - 0.56 10.5 7.7 0.92 9.8 5.3 1.4 1 0 0 1 1 1 0 Rho Binding DUF2811 PF10929.3 AAS51411.2 - 1.4 9.0 4.0 8 6.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2811) Prp19 PF08606.6 AAS51411.2 - 1.9 8.2 7.6 4.7 7.0 0.8 2.3 1 1 1 2 2 2 0 Prp19/Pso4-like EssA PF10661.4 AAS51411.2 - 3.1 7.4 6.2 3 7.5 2.1 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA Vfa1 PF08432.5 AAS51411.2 - 3.8 7.4 7.2 4.5 7.2 5.0 1.2 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AIM24 PF01987.12 AAS51412.2 - 1.9e-06 27.4 0.0 2.4e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 tRNA-synt_His PF13393.1 AAS51413.1 - 5.8e-41 140.5 0.1 4.6e-40 137.6 0.0 2.0 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 AAS51413.1 - 6.5e-19 68.1 0.0 4e-18 65.5 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AAS51413.1 - 1.3e-12 47.4 0.0 3e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 AAS51413.1 - 0.011 14.5 0.0 0.3 9.8 0.0 2.4 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 AAS51413.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) IDO PF01231.13 AAS51414.1 - 1e-161 538.1 0.0 1.2e-161 537.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase HemX PF04375.9 AAS51414.1 - 0.019 13.5 0.0 0.039 12.5 0.0 1.4 1 0 0 1 1 1 0 HemX Cid2 PF09774.4 AAS51415.1 - 5.2e-23 81.8 0.0 6.5e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 ARA70 PF12489.3 AAS51415.1 - 0.099 12.6 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Nuclear coactivator Lgl_C PF08596.5 AAS51416.1 - 2.3e-144 480.6 0.0 1.5e-143 477.9 0.0 2.1 2 1 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 AAS51416.1 - 4e-05 23.3 0.2 7.3 6.6 0.0 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF3312 PF11768.3 AAS51416.1 - 0.18 10.0 0.1 0.29 9.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Pkinase PF00069.20 AAS51417.1 - 7.1e-64 215.4 0.0 7e-63 212.1 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51417.1 - 9.9e-35 119.8 0.5 3e-34 118.2 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase HR1 PF02185.11 AAS51417.1 - 8.2e-29 99.1 25.9 1.2e-16 60.1 4.3 3.1 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.17 AAS51417.1 - 9.2e-19 66.9 37.4 1.5e-10 40.6 10.4 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 AAS51417.1 - 4.8e-12 46.1 0.7 1.4e-11 44.6 0.5 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 AAS51417.1 - 0.00099 18.1 1.3 0.016 14.2 0.0 2.4 2 0 0 2 2 2 1 Kinase-like zf-RING_2 PF13639.1 AAS51418.1 - 4.5 7.1 13.0 2.9 7.8 2.2 3.9 4 0 0 4 4 4 0 Ring finger domain zf-HC5HC2H_2 PF13832.1 AAS51419.1 - 2.3e-31 108.0 7.9 2.3e-31 108.0 5.5 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 AAS51419.1 - 2.1e-28 98.2 6.6 2.1e-28 98.2 4.6 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 AAS51419.1 - 5.6e-14 51.1 3.5 5.6e-14 51.1 2.4 2.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 AAS51419.1 - 3.9e-10 39.2 5.3 3.9e-10 39.2 3.7 2.6 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.4 AAS51419.1 - 6.7e-10 39.4 0.0 1.3e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Enhancer of polycomb-like C1_1 PF00130.17 AAS51419.1 - 0.011 15.4 15.5 0.053 13.2 0.3 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 AAS51419.1 - 0.084 12.8 21.4 1.3 9.1 8.3 2.7 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.1 AAS51419.1 - 0.15 11.7 19.5 0.22 11.2 2.2 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 WD40 PF00400.27 AAS51420.1 - 6.6e-14 51.1 4.6 0.00018 21.2 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Pkinase PF00069.20 AAS51422.1 - 2.3e-60 203.9 0.0 3.4e-60 203.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51422.1 - 1.1e-38 132.7 0.0 1.6e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS51422.1 - 0.00023 20.2 0.0 0.00046 19.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DEAD PF00270.24 AAS51423.1 - 5.9e-42 143.0 0.0 9.6e-42 142.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS51423.1 - 1e-25 89.3 0.1 2.4e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 AAS51423.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain PNP_UDP_1 PF01048.15 AAS51424.1 - 9.7e-41 139.2 0.1 1.2e-40 139.0 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.27 AAS51425.1 - 4.3e-40 134.1 19.2 9.7e-09 34.7 0.4 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat YmzC PF14157.1 AAS51425.1 - 0.0034 17.1 0.1 0.69 9.7 0.0 3.2 3 0 0 3 3 3 1 YmzC-like protein TFIIIC_delta PF12657.2 AAS51425.1 - 0.0096 15.6 8.1 0.035 13.8 0.5 3.3 2 1 2 4 4 4 2 Transcription factor IIIC subunit delta N-term Kelch_6 PF13964.1 AAS51425.1 - 0.068 13.3 0.1 12 6.2 0.0 3.1 3 0 0 3 3 3 0 Kelch motif BCS1_N PF08740.6 AAS51426.1 - 2.6e-50 170.6 0.2 4e-50 170.0 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 AAS51426.1 - 1.2e-20 74.0 0.0 5.8e-20 71.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AAS51426.1 - 2.4e-06 28.3 0.0 5.2e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AAS51426.1 - 0.00036 20.6 0.0 0.0029 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AAS51426.1 - 0.00094 19.4 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 AAS51426.1 - 0.0014 18.2 0.0 0.044 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AAS51426.1 - 0.0014 17.6 0.0 0.0033 16.5 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 AAS51426.1 - 0.0016 18.3 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AAS51426.1 - 0.0018 18.1 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 AAS51426.1 - 0.0022 17.9 0.1 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AAS51426.1 - 0.0026 17.4 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 AAS51426.1 - 0.0073 15.8 0.2 1.5 8.3 0.0 2.3 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 AAS51426.1 - 0.0096 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 AAS51426.1 - 0.012 15.0 0.0 0.027 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AAS51426.1 - 0.012 14.6 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.8 AAS51426.1 - 0.017 14.0 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 AAS51426.1 - 0.021 14.3 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 AAS51426.1 - 0.038 14.3 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 AAS51426.1 - 0.04 13.8 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AAS51426.1 - 0.041 14.0 0.0 0.092 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 AAS51426.1 - 0.042 13.5 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain Arch_ATPase PF01637.13 AAS51426.1 - 0.048 13.3 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 AAS51426.1 - 0.06 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 KaiC Miro PF08477.8 AAS51426.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 AAS51426.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AAS51426.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 AAS51426.1 - 0.13 11.8 0.0 0.51 9.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 AAS51426.1 - 0.13 11.6 0.0 0.98 8.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.1 AAS51426.1 - 0.14 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Lipase_GDSL_2 PF13472.1 AAS51427.3 - 7.7e-21 75.0 0.1 9.2e-21 74.7 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AAS51427.3 - 4.6e-20 72.4 0.0 5.3e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pyr_redox_3 PF13738.1 AAS51428.2 - 1.2e-06 28.7 0.0 0.0074 16.3 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AAS51428.2 - 0.00047 19.9 0.0 0.0023 17.7 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 AAS51428.2 - 0.0028 17.6 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AAS51428.2 - 0.039 13.8 0.0 0.24 11.2 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F1F0-ATPsyn_F PF10791.4 AAS51429.2 - 1.8e-43 146.6 0.2 2.1e-43 146.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi LSM PF01423.17 AAS51430.1 - 8e-17 60.5 0.0 9.5e-17 60.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AAS51430.1 - 7e-06 25.8 0.0 8.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain RhoGAP PF00620.22 AAS51431.1 - 3e-42 143.8 0.1 7.1e-42 142.5 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 AAS51431.1 - 1.7e-12 47.1 28.3 1.6e-06 28.0 8.3 2.5 2 0 0 2 2 2 2 LIM domain Seryl_tRNA_N PF02403.17 AAS51431.1 - 0.03 14.3 3.0 0.12 12.4 2.1 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SYCE1 PF15233.1 AAS51431.1 - 0.052 13.4 4.5 0.63 9.9 3.1 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 V_ATPase_I PF01496.14 AAS51431.1 - 0.16 9.8 1.6 0.22 9.3 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 AAS51431.1 - 0.86 9.1 6.8 1.9 8.0 4.7 1.5 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 AAS51431.1 - 9.8 5.7 9.1 5.8 6.4 2.9 2.4 1 1 1 2 2 2 0 Septum formation initiator Complex1_LYR PF05347.10 AAS51432.1 - 5.3e-15 54.9 0.7 6.2e-15 54.7 0.5 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AAS51432.1 - 6.6e-12 45.4 0.6 7.8e-12 45.2 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Glyco_transf_21 PF13506.1 AAS51433.2 - 2.1e-20 72.7 0.0 1.2e-15 57.1 0.0 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 AAS51433.2 - 7.9e-20 71.6 0.0 1e-18 67.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AAS51433.2 - 3.3e-07 30.1 0.0 5.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Zn_clus PF00172.13 AAS51435.2 - 5e-08 32.7 5.3 1.2e-07 31.4 3.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AIRC PF00731.15 AAS51436.1 - 2.7e-64 214.9 1.8 4.6e-64 214.2 1.2 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 AAS51436.1 - 4.8e-61 205.0 0.0 7.6e-61 204.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 AAS51436.1 - 1.1e-09 38.3 0.0 2.2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.14 AAS51436.1 - 4.8e-05 22.5 0.1 0.00011 21.4 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPSase_L_D2 PF02786.12 AAS51436.1 - 0.00024 20.4 0.0 0.0004 19.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 AAS51436.1 - 0.00043 19.7 0.0 0.004 16.5 0.0 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 AAS51436.1 - 0.022 13.5 0.0 0.26 9.9 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 AAS51436.1 - 0.034 14.0 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain TPP_enzyme_N PF02776.13 AAS51437.2 - 1.6e-28 99.3 0.0 2.6e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 AAS51437.2 - 8.5e-21 74.1 0.0 2.1e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 AAS51437.2 - 2.4e-14 53.1 0.0 5.1e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Afi1 PF07792.7 AAS51438.2 - 5.5e-46 156.1 0.4 8.1e-45 152.3 0.0 2.5 3 0 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 AAS51438.2 - 8.3e-34 115.6 0.6 8.3e-34 115.6 0.4 1.8 2 0 0 2 2 2 1 Stabilization of polarity axis Glyco_hydro_47 PF01532.15 AAS51439.1 - 1.7e-82 277.4 0.0 2.1e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Myb_DNA-bind_4 PF13837.1 AAS51440.1 - 3.9e-06 26.8 0.2 7.2e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF4613 PF15390.1 AAS51440.1 - 0.15 10.1 0.9 0.19 9.8 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Myb_DNA-bind_5 PF13873.1 AAS51440.1 - 0.25 11.2 1.5 0.39 10.6 0.3 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SHMT PF00464.14 AAS51441.2 - 5.4e-206 683.6 0.0 6.3e-206 683.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 AAS51441.2 - 3.5e-06 26.0 0.0 6.7e-06 25.0 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AAS51441.2 - 4.2e-05 22.8 0.0 6.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 AAS51441.2 - 0.00022 20.3 0.0 0.00055 18.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II bZIP_2 PF07716.10 AAS51442.2 - 0.00011 22.0 6.9 0.00011 22.0 4.8 1.6 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 AAS51442.2 - 0.0033 17.3 9.8 0.0055 16.6 6.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor RNase_T PF00929.19 AAS51443.1 - 3.3e-29 102.2 0.0 4.1e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Pkinase PF00069.20 AAS51444.2 - 2.1e-57 194.2 0.2 4.5e-36 124.3 1.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51444.2 - 3.4e-25 88.5 0.1 3.3e-20 72.2 0.4 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AAS51444.2 - 1.8e-06 27.1 0.0 7.4e-06 25.1 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Response_reg PF00072.19 AAS51444.2 - 6.8e-06 26.0 0.0 1.8e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain APH PF01636.18 AAS51444.2 - 0.00099 18.8 0.2 0.036 13.7 0.5 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AAS51444.2 - 0.0029 16.7 0.0 0.0062 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS PF00989.19 AAS51444.2 - 0.0085 15.8 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 AAS51444.2 - 0.011 16.1 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.5 AAS51444.2 - 0.021 14.8 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.6 AAS51444.2 - 0.1 11.4 2.1 0.067 12.0 0.2 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 B3_4 PF03483.12 AAS51445.2 - 2.9e-34 118.0 0.0 4.7e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 AAS51445.2 - 3.9e-19 68.2 0.0 2.7e-16 59.1 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 AAS51445.2 - 0.019 14.0 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein SLS PF14611.1 AAS51445.2 - 0.11 11.9 0.1 0.27 10.6 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator DUF726 PF05277.7 AAS51446.1 - 1.9e-129 431.4 1.2 2.9e-129 430.8 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 AAS51446.1 - 0.026 14.2 0.1 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Phostensin_N PF13916.1 AAS51446.1 - 0.1 12.6 0.0 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Ribosomal_L22e PF01776.12 AAS51447.1 - 2.5e-43 146.6 1.0 3e-43 146.3 0.7 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family ADSL_C PF10397.4 AAS51447.1 - 0.14 12.1 0.0 1 9.3 0.0 2.0 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus DUF3115 PF11312.3 AAS51448.1 - 1.1e-98 329.9 0.0 1.3e-98 329.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Mob1_phocein PF03637.12 AAS51449.1 - 4.9e-71 238.0 1.5 6e-71 237.7 1.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family RNA_pol PF00940.14 AAS51450.1 - 2.9e-161 536.5 0.2 4.6e-161 535.8 0.1 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 AAS51450.1 - 3.4e-90 302.5 0.5 3.4e-90 302.5 0.4 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal Tubulin PF00091.20 AAS51451.1 - 2.1e-69 233.6 0.0 3.5e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AAS51451.1 - 9.1e-49 164.6 0.0 1.7e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 AAS51451.1 - 0.0026 17.2 0.0 0.0046 16.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 AAS51451.1 - 0.0045 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Rad51 PF08423.6 AAS51452.1 - 2.9e-138 458.9 0.0 3.7e-138 458.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 AAS51452.1 - 2.7e-14 53.0 0.0 3.9e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 AAS51452.1 - 1.9e-12 47.1 1.6 2.2e-12 46.9 0.2 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 AAS51452.1 - 5.6e-11 42.0 0.0 8e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 AAS51452.1 - 1.1e-06 27.9 0.0 1.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 AAS51452.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 AAS51452.1 - 0.026 13.4 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain HHH PF00633.18 AAS51452.1 - 0.056 13.1 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif PAXNEB PF05625.6 AAS51452.1 - 0.14 10.9 0.1 0.24 10.1 0.1 1.3 1 0 0 1 1 1 0 PAXNEB protein Sel1 PF08238.7 AAS51453.1 - 4.4e-43 144.7 13.1 5.1e-08 33.2 0.3 7.7 7 0 0 7 7 7 7 Sel1 repeat Kinesin PF00225.18 AAS51454.1 - 8.1e-107 356.7 1.7 8.1e-107 356.7 1.2 2.5 3 0 0 3 3 3 1 Kinesin motor domain Apolipoprotein PF01442.13 AAS51454.1 - 4e-05 23.2 23.6 6.5e-05 22.5 7.3 4.3 2 1 1 3 3 3 1 Apolipoprotein A1/A4/E domain OmpH PF03938.9 AAS51454.1 - 0.077 12.9 0.2 0.077 12.9 0.1 4.3 3 2 1 4 4 4 0 Outer membrane protein (OmpH-like) DUF883 PF05957.8 AAS51454.1 - 7.7 6.9 11.6 5 7.5 0.1 5.1 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) eIF3_subunit PF08597.5 AAS51455.1 - 1.2e-60 205.1 21.9 7.6e-60 202.5 15.2 1.8 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit Peroxin-13_N PF04088.8 AAS51456.1 - 6.6e-58 195.1 1.2 9.8e-58 194.5 0.9 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 AAS51456.1 - 1.4e-09 37.1 0.0 2.8e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AAS51456.1 - 1e-07 31.3 0.0 2.4e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AAS51456.1 - 5.3e-07 29.0 0.0 1.3e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 AAS51456.1 - 0.0063 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain MMR1 PF08505.5 AAS51457.1 - 2.3e-66 224.1 3.2 4.1e-66 223.4 2.2 1.4 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein PALP PF00291.20 AAS51458.1 - 7e-73 245.5 0.7 8.6e-73 245.2 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 AAS51458.1 - 1e-40 137.1 0.0 2e-26 91.3 0.0 2.5 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase tRNA-synt_2b PF00587.20 AAS51459.1 - 4.4e-31 107.7 0.0 7.8e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 AAS51459.1 - 0.085 11.6 0.3 0.14 10.9 0.0 1.4 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) Sec61_beta PF03911.11 AAS51460.1 - 4.1e-19 68.0 0.5 5.1e-19 67.7 0.4 1.1 1 0 0 1 1 1 1 Sec61beta family Cas_Csx9 PF09658.5 AAS51460.1 - 0.071 11.8 0.0 0.077 11.7 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) RRM_6 PF14259.1 AAS51461.1 - 2e-08 34.1 0.0 3.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AAS51461.1 - 3e-06 26.7 0.0 6.2e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS51461.1 - 9.8e-06 25.3 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 AAS51461.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif 2 MOZ_SAS PF01853.13 AAS51462.2 - 1.1e-74 249.8 0.8 2.1e-74 248.8 0.6 1.4 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_1 PF00583.19 AAS51462.2 - 0.14 12.1 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family VID27 PF08553.5 AAS51462.2 - 1.9 6.5 10.2 3 5.9 7.1 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Myb_DNA-bind_6 PF13921.1 AAS51463.2 - 3.4e-13 49.4 3.2 3e-10 40.0 0.4 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AAS51463.2 - 1.4e-06 28.2 8.6 4.9e-06 26.5 0.1 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.3 AAS51463.2 - 0.0035 17.1 0.7 0.044 13.6 0.0 2.3 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain TatD_DNase PF01026.16 AAS51464.1 - 2.9e-36 124.9 0.0 3.8e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF721 PF05258.7 AAS51464.1 - 0.046 13.9 0.3 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF721) PP2C PF00481.16 AAS51465.1 - 1.2e-78 264.1 0.0 1.5e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3873 PF12989.2 AAS51465.1 - 0.12 12.4 0.1 0.38 10.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) HTH_38 PF13936.1 AAS51465.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain F-box PF00646.28 AAS51466.1 - 7.9e-05 22.2 0.4 7.9e-05 22.2 0.3 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 AAS51466.1 - 0.0026 17.4 1.3 0.0026 17.4 0.9 2.2 2 0 0 2 2 2 1 F-box-like Zn_clus PF00172.13 AAS51467.2 - 2.8e-08 33.5 9.5 5.5e-08 32.5 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tn7_Tnp_TnsA_C PF08721.6 AAS51467.2 - 0.023 14.7 0.0 0.089 12.8 0.0 2.1 1 0 0 1 1 1 0 TnsA endonuclease C terminal Sugar_transport PF06800.7 AAS51467.2 - 0.027 13.5 0.2 0.045 12.8 0.1 1.3 1 0 0 1 1 1 0 Sugar transport protein Las1 PF04031.8 AAS51468.1 - 8.6e-53 178.1 0.0 2.3e-52 176.7 0.0 1.7 1 0 0 1 1 1 1 Las1-like Latrotoxin_C PF15658.1 AAS51468.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Latrotoxin C-terminal domain RNA_polI_A34 PF08208.6 AAS51469.1 - 7.2e-38 130.2 32.6 6.3e-37 127.1 22.6 2.0 1 1 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Peptidase_S49_N PF08496.5 AAS51469.1 - 1.2 8.9 9.7 0.56 9.9 5.2 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal TFIIE_beta PF02186.10 AAS51470.1 - 1.2e-23 82.8 0.3 2.5e-23 81.8 0.2 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain Sigma70_r3 PF04539.11 AAS51472.1 - 0.037 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 region 3 CRAL_TRIO PF00650.15 AAS51473.1 - 2.6e-24 85.5 0.0 3.6e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AAS51473.1 - 3.7e-10 39.7 0.1 1.1e-09 38.2 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AAS51473.1 - 0.063 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Tim17 PF02466.14 AAS51474.1 - 3.3e-31 107.9 5.5 3.9e-31 107.7 3.8 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.20 AAS51475.1 - 1.1e-53 182.0 0.0 1.9e-53 181.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51475.1 - 8e-25 87.3 0.0 1.2e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AAS51475.1 - 0.0014 18.4 0.1 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 AAS51475.1 - 0.0026 17.1 0.0 0.0075 15.6 0.0 1.7 1 0 0 1 1 1 1 RIO1 family YjcZ PF13990.1 AAS51475.1 - 0.099 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 YjcZ-like protein Choline_kinase PF01633.15 AAS51475.1 - 0.15 11.6 4.1 0.26 10.8 0.0 2.7 2 1 0 3 3 3 0 Choline/ethanolamine kinase RNA_pol_Rpb4 PF03874.11 AAS51476.1 - 5.1e-36 123.2 0.2 8e-36 122.5 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Glyco_transf_15 PF01793.11 AAS51477.1 - 6.2e-132 439.5 1.6 7.4e-132 439.2 1.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosomal_L1 PF00687.16 AAS51478.1 - 2.5e-47 161.0 0.0 3e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DEAD PF00270.24 AAS51479.1 - 6.8e-45 152.5 1.2 1.8e-44 151.1 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS51479.1 - 1.3e-27 95.4 0.2 2.2e-26 91.4 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS51479.1 - 0.00014 21.7 0.1 0.0019 18.0 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AAS51479.1 - 0.00031 20.4 0.5 0.0041 16.8 0.1 2.5 2 1 0 2 2 2 1 Part of AAA domain DUF1253 PF06862.7 AAS51479.1 - 0.0034 15.8 0.3 1.1 7.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) AAA_30 PF13604.1 AAS51479.1 - 0.0047 16.5 0.1 0.062 12.8 0.1 2.3 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.1 AAS51479.1 - 0.02 13.9 0.0 0.046 12.7 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.1 AAS51479.1 - 0.036 14.0 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain Glyco_transf_8 PF01501.15 AAS51480.1 - 1.8e-26 92.9 0.0 3.7e-26 91.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Ribosomal_S21e PF01249.13 AAS51481.1 - 1.2e-39 134.0 0.1 1.3e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e tRNA_U5-meth_tr PF05958.6 AAS51482.1 - 1.7e-19 69.7 0.0 3e-18 65.6 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.15 AAS51482.1 - 2.1e-10 40.2 0.0 4.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.1 AAS51482.1 - 3.6e-10 39.6 0.0 6.7e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS51482.1 - 2.1e-07 31.4 0.0 8e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AAS51482.1 - 2.2e-06 27.7 0.0 4.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 AAS51482.1 - 6.2e-06 25.8 0.1 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 AAS51482.1 - 3.2e-05 23.2 0.1 5.2e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 AAS51482.1 - 8.9e-05 21.9 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.9 AAS51482.1 - 0.00021 20.6 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 AAS51482.1 - 0.00024 21.4 0.0 0.00082 19.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 AAS51482.1 - 0.00056 19.5 0.1 0.0017 17.9 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_11 PF08241.7 AAS51482.1 - 0.0035 17.8 0.0 0.0093 16.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AAS51482.1 - 0.022 13.8 0.0 0.055 12.5 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 AAS51482.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 AAS51482.1 - 0.087 11.9 0.0 0.22 10.5 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ras PF00071.17 AAS51483.1 - 3.6e-46 156.5 0.0 4.7e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS51483.1 - 1.8e-16 60.6 0.0 2.6e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS51483.1 - 3.5e-06 26.3 0.0 4.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DHC_N1 PF08385.7 AAS51484.1 - 1.8e-149 498.8 26.2 1.8e-149 498.8 18.1 5.0 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 AAS51484.1 - 6.3e-115 383.9 8.9 6.3e-115 383.9 6.1 4.1 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 AAS51484.1 - 2.2e-68 230.2 0.0 6.9e-68 228.6 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 Dynein_heavy PF03028.10 AAS51484.1 - 6.9e-48 163.2 0.0 6.9e-48 163.2 0.0 3.3 3 0 0 3 3 3 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 AAS51484.1 - 2.3e-33 115.4 8.8 2.3e-33 115.4 6.1 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 AAS51484.1 - 2.4e-31 108.3 0.0 6.2e-31 107.0 0.0 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 AAS51484.1 - 2e-26 92.3 0.0 2.6e-09 36.9 0.0 6.1 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 AAS51484.1 - 2.5e-24 85.6 0.0 7.2e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 AAS51484.1 - 4.1e-21 75.2 0.1 6.3e-20 71.3 0.0 2.8 2 1 1 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 AAS51484.1 - 7.5e-16 58.4 1.6 0.002 18.2 0.0 7.3 6 0 0 6 6 6 4 AAA domain AAA PF00004.24 AAS51484.1 - 1.7e-15 57.3 0.0 0.041 14.0 0.0 5.2 4 0 0 4 4 4 4 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 AAS51484.1 - 7.8e-09 34.9 0.0 0.0032 16.5 0.0 3.6 3 0 0 3 3 3 2 Zeta toxin AAA_17 PF13207.1 AAS51484.1 - 2e-07 31.8 0.0 1.5 9.6 0.0 5.5 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 AAS51484.1 - 1e-06 28.3 0.4 1.3 8.8 0.0 4.3 4 0 0 4 4 4 2 Part of AAA domain T2SE PF00437.15 AAS51484.1 - 1.3e-06 27.5 8.9 0.0016 17.3 0.0 4.9 5 0 0 5 5 5 2 Type II/IV secretion system protein AAA_16 PF13191.1 AAS51484.1 - 6.7e-06 26.2 2.6 0.44 10.5 0.0 5.6 6 0 0 6 6 5 1 AAA ATPase domain AAA_30 PF13604.1 AAS51484.1 - 2.2e-05 24.1 0.3 0.27 10.7 0.0 4.1 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 AAS51484.1 - 9.4e-05 22.7 5.5 9 6.6 0.0 5.4 5 0 0 5 5 4 0 AAA domain AAA_33 PF13671.1 AAS51484.1 - 0.00037 20.4 0.0 1.5 8.7 0.0 4.4 4 0 0 4 4 4 1 AAA domain MobB PF03205.9 AAS51484.1 - 0.0035 17.0 0.9 0.44 10.2 0.1 3.8 4 0 0 4 4 4 1 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 AAS51484.1 - 0.0058 16.2 0.2 0.93 9.1 0.0 3.6 4 0 0 4 4 4 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 AAS51484.1 - 0.019 14.9 0.2 31 4.4 0.0 4.2 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.13 AAS51484.1 - 0.036 13.5 0.0 8 5.8 0.0 3.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_25 PF13481.1 AAS51484.1 - 0.049 13.0 0.0 8.7 5.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 AAS51484.1 - 0.14 11.3 0.1 4.1 6.4 0.0 3.3 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 AAS51484.1 - 0.17 11.3 0.0 2.1 7.8 0.0 2.7 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Ribosomal_S5_C PF03719.10 AAS51484.1 - 0.46 9.7 0.0 7.7 5.8 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain PAP2 PF01569.16 AAS51485.1 - 4.2e-14 52.3 3.6 4.2e-14 52.3 2.5 2.2 2 1 1 3 3 3 1 PAP2 superfamily Mito_carr PF00153.22 AAS51486.1 - 1.2e-63 210.8 1.3 1e-21 76.4 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Solute_trans_a PF03619.11 AAS51487.1 - 2.1e-87 292.9 13.2 2.4e-87 292.7 9.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha COX14 PF14880.1 AAS51487.1 - 0.039 13.5 0.8 0.092 12.3 0.0 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF1119 PF06550.6 AAS51487.1 - 0.053 12.6 2.8 0.092 11.8 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1119) mIF3 PF14877.1 AAS51488.1 - 2.5e-59 199.6 0.0 3.7e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial translation initiation factor IF3_C PF00707.17 AAS51488.1 - 0.02 14.6 0.0 0.067 12.9 0.0 1.9 2 0 0 2 2 2 0 Translation initiation factor IF-3, C-terminal domain ABC_transp_aux PF09822.4 AAS51488.1 - 0.041 13.3 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system CPSase_L_D2 PF02786.12 AAS51489.2 - 9e-117 387.8 1.6 2.5e-84 281.8 0.0 2.5 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 AAS51489.2 - 6e-48 161.6 0.0 1.5e-47 160.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 AAS51489.2 - 5.9e-45 153.0 0.0 1.4e-44 151.8 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 AAS51489.2 - 9.7e-42 141.9 0.0 2.2e-41 140.8 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 AAS51489.2 - 7.5e-41 138.6 0.5 9.5e-20 70.7 0.0 3.4 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 AAS51489.2 - 6.8e-39 132.4 0.1 3.5e-38 130.1 0.1 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 AAS51489.2 - 6.8e-33 113.9 0.4 4.5e-21 75.4 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 AAS51489.2 - 4e-32 111.2 0.0 2.9e-31 108.4 0.0 2.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 AAS51489.2 - 4.4e-26 91.4 0.3 5.2e-14 51.7 0.0 3.4 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 AAS51489.2 - 4.7e-22 77.7 0.0 3.1e-21 75.0 0.0 2.6 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 AAS51489.2 - 9.8e-16 57.7 2.6 9.5e-09 34.9 0.3 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 AAS51489.2 - 7.6e-15 54.6 0.6 3.3e-07 29.8 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 AAS51489.2 - 4e-08 32.9 0.6 3.6e-06 26.5 0.2 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Peptidase_C26 PF07722.8 AAS51489.2 - 9.5e-08 31.7 0.0 2.4e-06 27.1 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 AAS51489.2 - 4.9e-06 26.4 1.1 0.027 14.3 0.2 2.8 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 AAS51489.2 - 0.075 12.4 0.0 0.25 10.7 0.0 1.9 1 0 0 1 1 1 0 DJ-1/PfpI family zf-H2C2_2 PF13465.1 AAS51490.1 - 3.4e-23 80.7 28.3 1e-09 38.1 0.7 4.7 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 AAS51490.1 - 1.7e-21 75.1 35.0 1.1e-06 28.6 0.3 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS51490.1 - 2.3e-16 58.8 25.2 0.00021 21.3 0.1 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-Di19 PF05605.7 AAS51490.1 - 0.0038 17.3 9.2 0.043 13.9 0.2 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 AAS51490.1 - 0.22 11.5 15.5 3.8 7.5 0.2 4.3 4 0 0 4 4 4 0 Zinc ribbon domain zf-C2H2_jaz PF12171.3 AAS51490.1 - 0.47 10.6 17.8 3.9 7.7 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AAS51490.1 - 0.56 10.1 20.6 0.27 11.1 0.1 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 AAS51490.1 - 0.87 9.8 18.3 11 6.4 0.1 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-CHCC PF10276.4 AAS51490.1 - 2.8 7.8 13.8 1.2 8.9 0.7 3.5 3 0 0 3 3 3 0 Zinc-finger domain zf-BED PF02892.10 AAS51490.1 - 5.7 6.7 23.3 0.46 10.2 0.3 4.3 4 1 1 5 5 5 0 BED zinc finger TRAPP PF04051.11 AAS51491.2 - 2e-30 105.3 0.0 2.8e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component ThaI PF15514.1 AAS51491.2 - 0.085 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease ThaI SH3_9 PF14604.1 AAS51492.2 - 3.7e-28 96.8 0.5 6e-16 57.7 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 AAS51492.2 - 1.8e-26 91.2 0.4 3.2e-13 48.8 0.0 2.9 3 0 0 3 3 3 2 SH3 domain FCH PF00611.18 AAS51492.2 - 1.4e-22 79.6 0.5 7.3e-22 77.3 0.1 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 AAS51492.2 - 5.3e-17 61.0 0.1 3.4e-11 42.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 AAS51492.2 - 0.004 17.2 0.3 0.2 11.8 0.0 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain FHA PF00498.21 AAS51493.1 - 5.7e-15 55.1 0.0 1.3e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 AAS51493.1 - 1.8e-06 27.6 13.3 2.8e-06 27.0 9.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AAS51493.1 - 4.8e-05 23.3 5.1 9e-05 22.5 3.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AAS51493.1 - 0.0064 16.3 6.2 0.013 15.3 4.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 AAS51493.1 - 0.009 15.6 14.8 0.015 14.9 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AAS51493.1 - 0.04 13.6 12.0 0.063 13.0 8.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Sec_GG PF07549.9 AAS51493.1 - 0.061 12.5 0.6 0.13 11.5 0.4 1.5 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-RING-like PF08746.6 AAS51493.1 - 0.29 11.1 10.3 0.59 10.1 7.1 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.1 AAS51493.1 - 0.36 10.8 15.7 0.6 10.1 10.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Malate_synthase PF01274.17 AAS51494.2 - 8.6e-217 720.2 0.0 1e-216 720.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 AAS51494.2 - 0.015 14.2 0.0 0.031 13.1 0.0 1.5 1 1 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family NMT1 PF09084.6 AAS51495.1 - 1.1e-08 34.9 0.0 4e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 AAS51495.1 - 1.8e-08 34.1 0.4 3.5e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 NMT1-like family Phosphonate-bd PF12974.2 AAS51495.1 - 2.4e-08 33.6 0.1 1.6e-07 31.0 0.0 1.7 1 1 1 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein LysR_substrate PF03466.15 AAS51495.1 - 2.3e-06 26.8 2.3 2.3e-06 26.8 1.6 1.9 2 1 0 2 2 2 1 LysR substrate binding domain DCP2 PF05026.8 AAS51496.1 - 1.8e-32 111.0 1.0 4.2e-32 109.8 0.7 1.7 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 AAS51496.1 - 8.5e-14 51.3 0.0 1.9e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF2392 PF10288.4 AAS51497.1 - 3.1e-34 117.5 0.2 8.1e-34 116.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2392) Mqo PF06039.10 AAS51497.1 - 0.045 11.9 0.0 0.083 11.0 0.0 1.4 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Pepsin-I3 PF06394.8 AAS51497.1 - 1.8 8.2 4.4 40 3.9 0.2 3.3 3 0 0 3 3 3 0 Pepsin inhibitor-3-like repeated domain RRM_1 PF00076.17 AAS51500.1 - 1.1e-20 73.0 0.2 9.4e-15 54.0 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS51500.1 - 2.7e-15 56.0 0.2 5.6e-11 42.2 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS51500.1 - 5.2e-10 39.0 0.2 1.4e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 AAS51500.1 - 0.02 14.3 0.0 0.067 12.6 0.0 1.9 1 0 0 1 1 1 0 Sporulation protein family 7 DUF3901 PF13040.1 AAS51500.1 - 0.021 14.0 5.3 0.035 13.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3901) PAD_M PF08527.5 AAS51500.1 - 0.038 13.3 0.1 0.078 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain Nup35_RRM_2 PF14605.1 AAS51500.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SNARE PF05739.14 AAS51501.1 - 3.3e-05 23.4 1.6 3.3e-05 23.4 1.1 2.1 2 0 0 2 2 2 1 SNARE domain PMC2NT PF08066.7 AAS51501.1 - 0.0081 16.4 2.7 2 8.7 0.5 2.4 2 0 0 2 2 2 2 PMC2NT (NUC016) domain TBCA PF02970.11 AAS51501.1 - 0.35 10.9 2.2 0.61 10.1 0.3 2.3 2 1 0 2 2 2 0 Tubulin binding cofactor A FliT PF05400.8 AAS51501.1 - 5.1 7.5 11.7 3 8.3 0.3 3.2 2 1 0 2 2 2 0 Flagellar protein FliT Exo_endo_phos PF03372.18 AAS51503.2 - 1.2e-15 58.1 0.0 1.4e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rota_NS35 PF02509.9 AAS51503.2 - 0.028 13.1 0.0 0.065 11.9 0.0 1.4 1 1 0 1 1 1 0 Rotavirus non-structural protein 35 HhH-GPD PF00730.20 AAS51504.1 - 3.3e-19 69.1 0.0 6.7e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 AAS51504.1 - 0.024 14.3 0.0 0.062 13.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif OmpW PF03922.9 AAS51504.1 - 0.046 13.3 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 OmpW family HEAT PF02985.17 AAS51505.1 - 2.3e-43 142.4 23.9 0.00055 19.7 0.0 12.8 13 0 0 13 13 13 12 HEAT repeat HEAT_2 PF13646.1 AAS51505.1 - 6.2e-34 116.1 1.5 7.4e-07 29.3 0.0 7.9 1 1 7 9 9 9 8 HEAT repeats HEAT_EZ PF13513.1 AAS51505.1 - 1.7e-15 56.9 9.5 0.87 10.1 0.1 9.5 8 1 1 9 9 9 6 HEAT-like repeat Vac14_Fab1_bd PF12755.2 AAS51505.1 - 1.4e-13 51.0 4.0 0.17 12.3 0.0 8.5 3 3 5 9 9 9 4 Vacuolar 14 Fab1-binding region Arm PF00514.18 AAS51505.1 - 0.061 13.1 4.3 6.3 6.7 0.0 5.8 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat MIP-T3 PF10243.4 AAS51506.2 - 0.052 12.0 0.0 0.058 11.8 0.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pkinase PF00069.20 AAS51507.2 - 3.4e-61 206.6 0.0 5.9e-61 205.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51507.2 - 6.8e-24 84.3 0.0 1.1e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS51507.2 - 2.4e-08 33.3 0.0 4.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AAS51507.2 - 7.2e-05 21.9 0.0 0.0013 17.8 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AAS51507.2 - 0.00022 21.0 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 AAS51507.2 - 0.0063 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family G0-G1_switch_2 PF15103.1 AAS51508.2 - 1.4 9.1 5.3 0.67 10.2 0.1 2.4 1 1 1 2 2 2 0 G0/G1 switch protein 2 DUF2104 PF09877.4 AAS51509.1 - 0.72 9.8 6.9 0.07 13.0 0.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) GSH_synth_ATP PF03917.12 AAS51510.1 - 1.4e-112 375.9 0.0 1.8e-112 375.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 AAS51510.1 - 6.4e-35 119.4 0.2 1e-34 118.7 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Med15_fungi PF05397.7 AAS51511.2 - 1.1e-41 141.3 7.0 1.1e-41 141.3 4.9 10.4 7 3 2 9 9 9 1 Mediator complex subunit 15 SNF2_N PF00176.18 AAS51512.1 - 4.6e-67 225.9 0.5 8.1e-67 225.1 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AAS51512.1 - 1.9e-16 59.6 0.0 8.2e-16 57.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS51512.1 - 4.6e-10 39.6 0.0 9.4e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AAS51512.1 - 9e-10 38.2 0.0 3.1e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AAS51512.1 - 0.012 15.7 0.0 0.036 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain RCC1 PF00415.13 AAS51513.2 - 3e-28 97.7 16.9 3e-08 33.7 0.0 8.0 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AAS51513.2 - 3.6e-20 71.0 27.3 1.3e-07 31.0 0.1 6.8 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Exo_endo_phos PF03372.18 AAS51514.1 - 3e-24 86.3 0.0 4.2e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 AAS51514.1 - 2.7e-17 61.9 7.4 3.2e-10 39.3 1.7 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AAS51514.1 - 3.5e-10 39.4 2.1 3.5e-10 39.4 1.4 2.4 2 1 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 AAS51514.1 - 6.7e-09 34.5 11.8 0.0036 17.1 0.1 5.0 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 AAS51514.1 - 2e-07 30.1 6.6 0.005 16.8 0.1 4.7 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 AAS51514.1 - 1.7 8.9 0.0 1.7 8.9 0.0 4.0 5 0 0 5 5 5 0 Leucine Rich repeat Nucleoside_tran PF01733.13 AAS51515.1 - 5.5e-39 134.1 24.8 6e-23 81.4 6.9 2.4 1 1 0 2 2 2 2 Nucleoside transporter PMT PF02366.13 AAS51516.1 - 5.4e-85 284.6 16.5 5.4e-85 284.6 11.4 2.4 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 AAS51516.1 - 4.5e-27 94.8 0.0 7.3e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 MIR domain LDB19 PF13002.2 AAS51517.1 - 7.8e-63 211.4 0.0 1.2e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 AAS51517.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain RasGEF PF00617.14 AAS51518.1 - 2.2e-41 141.6 3.4 2.2e-41 141.6 2.3 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 AAS51518.1 - 1.9e-13 50.4 0.0 9e-13 48.2 0.0 2.3 1 0 0 1 1 1 1 RasGEF N-terminal motif Reo_sigmaC PF04582.7 AAS51518.1 - 0.0045 16.2 5.1 0.011 14.8 3.5 1.6 1 0 0 1 1 1 1 Reovirus sigma C capsid protein TauD PF02668.11 AAS51519.2 - 2.2e-44 152.0 0.9 2.7e-44 151.7 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2427 PF10348.4 AAS51520.1 - 0.019 14.5 9.9 0.053 13.0 6.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) OPT PF03169.10 AAS51521.1 - 8.2e-153 510.1 41.0 9.4e-153 509.9 28.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF983 PF06170.7 AAS51521.1 - 0.045 13.8 7.3 0.23 11.6 5.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF983) HSP20 PF00011.16 AAS51523.1 - 6.4e-20 70.9 0.4 8.3e-20 70.5 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BON PF04972.12 AAS51523.1 - 0.072 12.8 0.0 7.7 6.3 0.0 2.4 2 0 0 2 2 2 0 BON domain NAP PF00956.13 AAS51524.1 - 2.2e-15 56.4 0.1 8.8e-10 38.1 0.0 2.4 1 1 2 3 3 3 2 Nucleosome assembly protein (NAP) SUI1 PF01253.17 AAS51525.1 - 7.9e-29 99.3 0.4 9.5e-29 99.0 0.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2575 PF10837.3 AAS51525.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) Cas_Csa5 PF09702.5 AAS51525.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) Homeobox PF00046.24 AAS51526.3 - 2.3e-16 59.1 1.9 2.9e-16 58.8 1.3 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 AAS51526.3 - 1.5e-05 24.5 0.8 2.3e-05 23.9 0.2 1.5 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.1 AAS51526.3 - 0.18 11.5 0.6 0.4 10.3 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain HMG_box PF00505.14 AAS51527.1 - 0.12 12.6 1.7 2.2 8.6 1.2 2.3 1 1 0 1 1 1 0 HMG (high mobility group) box Metallophos PF00149.23 AAS51528.1 - 0.00022 20.6 3.3 0.00071 19.0 2.3 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Fer4_12 PF13353.1 AAS51528.1 - 0.17 11.9 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain Ribosomal_S4e PF00900.15 AAS51529.1 - 6.6e-33 112.2 1.2 3.9e-32 109.7 0.7 2.0 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 AAS51529.1 - 6.5e-20 70.7 4.4 1.4e-19 69.6 3.1 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 AAS51529.1 - 3.4e-08 32.7 0.5 6.2e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.24 AAS51529.1 - 2.9e-05 23.6 1.2 2.9e-05 23.6 0.8 3.5 4 0 0 4 4 4 1 KOW motif Glyco_hydro_47 PF01532.15 AAS51530.2 - 6.1e-121 404.2 0.5 7.4e-121 403.9 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.20 AAS51531.1 - 4.1e-68 229.3 0.0 6.1e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51531.1 - 1.3e-30 106.3 0.0 2.3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 AAS51531.1 - 1.9e-11 44.3 3.8 1.9e-11 44.3 2.6 2.7 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 AAS51531.1 - 2.5e-09 36.5 0.0 5.4e-09 35.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 AAS51531.1 - 5.3e-07 29.4 0.2 7.4e-06 25.7 0.1 2.4 1 1 0 1 1 1 1 C2 domain YrbL-PhoP_reg PF10707.4 AAS51531.1 - 0.02 14.2 0.0 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HSF_DNA-bind PF00447.12 AAS51532.1 - 3.4e-37 126.7 2.9 1e-36 125.2 2.0 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 AAS51532.1 - 9.1e-28 96.5 0.3 2.2e-27 95.2 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HALZ PF02183.13 AAS51532.1 - 0.0061 16.2 2.7 0.0067 16.1 0.7 1.9 1 1 1 2 2 2 1 Homeobox associated leucine zipper bZIP_1 PF00170.16 AAS51532.1 - 0.021 14.8 1.4 0.021 14.8 1.0 1.7 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.10 AAS51532.1 - 0.039 13.4 1.3 0.078 12.4 0.9 1.5 1 0 0 1 1 1 0 Septum formation initiator CCDC155 PF14662.1 AAS51532.1 - 0.11 12.0 3.3 0.18 11.4 2.3 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF904 PF06005.7 AAS51532.1 - 0.22 11.8 4.1 0.53 10.6 2.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 AAS51532.1 - 0.27 11.5 4.0 1.1 9.6 2.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SET PF00856.23 AAS51533.2 - 6.9e-12 45.9 0.3 1.6e-08 35.0 0.2 2.6 2 1 0 2 2 2 2 SET domain 5-FTHF_cyc-lig PF01812.15 AAS51535.1 - 4.9e-37 127.4 0.0 5.7e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Aminotran_4 PF01063.14 AAS51536.1 - 8.5e-30 103.9 0.0 1e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Glyco_trans_1_4 PF13692.1 AAS51536.1 - 0.11 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 WD40 PF00400.27 AAS51537.1 - 0.003 17.3 1.1 0.14 12.0 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Miro PF08477.8 AAS51538.1 - 0.0047 17.4 0.0 0.032 14.7 0.0 2.4 3 0 0 3 3 3 1 Miro-like protein Ras PF00071.17 AAS51538.1 - 0.012 14.9 0.0 0.77 9.1 0.0 2.6 3 0 0 3 3 3 0 Ras family AAA_28 PF13521.1 AAS51538.1 - 0.08 12.9 0.7 0.25 11.3 0.3 1.9 1 1 1 2 2 2 0 AAA domain Atg14 PF10186.4 AAS51539.1 - 2e-42 145.1 3.4 2.7e-42 144.7 2.4 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 ALIX_LYPXL_bnd PF13949.1 AAS51539.1 - 0.022 13.7 0.1 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV AAA_27 PF13514.1 AAS51539.1 - 0.093 10.4 3.6 0.12 10.0 2.5 1.1 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 AAS51540.1 - 2.1e-61 207.1 0.0 2.9e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AAS51540.1 - 1.8e-16 60.5 0.0 3.8e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AAS51540.1 - 1.3e-13 50.9 1.2 2.7e-13 49.9 0.8 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 AAS51540.1 - 0.0018 18.1 0.4 0.007 16.2 0.3 2.1 1 0 0 1 1 1 1 HAS barrel domain Nucleoplasmin PF03066.10 AAS51540.1 - 0.17 11.3 2.6 0.28 10.7 1.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin RVT_1 PF00078.22 AAS51541.1 - 0.016 14.5 0.1 2.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_20 PF00982.16 AAS51542.1 - 2.4e-199 662.7 0.0 2.8e-199 662.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 AAS51542.1 - 0.00011 21.6 2.3 0.026 13.9 0.1 3.1 3 1 0 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 AAS51542.1 - 0.0052 16.3 0.4 0.018 14.5 0.1 1.9 2 0 0 2 2 2 1 Starch synthase catalytic domain PP2C PF00481.16 AAS51543.2 - 3e-61 207.0 0.6 1.3e-59 201.6 0.0 2.8 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 AAS51543.2 - 0.0024 17.6 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 AAS51543.2 - 0.0053 16.1 0.0 0.018 14.4 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Tau95 PF09734.4 AAS51544.2 - 3.6e-61 207.1 1.0 4.8e-61 206.7 0.7 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Me-amine-dh_H PF06433.6 AAS51545.1 - 0.047 12.3 0.0 0.062 11.9 0.0 1.2 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) Ribosomal_L31 PF01197.13 AAS51545.1 - 0.087 12.8 0.1 0.16 11.9 0.1 1.6 1 1 0 1 1 1 0 Ribosomal protein L31 DIM1 PF02966.11 AAS51546.1 - 2.2e-67 224.6 0.7 2.5e-67 224.4 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 AAS51546.1 - 0.02 14.5 0.1 0.028 14.1 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin DUF3192 PF11399.3 AAS51546.1 - 0.022 14.6 0.1 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) tRNA-synt_2b PF00587.20 AAS51547.1 - 1.2e-71 239.8 0.0 3e-71 238.5 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AAS51547.1 - 1.8e-20 72.6 0.1 3.9e-20 71.5 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain RRM_1 PF00076.17 AAS51549.2 - 4.7e-10 38.9 0.2 2.1e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS51549.2 - 6.5e-09 35.6 0.1 0.00013 21.8 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS51549.2 - 1.9e-06 27.6 0.2 0.012 15.4 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pex14_N PF04695.8 AAS51549.2 - 0.059 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RecX PF02631.11 AAS51549.2 - 0.064 13.4 2.0 0.1 12.8 0.8 1.7 1 1 1 2 2 2 0 RecX family AraC_N PF06719.8 AAS51549.2 - 0.12 11.6 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus GTP_EFTU PF00009.22 AAS51550.1 - 3.7e-58 196.0 0.0 5.1e-58 195.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AAS51550.1 - 5.1e-36 122.8 0.0 1.6e-35 121.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AAS51550.1 - 2.2e-17 62.9 2.2 2.2e-17 62.9 1.5 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 AAS51550.1 - 2.7e-05 23.7 0.9 2.7e-05 23.7 0.6 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 AAS51550.1 - 0.0011 18.9 0.5 0.0033 17.3 0.3 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase CIMR PF00878.13 AAS51551.1 - 3.4e-08 33.3 0.0 0.0027 17.4 0.0 2.4 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 AAS51551.1 - 0.0012 17.9 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Syntaxin PF00804.20 AAS51552.1 - 0.059 13.5 0.6 0.11 12.7 0.4 1.3 1 0 0 1 1 1 0 Syntaxin DUF1640 PF07798.6 AAS51552.1 - 0.13 12.3 1.0 0.18 11.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TFIIA PF03153.8 AAS51553.2 - 0.023 14.5 2.9 0.03 14.2 2.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Na_Ca_ex PF01699.19 AAS51553.2 - 0.093 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Sodium/calcium exchanger protein Transketolase_N PF00456.16 AAS51554.1 - 1.4e-153 510.5 0.0 3e-153 509.5 0.0 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 AAS51554.1 - 1.8e-45 154.6 0.0 3.3e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AAS51554.1 - 1.4e-13 50.8 0.0 2.9e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 AAS51554.1 - 0.00063 18.7 0.1 0.052 12.4 0.0 2.6 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 AAS51554.1 - 0.022 13.5 0.0 0.052 12.2 0.0 1.5 2 0 0 2 2 2 0 Dehydrogenase E1 component TPP_enzyme_N PF02776.13 AAS51554.1 - 0.041 13.3 0.0 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain LMWPc PF01451.16 AAS51555.1 - 7.2e-44 149.4 0.0 8.1e-44 149.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Not3 PF04065.10 AAS51556.1 - 3.5e-79 265.3 33.5 9.1e-77 257.4 23.2 2.2 1 1 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 AAS51556.1 - 5.1e-40 136.4 0.5 1.7e-39 134.7 0.4 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Cep57_MT_bd PF06657.8 AAS51556.1 - 3.2 7.7 13.4 0.24 11.3 3.7 2.8 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ABC_tran_2 PF12848.2 AAS51556.1 - 4.5 7.1 14.1 4.2 7.2 0.0 3.8 3 0 0 3 3 3 0 ABC transporter ORC6 PF05460.8 AAS51557.2 - 0.014 14.5 0.7 0.014 14.5 0.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MerR_2 PF13591.1 AAS51557.2 - 0.12 11.9 0.9 0.21 11.1 0.6 1.3 1 0 0 1 1 1 0 MerR HTH family regulatory protein Acid_PPase PF12689.2 AAS51558.2 - 2.2e-41 141.2 0.0 2.8e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase Ish1 PF10281.4 AAS51559.1 - 5.2e-43 144.7 35.3 5.7e-12 45.4 0.3 7.4 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein SAP PF02037.22 AAS51559.1 - 1.3e-07 30.8 0.0 0.89 9.1 0.0 5.6 5 0 0 5 5 5 2 SAP domain HeH PF12949.2 AAS51559.1 - 0.0002 20.8 0.0 0.2 11.2 0.0 3.5 4 0 0 4 4 4 2 HeH/LEM domain Slx4 PF09494.5 AAS51559.1 - 0.013 15.2 1.6 12 5.7 0.0 4.8 5 0 0 5 5 5 0 Slx4 endonuclease SAP30_Sin3_bdg PF13867.1 AAS51559.1 - 0.018 14.8 0.3 7.5 6.5 0.0 3.3 3 0 0 3 3 3 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF883 PF05957.8 AAS51559.1 - 0.18 12.1 0.1 0.18 12.1 0.1 5.3 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) SAM_2 PF07647.12 AAS51559.1 - 1.8 8.4 9.6 65 3.4 0.0 5.6 7 0 0 7 7 7 0 SAM domain (Sterile alpha motif) Telomere_reg-2 PF10193.4 AAS51561.1 - 0.053 13.7 0.1 14 6.0 0.1 3.0 3 0 0 3 3 3 0 Telomere length regulation protein RPM2 PF08579.6 AAS51562.2 - 4.2e-51 172.1 1.9 1e-50 170.8 0.1 2.6 2 0 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.1 AAS51562.2 - 0.008 16.1 0.0 14 5.7 0.0 4.0 3 0 0 3 3 3 2 PPR repeat family HMG_CoA_synt_C PF08540.5 AAS51563.1 - 1.6e-107 359.1 0.7 2e-107 358.8 0.5 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 AAS51563.1 - 6.1e-93 309.1 0.2 8.7e-93 308.6 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal zf-CCCH PF00642.19 AAS51564.2 - 4.2e-09 35.8 6.2 7.8e-07 28.6 1.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 AAS51564.2 - 2.3e-06 27.3 0.0 3.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AAS51564.2 - 0.0061 16.1 0.0 0.0099 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.1 AAS51564.2 - 7.5 6.7 9.0 17 5.5 1.3 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Proteasome PF00227.21 AAS51565.1 - 3.6e-59 199.2 0.0 4.6e-59 198.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AAS51565.1 - 4.2e-09 35.5 0.7 8e-09 34.6 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Utp14 PF04615.8 AAS51566.1 - 1.9e-202 674.4 68.5 1.9e-202 674.4 47.5 2.0 1 1 1 2 2 2 1 Utp14 protein Prefoldin PF02996.12 AAS51567.2 - 1.1e-26 92.8 4.3 1.1e-26 92.8 3.0 1.3 1 1 0 1 1 1 1 Prefoldin subunit DUF3990 PF13151.1 AAS51567.2 - 0.0027 17.0 0.3 0.0052 16.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) Prefoldin_3 PF13758.1 AAS51567.2 - 0.0035 17.0 1.9 0.0056 16.4 0.1 2.2 2 1 1 3 3 3 1 Prefoldin subunit DUF4537 PF15057.1 AAS51567.2 - 0.016 14.9 0.2 0.026 14.3 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) Omptin PF01278.15 AAS51567.2 - 0.032 13.3 0.3 0.042 12.9 0.2 1.1 1 0 0 1 1 1 0 Omptin family DUF3068 PF11271.3 AAS51567.2 - 0.066 12.2 0.4 0.076 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) TUSC2 PF15000.1 AAS51567.2 - 0.096 12.7 0.5 0.2 11.7 0.2 1.7 1 1 0 1 1 1 0 Tumour suppressor candidate 2 SYCE1 PF15233.1 AAS51567.2 - 0.24 11.3 12.2 1.6 8.6 4.3 2.1 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 DUF406 PF04175.7 AAS51567.2 - 0.86 10.1 5.8 0.44 11.0 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF406) COG2 PF06148.6 AAS51567.2 - 2.2 8.1 8.9 1.7 8.4 0.2 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Rad10 PF03834.9 AAS51568.1 - 1.4e-26 91.9 0.0 2.3e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Asn_synthase PF00733.16 AAS51569.2 - 1.5e-43 149.1 0.0 2.1e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 AAS51569.2 - 2.9e-12 46.4 1.4 9.1e-10 38.3 0.0 4.0 4 1 0 4 4 4 1 Glutamine amidotransferase domain GATase_6 PF13522.1 AAS51569.2 - 1.9e-10 40.7 0.0 2.1e-08 34.1 0.0 2.7 2 1 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 AAS51569.2 - 0.01 15.0 0.0 0.028 13.6 0.0 1.6 2 0 0 2 2 2 0 Aluminium induced protein tRNA_Me_trans PF03054.11 AAS51569.2 - 0.015 13.9 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase VPS9 PF02204.13 AAS51570.1 - 6.4e-27 93.6 0.0 1.1e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 AAS51570.1 - 9.8e-11 40.9 0.0 1.8e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain ERO1 PF04137.10 AAS51571.2 - 3.9e-124 414.2 0.1 5.7e-124 413.7 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PP_kinase_N PF13089.1 AAS51571.2 - 0.0022 18.0 0.4 0.013 15.6 0.1 2.4 2 1 1 3 3 3 1 Polyphosphate kinase N-terminal domain Baculo_LEF-2 PF03041.9 AAS51571.2 - 0.0075 15.9 0.4 0.016 14.8 0.3 1.5 1 0 0 1 1 1 1 lef-2 TFIID-18kDa PF02269.11 AAS51572.1 - 7.5e-30 102.6 0.0 1.1e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 AAS51572.1 - 0.00019 21.5 0.2 0.00041 20.4 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Aerolysin PF01117.15 AAS51572.1 - 0.0047 15.9 0.1 0.0057 15.6 0.0 1.1 1 0 0 1 1 1 1 Aerolysin toxin TAF PF02969.12 AAS51572.1 - 0.043 13.7 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) AMP-binding PF00501.23 AAS51573.2 - 6e-70 235.7 0.0 8.1e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 AAS51573.2 - 6.5e-70 234.8 0.0 1.5e-69 233.7 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 AAS51573.2 - 1.9e-11 44.0 0.0 4.8e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 AAS51573.2 - 2.3e-11 43.5 0.0 5.2e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AAS51573.2 - 5.7e-06 25.2 0.0 3.6e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 AAS51573.2 - 8.5e-05 23.4 0.0 0.00041 21.2 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 AAS51573.2 - 0.0077 15.1 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RAP PF08373.5 AAS51573.2 - 0.21 11.4 0.0 0.49 10.2 0.0 1.6 1 0 0 1 1 1 0 RAP domain SNF2_N PF00176.18 AAS51574.2 - 1.3e-68 230.9 0.0 1.9e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AAS51574.2 - 1.2e-10 41.0 0.0 2.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 AAS51574.2 - 9.7e-09 34.7 5.8 9.7e-09 34.7 4.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 AAS51574.2 - 8.6e-07 28.9 0.0 1.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AAS51574.2 - 1.4e-06 27.9 0.0 2.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 AAS51574.2 - 2.8e-05 24.0 6.6 2.8e-05 24.0 4.5 2.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AAS51574.2 - 3.6e-05 23.4 7.1 3.6e-05 23.4 4.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 AAS51574.2 - 0.00042 19.9 6.1 0.00042 19.9 4.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AAS51574.2 - 0.015 15.0 6.5 0.015 15.0 4.5 2.4 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AAS51574.2 - 0.015 15.1 6.0 0.015 15.1 4.2 2.3 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING DEAD_2 PF06733.10 AAS51574.2 - 0.051 12.9 0.0 0.22 10.8 0.0 2.0 1 1 0 1 1 1 0 DEAD_2 zf-Nse PF11789.3 AAS51574.2 - 0.17 11.4 3.1 0.39 10.2 2.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_Tnp_IS91 PF14319.1 AAS51574.2 - 0.75 9.3 10.7 2.2 7.8 0.8 2.4 2 0 0 2 2 2 0 Transposase zinc-binding domain TPR_1 PF00515.23 AAS51575.2 - 1.1e-50 167.2 15.8 1.8e-07 30.4 0.0 10.0 9 1 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.1 AAS51575.2 - 1.5e-44 149.5 21.8 1.7e-11 43.6 0.1 6.6 2 2 3 6 6 6 6 TPR repeat TPR_2 PF07719.12 AAS51575.2 - 2.2e-43 142.7 21.2 0.0001 21.9 0.0 9.9 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 AAS51575.2 - 1.6e-31 105.8 19.8 0.00062 19.7 0.1 11.0 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.1 AAS51575.2 - 3.1e-30 101.6 10.9 0.018 14.8 0.0 9.6 7 1 2 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 AAS51575.2 - 3.8e-30 103.6 28.8 4.6e-08 32.8 0.3 7.5 3 2 3 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 AAS51575.2 - 3.3e-27 94.5 23.1 1.7e-06 28.5 0.1 6.7 4 3 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 AAS51575.2 - 3.7e-25 86.1 22.5 0.0099 16.4 0.0 10.4 2 2 8 10 10 10 9 Tetratricopeptide repeat TPR_19 PF14559.1 AAS51575.2 - 1.4e-20 73.4 15.6 8.1e-05 22.8 1.4 6.9 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 AAS51575.2 - 1.7e-20 71.1 21.5 0.00095 18.7 0.2 9.2 9 1 1 10 10 9 6 Tetratricopeptide repeat TPR_6 PF13174.1 AAS51575.2 - 1.1e-18 66.3 14.6 0.19 12.2 0.0 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat Apc3 PF12895.2 AAS51575.2 - 6.2e-13 48.6 9.2 3.6e-05 23.8 0.2 4.1 4 0 0 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AAS51575.2 - 5.7e-12 45.3 19.2 4.8e-05 23.1 0.0 5.8 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_15 PF13429.1 AAS51575.2 - 3.5e-10 39.4 15.3 0.00088 18.4 0.2 4.7 1 1 2 4 4 4 3 Tetratricopeptide repeat ChAPs PF09295.5 AAS51575.2 - 0.025 13.3 0.5 1.1 7.9 0.1 2.5 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 AAS51575.2 - 0.037 13.9 0.8 0.037 13.9 0.6 7.8 8 1 1 9 9 8 0 Tetratricopeptide repeat NARP1 PF12569.3 AAS51575.2 - 3.5 6.2 11.0 1.6 7.4 0.0 4.0 4 1 1 5 5 5 0 NMDA receptor-regulated protein 1 EnY2 PF10163.4 AAS51576.1 - 1e-29 102.2 1.4 1.2e-29 102.0 1.0 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 USP8_interact PF08941.5 AAS51576.1 - 0.037 13.3 0.1 0.045 13.0 0.0 1.1 1 0 0 1 1 1 0 USP8 interacting IPPT PF01715.12 AAS51576.1 - 0.084 11.8 0.2 1.2 8.0 0.1 2.0 1 1 0 2 2 2 0 IPP transferase NUDIX PF00293.23 AAS51577.1 - 7.8e-19 67.6 0.5 5.6e-18 64.8 0.0 2.1 1 1 2 3 3 3 1 NUDIX domain Med1 PF10744.4 AAS51578.1 - 5.9e-68 229.4 3.6 1.3e-66 225.0 2.5 2.0 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Troponin-I_N PF11636.3 AAS51578.1 - 0.0016 18.0 0.7 0.0035 16.9 0.5 1.5 1 0 0 1 1 1 1 Troponin I residues 1-32 Spermine_synth PF01564.12 AAS51579.2 - 1.3e-97 325.6 0.0 1.6e-97 325.2 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 AAS51579.2 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AAS51579.2 - 0.0035 17.7 0.0 0.0077 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS51579.2 - 0.0036 16.8 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AAS51579.2 - 0.045 13.1 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.13 AAS51579.2 - 0.062 12.4 0.0 0.86 8.7 0.0 2.1 1 1 1 2 2 2 0 O-methyltransferase Methyltransf_18 PF12847.2 AAS51579.2 - 0.077 13.5 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Hist_deacetyl PF00850.14 AAS51580.2 - 4.9e-67 226.4 1.0 6.6e-67 225.9 0.7 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Glyco_trans_1_4 PF13692.1 AAS51581.2 - 2.7e-13 50.2 0.0 5.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 AAS51581.2 - 2.4e-10 40.7 0.8 2.4e-10 40.7 0.6 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 AAS51581.2 - 3.9e-08 32.9 0.0 5.4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AAS51581.2 - 0.001 19.3 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 EF-hand_1 PF00036.27 AAS51582.1 - 1.9e-29 98.7 3.6 1.7e-08 33.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 AAS51582.1 - 4.4e-26 90.7 0.4 1.4e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AAS51582.1 - 6.4e-25 84.7 2.5 6.3e-08 31.8 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 AAS51582.1 - 2.3e-18 65.5 4.7 4.6e-08 32.5 0.0 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 AAS51582.1 - 1.5e-16 58.8 4.6 1.9e-07 30.1 0.0 4.3 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 AAS51582.1 - 3.9e-12 45.8 0.0 3.2e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 AAS51582.1 - 1.3e-05 25.2 0.2 0.0043 17.0 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 AAS51582.1 - 2e-05 24.1 0.0 0.33 10.6 0.0 2.9 3 1 0 4 4 4 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.8 AAS51582.1 - 0.0016 18.0 0.0 0.86 9.1 0.0 2.2 2 0 0 2 2 2 2 Caleosin related protein EF-hand_4 PF12763.2 AAS51582.1 - 0.005 16.5 0.2 0.016 14.9 0.1 1.7 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF853 PF05872.7 AAS51582.1 - 0.013 13.9 0.2 0.035 12.4 0.1 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF853) TerB PF05099.8 AAS51582.1 - 0.014 15.1 0.1 0.73 9.5 0.0 2.2 2 1 0 2 2 2 0 Tellurite resistance protein TerB ERAP1_C PF11838.3 AAS51582.1 - 0.071 12.3 0.1 0.1 11.8 0.1 1.3 1 1 0 1 1 1 0 ERAP1-like C-terminal domain RNA_pol_Rpb4 PF03874.11 AAS51582.1 - 0.11 12.4 0.9 0.78 9.7 0.0 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb4 Fe-S_biosyn PF01521.15 AAS51586.1 - 1.7e-10 40.8 0.0 5.8e-10 39.0 0.0 1.7 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis ThiF PF00899.16 AAS51587.1 - 1.4e-29 102.6 0.0 3.6e-29 101.3 0.0 1.6 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 AAS51587.1 - 2.2e-18 65.5 0.1 3.7e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 AAS51587.1 - 4e-08 32.4 0.1 9e-08 31.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 AAS51587.1 - 0.0066 16.5 0.0 0.026 14.6 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 AAS51587.1 - 0.055 13.0 0.6 0.26 10.8 0.0 2.3 2 1 0 2 2 2 0 MoeZ/MoeB domain Pneumovirus_M2 PF06436.6 AAS51587.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) Pho88 PF10032.4 AAS51588.2 - 1.7e-82 275.3 0.1 1.9e-82 275.1 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) HMG_box PF00505.14 AAS51589.1 - 7.5e-14 51.7 7.2 2.2e-13 50.2 5.0 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AAS51589.1 - 9.4e-10 38.7 1.5 2.4e-09 37.4 1.1 1.7 1 0 0 1 1 1 1 HMG-box domain DUF4145 PF13643.1 AAS51589.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) Vac_ImportDeg PF09783.4 AAS51590.2 - 3.7e-67 225.2 0.0 4.5e-67 224.9 0.0 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF4405 PF14358.1 AAS51591.2 - 0.12 12.5 0.8 13 5.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) dCMP_cyt_deam_1 PF00383.17 AAS51592.2 - 8.1e-21 73.5 0.0 1.3e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 AAS51592.2 - 0.0017 18.2 0.6 0.0087 15.9 0.6 2.0 1 1 1 2 2 2 1 Bd3614-like deaminase XOO_2897-deam PF14440.1 AAS51592.2 - 0.0095 15.6 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.6 AAS51592.2 - 0.028 14.0 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 APOBEC-like N-terminal domain DnaJ PF00226.26 AAS51593.1 - 3.7e-18 65.0 0.1 5.6e-18 64.4 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Phage_glycop_gL PF11108.3 AAS51593.1 - 0.046 13.6 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Viral glycoprotein L CM_2 PF01817.16 AAS51594.1 - 6.2e-06 26.2 0.0 0.002 18.1 0.0 3.1 2 1 0 2 2 2 2 Chorismate mutase type II SIP1 PF04938.7 AAS51595.1 - 0.0073 15.6 0.1 0.036 13.4 0.0 2.2 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) zf-C2H2_jaz PF12171.3 AAS51596.1 - 0.0039 17.2 1.7 0.01 15.9 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AAS51596.1 - 0.089 13.0 0.3 0.089 13.0 0.2 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type HNH_5 PF14279.1 AAS51596.1 - 1.4 8.9 4.6 4.2 7.4 0.2 2.4 2 0 0 2 2 2 0 HNH endonuclease zf-Di19 PF05605.7 AAS51596.1 - 2.6 8.2 9.9 1.1 9.3 4.5 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 AAS51596.1 - 8.6 6.9 7.7 2.2 8.7 0.1 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Tfb4 PF03850.9 AAS51597.1 - 1.8e-107 358.7 0.1 2.1e-107 358.5 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 AAS51597.1 - 0.0041 17.2 0.0 0.0056 16.8 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain WD40 PF00400.27 AAS51598.2 - 2.2e-35 119.2 6.3 5.8e-08 32.3 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat LisH PF08513.6 AAS51598.2 - 8.3e-10 38.0 1.2 5.8e-08 32.2 0.2 2.4 2 0 0 2 2 2 1 LisH eIF2A PF08662.6 AAS51598.2 - 9e-06 25.5 0.4 0.0011 18.6 0.0 3.4 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A DUF1926 PF09095.6 AAS51598.2 - 0.0063 15.7 0.1 0.0098 15.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1926) DUF3224 PF11528.3 AAS51598.2 - 0.022 14.2 0.0 1.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3224) RAB3GAP2_N PF14655.1 AAS51598.2 - 0.024 13.6 0.0 0.45 9.4 0.0 2.4 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.3 AAS51598.2 - 0.07 11.2 5.0 0.16 10.0 0.1 2.8 2 2 0 3 3 3 0 Nucleoporin Nup120/160 Vps51 PF08700.6 AAS51599.2 - 7.8e-15 54.4 2.2 2.9e-14 52.6 1.5 2.1 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 AAS51599.2 - 1.2e-05 25.1 3.8 5.7e-05 22.9 0.4 3.0 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 AAS51599.2 - 0.00054 19.9 2.1 0.00054 19.9 1.5 3.4 2 1 1 3 3 3 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.9 AAS51599.2 - 0.27 10.8 11.0 0.7 9.5 3.3 3.6 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain IncA PF04156.9 AAS51599.2 - 0.81 9.2 7.2 0.39 10.2 2.1 2.2 2 0 0 2 2 2 0 IncA protein UFD1 PF03152.9 AAS51600.1 - 9.3e-07 28.1 0.0 0.0062 15.6 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 Fes1 PF08609.5 AAS51601.1 - 7.7e-29 100.0 3.5 1.3e-28 99.3 0.5 2.4 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 AAS51601.1 - 1.1e-05 25.5 0.1 6.9e-05 23.0 0.0 2.4 1 1 1 2 2 2 1 HEAT repeats Arm PF00514.18 AAS51601.1 - 0.00024 20.7 0.0 0.1 12.4 0.0 3.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 AAS51601.1 - 0.0012 19.3 0.1 0.011 16.2 0.0 2.7 2 1 1 3 3 3 1 HEAT-like repeat V-ATPase_H_N PF03224.9 AAS51601.1 - 0.0017 17.5 0.3 0.0023 17.1 0.2 1.3 1 0 0 1 1 1 1 V-ATPase subunit H Atx10homo_assoc PF09759.4 AAS51601.1 - 0.0017 18.0 1.2 0.053 13.2 0.0 2.9 3 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.3 AAS51601.1 - 0.002 18.0 0.6 0.0051 16.7 0.4 1.7 1 0 0 1 1 1 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 AAS51601.1 - 0.0021 16.4 1.3 0.003 15.9 0.9 1.3 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit HEAT PF02985.17 AAS51601.1 - 0.0041 17.0 0.0 0.47 10.6 0.0 3.1 2 0 0 2 2 2 1 HEAT repeat UNC45-central PF11701.3 AAS51601.1 - 0.0087 15.7 0.2 0.079 12.6 0.1 2.2 1 1 1 2 2 2 1 Myosin-binding striated muscle assembly central Ric8 PF10165.4 AAS51601.1 - 0.0098 14.7 0.5 0.023 13.5 0.3 1.5 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn DUF4075 PF13294.1 AAS51601.1 - 0.011 15.7 0.2 0.028 14.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) CDC14 PF08045.6 AAS51601.1 - 0.017 14.2 0.2 0.054 12.6 0.0 1.7 1 1 0 2 2 2 0 Cell division control protein 14, SIN component DUF1956 PF09209.6 AAS51601.1 - 0.035 14.0 0.0 34 4.3 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1956) RICTOR_V PF14668.1 AAS51601.1 - 0.059 13.3 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 ERCC4 PF02732.10 AAS51602.2 - 3.6e-11 43.0 0.6 6.8e-11 42.1 0.3 1.5 1 1 0 1 1 1 1 ERCC4 domain Sec8_exocyst PF04048.9 AAS51603.2 - 9.1e-50 167.9 0.4 9.1e-50 167.9 0.3 3.2 2 1 1 3 3 3 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 AAS51603.2 - 7.4e-06 25.0 1.3 7.4e-06 25.0 0.9 2.9 2 1 2 4 4 4 1 Protein of unknown function N-terminal domain (DUF2450) DUF3571 PF12095.3 AAS51603.2 - 0.027 14.7 2.0 1.2 9.3 0.2 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3571) Pkinase PF00069.20 AAS51604.2 - 5.8e-27 94.4 0.0 1.2e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51604.2 - 9.8e-11 41.2 0.0 1.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 AAS51604.2 - 2.4e-10 39.6 6.5 0.21 11.7 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 AAS51604.2 - 1.1e-08 35.2 0.0 0.0042 17.3 0.0 3.5 2 1 0 2 2 2 2 HEAT repeats WD40 PF00400.27 AAS51604.2 - 1.7e-06 27.6 2.7 4.5 7.3 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Kinase-like PF14531.1 AAS51604.2 - 0.0079 15.1 0.0 0.098 11.5 0.0 2.3 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 AAS51604.2 - 0.024 14.3 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HEAT_EZ PF13513.1 AAS51604.2 - 0.17 12.4 0.0 1.6e+02 2.9 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat Pkinase PF00069.20 AAS51605.1 - 7.3e-66 221.9 0.0 9.3e-66 221.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51605.1 - 1.7e-30 105.9 0.0 2.5e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS51605.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like 4HBT_2 PF13279.1 AAS51606.1 - 5.7e-11 42.9 0.1 8.2e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily RXT2_N PF08595.6 AAS51607.1 - 1.3e-45 154.8 0.1 1.3e-45 154.8 0.1 2.5 3 0 0 3 3 3 1 RXT2-like, N-terminal TTL PF03133.10 AAS51608.2 - 2.8e-78 262.8 1.1 3.8e-78 262.3 0.8 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 AAS51608.2 - 7.8e-37 126.4 0.0 1.5e-36 125.5 0.0 1.5 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 AAS51608.2 - 2.8e-06 27.1 0.0 2.8e-05 23.9 0.0 2.4 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AAS51608.2 - 0.00014 20.6 0.0 0.0009 18.0 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_YheCD PF14398.1 AAS51608.2 - 0.0026 16.6 0.0 0.16 10.7 0.0 2.3 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.1 AAS51608.2 - 0.0086 15.2 0.1 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp Nro1 PF12753.2 AAS51608.2 - 0.036 13.0 0.5 0.063 12.2 0.4 1.3 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 GA PF01468.12 AAS51608.2 - 0.17 12.0 0.1 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 GA module zf-Tim10_DDP PF02953.10 AAS51609.2 - 4.3e-15 54.7 0.0 5.3e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger HMG_box PF00505.14 AAS51610.1 - 5e-26 90.7 1.0 5e-26 90.7 0.7 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AAS51610.1 - 6.7e-20 71.2 1.3 6.7e-20 71.2 0.9 1.5 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 AAS51610.1 - 0.0027 17.4 0.8 0.0027 17.4 0.5 2.0 2 1 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 AAS51610.1 - 0.0061 16.7 0.3 0.018 15.2 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) CHDNT PF08073.7 AAS51610.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.8 AAS51610.1 - 0.034 14.3 0.5 0.044 14.0 0.2 1.3 1 1 0 1 1 1 0 YABBY protein PCNA_N PF00705.13 AAS51611.2 - 1.3e-47 160.4 1.4 2.5e-47 159.5 0.6 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 AAS51611.2 - 5.7e-47 158.8 0.3 5.9e-46 155.5 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 AAS51611.2 - 5.5e-08 31.9 0.3 1.8e-06 26.9 0.2 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 AAS51611.2 - 0.00018 20.7 0.0 0.00021 20.5 0.0 1.1 1 0 0 1 1 1 1 Rad9 FOP_dimer PF09398.5 AAS51611.2 - 0.022 14.7 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 FOP N terminal dimerisation domain LmjF365940-deam PF14421.1 AAS51611.2 - 0.094 12.0 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Acetyltransf_1 PF00583.19 AAS51612.1 - 6.2e-19 67.8 0.3 8.6e-19 67.3 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 AAS51612.1 - 2.4e-09 37.2 0.1 4.2e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AAS51612.1 - 2.7e-09 37.0 0.0 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AAS51612.1 - 7.9e-09 35.1 0.1 1.2e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 AAS51612.1 - 1.7e-08 34.5 0.2 2.3e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AAS51612.1 - 1.6e-05 24.7 0.1 9.6e-05 22.2 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AAS51612.1 - 2.3e-05 24.5 0.0 2.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AAS51612.1 - 0.00016 21.4 0.1 0.00029 20.6 0.1 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 AAS51612.1 - 0.013 15.4 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ATG11 PF10377.4 AAS51613.1 - 7.1e-41 139.1 2.6 1.2e-40 138.4 0.0 2.5 2 0 0 2 2 2 1 Autophagy-related protein 11 DUF1664 PF07889.7 AAS51613.1 - 3.5 7.4 24.8 0.76 9.5 0.4 5.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) M_domain PF12938.2 AAS51613.1 - 5.3 6.7 9.4 4.2 7.1 0.0 3.2 3 0 0 3 3 3 0 M domain of GW182 FAD_binding_1 PF00667.15 AAS51614.1 - 6.4e-30 104.2 0.0 1.3e-29 103.2 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 AAS51614.1 - 1.7e-19 70.2 0.0 3.8e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 AAS51614.1 - 2e-15 57.3 0.0 3.7e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4423 PF14394.1 AAS51614.1 - 0.098 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) tRNA-synt_2d PF01409.15 AAS51615.2 - 4.4e-45 153.8 0.1 8e-25 87.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 AAS51615.2 - 1.9e-25 88.8 0.3 5e-25 87.5 0.1 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Ribosomal_L16 PF00252.13 AAS51616.1 - 1.5e-32 112.1 0.2 2.1e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Rep_fac_C PF08542.6 AAS51617.1 - 1.1e-21 76.6 0.1 4.1e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 AAS51617.1 - 3.9e-12 46.1 0.0 8.3e-12 45.0 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 AAS51617.1 - 4.6e-05 23.6 0.1 0.00011 22.3 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 AAS51617.1 - 0.00092 19.2 0.2 1.5 8.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.7 AAS51617.1 - 0.006 15.6 0.2 0.1 11.6 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 AAS51617.1 - 0.0082 15.6 0.0 0.16 11.4 0.0 2.4 2 1 0 2 2 2 1 DNA polymerase III, delta subunit T2SE PF00437.15 AAS51617.1 - 0.016 14.0 0.1 2.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.1 AAS51617.1 - 0.032 14.3 0.2 0.15 12.1 0.2 2.1 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 AAS51617.1 - 0.05 13.5 0.1 0.13 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 AAS51617.1 - 0.17 11.2 0.4 0.48 9.7 0.3 1.7 1 1 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 AAS51617.1 - 0.18 11.2 0.7 1.3 8.4 0.1 2.4 2 1 0 2 2 2 0 FtsK/SpoIIIE family Adaptin_N PF01602.15 AAS51618.1 - 4.9e-82 275.9 9.0 6.3e-82 275.5 6.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 AAS51618.1 - 6.9e-09 35.6 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain HEAT_2 PF13646.1 AAS51618.1 - 0.0017 18.5 0.7 0.015 15.5 0.1 2.8 2 1 1 3 3 3 2 HEAT repeats SapB_2 PF03489.12 AAS51618.1 - 0.54 10.3 0.0 0.54 10.3 0.0 2.9 4 0 0 4 4 4 0 Saposin-like type B, region 2 RPAP3_C PF13877.1 AAS51618.1 - 0.72 9.8 6.1 38 4.3 0.2 4.0 3 1 1 4 4 4 0 Potential Monad-binding region of RPAP3 Ala_racemase_N PF01168.15 AAS51619.1 - 3.3e-41 141.2 0.1 4.1e-41 140.9 0.1 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Anoctamin PF04547.7 AAS51620.1 - 5e-48 163.8 21.5 8.1e-43 146.6 2.2 2.1 1 1 1 2 2 2 2 Calcium-activated chloride channel Pol_alpha_B_N PF08418.5 AAS51621.2 - 6.1e-64 215.9 0.0 8.6e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 AAS51621.2 - 8.2e-45 152.6 0.2 1.1e-44 152.1 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CLASP_N PF12348.3 AAS51622.2 - 5.4e-64 215.6 3.9 1.9e-63 213.8 1.2 2.8 3 0 0 3 3 3 1 CLASP N terminal Como_LCP PF02247.11 AAS51623.1 - 0.022 13.1 0.0 0.026 12.9 0.0 1.1 1 0 0 1 1 1 0 Large coat protein GTP_cyclohydro2 PF00925.15 AAS51624.1 - 3.6e-56 189.0 0.0 2.1e-51 173.4 0.0 2.1 1 1 1 2 2 2 2 GTP cyclohydrolase II RNase_PH PF01138.16 AAS51625.1 - 2.1e-14 53.9 0.3 3e-14 53.4 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AAS51625.1 - 3.9e-05 23.5 0.0 8.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 SpoU_methylase PF00588.14 AAS51626.2 - 5.6e-25 87.8 0.0 1.4e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family PX PF00787.19 AAS51627.1 - 8.2e-22 77.1 0.0 1.9e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 AAS51627.1 - 1.8e-06 27.3 8.5 2.1e-05 23.8 0.6 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 AAS51627.1 - 0.011 15.2 0.6 0.011 15.2 0.4 1.8 2 0 0 2 2 2 0 BAR domain Syntaxin-6_N PF09177.6 AAS51627.1 - 0.03 14.7 1.8 3.8 7.9 0.0 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal B-block_TFIIIC PF04182.7 AAS51627.1 - 0.094 12.5 0.4 17 5.3 0.0 2.5 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC CorA PF01544.13 AAS51627.1 - 0.34 9.8 6.5 0.86 8.5 0.7 2.9 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein adh_short PF00106.20 AAS51628.1 - 4.2e-27 95.0 0.0 6.1e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AAS51628.1 - 1.9e-08 34.1 0.0 7.7e-08 32.1 0.0 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 AAS51628.1 - 0.0015 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AAS51628.1 - 0.0061 16.5 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AAS51628.1 - 0.031 12.9 0.0 0.045 12.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AXE1 PF05448.7 AAS51628.1 - 0.12 10.8 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Polysacc_synt_2 PF02719.10 AAS51628.1 - 0.18 10.6 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 AAS51628.1 - 0.29 10.0 0.8 1.6 7.6 0.2 2.1 1 1 1 2 2 2 0 Male sterility protein DUF1762 PF08574.5 AAS51629.2 - 5e-21 74.8 9.8 5e-21 74.8 6.8 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1762) FAST_2 PF08368.7 AAS51629.2 - 0.13 12.6 0.6 0.31 11.4 0.4 1.6 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 Ribosomal_L6 PF00347.18 AAS51630.1 - 4.8e-31 107.0 10.7 4.1e-17 62.4 3.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 SLS PF14611.1 AAS51630.1 - 0.042 13.2 1.1 0.065 12.6 0.3 1.5 1 1 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator PC4 PF02229.11 AAS51630.1 - 0.14 11.4 1.3 0.32 10.2 0.0 2.2 3 0 0 3 3 3 0 Transcriptional Coactivator p15 (PC4) YbbR PF07949.7 AAS51630.1 - 0.43 10.7 5.4 1.1 9.4 0.4 3.1 1 1 2 3 3 3 0 YbbR-like protein Nup84_Nup100 PF04121.8 AAS51631.1 - 1.4e-239 796.4 9.6 1.6e-239 796.2 6.7 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 SH3_1 PF00018.23 AAS51632.1 - 1.9e-08 33.5 0.2 2.8e-07 29.8 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 AAS51632.1 - 5.5e-07 29.0 0.1 1.4e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AAS51632.1 - 0.00012 21.4 0.1 0.00028 20.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Acetyltransf_2 PF00797.12 AAS51632.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 N-acetyltransferase Chorismate_synt PF01264.16 AAS51633.2 - 1.2e-133 444.9 0.0 1.4e-133 444.7 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase RINT1_TIP1 PF04437.8 AAS51634.1 - 5.5e-117 391.3 22.0 6.8e-117 391.0 15.2 1.1 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Herpes_U44 PF04533.8 AAS51634.1 - 0.022 13.9 1.0 0.45 9.7 0.2 2.5 2 0 0 2 2 2 0 Herpes virus U44 protein HopW1-1 PF15457.1 AAS51634.1 - 0.091 11.7 3.2 0.068 12.1 0.7 1.8 1 1 0 2 2 2 0 Type III T3SS secreted effector HopW1-1/HopPmaA DUF676 PF05057.9 AAS51635.1 - 4.2e-56 189.6 0.0 6.5e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 AAS51635.1 - 0.0025 17.4 0.0 0.03 13.9 0.0 2.2 1 1 1 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 AAS51635.1 - 0.018 14.7 0.0 0.12 12.1 0.0 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.8 AAS51635.1 - 0.037 13.6 0.2 0.13 11.8 0.1 1.9 1 1 0 1 1 1 0 PGAP1-like protein RF-1 PF00472.15 AAS51636.2 - 2.1e-39 133.8 2.5 5e-39 132.6 1.7 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 AAS51636.2 - 1.2e-30 105.6 0.0 3.6e-30 104.0 0.0 1.9 1 0 0 1 1 1 1 PCRF domain FliT PF05400.8 AAS51636.2 - 0.34 11.3 9.0 0.35 11.3 0.3 3.0 3 0 0 3 3 3 0 Flagellar protein FliT Pkinase PF00069.20 AAS51637.1 - 2.1e-69 233.5 0.0 2.4e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51637.1 - 1.4e-29 102.9 0.0 1.9e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS51637.1 - 0.001 18.1 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AAS51637.1 - 0.0032 17.2 0.2 0.0086 15.8 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 AAS51637.1 - 0.0084 15.4 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family TPR_11 PF13414.1 AAS51638.1 - 6.4e-07 28.9 1.4 6e-05 22.6 0.1 3.2 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 AAS51638.1 - 1.8e-05 25.2 1.6 0.011 16.3 0.1 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 AAS51638.1 - 2e-05 24.1 0.6 0.13 12.2 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 AAS51638.1 - 0.00016 21.5 7.4 1.5 8.8 0.0 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat Sel1 PF08238.7 AAS51638.1 - 0.0028 18.2 0.9 1.1 9.9 0.0 3.7 4 0 0 4 4 4 1 Sel1 repeat TPR_8 PF13181.1 AAS51638.1 - 0.013 15.2 2.2 12 5.9 0.0 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 AAS51638.1 - 0.18 12.5 4.9 11 6.9 0.0 4.3 3 1 2 5 5 5 0 Tetratricopeptide repeat Glyco_transf_22 PF03901.12 AAS51639.1 - 2.5e-100 336.4 18.5 3e-100 336.1 12.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HECT PF00632.20 AAS51640.1 - 3.3e-82 276.1 0.1 4.7e-82 275.6 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 AAS51640.1 - 0.071 12.7 4.3 0.1 12.3 1.4 2.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif SPRY PF00622.23 AAS51641.1 - 1.5e-14 54.1 0.0 2.8e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 SPRY domain MMR_HSR1 PF01926.18 AAS51642.2 - 1.9e-09 37.4 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AAS51642.2 - 0.00053 19.4 0.0 0.008 15.6 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 AAS51642.2 - 0.0013 17.9 0.0 0.003 16.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 AAS51642.2 - 0.02 15.2 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AAS51642.2 - 0.03 13.8 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.1 AAS51642.2 - 0.041 12.9 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 AAS51642.2 - 0.048 13.6 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 AAS51642.2 - 0.073 12.8 0.1 0.34 10.7 0.0 2.0 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.13 AAS51642.2 - 0.1 11.9 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B Noc2 PF03715.8 AAS51643.1 - 2.3e-124 414.1 3.1 2.3e-124 414.1 2.2 3.1 3 1 0 3 3 3 2 Noc2p family Mei5 PF10376.4 AAS51644.1 - 2.5e-65 220.1 5.0 2.9e-65 219.8 3.5 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein DDHD PF02862.12 AAS51644.1 - 0.33 10.7 2.6 0.41 10.3 1.8 1.3 1 1 0 1 1 1 0 DDHD domain RNA_pol_Rpb2_6 PF00562.23 AAS51645.2 - 7.2e-120 400.2 2.0 7.4e-120 400.2 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AAS51645.2 - 5.1e-59 198.6 1.9 8.7e-59 197.8 1.3 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 AAS51645.2 - 1.8e-41 141.6 4.5 3.5e-41 140.7 2.9 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 AAS51645.2 - 3.8e-30 103.9 0.1 1.4e-29 102.1 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 AAS51645.2 - 6.3e-27 93.1 1.0 1.8e-26 91.6 0.3 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 AAS51645.2 - 7.4e-19 67.2 0.0 1.7e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 AAS51645.2 - 1.3e-12 47.4 1.3 2.9e-12 46.3 0.3 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 AAS51645.2 - 0.00053 18.4 0.2 0.0013 17.2 0.1 1.6 1 0 0 1 1 1 1 Baculovirus Y142 protein Tfb2 PF03849.9 AAS51646.1 - 2.6e-157 523.1 0.6 3.9e-157 522.5 0.4 1.3 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 AAS51646.1 - 2.3e-05 24.1 0.0 5.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AAS51647.2 - 4.4e-47 159.7 0.0 6.7e-46 155.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS51647.2 - 1e-26 92.6 0.1 2.2e-26 91.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS51647.2 - 0.0068 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 AAS51647.2 - 0.067 11.5 0.0 0.22 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 AAS51647.2 - 0.17 10.9 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AA_permease PF00324.16 AAS51648.1 - 3.7e-116 388.3 37.7 4.2e-116 388.1 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS51648.1 - 1.2e-40 139.3 39.7 1.5e-40 139.0 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease Mit_ribos_Mrp51 PF11709.3 AAS51649.1 - 1e-84 284.4 0.2 1.2e-84 284.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit IGPD PF00475.13 AAS51650.2 - 7.9e-62 207.4 0.4 1.2e-61 206.8 0.3 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase SpoU_methylase PF00588.14 AAS51651.1 - 4.7e-25 88.1 0.0 8.3e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 AAS51651.1 - 8.9e-15 54.6 0.0 2e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding NUDIX PF00293.23 AAS51652.1 - 1.1e-27 96.3 0.0 1.8e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Baculo_PEP_C PF04513.7 AAS51653.2 - 0.00049 19.9 10.8 0.4 10.5 1.7 4.4 2 1 2 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF342 PF03961.8 AAS51653.2 - 0.00085 17.8 9.0 0.00085 17.8 6.3 3.8 2 1 2 4 4 4 2 Protein of unknown function (DUF342) HOOK PF05622.7 AAS51653.2 - 0.12 10.1 42.8 0.0049 14.7 5.0 3.3 3 1 0 3 3 3 0 HOOK protein RGCC PF15151.1 AAS51653.2 - 3.1 8.2 10.2 0.094 13.1 0.6 2.9 3 1 1 4 4 4 0 Response gene to complement 32 protein family Peptidase_C14 PF00656.17 AAS51654.1 - 5.9e-72 242.3 0.0 7.6e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Hist_deacetyl PF00850.14 AAS51655.2 - 4e-62 210.2 0.5 5.5e-62 209.8 0.4 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Mito_carr PF00153.22 AAS51656.1 - 2.2e-55 184.3 4.6 1.9e-18 65.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1772 PF08592.6 AAS51656.1 - 0.085 12.5 0.6 0.19 11.4 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) ING PF12998.2 AAS51657.2 - 9.4e-22 77.2 0.0 4.2e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 AAS51657.2 - 7.6e-09 35.1 8.6 1.4e-08 34.2 5.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 AAS51657.2 - 0.012 15.7 0.8 0.028 14.5 0.6 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Serendipity_A PF05482.7 AAS51657.2 - 0.039 12.3 0.0 0.053 11.9 0.0 1.1 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) WWbp PF10349.4 AAS51657.2 - 0.21 12.5 5.1 0.37 11.6 3.6 1.3 1 0 0 1 1 1 0 WW-domain ligand protein zf-RING-like PF08746.6 AAS51657.2 - 2.4 8.2 5.4 6.4 6.8 3.8 1.8 1 0 0 1 1 1 0 RING-like domain Ras PF00071.17 AAS51658.2 - 3.4e-55 185.8 0.1 4.2e-55 185.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS51658.2 - 1.7e-20 73.6 0.1 2.5e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS51658.2 - 5.8e-10 38.6 0.0 7.1e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AAS51658.2 - 8.7e-06 25.2 0.1 4.3e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AAS51658.2 - 0.00022 21.1 0.0 0.00035 20.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 AAS51658.2 - 0.029 13.5 0.1 0.049 12.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 AAS51658.2 - 0.071 12.5 0.7 0.21 10.9 0.2 2.1 2 1 0 2 2 2 0 AAA domain DAD PF02109.11 AAS51659.1 - 8e-38 128.9 2.3 9.9e-38 128.6 1.6 1.0 1 0 0 1 1 1 1 DAD family CRCB PF02537.10 AAS51659.1 - 0.032 14.0 0.7 0.034 14.0 0.1 1.4 2 0 0 2 2 2 0 CrcB-like protein Y_phosphatase2 PF03162.8 AAS51660.1 - 1.6e-55 186.9 0.0 1.9e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 AAS51660.1 - 9.8e-06 25.9 0.0 6.4e-05 23.2 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family Podoplanin PF05808.6 AAS51661.1 - 0.1 12.1 0.4 0.16 11.5 0.3 1.3 1 0 0 1 1 1 0 Podoplanin UPF0561 PF10573.4 AAS51661.1 - 0.22 11.3 1.5 0.39 10.5 1.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 MFS_1 PF07690.11 AAS51662.1 - 4.3e-38 130.9 32.2 4.3e-38 130.9 22.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AAS51662.1 - 3.1e-06 25.6 1.8 4.4e-06 25.1 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 AAS51662.1 - 0.00053 19.7 0.2 0.64 9.8 0.1 3.0 2 0 0 2 2 2 2 MFS_1 like family DnaJ PF00226.26 AAS51663.1 - 6e-26 89.9 2.5 1e-25 89.2 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AAS51663.1 - 7.9e-22 76.9 0.4 1.7e-18 66.2 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AAS51663.1 - 2.6e-14 53.0 16.5 5.5e-14 51.9 11.4 1.6 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 AAS51663.1 - 0.082 12.5 10.0 0.8 9.4 1.0 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family GRP PF07172.6 AAS51663.1 - 0.15 12.5 8.6 0.41 11.1 5.9 1.8 1 0 0 1 1 1 0 Glycine rich protein family Methyltransf_26 PF13659.1 AAS51664.1 - 2.5e-13 50.0 4.0 2.5e-13 50.0 1.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 AAS51664.1 - 1.5e-11 43.9 0.0 2.2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 AAS51664.1 - 9.7e-11 42.2 0.0 1.5e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS51664.1 - 2e-08 33.9 0.0 2.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AAS51664.1 - 5.3e-07 29.9 0.2 1.1e-06 28.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AAS51664.1 - 7.8e-05 23.0 0.1 0.00036 20.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 AAS51664.1 - 8e-05 22.1 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 AAS51664.1 - 0.0019 17.7 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 AAS51664.1 - 0.0026 16.9 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_10 PF05971.7 AAS51664.1 - 0.0027 16.8 0.0 0.0044 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_12 PF08242.7 AAS51664.1 - 0.0038 17.6 0.0 0.0069 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 AAS51664.1 - 0.052 12.9 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.1 AAS51664.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Gcd10p PF04189.8 AAS51665.1 - 6.8e-103 343.8 0.2 8.2e-103 343.6 0.1 1.1 1 0 0 1 1 1 1 Gcd10p family Nol1_Nop2_Fmu PF01189.12 AAS51666.1 - 3e-108 361.4 0.0 5e-108 360.7 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 AAS51666.1 - 0.00084 18.9 0.0 0.0024 17.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AAS51666.1 - 0.0012 18.9 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Actin PF00022.14 AAS51667.2 - 1.5e-46 158.5 0.0 3.5e-25 88.2 0.0 2.2 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 AAS51667.2 - 0.096 11.2 0.1 0.31 9.5 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein DUF3040 PF11239.3 AAS51667.2 - 1.2 9.2 2.8 0.61 10.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Ras PF00071.17 AAS51668.1 - 2.8e-56 189.3 0.0 3.3e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS51668.1 - 2.8e-17 63.2 0.0 3.7e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS51668.1 - 5.2e-09 35.5 0.0 8.7e-09 34.8 0.0 1.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AAS51668.1 - 0.00076 18.6 0.0 0.00096 18.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 AAS51668.1 - 0.00077 18.7 0.0 0.0011 18.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AAS51668.1 - 0.00088 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 AAS51668.1 - 0.021 13.5 0.0 0.023 13.3 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Arch_ATPase PF01637.13 AAS51668.1 - 0.031 13.9 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 AAS51668.1 - 0.057 13.7 0.0 0.077 13.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter TRP PF06011.7 AAS51669.1 - 0.068 11.7 0.0 0.093 11.2 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Herpes_gE PF02480.11 AAS51669.1 - 0.17 10.1 0.0 0.23 9.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Y_phosphatase2 PF03162.8 AAS51670.1 - 3.3e-51 172.9 0.0 3.9e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 AAS51670.1 - 6.1e-07 29.8 0.0 8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 AAS51670.1 - 0.099 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Aminotran_1_2 PF00155.16 AAS51671.1 - 4.2e-56 190.4 0.0 4.9e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 AAS51671.1 - 1.6e-06 27.0 0.0 2.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Allinase Aminotran_5 PF00266.14 AAS51671.1 - 0.0046 15.7 0.0 0.014 14.1 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AAS51671.1 - 0.009 14.3 0.1 0.026 12.8 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DUF4618 PF15397.1 AAS51672.2 - 0.017 14.5 2.7 0.029 13.6 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Porin_3 PF01459.17 AAS51673.2 - 1.3e-59 201.7 0.0 1.6e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin Vac7 PF12751.2 AAS51674.1 - 5.5e-22 78.1 16.4 3.1e-15 55.9 0.3 3.0 3 0 0 3 3 3 2 Vacuolar segregation subunit 7 DSPc PF00782.15 AAS51675.1 - 6e-36 122.9 0.1 8.3e-36 122.5 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AAS51675.1 - 0.0014 18.0 0.1 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 AAS51675.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Ank_2 PF12796.2 AAS51676.2 - 1.5e-55 185.5 4.3 3.2e-23 81.8 0.3 3.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 AAS51676.2 - 3.3e-42 140.2 3.8 1.9e-11 43.1 0.1 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 AAS51676.2 - 4.1e-31 106.3 3.6 3.3e-09 36.6 0.1 4.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 AAS51676.2 - 2.6e-30 104.2 0.2 1.8e-11 44.1 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 AAS51676.2 - 1.8e-29 98.8 1.1 6.8e-08 32.0 0.1 6.4 6 1 1 7 7 7 4 Ankyrin repeat LMBR1 PF04791.11 AAS51676.2 - 4.2 5.8 8.1 8.3 4.8 5.6 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein COX4 PF02936.9 AAS51677.1 - 1.6e-41 141.3 0.2 1.7e-41 141.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1289 PF06945.8 AAS51677.1 - 0.11 12.0 1.8 6.6 6.2 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) HELP PF03451.9 AAS51678.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 HELP motif COG5 PF10392.4 AAS51679.1 - 5.6e-43 146.0 2.0 5.6e-43 146.0 1.4 2.4 2 0 0 2 2 2 1 Golgi transport complex subunit 5 MutS_III PF05192.13 AAS51679.1 - 0.017 14.8 3.2 0.47 10.1 0.1 2.5 1 1 2 3 3 3 0 MutS domain III Baculo_8kDa PF06096.6 AAS51679.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Baculoviridae 8.2 KDa protein DUF2011 PF09428.5 AAS51680.1 - 1.2e-32 112.5 15.5 1.6e-32 112.0 10.8 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Sec23_trunk PF04811.10 AAS51681.1 - 3.5e-69 232.8 0.1 8.1e-69 231.6 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 AAS51681.1 - 5.9e-25 86.6 0.0 1.5e-24 85.3 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 AAS51681.1 - 2e-18 65.6 7.7 3.4e-18 64.9 5.4 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 AAS51681.1 - 4e-18 65.7 0.1 8.1e-17 61.5 0.1 2.9 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 AAS51681.1 - 1.1e-10 40.9 0.0 2.4e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Metallopep PF12044.3 AAS51682.2 - 3.1e-170 566.2 0.0 3.8e-170 565.9 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 AAS51682.2 - 1.6e-05 24.8 0.0 7.3e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_3 PF13582.1 AAS51682.2 - 0.021 15.3 0.0 0.047 14.2 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 AAS51682.2 - 0.045 13.6 0.2 0.079 12.8 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 AAS51682.2 - 0.11 12.4 0.3 0.24 11.4 0.2 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like 6PF2K PF01591.13 AAS51683.1 - 9.3e-79 263.5 0.1 1.4e-78 263.0 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 AAS51683.1 - 7e-29 100.9 0.3 1.2e-27 96.9 0.0 2.7 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 AAS51683.1 - 3.5e-08 33.4 0.0 8e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AAS51683.1 - 1.7e-06 28.8 0.0 6.5e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AAS51683.1 - 0.00019 20.5 0.0 0.00042 19.4 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.5 AAS51683.1 - 0.00036 19.8 0.0 0.00077 18.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Pox_A28 PF04584.9 AAS51683.1 - 0.0049 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Poxvirus A28 family MMR_HSR1 PF01926.18 AAS51683.1 - 0.0068 16.3 0.0 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 AAS51683.1 - 0.048 13.9 0.4 0.24 11.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain Mob1_phocein PF03637.12 AAS51684.1 - 4e-69 231.7 0.4 4.9e-69 231.4 0.3 1.1 1 0 0 1 1 1 1 Mob1/phocein family Glycos_transf_1 PF00534.15 AAS51685.1 - 3.3e-17 62.4 0.0 6.6e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AAS51685.1 - 0.0015 18.6 0.0 0.0046 17.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF2220 PF09983.4 AAS51685.1 - 0.0042 16.2 0.0 0.0079 15.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) PH PF00169.24 AAS51686.1 - 3.5e-14 52.8 0.5 7.6e-14 51.7 0.3 1.5 1 0 0 1 1 1 1 PH domain Peptidase_M1 PF01433.15 AAS51687.2 - 1.1e-52 179.4 0.0 1.6e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 AAS51687.2 - 2.1e-43 147.3 0.0 5e-43 146.1 0.0 1.6 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 AAS51687.2 - 1.3e-14 54.3 0.2 2.2e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily PRA1 PF03208.14 AAS51688.1 - 4.1e-39 133.3 3.0 4.6e-39 133.2 2.1 1.0 1 0 0 1 1 1 1 PRA1 family protein SUR7 PF06687.7 AAS51688.1 - 1.2 8.6 7.0 2.4 7.6 4.8 1.5 1 1 0 1 1 1 0 SUR7/PalI family DUF2722 PF10846.3 AAS51689.2 - 6.3e-90 302.1 7.2 1.2e-88 298.0 5.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) SHQ1 PF04925.10 AAS51690.1 - 4.1e-71 238.3 0.1 5.8e-71 237.8 0.1 1.2 1 0 0 1 1 1 1 SHQ1 protein Diphthamide_syn PF01866.12 AAS51691.1 - 4e-115 384.2 0.0 5.1e-115 383.9 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein COG6 PF06419.6 AAS51692.2 - 5.1e-168 560.0 19.1 6.6e-168 559.6 13.3 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Pro_CA PF00484.14 AAS51694.1 - 3.3e-34 118.1 0.1 4.3e-34 117.7 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Glyco_hydro_15 PF00723.16 AAS51695.2 - 2.8e-48 164.6 0.0 3.9e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Complex1_LYR_2 PF13233.1 AAS51696.1 - 1.2e-16 61.0 4.3 4.4e-16 59.2 3.0 1.7 1 1 0 1 1 1 1 Complex1_LYR-like Spectrin PF00435.16 AAS51696.1 - 0.44 10.8 5.7 0.91 9.8 3.9 1.4 1 0 0 1 1 1 0 Spectrin repeat DUF3717 PF12512.3 AAS51696.1 - 0.67 9.6 3.4 0.89 9.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3717) Iso_dh PF00180.15 AAS51697.1 - 4.5e-81 272.4 0.1 5.1e-81 272.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF465 PF04325.8 AAS51697.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF465) CLTH PF10607.4 AAS51698.1 - 4.5e-28 97.7 2.4 4.5e-28 97.7 1.7 2.5 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain U-box PF04564.10 AAS51698.1 - 0.013 15.4 0.0 0.055 13.4 0.0 2.1 1 0 0 1 1 1 0 U-box domain DUF2959 PF11172.3 AAS51698.1 - 0.015 15.0 4.7 0.37 10.5 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) TPR_7 PF13176.1 AAS51698.1 - 0.064 13.0 0.1 0.8 9.6 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF342 PF03961.8 AAS51698.1 - 7 4.9 5.8 11 4.2 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2431 PF10354.4 AAS51699.1 - 3.7e-56 189.6 0.0 6e-56 188.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) PIG-H PF10181.4 AAS51700.1 - 1.7e-21 75.5 0.2 3.3e-21 74.6 0.2 1.5 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component Myb_DNA-binding PF00249.26 AAS51701.1 - 5.6e-08 32.7 0.2 1.7e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Mt_ATP-synt_D PF05873.7 AAS51701.1 - 0.015 14.9 2.5 0.015 14.9 1.8 2.2 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) WD40 PF00400.27 AAS51702.1 - 1.2e-12 47.2 2.3 4.9e-06 26.2 0.1 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF2415 PF10313.4 AAS51702.1 - 0.023 14.3 0.3 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Pkinase PF00069.20 AAS51703.2 - 1e-37 129.7 0.0 1.9e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51703.2 - 1.1e-28 99.9 0.0 1.7e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS51703.2 - 2.7e-05 23.2 0.0 4.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AAS51703.2 - 0.21 11.2 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hist_deacetyl PF00850.14 AAS51704.2 - 8.8e-95 317.5 0.0 1.2e-94 317.1 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 AAS51704.2 - 5.4e-52 175.8 0.4 8.2e-52 175.2 0.2 1.3 1 0 0 1 1 1 1 Arb2 domain Nol1_Nop2_Fmu PF01189.12 AAS51705.1 - 2.2e-17 63.3 0.0 1.2e-16 60.9 0.0 1.9 1 1 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 AAS51705.1 - 6e-06 26.2 0.0 0.00037 20.5 0.1 2.3 1 1 1 2 2 2 2 Methyltransferase domain Iso_dh PF00180.15 AAS51706.1 - 7.7e-104 347.3 0.0 9.2e-104 347.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.7 AAS51706.1 - 0.029 13.5 0.0 0.055 12.6 0.0 1.5 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthetic protein PdxA R3H PF01424.17 AAS51707.2 - 7e-13 48.0 0.0 1.4e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 AAS51707.2 - 1.1e-07 31.5 52.5 1.6e-05 24.7 10.1 12.7 14 0 0 14 14 14 5 NF-X1 type zinc finger Methyltransf_16 PF10294.4 AAS51708.1 - 4.1e-56 189.1 0.0 5.3e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MRP-S25 PF13741.1 AAS51709.2 - 7.8e-84 280.7 5.6 9.9e-84 280.4 3.9 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 AAS51709.2 - 0.036 13.9 2.6 0.21 11.4 0.0 3.0 2 1 1 3 3 3 0 Mitochondrial ribosomal protein S23 NFRKB_winged PF14465.1 AAS51709.2 - 0.08 12.7 0.3 2.7 7.8 0.1 2.3 2 0 0 2 2 2 0 NFRKB Winged Helix-like DUF1242 PF06842.7 AAS51710.1 - 1e-17 63.2 0.3 1.3e-17 62.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF1253 PF06862.7 AAS51711.1 - 9.4e-163 541.7 4.6 1.4e-162 541.1 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 AAS51711.1 - 0.00091 18.7 1.8 0.024 14.1 1.3 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase ICE2 PF08426.5 AAS51712.1 - 1.7e-166 553.9 24.7 1.9e-166 553.7 17.1 1.0 1 0 0 1 1 1 1 ICE2 Cyclin_N PF00134.18 AAS51713.1 - 8.7e-17 60.8 1.5 1.9e-16 59.8 0.2 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AAS51713.1 - 0.00011 22.0 0.2 0.049 13.5 0.0 2.5 2 0 0 2 2 2 2 Cyclin, C-terminal domain TRAM_LAG1_CLN8 PF03798.11 AAS51714.1 - 8.7e-38 129.8 23.8 1.5e-37 129.1 16.5 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 AAS51714.1 - 3.4e-16 58.4 2.0 1.4e-15 56.5 0.0 2.8 3 0 0 3 3 3 1 TRAM1-like protein Aa_trans PF01490.13 AAS51715.1 - 4.8e-100 334.9 11.6 5.6e-100 334.6 8.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Y_phosphatase2 PF03162.8 AAS51716.1 - 1.1e-61 207.0 0.0 1.3e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 AAS51716.1 - 2.5e-07 31.0 0.0 3.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 AAS51716.1 - 0.0018 17.6 0.0 0.0025 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 AAS51716.1 - 0.006 16.1 0.0 0.0073 15.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF2416 PF10315.4 AAS51717.1 - 4.6e-37 126.5 1.1 5.8e-37 126.2 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) Histone PF00125.19 AAS51718.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 AAS51718.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AAS51718.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 AAS51718.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 AAS51719.2 - 2.9e-14 52.9 0.2 3.5e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 AAS51719.2 - 5.5e-05 23.0 0.2 8e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 AAS51719.2 - 6.6e-05 23.0 0.1 9.7e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AAS51719.2 - 8e-05 22.6 0.1 0.00015 21.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 AAS51719.2 - 0.003 16.8 0.0 0.0032 16.7 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 AAS51719.2 - 0.0046 16.6 0.0 0.0059 16.3 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 AAS51719.2 - 0.036 14.3 0.1 0.062 13.5 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 AAS51719.2 - 0.14 11.9 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Sds3 PF08598.6 AAS51720.2 - 2.5e-67 226.4 7.2 3.2e-67 226.0 5.0 1.2 1 0 0 1 1 1 1 Sds3-like Met_10 PF02475.11 AAS51721.2 - 5.8e-09 35.8 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 AAS51721.2 - 2.7e-05 23.6 0.0 5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 AAS51721.2 - 0.0026 17.7 0.1 0.0065 16.4 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 AAS51721.2 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase FkbM domain zf-C2H2 PF00096.21 AAS51722.2 - 6.9e-13 48.1 16.2 1.3e-06 28.3 1.9 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AAS51722.2 - 1.8e-12 46.9 10.9 1.8e-07 31.0 0.2 4.3 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 AAS51722.2 - 3.8e-10 39.3 13.2 0.00032 20.8 1.1 3.9 4 0 0 4 4 3 3 C2H2-type zinc finger zf-met PF12874.2 AAS51722.2 - 6.2e-07 29.4 5.2 6.8e-05 22.9 0.5 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AAS51722.2 - 9.9e-06 25.5 7.8 0.0035 17.4 0.5 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn_ribbon_recom PF13408.1 AAS51722.2 - 0.00058 20.0 2.3 0.00058 20.0 1.6 2.2 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain FYVE PF01363.16 AAS51722.2 - 0.16 11.8 4.7 0.29 11.0 3.3 1.5 1 0 0 1 1 1 0 FYVE zinc finger C1_2 PF03107.11 AAS51722.2 - 0.17 12.0 0.9 24 5.1 0.1 2.6 2 0 0 2 2 2 0 C1 domain zf-C2H2_6 PF13912.1 AAS51722.2 - 0.24 11.3 6.1 13 5.8 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 AAS51722.2 - 0.31 10.8 7.1 1.8 8.3 3.0 3.2 2 1 0 2 2 2 0 BED zinc finger C1_4 PF07975.7 AAS51722.2 - 1.6 8.7 4.1 12 6.0 2.9 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain zf-DHHC PF01529.15 AAS51723.1 - 5e-32 110.6 20.4 1.3e-31 109.2 14.1 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase Syja_N PF02383.13 AAS51725.2 - 1.3e-92 309.9 0.1 1.3e-92 309.9 0.1 2.2 2 0 0 2 2 2 1 SacI homology domain DMAP_binding PF06464.6 AAS51725.2 - 2.1 8.9 8.1 0.52 10.9 3.1 1.8 2 0 0 2 2 2 0 DMAP1-binding Domain LCM PF04072.9 AAS51726.1 - 1e-24 87.1 0.0 1.4e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 AAS51726.1 - 8.7e-16 57.4 7.2 1.5e-10 40.7 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 AAS51726.1 - 1.6e-08 34.3 3.4 0.0099 16.0 0.0 5.0 3 1 2 5 5 5 3 Kelch motif Kelch_3 PF13415.1 AAS51726.1 - 2.5e-07 30.6 3.0 0.17 12.0 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 AAS51726.1 - 0.0005 19.7 2.3 1.4 8.7 0.0 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 AAS51726.1 - 0.19 11.3 3.0 9.2 5.9 0.0 4.2 5 0 0 5 5 5 0 Kelch motif DUF3533 PF12051.3 AAS51727.2 - 1.6e-116 389.2 7.0 1.8e-116 389.0 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) CDC50 PF03381.10 AAS51728.2 - 5.4e-88 294.7 0.0 7.2e-88 294.3 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family UPF0029 PF01205.14 AAS51728.2 - 0.087 12.5 0.1 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein family UPF0029 PBP1_TM PF14812.1 AAS51728.2 - 0.14 12.4 5.4 0.39 11.0 3.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aminotran_3 PF00202.16 AAS51729.1 - 3.7e-107 358.1 0.0 4.5e-107 357.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III PapC_C PF13953.1 AAS51729.1 - 0.0042 16.6 0.4 0.016 14.8 0.2 1.9 2 0 0 2 2 2 1 PapC C-terminal domain Aminotran_5 PF00266.14 AAS51729.1 - 0.013 14.2 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.16 AAS51729.1 - 0.015 14.2 0.0 0.049 12.5 0.0 1.8 1 1 0 1 1 1 0 Aminotransferase class I and II IceA2 PF05862.6 AAS51729.1 - 0.056 13.1 0.2 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein Beta_elim_lyase PF01212.16 AAS51729.1 - 0.062 12.4 0.0 0.12 11.4 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase DUF1421 PF07223.6 AAS51730.1 - 0.0065 16.2 36.3 0.0083 15.9 25.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1421) FAM196 PF15265.1 AAS51730.1 - 2.9 7.0 10.8 3.8 6.6 7.5 1.1 1 0 0 1 1 1 0 FAM196 family TFIIA PF03153.8 AAS51730.1 - 4.7 6.9 34.9 6.7 6.5 24.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Na_Ca_ex PF01699.19 AAS51731.2 - 3e-27 94.9 29.5 1.2e-18 67.0 5.8 3.7 4 1 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 AAS51731.2 - 4.2e-13 49.4 3.0 4.2e-13 49.4 2.1 4.3 5 1 0 5 5 5 1 Domain of unknown function (DUF307) IF4E PF01652.13 AAS51732.2 - 8.8e-55 184.7 0.0 1.1e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Abhydrolase_5 PF12695.2 AAS51733.1 - 1.7e-21 76.4 0.0 2.5e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AAS51733.1 - 3.2e-17 63.2 0.0 1.2e-10 41.7 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AAS51733.1 - 6.3e-09 35.7 0.0 2e-05 24.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AAS51733.1 - 7.3e-06 25.3 0.0 0.00014 21.1 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 AAS51733.1 - 0.00018 20.1 0.1 0.098 11.1 0.0 2.7 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 AAS51733.1 - 0.00071 19.3 0.0 0.099 12.3 0.0 2.5 1 1 1 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 AAS51733.1 - 0.0044 16.5 0.0 0.1 12.0 0.0 2.1 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 AAS51733.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase FSH1 PF03959.8 AAS51733.1 - 0.016 14.6 0.0 0.022 14.2 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF1749 PF08538.5 AAS51733.1 - 0.068 12.0 0.1 0.14 10.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) WD40 PF00400.27 AAS51734.2 - 3.8e-17 61.4 14.5 8.8e-08 31.7 0.1 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat zf-rbx1 PF12678.2 AAS51734.2 - 8.6e-05 22.5 2.8 0.00023 21.2 1.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AAS51734.2 - 0.0005 20.0 3.0 0.0005 20.0 2.1 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AAS51734.2 - 0.0025 17.5 3.9 0.0025 17.5 2.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 AAS51734.2 - 0.033 13.8 3.8 0.033 13.8 0.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AAS51734.2 - 0.3 10.9 5.1 0.74 9.6 3.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MFS_1 PF07690.11 AAS51735.1 - 2.7e-22 78.9 36.3 4.8e-09 35.3 5.4 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily SURF4 PF02077.10 AAS51735.1 - 0.013 14.8 0.2 0.032 13.5 0.2 1.6 1 0 0 1 1 1 0 SURF4 family DUF1228 PF06779.9 AAS51735.1 - 0.016 15.1 7.7 0.029 14.4 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) WD40 PF00400.27 AAS51736.1 - 2.2e-45 150.9 12.3 4.5e-10 39.0 0.3 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AAS51736.1 - 0.0033 16.2 4.1 2.8 6.6 0.3 4.1 1 1 2 4 4 4 2 Nup133 N terminal like Nup160 PF11715.3 AAS51736.1 - 0.0095 14.1 0.4 0.13 10.3 0.2 2.3 1 1 0 1 1 1 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 AAS51736.1 - 0.0098 15.6 0.0 1.1 9.0 0.0 3.2 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Apc4_WD40 PF12894.2 AAS51736.1 - 0.043 13.3 0.0 3.5 7.1 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain 6PF2K PF01591.13 AAS51737.1 - 1.1e-52 178.2 0.2 1.7e-52 177.7 0.2 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase KTI12 PF08433.5 AAS51737.1 - 6.2e-05 22.3 0.0 0.0001 21.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 AAS51737.1 - 7e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AAS51737.1 - 0.0025 18.0 0.0 0.0044 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AAS51737.1 - 0.027 15.2 0.0 0.055 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 AAS51737.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 AAS51737.1 - 0.082 11.9 0.1 3.3 6.7 0.0 2.3 2 1 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 AAS51737.1 - 0.15 12.1 0.0 0.4 10.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 AAS51737.1 - 0.17 11.2 0.0 0.88 8.9 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 AAS51737.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Med7 PF05983.6 AAS51738.1 - 6.2e-67 224.4 0.9 7e-67 224.2 0.6 1.0 1 0 0 1 1 1 1 MED7 protein zf-rbx1 PF12678.2 AAS51739.2 - 1.7e-31 108.0 14.1 2.1e-31 107.8 9.8 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AAS51739.2 - 8.3e-17 60.8 10.6 1.1e-16 60.4 7.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 AAS51739.2 - 4.3e-07 29.6 12.6 3.6e-06 26.6 8.8 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AAS51739.2 - 0.0015 18.1 12.4 0.0078 15.8 8.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS51739.2 - 0.0085 16.1 2.4 0.0085 16.1 1.6 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 AAS51739.2 - 0.099 12.1 3.3 0.17 11.4 2.3 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 AAS51739.2 - 0.17 11.5 11.2 14 5.4 7.9 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.1 AAS51739.2 - 0.41 10.8 9.5 28 4.9 6.6 2.1 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 AAS51739.2 - 0.44 10.5 9.7 1.1 9.2 6.7 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 AAS51739.2 - 1.2 9.1 10.1 5.5 7.0 7.1 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 AAS51739.2 - 1.3 8.9 7.0 1.2 9.0 0.3 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 AAS51739.2 - 1.8 8.3 12.0 12 5.7 8.3 2.2 1 1 0 1 1 1 0 zinc-RING finger domain PDT PF00800.13 AAS51740.1 - 9.4e-56 188.2 0.0 1.2e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ATP11 PF06644.6 AAS51741.2 - 9.9e-98 326.8 0.7 1.1e-97 326.6 0.5 1.0 1 0 0 1 1 1 1 ATP11 protein UPF0560 PF10577.4 AAS51741.2 - 0.061 11.5 0.0 0.071 11.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Capsule_synth PF05159.9 AAS51741.2 - 0.17 11.3 1.0 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 Capsule polysaccharide biosynthesis protein DUF883 PF05957.8 AAS51741.2 - 0.79 10.1 3.4 0.94 9.9 1.3 1.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Myb_DNA-bind_5 PF13873.1 AAS51742.1 - 0.0091 15.8 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.12 AAS51742.1 - 0.24 11.4 2.8 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein TPR_11 PF13414.1 AAS51743.2 - 2.1e-13 49.7 6.3 1.3e-08 34.3 0.1 4.9 3 2 2 5 5 5 3 TPR repeat TPR_14 PF13428.1 AAS51743.2 - 4.4e-08 33.0 1.2 0.51 11.1 0.0 6.1 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 AAS51743.2 - 3.1e-07 29.7 4.8 0.0056 16.5 0.0 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 AAS51743.2 - 1.4e-06 28.7 3.2 0.033 14.8 0.0 5.0 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 AAS51743.2 - 2.1e-06 27.9 0.4 0.11 12.8 0.0 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 AAS51743.2 - 2.4e-06 27.3 1.0 0.2 11.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 AAS51743.2 - 1.3e-05 25.0 5.2 0.0037 17.1 0.0 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 AAS51743.2 - 0.00033 20.1 4.4 0.12 11.9 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 AAS51743.2 - 0.0015 18.1 0.5 4.9 7.1 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 AAS51743.2 - 0.023 14.4 1.9 0.42 10.5 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 AAS51743.2 - 0.12 12.2 2.6 6.2 6.7 0.4 3.4 2 2 1 3 3 3 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 AAS51743.2 - 0.14 10.9 0.2 0.28 9.9 0.1 1.4 1 0 0 1 1 1 0 Coatomer WD associated region RPA_C PF08784.6 AAS51744.1 - 2.7e-09 37.3 0.2 1.3e-08 35.1 0.0 2.1 2 1 1 3 3 3 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 AAS51744.1 - 3e-07 30.1 0.2 5e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4539 PF15072.1 AAS51744.1 - 0.072 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Glyco_hydro_72 PF03198.9 AAS51745.1 - 1.5e-132 441.3 0.3 1.9e-132 441.0 0.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 AAS51745.1 - 0.014 14.6 0.1 0.27 10.4 0.1 2.4 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_cc PF11790.3 AAS51745.1 - 0.074 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Lipase_GDSL_2 PF13472.1 AAS51746.2 - 0.14 12.3 0.0 0.66 10.0 0.0 2.1 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family zf-DNL PF05180.7 AAS51747.1 - 5.9e-32 109.2 1.0 8.7e-32 108.6 0.7 1.2 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.8 AAS51747.1 - 0.047 13.3 0.5 0.076 12.7 0.4 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 AAS51747.1 - 0.059 13.0 0.9 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AAS51747.1 - 0.088 12.4 1.1 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 AAS51747.1 - 4 7.1 7.3 12 5.5 0.5 2.2 1 1 2 3 3 3 0 Transcription factor S-II (TFIIS) zf-H2C2_2 PF13465.1 AAS51747.1 - 4.3 7.8 5.7 7.2 7.1 0.3 2.8 1 1 1 2 2 2 0 Zinc-finger double domain CorA PF01544.13 AAS51749.1 - 7.3e-41 140.0 0.1 8.2e-24 84.1 0.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Kri1_C PF12936.2 AAS51750.2 - 4.3e-31 106.7 5.6 4.3e-31 106.7 3.9 4.8 5 1 1 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.7 AAS51750.2 - 2.4e-16 59.8 15.2 2.4e-16 59.8 10.6 5.7 5 1 0 5 5 5 1 KRI1-like family EST1 PF10374.4 AAS51750.2 - 0.03 14.3 0.0 0.23 11.4 0.0 2.4 2 1 1 3 3 3 0 Telomerase activating protein Est1 DAP PF15228.1 AAS51750.2 - 0.036 14.7 1.8 0.036 14.7 1.3 3.9 4 0 0 4 4 4 0 Death-associated protein DUF3915 PF13054.1 AAS51750.2 - 3.9 7.4 5.8 3 7.8 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) UPF0220 PF05255.6 AAS51751.1 - 1.6e-63 212.9 0.8 1.8e-63 212.7 0.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Pkinase PF00069.20 AAS51752.1 - 2.5e-58 197.2 0.0 3e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51752.1 - 5.7e-30 104.2 0.0 7.6e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS51752.1 - 8.5e-07 28.2 0.0 2.6e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AAS51752.1 - 0.00071 19.3 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AAS51752.1 - 0.0048 15.9 0.0 0.0079 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 AAS51752.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_S11 PF00411.14 AAS51753.1 - 1.5e-07 31.5 0.0 5.9e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S11 Ribosomal_L23 PF00276.15 AAS51754.1 - 3.2e-20 71.8 2.7 3.2e-20 71.8 1.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 AAS51754.1 - 4e-20 71.5 9.1 4e-20 71.5 6.3 2.4 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Hydant_A_N PF05378.8 AAS51754.1 - 0.043 13.3 0.6 0.063 12.7 0.4 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region DUF3481 PF11980.3 AAS51755.2 - 0.0045 16.7 3.6 0.5 10.2 0.1 2.9 2 1 1 3 3 3 2 Domain of unknown function (DUF3481) DUF347 PF03988.7 AAS51755.2 - 2.3 8.1 8.3 1.8 8.5 0.3 3.0 2 1 0 2 2 2 0 Repeat of Unknown Function (DUF347) SPC25 PF06703.6 AAS51755.2 - 5.2 6.6 7.2 0.51 9.9 0.8 2.3 3 1 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) FtsX PF02687.16 AAS51755.2 - 5.9 6.6 15.0 2.8 7.7 1.1 3.5 1 1 3 4 4 4 0 FtsX-like permease family Ldh_1_N PF00056.18 AAS51756.1 - 7.2e-39 132.8 0.6 1.6e-38 131.7 0.4 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 AAS51756.1 - 1.9e-33 115.6 0.0 4.4e-33 114.4 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain THF_DHG_CYH_C PF02882.14 AAS51756.1 - 0.025 13.6 1.1 1.2 8.1 0.8 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 AAS51756.1 - 0.17 11.8 2.0 2.5 8.0 0.0 2.6 1 1 1 2 2 2 0 NADH(P)-binding TRM13 PF05206.9 AAS51757.2 - 7.9e-72 241.6 0.0 1.2e-71 241.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 AAS51757.2 - 1.8e-13 49.5 1.8 1.8e-13 49.5 1.3 1.9 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.7 AAS51757.2 - 7.3e-09 35.1 0.4 1.5e-08 34.1 0.3 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 AAS51757.2 - 0.043 13.4 3.6 0.88 9.2 2.5 2.3 1 1 0 1 1 1 0 Methyltransferase domain Ras PF00071.17 AAS51758.2 - 1.5e-32 112.2 0.1 2.9e-28 98.2 0.0 2.3 2 0 0 2 2 2 2 Ras family Miro PF08477.8 AAS51758.2 - 7.1e-11 42.6 0.0 5.5e-08 33.3 0.0 2.5 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS51758.2 - 1e-06 28.1 0.0 1.3e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AAS51758.2 - 3.8e-05 22.9 0.2 0.00045 19.4 0.1 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_5 PF07728.9 AAS51758.2 - 0.023 14.4 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AAS51758.2 - 0.039 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 AAS51758.2 - 0.05 13.0 0.0 0.087 12.2 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain G-alpha PF00503.15 AAS51758.2 - 0.06 12.0 0.3 10 4.7 0.0 2.9 1 1 0 2 2 2 0 G-protein alpha subunit UPF0020 PF01170.13 AAS51759.1 - 3.5e-12 46.2 0.0 6.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 AAS51759.1 - 8.8e-10 38.6 0.0 2.1e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.10 AAS51759.1 - 0.032 13.6 0.0 3.4 7.0 0.0 2.5 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Cons_hypoth95 PF03602.10 AAS51759.1 - 0.047 13.0 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RRM_1 PF00076.17 AAS51760.2 - 2.7e-37 126.2 0.2 5.1e-19 67.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS51760.2 - 7.3e-34 115.5 0.0 1.4e-16 60.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS51760.2 - 2.2e-13 49.8 0.0 7.7e-07 28.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AAS51760.2 - 0.061 13.1 0.1 0.87 9.4 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif PAT1 PF09770.4 AAS51760.2 - 0.77 7.9 31.2 0.32 9.1 8.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 AAS51760.2 - 5.9 6.6 27.9 0.33 10.8 7.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nramp PF01566.13 AAS51761.1 - 1.6e-87 293.6 13.0 2.7e-87 292.9 9.0 1.4 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF2964 PF11177.3 AAS51761.1 - 1.6 8.6 6.5 19 5.2 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) Ribosomal_S19e PF01090.14 AAS51762.1 - 2.9e-56 188.7 0.1 3.3e-56 188.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L18e PF00828.14 AAS51763.1 - 3.9e-23 82.2 0.0 7.2e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Secretin_N PF03958.12 AAS51763.1 - 0.1 12.8 0.1 0.21 11.8 0.1 1.6 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain MFS_1 PF07690.11 AAS51764.2 - 1.8e-30 105.8 39.6 1.8e-30 105.8 27.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AAS51764.2 - 7.5e-05 21.4 47.2 0.0006 18.4 15.7 4.4 1 1 1 2 2 2 1 Sugar (and other) transporter Myc_target_1 PF15179.1 AAS51764.2 - 0.11 12.0 0.7 0.23 11.0 0.5 1.5 1 0 0 1 1 1 0 Myc target protein 1 MFS_1 PF07690.11 AAS51765.1 - 1.2e-26 93.2 33.5 1.2e-26 93.2 23.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Myc_target_1 PF15179.1 AAS51765.1 - 0.2 11.2 0.4 0.38 10.2 0.3 1.4 1 0 0 1 1 1 0 Myc target protein 1 Redoxin PF08534.5 AAS51766.1 - 2.1e-31 108.4 0.0 2.5e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 AAS51766.1 - 2.6e-08 33.5 0.0 3.4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family S-AdoMet_synt_C PF02773.11 AAS51766.1 - 0.014 15.1 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, C-terminal domain GCR1_C PF12550.3 AAS51768.1 - 1.2e-25 89.2 0.1 2.7e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF4232 PF14016.1 AAS51769.1 - 0.049 13.2 1.3 0.14 11.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) Kelch_3 PF13415.1 AAS51771.2 - 2.9e-36 122.8 1.4 7.6e-06 25.9 0.0 5.9 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 AAS51771.2 - 8.5e-33 111.7 7.7 9.6e-06 25.4 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 AAS51771.2 - 1.4e-24 85.6 8.4 0.00017 21.2 0.2 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 AAS51771.2 - 7.1e-22 76.6 5.4 5.1e-05 23.2 0.1 6.3 4 1 2 6 6 6 4 Kelch motif Kelch_1 PF01344.20 AAS51771.2 - 4.8e-20 70.8 3.7 2e-07 30.4 0.1 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 AAS51771.2 - 4.9e-10 38.7 5.4 0.1 12.4 0.0 6.1 6 0 0 6 6 6 3 Kelch motif RAG2 PF03089.9 AAS51771.2 - 0.0039 15.9 0.0 0.15 10.7 0.0 2.5 2 1 0 2 2 2 1 Recombination activating protein 2 CALCOCO1 PF07888.6 AAS51771.2 - 0.019 13.3 27.7 1.5 7.0 11.1 2.5 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4201 PF13870.1 AAS51771.2 - 1.3 8.4 34.8 1 8.7 9.6 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) HALZ PF02183.13 AAS51771.2 - 3.3 7.5 36.6 1 9.1 3.8 5.8 5 1 0 5 5 5 0 Homeobox associated leucine zipper ApoO PF09769.4 AAS51774.1 - 1.1e-41 142.1 0.1 1.7e-41 141.5 0.1 1.3 1 0 0 1 1 1 1 Apolipoprotein O DUF4166 PF13761.1 AAS51774.1 - 0.088 12.6 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4166) BRCT PF00533.21 AAS51775.1 - 1.3e-23 82.9 1.5 1.7e-07 31.3 0.0 6.1 5 1 0 5 5 5 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AAS51775.1 - 1e-21 76.4 1.9 1.4e-15 56.8 0.1 4.1 5 0 0 5 5 5 2 twin BRCT domain Cir_N PF10197.4 AAS51776.1 - 2.9e-06 27.1 1.0 2.9e-06 27.1 0.7 1.7 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.3 AAS51776.1 - 0.022 15.2 0.2 0.043 14.2 0.0 1.7 2 0 0 2 2 2 0 Pre-mRNA splicing factor Ank_2 PF12796.2 AAS51777.2 - 3.2e-31 107.5 1.2 3e-14 53.1 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) SPX PF03105.14 AAS51777.2 - 3.1e-29 102.6 4.0 1.3e-14 54.6 0.9 2.4 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 AAS51777.2 - 2e-28 96.7 5.3 2.9e-06 26.7 0.1 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 AAS51777.2 - 6.5e-23 80.6 2.7 3.5e-06 27.3 0.0 4.9 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 AAS51777.2 - 9.7e-22 76.5 5.2 3.7e-05 23.8 0.0 5.6 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 AAS51777.2 - 4.6e-21 72.8 4.4 4.2e-05 23.3 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_2 PF12796.2 AAS51778.2 - 3.6e-34 116.9 4.2 6.2e-11 42.4 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 AAS51778.2 - 1.5e-31 106.5 5.2 7.1e-09 35.0 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 AAS51778.2 - 1.5e-29 99.0 1.6 5.9e-06 26.0 0.0 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 AAS51778.2 - 1.1e-26 92.6 6.1 1e-07 32.2 0.0 5.8 1 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 AAS51778.2 - 2.3e-25 88.0 7.7 1.3e-06 28.4 0.0 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Band_7 PF01145.20 AAS51779.1 - 2.9e-23 82.6 0.7 4e-23 82.2 0.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Spo12 PF05032.7 AAS51780.2 - 1.6e-19 69.2 1.7 1.6e-19 69.2 1.2 2.1 2 0 0 2 2 2 1 Spo12 family DAP PF15228.1 AAS51780.2 - 0.18 12.5 7.0 0.19 12.4 4.0 1.9 1 1 1 2 2 2 0 Death-associated protein SMI1_KNR4 PF09346.5 AAS51781.2 - 1.2e-35 122.4 0.0 3.2e-35 120.9 0.0 1.8 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) DIE2_ALG10 PF04922.7 AAS51782.2 - 4e-113 378.2 34.5 4e-113 378.2 23.9 1.4 2 0 0 2 2 2 1 DIE2/ALG10 family Lectin_C PF00059.16 AAS51783.2 - 7.5e-05 23.3 0.4 0.0082 16.7 0.4 2.5 2 0 0 2 2 2 2 Lectin C-type domain Pex24p PF06398.6 AAS51784.1 - 1.9e-80 270.3 0.7 2.6e-80 269.9 0.5 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin NAAA-beta PF15508.1 AAS51784.1 - 0.0054 17.0 0.1 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF639 PF04842.7 AAS51784.1 - 0.018 13.2 0.2 0.026 12.7 0.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Herpes_LMP1 PF05297.6 AAS51784.1 - 0.37 9.6 3.7 0.46 9.3 0.1 2.1 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) 2TM PF13239.1 AAS51784.1 - 1.5 8.9 3.8 0.36 10.9 0.1 2.0 2 0 0 2 2 2 0 2TM domain WD40 PF00400.27 AAS51785.2 - 3.8e-12 45.5 10.4 0.0014 18.4 0.0 6.2 8 0 0 8 8 8 4 WD domain, G-beta repeat WD40 PF00400.27 AAS51786.1 - 0.00018 21.2 0.0 0.016 15.0 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat RRM_5 PF13893.1 AAS51787.2 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AAS51787.2 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SKG6 PF08693.5 AAS51788.2 - 1.8e-06 27.1 1.3 3.2e-06 26.3 0.9 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 AAS51788.2 - 0.043 13.3 0.4 0.53 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Ribosomal_S4 PF00163.14 AAS51789.1 - 3.7e-22 78.5 3.8 7e-22 77.6 1.9 1.8 2 1 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 AAS51789.1 - 5.6e-12 44.9 0.0 1.1e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_L6 PF00347.18 AAS51790.2 - 3.3e-18 65.9 0.0 6.2e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L3 PF00297.17 AAS51791.2 - 6.4e-42 143.7 7.8 1.1e-40 139.6 5.4 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 CRM1_C PF08767.6 AAS51792.2 - 4.3e-131 436.5 2.6 4.3e-131 436.5 1.8 3.3 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 AAS51792.2 - 7.6e-38 129.7 6.5 7.6e-38 129.7 4.5 3.8 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 AAS51792.2 - 1.9e-12 46.9 3.6 7.2e-12 45.0 0.0 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Ribosomal_L2_C PF03947.13 AAS51793.1 - 1.5e-40 137.9 2.3 2.5e-40 137.2 1.6 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 AAS51793.1 - 5.2e-13 48.7 0.1 1.2e-12 47.5 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain RRM_1 PF00076.17 AAS51794.1 - 1.6e-20 72.4 0.0 5.1e-11 42.0 0.0 2.9 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS51794.1 - 2.6e-20 72.1 0.0 1.3e-11 44.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS51794.1 - 5.8e-09 35.6 0.0 0.00023 20.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L29e PF01779.12 AAS51795.1 - 8.8e-22 76.6 11.2 1.3e-21 76.1 7.7 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family UCR_hinge PF02320.11 AAS51796.1 - 1.4e-26 92.1 3.5 2.7e-26 91.2 2.4 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 AAS51796.1 - 0.00051 19.7 10.0 0.00056 19.5 7.0 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region Erythro_esteras PF05139.9 AAS51796.1 - 0.027 13.6 3.9 0.03 13.5 2.7 1.2 1 0 0 1 1 1 0 Erythromycin esterase DUF506 PF04720.7 AAS51796.1 - 0.031 13.9 4.0 0.035 13.7 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) HD_4 PF13328.1 AAS51796.1 - 0.056 13.1 1.6 0.081 12.6 1.1 1.3 1 1 0 1 1 1 0 HD domain Nop14 PF04147.7 AAS51796.1 - 0.09 10.6 15.1 0.094 10.6 10.5 1.0 1 0 0 1 1 1 0 Nop14-like family Bd3614_N PF14442.1 AAS51796.1 - 0.091 12.7 4.1 0.12 12.3 2.9 1.1 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Paf1 PF03985.8 AAS51796.1 - 0.32 9.6 11.6 0.33 9.6 8.0 1.1 1 0 0 1 1 1 0 Paf1 DNA_pol_phi PF04931.8 AAS51796.1 - 0.36 8.5 19.2 0.34 8.6 13.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi ANAPC15 PF15243.1 AAS51796.1 - 0.4 10.7 15.7 0.83 9.7 10.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF3381 PF11861.3 AAS51796.1 - 0.41 10.1 13.2 1.6 8.1 8.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) RRN3 PF05327.6 AAS51796.1 - 0.42 8.6 7.3 0.41 8.6 5.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cwf_Cwc_15 PF04889.7 AAS51796.1 - 0.57 9.8 13.6 0.65 9.6 9.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.1 AAS51796.1 - 0.68 9.6 7.9 0.86 9.2 5.5 1.2 1 0 0 1 1 1 0 FAM176 family Tim54 PF11711.3 AAS51796.1 - 0.7 8.4 4.3 0.7 8.4 3.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 AAS51796.1 - 0.92 7.4 11.1 0.94 7.4 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 AAS51796.1 - 0.99 8.4 16.6 1.2 8.2 11.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT GCIP PF13324.1 AAS51796.1 - 1 8.4 6.8 1.1 8.3 4.7 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF1510 PF07423.6 AAS51796.1 - 1.3 8.3 9.7 1.4 8.2 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BTV_NS2 PF04514.7 AAS51796.1 - 1.3 7.7 6.5 1.5 7.5 4.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Rep_4 PF05797.6 AAS51796.1 - 1.3 7.6 5.5 1.5 7.4 3.8 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) HSP90 PF00183.13 AAS51796.1 - 1.5 7.1 11.0 1.5 7.1 7.6 1.1 1 0 0 1 1 1 0 Hsp90 protein SDA1 PF05285.7 AAS51796.1 - 1.6 7.9 14.5 1.6 7.9 10.1 1.1 1 0 0 1 1 1 0 SDA1 Pox_RNA_Pol_19 PF05320.7 AAS51796.1 - 1.9 8.2 10.8 2.9 7.6 7.5 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit IncA PF04156.9 AAS51796.1 - 2.2 7.8 8.4 2.6 7.6 5.8 1.2 1 0 0 1 1 1 0 IncA protein BUD22 PF09073.5 AAS51796.1 - 2.4 7.1 10.3 2.5 7.0 7.1 1.1 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.6 AAS51796.1 - 2.5 5.8 7.1 2.5 5.8 4.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-T PF15511.1 AAS51796.1 - 2.5 7.2 10.8 2.9 7.0 7.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TRAP_alpha PF03896.11 AAS51796.1 - 3.1 6.6 12.1 3.5 6.5 8.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ycf1 PF05758.7 AAS51796.1 - 3.5 5.2 4.5 3.3 5.2 3.1 1.0 1 0 0 1 1 1 0 Ycf1 RXT2_N PF08595.6 AAS51796.1 - 3.7 7.3 10.6 5.4 6.7 7.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Daxx PF03344.10 AAS51796.1 - 3.9 5.8 19.3 3.9 5.8 13.4 1.1 1 0 0 1 1 1 0 Daxx Family VID27 PF08553.5 AAS51796.1 - 4.4 5.3 13.5 5.2 5.1 9.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein LAT PF15234.1 AAS51796.1 - 4.5 6.6 8.4 5.9 6.2 5.8 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells Nop53 PF07767.6 AAS51796.1 - 5.2 5.9 12.8 6.9 5.5 8.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) APG6 PF04111.7 AAS51796.1 - 5.2 6.0 7.9 6.1 5.7 5.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 NOA36 PF06524.7 AAS51796.1 - 6 6.0 14.2 7.7 5.6 9.9 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4637 PF15470.1 AAS51796.1 - 6.1 6.4 11.7 8 6.0 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Adeno_terminal PF02459.10 AAS51796.1 - 6.2 4.8 6.1 6.2 4.8 4.2 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Med17 PF10156.4 AAS51796.1 - 7.1 4.7 10.3 9 4.4 7.2 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex D123 PF07065.9 AAS51796.1 - 7.2 5.5 8.7 8.6 5.3 5.8 1.3 1 1 0 1 1 1 0 D123 Nucleoplasmin PF03066.10 AAS51796.1 - 9 5.8 21.8 13 5.2 15.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin HLH PF00010.21 AAS51797.3 - 1e-14 53.9 0.2 1e-14 53.9 0.2 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CDC45 PF02724.9 AAS51798.1 - 1.9 6.4 8.5 2.6 5.9 5.9 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2360 PF10152.4 AAS51798.1 - 5.8 7.1 9.4 7 6.9 5.2 2.2 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) AF-4 PF05110.8 AAS51798.1 - 6.1 4.5 15.1 9.1 3.9 10.4 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein His_biosynth PF00977.16 AAS51799.1 - 1.8e-23 83.0 0.0 2.1e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein RNA_pol_A_bac PF01000.21 AAS51800.1 - 1.1e-31 109.2 0.2 2.8e-31 107.9 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AAS51800.1 - 1.1e-14 53.2 0.0 1.5e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Tim44 PF04280.10 AAS51802.1 - 8.1e-33 113.4 0.0 1.8e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 Tim44-like domain Spore_III_AB PF09548.5 AAS51802.1 - 0.012 15.4 1.2 0.037 13.7 0.1 2.3 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Ribosomal_S18 PF01084.15 AAS51803.1 - 6.8e-14 51.4 0.1 8.5e-13 47.9 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein S18 BCDHK_Adom3 PF10436.4 AAS51804.1 - 1.2e-23 83.4 0.4 1.9e-23 82.7 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 AAS51804.1 - 5.4e-21 74.3 0.0 9.4e-21 73.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AAS51804.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AAS51804.1 - 0.0094 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain BAR_2 PF10455.4 AAS51805.1 - 2.8e-72 243.0 13.9 2.8e-72 243.0 9.6 1.9 2 1 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 AAS51805.1 - 4.1e-13 49.3 11.2 4.1e-13 49.3 7.8 2.5 1 1 1 2 2 2 1 BAR domain Inhibitor_I24 PF10465.4 AAS51805.1 - 0.088 12.5 0.1 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 PinA peptidase inhibitor DUF3692 PF12469.3 AAS51805.1 - 0.48 10.6 2.8 3 8.1 0.9 2.7 2 1 0 2 2 2 0 CRISPR-associated protein ACCA PF03255.9 AAS51805.1 - 6.1 6.3 9.4 0.47 10.0 0.7 2.9 2 2 2 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Scaffolding_pro PF11418.3 AAS51805.1 - 8.6 6.7 10.0 0.46 10.8 0.1 3.4 3 1 1 4 4 4 0 Phi29 scaffolding protein Ofd1_CTDD PF10637.4 AAS51806.2 - 1.5e-90 302.9 1.0 7.8e-88 294.0 0.8 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 AAS51806.2 - 2.5e-16 59.9 0.2 3.8e-15 56.2 0.1 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Complex1_LYR_1 PF13232.1 AAS51807.1 - 1.3e-14 54.1 1.2 1.8e-14 53.6 0.8 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 AAS51807.1 - 1.1e-12 47.5 1.9 1.6e-12 47.0 1.3 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 AAS51807.1 - 0.058 13.8 2.7 0.075 13.5 1.9 1.2 1 0 0 1 1 1 0 Complex1_LYR-like DnaJ-X PF14308.1 AAS51809.2 - 3.2e-55 186.5 4.4 5e-55 185.9 3.0 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 AAS51809.2 - 4.6e-26 90.3 4.2 1.2e-25 89.0 1.4 2.5 2 0 0 2 2 2 1 DnaJ domain DUF848 PF05852.6 AAS51809.2 - 0.25 11.2 6.1 0.1 12.4 2.0 1.9 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Metallophos PF00149.23 AAS51810.1 - 4.6e-26 91.4 4.4 6.2e-26 91.0 3.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA PF00004.24 AAS51811.2 - 1.8e-38 131.7 0.0 3.1e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AAS51811.2 - 1.2e-05 25.4 0.1 0.00042 20.4 0.1 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AAS51811.2 - 6.5e-05 22.0 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Vps4_C PF09336.5 AAS51811.2 - 0.00012 21.8 0.0 0.00038 20.2 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.9 AAS51811.2 - 0.00042 20.0 0.1 0.0015 18.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AAS51811.2 - 0.00043 20.2 0.0 0.00077 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AAS51811.2 - 0.00058 19.8 0.6 0.0036 17.2 0.1 2.6 2 1 1 3 3 2 1 AAA ATPase domain TIP49 PF06068.8 AAS51811.2 - 0.0008 18.2 0.0 0.0015 17.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 AAS51811.2 - 0.0015 17.9 0.2 0.23 10.8 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AAS51811.2 - 0.0017 18.2 0.0 0.0041 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AAS51811.2 - 0.0019 17.9 0.1 0.027 14.2 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 AAS51811.2 - 0.002 18.4 0.0 0.0056 16.9 0.0 1.7 1 1 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.12 AAS51811.2 - 0.0025 17.2 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 AAS51811.2 - 0.0037 16.4 0.1 0.0074 15.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 AAS51811.2 - 0.0067 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AAS51811.2 - 0.0072 17.1 0.0 0.024 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 AAS51811.2 - 0.0074 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Chromo PF00385.19 AAS51811.2 - 0.015 14.9 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain AAA_14 PF13173.1 AAS51811.2 - 0.015 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AAS51811.2 - 0.017 15.4 0.0 0.08 13.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AAS51811.2 - 0.02 14.8 0.5 0.078 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 AAS51811.2 - 0.052 12.7 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 AAS51811.2 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AAS51811.2 - 0.075 12.7 0.0 0.42 10.2 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase NACHT PF05729.7 AAS51811.2 - 0.14 11.7 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain KaiC PF06745.8 AAS51811.2 - 0.2 10.7 0.1 2.4 7.1 0.0 2.3 1 1 1 2 2 2 0 KaiC Guanylate_kin PF00625.16 AAS51811.2 - 0.3 10.5 1.5 0.61 9.4 0.0 2.2 3 0 0 3 3 3 0 Guanylate kinase Not3 PF04065.10 AAS51812.2 - 1.8e-91 305.5 22.4 1.8e-91 305.5 15.5 1.8 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 AAS51812.2 - 8.8e-30 103.3 0.2 8.8e-30 103.3 0.1 2.1 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.1 AAS51812.2 - 0.11 12.5 6.2 0.028 14.4 1.1 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Ribosomal_S18 PF01084.15 AAS51812.2 - 0.83 9.5 3.7 0.61 9.9 0.7 2.1 2 0 0 2 2 2 0 Ribosomal protein S18 DUF4476 PF14771.1 AAS51815.2 - 0.034 14.1 0.1 1 9.4 0.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4476) KOW PF00467.24 AAS51815.2 - 0.07 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 KOW motif bZIP_1 PF00170.16 AAS51816.2 - 7.3e-15 54.6 8.5 1e-14 54.2 5.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AAS51816.2 - 4.4e-07 29.6 8.3 7.6e-07 28.8 5.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 AAS51816.2 - 0.0075 16.5 3.9 0.013 15.7 2.7 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF1313 PF07011.6 AAS51816.2 - 0.1 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1313) DUF733 PF05306.6 AAS51816.2 - 0.45 10.8 3.5 0.75 10.1 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF733) Pkinase PF00069.20 AAS51818.1 - 4.4e-57 193.1 4.2 9.9e-57 192.0 2.9 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51818.1 - 1.2e-18 67.0 2.6 1.1e-13 50.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 AAS51818.1 - 7.5e-07 29.1 0.1 2.9e-05 23.9 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AAS51818.1 - 0.0056 16.2 0.4 0.022 14.3 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 AAS51818.1 - 0.039 13.0 0.1 0.081 11.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AAS51818.1 - 0.061 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.4 AAS51818.1 - 0.17 11.2 1.1 2.7 7.2 0.0 2.8 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL DUF496 PF04363.7 AAS51818.1 - 0.22 11.3 4.3 0.26 11.1 0.5 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF496) F_actin_cap_B PF01115.12 AAS51819.1 - 1.5e-93 312.4 0.0 1.8e-93 312.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Erg28 PF03694.8 AAS51820.1 - 2.8e-45 152.8 0.5 3.5e-45 152.5 0.4 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF4293 PF14126.1 AAS51820.1 - 0.032 14.1 0.5 0.04 13.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Fzo_mitofusin PF04799.8 AAS51820.1 - 0.068 12.5 0.1 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF2416 PF10315.4 AAS51820.1 - 0.093 12.9 1.0 1.9 8.7 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2416) cNMP_binding PF00027.24 AAS51821.1 - 5.1e-43 144.7 0.2 6.2e-23 80.4 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 AAS51821.1 - 2.3e-09 36.5 2.7 6.5e-09 35.0 1.8 1.8 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit SNF2_N PF00176.18 AAS51822.1 - 1.6e-68 230.7 0.1 3e-68 229.8 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AAS51822.1 - 2.8e-15 55.9 0.0 1.9e-14 53.2 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS51822.1 - 2.2e-08 34.1 0.0 7.8e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AAS51822.1 - 0.0001 21.8 0.0 0.00024 20.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AAS51822.1 - 0.011 15.8 0.2 0.075 13.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain E7 PF00527.13 AAS51822.1 - 0.056 13.6 0.5 0.44 10.7 0.0 2.7 2 0 0 2 2 2 0 E7 protein, Early protein SWIRM PF04433.12 AAS51823.2 - 7.3e-32 109.3 0.2 1.5e-31 108.3 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 AAS51823.2 - 1e-11 44.1 3.3 1.6e-11 43.5 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 AAS51823.2 - 1.1e-06 28.5 0.1 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AAS51823.2 - 1.8e-06 27.9 0.0 8.2e-06 25.8 0.0 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Elf1 PF05129.8 AAS51823.2 - 0.11 12.1 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like KfrA_N PF11740.3 AAS51823.2 - 0.74 10.2 10.6 3.7 8.0 0.2 4.0 4 0 0 4 4 4 0 Plasmid replication region DNA-binding N-term DUF4337 PF14235.1 AAS51823.2 - 1.2 8.8 4.0 14 5.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) THOC7 PF05615.8 AAS51823.2 - 1.5 9.0 9.6 0.14 12.4 1.7 2.6 3 0 0 3 3 3 0 Tho complex subunit 7 Zip PF02535.17 AAS51824.1 - 2.9e-49 167.8 14.1 8e-47 159.7 9.8 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter MFS_1 PF07690.11 AAS51825.2 - 4.2e-29 101.3 59.6 1.6e-27 96.1 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AAS51825.2 - 0.042 12.4 48.5 22 3.4 33.7 3.2 1 1 0 1 1 1 0 Sugar (and other) transporter MFS_1_like PF12832.2 AAS51825.2 - 0.05 13.4 0.4 0.05 13.4 0.2 3.9 5 0 0 5 5 5 0 MFS_1 like family STAG PF08514.6 AAS51827.2 - 9.7e-09 34.9 2.4 7.9e-08 32.0 0.2 3.2 3 0 0 3 3 3 1 STAG domain HEAT PF02985.17 AAS51827.2 - 9e-05 22.2 0.3 0.15 12.2 0.0 4.3 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 AAS51827.2 - 0.06 13.6 0.0 0.91 9.8 0.0 2.8 2 1 1 3 3 3 0 HEAT repeats MMgT PF10270.4 AAS51828.1 - 4.8e-28 97.6 0.0 5.6e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter APC_CDC26 PF10471.4 AAS51829.1 - 1.8e-23 83.0 0.5 2.4e-23 82.6 0.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 RINGv PF12906.2 AAS51830.1 - 3.5e-14 52.5 6.8 7.4e-14 51.5 4.7 1.6 1 0 0 1 1 1 1 RING-variant domain Peptidase_C48 PF02902.14 AAS51831.2 - 5e-38 130.8 3.3 8.1e-38 130.2 2.3 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4441 PF14536.1 AAS51831.2 - 1.7 8.6 7.8 2.3 8.2 1.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4441) Cupin_8 PF13621.1 AAS51832.2 - 5e-06 26.2 0.0 0.00011 21.7 0.0 2.3 1 1 0 1 1 1 1 Cupin-like domain PHD PF00628.24 AAS51832.2 - 5.1e-05 22.8 7.1 9.9e-05 21.9 4.9 1.5 1 0 0 1 1 1 1 PHD-finger Cupin_1 PF00190.17 AAS51832.2 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_4 PF08007.7 AAS51832.2 - 0.0086 15.3 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 AAS51832.2 - 0.02 15.1 0.0 11 6.2 0.0 2.8 3 0 0 3 3 3 0 JmjC domain, hydroxylase C1_1 PF00130.17 AAS51832.2 - 0.029 14.0 7.9 0.055 13.2 5.5 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cupin_2 PF07883.6 AAS51832.2 - 0.043 13.3 0.4 0.35 10.4 0.0 2.6 4 0 0 4 4 4 0 Cupin domain zf-HC5HC2H PF13771.1 AAS51832.2 - 0.1 12.7 3.0 0.28 11.3 2.1 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain NAD_binding_1 PF00175.16 AAS51833.1 - 7.6e-30 103.6 0.0 1.3e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AAS51833.1 - 1.1e-26 92.8 0.0 1.7e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AAS51833.1 - 3.8e-05 23.6 0.0 0.0076 16.1 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 AAS51833.1 - 0.094 12.6 0.0 0.23 11.4 0.0 1.8 1 1 1 2 2 2 0 Siderophore-interacting FAD-binding domain AA_kinase PF00696.23 AAS51834.1 - 7.8e-42 143.4 0.0 1.5e-41 142.5 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 AAS51834.1 - 3.1e-14 52.0 0.4 1.5e-07 30.7 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 AAS51834.1 - 2.2e-08 33.4 5.3 1.9e-06 27.2 0.3 3.2 3 0 0 3 3 3 2 ACT domain Fe-ADH_2 PF13685.1 AAS51834.1 - 0.87 8.8 4.7 2.9 7.1 0.1 2.8 3 0 0 3 3 3 0 Iron-containing alcohol dehydrogenase Cyt-b5 PF00173.23 AAS51835.1 - 1.3e-20 72.9 0.0 2.2e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2269 PF10027.4 AAS51835.1 - 0.0069 16.1 0.1 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) DUF3753 PF12575.3 AAS51835.1 - 0.15 11.8 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) ArfGap PF01412.13 AAS51836.1 - 1.9e-35 121.1 0.3 2.7e-35 120.6 0.2 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CBM_21 PF03370.8 AAS51837.2 - 5.1e-31 106.9 0.1 8.5e-31 106.2 0.1 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Glu_cyclase_2 PF05096.7 AAS51837.2 - 0.04 12.9 0.1 0.097 11.6 0.0 1.5 1 1 0 1 1 1 0 Glutamine cyclotransferase CBM_25 PF03423.8 AAS51837.2 - 6.1 7.0 7.7 10 6.2 3.7 2.5 2 1 0 2 2 2 0 Carbohydrate binding domain (family 25) WD40 PF00400.27 AAS51838.2 - 1.2e-50 167.6 28.0 5.5e-11 41.8 0.6 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 AAS51838.2 - 2.4e-15 55.9 0.4 5.3e-15 54.8 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AAS51838.2 - 1.4e-09 37.3 0.0 4.8e-09 35.6 0.0 2.0 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 AAS51838.2 - 3.4e-09 35.4 15.7 0.0042 15.2 0.1 5.9 1 1 5 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AAS51838.2 - 0.005 15.6 1.0 3.1 6.4 0.5 3.5 2 1 1 3 3 3 1 Nup133 N terminal like HisG PF01634.13 AAS51839.1 - 1.3e-51 174.4 0.0 2e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 AAS51839.1 - 6.4e-28 96.5 0.0 1.1e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain EXS PF03124.9 AAS51840.2 - 2.8e-92 309.4 26.5 4e-92 308.8 18.4 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 AAS51840.2 - 1.1e-43 150.0 0.4 1.1e-43 150.0 0.3 1.6 2 0 0 2 2 2 1 SPX domain Nucleoplasmin PF03066.10 AAS51840.2 - 0.15 11.5 2.5 0.29 10.6 1.1 1.8 2 0 0 2 2 2 0 Nucleoplasmin E1-E2_ATPase PF00122.15 AAS51841.1 - 1.4e-27 96.2 0.1 3.1e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AAS51841.1 - 3.1e-14 53.9 0.0 1e-13 52.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AAS51841.1 - 1.6e-09 38.2 0.8 9.9e-09 35.6 0.6 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AAS51841.1 - 5e-08 32.8 0.0 2.4e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AAS51841.1 - 0.0055 16.3 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_L34e PF01199.13 AAS51842.2 - 3.5e-37 126.4 4.5 3.5e-37 126.4 3.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e EndIII_4Fe-2S PF10576.4 AAS51842.2 - 0.39 10.9 0.1 0.39 10.9 0.1 2.2 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Ribonuc_L-PSP PF01042.16 AAS51843.1 - 6.3e-40 135.7 0.3 7.6e-40 135.4 0.2 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Cyclin PF08613.6 AAS51845.1 - 1e-44 152.5 0.6 1.3e-44 152.1 0.4 1.1 1 0 0 1 1 1 1 Cyclin Transp_cyt_pur PF02133.10 AAS51846.1 - 1.3e-70 238.1 40.2 1.6e-70 237.8 27.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Steroid_dh PF02544.11 AAS51847.1 - 5e-13 49.0 2.0 5e-13 49.0 1.4 2.0 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF998 PF06197.8 AAS51847.1 - 0.016 14.5 0.7 0.016 14.5 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF998) ketoacyl-synt PF00109.21 AAS51848.1 - 1e-52 179.1 5.9 1.5e-52 178.6 0.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 AAS51848.1 - 9.6e-33 112.5 1.6 1.8e-32 111.6 1.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 AAS51848.1 - 0.0028 16.6 0.1 0.0064 15.5 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain HAD_2 PF13419.1 AAS51849.1 - 1.1e-10 42.0 0.0 1.5e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AAS51849.1 - 7.4e-08 33.0 0.0 3.3e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AAS51849.1 - 1.1e-07 31.5 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like SAP PF02037.22 AAS51851.1 - 2e-14 52.6 0.4 5.9e-14 51.1 0.1 1.9 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 AAS51851.1 - 0.017 14.6 0.2 0.052 13.1 0.1 1.9 1 1 0 1 1 1 0 HeH/LEM domain DUF2360 PF10152.4 AAS51851.1 - 0.19 12.0 9.4 0.27 11.5 6.5 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Vhr1 PF04001.8 AAS51853.2 - 1.4e-49 165.8 1.4 3.2e-49 164.7 1.0 1.6 1 0 0 1 1 1 1 Transcription factor Vhr1 ICL PF00463.16 AAS51854.1 - 3.2e-265 880.3 0.0 3.6e-265 880.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 AAS51854.1 - 1.2e-09 37.7 0.1 2.6e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF2578 PF10843.3 AAS51855.2 - 1e-63 214.5 14.8 1.2e-63 214.2 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) Pkip-1 PF06878.6 AAS51855.2 - 0.15 11.9 0.3 0.15 11.9 0.2 1.8 2 0 0 2 2 2 0 Pkip-1 protein zf-RING_4 PF14570.1 AAS51856.1 - 6.6e-20 70.4 13.5 1.3e-19 69.5 9.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 AAS51856.1 - 5e-09 35.8 0.2 1.1e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AAS51856.1 - 3.3e-08 33.0 0.0 6.3e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 AAS51856.1 - 5.1e-06 26.2 3.3 1.1e-05 25.1 2.3 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_6 PF14259.1 AAS51856.1 - 8.8e-06 25.6 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 AAS51856.1 - 1.1e-05 24.9 7.1 1.1e-05 24.9 4.9 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AAS51856.1 - 0.00049 19.8 8.9 0.0012 18.6 6.2 1.7 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 AAS51856.1 - 0.0005 19.3 2.2 0.0005 19.3 1.5 2.2 2 0 0 2 2 2 1 Rtf2 RING-finger SET_assoc PF11767.3 AAS51856.1 - 0.003 16.8 0.1 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated zf-C3HC4 PF00097.20 AAS51856.1 - 0.005 16.4 11.0 0.011 15.4 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 AAS51856.1 - 0.068 12.9 4.1 0.2 11.4 2.8 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger PocR PF10114.4 AAS51856.1 - 0.086 11.9 2.1 0.17 11.0 0.4 2.1 2 0 0 2 2 2 0 Sensory domain found in PocR zf-RING_5 PF14634.1 AAS51856.1 - 0.11 12.2 9.7 0.22 11.2 6.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Peptidase_S49_N PF08496.5 AAS51856.1 - 0.62 9.8 4.2 0.21 11.3 0.2 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal zf-C3HC4_4 PF15227.1 AAS51856.1 - 2.1 8.3 11.1 9.1 6.2 7.7 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING U1snRNP70_N PF12220.3 AAS51857.1 - 1.3e-25 89.5 1.1 2.1e-25 88.8 0.7 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 AAS51857.1 - 2.6e-16 59.0 0.0 5.4e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS51857.1 - 2.9e-15 55.9 0.0 5.4e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS51857.1 - 1.2e-06 28.2 0.0 2.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF619 PF04768.8 AAS51858.2 - 4.2e-50 169.4 0.0 1.1e-49 168.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 AAS51858.2 - 1.6e-27 96.1 0.0 3.5e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 AAS51858.2 - 3.8e-21 75.7 0.0 6.9e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 AAS51858.2 - 0.0028 17.5 0.0 0.0073 16.2 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus P16-Arc PF04699.9 AAS51859.1 - 1.5e-51 174.4 0.0 1.7e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Ran_BP1 PF00638.13 AAS51860.2 - 4.3e-29 101.0 0.0 8.1e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Methyltransf_31 PF13847.1 AAS51861.2 - 4.2e-21 75.1 0.0 5.5e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS51861.2 - 9.7e-18 64.7 0.2 1.5e-17 64.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AAS51861.2 - 1.9e-11 44.3 0.1 3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AAS51861.2 - 1.2e-10 41.4 2.4 2.4e-10 40.4 1.7 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AAS51861.2 - 2.7e-09 36.9 0.0 5.9e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AAS51861.2 - 3.4e-09 36.2 0.0 7.3e-09 35.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 AAS51861.2 - 1.1e-08 35.4 0.0 1.7e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AAS51861.2 - 1.8e-08 34.6 0.1 3.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 AAS51861.2 - 1.1e-05 25.1 0.0 2e-05 24.3 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 AAS51861.2 - 3.1e-05 23.4 0.0 5.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.6 AAS51861.2 - 0.00012 21.5 0.0 0.00048 19.6 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.9 AAS51861.2 - 0.0024 17.0 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.15 AAS51861.2 - 0.0031 16.6 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.8 AAS51861.2 - 0.0034 17.4 0.2 0.0056 16.7 0.1 1.4 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_4 PF02390.12 AAS51861.2 - 0.0079 15.2 0.0 0.015 14.3 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.8 AAS51861.2 - 0.024 13.7 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 AAS51861.2 - 0.025 13.7 0.0 0.051 12.6 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 AAS51861.2 - 0.033 13.7 0.0 0.05 13.1 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 AAS51861.2 - 0.087 11.5 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) FmrO PF07091.6 AAS51861.2 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Fis1_TPR_C PF14853.1 AAS51862.1 - 3.9e-24 84.2 1.1 5.9e-24 83.7 0.8 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 AAS51862.1 - 7.2e-17 60.3 0.0 1.3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.1 AAS51862.1 - 4.5e-05 23.7 0.7 0.00012 22.3 0.5 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 AAS51862.1 - 8.8e-05 22.1 1.2 0.00018 21.1 0.8 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 AAS51862.1 - 0.00026 21.3 0.4 0.00026 21.3 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 AAS51862.1 - 0.017 15.3 0.1 0.026 14.7 0.1 1.3 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation TPR_17 PF13431.1 AAS51862.1 - 0.021 14.9 0.3 13 6.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 AAS51862.1 - 0.036 14.2 0.2 0.053 13.6 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AAS51862.1 - 0.057 13.2 0.2 0.057 13.2 0.2 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 AAS51862.1 - 0.32 11.7 7.1 1.2 9.9 4.9 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Ribonuc_red_lgC PF02867.10 AAS51863.2 - 2.5e-218 726.0 0.0 3.4e-218 725.5 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 AAS51863.2 - 7.4e-25 86.5 0.1 4.2e-24 84.1 0.0 2.3 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 AAS51863.2 - 8e-17 61.4 0.2 4.8e-16 58.9 0.0 2.5 3 0 0 3 3 3 1 ATP cone domain NRDD PF13597.1 AAS51863.2 - 0.0019 16.3 0.0 0.003 15.6 0.0 1.2 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase PUF PF00806.14 AAS51864.2 - 7.3e-56 182.6 33.8 2.3e-08 33.0 1.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat PAT1 PF09770.4 AAS51864.2 - 4 5.5 37.3 7.6 4.6 25.8 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HECT PF00632.20 AAS51865.1 - 4.6e-91 305.2 0.0 6.2e-91 304.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 AAS51865.1 - 3.4e-34 116.3 22.6 2.7e-11 43.1 2.6 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 AAS51865.1 - 1.5e-16 60.0 0.2 3.5e-16 58.8 0.1 1.6 1 0 0 1 1 1 1 C2 domain TRH PF05438.7 AAS51865.1 - 0.081 12.3 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) WD40 PF00400.27 AAS51866.1 - 0.00025 20.7 2.3 0.0013 18.5 0.1 3.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AAS51866.1 - 0.0065 15.2 0.2 0.0097 14.6 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.20 AAS51867.1 - 1.7e-28 99.4 0.0 2.6e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51867.1 - 3.4e-10 39.4 0.0 4.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AAS51867.1 - 0.046 13.4 0.0 0.95 9.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_M44 PF03410.8 AAS51867.1 - 0.1 10.8 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein G1 Zip PF02535.17 AAS51867.1 - 9.4 5.1 6.1 14 4.6 4.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MRG PF05712.8 AAS51868.1 - 3.1e-50 169.8 0.0 4.2e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 AAS51868.1 - 1.2e-06 28.0 0.2 2.5e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-C2H2 PF00096.21 AAS51869.1 - 3.2e-11 42.8 10.6 2.1e-05 24.5 1.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS51869.1 - 1.7e-08 34.1 9.2 0.00048 20.2 0.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AAS51869.1 - 4.3e-07 29.9 13.4 3.8e-06 26.9 0.8 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 AAS51869.1 - 2.1e-05 24.5 5.2 0.00037 20.6 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type C1_4 PF07975.7 AAS51869.1 - 0.0032 17.4 2.3 0.0058 16.6 1.6 1.5 1 0 0 1 1 1 1 TFIIH C1-like domain zf-C2H2_6 PF13912.1 AAS51869.1 - 0.0076 16.1 2.3 0.18 11.7 0.5 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AAS51869.1 - 0.01 15.9 1.5 0.11 12.6 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 AAS51869.1 - 0.23 11.6 3.2 0.3 11.2 1.4 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 AAS51869.1 - 6.2 6.6 10.5 0.99 9.2 1.3 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2 PF00096.21 AAS51870.1 - 1.2e-10 41.1 6.8 4e-05 23.7 0.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS51870.1 - 1.8e-08 34.1 6.6 0.0003 20.8 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AAS51870.1 - 1.6e-05 24.9 10.6 0.12 12.7 0.0 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-met PF12874.2 AAS51870.1 - 1.6e-05 24.8 5.8 0.0031 17.6 0.2 2.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-BED PF02892.10 AAS51870.1 - 0.018 14.8 5.8 1.5 8.6 0.1 2.2 2 0 0 2 2 2 0 BED zinc finger DUF2256 PF10013.4 AAS51870.1 - 0.038 13.7 0.3 0.083 12.6 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_6 PF13912.1 AAS51870.1 - 0.079 12.8 0.7 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 AAS51870.1 - 0.22 11.6 2.4 0.65 10.1 1.7 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 AAS51870.1 - 1.4 9.0 4.8 5.2 7.2 0.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Mito_carr PF00153.22 AAS51871.1 - 9.9e-74 243.1 0.1 4.2e-25 87.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 AAS51871.1 - 0.064 13.3 6.2 0.63 10.2 0.7 4.1 3 1 0 3 3 3 0 EF-hand domain pair ORF6N PF10543.4 AAS51872.1 - 0.13 12.2 0.9 1.2 9.2 0.2 2.3 2 0 0 2 2 2 0 ORF6N domain Bud13 PF09736.4 AAS51873.1 - 6.8e-28 97.7 4.7 6.8e-28 97.7 3.3 3.1 2 2 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex AAA_28 PF13521.1 AAS51873.1 - 0.033 14.1 0.4 0.052 13.5 0.3 1.4 1 0 0 1 1 1 0 AAA domain XRN_N PF03159.13 AAS51874.1 - 3.2e-96 321.2 0.2 3.2e-96 321.2 0.1 1.8 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Nucleoporin_FG PF13634.1 AAS51875.1 - 1.3e-09 38.2 132.4 4.7e-05 23.5 28.5 3.5 2 1 2 4 4 4 3 Nucleoporin FG repeat region DUF1664 PF07889.7 AAS51875.1 - 0.13 12.0 2.1 0.53 10.0 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Pkinase PF00069.20 AAS51877.1 - 6.6e-49 166.3 0.0 1.9e-48 164.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51877.1 - 3.8e-19 68.7 0.0 1.1e-18 67.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS51877.1 - 0.056 12.3 0.0 0.15 10.9 0.0 1.8 2 1 0 2 2 2 0 Kinase-like zf-C2H2 PF00096.21 AAS51878.1 - 1.8e-09 37.3 15.6 5.6e-06 26.3 0.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS51878.1 - 4.3e-07 29.7 11.4 0.00051 20.1 0.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AAS51878.1 - 5.3e-07 29.6 12.3 0.00041 20.5 0.5 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AAS51878.1 - 6.3e-05 22.9 1.3 0.0042 17.1 0.0 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AAS51878.1 - 0.0001 22.3 1.8 0.0092 16.1 0.0 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-BED PF02892.10 AAS51878.1 - 0.0036 17.0 5.4 0.033 13.9 0.3 2.7 1 1 1 2 2 2 1 BED zinc finger zf-C2H2_6 PF13912.1 AAS51878.1 - 0.015 15.2 1.7 1.5 8.8 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 AAS51878.1 - 0.33 11.0 4.4 1.1 9.3 0.2 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CHCH PF06747.8 AAS51879.2 - 0.0048 16.7 2.8 0.017 14.9 1.9 1.8 1 1 1 2 2 2 2 CHCH domain Cmc1 PF08583.5 AAS51879.2 - 0.03 14.1 0.7 0.037 13.8 0.5 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 AAS51879.2 - 0.12 12.3 2.9 0.73 9.9 2.0 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 zf-C2H2 PF00096.21 AAS51880.2 - 1.4e-08 34.5 9.6 0.0006 20.0 1.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS51880.2 - 0.00015 21.8 8.9 0.081 13.3 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AAS51880.2 - 0.00021 21.4 0.1 0.00021 21.4 0.1 3.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AAS51880.2 - 0.0024 17.9 3.5 0.16 12.1 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AAS51880.2 - 0.0072 16.5 6.5 0.04 14.1 0.2 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 AAS51880.2 - 1.3 9.4 5.1 9.7 6.6 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 AAS51880.2 - 2.2 8.4 6.3 2.3 8.3 0.3 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) tRNA-synt_2 PF00152.15 AAS51881.1 - 3.7e-84 282.3 2.1 3.7e-84 282.3 1.5 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AAS51881.1 - 1.8e-06 27.6 0.1 4.3e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AAS51881.1 - 0.053 12.6 1.8 1.1 8.4 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) RasGEF PF00617.14 AAS51882.2 - 1.1e-58 198.1 0.3 3.5e-58 196.4 0.0 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 AAS51882.2 - 8e-22 77.3 0.1 2.7e-21 75.6 0.1 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 AAS51882.2 - 2.7e-09 36.4 0.0 5.5e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AAS51882.2 - 7.5e-08 31.6 0.0 3.5e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AAS51882.2 - 1.4e-07 30.8 0.0 4e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain GRIP PF01465.15 AAS51883.2 - 2.1e-16 59.1 0.3 1.4e-15 56.4 0.2 2.5 2 0 0 2 2 2 1 GRIP domain CALCOCO1 PF07888.6 AAS51883.2 - 0.00041 18.7 24.6 0.00041 18.7 17.0 4.9 1 1 3 4 4 4 3 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.4 AAS51883.2 - 0.00051 19.9 19.2 0.00051 19.9 13.3 8.0 3 3 4 7 7 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 AAS51883.2 - 0.07 10.8 131.7 0.087 10.5 23.9 4.2 2 2 1 3 3 3 0 Myosin tail Spc7 PF08317.6 AAS51883.2 - 0.34 9.5 114.2 0.086 11.4 15.7 6.7 2 1 3 6 6 6 0 Spc7 kinetochore protein IncA PF04156.9 AAS51883.2 - 1.2 8.6 143.1 0.48 9.9 11.5 7.4 2 2 4 8 8 8 0 IncA protein TPR_MLP1_2 PF07926.7 AAS51883.2 - 4.5 7.0 136.5 0.012 15.3 7.6 7.9 4 2 3 7 7 7 0 TPR/MLP1/MLP2-like protein Polysacc_deac_1 PF01522.16 AAS51884.1 - 4.9e-24 84.3 0.0 7.6e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF3436 PF11918.3 AAS51884.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3436) UQ_con PF00179.21 AAS51886.1 - 3e-32 110.9 0.0 3.9e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PI3_PI4_kinase PF00454.22 AAS51888.1 - 3e-43 147.9 0.0 9.5e-43 146.3 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 AAS51888.1 - 4.6e-25 87.8 0.2 1.2e-24 86.4 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Aconitase PF00330.15 AAS51889.1 - 8.9e-179 594.8 0.0 1.6e-178 593.9 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AAS51889.1 - 8.5e-47 158.5 0.0 1.8e-46 157.5 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Como_SCP PF02248.11 AAS51889.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Small coat protein Cys_Met_Meta_PP PF01053.15 AAS51890.2 - 2.2e-141 470.6 0.0 2.5e-141 470.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 AAS51890.2 - 1.6e-09 37.3 0.4 4.4e-09 35.8 0.1 1.8 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 AAS51890.2 - 2.2e-09 36.7 0.0 3.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 AAS51890.2 - 6.9e-07 28.3 0.0 1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AAS51890.2 - 1.8e-05 24.0 0.0 5.6e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 AAS51890.2 - 2.4e-05 22.8 0.0 4.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase SelA PF03841.8 AAS51890.2 - 0.024 13.3 0.1 0.087 11.5 0.0 1.8 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase GDC-P PF02347.11 AAS51890.2 - 0.04 12.6 0.0 0.059 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein eIF-6 PF01912.13 AAS51891.1 - 7.1e-85 283.1 1.1 8.9e-85 282.7 0.8 1.1 1 0 0 1 1 1 1 eIF-6 family CAF1A PF12253.3 AAS51893.2 - 2e-23 82.2 13.5 2e-23 82.2 9.3 3.8 3 1 1 4 4 4 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 AAS51893.2 - 1.2e-18 67.2 67.1 2.7e-18 66.1 46.5 1.6 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Daxx PF03344.10 AAS51893.2 - 0.82 8.0 42.1 0.24 9.8 2.0 2.2 2 0 0 2 2 2 0 Daxx Family Exonuc_VII_L PF02601.10 AAS51893.2 - 1.5 7.9 19.9 2.3 7.3 13.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Borrelia_P83 PF05262.6 AAS51893.2 - 1.8 6.7 35.5 2.6 6.1 24.6 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF342 PF03961.8 AAS51893.2 - 8.4 4.6 25.6 18 3.6 17.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4231 PF14015.1 AAS51894.1 - 0.24 11.4 0.1 0.24 11.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) MCM PF00493.18 AAS51895.2 - 5.3e-139 462.6 0.1 7.4e-139 462.1 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AAS51895.2 - 1.7e-24 86.5 0.7 1.7e-24 86.5 0.5 2.7 4 0 0 4 4 4 1 MCM N-terminal domain Mg_chelatase PF01078.16 AAS51895.2 - 7.3e-06 25.2 0.0 0.00035 19.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AAS51895.2 - 8.2e-06 25.5 0.0 3.3e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AAS51895.2 - 0.00096 18.7 0.0 0.01 15.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AAS51895.2 - 0.087 12.2 0.2 3.3 7.1 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain ATP-synt_G PF04718.10 AAS51896.1 - 2.9e-30 104.9 0.1 3.4e-30 104.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit DEAD PF00270.24 AAS51897.1 - 1e-43 148.7 0.8 3e-43 147.2 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS51897.1 - 9.6e-27 92.6 0.1 4e-26 90.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS51897.1 - 2e-06 27.7 0.6 5.3e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ribonucleas_3_3 PF14622.1 AAS51898.1 - 1.7e-16 60.3 0.0 2.8e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like GIT_SHD PF08518.6 AAS51899.2 - 2e-22 78.1 9.0 1.8e-12 46.3 0.2 3.0 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT IncA PF04156.9 AAS51899.2 - 1.4 8.4 37.5 1.2 8.7 12.7 3.6 1 1 2 3 3 3 0 IncA protein SlyX PF04102.7 AAS51899.2 - 7.4 7.0 16.2 0.27 11.6 3.5 3.7 2 1 1 3 3 3 0 SlyX Glyco_hydro_72 PF03198.9 AAS51900.2 - 5.2e-136 452.7 3.9 6.4e-136 452.4 2.7 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 AAS51900.2 - 3.8e-05 22.7 0.0 0.0001 21.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 AAS51900.2 - 0.0025 17.0 0.8 0.013 14.7 0.3 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) WSC PF01822.14 AAS51901.2 - 7.1e-10 38.6 8.5 1.7e-09 37.4 5.9 1.6 1 0 0 1 1 1 1 WSC domain Podoplanin PF05808.6 AAS51901.2 - 8e-06 25.5 3.9 1.3e-05 24.8 2.7 1.3 1 0 0 1 1 1 1 Podoplanin Syndecan PF01034.15 AAS51901.2 - 0.0021 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Mid2 PF04478.7 AAS51901.2 - 0.023 14.0 0.1 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.1 AAS51901.2 - 0.05 13.9 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 AAS51901.2 - 0.051 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SLAC1 PF03595.12 AAS51901.2 - 0.057 12.0 0.0 4.8 5.7 0.0 2.1 2 0 0 2 2 2 0 Voltage-dependent anion channel Glycophorin_A PF01102.13 AAS51901.2 - 0.16 11.7 10.3 1.5 8.6 7.1 2.4 1 1 0 1 1 1 0 Glycophorin A DUF2408 PF10303.4 AAS51902.2 - 6.1e-70 233.5 0.7 3e-46 156.8 0.0 4.5 3 2 2 5 5 5 3 Protein of unknown function (DUF2408) TnpV PF14198.1 AAS51902.2 - 0.016 15.0 1.3 0.12 12.2 0.3 2.6 3 0 0 3 3 3 0 Transposon-encoded protein TnpV AhpC-TSA PF00578.16 AAS51903.1 - 3.8e-31 107.3 0.0 5.5e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AAS51903.1 - 3.2e-20 72.1 0.1 4.7e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 AAS51903.1 - 0.00015 21.6 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF1644 PF07800.7 AAS51903.1 - 0.063 13.1 0.2 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) Adap_comp_sub PF00928.16 AAS51904.1 - 3.6e-88 295.0 0.0 4.9e-88 294.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AAS51904.1 - 3.6e-07 29.9 2.3 7.1e-07 29.0 1.2 1.7 1 1 1 2 2 2 1 Clathrin adaptor complex small chain TPP1 PF10341.4 AAS51905.1 - 5.6e-22 77.7 0.0 8.8e-22 77.1 0.0 1.3 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD HMGL-like PF00682.14 AAS51906.1 - 1.1e-65 221.6 0.0 1.8e-65 220.9 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 AAS51906.1 - 3.4e-24 85.1 0.0 1.5e-23 83.0 0.0 2.1 3 0 0 3 3 3 1 LeuA allosteric (dimerisation) domain F-box-like_2 PF13013.1 AAS51906.1 - 0.053 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain Urm1 PF09138.6 AAS51907.1 - 5.1e-37 125.8 0.6 5.7e-37 125.7 0.4 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 AAS51907.1 - 0.0042 17.4 0.0 0.0052 17.1 0.0 1.2 1 0 0 1 1 1 1 ThiS family RE_XcyI PF09571.5 AAS51907.1 - 0.015 14.1 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 XcyI restriction endonuclease YchF-GTPase_C PF06071.8 AAS51907.1 - 0.024 14.4 0.1 0.14 11.9 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF933) PDZ_2 PF13180.1 AAS51908.1 - 1.7e-06 27.8 0.1 3.6e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 AAS51908.1 - 1.5e-05 25.0 0.1 2.3e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) FAA_hydrolase_N PF09298.6 AAS51908.1 - 0.058 13.3 0.1 0.91 9.5 0.0 2.4 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal bZIP_1 PF00170.16 AAS51909.2 - 3.1e-15 55.8 8.8 6.1e-15 54.9 6.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AAS51909.2 - 1.8e-11 43.6 11.4 3.4e-11 42.8 7.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 AAS51909.2 - 0.0018 18.5 3.2 0.0036 17.5 2.2 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF904 PF06005.7 AAS51909.2 - 0.026 14.7 1.8 0.049 13.9 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 AAS51909.2 - 0.027 14.8 0.6 0.057 13.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 AAS51909.2 - 0.051 13.0 1.5 0.087 12.3 1.0 1.4 1 0 0 1 1 1 0 Septum formation initiator TSC22 PF01166.13 AAS51909.2 - 0.082 12.8 0.9 0.17 11.8 0.6 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family HALZ PF02183.13 AAS51909.2 - 0.084 12.6 1.4 0.19 11.4 0.9 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper FTA4 PF13093.1 AAS51909.2 - 0.15 11.4 3.8 0.39 10.1 2.6 1.6 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Cas_Csy4 PF09618.5 AAS51909.2 - 0.21 11.3 1.3 0.36 10.6 0.9 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) RseA_C PF03873.8 AAS51909.2 - 1.4 8.8 4.3 2.9 7.8 0.1 2.9 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain DUF1049 PF06305.6 AAS51910.2 - 0.18 11.3 0.2 0.3 10.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Gti1_Pac2 PF09729.4 AAS51911.1 - 7.7e-56 188.5 0.0 7.7e-56 188.5 0.0 2.2 2 1 0 2 2 2 1 Gti1/Pac2 family Mito_carr PF00153.22 AAS51912.1 - 3.4e-69 228.6 0.9 3.1e-25 87.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Thioredoxin PF00085.15 AAS51913.1 - 7.4e-17 60.9 0.2 5.6e-16 58.1 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin LDB19 PF13002.2 AAS51913.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Arrestin_N terminal like BLYB PF05289.6 AAS51913.1 - 0.069 12.9 0.1 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein Thioredoxin_4 PF13462.1 AAS51913.1 - 0.16 12.0 1.1 1.2 9.1 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin SNARE PF05739.14 AAS51914.1 - 4.7e-07 29.4 0.2 6.8e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.16 AAS51914.1 - 0.002 17.6 0.8 0.0035 16.8 0.5 1.4 1 1 0 1 1 1 1 Synaptobrevin Sec20 PF03908.8 AAS51914.1 - 0.0083 15.8 1.2 0.031 13.9 0.1 1.9 1 1 1 2 2 2 1 Sec20 UPF0197 PF05251.7 AAS51914.1 - 0.28 11.5 3.6 0.69 10.2 2.5 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) ParA PF10609.4 AAS51915.1 - 9.8e-38 127.9 0.1 1.5e-36 124.0 0.0 2.3 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 AAS51915.1 - 2.4e-18 66.2 0.0 3.9e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 AAS51915.1 - 4.1e-06 26.0 0.0 2.8e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 ATPase MipZ ArgK PF03308.11 AAS51915.1 - 0.00016 20.5 2.4 0.00021 20.2 0.4 1.8 1 1 1 2 2 2 1 ArgK protein ArsA_ATPase PF02374.10 AAS51915.1 - 0.00023 20.3 1.1 0.00071 18.7 0.7 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 AAS51915.1 - 0.0004 20.3 0.0 0.0017 18.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AAS51915.1 - 0.0051 16.2 0.0 0.0088 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.1 AAS51915.1 - 0.02 14.5 0.4 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain YhjQ PF06564.7 AAS51915.1 - 0.034 13.5 0.8 0.07 12.4 0.3 1.6 2 1 0 2 2 2 0 YhjQ protein APS_kinase PF01583.15 AAS51915.1 - 0.058 13.0 0.1 0.094 12.3 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF258 PF03193.11 AAS51915.1 - 0.063 12.4 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Fer4_NifH PF00142.13 AAS51915.1 - 0.085 12.0 0.1 0.18 10.9 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_10 PF12846.2 AAS51915.1 - 0.095 12.1 0.2 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain IstB_IS21 PF01695.12 AAS51915.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein ADIP PF11559.3 AAS51916.1 - 0.0048 16.8 2.5 0.0087 15.9 1.8 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding P4Ha_N PF08336.6 AAS51916.1 - 0.0077 16.0 0.4 0.016 15.0 0.3 1.5 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PMEI PF04043.10 AAS51916.1 - 0.013 15.3 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Laminin_II PF06009.7 AAS51916.1 - 0.015 15.0 2.3 0.025 14.3 0.2 2.0 1 1 1 2 2 2 0 Laminin Domain II SlyX PF04102.7 AAS51916.1 - 0.017 15.4 1.0 9.3 6.7 1.7 2.8 1 1 1 2 2 2 0 SlyX HR1 PF02185.11 AAS51916.1 - 0.04 13.6 2.2 0.088 12.5 1.5 1.7 1 0 0 1 1 1 0 Hr1 repeat AAA_13 PF13166.1 AAS51916.1 - 0.041 12.3 1.8 0.066 11.6 0.7 1.6 2 0 0 2 2 2 0 AAA domain TMPIT PF07851.8 AAS51916.1 - 0.045 12.8 1.9 0.064 12.3 1.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1640 PF07798.6 AAS51916.1 - 0.046 13.7 2.6 0.076 13.0 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) COG5 PF10392.4 AAS51916.1 - 0.066 13.1 3.1 0.13 12.1 2.2 1.5 1 1 0 1 1 1 0 Golgi transport complex subunit 5 DUF1664 PF07889.7 AAS51916.1 - 0.07 12.9 5.9 1.1 9.1 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tht1 PF04163.7 AAS51916.1 - 0.11 10.9 0.3 0.14 10.5 0.2 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Fib_alpha PF08702.5 AAS51916.1 - 0.13 12.3 2.9 0.22 11.6 2.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 AAS51916.1 - 0.59 10.4 5.0 4.6 7.5 3.4 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Fzo_mitofusin PF04799.8 AAS51916.1 - 1.2 8.4 5.4 3.3 7.0 3.8 1.6 1 1 0 1 1 1 0 fzo-like conserved region Prefoldin_2 PF01920.15 AAS51917.2 - 1.7e-23 82.3 7.4 1.9e-23 82.2 5.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 AAS51917.2 - 0.0012 18.5 4.0 0.014 15.0 2.8 2.0 1 1 0 1 1 1 1 Prefoldin subunit DUF342 PF03961.8 AAS51917.2 - 0.005 15.3 4.7 0.0071 14.8 3.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF342) Spc24 PF08286.6 AAS51917.2 - 0.029 14.0 7.3 0.31 10.7 1.3 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 RVT_3 PF13456.1 AAS51917.2 - 0.039 13.7 0.1 0.085 12.6 0.0 1.5 1 1 1 2 2 2 0 Reverse transcriptase-like DUF904 PF06005.7 AAS51917.2 - 0.057 13.7 8.1 0.78 10.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Rootletin PF15035.1 AAS51917.2 - 0.066 13.1 1.9 0.46 10.4 1.3 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Mnd1 PF03962.10 AAS51917.2 - 0.08 12.6 2.3 0.14 11.7 1.6 1.4 1 1 0 1 1 1 0 Mnd1 family IncA PF04156.9 AAS51917.2 - 0.12 11.9 3.9 0.64 9.5 2.7 1.8 1 1 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 AAS51917.2 - 0.13 12.1 6.5 1.1 9.1 0.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rep_3 PF01051.16 AAS51917.2 - 0.19 11.3 2.4 0.35 10.4 0.1 1.9 1 1 1 2 2 2 0 Initiator Replication protein Snapin_Pallidin PF14712.1 AAS51917.2 - 0.38 11.0 2.7 2.2 8.6 0.2 2.1 2 0 0 2 2 2 0 Snapin/Pallidin SAS4 PF15460.1 AAS51917.2 - 0.47 10.3 3.3 2.4 8.0 2.3 2.0 1 1 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 DUF2205 PF10224.4 AAS51917.2 - 0.86 9.2 4.7 1.2 8.7 0.3 2.2 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) BLOC1_2 PF10046.4 AAS51917.2 - 0.96 9.6 5.9 1.2 9.2 0.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.16 AAS51917.2 - 5 7.1 6.4 2.9 7.8 0.2 2.2 2 0 0 2 2 2 0 bZIP transcription factor DDOST_48kD PF03345.9 AAS51918.2 - 4.8e-133 443.7 0.9 5.5e-133 443.5 0.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta ABC_transp_aux PF09822.4 AAS51918.2 - 0.031 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Syja_N PF02383.13 AAS51919.1 - 2.1e-61 207.4 0.1 4.6e-61 206.3 0.1 1.5 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 AAS51919.1 - 1.2e-21 77.8 0.0 1.7e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NLE PF08154.7 AAS51919.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.9 1 0 0 1 1 1 0 NLE (NUC135) domain GPI-anchored PF10342.4 AAS51920.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RRM_1 PF00076.17 AAS51921.1 - 2.6e-18 65.4 0.0 4.3e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS51921.1 - 2.4e-14 53.0 0.0 4.1e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS51921.1 - 4.6e-09 35.9 0.0 9.6e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AAS51921.1 - 0.0017 18.1 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 AAS51921.1 - 0.0026 17.4 0.1 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nop16 PF09420.5 AAS51922.1 - 5.9e-60 202.0 8.2 6.9e-60 201.8 5.7 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 FYVE_2 PF02318.11 AAS51922.1 - 2.1 8.2 4.8 1.2 9.0 1.0 2.3 1 1 2 3 3 3 0 FYVE-type zinc finger PMI_typeI PF01238.16 AAS51923.1 - 5.9e-148 492.8 0.0 6.7e-148 492.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 AAS51923.1 - 0.00014 21.5 0.1 0.016 14.9 0.0 2.7 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.6 AAS51923.1 - 0.061 12.8 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Cupin domain Hexapep PF00132.19 AAS51924.2 - 3.1e-05 23.2 12.3 0.0013 18.1 1.0 4.9 4 1 2 6 6 6 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AAS51924.2 - 0.02 14.4 12.2 0.15 11.6 3.2 3.4 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase NAD_binding_10 PF13460.1 AAS51925.1 - 5.9e-11 42.6 0.2 1e-10 41.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 AAS51925.1 - 2.2e-06 26.3 0.0 0.00035 19.1 0.0 2.5 1 1 2 3 3 3 2 HIM1 NAD_binding_4 PF07993.7 AAS51925.1 - 0.0005 19.0 0.0 0.0088 14.9 0.0 2.6 1 1 1 2 2 2 1 Male sterility protein NmrA PF05368.8 AAS51925.1 - 0.0013 18.0 0.4 0.0027 17.0 0.1 1.7 2 1 0 2 2 2 1 NmrA-like family DUF296 PF03479.10 AAS51925.1 - 0.004 16.7 0.1 0.018 14.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF296) Semialdhyde_dh PF01118.19 AAS51925.1 - 0.017 15.3 0.1 0.047 13.9 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 AAS51925.1 - 0.039 13.3 0.1 0.11 11.9 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDA1_CD39 PF01150.12 AAS51926.2 - 2.5e-124 415.0 0.0 4.3e-124 414.3 0.0 1.3 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family TFIIB PF00382.14 AAS51927.2 - 2.2e-49 165.1 2.3 2.7e-26 91.1 0.5 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AAS51927.2 - 1.4e-13 49.9 0.8 2.4e-13 49.1 0.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Poxvirus PF06227.7 AAS51927.2 - 0.033 13.7 0.2 0.048 13.2 0.1 1.3 1 0 0 1 1 1 0 dsDNA Poxvirus Cyclin_C PF02984.14 AAS51927.2 - 0.042 13.7 0.1 0.15 11.9 0.0 2.0 3 0 0 3 3 3 0 Cyclin, C-terminal domain GN3L_Grn1 PF08701.6 AAS51928.2 - 5.3e-26 90.3 20.0 1.4e-25 88.9 13.9 1.8 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 AAS51928.2 - 2e-21 76.1 0.2 7.4e-16 58.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 AAS51928.2 - 2.4e-09 36.6 0.1 1.5e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 AAS51928.2 - 4.6e-05 22.9 0.0 0.018 14.4 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 AAS51928.2 - 0.00098 18.3 0.1 0.0018 17.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 AAS51928.2 - 0.0028 16.7 0.0 0.013 14.6 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 AAS51928.2 - 0.0034 17.2 5.8 0.67 9.7 0.0 3.7 3 1 1 4 4 4 2 Dynamin family Miro PF08477.8 AAS51928.2 - 0.012 16.1 0.1 0.5 10.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein cobW PF02492.14 AAS51928.2 - 0.035 13.5 0.2 0.5 9.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 AAS51928.2 - 0.093 11.4 0.0 0.093 11.4 0.0 2.2 2 0 0 2 2 2 0 ArgK protein CDC27 PF09507.5 AAS51928.2 - 0.16 11.1 18.5 0.34 10.0 12.8 1.6 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_18 PF13238.1 AAS51928.2 - 0.24 11.7 0.0 0.24 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 AAS51928.2 - 0.45 11.3 0.0 0.45 11.3 0.0 2.7 2 1 0 2 2 1 0 AAA domain LRR_4 PF12799.2 AAS51929.1 - 1.3e-16 59.7 20.0 1.9e-05 24.1 0.8 6.1 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) CAP_GLY PF01302.20 AAS51929.1 - 8.1e-16 57.4 0.0 1.3e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.1 AAS51929.1 - 2.1e-09 36.9 17.7 0.0095 15.6 2.0 5.9 2 2 5 7 7 7 5 Leucine rich repeat LRR_6 PF13516.1 AAS51929.1 - 2.5e-07 30.0 21.5 0.13 12.4 0.0 7.8 5 2 2 7 7 7 3 Leucine Rich repeat LRR_7 PF13504.1 AAS51929.1 - 0.00014 21.4 13.4 4.9 7.7 0.0 8.2 10 0 0 10 10 10 2 Leucine rich repeat LRR_9 PF14580.1 AAS51929.1 - 0.0058 16.1 9.8 0.044 13.3 0.4 4.2 2 1 3 5 5 5 1 Leucine-rich repeat LRR_1 PF00560.28 AAS51929.1 - 0.0092 15.8 20.6 4.2 7.7 0.0 8.4 7 3 1 8 8 8 2 Leucine Rich Repeat PUA PF01472.15 AAS51930.1 - 6.5e-20 70.6 0.0 1.4e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.5 AAS51930.1 - 0.04 13.6 0.8 0.059 13.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) DUF4443 PF14544.1 AAS51930.1 - 0.094 12.6 0.2 1.5 8.7 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4443) Helicase_C PF00271.26 AAS51931.2 - 9e-20 70.3 0.1 2.3e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AAS51931.2 - 6.1e-19 68.1 0.0 4.2e-18 65.3 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 AAS51931.2 - 9.1e-17 61.4 0.1 4.9e-16 59.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AAS51931.2 - 0.0084 16.2 0.0 0.034 14.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF1682 PF07946.9 AAS51931.2 - 9.4 4.9 11.0 45 2.7 7.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Sec3_C PF09763.4 AAS51932.2 - 1.4e-184 615.1 18.8 1.9e-184 614.6 13.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 AAS51932.2 - 1.1e-24 86.1 1.4 2.6e-24 84.8 0.1 2.3 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 AAS51932.2 - 1.7e-06 26.9 2.3 3.1e-06 26.0 1.6 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family F_actin_bind PF08919.5 AAS51932.2 - 0.00091 18.9 0.4 0.06 13.0 0.1 3.0 2 0 0 2 2 2 1 F-actin binding Sec3_C_2 PF15278.1 AAS51932.2 - 0.0016 18.4 1.4 0.012 15.7 0.1 2.8 2 0 0 2 2 2 1 Sec3 exocyst complex subunit NTF2 PF02136.15 AAS51933.1 - 5.5e-36 123.5 0.7 6.1e-36 123.3 0.5 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 AAS51933.1 - 0.0011 18.0 0.1 0.0016 17.5 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) DUF4440 PF14534.1 AAS51933.1 - 0.074 13.2 0.0 0.095 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF3210 PF11489.3 AAS51934.2 - 1.3e-09 37.3 35.3 2.5e-09 36.4 14.3 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3210) DnaJ-X PF14308.1 AAS51935.2 - 1.5e-62 210.5 6.8 2.4e-62 209.8 0.5 2.2 2 0 0 2 2 2 2 X-domain of DnaJ-containing DnaJ PF00226.26 AAS51935.2 - 1.4e-23 82.3 2.4 1.4e-23 82.3 1.6 2.2 2 0 0 2 2 2 1 DnaJ domain DUF4532 PF15046.1 AAS51935.2 - 0.039 12.9 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) Methyltransf_6 PF03737.10 AAS51936.1 - 1.3e-27 96.5 0.1 1.8e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase RRM_1 PF00076.17 AAS51937.1 - 1.1e-15 56.9 0.0 2e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS51937.1 - 7e-12 45.1 0.0 5.5e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS51937.1 - 9.7e-09 34.9 0.0 5.3e-08 32.6 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_4 PF12763.2 AAS51938.2 - 1.2e-25 89.2 0.0 6.7e-15 54.7 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 AAS51938.2 - 2.1e-09 36.0 0.0 0.00052 19.1 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 AAS51938.2 - 7e-08 32.4 0.0 7.6e-06 25.9 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 AAS51938.2 - 6e-06 25.7 0.1 0.14 12.0 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 AAS51938.2 - 0.0027 17.3 0.1 0.13 11.8 0.0 2.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 AAS51938.2 - 0.021 14.1 0.1 0.35 10.2 0.0 2.5 2 0 0 2 2 2 0 EF hand PA26 PF04636.8 AAS51938.2 - 0.058 12.0 15.3 0.16 10.6 3.6 2.5 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Dabb PF07876.7 AAS51938.2 - 0.08 13.3 1.6 4.3 7.8 0.0 3.4 3 0 0 3 3 3 0 Stress responsive A/B Barrel Domain SRP1_TIP1 PF00660.12 AAS51939.1 - 5.7e-10 38.9 0.0 1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Seripauperin and TIP1 family CDC27 PF09507.5 AAS51939.1 - 3.1 6.9 7.4 4 6.5 5.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2486 PF10667.4 AAS51939.1 - 4.3 7.8 16.0 6.3 7.2 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Mannosyl_trans3 PF11051.3 AAS51940.3 - 2.5e-41 141.8 0.0 3.2e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative ARD PF03079.9 AAS51941.1 - 3.4e-43 147.3 0.0 3.9e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 AAS51941.1 - 1.1e-09 37.5 0.1 2.2e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 AAS51941.1 - 1.4e-06 28.0 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.2 AAS51941.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Cupin DUF497 PF04365.8 AAS51941.1 - 0.037 13.9 0.1 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF497) Cupin_1 PF00190.17 AAS51941.1 - 0.08 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Cupin PQ-loop PF04193.9 AAS51942.2 - 1.5e-11 43.6 19.3 2e-09 36.8 1.8 4.1 3 1 0 3 3 3 3 PQ loop repeat Pet127 PF08634.5 AAS51943.1 - 3e-116 387.3 0.5 5.2e-116 386.6 0.2 1.5 2 0 0 2 2 2 1 Mitochondrial protein Pet127 TauD PF02668.11 AAS51944.1 - 2.2e-52 178.2 0.0 3e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 AAS51944.1 - 0.058 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 CsiD DUF971 PF06155.7 AAS51944.1 - 0.13 12.7 0.0 7.6 7.0 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF971) TP6A_N PF04406.9 AAS51945.1 - 2.3e-10 39.9 0.0 5.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 AAS51945.1 - 0.027 14.3 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) EMP24_GP25L PF01105.19 AAS51946.1 - 1.8e-34 119.0 0.0 2e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2569 PF10754.4 AAS51946.1 - 0.071 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) RPN7 PF10602.4 AAS51947.2 - 1.2e-52 177.8 3.9 1.2e-52 177.8 2.7 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 AAS51947.2 - 4.7e-16 58.9 0.1 1.8e-15 57.1 0.1 2.0 2 0 0 2 2 2 1 PCI domain Interferon PF00143.14 AAS51947.2 - 0.0017 18.2 0.1 0.0039 17.0 0.1 1.5 1 0 0 1 1 1 1 Interferon alpha/beta domain TPR_15 PF13429.1 AAS51947.2 - 0.0032 16.5 0.1 0.0063 15.6 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat PCI_Csn8 PF10075.4 AAS51947.2 - 0.0035 17.1 0.1 0.0077 16.0 0.0 1.7 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_11 PF13414.1 AAS51947.2 - 0.0087 15.6 0.2 0.032 13.8 0.1 2.0 1 0 0 1 1 1 1 TPR repeat DUF1955 PF09205.5 AAS51947.2 - 0.012 15.1 1.3 0.027 13.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) TPR_12 PF13424.1 AAS51947.2 - 0.026 14.4 2.2 0.05 13.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF357 PF04010.8 AAS51947.2 - 0.026 14.2 0.1 0.069 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF357) TPR_8 PF13181.1 AAS51947.2 - 0.028 14.2 0.3 0.1 12.4 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 AAS51947.2 - 0.032 14.0 0.6 0.5 10.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 AAS51947.2 - 0.042 13.7 1.0 0.24 11.4 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF948 PF06103.6 AAS51948.2 - 0.33 10.8 3.2 7 6.5 0.1 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cluap1 PF10234.4 AAS51948.2 - 0.51 9.5 19.1 0.35 10.0 3.4 2.7 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF2353 PF09789.4 AAS51948.2 - 0.51 9.5 30.2 0.031 13.5 7.5 2.2 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF1664 PF07889.7 AAS51948.2 - 1 9.1 9.4 17 5.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1515 PF07439.6 AAS51948.2 - 3.4 7.4 7.7 4.7 7.0 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) ATG16 PF08614.6 AAS51948.2 - 3.5 7.4 37.7 0.6 9.8 10.5 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) XhlA PF10779.4 AAS51948.2 - 9.1 6.2 18.1 6.2 6.8 3.0 3.8 2 1 2 4 4 4 0 Haemolysin XhlA Nrap PF03813.9 AAS51949.2 - 0 1246.9 0.1 0 1246.7 0.0 1.0 1 0 0 1 1 1 1 Nrap protein RNA_pol_A_bac PF01000.21 AAS51951.1 - 2e-29 101.9 0.0 5.2e-29 100.6 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AAS51951.1 - 8e-15 53.7 0.0 1.1e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Nop PF01798.13 AAS51952.3 - 1.7e-28 98.8 0.5 7.9e-28 96.6 0.3 1.9 2 0 0 2 2 2 1 Putative snoRNA binding domain Prp31_C PF09785.4 AAS51952.3 - 4.1e-15 56.3 0.1 6.5e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 AAS51952.3 - 5.7e-05 22.8 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain DUF3275 PF11679.3 AAS51952.3 - 4.1 6.9 4.8 4.6 6.8 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) Pkinase PF00069.20 AAS51953.1 - 3.5e-52 177.1 0.0 2.3e-51 174.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51953.1 - 1.7e-27 96.1 0.1 1.5e-18 66.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 AAS51953.1 - 1.4e-05 25.5 0.9 3.1e-05 24.4 0.6 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 AAS51953.1 - 0.00051 19.1 0.0 0.011 14.7 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 AAS51953.1 - 0.04 13.6 0.3 0.21 11.2 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family CwfJ_C_1 PF04677.10 AAS51954.2 - 2.2e-34 117.7 1.1 2.7e-34 117.4 0.1 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 AAS51954.2 - 7.8e-21 74.4 3.1 1.9e-20 73.1 2.2 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 HIT PF01230.18 AAS51954.2 - 0.013 16.0 0.1 0.028 14.9 0.1 1.5 1 0 0 1 1 1 0 HIT domain RRM_1 PF00076.17 AAS51955.2 - 1.3e-72 239.3 8.0 2.5e-18 65.4 0.0 6.1 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS51955.2 - 7.7e-65 214.8 0.9 2e-15 56.4 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS51955.2 - 1.2e-41 140.2 0.1 1.9e-09 37.2 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AAS51955.2 - 0.0014 18.3 0.0 5.9 6.7 0.0 4.4 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 AAS51955.2 - 0.17 11.6 3.0 5 6.9 0.0 3.6 3 1 1 4 4 4 0 Limkain b1 Mito_carr PF00153.22 AAS51956.1 - 1.7e-51 171.9 1.8 5.6e-18 64.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein LSM14 PF12701.2 AAS51957.2 - 3.3e-26 90.9 0.0 5.1e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 AAS51957.2 - 4e-11 43.3 6.2 7.5e-09 36.0 4.3 2.2 1 1 0 1 1 1 1 FDF domain SM-ATX PF14438.1 AAS51957.2 - 0.00012 21.8 0.1 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.6 AAS51957.2 - 1.4 9.4 11.6 0.24 11.8 5.0 1.8 2 0 0 2 2 2 0 Glycine rich protein family API5 PF05918.6 AAS51957.2 - 4.7 5.5 7.7 6.8 5.0 5.4 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Acetyltransf_1 PF00583.19 AAS51958.1 - 8.8e-10 38.4 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AAS51958.1 - 4.6e-05 23.0 0.0 8.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 AAS51958.1 - 0.007 16.4 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AAS51958.1 - 0.014 15.5 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_7 PF13176.1 AAS51958.1 - 0.18 11.6 0.4 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Leu_Phe_trans PF03588.9 AAS51959.1 - 0.015 14.4 1.8 1.6 7.8 0.3 2.3 2 0 0 2 2 2 0 Leucyl/phenylalanyl-tRNA protein transferase CNH PF00780.17 AAS51960.1 - 0.019 14.4 0.1 0.65 9.3 0.0 2.1 2 0 0 2 2 2 0 CNH domain MCM PF00493.18 AAS51961.1 - 2.5e-135 450.5 0.1 4.1e-135 449.8 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AAS51961.1 - 1.2e-27 96.7 0.2 6e-27 94.5 0.1 2.3 2 1 1 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 AAS51961.1 - 3.7e-08 32.7 0.1 8.5e-06 25.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AAS51961.1 - 3.3e-07 30.1 0.0 1.1e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 AAS51961.1 - 0.003 17.9 0.2 0.003 17.9 0.1 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AAS51961.1 - 0.015 14.8 0.0 0.058 13.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AAS51961.1 - 0.076 12.4 0.1 0.5 9.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Tricho_coat PF05892.6 AAS51962.1 - 0.022 13.9 0.1 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Trichovirus coat protein Arrestin_C PF02752.17 AAS51962.1 - 0.091 12.8 2.6 0.07 13.2 0.3 1.9 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain VPS28 PF03997.7 AAS51963.1 - 4.8e-66 221.9 0.1 5.6e-66 221.7 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein MSA-2c PF12238.3 AAS51963.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c GldM_N PF12081.3 AAS51963.1 - 0.062 12.8 0.0 3.6 7.0 0.0 2.5 2 0 0 2 2 2 0 GldM N-terminal domain Speriolin_C PF15059.1 AAS51963.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Speriolin C-terminus Pro_isomerase PF00160.16 AAS51964.1 - 1.4e-12 48.1 0.0 3.1e-12 46.9 0.0 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NIF PF03031.13 AAS51965.2 - 1.5e-37 128.7 0.1 2.2e-37 128.1 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Abhydrolase_6 PF12697.2 AAS51966.2 - 8.7e-17 61.7 0.0 2.2e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AAS51966.2 - 1.4e-08 34.5 0.0 6e-08 32.5 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AAS51966.2 - 2.8e-06 27.0 0.0 5.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 AAS51966.2 - 0.024 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 AAS51966.2 - 0.034 14.0 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF2424 PF10340.4 AAS51967.1 - 2.9e-27 95.2 0.0 3.9e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 AAS51967.1 - 6.5e-15 55.2 2.1 1.3e-14 54.2 1.2 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 AAS51967.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Glyco_transf_15 PF01793.11 AAS51968.1 - 4.4e-91 305.2 0.0 5.5e-91 304.9 0.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CorA PF01544.13 AAS51969.2 - 0.0094 15.0 5.8 0.02 13.9 4.0 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein GldH_lipo PF14109.1 AAS51969.2 - 0.032 14.4 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 GldH lipoprotein FTR1 PF03239.9 AAS51970.1 - 2.6e-93 312.3 9.2 3.1e-93 312.0 6.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Amidase PF01425.16 AAS51971.2 - 3.5e-88 296.3 2.6 5.7e-88 295.6 1.8 1.3 1 0 0 1 1 1 1 Amidase AHS2 PF02626.10 AAS51971.2 - 1.2e-87 293.6 0.0 1.9e-87 293.0 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 AAS51971.2 - 2.7e-62 209.8 0.0 5.1e-62 208.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 AAS51971.2 - 3.1e-44 150.8 0.0 6.2e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 AAS51971.2 - 6.3e-40 135.7 0.0 1.8e-39 134.2 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 AAS51971.2 - 1.1e-30 105.7 0.0 2.6e-30 104.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 AAS51971.2 - 1.1e-19 70.8 0.0 3.1e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 AAS51971.2 - 2.8e-16 58.8 2.3 9.4e-16 57.2 1.6 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 AAS51971.2 - 2.2e-13 50.0 0.0 4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 AAS51971.2 - 1.2e-12 47.1 0.0 1.4e-05 24.0 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AAS51971.2 - 8e-07 28.5 0.0 2e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 AAS51971.2 - 0.00016 21.5 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.1 AAS51971.2 - 0.0027 17.3 0.1 0.0061 16.2 0.1 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain NQRA PF05896.6 AAS51971.2 - 0.037 13.2 0.2 0.07 12.3 0.1 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.14 AAS51971.2 - 0.043 13.5 0.8 0.13 11.9 0.2 2.0 2 0 0 2 2 2 0 Glycine cleavage H-protein DUF4290 PF14123.1 AAS51971.2 - 0.13 11.4 0.3 1.6 7.8 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4290) HlyD_2 PF12700.2 AAS51971.2 - 0.28 10.2 3.2 2.5 7.1 0.1 2.7 2 1 1 3 3 3 0 HlyD family secretion protein AMP-binding PF00501.23 AAS51972.1 - 3.3e-73 246.4 0.0 3.8e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Glutaredoxin PF00462.19 AAS51973.1 - 1.4e-17 63.4 0.0 1.9e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Exo5 PF09810.4 AAS51974.1 - 1.2e-29 103.5 0.0 1.9e-28 99.6 0.0 2.6 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 AAS51974.1 - 5.7e-06 25.8 0.0 1.5e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 AAS51974.1 - 0.058 13.3 0.7 6.6 6.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF83 DUF2401 PF10287.4 AAS51976.1 - 6.3e-101 336.7 1.9 9.5e-101 336.1 1.3 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 AAS51976.1 - 2e-29 101.4 0.6 4.7e-29 100.3 0.0 2.0 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) Pkinase PF00069.20 AAS51978.1 - 2.8e-74 249.5 0.0 3.2e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS51978.1 - 1.3e-34 119.4 0.0 1.7e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS51978.1 - 5.5e-07 28.8 0.0 1.2e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AAS51978.1 - 0.0043 16.8 0.4 0.093 12.4 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AAS51978.1 - 0.025 13.6 0.3 0.096 11.7 0.1 2.0 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 AAS51978.1 - 0.13 11.0 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 adh_short PF00106.20 AAS51979.2 - 1.3e-22 80.5 0.6 2e-22 79.9 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AAS51979.2 - 1.6e-08 34.5 0.0 2.3e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AAS51979.2 - 3.1e-06 26.9 0.2 5.3e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AAS51979.2 - 0.0007 19.6 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 AAS51979.2 - 0.0042 16.0 0.0 0.0055 15.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 AAS51979.2 - 0.076 12.8 0.1 0.24 11.2 0.1 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Lge1 PF11488.3 AAS51980.1 - 5.1e-21 74.6 1.3 6.4e-21 74.3 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 Mito_fiss_reg PF05308.6 AAS51980.1 - 0.88 8.8 14.7 3.2 7.0 5.6 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator LRR_6 PF13516.1 AAS51981.1 - 4.2e-05 23.1 0.0 2.6 8.3 0.0 4.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 AAS51981.1 - 0.00034 20.1 0.0 1.7 8.3 0.3 3.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AAS51981.1 - 0.017 14.8 3.0 0.57 9.9 0.0 3.8 2 2 3 5 5 5 0 Leucine rich repeat LRR_7 PF13504.1 AAS51981.1 - 0.021 14.9 11.7 7.5 7.2 0.1 6.7 7 1 0 7 7 7 0 Leucine rich repeat LRR_1 PF00560.28 AAS51981.1 - 0.25 11.5 5.4 42 4.7 0.0 4.6 5 1 0 5 5 5 0 Leucine Rich Repeat zf-CCCH PF00642.19 AAS51982.1 - 3.4e-10 39.3 16.8 3.6e-06 26.5 2.0 2.8 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AAS51982.1 - 0.0012 18.7 15.9 0.052 13.5 3.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type TB2_DP1_HVA22 PF03134.14 AAS51983.2 - 6e-31 106.0 5.9 8.5e-31 105.5 4.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Adaptin_N PF01602.15 AAS51984.2 - 2e-101 339.9 13.4 2.4e-101 339.6 9.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 AAS51984.2 - 3.1e-07 30.7 0.1 6.1e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 AAS51984.2 - 0.00018 21.6 1.3 1.2 9.4 0.0 4.5 3 1 1 4 4 4 2 HEAT repeats Arrestin_C PF02752.17 AAS51985.2 - 5.1e-18 65.4 0.0 2.9e-17 63.0 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Got1 PF04178.7 AAS51986.2 - 1.6e-30 105.6 12.5 2.3e-30 105.1 8.7 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family EamA PF00892.15 AAS51986.2 - 2.6 8.0 15.2 1.1 9.2 1.9 2.2 1 1 1 2 2 2 0 EamA-like transporter family HLH PF00010.21 AAS51987.1 - 1.8e-12 46.7 0.8 1.8e-12 46.7 0.6 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Cyclin_N PF00134.18 AAS51988.1 - 6.6e-42 142.0 0.1 1.2e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AAS51988.1 - 6.7e-28 96.9 0.1 1.5e-27 95.8 0.0 1.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain Sas10 PF09368.5 AAS51989.1 - 5.5e-30 103.3 11.4 5.5e-30 103.3 7.9 2.3 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 AAS51989.1 - 5.2e-11 42.5 0.4 2.1e-10 40.6 0.0 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family RNA_pol_Rpc4 PF05132.9 AAS51990.2 - 1.6e-30 105.7 0.0 1.6e-30 105.7 0.0 2.4 3 0 0 3 3 3 1 RNA polymerase III RPC4 APG9 PF04109.11 AAS51991.1 - 3.1e-165 549.5 5.5 4.5e-165 549.0 3.8 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 Nop14 PF04147.7 AAS51992.1 - 9.4e-237 788.0 48.1 1.6e-235 783.9 33.3 2.0 1 1 0 1 1 1 1 Nop14-like family Peptidase_M16 PF00675.15 AAS51992.1 - 0.12 12.0 5.3 0.088 12.5 0.6 2.9 3 0 0 3 3 3 0 Insulinase (Peptidase family M16) PCI PF01399.22 AAS51993.2 - 1.1e-21 77.1 0.4 4e-21 75.2 0.0 2.2 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 AAS51993.2 - 0.011 15.5 0.3 0.25 11.1 0.0 2.5 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 DUF2216 PF10226.4 AAS51994.2 - 0.012 15.1 1.0 0.012 15.1 0.7 1.7 2 0 0 2 2 2 0 Uncharacterized conserved proteins (DUF2216) DUF1465 PF07323.7 AAS51994.2 - 0.03 13.8 0.6 0.035 13.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) EF_TS PF00889.14 AAS51994.2 - 0.062 12.6 0.1 0.079 12.2 0.1 1.1 1 0 0 1 1 1 0 Elongation factor TS FAD_binding_1 PF00667.15 AAS51994.2 - 0.07 12.5 0.7 0.092 12.1 0.5 1.1 1 0 0 1 1 1 0 FAD binding domain DUF972 PF06156.8 AAS51994.2 - 1.4 9.3 6.2 0.7 10.2 2.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Spectrin PF00435.16 AAS51994.2 - 2.4 8.4 8.5 0.24 11.6 2.8 1.7 2 0 0 2 2 2 0 Spectrin repeat DUF2013 PF09431.5 AAS51995.2 - 4.1e-43 146.4 13.5 4.1e-43 146.4 9.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Tubulin PF00091.20 AAS51996.1 - 4e-68 229.4 0.1 6e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AAS51996.1 - 7.4e-30 103.5 0.1 1.5e-29 102.5 0.0 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 AAS51996.1 - 2.7e-06 27.3 0.0 6.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF3658 PF12395.3 AAS51996.1 - 0.049 13.1 0.0 8.4 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function Coatomer_WDAD PF04053.9 AAS51997.1 - 5.2e-134 447.3 2.4 7.4e-134 446.8 1.7 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 AAS51997.1 - 1.2e-70 238.1 0.1 1.7e-70 237.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 AAS51997.1 - 1.2e-55 183.4 15.9 7.9e-10 38.2 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat eIF2A PF08662.6 AAS51997.1 - 3.2e-05 23.7 0.3 1.7 8.2 0.0 4.3 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 AAS51997.1 - 0.00034 18.9 4.9 1.2 7.1 0.0 3.5 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Glyco_hydro_16 PF00722.16 AAS51998.1 - 8.6e-46 155.5 0.8 1.5e-45 154.7 0.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Nodulin_late PF07127.6 AAS51998.1 - 0.075 13.1 0.2 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Late nodulin protein Chitin_bind_1 PF00187.14 AAS51998.1 - 0.14 12.1 13.0 0.28 11.2 9.0 1.4 1 0 0 1 1 1 0 Chitin recognition protein ApbA_C PF08546.6 AAS51999.1 - 2.1e-28 98.8 0.0 3.2e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 AAS51999.1 - 2.9e-18 65.7 0.0 4.3e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 AAS51999.1 - 0.00026 21.3 0.5 0.0023 18.2 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AAS51999.1 - 0.00073 18.5 0.1 0.001 18.0 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.16 AAS51999.1 - 0.0012 18.6 0.3 0.0045 16.8 0.1 2.0 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 AAS51999.1 - 0.0031 17.6 0.0 0.0063 16.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 AAS51999.1 - 0.011 15.7 0.2 0.021 14.8 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 AAS51999.1 - 0.019 13.8 0.5 0.029 13.2 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 AAS51999.1 - 0.039 14.2 0.0 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 AAS51999.1 - 0.1 12.6 1.2 0.2 11.6 0.8 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AAS51999.1 - 0.11 11.3 0.3 0.2 10.4 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 AAS51999.1 - 0.11 11.4 0.2 0.19 10.7 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_8 PF08022.7 AAS52000.1 - 4.4e-21 74.7 0.0 1.3e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 AAS52000.1 - 1.6e-20 73.4 8.1 1.6e-20 73.4 5.6 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 AAS52000.1 - 4.1e-10 39.7 0.0 1.2e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 AAS52000.1 - 0.027 14.6 9.5 0.036 14.1 0.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) CFEM PF05730.6 AAS52000.1 - 0.12 12.2 2.0 0.21 11.4 1.4 1.3 1 0 0 1 1 1 0 CFEM domain D123 PF07065.9 AAS52001.1 - 5.7e-114 380.2 0.0 6.6e-114 379.9 0.0 1.0 1 0 0 1 1 1 1 D123 D123 PF07065.9 AAS52002.1 - 2.8e-101 338.5 0.0 3.2e-101 338.3 0.0 1.0 1 0 0 1 1 1 1 D123 Cpn60_TCP1 PF00118.19 AAS52003.1 - 4.2e-134 447.8 12.4 4.8e-134 447.6 8.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CDP-OH_P_transf PF01066.16 AAS52004.2 - 1.2e-17 64.0 3.6 1.8e-17 63.4 2.5 1.4 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase BPL_N PF09825.4 AAS52005.1 - 2.8e-135 450.8 0.0 3.5e-135 450.5 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 AAS52005.1 - 9.1e-12 45.0 0.0 2.2e-11 43.8 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 AAS52005.1 - 0.0002 20.9 0.0 0.00038 20.0 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain RNA_pol_Rpb1_1 PF04997.7 AAS52006.2 - 6.6e-120 400.3 0.0 1.4e-119 399.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 AAS52006.2 - 1.7e-108 362.0 0.3 2.9e-108 361.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 AAS52006.2 - 1e-72 243.4 0.0 2.5e-72 242.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 AAS52006.2 - 8.8e-65 217.9 0.5 8.8e-65 217.9 0.3 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 AAS52006.2 - 8.3e-49 165.3 0.0 4.8e-48 162.8 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 AAS52006.2 - 1.1e-46 157.9 3.5 2.3e-46 156.8 2.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 AAS52006.2 - 8.7e-36 121.9 0.1 2.2e-35 120.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 AAS52006.2 - 1.7e-18 65.0 308.1 0.044 13.8 9.2 15.6 7 1 0 15 15 15 14 RNA polymerase Rpb1 C-terminal repeat DUF4123 PF13503.1 AAS52006.2 - 0.2 11.6 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) Pro_isomerase PF00160.16 AAS52007.1 - 1.2e-43 149.0 0.0 1.6e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.23 AAS52007.1 - 3.8e-08 32.6 0.4 1.4e-05 24.4 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 AAS52007.1 - 3.2e-06 26.6 9.7 0.0075 15.8 0.9 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 AAS52007.1 - 3.4e-06 26.5 6.3 0.00024 20.7 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 AAS52007.1 - 0.0023 17.5 0.1 0.0091 15.7 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.12 AAS52007.1 - 0.063 13.5 4.7 0.065 13.5 2.1 1.8 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 AAS52007.1 - 0.068 13.6 3.5 1.3 9.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 AAS52007.1 - 0.084 13.1 0.9 4.3 7.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 AAS52007.1 - 0.12 12.2 9.8 0.32 10.9 3.3 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 AAS52007.1 - 0.52 10.1 6.9 0.071 12.9 1.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 AAS52007.1 - 2.4 9.0 12.6 7.7 7.4 0.3 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Scm3 PF10384.4 AAS52008.1 - 1.3e-23 82.2 1.8 1.4e-23 82.1 0.3 1.7 2 0 0 2 2 2 1 Centromere protein Scm3 PEP-utilisers_N PF05524.8 AAS52008.1 - 0.058 13.1 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal CHCH PF06747.8 AAS52009.1 - 0.00026 20.7 1.9 0.00039 20.2 1.3 1.3 1 0 0 1 1 1 1 CHCH domain Sec31 PF11549.3 AAS52010.2 - 6e-28 96.2 7.8 1.7e-27 94.7 3.5 3.0 3 0 0 3 3 3 1 Protein transport protein SEC31 WD40 PF00400.27 AAS52010.2 - 7.6e-16 57.3 7.6 7.2e-05 22.5 0.1 7.0 8 0 0 8 8 8 4 WD domain, G-beta repeat SRA1 PF07304.6 AAS52010.2 - 1.6e-10 40.9 0.0 6.4e-10 38.9 0.0 2.1 1 1 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 AAS52010.2 - 1.2e-05 25.2 1.4 1.8e-05 24.6 1.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.10 AAS52010.2 - 0.13 12.1 2.4 0.27 11.0 0.1 2.4 2 1 1 3 3 3 0 Prp18 domain Sugar_tr PF00083.19 AAS52011.2 - 1.6e-116 389.5 31.7 1.8e-116 389.3 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AAS52011.2 - 3.4e-12 45.7 46.8 3.1e-10 39.3 9.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 AAS52011.2 - 0.87 9.6 5.4 1.7 8.7 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Prenyltransf PF01255.14 AAS52012.1 - 0.0012 18.0 0.0 0.0033 16.5 0.0 1.8 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase PTCRA PF15028.1 AAS52012.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Pre-T-cell antigen receptor DUF1003 PF06210.6 AAS52012.1 - 0.088 12.7 0.7 0.16 11.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Arf PF00025.16 AAS52013.1 - 4.6e-29 100.8 0.0 5.8e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AAS52013.1 - 2e-05 23.9 0.1 0.00011 21.4 0.1 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 AAS52013.1 - 0.00031 19.5 0.1 0.00057 18.6 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Miro PF08477.8 AAS52013.1 - 0.00036 21.0 0.0 0.00052 20.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AAS52013.1 - 0.0015 18.4 0.1 0.011 15.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 AAS52013.1 - 0.002 18.1 5.7 0.058 13.3 0.1 2.4 1 1 1 2 2 2 2 AAA ATPase domain Ras PF00071.17 AAS52013.1 - 0.0026 17.1 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Ras family AAA_33 PF13671.1 AAS52013.1 - 0.018 14.8 0.2 0.031 14.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 AAS52013.1 - 0.019 14.6 1.0 1.8 8.1 0.7 2.1 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 AAS52013.1 - 0.032 14.5 0.0 0.038 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 AAS52013.1 - 0.039 13.4 0.0 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 AAS52013.1 - 0.039 13.0 0.0 0.082 12.0 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 AAS52013.1 - 0.061 13.4 0.1 0.21 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 AAS52013.1 - 0.088 12.2 0.8 6.5 6.1 0.2 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 AAS52014.1 - 1.9e-79 264.9 0.0 2.1e-79 264.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AAS52014.1 - 4.9e-15 55.2 0.0 6.1e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AAS52014.1 - 6.8e-14 51.5 0.0 7.3e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 AAS52014.1 - 1.1e-12 47.3 0.8 8.4e-10 37.8 0.1 2.2 1 1 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 AAS52014.1 - 7e-12 44.9 0.0 8.4e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AAS52014.1 - 3.7e-11 43.5 0.0 4.8e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AAS52014.1 - 6.9e-06 26.0 0.0 9.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AAS52014.1 - 0.0045 16.4 0.1 0.021 14.2 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRP54 PF00448.17 AAS52014.1 - 0.0058 16.0 0.5 0.011 15.1 0.1 1.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 AAS52014.1 - 0.0078 16.1 0.1 0.013 15.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 AAS52014.1 - 0.029 14.0 0.6 3.3 7.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 AAS52014.1 - 0.029 13.8 0.3 6.3 6.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain 6PF2K PF01591.13 AAS52014.1 - 0.057 12.4 1.1 0.28 10.1 0.8 1.9 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DBD_Tnp_Mut PF03108.10 AAS52014.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 MuDR family transposase PduV-EutP PF10662.4 AAS52014.1 - 0.11 11.9 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 AAS52014.1 - 0.12 12.7 0.1 0.25 11.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.12 AAS52014.1 - 0.15 11.4 1.1 0.91 8.8 0.2 2.0 2 0 0 2 2 2 0 Thymidylate kinase AAA_17 PF13207.1 AAS52014.1 - 0.19 12.5 0.8 0.54 11.0 0.5 1.8 1 1 0 1 1 1 0 AAA domain Ribosomal_L29 PF00831.18 AAS52015.1 - 1.1e-15 57.0 3.5 1.1e-15 57.0 2.5 2.3 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.8 AAS52015.1 - 0.039 13.8 2.5 0.072 13.0 0.6 2.2 1 1 1 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Annexin PF00191.15 AAS52015.1 - 0.092 12.6 0.7 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 Annexin DUF4600 PF15372.1 AAS52015.1 - 1.5 9.0 8.8 5.4 7.2 6.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Ufd2P_core PF10408.4 AAS52016.1 - 2.1e-192 640.7 14.1 2.5e-192 640.4 9.8 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 AAS52016.1 - 2.6e-28 97.7 2.6 4.3e-28 97.0 0.8 2.1 2 0 0 2 2 2 1 U-box domain R3H PF01424.17 AAS52017.1 - 9.6e-12 44.4 0.4 2.1e-11 43.3 0.3 1.6 1 0 0 1 1 1 1 R3H domain Rho_GDI PF02115.12 AAS52018.1 - 9.9e-66 220.9 2.3 1.1e-65 220.8 1.6 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.23 AAS52019.1 - 2e-39 135.0 0.4 2.5e-39 134.7 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ATP-synt_ab PF00006.20 AAS52022.2 - 5.2e-123 408.5 0.0 8e-123 407.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AAS52022.2 - 1.4e-19 70.6 0.1 2.7e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AAS52022.2 - 1.1e-15 57.5 2.3 2.9e-15 56.2 1.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 AAS52022.2 - 0.0056 16.5 0.0 0.024 14.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain Ribosomal_L41 PF05162.8 AAS52023.1 - 9.5e-09 34.7 25.2 1e-08 34.7 17.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 DUF1601 PF07671.6 AAS52023.1 - 0.18 11.4 1.3 0.2 11.3 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1601) Mit_KHE1 PF10173.4 AAS52024.1 - 5.1e-57 192.7 0.1 7e-57 192.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related DUF1796 PF08795.5 AAS52024.1 - 0.015 14.9 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) MARVEL PF01284.18 AAS52025.1 - 0.0035 17.1 1.7 0.0056 16.5 1.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF3671 PF12420.3 AAS52025.1 - 0.29 11.1 2.8 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function Cullin PF00888.17 AAS52026.2 - 2.8e-152 508.2 10.9 3.9e-152 507.8 7.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 AAS52026.2 - 3.3e-24 84.4 3.1 4.2e-24 84.1 0.7 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain Apc4 PF12896.2 AAS52026.2 - 0.017 14.4 2.3 0.032 13.5 0.5 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 Penicillinase_R PF03965.11 AAS52026.2 - 0.046 13.8 2.2 0.16 12.1 0.0 2.9 3 0 0 3 3 3 0 Penicillinase repressor HMGL-like PF00682.14 AAS52027.2 - 5.3e-74 248.8 0.2 9.4e-74 248.0 0.1 1.4 1 0 0 1 1 1 1 HMGL-like ADP_PFK_GK PF04587.10 AAS52027.2 - 0.021 13.0 0.0 0.033 12.3 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region FliG_N PF14842.1 AAS52027.2 - 0.094 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 FliG N-terminal domain WD40 PF00400.27 AAS52028.1 - 1.1e-17 63.1 7.6 7.5e-06 25.6 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ PF01011.16 AAS52028.1 - 0.0067 15.9 0.1 0.14 11.7 0.0 2.8 2 0 0 2 2 2 1 PQQ enzyme repeat Chorion_1 PF01723.11 AAS52028.1 - 0.044 13.6 0.5 0.11 12.3 0.4 1.7 1 0 0 1 1 1 0 Chorion protein IATP PF04568.7 AAS52029.1 - 2.5e-23 81.9 3.0 2.7e-23 81.8 2.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP FbpA PF05833.6 AAS52029.1 - 0.0033 16.0 2.1 0.0033 16.0 1.5 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Fib_alpha PF08702.5 AAS52029.1 - 0.0036 17.4 0.2 0.0036 17.4 0.1 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family LRS4 PF10422.4 AAS52029.1 - 0.031 13.6 1.1 0.029 13.7 0.8 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 IncA PF04156.9 AAS52029.1 - 0.043 13.4 1.1 0.037 13.6 0.8 1.1 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 AAS52029.1 - 0.046 12.6 1.6 0.039 12.8 1.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_23 PF13476.1 AAS52029.1 - 0.067 13.5 2.9 0.062 13.6 2.0 1.1 1 0 0 1 1 1 0 AAA domain PspB PF06667.7 AAS52029.1 - 0.074 12.9 3.1 0.1 12.5 2.2 1.2 1 0 0 1 1 1 0 Phage shock protein B DUF500 PF04366.7 AAS52029.1 - 0.11 11.9 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF500) DUF2986 PF11661.3 AAS52029.1 - 0.16 12.3 1.6 0.19 12.0 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2986) HR1 PF02185.11 AAS52029.1 - 0.18 11.5 7.1 0.064 13.0 3.3 1.5 2 0 0 2 2 2 0 Hr1 repeat PilO PF04350.8 AAS52029.1 - 0.63 9.9 5.6 0.97 9.3 3.9 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilO DASH_Dad2 PF08654.5 AAS52029.1 - 0.92 9.5 4.7 1.4 8.9 3.3 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad2 DivIC PF04977.10 AAS52029.1 - 2.2 7.8 9.7 3.7 7.1 6.6 1.6 1 1 0 1 1 1 0 Septum formation initiator Pox_A_type_inc PF04508.7 AAS52029.1 - 4.9 7.1 6.5 0.95 9.4 1.1 2.3 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat tRNA_m1G_MT PF01746.16 AAS52030.1 - 3.5e-38 131.0 0.1 9.9e-38 129.5 0.0 1.7 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase BRCT PF00533.21 AAS52030.1 - 0.034 14.2 0.1 8.4 6.6 0.0 3.0 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AAS52030.1 - 0.09 12.6 0.3 0.78 9.6 0.0 2.5 3 0 0 3 3 3 0 twin BRCT domain Rep_fac_C PF08542.6 AAS52031.1 - 1.7e-21 75.9 0.1 1.9e-20 72.6 0.0 2.5 3 0 0 3 3 2 1 Replication factor C C-terminal domain AAA PF00004.24 AAS52031.1 - 9.1e-14 51.7 0.0 2.6e-13 50.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 AAS52031.1 - 2e-13 50.3 0.0 3e-11 43.2 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 AAS52031.1 - 1.3e-07 31.8 0.0 6.6e-06 26.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 AAS52031.1 - 1.8e-07 31.1 0.0 3.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 AAS52031.1 - 4.6e-07 28.9 0.1 0.00057 18.6 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AAS52031.1 - 2.5e-06 27.6 0.1 0.042 13.9 0.0 2.6 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 AAS52031.1 - 3.2e-06 26.3 0.1 1.2e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 AAS52031.1 - 7.7e-06 25.5 0.0 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 AAS52031.1 - 2.7e-05 23.8 0.0 7e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.8 AAS52031.1 - 3.9e-05 23.2 0.2 6e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 AAS52031.1 - 0.00031 19.9 0.0 0.0043 16.2 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 AAS52031.1 - 0.00087 18.8 0.0 0.14 11.5 0.0 2.4 1 1 0 2 2 2 1 AAA-like domain FtsK_SpoIIIE PF01580.13 AAS52031.1 - 0.0064 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_19 PF13245.1 AAS52031.1 - 0.007 16.0 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain ArgK PF03308.11 AAS52031.1 - 0.0079 14.9 0.0 0.071 11.8 0.0 2.3 1 1 1 2 2 2 1 ArgK protein DEAD PF00270.24 AAS52031.1 - 0.012 15.1 0.1 0.67 9.4 0.0 3.0 1 1 1 3 3 3 0 DEAD/DEAH box helicase NTPase_1 PF03266.10 AAS52031.1 - 0.013 15.2 0.1 0.12 12.0 0.0 2.3 1 1 1 2 2 2 0 NTPase AAA_11 PF13086.1 AAS52031.1 - 0.02 14.4 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 AAS52031.1 - 0.057 12.6 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 AAS52031.1 - 0.081 13.2 0.0 0.2 11.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain SRP54 PF00448.17 AAS52031.1 - 0.082 12.3 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_31 PF13614.1 AAS52031.1 - 0.09 12.7 0.0 0.56 10.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain ATP_bind_2 PF03668.10 AAS52031.1 - 0.17 10.9 0.8 17 4.3 0.1 2.9 2 1 1 3 3 3 0 P-loop ATPase protein family Vps52 PF04129.7 AAS52032.2 - 8e-133 443.6 11.1 1.1e-132 443.2 7.7 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family UvrD_C PF13361.1 AAS52033.1 - 1.6e-42 146.2 0.0 1.7e-41 142.8 0.0 2.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 AAS52033.1 - 1e-34 120.2 2.7 5.7e-17 61.9 0.0 3.5 3 2 0 4 4 4 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 AAS52033.1 - 8.2e-11 41.5 0.0 5.9e-10 38.7 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 AAS52033.1 - 6.7e-10 38.8 0.0 0.0062 16.0 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 AAS52033.1 - 1.2e-09 38.2 0.0 4.1e-09 36.5 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.1 AAS52033.1 - 6.8e-08 32.3 0.4 1.2e-06 28.3 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 AAS52033.1 - 0.00014 21.5 0.0 0.03 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AAS52033.1 - 0.0022 18.1 0.1 1.7 8.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain DEAD PF00270.24 AAS52033.1 - 0.11 11.9 0.0 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF2075 PF09848.4 AAS52033.1 - 0.12 11.3 4.4 0.47 9.3 0.1 3.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) YL1 PF05764.8 AAS52034.1 - 3.1e-55 187.4 29.3 3.1e-55 187.4 20.3 2.6 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 AAS52034.1 - 9.5e-12 44.2 0.1 1.7e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Methyltransf_23 PF13489.1 AAS52035.1 - 1.1e-24 86.9 0.0 1.8e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AAS52035.1 - 1e-18 67.5 0.0 2e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS52035.1 - 1.7e-17 63.4 0.0 2.7e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AAS52035.1 - 2.9e-15 56.5 0.0 5.3e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS52035.1 - 1e-13 51.8 0.0 1.8e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AAS52035.1 - 3.9e-10 39.9 0.0 6.8e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AAS52035.1 - 4.2e-08 32.6 0.0 5.5e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 AAS52035.1 - 6.9e-07 28.6 0.0 1.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 AAS52035.1 - 1.2e-06 27.9 0.0 3.2e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW NodS PF05401.6 AAS52035.1 - 1.4e-06 27.8 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 AAS52035.1 - 1.5e-06 28.2 0.0 6.2e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 AAS52035.1 - 2.3e-05 23.4 0.0 3.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 AAS52035.1 - 2.5e-05 23.6 0.0 5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 AAS52035.1 - 7.2e-05 22.0 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 AAS52035.1 - 0.00084 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 AAS52035.1 - 0.026 14.1 0.0 0.17 11.5 0.0 2.2 2 1 0 2 2 2 0 Hypothetical methyltransferase CheR PF01739.13 AAS52035.1 - 0.039 13.2 0.0 5.1 6.3 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Snf7 PF03357.16 AAS52036.1 - 2.5e-36 124.6 12.3 3.2e-36 124.2 8.6 1.2 1 0 0 1 1 1 1 Snf7 YlqD PF11068.3 AAS52036.1 - 0.00026 21.0 7.3 0.00026 21.0 5.1 2.2 1 1 1 2 2 2 1 YlqD protein Cep57_MT_bd PF06657.8 AAS52036.1 - 0.023 14.6 3.8 0.023 14.6 2.6 2.6 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF3829 PF12889.2 AAS52036.1 - 0.047 12.8 6.8 0.033 13.3 3.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) Atg14 PF10186.4 AAS52036.1 - 0.05 12.5 12.4 0.074 11.9 8.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 AAS52036.1 - 0.15 11.6 11.9 0.054 13.1 2.6 2.2 1 1 1 2 2 2 0 Mnd1 family DUF948 PF06103.6 AAS52036.1 - 0.29 11.0 6.3 9.7 6.1 2.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) YkyA PF10368.4 AAS52036.1 - 0.29 10.4 6.8 0.45 9.8 4.7 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein BLOC1_2 PF10046.4 AAS52036.1 - 0.32 11.1 16.3 0.68 10.1 4.5 3.0 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Peptidase_S46 PF10459.4 AAS52036.1 - 0.54 8.6 9.8 0.65 8.3 6.8 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF3584 PF12128.3 AAS52036.1 - 0.6 7.3 17.1 0.9 6.7 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4140 PF13600.1 AAS52036.1 - 0.63 10.5 0.1 0.63 10.5 0.1 3.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) COG2 PF06148.6 AAS52036.1 - 0.63 9.9 7.9 0.74 9.6 1.9 2.6 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Seryl_tRNA_N PF02403.17 AAS52036.1 - 0.73 9.8 13.1 1.1 9.3 2.7 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.3 AAS52036.1 - 0.86 9.4 21.8 0.34 10.7 0.7 3.3 2 1 2 4 4 3 0 TATA element modulatory factor 1 DNA binding DUF2203 PF09969.4 AAS52036.1 - 0.9 9.7 5.8 2.5 8.3 1.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Prefoldin PF02996.12 AAS52036.1 - 1.4 8.5 12.9 0.53 9.9 0.1 3.6 1 1 4 5 5 5 0 Prefoldin subunit CCDC-167 PF15188.1 AAS52036.1 - 2.2 8.2 7.5 20 5.2 0.0 3.3 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 AAA_13 PF13166.1 AAS52036.1 - 2.2 6.6 10.2 9.4 4.5 7.1 1.7 1 1 0 1 1 1 0 AAA domain DUF4407 PF14362.1 AAS52036.1 - 2.6 6.8 15.1 3.9 6.3 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.8 AAS52036.1 - 2.8 7.3 12.9 4.2 6.7 0.4 3.0 1 1 2 3 3 3 0 fzo-like conserved region Exonuc_VII_L PF02601.10 AAS52036.1 - 3 6.9 12.3 3.9 6.5 8.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.7 AAS52036.1 - 3.5 7.4 8.8 1.6 8.5 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HlyD PF00529.15 AAS52036.1 - 3.7 6.7 24.9 18 4.5 17.0 1.9 1 1 1 2 2 2 0 HlyD family secretion protein Uso1_p115_C PF04871.8 AAS52036.1 - 3.8 7.4 16.3 1.5 8.7 5.8 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF972 PF06156.8 AAS52036.1 - 4.5 7.6 13.6 48 4.3 4.9 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fmp27_WPPW PF10359.4 AAS52036.1 - 8 4.7 11.5 3.9 5.7 3.8 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain APG6 PF04111.7 AAS52036.1 - 9.1 5.2 16.7 1.7 7.6 4.0 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 tRNA-synt_1b PF00579.20 AAS52037.1 - 3e-18 65.9 0.0 4.3e-12 45.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) DHBP_synthase PF00926.14 AAS52038.1 - 5e-76 254.2 0.9 5.6e-76 254.0 0.7 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase RRM_5 PF13893.1 AAS52038.1 - 0.09 12.6 0.1 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) A_deaminase PF00962.17 AAS52039.1 - 2.7e-14 52.8 0.0 7.7e-08 31.6 0.0 3.4 3 1 0 3 3 3 2 Adenosine/AMP deaminase DUF619 PF04768.8 AAS52040.1 - 2.1e-51 173.7 0.0 3.5e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Sld5 PF05916.6 AAS52041.1 - 1.6e-18 66.9 0.3 2.2e-18 66.5 0.2 1.2 1 0 0 1 1 1 1 GINS complex protein DUF1426 PF07234.6 AAS52042.1 - 0.15 11.8 2.8 0.36 10.5 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) CDC45 PF02724.9 AAS52042.1 - 2.4 6.1 31.9 3.2 5.6 22.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 AAS52042.1 - 6.8 5.9 24.9 11 5.2 17.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Peptidase_M28 PF04389.12 AAS52043.1 - 7.5e-36 123.5 0.0 1.1e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 AAS52043.1 - 6.6e-13 48.2 0.0 2e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 AAS52043.1 - 0.0023 17.4 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 AAS52043.1 - 0.029 13.1 0.0 0.066 11.9 0.0 1.5 1 1 0 1 1 1 0 M42 glutamyl aminopeptidase DnaJ PF00226.26 AAS52044.2 - 2.2e-21 75.3 2.4 2.2e-21 75.3 1.6 2.3 2 0 0 2 2 2 1 DnaJ domain tRNA-synt_1g PF09334.6 AAS52045.2 - 0.0052 15.4 0.3 0.0059 15.3 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) PG_binding_1 PF01471.13 AAS52046.2 - 0.0013 18.6 0.1 0.031 14.2 0.0 2.9 3 0 0 3 3 3 1 Putative peptidoglycan binding domain CENP-F_N PF10481.4 AAS52046.2 - 0.12 11.7 0.8 0.23 10.7 0.6 1.4 1 0 0 1 1 1 0 Cenp-F N-terminal domain V_ATPase_I PF01496.14 AAS52047.2 - 2.1e-278 925.3 4.1 2.3e-278 925.1 2.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family PI3K_p85B PF02192.11 AAS52047.2 - 0.028 13.8 0.1 0.073 12.4 0.1 1.7 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain TMF_TATA_bd PF12325.3 AAS52047.2 - 0.033 13.9 0.7 4 7.1 0.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Transposase_24 PF03004.9 AAS52047.2 - 0.055 13.3 0.3 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) HSP70 PF00012.15 AAS52048.1 - 5.5e-46 156.6 0.1 5.5e-46 156.6 0.1 2.0 2 1 0 2 2 2 1 Hsp70 protein MoCF_biosynth PF00994.19 AAS52048.1 - 0.057 12.8 0.0 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 Probable molybdopterin binding domain RabGAP-TBC PF00566.13 AAS52051.1 - 1e-38 132.9 0.0 1.5e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cu-oxidase_2 PF07731.9 AAS52052.1 - 5.9e-47 158.6 5.7 9e-40 135.3 0.3 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 AAS52052.1 - 4.2e-38 129.7 9.7 2.8e-37 127.0 0.5 4.2 4 1 1 5 5 5 2 Multicopper oxidase Cu-oxidase PF00394.17 AAS52052.1 - 1.2e-32 112.9 10.2 6.3e-32 110.6 0.9 4.5 4 1 1 5 5 5 1 Multicopper oxidase Gifsy-2 PF13856.1 AAS52052.1 - 0.0098 16.0 0.2 1.9 8.6 0.0 2.6 2 0 0 2 2 2 1 ATP-binding sugar transporter from pro-phage Pox_A22 PF04848.8 AAS52053.1 - 0.096 12.5 0.4 0.25 11.2 0.2 1.6 1 0 0 1 1 1 0 Poxvirus A22 protein DUF4448 PF14610.1 AAS52054.1 - 9.2e-51 172.0 0.1 1.5e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Sen15 PF09631.5 AAS52055.1 - 3e-27 94.8 0.0 3.4e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Sen15 protein Tom37_C PF11801.3 AAS52056.1 - 4.9e-38 130.6 0.0 7e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 AAS52056.1 - 7.7e-22 77.3 0.0 1.3e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Suf PF05843.9 AAS52057.1 - 9.1e-70 235.5 24.9 3.2e-62 210.8 5.8 4.4 3 2 0 4 4 4 2 Suppressor of forked protein (Suf) ArgJ PF01960.13 AAS52058.2 - 4.3e-139 463.2 4.1 4.8e-139 463.0 2.8 1.0 1 0 0 1 1 1 1 ArgJ family Sugar_tr PF00083.19 AAS52059.1 - 2.1e-111 372.6 16.6 2.4e-111 372.4 11.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AAS52059.1 - 1.8e-20 72.9 26.6 1.7e-16 59.8 3.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OppC_N PF12911.2 AAS52059.1 - 0.052 12.9 0.5 0.052 12.9 0.3 2.7 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C HA2 PF04408.18 AAS52060.1 - 1.5e-19 69.9 0.0 3e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AAS52060.1 - 2.8e-16 59.3 0.0 6.7e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AAS52060.1 - 6.5e-12 45.1 0.0 3e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 AAS52060.1 - 1.8e-09 37.2 0.0 4.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AAS52060.1 - 1.4e-05 25.2 0.1 3.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AAS52060.1 - 0.00013 21.4 0.0 0.53 9.6 0.0 2.6 3 0 0 3 3 3 2 AAA-like domain AAA_19 PF13245.1 AAS52060.1 - 0.00064 19.4 1.4 0.0063 16.2 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain SRP54 PF00448.17 AAS52060.1 - 0.00087 18.7 0.1 0.0074 15.7 0.1 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 AAS52060.1 - 0.0026 17.2 0.1 0.014 14.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain Helicase_RecD PF05127.9 AAS52060.1 - 0.0031 17.1 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 Helicase AAA_29 PF13555.1 AAS52060.1 - 0.0039 16.6 0.0 0.009 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 AAS52060.1 - 0.007 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 AAS52060.1 - 0.0073 16.3 0.6 0.046 13.6 0.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 AAS52060.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 AAS52060.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 AAS52060.1 - 0.034 13.1 0.0 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 AAS52060.1 - 0.037 14.3 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 AAS52060.1 - 0.043 13.7 0.1 0.53 10.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 AAS52060.1 - 0.052 13.8 0.0 0.093 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 AAS52060.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF258 PF03193.11 AAS52060.1 - 0.089 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ResIII PF04851.10 AAS52060.1 - 0.1 12.4 0.0 2.9 7.6 0.0 2.1 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit SUR7 PF06687.7 AAS52061.1 - 4.2e-27 95.1 12.6 5.3e-27 94.7 8.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family CobD_Cbib PF03186.8 AAS52061.1 - 0.055 12.5 0.8 0.087 11.8 0.6 1.2 1 0 0 1 1 1 0 CobD/Cbib protein OAR PF03826.12 AAS52061.1 - 0.13 11.8 0.4 0.23 11.0 0.2 1.5 1 0 0 1 1 1 0 OAR domain DUF2721 PF11026.3 AAS52061.1 - 7 6.3 10.9 0.45 10.1 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Tht1 PF04163.7 AAS52063.2 - 3.5e-40 137.9 14.7 5.8e-34 117.4 0.0 2.1 1 1 1 2 2 2 2 Tht1-like nuclear fusion protein Apolipoprotein PF01442.13 AAS52063.2 - 2e-07 30.7 3.6 0.0034 16.9 0.1 2.6 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Fzo_mitofusin PF04799.8 AAS52063.2 - 0.00025 20.4 4.6 0.073 12.4 0.1 2.6 2 1 0 2 2 2 2 fzo-like conserved region Baculo_PEP_C PF04513.7 AAS52063.2 - 0.0018 18.1 19.1 0.031 14.1 1.0 4.0 2 1 3 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus Tektin PF03148.9 AAS52063.2 - 0.0069 14.9 3.9 0.039 12.4 0.2 2.2 2 0 0 2 2 2 1 Tektin family FliJ PF02050.11 AAS52063.2 - 0.012 15.6 0.8 7.8 6.5 0.3 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein APG17 PF04108.7 AAS52063.2 - 0.017 13.9 7.5 0.044 12.5 0.3 2.7 1 1 2 3 3 3 0 Autophagy protein Apg17 COG2 PF06148.6 AAS52063.2 - 0.017 14.9 6.0 0.55 10.1 0.8 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 KxDL PF10241.4 AAS52063.2 - 0.032 14.1 0.3 2.5 8.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein Prominin PF05478.6 AAS52063.2 - 0.035 11.6 11.2 0.42 8.0 7.9 2.1 1 1 0 1 1 1 0 Prominin Glutaredoxin2_C PF04399.8 AAS52063.2 - 0.041 13.4 2.2 0.43 10.1 0.0 3.1 4 0 0 4 4 3 0 Glutaredoxin 2, C terminal domain Taxilin PF09728.4 AAS52063.2 - 0.057 12.4 1.3 0.3 10.1 0.1 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.4 AAS52063.2 - 0.071 12.9 2.0 3.9 7.3 0.2 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin-6_N PF09177.6 AAS52063.2 - 0.094 13.1 4.4 4.5 7.7 0.2 2.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal ApoLp-III PF07464.6 AAS52063.2 - 0.1 12.5 2.8 3.1 7.8 0.1 2.5 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) AAA_13 PF13166.1 AAS52063.2 - 0.14 10.5 8.7 1.1 7.6 6.1 1.9 1 1 0 1 1 1 0 AAA domain DUF1664 PF07889.7 AAS52063.2 - 0.22 11.3 5.6 2.9 7.6 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) GP41 PF00517.12 AAS52063.2 - 0.28 10.7 9.7 0.029 13.9 2.2 2.6 2 2 1 3 3 3 0 Retroviral envelope protein FlaC_arch PF05377.6 AAS52063.2 - 0.32 10.9 7.0 0.34 10.8 0.8 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Nnf1 PF03980.9 AAS52063.2 - 0.41 10.6 4.8 1.6 8.7 0.1 2.8 2 1 0 2 2 2 0 Nnf1 BLOC1_2 PF10046.4 AAS52063.2 - 0.46 10.6 5.2 2.5 8.2 0.1 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 AAS52063.2 - 1.1 9.0 8.1 1.3 8.7 0.8 2.8 1 1 2 3 3 3 0 Laminin Domain II COG5 PF10392.4 AAS52063.2 - 1.1 9.2 12.7 1.8 8.5 0.3 4.1 2 1 3 5 5 4 0 Golgi transport complex subunit 5 SF-assemblin PF06705.6 AAS52063.2 - 1.2 8.1 7.7 2.4 7.2 0.7 2.6 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF948 PF06103.6 AAS52063.2 - 1.8 8.4 10.4 1.5 8.7 0.1 3.8 3 1 2 5 5 4 0 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.16 AAS52063.2 - 1.9 7.9 7.6 3.5 7.0 2.4 2.7 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TBPIP PF07106.8 AAS52063.2 - 3.1 7.3 7.8 8.9 5.8 0.2 2.9 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Apq12 PF12716.2 AAS52063.2 - 6.1 6.6 11.1 0.68 9.6 3.7 2.2 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis Endonuclease_NS PF01223.18 AAS52064.1 - 1.6e-59 201.0 0.0 1.8e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Kinesin PF00225.18 AAS52065.1 - 3.4e-101 338.3 0.0 5.9e-101 337.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain GOLGA2L5 PF15070.1 AAS52065.1 - 0.025 13.1 23.6 0.062 11.7 16.4 1.5 1 1 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DivIC PF04977.10 AAS52065.1 - 2 7.9 25.9 0.073 12.5 2.4 4.7 3 1 2 5 5 5 0 Septum formation initiator DUF904 PF06005.7 AAS52065.1 - 3.4 8.0 26.3 0.11 12.7 4.1 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 AAS52065.1 - 5.8 6.9 22.8 0.51 10.3 3.3 4.8 3 1 3 6 6 6 0 bZIP transcription factor DUF4337 PF14235.1 AAS52065.1 - 5.9 6.7 9.8 0.27 11.0 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) V-ATPase_C PF03223.10 AAS52066.1 - 4.8e-93 312.0 0.0 8.9e-92 307.8 0.0 1.9 1 1 0 1 1 1 1 V-ATPase subunit C EF1G PF00647.14 AAS52067.2 - 9.4e-46 153.9 0.0 1.8e-45 153.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 AAS52067.2 - 2.4e-07 30.6 0.0 2.4e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AAS52067.2 - 0.00028 20.9 0.0 0.002 18.2 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AAS52067.2 - 0.0059 16.4 0.1 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NARP1 PF12569.3 AAS52067.2 - 0.82 8.3 6.2 1.2 7.7 4.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SURF6 PF04935.7 AAS52068.1 - 5e-55 186.0 49.0 5e-55 186.0 33.9 2.9 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 AAS52068.1 - 2.7e-17 62.5 2.0 2.7e-17 62.5 1.4 6.4 5 1 1 6 6 6 1 60S ribosome biogenesis protein Rrp14 Motilin_ghrelin PF04644.7 AAS52068.1 - 0.56 10.0 0.0 0.56 10.0 0.0 6.9 7 1 1 8 8 8 0 Motilin/ghrelin DUF4144 PF13642.1 AAS52069.2 - 0.11 12.8 1.5 30 5.0 0.0 3.1 3 0 0 3 3 3 0 protein structure with unknown function PPR PF01535.15 AAS52069.2 - 1.4 9.1 4.3 38 4.5 0.0 4.7 6 0 0 6 6 6 0 PPR repeat PPR_2 PF13041.1 AAS52069.2 - 1.4 8.9 4.5 30 4.6 0.0 4.5 5 1 1 6 6 6 0 PPR repeat family TUG-UBL1 PF11470.3 AAS52070.2 - 1.3e-21 76.2 0.0 3.3e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 AAS52070.2 - 1e-13 51.0 0.2 3.2e-13 49.5 0.1 1.9 1 0 0 1 1 1 1 UBX domain RA PF00788.18 AAS52070.2 - 0.018 15.5 0.0 0.13 12.8 0.0 2.4 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Ank_2 PF12796.2 AAS52071.1 - 4.1e-21 75.1 0.5 3.8e-14 52.7 0.4 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AAS52071.1 - 1.9e-20 71.5 5.4 6.1e-06 25.7 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 AAS52071.1 - 1.2e-17 63.8 7.8 1.6e-08 34.7 0.2 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 AAS52071.1 - 1.3e-15 57.0 1.6 7.2e-07 29.2 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AAS52071.1 - 1.3e-13 49.7 3.6 0.027 14.6 0.1 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ldh_1_C PF02866.13 AAS52072.1 - 3.8e-48 163.5 0.0 5.3e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 AAS52072.1 - 1.7e-41 141.3 0.0 2.4e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 AAS52072.1 - 0.00011 20.9 0.0 0.00016 20.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 AAS52072.1 - 0.0063 15.5 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 AAS52072.1 - 0.032 14.2 0.4 0.12 12.3 0.3 1.9 1 1 0 1 1 1 0 NADH(P)-binding Glyco_hydro_4 PF02056.11 AAS52072.1 - 0.069 12.4 0.0 0.33 10.2 0.0 1.9 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase ParBc PF02195.13 AAS52073.1 - 8.3e-15 54.6 0.0 1e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain DUF2293 PF10056.4 AAS52073.1 - 0.17 11.8 1.4 1.5 8.8 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2293) G-alpha PF00503.15 AAS52074.1 - 1.9e-117 392.2 0.0 2.2e-117 392.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 AAS52074.1 - 1.6e-15 56.8 0.7 2.1e-10 40.1 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AAS52074.1 - 0.0001 21.5 0.2 0.012 14.7 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 AAS52074.1 - 0.00099 19.5 0.0 0.92 10.0 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 AAS52074.1 - 0.034 13.5 0.0 1 8.7 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AAS52074.1 - 0.036 14.0 0.0 9.2 6.2 0.0 2.8 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_29 PF13555.1 AAS52074.1 - 0.088 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 AAS52074.1 - 0.14 11.6 0.2 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Cyto_heme_lyase PF01265.12 AAS52075.2 - 6.4e-86 288.1 0.4 7.1e-86 287.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase zf-Tim10_DDP PF02953.10 AAS52076.1 - 7.8e-24 82.7 2.6 9.2e-24 82.5 1.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.4 AAS52076.1 - 0.0057 16.2 0.3 0.0083 15.7 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase DUF842 PF05811.8 AAS52076.1 - 0.007 15.8 2.5 0.0094 15.4 1.7 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Flavoprotein PF02441.14 AAS52077.1 - 5.4e-45 152.2 0.0 9.4e-45 151.4 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein DUF2457 PF10446.4 AAS52077.1 - 0.018 13.8 12.0 0.031 13.0 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.8 AAS52077.1 - 0.049 11.4 12.0 0.065 11.0 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.7 AAS52077.1 - 1.9 7.6 11.4 2.9 7.0 7.9 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 AAS52077.1 - 6.7 5.6 8.6 10 5.0 6.0 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 AAS52077.1 - 9.4 4.0 15.0 14 3.4 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family Ydc2-catalyt PF09159.5 AAS52078.2 - 8e-26 91.1 0.0 5.3e-25 88.4 0.0 2.2 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 AAS52078.2 - 0.16 11.8 0.0 5 6.9 0.0 2.5 2 1 0 2 2 2 0 Poxvirus A22 protein Peptidase_S24 PF00717.18 AAS52079.1 - 1e-07 31.5 0.1 1.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like FF PF01846.14 AAS52080.1 - 3.2e-38 129.4 22.9 2.3e-15 56.2 0.0 6.1 6 0 0 6 6 6 4 FF domain WW PF00397.21 AAS52080.1 - 6.3e-18 64.3 11.5 1.5e-10 40.7 2.2 2.9 2 0 0 2 2 2 2 WW domain PQQ PF01011.16 AAS52080.1 - 0.028 13.9 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_2 PF13360.1 AAS52080.1 - 0.032 13.6 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain Sod_Fe_C PF02777.13 AAS52081.2 - 6.5e-37 125.6 0.1 1.3e-36 124.6 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 AAS52081.2 - 7.3e-27 93.4 0.5 1.3e-26 92.7 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain p450 PF00067.17 AAS52083.1 - 2.4e-99 332.9 0.0 2.8e-99 332.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 AAS52084.1 - 7.2e-45 153.1 0.0 4.7e-44 150.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52084.1 - 5.4e-21 74.8 0.1 5.7e-18 64.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AAS52084.1 - 2.6e-06 26.5 0.0 1.4e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 AAS52084.1 - 0.085 11.6 4.5 0.23 10.2 1.1 2.1 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase SKI PF01202.17 AAS52085.1 - 1.3e-10 41.3 0.0 1.4e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.1 AAS52085.1 - 1.7e-10 41.3 0.3 3.4e-10 40.3 0.2 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AAS52085.1 - 6e-09 36.7 0.0 7.5e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AAS52085.1 - 2.5e-08 33.9 0.0 3.2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 AAS52085.1 - 7.2e-05 22.4 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.15 AAS52085.1 - 9.8e-05 22.0 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 AAS52085.1 - 0.00044 20.3 0.6 0.0028 17.7 0.4 2.1 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 AAS52085.1 - 0.0027 17.6 0.1 0.0083 16.0 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA PF00004.24 AAS52085.1 - 0.0072 16.5 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AAS52085.1 - 0.008 16.1 0.4 0.062 13.2 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 AAS52085.1 - 0.013 15.5 1.1 0.022 14.7 0.8 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 AAS52085.1 - 0.018 14.6 0.1 0.039 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 AAS52085.1 - 0.021 13.8 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CoaE PF01121.15 AAS52085.1 - 0.042 13.2 0.6 0.46 9.8 0.1 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase Zeta_toxin PF06414.7 AAS52085.1 - 0.052 12.6 0.2 0.095 11.7 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 AAS52085.1 - 0.061 13.0 0.2 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 AAS52085.1 - 0.062 12.8 0.4 0.11 12.0 0.3 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 AAS52085.1 - 0.1 11.4 0.6 0.22 10.4 0.3 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.1 AAS52085.1 - 0.3 10.4 2.0 0.81 9.0 1.4 2.1 1 1 0 1 1 1 0 AAA domain Thiolase_N PF00108.18 AAS52086.1 - 8e-104 346.2 6.6 1e-103 345.9 4.6 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AAS52086.1 - 1e-44 150.8 0.3 1e-44 150.8 0.2 2.2 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 AAS52086.1 - 2.7e-06 27.0 2.6 6.1e-06 25.8 1.8 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 AAS52086.1 - 0.0051 16.4 0.3 0.045 13.4 0.3 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Trm112p PF03966.11 AAS52087.1 - 2.7e-20 72.5 0.0 3.3e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein Pkinase PF00069.20 AAS52088.2 - 3.8e-74 249.1 0.0 5.8e-74 248.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52088.2 - 1.2e-31 109.7 0.0 1.4e-30 106.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS52088.2 - 9.7e-06 24.7 0.1 0.00019 20.5 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 AAS52088.2 - 0.016 14.3 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AAS52088.2 - 0.13 11.9 0.0 5.1 6.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family MutS_V PF00488.16 AAS52089.1 - 4.4e-77 258.6 0.1 1.7e-76 256.7 0.0 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 AAS52089.1 - 1e-34 120.0 0.8 1e-34 120.0 0.6 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 AAS52089.1 - 3.1e-30 104.5 0.5 8.8e-30 103.0 0.4 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 AAS52089.1 - 3.2e-07 30.5 0.0 7.3e-06 26.0 0.0 3.1 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 AAS52089.1 - 1.3e-06 28.4 0.0 4.8e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 MutS family domain IV AAA_22 PF13401.1 AAS52089.1 - 0.0047 17.0 0.1 0.019 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AAS52089.1 - 0.024 14.5 0.3 0.35 10.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain AF0941-like PF14591.1 AAS52089.1 - 0.025 14.6 0.4 0.08 13.0 0.0 2.1 2 0 0 2 2 2 0 AF0941-like UQ_con PF00179.21 AAS52090.1 - 1.3e-42 144.5 0.0 1.6e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 AAS52090.1 - 4.4e-28 96.6 1.7 6.9e-28 96.0 1.2 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 AAS52090.1 - 0.00044 20.0 0.0 0.00063 19.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA PF00627.26 AAS52090.1 - 0.00092 18.9 0.3 0.0028 17.4 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain RWD PF05773.17 AAS52090.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain CDC50 PF03381.10 AAS52091.1 - 1.9e-98 329.0 0.0 2.3e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CBF PF03914.12 AAS52092.2 - 1.1e-47 161.5 0.2 6.3e-47 159.0 0.1 2.1 2 0 0 2 2 2 1 CBF/Mak21 family Arrestin_C PF02752.17 AAS52093.1 - 3.1e-22 79.1 0.0 6.8e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 AAS52093.1 - 6.3e-10 39.0 0.0 1e-08 35.1 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 AAS52093.1 - 0.045 13.2 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like Pkinase PF00069.20 AAS52095.1 - 4.7e-57 193.0 0.0 1.1e-54 185.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52095.1 - 2.6e-21 75.8 0.0 1.6e-20 73.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS52095.1 - 0.017 14.1 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 AAS52095.1 - 0.061 13.0 0.0 0.53 9.9 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family WD40 PF00400.27 AAS52096.1 - 9.5e-35 117.2 14.5 7e-08 32.0 1.4 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 AAS52096.1 - 0.00032 18.9 3.1 0.15 10.1 0.2 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 V_ATPase_I PF01496.14 AAS52097.2 - 3.2e-284 944.5 0.6 3.6e-284 944.3 0.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family LCM PF04072.9 AAS52098.2 - 7.4e-25 87.5 0.0 9.4e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Methyltransf_25 PF13649.1 AAS52098.2 - 0.0034 17.6 0.1 0.0096 16.2 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain DUF3089 PF11288.3 AAS52098.2 - 0.098 11.8 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) TAFII28 PF04719.9 AAS52099.1 - 8.4e-22 76.7 0.9 3.7e-21 74.7 0.2 2.4 3 0 0 3 3 3 1 hTAFII28-like protein conserved region PIG-S PF10510.4 AAS52100.1 - 4.5e-142 474.3 5.4 5.4e-142 474.0 3.8 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Methyltransf_11 PF08241.7 AAS52101.2 - 5.8e-11 42.7 0.0 9.3e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AAS52101.2 - 4.8e-06 26.3 0.0 1e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AAS52101.2 - 1.3e-05 25.5 0.0 2.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS52101.2 - 2.7e-05 23.8 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS52101.2 - 0.00024 21.6 0.1 0.0004 20.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AAS52101.2 - 0.00046 20.4 0.0 0.00098 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UBA_4 PF14555.1 AAS52102.1 - 4.4e-12 45.3 0.0 9e-12 44.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 AAS52102.1 - 1.1e-09 38.2 0.2 8e-08 32.2 0.0 3.0 4 0 0 4 4 4 1 UBX domain Sigma70_r1_2 PF00140.15 AAS52102.1 - 0.081 12.6 2.3 0.19 11.4 1.6 1.7 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 LRS4 PF10422.4 AAS52102.1 - 1.7 7.9 8.7 2.2 7.5 5.5 1.5 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 APG6 PF04111.7 AAS52102.1 - 4.1 6.3 13.5 9 5.2 9.3 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 RRM_1 PF00076.17 AAS52103.1 - 4.3e-28 96.7 0.1 1.9e-16 59.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS52103.1 - 9.5e-17 60.7 0.0 4e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS52103.1 - 1.8e-14 53.3 0.0 9.4e-11 41.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AAS52103.1 - 0.066 12.9 0.0 10 5.9 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 M16C_assoc PF08367.6 AAS52104.2 - 2.9e-78 262.1 0.6 4.3e-78 261.5 0.4 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 AAS52104.2 - 3.6e-36 124.5 0.4 7.6e-21 74.6 0.0 3.6 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AAS52104.2 - 4.5e-08 32.9 0.0 6.1e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) EMP24_GP25L PF01105.19 AAS52105.1 - 1.5e-39 135.6 0.1 1.8e-39 135.3 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4164 PF13747.1 AAS52105.1 - 0.12 12.4 0.5 0.12 12.4 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Rad33 PF08730.5 AAS52106.1 - 1.7e-41 141.5 0.0 6.9e-40 136.2 0.0 2.0 1 1 0 1 1 1 1 Rad33 Spt5-NGN PF03439.8 AAS52107.2 - 3.1e-21 74.8 0.0 6.8e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 AAS52107.2 - 7.4e-17 61.7 17.6 7.4e-17 61.7 12.2 2.8 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 AAS52107.2 - 1.2e-13 50.1 3.1 0.0031 17.1 0.0 4.7 4 0 0 4 4 4 3 KOW motif CTD PF12815.2 AAS52107.2 - 0.00043 20.6 40.2 0.012 15.9 19.1 2.8 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 SPT6_acidic PF14632.1 AAS52107.2 - 4.1 7.6 47.1 0.034 14.3 16.4 2.6 1 1 1 2 2 2 0 Acidic N-terminal SPT6 Ribosomal_L33 PF00471.15 AAS52108.1 - 0.097 12.9 0.0 0.57 10.4 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L33 eIF3g PF12353.3 AAS52109.1 - 2e-42 144.0 0.1 3.1e-42 143.5 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 AAS52109.1 - 9.6e-12 44.3 0.0 1.6e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS52109.1 - 9.8e-10 38.2 0.0 1.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS52109.1 - 3e-07 30.1 0.0 7.3e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AAS52109.1 - 0.032 13.9 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCHC PF00098.18 AAS52109.1 - 0.099 12.6 0.9 0.16 11.9 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle Abhydrolase_3 PF07859.8 AAS52110.1 - 1.8e-09 37.5 0.0 2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AAS52110.1 - 1.8e-06 27.9 0.5 4.2e-06 26.8 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AAS52110.1 - 4.2e-05 23.3 0.0 5.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 AAS52110.1 - 0.00012 20.8 0.0 0.00019 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_1 PF00561.15 AAS52110.1 - 0.00026 20.5 0.0 0.00059 19.4 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 AAS52110.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 AAS52110.1 - 0.055 12.7 0.0 0.089 12.1 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.15 AAS52110.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain PCI PF01399.22 AAS52111.1 - 6.1e-10 39.3 0.0 3.2e-09 37.0 0.0 2.2 2 0 0 2 2 2 1 PCI domain Spo0A_C PF08769.6 AAS52111.1 - 0.00026 20.8 0.0 0.00079 19.2 0.0 1.8 2 0 0 2 2 2 1 Sporulation initiation factor Spo0A C terminal PX PF00787.19 AAS52112.1 - 7e-16 58.0 2.2 2.4e-15 56.3 0.0 2.6 3 0 0 3 3 3 1 PX domain Vps5 PF09325.5 AAS52112.1 - 0.0041 16.4 1.3 0.0041 16.4 0.9 1.9 2 0 0 2 2 2 1 Vps5 C terminal like Dynein_light PF01221.13 AAS52113.1 - 7.3e-36 122.0 0.1 7.7e-36 121.9 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 AAS52113.1 - 0.037 14.3 0.0 0.047 14.0 0.0 1.2 1 0 0 1 1 1 0 Ground-like domain AMPKBI PF04739.10 AAS52114.2 - 2.3e-27 94.8 0.0 5.4e-27 93.6 0.0 1.6 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain bZIP_1 PF00170.16 AAS52115.2 - 4.1e-06 26.6 11.0 6.5e-06 26.0 7.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AAS52115.2 - 1.2e-05 24.9 11.9 2e-05 24.3 8.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 AAS52115.2 - 0.089 13.0 9.9 0.16 12.2 6.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Macoilin PF09726.4 AAS52115.2 - 0.31 9.2 2.9 0.41 8.8 2.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Med21 PF11221.3 AAS52115.2 - 0.42 10.5 2.4 0.9 9.5 1.6 1.6 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Sterol_MT_C PF08498.5 AAS52116.1 - 4.8e-30 103.3 0.8 7.1e-30 102.7 0.6 1.2 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 AAS52116.1 - 1.1e-19 70.6 0.0 2e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS52116.1 - 1.9e-15 56.7 0.0 2.8e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AAS52116.1 - 4.1e-14 52.6 0.0 7.2e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AAS52116.1 - 2.5e-11 43.1 0.1 3.5e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 AAS52116.1 - 4.6e-11 42.9 0.0 1.4e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 AAS52116.1 - 9.5e-10 37.9 0.0 1.4e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 AAS52116.1 - 2.6e-09 37.4 0.0 5.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS52116.1 - 6.2e-09 36.4 0.0 1.4e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AAS52116.1 - 2e-05 24.6 0.0 7.7e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 AAS52116.1 - 6.4e-05 22.5 0.1 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.13 AAS52116.1 - 0.0046 16.1 0.0 0.008 15.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase RrnaAD PF00398.15 AAS52116.1 - 0.024 13.6 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 AAS52116.1 - 0.034 13.6 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Sugar_tr PF00083.19 AAS52117.2 - 1.7e-26 92.8 23.9 4.6e-23 81.5 16.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AAS52117.2 - 2.5e-16 59.3 41.7 5.5e-10 38.4 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 AAS52119.2 - 1.5e-06 27.9 10.0 1.5e-06 27.9 6.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 AAS52119.2 - 4 7.6 8.4 4.2 7.6 0.9 2.6 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region DUF2340 PF10209.4 AAS52121.1 - 6.2e-52 174.9 0.1 7.2e-52 174.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DUF676 PF05057.9 AAS52122.1 - 7.8e-44 149.5 0.0 1e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 AAS52122.1 - 5.4e-05 22.9 0.0 8.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AAS52122.1 - 0.00019 21.4 3.1 0.0012 18.7 2.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family TMEM191C PF15194.1 AAS52122.1 - 0.028 14.2 0.4 0.054 13.3 0.3 1.4 1 0 0 1 1 1 0 TMEM191C family PGAP1 PF07819.8 AAS52122.1 - 0.031 13.8 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Pkinase PF00069.20 AAS52124.1 - 2.2e-52 177.7 0.0 2.6e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52124.1 - 5.4e-16 58.4 0.0 7.9e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AAS52124.1 - 7.6e-07 29.0 0.0 2.5e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AAS52124.1 - 0.0055 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Alpha_kinase PF02816.13 AAS52124.1 - 0.064 12.9 0.1 2 8.0 0.0 2.3 2 0 0 2 2 2 0 Alpha-kinase family Ribosomal_L3 PF00297.17 AAS52126.2 - 3.6e-122 406.8 9.0 4.3e-122 406.5 6.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 PHD PF00628.24 AAS52127.1 - 2.7e-08 33.3 5.6 4.3e-08 32.7 3.9 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 AAS52127.1 - 0.13 12.5 0.2 1.8 8.8 0.1 2.3 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 AAS52127.1 - 0.13 12.3 2.5 0.23 11.6 1.7 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Cytochrom_C1 PF02167.10 AAS52128.2 - 1.4e-84 283.0 0.0 1.7e-84 282.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 AAS52128.2 - 0.00037 20.5 0.0 0.00083 19.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 AAS52128.2 - 0.00071 20.3 0.0 0.0021 18.8 0.0 1.9 1 0 0 1 1 1 1 Cytochrome c FlhD PF05247.8 AAS52129.2 - 0.11 12.5 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhD) Alg6_Alg8 PF03155.10 AAS52130.2 - 1.9e-142 475.4 30.9 2.2e-142 475.2 21.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Vps5 PF09325.5 AAS52131.1 - 7.2e-84 280.7 10.1 7.2e-84 280.7 7.0 1.5 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 AAS52131.1 - 2.8e-24 85.0 1.0 7.4e-24 83.7 0.1 2.1 2 0 0 2 2 2 1 PX domain V_ATPase_I PF01496.14 AAS52131.1 - 0.1 10.4 8.9 1.1 6.9 6.2 2.1 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Lactamase_B_2 PF12706.2 AAS52132.2 - 5.1e-38 130.5 0.2 8.9e-38 129.7 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 AAS52132.2 - 7.5e-21 73.3 0.0 1.6e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 AAS52132.2 - 4.8e-05 23.0 0.3 0.00011 21.9 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RabGAP-TBC PF00566.13 AAS52133.2 - 2e-49 168.0 1.2 3.7e-49 167.0 0.9 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain THF_DHG_CYH PF00763.18 AAS52134.1 - 1.8e-18 66.6 0.0 6.2e-18 64.9 0.0 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 AAS52134.1 - 3.2e-17 62.0 0.0 7e-11 41.4 0.0 2.8 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Brix PF04427.13 AAS52135.1 - 1.2e-34 119.6 0.2 1.6e-34 119.2 0.1 1.2 1 0 0 1 1 1 1 Brix domain Nucleoporin_N PF08801.6 AAS52136.2 - 3.7e-61 207.1 0.1 5.5e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 AAS52136.2 - 1e-59 202.6 14.3 1.6e-59 202.0 9.9 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF342 PF03961.8 AAS52136.2 - 0.027 12.9 0.2 0.043 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DASH_Dad2 PF08654.5 AAS52137.1 - 1.2e-35 121.5 0.2 1.4e-35 121.4 0.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad2 Reo_sigmaC PF04582.7 AAS52137.1 - 0.0059 15.8 0.5 0.0067 15.6 0.4 1.0 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DASH_Duo1 PF08651.5 AAS52137.1 - 0.018 14.6 1.2 0.023 14.2 0.8 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 COG5 PF10392.4 AAS52137.1 - 0.042 13.8 0.6 0.055 13.4 0.4 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DHC_N2 PF08393.8 AAS52137.1 - 0.05 12.1 0.2 0.056 11.9 0.2 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 Spc7 PF08317.6 AAS52137.1 - 0.073 11.7 0.2 0.09 11.4 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Matrilin_ccoil PF10393.4 AAS52137.1 - 0.14 11.5 0.4 0.23 10.8 0.3 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Shugoshin_N PF07558.6 AAS52138.2 - 5e-17 61.3 3.6 1.1e-16 60.2 2.5 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 AAS52138.2 - 3.1e-11 42.5 4.6 3.1e-11 42.5 3.2 2.3 2 0 0 2 2 2 1 Shugoshin C terminus Thymidylat_synt PF00303.14 AAS52139.1 - 3.4e-117 390.2 0.0 4e-117 390.0 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase Syntaxin-18_N PF10496.4 AAS52140.2 - 2.3e-21 75.4 0.6 6e-21 74.0 0.0 2.1 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 AAS52140.2 - 0.0014 18.2 6.5 0.0014 18.2 4.5 2.8 3 0 0 3 3 3 1 SNARE domain SecE PF00584.15 AAS52140.2 - 0.069 12.7 0.1 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex ERM PF00769.14 AAS52140.2 - 0.18 11.3 17.7 0.32 10.5 6.9 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF948 PF06103.6 AAS52140.2 - 1.1 9.1 13.7 2.5 8.0 4.9 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) GTP_EFTU PF00009.22 AAS52141.2 - 1.9e-43 148.0 0.0 3.3e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 AAS52141.2 - 1e-12 47.9 5.9 1e-12 47.9 4.1 2.1 2 0 0 2 2 2 1 HBS1 N-terminus MMR_HSR1 PF01926.18 AAS52141.2 - 3.4e-06 26.9 0.0 9.9e-06 25.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 AAS52141.2 - 5.3e-05 23.3 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Miro PF08477.8 AAS52141.2 - 0.015 15.7 0.0 0.058 13.8 0.0 2.1 1 1 0 1 1 1 0 Miro-like protein GTP_EFTU_D4 PF14578.1 AAS52141.2 - 0.032 13.8 0.1 0.081 12.5 0.1 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.20 AAS52141.2 - 0.035 14.2 0.2 0.077 13.1 0.1 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 G-alpha PF00503.15 AAS52141.2 - 0.043 12.4 0.0 0.089 11.4 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Arf PF00025.16 AAS52141.2 - 0.071 12.3 0.0 9.6 5.4 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family FeoB_N PF02421.13 AAS52141.2 - 0.083 12.1 0.1 1.2 8.4 0.0 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B MRP-L20 PF12824.2 AAS52143.1 - 1.3e-50 171.5 1.6 1.5e-50 171.3 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HA2 PF04408.18 AAS52144.1 - 1.7e-26 92.2 0.0 4.8e-26 90.7 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AAS52144.1 - 8.8e-21 73.8 0.0 3.3e-20 72.0 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AAS52144.1 - 2.3e-13 49.7 0.0 5.9e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AAS52144.1 - 3.2e-06 27.3 0.1 9.2e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 AAS52144.1 - 0.00023 20.6 0.2 0.00053 19.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 AAS52144.1 - 0.00081 19.0 0.0 0.0024 17.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 AAS52144.1 - 0.00084 19.2 0.1 0.42 10.4 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_23 PF13476.1 AAS52144.1 - 0.0017 18.7 0.5 0.024 14.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 AAS52144.1 - 0.0029 16.5 0.0 0.0087 14.9 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 AAS52144.1 - 0.0057 16.5 0.5 0.051 13.4 0.3 2.4 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 AAS52144.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain Sigma54_activ_2 PF14532.1 AAS52144.1 - 0.018 15.0 0.0 0.057 13.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 AAS52144.1 - 0.019 14.4 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 AAS52144.1 - 0.026 13.9 0.1 4.6 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 AAS52144.1 - 0.057 12.8 0.0 11 5.3 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.22 AAS52144.1 - 0.057 13.7 0.0 0.31 11.3 0.0 2.3 2 0 0 2 2 1 0 ABC transporter AAA_25 PF13481.1 AAS52144.1 - 0.078 12.3 0.0 0.38 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 AAS52144.1 - 0.082 11.7 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Kin17_mid PF10357.4 AAS52145.1 - 9e-44 148.1 6.1 1.5e-43 147.4 4.2 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 AAS52145.1 - 9.2e-08 32.0 2.4 2.7e-07 30.5 1.7 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AAS52145.1 - 1.3e-05 25.2 2.1 3.2e-05 23.9 1.5 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type TFIID_90kDa PF04494.10 AAS52145.1 - 0.003 17.6 0.4 0.003 17.6 0.3 1.9 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit zf-C2H2_2 PF12756.2 AAS52145.1 - 0.0087 16.1 0.2 0.0087 16.1 0.1 2.5 2 1 1 3 3 3 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 AAS52145.1 - 0.04 13.6 7.4 0.02 14.6 3.1 1.9 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) RNA_polI_A14 PF08203.6 AAS52145.1 - 0.089 13.0 0.7 5.2 7.3 0.0 2.7 1 1 1 2 2 2 0 Yeast RNA polymerase I subunit RPA14 zf-C2H2_4 PF13894.1 AAS52145.1 - 0.52 10.7 4.7 0.39 11.1 1.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 AAS52145.1 - 2.4 8.6 6.4 0.46 10.9 1.6 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2175 PF09943.4 AAS52145.1 - 5.7 7.0 6.8 7.8 6.6 0.5 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) SNARE_assoc PF09335.6 AAS52146.1 - 1.3e-15 57.7 6.3 1.3e-15 57.7 4.4 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein Oxidored_q1_N PF00662.15 AAS52146.1 - 0.022 14.3 0.2 0.19 11.3 0.0 2.5 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF4293 PF14126.1 AAS52146.1 - 0.095 12.6 0.4 0.095 12.6 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Spore_YtrH PF14034.1 AAS52146.1 - 0.74 9.7 5.5 0.71 9.8 0.1 3.0 2 1 1 3 3 3 0 Sporulation protein YtrH DUF2207 PF09972.4 AAS52146.1 - 2.2 6.7 9.3 0.21 10.1 3.0 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) BBP1_N PF15271.1 AAS52147.2 - 2 8.7 14.9 7.3 6.9 9.9 2.0 1 1 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein U3_snoRNA_assoc PF08297.6 AAS52148.2 - 7.5e-24 83.7 5.4 7.5e-24 83.7 3.7 2.4 2 0 0 2 2 2 1 U3 snoRNA associated AAA_11 PF13086.1 AAS52148.2 - 0.00084 18.9 1.1 0.0011 18.5 0.8 1.2 1 0 0 1 1 1 1 AAA domain SURF6 PF04935.7 AAS52148.2 - 0.0012 18.1 10.1 0.0018 17.5 7.0 1.3 1 0 0 1 1 1 1 Surfeit locus protein 6 Borrelia_P83 PF05262.6 AAS52148.2 - 0.4 8.8 15.0 0.48 8.6 10.4 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF515 PF04415.7 AAS52148.2 - 0.76 7.9 5.2 1.3 7.1 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF515) Zip PF02535.17 AAS52149.1 - 1.2e-25 90.2 11.5 2.6e-13 49.6 4.5 2.3 1 1 1 2 2 2 2 ZIP Zinc transporter TPR_11 PF13414.1 AAS52150.2 - 8.8e-11 41.2 1.5 2.6e-05 23.7 0.1 2.8 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 AAS52150.2 - 3.4e-08 32.7 5.9 0.00011 21.6 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box PF00646.28 AAS52150.2 - 5e-08 32.3 1.7 9.8e-05 21.9 0.1 3.6 3 0 0 3 3 3 2 F-box domain TPR_2 PF07719.12 AAS52150.2 - 9.7e-08 31.3 7.9 0.00017 21.2 0.4 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AAS52150.2 - 4.3e-07 29.7 4.3 0.053 13.4 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box-like PF12937.2 AAS52150.2 - 8.1e-05 22.2 5.3 0.00011 21.8 0.3 2.6 2 0 0 2 2 2 1 F-box-like TPR_9 PF13371.1 AAS52150.2 - 0.0002 21.1 0.4 0.0027 17.5 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.7 AAS52150.2 - 0.00068 19.3 0.3 1.8 8.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 AAS52150.2 - 0.0017 18.0 5.6 0.1 12.4 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 AAS52150.2 - 0.0049 16.5 0.7 0.0049 16.5 0.5 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 AAS52150.2 - 0.018 15.6 1.3 0.87 10.3 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 AAS52150.2 - 0.018 15.7 2.9 0.57 10.9 1.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 AAS52150.2 - 0.045 13.8 0.3 0.3 11.2 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 AAS52150.2 - 0.087 13.1 2.4 1.1 9.6 1.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.2 AAS52150.2 - 0.8 9.4 9.5 1.1 8.9 0.0 4.4 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF3336 PF11815.3 AAS52151.2 - 1.5e-40 138.0 8.9 2.9e-40 137.1 6.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 AAS52151.2 - 1.8e-27 96.6 0.0 3.3e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase LIM PF00412.17 AAS52152.1 - 2.8e-16 59.3 25.2 1.3e-09 37.9 6.6 2.4 2 0 0 2 2 2 2 LIM domain KCl_Cotrans_1 PF03522.10 AAS52152.1 - 0.021 14.3 0.3 0.021 14.3 0.2 3.2 3 0 0 3 3 3 0 K-Cl Co-transporter type 1 (KCC1) Whi5 PF08528.6 AAS52153.1 - 1.2e-10 40.7 0.3 2e-10 39.9 0.2 1.4 1 0 0 1 1 1 1 Whi5 like DELLA PF12041.3 AAS52154.1 - 0.051 13.2 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal Cofilin_ADF PF00241.15 AAS52155.1 - 2.9e-42 143.5 0.2 3.3e-42 143.3 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HTH_Tnp_Tc5 PF03221.11 AAS52156.1 - 9.9e-14 50.9 1.5 2e-13 49.9 0.1 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Utp14 PF04615.8 AAS52156.1 - 0.00092 17.5 3.2 0.0014 16.9 2.2 1.1 1 0 0 1 1 1 1 Utp14 protein CENP-B_N PF04218.8 AAS52156.1 - 0.058 12.8 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 AAS52156.1 - 0.078 12.5 0.3 0.33 10.5 0.2 2.1 1 1 0 1 1 1 0 Helix-turn-helix domain SET PF00856.23 AAS52157.2 - 2.6e-07 31.0 0.0 7.9e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 SET domain Phosphoesterase PF04185.9 AAS52158.1 - 9.7e-39 133.6 3.5 2.2e-36 125.8 2.0 2.5 1 1 1 2 2 2 2 Phosphoesterase family Cu-oxidase_3 PF07732.10 AAS52159.2 - 5.1e-37 126.2 2.3 9e-36 122.1 0.1 3.5 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 AAS52159.2 - 2.3e-36 124.3 9.2 4.5e-33 113.6 0.5 3.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 AAS52159.2 - 1.5e-31 109.4 0.4 5e-31 107.7 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase COX6B PF02297.12 AAS52160.1 - 8e-22 77.0 3.3 8.9e-22 76.9 2.3 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 AAS52160.1 - 0.098 12.6 0.2 0.2 11.6 0.2 1.6 1 1 0 1 1 1 0 CHCH domain UPF0203 PF05254.7 AAS52160.1 - 0.74 9.7 3.7 0.53 10.1 1.1 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) RIC1 PF07064.8 AAS52161.1 - 2.6e-11 43.4 0.3 2.9e-09 36.7 0.1 2.9 2 1 0 2 2 2 2 RIC1 WD40 PF00400.27 AAS52162.2 - 6.8e-19 66.9 12.3 1.2e-06 28.2 0.0 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 AAS52162.2 - 1.3e-17 63.4 0.0 2.6e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 AAS52162.2 - 0.0076 15.9 1.8 0.014 15.0 0.4 2.1 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Rrn6 PF10214.4 AAS52162.2 - 0.023 12.8 8.5 1.2 7.0 0.3 3.2 1 1 2 3 3 3 0 RNA polymerase I-specific transcription-initiation factor DUF814 PF05670.8 AAS52163.1 - 1.1e-20 73.2 0.2 2.5e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Meiotic_rec114 PF03525.9 AAS52164.1 - 2.2e-22 79.0 0.0 2.9e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Meiotic recombination protein rec114 CLTH PF10607.4 AAS52168.1 - 2.3e-23 82.5 7.4 3.8e-23 81.7 3.5 2.1 1 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain DUF3800 PF12686.2 AAS52168.1 - 0.019 14.5 0.4 0.019 14.5 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3800) GATA PF00320.22 AAS52169.1 - 5.3e-14 51.2 3.1 1e-13 50.3 2.1 1.5 1 0 0 1 1 1 1 GATA zinc finger DRMBL PF07522.9 AAS52170.1 - 4.4e-22 78.2 0.2 7.6e-22 77.4 0.2 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 AAS52170.1 - 4.1e-08 32.9 0.2 9.8e-08 31.7 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AAS52170.1 - 0.011 15.4 0.2 0.032 13.8 0.1 1.8 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Arf PF00025.16 AAS52171.2 - 1.4e-45 154.6 0.0 1.6e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 AAS52171.2 - 5e-12 45.2 0.4 9.2e-07 27.8 0.0 2.8 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 AAS52171.2 - 1.3e-09 37.5 0.0 1.6e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 AAS52171.2 - 1.8e-07 30.6 0.0 2.2e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 AAS52171.2 - 1.7e-06 27.5 0.0 0.00014 21.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AAS52171.2 - 2.5e-06 27.4 0.0 3.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 AAS52171.2 - 3.7e-05 23.0 0.0 5.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 AAS52171.2 - 8.1e-05 23.0 0.0 0.00011 22.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein cobW PF02492.14 AAS52171.2 - 0.0016 17.8 0.0 0.037 13.4 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Ldh_1_N PF00056.18 AAS52172.2 - 2.6e-42 143.9 0.0 4.3e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 AAS52172.2 - 6.9e-29 100.7 0.0 9e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 AAS52172.2 - 0.00042 19.1 0.0 0.00073 18.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.20 AAS52173.2 - 7.7e-60 202.2 0.0 9.4e-60 201.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52173.2 - 1.5e-25 89.7 0.0 2.1e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AAS52173.2 - 0.011 15.5 0.0 0.023 14.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 AAS52173.2 - 0.051 13.1 0.0 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase RICTOR_M PF14666.1 AAS52173.2 - 0.094 11.7 0.2 0.19 10.6 0.1 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain TPP_enzyme_N PF02776.13 AAS52174.2 - 5.5e-31 107.3 0.1 1.1e-30 106.3 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 AAS52174.2 - 6.2e-27 94.0 0.2 1.7e-26 92.6 0.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 AAS52174.2 - 1.2e-16 60.6 0.0 2.2e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TSA PF03249.8 AAS52174.2 - 0.029 12.9 0.0 0.042 12.3 0.0 1.1 1 0 0 1 1 1 0 Type specific antigen Herpes_UL37_2 PF07413.6 AAS52174.2 - 0.19 10.5 0.1 0.3 9.8 0.1 1.2 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 zf-C3HC4_2 PF13923.1 AAS52175.2 - 0.84 9.7 7.8 2.5 8.1 5.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_60s PF00428.14 AAS52176.2 - 7.5e-23 80.7 9.3 9.3e-23 80.4 6.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L13e PF01294.13 AAS52177.2 - 2.1e-72 242.3 5.6 2.9e-72 241.9 3.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_S9 PF00380.14 AAS52178.1 - 2.4e-39 134.3 0.3 2.7e-39 134.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Glyco_trans_1_3 PF13528.1 AAS52178.1 - 0.032 13.4 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 Spc7 PF08317.6 AAS52179.1 - 0.026 13.1 9.6 0.052 12.2 6.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DEAD PF00270.24 AAS52180.1 - 3.9e-35 120.8 0.2 1e-34 119.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS52180.1 - 6.2e-24 83.6 0.0 9.6e-23 79.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS52180.1 - 1.4e-05 25.0 0.0 3.5e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 AAS52180.1 - 0.053 12.5 0.1 0.16 10.9 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit HTH_psq PF05225.11 AAS52181.2 - 0.00023 20.6 0.0 0.0021 17.5 0.0 2.4 3 0 0 3 3 3 1 helix-turn-helix, Psq domain RDM PF11002.3 AAS52181.2 - 0.0017 17.9 0.2 0.034 13.8 0.0 2.6 3 0 0 3 3 3 1 RFPL defining motif (RDM) DUF455 PF04305.9 AAS52181.2 - 0.037 13.3 0.1 0.068 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF455) HTH_Tnp_Tc5 PF03221.11 AAS52181.2 - 0.14 11.9 0.7 0.31 10.8 0.2 1.8 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Pyr_redox_2 PF07992.9 AAS52182.1 - 9.2e-25 87.6 0.0 2.5e-15 56.9 0.0 3.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AAS52182.1 - 2.6e-12 46.9 0.0 3.9e-11 43.1 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AAS52182.1 - 0.0001 22.4 0.3 0.045 13.8 0.0 3.6 4 1 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase 4F5 PF04419.9 AAS52183.1 - 8.6e-09 35.9 9.2 8.6e-09 35.9 6.4 2.2 2 1 0 2 2 2 1 4F5 protein family Vac_Fusion PF02346.11 AAS52183.1 - 0.025 13.9 0.2 0.076 12.4 0.0 1.8 1 1 1 2 2 2 0 Chordopoxvirus fusion protein FAM110_N PF14161.1 AAS52183.1 - 0.27 11.5 2.7 0.3 11.3 1.7 1.3 1 1 0 1 1 1 0 Centrosome-associated N terminus IMD PF08397.6 AAS52183.1 - 4.5 6.5 8.6 4.8 6.4 6.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain DDRGK PF09756.4 AAS52183.1 - 5.9 6.2 14.6 6.6 6.0 10.1 1.0 1 0 0 1 1 1 0 DDRGK domain WD40 PF00400.27 AAS52184.1 - 2.8e-29 99.8 0.9 3.5e-08 33.0 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Gmad1 PF10647.4 AAS52184.1 - 0.00083 18.8 0.5 0.0026 17.1 0.2 1.8 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain eIF2A PF08662.6 AAS52184.1 - 0.0024 17.6 0.1 0.056 13.1 0.0 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A DLH PF01738.13 AAS52185.2 - 2.5e-20 72.7 0.0 2.8e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AAS52185.2 - 9e-07 28.7 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AAS52185.2 - 0.0043 16.3 0.3 0.024 13.8 0.2 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family B12-binding PF02310.14 AAS52185.2 - 0.12 12.3 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 B12 binding domain Peptidase_S15 PF02129.13 AAS52185.2 - 0.17 11.2 0.0 1.4 8.3 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) T5orf172 PF10544.4 AAS52186.2 - 3.5e-10 40.1 0.1 2e-07 31.3 0.1 2.4 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 AAS52186.2 - 5.5e-07 29.9 1.0 1.5e-05 25.3 0.7 2.6 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 Ribophorin_II PF05817.9 AAS52188.1 - 0.0048 15.1 0.1 0.0066 14.7 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Peptidase_S24 PF00717.18 AAS52189.2 - 1.8e-06 27.4 0.2 6.1e-06 25.7 0.0 1.9 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 AAS52189.2 - 0.00013 21.4 0.0 0.00021 20.8 0.0 1.4 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 adh_short PF00106.20 AAS52190.2 - 0.00021 21.2 0.5 0.58 10.0 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase LUC7 PF03194.10 AAS52191.1 - 9.4e-67 225.1 11.4 1.1e-66 224.9 7.9 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF4200 PF13863.1 AAS52191.1 - 0.00019 21.3 7.7 0.028 14.3 0.1 3.5 2 1 1 3 3 3 2 Domain of unknown function (DUF4200) Rho_Binding PF08912.6 AAS52191.1 - 0.011 15.9 4.1 0.035 14.4 0.1 2.9 3 0 0 3 3 3 0 Rho Binding Mod_r PF07200.8 AAS52191.1 - 0.019 14.9 7.1 0.12 12.2 1.7 2.8 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein SPAM PF02090.10 AAS52191.1 - 0.11 12.4 6.2 0.07 13.1 2.1 2.2 2 1 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein FlaC_arch PF05377.6 AAS52191.1 - 0.27 11.1 4.2 4.1 7.3 2.1 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Nup35_RRM PF05172.8 AAS52192.1 - 2.4e-33 113.9 0.0 4.7e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 AAS52192.1 - 0.00024 20.7 0.0 0.0019 17.9 0.0 2.2 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Vmethyltransf PF01660.12 AAS52192.1 - 0.035 12.7 0.2 0.059 12.0 0.1 1.3 1 0 0 1 1 1 0 Viral methyltransferase DUF2418 PF10332.4 AAS52193.2 - 1.1e-28 99.4 1.9 2.7e-28 98.1 1.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Prenyltrans PF00432.16 AAS52195.1 - 9.2e-37 124.2 6.8 2.7e-13 49.2 2.0 4.5 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AAS52195.1 - 3.4e-20 72.5 0.2 6.2e-11 42.6 0.0 3.3 1 1 2 3 3 3 3 Prenyltransferase-like UBX PF00789.15 AAS52196.2 - 8.5e-09 35.3 0.0 1.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain HlyD PF00529.15 AAS52196.2 - 4.5 6.4 8.9 6.6 5.9 6.1 1.2 1 0 0 1 1 1 0 HlyD family secretion protein SRP14 PF02290.10 AAS52197.2 - 3.6e-16 58.8 0.0 6.7e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Nodulin-like PF06813.8 AAS52198.2 - 4.6e-12 45.7 9.1 4.6e-12 45.7 6.3 3.1 4 0 0 4 4 4 1 Nodulin-like MFS_1 PF07690.11 AAS52198.2 - 7e-08 31.5 34.6 0.00021 20.1 13.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily WBP-1 PF11669.3 AAS52198.2 - 0.077 13.0 0.0 0.077 13.0 0.0 2.2 2 0 0 2 2 2 0 WW domain-binding protein 1 PMT PF02366.13 AAS52199.2 - 1.4e-73 247.3 12.6 1.4e-73 247.3 8.7 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 AAS52199.2 - 3.1e-59 199.7 1.2 4.5e-59 199.1 0.8 1.3 1 0 0 1 1 1 1 MIR domain PCI PF01399.22 AAS52200.1 - 8e-17 61.4 0.1 4e-16 59.2 0.0 2.2 2 0 0 2 2 2 1 PCI domain TPR_16 PF13432.1 AAS52200.1 - 0.00088 19.8 15.0 0.025 15.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Vps39_1 PF10366.4 AAS52200.1 - 0.0033 17.4 1.3 0.0033 17.4 0.9 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 TPR_12 PF13424.1 AAS52200.1 - 0.015 15.1 0.9 0.015 15.1 0.6 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 AAS52200.1 - 0.017 15.2 2.1 0.017 15.2 1.5 4.0 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AAS52200.1 - 0.063 13.0 5.0 2.5 8.0 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 AAS52200.1 - 0.25 11.3 0.2 0.25 11.3 0.1 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 AAS52200.1 - 0.29 11.0 7.5 0.51 10.2 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 AAS52200.1 - 0.71 10.4 0.1 0.71 10.4 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Rapamycin_bind PF08771.6 AAS52200.1 - 0.89 9.6 3.5 8.8 6.4 0.1 3.6 3 2 1 4 4 4 0 Rapamycin binding domain TPR_1 PF00515.23 AAS52200.1 - 1.1 8.9 5.1 5.2 6.8 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 AAS52200.1 - 1.1 8.6 6.2 2.6 7.4 0.3 2.5 1 1 1 2 2 2 0 Foie gras liver health family 1 zf-met PF12874.2 AAS52201.2 - 4.2e-06 26.7 0.4 7.8e-06 25.9 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AAS52201.2 - 1.1e-05 25.4 1.3 2.1e-05 24.5 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AAS52201.2 - 0.0079 16.0 0.8 0.017 14.9 0.5 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 AAS52201.2 - 0.041 13.9 1.7 0.066 13.3 1.2 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 AAS52201.2 - 0.099 13.0 1.0 0.23 11.8 0.7 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Ribosomal_S8 PF00410.14 AAS52203.1 - 3.1e-17 62.6 0.0 4e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Tropomyosin_1 PF12718.2 AAS52204.1 - 0.014 15.2 8.7 0.014 15.2 6.0 2.9 2 1 1 3 3 3 0 Tropomyosin like DUF3573 PF12097.3 AAS52204.1 - 0.15 10.6 2.1 0.24 9.9 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Baculo_PEP_C PF04513.7 AAS52204.1 - 0.15 11.8 5.6 0.23 11.2 3.9 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Striatin PF08232.7 AAS52204.1 - 0.35 11.1 23.8 0.36 11.1 8.0 2.7 2 1 1 3 3 3 0 Striatin family Seryl_tRNA_N PF02403.17 AAS52204.1 - 0.49 10.4 18.5 0.2 11.7 5.8 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Frigida PF07899.6 AAS52204.1 - 0.56 8.9 17.3 0.13 10.9 4.8 2.1 2 0 0 2 2 2 0 Frigida-like protein Prp31_C PF09785.4 AAS52204.1 - 0.63 10.4 7.1 0.17 12.3 0.9 2.3 2 0 0 2 2 2 0 Prp31 C terminal domain THOC7 PF05615.8 AAS52204.1 - 0.68 10.1 14.2 0.025 14.8 2.8 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 SlyX PF04102.7 AAS52204.1 - 1.5 9.2 19.3 0.075 13.4 5.6 2.9 2 1 1 3 3 3 0 SlyX DUF724 PF05266.9 AAS52204.1 - 1.8 8.1 18.5 1.7 8.2 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) GAS PF13851.1 AAS52204.1 - 2.3 7.3 22.5 0.2 10.8 5.6 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding COG2 PF06148.6 AAS52204.1 - 3.2 7.6 13.2 0.064 13.1 1.8 2.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.3 AAS52204.1 - 3.9 7.3 24.9 0.63 9.8 8.9 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding EzrA PF06160.7 AAS52204.1 - 4 5.5 17.5 0.054 11.6 5.8 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Spc7 PF08317.6 AAS52204.1 - 8.6 4.9 18.3 0.34 9.5 5.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein ArsA_ATPase PF02374.10 AAS52205.2 - 5.5e-115 383.6 0.0 6.3e-115 383.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 AAS52205.2 - 3.1e-12 46.3 0.0 4.7e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.13 AAS52205.2 - 0.00064 18.9 0.1 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.1 AAS52205.2 - 0.0037 17.1 0.0 0.025 14.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AAS52205.2 - 0.018 14.4 0.1 0.038 13.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 AAS52205.2 - 0.026 13.9 0.1 0.51 9.7 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF1644 PF07800.7 AAS52205.2 - 0.036 13.9 0.1 0.068 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) PhoH PF02562.11 AAS52205.2 - 0.069 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.7 AAS52205.2 - 0.088 11.8 0.0 0.48 9.4 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 AAS52205.2 - 0.18 10.6 0.1 0.37 9.6 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Glyoxalase PF00903.20 AAS52206.1 - 1.3e-26 93.0 0.1 1.1e-15 57.6 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 AAS52206.1 - 2.9e-22 79.3 0.0 3.6e-11 43.6 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 AAS52206.1 - 3.2e-10 39.9 0.0 1.1e-05 25.3 0.0 3.3 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 AAS52206.1 - 0.006 16.2 0.1 0.39 10.3 0.0 2.3 2 0 0 2 2 2 1 CppA N-terminal Glyoxalase_3 PF13468.1 AAS52206.1 - 0.018 14.9 0.0 0.34 10.7 0.0 2.3 1 1 0 2 2 2 0 Glyoxalase-like domain OB_NTP_bind PF07717.11 AAS52207.1 - 1e-16 60.7 0.0 2.1e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 AAS52207.1 - 4.1e-16 58.8 0.0 1.2e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AAS52207.1 - 8.6e-14 51.1 0.0 2e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AAS52207.1 - 3.6e-05 23.8 0.7 0.00018 21.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain DEAD PF00270.24 AAS52207.1 - 0.00013 21.5 0.0 0.0003 20.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 AAS52207.1 - 0.00018 20.5 0.0 0.00033 19.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 AAS52207.1 - 0.045 13.1 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 AAS52207.1 - 0.05 13.5 0.1 0.91 9.4 0.1 2.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 AAS52207.1 - 0.054 13.3 0.0 8 6.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AAS52207.1 - 0.078 12.7 0.1 0.26 11.0 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 AAS52207.1 - 0.11 12.7 0.2 0.66 10.2 0.0 2.4 2 1 0 2 2 2 0 ABC transporter DUF3830 PF12903.2 AAS52207.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) AAA_16 PF13191.1 AAS52207.1 - 0.51 10.3 10.2 1.8 8.4 0.1 3.5 2 1 2 4 4 4 0 AAA ATPase domain AAA_33 PF13671.1 AAS52207.1 - 0.58 10.0 5.4 3.4 7.5 0.0 3.0 2 1 0 2 2 2 0 AAA domain PRK PF00485.13 AAS52208.2 - 1.3e-62 210.8 0.0 1.9e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 AAS52208.2 - 2e-33 115.3 0.0 2.8e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 AAS52208.2 - 1.5e-08 35.5 0.0 3.7e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AAS52208.2 - 1.3e-07 31.9 0.0 4.5e-07 30.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 AAS52208.2 - 0.0011 18.1 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.7 AAS52208.2 - 0.0038 16.8 0.0 0.0078 15.8 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 AAS52208.2 - 0.03 14.1 0.0 0.09 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain CoaE PF01121.15 AAS52208.2 - 0.097 12.0 0.3 15 4.9 0.2 2.4 2 0 0 2 2 2 0 Dephospho-CoA kinase Rsbr_N PF08678.5 AAS52208.2 - 0.1 12.5 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Rsbr N terminal AAA_16 PF13191.1 AAS52208.2 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain SPX PF03105.14 AAS52209.2 - 8.6e-44 150.3 1.6 2e-43 149.1 1.1 1.6 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 AAS52209.2 - 1e-22 80.7 47.7 1.4e-22 80.2 33.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 AAS52209.2 - 2.2e-11 42.9 22.8 2.2e-11 42.9 15.8 2.2 1 1 1 2 2 2 1 Citrate transporter Glu_synthase PF01645.12 AAS52210.2 - 8.7e-157 521.7 0.1 3.5e-156 519.7 0.0 1.9 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 AAS52210.2 - 1.8e-136 454.5 0.0 3.3e-136 453.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 AAS52210.2 - 4e-118 393.8 0.0 3.7e-117 390.7 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 AAS52210.2 - 6.1e-59 198.4 0.6 1.3e-58 197.3 0.4 1.5 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 AAS52210.2 - 2.3e-24 85.1 0.1 4.4e-24 84.2 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 AAS52210.2 - 1.5e-14 54.3 0.0 5.5e-14 52.5 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AAS52210.2 - 7.7e-09 35.4 0.0 2.3e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AAS52210.2 - 4.8e-08 33.3 0.2 5.2e-06 26.7 0.0 3.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AAS52210.2 - 5.5e-07 28.8 0.4 1.9e-05 23.7 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AAS52210.2 - 1.8e-06 28.1 0.1 0.0067 16.5 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 AAS52210.2 - 8.7e-06 25.0 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 AAS52210.2 - 3.4e-05 22.4 1.2 4.6e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 AAS52210.2 - 0.00019 20.4 0.0 0.00034 19.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 AAS52210.2 - 0.00087 18.4 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 AAS52210.2 - 0.0015 17.7 0.0 0.0034 16.5 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 AAS52210.2 - 0.0033 16.5 0.0 0.0095 15.0 0.0 1.7 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.1 AAS52210.2 - 0.0081 16.3 0.5 0.92 9.8 0.0 2.8 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.17 AAS52210.2 - 0.0097 14.8 0.2 0.068 12.0 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A AdoHcyase_NAD PF00670.16 AAS52210.2 - 0.025 14.4 0.5 13 5.5 0.0 3.2 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GATase_6 PF13522.1 AAS52210.2 - 0.025 14.5 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain NAD_binding_9 PF13454.1 AAS52210.2 - 0.029 14.1 0.2 0.26 11.0 0.0 2.6 3 0 0 3 3 2 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 AAS52210.2 - 0.032 13.9 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMN_dh PF01070.13 AAS52210.2 - 0.054 12.3 1.0 0.35 9.6 0.6 2.3 2 0 0 2 2 2 0 FMN-dependent dehydrogenase AlaDh_PNT_C PF01262.16 AAS52210.2 - 0.069 12.7 0.0 0.78 9.2 0.0 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3602 PF12223.3 AAS52211.1 - 8.6e-22 77.3 8.8 1.1e-16 61.0 1.2 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Cnd3 PF12719.2 AAS52212.2 - 1.5e-101 339.3 6.8 7.3e-101 337.0 3.7 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 AAS52212.2 - 1.7e-09 37.8 0.1 1.4e-05 25.2 0.0 4.2 2 2 1 3 3 3 2 HEAT repeats HEAT PF02985.17 AAS52212.2 - 7.8e-08 31.7 2.1 0.6 10.3 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 AAS52212.2 - 0.043 14.3 1.8 11 6.6 0.0 4.8 4 1 2 6 6 6 0 HEAT-like repeat Pkinase PF00069.20 AAS52213.2 - 2.6e-44 151.3 0.0 4.4e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 AAS52213.2 - 5.3e-44 149.1 1.3 1.2e-43 148.0 0.9 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 AAS52213.2 - 2.9e-23 82.2 0.0 1.9e-21 76.3 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AAS52213.2 - 0.0014 17.7 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ PF01011.16 AAS52213.2 - 0.002 17.5 0.6 0.73 9.4 0.0 3.1 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.1 AAS52213.2 - 0.0065 15.9 0.0 0.043 13.2 0.0 2.1 1 1 0 1 1 1 1 PQQ-like domain Swi5 PF07061.6 AAS52214.1 - 1.1e-22 79.6 1.0 1.2e-22 79.4 0.7 1.1 1 0 0 1 1 1 1 Swi5 TPR_MLP1_2 PF07926.7 AAS52214.1 - 0.042 13.5 0.8 0.046 13.4 0.5 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.6 AAS52214.1 - 0.051 13.2 0.7 0.057 13.1 0.5 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Bap31 PF05529.7 AAS52214.1 - 0.075 12.4 0.6 0.11 11.9 0.4 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF3782 PF12644.2 AAS52214.1 - 0.1 12.4 0.2 0.14 11.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) BLOC1_2 PF10046.4 AAS52214.1 - 0.12 12.4 1.1 0.23 11.6 0.6 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.17 AAS52214.1 - 0.19 11.7 1.4 0.23 11.5 1.0 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain GRAM PF02893.15 AAS52215.2 - 1.1e-17 63.2 0.2 2.3e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 GRAM domain Skp1 PF01466.14 AAS52216.1 - 3.8e-36 122.9 0.6 6.4e-36 122.2 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 AAS52216.1 - 2.1e-13 50.1 0.0 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain Peroxin-3 PF04882.7 AAS52217.1 - 1.6e-122 409.3 0.1 1.8e-122 409.1 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DUF1191 PF06697.7 AAS52217.1 - 1.1 7.9 4.3 2.5 6.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Sas10_Utp3 PF04000.10 AAS52218.1 - 1.8e-07 31.2 0.0 2.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Alpha_TIF PF02232.10 AAS52218.1 - 0.16 10.7 0.3 0.18 10.5 0.2 1.1 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) Thioredoxin_7 PF13899.1 AAS52219.2 - 1.8e-18 66.3 0.1 3.3e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 AAS52219.2 - 1.3e-15 57.1 0.0 3.3e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 AAS52219.2 - 1.5e-12 46.8 0.0 3.1e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredox_DsbH PF03190.10 AAS52219.2 - 0.078 12.6 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF255 Peptidase_C13 PF01650.13 AAS52220.1 - 9.6e-48 162.7 2.0 1.3e-47 162.3 1.4 1.1 1 0 0 1 1 1 1 Peptidase C13 family Pkinase PF00069.20 AAS52221.1 - 8.5e-52 175.8 1.1 3.9e-51 173.7 0.8 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52221.1 - 4.5e-26 91.4 0.1 6e-25 87.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS52221.1 - 8e-08 31.5 0.0 1.6e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like ResIII PF04851.10 AAS52222.1 - 5.5e-22 78.4 0.3 2e-21 76.6 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AAS52222.1 - 3.7e-16 59.0 0.0 7.6e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS52222.1 - 8.5e-13 47.9 0.0 2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2075 PF09848.4 AAS52222.1 - 2.3e-05 23.5 0.0 5.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 AAS52222.1 - 9e-05 22.6 0.1 0.001 19.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain SNF2_N PF00176.18 AAS52222.1 - 0.00022 20.1 0.0 0.00054 18.8 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_11 PF13086.1 AAS52222.1 - 0.0048 16.5 1.5 0.087 12.3 0.1 2.6 2 1 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.9 AAS52222.1 - 0.0063 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain HTH_28 PF13518.1 AAS52222.1 - 0.043 13.8 0.0 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2887 PF11103.3 AAS52222.1 - 0.069 12.7 0.7 4.2 6.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2887) DUF2731 PF10806.3 AAS52223.2 - 7.9e-38 129.5 0.0 1.1e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2731) STE PF02200.11 AAS52224.2 - 2.3e-60 201.5 2.8 3.8e-60 200.8 1.9 1.3 1 0 0 1 1 1 1 STE like transcription factor Nucleoplasmin PF03066.10 AAS52224.2 - 2.9 7.3 9.4 1.5 8.3 1.9 2.3 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 AAS52224.2 - 7.2 6.9 13.2 22 5.3 4.5 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Tcf25 PF04910.9 AAS52225.2 - 1.8e-75 254.1 0.0 3.2e-75 253.3 0.0 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Spot_14 PF07084.7 AAS52225.2 - 0.31 10.9 5.3 1.7 8.5 0.1 2.5 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 Ipi1_N PF12333.3 AAS52226.2 - 5e-25 87.4 0.1 1.3e-24 86.1 0.1 1.7 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation RRM_1 PF00076.17 AAS52227.2 - 2.1e-45 152.1 0.0 1.6e-17 62.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS52227.2 - 1.8e-28 98.3 0.0 8.5e-10 38.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS52227.2 - 2.2e-17 62.6 0.0 2.3e-09 36.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AAS52227.2 - 0.00017 21.3 0.0 0.00065 19.5 0.1 2.0 2 1 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 AAS52227.2 - 0.011 15.5 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C2H2 PF00096.21 AAS52228.1 - 4.7e-08 32.9 13.0 0.00017 21.7 1.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AAS52228.1 - 0.00015 21.8 1.4 0.00015 21.8 0.9 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 AAS52228.1 - 0.00071 19.7 10.4 0.037 14.3 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AAS52228.1 - 0.0095 16.0 2.2 0.029 14.5 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AAS52228.1 - 0.081 13.1 0.5 0.081 13.1 0.4 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-BED PF02892.10 AAS52228.1 - 1.1 9.0 5.4 3.3 7.5 3.7 1.8 1 1 0 1 1 1 0 BED zinc finger zf-H2C2_5 PF13909.1 AAS52228.1 - 1.7 9.0 7.6 6.3 7.2 0.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain SNF2_N PF00176.18 AAS52229.2 - 3.2e-77 259.2 0.7 5.8e-77 258.4 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.8 AAS52229.2 - 4.7e-15 55.1 9.4 4.7e-15 55.1 6.5 2.6 1 1 1 2 2 2 2 HSA Helicase_C PF00271.26 AAS52229.2 - 3.5e-14 52.4 0.1 2.2e-13 49.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 AAS52229.2 - 2.9e-07 30.1 0.0 1.6e-06 27.7 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase NARP1 PF12569.3 AAS52230.2 - 3.2e-111 372.6 14.9 9.7e-84 281.9 1.8 3.5 2 2 1 4 4 4 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 AAS52230.2 - 1.8e-15 57.1 11.8 5.9e-05 23.6 0.0 6.3 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 AAS52230.2 - 7e-13 47.9 3.3 0.028 15.0 0.0 7.5 8 1 1 9 9 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 AAS52230.2 - 8.2e-13 47.2 17.0 0.01 15.6 0.0 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 AAS52230.2 - 2e-11 43.3 17.0 0.00045 19.8 0.1 5.9 7 0 0 7 7 7 4 TPR repeat Apc3 PF12895.2 AAS52230.2 - 8.8e-09 35.3 9.7 0.00093 19.2 0.0 5.6 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 AAS52230.2 - 8.3e-07 29.2 4.3 1.9 8.8 0.0 6.0 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 AAS52230.2 - 1.6e-05 24.2 11.1 0.2 11.3 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 AAS52230.2 - 4.6e-05 23.2 17.5 0.64 9.9 0.0 6.3 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 AAS52230.2 - 0.00092 19.2 7.2 13 6.2 0.0 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AAS52230.2 - 0.0043 16.8 4.8 0.19 11.6 0.0 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat SPO22 PF08631.5 AAS52230.2 - 0.013 14.6 0.8 4.7 6.1 0.0 3.3 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like Sel1 PF08238.7 AAS52230.2 - 0.024 15.2 0.6 0.51 11.0 0.0 3.5 3 0 0 3 3 3 0 Sel1 repeat TPR_6 PF13174.1 AAS52230.2 - 0.063 13.7 9.9 23 5.7 0.0 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 AAS52230.2 - 0.07 13.0 0.4 0.5 10.3 0.0 2.8 3 0 0 3 3 1 0 Tetratricopeptide repeat PaaX_C PF08223.6 AAS52230.2 - 0.098 12.3 1.9 0.11 12.1 0.2 1.9 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain HrcA_DNA-bdg PF03444.10 AAS52230.2 - 0.11 11.9 0.6 0.93 8.9 0.1 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding TPR_7 PF13176.1 AAS52230.2 - 1 9.3 8.9 2.5 8.1 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 AAS52230.2 - 1.7 8.5 16.1 17 5.4 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat NAD_Gly3P_dh_N PF01210.18 AAS52231.1 - 2.6e-52 176.6 0.0 5.9e-52 175.5 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 AAS52231.1 - 1e-47 161.5 0.0 1.6e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 AAS52231.1 - 0.018 15.4 0.0 9.8 6.6 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 AAS52231.1 - 0.08 13.2 0.1 0.46 10.7 0.1 2.2 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF21 PF01595.15 AAS52232.2 - 5.8e-32 110.4 0.1 1e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 AAS52232.2 - 2.9e-05 23.7 0.0 0.11 12.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain T4_Gp59_C PF08994.5 AAS52232.2 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term Pkinase PF00069.20 AAS52233.2 - 1e-58 198.5 0.0 1.6e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52233.2 - 6.7e-25 87.6 0.0 1e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS52233.2 - 0.00016 20.7 0.0 0.00034 19.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 AAS52233.2 - 0.0027 17.4 0.2 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pribosyl_synth PF14572.1 AAS52234.2 - 6.1e-39 133.6 0.6 1e-38 132.8 0.1 1.7 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 AAS52234.2 - 2.9e-36 123.7 0.9 2.4e-35 120.7 0.0 2.6 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 AAS52234.2 - 1.1e-11 44.4 0.0 2.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AAS52234.2 - 0.0077 15.4 0.2 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Adap_comp_sub PF00928.16 AAS52235.2 - 3.3e-79 265.6 0.1 4.1e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AAS52235.2 - 0.066 12.9 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Clathrin adaptor complex small chain Actin PF00022.14 AAS52236.1 - 3e-114 381.4 0.0 3.5e-114 381.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AAS52236.1 - 0.0034 16.0 0.0 0.021 13.4 0.0 2.1 1 1 0 1 1 1 1 MreB/Mbl protein Pkinase PF00069.20 AAS52237.2 - 4.4e-51 173.5 0.0 9.4e-51 172.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52237.2 - 7.7e-23 80.8 0.1 4.3e-21 75.1 0.1 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 AAS52237.2 - 0.00069 19.4 0.0 0.79 9.4 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 AAS52237.2 - 0.0023 17.3 0.3 0.0054 16.0 0.2 1.6 1 0 0 1 1 1 1 RIO1 family ASF1_hist_chap PF04729.8 AAS52240.2 - 5.4e-66 220.9 0.1 7.3e-66 220.5 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF1510 PF07423.6 AAS52240.2 - 0.11 11.8 28.2 0.15 11.3 19.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BTV_NS2 PF04514.7 AAS52240.2 - 6.5 5.5 18.9 9.5 4.9 13.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2201_N PF13203.1 AAS52240.2 - 7.3 5.6 9.7 8.5 5.4 6.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Mg_trans_NIPA PF05653.9 AAS52241.1 - 3.7e-14 52.4 7.8 6.1e-08 31.9 0.1 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA Multi_Drug_Res PF00893.14 AAS52241.1 - 7.9 7.0 10.6 0.28 11.6 1.2 2.6 2 0 0 2 2 2 0 Small Multidrug Resistance protein SUN PF03856.8 AAS52242.1 - 1.5e-101 338.9 14.8 2.1e-101 338.4 10.2 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) zf-MYND PF01753.13 AAS52242.1 - 0.061 13.2 1.9 0.14 12.0 1.3 1.5 1 0 0 1 1 1 0 MYND finger His_Phos_1 PF00300.17 AAS52243.1 - 2.8e-28 98.9 0.1 3.5e-28 98.6 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peripla_BP_3 PF13377.1 AAS52243.1 - 0.072 13.0 0.1 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding protein-like domain Lectin_leg-like PF03388.8 AAS52244.2 - 9.8e-12 44.4 0.0 5.4e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Legume-like lectin family Lectin_legB PF00139.14 AAS52244.2 - 2.9e-05 23.5 0.0 6.8e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Legume lectin domain Pho86 PF11124.3 AAS52245.2 - 1.1e-85 287.2 0.4 1.3e-85 287.1 0.3 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 DTHCT PF08070.6 AAS52246.2 - 2.1 9.0 0.0 2.1 9.0 0.0 2.8 2 1 1 3 3 3 0 DTHCT (NUC029) region Myosin_HC-like PF07058.6 AAS52246.2 - 2.4 7.1 4.7 4.9 6.1 3.3 1.5 1 1 0 1 1 1 0 Myosin II heavy chain-like Glyco_hydro_28 PF00295.12 AAS52247.1 - 2.1e-80 270.1 9.7 2.5e-80 269.9 6.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 AAS52247.1 - 0.00014 21.6 23.2 0.00087 19.0 7.1 2.8 2 1 1 3 3 3 2 Right handed beta helix region Pam17 PF08566.5 AAS52248.1 - 1.7e-70 236.2 0.0 2e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 PRF PF06875.6 AAS52248.1 - 0.099 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF CRT10 PF08728.5 AAS52249.2 - 7.2e-268 890.3 0.0 8.2e-268 890.1 0.0 1.0 1 0 0 1 1 1 1 CRT10 MFS_1 PF07690.11 AAS52250.1 - 1.3e-35 122.7 29.6 1.9e-35 122.2 20.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PspB PF06667.7 AAS52250.1 - 0.096 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Phage shock protein B DUF3169 PF11368.3 AAS52250.1 - 0.24 10.5 0.0 0.24 10.5 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3169) WTF PF03303.8 AAS52250.1 - 7.7 5.8 10.9 1.1 8.6 2.5 2.4 3 0 0 3 3 3 0 WTF protein Raptor_N PF14538.1 AAS52251.2 - 2.5e-67 225.5 6.6 3.6e-67 225.0 0.0 2.8 3 0 0 3 3 3 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 AAS52251.2 - 2e-08 33.7 9.4 0.39 10.6 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 AAS52251.2 - 4.4e-05 23.2 0.0 0.001 18.8 0.0 3.0 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.17 AAS52251.2 - 0.00056 19.7 1.1 0.33 11.1 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 AAS52251.2 - 0.062 13.5 0.0 1 9.6 0.0 2.9 2 0 0 2 2 2 0 HEAT repeats Elong_Iki1 PF10483.4 AAS52252.1 - 1.8e-86 290.0 0.0 2e-86 289.8 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Gpi16 PF04113.9 AAS52253.2 - 5.6e-191 635.4 0.0 7.5e-191 634.9 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component HEAT_2 PF13646.1 AAS52254.2 - 2.6e-10 40.4 2.9 0.0088 16.3 0.0 7.6 3 2 6 9 9 9 3 HEAT repeats HEAT_EZ PF13513.1 AAS52254.2 - 8.8e-08 32.4 5.0 0.58 10.7 0.0 9.3 9 2 1 10 10 10 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 AAS52254.2 - 6.3e-07 29.7 0.1 0.3 11.4 0.0 4.5 4 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 AAS52254.2 - 4.8e-06 26.2 14.9 0.096 12.8 0.0 9.1 11 0 0 11 11 11 2 HEAT repeat Adaptin_N PF01602.15 AAS52254.2 - 0.00063 18.1 1.5 0.24 9.7 0.8 3.1 1 1 0 1 1 1 1 Adaptin N terminal region Adaptin_N PF01602.15 AAS52255.2 - 2.4e-89 300.0 13.1 2.9e-89 299.7 9.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 AAS52255.2 - 3e-12 45.5 8.4 0.0056 16.6 0.0 6.8 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 AAS52255.2 - 9.2e-11 41.8 5.0 4.7e-07 30.0 0.2 4.6 4 1 0 4 4 4 2 HEAT repeats Cnd1 PF12717.2 AAS52255.2 - 3.6e-08 33.4 12.0 9.5e-07 28.8 0.9 5.0 3 2 3 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 AAS52255.2 - 3.2e-05 24.2 4.5 2.1 8.9 0.1 4.5 3 2 2 5 5 5 2 HEAT-like repeat Cohesin_HEAT PF12765.2 AAS52255.2 - 0.0041 17.0 2.7 1.9 8.5 0.1 3.8 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion RasGEF_N_2 PF14663.1 AAS52255.2 - 0.0056 16.6 1.9 1.2 9.0 0.1 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RTTN_N PF14726.1 AAS52255.2 - 0.0082 16.6 0.2 4.1 8.0 0.1 3.2 2 0 0 2 2 2 1 Rotatin, an armadillo repeat protein, centriole functioning RUN PF02759.14 AAS52255.2 - 0.041 13.6 0.0 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 RUN domain MFS_1 PF07690.11 AAS52256.1 - 1.9e-33 115.6 19.8 1.9e-33 115.6 13.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 AAS52257.1 - 1.8e-27 96.0 35.4 1.8e-26 92.6 21.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ssl1 PF04056.9 AAS52258.1 - 5.1e-87 290.4 0.1 6.8e-87 290.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 AAS52258.1 - 8.4e-22 76.9 14.9 8.4e-22 76.9 10.3 2.6 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 AAS52258.1 - 7e-12 45.7 0.0 9.8e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 AAS52258.1 - 0.00078 19.2 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Taeniidae_ag PF05596.6 AAS52258.1 - 0.04 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Taeniidae antigen Myc_N PF01056.13 AAS52258.1 - 0.056 12.6 5.4 0.092 11.8 3.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PBP1_TM PF14812.1 AAS52258.1 - 1.4 9.2 8.3 3 8.2 5.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 AAS52258.1 - 2 7.9 7.1 3.5 7.1 4.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Tfb4 PF03850.9 AAS52258.1 - 8.9 5.4 10.1 8.5 5.5 5.7 1.9 2 0 0 2 2 2 0 Transcription factor Tfb4 Glyco_hydro_92 PF07971.7 AAS52259.3 - 5.8e-140 467.2 0.1 7.9e-140 466.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 CMS1 PF14617.1 AAS52261.1 - 1e-19 70.5 8.4 3e-13 49.4 4.7 2.8 2 1 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit VitD-bind_III PF09164.5 AAS52261.1 - 0.0028 17.2 0.8 0.036 13.6 0.0 2.5 1 1 1 2 2 2 1 Vitamin D binding protein, domain III FliJ PF02050.11 AAS52261.1 - 0.027 14.5 4.8 0.06 13.4 3.4 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein PLRV_ORF5 PF01690.12 AAS52261.1 - 0.3 10.1 5.5 0.42 9.7 3.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Adaptin_N PF01602.15 AAS52262.2 - 4.9e-91 305.6 16.5 6.2e-91 305.3 11.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 AAS52262.2 - 1.9e-07 31.2 0.1 0.05 13.8 0.0 3.9 2 1 2 4 4 4 3 HEAT repeats Response_reg PF00072.19 AAS52263.2 - 9.9e-22 77.0 0.0 3.1e-13 49.7 0.0 2.3 1 1 1 2 2 2 2 Response regulator receiver domain SMC_Nse1 PF07574.8 AAS52264.2 - 3.2e-63 212.9 0.0 4e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 AAS52264.2 - 1.7e-12 47.1 11.5 3.5e-12 46.1 8.0 1.6 1 0 0 1 1 1 1 RING-like domain PhnA_Zn_Ribbon PF08274.7 AAS52264.2 - 1.1 9.0 5.3 14 5.6 0.9 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DnaJ PF00226.26 AAS52265.1 - 5.8e-06 25.9 0.1 8.1e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 AAS52265.1 - 0.00017 21.3 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Pam16 Ribosomal_L24e PF01246.15 AAS52266.1 - 2.4e-29 101.0 1.7 5.4e-29 99.8 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 AAS52266.1 - 0.26 10.9 2.7 0.54 9.9 1.9 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif AIF-MLS PF14962.1 AAS52266.1 - 0.95 9.0 6.8 1.2 8.7 4.7 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence GCD14 PF08704.5 AAS52267.2 - 6.4e-06 25.8 0.0 0.00089 18.8 0.0 2.7 3 0 0 3 3 3 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.1 AAS52267.2 - 0.04 14.7 0.0 0.069 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 AAS52267.2 - 0.042 13.4 0.0 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_L28e PF01778.12 AAS52269.1 - 9.1e-33 113.1 1.8 1.9e-32 112.1 1.3 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 AAS52269.1 - 1.6e-30 105.1 12.7 1.6e-30 105.1 8.8 2.7 1 1 1 2 2 2 1 Mak16 protein C-terminal region Ribosomal_L24e PF01246.15 AAS52269.1 - 0.013 15.3 0.1 0.036 13.9 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L24e HAD PF12710.2 AAS52270.2 - 1.5e-18 67.6 0.0 4.5e-18 66.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 AAS52270.2 - 1.4e-16 60.2 0.3 2.6e-16 59.3 0.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AAS52270.2 - 1.6e-13 51.6 1.3 2.8e-10 40.9 0.7 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AAS52270.2 - 2.3e-09 37.1 0.0 6.1e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AAS52270.2 - 0.00039 20.0 0.0 0.0098 15.4 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AAS52270.2 - 0.061 13.5 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Aldedh PF00171.17 AAS52271.2 - 5.2e-11 41.5 1.7 2.8e-09 35.8 0.3 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Saw1 PF11561.3 AAS52272.2 - 9.4e-75 250.7 0.0 1.1e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 Single strand annealing-weakened 1 Myosin_head PF00063.16 AAS52274.1 - 4.3e-261 867.8 6.7 4.3e-261 867.8 4.6 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 AAS52274.1 - 3.7e-34 116.7 2.2 1.4e-33 114.8 1.5 2.1 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 AAS52274.1 - 1.9e-10 39.4 14.4 0.015 14.9 0.1 6.1 6 0 0 6 6 6 4 IQ calmodulin-binding motif Myosin_N PF02736.14 AAS52274.1 - 0.00012 21.7 0.1 0.00033 20.2 0.1 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 AAS52274.1 - 0.00033 20.7 1.0 0.0016 18.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DBI_PRT PF02277.12 AAS52274.1 - 0.023 13.8 0.1 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyltransferase Reo_sigmaC PF04582.7 AAS52274.1 - 0.053 12.7 13.2 0.16 11.0 6.8 2.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein AAA_19 PF13245.1 AAS52274.1 - 0.077 12.7 0.1 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain DUF972 PF06156.8 AAS52274.1 - 0.087 13.1 19.5 0.3 11.4 0.7 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF972) ABC_tran PF00005.22 AAS52274.1 - 0.13 12.5 0.0 0.13 12.5 0.0 2.9 2 1 0 2 2 1 0 ABC transporter IncA PF04156.9 AAS52274.1 - 0.15 11.6 29.6 0.047 13.2 11.4 2.7 1 1 1 2 2 2 0 IncA protein AAA_16 PF13191.1 AAS52274.1 - 0.18 11.7 3.0 0.35 10.8 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain ADIP PF11559.3 AAS52274.1 - 1.2 9.0 28.9 0.031 14.1 5.7 3.5 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 AAS52274.1 - 1.2 9.0 17.3 0.16 11.8 0.6 4.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 AAS52274.1 - 1.4 8.4 30.0 0.42 10.1 0.7 5.6 4 1 1 5 5 5 0 Septum formation initiator Synaptobrevin PF00957.16 AAS52275.1 - 2.7e-32 110.2 1.2 3.1e-32 110.0 0.8 1.0 1 0 0 1 1 1 1 Synaptobrevin Phospholamban PF04272.9 AAS52275.1 - 0.1 12.0 1.6 0.16 11.4 1.1 1.3 1 0 0 1 1 1 0 Phospholamban OppC_N PF12911.2 AAS52275.1 - 6.7 6.1 6.3 16 4.9 4.3 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DNA_pol_A PF00476.15 AAS52277.1 - 1.4e-98 329.9 0.0 2.1e-98 329.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DUF1454 PF07305.7 AAS52277.1 - 0.00081 18.5 0.3 0.012 14.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1454) vATP-synt_E PF01991.13 AAS52278.2 - 3.4e-58 196.2 11.5 3.9e-58 195.9 8.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Vps35 PF03635.12 AAS52278.2 - 0.0019 16.4 1.8 0.0021 16.3 1.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 GLTP PF08718.6 AAS52278.2 - 0.044 13.8 1.0 0.07 13.1 0.7 1.3 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) Microtub_bind PF13931.1 AAS52278.2 - 0.3 11.2 7.9 2.7 8.1 4.1 2.2 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding FAM176 PF14851.1 AAS52278.2 - 0.45 10.1 4.6 0.67 9.6 3.2 1.2 1 0 0 1 1 1 0 FAM176 family Phlebovirus_NSM PF07246.6 AAS52278.2 - 0.99 8.5 6.7 1.6 7.8 4.7 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CorA PF01544.13 AAS52279.1 - 2.4e-07 30.0 1.3 5.4e-07 28.9 0.9 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SKIP_SNW PF02731.10 AAS52281.1 - 8.3e-56 187.8 9.1 8.3e-56 187.8 6.3 1.7 2 0 0 2 2 2 1 SKIP/SNW domain Asp-B-Hydro_N PF05279.6 AAS52281.1 - 4.5 7.0 13.9 0.35 10.6 6.1 1.8 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region RNase_P_Rpp14 PF01900.14 AAS52282.1 - 1.9e-35 121.0 0.3 2.3e-35 120.7 0.2 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family tRNA-synt_2c PF01411.14 AAS52283.1 - 1.3e-222 740.0 0.5 2.8e-222 738.9 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 AAS52283.1 - 1e-19 70.1 0.3 2.6e-19 68.8 0.2 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 AAS52283.1 - 4.5e-08 32.6 2.2 1.2e-07 31.3 1.5 1.8 1 0 0 1 1 1 1 DHHA1 domain UDP-g_GGTase PF06427.6 AAS52284.1 - 6.5e-07 28.8 0.0 2.3e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Fungal_trans PF04082.13 AAS52285.2 - 3.8e-35 121.0 3.1 8e-35 119.9 2.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS52285.2 - 4e-08 33.0 11.5 8.2e-08 32.0 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIRM PF04433.12 AAS52286.2 - 3.1e-13 49.6 0.0 4.8e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 SWIRM domain Mis12 PF05859.7 AAS52287.1 - 9.1e-47 158.4 0.1 1.6e-46 157.7 0.1 1.4 1 0 0 1 1 1 1 Mis12 protein DUF3085 PF11284.3 AAS52287.1 - 0.028 14.6 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) CHDCT2 PF08074.6 AAS52287.1 - 0.031 14.0 0.1 0.045 13.4 0.1 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain PK PF00224.16 AAS52288.1 - 1.6e-167 556.4 0.5 2e-167 556.1 0.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 AAS52288.1 - 3e-29 100.9 0.1 7.8e-29 99.6 0.1 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 AAS52288.1 - 2.4e-05 23.3 0.3 0.00011 21.2 0.1 1.9 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMS PF00817.15 AAS52289.1 - 1.1e-29 103.1 0.1 4e-29 101.3 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 AAS52289.1 - 2.1e-11 43.8 0.0 1.8e-10 40.8 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 AAS52289.1 - 1.2e-05 25.3 0.0 3.3e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AAS52289.1 - 3e-05 23.7 0.7 6.7e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 twin BRCT domain HHH PF00633.18 AAS52289.1 - 0.068 12.9 0.2 0.37 10.6 0.1 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif IMS_HHH PF11798.3 AAS52289.1 - 0.11 12.5 0.0 0.52 10.4 0.0 2.1 1 0 0 1 1 1 0 IMS family HHH motif HLH PF00010.21 AAS52290.1 - 1.9e-20 72.3 0.2 3.2e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TGS PF02824.16 AAS52292.1 - 4.1e-21 74.5 0.0 7.4e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 AAS52292.1 - 5e-17 61.9 0.0 1.2e-16 60.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AAS52292.1 - 5.8e-09 35.4 0.1 1.4e-08 34.1 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AAS52292.1 - 0.0015 18.3 0.3 1 9.1 0.0 2.3 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 AAS52292.1 - 0.0052 15.6 0.1 0.012 14.3 0.1 1.6 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 AAS52292.1 - 0.015 15.7 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Arf PF00025.16 AAS52292.1 - 0.11 11.6 0.1 1.9 7.6 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.22 AAS52293.2 - 7.1e-33 113.6 0.0 7.1e-33 113.6 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 AAS52293.2 - 8.3e-21 73.9 0.0 2.3e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 AAS52293.2 - 1.1e-13 51.1 1.0 3.6e-09 36.6 0.0 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AAS52293.2 - 1.8e-06 27.8 0.0 1e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 AAS52293.2 - 0.003 17.1 0.1 0.018 14.6 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 AAS52293.2 - 0.0097 15.1 0.0 0.069 12.4 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_22 PF13401.1 AAS52293.2 - 0.14 12.2 3.3 0.12 12.4 0.1 2.5 2 1 0 2 2 2 0 AAA domain RNA_pol_Rpb1_5 PF04998.12 AAS52294.2 - 2.5e-100 335.3 2.0 4.1e-100 334.5 0.2 2.3 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 AAS52294.2 - 4.9e-65 218.5 1.3 3.6e-64 215.6 0.1 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 AAS52294.2 - 1e-39 135.8 1.1 5.6e-38 130.1 0.0 3.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 AAS52294.2 - 3e-24 84.8 0.0 1.7e-23 82.4 0.0 2.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 AAS52294.2 - 2.8e-19 69.5 15.9 1.7e-18 66.9 4.3 3.7 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 Fungal_trans PF04082.13 AAS52295.2 - 9.2e-10 37.8 0.1 2.2e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS52295.2 - 0.00014 21.7 9.1 0.00031 20.5 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1600 PF07667.6 AAS52295.2 - 0.08 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) SHS2_Rpb7-N PF03876.12 AAS52297.1 - 1.1e-12 47.8 0.0 1.8e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pkinase PF00069.20 AAS52299.2 - 9.5e-65 218.3 0.0 1.2e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52299.2 - 8.4e-33 113.5 0.0 1.4e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 AAS52299.2 - 5.6e-20 71.2 0.1 2.1e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 AAS52299.2 - 0.0008 18.4 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AAS52299.2 - 0.0027 16.7 0.0 0.0053 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Vps5 PF09325.5 AAS52300.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Vps5 C terminal like SOG2 PF10428.4 AAS52301.2 - 1.6e-150 501.6 14.0 2.5e-150 501.0 9.7 1.3 1 0 0 1 1 1 1 RAM signalling pathway protein LRR_4 PF12799.2 AAS52301.2 - 1.3e-19 69.3 9.9 1.9e-09 36.9 0.4 4.5 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AAS52301.2 - 2.8e-17 62.2 9.8 1.7e-11 43.7 1.2 3.9 3 1 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 AAS52301.2 - 2.1e-09 36.1 11.3 0.12 12.4 0.0 7.1 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 AAS52301.2 - 1.6e-05 24.2 9.5 0.23 11.7 0.0 5.9 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 AAS52301.2 - 3.2 8.0 12.9 11 6.4 0.0 5.9 8 0 0 8 8 8 0 Leucine Rich repeat Cyto_heme_lyase PF01265.12 AAS52302.1 - 6.2e-69 232.4 0.0 7.1e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase PPR_3 PF13812.1 AAS52303.2 - 0.0089 16.2 0.2 40 4.8 0.0 4.3 4 0 0 4 4 4 1 Pentatricopeptide repeat domain YqeY PF09424.5 AAS52303.2 - 0.086 12.6 0.1 1.1 9.0 0.1 2.8 2 1 1 3 3 3 0 Yqey-like protein Cyclin_N PF00134.18 AAS52304.2 - 5.5e-31 106.7 0.8 8.8e-31 106.1 0.5 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cupin_8 PF13621.1 AAS52305.1 - 2e-44 151.9 0.0 1.9e-42 145.5 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 AAS52305.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase Nucleoplasmin PF03066.10 AAS52305.1 - 0.49 9.8 8.1 1.5 8.3 5.6 1.7 1 0 0 1 1 1 0 Nucleoplasmin ETF_QO PF05187.8 AAS52307.2 - 2.4e-40 136.9 0.0 4e-40 136.2 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 AAS52307.2 - 1e-09 37.8 2.1 0.00033 19.6 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AAS52307.2 - 4.1e-07 29.1 1.0 0.0032 16.3 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 AAS52307.2 - 7e-06 25.9 0.1 2.3e-05 24.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AAS52307.2 - 1.9e-05 23.8 0.1 0.063 12.3 0.1 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.1 AAS52307.2 - 0.00015 21.8 0.1 0.00035 20.7 0.1 1.5 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AAS52307.2 - 0.00022 21.1 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AAS52307.2 - 0.00046 18.7 0.6 0.0019 16.7 0.3 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 AAS52307.2 - 0.00094 18.3 0.5 0.0041 16.2 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Fer4_7 PF12838.2 AAS52307.2 - 0.0024 18.2 0.6 0.0074 16.6 0.4 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox PF00070.22 AAS52307.2 - 0.0033 17.7 0.0 5.5 7.4 0.0 2.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AAS52307.2 - 0.0046 16.7 0.1 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 AAS52307.2 - 0.0061 15.6 0.0 0.0096 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AAS52307.2 - 0.015 14.2 0.2 0.021 13.7 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein RhoGEF PF00621.15 AAS52308.1 - 4.7e-40 137.3 5.1 1.3e-39 135.9 3.5 1.8 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 AAS52308.1 - 8e-36 121.9 0.4 2.9e-35 120.1 0.3 2.0 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.1 AAS52308.1 - 7.3e-23 80.9 2.5 7.8e-22 77.6 1.8 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 AAS52308.1 - 2e-06 27.3 0.4 6.1e-06 25.8 0.3 1.9 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 AAS52308.1 - 0.0046 17.1 0.7 0.014 15.5 0.5 1.9 1 0 0 1 1 1 1 PH domain COPIIcoated_ERV PF07970.7 AAS52309.1 - 7.8e-68 228.4 0.0 9.5e-68 228.1 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 AAS52309.1 - 1.9e-30 104.6 0.0 4.1e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PX PF00787.19 AAS52310.2 - 1.6e-21 76.2 0.1 2e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 PX domain CBFD_NFYB_HMF PF00808.18 AAS52311.1 - 9.6e-23 80.0 2.1 1.3e-22 79.6 1.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AAS52311.1 - 9.1e-17 60.9 0.2 1.2e-16 60.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 AAS52311.1 - 0.00096 18.9 0.2 0.0014 18.4 0.1 1.2 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TAF PF02969.12 AAS52311.1 - 0.07 13.0 0.3 0.12 12.3 0.1 1.5 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) DUF3791 PF12668.2 AAS52311.1 - 0.094 12.3 0.1 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) DUF3453 PF11935.3 AAS52312.1 - 9.9e-61 205.1 0.0 1.8e-60 204.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) SAM_2 PF07647.12 AAS52313.2 - 2.7e-07 30.3 0.0 6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 AAS52313.2 - 7.9e-07 29.1 0.3 1.9e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Erf4 PF10256.4 AAS52313.2 - 0.17 11.7 0.5 0.36 10.7 0.3 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family PDEase_I PF00233.14 AAS52314.2 - 2.8e-42 145.0 0.0 4.8e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GCV_H PF01597.14 AAS52315.2 - 6.6e-40 135.5 0.0 7.7e-40 135.3 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein BolA PF01722.13 AAS52316.1 - 3.4e-24 84.5 1.2 4.3e-24 84.2 0.9 1.1 1 0 0 1 1 1 1 BolA-like protein BolA PF01722.13 AAS52317.1 - 7.7e-16 57.8 0.0 1.4e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 BolA-like protein eIF2A PF08662.6 AAS52318.1 - 2.1e-29 102.6 2.7 4.6e-25 88.4 1.1 4.3 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 AAS52318.1 - 2.4e-09 36.7 0.1 5.8e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS52318.1 - 6.2e-07 29.3 0.1 1.6e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS52318.1 - 1.8e-05 24.4 0.0 8.3e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mto2_bdg PF12808.2 AAS52319.2 - 0.0066 16.5 4.6 0.0066 16.5 3.2 5.9 6 0 0 6 6 6 1 Micro-tubular organiser Mto1 C-term Mto2-binding region BSD PF03909.12 AAS52319.2 - 0.0077 15.9 0.7 0.0077 15.9 0.5 3.1 2 0 0 2 2 2 1 BSD domain DUF904 PF06005.7 AAS52319.2 - 0.016 15.4 5.3 0.016 15.4 3.7 6.8 4 1 2 6 6 6 0 Protein of unknown function (DUF904) Prp19 PF08606.6 AAS52319.2 - 0.057 13.1 0.3 0.057 13.1 0.2 4.2 4 1 1 5 5 5 0 Prp19/Pso4-like Na_K-ATPase PF00287.13 AAS52319.2 - 0.41 9.3 4.0 2.4 6.8 0.0 3.3 3 1 1 4 4 4 0 Sodium / potassium ATPase beta chain Reo_sigmaC PF04582.7 AAS52319.2 - 1.1 8.3 16.0 1 8.4 3.4 3.0 2 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF4407 PF14362.1 AAS52319.2 - 1.9 7.3 28.2 0.18 10.7 0.6 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) AAA_13 PF13166.1 AAS52319.2 - 2.3 6.5 50.9 0.027 12.9 13.0 3.5 2 1 2 4 4 4 0 AAA domain Proteasome PF00227.21 AAS52320.1 - 3.7e-51 173.1 0.0 4.6e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AAS52320.1 - 8.5e-12 44.1 0.9 9.5e-12 44.0 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Miro PF08477.8 AAS52321.1 - 6.8e-41 139.5 0.0 2.9e-20 72.9 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 AAS52321.1 - 2e-29 101.1 0.0 6.5e-29 99.5 0.0 1.9 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.7 AAS52321.1 - 1.4e-28 97.9 0.7 2.6e-28 97.0 0.5 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 AAS52321.1 - 1.8e-23 82.7 0.0 3.6e-11 42.7 0.0 2.7 2 1 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 AAS52321.1 - 2.1e-09 37.3 0.0 0.00032 20.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.27 AAS52321.1 - 1.3e-07 30.3 1.3 0.0046 16.1 0.5 3.2 3 0 0 3 3 3 2 EF hand Dynamin_N PF00350.18 AAS52321.1 - 1e-06 28.6 0.0 0.046 13.5 0.0 2.5 2 0 0 2 2 2 2 Dynamin family EF-hand_7 PF13499.1 AAS52321.1 - 1.8e-06 27.9 0.4 0.048 13.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AAS52321.1 - 1.8e-05 24.2 3.8 0.017 15.0 0.6 3.3 3 0 0 3 3 2 2 EF-hand domain AAA_16 PF13191.1 AAS52321.1 - 5.2e-05 23.3 0.0 0.077 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 AAS52321.1 - 0.0011 19.0 0.0 0.15 12.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 AAS52321.1 - 0.0012 18.5 0.1 0.34 10.6 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 AAS52321.1 - 0.0012 18.4 0.0 0.71 9.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 AAS52321.1 - 0.0021 17.5 0.0 0.38 10.1 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain EF-hand_8 PF13833.1 AAS52321.1 - 0.0022 17.5 1.5 1.1 8.9 0.6 2.7 2 0 0 2 2 2 1 EF-hand domain pair AAA_29 PF13555.1 AAS52321.1 - 0.0026 17.2 0.0 2.6 7.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain EF-hand_5 PF13202.1 AAS52321.1 - 0.0041 16.3 1.5 0.013 14.8 1.0 1.8 1 0 0 1 1 1 1 EF hand ABC_tran PF00005.22 AAS52321.1 - 0.0078 16.5 0.0 2.3 8.5 0.0 2.4 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.22 AAS52321.1 - 0.0088 15.4 0.0 17 4.7 0.0 3.5 4 0 0 4 4 4 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 AAS52321.1 - 0.009 15.2 0.0 0.057 12.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 AAS52321.1 - 0.018 15.2 0.0 3.8 7.7 0.0 2.7 2 1 0 2 2 2 0 RNA helicase Arf PF00025.16 AAS52321.1 - 0.018 14.2 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Arch_ATPase PF01637.13 AAS52321.1 - 0.037 13.7 0.1 8 6.0 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase FeoB_N PF02421.13 AAS52321.1 - 0.048 12.9 0.0 4 6.7 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B Septin PF00735.13 AAS52321.1 - 0.07 12.1 0.0 0.42 9.5 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_32 PF13654.1 AAS52321.1 - 0.12 11.0 0.0 1 7.9 0.0 2.2 3 0 0 3 3 3 0 AAA domain Amidinotransf PF02274.12 AAS52321.1 - 0.18 10.8 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Amidinotransferase Zn_clus PF00172.13 AAS52322.2 - 5.9e-11 42.0 15.2 1.2e-10 41.0 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rsbr_N PF08678.5 AAS52322.2 - 0.025 14.4 5.7 1.9 8.3 0.0 3.9 3 1 1 4 4 4 0 Rsbr N terminal GDPD PF03009.12 AAS52322.2 - 0.046 13.2 0.6 0.23 10.9 0.1 2.2 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Zn_clus PF00172.13 AAS52323.1 - 6.1e-09 35.6 8.9 1.2e-08 34.6 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 AAS52324.1 - 2.4e-09 36.9 10.8 4.6e-09 36.0 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex24p PF06398.6 AAS52324.1 - 0.0067 15.2 2.2 0.016 13.9 1.6 1.6 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DLH PF01738.13 AAS52325.1 - 4.6e-32 111.0 0.4 5.8e-32 110.7 0.3 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AAS52325.1 - 2.4e-08 33.8 0.1 3.1e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AAS52325.1 - 0.00028 20.8 0.6 0.32 10.8 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family TRP PF06011.7 AAS52326.2 - 2.4e-157 524.0 33.0 3.1e-157 523.6 22.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 AAS52326.2 - 4.9e-40 136.8 0.8 7.8e-40 136.1 0.5 1.3 1 0 0 1 1 1 1 ML-like domain DUF4154 PF13689.1 AAS52326.2 - 0.025 14.1 0.1 0.067 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) HemY_N PF07219.8 AAS52326.2 - 1.3 8.6 6.0 15 5.1 0.6 2.9 2 0 0 2 2 2 0 HemY protein N-terminus AMP-binding PF00501.23 AAS52327.1 - 2.6e-91 306.1 0.1 3.2e-91 305.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AAS52327.1 - 1.2e-18 67.8 0.1 2.7e-18 66.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CH PF00307.26 AAS52328.2 - 2.9e-08 33.7 0.0 3.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Peroxin-22 PF12827.2 AAS52329.1 - 4.2e-23 81.2 0.0 5.3e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family DUF3701 PF12482.3 AAS52329.1 - 0.044 13.5 0.1 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Phage integrase protein Rad1 PF02144.11 AAS52330.1 - 9.1e-66 221.4 0.0 1.1e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ribosomal_L7Ae PF01248.21 AAS52331.1 - 2.2e-23 81.5 0.2 2.8e-23 81.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.7 AAS52331.1 - 0.013 15.5 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) GDI PF00996.13 AAS52332.2 - 1.7e-56 191.4 0.0 2.2e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Kelch_4 PF13418.1 AAS52333.1 - 1.9e-11 43.5 4.1 2.4e-05 24.0 0.2 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.1 AAS52333.1 - 3.8e-10 39.5 5.4 0.46 10.4 0.0 6.6 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.1 AAS52333.1 - 4.6e-08 32.9 3.6 0.025 14.7 0.0 5.9 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.1 AAS52333.1 - 1.6e-06 28.0 4.9 0.0047 17.0 0.0 5.8 6 1 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.10 AAS52333.1 - 3.7e-05 23.3 8.7 1.7 8.5 0.0 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 AAS52333.1 - 8.3e-05 22.0 3.0 0.76 9.3 0.0 4.5 4 0 0 4 4 4 2 Kelch motif IlvB_leader PF08049.6 AAS52334.1 - 0.13 11.9 1.2 0.33 10.7 0.9 1.6 1 0 0 1 1 1 0 IlvB leader peptide LRR_4 PF12799.2 AAS52335.1 - 1.6e-17 62.6 31.6 3.7e-05 23.2 0.1 7.9 5 3 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AAS52335.1 - 5e-13 48.5 32.0 0.00028 20.5 1.3 6.1 4 2 2 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 AAS52335.1 - 5.6e-08 31.7 37.3 0.5 10.6 0.0 11.6 8 3 3 11 11 11 2 Leucine Rich Repeat LRR_6 PF13516.1 AAS52335.1 - 1.1e-07 31.1 35.1 0.92 9.7 0.0 10.9 10 2 2 12 12 12 4 Leucine Rich repeat LRR_7 PF13504.1 AAS52335.1 - 5.1e-06 25.8 31.2 14 6.4 0.0 11.5 11 1 1 12 12 12 1 Leucine rich repeat LRR_9 PF14580.1 AAS52335.1 - 0.00017 21.2 4.1 0.0055 16.2 0.1 2.9 2 1 0 3 3 3 2 Leucine-rich repeat Aldedh PF00171.17 AAS52336.2 - 3.2e-179 596.1 0.2 3.6e-179 595.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 AAS52336.2 - 0.058 12.6 0.1 9.2 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Alb1 PF09135.6 AAS52338.1 - 1.8e-28 99.3 17.3 2.6e-28 98.8 12.0 1.2 1 0 0 1 1 1 1 Alb1 V_ATPase_I PF01496.14 AAS52338.1 - 1.6 6.4 4.8 1.6 6.5 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mannosyl_trans3 PF11051.3 AAS52339.1 - 2.2e-61 207.5 0.0 3.1e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Sds3 PF08598.6 AAS52340.2 - 1.5e-47 161.7 0.2 1.5e-47 161.7 0.2 2.4 2 1 0 2 2 2 1 Sds3-like Ribosomal_S19 PF00203.16 AAS52341.1 - 6.2e-33 112.2 0.1 8.9e-33 111.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.14 AAS52342.1 - 1.7e-24 86.0 14.0 2.1e-24 85.6 9.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sugar-bind PF04198.8 AAS52342.1 - 0.02 13.8 0.2 0.027 13.3 0.1 1.1 1 0 0 1 1 1 0 Putative sugar-binding domain DUF2433 PF10360.4 AAS52342.1 - 0.07 13.4 0.0 0.079 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) KfrA_N PF11740.3 AAS52342.1 - 0.64 10.4 7.4 1.1 9.7 5.1 1.4 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Cys_Met_Meta_PP PF01053.15 AAS52343.1 - 4.5e-144 479.4 0.1 5.1e-144 479.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 AAS52343.1 - 7.6e-06 24.4 0.0 1.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.16 AAS52343.1 - 0.00011 21.3 0.0 0.00017 20.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 AAS52343.1 - 0.025 13.3 0.0 0.044 12.5 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-V GDC-P PF02347.11 AAS52343.1 - 0.031 12.9 0.0 0.058 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 AAS52343.1 - 0.035 13.2 0.0 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase DUF775 PF05603.7 AAS52345.1 - 2.8e-58 196.7 0.1 3.2e-58 196.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF3682 PF12446.3 AAS52345.1 - 0.16 12.3 1.6 0.28 11.4 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) tRNA-synt_1c PF00749.16 AAS52346.1 - 2.3e-110 368.1 0.0 2.8e-110 367.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Synthase_beta PF11421.3 AAS52346.1 - 0.04 14.5 0.9 0.11 13.2 0.6 1.8 1 0 0 1 1 1 0 ATP synthase F1 beta subunit SMC_N PF02463.14 AAS52347.2 - 1.3e-21 76.8 17.6 1.3e-20 73.5 12.2 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AAS52347.2 - 5e-19 69.4 7.4 5e-19 69.4 5.1 5.0 2 2 2 4 4 3 1 AAA domain AAA_29 PF13555.1 AAS52347.2 - 8.6e-06 25.1 0.0 1.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 AAS52347.2 - 8.7e-05 22.6 0.1 8.7e-05 22.6 0.1 3.2 3 1 1 4 4 4 1 AAA domain AAA_25 PF13481.1 AAS52347.2 - 0.0007 19.0 0.1 0.0083 15.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 AAS52347.2 - 0.0095 15.6 0.6 0.058 13.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain MutS_V PF00488.16 AAS52347.2 - 0.018 14.4 0.0 0.14 11.5 0.0 2.2 2 0 0 2 2 2 0 MutS domain V ABC_tran PF00005.22 AAS52347.2 - 0.035 14.3 0.0 0.035 14.3 0.0 5.3 3 2 0 4 4 3 0 ABC transporter AAA_33 PF13671.1 AAS52347.2 - 0.073 12.9 3.1 0.61 9.9 0.0 3.9 3 1 1 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.13 AAS52347.2 - 0.18 11.2 0.0 0.18 11.2 0.0 3.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF3035 PF11233.3 AAS52347.2 - 0.19 11.7 2.4 0.66 10.0 1.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) AAA_17 PF13207.1 AAS52347.2 - 6.4 7.6 7.4 14 6.4 2.7 3.6 2 1 0 2 2 2 0 AAA domain DUF3722 PF12519.3 AAS52349.2 - 1.1e-75 254.2 3.4 1.1e-75 254.2 2.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 AAS52349.2 - 0.0088 15.3 0.0 0.063 12.5 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic porin Spo7 PF03907.8 AAS52350.1 - 2.2e-92 308.3 3.5 2.8e-92 308.0 2.4 1.1 1 0 0 1 1 1 1 Spo7-like protein OPT PF03169.10 AAS52350.1 - 0.0022 16.5 0.0 0.0028 16.1 0.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3671 PF12420.3 AAS52350.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function B56 PF01603.15 AAS52351.2 - 1e-147 492.0 15.7 9e-140 465.8 7.2 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) FUN14 PF04930.10 AAS52352.1 - 8.6e-06 25.9 5.9 2.3e-05 24.6 4.1 1.8 1 1 0 1 1 1 1 FUN14 family zf-CCCH PF00642.19 AAS52353.1 - 1.2e-11 44.0 30.9 0.0018 17.9 0.4 5.5 4 2 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.20 AAS52354.2 - 9.2e-19 67.5 0.0 1.2e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52354.2 - 4.5e-08 32.4 0.0 6e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AAS52354.2 - 9.7e-05 22.2 1.6 9.7e-05 22.2 1.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 AAS52354.2 - 0.071 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pil1 PF13805.1 AAS52355.1 - 1.9e-153 509.3 0.2 2.2e-153 509.1 0.2 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 COG4 PF08318.7 AAS52356.1 - 1.9e-119 398.3 0.8 1.9e-119 398.3 0.5 1.6 2 0 0 2 2 2 1 COG4 transport protein DUF3218 PF11508.3 AAS52356.1 - 0.021 14.3 0.0 0.38 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3218) MCPsignal PF00015.16 AAS52356.1 - 0.025 14.1 3.4 0.16 11.4 1.9 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain UvrD-helicase PF00580.16 AAS52356.1 - 0.028 13.7 5.8 0.053 12.8 4.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DASH_Dad3 PF08656.5 AAS52356.1 - 0.058 13.1 4.8 0.33 10.6 0.1 3.1 1 1 1 2 2 2 0 DASH complex subunit Dad3 DUF2450 PF10475.4 AAS52356.1 - 0.18 10.6 8.3 0.45 9.3 5.8 1.6 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) ACDC PF14733.1 AAS52356.1 - 0.42 10.7 5.0 0.43 10.7 0.0 3.7 5 0 0 5 5 5 0 AP2-coincident C-terminal Fork_head PF00250.13 AAS52357.2 - 8e-33 112.3 0.3 1.9e-32 111.1 0.2 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 AAS52357.2 - 2.9e-11 43.3 0.1 6.4e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 FHA domain Proteasome PF00227.21 AAS52358.2 - 8.2e-49 165.4 0.1 9.9e-49 165.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_L5_C PF00673.16 AAS52359.1 - 3.8e-23 81.0 0.0 5.5e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AAS52359.1 - 3e-20 71.7 0.1 8.6e-20 70.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 BCAS2 PF05700.6 AAS52360.1 - 4.6e-09 36.0 10.8 8e-06 25.4 4.3 2.3 2 1 0 2 2 2 2 Breast carcinoma amplified sequence 2 (BCAS2) L51_S25_CI-B8 PF05047.11 AAS52360.1 - 0.038 13.7 0.0 0.63 9.8 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Nanovirus_C8 PF05629.6 AAS52360.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 1 0 1 1 1 0 Nanovirus component 8 (C8) protein FliD_C PF07195.7 AAS52360.1 - 0.12 11.6 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DivIC PF04977.10 AAS52360.1 - 0.48 9.9 5.5 1.4 8.4 3.8 1.7 1 0 0 1 1 1 0 Septum formation initiator IF-2B PF01008.12 AAS52362.1 - 6.5e-100 333.7 0.1 1.1e-99 332.9 0.0 1.4 1 0 0 1 1 1 1 Initiation factor 2 subunit family XPG_I PF00867.13 AAS52362.1 - 0.44 10.6 3.8 4 7.5 0.0 3.0 2 1 1 3 3 3 0 XPG I-region SOBP PF15279.1 AAS52362.1 - 4.8 7.4 10.0 10 6.3 4.7 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein L51_S25_CI-B8 PF05047.11 AAS52363.1 - 3.6e-12 45.8 0.0 6e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF3818 PF12825.2 AAS52364.1 - 1e-123 412.4 12.5 1.7e-123 411.6 8.7 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 AAS52364.1 - 1.2e-46 157.7 0.1 3.5e-46 156.1 0.1 1.9 1 0 0 1 1 1 1 PX-associated PX PF00787.19 AAS52364.1 - 3.2e-07 30.1 0.1 3.6e-06 26.7 0.0 2.8 2 1 0 2 2 2 1 PX domain SLX9 PF15341.1 AAS52365.1 - 7e-21 74.8 4.8 7e-21 74.8 3.4 1.7 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 DUF3486 PF11985.3 AAS52365.1 - 0.025 14.6 2.6 0.027 14.5 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3486) MAS20 PF02064.10 AAS52366.1 - 1.3e-15 57.3 0.4 1.5e-14 53.9 0.3 2.0 1 1 0 1 1 1 1 MAS20 protein import receptor Nucleocapsid-N PF11030.3 AAS52366.1 - 0.0061 16.3 0.1 0.36 10.6 0.1 2.1 1 1 1 2 2 2 2 Nucleocapsid protein N DUF4149 PF13664.1 AAS52367.2 - 2.1e-16 59.8 0.9 2.1e-16 59.8 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) NfeD PF01957.13 AAS52367.2 - 0.099 12.7 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Peptidase_M22 PF00814.20 AAS52368.1 - 4.8e-83 278.7 0.0 5.9e-83 278.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 AAS52368.1 - 0.0063 15.6 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 Carbamoyltransferase DASH_Spc34 PF08657.5 AAS52369.1 - 1.3e-79 267.5 1.7 1.4e-79 267.4 1.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Spc34 Swi5 PF07061.6 AAS52369.1 - 0.05 13.3 0.1 0.13 12.0 0.1 1.8 1 0 0 1 1 1 0 Swi5 DUF904 PF06005.7 AAS52369.1 - 1.1 9.6 5.1 0.46 10.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) HALZ PF02183.13 AAS52369.1 - 2.5 7.8 7.3 2.3 8.0 0.3 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper WD40 PF00400.27 AAS52370.1 - 8.3e-38 126.9 3.3 7.4e-09 35.1 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 AAS52370.1 - 3.9e-07 28.5 7.3 0.012 13.7 0.0 4.3 1 1 1 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 AAS52370.1 - 8.8e-07 28.6 0.3 5.8e-05 22.8 0.0 3.2 2 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 AAS52370.1 - 0.015 14.1 0.1 0.1 11.3 0.0 2.2 1 1 1 2 2 2 0 Nup133 N terminal like Mdv1 PF11542.3 AAS52370.1 - 0.017 15.0 0.1 0.037 13.9 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial division protein 1 DUF1664 PF07889.7 AAS52370.1 - 0.55 10.0 3.3 0.52 10.1 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COX6B PF02297.12 AAS52371.1 - 2.2e-23 82.0 2.8 2.7e-23 81.7 1.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb RINGv PF12906.2 AAS52371.1 - 0.032 14.2 0.1 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 AAS52371.1 - 0.037 14.0 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.1 AAS52371.1 - 0.054 13.3 0.0 0.095 12.5 0.0 1.5 1 1 0 1 1 1 0 Ring finger domain SUN PF03856.8 AAS52372.1 - 1.4e-83 279.9 13.5 1.8e-83 279.6 9.3 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF333 PF03891.10 AAS52372.1 - 0.0056 16.4 0.8 0.69 9.7 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF333) DUF159 PF02586.9 AAS52373.1 - 3.7e-56 189.9 0.1 4.4e-56 189.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Mur_ligase_M PF08245.7 AAS52374.1 - 3.1e-07 30.6 1.3 4.5e-06 26.8 0.9 2.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 AAS52374.1 - 0.0045 16.9 0.0 0.015 15.3 0.0 1.9 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Med11 PF10280.4 AAS52375.2 - 5.4e-21 74.8 0.1 6.1e-21 74.6 0.1 1.0 1 0 0 1 1 1 1 Mediator complex protein DUF4404 PF14357.1 AAS52375.2 - 0.065 13.6 1.9 0.23 11.9 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) IncA PF04156.9 AAS52375.2 - 0.071 12.7 0.6 0.09 12.3 0.4 1.1 1 0 0 1 1 1 0 IncA protein Nup54 PF13874.1 AAS52375.2 - 0.14 11.8 1.4 0.74 9.4 1.0 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4164 PF13747.1 AAS52375.2 - 1.5 9.0 3.9 13 6.0 0.1 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) GCR1_C PF12550.3 AAS52376.1 - 1e-27 95.7 0.9 2.5e-27 94.5 0.6 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Seryl_tRNA_N PF02403.17 AAS52376.1 - 0.067 13.2 0.6 0.2 11.7 0.4 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain UBN2 PF14223.1 AAS52376.1 - 0.19 11.5 1.6 1.7 8.4 0.6 2.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type She2p PF11435.3 AAS52377.1 - 1.3e-93 312.0 10.8 1.7e-93 311.7 7.5 1.1 1 0 0 1 1 1 1 RNA binding protein She2p Myosin_head PF00063.16 AAS52378.2 - 6.5e-223 741.6 3.4 9.2e-223 741.1 2.3 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 AAS52378.2 - 1.3e-48 164.9 0.0 6.6e-48 162.6 0.0 2.0 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 AAS52378.2 - 6.6e-10 38.2 0.0 1.2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AAS52378.2 - 7.4e-08 31.8 0.3 2.1e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 AAS52378.2 - 2.6e-05 23.6 0.0 5.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 AAS52378.2 - 0.004 17.3 0.0 0.014 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AAS52378.2 - 0.017 14.2 0.4 0.061 12.4 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 AAS52378.2 - 0.018 14.7 0.0 0.079 12.7 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain Hpr_kinase_C PF07475.7 AAS52378.2 - 0.019 14.2 0.1 5 6.4 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain SH3_3 PF08239.6 AAS52378.2 - 0.06 13.5 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Bacterial SH3 domain NACHT PF05729.7 AAS52378.2 - 0.06 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 AAS52378.2 - 0.075 13.8 0.0 0.28 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 AAS52378.2 - 0.078 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 AAS52378.2 - 0.089 12.7 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain DUF552 PF04472.7 AAS52378.2 - 0.13 12.1 0.1 0.74 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF552) IQ PF00612.22 AAS52378.2 - 1.2 8.9 14.8 0.45 10.2 3.6 2.7 1 1 1 2 2 2 0 IQ calmodulin-binding motif TPP_enzyme_N PF02776.13 AAS52379.1 - 1.4e-58 197.2 0.3 7.5e-58 194.8 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AAS52379.1 - 6.1e-49 165.5 0.5 2.7e-47 160.1 0.1 2.9 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 AAS52379.1 - 6.5e-36 123.1 2.1 1.3e-35 122.1 0.3 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain His_Phos_1 PF00300.17 AAS52380.1 - 1.5e-17 64.1 0.2 2e-17 63.7 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SHOCT PF09851.4 AAS52381.1 - 0.17 11.4 0.2 0.17 11.4 0.2 1.5 2 0 0 2 2 2 0 Short C-terminal domain Mid2 PF04478.7 AAS52382.1 - 1.1e-61 206.7 0.5 1.1e-61 206.7 0.4 2.7 2 1 1 3 3 3 1 Mid2 like cell wall stress sensor DUF4448 PF14610.1 AAS52382.1 - 0.006 16.0 0.3 0.018 14.5 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) BUD22 PF09073.5 AAS52382.1 - 0.071 12.1 16.7 0.099 11.6 11.6 1.1 1 0 0 1 1 1 0 BUD22 DUF605 PF04652.11 AAS52382.1 - 0.094 12.1 26.0 0.13 11.5 18.0 1.2 1 0 0 1 1 1 0 Vta1 like DUF912 PF06024.7 AAS52382.1 - 0.45 10.5 0.0 0.45 10.5 0.0 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1510 PF07423.6 AAS52382.1 - 0.82 8.9 10.8 0.25 10.7 4.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Menin PF05053.8 AAS52382.1 - 7.9 4.5 15.4 11 4.0 10.7 1.2 1 0 0 1 1 1 0 Menin Macoilin PF09726.4 AAS52382.1 - 8.5 4.5 30.2 13 3.9 21.0 1.3 1 0 0 1 1 1 0 Transmembrane protein Miff PF05644.6 AAS52382.1 - 9.1 5.8 11.7 15 5.1 8.1 1.4 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff E1-E2_ATPase PF00122.15 AAS52383.2 - 1.7e-76 256.2 0.2 3.5e-76 255.2 0.2 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AAS52383.2 - 3.9e-47 160.1 0.7 3.9e-47 160.1 0.5 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AAS52383.2 - 4.5e-31 108.9 0.0 9.9e-31 107.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AAS52383.2 - 1.1e-18 67.0 0.0 2.1e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AAS52383.2 - 1.3e-16 61.3 0.0 3e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AAS52383.2 - 1.9e-13 49.6 0.0 3.9e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AAS52383.2 - 1.3e-05 24.9 1.0 0.00024 20.7 0.6 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3784 PF12650.2 AAS52383.2 - 3.3 7.7 11.7 0.13 12.2 0.3 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) Sua5_yciO_yrdC PF01300.13 AAS52384.1 - 5.7e-50 169.0 0.0 1.2e-49 167.9 0.0 1.5 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.8 AAS52384.1 - 1.2e-31 109.3 0.0 2e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DisA-linker PF10635.4 AAS52384.1 - 0.05 13.1 0.1 0.085 12.3 0.1 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Zn_clus PF00172.13 AAS52386.2 - 0.00032 20.5 12.4 0.0012 18.7 1.6 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF2_N PF00176.18 AAS52387.2 - 1.2e-68 231.1 0.0 1.7e-68 230.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 AAS52387.2 - 9.2e-53 178.9 0.2 8e-52 175.8 0.2 2.1 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 AAS52387.2 - 5.8e-13 48.5 0.0 3.2e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 AAS52387.2 - 8.3e-08 31.3 0.2 2.9e-07 29.6 0.2 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 AAS52387.2 - 2.7e-06 26.9 0.0 2.1e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 AAS52387.2 - 0.043 13.6 0.0 0.15 11.8 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Ran-binding PF05508.6 AAS52388.1 - 5.1e-111 370.4 2.8 6.8e-111 369.9 2.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein Copper-fist PF00649.13 AAS52389.1 - 1.3e-21 75.5 0.6 1.3e-21 75.5 0.4 2.5 1 1 1 2 2 2 1 Copper fist DNA binding domain FTR1 PF03239.9 AAS52390.1 - 1.4e-85 286.9 8.9 1.7e-85 286.7 6.1 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family FtsX PF02687.16 AAS52390.1 - 0.014 15.1 4.4 0.014 15.1 3.1 3.2 2 1 1 3 3 3 0 FtsX-like permease family UPF0016 PF01169.14 AAS52390.1 - 0.098 12.8 5.4 0.4 10.8 0.1 2.9 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 DUF3169 PF11368.3 AAS52390.1 - 5.4 6.1 8.7 0.82 8.8 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) FlgN PF05130.7 AAS52391.2 - 0.0035 17.5 6.0 0.0035 17.5 4.1 2.0 1 1 1 2 2 2 1 FlgN protein NYD-SP28_assoc PF14775.1 AAS52391.2 - 0.034 13.8 0.7 0.23 11.1 0.0 2.5 2 1 0 2 2 2 0 Sperm tail C-terminal domain DUF3571 PF12095.3 AAS52391.2 - 0.051 13.8 0.5 0.13 12.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3571) LON PF02190.11 AAS52391.2 - 0.11 12.1 0.5 0.27 10.8 0.1 1.7 2 0 0 2 2 2 0 ATP-dependent protease La (LON) domain DUF2161 PF09929.4 AAS52391.2 - 0.19 11.6 2.1 2 8.3 0.7 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2161) THOC7 PF05615.8 AAS52391.2 - 0.2 11.8 3.4 2.3 8.4 1.6 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 DivIC PF04977.10 AAS52391.2 - 1.4 8.4 5.2 0.98 8.9 1.4 2.0 2 0 0 2 2 2 0 Septum formation initiator Rad21_Rec8_N PF04825.8 AAS52392.2 - 1.9e-15 56.7 0.0 3.8e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Bromodomain PF00439.20 AAS52393.1 - 1.4e-34 117.8 7.8 9.3e-22 76.7 0.1 2.7 3 0 0 3 3 3 2 Bromodomain LAMTOR PF15454.1 AAS52394.2 - 2.3e-11 43.7 4.4 3.5e-11 43.2 3.0 1.2 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Ribosomal_L50 PF10501.4 AAS52395.1 - 4e-24 84.7 0.0 8e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S Oxysterol_BP PF01237.13 AAS52397.2 - 1.3e-88 296.8 0.0 1.7e-88 296.5 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein eIF2A PF08662.6 AAS52398.2 - 2e-74 249.4 0.0 1.3e-73 246.9 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 AAS52398.2 - 0.00013 21.6 0.2 5.4 7.0 0.0 5.4 5 0 0 5 5 5 1 WD domain, G-beta repeat Pkinase PF00069.20 AAS52400.2 - 1e-54 185.3 0.0 1.3e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52400.2 - 3.4e-33 114.8 0.0 4.6e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS52400.2 - 8.7e-12 44.5 0.0 9.3e-09 34.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 AAS52400.2 - 0.00046 19.9 0.0 0.079 12.6 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AAS52400.2 - 0.084 11.6 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 AAS52400.2 - 0.095 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_Rpc82 PF05645.8 AAS52402.1 - 3.1e-70 236.6 0.1 5.3e-70 235.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 AAS52402.1 - 1.7e-24 85.4 6.3 8e-21 73.6 0.3 3.5 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 AAS52402.1 - 2e-08 33.6 2.8 0.0029 17.0 0.0 2.9 3 0 0 3 3 3 2 TFIIE alpha subunit Rio2_N PF09202.6 AAS52402.1 - 0.017 15.1 0.5 2 8.5 0.0 2.8 2 0 0 2 2 2 0 Rio2, N-terminal RII_binding_1 PF10522.4 AAS52402.1 - 0.13 12.4 1.6 0.67 10.2 0.3 2.9 2 0 0 2 2 2 0 RII binding domain TPR_19 PF14559.1 AAS52403.2 - 3.8e-29 100.8 5.8 3.1e-06 27.4 0.0 9.1 6 3 3 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 AAS52403.2 - 1.3e-27 95.2 25.6 3.7e-10 39.3 0.0 11.4 8 2 0 11 11 11 5 TPR repeat TPR_16 PF13432.1 AAS52403.2 - 2.1e-24 85.5 18.7 5.9e-07 29.9 0.0 9.7 8 3 4 12 12 10 3 Tetratricopeptide repeat TPR_2 PF07719.12 AAS52403.2 - 4.9e-21 72.8 25.9 3.3e-06 26.5 0.0 13.1 16 0 0 16 16 14 4 Tetratricopeptide repeat TPR_14 PF13428.1 AAS52403.2 - 8.4e-21 72.5 15.3 0.00036 20.9 0.0 13.4 10 5 7 17 17 14 5 Tetratricopeptide repeat TPR_1 PF00515.23 AAS52403.2 - 2.6e-19 67.9 17.3 4.6e-06 25.9 0.0 10.6 11 1 0 11 11 11 3 Tetratricopeptide repeat TPR_6 PF13174.1 AAS52403.2 - 2.7e-16 58.8 4.1 0.34 11.4 0.0 9.8 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 AAS52403.2 - 2.1e-15 56.3 17.3 0.00056 19.7 0.1 9.5 6 2 4 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 AAS52403.2 - 4.8e-12 44.7 19.3 0.00014 21.4 0.0 10.5 10 2 1 11 11 11 2 Tetratricopeptide repeat TPR_7 PF13176.1 AAS52403.2 - 1.4e-10 40.1 11.6 0.0037 16.9 0.0 10.4 12 0 0 12 12 10 1 Tetratricopeptide repeat TPR_17 PF13431.1 AAS52403.2 - 4.8e-10 38.8 10.2 0.25 11.6 0.0 11.2 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_9 PF13371.1 AAS52403.2 - 3.2e-07 30.1 8.5 0.15 11.9 0.0 7.1 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_4 PF07721.9 AAS52403.2 - 7.8e-05 22.7 0.0 21 5.8 0.1 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 AAS52403.2 - 9.5e-05 21.5 11.2 0.0095 15.0 0.1 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 AAS52403.2 - 0.00091 19.2 3.0 2.8 8.1 0.0 5.0 4 1 1 5 5 4 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 AAS52403.2 - 0.0018 17.8 0.0 0.18 11.2 0.0 2.7 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) BTAD PF03704.12 AAS52403.2 - 0.029 14.6 2.5 3.3 8.0 0.0 4.1 3 1 0 3 3 3 0 Bacterial transcriptional activator domain EF-hand_6 PF13405.1 AAS52404.1 - 1.2e-06 27.9 0.8 9.5e-06 25.0 0.1 2.6 2 1 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 AAS52404.1 - 1.6e-06 28.1 0.1 5.9e-06 26.3 0.1 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 AAS52404.1 - 3e-06 26.1 0.1 1.5e-05 23.9 0.1 2.3 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 AAS52404.1 - 7.6e-06 25.0 0.7 2.3e-05 23.5 0.5 1.8 1 0 0 1 1 1 1 EF hand CUE PF02845.11 AAS52404.1 - 0.0087 15.5 1.1 2.2 7.8 0.0 2.9 3 0 0 3 3 3 2 CUE domain EF-hand_8 PF13833.1 AAS52404.1 - 0.052 13.1 0.5 0.25 11.0 0.1 2.2 1 1 1 2 2 2 0 EF-hand domain pair PPR_1 PF12854.2 AAS52404.1 - 0.75 9.3 3.3 29 4.2 0.0 3.2 3 0 0 3 3 3 0 PPR repeat RNA_pol_Rpb6 PF01192.17 AAS52405.1 - 3.3e-23 81.1 0.3 4.6e-23 80.7 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.21 AAS52406.2 - 1.3e-26 91.2 60.2 7.3e-05 22.8 2.1 9.6 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS52406.2 - 1.8e-22 77.9 57.5 0.00068 19.7 0.2 9.6 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AAS52406.2 - 5e-13 48.6 56.8 0.0049 17.0 0.7 9.7 10 0 0 10 10 10 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AAS52406.2 - 1.1e-06 28.5 36.9 0.019 15.1 0.0 8.0 8 1 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AAS52406.2 - 2.7e-06 27.3 30.4 0.35 11.1 0.1 7.1 8 0 0 8 8 8 5 Zinc-finger of C2H2 type ATG13 PF10033.4 AAS52407.1 - 3e-65 219.8 0.0 5.3e-65 219.0 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 hDGE_amylase PF14701.1 AAS52408.1 - 2.2e-170 567.1 0.0 3.1e-170 566.6 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 AAS52408.1 - 4.7e-121 403.9 0.0 7.3e-121 403.3 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 AAS52408.1 - 1.6e-68 230.6 0.0 2.4e-68 230.1 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 AAS52408.1 - 2e-21 75.6 0.0 5.7e-21 74.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 AAS52408.1 - 6.9e-07 28.9 0.0 0.0002 20.8 0.0 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Glycos_transf_2 PF00535.21 AAS52409.1 - 3.4e-30 104.9 0.0 4.7e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AAS52409.1 - 1e-09 38.5 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 AAS52409.1 - 1.6e-06 27.4 0.0 2.2e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 SUA5 PF03481.8 AAS52409.1 - 0.11 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding LSM PF01423.17 AAS52410.1 - 4.1e-14 51.8 0.2 4.7e-14 51.6 0.1 1.0 1 0 0 1 1 1 1 LSM domain PIG-U PF06728.8 AAS52411.1 - 3.9e-97 325.5 39.3 5e-97 325.1 27.3 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Sec23_trunk PF04811.10 AAS52412.1 - 1.2e-73 247.5 0.0 1.6e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 AAS52412.1 - 2e-35 120.3 0.0 4.1e-35 119.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 AAS52412.1 - 9.7e-29 99.7 0.1 1.8e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 AAS52412.1 - 4.3e-16 58.1 4.3 7.9e-16 57.3 3.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 AAS52412.1 - 2.9e-11 42.8 0.0 5.7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat MHC_I PF00129.13 AAS52412.1 - 0.17 11.2 0.0 0.49 9.7 0.0 1.7 2 0 0 2 2 2 0 Class I Histocompatibility antigen, domains alpha 1 and 2 ThiF PF00899.16 AAS52413.2 - 2.5e-19 69.4 0.0 4.1e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 ThiF family HDA2-3 PF11496.3 AAS52414.2 - 1.7e-88 296.3 1.5 2.9e-88 295.5 0.0 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Spc7 PF08317.6 AAS52414.2 - 7.9e-05 21.4 17.2 7.9e-05 21.4 11.9 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein WD40 PF00400.27 AAS52415.1 - 1.4e-56 186.4 8.3 8.5e-13 47.6 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 AAS52415.1 - 2.8e-05 23.9 0.0 0.046 13.4 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A FliT PF05400.8 AAS52415.1 - 0.13 12.6 3.8 0.24 11.8 1.3 2.2 2 0 0 2 2 2 0 Flagellar protein FliT MMS1_N PF10433.4 AAS52415.1 - 0.17 9.9 0.0 0.38 8.8 0.0 1.5 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Prenyltrans PF00432.16 AAS52416.1 - 4.7e-58 192.3 10.2 4.4e-13 48.5 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AAS52416.1 - 1.4e-32 112.4 0.0 2.5e-13 50.4 0.0 3.8 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 AAS52416.1 - 2e-07 31.0 0.0 7.9e-05 22.6 0.0 3.0 1 1 3 4 4 4 2 Prenyltransferase-like A2M_comp PF07678.9 AAS52416.1 - 0.014 14.6 0.0 0.21 10.7 0.0 2.5 4 0 0 4 4 4 0 A-macroglobulin complement component DUF1127 PF06568.6 AAS52416.1 - 0.17 11.3 1.9 0.2 11.1 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) DNA_pol_E_B PF04042.11 AAS52417.1 - 6.6e-49 166.0 0.5 9.3e-49 165.5 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B NBP1 PF08537.5 AAS52418.1 - 1.4e-125 418.8 8.0 1.6e-125 418.6 5.5 1.0 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 DMAP_binding PF06464.6 AAS52418.1 - 0.01 16.4 1.9 0.01 16.4 1.3 1.8 2 0 0 2 2 2 0 DMAP1-binding Domain CorA PF01544.13 AAS52418.1 - 0.15 11.1 0.9 0.21 10.5 0.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Sugarporin_N PF11471.3 AAS52418.1 - 0.32 10.6 4.9 0.62 9.7 3.4 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension AAA PF00004.24 AAS52419.1 - 8.6e-44 148.9 0.0 1.6e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 AAS52419.1 - 4.8e-30 103.2 0.0 4.7e-29 100.0 0.1 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 AAS52419.1 - 1.2e-22 79.4 2.2 4e-22 77.8 1.2 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 AAS52419.1 - 1.6e-06 28.3 0.1 0.0069 16.5 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 AAS52419.1 - 4.5e-06 27.4 0.0 1.8e-05 25.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AAS52419.1 - 8.3e-06 25.0 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 AAS52419.1 - 1.3e-05 24.9 0.0 5.9e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AAS52419.1 - 1.4e-05 24.9 0.0 4.3e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AAS52419.1 - 2.3e-05 23.9 0.0 5.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 AAS52419.1 - 2.4e-05 23.8 0.1 0.019 14.3 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 AAS52419.1 - 3.8e-05 23.7 0.1 0.00076 19.5 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 AAS52419.1 - 6.5e-05 21.9 0.0 0.00023 20.1 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 AAS52419.1 - 7.5e-05 21.6 0.0 0.00012 20.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 AAS52419.1 - 0.00015 21.9 0.1 0.0075 16.4 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_2 PF07724.9 AAS52419.1 - 0.00033 20.6 0.0 0.0019 18.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 AAS52419.1 - 0.00051 19.9 0.1 0.0015 18.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 AAS52419.1 - 0.0038 16.3 0.0 2.2 7.3 0.0 2.3 1 1 1 2 2 2 2 KaiC AAA_18 PF13238.1 AAS52419.1 - 0.0062 16.8 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AAS52419.1 - 0.0063 15.6 0.1 0.12 11.4 0.0 2.3 1 1 1 2 2 2 1 Zeta toxin AAA_24 PF13479.1 AAS52419.1 - 0.015 14.9 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AAS52419.1 - 0.018 14.7 0.1 0.46 10.1 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase AAA_19 PF13245.1 AAS52419.1 - 0.019 14.7 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 AAS52419.1 - 0.025 13.7 0.0 0.063 12.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.6 AAS52419.1 - 0.027 14.3 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Torsin PhoH PF02562.11 AAS52419.1 - 0.039 13.1 0.0 0.087 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 AAS52419.1 - 0.051 13.2 0.0 0.61 9.7 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 AAS52419.1 - 0.077 12.4 0.0 0.27 10.6 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 AAS52419.1 - 0.079 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 AAS52419.1 - 0.081 12.9 0.0 0.2 11.7 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 AAS52419.1 - 0.088 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 AAS52419.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain CPT PF07931.7 AAS52419.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_21 PF13304.1 AAS52419.1 - 0.17 11.7 0.3 2.2 8.1 0.0 2.2 1 1 1 2 2 2 0 AAA domain Pyridox_oxidase PF01243.15 AAS52420.2 - 2.1e-16 59.7 0.0 3.7e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.1 AAS52420.2 - 0.00022 21.0 0.0 0.00061 19.5 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AAS52420.2 - 0.0019 18.0 0.0 0.006 16.4 0.0 1.7 1 1 1 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Phage_tail PF04630.7 AAS52420.2 - 0.031 13.3 0.1 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Phage major tail protein PWWP PF00855.12 AAS52421.1 - 4.6e-16 58.7 0.1 9.7e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 PWWP domain DUF1282 PF06930.7 AAS52423.1 - 0.0052 16.4 0.2 0.0061 16.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) NfeD PF01957.13 AAS52423.1 - 0.16 12.1 0.4 0.18 11.9 0.3 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding WD40 PF00400.27 AAS52424.2 - 3.1e-06 26.8 5.8 0.00014 21.6 0.3 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ_3 PF13570.1 AAS52424.2 - 0.0052 17.0 0.5 12 6.3 0.0 3.8 4 0 0 4 4 4 2 PQQ-like domain HNF-1_N PF04814.8 AAS52424.2 - 2.8 7.9 6.4 4.8 7.2 3.4 2.1 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Med10 PF09748.4 AAS52425.2 - 1.1e-46 157.7 0.5 1.5e-46 157.3 0.2 1.3 1 1 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex FliJ PF02050.11 AAS52425.2 - 0.027 14.5 0.3 0.71 9.9 0.0 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Ribosomal_L50 PF10501.4 AAS52425.2 - 0.056 13.4 0.1 0.36 10.8 0.0 2.2 2 1 1 3 3 3 0 Ribosomal subunit 39S TACC PF05010.9 AAS52425.2 - 0.097 12.4 0.1 0.29 10.8 0.1 1.9 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) PBS_linker_poly PF00427.16 AAS52425.2 - 0.1 12.2 1.4 0.23 11.1 0.1 2.2 2 1 0 2 2 2 0 Phycobilisome Linker polypeptide PAPS_reduct PF01507.14 AAS52426.1 - 7.4e-39 133.3 0.0 9e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family AAA PF00004.24 AAS52427.2 - 1.2e-32 112.8 0.0 2.4e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AAS52427.2 - 3e-07 31.3 0.0 7.7e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AAS52427.2 - 9.9e-07 28.9 0.0 2.6e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AAS52427.2 - 1.7e-06 27.6 0.2 4e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 AAS52427.2 - 1.5e-05 25.0 0.4 0.00011 22.2 0.1 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.1 AAS52427.2 - 8.1e-05 22.9 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 AAS52427.2 - 0.00046 19.2 0.0 0.00066 18.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 AAS52427.2 - 0.00062 19.9 0.0 0.0016 18.5 0.0 1.8 1 1 0 1 1 1 1 RNA helicase AAA_5 PF07728.9 AAS52427.2 - 0.00069 19.3 0.5 0.088 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AAS52427.2 - 0.00096 19.0 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AAS52427.2 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 AAS52427.2 - 0.0013 17.5 0.1 0.0019 16.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 AAS52427.2 - 0.0025 17.4 0.0 0.0046 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 AAS52427.2 - 0.003 17.1 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AAS52427.2 - 0.0038 16.6 0.0 0.015 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 AAS52427.2 - 0.004 16.3 0.0 0.0067 15.6 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 AAS52427.2 - 0.0053 17.1 1.7 0.028 14.7 1.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 AAS52427.2 - 0.0089 15.6 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 AAS52427.2 - 0.016 14.9 1.2 0.19 11.4 0.8 2.2 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 AAS52427.2 - 0.016 14.8 0.1 0.031 13.9 0.0 1.6 1 1 0 1 1 1 0 NACHT domain RuvB_N PF05496.7 AAS52427.2 - 0.023 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 AAS52427.2 - 0.027 14.7 0.0 0.073 13.3 0.0 1.8 2 0 0 2 2 1 0 ABC transporter MarR PF01047.17 AAS52427.2 - 0.027 14.1 0.0 0.097 12.3 0.0 2.0 1 0 0 1 1 1 0 MarR family NB-ARC PF00931.17 AAS52427.2 - 0.03 13.1 0.0 0.062 12.1 0.0 1.5 1 1 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 AAS52427.2 - 0.043 13.5 0.1 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 NTPase T2SE PF00437.15 AAS52427.2 - 0.048 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 AAS52427.2 - 0.054 13.0 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 AAS52427.2 - 0.06 12.7 0.3 0.13 11.7 0.2 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_31 PF13614.1 AAS52427.2 - 0.063 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 AAS52427.2 - 0.082 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 KaiC PF06745.8 AAS52427.2 - 0.083 11.9 0.4 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 KaiC MobB PF03205.9 AAS52427.2 - 0.13 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 AAS52427.2 - 0.14 12.1 0.2 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 AAS52427.2 - 0.15 11.5 0.1 0.37 10.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family UPF0016 PF01169.14 AAS52428.1 - 9.4e-42 141.0 21.5 2.8e-23 81.8 3.7 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 MFS_1 PF07690.11 AAS52428.1 - 1.8e-05 23.6 6.4 3.9e-05 22.5 4.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily LysE PF01810.13 AAS52428.1 - 0.21 10.8 15.0 0.049 12.9 3.0 2.4 2 1 0 2 2 2 0 LysE type translocator 5TM-5TMR_LYT PF07694.7 AAS52428.1 - 0.94 8.7 12.9 0.02 14.2 1.0 2.4 2 0 0 2 2 2 0 5TMR of 5TMR-LYT TauE PF01925.14 AAS52428.1 - 3.5 7.0 21.8 0.56 9.6 4.6 3.3 2 2 0 3 3 3 0 Sulfite exporter TauE/SafE TerC PF03741.11 AAS52428.1 - 6.6 6.1 13.7 5.4 6.4 2.7 2.4 2 0 0 2 2 2 0 Integral membrane protein TerC family DUF3535 PF12054.3 AAS52429.2 - 2.4e-150 501.0 2.6 3.9e-149 497.0 0.1 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 AAS52429.2 - 1.2e-79 267.2 0.0 2e-79 266.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 AAS52429.2 - 2.5e-14 52.0 9.7 0.12 12.5 0.0 8.7 8 0 0 8 8 8 5 HEAT repeat Helicase_C PF00271.26 AAS52429.2 - 1.2e-13 50.7 0.0 2.9e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_EZ PF13513.1 AAS52429.2 - 2.2e-05 24.7 17.7 2.9 8.5 0.3 9.2 10 0 0 10 10 10 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 AAS52429.2 - 5.9e-05 23.3 0.3 0.71 10.2 0.0 5.0 6 1 0 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 AAS52429.2 - 5.2 7.8 7.4 16 6.2 0.0 4.8 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Ribosomal_S4 PF00163.14 AAS52430.1 - 3.9e-27 94.4 1.8 5.9e-27 93.9 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 AAS52430.1 - 3e-12 45.7 0.3 1.1e-11 43.9 0.2 1.9 1 0 0 1 1 1 1 S4 domain Ribosomal_L21e PF01157.13 AAS52431.1 - 1.6e-43 146.5 5.1 2.6e-43 145.8 3.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e LRS4 PF10422.4 AAS52431.1 - 0.015 14.6 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Surface_Ag_2 PF01617.12 AAS52431.1 - 0.085 12.0 0.4 0.1 11.7 0.2 1.2 1 0 0 1 1 1 0 Surface antigen Mito_carr PF00153.22 AAS52432.1 - 8.3e-78 256.2 1.3 9.1e-27 92.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Med8 PF10232.4 AAS52433.1 - 2e-39 135.4 3.0 8.9e-39 133.3 2.1 1.8 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 NPV_P10 PF05531.7 AAS52433.1 - 0.029 14.6 0.2 4.6 7.5 0.0 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Mt_ATP-synt_B PF05405.9 AAS52434.2 - 4e-57 192.2 9.4 4.8e-57 191.9 6.5 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CAF1C_H4-bd PF12265.3 AAS52435.1 - 4.3e-17 61.7 1.0 8.8e-17 60.7 0.7 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 AAS52435.1 - 4.5e-16 58.0 12.8 1e-05 25.1 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat PGI PF00342.14 AAS52436.1 - 6.9e-226 750.3 1.7 8e-226 750.1 1.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase SAP30_Sin3_bdg PF13867.1 AAS52436.1 - 0.059 13.2 0.7 6.8 6.6 0.0 3.0 3 0 0 3 3 3 0 Sin3 binding region of histone deacetylase complex subunit SAP30 GPI2 PF06432.6 AAS52438.1 - 1.2e-65 221.6 23.2 4.6e-65 219.7 16.1 1.7 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase SPC25 PF06703.6 AAS52438.1 - 0.073 12.6 1.8 0.19 11.2 1.3 1.7 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) WD40 PF00400.27 AAS52439.1 - 5.1e-64 210.0 18.6 5.2e-13 48.3 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 AAS52439.1 - 7.1e-51 172.0 1.5 1.2e-50 171.2 1.1 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 AAS52439.1 - 1.6e-06 27.6 0.1 3.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 AAS52439.1 - 3.5e-06 25.4 1.3 0.0027 15.9 0.0 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AAS52439.1 - 0.00015 20.6 0.3 0.041 12.6 0.0 3.2 2 1 1 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 AAS52439.1 - 0.044 12.0 0.0 0.57 8.4 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Hira PF07569.6 AAS52439.1 - 0.061 12.5 0.0 4.7 6.3 0.0 2.8 2 1 1 3 3 3 0 TUP1-like enhancer of split GCR1_C PF12550.3 AAS52440.1 - 3.2e-24 84.5 0.9 3.2e-24 84.5 0.6 1.8 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes ACCA PF03255.9 AAS52440.1 - 0.033 13.7 0.3 0.075 12.5 0.2 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2730 PF10805.3 AAS52440.1 - 0.05 13.3 0.4 0.13 12.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) SNARE PF05739.14 AAS52440.1 - 0.84 9.3 3.4 1.6 8.4 0.1 2.6 2 1 1 3 3 3 0 SNARE domain AAA PF00004.24 AAS52441.1 - 2e-39 134.7 0.0 5.9e-39 133.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 AAS52441.1 - 1.3e-07 31.7 0.8 0.00012 22.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 AAS52441.1 - 1.7e-05 24.0 0.0 3.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AAS52441.1 - 2.9e-05 24.1 0.8 0.0013 18.9 0.1 2.8 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 AAS52441.1 - 5.6e-05 22.8 0.0 0.0009 18.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AAS52441.1 - 0.00013 21.8 2.8 0.033 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 AAS52441.1 - 0.00046 19.0 0.0 0.00089 18.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_11 PF13086.1 AAS52441.1 - 0.00055 19.5 4.3 0.044 13.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 AAS52441.1 - 0.0038 16.9 0.1 0.029 14.1 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 AAS52441.1 - 0.0046 16.4 0.0 0.011 15.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 AAS52441.1 - 0.0047 16.8 0.0 0.016 15.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 AAS52441.1 - 0.0051 16.0 0.1 0.011 14.9 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 AAS52441.1 - 0.01 15.8 6.4 0.017 15.1 0.1 3.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 AAS52441.1 - 0.022 15.5 5.7 0.022 15.5 0.0 3.2 2 2 0 2 2 2 0 AAA domain NACHT PF05729.7 AAS52441.1 - 0.066 12.8 0.2 2.9 7.5 0.0 2.5 1 1 1 2 2 2 0 NACHT domain KaiC PF06745.8 AAS52441.1 - 0.068 12.2 0.5 7 5.6 0.1 2.6 1 1 1 2 2 2 0 KaiC AAA_25 PF13481.1 AAS52441.1 - 0.078 12.3 4.6 0.33 10.3 0.0 2.7 2 1 0 3 3 2 0 AAA domain AAA_18 PF13238.1 AAS52441.1 - 0.093 13.0 5.1 0.11 12.8 0.0 3.3 3 1 0 3 3 3 0 AAA domain AAA_23 PF13476.1 AAS52441.1 - 0.29 11.4 11.6 3.7 7.8 4.2 2.8 3 0 0 3 3 3 0 AAA domain Glyco_transf_15 PF01793.11 AAS52442.1 - 5.1e-119 397.0 3.1 6.3e-119 396.8 2.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase HTH_AraC PF00165.18 AAS52442.1 - 0.067 13.0 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family UCH PF00443.24 AAS52443.1 - 4.8e-36 124.2 0.0 3.1e-35 121.5 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AAS52443.1 - 7.1e-07 28.9 0.5 2.2e-06 27.3 0.1 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF2777 PF10949.3 AAS52443.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) SH3_1 PF00018.23 AAS52444.1 - 2.3e-23 81.3 0.0 1.1e-11 43.9 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 AAS52444.1 - 3.1e-14 52.2 0.1 8.8e-10 38.0 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 AAS52444.1 - 1.2e-13 50.7 0.0 2.2e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 AAS52444.1 - 1.2e-10 40.6 0.1 2e-09 36.8 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain PB1 PF00564.19 AAS52444.1 - 6.2e-07 28.9 0.1 2.6e-06 27.0 0.1 2.0 2 0 0 2 2 2 1 PB1 domain SelB-wing_2 PF09106.6 AAS52444.1 - 0.018 14.9 0.0 0.81 9.6 0.0 2.6 2 0 0 2 2 2 0 Elongation factor SelB, winged helix HTS PF04204.11 AAS52444.1 - 0.089 11.5 0.3 0.18 10.5 0.1 1.6 1 1 0 1 1 1 0 Homoserine O-succinyltransferase VPS9 PF02204.13 AAS52446.2 - 2.5e-19 69.1 1.4 4.6e-19 68.3 1.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain polyprenyl_synt PF00348.12 AAS52447.1 - 2.3e-45 154.5 0.0 3e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Syntaxin-18_N PF10496.4 AAS52447.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus DER1 PF04511.10 AAS52448.2 - 5.5e-08 32.5 4.2 7e-08 32.2 2.9 1.2 1 0 0 1 1 1 1 Der1-like family FUSC PF04632.7 AAS52449.2 - 1.1 7.6 7.6 1.4 7.3 5.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1470 PF07336.6 AAS52449.2 - 3.1 8.1 19.8 0.077 13.3 7.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1470) Cpn10 PF00166.16 AAS52450.2 - 7.3e-27 93.1 0.1 8.2e-27 92.9 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit PRP3 PF08572.5 AAS52451.2 - 1.1e-65 221.1 15.8 1.1e-65 221.1 10.9 1.5 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 AAS52451.2 - 2.5e-23 82.1 0.1 6.1e-22 77.6 0.0 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF1115) Arf PF00025.16 AAS52453.2 - 2.6e-27 95.1 0.0 4.5e-25 87.8 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 AAS52453.2 - 3.1e-14 52.6 0.0 5.3e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS52453.2 - 7.7e-09 36.0 0.0 1.2e-07 32.2 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 AAS52453.2 - 2.3e-08 33.9 0.0 7.7e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.15 AAS52453.2 - 2.1e-05 23.4 0.0 0.001 17.8 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 AAS52453.2 - 0.0013 18.2 0.0 0.14 11.5 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AAS52453.2 - 0.0038 16.4 0.0 0.0059 15.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 AAS52453.2 - 0.0063 15.6 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_17 PF13207.1 AAS52453.2 - 0.0063 17.3 0.0 0.014 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 AAS52453.2 - 0.0086 15.3 0.0 0.023 13.9 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AAS52453.2 - 0.061 13.1 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Dynamin family MobB PF03205.9 AAS52453.2 - 0.064 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 AAS52453.2 - 0.11 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter DUF2470 PF10615.4 AAS52454.1 - 1.8e-08 34.4 0.0 2.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pkinase PF00069.20 AAS52455.1 - 3.4e-77 259.1 0.1 4.9e-77 258.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52455.1 - 1e-38 132.9 0.0 1.4e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 AAS52455.1 - 1.1e-14 54.2 2.0 1.9e-14 53.5 0.3 2.1 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 AAS52455.1 - 2.6e-10 39.7 0.0 1.6e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like YukC PF10140.4 AAS52455.1 - 4.3e-05 22.2 0.3 7.1e-05 21.5 0.2 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC RIO1 PF01163.17 AAS52455.1 - 5.6e-05 22.5 0.7 0.00011 21.6 0.5 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 AAS52455.1 - 0.003 16.6 0.1 0.0056 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AAS52455.1 - 0.078 12.6 0.4 0.45 10.2 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family SIR2 PF02146.12 AAS52456.2 - 2.4e-36 125.1 0.0 3.3e-35 121.4 0.0 2.3 1 1 0 1 1 1 1 Sir2 family DUF2256 PF10013.4 AAS52456.2 - 0.045 13.5 0.2 0.099 12.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Rpr2 PF04032.11 AAS52457.1 - 3.1e-12 46.1 0.3 7.4e-12 44.9 0.2 1.6 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_6 PF13912.1 AAS52457.1 - 0.12 12.3 1.7 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 AAS52457.1 - 6.3 7.3 7.1 9.4 6.8 0.0 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Pex24p PF06398.6 AAS52458.2 - 2.7e-86 289.5 0.5 3.3e-86 289.3 0.4 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin WD40 PF00400.27 AAS52459.1 - 2.2e-10 39.9 0.3 0.0014 18.4 0.0 4.2 4 1 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.1 AAS52459.1 - 5e-06 26.6 0.7 2.7 8.3 0.1 4.6 4 0 0 4 4 4 2 PQQ-like domain DUF3553 PF12073.3 AAS52459.1 - 0.035 13.4 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) SET PF00856.23 AAS52460.2 - 4.3e-05 23.8 0.0 0.00052 20.3 0.0 2.2 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 AAS52461.2 - 1.3e-58 194.4 35.3 1.5e-16 59.8 0.2 6.3 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 AAS52461.2 - 3.3e-46 153.0 32.4 1.5e-09 37.0 0.1 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 AAS52461.2 - 8.5e-37 122.1 36.4 5.7e-08 32.0 0.1 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 AAS52461.2 - 7.2e-23 80.3 23.8 4e-10 39.4 3.3 5.7 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 AAS52461.2 - 9.5e-23 80.3 26.1 0.00013 22.4 1.6 6.6 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 AAS52461.2 - 7.2e-19 66.5 21.5 0.00021 21.6 0.2 9.4 5 3 5 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 AAS52461.2 - 1.2e-18 65.4 31.2 2.7e-05 23.6 0.2 8.4 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.1 AAS52461.2 - 1e-15 56.1 23.1 0.00041 19.9 0.0 8.0 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 AAS52461.2 - 9.3e-15 54.7 29.4 0.00091 19.5 1.1 6.9 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 AAS52461.2 - 1.6e-10 40.3 15.3 0.038 14.1 0.0 8.2 8 1 0 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 AAS52461.2 - 4.1e-10 39.6 15.8 0.00031 20.8 0.8 4.6 3 2 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AAS52461.2 - 9.4e-09 35.0 12.5 0.001 18.8 0.1 6.1 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 AAS52461.2 - 4.1e-07 30.0 28.2 0.8 10.3 0.1 8.6 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 AAS52461.2 - 7.1e-05 22.5 11.4 0.44 10.5 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AAS52461.2 - 0.00053 19.8 11.7 0.58 10.0 0.1 5.6 6 0 0 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat DUF3808 PF10300.4 AAS52461.2 - 0.0017 17.0 0.2 0.0017 17.0 0.2 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) RPN7 PF10602.4 AAS52461.2 - 0.021 14.2 19.0 0.18 11.1 0.0 5.5 3 2 3 6 6 6 0 26S proteasome subunit RPN7 SHNi-TPR PF10516.4 AAS52461.2 - 0.036 13.3 12.2 10 5.4 0.0 6.7 7 0 0 7 7 7 0 SHNi-TPR TPR_20 PF14561.1 AAS52461.2 - 0.081 13.0 14.0 0.24 11.5 0.3 5.2 2 2 2 5 5 5 0 Tetratricopeptide repeat MAS20 PF02064.10 AAS52461.2 - 0.54 10.1 3.9 1.3 8.9 0.0 3.4 3 1 1 4 4 4 0 MAS20 protein import receptor FAM101 PF15068.1 AAS52461.2 - 0.65 9.4 3.6 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 FAM101 family NSF PF02071.15 AAS52461.2 - 5.3 8.0 6.7 4e+02 2.4 0.1 5.6 4 0 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat BTAD PF03704.12 AAS52461.2 - 6.7 7.0 14.7 7.3 6.8 0.2 4.9 3 2 1 4 4 4 0 Bacterial transcriptional activator domain AAA_2 PF07724.9 AAS52462.2 - 7.5e-52 175.6 0.1 1.5e-49 168.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 AAS52462.2 - 9.8e-27 92.6 1.3 2.1e-26 91.5 0.0 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 AAS52462.2 - 1.1e-20 74.2 1.0 1.6e-10 41.2 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AAS52462.2 - 3e-16 59.4 0.1 1.4e-11 44.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AAS52462.2 - 1.9e-12 47.5 6.1 0.00047 20.1 0.1 4.6 4 2 2 6 6 5 3 AAA ATPase domain AAA_22 PF13401.1 AAS52462.2 - 5.1e-08 33.1 0.7 0.0088 16.1 0.0 3.7 4 0 0 4 4 3 2 AAA domain Arch_ATPase PF01637.13 AAS52462.2 - 4.6e-07 29.7 9.7 0.0064 16.2 0.0 4.9 3 2 0 4 4 4 2 Archaeal ATPase Sigma54_activat PF00158.21 AAS52462.2 - 5.2e-07 29.2 0.0 3.2e-05 23.4 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 AAS52462.2 - 2.7e-06 26.9 0.0 0.1 12.0 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_17 PF13207.1 AAS52462.2 - 3.6e-06 27.7 1.6 0.042 14.6 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 AAS52462.2 - 3.4e-05 24.1 6.6 0.062 13.6 0.0 3.5 3 1 0 3 3 3 2 AAA domain ABC_tran PF00005.22 AAS52462.2 - 6.9e-05 23.1 0.2 0.12 12.6 0.0 3.0 3 0 0 3 3 2 1 ABC transporter DUF258 PF03193.11 AAS52462.2 - 0.00018 20.7 0.1 0.053 12.7 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 AAS52462.2 - 0.00018 20.6 0.0 0.003 16.6 0.0 2.7 2 1 0 2 2 2 1 Zeta toxin NACHT PF05729.7 AAS52462.2 - 0.00023 20.8 0.0 0.06 13.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain DUF815 PF05673.8 AAS52462.2 - 0.00052 19.0 0.9 0.42 9.4 0.2 3.6 2 2 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 AAS52462.2 - 0.001 19.0 0.0 0.93 9.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 AAS52462.2 - 0.0011 19.1 0.0 2.9 8.1 0.0 3.3 3 0 0 3 3 2 1 RNA helicase AAA_29 PF13555.1 AAS52462.2 - 0.0012 18.3 0.1 0.27 10.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 AAS52462.2 - 0.0012 18.2 0.0 0.33 10.4 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 AAS52462.2 - 0.0013 18.6 0.1 0.58 10.1 0.0 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Mg_chelatase PF01078.16 AAS52462.2 - 0.0022 17.2 0.1 0.58 9.2 0.0 3.2 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI T2SE PF00437.15 AAS52462.2 - 0.0022 16.9 0.3 0.04 12.8 0.1 2.5 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 AAS52462.2 - 0.0024 17.4 0.1 1.2 8.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 AAS52462.2 - 0.0033 17.1 0.0 2.6 7.8 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 AAS52462.2 - 0.0034 17.0 0.0 1.7 8.3 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 AAS52462.2 - 0.0055 16.3 0.0 4 7.0 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Torsin PF06309.6 AAS52462.2 - 0.0071 16.2 0.0 0.036 13.9 0.0 2.0 2 0 0 2 2 2 1 Torsin AAA_24 PF13479.1 AAS52462.2 - 0.012 15.1 0.0 4.4 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 AAS52462.2 - 0.018 14.6 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.17 AAS52462.2 - 0.02 14.3 0.0 5.6 6.3 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_6 PF12774.2 AAS52462.2 - 0.024 14.1 0.0 5.3 6.4 0.0 2.6 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_21 PF13304.1 AAS52462.2 - 0.035 14.0 1.1 14 5.5 0.0 3.8 3 1 0 4 4 3 0 AAA domain AAA_25 PF13481.1 AAS52462.2 - 0.036 13.4 0.6 7.1 5.9 0.1 3.3 4 1 0 4 4 2 0 AAA domain LacI PF00356.16 AAS52462.2 - 0.052 13.1 0.0 6 6.5 0.0 2.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Miro PF08477.8 AAS52462.2 - 0.06 13.8 0.2 1 9.8 0.0 2.9 3 0 0 3 3 3 0 Miro-like protein ResIII PF04851.10 AAS52462.2 - 0.12 12.2 4.4 3.5 7.4 0.0 4.0 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 AAS52462.2 - 0.27 10.6 2.5 3.1 7.1 0.0 3.6 3 1 0 4 4 4 0 AAA-like domain AAA_23 PF13476.1 AAS52462.2 - 1.5 9.1 19.2 7.4 6.8 0.1 3.6 3 2 0 3 3 3 0 AAA domain bZIP_1 PF00170.16 AAS52463.1 - 9.4e-07 28.7 17.3 9.4e-07 28.7 12.0 2.6 2 2 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 AAS52463.1 - 0.011 16.0 8.3 0.039 14.2 5.8 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor HALZ PF02183.13 AAS52463.1 - 0.014 15.0 2.1 0.028 14.1 1.5 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 AAS52463.1 - 0.016 14.8 2.7 0.033 13.8 1.9 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Phage_GP20 PF06810.6 AAS52463.1 - 0.066 12.6 3.6 0.11 11.9 2.5 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 HemX PF04375.9 AAS52463.1 - 0.16 10.5 4.0 0.19 10.2 2.8 1.1 1 0 0 1 1 1 0 HemX bZIP_2 PF07716.10 AAS52463.1 - 0.31 10.8 17.8 1.1 9.1 2.8 2.4 1 1 1 2 2 2 0 Basic region leucine zipper BMFP PF04380.8 AAS52463.1 - 9.9 6.3 10.4 0.3 11.2 2.4 2.0 3 0 0 3 3 3 0 Membrane fusogenic activity Cellulase PF00150.13 AAS52465.1 - 6.9e-13 48.4 1.7 1.5e-12 47.2 0.9 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PalH PF08733.5 AAS52466.1 - 3.4e-91 305.6 10.3 4.2e-91 305.3 7.1 1.1 1 0 0 1 1 1 1 PalH/RIM21 DUF2142 PF09913.4 AAS52466.1 - 0.063 11.9 15.2 0.015 13.9 4.2 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2142) Dna2 PF08696.6 AAS52467.1 - 1.9e-69 233.1 1.0 8.2e-69 231.0 0.3 2.2 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 AAS52467.1 - 3.3e-47 160.4 0.0 1e-46 158.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 AAS52467.1 - 1.5e-38 132.6 0.1 5.2e-19 68.7 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 AAS52467.1 - 1.9e-11 43.8 0.0 7.7e-11 41.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.2 AAS52467.1 - 1.1e-09 38.0 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.1 AAS52467.1 - 5e-09 35.7 0.0 1.9e-08 33.9 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain Viral_helicase1 PF01443.13 AAS52467.1 - 2.8e-06 27.0 0.1 0.18 11.2 0.0 3.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.12 AAS52467.1 - 4.5e-06 26.6 0.1 0.00061 19.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 AAA_16 PF13191.1 AAS52467.1 - 4.4e-05 23.5 0.1 0.0002 21.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Helicase_RecD PF05127.9 AAS52467.1 - 0.00023 20.8 0.0 0.00083 19.0 0.0 2.0 1 0 0 1 1 1 1 Helicase MobB PF03205.9 AAS52467.1 - 0.00045 19.9 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 AAS52467.1 - 0.00055 19.3 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain T2SE PF00437.15 AAS52467.1 - 0.0007 18.5 0.0 0.0016 17.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 AAS52467.1 - 0.002 17.5 0.0 0.0071 15.8 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PhoH PF02562.11 AAS52467.1 - 0.0031 16.7 0.0 0.0059 15.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.1 AAS52467.1 - 0.0073 16.4 0.0 0.027 14.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 AAS52467.1 - 0.0082 15.8 0.1 0.062 13.0 0.0 2.3 2 0 0 2 2 2 1 NTPase PIF1 PF05970.9 AAS52467.1 - 0.021 13.8 0.0 0.044 12.7 0.0 1.4 1 1 0 1 1 1 0 PIF1-like helicase Arch_ATPase PF01637.13 AAS52467.1 - 0.028 14.1 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase UvrD-helicase PF00580.16 AAS52467.1 - 0.029 13.6 0.3 0.12 11.6 0.0 2.1 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain ResIII PF04851.10 AAS52467.1 - 0.033 14.0 0.1 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.9 AAS52467.1 - 0.037 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 AAS52467.1 - 0.038 14.1 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 AAS52467.1 - 0.04 13.3 0.1 0.13 11.7 0.0 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 AAS52467.1 - 0.041 13.5 0.0 0.12 12.0 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 AAS52467.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 AAS52467.1 - 0.064 12.0 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_33 PF13671.1 AAS52467.1 - 0.066 13.0 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 AAS52467.1 - 0.073 12.0 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 AAS52467.1 - 0.084 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PEPCK_ATP PF01293.15 AAS52467.1 - 0.16 10.4 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_14 PF13173.1 AAS52467.1 - 0.16 11.8 1.3 2.6 7.9 0.1 3.3 2 1 0 2 2 2 0 AAA domain RRM_1 PF00076.17 AAS52468.1 - 3e-36 122.8 0.1 7.8e-15 54.2 0.0 5.3 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS52468.1 - 1.5e-24 85.7 0.0 4.2e-10 39.4 0.0 4.4 4 1 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS52468.1 - 6.3e-14 51.5 0.0 4.4e-06 26.4 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSF_DNA-bind PF00447.12 AAS52469.1 - 4e-24 84.7 0.0 7.2e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Glucosamine_iso PF01182.15 AAS52470.1 - 1.7e-52 178.0 0.2 2.2e-52 177.6 0.2 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CPDase PF07823.6 AAS52471.1 - 1.1e-67 227.3 0.0 1.2e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 AAS52471.1 - 0.011 15.4 0.5 0.22 11.2 0.3 2.2 1 1 1 2 2 2 0 2'-5' RNA ligase superfamily TFIIB PF00382.14 AAS52472.1 - 9.7e-56 185.5 1.0 2.4e-27 94.5 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 AAS52472.1 - 1.4e-32 111.8 1.3 1.4e-32 111.8 0.9 2.7 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 AAS52472.1 - 5.3e-12 44.8 2.2 9.4e-12 44.0 1.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 AAS52472.1 - 3.3e-06 26.7 0.4 0.008 15.7 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 AAS52472.1 - 0.0015 17.6 1.0 0.0027 16.8 0.7 1.4 1 0 0 1 1 1 1 zinc-ribbon domain A2L_zn_ribbon PF08792.5 AAS52472.1 - 0.0049 16.2 2.1 0.0089 15.4 1.5 1.4 1 0 0 1 1 1 1 A2L zinc ribbon domain DZR PF12773.2 AAS52472.1 - 0.12 12.1 0.4 0.25 11.1 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 AAS52472.1 - 0.12 12.3 0.8 0.32 10.9 0.6 1.7 1 0 0 1 1 1 0 Zinc ribbon domain DUF3947 PF13135.1 AAS52472.1 - 0.17 12.0 0.0 0.5 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) SDA1 PF05285.7 AAS52473.1 - 7.9e-88 294.8 28.0 1.7e-46 158.9 7.7 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.7 AAS52473.1 - 1.1e-22 80.0 0.1 2.4e-22 78.9 0.1 1.6 1 0 0 1 1 1 1 NUC130/3NT domain ATP-grasp_2 PF08442.5 AAS52474.1 - 2.6e-73 245.7 0.8 4.2e-73 245.0 0.6 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 AAS52474.1 - 2.9e-25 88.6 0.1 2.9e-25 88.6 0.1 2.5 3 1 0 3 3 3 1 CoA-ligase ATP-grasp_5 PF13549.1 AAS52474.1 - 2.8e-09 36.5 0.6 4.9e-09 35.7 0.4 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 AAS52474.1 - 0.0028 17.2 0.0 0.0088 15.6 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.12 AAS52474.1 - 0.0081 15.4 0.1 0.02 14.2 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 AAS52474.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain MPC PF03650.8 AAS52475.1 - 7e-48 161.5 0.1 8.1e-48 161.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) ANTH PF07651.11 AAS52476.1 - 1.6e-59 200.8 0.3 1.6e-59 200.8 0.2 1.9 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 AAS52476.1 - 2.1e-05 24.3 2.6 4.3e-05 23.3 0.0 2.6 2 1 0 2 2 2 1 ENTH domain AAA_23 PF13476.1 AAS52476.1 - 6.7 6.9 13.4 1.5 9.1 5.1 2.1 2 0 0 2 2 2 0 AAA domain Med15 PF09606.5 AAS52476.1 - 7.3 4.6 51.2 11 4.0 35.5 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PFK PF00365.15 AAS52477.1 - 4.7e-171 567.1 4.2 5.3e-126 419.3 1.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase PAP_assoc PF03828.14 AAS52478.1 - 3.7e-15 55.6 0.0 1e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 AAS52478.1 - 1e-14 54.5 0.0 3.1e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 AAS52478.1 - 0.079 13.0 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase beta palm RF-1 PF00472.15 AAS52479.1 - 7.3e-17 61.2 0.3 1.1e-16 60.6 0.2 1.2 1 0 0 1 1 1 1 RF-1 domain Pkinase PF00069.20 AAS52480.1 - 1.5e-66 224.2 0.6 2.4e-66 223.5 0.1 1.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52480.1 - 1e-50 172.2 0.0 1.4e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 AAS52480.1 - 5.5e-21 74.7 0.4 1.6e-20 73.2 0.2 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 AAS52480.1 - 1.1e-10 41.5 0.0 1.9e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 AAS52480.1 - 2.9e-07 29.7 0.0 5.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 AAS52480.1 - 0.0026 17.9 0.0 0.0095 16.1 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 AAS52480.1 - 0.0046 16.7 0.2 0.026 14.2 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family MSP1_C PF07462.6 AAS52480.1 - 0.041 12.2 0.3 0.065 11.6 0.2 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Kdo PF06293.9 AAS52480.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec7_N PF12783.2 AAS52481.1 - 4.8e-38 130.2 18.2 5e-37 126.9 7.9 4.7 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal PalH PF08733.5 AAS52483.1 - 8.3e-78 261.6 1.2 9.8e-78 261.4 0.8 1.1 1 0 0 1 1 1 1 PalH/RIM21 RabGAP-TBC PF00566.13 AAS52484.1 - 2.7e-44 151.1 0.1 4.2e-44 150.5 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ubiquitin PF00240.18 AAS52485.1 - 9.7e-07 28.1 0.0 1.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 AAS52485.1 - 0.0029 17.7 0.0 0.0032 17.6 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 AAS52485.1 - 0.058 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Erf4 PF10256.4 AAS52486.2 - 1.9e-34 118.0 0.0 2.4e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TruB_N PF01509.13 AAS52487.1 - 9e-40 136.2 0.1 4.4e-38 130.7 0.0 2.3 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) Mid1 PF12929.2 AAS52488.2 - 7.2e-134 446.7 6.7 9.5e-134 446.3 4.6 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 AAS52488.2 - 0.0017 18.6 4.9 0.024 14.9 0.2 2.7 3 0 0 3 3 3 2 Fz domain AAA PF00004.24 AAS52489.1 - 8e-18 64.9 0.0 1.3e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 AAS52489.1 - 1.2e-17 64.0 0.0 1.7e-15 57.0 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 AAS52489.1 - 1e-15 57.4 0.0 2.1e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 AAS52489.1 - 5.3e-08 32.0 0.0 2.1e-06 26.7 0.0 2.1 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AAS52489.1 - 1.7e-07 31.4 0.6 0.014 15.4 0.1 2.5 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 AAS52489.1 - 6.4e-07 28.6 0.0 1.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AAS52489.1 - 2.3e-06 27.7 0.2 1.2e-05 25.4 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain DNA_pol3_delta PF06144.8 AAS52489.1 - 4e-06 26.4 0.0 6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 AAS52489.1 - 5.6e-06 26.2 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AAS52489.1 - 1.6e-05 24.5 0.1 0.00018 21.1 0.0 2.7 3 0 0 3 3 3 1 Part of AAA domain DUF815 PF05673.8 AAS52489.1 - 3.9e-05 22.6 0.0 6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 AAS52489.1 - 5.2e-05 22.7 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.1 AAS52489.1 - 5.4e-05 22.8 0.1 0.00017 21.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AAS52489.1 - 0.00012 22.8 0.1 0.0013 19.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 AAS52489.1 - 0.00025 20.7 0.1 0.0014 18.3 0.0 2.2 2 1 1 3 3 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 AAS52489.1 - 0.00037 20.1 0.6 0.082 12.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 AAS52489.1 - 0.00052 19.5 0.2 0.21 10.9 0.0 2.5 1 1 2 3 3 3 1 AAA-like domain AAA_25 PF13481.1 AAS52489.1 - 0.00053 19.4 0.8 0.016 14.6 0.0 2.7 2 1 1 3 3 3 1 AAA domain ResIII PF04851.10 AAS52489.1 - 0.00073 19.4 0.0 0.021 14.6 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_33 PF13671.1 AAS52489.1 - 0.00079 19.3 0.1 0.0022 17.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 AAS52489.1 - 0.00083 18.9 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 AAS52489.1 - 0.001 18.5 0.1 0.011 15.2 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_18 PF13238.1 AAS52489.1 - 0.0025 18.1 0.0 0.0046 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 AAS52489.1 - 0.0027 16.4 0.0 0.038 12.7 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_24 PF13479.1 AAS52489.1 - 0.0031 17.1 0.0 0.0077 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 AAS52489.1 - 0.007 16.0 0.0 0.044 13.4 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 AAS52489.1 - 0.0078 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase Mg_chelatase PF01078.16 AAS52489.1 - 0.014 14.5 0.0 0.075 12.1 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 AAS52489.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.5 1 1 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.13 AAS52489.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NYD-SP12_N PF15015.1 AAS52489.1 - 0.037 12.2 0.4 0.45 8.6 0.1 2.0 1 1 1 2 2 2 0 Spermatogenesis-associated, N-terminal AAA_28 PF13521.1 AAS52489.1 - 0.038 13.9 0.0 0.1 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 AAS52489.1 - 0.042 12.8 0.0 0.13 11.1 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.17 AAS52489.1 - 0.045 13.2 0.0 0.097 12.1 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain PIF1 PF05970.9 AAS52489.1 - 0.076 11.9 0.0 2.7 6.8 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase AAA_23 PF13476.1 AAS52489.1 - 0.16 12.3 0.8 0.46 10.7 0.5 1.7 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 AAS52489.1 - 0.17 11.7 0.0 1.8 8.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain Cyclin_N PF00134.18 AAS52490.1 - 3.3e-17 62.2 0.0 4e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 AAS52490.1 - 7.6e-11 42.6 0.0 1.1e-10 42.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin DUF3446 PF11928.3 AAS52490.1 - 0.68 10.1 3.9 1.3 9.2 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Rcd1 PF04078.8 AAS52491.1 - 1.6e-123 410.6 3.8 1.9e-123 410.4 2.7 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Adaptin_N PF01602.15 AAS52492.1 - 3.4e-106 355.6 11.7 4.5e-106 355.2 8.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 AAS52492.1 - 1.2e-47 161.5 0.5 3.7e-47 159.9 0.0 2.1 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 AAS52492.1 - 1e-11 44.9 0.1 0.0062 16.7 0.0 5.4 3 1 3 6 6 6 3 HEAT repeats HEAT PF02985.17 AAS52492.1 - 1.5e-07 30.9 0.8 2 8.6 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 AAS52492.1 - 0.033 14.7 2.3 12 6.5 0.0 4.3 4 2 0 4 4 4 0 HEAT-like repeat YchF-GTPase_C PF06071.8 AAS52493.1 - 7.8e-37 124.9 0.1 1.8e-36 123.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 AAS52493.1 - 7.2e-13 48.5 0.0 1.8e-12 47.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AAS52493.1 - 0.0084 15.3 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B SecA_PP_bind PF01043.15 AAS52493.1 - 0.019 15.2 0.5 0.42 10.9 0.0 2.3 2 0 0 2 2 2 0 SecA preprotein cross-linking domain TGS PF02824.16 AAS52493.1 - 0.026 14.3 0.0 0.07 12.9 0.0 1.7 1 0 0 1 1 1 0 TGS domain Dna2 PF08696.6 AAS52493.1 - 0.029 13.6 0.1 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 DNA replication factor Dna2 DUF3236 PF11576.3 AAS52493.1 - 0.089 12.1 1.1 0.21 10.9 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) AAA_23 PF13476.1 AAS52493.1 - 2.6 8.3 6.3 22 5.2 4.2 2.2 1 1 0 1 1 1 0 AAA domain SCO1-SenC PF02630.9 AAS52494.2 - 1.6e-67 226.4 0.0 2e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 AAS52494.2 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family B12-binding PF02310.14 AAS52494.2 - 0.05 13.4 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain DUF2648 PF10855.3 AAS52494.2 - 0.071 12.5 0.5 0.16 11.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) Chitin_synth_1 PF01644.12 AAS52495.1 - 5.7e-77 257.0 1.2 8.5e-77 256.5 0.8 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 AAS52495.1 - 5.6e-25 87.7 2.3 2.3e-18 65.8 0.0 3.1 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.6 AAS52495.1 - 4.9e-24 83.8 0.1 9.8e-24 82.8 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.1 AAS52495.1 - 2.6e-09 37.2 0.0 2.6e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 AAS52495.1 - 2.7e-09 37.0 0.7 2.7e-09 37.0 0.5 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DUF2576 PF10845.3 AAS52495.1 - 0.27 10.4 0.9 0.59 9.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Chitin_synth_2 PF03142.10 AAS52496.2 - 3.3e-283 939.8 0.1 4.7e-283 939.3 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 AAS52496.2 - 1.8e-17 63.7 0.2 6.7e-17 61.8 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AAS52496.2 - 7.8e-14 52.0 0.0 1.6e-12 47.7 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 AAS52496.2 - 9.4e-07 28.5 0.1 5.2e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 AAS52496.2 - 2.5e-05 24.0 0.0 0.0011 18.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 AAS52496.2 - 5.1e-05 22.6 0.0 0.00049 19.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 SHMT PF00464.14 AAS52497.1 - 5.3e-201 667.1 0.0 6.1e-201 666.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Ras PF00071.17 AAS52498.1 - 8.8e-42 142.2 0.2 4.3e-41 140.0 0.1 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 AAS52498.1 - 2e-18 67.0 0.0 2.7e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS52498.1 - 3.2e-17 62.3 0.2 7.5e-17 61.1 0.1 1.5 2 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 AAS52498.1 - 1.3e-07 31.5 0.0 2.3e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AAS52498.1 - 1.4e-05 24.6 0.0 0.00035 20.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AAS52498.1 - 2.7e-05 23.4 0.0 3.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 AAS52498.1 - 0.0044 16.2 0.0 0.0064 15.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 AAS52498.1 - 0.025 13.7 0.0 0.11 11.6 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function, DUF258 G-alpha PF00503.15 AAS52498.1 - 0.094 11.3 0.5 1.8 7.1 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Rif1_N PF12231.3 AAS52499.1 - 3.7e-31 108.4 11.7 6.9e-31 107.5 8.1 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Pkinase PF00069.20 AAS52500.1 - 4.2e-56 189.9 0.0 5.3e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52500.1 - 8.1e-30 103.7 0.0 1.1e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS52500.1 - 1.6e-05 24.0 0.0 2.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AAS52500.1 - 0.0066 16.2 3.9 0.75 9.4 0.0 3.3 1 1 2 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 AAS52500.1 - 0.025 13.9 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 AAS52500.1 - 0.045 12.5 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 UBX PF00789.15 AAS52501.1 - 2e-14 53.4 0.0 2.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 UBX domain Snf7 PF03357.16 AAS52502.2 - 2.6e-14 52.9 3.2 3.3e-14 52.6 2.2 1.1 1 0 0 1 1 1 1 Snf7 Phasin_2 PF09361.5 AAS52502.2 - 0.026 14.5 0.2 0.073 13.1 0.2 1.7 1 0 0 1 1 1 0 Phasin protein Baculo_PEP_C PF04513.7 AAS52502.2 - 0.18 11.6 3.8 0.84 9.4 0.8 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MutS_III PF05192.13 AAS52502.2 - 0.62 9.7 4.0 1.7 8.4 2.6 1.8 1 1 0 1 1 1 0 MutS domain III rRNA_proc-arch PF13234.1 AAS52504.2 - 9.7e-94 313.4 1.5 9.7e-94 313.4 1.1 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 AAS52504.2 - 8e-62 207.6 0.4 2.3e-61 206.1 0.3 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 AAS52504.2 - 1.2e-21 76.9 0.0 1.4e-20 73.4 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS52504.2 - 2.9e-06 27.0 0.0 7.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 AAS52504.2 - 0.053 12.4 0.0 0.13 11.1 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Pkinase PF00069.20 AAS52506.1 - 1.2e-39 136.0 0.0 1.5e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52506.1 - 4e-17 62.1 0.0 5e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 AAS52506.1 - 5.1e-06 25.9 0.0 7.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 AAS52506.1 - 0.00019 20.5 0.0 0.00031 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AAS52506.1 - 0.00041 20.1 1.0 0.0015 18.2 0.7 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AAS52506.1 - 0.014 14.5 0.1 0.031 13.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Vps26 PF03643.10 AAS52507.1 - 1.7e-112 374.7 0.2 1.9e-112 374.5 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 AAS52507.1 - 0.015 15.1 0.7 0.2 11.4 0.2 2.6 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain DUF4497 PF14924.1 AAS52507.1 - 0.069 13.4 0.0 0.57 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) COX3 PF00510.13 AAS52507.1 - 0.091 12.1 0.0 0.18 11.2 0.0 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase subunit III Tim54 PF11711.3 AAS52508.2 - 8e-141 469.0 0.1 9.3e-141 468.8 0.0 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Myb_DNA-binding PF00249.26 AAS52509.1 - 1.6e-22 79.2 1.6 2.2e-12 46.8 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AAS52509.1 - 3.6e-20 71.8 3.6 8.1e-15 54.6 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 AAS52509.1 - 0.019 14.8 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Lysine_decarbox PF03641.9 AAS52510.1 - 1e-44 151.5 0.0 1.3e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase zf-H2C2_2 PF13465.1 AAS52511.2 - 2.8e-22 77.8 55.2 3.4e-08 33.3 0.2 7.1 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2 PF00096.21 AAS52511.2 - 4.7e-17 61.2 77.7 1.5e-05 25.0 0.7 10.0 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS52511.2 - 9.2e-12 44.4 63.8 0.0015 18.6 1.4 10.0 8 1 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AAS52511.2 - 8e-07 29.0 8.7 0.00068 19.6 1.4 7.2 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding Elf1 PF05129.8 AAS52511.2 - 0.011 15.4 1.2 0.011 15.4 0.8 4.0 4 1 1 5 5 5 0 Transcription elongation factor Elf1 like zf-C2H2_6 PF13912.1 AAS52511.2 - 0.042 13.7 0.2 0.028 14.3 2.1 6.8 9 0 0 9 9 9 0 C2H2-type zinc finger zf-met PF12874.2 AAS52511.2 - 0.071 13.3 0.2 0.071 13.3 0.1 7.1 7 0 0 7 7 7 0 Zinc-finger of C2H2 type DUF2225 PF09986.4 AAS52511.2 - 2.1 7.7 9.5 1.8 7.9 0.8 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-BED PF02892.10 AAS52511.2 - 3.7 7.3 31.8 3.2 7.5 2.7 5.9 2 1 3 5 5 5 0 BED zinc finger Pkinase PF00069.20 AAS52512.1 - 3.5e-32 111.5 0.0 7.6e-32 110.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52512.1 - 1.3e-18 67.0 0.0 1.3e-17 63.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DinB PF05163.7 AAS52512.1 - 0.058 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 DinB family DinB_2 PF12867.2 AAS52512.1 - 0.068 13.5 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 DinB superfamily HbrB PF08539.6 AAS52513.1 - 6.7e-41 139.7 0.2 1.1e-40 139.0 0.1 1.4 1 0 0 1 1 1 1 HbrB-like CLN3 PF02487.12 AAS52514.1 - 8.1e-130 433.2 17.6 8.6e-129 429.8 12.2 1.9 1 1 0 1 1 1 1 CLN3 protein Aminotran_1_2 PF00155.16 AAS52515.1 - 3.5e-75 253.2 0.0 4.2e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 AAS52515.1 - 0.00012 21.2 0.0 0.0002 20.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 AAS52515.1 - 0.0094 14.7 0.0 0.12 11.0 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AAS52515.1 - 0.026 12.8 0.0 0.061 11.5 0.0 1.6 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Peptidase_S58 PF03576.9 AAS52515.1 - 0.11 11.6 0.7 0.19 10.8 0.5 1.3 1 0 0 1 1 1 0 Peptidase family S58 DUF1674 PF07896.7 AAS52516.1 - 2.4e-17 62.8 2.6 5.6e-17 61.6 1.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) EF1G PF00647.14 AAS52516.1 - 0.11 12.1 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain Nup88 PF10168.4 AAS52517.2 - 0.00012 20.0 0.0 0.00012 20.0 0.0 1.7 2 0 0 2 2 2 1 Nuclear pore component AMPKBI PF04739.10 AAS52517.2 - 0.1 12.4 0.6 0.24 11.3 0.4 1.5 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain Nup54 PF13874.1 AAS52517.2 - 0.17 11.5 5.1 0.55 9.8 3.5 1.9 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Ribosomal_L37 PF08561.5 AAS52518.1 - 1.6e-28 98.1 0.5 1.8e-28 97.8 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Phosphodiest PF01663.17 AAS52519.2 - 1.1e-16 61.1 1.1 1.3e-15 57.5 0.8 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 AAS52519.2 - 2.6e-05 23.7 0.3 5.1e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 AAS52519.2 - 0.011 14.9 0.0 0.033 13.3 0.0 1.8 2 0 0 2 2 2 0 Sulfatase zf-C2H2_2 PF12756.2 AAS52520.1 - 1.7e-36 124.3 6.3 6.8e-34 116.0 1.2 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) PP_kinase_C PF13090.1 AAS52520.1 - 0.0066 15.0 0.3 0.011 14.3 0.2 1.3 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain zf-C2H2_jaz PF12171.3 AAS52520.1 - 0.02 15.0 0.7 0.079 13.1 0.5 2.1 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding adh_short PF00106.20 AAS52521.1 - 4.7e-24 85.1 6.1 6.2e-24 84.7 4.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AAS52521.1 - 5.4e-16 58.7 3.4 7.4e-16 58.3 2.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AAS52521.1 - 1.1e-05 25.0 0.3 3.1e-05 23.5 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AAS52521.1 - 0.00022 21.3 0.5 0.67 9.9 0.1 2.2 2 0 0 2 2 2 2 NADH(P)-binding Polysacc_synt_2 PF02719.10 AAS52521.1 - 0.00086 18.2 0.0 0.0021 16.9 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 AAS52521.1 - 0.0045 16.7 0.0 0.0058 16.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ribosomal_L17 PF01196.14 AAS52523.1 - 1.2e-24 86.6 0.0 1.8e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Plasmid_stabil PF05016.9 AAS52523.1 - 0.046 14.1 2.6 0.62 10.4 0.2 2.9 3 0 0 3 3 3 0 Plasmid stabilisation system protein PALP PF00291.20 AAS52524.1 - 1.8e-59 201.5 0.0 2.1e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DSPc PF00782.15 AAS52525.1 - 1.1e-21 76.8 0.2 2.4e-19 69.2 0.1 3.2 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AAS52525.1 - 1.2e-05 24.8 0.3 2.5e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 AAS52525.1 - 0.058 13.4 0.2 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate CBFD_NFYB_HMF PF00808.18 AAS52526.1 - 0.00012 22.0 0.2 0.00023 21.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AAS52526.1 - 0.0092 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Paf1 PF03985.8 AAS52528.2 - 3.2e-156 520.4 13.7 3.9e-156 520.1 9.5 1.0 1 0 0 1 1 1 1 Paf1 Esterase PF00756.15 AAS52529.1 - 1.1e-60 205.1 0.0 1.3e-60 204.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 AAS52529.1 - 0.00041 20.1 0.0 0.00063 19.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family RCC1_2 PF13540.1 AAS52530.1 - 2.5e-17 61.9 7.1 1.9e-08 33.7 0.1 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 AAS52530.1 - 3.9e-17 62.1 0.6 5e-05 23.4 0.0 5.8 4 2 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 AAS52530.1 - 0.00023 20.8 0.0 0.00049 19.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like Peptidase_M20 PF01546.23 AAS52531.1 - 3.5e-22 78.8 0.0 6.3e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AAS52531.1 - 2.3e-09 36.9 0.0 4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.27 AAS52531.1 - 1.4e-05 24.7 13.3 0.089 12.7 0.0 6.3 6 1 0 6 6 6 3 WD domain, G-beta repeat DUF4221 PF13970.1 AAS52531.1 - 0.028 13.7 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) WD40 PF00400.27 AAS52532.1 - 4.3e-15 54.9 0.3 0.00019 21.2 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 AAS52532.1 - 0.0093 15.4 0.0 0.24 10.9 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S11 PF00411.14 AAS52533.1 - 3.9e-41 139.6 0.9 4.7e-41 139.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF814 PF05670.8 AAS52533.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF814) Ribosomal_S8 PF00410.14 AAS52534.1 - 2.4e-26 92.0 0.1 3.2e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L39 PF00832.15 AAS52535.1 - 1.7e-22 78.5 10.7 2e-22 78.3 7.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Pkinase PF00069.20 AAS52536.1 - 5e-46 156.9 0.0 7.5e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52536.1 - 2.1e-29 102.3 0.0 3.2e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AAS52536.1 - 0.03 14.0 0.0 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 AAS52536.1 - 0.038 12.9 0.0 0.39 9.6 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Mannosyl_trans3 PF11051.3 AAS52537.2 - 2e-78 263.4 0.0 2.7e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 AAS52537.2 - 0.0048 16.2 0.1 0.014 14.7 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 B12-binding PF02310.14 AAS52537.2 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain muHD PF10291.4 AAS52538.1 - 1.5e-68 230.7 0.0 2.3e-68 230.1 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain SSB PF00436.20 AAS52540.2 - 2.7e-20 72.1 0.0 3.2e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Gon7 PF08738.5 AAS52541.1 - 4.2e-34 116.6 0.1 5e-34 116.3 0.1 1.0 1 0 0 1 1 1 1 Gon7 family MFS_1 PF07690.11 AAS52542.2 - 7.9e-25 87.3 27.2 1.2e-24 86.7 18.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_transf_34 PF05637.7 AAS52543.1 - 8.6e-52 176.0 0.0 1.3e-51 175.4 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_transf_10 PF00852.14 AAS52543.1 - 0.12 10.9 0.1 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) ATP12 PF07542.6 AAS52545.1 - 2.6e-32 111.3 0.0 4.3e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Prefoldin_2 PF01920.15 AAS52546.1 - 1.9e-20 72.6 4.2 2.1e-20 72.4 2.9 1.0 1 0 0 1 1 1 1 Prefoldin subunit Sipho_Gp157 PF05565.6 AAS52546.1 - 0.0042 16.6 2.8 0.062 12.8 0.8 2.0 2 0 0 2 2 2 1 Siphovirus Gp157 YlqD PF11068.3 AAS52546.1 - 0.019 15.0 5.0 0.41 10.6 0.8 2.0 2 0 0 2 2 2 0 YlqD protein HR1 PF02185.11 AAS52546.1 - 0.022 14.5 0.6 0.022 14.5 0.4 2.0 2 1 0 2 2 2 0 Hr1 repeat Tropomyosin_1 PF12718.2 AAS52546.1 - 0.022 14.6 2.2 0.022 14.6 1.5 1.8 2 0 0 2 2 2 0 Tropomyosin like GCM PF03615.10 AAS52546.1 - 0.03 13.9 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 GCM motif protein RRF_GI PF12614.3 AAS52546.1 - 0.04 13.7 0.8 5.1 6.9 0.0 2.0 2 0 0 2 2 2 0 Ribosome recycling factor SlyX PF04102.7 AAS52546.1 - 0.11 12.8 2.7 3.1 8.2 0.2 2.4 2 0 0 2 2 2 0 SlyX RasGAP_C PF03836.10 AAS52546.1 - 0.2 11.3 5.5 2.3 7.8 1.2 2.1 2 0 0 2 2 2 0 RasGAP C-terminus Caudo_TAP PF02413.12 AAS52546.1 - 0.24 11.5 4.8 0.17 12.0 0.6 1.9 1 1 1 2 2 2 0 Caudovirales tail fibre assembly protein FlxA PF14282.1 AAS52546.1 - 0.29 11.0 7.1 3 7.8 0.4 2.3 2 0 0 2 2 2 0 FlxA-like protein DUF948 PF06103.6 AAS52546.1 - 0.3 10.9 3.2 1.1 9.1 0.3 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4200 PF13863.1 AAS52546.1 - 0.51 10.3 4.9 0.3 11.0 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CENP-Q PF13094.1 AAS52546.1 - 0.53 10.2 4.9 0.47 10.4 0.5 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3450 PF11932.3 AAS52546.1 - 0.91 8.7 6.3 0.23 10.6 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Osmo_CC PF08946.5 AAS52546.1 - 1.1 9.3 4.1 2.1 8.4 0.2 2.7 2 1 1 3 3 3 0 Osmosensory transporter coiled coil DUF2681 PF10883.3 AAS52546.1 - 2.1 8.6 6.7 0.48 10.6 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) ATG27 PF09451.5 AAS52547.2 - 2.5e-68 230.2 0.3 5.9e-68 229.0 0.2 1.5 1 1 0 1 1 1 1 Autophagy-related protein 27 DUF1344 PF07076.6 AAS52547.2 - 0.065 12.8 0.1 0.17 11.4 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1344) Baculo_gp64 PF03273.8 AAS52547.2 - 0.1 10.7 0.0 0.16 10.1 0.0 1.2 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family Ribosomal_L22 PF00237.14 AAS52548.2 - 4.7e-33 113.2 0.1 8.2e-33 112.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CASP_C PF08172.7 AAS52549.1 - 4e-72 242.2 2.2 4e-72 242.2 1.5 4.3 3 2 1 5 5 5 1 CASP C terminal Chordopox_E11 PF06138.7 AAS52549.1 - 0.011 15.8 0.1 2.3 8.3 0.0 3.1 3 0 0 3 3 3 0 Chordopoxvirus E11 protein ADIP PF11559.3 AAS52549.1 - 0.011 15.5 2.0 0.011 15.5 1.4 6.6 4 1 2 6 6 6 0 Afadin- and alpha -actinin-Binding Lectin_N PF03954.9 AAS52549.1 - 0.03 13.7 24.0 2.3 7.5 5.2 5.3 4 1 0 4 4 4 0 Hepatic lectin, N-terminal domain DUF972 PF06156.8 AAS52549.1 - 0.038 14.3 0.3 0.038 14.3 0.2 6.7 4 1 3 7 7 7 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 AAS52549.1 - 0.061 13.1 0.4 0.061 13.1 0.2 5.3 5 1 0 5 5 5 0 Protein of unknown function (DUF1664) Metal_resist PF13801.1 AAS52549.1 - 0.09 12.7 0.3 0.09 12.7 0.2 3.6 4 0 0 4 4 4 0 Heavy-metal resistance Reo_sigmaC PF04582.7 AAS52549.1 - 0.3 10.2 21.1 0.86 8.7 0.3 4.9 3 1 2 5 5 5 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 AAS52549.1 - 1.9 8.3 62.1 0.29 10.9 1.9 6.4 4 2 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SWIRM PF04433.12 AAS52550.2 - 9.8e-33 112.1 0.2 2.1e-32 111.1 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 AAS52550.2 - 4.5e-07 29.8 0.0 1.1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AAS52550.2 - 2.1e-06 27.6 0.1 4.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain KRE9 PF05390.6 AAS52551.2 - 5.9e-29 100.5 6.6 1e-28 99.7 4.6 1.3 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 AAS52551.2 - 1.8e-07 31.5 0.0 4.9e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Rep_fac-A_3 PF08661.6 AAS52552.1 - 2.1e-30 104.8 0.0 2.4e-30 104.6 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Peptidase_M20 PF01546.23 AAS52553.1 - 6.4e-26 91.0 0.0 1.1e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AAS52553.1 - 1.3e-15 57.1 0.0 3.7e-15 55.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain STE3 PF02076.10 AAS52554.1 - 1.5e-91 306.4 16.4 1.8e-91 306.1 11.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor Syndecan PF01034.15 AAS52554.1 - 0.011 15.3 1.3 5.3 6.7 0.4 2.8 2 0 0 2 2 2 0 Syndecan domain DUF2401 PF10287.4 AAS52555.2 - 3.3e-83 278.7 0.0 4.3e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 AAS52555.2 - 5.9e-26 90.4 0.0 1.2e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) DUF2838 PF10998.3 AAS52556.1 - 0.32 10.9 5.0 0.55 10.1 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) SRI PF08236.6 AAS52557.2 - 2.5e-29 101.0 5.8 2.5e-29 101.0 4.0 2.3 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 AAS52557.2 - 5.3e-22 78.8 0.4 5.3e-22 78.8 0.3 3.8 3 2 0 3 3 3 1 SET domain DUF3498 PF12004.3 AAS52557.2 - 2.2 7.3 18.7 3.3 6.7 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Wzy_C PF04932.10 AAS52558.2 - 0.061 13.1 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 O-Antigen ligase Zip PF02535.17 AAS52559.2 - 1.2e-22 80.3 3.4 5.4e-22 78.2 2.4 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter MFS_1 PF07690.11 AAS52559.2 - 0.062 12.0 13.4 0.087 11.5 2.4 2.1 2 0 0 2 2 2 0 Major Facilitator Superfamily AA_permease PF00324.16 AAS52560.1 - 1.3e-50 172.1 36.9 1.6e-50 171.8 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS52560.1 - 1.9e-29 102.4 35.9 2.4e-29 102.1 24.8 1.1 1 0 0 1 1 1 1 Amino acid permease GTP_EFTU PF00009.22 AAS52561.1 - 6.6e-33 113.7 0.0 9.6e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 AAS52561.1 - 2.4e-16 59.3 0.0 6.1e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 AAS52561.1 - 7.4e-16 57.7 0.0 1.7e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV Miro PF08477.8 AAS52561.1 - 4.3e-06 27.2 0.0 9.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 AAS52561.1 - 1.3e-05 25.2 0.0 2.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AAS52561.1 - 2.3e-05 24.3 0.0 4.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 AAS52561.1 - 9e-05 22.2 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Dynamin_N PF00350.18 AAS52561.1 - 0.0018 18.0 0.0 0.28 10.9 0.0 2.3 2 0 0 2 2 2 1 Dynamin family SRPRB PF09439.5 AAS52561.1 - 0.047 12.9 0.0 1.1 8.4 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Ebp2 PF05890.7 AAS52562.2 - 8.2e-85 284.3 23.0 8.2e-85 284.3 15.9 2.7 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 polyprenyl_synt PF00348.12 AAS52563.1 - 1.2e-80 270.0 0.0 1.4e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase UcrQ PF02939.11 AAS52564.1 - 7e-38 128.3 1.4 8.1e-38 128.1 0.9 1.0 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 AAS52564.1 - 0.11 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2741) Pkinase PF00069.20 AAS52565.1 - 2.1e-38 131.9 0.0 1.6e-26 92.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52565.1 - 1e-20 73.9 0.0 1.1e-16 60.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AAS52565.1 - 0.001 18.1 0.0 0.081 11.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Ribosomal_L14 PF00238.14 AAS52566.1 - 2.2e-43 146.8 2.4 2.5e-43 146.7 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.20 AAS52567.1 - 7.6e-51 172.7 0.0 1.2e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52567.1 - 1.2e-17 63.8 0.0 4e-17 62.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS52567.1 - 0.00069 18.6 0.0 0.0021 17.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 AAS52567.1 - 0.024 14.2 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 AAS52567.1 - 0.03 13.3 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LrgB PF04172.11 AAS52568.2 - 8.2e-21 74.1 8.6 8.2e-21 74.1 6.0 3.3 4 1 0 4 4 4 1 LrgB-like family LrgA PF03788.9 AAS52568.2 - 0.0055 16.3 5.3 0.0055 16.3 3.7 2.7 3 0 0 3 3 3 1 LrgA family MKT1_N PF12247.3 AAS52568.2 - 0.026 14.8 0.1 0.078 13.3 0.0 1.8 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication DUF2852 PF11014.3 AAS52568.2 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) SecE PF00584.15 AAS52568.2 - 0.19 11.3 0.0 0.19 11.3 0.0 3.2 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex DUF1049 PF06305.6 AAS52568.2 - 0.25 10.8 5.1 0.8 9.2 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) L51_S25_CI-B8 PF05047.11 AAS52569.1 - 3.2e-13 49.1 0.0 4.9e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Pkinase PF00069.20 AAS52570.2 - 5.8e-71 238.6 0.0 7.1e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52570.2 - 2.1e-40 138.4 0.0 3e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS52570.2 - 8.9e-06 24.8 0.0 1.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 AAS52570.2 - 0.066 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 AAS52570.2 - 0.08 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AAS52570.2 - 0.12 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.11 AAS52571.1 - 1.3e-20 73.4 27.0 1.3e-20 73.4 18.7 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily PigN PF04987.9 AAS52572.2 - 8.3e-142 472.9 43.3 1.2e-141 472.4 30.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 AAS52572.2 - 1.8e-13 50.5 0.3 2.5e-10 40.2 0.0 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 AAS52572.2 - 1.8e-11 43.8 0.2 3.1e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 AAS52572.2 - 0.00022 20.6 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily DnaJ PF00226.26 AAS52573.1 - 1.3e-19 69.7 0.5 2.6e-19 68.7 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain PIR PF00399.14 AAS52574.1 - 2.1e-68 223.5 102.3 5.2e-08 31.9 3.2 9.4 9 0 0 9 9 9 9 Yeast PIR protein repeat DUF4098 PF13345.1 AAS52574.1 - 0.33 10.9 6.1 1.4 8.9 0.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4098) UPF0444 PF15475.1 AAS52574.1 - 6.1 6.9 12.9 40 4.3 2.1 3.4 1 1 1 2 2 2 0 Transmembrane protein C12orf23, UPF0444 PIR PF00399.14 AAS52575.1 - 1.2e-05 24.4 11.4 5.5e-05 22.3 1.5 2.6 2 0 0 2 2 2 2 Yeast PIR protein repeat NAP PF00956.13 AAS52576.2 - 7e-82 274.2 0.0 7e-82 274.2 0.0 1.4 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) HCMVantigenic_N PF12154.3 AAS52577.1 - 0.088 12.7 0.9 0.27 11.1 0.1 2.2 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV Vps35 PF03635.12 AAS52578.1 - 1.8e-287 955.5 11.4 2.1e-287 955.3 7.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 6PF2K PF01591.13 AAS52579.2 - 5.7e-87 290.4 0.0 8.6e-87 289.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 AAS52579.2 - 9e-32 110.3 0.1 2.2e-31 109.0 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 AAS52579.2 - 2.3e-06 27.5 0.0 4.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AAS52579.2 - 0.0014 19.4 0.4 0.02 15.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain Peptidase_S64 PF08192.6 AAS52580.1 - 1e-269 896.7 0.0 1.1e-269 896.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S64 zf-RING_2 PF13639.1 AAS52581.2 - 6.1e-05 22.7 3.5 0.00018 21.2 2.5 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AAS52581.2 - 0.0028 17.2 3.9 0.0063 16.1 2.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS52581.2 - 0.054 13.5 3.4 0.15 12.1 2.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AAS52581.2 - 0.098 12.7 1.3 0.23 11.5 0.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Fcf1 PF04900.7 AAS52583.1 - 1.4e-37 127.8 1.3 1.4e-37 127.8 0.1 1.6 2 0 0 2 2 2 1 Fcf1 DUF4112 PF13430.1 AAS52584.1 - 2.1e-31 107.9 1.6 2.7e-31 107.6 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) HCV_core PF01542.13 AAS52584.1 - 0.1 13.0 2.2 1.8 9.0 0.1 2.2 2 0 0 2 2 2 0 Hepatitis C virus core protein ING PF12998.2 AAS52585.1 - 8.6e-20 70.9 5.4 1.7e-19 70.0 3.7 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 AAS52585.1 - 1.6e-10 40.5 8.9 3.2e-10 39.5 6.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 AAS52585.1 - 0.0037 17.3 1.0 0.0037 17.3 0.7 1.8 2 0 0 2 2 2 1 PHD-like zinc-binding domain Glyco_hydro_20 PF00728.17 AAS52585.1 - 0.16 11.1 0.8 0.33 10.0 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 20, catalytic domain zf-C4_Topoisom PF01396.14 AAS52585.1 - 0.3 10.6 4.8 6.7 6.3 0.3 2.6 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger MatE PF01554.13 AAS52586.2 - 2.8e-64 215.6 22.3 7.3e-35 119.9 5.1 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 AAS52586.2 - 0.00011 22.0 6.2 0.00011 22.0 4.3 4.0 4 0 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Abhydrolase_1 PF00561.15 AAS52587.2 - 4.1e-18 65.7 0.1 9.4e-17 61.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AAS52587.2 - 1.8e-09 37.8 0.0 8.2e-09 35.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AAS52587.2 - 0.042 13.6 0.0 0.91 9.2 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_S15 PF00312.17 AAS52588.1 - 2.8e-25 87.8 0.2 6.4e-25 86.7 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 AAA_26 PF13500.1 AAS52588.1 - 0.071 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3487 PF11990.3 AAS52588.1 - 0.14 11.5 0.3 0.33 10.3 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) Gar1 PF04410.9 AAS52589.1 - 8.2e-44 148.7 0.1 8.2e-44 148.7 0.1 2.1 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region MMR_HSR1 PF01926.18 AAS52590.1 - 2.1e-14 53.4 0.0 4.1e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 AAS52590.1 - 8.4e-07 28.3 0.0 1.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 AAS52590.1 - 1.3e-06 27.8 0.0 2.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AAS52590.1 - 5.3e-06 26.3 0.0 0.092 12.5 0.0 2.4 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.5 AAS52590.1 - 2.1e-05 23.8 0.0 3.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 AAS52590.1 - 0.0001 21.7 0.0 0.00096 18.6 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.13 AAS52590.1 - 0.012 14.6 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Septin Arf PF00025.16 AAS52590.1 - 0.024 13.9 0.0 0.051 12.8 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family AIG1 PF04548.11 AAS52590.1 - 0.032 13.3 0.0 0.058 12.4 0.0 1.5 1 0 0 1 1 1 0 AIG1 family IIGP PF05049.8 AAS52590.1 - 0.035 12.9 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 AAS52590.1 - 0.036 14.3 0.1 0.091 13.0 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Miro PF08477.8 AAS52590.1 - 0.047 14.1 0.0 0.85 10.1 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 AAS52590.1 - 0.077 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IBN_N PF03810.14 AAS52591.1 - 0.034 14.0 0.3 0.34 10.8 0.0 3.0 3 0 0 3 3 3 0 Importin-beta N-terminal domain DUF479 PF04336.7 AAS52591.1 - 1 9.4 6.5 4.8 7.3 0.7 3.1 2 0 0 2 2 2 0 Protein of unknown function, DUF479 Brix PF04427.13 AAS52592.1 - 1.9e-42 145.1 1.8 3e-42 144.4 1.2 1.3 1 0 0 1 1 1 1 Brix domain RhoGEF PF00621.15 AAS52593.1 - 3.6e-11 43.2 0.2 9.1e-11 41.9 0.1 1.7 1 0 0 1 1 1 1 RhoGEF domain PseudoU_synth_2 PF00849.17 AAS52594.2 - 2.1e-31 108.9 0.0 4.3e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.17 AAS52594.2 - 1.3e-17 63.2 0.1 3e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Exo_endo_phos PF03372.18 AAS52595.2 - 2.8e-16 60.2 0.2 3.3e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Git3 PF11710.3 AAS52596.2 - 4.5e-83 277.7 7.3 7.6e-83 277.0 5.1 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 AAS52596.2 - 2.6e-33 113.6 5.7 3e-33 113.4 2.8 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Inositol_P PF00459.20 AAS52597.1 - 5.9e-52 176.6 0.4 1.3e-51 175.4 0.3 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family tRNA_Me_trans PF03054.11 AAS52598.2 - 1.4e-115 385.6 0.0 1.6e-115 385.4 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 AAS52598.2 - 0.00013 21.5 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 AAS52598.2 - 0.0092 14.9 0.1 0.11 11.4 0.0 2.1 2 0 0 2 2 2 1 NAD synthase DEAD PF00270.24 AAS52599.1 - 1.3e-45 154.9 0.1 2.3e-44 150.8 0.0 2.6 2 1 1 3 3 3 1 DEAD/DEAH box helicase DBP10CT PF08147.7 AAS52599.1 - 6.6e-22 77.0 5.5 6.6e-22 77.0 3.8 2.6 3 0 0 3 3 3 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 AAS52599.1 - 7e-21 73.8 0.0 3.3e-20 71.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AAS52599.1 - 5.4e-05 22.1 0.0 0.00012 21.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3449 PF11931.3 AAS52600.2 - 1.7e-68 229.9 2.6 1.8e-68 229.9 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.3 AAS52600.2 - 0.0026 17.8 3.3 0.032 14.3 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 AAS52600.2 - 0.0051 16.8 0.1 0.86 9.7 0.0 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 AAS52600.2 - 1.2 9.4 3.7 2.2 8.6 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2175 PF09943.4 AAS52600.2 - 7.8 6.6 6.4 5.3 7.1 0.1 3.4 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) CTP_transf_1 PF01148.15 AAS52601.1 - 1.8e-78 263.7 23.4 2.4e-78 263.4 16.2 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Pkinase PF00069.20 AAS52602.1 - 2.4e-62 210.4 0.0 3.3e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52602.1 - 2.1e-31 108.9 0.0 6.8e-31 107.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 AAS52602.1 - 0.0017 18.8 0.2 0.0067 16.9 0.1 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 AAS52602.1 - 0.0033 16.4 0.0 0.028 13.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Mannosyl_trans3 PF11051.3 AAS52603.1 - 3.9e-61 206.7 0.0 5.7e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative ADH_zinc_N PF00107.21 AAS52604.2 - 5.9e-07 29.1 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CtnDOT_TraJ PF07863.6 AAS52604.2 - 0.019 15.4 0.1 0.055 13.9 0.1 1.7 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon ADH_N PF08240.7 AAS52604.2 - 0.022 14.5 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain HLH PF00010.21 AAS52605.1 - 0.00012 21.7 0.2 0.00019 21.0 0.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PLC-beta_C PF08703.5 AAS52605.1 - 0.016 14.9 1.8 0.02 14.6 1.3 1.1 1 0 0 1 1 1 0 PLC-beta C terminal AAA_27 PF13514.1 AAS52605.1 - 0.13 9.8 1.0 0.14 9.7 0.7 1.1 1 0 0 1 1 1 0 AAA domain HeH PF12949.2 AAS52605.1 - 0.19 11.2 0.9 0.75 9.3 0.0 2.3 3 0 0 3 3 3 0 HeH/LEM domain DUF1751 PF08551.5 AAS52606.1 - 3.2e-28 97.9 2.6 3.2e-28 97.9 1.8 1.9 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Ribosomal_L18e PF00828.14 AAS52607.1 - 4.5e-22 78.8 0.4 1e-21 77.6 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 zf-C2H2 PF00096.21 AAS52608.1 - 2.7e-08 33.6 9.2 0.00064 19.9 2.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS52608.1 - 9.7e-05 22.4 9.3 0.012 15.9 1.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AAS52608.1 - 0.00014 21.9 0.2 0.00014 21.9 0.1 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AAS52608.1 - 0.035 14.2 2.0 0.13 12.4 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 AAS52608.1 - 0.24 11.5 0.0 0.24 11.5 0.0 3.0 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 AAS52608.1 - 3.9 7.8 12.3 0.1 12.8 0.7 3.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Phos_pyr_kin PF08543.7 AAS52609.1 - 2.7e-09 36.5 0.0 3.7e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 AAS52609.1 - 1.8e-08 33.8 0.0 3.7e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase CDC27 PF09507.5 AAS52610.1 - 1.4e-06 27.8 13.2 3.5e-05 23.2 0.4 3.2 3 0 0 3 3 3 3 DNA polymerase subunit Cdc27 SpoIIIAH PF12685.2 AAS52610.1 - 0.019 14.4 0.9 0.019 14.4 0.7 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF3213 PF11491.3 AAS52610.1 - 0.12 12.2 1.3 0.81 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) RVP PF00077.15 AAS52610.1 - 0.14 12.0 0.2 0.82 9.6 0.1 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease CTK3_C PF12350.3 AAS52610.1 - 0.64 10.0 6.8 1.1 9.2 4.7 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus TFIIA PF03153.8 AAS52610.1 - 8.4 6.1 12.8 0.15 11.9 2.9 1.9 1 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ATP-synt_C PF00137.16 AAS52611.1 - 2.1e-32 110.7 27.6 2.4e-18 65.7 7.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.3 AAS52611.1 - 1.8 8.2 8.6 0.4 10.2 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Nucleopor_Nup85 PF07575.8 AAS52612.2 - 1.7e-185 617.5 8.8 1.9e-185 617.3 6.1 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin Urb2 PF10441.4 AAS52613.1 - 9.3e-65 218.3 3.5 9.3e-65 218.3 2.5 2.1 2 0 0 2 2 2 1 Urb2/Npa2 family Voltage_CLC PF00654.15 AAS52614.2 - 5.6e-83 278.8 23.9 9.1e-83 278.1 16.5 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 AAS52614.2 - 5.8e-10 38.8 0.0 0.0002 21.0 0.0 2.4 2 0 0 2 2 2 2 CBS domain Ribosomal_L7Ae PF01248.21 AAS52615.1 - 7.3e-28 95.9 0.0 8.7e-28 95.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 AAS52615.1 - 0.0067 16.2 0.0 0.0071 16.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 AAS52615.1 - 0.015 15.0 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain HECT PF00632.20 AAS52617.1 - 3.1e-86 289.4 0.7 2.7e-84 283.0 0.0 2.9 3 0 0 3 3 3 2 HECT-domain (ubiquitin-transferase) UCR_TM PF02921.9 AAS52618.1 - 1.7e-22 79.3 2.5 2.9e-22 78.6 1.7 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 AAS52618.1 - 2e-18 65.7 0.0 3.4e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Transp_cyt_pur PF02133.10 AAS52618.1 - 0.064 11.7 0.1 0.082 11.4 0.1 1.1 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2235 PF09994.4 AAS52619.2 - 2.9e-81 272.8 0.0 3.8e-81 272.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) SNF2_N PF00176.18 AAS52620.2 - 1.3e-75 254.0 0.1 1.9e-75 253.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AAS52620.2 - 7.8e-15 54.5 0.0 2.1e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 AAS52620.2 - 0.00018 20.4 0.0 0.0036 16.1 0.0 2.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_11 PF13086.1 AAS52620.2 - 0.012 15.1 0.8 0.29 10.6 0.0 2.8 3 1 1 4 4 4 0 AAA domain Pet191_N PF10203.4 AAS52621.1 - 1.2e-26 92.4 5.0 1.6e-26 92.1 3.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Rav1p_C PF12234.3 AAS52622.2 - 2.3e-263 875.1 6.9 3.3e-262 871.2 3.8 2.1 2 0 0 2 2 2 2 RAVE protein 1 C terminal WD40 PF00400.27 AAS52622.2 - 0.0051 16.6 5.7 17 5.5 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat HPS3_N PF14761.1 AAS52622.2 - 0.024 14.0 0.0 0.071 12.4 0.0 1.8 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Pro_isomerase PF00160.16 AAS52623.1 - 2.1e-42 144.9 0.1 3.1e-42 144.4 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 AAS52623.1 - 6.2e-12 44.9 5.2 8.3e-07 28.5 0.2 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 AAS52623.1 - 7e-09 34.9 8.2 1.8e-06 27.3 2.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AAS52623.1 - 1.8e-06 27.4 7.0 0.001 18.8 1.5 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 AAS52623.1 - 6.3e-06 26.0 3.1 1.6e-05 24.7 0.9 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 AAS52623.1 - 0.00041 20.9 0.0 0.0011 19.5 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 AAS52623.1 - 0.0048 17.0 5.0 0.016 15.3 3.1 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AAS52623.1 - 0.0058 16.3 10.9 0.012 15.3 1.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 AAS52623.1 - 0.12 12.9 0.9 2.2 8.9 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF357 PF04010.8 AAS52623.1 - 0.14 11.9 1.1 0.36 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF357) Sec7 PF01369.15 AAS52624.2 - 1.5e-62 210.6 2.6 1.5e-62 210.6 1.8 2.0 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 AAS52624.2 - 6.6e-16 58.1 3.8 6.6e-16 58.1 2.6 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mito_carr PF00153.22 AAS52625.1 - 3.6e-15 55.4 1.9 1.3e-09 37.6 0.0 3.3 3 1 0 3 3 3 2 Mitochondrial carrier protein OMPdecase PF00215.19 AAS52626.1 - 4.7e-75 251.8 0.0 5.8e-75 251.5 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family zf-Tim10_DDP PF02953.10 AAS52627.1 - 9.7e-22 76.0 5.8 1.4e-21 75.5 4.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mmp37 PF09139.6 AAS52627.1 - 0.073 12.0 0.2 0.076 12.0 0.2 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Vicilin_N PF04702.7 AAS52627.1 - 0.26 10.9 6.0 0.34 10.5 4.1 1.2 1 0 0 1 1 1 0 Vicilin N terminal region Pepsin-I3 PF06394.8 AAS52627.1 - 0.33 10.6 3.1 0.67 9.6 0.1 2.1 2 1 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain DUF842 PF05811.8 AAS52627.1 - 0.41 10.1 8.4 0.97 8.8 5.8 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) MFS_1 PF07690.11 AAS52628.1 - 1.6e-25 89.6 28.2 2.7e-22 78.9 6.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AAS52628.1 - 1.5e-13 50.1 2.7 1.5e-13 50.1 1.8 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 AAS52628.1 - 2.3e-06 26.3 14.9 0.0018 16.7 4.6 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 AAS52628.1 - 0.00028 19.2 0.3 0.00049 18.4 0.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CENP-B_dimeris PF09026.5 AAS52629.1 - 0.16 12.2 5.9 0.49 10.6 4.1 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2890 PF11081.3 AAS52629.1 - 0.88 9.6 8.7 2.1 8.3 6.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) TPP_enzyme_N PF02776.13 AAS52630.1 - 8e-38 129.6 0.0 1.8e-37 128.4 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 AAS52630.1 - 2.6e-23 82.2 0.0 4.5e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 AAS52630.1 - 6.2e-20 71.3 0.1 1.9e-19 69.7 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain tRNA-synt_2 PF00152.15 AAS52631.1 - 1.9e-65 220.8 0.0 2.6e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AAS52631.1 - 0.00023 20.9 0.0 0.00049 19.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AAS52631.1 - 0.019 14.1 0.1 3.5 6.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) zf-Nse PF11789.3 AAS52632.1 - 2.8e-19 68.3 0.2 1.1e-18 66.4 0.3 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 AAS52632.1 - 0.00012 21.6 2.2 0.003 17.2 1.5 2.5 1 1 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 AAS52632.1 - 0.0013 17.9 0.6 0.0021 17.3 0.0 1.5 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.1 AAS52632.1 - 0.0052 16.5 1.7 0.011 15.6 1.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AAS52632.1 - 0.036 13.7 0.3 0.036 13.7 0.2 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS52632.1 - 0.1 12.6 0.9 0.2 11.7 0.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AAS52632.1 - 0.22 11.6 1.5 0.56 10.3 0.3 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger zf-MIZ PF02891.15 AAS52632.1 - 0.45 10.0 3.5 0.46 10.0 1.6 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger DUF3256 PF11644.3 AAS52633.1 - 0.0038 16.7 0.4 0.0055 16.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3256) DUF87 PF01935.12 AAS52633.1 - 0.11 12.2 1.3 0.21 11.3 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF87 FAM177 PF14774.1 AAS52634.1 - 0.12 12.3 0.4 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 FAM177 family Rho_N PF07498.7 AAS52634.1 - 0.13 11.9 0.9 0.24 11.1 0.6 1.3 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Phosphodiest PF01663.17 AAS52635.1 - 1.5e-80 271.3 0.4 2.1e-80 270.7 0.3 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase YjeF_N PF03853.10 AAS52636.2 - 3.4e-29 101.6 0.2 5.2e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 AAS52636.2 - 1.7e-09 38.1 2.2 3.6e-09 37.1 1.5 1.5 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 AAS52636.2 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Ataxin 2 SM domain Arm PF00514.18 AAS52637.1 - 6.4e-69 225.6 31.4 8.2e-12 44.4 0.0 10.9 11 0 0 11 11 11 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 AAS52637.1 - 4.4e-26 90.9 7.4 1.9e-06 28.0 0.1 7.1 2 2 4 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 AAS52637.1 - 6.2e-17 61.5 14.1 0.00025 21.4 0.2 7.5 6 2 2 8 8 8 5 HEAT-like repeat HEAT PF02985.17 AAS52637.1 - 2.1e-16 58.4 20.0 0.03 14.3 0.1 9.7 10 0 0 10 10 10 5 HEAT repeat Adaptin_N PF01602.15 AAS52637.1 - 1.2e-12 46.9 10.2 1.2e-08 33.7 1.9 2.4 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 AAS52637.1 - 9.6e-10 37.9 11.7 2.3e-07 30.1 2.3 3.4 2 1 0 3 3 3 2 Armadillo-like KAP PF05804.7 AAS52637.1 - 2.1e-09 35.8 1.9 1.2e-08 33.3 1.1 2.1 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) DUF2454 PF10521.4 AAS52637.1 - 5.7e-06 25.5 0.5 0.038 12.9 0.0 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF2454) Cnd1 PF12717.2 AAS52637.1 - 3.9e-05 23.5 2.0 0.22 11.3 0.1 4.8 3 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.9 AAS52637.1 - 9.9e-05 21.5 6.5 0.012 14.7 0.2 3.8 1 1 2 3 3 3 2 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 AAS52637.1 - 0.00022 21.5 0.4 0.63 10.4 0.0 3.7 3 1 0 4 4 2 2 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 AAS52637.1 - 0.0041 17.0 4.9 0.18 11.7 0.1 4.4 2 1 2 5 5 5 1 V-ATPase subunit H DUF1981 PF09324.5 AAS52637.1 - 0.0094 15.4 0.3 8.4 5.9 0.0 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF1981) Phage_30_3 PF08010.6 AAS52637.1 - 0.092 12.2 0.0 0.28 10.6 0.0 1.9 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 LSM PF01423.17 AAS52638.1 - 2e-07 30.4 0.0 2.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain UQ_con PF00179.21 AAS52640.1 - 1.2e-39 134.9 0.1 1.6e-39 134.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AAS52640.1 - 0.03 14.2 0.0 0.061 13.2 0.0 1.7 2 0 0 2 2 2 0 RWD domain Vfa1 PF08432.5 AAS52640.1 - 0.15 12.0 0.7 0.19 11.7 0.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Alpha-amylase_C PF02806.13 AAS52641.1 - 3.6e-26 91.1 0.1 9.3e-26 89.8 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 AAS52641.1 - 2.4e-17 63.3 0.7 1.7e-16 60.5 0.1 2.3 2 1 1 3 3 3 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 AAS52641.1 - 7.8e-14 51.4 0.1 3.5e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_hydro_66 PF13199.1 AAS52641.1 - 0.024 13.0 0.2 0.041 12.2 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 Frag1 PF10277.4 AAS52642.2 - 4.1e-35 121.2 8.3 4.1e-35 121.2 5.8 3.9 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family Sugar_tr PF00083.19 AAS52643.1 - 6e-104 348.1 21.0 7.1e-104 347.8 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AAS52643.1 - 2.2e-22 79.2 25.6 2.3e-21 75.9 13.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2373 PF10180.4 AAS52644.2 - 2.6e-19 68.5 0.0 4.1e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) HAD PF12710.2 AAS52645.2 - 0.0003 21.0 0.0 0.00044 20.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DNA_pol_B_thumb PF14791.1 AAS52646.1 - 2e-15 56.1 0.0 3.6e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 AAS52646.1 - 7.6e-14 51.0 0.0 1.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 AAS52646.1 - 1.9e-13 50.3 0.4 6e-13 48.7 0.2 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.1 AAS52646.1 - 3e-11 43.3 0.0 5.9e-11 42.4 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase beta palm BRCT PF00533.21 AAS52646.1 - 0.0026 17.8 0.0 0.027 14.5 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PGK PF00162.14 AAS52647.2 - 4.6e-152 506.0 0.2 5.2e-152 505.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase TauD PF02668.11 AAS52650.2 - 1.7e-46 158.9 0.1 2.2e-46 158.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 AAS52650.2 - 0.00051 20.4 0.1 1.6 9.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF971) CsiD PF08943.5 AAS52650.2 - 0.015 14.1 0.1 1 8.1 0.0 2.1 2 0 0 2 2 2 0 CsiD 2OG-FeII_Oxy_3 PF13640.1 AAS52650.2 - 0.036 14.5 0.1 2.5 8.6 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily GTP_EFTU PF00009.22 AAS52651.1 - 1.9e-35 121.9 4.8 2.2e-34 118.5 3.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 AAS52651.1 - 3.9e-22 78.1 0.0 1.1e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 AAS52651.1 - 1.6e-07 31.3 0.6 5.6e-07 29.5 0.4 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 AAS52651.1 - 5.1e-07 29.7 1.5 0.0016 18.4 0.1 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.10 AAS52651.1 - 5.8e-07 29.0 0.6 1.7e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region Miro PF08477.8 AAS52651.1 - 1.3e-05 25.7 1.5 2.3e-05 24.8 0.2 2.1 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 AAS52651.1 - 0.0021 17.8 0.2 1.4 8.7 0.1 2.7 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.5 AAS52651.1 - 0.0025 17.0 0.2 0.0051 16.0 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AAS52651.1 - 0.0034 16.7 0.1 0.0065 15.8 0.1 1.5 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.13 AAS52651.1 - 0.0066 15.7 2.0 0.053 12.7 1.4 2.5 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 AAS52651.1 - 0.038 13.4 1.5 0.14 11.6 1.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PDCD2_C PF04194.8 AAS52652.2 - 4.8e-46 156.3 0.2 6.3e-43 146.2 0.0 2.3 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain ABC_tran PF00005.22 AAS52653.1 - 6.3e-46 156.0 6.9 8.5e-23 81.1 0.0 3.4 4 0 0 4 4 3 2 ABC transporter ABC_tran_2 PF12848.2 AAS52653.1 - 7e-19 67.4 10.5 7e-19 67.4 7.3 3.3 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 AAS52653.1 - 1.3e-18 68.0 12.6 9.1e-07 29.1 0.1 5.2 4 2 0 5 5 5 3 AAA domain SMC_N PF02463.14 AAS52653.1 - 9.2e-11 41.3 0.2 0.0016 17.7 0.1 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 AAS52653.1 - 2.1e-09 38.2 2.0 0.00014 22.6 0.1 3.6 4 0 0 4 4 2 2 AAA domain DUF258 PF03193.11 AAS52653.1 - 2.4e-07 30.0 0.0 0.021 13.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 AAS52653.1 - 3.6e-07 30.2 0.0 0.037 13.9 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AAS52653.1 - 3.6e-07 30.3 2.6 0.0019 18.2 0.1 3.1 4 0 0 4 4 2 2 AAA ATPase domain AAA_22 PF13401.1 AAS52653.1 - 3.7e-07 30.3 0.0 0.037 14.1 0.0 3.3 3 1 0 3 3 2 2 AAA domain Miro PF08477.8 AAS52653.1 - 1.4e-06 28.7 0.0 0.14 12.6 0.0 3.3 2 1 0 2 2 2 2 Miro-like protein AAA PF00004.24 AAS52653.1 - 1.5e-06 28.4 0.4 0.13 12.4 0.0 4.3 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AAS52653.1 - 1.6e-06 27.8 0.1 0.011 15.3 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 AAS52653.1 - 2.4e-06 27.8 10.9 0.17 12.1 0.3 5.4 5 2 0 5 5 5 2 AAA domain AAA_29 PF13555.1 AAS52653.1 - 9.6e-06 25.0 4.0 0.066 12.7 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_14 PF13173.1 AAS52653.1 - 1.2e-05 25.2 0.0 0.17 11.7 0.0 3.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 AAS52653.1 - 1.9e-05 25.1 25.6 0.22 11.8 0.0 5.2 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.1 AAS52653.1 - 2.1e-05 24.4 0.1 0.058 13.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 AAS52653.1 - 3.2e-05 23.8 0.0 0.14 12.1 0.0 3.3 2 1 0 2 2 2 2 50S ribosome-binding GTPase PduV-EutP PF10662.4 AAS52653.1 - 7.2e-05 22.3 0.1 0.13 11.7 0.0 2.8 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 AAS52653.1 - 7.6e-05 22.4 0.0 0.52 10.0 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 AAS52653.1 - 0.0002 20.8 0.1 1.2 8.4 0.1 3.3 3 1 0 3 3 3 2 AAA-like domain SbcCD_C PF13558.1 AAS52653.1 - 0.00041 20.1 0.1 2.2 8.2 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 AAS52653.1 - 0.00046 19.1 0.2 0.6 8.9 0.0 2.7 2 1 0 2 2 2 2 NB-ARC domain RNA_helicase PF00910.17 AAS52653.1 - 0.00048 20.2 0.3 0.77 9.9 0.0 3.1 3 0 0 3 3 2 1 RNA helicase ATP-synt_ab PF00006.20 AAS52653.1 - 0.00058 19.4 0.0 0.3 10.5 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ArgK PF03308.11 AAS52653.1 - 0.0012 17.6 0.0 0.98 8.1 0.0 2.7 2 0 0 2 2 2 2 ArgK protein AAA_25 PF13481.1 AAS52653.1 - 0.0017 17.7 0.0 2.1 7.6 0.0 3.1 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.9 AAS52653.1 - 0.0029 17.3 0.1 3.7 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.14 AAS52653.1 - 0.0053 16.2 0.0 1.7 8.0 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 AAS52653.1 - 0.0053 15.6 0.0 0.11 11.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Pox_A32 PF04665.7 AAS52653.1 - 0.0059 15.9 0.0 0.14 11.4 0.0 2.6 2 0 0 2 2 2 1 Poxvirus A32 protein NTPase_1 PF03266.10 AAS52653.1 - 0.0094 15.6 0.0 2.2 7.9 0.0 2.7 2 0 0 2 2 2 1 NTPase AAA_15 PF13175.1 AAS52653.1 - 0.017 14.1 22.8 0.2 10.6 0.0 5.7 2 1 2 4 4 3 0 AAA ATPase domain SRP54 PF00448.17 AAS52653.1 - 0.019 14.4 0.2 2.2 7.7 0.0 3.3 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain FeoB_N PF02421.13 AAS52653.1 - 0.02 14.1 0.0 4.4 6.5 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Ras PF00071.17 AAS52653.1 - 0.05 12.9 2.8 8.2 5.7 0.0 3.8 4 0 0 4 4 4 0 Ras family FtsK_SpoIIIE PF01580.13 AAS52653.1 - 0.05 13.0 1.4 1.6 8.1 0.0 2.9 4 0 0 4 4 2 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 AAS52653.1 - 0.059 12.8 0.0 1.8 7.9 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 AAS52653.1 - 0.081 12.5 0.1 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 AAS52653.1 - 0.2 11.3 0.0 0.2 11.3 0.0 3.6 4 1 0 4 4 3 0 Archaeal ATPase Dynamin_N PF00350.18 AAS52653.1 - 0.2 11.4 10.2 0.26 11.1 0.0 3.9 3 1 1 4 4 4 0 Dynamin family DUF87 PF01935.12 AAS52653.1 - 1.6 8.4 0.0 1.6 8.4 0.0 5.2 5 1 1 6 6 6 0 Domain of unknown function DUF87 DUF1002 PF06207.6 AAS52653.1 - 4.1 6.6 10.2 0.4 9.9 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) RNB PF00773.14 AAS52654.1 - 2e-95 319.8 0.0 3.1e-95 319.1 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 AAS52654.1 - 5.3e-15 55.6 0.3 1.3e-14 54.4 0.2 1.7 1 0 0 1 1 1 1 PIN domain AA_permease PF00324.16 AAS52655.3 - 2.9e-120 401.8 40.5 3.3e-120 401.6 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS52655.3 - 5.2e-32 110.9 42.1 6.6e-32 110.5 29.2 1.1 1 0 0 1 1 1 1 Amino acid permease UCH PF00443.24 AAS52656.2 - 6.5e-51 173.0 0.0 7.8e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AAS52656.2 - 4.2e-16 59.2 0.2 8.8e-16 58.1 0.2 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 AAS52656.2 - 0.0091 15.3 0.0 0.037 13.4 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family DUF1690 PF07956.6 AAS52657.2 - 2e-51 173.6 5.5 2.4e-51 173.4 3.8 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Cgr1 PF03879.9 AAS52657.2 - 0.34 11.1 5.1 0.61 10.2 3.5 1.3 1 0 0 1 1 1 0 Cgr1 family SUR7 PF06687.7 AAS52658.2 - 4.2e-17 62.4 12.9 6.1e-17 61.8 9.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF2456 PF10445.4 AAS52658.2 - 1.9 8.4 7.1 0.62 10.0 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) SNARE PF05739.14 AAS52659.2 - 6.8e-16 57.7 2.1 6.8e-16 57.7 1.5 1.8 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 AAS52659.2 - 0.00069 19.7 5.5 0.002 18.2 0.0 2.7 1 1 1 2 2 2 1 Syntaxin Mlp PF03304.8 AAS52659.2 - 0.0057 16.6 0.7 0.011 15.7 0.5 1.4 1 0 0 1 1 1 1 Mlp lipoprotein family DSPn PF14671.1 AAS52660.2 - 1.6e-50 170.7 0.0 4.2e-50 169.4 0.0 1.7 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 AAS52660.2 - 6.4e-23 80.8 0.0 6.2e-22 77.6 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AAS52660.2 - 0.00014 21.2 0.4 0.00034 20.0 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 AAS52660.2 - 0.0021 17.5 0.1 0.0041 16.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 AAS52660.2 - 0.01 15.8 0.1 0.028 14.4 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 AAS52660.2 - 0.073 13.3 1.9 0.12 12.5 0.1 2.1 2 1 0 2 2 2 0 Tyrosine phosphatase family Acetyltransf_13 PF13880.1 AAS52661.2 - 3.3e-19 68.3 0.2 6.3e-19 67.4 0.1 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 AAS52661.2 - 7.4e-13 47.8 3.0 1.3e-12 47.0 2.0 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 AAS52661.2 - 0.00015 21.7 0.1 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AAS52661.2 - 0.0061 16.7 0.1 0.013 15.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AAS52661.2 - 0.0067 16.5 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Flo11 PF10182.4 AAS52662.2 - 5.8e-55 185.0 1.2 1.4e-54 183.8 0.8 1.7 1 0 0 1 1 1 1 Flo11 domain PHP PF02811.14 AAS52663.2 - 7e-18 65.0 0.0 1.3e-17 64.0 0.0 1.4 1 1 0 1 1 1 1 PHP domain ProRS-C_1 PF09180.6 AAS52664.1 - 7e-25 86.7 0.8 1.9e-24 85.3 0.6 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 AAS52664.1 - 3e-22 79.0 0.1 4.5e-22 78.4 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AAS52664.1 - 1.8e-19 69.4 0.0 4.5e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 AAS52664.1 - 0.0032 17.3 0.4 0.0063 16.3 0.3 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2 PF00152.15 AAS52665.2 - 8.3e-75 251.6 0.0 1.3e-74 250.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AAS52665.2 - 2.3e-10 40.1 0.0 4.6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.6 AAS52665.2 - 0.038 13.0 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase HR1 PF02185.11 AAS52665.2 - 0.83 9.4 5.5 1.5 8.6 3.8 1.4 1 0 0 1 1 1 0 Hr1 repeat Lyase_1 PF00206.15 AAS52666.1 - 3.5e-98 328.6 0.0 5.4e-98 328.0 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 AAS52666.1 - 6.3e-26 90.2 0.0 1.7e-25 88.9 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF1776 PF08643.5 AAS52667.1 - 1.9e-74 250.4 0.0 2.4e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF500 PF04366.7 AAS52668.1 - 1.4e-45 153.7 0.2 2.7e-45 152.8 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 AAS52668.1 - 9.3e-16 56.9 0.1 1.8e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AAS52668.1 - 2.6e-14 52.5 0.0 5.9e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AAS52668.1 - 1.3e-11 43.7 0.0 2.7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RRM_1 PF00076.17 AAS52669.2 - 1.7e-47 158.8 8.7 1.7e-17 62.7 0.4 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS52669.2 - 1.9e-29 101.4 1.6 2.6e-10 40.1 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS52669.2 - 3.2e-23 81.3 1.4 1.7e-07 30.9 0.6 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AAS52669.2 - 6.4e-05 22.7 0.2 0.92 9.3 0.0 3.8 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.1 AAS52669.2 - 0.00044 19.9 0.0 0.43 10.3 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nuf2 PF03800.9 AAS52670.1 - 1.4e-45 154.8 0.2 1.4e-45 154.8 0.1 2.3 2 1 0 2 2 2 1 Nuf2 family Phage_X PF05155.10 AAS52670.1 - 0.054 13.4 0.0 0.28 11.1 0.0 2.3 1 0 0 1 1 1 0 Phage X family FlaC_arch PF05377.6 AAS52670.1 - 8.3 6.3 10.4 1.7 8.6 0.4 4.1 3 1 0 4 4 4 0 Flagella accessory protein C (FlaC) zf-met PF12874.2 AAS52671.1 - 2.8e-06 27.3 1.5 5.5e-06 26.3 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AAS52671.1 - 0.034 14.2 0.2 0.068 13.2 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF592 PF04574.8 AAS52672.1 - 6.4e-68 227.1 0.1 1.1e-67 226.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) SIR2 PF02146.12 AAS52672.1 - 1.6e-62 210.3 0.0 2.7e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 AAS52672.1 - 0.0026 17.5 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Paired_CXXCH_1 PF09699.5 AAS52672.1 - 0.071 12.6 0.2 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) HLH PF00010.21 AAS52673.1 - 6.6e-16 57.7 0.0 1e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MRF_C1 PF13887.1 AAS52673.1 - 0.25 10.4 1.4 0.39 9.7 0.0 1.9 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 AAA PF00004.24 AAS52674.1 - 1.4e-40 138.5 0.0 2.2e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AAS52674.1 - 1.8e-06 28.1 0.2 0.00043 20.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 AAS52674.1 - 6.9e-06 26.0 0.0 1.8e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 AAS52674.1 - 1.4e-05 24.1 0.0 2.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 AAS52674.1 - 3.8e-05 23.4 0.2 0.00019 21.1 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AAS52674.1 - 0.00011 22.2 0.0 0.0032 17.4 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 AAS52674.1 - 0.00088 18.3 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 AAS52674.1 - 0.001 19.0 0.1 0.0034 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AAS52674.1 - 0.0022 17.9 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AAS52674.1 - 0.0045 17.7 0.2 0.012 16.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AAS52674.1 - 0.0066 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 AAS52674.1 - 0.0072 16.6 0.1 0.023 15.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 AAS52674.1 - 0.0074 16.0 0.3 0.015 15.0 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 AAS52674.1 - 0.0097 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 AAS52674.1 - 0.01 15.2 1.6 0.23 10.8 0.3 2.3 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AAS52674.1 - 0.012 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 AAS52674.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 AAS52674.1 - 0.018 13.7 0.0 0.035 12.8 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus NB-ARC PF00931.17 AAS52674.1 - 0.021 13.6 0.0 0.049 12.4 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 AAS52674.1 - 0.022 14.5 0.4 0.19 11.3 0.0 2.5 3 0 0 3 3 2 0 NTPase RNA_helicase PF00910.17 AAS52674.1 - 0.029 14.5 0.0 0.087 13.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase NACHT PF05729.7 AAS52674.1 - 0.03 13.9 0.1 0.32 10.6 0.0 2.2 1 1 0 2 2 2 0 NACHT domain KaiC PF06745.8 AAS52674.1 - 0.034 13.2 0.2 0.41 9.7 0.1 2.3 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.16 AAS52674.1 - 0.05 12.7 0.1 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 AAS52674.1 - 0.055 13.0 0.2 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 AAS52674.1 - 0.058 12.6 0.2 0.19 10.9 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 AAS52674.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PP2C PF00481.16 AAS52675.2 - 6.3e-73 245.3 0.1 8.6e-73 244.8 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Med2 PF11214.3 AAS52676.1 - 2.2e-32 111.2 6.8 4e-32 110.3 4.7 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 DUF3987 PF13148.1 AAS52676.1 - 0.0039 15.8 3.8 0.0057 15.2 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) PsiA PF06952.6 AAS52676.1 - 0.2 10.7 5.9 0.3 10.1 3.9 1.4 1 1 0 1 1 1 0 PsiA protein Effector_1 PF04518.7 AAS52676.1 - 2.1 7.2 11.6 4.2 6.2 7.8 1.6 1 1 1 2 2 2 0 Effector from type III secretion system ATP-synt_DE_N PF02823.11 AAS52677.1 - 4.1e-20 71.3 0.3 5.8e-20 70.8 0.2 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Rad21_Rec8_N PF04825.8 AAS52678.2 - 1.6e-25 89.2 0.1 3.4e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 AAS52678.2 - 5.4e-09 35.1 0.0 1.6e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 AAS52678.2 - 0.016 14.7 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 ScpA/B protein DRIM PF07539.7 AAS52679.2 - 8.5e-48 161.3 0.5 4.1e-47 159.1 0.4 2.4 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 AAS52679.2 - 0.095 12.8 7.0 37 4.7 0.0 7.1 7 0 0 7 7 7 0 HEAT repeat HMG_box PF00505.14 AAS52680.2 - 6e-16 58.4 1.8 1.1e-15 57.6 1.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AAS52680.2 - 1e-13 51.4 0.7 1.8e-13 50.6 0.5 1.4 1 0 0 1 1 1 1 HMG-box domain DUF155 PF02582.9 AAS52681.1 - 1.6e-61 207.2 2.0 3.8e-61 206.0 1.4 1.6 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 AAS52681.1 - 0.018 15.2 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 SOG2 PF10428.4 AAS52681.1 - 0.051 12.2 0.7 0.092 11.3 0.5 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Histone PF00125.19 AAS52682.1 - 3.5e-26 91.1 0.0 4.8e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AAS52682.1 - 4.1e-06 26.7 0.0 6.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AAS52683.1 - 2.2e-22 78.9 0.3 3.1e-22 78.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AAS52683.1 - 6.9e-06 26.0 0.1 6.9e-06 26.0 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 AAS52683.1 - 0.0015 18.7 0.0 0.0027 17.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 AAS52683.1 - 0.033 12.8 2.1 0.04 12.5 1.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RP-C PF03428.8 AAS52683.1 - 0.065 12.6 0.2 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 AAS52683.1 - 0.11 12.9 0.5 0.15 12.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) DUF77 PF01910.12 AAS52684.1 - 1.8e-31 107.6 0.1 2e-31 107.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 DUF1341 PF07071.6 AAS52684.1 - 0.026 14.0 0.0 0.028 13.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1341) DUF2102 PF09875.4 AAS52684.1 - 0.031 13.8 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) Trehalase PF01204.13 AAS52685.1 - 2.9e-185 616.7 0.0 3.5e-185 616.5 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 AAS52685.1 - 5.1e-17 60.8 0.3 8.4e-17 60.1 0.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Ran_BP1 PF00638.13 AAS52686.2 - 1e-54 183.8 1.1 1.5e-54 183.2 0.8 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 AAS52686.2 - 1.8e-05 24.4 0.8 0.00022 20.8 0.6 2.1 1 1 0 1 1 1 1 WH1 domain DUF4637 PF15470.1 AAS52686.2 - 4.9 6.7 8.1 3.9e+02 0.5 5.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) Prenyltransf PF01255.14 AAS52687.1 - 2.6e-75 252.3 0.0 3.1e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase polyprenyl_synt PF00348.12 AAS52688.2 - 4.9e-49 166.5 0.0 3.2e-22 78.6 0.0 3.0 3 0 0 3 3 3 3 Polyprenyl synthetase DCD PF06559.6 AAS52688.2 - 0.019 13.3 0.0 0.032 12.6 0.0 1.2 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Mannosyl_trans2 PF04188.8 AAS52689.1 - 3.2e-67 227.3 32.6 6.5e-65 219.7 22.6 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) RCR PF12273.3 AAS52690.1 - 2.4e-33 115.4 2.0 3.4e-33 114.9 1.4 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.5 AAS52690.1 - 2.2 7.6 4.1 4 6.8 2.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Aldedh PF00171.17 AAS52691.1 - 4.3e-158 526.4 0.0 4.9e-158 526.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 AAS52691.1 - 0.0078 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) Rad51 PF08423.6 AAS52692.1 - 3.1e-27 95.1 0.0 5.4e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 AAS52692.1 - 1e-07 31.5 0.0 2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 AAS52692.1 - 1.4e-05 24.3 0.0 2.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 KaiC RecA PF00154.16 AAS52692.1 - 0.00014 21.0 0.7 0.00038 19.6 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein CobU PF02283.11 AAS52692.1 - 0.0078 15.6 4.4 0.015 14.7 0.0 3.0 3 0 0 3 3 3 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AIF_C PF14721.1 AAS52692.1 - 0.086 13.0 0.7 0.23 11.6 0.5 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Maf1 PF09174.5 AAS52693.1 - 4.2e-51 173.3 2.1 1.7e-48 164.8 0.0 2.3 2 0 0 2 2 2 2 Maf1 regulator Sel1 PF08238.7 AAS52694.2 - 1.4e-07 31.8 5.1 0.00094 19.7 0.5 4.1 4 0 0 4 4 4 2 Sel1 repeat Tcp11 PF05794.8 AAS52695.2 - 2e-124 415.6 4.8 4.7e-124 414.4 3.3 1.6 1 1 0 1 1 1 1 T-complex protein 11 Histone PF00125.19 AAS52696.2 - 2.9e-14 52.9 0.2 3.5e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 AAS52696.2 - 5.5e-05 23.0 0.2 8e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 AAS52696.2 - 6.6e-05 23.0 0.1 9.7e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AAS52696.2 - 8e-05 22.6 0.1 0.00015 21.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 AAS52696.2 - 0.003 16.8 0.0 0.0032 16.7 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 AAS52696.2 - 0.0046 16.6 0.0 0.0059 16.3 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 AAS52696.2 - 0.036 14.3 0.1 0.062 13.5 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 AAS52696.2 - 0.14 11.9 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 AAS52697.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 AAS52697.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AAS52697.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 AAS52697.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated PRAI PF00697.17 AAS52698.1 - 1e-50 172.0 0.0 1.2e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Aldolase PF01081.14 AAS52698.1 - 0.0018 17.4 0.9 0.0047 16.1 0.0 2.0 2 1 0 2 2 2 1 KDPG and KHG aldolase Pyrophosphatase PF00719.14 AAS52699.1 - 1.3e-53 180.6 0.1 1.7e-53 180.2 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase zf-Apc11 PF12861.2 AAS52700.1 - 7.6e-41 137.8 6.4 9.9e-41 137.5 4.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 AAS52700.1 - 1.4e-28 98.7 8.4 2e-28 98.3 5.8 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 AAS52700.1 - 1.8e-06 27.6 21.2 6.2e-06 25.9 13.6 2.7 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 AAS52700.1 - 0.00016 21.3 13.0 0.0036 17.0 9.6 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 AAS52700.1 - 0.0014 18.1 11.4 0.0028 17.1 0.3 3.1 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 AAS52700.1 - 0.019 14.9 14.7 0.16 11.9 10.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AAS52700.1 - 0.032 13.8 13.2 1.4 8.6 9.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HIT PF04438.11 AAS52700.1 - 0.039 13.5 3.2 0.039 13.5 2.3 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-C3HC4_4 PF15227.1 AAS52700.1 - 0.055 13.3 4.4 0.055 13.3 3.0 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-HC5HC2H PF13771.1 AAS52700.1 - 0.059 13.5 7.2 0.16 12.1 5.1 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain Opy2 PF09463.5 AAS52700.1 - 0.16 12.1 11.7 0.086 12.9 4.5 2.3 2 0 0 2 2 2 0 Opy2 protein zf-C3HC4 PF00097.20 AAS52700.1 - 0.17 11.6 19.2 0.2 11.3 11.5 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 AAS52700.1 - 0.72 9.8 8.5 1.1 9.3 5.0 1.9 1 1 1 2 2 2 0 PHD-zinc-finger like domain FANCL_C PF11793.3 AAS52700.1 - 0.8 9.7 20.2 2.5 8.1 11.9 3.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.6 AAS52700.1 - 0.84 9.6 13.2 0.98 9.4 7.7 2.2 1 1 1 2 2 2 0 RING-like domain zf-Nse PF11789.3 AAS52700.1 - 1.2 8.6 5.2 2.4 7.7 3.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RecR PF02132.10 AAS52700.1 - 5.9 6.4 6.2 6.1 6.3 0.3 2.9 3 0 0 3 3 3 0 RecR protein Glutaredoxin PF00462.19 AAS52701.2 - 1.7e-11 43.9 0.0 2.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF3400 PF11880.3 AAS52701.2 - 0.059 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) ExbD PF02472.11 AAS52701.2 - 0.12 12.3 0.2 0.33 10.9 0.1 1.7 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Mannosyl_trans3 PF11051.3 AAS52702.1 - 2.7e-85 286.0 0.0 4.2e-85 285.3 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative NatB_MDM20 PF09797.4 AAS52703.1 - 6.6e-69 232.3 2.2 1e-68 231.6 1.6 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Brix PF04427.13 AAS52704.1 - 4.3e-42 143.9 0.2 5.3e-42 143.6 0.2 1.1 1 0 0 1 1 1 1 Brix domain DUF2611 PF11022.3 AAS52705.1 - 9.1e-24 83.3 0.0 9.8e-24 83.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Peptidase_S10 PF00450.17 AAS52706.1 - 2.5e-126 422.2 0.3 3.1e-126 421.8 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 AAS52706.1 - 9.3e-05 22.4 0.0 0.0015 18.4 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Calici_coat_C PF08435.6 AAS52706.1 - 0.074 12.3 0.1 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal EcoRII-N PF09217.5 AAS52706.1 - 0.078 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease EcoRII, N-terminal SIN1 PF05422.7 AAS52707.2 - 1.3e-27 96.5 0.1 4.7e-14 51.8 0.0 2.2 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) PH PF00169.24 AAS52707.2 - 0.047 13.9 0.2 0.19 11.9 0.1 2.1 2 0 0 2 2 2 0 PH domain RNase_T PF00929.19 AAS52708.1 - 1.4e-26 93.7 0.0 2.6e-26 92.8 0.0 1.5 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 AAS52708.1 - 0.014 14.8 0.0 0.05 13.0 0.0 1.8 1 1 0 1 1 1 0 3'-5' exonuclease DUF2201_N PF13203.1 AAS52708.1 - 5.9 5.9 8.9 9.2 5.3 6.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain RasGAP PF00616.14 AAS52709.2 - 4.4e-37 127.6 1.1 1.7e-36 125.7 0.0 2.7 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase DUF3321 PF11968.3 AAS52710.1 - 3.4e-76 255.7 0.0 4.6e-76 255.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 AAS52710.1 - 4.2e-05 23.3 0.0 7.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DEAD PF00270.24 AAS52711.1 - 4.8e-35 120.5 0.0 1.1e-34 119.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS52711.1 - 2e-24 85.2 0.0 1.6e-23 82.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain eRF1_2 PF03464.10 AAS52712.1 - 2.9e-45 153.8 0.2 5e-45 153.0 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 AAS52712.1 - 1.2e-38 131.8 0.8 2.9e-38 130.5 0.5 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 AAS52712.1 - 6.6e-28 96.9 0.1 1.2e-27 96.0 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 ZZ PF00569.12 AAS52713.2 - 2.5e-12 46.1 40.0 1.5e-06 27.5 6.4 4.6 3 2 1 4 4 4 3 Zinc finger, ZZ type ATG19_autophagy PF12744.2 AAS52713.2 - 5e-11 42.3 0.0 1.9e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding MDMPI_N PF11716.3 AAS52713.2 - 0.047 14.1 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain DUF4546 PF15079.1 AAS52713.2 - 0.46 9.6 1.4 1.4 7.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4546) DUF221 PF02714.10 AAS52714.1 - 2.4e-97 325.6 22.2 2.4e-97 325.6 15.4 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AAS52714.1 - 1.4e-38 131.9 2.4 1.4e-38 131.9 1.7 3.7 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 AAS52714.1 - 3.3e-25 87.7 0.1 7.4e-25 86.6 0.1 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 AAS52714.1 - 6.5e-17 61.8 4.5 1.2e-16 60.9 3.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) YopR_core PF09025.5 AAS52714.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 YopR Core Gp_dh_C PF02800.15 AAS52715.2 - 2.7e-74 247.8 0.0 4.3e-74 247.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 AAS52715.2 - 1.1e-59 200.7 0.7 1.8e-59 200.0 0.1 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 AAS52715.2 - 0.019 14.8 1.1 0.039 13.8 0.3 2.1 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 AAS52715.2 - 0.056 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 AAS52716.1 - 4.9e-30 103.7 0.7 7e-30 103.2 0.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AAS52716.1 - 5.1e-30 103.4 0.3 1.2e-29 102.2 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 AAS52716.1 - 1.5e-06 29.1 0.4 2.7e-06 28.2 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ribosomal_S9 PF00380.14 AAS52717.1 - 9.4e-41 138.8 0.5 1.7e-40 138.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 CHASE3 PF05227.8 AAS52717.1 - 0.063 12.9 0.6 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 CHASE3 domain Endonuclease_NS PF01223.18 AAS52717.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease CENP-S PF15630.1 AAS52718.1 - 2e-25 88.7 0.0 2.5e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 AAS52718.1 - 0.00055 19.2 0.1 0.00069 18.9 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 AAS52718.1 - 0.098 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF3337 PF11816.3 AAS52719.2 - 1.7e-70 238.0 0.0 2.7e-69 234.1 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 AAS52719.2 - 7.7e-11 41.4 2.6 0.014 15.2 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat RNA_pol_Rpb5_N PF03871.9 AAS52720.1 - 1.5e-34 118.2 0.4 2.9e-34 117.3 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.14 AAS52720.1 - 1e-33 114.7 0.5 1.9e-33 113.8 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Sof1 PF04158.9 AAS52720.1 - 0.064 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Sof1-like domain RibD_C PF01872.12 AAS52721.1 - 2.1e-34 118.8 0.0 2.4e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Prp19_bind PF06991.6 AAS52722.1 - 2.3e-09 36.9 6.8 4.2e-09 36.0 4.7 1.3 1 0 0 1 1 1 1 Splicing factor, Prp19-binding domain Thioredoxin PF00085.15 AAS52723.2 - 5e-12 45.4 0.0 7.9e-11 41.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin ERp29 PF07749.7 AAS52723.2 - 0.018 15.6 0.1 0.039 14.5 0.0 1.6 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_8 PF13905.1 AAS52723.2 - 0.058 13.5 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.1 AAS52723.2 - 0.063 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Suc_Fer-like PF06999.7 AAS52724.1 - 7.5e-57 192.9 0.0 9.6e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like zf-nanos PF05741.8 AAS52724.1 - 0.069 13.1 1.0 0.16 11.9 0.7 1.6 1 0 0 1 1 1 0 Nanos RNA binding domain CRAL_TRIO PF00650.15 AAS52725.2 - 3.7e-45 153.2 0.0 7.1e-45 152.3 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AAS52725.2 - 1e-12 47.9 0.1 3.2e-12 46.3 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AAS52725.2 - 1.4e-07 31.5 0.0 3.8e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain tRNA-synt_1 PF00133.17 AAS52727.1 - 1e-48 165.7 0.0 1.2e-15 56.5 0.3 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 AAS52727.1 - 3e-26 91.8 0.0 4.8e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 AAS52727.1 - 7.7e-26 90.6 0.0 1.4e-20 73.3 0.0 4.0 3 1 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1d PF00750.14 AAS52727.1 - 0.00012 21.0 0.0 0.00019 20.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) Anticodon_1 PF08264.8 AAS52727.1 - 0.00037 20.2 0.0 0.00074 19.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 AAS52727.1 - 0.0054 15.8 0.0 0.84 8.6 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain SMC_N PF02463.14 AAS52728.1 - 3.3e-28 98.4 0.0 2.1e-27 95.7 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AAS52728.1 - 1e-11 45.5 38.5 1e-11 45.5 26.7 4.6 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.1 AAS52728.1 - 4.6e-06 26.8 7.2 0.015 15.2 3.7 3.2 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 AAS52728.1 - 1.5e-05 24.2 22.8 0.00039 19.5 8.7 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AAS52728.1 - 5e-05 22.7 0.0 0.00012 21.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 AAS52728.1 - 6.5e-05 21.6 62.0 0.014 13.8 8.7 5.0 3 2 2 5 5 5 3 AAA domain DUF869 PF05911.6 AAS52728.1 - 0.0015 16.8 50.7 0.0047 15.2 17.5 2.5 2 1 0 2 2 2 2 Plant protein of unknown function (DUF869) ADIP PF11559.3 AAS52728.1 - 0.0024 17.7 16.1 0.0024 17.7 11.2 6.9 5 2 1 8 8 8 1 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 AAS52728.1 - 0.0057 15.8 7.5 0.59 9.2 0.5 3.0 2 1 1 3 3 3 3 Reovirus sigma C capsid protein SMC_hinge PF06470.8 AAS52728.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain ABC_tran PF00005.22 AAS52728.1 - 0.081 13.2 0.0 0.081 13.2 0.0 5.1 3 2 0 3 3 2 0 ABC transporter DUF3584 PF12128.3 AAS52728.1 - 0.099 9.9 63.2 0.0065 13.8 7.5 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3584) Uso1_p115_head PF04869.9 AAS52729.1 - 2.5e-103 345.1 1.7 3.8e-103 344.5 0.1 2.2 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 AAS52729.1 - 6.9e-14 51.9 24.8 6.9e-14 51.9 17.2 7.0 1 1 6 7 7 5 2 Uso1 / p115 like vesicle tethering protein, C terminal region Myosin_tail_1 PF01576.14 AAS52729.1 - 8.9e-08 30.3 84.7 8.9e-08 30.3 58.7 3.7 1 1 0 2 2 2 1 Myosin tail HEAT_2 PF13646.1 AAS52729.1 - 0.00041 20.5 1.4 0.0061 16.8 0.0 3.6 3 0 0 3 3 3 1 HEAT repeats Reo_sigmaC PF04582.7 AAS52729.1 - 0.0016 17.6 56.5 0.019 14.1 4.6 6.1 1 1 5 6 6 6 4 Reovirus sigma C capsid protein IncA PF04156.9 AAS52729.1 - 0.0022 17.5 127.3 1.3 8.5 6.3 7.2 1 1 5 6 6 6 4 IncA protein GAS PF13851.1 AAS52729.1 - 0.0027 16.9 10.5 0.0027 16.9 7.3 7.2 1 1 5 7 7 6 3 Growth-arrest specific micro-tubule binding IFT57 PF10498.4 AAS52729.1 - 0.004 15.9 9.4 0.004 15.9 6.5 6.1 1 1 5 6 6 6 1 Intra-flagellar transport protein 57 TMF_TATA_bd PF12325.3 AAS52729.1 - 0.018 14.7 115.6 0.019 14.7 10.6 8.1 1 1 7 8 8 8 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 AAS52729.1 - 0.13 12.1 135.9 0.64 9.8 3.2 7.5 1 1 5 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HEAT_EZ PF13513.1 AAS52729.1 - 0.27 11.7 1.9 8.1 7.0 0.0 4.0 4 0 0 4 4 3 0 HEAT-like repeat APG6 PF04111.7 AAS52729.1 - 1.3 7.9 126.3 0.0066 15.5 16.6 6.3 1 1 5 6 6 6 0 Autophagy protein Apg6 Rad52_Rad22 PF04098.10 AAS52730.1 - 1.6e-43 148.0 0.1 2e-43 147.7 0.1 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein IKI3 PF04762.7 AAS52731.2 - 0 1122.4 0.0 0 1122.2 0.0 1.1 1 0 0 1 1 1 1 IKI3 family TPR_8 PF13181.1 AAS52731.2 - 0.06 13.1 5.3 0.25 11.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Vac14_Fig4_bd PF11916.3 AAS52733.2 - 7.7e-74 246.7 4.3 3e-73 244.8 3.0 2.1 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 AAS52733.2 - 1.6e-47 159.8 3.4 4.2e-39 132.8 0.2 4.4 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 AAS52733.2 - 6.3e-15 53.8 2.3 0.00023 20.9 0.0 7.0 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 AAS52733.2 - 9.3e-12 45.0 0.2 0.0066 16.7 0.0 6.2 4 2 0 4 4 4 2 HEAT repeats CLASP_N PF12348.3 AAS52733.2 - 5.6e-08 32.4 3.2 0.0012 18.2 0.2 4.4 3 2 1 4 4 4 2 CLASP N terminal MMS19_C PF12460.3 AAS52733.2 - 6e-06 25.2 18.6 0.024 13.3 1.5 4.9 5 1 0 5 5 5 3 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.1 AAS52733.2 - 3.2e-05 24.2 0.8 0.057 13.9 0.0 5.0 6 0 0 6 6 6 1 HEAT-like repeat Cnd1 PF12717.2 AAS52733.2 - 0.0017 18.2 14.7 1.8 8.3 0.5 5.5 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 AAS52733.2 - 0.01 15.6 0.4 2.9 7.8 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 AAS52733.2 - 0.48 10.0 5.9 1.1 8.9 0.2 3.7 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis zf-C2H2_2 PF12756.2 AAS52734.1 - 5e-28 97.1 6.9 3.3e-26 91.3 1.4 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 AAS52734.1 - 0.034 14.2 1.1 0.034 14.2 0.8 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF488 PF04343.8 AAS52734.1 - 0.063 13.6 0.2 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF488 AKAP95 PF04988.7 AAS52734.1 - 1.5 8.5 6.8 6.1 6.5 0.3 3.1 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) DUF663 PF04950.7 AAS52735.1 - 6e-92 307.7 0.0 8.8e-92 307.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 AAS52735.1 - 1.1e-22 79.2 0.0 2.5e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DUF4055 PF13264.1 AAS52735.1 - 2.4 8.2 4.6 0.59 10.2 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) Ribosomal_S14 PF00253.16 AAS52736.1 - 2.4e-19 68.4 4.1 2.7e-19 68.3 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 AAS52736.1 - 0.036 14.1 1.6 2.4 8.3 0.1 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase CDK5_activator PF03261.10 AAS52736.1 - 0.089 12.1 0.0 0.098 11.9 0.0 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF2296 PF10058.4 AAS52736.1 - 0.21 11.3 2.1 2.5 7.9 0.0 2.1 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Peptidase_M16 PF00675.15 AAS52737.2 - 1.4e-41 141.6 0.3 7.1e-41 139.4 0.1 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AAS52737.2 - 6.7e-32 110.6 1.6 1.3e-17 64.1 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain CorC_HlyC PF03471.12 AAS52737.2 - 0.092 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Transporter associated domain Arm PF00514.18 AAS52739.1 - 0.56 10.1 4.9 3.8 7.4 0.0 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat UQ_con PF00179.21 AAS52740.1 - 9.2e-45 151.5 0.2 1e-44 151.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AAS52740.1 - 5.7e-06 26.1 0.0 6.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AAS52740.1 - 0.38 10.6 2.4 0.62 9.9 1.7 1.8 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.7 AAS52741.1 - 2.1e-66 224.0 4.2 2.1e-66 224.0 2.9 1.7 1 1 1 2 2 2 1 Pex19 protein family Med15 PF09606.5 AAS52741.1 - 0.65 8.1 12.8 0.85 7.7 8.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Rgp1 PF08737.5 AAS52741.1 - 0.83 8.6 4.9 3 6.8 3.3 1.8 1 1 0 1 1 1 0 Rgp1 DUF4208 PF13907.1 AAS52741.1 - 2.4 8.4 6.2 3.8 7.7 0.0 3.5 3 2 1 4 4 4 0 Domain of unknown function (DUF4208) XPC-binding PF09280.6 AAS52741.1 - 3.6 7.1 7.3 5.2 6.6 0.1 3.8 4 0 0 4 4 4 0 XPC-binding domain CFEM PF05730.6 AAS52742.2 - 0.0012 18.5 5.4 0.0029 17.4 3.7 1.7 1 0 0 1 1 1 1 CFEM domain DUF605 PF04652.11 AAS52742.2 - 0.81 9.0 23.1 1.1 8.6 16.0 1.2 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 AAS52742.2 - 6.2 6.2 28.1 7.9 5.8 19.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) FAM196 PF15265.1 AAS52742.2 - 8.8 5.4 15.6 11 5.1 10.8 1.0 1 0 0 1 1 1 0 FAM196 family Arrestin_N PF00339.24 AAS52743.1 - 1e-07 31.8 0.0 1.1e-05 25.3 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain ATP-synt_10 PF05176.9 AAS52744.2 - 1.1e-90 303.3 0.0 1.3e-90 303.0 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Iso_dh PF00180.15 AAS52745.1 - 3.8e-68 229.9 0.0 4.4e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase COX7C PF02935.11 AAS52746.1 - 8.2e-22 76.7 1.6 8.7e-22 76.6 1.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Sec1 PF00995.18 AAS52748.1 - 4.7e-59 200.4 0.0 2.4e-58 198.1 0.0 1.8 1 1 0 1 1 1 1 Sec1 family AAA PF00004.24 AAS52749.2 - 5.8e-87 288.6 0.0 6.9e-42 142.7 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AAS52749.2 - 1.3e-14 53.8 0.0 8.8e-06 24.9 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AAS52749.2 - 1.5e-12 47.7 1.3 4.7e-06 26.7 0.0 4.5 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AAS52749.2 - 1.9e-11 44.3 0.5 1.5e-05 25.0 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 AAS52749.2 - 6.2e-11 42.1 0.3 0.00064 19.4 0.0 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AAS52749.2 - 4.6e-10 39.6 0.0 0.0002 21.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 AAS52749.2 - 2.8e-08 33.7 0.0 0.0025 17.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.13 AAS52749.2 - 2.3e-07 30.6 0.0 6.5e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_33 PF13671.1 AAS52749.2 - 1.1e-06 28.5 0.0 0.00052 19.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AAS52749.2 - 2.5e-06 28.3 0.0 0.08 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 AAS52749.2 - 2.6e-06 27.2 0.0 0.0025 17.5 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_19 PF13245.1 AAS52749.2 - 3.1e-06 26.8 0.8 0.0037 16.9 0.0 4.0 4 0 0 4 4 3 1 Part of AAA domain NACHT PF05729.7 AAS52749.2 - 1.6e-05 24.6 0.4 0.067 12.8 0.0 4.0 4 0 0 4 4 4 1 NACHT domain TIP49 PF06068.8 AAS52749.2 - 1.8e-05 23.6 0.0 0.028 13.1 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus Arch_ATPase PF01637.13 AAS52749.2 - 1.8e-05 24.5 0.0 0.38 10.4 0.0 3.5 2 2 1 3 3 3 2 Archaeal ATPase AAA_28 PF13521.1 AAS52749.2 - 3e-05 24.0 0.0 0.21 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 AAS52749.2 - 4.1e-05 22.8 0.5 0.11 11.5 0.0 2.8 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 AAS52749.2 - 5.2e-05 22.1 0.0 0.05 12.2 0.0 2.5 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 AAS52749.2 - 9.8e-05 22.4 0.0 0.85 9.8 0.0 2.9 2 1 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.7 AAS52749.2 - 0.00012 21.1 0.0 0.049 12.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 AAS52749.2 - 0.00014 21.3 8.6 0.28 10.5 0.1 4.4 2 2 1 4 4 4 2 AAA domain AAA_18 PF13238.1 AAS52749.2 - 0.00019 21.7 0.0 0.33 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 AAS52749.2 - 0.00021 20.8 0.0 0.4 10.2 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 AAS52749.2 - 0.00033 20.7 0.0 0.43 10.6 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 AAS52749.2 - 0.00043 19.7 0.0 0.67 9.3 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.22 AAS52749.2 - 0.0015 18.8 0.0 0.025 14.8 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_11 PF13086.1 AAS52749.2 - 0.0035 16.9 0.0 1.4 8.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain AFG1_ATPase PF03969.11 AAS52749.2 - 0.012 14.3 0.0 0.077 11.7 0.0 2.2 2 1 0 2 2 2 0 AFG1-like ATPase DUF815 PF05673.8 AAS52749.2 - 0.026 13.4 0.0 2 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 AAS52749.2 - 0.029 13.8 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 AAS52749.2 - 0.037 13.6 0.2 10 5.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 AAS52749.2 - 0.043 12.9 0.5 13 4.8 0.0 3.5 3 1 1 4 4 4 0 KaiC Sigma54_activat PF00158.21 AAS52749.2 - 0.048 13.1 0.0 14 5.0 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain cobW PF02492.14 AAS52749.2 - 0.052 12.9 0.1 0.2 11.0 0.0 2.0 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain GIDA_assoc_3 PF13932.1 AAS52749.2 - 0.077 13.0 0.1 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 GidA associated domain 3 NTPase_1 PF03266.10 AAS52749.2 - 0.079 12.6 0.8 14 5.3 0.0 3.5 2 2 2 4 4 4 0 NTPase UPF0079 PF02367.12 AAS52749.2 - 0.11 12.0 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 AAS52749.2 - 0.12 11.8 0.0 0.8 9.1 0.0 2.1 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Phage-tail_2 PF09096.5 AAS52750.1 - 0.14 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Baseplate structural protein, domain 2 DSHCT PF08148.7 AAS52751.2 - 4.1e-59 198.8 0.2 8.3e-59 197.8 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 AAS52751.2 - 9.6e-23 80.5 0.1 2.6e-22 79.1 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS52751.2 - 4.4e-07 29.6 0.0 1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 AAS52751.2 - 6.6e-05 22.1 0.1 0.00019 20.6 0.0 1.7 1 1 0 1 1 1 1 rRNA-processing arch domain ResIII PF04851.10 AAS52751.2 - 0.0028 17.5 0.1 0.011 15.6 0.1 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Bromodomain PF00439.20 AAS52752.2 - 1.2e-41 140.5 0.2 8.4e-21 73.6 0.0 2.5 2 0 0 2 2 2 2 Bromodomain Bap31 PF05529.7 AAS52753.1 - 5.6e-43 146.6 10.2 6.6e-41 139.8 7.1 2.0 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF2189 PF09955.4 AAS52753.1 - 0.045 13.6 0.3 0.045 13.6 0.2 1.9 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2189) DivIC PF04977.10 AAS52753.1 - 0.1 12.0 0.1 0.54 9.7 0.0 2.0 2 0 0 2 2 2 0 Septum formation initiator Dus PF01207.12 AAS52754.1 - 1.1e-47 162.3 0.0 7.4e-46 156.3 0.0 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 AAS52754.1 - 1.5e-05 24.5 10.6 0.0011 18.5 0.2 3.4 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_4 PF13894.1 AAS52755.2 - 3.1e-05 23.9 10.9 0.047 14.0 0.3 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AAS52755.2 - 0.00034 20.6 5.7 0.13 12.4 0.0 3.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 AAS52755.2 - 0.0051 17.0 17.3 0.082 13.2 0.8 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type PBP1_TM PF14812.1 AAS52755.2 - 0.0054 17.0 6.2 0.015 15.5 4.3 1.7 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 AAS52755.2 - 0.02 14.3 1.3 0.034 13.6 0.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin zf-H2C2_2 PF13465.1 AAS52755.2 - 0.038 14.2 1.1 0.038 14.2 0.8 3.9 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 AAS52755.2 - 0.25 11.3 4.5 2.8 7.9 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4611 PF15387.1 AAS52755.2 - 0.96 9.6 6.6 2.1 8.5 4.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF1765 PF08578.5 AAS52757.2 - 4.9e-29 100.9 0.3 4.9e-29 100.9 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) BRE1 PF08647.6 AAS52758.1 - 3.1e-31 107.2 18.1 3.1e-31 107.2 12.6 5.4 5 1 0 5 5 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.1 AAS52758.1 - 7.6e-07 28.6 10.6 1.3e-06 27.9 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS52758.1 - 9.5e-07 28.7 12.7 1.6e-06 27.9 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AAS52758.1 - 9.5e-06 25.1 12.7 1.7e-05 24.3 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AAS52758.1 - 2.6e-05 23.8 12.7 4.5e-05 23.1 8.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 AAS52758.1 - 0.00071 19.3 11.0 0.0013 18.5 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C2H2 PF00096.21 AAS52758.1 - 0.011 16.0 0.1 0.011 16.0 0.1 2.7 3 0 0 3 3 2 0 Zinc finger, C2H2 type DUF904 PF06005.7 AAS52758.1 - 0.014 15.6 1.5 0.014 15.6 1.1 7.7 3 1 2 5 5 4 0 Protein of unknown function (DUF904) zf-RING_UBOX PF13445.1 AAS52758.1 - 0.027 14.2 7.4 0.079 12.6 5.1 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C2H2_jaz PF12171.3 AAS52758.1 - 0.036 14.2 0.8 0.7 10.1 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Prok-RING_4 PF14447.1 AAS52758.1 - 0.057 12.9 5.5 0.13 11.8 3.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 AAS52758.1 - 0.082 12.6 4.9 0.18 11.6 3.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 AAS52758.1 - 0.51 9.9 10.1 0.98 9.0 7.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 AAS52758.1 - 0.82 9.6 9.5 1.6 8.6 6.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING LPP PF04728.8 AAS52758.1 - 1.1 9.1 6.7 2.4 8.0 0.1 4.0 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Dus PF01207.12 AAS52759.1 - 9.3e-79 264.4 0.0 1.2e-78 264.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PEP_mutase PF13714.1 AAS52759.1 - 0.017 14.3 0.3 0.09 11.9 0.0 2.1 1 1 1 2 2 2 0 Phosphoenolpyruvate phosphomutase TMP-TENI PF02581.12 AAS52759.1 - 0.045 12.8 0.1 0.077 12.1 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Resolvase PF00239.16 AAS52759.1 - 0.062 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Resolvase, N terminal domain Ribosomal_L31e PF01198.14 AAS52760.2 - 1.4e-37 127.1 1.7 1.7e-37 126.9 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Rxt3 PF08642.5 AAS52761.1 - 4.3e-33 113.9 0.0 7.1e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 SBP_bac_10 PF07596.6 AAS52761.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1559) DUF4050 PF13259.1 AAS52762.1 - 2.2e-22 79.2 0.3 3.4e-22 78.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) GCN5L1 PF06320.8 AAS52763.1 - 0.058 13.2 0.2 0.079 12.7 0.2 1.4 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Vps39_1 PF10366.4 AAS52764.1 - 1.2e-34 118.5 4.0 2.2e-34 117.7 1.2 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 AAS52764.1 - 9.3e-15 54.7 0.0 2.4e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 AAS52764.1 - 0.0025 17.4 20.0 0.004 16.7 1.6 3.9 4 1 0 4 4 4 2 Region in Clathrin and VPS Rad50_zn_hook PF04423.9 AAS52764.1 - 0.052 13.0 0.5 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif Utp21 PF04192.7 AAS52765.2 - 5e-84 281.1 2.4 7.9e-84 280.4 1.7 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 AAS52765.2 - 1.2e-22 78.9 11.7 2.4e-08 33.5 0.3 9.9 11 1 0 11 11 11 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 AAS52765.2 - 1.2e-05 23.7 0.0 0.0002 19.7 0.0 2.3 2 0 0 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.6 AAS52765.2 - 0.0013 18.4 0.7 1.6 8.3 0.0 4.0 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A CPSF_A PF03178.10 AAS52765.2 - 0.011 14.8 0.1 0.15 11.1 0.0 2.7 3 0 0 3 3 3 0 CPSF A subunit region His_Phos_2 PF00328.17 AAS52766.1 - 8.1e-135 449.6 0.3 1.4e-134 448.8 0.2 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 AAS52766.1 - 3.7e-08 33.0 0.0 8.1e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF2404 PF10296.4 AAS52766.1 - 0.049 13.7 0.0 0.62 10.2 0.0 2.7 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) Pribosyl_synth PF14572.1 AAS52767.1 - 6.3e-40 136.8 2.9 3e-31 108.6 0.1 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 AAS52767.1 - 8.5e-39 131.8 0.0 7.2e-38 128.8 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 AAS52767.1 - 3.5e-08 33.2 0.2 4.4e-07 29.6 0.1 2.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain SRR1 PF07985.7 AAS52768.1 - 4.8e-18 64.8 0.0 8.1e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 SRR1 Acyl_transf_1 PF00698.16 AAS52769.2 - 5.8e-95 318.2 0.0 1.5e-93 313.6 0.0 3.0 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 AAS52769.2 - 1.5e-37 127.7 0.0 3e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 AAS52769.2 - 3.3e-30 103.6 0.0 9e-30 102.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 AAS52769.2 - 2.8e-14 53.0 0.0 2.2e-13 50.1 0.0 2.5 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase Lipase_3 PF01764.20 AAS52769.2 - 0.044 13.3 0.1 0.81 9.3 0.0 2.6 2 0 0 2 2 2 0 Lipase (class 3) Voldacs PF03517.8 AAS52770.2 - 1.7e-13 50.5 0.0 3.4e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling Orn_Arg_deC_N PF02784.11 AAS52771.2 - 1.7e-75 253.4 0.0 2.4e-75 252.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 AAS52771.2 - 5.3e-29 100.2 0.1 1e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.15 AAS52771.2 - 0.0034 16.9 0.1 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain GATA PF00320.22 AAS52772.2 - 3.8e-08 32.5 12.9 3.8e-08 32.5 8.9 1.8 2 0 0 2 2 2 1 GATA zinc finger Mtr2 PF10429.4 AAS52773.1 - 2.7e-71 238.6 0.0 3e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 SnoaL_4 PF13577.1 AAS52773.1 - 0.017 15.0 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.1 AAS52773.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) SUR7 PF06687.7 AAS52774.1 - 2.5e-11 43.5 0.0 8.2e-11 41.8 0.0 1.8 1 1 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 AAS52774.1 - 0.0051 16.7 4.7 0.0051 16.7 3.3 2.1 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 HCR PF07111.7 AAS52774.1 - 0.023 12.7 0.3 0.041 11.9 0.2 1.3 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) ABC_membrane_2 PF06472.10 AAS52775.1 - 2.8e-62 210.3 5.4 9.3e-41 139.7 0.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.22 AAS52775.1 - 2.1e-16 60.4 0.0 4.6e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AAS52775.1 - 7.6e-07 29.3 1.7 2.2e-06 27.8 0.0 2.6 2 1 1 3 3 3 1 AAA domain Lysis_S PF04971.7 AAS52775.1 - 0.00051 19.6 0.3 0.49 10.1 0.0 2.5 2 0 0 2 2 2 2 Lysis protein S Rad17 PF03215.10 AAS52775.1 - 0.011 14.5 0.0 0.02 13.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 AAS52775.1 - 0.015 14.8 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 AAS52775.1 - 0.02 14.0 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SMC_N PF02463.14 AAS52775.1 - 0.024 13.8 0.3 0.068 12.3 0.2 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AAS52775.1 - 0.044 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 AAS52775.1 - 0.083 13.2 6.0 0.56 10.4 4.1 2.3 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 AAS52775.1 - 0.13 11.4 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI EAP30 PF04157.11 AAS52776.1 - 1.4e-39 135.5 0.3 1.7e-38 132.0 0.2 2.3 1 1 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 AAS52776.1 - 2.8e-31 107.1 0.1 5.5e-31 106.2 0.1 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 AAS52776.1 - 0.0066 15.5 2.5 0.0066 15.5 1.7 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 AAS52776.1 - 0.015 14.8 10.2 0.042 13.4 0.1 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger bPH_3 PF14470.1 AAS52776.1 - 0.023 14.9 0.2 0.051 13.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial PH domain DZR PF12773.2 AAS52776.1 - 0.036 13.9 9.9 0.033 14.0 3.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 AAS52776.1 - 0.051 12.7 6.8 0.037 13.2 1.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain GRAM PF02893.15 AAS52776.1 - 0.067 12.7 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 GRAM domain DUF2471 PF10616.4 AAS52776.1 - 0.094 12.9 0.0 0.67 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2471) Mo25 PF08569.6 AAS52777.1 - 6.4e-124 413.3 5.5 7.2e-124 413.1 3.8 1.0 1 0 0 1 1 1 1 Mo25-like OB_NTP_bind PF07717.11 AAS52778.2 - 2.3e-13 49.9 0.0 6.2e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 AAS52778.2 - 1.6e-12 47.2 1.9 3.3e-11 42.9 1.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS52778.2 - 6.3e-12 45.1 0.0 1.8e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 AAS52778.2 - 9.4e-12 44.8 0.0 2.6e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) RWD PF05773.17 AAS52778.2 - 2.5e-11 43.4 0.5 7e-11 42.0 0.0 2.1 2 0 0 2 2 1 1 RWD domain AAA_19 PF13245.1 AAS52778.2 - 6.9e-05 22.5 0.1 0.00018 21.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 AAS52778.2 - 0.00079 18.9 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain UBA PF00627.26 AAS52778.2 - 0.00094 18.9 0.0 0.0022 17.7 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Zot PF05707.7 AAS52778.2 - 0.0021 17.5 0.1 0.0052 16.2 0.1 1.7 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 AAS52778.2 - 0.0045 17.1 0.1 0.015 15.4 0.1 1.9 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 AAS52778.2 - 0.0062 15.7 0.1 0.036 13.3 0.1 2.2 2 1 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 AAS52778.2 - 0.0079 15.1 0.1 0.015 14.2 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 AAS52778.2 - 0.01 14.9 0.6 0.035 13.2 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.1 AAS52778.2 - 0.023 15.0 2.1 0.061 13.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 AAS52778.2 - 0.069 12.6 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family CDC73 PF05179.9 AAS52779.1 - 5.9e-64 216.0 0.7 7.3e-64 215.7 0.5 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family PSRP-3_Ycf65 PF04839.8 AAS52779.1 - 0.75 9.8 4.6 2.6 8.1 0.0 3.0 3 0 0 3 3 3 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) EF-hand_1 PF00036.27 AAS52780.1 - 1.1e-25 86.8 11.7 3.9e-06 25.7 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 AAS52780.1 - 5.6e-21 72.5 3.8 0.00013 21.5 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 AAS52780.1 - 7.2e-21 74.1 2.9 3.7e-11 43.0 0.7 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 AAS52780.1 - 1e-16 59.3 16.0 3.8e-05 22.8 0.1 4.7 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.1 AAS52780.1 - 9.3e-14 50.7 15.0 0.00049 19.6 0.4 4.4 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 AAS52780.1 - 6.6e-07 29.3 0.0 0.0041 17.1 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 AAS52780.1 - 1.2e-06 28.2 9.5 0.012 15.3 0.2 4.0 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 AAS52780.1 - 0.00064 19.5 0.1 0.47 10.4 0.0 2.7 2 1 1 3 3 3 2 EF-hand domain Diphthamide_syn PF01866.12 AAS52781.1 - 3.8e-41 141.3 0.0 1.3e-19 70.5 0.0 2.3 2 0 0 2 2 2 2 Putative diphthamide synthesis protein Amidohydro_4 PF13147.1 AAS52782.2 - 3.3e-13 50.2 0.4 4.4e-13 49.9 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 AAS52782.2 - 7.3e-08 32.2 0.1 1.8e-07 31.0 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase Proteasom_Rpn13 PF04683.8 AAS52784.1 - 2.8e-24 84.9 0.0 3.7e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor CinA PF02464.12 AAS52785.1 - 4.8e-32 110.5 0.1 5.5e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 Competence-damaged protein Ded_cyto PF06920.8 AAS52786.1 - 9.2e-20 70.6 0.0 1.8e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_6 PF12913.2 AAS52786.1 - 0.018 14.2 0.1 1.7 7.8 0.0 2.9 3 0 0 3 3 3 0 SH3 domain of the SH3b1 type PP-binding PF00550.20 AAS52787.1 - 2e-11 43.9 0.3 2.7e-11 43.5 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 AAS52787.1 - 2.5e-07 30.6 1.2 3.1e-07 30.3 0.8 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 AAS52787.1 - 0.00014 21.8 0.2 0.00022 21.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) tRNA-synt_2c PF01411.14 AAS52787.1 - 0.11 10.7 0.0 0.13 10.5 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class II (A) LRR_4 PF12799.2 AAS52788.1 - 3.8e-42 141.2 37.0 2e-08 33.6 0.4 7.2 3 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AAS52788.1 - 9.9e-32 108.4 43.3 1.8e-07 30.7 2.6 6.0 2 1 7 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 AAS52788.1 - 9.7e-17 58.4 28.1 0.079 13.0 0.1 10.8 11 1 0 11 11 11 6 Leucine Rich Repeat LRR_6 PF13516.1 AAS52788.1 - 2.2e-12 45.6 20.1 0.19 11.8 0.5 10.0 7 3 1 8 8 8 3 Leucine Rich repeat LRR_9 PF14580.1 AAS52788.1 - 5.4e-12 45.6 13.0 8.1e-08 32.0 1.9 3.1 1 1 2 3 3 3 2 Leucine-rich repeat LRR_7 PF13504.1 AAS52788.1 - 3.9e-11 41.2 15.2 2.9 8.4 0.0 10.0 10 0 0 10 10 10 3 Leucine rich repeat LRR_2 PF07723.8 AAS52788.1 - 0.12 12.9 2.4 85 3.8 0.3 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat Glyco_hydro_4 PF02056.11 AAS52788.1 - 0.2 10.9 0.9 0.62 9.3 0.2 2.0 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase DUF3744 PF12558.3 AAS52788.1 - 1.5 9.2 13.7 2.6 8.5 1.0 4.6 3 2 1 4 4 4 0 ATP-binding cassette cobalt transporter tRNA-synt_2b PF00587.20 AAS52789.1 - 5.8e-48 162.7 0.0 8.1e-48 162.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AAS52789.1 - 6e-17 61.3 0.0 1.2e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain APG17 PF04108.7 AAS52790.1 - 1.1e-118 396.6 14.6 1.2e-118 396.4 10.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Herpes_U30 PF04523.8 AAS52790.1 - 0.0019 15.7 0.7 0.0031 15.0 0.5 1.3 1 0 0 1 1 1 1 Herpes virus tegument protein U30 Baculo_PEP_C PF04513.7 AAS52790.1 - 0.0044 16.8 5.3 2.4 7.9 0.1 4.1 4 0 0 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus YojJ PF10372.4 AAS52790.1 - 0.039 13.8 0.2 0.68 9.8 0.0 2.9 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DASH_Duo1 PF08651.5 AAS52790.1 - 0.048 13.2 5.0 3 7.4 0.0 4.0 3 1 1 4 4 4 0 DASH complex subunit Duo1 FTO_CTD PF12934.2 AAS52790.1 - 0.065 12.8 1.6 0.19 11.3 0.0 2.5 3 1 0 3 3 3 0 FTO C-terminal domain WXG100 PF06013.7 AAS52790.1 - 2.1 8.3 8.9 22 5.1 0.0 4.5 4 1 1 5 5 5 0 Proteins of 100 residues with WXG Syntaxin PF00804.20 AAS52790.1 - 3.2 7.9 16.9 8.8 6.5 0.2 4.1 2 1 0 2 2 2 0 Syntaxin Bacillus_HBL PF05791.6 AAS52790.1 - 5.3 6.3 12.0 0.46 9.8 0.5 3.5 1 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) G-patch PF01585.18 AAS52791.1 - 8e-15 54.3 5.0 1.5e-14 53.4 3.5 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 AAS52791.1 - 8.5e-09 35.1 0.7 1.7e-08 34.1 0.5 1.4 1 0 0 1 1 1 1 DExH-box splicing factor binding site FUSC PF04632.7 AAS52791.1 - 0.053 11.9 0.7 0.095 11.1 0.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family CHCH PF06747.8 AAS52792.1 - 3.9e-08 33.0 3.8 6.8e-08 32.2 2.6 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 AAS52792.1 - 0.0095 16.0 2.5 0.026 14.6 1.7 1.7 1 0 0 1 1 1 1 GCK domain Synaptobrevin PF00957.16 AAS52793.1 - 3.3e-15 55.4 0.7 5.4e-15 54.7 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 AAS52793.1 - 1.6e-14 53.1 0.0 2.9e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain CNH PF00780.17 AAS52794.2 - 1.4e-18 67.3 0.5 4.6e-18 65.6 0.3 1.8 1 1 0 1 1 1 1 CNH domain PH PF00169.24 AAS52794.2 - 1e-10 41.7 0.1 4e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 PH domain RhoGEF PF00621.15 AAS52794.2 - 6.8e-09 35.8 0.0 1.8e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 AAS52794.2 - 4.3e-06 26.7 0.1 8.9e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain adh_short PF00106.20 AAS52795.1 - 2.2e-21 76.4 0.3 3.7e-21 75.7 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AAS52795.1 - 2e-09 37.3 0.4 8.8e-09 35.2 0.3 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 AAS52795.1 - 0.00019 20.9 0.2 0.0005 19.5 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 AAS52795.1 - 0.00024 20.9 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 AAS52795.1 - 0.14 11.0 0.2 2.7 6.8 0.2 2.2 1 1 0 1 1 1 0 Male sterility protein SPC25 PF06703.6 AAS52796.1 - 2.8e-34 118.0 0.0 3.2e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) zf-C3HC4 PF00097.20 AAS52797.2 - 1.2e-06 28.0 0.3 2.9e-06 26.8 0.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS52797.2 - 8.6e-06 25.6 4.6 2e-05 24.5 3.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AAS52797.2 - 9.3e-06 25.2 2.2 2e-05 24.1 1.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 AAS52797.2 - 1e-05 25.2 3.7 2.2e-05 24.1 2.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AAS52797.2 - 1.5e-05 24.5 3.7 3.2e-05 23.5 2.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AAS52797.2 - 0.00049 19.9 1.2 0.00049 19.9 0.8 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 AAS52797.2 - 0.00052 19.6 2.2 0.0012 18.5 1.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 AAS52797.2 - 9.6 5.8 7.9 45 3.6 5.5 2.1 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger DUF1900 PF08954.6 AAS52798.1 - 5.9e-51 171.5 0.0 1.3e-50 170.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 AAS52798.1 - 3.5e-31 106.6 0.2 5.9e-31 105.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 AAS52798.1 - 2e-25 87.6 2.3 9.1e-07 28.5 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 AAS52798.1 - 2.6e-07 29.1 0.1 0.00087 17.5 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF148 PF02520.12 AAS52798.1 - 0.049 13.4 4.2 0.079 12.7 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 BLOC1_2 PF10046.4 AAS52798.1 - 0.07 13.2 0.7 0.14 12.2 0.2 1.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HSCB_C PF07743.8 AAS52798.1 - 0.33 11.4 3.2 0.77 10.2 2.3 1.6 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain TMF_DNA_bd PF12329.3 AAS52798.1 - 1.3 8.8 7.2 1.3 8.9 2.1 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding SEN1_N PF12726.2 AAS52799.2 - 2.7e-218 726.6 8.8 3.4e-218 726.2 6.1 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 AAS52799.2 - 1.4e-67 227.7 0.4 1.4e-67 227.7 0.3 1.8 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 AAS52799.2 - 1.8e-64 216.7 1.1 7.1e-63 211.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 AAS52799.2 - 2.6e-09 36.7 0.0 7.1e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 AAS52799.2 - 3e-07 30.2 0.0 0.00041 19.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 AAS52799.2 - 6.1e-05 22.6 0.0 0.22 10.9 0.0 4.1 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 AAS52799.2 - 0.0048 17.0 0.0 0.033 14.3 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Neuropeptide_S PF14993.1 AAS52799.2 - 0.029 14.0 0.0 0.077 12.6 0.0 1.7 1 0 0 1 1 1 0 Neuropeptide S precursor protein Borrelia_lipo_1 PF05714.6 AAS52800.1 - 0.0028 16.7 0.0 0.39 9.7 0.0 2.3 2 0 0 2 2 2 2 Borrelia burgdorferi virulent strain associated lipoprotein TBCA PF02970.11 AAS52800.1 - 0.031 14.3 1.4 0.031 14.3 0.9 3.1 3 0 0 3 3 3 0 Tubulin binding cofactor A DUF4570 PF15134.1 AAS52800.1 - 1.7 8.4 8.1 9 6.1 1.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) DUF342 PF03961.8 AAS52800.1 - 3.5 5.9 5.1 1.3 7.3 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF342) IMPDH PF00478.20 AAS52801.2 - 7.9e-143 475.5 3.1 9.4e-143 475.3 2.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 AAS52801.2 - 7e-19 67.3 0.0 2.4e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 AAS52801.2 - 1.5e-07 30.6 2.0 4.2e-07 29.1 1.4 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 AAS52801.2 - 2.9e-06 26.6 8.6 0.004 16.3 4.1 2.4 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 AAS52801.2 - 3.5e-05 23.1 1.8 0.0021 17.3 0.2 2.5 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 AAS52801.2 - 0.0056 15.7 2.2 0.0067 15.5 0.4 2.0 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.14 AAS52801.2 - 0.013 14.7 1.0 0.044 12.9 0.1 2.2 2 0 0 2 2 2 0 KDPG and KHG aldolase Metallophos PF00149.23 AAS52802.1 - 1.6e-43 148.4 0.2 2.5e-43 147.8 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WGG PF10273.4 AAS52803.1 - 7.9e-30 102.7 0.1 1.3e-29 102.0 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF4375 PF14300.1 AAS52803.1 - 0.033 14.1 0.2 0.061 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) DUF3245 PF11595.3 AAS52803.1 - 0.11 12.7 3.3 0.18 12.0 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) NOA36 PF06524.7 AAS52803.1 - 1 8.5 4.8 1.4 8.1 3.4 1.1 1 0 0 1 1 1 0 NOA36 protein Hid1 PF12722.2 AAS52804.2 - 6.7e-212 705.7 3.4 8.1e-212 705.4 2.3 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 AAS52804.2 - 8e-16 57.3 10.0 7.2e-13 47.5 6.0 3.0 2 1 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein DUF2192 PF09958.4 AAS52804.2 - 0.18 10.9 0.1 0.37 9.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2192) MIP-T3 PF10243.4 AAS52804.2 - 2.5 6.4 2.2 5 5.4 1.5 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RNR_inhib PF08591.5 AAS52805.1 - 7.5e-20 71.6 0.0 1.2e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor Aminotran_3 PF00202.16 AAS52806.1 - 1e-106 356.6 0.0 1.2e-106 356.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 AAS52806.1 - 5.8e-05 22.3 0.0 0.00013 21.2 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase cNMP_binding PF00027.24 AAS52807.1 - 4.8e-38 128.8 0.2 1.5e-16 59.9 0.0 4.2 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.17 AAS52807.1 - 4.6e-20 72.4 1.3 2.7e-12 47.0 0.8 2.7 2 0 0 2 2 2 2 Patatin-like phospholipase LSM PF01423.17 AAS52808.1 - 6.9e-18 63.9 0.0 8.4e-18 63.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AAS52808.1 - 0.056 13.3 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain SH3_9 PF14604.1 AAS52808.1 - 0.073 12.6 0.0 4.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Variant SH3 domain MRP-L47 PF06984.8 AAS52809.2 - 7.1e-25 86.7 0.6 1.5e-24 85.7 0.4 1.6 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) OGG_N PF07934.7 AAS52810.1 - 2e-22 79.3 0.2 4.5e-22 78.2 0.1 1.7 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 AAS52810.1 - 6.5e-14 52.1 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 AAS52810.1 - 0.0097 15.5 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif PIF1 PF05970.9 AAS52811.1 - 4.8e-73 246.2 0.7 3.4e-57 194.0 0.2 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 AAS52811.1 - 2.2e-12 46.9 0.0 4.7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AAS52811.1 - 3.7e-06 27.1 0.3 1.1e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 AAS52811.1 - 2.7e-05 23.8 0.5 0.013 15.0 0.1 2.8 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.9 AAS52811.1 - 0.00016 19.6 0.1 0.0015 16.3 0.0 2.0 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 AAS52811.1 - 0.00018 21.6 0.2 0.0067 16.5 0.0 3.2 3 1 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 AAS52811.1 - 0.0057 16.6 0.3 0.023 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 AAS52811.1 - 0.01 14.8 1.3 0.03 13.3 0.2 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 AAS52811.1 - 0.018 14.6 0.0 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 AAS52811.1 - 0.023 13.6 0.0 0.045 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 AAS52811.1 - 0.025 14.7 0.2 0.086 13.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 AAS52811.1 - 0.026 13.7 0.0 0.063 12.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Helicase_RecD PF05127.9 AAS52811.1 - 0.036 13.7 0.3 0.17 11.4 0.1 2.3 2 1 0 2 2 2 0 Helicase AAA_14 PF13173.1 AAS52811.1 - 0.036 13.9 0.1 0.26 11.2 0.0 2.5 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 AAS52811.1 - 0.071 12.6 0.1 3 7.2 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.17 AAS52811.1 - 0.072 13.2 0.0 0.22 11.7 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 AAS52811.1 - 0.12 12.1 0.7 0.27 11.0 0.5 1.5 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 AAS52811.1 - 0.16 11.6 2.6 0.8 9.3 0.6 2.9 2 1 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 AAS52811.1 - 0.2 11.9 1.5 0.97 9.7 0.3 2.7 1 1 1 2 2 2 0 ABC transporter Sec39 PF08314.6 AAS52812.1 - 2.9e-169 564.3 0.6 3.3e-169 564.1 0.4 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 THOC7 PF05615.8 AAS52813.1 - 1.8e-23 83.3 6.4 1.8e-23 83.3 4.4 2.2 2 0 0 2 2 2 1 Tho complex subunit 7 Herpes_UL6 PF01763.11 AAS52813.1 - 1 7.4 6.5 0.078 11.1 0.6 1.8 2 0 0 2 2 2 0 Herpesvirus UL6 like DUF4618 PF15397.1 AAS52813.1 - 7.7 5.7 18.9 0.23 10.7 3.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Ribosomal_S3Ae PF01015.13 AAS52814.1 - 3.5e-80 267.9 7.3 4.1e-80 267.7 5.1 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 AAS52814.1 - 0.04 13.2 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Ribosomal_L22 PF00237.14 AAS52814.1 - 0.13 12.2 1.6 3.4 7.6 0.9 2.5 1 1 0 1 1 1 0 Ribosomal protein L22p/L17e Ras PF00071.17 AAS52815.1 - 1.8e-29 102.2 0.1 2.2e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS52815.1 - 4e-19 69.2 0.0 1.8e-18 67.1 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AAS52815.1 - 5.1e-05 22.5 0.1 6.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AAS52815.1 - 0.0002 20.5 0.1 0.00024 20.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AAS52815.1 - 0.0037 17.1 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 AAS52815.1 - 0.067 12.4 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 AAS52815.1 - 0.098 12.1 0.2 0.42 10.0 0.2 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 AAS52815.1 - 0.16 10.6 0.0 0.56 8.8 0.0 1.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA PF00004.24 AAS52816.2 - 4.5e-19 68.9 0.0 1.2e-18 67.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AAS52816.2 - 9.4e-08 32.2 0.0 1.4e-05 25.2 0.0 2.7 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.13 AAS52816.2 - 5e-07 29.4 0.2 1.4e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 BAH domain Arch_ATPase PF01637.13 AAS52816.2 - 7e-07 29.1 0.1 7e-07 29.1 0.1 3.2 3 1 0 3 3 3 1 Archaeal ATPase AAA_22 PF13401.1 AAS52816.2 - 1.4e-06 28.5 0.1 6.7e-06 26.2 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 AAS52816.2 - 0.0013 19.5 0.0 0.0093 16.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 AAS52816.2 - 0.0014 18.9 0.2 0.011 15.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 AAS52816.2 - 0.008 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 AAS52816.2 - 0.026 14.1 0.1 0.063 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AAS52816.2 - 0.061 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Claudin_3 PF06653.6 AAS52817.2 - 0.1 12.2 7.6 0.039 13.6 3.3 1.6 2 0 0 2 2 2 0 Tight junction protein, Claudin-like GpcrRhopsn4 PF10192.4 AAS52818.1 - 0.023 13.8 7.1 0.062 12.4 0.9 3.0 3 0 0 3 3 3 0 Rhodopsin-like GPCR transmembrane domain COPIIcoated_ERV PF07970.7 AAS52819.1 - 1.3e-30 106.7 0.1 1.8e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 AAS52819.1 - 8.6e-19 67.3 0.0 1.8e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2660 PF10859.3 AAS52820.1 - 0.014 15.5 0.2 0.026 14.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) DUF600 PF04634.7 AAS52820.1 - 0.015 15.3 0.6 0.019 15.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF600 DUF4335 PF14233.1 AAS52820.1 - 0.086 12.3 0.1 0.098 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) DUF4546 PF15079.1 AAS52820.1 - 0.088 11.9 0.5 0.097 11.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) SSrecog PF03531.9 AAS52821.1 - 1.9e-72 243.2 2.2 6.1e-72 241.5 0.8 2.4 2 1 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 AAS52821.1 - 7.8e-29 99.5 0.1 3.8e-26 90.9 0.1 3.4 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Dak1 PF02733.12 AAS52822.2 - 2e-129 430.8 0.9 2.7e-129 430.4 0.6 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 AAS52822.2 - 5.6e-48 162.8 1.0 9.2e-48 162.2 0.7 1.3 1 0 0 1 1 1 1 DAK2 domain SH3_9 PF14604.1 AAS52823.1 - 4.9e-15 54.8 0.1 8.7e-15 54.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 AAS52823.1 - 4.2e-14 52.6 0.0 9.1e-14 51.5 0.0 1.5 1 1 0 1 1 1 1 BAR domain SH3_1 PF00018.23 AAS52823.1 - 1.1e-13 50.3 0.1 2.1e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AAS52823.1 - 9.1e-13 47.4 0.0 2.1e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF948 PF06103.6 AAS52823.1 - 0.53 10.1 3.7 5.1 7.0 0.1 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Zn_clus PF00172.13 AAS52824.2 - 1.2e-07 31.4 7.3 2.8e-07 30.3 5.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_binding_2 PF13380.1 AAS52825.1 - 1e-20 74.0 0.0 1.2e-20 73.7 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain Hexokinase_1 PF00349.16 AAS52826.1 - 5.6e-07 29.0 0.1 9.1e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Hexokinase StbA PF06406.6 AAS52826.1 - 0.01 14.8 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 StbA protein Hexokinase_2 PF03727.11 AAS52826.1 - 0.017 14.3 0.0 1.1 8.4 0.0 2.3 1 1 0 2 2 2 0 Hexokinase Cyt-b5 PF00173.23 AAS52827.1 - 2.5e-08 33.5 0.0 3.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain cNMP_binding PF00027.24 AAS52828.1 - 7e-32 109.1 0.0 2.3e-15 56.1 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain F-box-like PF12937.2 AAS52828.1 - 5.2e-08 32.4 0.7 1.4e-07 31.0 0.5 1.9 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 AAS52828.1 - 3.6e-06 26.2 19.9 0.57 10.4 0.3 9.6 9 1 0 9 9 9 2 Leucine Rich Repeat F-box PF00646.28 AAS52828.1 - 7e-06 25.5 1.7 7e-06 25.5 1.1 2.9 4 0 0 4 4 4 1 F-box domain LRR_6 PF13516.1 AAS52828.1 - 8e-06 25.4 14.9 0.93 9.7 0.2 7.7 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.2 AAS52828.1 - 0.011 15.3 11.2 0.077 12.6 0.7 5.5 4 1 4 8 8 8 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 AAS52828.1 - 0.13 12.5 15.9 4.4 7.9 0.4 7.1 8 0 0 8 8 8 0 Leucine rich repeat vATP-synt_AC39 PF01992.11 AAS52829.2 - 6.7e-86 288.4 0.1 7.7e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit 5-FTHF_cyc-lig PF01812.15 AAS52829.2 - 0.11 12.2 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family Dor1 PF04124.7 AAS52830.2 - 7.4e-18 64.1 0.0 1.1e-16 60.2 0.0 2.5 1 1 0 1 1 1 1 Dor1-like family C2 PF00168.25 AAS52831.1 - 1.7e-43 146.3 3.5 7.7e-17 60.9 0.1 5.6 5 0 0 5 5 5 5 C2 domain NT-C2 PF10358.4 AAS52831.1 - 0.004 16.6 0.3 0.053 13.0 0.0 3.0 4 0 0 4 4 4 1 N-terminal C2 in EEIG1 and EHBP1 proteins Ribosomal_L6e PF01159.14 AAS52832.1 - 1.1e-40 138.1 1.0 1.5e-40 137.7 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e DUF3616 PF12275.3 AAS52832.1 - 0.026 13.5 0.2 0.035 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) Med25 PF11232.3 AAS52832.1 - 0.045 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 FKBP_C PF00254.23 AAS52833.2 - 2.6e-28 97.8 0.2 2.6e-27 94.6 0.0 2.8 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase Vfa1 PF08432.5 AAS52833.2 - 1.3 8.9 44.1 1.7 8.6 18.1 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 GAGA_bind PF06217.7 AAS52833.2 - 1.9 8.3 21.4 5.8 6.7 0.5 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family DUF1510 PF07423.6 AAS52833.2 - 2.1 7.6 47.0 0.55 9.5 8.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF4604 PF15377.1 AAS52833.2 - 3.1 8.0 48.8 5.3 7.2 21.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) RR_TM4-6 PF06459.7 AAS52833.2 - 5.7 6.7 35.8 5.1 6.9 12.2 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 BNIP3 PF06553.7 AAS52833.2 - 9.4 5.5 19.0 5 6.4 3.9 2.2 2 0 0 2 2 2 0 BNIP3 HMG-CoA_red PF00368.13 AAS52834.2 - 2.7e-158 526.5 0.5 3.5e-158 526.1 0.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 AAS52834.2 - 1.5e-38 131.8 0.1 2.8e-38 131.0 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 AAS52834.2 - 3.4e-08 33.0 6.1 8.4e-08 31.8 4.2 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Zn_clus PF00172.13 AAS52835.1 - 1.8e-05 24.5 8.5 4.1e-05 23.3 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sybindin PF04099.7 AAS52836.1 - 1.5e-19 70.0 0.1 1.9e-19 69.7 0.1 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 AAS52836.1 - 0.02 14.7 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Longin PF13774.1 AAS52836.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 Regulated-SNARE-like domain ENTH PF01417.15 AAS52837.1 - 7.3e-45 151.8 0.2 9.8e-45 151.4 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 AAS52837.1 - 0.0068 15.1 0.0 0.0089 14.7 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 AAS52837.1 - 0.018 14.6 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 VHS domain Pro_isomerase PF00160.16 AAS52838.1 - 3.9e-49 166.8 0.1 4.5e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M28 PF04389.12 AAS52839.1 - 6e-12 45.6 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 AAS52839.1 - 2.2e-11 43.4 0.0 4.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 AAS52839.1 - 0.00065 19.3 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 PA domain Dus PF01207.12 AAS52840.2 - 2.9e-81 272.6 0.0 3.7e-81 272.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-C2H2 PF00096.21 AAS52841.2 - 2.2e-08 33.9 11.3 7.2e-05 22.9 1.4 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AAS52841.2 - 6.1e-07 29.4 14.2 1.8e-05 24.8 3.3 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AAS52841.2 - 2.8e-05 24.1 12.2 0.00048 20.2 1.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 AAS52841.2 - 0.081 13.1 0.4 0.26 11.5 0.3 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-Paramyx-P PF13008.2 AAS52842.1 - 0.18 10.9 3.8 0.29 10.3 2.6 1.4 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein Methyltransf_16 PF10294.4 AAS52843.1 - 1.3e-18 67.0 0.0 2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 AAS52843.1 - 0.00068 20.1 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AAS52843.1 - 0.0054 16.1 0.0 0.018 14.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 AAS52843.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Allantoicase PF03561.10 AAS52844.1 - 5.6e-96 318.1 0.0 8e-53 177.9 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat ATP-synt_J PF04911.7 AAS52845.2 - 7.9e-28 95.6 1.2 8.7e-28 95.5 0.9 1.0 1 0 0 1 1 1 1 ATP synthase j chain Cys_Met_Meta_PP PF01053.15 AAS52846.2 - 3.8e-26 91.2 0.0 6.5e-25 87.2 0.0 2.1 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 AAS52846.2 - 0.023 13.6 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Glyco_hydro_47 PF01532.15 AAS52847.1 - 4.5e-135 450.8 0.6 5.1e-135 450.6 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ctf8 PF09696.5 AAS52848.1 - 5.5e-29 100.4 0.0 7.7e-29 99.9 0.0 1.2 1 0 0 1 1 1 1 Ctf8 DUF2296 PF10058.4 AAS52849.1 - 2e-18 65.8 1.5 1.6e-17 63.0 0.6 2.2 2 0 0 2 2 2 1 Predicted integral membrane metal-binding protein (DUF2296) IncA PF04156.9 AAS52849.1 - 0.0021 17.6 0.1 0.004 16.7 0.1 1.4 1 0 0 1 1 1 1 IncA protein HypA PF01155.14 AAS52849.1 - 0.0033 17.0 0.2 0.0051 16.4 0.2 1.3 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family OmpH PF03938.9 AAS52849.1 - 0.011 15.6 1.2 0.018 14.9 0.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.17 AAS52849.1 - 0.12 12.4 2.2 0.13 12.3 0.6 1.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-ribbon_3 PF13248.1 AAS52849.1 - 0.83 8.9 3.2 0.75 9.0 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 AAS52849.1 - 2.4 8.0 8.0 1.2 9.0 0.6 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain NAC PF01849.13 AAS52850.1 - 2.4e-20 71.8 1.8 5e-20 70.7 0.4 2.0 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 AAS52850.1 - 6.4e-05 22.6 0.2 0.00012 21.7 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain AAA PF00004.24 AAS52851.1 - 7.9e-51 171.7 0.0 1.1e-38 132.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AAS52851.1 - 7.2e-15 54.7 0.0 3.1e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 AAS52851.1 - 5.7e-11 41.8 2.0 8.8e-11 41.2 0.3 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 AAS52851.1 - 9.8e-10 38.6 0.2 0.00053 20.1 0.2 3.4 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 AAS52851.1 - 7.9e-09 35.1 0.9 0.0033 17.1 0.1 2.9 3 0 0 3 3 2 2 Part of AAA domain AAA_17 PF13207.1 AAS52851.1 - 1.8e-08 35.2 0.0 0.0097 16.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 AAS52851.1 - 3e-08 33.8 0.0 0.01 15.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.8 AAS52851.1 - 5.4e-07 28.6 1.2 0.011 14.4 0.1 2.6 2 1 1 3 3 3 2 TIP49 C-terminus Mg_chelatase PF01078.16 AAS52851.1 - 1.1e-06 27.9 0.1 0.0019 17.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 AAS52851.1 - 1.8e-06 27.5 0.3 0.055 12.8 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_5 PF07728.9 AAS52851.1 - 3.5e-06 26.7 0.1 0.0019 17.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AAS52851.1 - 6.7e-06 26.0 0.0 0.078 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 AAS52851.1 - 7.9e-06 25.6 3.4 0.031 13.9 0.1 3.9 4 1 0 5 5 4 2 NACHT domain PhoH PF02562.11 AAS52851.1 - 1.4e-05 24.4 0.0 0.017 14.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_2 PF07724.9 AAS52851.1 - 1.7e-05 24.7 0.0 0.002 18.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 AAS52851.1 - 2.6e-05 24.5 0.1 0.021 15.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 AAS52851.1 - 3e-05 23.1 0.1 0.086 11.8 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 AAS52851.1 - 9.2e-05 21.5 0.0 0.084 11.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 AAS52851.1 - 0.00013 22.1 0.0 0.14 12.3 0.0 2.9 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 AAS52851.1 - 0.00015 22.1 0.7 0.044 14.0 0.0 2.6 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.21 AAS52851.1 - 0.00037 19.9 0.0 0.76 9.2 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.17 AAS52851.1 - 0.00039 19.3 0.0 0.3 9.9 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.7 AAS52851.1 - 0.0017 17.4 0.1 1.1 8.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.1 AAS52851.1 - 0.0019 17.8 2.5 0.45 10.0 0.3 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 AAS52851.1 - 0.0027 17.2 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 AAS52851.1 - 0.0033 17.4 0.1 3.8 7.5 0.0 3.4 2 1 0 2 2 2 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 AAS52851.1 - 0.0036 17.0 1.2 6.7 6.3 0.0 3.4 2 1 1 3 3 3 0 Archaeal ATPase DEAD PF00270.24 AAS52851.1 - 0.0052 16.3 0.6 13 5.2 0.1 3.8 2 2 2 4 4 4 0 DEAD/DEAH box helicase KaiC PF06745.8 AAS52851.1 - 0.0052 15.9 0.2 0.26 10.3 0.0 2.5 2 0 0 2 2 2 1 KaiC Parvo_NS1 PF01057.12 AAS52851.1 - 0.0062 15.4 0.0 2.5 6.8 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ResIII PF04851.10 AAS52851.1 - 0.0066 16.2 0.1 3.5 7.4 0.0 2.9 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit T2SE PF00437.15 AAS52851.1 - 0.0098 14.8 0.0 1.5 7.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.1 AAS52851.1 - 0.01 16.1 1.6 4.9 7.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 AAS52851.1 - 0.013 15.0 0.1 3.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 AAS52851.1 - 0.013 15.4 0.0 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 AAS52851.1 - 0.018 14.4 7.6 2.1 7.7 0.4 3.7 2 2 1 4 4 4 0 AAA domain AAA_11 PF13086.1 AAS52851.1 - 0.019 14.5 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AAS52851.1 - 0.028 13.8 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain IPT PF01745.11 AAS52851.1 - 0.041 13.0 0.4 0.28 10.3 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase AAA_3 PF07726.6 AAS52851.1 - 0.041 13.4 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 AAS52851.1 - 0.045 13.2 0.4 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 AAS52851.1 - 0.13 11.8 0.0 0.79 9.1 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zot PF05707.7 AAS52851.1 - 0.13 11.7 0.1 13 5.2 0.0 2.8 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) PRKCSH PF07915.8 AAS52853.1 - 0.00072 20.3 0.1 0.002 18.9 0.1 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Bromodomain PF00439.20 AAS52854.1 - 2.3e-19 69.0 0.8 1.1e-18 66.9 0.5 2.2 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 AAS52854.1 - 2.5e-07 30.3 0.1 2.6e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Bromodomain associated UQ_con PF00179.21 AAS52855.1 - 1.4e-51 173.5 0.0 1.6e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AAS52855.1 - 5.5e-05 22.9 0.0 6.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AAS52855.1 - 0.00024 20.9 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 AAS52855.1 - 0.0096 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 UEV domain CBF PF03914.12 AAS52856.2 - 2.5e-42 144.1 0.0 2.5e-42 144.1 0.0 2.4 3 0 0 3 3 3 1 CBF/Mak21 family NOC3p PF07540.6 AAS52856.2 - 0.0059 16.8 0.1 0.017 15.3 0.1 1.8 1 0 0 1 1 1 1 Nucleolar complex-associated protein Spore_coat_CotO PF14153.1 AAS52856.2 - 0.41 10.0 6.5 0.069 12.5 0.9 2.3 2 0 0 2 2 2 0 Spore coat protein CotO TEA PF01285.13 AAS52858.2 - 9.8e-34 117.2 0.8 9.8e-34 117.2 0.6 5.5 2 2 2 4 4 4 1 TEA/ATTS domain family FTHFS PF01268.14 AAS52859.1 - 5.1e-256 850.0 2.1 6.7e-256 849.6 1.5 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 AAS52859.1 - 6.1e-68 226.9 1.2 6.1e-68 226.9 0.8 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 AAS52859.1 - 1.6e-36 124.8 2.3 3.9e-36 123.6 0.9 2.2 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Ribosomal_L19e PF01280.15 AAS52860.2 - 1.8e-59 199.7 11.5 1.8e-59 199.7 8.0 1.7 1 1 1 2 2 2 1 Ribosomal protein L19e Med2 PF11214.3 AAS52860.2 - 0.11 12.5 1.1 0.21 11.6 0.8 1.5 1 0 0 1 1 1 0 Mediator complex subunit 2 DUF2423 PF10338.4 AAS52861.1 - 1e-19 70.1 6.9 1e-19 70.1 4.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) DUF2984 PF11203.3 AAS52861.1 - 0.098 12.7 0.5 0.13 12.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2984) DNA_ligase_A_C PF04679.10 AAS52861.1 - 0.1 12.9 0.5 0.13 12.7 0.4 1.2 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region DUF1819 PF08849.6 AAS52861.1 - 0.11 11.9 0.8 1.5 8.2 0.1 2.0 1 1 1 2 2 2 0 Putative inner membrane protein (DUF1819) DUF4632 PF15451.1 AAS52861.1 - 0.12 12.2 0.2 0.23 11.3 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4632) Zn_Tnp_IS1595 PF12760.2 AAS52863.1 - 0.014 15.2 1.6 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2387 PF09526.5 AAS52863.1 - 0.12 12.3 0.4 11 5.9 0.0 2.1 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Fungal_trans PF04082.13 AAS52864.1 - 1.2e-16 60.3 0.2 3.2e-16 58.9 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS52864.1 - 5.2e-10 39.0 9.1 9.8e-10 38.1 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 AAS52865.1 - 8.4e-70 230.5 5.1 1.4e-24 85.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Endonuclea_NS_2 PF13930.1 AAS52866.2 - 0.096 12.7 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease KH_1 PF00013.24 AAS52867.1 - 2.8e-33 113.3 2.2 6.7e-13 48.0 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 AAS52867.1 - 2.5e-22 78.0 6.2 2.2e-07 30.3 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 AAS52867.1 - 3.3e-08 32.9 2.3 0.1 12.1 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 AAS52867.1 - 0.0063 16.2 1.9 2.1 8.1 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain KH_4 PF13083.1 AAS52867.1 - 0.031 13.9 1.7 0.91 9.2 0.0 3.4 3 1 1 4 4 4 0 KH domain HTH_23 PF13384.1 AAS52867.1 - 0.038 13.6 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HSP70 PF00012.15 AAS52868.2 - 2.9e-270 897.3 7.2 3.4e-270 897.1 5.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AAS52868.2 - 1.9e-17 62.8 0.0 2.5e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 AAS52868.2 - 0.0003 20.4 0.0 0.00066 19.3 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 AAS52868.2 - 0.014 14.2 0.4 0.3 9.8 0.1 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 AAS52868.2 - 0.097 12.5 7.1 16 5.3 0.0 3.9 2 2 0 3 3 3 0 Cell division protein FtsA PIP5K PF01504.13 AAS52869.2 - 2e-65 220.3 2.2 3.2e-65 219.7 0.4 2.2 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 AAS52869.2 - 2.3e-26 92.5 0.1 4e-26 91.6 0.1 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 AAS52869.2 - 2.2e-15 56.3 11.5 2.2e-15 56.3 8.0 2.7 4 0 0 4 4 4 1 FYVE zinc finger IBR PF01485.16 AAS52869.2 - 1.2 9.0 10.0 0.2 11.5 3.6 2.3 2 0 0 2 2 2 0 IBR domain Peptidase_M28 PF04389.12 AAS52870.2 - 2.6e-41 141.2 0.0 3.6e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 ABC2_membrane PF01061.19 AAS52871.1 - 2.7e-34 118.1 21.9 3.9e-34 117.6 13.4 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 AAS52871.1 - 9.1e-27 94.0 0.0 1.4e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Laminin_EGF PF00053.19 AAS52871.1 - 0.0085 16.0 7.5 0.0085 16.0 5.2 4.2 2 2 2 4 4 4 2 Laminin EGF-like (Domains III and V) AAA_25 PF13481.1 AAS52871.1 - 0.025 13.9 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 AAS52871.1 - 0.034 14.1 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 AAS52871.1 - 0.035 13.3 0.1 0.076 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 AAS52871.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_pol_Rpc34 PF05158.7 AAS52872.1 - 1.3e-105 353.2 0.4 1.6e-105 352.9 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 AAS52872.1 - 0.014 15.2 0.5 0.053 13.3 0.1 2.0 1 1 1 2 2 2 0 B-block binding subunit of TFIIIC TrmB PF01978.14 AAS52872.1 - 0.027 14.1 1.8 0.23 11.1 0.3 2.5 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.15 AAS52872.1 - 0.033 14.2 0.1 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator Grp1_Fun34_YaaH PF01184.14 AAS52873.2 - 1.2e-91 305.6 16.1 1.4e-91 305.4 11.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family BAR PF03114.13 AAS52874.1 - 4.5e-52 176.8 0.2 6e-52 176.4 0.2 1.2 1 0 0 1 1 1 1 BAR domain DUF1496 PF07383.7 AAS52874.1 - 0.032 13.5 0.1 0.06 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1496) Sterol-sensing PF12349.3 AAS52875.1 - 0.0033 16.9 1.5 0.0033 16.9 1.0 3.5 4 0 0 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation Pkinase PF00069.20 AAS52876.1 - 1.1e-64 218.1 0.0 1.6e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52876.1 - 1.8e-25 89.5 0.0 2.4e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS52876.1 - 0.0023 16.9 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AAS52876.1 - 0.013 15.1 1.1 0.072 12.8 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 AAS52876.1 - 0.09 11.8 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CCDC74_C PF14917.1 AAS52877.2 - 0.012 15.6 3.7 1.6 8.8 0.9 3.1 2 1 1 3 3 3 0 Coiled coil protein 74, C terminal ALIX_LYPXL_bnd PF13949.1 AAS52878.2 - 0.041 12.8 0.6 0.083 11.8 0.4 1.5 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Fib_alpha PF08702.5 AAS52878.2 - 0.05 13.7 0.3 0.14 12.3 0.2 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PAPS_reduct PF01507.14 AAS52879.1 - 1.3e-29 103.2 0.0 5.1e-29 101.3 0.0 1.8 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family CHCH PF06747.8 AAS52880.1 - 5.2e-06 26.2 0.4 6.8e-06 25.8 0.3 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 AAS52880.1 - 0.0056 16.4 0.4 0.0064 16.2 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Sdh5 PF03937.11 AAS52881.1 - 8.9e-26 89.3 0.6 1.3e-25 88.8 0.4 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase E1_DerP2_DerF2 PF02221.10 AAS52882.1 - 2e-27 96.0 0.0 2.5e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 AAS52882.1 - 0.0021 18.1 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 ML-like domain DUF4625 PF15418.1 AAS52882.1 - 0.01 15.9 0.0 0.013 15.6 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4625) Metallophos PF00149.23 AAS52883.1 - 1.8e-43 148.2 0.1 2.3e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AAS52883.1 - 0.0017 18.1 0.0 0.0032 17.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2786 PF10979.3 AAS52883.1 - 0.076 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) PCI PF01399.22 AAS52884.1 - 1.3e-16 60.7 0.0 5.5e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 PCI domain ComX PF05952.7 AAS52884.1 - 0.044 13.2 0.2 0.15 11.6 0.1 2.0 2 0 0 2 2 2 0 Bacillus competence pheromone ComX Smg4_UPF3 PF03467.10 AAS52885.1 - 2e-21 76.7 0.5 2e-21 76.7 0.3 2.2 1 1 1 2 2 2 1 Smg-4/UPF3 family CDC45 PF02724.9 AAS52885.1 - 3.7 5.4 12.4 6.6 4.6 8.6 1.3 1 0 0 1 1 1 0 CDC45-like protein LSM PF01423.17 AAS52886.1 - 2.1e-16 59.1 0.0 4.1e-16 58.2 0.0 1.5 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AAS52886.1 - 0.00096 19.0 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain PRP38 PF03371.10 AAS52887.1 - 2e-52 177.3 0.1 2.4e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 PRP38 family OmdA PF13376.1 AAS52888.1 - 2 8.1 8.0 3.3 7.4 0.0 2.9 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated DER1 PF04511.10 AAS52890.1 - 0.00026 20.5 8.4 0.00044 19.7 5.8 1.3 1 0 0 1 1 1 1 Der1-like family Prefoldin PF02996.12 AAS52891.2 - 3.7e-31 107.2 0.7 5.3e-31 106.7 0.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit Matrilin_ccoil PF10393.4 AAS52891.2 - 0.076 12.3 0.1 0.84 9.0 0.0 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin TMF_DNA_bd PF12329.3 AAS52891.2 - 0.32 10.8 6.2 0.31 10.8 0.4 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IRF-2BP1_2 PF11261.3 AAS52892.2 - 0.01 15.2 0.1 0.029 13.8 0.1 1.7 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger CYSTM PF12734.2 AAS52893.1 - 6.6e-05 22.9 19.9 6.6e-05 22.9 13.8 5.0 3 2 0 3 3 3 2 Cysteine-rich TM module stress tolerance zf-C3HC4_2 PF13923.1 AAS52894.1 - 0.0027 17.6 0.4 0.0072 16.3 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AAS52894.1 - 0.0048 16.5 0.2 0.011 15.3 0.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AAS52894.1 - 0.013 15.1 0.6 0.013 15.1 0.4 1.7 2 0 0 2 2 2 0 zinc-RING finger domain Fer2_3 PF13085.1 AAS52894.1 - 0.031 14.1 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF3696 PF12476.3 AAS52894.1 - 0.36 10.8 2.6 1.6 8.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3696) zf-C3HC4_4 PF15227.1 AAS52894.1 - 0.92 9.4 5.6 0.11 12.3 0.3 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 AAS52894.1 - 9.4 5.9 7.8 0.15 11.7 0.4 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Fibrillarin PF01269.12 AAS52895.1 - 7.4e-109 362.0 0.0 8.9e-109 361.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 AAS52895.1 - 3.7e-06 26.6 0.0 6.8e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 AAS52895.1 - 0.034 13.6 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Steroid_dh PF02544.11 AAS52896.1 - 7.8e-34 116.6 9.7 1.3e-33 115.9 6.7 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Pkinase PF00069.20 AAS52897.1 - 1.8e-39 135.4 0.0 4.9e-20 71.7 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52897.1 - 2.1e-13 49.9 0.0 3.2e-08 32.9 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 AAS52897.1 - 0.028 13.3 0.0 2.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 AAS52897.1 - 0.03 14.0 0.0 0.18 11.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family EMP24_GP25L PF01105.19 AAS52898.1 - 1.2e-20 73.9 0.0 1.4e-20 73.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Amidohydro_1 PF01979.15 AAS52899.1 - 1.1e-26 94.3 0.0 1.8e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 AAS52899.1 - 6.1e-22 78.9 0.6 6.2e-21 75.6 0.4 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 AAS52899.1 - 2.1e-10 40.3 0.1 2.5e-05 23.6 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 AAS52899.1 - 2.8e-10 39.8 0.1 6.2e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 Amidohydrolase HEAT_2 PF13646.1 AAS52900.2 - 2.9e-19 69.1 0.1 3.4e-05 24.0 0.0 8.2 6 3 3 9 9 9 4 HEAT repeats HEAT PF02985.17 AAS52900.2 - 2.1e-18 64.6 8.1 0.0064 16.4 0.0 10.2 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 AAS52900.2 - 4.4e-18 65.1 9.4 2.8e-10 40.3 0.0 8.1 11 0 0 11 11 11 2 HEAT-like repeat Cnd1 PF12717.2 AAS52900.2 - 1.2e-08 35.0 1.2 0.032 14.1 0.0 3.9 3 1 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 AAS52900.2 - 3.8e-07 28.8 0.0 0.036 12.3 0.3 3.6 2 1 0 3 3 3 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 AAS52900.2 - 2.5e-06 27.7 0.0 9 6.7 0.0 4.7 3 1 1 4 4 4 3 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 AAS52900.2 - 0.0043 15.8 4.4 0.49 9.0 0.1 4.8 4 2 1 5 5 5 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 AAS52900.2 - 0.07 12.4 0.0 3.9 6.7 0.0 3.5 4 0 0 4 4 4 0 CLASP N terminal SH3_1 PF00018.23 AAS52901.2 - 3e-09 36.1 0.0 7.5e-09 34.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AAS52901.2 - 1.2e-05 24.8 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAICAR_synt PF01259.13 AAS52902.1 - 7.2e-98 326.6 0.0 8.4e-98 326.4 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Pkinase PF00069.20 AAS52903.1 - 2.4e-59 200.6 0.0 3.2e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52903.1 - 4.5e-32 111.1 0.0 7.8e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AAS52903.1 - 0.049 13.3 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 AAS52904.1 - 9.9e-71 237.9 0.5 3.8e-70 236.0 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52904.1 - 2.5e-52 177.5 0.2 4.8e-52 176.6 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS52904.1 - 2e-08 33.5 0.2 6.8e-07 28.5 0.0 2.3 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 AAS52904.1 - 0.045 13.4 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 AAS52904.1 - 0.055 12.8 0.6 0.5 9.6 0.4 2.3 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL Carn_acyltransf PF00755.15 AAS52905.1 - 1.2e-169 565.2 0.0 1.4e-169 565.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Oxysterol_BP PF01237.13 AAS52906.2 - 1.6e-126 421.5 0.0 4.7e-126 420.0 0.0 1.9 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.2 AAS52906.2 - 5.3e-13 49.1 0.2 5.1e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AAS52906.2 - 5.7e-11 41.6 0.1 5.3e-06 25.9 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 AAS52906.2 - 9e-11 41.6 0.3 5.2e-05 23.3 0.2 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 AAS52906.2 - 4.4e-09 36.6 0.1 9.7e-05 22.7 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PH_8 PF15409.1 AAS52906.2 - 7.6e-09 35.5 0.1 2e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_3 PF13606.1 AAS52906.2 - 4.2e-08 32.6 0.1 0.00084 19.3 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeat PH PF00169.24 AAS52906.2 - 6.1e-08 32.7 0.1 1.5e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 AAS52906.2 - 3.6e-07 30.4 0.3 1.4e-06 28.5 0.2 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain Phos_pyr_kin PF08543.7 AAS52907.2 - 5.8e-72 241.8 0.0 6.5e-72 241.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.12 AAS52907.2 - 0.00015 21.1 0.0 0.0002 20.7 0.0 1.4 1 1 0 1 1 1 1 Carbohydrate kinase PfkB PF00294.19 AAS52907.2 - 0.0076 15.4 0.0 0.031 13.4 0.0 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 AAS52907.2 - 0.62 9.1 5.3 1.2 8.2 0.6 2.6 2 1 0 2 2 2 0 Hydroxyethylthiazole kinase family zf-C2H2 PF00096.21 AAS52908.1 - 0.001 19.2 6.7 0.008 16.4 0.2 3.0 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS52908.1 - 0.0016 18.6 4.6 0.32 11.4 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger His_Phos_1 PF00300.17 AAS52909.1 - 2e-41 141.7 0.0 3.3e-41 141.0 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M49 PF03571.10 AAS52910.1 - 3e-232 771.6 0.6 1.5e-231 769.2 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M49 DUF1700 PF08006.6 AAS52910.1 - 0.16 11.2 0.8 3.8 6.7 0.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) Arginosuc_synth PF00764.14 AAS52911.2 - 2.4e-159 530.5 0.0 2.8e-159 530.3 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 AAS52911.2 - 4.7e-05 23.0 0.0 8.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 AAS52911.2 - 0.00017 20.9 0.0 0.00029 20.1 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 AAS52911.2 - 0.00068 18.2 0.1 0.0011 17.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase SPRY PF00622.23 AAS52912.1 - 0.0019 18.2 0.0 0.016 15.2 0.0 2.4 2 0 0 2 2 2 1 SPRY domain Pkinase PF00069.20 AAS52913.2 - 1.6e-68 230.6 0.0 3.1e-68 229.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52913.2 - 1.2e-30 106.4 0.0 2.3e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DDDD PF10161.4 AAS52913.2 - 0.052 13.1 0.2 0.19 11.3 0.3 1.8 2 0 0 2 2 2 0 Putative mitochondrial precursor protein APH PF01636.18 AAS52913.2 - 0.11 12.1 0.1 0.11 12.1 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Baculo_PP31 PF05311.6 AAS52913.2 - 0.23 10.6 6.3 0.37 10.0 4.4 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) TFIIA PF03153.8 AAS52913.2 - 2.5 7.8 26.2 3.4 7.4 18.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.10 AAS52913.2 - 2.6 7.2 16.5 4 6.6 11.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BTV_NS2 PF04514.7 AAS52913.2 - 7.2 5.3 9.7 10 4.8 6.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PAT1 PF09770.4 AAS52913.2 - 8.1 4.5 39.0 11 4.1 27.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PIF1 PF05970.9 AAS52914.1 - 2.7e-52 177.9 0.0 6.4e-50 170.1 0.0 2.4 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 AAS52914.1 - 2.5e-19 69.6 0.0 5.6e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AAS52914.1 - 1.8e-05 24.9 0.0 6.8e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.9 AAS52914.1 - 4.5e-05 21.4 0.1 0.0019 16.0 0.0 2.2 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 AAS52914.1 - 0.002 18.2 0.0 0.038 14.1 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 AAS52914.1 - 0.0022 17.5 0.1 1 8.7 0.1 2.9 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA PF00004.24 AAS52914.1 - 0.0029 17.8 0.0 0.0064 16.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AAS52914.1 - 0.0035 17.3 1.9 0.012 15.5 0.1 2.5 2 1 0 3 3 2 1 AAA ATPase domain TrwB_AAD_bind PF10412.4 AAS52914.1 - 0.012 14.3 0.1 0.019 13.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 AAS52914.1 - 0.012 15.3 1.0 0.058 13.1 0.3 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) MobB PF03205.9 AAS52914.1 - 0.015 15.0 0.1 0.031 13.9 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 AAS52914.1 - 0.03 14.0 2.9 0.034 13.9 0.8 2.1 2 0 0 2 2 2 0 Part of AAA domain DUF2075 PF09848.4 AAS52914.1 - 0.043 12.7 0.1 0.18 10.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 AAS52914.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 AAS52914.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 AAS52914.1 - 0.19 11.9 0.0 0.47 10.6 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 AAS52914.1 - 0.19 11.6 0.0 1 9.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 AAS52914.1 - 0.2 11.2 1.1 0.82 9.2 0.8 1.9 1 1 0 1 1 1 0 Helicase Pox_A32 PF04665.7 AAS52914.1 - 0.23 10.7 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein MatE PF01554.13 AAS52915.2 - 3.8e-61 205.4 30.9 5.7e-32 110.5 5.1 2.5 2 0 0 2 2 2 2 MatE GCR1_C PF12550.3 AAS52916.1 - 2.4e-14 52.9 0.7 4.7e-14 52.0 0.5 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF3113 PF11310.3 AAS52916.1 - 0.02 14.5 0.1 0.066 12.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) DUF4588 PF15251.1 AAS52916.1 - 0.025 14.5 2.9 0.049 13.5 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3984 PF13136.1 AAS52916.1 - 0.047 12.8 5.6 0.073 12.2 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Zip PF02535.17 AAS52916.1 - 0.33 9.9 5.7 0.42 9.5 3.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_L1 PF00687.16 AAS52917.2 - 9.2e-43 146.1 0.0 1.3e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Elf1 PF05129.8 AAS52918.1 - 1.5e-30 104.7 2.0 2e-30 104.2 1.4 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Ribosomal_L37ae PF01780.14 AAS52918.1 - 0.08 12.8 1.0 0.15 11.9 0.7 1.4 1 0 0 1 1 1 0 Ribosomal L37ae protein family DUF4578 PF15147.1 AAS52918.1 - 0.08 13.3 0.9 0.12 12.7 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4578) zf-C2H2_6 PF13912.1 AAS52918.1 - 0.2 11.5 0.4 0.2 11.5 0.3 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 AAS52918.1 - 1.5 8.9 5.8 5.5 7.1 0.3 2.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Septin PF00735.13 AAS52919.1 - 1.7e-114 381.5 0.0 2.5e-114 381.0 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 AAS52919.1 - 3.8e-05 23.6 0.0 8e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 AAS52919.1 - 6.2e-05 22.2 0.0 0.00018 20.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 AAS52919.1 - 0.00023 21.2 0.2 0.0049 17.0 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 AAS52919.1 - 0.0014 18.2 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 AAS52919.1 - 0.013 14.6 0.1 0.038 13.1 0.0 1.8 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.18 AAS52919.1 - 0.02 14.7 3.4 8.4 6.1 0.0 3.2 2 1 1 3 3 3 0 Dynamin family GTP_EFTU PF00009.22 AAS52919.1 - 0.034 13.5 0.3 0.63 9.4 0.0 2.6 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain Miro PF08477.8 AAS52919.1 - 0.037 14.5 0.0 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 AAS52919.1 - 0.039 13.8 0.1 0.2 11.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 AAS52919.1 - 0.07 13.3 0.0 0.21 11.7 0.0 1.9 1 1 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 AAS52919.1 - 7.5 6.8 7.7 18 5.6 0.5 2.3 2 1 0 2 2 2 0 AAA domain Glycos_transf_3 PF00591.16 AAS52920.1 - 1.2e-77 260.7 0.0 1.7e-77 260.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 AAS52920.1 - 1.2e-10 40.8 0.1 2.5e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Methyltransf_16 PF10294.4 AAS52921.1 - 7.6e-21 74.3 0.0 1.2e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 AAS52921.1 - 3.1e-08 33.3 0.0 4.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS52921.1 - 8.7e-07 29.5 0.0 1.6e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AAS52921.1 - 1.3e-06 28.2 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AAS52921.1 - 3.9e-06 26.3 0.0 6.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 AAS52921.1 - 0.00083 18.7 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 AAS52921.1 - 0.0019 18.2 0.1 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AAS52921.1 - 0.0078 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF43 PF01861.11 AAS52921.1 - 0.011 14.7 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_11 PF08241.7 AAS52921.1 - 0.022 15.2 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 AAS52921.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.11 AAS52921.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Reo_sigmaC PF04582.7 AAS52922.1 - 0.026 13.6 24.3 0.056 12.6 0.5 4.4 2 1 2 4 4 4 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 AAS52922.1 - 5 7.4 28.8 2.1 8.6 0.1 8.0 5 2 2 7 7 7 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 AAS52923.1 - 0.036 14.1 0.2 0.071 13.2 0.1 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2365 PF10157.4 AAS52923.1 - 0.057 13.3 0.6 0.079 12.8 0.4 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) AF0941-like PF14591.1 AAS52923.1 - 0.082 12.9 0.7 0.16 12.0 0.4 1.5 1 1 0 1 1 1 0 AF0941-like DUF948 PF06103.6 AAS52923.1 - 0.11 12.4 0.3 6.7 6.6 0.1 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) VHS PF00790.14 AAS52924.1 - 1.9e-46 157.1 0.1 8.2e-46 155.1 0.0 2.1 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 AAS52924.1 - 1.3e-22 80.2 0.0 2.2e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 AAS52924.1 - 5.5e-15 55.1 3.1 1.5e-14 53.7 2.1 1.7 1 0 0 1 1 1 1 GAT domain SSXT PF05030.7 AAS52924.1 - 0.094 12.3 0.2 0.28 10.7 0.2 1.9 1 0 0 1 1 1 0 SSXT protein (N-terminal region) Muted PF14942.1 AAS52924.1 - 0.33 10.8 4.1 0.6 9.9 2.8 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein HSA PF07529.8 AAS52925.2 - 1.4e-17 63.2 1.7 1.4e-17 63.2 1.2 2.4 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.1 AAS52925.2 - 7.7e-09 35.5 0.1 3.1e-08 33.6 0.1 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AAS52925.2 - 0.0059 16.6 0.0 0.077 13.0 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain BCIP PF13862.1 AAS52926.1 - 2e-49 167.7 0.2 2.6e-49 167.3 0.2 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein SET PF00856.23 AAS52927.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 SET domain EMP24_GP25L PF01105.19 AAS52928.1 - 2.2e-36 125.2 0.2 2.6e-36 125.0 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ThiF PF00899.16 AAS52929.1 - 8.6e-43 145.4 0.0 2.6e-42 143.8 0.0 1.7 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 AAS52929.1 - 6e-23 80.2 0.3 1.1e-22 79.4 0.2 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 AAS52929.1 - 1.7e-10 41.2 0.0 2.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 AAS52929.1 - 0.0022 18.0 0.0 0.011 15.8 0.0 2.2 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase CENP-F_leu_zip PF10473.4 AAS52929.1 - 0.0049 16.7 0.2 0.023 14.5 0.1 1.9 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Herpes_BLRF2 PF05812.7 AAS52929.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Myosin_tail_1 PF01576.14 AAS52929.1 - 0.25 9.0 0.1 0.37 8.4 0.0 1.1 1 0 0 1 1 1 0 Myosin tail IncA PF04156.9 AAS52929.1 - 7.5 6.0 6.8 14 5.2 0.0 2.9 3 0 0 3 3 3 0 IncA protein WD40 PF00400.27 AAS52930.2 - 0.058 13.3 2.5 0.3 11.0 0.1 3.3 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF3317 PF11779.3 AAS52930.2 - 6.1 6.3 5.8 1.4 8.4 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) Cys_Met_Meta_PP PF01053.15 AAS52931.2 - 9.9e-64 215.0 0.0 2.4e-63 213.7 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AAS52931.2 - 0.00058 18.7 0.0 0.00094 18.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 AAS52931.2 - 0.0053 15.7 0.0 0.013 14.4 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II SelA PF03841.8 AAS52931.2 - 0.14 10.8 0.0 0.33 9.6 0.0 1.5 1 1 1 2 2 2 0 L-seryl-tRNA selenium transferase Rad60-SLD PF11976.3 AAS52932.1 - 4.5e-24 83.9 1.7 2.5e-23 81.5 0.3 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 AAS52932.1 - 0.00047 19.5 0.1 0.001 18.4 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.3 AAS52932.1 - 0.083 12.8 0.2 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 GLUT4 regulating protein TUG RNA_pol_Rpb1_5 PF04998.12 AAS52933.2 - 2.3e-94 315.7 0.0 3.6e-94 315.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 AAS52933.2 - 2.1e-84 283.6 0.0 3.2e-84 283.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 AAS52933.2 - 1e-69 233.7 0.0 2.2e-69 232.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 AAS52933.2 - 6.7e-39 133.1 0.0 2.6e-38 131.2 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 AAS52933.2 - 2.9e-31 107.3 0.0 7.1e-31 106.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DSS1_SEM1 PF05160.8 AAS52934.1 - 1e-21 76.4 13.1 1.1e-21 76.3 9.1 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.24 AAS52935.2 - 4e-41 140.3 0.1 1.2e-40 138.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 AAS52935.2 - 2e-05 24.5 0.0 0.0002 21.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AAS52935.2 - 3.4e-05 23.9 0.5 0.011 15.7 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 AAS52935.2 - 0.0001 22.0 0.8 0.00043 20.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AAS52935.2 - 0.00061 19.9 1.3 0.0083 16.2 0.2 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AAS52935.2 - 0.00075 18.6 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 AAS52935.2 - 0.0052 16.0 0.1 0.027 13.7 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 AAS52935.2 - 0.0056 16.5 0.0 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain ThylakoidFormat PF11264.3 AAS52935.2 - 0.0069 16.0 1.5 0.017 14.7 1.0 1.6 1 0 0 1 1 1 1 Thylakoid formation protein IstB_IS21 PF01695.12 AAS52935.2 - 0.0097 15.3 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 AAS52935.2 - 0.0099 16.6 0.0 0.031 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AAS52935.2 - 0.01 15.5 0.1 0.025 14.3 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 AAS52935.2 - 0.014 14.5 0.1 0.038 13.1 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI BLOC1_2 PF10046.4 AAS52935.2 - 0.015 15.4 1.0 0.068 13.3 0.7 2.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF815 PF05673.8 AAS52935.2 - 0.016 14.1 0.0 0.033 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 AAS52935.2 - 0.031 13.6 0.7 0.23 10.8 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 AAS52935.2 - 0.035 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 AAS52935.2 - 0.066 12.7 0.2 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 AAS52935.2 - 0.072 12.6 0.8 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.4 AAS52935.2 - 0.1 12.4 4.9 0.27 11.0 3.4 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KaiC PF06745.8 AAS52935.2 - 0.14 11.2 1.5 0.27 10.3 0.0 2.1 3 0 0 3 3 3 0 KaiC DUF1192 PF06698.6 AAS52935.2 - 0.16 11.8 1.7 0.42 10.4 1.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) WD40 PF00400.27 AAS52936.1 - 7.6e-35 117.5 4.6 3.6e-08 32.9 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 AAS52936.1 - 0.022 13.5 0.1 0.043 12.6 0.0 1.6 1 1 0 1 1 1 0 Coatomer WD associated region BBS2_Mid PF14783.1 AAS52936.1 - 0.038 13.7 0.1 18 5.1 0.0 3.0 3 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 AAS52936.1 - 0.056 12.9 0.0 12 5.3 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain YmzC PF14157.1 AAS52936.1 - 0.27 11.0 1.2 6.6 6.6 0.1 3.2 2 1 2 4 4 4 0 YmzC-like protein Kei1 PF08552.6 AAS52937.1 - 5.1e-53 179.5 6.0 6.8e-53 179.1 4.2 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 RIO1 PF01163.17 AAS52938.1 - 1.1e-72 243.3 0.7 1.1e-72 243.3 0.5 2.3 3 0 0 3 3 3 1 RIO1 family APH PF01636.18 AAS52938.1 - 0.029 14.1 0.0 2.3 7.9 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family CDC45 PF02724.9 AAS52938.1 - 1.3 7.0 17.5 2 6.3 12.2 1.2 1 0 0 1 1 1 0 CDC45-like protein TLD PF07534.11 AAS52939.2 - 9.2e-26 90.4 0.0 2.9e-25 88.8 0.0 1.8 1 1 1 2 2 2 1 TLD NUC153 PF08159.7 AAS52940.2 - 7.2e-14 51.0 3.8 7.2e-14 51.0 2.7 3.2 3 0 0 3 3 3 1 NUC153 domain PH PF00169.24 AAS52942.2 - 3.1e-11 43.4 3.7 2.1e-06 27.8 0.7 2.8 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 AAS52942.2 - 0.00034 20.8 3.8 0.023 14.9 0.6 3.0 2 1 1 3 3 3 2 Pleckstrin homology domain Img2 PF05046.9 AAS52943.2 - 7.9e-24 83.6 0.4 1e-23 83.3 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) WD40 PF00400.27 AAS52944.1 - 3e-84 274.1 34.8 1.2e-13 50.3 0.3 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 AAS52944.1 - 3.1e-09 36.8 0.4 5.4e-05 22.9 0.0 3.5 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 AAS52944.1 - 3.5e-07 28.7 12.8 0.038 12.1 0.0 5.3 2 2 3 5 5 5 3 Nucleoporin Nup120/160 NLE PF08154.7 AAS52944.1 - 8.9e-07 28.8 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nucleoporin_N PF08801.6 AAS52944.1 - 0.00028 19.7 0.7 0.7 8.5 0.1 3.7 2 1 1 3 3 3 2 Nup133 N terminal like Gmad1 PF10647.4 AAS52944.1 - 0.0023 17.3 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 AAS52944.1 - 0.0061 15.6 1.7 0.5 9.4 0.1 3.1 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 AAS52944.1 - 0.0069 14.7 0.1 0.14 10.4 0.1 2.5 2 1 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.7 AAS52944.1 - 0.086 12.5 0.0 2.6 7.8 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 AAS52944.1 - 0.18 11.4 4.4 17 5.0 0.2 3.8 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Pkinase PF00069.20 AAS52945.2 - 1.2e-63 214.7 0.0 2e-63 213.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS52945.2 - 2.3e-34 118.6 0.0 3.7e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS52945.2 - 0.00034 19.6 0.0 0.0033 16.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Metallophos PF00149.23 AAS52946.1 - 8.2e-41 139.5 0.3 1.2e-40 139.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AAS52946.1 - 0.0037 17.1 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ubiquitin PF00240.18 AAS52947.1 - 0.00025 20.3 0.1 0.00031 20.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AAS52947.1 - 0.00055 19.5 0.0 0.0006 19.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 AAS52947.1 - 0.0041 17.6 0.1 0.0045 17.5 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Chorismate_bind PF00425.13 AAS52948.1 - 8.8e-62 208.7 0.0 1.6e-61 207.8 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 AAS52948.1 - 1.2e-33 116.2 0.0 1.8e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 AAS52948.1 - 8.3e-12 45.3 0.0 1.9e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 AAS52948.1 - 7.4e-08 32.0 0.0 1.4e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 HTS PF04204.11 AAS52948.1 - 0.035 12.8 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 Homoserine O-succinyltransferase Glucosamine_iso PF01182.15 AAS52949.1 - 1.4e-49 168.5 0.0 3.6e-49 167.2 0.0 1.6 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PQ-loop PF04193.9 AAS52950.2 - 1.8e-21 75.3 6.6 2.8e-12 45.9 0.1 3.3 4 0 0 4 4 4 2 PQ loop repeat DUF373 PF04123.8 AAS52950.2 - 0.06 12.3 1.4 0.089 11.8 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF373) BCDHK_Adom3 PF10436.4 AAS52951.2 - 5.1e-60 201.7 0.0 7e-60 201.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 AAS52951.2 - 1.5e-17 63.2 0.0 2.9e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AAS52951.2 - 0.0015 18.1 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UreD PF01774.12 AAS52951.2 - 0.033 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 UreD urease accessory protein DUF3215 PF11503.3 AAS52952.1 - 1.8e-34 117.1 0.1 2e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) PI31_Prot_C PF08577.6 AAS52953.2 - 7.7e-11 42.4 18.2 7.7e-11 42.4 12.6 2.1 2 1 0 2 2 2 1 PI31 proteasome regulator DUF2428 PF10350.4 AAS52954.2 - 2.7e-72 242.8 0.0 6.3e-72 241.6 0.0 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.1 AAS52954.2 - 9.9e-05 22.5 1.1 3.3 8.0 0.1 4.8 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 AAS52954.2 - 0.00036 20.3 7.8 0.12 12.4 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat Mg_trans_NIPA PF05653.9 AAS52955.1 - 3.1e-111 371.1 14.4 3.7e-111 370.8 10.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 AAS52955.1 - 1.5e-07 31.6 1.8 1.5e-07 31.6 1.2 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Acyl_transf_3 PF01757.17 AAS52955.1 - 7.1e-05 21.7 7.0 0.01 14.7 2.6 2.2 2 0 0 2 2 2 2 Acyltransferase family EamA PF00892.15 AAS52955.1 - 8e-05 22.6 28.5 0.00012 22.1 5.7 3.4 2 1 1 3 3 3 2 EamA-like transporter family MerT PF02411.10 AAS52955.1 - 0.037 13.8 0.7 0.037 13.8 0.5 2.9 2 1 0 2 2 2 0 MerT mercuric transport protein DUF1686 PF07937.6 AAS52955.1 - 0.052 13.1 5.2 0.74 9.4 3.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1686) gpUL132 PF11359.3 AAS52955.1 - 0.32 10.2 5.1 0.97 8.7 0.0 3.2 3 2 0 3 3 3 0 Glycoprotein UL132 DUF2937 PF11157.3 AAS52955.1 - 0.56 9.5 2.5 0.68 9.2 0.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) eIF-1a PF01176.14 AAS52956.1 - 8.3e-27 92.4 0.2 1.2e-26 91.9 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myb_DNA-bind_6 PF13921.1 AAS52956.1 - 0.0047 16.9 0.0 0.0082 16.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Glyco_transf_20 PF00982.16 AAS52957.1 - 6e-160 532.8 0.2 3e-159 530.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 AAS52957.1 - 1e-34 119.4 0.0 2.3e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase TatD_DNase PF01026.16 AAS52958.2 - 1.7e-32 112.6 0.0 2.3e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase MR_MLE_C PF13378.1 AAS52958.2 - 1 9.3 3.9 2 8.3 0.1 3.0 2 2 0 3 3 3 0 Enolase C-terminal domain-like SAP30_Sin3_bdg PF13867.1 AAS52959.2 - 1.4e-15 56.8 0.2 1.2e-12 47.5 0.0 2.3 1 1 1 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 CUE PF02845.11 AAS52960.1 - 1.8e-11 43.3 0.0 3.8e-11 42.2 0.0 1.6 2 0 0 2 2 2 1 CUE domain WD40 PF00400.27 AAS52961.1 - 1.9e-32 109.9 7.1 1.7e-06 27.6 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 AAS52961.1 - 2.4e-05 24.1 0.2 0.014 15.1 0.0 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 AAS52961.1 - 0.0014 17.5 0.4 0.073 11.8 0.2 2.3 2 1 0 2 2 2 2 Coatomer WD associated region DUF2410 PF10307.4 AAS52962.1 - 1.3e-67 227.0 0.0 1.9e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) DUF221 PF02714.10 AAS52963.2 - 1.6e-89 299.9 21.0 1.6e-89 299.9 14.5 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AAS52963.2 - 1.5e-33 115.5 0.2 1.5e-33 115.5 0.2 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 AAS52963.2 - 1.6e-27 95.2 0.1 3.5e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 AAS52963.2 - 1.2e-16 60.9 0.3 2.2e-16 60.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Sox_C_TAD PF12067.3 AAS52963.2 - 0.13 12.3 2.9 0.072 13.2 0.2 1.8 2 0 0 2 2 2 0 Sox C-terminal transactivation domain Pyrophosphatase PF00719.14 AAS52964.1 - 1.3e-49 167.6 0.0 1.8e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Nup188 PF10487.4 AAS52965.2 - 6.4e-206 686.2 23.3 1.2e-205 685.3 16.1 1.4 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 RRM_6 PF14259.1 AAS52966.1 - 5.5e-33 112.7 0.1 4.7e-12 45.7 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AAS52966.1 - 5.1e-30 102.9 0.0 3.9e-09 36.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS52966.1 - 2.2e-17 62.6 0.0 3.2e-09 36.4 0.0 3.9 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 AAS52966.1 - 0.0074 15.6 0.3 0.016 14.6 0.2 1.6 1 0 0 1 1 1 1 Lsm interaction motif DUF4060 PF13269.1 AAS52966.1 - 0.14 12.1 0.2 5.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4060) FimP PF09766.4 AAS52967.1 - 0.0011 18.1 3.9 0.0016 17.6 2.7 1.2 1 0 0 1 1 1 1 Fms-interacting protein G-patch PF01585.18 AAS52967.1 - 0.0021 17.7 3.9 0.0082 15.9 2.7 2.0 1 0 0 1 1 1 1 G-patch domain DUF1510 PF07423.6 AAS52967.1 - 0.18 11.1 15.7 0.24 10.7 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 AAS52967.1 - 2.1 8.1 10.9 2.8 7.7 7.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 AAS52967.1 - 7.8 6.2 10.8 11 5.7 7.5 1.3 1 0 0 1 1 1 0 DDHD domain PXA PF02194.10 AAS52968.1 - 4e-45 153.6 0.3 4e-45 153.6 0.2 2.6 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 AAS52968.1 - 3.1e-31 107.7 1.0 1.1e-30 105.9 0.7 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 AAS52968.1 - 3.8e-13 49.2 1.1 3.8e-13 49.2 0.8 2.7 4 0 0 4 4 4 1 PX domain RGS PF00615.14 AAS52968.1 - 2.4e-08 34.0 1.7 1.2e-07 31.8 1.2 2.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF2953 PF11167.3 AAS52968.1 - 0.17 11.8 0.0 0.65 9.9 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) RRN9 PF10680.4 AAS52969.1 - 2.8e-18 65.4 0.9 6.7e-18 64.1 0.6 1.7 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor DUF550 PF04447.7 AAS52969.1 - 0.039 13.5 0.1 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF550) YebO PF13974.1 AAS52969.1 - 0.11 12.3 0.7 0.33 10.7 0.5 1.8 1 0 0 1 1 1 0 YebO-like protein Lipoprotein_16 PF03923.8 AAS52969.1 - 0.14 11.5 1.6 4.3 6.6 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized lipoprotein SRP19 PF01922.12 AAS52970.1 - 3.7e-30 104.3 0.0 6e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Pribosyltran PF00156.22 AAS52971.1 - 2.4e-18 66.0 0.6 4.6e-18 65.1 0.3 1.5 2 0 0 2 2 2 1 Phosphoribosyl transferase domain DUF3186 PF11382.3 AAS52971.1 - 0.0048 16.0 0.2 0.0065 15.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3186) zf-HC2 PF13490.1 AAS52971.1 - 0.19 11.7 0.1 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative zinc-finger Fungal_trans PF04082.13 AAS52972.2 - 7e-28 97.2 0.1 1.2e-27 96.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS52972.2 - 3.2e-07 30.1 12.1 6.3e-07 29.2 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.14 AAS52973.1 - 7.8e-41 139.8 0.0 5.8e-35 120.4 0.0 2.8 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 AAS52973.1 - 3.5e-17 63.1 0.1 9.1e-17 61.7 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AAS52973.1 - 2.2e-16 60.0 0.9 1.9e-13 50.4 0.1 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AAS52973.1 - 3.8e-10 39.9 0.0 5.5e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AAS52973.1 - 1.5e-09 37.3 0.5 3.1e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 AAS52973.1 - 6.3e-09 35.7 0.0 1.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 AAS52973.1 - 1.8e-08 33.6 0.0 8.5e-05 21.6 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 AAS52973.1 - 6.7e-08 31.8 2.1 0.0014 17.6 0.1 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 AAS52973.1 - 1.8e-06 26.7 2.1 0.00014 20.4 0.3 2.6 2 1 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 AAS52973.1 - 4.5e-05 23.7 1.0 0.0077 16.6 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 AAS52973.1 - 0.00024 20.7 0.2 0.34 10.4 0.0 2.4 2 0 0 2 2 2 2 Malic enzyme, NAD binding domain Lycopene_cycl PF05834.7 AAS52973.1 - 0.00026 20.0 0.0 0.0026 16.7 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 AAS52973.1 - 0.00077 18.4 0.1 0.0014 17.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 AAS52973.1 - 0.0012 19.0 0.0 0.25 11.6 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 AAS52973.1 - 0.0018 17.4 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 AAS52973.1 - 0.0019 17.3 0.4 0.0053 15.8 0.0 1.9 3 0 0 3 3 3 1 FAD binding domain Amino_oxidase PF01593.19 AAS52973.1 - 0.0022 17.1 0.0 0.022 13.8 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 AAS52973.1 - 0.0024 17.9 0.0 0.38 10.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 AAS52973.1 - 0.016 14.9 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.7 AAS52973.1 - 0.033 13.5 1.5 7.3 5.9 0.0 2.8 2 1 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_C PF01262.16 AAS52973.1 - 0.034 13.7 0.5 0.54 9.7 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 AAS52973.1 - 0.06 12.4 0.2 0.12 11.3 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase DJ-1_PfpI PF01965.19 AAS52973.1 - 0.11 11.9 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 DJ-1/PfpI family 3HCDH_N PF02737.13 AAS52973.1 - 0.14 11.8 1.7 2.4 7.7 0.3 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 AAS52973.1 - 1.6 7.5 5.8 0.75 8.5 0.1 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 AAS52973.1 - 2.7 6.5 4.5 0.42 9.1 0.3 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Ctr PF04145.10 AAS52974.1 - 7.4e-26 90.9 12.7 8e-14 51.9 3.3 2.1 1 1 1 2 2 2 2 Ctr copper transporter family 7TM_GPCR_Srv PF10323.4 AAS52974.1 - 0.00083 18.5 0.4 0.00099 18.3 0.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv ABC2_membrane_4 PF12730.2 AAS52974.1 - 0.012 14.7 1.4 0.015 14.4 0.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1286 PF06939.6 AAS52974.1 - 0.26 11.4 5.3 0.67 10.1 3.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1286) DUF1056 PF06341.6 AAS52974.1 - 1.2 9.2 7.2 1.5 8.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) DctQ PF04290.7 AAS52974.1 - 2.2 8.0 9.8 4 7.1 0.7 2.0 1 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Enolase_C PF00113.17 AAS52975.1 - 4.2e-154 511.8 0.0 5.6e-154 511.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 AAS52975.1 - 5.6e-59 197.8 0.5 9.5e-59 197.0 0.3 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 AAS52975.1 - 0.00054 20.4 0.0 0.0015 19.0 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 AAS52975.1 - 0.037 12.9 0.2 0.091 11.6 0.0 1.8 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Spc97_Spc98 PF04130.8 AAS52976.1 - 3.1e-94 316.2 7.2 4e-94 315.8 5.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Proteasome PF00227.21 AAS52977.1 - 4.5e-54 182.6 0.1 5.9e-54 182.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AAS52977.1 - 2.2e-13 49.2 0.1 3.9e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Bromodomain PF00439.20 AAS52978.1 - 3.6e-25 87.6 1.3 7.3e-25 86.7 0.9 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 AAS52978.1 - 1.1e-09 38.2 0.4 5.1e-09 36.1 0.2 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AAS52978.1 - 2.7e-08 33.7 0.1 4.8e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AAS52978.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AAS52978.1 - 0.0055 16.6 0.1 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ThiF PF00899.16 AAS52979.1 - 2.5e-32 111.5 0.0 4.3e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 AAS52979.1 - 0.00019 21.5 0.0 0.0024 17.9 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase LpxB PF02684.10 AAS52979.1 - 0.01 14.4 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase ApbA PF02558.11 AAS52979.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 AAS52979.1 - 0.052 12.6 0.0 2.9 6.9 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NMD3 PF04981.8 AAS52980.2 - 7.9e-77 257.5 2.3 1.4e-76 256.7 1.6 1.4 1 0 0 1 1 1 1 NMD3 family HypA PF01155.14 AAS52980.2 - 0.83 9.3 5.8 15 5.3 0.0 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_6 PF14599.1 AAS52980.2 - 1.5 8.6 10.3 0.25 11.1 0.1 3.5 2 1 1 3 3 3 0 Zinc-ribbon PqqD PF05402.7 AAS52980.2 - 3.5 7.7 5.6 4.5 7.3 0.6 2.5 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) FYVE PF01363.16 AAS52980.2 - 4.4 7.2 7.2 3.6 7.5 2.6 2.4 2 0 0 2 2 2 0 FYVE zinc finger DUF2702 PF10863.3 AAS52981.1 - 1.8e-55 186.6 6.1 2.4e-55 186.2 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2702) Use1 PF09753.4 AAS52981.1 - 0.064 12.6 4.1 0.094 12.1 2.8 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 PBP1_TM PF14812.1 AAS52981.1 - 3.8 7.8 11.8 28 5.0 8.2 2.2 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DEAD PF00270.24 AAS52982.1 - 5.2e-40 136.6 0.3 6e-39 133.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS52982.1 - 2.2e-29 101.0 0.1 4e-29 100.2 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS52982.1 - 0.004 17.0 0.0 0.012 15.3 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit GTP1_OBG PF01018.17 AAS52983.1 - 2.9e-33 114.7 5.0 2e-23 82.7 3.0 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 AAS52983.1 - 1.5e-21 76.4 0.0 2.5e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AAS52983.1 - 1.4e-09 37.4 0.0 3.1e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 AAS52983.1 - 6.8e-09 35.2 0.0 1.6e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 AAS52983.1 - 0.00024 21.5 0.0 0.00049 20.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 AAS52983.1 - 0.00033 20.5 0.0 0.15 11.9 0.0 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 AAS52983.1 - 0.00075 18.9 0.0 0.035 13.5 0.0 2.4 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Ras PF00071.17 AAS52983.1 - 0.002 17.5 0.0 0.0051 16.2 0.0 1.7 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 AAS52983.1 - 0.0021 17.3 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MSC PF09402.5 AAS52984.2 - 2.2e-139 463.8 3.8 2.2e-139 463.8 2.7 1.7 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain HeH PF12949.2 AAS52984.2 - 2.5e-13 49.3 0.2 7.3e-13 47.8 0.2 1.9 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.22 AAS52984.2 - 0.085 12.3 0.3 1.1 8.8 0.0 2.9 2 0 0 2 2 2 0 SAP domain HECT PF00632.20 AAS52985.2 - 6.8e-92 307.9 2.4 4.8e-91 305.2 0.0 3.2 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 AAS52985.2 - 2.4e-82 276.9 3.6 2.4e-82 276.9 2.5 2.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 AAS52985.2 - 1.1e-45 156.1 1.5 2e-45 155.1 0.1 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) DUF4414 PF14377.1 AAS52985.2 - 1.7e-11 43.9 0.3 5.3e-11 42.4 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) Rad52_Rad22 PF04098.10 AAS52986.1 - 7.3e-57 191.4 0.0 1e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Ndc1_Nup PF09531.5 AAS52987.2 - 4.4e-137 458.0 11.2 6.4e-137 457.5 7.8 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Na_H_Exchanger PF00999.16 AAS52988.1 - 4.6e-63 213.0 37.3 5.9e-63 212.6 25.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Myc_target_1 PF15179.1 AAS52988.1 - 0.076 12.6 1.4 0.2 11.2 0.9 1.7 1 0 0 1 1 1 0 Myc target protein 1 Guanylate_kin PF00625.16 AAS52989.1 - 6.5e-70 234.2 0.0 7.2e-70 234.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 AAS52989.1 - 8.8e-07 29.2 0.0 1.4e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AAS52989.1 - 2.3e-06 27.7 0.2 1.7e-05 24.8 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AAS52989.1 - 3.3e-06 27.2 0.0 0.00012 22.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AAS52989.1 - 3.8e-06 26.8 0.0 1.5e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AAS52989.1 - 1e-05 26.3 0.0 2.3e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 AAS52989.1 - 0.00068 19.9 0.1 0.00084 19.6 0.0 1.6 1 1 0 1 1 1 1 ABC transporter Miro PF08477.8 AAS52989.1 - 0.0014 19.0 0.0 0.0025 18.3 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein AAA_14 PF13173.1 AAS52989.1 - 0.0016 18.3 0.0 0.0028 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AAS52989.1 - 0.0018 18.2 0.0 0.0036 17.2 0.0 1.6 2 0 0 2 2 1 1 AAA domain DUF258 PF03193.11 AAS52989.1 - 0.0019 17.4 0.0 0.0028 16.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 AAS52989.1 - 0.0023 17.4 0.2 0.0073 15.8 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 AAS52989.1 - 0.0023 17.8 0.0 0.0049 16.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 AAS52989.1 - 0.0027 17.8 0.0 0.0087 16.2 0.0 1.7 2 1 0 2 2 1 1 RNA helicase AAA_10 PF12846.2 AAS52989.1 - 0.0028 17.1 0.2 0.0059 16.0 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain KAP_NTPase PF07693.9 AAS52989.1 - 0.004 16.2 0.3 0.022 13.7 0.2 1.9 1 1 0 1 1 1 1 KAP family P-loop domain NACHT PF05729.7 AAS52989.1 - 0.004 16.8 0.0 0.0067 16.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.10 AAS52989.1 - 0.0096 15.6 0.1 0.023 14.4 0.0 1.8 1 1 1 2 2 2 1 NTPase AAA PF00004.24 AAS52989.1 - 0.01 16.0 0.1 0.068 13.3 0.0 2.1 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 AAS52989.1 - 0.01 14.7 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 AAS52989.1 - 0.011 16.0 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AAS52989.1 - 0.012 15.3 0.0 0.012 15.3 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 AAS52989.1 - 0.017 14.2 0.1 0.04 13.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.14 AAS52989.1 - 0.017 14.5 0.0 0.058 12.8 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.4 AAS52989.1 - 0.019 13.9 0.0 0.019 13.9 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 AAS52989.1 - 0.019 14.7 0.1 0.069 12.9 0.0 2.0 2 1 0 2 2 2 0 Part of AAA domain Viral_helicase1 PF01443.13 AAS52989.1 - 0.022 14.2 0.0 0.04 13.4 0.0 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 AAS52989.1 - 0.11 11.1 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 AAS52989.1 - 0.11 12.0 0.4 0.2 11.1 0.2 1.7 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.9 AAS52989.1 - 0.12 12.1 0.5 1.4 8.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.7 AAS52989.1 - 0.15 11.3 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein HIG_1_N PF04588.8 AAS52990.1 - 4.3e-20 71.1 0.5 5.9e-20 70.7 0.4 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PsbJ PF01788.12 AAS52990.1 - 0.024 14.1 0.2 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 PsbJ PEARLI-4 PF05278.7 AAS52990.1 - 0.044 13.1 5.2 0.061 12.6 3.6 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF2514 PF10721.4 AAS52990.1 - 0.067 12.8 7.9 0.17 11.5 5.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) IncA PF04156.9 AAS52990.1 - 0.076 12.6 7.6 0.13 11.8 5.3 1.4 1 0 0 1 1 1 0 IncA protein DUF724 PF05266.9 AAS52990.1 - 3.6 7.1 10.4 5.6 6.5 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ubiquitin PF00240.18 AAS52991.2 - 0.00058 19.2 0.0 0.0032 16.8 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.1 AAS52991.2 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like AhpC-TSA PF00578.16 AAS52992.1 - 1.6e-35 121.4 0.1 7.3e-35 119.3 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 AAS52992.1 - 6.9e-20 71.0 0.3 9.7e-20 70.6 0.0 1.3 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.4 AAS52992.1 - 6.6e-11 41.6 0.2 1.2e-10 40.8 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Metallophos PF00149.23 AAS52993.2 - 1.8e-08 34.0 0.4 3.5e-08 33.0 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NDUF_B8 PF05821.6 AAS52993.2 - 0.0067 16.0 0.5 0.013 15.1 0.4 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Homeobox PF00046.24 AAS52994.1 - 2.7e-18 65.3 7.5 5.2e-18 64.4 5.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 AAS52994.1 - 0.00043 19.9 0.3 0.0014 18.3 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain Ribosomal_S13 PF00416.17 AAS52995.1 - 1.6e-42 144.3 1.6 1.8e-42 144.1 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 AAS52995.1 - 0.00023 19.8 0.1 0.00035 19.2 0.0 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 AAS52995.1 - 0.097 12.7 0.3 0.36 10.8 0.1 2.0 2 1 0 2 2 2 0 Helix-hairpin-helix motif Ribosomal_L4 PF00573.17 AAS52996.2 - 6.9e-49 165.8 0.0 8.4e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family U3_assoc_6 PF08640.6 AAS52997.2 - 2.7e-33 113.5 11.8 3.8e-33 113.1 0.5 3.5 4 1 0 4 4 4 2 U3 small nucleolar RNA-associated protein 6 Suf PF05843.9 AAS52997.2 - 0.001 18.8 0.7 0.001 18.8 0.5 3.3 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) NRDE-2 PF08424.5 AAS52997.2 - 0.0017 17.2 3.8 0.0072 15.2 0.5 2.4 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 AAS52997.2 - 0.011 16.2 0.0 11 7.0 0.0 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat CTD_bind PF04818.8 AAS52997.2 - 0.023 14.9 0.4 0.12 12.6 0.3 2.3 1 0 0 1 1 1 0 RNA polymerase II-binding domain. HAT PF02184.11 AAS52997.2 - 0.048 13.4 0.4 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat TPR_17 PF13431.1 AAS52997.2 - 0.076 13.2 0.1 39 4.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ZZ PF00569.12 AAS52998.1 - 1.3e-16 59.8 7.6 2.7e-16 58.8 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 AAS52998.1 - 4.5e-12 45.9 0.2 7.1e-10 38.8 0.0 2.7 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 AAS52998.1 - 6.1e-07 29.3 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AAS52998.1 - 0.00093 19.2 0.0 0.0026 17.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ribosomal_S17e PF00833.13 AAS52999.1 - 4.4e-56 187.8 0.6 5.1e-56 187.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 ECM11 PF15463.1 AAS53000.1 - 2.4e-26 92.6 0.1 2.4e-26 92.6 0.1 2.6 3 0 0 3 3 3 1 Extracellular mutant protein 11 RPAP1_N PF08621.5 AAS53000.1 - 0.36 10.4 3.6 1.3 8.6 2.5 1.9 1 1 0 1 1 1 0 RPAP1-like, N-terminal FAD-oxidase_C PF02913.14 AAS53001.1 - 1.4e-53 181.7 0.0 2.1e-53 181.2 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AAS53001.1 - 6.9e-37 126.0 0.1 1.2e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DUF4356 PF14266.1 AAS53001.1 - 0.0098 14.3 0.0 0.014 13.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4356) DUF676 PF05057.9 AAS53002.2 - 1e-47 162.2 0.0 1.5e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 AAS53002.2 - 0.00036 20.1 0.0 0.0008 19.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 AAS53002.2 - 0.012 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.8 AAS53002.2 - 0.023 14.2 0.1 0.054 13.0 0.1 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF3868 PF12984.2 AAS53002.2 - 0.059 12.8 0.0 3.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3868) Abhydrolase_1 PF00561.15 AAS53002.2 - 0.096 12.2 0.1 6.2 6.3 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AAS53002.2 - 0.098 12.5 0.0 0.28 11.0 0.0 1.7 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AAS53002.2 - 0.13 11.9 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Med13_C PF06333.7 AAS53003.1 - 4e-94 315.5 0.3 4.6e-92 308.7 0.2 2.4 1 1 0 1 1 1 1 Mediator complex subunit 13 C-terminal Nse5 PF08691.5 AAS53004.2 - 1.5e-149 498.8 0.1 1.7e-149 498.5 0.1 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Pribosyltran PF00156.22 AAS53005.1 - 1.2e-16 60.6 0.0 1.5e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AAS53005.1 - 0.0026 16.9 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DOT1 PF08123.8 AAS53006.2 - 9e-90 299.4 0.0 1.3e-89 298.9 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.15 AAS53006.2 - 0.0042 16.1 0.0 0.0083 15.2 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 AAS53006.2 - 0.024 15.2 0.0 0.046 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 AAS53006.2 - 0.079 11.9 0.0 0.2 10.7 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase UDG PF03167.14 AAS53007.1 - 6.2e-24 84.2 0.0 9.3e-24 83.6 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily LRS4 PF10422.4 AAS53009.2 - 3.9e-47 160.7 0.0 5.5e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Atg14 PF10186.4 AAS53009.2 - 0.0023 16.9 1.5 0.0029 16.5 1.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 HTH_38 PF13936.1 AAS53009.2 - 0.1 12.1 1.3 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain DUF972 PF06156.8 AAS53009.2 - 0.31 11.4 2.9 0.52 10.6 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) OST3_OST6 PF04756.8 AAS53010.2 - 3.9e-19 68.7 9.6 6.5e-19 68.0 6.6 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 AAS53010.2 - 0.06 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin EamA PF00892.15 AAS53011.1 - 3.6e-11 43.1 31.7 4.4e-07 29.9 5.9 3.2 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 AAS53011.1 - 5.6e-07 29.3 22.3 0.0008 19.0 4.0 3.0 3 0 0 3 3 3 2 Triose-phosphate Transporter family DUF914 PF06027.7 AAS53011.1 - 1.2e-06 27.6 8.2 1.2e-06 27.6 5.7 1.6 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 AAS53011.1 - 0.00031 19.7 13.3 0.00031 19.7 9.2 1.5 2 0 0 2 2 2 1 UAA transporter family 7tm_7 PF08395.7 AAS53011.1 - 0.017 14.1 0.4 0.017 14.1 0.3 2.9 3 1 0 3 3 3 0 7tm Chemosensory receptor EmrE PF13536.1 AAS53011.1 - 0.19 11.9 26.4 0.091 12.9 4.1 3.4 3 0 0 3 3 3 0 Multidrug resistance efflux transporter PIG-P PF08510.7 AAS53013.1 - 2.4e-39 133.8 0.8 2.8e-39 133.6 0.5 1.1 1 0 0 1 1 1 1 PIG-P Metallophos PF00149.23 AAS53014.2 - 1.1e-38 132.6 0.2 1.7e-38 132.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GHMP_kinases_N PF00288.21 AAS53015.1 - 4.7e-23 81.0 0.2 1.2e-22 79.6 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AAS53015.1 - 2e-08 34.3 0.5 1.1e-07 31.8 0.0 2.4 1 1 1 2 2 2 1 GHMP kinases C terminal Mtc PF03820.12 AAS53016.1 - 4.9e-122 406.3 0.1 5.5e-122 406.2 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier WD40 PF00400.27 AAS53017.2 - 4.2e-37 124.6 4.8 2.3e-08 33.6 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 AAS53017.2 - 1.7e-24 85.5 0.1 3.4e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 AAS53017.2 - 1.3e-08 33.4 7.2 0.00018 19.7 0.5 3.4 2 2 1 3 3 3 3 Nucleoporin Nup120/160 N2227 PF07942.7 AAS53018.1 - 9.2e-75 251.0 0.1 1.2e-74 250.6 0.1 1.1 1 0 0 1 1 1 1 N2227-like protein MFS_1 PF07690.11 AAS53019.1 - 6.9e-28 97.3 40.5 6.9e-28 97.3 28.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AAS53019.1 - 7.2e-06 24.8 0.3 7.2e-06 24.8 0.2 3.8 2 2 2 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.8 AAS53019.1 - 0.0026 16.0 4.0 0.0026 16.0 2.7 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Tubulin_3 PF14881.1 AAS53020.1 - 1.4e-22 80.0 0.0 2.2e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 AAS53020.1 - 8.9e-16 57.9 0.0 1.8e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 AAS53020.1 - 0.0033 17.2 0.0 0.0068 16.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain IPPT PF01715.12 AAS53021.1 - 2.5e-78 262.5 0.0 3.5e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 AAS53021.1 - 1.3e-05 25.9 1.1 5.4e-05 23.9 0.0 2.5 3 2 0 3 3 3 1 AAA domain IPT PF01745.11 AAS53021.1 - 0.00051 19.2 0.1 0.0077 15.4 0.0 2.8 3 1 1 4 4 4 1 Isopentenyl transferase AAA_18 PF13238.1 AAS53021.1 - 0.00095 19.4 0.1 0.003 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AAS53021.1 - 0.0039 17.0 0.0 0.05 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 AAS53021.1 - 0.0048 16.0 0.0 0.013 14.6 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 AAS53021.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.1 AAS53021.1 - 0.027 14.5 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 AAS53021.1 - 0.038 13.4 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 AAS53021.1 - 0.053 12.7 0.1 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Hpr_kinase_C PF07475.7 AAS53021.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain BRO1 PF03097.13 AAS53022.1 - 3.4e-86 289.3 2.8 6.1e-86 288.5 1.9 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 AAS53022.1 - 2.4e-16 59.5 8.0 2.4e-16 59.5 5.6 2.5 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV Myb_DNA-binding PF00249.26 AAS53024.1 - 3.2e-16 59.1 0.2 3e-12 46.4 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AAS53024.1 - 2.2e-15 56.4 0.0 3e-11 43.2 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 AAS53024.1 - 0.025 14.4 0.6 3.1 7.7 0.1 2.7 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ATC_hydrolase PF14196.1 AAS53024.1 - 0.41 11.0 3.6 60 4.0 0.1 3.1 3 0 0 3 3 3 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase DUF776 PF05604.6 AAS53025.1 - 0.075 13.2 1.0 0.12 12.5 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF776) DnaJ PF00226.26 AAS53026.2 - 1.1e-27 95.4 1.3 2e-27 94.6 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 AAS53026.2 - 1.1e-14 54.1 18.3 2e-14 53.3 12.7 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 AAS53026.2 - 1.7e-09 37.4 0.0 3.1e-08 33.4 0.0 2.4 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 AAS53026.2 - 0.67 9.6 12.3 1.2 8.8 1.3 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family PADR1 PF08063.7 AAS53026.2 - 0.72 9.2 6.4 11 5.4 0.3 3.1 2 1 1 3 3 3 0 PADR1 (NUC008) domain DZR PF12773.2 AAS53026.2 - 2 8.2 14.0 1.1e+02 2.7 9.7 2.3 1 1 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 AAS53026.2 - 2.1 7.9 15.9 0.44 10.0 0.4 3.5 3 1 0 3 3 3 0 A2L zinc ribbon domain Glyco_hydro_72 PF03198.9 AAS53027.1 - 2.6e-120 401.1 2.1 3.3e-120 400.8 1.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 AAS53027.1 - 3.9e-08 32.5 0.4 1e-07 31.1 0.3 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 AAS53027.1 - 0.00031 20.0 0.5 0.003 16.8 0.4 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.20 AAS53028.2 - 2.8e-40 138.1 0.1 8.9e-21 74.1 0.2 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53028.2 - 4.1e-10 39.1 0.9 7.4e-06 25.2 0.3 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase RRM_1 PF00076.17 AAS53029.1 - 2.4e-09 36.6 0.0 3.6e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AAS53029.1 - 1.4e-08 34.3 0.0 1.9e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 AAS53029.1 - 9.2e-08 31.9 0.0 1.4e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS53029.1 - 2.1e-06 27.4 0.0 3.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GATase PF00117.23 AAS53030.1 - 6.5e-42 143.1 0.0 1.2e-41 142.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 AAS53030.1 - 2.3e-41 139.4 0.0 4.9e-41 138.3 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain Peptidase_C26 PF07722.8 AAS53030.1 - 2.8e-08 33.4 0.1 1.4e-07 31.1 0.0 2.3 2 1 0 2 2 2 1 Peptidase C26 NAD_synthase PF02540.12 AAS53030.1 - 5.4e-08 32.0 0.0 1.1e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.11 AAS53030.1 - 0.0038 15.8 0.0 0.0083 14.7 0.0 1.6 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.8 AAS53030.1 - 0.012 14.8 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 AAS53030.1 - 0.02 13.9 0.1 0.036 13.1 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase Asn_synthase PF00733.16 AAS53030.1 - 0.036 13.5 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase PAPS_reduct PF01507.14 AAS53030.1 - 0.046 13.5 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.9 AAS53030.1 - 0.063 12.7 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) HEM4 PF02602.10 AAS53031.2 - 9.5e-41 139.5 0.0 1.1e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD AAA_25 PF13481.1 AAS53031.2 - 0.014 14.7 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain TRAPPC10 PF12584.3 AAS53032.2 - 3.4e-10 39.6 0.1 6.5e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 GHMP_kinases_N PF00288.21 AAS53034.1 - 4.5e-13 49.0 0.1 9.8e-13 47.9 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AAS53034.1 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal FSH1 PF03959.8 AAS53036.1 - 1.2e-59 201.3 0.0 1.4e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 AAS53036.1 - 1.8e-05 24.5 0.0 2.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AAS53036.1 - 5.1e-05 22.8 0.0 9.8e-05 21.8 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 AAS53036.1 - 0.015 15.1 0.0 3 7.6 0.0 2.4 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF416 PF04222.7 AAS53036.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF416) CDP-OH_P_transf PF01066.16 AAS53037.1 - 2e-11 44.0 4.8 3.6e-11 43.2 3.3 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase ACOX PF01756.14 AAS53038.2 - 3e-43 147.3 0.1 4.7e-43 146.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 AAS53038.2 - 1.3e-16 59.8 0.2 2.7e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 AAS53038.2 - 2.4e-13 50.4 0.1 4.4e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 AAS53038.2 - 8.7e-07 29.1 0.0 1.6e-05 25.0 0.0 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RPAP1_N PF08621.5 AAS53038.2 - 0.064 12.8 0.4 15 5.3 0.0 2.5 2 0 0 2 2 2 0 RPAP1-like, N-terminal Clathrin PF00637.15 AAS53039.2 - 1.2e-195 640.9 51.4 1.3e-30 105.9 1.3 8.4 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 AAS53039.2 - 5.5e-24 83.8 0.9 1.8e-23 82.2 0.1 2.4 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.5 AAS53039.2 - 2.7e-11 42.2 0.2 7.7e-11 40.7 0.1 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Clathrin_propel PF01394.15 AAS53039.2 - 2.3e-10 40.0 0.8 3.7 8.0 0.0 5.8 5 0 0 5 5 5 4 Clathrin propeller repeat TPR_12 PF13424.1 AAS53039.2 - 5.7e-05 22.9 4.5 1.7 8.6 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat Vps39_1 PF10366.4 AAS53039.2 - 8.8e-05 22.4 17.6 0.018 15.0 0.2 6.7 7 0 0 7 7 7 2 Vacuolar sorting protein 39 domain 1 TPR_7 PF13176.1 AAS53039.2 - 0.0058 16.3 10.0 16 5.5 0.1 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat PPR_3 PF13812.1 AAS53039.2 - 0.019 15.1 0.0 61 4.2 0.0 5.4 7 0 0 7 7 7 0 Pentatricopeptide repeat domain TPR_1 PF00515.23 AAS53039.2 - 0.024 14.2 9.8 6.5 6.5 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 AAS53039.2 - 0.093 13.0 6.3 3.9 7.8 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat SPT16 PF08644.6 AAS53040.2 - 9.2e-54 181.4 0.1 2.5e-53 180.0 0.1 1.8 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 AAS53040.2 - 7.9e-43 145.8 0.2 1.2e-41 141.9 0.0 2.6 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 AAS53040.2 - 9.7e-27 93.8 0.0 1.7e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 AAS53040.2 - 8e-19 67.4 0.2 9.5e-18 63.9 0.1 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like TBP PF00352.16 AAS53040.2 - 0.071 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) AMPKBI PF04739.10 AAS53041.1 - 9.7e-31 105.6 2.3 9.7e-31 105.6 1.6 2.6 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain AJAP1_PANP_C PF15298.1 AAS53041.1 - 0.26 11.1 0.1 0.26 11.1 0.0 2.4 2 1 0 2 2 2 0 AJAP1/PANP C-terminus zf-C4H2 PF10146.4 AAS53041.1 - 1.2 9.0 5.2 2.6 8.0 3.6 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein tRNA-synt_2 PF00152.15 AAS53042.2 - 1.8e-67 227.5 0.0 2.3e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 AAS53042.2 - 5.2e-06 25.8 0.4 0.00032 19.9 0.0 2.5 2 1 1 3 3 3 1 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 AAS53042.2 - 1.4e-05 24.8 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 AAS53042.2 - 0.019 14.5 0.0 6.8 6.2 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) RNase_HII PF01351.13 AAS53043.2 - 3.4e-58 196.5 0.0 4.2e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII 2-oxoacid_dh PF00198.18 AAS53044.1 - 5.2e-74 248.3 0.0 6.9e-74 247.9 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 AAS53044.1 - 3.6e-17 61.7 0.1 6.6e-17 60.9 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 AAS53044.1 - 1.7e-16 59.5 0.1 1.7e-16 59.5 0.1 2.5 3 0 0 3 3 3 1 e3 binding domain Tom7 PF08038.7 AAS53045.1 - 5e-19 67.4 0.0 6.3e-19 67.1 0.0 1.1 1 0 0 1 1 1 1 TOM7 family Mito_carr PF00153.22 AAS53046.1 - 5.5e-61 202.3 2.0 1.3e-22 79.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L13 PF00572.13 AAS53047.1 - 3.6e-25 88.4 0.0 6.8e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 Fork_head PF00250.13 AAS53049.2 - 4.9e-37 125.8 1.2 9.8e-37 124.8 0.3 2.0 2 0 0 2 2 2 1 Fork head domain FHA PF00498.21 AAS53049.2 - 1e-11 44.7 0.1 3.2e-11 43.1 0.1 1.9 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.14 AAS53049.2 - 0.0031 17.5 0.2 0.016 15.2 0.0 2.2 2 0 0 2 2 2 1 linker histone H1 and H5 family Fungal_trans PF04082.13 AAS53050.2 - 1.1e-26 93.3 0.1 1.7e-26 92.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS53050.2 - 5.7e-11 42.1 12.0 1e-10 41.3 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUN PF03856.8 AAS53052.2 - 8.4e-106 352.8 10.1 1.2e-105 352.3 7.0 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF605 PF04652.11 AAS53052.2 - 5.1 6.3 17.8 7.6 5.8 12.3 1.2 1 0 0 1 1 1 0 Vta1 like SOG2 PF10428.4 AAS53052.2 - 9.7 4.7 16.8 13 4.2 11.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein adh_short PF00106.20 AAS53053.1 - 1.7e-30 106.1 0.0 2.3e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AAS53053.1 - 5.7e-15 55.7 0.0 7.5e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AAS53053.1 - 7.7e-12 45.2 0.0 1.2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AAS53053.1 - 3.8e-07 30.2 0.0 6.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 AAS53053.1 - 9.7e-07 28.2 0.0 3.3e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 AAS53053.1 - 1.5e-06 27.8 0.0 9.4e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 AAS53053.1 - 0.00012 21.1 0.0 0.00022 20.2 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 AAS53053.1 - 0.034 13.9 0.0 0.089 12.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 AAS53053.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Transket_pyr PF02779.19 AAS53054.2 - 1.3e-63 213.7 0.0 2.3e-63 212.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 AAS53054.2 - 6.5e-54 182.6 0.0 8.9e-54 182.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component SNF2_N PF00176.18 AAS53055.1 - 7.2e-86 287.6 0.5 7.2e-86 287.6 0.3 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AAS53055.1 - 2.7e-20 72.0 0.0 6.8e-17 61.0 0.0 3.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Bromodomain PF00439.20 AAS53055.1 - 5.2e-17 61.5 0.1 1.6e-16 59.9 0.1 1.9 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 AAS53055.1 - 1.3e-14 54.0 1.1 1.3e-14 54.0 0.7 4.1 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.10 AAS53055.1 - 4.1e-08 33.2 4.4 1e-07 32.0 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSA PF07529.8 AAS53055.1 - 0.00071 19.3 11.5 0.00071 19.3 8.0 2.8 2 0 0 2 2 2 1 HSA SRP-alpha_N PF04086.8 AAS53056.2 - 1.3 8.3 9.1 1.9 7.8 6.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Caudo_TAP PF02413.12 AAS53056.2 - 2.2 8.4 9.5 5 7.3 6.6 1.6 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein ANP PF00212.13 AAS53056.2 - 4.5 7.4 5.9 0.68 10.0 0.6 2.3 2 0 0 2 2 2 0 Atrial natriuretic peptide SURF1 PF02104.10 AAS53056.2 - 8 6.2 9.4 6.7 6.4 5.8 1.3 1 1 0 1 1 1 0 SURF1 family MMS19_N PF14500.1 AAS53057.2 - 2e-94 315.7 3.4 8.9e-91 303.7 0.0 3.3 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 AAS53057.2 - 3.9e-94 315.7 11.3 3.9e-94 315.7 7.9 1.7 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 AAS53057.2 - 1.8e-05 24.9 2.6 0.028 14.6 0.1 4.7 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.17 AAS53057.2 - 0.0036 17.2 0.5 45 4.4 0.1 4.8 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 AAS53057.2 - 0.0062 16.9 11.8 3.4 8.2 0.0 6.6 5 1 2 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 AAS53057.2 - 0.0068 16.7 0.1 2.1 8.8 0.0 4.3 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 AAS53057.2 - 0.011 15.6 2.2 0.38 10.6 0.1 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF2435) TyeA PF09059.5 AAS53057.2 - 0.023 14.6 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 TyeA TAFH PF07531.9 AAS53057.2 - 0.7 9.5 4.1 22 4.7 0.0 4.0 5 0 0 5 5 5 0 NHR1 homology to TAF MOR2-PAG1_N PF14222.1 AAS53058.2 - 3e-190 633.5 14.7 7e-190 632.3 10.2 1.7 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 AAS53058.2 - 2.9e-94 315.6 2.5 1.2e-93 313.6 0.8 2.7 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 AAS53058.2 - 3.5e-22 77.9 16.3 4.1e-13 47.9 0.5 3.3 3 0 0 3 3 3 3 Cell morphogenesis central region ApoO PF09769.4 AAS53059.1 - 5.1e-05 23.0 0.1 0.0038 16.9 0.0 2.2 2 0 0 2 2 2 2 Apolipoprotein O Aa_trans PF01490.13 AAS53060.2 - 1.4e-94 316.8 33.6 1.7e-94 316.6 23.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein COX2-transmemb PF09125.5 AAS53060.2 - 0.72 9.4 6.5 0.27 10.8 1.4 2.5 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane DNA_pol_B PF00136.16 AAS53061.1 - 7.3e-116 387.6 1.6 1.2e-115 387.0 1.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 AAS53061.1 - 3e-68 228.8 0.2 5.9e-68 227.9 0.1 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 AAS53061.1 - 6.3e-48 163.3 0.0 1.2e-47 162.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 AAS53061.1 - 2.3e-19 68.9 5.4 8.4e-19 67.1 3.7 2.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal zinc_ribbon_4 PF13717.1 AAS53061.1 - 0.00029 20.4 2.5 0.033 13.8 0.1 2.7 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AAS53061.1 - 0.0012 18.3 3.8 0.056 13.0 0.4 2.7 2 0 0 2 2 2 2 zinc-ribbon domain zf-RING-like PF08746.6 AAS53061.1 - 2.1 8.3 6.9 7 6.7 0.1 3.7 4 0 0 4 4 4 0 RING-like domain HSP20 PF00011.16 AAS53062.1 - 4.3e-13 49.0 0.0 5.3e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Motile_Sperm PF00635.21 AAS53062.1 - 0.071 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Fasciclin PF02469.17 AAS53063.2 - 8.4e-07 29.0 0.0 1.9e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain HLH PF00010.21 AAS53064.2 - 6.5e-20 70.5 0.7 1.3e-19 69.5 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2723 PF11028.3 AAS53064.2 - 0.0069 15.8 0.1 0.016 14.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2723) Sugar_tr PF00083.19 AAS53065.1 - 1.9e-47 161.8 31.7 2.7e-46 158.0 22.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AAS53065.1 - 2.2e-13 49.6 44.9 1.4e-06 27.2 15.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 AAS53065.1 - 5.2e-06 25.4 5.9 3.7e-05 22.6 4.1 2.3 1 1 0 1 1 1 1 BT1 family MFS_2 PF13347.1 AAS53065.1 - 0.00053 18.5 25.4 0.081 11.3 0.0 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein DUF606 PF04657.8 AAS53065.1 - 1.4 8.9 21.8 0.031 14.3 3.1 3.9 3 1 0 3 3 3 0 Protein of unknown function, DUF606 XPG_N PF00752.12 AAS53066.2 - 6.8e-24 84.0 0.0 1.5e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 AAS53066.2 - 3.1e-21 75.2 0.0 8.2e-21 73.8 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 AAS53066.2 - 0.03 14.5 0.0 0.082 13.1 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Ank_2 PF12796.2 AAS53067.1 - 1.5e-67 223.9 0.3 3.2e-18 65.8 0.0 3.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 AAS53067.1 - 1.6e-40 134.8 1.9 2.7e-08 33.2 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 AAS53067.1 - 5.9e-32 108.9 2.1 1.5e-10 40.9 0.0 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 AAS53067.1 - 4e-28 94.6 0.5 7.8e-06 25.6 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 AAS53067.1 - 9.2e-27 92.9 3.4 3.8e-10 40.0 0.0 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) zf-DHHC PF01529.15 AAS53067.1 - 4.3e-24 84.8 4.1 4.3e-24 84.8 2.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase HIG_1_N PF04588.8 AAS53067.1 - 0.075 12.7 0.8 0.19 11.4 0.6 1.6 1 0 0 1 1 1 0 Hypoxia induced protein conserved region DUF106 PF01956.11 AAS53067.1 - 0.089 12.3 0.8 0.19 11.2 0.6 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF2207 PF09972.4 AAS53067.1 - 0.58 8.6 2.3 1.2 7.6 1.6 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Claudin_2 PF13903.1 AAS53067.1 - 8.7 6.0 14.0 11 5.6 5.3 3.2 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction UNC45-central PF11701.3 AAS53068.2 - 6.8e-26 90.7 0.4 6.8e-26 90.7 0.3 3.4 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central Pex2_Pex12 PF04757.9 AAS53069.1 - 2.8e-34 118.5 5.5 3.9e-34 118.0 3.8 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 AAS53069.1 - 1.4e-09 37.5 16.2 2.2e-09 36.9 11.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AAS53069.1 - 1e-08 35.0 16.4 1.7e-08 34.3 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AAS53069.1 - 6.1e-08 32.2 18.3 8.8e-08 31.7 12.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AAS53069.1 - 3.4e-06 26.6 15.5 5.5e-06 25.9 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AAS53069.1 - 1.3e-05 24.7 13.0 2.4e-05 23.9 9.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AAS53069.1 - 0.00044 20.0 16.0 0.00086 19.1 11.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 AAS53069.1 - 0.00063 19.3 4.4 0.00063 19.3 3.1 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 AAS53069.1 - 0.0015 18.5 10.7 0.0028 17.7 7.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 AAS53069.1 - 1.8 8.1 10.5 3.4 7.2 7.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.1 AAS53070.1 - 2e-08 33.7 7.6 2e-08 33.7 5.3 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS53070.1 - 0.00085 19.3 9.0 0.00085 19.3 6.2 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AAS53070.1 - 0.013 15.1 9.4 0.013 15.1 6.5 3.9 4 0 0 4 4 4 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AAS53070.1 - 1.8 8.4 7.6 6.7 6.6 5.3 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 AAS53070.1 - 5.3 6.7 24.5 0.032 13.8 6.5 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PGP_phosphatase PF09419.5 AAS53071.1 - 2.1e-71 238.7 0.0 2.4e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase PF00702.21 AAS53071.1 - 6.8e-07 29.9 0.1 9.4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AAS53071.1 - 8.7e-07 28.5 0.0 1.8e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like Glyco_trans_1_4 PF13692.1 AAS53071.1 - 0.088 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 FAT PF02259.18 AAS53072.2 - 1.5e-70 237.9 9.0 1.5e-70 237.9 6.2 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 AAS53072.2 - 5e-42 143.9 2.2 1.7e-41 142.2 0.3 2.9 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 AAS53072.2 - 2e-07 30.3 0.1 6.1e-07 28.7 0.0 1.9 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 AAS53072.2 - 0.0062 16.1 4.6 0.078 12.6 0.1 3.2 3 1 0 3 3 3 1 TPR repeat TPR_12 PF13424.1 AAS53072.2 - 0.057 13.3 2.7 0.93 9.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_1 PF00133.17 AAS53073.2 - 7.4e-234 777.2 0.6 5.9e-233 774.2 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AAS53073.2 - 5.5e-28 97.6 0.2 1.5e-27 96.2 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AAS53073.2 - 1.5e-19 69.9 2.9 1.7e-07 30.2 0.4 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 AAS53073.2 - 0.00033 19.8 0.0 0.0027 16.8 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Atg8 PF02991.11 AAS53075.1 - 9.3e-48 160.5 0.1 1.1e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 AAS53075.1 - 1.2e-07 31.8 0.0 1.5e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Nucleoporin_C PF03177.9 AAS53076.1 - 6.5e-139 464.1 9.2 8.8e-139 463.7 6.4 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 AAS53076.1 - 1.7e-119 399.3 10.5 2.7e-119 398.6 7.3 1.3 1 0 0 1 1 1 1 Nup133 N terminal like DUF2240 PF09999.4 AAS53076.1 - 0.075 12.4 0.5 0.65 9.4 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2240) F-box-like PF12937.2 AAS53077.1 - 1.9e-05 24.3 0.1 5.7e-05 22.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AAS53077.1 - 0.018 14.6 0.0 0.069 12.8 0.0 2.1 1 0 0 1 1 1 0 F-box domain AT_hook PF02178.14 AAS53078.2 - 9.9 6.2 73.9 0.044 13.4 0.5 7.8 7 0 0 7 7 7 0 AT hook motif eIF-5_eIF-2B PF01873.12 AAS53079.2 - 5.9e-41 139.0 0.0 1e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 AAS53079.2 - 2.6e-26 91.3 0.1 8.6e-26 89.7 0.0 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Aldo_ket_red PF00248.16 AAS53080.1 - 1.9e-54 184.4 0.0 2.3e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family BRCT PF00533.21 AAS53081.1 - 9.8e-07 28.8 0.0 1.6e-05 24.9 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain FHA PF00498.21 AAS53081.1 - 0.002 18.2 0.0 0.0054 16.8 0.0 1.8 1 0 0 1 1 1 1 FHA domain Bac_surface_Ag PF01103.18 AAS53082.2 - 1.8e-22 80.2 0.2 2.3e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 Surface antigen Hph PF13694.1 AAS53082.2 - 0.0025 17.8 0.1 0.031 14.3 0.0 2.2 2 0 0 2 2 2 1 Sec63/Sec62 complex-interacting family RAI1 PF08652.6 AAS53083.2 - 7.7e-09 35.2 0.0 5.1e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease AA_permease PF00324.16 AAS53084.2 - 3.6e-110 368.5 31.4 4.1e-110 368.3 21.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS53084.2 - 4.3e-36 124.3 33.8 5.4e-36 124.0 23.5 1.1 1 0 0 1 1 1 1 Amino acid permease Cpn60_TCP1 PF00118.19 AAS53085.1 - 0.00038 19.2 0.0 0.0014 17.3 0.0 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family PRK PF00485.13 AAS53086.1 - 2.8e-12 46.6 0.1 6.7e-12 45.3 0.0 1.6 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family Carbpep_Y_N PF05388.6 AAS53086.1 - 0.03 14.4 0.0 0.27 11.4 0.0 2.3 3 0 0 3 3 3 0 Carboxypeptidase Y pro-peptide Cytidylate_kin2 PF13189.1 AAS53086.1 - 0.16 11.9 0.9 5.1 6.9 0.3 2.1 1 1 1 2 2 2 0 Cytidylate kinase-like family DEAD PF00270.24 AAS53087.2 - 1.4e-42 145.0 4.0 2.8e-42 144.0 1.8 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS53087.2 - 9.3e-28 95.9 0.2 6.8e-27 93.1 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 AAS53087.2 - 3.9e-05 23.3 0.3 8e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 AAS53087.2 - 0.00058 20.0 0.3 0.0023 18.0 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 AAS53087.2 - 0.006 16.1 0.6 0.02 14.4 0.4 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 AAS53087.2 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 AAS53087.2 - 0.05 13.3 0.1 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 AAS53087.2 - 0.062 12.9 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 Helicase PhoH PF02562.11 AAS53087.2 - 1.3 8.2 5.1 2.4 7.3 2.0 2.4 2 1 0 2 2 2 0 PhoH-like protein Atg31 PF09795.4 AAS53088.1 - 1.5e-49 167.8 5.8 2.6e-49 166.9 4.0 1.4 1 1 0 1 1 1 1 Autophagy-related protein 31 Tox-REase-7 PF15649.1 AAS53088.1 - 0.0066 16.5 0.1 0.025 14.7 0.1 1.9 1 1 1 2 2 2 1 Restriction endonuclease fold toxin 7 DUF3221 PF11518.3 AAS53088.1 - 0.08 12.6 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) DNA_topoisoIV PF00521.15 AAS53089.1 - 1.1e-121 406.7 1.7 2.2e-121 405.7 0.0 2.1 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 AAS53089.1 - 3.6e-34 117.4 2.0 7.5e-34 116.4 1.4 1.5 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 AAS53089.1 - 1.1e-12 47.7 0.0 5.6e-12 45.5 0.0 2.3 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 AAS53089.1 - 3.5e-09 36.3 0.0 7.4e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase C2 PF00168.25 AAS53090.1 - 7.1e-48 160.3 2.2 1.6e-20 72.6 0.1 4.6 4 0 0 4 4 4 4 C2 domain Tmemb_cc2 PF10267.4 AAS53091.1 - 8.4e-05 21.3 1.5 8.8e-05 21.2 1.1 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Dsl1_N PF11988.3 AAS53091.1 - 0.0029 16.5 1.4 0.0033 16.3 1.0 1.1 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 N terminal Snapin_Pallidin PF14712.1 AAS53091.1 - 0.0036 17.5 1.8 0.0044 17.3 1.2 1.1 1 0 0 1 1 1 1 Snapin/Pallidin Med28 PF11594.3 AAS53091.1 - 0.014 15.6 2.4 0.017 15.3 1.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 28 HOOK PF05622.7 AAS53091.1 - 0.024 12.4 2.9 0.028 12.2 2.0 1.0 1 0 0 1 1 1 0 HOOK protein DUF964 PF06133.6 AAS53091.1 - 0.031 14.2 2.2 0.039 13.9 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF964) DUF972 PF06156.8 AAS53091.1 - 0.034 14.5 0.6 0.039 14.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3482 PF11981.3 AAS53091.1 - 0.036 13.3 0.5 0.043 13.0 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) CR6_interact PF10147.4 AAS53091.1 - 0.053 12.8 1.2 0.061 12.6 0.9 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 COG2 PF06148.6 AAS53091.1 - 0.064 13.1 2.7 0.08 12.8 1.9 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 HlyD PF00529.15 AAS53091.1 - 0.075 12.3 0.6 0.085 12.1 0.4 1.0 1 0 0 1 1 1 0 HlyD family secretion protein DUF4164 PF13747.1 AAS53091.1 - 0.093 12.8 3.5 0.12 12.4 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.7 AAS53091.1 - 0.17 12.1 0.7 1.3 9.2 0.4 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Erp_C PF06780.6 AAS53091.1 - 0.21 11.4 1.6 0.26 11.1 1.1 1.1 1 0 0 1 1 1 0 Erp protein C-terminus IncA PF04156.9 AAS53091.1 - 0.22 11.0 4.3 0.29 10.6 3.0 1.1 1 0 0 1 1 1 0 IncA protein OST3_OST6 PF04756.8 AAS53092.2 - 1.5e-17 63.6 5.8 2.8e-17 62.7 4.0 1.5 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 AAS53092.2 - 0.00013 21.6 0.0 0.00026 20.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin Caa3_CtaG PF09678.5 AAS53092.2 - 0.0017 17.3 0.6 0.0017 17.3 0.4 2.0 2 0 0 2 2 2 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Thioredoxin_6 PF13848.1 AAS53092.2 - 0.053 13.3 0.0 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain MKT1_C PF12246.3 AAS53093.2 - 2.5e-72 242.8 3.0 3.5e-72 242.3 2.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 AAS53093.2 - 1.9e-32 111.3 0.2 4.8e-32 110.1 0.1 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 AAS53093.2 - 6.9e-20 71.2 0.0 2.8e-19 69.2 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 AAS53093.2 - 6.5e-10 38.9 0.0 1.5e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region SprB PF13573.1 AAS53093.2 - 0.12 11.9 0.1 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 SprB repeat Cpn60_TCP1 PF00118.19 AAS53094.1 - 1.6e-138 462.4 11.5 1.8e-138 462.1 8.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Transposase_23 PF03017.9 AAS53094.1 - 0.051 13.0 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 TNP1/EN/SPM transposase EF-hand_4 PF12763.2 AAS53095.2 - 7.5e-52 173.4 0.0 1.9e-50 168.8 0.1 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 AAS53095.2 - 1.5e-48 165.0 3.0 3.9e-48 163.6 2.1 1.6 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.27 AAS53095.2 - 0.0001 21.3 0.3 0.00029 19.9 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 AAS53095.2 - 0.0026 17.3 0.4 0.0059 16.2 0.3 1.6 1 0 0 1 1 1 1 EF-hand domain pair FlxA PF14282.1 AAS53095.2 - 0.0047 16.8 11.5 0.36 10.7 0.3 2.3 2 0 0 2 2 2 2 FlxA-like protein Phage_lysis PF03245.8 AAS53095.2 - 0.0047 16.9 1.4 0.12 12.3 0.0 2.9 3 0 0 3 3 3 1 Bacteriophage Rz lysis protein IncA PF04156.9 AAS53095.2 - 0.02 14.4 11.4 0.066 12.8 7.9 1.8 1 1 0 1 1 1 0 IncA protein EF-hand_6 PF13405.1 AAS53095.2 - 0.034 14.0 0.0 0.31 11.0 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.1 AAS53095.2 - 0.041 13.2 0.2 0.041 13.2 0.1 2.1 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.1 AAS53095.2 - 0.061 13.4 0.0 0.22 11.7 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair DivIC PF04977.10 AAS53095.2 - 0.19 11.2 1.0 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.6 AAS53095.2 - 0.31 10.7 2.7 5.7 6.6 0.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Wbp11 PF09429.5 AAS53095.2 - 0.33 10.9 3.9 2.1 8.3 0.1 2.4 1 1 1 2 2 2 0 WW domain binding protein 11 ATG16 PF08614.6 AAS53095.2 - 0.55 10.0 9.8 4.1 7.1 6.8 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) SlyX PF04102.7 AAS53095.2 - 1 9.7 7.6 2.7 8.4 0.2 2.7 2 0 0 2 2 2 0 SlyX Adeno_PIX PF03955.9 AAS53095.2 - 1.6 9.2 5.7 2.9 8.4 0.5 2.5 1 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) SKG6 PF08693.5 AAS53096.1 - 2.6e-16 58.6 1.3 6.6e-16 57.3 0.9 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain He_PIG PF05345.7 AAS53096.1 - 3.2e-10 39.8 4.0 4.1e-07 29.9 0.1 5.1 5 0 0 5 5 5 1 Putative Ig domain Rifin_STEVOR PF02009.11 AAS53096.1 - 3.7e-05 23.5 0.0 6.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 AAS53096.1 - 7.4e-05 22.4 0.9 0.00017 21.3 0.6 1.6 1 0 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.7 AAS53096.1 - 0.00035 20.0 0.3 0.00091 18.6 0.2 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor gpUL132 PF11359.3 AAS53096.1 - 0.00051 19.4 3.1 0.0012 18.2 2.2 1.6 1 0 0 1 1 1 1 Glycoprotein UL132 Sarcoglycan_2 PF05510.8 AAS53096.1 - 0.0038 15.5 0.1 0.36 9.0 0.0 3.0 3 0 0 3 3 3 1 Sarcoglycan alpha/epsilon DUF1180 PF06679.7 AAS53096.1 - 0.0063 16.4 1.5 0.019 14.8 1.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Herpes_gE PF02480.11 AAS53096.1 - 0.017 13.3 0.0 0.029 12.6 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 AAS53096.1 - 0.036 13.7 0.2 0.036 13.7 0.1 1.7 2 0 0 2 2 1 0 Syndecan domain DUF2207 PF09972.4 AAS53096.1 - 0.041 12.4 0.0 0.064 11.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.1 AAS53096.1 - 0.056 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mucin PF01456.12 AAS53096.1 - 7.4 6.3 22.5 0.017 14.8 7.5 2.5 3 0 0 3 3 3 0 Mucin-like glycoprotein 4HBT PF03061.17 AAS53097.1 - 3e-07 30.4 0.6 0.0067 16.5 0.1 2.6 2 0 0 2 2 2 2 Thioesterase superfamily SDH_beta PF03315.10 AAS53097.1 - 0.015 15.3 0.0 0.081 12.9 0.0 2.0 2 0 0 2 2 2 0 Serine dehydratase beta chain Mito_carr PF00153.22 AAS53098.1 - 8.1e-62 204.9 0.2 2.5e-21 75.1 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 AAS53098.1 - 1.3e-13 50.8 0.3 3.1e-09 36.8 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 AAS53098.1 - 1.6e-12 46.1 0.2 0.0095 15.7 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 AAS53098.1 - 1.7e-10 39.3 0.0 0.095 12.0 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.1 AAS53098.1 - 2e-07 30.0 0.5 0.18 11.2 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 AAS53098.1 - 1.6e-06 27.6 0.0 0.13 11.8 0.0 4.3 4 0 0 4 4 4 2 EF-hand domain pair HORMA PF02301.13 AAS53099.1 - 6.9e-18 64.8 0.0 8.9e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 HORMA domain DNA_mis_repair PF01119.14 AAS53100.1 - 1.1e-24 86.1 0.0 3.4e-24 84.5 0.0 1.9 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 AAS53100.1 - 7.8e-24 83.9 1.7 1.5e-23 82.9 0.0 2.3 3 0 0 3 3 3 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 AAS53100.1 - 1.7e-13 50.4 0.7 3.9e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AAS53100.1 - 9.8e-09 34.9 0.1 3.3e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S13 PF00416.17 AAS53101.1 - 5.7e-21 74.9 0.0 7.9e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S13/S18 EOS1 PF12326.3 AAS53102.1 - 1.7e-68 228.9 10.7 3.5e-68 227.9 7.4 1.5 1 0 0 1 1 1 1 N-glycosylation protein Tropomyosin_1 PF12718.2 AAS53103.3 - 1.9e-44 150.9 43.4 2.2e-44 150.7 30.1 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 AAS53103.3 - 1.7e-06 27.3 39.4 0.00037 19.6 9.5 1.8 1 1 1 2 2 2 2 Tropomyosin ATG16 PF08614.6 AAS53103.3 - 8.5e-05 22.4 37.7 0.019 14.8 10.8 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) MscS_porin PF12795.2 AAS53103.3 - 0.00013 21.4 23.2 0.00013 21.4 16.1 2.0 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain ADIP PF11559.3 AAS53103.3 - 0.00014 21.7 36.9 0.085 12.7 1.1 2.7 1 1 2 3 3 3 3 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 AAS53103.3 - 0.00031 20.6 43.9 0.0005 19.9 4.8 2.5 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.8 AAS53103.3 - 0.00044 20.1 22.9 0.00044 20.1 15.9 2.2 1 1 1 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Myosin_tail_1 PF01576.14 AAS53103.3 - 0.00051 17.9 38.5 0.00095 17.0 26.7 1.4 1 1 0 1 1 1 1 Myosin tail TMF_DNA_bd PF12329.3 AAS53103.3 - 0.00053 19.7 47.5 0.0052 16.5 15.5 3.2 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding GAS PF13851.1 AAS53103.3 - 0.00075 18.7 39.6 0.0038 16.4 27.5 2.1 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 AAS53103.3 - 0.0014 18.4 23.3 0.021 14.5 7.7 2.2 1 1 1 2 2 2 2 Laminin Domain II TBPIP PF07106.8 AAS53103.3 - 0.0027 17.2 36.6 0.07 12.6 13.9 2.2 1 1 1 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.16 AAS53103.3 - 0.003 17.4 41.3 0.055 13.4 1.0 4.4 1 1 3 4 4 4 2 bZIP transcription factor TMF_TATA_bd PF12325.3 AAS53103.3 - 0.0032 17.1 38.4 0.022 14.4 14.7 3.0 1 1 2 3 3 3 2 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.4 AAS53103.3 - 0.0034 17.4 28.9 0.24 11.5 5.6 3.1 1 1 2 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4201 PF13870.1 AAS53103.3 - 0.0052 16.2 34.6 0.054 12.9 18.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) Prefoldin_2 PF01920.15 AAS53103.3 - 0.0053 16.4 44.2 0.029 14.1 1.7 4.0 1 1 3 4 4 4 2 Prefoldin subunit DUF3287 PF11690.3 AAS53103.3 - 0.008 16.2 4.3 0.008 16.2 3.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3287) PspA_IM30 PF04012.7 AAS53103.3 - 0.013 14.8 28.0 0.45 9.8 11.5 2.1 1 1 1 2 2 2 0 PspA/IM30 family IncA PF04156.9 AAS53103.3 - 0.014 14.9 42.3 0.16 11.5 13.2 2.1 1 1 1 2 2 2 0 IncA protein MbeD_MobD PF04899.7 AAS53103.3 - 0.014 15.2 14.0 0.14 12.0 1.2 3.1 1 1 2 3 3 3 0 MbeD/MobD like KLRAQ PF10205.4 AAS53103.3 - 0.014 15.3 27.7 0.83 9.7 9.9 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein WXG100 PF06013.7 AAS53103.3 - 0.018 15.0 15.2 2.6 8.1 3.5 4.0 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF904 PF06005.7 AAS53103.3 - 0.019 15.2 48.9 0.8 10.0 1.9 4.1 2 1 0 2 2 1 0 Protein of unknown function (DUF904) APG6 PF04111.7 AAS53103.3 - 0.023 13.7 41.8 0.35 9.8 17.4 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 AAA_13 PF13166.1 AAS53103.3 - 0.034 12.6 30.6 0.079 11.4 21.2 1.6 1 1 0 1 1 1 0 AAA domain DUF3450 PF11932.3 AAS53103.3 - 0.036 13.3 27.6 0.019 14.2 9.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Vps5 PF09325.5 AAS53103.3 - 0.038 13.2 0.8 0.038 13.2 0.5 3.3 1 1 2 3 3 3 0 Vps5 C terminal like Lectin_N PF03954.9 AAS53103.3 - 0.05 13.0 17.0 0.043 13.2 5.6 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Spectrin PF00435.16 AAS53103.3 - 0.086 13.1 31.3 0.89 9.8 8.8 3.1 1 1 2 3 3 3 0 Spectrin repeat Spc24 PF08286.6 AAS53103.3 - 0.089 12.4 37.5 0.19 11.4 0.7 4.0 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 ERM PF00769.14 AAS53103.3 - 0.094 12.2 39.2 0.9 9.0 11.2 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family EzrA PF06160.7 AAS53103.3 - 0.095 10.8 31.9 0.054 11.6 8.5 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Filament PF00038.16 AAS53103.3 - 0.095 12.1 32.4 0.28 10.5 8.0 2.0 1 1 1 2 2 2 0 Intermediate filament protein FlaC_arch PF05377.6 AAS53103.3 - 0.095 12.6 26.6 2.5 8.0 0.1 4.7 2 2 3 5 5 5 0 Flagella accessory protein C (FlaC) IFT57 PF10498.4 AAS53103.3 - 0.11 11.1 31.3 0.82 8.3 7.5 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Reo_sigmaC PF04582.7 AAS53103.3 - 0.14 11.3 9.2 0.36 9.9 1.6 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TelA PF05816.6 AAS53103.3 - 0.14 10.8 22.9 0.024 13.3 2.5 2.1 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) Nup54 PF13874.1 AAS53103.3 - 0.16 11.6 24.9 0.07 12.7 8.5 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Ax_dynein_light PF10211.4 AAS53103.3 - 0.18 11.5 35.4 0.44 10.3 1.9 2.9 1 1 2 3 3 3 0 Axonemal dynein light chain DUF1664 PF07889.7 AAS53103.3 - 0.18 11.5 20.0 0.14 11.9 4.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 AAS53103.3 - 0.19 12.0 31.9 1.5e+04 -4.2 22.1 3.1 1 1 0 1 1 0 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 AAS53103.3 - 0.22 11.3 35.4 0.3 10.9 3.3 4.7 2 1 2 4 4 4 0 Basic region leucine zipper Phage_GP20 PF06810.6 AAS53103.3 - 0.23 10.9 37.4 0.3 10.5 10.1 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 FliD_C PF07195.7 AAS53103.3 - 0.26 10.5 21.1 0.21 10.8 1.0 3.1 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus TPR_MLP1_2 PF07926.7 AAS53103.3 - 0.27 10.9 43.8 0.22 11.2 11.4 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HOOK PF05622.7 AAS53103.3 - 0.3 8.8 33.3 0.34 8.6 23.1 1.0 1 0 0 1 1 1 0 HOOK protein DUF4200 PF13863.1 AAS53103.3 - 0.32 10.9 42.1 0.41 10.5 4.8 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Fzo_mitofusin PF04799.8 AAS53103.3 - 0.48 9.7 23.0 1.1 8.6 5.4 2.7 1 1 1 2 2 2 0 fzo-like conserved region Rab5-bind PF09311.6 AAS53103.3 - 0.51 10.2 37.4 5.7 6.7 25.9 2.3 1 1 0 1 1 1 0 Rabaptin-like protein Atg14 PF10186.4 AAS53103.3 - 0.53 9.1 30.2 0.45 9.4 9.1 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3584 PF12128.3 AAS53103.3 - 0.59 7.3 30.6 0.79 6.9 21.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NDUFB10 PF10249.4 AAS53103.3 - 0.67 10.1 6.3 5.7 7.0 0.1 2.8 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase subunit 10 MIS13 PF08202.6 AAS53103.3 - 0.68 8.9 29.7 7.4 5.5 5.4 2.2 1 1 1 2 2 2 0 Mis12-Mtw1 protein family TACC PF05010.9 AAS53103.3 - 0.84 9.3 28.7 0.49 10.1 0.8 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Fib_alpha PF08702.5 AAS53103.3 - 0.89 9.6 23.3 2.5 8.2 0.3 2.7 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Fumble PF03630.9 AAS53103.3 - 0.97 8.2 9.3 1.1 7.9 6.4 1.1 1 0 0 1 1 1 0 Fumble Moulting_cycle PF04870.11 AAS53103.3 - 1 8.3 19.1 0.55 9.2 11.8 1.4 1 1 0 1 1 1 0 Moulting cycle Mnd1 PF03962.10 AAS53103.3 - 1.1 8.9 34.9 16 5.0 9.9 2.4 1 1 1 2 2 2 0 Mnd1 family Lebercilin PF15619.1 AAS53103.3 - 1.1 8.6 39.1 2.9 7.2 27.1 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Sipho_Gp157 PF05565.6 AAS53103.3 - 1.1 8.8 26.3 0.63 9.6 5.9 2.2 1 1 0 2 2 2 0 Siphovirus Gp157 DivIC PF04977.10 AAS53103.3 - 1.1 8.7 37.8 4.9 6.7 2.0 4.2 1 1 3 4 4 4 0 Septum formation initiator PilJ PF13675.1 AAS53103.3 - 1.2 9.5 13.6 12 6.2 1.8 2.7 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Spc7 PF08317.6 AAS53103.3 - 1.2 7.7 35.1 6.4 5.3 24.4 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 AAS53103.3 - 1.6 8.8 32.9 4.4 7.3 0.5 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Rootletin PF15035.1 AAS53103.3 - 1.8 8.4 37.3 4.5 7.2 14.1 2.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion CCDC155 PF14662.1 AAS53103.3 - 2.2 7.8 39.3 3.7 7.1 19.5 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Rota_NSP3 PF01665.11 AAS53103.3 - 2.4 7.0 15.2 0.17 10.7 0.6 2.1 1 1 1 2 2 2 0 Rotavirus non-structural protein NSP3 Imm15 PF15590.1 AAS53103.3 - 2.4 7.2 7.2 5.7 6.0 0.3 2.9 3 0 0 3 3 3 0 Immunity protein 15 Snapin_Pallidin PF14712.1 AAS53103.3 - 2.8 8.3 25.3 1.1 9.6 4.8 3.2 1 1 2 3 3 3 0 Snapin/Pallidin Cortex-I_coil PF09304.5 AAS53103.3 - 2.9 7.9 34.5 4.9 7.2 10.5 2.7 1 1 2 3 3 3 0 Cortexillin I, coiled coil DivIVA PF05103.8 AAS53103.3 - 2.9 7.9 35.0 11 6.0 9.1 3.9 1 1 1 2 2 2 0 DivIVA protein TFR_dimer PF04253.10 AAS53103.3 - 3 7.4 10.0 3.7 7.1 0.8 3.1 1 1 2 3 3 3 0 Transferrin receptor-like dimerisation domain DUF3552 PF12072.3 AAS53103.3 - 3.1 6.9 40.8 3 6.9 13.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) TMCO5 PF14992.1 AAS53103.3 - 3.1 6.8 33.7 1.3 8.0 8.6 2.2 1 1 1 2 2 2 0 TMCO5 family Fmp27_WPPW PF10359.4 AAS53103.3 - 3.2 6.0 29.6 4.9 5.4 13.6 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain THOC7 PF05615.8 AAS53103.3 - 3.3 7.9 34.0 2.6 8.2 7.6 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 CALCOCO1 PF07888.6 AAS53103.3 - 3.5 5.7 28.9 4.9 5.3 20.1 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DegT_DnrJ_EryC1 PF01041.12 AAS53103.3 - 3.9 6.4 6.7 4.5 6.1 4.6 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Kinetocho_Slk19 PF12709.2 AAS53103.3 - 3.9 7.6 37.9 3.7 7.6 3.5 3.9 1 1 3 4 4 4 0 Central kinetochore-associated HalX PF08663.5 AAS53103.3 - 4 7.5 30.8 0.29 11.1 3.3 4.1 1 1 3 4 4 4 0 HalX domain DUF2959 PF11172.3 AAS53103.3 - 4.1 7.1 21.9 23 4.6 15.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2959) Striatin PF08232.7 AAS53103.3 - 4.9 7.4 28.3 1.3 9.3 0.7 2.4 1 1 1 2 2 2 0 Striatin family CRT10 PF08728.5 AAS53103.3 - 5 4.9 17.2 5.4 4.8 11.9 1.0 1 0 0 1 1 1 0 CRT10 Tweety PF04906.8 AAS53103.3 - 5.7 5.2 8.1 5.9 5.1 4.7 1.7 1 1 0 1 1 1 0 Tweety MAD PF05557.8 AAS53103.3 - 5.7 4.9 37.8 7.5 4.4 26.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein HlyD PF00529.15 AAS53103.3 - 5.7 6.1 16.7 10 5.3 11.6 1.5 1 1 0 1 1 1 0 HlyD family secretion protein DUF869 PF05911.6 AAS53103.3 - 6.2 4.9 34.7 13 3.8 24.1 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF4559 PF15112.1 AAS53103.3 - 6.5 5.8 24.3 6.5 5.8 16.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Sec2p PF06428.6 AAS53103.3 - 6.8 6.5 36.1 1.1 9.1 11.7 4.2 1 1 3 4 4 3 0 GDP/GTP exchange factor Sec2p DUF812 PF05667.6 AAS53103.3 - 6.9 5.0 31.9 43 2.4 22.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) GBP_C PF02841.9 AAS53103.3 - 7.5 5.6 30.3 9.4 5.3 21.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain OmpH PF03938.9 AAS53103.3 - 7.5 6.4 34.1 1.2 9.0 10.2 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Cauli_AT PF03233.8 AAS53103.3 - 8.1 6.1 22.5 7.1 6.3 6.1 2.5 1 1 1 2 2 2 0 Aphid transmission protein GrpE PF01025.14 AAS53103.3 - 8.1 5.9 35.5 1.5e+04 -15.6 24.6 3.5 1 1 0 1 1 0 0 GrpE DUF342 PF03961.8 AAS53103.3 - 8.2 4.7 33.1 4.7 5.5 7.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) CDC37_N PF03234.9 AAS53103.3 - 8.8 6.6 32.6 18 5.6 16.0 2.1 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding LLC1 PF14945.1 AAS53103.3 - 9.2 6.6 17.2 0.71 10.2 4.5 2.6 1 1 2 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Prominin PF05478.6 AAS53103.3 - 9.5 3.6 20.2 2.2 5.7 8.9 2.0 1 1 1 2 2 2 0 Prominin Peptidase_M1 PF01433.15 AAS53105.1 - 5.3e-81 272.6 0.0 1e-80 271.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 AAS53105.1 - 2.3e-48 165.1 0.1 3.4e-48 164.5 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 AAS53105.1 - 4.6e-17 62.2 0.1 1.3e-16 60.8 0.1 1.7 2 0 0 2 2 2 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 AAS53105.1 - 0.059 13.3 2.9 0.15 12.0 2.0 1.7 1 0 0 1 1 1 0 M61 glycyl aminopeptidase DnaJ PF00226.26 AAS53106.1 - 3.2e-21 74.8 0.3 6e-21 73.9 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AAS53106.1 - 3.9e-15 55.5 0.0 7.2e-14 51.4 0.0 2.6 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AAS53106.1 - 5.1e-08 32.8 20.3 1.5e-07 31.3 14.1 1.9 1 0 0 1 1 1 1 DnaJ central domain MscS_porin PF12795.2 AAS53107.1 - 0.0034 16.7 2.2 0.0064 15.8 1.5 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain TroA PF01297.12 AAS53107.1 - 0.03 13.5 0.2 0.049 12.8 0.2 1.3 1 0 0 1 1 1 0 Periplasmic solute binding protein family Rootletin PF15035.1 AAS53107.1 - 0.055 13.4 1.9 0.17 11.8 0.5 2.4 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Syntaxin-6_N PF09177.6 AAS53107.1 - 0.093 13.1 1.4 0.49 10.8 0.7 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Sec5 PF15469.1 AAS53107.1 - 0.23 11.1 0.4 0.46 10.1 0.3 1.5 1 1 0 1 1 1 0 Exocyst complex component Sec5 Apolipoprotein PF01442.13 AAS53107.1 - 0.85 9.0 5.5 3.4 7.1 3.8 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HSCB_C PF07743.8 AAS53107.1 - 2 8.9 6.2 0.25 11.8 0.4 2.5 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain DUF1752 PF08550.5 AAS53108.1 - 6.4e-11 41.6 0.3 1.3e-10 40.6 0.2 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Brix PF04427.13 AAS53109.2 - 1.2e-47 162.0 0.3 1.6e-47 161.6 0.2 1.1 1 0 0 1 1 1 1 Brix domain LSM PF01423.17 AAS53111.2 - 1.3e-16 59.9 0.0 2e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 LSM domain CHZ PF09649.5 AAS53112.1 - 7.5e-20 69.8 1.5 7.5e-20 69.8 1.0 2.7 2 0 0 2 2 2 1 Histone chaperone domain CHZ DUF572 PF04502.8 AAS53112.1 - 6.7 5.8 11.0 7.4 5.6 7.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ras PF00071.17 AAS53113.2 - 1.3e-60 203.4 0.4 1.6e-60 203.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS53113.2 - 1.2e-19 70.9 0.1 1.9e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS53113.2 - 2e-13 49.9 0.0 2.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 AAS53113.2 - 1.9e-07 31.0 0.1 3.5e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AAS53113.2 - 1e-05 25.0 0.1 3.1e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 AAS53113.2 - 0.00018 20.6 0.4 0.00023 20.3 0.3 1.4 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 AAS53113.2 - 0.00034 19.8 0.0 0.00042 19.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 AAS53113.2 - 0.00075 18.7 0.1 0.0018 17.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 AAS53113.2 - 0.0026 16.9 0.0 0.0042 16.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 AAS53113.2 - 0.0088 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 AAS53113.2 - 0.013 15.5 0.1 0.034 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 AAS53113.2 - 0.015 14.8 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 AAS53113.2 - 0.027 14.4 0.3 0.1 12.5 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain TraG_N PF07916.6 AAS53113.2 - 0.035 12.5 0.1 0.042 12.2 0.1 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Septin PF00735.13 AAS53113.2 - 0.059 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Septin SpoIIID PF12116.3 AAS53113.2 - 0.061 13.2 0.0 3.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D ABC_tran PF00005.22 AAS53113.2 - 0.084 13.1 0.7 0.13 12.5 0.4 1.6 1 1 0 1 1 1 0 ABC transporter DUF1128 PF06569.6 AAS53113.2 - 0.14 11.9 0.2 0.32 10.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) BicD PF09730.4 AAS53115.1 - 0.0094 14.3 0.2 0.017 13.4 0.2 1.4 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D ATP_bind_3 PF01171.15 AAS53116.1 - 4.3e-17 62.1 0.0 9e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 AAS53116.1 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 AAS53116.1 - 0.015 13.8 0.0 0.025 13.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DUF1639 PF07797.9 AAS53116.1 - 1 8.7 4.7 6.6 6.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) PX PF00787.19 AAS53117.2 - 2e-13 50.1 0.2 4.6e-13 48.9 0.2 1.6 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 AAS53117.2 - 1.4e-07 31.0 6.6 4.1e-07 29.5 4.6 1.8 1 0 0 1 1 1 1 SNARE domain WD40 PF00400.27 AAS53118.1 - 6e-15 54.4 23.2 2.3e-08 33.5 0.2 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat PKD PF00801.15 AAS53118.1 - 0.044 13.5 0.7 0.62 9.8 0.1 2.6 2 1 0 2 2 2 0 PKD domain Cyclin PF08613.6 AAS53119.1 - 1.4e-05 25.5 0.0 2.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin Kinesin PF00225.18 AAS53120.1 - 3.9e-112 374.2 0.1 6.1e-112 373.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain COX14 PF14880.1 AAS53122.1 - 1.3e-23 82.3 1.2 1.4e-23 82.2 0.9 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c assembly SHR3_chaperone PF08229.6 AAS53122.1 - 0.024 13.5 0.1 0.028 13.3 0.0 1.0 1 0 0 1 1 1 0 ER membrane protein SH3 DUF1772 PF08592.6 AAS53122.1 - 0.038 13.7 0.0 0.038 13.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) MFS_1 PF07690.11 AAS53123.1 - 9.6e-13 47.5 25.6 1.4e-12 47.0 17.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4500 PF14937.1 AAS53123.1 - 0.0052 16.5 2.9 0.38 10.6 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4500) Septin PF00735.13 AAS53124.1 - 9.5e-108 359.4 0.9 1e-107 359.3 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 AAS53124.1 - 1.5e-07 31.3 0.0 3.3e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AAS53124.1 - 3.1e-06 27.1 8.4 0.0023 17.7 0.2 3.1 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 AAS53124.1 - 7.2e-05 22.0 0.9 0.00052 19.2 0.6 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 AAS53124.1 - 0.0002 20.5 0.0 0.0002 20.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.22 AAS53124.1 - 0.0003 21.0 1.6 0.00058 20.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 AAS53124.1 - 0.0013 19.2 0.6 0.005 17.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein IIGP PF05049.8 AAS53124.1 - 0.0016 17.3 0.1 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_10 PF12846.2 AAS53124.1 - 0.019 14.4 0.5 0.03 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 AAS53124.1 - 0.033 14.5 5.2 0.068 13.4 1.6 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 AAS53124.1 - 0.058 13.1 0.1 0.14 11.9 0.0 1.8 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 AAS53124.1 - 0.06 13.4 0.1 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 AAS53124.1 - 0.094 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 AAS53124.1 - 0.1 12.0 1.5 1.4 8.4 0.1 2.5 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 AAS53124.1 - 0.15 11.9 1.2 0.89 9.4 0.1 2.6 2 1 1 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 AAS53124.1 - 0.18 11.2 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Gasdermin PF04598.7 AAS53124.1 - 0.23 10.1 8.9 0.36 9.5 4.9 1.8 1 1 1 2 2 2 0 Gasdermin family G-alpha PF00503.15 AAS53124.1 - 0.84 8.2 7.8 0.25 9.9 0.1 3.0 3 0 0 3 3 3 0 G-protein alpha subunit IGPS PF00218.16 AAS53125.1 - 4e-83 278.3 0.0 5.2e-83 277.9 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 AAS53125.1 - 7.3e-53 178.8 0.0 1e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AAS53125.1 - 1.2e-09 38.0 0.1 2.3e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 AAS53125.1 - 0.01 15.3 0.0 0.11 12.0 0.0 2.5 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 AAS53125.1 - 0.13 11.2 0.0 0.26 10.2 0.0 1.6 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Syja_N PF02383.13 AAS53126.1 - 9.9e-82 274.2 0.0 1.4e-81 273.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain PUL PF08324.6 AAS53127.2 - 1.6e-62 210.7 0.4 2.1e-62 210.3 0.3 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 AAS53127.2 - 1.3e-41 141.2 0.1 2.4e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 AAS53127.2 - 3.9e-39 131.1 17.5 8.8e-11 41.2 0.1 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 AAS53127.2 - 4e-05 23.3 0.1 0.93 9.2 0.0 4.0 2 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region FoP_duplication PF13865.1 AAS53128.2 - 5.8e-07 29.8 0.9 5.8e-07 29.8 0.6 2.3 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.17 AAS53128.2 - 0.003 17.1 0.0 0.0093 15.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS53128.2 - 0.044 13.7 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.22 AAS53129.1 - 8.3e-48 160.0 9.2 7.3e-20 70.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NMT1 PF09084.6 AAS53130.1 - 2e-75 253.0 0.0 2.6e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 AAS53130.1 - 2.1e-05 24.0 0.1 0.00067 19.1 0.1 2.6 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.2 AAS53130.1 - 0.00021 20.7 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.2 AAS53130.1 - 0.064 12.1 0.0 0.22 10.4 0.0 1.8 1 1 0 1 1 1 0 PBP superfamily domain Lipase_3 PF01764.20 AAS53131.1 - 5.8e-28 97.2 0.0 1e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) tify PF06200.9 AAS53131.1 - 0.034 13.3 0.0 0.072 12.3 0.0 1.6 1 0 0 1 1 1 0 tify domain Lipase_3 PF01764.20 AAS53132.1 - 1.4e-21 76.6 0.0 2.1e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase_3 PF01764.20 AAS53133.1 - 1.4e-29 102.4 0.0 2.2e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF3089 PF11288.3 AAS53133.1 - 0.032 13.3 0.1 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_5 PF12695.2 AAS53133.1 - 0.049 13.3 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 AAS53133.1 - 0.059 12.7 0.3 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) HMG_box PF00505.14 AAS53134.1 - 0.12 12.6 1.7 2.2 8.6 1.2 2.3 1 1 0 1 1 1 0 HMG (high mobility group) box Homeobox PF00046.24 AAS53135.2 - 2.3e-16 59.1 1.9 2.9e-16 58.8 1.3 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 AAS53135.2 - 1.5e-05 24.5 0.8 2.3e-05 23.9 0.2 1.5 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.1 AAS53135.2 - 0.18 11.5 0.6 0.4 10.3 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain SUI1 PF01253.17 AAS53136.1 - 7.9e-29 99.3 0.4 9.5e-29 99.0 0.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2575 PF10837.3 AAS53136.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) Cas_Csa5 PF09702.5 AAS53136.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) NAP PF00956.13 AAS53137.2 - 1.9e-14 53.3 2.3 1.3e-09 37.5 0.0 2.3 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) HSP20 PF00011.16 AAS53138.1 - 1.2e-19 70.0 0.5 1.5e-19 69.7 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family GvpH PF05455.6 AAS53138.1 - 0.022 14.3 0.2 0.93 9.1 0.0 2.0 1 1 1 2 2 2 0 GvpH BON PF04972.12 AAS53138.1 - 0.034 13.8 0.0 7.7 6.3 0.0 2.5 2 0 0 2 2 2 0 BON domain Mannosyl_trans3 PF11051.3 AAS53139.2 - 5.6e-65 219.3 0.1 8.3e-65 218.8 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 AAS53139.2 - 0.0036 16.6 1.1 0.0047 16.3 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 8 BRI3BP PF14965.1 AAS53140.1 - 2.1 7.6 15.9 0.11 11.8 2.4 2.1 2 0 0 2 2 2 0 Negative regulator of p53/TP53 SNARE PF05739.14 AAS53142.2 - 3.9e-18 64.8 3.7 3.9e-18 64.8 2.6 1.8 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 AAS53142.2 - 1.1e-07 31.7 13.3 6.3e-07 29.3 1.4 3.6 2 2 0 2 2 2 1 Syntaxin-like protein Synaptobrevin PF00957.16 AAS53142.2 - 0.00014 21.3 0.7 0.00027 20.4 0.5 1.5 1 0 0 1 1 1 1 Synaptobrevin LPP PF04728.8 AAS53142.2 - 0.0014 18.4 0.9 0.12 12.1 0.1 2.6 2 0 0 2 2 2 1 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.7 AAS53142.2 - 0.027 14.2 6.1 0.05 13.4 1.8 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 AAS53142.2 - 0.038 13.1 0.4 0.89 8.6 0.1 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF3708 PF12501.3 AAS53142.2 - 0.086 12.6 0.9 0.14 11.9 0.2 1.6 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter RmuC PF02646.11 AAS53142.2 - 0.092 11.5 3.2 0.085 11.6 1.1 1.7 2 0 0 2 2 2 0 RmuC family Noelin-1 PF12308.3 AAS53142.2 - 0.12 12.2 2.1 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Neurogenesis glycoprotein Spc7 PF08317.6 AAS53142.2 - 0.18 10.4 7.8 0.095 11.3 2.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 AAS53142.2 - 0.21 11.3 4.2 0.49 10.1 1.4 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF1978 PF09321.5 AAS53142.2 - 0.21 10.9 2.7 0.4 10.0 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) NPV_P10 PF05531.7 AAS53142.2 - 0.54 10.5 7.1 1.8 8.8 1.7 2.8 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.20 AAS53142.2 - 1.2 9.3 5.8 17 5.6 1.8 2.4 2 0 0 2 2 2 0 Syntaxin COMP PF11598.3 AAS53142.2 - 1.5 8.9 5.0 6.5 6.9 0.1 3.2 2 2 1 3 3 3 0 Cartilage oligomeric matrix protein FliJ PF02050.11 AAS53142.2 - 1.8 8.6 12.9 5.5 7.0 5.4 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein bZIP_2 PF07716.10 AAS53143.1 - 0.0057 16.4 7.2 0.016 14.9 5.0 1.8 1 0 0 1 1 1 1 Basic region leucine zipper Herpes_BLRF2 PF05812.7 AAS53143.1 - 0.031 14.0 6.1 0.056 13.2 1.1 2.4 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein Syntaxin PF00804.20 AAS53143.1 - 0.11 12.7 2.6 0.26 11.4 1.8 1.6 1 0 0 1 1 1 0 Syntaxin PspB PF06667.7 AAS53143.1 - 0.49 10.3 2.0 1 9.3 1.4 1.4 1 0 0 1 1 1 0 Phage shock protein B RGS PF00615.14 AAS53144.1 - 6.7e-14 52.0 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain HMGL-like PF00682.14 AAS53145.2 - 1.6e-73 247.2 0.1 7.5e-73 245.0 0.0 2.1 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.5 AAS53145.2 - 6.2e-24 84.2 0.0 1.2e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Syja_N PF02383.13 AAS53146.2 - 2.5e-94 315.6 0.7 3.7e-94 315.0 0.5 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 AAS53146.2 - 1e-26 94.3 0.0 2e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YEATS PF03366.11 AAS53147.1 - 1.2e-35 121.0 1.1 2e-35 120.3 0.8 1.4 1 0 0 1 1 1 1 YEATS family Osmo_CC PF08946.5 AAS53147.1 - 1.8 8.6 7.1 4.4 7.3 5.0 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil His_Phos_1 PF00300.17 AAS53148.1 - 1.5e-22 80.4 0.0 4.3e-22 78.9 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) TFIIIC_sub6 PF10419.4 AAS53148.1 - 5.8e-15 54.4 0.0 1.1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit Maf PF02545.9 AAS53149.1 - 8.8e-42 142.4 0.0 1.1e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein RRM_1 PF00076.17 AAS53150.1 - 2.3e-17 62.3 0.0 4e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS53150.1 - 3.7e-13 49.2 0.0 7.3e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS53150.1 - 3.7e-11 42.7 0.0 6.5e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AAS53150.1 - 0.013 15.2 0.0 0.036 13.8 0.0 1.8 1 1 0 1 1 1 0 Limkain b1 Cyt-b5 PF00173.23 AAS53151.1 - 4.5e-26 90.4 0.0 6.7e-26 89.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HEAT PF02985.17 AAS53152.1 - 2.6e-05 23.9 0.5 1.4 9.2 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat Vac14_Fab1_bd PF12755.2 AAS53152.1 - 0.00061 20.1 0.3 2.9 8.3 0.0 3.5 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 AAS53152.1 - 0.0037 16.6 0.1 0.0096 15.3 0.1 1.7 1 1 0 1 1 1 1 CLASP N terminal Cnd1 PF12717.2 AAS53152.1 - 0.0093 15.8 4.5 0.64 9.8 0.0 3.0 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 AAS53152.1 - 0.025 12.9 5.5 0.13 10.5 1.6 2.4 1 1 1 2 2 2 0 Adaptin N terminal region Cohesin_HEAT PF12765.2 AAS53152.1 - 0.13 12.2 1.0 23 5.0 0.0 3.9 3 1 1 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DEAD PF00270.24 AAS53153.2 - 3e-45 153.7 0.0 4e-44 150.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS53153.2 - 1.5e-29 101.6 0.2 9e-29 99.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS53153.2 - 0.00073 19.4 0.0 0.0018 18.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 AAS53153.2 - 0.017 13.5 0.2 0.24 9.7 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 AAS53153.2 - 0.076 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain RNA_pol_L_2 PF13656.1 AAS53154.2 - 3.4e-32 109.7 0.0 4.5e-32 109.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 AAS53154.2 - 3.7e-13 48.3 0.0 5.1e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain HMG_box PF00505.14 AAS53155.1 - 1.7e-32 111.4 1.9 9.1e-17 61.0 0.0 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 AAS53155.1 - 1.2e-20 73.6 0.1 3.6e-10 40.0 0.5 2.2 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.7 AAS53155.1 - 0.00038 20.0 0.3 0.043 13.5 0.0 2.9 3 0 0 3 3 3 1 CHDNT (NUC034) domain DUF1014 PF06244.7 AAS53155.1 - 0.0061 16.7 0.3 0.32 11.2 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1014) TrkH PF02386.11 AAS53156.2 - 5.3e-130 433.1 15.1 3.1e-129 430.5 6.4 2.1 2 0 0 2 2 2 2 Cation transport protein Pkinase PF00069.20 AAS53157.1 - 1.1e-54 185.3 0.0 1.5e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53157.1 - 1.9e-37 128.7 0.0 2.6e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS53157.1 - 0.00014 20.9 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 AAS53157.1 - 0.0018 17.2 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 AAS53157.1 - 0.3 9.8 0.0 0.44 9.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TAT_signal PF10518.4 AAS53158.1 - 0.019 14.9 0.2 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence zf-H2C2 PF09337.5 AAS53159.1 - 7.2e-21 73.3 5.0 1.3e-20 72.5 3.4 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 AAS53159.1 - 6.5e-05 22.8 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 AAS53159.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AAS53159.1 - 0.11 12.6 0.0 0.54 10.3 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GCD14 PF08704.5 AAS53160.1 - 2.3e-82 276.1 0.0 2.1e-81 273.0 0.0 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.15 AAS53160.1 - 0.00017 20.7 0.0 0.00055 19.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 AAS53160.1 - 0.0013 18.7 0.0 0.0023 17.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS53160.1 - 0.0016 19.0 0.0 0.0033 17.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Gcd10p PF04189.8 AAS53160.1 - 0.0053 15.9 0.1 0.015 14.4 0.0 1.7 2 0 0 2 2 2 1 Gcd10p family PCMT PF01135.14 AAS53160.1 - 0.024 14.1 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3748 PF12566.3 AAS53160.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) Acyl-CoA_dh_1 PF00441.19 AAS53161.1 - 6.7e-19 68.4 0.0 1.1e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 AAS53161.1 - 6.5e-10 38.3 0.1 1.2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 AAS53161.1 - 0.00067 20.2 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain LSM PF01423.17 AAS53162.1 - 1.1e-13 50.5 0.1 1.7e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain PUF PF00806.14 AAS53162.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat DUF1687 PF07955.6 AAS53163.1 - 3e-34 117.8 0.0 3.4e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) DUF2413 PF10310.4 AAS53164.2 - 2.2e-118 395.9 1.6 2.4e-118 395.7 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Alb1 PF09135.6 AAS53165.1 - 9.6e-20 71.2 5.5 9.6e-20 71.2 3.8 1.4 2 0 0 2 2 2 1 Alb1 Ribul_P_3_epim PF00834.14 AAS53166.1 - 1.8e-69 232.8 0.0 2.3e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PcrB PF01884.12 AAS53166.1 - 0.015 14.6 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 PcrB family QRPTase_C PF01729.14 AAS53166.1 - 0.084 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.19 AAS53166.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Sugar_tr PF00083.19 AAS53167.1 - 3.1e-171 569.9 29.2 3.5e-171 569.7 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AAS53167.1 - 1.1e-35 123.0 38.8 6e-29 100.8 9.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.6 AAS53167.1 - 0.46 10.2 0.0 0.46 10.2 0.0 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF1772) tRNA-synt_1d PF00750.14 AAS53168.1 - 5.8e-104 347.7 4.8 7.1e-104 347.4 3.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 AAS53168.1 - 6.8e-30 103.4 0.3 2.3e-28 98.5 0.0 2.6 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 AAS53168.1 - 2.2e-05 24.8 0.0 8.7e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain VD10_N PF08476.5 AAS53168.1 - 0.079 12.4 0.1 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Viral D10 N-terminal Sugar_tr PF00083.19 AAS53169.1 - 7e-173 575.3 27.1 8e-173 575.1 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AAS53169.1 - 6.4e-31 107.3 25.4 8.6e-30 103.6 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytochrom_B558a PF05038.8 AAS53169.1 - 0.011 15.3 2.0 0.098 12.2 0.3 2.5 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit DUF2178 PF09946.4 AAS53169.1 - 3.2 7.5 7.9 8.3 6.1 1.1 3.8 3 1 1 4 4 4 0 Predicted membrane protein (DUF2178) Sugar_tr PF00083.19 AAS53170.1 - 6.7e-162 539.1 28.2 7.6e-162 538.9 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AAS53170.1 - 1.1e-33 116.4 45.7 6.2e-29 100.8 16.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AAS53170.1 - 5.5e-05 21.7 11.3 5.5e-05 21.7 7.8 3.6 3 2 1 4 4 4 2 MFS/sugar transport protein LMF1 PF06762.9 AAS53170.1 - 0.014 14.2 0.8 0.023 13.5 0.6 1.3 1 0 0 1 1 1 0 Lipase maturation factor Svf1 PF08622.5 AAS53171.1 - 2.6e-133 444.0 1.0 3.1e-133 443.7 0.7 1.1 1 0 0 1 1 1 1 Svf1-like Homeobox PF00046.24 AAS53172.2 - 8.5e-20 70.1 2.8 1.6e-19 69.2 1.9 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 AAS53172.2 - 0.00068 19.2 1.3 0.0018 17.9 0.9 1.7 1 0 0 1 1 1 1 Homeobox KN domain Aldedh PF00171.17 AAS53173.1 - 2.2e-169 563.6 0.0 2.6e-169 563.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 AAS53173.1 - 0.0045 15.7 0.7 0.029 13.1 0.5 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) YCII PF03795.9 AAS53173.1 - 0.28 11.4 2.1 10 6.4 0.1 3.3 2 1 1 3 3 3 0 YCII-related domain Zn_clus PF00172.13 AAS53174.1 - 5.3e-06 26.2 10.5 8.7e-06 25.5 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_mis_repair PF01119.14 AAS53175.1 - 4.1e-32 110.1 0.2 1.3e-31 108.5 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 AAS53175.1 - 2.3e-12 46.7 0.1 6.4e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AAS53175.1 - 3.9e-10 39.4 0.0 1.5e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_S64 PF08192.6 AAS53175.1 - 0.018 13.4 5.5 0.024 12.9 3.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 Nse4_C PF08743.5 AAS53176.1 - 1.3e-23 82.8 0.0 3.3e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 AAS53176.1 - 4e-10 39.3 0.1 8e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Peptidase_M22 PF00814.20 AAS53177.1 - 1.8e-61 208.0 0.0 2.2e-61 207.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Mito_carr PF00153.22 AAS53178.1 - 3e-63 209.5 1.0 1.7e-21 75.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LNS2 PF08235.8 AAS53179.1 - 7.9e-72 239.9 0.0 1.2e-71 239.3 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 AAS53179.1 - 1.1e-43 147.3 0.0 2.3e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region AF1Q PF15017.1 AAS53179.1 - 1.6e-05 24.7 0.4 1.6e-05 24.7 0.3 2.3 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator Acid_phosphat_B PF03767.9 AAS53179.1 - 0.0057 16.0 0.5 0.029 13.7 0.0 2.2 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_6 PF13344.1 AAS53179.1 - 0.048 13.5 0.0 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase LisH PF08513.6 AAS53180.2 - 1.7e-06 27.5 0.3 2.8e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 LisH PPARgamma_N PF12577.3 AAS53180.2 - 3.2 8.1 10.9 0.036 14.3 0.7 3.1 3 0 0 3 3 3 0 PPAR gamma N-terminal region Vezatin PF12632.2 AAS53181.1 - 1e-37 129.6 6.1 1.9e-37 128.7 4.2 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes UDPGP PF01704.13 AAS53182.1 - 1.3e-52 178.7 0.0 1.6e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 AAS53182.1 - 0.013 15.5 0.1 0.05 13.6 0.1 2.2 2 1 0 2 2 2 0 MobA-like NTP transferase domain Hydrolase PF00702.21 AAS53183.1 - 2.7e-18 67.1 1.3 1e-16 62.0 0.9 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 AAS53183.1 - 2.4e-15 56.1 0.1 7.3e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 AAS53183.1 - 7e-13 49.1 3.8 1.6e-11 44.7 2.7 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AAS53183.1 - 4.8e-12 45.6 0.0 1.6e-11 43.9 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AAS53183.1 - 0.0015 18.1 0.0 0.0065 16.0 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DnaJ PF00226.26 AAS53184.1 - 3.9e-25 87.3 2.1 6.7e-25 86.6 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 AAS53184.1 - 0.03 13.7 0.1 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 A repeated domain in UCH-protein DNA_pol_B PF00136.16 AAS53185.2 - 3.3e-133 444.8 2.8 4.4e-133 444.4 1.9 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 AAS53185.2 - 4.8e-86 288.5 0.0 9.1e-86 287.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 AAS53185.2 - 1.5e-23 82.5 6.2 3.1e-23 81.5 4.3 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 AAS53185.2 - 0.00017 20.4 1.8 0.0031 16.2 0.1 2.3 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.4 AAS53185.2 - 0.0023 17.5 0.0 0.0056 16.2 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 AAS53185.2 - 0.0074 16.1 0.1 0.029 14.1 0.1 1.9 1 1 0 1 1 1 1 RNase_H superfamily Pkinase PF00069.20 AAS53186.2 - 5.8e-70 235.4 0.0 7.1e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53186.2 - 6.5e-36 123.7 0.0 8.9e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 AAS53186.2 - 7.1e-18 64.4 0.4 1.5e-17 63.4 0.3 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 AAS53186.2 - 0.0004 19.5 0.0 0.00061 18.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AAS53186.2 - 0.001 18.0 0.7 7.1 5.4 0.0 3.2 2 1 0 3 3 3 3 Kinase-like YrbL-PhoP_reg PF10707.4 AAS53186.2 - 0.041 13.2 0.5 0.12 11.6 0.3 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 AAS53186.2 - 0.053 12.8 0.4 0.18 11.1 0.3 1.8 1 1 0 1 1 1 0 RIO1 family ATG16 PF08614.6 AAS53188.1 - 1.3e-30 106.6 12.4 9.2e-27 94.1 6.5 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) HAP1_N PF04849.8 AAS53188.1 - 0.00072 18.6 4.6 0.00076 18.5 3.2 1.0 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Fez1 PF06818.10 AAS53188.1 - 0.0013 18.7 2.3 0.0018 18.3 1.6 1.1 1 0 0 1 1 1 1 Fez1 GAS PF13851.1 AAS53188.1 - 0.0068 15.6 4.3 0.0099 15.0 3.0 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding WEMBL PF05701.6 AAS53188.1 - 0.017 13.6 4.7 0.019 13.4 3.3 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light TMF_TATA_bd PF12325.3 AAS53188.1 - 0.024 14.3 2.9 0.033 13.9 2.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Macoilin PF09726.4 AAS53188.1 - 0.048 11.9 1.7 0.053 11.8 1.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Seryl_tRNA_N PF02403.17 AAS53188.1 - 0.074 13.0 2.7 0.12 12.3 1.9 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_1 PF00170.16 AAS53188.1 - 0.087 12.7 3.6 3.1 7.8 0.5 2.4 2 0 0 2 2 2 0 bZIP transcription factor KLRAQ PF10205.4 AAS53188.1 - 0.096 12.7 3.2 0.41 10.7 2.2 1.9 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF4140 PF13600.1 AAS53188.1 - 0.14 12.6 6.0 1 9.8 0.4 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 AAS53188.1 - 0.14 11.7 3.2 0.19 11.3 2.2 1.2 1 0 0 1 1 1 0 IncA protein Phage_GP20 PF06810.6 AAS53188.1 - 0.15 11.5 6.5 0.26 10.7 4.4 1.5 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF972 PF06156.8 AAS53188.1 - 0.17 12.2 2.7 0.26 11.6 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF342 PF03961.8 AAS53188.1 - 0.17 10.2 2.7 0.2 10.0 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3713 PF12506.3 AAS53188.1 - 0.23 11.5 1.4 0.44 10.6 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3713) Spc42p PF11544.3 AAS53188.1 - 0.32 10.9 3.5 1.5 8.8 2.4 2.1 1 1 0 1 1 1 0 Spindle pole body component Spc42p Cluap1 PF10234.4 AAS53188.1 - 0.34 10.0 5.5 0.091 11.9 1.6 1.7 2 0 0 2 2 2 0 Clusterin-associated protein-1 DivIVA PF05103.8 AAS53188.1 - 0.39 10.7 5.5 0.18 11.8 1.2 1.9 1 1 1 2 2 2 0 DivIVA protein DUF1635 PF07795.6 AAS53188.1 - 0.62 9.4 4.5 0.75 9.1 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF848 PF05852.6 AAS53188.1 - 1.1 9.0 4.9 1.8 8.4 3.4 1.3 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) TPD52 PF04201.10 AAS53188.1 - 1.3 8.6 5.0 1.9 8.2 2.5 1.8 1 1 1 2 2 2 0 Tumour protein D52 family bZIP_2 PF07716.10 AAS53188.1 - 2.5 7.9 8.3 0.15 11.8 0.5 2.4 2 1 1 3 3 2 0 Basic region leucine zipper DivIC PF04977.10 AAS53188.1 - 2.9 7.4 6.6 5.5 6.5 0.7 2.3 1 1 1 2 2 2 0 Septum formation initiator TBPIP PF07106.8 AAS53188.1 - 4.6 6.7 7.6 4.5 6.8 3.8 2.0 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PFK PF00365.15 AAS53189.2 - 2.1e-166 551.8 3.6 2.4e-123 410.5 1.7 2.1 2 0 0 2 2 2 2 Phosphofructokinase CBS PF00571.23 AAS53189.2 - 0.079 12.7 0.0 0.73 9.6 0.0 2.6 4 0 0 4 4 4 0 CBS domain Inp1 PF12634.2 AAS53190.2 - 9.6e-37 125.8 0.0 1.5e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Porin_3 PF01459.17 AAS53191.1 - 1e-83 280.8 0.2 1.2e-83 280.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Med9 PF07544.8 AAS53192.1 - 7.1e-24 83.3 0.1 8.8e-24 83.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 CEP76-C2 PF15627.1 AAS53192.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 CEP76 C2 domain ERG2_Sigma1R PF04622.7 AAS53193.1 - 3.2e-90 301.1 0.6 3.8e-90 300.9 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Whi5 PF08528.6 AAS53194.2 - 9.4e-08 31.4 1.0 1.6e-07 30.7 0.7 1.4 1 0 0 1 1 1 1 Whi5 like FLYWCH PF04500.11 AAS53194.2 - 0.087 12.7 0.2 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 FLYWCH zinc finger domain LCAT PF02450.10 AAS53195.1 - 5.8e-124 413.9 0.0 7.3e-124 413.6 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 AAS53195.1 - 0.0041 16.8 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 AAS53195.1 - 0.15 10.9 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Autophagy_N PF03986.8 AAS53196.2 - 3.8e-40 137.0 0.1 6.5e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 AAS53196.2 - 8.5e-24 83.5 0.5 3.4e-23 81.5 0.1 2.2 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 AAS53196.2 - 8e-15 53.6 0.9 1.6e-14 52.6 0.6 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal XPA_C PF05181.7 AAS53197.2 - 4.7e-26 90.1 0.1 9.6e-26 89.1 0.1 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 AAS53197.2 - 0.074 12.7 0.7 0.074 12.7 0.5 1.9 2 0 0 2 2 2 0 XPA protein N-terminal vMSA PF00695.14 AAS53197.2 - 0.095 11.8 1.2 2 7.5 0.1 2.1 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus NMD3 PF04981.8 AAS53197.2 - 5.1 6.1 9.3 1.1 8.3 1.0 2.4 2 0 0 2 2 2 0 NMD3 family VHS PF00790.14 AAS53198.1 - 2.4e-37 127.6 0.1 5.1e-37 126.6 0.1 1.5 1 0 0 1 1 1 1 VHS domain FYVE PF01363.16 AAS53198.1 - 9.4e-20 70.2 3.1 9.4e-20 70.2 2.1 2.1 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.11 AAS53198.1 - 0.00014 21.7 1.5 0.00014 21.7 1.0 2.5 3 0 0 3 3 3 1 FYVE-type zinc finger UIM PF02809.15 AAS53198.1 - 0.0039 16.6 1.9 0.0039 16.6 1.3 4.3 4 0 0 4 4 4 1 Ubiquitin interaction motif Rot1 PF10681.4 AAS53199.2 - 4.1e-91 304.0 0.0 4.7e-91 303.8 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Cyclin_N PF00134.18 AAS53200.1 - 5.9e-39 132.5 0.0 1.3e-38 131.3 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF1053 PF06327.9 AAS53200.1 - 0.12 12.6 1.4 0.22 11.9 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) BBP1_C PF15272.1 AAS53202.2 - 2.3e-54 183.9 20.9 4e-54 183.1 14.5 1.4 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal BBP1_N PF15271.1 AAS53202.2 - 9.3e-38 129.8 0.7 1.3e-36 126.1 0.0 2.4 2 1 0 2 2 2 1 Spindle pole body component BBP1, Mps2-binding protein Fib_alpha PF08702.5 AAS53202.2 - 0.44 10.6 9.6 0.39 10.8 5.5 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family COG2 PF06148.6 AAS53202.2 - 3.5 7.5 8.0 9.6 6.0 5.6 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 SAGA-Tad1 PF12767.2 AAS53203.2 - 1.5e-76 257.4 0.0 1.9e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 AAS53203.2 - 0.0061 15.8 0.0 0.011 15.0 0.0 1.4 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family ERM PF00769.14 AAS53204.1 - 0.0022 17.5 15.5 0.0022 17.5 10.7 3.3 1 1 1 2 2 2 1 Ezrin/radixin/moesin family DUF2392 PF10288.4 AAS53204.1 - 0.12 12.7 1.6 0.26 11.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2392) Filament PF00038.16 AAS53204.1 - 1.6 8.1 45.1 0.7 9.2 8.1 2.3 1 1 1 2 2 2 0 Intermediate filament protein Baculo_PEP_C PF04513.7 AAS53204.1 - 7.8 6.3 13.6 16 5.3 3.1 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fer2 PF00111.22 AAS53205.1 - 1e-14 53.9 0.2 1.4e-14 53.5 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain V-SNARE_C PF12352.3 AAS53206.1 - 8.4e-17 60.9 2.7 8.4e-17 60.9 1.9 2.5 2 1 1 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 AAS53206.1 - 7.3e-15 54.8 1.9 7.3e-15 54.8 1.3 2.2 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 AAS53206.1 - 0.0038 16.8 5.2 0.0092 15.6 1.0 2.5 2 1 0 2 2 2 1 Sec20 DUF3490 PF11995.3 AAS53206.1 - 0.02 14.4 0.2 0.044 13.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3490) TMEM247 PF15444.1 AAS53206.1 - 0.086 12.6 0.3 0.13 12.0 0.2 1.6 1 1 0 1 1 1 0 Transmembrane protein 247 Flg_hook PF02120.11 AAS53206.1 - 0.092 12.4 0.3 0.092 12.4 0.2 2.9 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK Kinetocho_Slk19 PF12709.2 AAS53206.1 - 0.095 12.7 0.1 0.095 12.7 0.1 2.3 3 0 0 3 3 3 0 Central kinetochore-associated Mnd1 PF03962.10 AAS53206.1 - 0.51 9.9 6.2 0.34 10.5 0.5 2.0 1 1 1 2 2 2 0 Mnd1 family Glyco_hydro_63 PF03200.11 AAS53207.2 - 4.1e-08 31.5 2.2 4.1e-05 21.6 0.1 3.5 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase DUF1903 PF08991.5 AAS53209.1 - 1.1e-29 102.3 9.3 1.5e-29 101.8 6.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 AAS53209.1 - 0.59 10.1 4.8 0.88 9.5 3.3 1.3 1 0 0 1 1 1 0 CHCH domain Cmc1 PF08583.5 AAS53209.1 - 2.3 8.0 8.7 1.6 8.5 0.9 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 AAS53209.1 - 6 6.9 9.6 3.6 7.6 0.2 2.8 1 1 3 4 4 4 0 Cytochrome C oxidase copper chaperone (COX17) Ribosomal_L36e PF01158.13 AAS53211.1 - 1.8e-38 130.4 3.6 2e-38 130.3 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Ribosomal_L28 PF00830.14 AAS53212.1 - 8e-22 76.8 0.5 1.6e-21 75.8 0.3 1.6 1 0 0 1 1 1 1 Ribosomal L28 family RabGAP-TBC PF00566.13 AAS53213.2 - 2.3e-51 174.3 1.2 2.3e-51 174.3 0.8 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Gal4_dimer PF03902.8 AAS53214.1 - 1.4e-25 88.9 1.1 2.8e-25 87.9 0.8 1.6 1 0 0 1 1 1 1 Gal4-like dimerisation domain Fungal_trans PF04082.13 AAS53214.1 - 3.4e-20 72.0 0.1 5.3e-20 71.3 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS53214.1 - 2.4e-07 30.5 15.1 4.2e-07 29.7 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CK2S PF15011.1 AAS53214.1 - 0.045 13.5 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 Casein Kinase 2 substrate RQC PF09382.5 AAS53215.2 - 3.1e-28 97.5 0.4 6.1e-28 96.6 0.3 1.5 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 AAS53215.2 - 1.1e-21 77.0 0.0 3.3e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS53215.2 - 7.9e-21 73.7 0.0 7e-19 67.4 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_Sgs1 PF11408.3 AAS53215.2 - 5.6e-07 29.2 0.1 1.3e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Sgs1 RecQ helicase ACP_syn_III_C PF08541.5 AAS53215.2 - 0.05 13.6 0.0 1.8 8.6 0.0 3.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal MFS_1 PF07690.11 AAS53216.1 - 1.6e-22 79.7 14.3 2.2e-22 79.2 9.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.27 AAS53217.2 - 4.3e-20 70.7 6.4 2.8e-08 33.3 0.0 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Ribosomal_S17 PF00366.15 AAS53218.2 - 1.4e-15 57.0 1.0 2.5e-15 56.2 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 DUF4570 PF15134.1 AAS53218.2 - 0.1 12.4 5.7 0.54 10.1 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) RteC PF09357.5 AAS53218.2 - 0.17 11.6 1.8 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 RteC protein OprB PF04966.7 AAS53218.2 - 0.19 10.8 0.7 0.23 10.5 0.5 1.1 1 0 0 1 1 1 0 Carbohydrate-selective porin, OprB family Rhomboid PF01694.17 AAS53219.1 - 2.5e-17 63.2 13.8 3.9e-17 62.6 9.5 1.3 1 0 0 1 1 1 1 Rhomboid family DUF2417 PF10329.4 AAS53219.1 - 0.32 10.3 4.1 0.075 12.4 0.7 1.5 2 0 0 2 2 2 0 Region of unknown function (DUF2417) UAA PF08449.6 AAS53220.2 - 2.7e-70 236.6 6.0 3.1e-70 236.4 4.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 AAS53220.2 - 3.4e-08 33.5 13.5 2.1e-07 30.9 2.9 3.0 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 AAS53220.2 - 1e-07 31.7 5.7 1e-07 31.7 4.0 2.3 3 0 0 3 3 3 1 Triose-phosphate Transporter family EmrE PF13536.1 AAS53220.2 - 0.001 19.2 6.0 0.001 19.2 4.2 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter DUF3353 PF11833.3 AAS53220.2 - 0.35 10.3 5.0 0.13 11.6 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) RINGv PF12906.2 AAS53222.1 - 0.0081 16.1 7.6 0.022 14.7 5.3 1.8 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 AAS53222.1 - 0.68 9.9 7.2 1.2 9.1 2.4 2.6 2 0 0 2 2 2 0 FANCL C-terminal domain RasGAP_C PF03836.10 AAS53224.2 - 5.2e-37 126.7 2.6 5.2e-37 126.7 1.8 2.9 3 0 0 3 3 3 1 RasGAP C-terminus RasGAP PF00616.14 AAS53224.2 - 2.8e-11 43.4 0.1 9.1e-11 41.7 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 AAS53224.2 - 1.1e-07 31.8 0.1 1.3e-06 28.4 0.0 2.9 3 0 0 3 3 3 1 Calponin homology (CH) domain IQ PF00612.22 AAS53224.2 - 8.6e-05 21.8 21.1 2.3 8.0 0.4 7.8 8 0 0 8 8 8 4 IQ calmodulin-binding motif Trypan_PARP PF05887.6 AAS53224.2 - 0.00017 21.4 26.0 0.00017 21.4 18.0 1.8 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 AAS53224.2 - 7.3 4.8 20.9 15 3.7 14.5 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein TBCC PF07986.7 AAS53225.1 - 0.00019 20.8 2.2 0.00078 18.8 1.5 2.0 1 1 0 1 1 1 1 Tubulin binding cofactor C HSP90 PF00183.13 AAS53226.1 - 8.3e-253 839.5 38.3 9.8e-253 839.3 26.5 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 AAS53226.1 - 2.2e-11 43.4 0.0 4.6e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AAS53226.1 - 2.2e-10 40.3 0.0 2.2e-10 40.3 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2435 PF10363.4 AAS53227.1 - 7.9e-25 86.5 0.0 4.3e-24 84.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 AAS53227.1 - 1.5e-07 30.7 0.2 4.7e-07 29.1 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) HEAT PF02985.17 AAS53227.1 - 0.0032 17.4 1.3 7.8 6.8 0.1 4.5 3 0 0 3 3 3 2 HEAT repeat DUF4484 PF14831.1 AAS53227.1 - 0.0068 16.5 0.6 0.077 13.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4484) Ank PF00023.25 AAS53228.1 - 3.8e-17 61.1 2.1 2.1e-08 33.5 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 AAS53228.1 - 1.7e-16 60.2 4.9 7.4e-09 35.8 0.3 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 AAS53228.1 - 2.5e-16 59.3 3.8 5.7e-09 35.9 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 AAS53228.1 - 2.8e-15 56.4 0.2 5.1e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AAS53228.1 - 8e-14 50.3 1.3 1.3e-05 24.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat eIF-5_eIF-2B PF01873.12 AAS53229.2 - 1e-44 151.1 0.2 1.6e-44 150.5 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.10 AAS53229.2 - 0.0031 17.1 0.1 0.045 13.4 0.0 2.7 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region TF_Zn_Ribbon PF08271.7 AAS53229.2 - 0.096 12.0 0.2 0.24 10.7 0.1 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding Pkinase PF00069.20 AAS53231.1 - 1.3e-25 90.0 0.0 2.7e-25 89.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53231.1 - 4.7e-09 35.6 0.0 1.7e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase TIP49 PF06068.8 AAS53232.2 - 8.3e-179 594.4 3.0 9.9e-179 594.1 2.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 AAS53232.2 - 7e-08 32.7 3.9 4.1e-05 23.7 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AAS53232.2 - 4.7e-07 29.0 3.1 0.00064 18.8 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AAS53232.2 - 1.2e-05 25.4 0.1 0.029 14.5 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_14 PF13173.1 AAS53232.2 - 1.4e-05 24.9 0.1 2.3 8.1 0.0 3.4 3 1 0 3 3 3 3 AAA domain DnaB_C PF03796.10 AAS53232.2 - 5.6e-05 22.1 1.0 9.5e-05 21.3 0.1 1.8 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 AAS53232.2 - 0.00019 21.4 0.0 0.0032 17.4 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 AAS53232.2 - 0.0053 16.4 0.7 0.97 9.1 0.0 3.1 2 2 1 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AAS53232.2 - 0.0086 15.2 0.8 0.21 10.7 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 AAS53232.2 - 0.0098 15.3 0.3 0.02 14.3 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AAS53232.2 - 0.013 15.4 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AAS53232.2 - 0.026 14.2 0.1 0.07 12.8 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain TFIID_20kDa PF03847.8 AAS53232.2 - 0.049 13.9 0.1 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A ATP-synt_C PF00137.16 AAS53233.1 - 1.4e-26 92.1 31.0 1.5e-15 56.8 4.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Mis14 PF08641.7 AAS53234.1 - 1.5e-35 122.2 0.8 1.5e-35 122.2 0.6 1.7 2 0 0 2 2 2 1 Kinetochore protein Mis14 like TFIID_30kDa PF03540.8 AAS53234.1 - 0.065 13.0 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit SNARE PF05739.14 AAS53235.1 - 8.4e-15 54.2 7.0 8.4e-15 54.2 4.8 2.4 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 AAS53235.1 - 0.0001 22.4 6.1 0.0001 22.4 4.2 2.5 2 1 0 2 2 2 1 Syntaxin Thr_dehydrat_C PF00585.13 AAS53235.1 - 0.0021 17.6 1.5 0.0093 15.5 0.0 2.6 2 1 1 3 3 3 1 C-terminal regulatory domain of Threonine dehydratase Synaptobrevin PF00957.16 AAS53235.1 - 0.0025 17.4 2.9 0.0025 17.4 2.0 2.0 2 0 0 2 2 2 1 Synaptobrevin Rifin_STEVOR PF02009.11 AAS53235.1 - 0.052 13.1 10.1 0.13 11.8 6.2 1.9 1 1 1 2 2 2 0 Rifin/stevor family T2SF PF00482.18 AAS53235.1 - 0.065 13.1 3.5 0.045 13.6 0.5 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F PTA_PTB PF01515.14 AAS53235.1 - 0.091 11.8 4.8 0.16 11.0 3.3 1.3 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase DDE_Tnp_1 PF01609.16 AAS53235.1 - 0.098 12.1 0.5 0.19 11.2 0.4 1.5 1 0 0 1 1 1 0 Transposase DDE domain DUF1542 PF07564.6 AAS53235.1 - 0.29 11.1 10.9 3.6 7.6 2.3 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) DUF3708 PF12501.3 AAS53235.1 - 0.79 9.5 10.7 0.48 10.2 1.8 2.3 1 1 0 2 2 2 0 Phosphate ATP-binding cassette transporter OppC_N PF12911.2 AAS53235.1 - 0.84 9.0 2.7 1.8 8.0 1.8 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Allexi_40kDa PF05549.6 AAS53235.1 - 3.2 6.9 6.1 4.6 6.4 0.2 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF745 PF05335.8 AAS53235.1 - 5 6.6 20.7 0.038 13.5 5.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF4094 PF13334.1 AAS53235.1 - 7.2 7.0 7.8 0.51 10.7 0.1 2.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4094) DUF1664 PF07889.7 AAS53235.1 - 9.9 5.9 9.0 0.85 9.4 1.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ketoacyl-synt PF00109.21 AAS53236.2 - 1.4e-17 64.0 0.0 2.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 AAS53236.2 - 2.9e-15 56.0 0.0 8e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 AAS53236.2 - 2.2e-12 46.8 0.0 7e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain DUF3597 PF12200.3 AAS53236.2 - 0.83 10.0 7.3 4 7.8 5.0 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) zf-C2H2 PF00096.21 AAS53238.2 - 3.6e-10 39.5 10.5 3.4e-05 23.9 0.9 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS53238.2 - 2.3e-09 36.9 7.3 0.00055 20.0 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AAS53238.2 - 2.3e-09 37.0 2.2 2.3e-09 37.0 1.5 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 AAS53238.2 - 0.00011 22.2 3.2 0.012 15.7 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 AAS53238.2 - 0.0028 17.7 4.9 0.0065 16.6 0.8 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 AAS53238.2 - 0.032 14.3 3.4 0.092 12.9 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AAS53238.2 - 0.035 13.9 2.0 0.066 13.1 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger PA_decarbox PF05870.6 AAS53239.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) mRNA_triPase PF02940.10 AAS53240.2 - 5.5e-59 199.4 1.7 8.3e-59 198.9 1.1 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain SIP1 PF04938.7 AAS53240.2 - 0.041 13.2 0.1 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Glycos_transf_2 PF00535.21 AAS53241.2 - 3.4e-28 98.4 0.0 4.4e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AAS53241.2 - 5.4e-12 45.9 0.0 8.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 AAS53241.2 - 0.00012 22.3 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 ABC_tran PF00005.22 AAS53243.2 - 1.2e-46 158.4 0.1 6.8e-26 91.1 0.0 4.1 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 AAS53243.2 - 2e-17 64.0 1.5 4.7e-07 30.0 0.1 3.9 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 AAS53243.2 - 3.3e-11 42.8 0.0 0.00042 19.6 0.0 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 AAS53243.2 - 2.7e-08 33.3 4.2 5.3e-08 32.4 2.9 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 AAS53243.2 - 9.9e-08 31.4 1.0 0.0043 16.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 AAS53243.2 - 2.3e-07 31.6 0.4 0.012 16.4 0.0 3.9 4 0 0 4 4 3 2 AAA domain AAA_23 PF13476.1 AAS53243.2 - 3.3e-07 30.8 3.4 0.0011 19.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 AAS53243.2 - 2e-06 27.7 0.0 0.014 15.3 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 AAS53243.2 - 2e-06 27.1 0.1 0.0076 15.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 AAS53243.2 - 3.7e-06 26.2 0.2 0.33 9.9 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 AAS53243.2 - 4.5e-06 26.8 0.1 0.11 12.6 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_10 PF12846.2 AAS53243.2 - 1.9e-05 24.2 2.4 0.27 10.6 0.1 4.2 4 1 0 4 4 4 2 AAA-like domain Miro PF08477.8 AAS53243.2 - 0.00016 22.1 0.0 0.063 13.7 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 AAS53243.2 - 0.00026 19.8 0.2 0.49 9.1 0.0 2.6 2 0 0 2 2 2 2 ArgK protein DUF87 PF01935.12 AAS53243.2 - 0.00028 20.7 5.4 0.078 12.7 0.0 4.3 4 1 0 4 4 4 1 Domain of unknown function DUF87 MobB PF03205.9 AAS53243.2 - 0.00051 19.7 0.1 0.15 11.7 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 AAS53243.2 - 0.00053 20.2 0.2 0.068 13.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 AAS53243.2 - 0.00072 19.5 0.0 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 AAS53243.2 - 0.00087 18.9 0.1 0.94 9.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 AAS53243.2 - 0.001 19.2 0.1 1.1 9.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.18 AAS53243.2 - 0.0011 18.7 0.1 0.3 10.9 0.0 3.5 3 0 0 3 3 3 1 Dynamin family AAA_33 PF13671.1 AAS53243.2 - 0.0013 18.6 0.0 0.61 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 AAS53243.2 - 0.0028 17.2 0.7 4.8 6.7 0.1 3.5 3 1 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 AAS53243.2 - 0.0047 16.8 0.1 1.8 8.5 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 AAS53243.2 - 0.0065 15.0 0.1 1.8 6.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 AAS53243.2 - 0.015 14.7 0.0 4.5 6.7 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 AAS53243.2 - 0.023 14.8 0.0 3.4 7.8 0.0 3.0 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 AAS53243.2 - 0.036 13.1 0.4 5.1 6.1 0.0 3.0 4 0 0 4 4 3 0 Zeta toxin DUF3584 PF12128.3 AAS53243.2 - 0.038 11.3 0.9 2.9 5.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) FtsK_SpoIIIE PF01580.13 AAS53243.2 - 0.048 13.1 0.5 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.1 AAS53243.2 - 0.049 13.5 0.0 1.7 8.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 AAS53243.2 - 0.066 12.1 0.6 3.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 AAS53243.2 - 0.071 12.5 0.0 10 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 AAS53243.2 - 0.094 12.4 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 NTPase ATP-synt_ab PF00006.20 AAS53243.2 - 0.1 12.0 0.2 4.1 6.8 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain MutS_V PF00488.16 AAS53243.2 - 0.11 11.9 0.2 8.7 5.6 0.0 2.3 2 0 0 2 2 2 0 MutS domain V cobW PF02492.14 AAS53243.2 - 0.13 11.6 0.9 23 4.3 0.0 3.3 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran_2 PF12848.2 AAS53243.2 - 1.1 9.1 7.3 0.14 11.9 0.4 2.6 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 AAS53243.2 - 1.6 8.6 7.1 1.2 9.0 0.0 3.6 4 1 0 4 4 4 0 AAA ATPase domain MoCF_biosynth PF00994.19 AAS53244.1 - 2e-32 111.5 0.0 3.1e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Polysacc_synt_4 PF04669.8 AAS53245.1 - 7.8e-21 74.3 0.8 5.7e-20 71.4 0.6 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Cation_efflux PF01545.16 AAS53246.2 - 4.7e-52 176.8 4.0 6.1e-52 176.4 2.8 1.1 1 0 0 1 1 1 1 Cation efflux family ARID PF01388.16 AAS53247.1 - 7.2e-26 89.8 0.5 1.8e-25 88.5 0.0 2.0 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain JmjC PF02373.17 AAS53247.1 - 7.9e-13 48.6 0.0 4.4e-07 30.1 0.0 2.6 2 0 0 2 2 2 2 JmjC domain, hydroxylase PLU-1 PF08429.6 AAS53247.1 - 7.9e-12 44.7 0.0 2.1e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 PLU-1-like protein PHD PF00628.24 AAS53247.1 - 1.5e-05 24.5 9.6 3.3e-05 23.4 6.6 1.6 1 0 0 1 1 1 1 PHD-finger JmjN PF02375.12 AAS53247.1 - 0.025 14.1 0.0 0.058 12.9 0.0 1.7 1 0 0 1 1 1 0 jmjN domain CRPV_capsid PF08762.5 AAS53247.1 - 0.09 12.1 0.3 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 CRPV capsid protein like Keratin_B2 PF01500.12 AAS53248.2 - 0.35 10.6 28.3 0.46 10.2 19.6 1.1 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein Keratin_B2_2 PF13885.1 AAS53248.2 - 1.4 8.6 40.7 52 3.6 28.2 2.2 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein GCR1_C PF12550.3 AAS53250.1 - 1.9e-25 88.5 1.2 1.9e-25 88.5 0.8 1.8 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes PLAC9 PF15205.1 AAS53250.1 - 0.051 13.8 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Placenta-specific protein 9 MitMem_reg PF13012.1 AAS53250.1 - 0.058 13.4 2.2 0.17 11.9 1.5 1.9 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function HR1 PF02185.11 AAS53250.1 - 1.1 9.0 5.8 0.73 9.6 0.4 2.5 2 0 0 2 2 2 0 Hr1 repeat SlyX PF04102.7 AAS53250.1 - 1.8 9.0 8.4 0.14 12.5 1.8 2.2 2 0 0 2 2 2 0 SlyX UPF0061 PF02696.9 AAS53251.2 - 1.8e-140 468.5 0.0 2.2e-140 468.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Lon_C PF05362.8 AAS53253.2 - 4.3e-43 147.0 0.0 7.1e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 AAS53253.2 - 1.5e-18 67.2 0.0 3.7e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AAS53253.2 - 3.8e-08 33.1 0.0 1.7e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 AAS53253.2 - 3.1e-06 26.7 0.0 5.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase LON PF02190.11 AAS53253.2 - 5.9e-06 26.1 0.0 4.4e-05 23.2 0.0 2.3 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain RuvB_N PF05496.7 AAS53253.2 - 3.8e-05 22.8 0.0 9.4e-05 21.5 0.0 1.5 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AAS53253.2 - 8.9e-05 22.5 0.1 0.00049 20.1 0.0 2.3 2 0 0 2 2 1 1 AAA ATPase domain AAA_17 PF13207.1 AAS53253.2 - 0.00013 22.8 0.0 0.00033 21.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 AAS53253.2 - 0.00016 21.6 0.0 0.00039 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AAS53253.2 - 0.00031 20.8 0.0 0.036 14.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 AAS53253.2 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 AAS53253.2 - 0.01 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AAS53253.2 - 0.012 15.5 0.0 0.046 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 AAS53253.2 - 0.015 15.0 0.0 0.05 13.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 AAS53253.2 - 0.016 14.3 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 AAS53253.2 - 0.027 13.6 0.0 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 AAS53253.2 - 0.038 12.6 0.0 0.14 10.8 0.0 1.8 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 AAS53253.2 - 0.063 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 AAS53253.2 - 0.066 12.7 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AAS53253.2 - 0.069 12.5 0.1 1.9 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 AAS53253.2 - 0.093 12.4 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.1 AAS53253.2 - 0.13 11.8 0.9 1 8.9 0.0 2.8 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.17 AAS53253.2 - 0.19 11.9 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 AAS53253.2 - 0.21 10.3 0.0 0.94 8.2 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain TRP PF06011.7 AAS53254.1 - 3.2e-143 477.4 34.9 3.8e-143 477.2 24.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 AAS53254.1 - 1.6e-42 144.9 0.2 2.6e-42 144.2 0.2 1.4 1 0 0 1 1 1 1 ML-like domain Med7 PF05983.6 AAS53255.1 - 0.026 14.2 0.5 0.057 13.1 0.3 1.6 1 1 0 1 1 1 0 MED7 protein Coatomer_WDAD PF04053.9 AAS53256.1 - 1.3e-165 551.4 1.1 3.7e-164 546.7 0.1 2.1 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 AAS53256.1 - 7.6e-46 152.4 5.9 2e-10 40.1 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 AAS53256.1 - 1.4e-06 26.7 3.1 0.031 12.4 0.0 4.6 3 1 1 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 AAS53256.1 - 5.6e-06 26.1 0.1 0.21 11.3 0.0 4.9 3 2 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region TPR_8 PF13181.1 AAS53256.1 - 0.0034 17.0 1.0 0.32 10.8 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 AAS53256.1 - 0.03 14.1 0.1 0.23 11.3 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Poly_export PF02563.11 AAS53256.1 - 0.12 12.0 0.0 3.7 7.3 0.0 2.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein TPR_11 PF13414.1 AAS53256.1 - 1.1 8.9 5.3 2.5 7.8 1.1 3.2 2 1 1 3 3 3 0 TPR repeat FtsJ PF01728.14 AAS53257.2 - 2.2e-60 203.7 0.0 3.3e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 AAS53257.2 - 4.7e-05 23.9 0.0 0.00019 21.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AAS53257.2 - 0.00013 21.7 0.0 0.00074 19.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS53257.2 - 0.0022 17.6 0.0 0.37 10.3 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Ribosomal_L1 PF00687.16 AAS53258.1 - 2.5e-46 157.8 2.4 2.8e-46 157.6 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Vesiculo_matrix PF06326.7 AAS53258.1 - 0.061 12.7 0.1 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 Vesiculovirus matrix protein Cyclin PF08613.6 AAS53259.1 - 9.2e-14 52.0 0.0 1.6e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin Arf PF00025.16 AAS53260.1 - 3e-65 218.7 0.0 3.4e-65 218.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 AAS53260.1 - 6.6e-09 34.9 0.6 9.3e-06 24.5 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 AAS53260.1 - 2.1e-08 34.6 0.0 3.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 AAS53260.1 - 2e-07 30.5 0.0 2.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 AAS53260.1 - 9.9e-07 28.1 0.0 1.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AAS53260.1 - 2.3e-05 24.3 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 AAS53260.1 - 0.00036 19.7 0.0 0.00038 19.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 AAS53260.1 - 0.042 13.3 0.0 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF663 PF04950.7 AAS53261.2 - 1.8e-102 342.3 0.1 1.8e-102 342.3 0.1 2.0 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 AAS53261.2 - 2e-27 94.5 0.0 4.9e-27 93.2 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 AAS53261.2 - 2.5e-08 33.5 0.0 4.6e-06 26.2 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 AAS53261.2 - 1.4e-06 29.1 0.0 1.4e-06 29.1 0.0 4.1 4 2 1 5 5 2 1 AAA domain AAA PF00004.24 AAS53261.2 - 4.7e-06 26.8 0.0 1.4e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 AAS53261.2 - 1.1e-05 25.3 0.0 3.8e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AAS53261.2 - 2.3e-05 24.4 0.0 8.1e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 AAS53261.2 - 2.3e-05 24.0 0.3 6.9e-05 22.5 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain MobB PF03205.9 AAS53261.2 - 4e-05 23.3 0.6 0.00018 21.2 0.4 2.2 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 AAS53261.2 - 6.9e-05 22.7 0.3 0.00093 19.1 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_22 PF13401.1 AAS53261.2 - 9.9e-05 22.4 0.0 0.0003 20.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 AAS53261.2 - 0.0021 18.5 0.0 0.0091 16.4 0.0 2.3 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 AAS53261.2 - 0.0026 17.7 0.4 0.011 15.7 0.2 2.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 AAS53261.2 - 0.0028 17.9 0.0 0.0028 17.9 0.0 2.6 3 0 0 3 3 2 1 ABC transporter NACHT PF05729.7 AAS53261.2 - 0.0028 17.3 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 AAS53261.2 - 0.0037 17.5 0.1 0.0037 17.5 0.0 4.2 4 1 0 4 4 3 1 AAA domain AAA_25 PF13481.1 AAS53261.2 - 0.005 16.2 0.0 0.015 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 AAS53261.2 - 0.0099 16.0 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 AAS53261.2 - 0.011 15.3 0.3 0.011 15.3 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 AAS53261.2 - 0.014 15.1 0.1 0.043 13.5 0.1 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 AAS53261.2 - 0.014 15.0 0.9 0.029 14.0 0.6 1.5 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 AAS53261.2 - 0.018 14.2 0.1 0.69 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 cobW PF02492.14 AAS53261.2 - 0.021 14.2 0.1 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 AAS53261.2 - 0.025 14.0 0.0 0.21 11.0 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.1 AAS53261.2 - 0.048 13.2 0.0 0.048 13.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 AAS53261.2 - 1.2 8.9 4.1 5.1 6.8 0.0 3.6 2 1 0 3 3 3 0 Dynamin family WAC_Acf1_DNA_bd PF10537.4 AAS53262.2 - 3.5e-37 126.6 1.6 3.5e-37 126.6 1.1 2.3 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 AAS53262.2 - 7.4e-17 60.8 3.0 1.2e-14 53.8 0.3 2.6 2 0 0 2 2 2 2 DDT domain WHIM2 PF15613.1 AAS53262.2 - 4.4e-07 29.5 1.3 7.9e-07 28.7 0.2 2.1 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 AAS53262.2 - 0.024 14.5 0.1 0.16 11.9 0.1 2.5 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 AAS53262.2 - 0.12 12.1 1.3 0.33 10.7 0.9 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 DUF3782 PF12644.2 AAS53262.2 - 2.3 8.0 0.0 2.3 8.0 0.0 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3782) Ubiq_cyt_C_chap PF03981.7 AAS53263.2 - 3.5e-43 146.8 0.6 5.3e-43 146.2 0.4 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone 2C_adapt PF08793.5 AAS53263.2 - 0.058 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 2-cysteine adaptor domain HK PF02110.10 AAS53264.1 - 9.3e-71 237.8 0.1 1.4e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 AAS53264.1 - 2e-54 183.4 0.0 3.1e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 AAS53264.1 - 0.00093 18.4 0.6 0.012 14.7 0.1 2.8 3 1 0 3 3 3 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.12 AAS53264.1 - 0.049 12.8 0.0 0.13 11.5 0.0 1.8 1 1 0 1 1 1 0 Carbohydrate kinase LRR_9 PF14580.1 AAS53265.1 - 7.9e-11 41.8 0.3 1.6e-10 40.8 0.1 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 AAS53265.1 - 1.3e-07 31.0 6.2 0.003 17.1 0.2 2.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AAS53265.1 - 0.0028 17.4 7.1 7.7 6.9 0.0 4.6 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.1 AAS53265.1 - 0.045 13.8 1.9 34 4.9 0.1 3.9 2 1 0 2 2 2 0 Leucine Rich repeat LRR_8 PF13855.1 AAS53265.1 - 0.33 10.7 5.6 10 5.9 3.8 2.6 1 1 1 2 2 2 0 Leucine rich repeat LRR_7 PF13504.1 AAS53265.1 - 2.3 8.7 6.7 1e+02 3.8 0.1 4.6 4 0 0 4 4 4 0 Leucine rich repeat PHD PF00628.24 AAS53266.2 - 7.3e-14 51.2 50.8 2.9e-07 30.0 6.4 5.7 6 0 0 6 6 6 3 PHD-finger zf-HC5HC2H_2 PF13832.1 AAS53266.2 - 7.2e-13 48.5 0.9 7.2e-13 48.5 0.6 5.1 5 1 0 5 5 5 2 PHD-zinc-finger like domain BAH PF01426.13 AAS53266.2 - 2e-11 43.6 0.2 5.6e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 BAH domain PHD_2 PF13831.1 AAS53266.2 - 1.2e-08 34.0 9.7 5.2e-08 32.0 1.6 5.1 6 0 0 6 6 6 3 PHD-finger Myb_DNA-binding PF00249.26 AAS53266.2 - 0.022 14.8 0.0 0.068 13.2 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-RING-like PF08746.6 AAS53266.2 - 0.5 10.4 24.9 3.5 7.6 1.3 5.1 4 0 0 4 4 4 0 RING-like domain mRNA_cap_enzyme PF01331.14 AAS53267.1 - 2.7e-56 190.3 0.0 5.6e-56 189.2 0.0 1.5 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 AAS53267.1 - 1.7e-22 79.6 0.3 1.3e-21 76.8 0.2 2.3 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 AAS53267.1 - 1e-06 28.3 0.0 2.6e-05 23.7 0.0 2.7 2 1 0 2 2 2 1 ATP dependent DNA ligase domain LTXXQ PF07813.7 AAS53267.1 - 0.094 13.1 0.3 0.23 11.9 0.2 1.7 1 1 0 1 1 1 0 LTXXQ motif family protein DUF845 PF05820.6 AAS53267.1 - 0.15 11.8 0.0 0.46 10.2 0.0 1.7 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF845) DAP3 PF10236.4 AAS53268.2 - 5.2e-86 288.3 0.1 6.6e-86 288.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 AAS53268.2 - 1.8e-05 24.8 0.0 3.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ArgK PF03308.11 AAS53268.2 - 0.0013 17.6 0.1 0.0023 16.7 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 AAS53268.2 - 0.0013 18.1 0.0 0.0069 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 AAS53268.2 - 0.0016 18.1 0.0 0.0065 16.2 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_17 PF13207.1 AAS53268.2 - 0.002 18.9 0.0 0.0046 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AAS53268.2 - 0.0023 17.6 0.1 0.0076 15.9 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 AAS53268.2 - 0.0024 17.3 0.0 0.006 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 AAS53268.2 - 0.0027 17.9 0.0 0.0091 16.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 AAS53268.2 - 0.0029 16.7 0.0 0.0073 15.4 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_10 PF12846.2 AAS53268.2 - 0.0043 16.5 0.0 0.0091 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain DUF258 PF03193.11 AAS53268.2 - 0.0044 16.2 0.0 0.0079 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 AAS53268.2 - 0.0073 15.7 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.1 AAS53268.2 - 0.0083 15.7 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AAS53268.2 - 0.014 15.5 0.1 0.079 13.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 AAS53268.2 - 0.016 15.3 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 AAS53268.2 - 0.018 13.8 0.0 0.039 12.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 AAS53268.2 - 0.02 14.6 0.2 0.42 10.2 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 AAS53268.2 - 0.029 14.0 0.5 0.091 12.4 0.0 2.1 3 0 0 3 3 1 0 NACHT domain AAA_14 PF13173.1 AAS53268.2 - 0.037 13.9 0.1 0.1 12.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 AAS53268.2 - 0.037 14.3 0.1 0.095 12.9 0.1 1.8 1 1 0 1 1 1 0 ABC transporter Miro PF08477.8 AAS53268.2 - 0.051 14.0 0.0 0.096 13.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein DUF815 PF05673.8 AAS53268.2 - 0.055 12.3 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KTI12 PF08433.5 AAS53268.2 - 0.055 12.6 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 AAS53268.2 - 0.06 13.3 0.1 0.13 12.2 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 AAS53268.2 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 AAS53268.2 - 0.064 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 AAS53268.2 - 0.069 12.7 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 AAS53268.2 - 0.099 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PseudoU_synth_1 PF01416.15 AAS53269.2 - 7.2e-24 84.2 0.0 1.3e-11 44.8 0.0 2.8 3 0 0 3 3 3 2 tRNA pseudouridine synthase PRK PF00485.13 AAS53269.2 - 0.085 12.4 0.4 0.16 11.5 0.3 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family UPF0113 PF03657.8 AAS53270.1 - 7.2e-12 45.2 0.0 9.7e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 AAS53270.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.8 1 1 1 2 2 2 0 pre-rRNA processing and ribosome biogenesis SRP72 PF08492.7 AAS53271.1 - 2.1e-17 63.2 1.5 2.1e-17 63.2 1.1 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.1 AAS53271.1 - 4.8e-06 26.4 4.5 2.1e-05 24.3 0.4 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 AAS53271.1 - 0.0071 16.0 2.0 0.036 13.8 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 AAS53271.1 - 0.013 15.2 0.8 0.16 11.8 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 AAS53271.1 - 0.021 14.4 0.0 0.021 14.4 0.0 3.0 4 1 1 5 5 5 0 TPR repeat TPR_1 PF00515.23 AAS53271.1 - 0.021 14.4 0.3 1 9.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 AAS53271.1 - 0.041 13.7 6.4 0.85 9.6 0.0 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 AAS53271.1 - 0.043 13.6 4.7 0.074 12.8 0.1 3.0 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 TPR_19 PF14559.1 AAS53271.1 - 0.1 12.9 13.9 1.5 9.1 0.3 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 AAS53271.1 - 0.13 12.2 1.8 0.54 10.2 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 AAS53271.1 - 1.8 8.7 8.2 2 8.6 0.1 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 AAS53271.1 - 2.9 8.7 10.1 6.3 7.7 0.3 4.8 5 1 0 5 5 4 0 Tetratricopeptide repeat DEAD PF00270.24 AAS53272.1 - 1.5e-30 105.9 0.1 4.1e-30 104.5 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS53272.1 - 7.4e-16 57.7 0.1 7.5e-15 54.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AAS53272.1 - 3.9e-08 32.4 0.1 5.6e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 AAS53272.1 - 1.8e-06 27.8 0.0 3.7e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AAS53272.1 - 0.012 15.8 0.1 0.12 12.4 0.0 2.5 1 1 1 2 2 2 0 AAA domain Pkinase PF00069.20 AAS53273.1 - 1.9e-70 237.0 0.0 2.5e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53273.1 - 6.6e-44 149.9 0.0 8.7e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS53273.1 - 7.5e-07 28.3 0.0 1.8e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AAS53273.1 - 0.075 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SET PF00856.23 AAS53274.2 - 2e-08 34.6 0.0 4.3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 SET domain DinB_2 PF12867.2 AAS53274.2 - 0.016 15.5 0.5 4 7.8 0.1 2.5 2 0 0 2 2 2 0 DinB superfamily Fn3-like PF14310.1 AAS53274.2 - 0.033 14.1 0.2 0.072 13.0 0.1 1.6 1 0 0 1 1 1 0 Fibronectin type III-like domain Radical_SAM PF04055.16 AAS53275.1 - 1e-21 77.8 0.0 3.7e-21 76.0 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Wyosine_form PF08608.7 AAS53275.1 - 1.7e-21 76.0 0.0 5.1e-21 74.5 0.0 1.9 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 AAS53275.1 - 5e-09 36.2 0.0 1.3e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin Glycos_transf_1 PF00534.15 AAS53276.1 - 1.7e-31 108.9 0.1 3.5e-16 59.0 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AAS53276.1 - 3.1e-07 30.2 0.0 8.9e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 AAS53276.1 - 2.1e-05 24.6 0.0 0.00049 20.2 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 AAS53276.1 - 0.0026 17.8 0.0 0.0062 16.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain SCA7 PF08313.7 AAS53277.1 - 8.3e-34 115.0 2.3 8.3e-34 115.0 1.6 2.5 3 1 1 4 4 4 1 SCA7, zinc-binding domain AAA_23 PF13476.1 AAS53277.1 - 7.2 6.8 14.3 6.1 7.1 7.0 2.1 2 0 0 2 2 2 0 AAA domain GDPD PF03009.12 AAS53278.1 - 1.2e-29 103.6 0.2 4e-29 101.9 0.2 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Glyoxalase_4 PF13669.1 AAS53278.1 - 0.0022 17.9 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GDPD_2 PF13653.1 AAS53278.1 - 0.083 13.1 0.6 1.5 9.0 0.1 2.6 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Flocculin PF00624.13 AAS53279.2 - 0 1114.7 1218.3 3.7e-14 52.2 15.6 44.0 42 4 2 44 44 44 31 Flocculin repeat DUF605 PF04652.11 AAS53279.2 - 0.086 12.2 43.2 0.23 10.8 29.9 1.8 1 0 0 1 1 1 0 Vta1 like Peptidase_U57 PF05582.7 AAS53279.2 - 5.6 5.8 6.0 8.5 5.2 1.0 4.1 2 0 0 2 2 2 0 YabG peptidase U57 Flocculin PF00624.13 AAS53280.2 - 5e-63 208.7 186.3 2.9e-15 55.8 14.8 8.9 9 0 0 9 9 9 6 Flocculin repeat PA14_2 PF10528.4 AAS53280.2 - 7.7e-13 48.3 0.8 4.3e-12 45.9 0.6 2.4 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.7 AAS53280.2 - 1.3e-10 41.1 0.0 4.2e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 PA14 domain Pkinase PF00069.20 AAS53281.1 - 1.3e-40 139.2 0.1 2.5e-40 138.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53281.1 - 1.1e-14 54.1 0.0 2.5e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AAS53281.1 - 0.0038 16.9 0.4 0.087 12.5 0.0 2.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 AAS53281.1 - 0.044 12.5 0.9 0.058 12.1 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 AAS53282.1 - 7.8e-69 231.7 0.0 9.1e-69 231.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53282.1 - 9.2e-39 133.0 0.0 1.2e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS53282.1 - 1.3e-05 24.3 0.0 2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 AAS53282.1 - 0.018 14.3 0.1 0.075 12.3 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.18 AAS53282.1 - 0.042 13.5 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 AAS53282.1 - 0.043 12.8 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 AAS53282.1 - 0.15 10.9 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_L12 PF00542.14 AAS53283.1 - 5e-20 71.2 12.3 5.6e-20 71.1 7.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain DUF2267 PF10025.4 AAS53283.1 - 0.0015 18.5 0.1 0.0059 16.6 0.1 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2267) Ribosomal_60s PF00428.14 AAS53283.1 - 1.2 9.6 21.1 0.036 14.4 6.9 2.4 1 1 1 2 2 2 0 60s Acidic ribosomal protein RNA_POL_M_15KD PF02150.11 AAS53284.1 - 5.9e-15 54.6 3.4 5.9e-15 54.6 2.4 2.3 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 AAS53284.1 - 1.2e-13 50.4 15.0 1.8e-13 49.8 1.1 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 AAS53284.1 - 0.00096 19.4 2.8 0.015 15.5 0.2 2.2 2 0 0 2 2 2 1 Restriction alleviation protein Lar DUF2387 PF09526.5 AAS53284.1 - 0.0034 17.2 2.4 0.23 11.3 0.1 2.3 2 0 0 2 2 2 1 Probable metal-binding protein (DUF2387) DZR PF12773.2 AAS53284.1 - 0.065 13.0 8.7 0.13 12.0 0.6 2.6 2 1 0 2 2 2 0 Double zinc ribbon Rubredoxin PF00301.15 AAS53284.1 - 0.1 12.4 3.8 55 3.7 0.0 3.9 4 0 0 4 4 4 0 Rubredoxin C1_4 PF07975.7 AAS53284.1 - 0.2 11.7 10.6 0.44 10.5 0.8 3.0 2 1 1 3 3 3 0 TFIIH C1-like domain GFA PF04828.9 AAS53284.1 - 0.26 11.2 4.4 4 7.4 0.2 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2296 PF10058.4 AAS53284.1 - 0.42 10.3 5.6 0.66 9.7 0.2 2.5 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) IBR PF01485.16 AAS53284.1 - 0.66 9.8 7.2 1.7 8.5 0.4 2.7 2 1 0 2 2 2 0 IBR domain Zn_Tnp_IS1595 PF12760.2 AAS53284.1 - 1.1 9.1 12.7 5.6 6.8 3.0 2.9 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Rpr2 PF04032.11 AAS53284.1 - 1.4 8.8 5.5 12 5.8 1.0 2.7 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF3795 PF12675.2 AAS53284.1 - 2.5 8.3 5.1 4.8 7.4 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3795) HypA PF01155.14 AAS53284.1 - 2.5 7.7 7.9 18 5.0 3.7 2.8 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-CHY PF05495.7 AAS53284.1 - 2.7 8.2 9.3 1.4 9.0 0.7 2.4 2 1 1 3 3 3 0 CHY zinc finger zf-UBP PF02148.14 AAS53284.1 - 3.3 7.8 6.0 2.7 8.1 0.3 2.3 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Zn-ribbon_8 PF09723.5 AAS53284.1 - 4.4 7.3 13.2 6.6 6.7 0.0 3.8 3 1 1 4 4 4 0 Zinc ribbon domain Cytochrom_NNT PF03264.9 AAS53284.1 - 5 6.5 7.7 0.14 11.5 0.4 2.0 2 1 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region AFT PF08731.6 AAS53285.1 - 1.2e-48 163.9 0.0 2.4e-48 162.9 0.0 1.5 1 0 0 1 1 1 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 AAS53285.1 - 2.2e-05 23.9 1.4 0.028 14.0 0.1 2.5 2 0 0 2 2 2 2 MuDR family transposase HSF_DNA-bind PF00447.12 AAS53287.2 - 1.5e-35 121.4 2.5 3.1e-35 120.4 1.7 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding BLOC1_2 PF10046.4 AAS53287.2 - 1.1 9.4 3.7 5.2 7.2 0.8 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med9 PF07544.8 AAS53288.2 - 0.0022 17.7 2.6 0.0023 17.6 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 CRISPR_Cse1 PF09481.5 AAS53288.2 - 0.0057 15.4 0.1 0.009 14.8 0.1 1.3 1 0 0 1 1 1 1 CRISPR-associated protein Cse1 (CRISPR_cse1) Lge1 PF11488.3 AAS53288.2 - 0.46 10.6 2.6 0.72 10.0 0.4 2.0 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DUF1771 PF08590.5 AAS53289.1 - 5.4e-23 80.7 12.8 9e-23 80.0 8.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 AAS53289.1 - 4.2e-15 55.6 0.1 9.5e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Smr domain Dispanin PF04505.7 AAS53289.1 - 0.069 12.7 1.3 0.34 10.4 0.3 2.1 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Ribosomal_L30_N PF08079.7 AAS53290.1 - 9e-20 70.4 18.1 1.6e-19 69.6 12.5 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 AAS53290.1 - 1.2e-19 69.5 1.8 2.3e-19 68.7 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e AA_permease_2 PF13520.1 AAS53291.1 - 8.9e-53 179.3 43.0 1.1e-52 179.0 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AAS53291.1 - 1.7e-20 72.8 39.1 2.2e-20 72.4 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease DEAD PF00270.24 AAS53292.1 - 2.6e-51 173.4 0.1 2.2e-49 167.2 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS53292.1 - 5.1e-30 103.1 0.0 2.9e-28 97.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 AAS53292.1 - 0.0002 19.8 0.1 0.0002 19.8 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) CMS1 PF14617.1 AAS53292.1 - 0.013 14.5 0.0 0.013 14.5 0.0 2.9 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 AAS53292.1 - 0.13 12.3 1.2 0.53 10.4 0.4 2.3 2 1 0 2 2 2 0 AAA domain FA_desaturase PF00487.19 AAS53293.1 - 1.8e-39 135.7 23.2 2.6e-39 135.2 16.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 AAS53293.1 - 1.2e-12 47.3 0.2 2e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TLD PF07534.11 AAS53294.2 - 7.3e-30 103.7 0.0 9.6e-30 103.3 0.0 1.2 1 0 0 1 1 1 1 TLD KxDL PF10241.4 AAS53295.1 - 1.1e-11 44.4 0.5 1.6e-11 43.9 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein IncA PF04156.9 AAS53295.1 - 0.05 13.1 1.8 0.062 12.8 1.3 1.4 1 1 0 1 1 1 0 IncA protein DUF3540 PF12059.3 AAS53295.1 - 0.072 12.7 1.3 0.1 12.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) DUF3407 PF11887.3 AAS53295.1 - 0.083 12.1 0.3 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) Adaptin_N PF01602.15 AAS53296.1 - 4.2e-114 381.7 16.8 5.7e-114 381.3 11.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 AAS53296.1 - 6.6e-06 26.3 0.0 0.28 11.4 0.0 5.2 2 2 2 4 4 4 1 HEAT repeats HEAT PF02985.17 AAS53296.1 - 0.00054 19.8 1.5 14 6.0 0.0 6.2 7 0 0 7 7 7 1 HEAT repeat Arm PF00514.18 AAS53296.1 - 0.0086 15.8 0.0 63 3.6 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Rad9 PF04139.8 AAS53297.1 - 3.1e-11 42.8 0.7 1.5e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Rad9 MPC PF03650.8 AAS53298.1 - 1.1e-40 138.2 0.1 1.2e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) NUFIP1 PF10453.4 AAS53299.1 - 3.8e-17 61.5 0.1 7.4e-17 60.6 0.1 1.5 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) FHA PF00498.21 AAS53300.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain DUF544 PF04424.8 AAS53301.2 - 7e-22 77.5 0.0 1.3e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) RRM_1 PF00076.17 AAS53302.1 - 3.8e-11 42.4 0.2 8.1e-11 41.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS53302.1 - 4.7e-07 29.6 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS53302.1 - 0.0013 18.5 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 AAS53304.1 - 7.9e-18 64.5 0.0 1.7e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53304.1 - 1.8e-12 46.9 0.0 4e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase MBOAT PF03062.14 AAS53305.2 - 5.5e-55 186.7 21.0 5.5e-55 186.7 14.5 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SNase PF00565.12 AAS53306.1 - 1.6e-22 79.8 0.0 2.4e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MAD PF05557.8 AAS53307.2 - 1.1e-23 83.3 73.1 3.2e-23 81.7 50.6 1.7 1 1 0 1 1 1 1 Mitotic checkpoint protein UQ_con PF00179.21 AAS53308.1 - 4.7e-16 58.4 0.0 5.3e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AAS53308.1 - 0.014 15.2 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain NAD_kinase PF01513.16 AAS53309.1 - 3.6e-50 170.3 0.0 4.6e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 AAS53309.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain MF_alpha_N PF05436.6 AAS53310.1 - 7.4e-10 38.3 0.0 8.6e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus RRM_6 PF14259.1 AAS53311.2 - 6.2e-29 99.7 1.1 2.8e-07 30.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AAS53311.2 - 1.6e-28 98.1 2.4 1.4e-07 31.0 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS53311.2 - 2.3e-22 78.5 2.6 1e-06 28.5 0.1 4.7 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AAS53311.2 - 0.0077 16.0 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 AAS53311.2 - 0.0078 15.9 0.0 0.45 10.3 0.0 2.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif ParA PF10609.4 AAS53312.2 - 1.5e-34 117.6 0.0 5.4e-34 115.9 0.0 1.9 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 AAS53312.2 - 3.2e-16 59.3 0.0 4.8e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 AAS53312.2 - 2.3e-06 27.6 0.0 7.3e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 AAS53312.2 - 2.7e-05 23.3 0.0 5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 AAS53312.2 - 3.3e-05 23.1 1.7 0.00014 21.0 0.4 2.1 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 AAS53312.2 - 0.019 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain YhjQ PF06564.7 AAS53312.2 - 0.082 12.2 0.1 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 YhjQ protein DUF258 PF03193.11 AAS53312.2 - 0.083 12.0 0.1 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Nup96 PF12110.3 AAS53313.1 - 3.2e-59 200.4 0.8 1.7e-58 198.0 0.1 2.1 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.9 AAS53313.1 - 1.3e-50 170.8 0.0 2.6e-50 169.8 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 AAS53313.1 - 8.4e-14 51.7 98.1 9.7e-09 35.4 25.2 4.4 2 1 2 4 4 4 2 Nucleoporin FG repeat region Spc7 PF08317.6 AAS53314.1 - 6e-101 337.3 12.4 1e-100 336.5 8.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_N PF15402.1 AAS53314.1 - 0.00038 18.6 11.4 0.024 12.6 0.0 2.6 2 1 0 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 Prefoldin_2 PF01920.15 AAS53314.1 - 0.013 15.3 1.3 0.013 15.3 0.9 2.9 3 0 0 3 3 3 0 Prefoldin subunit NPV_P10 PF05531.7 AAS53314.1 - 0.065 13.4 5.2 0.93 9.7 0.4 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.3 AAS53314.1 - 0.53 10.0 13.8 0.46 10.2 4.3 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 AAS53314.1 - 1.9 8.8 9.9 16 5.8 1.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 AAS53314.1 - 3.3 7.8 10.6 1.6 8.8 5.3 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1319 PF07028.6 AAS53314.1 - 4.1 7.6 15.1 0.43 10.7 5.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) FlaC_arch PF05377.6 AAS53314.1 - 5.3 7.0 9.9 3.2 7.7 2.0 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ribosomal_L36 PF00444.13 AAS53315.1 - 1.1e-20 73.2 10.1 1.6e-20 72.7 7.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.12 AAS53315.1 - 0.2 10.9 1.8 0.28 10.5 1.3 1.2 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family WD40 PF00400.27 AAS53316.1 - 9.5e-30 101.3 25.7 3.6e-10 39.3 0.2 11.4 12 0 0 12 12 12 6 WD domain, G-beta repeat Nup160 PF11715.3 AAS53316.1 - 0.00024 19.3 7.5 0.0085 14.2 0.4 3.2 2 1 0 3 3 3 3 Nucleoporin Nup120/160 UCH_1 PF13423.1 AAS53317.2 - 1e-49 169.5 2.8 1.6e-49 168.9 1.9 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 AAS53317.2 - 2e-26 93.2 0.0 4e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 AAS53317.2 - 3.9e-05 22.9 3.7 0.00037 19.7 2.5 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 AAS53317.2 - 0.023 14.5 0.5 2.2 8.3 0.1 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat TCO89 PF10452.4 AAS53318.2 - 9e-226 751.5 11.9 1e-225 751.3 8.3 1.0 1 0 0 1 1 1 1 TORC1 subunit TCO89 Sec1 PF00995.18 AAS53319.2 - 3.1e-132 442.0 0.8 3.5e-132 441.9 0.6 1.0 1 0 0 1 1 1 1 Sec1 family PHD PF00628.24 AAS53320.1 - 2.5e-11 43.0 6.7 4.4e-11 42.2 4.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 AAS53320.1 - 0.14 11.5 5.2 0.26 10.6 3.6 1.4 1 0 0 1 1 1 0 PHD-finger FAM163 PF15069.1 AAS53320.1 - 0.68 10.5 2.8 0.85 10.1 0.2 2.3 2 0 0 2 2 2 0 FAM163 family Metallophos PF00149.23 AAS53321.1 - 1e-39 136.0 0.0 1.4e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RRM_1 PF00076.17 AAS53322.1 - 1.1e-15 56.9 0.0 1.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS53322.1 - 1.1e-12 47.7 0.0 1.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS53322.1 - 3e-09 36.6 0.0 4.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.17 AAS53322.1 - 0.018 14.0 0.1 0.018 14.0 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Homeobox_KN PF05920.6 AAS53323.1 - 6.4e-18 64.1 0.9 1.3e-17 63.1 0.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 AAS53323.1 - 1.4e-06 27.7 0.5 3.2e-06 26.6 0.3 1.6 1 0 0 1 1 1 1 Homeobox domain Arrestin_N PF00339.24 AAS53324.2 - 0.0091 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DAHP_synth_1 PF00793.15 AAS53325.1 - 8.1e-102 339.5 0.0 1e-101 339.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family His_biosynth PF00977.16 AAS53326.1 - 4.9e-46 156.8 0.0 2.6e-45 154.4 0.0 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 AAS53326.1 - 6.4e-29 100.7 0.0 9.5e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 AAS53326.1 - 1.6e-08 34.2 0.0 3.7e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 AAS53326.1 - 1.5e-06 28.0 0.0 0.00024 20.8 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family ThiG PF05690.9 AAS53326.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Peptidase_S51 PF03575.12 AAS53326.1 - 0.039 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 DJ-1_PfpI PF01965.19 AAS53326.1 - 0.1 12.0 0.0 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 DJ-1/PfpI family RCC1 PF00415.13 AAS53327.1 - 1.2e-65 217.5 0.0 4.5e-13 49.1 0.0 7.4 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AAS53327.1 - 4.8e-38 127.9 20.9 6.6e-09 35.1 0.0 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Bystin PF05291.6 AAS53328.2 - 8.8e-126 418.8 0.0 8.8e-126 418.8 0.0 1.6 2 0 0 2 2 2 1 Bystin DUF3090 PF11290.3 AAS53328.2 - 0.94 8.9 4.8 1.9 7.9 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) Use1 PF09753.4 AAS53329.2 - 1.4e-07 31.2 0.1 2.2e-07 30.5 0.1 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 Sec20 PF03908.8 AAS53329.2 - 0.039 13.6 0.4 0.088 12.5 0.3 1.6 1 0 0 1 1 1 0 Sec20 DUF21 PF01595.15 AAS53329.2 - 0.06 12.6 0.1 0.088 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF21 MMR_HSR1 PF01926.18 AAS53330.2 - 6.3e-18 64.8 0.3 4e-15 55.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 AAS53330.2 - 4.9e-08 32.4 1.1 6.6e-06 25.4 0.0 2.6 2 1 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 AAS53330.2 - 0.00059 19.6 0.6 0.0098 15.7 0.1 2.7 2 1 0 2 2 2 1 Dynamin family DUF258 PF03193.11 AAS53330.2 - 0.00081 18.6 0.0 0.0018 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 AAS53330.2 - 0.012 16.0 0.5 0.068 13.6 0.1 2.3 2 0 0 2 2 2 0 Miro-like protein AIG1 PF04548.11 AAS53330.2 - 0.018 14.1 0.0 0.04 13.0 0.0 1.5 1 0 0 1 1 1 0 AIG1 family WD40 PF00400.27 AAS53331.1 - 1e-06 28.3 4.4 0.18 11.7 0.1 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ PF01011.16 AAS53331.1 - 0.00014 21.2 3.1 0.0031 16.9 0.2 3.1 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.1 AAS53331.1 - 0.0019 17.7 1.5 1.1 8.6 0.0 2.9 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 AAS53331.1 - 3 8.2 16.8 49 4.3 0.0 5.9 6 1 0 6 6 6 0 PQQ-like domain SNF2_N PF00176.18 AAS53332.1 - 3.4e-80 269.0 0.2 5.9e-80 268.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 AAS53332.1 - 2.8e-41 139.9 2.2 2.8e-41 139.9 1.5 2.5 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 AAS53332.1 - 3.4e-34 117.6 0.4 3.4e-34 117.6 0.3 4.4 5 0 0 5 5 5 1 HAND Helicase_C PF00271.26 AAS53332.1 - 1.6e-15 56.6 0.0 4.4e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 AAS53332.1 - 6.1e-12 44.9 0.0 1.5e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 AAS53332.1 - 2.6e-08 33.9 2.7 7.8e-07 29.0 0.0 4.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AAS53332.1 - 6.8e-05 22.4 0.0 0.00017 21.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 AAS53332.1 - 0.015 15.1 0.5 0.075 12.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain DEAD_2 PF06733.10 AAS53332.1 - 0.019 14.3 0.1 0.043 13.2 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 GSHPx PF00255.14 AAS53333.1 - 5.1e-46 154.5 0.3 6.7e-46 154.1 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 AAS53333.1 - 8.6e-08 31.9 0.3 2.5e-07 30.3 0.2 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AAS53333.1 - 3.3e-07 29.9 0.1 1e-06 28.3 0.1 1.8 1 1 0 1 1 1 1 Redoxin UPF0728 PF15092.1 AAS53333.1 - 0.025 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0728 DUF4174 PF13778.1 AAS53333.1 - 0.043 13.9 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) WD40 PF00400.27 AAS53334.1 - 6.5e-34 114.5 17.5 2.7e-08 33.3 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat YmzC PF14157.1 AAS53334.1 - 0.0032 17.2 0.0 0.039 13.7 0.0 2.6 3 0 0 3 3 3 1 YmzC-like protein Apc4_WD40 PF12894.2 AAS53334.1 - 0.039 13.4 0.0 8.6 5.9 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Glycos_transf_4 PF00953.16 AAS53335.1 - 3.3e-30 104.9 11.1 3.3e-30 104.9 7.7 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 4 DUF1279 PF06916.8 AAS53335.1 - 0.17 12.2 1.6 9.4 6.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) Phtf-FEM1B_bdg PF12129.3 AAS53335.1 - 0.21 10.9 4.2 0.4 10.0 2.9 1.6 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor HD_3 PF13023.1 AAS53336.2 - 2e-37 128.4 0.1 2.5e-37 128.1 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 AAS53336.2 - 1e-05 25.5 0.4 2.6e-05 24.2 0.3 1.7 1 1 0 1 1 1 1 HD domain HD_2 PF12917.2 AAS53336.2 - 0.063 13.0 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Ribosomal_L18e PF00828.14 AAS53337.1 - 1.6e-35 122.2 0.2 2.3e-35 121.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Sugar_tr PF00083.19 AAS53338.2 - 9.2e-98 327.7 13.8 1.2e-97 327.3 9.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AAS53338.2 - 3.2e-29 101.7 23.3 3.2e-29 101.7 16.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 AAS53338.2 - 8.3 6.5 16.7 0.035 14.1 1.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Zn_clus PF00172.13 AAS53339.1 - 2.2e-10 40.2 3.5 6.1e-10 38.8 2.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA_bind PF01588.15 AAS53340.1 - 3.5e-27 94.0 0.1 6.7e-27 93.1 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain DUF236 PF03057.9 AAS53340.1 - 0.33 10.9 12.4 0.21 11.5 6.9 1.8 2 0 0 2 2 2 0 Protein of unknown function MDMPI_N PF11716.3 AAS53340.1 - 3.7 7.9 10.6 11 6.4 7.3 1.8 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain PAS PF00989.19 AAS53341.2 - 7.4e-15 54.7 0.0 1.2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 AAS53341.2 - 3.4e-06 26.8 10.4 6.3e-06 26.0 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.1 AAS53341.2 - 0.024 14.9 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.5 AAS53341.2 - 0.13 12.2 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold EF-hand_7 PF13499.1 AAS53342.1 - 9.2e-13 48.1 0.5 1.5e-07 31.4 0.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AAS53342.1 - 7.5e-11 40.9 0.5 0.00056 19.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.1 AAS53342.1 - 1.2e-09 37.9 0.0 0.0021 17.9 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 AAS53342.1 - 6.4e-08 31.3 4.6 0.0008 18.5 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 AAS53342.1 - 3.5e-06 26.5 2.2 5e-05 22.8 0.4 2.8 2 1 1 3 3 3 1 EF-hand domain pair FliG_N PF14842.1 AAS53342.1 - 0.055 13.5 0.1 0.081 13.0 0.1 1.2 1 0 0 1 1 1 0 FliG N-terminal domain EF-hand_5 PF13202.1 AAS53342.1 - 0.27 10.6 1.5 1.7 8.1 0.1 2.4 2 0 0 2 2 2 0 EF hand DUF413 PF04219.7 AAS53344.2 - 0.099 12.4 2.1 3.6 7.3 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF DEAD PF00270.24 AAS53345.2 - 1.5e-43 148.1 0.0 5e-43 146.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS53345.2 - 9.2e-16 57.4 0.0 2.2e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AAS53345.2 - 0.0022 16.8 0.0 0.0034 16.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Pox_MCEL PF03291.11 AAS53346.1 - 8.2e-97 324.0 0.4 1.1e-96 323.6 0.2 1.2 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.7 AAS53346.1 - 7.1e-08 32.8 0.3 2.8e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS53346.1 - 2.4e-07 31.3 0.0 4.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AAS53346.1 - 3e-07 30.8 0.1 8e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AAS53346.1 - 6.8e-07 29.1 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS53346.1 - 4.9e-06 26.2 0.1 4.9e-06 26.2 0.1 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AAS53346.1 - 1.1e-05 25.7 0.0 2.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 AAS53346.1 - 0.0023 16.9 0.0 0.0049 15.8 0.0 1.5 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 AAS53346.1 - 0.0028 16.7 0.0 0.0076 15.3 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 AAS53346.1 - 0.0049 16.9 0.0 0.0096 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF4603 PF15376.1 AAS53346.1 - 0.0068 13.6 4.8 0.0089 13.2 3.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4603) Methyltransf_15 PF09445.5 AAS53346.1 - 0.0069 15.9 1.6 0.077 12.5 0.0 2.2 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase DUF1013 PF06242.6 AAS53346.1 - 0.03 14.3 1.0 0.058 13.3 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) MetW PF07021.7 AAS53346.1 - 0.034 13.5 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.14 AAS53346.1 - 0.079 12.4 0.1 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AA_permease PF00324.16 AAS53347.1 - 1.1e-47 162.5 36.3 1.1e-47 162.5 25.2 1.8 2 0 0 2 2 2 1 Amino acid permease CUE PF02845.11 AAS53348.1 - 9.7e-10 37.7 0.3 2.2e-09 36.5 0.2 1.7 1 0 0 1 1 1 1 CUE domain WD40 PF00400.27 AAS53350.1 - 4e-14 51.8 11.6 0.00045 19.9 0.0 5.9 6 1 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 AAS53350.1 - 0.00052 19.7 0.1 0.012 15.2 0.0 2.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Rax2 PF12768.2 AAS53350.1 - 0.0024 17.1 0.1 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DASH_Dad3 PF08656.5 AAS53351.1 - 5.7e-28 96.4 0.2 6.2e-28 96.3 0.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 Ste5_C PF12194.3 AAS53351.1 - 0.064 12.8 0.0 0.074 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein kinase Fus3-binding DUF1546 PF07571.8 AAS53352.1 - 8.6e-32 109.1 0.0 2.2e-31 107.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 AAS53352.1 - 2.6e-27 94.5 0.2 5.8e-27 93.4 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 AAS53352.1 - 0.0037 17.3 0.1 0.022 14.8 0.1 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 AAS53352.1 - 0.023 14.4 0.1 0.077 12.7 0.0 1.9 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.18 AAS53352.1 - 0.033 14.2 0.6 0.75 9.9 0.0 2.9 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 AAS53352.1 - 0.038 14.1 3.1 2.4 8.4 0.0 3.3 4 0 0 4 4 4 0 Kinetochore component CENP-S CLASP_N PF12348.3 AAS53352.1 - 0.053 12.8 0.7 1.4 8.2 0.1 2.8 3 0 0 3 3 3 0 CLASP N terminal SLD3 PF08639.5 AAS53353.1 - 3.7e-101 339.2 18.2 4.7e-101 338.8 12.6 1.1 1 0 0 1 1 1 1 DNA replication regulator SLD3 KH_1 PF00013.24 AAS53354.1 - 1.9e-35 120.3 5.6 4.5e-13 48.6 2.4 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 AAS53354.1 - 5.1e-29 99.4 7.4 6.2e-12 44.8 1.9 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 AAS53354.1 - 9e-11 41.1 1.1 0.064 12.8 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 AAS53354.1 - 0.018 14.6 4.5 1.8 8.2 0.0 3.1 4 1 0 4 4 4 0 KH domain KH_5 PF13184.1 AAS53354.1 - 0.022 14.5 4.8 4.2 7.2 0.2 3.8 3 1 0 3 3 3 0 NusA-like KH domain BCNT PF07572.7 AAS53355.1 - 1.1e-25 89.3 0.1 3.3e-25 87.8 0.1 1.8 1 0 0 1 1 1 1 Bucentaur or craniofacial development OPT PF03169.10 AAS53356.1 - 2.3e-150 502.0 22.6 2.6e-150 501.8 15.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ABC2_membrane_5 PF13346.1 AAS53356.1 - 0.0049 16.1 2.6 0.0049 16.1 1.8 4.0 4 1 0 4 4 4 1 ABC-2 family transporter protein CBS PF00571.23 AAS53357.1 - 6.3e-29 99.5 2.9 1.2e-12 47.3 0.1 4.2 4 0 0 4 4 4 4 CBS domain HTH_9 PF08221.6 AAS53357.1 - 0.4 10.5 2.3 3 7.8 0.1 3.0 4 0 0 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain WD40 PF00400.27 AAS53358.1 - 2e-23 81.3 14.4 1.5e-08 34.2 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 AAS53358.1 - 6.5e-06 25.9 0.9 0.017 14.8 0.1 2.7 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 AAS53358.1 - 0.1 10.7 0.1 7.8 4.5 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3312) tRNA_int_endo PF01974.12 AAS53360.2 - 9.9e-13 47.7 0.1 1.7e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain LisH PF08513.6 AAS53360.2 - 0.0055 16.4 1.0 0.012 15.3 0.7 1.6 1 0 0 1 1 1 1 LisH E1-E2_ATPase PF00122.15 AAS53361.1 - 8.9e-60 201.5 0.4 1.7e-59 200.7 0.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AAS53361.1 - 1.5e-39 135.4 2.7 1.5e-39 135.4 1.9 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AAS53361.1 - 3.8e-24 86.3 0.0 7.4e-18 65.7 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AAS53361.1 - 3e-13 49.5 0.0 7.3e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AAS53361.1 - 4.6e-13 49.7 0.0 2.4e-12 47.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AAS53361.1 - 1.9e-12 46.4 0.0 4.8e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AAS53361.1 - 0.0061 16.1 1.3 0.016 14.8 0.5 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sporozoite_P67 PF05642.6 AAS53362.1 - 0.046 11.5 3.8 0.061 11.1 2.1 1.5 1 1 1 2 2 2 0 Sporozoite P67 surface antigen Reo_sigmaC PF04582.7 AAS53362.1 - 0.49 9.5 5.5 0.47 9.5 2.6 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 AAS53362.1 - 0.66 9.8 4.5 0.27 11.0 0.1 2.3 3 0 0 3 3 3 0 Tropomyosin like Flagellin_C PF00700.16 AAS53362.1 - 0.66 10.1 6.4 1.1 9.4 0.9 3.3 2 2 1 3 3 3 0 Bacterial flagellin C-terminal helical region ERp29 PF07749.7 AAS53362.1 - 3.4 8.3 5.7 21 5.8 0.1 3.1 2 2 1 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain WD40 PF00400.27 AAS53363.1 - 6.9e-16 57.4 2.4 2.8e-06 26.9 0.3 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Rep_fac-A_C PF08646.5 AAS53364.1 - 4.4e-54 182.1 13.5 3.2e-53 179.3 0.8 3.6 3 0 0 3 3 3 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 AAS53364.1 - 3.6e-17 61.9 3.6 2e-09 37.1 0.0 5.3 5 0 0 5 5 5 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 AAS53364.1 - 0.0048 16.6 0.8 0.014 15.1 0.0 2.2 3 0 0 3 3 3 1 Replication factor-A protein 1, N-terminal domain AIF_C PF14721.1 AAS53364.1 - 0.01 16.0 4.1 0.031 14.5 2.9 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Gag_spuma PF03276.9 AAS53364.1 - 0.072 11.4 19.8 0.13 10.6 13.7 1.3 1 0 0 1 1 1 0 Spumavirus gag protein PAT1 PF09770.4 AAS53364.1 - 0.078 11.2 27.1 0.11 10.6 18.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 AAS53364.1 - 0.079 12.6 13.2 0.17 11.5 9.2 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.5 AAS53364.1 - 0.086 11.0 37.9 0.12 10.4 26.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4557 PF15101.1 AAS53364.1 - 0.17 11.7 16.1 0.4 10.4 11.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Pex14_N PF04695.8 AAS53364.1 - 2 8.4 17.4 6 6.9 12.0 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Band_3_cyto PF07565.8 AAS53364.1 - 8.4 5.8 13.3 16 4.9 9.2 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain WD40 PF00400.27 AAS53365.2 - 6.9e-32 108.1 2.4 3.6e-06 26.6 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 AAS53365.2 - 0.00023 20.9 0.1 0.65 9.6 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 AAS53366.1 - 3.5e-16 58.3 2.9 7.1e-07 28.8 1.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 AAS53366.1 - 0.00039 18.8 0.0 0.001 17.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.6 AAS53366.1 - 0.0078 15.9 0.0 0.097 12.3 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 AAS53366.1 - 0.056 12.9 0.0 2.4 7.7 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.5 AAS53366.1 - 0.16 10.3 0.0 2.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal EMP24_GP25L PF01105.19 AAS53367.1 - 2.1e-47 161.1 0.1 2.5e-47 160.9 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD B-block_TFIIIC PF04182.7 AAS53370.2 - 4.3e-18 64.9 0.0 1.1e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC N6-adenineMlase PF10237.4 AAS53371.1 - 3.4e-60 202.3 0.1 4.6e-60 201.9 0.1 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase 3Beta_HSD PF01073.14 AAS53372.1 - 7.4e-83 277.4 0.0 9e-83 277.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AAS53372.1 - 4.4e-29 101.5 0.0 5.5e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AAS53372.1 - 1.9e-16 59.7 0.0 6.5e-16 58.0 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 AAS53372.1 - 2.4e-12 46.3 0.0 3.9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 AAS53372.1 - 6.6e-09 36.0 0.0 1e-08 35.3 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 AAS53372.1 - 2.4e-07 29.9 0.0 6.2e-07 28.5 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 AAS53372.1 - 0.0036 16.5 0.0 0.0056 15.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 AAS53372.1 - 0.0045 16.9 0.0 0.014 15.3 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AAS53372.1 - 0.015 14.9 0.0 0.095 12.3 0.0 2.1 1 1 0 1 1 1 0 KR domain Vps8 PF12816.2 AAS53373.1 - 6.6e-62 208.2 11.0 1.9e-60 203.5 2.6 2.7 3 0 0 3 3 3 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 AAS53373.1 - 2e-07 30.6 5.1 4.2e-05 23.1 0.0 3.4 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-C3HC4 PF00097.20 AAS53373.1 - 0.0052 16.4 0.3 0.0052 16.4 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AAS53373.1 - 0.01 15.6 0.6 0.01 15.6 0.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 AAS53373.1 - 0.012 15.2 1.1 0.057 13.1 0.8 2.3 1 1 0 1 1 1 0 zinc-RING finger domain Lgl_C PF08596.5 AAS53373.1 - 0.017 13.5 0.0 0.052 12.0 0.0 1.7 1 1 1 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal VWA_3 PF13768.1 AAS53373.1 - 0.019 14.6 0.0 0.084 12.5 0.0 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain EF1_GNE PF00736.14 AAS53374.1 - 5.4e-30 102.9 2.9 5.4e-30 102.9 2.0 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 AAS53374.1 - 3.1e-13 49.6 4.2 3.1e-13 49.6 2.9 3.1 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region FAD_binding_5 PF00941.16 AAS53374.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase GST_C PF00043.20 AAS53374.1 - 0.078 12.9 1.9 0.54 10.2 0.1 2.6 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF3752 PF12572.3 AAS53374.1 - 0.095 12.8 5.7 0.14 12.2 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) CbiN PF02553.10 AAS53374.1 - 0.83 9.6 3.2 1.7 8.7 0.2 2.3 2 0 0 2 2 2 0 Cobalt transport protein component CbiN SNF5 PF04855.7 AAS53375.1 - 5.4e-66 222.5 3.3 2.9e-63 213.5 2.3 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 PepX_N PF09168.5 AAS53375.1 - 0.16 12.2 4.4 0.35 11.0 0.9 2.2 1 1 0 2 2 2 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal CHD5 PF04420.9 AAS53377.1 - 3.1e-44 150.4 0.4 4.4e-44 149.9 0.3 1.2 1 0 0 1 1 1 1 CHD5-like protein GAPT PF11770.3 AAS53377.1 - 0.059 13.0 0.2 6.1 6.4 0.0 2.2 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) DUF919 PF06034.6 AAS53377.1 - 0.07 12.7 4.0 1 9.0 0.1 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) GED PF02212.13 AAS53377.1 - 0.15 11.9 1.4 0.17 11.8 0.1 1.8 2 0 0 2 2 2 0 Dynamin GTPase effector domain Cortex-I_coil PF09304.5 AAS53377.1 - 1.8 8.6 8.6 0.068 13.2 1.6 1.9 3 0 0 3 3 3 0 Cortexillin I, coiled coil UCH PF00443.24 AAS53378.2 - 4.6e-66 222.6 4.4 1.9e-65 220.6 2.9 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AAS53378.2 - 1.1e-25 90.7 2.6 3.5e-25 89.0 1.8 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 AAS53378.2 - 3.8e-10 40.0 0.0 1e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.15 AAS53378.2 - 0.0031 16.9 4.5 0.013 14.9 3.1 2.2 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger Zn-ribbon_8 PF09723.5 AAS53378.2 - 0.093 12.7 5.7 0.32 10.9 2.0 2.7 2 0 0 2 2 2 0 Zinc ribbon domain BSD PF03909.12 AAS53379.1 - 4.8e-16 58.2 0.2 4.8e-16 58.2 0.1 2.7 3 0 0 3 3 3 1 BSD domain FliT PF05400.8 AAS53379.1 - 2.8 8.4 8.2 1.9 8.9 0.3 3.0 2 1 0 2 2 2 0 Flagellar protein FliT Y_phosphatase2 PF03162.8 AAS53380.1 - 4.5e-55 185.4 0.4 5.4e-55 185.2 0.3 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Phage_glycop_gL PF11108.3 AAS53380.1 - 0.0096 15.8 0.2 0.018 15.0 0.1 1.4 1 0 0 1 1 1 1 Viral glycoprotein L DSPc PF00782.15 AAS53380.1 - 0.035 13.6 0.1 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Asp_protease PF09668.5 AAS53381.1 - 3.3e-53 178.4 0.1 5.3e-53 177.8 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 AAS53381.1 - 2.2e-11 44.0 0.1 5.1e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 AAS53381.1 - 1.3e-07 31.4 0.0 2.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 AAS53381.1 - 2.4e-07 30.7 0.0 4.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 AAS53381.1 - 4.8e-07 29.5 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 AAS53381.1 - 2.2e-05 24.1 0.1 5.8e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain HhH-GPD PF00730.20 AAS53382.1 - 2e-10 40.9 0.0 3.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein COX15-CtaA PF02628.10 AAS53383.1 - 2.9e-103 344.8 5.5 3.5e-103 344.6 3.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein 7TMR-DISM_7TM PF07695.6 AAS53383.1 - 0.57 9.8 9.5 0.12 12.0 0.7 2.8 3 0 0 3 3 3 0 7TM diverse intracellular signalling Lon_C PF05362.8 AAS53384.2 - 6.6e-65 218.2 0.0 1.4e-64 217.2 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 AAS53384.2 - 9.2e-41 139.7 0.9 1.6e-40 139.0 0.0 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 AAS53384.2 - 5.5e-22 78.3 0.0 1.4e-21 77.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AAS53384.2 - 2e-08 34.0 0.0 3.7e-07 29.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 AAS53384.2 - 2.8e-07 30.0 0.0 6.1e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 AAS53384.2 - 1.4e-05 25.0 0.0 4.1e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AAS53384.2 - 2e-05 24.7 0.1 0.0005 20.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 AAS53384.2 - 5.5e-05 22.0 1.0 7.9e-05 21.5 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_17 PF13207.1 AAS53384.2 - 0.00023 21.9 0.0 0.00097 19.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AAS53384.2 - 0.002 17.2 0.0 0.0095 15.0 0.0 2.1 3 0 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 AAS53384.2 - 0.0024 18.1 0.6 0.0068 16.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 AAS53384.2 - 0.0025 17.8 2.5 0.0045 16.9 0.0 2.6 3 2 0 3 3 2 1 AAA ATPase domain AAA_14 PF13173.1 AAS53384.2 - 0.0053 16.6 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 AAS53384.2 - 0.02 14.5 0.1 0.46 10.1 0.0 2.5 1 1 1 2 2 2 0 NTPase HAUS6_N PF14661.1 AAS53384.2 - 0.026 13.8 1.0 0.061 12.6 0.7 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TIP49 PF06068.8 AAS53384.2 - 0.026 13.2 3.9 0.03 13.0 0.0 2.4 3 0 0 3 3 3 0 TIP49 C-terminus DUF258 PF03193.11 AAS53384.2 - 0.027 13.6 0.0 0.057 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 AAS53384.2 - 0.038 13.6 0.1 0.31 10.6 0.1 2.2 1 1 0 1 1 1 0 NACHT domain SKI PF01202.17 AAS53384.2 - 0.043 13.6 0.8 0.26 11.1 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase ATP-synt_ab PF00006.20 AAS53384.2 - 0.051 13.0 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 AAS53384.2 - 0.059 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 AAS53384.2 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 AAS53384.2 - 0.34 11.1 3.3 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain CBFD_NFYB_HMF PF00808.18 AAS53385.1 - 2.2e-25 88.4 0.0 3.1e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AAS53385.1 - 1.2e-05 25.3 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 AAS53385.1 - 0.0095 15.6 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 1 Bromodomain associated TFIID_20kDa PF03847.8 AAS53385.1 - 0.027 14.7 0.4 0.12 12.6 0.1 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Rft-1 PF04506.8 AAS53386.1 - 6.9e-155 516.5 33.4 8e-155 516.3 23.2 1.0 1 0 0 1 1 1 1 Rft protein Exo_endo_phos PF03372.18 AAS53387.1 - 1.5e-19 70.9 0.0 2.2e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 AAS53387.1 - 4.6e-14 52.0 0.0 3.8e-13 49.0 0.0 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 AAS53387.1 - 1.6e-10 40.7 1.1 3.3e-10 39.7 0.8 1.6 1 0 0 1 1 1 1 GRF zinc finger BNR PF02012.15 AAS53389.2 - 3.5e-12 44.1 31.9 0.41 10.6 0.1 12.5 12 0 0 12 12 12 8 BNR/Asp-box repeat BNR_2 PF13088.1 AAS53389.2 - 1.6e-11 44.0 0.1 0.045 13.0 0.2 6.5 5 1 0 5 5 5 4 BNR repeat-like domain CHB_HEX_C_1 PF13290.1 AAS53389.2 - 0.0057 16.3 0.1 0.078 12.7 0.0 2.8 3 0 0 3 3 3 1 Chitobiase/beta-hexosaminidase C-terminal domain Pkinase PF00069.20 AAS53390.1 - 2.5e-71 239.8 0.0 3.2e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53390.1 - 8.2e-31 107.0 0.0 1.1e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS53390.1 - 0.0022 17.0 0.0 0.0076 15.2 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 AAS53390.1 - 0.023 13.7 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AAS53390.1 - 0.03 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Phage_int_SAM_1 PF02899.12 AAS53390.1 - 0.097 12.8 0.0 0.36 11.0 0.0 2.0 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain AcetylCoA_hydro PF02550.10 AAS53391.2 - 3.1e-61 206.6 0.0 6.5e-61 205.5 0.0 1.5 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 AAS53391.2 - 7.8e-39 132.8 0.0 1.5e-38 131.9 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CitF PF04223.7 AAS53391.2 - 0.0013 17.4 0.1 0.0037 16.0 0.0 1.6 2 0 0 2 2 2 1 Citrate lyase, alpha subunit (CitF) Apc1 PF12859.2 AAS53392.1 - 7.6e-12 45.3 0.1 7.6e-12 45.3 0.1 2.6 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 AAS53392.1 - 0.0051 16.9 2.5 0.11 12.7 0.0 3.9 4 0 0 4 4 4 1 Proteasome/cyclosome repeat KdgT PF03812.8 AAS53392.1 - 0.014 14.5 0.3 0.025 13.7 0.2 1.3 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease PS_Dcarbxylase PF02666.10 AAS53393.1 - 3.7e-75 251.6 0.0 4.1e-74 248.2 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase DUF3518 PF12031.3 AAS53393.1 - 0.12 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3518) dCMP_cyt_deam_1 PF00383.17 AAS53394.1 - 1.1e-24 85.9 4.2 1.8e-24 85.3 2.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region FAA_hydrolase PF01557.13 AAS53395.1 - 8.5e-55 185.5 0.0 1.1e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FixP_N PF14715.1 AAS53395.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP bZIP_1 PF00170.16 AAS53396.2 - 5.6e-08 32.6 1.2 5.6e-08 32.6 0.8 1.7 2 0 0 2 2 2 1 bZIP transcription factor Aft1_OSA PF11785.3 AAS53396.2 - 4.3e-07 30.3 0.3 4.3e-07 30.3 0.2 2.6 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 AAS53396.2 - 1.4e-05 24.7 2.0 1.4e-05 24.7 1.4 2.4 2 0 0 2 2 2 1 Basic region leucine zipper CDC45 PF02724.9 AAS53396.2 - 0.11 10.4 3.8 0.16 9.9 2.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_RNApol_7kD PF03604.8 AAS53397.1 - 4.6e-16 57.9 2.1 5.9e-16 57.6 1.5 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 AAS53397.1 - 0.003 17.3 0.4 0.0042 16.8 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 AAS53397.1 - 0.006 16.2 0.2 0.0063 16.1 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family TFIIS_C PF01096.13 AAS53397.1 - 0.0069 16.0 1.0 1.6 8.4 0.1 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Prok-RING_1 PF14446.1 AAS53397.1 - 0.012 15.3 0.5 0.016 14.9 0.4 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 NCD3G PF07562.9 AAS53397.1 - 0.025 14.2 0.2 0.032 13.9 0.1 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR DUF2318 PF10080.4 AAS53397.1 - 0.034 13.9 0.1 0.037 13.8 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) TF_Zn_Ribbon PF08271.7 AAS53397.1 - 0.035 13.4 0.3 4.1 6.7 0.0 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding DUF951 PF06107.6 AAS53397.1 - 0.041 13.3 1.5 0.51 9.8 0.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) FYDLN_acid PF09538.5 AAS53397.1 - 0.057 14.0 0.3 0.069 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DnaJ_CXXCXGXG PF00684.14 AAS53397.1 - 0.057 13.4 0.3 0.064 13.3 0.2 1.3 1 0 0 1 1 1 0 DnaJ central domain C1_1 PF00130.17 AAS53397.1 - 0.1 12.3 0.4 0.15 11.8 0.3 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.1 AAS53397.1 - 0.13 11.5 0.6 0.48 9.7 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 AAS53397.1 - 0.13 11.7 1.2 0.93 9.0 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF4428 PF14471.1 AAS53397.1 - 0.19 11.4 1.6 1.6 8.5 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) DUF2197 PF09963.4 AAS53397.1 - 0.4 10.6 2.3 10 6.1 0.2 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Ribosomal_L40e PF01020.12 AAS53397.1 - 0.43 10.2 3.0 0.56 9.8 2.0 1.2 1 0 0 1 1 1 0 Ribosomal L40e family DUF2296 PF10058.4 AAS53397.1 - 0.45 10.2 3.0 1.1 9.0 0.1 2.1 1 1 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) Zn-ribbon_8 PF09723.5 AAS53397.1 - 0.52 10.3 3.1 2 8.4 2.1 1.9 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 AAS53397.1 - 0.83 9.2 4.3 2.7 7.6 3.0 2.0 1 1 0 1 1 1 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 AAS53397.1 - 0.99 9.2 4.2 3 7.7 0.4 2.0 1 1 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.1 AAS53397.1 - 1.1 8.9 4.7 4.2 7.1 3.3 2.0 1 1 0 1 1 1 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 AAS53397.1 - 1.2 9.4 5.0 4 7.7 0.8 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Siah-Interact_N PF09032.6 AAS53398.2 - 0.028 14.4 1.7 0.92 9.6 0.1 2.9 2 1 0 2 2 2 0 Siah interacting protein, N terminal Amidase02_C PF12123.3 AAS53398.2 - 0.14 11.8 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF607 PF04678.8 AAS53398.2 - 0.28 11.1 2.4 0.2 11.5 0.2 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF607 Paralemmin PF03285.10 AAS53398.2 - 0.44 9.9 6.4 0.3 10.5 2.9 1.7 1 1 0 1 1 1 0 Paralemmin Fimbrial_PilY2 PF14481.1 AAS53400.2 - 0.096 12.1 0.1 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 FAM196 PF15265.1 AAS53401.1 - 0.053 12.7 1.4 0.77 8.9 0.0 2.2 2 0 0 2 2 2 0 FAM196 family GTP_EFTU PF00009.22 AAS53402.2 - 1e-53 181.5 0.0 2.7e-53 180.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 AAS53402.2 - 1.2e-14 53.8 0.0 3.3e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AAS53402.2 - 1.3e-11 44.3 0.0 4.2e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 AAS53402.2 - 2.9e-08 33.4 0.0 6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 AAS53402.2 - 8.9e-05 22.0 0.0 0.00024 20.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 AAS53402.2 - 0.0076 16.1 0.0 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF952 PF06108.7 AAS53402.2 - 0.14 11.9 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF952) UPF1_Zn_bind PF09416.5 AAS53403.1 - 0.081 12.4 0.9 0.1 12.1 0.6 1.2 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) MNNL PF07657.8 AAS53403.1 - 0.21 11.5 1.7 0.26 11.2 1.2 1.2 1 0 0 1 1 1 0 N terminus of Notch ligand zf-TRAF PF02176.13 AAS53403.1 - 0.34 11.3 3.7 0.43 10.9 0.1 2.0 1 1 1 2 2 2 0 TRAF-type zinc finger Zn-ribbon_8 PF09723.5 AAS53403.1 - 0.98 9.4 4.2 0.44 10.5 0.8 1.9 2 1 0 2 2 2 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.11 AAS53403.1 - 1.1 9.0 6.2 17 5.2 4.3 2.4 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain IBR PF01485.16 AAS53403.1 - 1.1 9.1 5.8 0.69 9.8 0.5 2.1 1 1 1 2 2 2 0 IBR domain zf-tcix PF14952.1 AAS53403.1 - 1.4 8.3 4.8 1.7 8.0 0.0 2.4 2 1 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Chs3p PF12271.3 AAS53404.1 - 9.9e-85 284.0 18.1 1.7e-84 283.2 12.5 1.3 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit Ribosomal_L44 PF00935.14 AAS53405.1 - 1.4e-33 114.7 11.0 2.2e-33 114.1 7.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Pkinase PF00069.20 AAS53406.1 - 1.2e-59 201.5 0.4 7.4e-40 136.7 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53406.1 - 2.3e-26 92.4 0.4 3e-20 72.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AAS53406.1 - 0.0022 17.0 0.0 0.0066 15.4 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AAS53406.1 - 0.0039 16.2 0.0 0.012 14.6 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 AAS53406.1 - 0.0053 17.2 0.1 0.017 15.6 0.1 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 AAS53406.1 - 0.016 14.9 0.1 0.79 9.4 0.1 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AAS53406.1 - 0.032 13.0 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 AAS53406.1 - 0.073 11.8 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Far-17a_AIG1 PF04750.9 AAS53407.1 - 9.8e-16 57.5 3.5 1.1e-15 57.3 2.4 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Ammonium_transp PF00909.16 AAS53408.2 - 4.9e-111 371.0 26.8 6e-111 370.7 18.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Prefoldin_2 PF01920.15 AAS53410.2 - 2.3e-24 85.1 8.4 2.9e-24 84.8 5.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.10 AAS53410.2 - 0.2 11.1 10.7 1.7 8.1 0.7 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF4515 PF14988.1 AAS53410.2 - 0.28 10.8 9.9 2 8.0 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) FUSC PF04632.7 AAS53410.2 - 1.1 7.5 3.5 1.2 7.4 2.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4140 PF13600.1 AAS53410.2 - 5.8 7.4 12.6 1.1 9.6 3.6 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Pkinase PF00069.20 AAS53411.1 - 1.5e-31 109.4 0.9 3.7e-31 108.2 0.0 2.0 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53411.1 - 2.1e-11 43.3 0.0 2.1e-11 43.3 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 AAS53411.1 - 0.11 11.8 2.6 0.21 10.9 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL zf-AN1 PF01428.11 AAS53412.1 - 1.7e-11 43.8 8.8 2.9e-11 43.0 6.1 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger WLM PF08325.5 AAS53413.2 - 2.2e-50 171.1 0.0 2.9e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 AAS53413.2 - 0.013 15.3 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 INSIG PF07281.7 AAS53414.1 - 2e-09 37.0 2.2 2.6e-09 36.6 1.5 1.3 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) EBP PF05241.7 AAS53414.1 - 0.049 12.6 0.2 0.078 11.9 0.1 1.4 1 0 0 1 1 1 0 Emopamil binding protein MNHE PF01899.11 AAS53414.1 - 0.41 10.2 2.5 0.75 9.4 1.7 1.4 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit Endosulfine PF04667.12 AAS53415.1 - 3.5e-33 113.4 0.0 4.7e-33 113.0 0.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Peptidase_M14 PF00246.19 AAS53416.1 - 3.4e-72 243.3 0.0 4.1e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 AAS53416.1 - 0.051 12.4 0.0 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Pga1 PF10333.4 AAS53417.1 - 1.6e-75 252.7 0.0 1.8e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Qn_am_d_aII PF14930.1 AAS53417.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Arginase PF00491.16 AAS53419.2 - 1.3e-81 274.0 0.8 1.5e-81 273.7 0.6 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 AAS53419.2 - 0.055 13.6 0.6 0.091 12.9 0.4 1.3 1 0 0 1 1 1 0 UPF0489 domain Nucleoplasmin PF03066.10 AAS53420.1 - 1.6 8.2 5.5 2.6 7.5 3.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 AAS53420.1 - 6.1 6.4 6.5 10 5.6 4.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2009 PF09418.5 AAS53421.1 - 1.5e-229 762.4 0.1 1.8e-229 762.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 AAS53421.1 - 9.7e-05 22.1 5.1 0.00018 21.3 3.5 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-C3HC4_3 PF13920.1 AAS53421.1 - 0.22 11.2 6.5 0.41 10.3 4.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 AAS53421.1 - 0.37 10.7 6.7 0.087 12.7 2.1 1.8 2 0 0 2 2 2 0 IBR domain Actin PF00022.14 AAS53422.2 - 3.8e-124 414.0 0.0 4.4e-124 413.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AAS53422.2 - 0.027 13.0 0.0 2.3 6.7 0.0 2.7 2 1 0 2 2 2 0 MreB/Mbl protein UPRTase PF14681.1 AAS53423.1 - 4.9e-76 254.5 0.0 6.4e-76 254.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 AAS53423.1 - 0.0076 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 AAS53423.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) CoA_binding_2 PF13380.1 AAS53423.1 - 0.15 12.1 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain LSM PF01423.17 AAS53424.2 - 2.5e-18 65.3 0.1 3e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain CAP_GLY PF01302.20 AAS53425.2 - 8.4e-21 73.4 1.0 1.3e-20 72.7 0.2 1.8 2 0 0 2 2 2 1 CAP-Gly domain Ubiquitin_2 PF14560.1 AAS53425.2 - 0.042 14.1 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain PGA2 PF07543.7 AAS53426.1 - 4.8e-14 52.3 9.6 7.6e-08 32.2 2.5 2.0 1 1 1 2 2 2 2 Protein trafficking PGA2 DUF1049 PF06305.6 AAS53426.1 - 3.2 7.3 9.4 0.29 10.6 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) RNA_pol_3_Rpc31 PF11705.3 AAS53427.1 - 3.8e-68 229.8 11.6 4.3e-68 229.7 8.0 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF3295 PF11702.3 AAS53427.1 - 6 5.7 5.9 8 5.3 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) C2 PF00168.25 AAS53428.2 - 5.3e-09 35.7 0.0 9.8e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain Tho2 PF11262.3 AAS53429.2 - 2.4e-56 190.9 6.7 5.2e-56 189.8 2.8 2.7 2 1 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 AAS53429.2 - 6.9e-26 89.8 0.1 1.8e-25 88.5 0.0 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit SF3b10 PF07189.6 AAS53430.1 - 2.5e-26 91.3 0.0 2.8e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) CAP_N PF01213.14 AAS53432.2 - 5.4e-90 301.8 0.0 7e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 AAS53432.2 - 6.7e-62 207.5 0.2 8.7e-62 207.1 0.1 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 AAS53432.2 - 0.02 14.2 1.3 0.034 13.5 0.9 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C S4 PF01479.20 AAS53433.1 - 5.6e-14 51.3 0.0 1.1e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 AAS53433.1 - 0.0096 15.4 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 S4 domain Prp19 PF08606.6 AAS53433.1 - 0.029 14.1 0.1 0.12 12.0 0.1 2.1 1 0 0 1 1 1 0 Prp19/Pso4-like Pyrophosphatase PF00719.14 AAS53433.1 - 0.1 12.0 2.6 0.13 11.7 0.2 2.1 2 0 0 2 2 2 0 Inorganic pyrophosphatase LTXXQ PF07813.7 AAS53433.1 - 0.51 10.8 7.3 0.23 11.9 1.0 2.5 2 0 0 2 2 2 0 LTXXQ motif family protein Eaf7 PF07904.8 AAS53434.1 - 1.7e-29 101.6 0.0 2.5e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 zf-PARP PF00645.13 AAS53434.1 - 0.05 13.8 0.1 0.1 12.8 0.1 1.5 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF605 PF04652.11 AAS53434.1 - 4.3 6.6 13.3 5.9 6.1 9.2 1.1 1 0 0 1 1 1 0 Vta1 like FKBP_C PF00254.23 AAS53435.1 - 9.7e-33 112.0 0.0 1.1e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PIR PF00399.14 AAS53436.2 - 2.9e-06 26.4 4.0 9.1e-06 24.8 2.8 1.9 1 0 0 1 1 1 1 Yeast PIR protein repeat ADH_zinc_N PF00107.21 AAS53437.2 - 9.5e-10 38.1 0.0 1.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AAS53437.2 - 0.00026 20.7 0.0 0.0026 17.4 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cpn60_TCP1 PF00118.19 AAS53438.1 - 6.2e-148 493.4 3.7 7.1e-148 493.2 2.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Snf7 PF03357.16 AAS53439.1 - 1e-15 57.5 16.2 1.5e-15 57.0 11.2 1.2 1 0 0 1 1 1 1 Snf7 T2SM PF04612.7 AAS53439.1 - 0.033 13.9 9.0 0.053 13.3 0.2 2.3 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M Baculo_PEP_C PF04513.7 AAS53439.1 - 0.054 13.3 4.0 0.034 13.9 1.0 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 AAS53439.1 - 0.35 10.7 7.2 0.48 10.3 1.8 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DASH_Dad2 PF08654.5 AAS53439.1 - 0.89 9.5 9.7 0.064 13.2 1.1 2.8 1 1 2 3 3 3 0 DASH complex subunit Dad2 Spore_coat_CotO PF14153.1 AAS53439.1 - 3.7 6.9 9.2 2.2 7.6 1.1 2.1 2 0 0 2 2 2 0 Spore coat protein CotO APG6 PF04111.7 AAS53439.1 - 4.3 6.3 10.7 2.2 7.2 0.9 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Syntaxin_2 PF14523.1 AAS53439.1 - 6.1 6.9 9.8 4.1 7.4 2.8 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Dak2 PF02734.12 AAS53439.1 - 6.2 6.4 9.1 3 7.4 1.1 2.4 1 1 1 2 2 2 0 DAK2 domain GATA PF00320.22 AAS53440.2 - 1.4e-15 56.3 3.1 2.4e-15 55.5 2.1 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF2387 PF09526.5 AAS53440.2 - 0.00026 20.8 0.1 0.00052 19.8 0.1 1.4 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) TF_Zn_Ribbon PF08271.7 AAS53440.2 - 0.051 12.9 1.2 0.09 12.1 0.9 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding DOPA_dioxygen PF08883.6 AAS53441.1 - 5.5e-27 93.8 0.0 6.3e-27 93.6 0.0 1.0 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family PLDc PF00614.17 AAS53442.2 - 1.2e-15 56.6 0.9 2.6e-07 30.1 0.2 3.0 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 AAS53442.2 - 2.2e-12 46.8 0.1 1.9e-08 34.1 0.1 3.3 2 1 0 2 2 2 2 PLD-like domain PX PF00787.19 AAS53442.2 - 4.2e-05 23.3 4.1 0.033 13.9 0.2 3.8 3 0 0 3 3 3 2 PX domain UNC-50 PF05216.8 AAS53444.1 - 2.8e-88 295.0 17.7 3.1e-88 294.8 12.3 1.0 1 0 0 1 1 1 1 UNC-50 family BP28CT PF08146.7 AAS53445.1 - 4.9e-42 143.2 4.9 4.9e-42 143.2 3.4 3.4 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 AAS53445.1 - 1.9e-21 76.2 2.6 1.9e-21 76.2 1.8 5.5 6 1 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 DUF1957 PF09210.6 AAS53445.1 - 0.017 15.1 0.5 0.077 13.0 0.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) HEAT_EZ PF13513.1 AAS53445.1 - 0.048 14.1 4.8 2 9.0 0.1 5.0 5 0 0 5 5 5 0 HEAT-like repeat HEAT_2 PF13646.1 AAS53445.1 - 0.054 13.7 8.7 3.7 7.9 0.0 5.5 6 1 0 6 6 6 0 HEAT repeats HEAT PF02985.17 AAS53445.1 - 0.67 10.1 6.8 31 5.0 0.1 5.1 3 0 0 3 3 3 0 HEAT repeat DUF1212 PF06738.7 AAS53446.1 - 3.2e-49 167.0 17.3 9.5e-48 162.2 1.5 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 AAS53446.1 - 6.7e-27 93.9 12.1 6.7e-27 93.9 8.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) Herpes_UL37_1 PF03970.8 AAS53446.1 - 0.046 12.5 0.4 0.83 8.4 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus UL37 tegument protein Peptidase_A8 PF01252.13 AAS53446.1 - 0.23 11.0 5.9 0.043 13.4 0.6 2.1 2 0 0 2 2 2 0 Signal peptidase (SPase) II FA_desaturase PF00487.19 AAS53446.1 - 8.3 5.7 6.6 6.9 6.0 1.7 2.2 2 0 0 2 2 2 0 Fatty acid desaturase Pkinase PF00069.20 AAS53447.1 - 1.5e-53 181.6 0.1 1.6e-51 174.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53447.1 - 3.6e-27 95.0 0.1 2e-26 92.6 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Dicty_REP PF05086.7 AAS53447.1 - 0.0026 15.6 25.7 0.069 10.8 4.7 2.2 2 0 0 2 2 2 2 Dictyostelium (Slime Mold) REP protein VIT PF08487.5 AAS53447.1 - 0.0052 16.4 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Kdo PF06293.9 AAS53447.1 - 0.014 14.4 0.1 0.029 13.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mucin PF01456.12 AAS53447.1 - 0.025 14.3 43.6 0.24 11.1 5.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein PHD PF00628.24 AAS53448.2 - 2.7e-10 39.7 8.1 5.3e-10 38.8 5.6 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 AAS53448.2 - 2.3e-06 28.0 0.3 1.6e-05 25.2 0.0 2.5 3 1 0 3 3 3 1 SET domain PHD_2 PF13831.1 AAS53448.2 - 0.0014 17.8 3.7 0.0014 17.8 2.6 1.8 2 0 0 2 2 2 1 PHD-finger Sec3-PIP2_bind PF15277.1 AAS53448.2 - 0.0087 15.9 0.4 0.084 12.7 0.0 2.6 3 0 0 3 3 3 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH zf-CW PF07496.10 AAS53448.2 - 0.04 13.6 2.5 0.089 12.5 0.5 2.3 2 0 0 2 2 2 0 CW-type Zinc Finger Pam16 PF03656.8 AAS53449.2 - 3e-47 159.5 0.2 3.4e-47 159.3 0.2 1.0 1 0 0 1 1 1 1 Pam16 NTP_transferase PF00483.18 AAS53449.2 - 0.089 12.0 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyl transferase Closter_coat PF01785.12 AAS53449.2 - 0.1 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Closterovirus coat protein zf-CCCH PF00642.19 AAS53450.1 - 0.54 9.9 38.1 0.33 10.6 2.6 5.8 5 1 1 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2HC5 PF06221.8 AAS53451.1 - 2.3e-20 72.1 9.6 3.9e-20 71.3 6.6 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type 4F5 PF04419.9 AAS53451.1 - 0.93 10.2 12.3 1.4 9.6 0.5 3.8 3 0 0 3 3 3 0 4F5 protein family RNA_pol_Rpb1_1 PF04997.7 AAS53451.1 - 4.6 6.4 11.9 0.074 12.2 2.1 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 1 Zn_clus PF00172.13 AAS53452.1 - 2.2e-07 30.6 10.8 4.1e-07 29.7 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 AAS53452.1 - 0.00021 21.0 0.0 0.00045 19.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 AAS53452.1 - 0.052 13.4 0.0 0.71 9.8 0.0 2.5 2 0 0 2 2 2 0 PAS domain PAS_9 PF13426.1 AAS53452.1 - 0.1 12.9 0.1 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 PAS domain DEAD PF00270.24 AAS53453.1 - 7.3e-38 129.7 0.0 1e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS53453.1 - 4.2e-18 64.9 0.0 8.4e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 AAS53453.1 - 1e-17 63.4 0.0 2e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 AAS53453.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sin_N PF04801.8 AAS53454.1 - 5.3e-17 61.7 0.2 1.4e-16 60.3 0.2 1.6 1 1 0 1 1 1 1 Sin-like protein conserved region IF-2B PF01008.12 AAS53455.2 - 7.2e-71 238.4 0.0 8.7e-71 238.1 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family GTP_EFTU PF00009.22 AAS53456.1 - 9.5e-58 194.7 0.0 1.9e-57 193.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 AAS53456.1 - 1.3e-26 92.1 0.0 2.7e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 AAS53456.1 - 3.9e-18 65.0 0.0 7.8e-09 35.2 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AAS53456.1 - 1.2e-10 41.3 1.2 4e-10 39.6 0.2 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AAS53456.1 - 0.0027 17.6 0.0 0.0072 16.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GCS PF03074.11 AAS53457.1 - 3.1e-137 457.5 0.0 3.9e-137 457.2 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.8 AAS53457.1 - 0.0045 16.1 0.1 0.009 15.1 0.1 1.4 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) YqbF PF14553.1 AAS53457.1 - 0.075 12.7 1.1 0.14 11.8 0.1 2.0 2 0 0 2 2 2 0 YqbF, hypothetical protein domain PI3_PI4_kinase PF00454.22 AAS53458.2 - 5.7e-53 179.8 0.0 7.7e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ChAPs PF09295.5 AAS53459.1 - 3.6e-49 167.5 0.0 1.2e-39 136.2 0.0 2.2 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 AAS53459.1 - 2e-08 33.7 0.4 2.5e-05 23.8 0.1 3.5 3 1 0 3 3 3 1 TPR repeat TPR_19 PF14559.1 AAS53459.1 - 6.9e-05 23.1 1.5 0.00089 19.5 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 AAS53459.1 - 0.00013 21.6 3.3 0.25 11.3 0.1 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 AAS53459.1 - 0.0017 18.0 0.0 0.76 9.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 AAS53459.1 - 0.0019 18.3 0.3 0.031 14.4 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 AAS53459.1 - 0.0029 18.2 0.8 0.082 13.6 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 AAS53459.1 - 0.0032 17.0 1.3 0.18 11.4 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 AAS53459.1 - 0.0044 16.9 0.7 0.031 14.2 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 AAS53459.1 - 0.02 15.0 0.6 0.24 11.7 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 AAS53459.1 - 0.056 13.3 0.1 21 5.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 AAS53459.1 - 0.13 12.1 0.3 58 3.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AAS53459.1 - 0.28 11.9 3.2 1e+02 3.9 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SAPS PF04499.10 AAS53460.2 - 3.8e-176 586.4 0.0 3.8e-176 586.4 0.0 3.1 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein DUF903 PF06004.7 AAS53460.2 - 0.079 12.5 0.9 5.6 6.5 0.0 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF903) PTPLA PF04387.9 AAS53461.1 - 5.8e-49 165.6 9.7 9.7e-49 164.9 6.7 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Abhydrolase_9_N PF15420.1 AAS53461.1 - 7.8 6.1 11.0 3.7 7.2 0.4 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Ribosomal_L21p PF00829.16 AAS53462.1 - 0.00014 21.9 0.0 0.00018 21.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.20 AAS53463.1 - 1.9e-64 217.2 0.0 4.4e-64 216.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53463.1 - 4.3e-44 150.5 0.0 7.8e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS53463.1 - 2.1e-09 36.7 0.0 6.5e-07 28.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_2 PF07647.12 AAS53463.1 - 0.0095 15.7 0.2 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 AAS53463.1 - 0.039 13.7 0.7 0.11 12.2 0.5 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain APH PF01636.18 AAS53463.1 - 0.28 10.8 0.0 0.46 10.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family UvrD_C PF13361.1 AAS53464.2 - 1.9e-65 221.6 0.1 7.2e-38 130.9 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 AAS53464.2 - 5e-60 203.4 0.0 1.9e-59 201.5 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 AAS53464.2 - 8.3e-09 35.5 0.0 7e-05 22.9 0.0 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 AAS53464.2 - 2.1e-08 33.7 1.2 4.3e-08 32.7 0.0 2.2 3 0 0 3 3 3 1 Part of AAA domain AAA_12 PF13087.1 AAS53464.2 - 0.00086 18.7 0.0 0.02 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 AAS53464.2 - 0.0018 17.8 0.0 0.0064 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 AAS53464.2 - 0.0053 16.2 0.5 33 3.8 0.0 4.2 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase GWT1 PF06423.7 AAS53465.1 - 1.9e-47 160.7 4.8 5e-47 159.3 3.3 1.8 1 0 0 1 1 1 1 GWT1 BRCT PF00533.21 AAS53466.2 - 2.3e-11 43.6 0.0 0.001 19.1 0.0 3.6 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AAS53466.2 - 3.9e-10 39.4 0.2 0.00011 22.0 0.0 4.1 4 0 0 4 4 4 2 twin BRCT domain Zn_clus PF00172.13 AAS53467.2 - 5.7e-10 38.9 11.8 8.5e-10 38.3 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NTR2 PF15458.1 AAS53468.1 - 7.9e-33 113.7 6.7 1e-32 113.3 4.7 1.2 1 0 0 1 1 1 1 Nineteen complex-related protein 2 bZIP_Maf PF03131.12 AAS53468.1 - 0.016 15.4 1.1 0.48 10.7 0.0 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor OTCace PF00185.19 AAS53469.1 - 2e-43 147.9 1.0 3.6e-43 147.1 0.4 1.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 AAS53469.1 - 3.4e-43 146.6 0.4 2e-42 144.2 0.0 2.0 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain RNA_lig_T4_1 PF09511.5 AAS53470.2 - 3.2e-78 262.2 0.0 4.1e-77 258.6 0.0 2.4 2 1 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.6 AAS53470.2 - 5e-74 247.7 0.7 9.3e-74 246.8 0.5 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 AAS53470.2 - 1.3e-73 247.3 0.1 2.2e-73 246.6 0.0 1.4 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain CPT PF07931.7 AAS53470.2 - 0.032 13.8 0.0 0.083 12.5 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RVT_thumb PF06817.9 AAS53470.2 - 0.049 13.2 0.1 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase thumb domain PRK PF00485.13 AAS53470.2 - 0.057 12.9 0.5 0.22 11.0 0.0 2.2 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Exo70 PF03081.10 AAS53471.1 - 2.9e-92 309.3 2.6 2.9e-92 309.3 1.8 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Arrestin_C PF02752.17 AAS53472.2 - 1e-15 58.0 0.1 2.6e-14 53.4 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 AAS53472.2 - 1.5e-05 24.8 0.0 0.0053 16.5 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain DND1_DSRM PF14709.1 AAS53472.2 - 0.074 13.3 0.0 0.74 10.1 0.0 2.7 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Vps51 PF08700.6 AAS53473.1 - 4.1e-14 52.1 0.1 4.1e-14 52.1 0.1 2.0 2 0 0 2 2 2 1 Vps51/Vps67 EF-hand_4 PF12763.2 AAS53474.1 - 6.7e-05 22.5 0.1 6.7e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand AP2 PF00847.15 AAS53474.1 - 0.016 15.3 0.1 0.051 13.7 0.1 1.9 1 0 0 1 1 1 0 AP2 domain Sigma70_ner PF04546.8 AAS53474.1 - 3.7 7.1 9.6 6.9 6.2 4.0 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region IBR PF01485.16 AAS53475.1 - 5.5e-16 58.2 24.0 1.9e-09 37.2 3.0 3.9 3 1 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 AAS53475.1 - 1.2 8.8 48.7 0.021 14.4 9.4 4.7 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS53475.1 - 9.6 6.3 49.0 2.2 8.3 6.2 4.6 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Actin PF00022.14 AAS53476.1 - 1.2e-95 320.2 0.0 5.1e-95 318.2 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AAS53476.1 - 0.08 11.5 0.0 1.3 7.5 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Mitofilin PF09731.4 AAS53477.2 - 4.8e-115 385.4 20.6 3.7e-100 336.2 14.5 2.0 1 1 0 2 2 2 2 Mitochondrial inner membrane protein Baculo_PEP_C PF04513.7 AAS53477.2 - 9.2 6.0 11.4 8.1 6.2 0.5 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RRM_1 PF00076.17 AAS53478.1 - 5.2e-41 138.1 1.3 2.6e-19 68.5 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS53478.1 - 1.1e-29 102.2 0.0 1.4e-16 60.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS53478.1 - 3.4e-21 74.8 0.0 5.8e-12 45.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 AAS53478.1 - 0.053 11.9 34.8 0.065 11.7 24.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SLD3 PF08639.5 AAS53478.1 - 0.66 8.5 31.8 0.79 8.2 22.0 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 Arrestin_N PF00339.24 AAS53479.1 - 2.3e-20 72.9 0.0 3.1e-18 66.0 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 AAS53479.1 - 4.4e-09 36.5 0.1 1e-08 35.3 0.1 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain RNase_PH PF01138.16 AAS53480.1 - 3.2e-18 66.3 0.0 4.5e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PEMT PF04191.8 AAS53481.1 - 3.7e-51 171.6 15.5 3.8e-28 97.6 1.2 3.4 3 1 1 4 4 4 2 Phospholipid methyltransferase ICMT PF04140.9 AAS53481.1 - 0.029 14.5 6.0 1.3 9.2 0.3 3.7 2 1 1 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Septin PF00735.13 AAS53482.2 - 4.4e-115 383.5 0.4 4.4e-115 383.5 0.3 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 AAS53482.2 - 3.1e-06 27.1 0.2 1.3e-05 25.1 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 AAS53482.2 - 0.00054 19.8 0.1 0.0025 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AAS53482.2 - 0.00085 18.5 0.1 0.0025 16.9 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 AAS53482.2 - 0.00092 19.2 0.2 0.016 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Lipocalin PF00061.18 AAS53482.2 - 0.0081 16.1 0.5 0.027 14.4 0.3 1.9 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family AAA_10 PF12846.2 AAS53482.2 - 0.011 15.2 0.3 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain GTP_EFTU PF00009.22 AAS53482.2 - 0.015 14.7 4.4 0.041 13.3 0.0 2.9 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 AAS53482.2 - 0.02 15.1 2.6 0.53 10.5 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.1 AAS53482.2 - 0.028 14.5 1.1 0.11 12.6 0.0 2.5 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.1 AAS53482.2 - 0.04 13.8 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 AAS53482.2 - 0.044 13.2 0.0 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 AAS53482.2 - 0.057 13.2 11.6 0.15 11.9 0.0 3.4 2 2 1 3 3 3 0 Dynamin family AAA_24 PF13479.1 AAS53482.2 - 0.11 12.0 6.6 0.12 11.9 0.1 2.9 3 0 0 3 3 3 0 AAA domain DUF2937 PF11157.3 AAS53482.2 - 0.41 9.9 4.9 0.77 9.0 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF342 PF03961.8 AAS53482.2 - 0.92 7.8 13.5 1.7 6.9 9.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AIG1 PF04548.11 AAS53482.2 - 1.5 7.8 8.3 0.43 9.6 0.6 2.8 2 1 0 2 2 2 0 AIG1 family IncA PF04156.9 AAS53482.2 - 4.5 6.8 15.6 8.5 5.9 10.8 1.4 1 0 0 1 1 1 0 IncA protein Exonuc_VII_L PF02601.10 AAS53482.2 - 9.2 5.3 12.1 15 4.6 8.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SHNi-TPR PF10516.4 AAS53483.2 - 2.2e-16 58.8 5.1 5.5e-16 57.5 0.4 3.1 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 AAS53483.2 - 0.0031 17.1 6.8 0.016 14.8 0.9 3.1 2 1 2 4 4 4 2 TPR repeat TPR_12 PF13424.1 AAS53483.2 - 0.011 15.7 1.7 0.011 15.7 1.2 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat Pterin_4a PF01329.14 AAS53483.2 - 0.14 11.9 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase TPR_2 PF07719.12 AAS53483.2 - 2.3 8.3 16.5 1.8 8.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.1 AAS53483.2 - 2.4 7.2 9.8 9.6 5.2 6.8 1.9 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP MxiH PF09392.5 AAS53483.2 - 8.6 7.0 7.1 8.9e+02 0.5 4.9 3.2 1 1 0 1 1 1 0 Type III secretion needle MxiH like UPF0121 PF03661.8 AAS53484.1 - 1e-07 31.3 1.1 1.3e-07 31.0 0.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) HSP70 PF00012.15 AAS53485.1 - 6.7e-274 909.4 7.2 7.6e-274 909.2 5.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AAS53485.1 - 3.7e-18 65.2 0.0 7.1e-17 60.9 0.0 2.3 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 AAS53485.1 - 0.00034 19.7 0.8 0.011 14.8 0.0 2.8 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 AAS53485.1 - 0.00066 19.3 0.0 0.0016 18.0 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF1484 PF07363.6 AAS53485.1 - 0.1 12.9 0.4 18 5.7 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) GAF_2 PF13185.1 AAS53486.1 - 4.4e-07 30.4 0.0 5.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 AAS53486.1 - 0.00011 22.4 0.0 0.00018 21.6 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 AAS53486.1 - 0.0027 17.7 0.0 0.0046 17.0 0.0 1.3 1 1 0 1 1 1 1 GAF domain Methyltransf_28 PF02636.12 AAS53486.1 - 0.054 12.8 0.0 0.054 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ferric_reduct PF01794.14 AAS53487.1 - 1.2e-15 57.7 14.5 2.3e-15 56.7 8.7 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 AAS53487.1 - 1.4e-11 44.1 0.0 3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 AAS53487.1 - 4.2e-06 26.7 0.0 3.3e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 AAS53487.1 - 0.2 12.2 0.0 9.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4131 PF13567.1 AAS53487.1 - 1.9 7.8 8.2 1.3 8.3 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Fungal_trans PF04082.13 AAS53488.2 - 3.2e-09 36.0 1.8 7.6e-09 34.8 1.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS53488.2 - 5.1e-08 32.6 9.1 9.8e-08 31.7 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tropomyosin PF00261.15 AAS53489.1 - 0.0096 15.0 7.0 0.0096 15.0 4.8 1.3 1 1 0 1 1 1 1 Tropomyosin DUF2937 PF11157.3 AAS53489.1 - 0.048 12.9 3.9 0.074 12.3 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) SDP_N PF12278.3 AAS53489.1 - 0.056 13.0 0.3 0.078 12.6 0.2 1.2 1 0 0 1 1 1 0 Sex determination protein N terminal RHH_3 PF12651.2 AAS53489.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix domain NTase_sub_bind PF08780.6 AAS53489.1 - 0.1 12.3 1.9 0.15 11.8 1.3 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like Endotoxin_N PF03945.9 AAS53489.1 - 0.14 11.5 1.3 0.19 11.1 0.9 1.1 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain YlqD PF11068.3 AAS53489.1 - 0.7 9.9 12.4 0.7 9.9 7.8 1.5 1 1 0 1 1 1 0 YlqD protein Macoilin PF09726.4 AAS53489.1 - 0.71 8.0 4.6 0.88 7.7 3.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Baculo_PEP_C PF04513.7 AAS53489.1 - 0.75 9.6 7.2 0.24 11.2 3.1 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 AAS53489.1 - 0.96 9.1 5.0 1.7 8.3 3.4 1.3 1 0 0 1 1 1 0 Laminin Domain II DivIVA PF05103.8 AAS53489.1 - 1.1 9.2 8.3 0.23 11.5 3.1 1.9 2 1 0 2 2 2 0 DivIVA protein DUF904 PF06005.7 AAS53489.1 - 1.3 9.3 15.1 4.1 7.7 3.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF724 PF05266.9 AAS53489.1 - 1.4 8.5 8.0 2.2 7.8 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) IncA PF04156.9 AAS53489.1 - 4.5 6.8 15.4 13 5.3 10.7 1.7 1 1 0 1 1 1 0 IncA protein TBPIP PF07106.8 AAS53489.1 - 4.8 6.7 10.5 4.6 6.7 5.8 1.7 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ABC1 PF03109.11 AAS53490.2 - 3.7e-31 107.5 0.1 1e-30 106.1 0.0 1.8 2 0 0 2 2 2 1 ABC1 family RIO1 PF01163.17 AAS53490.2 - 0.0038 16.6 0.0 0.025 13.9 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Mpv17_PMP22 PF04117.7 AAS53491.1 - 3e-28 97.2 3.5 3e-28 97.2 2.4 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family TP_methylase PF00590.15 AAS53494.1 - 5e-23 81.8 0.0 7.4e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.1 AAS53494.1 - 0.091 12.4 0.0 0.35 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) Clat_adaptor_s PF01217.15 AAS53495.1 - 2.7e-54 182.7 1.4 3.1e-54 182.5 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HlyC PF02794.11 AAS53496.1 - 0.054 13.1 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 RTX toxin acyltransferase family Mem_trans PF03547.13 AAS53497.1 - 5.7e-56 189.4 9.8 7.5e-56 189.0 6.8 1.1 1 0 0 1 1 1 1 Membrane transport protein Erv26 PF04148.8 AAS53498.2 - 1.4e-82 276.1 5.0 1.7e-82 275.9 3.5 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 7TM_GPCR_Srh PF10318.4 AAS53498.2 - 0.00085 18.2 5.8 0.00085 18.2 4.0 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srh 6PGD PF00393.14 AAS53500.2 - 9.1e-132 438.6 0.0 1.1e-131 438.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 AAS53500.2 - 1.1e-52 178.2 0.0 1.5e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AAS53500.2 - 0.0032 17.8 0.1 0.0058 17.0 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 AAS53500.2 - 0.015 14.4 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.1 AAS53500.2 - 0.029 14.4 0.1 0.12 12.3 0.0 2.1 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.13 AAS53500.2 - 0.15 11.6 0.1 0.44 10.1 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mito_carr PF00153.22 AAS53502.2 - 2.2e-61 203.5 0.0 2.3e-23 81.7 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein PsaL PF02605.10 AAS53502.2 - 0.091 12.2 0.4 0.24 10.9 0.3 1.7 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI XPG_N PF00752.12 AAS53504.1 - 3.3e-35 120.3 0.0 7.8e-35 119.1 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 AAS53504.1 - 2e-24 85.4 0.0 5.2e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 AAS53504.1 - 0.00052 20.1 0.0 0.0016 18.6 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.2 AAS53504.1 - 0.019 14.4 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 XPG domain containing Ligase_CoA PF00549.14 AAS53505.2 - 3.2e-24 85.2 1.1 5.4e-24 84.5 0.8 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 AAS53505.2 - 1e-22 80.4 3.8 5.1e-22 78.1 1.0 2.2 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 AAS53505.2 - 1.6e-09 37.4 0.2 2.6e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 AAS53505.2 - 8.5e-06 25.9 0.4 4.5e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 CoA binding domain Actin PF00022.14 AAS53506.1 - 2.6e-22 78.8 0.0 1.9e-16 59.4 0.0 3.4 3 1 0 3 3 3 3 Actin MreB_Mbl PF06723.8 AAS53506.1 - 4.7e-06 25.4 0.0 7.9e-05 21.3 0.0 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 AAS53506.1 - 0.066 13.0 0.1 0.27 11.0 0.1 2.0 2 0 0 2 2 2 0 Cell division protein FtsA HSF_DNA-bind PF00447.12 AAS53507.1 - 7.8e-37 125.5 3.2 1.6e-36 124.6 2.2 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Iso_dh PF00180.15 AAS53508.1 - 3.5e-100 335.3 0.0 4e-100 335.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4591 PF15261.1 AAS53508.1 - 0.086 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) ThiF PF00899.16 AAS53509.1 - 1.9e-32 111.9 0.1 4.2e-32 110.8 0.1 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 AAS53509.1 - 1.9e-25 88.1 1.0 3.6e-25 87.3 0.7 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 AAS53509.1 - 1.8e-20 72.0 1.9 3.1e-20 71.2 1.3 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 AAS53509.1 - 1.5e-05 24.9 0.2 3.4e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 AAS53509.1 - 0.00019 21.6 0.3 0.0006 20.0 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 AAS53509.1 - 0.00039 20.5 0.0 0.00097 19.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 AAS53509.1 - 0.083 13.3 0.5 0.32 11.4 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RhoGAP PF00620.22 AAS53510.2 - 1.5e-30 105.7 0.2 7.6e-30 103.5 0.1 2.1 1 1 0 1 1 1 1 RhoGAP domain BAR PF03114.13 AAS53511.2 - 4.6e-57 193.1 1.9 5.6e-57 192.8 1.3 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 AAS53511.2 - 3.6e-16 58.2 0.0 5.9e-16 57.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AAS53511.2 - 1.2e-13 50.4 0.0 2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AAS53511.2 - 1.2e-07 31.0 0.0 2.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FAM92 PF06730.6 AAS53511.2 - 0.025 13.9 0.3 0.041 13.2 0.2 1.3 1 0 0 1 1 1 0 FAM92 protein ERCC4 PF02732.10 AAS53512.1 - 5.4e-25 87.8 0.0 1.1e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 AAS53512.1 - 0.00018 21.6 0.0 0.00043 20.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain GTP_EFTU PF00009.22 AAS53513.1 - 1.8e-63 213.3 0.1 2.6e-63 212.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 AAS53513.1 - 6.4e-37 125.7 0.0 1.9e-36 124.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 AAS53513.1 - 6e-21 74.1 0.0 1.5e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 AAS53513.1 - 1.3e-13 50.5 0.0 4.1e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 AAS53513.1 - 7.8e-12 45.1 1.6 1.9e-11 43.9 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AAS53513.1 - 5.5e-06 26.3 0.2 1.2e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 AAS53513.1 - 0.099 12.1 0.4 0.48 9.8 0.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SUKH-4 PF14435.1 AAS53513.1 - 0.14 11.8 0.1 0.65 9.6 0.0 2.1 3 0 0 3 3 3 0 SUKH-4 immunity protein PX PF00787.19 AAS53514.2 - 9.2e-11 41.5 0.0 2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 AAS53514.2 - 2.4e-08 33.5 7.3 3.7e-08 32.9 5.1 1.2 1 0 0 1 1 1 1 Vps5 C terminal like Grp1_Fun34_YaaH PF01184.14 AAS53515.1 - 3.2e-63 212.8 15.3 4.2e-63 212.4 10.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ribosomal_60s PF00428.14 AAS53516.1 - 1.7e-26 92.4 15.1 2e-26 92.2 10.5 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Mito_carr PF00153.22 AAS53517.1 - 9.6e-59 195.1 3.6 3e-19 68.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 AAS53518.2 - 1.4e-46 156.0 4.8 3.4e-16 58.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 AAS53520.1 - 4.5e-12 45.4 0.0 8e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS53520.1 - 1.1e-10 41.3 0.0 1.8e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS53520.1 - 0.00028 20.6 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 AAS53520.1 - 0.0032 17.8 1.1 0.0032 17.8 0.8 2.9 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Pkinase PF00069.20 AAS53521.1 - 3.6e-37 127.9 0.0 6.1e-37 127.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53521.1 - 1.7e-26 92.8 0.0 2.4e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AAS53521.1 - 9.6e-08 32.0 2.1 1.5e-05 24.9 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 AAS53521.1 - 4.9e-05 22.4 0.0 7.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AAS53521.1 - 0.00011 21.2 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 AAS53521.1 - 0.0073 15.8 0.0 0.44 10.0 0.0 2.2 1 1 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 AAS53521.1 - 0.011 15.0 0.0 0.028 13.7 0.0 1.7 2 0 0 2 2 2 0 RIO1 family FA_hydroxylase PF04116.8 AAS53522.2 - 3.9e-12 46.5 19.5 3.9e-12 46.5 13.5 2.7 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily ABC_tran PF00005.22 AAS53523.1 - 4.9e-18 65.7 0.0 2e-17 63.7 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AAS53523.1 - 4.6e-10 39.9 0.6 0.00035 20.6 0.1 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 AAS53523.1 - 6.5e-05 22.2 0.0 0.028 13.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 AAS53523.1 - 0.00031 19.9 0.0 0.00049 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 AAS53523.1 - 0.00041 19.5 0.0 0.29 10.1 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AAS53523.1 - 0.0013 18.1 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 AAS53523.1 - 0.0046 16.0 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_10 PF12846.2 AAS53523.1 - 0.0069 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 AAS53523.1 - 0.039 14.0 1.6 0.22 11.6 1.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AAS53523.1 - 0.04 14.7 0.9 0.091 13.5 0.6 1.9 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 AAS53523.1 - 0.061 13.1 0.1 0.097 12.4 0.1 1.3 1 0 0 1 1 1 0 Dynamin family AAA_23 PF13476.1 AAS53523.1 - 0.072 13.4 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 AAS53523.1 - 0.08 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 AAS53523.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 AAS53523.1 - 0.12 11.0 0.1 0.17 10.5 0.1 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 AAS53523.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 AAS53523.1 - 0.15 12.4 0.2 0.32 11.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain DUF3584 PF12128.3 AAS53523.1 - 0.17 9.2 0.1 0.23 8.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) WD40 PF00400.27 AAS53524.2 - 1.1e-12 47.3 7.7 0.0014 18.4 0.0 7.3 8 0 0 8 8 8 4 WD domain, G-beta repeat COPI_C PF06957.6 AAS53524.2 - 0.13 10.8 8.1 0.22 10.0 5.6 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Ycf1 PF05758.7 AAS53524.2 - 4 5.0 5.0 5.2 4.6 3.4 1.2 1 0 0 1 1 1 0 Ycf1 RabGAP-TBC PF00566.13 AAS53525.1 - 2.7e-17 62.9 1.6 4.8e-17 62.1 1.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CCDC142 PF14923.1 AAS53525.1 - 0.0013 17.1 0.6 0.0021 16.4 0.4 1.4 1 0 0 1 1 1 1 Coiled-coil protein 142 Cpn60_TCP1 PF00118.19 AAS53526.2 - 8.2e-116 387.4 8.7 9.3e-116 387.2 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AA_permease PF00324.16 AAS53527.2 - 2.4e-118 395.4 34.5 3e-118 395.1 23.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS53527.2 - 6.3e-32 110.6 36.0 8.3e-32 110.2 25.0 1.1 1 0 0 1 1 1 1 Amino acid permease HIT PF01230.18 AAS53528.1 - 8e-25 87.2 0.0 1.2e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AAS53528.1 - 9.9e-10 38.6 0.1 2e-09 37.7 0.1 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 AAS53528.1 - 0.046 13.3 0.9 0.1 12.2 0.6 1.7 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 AAA PF00004.24 AAS53529.2 - 1.4e-98 326.1 0.0 2.4e-48 163.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AAS53529.2 - 6.9e-18 64.3 1.3 1.9e-17 62.9 0.2 2.3 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 AAS53529.2 - 1.8e-13 50.7 0.0 4.9e-07 29.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 AAS53529.2 - 2e-13 49.9 0.0 1.5e-05 24.1 0.0 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 AAS53529.2 - 1.3e-12 47.6 1.5 3e-06 27.0 0.0 3.9 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AAS53529.2 - 1.6e-11 44.5 0.0 0.0011 19.0 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 AAS53529.2 - 1.9e-11 44.0 0.0 7.9e-06 25.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 AAS53529.2 - 2.5e-11 44.4 0.2 0.0011 19.7 0.0 4.0 5 0 0 5 5 2 2 AAA domain AAA_22 PF13401.1 AAS53529.2 - 5.5e-11 42.7 0.9 0.0012 18.9 0.1 4.1 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.8 AAS53529.2 - 2.4e-09 36.4 0.1 0.0014 17.4 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus CDC48_2 PF02933.12 AAS53529.2 - 3e-09 36.3 0.1 2.2e-08 33.6 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 AAS53529.2 - 8.8e-09 35.3 0.0 0.0029 17.5 0.0 3.4 4 0 0 4 4 4 2 AAA domain IstB_IS21 PF01695.12 AAS53529.2 - 5.7e-08 32.3 0.0 0.0067 15.8 0.0 3.0 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 AAS53529.2 - 8.8e-08 31.7 5.8 0.0027 17.1 0.2 4.2 2 2 1 3 3 3 2 AAA domain AAA_19 PF13245.1 AAS53529.2 - 2.2e-07 30.5 1.0 0.024 14.3 0.0 3.2 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 AAS53529.2 - 2.2e-07 30.9 0.0 0.0099 16.0 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.16 AAS53529.2 - 3.3e-07 29.6 0.4 0.027 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 AAS53529.2 - 5.8e-07 28.8 0.2 0.0078 15.3 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin KaiC PF06745.8 AAS53529.2 - 4.8e-06 25.8 3.0 0.29 10.1 0.0 3.7 2 2 2 4 4 4 2 KaiC ResIII PF04851.10 AAS53529.2 - 5.1e-06 26.4 0.1 0.0068 16.2 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 AAS53529.2 - 5.5e-06 26.1 1.6 0.11 12.0 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.1 AAS53529.2 - 1e-05 25.5 0.6 0.25 11.3 0.0 3.1 3 1 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 AAS53529.2 - 1.1e-05 25.0 0.1 0.11 11.9 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain PhoH PF02562.11 AAS53529.2 - 1.3e-05 24.5 0.2 0.098 11.8 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_18 PF13238.1 AAS53529.2 - 1.3e-05 25.4 0.0 0.19 12.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 AAS53529.2 - 1.7e-05 25.1 0.0 0.022 15.0 0.0 3.4 2 1 0 2 2 2 1 ABC transporter Vps4_C PF09336.5 AAS53529.2 - 2.2e-05 24.2 0.4 0.00028 20.6 0.1 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.12 AAS53529.2 - 3.2e-05 22.9 0.1 0.11 11.3 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 AAS53529.2 - 4.3e-05 23.5 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 AAS53529.2 - 9.6e-05 21.4 0.0 0.17 10.7 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 AAS53529.2 - 0.00011 22.0 0.1 0.39 10.3 0.1 3.7 2 2 1 3 3 3 1 Archaeal ATPase AAA_3 PF07726.6 AAS53529.2 - 0.00013 21.5 0.0 0.67 9.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 AAS53529.2 - 0.00014 21.6 0.0 0.16 11.6 0.0 2.7 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_11 PF13086.1 AAS53529.2 - 0.00024 20.7 0.0 0.67 9.4 0.0 2.5 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 AAS53529.2 - 0.00028 20.5 0.2 1.6 8.3 0.0 3.4 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 AAS53529.2 - 0.0005 19.1 0.0 0.69 8.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 AAS53529.2 - 0.001 18.6 0.1 1.7 8.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 AAS53529.2 - 0.0037 16.1 0.2 1.8 7.3 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain IPT PF01745.11 AAS53529.2 - 0.015 14.5 0.1 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 AAS53529.2 - 0.015 14.2 0.2 1.7 7.5 0.0 2.8 2 2 1 3 3 3 0 KAP family P-loop domain NTPase_1 PF03266.10 AAS53529.2 - 0.018 14.7 1.3 3.3 7.3 0.0 3.7 4 0 0 4 4 3 0 NTPase Zot PF05707.7 AAS53529.2 - 0.026 14.0 0.3 5.2 6.4 0.1 3.5 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) UPF0079 PF02367.12 AAS53529.2 - 0.038 13.6 0.1 6 6.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 AAS53529.2 - 0.046 13.5 0.0 4.7 7.0 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase T2SE PF00437.15 AAS53529.2 - 0.068 12.0 0.0 3.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DEAD PF00270.24 AAS53529.2 - 0.09 12.2 0.3 23 4.4 0.0 3.4 3 1 0 4 4 3 0 DEAD/DEAH box helicase KTI12 PF08433.5 AAS53529.2 - 0.13 11.4 0.2 13 4.9 0.0 2.7 2 1 0 2 2 2 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.13 AAS53529.2 - 0.18 11.3 0.0 16 4.9 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Cyclin_N PF00134.18 AAS53530.1 - 2.1e-17 62.8 0.0 3.2e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 AAS53530.1 - 2.1e-11 44.4 0.1 3.5e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin IL22 PF14565.1 AAS53530.1 - 0.056 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Na_Ca_ex PF01699.19 AAS53531.2 - 1.2e-52 177.2 32.4 2.2e-26 92.1 10.7 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MHC2-interact PF09307.5 AAS53532.1 - 0.0093 15.7 0.3 0.018 14.7 0.2 1.4 1 0 0 1 1 1 1 CLIP, MHC2 interacting Ribosomal_60s PF00428.14 AAS53534.1 - 3.9e-23 81.6 15.3 4.6e-23 81.4 10.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PNTB PF02233.11 AAS53534.1 - 0.036 12.8 2.2 0.043 12.6 1.5 1.0 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit MTTB PF06253.6 AAS53534.1 - 0.13 9.9 0.0 0.13 9.9 0.0 2.0 1 1 1 2 2 2 0 Trimethylamine methyltransferase (MTTB) tRNA_bind PF01588.15 AAS53535.1 - 2.5e-20 72.0 0.0 3.9e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain EMP24_GP25L PF01105.19 AAS53536.1 - 9.4e-42 142.7 0.0 1.2e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD LAP1C PF05609.7 AAS53536.1 - 0.095 11.3 0.1 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Metallophos PF00149.23 AAS53537.2 - 3.7e-44 150.5 0.1 4.5e-44 150.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Yip1 PF04893.12 AAS53538.1 - 0.022 14.2 16.7 0.038 13.5 11.6 1.6 1 1 0 1 1 1 0 Yip1 domain Kelch_6 PF13964.1 AAS53539.2 - 1.7e-14 53.2 0.4 6.9e-07 29.1 0.0 4.7 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 AAS53539.2 - 6.4e-12 44.8 2.0 3e-06 26.6 0.0 3.8 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 AAS53539.2 - 1e-06 28.2 1.8 0.0036 17.0 0.0 3.9 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 AAS53539.2 - 1.2e-06 28.1 1.6 0.001 18.7 0.0 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 AAS53539.2 - 1.5e-05 24.8 0.0 0.00036 20.4 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 AAS53539.2 - 1.7e-05 24.8 0.1 0.12 12.5 0.0 3.9 3 0 0 3 3 3 2 Galactose oxidase, central domain DUF3554 PF12074.3 AAS53540.2 - 6.2e-61 206.7 4.5 6.2e-61 206.7 3.1 5.6 3 3 2 5 5 5 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 AAS53540.2 - 3.5e-37 126.5 29.9 7.3e-11 42.1 0.0 13.5 8 4 6 14 14 14 10 HEAT repeats HEAT PF02985.17 AAS53540.2 - 1.5e-31 105.6 17.2 0.0029 17.5 0.0 18.8 21 0 0 21 21 21 7 HEAT repeat HEAT_EZ PF13513.1 AAS53540.2 - 2.5e-27 94.6 33.7 0.0014 19.0 1.4 18.2 13 7 7 20 20 20 7 HEAT-like repeat CLASP_N PF12348.3 AAS53540.2 - 5.3e-15 55.4 0.0 8.9e-05 21.9 0.0 6.7 5 1 3 8 8 8 4 CLASP N terminal Cnd1 PF12717.2 AAS53540.2 - 1.3e-11 44.6 6.6 0.072 12.9 0.3 9.4 7 2 1 9 9 9 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 AAS53540.2 - 1.7e-11 44.3 2.4 0.062 13.6 0.0 10.0 10 2 2 12 12 12 2 Vacuolar 14 Fab1-binding region DUF937 PF06078.6 AAS53540.2 - 0.089 13.0 0.8 84 3.3 0.0 4.8 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF937) Arm PF00514.18 AAS53540.2 - 1.9 8.4 7.2 9.7 6.1 0.1 5.9 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat DUF3392 PF11872.3 AAS53541.1 - 0.036 14.0 0.1 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3392) A_thal_3526 PF09713.5 AAS53541.1 - 0.11 12.6 0.1 0.12 12.4 0.0 1.3 1 1 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) rve_2 PF13333.1 AAS53541.1 - 0.43 10.6 2.0 0.55 10.3 0.0 2.0 1 1 1 2 2 2 0 Integrase core domain Zn_clus PF00172.13 AAS53542.1 - 2.9e-08 33.5 10.6 5.9e-08 32.4 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AAS53542.1 - 2.7e-07 29.5 0.2 4.1e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hist_deacetyl PF00850.14 AAS53543.1 - 7.6e-83 278.3 0.0 9.5e-83 278.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain MT-A70 PF05063.9 AAS53544.1 - 5.9e-53 179.0 0.1 8.9e-53 178.4 0.1 1.3 1 0 0 1 1 1 1 MT-A70 DUF1926 PF09095.6 AAS53544.1 - 0.055 12.7 0.1 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1926) Complex1_LYR PF05347.10 AAS53545.1 - 0.025 14.3 0.4 0.11 12.2 0.2 2.1 1 0 0 1 1 1 0 Complex 1 protein (LYR family) FGase PF05013.7 AAS53545.1 - 0.96 9.2 5.7 0.21 11.4 0.1 2.5 2 1 0 2 2 2 0 N-formylglutamate amidohydrolase RPAP2_Rtr1 PF04181.8 AAS53546.1 - 1.3e-18 66.8 0.5 1.9e-18 66.3 0.3 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family FERM_M PF00373.13 AAS53546.1 - 0.044 13.9 0.1 0.097 12.8 0.1 1.6 1 0 0 1 1 1 0 FERM central domain DUF747 PF05346.6 AAS53547.2 - 8.7e-98 327.4 14.5 1.2e-97 326.9 10.1 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family zf-UBR PF02207.15 AAS53548.1 - 1.5e-15 56.6 13.0 1.5e-15 56.6 9.0 2.6 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.18 AAS53549.1 - 4.9e-141 469.3 0.1 7e-141 468.8 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 AAS53549.1 - 5.7e-30 104.3 32.0 5.7e-30 104.3 22.2 3.0 5 0 0 5 5 5 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 AAS53549.1 - 7.3e-15 55.5 0.1 1.7e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 AAS53549.1 - 2.9e-09 36.3 0.0 3.1e-07 29.7 0.0 2.6 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AAS53549.1 - 1.4e-07 31.3 0.0 3.9e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AAS53549.1 - 0.00051 19.6 0.0 0.0034 16.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AAS53549.1 - 0.0012 18.3 0.1 0.0081 15.6 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 AAS53549.1 - 0.014 15.6 0.0 0.044 13.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Nol1_Nop2_Fmu PF01189.12 AAS53550.2 - 1.6e-83 280.3 0.0 2.3e-67 227.3 0.0 2.2 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 AAS53550.2 - 0.00098 19.1 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 AAS53550.2 - 0.036 14.6 0.2 0.2 12.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain UAF_Rrn10 PF05234.6 AAS53551.1 - 7.2e-30 103.4 0.0 9e-30 103.1 0.0 1.0 1 0 0 1 1 1 1 UAF complex subunit Rrn10 DUF1193 PF06702.7 AAS53551.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1193) Thiolase_C PF02803.13 AAS53552.1 - 0.091 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Thiolase, C-terminal domain LSM PF01423.17 AAS53553.1 - 8e-16 57.3 0.2 1.1e-15 56.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AAS53553.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain GDI PF00996.13 AAS53554.1 - 7e-215 713.3 0.1 8e-215 713.1 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 AAS53554.1 - 0.067 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ChaC PF04752.7 AAS53555.1 - 1.8e-50 171.3 0.0 2.1e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein DUF3647 PF12363.3 AAS53556.2 - 0.13 12.4 0.1 9.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Phage protein SbcCD_C PF13558.1 AAS53556.2 - 0.47 10.4 3.7 0.5 10.3 0.4 2.3 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit KH_1 PF00013.24 AAS53557.1 - 3.9e-14 52.0 0.0 4.7e-07 29.3 0.0 4.9 5 0 0 5 5 5 3 KH domain KH_3 PF13014.1 AAS53557.1 - 8.1e-11 41.3 1.5 3.5e-05 23.3 0.0 5.1 5 0 0 5 5 5 2 KH domain Phlebovirus_G2 PF07245.6 AAS53557.1 - 0.024 12.9 0.0 0.035 12.3 0.0 1.2 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Ribosomal_L19 PF01245.15 AAS53557.1 - 0.052 13.3 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L19 AAA PF00004.24 AAS53559.2 - 5.9e-94 311.2 0.0 2.1e-47 160.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AAS53559.2 - 2.1e-15 56.4 0.0 2.1e-08 33.5 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 AAS53559.2 - 1.7e-12 48.2 0.0 5e-07 30.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 AAS53559.2 - 1.7e-11 44.4 2.5 0.00023 21.1 0.0 3.6 3 2 0 3 3 2 2 AAA ATPase domain AAA_2 PF07724.9 AAS53559.2 - 5e-11 42.7 0.0 0.00038 20.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AAS53559.2 - 9.1e-11 42.0 0.1 0.011 15.9 0.0 4.8 3 2 1 4 4 3 2 AAA domain Zeta_toxin PF06414.7 AAS53559.2 - 1.4e-10 40.5 0.0 0.00058 19.0 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 AAS53559.2 - 4.5e-10 39.5 0.0 0.0014 18.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AAS53559.2 - 5.4e-10 39.2 0.0 0.00024 20.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 AAS53559.2 - 1.1e-09 38.1 0.1 0.0024 17.6 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 AAS53559.2 - 5.4e-09 36.4 0.0 0.00014 22.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.8 AAS53559.2 - 8.3e-09 34.6 0.0 0.00024 19.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus ABC_tran PF00005.22 AAS53559.2 - 1.1e-07 32.2 0.0 0.012 15.9 0.0 3.3 3 0 0 3 3 3 2 ABC transporter Vps4_C PF09336.5 AAS53559.2 - 1.1e-07 31.6 0.1 0.00025 20.8 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.17 AAS53559.2 - 1.1e-07 31.9 0.0 0.0099 16.0 0.0 3.0 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 AAS53559.2 - 4.9e-07 29.3 0.2 0.022 14.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 AAS53559.2 - 7.7e-07 29.2 0.1 0.024 14.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 AAS53559.2 - 1.3e-06 28.0 0.4 0.075 12.8 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 AAS53559.2 - 3.2e-06 26.6 2.8 1.9 7.8 0.0 4.5 2 2 2 4 4 4 2 AAA domain Mg_chelatase PF01078.16 AAS53559.2 - 3.2e-06 26.4 0.3 0.043 12.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AAS53559.2 - 1e-05 25.1 0.0 0.057 13.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 AAS53559.2 - 1.5e-05 24.9 0.0 0.079 12.8 0.0 3.0 2 0 0 2 2 2 2 Shikimate kinase Cytidylate_kin2 PF13189.1 AAS53559.2 - 1.9e-05 24.6 0.0 0.0017 18.3 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family NACHT PF05729.7 AAS53559.2 - 2.6e-05 23.9 0.1 0.65 9.6 0.0 3.5 4 0 0 4 4 3 2 NACHT domain Rad17 PF03215.10 AAS53559.2 - 9e-05 21.3 0.0 0.029 13.0 0.0 2.4 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 AAS53559.2 - 0.00025 20.8 0.0 2.7 7.6 0.0 3.7 3 2 1 4 4 3 1 Archaeal ATPase Viral_helicase1 PF01443.13 AAS53559.2 - 0.00029 20.4 0.0 0.88 9.0 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.1 AAS53559.2 - 0.00033 20.7 0.0 0.66 10.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.8 AAS53559.2 - 0.00042 19.3 0.0 0.13 11.1 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 AAS53559.2 - 0.00044 19.7 0.0 0.23 10.8 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.17 AAS53559.2 - 0.00066 18.6 0.0 0.32 9.8 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain CPT PF07931.7 AAS53559.2 - 0.00074 19.1 0.0 0.018 14.7 0.0 2.4 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 AAS53559.2 - 0.0013 17.8 0.0 1.4 7.9 0.0 3.2 2 1 1 3 3 3 1 KaiC Parvo_NS1 PF01057.12 AAS53559.2 - 0.0021 17.0 0.1 1.6 7.5 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 AAS53559.2 - 0.0027 17.3 0.0 2.3 7.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 AAS53559.2 - 0.0044 16.5 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SRPRB PF09439.5 AAS53559.2 - 0.0057 15.9 0.0 1.7 7.8 0.0 2.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_11 PF13086.1 AAS53559.2 - 0.0063 16.1 1.4 1.3 8.5 0.0 3.0 3 1 0 3 3 2 1 AAA domain PhoH PF02562.11 AAS53559.2 - 0.007 15.6 0.0 1.6 7.9 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein NTPase_1 PF03266.10 AAS53559.2 - 0.011 15.4 0.0 4.1 7.0 0.0 2.9 3 0 0 3 3 2 0 NTPase PduV-EutP PF10662.4 AAS53559.2 - 0.015 14.8 0.0 5.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 AAS53559.2 - 0.016 14.8 0.0 7.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 AAS53559.2 - 0.033 14.1 0.0 3.3 7.7 0.0 3.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase ResIII PF04851.10 AAS53559.2 - 0.048 13.4 0.0 5.3 6.8 0.0 2.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AFG1_ATPase PF03969.11 AAS53559.2 - 0.051 12.3 0.0 9.6 4.8 0.0 2.7 4 0 0 4 4 2 0 AFG1-like ATPase FeoB_N PF02421.13 AAS53559.2 - 0.055 12.7 0.1 2 7.6 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_31 PF13614.1 AAS53559.2 - 0.058 13.3 0.0 2.2 8.1 0.0 3.2 3 0 0 3 3 2 0 AAA domain DUF258 PF03193.11 AAS53559.2 - 0.074 12.2 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 AAS53559.2 - 0.15 11.5 0.0 8.4 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain IPT PF01745.11 AAS53559.2 - 0.45 9.6 1.8 20 4.2 0.0 2.7 3 0 0 3 3 3 0 Isopentenyl transferase AAA_23 PF13476.1 AAS53559.2 - 0.9 9.8 6.5 2.1 8.6 0.0 3.3 3 0 0 3 3 2 0 AAA domain Clp1 PF06807.9 AAS53560.1 - 0.00033 20.4 0.0 0.00088 19.0 0.0 1.7 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 AAS53560.1 - 0.0015 18.2 0.1 0.004 16.8 0.1 1.8 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 AAS53560.1 - 0.0028 17.5 0.2 0.0078 16.1 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 AAS53560.1 - 0.0064 16.6 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.15 AAS53560.1 - 0.059 12.0 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Arf PF00025.16 AAS53560.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Miro PF08477.8 AAS53560.1 - 0.16 12.4 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein zf-C2H2 PF00096.21 AAS53561.1 - 1.4e-05 25.1 20.5 0.0001 22.4 2.1 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AAS53561.1 - 0.00072 19.7 8.6 0.0023 18.1 1.8 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-met PF12874.2 AAS53561.1 - 0.012 15.8 2.5 0.022 14.9 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AAS53561.1 - 0.015 15.4 0.1 0.015 15.4 0.1 2.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 AAS53561.1 - 0.021 15.1 0.9 0.021 15.1 0.7 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 AAS53561.1 - 0.12 12.1 0.9 0.24 11.1 0.6 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type DUF629 PF04780.7 AAS53561.1 - 0.22 10.0 5.2 0.13 10.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) WSC PF01822.14 AAS53562.2 - 1.7e-10 40.6 6.4 1.7e-10 40.6 4.4 3.7 3 1 0 3 3 3 1 WSC domain DUF605 PF04652.11 AAS53562.2 - 0.45 9.8 29.5 0.58 9.5 20.4 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 AAS53562.2 - 2.8 6.1 29.9 4.3 5.4 20.7 1.3 1 0 0 1 1 1 0 Transmembrane protein RabGAP-TBC PF00566.13 AAS53563.2 - 0.0044 16.5 5.5 0.11 11.9 0.2 3.2 4 0 0 4 4 4 2 Rab-GTPase-TBC domain COX5B PF01215.14 AAS53564.1 - 9.4e-52 174.2 0.0 1.1e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Ribosomal_S26e PF01283.14 AAS53565.1 - 1.1e-51 173.8 10.1 1.3e-51 173.6 7.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1101 PF06503.6 AAS53565.1 - 0.02 13.7 0.1 0.021 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) SynMuv_product PF06047.6 AAS53565.1 - 0.076 12.7 0.1 0.13 12.0 0.1 1.4 1 1 0 1 1 1 0 Ras-induced vulval development antagonist Fer4_7 PF12838.2 AAS53565.1 - 0.15 12.4 2.5 0.26 11.6 0.3 2.1 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 AAS53565.1 - 0.27 11.0 3.5 0.24 11.2 0.5 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain WD40 PF00400.27 AAS53566.1 - 8.9e-18 63.4 1.2 0.0082 15.9 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat SGL PF08450.7 AAS53566.1 - 0.085 12.2 0.1 10 5.4 0.1 2.3 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region COX6A PF02046.10 AAS53567.1 - 3.2e-41 139.9 1.0 3.4e-41 139.8 0.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa TPR_12 PF13424.1 AAS53568.1 - 0.0002 21.2 4.0 1.3 9.0 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 AAS53568.1 - 0.18 12.1 2.5 0.72 10.2 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M3 PF01432.15 AAS53569.1 - 4.2e-131 438.1 0.0 5.4e-131 437.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 DUF770 PF05591.7 AAS53569.1 - 0.035 13.6 1.3 1.5 8.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF770) Peptidase_M50B PF13398.1 AAS53569.1 - 0.12 11.7 0.1 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like WD40 PF00400.27 AAS53570.1 - 2.7e-57 188.6 20.1 8.4e-11 41.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 AAS53570.1 - 8.9e-07 27.4 9.0 0.0017 16.6 0.5 3.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 AAS53570.1 - 0.00012 21.8 0.9 0.014 15.0 0.0 3.0 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 AAS53570.1 - 0.008 14.9 0.6 2.2 6.9 0.5 3.2 1 1 0 2 2 2 2 Nup133 N terminal like Adaptin_N PF01602.15 AAS53571.2 - 9.1e-122 407.0 16.0 1.2e-121 406.6 11.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 AAS53571.2 - 4.1e-19 69.1 3.0 4.1e-19 69.1 2.1 3.6 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 AAS53571.2 - 1.2e-12 47.8 0.5 2.7e-07 30.7 0.0 4.6 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.17 AAS53571.2 - 3.7e-10 38.9 0.4 0.0073 16.2 0.0 5.0 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 AAS53571.2 - 0.00045 20.6 0.5 4.6 7.8 0.0 4.6 4 0 0 4 4 4 2 HEAT-like repeat Atx10homo_assoc PF09759.4 AAS53571.2 - 0.18 11.5 1.6 1.1 9.0 0.1 3.0 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Cmc1 PF08583.5 AAS53572.1 - 1.9e-20 72.3 1.0 2.5e-20 71.9 0.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Kri1 PF05178.7 AAS53572.1 - 0.084 13.1 0.2 0.12 12.6 0.2 1.2 1 0 0 1 1 1 0 KRI1-like family COX17 PF05051.8 AAS53572.1 - 0.11 12.5 0.6 2.9 7.9 0.1 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) SAE2 PF08573.5 AAS53572.1 - 0.11 13.1 0.4 0.15 12.7 0.3 1.3 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Antimicrobial_6 PF08036.6 AAS53572.1 - 0.14 11.8 0.4 0.29 10.9 0.3 1.5 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide L31 PF09784.4 AAS53573.2 - 1.3e-42 144.0 3.0 2.8e-42 142.9 2.1 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L31 Spc24 PF08286.6 AAS53574.1 - 1.6e-27 95.5 0.1 1.6e-27 95.5 0.1 2.2 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Spc7 PF08317.6 AAS53574.1 - 0.0014 17.3 11.9 0.0018 17.0 8.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Peptidase_S46 PF10459.4 AAS53574.1 - 0.021 13.2 9.2 0.023 13.1 6.4 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF3755 PF12579.3 AAS53574.1 - 0.13 11.6 1.1 0.9 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) Tht1 PF04163.7 AAS53574.1 - 0.17 10.2 3.1 0.21 9.9 2.2 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein DUF955 PF06114.8 AAS53574.1 - 0.33 10.7 4.1 0.55 9.9 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF955) DUF4613 PF15390.1 AAS53574.1 - 0.6 8.2 6.1 0.71 7.9 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF1690 PF07956.6 AAS53574.1 - 0.84 9.6 12.8 0.54 10.2 7.7 1.5 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) DUF3103 PF11301.3 AAS53574.1 - 0.85 8.2 5.6 1.1 7.8 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) DUF3829 PF12889.2 AAS53574.1 - 1.6 7.8 7.9 2 7.5 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF342 PF03961.8 AAS53574.1 - 1.6 7.0 6.3 2 6.7 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 AAS53574.1 - 1.7 8.6 17.3 15 5.6 10.7 2.4 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain Enkurin PF13864.1 AAS53574.1 - 1.9 8.7 15.8 1.5 9.0 9.4 1.9 1 1 1 2 2 2 0 Calmodulin-binding Jnk-SapK_ap_N PF09744.4 AAS53574.1 - 3.6 7.5 16.1 0.8 9.6 9.0 1.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4200 PF13863.1 AAS53574.1 - 3.8 7.4 17.5 7.2 6.5 12.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Rtf2 PF04641.7 AAS53574.1 - 5.3 6.1 7.9 9.1 5.3 5.5 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger DUF2203 PF09969.4 AAS53574.1 - 7.3 6.8 7.9 8 6.7 4.7 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) V_ATPase_I PF01496.14 AAS53574.1 - 7.7 4.2 8.1 9.3 3.9 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 AAS53574.1 - 8.2 5.3 20.6 5.3 5.9 13.1 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 AAS53574.1 - 8.5 5.2 13.4 12 4.7 9.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HlyD PF00529.15 AAS53574.1 - 9.2 5.4 21.5 12 5.1 14.9 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DASH_Hsk3 PF08227.6 AAS53575.1 - 4e-20 71.7 5.4 5e-20 71.4 3.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like MCC-bdg_PDZ PF10506.4 AAS53575.1 - 0.048 13.4 1.5 0.18 11.6 1.1 1.9 1 1 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Atg14 PF10186.4 AAS53575.1 - 0.06 12.2 0.2 0.068 12.1 0.2 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Synaptonemal_3 PF15191.1 AAS53575.1 - 0.072 12.8 0.6 0.085 12.6 0.4 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 Flg_hook PF02120.11 AAS53575.1 - 0.11 12.1 1.0 0.19 11.4 0.7 1.3 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK CDC37_C PF08564.5 AAS53575.1 - 0.13 12.0 0.1 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 Cdc37 C terminal domain UPF0449 PF15136.1 AAS53575.1 - 0.23 11.6 0.9 0.26 11.5 0.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Pkinase PF00069.20 AAS53576.1 - 1.1e-72 244.3 0.0 1.4e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53576.1 - 3.8e-33 114.6 0.0 5e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS53576.1 - 0.00017 20.6 0.0 0.0004 19.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 AAS53576.1 - 0.0051 16.1 0.1 0.01 15.1 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 AAS53576.1 - 0.066 12.0 0.2 0.17 10.6 0.0 1.5 1 1 0 1 1 1 0 Seadornavirus VP7 Abhydrolase_1 PF00561.15 AAS53577.1 - 5.3e-20 71.9 0.1 6.7e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 AAS53577.1 - 3.2e-19 68.0 0.1 6.5e-19 67.0 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 AAS53577.1 - 4.6e-10 39.7 1.1 4.6e-10 39.7 0.7 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AAS53577.1 - 6.5e-06 25.9 0.1 0.00011 22.0 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 AAS53577.1 - 0.076 12.4 0.0 5.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Sdh_cyt PF01127.17 AAS53578.1 - 2e-26 92.2 2.7 2.5e-26 91.9 1.8 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PepSY_TM_3 PF13706.1 AAS53578.1 - 0.029 13.7 0.2 0.081 12.3 0.1 1.8 1 0 0 1 1 1 0 PepSY-associated TM helix HALZ PF02183.13 AAS53579.1 - 0.0014 18.3 0.6 0.0033 17.0 0.4 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper IFP_35_N PF07334.8 AAS53579.1 - 0.088 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DivIC PF04977.10 AAS53579.1 - 0.16 11.4 1.5 0.29 10.6 1.1 1.3 1 0 0 1 1 1 0 Septum formation initiator FlgN PF05130.7 AAS53579.1 - 0.17 12.1 1.1 0.23 11.7 0.2 1.6 2 0 0 2 2 2 0 FlgN protein bZIP_2 PF07716.10 AAS53579.1 - 1.3 8.8 6.4 0.13 12.0 1.0 1.9 2 0 0 2 2 2 0 Basic region leucine zipper Snf7 PF03357.16 AAS53580.1 - 1.9e-48 164.0 14.4 1.9e-48 164.0 10.0 1.9 2 0 0 2 2 2 1 Snf7 PspA_IM30 PF04012.7 AAS53580.1 - 0.011 15.1 14.4 0.12 11.7 10.0 2.3 1 1 0 1 1 1 0 PspA/IM30 family CHASE3 PF05227.8 AAS53580.1 - 0.033 13.8 6.9 0.06 13.0 4.5 1.6 1 1 0 1 1 1 0 CHASE3 domain NPV_P10 PF05531.7 AAS53580.1 - 0.21 11.8 6.0 30 4.9 2.6 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3573 PF12097.3 AAS53580.1 - 2.8 6.4 7.4 6.1 5.3 4.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Snapin_Pallidin PF14712.1 AAS53580.1 - 3.7 7.9 16.0 0.38 11.1 6.1 2.7 2 1 2 4 4 4 0 Snapin/Pallidin DUF342 PF03961.8 AAS53580.1 - 6.5 5.0 11.1 8.4 4.6 7.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) SNARE PF05739.14 AAS53581.2 - 9.6e-18 63.6 6.3 2.3e-17 62.4 1.6 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 AAS53581.2 - 1.1e-17 64.0 0.2 1.1e-17 64.0 0.2 2.7 2 1 0 2 2 2 1 Syntaxin Sed5p PF11416.3 AAS53581.2 - 9e-17 60.1 0.3 4e-15 54.9 0.0 2.5 2 0 0 2 2 2 1 Integral membrane protein Sed5p MCPsignal PF00015.16 AAS53581.2 - 0.00035 20.1 3.7 0.00054 19.5 0.2 2.5 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-18_N PF10496.4 AAS53581.2 - 0.00078 19.2 0.0 0.0025 17.6 0.0 1.8 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus IncA PF04156.9 AAS53581.2 - 0.0029 17.2 7.6 0.15 11.6 2.4 2.4 2 0 0 2 2 2 2 IncA protein DUF1664 PF07889.7 AAS53581.2 - 0.13 12.1 5.9 1 9.1 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 AAS53581.2 - 0.15 12.4 3.7 4.3 7.8 0.0 3.2 3 1 0 3 3 2 0 Syntaxin 6, N-terminal ATG16 PF08614.6 AAS53581.2 - 0.2 11.4 8.1 0.18 11.5 1.6 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Cluap1 PF10234.4 AAS53581.2 - 0.29 10.2 4.1 0.49 9.5 0.1 2.2 2 0 0 2 2 2 0 Clusterin-associated protein-1 Glutaredoxin2_C PF04399.8 AAS53581.2 - 0.32 10.5 4.1 2.3 7.7 0.1 3.0 3 1 0 3 3 3 0 Glutaredoxin 2, C terminal domain zf-C4H2 PF10146.4 AAS53581.2 - 1.7 8.6 6.1 0.35 10.8 0.5 2.2 2 1 0 2 2 2 0 Zinc finger-containing protein FlaC_arch PF05377.6 AAS53581.2 - 2 8.3 6.3 2.4 8.0 0.1 3.8 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) MRFAP1 PF15155.1 AAS53581.2 - 3.3 8.0 5.3 3.4 8.0 0.1 2.9 3 1 0 3 3 3 0 MORF4 family-associated protein1 WXG100 PF06013.7 AAS53581.2 - 7.8 6.5 11.4 1.2 9.1 0.9 2.8 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Aminotran_1_2 PF00155.16 AAS53582.1 - 3.3e-77 259.8 0.0 4.1e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II KAAG1 PF15354.1 AAS53582.1 - 0.054 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Kidney-associated antigen 1 zf-C3HC4_3 PF13920.1 AAS53583.2 - 1.6e-06 27.6 11.6 1.6e-06 27.6 8.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS53583.2 - 8.5 6.4 17.6 3.5 7.7 10.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AICARFT_IMPCHas PF01808.13 AAS53584.2 - 4.5e-120 400.4 0.0 6.3e-120 400.0 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 AAS53584.2 - 1.4e-24 85.8 0.1 4.2e-24 84.3 0.0 1.9 2 0 0 2 2 2 1 MGS-like domain Ribosomal_L15e PF00827.12 AAS53585.1 - 2.1e-89 298.1 14.1 2.4e-89 297.9 9.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 MSP1_C PF07462.6 AAS53586.1 - 3.3 5.9 8.3 3.3 5.9 5.7 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Pkr1 PF08636.5 AAS53587.1 - 2.7e-31 107.4 6.3 3.2e-31 107.1 4.4 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Rhomboid PF01694.17 AAS53587.1 - 0.018 15.0 1.4 0.021 14.8 1.0 1.1 1 0 0 1 1 1 0 Rhomboid family DUF4131 PF13567.1 AAS53587.1 - 0.071 12.5 2.9 0.079 12.3 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MASE2 PF05230.6 AAS53587.1 - 0.83 9.6 4.5 1.8 8.5 3.1 1.5 1 1 0 1 1 1 0 MASE2 domain CcoS PF03597.10 AAS53587.1 - 1.8 8.1 7.8 4.6 6.7 0.6 2.2 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF3329 PF11808.3 AAS53587.1 - 9.3 6.4 7.6 5.2 7.2 1.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3329) MIF4G_like_2 PF09090.6 AAS53589.2 - 1.4e-58 198.0 4.8 1.4e-58 198.0 3.3 1.6 2 0 0 2 2 2 1 MIF4G like MIF4G_like PF09088.6 AAS53589.2 - 1.5e-58 197.3 1.3 4.4e-58 195.8 0.9 1.7 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 AAS53589.2 - 8.3e-15 54.7 3.1 8.3e-15 54.7 2.2 2.7 4 0 0 4 4 4 1 MIF4G domain DUF4129 PF13559.1 AAS53590.1 - 0.0053 16.6 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) SNF2_N PF00176.18 AAS53591.2 - 1.6e-66 224.1 0.0 3.5e-66 223.0 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain HIRAN PF08797.6 AAS53591.2 - 3.9e-13 49.2 0.0 8.4e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 AAS53591.2 - 6.3e-11 41.9 0.0 1.6e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 AAS53591.2 - 4.6e-07 29.5 9.7 8.9e-07 28.6 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AAS53591.2 - 1.4e-05 24.5 11.6 2.8e-05 23.6 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS53591.2 - 5.1e-05 23.2 11.4 0.00011 22.1 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AAS53591.2 - 9.1e-05 22.1 10.5 0.00018 21.1 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 AAS53591.2 - 0.012 15.4 2.3 0.025 14.3 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 AAS53591.2 - 0.094 12.8 3.7 0.2 11.7 2.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 AAS53591.2 - 0.1 12.3 5.7 0.3 10.8 4.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 AAS53591.2 - 0.46 10.0 5.6 1.3 8.6 3.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 AAS53591.2 - 0.84 9.6 6.6 2.1 8.3 4.6 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 AAS53591.2 - 1.2 8.7 7.9 3.6 7.2 5.5 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 AAS53591.2 - 1.3 8.9 11.0 2.7 7.9 7.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING MOZ_SAS PF01853.13 AAS53592.1 - 1.5e-61 206.9 0.6 2.1e-61 206.4 0.4 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-C2H2 PF00096.21 AAS53592.1 - 0.0024 18.1 2.2 0.0054 16.9 0.4 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type HA2 PF04408.18 AAS53593.2 - 4.3e-26 90.8 0.3 4.2e-25 87.7 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AAS53593.2 - 4e-14 52.2 0.0 4.6e-13 48.8 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 AAS53593.2 - 4.9e-11 42.4 0.0 1.4e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 AAS53593.2 - 2.1e-08 33.8 0.0 5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AAS53593.2 - 1e-05 25.6 0.2 4.4e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 AAS53593.2 - 0.00061 18.9 0.0 0.0017 17.5 0.0 1.7 1 0 0 1 1 1 1 KaiC T2SE PF00437.15 AAS53593.2 - 0.013 14.4 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 AAS53593.2 - 0.03 14.2 0.1 0.51 10.2 0.1 2.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AAS53593.2 - 0.048 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 AAS53593.2 - 0.052 13.3 0.0 0.052 13.3 0.0 4.7 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit PhoH PF02562.11 AAS53593.2 - 0.058 12.6 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Bromodomain PF00439.20 AAS53594.2 - 0.00023 21.0 0.0 0.00065 19.5 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Nramp PF01566.13 AAS53595.1 - 1.3e-96 323.5 17.3 1.6e-96 323.2 12.0 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Wzy_C PF04932.10 AAS53595.1 - 0.03 14.1 0.3 0.03 14.1 0.2 3.2 3 1 0 3 3 3 0 O-Antigen ligase HATPase_c_3 PF13589.1 AAS53597.1 - 3.2e-11 43.0 0.0 8e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 AAS53597.1 - 2.9e-10 39.6 0.0 6.7e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 AAS53597.1 - 6.1e-09 35.5 0.1 1.3e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAD_2 PF13419.1 AAS53598.2 - 3.1e-19 69.8 0.0 3.8e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AAS53598.2 - 9.5e-07 28.4 0.0 1.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like PTR2 PF00854.16 AAS53599.1 - 2.3e-28 99.0 2.6 4.8e-28 98.0 1.8 1.5 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 AAS53599.1 - 1.4e-10 40.4 18.2 8.7e-06 24.6 0.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 AAS53600.1 - 2.2e-10 39.8 21.2 3.8e-10 39.0 14.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Pox_P21 PF05313.7 AAS53600.1 - 0.48 9.6 3.7 20 4.3 0.2 3.3 3 0 0 3 3 3 0 Poxvirus P21 membrane protein AA_permease PF00324.16 AAS53601.1 - 3.8e-139 464.1 31.9 4.3e-139 463.9 22.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS53601.1 - 3.8e-44 150.8 31.5 5.1e-44 150.4 21.8 1.1 1 0 0 1 1 1 1 Amino acid permease PT PF04886.7 AAS53602.1 - 1.5 8.2 14.7 0.063 12.6 4.2 2.8 3 0 0 3 3 3 0 PT repeat ABC_tran PF00005.22 AAS53603.2 - 2.2e-49 167.2 0.0 2.6e-24 86.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AAS53603.2 - 2.5e-21 76.9 1.9 2.9e-05 24.1 0.1 4.4 2 2 0 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 AAS53603.2 - 2.6e-21 75.2 2.0 2.6e-21 75.2 1.4 2.8 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 AAS53603.2 - 1.2e-09 37.7 1.6 0.41 9.8 0.0 4.6 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AAS53603.2 - 1.7e-09 37.0 0.0 0.00025 20.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AAS53603.2 - 2.9e-09 37.5 2.2 0.0067 16.7 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 AAS53603.2 - 1.2e-08 35.2 0.0 0.0053 16.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 AAS53603.2 - 7.7e-08 32.7 0.2 0.016 15.5 0.0 3.9 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 AAS53603.2 - 1.7e-07 32.1 0.2 0.0022 18.7 0.0 3.5 3 1 0 3 3 2 2 AAA domain DUF258 PF03193.11 AAS53603.2 - 2.9e-07 29.8 0.0 0.00029 20.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 AAS53603.2 - 1.9e-06 28.3 0.0 0.011 16.2 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA PF00004.24 AAS53603.2 - 1.8e-05 24.9 0.1 0.24 11.5 0.0 3.5 2 2 1 3 3 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AAS53603.2 - 5e-05 23.0 1.6 0.15 11.7 0.0 2.9 3 1 0 3 3 2 2 NACHT domain AAA_33 PF13671.1 AAS53603.2 - 6.9e-05 22.7 0.3 0.17 11.7 0.0 3.4 4 0 0 4 4 3 1 AAA domain Arch_ATPase PF01637.13 AAS53603.2 - 7e-05 22.6 0.7 0.33 10.6 0.0 3.4 4 0 0 4 4 3 2 Archaeal ATPase MMR_HSR1 PF01926.18 AAS53603.2 - 7.1e-05 22.7 0.0 0.25 11.2 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 AAS53603.2 - 8.7e-05 22.0 0.6 0.24 10.7 0.1 3.1 3 1 0 3 3 3 2 AAA-like domain RNA_helicase PF00910.17 AAS53603.2 - 9.2e-05 22.5 0.0 0.58 10.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_15 PF13175.1 AAS53603.2 - 9.3e-05 21.6 0.0 0.54 9.2 0.0 3.2 4 1 0 4 4 3 2 AAA ATPase domain AAA_14 PF13173.1 AAS53603.2 - 0.00015 21.6 0.0 0.53 10.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AAS53603.2 - 0.00015 21.8 0.8 0.85 9.5 0.2 3.1 3 1 0 3 3 2 2 AAA ATPase domain AAA_25 PF13481.1 AAS53603.2 - 0.00031 20.2 0.1 0.38 10.1 0.1 3.2 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 AAS53603.2 - 0.00041 20.0 0.3 0.012 15.3 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 AAS53603.2 - 0.00094 19.1 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 AAS53603.2 - 0.0019 17.6 0.1 0.72 9.2 0.0 2.9 3 0 0 3 3 3 1 Virulence-associated protein E MCM PF00493.18 AAS53603.2 - 0.0025 16.6 1.3 0.3 9.8 0.0 2.9 3 0 0 3 3 3 1 MCM2/3/5 family Dynamin_N PF00350.18 AAS53603.2 - 0.0046 16.8 0.4 1.6 8.4 0.0 3.5 2 1 1 3 3 3 1 Dynamin family NB-ARC PF00931.17 AAS53603.2 - 0.0055 15.5 0.0 1.9 7.3 0.0 2.8 2 1 0 2 2 2 1 NB-ARC domain ArgK PF03308.11 AAS53603.2 - 0.0062 15.3 0.1 0.84 8.3 0.0 2.8 3 0 0 3 3 3 1 ArgK protein SbcCD_C PF13558.1 AAS53603.2 - 0.0064 16.3 0.3 1.1 9.2 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 AAS53603.2 - 0.0075 15.9 0.1 4.4 7.0 0.1 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 AAS53603.2 - 0.025 13.5 0.0 8.2 5.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 AAS53603.2 - 0.032 13.9 0.1 3 7.5 0.1 2.6 2 0 0 2 2 2 0 NTPase DAP3 PF10236.4 AAS53603.2 - 0.046 12.6 0.9 9.3 5.0 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Rad17 PF03215.10 AAS53603.2 - 0.062 11.9 0.1 6.5 5.3 0.0 2.6 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein PduV-EutP PF10662.4 AAS53603.2 - 0.068 12.6 0.0 29 4.1 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 AAS53603.2 - 2 8.1 8.1 13 5.5 0.0 3.7 4 1 1 5 5 4 0 Domain of unknown function DUF87 BRF1 PF07741.8 AAS53603.2 - 3.2 8.0 10.2 0.16 12.1 2.4 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain HAD_2 PF13419.1 AAS53605.2 - 2.1e-25 89.9 0.1 2.7e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AAS53605.2 - 0.00015 22.2 0.0 0.00091 19.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Nse5 PF08691.5 AAS53606.1 - 2.1e-80 270.6 3.2 2.4e-80 270.5 2.2 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 UAA PF08449.6 AAS53607.2 - 1.6e-17 63.4 24.0 1.9e-17 63.1 16.6 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 AAS53607.2 - 1e-08 34.9 8.3 1e-08 34.9 5.8 2.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 AAS53607.2 - 0.00069 19.6 31.3 0.014 15.4 7.6 2.4 2 0 0 2 2 2 2 EamA-like transporter family DUF2238 PF09997.4 AAS53607.2 - 0.21 10.9 5.6 0.049 13.0 1.0 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2238) PHO4 PF01384.15 AAS53607.2 - 1.6 7.2 12.6 0.076 11.6 2.3 2.6 1 1 1 2 2 2 0 Phosphate transporter family Multi_Drug_Res PF00893.14 AAS53607.2 - 2.3 8.7 17.0 2.8 8.4 5.3 3.0 2 1 0 2 2 2 0 Small Multidrug Resistance protein GATA PF00320.22 AAS53608.2 - 1e-14 53.5 2.9 2.2e-14 52.4 2.0 1.6 1 0 0 1 1 1 1 GATA zinc finger XPG_I PF00867.13 AAS53609.1 - 1.5e-21 76.2 0.0 3.3e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 AAS53609.1 - 0.013 15.6 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 XPG N-terminal domain CHASE4 PF05228.8 AAS53609.1 - 0.05 13.1 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 CHASE4 domain PMSR PF01625.16 AAS53610.2 - 3.4e-49 166.7 0.0 4.2e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase COX4 PF02936.9 AAS53611.1 - 4.6e-09 36.1 0.0 5.4e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV MFS_Mycoplasma PF07672.8 AAS53612.2 - 0.099 11.7 1.1 0.12 11.5 0.8 1.0 1 0 0 1 1 1 0 Mycoplasma MFS transporter SPRY PF00622.23 AAS53613.1 - 9.6e-22 77.3 0.0 2.4e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 AAS53613.1 - 2.2e-12 46.9 2.1 3.4e-12 46.2 1.5 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 AAS53613.1 - 0.018 14.7 0.0 0.043 13.5 0.0 1.7 1 0 0 1 1 1 0 LisH AdoHcyase PF05221.12 AAS53614.1 - 6e-142 471.3 0.1 7e-142 471.1 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 AAS53614.1 - 4.7e-85 283.4 1.9 7.4e-85 282.7 1.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 AAS53614.1 - 5.5e-08 32.1 0.1 1.6e-07 30.6 0.1 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 AAS53614.1 - 0.0016 17.8 0.1 0.0027 17.0 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 AAS53614.1 - 0.0017 18.3 0.1 0.0036 17.2 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 AAS53614.1 - 0.026 14.0 0.1 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 AAS53614.1 - 0.075 12.5 0.3 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF651 PF04895.7 AAS53615.1 - 0.012 15.2 1.1 3.7 7.2 0.0 3.5 3 0 0 3 3 3 0 Archaeal protein of unknown function (DUF651) YbjQ_1 PF01906.12 AAS53615.1 - 0.026 14.9 0.1 5.9 7.3 0.0 3.0 2 0 0 2 2 2 0 Putative heavy-metal-binding RGS PF00615.14 AAS53615.1 - 0.41 10.7 4.9 3.7 7.6 1.4 3.0 2 1 0 2 2 2 0 Regulator of G protein signaling domain SAPS PF04499.10 AAS53616.2 - 3.1e-167 557.0 7.9 4.7e-167 556.4 5.5 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein DnaJ PF00226.26 AAS53617.1 - 2.2e-11 43.3 3.5 4.1e-11 42.4 2.4 1.5 1 0 0 1 1 1 1 DnaJ domain Adaptin_binding PF10199.4 AAS53619.1 - 5.9e-08 33.0 1.1 0.0038 17.4 0.1 2.3 1 1 1 2 2 2 2 Alpha and gamma adaptin binding protein p34 DUF3110 PF11360.3 AAS53619.1 - 0.019 14.7 0.1 0.057 13.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) DUF1077 PF06417.7 AAS53620.1 - 3e-48 162.3 2.1 3.8e-48 161.9 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) CopD PF05425.8 AAS53620.1 - 0.0053 16.9 1.7 0.0077 16.4 1.2 1.2 1 0 0 1 1 1 1 Copper resistance protein D THUMP PF02926.12 AAS53621.1 - 6.4e-23 81.2 0.9 6.4e-23 81.2 0.6 1.7 1 1 1 2 2 2 1 THUMP domain Drc1-Sld2 PF11719.3 AAS53621.1 - 0.045 12.8 2.0 0.064 12.3 1.4 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein ARD PF03079.9 AAS53621.1 - 0.18 11.7 0.0 0.18 11.7 0.0 2.4 2 1 0 3 3 3 0 ARD/ARD' family Sec15 PF04091.7 AAS53622.2 - 9.7e-111 370.0 14.7 9.7e-111 370.0 10.2 3.1 4 0 0 4 4 4 1 Exocyst complex subunit Sec15-like Peptidase_M20 PF01546.23 AAS53623.1 - 1.3e-29 103.0 0.0 2.4e-29 102.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AAS53623.1 - 1.2e-12 47.5 0.0 2.1e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 AAS53623.1 - 0.0023 17.7 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Mito_carr PF00153.22 AAS53624.1 - 1.1e-40 137.2 4.2 1.1e-20 73.1 0.1 4.5 3 2 0 3 3 3 3 Mitochondrial carrier protein GARS_A PF01071.14 AAS53625.2 - 2.2e-79 265.5 0.0 3.2e-79 265.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 AAS53625.2 - 2.2e-35 121.1 0.2 1.4e-34 118.5 0.0 2.5 4 0 0 4 4 4 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 AAS53625.2 - 4.8e-32 111.0 0.0 1.2e-31 109.7 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 AAS53625.2 - 1.1e-25 89.5 0.2 2.7e-25 88.3 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 AAS53625.2 - 9e-17 61.1 2.7 3.7e-16 59.1 1.3 2.5 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 AAS53625.2 - 5e-13 49.1 0.1 2.2e-10 40.5 0.0 3.0 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AAS53625.2 - 2.9e-08 32.8 0.0 6.6e-08 31.6 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AAS53625.2 - 1.2e-06 27.9 0.0 2.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 AAS53625.2 - 0.00014 21.7 0.0 0.00063 19.6 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AAS53625.2 - 0.00088 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 AAS53625.2 - 0.0079 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GIDA PF01134.17 AAS53626.2 - 2.4e-149 497.5 0.0 3.1e-149 497.1 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 AAS53626.2 - 3.7e-20 71.7 0.6 1.9e-19 69.4 0.1 2.3 3 0 0 3 3 3 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 AAS53626.2 - 9.6e-06 25.6 0.1 2e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AAS53626.2 - 3.6e-05 22.8 5.7 0.0016 17.4 0.1 2.9 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AAS53626.2 - 0.00026 19.9 4.5 0.031 13.1 1.9 2.5 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 AAS53626.2 - 0.00032 19.9 0.7 0.00059 19.0 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AAS53626.2 - 0.0015 18.8 0.2 0.0042 17.4 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AAS53626.2 - 0.0085 16.1 0.1 0.22 11.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AAS53626.2 - 0.066 11.6 2.9 1.8 6.9 1.1 2.3 2 0 0 2 2 2 0 HI0933-like protein CBFB_NFYA PF02045.10 AAS53628.1 - 2.1e-27 95.3 9.2 4e-27 94.5 6.3 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Proteasome PF00227.21 AAS53629.1 - 4.5e-21 74.9 0.1 5.6e-21 74.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit PDEase_II PF02112.10 AAS53630.1 - 7.8e-58 195.9 0.0 1.2e-57 195.4 0.0 1.3 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 AAS53630.1 - 6.6e-11 42.1 0.0 8.7e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF2638 PF10937.3 AAS53631.1 - 2.5e-30 105.7 0.0 2.9e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Brr6_like_C_C PF10104.4 AAS53632.1 - 9.3e-40 135.2 0.1 1.1e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain ABC_tran PF00005.22 AAS53632.1 - 0.14 12.4 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 ABC transporter RAI1 PF08652.6 AAS53633.1 - 5.2e-39 131.8 2.5 1.7e-20 72.5 0.1 2.4 2 0 0 2 2 2 2 RAI1 like PD-(D/E)XK nuclease RAI1 PF08652.6 AAS53634.1 - 3.3e-26 90.8 0.3 6e-26 90.0 0.2 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease tRNA-synt_1c PF00749.16 AAS53635.2 - 6e-117 389.7 0.1 7.6e-117 389.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 AAS53635.2 - 1.6e-37 128.8 0.0 3.2e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 AAS53635.2 - 2.5e-07 31.1 0.0 7.7e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 AAS53635.2 - 5.2e-05 23.0 0.0 0.00018 21.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AAS53635.2 - 0.00084 19.2 0.0 0.0025 17.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 AAS53635.2 - 0.095 11.7 0.1 0.17 10.9 0.1 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DUF155 PF02582.9 AAS53636.2 - 3.2e-59 199.7 0.0 6.6e-59 198.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Plus-3 PF03126.13 AAS53637.1 - 9.6e-36 122.1 0.2 9.6e-36 122.1 0.2 2.5 3 0 0 3 3 3 1 Plus-3 domain Lyase_8_C PF02884.12 AAS53637.1 - 0.035 14.1 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain A_deamin PF02137.13 AAS53638.1 - 6e-62 209.9 0.0 7.3e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain APOBEC_N PF08210.6 AAS53638.1 - 3.8e-05 23.3 0.0 0.0006 19.4 0.0 2.3 2 0 0 2 2 2 1 APOBEC-like N-terminal domain dCMP_cyt_deam_1 PF00383.17 AAS53638.1 - 0.18 11.4 2.3 0.24 11.0 0.1 2.4 3 1 0 3 3 3 0 Cytidine and deoxycytidylate deaminase zinc-binding region Ank PF00023.25 AAS53639.1 - 3.1e-10 39.3 0.7 0.00072 19.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 AAS53639.1 - 3.1e-10 40.2 0.1 4.7e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AAS53639.1 - 5.8e-09 36.2 0.3 3.5e-05 24.1 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AAS53639.1 - 1.4e-08 34.1 0.5 0.023 14.9 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 AAS53639.1 - 1.4e-08 34.6 3.2 0.003 17.7 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) IBN_N PF03810.14 AAS53640.3 - 1.8e-07 30.9 0.0 2e-06 27.6 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Atx10homo_assoc PF09759.4 AAS53640.3 - 0.026 14.2 0.4 0.41 10.4 0.2 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain ArsD PF06953.6 AAS53641.2 - 0.02 15.0 0.2 4.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Arsenical resistance operon trans-acting repressor ArsD MCM_N PF14551.1 AAS53641.2 - 0.093 13.2 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 MCM N-terminal domain QRPTase_C PF01729.14 AAS53642.2 - 6.3e-57 191.7 0.0 8e-57 191.4 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 AAS53642.2 - 6.7e-23 80.3 0.0 1.6e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain TMP-TENI PF02581.12 AAS53642.2 - 0.057 12.5 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI APC10 PF03256.11 AAS53643.1 - 1.8e-55 187.5 0.0 2.1e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 AAS53643.1 - 0.00047 19.9 0.1 0.0009 19.0 0.0 1.6 1 1 0 1 1 1 1 F5/8 type C domain Cse1 PF08506.5 AAS53644.2 - 3.3e-175 582.0 9.0 3.3e-175 582.0 6.3 1.6 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.10 AAS53644.2 - 1.2e-105 353.3 4.7 1.2e-105 353.3 3.2 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 AAS53644.2 - 2.7e-15 56.0 0.1 5.9e-14 51.7 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 AAS53644.2 - 0.0005 20.0 0.9 0.073 12.9 0.0 4.1 4 2 0 4 4 4 1 Exportin 1-like protein UME PF08064.8 AAS53644.2 - 0.065 13.1 1.9 2.4 8.1 0.0 4.0 4 0 0 4 4 4 0 UME (NUC010) domain Adap_comp_sub PF00928.16 AAS53645.1 - 7.4e-10 38.3 0.4 1.1e-09 37.7 0.3 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AAS53645.1 - 2e-07 30.7 0.5 5.1e-07 29.5 0.3 1.7 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-RING_2 PF13639.1 AAS53646.1 - 4e-10 39.3 6.2 9.7e-10 38.1 4.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AAS53646.1 - 4e-07 29.6 4.4 7.8e-07 28.7 3.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 AAS53646.1 - 1.1e-06 28.6 8.8 2.3e-06 27.6 6.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 AAS53646.1 - 1.4e-06 27.7 6.8 4.1e-06 26.3 4.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AAS53646.1 - 6.1e-06 25.8 6.1 1.4e-05 24.7 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS53646.1 - 0.00033 20.6 7.4 0.002 18.0 4.7 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AAS53646.1 - 0.018 14.8 3.0 0.044 13.6 2.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Trm112p PF03966.11 AAS53646.1 - 0.15 12.4 0.7 9.1 6.7 0.0 2.7 2 0 0 2 2 2 0 Trm112p-like protein FANCL_C PF11793.3 AAS53646.1 - 0.2 11.6 5.5 0.8 9.7 3.8 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain DUF2420 PF10336.4 AAS53647.2 - 4.1e-43 145.5 0.1 6.1e-43 145.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Ppx-GppA PF02541.11 AAS53648.1 - 9.9e-66 221.8 0.0 1.3e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family DUF1699 PF08004.6 AAS53648.1 - 0.0098 15.4 0.1 0.044 13.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1699) SAC3_GANP PF03399.11 AAS53649.1 - 2.2e-29 102.5 0.4 2.8e-29 102.1 0.3 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 AAS53649.1 - 9.7e-20 70.7 0.3 1.5e-19 70.2 0.2 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Hexokinase_2 PF03727.11 AAS53650.1 - 1.9e-97 325.2 0.0 3.1e-97 324.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 AAS53650.1 - 1.5e-84 282.4 0.0 2.1e-84 281.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 AAS53650.1 - 0.026 13.8 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain MiAMP1 PF09117.5 AAS53650.1 - 0.1 12.9 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 MiAMP1 Helicase_C_3 PF13625.1 AAS53651.1 - 1.3e-26 92.9 0.0 4.9e-26 90.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS53651.1 - 1.3e-13 51.2 0.0 2.2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 AAS53651.1 - 6.5e-12 44.8 0.0 9.7e-12 44.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AAS53651.1 - 3.3e-10 39.6 0.0 7.5e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AAS53651.1 - 7.6e-07 28.7 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.1 AAS53651.1 - 0.016 14.5 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Ndc80_HEC PF03801.8 AAS53652.2 - 5e-56 188.5 0.1 1.3e-55 187.1 0.1 1.7 1 0 0 1 1 1 1 HEC/Ndc80p family Spc7 PF08317.6 AAS53652.2 - 8.4e-06 24.6 37.9 0.00013 20.7 12.6 2.7 2 1 0 2 2 2 2 Spc7 kinetochore protein DUF4200 PF13863.1 AAS53652.2 - 0.00029 20.7 5.1 0.00029 20.7 3.5 5.1 3 2 2 5 5 5 1 Domain of unknown function (DUF4200) DUF3584 PF12128.3 AAS53652.2 - 0.00082 16.8 24.0 0.0032 14.8 5.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) DASH_Spc34 PF08657.5 AAS53652.2 - 0.00087 19.0 12.4 0.00087 19.0 8.6 2.6 1 1 2 3 3 3 1 DASH complex subunit Spc34 Baculo_PEP_C PF04513.7 AAS53652.2 - 0.007 16.1 21.2 0.016 14.9 1.7 4.5 5 0 0 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus Lipoprotein_20 PF13942.1 AAS53652.2 - 0.0074 15.8 2.9 0.0074 15.8 2.0 3.6 3 1 1 4 4 4 2 YfhG lipoprotein Reo_sigmaC PF04582.7 AAS53652.2 - 0.0091 15.2 9.9 0.13 11.4 0.9 2.7 1 1 0 2 2 2 2 Reovirus sigma C capsid protein NPV_P10 PF05531.7 AAS53652.2 - 0.031 14.5 20.8 0.07 13.3 0.1 5.5 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein CARD PF00619.16 AAS53652.2 - 0.063 13.1 5.3 0.033 14.0 0.8 2.7 3 0 0 3 3 2 0 Caspase recruitment domain Cluap1 PF10234.4 AAS53652.2 - 0.26 10.4 35.0 4.1 6.5 11.7 4.8 3 2 2 5 5 5 0 Clusterin-associated protein-1 Filament PF00038.16 AAS53652.2 - 0.29 10.5 29.5 0.94 8.8 5.3 2.7 2 1 1 3 3 3 0 Intermediate filament protein HrpB7 PF09486.5 AAS53652.2 - 0.64 9.9 12.1 1.8 8.4 0.1 3.4 2 2 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) TPR_MLP1_2 PF07926.7 AAS53652.2 - 1.1 9.0 32.9 22 4.8 5.7 4.8 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein Sec2p PF06428.6 AAS53652.2 - 1.4 8.7 23.8 0.36 10.7 1.8 4.2 2 2 2 4 4 4 0 GDP/GTP exchange factor Sec2p IncA PF04156.9 AAS53652.2 - 6.5 6.3 43.8 2.4 7.7 13.1 4.7 3 2 2 5 5 5 0 IncA protein Pantoate_ligase PF02569.10 AAS53653.2 - 3.3e-102 341.0 0.0 3.7e-102 340.8 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase HATPase_c PF02518.21 AAS53655.2 - 2.7e-28 97.8 0.3 9.4e-28 96.1 0.2 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 AAS53655.2 - 3.3e-26 91.4 0.1 6.3e-26 90.5 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 AAS53655.2 - 1.1e-11 44.5 0.2 3e-11 43.1 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 AAS53655.2 - 1.8e-06 28.0 2.2 0.015 15.4 0.0 3.2 3 0 0 3 3 3 2 HAMP domain Git3 PF11710.3 AAS53655.2 - 0.067 12.7 1.0 0.14 11.7 0.7 1.4 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Bindin PF02084.10 AAS53655.2 - 0.13 12.3 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Bindin ubiquitin PF00240.18 AAS53656.1 - 6.2e-35 118.4 0.7 8.2e-35 118.0 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 AAS53656.1 - 3.7e-31 106.4 11.3 5.9e-31 105.8 7.8 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 AAS53656.1 - 5.4e-20 70.8 0.7 8.8e-20 70.1 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AAS53656.1 - 8.3e-06 25.9 0.1 3e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 AAS53656.1 - 0.00017 21.3 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 AAS53656.1 - 0.005 16.7 0.1 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AAS53656.1 - 0.015 15.4 0.1 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Fer2_3 PF13085.1 AAS53656.1 - 0.14 11.9 1.7 0.58 10.0 1.2 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain TPR_MLP1_2 PF07926.7 AAS53657.1 - 2e-27 95.5 28.9 2e-27 95.5 20.0 16.5 9 5 5 15 15 15 6 TPR/MLP1/MLP2-like protein zf-primase PF09329.6 AAS53658.1 - 1.1e-14 53.7 0.1 2.5e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 Primase zinc finger BRCA-2_OB1 PF09103.5 AAS53658.1 - 0.016 14.9 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 tRNA_anti-codon PF01336.20 AAS53658.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DAGK_cat PF00781.19 AAS53659.2 - 1.1e-08 34.6 0.1 2.6e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Fucokinase PF07959.7 AAS53659.2 - 0.13 10.8 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase Pcc1 PF09341.5 AAS53660.1 - 6.6e-23 80.5 0.4 7.2e-23 80.4 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 PIN_4 PF13638.1 AAS53661.2 - 1.1e-11 44.9 1.2 1.7e-11 44.3 0.1 1.9 2 0 0 2 2 2 1 PIN domain Acetyltransf_11 PF13720.1 AAS53661.2 - 0.1 12.8 0.2 1.8 8.8 0.0 2.7 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Tmemb_cc2 PF10267.4 AAS53661.2 - 0.11 11.0 2.5 0.19 10.2 1.7 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF2656 PF10847.3 AAS53662.1 - 0.015 15.2 0.1 3.4 7.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2656) PEPCK_ATP PF01293.15 AAS53663.1 - 5.6e-218 724.1 0.0 7e-218 723.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 AAS53663.1 - 0.005 16.7 0.0 0.012 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AAS53663.1 - 0.096 12.2 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 AAS53663.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 AAS53663.1 - 0.16 11.3 0.0 0.54 9.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain PTPA PF03095.10 AAS53664.1 - 4e-110 367.6 0.0 4.6e-110 367.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DAO PF01266.19 AAS53666.2 - 2.9e-50 171.1 0.0 3.7e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AAS53666.2 - 2.8e-13 49.5 1.4 8.4e-13 47.9 1.0 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 AAS53666.2 - 7.5e-10 38.4 2.4 4e-06 26.1 0.1 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 AAS53666.2 - 1.9e-05 23.8 0.4 0.037 13.1 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 AAS53666.2 - 2.6e-05 23.2 0.3 0.0046 15.8 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 AAS53666.2 - 0.00021 20.4 0.1 0.29 10.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 AAS53666.2 - 0.00059 19.7 0.1 0.027 14.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AAS53666.2 - 0.00079 17.9 0.3 0.0013 17.3 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 AAS53666.2 - 0.0012 18.7 0.4 0.0032 17.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.14 AAS53666.2 - 0.11 11.6 0.1 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 GMC oxidoreductase 3HCDH_N PF02737.13 AAS53666.2 - 0.13 11.8 0.8 0.73 9.4 0.6 2.2 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UCH PF00443.24 AAS53667.2 - 1.8e-55 187.9 5.2 2.7e-55 187.3 3.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AAS53667.2 - 1.3e-27 97.0 4.6 2.3e-27 96.2 3.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 AAS53667.2 - 0.00019 21.7 0.0 0.00046 20.5 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Myb_DNA-bind_6 PF13921.1 AAS53668.1 - 1.3e-27 95.6 7.1 6.9e-11 42.0 0.0 4.1 2 1 2 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AAS53668.1 - 1.1e-23 82.9 10.2 5.5e-10 39.1 0.2 4.1 3 1 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 AAS53668.1 - 0.0013 18.5 2.5 1.6 8.7 0.3 3.3 1 1 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF1748 PF08520.5 AAS53669.1 - 4.5e-30 103.1 0.1 4.9e-30 102.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Coa1 PF08695.5 AAS53670.1 - 3e-35 120.2 0.0 3.7e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 SKG6 PF08693.5 AAS53671.1 - 0.00092 18.4 3.4 0.0017 17.6 2.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1049 PF06305.6 AAS53671.1 - 0.069 12.6 0.1 0.66 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) HrpF PF06266.7 AAS53671.1 - 0.074 13.1 0.5 0.22 11.6 0.3 1.7 1 0 0 1 1 1 0 HrpF protein GRAS PF03514.9 AAS53671.1 - 0.15 10.7 0.7 0.24 10.0 0.3 1.4 1 1 0 1 1 1 0 GRAS domain family DUF1180 PF06679.7 AAS53671.1 - 0.4 10.5 4.1 3.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TMEM154 PF15102.1 AAS53671.1 - 1.1 8.9 4.1 1.1 8.9 0.0 2.5 3 0 0 3 3 3 0 TMEM154 protein family CcmD PF04995.9 AAS53671.1 - 4.1 7.2 6.1 2.2 8.1 0.1 2.4 2 1 0 2 2 2 0 Heme exporter protein D (CcmD) FH2 PF02181.18 AAS53672.1 - 1.4e-66 224.9 5.0 1.4e-66 224.9 3.4 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 AAS53672.1 - 3.9e-07 29.6 0.0 3.9e-07 29.6 0.0 2.5 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 AAS53672.1 - 5.3e-05 22.7 0.1 5.3e-05 22.7 0.1 3.3 3 1 1 4 4 4 1 Diaphanous FH3 Domain YjcZ PF13990.1 AAS53672.1 - 0.16 11.0 7.7 0.052 12.6 3.1 1.8 2 0 0 2 2 2 0 YjcZ-like protein NPV_P10 PF05531.7 AAS53672.1 - 6.2 7.1 8.7 12 6.2 0.1 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Thiolase_N PF00108.18 AAS53673.1 - 2.6e-85 285.5 0.1 3.9e-85 285.0 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AAS53673.1 - 6.9e-47 157.8 0.7 1.3e-46 157.0 0.5 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 AAS53673.1 - 0.00064 19.2 0.1 0.0018 17.8 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 AAS53673.1 - 0.12 12.0 1.4 2.5 7.7 0.0 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Asn_synthase PF00733.16 AAS53674.1 - 2.1e-68 230.6 0.0 2.7e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 AAS53674.1 - 5.4e-33 113.3 0.0 8.8e-33 112.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 AAS53674.1 - 5.5e-27 94.3 0.0 1.3e-26 93.1 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 AAS53674.1 - 2.3e-05 23.7 0.0 3.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 AAS53674.1 - 0.0066 15.2 0.0 0.14 10.8 0.0 2.4 1 1 2 3 3 3 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 AAS53674.1 - 0.021 13.7 0.0 0.03 13.2 0.0 1.4 1 1 0 1 1 1 0 NAD synthase Sulfate_transp PF00916.15 AAS53675.2 - 2.5e-48 164.4 3.9 6.2e-48 163.2 2.7 1.7 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 AAS53675.2 - 3.9e-11 42.3 1.1 8.7e-11 41.2 0.8 1.6 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.24 AAS53675.2 - 2.3e-05 24.1 0.0 5.8e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain NRDE PF05742.7 AAS53676.1 - 9.1e-49 166.1 0.0 1.1e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 NRDE protein SAMP PF05924.6 AAS53676.1 - 0.086 12.0 0.1 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 SAMP Motif DUF2305 PF10230.4 AAS53677.1 - 2.1e-78 263.4 0.1 2.5e-78 263.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 AAS53677.1 - 1e-07 32.0 0.0 1.3e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AAS53677.1 - 0.00012 21.8 0.0 0.00019 21.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 AAS53677.1 - 0.0011 18.6 0.2 0.0023 17.5 0.1 1.5 1 1 0 1 1 1 1 PGAP1-like protein DUF4206 PF13901.1 AAS53677.1 - 0.008 15.7 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) Thioesterase PF00975.15 AAS53677.1 - 0.017 15.3 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 AAS53677.1 - 0.029 13.9 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Lipase_2 PF01674.13 AAS53677.1 - 0.048 12.9 0.0 5.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 2) Utp8 PF10395.4 AAS53678.1 - 2.1e-239 796.3 0.6 2.4e-239 796.1 0.4 1.0 1 0 0 1 1 1 1 Utp8 family SYF2 PF08231.7 AAS53679.1 - 1.1e-08 35.3 7.2 1.1e-08 35.3 5.0 2.5 2 1 0 2 2 2 1 SYF2 splicing factor BAR_2 PF10455.4 AAS53680.1 - 2.1e-108 361.6 9.8 2.1e-108 361.6 6.8 1.5 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4197 PF13852.1 AAS53680.1 - 0.0011 18.5 0.3 0.0037 16.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4197) DUF3597 PF12200.3 AAS53680.1 - 0.01 16.2 0.3 0.01 16.2 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3597) Fea1 PF07692.6 AAS53680.1 - 0.021 13.6 0.1 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein V_ATPase_I PF01496.14 AAS53681.2 - 0.87 7.3 18.4 1.4 6.6 12.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 AAS53681.2 - 1.1 8.4 13.2 4.4 6.3 0.7 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 AAS53681.2 - 1.7 8.4 18.7 1.4 8.7 0.3 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ACCA PF03255.9 AAS53681.2 - 6.8 6.2 17.5 1.1 8.8 0.6 3.9 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Acyl-CoA_dh_2 PF08028.6 AAS53681.2 - 7.1 6.8 12.6 13 6.0 2.0 3.2 1 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain CENP-Q PF13094.1 AAS53681.2 - 7.6 6.5 41.7 0.18 11.7 13.3 3.8 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-TFIIIC PF12660.2 AAS53682.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.5 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex MARVEL PF01284.18 AAS53683.1 - 4.4e-29 101.1 13.0 5.5e-29 100.8 9.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Band_7 PF01145.20 AAS53684.1 - 6.8e-25 88.0 4.9 8.6e-25 87.6 3.0 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 AAS53684.1 - 0.026 13.9 1.7 0.034 13.5 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) UQ_con PF00179.21 AAS53685.1 - 1.5e-36 124.8 0.0 1.7e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 AAS53685.1 - 0.0022 17.6 0.1 0.0035 17.0 0.1 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 AAS53685.1 - 0.05 13.5 0.1 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain Pet20 PF08692.5 AAS53686.1 - 1e-10 41.6 0.0 1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet20 WW PF00397.21 AAS53688.1 - 5.5e-10 38.9 4.1 1.4e-09 37.6 2.8 1.7 1 0 0 1 1 1 1 WW domain FF PF01846.14 AAS53688.1 - 0.00017 21.4 2.4 0.00049 20.0 0.1 3.1 4 0 0 4 4 4 1 FF domain Proteasome PF00227.21 AAS53689.1 - 7.4e-59 198.2 0.3 9.4e-59 197.8 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AAS53689.1 - 1.3e-13 49.9 0.1 4.1e-13 48.3 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RuvA_C PF07499.8 AAS53689.1 - 0.012 15.7 0.0 0.065 13.4 0.0 2.3 2 0 0 2 2 2 0 RuvA, C-terminal domain Tmemb_170 PF10190.4 AAS53690.1 - 0.001 19.1 5.2 0.0014 18.6 3.6 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 SH3_1 PF00018.23 AAS53691.1 - 2e-16 59.0 0.0 3e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AAS53691.1 - 1.9e-12 46.5 0.0 3.8e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AAS53691.1 - 2.3e-12 46.1 0.0 3.3e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2680 PF10925.3 AAS53691.1 - 0.049 13.4 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) RP-C PF03428.8 AAS53691.1 - 0.1 12.0 0.1 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF605 PF04652.11 AAS53691.1 - 2.4 7.4 22.6 3.6 6.8 15.6 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 AAS53691.1 - 3.3 5.8 19.2 3.8 5.6 13.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NCA2 PF08637.5 AAS53692.1 - 1.1e-106 355.9 0.1 1.6e-106 355.4 0.1 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 MFS_1 PF07690.11 AAS53693.1 - 2.6e-35 121.7 29.9 2.6e-35 121.7 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AAS53693.1 - 1.1e-14 53.8 23.1 1.6e-14 53.3 16.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter GCR1_C PF12550.3 AAS53694.1 - 1.5e-20 72.7 0.0 3.5e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF946 PF06101.6 AAS53695.1 - 1.8e-08 32.8 0.9 3.9e-08 31.7 0.6 1.6 1 1 0 1 1 1 1 Plant protein of unknown function (DUF946) ABC2_membrane PF01061.19 AAS53697.2 - 5.1e-45 153.2 49.6 9.5e-26 90.2 11.5 2.5 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 AAS53697.2 - 1e-22 79.7 3.7 1.7e-19 69.4 0.2 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 AAS53697.2 - 5.2e-22 78.6 0.0 4.8e-10 39.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 AAS53697.2 - 7.6e-08 31.7 36.8 7.4e-05 21.9 10.3 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 AAS53697.2 - 0.0077 16.2 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 AAS53697.2 - 0.034 13.9 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.18 AAS53697.2 - 0.11 12.5 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 AAS53697.2 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SART-1 PF03343.8 AAS53698.1 - 6.8e-48 163.4 28.6 1.3e-46 159.2 19.8 2.1 1 1 0 1 1 1 1 SART-1 family Nop PF01798.13 AAS53699.2 - 2e-60 202.4 1.0 1.3e-59 199.7 1.1 2.2 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 AAS53699.2 - 3.1e-26 90.9 0.0 6e-26 90.0 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 AAS53699.2 - 4.4e-18 65.2 3.4 4.4e-18 65.2 2.3 2.9 2 1 1 3 3 3 1 NOP5NT (NUC127) domain CTP_transf_1 PF01148.15 AAS53700.1 - 1.5e-23 83.8 8.5 5.2e-21 75.4 3.3 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family Ribosomal_L18ae PF01775.12 AAS53701.3 - 1.8e-57 192.6 1.0 2.3e-57 192.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Sld5 PF05916.6 AAS53703.2 - 6.5e-13 48.9 0.1 1.3e-12 48.0 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein MFS_1 PF07690.11 AAS53704.1 - 2.4e-29 102.1 21.0 4e-29 101.4 14.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AAS53704.1 - 1.1e-24 86.8 20.6 6.6e-24 84.2 14.2 1.9 1 1 1 2 2 2 1 Sugar (and other) transporter Transgly_assoc PF04226.8 AAS53704.1 - 0.81 9.8 8.9 5.3 7.1 2.6 3.1 2 0 0 2 2 2 0 Transglycosylase associated protein Peptidase_M16_C PF05193.16 AAS53705.1 - 4.7e-19 68.7 0.0 1.8e-15 57.0 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AAS53705.1 - 1.7e-08 34.3 0.0 5e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Pkinase PF00069.20 AAS53706.1 - 3.5e-64 216.4 0.1 4.9e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53706.1 - 8.8e-33 113.4 0.0 1.4e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS53706.1 - 1e-07 31.2 0.0 1.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AAS53706.1 - 3.8e-06 26.1 0.0 7.1e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 AAS53706.1 - 0.048 12.5 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 AAS53706.1 - 0.065 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M4 PF01447.13 AAS53707.1 - 0.22 11.6 1.3 0.47 10.5 0.1 1.8 2 0 0 2 2 2 0 Thermolysin metallopeptidase, catalytic domain HlyIII PF03006.15 AAS53708.1 - 1.3e-51 175.1 17.3 1.6e-51 174.9 12.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related Fe_dep_repr_C PF02742.10 AAS53708.1 - 0.099 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain PTS_2-RNA PF01885.11 AAS53710.1 - 7.3e-55 185.1 0.0 9.5e-55 184.7 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 AAS53710.1 - 0.0049 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 La domain OapA PF04225.7 AAS53710.1 - 0.018 14.9 0.0 0.052 13.4 0.0 1.9 1 1 0 1 1 1 0 Opacity-associated protein A LysM-like domain Vps39_2 PF10367.4 AAS53712.1 - 0.0055 16.8 1.1 0.012 15.8 0.1 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CPL PF08144.6 AAS53713.1 - 5.2e-17 62.0 0.1 2.9e-14 53.1 0.0 3.2 3 0 0 3 3 3 2 CPL (NUC119) domain PUF PF00806.14 AAS53713.1 - 1.1e-07 30.8 3.7 10 5.8 0.0 7.0 7 0 0 7 7 7 3 Pumilio-family RNA binding repeat DUF4253 PF14062.1 AAS53713.1 - 0.039 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) DUF2890 PF11081.3 AAS53713.1 - 0.18 11.8 7.7 1 9.4 5.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Daxx PF03344.10 AAS53713.1 - 0.35 9.3 11.9 0.53 8.6 8.3 1.2 1 0 0 1 1 1 0 Daxx Family Sugar_tr PF00083.19 AAS53714.1 - 1.1e-129 432.9 30.8 1.3e-129 432.7 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AAS53714.1 - 4.6e-31 107.8 54.1 1.1e-27 96.6 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 AAS53714.1 - 0.0011 17.1 0.7 0.0011 17.1 0.5 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector TMEM237 PF15383.1 AAS53714.1 - 0.42 9.6 2.8 0.45 9.6 0.1 2.3 3 0 0 3 3 3 0 Transmembrane protein 237 Sec20 PF03908.8 AAS53715.1 - 4.7e-22 77.4 0.1 7.7e-22 76.8 0.1 1.3 1 0 0 1 1 1 1 Sec20 ERG4_ERG24 PF01222.12 AAS53717.2 - 2.1e-166 553.7 10.1 2.4e-166 553.5 7.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 AAS53717.2 - 1.7e-05 24.2 0.7 3.9e-05 23.0 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Aha1_N PF09229.6 AAS53718.1 - 1.2e-31 109.3 0.0 1.4e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal RNase_P_pop3 PF08228.6 AAS53719.1 - 6.1e-66 221.1 0.0 7.2e-66 220.8 0.0 1.0 1 0 0 1 1 1 1 RNase P subunit Pop3 WSC PF01822.14 AAS53720.1 - 2.4e-06 27.3 7.1 2.4e-06 27.3 4.9 2.6 2 0 0 2 2 2 1 WSC domain DUF4448 PF14610.1 AAS53720.1 - 0.0096 15.4 0.8 0.031 13.7 0.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4448) DUF912 PF06024.7 AAS53720.1 - 0.12 12.4 2.1 6.9 6.7 0.0 3.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TFIIA PF03153.8 AAS53720.1 - 0.33 10.8 13.9 0.45 10.3 9.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Opi1 PF08618.5 AAS53721.2 - 0.14 11.0 0.1 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 Vps55 PF04133.9 AAS53722.1 - 2.3e-44 149.9 3.4 2.7e-44 149.7 2.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2108 PF09881.4 AAS53722.1 - 0.043 13.6 0.1 0.043 13.6 0.1 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2108) HSP70 PF00012.15 AAS53723.2 - 7.1e-265 879.6 15.6 8.1e-265 879.4 10.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AAS53723.2 - 9.3e-15 54.0 3.3 1.5e-12 46.8 0.9 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 AAS53723.2 - 0.00028 20.5 0.0 0.00097 18.8 0.0 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 AAS53723.2 - 0.0011 18.7 11.2 0.13 12.0 0.5 4.7 3 3 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.13 AAS53723.2 - 0.014 14.4 5.3 0.35 9.9 0.1 3.4 3 1 0 3 3 3 0 Hydantoinase/oxoprolinase Gp-FAR-1 PF05823.7 AAS53723.2 - 0.022 14.7 7.0 0.053 13.4 4.9 1.6 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DnaG_DnaB_bind PF08278.6 AAS53723.2 - 6 7.0 7.9 5.1 7.3 2.4 2.9 3 2 0 3 3 3 0 DNA primase DnaG DnaB-binding CDT1 PF08839.6 AAS53724.2 - 0.094 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA replication factor CDT1 like Hydrolase PF00702.21 AAS53725.1 - 1.8e-24 87.3 0.0 9.9e-24 84.9 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AAS53725.1 - 3e-22 79.7 0.0 5.6e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 AAS53725.1 - 9.2e-17 60.8 0.1 2.7e-16 59.3 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 AAS53725.1 - 1.3e-06 28.2 0.0 2.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AAS53725.1 - 0.00092 18.8 0.1 0.0058 16.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AAS53725.1 - 0.041 13.1 0.0 0.092 12.0 0.0 1.5 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase MCM PF00493.18 AAS53726.2 - 3.7e-128 426.9 0.2 5.1e-128 426.5 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AAS53726.2 - 6.1e-19 68.6 0.0 1.5e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 AAS53726.2 - 9.6e-08 31.4 0.4 1.6e-06 27.4 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AAS53726.2 - 0.0035 16.9 0.0 0.0065 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AAS53726.2 - 0.0054 16.2 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain eIF-5a PF01287.15 AAS53727.1 - 7.5e-28 96.2 0.6 1.1e-27 95.7 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 AAS53727.1 - 0.00027 20.5 0.5 0.00052 19.6 0.4 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 AAS53727.1 - 0.0062 16.3 0.0 0.0099 15.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain TcdB_toxin_midN PF12256.3 AAS53727.1 - 0.078 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region Anp1 PF03452.9 AAS53728.1 - 7.4e-121 402.4 0.0 1e-120 401.9 0.0 1.1 1 0 0 1 1 1 1 Anp1 UBA PF00627.26 AAS53729.1 - 4.6e-21 74.0 1.7 2.4e-13 49.4 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 AAS53729.1 - 6.7e-14 51.0 0.1 4.3e-13 48.4 0.1 2.2 3 0 0 3 3 3 1 Ubiquitin family XPC-binding PF09280.6 AAS53729.1 - 7.8e-13 47.6 0.2 1.5e-12 46.7 0.2 1.4 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 AAS53729.1 - 1.8e-07 30.7 0.5 4.7e-07 29.4 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AAS53729.1 - 0.00013 22.0 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 AAS53729.1 - 0.00044 20.1 0.0 0.001 18.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 AAS53729.1 - 0.027 13.9 1.6 1.2 8.6 0.0 3.7 4 1 0 4 4 4 0 CUE domain HAD_2 PF13419.1 AAS53730.1 - 2.9e-20 73.2 0.0 3.7e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AAS53730.1 - 0.016 15.5 0.0 0.02 15.3 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cytochrom_C PF00034.16 AAS53731.1 - 1.1e-07 32.5 0.3 2.7e-07 31.3 0.2 1.6 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 AAS53731.1 - 7.2e-07 29.2 2.0 7.6e-06 26.0 1.4 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 AAS53731.1 - 0.04 13.3 0.2 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c-550 domain NAD_kinase PF01513.16 AAS53732.2 - 2.2e-76 256.3 0.0 3.9e-76 255.5 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase Transaldolase PF00923.14 AAS53732.2 - 0.075 12.1 0.2 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Transaldolase GDA1_CD39 PF01150.12 AAS53733.1 - 1.2e-107 360.1 0.0 1.4e-107 359.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 AAS53733.1 - 0.024 13.8 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Isy1 PF06246.7 AAS53734.1 - 6.3e-64 215.8 14.4 1.4e-62 211.4 10.0 2.0 1 1 0 1 1 1 1 Isy1-like splicing family DivIC PF04977.10 AAS53734.1 - 0.0035 16.7 7.7 0.33 10.4 3.3 2.5 2 0 0 2 2 2 2 Septum formation initiator eIF3_subunit PF08597.5 AAS53734.1 - 0.11 12.1 2.5 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF3801 PF12687.2 AAS53734.1 - 0.21 11.1 2.9 0.31 10.5 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Reo_sigmaC PF04582.7 AAS53735.1 - 0.046 12.8 8.5 0.022 13.9 0.9 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 AAS53735.1 - 0.63 7.6 24.7 0.051 11.2 13.3 1.7 1 1 0 2 2 2 0 Myosin tail DivIVA PF05103.8 AAS53735.1 - 0.79 9.7 16.0 0.088 12.8 2.2 2.8 1 1 1 3 3 3 0 DivIVA protein Prefoldin PF02996.12 AAS53735.1 - 1.7 8.3 8.9 1 9.0 0.2 3.1 3 1 0 3 3 3 0 Prefoldin subunit DUF3847 PF12958.2 AAS53735.1 - 2.4 7.9 12.2 0.7 9.6 2.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) IncA PF04156.9 AAS53735.1 - 4.5 6.8 21.6 2.1 7.8 8.0 2.7 1 1 1 2 2 2 0 IncA protein NPV_P10 PF05531.7 AAS53735.1 - 9 6.6 11.6 0.079 13.2 0.3 3.2 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein YL1_C PF08265.6 AAS53736.1 - 2.4e-15 55.7 0.7 4.9e-15 54.7 0.1 1.7 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Beta_elim_lyase PF01212.16 AAS53737.2 - 1.3e-78 264.0 0.0 1.6e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 AAS53737.2 - 4.1e-06 25.9 0.0 5.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II FAD_binding_2 PF00890.19 AAS53738.1 - 2e-81 273.9 2.3 2.3e-81 273.7 1.6 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 AAS53738.1 - 4.5e-08 32.3 1.2 6.9e-05 21.9 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AAS53738.1 - 2.1e-07 31.0 0.2 2.9e-05 24.0 0.2 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AAS53738.1 - 1.9e-05 24.6 0.7 0.00014 21.8 0.4 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AAS53738.1 - 4.4e-05 23.6 0.2 0.00035 20.7 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AAS53738.1 - 5.3e-05 22.2 2.7 0.0011 17.9 0.7 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 AAS53738.1 - 0.00011 21.4 4.0 0.0046 16.0 0.6 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 AAS53738.1 - 0.00056 19.0 1.3 0.0015 17.6 0.9 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 AAS53738.1 - 0.012 15.4 0.6 4.4 7.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 AAS53738.1 - 0.014 14.5 2.5 0.025 13.6 1.7 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 AAS53738.1 - 0.15 11.7 0.2 0.25 10.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 AAS53738.1 - 0.61 8.4 9.4 0.59 8.5 1.4 2.9 3 0 0 3 3 3 0 HI0933-like protein SUR7 PF06687.7 AAS53739.1 - 5.2e-36 124.2 9.5 6.1e-36 123.9 6.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 AAS53739.1 - 7 6.4 11.4 1.6 8.6 5.5 1.6 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Thymidylate_kin PF02223.12 AAS53740.1 - 3.5e-39 134.1 0.0 4.2e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 AAS53740.1 - 1e-05 25.5 0.5 1.6e-05 24.9 0.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AAS53740.1 - 0.003 17.4 0.0 0.007 16.2 0.0 1.7 1 1 1 2 2 2 1 AAA domain CPT PF07931.7 AAS53740.1 - 0.015 14.9 0.0 0.037 13.6 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein FAD_binding_4 PF01565.18 AAS53740.1 - 0.057 12.8 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain AAA_17 PF13207.1 AAS53740.1 - 0.15 12.8 0.0 0.24 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Clat_adaptor_s PF01217.15 AAS53741.1 - 1.9e-48 163.8 0.3 2.1e-48 163.6 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AAA PF00004.24 AAS53742.2 - 7.7e-54 181.4 0.0 3.3e-43 147.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 AAS53742.2 - 2.7e-25 88.2 0.1 7.4e-25 86.8 0.0 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 AAS53742.2 - 1.2e-13 51.5 2.4 2.2e-06 27.7 0.0 4.8 3 2 2 6 6 5 2 AAA ATPase domain AAA_22 PF13401.1 AAS53742.2 - 3.6e-09 36.8 0.4 0.0062 16.6 0.0 4.1 3 2 1 4 4 3 2 AAA domain NACHT PF05729.7 AAS53742.2 - 2.1e-07 30.7 0.1 0.011 15.4 0.0 3.6 4 0 0 4 4 4 2 NACHT domain IstB_IS21 PF01695.12 AAS53742.2 - 7.3e-07 28.7 0.0 0.012 15.0 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 AAS53742.2 - 1.3e-06 28.3 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 AAS53742.2 - 1.5e-06 28.2 0.0 0.00085 19.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 AAS53742.2 - 4e-06 26.7 0.0 0.0058 16.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AAS53742.2 - 7.9e-06 26.6 0.0 0.054 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 AAS53742.2 - 2.8e-05 23.8 0.0 0.037 13.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 AAS53742.2 - 5.7e-05 22.5 0.4 0.57 9.5 0.1 4.2 3 1 0 4 4 4 1 AAA domain Arch_ATPase PF01637.13 AAS53742.2 - 7.3e-05 22.5 0.0 0.094 12.3 0.0 3.1 2 1 1 3 3 3 1 Archaeal ATPase AAA_24 PF13479.1 AAS53742.2 - 8.1e-05 22.3 0.0 0.13 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 AAS53742.2 - 0.00011 21.3 0.1 0.0021 17.1 0.0 2.7 2 1 1 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 AAS53742.2 - 0.00074 19.5 0.0 0.21 11.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 AAS53742.2 - 0.0011 19.1 0.0 0.59 10.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 AAS53742.2 - 0.0013 17.9 0.1 0.13 11.3 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 AAS53742.2 - 0.0016 18.7 0.0 0.82 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 AAS53742.2 - 0.0043 17.3 0.0 8.1 6.7 0.0 3.2 2 1 1 3 3 3 0 ABC transporter NB-ARC PF00931.17 AAS53742.2 - 0.0089 14.9 0.0 1.7 7.4 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.7 AAS53742.2 - 0.017 14.2 0.0 0.085 11.9 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.21 AAS53742.2 - 0.019 14.4 0.1 8.7 5.7 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 AAS53742.2 - 0.033 13.6 0.0 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.8 AAS53742.2 - 0.04 12.6 0.0 0.082 11.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Bac_DnaA PF00308.13 AAS53742.2 - 0.048 13.2 0.0 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein DUF258 PF03193.11 AAS53742.2 - 0.058 12.5 0.1 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Cytidylate_kin2 PF13189.1 AAS53742.2 - 0.084 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_3 PF07726.6 AAS53742.2 - 0.12 12.0 0.0 0.34 10.5 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_35 PF14516.1 AAS53742.2 - 0.16 10.5 0.0 1.9 7.0 0.0 2.4 2 1 1 3 3 3 0 AAA-like domain Torsin PF06309.6 AAS53742.2 - 0.2 11.5 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Torsin AAA_23 PF13476.1 AAS53742.2 - 0.23 11.7 0.0 12 6.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 AAS53743.1 - 1.7e-40 138.8 0.0 2.5e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53743.1 - 3.4e-11 42.7 0.0 7.1e-11 41.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS53743.1 - 0.00028 19.9 0.0 0.00078 18.4 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 AAS53743.1 - 0.00098 18.2 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mito_carr PF00153.22 AAS53744.1 - 6.7e-10 38.5 0.0 0.0028 17.3 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Dpy-30 PF05186.8 AAS53745.1 - 3.2e-14 52.1 0.0 4e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Dpy-30 motif SNARE PF05739.14 AAS53746.1 - 2.4e-10 39.9 1.5 2.4e-10 39.9 1.0 1.8 2 0 0 2 2 2 1 SNARE domain Atg14 PF10186.4 AAS53746.1 - 0.012 14.6 1.1 0.019 13.9 0.8 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin-6_N PF09177.6 AAS53746.1 - 0.018 15.4 5.5 0.11 12.9 1.1 3.0 2 2 0 2 2 2 0 Syntaxin 6, N-terminal DUF3376 PF11856.3 AAS53746.1 - 0.057 12.7 7.2 0.069 12.5 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) Sec20 PF03908.8 AAS53746.1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Sec20 PilJ PF13675.1 AAS53746.1 - 2.2 8.6 12.4 4.4 7.6 1.8 2.3 1 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DAO PF01266.19 AAS53747.1 - 3.9e-71 239.8 0.0 6.4e-71 239.1 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AAS53747.1 - 4.2e-07 29.9 0.1 1.1e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AAS53747.1 - 0.00052 19.1 0.2 0.00091 18.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 AAS53747.1 - 0.0026 17.5 0.2 0.0061 16.3 0.1 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Strep_67kDa_ant PF06100.6 AAS53747.1 - 0.0049 15.2 0.3 0.0074 14.6 0.2 1.2 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family Pyr_redox PF00070.22 AAS53747.1 - 0.013 15.8 0.3 0.033 14.5 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 AAS53747.1 - 0.014 14.0 0.3 0.023 13.3 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 AAS53747.1 - 0.017 15.1 0.0 0.59 10.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 AAS53747.1 - 0.017 14.1 0.2 0.025 13.5 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Pkinase PF00069.20 AAS53748.1 - 4e-69 232.6 0.0 6.3e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS53748.1 - 1e-33 116.5 0.0 1.5e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS53748.1 - 4.4e-11 42.2 0.0 7e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AAS53748.1 - 0.00052 19.1 0.0 0.00091 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AAS53748.1 - 0.00088 19.0 0.0 0.018 14.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 AAS53748.1 - 0.0088 15.4 0.1 0.066 12.5 0.0 2.3 2 1 0 3 3 3 1 RIO1 family Gsf2 PF11055.3 AAS53752.1 - 3.8e-180 598.3 0.1 4.5e-180 598.1 0.1 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 Baculo_PEP_N PF04512.7 AAS53752.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus CPSF_A PF03178.10 AAS53753.2 - 1.2e-57 195.3 0.0 8.5e-56 189.3 0.0 3.4 3 1 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 AAS53753.2 - 2.3e-25 88.7 0.0 8.7e-25 86.8 0.0 2.0 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Suc_Fer-like PF06999.7 AAS53754.1 - 1.9e-26 93.5 0.0 2.9e-26 92.9 0.0 1.3 1 1 0 1 1 1 1 Sucrase/ferredoxin-like zf-HIT PF04438.11 AAS53755.1 - 2.2e-10 39.9 13.4 3.8e-10 39.2 9.3 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF1610 PF07754.6 AAS53755.1 - 0.0022 18.0 5.0 0.0046 17.0 3.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1610) zf-Mss51 PF13824.1 AAS53755.1 - 0.02 14.7 6.1 0.051 13.4 4.2 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 AAS53755.1 - 0.11 12.3 11.7 0.19 11.6 8.1 1.4 1 0 0 1 1 1 0 MYND finger VP_N-CPKC PF11475.3 AAS53755.1 - 0.74 9.4 4.8 1.8 8.1 3.3 1.7 1 0 0 1 1 1 0 Virion protein N terminal domain Sedlin_N PF04628.8 AAS53756.1 - 2e-07 30.9 0.0 2.6e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF676 PF05057.9 AAS53757.1 - 7.1e-43 146.4 0.0 1.2e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 AAS53757.1 - 0.00049 19.7 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 AAS53757.1 - 0.0012 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AAS53757.1 - 0.025 14.4 0.0 0.057 13.2 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 AAS53757.1 - 0.034 13.7 0.0 0.083 12.4 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) TraP PF07296.6 AAS53757.1 - 0.057 12.3 0.1 0.092 11.6 0.1 1.3 1 0 0 1 1 1 0 TraP protein Cutinase PF01083.17 AAS53757.1 - 0.071 12.8 0.1 0.17 11.6 0.1 1.8 1 1 0 1 1 1 0 Cutinase TPK_catalytic PF04263.11 AAS53758.1 - 7e-17 61.1 0.1 9.4e-16 57.5 0.0 2.2 1 1 1 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 AAS53758.1 - 9.5e-09 34.8 0.0 2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TFIID-18kDa PF02269.11 AAS53759.1 - 1e-35 121.4 0.3 1.1e-34 118.1 0.1 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Ribosomal_60s PF00428.14 AAS53759.1 - 0.00092 19.5 2.4 0.00092 19.5 1.6 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF3564 PF12087.3 AAS53759.1 - 0.058 12.9 0.0 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3564) AAA PF00004.24 AAS53760.2 - 6.2e-06 26.4 0.1 0.00039 20.6 0.0 3.2 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 AAS53760.2 - 0.033 14.5 0.3 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain KH_1 PF00013.24 AAS53761.2 - 0.00037 20.0 0.4 0.00077 19.0 0.3 1.5 1 0 0 1 1 1 1 KH domain MDM31_MDM32 PF08118.6 AAS53762.1 - 5e-73 246.2 8.6 8e-35 120.2 0.1 4.0 2 1 2 4 4 4 4 Yeast mitochondrial distribution and morphology (MDM) proteins G-patch_2 PF12656.2 AAS53763.1 - 4.8e-21 74.3 0.2 4.8e-21 74.3 0.1 2.1 2 0 0 2 2 2 1 DExH-box splicing factor binding site She9_MDM33 PF05546.6 AAS53764.1 - 6.7e-93 310.0 12.9 6.7e-93 310.0 9.0 2.0 2 0 0 2 2 2 1 She9 / Mdm33 family PsbH PF00737.15 AAS53764.1 - 0.06 12.9 0.3 0.11 12.0 0.2 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Phi-29_GP16_7 PF06720.6 AAS53764.1 - 0.2 11.3 4.1 0.073 12.7 0.4 2.1 2 1 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 PspA_IM30 PF04012.7 AAS53764.1 - 0.31 10.3 20.6 2 7.7 1.2 3.0 2 1 0 2 2 2 0 PspA/IM30 family DUF1395 PF07160.7 AAS53764.1 - 0.45 9.9 15.9 0.016 14.6 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) Tropomyosin_1 PF12718.2 AAS53764.1 - 0.76 9.6 25.1 0.026 14.3 4.0 3.3 1 1 2 3 3 3 0 Tropomyosin like TMF_DNA_bd PF12329.3 AAS53764.1 - 5.3 6.9 25.4 0.14 11.9 1.0 4.4 2 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding AAA PF00004.24 AAS53765.2 - 3.3e-46 156.7 0.0 9e-46 155.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 AAS53765.2 - 2.8e-08 33.8 0.0 5.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 AAS53765.2 - 7.3e-08 32.2 0.1 3e-07 30.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AAS53765.2 - 5.5e-07 29.7 0.0 1.8e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AAS53765.2 - 1.3e-06 28.6 0.4 9.8e-05 22.4 0.3 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 AAS53765.2 - 7e-05 21.8 0.0 0.00012 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 AAS53765.2 - 0.00021 22.0 0.0 0.00077 20.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 AAS53765.2 - 0.00036 20.4 0.0 0.0009 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AAS53765.2 - 0.00042 19.4 0.0 0.00096 18.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 AAS53765.2 - 0.0013 18.5 0.0 0.0034 17.1 0.0 1.8 1 0 0 1 1 1 1 NTPase AAA_19 PF13245.1 AAS53765.2 - 0.0016 18.1 0.1 0.0039 16.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 AAS53765.2 - 0.0019 18.3 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 AAS53765.2 - 0.0021 17.1 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 AAS53765.2 - 0.0031 17.1 0.0 0.0084 15.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 AAS53765.2 - 0.0033 16.2 0.0 0.0053 15.5 0.0 1.4 1 1 0 1 1 1 1 TIP49 C-terminus AAA_11 PF13086.1 AAS53765.2 - 0.0035 16.9 0.0 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 AAS53765.2 - 0.004 16.7 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AAS53765.2 - 0.0042 16.9 0.0 0.0086 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AAS53765.2 - 0.0048 16.8 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 AAS53765.2 - 0.0049 16.3 0.0 0.17 11.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 AAS53765.2 - 0.0054 16.1 0.9 0.12 11.7 0.1 2.3 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 AAS53765.2 - 0.0054 16.4 0.1 0.068 12.8 0.0 2.3 1 1 0 2 2 2 1 NACHT domain AAA_30 PF13604.1 AAS53765.2 - 0.0054 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 AAS53765.2 - 0.0069 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 AAS53765.2 - 0.0071 15.5 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 AAS53765.2 - 0.016 14.9 0.3 0.17 11.5 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase IstB_IS21 PF01695.12 AAS53765.2 - 0.016 14.6 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 AAS53765.2 - 0.027 14.7 0.0 0.075 13.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 AAS53765.2 - 0.035 14.4 0.1 2.9 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 AAS53765.2 - 0.081 12.5 0.0 0.19 11.3 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein NB-ARC PF00931.17 AAS53765.2 - 0.082 11.7 0.0 0.27 10.0 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Glyco_transf_22 PF03901.12 AAS53766.2 - 2.5e-70 237.5 13.7 3e-70 237.3 9.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family IBN_N PF03810.14 AAS53767.1 - 5.1e-12 45.5 0.8 1.5e-11 43.9 0.2 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Telomerase_RBD PF12009.3 AAS53767.1 - 0.0021 17.9 0.4 0.0061 16.4 0.3 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain Vac14_Fab1_bd PF12755.2 AAS53767.1 - 0.0074 16.6 1.8 0.027 14.8 0.1 2.9 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region CBFD_NFYB_HMF PF00808.18 AAS53768.1 - 5.1e-14 52.0 1.5 7.9e-14 51.4 1.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hydrolase_like PF13242.1 AAS53768.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Utp12 PF04003.7 AAS53769.2 - 2.2e-22 79.0 1.8 3.6e-22 78.3 1.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family TFIIA PF03153.8 AAS53769.2 - 0.35 10.7 10.6 0.71 9.7 7.3 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IU_nuc_hydro PF01156.14 AAS53770.1 - 1.2e-77 261.2 0.0 1.3e-77 261.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase p450 PF00067.17 AAS53771.1 - 1.4e-49 168.8 0.0 1.8e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cyclin_N PF00134.18 AAS53771.1 - 0.099 12.2 0.2 0.29 10.6 0.0 1.8 2 1 0 2 2 2 0 Cyclin, N-terminal domain DIT1_PvcA PF05141.7 AAS53772.1 - 8.5e-105 350.0 0.0 1.3e-104 349.4 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein SHS2_Rpb7-N PF03876.12 AAS53773.1 - 8.8e-18 64.1 0.0 1.4e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 AAS53773.1 - 1.7e-11 44.0 0.0 2.7e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 AAS53773.1 - 0.00015 21.9 0.0 0.00031 20.9 0.0 1.5 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 Ribosomal_L13 PF00572.13 AAS53774.1 - 8.7e-46 155.1 0.1 1e-45 154.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 RNA_pol_Rpb2_6 PF00562.23 AAS53775.1 - 3.4e-125 417.7 0.3 5.5e-125 417.1 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AAS53775.1 - 5.6e-68 227.8 0.1 9.2e-68 227.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 AAS53775.1 - 9.6e-52 175.1 0.1 1.8e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 AAS53775.1 - 9.5e-31 105.9 0.1 2.3e-30 104.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 AAS53775.1 - 1.6e-27 95.0 0.8 3.5e-27 93.9 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 AAS53775.1 - 6e-22 77.1 0.1 1.8e-21 75.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 AAS53775.1 - 2.8e-18 65.6 0.7 6.9e-18 64.3 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_L23 PF00276.15 AAS53776.1 - 2.2e-21 75.6 0.0 3.5e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 DUF2250 PF10007.4 AAS53776.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) TRAPP PF04051.11 AAS53779.1 - 5.7e-45 152.5 0.0 6.9e-45 152.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Acetyltransf_1 PF00583.19 AAS53780.2 - 3.3e-16 59.0 0.1 5.2e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AAS53780.2 - 5.3e-07 29.3 0.0 8.9e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 AAS53780.2 - 6.3e-06 26.2 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AAS53780.2 - 2e-05 24.6 0.0 3.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AAS53780.2 - 0.0015 18.4 0.4 0.0032 17.3 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AAS53780.2 - 0.0015 18.7 0.0 0.0019 18.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 AAS53780.2 - 0.037 13.6 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AAS53780.2 - 0.068 13.0 0.2 0.14 12.0 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AAS53780.2 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase S-methyl_trans PF02574.11 AAS53781.2 - 3.9e-53 180.7 0.0 4.5e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Metallophos_2 PF12850.2 AAS53782.1 - 1.2e-14 54.4 0.0 1.7e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain tRNA-synt_2b PF00587.20 AAS53783.1 - 5.4e-22 78.1 0.0 3e-21 75.7 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 AAS53783.1 - 0.00046 20.1 0.2 0.00083 19.3 0.2 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain WEMBL PF05701.6 AAS53783.1 - 0.035 12.5 2.9 0.051 12.0 2.0 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Spectrin PF00435.16 AAS53783.1 - 0.37 11.0 2.2 3.5 7.9 1.4 2.3 2 1 0 2 2 2 0 Spectrin repeat Ribosomal_L27e PF01777.13 AAS53784.1 - 1.1e-35 121.5 4.2 1.5e-35 121.1 2.9 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 AAS53784.1 - 0.0015 18.1 1.7 0.0026 17.4 1.1 1.4 1 0 0 1 1 1 1 KOW motif Ndr PF03096.9 AAS53784.1 - 0.11 10.9 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 Ndr family HLH PF00010.21 AAS53785.2 - 2e-11 43.4 3.1 2e-11 43.4 2.2 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain YL1 PF05764.8 AAS53785.2 - 7e-05 22.5 10.2 0.0001 21.9 7.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein MRP-S31 PF15433.1 AAS53785.2 - 0.001 18.5 6.4 0.0019 17.7 4.4 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 Macoilin PF09726.4 AAS53785.2 - 0.0058 14.9 2.4 0.0063 14.8 1.6 1.2 1 0 0 1 1 1 1 Transmembrane protein UPF0175 PF03683.8 AAS53785.2 - 0.015 14.7 0.1 0.045 13.2 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) GrpE PF01025.14 AAS53785.2 - 0.026 14.0 3.9 0.059 12.9 2.7 1.6 1 0 0 1 1 1 0 GrpE SDA1 PF05285.7 AAS53785.2 - 0.043 13.1 17.5 0.051 12.8 12.1 1.2 1 0 0 1 1 1 0 SDA1 bZIP_1 PF00170.16 AAS53785.2 - 4.7 7.2 10.7 0.28 11.1 3.2 2.1 1 1 1 2 2 2 0 bZIP transcription factor CN_hydrolase PF00795.17 AAS53786.1 - 7e-11 41.8 0.0 1.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LicD PF04991.8 AAS53787.2 - 1.8e-50 171.9 1.2 1.8e-50 171.9 0.8 3.3 2 1 0 2 2 2 1 LicD family CAF-1_p150 PF11600.3 AAS53787.2 - 0.18 11.1 67.0 0.36 10.1 46.4 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 AAS53787.2 - 4 6.6 31.3 6.1 6.0 21.7 1.2 1 0 0 1 1 1 0 SprA-related family Hid1 PF12722.2 AAS53787.2 - 7.7 4.0 18.6 10 3.6 12.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIS_C PF01096.13 AAS53788.1 - 5.7e-18 64.2 2.1 5.7e-18 64.2 1.5 2.3 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 AAS53788.1 - 3.2e-09 36.3 3.9 9.2e-07 28.4 0.1 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zf-ribbon_3 PF13248.1 AAS53788.1 - 3.2e-05 22.9 2.5 1 8.6 0.0 3.6 3 0 0 3 3 3 1 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 AAS53788.1 - 0.00037 19.7 5.6 0.015 14.6 1.6 2.7 2 1 0 2 2 2 1 TFIIB zinc-binding zinc_ribbon_2 PF13240.1 AAS53788.1 - 0.00062 19.1 9.3 0.1 12.0 0.1 3.4 3 1 0 3 3 3 1 zinc-ribbon domain DZR PF12773.2 AAS53788.1 - 0.0016 18.1 6.3 0.95 9.3 0.1 3.0 2 1 1 3 3 3 2 Double zinc ribbon Lar_restr_allev PF14354.1 AAS53788.1 - 0.0024 18.1 0.4 0.0024 18.1 0.3 2.7 2 1 0 2 2 2 1 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 AAS53788.1 - 0.0069 16.1 4.8 0.017 14.9 0.6 2.4 2 1 0 2 2 2 1 Transposase zinc-ribbon domain Ogr_Delta PF04606.7 AAS53788.1 - 0.012 15.2 2.3 0.046 13.3 1.6 2.1 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Terminase_GpA PF05876.7 AAS53788.1 - 0.012 13.9 0.7 0.012 13.9 0.5 1.4 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) C1_1 PF00130.17 AAS53788.1 - 0.013 15.1 2.5 0.37 10.5 0.0 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Baculo_LEF5_C PF11792.3 AAS53788.1 - 0.023 14.0 1.4 0.023 14.0 0.9 2.5 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-TFIIB PF13453.1 AAS53788.1 - 0.041 13.0 1.1 0.12 11.6 0.8 1.8 1 0 0 1 1 1 0 Transcription factor zinc-finger DUF2387 PF09526.5 AAS53788.1 - 0.042 13.7 5.1 0.068 13.1 0.1 2.9 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Nudix_N_2 PF14803.1 AAS53788.1 - 0.046 13.4 7.0 6.1 6.6 0.0 3.3 3 0 0 3 3 3 0 Nudix N-terminal Rubredoxin PF00301.15 AAS53788.1 - 0.065 13.1 8.0 10 6.0 0.1 3.7 4 0 0 4 4 4 0 Rubredoxin RRN7 PF11781.3 AAS53788.1 - 0.067 12.6 7.4 7.1 6.2 0.3 4.2 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C3HC4_3 PF13920.1 AAS53788.1 - 0.074 12.7 2.6 3.3 7.4 0.1 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-CHY PF05495.7 AAS53788.1 - 0.098 12.8 3.2 3.7 7.7 0.4 2.5 2 0 0 2 2 2 0 CHY zinc finger DUF2072 PF09845.4 AAS53788.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.5 2 1 1 3 3 3 0 Zn-ribbon containing protein (DUF2072) ER-remodelling PF14755.1 AAS53788.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Intracellular membrane remodeller zf-C3HC4_4 PF15227.1 AAS53788.1 - 0.12 12.2 0.2 0.12 12.2 0.1 2.8 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING Elf1 PF05129.8 AAS53788.1 - 0.19 11.4 0.2 0.19 11.4 0.1 2.3 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C3HC4_2 PF13923.1 AAS53788.1 - 0.19 11.7 4.0 2.5 8.2 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.6 AAS53788.1 - 0.22 11.2 6.0 2.7 7.7 1.3 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-C4_Topoisom PF01396.14 AAS53788.1 - 0.33 10.4 6.6 0.086 12.3 0.9 2.6 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Zn-ribbon_8 PF09723.5 AAS53788.1 - 0.37 10.7 10.1 3.2 7.7 0.1 3.3 3 1 0 3 3 3 0 Zinc ribbon domain CpXC PF14353.1 AAS53788.1 - 0.53 10.2 4.8 3.2 7.7 0.1 2.8 1 1 2 3 3 3 0 CpXC protein YhfH PF14149.1 AAS53788.1 - 0.75 9.6 3.5 22 4.9 0.3 3.1 3 0 0 3 3 3 0 YhfH-like protein zf-ISL3 PF14690.1 AAS53788.1 - 1 9.4 3.9 3.1 7.9 0.1 2.8 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Prok-RING_1 PF14446.1 AAS53788.1 - 1.6 8.4 9.2 8.7 6.1 1.5 3.3 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 zinc_ribbon_4 PF13717.1 AAS53788.1 - 2.3 7.9 8.6 17 5.1 0.1 3.5 4 0 0 4 4 3 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 AAS53788.1 - 3 7.3 10.8 10 5.6 0.7 3.7 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit UPF0547 PF10571.4 AAS53788.1 - 4.1 7.1 12.9 0.92 9.2 0.2 3.5 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zinc_ribbon_5 PF13719.1 AAS53788.1 - 6.4 6.4 9.8 15 5.2 0.1 3.5 4 0 0 4 4 3 0 zinc-ribbon domain zf-HYPF PF07503.7 AAS53788.1 - 7.2 6.1 8.0 2.1 7.8 0.1 3.1 3 0 0 3 3 3 0 HypF finger Cpn60_TCP1 PF00118.19 AAS53789.1 - 7.2e-144 480.0 1.7 8.3e-144 479.8 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family YbjQ_1 PF01906.12 AAS53789.1 - 0.0052 17.1 0.2 2.7 8.4 0.0 3.1 3 0 0 3 3 3 2 Putative heavy-metal-binding CPT PF07931.7 AAS53789.1 - 0.018 14.6 0.4 7.2 6.1 0.0 3.0 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AP_endonuc_2 PF01261.19 AAS53789.1 - 0.056 12.7 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Actin PF00022.14 AAS53790.1 - 1.5e-92 310.0 0.0 4e-92 308.6 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AAS53790.1 - 1.2e-05 24.0 0.0 0.01 14.4 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FAT PF02259.18 AAS53791.2 - 1.4e-139 465.0 0.4 1.4e-139 465.0 0.3 2.8 4 0 0 4 4 4 1 FAT domain DUF3385 PF11865.3 AAS53791.2 - 5.7e-66 221.3 0.5 5.7e-66 221.3 0.3 4.9 6 0 0 6 6 6 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 AAS53791.2 - 5e-61 206.1 0.1 1.1e-60 205.0 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 AAS53791.2 - 1.3e-42 143.8 4.2 2.3e-42 143.1 0.3 3.3 3 0 0 3 3 3 1 Rapamycin binding domain FATC PF02260.15 AAS53791.2 - 4.8e-18 64.2 0.1 1.1e-17 63.1 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 AAS53791.2 - 3.6e-15 56.0 9.9 0.12 12.6 0.0 9.4 6 2 3 9 9 9 4 HEAT repeats HEAT_EZ PF13513.1 AAS53791.2 - 2.3e-09 37.4 3.2 0.0021 18.5 0.0 8.3 7 1 0 7 7 7 1 HEAT-like repeat HEAT PF02985.17 AAS53791.2 - 1.7e-06 27.6 11.1 0.059 13.4 0.0 7.9 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.2 AAS53791.2 - 0.00081 19.7 10.5 3 8.2 0.0 6.4 6 1 0 6 6 6 2 Vacuolar 14 Fab1-binding region Yae1_N PF09811.4 AAS53792.2 - 2.4e-15 55.7 0.3 3.5e-15 55.2 0.2 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal CutC PF03932.9 AAS53792.2 - 0.033 13.4 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 CutC family AAA PF00004.24 AAS53793.2 - 5.6e-16 58.9 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 AAS53793.2 - 9.2e-16 57.6 0.1 1.9e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 AAS53793.2 - 8.2e-15 54.8 0.1 2.7e-14 53.1 0.0 1.9 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.10 AAS53793.2 - 2.8e-10 39.4 0.0 6.7e-08 31.6 0.0 2.2 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 AAS53793.2 - 5.1e-06 25.7 0.0 1.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 AAS53793.2 - 5.6e-06 26.5 0.0 2.9e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AAS53793.2 - 1.7e-05 24.5 0.0 2.1e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AAS53793.2 - 2.9e-05 24.1 0.2 0.00094 19.2 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 AAS53793.2 - 0.00016 21.5 0.0 0.0004 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 AAS53793.2 - 0.0003 20.0 0.0 0.0071 15.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 AAS53793.2 - 0.00032 20.4 0.0 0.00064 19.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 AAS53793.2 - 0.0013 18.4 0.3 0.0029 17.2 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 AAS53793.2 - 0.0028 17.2 0.0 0.016 14.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 AAS53793.2 - 0.0032 17.8 0.1 0.012 15.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 AAS53793.2 - 0.0039 17.0 0.0 0.016 15.0 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 AAS53793.2 - 0.004 16.4 1.2 4.6 6.4 0.0 3.3 3 1 0 3 3 3 1 PhoH-like protein DUF815 PF05673.8 AAS53793.2 - 0.0087 15.0 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 AAS53793.2 - 0.012 15.3 0.1 0.27 10.9 0.0 2.6 1 1 2 3 3 3 0 Archaeal ATPase AAA_17 PF13207.1 AAS53793.2 - 0.013 16.3 0.0 0.036 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 AAS53793.2 - 0.015 13.9 0.1 1.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 AAS53793.2 - 0.016 14.9 0.0 0.061 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 AAS53793.2 - 0.022 13.7 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 AAS53793.2 - 0.042 14.1 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AAS53793.2 - 0.043 14.0 0.0 0.099 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 AAS53793.2 - 0.047 13.2 0.1 0.58 9.7 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 AAS53793.2 - 0.049 12.4 0.0 0.92 8.2 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain FtsK_SpoIIIE PF01580.13 AAS53793.2 - 0.066 12.6 0.0 0.19 11.1 0.0 1.8 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.1 AAS53793.2 - 0.085 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AAS53793.2 - 0.086 12.2 0.0 0.27 10.6 0.0 2.1 1 1 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 AAS53793.2 - 0.09 12.1 0.4 0.26 10.6 0.1 2.0 2 1 0 2 2 2 0 AAA domain Zip PF02535.17 AAS53794.2 - 1.3 7.9 8.6 3.7 6.4 0.3 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Xpo1 PF08389.7 AAS53795.2 - 3.7e-42 143.7 1.5 1.8e-41 141.5 0.0 2.8 3 0 0 3 3 3 1 Exportin 1-like protein ATP-gua_PtransN PF02807.10 AAS53795.2 - 0.017 15.2 0.0 0.061 13.4 0.0 1.9 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, N-terminal domain Ham1p_like PF01725.11 AAS53796.1 - 6.9e-50 169.0 0.0 7.8e-50 168.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family HEAT_2 PF13646.1 AAS53797.2 - 3.1e-35 120.3 1.5 7.2e-17 61.4 0.0 3.3 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 AAS53797.2 - 2e-17 61.7 13.0 0.0001 22.4 0.0 8.4 9 0 0 9 9 9 4 PBS lyase HEAT-like repeat HEAT PF02985.17 AAS53797.2 - 1.5e-14 52.7 1.6 0.001 18.9 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 AAS53797.2 - 3.5e-08 33.6 11.0 6.5e-05 23.2 0.2 5.8 5 2 2 7 7 7 2 HEAT-like repeat Arm PF00514.18 AAS53797.2 - 0.0013 18.5 0.4 1.1 9.2 0.0 3.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 AAS53797.2 - 0.13 11.6 0.3 4 6.7 0.0 2.8 2 1 1 3 3 3 0 CLASP N terminal RuvA_C PF07499.8 AAS53797.2 - 0.23 11.6 1.7 35 4.6 0.0 3.4 3 0 0 3 3 3 0 RuvA, C-terminal domain PAC2 PF09754.4 AAS53798.1 - 4e-37 128.1 0.0 4.7e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 PAC2 family ATP_bind_1 PF03029.12 AAS53799.2 - 1.3e-83 280.1 0.2 2.8e-83 279.1 0.0 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 AAS53799.2 - 3.9e-07 29.6 0.1 4.4e-06 26.2 0.1 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 AAS53799.2 - 4.2e-05 23.0 0.1 0.00024 20.5 0.0 2.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 AAS53799.2 - 6.4e-05 22.8 0.0 0.00018 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AAS53799.2 - 7.6e-05 23.5 0.3 0.00066 20.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AAS53799.2 - 0.00011 22.3 0.0 0.0005 20.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.13 AAS53799.2 - 0.00035 19.8 0.0 0.0083 15.4 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_10 PF12846.2 AAS53799.2 - 0.00037 20.0 1.5 0.0043 16.5 1.0 2.2 1 1 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 AAS53799.2 - 0.00038 20.4 0.1 0.0017 18.2 0.0 2.2 2 2 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 AAS53799.2 - 0.00086 18.8 0.0 0.009 15.5 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 AAS53799.2 - 0.0012 18.2 0.1 0.035 13.5 0.0 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain NACHT PF05729.7 AAS53799.2 - 0.0014 18.3 0.0 0.0034 17.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 AAS53799.2 - 0.0038 17.2 0.0 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 AAS53799.2 - 0.004 16.7 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arf PF00025.16 AAS53799.2 - 0.0044 16.2 0.0 0.51 9.5 0.0 2.6 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_18 PF13238.1 AAS53799.2 - 0.0066 16.7 0.1 0.031 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 AAS53799.2 - 0.014 14.1 0.0 2.3 6.8 0.0 2.3 2 0 0 2 2 2 0 ArgK protein Miro PF08477.8 AAS53799.2 - 0.017 15.5 0.5 6.7 7.2 0.0 2.7 3 0 0 3 3 2 0 Miro-like protein Thymidylate_kin PF02223.12 AAS53799.2 - 0.024 13.9 0.8 0.46 9.8 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase MobB PF03205.9 AAS53799.2 - 0.026 14.2 0.0 0.087 12.5 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 AAS53799.2 - 0.029 14.6 1.5 0.75 10.0 0.2 2.3 2 0 0 2 2 2 0 AAA domain Antigen_Bd37 PF11641.3 AAS53799.2 - 0.042 13.1 1.6 0.29 10.3 0.8 2.1 1 1 1 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein G-alpha PF00503.15 AAS53799.2 - 0.042 12.5 0.5 1.1 7.8 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit SRPRB PF09439.5 AAS53799.2 - 0.044 13.0 0.1 1 8.5 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit cobW PF02492.14 AAS53799.2 - 0.056 12.8 0.0 3 7.2 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 AAS53799.2 - 0.08 12.7 0.2 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 KTI12 PF08433.5 AAS53799.2 - 0.11 11.6 1.2 0.13 11.4 0.0 1.7 2 0 0 2 2 1 0 Chromatin associated protein KTI12 U1snRNP70_N PF12220.3 AAS53799.2 - 0.17 12.2 3.5 0.098 12.9 0.8 1.8 2 0 0 2 2 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF106 PF01956.11 AAS53800.1 - 1.4e-54 184.1 1.4 2e-54 183.6 1.0 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 DUF1237 PF06824.6 AAS53801.2 - 8.7e-183 607.7 0.0 1e-182 607.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) PEMT PF04191.8 AAS53802.1 - 5.6e-34 116.4 2.1 1.2e-33 115.3 1.4 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF4118 PF13493.1 AAS53802.1 - 0.03 14.5 0.1 0.03 14.5 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4118) TRI12 PF06609.8 AAS53802.1 - 0.038 12.2 0.3 0.048 11.8 0.2 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) ABC_membrane PF00664.18 AAS53803.1 - 1e-74 251.4 39.2 9.8e-39 133.4 10.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AAS53803.1 - 7.7e-62 207.6 0.0 4.7e-30 104.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 AAS53803.1 - 8.1e-20 70.9 4.7 5.1e-09 35.6 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AAS53803.1 - 6e-13 49.4 13.8 1e-05 25.6 0.0 4.7 4 1 1 5 5 5 3 AAA domain ABC_ATPase PF09818.4 AAS53803.1 - 8.5e-11 41.0 0.2 0.0047 15.5 0.0 4.5 4 1 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 AAS53803.1 - 6e-10 38.5 0.8 0.0012 18.3 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 AAS53803.1 - 1.5e-08 34.8 2.1 0.0025 17.9 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_10 PF12846.2 AAS53803.1 - 6.9e-07 28.9 4.6 0.0054 16.1 0.1 4.4 4 0 0 4 4 4 2 AAA-like domain DUF258 PF03193.11 AAS53803.1 - 1.4e-06 27.5 0.0 0.0073 15.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 AAS53803.1 - 7e-06 26.8 0.2 0.065 14.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AAS53803.1 - 7.6e-06 26.0 2.0 0.053 13.4 0.4 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 AAS53803.1 - 1.3e-05 25.6 8.9 0.012 15.8 0.1 3.3 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 AAS53803.1 - 4.1e-05 23.5 0.1 0.48 10.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SE PF00437.15 AAS53803.1 - 7.2e-05 21.8 0.0 0.073 11.9 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 AAS53803.1 - 0.00019 20.9 0.2 0.4 10.1 0.0 2.9 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_25 PF13481.1 AAS53803.1 - 0.00022 20.6 2.0 1.6 8.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 AAS53803.1 - 0.00038 20.7 0.5 0.26 11.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 AAS53803.1 - 0.00062 19.4 1.2 0.9 9.2 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 AAS53803.1 - 0.00062 19.6 2.3 0.45 10.3 0.0 3.7 4 0 0 4 4 3 1 AAA domain Sigma54_activat PF00158.21 AAS53803.1 - 0.0032 16.9 0.1 7.8 5.9 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF3987 PF13148.1 AAS53803.1 - 0.004 15.7 0.0 0.49 8.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_14 PF13173.1 AAS53803.1 - 0.0049 16.7 0.9 2 8.2 0.0 3.9 4 0 0 4 4 3 1 AAA domain Zeta_toxin PF06414.7 AAS53803.1 - 0.0087 15.1 0.2 0.17 10.9 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin NB-ARC PF00931.17 AAS53803.1 - 0.012 14.4 2.2 8.8 5.0 0.0 3.7 4 0 0 4 4 4 0 NB-ARC domain AAA_5 PF07728.9 AAS53803.1 - 0.013 15.2 0.3 8.5 6.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Miro PF08477.8 AAS53803.1 - 0.013 15.9 1.3 2.1 8.8 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein AAA_24 PF13479.1 AAS53803.1 - 0.015 14.8 0.7 2.8 7.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AAS53803.1 - 0.017 15.2 0.2 7.1 6.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase KaiC PF06745.8 AAS53803.1 - 0.024 13.7 0.6 7.7 5.5 0.1 2.9 3 0 0 3 3 2 0 KaiC AAA_30 PF13604.1 AAS53803.1 - 0.027 14.0 0.1 20 4.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 AAS53803.1 - 0.03 14.1 6.7 0.71 9.6 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function DUF87 SbcCD_C PF13558.1 AAS53803.1 - 0.036 13.9 0.9 3.8 7.4 0.0 3.4 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 AAS53803.1 - 0.039 13.6 6.2 4 7.0 0.1 4.0 4 0 0 4 4 3 0 NACHT domain Arch_ATPase PF01637.13 AAS53803.1 - 0.35 10.5 2.5 0.78 9.3 0.0 2.8 3 0 0 3 3 2 0 Archaeal ATPase AAA_13 PF13166.1 AAS53803.1 - 6.1 5.1 6.5 2 6.7 0.1 3.0 4 0 0 4 4 4 0 AAA domain ThiF PF00899.16 AAS53804.1 - 3.8e-52 175.7 0.1 2.8e-31 108.1 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 AAS53804.1 - 4.5e-46 156.0 0.1 2.9e-45 153.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 AAS53804.1 - 3.9e-33 112.8 5.5 1.7e-23 81.9 0.1 3.1 4 0 0 4 4 4 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 AAS53804.1 - 3.9e-26 90.1 0.1 1.2e-20 72.5 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site SoxY PF13501.1 AAS53804.1 - 0.0096 15.9 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 Sulfur oxidation protein SoxY Mog1 PF04603.7 AAS53805.2 - 1.6e-18 66.9 0.0 3.9e-17 62.5 0.0 2.2 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Gly_transf_sug PF04488.10 AAS53806.1 - 4.5e-13 49.4 0.0 1.2e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TMEM192 PF14802.1 AAS53806.1 - 0.0097 14.7 0.4 0.014 14.2 0.3 1.2 1 0 0 1 1 1 1 TMEM192 family DUF2854 PF11016.3 AAS53806.1 - 0.011 15.3 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) DUF3287 PF11690.3 AAS53806.1 - 0.011 15.7 1.7 0.021 14.8 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF4557 PF15101.1 AAS53806.1 - 0.033 14.0 0.1 0.057 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SlyX PF04102.7 AAS53806.1 - 0.047 14.0 2.2 0.11 12.9 1.5 1.5 1 0 0 1 1 1 0 SlyX CAGE1 PF15066.1 AAS53806.1 - 0.068 11.5 1.6 0.097 11.0 1.1 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family Cast PF10174.4 AAS53806.1 - 0.082 10.9 5.7 0.11 10.4 4.0 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone IncA PF04156.9 AAS53806.1 - 0.16 11.5 2.1 0.25 10.9 1.5 1.2 1 0 0 1 1 1 0 IncA protein Med9 PF07544.8 AAS53806.1 - 0.17 11.6 3.1 0.36 10.5 2.2 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.3 AAS53806.1 - 0.25 11.3 3.4 0.41 10.6 2.3 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Septin PF00735.13 AAS53807.1 - 3.9e-107 357.4 0.0 6.9e-107 356.6 0.0 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 AAS53807.1 - 1.5e-07 31.4 0.0 3.6e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AAS53807.1 - 4.1e-06 26.7 7.0 0.0018 18.0 0.1 2.8 2 1 0 3 3 3 2 Dynamin family DUF258 PF03193.11 AAS53807.1 - 3.5e-05 23.0 0.8 0.0003 20.0 0.5 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 AAS53807.1 - 0.00017 21.8 0.8 0.00069 19.9 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.11 AAS53807.1 - 0.0003 19.9 0.0 0.0003 19.9 0.0 1.9 2 0 0 2 2 2 1 AIG1 family IIGP PF05049.8 AAS53807.1 - 0.00053 18.9 0.1 0.001 17.9 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 AAS53807.1 - 0.00091 19.7 1.1 0.0042 17.5 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 AAS53807.1 - 0.009 15.7 0.0 0.068 12.8 0.0 2.2 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF3450 PF11932.3 AAS53807.1 - 0.01 15.1 2.4 0.015 14.6 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Gasdermin PF04598.7 AAS53807.1 - 0.01 14.5 3.3 0.015 14.0 1.4 1.7 2 0 0 2 2 2 0 Gasdermin family AAA_10 PF12846.2 AAS53807.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain T2SE PF00437.15 AAS53807.1 - 0.042 12.7 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.1 AAS53807.1 - 0.057 14.2 0.3 0.27 12.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 AAS53807.1 - 0.061 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 AAS53807.1 - 0.069 13.0 0.4 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 AAS53807.1 - 0.078 12.4 0.1 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 AAS53807.1 - 0.079 12.4 1.1 0.91 9.0 0.0 2.4 2 1 1 3 3 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 AAS53807.1 - 0.1 11.2 2.1 1.1 7.8 0.0 2.9 3 0 0 3 3 3 0 G-protein alpha subunit FeoB_N PF02421.13 AAS53807.1 - 0.11 11.7 0.3 0.43 9.8 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_23 PF13476.1 AAS53807.1 - 2 8.7 7.3 4.7 7.4 2.5 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 AAS53807.1 - 3.4 7.4 6.2 14 5.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 HSP20 PF00011.16 AAS53808.1 - 4.1e-17 61.9 0.0 5.9e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BON PF04972.12 AAS53808.1 - 0.1 12.4 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 BON domain F-box-like PF12937.2 AAS53809.1 - 7.5e-11 41.5 0.0 1.5e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AAS53809.1 - 0.00049 19.6 0.0 0.0014 18.2 0.0 1.8 1 1 1 2 2 2 1 F-box domain NAD_binding_1 PF00175.16 AAS53810.1 - 5.9e-24 84.7 0.0 9.1e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AAS53810.1 - 7.7e-23 80.4 0.0 1.1e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AAS53810.1 - 0.00011 22.0 0.0 0.0071 16.2 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain DUF4131 PF13567.1 AAS53810.1 - 0.0012 18.2 0.6 0.0025 17.2 0.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4131) FAD_binding_9 PF08021.6 AAS53810.1 - 0.035 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain ALO PF04030.9 AAS53811.1 - 1e-106 356.2 0.5 1.3e-106 355.9 0.3 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 AAS53811.1 - 2.3e-33 114.5 0.1 3.6e-33 113.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AAS53811.1 - 0.01 15.7 0.1 0.027 14.3 0.1 1.7 1 0 0 1 1 1 0 Berberine and berberine like Tubulin PF00091.20 AAS53812.1 - 1.9e-68 230.5 0.0 2.6e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AAS53812.1 - 6.2e-49 165.2 0.0 1e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Sugar_tr PF00083.19 AAS53813.1 - 4.5e-45 154.0 17.8 5.5e-45 153.7 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AAS53813.1 - 6.4e-22 77.7 23.2 2.7e-19 69.1 10.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ku_N PF03731.10 AAS53814.1 - 4.5e-28 98.2 0.0 6.8e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 AAS53814.1 - 2.8e-20 72.6 0.0 4.4e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain SQS_PSY PF00494.14 AAS53815.1 - 9.1e-39 133.3 0.0 1.2e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Pept_tRNA_hydro PF01195.14 AAS53816.1 - 1.1e-42 145.5 0.0 1.3e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Gtr1_RagA PF04670.7 AAS53817.1 - 2e-95 318.3 1.2 2e-95 318.3 0.8 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.17 AAS53817.1 - 4.3e-09 35.9 0.1 9.9e-09 34.7 0.1 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.16 AAS53817.1 - 5.1e-08 32.3 1.1 1e-07 31.3 0.0 2.0 2 1 1 3 3 3 1 ADP-ribosylation factor family Miro PF08477.8 AAS53817.1 - 3e-07 30.9 0.1 8.5e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 AAS53817.1 - 3.4e-06 27.0 0.0 9e-06 25.6 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 AAS53817.1 - 0.0044 17.3 0.2 0.011 16.0 0.0 1.9 2 1 0 2 2 2 1 ABC transporter AIG1 PF04548.11 AAS53817.1 - 0.024 13.7 0.6 0.28 10.2 0.1 2.4 1 1 1 2 2 2 0 AIG1 family AAA_29 PF13555.1 AAS53817.1 - 0.033 13.7 0.1 0.067 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.8 AAS53817.1 - 0.033 13.0 0.3 0.066 12.1 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF815) DUF258 PF03193.11 AAS53817.1 - 0.078 12.1 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pyr_redox_2 PF07992.9 AAS53818.2 - 3.2e-28 99.0 1.7 6.9e-19 68.5 0.0 3.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AAS53818.2 - 3.7e-14 52.8 0.1 8.4e-11 42.1 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AAS53818.2 - 2.9e-09 37.2 0.0 0.00013 22.1 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AAS53818.2 - 0.078 11.8 0.2 15 4.4 0.0 3.2 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Mesothelin PF06060.7 AAS53818.2 - 0.1 10.6 0.0 1.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) NAD_binding_9 PF13454.1 AAS53818.2 - 0.16 11.7 0.9 18 5.0 0.0 3.5 3 1 0 3 3 3 0 FAD-NAD(P)-binding RNB PF00773.14 AAS53819.2 - 1e-72 245.1 0.2 1.4e-72 244.7 0.1 1.2 1 0 0 1 1 1 1 RNB domain PAH PF02671.16 AAS53819.2 - 0.0094 15.5 0.0 0.029 13.9 0.0 1.9 1 0 0 1 1 1 1 Paired amphipathic helix repeat TPR_11 PF13414.1 AAS53819.2 - 0.069 12.8 0.8 0.16 11.6 0.5 1.6 1 0 0 1 1 1 0 TPR repeat MarB PF13999.1 AAS53820.1 - 0.0083 15.6 0.1 0.029 13.9 0.0 1.9 2 0 0 2 2 2 1 MarB protein Ribosomal_L30 PF00327.15 AAS53821.1 - 1e-15 57.0 0.1 3.5e-15 55.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Init_tRNA_PT PF04179.7 AAS53822.3 - 5.4e-138 460.6 0.0 6.1e-138 460.4 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DEAD PF00270.24 AAS53823.3 - 3.6e-46 156.7 0.0 9.7e-44 148.8 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS53823.3 - 4.4e-27 93.7 0.5 8.2e-27 92.8 0.3 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS53823.3 - 4.3e-05 23.4 0.0 0.00034 20.5 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AAS53823.3 - 0.36 10.9 1.7 2.5 8.2 0.6 2.6 2 1 0 2 2 2 0 AAA domain TPR_11 PF13414.1 AAS53824.3 - 1.1e-22 79.4 4.6 2.1e-10 40.0 0.5 3.8 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 AAS53824.3 - 9e-22 75.7 0.4 1.4e-06 27.6 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 AAS53824.3 - 2.8e-20 70.5 1.5 3.1e-05 23.5 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 AAS53824.3 - 1.3e-16 59.5 2.6 0.00082 19.8 0.1 5.5 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 AAS53824.3 - 1.4e-13 51.1 3.0 2.5e-05 24.7 0.1 3.8 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 AAS53824.3 - 2.1e-13 49.3 0.7 0.012 15.7 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.1 AAS53824.3 - 1.9e-10 40.7 1.5 0.036 14.1 0.0 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 AAS53824.3 - 2.7e-09 37.2 4.9 0.025 14.9 0.0 4.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 AAS53824.3 - 2.1e-08 34.0 3.1 3.7e-05 23.5 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 AAS53824.3 - 3.1e-07 29.6 0.1 0.25 11.2 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 AAS53824.3 - 1e-06 28.4 2.9 0.0074 16.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 AAS53824.3 - 1.3e-05 25.2 0.4 14 6.4 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 AAS53824.3 - 3.9e-05 23.1 0.5 1.2 9.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.13 AAS53824.3 - 0.044 13.6 0.0 14 5.6 0.0 3.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain BTAD PF03704.12 AAS53824.3 - 0.072 13.3 2.3 0.16 12.2 0.1 2.5 2 1 1 3 3 3 0 Bacterial transcriptional activator domain Glyco_transf_34 PF05637.7 AAS53825.1 - 4.2e-74 249.0 0.0 5e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 AAS53825.1 - 0.016 14.5 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF273 Nucleotid_trans PF03407.11 AAS53825.1 - 0.016 14.9 0.1 0.03 14.1 0.0 1.5 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase ARID PF01388.16 AAS53826.1 - 1.5e-21 76.0 2.6 1.7e-21 75.8 0.1 2.6 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Nuc_deoxyrib_tr PF05014.10 AAS53826.1 - 0.01 15.7 0.3 0.033 14.0 0.0 2.0 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase PAT1 PF09770.4 AAS53826.1 - 5.4 5.1 69.7 2.1 6.4 24.3 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 ERCC4 PF02732.10 AAS53827.1 - 6.9e-24 84.2 0.8 2.2e-22 79.3 0.0 3.4 4 0 0 4 4 4 1 ERCC4 domain DUF3596 PF12167.3 AAS53827.1 - 0.063 12.8 0.1 0.18 11.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) MTHFR PF02219.12 AAS53828.1 - 1.1e-107 359.4 0.0 1.4e-107 359.0 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Sybindin PF04099.7 AAS53830.1 - 3.5e-38 130.5 0.2 3.9e-22 78.5 0.0 2.0 2 0 0 2 2 2 2 Sybindin-like family Sedlin_N PF04628.8 AAS53830.1 - 8.3e-10 38.6 0.0 1.9e-09 37.5 0.0 1.5 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region DUF3020 PF11223.3 AAS53831.1 - 1e-13 51.4 26.7 5.3e-13 49.1 5.1 6.7 7 0 0 7 7 7 2 Protein of unknown function (DUF3020) zf-C2H2_jaz PF12171.3 AAS53832.1 - 0.00088 19.3 9.6 0.069 13.3 0.6 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 AAS53832.1 - 0.0011 19.2 1.7 0.0011 19.2 1.2 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AAS53832.1 - 0.0017 18.5 0.8 0.0017 18.5 0.5 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 AAS53832.1 - 0.0036 17.5 19.1 0.014 15.7 0.7 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-DHHC PF01529.15 AAS53832.1 - 0.1 11.9 2.6 0.66 9.3 0.0 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase zf-BED PF02892.10 AAS53832.1 - 1.8 8.3 13.3 0.071 12.8 0.6 3.2 3 0 0 3 3 3 0 BED zinc finger TPT PF03151.11 AAS53833.1 - 5.6e-34 117.0 4.6 5.6e-34 117.0 3.2 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 AAS53833.1 - 9.1e-16 57.6 7.9 1.4e-15 57.0 5.5 1.2 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 AAS53833.1 - 0.00063 19.9 2.9 0.00063 19.9 2.0 2.5 2 0 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 AAS53833.1 - 0.0007 19.6 28.3 0.0014 18.6 4.4 3.2 2 2 1 3 3 3 2 EamA-like transporter family FixQ PF05545.6 AAS53833.1 - 0.031 13.9 4.8 0.085 12.5 0.0 3.3 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF485 PF04341.7 AAS53833.1 - 0.068 12.8 0.1 0.068 12.8 0.0 3.8 4 1 0 4 4 4 0 Protein of unknown function, DUF485 COX14 PF14880.1 AAS53833.1 - 0.15 11.7 0.1 0.15 11.7 0.1 2.0 3 0 0 3 3 3 0 Cytochrome oxidase c assembly Multi_Drug_Res PF00893.14 AAS53833.1 - 2.2 8.7 9.0 15 6.1 1.6 2.9 2 1 0 2 2 2 0 Small Multidrug Resistance protein MRP-L28 PF09812.4 AAS53834.1 - 1.2e-40 138.9 0.2 1.4e-40 138.6 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Esterase_phd PF10503.4 AAS53834.1 - 0.014 14.6 0.5 0.022 14.0 0.3 1.3 1 1 0 1 1 1 0 Esterase PHB depolymerase THDPS_N_2 PF14805.1 AAS53834.1 - 0.032 14.1 0.2 0.07 13.0 0.2 1.6 1 1 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal TniQ PF06527.6 AAS53834.1 - 0.2 11.8 2.0 1.1 9.4 0.6 2.0 1 1 1 2 2 2 0 TniQ Ras PF00071.17 AAS53835.1 - 4.3e-51 172.4 0.0 8e-51 171.6 0.0 1.4 2 0 0 2 2 2 1 Ras family Miro PF08477.8 AAS53835.1 - 8.8e-20 71.3 0.0 1.5e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS53835.1 - 2.5e-09 36.6 0.1 3e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AAS53835.1 - 4.7e-07 29.4 0.0 9.9e-07 28.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AAS53835.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 AAS53835.1 - 0.081 13.0 0.3 0.74 9.9 0.2 2.2 1 1 0 1 1 1 0 AAA domain Gly_transf_sug PF04488.10 AAS53836.1 - 2.3e-12 47.2 0.0 4.8e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 AAS53836.1 - 0.099 11.1 0.0 0.6 8.5 0.0 1.9 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Isochorismatase PF00857.15 AAS53837.2 - 2.1e-27 96.1 0.0 3.2e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family NUC153 PF08159.7 AAS53839.1 - 7.3e-12 44.6 4.4 1.4e-11 43.7 3.1 1.5 1 0 0 1 1 1 1 NUC153 domain SNARE PF05739.14 AAS53840.1 - 0.00035 20.1 2.8 0.00035 20.1 2.0 3.6 4 0 0 4 4 4 1 SNARE domain Herpes_UL87 PF03043.9 AAS53840.1 - 0.47 8.7 9.5 0.63 8.3 6.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Ecl1 PF12855.2 AAS53841.1 - 1.1e-15 56.6 3.1 1.1e-15 56.6 2.1 1.8 2 0 0 2 2 2 1 Life-span regulatory factor Metallothio_Pro PF02069.11 AAS53841.1 - 0.0097 15.7 0.9 0.018 14.8 0.6 1.4 1 0 0 1 1 1 1 Prokaryotic metallothionein zf-FCS PF06467.9 AAS53841.1 - 0.034 13.7 0.2 0.059 13.0 0.2 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-MYND PF01753.13 AAS53841.1 - 0.18 11.6 1.7 0.39 10.6 1.2 1.5 1 0 0 1 1 1 0 MYND finger zf-H2C2_2 PF13465.1 AAS53842.1 - 6.2e-11 42.0 13.8 1.3e-07 31.5 1.0 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 AAS53842.1 - 9.5e-10 38.2 9.7 3.6e-05 23.8 0.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS53842.1 - 6.1e-05 23.0 18.1 0.0021 18.2 0.5 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AAS53842.1 - 0.021 14.9 1.1 1.2 9.3 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HEAT_2 PF13646.1 AAS53842.1 - 0.08 13.2 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats zf-C2H2_6 PF13912.1 AAS53842.1 - 0.12 12.2 3.0 0.76 9.7 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Mfp-3 PF04202.8 AAS53843.2 - 0.081 13.1 1.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Foot protein 3 TBPIP PF07106.8 AAS53845.2 - 1.6e-59 200.2 11.6 1.9e-59 199.9 8.1 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cluap1 PF10234.4 AAS53845.2 - 0.00011 21.4 6.0 0.00011 21.4 4.1 1.9 1 1 1 2 2 2 1 Clusterin-associated protein-1 MIS13 PF08202.6 AAS53845.2 - 0.0035 16.4 6.6 0.0048 15.9 4.6 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Mnd1 PF03962.10 AAS53845.2 - 0.0084 15.7 12.2 0.025 14.2 8.5 1.8 1 1 0 1 1 1 1 Mnd1 family Spectrin PF00435.16 AAS53845.2 - 0.014 15.7 6.7 0.014 15.7 4.6 2.2 1 1 2 3 3 3 0 Spectrin repeat Takusan PF04822.8 AAS53845.2 - 0.094 12.4 5.4 0.076 12.7 1.4 2.4 2 1 0 2 2 2 0 Takusan Ku_PK_bind PF08785.6 AAS53845.2 - 0.12 12.2 6.1 0.11 12.3 0.4 2.7 2 1 1 3 3 3 0 Ku C terminal domain like IncA PF04156.9 AAS53845.2 - 0.15 11.6 12.9 0.28 10.7 8.9 1.4 1 1 0 1 1 1 0 IncA protein TPR_MLP1_2 PF07926.7 AAS53845.2 - 0.29 10.8 14.4 0.94 9.2 9.1 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 AAS53845.2 - 0.4 10.0 12.6 0.32 10.4 6.7 2.2 2 1 0 2 2 2 0 Phage minor structural protein GP20 DUF342 PF03961.8 AAS53845.2 - 0.49 8.7 8.3 0.66 8.3 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HsbA PF12296.3 AAS53845.2 - 0.73 9.7 4.0 0.38 10.6 0.5 2.1 2 0 0 2 2 2 0 Hydrophobic surface binding protein A NPV_P10 PF05531.7 AAS53845.2 - 1.1 9.5 7.9 0.49 10.6 2.7 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein LRS4 PF10422.4 AAS53845.2 - 1.2 8.4 8.1 1.6 8.0 5.6 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 TMPIT PF07851.8 AAS53845.2 - 1.2 8.0 5.8 1.8 7.5 4.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF3847 PF12958.2 AAS53845.2 - 1.8 8.3 14.3 1.8 8.3 3.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3847) DUF972 PF06156.8 AAS53845.2 - 2.5 8.5 8.6 4.8 7.5 5.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 AAS53845.2 - 3.3 7.6 12.4 10 6.1 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CCDC-167 PF15188.1 AAS53845.2 - 3.8 7.5 10.9 0.69 9.9 1.6 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Seryl_tRNA_N PF02403.17 AAS53845.2 - 4.5 7.3 18.8 0.16 11.9 2.5 2.9 3 1 1 4 4 3 0 Seryl-tRNA synthetase N-terminal domain Sec20 PF03908.8 AAS53845.2 - 5.4 6.7 6.1 3.9 7.2 0.2 2.8 3 1 0 3 3 3 0 Sec20 DUF1279 PF06916.8 AAS53846.1 - 1e-25 89.8 0.1 1.7e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L24e PF01246.15 AAS53848.1 - 8.8e-35 118.3 0.3 8.8e-35 118.3 0.2 2.2 2 1 0 2 2 2 1 Ribosomal protein L24e GlcNAc PF11397.3 AAS53848.1 - 0.35 9.9 3.3 0.45 9.5 2.3 1.1 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) RR_TM4-6 PF06459.7 AAS53848.1 - 1.2 9.0 8.9 1.4 8.7 6.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_L7Ae PF01248.21 AAS53849.1 - 4.6e-25 86.9 0.1 5.2e-25 86.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2838 PF10998.3 AAS53850.2 - 2.6e-41 139.9 12.0 2.6e-41 139.9 8.3 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) PPR_2 PF13041.1 AAS53851.1 - 7.8e-13 48.1 1.5 5.2e-08 32.7 0.0 3.6 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.1 AAS53851.1 - 0.0034 17.5 4.0 11 6.6 0.0 5.9 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.15 AAS53851.1 - 0.073 13.0 3.3 0.5 10.4 0.0 4.0 4 0 0 4 4 4 0 PPR repeat Cgr1 PF03879.9 AAS53852.1 - 1.1e-38 131.7 34.9 1.3e-38 131.5 24.2 1.0 1 0 0 1 1 1 1 Cgr1 family DnaG_DnaB_bind PF08278.6 AAS53852.1 - 0.42 10.8 12.6 0.41 10.8 8.2 1.3 1 1 0 1 1 1 0 DNA primase DnaG DnaB-binding PRP1_N PF06424.7 AAS53852.1 - 3.1 8.1 13.3 4.2 7.6 9.2 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF4320 PF14208.1 AAS53852.1 - 5.1 7.0 5.5 1.8 8.5 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4320) VSG_B PF13206.1 AAS53852.1 - 6.1 5.8 13.6 1.6 7.7 6.9 1.6 1 1 1 2 2 2 0 Trypanosomal VSG domain G0-G1_switch_2 PF15103.1 AAS53852.1 - 6.2 7.1 9.6 8.8 6.6 6.3 1.5 1 1 0 1 1 1 0 G0/G1 switch protein 2 DUF342 PF03961.8 AAS53852.1 - 8.6 4.6 11.2 10 4.4 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF706 PF05153.10 AAS53853.1 - 2.1e-119 397.4 6.6 2.7e-119 397.1 4.6 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 AAS53853.1 - 0.0029 17.5 0.3 0.33 10.9 0.2 2.6 1 1 0 1 1 1 1 HD domain Glyco_hydro_63 PF03200.11 AAS53854.2 - 3.6e-208 693.2 6.7 2.5e-207 690.4 4.6 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 AAS53854.2 - 4.2e-05 22.4 0.1 8e-05 21.5 0.1 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 AAS53854.2 - 0.00091 17.9 0.2 0.0016 17.1 0.1 1.3 1 0 0 1 1 1 1 Trehalase DUF1793 PF08760.6 AAS53854.2 - 0.013 15.4 0.1 0.18 11.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1793) Rrn6 PF10214.4 AAS53855.2 - 7.5e-178 593.1 17.0 8.7e-178 592.8 11.8 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Trp_syntA PF00290.15 AAS53856.1 - 8.4e-90 299.8 0.0 1.2e-89 299.2 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 AAS53856.1 - 3.5e-46 157.8 0.4 5.8e-46 157.1 0.3 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Med3 PF11593.3 AAS53857.2 - 2.7e-109 365.9 20.0 5e-107 358.4 13.8 2.0 1 1 0 1 1 1 1 Mediator complex subunit 3 fungal zf-C4H2 PF10146.4 AAS53857.2 - 0.005 16.8 1.3 0.022 14.7 0.9 1.9 1 1 0 1 1 1 1 Zinc finger-containing protein Formyl_trans_N PF00551.14 AAS53859.2 - 1.9e-30 105.7 0.0 2.7e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Acyltransferase PF01553.16 AAS53860.2 - 6.6e-10 38.5 0.0 3.4e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase FYVE PF01363.16 AAS53861.1 - 4e-15 55.4 6.6 7.5e-15 54.5 4.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger STT3 PF02516.9 AAS53862.1 - 1.1e-138 463.2 42.3 9.8e-137 456.8 27.0 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 AAS53862.1 - 0.00012 22.0 12.6 0.00012 22.0 8.8 2.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF3635 PF12330.3 AAS53863.1 - 1.2e-11 44.5 0.5 3.8e-11 42.9 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Pkinase_Tyr PF07714.12 AAS53863.1 - 1.3e-05 24.3 0.0 2.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 AAS53863.1 - 0.00024 20.3 0.2 0.00061 19.0 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain dCMP_cyt_deam_1 PF00383.17 AAS53864.1 - 2.7e-09 36.6 0.0 4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 AAS53864.1 - 0.036 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase Telomerase_RBD PF12009.3 AAS53865.1 - 1.4e-25 89.8 1.9 1.4e-25 89.8 1.3 2.2 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 AAS53865.1 - 3.2e-13 49.5 0.2 1.1e-12 47.7 0.1 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AIP3 PF03915.8 AAS53866.1 - 5e-160 533.0 15.2 5e-160 533.0 10.5 1.9 2 0 0 2 2 2 1 Actin interacting protein 3 FliL PF03748.9 AAS53866.1 - 0.041 13.8 3.1 0.11 12.5 0.1 3.2 3 0 0 3 3 3 0 Flagellar basal body-associated protein FliL HSBP1 PF06825.7 AAS53866.1 - 0.078 12.5 3.0 0.33 10.5 0.2 3.1 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF4298 PF14131.1 AAS53866.1 - 0.99 9.3 9.5 0.04 13.7 1.0 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4298) Toxin_52 PF15605.1 AAS53866.1 - 1.2 9.0 5.8 0.55 10.1 0.5 3.1 3 0 0 3 3 3 0 Putative toxin 52 Mus7 PF09462.5 AAS53867.1 - 1.2e-80 272.1 19.0 2.6e-77 261.1 13.2 2.1 1 1 0 1 1 1 1 Mus7/MMS22 family Phage_Mu_F PF04233.9 AAS53867.1 - 0.18 12.3 1.7 2.1 8.9 0.4 2.8 3 0 0 3 3 3 0 Phage Mu protein F like protein Myb_DNA-bind_6 PF13921.1 AAS53868.1 - 0.037 14.1 2.1 0.055 13.5 0.1 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF3542 PF12061.3 AAS53868.1 - 0.12 11.2 0.6 1.5 7.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3542) DUF3408 PF11888.3 AAS53868.1 - 2.8 7.8 10.0 4.3 7.2 5.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3408) Cullin PF00888.17 AAS53869.2 - 3.6e-80 270.1 0.0 1.2e-79 268.4 0.0 1.7 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 AAS53869.2 - 4.7e-20 71.1 0.2 1.3e-19 69.7 0.2 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain TrmB PF01978.14 AAS53869.2 - 0.0093 15.6 0.1 0.096 12.4 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB DUF488 PF04343.8 AAS53869.2 - 0.038 14.3 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF488 zf-CCCH PF00642.19 AAS53870.1 - 2.9e-09 36.3 3.2 2.9e-09 36.3 2.2 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 AAS53870.1 - 1.6e-06 27.6 5.5 2.7e-06 26.9 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AAS53870.1 - 1.8e-06 27.7 7.1 3.2e-06 26.8 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AAS53870.1 - 2.4e-06 27.1 7.5 4.2e-06 26.3 5.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AAS53870.1 - 3.3e-06 27.0 7.5 6e-06 26.1 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AAS53870.1 - 6e-05 22.6 4.0 0.0001 21.8 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AAS53870.1 - 0.0015 18.3 4.5 0.0038 17.0 3.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING BmKX PF09132.5 AAS53870.1 - 0.22 11.4 2.4 0.42 10.5 0.1 2.4 2 0 0 2 2 2 0 BmKX zf-RING_UBOX PF13445.1 AAS53870.1 - 0.29 10.8 2.9 0.61 9.8 2.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 AAS53870.1 - 0.36 10.4 4.0 0.78 9.3 2.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 AAS53870.1 - 0.41 10.7 3.0 1.3 9.1 2.0 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 AAS53870.1 - 0.71 9.7 5.1 1.4 8.7 3.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Pex24p PF06398.6 AAS53871.1 - 1.2e-92 310.5 4.5 1.5e-92 310.1 3.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ribosomal_L38e PF01781.13 AAS53872.1 - 4.7e-28 96.7 2.2 5.2e-28 96.5 1.5 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family ResB PF05140.9 AAS53872.1 - 0.058 11.9 0.0 0.06 11.8 0.0 1.1 1 0 0 1 1 1 0 ResB-like family TFIIF_beta PF02270.10 AAS53873.1 - 3.2e-95 319.0 16.2 5.2e-95 318.3 11.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit AAA_23 PF13476.1 AAS53873.1 - 8.4 6.6 23.4 1.8 8.8 12.5 2.1 2 0 0 2 2 2 0 AAA domain Prp18 PF02840.10 AAS53874.2 - 1.7e-34 118.7 0.0 4e-34 117.5 0.0 1.6 1 1 0 1 1 1 1 Prp18 domain CTP_transf_2 PF01467.21 AAS53875.2 - 5.2e-20 72.0 0.2 6.1e-15 55.6 0.0 2.5 2 1 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 AAS53875.2 - 0.0023 17.5 0.3 7.2 6.2 0.0 3.1 2 1 1 3 3 3 2 FAD synthetase HABP4_PAI-RBP1 PF04774.10 AAS53876.1 - 5.5e-05 23.6 0.1 6.9e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family RE_LlaJI PF09563.5 AAS53876.1 - 0.14 10.8 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 LlaJI restriction endonuclease HSP9_HSP12 PF04119.7 AAS53877.1 - 2.4e-50 168.4 32.7 3.1e-09 36.7 0.4 7.7 2 2 6 8 8 8 7 Heat shock protein 9/12 PMEI PF04043.10 AAS53877.1 - 0.002 18.0 11.9 0.5 10.2 1.3 4.1 1 1 1 2 2 2 1 Plant invertase/pectin methylesterase inhibitor Spt5-NGN PF03439.8 AAS53877.1 - 0.003 17.2 0.1 24 4.7 0.0 4.7 1 1 4 5 5 5 0 Early transcription elongation factor of RNA pol II, NGN section ApoA-II PF04711.8 AAS53877.1 - 0.014 15.2 2.7 14 5.6 0.0 4.9 2 1 4 6 6 6 0 Apolipoprotein A-II (ApoA-II) MIT PF04212.13 AAS53877.1 - 0.016 15.0 9.2 6.8 6.6 0.1 5.8 5 2 0 5 5 5 0 MIT (microtubule interacting and transport) domain Tox-REase-5 PF15648.1 AAS53877.1 - 0.074 13.3 2.7 23 5.3 0.1 3.3 1 1 2 3 3 3 0 Restriction endonuclease fold toxin 5 Erp_C PF06780.6 AAS53877.1 - 0.14 12.0 8.2 0.34 10.7 1.6 3.0 1 1 1 3 3 3 0 Erp protein C-terminus Apo-CII PF05355.6 AAS53877.1 - 0.17 11.7 4.3 60 3.5 0.0 3.8 1 1 5 6 6 6 0 Apolipoprotein C-II Herpes_UL36 PF03586.8 AAS53877.1 - 0.74 8.8 2.7 22 4.0 0.1 3.1 1 1 2 3 3 3 0 Herpesvirus UL36 tegument protein Polysacc_syn_2C PF08485.5 AAS53877.1 - 1.2 8.7 7.0 1.5e+02 2.0 0.0 5.2 6 0 0 6 6 6 0 Polysaccharide biosynthesis protein C-terminal vATP-synt_E PF01991.13 AAS53877.1 - 1.5 8.0 8.2 1.7 7.8 0.2 2.8 1 1 2 3 3 3 0 ATP synthase (E/31 kDa) subunit DnaJ PF00226.26 AAS53878.1 - 9.6e-25 86.1 3.9 2.1e-24 85.0 2.7 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AAS53878.1 - 3.2e-23 81.4 1.8 3.2e-17 62.2 0.1 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AAS53878.1 - 1.1e-09 38.1 20.3 1.8e-09 37.5 14.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Antiterm PF03589.8 AAS53878.1 - 0.017 15.2 5.7 1.5 8.9 0.9 3.6 1 1 2 3 3 3 0 Antitermination protein HypA PF01155.14 AAS53878.1 - 1.2 8.8 6.8 0.46 10.1 0.8 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2781 PF10914.3 AAS53879.1 - 1.5e-31 109.1 15.0 2e-31 108.8 10.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Acetyltransf_1 PF00583.19 AAS53881.1 - 6.8e-14 51.6 0.0 1.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AAS53881.1 - 4.6e-10 39.5 0.0 7.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AAS53881.1 - 0.004 16.9 0.0 0.006 16.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AAS53881.1 - 0.0072 16.4 0.0 0.0087 16.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain LSM PF01423.17 AAS53882.1 - 3e-15 55.5 0.2 3.3e-15 55.3 0.2 1.0 1 0 0 1 1 1 1 LSM domain Pyr_redox_dim PF02852.17 AAS53883.2 - 2.9e-43 146.3 0.1 7.8e-43 144.9 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 AAS53883.2 - 1.4e-38 132.8 13.0 2.1e-37 128.9 9.0 3.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AAS53883.2 - 5e-22 78.0 9.6 2.5e-19 69.4 0.3 4.1 4 1 1 5 5 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AAS53883.2 - 5.8e-12 45.4 6.7 9.8e-11 41.3 0.2 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AAS53883.2 - 3.2e-11 43.0 2.8 1.7e-05 24.7 0.2 3.2 2 1 1 3 3 3 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 AAS53883.2 - 6.2e-11 41.7 5.9 4e-09 35.8 1.9 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 AAS53883.2 - 6e-09 35.2 14.1 0.0052 15.7 1.4 4.5 2 2 2 4 4 4 4 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AAS53883.2 - 6.3e-09 36.1 0.4 2.3e-06 27.8 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AAS53883.2 - 4.5e-08 31.9 8.8 0.00045 18.7 0.6 4.1 3 1 1 4 4 4 3 HI0933-like protein FAD_binding_2 PF00890.19 AAS53883.2 - 1.9e-07 30.2 1.8 1.9e-07 30.2 1.2 2.8 2 1 1 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.16 AAS53883.2 - 0.00011 21.8 1.2 0.017 14.7 0.1 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 AAS53883.2 - 0.00011 21.3 9.2 0.018 14.1 0.4 3.7 2 1 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 AAS53883.2 - 0.00011 21.3 6.3 0.00073 18.7 0.5 2.4 1 1 1 2 2 2 1 Thi4 family K_oxygenase PF13434.1 AAS53883.2 - 0.00014 20.9 0.6 0.51 9.1 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 AAS53883.2 - 0.029 14.0 0.1 0.029 14.0 0.1 2.7 3 0 0 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 AAS53883.2 - 0.043 14.1 0.1 6.5 7.0 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.1 AAS53883.2 - 0.045 13.9 0.9 3 8.1 0.1 3.0 2 0 0 2 2 2 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 AAS53883.2 - 0.061 12.3 0.4 0.19 10.7 0.1 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.7 AAS53883.2 - 0.15 10.9 3.0 2.7 6.8 0.3 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 AAS53883.2 - 0.18 11.1 3.0 0.53 9.6 0.1 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 AAS53883.2 - 0.37 9.3 3.4 1.8 7.0 0.3 2.2 2 0 0 2 2 2 0 Tryptophan halogenase GATA PF00320.22 AAS53884.2 - 2.7e-16 58.5 1.5 2.7e-16 58.5 1.1 2.0 2 0 0 2 2 2 1 GATA zinc finger DUF1752 PF08550.5 AAS53884.2 - 3.8e-09 35.9 2.6 8.9e-09 34.7 1.8 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Fcf2 PF08698.6 AAS53885.1 - 5.8e-33 112.8 0.0 9.1e-33 112.2 0.0 1.2 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing tRNA-synt_2d PF01409.15 AAS53887.1 - 3.2e-89 298.3 0.0 4.4e-89 297.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 AAS53887.1 - 4.5e-07 29.6 0.0 1.8e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 AAS53887.1 - 2.7e-06 26.4 0.4 0.00023 20.0 0.0 3.2 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) PaaX PF07848.7 AAS53887.1 - 0.021 14.8 0.0 1.5 8.8 0.0 3.0 3 0 0 3 3 3 0 PaaX-like protein tRNA-synt_His PF13393.1 AAS53887.1 - 0.037 13.0 0.0 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 Histidyl-tRNA synthetase MSA_2 PF00985.12 AAS53888.1 - 1.9 8.5 9.7 4.2 7.4 6.7 1.5 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family BUD22 PF09073.5 AAS53888.1 - 9.6 5.1 29.4 3.9 6.4 5.4 2.4 2 0 0 2 2 2 0 BUD22 GCR1_C PF12550.3 AAS53889.1 - 5.9e-11 42.0 1.3 6.4e-09 35.5 0.3 2.4 2 0 0 2 2 2 2 Transcriptional activator of glycolytic enzymes DUF3835 PF12927.2 AAS53890.2 - 5.9e-17 62.3 0.0 5.9e-17 62.3 0.0 5.6 5 1 0 5 5 5 2 Domain of unknown function (DUF3835) Prefoldin PF02996.12 AAS53890.2 - 4.5e-08 32.7 0.0 1.4e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Prefoldin subunit EPL1 PF10513.4 AAS53891.2 - 9.4e-35 120.2 2.2 9.4e-35 120.2 1.5 3.4 3 0 0 3 3 3 2 Enhancer of polycomb-like PGAP1 PF07819.8 AAS53892.2 - 6.5e-93 310.4 0.0 1e-92 309.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 AAS53892.2 - 0.0068 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AAS53892.2 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 AAS53892.2 - 0.034 13.4 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.15 AAS53892.2 - 0.048 13.0 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 AAS53892.2 - 0.07 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 AAS53892.2 - 0.17 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) STE2 PF02116.10 AAS53893.1 - 5.5e-96 320.9 28.1 6.7e-96 320.6 19.5 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Hum_adeno_E3A PF05393.6 AAS53893.1 - 0.12 12.0 2.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein CybS PF05328.7 AAS53894.1 - 1.1e-52 177.1 0.0 1.3e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 AAS53894.1 - 0.0036 17.1 0.7 0.04 13.7 0.5 2.1 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Phage_holin_3 PF05106.7 AAS53894.1 - 0.13 12.2 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) Acyltransferase PF01553.16 AAS53895.1 - 0.00069 19.0 0.1 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase LRR_6 PF13516.1 AAS53896.1 - 2.5e-08 33.1 5.5 2 8.7 0.0 7.5 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.28 AAS53896.1 - 3.1e-07 29.5 3.1 5.2 7.4 0.0 7.1 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_4 PF12799.2 AAS53896.1 - 6.7e-06 25.6 7.6 0.17 11.5 0.0 5.5 5 2 1 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AAS53896.1 - 3.5e-05 23.4 6.0 4.8 7.0 0.0 5.8 5 1 1 6 6 6 3 Leucine rich repeat LRR_7 PF13504.1 AAS53896.1 - 0.0018 18.1 7.9 20 5.9 0.0 6.3 7 0 0 7 7 7 2 Leucine rich repeat ACP_syn_III_C PF08541.5 AAS53896.1 - 0.032 14.2 0.1 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal MBF1 PF08523.5 AAS53897.1 - 2.3e-27 94.7 1.3 4.3e-27 93.9 0.9 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 AAS53897.1 - 2.2e-13 49.8 0.1 4e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 AAS53897.1 - 3.8e-06 27.0 0.0 1.1e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 AAS53897.1 - 7.5e-05 22.7 0.1 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.1 AAS53897.1 - 0.043 13.3 0.0 0.094 12.2 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain DBP PF12361.3 AAS53897.1 - 0.046 13.2 0.9 0.05 13.1 0.6 1.1 1 0 0 1 1 1 0 Duffy-antigen binding protein TFIID-31kDa PF02291.10 AAS53898.1 - 1e-53 180.5 0.1 1.1e-53 180.4 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit ChAPs PF09295.5 AAS53899.2 - 1.2e-171 570.8 0.1 1.5e-171 570.5 0.1 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 AAS53899.2 - 0.00099 18.7 5.2 0.042 13.4 0.2 3.1 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 AAS53899.2 - 0.0037 17.9 1.1 20 5.9 0.3 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 AAS53899.2 - 0.035 13.8 0.2 19 5.3 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 AAS53899.2 - 0.038 13.6 0.6 0.18 11.4 0.5 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 AAS53899.2 - 0.12 12.4 4.8 0.34 10.9 0.9 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_32N PF00251.15 AAS53900.1 - 2.3e-88 296.5 9.4 3.2e-88 296.0 6.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 AAS53900.1 - 2.1e-06 28.0 0.0 5.3e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_76 PF03663.9 AAS53901.2 - 5.1e-139 463.7 10.7 6.2e-139 463.4 7.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 zf-C2H2_4 PF13894.1 AAS53902.1 - 3.3e-06 27.0 16.3 0.00096 19.3 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 AAS53902.1 - 0.001 19.2 2.8 0.001 19.2 2.0 4.0 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-BED PF02892.10 AAS53902.1 - 2.4 8.0 10.6 0.059 13.1 0.8 2.9 2 1 1 3 3 3 0 BED zinc finger RGS PF00615.14 AAS53903.1 - 0.093 12.8 0.2 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Regulator of G protein signaling domain Leader_CPA1 PF08252.6 AAS53904.1 - 1.4e-17 62.5 8.6 1.4e-17 62.4 6.0 1.0 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide CPSase_sm_chain PF00988.17 AAS53905.1 - 1.5e-44 150.6 0.0 2.4e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 AAS53905.1 - 1.6e-41 141.8 0.0 2.2e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AAS53905.1 - 1.2e-05 24.8 0.2 0.00044 19.7 0.2 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 AAS53905.1 - 0.044 13.2 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family RCC1 PF00415.13 AAS53907.2 - 2.2e-10 40.5 2.7 4.7e-05 23.5 0.0 3.4 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 AAS53907.2 - 1.6e-08 34.4 0.1 1.5e-07 31.3 0.1 2.3 2 0 0 2 2 2 1 BTB/POZ domain RCC1_2 PF13540.1 AAS53907.2 - 4.4e-08 32.5 2.7 0.0068 15.9 0.0 3.6 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 AAS53907.2 - 0.0026 18.2 0.1 0.11 13.0 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) YihI PF04220.7 AAS53907.2 - 0.26 10.6 0.2 0.47 9.7 0.1 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) SNF2_N PF00176.18 AAS53908.1 - 1.3e-80 270.3 0.8 2.1e-80 269.7 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 AAS53908.1 - 9.5e-45 151.1 2.2 2.6e-44 149.7 1.5 1.8 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 AAS53908.1 - 6.3e-37 126.4 3.1 6.3e-37 126.4 2.1 2.6 2 0 0 2 2 2 1 HAND Helicase_C PF00271.26 AAS53908.1 - 3.7e-16 58.7 0.0 1.7e-15 56.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS53908.1 - 5.8e-09 36.0 3.4 1.2e-08 34.9 0.0 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 AAS53908.1 - 4.9e-07 28.8 0.0 1.5e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 AAS53908.1 - 1.6e-05 24.4 0.2 0.00014 21.4 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 AAS53908.1 - 0.00057 19.8 0.0 0.0036 17.3 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain DEAD_2 PF06733.10 AAS53908.1 - 0.018 14.4 0.1 0.06 12.7 0.0 1.9 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 AAS53908.1 - 0.03 14.2 2.0 0.076 12.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain Ribonuclease_3 PF00636.21 AAS53909.2 - 3.1e-17 63.0 0.0 7.9e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 AAS53909.2 - 1.5e-15 57.2 0.0 3.5e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 AAS53909.2 - 0.00043 20.8 1.1 0.00072 20.0 0.0 2.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif DUF382 PF04037.8 AAS53910.1 - 9.8e-56 187.0 0.1 1.5e-55 186.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 AAS53910.1 - 1.8e-17 62.4 0.5 4e-17 61.3 0.4 1.6 1 0 0 1 1 1 1 PSP Jnk-SapK_ap_N PF09744.4 AAS53911.1 - 0.0032 17.4 2.2 0.0036 17.3 1.5 1.0 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Med11 PF10280.4 AAS53911.1 - 0.028 14.4 1.0 0.037 14.0 0.7 1.2 1 0 0 1 1 1 0 Mediator complex protein Suppressor_APC PF11414.3 AAS53911.1 - 0.037 13.8 2.0 0.051 13.3 1.2 1.4 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Ribosomal_S7e PF01251.13 AAS53911.1 - 0.038 13.4 0.8 0.044 13.2 0.5 1.1 1 0 0 1 1 1 0 Ribosomal protein S7e Laminin_II PF06009.7 AAS53911.1 - 0.047 13.4 1.6 0.058 13.1 1.1 1.1 1 0 0 1 1 1 0 Laminin Domain II Adeno_PIX PF03955.9 AAS53911.1 - 0.065 13.7 0.5 0.075 13.5 0.4 1.1 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) PspA_IM30 PF04012.7 AAS53911.1 - 0.071 12.4 6.2 0.082 12.2 4.3 1.1 1 0 0 1 1 1 0 PspA/IM30 family DUF4398 PF14346.1 AAS53911.1 - 0.085 12.9 4.0 0.13 12.3 2.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) Syntaxin-6_N PF09177.6 AAS53911.1 - 0.085 13.2 1.4 0.094 13.1 0.9 1.1 1 0 0 1 1 1 0 Syntaxin 6, N-terminal eRF1_2 PF03464.10 AAS53911.1 - 0.097 12.9 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 eRF1 domain 2 Syntaxin PF00804.20 AAS53911.1 - 0.11 12.6 2.0 0.15 12.2 1.4 1.2 1 0 0 1 1 1 0 Syntaxin APG6 PF04111.7 AAS53911.1 - 0.19 10.7 4.4 0.19 10.7 3.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 FUSC PF04632.7 AAS53911.1 - 0.2 10.0 0.4 0.21 9.9 0.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_lysis PF03245.8 AAS53911.1 - 0.64 10.0 4.4 2.9 7.9 0.2 1.9 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein DUF2034 PF10356.4 AAS53912.1 - 2.9e-59 199.3 0.0 3.4e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 AAS53912.1 - 0.012 15.3 0.0 4.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Restriction endonuclease Mito_carr PF00153.22 AAS53913.1 - 6.4e-27 93.1 3.4 2e-11 43.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TPT PF03151.11 AAS53914.1 - 3.3e-19 69.0 11.8 3.3e-19 69.0 8.2 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 AAS53914.1 - 7.4e-07 29.2 24.2 0.00023 21.1 0.1 3.2 4 0 0 4 4 4 2 EamA-like transporter family UAA PF08449.6 AAS53914.1 - 0.012 14.5 18.2 0.015 14.2 11.6 1.9 1 1 1 2 2 2 0 UAA transporter family NMN_transporter PF04973.7 AAS53914.1 - 3.4 7.1 10.5 0.16 11.4 0.5 3.0 2 1 1 3 3 3 0 Nicotinamide mononucleotide transporter SIS PF01380.17 AAS53915.1 - 2.4e-17 62.7 0.0 4e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 SIS domain Asparaginase_II PF06089.7 AAS53915.1 - 0.066 11.8 1.2 1.4 7.5 0.1 2.1 1 1 1 2 2 2 0 L-asparaginase II Glyco_transf_28 PF03033.15 AAS53915.1 - 0.074 12.8 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain PPR_3 PF13812.1 AAS53915.1 - 0.19 12.1 1.0 49 4.5 0.0 3.5 3 0 0 3 3 3 0 Pentatricopeptide repeat domain SKN1 PF03935.10 AAS53916.1 - 2.8e-255 847.1 1.8 3.3e-255 846.9 1.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) MCM PF00493.18 AAS53917.1 - 5.1e-139 462.6 0.5 7.3e-139 462.1 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AAS53917.1 - 5.8e-19 68.7 0.7 5.4e-18 65.6 0.0 2.7 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 AAS53917.1 - 2.2e-07 30.2 0.0 1.2e-06 27.9 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AAS53917.1 - 0.0042 16.5 0.0 0.0086 15.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 AAS53917.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AAS53917.1 - 0.0068 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Phosphorylase PF00343.15 AAS53918.1 - 0 1026.8 0.0 0 1026.5 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase Aminotran_1_2 PF00155.16 AAS53919.1 - 3.4e-20 72.3 0.0 4.1e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AAS53919.1 - 0.0072 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Peptidase_S10 PF00450.17 AAS53920.1 - 2.4e-90 303.6 0.0 3.2e-90 303.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase UCH PF00443.24 AAS53922.2 - 3.4e-56 190.3 2.0 4.8e-56 189.8 1.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AAS53922.2 - 6.9e-26 91.3 1.7 1.3e-25 90.4 1.2 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 AAS53922.2 - 9.7e-13 48.0 8.6 9.7e-13 48.0 5.9 2.9 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Phosducin PF02114.11 AAS53923.2 - 1.4e-15 56.7 1.2 1.8e-15 56.3 0.8 1.1 1 0 0 1 1 1 1 Phosducin Mre11_DNA_bind PF04152.9 AAS53924.1 - 6.5e-53 179.1 0.0 1.6e-52 177.9 0.0 1.7 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 AAS53924.1 - 6e-27 94.3 1.1 8.5e-27 93.8 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase His_Phos_1 PF00300.17 AAS53925.1 - 9.2e-34 116.8 1.8 1.1e-33 116.5 1.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Rhodanese PF00581.15 AAS53926.1 - 1.1e-17 64.4 0.0 1.4e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.15 AAS53927.1 - 8.3e-13 48.6 0.0 9.8e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain VHP PF02209.14 AAS53927.1 - 0.011 15.4 0.1 0.06 13.0 0.1 2.0 2 0 0 2 2 2 0 Villin headpiece domain DUF947 PF06102.7 AAS53928.1 - 1.2e-44 152.1 21.5 1.2e-44 152.1 14.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF947) Matrilin_ccoil PF10393.4 AAS53928.1 - 0.063 12.6 2.4 0.14 11.5 1.6 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin GH-E PF14410.1 AAS53928.1 - 0.16 12.0 2.1 0.48 10.5 1.5 1.8 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues SPARC_Ca_bdg PF10591.4 AAS53928.1 - 4.9 7.2 9.4 1.6 8.8 3.5 2.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MRP_L53 PF10780.4 AAS53929.1 - 2.4e-21 75.4 0.7 3.2e-21 75.0 0.5 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Cytochrom_B559a PF00284.15 AAS53929.1 - 0.2 11.2 0.6 2 7.9 0.0 2.4 3 0 0 3 3 3 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit Thioredoxin PF00085.15 AAS53930.2 - 1.8e-22 78.9 0.0 5.2e-22 77.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 AAS53930.2 - 3.7e-07 30.3 0.1 1.1e-06 28.8 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 AAS53930.2 - 1.4e-06 28.2 0.1 3.4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 AAS53930.2 - 6.9e-05 22.8 0.0 0.0002 21.3 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 AAS53930.2 - 0.026 14.0 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.1 AAS53930.2 - 0.12 12.1 0.1 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain AMMECR1 PF01871.12 AAS53931.1 - 6.8e-36 122.9 0.0 8.4e-36 122.6 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 adh_short PF00106.20 AAS53932.1 - 3.7e-37 127.8 0.1 8e-37 126.7 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 AAS53932.1 - 1.2e-15 57.9 0.2 1.5e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AAS53932.1 - 4.1e-14 52.6 0.0 6.4e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 AAS53932.1 - 6.6e-05 22.1 0.0 0.00052 19.2 0.0 1.9 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 AAS53932.1 - 0.00014 21.5 0.3 0.00029 20.5 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 AAS53932.1 - 0.00072 19.0 0.1 0.0013 18.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 AAS53932.1 - 0.0039 16.1 0.3 0.0073 15.2 0.2 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 AAS53932.1 - 0.0059 16.6 0.1 0.0096 15.9 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding SNF2_N PF00176.18 AAS53933.2 - 1.6e-80 270.0 0.1 1.6e-80 270.0 0.1 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AAS53933.2 - 2.1e-17 62.7 0.1 3.1e-16 58.9 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 AAS53933.2 - 1.1e-16 60.7 4.9 1.1e-16 60.7 3.4 3.7 3 1 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex Bromodomain PF00439.20 AAS53933.2 - 5.3e-14 51.9 0.3 1.7e-13 50.3 0.2 1.9 1 0 0 1 1 1 1 Bromodomain QLQ PF08880.6 AAS53933.2 - 2.7e-12 45.8 0.2 2.7e-12 45.8 0.1 2.5 3 0 0 3 3 3 1 QLQ IU_nuc_hydro PF01156.14 AAS53933.2 - 0.81 8.8 4.9 0.15 11.2 0.3 2.0 2 0 0 2 2 2 0 Inosine-uridine preferring nucleoside hydrolase TAFII55_N PF04658.8 AAS53934.1 - 3.9e-57 192.2 0.1 7.5e-57 191.3 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region RrnaAD PF00398.15 AAS53935.2 - 5.7e-47 159.9 0.0 6.9e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase S1 PF00575.18 AAS53937.2 - 6.5e-54 179.9 30.5 4.5e-12 45.8 0.3 12.2 12 0 0 12 12 12 9 S1 RNA binding domain TPR_19 PF14559.1 AAS53937.2 - 3.2e-09 36.9 0.1 0.0036 17.5 0.0 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 AAS53937.2 - 7.3e-09 36.0 2.1 0.0034 18.0 0.1 4.2 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 AAS53937.2 - 3e-08 33.5 5.6 0.035 14.7 0.0 5.1 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 AAS53937.2 - 4.8e-05 23.2 0.5 0.47 10.4 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 AAS53937.2 - 0.00016 21.2 0.0 0.43 10.2 0.0 3.0 2 0 0 2 2 2 2 TPR repeat Suf PF05843.9 AAS53937.2 - 0.00049 19.9 11.7 0.0023 17.7 0.0 3.7 2 1 2 4 4 4 3 Suppressor of forked protein (Suf) NRDE-2 PF08424.5 AAS53937.2 - 0.0025 16.7 0.7 0.057 12.2 0.2 2.3 1 1 0 2 2 2 1 NRDE-2, necessary for RNA interference RNA_pol_Rbc25 PF08292.7 AAS53937.2 - 0.03 14.5 0.9 0.38 10.9 0.0 3.5 2 1 0 3 3 3 0 RNA polymerase III subunit Rpc25 TPR_2 PF07719.12 AAS53937.2 - 1.7 8.7 6.7 23 5.2 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat P5-ATPase PF12409.3 AAS53938.2 - 3e-38 130.3 0.9 7.1e-38 129.1 0.6 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 AAS53938.2 - 3.6e-29 101.4 0.0 7.5e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 AAS53938.2 - 5.7e-26 91.8 0.0 1.2e-25 90.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AAS53938.2 - 3.8e-18 66.6 0.0 2.4e-17 64.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AAS53938.2 - 8.4e-07 28.8 0.0 1.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AAS53938.2 - 0.012 15.1 0.0 0.35 10.4 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Mpv17_PMP22 PF04117.7 AAS53939.2 - 1.6e-18 66.0 0.8 1.6e-18 66.0 0.5 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF962 PF06127.6 AAS53939.2 - 0.055 13.3 0.0 0.25 11.2 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF962) S10_plectin PF03501.10 AAS53940.1 - 5.2e-42 141.6 0.2 6.2e-42 141.3 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF505 PF04458.7 AAS53940.1 - 0.023 12.8 0.2 0.027 12.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF505) YjcQ PF09639.5 AAS53940.1 - 0.046 13.8 0.1 0.068 13.2 0.1 1.3 1 0 0 1 1 1 0 YjcQ protein HTH_45 PF14947.1 AAS53940.1 - 0.11 12.3 0.4 0.17 11.6 0.3 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix tRNA-synt_1c_C PF03950.13 AAS53940.1 - 0.12 11.9 0.1 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain PadR PF03551.9 AAS53940.1 - 0.83 9.4 5.4 0.17 11.6 1.2 1.8 2 1 0 2 2 2 0 Transcriptional regulator PadR-like family EF-hand_7 PF13499.1 AAS53941.1 - 6.8e-06 26.1 1.7 0.096 12.8 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AAS53941.1 - 0.00012 21.6 1.9 1.3 9.1 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain Cullin_binding PF03556.10 AAS53941.1 - 0.053 13.6 0.6 0.094 12.8 0.4 1.3 1 0 0 1 1 1 0 Cullin binding GRP PF07172.6 AAS53941.1 - 1.5 9.3 19.5 3.4 8.1 13.5 1.5 1 0 0 1 1 1 0 Glycine rich protein family Septin PF00735.13 AAS53942.2 - 9.4e-98 326.6 0.0 1.6e-97 325.9 0.0 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 AAS53942.2 - 4.5e-06 26.5 0.0 1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AAS53942.2 - 5.2e-05 23.1 0.2 0.059 13.1 0.1 2.8 1 1 1 2 2 2 2 Dynamin family DUF258 PF03193.11 AAS53942.2 - 9.7e-05 21.6 0.2 0.00031 19.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AIG1 PF04548.11 AAS53942.2 - 0.00072 18.7 0.2 0.0057 15.7 0.0 2.3 2 0 0 2 2 2 1 AIG1 family FtsK_SpoIIIE PF01580.13 AAS53942.2 - 0.0079 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_24 PF13479.1 AAS53942.2 - 0.015 14.8 0.1 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 AAS53942.2 - 0.019 15.4 0.0 0.063 13.7 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 AAS53942.2 - 0.032 13.6 0.6 0.091 12.1 0.1 2.1 2 1 0 2 2 2 0 AAA-like domain T2SE PF00437.15 AAS53942.2 - 0.047 12.5 0.0 0.088 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 AAS53942.2 - 0.089 12.5 0.4 0.26 10.9 0.2 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 AAS53942.2 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 NACHT domain DUF87 PF01935.12 AAS53942.2 - 0.67 9.7 0.0 0.67 9.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 ABC_tran PF00005.22 AAS53942.2 - 7.8 6.8 7.2 0.42 10.8 0.2 2.4 3 1 0 3 3 3 0 ABC transporter FA_hydroxylase PF04116.8 AAS53943.1 - 2.5e-16 60.0 19.9 2.5e-16 60.0 13.8 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily GATase_5 PF13507.1 AAS53944.1 - 3.7e-98 327.5 0.0 5.6e-98 326.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 AAS53944.1 - 2.6e-50 170.4 0.4 2.2e-28 99.1 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 AAS53944.1 - 6.8e-22 77.5 0.0 2e-21 75.9 0.0 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain DUF2462 PF09495.5 AAS53945.1 - 4.3e-20 72.2 13.9 5.5e-20 71.8 9.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) 60KD_IMP PF02096.15 AAS53946.1 - 2.3e-15 56.8 1.4 1.2e-12 47.9 0.4 2.0 2 0 0 2 2 2 2 60Kd inner membrane protein Spt4 PF06093.8 AAS53947.1 - 5.8e-29 99.8 0.5 6.7e-29 99.5 0.4 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-TFIIB PF13453.1 AAS53947.1 - 0.033 13.3 0.5 0.062 12.4 0.3 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger Glutaredoxin PF00462.19 AAS53948.1 - 5.4e-05 23.1 0.0 0.00014 21.8 0.0 1.8 1 1 0 1 1 1 1 Glutaredoxin DUF953 PF06110.6 AAS53948.1 - 0.0012 18.2 0.3 0.0014 18.0 0.2 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 AAS53948.1 - 0.0095 15.5 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin MFS_1 PF07690.11 AAS53949.2 - 7.8e-20 70.8 24.7 7.8e-20 70.8 17.1 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily Ribosomal_S8 PF00410.14 AAS53950.1 - 2.4e-26 92.0 0.1 3.2e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 zf-C2H2 PF00096.21 AAS53951.1 - 2.8e-07 30.4 12.8 6.1e-05 23.1 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS53951.1 - 2.7e-06 27.3 12.8 0.00057 20.0 1.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AAS53951.1 - 0.00011 22.2 15.4 0.00018 21.6 2.7 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.1 AAS53951.1 - 0.62 10.4 9.9 0.063 13.5 1.0 3.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Arrestin_C PF02752.17 AAS53952.2 - 3.2e-11 43.4 0.0 5.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 AAS53952.2 - 6.6e-07 29.2 0.0 0.00024 20.9 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain F-box PF00646.28 AAS53953.1 - 2.6e-06 26.9 0.5 1.1e-05 24.9 0.3 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 AAS53953.1 - 9.3e-05 22.0 0.8 9.3e-05 22.0 0.6 2.3 2 0 0 2 2 2 1 F-box-like HSP70 PF00012.15 AAS53954.1 - 8.4e-213 707.6 8.1 1e-212 707.3 5.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AAS53954.1 - 1e-16 60.4 2.6 3.7e-14 52.0 0.6 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 AAS53954.1 - 0.00021 21.0 0.0 0.00039 20.0 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4200 PF13863.1 AAS53954.1 - 0.2 11.6 2.1 0.63 9.9 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF964 PF06133.6 AAS53954.1 - 0.24 11.4 3.9 0.12 12.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF964) P21-Arc PF04062.9 AAS53955.1 - 1.5e-78 262.5 0.0 1.7e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit CNH PF00780.17 AAS53956.2 - 7.2e-82 274.8 0.3 1.3e-81 274.0 0.0 1.5 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 AAS53956.2 - 7.6e-36 123.0 0.0 2.2e-35 121.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 AAS53956.2 - 6.2e-33 114.1 0.2 1.4e-32 113.0 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 AAS53956.2 - 1.1e-13 50.7 0.0 2.3e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ELO PF01151.13 AAS53957.1 - 9.6e-62 208.5 20.3 1.2e-61 208.2 14.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family zf-BED PF02892.10 AAS53958.1 - 5.1e-05 22.9 9.0 0.00011 21.9 6.2 1.6 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_jaz PF12171.3 AAS53959.1 - 0.0006 19.8 4.8 0.0043 17.1 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 AAS53959.1 - 0.00068 19.8 2.8 0.00068 19.8 2.0 5.0 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 AAS53959.1 - 0.00082 19.1 0.7 0.00082 19.1 0.5 4.2 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 AAS53959.1 - 0.00089 19.4 1.6 0.00089 19.4 1.1 4.8 4 1 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AAS53959.1 - 0.002 18.3 0.6 0.002 18.3 0.4 5.3 4 1 1 5 5 5 1 Zinc-finger double domain Cytochrome_C554 PF13435.1 AAS53959.1 - 1.3 9.0 10.5 0.054 13.5 2.5 1.9 2 0 0 2 2 2 0 Cytochrome c554 and c-prime SAE2 PF08573.5 AAS53959.1 - 1.4 9.6 6.8 1.6 9.4 0.1 2.5 2 1 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus zf-C2HC_2 PF13913.1 AAS53959.1 - 7.5 6.3 11.5 0.55 9.9 0.8 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type FA_desaturase PF00487.19 AAS53960.1 - 4.3e-25 88.6 19.4 6.6e-25 88.0 13.5 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 AAS53960.1 - 6.5e-06 26.2 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) KRE9 PF05390.6 AAS53961.2 - 5.3e-36 123.2 4.4 8.5e-36 122.5 3.0 1.2 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 AAS53961.2 - 5.6e-11 42.7 0.0 1.3e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family La PF05383.12 AAS53962.2 - 4e-22 77.7 0.0 9e-22 76.6 0.0 1.6 2 0 0 2 2 2 1 La domain RRM_6 PF14259.1 AAS53962.2 - 0.0049 16.8 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Acyltransferase PF01553.16 AAS53963.2 - 5.4e-33 113.2 0.0 9.2e-33 112.4 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase Ribosomal_L13e PF01294.13 AAS53963.2 - 0.079 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L13e FBPase PF00316.15 AAS53964.2 - 1.6e-134 447.7 0.0 1.9e-134 447.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase DUF4228 PF14009.1 AAS53965.1 - 4.9 7.2 6.6 6.2 6.9 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) MFS_1 PF07690.11 AAS53966.1 - 3.5e-06 25.9 56.9 2.9e-05 22.9 18.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily SecY PF00344.15 AAS53967.1 - 5.3e-90 301.8 12.9 6.6e-90 301.5 9.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 AAS53967.1 - 7.3e-18 63.7 0.5 3.8e-17 61.4 0.1 2.5 2 0 0 2 2 2 1 Plug domain of Sec61p Glyco_hydro_85 PF03644.8 AAS53968.2 - 1.6e-74 250.8 1.8 2.3e-74 250.3 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Transp_cyt_pur PF02133.10 AAS53969.2 - 2.3e-152 507.5 33.7 2.8e-152 507.3 23.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NTP_transferase PF00483.18 AAS53970.1 - 8.9e-49 166.0 0.0 1.2e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 AAS53970.1 - 2.5e-11 43.9 0.0 3.3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 AAS53970.1 - 7.8e-11 40.9 5.5 4.1e-07 29.2 0.8 3.7 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) IspD PF01128.14 AAS53970.1 - 0.14 11.6 0.0 0.68 9.4 0.0 1.9 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.1 AAS53970.1 - 0.89 9.1 7.4 0.39 10.3 0.5 3.2 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase Ank PF00023.25 AAS53971.2 - 3.3e-14 51.8 0.2 1.9e-05 24.2 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 AAS53971.2 - 5.8e-14 52.2 0.0 1.5e-07 31.6 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AAS53971.2 - 8.7e-13 48.4 0.0 1.4e-06 28.6 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 AAS53971.2 - 6e-12 45.4 0.3 8.4e-05 22.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AAS53971.2 - 1.1e-08 34.4 0.6 0.0051 16.9 0.0 4.3 5 0 0 5 5 4 2 Ankyrin repeat KilA-N PF04383.8 AAS53971.2 - 2.9e-07 30.1 0.2 1.6e-06 27.7 0.2 2.2 1 1 0 1 1 1 1 KilA-N domain DUF947 PF06102.7 AAS53971.2 - 0.0032 17.2 3.6 0.0078 16.0 2.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF947) DUF2730 PF10805.3 AAS53971.2 - 0.075 12.7 3.0 0.17 11.6 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) TBPIP PF07106.8 AAS53971.2 - 0.25 10.8 8.7 0.14 11.7 3.9 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 AAS53971.2 - 1.4 9.2 7.5 2.3 8.5 1.7 3.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 AAS53971.2 - 5.6 6.7 8.3 2.2 8.0 1.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Y_phosphatase3 PF13350.1 AAS53972.1 - 2.4e-42 144.9 0.0 6.1e-42 143.6 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Abhydrolase_6 PF12697.2 AAS53972.1 - 6.1e-15 55.7 0.3 1.9e-14 54.1 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AAS53972.1 - 1.2e-13 50.9 0.0 2.8e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AAS53972.1 - 1.1e-07 31.5 0.0 7e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Y_phosphatase3C PF13348.1 AAS53972.1 - 4.1e-07 30.0 0.0 1.2e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region DUF2673 PF10880.3 AAS53972.1 - 0.024 14.6 0.1 0.12 12.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) Sugar_tr PF00083.19 AAS53973.1 - 9.8e-111 370.4 32.3 1.1e-110 370.2 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AAS53973.1 - 3.1e-25 88.6 47.5 4.9e-22 78.1 18.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2868 PF11067.3 AAS53973.1 - 0.2 10.7 0.0 0.38 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) MutS_V PF00488.16 AAS53974.1 - 4.8e-97 323.9 0.1 8.9e-97 323.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AAS53974.1 - 7.5e-32 110.7 2.1 1.5e-31 109.7 0.3 2.2 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 AAS53974.1 - 6.7e-17 61.8 0.1 2.2e-16 60.1 0.1 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 AAS53974.1 - 1.2e-16 60.6 3.4 2.3e-16 59.7 0.3 2.8 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.15 AAS53974.1 - 8.6e-09 35.4 0.0 2.9e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 MutS domain I DASH_Dad2 PF08654.5 AAS53974.1 - 0.015 15.2 0.7 4.3 7.3 0.1 2.9 2 0 0 2 2 2 0 DASH complex subunit Dad2 Kinesin-relat_1 PF12711.2 AAS53974.1 - 2 8.8 5.9 18 5.8 0.7 3.4 3 0 0 3 3 3 0 Kinesin motor ADIP PF11559.3 AAS53975.2 - 0.35 10.7 47.0 0.21 11.5 5.7 4.9 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 AAS53975.2 - 3.8 7.2 48.2 0.06 13.1 10.8 3.9 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) GAS PF13851.1 AAS53975.2 - 8 5.5 50.3 0.22 10.7 1.2 4.6 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Med9 PF07544.8 AAS53975.2 - 9.8 5.9 29.8 1.3 8.8 6.0 4.5 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 PQ-loop PF04193.9 AAS53976.1 - 1.5e-42 142.9 17.0 3.2e-24 84.2 0.8 2.8 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 AAS53976.1 - 1.1 9.2 6.5 0.75 9.7 0.2 2.7 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange WHIM1 PF15612.1 AAS53977.1 - 0.0031 17.3 0.0 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 PI-PLC-X PF00388.14 AAS53978.1 - 9.2e-14 51.0 0.0 1.4e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Choline_sulf_C PF12411.3 AAS53978.1 - 6.2 6.7 9.6 1.5 8.6 0.5 2.7 2 1 1 3 3 3 0 Choline sulfatase enzyme C terminal WD40 PF00400.27 AAS53979.2 - 0.0041 16.9 0.6 2.5 8.1 0.0 4.6 5 1 1 6 6 6 1 WD domain, G-beta repeat BPL_LplA_LipB PF03099.14 AAS53980.1 - 5.8e-17 61.8 0.1 1.2e-16 60.8 0.1 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family UPF0086 PF01868.11 AAS53981.1 - 9.3e-12 44.4 0.0 1.7e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 COMPASS-Shg1 PF05205.7 AAS53982.1 - 2.7e-23 82.2 0.0 3.4e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 SecY PF00344.15 AAS53984.1 - 9.2e-53 179.3 16.3 1.2e-52 178.9 11.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 AAS53984.1 - 1.8e-08 33.7 0.1 4.7e-08 32.4 0.1 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p DUF1155 PF06633.6 AAS53984.1 - 4 6.7 5.6 24 4.2 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1155) RRF PF01765.14 AAS53985.1 - 0.015 14.7 0.1 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Methyltransf_PK PF05891.7 AAS53986.2 - 3.4e-89 297.8 0.0 3.9e-89 297.6 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 AAS53986.2 - 3.1e-05 24.5 0.0 5.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AAS53986.2 - 5.9e-05 23.4 0.0 0.0001 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AAS53986.2 - 0.00016 21.4 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AAS53986.2 - 0.003 17.8 0.0 0.0052 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AAS53986.2 - 0.042 14.3 0.0 0.083 13.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF2288 PF10052.4 AAS53986.2 - 0.043 13.5 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) Methyltransf_2 PF00891.13 AAS53986.2 - 0.099 11.8 0.0 0.2 10.8 0.0 1.4 2 0 0 2 2 2 0 O-methyltransferase RhoGAP PF00620.22 AAS53987.2 - 3.5e-40 137.1 0.0 8.3e-40 135.8 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 AAS53987.2 - 2e-11 43.9 0.3 6.6e-11 42.2 0.0 2.0 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain MCM_N PF14551.1 AAS53987.2 - 0.014 15.8 1.7 3.5 8.1 0.0 2.6 2 1 0 2 2 2 0 MCM N-terminal domain Cullin PF00888.17 AAS53988.1 - 5.7e-10 38.3 1.3 2.3e-09 36.3 0.0 2.2 2 0 0 2 2 2 1 Cullin family MRP-L27 PF09809.4 AAS53989.1 - 1.3e-29 102.0 0.1 2.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF2012 PF09430.5 AAS53990.1 - 0.018 14.9 0.1 0.04 13.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) Beach PF02138.13 AAS53991.2 - 8e-108 359.9 0.0 2.1e-107 358.6 0.0 1.8 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 AAS53991.2 - 9.8e-11 41.4 0.0 2.6e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 AAS53991.2 - 0.00044 20.5 0.0 0.0024 18.1 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily AAA_22 PF13401.1 AAS53992.1 - 2.3e-09 37.4 0.0 8e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 AAS53992.1 - 2.6e-07 30.8 0.4 1.5e-06 28.3 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 AAS53992.1 - 2.8e-07 30.1 0.1 7.4e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 CDC6, C terminal AAA_16 PF13191.1 AAS53992.1 - 4.2e-06 26.8 0.1 0.00015 21.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 AAS53992.1 - 0.00078 19.1 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 AAS53992.1 - 0.034 13.7 0.1 0.43 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 AAS53992.1 - 0.059 12.3 0.0 0.14 11.1 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 AAS53992.1 - 0.059 12.8 0.1 0.69 9.3 0.1 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase Xan_ur_permease PF00860.15 AAS53993.1 - 4.6e-59 199.8 33.5 7.7e-59 199.1 23.2 1.3 1 0 0 1 1 1 1 Permease family Myb_DNA-binding PF00249.26 AAS53994.2 - 7.1e-15 54.7 0.0 4.2e-06 26.7 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AAS53994.2 - 0.00015 21.8 3.3 0.0025 17.8 0.1 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain ELO PF01151.13 AAS53995.1 - 2.1e-61 207.4 23.1 2.4e-61 207.1 16.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RNase_PH PF01138.16 AAS53996.2 - 3.2e-25 88.9 0.0 5.2e-24 85.0 0.0 2.1 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 PfkB PF00294.19 AAS53997.1 - 1.6e-47 162.0 2.8 5.1e-47 160.4 2.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase UCH PF00443.24 AAS53998.2 - 5.5e-90 301.1 0.0 2.3e-89 299.0 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AAS53998.2 - 4.8e-22 78.7 1.2 2.5e-12 46.8 0.0 2.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 AAS53998.2 - 6.2e-05 23.3 0.6 0.00021 21.6 0.1 2.3 2 0 0 2 2 2 1 DUSP domain CW_binding_1 PF01473.15 AAS53998.2 - 0.013 15.6 2.1 0.037 14.1 1.5 1.9 1 0 0 1 1 1 0 Putative cell wall binding repeat DUF365 PF04033.7 AAS53998.2 - 0.019 14.9 0.4 0.05 13.5 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF365) TF_Zn_Ribbon PF08271.7 AAS53998.2 - 0.88 8.9 3.2 2.5 7.4 0.2 2.8 2 0 0 2 2 2 0 TFIIB zinc-binding SPX PF03105.14 AAS53999.2 - 1.3e-46 159.6 6.0 1.3e-46 159.6 4.2 1.4 2 0 0 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 AAS53999.2 - 2.2e-23 82.8 44.4 3.1e-23 82.3 30.8 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 AAS53999.2 - 2.5e-13 49.3 45.6 8.9e-13 47.5 17.1 2.2 1 1 1 2 2 2 2 Citrate transporter Aconitase PF00330.15 AAS54000.2 - 1.1e-166 554.9 0.0 3.3e-166 553.3 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AAS54000.2 - 3.8e-41 140.2 0.0 7.3e-41 139.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 AAS54000.2 - 0.16 10.5 0.0 0.32 9.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF521) RasGEF PF00617.14 AAS54001.2 - 3.5e-44 150.7 0.1 7.9e-44 149.6 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 AAS54001.2 - 1.8e-14 53.6 4.3 4e-14 52.5 0.2 2.8 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 AAS54001.2 - 0.00044 19.5 0.1 0.00096 18.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AAS54001.2 - 0.0089 15.5 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AAS54001.2 - 0.031 13.7 0.1 0.27 10.7 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain CRAL_TRIO_2 PF13716.1 AAS54002.1 - 1e-32 113.1 0.4 2.7e-32 111.7 0.3 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 AAS54002.1 - 1.2e-07 31.5 0.2 5.3e-07 29.3 0.1 2.1 1 1 0 1 1 1 1 RhoGAP domain CoaE PF01121.15 AAS54002.1 - 0.047 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase RTC4 PF14474.1 AAS54003.2 - 3.7e-33 114.1 0.0 7.6e-33 113.0 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain HSP20 PF00011.16 AAS54004.1 - 9.4e-09 35.0 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family WD40 PF00400.27 AAS54005.1 - 2.2e-16 59.0 8.4 1.9e-06 27.5 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Peptidase_C37 PF05416.7 AAS54005.1 - 0.13 10.5 2.9 4 5.6 0.0 2.9 2 1 1 3 3 3 0 Southampton virus-type processing peptidase MRP-L46 PF11788.3 AAS54006.1 - 9.7e-37 126.0 0.0 1.6e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 RRM_6 PF14259.1 AAS54007.2 - 5.4e-08 32.7 0.0 1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AAS54007.2 - 5.8e-08 32.2 0.0 1.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS54007.2 - 8e-05 22.4 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 AAS54007.2 - 0.0096 15.3 0.0 0.027 13.9 0.0 1.8 1 0 0 1 1 1 1 Sporulation protein family 7 CTK3 PF12243.3 AAS54007.2 - 0.022 14.4 0.1 0.43 10.2 0.0 2.2 1 1 1 2 2 2 0 CTD kinase subunit gamma CTK3 MIP-T3 PF10243.4 AAS54007.2 - 0.036 12.5 15.9 0.051 12.0 11.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RNA_bind PF08675.6 AAS54007.2 - 0.085 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA binding domain PAT1 PF09770.4 AAS54007.2 - 1.5 6.9 41.2 0.012 13.9 10.9 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 AAS54008.2 - 2.1e-28 100.0 4.1 2.1e-28 100.0 2.8 8.3 2 1 3 5 5 2 1 AAA domain Rad50_zn_hook PF04423.9 AAS54008.2 - 1e-17 63.3 3.7 3.3e-16 58.4 2.5 4.1 1 0 0 1 1 1 1 Rad50 zinc hook motif SbcCD_C PF13558.1 AAS54008.2 - 4.4e-11 42.5 0.0 1.2e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 AAS54008.2 - 2.1e-08 33.6 0.1 2.1e-08 33.6 0.0 2.7 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AAS54008.2 - 5.8e-08 33.0 4.7 7.1e-05 22.9 1.5 5.3 4 2 2 6 6 6 2 AAA domain AAA_13 PF13166.1 AAS54008.2 - 6.7e-07 28.1 135.4 5.1e-05 21.9 0.0 6.9 3 2 2 6 6 6 4 AAA domain AAA_29 PF13555.1 AAS54008.2 - 0.0049 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NPV_P10 PF05531.7 AAS54008.2 - 0.013 15.7 0.4 0.013 15.7 0.3 9.1 6 4 4 10 10 10 0 Nucleopolyhedrovirus P10 protein ABC_tran PF00005.22 AAS54008.2 - 0.015 15.5 0.0 0.015 15.5 0.0 7.7 4 2 0 4 4 2 0 ABC transporter DUF972 PF06156.8 AAS54008.2 - 0.022 15.0 0.8 0.022 15.0 0.6 11.6 3 3 7 11 11 10 0 Protein of unknown function (DUF972) AAA_19 PF13245.1 AAS54008.2 - 0.21 11.3 0.1 0.58 9.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 AAS54008.2 - 0.31 10.9 0.0 0.31 10.9 0.0 4.3 4 2 1 5 5 5 0 AAA ATPase domain FUSC PF04632.7 AAS54008.2 - 5.3 5.3 21.9 0.19 10.1 0.2 3.7 2 1 2 4 4 4 0 Fusaric acid resistance protein family RNA_pol_I_A49 PF06870.7 AAS54009.1 - 8.4e-139 462.4 0.2 9.5e-139 462.2 0.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor PhageMin_Tail PF10145.4 AAS54009.1 - 0.13 11.9 4.3 0.12 12.0 1.1 2.0 2 0 0 2 2 2 0 Phage-related minor tail protein zf-CSL PF05207.8 AAS54010.1 - 2.7e-19 68.3 0.1 3.7e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 AAS54010.1 - 1.5e-16 59.8 0.0 2e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Zn_Tnp_IS1 PF03811.8 AAS54010.1 - 0.15 11.6 1.6 0.33 10.4 0.1 2.1 2 0 0 2 2 2 0 InsA N-terminal domain tRNA-synt_1e PF01406.14 AAS54011.2 - 1.5e-131 438.0 0.0 2e-131 437.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 AAS54011.2 - 5.5e-08 31.8 0.4 1.5e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AAS54011.2 - 9.3e-06 23.9 0.0 2.3e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.16 AAS54011.2 - 0.00062 18.5 0.6 0.019 13.6 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.13 AAS54011.2 - 0.043 12.4 0.0 0.16 10.6 0.0 1.9 3 0 0 3 3 3 0 tRNA synthetases class I (K) NAP PF00956.13 AAS54012.1 - 6e-15 55.0 2.8 3.5e-10 39.4 0.0 2.3 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) SUI1 PF01253.17 AAS54013.2 - 7.9e-29 99.3 0.4 9.5e-29 99.0 0.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2575 PF10837.3 AAS54013.2 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) Cas_Csa5 PF09702.5 AAS54013.2 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) Homeobox PF00046.24 AAS54014.3 - 2.3e-16 59.1 1.9 2.9e-16 58.8 1.3 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 AAS54014.3 - 1.5e-05 24.5 0.8 2.3e-05 23.9 0.2 1.5 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.1 AAS54014.3 - 0.18 11.5 0.6 0.4 10.3 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain HMG_box PF00505.14 AAS54015.3 - 0.12 12.6 1.7 2.2 8.6 1.2 2.3 1 1 0 1 1 1 0 HMG (high mobility group) box Sec10 PF07393.6 AAS54016.3 - 2.1e-58 198.1 1.7 2.8e-58 197.7 1.2 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 NAD_Gly3P_dh_C PF07479.9 AAS54016.3 - 0.022 14.4 0.0 2.1 8.0 0.0 3.1 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus PRP21_like_P PF12230.3 AAS54017.2 - 2.7e-35 121.9 14.5 8.4e-24 84.3 4.3 2.8 2 1 1 3 3 3 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 AAS54017.2 - 4.4e-07 29.4 0.2 4.4e-07 29.4 0.1 2.2 2 0 0 2 2 2 1 Surp module zf-CCHC PF00098.18 AAS54018.1 - 2.6e-47 156.5 49.7 2.1e-08 33.7 0.6 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 AAS54018.1 - 7e-09 35.2 45.3 0.015 14.9 0.4 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 AAS54018.1 - 0.012 15.3 42.4 4.8 7.0 0.4 7.1 2 2 4 6 6 6 0 Zinc knuckle zf-CCHC_2 PF13696.1 AAS54018.1 - 0.049 13.1 0.4 0.049 13.1 0.3 7.0 2 2 5 7 7 7 0 Zinc knuckle Pterin_bind PF00809.17 AAS54019.2 - 2.2e-47 161.1 0.0 9.5e-46 155.8 0.0 2.6 2 1 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 AAS54019.2 - 2.7e-39 133.8 0.0 4.8e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 AAS54019.2 - 4.3e-30 104.1 0.0 1.1e-13 51.3 0.0 2.7 3 0 0 3 3 3 2 Dihydroneopterin aldolase DUF1010 PF06231.6 AAS54019.2 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) FAD_binding_3 PF01494.14 AAS54020.1 - 2.3e-20 72.9 0.9 2.5e-09 36.6 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Lycopene_cycl PF05834.7 AAS54020.1 - 1.4e-05 24.1 0.1 0.034 13.0 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 AAS54020.1 - 0.00072 18.5 0.0 0.29 9.9 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 AAS54020.1 - 0.0089 14.7 0.0 0.05 12.2 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 AAS54020.1 - 0.029 14.7 0.0 5.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AAS54020.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 AAS54020.1 - 0.039 13.8 0.1 0.078 12.8 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AAS54020.1 - 0.051 13.3 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 AAS54020.1 - 0.062 12.1 0.1 0.098 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain SE PF08491.5 AAS54020.1 - 0.073 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_8 PF13450.1 AAS54020.1 - 0.093 12.7 0.1 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain RRM_1 PF00076.17 AAS54021.1 - 7.4e-15 54.3 0.0 1.2e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS54021.1 - 4.5e-14 52.1 0.0 7.9e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS54021.1 - 1.2e-10 41.1 0.0 2.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 AAS54021.1 - 9.4e-10 38.9 0.0 1.3e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PGAP1 PF07819.8 AAS54022.1 - 8.5e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 AAS54022.1 - 1.1e-05 25.1 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 AAS54022.1 - 1.2e-05 24.7 0.0 2.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 AAS54022.1 - 8.1e-05 22.6 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 AAS54022.1 - 0.00031 19.9 0.0 0.0022 17.1 0.0 2.2 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 AAS54022.1 - 0.0046 15.9 0.0 0.0058 15.6 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 AAS54022.1 - 0.0099 15.6 0.0 0.045 13.5 0.0 2.0 2 1 1 3 3 3 1 Alpha/beta hydrolase family PH PF00169.24 AAS54023.1 - 3.5e-05 23.9 0.4 0.00032 20.8 0.0 2.9 4 0 0 4 4 4 1 PH domain Dsl1_C PF11989.3 AAS54024.1 - 4.1e-132 439.7 17.9 4.1e-132 439.7 12.4 2.2 3 0 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal Dsl1_N PF11988.3 AAS54024.1 - 1.3e-129 432.1 7.5 1.3e-129 432.1 5.2 1.7 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 N terminal HMA PF00403.21 AAS54025.1 - 4.9e-10 39.3 0.2 5.8e-10 39.1 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF1364 PF07102.7 AAS54025.1 - 0.0031 17.3 0.1 0.0047 16.7 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1364) DUF1216 PF06746.6 AAS54025.1 - 0.019 14.7 0.1 0.02 14.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) Yae1_N PF09811.4 AAS54026.1 - 1.1e-10 40.8 2.2 1.1e-10 40.8 1.5 1.9 2 0 0 2 2 2 1 Essential protein Yae1, N terminal GYF PF02213.11 AAS54027.2 - 3.6e-12 45.6 3.7 3.6e-12 45.6 2.6 1.9 2 0 0 2 2 2 1 GYF domain ORC5_C PF14630.1 AAS54028.1 - 1.5e-65 221.3 0.9 2e-65 220.9 0.6 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 AAS54028.1 - 6.6e-11 42.5 0.1 2.6e-10 40.5 0.0 2.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 AAS54028.1 - 0.00024 21.2 0.0 0.00069 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AAS54028.1 - 0.0018 18.1 1.0 0.024 14.5 0.2 2.7 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 AAS54028.1 - 0.0026 17.4 0.0 0.0071 16.0 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase DUF1744 PF08490.7 AAS54029.2 - 4.2e-151 503.0 1.1 7.6e-151 502.1 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 AAS54029.2 - 2.6e-66 223.7 1.8 2.6e-66 223.7 1.2 1.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 AAS54029.2 - 5.8e-23 81.4 1.4 2.5e-22 79.3 1.4 1.7 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 AAS54029.2 - 8.9e-08 31.9 0.8 6.1e-07 29.1 0.2 2.7 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Phos_pyr_kin PF08543.7 AAS54029.2 - 0.43 9.7 0.1 0.82 8.8 0.1 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase YIF1 PF03878.10 AAS54030.1 - 6.1e-71 238.3 7.2 8.1e-71 237.9 5.0 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 AAS54030.1 - 1.1e-05 25.0 0.7 1.1e-05 25.0 0.5 1.6 2 0 0 2 2 2 1 Yip1 domain DnaJ PF00226.26 AAS54031.1 - 8.3e-16 57.4 0.5 1.6e-15 56.5 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain CRAL_TRIO PF00650.15 AAS54032.1 - 1.5e-35 121.9 0.0 2.5e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AAS54032.1 - 1.9e-13 50.3 1.8 4.4e-13 49.1 0.8 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AAS54032.1 - 0.0066 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain UBA_4 PF14555.1 AAS54032.1 - 0.03 13.8 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain UBA PF00627.26 AAS54032.1 - 0.03 14.1 0.1 0.066 13.0 0.1 1.5 1 0 0 1 1 1 0 UBA/TS-N domain DUF2422 PF10337.4 AAS54033.1 - 4.6e-43 147.6 2.3 4.6e-43 147.6 1.6 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 AAS54033.1 - 1.1e-11 44.7 13.3 1.1e-11 44.7 9.2 2.9 2 2 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 AAS54033.1 - 5.8e-07 28.5 10.3 1.3e-05 24.0 0.6 2.6 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 AAS54033.1 - 0.078 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) UFD1 PF03152.9 AAS54034.1 - 1e-72 242.9 0.0 1.3e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 TPR_16 PF13432.1 AAS54035.2 - 5.4e-21 74.7 0.4 0.0004 20.9 0.0 7.7 8 1 1 9 9 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 AAS54035.2 - 1e-20 73.1 13.3 4.1e-05 23.1 0.0 8.0 4 3 3 8 8 8 6 TPR repeat TPR_12 PF13424.1 AAS54035.2 - 4.7e-18 64.9 3.1 5.6e-05 22.9 0.0 6.6 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 AAS54035.2 - 3.4e-16 57.7 9.1 0.15 12.0 0.0 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 AAS54035.2 - 2.5e-14 53.3 1.5 0.0013 19.0 0.0 7.2 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 AAS54035.2 - 8.5e-13 47.3 12.0 0.061 12.9 0.0 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 AAS54035.2 - 3.3e-12 45.5 5.8 0.042 14.0 0.3 7.9 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 AAS54035.2 - 1.8e-11 43.5 0.1 2.6 8.9 0.0 8.5 5 3 6 11 11 10 3 Tetratricopeptide repeat TPR_6 PF13174.1 AAS54035.2 - 4.9e-09 36.0 3.6 0.015 15.7 0.0 7.3 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 AAS54035.2 - 1.5e-07 30.6 12.2 0.27 11.1 0.0 8.5 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_15 PF13429.1 AAS54035.2 - 6e-07 28.8 1.3 0.41 9.6 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 AAS54035.2 - 7.7e-06 25.6 0.0 0.22 11.3 0.0 4.6 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 AAS54035.2 - 2.4e-05 23.7 3.2 3.6 7.6 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 AAS54035.2 - 0.00022 21.2 1.2 2.6 8.2 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 AAS54035.2 - 0.01 16.0 1.1 0.35 11.0 0.0 2.9 3 0 0 3 3 2 0 Alkyl sulfatase dimerisation TPPII_N PF12583.3 AAS54035.2 - 9.1 6.4 8.4 12 5.9 0.0 3.6 4 0 0 4 4 4 0 Tripeptidyl peptidase II N terminal Ist1 PF03398.9 AAS54036.2 - 4.9e-59 198.4 2.1 4.9e-59 198.4 1.5 1.8 2 0 0 2 2 2 1 Regulator of Vps4 activity in the MVB pathway Mmp37 PF09139.6 AAS54037.2 - 1.5e-106 356.1 5.4 5.6e-96 321.4 0.5 2.1 1 1 0 2 2 2 2 Mitochondrial matrix Mmp37 PI3_PI4_kinase PF00454.22 AAS54038.2 - 3.3e-30 105.2 0.1 7.3e-30 104.1 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 AAS54038.2 - 5.3e-21 74.1 3.2 5.9e-21 73.9 0.7 2.3 2 0 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 AAS54038.2 - 3.1e-05 23.2 1.6 4.3e-05 22.7 0.2 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) AA_permease PF00324.16 AAS54039.2 - 2.2e-131 438.4 42.5 2.7e-131 438.2 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS54039.2 - 6.1e-36 123.8 44.7 9.4e-36 123.2 31.0 1.3 1 0 0 1 1 1 1 Amino acid permease RhodobacterPufX PF11511.3 AAS54039.2 - 0.061 12.7 1.5 4.3 6.8 0.2 3.1 2 0 0 2 2 2 0 Intrinsic membrane protein PufX AA_permease PF00324.16 AAS54040.1 - 4.9e-132 440.6 47.9 5.9e-132 440.3 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS54040.1 - 1.9e-31 109.0 54.2 6e-31 107.4 37.4 1.7 1 1 0 1 1 1 1 Amino acid permease DUF2101 PF09874.4 AAS54040.1 - 0.0021 17.6 1.7 0.0021 17.6 1.2 2.3 2 0 0 2 2 2 1 Predicted membrane protein (DUF2101) Peptidase_M50 PF02163.17 AAS54040.1 - 0.018 14.0 0.2 2.5 7.0 2.4 2.5 2 1 0 2 2 2 0 Peptidase family M50 FH2 PF02181.18 AAS54041.2 - 5.1e-84 282.2 11.1 5.1e-84 282.2 7.7 2.8 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 AAS54041.2 - 2.5e-51 173.9 0.2 5.5e-47 159.7 0.0 3.2 2 0 0 2 2 2 2 Diaphanous FH3 Domain Drf_GBD PF06371.8 AAS54041.2 - 1.5e-31 109.2 2.4 2e-31 108.8 0.2 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Sec2p PF06428.6 AAS54042.1 - 2.9e-28 97.6 13.8 2.9e-28 97.6 9.6 3.5 1 1 2 3 3 3 1 GDP/GTP exchange factor Sec2p IFT20 PF14931.1 AAS54042.1 - 5 7.0 26.2 2.8 7.8 8.8 2.7 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Aa_trans PF01490.13 AAS54043.2 - 1.3e-83 280.8 25.5 1.5e-83 280.5 17.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2427 PF10348.4 AAS54043.2 - 0.26 10.8 4.5 2.5 7.6 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) TIMELESS PF04821.9 AAS54044.2 - 4.6e-48 163.7 0.2 4.6e-48 163.7 0.1 2.5 2 1 0 2 2 2 1 Timeless protein Sad1_UNC PF07738.8 AAS54045.1 - 7.2e-34 116.4 0.1 1.5e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal PPP5 PF08321.7 AAS54045.1 - 0.42 10.6 5.2 8.7 6.4 0.6 3.0 3 0 0 3 3 3 0 PPP5 TPR repeat region Peptidase_M1 PF01433.15 AAS54046.1 - 3.1e-09 36.4 0.4 0.00033 19.8 0.0 2.7 3 0 0 3 3 3 2 Peptidase family M1 Mso1_Sec1_bdg PF14475.1 AAS54046.1 - 0.029 13.7 0.0 0.069 12.5 0.0 1.6 1 0 0 1 1 1 0 Sec1-binding region of Mso1 2-Hacid_dh_C PF02826.14 AAS54047.1 - 1.8e-56 190.0 0.0 3.6e-56 189.1 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AAS54047.1 - 4.1e-13 48.9 0.0 5.1e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AAS54047.1 - 0.0012 18.6 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 AAS54047.1 - 0.002 18.2 0.0 0.0047 17.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 AAS54047.1 - 0.0053 16.1 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 AAS54047.1 - 0.053 13.3 0.0 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ThiF PF00899.16 AAS54047.1 - 0.06 13.1 0.0 0.16 11.8 0.1 1.7 2 0 0 2 2 2 0 ThiF family DUF1345 PF07077.6 AAS54048.2 - 0.023 14.2 1.5 0.052 13.0 1.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) GpcrRhopsn4 PF10192.4 AAS54048.2 - 0.032 13.4 0.4 0.038 13.1 0.3 1.1 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain HCO3_cotransp PF00955.16 AAS54049.2 - 1e-53 182.8 8.4 2.3e-35 122.2 1.3 2.1 1 1 1 2 2 2 2 HCO3- transporter family Per1 PF04080.8 AAS54050.2 - 3.9e-99 331.4 2.4 4.7e-99 331.1 1.7 1.1 1 0 0 1 1 1 1 Per1-like Spindle_Spc25 PF08234.7 AAS54051.1 - 3.7e-18 65.3 0.0 6.1e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF3584 PF12128.3 AAS54051.1 - 0.00047 17.6 15.3 0.00051 17.5 10.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) APG6 PF04111.7 AAS54051.1 - 0.00063 18.8 13.1 0.00085 18.4 9.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 CALCOCO1 PF07888.6 AAS54051.1 - 0.00064 18.1 6.3 0.00075 17.9 4.4 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like CCDC155 PF14662.1 AAS54051.1 - 0.0019 17.8 17.2 0.0027 17.3 11.9 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 ATG16 PF08614.6 AAS54051.1 - 0.0095 15.7 20.4 0.012 15.4 4.6 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) GAS PF13851.1 AAS54051.1 - 0.014 14.5 10.2 0.02 14.1 7.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Filament PF00038.16 AAS54051.1 - 0.021 14.2 13.9 0.042 13.3 9.6 1.5 1 0 0 1 1 1 0 Intermediate filament protein Exonuc_VII_L PF02601.10 AAS54051.1 - 0.068 12.3 6.0 0.086 12.0 4.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.8 AAS54051.1 - 0.073 11.4 5.0 0.098 11.0 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2353 PF09789.4 AAS54051.1 - 0.089 12.0 11.7 0.12 11.5 8.1 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) TPR_MLP1_2 PF07926.7 AAS54051.1 - 0.09 12.5 17.2 0.13 12.0 12.0 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 AAS54051.1 - 0.17 10.5 6.9 0.23 10.0 4.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3867 PF12983.2 AAS54051.1 - 0.18 11.7 0.0 0.23 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) Jnk-SapK_ap_N PF09744.4 AAS54051.1 - 0.18 11.7 13.8 0.039 13.9 2.5 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.14 AAS54051.1 - 0.19 9.5 4.8 0.22 9.3 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 AAS54051.1 - 0.34 9.8 13.2 0.46 9.3 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bacillus_HBL PF05791.6 AAS54051.1 - 0.38 10.0 5.6 0.52 9.6 3.1 1.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Atg14 PF10186.4 AAS54051.1 - 0.4 9.5 16.6 0.71 8.7 11.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Borrelia_P83 PF05262.6 AAS54051.1 - 0.4 8.8 6.4 0.5 8.5 4.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein HALZ PF02183.13 AAS54051.1 - 0.61 9.8 13.0 4.3 7.1 0.6 3.8 3 1 1 4 4 4 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 AAS54051.1 - 0.66 9.7 3.1 1.9 8.2 0.4 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mnd1 PF03962.10 AAS54051.1 - 0.71 9.4 17.7 1.2 8.7 11.6 1.8 1 1 1 2 2 2 0 Mnd1 family HrpB7 PF09486.5 AAS54051.1 - 0.79 9.6 25.7 5.6 6.8 7.2 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Rab5-bind PF09311.6 AAS54051.1 - 0.85 9.4 24.1 0.94 9.3 15.3 1.9 1 1 0 1 1 1 0 Rabaptin-like protein TSC22 PF01166.13 AAS54051.1 - 0.89 9.5 4.9 0.23 11.4 0.7 2.0 2 0 0 2 2 1 0 TSC-22/dip/bun family DUF972 PF06156.8 AAS54051.1 - 0.93 9.8 13.5 0.44 10.9 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Peptidase_S46 PF10459.4 AAS54051.1 - 0.95 7.7 10.6 1.2 7.4 7.4 1.0 1 0 0 1 1 1 0 Peptidase S46 SNAPc19 PF15497.1 AAS54051.1 - 1.5 9.0 7.9 2.8 8.1 5.5 1.6 1 1 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 TMF_DNA_bd PF12329.3 AAS54051.1 - 2.1 8.2 13.6 0.58 9.9 1.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding IFT20 PF14931.1 AAS54051.1 - 2.1 8.2 12.4 11 6.0 1.2 2.3 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 IncA PF04156.9 AAS54051.1 - 2.1 7.9 18.6 3.2 7.3 12.9 1.3 1 0 0 1 1 1 0 IncA protein Cortex-I_coil PF09304.5 AAS54051.1 - 5.3 7.1 16.6 1.5 8.8 8.6 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil DivIVA PF05103.8 AAS54051.1 - 5.7 7.0 13.5 8.7 6.4 9.4 1.3 1 0 0 1 1 1 0 DivIVA protein TBPIP PF07106.8 AAS54051.1 - 6.3 6.3 9.5 12 5.3 6.6 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4200 PF13863.1 AAS54051.1 - 7.6 6.5 20.9 14 5.6 14.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Exo_endo_phos PF03372.18 AAS54052.1 - 5.4e-18 65.8 0.4 7.7e-18 65.3 0.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_transf_28 PF03033.15 AAS54053.2 - 1.2e-25 89.8 0.0 2.6e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 AAS54053.2 - 9.6e-25 85.8 4.4 7.5e-16 57.4 0.1 3.8 4 0 0 4 4 4 2 GRAM domain PH PF00169.24 AAS54053.2 - 1.7e-09 37.8 2.7 7.3e-09 35.7 1.1 2.7 2 1 1 3 3 3 1 PH domain UDPGT PF00201.13 AAS54053.2 - 4.1e-08 32.2 0.1 9.8e-08 30.9 0.1 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.1 AAS54053.2 - 0.089 12.6 0.2 0.24 11.2 0.2 1.7 1 0 0 1 1 1 0 PH domain PH_11 PF15413.1 AAS54053.2 - 0.11 12.7 0.6 0.52 10.5 0.4 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Abhydrolase_1 PF00561.15 AAS54054.1 - 7.2e-55 186.0 0.0 1.2e-54 185.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AAS54054.1 - 1.1e-13 51.5 0.9 8.7e-13 48.6 0.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AAS54054.1 - 5.3e-05 23.0 0.0 0.0022 17.7 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 AAS54054.1 - 0.057 12.8 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Putative esterase ABC_membrane PF00664.18 AAS54055.1 - 4e-56 190.4 1.0 5e-56 190.1 0.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 AAS54055.1 - 1.2e-29 103.3 0.0 3.3e-29 101.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 AAS54055.1 - 2.4e-07 30.2 0.1 2e-05 23.9 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AAS54055.1 - 0.00037 20.5 0.1 0.2 11.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AAS54055.1 - 0.0015 18.5 0.9 0.0083 16.1 0.6 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 AAS54055.1 - 0.0017 19.1 0.0 0.0035 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AAS54055.1 - 0.0032 17.7 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AAS54055.1 - 0.0038 17.3 0.4 0.072 13.2 0.2 2.9 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 AAS54055.1 - 0.018 14.7 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 AAS54055.1 - 0.033 14.3 0.5 0.94 9.6 0.4 2.8 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 AAS54055.1 - 0.035 12.7 0.0 0.082 11.4 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.1 AAS54055.1 - 0.04 13.3 0.0 0.44 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 AAS54055.1 - 0.043 13.2 0.1 0.57 9.5 0.0 2.8 4 0 0 4 4 4 0 AAA-like domain SbcCD_C PF13558.1 AAS54055.1 - 0.048 13.5 1.8 0.21 11.5 0.3 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.24 AAS54055.1 - 0.053 13.0 0.0 13 5.2 0.0 2.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF87 PF01935.12 AAS54055.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_29 PF13555.1 AAS54055.1 - 0.061 12.8 0.0 0.22 11.0 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 AAS54055.1 - 0.067 13.0 0.1 2 8.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 AAS54055.1 - 0.11 12.3 0.1 7.8 6.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain PH PF00169.24 AAS54056.2 - 9.2e-06 25.8 0.0 0.0024 18.0 0.0 2.6 2 0 0 2 2 2 2 PH domain EMG1 PF03587.9 AAS54058.1 - 3.3e-76 255.1 0.0 3.9e-76 254.8 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase LCD1 PF09798.4 AAS54059.1 - 2.1e-259 861.9 12.7 2.5e-259 861.7 8.8 1.0 1 0 0 1 1 1 1 DNA damage checkpoint protein Exonuc_VII_L PF02601.10 AAS54059.1 - 0.051 12.7 2.2 4 6.5 2.7 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Macoilin PF09726.4 AAS54059.1 - 0.7 8.0 6.1 0.97 7.6 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_L37e PF01907.14 AAS54060.1 - 1.2e-28 98.5 11.7 2e-28 97.9 8.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 AAS54060.1 - 0.00058 19.6 1.6 0.00089 19.0 1.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 AAS54060.1 - 0.0098 15.5 0.2 0.011 15.4 0.1 1.2 1 0 0 1 1 1 1 SelR domain zinc_ribbon_6 PF14599.1 AAS54060.1 - 0.041 13.6 1.9 0.06 13.1 1.3 1.2 1 0 0 1 1 1 0 Zinc-ribbon C1_1 PF00130.17 AAS54060.1 - 0.041 13.5 2.5 0.066 12.9 1.8 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GATA PF00320.22 AAS54060.1 - 0.16 11.3 6.2 0.56 9.5 1.0 2.4 1 1 1 2 2 2 0 GATA zinc finger zinc_ribbon_2 PF13240.1 AAS54060.1 - 0.38 10.2 4.4 2.3 7.8 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 AAS54060.1 - 0.42 9.8 4.6 3.2 7.0 3.2 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.20 AAS54060.1 - 2 8.1 5.6 3.2 7.4 3.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HYPF PF07503.7 AAS54060.1 - 2.7 7.5 6.1 3.4 7.1 1.9 2.1 1 1 1 2 2 2 0 HypF finger FHA PF00498.21 AAS54061.1 - 5e-06 26.5 0.1 2.1e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 FHA domain Erp_C PF06780.6 AAS54061.1 - 0.045 13.6 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 Erp protein C-terminus Ank PF00023.25 AAS54062.2 - 2.5e-12 45.9 0.8 1.2e-06 28.0 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 AAS54062.2 - 2.7e-11 43.3 0.4 2.3e-07 30.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 AAS54062.2 - 4.8e-11 42.8 0.0 5.3e-05 23.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AAS54062.2 - 6.2e-10 38.3 0.9 2.7e-05 23.9 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 AAS54062.2 - 2.5e-08 34.2 0.3 0.00087 19.7 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) SPX PF03105.14 AAS54062.2 - 0.0039 17.0 0.2 2.2 8.0 2.7 2.1 1 1 0 2 2 2 1 SPX domain DUF3287 PF11690.3 AAS54062.2 - 0.036 14.1 0.9 4.7 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Phage_GP20 PF06810.6 AAS54062.2 - 0.089 12.2 11.1 1.4 8.3 0.8 2.8 2 1 1 3 3 3 0 Phage minor structural protein GP20 IncA PF04156.9 AAS54062.2 - 0.15 11.6 9.4 0.34 10.4 1.9 2.3 2 0 0 2 2 2 0 IncA protein THOC7 PF05615.8 AAS54062.2 - 1 9.6 10.1 0.91 9.7 3.9 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 Nup54 PF13874.1 AAS54062.2 - 1.3 8.6 7.1 19 4.9 0.0 2.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DivIVA PF05103.8 AAS54062.2 - 1.6 8.7 7.9 0.75 9.8 2.6 2.2 2 0 0 2 2 2 0 DivIVA protein ADIP PF11559.3 AAS54062.2 - 1.7 8.5 14.0 0.053 13.4 0.5 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.7 AAS54062.2 - 2.9 7.7 7.1 1.2 8.9 0.9 2.7 3 1 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 AAS54062.2 - 3.5 7.1 8.8 8 5.9 3.1 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 AAS54062.2 - 5.6 7.0 10.2 7.5 6.6 3.8 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NAP PF00956.13 AAS54062.2 - 7.7 5.5 8.3 0.55 9.3 0.9 2.3 3 0 0 3 3 3 0 Nucleosome assembly protein (NAP) OmpH PF03938.9 AAS54062.2 - 9.5 6.1 15.7 1.4 8.8 5.6 2.3 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF605 PF04652.11 AAS54063.1 - 1.4e-48 166.2 5.5 2.3e-32 112.8 0.0 2.0 1 1 1 2 2 2 2 Vta1 like S-AdoMet_synt_C PF02773.11 AAS54064.1 - 2.7e-74 247.4 0.1 4.3e-74 246.7 0.1 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 AAS54064.1 - 1.2e-45 154.3 0.0 2.8e-45 153.1 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 AAS54064.1 - 4.4e-44 148.7 0.1 7.9e-44 147.9 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain PAP2 PF01569.16 AAS54065.1 - 2.3e-19 69.3 1.8 1e-18 67.2 0.9 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 AAS54065.1 - 0.003 17.7 0.5 0.019 15.2 0.1 2.2 2 0 0 2 2 2 1 PAP2 superfamily C-terminal DUF4131 PF13567.1 AAS54065.1 - 2.9 7.2 10.9 0.31 10.4 2.7 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) PBP PF01161.15 AAS54066.1 - 6.1e-29 100.7 0.0 7.7e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PSP1 PF04468.7 AAS54067.1 - 8.9e-36 121.7 0.0 1.6e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Pkinase PF00069.20 AAS54068.1 - 2.6e-73 246.4 3.8 1.6e-72 243.7 0.0 3.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS54068.1 - 9.7e-36 123.1 0.0 2.4e-35 121.8 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS54068.1 - 1.1e-07 31.0 0.0 1.1e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 AAS54068.1 - 0.22 11.2 2.9 0.4 10.3 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Rad60-SLD PF11976.3 AAS54069.1 - 1.1e-21 76.3 0.1 1.6e-21 75.7 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 AAS54069.1 - 1.3e-11 43.7 0.0 1.6e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family AA_permease PF00324.16 AAS54070.1 - 1.7e-125 419.0 33.3 2e-125 418.8 23.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS54070.1 - 2.3e-28 98.8 33.5 2.9e-28 98.5 23.2 1.1 1 0 0 1 1 1 1 Amino acid permease SH3_9 PF14604.1 AAS54071.1 - 4.3e-06 26.2 0.0 4.1e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 AAS54071.1 - 0.017 14.4 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 SH3 domain CAP PF00188.21 AAS54072.1 - 1.7e-19 70.5 2.1 1.7e-19 70.5 1.5 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family CAP_GLY PF01302.20 AAS54074.2 - 2.8e-16 58.9 0.8 5e-16 58.1 0.2 1.7 2 0 0 2 2 2 1 CAP-Gly domain Reo_sigmaC PF04582.7 AAS54074.2 - 0.21 10.7 2.4 3.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 AAS54074.2 - 3.8 6.6 35.8 8.3 5.5 6.0 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 AAS54074.2 - 6.5 6.6 35.0 1.2 9.0 7.3 3.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Histidinol_dh PF00815.15 AAS54075.2 - 7.8e-179 594.5 4.1 1e-178 594.2 2.8 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 AAS54075.2 - 6.3e-28 96.2 0.0 1.2e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 AAS54075.2 - 2.4e-10 40.5 0.5 2.4e-10 40.5 0.3 1.9 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 AAS54075.2 - 0.0065 16.3 0.2 0.015 15.2 0.2 1.6 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Complex1_LYR PF05347.10 AAS54076.1 - 3.8e-13 49.0 0.2 2.4e-11 43.2 0.0 2.4 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AAS54076.1 - 4.5e-11 42.7 0.0 8.5e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 AAS54076.1 - 1.3e-05 25.6 0.0 1.9e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Complex1_LYR-like PMT_C PF11647.3 AAS54076.1 - 0.054 13.1 0.0 7.1 6.3 0.0 2.3 2 0 0 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 RRP7 PF12923.2 AAS54077.2 - 2e-33 115.2 6.0 3.4e-33 114.4 4.2 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) Adenyl_cycl_N PF12633.2 AAS54077.2 - 0.026 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase NT domain RRM_6 PF14259.1 AAS54077.2 - 0.046 13.6 0.2 4.9 7.2 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF223 PF02721.9 AAS54077.2 - 0.12 12.4 0.8 0.34 11.0 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function DUF223 Bclt PF15318.1 AAS54077.2 - 2 8.4 5.4 2.7 7.9 2.8 1.8 2 0 0 2 2 2 0 Putative Bcl-2 like protein of testis RA PF00788.18 AAS54078.1 - 6.2e-16 58.6 0.0 1.2e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ste50p-SAM PF09235.5 AAS54078.1 - 2.4e-13 49.8 0.2 1.2e-09 38.0 0.0 2.4 2 0 0 2 2 2 2 Ste50p, sterile alpha motif SAM_2 PF07647.12 AAS54078.1 - 0.0017 18.1 0.6 0.0099 15.7 0.0 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 AAS54078.1 - 0.18 11.9 1.3 0.71 10.0 0.0 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Totivirus_coat PF05518.6 AAS54078.1 - 8.6 4.0 8.8 12 3.5 6.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein DUF3128 PF11326.3 AAS54079.1 - 9.5e-28 96.1 0.5 1.1e-27 95.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Adeno_VII PF03228.9 AAS54079.1 - 0.019 15.5 0.2 0.1 13.1 0.0 1.9 2 0 0 2 2 2 0 Adenoviral core protein VII SelR PF01641.13 AAS54080.1 - 1.8e-48 163.3 0.0 2.1e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 SelR domain LZ_Tnp_IS481 PF13011.1 AAS54080.1 - 0.042 14.1 0.2 0.11 12.8 0.1 1.7 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 DZR PF12773.2 AAS54080.1 - 0.054 13.3 0.0 0.14 11.9 0.0 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-Mss51 PF13824.1 AAS54080.1 - 0.46 10.3 2.7 3.6 7.5 0.2 2.8 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-LSD1 PF06943.7 AAS54080.1 - 3.2 7.4 6.1 22 4.7 0.8 3.1 2 1 0 2 2 2 0 LSD1 zinc finger GAT PF03127.9 AAS54081.1 - 2.4e-05 24.2 0.4 6.5e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 GAT domain PG_binding_4 PF12229.3 AAS54081.1 - 0.019 15.2 0.1 0.04 14.1 0.1 1.5 1 0 0 1 1 1 0 Putative peptidoglycan binding domain VHS PF00790.14 AAS54081.1 - 0.038 13.6 0.1 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 VHS domain Glutaredoxin PF00462.19 AAS54082.1 - 2.8e-17 62.4 0.0 4.1e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 AAS54082.1 - 0.0013 18.8 0.0 0.0019 18.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_7 PF13899.1 AAS54082.1 - 0.0019 18.1 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 AAS54082.1 - 0.013 15.2 0.2 0.22 11.3 0.2 2.3 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.1 AAS54082.1 - 0.03 14.3 0.2 0.56 10.1 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Tox-PL-2 PF15643.1 AAS54082.1 - 0.044 13.7 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Papain fold toxin 2 DSBA PF01323.15 AAS54082.1 - 0.1 12.1 0.0 3.5 7.1 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Flocculin_t3 PF13928.1 AAS54083.1 - 1.2e-09 38.1 16.5 2.1e-06 27.7 2.6 7.1 4 2 1 5 5 5 2 Flocculin type 3 repeat La PF05383.12 AAS54085.1 - 5.5e-19 67.7 0.1 1.5e-18 66.3 0.0 1.7 2 0 0 2 2 2 1 La domain ATG22 PF11700.3 AAS54086.1 - 1.1e-163 545.1 22.5 1.3e-163 544.9 15.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like WD40 PF00400.27 AAS54087.1 - 6.8e-20 70.1 12.6 2.8e-05 23.8 0.1 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 AAS54087.1 - 0.0013 18.4 0.3 0.39 10.3 0.0 3.2 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A BBS2_N PF14781.1 AAS54087.1 - 0.011 15.3 0.0 5.6 6.5 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal DUF2647 PF10839.3 AAS54087.1 - 0.093 12.8 0.0 0.6 10.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2647) Kelch_2 PF07646.10 AAS54087.1 - 0.11 12.3 0.3 0.48 10.2 0.2 2.1 1 0 0 1 1 1 0 Kelch motif Hexokinase_2 PF03727.11 AAS54088.2 - 5.4e-87 291.0 0.0 7e-87 290.6 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 AAS54088.2 - 1e-71 240.5 0.0 2.1e-71 239.5 0.0 1.5 1 0 0 1 1 1 1 Hexokinase GRASP55_65 PF04495.9 AAS54089.1 - 1.7e-33 115.5 0.0 1.1e-31 109.6 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Thioredoxin PF00085.15 AAS54090.2 - 1.3e-54 182.2 0.0 5.6e-27 93.4 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 AAS54090.2 - 5.1e-26 91.5 0.1 2.5e-21 76.3 0.0 4.1 3 2 1 4 4 4 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 AAS54090.2 - 1.1e-09 38.4 3.9 0.0019 18.4 0.5 4.1 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 AAS54090.2 - 2.1e-08 34.0 0.1 0.00069 19.5 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 AAS54090.2 - 3.6e-08 33.1 0.6 0.0019 17.8 0.0 3.5 3 1 1 4 4 4 2 AhpC/TSA family Thioredoxin_8 PF13905.1 AAS54090.2 - 6.6e-07 29.3 0.0 0.017 15.2 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.5 AAS54090.2 - 1.2e-05 24.8 0.3 0.016 14.7 0.0 2.8 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 AAS54090.2 - 0.0063 16.0 0.1 1.8 8.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_4 PF13462.1 AAS54090.2 - 0.0089 16.0 0.2 4.1 7.3 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin DUF1539 PF07560.6 AAS54090.2 - 0.03 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Mgr1 PF08602.5 AAS54091.1 - 1.5e-154 514.3 0.0 1.8e-154 514.1 0.0 1.0 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit DUF1620 PF07774.8 AAS54092.1 - 6.5e-73 244.5 1.5 1.3e-72 243.5 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ PF01011.16 AAS54092.1 - 0.0024 17.2 0.0 0.0073 15.7 0.0 1.8 1 0 0 1 1 1 1 PQQ enzyme repeat PQQ_2 PF13360.1 AAS54092.1 - 0.12 11.7 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain CTP_transf_2 PF01467.21 AAS54093.1 - 1.5e-06 28.3 0.0 3.5e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase HVSL PF09749.4 AAS54093.1 - 0.02 13.9 0.1 0.18 10.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein ATP-sulfurylase PF01747.12 AAS54093.1 - 0.098 11.9 0.0 0.28 10.4 0.0 1.7 2 0 0 2 2 2 0 ATP-sulfurylase Zn_clus PF00172.13 AAS54094.2 - 3.8e-06 26.6 7.2 7.3e-06 25.8 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Recep_L_domain PF01030.19 AAS54095.1 - 9.1e-09 35.2 7.5 0.0083 16.0 0.0 4.2 2 1 2 4 4 4 4 Receptor L domain LRR_4 PF12799.2 AAS54095.1 - 0.12 12.0 10.3 3.9 7.1 2.3 4.0 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Pkinase PF00069.20 AAS54096.1 - 2.4e-68 230.1 0.0 3.1e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS54096.1 - 1.3e-46 158.7 0.0 1.9e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS54096.1 - 1e-05 24.7 0.0 0.00011 21.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF4404 PF14357.1 AAS54096.1 - 0.035 14.5 0.2 0.074 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) ArfGap PF01412.13 AAS54097.1 - 4.9e-31 106.9 1.5 1.4e-30 105.4 1.0 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 AAS54097.1 - 1.9e-14 53.7 8.2 5.3e-14 52.2 0.1 3.8 4 1 0 4 4 4 1 PH domain PH_9 PF15410.1 AAS54097.1 - 0.0035 17.4 0.2 0.014 15.5 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Pmp3 PF01679.12 AAS54098.1 - 4.2e-16 58.3 2.0 5.9e-16 57.8 1.4 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RPAP1_C PF08620.5 AAS54099.2 - 3.4e-32 110.1 0.1 5.7e-32 109.4 0.1 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 AAS54099.2 - 6.2e-16 57.7 0.7 1.5e-15 56.4 0.5 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal HEAT PF02985.17 AAS54099.2 - 0.0078 16.2 0.0 0.05 13.7 0.0 2.4 2 0 0 2 2 2 1 HEAT repeat ALMT PF11744.3 AAS54100.2 - 0.11 11.1 1.0 0.15 10.7 0.3 1.4 1 1 0 1 1 1 0 Aluminium activated malate transporter DUF3782 PF12644.2 AAS54100.2 - 1.4 8.8 4.4 58 3.5 0.3 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3782) Fumble PF03630.9 AAS54101.2 - 5.6e-123 410.1 2.1 1.6e-120 402.0 1.5 2.0 1 1 0 1 1 1 1 Fumble T4SS PF07996.6 AAS54101.2 - 0.0077 16.1 0.4 0.011 15.6 0.3 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins ATP_transf PF09830.4 AAS54102.2 - 1e-17 63.6 0.0 7.9e-17 60.8 0.0 2.3 2 0 0 2 2 2 1 ATP adenylyltransferase HIT PF01230.18 AAS54102.2 - 4.6e-07 30.2 0.0 1.1e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 HIT domain UCR_14kD PF02271.11 AAS54103.1 - 5.4e-45 151.4 0.3 6.1e-45 151.2 0.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Senescence_reg PF04520.8 AAS54104.1 - 0.0093 16.4 1.9 1.3 9.5 0.2 2.1 2 0 0 2 2 2 2 Senescence regulator PIG-X PF08320.7 AAS54105.2 - 1.7e-51 174.4 0.0 2.7e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 Spb1_C PF07780.7 AAS54106.2 - 1.9e-77 259.6 30.7 1.9e-77 259.6 21.3 3.3 3 0 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 AAS54106.2 - 1e-57 194.1 17.2 1e-57 194.1 11.9 4.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 AAS54106.2 - 3.4e-53 180.3 0.8 9e-53 178.9 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF1796 PF08795.5 AAS54106.2 - 0.1 12.2 2.0 0.21 11.1 0.2 2.4 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) CMAS PF02353.15 AAS54107.1 - 3.5e-61 206.6 0.1 4.3e-61 206.3 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 AAS54107.1 - 5.9e-11 42.3 0.0 1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AAS54107.1 - 3e-07 30.8 0.0 6.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS54107.1 - 1.2e-05 25.8 0.0 2.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AAS54107.1 - 1.5e-05 24.9 0.0 5.7e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AAS54107.1 - 8.6e-05 22.9 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS54107.1 - 0.00019 21.0 0.0 0.0004 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AAS54107.1 - 0.0013 18.7 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 AAS54107.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 AAS54107.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 AAS54107.1 - 0.015 15.6 0.0 0.036 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 AAS54107.1 - 0.072 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MT-A70 PF05063.9 AAS54108.1 - 1.1e-13 51.1 0.0 1.6e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 MT-A70 DUF3414 PF11894.3 AAS54109.1 - 0.022 11.6 0.1 0.028 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) Voltage_CLC PF00654.15 AAS54110.2 - 6.9e-87 291.7 15.7 6.9e-87 291.7 10.9 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel 2OG-FeII_Oxy_2 PF13532.1 AAS54113.1 - 3.7e-20 72.5 0.0 4.8e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_ribbon_recom PF13408.1 AAS54113.1 - 0.0086 16.3 4.0 0.022 15.0 2.8 1.7 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Borrelia_lipo_1 PF05714.6 AAS54113.1 - 0.057 12.5 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein NCKAP5 PF15246.1 AAS54113.1 - 0.21 10.9 0.0 0.3 10.4 0.0 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein PEX11 PF05648.9 AAS54114.2 - 0.023 13.9 0.4 0.033 13.4 0.3 1.3 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF543 PF04418.7 AAS54115.1 - 5.1e-30 103.2 0.6 5.7e-30 103.0 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) NADH_dh_m_C1 PF15088.1 AAS54115.1 - 0.14 11.6 3.8 4 7.0 0.2 2.2 1 1 1 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial IncFII_repA PF02387.10 AAS54116.1 - 0.76 8.8 4.4 0.96 8.5 3.1 1.1 1 0 0 1 1 1 0 IncFII RepA protein family DUF4407 PF14362.1 AAS54116.1 - 1.6 7.6 11.1 1.7 7.5 7.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KH_1 PF00013.24 AAS54117.2 - 0.0092 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 AAS54117.2 - 0.052 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 KH domain CT47 PF15623.1 AAS54117.2 - 1.6 8.3 15.3 2.2 7.9 10.6 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 MRC1 PF09444.5 AAS54118.1 - 5.8e-49 166.1 8.7 5.8e-49 166.1 6.0 4.5 5 0 0 5 5 5 1 MRC1-like domain PALP PF00291.20 AAS54120.1 - 6.5e-59 199.6 0.0 7.8e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme BPD_transp_1 PF00528.17 AAS54121.1 - 0.039 13.4 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component Pox_A14 PF05767.7 AAS54122.1 - 0.22 11.5 6.0 0.34 10.8 2.1 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 PhaG_MnhG_YufB PF03334.9 AAS54123.1 - 0.0039 17.2 8.2 0.42 10.6 0.3 2.9 1 1 2 3 3 3 2 Na+/H+ antiporter subunit Fun_ATP-synt_8 PF05933.8 AAS54124.1 - 1.1e-12 47.7 10.8 1.2e-12 47.6 7.5 1.0 1 0 0 1 1 1 1 Fungal ATP synthase protein 8 (A6L) AA_synth PF06684.6 AAS54125.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Amino acid synthesis PTR2 PF00854.16 AAS54126.1 - 1.3e-32 113.0 3.1 3.5e-31 108.3 2.2 2.3 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 AAS54126.1 - 4.8e-09 35.3 20.1 5.4e-07 28.6 0.3 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily ATE_N PF04376.8 AAS54126.1 - 0.2 11.4 0.3 0.38 10.5 0.2 1.4 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, N terminus FH2 PF02181.18 AAS54127.1 - 1.7e-68 231.2 9.2 1.7e-68 231.2 6.4 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 AAS54127.1 - 0.00021 20.6 1.1 0.00021 20.6 0.8 3.1 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain BEX PF04538.7 AAS54127.1 - 0.0084 16.3 0.1 0.0084 16.3 0.1 2.8 3 0 0 3 3 3 1 Brain expressed X-linked like family Transp_cyt_pur PF02133.10 AAS54128.1 - 3e-69 233.6 32.1 4e-69 233.2 22.2 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3545 PF12065.3 AAS54129.1 - 0.46 10.2 2.0 0.9 9.3 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) Zn_clus PF00172.13 AAS54130.1 - 7.8e-08 32.0 8.6 1.5e-07 31.1 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 AAS54131.1 - 1.2e-17 63.6 0.3 1.8e-17 63.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AAS54131.1 - 0.013 16.4 0.0 0.025 15.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 AAS54131.1 - 0.051 13.1 0.3 0.094 12.2 0.2 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RNA12 PF10443.4 AAS54133.1 - 3.5e-171 569.4 0.0 5e-171 568.9 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.17 AAS54133.1 - 3.2e-07 29.8 0.0 9.2e-07 28.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 AAS54133.1 - 7.6e-07 29.0 0.0 5.3e-06 26.2 0.0 2.3 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 AAS54133.1 - 0.00045 20.1 0.0 0.0033 17.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AAS54133.1 - 0.0016 18.5 0.0 0.039 14.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain RRM_5 PF13893.1 AAS54133.1 - 0.0026 17.5 0.0 0.0076 16.0 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CpeT PF06206.6 AAS54133.1 - 0.044 13.4 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) AAA_19 PF13245.1 AAS54133.1 - 0.1 12.3 0.1 4.3 7.1 0.0 2.8 3 0 0 3 3 3 0 Part of AAA domain USP7_C2 PF14533.1 AAS54134.1 - 5.7e-59 199.1 7.2 7.3e-57 192.2 1.8 3.6 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 AAS54134.1 - 3.3e-53 180.5 1.9 6.3e-53 179.6 1.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 AAS54134.1 - 1.3e-33 116.2 0.7 8.8e-33 113.5 0.1 2.4 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 AAS54134.1 - 9.2e-33 113.9 0.0 2e-32 112.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UN_NPL4 PF11543.3 AAS54134.1 - 0.21 11.8 2.8 0.68 10.2 0.0 3.3 4 0 0 4 4 4 0 Nuclear pore localisation protein NPL4 CTP_transf_2 PF01467.21 AAS54135.1 - 4.4e-12 46.3 0.0 6.1e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase MA3 PF02847.12 AAS54136.1 - 1.2e-20 73.3 0.0 3.2e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.14 AAS54136.1 - 0.0044 16.4 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 MIF4G domain Glyco_hydro_17 PF00332.13 AAS54137.1 - 1.7e-07 30.6 0.4 8e-07 28.3 0.1 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 TFIIA PF03153.8 AAS54137.1 - 3.4 7.4 4.7 4.9 6.9 3.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.5 AAS54137.1 - 5 6.2 7.9 7.1 5.7 5.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Glucan_synthase PF02364.10 AAS54138.1 - 0 1348.1 0.1 0 1348.1 0.0 1.7 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 AAS54138.1 - 7.4e-39 132.2 0.8 1.7e-38 131.1 0.0 2.1 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.9 AAS54139.2 - 1e-136 455.0 6.8 1.4e-136 454.6 4.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 AAS54139.2 - 1.4e-25 89.5 6.9 4e-25 88.1 4.8 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 AAS54139.2 - 0.00048 19.4 0.2 0.0034 16.6 0.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_72 PF03198.9 AAS54140.2 - 1.6e-140 467.5 6.5 2.2e-140 467.1 4.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 AAS54140.2 - 8.8e-28 96.6 3.7 2.8e-27 95.0 2.6 1.9 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 AAS54140.2 - 0.0028 16.9 0.2 0.055 12.6 0.1 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_L7Ae PF01248.21 AAS54140.2 - 0.012 15.0 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family G-patch PF01585.18 AAS54141.1 - 8.6e-11 41.4 0.1 2e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 AAS54141.1 - 0.00012 21.8 0.3 0.00012 21.8 0.2 4.0 2 1 0 2 2 2 1 DExH-box splicing factor binding site MIP-T3 PF10243.4 AAS54141.1 - 0.015 13.7 54.4 0.021 13.3 37.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mem_trans PF03547.13 AAS54141.1 - 0.044 12.0 8.7 0.067 11.4 6.1 1.2 1 0 0 1 1 1 0 Membrane transport protein CDC27 PF09507.5 AAS54141.1 - 0.088 12.0 43.5 0.12 11.5 30.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4407 PF14362.1 AAS54141.1 - 4.5 6.1 19.1 5.6 5.8 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Parvo_coat PF00740.13 AAS54141.1 - 6.9 5.5 11.9 8.9 5.1 8.3 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 PLRV_ORF5 PF01690.12 AAS54141.1 - 9.3 5.2 27.1 14 4.7 18.8 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein HEAT_EZ PF13513.1 AAS54142.2 - 2.4e-17 62.8 6.8 1.9e-06 28.1 0.0 9.4 9 1 2 11 11 11 3 HEAT-like repeat HEAT_2 PF13646.1 AAS54142.2 - 6.5e-17 61.6 0.0 6.1e-08 32.8 0.0 5.6 4 2 1 5 5 5 3 HEAT repeats HEAT PF02985.17 AAS54142.2 - 6.9e-17 59.9 5.2 0.015 15.3 0.0 9.2 10 0 0 10 10 10 4 HEAT repeat MMS19_C PF12460.3 AAS54142.2 - 6.8e-07 28.3 5.6 0.0056 15.4 0.9 4.5 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal RIX1 PF08167.7 AAS54142.2 - 3.5e-06 26.7 0.4 0.005 16.5 0.1 4.4 4 1 0 5 5 5 1 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.2 AAS54142.2 - 4.6e-06 26.9 0.0 0.079 13.3 0.0 5.7 3 1 3 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 AAS54142.2 - 4.5e-05 22.9 0.9 0.069 12.4 0.4 4.5 3 2 1 4 4 4 1 CLASP N terminal Arm PF00514.18 AAS54142.2 - 5.2e-05 22.9 2.8 2.6 8.0 0.0 4.6 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat DUF3385 PF11865.3 AAS54142.2 - 0.019 14.9 0.1 0.9 9.4 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Fungal_trans PF04082.13 AAS54143.1 - 8.8e-18 64.1 1.5 1.9e-17 63.0 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain CBS PF00571.23 AAS54144.1 - 5.6e-22 77.2 0.0 7.6e-07 28.8 0.0 4.5 4 1 0 4 4 4 4 CBS domain ABC_membrane PF00664.18 AAS54145.2 - 9.1e-61 205.6 34.3 3.8e-34 118.3 10.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AAS54145.2 - 2.9e-45 153.9 0.1 4.8e-27 94.9 0.0 3.6 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.14 AAS54145.2 - 3.6e-11 42.7 0.0 0.00043 19.5 0.0 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AAS54145.2 - 3.2e-07 30.5 0.8 0.0022 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 AAS54145.2 - 2e-06 27.9 0.3 0.43 10.4 0.0 4.2 2 2 2 4 4 4 2 AAA domain AAA_17 PF13207.1 AAS54145.2 - 3.3e-06 27.9 1.2 0.088 13.6 0.0 3.6 3 0 0 3 3 3 2 AAA domain ATP-synt_ab PF00006.20 AAS54145.2 - 7.7e-05 22.2 0.2 0.012 15.1 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 AAS54145.2 - 0.00027 20.1 1.5 0.014 14.5 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 AAS54145.2 - 0.00041 20.8 1.5 0.36 11.3 0.1 2.8 2 0 0 2 2 2 1 Miro-like protein Zeta_toxin PF06414.7 AAS54145.2 - 0.00042 19.4 0.4 0.5 9.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA PF00004.24 AAS54145.2 - 0.0012 19.0 0.3 0.089 13.0 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 AAS54145.2 - 0.0045 16.5 1.9 0.38 10.3 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 AAS54145.2 - 0.009 14.9 2.2 0.11 11.4 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein PduV-EutP PF10662.4 AAS54145.2 - 0.01 15.3 0.5 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 AAS54145.2 - 0.029 13.9 4.2 0.17 11.4 0.2 3.3 4 0 0 4 4 3 0 AAA domain AAA_23 PF13476.1 AAS54145.2 - 0.03 14.6 4.6 5.2 7.3 1.1 2.9 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 AAS54145.2 - 0.032 13.6 1.4 3.7 6.9 0.0 3.0 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 AAS54145.2 - 0.039 13.3 2.0 1.7 8.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 AAS54145.2 - 0.043 13.5 1.1 0.47 10.2 0.1 3.0 2 0 0 2 2 2 0 Part of AAA domain MMR_HSR1 PF01926.18 AAS54145.2 - 0.055 13.4 2.5 5.5 6.9 0.4 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 AAS54145.2 - 0.056 13.3 2.0 6.4 6.6 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 AAS54145.2 - 0.082 13.0 8.5 1.3 9.1 0.2 3.8 3 1 0 3 3 3 0 AAA domain UPF0079 PF02367.12 AAS54145.2 - 0.1 12.2 1.4 1.9 8.1 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_26 PF13500.1 AAS54145.2 - 0.19 11.2 1.5 13 5.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 AAS54145.2 - 0.21 11.2 2.8 2.2 7.9 0.3 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 AAS54145.2 - 1.2 9.1 7.0 0.3 11.0 0.2 2.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 AAS54145.2 - 1.9 8.7 12.4 1.4 9.1 0.3 3.4 5 0 0 5 5 2 0 AAA domain Dynamin_N PF00350.18 AAS54145.2 - 2.3 8.0 7.2 0.62 9.8 0.3 2.7 3 0 0 3 3 2 0 Dynamin family FtsK_SpoIIIE PF01580.13 AAS54145.2 - 3.6 7.0 6.8 6.7 6.1 0.0 3.1 4 0 0 4 4 4 0 FtsK/SpoIIIE family HMG_box PF00505.14 AAS54146.2 - 0.0035 17.5 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box eIF-3c_N PF05470.7 AAS54147.1 - 1.2e-154 515.6 18.2 5.4e-120 401.2 2.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 AAS54147.1 - 3.4e-11 43.3 5.5 8.6e-11 42.0 0.4 3.9 4 1 0 4 4 4 1 PCI domain Ret_tiss PF10044.4 AAS54147.1 - 0.047 14.2 0.2 0.3 11.6 0.1 2.4 1 0 0 1 1 1 0 Retinal tissue protein Glyco_hydro_17 PF00332.13 AAS54148.2 - 7.5e-61 205.8 0.0 8.8e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Methyltrn_RNA_3 PF02598.12 AAS54149.1 - 2.6e-99 332.2 0.0 3.1e-99 332.0 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase IPP-2 PF04979.9 AAS54150.1 - 2.8e-06 27.6 5.2 2.8e-06 27.6 3.6 2.0 1 1 1 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Sigma70_ner PF04546.8 AAS54150.1 - 0.061 12.9 4.9 0.1 12.2 3.4 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region I_LWEQ PF01608.12 AAS54150.1 - 0.65 9.9 2.7 4.7 7.1 0.1 2.1 2 0 0 2 2 2 0 I/LWEQ domain SURF4 PF02077.10 AAS54151.1 - 1.1e-94 316.7 11.9 1.3e-94 316.5 8.3 1.0 1 0 0 1 1 1 1 SURF4 family DUF950 PF06106.6 AAS54151.1 - 0.1 12.7 0.5 0.53 10.3 0.0 2.1 2 1 0 2 2 2 0 Staphylococcus protein of unknown function (DUF950) DnaJ PF00226.26 AAS54152.1 - 1.8e-17 62.8 0.7 1.8e-17 62.8 0.5 2.4 2 0 0 2 2 2 1 DnaJ domain DUF3336 PF11815.3 AAS54154.1 - 1.5e-27 95.8 0.0 2.9e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 AAS54154.1 - 2e-09 37.7 0.0 4.5e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Proteasome PF00227.21 AAS54155.1 - 6.8e-47 159.2 0.1 9.7e-47 158.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AAS54155.1 - 1.3e-12 46.7 0.2 2.6e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ABC_tran PF00005.22 AAS54156.1 - 1.9e-34 118.8 0.0 3.4e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 AAS54156.1 - 2.8e-33 115.5 15.6 3.5e-33 115.2 10.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 AAS54156.1 - 7.2e-10 39.2 0.9 2.2e-05 24.5 0.1 3.3 2 2 0 2 2 2 1 AAA domain SMC_N PF02463.14 AAS54156.1 - 7.6e-09 35.1 0.2 4.4e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AAS54156.1 - 5.6e-06 26.4 0.0 1.6e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 AAS54156.1 - 0.00015 21.1 0.1 0.00038 19.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.4 AAS54156.1 - 0.00046 18.8 0.1 0.042 12.4 0.1 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_17 PF13207.1 AAS54156.1 - 0.0041 17.9 0.0 0.0084 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AAS54156.1 - 0.0066 16.5 0.1 0.027 14.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AAS54156.1 - 0.0095 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 AAS54156.1 - 0.0098 16.2 0.3 0.027 14.8 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AAS54156.1 - 0.02 14.2 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 AAS54156.1 - 0.033 13.3 0.0 0.069 12.2 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF258 PF03193.11 AAS54156.1 - 0.055 12.6 0.0 0.15 11.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 AAS54156.1 - 0.063 12.8 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 AAS54156.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 AAS54156.1 - 0.091 13.0 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 AAS54156.1 - 0.2 11.5 1.4 1.1 9.2 0.3 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit GATase_2 PF00310.16 AAS54157.1 - 9.1e-24 83.8 0.0 4.5e-18 65.1 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 AAS54157.1 - 5.5e-16 58.7 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 AAS54157.1 - 3.1e-13 49.5 0.0 5.9e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 AAS54157.1 - 4.6e-12 45.7 0.1 1.5e-11 44.0 0.1 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 AAS54157.1 - 0.00015 20.5 0.0 0.00024 19.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DLIC PF05783.6 AAS54158.1 - 0.00016 20.4 0.0 0.00032 19.5 0.0 1.4 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) TRAPP PF04051.11 AAS54158.1 - 0.14 11.6 0.1 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component RNase_T PF00929.19 AAS54159.2 - 2.5e-26 92.8 0.1 4.7e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Exonuclease FMN_bind PF04205.9 AAS54159.2 - 0.076 13.1 0.1 0.63 10.2 0.0 2.5 2 0 0 2 2 2 0 FMN-binding domain Rtt102p PF09510.5 AAS54160.1 - 1e-42 145.1 0.0 1.6e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Rtt102p-like transcription regulator protein DUF3591 PF12157.3 AAS54161.1 - 1.8e-202 672.7 1.0 3.5e-202 671.8 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 AAS54161.1 - 8.9e-08 31.6 0.8 2e-07 30.5 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Peptidase_S10 PF00450.17 AAS54163.1 - 1e-129 433.3 0.1 1.3e-129 433.0 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 AAS54163.1 - 9.7e-10 38.6 0.0 1.7e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Peptidase_M20 PF01546.23 AAS54165.1 - 2.4e-06 27.2 0.0 3.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3322 PF11795.3 AAS54165.1 - 0.0027 17.3 0.1 0.0074 15.9 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) Peptidase_M20 PF01546.23 AAS54166.2 - 3.3e-25 88.6 0.0 4.6e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AAS54166.2 - 7.5e-11 41.7 0.0 2.3e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain WT1 PF02165.10 AAS54166.2 - 0.09 11.8 0.1 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 Wilm's tumour protein Peptidase_M28 PF04389.12 AAS54166.2 - 0.093 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Proteasome PF00227.21 AAS54167.2 - 6.7e-39 133.1 0.1 4.3e-38 130.5 0.1 1.9 1 1 0 1 1 1 1 Proteasome subunit ER_lumen_recept PF00810.13 AAS54168.1 - 2.5e-50 170.7 12.5 3.6e-50 170.2 8.7 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor Sod_Cu PF00080.15 AAS54170.2 - 2.5e-46 157.3 2.8 2.9e-46 157.1 1.9 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CTP_synth_N PF06418.9 AAS54171.1 - 2.1e-118 394.3 0.1 2.9e-118 393.9 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 AAS54171.1 - 3.4e-57 193.0 0.0 5.1e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AAS54171.1 - 0.00018 20.9 0.0 0.00061 19.3 0.0 1.9 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 AAS54171.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Antimicrobial_1 PF08018.6 AAS54171.1 - 0.27 11.1 1.2 0.61 10.0 0.8 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide TilS PF09179.6 AAS54172.1 - 0.00082 19.3 1.1 0.00082 19.3 0.7 3.1 2 1 1 3 3 3 2 TilS substrate binding domain ATP-synt_DE PF00401.15 AAS54172.1 - 0.0076 16.1 0.9 0.0076 16.1 0.7 2.4 3 0 0 3 3 3 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain ESCRT-II PF05871.7 AAS54173.1 - 6e-41 139.6 0.0 7.7e-41 139.2 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Sod_Fe_C PF02777.13 AAS54174.1 - 5.5e-14 51.8 0.2 3e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Peptidase_C12 PF01088.16 AAS54175.2 - 4.5e-58 195.9 0.0 6.2e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SAC3_GANP PF03399.11 AAS54176.2 - 2.3e-51 174.2 4.9 3.5e-51 173.6 3.4 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 AAS54176.2 - 1.8e-05 24.5 1.6 4.1e-05 23.3 1.1 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DTHCT PF08070.6 AAS54176.2 - 0.0027 18.3 3.2 0.0027 18.3 2.2 1.7 2 0 0 2 2 2 1 DTHCT (NUC029) region Peptidase_C12 PF01088.16 AAS54177.1 - 1.5e-46 158.2 0.0 1.8e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PX PF00787.19 AAS54178.2 - 4.2e-08 32.9 0.0 7.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.22 AAS54180.2 - 1.8e-71 235.8 0.8 4.1e-23 80.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UBA_2 PF08587.6 AAS54180.2 - 0.09 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Ribosomal_L37ae PF01780.14 AAS54181.1 - 7.3e-40 134.7 9.1 8.2e-40 134.5 6.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Rep_fac-A_C PF08646.5 AAS54181.1 - 0.0038 16.9 0.4 0.0043 16.7 0.2 1.2 1 0 0 1 1 1 1 Replication factor-A C terminal domain Zn_Tnp_IS1595 PF12760.2 AAS54181.1 - 0.015 15.0 2.5 0.024 14.4 1.7 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF1364 PF07102.7 AAS54181.1 - 0.019 14.8 1.0 0.025 14.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) DUF2175 PF09943.4 AAS54181.1 - 0.02 14.9 0.3 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Sgf11 PF08209.6 AAS54181.1 - 0.029 13.6 0.7 0.53 9.6 0.0 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-H2C2_2 PF13465.1 AAS54181.1 - 0.052 13.8 0.8 1.8 8.9 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain C1_1 PF00130.17 AAS54181.1 - 0.08 12.6 1.9 0.12 12.1 1.3 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CarbpepA_inh PF02977.10 AAS54181.1 - 0.092 12.3 3.9 0.11 12.0 0.5 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor zf-C4_ClpX PF06689.8 AAS54181.1 - 0.13 11.7 0.3 0.13 11.7 0.2 2.1 2 0 0 2 2 2 0 ClpX C4-type zinc finger OrfB_Zn_ribbon PF07282.6 AAS54181.1 - 0.16 11.6 2.6 0.22 11.1 1.8 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.5 AAS54181.1 - 0.38 10.2 2.5 12 5.5 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Elf1 PF05129.8 AAS54181.1 - 0.39 10.4 3.2 0.95 9.2 2.2 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like YyzF PF14116.1 AAS54181.1 - 0.44 10.5 0.2 0.44 10.5 0.1 1.6 2 0 0 2 2 2 0 YyzF-like protein Beta-TrCP_D PF12125.3 AAS54183.1 - 0.055 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 D domain of beta-TrCP Fip1 PF05182.8 AAS54184.1 - 1.2e-23 82.0 0.5 1.9e-23 81.4 0.4 1.3 1 0 0 1 1 1 1 Fip1 motif Nop14 PF04147.7 AAS54184.1 - 0.49 8.2 15.8 0.64 7.8 10.9 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 AAS54184.1 - 0.9 7.9 9.0 1.1 7.7 6.3 1.2 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 AAS54184.1 - 1 7.6 13.9 4.5 5.5 10.2 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.7 AAS54184.1 - 1.6 7.9 13.4 2.3 7.4 9.3 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.8 AAS54184.1 - 5.2 4.7 10.1 7.1 4.2 7.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Anillin PF08174.6 AAS54185.1 - 1.4e-12 47.8 0.1 1.4e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.24 AAS54185.1 - 2.2e-06 27.7 0.9 5.3e-06 26.5 0.1 2.1 2 0 0 2 2 2 1 PH domain PUF PF00806.14 AAS54186.2 - 1.4e-29 99.9 1.0 0.00026 20.2 0.0 6.8 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat RRM_1 PF00076.17 AAS54186.2 - 6.5e-06 25.6 0.0 1.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS54186.2 - 2e-05 24.3 0.0 4.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 AAS54186.2 - 0.018 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Calcipressin RRM_6 PF14259.1 AAS54186.2 - 0.17 11.8 0.0 0.51 10.3 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MAM1 PF10434.4 AAS54187.1 - 2.1e-107 358.3 0.8 2.6e-107 358.0 0.6 1.0 1 0 0 1 1 1 1 Monopolin complex protein MAM1 Pfg27 PF09216.5 AAS54187.1 - 0.11 12.1 0.2 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Pfg27 GatB_N PF02934.10 AAS54188.1 - 1.2e-93 313.1 0.0 1.6e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 AAS54188.1 - 1.5e-33 115.6 0.0 2.5e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 GatB domain WD40 PF00400.27 AAS54190.1 - 8.8e-30 101.4 5.5 1e-06 28.4 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 AAS54190.1 - 6e-05 21.3 0.4 0.018 13.1 0.2 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 LisH PF08513.6 AAS54191.2 - 1.6e-08 33.9 0.6 2.8e-08 33.2 0.4 1.4 1 0 0 1 1 1 1 LisH ALG3 PF05208.8 AAS54192.2 - 5.6e-122 407.5 20.7 7e-122 407.2 14.4 1.1 1 0 0 1 1 1 1 ALG3 protein HEAT_EZ PF13513.1 AAS54193.2 - 2.6e-18 65.9 2.4 0.014 15.9 0.0 8.9 6 3 2 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.1 AAS54193.2 - 3.4e-14 52.8 13.4 0.00014 22.0 0.1 7.2 7 1 0 7 7 7 3 HEAT repeats HEAT PF02985.17 AAS54193.2 - 7.8e-13 47.3 7.4 0.046 13.8 0.0 9.4 10 0 0 10 10 10 3 HEAT repeat IBN_N PF03810.14 AAS54193.2 - 2.9e-08 33.5 6.3 4.6e-06 26.4 0.0 5.0 4 1 1 5 5 5 1 Importin-beta N-terminal domain Ipi1_N PF12333.3 AAS54193.2 - 1.2e-07 31.6 0.4 0.29 11.1 0.0 5.3 4 1 1 5 5 5 3 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.2 AAS54193.2 - 4.1e-07 30.2 6.0 2.1 8.8 0.0 6.6 5 1 1 6 6 6 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 AAS54193.2 - 1.6e-05 24.3 9.8 1.3 8.3 0.1 6.4 7 0 0 7 7 7 2 CLASP N terminal Sec7_N PF12783.2 AAS54193.2 - 0.0015 18.0 1.5 0.026 13.9 0.1 3.4 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal PAD_M PF08527.5 AAS54193.2 - 0.032 13.6 0.1 0.25 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain Ank_4 PF13637.1 AAS54194.1 - 4e-09 36.7 4.2 0.00011 22.5 0.1 3.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 AAS54194.1 - 3.9e-08 33.5 1.7 0.0059 16.9 0.1 3.4 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) KilA-N PF04383.8 AAS54194.1 - 6.3e-07 28.9 0.2 4.6e-06 26.2 0.1 2.5 1 1 0 1 1 1 1 KilA-N domain Ank_5 PF13857.1 AAS54194.1 - 1.4e-06 28.3 0.8 0.0062 16.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 AAS54194.1 - 1.8e-06 27.4 2.5 0.011 15.4 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 AAS54194.1 - 0.00012 21.9 2.3 0.21 11.9 0.1 4.0 3 0 0 3 3 3 1 Ankyrin repeat LSM PF01423.17 AAS54195.1 - 5e-14 51.5 0.1 1.1e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AAS54195.1 - 0.007 16.2 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.6 AAS54195.1 - 0.7 10.3 19.3 1.2 9.6 13.4 1.4 1 0 0 1 1 1 0 Glycine rich protein family EMP70 PF02990.11 AAS54196.1 - 1.7e-48 165.3 0.5 1.9e-47 161.9 0.4 2.0 1 1 0 1 1 1 1 Endomembrane protein 70 TPR_2 PF07719.12 AAS54197.1 - 2.4e-43 142.5 7.2 1.7e-07 30.5 0.0 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 AAS54197.1 - 1.8e-42 142.8 21.8 5.4e-14 51.5 2.9 7.5 3 2 5 8 8 8 5 TPR repeat TPR_1 PF00515.23 AAS54197.1 - 1.3e-36 122.7 15.9 3.4e-08 32.7 0.0 8.7 11 0 0 11 11 9 6 Tetratricopeptide repeat Apc3 PF12895.2 AAS54197.1 - 1.7e-36 124.2 26.6 6.7e-22 77.4 2.8 5.4 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AAS54197.1 - 3e-32 107.9 3.3 5.5e-05 22.6 0.3 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 AAS54197.1 - 9.9e-24 83.4 3.4 2.3e-07 31.2 0.0 5.8 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 AAS54197.1 - 9.3e-23 78.4 15.9 3e-05 23.8 0.2 8.7 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 AAS54197.1 - 6.4e-22 77.2 18.8 1.6e-06 27.9 1.0 8.2 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 AAS54197.1 - 5e-19 67.0 4.6 0.031 14.9 0.0 8.4 5 3 4 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 AAS54197.1 - 8.9e-16 57.9 5.2 4.9e-05 23.5 0.0 5.4 6 0 0 6 6 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 AAS54197.1 - 1.2e-14 52.8 1.7 0.25 11.2 0.0 7.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 AAS54197.1 - 3.7e-13 48.9 19.5 0.041 14.3 0.0 10.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_15 PF13429.1 AAS54197.1 - 1e-10 41.1 4.0 0.0051 15.9 0.0 5.1 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 AAS54197.1 - 0.00014 21.6 0.1 0.25 11.2 0.0 3.7 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 AAS54197.1 - 0.0002 21.1 6.1 1.3 9.0 0.0 6.0 8 0 0 8 8 6 1 Tetratricopeptide repeat DUF3856 PF12968.2 AAS54197.1 - 0.00072 19.4 0.6 1.3 8.8 0.2 4.9 3 1 1 4 4 4 1 Domain of Unknown Function (DUF3856) BTAD PF03704.12 AAS54197.1 - 0.0055 17.0 0.0 0.28 11.4 0.0 2.9 2 1 1 3 3 2 1 Bacterial transcriptional activator domain TPR_4 PF07721.9 AAS54197.1 - 0.01 16.1 3.0 3.8 8.2 0.0 4.6 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 AAS54197.1 - 0.075 13.1 0.1 38 4.5 0.0 3.6 4 1 1 5 5 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 AAS54197.1 - 0.13 12.1 17.3 0.66 9.8 0.5 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AAS54197.1 - 0.19 11.6 13.1 7.3 6.5 0.5 5.9 5 2 2 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 AAS54197.1 - 3.4 7.6 5.3 22 5.0 0.0 4.5 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain PPR PF01535.15 AAS54197.1 - 7.3 6.8 7.8 31 4.8 0.0 4.1 5 0 0 5 5 3 0 PPR repeat SH3_1 PF00018.23 AAS54198.1 - 1.1e-13 50.3 0.2 2.2e-13 49.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 AAS54198.1 - 3.6e-13 49.6 0.0 9.2e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 AAS54198.1 - 7.4e-12 44.9 0.0 1.3e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 AAS54198.1 - 6.2e-09 35.3 0.1 1.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 AAS54198.1 - 7.2e-09 35.8 0.0 4.4e-08 33.3 0.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.25 AAS54198.1 - 3.9e-05 23.7 0.0 6.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 AAS54198.1 - 5.6e-05 22.5 0.0 0.00018 20.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain PH_8 PF15409.1 AAS54198.1 - 0.00034 20.6 0.0 0.011 15.7 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain NEP PF10167.4 AAS54198.1 - 0.027 14.1 0.1 0.084 12.5 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised conserved protein SAM_PNT PF02198.11 AAS54198.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain NT-C2 PF10358.4 AAS54200.1 - 5.3e-40 136.1 0.0 9.3e-40 135.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF330 PF03886.8 AAS54200.1 - 0.072 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF330) zf-C3HC4 PF00097.20 AAS54202.1 - 3.6e-10 39.3 5.5 5.6e-10 38.7 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AAS54202.1 - 7.1e-10 38.4 5.4 1e-09 37.8 3.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AAS54202.1 - 2.1e-08 33.8 6.6 3.2e-08 33.2 4.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AAS54202.1 - 2.2e-07 30.4 6.3 3.5e-07 29.8 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AAS54202.1 - 4e-07 29.9 7.0 6.1e-07 29.3 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AAS54202.1 - 6.3e-05 22.6 3.8 0.00011 21.8 2.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AAS54202.1 - 0.0011 18.8 7.8 0.0018 18.1 5.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 AAS54202.1 - 0.0014 18.6 1.5 0.0022 18.0 1.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AAS54202.1 - 0.0027 17.5 2.0 0.0045 16.7 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 AAS54202.1 - 0.76 9.3 5.5 1.2 8.7 3.5 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 AAS54202.1 - 2.2 7.9 9.4 5.8 6.5 5.5 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_L14 PF00238.14 AAS54203.1 - 1e-31 109.2 0.0 1.1e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PI3_PI4_kinase PF00454.22 AAS54204.1 - 4.9e-47 160.3 0.0 1.2e-46 159.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 AAS54204.1 - 4.5e-18 65.4 0.0 1.6e-17 63.6 0.0 2.1 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 AAS54204.1 - 1.2e-10 40.6 0.0 3.4e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 FATC domain SH3_1 PF00018.23 AAS54205.1 - 7.3e-11 41.2 0.1 1.3e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AAS54205.1 - 2.7e-10 39.6 0.0 4.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AAS54205.1 - 5.2e-09 35.4 0.0 1.2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF4181 PF13789.1 AAS54205.1 - 0.017 15.0 2.6 0.029 14.3 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) Aa_trans PF01490.13 AAS54206.2 - 4.6e-95 318.5 9.1 5.4e-95 318.2 6.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 AAS54206.2 - 2.8e-05 23.1 10.7 6e-05 22.0 7.4 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Ribosomal_S21 PF01165.15 AAS54207.2 - 7.8e-11 41.2 4.7 7.8e-11 41.2 3.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S21 CaMBD PF02888.11 AAS54207.2 - 2 8.3 4.8 1.6 8.6 1.9 1.9 1 1 1 2 2 2 0 Calmodulin binding domain Peptidase_M24 PF00557.19 AAS54208.2 - 7.3e-49 166.1 0.1 9.2e-49 165.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Motile_Sperm PF00635.21 AAS54209.1 - 5.2e-25 87.2 0.5 8.3e-25 86.5 0.0 1.6 2 0 0 2 2 2 1 MSP (Major sperm protein) domain Ribosomal_L32e PF01655.13 AAS54210.1 - 5.1e-47 158.4 2.5 5.9e-47 158.2 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 DUF3437 PF11919.3 AAS54210.1 - 0.13 11.9 0.3 0.25 11.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Rox3 PF08633.5 AAS54211.1 - 1.4e-64 217.9 0.1 1.6e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Rox3 mediator complex subunit ArfGap PF01412.13 AAS54212.1 - 1.3e-34 118.4 1.5 1.6e-34 118.1 0.2 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf 4HBT PF03061.17 AAS54213.1 - 2.8e-07 30.5 0.1 5.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Sugar_tr PF00083.19 AAS54214.1 - 2.1e-78 263.9 31.0 2.7e-78 263.5 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AAS54214.1 - 3e-13 49.2 54.6 1.3e-11 43.8 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 AAS54215.1 - 1e-17 64.2 0.0 4.1e-17 62.2 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 AAS54215.1 - 2.5e-06 27.4 0.0 6.7e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AAS54215.1 - 1.1e-05 25.6 0.0 3e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AAS54215.1 - 2.5e-05 23.3 0.2 8.2e-05 21.6 0.0 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 AAS54215.1 - 4.1e-05 22.6 0.0 5.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 AAS54215.1 - 5e-05 23.0 0.0 8.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 AAS54215.1 - 0.0014 17.4 0.1 0.017 13.9 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase FAD_binding_2 PF00890.19 AAS54215.1 - 0.0037 16.1 0.0 0.0076 15.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 AAS54215.1 - 0.004 16.5 0.1 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 AAS54215.1 - 0.0047 16.8 0.2 0.0092 15.8 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 AAS54215.1 - 0.006 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 AAS54215.1 - 0.0063 16.2 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 AAS54215.1 - 0.014 13.8 0.0 0.022 13.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_2 PF03446.10 AAS54215.1 - 0.037 13.8 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_oxidored PF12831.2 AAS54215.1 - 0.039 13.0 0.9 0.069 12.2 0.6 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Cnd2 PF05786.9 AAS54216.1 - 6.1e-129 431.6 20.2 1.6e-128 430.3 14.0 1.7 1 1 0 1 1 1 1 Condensin complex subunit 2 DUF2939 PF11159.3 AAS54216.1 - 0.082 13.0 0.9 10 6.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) Peptidase_M41 PF01434.13 AAS54217.1 - 9e-72 240.9 0.3 1.6e-71 240.2 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AAS54217.1 - 3.5e-41 140.5 0.0 1.3e-40 138.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AAS54217.1 - 1.1e-05 25.5 0.2 7.6e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AAS54217.1 - 3.1e-05 24.1 0.1 0.026 14.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AAS54217.1 - 0.00034 21.4 0.0 0.0012 19.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 AAS54217.1 - 0.00045 19.0 0.0 0.0009 18.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 AAS54217.1 - 0.00098 18.8 1.3 0.0035 17.0 0.9 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 AAS54217.1 - 0.0013 18.1 1.0 0.058 12.7 0.2 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 AAS54217.1 - 0.0017 18.0 0.1 0.0064 16.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 AAS54217.1 - 0.0018 17.3 0.0 0.0037 16.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 AAS54217.1 - 0.0045 16.4 0.0 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 AAS54217.1 - 0.022 14.6 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AAS54217.1 - 0.023 13.7 0.0 0.048 12.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 AAS54217.1 - 0.026 13.6 0.4 0.5 9.4 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA_33 PF13671.1 AAS54217.1 - 0.029 14.2 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 AAS54217.1 - 0.029 14.6 0.4 0.065 13.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 AAS54217.1 - 0.042 13.0 0.1 0.091 11.9 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 AAS54217.1 - 0.076 12.9 0.0 0.29 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 AAS54217.1 - 0.096 12.6 0.1 0.3 11.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain Peptidase_M50B PF13398.1 AAS54217.1 - 0.17 11.2 0.6 0.74 9.1 0.0 2.0 2 0 0 2 2 2 0 Peptidase M50B-like Cyclin_N PF00134.18 AAS54218.1 - 3.2e-08 33.1 0.4 6.3e-08 32.2 0.3 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain UvsY PF11056.3 AAS54218.1 - 0.0024 17.9 0.1 0.0063 16.6 0.0 1.6 1 0 0 1 1 1 1 Recombination, repair and ssDNA binding protein UvsY TFIIB PF00382.14 AAS54218.1 - 0.0066 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat DUF2320 PF10082.4 AAS54218.1 - 0.054 12.2 0.0 0.088 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2320) ATP-synt_ab PF00006.20 AAS54219.1 - 7e-71 238.1 0.0 1.1e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AAS54219.1 - 1.3e-26 93.2 0.6 3.8e-26 91.7 0.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AAS54219.1 - 2.1e-17 63.0 2.4 5.5e-17 61.7 1.7 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 AAS54219.1 - 0.0015 18.4 1.5 0.0035 17.2 1.1 1.7 1 0 0 1 1 1 1 HAS barrel domain AAA_25 PF13481.1 AAS54219.1 - 0.02 14.3 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tex_N PF09371.5 AAS54219.1 - 0.035 13.4 0.0 0.085 12.1 0.0 1.6 1 0 0 1 1 1 0 Tex-like protein N-terminal domain Glyco_hydro_65m PF03632.10 AAS54220.1 - 1.3e-94 316.9 1.5 7.1e-94 314.5 1.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 AAS54220.1 - 5e-31 107.9 0.0 9.9e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 AAS54220.1 - 6.1e-09 35.8 0.0 2.2e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain INCENP_ARK-bind PF03941.10 AAS54222.1 - 6.5e-22 77.1 0.1 1.4e-21 76.1 0.1 1.6 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region TPR_11 PF13414.1 AAS54223.1 - 1.4e-20 72.6 7.1 5.7e-12 45.0 0.6 2.6 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 AAS54223.1 - 1.4e-13 49.7 5.3 6.5e-06 25.5 1.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 AAS54223.1 - 4.7e-11 41.7 3.6 0.0002 21.0 0.6 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 AAS54223.1 - 7.9e-09 35.9 0.7 1.1e-06 29.1 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 AAS54223.1 - 9.1e-06 25.7 0.5 2e-05 24.6 0.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 AAS54223.1 - 6.5e-05 22.4 0.8 0.063 13.0 0.1 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 AAS54223.1 - 0.00011 22.0 0.5 0.0007 19.6 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 AAS54223.1 - 0.00073 19.9 0.2 0.34 11.6 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AAS54223.1 - 0.00085 19.2 1.4 0.17 11.8 0.1 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 AAS54223.1 - 0.0033 17.7 0.2 0.011 16.0 0.1 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AAS54223.1 - 0.21 11.4 4.2 9.1 6.2 0.0 2.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Glyco_transf_15 PF01793.11 AAS54224.1 - 2.2e-145 483.7 8.4 2.8e-145 483.4 5.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase MIP PF00230.15 AAS54225.2 - 1.9e-45 155.0 15.6 2.5e-45 154.7 10.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein ODC_AZ PF02100.12 AAS54226.2 - 2e-05 24.0 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme NUP PF06516.6 AAS54226.2 - 0.051 12.3 0.1 0.073 11.8 0.1 1.2 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) OrfB_Zn_ribbon PF07282.6 AAS54227.1 - 5.1e-17 61.2 1.7 1.2e-16 60.1 1.2 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.14 AAS54227.1 - 9.8e-12 44.7 1.7 2.2e-11 43.6 1.2 1.6 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.3 AAS54227.1 - 1.9e-08 33.5 0.0 3.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain IncA PF04156.9 AAS54227.1 - 0.12 11.9 1.7 0.22 11.0 1.2 1.4 1 0 0 1 1 1 0 IncA protein Exonuc_VII_L PF02601.10 AAS54227.1 - 0.29 10.2 3.3 0.63 9.1 2.3 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C2H2_6 PF13912.1 AAS54227.1 - 0.71 9.8 3.4 0.83 9.6 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger cwf21 PF08312.7 AAS54228.1 - 6.7e-14 51.4 10.4 1e-13 50.8 7.2 1.3 1 0 0 1 1 1 1 cwf21 domain AAA_13 PF13166.1 AAS54228.1 - 0.0094 14.4 1.0 0.01 14.3 0.7 1.0 1 0 0 1 1 1 1 AAA domain Tmemb_cc2 PF10267.4 AAS54228.1 - 0.015 13.8 1.2 0.016 13.8 0.9 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein LMP PF04778.7 AAS54228.1 - 0.029 14.1 0.1 0.042 13.5 0.1 1.3 1 1 0 1 1 1 0 LMP repeated region GreA_GreB_N PF03449.10 AAS54228.1 - 0.029 14.4 2.8 0.15 12.1 0.1 2.4 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal GvpG PF05120.7 AAS54228.1 - 0.047 13.4 1.6 0.08 12.7 1.1 1.3 1 0 0 1 1 1 0 Gas vesicle protein G IncA PF04156.9 AAS54228.1 - 0.11 12.0 4.3 0.13 11.8 3.0 1.2 1 0 0 1 1 1 0 IncA protein Trans_reg_C PF00486.23 AAS54228.1 - 0.14 12.0 0.9 0.44 10.4 0.6 1.9 1 1 0 1 1 1 0 Transcriptional regulatory protein, C terminal Cortex-I_coil PF09304.5 AAS54228.1 - 0.16 12.0 5.4 0.11 12.5 2.6 1.5 1 1 0 1 1 1 0 Cortexillin I, coiled coil Kinetocho_Slk19 PF12709.2 AAS54228.1 - 0.27 11.3 2.0 0.37 10.9 0.8 1.6 1 1 0 1 1 1 0 Central kinetochore-associated APG6 PF04111.7 AAS54228.1 - 0.28 10.2 3.0 0.31 10.0 2.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HR1 PF02185.11 AAS54228.1 - 0.29 10.9 3.0 1.3 8.7 0.1 2.4 1 1 1 2 2 2 0 Hr1 repeat Uds1 PF15456.1 AAS54228.1 - 1.1 9.3 7.6 1.5 8.8 5.3 1.3 1 0 0 1 1 1 0 Up-regulated During Septation Macoilin PF09726.4 AAS54228.1 - 1.4 7.1 7.1 1.7 6.8 4.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Acyl-CoA_dh_2 PF08028.6 AAS54228.1 - 7.1 6.8 9.9 5.1 7.3 5.8 1.5 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Striatin PF08232.7 AAS54228.1 - 8.9 6.6 8.8 1.1 9.5 2.6 1.8 1 1 1 2 2 2 0 Striatin family Arf PF00025.16 AAS54230.1 - 1.4e-46 157.9 0.1 1.8e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 AAS54230.1 - 1.7e-13 50.2 0.0 2.1e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS54230.1 - 3.7e-12 46.7 0.0 5.4e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 AAS54230.1 - 6.4e-11 41.5 0.0 1.1e-05 24.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 AAS54230.1 - 1.3e-10 40.7 0.0 1.6e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 AAS54230.1 - 2.2e-08 33.7 0.0 9e-07 28.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AAS54230.1 - 3.2e-06 26.4 0.0 3.8e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AAS54230.1 - 6e-05 22.9 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 AAS54230.1 - 0.024 14.7 0.0 0.12 12.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain HBS1_N PF08938.5 AAS54230.1 - 0.093 12.8 0.1 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 HBS1 N-terminus AAA_14 PF13173.1 AAS54230.1 - 0.099 12.5 0.0 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain Alk_phosphatase PF00245.15 AAS54231.1 - 5.3e-111 371.3 0.2 6.1e-111 371.0 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 AAS54231.1 - 0.003 17.0 0.0 0.0075 15.6 0.0 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily TPD PF14811.1 AAS54231.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif Anp1 PF03452.9 AAS54232.2 - 4.4e-105 350.6 0.0 5.4e-105 350.3 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 AAS54232.2 - 0.0021 17.7 0.0 0.028 14.0 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 2 GST_N PF02798.15 AAS54234.2 - 1.4e-08 34.7 0.0 4.7e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AAS54234.2 - 1.9e-08 34.0 6.3 4.6e-08 32.8 4.4 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AAS54234.2 - 1.2e-06 28.4 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 AAS54234.2 - 0.00038 20.6 0.0 0.0013 18.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 AAS54234.2 - 0.017 15.5 0.2 0.031 14.7 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Catalase PF00199.14 AAS54235.1 - 7.9e-172 571.2 1.1 1.1e-171 570.7 0.5 1.4 2 0 0 2 2 2 1 Catalase Catalase-rel PF06628.7 AAS54235.1 - 8.7e-12 44.7 0.1 3.7e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive Sgf11 PF08209.6 AAS54236.1 - 3e-17 61.6 4.0 4.5e-17 61.0 2.8 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-Di19 PF05605.7 AAS54236.1 - 0.036 14.1 0.2 0.061 13.4 0.1 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_UBOX PF13445.1 AAS54237.1 - 6.7e-14 51.3 4.0 1.6e-13 50.0 2.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 AAS54237.1 - 4.8e-10 39.2 0.7 7.6e-09 35.4 0.1 2.4 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_2 PF13639.1 AAS54237.1 - 0.0056 16.4 2.6 0.012 15.4 1.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AAS54237.1 - 0.098 12.4 2.9 0.23 11.2 2.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Skp1_POZ PF03931.10 AAS54238.1 - 4.2e-17 61.9 0.1 8.4e-17 61.0 0.0 1.5 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 AAS54238.1 - 0.0062 16.5 0.2 0.011 15.6 0.2 1.5 1 1 0 1 1 1 1 BTB/POZ domain Vps16_C PF04840.7 AAS54239.1 - 3.4e-71 239.8 5.8 6.3e-71 238.9 4.0 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 AAS54239.1 - 2.4e-61 207.4 0.0 3.5e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region CENP-N PF05238.8 AAS54240.2 - 1.5e-89 300.8 0.0 2e-89 300.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like RRM_1 PF00076.17 AAS54241.1 - 1.4e-57 191.2 1.0 8e-19 67.0 0.1 5.0 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS54241.1 - 2.1e-47 158.9 0.3 2.7e-14 52.8 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS54241.1 - 8.3e-22 76.7 0.0 2.2e-07 30.6 0.1 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 AAS54242.2 - 2.9e-55 187.2 0.3 1.8e-52 178.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AAS54242.2 - 5.6e-27 94.4 0.3 1e-24 87.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase FLILHELTA PF10306.4 AAS54243.1 - 3.4e-19 68.6 0.0 5.1e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA tRNA-synt_1 PF00133.17 AAS54244.1 - 2.8e-150 501.2 0.0 4.7e-150 500.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 AAS54244.1 - 3.1e-22 78.7 0.1 9.6e-12 44.2 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 AAS54244.1 - 3.8e-20 72.2 0.0 8e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 AAS54244.1 - 0.00014 21.3 3.0 0.0003 20.3 2.1 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 AAS54244.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 zf-C2H2_4 PF13894.1 AAS54245.1 - 2.9e-10 39.7 3.2 0.00062 19.9 0.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AAS54245.1 - 1.7e-08 34.3 6.1 0.0021 18.2 1.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AAS54245.1 - 0.0065 16.7 6.8 0.13 12.6 0.4 3.3 3 1 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 AAS54245.1 - 0.014 15.5 0.1 0.57 10.4 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AAS54245.1 - 0.02 15.0 0.4 0.53 10.5 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NAC PF01849.13 AAS54246.1 - 2.6e-16 58.8 0.1 4.4e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 NAC domain Glyco_hydro_20b PF02838.10 AAS54246.1 - 0.12 12.9 0.8 0.17 12.4 0.2 1.6 1 1 1 2 2 2 0 Glycosyl hydrolase family 20, domain 2 ApbA_C PF08546.6 AAS54247.1 - 4.4e-06 26.7 0.0 9.3e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal V-SNARE PF05008.10 AAS54247.1 - 4.6 7.4 8.4 4.8 7.4 1.3 2.9 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus F-box-like_2 PF13013.1 AAS54248.2 - 0.0032 17.1 0.0 0.016 14.9 0.0 2.1 1 1 0 1 1 1 1 F-box-like domain Pkinase PF00069.20 AAS54249.2 - 2.1e-72 243.4 0.0 2.4e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS54249.2 - 4.1e-36 124.3 0.0 7.8e-36 123.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS54249.2 - 0.00011 21.2 0.0 0.00019 20.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 AAS54249.2 - 0.0051 16.5 0.0 0.05 13.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family AdoMet_MTase PF07757.8 AAS54250.1 - 1.5e-41 141.0 0.1 2.3e-41 140.4 0.1 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 AAS54250.1 - 0.036 13.7 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 AAS54250.1 - 0.047 13.3 0.4 0.58 9.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 AAS54250.1 - 0.052 13.1 0.3 0.11 12.0 0.2 1.6 1 0 0 1 1 1 0 Methyltransferase domain SUV3_C PF12513.3 AAS54251.1 - 1.4e-15 56.4 3.9 4.1e-15 54.9 2.7 1.9 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 AAS54251.1 - 2.6e-14 52.8 0.0 5.7e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF866 PF05907.8 AAS54253.2 - 2.2e-24 85.7 6.8 1.1e-14 54.2 0.6 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) Lar_restr_allev PF14354.1 AAS54253.2 - 3.2 8.1 6.1 4.5 7.6 0.1 2.6 1 1 1 2 2 2 0 Restriction alleviation protein Lar Cofilin_ADF PF00241.15 AAS54254.1 - 5.4e-20 71.5 0.0 9.9e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.23 AAS54254.1 - 1.5e-17 62.7 0.9 2.9e-17 61.7 0.6 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AAS54254.1 - 5.4e-17 61.1 1.4 1.2e-16 60.0 0.5 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 AAS54254.1 - 1.8e-09 36.9 0.0 3.7e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain zf-LYAR PF08790.6 AAS54255.2 - 3e-14 52.3 7.2 5.9e-14 51.4 5.0 1.5 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger COX6B PF02297.12 AAS54255.2 - 0.031 14.3 3.3 0.056 13.4 2.3 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb IBR PF01485.16 AAS54255.2 - 0.52 10.2 6.3 0.91 9.4 4.3 1.5 1 0 0 1 1 1 0 IBR domain C1_4 PF07975.7 AAS54255.2 - 0.73 9.8 6.7 1.4 8.9 4.7 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain A2L_zn_ribbon PF08792.5 AAS54255.2 - 1.4 8.4 8.4 0.3 10.5 1.3 2.5 1 1 1 2 2 2 0 A2L zinc ribbon domain Tmemb_55A PF09788.4 AAS54255.2 - 6.5 5.8 7.0 0.9 8.6 1.2 1.9 2 0 0 2 2 2 0 Transmembrane protein 55A Csm1 PF12539.3 AAS54256.1 - 1.9e-32 111.5 0.0 3.1e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 CENP-Q PF13094.1 AAS54256.1 - 8.5e-05 22.6 7.2 0.00014 21.9 5.0 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Complex1_49kDa PF00346.14 AAS54256.1 - 0.0011 17.9 0.0 0.0022 17.0 0.0 1.4 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit GAS PF13851.1 AAS54256.1 - 0.0012 18.0 3.0 0.0019 17.4 2.1 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Filament PF00038.16 AAS54256.1 - 0.0015 18.0 3.0 0.002 17.6 2.1 1.2 1 0 0 1 1 1 1 Intermediate filament protein Herpes_ori_bp PF02399.10 AAS54256.1 - 0.0052 14.8 0.3 0.0071 14.3 0.2 1.0 1 0 0 1 1 1 1 Origin of replication binding protein TMF_DNA_bd PF12329.3 AAS54256.1 - 0.0092 15.7 5.9 0.015 15.0 4.1 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Myosin_tail_1 PF01576.14 AAS54256.1 - 0.0093 13.7 6.1 0.012 13.3 4.2 1.1 1 0 0 1 1 1 1 Myosin tail ATG16 PF08614.6 AAS54256.1 - 0.012 15.4 4.4 0.018 14.8 3.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.16 AAS54256.1 - 0.019 14.9 6.5 1 9.3 0.4 2.4 2 0 0 2 2 2 0 bZIP transcription factor IncA PF04156.9 AAS54256.1 - 0.027 14.0 5.1 0.054 13.0 3.5 1.5 1 0 0 1 1 1 0 IncA protein Tektin PF03148.9 AAS54256.1 - 0.03 12.8 4.7 0.042 12.4 3.3 1.2 1 0 0 1 1 1 0 Tektin family Lebercilin PF15619.1 AAS54256.1 - 0.04 13.3 5.7 0.016 14.6 2.3 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4201 PF13870.1 AAS54256.1 - 0.056 12.8 3.2 0.083 12.3 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF972 PF06156.8 AAS54256.1 - 0.091 13.1 0.7 0.14 12.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 AAS54256.1 - 0.13 11.7 2.5 0.21 11.0 1.7 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 APG6 PF04111.7 AAS54256.1 - 0.14 11.2 4.1 0.19 10.7 2.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Kinesin-relat_1 PF12711.2 AAS54256.1 - 0.18 12.1 4.7 0.14 12.5 0.6 2.3 3 0 0 3 3 2 0 Kinesin motor Flagellin_N PF00669.15 AAS54256.1 - 0.35 10.6 3.1 8.4 6.1 0.7 2.1 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region DUF3584 PF12128.3 AAS54256.1 - 0.38 8.0 6.4 0.48 7.6 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.3 AAS54256.1 - 1.5 8.6 7.5 2.7 7.8 5.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.3 AAS54256.1 - 2 7.6 9.1 0.34 10.1 3.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Sec2p PF06428.6 AAS54256.1 - 8.5 6.2 12.6 1.6 8.6 2.0 2.6 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p WD40 PF00400.27 AAS54257.1 - 2.8e-63 207.7 14.2 6.4e-10 38.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 AAS54257.1 - 6.2e-31 106.4 14.6 9.8e-31 105.7 10.1 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 AAS54257.1 - 1e-06 27.2 3.7 0.13 10.4 0.1 4.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AAS54257.1 - 0.0018 17.1 0.1 2.4 6.8 0.0 3.2 1 1 3 4 4 4 2 Nup133 N terminal like Phage_lysis PF03245.8 AAS54257.1 - 0.0096 15.9 2.4 0.023 14.6 1.7 1.6 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein NIT PF08376.5 AAS54257.1 - 0.031 13.8 6.2 0.043 13.3 4.3 1.2 1 0 0 1 1 1 0 Nitrate and nitrite sensing Cytochrom_D1 PF02239.11 AAS54257.1 - 0.041 12.1 0.2 2.7 6.2 0.0 2.6 1 1 1 2 2 2 0 Cytochrome D1 heme domain FimP PF09766.4 AAS54257.1 - 0.14 11.2 7.4 0.23 10.5 5.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein COMP PF11598.3 AAS54257.1 - 0.16 12.0 0.4 0.34 11.0 0.3 1.5 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein DUF342 PF03961.8 AAS54257.1 - 2.2 6.6 4.4 2.9 6.1 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FlxA PF14282.1 AAS54257.1 - 7.5 6.5 11.4 23 5.0 7.9 1.7 1 1 0 1 1 1 0 FlxA-like protein Zn_clus PF00172.13 AAS54258.1 - 3.9e-08 33.0 8.6 6e-08 32.4 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GHMP_kinases_N PF00288.21 AAS54259.2 - 5.6e-11 42.3 1.0 2e-10 40.5 0.7 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain UbiA PF01040.13 AAS54260.1 - 1.5e-32 112.8 23.6 2.1e-32 112.3 16.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Thioredoxin PF00085.15 AAS54262.1 - 4.3e-22 77.7 0.0 5.1e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AAS54262.1 - 8.4e-07 29.1 0.0 8.2e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 AAS54262.1 - 2.4e-05 23.8 0.0 3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AAS54262.1 - 3.8e-05 23.7 0.0 0.029 14.4 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like DSBA PF01323.15 AAS54262.1 - 6.9e-05 22.4 0.0 0.00015 21.3 0.0 1.6 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_7 PF13899.1 AAS54262.1 - 0.0013 18.7 0.1 0.0032 17.4 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like TrbC_Ftype PF09673.5 AAS54262.1 - 0.0054 16.3 0.0 0.0064 16.0 0.0 1.3 1 1 0 1 1 1 1 Type-F conjugative transfer system pilin assembly protein Redoxin PF08534.5 AAS54262.1 - 0.0069 15.9 0.0 0.025 14.1 0.0 1.7 1 1 1 2 2 2 1 Redoxin Thioredoxin_3 PF13192.1 AAS54262.1 - 0.041 13.7 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain TraF PF13728.1 AAS54262.1 - 0.097 12.1 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Cation_efflux PF01545.16 AAS54264.2 - 1.3e-05 24.3 12.0 6.8e-05 22.0 7.5 2.6 2 1 0 2 2 2 1 Cation efflux family Med12 PF09497.5 AAS54265.2 - 2.5e-26 91.4 0.2 5.6e-26 90.3 0.1 1.6 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 DEAD PF00270.24 AAS54266.1 - 2.4e-36 124.7 0.3 4.6e-36 123.8 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS54266.1 - 3.9e-18 65.0 0.1 9.6e-18 63.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS54266.1 - 8.7e-08 32.2 0.6 3.6e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 AAS54266.1 - 2.7e-07 29.7 0.1 5.2e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.4 AAS54266.1 - 0.0011 17.9 0.0 0.0023 16.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 AAS54266.1 - 0.0023 17.6 0.1 0.0058 16.2 0.0 1.7 2 0 0 2 2 2 1 Helicase Flavi_DEAD PF07652.9 AAS54266.1 - 0.0029 17.3 0.6 0.014 15.1 0.2 2.2 1 1 1 2 2 2 1 Flavivirus DEAD domain AAA_22 PF13401.1 AAS54266.1 - 0.016 15.3 0.2 0.071 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 AAS54266.1 - 0.025 13.8 0.0 0.045 13.0 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Ribosomal_S19 PF00203.16 AAS54267.1 - 2e-22 78.5 0.0 2.6e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 PP2C PF00481.16 AAS54268.1 - 1.9e-29 102.8 0.0 7.7e-27 94.3 0.0 2.4 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 AAS54268.1 - 0.0018 17.7 0.0 0.0049 16.2 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 AAS54268.1 - 0.076 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Ribosom_S12_S23 PF00164.20 AAS54269.1 - 2.6e-45 152.7 1.6 3.2e-45 152.5 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 P34-Arc PF04045.9 AAS54270.1 - 6.8e-95 316.9 0.5 8.5e-95 316.6 0.4 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc PAT1 PF09770.4 AAS54271.1 - 9.5e-265 880.8 7.0 1.9e-264 879.7 4.8 1.4 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 LRR_4 PF12799.2 AAS54272.2 - 0.014 15.0 0.1 2.5 7.8 0.0 4.1 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Slx4 PF09494.5 AAS54272.2 - 0.092 12.5 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Slx4 endonuclease Clathrin PF00637.15 AAS54273.1 - 0.0027 17.3 0.9 0.17 11.5 0.0 3.9 3 1 1 4 4 4 1 Region in Clathrin and VPS CBFD_NFYB_HMF PF00808.18 AAS54273.1 - 0.041 13.9 0.1 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-C3HC4_4 PF15227.1 AAS54274.2 - 2.1e-09 37.1 10.2 2.1e-09 37.1 7.1 2.3 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 AAS54274.2 - 4.2e-09 35.9 9.6 4.2e-09 35.9 6.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS54274.2 - 7.3e-08 32.3 9.6 7.3e-08 32.3 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AAS54274.2 - 2.2e-07 30.4 6.5 2.2e-07 30.4 4.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AAS54274.2 - 3e-07 30.1 9.1 3e-07 30.1 6.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 AAS54274.2 - 4.8e-06 26.1 1.6 1e-05 25.1 1.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 AAS54274.2 - 4.1e-05 23.6 11.0 0.00025 21.0 3.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 AAS54274.2 - 0.00013 21.5 8.3 0.00013 21.5 5.8 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 AAS54274.2 - 0.00049 19.8 2.3 0.00049 19.8 1.6 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger PolC_DP2 PF03833.8 AAS54274.2 - 0.00053 17.8 3.2 0.091 10.4 0.2 2.1 2 0 0 2 2 2 2 DNA polymerase II large subunit DP2 zf-RING_6 PF14835.1 AAS54274.2 - 0.0041 16.8 8.6 0.046 13.4 1.7 2.3 2 0 0 2 2 2 2 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 AAS54274.2 - 0.0044 16.5 2.3 0.0044 16.5 1.6 3.0 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain SPT6_acidic PF14632.1 AAS54274.2 - 0.046 13.8 11.4 0.21 11.7 0.3 2.9 3 1 0 3 3 2 0 Acidic N-terminal SPT6 Ogr_Delta PF04606.7 AAS54274.2 - 0.2 11.3 0.1 0.2 11.3 0.1 3.6 4 0 0 4 4 4 0 Ogr/Delta-like zinc finger DZR PF12773.2 AAS54274.2 - 0.5 10.2 11.7 0.69 9.7 0.6 2.6 2 1 0 2 2 2 0 Double zinc ribbon Baculo_IE-1 PF05290.6 AAS54274.2 - 2.3 7.9 9.3 0.17 11.6 2.7 1.9 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) HypA PF01155.14 AAS54274.2 - 2.4 7.8 8.6 0.82 9.3 0.5 2.3 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family RecR PF02132.10 AAS54274.2 - 2.4 7.6 10.8 0.94 8.9 0.5 3.5 3 0 0 3 3 3 0 RecR protein zinc-ribbons_6 PF07191.7 AAS54274.2 - 8.5 6.2 12.1 2.1 8.1 0.3 3.0 2 1 0 3 3 3 0 zinc-ribbons zinc_ribbon_2 PF13240.1 AAS54274.2 - 8.6 5.9 8.9 39 3.9 0.4 3.5 2 1 2 4 4 4 0 zinc-ribbon domain DUF2982 PF11201.3 AAS54277.2 - 0.15 11.4 0.2 0.2 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) SNF2_N PF00176.18 AAS54279.2 - 3.3e-60 203.4 0.0 4.9e-60 202.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AAS54279.2 - 2.5e-12 46.4 0.0 5.4e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 AAS54279.2 - 1.4e-10 40.4 0.6 1.5e-09 37.1 0.4 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 AAS54279.2 - 1.8e-08 34.4 0.0 6e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AAS54279.2 - 2.4e-08 33.6 0.1 1.2e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 AAS54279.2 - 0.017 14.0 0.0 0.039 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF2439 PF10382.4 AAS54279.2 - 0.07 13.3 0.2 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) Ank_5 PF13857.1 AAS54280.1 - 3.7e-06 26.9 0.2 8.8e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AKAP95 PF04988.7 AAS54280.1 - 0.00028 20.6 0.2 0.0026 17.5 0.0 2.4 2 0 0 2 2 2 1 A-kinase anchoring protein 95 (AKAP95) PAS_7 PF12860.2 AAS54280.1 - 0.051 13.5 1.6 0.11 12.4 0.1 2.2 2 0 0 2 2 2 0 PAS fold Ank PF00023.25 AAS54280.1 - 0.068 13.0 0.6 0.16 11.8 0.4 1.7 1 0 0 1 1 1 0 Ankyrin repeat zf-C2H2_jaz PF12171.3 AAS54280.1 - 0.085 13.0 0.9 0.26 11.4 0.6 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding URO-D PF01208.12 AAS54281.1 - 5.7e-124 413.5 0.0 6.4e-124 413.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Peptidase_M28 PF04389.12 AAS54282.1 - 2.2e-30 105.6 0.0 2.2e-30 105.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 AAS54282.1 - 0.00025 20.5 0.0 0.0004 19.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 AAS54282.1 - 0.0041 15.9 0.0 0.0097 14.6 0.0 1.5 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Glyco_hydro_81 PF03639.8 AAS54283.2 - 8.4e-225 747.9 7.9 9.6e-225 747.7 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 zf-C2H2 PF00096.21 AAS54284.1 - 3e-11 42.9 8.4 2.2e-05 24.5 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AAS54284.1 - 8.7e-07 28.9 12.6 1.7e-06 28.0 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AAS54284.1 - 4.9e-05 23.3 10.4 0.0051 17.0 0.2 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AAS54284.1 - 0.0057 16.7 4.3 0.0087 16.1 0.0 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AAS54284.1 - 0.018 14.9 6.4 0.57 10.1 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 AAS54284.1 - 0.29 11.1 3.0 4.9 7.1 0.6 2.5 1 1 1 2 2 2 0 Zinc ribbon domain zf-met PF12874.2 AAS54284.1 - 0.36 11.1 2.4 2.9 8.2 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Fungal_trans_2 PF11951.3 AAS54285.2 - 2e-11 43.1 0.1 7.4e-10 37.9 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS54285.2 - 2.2e-05 24.2 8.4 4.8e-05 23.1 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dfp1_Him1_M PF08630.5 AAS54286.1 - 4.9e-47 158.7 0.0 1.5e-46 157.2 0.0 1.9 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 AAS54286.1 - 3.4e-21 74.6 0.9 6.4e-21 73.7 0.6 1.4 1 0 0 1 1 1 1 DBF zinc finger UQ_con PF00179.21 AAS54288.1 - 9e-45 151.5 0.0 1.2e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AAS54288.1 - 0.0033 17.1 0.0 0.012 15.3 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B AMNp_N PF10423.4 AAS54288.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus NOA36 PF06524.7 AAS54288.1 - 3.5 6.7 14.7 4.8 6.3 10.2 1.1 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.7 AAS54288.1 - 8.1 5.4 17.2 11 5.0 11.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Alg14 PF08660.6 AAS54289.1 - 4.4e-51 173.2 0.0 5.6e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TIM PF00121.13 AAS54290.2 - 5.4e-90 300.7 0.0 6e-90 300.5 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase AP_endonuc_2 PF01261.19 AAS54290.2 - 0.061 12.6 0.1 0.099 11.9 0.1 1.6 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel 2-oxoacid_dh PF00198.18 AAS54291.1 - 3.1e-78 262.2 0.1 4.8e-78 261.6 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 AAS54291.1 - 1.6e-16 59.6 0.6 3e-16 58.8 0.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.14 AAS54291.1 - 9.4e-05 22.0 0.2 0.00019 21.0 0.2 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.1 AAS54291.1 - 0.00024 21.3 0.3 0.0025 18.1 0.0 2.3 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 AAS54291.1 - 0.00066 19.2 0.1 0.0043 16.6 0.1 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD PF00529.15 AAS54291.1 - 0.0015 17.9 8.4 0.0028 17.0 4.9 1.9 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 AAS54291.1 - 0.0034 17.0 0.0 0.017 14.7 0.0 2.2 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.4 AAS54291.1 - 0.054 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DUF2360 PF10152.4 AAS54291.1 - 0.93 9.7 5.8 1.9 8.7 4.0 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Choline_kinase PF01633.15 AAS54292.1 - 7.4e-63 211.9 0.0 9.8e-63 211.5 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 AAS54292.1 - 3.4e-13 49.8 0.0 4.1e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kin_N PF04428.9 AAS54292.1 - 3.7e-12 45.5 0.0 9.1e-12 44.2 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus HVSL PF09749.4 AAS54293.1 - 2.6e-12 46.2 0.0 3.3e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein zf-C2H2 PF00096.21 AAS54294.1 - 4.8e-08 32.8 17.7 0.0038 17.4 0.5 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS54294.1 - 2.8e-05 24.1 13.9 0.026 14.8 0.6 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AAS54294.1 - 0.0002 21.4 15.2 0.0068 16.6 0.3 3.6 3 0 0 3 3 3 2 Zinc-finger double domain Suf PF05843.9 AAS54294.1 - 0.06 13.0 5.4 0.16 11.6 3.8 1.7 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-C2H2_6 PF13912.1 AAS54294.1 - 0.27 11.1 7.8 0.61 10.0 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger WD40 PF00400.27 AAS54295.2 - 1.9e-70 230.4 25.3 1.3e-09 37.5 0.1 11.3 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 AAS54295.2 - 1.1e-22 79.9 0.7 2.2e-22 79.0 0.5 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 AAS54295.2 - 1e-07 30.5 10.6 0.015 13.4 0.1 5.8 4 2 1 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.6 AAS54295.2 - 9.1e-05 22.2 0.4 3.5 7.2 0.0 4.1 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 AAS54295.2 - 0.00043 19.5 2.9 1.4 8.0 0.0 4.8 5 0 0 5 5 5 1 TUP1-like enhancer of split Cytochrom_D1 PF02239.11 AAS54295.2 - 0.0079 14.5 0.1 4.3 5.5 0.1 3.2 3 1 1 4 4 4 2 Cytochrome D1 heme domain TFIID_20kDa PF03847.8 AAS54296.1 - 2.3e-32 111.0 0.6 4.7e-32 110.0 0.4 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 AAS54296.1 - 0.003 17.6 0.0 0.0097 16.0 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Seryl_tRNA_N PF02403.17 AAS54296.1 - 0.013 15.5 3.0 0.049 13.6 2.1 2.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 AAS54296.1 - 0.041 12.3 3.4 0.073 11.4 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) K-box PF01486.12 AAS54296.1 - 0.065 13.0 1.6 0.16 11.7 1.1 1.7 1 0 0 1 1 1 0 K-box region CBFD_NFYB_HMF PF00808.18 AAS54296.1 - 0.086 12.9 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ATP-synt_E_2 PF08112.6 AAS54296.1 - 0.4 10.7 3.4 18 5.4 0.5 2.5 2 0 0 2 2 2 0 ATP synthase epsilon subunit CENP-F_leu_zip PF10473.4 AAS54296.1 - 0.88 9.4 5.9 0.76 9.6 2.8 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cullin_binding PF03556.10 AAS54297.2 - 3.3e-30 104.6 0.3 8.4e-30 103.3 0.0 1.7 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 AAS54297.2 - 1.5e-10 40.4 0.1 3.7e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain Cullin PF00888.17 AAS54298.1 - 2.1e-17 62.9 2.0 4.8e-17 61.7 0.4 2.0 2 0 0 2 2 2 1 Cullin family Asp PF00026.18 AAS54299.2 - 7.1e-70 235.7 0.0 8.8e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AAS54299.2 - 1.4e-09 38.1 0.1 4.1e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AAS54299.2 - 0.0023 18.3 0.0 2.5 8.6 0.0 3.4 3 0 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 AAS54299.2 - 0.044 13.3 0.0 0.41 10.1 0.0 2.4 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 AAS54299.2 - 0.056 13.2 0.2 7.9 6.3 0.0 2.7 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease zf-RING_2 PF13639.1 AAS54300.2 - 4.7e-12 45.5 7.8 6.3e-11 41.9 2.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 AAS54300.2 - 3.3e-07 30.2 3.2 8e-06 25.8 1.3 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AAS54300.2 - 1.8e-06 27.8 7.3 1.6e-05 24.7 2.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AAS54300.2 - 7.8e-06 25.4 5.3 1.2e-05 24.8 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AAS54300.2 - 1.6e-05 24.4 4.0 4e-05 23.1 1.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AAS54300.2 - 8.1e-05 22.2 0.3 8.1e-05 22.2 0.2 2.5 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AAS54300.2 - 0.00013 21.7 4.2 0.00014 21.6 1.1 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 AAS54300.2 - 0.00063 19.4 4.6 0.0009 18.9 1.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 AAS54300.2 - 0.0046 16.4 2.3 0.011 15.2 1.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 AAS54300.2 - 0.029 14.2 1.4 0.045 13.5 0.2 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 AAS54300.2 - 0.38 10.3 4.3 0.62 9.7 1.1 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 AAS54300.2 - 0.44 10.1 1.9 0.81 9.2 1.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit WD40 PF00400.27 AAS54301.1 - 3.8e-25 86.7 17.3 1e-05 25.1 0.3 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Mod_r PF07200.8 AAS54302.1 - 1.6e-22 80.0 4.8 2e-22 79.7 3.3 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein ATG16 PF08614.6 AAS54302.1 - 0.0048 16.7 1.6 0.011 15.6 0.2 1.9 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF4164 PF13747.1 AAS54302.1 - 0.014 15.5 6.8 0.45 10.6 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF607 PF04678.8 AAS54302.1 - 0.041 13.8 0.6 0.057 13.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF607 DUF4201 PF13870.1 AAS54302.1 - 0.046 13.1 6.3 1.1 8.6 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Pil1 PF13805.1 AAS54302.1 - 0.11 11.5 2.7 1.1 8.3 1.8 1.9 1 1 0 1 1 1 0 Eisosome component PIL1 TPR_MLP1_2 PF07926.7 AAS54302.1 - 0.12 12.1 5.0 0.38 10.4 3.5 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein KNOX2 PF03791.8 AAS54302.1 - 0.23 10.7 1.6 0.44 9.8 0.0 2.3 2 1 1 3 3 3 0 KNOX2 domain Tup_N PF08581.5 AAS54302.1 - 0.33 11.1 4.8 0.4 10.9 1.1 2.4 2 1 0 2 2 2 0 Tup N-terminal zf-HC2 PF13490.1 AAS54302.1 - 0.38 10.7 4.1 1.7 8.6 0.0 3.7 3 1 0 3 3 3 0 Putative zinc-finger FadA PF09403.5 AAS54302.1 - 1.2 9.1 6.7 2.5 8.1 1.7 2.1 1 1 1 2 2 2 0 Adhesion protein FadA Mnd1 PF03962.10 AAS54302.1 - 2 8.0 9.5 11 5.5 3.1 2.0 1 1 1 2 2 2 0 Mnd1 family DUF4140 PF13600.1 AAS54302.1 - 2.7 8.4 8.6 2.1 8.8 1.4 2.6 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Abhydrolase_2 PF02230.11 AAS54303.1 - 3.6e-46 157.3 0.0 4.3e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 AAS54303.1 - 5.2e-13 48.9 0.1 6.4e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AAS54303.1 - 1.6e-07 31.4 0.7 7.2e-07 29.3 0.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 AAS54303.1 - 4.3e-07 29.5 0.0 8.7e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 AAS54303.1 - 2e-05 23.9 0.1 6.6e-05 22.2 0.0 1.8 2 1 1 3 3 3 1 Dienelactone hydrolase family Cutinase PF01083.17 AAS54303.1 - 0.17 11.5 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase Dopey_N PF04118.9 AAS54304.2 - 1.2e-118 395.3 3.7 1.2e-118 395.3 0.7 2.4 2 0 0 2 2 2 1 Dopey, N-terminal Methyltransf_26 PF13659.1 AAS54305.1 - 6.2e-16 58.4 0.5 8.6e-16 58.0 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AAS54305.1 - 5.9e-11 42.0 0.0 7.3e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 AAS54305.1 - 0.0001 22.6 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AAS54305.1 - 0.00016 22.0 0.1 0.00038 20.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS54305.1 - 0.00081 19.0 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AAS54305.1 - 0.0059 17.0 0.0 0.0099 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AAS54305.1 - 0.017 14.2 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 AAS54305.1 - 0.037 14.6 0.0 0.051 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 AAS54305.1 - 0.072 12.8 0.0 0.19 11.4 0.0 1.8 1 1 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 AAS54305.1 - 0.16 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase ubiquitin PF00240.18 AAS54306.2 - 2.3e-22 78.1 0.4 2.6e-22 78.0 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AAS54306.2 - 2.1e-16 59.3 0.3 2.3e-16 59.2 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AAS54306.2 - 0.001 19.2 0.1 0.0026 17.9 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain TUG-UBL1 PF11470.3 AAS54306.2 - 0.085 12.7 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG HAT PF02184.11 AAS54307.1 - 1.9e-19 69.0 34.1 2.2e-05 24.1 1.6 9.0 9 1 0 9 9 9 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 AAS54307.1 - 7.6e-16 57.1 23.1 0.00014 22.2 0.4 10.3 5 3 6 11 11 11 5 Tetratricopeptide repeat Suf PF05843.9 AAS54307.1 - 1.5e-14 54.4 8.1 3.6e-07 30.1 0.0 5.2 3 2 2 5 5 5 4 Suppressor of forked protein (Suf) TPR_16 PF13432.1 AAS54307.1 - 9.9e-10 38.8 25.4 2.4e-06 28.0 1.6 7.6 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 AAS54307.1 - 5.2e-09 36.3 2.0 0.00043 20.5 0.0 4.8 3 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 AAS54307.1 - 6.8e-05 22.7 0.4 0.61 10.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 AAS54307.1 - 0.00031 20.6 6.6 2.7 8.0 0.2 5.0 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 AAS54307.1 - 0.0071 15.9 3.3 0.47 10.1 0.0 4.5 5 0 0 5 5 5 1 TPR repeat U3_assoc_6 PF08640.6 AAS54307.1 - 0.011 15.4 3.5 0.011 15.4 2.4 5.6 6 2 2 8 8 8 0 U3 small nucleolar RNA-associated protein 6 TPR_2 PF07719.12 AAS54307.1 - 0.12 12.3 13.7 0.63 10.1 0.0 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 AAS54307.1 - 2.3 8.2 13.5 1.8 8.5 0.0 6.0 8 0 0 8 8 8 0 Tetratricopeptide repeat KH_3 PF13014.1 AAS54308.2 - 1.6e-06 27.6 0.1 3.9e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 KH domain KH_1 PF00013.24 AAS54308.2 - 2.2e-06 27.2 0.0 4.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.18 AAS54308.2 - 1.4e-05 24.7 8.3 9.4e-05 22.1 0.4 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 AAS54308.2 - 0.047 13.4 0.4 0.047 13.4 0.3 2.4 1 1 1 2 2 2 0 Zinc knuckle Lar_restr_allev PF14354.1 AAS54308.2 - 0.18 12.1 2.5 0.35 11.2 1.7 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-CCHC_5 PF14787.1 AAS54308.2 - 1.9 8.0 6.3 1.5 8.3 0.1 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger CPSF100_C PF13299.1 AAS54309.2 - 4.8e-31 108.1 3.3 2.1e-29 102.7 0.2 3.0 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 AAS54309.2 - 2.6e-12 46.8 0.5 7.9e-12 45.2 0.0 2.1 3 0 0 3 3 3 1 Beta-Casp domain efThoc1 PF11957.3 AAS54310.1 - 1.5e-117 393.1 0.0 2.2e-117 392.5 0.0 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Avl9 PF09794.4 AAS54311.1 - 1e-149 498.1 0.6 1.3e-149 497.8 0.4 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 AAS54311.1 - 2.1e-07 30.4 0.6 7.7e-06 25.3 0.4 2.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 AAS54311.1 - 2.8e-07 30.2 0.1 0.0049 16.5 0.0 2.9 3 0 0 3 3 3 2 Stabilization of polarity axis DENN PF02141.16 AAS54311.1 - 0.00089 19.0 0.9 0.15 11.7 0.5 2.6 2 1 0 2 2 2 1 DENN (AEX-3) domain Afi1 PF07792.7 AAS54311.1 - 0.0064 16.5 0.0 0.025 14.6 0.0 1.9 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Rgp1 PF08737.5 AAS54312.1 - 5.7e-93 312.2 3.0 9.3e-93 311.5 2.1 1.3 1 0 0 1 1 1 1 Rgp1 U-box PF04564.10 AAS54312.1 - 0.081 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 U-box domain RVT_1 PF00078.22 AAS54313.1 - 5.5e-12 45.5 0.0 1.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 AAS54313.1 - 2.6e-08 33.8 0.0 7e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Pro_isomerase PF00160.16 AAS54314.1 - 1.7e-47 161.5 0.1 1.9e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 AAS54314.1 - 0.078 12.8 0.2 0.71 9.7 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain RNA_polI_A14 PF08203.6 AAS54315.1 - 3.2e-23 81.7 0.1 1e-22 80.1 0.0 1.8 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 YPEB PF14620.1 AAS54315.1 - 0.069 12.1 0.1 0.086 11.8 0.0 1.1 1 0 0 1 1 1 0 YpeB sporulation Semialdhyde_dhC PF02774.13 AAS54316.1 - 2.3e-43 148.2 0.0 3.4e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 AAS54316.1 - 6.3e-30 103.9 0.0 1.2e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 AAS54316.1 - 0.019 15.5 0.0 0.059 13.8 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Saccharop_dh PF03435.13 AAS54316.1 - 0.02 13.8 0.2 0.034 13.1 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase DapB_N PF01113.15 AAS54316.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 AAS54316.1 - 0.25 11.3 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding Methyltransf_16 PF10294.4 AAS54317.1 - 2.3e-05 23.8 0.0 0.043 13.2 0.0 2.2 1 1 1 2 2 2 2 Putative methyltransferase DDOST_48kD PF03345.9 AAS54317.1 - 0.096 11.1 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta SAC3_GANP PF03399.11 AAS54318.1 - 8e-55 185.5 0.7 1.6e-54 184.5 0.5 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SAC3 PF12209.3 AAS54318.1 - 2.5e-25 88.3 3.2 6.8e-25 87.0 2.2 1.8 1 0 0 1 1 1 1 Leucine permease transcriptional regulator helical domain Nha1_C PF08619.5 AAS54319.2 - 8.3e-89 298.8 17.5 1.1e-88 298.4 12.1 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 AAS54319.2 - 4.4e-78 262.4 25.2 5.3e-78 262.2 17.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family AA_permease PF00324.16 AAS54320.2 - 3.4e-70 236.7 41.3 5.7e-70 235.9 28.7 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS54320.2 - 3.5e-27 95.0 44.0 1e-26 93.4 30.4 1.8 1 1 0 1 1 1 1 Amino acid permease TPR_2 PF07719.12 AAS54321.1 - 3.4e-09 35.9 3.8 0.01 15.6 0.3 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 AAS54321.1 - 4.9e-08 32.5 5.5 0.0073 15.9 0.0 4.1 3 1 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 AAS54321.1 - 7.1e-07 29.0 1.6 0.034 14.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 AAS54321.1 - 1.2e-06 27.9 1.4 0.31 10.9 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AAS54321.1 - 1.2e-06 28.6 6.8 0.0066 16.9 0.1 5.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 AAS54321.1 - 4.1e-06 26.1 0.1 0.082 12.7 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 AAS54321.1 - 7.8e-05 22.1 6.5 0.49 10.0 0.4 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 AAS54321.1 - 0.00013 22.5 5.4 1.7 9.4 0.1 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 AAS54321.1 - 0.00035 20.8 14.6 0.01 16.1 0.3 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 AAS54321.1 - 0.17 12.4 0.7 11 6.7 0.0 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SH3_9 PF14604.1 AAS54322.2 - 5.5e-12 45.0 0.1 1.2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AAS54322.2 - 9.4e-11 40.9 0.0 2e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AAS54322.2 - 2.6e-06 26.8 0.0 5.6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Cwf_Cwc_15 PF04889.7 AAS54323.1 - 1.1e-16 61.2 14.4 6.9e-08 32.5 0.4 3.0 2 1 1 3 3 3 3 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.9 AAS54323.1 - 0.12 11.9 1.3 0.18 11.2 0.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.7 AAS54323.1 - 0.42 9.8 5.2 0.65 9.1 3.6 1.3 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 AAS54323.1 - 0.71 7.8 7.2 0.9 7.4 5.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Atrophin-1 PF03154.10 AAS54323.1 - 0.72 7.9 5.7 0.96 7.5 3.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family Nop14 PF04147.7 AAS54323.1 - 3.4 5.4 7.6 3.7 5.3 5.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4407 PF14362.1 AAS54323.1 - 3.9 6.3 7.8 4.9 6.0 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SLS PF14611.1 AAS54324.2 - 1.5e-26 93.1 0.7 2.4e-26 92.4 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Pro_dh PF01619.13 AAS54326.1 - 1.4e-55 188.5 0.0 1.8e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase ATP_bind_4 PF01902.12 AAS54327.1 - 3.2e-35 121.4 0.0 1.4e-34 119.3 0.0 1.9 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 AAS54327.1 - 8.2e-15 54.6 0.0 3.6e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 Endoribonuclease L-PSP Sec1 PF00995.18 AAS54329.1 - 6.2e-93 312.3 0.8 7.2e-93 312.1 0.6 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_hydro_81 PF03639.8 AAS54330.1 - 9.1e-231 767.6 5.8 1e-230 767.4 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 DUF4477 PF14780.1 AAS54331.1 - 0.00027 20.3 2.3 0.12 11.6 0.1 2.3 1 1 0 2 2 2 2 Domain of unknown function (DUF4477) UPF0060 PF02694.10 AAS54331.1 - 0.024 14.6 0.2 0.039 13.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family CPSF_A PF03178.10 AAS54332.1 - 0.00024 20.2 0.0 0.0041 16.2 0.0 2.6 2 2 0 2 2 2 1 CPSF A subunit region WD40 PF00400.27 AAS54332.1 - 0.00083 19.1 1.0 2.1 8.3 0.2 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat MOFRL PF05161.8 AAS54332.1 - 0.037 14.1 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 MOFRL family Sec5 PF15469.1 AAS54333.1 - 1.4e-52 178.1 4.9 1.4e-52 178.1 3.4 2.5 3 0 0 3 3 3 1 Exocyst complex component Sec5 Rapamycin_bind PF08771.6 AAS54333.1 - 0.027 14.5 2.0 0.11 12.6 0.2 2.9 2 0 0 2 2 2 0 Rapamycin binding domain DUF1512 PF07431.7 AAS54333.1 - 0.037 12.7 1.6 0.064 11.9 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) Orthopox_A49R PF06489.6 AAS54333.1 - 0.1 12.5 8.0 0.42 10.5 0.5 3.5 2 1 1 3 3 3 0 Orthopoxvirus A49R protein Antimicrobial15 PF08110.7 AAS54333.1 - 1.5 8.9 3.1 2.3 8.4 0.1 2.5 2 0 0 2 2 2 0 Ocellatin family LSM PF01423.17 AAS54334.1 - 1.1e-15 56.9 0.1 1.3e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain Tail_tube PF10618.4 AAS54334.1 - 0.0028 17.3 0.1 0.023 14.4 0.0 2.0 1 1 1 2 2 2 1 Phage tail tube protein SM-ATX PF14438.1 AAS54334.1 - 0.072 13.0 0.2 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 Ataxin 2 SM domain Pep3_Vps18 PF05131.9 AAS54335.1 - 4.6e-40 136.4 0.0 1.1e-39 135.2 0.0 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 AAS54335.1 - 1.4e-06 27.9 1.2 1.4e-06 27.9 0.8 3.1 3 1 0 3 3 3 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 AAS54335.1 - 0.00039 20.1 3.7 0.00096 18.9 2.6 1.7 1 0 0 1 1 1 1 Ring finger domain Vps39_2 PF10367.4 AAS54335.1 - 0.00044 20.3 0.3 0.00044 20.3 0.2 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.20 AAS54335.1 - 0.0024 17.5 1.5 0.0089 15.6 1.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AAS54335.1 - 0.013 15.1 7.8 0.044 13.5 5.4 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AAS54335.1 - 0.013 15.4 1.0 0.013 15.4 0.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ACCA PF03255.9 AAS54335.1 - 0.42 10.1 2.5 2.1 7.8 0.5 2.5 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TFIID_30kDa PF03540.8 AAS54336.1 - 2.6e-28 97.5 0.1 7.1e-28 96.1 0.1 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 AAS54336.1 - 0.053 13.2 0.3 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 Bromodomain associated CDC37_N PF03234.9 AAS54337.1 - 2.6e-70 236.3 14.0 2.6e-70 236.3 9.7 2.8 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 AAS54337.1 - 9.1e-54 181.5 1.7 9.1e-54 181.5 1.2 2.9 3 0 0 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 AAS54337.1 - 4.5e-27 93.8 4.6 4.5e-27 93.8 3.2 2.3 2 0 0 2 2 2 1 Cdc37 C terminal domain DUF883 PF05957.8 AAS54337.1 - 5 7.5 6.0 34 4.9 1.0 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2415 PF10313.4 AAS54338.1 - 3.8e-20 71.2 1.9 9.4e-20 70.0 1.3 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Stb3 PF10330.4 AAS54339.1 - 3.2e-33 113.2 0.1 6.3e-33 112.3 0.1 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein MarB PF13999.1 AAS54339.1 - 0.005 16.3 0.7 0.016 14.7 0.5 1.9 1 0 0 1 1 1 1 MarB protein Stm1_N PF09598.5 AAS54340.1 - 1.7e-19 70.2 4.7 1.7e-19 70.2 3.3 4.3 3 2 1 4 4 4 2 Stm1 SAGA-Tad1 PF12767.2 AAS54340.1 - 0.68 9.5 7.2 0.86 9.2 4.7 1.3 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit NUDIX PF00293.23 AAS54341.1 - 3.1e-16 59.2 0.0 8.8e-16 57.7 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain Mem_trans PF03547.13 AAS54342.1 - 1.1e-47 162.1 0.0 2.3e-47 161.1 0.0 1.5 1 1 0 1 1 1 1 Membrane transport protein Cyd_oper_YbgE PF09600.5 AAS54342.1 - 0.0037 17.3 0.5 0.0037 17.3 0.4 2.6 2 1 0 2 2 2 1 Cyd operon protein YbgE (Cyd_oper_YbgE) AMP-binding PF00501.23 AAS54343.1 - 1.1e-90 304.0 0.5 1.9e-90 303.2 0.1 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 AAS54343.1 - 3.8e-20 72.6 0.2 1.1e-19 71.1 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sec7 PF01369.15 AAS54344.2 - 7.7e-64 214.8 0.0 2.7e-63 213.0 0.0 2.0 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 AAS54344.2 - 6.8e-54 181.8 2.3 6.8e-54 181.8 1.6 3.5 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 AAS54344.2 - 2.2e-28 97.5 3.3 7.5e-28 95.8 0.6 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) GTP_CH_N PF12471.3 AAS54345.1 - 1.8e-80 269.1 0.0 2.5e-80 268.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 AAS54345.1 - 2.3e-19 69.2 0.0 4.1e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF2382 PF09557.5 AAS54345.1 - 0.078 12.8 0.3 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2382) GTP_EFTU PF00009.22 AAS54346.2 - 8.7e-47 158.9 0.0 1.7e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AAS54346.2 - 3e-24 85.0 0.6 8e-24 83.6 0.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AAS54346.2 - 1.6e-07 31.3 0.5 3.8e-07 30.1 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AAS54346.2 - 0.00013 21.9 0.0 0.00041 20.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 AAS54346.2 - 0.21 10.2 1.5 0.34 9.5 1.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit IPK PF03770.11 AAS54347.2 - 4.7e-56 189.5 0.0 5.9e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Zip PF02535.17 AAS54348.2 - 1.2e-55 188.8 10.7 1.6e-55 188.3 7.4 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter ABC2_membrane PF01061.19 AAS54349.2 - 9.3e-83 276.5 48.2 3.9e-46 156.8 15.0 3.0 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 AAS54349.2 - 1.9e-33 114.2 7.0 2.8e-31 107.2 0.4 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 AAS54349.2 - 2.2e-33 115.4 0.0 4.9e-17 62.5 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 AAS54349.2 - 1.1e-21 76.7 0.0 2.6e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 AAS54349.2 - 5.1e-06 26.0 0.0 0.00035 20.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AAS54349.2 - 8.8e-06 24.9 0.0 0.0015 17.7 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 AAS54349.2 - 0.0002 21.3 0.3 0.021 14.8 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 AAS54349.2 - 0.00075 18.9 0.4 0.033 13.7 0.1 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain cobW PF02492.14 AAS54349.2 - 0.00095 18.6 0.9 0.0083 15.5 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 AAS54349.2 - 0.0017 18.6 0.1 0.022 15.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 AAS54349.2 - 0.0037 16.5 0.0 0.1 11.8 0.0 2.7 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AAS54349.2 - 0.0051 17.1 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AAS54349.2 - 0.0055 16.5 0.1 0.086 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AAS54349.2 - 0.0069 16.5 0.1 0.91 9.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 AAS54349.2 - 0.0078 16.1 1.7 1.4 8.8 0.0 3.1 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 AAS54349.2 - 0.014 15.1 1.1 4.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 AAS54349.2 - 0.031 15.0 0.0 0.68 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.2 AAS54349.2 - 0.036 13.1 50.4 0.006 15.6 10.8 3.4 2 2 1 3 3 3 0 ABC-2 family transporter protein MMR_HSR1 PF01926.18 AAS54349.2 - 0.042 13.8 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 AAS54349.2 - 0.13 11.8 0.5 2.7 7.6 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.1 AAS54349.2 - 0.16 11.5 3.6 4.1 6.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain HMG_box PF00505.14 AAS54350.1 - 2.7e-12 46.7 3.3 2.7e-12 46.7 2.3 2.2 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AAS54350.1 - 9.8e-09 35.4 2.6 9.8e-09 35.4 1.8 2.2 2 0 0 2 2 2 1 HMG-box domain MRP-S28 PF10213.4 AAS54351.1 - 3.7e-51 172.4 0.9 6.3e-51 171.7 0.6 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF4158 PF13700.1 AAS54351.1 - 0.015 14.8 1.6 0.47 9.9 0.1 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4158) Ada3 PF10198.4 AAS54352.1 - 6.8e-47 158.5 2.7 1.6e-46 157.2 1.9 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Peptidase_M16 PF00675.15 AAS54353.1 - 1e-50 171.3 0.0 1.8e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AAS54353.1 - 5.9e-35 120.6 0.0 2.5e-34 118.5 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain CybS PF05328.7 AAS54354.1 - 1.2e-50 170.5 0.0 1.5e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 CybS YjgP_YjgQ PF03739.9 AAS54354.1 - 0.039 12.7 0.1 0.047 12.4 0.1 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family EI24 PF07264.6 AAS54354.1 - 0.11 11.9 0.6 0.14 11.5 0.4 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) PAP_RNA-bind PF04926.10 AAS54355.1 - 0.13 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain PXA PF02194.10 AAS54356.1 - 0.00012 21.6 0.7 0.00061 19.4 0.5 2.2 1 1 0 1 1 1 1 PXA domain PseudoU_synth_2 PF00849.17 AAS54357.1 - 1.3e-17 64.1 0.0 2.7e-16 59.8 0.0 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase Nipped-B_C PF12830.2 AAS54358.1 - 5.6e-44 150.0 8.2 1.2e-43 148.9 2.8 3.3 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 AAS54358.1 - 3.7e-15 55.5 0.9 5.8e-14 51.6 0.1 3.4 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Spo0A_C PF08769.6 AAS54358.1 - 0.03 14.1 0.0 0.16 11.8 0.0 2.2 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Soyouz_module PF14313.1 AAS54358.1 - 0.2 11.2 0.4 11 5.7 0.0 2.8 3 0 0 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) SAS4 PF15460.1 AAS54359.2 - 1.3e-28 98.7 4.1 4.2e-28 97.1 2.8 1.8 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Amino_oxidase PF01593.19 AAS54359.2 - 0.11 11.5 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Metallophos PF00149.23 AAS54360.2 - 5.2e-12 45.5 0.8 1.1e-11 44.5 0.5 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sec10 PF07393.6 AAS54361.2 - 4e-206 686.4 24.5 4.9e-206 686.1 17.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 AvrRpt-cleavage PF05627.6 AAS54361.2 - 0.2 10.7 0.1 0.4 9.7 0.1 1.5 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr Phosducin PF02114.11 AAS54362.1 - 1.3e-09 37.1 0.0 1.6e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 AAS54362.1 - 3.7e-06 26.5 0.0 5.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Cas_Csd1 PF09709.5 AAS54362.1 - 0.042 12.1 0.1 0.049 11.9 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) Acetyltransf_6 PF13480.1 AAS54362.1 - 0.16 11.9 1.4 0.3 11.0 0.9 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ubiquitin PF00240.18 AAS54363.1 - 2.9e-35 119.4 0.6 1.3e-34 117.4 0.5 1.9 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 AAS54363.1 - 3.1e-23 81.3 0.9 5.6e-23 80.4 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 AAS54363.1 - 6.5e-20 70.5 0.7 1.4e-19 69.5 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AAS54363.1 - 1.2e-05 25.4 0.1 4.5e-05 23.6 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 AAS54363.1 - 0.0002 21.1 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 AAS54363.1 - 0.00092 19.0 0.4 0.0023 17.7 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 AAS54363.1 - 0.0034 17.2 0.3 0.005 16.6 0.2 1.3 1 0 0 1 1 1 1 IBR domain DUF2407 PF10302.4 AAS54363.1 - 0.0056 16.8 0.4 0.0075 16.4 0.3 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 AAS54363.1 - 0.07 13.1 0.1 0.18 11.8 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) DUF2207 PF09972.4 AAS54363.1 - 0.095 11.2 0.3 0.099 11.2 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Nudix_N_2 PF14803.1 AAS54363.1 - 0.19 11.4 2.6 0.53 10.0 1.7 1.8 1 1 0 1 1 1 0 Nudix N-terminal Plexin_cytopl PF08337.7 AAS54363.1 - 0.28 9.4 1.3 8.3 4.5 0.0 2.0 1 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain HALZ PF02183.13 AAS54364.2 - 0.51 10.0 3.7 1.6 8.4 2.6 2.0 1 1 0 1 1 1 0 Homeobox associated leucine zipper PRELI PF04707.9 AAS54365.1 - 8.2e-52 174.9 0.3 1.2e-51 174.4 0.2 1.2 1 0 0 1 1 1 1 PRELI-like family zf-DHHC PF01529.15 AAS54366.1 - 1.9e-36 125.1 5.1 1.9e-36 125.1 3.5 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase AzlD PF05437.7 AAS54366.1 - 0.019 14.8 1.5 0.019 14.8 1.0 1.9 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) ABC2_membrane_5 PF13346.1 AAS54366.1 - 0.043 13.0 10.9 0.59 9.3 1.0 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4271 PF14093.1 AAS54366.1 - 1.2 8.8 11.0 0.4 10.3 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) dCMP_cyt_deam_1 PF00383.17 AAS54368.1 - 4.2e-16 58.4 0.6 5.3e-16 58.1 0.4 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 AAS54368.1 - 2.5e-09 37.1 2.3 2.7e-08 33.8 0.3 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 AAS54368.1 - 0.0065 15.8 1.6 0.9 8.8 0.1 2.1 1 1 0 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases BMC PF00936.14 AAS54368.1 - 0.093 12.4 0.1 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 BMC domain Peptidase_M24 PF00557.19 AAS54369.1 - 1.3e-46 158.8 0.0 1.5e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Cpn60_TCP1 PF00118.19 AAS54370.1 - 2e-144 481.8 1.8 2.2e-144 481.6 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sec1 PF00995.18 AAS54371.1 - 1.6e-145 485.9 2.1 1.9e-145 485.7 1.5 1.0 1 0 0 1 1 1 1 Sec1 family TIP49 PF06068.8 AAS54372.1 - 7.9e-186 617.5 0.9 9.2e-186 617.3 0.6 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 AAS54372.1 - 9.2e-09 35.5 1.0 3.4e-05 24.0 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AAS54372.1 - 1e-06 27.9 3.8 0.00023 20.2 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AAS54372.1 - 0.00019 21.4 0.3 0.17 11.8 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.1 AAS54372.1 - 0.00092 19.2 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AAS54372.1 - 0.0045 16.7 0.1 0.019 14.7 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain DnaB_C PF03796.10 AAS54372.1 - 0.0051 15.7 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Zeta_toxin PF06414.7 AAS54372.1 - 0.013 14.6 0.2 0.031 13.3 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin CPT PF07931.7 AAS54372.1 - 0.023 14.3 0.0 0.053 13.1 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.16 AAS54372.1 - 0.077 12.1 0.2 4.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 AAS54372.1 - 0.11 11.4 0.1 0.68 8.7 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 SIR2 PF02146.12 AAS54373.1 - 1.3e-30 106.4 0.0 2e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Zn_Tnp_IS1595 PF12760.2 AAS54373.1 - 0.4 10.5 4.6 9.3 6.1 0.0 3.1 3 0 0 3 3 3 0 Transposase zinc-ribbon domain DUF3039 PF11238.3 AAS54373.1 - 0.43 10.0 5.4 1.7 8.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3039) ATP_bind_1 PF03029.12 AAS54374.1 - 5.6e-85 284.6 0.0 6.3e-85 284.4 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 AAS54374.1 - 0.00028 20.4 0.0 0.00047 19.6 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 AAS54374.1 - 0.00046 21.0 0.3 0.0012 19.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 AAS54374.1 - 0.0019 17.0 0.0 0.0046 15.7 0.0 1.5 2 0 0 2 2 2 1 ArgK protein MMR_HSR1 PF01926.18 AAS54374.1 - 0.0024 17.8 0.0 0.0051 16.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.18 AAS54374.1 - 0.0032 16.8 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 AAS54374.1 - 0.0079 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 AAS54374.1 - 0.008 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 AAS54374.1 - 0.0082 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain KAP_NTPase PF07693.9 AAS54374.1 - 0.0093 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain GTP_EFTU PF00009.22 AAS54374.1 - 0.011 15.2 0.0 0.99 8.8 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_30 PF13604.1 AAS54374.1 - 0.014 14.9 0.0 0.068 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AAS54374.1 - 0.033 14.3 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 AAS54374.1 - 0.035 13.7 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 AAS54374.1 - 0.048 12.5 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 AAS54374.1 - 0.057 13.3 0.2 0.68 9.8 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_33 PF13671.1 AAS54374.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AAS54374.1 - 0.064 13.4 0.0 0.17 12.0 0.0 1.8 2 1 0 2 2 1 0 AAA domain DUF87 PF01935.12 AAS54374.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 ABC_tran PF00005.22 AAS54374.1 - 0.069 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter cobW PF02492.14 AAS54374.1 - 0.083 12.3 0.0 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 AAS54374.1 - 0.14 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain zf-CCCH PF00642.19 AAS54375.2 - 6.9e-06 25.6 4.2 1.3e-05 24.6 2.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.1 AAS54375.2 - 4.2 7.6 146.8 0.025 14.7 30.5 5.1 1 1 3 4 4 4 0 Nucleoporin FG repeat region Arv1 PF04161.8 AAS54376.1 - 7.6e-80 267.6 4.2 1.1e-79 267.1 2.9 1.2 1 0 0 1 1 1 1 Arv1-like family DUF221 PF02714.10 AAS54377.1 - 1.1e-99 333.3 20.3 1.1e-99 333.3 14.0 1.8 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AAS54377.1 - 4e-38 130.4 1.2 4e-38 130.4 0.8 2.6 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 AAS54377.1 - 1.3e-12 48.0 0.1 3.4e-12 46.7 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) PI3Ka PF00613.15 AAS54378.1 - 2.2e-64 216.0 1.1 2.2e-64 216.0 0.8 1.6 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 AAS54378.1 - 3.7e-45 154.2 0.0 4.9e-44 150.5 0.0 2.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 AAS54378.1 - 3.3e-24 85.2 0.1 1.5e-23 83.1 0.0 2.2 3 0 0 3 3 3 1 Phosphoinositide 3-kinase C2 DEAD PF00270.24 AAS54379.1 - 1.3e-39 135.3 0.1 5.1e-39 133.4 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS54379.1 - 1.1e-23 82.8 0.3 8.5e-23 80.0 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AAS54379.1 - 3.6e-07 30.2 0.0 8.4e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Terminase_1 PF03354.10 AAS54379.1 - 0.0013 17.2 0.0 0.0023 16.4 0.0 1.3 1 0 0 1 1 1 1 Phage Terminase 6PF2K PF01591.13 AAS54379.1 - 0.019 14.0 0.4 0.039 13.0 0.3 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase SNF2_N PF00176.18 AAS54379.1 - 0.027 13.2 0.0 0.046 12.5 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain PFK PF00365.15 AAS54379.1 - 0.11 11.4 0.0 0.25 10.2 0.0 1.6 1 0 0 1 1 1 0 Phosphofructokinase GAS PF13851.1 AAS54380.1 - 0.01 15.0 5.1 0.02 14.0 3.5 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3665 PF12427.3 AAS54380.1 - 0.021 14.1 0.1 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Retrotrans_gag PF03732.12 AAS54380.1 - 0.038 14.0 1.6 6.9 6.8 0.0 2.8 3 1 0 3 3 3 0 Retrotransposon gag protein DUF1759 PF03564.10 AAS54380.1 - 0.089 12.5 2.7 6.5 6.5 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) CoaE PF01121.15 AAS54381.1 - 2.1e-60 203.1 0.1 3.5e-60 202.4 0.1 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 AAS54381.1 - 5e-09 37.0 0.0 1.2e-08 35.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AAS54381.1 - 2.2e-05 24.3 4.7 3.1e-05 23.8 0.6 2.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AAS54381.1 - 9.6e-05 22.6 2.4 0.0005 20.3 0.1 3.0 2 1 0 2 2 2 1 AAA domain PRK PF00485.13 AAS54381.1 - 0.00094 18.7 0.1 0.012 15.1 0.0 2.4 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Cytidylate_kin2 PF13189.1 AAS54381.1 - 0.0018 18.2 3.0 0.011 15.6 0.0 2.4 3 0 0 3 3 3 1 Cytidylate kinase-like family AAA_28 PF13521.1 AAS54381.1 - 0.0024 17.8 0.1 0.0062 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 AAS54381.1 - 0.0028 17.5 0.2 0.021 14.6 0.0 2.4 3 1 0 3 3 3 1 Shikimate kinase DUF2262 PF10020.4 AAS54381.1 - 0.021 15.0 0.4 1.9 8.7 0.0 2.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2262) tRNA_lig_kinase PF08303.6 AAS54381.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 tRNA ligase kinase domain ApbA_C PF08546.6 AAS54382.1 - 1.2e-17 64.0 0.0 1.8e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal SET PF00856.23 AAS54383.1 - 0.0035 17.6 0.6 0.011 16.0 0.4 1.8 1 1 0 1 1 1 1 SET domain BPL_LplA_LipB PF03099.14 AAS54384.1 - 2.5e-15 56.5 0.0 4.1e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family FHA PF00498.21 AAS54385.3 - 2.7e-17 62.6 3.1 7.3e-17 61.2 0.2 2.8 2 1 1 3 3 3 1 FHA domain Band_7_1 PF13421.1 AAS54385.3 - 0.067 12.6 2.0 0.12 11.8 1.4 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family CCDC84 PF14968.1 AAS54385.3 - 0.083 12.3 4.1 0.12 11.8 2.8 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 ISG65-75 PF11727.3 AAS54385.3 - 0.14 11.2 8.4 0.21 10.6 5.8 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF4407 PF14362.1 AAS54385.3 - 0.45 9.4 5.0 0.74 8.7 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.10 AAS54385.3 - 1.1 8.4 16.5 1.6 7.8 11.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Bud13 PF09736.4 AAS54385.3 - 10 6.4 10.3 17 5.6 7.2 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DASH_Spc19 PF08287.6 AAS54386.1 - 5.6e-42 142.9 9.8 7.8e-42 142.4 6.8 1.2 1 0 0 1 1 1 1 Spc19 DUF4515 PF14988.1 AAS54386.1 - 0.0012 18.5 2.3 0.0014 18.3 0.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4515) Sds3 PF08598.6 AAS54386.1 - 0.01 15.3 1.4 0.013 15.0 1.0 1.3 1 0 0 1 1 1 0 Sds3-like Taxilin PF09728.4 AAS54386.1 - 0.014 14.4 3.4 0.02 13.9 2.4 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF3209 PF11483.3 AAS54386.1 - 0.045 14.0 0.7 0.12 12.6 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3209) BLOC1_2 PF10046.4 AAS54386.1 - 0.13 12.4 1.4 2 8.6 0.4 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2951 PF11166.3 AAS54386.1 - 0.36 10.7 3.9 0.13 12.1 0.4 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2951) SYCE1 PF15233.1 AAS54386.1 - 0.73 9.7 7.7 0.29 11.0 1.8 2.2 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 Exonuc_VII_S PF02609.11 AAS54386.1 - 1.2 9.0 5.4 2.1 8.1 0.4 2.8 2 1 1 3 3 3 0 Exonuclease VII small subunit TBCA PF02970.11 AAS54386.1 - 1.6 8.8 6.8 0.33 11.0 1.8 2.1 2 1 0 2 2 2 0 Tubulin binding cofactor A DUF848 PF05852.6 AAS54386.1 - 1.9 8.2 6.4 0.39 10.5 2.3 1.5 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Prefoldin_2 PF01920.15 AAS54386.1 - 3.8 7.3 7.7 0.9 9.3 0.8 2.6 3 0 0 3 3 3 0 Prefoldin subunit IncA PF04156.9 AAS54386.1 - 5.6 6.5 14.4 1.7e+02 1.6 10.0 2.6 1 1 0 1 1 1 0 IncA protein DUF2508 PF10704.4 AAS54386.1 - 7.9 6.7 7.0 6.1 7.0 0.4 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2508) Rogdi_lz PF10259.4 AAS54387.1 - 1.1e-83 280.5 1.0 1.2e-83 280.3 0.7 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Coq4 PF05019.8 AAS54388.1 - 1.4e-96 321.7 0.0 1.7e-96 321.4 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 MscS_porin PF12795.2 AAS54388.1 - 0.0068 15.7 0.3 0.011 15.0 0.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain GvpK PF05121.7 AAS54388.1 - 0.14 11.9 2.3 0.26 11.1 0.1 2.4 3 0 0 3 3 3 0 Gas vesicle protein K DUF1087 PF06465.8 AAS54388.1 - 0.39 10.6 0.1 0.39 10.6 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) Cation_efflux PF01545.16 AAS54389.1 - 6.9e-49 166.4 13.6 6.9e-49 166.4 9.4 3.2 3 1 0 3 3 3 1 Cation efflux family AF-4 PF05110.8 AAS54389.1 - 0.079 10.8 3.8 0.11 10.3 2.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Topoisom_bac PF01131.15 AAS54390.1 - 3.8e-97 325.6 0.0 4.5e-97 325.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 AAS54390.1 - 5.2e-17 61.6 0.0 1.1e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Toprim domain EST1_DNA_bind PF10373.4 AAS54391.1 - 2.3e-52 177.9 0.4 3.9e-52 177.1 0.3 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 AAS54391.1 - 5e-30 104.1 0.1 1.1e-28 99.8 0.0 2.8 2 1 1 3 3 3 1 Telomerase activating protein Est1 Zn_clus PF00172.13 AAS54392.1 - 4.9e-11 42.3 7.1 8.1e-11 41.6 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.14 AAS54393.2 - 7.6e-16 57.8 0.0 1.1e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V E1-E2_ATPase PF00122.15 AAS54394.2 - 1e-62 211.2 7.6 1e-62 211.2 5.3 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AAS54394.2 - 5.5e-34 117.2 6.0 5.5e-34 117.2 4.1 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AAS54394.2 - 5.7e-30 105.3 0.1 1.8e-25 90.5 0.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AAS54394.2 - 2.4e-18 65.8 0.0 5e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 AAS54394.2 - 2.4e-16 58.9 0.0 6.2e-16 57.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 AAS54394.2 - 2.6e-15 57.0 0.0 6e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AAS54394.2 - 0.006 16.1 0.9 0.006 16.1 0.6 2.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PIP5K PF01504.13 AAS54395.1 - 4.4e-86 288.0 1.6 6.8e-86 287.4 1.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase W2 PF02020.13 AAS54396.1 - 1.5e-15 56.8 0.4 1.5e-15 56.8 0.3 2.7 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 AAS54396.1 - 4.5e-13 48.0 14.6 0.0024 17.2 0.7 4.4 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 AAS54396.1 - 3.7e-11 42.8 0.0 7.8e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 AAS54396.1 - 0.0021 17.6 17.7 16 5.1 0.3 3.7 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 AAS54396.1 - 0.0048 16.9 0.2 0.019 15.0 0.0 2.0 2 0 0 2 2 2 1 MobA-like NTP transferase domain Fucokinase PF07959.7 AAS54396.1 - 0.033 12.7 0.0 0.069 11.7 0.0 1.5 1 0 0 1 1 1 0 L-fucokinase Ras PF00071.17 AAS54397.1 - 3e-51 173.0 0.0 3.6e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS54397.1 - 9.7e-14 51.8 0.0 1.3e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS54397.1 - 1.3e-07 31.0 0.0 1.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Cpn60_TCP1 PF00118.19 AAS54398.2 - 4.1e-142 474.2 10.0 4.7e-142 474.0 6.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fungal_trans_2 PF11951.3 AAS54399.1 - 1.7e-09 36.7 0.4 1.7e-09 36.7 0.3 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS54399.1 - 1.2e-08 34.7 13.1 2.1e-08 33.9 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aha1_N PF09229.6 AAS54400.1 - 4.3e-37 126.9 0.0 1.2e-36 125.5 0.0 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 AAS54400.1 - 2.5e-13 50.1 0.2 4.6e-13 49.3 0.2 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 AAS54400.1 - 6.6e-06 26.3 0.2 1.7e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Med3 PF11593.3 AAS54400.1 - 0.46 9.6 2.9 0.63 9.2 2.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Proteasome PF00227.21 AAS54401.1 - 1e-46 158.6 0.0 1.5e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AAS54401.1 - 1.7e-15 55.9 0.1 3.3e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Protoglobin PF11563.3 AAS54401.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protoglobin Rsc14 PF08586.5 AAS54402.1 - 1.8e-42 143.8 0.2 2.5e-42 143.4 0.1 1.2 1 0 0 1 1 1 1 RSC complex, Rsc14/Ldb7 subunit ERG4_ERG24 PF01222.12 AAS54403.1 - 6.5e-166 552.1 16.0 7.4e-166 551.9 11.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PUF PF00806.14 AAS54404.2 - 2.8e-64 209.1 5.5 1.5e-09 36.8 0.2 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Toxin_17 PF08086.6 AAS54404.2 - 1.3 9.1 5.5 1.2 9.2 2.6 1.9 1 1 0 1 1 1 0 Ergtoxin family E1-E2_ATPase PF00122.15 AAS54405.1 - 5.8e-62 208.7 8.6 1.1e-61 207.8 6.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AAS54405.1 - 7.7e-24 85.3 0.0 1.4e-23 84.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AAS54405.1 - 1.4e-14 54.7 0.0 3e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AAS54405.1 - 4.3e-11 42.1 0.3 2.6e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AAS54405.1 - 0.00093 18.8 0.7 0.0026 17.3 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AAS54405.1 - 0.021 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF2614 PF11023.3 AAS54405.1 - 4.7 7.0 9.9 0.13 12.0 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) Zn_clus PF00172.13 AAS54407.1 - 2.7e-07 30.3 12.9 6.2e-07 29.2 9.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UDPGP PF01704.13 AAS54408.1 - 2.1e-189 629.3 0.0 2.8e-189 628.9 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 AAS54408.1 - 0.0061 15.1 0.1 0.031 12.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4301) HAD_2 PF13419.1 AAS54409.1 - 2e-14 54.2 0.0 2.3e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 AAS54409.1 - 0.00013 21.8 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AAS54409.1 - 0.00095 19.6 0.0 0.0011 19.3 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AAS54409.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Pribosyl_synth PF14572.1 AAS54410.1 - 1.3e-39 135.8 2.6 3.8e-35 121.2 1.5 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 AAS54410.1 - 1.5e-38 131.1 0.1 6e-38 129.1 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 AAS54410.1 - 3.3e-12 46.2 0.5 8.1e-12 44.9 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AAS54410.1 - 0.00073 18.8 0.1 0.0014 17.8 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF218 PF02698.12 AAS54410.1 - 0.14 11.6 0.1 0.53 9.7 0.0 1.9 2 0 0 2 2 2 0 DUF218 domain zf-UBP PF02148.14 AAS54411.1 - 9.4e-22 76.9 8.3 2.8e-21 75.3 5.8 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.7 AAS54411.1 - 1.5e-19 69.5 0.0 3.2e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.1 AAS54411.1 - 8.5e-10 38.3 9.9 8.5e-10 38.3 6.9 2.8 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.1 AAS54411.1 - 2.6e-06 27.0 7.8 2.6e-06 27.0 5.4 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 AAS54411.1 - 2.3e-05 23.9 20.6 0.00017 21.1 4.4 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS54411.1 - 5.6e-05 23.0 8.5 5.6e-05 23.0 5.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AAS54411.1 - 0.00029 20.6 4.1 0.00029 20.6 2.9 2.2 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 AAS54411.1 - 0.00034 20.2 8.4 0.00034 20.2 5.9 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AAS54411.1 - 0.001 19.1 7.5 0.001 19.1 5.2 2.4 1 1 1 2 2 2 1 RING-H2 zinc finger Macoilin PF09726.4 AAS54411.1 - 0.0016 16.8 3.6 0.0022 16.3 2.5 1.1 1 0 0 1 1 1 1 Transmembrane protein zf-RING_UBOX PF13445.1 AAS54411.1 - 0.0019 17.8 4.1 0.0019 17.8 2.9 3.2 2 1 0 2 2 2 1 RING-type zinc-finger Rootletin PF15035.1 AAS54411.1 - 0.0063 16.5 9.6 0.012 15.6 6.6 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Filament PF00038.16 AAS54411.1 - 0.0065 15.9 4.6 0.01 15.3 3.2 1.2 1 0 0 1 1 1 1 Intermediate filament protein zf-RING_4 PF14570.1 AAS54411.1 - 0.012 15.1 8.4 0.012 15.1 5.8 1.8 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain Nup54 PF13874.1 AAS54411.1 - 0.018 14.7 1.9 0.034 13.8 1.3 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 PspA_IM30 PF04012.7 AAS54411.1 - 0.043 13.1 7.7 0.12 11.7 5.4 1.5 1 1 0 1 1 1 0 PspA/IM30 family DUF2205 PF10224.4 AAS54411.1 - 0.08 12.5 2.0 0.17 11.4 1.4 1.6 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) XkdW PF09636.5 AAS54411.1 - 0.14 12.0 1.4 0.34 10.7 1.0 1.6 1 0 0 1 1 1 0 XkdW protein DUF972 PF06156.8 AAS54411.1 - 0.21 11.9 5.5 0.072 13.4 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PolC_DP2 PF03833.8 AAS54411.1 - 0.59 7.7 2.8 0.87 7.1 1.9 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 CENP-F_leu_zip PF10473.4 AAS54411.1 - 1.4 8.7 13.3 0.61 9.9 6.8 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 AAS54411.1 - 2.8 7.7 7.1 0.2 11.4 0.7 2.3 3 0 0 3 3 2 0 Homeobox associated leucine zipper IncA PF04156.9 AAS54411.1 - 4.9 6.7 12.9 22 4.5 8.7 2.0 1 1 0 1 1 1 0 IncA protein FANCI_S3 PF14677.1 AAS54412.1 - 0.0028 17.0 0.1 0.01 15.2 0.1 1.9 1 0 0 1 1 1 1 FANCI solenoid 3 HEAT_2 PF13646.1 AAS54412.1 - 0.067 13.4 1.0 5.6 7.3 0.0 4.2 5 1 0 5 5 5 0 HEAT repeats Form_Nir_trans PF01226.12 AAS54413.2 - 1.3e-64 217.5 25.3 1.6e-64 217.2 17.6 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter HEAT_2 PF13646.1 AAS54414.1 - 0.00011 22.3 0.0 0.049 13.9 0.0 3.8 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 AAS54414.1 - 0.0015 18.4 1.5 3.1 8.1 0.0 5.7 5 1 1 6 6 6 1 HEAT repeat DIL PF01843.14 AAS54414.1 - 0.018 14.8 2.3 0.19 11.6 0.2 2.8 2 0 0 2 2 2 0 DIL domain Herpes_UL51 PF04540.8 AAS54414.1 - 0.02 14.4 0.3 0.85 9.1 0.1 2.5 2 0 0 2 2 2 0 Herpesvirus UL51 protein PixA PF12306.3 AAS54414.1 - 0.032 14.0 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Inclusion body protein Exonuc_VII_S PF02609.11 AAS54414.1 - 0.051 13.3 2.9 0.062 13.0 0.1 2.4 2 0 0 2 2 2 0 Exonuclease VII small subunit PHD PF00628.24 AAS54415.1 - 6e-16 57.8 21.4 1.2e-10 40.8 6.2 3.1 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.1 AAS54415.1 - 0.0018 17.5 11.5 0.095 12.0 0.2 3.7 3 0 0 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.1 AAS54415.1 - 0.019 15.0 7.8 0.04 14.0 1.3 2.6 2 0 0 2 2 2 0 PHD-like zinc-binding domain Flu_NS2 PF00601.14 AAS54415.1 - 0.061 13.5 0.1 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) zf-PHD-like PF15446.1 AAS54415.1 - 1.3 8.2 13.0 0.44 9.8 0.3 3.0 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 AAS54415.1 - 1.5 8.5 10.6 0.46 10.2 0.1 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 AAS54415.1 - 3.9 7.2 16.8 0.68 9.7 1.7 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) dsDNA_bind PF01984.15 AAS54416.2 - 2.2e-21 75.8 6.8 1.1e-20 73.5 4.7 1.7 1 1 0 1 1 1 1 Double-stranded DNA-binding domain EF-1_beta_acid PF10587.4 AAS54416.2 - 0.044 13.9 0.7 0.044 13.9 0.5 2.5 4 0 0 4 4 4 0 Eukaryotic elongation factor 1 beta central acidic region Cu_amine_oxid PF01179.15 AAS54417.2 - 4.4e-142 473.6 0.0 5.2e-142 473.3 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 AAS54417.2 - 4.1e-05 23.5 0.0 0.00013 21.9 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cg6151-P PF10233.4 AAS54418.1 - 2.7e-37 127.2 10.1 3.3e-37 126.9 7.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P YhfT PF10797.4 AAS54418.1 - 0.0062 15.4 2.8 0.0078 15.0 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function zf-C2H2 PF00096.21 AAS54419.1 - 1.9e-05 24.7 19.5 0.00031 20.9 4.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS54419.1 - 0.00021 21.3 17.5 0.0023 18.1 3.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 AAS54419.1 - 0.0011 19.0 5.4 0.0019 18.3 3.8 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding CC2D2AN-C2 PF15625.1 AAS54419.1 - 0.017 14.5 0.1 0.034 13.6 0.1 1.4 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain GAGA PF09237.6 AAS54419.1 - 0.11 12.0 2.1 0.27 10.8 1.1 1.9 1 1 1 2 2 2 0 GAGA factor DUF2024 PF09630.5 AAS54419.1 - 0.29 10.8 2.0 0.4 10.4 0.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2024) zf-C2H2_2 PF12756.2 AAS54419.1 - 0.41 10.7 9.2 4.6 7.4 2.1 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 AAS54419.1 - 0.66 10.3 19.0 1 9.7 1.1 3.3 3 0 0 3 3 3 0 Zinc-finger double domain NIF PF03031.13 AAS54420.1 - 1e-51 174.7 0.0 1.3e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MFS_1 PF07690.11 AAS54421.1 - 5.8e-40 137.0 18.8 7.1e-40 136.7 12.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AAS54421.1 - 2.1e-11 43.0 10.1 2.1e-11 43.0 7.0 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter Malic_M PF03949.10 AAS54422.2 - 2.8e-75 253.1 0.0 3.8e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 AAS54422.2 - 8.7e-61 204.6 0.0 1.3e-60 204.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain TFIIE_alpha PF02002.12 AAS54423.2 - 7.9e-30 102.4 0.1 2.8e-29 100.6 0.1 2.0 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 AAS54423.2 - 2.9e-08 32.9 0.1 6.7e-08 31.7 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding GntR PF00392.16 AAS54423.2 - 0.052 12.9 0.0 0.17 11.3 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family zf-CHY PF05495.7 AAS54423.2 - 0.11 12.6 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 CHY zinc finger DUF4337 PF14235.1 AAS54423.2 - 3.5 7.4 7.1 0.6 9.9 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) ThiF PF00899.16 AAS54424.2 - 1.6e-37 128.3 0.0 3.1e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 AAS54424.2 - 0.00096 19.2 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 AAS54424.2 - 0.0042 17.0 0.1 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.11 AAS54424.2 - 0.055 12.9 0.1 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 AAS54424.2 - 0.13 11.2 0.1 0.31 9.9 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase Mito_carr PF00153.22 AAS54425.1 - 6.5e-61 202.0 0.1 5e-20 71.0 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 AAS54426.1 - 1.8e-60 200.6 2.5 1.5e-22 79.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2370 PF10176.4 AAS54427.2 - 7.3e-82 274.2 0.0 8.6e-82 273.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) CAAD PF14159.1 AAS54427.2 - 0.13 11.8 0.0 0.71 9.5 0.0 2.0 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase SNF5 PF04855.7 AAS54428.2 - 7.3e-65 218.8 1.8 7.3e-65 218.8 1.2 6.2 2 2 1 3 3 3 1 SNF5 / SMARCB1 / INI1 Adap_comp_sub PF00928.16 AAS54429.2 - 2.4e-36 125.2 0.0 2.9e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AAS54429.2 - 0.021 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Clathrin adaptor complex small chain AP4E_app_platf PF14807.1 AAS54429.2 - 0.035 14.3 0.1 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform DUF3663 PF12404.3 AAS54429.2 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase adh_short PF00106.20 AAS54430.1 - 2.1e-66 222.9 12.0 7.3e-34 117.0 0.7 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 AAS54430.1 - 9.5e-32 110.1 6.3 5.1e-16 58.8 0.1 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 AAS54430.1 - 5.8e-26 90.2 0.0 1.2e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain adh_short_C2 PF13561.1 AAS54430.1 - 4.6e-22 78.9 1.2 8.1e-12 45.4 0.3 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 AAS54430.1 - 0.00016 21.4 0.0 0.00043 20.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase DUF1776 PF08643.5 AAS54430.1 - 0.1 11.7 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF4161 PF13722.1 AAS54430.1 - 0.22 11.7 0.7 16 5.7 0.1 2.7 3 0 0 3 3 3 0 C-terminal domain on CstA (DUF4161) 3HCDH_N PF02737.13 AAS54430.1 - 6.9 6.2 7.9 13 5.3 0.6 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain QCR10 PF09796.4 AAS54431.2 - 2.4e-28 97.5 0.3 3.1e-28 97.2 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 AAS54431.2 - 0.03 14.0 0.4 0.04 13.6 0.2 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Tricorn_C1 PF14684.1 AAS54431.2 - 0.12 12.2 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Tricorn protease C1 domain ICL PF00463.16 AAS54433.2 - 5.4e-173 575.9 0.0 6.3e-173 575.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 AAS54433.2 - 1.6e-09 37.3 0.1 4e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Daxx PF03344.10 AAS54434.2 - 0.00074 18.1 24.4 0.00099 17.7 16.9 1.2 1 0 0 1 1 1 1 Daxx Family TFIIA PF03153.8 AAS54434.2 - 0.0014 18.5 19.4 0.0018 18.2 13.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 AAS54434.2 - 0.0035 15.3 28.2 0.0046 14.9 19.5 1.1 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.5 AAS54434.2 - 0.061 12.3 18.9 0.086 11.9 13.1 1.2 1 0 0 1 1 1 0 BUD22 Tim54 PF11711.3 AAS54434.2 - 0.51 8.8 5.8 0.74 8.3 4.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop25 PF09805.4 AAS54434.2 - 0.72 9.9 16.0 1.2 9.1 11.1 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CobT PF06213.7 AAS54434.2 - 0.95 8.5 29.3 1.5 7.8 20.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SAPS PF04499.10 AAS54434.2 - 1.4 7.4 6.3 1.8 7.1 4.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.7 AAS54434.2 - 1.5 8.0 30.7 2.2 7.5 21.3 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 AAS54434.2 - 2.1 6.2 25.4 2.8 5.8 17.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.7 AAS54434.2 - 2.6 6.3 28.8 3.4 5.9 19.9 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF1510 PF07423.6 AAS54434.2 - 3.1 7.0 22.0 4.7 6.5 15.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 AAS54434.2 - 4.6 7.2 12.3 7.4 6.5 8.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SGT1 PF07093.6 AAS54434.2 - 8.5 4.6 17.6 11 4.2 12.2 1.1 1 0 0 1 1 1 0 SGT1 protein DUF2722 PF10846.3 AAS54434.2 - 9.2 5.1 11.4 13 4.6 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) AAA_33 PF13671.1 AAS54435.1 - 5.8e-07 29.4 0.1 0.00032 20.5 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 AAS54435.1 - 4.5e-06 26.7 0.0 1.9e-05 24.7 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 AAS54435.1 - 9.1e-06 26.4 0.0 5.5e-05 23.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 AAS54435.1 - 9.8e-06 25.8 0.0 0.0019 18.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 AAS54435.1 - 3.3e-05 23.0 0.0 6.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 AAS54435.1 - 7e-05 22.9 0.0 0.00061 19.9 0.0 2.3 2 1 1 3 3 3 1 AAA domain NACHT PF05729.7 AAS54435.1 - 0.00011 21.9 0.0 0.0062 16.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain KTI12 PF08433.5 AAS54435.1 - 0.00025 20.3 0.0 0.0004 19.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_5 PF07728.9 AAS54435.1 - 0.00069 19.3 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PRK PF00485.13 AAS54435.1 - 0.0023 17.4 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 AAS54435.1 - 0.0026 17.9 0.0 0.0049 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.17 AAS54435.1 - 0.0056 15.5 0.0 0.012 14.4 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain Abhydrolase_5 PF12695.2 AAS54435.1 - 0.012 15.3 0.1 0.51 10.0 0.0 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF258 PF03193.11 AAS54435.1 - 0.018 14.2 0.0 0.045 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 6PF2K PF01591.13 AAS54435.1 - 0.028 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Mg_chelatase PF01078.16 AAS54435.1 - 0.035 13.2 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 AAS54435.1 - 0.038 13.5 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 AAS54435.1 - 0.051 12.9 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Viral_helicase1 PF01443.13 AAS54435.1 - 0.061 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 AAS54435.1 - 0.062 12.2 0.0 0.062 12.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ArgK PF03308.11 AAS54435.1 - 0.065 12.0 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 ArgK protein MMR_HSR1 PF01926.18 AAS54435.1 - 0.068 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 AAS54435.1 - 0.074 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.15 AAS54435.1 - 0.095 12.3 0.0 0.23 11.1 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase ABC_tran PF00005.22 AAS54435.1 - 0.098 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.12 AAS54435.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 AAS54435.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 AAS54435.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3693 PF12472.3 AAS54435.1 - 0.12 12.0 0.0 0.37 10.4 0.0 1.8 1 0 0 1 1 1 0 Phage related protein cobW PF02492.14 AAS54435.1 - 0.13 11.6 0.0 0.66 9.3 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 AAS54435.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 AAS54435.1 - 0.2 10.3 0.0 0.3 9.7 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit ETF_alpha PF00766.14 AAS54436.1 - 2.2e-35 120.0 0.2 4.3e-35 119.2 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 AAS54436.1 - 8e-34 116.7 0.7 1.4e-33 115.8 0.5 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Transcrip_reg PF01709.15 AAS54437.1 - 1.3e-74 250.2 1.7 1.5e-74 250.0 1.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator ATP-synt_F PF01990.12 AAS54438.1 - 1.3e-30 105.6 0.2 1.5e-30 105.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.8 AAS54438.1 - 0.095 11.9 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 CTV_P13 PF06922.6 AAS54438.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein BRCT PF00533.21 AAS54439.2 - 1.3e-12 47.6 0.0 3.5e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 AAS54439.2 - 4.4e-06 26.7 0.1 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain PTCB-BRCT PF12738.2 AAS54439.2 - 0.00012 21.8 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.3 AAS54439.2 - 0.0021 17.7 1.5 0.0023 17.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) Aminotran_3 PF00202.16 AAS54440.1 - 1.1e-86 290.8 0.0 1.3e-86 290.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pyridox_oxase_2 PF12766.2 AAS54441.2 - 6.8e-30 103.3 0.0 1.4e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Mito_carr PF00153.22 AAS54443.1 - 2.9e-72 238.4 1.7 8.3e-25 86.3 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1478 PF07349.6 AAS54443.1 - 0.16 11.3 0.4 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1478) Gtr1_RagA PF04670.7 AAS54444.1 - 2.4e-68 229.7 0.2 3.2e-68 229.3 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 AAS54444.1 - 0.0023 17.2 0.1 0.0059 15.8 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF2118 PF09891.4 AAS54444.1 - 0.022 14.4 0.2 0.4 10.3 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) TYW3 PF02676.9 AAS54445.1 - 2.8e-67 225.8 0.0 3.4e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 MIF4G PF02854.14 AAS54446.2 - 5.2e-46 156.6 0.5 7.4e-46 156.1 0.3 1.2 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 AAS54446.2 - 7.5e-26 89.8 1.7 3.8e-25 87.5 1.2 2.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 AAA PF00004.24 AAS54447.1 - 2.1e-43 147.7 0.0 3.8e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AAS54447.1 - 5.9e-07 29.3 0.0 5.7e-06 26.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AAS54447.1 - 7.8e-07 29.1 0.0 1.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AAS54447.1 - 4.5e-06 26.8 0.0 0.0003 20.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AAS54447.1 - 2.3e-05 24.4 0.0 7.2e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 AAS54447.1 - 5.1e-05 24.0 0.2 0.00014 22.6 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 AAS54447.1 - 0.00013 21.6 0.1 0.00031 20.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 AAS54447.1 - 0.00014 21.0 0.0 0.00027 20.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 AAS54447.1 - 0.00024 20.5 0.0 0.00044 19.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 AAS54447.1 - 0.00069 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AAS54447.1 - 0.0017 18.2 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 AAS54447.1 - 0.0018 18.2 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AAS54447.1 - 0.003 16.6 0.0 0.0068 15.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin DUF2072 PF09845.4 AAS54447.1 - 0.004 17.0 0.3 0.0092 15.9 0.2 1.6 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) AAA_3 PF07726.6 AAS54447.1 - 0.0051 16.4 0.0 0.015 14.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 AAS54447.1 - 0.0064 16.7 0.9 0.032 14.5 0.0 2.5 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 AAS54447.1 - 0.0091 15.1 0.2 0.025 13.7 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 AAS54447.1 - 0.0098 14.6 0.0 0.022 13.4 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus PhoH PF02562.11 AAS54447.1 - 0.011 15.0 0.0 0.046 12.9 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 AAS54447.1 - 0.026 13.9 0.0 0.15 11.5 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_25 PF13481.1 AAS54447.1 - 0.027 13.8 0.1 0.093 12.1 0.0 1.8 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 AAS54447.1 - 0.03 14.4 0.0 0.077 13.1 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 AAS54447.1 - 0.034 13.7 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AAS54447.1 - 0.075 12.6 0.0 0.35 10.4 0.0 1.9 1 1 1 2 2 2 0 NACHT domain DUF815 PF05673.8 AAS54447.1 - 0.076 11.9 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 AAS54447.1 - 0.087 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Tropomyosin PF00261.15 AAS54447.1 - 0.1 11.6 1.8 0.15 11.1 0.2 1.9 2 0 0 2 2 2 0 Tropomyosin Glyco_tran_28_C PF04101.11 AAS54448.1 - 1.3e-21 76.9 0.0 2.4e-21 76.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 AAS54448.1 - 0.0014 17.8 0.1 0.0019 17.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 E1-E2_ATPase PF00122.15 AAS54449.1 - 4.5e-44 150.2 0.0 1.2e-43 148.7 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 AAS54449.1 - 4.4e-32 112.2 0.0 8.3e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AAS54449.1 - 9e-17 61.8 0.0 1.8e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 AAS54449.1 - 1.6e-08 34.5 5.3 4.1e-05 23.6 0.8 3.5 3 0 0 3 3 3 2 Heavy-metal-associated domain Hydrolase_3 PF08282.7 AAS54449.1 - 0.001 18.7 0.4 0.017 14.6 0.1 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase ELFV_dehydrog PF00208.16 AAS54450.1 - 2.7e-60 203.9 0.0 1.2e-59 201.8 0.0 1.9 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 AAS54450.1 - 4e-22 77.5 0.0 4.1e-15 54.3 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase NPR3 PF03666.8 AAS54451.2 - 1.6e-179 597.2 0.0 2.6e-179 596.4 0.0 1.4 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Orthoreo_P17 PF07272.6 AAS54451.2 - 0.02 14.6 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 Orthoreovirus P17 protein RRM_1 PF00076.17 AAS54452.1 - 1.5e-30 104.6 4.4 2.3e-14 52.7 0.3 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS54452.1 - 6.5e-21 73.9 0.8 3.9e-08 33.0 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS54452.1 - 2.1e-20 72.4 0.2 3.3e-08 33.3 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2457 PF10446.4 AAS54452.1 - 0.00014 20.7 14.6 0.0014 17.4 1.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2457) Nup35_RRM_2 PF14605.1 AAS54452.1 - 0.00073 19.2 0.1 3.5 7.4 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 AAS54452.1 - 0.00082 19.1 0.2 0.92 9.3 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM PF05172.8 AAS54452.1 - 0.0013 18.4 0.0 0.13 11.9 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Myc_N PF01056.13 AAS54452.1 - 0.55 9.3 14.3 0.21 10.6 3.2 2.2 2 0 0 2 2 2 0 Myc amino-terminal region DUF4611 PF15387.1 AAS54452.1 - 0.95 9.6 18.4 2.4 8.3 3.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 AAS54452.1 - 1.5 8.3 22.3 0.88 9.1 4.9 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 AAS54452.1 - 1.9 8.7 31.5 1.8 8.8 9.5 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2890 PF11081.3 AAS54452.1 - 2.1 8.3 11.8 1 9.3 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) PBP1_TM PF14812.1 AAS54452.1 - 2.3 8.6 22.3 1 9.7 5.7 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3245 PF11595.3 AAS54452.1 - 3.3 7.9 13.0 2.9 8.1 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) AF1Q PF15017.1 AAS54452.1 - 3.8 7.4 17.5 7.6 6.5 5.0 2.5 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator LAT PF15234.1 AAS54452.1 - 5 6.5 13.5 2.5 7.5 1.7 2.4 2 0 0 2 2 2 0 Linker for activation of T-cells FAM176 PF14851.1 AAS54452.1 - 5.5 6.6 13.3 5.6 6.6 2.8 2.3 2 0 0 2 2 2 0 FAM176 family Nucleoplasmin PF03066.10 AAS54452.1 - 6.5 6.2 28.2 2.8 7.4 8.8 2.3 2 0 0 2 2 2 0 Nucleoplasmin RNA_pol_3_Rpc31 PF11705.3 AAS54452.1 - 7.7 6.3 23.2 0.95 9.3 5.7 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 ANAPC15 PF15243.1 AAS54452.1 - 9.5 6.3 25.6 2.9 8.0 7.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 AAA_2 PF07724.9 AAS54454.1 - 5.5e-46 156.5 0.1 9e-45 152.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 AAS54454.1 - 5.8e-24 84.7 0.1 1.6e-14 54.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 AAS54454.1 - 7.9e-23 80.1 0.9 3e-22 78.2 0.6 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 AAS54454.1 - 4.8e-17 61.9 0.0 1.3e-09 37.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 AAS54454.1 - 1.1e-12 47.6 5.3 8.2e-09 35.2 0.2 3.5 3 0 0 3 3 3 2 Clp amino terminal domain AAA_16 PF13191.1 AAS54454.1 - 1.7e-11 44.4 8.2 0.0004 20.4 0.0 4.9 4 2 2 6 6 4 2 AAA ATPase domain AAA_22 PF13401.1 AAS54454.1 - 1.8e-11 44.3 0.7 2.8e-05 24.2 0.0 3.6 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 AAS54454.1 - 1.8e-11 43.8 0.1 1.7e-08 34.0 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 AAS54454.1 - 8.7e-07 28.8 0.0 0.021 14.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 AAS54454.1 - 2e-05 23.4 2.3 0.099 11.3 0.0 3.7 4 0 0 4 4 4 2 TIP49 C-terminus Mg_chelatase PF01078.16 AAS54454.1 - 6.7e-05 22.1 0.0 0.54 9.3 0.0 3.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 AAS54454.1 - 0.00019 21.1 2.2 1 9.0 0.1 4.1 3 1 1 4 4 4 1 Archaeal ATPase AAA_3 PF07726.6 AAS54454.1 - 0.0002 20.9 0.0 0.24 10.9 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AAS54454.1 - 0.00022 20.9 0.0 0.57 9.8 0.0 3.0 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.1 AAS54454.1 - 0.00035 20.2 0.0 0.64 9.8 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 AAS54454.1 - 0.00063 19.6 0.2 0.04 13.7 0.0 3.4 3 1 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 AAS54454.1 - 0.00066 18.8 0.1 0.026 13.6 0.0 2.9 4 0 0 4 4 3 1 Zeta toxin AAA_17 PF13207.1 AAS54454.1 - 0.001 19.8 9.5 0.02 15.7 0.0 4.2 3 2 0 3 3 2 1 AAA domain IstB_IS21 PF01695.12 AAS54454.1 - 0.0048 16.3 0.0 1.5 8.1 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 AAS54454.1 - 0.0086 16.3 2.6 0.67 10.2 0.0 3.3 3 0 0 3 3 2 1 AAA domain SRP54 PF00448.17 AAS54454.1 - 0.012 15.0 0.0 0.13 11.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 AAS54454.1 - 0.02 14.4 0.0 1.9 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 AAS54454.1 - 0.021 14.7 0.0 0.088 12.7 0.0 2.0 2 0 0 2 2 1 0 Torsin ResIII PF04851.10 AAS54454.1 - 0.028 14.2 0.0 27 4.5 0.0 3.6 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit MobB PF03205.9 AAS54454.1 - 0.038 13.6 0.0 4.6 6.9 0.0 2.9 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 AAS54454.1 - 0.039 14.1 0.0 16 5.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 AAS54454.1 - 0.042 13.4 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.10 AAS54454.1 - 0.049 13.3 0.0 3.8 7.1 0.0 3.3 3 0 0 3 3 3 0 NTPase PEPCK_ATP PF01293.15 AAS54454.1 - 0.069 11.6 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_21 PF13304.1 AAS54454.1 - 0.09 12.7 0.6 3 7.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.22 AAS54454.1 - 0.16 12.2 2.3 4.8 7.4 0.0 3.3 2 1 0 3 3 3 0 ABC transporter AAA_10 PF12846.2 AAS54454.1 - 0.43 9.9 3.0 2.5 7.4 0.0 3.3 4 1 0 4 4 4 0 AAA-like domain APG6 PF04111.7 AAS54454.1 - 0.62 9.0 9.5 1.3 7.9 6.6 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 AAS54454.1 - 3.4 5.4 5.1 5 4.8 3.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.4 AAS54454.1 - 9.8 6.1 11.2 31 4.4 7.7 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein Sod_Cu PF00080.15 AAS54456.2 - 3.8e-16 59.5 0.0 7.2e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Fe-S_biosyn PF01521.15 AAS54457.1 - 3.7e-18 65.4 0.0 5.7e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.2 AAS54457.1 - 0.023 14.4 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) Peptidase_M24 PF00557.19 AAS54458.1 - 4.1e-40 137.5 0.0 6.2e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 AAS54458.1 - 2.3e-11 44.3 0.1 3.6e-09 37.1 0.0 2.5 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain DUF367 PF04034.8 AAS54458.1 - 0.049 13.2 0.8 0.12 11.9 0.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF367) Cofilin_ADF PF00241.15 AAS54459.1 - 1.3e-05 25.0 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ribosomal_S13_N PF08069.7 AAS54460.1 - 1.2e-26 92.3 1.5 1.2e-26 92.3 0.3 1.6 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 AAS54460.1 - 3.8e-23 81.0 0.1 1.1e-22 79.5 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S15 OPT PF03169.10 AAS54463.1 - 1.8e-146 489.1 41.4 2.1e-146 488.9 28.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.11 AAS54464.2 - 1.5e-34 119.3 13.7 2e-34 118.9 9.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily WW PF00397.21 AAS54465.1 - 2.8e-07 30.2 0.6 4.8e-07 29.5 0.4 1.4 1 0 0 1 1 1 1 WW domain Cytadhesin_P30 PF07271.6 AAS54465.1 - 0.03 13.5 16.2 0.042 13.1 11.2 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 TraT PF05818.7 AAS54465.1 - 0.032 13.6 0.8 0.054 12.9 0.5 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Pericardin_rpt PF07054.6 AAS54465.1 - 0.75 9.7 83.7 7.4 6.5 3.3 5.5 2 1 2 4 4 4 0 Pericardin like repeat WD40 PF00400.27 AAS54466.1 - 4.3e-45 150.0 17.6 4.3e-11 42.2 0.8 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 AAS54466.1 - 2.4e-10 39.9 0.3 6.1e-10 38.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AAS54466.1 - 3.2e-08 33.0 2.8 2.5e-07 30.1 2.0 2.3 1 1 0 1 1 1 1 F-box domain PRANC PF09372.5 AAS54466.1 - 0.00083 19.2 0.2 0.0026 17.7 0.1 1.9 1 0 0 1 1 1 1 PRANC domain Nup160 PF11715.3 AAS54466.1 - 0.024 12.7 6.6 1.2 7.2 0.1 4.2 3 2 1 4 4 4 0 Nucleoporin Nup120/160 PQQ_2 PF13360.1 AAS54466.1 - 0.046 13.1 0.5 0.21 11.0 0.0 2.2 3 0 0 3 3 3 0 PQQ-like domain MgtE_N PF03448.12 AAS54466.1 - 0.069 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 MgtE intracellular N domain SMC_N PF02463.14 AAS54467.1 - 2.1e-65 220.0 0.0 4e-65 219.1 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AAS54467.1 - 3.3e-26 91.5 0.0 1.5e-25 89.5 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AAS54467.1 - 2.6e-10 40.7 15.9 1e-05 25.7 0.0 4.2 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 AAS54467.1 - 1.9e-07 30.4 0.1 4.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain CENP-F_leu_zip PF10473.4 AAS54467.1 - 0.0081 16.0 20.0 0.0081 16.0 13.9 8.4 4 3 4 8 8 8 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SbcCD_C PF13558.1 AAS54467.1 - 0.021 14.7 0.0 0.085 12.7 0.0 2.1 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Reo_sigmaC PF04582.7 AAS54467.1 - 0.048 12.8 29.8 0.089 11.9 1.5 5.6 2 2 2 6 6 6 0 Reovirus sigma C capsid protein AAA_22 PF13401.1 AAS54467.1 - 0.088 12.9 7.4 20 5.3 0.0 4.1 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.22 AAS54467.1 - 0.12 12.6 0.1 0.12 12.6 0.0 5.6 5 2 0 5 5 4 0 ABC transporter AAA_17 PF13207.1 AAS54467.1 - 0.36 11.6 4.1 4.8 8.0 0.0 4.1 3 1 0 3 3 3 0 AAA domain NPV_P10 PF05531.7 AAS54467.1 - 0.99 9.6 32.5 12 6.2 5.2 8.4 7 2 1 8 8 8 0 Nucleopolyhedrovirus P10 protein AAA_23 PF13476.1 AAS54467.1 - 1.7 8.9 110.6 0.0059 16.9 34.8 6.5 2 2 1 3 3 1 0 AAA domain Baculo_PEP_C PF04513.7 AAS54467.1 - 3.5 7.4 32.6 0.24 11.2 3.9 6.6 4 1 4 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus MtrG PF04210.8 AAS54467.1 - 5.1 6.8 6.7 10 5.8 0.0 4.2 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF3437 PF11919.3 AAS54468.2 - 1.7e-27 94.9 0.0 4.2e-27 93.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.1 AAS54468.2 - 0.003 17.7 0.3 0.93 9.8 0.0 3.8 4 0 0 4 4 4 1 HEAT repeats DUF1546 PF07571.8 AAS54468.2 - 0.072 13.2 0.0 0.28 11.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) Ras PF00071.17 AAS54469.1 - 4.5e-63 211.4 0.3 5.4e-63 211.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS54469.1 - 1.7e-19 70.4 0.1 2.5e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS54469.1 - 1.1e-18 67.0 0.1 1.3e-18 66.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AAS54469.1 - 5.4e-08 32.2 0.1 6.2e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 AAS54469.1 - 3.1e-07 29.7 0.1 3.8e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 AAS54469.1 - 8.4e-07 28.6 0.1 7e-06 25.5 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AAS54469.1 - 5.8e-06 26.2 0.1 1e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AAS54469.1 - 0.00085 18.6 0.1 0.0094 15.2 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.15 AAS54469.1 - 0.0076 14.9 0.5 0.76 8.3 0.0 2.7 1 1 1 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.1 AAS54469.1 - 0.0088 16.1 0.0 0.029 14.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 AAS54469.1 - 0.009 15.2 0.0 0.014 14.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 AAS54469.1 - 0.0097 15.9 0.3 0.024 14.6 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 AAS54469.1 - 0.018 15.2 0.0 0.44 10.7 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.18 AAS54469.1 - 0.019 13.8 0.1 0.043 12.6 0.0 1.6 2 0 0 2 2 2 0 MCM2/3/5 family AAA_29 PF13555.1 AAS54469.1 - 0.027 14.0 0.2 0.084 12.4 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.17 AAS54469.1 - 0.082 12.3 0.1 2.1 7.7 0.0 2.6 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain DUF815 PF05673.8 AAS54469.1 - 0.088 11.7 0.1 0.23 10.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) VTC PF09359.5 AAS54470.1 - 5.3e-95 317.6 0.0 7.9e-95 317.0 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 AAS54470.1 - 6.6e-29 101.5 3.8 1.2e-18 67.9 0.2 3.2 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 AAS54470.1 - 1.7e-07 31.3 5.7 1.7e-07 31.3 4.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3180 PF11377.3 AAS54470.1 - 0.13 12.1 1.8 0.21 11.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) Peptidase_C48 PF02902.14 AAS54471.2 - 2.8e-35 121.9 0.3 2.8e-35 121.9 0.2 1.8 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain SIR2 PF02146.12 AAS54472.1 - 1.7e-53 180.9 0.0 3.9e-53 179.8 0.0 1.6 2 0 0 2 2 2 1 Sir2 family zf-LYAR PF08790.6 AAS54472.1 - 0.022 14.4 0.6 0.052 13.2 0.4 1.6 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger DUF3441 PF11923.3 AAS54473.2 - 1.1e-31 108.6 0.9 1.1e-31 108.6 0.6 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3441) FbpA PF05833.6 AAS54473.2 - 3.4e-27 95.1 25.6 1.4e-20 73.3 0.0 3.5 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 AAS54473.2 - 6.3e-10 38.8 0.1 1.8e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DUF4006 PF13179.1 AAS54473.2 - 0.89 9.1 3.4 0.3 10.6 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Clat_adaptor_s PF01217.15 AAS54474.1 - 2.8e-13 49.7 0.4 3.6e-13 49.4 0.3 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ChaB PF06150.7 AAS54474.1 - 0.12 12.2 0.1 0.34 10.7 0.1 2.0 1 1 0 1 1 1 0 ChaB Bromo_TP PF07524.8 AAS54475.1 - 2.1e-07 30.5 0.1 3.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated NUC173 PF08161.7 AAS54476.2 - 3.6e-73 245.1 0.0 1e-71 240.4 0.0 2.9 2 0 0 2 2 2 1 NUC173 domain HEAT PF02985.17 AAS54476.2 - 1.4e-05 24.7 0.3 1.2 9.4 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat UME PF08064.8 AAS54476.2 - 0.072 13.0 2.3 13 5.8 0.0 4.0 5 0 0 5 5 5 0 UME (NUC010) domain Vac14_Fab1_bd PF12755.2 AAS54476.2 - 0.086 13.2 1.1 5.9 7.3 0.0 4.0 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Ribosomal_S16 PF00886.14 AAS54477.2 - 2.5e-24 84.7 0.1 3.3e-24 84.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 PDR_assoc PF08370.6 AAS54477.2 - 0.13 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Plant PDR ABC transporter associated DUF4148 PF13663.1 AAS54477.2 - 0.14 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Helicase_C_2 PF13307.1 AAS54480.1 - 7.8e-49 165.8 0.1 1.4e-48 164.9 0.1 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 AAS54480.1 - 1.3e-45 154.9 0.0 2.3e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 AAS54480.1 - 0.0021 17.9 2.6 0.11 12.3 0.0 3.0 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AAS54480.1 - 0.0091 15.5 0.1 2.8 7.4 0.0 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase AAA_22 PF13401.1 AAS54480.1 - 0.01 15.9 1.8 1.1 9.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain zf-TFIIIC PF12660.2 AAS54481.2 - 1.2e-08 34.7 0.0 2.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex WD40 PF00400.27 AAS54481.2 - 0.069 13.0 0.0 7.5 6.6 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat Patched PF02460.13 AAS54482.1 - 4.8e-57 193.4 29.4 6.6e-31 107.0 6.3 3.7 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 AAS54482.1 - 4.8e-38 130.0 9.5 4.8e-38 130.0 6.6 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Baculo_p33 PF05214.7 AAS54482.1 - 0.087 12.0 0.1 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 Baculovirus P33 MMPL PF03176.10 AAS54482.1 - 9.1 4.8 24.4 2.2 6.9 4.2 2.4 2 0 0 2 2 2 0 MMPL family PPR_2 PF13041.1 AAS54483.1 - 1.3e-12 47.4 3.7 2.1e-05 24.4 0.0 4.2 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 AAS54483.1 - 9.1e-07 28.6 0.2 0.033 14.4 0.0 5.5 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR PF01535.15 AAS54483.1 - 0.0065 16.3 7.9 1.5 8.9 0.0 5.3 6 0 0 6 6 6 2 PPR repeat Pil1 PF13805.1 AAS54484.1 - 8.9e-154 510.3 0.3 1e-153 510.2 0.2 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 AAS54484.1 - 0.032 13.5 0.7 0.053 12.8 0.5 1.5 1 0 0 1 1 1 0 FAM92 protein PCP_red PF08369.5 AAS54484.1 - 0.17 11.7 0.2 0.17 11.7 0.1 2.5 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit ThiF PF00899.16 AAS54485.1 - 0.029 14.1 0.7 0.072 12.9 0.5 1.6 2 0 0 2 2 2 0 ThiF family DEAD PF00270.24 AAS54486.1 - 3e-39 134.2 0.0 8.4e-39 132.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS54486.1 - 1.9e-19 69.2 0.0 5.5e-19 67.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 AAS54486.1 - 2.3e-12 46.2 0.0 6e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 AAS54486.1 - 0.0097 15.7 0.0 0.0097 15.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PseudoU_synth_1 PF01416.15 AAS54487.2 - 3.4e-31 107.7 0.0 7.9e-21 74.4 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase EAP30 PF04157.11 AAS54488.1 - 2.1e-48 164.4 0.0 2.3e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DivIVA PF05103.8 AAS54488.1 - 0.015 15.3 0.2 0.029 14.4 0.2 1.4 1 0 0 1 1 1 0 DivIVA protein Hat1_N PF10394.4 AAS54489.2 - 9.2e-39 133.0 0.6 1.8e-38 132.1 0.1 1.7 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 AAS54489.2 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Citrate_synt PF00285.16 AAS54491.1 - 2.2e-89 299.6 0.0 2.7e-89 299.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase MmgE_PrpD PF03972.9 AAS54492.1 - 4.2e-154 513.0 0.0 5.1e-154 512.7 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Nic96 PF04097.9 AAS54493.1 - 1.3e-224 746.8 11.8 1.7e-224 746.5 8.2 1.1 1 0 0 1 1 1 1 Nup93/Nic96 XET_C PF06955.7 AAS54493.1 - 0.11 12.2 0.0 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 Xyloglucan endo-transglycosylase (XET) C-terminus PPI_Ypi1 PF07491.6 AAS54494.1 - 2.1e-26 91.3 5.2 4e-26 90.4 3.6 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor DUF4636 PF15468.1 AAS54494.1 - 0.23 10.8 11.3 0.27 10.6 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) Hom_end_hint PF05203.11 AAS54494.1 - 0.39 10.4 4.2 0.46 10.1 2.9 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint CDC45 PF02724.9 AAS54494.1 - 0.9 7.4 9.8 1 7.3 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Atrophin-1 PF03154.10 AAS54494.1 - 3.9 5.4 11.5 4.1 5.4 8.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family SR-25 PF10500.4 AAS54494.1 - 4.1 6.8 20.3 7.1 6.0 13.7 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein JAB PF01398.16 AAS54495.1 - 1.4e-33 114.9 0.2 1.4e-33 114.9 0.1 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 AAS54495.1 - 5.7e-24 84.4 5.0 5.7e-24 84.4 3.5 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 AAS54495.1 - 8.9e-09 34.8 0.0 1.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 AAS54495.1 - 0.17 11.3 2.2 0.24 10.8 0.0 2.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) UCH PF00443.24 AAS54496.2 - 1.8e-10 40.4 0.0 8.4e-10 38.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 AAS54496.2 - 1.7e-08 34.4 0.0 3.9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_M24 PF00557.19 AAS54497.1 - 1.5e-56 191.2 0.0 2e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 AAS54497.1 - 1.3e-22 79.5 0.0 1.2e-21 76.5 0.0 2.2 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain CSTF2_hinge PF14327.1 AAS54498.2 - 7.2e-23 80.4 3.2 7.2e-23 80.4 2.2 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 AAS54498.2 - 8.4e-05 21.7 4.1 8.4e-05 21.7 2.8 3.0 2 1 1 3 3 3 1 Transcription termination and cleavage factor C-terminal APC2 PF08672.6 AAS54498.2 - 1.6 9.0 6.2 0.59 10.4 0.3 2.4 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 PAT1 PF09770.4 AAS54498.2 - 8.8 4.4 19.1 11 4.1 13.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RRM_1 PF00076.17 AAS54499.1 - 1.8e-19 69.1 0.0 4.3e-19 67.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS54499.1 - 1.4e-14 53.7 0.0 3.4e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS54499.1 - 1.9e-09 37.2 0.0 3.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 AAS54499.1 - 3.3e-09 35.8 0.7 8.7e-09 34.5 0.5 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.1 AAS54499.1 - 6.7e-07 29.2 0.9 6.7e-07 29.2 0.6 1.6 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 TFIIS_M PF07500.9 AAS54500.2 - 2.8e-30 104.7 0.9 5e-30 103.9 0.1 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 AAS54500.2 - 3.1e-17 61.9 6.3 4.9e-17 61.2 4.4 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 AAS54500.2 - 1.7e-14 53.0 2.4 3.6e-14 51.9 1.6 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF3608 PF12257.3 AAS54500.2 - 0.047 12.6 0.0 0.084 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3608) PALP PF00291.20 AAS54501.2 - 1.6e-57 195.0 0.0 3e-57 194.1 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 AAS54501.2 - 5e-15 55.0 0.1 6.3e-10 38.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain DUF1989 PF09347.5 AAS54502.2 - 3.1e-51 173.1 0.0 3.8e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Dam PF05869.6 AAS54502.2 - 0.0057 16.1 0.0 0.0088 15.5 0.0 1.2 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) Snf7 PF03357.16 AAS54503.1 - 5.3e-35 120.3 8.8 6.4e-35 120.0 6.1 1.1 1 0 0 1 1 1 1 Snf7 DUF3416 PF11896.3 AAS54503.1 - 0.92 9.4 3.2 0.46 10.4 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) Hemerythrin PF01814.18 AAS54503.1 - 0.99 9.5 5.5 2.6 8.2 1.7 2.6 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain NPV_P10 PF05531.7 AAS54503.1 - 3.3 8.0 5.9 23 5.3 0.1 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein ALAD PF00490.16 AAS54504.1 - 5.4e-114 380.4 0.0 6.6e-114 380.1 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PITH PF06201.8 AAS54505.1 - 6.1e-43 146.1 0.0 7.4e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 PITH domain PWI PF01480.12 AAS54509.2 - 0.0065 16.5 0.7 0.018 15.1 0.2 2.1 2 0 0 2 2 2 1 PWI domain PALP PF00291.20 AAS54510.1 - 2.4e-63 214.2 0.2 2.8e-63 213.9 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CTP_transf_2 PF01467.21 AAS54511.2 - 3.3e-35 121.4 0.0 4.8e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase UCH PF00443.24 AAS54512.1 - 2.7e-42 144.7 0.0 5.4e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 AAS54512.1 - 2.5e-21 75.5 4.5 2.5e-21 75.5 3.1 2.9 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 AAS54512.1 - 2.3e-19 69.9 0.1 1.9e-18 66.9 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 AAS54512.1 - 8.8e-15 54.0 0.0 4.6e-07 29.4 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain ECH PF00378.15 AAS54513.1 - 1.2e-27 96.6 0.1 3.7e-27 95.0 0.1 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 AAS54513.1 - 1.5e-17 63.8 1.3 3.9e-17 62.4 0.6 1.9 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region COMPASS-Shg1 PF05205.7 AAS54513.1 - 0.47 10.7 3.3 0.66 10.2 0.7 2.2 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Lipid_DES PF08557.5 AAS54514.2 - 8.5e-20 69.7 1.5 1.4e-19 69.0 1.0 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.19 AAS54514.2 - 2.8e-18 66.3 17.2 2.7e-17 63.0 11.9 2.1 1 1 0 1 1 1 1 Fatty acid desaturase Pkinase PF00069.20 AAS54516.1 - 9e-40 136.4 0.4 1.7e-39 135.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS54516.1 - 2e-28 99.1 0.0 3.3e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS54516.1 - 0.0016 17.4 0.0 0.0037 16.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AAS54516.1 - 0.0038 16.9 2.7 0.1 12.3 0.0 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family ORC2 PF04084.9 AAS54517.2 - 5e-106 354.2 0.0 6.4e-106 353.8 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 TFIIS_C PF01096.13 AAS54518.1 - 6.8e-22 76.8 3.2 6.8e-22 76.8 2.2 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 AAS54518.1 - 1.1e-11 44.2 2.1 2.2e-11 43.2 0.4 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 AAS54518.1 - 0.0098 15.6 5.3 0.13 12.1 0.1 2.5 2 1 0 2 2 2 1 Double zinc ribbon PhnA_Zn_Ribbon PF08274.7 AAS54518.1 - 0.011 15.5 5.8 0.78 9.5 0.2 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Terminase_GpA PF05876.7 AAS54518.1 - 0.018 13.4 1.4 0.46 8.7 0.9 2.0 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) Zn_Tnp_IS1595 PF12760.2 AAS54518.1 - 0.095 12.5 0.6 0.095 12.5 0.4 2.9 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Elf1 PF05129.8 AAS54518.1 - 0.14 11.9 0.9 10 5.8 0.0 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Baculo_LEF5_C PF11792.3 AAS54518.1 - 0.22 10.9 3.6 0.17 11.3 0.3 2.2 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain IBR PF01485.16 AAS54518.1 - 1 9.3 8.8 1.2 9.0 0.1 3.0 2 1 1 3 3 3 0 IBR domain zinc_ribbon_5 PF13719.1 AAS54518.1 - 1.2 8.8 9.7 8.2 6.1 0.7 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AAS54518.1 - 2.3 7.9 10.5 10 5.9 0.8 3.7 4 0 0 4 4 4 0 zinc-ribbon domain DUF2387 PF09526.5 AAS54518.1 - 7.1 6.6 6.9 4.8 7.1 0.3 2.6 2 2 0 2 2 2 0 Probable metal-binding protein (DUF2387) Coprogen_oxidas PF01218.13 AAS54519.1 - 1.3e-131 437.5 0.0 1.5e-131 437.3 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase zf-H2C2_2 PF13465.1 AAS54520.1 - 5.9e-06 26.3 12.6 6.8e-05 22.9 1.8 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 AAS54520.1 - 1.2e-05 25.3 17.9 0.00039 20.5 1.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS54520.1 - 0.00011 22.3 15.2 0.068 13.5 0.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 AAS54520.1 - 0.51 10.6 0.1 0.51 10.6 0.1 2.6 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-RING-like PF08746.6 AAS54520.1 - 1.4 9.0 6.0 0.37 10.8 1.4 2.0 2 0 0 2 2 2 0 RING-like domain zf-RING_2 PF13639.1 AAS54523.1 - 4.3e-11 42.4 10.1 6.7e-11 41.8 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AAS54523.1 - 7.7e-10 38.7 3.7 1.5e-09 37.8 2.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AAS54523.1 - 1.7e-05 24.5 4.4 3.6e-05 23.5 3.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 AAS54523.1 - 8.7e-05 22.1 6.0 0.00014 21.4 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AAS54523.1 - 0.00028 20.4 8.9 0.00042 19.8 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AAS54523.1 - 0.00035 20.5 8.3 0.00071 19.5 5.7 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AAS54523.1 - 0.0055 16.3 7.8 0.0089 15.7 5.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 AAS54523.1 - 0.046 13.6 6.9 0.3 11.0 4.8 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Tmpp129 PF10272.4 AAS54523.1 - 0.083 11.6 0.3 0.15 10.7 0.2 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-C3HC4_4 PF15227.1 AAS54523.1 - 0.092 12.6 8.5 0.2 11.5 5.9 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 AAS54523.1 - 0.3 10.8 5.6 0.54 10.0 3.9 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-P11 PF03854.9 AAS54523.1 - 4.1 6.9 9.4 11 5.6 5.2 2.1 1 1 1 2 2 2 0 P-11 zinc finger Ribosomal_S10 PF00338.17 AAS54524.1 - 2.2e-27 94.7 0.0 3.3e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e FtsJ PF01728.14 AAS54525.1 - 1.8e-64 217.0 0.0 2.6e-64 216.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 AAS54525.1 - 0.0049 17.4 0.0 0.05 14.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS54525.1 - 0.037 13.5 0.0 0.15 11.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain tRNA-synt_2 PF00152.15 AAS54526.1 - 4e-89 298.6 3.4 8.5e-89 297.6 0.2 2.0 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AAS54526.1 - 1.3e-11 44.1 0.1 2.5e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AAS54526.1 - 1.4e-08 34.2 0.0 0.0001 21.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 AAS54526.1 - 0.037 13.6 0.3 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) AA_permease PF00324.16 AAS54527.1 - 1e-121 406.6 37.1 1.2e-121 406.4 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS54527.1 - 6.9e-35 120.3 37.5 8.5e-35 120.1 26.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AAS54528.1 - 1.6e-120 402.7 30.6 1.8e-120 402.5 21.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS54528.1 - 6.1e-29 100.8 31.7 7.6e-29 100.5 22.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AAS54529.1 - 9.8e-128 426.4 38.9 1.2e-127 426.1 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS54529.1 - 8.1e-38 130.0 39.1 9.3e-38 129.8 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_oprn_chp PF09534.5 AAS54529.1 - 0.001 18.7 0.1 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Slx4 PF09494.5 AAS54531.1 - 4.7e-12 45.4 0.0 7.7e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease Mcp5_PH PF12814.2 AAS54532.2 - 7.6e-38 129.2 0.0 1.8e-37 127.9 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology ADIP PF11559.3 AAS54532.2 - 1e-05 25.5 13.5 1e-05 25.5 9.3 4.8 3 1 1 4 4 4 2 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.16 AAS54532.2 - 0.0011 18.8 3.6 0.0011 18.8 2.5 5.7 3 1 1 4 4 4 1 bZIP transcription factor zf-CCCH PF00642.19 AAS54533.1 - 1.7e-19 68.9 16.5 7.1e-10 38.3 0.9 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AAS54533.1 - 1.1 9.3 11.9 2.6 8.1 0.4 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type RWD PF05773.17 AAS54534.1 - 3e-22 78.6 0.3 6.8e-22 77.4 0.2 1.6 1 0 0 1 1 1 1 RWD domain Atrophin-1 PF03154.10 AAS54534.1 - 5.3 5.0 5.7 7.2 4.6 3.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family ENTH PF01417.15 AAS54535.1 - 2.1e-31 108.4 0.3 3.2e-31 107.7 0.2 1.3 1 0 0 1 1 1 1 ENTH domain Phage_T4_Ndd PF06591.6 AAS54535.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) ABC_membrane PF00664.18 AAS54536.2 - 5.7e-89 298.1 26.5 1e-47 162.9 1.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AAS54536.2 - 2.3e-50 170.4 0.0 2e-30 105.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 AAS54536.2 - 4.1e-09 35.9 6.2 0.0011 18.2 0.1 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AAS54536.2 - 1.4e-08 34.9 0.4 0.0061 16.5 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.1 AAS54536.2 - 7.4e-06 26.1 1.0 0.085 12.7 0.1 4.5 2 2 1 4 4 4 1 AAA domain AAA_29 PF13555.1 AAS54536.2 - 1.1e-05 24.9 0.1 0.013 15.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 AAS54536.2 - 1.6e-05 24.4 0.0 0.11 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 AAS54536.2 - 3.9e-05 23.5 0.0 0.32 10.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 AAS54536.2 - 0.00015 22.2 0.2 0.26 11.8 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 AAS54536.2 - 0.00053 20.3 5.3 0.0095 16.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 AAS54536.2 - 0.00059 19.0 0.1 0.29 10.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 AAS54536.2 - 0.001 19.1 0.3 1.6 8.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 AAS54536.2 - 0.003 17.0 0.7 1.5 8.2 0.1 3.1 3 0 0 3 3 3 1 AAA-like domain ArgK PF03308.11 AAS54536.2 - 0.0097 14.7 0.1 0.84 8.3 0.0 2.3 2 0 0 2 2 2 1 ArgK protein FtsK_SpoIIIE PF01580.13 AAS54536.2 - 0.0097 15.3 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 AAS54536.2 - 0.015 15.0 0.3 3.6 7.2 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B HTH_45 PF14947.1 AAS54536.2 - 0.026 14.3 0.4 0.075 12.8 0.3 1.8 1 1 0 1 1 1 0 Winged helix-turn-helix Dynamin_N PF00350.18 AAS54536.2 - 0.03 14.1 2.0 0.63 9.8 0.0 2.7 3 0 0 3 3 2 0 Dynamin family AAA_17 PF13207.1 AAS54536.2 - 0.05 14.4 0.2 3 8.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 AAS54536.2 - 0.056 13.2 7.1 0.32 10.7 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF87 Sigma54_activat PF00158.21 AAS54536.2 - 0.057 12.8 0.0 7.7 5.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 AAS54536.2 - 0.072 12.1 0.2 9.2 5.3 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 AAS54536.2 - 0.17 11.5 0.0 0.17 11.5 0.0 2.6 4 0 0 4 4 2 0 Archaeal ATPase Pkinase PF00069.20 AAS54537.1 - 7.8e-70 234.9 0.0 1.6e-69 233.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS54537.1 - 5.5e-31 107.5 0.0 1.1e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AAS54537.1 - 4.7e-05 22.5 0.1 0.0002 20.4 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AAS54537.1 - 0.00017 21.4 3.6 0.0015 18.2 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 AAS54537.1 - 0.0013 17.7 0.0 0.11 11.4 0.0 2.4 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 AAS54537.1 - 0.055 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Flocculin_t3 PF13928.1 AAS54538.1 - 9.2e-09 35.3 13.5 9.2e-09 35.3 9.4 2.2 3 0 0 3 3 3 1 Flocculin type 3 repeat ApoL PF05461.6 AAS54538.1 - 0.61 9.2 3.9 0.7 9.0 2.7 1.0 1 0 0 1 1 1 0 Apolipoprotein L BTB_2 PF02214.17 AAS54539.2 - 3.7e-10 39.8 0.1 1.4e-05 25.1 0.0 2.8 2 1 0 2 2 2 2 BTB/POZ domain CBM_14 PF01607.19 AAS54539.2 - 0.057 13.3 0.3 0.44 10.5 0.0 2.4 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain Herpes_U30 PF04523.8 AAS54540.1 - 0.037 11.4 0.4 0.047 11.1 0.3 1.2 1 0 0 1 1 1 0 Herpes virus tegument protein U30 RNase_T PF00929.19 AAS54541.1 - 9.2e-17 61.8 0.1 2.3e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 AAS54541.1 - 0.012 15.0 0.1 0.21 11.0 0.1 2.5 2 1 0 2 2 2 0 3'-5' exonuclease CBFD_NFYB_HMF PF00808.18 AAS54542.1 - 3.6e-05 23.7 0.1 6.8e-05 22.8 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AAS54542.1 - 0.058 13.5 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Med4 PF10018.4 AAS54542.1 - 8.1 5.7 8.7 0.47 9.8 0.1 2.2 1 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Nyv1_N PF09426.5 AAS54543.2 - 1.2e-60 203.2 0.1 2e-60 202.4 0.0 1.3 1 0 0 1 1 1 1 Vacuolar R-SNARE Nyv1 N terminal Synaptobrevin PF00957.16 AAS54543.2 - 6.4e-27 92.9 2.7 1.1e-26 92.2 1.9 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF2077 PF09850.4 AAS54543.2 - 0.046 13.1 1.3 0.17 11.2 0.1 2.0 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) FMO-like PF00743.14 AAS54544.1 - 5.7e-26 90.8 0.0 4.3e-15 54.9 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 AAS54544.1 - 9e-15 55.2 0.0 2.3e-13 50.7 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AAS54544.1 - 9e-11 41.2 0.0 4.2e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 AAS54544.1 - 7.1e-07 29.1 3.7 7.2e-06 25.8 0.3 3.5 3 2 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AAS54544.1 - 8.8e-06 25.7 0.0 0.00012 22.0 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AAS54544.1 - 9.6e-05 22.3 0.1 0.00023 21.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AAS54544.1 - 0.022 15.1 0.1 0.19 12.1 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AAS54544.1 - 0.082 11.9 0.0 0.66 9.0 0.0 2.0 2 0 0 2 2 2 0 Thi4 family DAO PF01266.19 AAS54544.1 - 0.12 11.3 0.0 5.4 5.8 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 AAS54544.1 - 0.15 10.4 0.0 3.5 5.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein PHD PF00628.24 AAS54546.1 - 0.0061 16.2 3.6 0.0061 16.2 2.5 1.9 2 0 0 2 2 2 1 PHD-finger Pkinase PF00069.20 AAS54547.2 - 4.3e-72 242.3 0.6 2.1e-71 240.1 0.4 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS54547.2 - 2.2e-39 135.0 0.2 1.7e-37 128.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.14 AAS54547.2 - 3.8e-20 71.0 0.0 7.3e-20 70.1 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 AAS54547.2 - 2.4e-05 23.4 0.0 3.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AAS54547.2 - 0.00014 21.0 0.0 0.00027 20.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AAS54547.2 - 0.004 16.9 0.0 0.038 13.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 AAS54547.2 - 0.017 14.3 0.1 0.028 13.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF2841 PF11001.3 AAS54549.2 - 1.2e-39 135.0 1.0 1.7e-39 134.5 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) Fungal_trans PF04082.13 AAS54550.1 - 3.1e-35 121.3 0.4 6.5e-35 120.2 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS54550.1 - 1.5e-08 34.3 9.5 3e-08 33.4 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DHHC PF01529.15 AAS54554.1 - 3.4e-24 85.1 6.0 3.3e-23 81.9 4.1 2.2 1 1 0 1 1 1 1 DHHC palmitoyltransferase K-cyclin_vir_C PF09080.5 AAS54554.1 - 0.003 17.7 2.6 0.02 15.1 0.1 2.4 2 0 0 2 2 2 1 K cyclin, C terminal EPSP_synthase PF00275.15 AAS54555.2 - 6.9e-133 443.1 0.0 1.1e-132 442.4 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 AAS54555.2 - 1.1e-99 332.6 0.0 6.2e-99 330.1 0.0 2.0 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 AAS54555.2 - 8e-61 205.5 0.0 1.8e-60 204.3 0.0 1.7 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 AAS54555.2 - 1.8e-35 122.1 0.0 2.4e-34 118.4 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 AAS54555.2 - 1.6e-23 82.5 0.0 5.1e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 AAS54555.2 - 7.2e-14 52.0 0.0 1.7e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 AAS54555.2 - 5.4e-09 35.7 0.0 1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 AAS54555.2 - 0.00037 21.2 0.0 0.0013 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AAS54555.2 - 0.00086 19.2 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AAS54555.2 - 0.05 13.9 0.0 0.73 10.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain GARS_N PF02844.10 AAS54555.2 - 0.082 13.3 0.0 0.35 11.3 0.0 2.1 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain WD40 PF00400.27 AAS54556.2 - 1.8e-11 43.4 24.1 2.7e-05 23.8 0.1 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat C1_1 PF00130.17 AAS54556.2 - 0.002 17.8 4.5 0.005 16.5 3.1 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.2 AAS54556.2 - 0.17 12.0 10.0 0.48 10.5 6.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 AAS54556.2 - 0.65 9.8 12.3 1.5 8.7 8.6 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 AAS54556.2 - 2.4 8.2 11.4 5.4 7.1 7.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CH PF00307.26 AAS54558.2 - 1.6e-69 230.7 0.1 9.4e-18 64.2 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 AAS54558.2 - 1.7e-06 28.0 1.0 3.7e-05 23.7 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 AAS54558.2 - 1e-05 25.0 0.0 0.016 14.8 0.0 3.8 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_1 PF00036.27 AAS54558.2 - 4e-05 22.6 1.4 0.08 12.2 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 AAS54558.2 - 0.013 15.2 0.5 9.5 6.4 0.0 3.6 3 0 0 3 3 3 0 EF-hand domain RRN3 PF05327.6 AAS54558.2 - 0.13 10.3 0.3 0.19 9.8 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Apc9 PF12856.2 AAS54559.1 - 3.4e-15 55.9 0.0 7.4e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 9 CDC45 PF02724.9 AAS54560.1 - 1.2e-207 690.8 0.0 1.4e-207 690.6 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Lantibiotic_a PF14867.1 AAS54561.1 - 0.061 12.5 0.1 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Lantibiotic alpha tRNA_int_endo PF01974.12 AAS54562.2 - 1.3e-22 79.4 0.1 2.2e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain AAA_5 PF07728.9 AAS54563.2 - 2.5e-125 412.7 2.9 1.3e-21 76.7 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AAS54563.2 - 1.5e-30 105.5 0.0 1.5e-10 40.8 0.0 7.5 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 AAS54563.2 - 3.3e-26 92.0 3.8 0.00051 20.2 0.0 7.6 7 0 0 7 7 7 6 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AAS54563.2 - 2.9e-21 75.6 1.9 0.0011 18.8 0.0 9.1 9 1 1 10 10 8 5 AAA domain AAA_17 PF13207.1 AAS54563.2 - 1.1e-19 71.3 9.2 0.0083 16.9 0.0 8.2 7 0 0 7 7 6 5 AAA domain Sigma54_activ_2 PF14532.1 AAS54563.2 - 3e-19 69.4 1.2 0.00018 21.5 0.0 7.5 7 0 0 7 7 7 3 Sigma-54 interaction domain Sigma54_activat PF00158.21 AAS54563.2 - 3.7e-19 68.8 0.4 0.00026 20.5 0.0 6.6 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_22 PF13401.1 AAS54563.2 - 7.9e-18 64.8 8.0 0.023 14.8 0.5 8.6 7 1 0 7 7 7 4 AAA domain AAA_33 PF13671.1 AAS54563.2 - 5.9e-17 61.8 2.7 0.056 13.3 0.0 8.3 7 2 0 7 7 7 4 AAA domain AAA_16 PF13191.1 AAS54563.2 - 1e-15 58.2 15.0 0.004 17.1 0.0 8.6 8 0 0 8 8 6 4 AAA ATPase domain Zeta_toxin PF06414.7 AAS54563.2 - 1.8e-15 56.5 0.5 0.19 10.8 0.0 8.7 9 0 0 9 9 8 4 Zeta toxin T2SE PF00437.15 AAS54563.2 - 3.3e-15 55.7 3.5 0.14 11.0 0.0 6.4 6 0 0 6 6 6 5 Type II/IV secretion system protein AAA_19 PF13245.1 AAS54563.2 - 1.5e-12 47.0 7.4 0.071 12.8 0.0 6.4 6 0 0 6 6 6 4 Part of AAA domain ABC_tran PF00005.22 AAS54563.2 - 4.1e-12 46.5 10.6 0.0013 18.9 0.0 7.2 7 0 0 7 7 6 3 ABC transporter UPF0079 PF02367.12 AAS54563.2 - 7e-12 45.0 4.8 0.047 13.3 0.0 6.5 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 AAS54563.2 - 2.1e-10 41.1 4.6 0.39 11.2 0.1 6.7 6 0 0 6 6 6 1 Miro-like protein AAA_18 PF13238.1 AAS54563.2 - 4.2e-10 40.0 22.0 0.11 12.8 0.0 8.4 8 0 0 8 8 6 4 AAA domain RNA_helicase PF00910.17 AAS54563.2 - 4.6e-10 39.6 5.0 1.7 8.8 0.0 7.5 7 0 0 7 7 7 2 RNA helicase AAA_29 PF13555.1 AAS54563.2 - 4.5e-09 35.6 0.2 1 8.9 0.0 6.0 6 0 0 6 6 6 2 P-loop containing region of AAA domain Mg_chelatase PF01078.16 AAS54563.2 - 9.5e-09 34.7 6.2 5 6.2 0.1 9.6 11 1 1 12 12 11 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 AAS54563.2 - 1.9e-08 33.6 6.3 1.2 8.3 0.0 5.7 6 0 0 6 6 6 4 Protein of unknown function, DUF258 AAA_7 PF12775.2 AAS54563.2 - 4.2e-08 32.5 4.2 0.026 13.6 0.1 4.9 5 0 0 5 5 5 2 P-loop containing dynein motor region D3 NACHT PF05729.7 AAS54563.2 - 5.2e-08 32.7 5.4 1.4 8.5 0.0 6.1 6 0 0 6 6 5 3 NACHT domain PduV-EutP PF10662.4 AAS54563.2 - 6.3e-08 32.2 4.0 0.5 9.8 0.0 6.1 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.12 AAS54563.2 - 7.7e-08 31.9 0.6 1.6 8.0 0.0 5.6 5 0 0 5 5 5 1 IstB-like ATP binding protein MobB PF03205.9 AAS54563.2 - 2.4e-07 30.5 9.1 0.93 9.1 0.1 6.6 6 0 0 6 6 6 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 AAS54563.2 - 1.1e-06 28.5 1.5 7.4 6.5 0.0 6.6 6 0 0 6 6 6 0 50S ribosome-binding GTPase AAA_28 PF13521.1 AAS54563.2 - 2.6e-06 27.5 15.2 0.27 11.1 0.0 7.0 8 0 0 8 8 6 2 AAA domain AAA_25 PF13481.1 AAS54563.2 - 6.3e-06 25.7 7.5 2.8 7.2 0.0 5.6 7 0 0 7 7 4 1 AAA domain SRP54 PF00448.17 AAS54563.2 - 6.2e-05 22.5 13.0 3.5 7.0 0.0 6.3 7 0 0 7 7 7 2 SRP54-type protein, GTPase domain RuvB_N PF05496.7 AAS54563.2 - 0.00014 20.9 5.7 0.75 8.7 0.0 5.2 7 0 0 7 7 6 2 Holliday junction DNA helicase ruvB N-terminus ATP-synt_ab PF00006.20 AAS54563.2 - 0.00038 20.0 0.1 4.8 6.6 0.0 4.2 4 1 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_6 PF12774.2 AAS54563.2 - 0.0013 18.3 0.0 6.1 6.3 0.0 5.2 6 0 0 6 6 5 0 Hydrolytic ATP binding site of dynein motor region D1 NTPase_1 PF03266.10 AAS54563.2 - 0.13 11.9 13.5 2.9 7.5 0.0 5.8 6 0 0 6 6 5 0 NTPase TRM PF02005.11 AAS54564.1 - 2e-135 451.5 0.0 2.6e-135 451.1 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 AAS54564.1 - 0.00022 20.8 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 AAS54564.1 - 0.035 14.1 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 AAS54565.2 - 6.3e-49 166.5 36.7 6.3e-49 166.5 25.4 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AAS54565.2 - 2.4e-16 59.3 8.1 2.4e-16 59.3 5.6 3.5 3 1 1 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.8 AAS54565.2 - 0.073 11.2 10.3 0.1 10.7 7.1 1.3 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 AAS54565.2 - 4.8 5.5 30.9 0.0045 15.5 2.8 2.7 3 0 0 3 3 3 0 Vacuole effluxer Atg22 like Sulfate_transp PF00916.15 AAS54566.1 - 2.4e-82 276.1 4.7 2.4e-82 276.1 3.3 1.8 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 AAS54566.1 - 3.6e-29 100.2 2.4 3.6e-29 100.2 1.7 2.6 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 AAS54566.1 - 0.003 16.9 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 AAS54566.1 - 0.023 14.6 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 STAS domain Apc4 PF12896.2 AAS54567.1 - 6.4e-43 146.5 1.5 9.8e-43 145.9 1.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 SUI1 PF01253.17 AAS54568.2 - 9.2e-15 54.2 0.0 1.6e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 SWIB PF02201.13 AAS54568.2 - 0.0062 16.1 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Ribosomal_L1 PF00687.16 AAS54569.2 - 1.7e-24 86.3 0.0 2.1e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NYN_YacP PF05991.6 AAS54569.2 - 0.14 11.9 0.0 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 YacP-like NYN domain Ribosomal_L34 PF00468.12 AAS54570.1 - 4.3e-19 67.9 9.6 6.8e-19 67.2 6.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Securin PF04856.8 AAS54572.1 - 8.9e-34 117.1 2.5 1.1e-33 116.8 1.7 1.1 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor DnaJ PF00226.26 AAS54573.1 - 7.5e-25 86.4 2.0 1.2e-24 85.7 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AAS54573.1 - 7.9e-21 73.7 0.0 2.3e-17 62.6 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AAS54573.1 - 1.9e-10 40.6 11.8 4.9e-10 39.3 8.3 1.6 1 1 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 AAS54573.1 - 0.17 12.2 2.5 0.16 12.2 0.5 1.9 2 0 0 2 2 2 0 Cytochrome c3 SprT-like PF10263.4 AAS54573.1 - 0.4 10.3 5.2 0.38 10.4 0.1 2.2 1 1 1 2 2 2 0 SprT-like family Zn_Tnp_IS1595 PF12760.2 AAS54573.1 - 3.3 7.6 9.3 2.4 8.0 1.3 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Aminotran_1_2 PF00155.16 AAS54574.1 - 4.5e-39 134.4 0.0 7e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DAO PF01266.19 AAS54574.1 - 0.0029 16.5 0.0 0.0072 15.2 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Beta_elim_lyase PF01212.16 AAS54574.1 - 0.04 13.0 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase MCPVI PF02993.9 AAS54575.2 - 0.056 13.6 2.8 0.087 12.9 1.9 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Gaa1 PF04114.9 AAS54576.1 - 6.8e-116 387.9 16.8 1.1e-108 364.1 3.5 2.1 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component SMC_N PF02463.14 AAS54578.1 - 1.6e-79 266.2 5.7 4.3e-79 264.7 4.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AAS54578.1 - 2e-28 98.7 0.0 6.3e-28 97.1 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AAS54578.1 - 1.6e-12 48.0 21.1 1.5e-06 28.3 0.3 4.5 3 2 0 4 4 4 3 AAA domain AAA_23 PF13476.1 AAS54578.1 - 7.1e-08 33.0 26.7 7.1e-08 33.0 18.5 6.6 2 2 2 4 4 4 1 AAA domain CENP-F_leu_zip PF10473.4 AAS54578.1 - 3.3e-05 23.7 34.4 0.00024 20.9 10.6 8.8 5 2 5 10 10 10 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_29 PF13555.1 AAS54578.1 - 0.00063 19.2 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain WEMBL PF05701.6 AAS54578.1 - 0.0012 17.3 46.2 0.0012 17.3 32.1 3.5 2 1 1 3 3 3 2 Weak chloroplast movement under blue light Hema_stalk PF08720.5 AAS54578.1 - 3.8 6.9 8.3 3.2 7.2 0.4 2.9 2 1 0 2 2 2 0 Influenza C hemagglutinin stalk Actin PF00022.14 AAS54580.1 - 2.6e-53 180.8 0.0 3.3e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Actin FGGY_C PF02782.11 AAS54581.2 - 6.9e-43 146.5 2.4 1.2e-42 145.7 1.6 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 AAS54581.2 - 8.2e-23 80.9 0.0 2.2e-22 79.5 0.0 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain UPF0075 PF03702.9 AAS54581.2 - 0.038 12.9 0.1 0.068 12.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) HSP70 PF00012.15 AAS54581.2 - 0.21 9.4 0.0 0.31 8.9 0.0 1.1 1 0 0 1 1 1 0 Hsp70 protein GCR1_C PF12550.3 AAS54582.2 - 2.9e-10 39.8 0.2 5.8e-10 38.8 0.2 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF3832 PF12909.2 AAS54582.2 - 0.072 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3832) Rax2 PF12768.2 AAS54584.1 - 3.2e-73 246.3 3.9 7.5e-72 241.8 0.0 4.0 3 2 1 4 4 4 1 Cortical protein marker for cell polarity TRAPPC-Trs85 PF12739.2 AAS54585.2 - 3.6e-91 305.8 0.2 4.9e-91 305.4 0.1 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF4312 PF14189.1 AAS54585.2 - 0.034 13.9 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4312) EMP70 PF02990.11 AAS54586.1 - 1.2e-192 641.0 8.6 1.5e-192 640.7 6.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF2205 PF10224.4 AAS54587.1 - 0.0013 18.2 0.3 0.0016 17.9 0.2 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) PBS_linker_poly PF00427.16 AAS54587.1 - 0.038 13.6 0.1 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide NYD-SP28_assoc PF14775.1 AAS54587.1 - 0.37 10.5 1.9 0.72 9.5 1.3 1.7 1 1 0 1 1 1 0 Sperm tail C-terminal domain IIGP PF05049.8 AAS54588.1 - 0.13 11.0 0.1 0.19 10.4 0.1 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Actin PF00022.14 AAS54589.1 - 2.2e-22 79.0 0.1 7.3e-13 47.7 0.0 2.2 1 1 0 2 2 2 2 Actin Serinc PF03348.10 AAS54590.2 - 5e-147 490.0 12.3 5.7e-147 489.8 8.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF334 PF03904.8 AAS54590.2 - 0.12 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Rad51 PF08423.6 AAS54591.1 - 8.9e-126 418.0 0.1 1.2e-125 417.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 AAS54591.1 - 1.7e-12 47.1 0.0 2.4e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 AAS54591.1 - 2.4e-09 36.7 0.1 3.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 AAS54591.1 - 4.8e-08 32.4 0.1 1.3e-07 30.9 0.0 1.8 2 1 0 2 2 2 1 KaiC HHH_5 PF14520.1 AAS54591.1 - 0.0001 22.3 0.3 0.00033 20.7 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_22 PF13401.1 AAS54591.1 - 0.0066 16.5 0.1 0.044 13.9 0.0 2.2 3 0 0 3 3 3 1 AAA domain PAXNEB PF05625.6 AAS54591.1 - 0.011 14.5 0.0 0.17 10.6 0.0 2.0 2 0 0 2 2 2 0 PAXNEB protein RNA_pol_A_CTD PF03118.10 AAS54591.1 - 0.013 14.8 0.1 0.028 13.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain Peptidase_M24 PF00557.19 AAS54592.1 - 3.4e-08 33.3 0.6 8.1e-08 32.0 0.2 1.8 1 1 1 2 2 2 1 Metallopeptidase family M24 E1_dh PF00676.15 AAS54593.1 - 8.1e-121 402.3 0.3 9.8e-121 402.0 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 AAS54593.1 - 0.00091 18.2 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 AAS54593.1 - 0.016 15.8 3.5 0.047 14.3 0.1 2.8 2 2 0 2 2 2 0 KRTAP type 7 family Ste5_C PF12194.3 AAS54594.1 - 7.4e-89 296.4 0.1 1.1e-88 295.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase Fus3-binding zf-RING_2 PF13639.1 AAS54594.1 - 5.4e-05 22.9 5.9 9.6e-05 22.1 4.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AAS54594.1 - 0.15 11.7 4.6 0.32 10.7 3.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH_4 PF15404.1 AAS54595.1 - 6.7e-69 231.1 0.0 1.5e-68 229.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.1 AAS54595.1 - 6.7e-23 79.9 0.2 1.8e-22 78.5 0.2 1.8 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 AAS54595.1 - 1.4e-05 25.2 1.1 0.0077 16.4 0.0 3.5 3 1 0 3 3 3 2 PH domain DUF1844 PF08899.6 AAS54595.1 - 0.1 12.5 0.8 2.1 8.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) PH_6 PF15406.1 AAS54595.1 - 0.13 12.2 0.3 1.6 8.8 0.0 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain COPI_assoc PF08507.5 AAS54596.1 - 5.5e-30 103.8 0.6 6e-30 103.7 0.4 1.0 1 0 0 1 1 1 1 COPI associated protein DUF2892 PF11127.3 AAS54596.1 - 3.7 7.4 10.4 1.8 8.4 3.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) 14-3-3 PF00244.15 AAS54597.1 - 1.9e-116 387.1 4.6 2.2e-116 386.9 3.2 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.6 AAS54597.1 - 0.022 14.5 0.1 0.063 13.1 0.1 1.7 1 0 0 1 1 1 0 Flagellar protein FlaF DUF885 PF05960.6 AAS54597.1 - 0.032 13.4 0.9 0.047 12.8 0.3 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) SPACA7 PF15307.1 AAS54597.1 - 0.05 13.7 3.9 3 8.0 0.1 3.0 2 1 1 3 3 3 0 Sperm acrosome-associated protein 7 AAA_12 PF13087.1 AAS54598.2 - 6.1e-58 195.4 0.0 8.7e-58 195.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AAS54598.2 - 7.6e-43 146.7 0.0 7.1e-42 143.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AAS54598.2 - 9.5e-12 44.5 5.9 2.6e-11 43.1 0.2 3.3 4 0 0 4 4 4 1 Part of AAA domain AAA_30 PF13604.1 AAS54598.2 - 4.3e-10 39.4 0.0 5.3e-05 22.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 AAS54598.2 - 3.3e-08 33.3 0.2 0.035 13.6 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 AAS54598.2 - 0.001 18.4 0.0 0.0079 15.5 0.0 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 AAS54598.2 - 0.0077 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.4 AAS54598.2 - 0.0079 15.2 1.1 0.082 11.8 0.0 2.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 AAS54598.2 - 0.011 15.0 0.0 0.25 10.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Zot PF05707.7 AAS54598.2 - 0.017 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Arch_ATPase PF01637.13 AAS54598.2 - 0.021 14.5 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 AAS54598.2 - 0.042 13.9 0.0 0.83 9.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 AAS54598.2 - 0.043 14.0 0.1 0.094 12.9 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 AAS54598.2 - 0.19 10.4 0.0 0.33 9.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Methyltransf_11 PF08241.7 AAS54600.1 - 1.9e-14 53.9 0.1 4.6e-14 52.6 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AAS54600.1 - 5.1e-13 49.2 0.2 6.2e-12 45.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS54600.1 - 1.4e-12 47.4 0.0 2.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS54600.1 - 2.8e-12 47.2 0.0 5.1e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AAS54600.1 - 4.7e-12 46.2 0.0 7.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AAS54600.1 - 1.7e-09 37.5 0.0 3e-09 36.8 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 AAS54600.1 - 3.1e-08 33.0 0.0 5.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AAS54600.1 - 9.4e-08 32.1 0.4 3.3e-07 30.3 0.3 1.8 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 AAS54600.1 - 3e-06 26.7 0.0 6.5e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 AAS54600.1 - 9.6e-06 24.7 0.0 1.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 AAS54600.1 - 0.00074 19.2 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AAS54600.1 - 0.0048 16.8 0.0 0.0073 16.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase RrnaAD PF00398.15 AAS54600.1 - 0.016 14.2 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CMAS PF02353.15 AAS54600.1 - 0.061 12.3 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 AAS54600.1 - 0.095 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GARS_C PF02843.11 AAS54600.1 - 0.097 12.8 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain FmrO PF07091.6 AAS54600.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PCMT PF01135.14 AAS54600.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Glutaredoxin PF00462.19 AAS54601.1 - 5.1e-19 68.0 0.2 8.3e-18 64.1 0.0 2.7 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin PF00085.15 AAS54601.1 - 2.4e-15 56.1 0.4 4.3e-15 55.2 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 AAS54601.1 - 4.9e-05 23.3 0.0 0.059 13.4 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 AAS54601.1 - 0.00014 21.5 0.0 0.0003 20.4 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.1 AAS54601.1 - 0.029 14.5 0.1 0.23 11.6 0.0 2.4 2 2 0 2 2 2 0 Thioredoxin-like domain Redoxin PF08534.5 AAS54601.1 - 0.059 12.9 0.2 0.38 10.3 0.1 1.9 1 1 1 2 2 2 0 Redoxin ArsC PF03960.10 AAS54601.1 - 0.14 12.2 0.0 0.49 10.4 0.0 1.9 3 0 0 3 3 3 0 ArsC family Ribosomal_60s PF00428.14 AAS54601.1 - 0.51 10.7 6.5 0.07 13.5 1.5 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Rad17 PF03215.10 AAS54602.1 - 3e-80 270.3 0.0 5e-58 197.0 0.0 2.9 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 AAS54602.1 - 2.6e-06 27.5 0.0 1.8e-05 24.8 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 AAS54602.1 - 0.028 15.2 0.0 0.15 12.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.7 AAS54602.1 - 0.05 12.6 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 AAS54602.1 - 0.085 13.0 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 AAS54602.1 - 0.18 10.5 0.1 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Sec63 PF02889.11 AAS54603.1 - 7e-177 587.2 4.9 2.6e-94 315.9 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 AAS54603.1 - 6.8e-50 168.8 0.1 4.6e-32 110.8 0.2 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 AAS54603.1 - 7e-13 48.8 0.2 2.2e-09 37.4 0.1 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AAS54603.1 - 5.6e-09 35.7 0.0 2.6e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AAS54603.1 - 2.9e-07 30.7 2.1 0.002 18.2 0.1 4.0 4 0 0 4 4 4 2 AAA domain SNF2_N PF00176.18 AAS54603.1 - 1.7e-06 27.0 0.0 9.5e-06 24.6 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_19 PF13245.1 AAS54603.1 - 0.002 17.8 0.0 0.7 9.6 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 AAS54603.1 - 0.018 14.2 0.0 5.1 6.2 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein DUF1227 PF06777.6 AAS54604.1 - 1.3e-59 200.1 0.7 3.5e-59 198.6 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 AAS54604.1 - 1.3e-50 171.1 5.3 2.6e-50 170.2 3.7 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 AAS54604.1 - 6.4e-45 153.1 0.1 2e-44 151.5 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 AAS54604.1 - 0.00045 19.7 0.2 0.16 11.4 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase AAA_22 PF13401.1 AAS54604.1 - 0.00077 19.6 1.0 7.4 6.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain PhoH PF02562.11 AAS54604.1 - 0.0034 16.6 0.2 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein SNF2_N PF00176.18 AAS54604.1 - 0.008 15.0 1.0 0.12 11.0 0.4 2.4 1 1 1 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 AAS54604.1 - 0.015 15.1 0.0 0.96 9.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 AAS54604.1 - 0.071 12.6 0.1 0.14 11.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain YtxC PF08812.6 AAS54604.1 - 0.16 11.4 0.1 0.16 11.4 0.0 2.8 3 1 1 4 4 4 0 YtxC-like family ADK PF00406.17 AAS54605.1 - 8.6e-38 129.5 0.0 1e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 AAS54605.1 - 1e-10 41.0 0.2 1.8e-10 40.2 0.2 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 AAS54605.1 - 2.6e-07 30.5 0.0 4.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AAS54605.1 - 6.3e-05 22.1 0.0 9.7e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 AAS54605.1 - 0.0012 19.6 0.0 0.0017 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 AAS54605.1 - 0.059 12.5 0.4 0.091 11.9 0.3 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 AAS54605.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain MutS_V PF00488.16 AAS54606.2 - 3.6e-78 262.2 0.1 5.3e-78 261.6 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AAS54606.2 - 1.9e-40 138.8 0.0 2.9e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 AAS54606.2 - 4.8e-33 113.5 0.0 2.3e-32 111.3 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 AAS54606.2 - 2.2e-14 53.4 0.1 5.6e-14 52.0 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 AAS54606.2 - 1.1e-12 48.1 0.0 2.4e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain II AAA_14 PF13173.1 AAS54606.2 - 0.0036 17.2 0.0 0.16 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AAS54606.2 - 0.012 15.0 0.0 0.036 13.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 AAS54606.2 - 0.029 14.7 0.1 0.13 12.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AAS54606.2 - 0.075 13.3 0.0 0.26 11.5 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.1 AAS54606.2 - 0.082 12.8 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 AAS54606.2 - 0.13 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain JmjC PF02373.17 AAS54607.2 - 8.1e-41 138.8 1.2 2e-40 137.6 0.9 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 AAS54607.2 - 1.1e-15 56.8 1.2 3.5e-15 55.2 0.8 2.0 1 0 0 1 1 1 1 jmjN domain zf-H2C2_2 PF13465.1 AAS54607.2 - 3.2e-07 30.2 11.9 5.7e-07 29.5 5.0 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 AAS54607.2 - 3.4e-07 30.2 16.5 0.0014 18.8 2.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AAS54607.2 - 6.7e-07 29.2 12.8 0.0012 19.0 0.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AAS54607.2 - 0.01 15.7 9.8 0.026 14.4 2.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AAS54607.2 - 0.1 12.7 11.8 0.06 13.5 3.1 2.8 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 AAS54607.2 - 0.34 10.8 6.7 2 8.4 4.7 2.2 1 1 0 1 1 1 0 Zinc ribbon domain zf-met PF12874.2 AAS54607.2 - 6.1 7.1 9.8 19 5.6 0.7 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PolyA_pol PF01743.15 AAS54608.1 - 6.5e-23 81.3 0.0 1.1e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 AAS54608.1 - 5.2e-10 38.7 0.0 1.3e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 AAS54608.1 - 0.0084 15.9 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative dTDP_sugar_isom PF00908.12 AAS54608.1 - 0.11 11.8 0.0 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 dTDP-4-dehydrorhamnose 3,5-epimerase E1-E2_ATPase PF00122.15 AAS54610.2 - 2.3e-16 59.5 0.0 6.1e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 AAS54610.2 - 3.3e-15 55.8 0.1 1.2e-14 53.9 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AAS54610.2 - 4.7e-14 52.9 0.0 1.2e-13 51.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AAS54610.2 - 1e-12 48.9 0.2 6.8e-11 42.9 0.1 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AAS54610.2 - 0.00099 18.7 0.5 0.0051 16.4 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase UQ_con PF00179.21 AAS54611.1 - 5.3e-47 158.7 0.0 6e-47 158.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AAS54611.1 - 9.8e-05 22.1 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 AAS54611.1 - 0.017 14.7 0.1 0.033 13.8 0.1 1.4 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 AAS54611.1 - 0.038 13.8 0.1 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain DUF3000 PF11452.3 AAS54611.1 - 0.092 11.9 0.3 0.12 11.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) RRM_1 PF00076.17 AAS54612.1 - 1.5e-85 280.8 4.6 7.4e-21 73.5 0.1 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS54612.1 - 3.8e-57 190.1 0.1 4.8e-15 55.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS54612.1 - 3e-46 155.0 0.1 3e-10 39.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 AAS54612.1 - 9.4e-23 79.6 4.6 1.7e-22 78.8 0.5 2.9 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 AAS54612.1 - 0.0068 16.1 0.7 4 7.3 0.0 3.7 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 AAS54612.1 - 0.011 15.2 2.2 1.4 8.4 0.1 3.9 4 1 0 4 4 4 0 Calcipressin PNPase PF03726.9 AAS54612.1 - 0.015 15.5 5.3 0.017 15.3 0.5 3.1 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Cauli_DNA-bind PF03310.8 AAS54612.1 - 0.034 14.0 0.1 0.098 12.5 0.0 1.8 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein OB_RNB PF08206.6 AAS54612.1 - 0.85 9.1 7.1 21 4.6 0.7 3.6 3 1 0 3 3 3 0 Ribonuclease B OB domain Transposase_24 PF03004.9 AAS54612.1 - 3.2 7.6 7.1 0.26 11.1 0.2 2.8 4 0 0 4 4 4 0 Plant transposase (Ptta/En/Spm family) SNF2_N PF00176.18 AAS54613.1 - 7.4e-75 251.5 0.5 1.7e-74 250.2 0.4 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 AAS54613.1 - 1.6e-26 92.4 0.2 1.6e-26 92.4 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Chromo PF00385.19 AAS54613.1 - 2.4e-21 75.1 4.9 3.7e-14 52.1 0.3 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 AAS54613.1 - 1.5e-15 56.7 0.0 4.4e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.26 AAS54613.1 - 0.0012 18.8 0.0 0.004 17.1 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AAS54613.1 - 0.0029 17.6 0.3 0.021 14.9 0.0 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.3 AAS54613.1 - 0.022 14.6 0.1 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ABC_tran PF00005.22 AAS54615.1 - 1.1e-33 116.4 0.0 1.6e-15 57.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 AAS54615.1 - 2.5e-14 52.5 5.9 7.5e-14 51.0 4.1 1.9 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 AAS54615.1 - 1.9e-13 51.0 9.3 0.011 15.7 0.0 4.3 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 AAS54615.1 - 1.3e-09 37.6 1.9 0.0093 15.2 0.1 3.9 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 AAS54615.1 - 1.3e-08 34.1 3.2 1.3e-08 34.1 2.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.1 AAS54615.1 - 1.5e-07 30.8 0.6 0.62 9.0 0.0 4.0 4 0 0 4 4 4 3 AAA ATPase domain Fer4_6 PF12837.2 AAS54615.1 - 1.7e-06 27.6 11.4 2.1e-06 27.3 1.6 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.24 AAS54615.1 - 8.2e-06 26.0 0.0 0.031 14.4 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 AAS54615.1 - 1.3e-05 24.4 2.7 0.05 12.7 0.0 3.2 4 0 0 4 4 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 AAS54615.1 - 2.2e-05 23.9 0.0 0.017 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AAS54615.1 - 2.8e-05 23.5 0.4 0.13 11.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 AAS54615.1 - 3.1e-05 24.0 0.0 0.0055 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AAS54615.1 - 6e-05 23.1 0.1 0.063 13.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AAS54615.1 - 0.00012 22.8 0.3 0.79 10.5 0.0 2.8 2 2 0 2 2 2 2 AAA domain Fer4_21 PF14697.1 AAS54615.1 - 0.0002 21.1 11.3 0.00048 19.9 7.8 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 AAS54615.1 - 0.00026 20.7 2.2 0.00026 20.7 1.5 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain NB-ARC PF00931.17 AAS54615.1 - 0.00032 19.6 0.0 0.06 12.2 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Fer4_7 PF12838.2 AAS54615.1 - 0.00057 20.2 1.8 0.00057 20.2 1.2 2.5 1 1 2 3 3 3 2 4Fe-4S dicluster domain AAA_18 PF13238.1 AAS54615.1 - 0.00079 19.7 0.0 1.3 9.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 AAS54615.1 - 0.00088 19.7 0.0 1.7 9.1 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 AAS54615.1 - 0.0011 18.7 2.1 0.072 12.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 AAS54615.1 - 0.0012 19.0 0.1 0.4 10.8 0.0 2.9 2 0 0 2 2 2 1 RNA helicase Fer4_10 PF13237.1 AAS54615.1 - 0.0012 18.5 1.3 0.0012 18.5 0.9 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain VirE PF05272.6 AAS54615.1 - 0.0014 18.1 0.0 0.97 8.8 0.0 2.5 2 0 0 2 2 2 1 Virulence-associated protein E MobB PF03205.9 AAS54615.1 - 0.0039 16.9 1.6 0.54 9.9 0.0 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_16 PF13484.1 AAS54615.1 - 0.0043 17.7 0.1 0.0043 17.7 0.1 2.5 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_28 PF13521.1 AAS54615.1 - 0.0059 16.5 0.4 1.9 8.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.1 AAS54615.1 - 0.0061 16.1 0.2 0.14 11.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Fer4_3 PF12798.2 AAS54615.1 - 0.0062 17.0 5.0 0.0062 17.0 3.4 2.6 2 0 0 2 2 1 1 4Fe-4S binding domain SRP54 PF00448.17 AAS54615.1 - 0.0076 15.7 2.8 0.31 10.4 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 AAS54615.1 - 0.01 15.7 0.0 1.7 8.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.10 AAS54615.1 - 0.015 14.0 0.2 1.6 7.3 0.0 2.4 2 1 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 AAS54615.1 - 0.016 15.0 0.2 5.8 6.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain Fer4_9 PF13187.1 AAS54615.1 - 0.018 15.3 13.2 0.076 13.2 9.2 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain SbcCD_C PF13558.1 AAS54615.1 - 0.022 14.6 0.1 14 5.6 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_4 PF12800.2 AAS54615.1 - 0.024 14.9 2.2 0.024 14.9 1.5 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_5 PF07728.9 AAS54615.1 - 0.024 14.3 1.2 0.19 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 AAS54615.1 - 0.027 14.1 0.2 0.34 10.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 AAS54615.1 - 0.039 14.2 4.5 0.13 12.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 AAS54615.1 - 0.052 13.1 0.7 0.79 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 AAS54615.1 - 0.061 13.3 8.2 0.23 11.5 5.8 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_10 PF12846.2 AAS54615.1 - 0.11 11.9 0.0 13 5.1 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 AAS54615.1 - 0.11 11.3 0.0 4.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_13 PF13166.1 AAS54615.1 - 0.12 10.8 0.1 0.5 8.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 AAS54615.1 - 0.13 12.2 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.4 AAS54615.1 - 0.24 9.9 0.1 8.4 4.8 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 AAS54615.1 - 0.29 10.9 1.8 0.47 10.2 0.0 2.1 2 0 0 2 2 1 0 Part of AAA domain PduV-EutP PF10662.4 AAS54615.1 - 0.34 10.3 3.2 0.56 9.6 0.1 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_17 PF13534.1 AAS54615.1 - 2.4 8.5 10.7 0.097 13.0 0.8 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 AAS54615.1 - 3.5 8.2 8.1 0.11 13.1 0.7 2.2 2 0 0 2 2 1 0 4Fe-4S single cluster domain Fer4_18 PF13746.1 AAS54615.1 - 4.7 7.7 10.2 0.2 12.0 2.5 2.0 1 1 0 2 2 1 0 4Fe-4S dicluster domain Phosphodiest PF01663.17 AAS54616.2 - 2.6e-13 50.0 0.2 4.8e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 AAS54616.2 - 2.7e-05 23.6 0.5 4.4e-05 22.9 0.4 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 AAS54616.2 - 0.029 13.5 0.0 0.07 12.2 0.0 1.6 2 0 0 2 2 2 0 Sulfatase Aminotran_1_2 PF00155.16 AAS54617.2 - 6.4e-65 219.4 0.0 7.6e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 AAS54617.2 - 0.00031 19.6 0.0 0.00057 18.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 AAS54617.2 - 0.0018 16.8 0.0 0.003 16.1 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.16 AAS54617.2 - 0.018 14.2 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Acetyltransf_7 PF13508.1 AAS54618.1 - 1.5e-09 37.8 0.0 2.1e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AAS54618.1 - 4.7e-09 36.1 0.0 7.4e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 AAS54618.1 - 5.4e-07 29.5 0.0 6.9e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AAS54618.1 - 0.0016 18.3 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AAS54618.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AAS54618.1 - 0.024 14.7 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FTR1 PF03239.9 AAS54619.1 - 1.4e-89 300.0 12.1 1.6e-89 299.8 8.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3816 PF12822.2 AAS54619.1 - 0.34 10.7 15.7 0.13 12.1 7.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) LSM PF01423.17 AAS54620.1 - 6.1e-17 60.9 0.0 6.7e-17 60.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.12 AAS54620.1 - 0.12 12.0 0.2 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain Glyco_transf_20 PF00982.16 AAS54622.1 - 6.8e-145 483.1 0.0 8.9e-145 482.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 AAS54622.1 - 7e-79 264.0 0.0 1.1e-78 263.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_trans_4_4 PF13579.1 AAS54622.1 - 0.0018 18.4 4.7 0.0025 17.9 2.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 AAS54622.1 - 0.017 14.5 0.0 0.064 12.6 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferases group 1 Cohesin_load PF10345.4 AAS54623.1 - 1e-79 268.4 9.9 1.4e-79 267.9 6.9 1.1 1 0 0 1 1 1 1 Cohesin loading factor TBP PF00352.16 AAS54624.1 - 8.4e-70 230.1 0.1 4e-35 119.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 AAS54624.1 - 0.00015 21.7 0.1 0.61 10.1 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3378) Flagellar_rod PF05149.7 AAS54625.2 - 0.002 17.3 2.0 0.002 17.3 1.4 2.4 3 0 0 3 3 3 1 Paraflagellar rod protein OSCP PF00213.13 AAS54625.2 - 0.0037 17.1 6.1 0.69 9.7 0.1 3.8 3 1 1 4 4 4 1 ATP synthase delta (OSCP) subunit Spectrin PF00435.16 AAS54625.2 - 0.016 15.4 1.1 0.016 15.4 0.8 2.7 2 0 0 2 2 2 0 Spectrin repeat RasGAP_C PF03836.10 AAS54625.2 - 0.028 14.0 0.3 0.028 14.0 0.2 2.9 3 0 0 3 3 3 0 RasGAP C-terminus MutS_III PF05192.13 AAS54625.2 - 0.061 13.0 4.0 0.091 12.5 2.6 1.4 1 1 0 1 1 1 0 MutS domain III DUF2935 PF11155.3 AAS54625.2 - 0.062 13.3 0.7 0.062 13.3 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Med9 PF07544.8 AAS54625.2 - 0.074 12.7 0.5 0.074 12.7 0.4 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Phage_lysis PF03245.8 AAS54625.2 - 0.14 12.1 5.1 2 8.3 0.6 2.4 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein LXG PF04740.7 AAS54625.2 - 0.15 11.8 6.4 0.041 13.6 1.5 2.0 2 0 0 2 2 2 0 LXG domain of WXG superfamily TPR_MLP1_2 PF07926.7 AAS54625.2 - 0.33 10.7 13.4 1.7 8.4 0.4 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Laminin_I PF06008.9 AAS54625.2 - 0.51 9.6 15.3 0.16 11.2 1.2 2.7 3 0 0 3 3 3 0 Laminin Domain I Tektin PF03148.9 AAS54625.2 - 0.53 8.7 13.2 0.48 8.8 1.6 2.3 2 0 0 2 2 2 0 Tektin family NYD-SP28_assoc PF14775.1 AAS54625.2 - 1.8 8.3 8.3 0.053 13.2 0.8 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain Occludin_ELL PF07303.8 AAS54625.2 - 2 9.1 10.8 0.85 10.3 0.7 2.8 3 0 0 3 3 2 0 Occludin homology domain GrpE PF01025.14 AAS54625.2 - 3.4 7.1 11.1 6 6.3 0.9 2.6 2 0 0 2 2 2 0 GrpE TBPIP PF07106.8 AAS54625.2 - 4.7 6.7 13.5 0.073 12.6 1.3 2.9 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMPIT PF07851.8 AAS54625.2 - 5.5 5.9 8.5 1.3 8.0 0.9 2.2 2 0 0 2 2 2 0 TMPIT-like protein Metallophos PF00149.23 AAS54626.2 - 1.3e-40 138.9 0.4 1.6e-40 138.6 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AAS54626.2 - 0.00013 21.8 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain KaiC PF06745.8 AAS54627.1 - 1.1e-06 27.9 0.0 1.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 AAS54627.1 - 0.00086 18.7 0.1 0.0039 16.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 AAS54627.1 - 0.0056 15.7 0.0 0.0085 15.1 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.6 AAS54627.1 - 0.012 14.5 0.1 0.025 13.4 0.0 1.5 2 0 0 2 2 2 0 Rad51 AAA_24 PF13479.1 AAS54627.1 - 0.039 13.5 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AAS54627.1 - 0.081 13.0 0.0 0.46 10.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 AAS54627.1 - 0.14 10.9 0.1 0.27 10.0 0.0 1.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain UCH PF00443.24 AAS54629.2 - 1.9e-55 187.8 2.1 3e-55 187.2 1.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AAS54629.2 - 4.5e-11 42.7 3.4 7.4e-10 38.7 2.3 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MgtE_N PF03448.12 AAS54629.2 - 0.016 15.4 0.2 0.036 14.3 0.1 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain Aminotran_1_2 PF00155.16 AAS54631.1 - 6.6e-27 94.4 0.0 7.9e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 AAS54631.1 - 1.8e-05 23.5 0.0 9e-05 21.2 0.0 2.0 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase PET122 PF05476.6 AAS54632.1 - 1.1e-53 182.1 0.0 1.3e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 PET122 DUF2267 PF10025.4 AAS54632.1 - 0.052 13.6 0.0 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) 60KD_IMP PF02096.15 AAS54633.1 - 7.8e-37 126.8 0.7 7.8e-37 126.8 0.5 1.9 2 0 0 2 2 2 1 60Kd inner membrane protein RhoGAP PF00620.22 AAS54634.1 - 3.4e-40 137.1 0.1 1.4e-39 135.1 0.0 2.2 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 AAS54634.1 - 3.5e-30 105.1 0.4 1.7e-29 102.8 0.1 2.4 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 AAS54634.1 - 7.3e-18 64.5 4.3 1.4e-17 63.6 0.2 3.5 3 0 0 3 3 3 1 RasGEF N-terminal motif PH PF00169.24 AAS54634.1 - 0.00013 22.1 0.0 0.00042 20.4 0.0 1.9 1 0 0 1 1 1 1 PH domain UPF0160 PF03690.8 AAS54635.1 - 4e-121 404.3 0.0 4.7e-121 404.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) CR6_interact PF10147.4 AAS54636.1 - 0.018 14.3 1.7 0.024 13.9 1.2 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF3738 PF12543.3 AAS54636.1 - 0.022 14.3 0.2 0.029 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3738) Val_tRNA-synt_C PF10458.4 AAS54636.1 - 4.9 7.3 9.9 5.2 7.2 0.3 3.5 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Sec34 PF04136.10 AAS54637.1 - 6.4e-20 71.4 0.8 6.4e-20 71.4 0.5 3.3 4 0 0 4 4 4 1 Sec34-like family FAM92 PF06730.6 AAS54637.1 - 0.0097 15.2 1.3 0.028 13.7 0.3 2.1 2 0 0 2 2 2 1 FAM92 protein IFT57 PF10498.4 AAS54637.1 - 0.016 14.0 2.8 0.087 11.5 0.7 2.4 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 DOG1 PF14144.1 AAS54637.1 - 0.48 10.5 2.5 2.8 8.0 0.3 3.3 3 0 0 3 3 3 0 Seed dormancy control BLOC1_2 PF10046.4 AAS54637.1 - 3.2 7.9 8.9 0.29 11.2 0.4 3.6 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Occludin_ELL PF07303.8 AAS54637.1 - 8.1 7.2 11.8 1.3 9.7 0.2 4.3 5 1 1 6 6 6 0 Occludin homology domain Tbf5 PF06331.7 AAS54638.1 - 3.1e-28 97.3 0.0 3.5e-28 97.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Clathrin PF00637.15 AAS54639.1 - 1.9e-28 98.8 0.6 6e-28 97.2 0.2 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 AAS54639.1 - 0.0013 18.5 0.2 0.01 15.7 0.2 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat Vps39_1 PF10366.4 AAS54639.1 - 0.0013 18.6 0.1 0.0013 18.6 0.0 2.7 3 1 1 4 4 4 1 Vacuolar sorting protein 39 domain 1 DDE_1 PF03184.14 AAS54640.2 - 2.2e-65 219.8 0.0 3.4e-65 219.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 AAS54640.2 - 2e-11 43.5 0.2 6.5e-11 41.8 0.2 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.1 AAS54640.2 - 0.19 12.5 0.1 0.19 12.5 0.1 2.8 4 0 0 4 4 4 0 Homeodomain-like domain Stn1 PF10451.4 AAS54641.1 - 8.6e-87 290.1 0.0 1.2e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Stn1_C PF12659.2 AAS54641.1 - 4.1e-37 126.8 0.1 7.8e-37 125.8 0.1 1.5 1 0 0 1 1 1 1 Telomere capping C-terminal wHTH Methyltransf_8 PF05148.10 AAS54642.1 - 1.2e-66 224.4 1.2 5.1e-65 219.1 0.3 2.3 1 1 1 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 AAS54642.1 - 5.5e-07 29.9 0.7 2.1e-06 28.1 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 AAS54642.1 - 0.0042 16.6 2.9 0.0098 15.4 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 AAS54642.1 - 0.01 15.4 1.3 0.044 13.4 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 AAS54642.1 - 0.087 13.2 0.3 0.65 10.3 0.1 2.5 2 1 0 2 2 2 0 Methyltransferase domain DUF846 PF05832.7 AAS54643.1 - 2.7e-45 153.5 0.8 3.4e-45 153.2 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Cyt_c_ox_IV PF12270.3 AAS54643.1 - 8.2 6.1 7.2 0.68 9.6 0.5 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV SSF PF00474.12 AAS54645.2 - 8.4e-06 24.6 32.3 7.8e-05 21.4 22.4 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family CBFD_NFYB_HMF PF00808.18 AAS54646.1 - 5.7e-12 45.5 0.3 1e-11 44.6 0.2 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AAS54646.1 - 0.047 13.8 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 EVI2A PF05399.6 AAS54646.1 - 0.08 12.1 0.0 0.094 11.9 0.0 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) SecE PF00584.15 AAS54647.1 - 1.4e-11 43.7 0.0 1.6e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Nop52 PF05997.7 AAS54648.1 - 1.1e-64 217.7 0.0 1.3e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 NTR2 PF15458.1 AAS54648.1 - 0.043 13.0 0.1 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Nineteen complex-related protein 2 TAN PF11640.3 AAS54648.1 - 0.081 12.6 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Slu7 PF11708.3 AAS54649.1 - 2.2e-22 80.0 1.9 5.2e-15 55.8 0.8 3.1 1 1 1 2 2 2 2 Pre-mRNA splicing Prp18-interacting factor SPX PF03105.14 AAS54650.1 - 0.027 14.2 1.0 5.7 6.6 0.0 2.9 2 1 1 3 3 3 0 SPX domain Flavi_NS2B PF01002.14 AAS54650.1 - 0.077 12.5 1.2 0.16 11.5 0.5 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS2B DUF997 PF06196.7 AAS54650.1 - 0.6 9.6 6.0 1.5 8.3 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF997) SPT2 PF08243.6 AAS54651.1 - 3.9e-25 88.4 25.8 3.9e-25 88.4 17.9 2.3 2 1 1 3 3 3 1 SPT2 chromatin protein Rad4 PF03835.10 AAS54652.2 - 1.6e-34 118.4 0.2 2.5e-34 117.7 0.1 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 AAS54652.2 - 2.8e-27 94.2 0.7 4.2e-27 93.6 0.1 1.6 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 AAS54652.2 - 4.3e-18 64.5 0.0 8.3e-18 63.6 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 AAS54652.2 - 3.4e-07 30.4 0.1 1.6e-06 28.3 0.0 2.3 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 AAS54652.2 - 0.00065 19.8 0.0 0.0021 18.2 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily Corona_5a PF06336.6 AAS54652.2 - 0.11 12.4 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Coronavirus 5a protein CK_II_beta PF01214.13 AAS54653.1 - 3.1e-72 241.9 0.0 3.9e-72 241.6 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HSCB_C PF07743.8 AAS54654.1 - 1.6e-17 63.6 2.1 3.2e-17 62.7 1.5 1.5 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 AAS54654.1 - 4.6e-09 35.8 0.0 1.2e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain ATE_C PF04377.10 AAS54655.1 - 2.4e-43 147.2 0.0 4.7e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 AAS54655.1 - 1.6e-22 79.0 4.1 1.7e-22 79.0 1.4 2.2 2 1 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Dicty_REP PF05086.7 AAS54656.1 - 0.12 10.0 0.1 0.18 9.4 0.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Aminotran_1_2 PF00155.16 AAS54657.1 - 7.8e-20 71.1 0.0 1.1e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 AAS54657.1 - 0.004 16.2 0.0 0.0068 15.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family WD40 PF00400.27 AAS54658.2 - 9.2e-41 136.3 12.4 1.3e-09 37.5 0.0 7.8 7 0 0 7 7 7 5 WD domain, G-beta repeat HIRA_B PF09453.5 AAS54658.2 - 1.4e-08 34.0 0.0 1.4e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 HIRA B motif Hira PF07569.6 AAS54658.2 - 3.9e-08 32.7 0.1 9.1e-08 31.5 0.1 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split IKI3 PF04762.7 AAS54658.2 - 0.076 10.8 0.3 1.3 6.7 0.1 2.8 2 1 1 3 3 3 0 IKI3 family Aconitase PF00330.15 AAS54659.2 - 1.8e-187 623.4 0.1 2.2e-187 623.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AAS54659.2 - 1.9e-44 150.9 0.0 3.5e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain SHD1 PF03983.7 AAS54660.2 - 9.4e-36 121.3 0.3 1.8e-35 120.4 0.2 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 AAS54660.2 - 3.9e-34 115.8 6.4 5.3e-13 48.1 0.1 4.5 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 AAS54660.2 - 5.4e-31 105.9 8.1 1.5e-11 43.6 0.2 4.5 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 AAS54660.2 - 7.8e-24 82.9 1.1 2.7e-06 26.7 0.1 4.4 4 0 0 4 4 4 3 Variant SH3 domain DUF3104 PF11302.3 AAS54660.2 - 0.0015 17.8 0.1 0.0048 16.2 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3104) SH3_3 PF08239.6 AAS54660.2 - 0.0017 18.5 0.6 0.067 13.3 0.0 2.6 2 0 0 2 2 2 1 Bacterial SH3 domain Periviscerokin PF08259.6 AAS54660.2 - 0.15 12.1 9.2 0.65 10.2 0.2 5.2 5 0 0 5 5 5 0 Periviscerokinin family DUF950 PF06106.6 AAS54660.2 - 0.18 11.8 0.0 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Staphylococcus protein of unknown function (DUF950) DUF962 PF06127.6 AAS54661.2 - 2.4e-23 81.8 0.0 4.2e-23 81.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) zf-C2H2 PF00096.21 AAS54662.2 - 2.6e-09 36.8 15.1 0.00016 21.8 2.9 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AAS54662.2 - 1.5e-06 28.2 5.8 4.5e-06 26.6 0.8 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 AAS54662.2 - 5e-05 23.0 5.3 0.16 11.8 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 AAS54662.2 - 0.00052 20.1 14.2 0.019 15.2 0.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 AAS54662.2 - 0.0076 16.4 1.8 3.7 7.8 0.0 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AAS54662.2 - 0.023 14.8 2.7 2.7 8.2 0.0 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rad9_Rad53_bind PF08605.5 AAS54663.1 - 5.6e-44 149.1 0.1 1.4e-43 147.8 0.1 1.7 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 AAS54663.1 - 7.9e-09 35.5 0.0 2.6e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Septin PF00735.13 AAS54665.1 - 2.8e-81 272.6 2.5 1.1e-80 270.6 1.7 1.8 1 1 0 1 1 1 1 Septin Dynamin_N PF00350.18 AAS54665.1 - 0.00028 20.7 0.0 0.00065 19.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family AAA_17 PF13207.1 AAS54665.1 - 0.00042 21.1 0.4 0.003 18.3 0.0 2.5 2 2 0 2 2 2 1 AAA domain T2SE PF00437.15 AAS54665.1 - 0.00085 18.2 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 AAS54665.1 - 0.0011 19.1 0.0 0.0042 17.2 0.0 1.9 1 1 1 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 AAS54665.1 - 0.0031 17.0 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.15 AAS54665.1 - 0.0037 15.9 0.4 0.016 13.9 0.0 2.1 2 1 0 2 2 2 1 G-protein alpha subunit ABC_tran PF00005.22 AAS54665.1 - 0.0049 17.1 0.4 0.015 15.6 0.1 2.1 2 1 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.18 AAS54665.1 - 0.005 16.7 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 AAS54665.1 - 0.0053 16.2 0.1 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 AAS54665.1 - 0.0061 17.0 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_10 PF12846.2 AAS54665.1 - 0.0077 15.7 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain Pox_A32 PF04665.7 AAS54665.1 - 0.0083 15.4 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_18 PF13238.1 AAS54665.1 - 0.0089 16.3 0.1 0.054 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 AAS54665.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 AAS54665.1 - 0.017 14.5 0.1 0.055 12.9 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 AAS54665.1 - 0.024 14.3 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 AAS54665.1 - 0.024 14.4 0.0 0.059 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 AAS54665.1 - 0.04 12.7 0.0 0.094 11.5 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Arch_ATPase PF01637.13 AAS54665.1 - 0.056 13.1 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 AAS54665.1 - 0.071 13.2 0.0 0.45 10.7 0.0 2.4 2 0 0 2 2 1 0 RNA helicase AAA_29 PF13555.1 AAS54665.1 - 0.12 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 AAS54665.1 - 0.45 10.8 4.2 1.5 9.0 3.0 2.0 1 1 0 1 1 1 0 AAA domain PMR5N PF14416.1 AAS54666.2 - 0.093 12.7 0.1 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 PMR5 N terminal Domain F-box-like PF12937.2 AAS54667.2 - 1.3e-07 31.2 0.5 2.7e-07 30.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AAS54667.2 - 5.2e-07 29.1 0.2 1.1e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 AAS54667.2 - 0.63 10.0 6.4 0.22 11.5 0.6 2.7 2 1 2 4 4 4 0 PRANC domain PRKCSH-like PF12999.2 AAS54668.2 - 1.2e-46 158.5 1.1 1.2e-46 158.5 0.8 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 AAS54668.2 - 3.1e-21 75.4 0.0 6e-20 71.2 0.0 2.5 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 AAS54668.2 - 1.2e-07 32.4 0.1 3.5e-07 30.9 0.0 1.9 2 0 0 2 2 1 1 Glucosidase II beta subunit-like protein CENP-Q PF13094.1 AAS54668.2 - 0.0029 17.6 8.0 0.084 12.9 0.3 2.4 2 0 0 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit Spt20 PF12090.3 AAS54668.2 - 0.0052 16.1 0.1 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Spt20 family T4SS PF07996.6 AAS54668.2 - 0.0059 16.4 5.5 0.035 13.9 0.1 2.5 2 1 0 2 2 2 1 Type IV secretion system proteins FliJ PF02050.11 AAS54668.2 - 0.0078 16.2 10.5 0.037 14.0 0.9 2.8 2 0 0 2 2 2 1 Flagellar FliJ protein Spc7 PF08317.6 AAS54668.2 - 0.0099 14.5 4.8 0.041 12.5 0.1 2.3 2 0 0 2 2 2 1 Spc7 kinetochore protein Cep57_MT_bd PF06657.8 AAS54668.2 - 0.012 15.5 3.0 3.3 7.7 0.2 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 GAS PF13851.1 AAS54668.2 - 0.012 14.8 9.5 0.13 11.4 1.1 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2884 PF11101.3 AAS54668.2 - 0.017 14.5 1.2 0.28 10.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2884) DUF1351 PF07083.6 AAS54668.2 - 0.028 14.0 1.3 0.35 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) DivIC PF04977.10 AAS54668.2 - 0.048 13.1 3.2 0.09 12.2 0.3 2.4 2 0 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.6 AAS54668.2 - 0.077 12.9 2.2 0.66 9.9 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.7 AAS54668.2 - 0.094 12.4 11.0 0.16 11.6 1.2 2.9 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein COG2 PF06148.6 AAS54668.2 - 0.14 11.9 6.8 0.73 9.7 0.3 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 WXG100 PF06013.7 AAS54668.2 - 0.14 12.1 3.1 19 5.3 0.4 3.3 4 0 0 4 4 3 0 Proteins of 100 residues with WXG CENP-F_leu_zip PF10473.4 AAS54668.2 - 0.16 11.8 8.2 0.2 11.5 0.6 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.15 AAS54668.2 - 0.34 10.6 6.9 2.6 7.8 0.8 2.7 2 0 0 2 2 2 0 Prefoldin subunit Mnd1 PF03962.10 AAS54668.2 - 0.69 9.5 8.4 1.3 8.6 0.7 2.3 2 0 0 2 2 2 0 Mnd1 family BBS2_C PF14782.1 AAS54668.2 - 1 7.8 5.2 5.5 5.4 0.4 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal Uds1 PF15456.1 AAS54668.2 - 1.3 8.9 9.1 0.56 10.2 1.0 2.5 2 0 0 2 2 2 0 Up-regulated During Septation FlxA PF14282.1 AAS54668.2 - 1.8 8.5 8.8 1 9.3 2.9 2.3 2 0 0 2 2 2 0 FlxA-like protein CRF1 PF10380.4 AAS54669.1 - 3.8e-35 120.9 3.5 4.6e-35 120.6 0.3 2.9 2 0 0 2 2 2 1 Transcription factor CRF1 Toxin_63 PF15541.1 AAS54669.1 - 0.058 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative toxin 63 WD40 PF00400.27 AAS54670.2 - 2.7e-67 220.4 10.1 9.6e-09 34.7 0.0 11.2 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.6 AAS54670.2 - 1.7e-49 167.0 0.3 2.9e-49 166.3 0.2 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 AAS54670.2 - 1.4e-08 33.4 4.4 0.015 13.4 0.3 5.8 4 1 3 7 7 7 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AAS54670.2 - 3.6e-06 25.9 1.5 0.026 13.2 0.0 5.0 2 2 2 4 4 4 1 Nup133 N terminal like Coatomer_WDAD PF04053.9 AAS54670.2 - 1.7e-05 23.7 0.5 0.28 9.9 0.0 3.1 3 0 0 3 3 3 2 Coatomer WD associated region Cytochrom_D1 PF02239.11 AAS54670.2 - 0.0062 14.8 0.5 1.4 7.1 0.0 3.3 3 1 1 4 4 4 1 Cytochrome D1 heme domain Hira PF07569.6 AAS54670.2 - 0.098 11.8 1.3 2.2 7.4 0.0 3.6 3 2 1 5 5 5 0 TUP1-like enhancer of split Rsa3 PF14615.1 AAS54671.1 - 4.3e-19 67.5 0.0 7.6e-19 66.7 0.0 1.4 1 0 0 1 1 1 1 Ribosome-assembly protein 3 Adeno_PVIII PF01310.13 AAS54671.1 - 0.23 11.2 1.7 0.32 10.7 1.2 1.1 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII PLRV_ORF5 PF01690.12 AAS54671.1 - 0.63 9.1 8.5 0.7 8.9 5.9 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF702 PF05142.7 AAS54671.1 - 1 9.5 4.4 1.4 9.0 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) BNIP2 PF12496.3 AAS54671.1 - 1.7 8.7 7.4 2.6 8.2 5.2 1.4 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Pap_E4 PF02711.9 AAS54671.1 - 2.4 9.0 10.4 8 7.3 7.2 1.9 1 1 0 1 1 1 0 E4 protein Presenilin PF01080.12 AAS54671.1 - 3.2 6.4 6.7 3.6 6.3 4.7 1.3 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.2 AAS54671.1 - 5.1 4.6 10.5 5.8 4.4 7.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S64 PF08192.6 AAS54671.1 - 6.2 5.0 9.5 6.9 4.8 6.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 VIT1 PF01988.14 AAS54672.2 - 2.8e-57 193.6 0.3 3.3e-57 193.4 0.2 1.0 1 0 0 1 1 1 1 VIT family Histone PF00125.19 AAS54673.1 - 2.4e-22 78.8 0.3 3.5e-22 78.3 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AAS54673.1 - 7.6e-06 25.9 0.1 7.6e-06 25.9 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 AAS54673.1 - 0.0016 18.6 0.0 0.0029 17.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 AAS54673.1 - 0.036 12.7 3.4 0.047 12.3 2.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF601 PF04642.7 AAS54673.1 - 0.073 12.4 6.4 0.086 12.1 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 DUF1018 PF06252.7 AAS54673.1 - 0.13 12.8 0.6 0.17 12.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Histone PF00125.19 AAS54674.1 - 3.3e-26 91.1 0.0 5.3e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AAS54674.1 - 2.3e-06 27.5 0.0 3.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-C2H2 PF00096.21 AAS54676.2 - 9.5e-13 47.6 6.5 1.1e-05 25.4 0.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AAS54676.2 - 7.5e-10 38.6 8.0 3.4e-06 27.0 0.3 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AAS54676.2 - 3.8e-09 36.2 5.7 0.00017 21.7 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 AAS54676.2 - 1.3e-06 28.3 3.7 0.0018 18.3 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AAS54676.2 - 9.3e-06 25.6 0.6 0.051 13.7 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AAS54676.2 - 0.0023 17.7 2.9 1.2 9.1 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 AAS54676.2 - 0.0028 17.7 1.8 0.57 10.3 0.2 2.6 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 AAS54676.2 - 0.003 17.1 3.6 0.12 12.0 0.0 2.6 2 0 0 2 2 2 1 zinc-finger of a C2HC-type RebB PF11747.3 AAS54676.2 - 0.0072 16.1 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Killing trait zf-FCS PF06467.9 AAS54676.2 - 0.017 14.7 0.9 1.4 8.6 0.3 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif UPF0547 PF10571.4 AAS54676.2 - 0.019 14.6 4.1 0.084 12.5 0.1 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-H2C2_5 PF13909.1 AAS54676.2 - 0.034 14.3 6.6 0.38 11.0 1.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.10 AAS54676.2 - 0.058 13.1 4.4 1.6 8.5 0.6 2.8 1 1 1 2 2 2 0 BED zinc finger DUF2256 PF10013.4 AAS54676.2 - 0.061 13.0 1.4 0.66 9.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.2 AAS54676.2 - 0.085 12.9 1.1 12 6.0 0.0 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-CHY PF05495.7 AAS54676.2 - 0.6 10.3 3.8 1.2 9.3 0.3 2.5 2 1 0 2 2 2 0 CHY zinc finger ADK PF00406.17 AAS54677.1 - 2.7e-59 199.3 0.0 3.3e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 AAS54677.1 - 8.8e-14 50.8 0.0 2.3e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 AAS54677.1 - 6.2e-06 26.1 0.0 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AAS54677.1 - 0.00033 21.4 0.0 0.00067 20.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AAS54677.1 - 0.0019 18.5 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AAS54677.1 - 0.066 13.3 0.0 2 8.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 AAS54677.1 - 0.082 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AAS54677.1 - 0.11 11.5 0.4 0.22 10.5 0.1 1.7 2 1 0 2 2 2 0 Zeta toxin CFIA_Pcf11 PF11526.3 AAS54680.1 - 1.2e-30 105.4 4.6 3.5e-30 103.9 3.2 1.8 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.14 AAS54680.1 - 0.017 14.7 1.1 0.13 11.8 0.0 2.9 3 0 0 3 3 3 0 VHS domain Mito_carr PF00153.22 AAS54681.1 - 2.7e-28 97.5 0.9 2.3e-14 52.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_4 PF02390.12 AAS54682.1 - 1.1e-59 200.8 0.1 1.6e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 AAS54682.1 - 3.2e-06 26.8 0.0 5.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AAS54682.1 - 5.6e-06 26.9 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AAS54682.1 - 1.3e-05 25.1 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AAS54682.1 - 3.7e-05 23.1 0.0 0.00011 21.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 AAS54682.1 - 0.0043 17.4 0.1 0.023 15.1 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain FmrO PF07091.6 AAS54682.1 - 0.007 15.3 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_25 PF13649.1 AAS54682.1 - 0.029 14.7 0.0 0.084 13.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 AAS54682.1 - 0.033 14.6 0.1 0.43 11.1 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain CMAS PF02353.15 AAS54682.1 - 0.046 12.7 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 AAS54682.1 - 0.046 13.3 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 AAS54682.1 - 0.071 12.2 0.0 0.18 10.8 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ribosomal_L10 PF00466.15 AAS54683.1 - 5e-10 39.2 0.0 8.2e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 NOGCT PF08155.6 AAS54684.1 - 5.9e-28 96.3 0.5 1.5e-27 95.0 0.3 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 AAS54684.1 - 5.4e-27 93.4 0.4 1.3e-26 92.1 0.3 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 AAS54684.1 - 2.4e-16 59.7 0.0 1.5e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AAS54684.1 - 3.1e-08 33.0 0.0 6.7e-08 31.9 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 AAS54684.1 - 7e-05 22.0 0.3 0.00014 21.1 0.2 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AAS54684.1 - 0.0055 17.2 0.0 0.015 15.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 AAS54684.1 - 0.014 15.2 0.1 10 5.9 0.0 3.1 2 1 1 3 3 3 0 Dynamin family Myb_DNA-bind_4 PF13837.1 AAS54684.1 - 0.037 14.1 3.6 0.094 12.8 1.0 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain AAA_18 PF13238.1 AAS54684.1 - 0.082 13.2 0.7 7.6 6.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain Cyc-maltodext_C PF10438.4 AAS54684.1 - 0.11 12.5 0.4 20 5.3 0.0 2.7 2 0 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain MFS_1 PF07690.11 AAS54685.1 - 2.5e-44 151.4 32.1 3.9e-44 150.8 22.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AAS54685.1 - 1.7e-17 63.1 25.0 1.3e-16 60.2 0.9 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter Pyr_redox_2 PF07992.9 AAS54686.1 - 4.7e-43 147.4 0.0 1e-42 146.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 AAS54686.1 - 9.1e-35 119.0 0.6 4.1e-34 116.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 AAS54686.1 - 8.9e-19 67.6 5.5 1.9e-18 66.6 0.3 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AAS54686.1 - 8.7e-12 45.5 0.1 2.4e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AAS54686.1 - 2e-06 27.1 0.2 1.3e-05 24.5 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AAS54686.1 - 3.1e-06 25.9 3.2 0.14 10.6 0.0 3.1 2 1 1 3 3 3 3 HI0933-like protein AlaDh_PNT_C PF01262.16 AAS54686.1 - 1.5e-05 24.6 0.4 0.0015 18.1 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 AAS54686.1 - 0.00014 20.9 0.0 0.00031 19.7 0.0 1.5 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 AAS54686.1 - 0.00021 20.2 0.0 0.00039 19.3 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.19 AAS54686.1 - 0.0009 18.2 3.9 0.0023 16.9 0.8 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 AAS54686.1 - 0.079 13.2 0.1 7.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 AAS54686.1 - 0.19 10.8 1.3 6 5.9 0.0 2.9 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 AAS54686.1 - 0.28 10.8 0.0 0.28 10.8 0.0 2.6 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 AAS54686.1 - 0.79 8.4 8.0 0.23 10.2 1.8 2.5 3 0 0 3 3 3 0 FAD binding domain Ribosomal_S6e PF01092.14 AAS54687.1 - 3.4e-63 210.9 1.2 7.2e-63 209.9 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e SRF-TF PF00319.13 AAS54688.1 - 3.6e-23 80.5 0.0 6.9e-23 79.6 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Pox_Ag35 PF03286.9 AAS54688.1 - 0.48 9.9 3.6 0.96 8.9 2.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ceramidase PF05875.7 AAS54689.2 - 2.8e-92 308.5 5.7 3.3e-92 308.3 4.0 1.0 1 0 0 1 1 1 1 Ceramidase Beta_elim_lyase PF01212.16 AAS54690.2 - 4.3e-61 206.5 0.3 5.1e-61 206.3 0.2 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 AAS54690.2 - 0.003 16.5 0.0 0.004 16.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Radical_SAM PF04055.16 AAS54691.1 - 6e-17 62.3 0.3 1.8e-16 60.7 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 AAS54691.1 - 6.8e-12 45.2 0.1 2.1e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AAS54691.1 - 0.073 13.2 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AAS54691.1 - 0.11 12.6 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sec16_C PF12931.2 AAS54692.1 - 1.6e-81 274.1 0.0 2.3e-81 273.6 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.2 AAS54692.1 - 4.5e-70 236.4 30.6 4.5e-70 236.4 21.2 5.0 5 1 0 5 5 5 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.2 AAS54692.1 - 1.3e-15 57.4 0.0 3.3e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region MBA1 PF07961.6 AAS54693.1 - 3.3e-107 356.6 0.0 3.7e-107 356.5 0.0 1.0 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 AAS54693.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Tim44-like domain BRO1 PF03097.13 AAS54694.2 - 1.9e-96 323.1 1.5 1.9e-96 323.1 1.0 2.8 4 0 0 4 4 4 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 AAS54694.2 - 6.5e-49 166.4 16.7 1.2e-48 165.6 11.6 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF1484 PF07363.6 AAS54694.2 - 2.8e-05 24.4 0.2 0.00078 19.7 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1484) MetJ PF01340.15 AAS54694.2 - 0.058 13.1 0.1 1 9.1 0.0 2.8 2 1 0 2 2 2 0 Met Apo-repressor, MetJ ABC2_membrane_3 PF12698.2 AAS54694.2 - 1.5 7.7 3.1 2.8 6.8 2.1 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein tRNA_int_end_N2 PF12928.2 AAS54695.1 - 8e-21 73.2 0.1 1.6e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA-synt_2 PF00152.15 AAS54696.1 - 1.5e-109 365.8 0.0 1.9e-109 365.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 AAS54696.1 - 0.0029 17.2 0.0 0.085 12.4 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) WD40 PF00400.27 AAS54697.1 - 8.8e-31 104.6 17.0 2.7e-07 30.2 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 AAS54697.1 - 1.7e-05 23.2 0.5 0.03 12.4 0.0 3.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 AAS54697.1 - 0.00011 22.0 0.0 0.0074 16.0 0.0 3.2 1 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 AAS54697.1 - 0.025 13.3 0.0 0.066 12.0 0.0 1.6 1 1 1 2 2 2 0 Coatomer WD associated region Cytochrom_D1 PF02239.11 AAS54697.1 - 0.036 12.3 0.4 0.33 9.1 0.1 2.6 2 1 1 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.1 AAS54697.1 - 0.19 12.0 1.4 4.9 7.5 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain Hira PF07569.6 AAS54697.1 - 4.4 6.4 5.0 64 2.6 0.2 3.4 3 1 1 4 4 4 0 TUP1-like enhancer of split UMP1 PF05348.6 AAS54698.1 - 1e-22 80.4 0.0 1.3e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 GYF PF02213.11 AAS54699.2 - 2.1e-17 62.4 0.5 7e-17 60.7 0.4 1.9 1 0 0 1 1 1 1 GYF domain Sec66 PF09802.4 AAS54700.1 - 2.1e-79 265.3 4.0 2.4e-79 265.1 2.8 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3443 PF11925.3 AAS54700.1 - 0.13 10.8 0.1 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) NPL4 PF05021.10 AAS54701.1 - 3e-121 404.3 0.0 4e-121 403.8 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 AAS54701.1 - 5.6e-70 233.7 0.7 8.2e-70 233.1 0.5 1.2 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 AAS54701.1 - 1.7e-06 28.1 0.0 3.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 HSP70 PF00012.15 AAS54702.1 - 7e-183 608.7 4.3 7e-183 608.7 3.0 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 AAS54702.1 - 8.1e-09 34.5 0.1 1.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 AAS54702.1 - 2e-07 30.8 0.9 5.3e-06 26.2 0.0 2.9 2 1 0 2 2 2 1 Cell division protein FtsA Trans_reg_C PF00486.23 AAS54702.1 - 0.025 14.4 0.2 0.54 10.1 0.0 2.8 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal Ketoacyl-synt_C PF02801.17 AAS54702.1 - 0.03 14.1 0.8 0.12 12.2 0.0 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Sulfate_transp PF00916.15 AAS54703.1 - 6.7e-48 163.0 1.4 1.7e-47 161.7 1.0 1.7 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 AAS54703.1 - 2.5e-27 94.3 4.9 7.7e-27 92.7 3.4 1.9 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 AAS54703.1 - 8.6e-15 54.1 0.0 1.5e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 STAS domain CHIPS PF11434.3 AAS54703.1 - 0.01 15.4 0.1 0.031 13.9 0.1 1.7 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS Oxidored-like PF09791.4 AAS54704.1 - 1.8e-26 91.2 1.2 3.6e-26 90.3 0.8 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Pex24p PF06398.6 AAS54705.1 - 3.9e-34 118.0 9.9 5e-34 117.6 6.9 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Rpp20 PF12328.3 AAS54706.1 - 9.5e-20 70.7 0.1 3e-18 65.8 0.1 2.2 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 AAS54706.1 - 1.8e-11 43.4 0.0 2.4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Alba Ureidogly_hydro PF04115.7 AAS54708.1 - 2e-41 141.1 0.0 2.3e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase PDH PF02153.12 AAS54709.2 - 1.4e-09 37.2 0.0 6e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Prephenate dehydrogenase F420_oxidored PF03807.12 AAS54709.2 - 8.1e-08 32.5 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 AAS54709.2 - 1.4e-07 31.5 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 AAS54709.2 - 4.1e-06 26.0 0.0 8e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 AAS54709.2 - 4.7e-06 26.1 0.1 1.1e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 AAS54709.2 - 1.5e-05 24.7 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 AAS54709.2 - 0.015 15.4 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 AAS54709.2 - 0.015 15.2 0.0 0.04 13.9 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Rossmann-like PF10727.4 AAS54709.2 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 AAS54709.2 - 0.13 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Arf PF00025.16 AAS54711.2 - 1.1e-74 249.4 0.0 1.2e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 AAS54711.2 - 2.5e-11 43.2 0.0 2.9e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 AAS54711.2 - 2.5e-11 43.1 0.0 3.2e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 AAS54711.2 - 1.2e-10 40.9 0.0 1.5e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 AAS54711.2 - 4.7e-09 35.4 0.3 1.2e-05 24.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 AAS54711.2 - 1.3e-08 35.3 0.0 2.1e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 AAS54711.2 - 4e-05 23.1 0.1 0.00063 19.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AAS54711.2 - 0.00037 20.4 0.0 0.00056 19.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 AAS54711.2 - 0.00039 19.3 0.3 0.037 12.8 0.1 2.8 2 1 0 2 2 2 1 ArgK protein ABC_tran PF00005.22 AAS54711.2 - 0.0032 17.7 0.2 0.0093 16.2 0.2 1.7 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.7 AAS54711.2 - 0.026 14.2 0.2 5.6 6.5 0.1 2.1 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 AAS54711.2 - 0.052 12.9 0.4 4.4 6.6 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 AAS54711.2 - 0.15 11.4 0.4 0.54 9.6 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC1 PF03109.11 AAS54712.2 - 1.5e-21 76.5 0.0 2.6e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family GDPD PF03009.12 AAS54713.2 - 6e-76 255.3 0.0 1e-75 254.5 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SPX PF03105.14 AAS54713.2 - 9.3e-31 107.6 2.6 9.3e-31 107.6 1.8 3.2 4 1 0 4 4 4 1 SPX domain Ank_2 PF12796.2 AAS54713.2 - 2.7e-24 85.3 0.0 1.3e-13 51.1 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AAS54713.2 - 4.9e-20 71.5 0.5 2.4e-07 31.0 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 AAS54713.2 - 1e-18 66.1 3.5 0.0008 19.1 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 AAS54713.2 - 1.7e-15 56.6 0.7 0.0003 20.9 0.0 6.0 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AAS54713.2 - 6.3e-13 47.5 3.6 1.1 9.7 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Arginase PF00491.16 AAS54715.1 - 3.4e-74 249.6 0.1 5e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 Arginase family PEX11 PF05648.9 AAS54716.2 - 2.1e-07 30.4 1.9 0.0019 17.4 0.1 2.9 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) 2-Hacid_dh_C PF02826.14 AAS54717.1 - 1.6e-38 131.6 0.0 3.1e-38 130.7 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AAS54717.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AAS54717.1 - 0.034 14.0 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 AAS54717.1 - 0.19 11.1 0.7 0.39 10.1 0.4 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TFIIA PF03153.8 AAS54718.2 - 6.2e-56 190.9 11.1 6.2e-32 111.9 5.5 2.0 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.4 AAS54718.2 - 1.4 7.5 6.8 1.8 7.2 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Kinetocho_Slk19 PF12709.2 AAS54719.2 - 4e-30 103.7 17.2 4e-30 103.7 11.9 8.3 2 1 6 9 9 9 1 Central kinetochore-associated DUF869 PF05911.6 AAS54719.2 - 2.1e-06 26.2 22.5 2.1e-06 26.2 15.6 3.1 2 1 1 3 3 3 2 Plant protein of unknown function (DUF869) AAA_13 PF13166.1 AAS54719.2 - 0.0048 15.4 60.6 0.0082 14.6 2.9 4.1 2 1 2 4 4 4 3 AAA domain Atg14 PF10186.4 AAS54719.2 - 0.0064 15.4 18.4 0.0064 15.4 12.8 5.4 3 1 2 5 5 5 1 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 AAS54719.2 - 0.0083 15.9 24.5 0.0083 15.9 17.0 5.1 2 1 3 5 5 5 3 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 AAS54719.2 - 1.9 7.5 23.6 0.064 12.4 1.9 3.9 2 1 2 5 5 5 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 AAS54719.2 - 2.5 7.8 98.5 0.015 15.0 12.8 6.4 3 1 4 7 7 7 0 TPR/MLP1/MLP2-like protein RhoGAP PF00620.22 AAS54720.2 - 2.3e-33 114.9 0.0 4.8e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 AAS54720.2 - 1.7e-05 24.9 0.5 5.2e-05 23.3 0.1 2.1 2 0 0 2 2 2 1 PH domain DUF1708 PF08101.6 AAS54720.2 - 0.00013 20.9 0.0 0.00021 20.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) PX PF00787.19 AAS54720.2 - 0.00019 21.1 0.1 0.00049 19.8 0.0 1.7 1 0 0 1 1 1 1 PX domain Hemocyanin_N PF03722.9 AAS54720.2 - 0.19 11.8 0.1 0.61 10.2 0.0 1.8 1 0 0 1 1 1 0 Hemocyanin, all-alpha domain COMP PF11598.3 AAS54720.2 - 0.2 11.7 1.4 0.43 10.6 1.0 1.5 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Radical_SAM PF04055.16 AAS54721.1 - 5.5e-16 59.1 0.0 2e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily BolA PF01722.13 AAS54722.1 - 1.9e-17 62.9 0.0 2.2e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.13 AAS54723.1 - 6.2e-63 212.5 0.1 7.4e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) tRNA-synt_His PF13393.1 AAS54724.1 - 0.095 11.7 1.7 0.39 9.7 0.2 2.0 1 1 1 2 2 2 0 Histidyl-tRNA synthetase MFS_1 PF07690.11 AAS54725.2 - 8.9e-18 64.1 21.7 1.1e-17 63.7 15.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 AAS54725.2 - 3.4e-05 23.5 1.5 9.2e-05 22.1 1.0 1.8 1 0 0 1 1 1 1 MFS_1 like family COX2-transmemb PF09125.5 AAS54725.2 - 5.1 6.7 6.1 2.8 7.5 0.4 3.1 3 1 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane SMC_N PF02463.14 AAS54726.1 - 3.2e-65 219.4 25.2 1.6e-35 122.3 3.6 4.4 3 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AAS54726.1 - 9.9e-20 70.7 2.1 3.7e-19 68.8 0.1 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AAS54726.1 - 7.1e-10 39.3 28.3 2e-06 28.0 0.2 4.7 2 2 2 4 4 4 2 AAA domain AAA_23 PF13476.1 AAS54726.1 - 0.00019 21.8 44.5 0.00019 21.8 30.9 6.6 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 AAS54726.1 - 0.00051 19.5 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.2 AAS54726.1 - 0.036 13.3 105.9 0.021 14.1 10.9 6.8 2 2 3 6 6 6 0 Mechanosensitive ion channel porin domain Rhabdo_glycop PF00974.13 AAS54726.1 - 0.11 10.6 0.7 0.21 9.7 0.0 1.7 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein Reo_sigmaC PF04582.7 AAS54726.1 - 0.25 10.4 35.3 0.39 9.8 5.6 5.9 2 2 4 6 6 6 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 AAS54726.1 - 0.89 9.8 0.0 0.89 9.8 0.0 5.9 3 2 0 3 3 3 0 ABC transporter FAD_binding_1 PF00667.15 AAS54727.1 - 5.7e-65 218.8 0.0 1.1e-64 217.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 AAS54727.1 - 2.4e-08 34.4 0.0 8.3e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AAS54727.1 - 0.12 12.5 0.0 0.71 10.0 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Peptidase_M56 PF05569.6 AAS54727.1 - 0.14 11.1 0.0 12 4.7 0.0 2.5 3 0 0 3 3 3 0 BlaR1 peptidase M56 LMSTEN PF07988.7 AAS54728.2 - 0.025 13.8 0.4 0.053 12.8 0.3 1.5 1 0 0 1 1 1 0 LMSTEN motif HEAT PF02985.17 AAS54728.2 - 0.045 13.8 0.3 0.36 11.0 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat BAG PF02179.11 AAS54729.1 - 1.1e-16 60.6 3.6 1.8e-16 60.0 2.5 1.3 1 0 0 1 1 1 1 BAG domain DUF3090 PF11290.3 AAS54729.1 - 0.096 12.1 0.1 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) Asp PF00026.18 AAS54730.2 - 1.5e-58 198.5 0.0 1.8e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AAS54730.2 - 8.9e-09 35.5 0.0 3.3e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal RVP PF00077.15 AAS54730.2 - 0.0082 16.0 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 AAS54730.2 - 0.021 15.3 0.1 8.4 6.9 0.0 3.4 3 0 0 3 3 3 0 Aspartyl protease Lum_binding PF00677.12 AAS54731.1 - 1.1e-46 156.5 0.2 1e-23 82.9 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain EKR PF10371.4 AAS54731.1 - 0.082 12.4 0.0 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function WD40 PF00400.27 AAS54732.1 - 5.8e-17 60.8 4.5 7.5e-05 22.4 0.1 7.6 8 0 0 8 8 8 3 WD domain, G-beta repeat PQQ_3 PF13570.1 AAS54732.1 - 0.0087 16.3 0.4 26 5.2 0.0 4.5 4 0 0 4 4 4 1 PQQ-like domain Cut8_C PF08559.5 AAS54733.2 - 1.4e-48 164.3 1.5 2e-48 163.8 1.1 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 AAS54733.2 - 3.1e-12 46.0 3.4 5.3e-12 45.3 2.4 1.4 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 AAS54733.2 - 0.012 15.6 0.3 0.024 14.6 0.2 1.6 1 0 0 1 1 1 0 Cut8 proteasome-binding domain ApbE PF02424.10 AAS54733.2 - 0.036 13.3 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 ApbE family NRN1 PF15056.1 AAS54733.2 - 0.08 12.9 0.0 14 5.7 0.0 2.4 1 1 1 2 2 2 0 Neuritin protein family SLS PF14611.1 AAS54733.2 - 0.37 10.1 1.6 0.31 10.4 0.2 1.4 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator Phytochelatin PF05023.9 AAS54734.1 - 0.056 12.4 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Phytochelatin synthase Pkr1 PF08636.5 AAS54735.1 - 0.15 12.1 5.2 0.27 11.3 3.6 1.3 1 0 0 1 1 1 0 ER protein Pkr1 Sedlin_N PF04628.8 AAS54736.1 - 2.4e-50 169.8 0.0 2.9e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 AAS54736.1 - 5.5e-06 26.1 0.2 1e-05 25.3 0.0 1.5 2 0 0 2 2 2 1 Sybindin-like family MIS13 PF08202.6 AAS54737.1 - 1e-61 208.6 3.5 1.6e-61 208.0 2.4 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Med22 PF06179.7 AAS54738.1 - 1.9e-24 85.7 0.0 2.1e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex dUTPase PF00692.14 AAS54739.1 - 2.6e-40 136.8 0.0 3e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 dUTPase DUF3086 PF11285.3 AAS54739.1 - 0.17 10.6 0.1 0.22 10.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Acetyltransf_9 PF13527.1 AAS54740.2 - 0.00043 20.1 0.1 0.0024 17.7 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AAS54740.2 - 0.0015 18.6 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AAS54740.2 - 0.017 15.1 0.1 0.068 13.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family FR47 PF08445.5 AAS54740.2 - 0.022 14.4 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein YcfA PF07927.7 AAS54740.2 - 0.11 12.4 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 YcfA-like protein Peptidase_M16 PF00675.15 AAS54741.2 - 1.8e-31 108.9 0.3 5.8e-31 107.2 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AAS54741.2 - 2e-12 47.2 0.5 3.5e-06 26.8 0.0 3.8 4 0 0 4 4 4 3 Peptidase M16 inactive domain Rrp15p PF07890.7 AAS54742.1 - 1.1e-33 116.0 13.9 1.1e-33 116.0 9.6 2.1 2 1 0 2 2 2 1 Rrp15p Snurportin1 PF11538.3 AAS54742.1 - 0.031 14.0 0.8 0.067 12.9 0.0 2.0 2 0 0 2 2 2 0 Snurportin1 CytochromB561_N PF09786.4 AAS54742.1 - 0.3 9.4 8.0 0.36 9.2 5.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Kinesin PF00225.18 AAS54743.1 - 6.1e-102 340.7 2.3 6.1e-102 340.7 1.6 1.8 2 0 0 2 2 2 1 Kinesin motor domain Acyltransferase PF01553.16 AAS54744.1 - 7.3e-14 51.3 0.0 1.3e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Rhabdo_M1 PF03342.8 AAS54744.1 - 0.057 12.5 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) DAGK_cat PF00781.19 AAS54746.1 - 5.2e-25 87.3 0.0 1.1e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ras PF00071.17 AAS54747.1 - 3.8e-55 185.6 0.2 4.4e-55 185.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS54747.1 - 4.4e-21 75.5 0.0 7e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AAS54747.1 - 5e-15 55.1 0.4 6.3e-15 54.8 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AAS54747.1 - 1.6e-06 27.4 0.1 2e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AAS54747.1 - 6.5e-06 26.0 0.0 9.6e-06 25.5 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AAS54747.1 - 9.2e-06 25.2 0.0 6.2e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AAS54747.1 - 0.00015 21.0 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 AAS54747.1 - 0.00074 19.2 0.4 0.00091 18.9 0.3 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 AAS54747.1 - 0.0028 17.7 0.0 0.0075 16.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 AAS54747.1 - 0.0049 16.0 0.0 0.014 14.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 AAS54747.1 - 0.03 13.8 0.1 0.055 13.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 AAS54747.1 - 0.032 13.7 0.0 0.067 12.6 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 AAS54747.1 - 0.041 13.8 0.0 0.079 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 AAS54747.1 - 0.055 13.1 0.1 0.44 10.2 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 AAS54747.1 - 0.055 12.9 0.1 6 6.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 AAS54747.1 - 0.092 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TMA7 PF09072.5 AAS54748.1 - 1.9e-25 89.0 15.9 2.1e-25 88.9 11.0 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 tRNA-synt_1c PF00749.16 AAS54749.1 - 5.2e-113 376.8 0.0 7.7e-113 376.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 AAS54749.1 - 4.1e-57 192.2 1.7 6.7e-57 191.5 1.2 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 AAS54749.1 - 7.4e-33 113.6 0.0 7.2e-32 110.4 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 AAS54749.1 - 9.5e-24 83.9 3.6 1.9e-23 82.9 2.5 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Red1 PF07964.6 AAS54750.2 - 4.2e-289 960.6 0.1 4.8e-289 960.4 0.1 1.0 1 0 0 1 1 1 1 Rec10 / Red1 Ribosomal_S28e PF01200.13 AAS54751.1 - 7.4e-34 115.3 2.9 8e-34 115.2 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e S_layer_C PF05124.7 AAS54751.1 - 0.14 11.8 0.1 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region PIN_4 PF13638.1 AAS54752.1 - 7.3e-31 107.0 0.1 2.1e-30 105.5 0.1 1.8 1 0 0 1 1 1 1 PIN domain XLF PF09302.6 AAS54753.1 - 2.3e-16 60.0 0.5 5.1e-15 55.6 0.3 2.1 1 1 0 1 1 1 1 XLF (XRCC4-like factor) DinB_2 PF12867.2 AAS54753.1 - 0.15 12.4 0.2 0.51 10.6 0.1 1.9 2 0 0 2 2 2 0 DinB superfamily RHD3 PF05879.7 AAS54754.1 - 1.3e-229 763.9 10.7 1.7e-229 763.6 7.4 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 AAS54754.1 - 1.2e-07 31.1 0.6 3.1e-07 29.7 0.4 1.8 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 AAS54754.1 - 8.9e-06 25.6 0.1 2.6e-05 24.1 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AAS54754.1 - 2e-05 24.4 0.0 5.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 AAS54754.1 - 0.00014 22.3 0.1 0.00051 20.5 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 AAS54754.1 - 0.0014 17.6 1.2 0.0029 16.6 0.1 2.0 2 0 0 2 2 2 1 Septin AAA_28 PF13521.1 AAS54754.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AAS54754.1 - 0.066 13.3 0.9 1.2 9.3 0.1 3.1 2 2 1 3 3 3 0 AAA domain AAA_29 PF13555.1 AAS54754.1 - 0.096 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF410 PF04190.8 AAS54755.1 - 1.1e-58 198.8 0.0 1.3e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) NUDIX PF00293.23 AAS54756.1 - 6.3e-18 64.7 0.1 7.2e-18 64.5 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain Longin PF13774.1 AAS54757.2 - 3.4e-20 71.3 0.2 5.2e-20 70.7 0.2 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 AAS54757.2 - 1.2e-14 53.7 0.0 2.1e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 AAS54757.2 - 0.0034 17.1 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DcpS PF05652.7 AAS54758.1 - 1.4e-36 125.2 0.0 2.2e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 AAS54758.1 - 5.2e-32 110.5 0.0 1e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF4187 PF13821.1 AAS54759.2 - 3.6e-18 64.9 3.1 6.1e-18 64.1 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 AAS54759.2 - 5e-05 23.0 2.0 0.00011 21.9 1.4 1.6 1 0 0 1 1 1 1 G-patch domain HutD PF05962.6 AAS54759.2 - 0.087 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 HutD Med4 PF10018.4 AAS54760.1 - 1.2e-41 142.2 0.5 5.1e-41 140.1 0.2 2.0 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 TMF_TATA_bd PF12325.3 AAS54760.1 - 0.075 12.7 2.3 0.16 11.6 0.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding MBOAT PF03062.14 AAS54761.2 - 1.5e-60 205.0 8.7 1.5e-60 205.0 6.0 1.9 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF3546 PF12066.3 AAS54761.2 - 0.5 10.4 7.0 2.5 8.1 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3546) Ferrochelatase PF00762.14 AAS54762.1 - 8.4e-90 300.9 0.0 9.7e-90 300.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase NodZ PF05830.6 AAS54762.1 - 0.018 13.6 0.0 0.024 13.2 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) Cnd1 PF12717.2 AAS54763.2 - 3.8e-54 183.2 8.0 3.4e-50 170.3 0.5 4.4 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 AAS54763.2 - 8e-49 165.5 2.6 9.8e-49 165.2 0.3 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 AAS54763.2 - 2.8e-13 49.9 0.1 0.00031 20.9 0.0 5.0 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 AAS54763.2 - 3.8e-11 42.0 2.9 0.25 11.4 0.0 6.4 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 AAS54763.2 - 2.3e-05 24.7 5.9 0.047 14.1 0.0 5.7 7 0 0 7 7 7 1 HEAT-like repeat Cnd3 PF12719.2 AAS54763.2 - 4.2e-05 22.6 3.1 0.0009 18.3 0.5 3.4 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.2 AAS54763.2 - 0.02 14.8 0.5 13 5.8 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DUF2435 PF10363.4 AAS54763.2 - 0.022 14.6 3.7 5.7 6.9 0.0 5.2 5 3 2 7 7 7 0 Protein of unknown function (DUF2435) IncA PF04156.9 AAS54764.1 - 0.00022 20.9 8.2 0.00038 20.1 5.7 1.4 1 0 0 1 1 1 1 IncA protein HALZ PF02183.13 AAS54764.1 - 0.00035 20.2 9.0 1.3 8.7 0.3 4.6 3 1 1 4 4 4 2 Homeobox associated leucine zipper Jnk-SapK_ap_N PF09744.4 AAS54764.1 - 0.0028 17.6 8.8 0.0048 16.9 6.1 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Phage_GP20 PF06810.6 AAS54764.1 - 0.04 13.3 10.5 0.034 13.5 5.2 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 bZIP_1 PF00170.16 AAS54764.1 - 0.065 13.1 7.8 0.47 10.4 1.1 3.2 2 1 1 3 3 3 0 bZIP transcription factor Med28 PF11594.3 AAS54764.1 - 0.1 12.8 0.0 0.1 12.8 0.0 2.4 1 1 1 2 2 2 0 Mediator complex subunit 28 APG6 PF04111.7 AAS54764.1 - 0.18 10.8 13.1 0.046 12.7 4.9 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF641 PF04859.7 AAS54764.1 - 0.19 11.4 6.9 0.37 10.5 1.5 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Spc7 PF08317.6 AAS54764.1 - 0.21 10.1 10.4 0.31 9.6 7.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 AAS54764.1 - 0.29 10.8 10.8 2 8.1 1.6 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.14 AAS54764.1 - 0.36 8.6 3.1 0.49 8.1 2.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 AAS54764.1 - 0.39 9.6 12.3 0.65 8.8 8.5 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tnp_P_element PF12017.3 AAS54764.1 - 0.41 9.8 6.4 0.31 10.2 2.7 1.9 1 1 1 2 2 2 0 Transposase protein TMF_DNA_bd PF12329.3 AAS54764.1 - 0.42 10.4 10.2 6.7 6.5 0.2 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 AAS54764.1 - 0.94 9.3 14.1 12 5.7 8.4 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 AAS54764.1 - 3.1 7.3 8.5 18 4.9 0.3 2.8 1 1 1 2 2 2 0 Septum formation initiator DUF972 PF06156.8 AAS54764.1 - 3.1 8.1 11.7 13 6.1 2.1 3.0 2 1 1 3 3 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 AAS54764.1 - 4.3 7.1 20.0 1.2 8.8 0.2 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF948 PF06103.6 AAS54764.1 - 5.3 6.9 7.6 4.1 7.3 0.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.7 AAS54764.1 - 7.1 6.3 15.6 37 4.0 8.2 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein CBM_21 PF03370.8 AAS54765.2 - 8e-29 99.9 5.4 1.5e-28 99.0 3.7 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit MCM PF00493.18 AAS54766.1 - 2.8e-143 476.7 0.2 3.6e-143 476.3 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AAS54766.1 - 2.7e-18 66.6 0.1 7.3e-18 65.2 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.9 AAS54766.1 - 1.9e-06 27.6 0.0 4.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AAS54766.1 - 2.9e-06 26.5 0.0 0.00055 19.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AAS54766.1 - 0.00045 19.8 0.0 0.0017 17.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Imm19 PF15567.1 AAS54766.1 - 0.0066 16.4 0.0 0.034 14.1 0.0 2.2 3 0 0 3 3 3 1 Immunity protein 19 Sigma54_activat PF00158.21 AAS54766.1 - 0.02 14.3 0.2 1.3 8.4 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 AAS54766.1 - 0.088 13.2 0.3 0.088 13.2 0.2 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 AAS54766.1 - 0.11 12.7 0.1 0.63 10.2 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) LSM PF01423.17 AAS54767.1 - 4.1e-18 64.6 0.3 5.1e-18 64.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain DEAD PF00270.24 AAS54768.1 - 2.8e-36 124.5 0.9 5.8e-36 123.5 0.6 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS54768.1 - 2.2e-22 78.6 0.0 1.4e-11 44.0 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 AAS54768.1 - 0.00011 22.1 1.2 0.001 18.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 AAS54768.1 - 0.017 14.4 0.1 2.2 7.5 0.0 2.6 2 1 0 2 2 2 0 SecA DEAD-like domain CPSF73-100_C PF11718.3 AAS54769.2 - 6.9e-63 211.8 1.9 1.3e-62 211.0 1.3 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 AAS54769.2 - 3.1e-33 114.4 0.0 1.8e-32 111.9 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 AAS54769.2 - 1.3e-15 57.5 0.9 2.4e-15 56.6 0.6 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AAS54769.2 - 4.4e-11 42.7 0.9 2.9e-10 40.0 0.3 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 AAS54769.2 - 2.6e-10 39.9 0.0 5.6e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 AAS54769.2 - 1.2e-05 25.1 0.2 3.2e-05 23.7 0.2 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.13 AAS54770.2 - 1.4e-16 60.2 0.2 3.2e-16 59.0 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS54770.2 - 3.7e-05 23.5 9.1 3.7e-05 23.5 6.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RF-1 PF00472.15 AAS54771.1 - 7.5e-19 67.6 3.9 1.6e-18 66.5 2.7 1.5 1 1 0 1 1 1 1 RF-1 domain DUF1640 PF07798.6 AAS54772.1 - 6.3e-09 36.1 1.7 8.5e-09 35.6 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) AvrPphF-ORF-2 PF09143.5 AAS54772.1 - 0.038 13.6 0.3 0.059 13.0 0.2 1.2 1 0 0 1 1 1 0 AvrPphF-ORF-2 DUF2975 PF11188.3 AAS54772.1 - 0.4 10.4 3.1 8.4 6.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) ECH PF00378.15 AAS54773.1 - 1.5e-13 50.4 0.0 2.4e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family A_deaminase_N PF08451.6 AAS54773.1 - 0.13 12.2 0.1 0.28 11.2 0.1 1.5 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal Methyltransf_16 PF10294.4 AAS54774.1 - 5.9e-12 45.3 0.0 7.4e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 AAS54774.1 - 0.0074 16.8 0.0 0.016 15.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AAS54774.1 - 0.016 14.9 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain WH1 PF00568.18 AAS54775.1 - 7.1e-32 109.4 0.0 1e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 AAS54775.1 - 0.0016 17.9 0.7 0.0035 16.8 0.5 1.6 1 0 0 1 1 1 1 WH2 motif Mor PF08765.6 AAS54775.1 - 0.22 11.3 0.0 0.42 10.4 0.0 1.4 1 0 0 1 1 1 0 Mor transcription activator family GCIP PF13324.1 AAS54776.1 - 4.4e-09 35.9 1.6 1e-08 34.7 1.2 1.5 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting SEN1_N PF12726.2 AAS54776.1 - 0.00022 19.4 0.6 0.00031 18.9 0.4 1.3 1 1 0 1 1 1 1 SEN1 N terminal DASH_Dad3 PF08656.5 AAS54776.1 - 0.066 12.9 4.7 4.7 6.9 0.0 3.8 3 1 0 3 3 3 0 DASH complex subunit Dad3 YkyA PF10368.4 AAS54776.1 - 0.77 9.0 7.0 0.13 11.6 0.7 2.5 2 1 1 3 3 3 0 Putative cell-wall binding lipoprotein Ribosomal_S30 PF04758.9 AAS54777.1 - 2.9e-30 103.7 6.2 3.4e-30 103.5 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Aminotran_5 PF00266.14 AAS54778.1 - 8e-33 113.6 0.0 9.2e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Hus1 PF04005.7 AAS54779.2 - 1.8e-26 92.7 0.0 2.6e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Hus1-like protein GTP_EFTU PF00009.22 AAS54780.1 - 1.8e-47 161.2 0.0 3.6e-47 160.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 AAS54780.1 - 3e-37 126.8 8.4 3e-37 126.8 5.9 1.7 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 AAS54780.1 - 2.6e-19 68.8 0.0 4.7e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AAS54780.1 - 8.2e-07 29.0 0.5 0.023 14.8 0.1 2.8 1 1 1 2 2 2 2 Elongation factor Tu domain 2 Ras PF00071.17 AAS54780.1 - 4.2e-05 22.9 0.2 0.0017 17.7 0.0 2.4 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 AAS54780.1 - 0.0067 15.6 0.0 0.016 14.4 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.1 AAS54780.1 - 0.015 15.1 0.0 0.046 13.5 0.0 1.9 1 0 0 1 1 1 0 Elongation Factor G, domain II NAD_binding_10 PF13460.1 AAS54781.1 - 1.4e-11 44.7 0.0 1.5e-10 41.3 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 AAS54781.1 - 0.00013 20.9 0.0 0.13 11.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 AAS54781.1 - 0.00014 20.6 0.0 0.00039 19.2 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AAS54781.1 - 0.00024 20.6 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 AAS54781.1 - 0.0042 17.0 0.0 0.0093 15.8 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AAS54781.1 - 0.064 12.9 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 KR domain BDHCT PF08072.6 AAS54781.1 - 0.093 12.8 0.7 0.23 11.5 0.5 1.7 1 0 0 1 1 1 0 BDHCT (NUC031) domain IF-2B PF01008.12 AAS54782.1 - 3.2e-77 259.2 0.1 5.6e-77 258.5 0.1 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family ABC_sub_bind PF04392.7 AAS54782.1 - 0.021 13.7 0.1 0.051 12.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter substrate binding protein Arf PF00025.16 AAS54782.1 - 0.074 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family CpXC PF14353.1 AAS54782.1 - 0.09 12.7 0.4 0.24 11.3 0.3 1.7 1 0 0 1 1 1 0 CpXC protein TPR_2 PF07719.12 AAS54783.1 - 4.8e-05 22.9 0.1 0.0012 18.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 AAS54783.1 - 5.8e-05 22.6 0.1 0.0069 16.0 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 AAS54783.1 - 0.00015 21.1 0.0 0.005 16.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 AAS54783.1 - 0.0033 17.7 1.0 0.035 14.4 0.1 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 AAS54783.1 - 0.017 15.0 0.8 0.21 11.5 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 AAS54783.1 - 0.027 15.1 3.0 0.35 11.5 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 AAS54783.1 - 0.074 12.8 0.1 0.62 9.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AAS54783.1 - 0.074 12.9 0.2 0.074 12.9 0.1 2.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat IDEAL PF08858.5 AAS54783.1 - 0.089 12.3 0.1 0.24 10.9 0.1 1.8 1 0 0 1 1 1 0 IDEAL domain Vhr1 PF04001.8 AAS54783.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Transcription factor Vhr1 TPR_14 PF13428.1 AAS54783.1 - 0.77 10.5 0.1 0.77 10.5 0.1 2.8 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 AAS54783.1 - 0.89 9.4 5.6 13 5.7 1.4 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat GTPase_Cys_C PF12631.2 AAS54783.1 - 1.7 9.1 4.0 71 3.9 2.8 3.0 1 1 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Ras PF00071.17 AAS54784.1 - 1.1e-50 171.1 0.0 1.4e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AAS54784.1 - 5.9e-17 62.2 0.0 1.3e-16 61.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AAS54784.1 - 1.8e-11 43.6 0.0 2.4e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 AAS54784.1 - 0.00081 19.5 0.1 0.0054 16.8 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 AAS54784.1 - 0.0011 18.1 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 AAS54784.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit KaiC PF06745.8 AAS54784.1 - 0.02 14.0 0.1 0.031 13.3 0.1 1.2 1 0 0 1 1 1 0 KaiC Pox_A32 PF04665.7 AAS54784.1 - 0.026 13.8 0.1 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 AAS54784.1 - 0.041 14.0 0.2 0.16 12.1 0.1 2.0 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.15 AAS54784.1 - 0.052 12.2 2.7 1.1 7.8 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit AAA_33 PF13671.1 AAS54784.1 - 0.07 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AAS54784.1 - 0.14 11.8 0.1 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATP_sub_h PF10775.4 AAS54785.2 - 8.2e-25 86.3 0.1 1.1e-24 85.9 0.1 1.1 1 0 0 1 1 1 1 ATP synthase complex subunit h zf-AN1 PF01428.11 AAS54786.1 - 8.9e-10 38.2 8.6 1e-09 38.0 5.6 1.4 1 1 0 1 1 1 1 AN1-like Zinc finger Hydrolase_6 PF13344.1 AAS54787.2 - 1.1e-26 92.6 0.0 2.3e-26 91.6 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AAS54787.2 - 7e-24 83.3 0.0 1.7e-23 82.1 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 AAS54787.2 - 7e-10 39.4 0.3 0.00011 22.5 0.0 3.2 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AAS54787.2 - 9.1e-07 29.4 0.0 0.0019 18.6 0.0 2.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase PrpR_N PF06506.6 AAS54787.2 - 0.048 13.0 0.0 0.27 10.6 0.0 2.3 3 0 0 3 3 3 0 Propionate catabolism activator TP_methylase PF00590.15 AAS54788.2 - 1.1e-44 152.6 0.9 2.1e-44 151.7 0.6 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 AAS54788.2 - 4.9e-07 29.9 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 AAS54788.2 - 0.027 13.4 0.0 0.053 12.5 0.0 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.1 AAS54788.2 - 0.046 13.0 0.1 1.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Nro1 PF12753.2 AAS54789.1 - 1.5e-151 504.9 9.3 1.7e-151 504.7 6.4 1.0 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 TPR_19 PF14559.1 AAS54789.1 - 0.002 18.4 0.7 0.042 14.1 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF45 PF01863.12 AAS54789.1 - 0.019 14.7 1.7 0.027 14.2 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF45 DNAJ_related PF12339.3 AAS54789.1 - 0.09 12.6 1.9 0.18 11.6 0.3 2.1 2 0 0 2 2 2 0 DNA-J related protein TRAPP PF04051.11 AAS54790.2 - 2.9e-36 124.2 0.0 3.4e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Lipoprotein_Ltp PF07553.6 AAS54790.2 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein Acyltransferase PF01553.16 AAS54791.2 - 2.1e-09 36.9 0.0 2.7e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase XRN_N PF03159.13 AAS54793.2 - 1.3e-106 355.2 0.1 2.8e-106 354.2 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus PseudoU_synth_2 PF00849.17 AAS54795.1 - 1.3e-26 93.3 0.0 2.2e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase SH3_1 PF00018.23 AAS54796.1 - 2.3e-08 33.3 0.2 6.1e-08 31.9 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AAS54796.1 - 4e-08 32.7 0.1 8.2e-08 31.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AAS54796.1 - 0.0003 20.1 0.3 0.001 18.5 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain Clathrin_lg_ch PF01086.12 AAS54799.1 - 9.5e-43 146.7 6.7 1.1e-42 146.5 4.6 1.0 1 0 0 1 1 1 1 Clathrin light chain PHA_synth_III_E PF09712.5 AAS54799.1 - 0.0076 15.6 2.0 0.0087 15.4 1.4 1.1 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Urm1 PF09138.6 AAS54799.1 - 0.047 13.8 0.1 0.079 13.0 0.1 1.4 1 1 0 1 1 1 0 Urm1 (Ubiquitin related modifier) DUF3507 PF12015.3 AAS54799.1 - 0.12 11.9 0.3 0.17 11.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) 4HB_MCP_1 PF12729.2 AAS54799.1 - 0.61 9.4 4.3 0.71 9.1 2.5 1.4 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction GIDA_assoc_3 PF13932.1 AAS54799.1 - 6.6 6.8 6.6 0.66 10.0 0.8 2.0 2 0 0 2 2 2 0 GidA associated domain 3 Trs65 PF12735.2 AAS54800.1 - 8.7e-50 169.7 2.6 1.5e-49 168.9 1.8 1.4 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 Bot1p PF12298.3 AAS54801.2 - 2.6e-54 183.7 1.7 3.6e-54 183.2 1.2 1.2 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Sad1_UNC PF07738.8 AAS54802.1 - 9.3e-07 28.7 1.4 1.2e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Sds3 PF08598.6 AAS54802.1 - 0.0024 17.4 0.1 0.0045 16.5 0.1 1.6 1 0 0 1 1 1 1 Sds3-like Baculo_PEP_C PF04513.7 AAS54802.1 - 0.035 13.9 5.6 0.11 12.2 2.0 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_61 PF03443.9 AAS54802.1 - 0.06 13.1 2.5 0.43 10.3 0.0 2.5 3 0 0 3 3 3 0 Glycosyl hydrolase family 61 FlaC_arch PF05377.6 AAS54802.1 - 0.46 10.4 6.8 0.55 10.1 0.3 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF342 PF03961.8 AAS54802.1 - 0.67 8.2 3.2 1.1 7.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) UPF0118 PF01594.11 AAS54802.1 - 0.91 8.4 2.9 1.3 7.9 0.1 2.1 1 1 2 3 3 3 0 Domain of unknown function DUF20 YlqD PF11068.3 AAS54802.1 - 3.1 7.8 8.6 21 5.1 5.9 2.3 1 1 0 1 1 1 0 YlqD protein Cpn60_TCP1 PF00118.19 AAS54804.1 - 2.9e-151 504.4 1.2 3.3e-151 504.2 0.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mad3_BUB1_I PF08311.7 AAS54805.2 - 7e-42 142.1 0.8 7e-42 142.1 0.5 1.8 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.6 AAS54805.2 - 5.2e-32 109.5 0.1 3.8e-31 106.7 0.0 2.4 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.20 AAS54805.2 - 9.3e-21 74.1 0.0 1.7e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS54805.2 - 0.00015 20.9 0.0 0.00029 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AAS54805.2 - 0.015 14.2 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pox_A_type_inc PF04508.7 AAS54805.2 - 0.064 13.0 3.1 1.1 9.1 0.1 3.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat VTC PF09359.5 AAS54806.1 - 2.1e-103 345.2 0.1 3e-103 344.7 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 AAS54806.1 - 4.2e-21 75.9 9.7 1.5e-09 38.0 0.3 3.3 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 AAS54806.1 - 1.1e-08 35.2 2.3 1.9e-08 34.4 1.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LXG PF04740.7 AAS54806.1 - 0.048 13.4 0.4 0.048 13.4 0.3 2.3 2 1 1 3 3 3 0 LXG domain of WXG superfamily RNA_pol_Rpb4 PF03874.11 AAS54807.1 - 1.2e-31 109.1 2.5 1.4e-31 108.8 1.7 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Glyco_hydro_16 PF00722.16 AAS54808.1 - 1.3e-45 154.9 0.6 1.3e-45 154.9 0.4 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 DUF1080 PF06439.6 AAS54808.1 - 0.029 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) AA_permease PF00324.16 AAS54809.1 - 1.4e-129 432.5 34.1 1.7e-129 432.2 23.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AAS54809.1 - 2.4e-32 112.0 38.6 2.9e-32 111.7 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease EIF_2_alpha PF07541.7 AAS54810.2 - 2e-42 143.4 1.5 4.7e-42 142.2 0.3 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 AAS54810.2 - 3.1e-15 55.9 1.7 6.2e-15 55.0 1.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Viral_env_E26 PF11050.3 AAS54810.2 - 0.049 12.8 0.2 0.088 11.9 0.2 1.4 1 0 0 1 1 1 0 Virus envelope protein E26 EXOSC1 PF10447.4 AAS54810.2 - 0.05 13.5 0.3 0.16 11.9 0.2 1.9 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Memo PF01875.12 AAS54811.2 - 3.7e-85 285.1 0.0 4.3e-85 284.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein ATP-sulfurylase PF01747.12 AAS54812.1 - 5.4e-83 277.5 0.0 7e-83 277.1 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 AAS54812.1 - 2.9e-53 179.5 0.0 4.4e-53 178.9 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Biotin_lipoyl PF00364.17 AAS54813.2 - 1.3e-18 66.3 0.7 3e-18 65.2 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 AAS54813.2 - 1.3e-05 24.7 0.0 3.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain FGGY_N PF00370.16 AAS54814.2 - 3.1e-19 69.2 0.0 2.8e-13 49.7 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 AAS54814.2 - 9.8e-19 67.7 0.0 2.5e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain SPC12 PF06645.8 AAS54815.1 - 6.9e-21 73.8 0.0 8.1e-21 73.6 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) NrfD PF03916.9 AAS54815.1 - 0.052 12.9 0.4 0.061 12.7 0.3 1.0 1 0 0 1 1 1 0 Polysulphide reductase, NrfD Candida_ALS_N PF11766.3 AAS54817.3 - 2.1e-74 249.5 0.7 2.1e-74 249.5 0.5 2.5 2 0 0 2 2 2 1 Cell-wall agglutinin N-terminal ligand-sugar binding NAD_binding_6 PF08030.7 AAS54818.1 - 1.2e-18 67.4 0.0 2.1e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 AAS54818.1 - 3.9e-18 65.2 0.0 6.8e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 AAS54818.1 - 2.1e-13 50.4 9.8 2.1e-13 50.4 6.8 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Oxidored_FMN PF00724.15 AAS54819.1 - 8.9e-114 380.0 0.0 1e-113 379.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aminotran_4 PF01063.14 AAS54820.1 - 8.8e-23 80.9 0.0 1.6e-22 80.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class IV Kdo PF06293.9 AAS54821.1 - 2.6e-08 33.1 0.0 4.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AAS54821.1 - 0.0017 18.1 0.0 0.42 10.2 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 AAS54821.1 - 0.0025 17.0 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain tRNA-synt_1g PF09334.6 AAS54822.1 - 6.7e-148 492.5 0.2 8.9e-148 492.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.5 AAS54822.1 - 3.4e-52 175.9 0.0 1.1e-51 174.3 0.0 1.9 1 0 0 1 1 1 1 MetRS-N binding domain tRNA-synt_1 PF00133.17 AAS54822.1 - 9.1e-10 37.1 0.2 0.00086 17.4 0.2 2.8 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 AAS54822.1 - 0.027 13.5 0.0 0.081 12.0 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 AAS54822.1 - 0.031 14.0 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Med27 PF11571.3 AAS54822.1 - 0.05 13.7 1.2 23 5.1 0.0 3.3 3 0 0 3 3 3 0 Mediator complex subunit 27 DEAD PF00270.24 AAS54823.2 - 1.9e-44 151.1 0.8 8e-44 149.1 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AAS54823.2 - 3.1e-22 78.2 0.0 6.2e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 AAS54823.2 - 1.2e-20 72.8 0.1 2.5e-20 71.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) SecA_DEAD PF07517.9 AAS54823.2 - 0.0029 16.9 0.0 0.0078 15.5 0.0 1.7 1 1 0 1 1 1 1 SecA DEAD-like domain ResIII PF04851.10 AAS54823.2 - 0.011 15.6 0.0 0.029 14.2 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AAS54823.2 - 0.05 13.7 0.9 0.33 11.1 0.7 2.4 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.20 AAS54824.1 - 3.2e-52 177.2 0.1 1.8e-51 174.8 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AAS54824.1 - 1e-22 80.4 0.1 2.2e-19 69.5 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AAS54824.1 - 0.0015 17.5 0.0 0.01 14.8 0.0 2.0 1 1 0 1 1 1 1 Kinase-like GTP_cyclohydroI PF01227.17 AAS54825.1 - 5.5e-76 253.8 0.2 6.6e-76 253.5 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 AAS54825.1 - 7.8e-05 22.5 0.0 0.00027 20.8 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein DnaJ_CXXCXGXG PF00684.14 AAS54826.1 - 6e-05 23.0 9.5 0.003 17.5 0.7 2.2 2 0 0 2 2 2 2 DnaJ central domain OrfB_Zn_ribbon PF07282.6 AAS54826.1 - 2 8.1 4.9 0.87 9.2 0.8 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Got1 PF04178.7 AAS54827.1 - 7.8e-19 67.9 13.8 9e-19 67.7 9.6 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 AAS54827.1 - 0.00039 19.4 5.6 0.00049 19.1 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF973) DUF3951 PF13131.1 AAS54827.1 - 0.026 14.3 0.2 0.026 14.3 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3951) DUF4401 PF14351.1 AAS54827.1 - 1.5 7.7 16.0 7.4 5.4 11.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) Spc97_Spc98 PF04130.8 AAS54828.2 - 4.9e-80 269.3 15.5 4.9e-80 269.3 10.7 1.6 2 0 0 2 2 2 1 Spc97 / Spc98 family DUF3402 PF11882.3 AAS54829.1 - 9e-101 337.8 7.3 2.4e-99 333.1 5.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 AAS54829.1 - 3.2e-76 255.9 0.6 5.6e-76 255.2 0.4 1.4 1 0 0 1 1 1 1 N1221-like protein IBV_3A PF03617.8 AAS54829.1 - 0.028 14.1 0.5 0.29 10.9 0.0 2.5 2 0 0 2 2 2 0 IBV 3A protein AD PF09793.4 AAS54830.1 - 3.2e-19 68.5 0.0 4.8e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain DUF3748 PF12566.3 AAS54830.1 - 0.035 14.0 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) DAP_epimerase PF01678.14 AAS54830.1 - 0.062 13.2 0.1 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Diaminopimelate epimerase DSPc PF00782.15 AAS54831.1 - 5.8e-11 42.0 0.0 1.3e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 AAS54831.1 - 0.049 13.8 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 AAS54831.1 - 0.079 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 AAS54831.1 - 0.084 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase AAA_17 PF13207.1 AAS54832.2 - 7.2e-06 26.8 0.1 3e-05 24.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AAS54832.2 - 8.4e-06 26.1 0.0 3.9e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AAS54832.2 - 0.0086 15.9 0.0 0.033 14.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 AAS54832.2 - 0.047 13.3 0.0 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PRK PF00485.13 AAS54832.2 - 0.055 13.0 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 AAS54832.2 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF59 PF01883.14 AAS54833.1 - 9.2e-06 25.5 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 TEX13 PF15186.1 AAS54833.1 - 0.0071 15.9 0.1 0.017 14.7 0.1 1.6 1 0 0 1 1 1 1 Testis-expressed sequence 13 protein family CDP-OH_P_transf PF01066.16 AAS54834.1 - 7.6e-18 64.6 1.6 7.6e-18 64.6 1.1 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4118 PF13493.1 AAS54834.1 - 0.0081 16.3 1.0 0.0081 16.3 0.7 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4118) Tom22 PF04281.8 AAS54835.1 - 2e-51 173.1 1.6 2.2e-51 172.9 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4407 PF14362.1 AAS54835.1 - 0.077 11.9 0.4 0.098 11.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GNAT_acetyltr_2 PF13718.1 AAS54836.2 - 4e-80 267.7 0.0 7.6e-80 266.8 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 AAS54836.2 - 1.4e-64 216.9 0.0 7.9e-64 214.5 0.0 2.3 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 AAS54836.2 - 6.6e-40 134.7 0.1 2.8e-39 132.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 AAS54836.2 - 4.7e-37 126.1 0.6 1.5e-36 124.5 0.4 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 AAS54836.2 - 0.0094 16.1 0.0 0.033 14.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DEAD PF00270.24 AAS54836.2 - 0.057 12.9 0.0 0.19 11.2 0.0 1.9 1 0 0 1 1 1 0 DEAD/DEAH box helicase NDT80_PhoG PF05224.7 AAS54837.1 - 6.4e-69 231.6 0.8 1.7e-68 230.3 0.6 1.7 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family HIM1 PF08732.5 AAS54838.2 - 2.2e-194 645.6 0.1 2.5e-194 645.4 0.0 1.0 1 0 0 1 1 1 1 HIM1 CENP-O PF09496.5 AAS54839.2 - 5.2e-23 81.0 0.0 1.4e-22 79.7 0.0 1.8 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Prefoldin_2 PF01920.15 AAS54839.2 - 0.076 12.7 1.4 0.97 9.2 0.7 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF4404 PF14357.1 AAS54839.2 - 0.12 12.7 2.4 0.27 11.6 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) IncA PF04156.9 AAS54839.2 - 0.2 11.2 2.7 0.34 10.4 1.9 1.4 1 0 0 1 1 1 0 IncA protein Golgin_A5 PF09787.4 AAS54839.2 - 0.22 10.0 4.8 0.3 9.5 3.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2360 PF10152.4 AAS54839.2 - 0.27 11.4 3.7 0.4 10.9 1.3 1.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Scs3p PF10261.4 AAS54840.2 - 4.2e-40 137.2 14.6 2.9e-39 134.5 10.1 2.2 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Yip1 PF04893.12 AAS54840.2 - 0.045 13.2 9.0 1.7 8.1 2.8 2.2 2 0 0 2 2 2 0 Yip1 domain PAP2 PF01569.16 AAS54840.2 - 0.5 10.0 9.2 0.096 12.3 3.9 1.7 2 1 0 2 2 2 0 PAP2 superfamily PepSY_TM PF03929.11 AAS54840.2 - 9.7 6.8 11.5 1.4 9.4 0.1 3.3 2 0 0 2 2 2 0 PepSY-associated TM helix Prenyltrans_2 PF13249.1 AAS54841.2 - 9.7e-31 106.5 0.3 2.2e-15 57.0 0.0 5.2 3 2 3 6 6 6 5 Prenyltransferase-like Prenyltrans PF00432.16 AAS54841.2 - 2e-25 88.0 0.3 7.7e-09 34.9 0.0 4.0 3 0 0 3 3 3 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 AAS54841.2 - 8.8e-24 83.6 0.0 1.9e-11 43.9 0.1 5.8 2 2 5 7 7 7 4 Prenyltransferase-like Pec_lyase PF09492.5 AAS54841.2 - 0.0026 16.9 0.1 0.83 8.7 0.0 3.1 3 1 1 4 4 4 2 Pectic acid lyase A2M_comp PF07678.9 AAS54841.2 - 0.1 11.8 0.0 0.59 9.3 0.0 2.1 1 1 1 2 2 2 0 A-macroglobulin complement component Ubiq-assoc PF09145.5 AAS54842.1 - 1.6e-21 75.8 0.8 3.4e-21 74.8 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin-associated TPR_12 PF13424.1 AAS54842.1 - 3.1e-06 27.0 0.7 0.0042 16.9 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.26 AAS54842.1 - 7.9e-06 25.5 0.0 0.00031 20.4 0.0 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 AAS54842.1 - 0.002 17.7 1.4 0.38 10.4 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 AAS54842.1 - 0.0045 16.5 0.3 10 5.9 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 AAS54842.1 - 0.006 16.4 1.4 1.2 9.2 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 AAS54842.1 - 0.13 12.1 3.9 3.6 7.5 0.4 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 AAS54842.1 - 0.17 12.3 1.2 1.9 9.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4407 PF14362.1 AAS54842.1 - 0.26 10.2 2.1 0.43 9.4 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_8 PF13181.1 AAS54842.1 - 0.39 10.6 3.5 1.5 8.8 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DivIC PF04977.10 AAS54843.1 - 0.00047 19.5 0.4 0.00088 18.7 0.3 1.4 1 0 0 1 1 1 1 Septum formation initiator Glyco_trans_1_2 PF13524.1 AAS54843.1 - 0.013 15.7 0.6 0.021 15.0 0.4 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Tad PF13400.1 AAS54843.1 - 0.094 12.7 0.3 0.25 11.3 0.2 1.7 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like DUF4400 PF14348.1 AAS54843.1 - 4.4 6.6 7.1 10 5.4 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Nop10p PF04135.7 AAS54844.1 - 2.2e-21 75.3 0.2 3.4e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DASH_Dad4 PF08650.5 AAS54845.1 - 1.8e-38 130.2 0.5 2e-38 130.1 0.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 FAM117 PF15388.1 AAS54845.1 - 0.021 14.0 0.2 0.023 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein Family FAM117 DivIC PF04977.10 AAS54845.1 - 0.038 13.4 0.1 0.054 12.9 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator Syntaxin_2 PF14523.1 AAS54845.1 - 0.078 13.0 0.1 0.097 12.7 0.1 1.2 1 0 0 1 1 1 0 Syntaxin-like protein Prenyltransf PF01255.14 AAS54845.1 - 0.082 12.0 0.0 0.095 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Peripla_BP_2 PF01497.13 AAS54845.1 - 0.084 11.9 0.0 0.084 11.9 0.0 1.0 1 0 0 1 1 1 0 Periplasmic binding protein DUF3251 PF11622.3 AAS54845.1 - 0.11 11.8 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Oxysterol_BP PF01237.13 AAS54846.1 - 4e-105 351.1 0.1 6.4e-105 350.5 0.1 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 AAS54846.1 - 1.9e-32 111.1 0.3 6.3e-32 109.5 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 AAS54846.1 - 0.0009 19.4 0.2 0.0045 17.1 0.1 2.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 AAS54846.1 - 0.063 13.5 7.2 0.078 13.2 2.4 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain Asparaginase PF00710.15 AAS54847.1 - 2.7e-70 236.7 0.0 3.2e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Asparaginase CN_hydrolase PF00795.17 AAS54848.1 - 1.2e-24 86.6 0.0 1.9e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 AAS54848.1 - 2.6e-24 85.4 0.0 7.4e-24 83.9 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 AAS54848.1 - 0.0012 18.3 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase Abhydrolase_6 PF12697.2 AAS54849.1 - 5.7e-22 78.7 0.0 8.6e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AAS54849.1 - 3.3e-09 36.6 0.0 6.9e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AAS54849.1 - 1.1e-08 35.0 0.0 6.8e-07 29.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 AAS54849.1 - 9.4e-05 22.1 0.0 0.00024 20.8 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 AAS54849.1 - 0.00053 19.6 0.0 0.00099 18.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 AAS54849.1 - 0.0023 17.7 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Cutinase PGAP1 PF07819.8 AAS54849.1 - 0.0042 16.7 0.0 0.0075 15.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 AAS54849.1 - 0.01 16.0 0.1 0.096 12.8 0.0 2.2 1 1 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.3 AAS54849.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF676 PF05057.9 AAS54849.1 - 0.045 13.0 0.1 0.088 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) VirJ PF06057.6 AAS54849.1 - 0.053 13.3 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) DUF2305 PF10230.4 AAS54849.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Peptidase_M1 PF01433.15 AAS54850.1 - 3.8e-123 411.4 2.4 3.9e-122 408.1 0.7 2.4 2 1 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 AAS54850.1 - 3.3e-26 92.3 0.0 5.7e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 AAS54850.1 - 2.6e-15 56.5 0.0 8.5e-15 54.9 0.0 1.9 1 1 0 1 1 1 1 Peptidase MA superfamily PBP PF01161.15 AAS54851.1 - 1.3e-13 51.0 0.0 2.5e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ATP-synt_E PF05680.7 AAS54852.1 - 7.3e-22 77.1 0.4 7.9e-22 77.0 0.3 1.0 1 0 0 1 1 1 1 ATP synthase E chain SpoIIE PF07228.7 AAS54853.1 - 2.1e-28 99.3 0.0 3.1e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 AAS54853.1 - 1.1e-08 34.7 0.1 0.00068 19.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 AAS54853.1 - 1.7e-06 27.6 0.1 3.6e-06 26.5 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C MIF4G PF02854.14 AAS54854.2 - 3e-35 121.5 34.9 2e-15 56.7 7.6 3.9 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 AAS54854.2 - 1.9e-16 60.3 26.0 1.2e-15 57.6 18.0 2.3 1 1 0 1 1 1 1 Up-frameshift suppressor 2 CDC45 PF02724.9 AAS54854.2 - 8.1 4.3 23.3 18 3.2 16.2 1.5 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 AAS54854.2 - 9.2 5.4 13.2 16 4.6 9.2 1.4 1 0 0 1 1 1 0 NOA36 protein FYVE PF01363.16 AAS54855.1 - 4e-17 61.8 25.7 2.2e-15 56.3 1.9 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 AAS54855.1 - 5.2e-05 22.7 1.8 5.2e-05 22.7 1.3 2.1 2 0 0 2 2 2 1 Rabenosyn Rab binding domain FYVE_2 PF02318.11 AAS54855.1 - 0.0058 16.5 1.7 0.0058 16.5 1.2 3.2 2 0 0 2 2 2 1 FYVE-type zinc finger zf-C2H2_4 PF13894.1 AAS54855.1 - 0.024 14.9 0.1 0.024 14.9 0.0 6.1 4 2 1 5 5 5 0 C2H2-type zinc finger Rad50_zn_hook PF04423.9 AAS54855.1 - 0.025 14.0 8.8 0.48 9.9 0.0 4.0 4 0 0 4 4 4 0 Rad50 zinc hook motif HypA PF01155.14 AAS54855.1 - 0.3 10.7 10.5 2.3 7.9 1.7 3.5 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family ABA_GPCR PF12430.3 AAS54856.1 - 1.6e-54 184.0 6.3 1.6e-54 184.0 4.4 2.8 3 1 0 3 3 3 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 AAS54856.1 - 9.3e-19 67.2 0.0 3.6e-18 65.3 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) WD40 PF00400.27 AAS54857.2 - 4.3e-17 61.2 15.5 0.17 11.8 0.1 9.8 10 0 0 10 10 10 8 WD domain, G-beta repeat AhpC-TSA PF00578.16 AAS54858.2 - 1.4e-30 105.4 0.0 2e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 AAS54858.2 - 7.6e-14 51.0 0.1 1.2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 AAS54858.2 - 1.7e-08 34.1 0.0 2.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin Fungal_trans PF04082.13 AAS54859.1 - 1.3e-23 83.1 3.5 2.3e-23 82.3 2.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AAS54859.1 - 3.1e-09 36.5 9.9 4.9e-09 35.9 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UCH PF00443.24 AAS54860.2 - 6.3e-72 241.9 0.0 1.5e-71 240.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AAS54860.2 - 1.6e-28 100.0 2.4 1e-21 77.6 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pribosyltran_N PF13793.1 AAS54861.1 - 6.2e-45 151.6 0.2 2.3e-42 143.3 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 AAS54861.1 - 6.5e-36 123.7 2.1 1.5e-29 103.0 1.3 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 AAS54861.1 - 3.5e-11 42.9 1.6 6.1e-11 42.1 0.1 2.1 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AAS54861.1 - 0.0013 18.0 0.1 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UQ_con PF00179.21 AAS54862.1 - 8.4e-29 99.7 0.1 1.4e-28 99.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AAS54862.1 - 0.0033 17.1 0.0 0.0085 15.8 0.0 1.7 1 1 1 2 2 2 1 Prokaryotic E2 family B ADH_zinc_N_2 PF13602.1 AAS54863.2 - 1.5e-12 48.4 0.0 3.1e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AAS54863.2 - 1.6e-07 31.0 0.0 2.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain zf-CSL PF05207.8 AAS54864.1 - 1.7e-24 85.0 3.2 2.1e-24 84.7 2.2 1.1 1 0 0 1 1 1 1 CSL zinc finger Ribosomal_S8e PF01201.17 AAS54865.1 - 1.2e-51 174.3 2.2 1.3e-51 174.1 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e AAR2 PF05282.6 AAS54866.2 - 3.9e-67 226.7 0.0 4.6e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein EMP24_GP25L PF01105.19 AAS54867.1 - 1.2e-05 25.1 0.0 3e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1465 PF07323.7 AAS54868.1 - 0.0094 15.5 1.0 0.013 15.1 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1465) Exonuc_VII_L PF02601.10 AAS54868.1 - 0.012 14.8 0.3 0.013 14.6 0.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 AAS54868.1 - 0.036 13.6 2.2 0.043 13.4 1.5 1.1 1 0 0 1 1 1 0 IncA protein Spc24 PF08286.6 AAS54868.1 - 0.062 12.9 0.6 0.077 12.6 0.4 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 KfrA_N PF11740.3 AAS54868.1 - 1.3 9.5 13.8 2 8.8 9.5 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term SNF2_N PF00176.18 AAS54869.2 - 4e-71 239.2 1.5 4e-71 239.2 1.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain DBINO PF13892.1 AAS54869.2 - 5.4e-53 178.7 23.0 5.4e-53 178.7 15.9 5.2 7 0 0 7 7 7 1 DNA-binding domain Helicase_C PF00271.26 AAS54869.2 - 5e-14 51.9 0.0 2e-13 49.9 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Med5 PF08689.5 AAS54870.1 - 8.7e-296 983.6 18.8 9.8e-296 983.5 13.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 Pex14_N PF04695.8 AAS54871.1 - 4.6e-34 117.3 0.4 4e-33 114.3 0.3 2.3 1 1 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 AAS54871.1 - 0.0011 18.6 10.6 0.0023 17.5 7.3 1.5 1 0 0 1 1 1 1 IncA protein AAA_13 PF13166.1 AAS54871.1 - 0.0021 16.6 1.9 0.0026 16.3 1.3 1.1 1 0 0 1 1 1 1 AAA domain XRCC4 PF06632.7 AAS54871.1 - 0.0044 15.9 1.0 0.0053 15.6 0.7 1.2 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 CCDC-167 PF15188.1 AAS54871.1 - 0.014 15.3 1.4 0.014 15.3 1.0 2.5 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 YPEB PF14620.1 AAS54871.1 - 0.015 14.3 1.2 0.02 13.9 0.8 1.2 1 0 0 1 1 1 0 YpeB sporulation SF-assemblin PF06705.6 AAS54871.1 - 0.026 13.6 10.7 0.042 12.9 7.4 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin DUF1043 PF06295.7 AAS54871.1 - 0.038 13.6 1.0 0.038 13.6 0.7 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) MCPsignal PF00015.16 AAS54871.1 - 0.046 13.2 0.3 0.072 12.6 0.2 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF342 PF03961.8 AAS54871.1 - 0.049 12.0 8.6 0.056 11.8 5.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) NCA2 PF08637.5 AAS54871.1 - 0.054 12.3 3.6 0.74 8.6 0.4 2.1 1 1 1 2 2 2 0 ATP synthase regulation protein NCA2 Reo_sigmaC PF04582.7 AAS54871.1 - 0.056 12.6 0.1 0.083 12.0 0.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ECH_C PF13766.1 AAS54871.1 - 0.063 13.4 1.2 0.16 12.1 0.7 1.9 1 1 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region DUF812 PF05667.6 AAS54871.1 - 0.074 11.5 9.5 0.11 11.0 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Myosin_tail_1 PF01576.14 AAS54871.1 - 0.078 10.6 16.5 0.13 9.9 11.5 1.3 1 0 0 1 1 1 0 Myosin tail Baculo_PEP_C PF04513.7 AAS54871.1 - 0.079 12.7 3.4 0.11 12.3 0.7 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 AAS54871.1 - 0.1 9.9 9.8 0.15 9.3 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_II PF06009.7 AAS54871.1 - 0.11 12.3 7.7 0.23 11.2 5.3 1.6 1 0 0 1 1 1 0 Laminin Domain II IFT57 PF10498.4 AAS54871.1 - 0.12 11.0 10.5 0.17 10.5 7.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TBPIP PF07106.8 AAS54871.1 - 0.28 10.7 10.3 0.97 8.9 7.1 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 AAS54871.1 - 0.28 9.7 12.3 0.42 9.2 8.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.6 AAS54871.1 - 0.33 10.8 2.8 4.3 7.2 1.0 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ISG65-75 PF11727.3 AAS54871.1 - 0.44 9.5 4.4 0.73 8.8 3.0 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Seryl_tRNA_N PF02403.17 AAS54871.1 - 0.68 9.9 11.9 2 8.4 8.1 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 AAS54871.1 - 0.69 8.9 14.1 1 8.3 9.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 AAS54871.1 - 0.8 9.5 15.7 0.17 11.6 3.7 3.2 1 1 2 3 3 3 0 Prefoldin subunit LXG PF04740.7 AAS54871.1 - 1.2 8.9 12.6 1.3 8.7 3.2 2.4 1 1 1 2 2 2 0 LXG domain of WXG superfamily STAT_alpha PF01017.15 AAS54871.1 - 1.2 8.8 10.8 2.6 7.7 7.5 1.6 1 1 0 1 1 1 0 STAT protein, all-alpha domain DUF1664 PF07889.7 AAS54871.1 - 1.8 8.3 7.3 20 4.9 3.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 AAS54871.1 - 3.6 7.4 14.4 0.4 10.5 4.0 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Allexi_40kDa PF05549.6 AAS54871.1 - 6.1 6.0 6.7 3.7 6.7 2.0 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein V_ATPase_I PF01496.14 AAS54871.1 - 8.3 4.1 9.6 12 3.6 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ACPS PF01648.15 AAS54872.2 - 3.2e-07 30.1 0.0 5.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Mito_carr PF00153.22 AAS54873.1 - 2.6e-52 174.5 0.6 1.8e-20 72.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Prenyltrans PF00432.16 AAS54874.1 - 1e-20 72.9 14.3 2.5e-05 23.7 0.1 5.1 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AAS54874.1 - 1.4e-15 57.6 0.0 7.3e-06 26.3 0.0 3.5 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 AAS54874.1 - 0.00097 19.1 0.0 0.0088 16.0 0.0 2.5 2 2 1 3 3 3 1 Prenyltransferase-like Glyco_hydro_38 PF01074.17 AAS54875.2 - 1.8e-80 270.1 1.0 3.3e-80 269.2 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 AAS54875.2 - 9.4e-60 202.6 2.1 1.3e-59 202.2 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 AAS54875.2 - 2.6e-23 82.0 0.0 6.4e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Inhibitor_I9 PF05922.11 AAS54876.1 - 1.2e-05 25.7 0.1 4.8e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 DrrA_P4M PF14860.1 AAS54876.1 - 0.017 14.8 0.3 0.018 14.7 0.2 1.1 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain DUF4265 PF14085.1 AAS54876.1 - 0.11 12.1 0.1 0.15 11.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4265) Frataxin_Cyay PF01491.11 AAS54877.2 - 1.1e-33 115.3 0.0 1.3e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain UCH PF00443.24 AAS54879.1 - 1.5e-45 155.4 0.0 1.9e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AAS54879.1 - 6.6e-13 48.7 0.0 5.8e-06 25.9 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase COG2 PF06148.6 AAS54879.1 - 0.12 12.2 0.6 0.3 10.9 0.4 1.7 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 RRM_1 PF00076.17 AAS54880.1 - 1.4e-51 172.0 1.4 3.1e-18 65.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AAS54880.1 - 1.2e-29 102.0 0.2 1.8e-11 43.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AAS54880.1 - 3.8e-25 87.5 1.5 1.7e-08 34.1 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AAS54880.1 - 0.038 13.8 0.3 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.1 AAS54880.1 - 0.084 12.6 0.1 1.5 8.6 0.0 2.6 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DFP PF04127.10 AAS54881.2 - 4e-18 65.7 0.1 3.2e-09 36.6 0.0 2.6 3 0 0 3 3 3 2 DNA / pantothenate metabolism flavoprotein Peptidase_A2B PF12384.3 AAS54881.2 - 0.14 11.5 0.0 0.59 9.4 0.0 1.9 2 0 0 2 2 2 0 Ty3 transposon peptidase Bac_surface_Ag PF01103.18 AAS54882.1 - 1.5e-38 133.0 0.2 7.1e-38 130.8 0.1 1.9 1 1 0 1 1 1 1 Surface antigen DnaJ PF00226.26 AAS54883.1 - 7.1e-06 25.6 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain AAA PF00004.24 AAS54884.1 - 8e-55 184.6 0.0 3.3e-44 150.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AAS54884.1 - 1.2e-07 32.5 0.0 0.0013 19.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AAS54884.1 - 4.8e-05 23.4 0.2 0.019 14.9 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 AAS54884.1 - 0.00012 22.1 0.0 0.0047 17.0 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.1 AAS54884.1 - 0.00046 19.6 0.2 0.02 14.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AAS54884.1 - 0.0006 19.7 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AAS54884.1 - 0.00069 18.7 0.0 0.0023 17.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 AAS54884.1 - 0.001 18.9 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 AAS54884.1 - 0.0017 18.2 0.0 0.0047 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 AAS54884.1 - 0.0018 18.4 0.0 0.031 14.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Parvo_NS1 PF01057.12 AAS54884.1 - 0.0021 16.9 0.0 0.0046 15.8 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.12 AAS54884.1 - 0.003 16.9 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 AAS54884.1 - 0.0064 16.8 0.0 0.15 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 AAS54884.1 - 0.0086 15.7 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 AAS54884.1 - 0.0099 14.6 0.1 0.04 12.6 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 AAS54884.1 - 0.011 15.5 0.0 0.053 13.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 AAS54884.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.16 AAS54884.1 - 0.016 14.3 0.1 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 AAS54884.1 - 0.017 14.8 0.0 0.049 13.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 AAS54884.1 - 0.018 14.9 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 AAS54884.1 - 0.038 13.2 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 AAS54884.1 - 0.056 13.0 0.6 0.15 11.5 0.1 2.1 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.6 AAS54884.1 - 0.12 11.9 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Hist_deacetyl PF00850.14 AAS54885.1 - 1e-80 271.3 0.0 1.6e-80 270.7 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain DMRL_synthase PF00885.14 AAS54886.2 - 1.7e-43 147.7 0.1 2.1e-43 147.4 0.1 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase RRM_5 PF13893.1 AAS54887.2 - 3.9e-09 36.2 0.1 7.9e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AAS54887.2 - 0.00037 20.0 0.0 0.00091 18.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FB_lectin PF07367.6 AAS54887.2 - 0.059 12.9 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Fungal fruit body lectin RRM_6 PF14259.1 AAS54887.2 - 0.12 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TPR_2 PF07719.12 AAS54888.1 - 4.5e-28 94.8 22.4 0.00021 20.9 0.2 11.5 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_11 PF13414.1 AAS54888.1 - 2e-24 85.0 20.9 3.1e-06 26.7 0.0 9.6 6 3 3 10 10 9 8 TPR repeat TPR_1 PF00515.23 AAS54888.1 - 8.7e-23 78.9 28.2 0.0013 18.2 0.0 11.7 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_12 PF13424.1 AAS54888.1 - 1.9e-20 72.5 18.1 7.9e-06 25.7 0.0 9.0 5 3 6 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.1 AAS54888.1 - 4.6e-17 62.1 10.7 0.00045 20.8 0.1 8.2 7 2 3 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 AAS54888.1 - 7.2e-16 58.2 26.5 0.002 18.4 0.1 8.9 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 AAS54888.1 - 1.9e-12 46.6 22.0 0.0073 16.8 0.1 11.8 12 3 3 15 15 12 3 Tetratricopeptide repeat TPR_8 PF13181.1 AAS54888.1 - 3.4e-12 45.2 27.4 0.34 10.7 0.0 12.0 13 1 0 13 13 13 6 Tetratricopeptide repeat Apc3 PF12895.2 AAS54888.1 - 3.6e-12 46.2 17.5 0.0038 17.3 0.1 7.0 5 1 2 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 AAS54888.1 - 1.3e-07 31.6 23.1 0.27 11.7 0.5 10.5 12 0 0 12 12 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 AAS54888.1 - 1.5e-05 24.3 26.0 1 9.3 0.1 10.4 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_17 PF13431.1 AAS54888.1 - 0.00031 20.6 12.6 16 5.9 0.0 9.4 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_3 PF07720.7 AAS54888.1 - 0.059 13.1 0.1 0.059 13.1 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 AAS54888.1 - 0.076 12.9 21.0 5 7.1 0.4 8.5 10 0 0 10 10 9 0 Tetratricopeptide repeat Sld5 PF05916.6 AAS54889.1 - 3.8e-10 40.0 0.0 4.8e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein PEX11 PF05648.9 AAS54890.1 - 5.1e-62 209.0 1.5 5.9e-62 208.8 1.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Spt20 PF12090.3 AAS54891.1 - 6.5e-55 185.3 0.4 2.9e-54 183.1 0.0 2.2 2 0 0 2 2 2 1 Spt20 family DCP1 PF06058.8 AAS54892.1 - 7e-20 71.3 1.5 1.4e-10 41.2 0.0 3.0 2 1 1 3 3 3 3 Dcp1-like decapping family GFO_IDH_MocA PF01408.17 AAS54893.1 - 6.6e-22 78.2 1.4 6.6e-22 78.2 1.0 2.0 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 AAS54893.1 - 2.7e-10 40.0 0.0 5.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Shikimate_DH PF01488.15 AAS54893.1 - 0.0079 16.2 0.3 0.088 12.9 0.2 2.4 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 AAS54893.1 - 0.018 15.4 1.5 0.058 13.8 0.2 2.6 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent UPF0449 PF15136.1 AAS54893.1 - 0.024 14.8 0.0 6.2 7.0 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 NAD_binding_3 PF03447.11 AAS54893.1 - 0.032 14.6 1.6 0.077 13.4 1.1 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain TrmB PF01978.14 AAS54893.1 - 0.075 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Peptidase_M3 PF01432.15 AAS54895.2 - 8.6e-134 447.0 0.1 1.3e-133 446.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M3 PF01432.15 AAS54896.1 - 7.9e-134 447.1 0.0 1e-133 446.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 AAS54896.1 - 0.23 10.8 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Asp PF00026.18 AAS54897.2 - 4.1e-81 272.6 0.0 4.8e-81 272.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 AAS54897.2 - 6.5e-10 38.7 0.0 1.5e-08 34.3 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 AAS54897.2 - 3.5e-07 30.3 0.0 5.9e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AAS54897.2 - 0.013 16.0 0.1 0.07 13.6 0.0 2.2 2 1 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.1 AAS54897.2 - 0.013 15.3 0.1 0.05 13.4 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CYSTM PF12734.2 ADJ41736.1 - 0.00034 20.6 11.3 0.00034 20.6 7.9 1.9 2 0 0 2 2 2 1 Cysteine-rich TM module stress tolerance Cyt-b5 PF00173.23 ADJ41737.1 - 4.6e-12 45.5 0.0 6.6e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HMG_box PF00505.14 ADJ41738.1 - 1e-34 118.6 13.1 2.9e-18 65.8 3.7 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 ADJ41738.1 - 1.6e-21 76.4 9.9 3.1e-12 46.6 2.9 2.4 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.7 ADJ41738.1 - 8.6e-05 22.1 0.0 0.21 11.2 0.0 2.4 2 0 0 2 2 2 2 CHDNT (NUC034) domain Tol_Tol_Ttg2 PF05494.7 ADJ41738.1 - 0.001 18.6 0.3 0.21 11.1 0.0 2.2 2 0 0 2 2 2 2 Toluene tolerance, Ttg2 4HB_MCP_1 PF12729.2 ADJ41738.1 - 2.8 7.2 5.4 0.6 9.4 0.9 1.8 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction zinc_ribbon_6 PF14599.1 ADJ41739.1 - 2.1e-25 88.2 0.1 2.1e-25 88.2 0.1 2.9 3 0 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.7 ADJ41739.1 - 4.9e-12 45.8 15.5 4.9e-12 45.8 10.8 4.4 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 ADJ41739.1 - 6.3e-08 32.3 9.7 6.3e-08 32.3 6.8 5.1 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 ADJ41739.1 - 0.00014 21.7 9.1 0.00014 21.7 6.3 5.5 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 ADJ41739.1 - 0.0037 16.9 11.0 0.0037 16.9 7.6 6.1 3 3 2 5 5 5 1 zinc-RING finger domain Mito_fiss_reg PF05308.6 ADJ41739.1 - 0.037 13.4 1.5 0.074 12.4 1.0 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 ADJ41739.1 - 1 8.5 10.0 1.9 7.7 6.9 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Acetyltransf_1 PF00583.19 ADJ41740.1 - 1.2e-16 60.4 0.0 2.1e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 ADJ41740.1 - 3e-09 36.9 0.1 5e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 ADJ41740.1 - 1.1e-05 25.0 0.1 3.1e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 ADJ41740.1 - 2.5e-05 24.3 0.0 3.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 ADJ41740.1 - 0.0023 17.7 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 ADJ41740.1 - 0.0076 16.4 0.0 0.0091 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 ADJ41740.1 - 0.0092 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 ADJ41740.1 - 0.022 14.7 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain B12D PF06522.6 ADJ41741.1 - 0.00057 19.5 0.2 0.00084 18.9 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit SKG6 PF08693.5 ADJ41743.1 - 3.2e-06 26.3 0.9 4.7e-06 25.8 0.6 1.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain ETRAMP PF09716.5 ADJ41743.1 - 0.055 13.4 0.1 0.08 12.9 0.1 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Sex_peptide PF08138.6 ADJ41743.1 - 0.086 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Sex peptide (SP) family ADIP PF11559.3 ADJ41744.1 - 0.012 15.4 3.6 0.047 13.5 0.0 2.7 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding AKNA PF12443.3 ADJ41744.1 - 0.03 14.3 0.0 0.083 12.9 0.0 1.7 2 0 0 2 2 2 0 AT-hook-containing transcription factor SlyX PF04102.7 ADJ41744.1 - 9 6.7 10.2 5.2 7.5 0.1 3.3 3 1 0 3 3 3 0 SlyX HSP20 PF00011.16 ADJ41746.1 - 3.6e-20 71.7 0.3 5.2e-20 71.2 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BON PF04972.12 ADJ41746.1 - 0.0098 15.6 0.0 2.3 8.0 0.0 2.5 2 0 0 2 2 2 2 BON domain Transpos_assoc PF13963.1 ADJ41747.1 - 0.055 13.4 0.1 0.062 13.2 0.0 1.1 1 0 0 1 1 1 0 Transposase-associated domain COX7C PF02935.11 ADJ41748.1 - 0.092 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc DUF1067 PF06362.6 ADJ41751.1 - 0.39 11.3 4.6 2.7 8.6 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1067) DUF883 PF05957.8 ADJ41753.1 - 0.14 12.6 0.1 0.16 12.3 0.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) MT0933_antitox PF14013.1 ADJ41753.1 - 3.5 7.7 6.0 4.7 7.3 4.1 1.3 1 1 0 1 1 1 0 MT0933-like antitoxin protein DPM2 PF07297.7 ADJ41754.1 - 6.5e-12 45.5 0.7 7.2e-12 45.4 0.5 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Oxidored_q4 PF00507.14 ADJ41754.1 - 0.2 11.4 1.5 0.22 11.3 1.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF4229 PF14012.1 ADJ41754.1 - 0.72 9.7 6.8 1.8 8.5 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4229) FtsX PF02687.16 ADJ41754.1 - 0.85 9.3 5.7 1.1 9.0 4.0 1.1 1 0 0 1 1 1 0 FtsX-like permease family DUF1049 PF06305.6 ADJ41754.1 - 8.5 5.9 9.1 0.47 9.9 2.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Cellsynth_D PF03500.8 ADJ41755.1 - 0.049 13.3 0.0 0.058 13.0 0.0 1.1 1 0 0 1 1 1 0 Cellulose synthase subunit D AAA_32 PF13654.1 ADJ41755.1 - 0.067 11.8 0.0 0.067 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain P63C PF10546.4 ADJ41755.1 - 0.12 12.3 0.2 2.8 7.9 0.0 2.0 1 1 1 2 2 2 0 P63C domain Pyrid_oxidase_2 PF13883.1 ADJ41757.1 - 4.4e-22 78.6 0.0 6.3e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 ADJ41757.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.7 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.1 ADJ41758.1 - 3e-16 59.6 0.0 4.3e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RNase_H2_suC PF08615.6 ADJ41759.1 - 0.069 12.9 0.0 1 9.1 0.0 2.1 1 1 1 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Rtf2 PF04641.7 ADJ41760.1 - 1.3e-33 116.3 0.0 3.2e-33 115.0 0.0 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger Glyco_transf_15 PF01793.11 ADJ41761.1 - 3.1e-142 473.3 14.3 3.9e-142 473.0 9.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DNA_pol_alpha_N PF12254.3 ADJ41761.1 - 0.024 14.4 0.0 5.4 6.9 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal zf-C2H2 PF00096.21 ADJ41763.1 - 1.3e-09 37.7 6.8 0.00023 21.3 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 ADJ41763.1 - 1.1e-08 34.7 4.7 0.0005 20.1 0.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 ADJ41763.1 - 5.7e-07 29.5 14.2 0.00065 19.8 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 ADJ41763.1 - 0.00011 22.2 4.8 0.002 18.2 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 ADJ41763.1 - 0.0039 16.8 0.5 0.44 10.2 0.0 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type DUF2256 PF10013.4 ADJ41763.1 - 0.1 12.3 0.4 0.1 12.3 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-Di19 PF05605.7 ADJ41763.1 - 0.53 10.4 7.4 3.5 7.8 0.9 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CYSTM PF12734.2 ADJ41764.1 - 0.00089 19.2 35.5 0.018 15.1 24.6 2.6 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance DUF2130 PF09903.4 ADJ41765.1 - 0.0022 16.8 0.8 0.0024 16.6 0.6 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2130) Spectrin PF00435.16 ADJ41765.1 - 0.017 15.4 0.6 0.02 15.1 0.4 1.1 1 0 0 1 1 1 0 Spectrin repeat Sipho_Gp157 PF05565.6 ADJ41765.1 - 0.02 14.4 1.1 0.023 14.3 0.8 1.0 1 0 0 1 1 1 0 Siphovirus Gp157 BLOC1_2 PF10046.4 ADJ41765.1 - 0.056 13.5 1.2 0.065 13.3 0.9 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PilJ PF13675.1 ADJ41765.1 - 0.056 13.7 0.1 0.064 13.5 0.1 1.0 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Tropomyosin_1 PF12718.2 ADJ41765.1 - 0.076 12.8 3.6 0.11 12.2 2.4 1.4 1 1 0 1 1 1 0 Tropomyosin like Exonuc_VII_S PF02609.11 ADJ41765.1 - 0.096 12.4 0.8 0.16 11.7 0.6 1.4 1 0 0 1 1 1 0 Exonuclease VII small subunit DUF2951 PF11166.3 ADJ41765.1 - 0.098 12.5 0.7 0.12 12.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) APG6 PF04111.7 ADJ41765.1 - 0.11 11.5 1.9 0.13 11.3 1.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 TGT_C1 PF14809.1 ADJ41768.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 C1 domain of tRNA-guanine transglycosylase dimerisation eIF3_N PF09440.5 ADJ41768.1 - 0.14 12.2 0.2 1.3 9.1 0.1 2.0 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain RR_TM4-6 PF06459.7 ADJ41769.1 - 0.46 10.3 11.2 0.49 10.2 7.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSCB_C PF07743.8 ADJ41769.1 - 0.65 10.4 3.6 2.8 8.4 2.5 1.9 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain ASFV_J13L PF05568.6 ADJ41769.1 - 4.9 6.6 9.6 6.1 6.3 6.7 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein Cuticle_3 PF11018.3 ADJ41769.1 - 6.4 6.8 19.1 7.6 6.6 13.2 1.2 1 0 0 1 1 1 0 Pupal cuticle protein C1 CPSF_A PF03178.10 ADJ41773.1 - 3.5e-05 23.0 0.0 0.00028 20.0 0.0 2.3 2 1 0 2 2 2 1 CPSF A subunit region PMP1_2 PF08114.6 ADJ41774.1 - 0.00039 19.8 1.8 0.00041 19.7 1.2 1.2 1 0 0 1 1 1 1 ATPase proteolipid family VPEP PF07589.6 ADJ41774.1 - 0.18 11.7 3.0 0.41 10.6 2.1 1.6 1 1 0 1 1 1 0 PEP-CTERM motif YbgT_YccB PF08173.6 ADJ41774.1 - 0.94 9.3 3.3 0.75 9.6 1.4 1.7 1 1 0 1 1 1 0 Membrane bound YbgT-like protein Phage_int_SAM_1 PF02899.12 ADJ41775.1 - 0.047 13.8 0.3 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF2570 PF10828.3 ADJ41777.1 - 0.18 11.3 4.4 0.54 9.8 3.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) APG6 PF04111.7 ADJ41777.1 - 0.56 9.2 23.4 0.018 14.1 10.7 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF3166 PF11365.3 ADJ41777.1 - 0.69 10.4 8.9 0.32 11.4 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) V_ATPase_I PF01496.14 ADJ41777.1 - 6.7 4.4 5.9 13 3.5 4.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 ADJ41777.1 - 7.3 6.3 28.8 6.6 6.4 13.1 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ERM PF00769.14 ADJ41779.1 - 0.0096 15.4 7.0 0.014 14.9 4.9 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Corona_S2 PF01601.11 ADJ41779.1 - 0.069 11.2 1.9 0.1 10.6 1.3 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein ApoO PF09769.4 ADJ41779.1 - 0.07 12.8 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Apolipoprotein O WD40_alt PF14077.1 ADJ41779.1 - 0.11 12.2 0.5 3.5 7.3 0.0 2.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF4250 PF14056.1 ADJ41779.1 - 0.12 12.1 0.7 2.6 7.8 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Troponin PF00992.15 ADJ41779.1 - 0.38 10.8 10.5 0.24 11.4 5.5 1.9 2 0 0 2 2 2 0 Troponin ATG16 PF08614.6 ADJ41779.1 - 0.52 10.1 15.9 1.1 9.0 7.9 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF2762 PF10960.3 ADJ41779.1 - 0.56 9.9 6.5 0.1 12.2 1.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2762) BRE1 PF08647.6 ADJ41779.1 - 0.64 10.0 13.3 0.27 11.2 2.7 3.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Syntaxin_2 PF14523.1 ADJ41779.1 - 1.4 8.9 9.7 9.6 6.3 0.0 3.1 2 1 1 3 3 3 0 Syntaxin-like protein IncA PF04156.9 ADJ41779.1 - 3 7.3 15.5 1e+02 2.4 11.0 2.3 1 1 0 1 1 1 0 IncA protein LMBR1 PF04791.11 ADJ41780.1 - 4.8e-13 48.5 14.2 3.9e-10 38.9 1.4 2.2 2 0 0 2 2 2 2 LMBR1-like membrane protein Antigen_Bd37 PF11641.3 ADJ41780.1 - 0.097 11.9 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein YibE_F PF07907.6 ADJ41781.1 - 0.00075 18.7 12.9 0.0011 18.2 9.0 1.2 1 0 0 1 1 1 1 YibE/F-like protein DUF4526 PF15029.1 ADJ41781.1 - 0.046 13.2 1.7 0.079 12.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) DUF3329 PF11808.3 ADJ41781.1 - 0.07 13.2 0.0 0.07 13.2 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3329) RNase_H2_suC PF08615.6 ADJ41782.1 - 0.069 12.9 0.0 1 9.1 0.0 2.1 1 1 1 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF4316 PF14195.1 ADJ41786.1 - 2.7 8.1 6.6 3.8 7.6 4.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4316) Sec3_C PF09763.4 ADJ41787.1 - 0.16 10.0 0.0 0.22 9.5 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Methyltransf_30 PF05430.6 ADJ41789.1 - 0.034 13.8 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase RRM_1 PF00076.17 ADJ41790.1 - 9.3e-07 28.3 0.4 2.6e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 ADJ41790.1 - 0.0001 22.1 0.2 0.00033 20.4 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Neugrin PF06413.6 ADJ41790.1 - 0.0021 17.8 0.6 0.0032 17.3 0.4 1.2 1 0 0 1 1 1 1 Neugrin Nup35_RRM_2 PF14605.1 ADJ41790.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 ADJ41790.1 - 0.021 14.6 2.7 0.64 9.8 0.0 2.8 2 1 1 3 3 3 0 RNA binding motif RRM_6 PF14259.1 ADJ41790.1 - 0.023 14.6 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SCIMP PF15050.1 ADJ41791.1 - 0.48 10.3 2.0 0.48 10.3 1.4 1.1 1 0 0 1 1 1 0 SCIMP protein RNase_H2_suC PF08615.6 ADJ41794.1 - 0.068 13.0 0.0 1 9.1 0.0 2.1 1 1 1 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Sec10 PF07393.6 ADJ41795.1 - 3.7e-32 111.3 0.0 4e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 RNase_H2_suC PF08615.6 ADJ41796.1 - 0.068 13.0 0.0 1 9.1 0.0 2.1 1 1 1 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) HMG_box PF00505.14 ADJ41797.1 - 0.12 12.6 1.7 2.2 8.6 1.2 2.3 1 1 0 1 1 1 0 HMG (high mobility group) box Homeobox PF00046.24 ADJ41798.1 - 5.3e-16 57.9 2.3 7e-16 57.5 1.6 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 ADJ41798.1 - 2e-05 24.2 0.3 3.6e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Homeobox KN domain SUI1 PF01253.17 ADJ41799.1 - 7.9e-29 99.3 0.4 9.5e-29 99.0 0.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2575 PF10837.3 ADJ41799.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) Cas_Csa5 PF09702.5 ADJ41799.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) Pyrid_oxidase_2 PF13883.1 ADJ41800.1 - 3e-16 59.6 0.0 4.3e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.1 ADJ41801.1 - 4.4e-22 78.6 0.0 6.3e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 ADJ41801.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.7 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase OPT PF03169.10 ADJ41803.1 - 8.2e-153 510.1 41.0 9.4e-153 509.9 28.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF983 PF06170.7 ADJ41803.1 - 0.045 13.8 7.3 0.23 11.6 5.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF983) DUF2427 PF10348.4 ADJ41804.1 - 0.019 14.5 9.9 0.053 13.0 6.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2427)